PMID- 4284838 TI - Use of blood collected on filter paper disks in neutralization tests for poliovirus antibody. PMID- 4284839 TI - [The parotid gland and its surgical problems]. PMID- 4284840 TI - Mechanisms of pressor amine dependence. PMID- 4284841 TI - Multiple focal necrosis of the colon in the absence of occlusion of the mesenteric blood supply. PMID- 4284842 TI - Clincal and research problems of infectious hepatitis and homologous serum jaundice. PMID- 4284843 TI - Second pulmonary neoplasms among long-term survivors of lung cancer. PMID- 4284844 TI - Studies on tumours developing in hamsters following inoculation of SV-40 virus and BHK-21 cells. PMID- 4284845 TI - Histochemical demonstration of changes in enzymatic activity of KB cells produced by staphylococcal alpha and beta hemolysins. PMID- 4284846 TI - Multiple painful glomus tumors of the skin. Views on histogenesis: case report. PMID- 4284847 TI - The fine structure of apocrine hidrocystoma. PMID- 4284848 TI - Nipple adenoma and Paget's disease in a man. PMID- 4284849 TI - [Pharmacological (biological) pharmacopoeial methods. II. Determination of the effectiveness of corticotropin]. PMID- 4284850 TI - Study by the agar gel-precipitation method of specific antigens in organs of mice and rats with Mazurenko viral leukemia. PMID- 4284851 TI - Detection of specific antigen in tissues of mice with leukemia induced by Mazurenko virus using the in vitro cytotoxic reaction. PMID- 4284852 TI - Effect of atherogenic diet on activity of certain enzymes in blood and liver of rats. PMID- 4284853 TI - Enzyme activities of brain tissues in reflex epilepsy. PMID- 4284854 TI - [The ratio of various steroids in the urine of obese female patients following ACTH stimulation]. PMID- 4284855 TI - Splenic hematopoiesis, morphological and hematological relationships in grouped male mice (Mus musculus). PMID- 4284856 TI - The management of severe anemia due to iron deficiency and benign gynecologic disease. PMID- 4284857 TI - The effects of sex steroids on gonadotropins. PMID- 4284858 TI - Enzyme histochemistry of the menopausal ovary associated with normal and abnormal endometrium. PMID- 4284859 TI - Muco-epidermoid carcinoma of submandibular gland. PMID- 4284860 TI - Glomus tumor (chemodectoma) of the larynx. PMID- 4284861 TI - A study of provocative tests for angle closure glaucoma. PMID- 4284862 TI - Scleral buckling procedures. 8. Preoperative complications. PMID- 4284863 TI - Ocular injury due to formic acid. PMID- 4284864 TI - Juvenile nasopharyngeal angiofibroma in a female. Report of a case. PMID- 4284865 TI - Multicentric endobronchial myoblastoma. PMID- 4284866 TI - A convenient synthesis of (9,19-3H2)cholecalciferol 3,5-dinitrobenzoate and the mechanism of the precholecalciferol to calciferol reaction. PMID- 4284867 TI - The development of periodontal disease in experimental animals infected with polyoma virus. PMID- 4284868 TI - Zero-field electron magnetic resonance of irradiated glycine peptides. PMID- 4284869 TI - [Essay on the diagnostic interpretation of the sulfobromophthalein test. I. Introduction]. PMID- 4284870 TI - [Study of the factors which intervene in the physiopathologic modifications of sulfobromophthalein clearance from the blood]. PMID- 4284871 TI - [Improvement of the semilogarithmic diagram showing the slopes of sulfobromophthalein clearance; attempted correlative interpretation of so-called hepatic fixation and biliary elimination clearances]. PMID- 4284872 TI - [Substitutive hormone therapy in anterior hypopituitarism]. PMID- 4284873 TI - [Epileptic absence in children]. PMID- 4284874 TI - [83-75 C in otorhinolaryngology]. PMID- 4284875 TI - [Action of lumirelax (monocarbamate of guiacol glycerin ether) in anal fissures]. PMID- 4284876 TI - Dupuytren's contracture. The results of radical fasciectomy. PMID- 4284877 TI - [Syntheses in the polymyxin series. 10. Synthesis of colistin A (polymyxin E-1)]. PMID- 4284878 TI - [Synthesis of all-D-val-5-angiotensin II-asp-1-beta-amide]. PMID- 4284879 TI - Epidemic cutaneous herpes simplex in wrestlers (herpes gladiatorum). PMID- 4284881 TI - Help wanted. PMID- 4284880 TI - [Diagnostic and pathogenetic considerations on 2 cases of hyperinsulinism secondary to insular adenoma]. PMID- 4284882 TI - [Insulin resistance. 3. The role of pituitary and adrenal cortex hormones]. PMID- 4284883 TI - The plasma fibrinolytic system in patients with trophoblastic disease and undelivered hydatidiform mole. PMID- 4284884 TI - Adrenal blood flow and the adrenocortical response to corticotropin. PMID- 4284885 TI - Determination of CRF activity in rats treated with Monase, dexamethasone, and morphine. PMID- 4284886 TI - Effect of acute carotid arterial constriction on aldosterone secretion in dogs. PMID- 4284887 TI - The biosynthesis of serine in mouse brain extracts. PMID- 4284888 TI - Investigations of yeast L-lactate dyhydrogenase (cytochrome b2). II. Anaerobic spectrophotometric and electron spin resonance titrations. PMID- 4284889 TI - The electron transport system of Hydrogenomonas eutropha. II. Reduced nicotinamide adenine dinucleotide-menadione reductase. PMID- 4284890 TI - Studies on lipoyl dehydrogenase from Escherichia coli. PMID- 4284891 TI - The nature of the cofactor requirements of the hydrogenase system from Clostridium kluyveri. PMID- 4284892 TI - Drug-induced resistance to tissue calcification. PMID- 4284893 TI - [Comparative effects of noradrenaline and angiotensin on renal and femoral vascular resistances]. PMID- 4284894 TI - [Nycthemeral variations of plasma ACTH and cortisol in man]. PMID- 4284895 TI - [Variations of the minimum mortal dose and lethal dose 50 of "Columbia SK" (New Haven) poliomyelitis virus in the rat during the 12 months of the year and the 4 seasons]. PMID- 4284896 TI - Studies of human pulmonary connective tissue. II. Amino acid composition of residues following collagenase digestion of lung connective tissues. PMID- 4284897 TI - [Primary cancer of the liver. (Presentation of 16 cases)]. PMID- 4284898 TI - [Ultrastructure of human spongioblastomas]. PMID- 4284899 TI - [On necrotizing encephalitides and herpes simplex encephalitis in adults. With a report on an intra vitam proven case of fatal encephalitis caused by herpesvirus]. PMID- 4284900 TI - [Diffuse secondary leptomeningeal tumors]. PMID- 4284901 TI - Mechanism by which histamine and antihistamines affect permeability of "histo hematic" barriers. PMID- 4284902 TI - Metastatic bone neoplasms in the dog. PMID- 4284903 TI - [On peptide syntheses. 33.3. On angiotensin analogues. Synthesis of lys-6-val-5-, of tyr-3-val-5-, of tyr(Me)-4-val-5- and of tyr-8-val-5-angiotensin II-asp-l-beta amide]. PMID- 4284904 TI - [Leukopenia in perchlorate therapy]. PMID- 4284905 TI - [Bilateral Wilms' tumor in an infant]. PMID- 4284906 TI - Digestion of purine ribonucleotides by intestinal enzymes of the developing rat fetus. PMID- 4284907 TI - Doctors' new insight into common cold. PMID- 4284908 TI - [Possibilities of vascular surgery in the ear-nose-throat region]. PMID- 4284909 TI - Studies in enzyme histochemistry with particular reference to oral tissues. I. Priniciples of oxidative metabolism and dehydrogenase histochemistry. PMID- 4284910 TI - Successful treatment of bacterial endocarditis due to pseudomonas aeruginosa. PMID- 4284911 TI - [Wilms tumors in the ovary]. PMID- 4284912 TI - The carbohydrate moiety of house dust allergen. PMID- 4284913 TI - Morphology, antigenicity, and nucleic acid content of the Bacteroides sp. used in the culture of Entamoeba histolytica. AB - Albach, Richard A. (Lutheran General Hospital, Park Ridge, Ill.), James G. Shaffer, and Robert H. Watson. Morphology, antigenicity, and nucleic acid content of the Bacteroides sp. used in the culture of Entamoeba histolytica. J. Bacteriol. 90:1045-1053. 1965.-Certain changes in morphology, antigenicity, and nucleic acid content that occur in a culture of Bacteroides sp. in the presence of penicillin G in CLG medium are described. This "variant" is one of seven recovered in several laboratories, all of which are descendants of the original Bacteroides isolated by Shaffer and Frye. Penicillin-inhibited cells of this culture are currently being used in the routine propagation of Entamoeba histolytica in CLG medium. Evidence is presented for the loss of ability to react with antibody in these penicillin-inhibited bacteria in CLG medium, when studied by fluorescent-antibody techniques. The implications of the antigenic changes observed as they pertain to similar antigenic studies of the amoebas are discussed. A pronounced reduction in the ribonucleic acid (RNA) content of such penicillin-inhibited cells was also observed. The potential importance of the changes that occur in the RNA of these cells with respect to considerations of the growth requirements of the amoebas is also discussed. PMID- 4284914 TI - Characteristics of seven "variants" of the Bacteroides sp. used in the propagation of Entamoeba histolytica.. PMID- 4284915 TI - Genetic mapping off fructose-1,6-diphosphatase in Escherichia coli. PMID- 4284916 TI - Halophilic enzymes in cell-free extracts of Halobacterium salinarium. PMID- 4284917 TI - Fructose-1, 6-diphosphatase and acid hexose phosphatase of Escherichia coli. AB - Fraenkel, D. G. (Albert Einstein College of Medicine, New York, N.Y.), and B. L. Horecker. Fructose-1,6-diphosphatase and acid hexose phosphatase of Escherichia coli. J. Bacteriol. 90:837-842. 1965.-The conversion of fructose-1,6-diphosphate to fructose-6-phosphate (fructose-1,6-diphosphatase activity) is essential for growth of Escherichia coli on glycerol, acetate, or succinate, but is unnecessary for growth on hexoses or pentoses. It has sometimes been assumed that fructose 1,6-diphosphatase activity is due to a nonspecific acid hexose phosphatase. We have now obtained a number of one-step mutants which have lost the ability to grow on glycerol, succinate, or acetate, but which grow normally on hexoses; these mutants are deficient in a fructose-1,6-diphosphatase which can be assayed spectrophotometrically in the presence of Mg(++) and low concentrations of substrate. These mutants still possess the nonspecific acid hexose phosphatase, which does not require Mg(++) and is active only at much higher concentrations of fructose-1,6-diphosphate. Evidence is presented to support the hypothesis that the newly described activity is the physiological fructose-1,6-diphosphatase. The acid hexose phosphatase is a different enzyme whose function remains unknown. PMID- 4284918 TI - Effect of polymyxin B, tyrocidine, gramicidin D, and other antibiotics on the enzymatic hydrolysis of poly-beta-hydroxybutyrate. AB - Merrick, J. M. (State University of New York, Buffalo). Effect of polymyxin B, tyrocydine, gramicidin D, and other antibiotics on the enzymatic hydrolysis of poly-beta-hydroxybutyrate. J. Bacteriol. 90:965-969. 1965.-Previous studies have demonstrated that native poly-beta-hydroxybutyrate (PHB) granules isolated from Bacillus megaterium are surrounded by a discrete membranelike structure. Morphological alterations of PHB granules are mainly characterized by membrane fragmentation, and can be correlated with decreased susceptibility of the polymer to enzymatic hydrolysis by soluble factors. In the present investigation, the inhibitory effect of a variety of surface-active and other antibiotics on the enzymatic depolymerization of PHB was examined. The most potent inhibitors were polymyxin B, tyrocidine, and gramicidin D. These polypeptide antibiotics are known to attack other types of membranous structures. The results, therefore, support previous evidence that the membrane or similar constituents of PHB granules are intimately involved in its metabolism. Chlortetracycline was also found to be a potent inhibitor of the depolymerization, but its mechanism of action may be different from the other antibiotics. The polymer-synthesizing enzyme(s), also localized on the granules, is inhibited by tyrocidine and gramicidin D but not by polymyxin B or chlortetracycline. PMID- 4284919 TI - Short term parent-group education. PMID- 4284920 TI - Training supervisors as a prelude to training attendants. PMID- 4284921 TI - A voice in the people's choice. PMID- 4284922 TI - Anger in group therapy. PMID- 4284923 TI - The "average" nurse in the "average" mental hospital. PMID- 4284924 TI - Adolescent monologue. PMID- 4284925 TI - The nursing care of an emotionally disturbed child. PMID- 4284926 TI - Exercise. PMID- 4284927 TI - [Silica gel as the carrier in tritium labeling of cardiac glycosides]. PMID- 4284928 TI - Education for nursing practice. PMID- 4284929 TI - The challenge of metastatic ovarian carcinoma. PMID- 4284930 TI - [Morphology of the Welchia perfringens bacteriophage 80]. PMID- 4284931 TI - [Studies on virus-chromosome relationships. 3. Morphological transformations of adult hamster cells with and without SV 40 virus]. PMID- 4284932 TI - [On the mechanism of increased ketogenesis. II. Redox status of DPN in isolated rat liver during perfusion with fatty acids]. PMID- 4284933 TI - A correlation between the operative findings in cervical herniated discs with the electromyograms and opaque myelograms, with particular reference to simulators of root compression. PMID- 4284934 TI - [Demonstration of a ribonucleic acid of very high molecular weight in the avian myeloblastosis virus]. PMID- 4284935 TI - Evaluation of hydrolytic products of 17-ketosteroids by means of gas-liquid chromatography. PMID- 4284936 TI - Steroid production by incubated mouse adrenals. II. Control of steroid output. PMID- 4284937 TI - [Zollinger-Ellison syndrome. Presentation of a case of non-beta-cell adenoma in a heterotopic pancreas with duodeno-jejunal peptic ulceration]. PMID- 4284938 TI - [How to localize a lesion at the level of the brachial plexus]. PMID- 4284939 TI - [Treatment of traumatic lesions of the brachial plexus]. PMID- 4284940 TI - Effect of pituitary hormones on hepatic nicotinamide deamidase activity in hypophysectomized rats. PMID- 4284941 TI - The cleavage of bile acid conjugates by cell-free extracts from Clostridium perfringens. PMID- 4284942 TI - [Effect of radiations in vitro on human and rat blood platelets]. PMID- 4284943 TI - Clinico-pathologic correlation in early diagnosis of chorionic malignancy following hydatidiform mole. PMID- 4284944 TI - [The internist]. PMID- 4284945 TI - [Clinical studies of the memory. Introduction and methodology]. PMID- 4284946 TI - [Amnesic syndrome in alcoholics]. PMID- 4284947 TI - [Amnesic syndrome in head injuries]. PMID- 4284949 TI - [Apropos of hypochromic anemia in adults]. PMID- 4284948 TI - [The story of the lion. (Considerations on deviation)]. PMID- 4284950 TI - [Apropos of diffuse interstitial fibrosis of the lung]. PMID- 4284951 TI - [Use of hydroxychloroquinoline in the treatment of diarrheas of varied etiology]. PMID- 4284952 TI - [Myopathy caused by corticoids]. PMID- 4284953 TI - [Spondylodiskitis due to common bacteria]. PMID- 4284954 TI - [Fatigue fractures]. PMID- 4284955 TI - [Tuberculosis in the aged. (From the viewpoint of an internal medicine department)]. PMID- 4284956 TI - [Urinary syndrome revealing Crohn's disease]. PMID- 4284957 TI - [Reasonable limits of surgical indications in cutaneous angiomas]. PMID- 4284959 TI - Clinicopathologic conference. PMID- 4284958 TI - Peripheral nerves of the forearm and hand--their repair and regeneration. PMID- 4284960 TI - [On an unusual case of muscular involvement in a highly vascularized histiocytoma (myo-histiocytoma)]. PMID- 4284961 TI - The intestinal flora in pigs with parakeratosis. V. PMID- 4284962 TI - Drug-induced cytochemical changes in a glioblastoma. PMID- 4284963 TI - Functioning pancreatic islet-cell adenoma diagnosed preoperatively by means of splanchnic arteriography. PMID- 4284964 TI - [Pleomorphic adenomas(so-called mixed tumors) outside the large salivary glands]. PMID- 4284965 TI - [Pleomorphic adenoma of the external auditory canal]. PMID- 4284966 TI - [On the problem of semimalignancy in mixed tumors of the large salivary glands]. PMID- 4284967 TI - Phospholipids and active sodium transport in toad bladder. PMID- 4284968 TI - Metabolism of phospholipids. IX. Phosphatidate phosphohydrolase in rat liver. PMID- 4284969 TI - [Observations on the Aedes (Aedimorphus) of Africa with description of 2 new species: Ae. lottei n. sp. and Ae. dialloi n. sp]. PMID- 4284970 TI - Incidence of intestinal amoebiasis. PMID- 4284971 TI - Detection of viruslike particles in germ-free mice. AB - Kajima, Masahiro (University of Notre Dame, Notre Dame, Ind.), and Morris Pollard. Detection of viruslike particles in germ-free mice. J. Bacteriol. 90:1448-1454. 1965.-Viruslike particles similar in structure to the mouse leukemia agent were detected by electron microscopy in thymus tissues of germ free AK mice which had developed spontaneous leukemia. In addition, unique viruslike particles (type B) were detected in tissues from spontaneous mammary adenocarcinoma of germ-free C3H mice. Leukemia virus-like particles were also observed in the thymuses of the control AK mice and of the C3H control mice as well as of those with mammary tumors. Germ-free mice are not virus-free. The routes of transmission of leukemia as well as of mammary tumor viruses may be "vertical," through the embryo or placenta. PMID- 4284972 TI - Quinone-independent reduction of cytochrome b-1 by reduced nicotinamide adenine dinucleotide in a purified soluble system from Escherichia coli. PMID- 4284973 TI - [The tarsal tunnel syndrome]. PMID- 4284974 TI - Hepatoma metastasizing to the esophagus. PMID- 4284975 TI - [Perchloric acid titrations of nitrates in non-aqueous solution]. PMID- 4284976 TI - [Reflections on the place of biology in the modern world]. PMID- 4284977 TI - [The asthenias of atypical tuberculosis]. PMID- 4284978 TI - [Hypertrophic stenosis of the pylorus in infants]. PMID- 4284979 TI - [Contribution of electrophoresis technics to the diagnosis of dysglobulinemia]. PMID- 4284980 TI - [Plantar warts and radiotherapy]. PMID- 4284981 TI - [Studies on virus-chromosome relationships. V. The karyotype of the domestic rabbit]. PMID- 4284982 TI - Renal pressor material in various hypertensive diseases. PMID- 4284983 TI - [Palliative treatments of traumatic lesions of the brachial plexus]. PMID- 4284984 TI - [Voluminous tumor of the parotid gland]. PMID- 4284985 TI - The effects of varying doses of angiotensin on renal function and blood pressure in man and dogs. PMID- 4284986 TI - [Peripheral neruologic accidents of hemophilia]. PMID- 4284987 TI - Univalent fragments of antibody: a study by electron microscopy. PMID- 4284988 TI - [A technical detail on the injection of intrasinusal opaque liquid]. PMID- 4284989 TI - [Serious sequelae and complications of burns of the lower extremity]. PMID- 4284990 TI - A pharmacoangiographic method for improving nephrophlebography. PMID- 4284991 TI - Calcification in liver metastases from neuroblastoma. PMID- 4284992 TI - [Phosphate therapy in urolithiasis]. PMID- 4284993 TI - Testicular androgen biosynthesis following corticotrophin and human chorionic gonadotrophin administration. PMID- 4284994 TI - Trachoma and follicular conjunctivitis in children. PMID- 4284995 TI - Interaction of macroions with the respiratory chain system of mitochondria and heart-muscle particles. PMID- 4284996 TI - Glucose-6-phosphatase in human jejunal mucosa properties demonstrating the specific character of the enzyme activity. PMID- 4284997 TI - Conversion of fructose to glucose by human jejunum absence of galactose-to glucose conversion. PMID- 4284998 TI - 2-phosphoglyceric acid phosphatase: identification and properties of the beef liver enzyme. PMID- 4284999 TI - [Regulation of the biosynthesis and function of D- and L-lactate dehydrogenases in Aerobacter aerogenes]. PMID- 4285000 TI - Effect of periodic dialysis on the peripheral neuropathy of end-stage renal failure. PMID- 4285001 TI - [Effect of ACTH and cortisone on the capillary resistance in animals]. PMID- 4285002 TI - [On the effect of dithiocarbamic acid derivatives on the enzymatic activity of cytochrome oxidase, succinic dehydrogenase and catalase]. PMID- 4285003 TI - Hormone structure and biological activity. Biochemical studies of three pituitary hormones. PMID- 4285004 TI - [Phosphatases in pleural effusions of various character. Their significance in cancer of the prostate]. PMID- 4285005 TI - Lack of correlation between body weight and cortisol secretion, and between adrenal weight and cortisol secretion in the dog. PMID- 4285006 TI - Conservative surgical management of chorioadenoma destruens. PMID- 4285007 TI - [Secreting pancreatic tumor (insuloma)]. PMID- 4285008 TI - Pseudolipoma of the breast: a mask for cancer. PMID- 4285009 TI - Manifestations of adrenal cortical carcinoma with high oestrogen excretion. PMID- 4285010 TI - [Evaluation of the methods of determination of ACTH activities in human blood]. PMID- 4285011 TI - Dihydronicotinamide-adenine dinucleotide (NADH2) diaphorase, thiamine pyrophosphatase and acid phosphatase in the spinal cords of rabbits with chronic manganese poisoning. PMID- 4285012 TI - Effects of infusion of catecholamines and angiotensin II on renin release in anesthetized dogs. PMID- 4285013 TI - Recurrent peptic ulceration associated with pancreatic lesions (Zollinger-Ellison syndrome). Case report. PMID- 4285014 TI - A direct photometric method for chloride in biological fluids, employing mercuric thiocyanate and perchloric acid. PMID- 4285015 TI - Sex difference in rat liver uric acid metabolism. PMID- 4285016 TI - ACTH secretion in midbrain-transected rats. PMID- 4285018 TI - Genetic influence of the Rs locus on susceptibility to avian tumor viruses. I. Neoplasms induced by RPL-12 and three strains of Rous sarcoma virus. PMID- 4285017 TI - Further studies on the fractionation of human pituitary glands. PMID- 4285019 TI - Availability of niacin in wheat for swine. PMID- 4285020 TI - Enzyme histochemistry of gastric carcinoma. PMID- 4285021 TI - Pathogenesis of renal tubular necrosis induced by serotonin in the rat. PMID- 4285022 TI - The development of the flora of the alimentary tract in young animals. PMID- 4285023 TI - [Bilateral and regressive postural paralysis of the sciatic nerve in a young vintager]. PMID- 4285024 TI - [Enteroviruses]. PMID- 4285025 TI - Arrhenoblastoma of the right ovary. Report of a case. PMID- 4285026 TI - Hydatidiform mole in a 57-year old woman. PMID- 4285027 TI - Induction of ovulation with clomiphene. Report of a study including comparison with intravenous estrogen and human chorionic gonadotrophin. PMID- 4285028 TI - The effect of total-body and partial-body irradiation on granulocytic alkaline phosphatase in the rat. PMID- 4285029 TI - Chemotherapy of advanced cancer of the cervix. Experience in 55 cases treated with cyclophosphamide. PMID- 4285030 TI - [Apropos of 3 recent cases of arrhenoblastoma]. PMID- 4285031 TI - The action of substituted guanidines on mitochondrial respiration and on the ADP ATP exchange reaction. PMID- 4285032 TI - Failure of FE2+-induced lipid peroxidation and swelling in the mitochondria isolated from ascites tumor cells. PMID- 4285033 TI - Mannitol-1-phosphate dehydrogenase from the extracts of Lactobacillus plantarum. PMID- 4285034 TI - Disruption of mitochondria and solubilization of cytochrome oxidase by NaOH and KOH. PMID- 4285035 TI - [Evaluation of the immunogenic capacity of the foot-and-mouth disease virus by measurement of complement fixing capacity after treatment by a fluorocarbon]. PMID- 4285036 TI - [Rhinoviruses (cold viruses)]. PMID- 4285037 TI - [A particular neurologic syndrome after cervical adenopathy exeresis. 4 cases]. PMID- 4285038 TI - [Data on the phosphatases in veterinary medicine]. PMID- 4285039 TI - [Preliminary observations concerning the use of a synthetic delayed-action corticostimulin derivative (CIBA 36.716-Ba) in patients with asthma]. PMID- 4285040 TI - Typing of the foot-and-mouth disease virus. PMID- 4285041 TI - Malignant non-chromaffin paraganglioma (report of two cases). PMID- 4285042 TI - The control of inhibitory impurities in reduced nicotinamide adenine dinucleotide in lactate dehydrogenase assays. PMID- 4285043 TI - Persistence as a motivator. PMID- 4285044 TI - [Clinical picture of primary malignant tumors of the liver in children]. PMID- 4285045 TI - [Studies on circulation of enterovirus in samples of the population subjected to oral antipoliomyelitis vaccination]. PMID- 4285046 TI - [Demonstration of a factor capable of interfering with the poliomyelitic virus in renal cultures of monkeys infected with the measles virus (Biseci strain). Effect of treatment with beta-propiolactone]. PMID- 4285047 TI - [The practical value of acetic anhydride in perchloric acid titration and its identification in acetic acid]. PMID- 4285048 TI - Encephalitis associated with herpes simplex virus. PMID- 4285049 TI - Herpes simplex encephalitis. Report of 20 cases. PMID- 4285050 TI - [The perchlorate test in semeiology of thyroid diseases due to oxidase enzymopenia]. PMID- 4285051 TI - Immunochemical study on antigenic components of Borketella pertussis. PMID- 4285052 TI - Studies on protective antigen of Bordetella pertussis: isolation of protective antigen by sucrose density gradient centrifugation and some properties of the antigen. PMID- 4285053 TI - On the relationship between histamine sensitizing factor and mouse protective antigen. PMID- 4285054 TI - [The intradermal test with angiotensin II and pathogenesis of essential hypertension]. PMID- 4285055 TI - The effect of sex differences and gonadectomy on some aortic enzymes of the rat. PMID- 4285056 TI - [Influences modifying pressure reactions to exogenous angiotensin]. PMID- 4285057 TI - Cardiovascular reactivity in rats with spontaneous inherited hypertension and constricted renal artery hypertension. PMID- 4285058 TI - An evaluation of the radiotherapeutic management of intracranial glial tumors without prior surgery. PMID- 4285059 TI - Cylindroma. PMID- 4285060 TI - Radio immunoassay employing gel filtration. PMID- 4285061 TI - Determination of heme a concentration in cytochrome preparations by hemochromogen method. PMID- 4285062 TI - Ion-exchange thin-layer chromatography. XII. Quantitative elution and microdetermination of nucleoside monophosphates, ATP, and other nucleotide coenzymes. PMID- 4285063 TI - [Study, in culture, of the production of Rous virus by contact between rat XC sarcoma cells and chick embryo cells]. PMID- 4285064 TI - In vitro polio virus inhibition by two guanidino-pyrimidines. PMID- 4285065 TI - The effect of ACTH on cholinesterase activity in plasma, whole blood, and blood cells of rats. PMID- 4285066 TI - The relation between ionic fluxes and the action of drugs on smooth muscle. PMID- 4285067 TI - Gangrene of the eyelids. PMID- 4285068 TI - Comparison of the inactivation and antigenicity of foot-and-mouth-disease virus by acetylethyleneimine and by combined effect of ultraviolet light and beta propiolactone. PMID- 4285069 TI - Enterovirus hemagglutination: inhibition by several enzymes and sugars. PMID- 4285070 TI - The blocking effect of West Nile virus on production of sarcoma by Rous virus in chickens. PMID- 4285071 TI - [The renin-angiotensin system]. PMID- 4285072 TI - The role of viruses in the etiology of chromosomal abnormalities. PMID- 4285073 TI - The involvement of a tryptophan residue of glutamate dehydrogenase in the binding of L-glutamate. PMID- 4285074 TI - On the formation of thymidine-3'-triphosphate by a mammalian cell-free system. PMID- 4285075 TI - Synthesis of microsomal membranes and their enzymic constituents in developing rat liver. PMID- 4285076 TI - Labeling of mitochondrial phosphatidyl inositol phosphate by Pi32 and gamma P32ATP. PMID- 4285078 TI - Variable drug sensitivity and chromosomal features of a cancer clone. PMID- 4285077 TI - Parathyroid hormone and metastasis of experimental tumor. I. Effect of parathyroid hormone on the metastasis formation of experimental tumor. PMID- 4285079 TI - SHistochemical studies on beta-glucuronidase in normal and abnormal tissues employing naphthol AS-OL glucuronide as a substrate. PMID- 4285080 TI - Infection of tumor cells by extraneous viruses. 3. Viral infection of tumors in homologous and heterologous hosts. PMID- 4285081 TI - Base composition of RNA in hepatic subcellular fraction from rats fed carcinogenic aminoazo dye. PMID- 4285083 TI - Activated silica gel as an adsorbent for atmospheric contaminants. PMID- 4285082 TI - Handling of perchloric acid in laboratories and fume cupboards. PMID- 4285084 TI - [The major diabetic syndromes]. PMID- 4285085 TI - [The antidiabetic drugs]. PMID- 4285086 TI - [Treatment of the major diabetic syndromes]. PMID- 4285087 TI - [Primary hyperaldosteronism treated surgically]. PMID- 4285088 TI - [Trial of a hexachlorophene emulsion in preoperative skin preparation]. PMID- 4285089 TI - [The hemodynamic consequences of heterotopic tachycardia and auricular fibrillation]. PMID- 4285091 TI - [Death in myocardial infarct]. PMID- 4285090 TI - [The vulnerable period and ventricular fibrillation]. PMID- 4285092 TI - [Transmembrane ion exchange during the cardiac cycle]. PMID- 4285093 TI - [Schwannosarcoma of the small intestine]. PMID- 4285094 TI - [Purulent Moraxella meningitis treated by a new delayed-action sulfonamide (sulfamethomidine). Recovery]. PMID- 4285095 TI - [Schizophrenia. Current clinical data and discussions]. PMID- 4285096 TI - [Atypical forms of Klinefelter's disease]. PMID- 4285097 TI - [Basedow's disease in men. Comparative study of 200 male cases and 200 female cases]. PMID- 4285098 TI - [Discontinuous ventilatory assistance in the treatment of diffuse obstructive emphysema]. PMID- 4285099 TI - [Clinical and biological results obtained with a new diuretic derived from 2,4,7 triaminopteridine]. PMID- 4285100 TI - Induction of cellular DNA synthesis by polyoma virus. II. Increase in the rate of enzyme synthesis after infection with polyoma virus in mouse kidney cells. PMID- 4285101 TI - Purification and chemical analysis of Shope papilloma virus. PMID- 4285102 TI - A heat-sensitive cellular function required for the replication of DNA viruses but not RNA viruses. PMID- 4285103 TI - Virus particles associated with "nonproducer" Rous sarcoma cells. PMID- 4285104 TI - Cytological observations of "nonproducer" Rous sarcoma cells. PMID- 4285105 TI - A cause of variation in clonal morphology of polyoma transformed hamster cells. PMID- 4285106 TI - Partial nucleotide sequences in turnip yellow mosaic virus RNA. PMID- 4285107 TI - Infectious poliovirus RNA: a sensitive method of assay. PMID- 4285108 TI - Induction of SV40 T antigen with SV40 DNA. PMID- 4285109 TI - Enhanced thymidine kinase activity following infection of green monkey kidney cells by simian adenoviruses, simian papovavirus SV40, and an adenovirus-SV40 "hybrid". PMID- 4285110 TI - [A new method for the elimination of water with strong cyanide content in a cokery]. PMID- 4285111 TI - [Polyglobulism during primary hepatoma with cirrhosis]. PMID- 4285112 TI - [Influence of various chemical modifications on the capacity of s-RNA to refix its terminal pCpCpA triplet]. PMID- 4285113 TI - A survey of enteroviruses and adenoviruses in the faeces of normal children aged 0-4 years. A report of the Public Health Laboratory Service and the Society of Medical Officers of Health. PMID- 4285114 TI - Infections acquired in medical wards. A report from the Public Health Laboratory Service. PMID- 4285115 TI - The effect of intra-arterial hydrogen peroxide in rabbits infected with Clostridum perfringens. PMID- 4285117 TI - Curriculum, thy name is change. PMID- 4285116 TI - Virilizing adrenal tumors in childhood. Report of a case. PMID- 4285119 TI - Emergency a la carte to table d'hote. PMID- 4285118 TI - There is a difference. PMID- 4285120 TI - Study to seek ways to meet rural nurse shortage. PMID- 4285122 TI - SJH family centered maternity care based on naturalness, togetherness. PMID- 4285121 TI - The bridge between protected student and productive graduate. PMID- 4285124 TI - [Wilms' tumors]. PMID- 4285123 TI - [Experimental data on the problem of treating hyperthyroidism with ACTH and glycocorticoids]. PMID- 4285125 TI - Cystosarcoma phyllodes: a review of three cases. PMID- 4285126 TI - Surgical treatment of hyperinsulinism due to B-cell adenoma. PMID- 4285127 TI - [Changes in the gill epithelium of goldfish caused by silicic acid]. PMID- 4285128 TI - [Changes in the levels of plasma 17-hydroxycorticosteroids and blood 17 ketosteroids during adrenocorticotrophic hormone intravenous perfusion before and after adrenosplenic transplantation and right adrenalectomy in patients with advanced breast cancer]. PMID- 4285129 TI - [Isolation of a ribonucleic acid of high molecular weight from 2 different Rous virus strains]. PMID- 4285130 TI - [Inhibition of the multiplication of the myeloblastosis virus (AMV) in vitro by guanidine]. PMID- 4285131 TI - [Suppression by spirolactones of the natriuretic effect of angiotensin peculiar to certain cirrhotics]. PMID- 4285132 TI - Metabolism of isolated fat cells. 3. The similar inhibitory action of phospholipase C (Clostridium perfringens alpha toxin) and of insulin on lipolysis stimulated by lipolytic hormones and theophylline. PMID- 4285133 TI - Nicotinamide mononucleotide pyrophosphorylase activity in animal tissues. PMID- 4285134 TI - On the magnetic resonance of spinach ferredoxin. PMID- 4285135 TI - Structure of the chondroitin 4-sulfate-protein linkage region. Isolation and characterization of the disaccharide 3-O-beta-D-glucuronosyl-D-galactose. PMID- 4285136 TI - Enzymatic studies on isolated nucleoli of rat liver. PMID- 4285137 TI - [Contribution to the radiochemical evaluation of a new series of hydrosoluble organo-iodized contrast media]. PMID- 4285138 TI - Tracheal and tracheobronchial resections; technique and results in 20 cases. PMID- 4285139 TI - [Skeletal maturation in mongoloids]. PMID- 4285140 TI - [Influence in time of therapy with oral cortisonoids on bone growth of children with the congenital adrenogenital syndrome]. PMID- 4285141 TI - [Determination of bone age in a community of diabetic children]. PMID- 4285142 TI - Unexpected deaths from small bowel obstruction. PMID- 4285143 TI - [Extra-adrenal actions of ACTH]. PMID- 4285144 TI - [Subacute pneumophathies]. PMID- 4285145 TI - [Dysglobulinemic purpura in the course of a severe rheumatoid polyarthritis]. PMID- 4285146 TI - [Diffuse acquired pulmonary lymphangiectasis]. PMID- 4285148 TI - [Rupture of the tendinous cuff of the rotator muscles of the shoulder. Anatomical, radiological and clinical study]. PMID- 4285147 TI - [Fatal hypoglycemia due to a hypoglycemic sulfonamide in a patient with an adenoma of the adrenal cortex and renal insufficiency]. PMID- 4285149 TI - [A case of traumatic rupture of the isthmus of the thoracic aorta, operated successfully 8 hours after the accident]. PMID- 4285150 TI - [Fulminant rectocolitis with colectasis. Review of literature apropos of 4 cases]. PMID- 4285152 TI - [Hyperosmolar coma in diabetics. (Apropos of a case)]. PMID- 4285151 TI - [Farmer's lung. Apropos of 5 cases]. PMID- 4285153 TI - [False image of tumor of the greater gastric tuberosity due to voluminous varices]. PMID- 4285155 TI - [The fluctuations of concepts in cardiology]. PMID- 4285154 TI - [Therapeutic trials with methenolone in disorders of protein metabolism in patients treated by radiotherapy alone for cancers of the head and neck]. PMID- 4285156 TI - [Attempted breakdown of tuberculous rheumatism]. PMID- 4285157 TI - [Antibiotics and infection in abdominal surgery]. PMID- 4285158 TI - [Spontaneous mediastino-subcutaneous emphysema and simultaneous bilateral pneumothorax during an infectious syndrome of influenzal appearance]. PMID- 4285159 TI - Recovery and identification of adenovirus in infections of infants and children. PMID- 4285161 TI - [Some characteristics of the Motol virus]. PMID- 4285160 TI - Recovery and identification of human myxoviruses. PMID- 4285162 TI - [A patient with a very small ovarian tumor]. PMID- 4285163 TI - Hereditary compression syndrome of peripheral nerves. PMID- 4285164 TI - The effect of stimulus intensity on latency of nerve action potential in healthy subjects and in patients with peripheral nerve lesions. PMID- 4285165 TI - [Study, using metopirone (SU 4885), of the relation between cortisol production and adrenocorticotropin secretion]. PMID- 4285166 TI - [Use of a fluorocarbon as a method of study of the aphthous fever virus]. PMID- 4285167 TI - The clinical management of peripheral pain. PMID- 4285168 TI - Multiple inhibition of yeast alcohol dehydrogenase. PMID- 4285169 TI - Hydrophobic interactions in the binding of nicotinamide adenine dinucleotide to yeast alcohol dehydrogenase. PMID- 4285170 TI - A "three gases technique" as a method for the determination of volatile hydrides and related compounds in a modified Warburg assay. PMID- 4285171 TI - Vitamin D-3-sensitive Ca-45 binding by microsomal preparations from chick intestinal mucosa. PMID- 4285172 TI - Myeloperoxidase of the leucocyte of normal human blood. 3. Isolation of the peroxidase granule. PMID- 4285173 TI - [Nursery school epidemic caused by adenovirus 7]. PMID- 4285174 TI - [Fatal adenovirus pneumonia in infancy. Report on 2 of our own cases]. PMID- 4285175 TI - [Skeletal age in children with cerebral palsy]. PMID- 4285176 TI - Effect of corticotropin on the absorption of vitamin B12 in the subacute combined degeneration of the spinal cord. PMID- 4285177 TI - Age changes in certain properties of the DNA of the small intestinal mucosa of white rats. PMID- 4285178 TI - Structural and cytochemical organization of receptor cells of the sense organs in the light of their functional evolution. PMID- 4285179 TI - Effect of repeated ACTH administration on 3-beta-ol-dehydrogenase activity and synthesis of steroids from progesterone in adrenal glands of rabbits. PMID- 4285180 TI - The biosynthesis of adrenal steroids: effects of angiotensin II, adrenocorticotropin, and potassium. PMID- 4285181 TI - [Dean Gaston Cordier]. PMID- 4285182 TI - [Pulmonary tuberculosis with resistant bacilli in untreated patients]. PMID- 4285183 TI - [Bronchopulmonary infections and disorders of the left heart]. PMID- 4285184 TI - [Clinical and electroencephalographic evolution of subdural hematoma in infants. (Apropos of 45 cases)]. PMID- 4285185 TI - [Thrombocytopenic purpura in the course of an icterogenic hepatitis]. PMID- 4285186 TI - [Extrapancreatic tumors causing hypoglycemia]. PMID- 4285187 TI - [Study of the pituitary-adrenocortical activity in cirrhotics. (Tests of stimulation by ACTH and metopyrone)]. PMID- 4285188 TI - [Allergy to quaternary ammonium salts]. PMID- 4285189 TI - [Indications and immediate risks of terminolateral portacaval anastomosis in cirrhotics. Based on a series of 100 PCA's performed between 1959 and 1964]. PMID- 4285190 TI - [Remarks on the problems caused by biliary sepsis in extrahepatic bile duct surgery and its effect on blood coagulation]. PMID- 4285191 TI - [Isolated diverticulum of pseudotumoral form in the ascending cecum due to intradiverticular stercoroma]. PMID- 4285192 TI - [Study of ornithine carbamoyltransferase in light hepatic attacks and the sequelae of hepatitis]. PMID- 4285193 TI - [Experimental study of the induced blood alcohol test in chronic alcoholic mental patients]. PMID- 4285194 TI - [Thrombocythemias. (Apropos of 11 cases). I. Etiologic, symptomatic and therapeutic study]. PMID- 4285195 TI - [Thrombocythemias. (Apropos of 11 cases). II. Study of hemostatic functions]. PMID- 4285196 TI - [Diagnosis and treatment of tumors of the thyroid body. Role of radioactive iodine]. PMID- 4285197 TI - [Hyperlipemias]. PMID- 4285198 TI - [Therapeutic indications in peripheral facial paralysis]. PMID- 4285199 TI - [Pericardial effusions due to thyroid insufficiency. Apropos of 3 cases]. PMID- 4285200 TI - [The desferrioxamine B induced hypersideruria test in hemochromatosis]. PMID- 4285201 TI - ["Serratia marcescens" septicemia]. PMID- 4285202 TI - [Therapeutic trials in rheumatology of an aspirin-prednisone-vitamin B complex combination]. PMID- 4285203 TI - [Early changes in the blood serum, hemogram and blood glucose level in donors after donation with special reference to general adaptation syndrome]. PMID- 4285204 TI - Magnetic and optical properties of some bacterial haem proteins. PMID- 4285205 TI - Oxygen evolution coupled to reduction of manganipyrophosphate ion by illuminated spinach chloroplasts. PMID- 4285206 TI - Magnetic anisotropy of the myoglobin single crystal. PMID- 4285207 TI - Electron spin resonance of haemoglobin MIwate and MOsaka. PMID- 4285208 TI - Studies on the mechanism of antiviral activity of ketoaldehyde derivatives of biphenyl. PMID- 4285209 TI - The interaction of free radicals in protein and melanin. PMID- 4285210 TI - Phosphatase activity during the growth and metamorphosis of Tribolium confusum Duval. PMID- 4285211 TI - Studies on human platelet granules and membranes. PMID- 4285212 TI - Absorption of vitamin D3-3H in control subjects and patients with intestinal malabsorption. PMID- 4285214 TI - [Severe accidents related to the use of iodized contrast media in the radiologic exploration of the urinary system]. PMID- 4285213 TI - [Apropos of hepatographies observed in the course of lymphographies]. PMID- 4285215 TI - [Oral metastasis from a Wilms' tumor]. PMID- 4285216 TI - Immunological studies of human gliomas. PMID- 4285218 TI - [Congenital hepatic hemangiomatosis. Clinical and scintigraphic study of a case with a favorable outcome]. PMID- 4285217 TI - Perchlorate test in hyperthyroid patients treated with radioactive iodine. PMID- 4285219 TI - [Carcinoid syndrome and cardiopathy. A further case and review of the literature]. PMID- 4285220 TI - [Cancers of the gastric stump]. PMID- 4285221 TI - [Anatomical study of the liver in severe denutrition]. PMID- 4285222 TI - [Clinical, metabolic, hormonal and anatomic study of a case of paraneoplastic hypercorticism revealing a thyroid cancer]. PMID- 4285223 TI - [Recurring mitral stenosis. Clinical signs and anatomical lesions]. PMID- 4285224 TI - [Treatment of leprosy with long-acting sulfonamides]. PMID- 4285225 TI - ["Every man is a sacred story"]. PMID- 4285226 TI - [The physician and the death penalty]. PMID- 4285227 TI - [Marat, a lover of justice or delirious?]. PMID- 4285228 TI - [Morphologic and serologic evaluation of the reaction to smallpox revaccination with special reference to virus neutralizing antibodies]. PMID- 4285229 TI - Encephalitis associated with adenovirus type 7 occurring in a family outbreak. PMID- 4285230 TI - Bilateral mixed tumors of the palate. PMID- 4285231 TI - Retinal disease in neurology. PMID- 4285232 TI - Hamster ascitic fluids containing complement-fixing antibody against virus induced tumor antigens. PMID- 4285233 TI - Simian enterovirus SV2 hemagglutination studies. II. Effect of various treatments on the hemagglutinin and its cell receptors. PMID- 4285235 TI - Responses of cell cultures to insecticides. 3. Altered susceptibility to poliovirus and diphtheria toxin. PMID- 4285234 TI - Inhibition of Sendai virus by N-1-isobutylbiguanide hydrochloride as studied by immunofluorescent staining. PMID- 4285236 TI - Effects of oophorectomy and various doses of estradiol-17beta on corticosterone production by rat adrenal slices. PMID- 4285237 TI - Thymidine kinase in IDU resistance. PMID- 4285238 TI - Succinoxidase activity of the liver of rats bearing Walker carcinoma 256. PMID- 4285239 TI - Sodium and potassium intake, blood pressure, and pressor response to angiotensin. PMID- 4285240 TI - Distribution of vitamin D3-4c14 in rachitic and vitamin D3 treated chicks. PMID- 4285241 TI - Pathogenicity of murine hepatitis virus recovered from infant Swiss mice. PMID- 4285242 TI - Zoster-like lesions from herpes simplex virus in newborn rats. PMID- 4285244 TI - Generalized infantile herpes simplex. Report of an autopsy case with special reference to its relationship to Kaposi's varicelliform eruption. PMID- 4285243 TI - Spontaneous leukemia in germfree AK mice. PMID- 4285245 TI - Effects of norepinephrine and angiotensin II-amide on coronary flow and myocardial oxygen consumption in the cat. PMID- 4285246 TI - Skeletal development of cleft palate children as determined by hand-wrist roentgenographs: a preliminary study. PMID- 4285247 TI - [Isolation and typing of enteroviruses in 72 cases of paralytic poliomyelitis and 12 cases of aseptic meningitis]. PMID- 4285248 TI - [Cylindroma of the soft palate]. PMID- 4285249 TI - Glucocorticoids for parenteral administration. PMID- 4285250 TI - Physiological and patho-physiological variations, relation to pituitary adrenocortical hormones, and to serum trypsin inhibitor. PMID- 4285251 TI - Effect of phosphate on the activity of NADH-diaphorase from erythrocytes of hereditary methemoglobinemia. PMID- 4285252 TI - Studies of adenovirus SV40 hybrid viruses. I. Assay system and further evidence for hybridization. AB - The titers of adenovirus and SV40 genetic carriers in hybrid preparations (E46(+)) can be quantitated by determining the percentage of cells showing neoantigens stainable with fluorescent antibody (FA) at 21 to 24 hours; both titers can be obtained with a single coverslip. The adenovirus and SV40 antigen inducing titers so obtained are of the same order of magnitude in stock preparations of E46(+) grown in either African green monkey kidney (AGMK) or human embryonic kidney tissue culture (HEK), and are generally within one log of the infectivity titer. Quantitative studies of 50 degrees C heat inactivation, ultracentrifugation, and equilibrium density gradient centrifugation of E46(+) gave no indication that SV40 neoantigen induction could be dissociated from adenovirus, whereas adenovirus and SV40 virus grown as a mixed infection were readily dissociated by these procedures. Pretreatment of HEK cells with a medium containing 5-fluorouracil desoxyriboside (FUDR) did not affect induction of either adenovirus or SV40 neoantigen or development of cytopathic effects after infection with E46(+), but did prevent formation of Ad. 7 viral antigen. PMID- 4285253 TI - Studies of adenovirus SV40 hybrid viruses. II. Defectiveness of the hybrid particles. AB - E46(+) virus purified by limiting dilution and plaque isolation in AGMK cells consists of a mixture of hybrid and non-hybrid virus particles. Of 102 plaque isolates obtained in HEK cells, 98 contained no detectable hybrid virus, while 4 contained a small proportion of hybrid virus. Plaque isolates from AGMK cells uniformly induced SV40 neoantigen, but when these plaque isolates were plaqued in HEK cells the progeny were again non-hybrid adenovirus. It thus appears impossible to obtain a pure line of hybrid virus. The proportion of hybrid virus produced in HEK cells fell progressively with decreasing multiplicity of infection, and plaque induction by E46(+) virus in AGMK followed 2-hit kinetics, indicating that the hybrid virus particles are defective and require dual infection with non-hybrid virus for their propagation. PMID- 4285254 TI - Studies of a myxovirus recovered from patients with infectious hepatitis. AB - A virus has been isolated from the serum and urine of patients with infectious hepatitis. This virus is a member of the parinfluenza group. It is serologically distinct from the known members of the group, but apparently is antigenically related to the simian type-2 parainfluenza viruses. A causal relationship between WB virus and infectious hepatitis has not been established. PMID- 4285256 TI - Pleomorphic adenoma of the upper lip. PMID- 4285255 TI - Primary hepatoma associated with polycythaemia: report of a case with a study of tumour and urine erythropoietin levels. PMID- 4285257 TI - The effect of certain hemostatic agents and the local use of diluted epinephrine on bleeding during oral surgical procedures. PMID- 4285259 TI - Cardiovascular drugs in muscular subaortic stenosis. PMID- 4285258 TI - Bronchiolar carcinoma: a report of six cases. AB - Bronchiolar carcinoma is a malignant tumour which apparently arises in a terminal bronchiole from which it spreads either by bronchial embolization or by lymphogenous and/or hematogenous dissemination. It is not a common neoplasm.Histologically, the tumour bears a striking resemblance to the disease of sheep, jagziekte, which is of virus etiology. A very common finding in reported cases is preexisting pulmonary fibrosis. At the Nova Scotia Sanatorium, Kentville, 80 cases of primary lung cancer have been encountered within the past 25 years. Six of these were bronchiolar carcinomas. Five patients had co-existing chronic pulmonary disease, bronchiectasis in one and tuberculosis in four. One patient died of a rapidly progressive bilateral lesion and five were explored. Lobectomy was done in all five, but in one for palliation only. Three patients are alive and well three, six and 14 years, respectively, after their operations. PMID- 4285260 TI - Retroperitoneal nonchromaffin paraganglioma with hormonal activity. PMID- 4285261 TI - Studies on the development, biochemistry, and biology of experimental hepatomas. PMID- 4285262 TI - Avian tumor viruses. PMID- 4285263 TI - Angiotensin and the liver. PMID- 4285264 TI - Cardiovascular responses of the primate in endotoxin shock. PMID- 4285265 TI - Factors affecting antibody transfer in the newborn puppy. PMID- 4285266 TI - Effects of prolonged heat exposure on the cellular metabolism of the hamster. PMID- 4285267 TI - [Tarsal tunnel syndrome and subcalcaneal exostosis]. PMID- 4285268 TI - [Presence of rheumatoid factors in antibacterial horse immune sera]. PMID- 4285269 TI - [On granular cell myoblastomyoma]. PMID- 4285270 TI - Angiotensin. PMID- 4285271 TI - [Glomus jugulare tumor with parotid extension]. PMID- 4285272 TI - The periodate-Schiff reaction: specificity, kinetics, and reaction products with pure substrates. PMID- 4285273 TI - Pulmonary cancer and adenomatosis in captive wild mammals and birds from the Philadelphia zoo. PMID- 4285274 TI - Nasopharyngeal angiofibroma: (a report of 21 cases treated surgically). PMID- 4285275 TI - [From diarrhea caused by immune globulin deficiency to protein-losing enteropathies. Physiopathological study]. PMID- 4285276 TI - [Disorders of calcium and phosphorus metabolism in myeloma of bone]. PMID- 4285277 TI - Elevation of erythropoietin levels in association with Wilms' tumor. PMID- 4285278 TI - Thrombotic thrombocytopenic purpura. Recovery after splenectomy. PMID- 4285279 TI - Formation of oligonucleotides with 5'-phosphomonoester end group by rat-liver microsomal fraction. PMID- 4285280 TI - Ryan virus: a possible new human pathogen. PMID- 4285281 TI - Leukaemia and neoplastic processes treated with Langat and Kyasanur Forest disease viruses: a clinical and laboratory study of 28 patients. PMID- 4285282 TI - Non-specific effects of synthetic corticotrophin polypeptides. PMID- 4285283 TI - Parotid fluid steroid responses to ACTH in surgically confirmed cases of Cushing's syndrome. PMID- 4285284 TI - ACTH-like activity in a thymoma associated with gonadal dysgenesis. PMID- 4285285 TI - Glucocorticoid suppression of urinary testosterone excretion in patients with idiopathic hirsutism. PMID- 4285287 TI - Tumors in newborn animals. PMID- 4285286 TI - Deoxycorticosterone acetate hypertension in dogs. PMID- 4285288 TI - [Determination of ACTH reserve in endocrinologic and cirrhotic patients by the metopirone test]. PMID- 4285289 TI - Results in the treatment of Wilms' tumour. PMID- 4285290 TI - Response of tumorigenic viruses and of cells to biologically active compounds. I. Methods for determining response and application of methods. PMID- 4285291 TI - The effect of age on the variations in the activities of glucose-6-phosphatase and fructose-1,6-diphosphatase in the liver of chicks. PMID- 4285292 TI - Effect of cocaine on cardiovascular responses in intact dogs. PMID- 4285293 TI - [Experimental chronic interstitial pyelonephritis with atrophic kidneys in mice after injection of acellular tumor filtrates]. PMID- 4285294 TI - [Primary muciparous tumors of the bronchi]. PMID- 4285295 TI - [On the effect of heparin treatment on the elimination of single 17-ketosteroid fractions]. PMID- 4285296 TI - [Aftereffects of long-time administration of ACTH on the function of the hypophyseal and adreno-cortical system in the guinea pig]. PMID- 4285297 TI - Spontaneous herpes-T infection in the owl monkey (Aotus trivirgatus). PMID- 4285298 TI - [Hidradenoma of the vulva]. PMID- 4285299 TI - Adrenaline synthesis: control by the pituitary gland and adrenal glucocorticoids. AB - The activity of phenylethanolamine-N-methyl transferase, an enzyme that synthesizes adrenaline from noradrenaline in the adrenal medulla, is markedly depressed following hypophysectomy. Enzyme activity is restored to normal after administration of ACTH or the potent glucocorticoid, dexamethasone. Thus the biosynthesis of adrenaline in the adrenal medulla appears to be regulated by the pituitary-adrenocortical system. PMID- 4285300 TI - Biosynthess of histones and acidic nuclear proteins under different conditions of growth. AB - The incorporation of uniformly labeled L-lysine-C(14) into the normal and regenerating rat liver, into Novikoff hepatoma histones, and into acidic nuclear proteins was studied. In rat liver, different histone fractions incorporate labeled lysine to a different extent. Such differences become less obvious in regenerating liver, and they are even less so in Novikoff hepatoma. In the hepatoma cells the ratio of the biosynthesized acidic nuclear proteins to histones was altered. PMID- 4285301 TI - [Acute bronchiolitis in infants. Isolation of para-influenza type 3 virus]. PMID- 4285302 TI - Effect of sympathomimetic amines and angiotensin on active ion transport in smooth muscles. PMID- 4285303 TI - A study by interference microscopy of the qualitative and quantitative changes in Entamoeba histolytica under different experimental conditions. PMID- 4285304 TI - Further studies on the deletion of the cholesterol feedback system in hepatomas. PMID- 4285305 TI - On protein binding of fluorenyl carcinogens by minimal deviation hepatomas. PMID- 4285306 TI - [Active immunization against an infection caused by the B virus (Herpesvirus simiae). I. Experience with the preparation and evaluation of Hull's formaldehyde vaccine]. PMID- 4285307 TI - A calcifying topical reaction to mast cell depletors in the rat. PMID- 4285308 TI - [Use of hypertensin in the treatment of shock in myocardial infarct]. PMID- 4285309 TI - Experimental bacterial peritonitis in mice. PMID- 4285310 TI - The fine structure of the normal, neonatal mouse liver. PMID- 4285311 TI - [Listeriosis and cytomegaly as causes of intrauterine infection]. PMID- 4285312 TI - [Apropos of the management of chemodectoma of the ear]. PMID- 4285313 TI - [Value of radiologic examination in the detection of hepatoblastoma]. PMID- 4285314 TI - [Study of age distribution of neutralizing antibodies against herpes simple virus in Sao Paulo]. PMID- 4285316 TI - On the etiology of recurring oral ulcers. PMID- 4285315 TI - [Transmission in vitro to normal chicken cells of a specific antigen by association with rat tumor cells induced by Rous sarcoma virus]. PMID- 4285317 TI - [Excretion of metabolites of the adrenal cortex during treatment of adnexitis with glycocorticoids]. PMID- 4285318 TI - The induction of mammary growth in the hypophysectomized goat. PMID- 4285319 TI - [On two fatal cases of lung disease correlated with Adenovirus type 7]. PMID- 4285320 TI - [Demonstration of immunological differences between Graffi- and Gross-virus induced mouse leukemias in vivo and in vitro]. PMID- 4285321 TI - Neoplastic transformation of rat embryo fibroblasts by fowl sarcoma virus B77. PMID- 4285322 TI - [Mesenchymal tumor, langerhansian adenoma and hypoglycemic complications]. PMID- 4285324 TI - [Cardiovascular diseases in aged subjects. Results of a morbidity survey in an old age home]. PMID- 4285323 TI - Drug combinations in antibacterial chemotherapy. AB - DOUBLE CHEMOTHERAPY FOR THE TREATMENT OF BACTERIAL INFECTIONS HAS BEEN RECOMMENDED FOR MANY REASONS, OF WHICH THE MOST IMPORTANT ARE THE FOLLOWING: (1) To achieve a synergic effect. (2) To delay the emergence of resistant strains. (3) To prevent superinfection. (4) To treat relatively inaccessible bacteria. (5) To treat mixed infections. (6) To treat undiagnosed infections.Combinations which have a truly synergic effect in vivo are those which show bactericidal synergy in vitro. Bactericidal therapy is of great practical importance in conditions which are inaccessible to the natural defences of the body, or where they are deficient. If in such cases the infecting bacterium is not readily killed by a single drug, then combinations should be tried. There are no absolute rules and double bactericidal sensitivity tests should always be carried out on the infecting strain, but the most likely combination to show this type of synergy is a penicillin and streptomycin.If a bactericidal drug is combined with an agent which is only bacteristatic, the killing effect may be antagonized, since many bactericidal drugs only kill rapidly multiplying cells. Again there are no absolute rules, but antagonism is particularly liable to occur when the bactericidal agent is one of the penicillins and is very unlikely to occur when it is a polymyxin, since this kills resting bacteria.Drug combinations to delay the emergence of drug-resistant strains should be considered for infections due to staphylococci and coliform bacilli, particularly in hospitals, and when it is desired to use drugs to which these bacteria readily develop resistance.Drug combinations may also be the most efficient treatment for mixed infections and may be necessary for the treatment of fulminating infections pending bacteriological diagnosis. The combination of nystatin with a tetracycline may be necessary to prevent candidiasis if tetracycline therapy has to be prolonged. PMID- 4285325 TI - [328 suicide attempts observed in a general medicine department]. PMID- 4285326 TI - [History of a prolonged dysphagia. The value of transient, past and unrecongnized signs]. PMID- 4285327 TI - [Major left ventricular insufficiency caused by uremigenic necrotico-hemorrhagic pancreatitis with electrical image of myocardial ischemia]. PMID- 4285328 TI - [Starch and iodolipol tests as indices of the exocrine pancreatic function]. PMID- 4285329 TI - [Histochemical enzyme studies and ultramicroscopic investigation of the effect of ACTH and prednisone on the kinetics of the formation of pancreatic juice in the rat]. PMID- 4285330 TI - A histochemical study of hydrolytic and oxidative enzymes in an eosinophilic granuloma of parotid gland region. PMID- 4285331 TI - Use of tetrazolium salts for electron transport studies in meningopneumonitis. I. Reduced nicotinamide adenine dinucleotide system. AB - Allen, Emma G. (Downstate Medical Center, Brooklyn, N.Y.). Use of tetrazolium salts for electron transport studies in meningopneumonitis. I. Reduced nicotinamide adenine dinucleotide system. J. Bacteriol. 90:1505-1512. 1965. Purified preparations of meningopneumonitis virus (MP) prepared from allantoic fluids of infected chick embryo reduce several tetrazolium salts in the presence of reduced nicotinamide adenine dinucleotide under both aerobic and anaerobic conditions. The pattern of reduction by MP differs from that seen in normal allantoic membrane homogenates, and is inhibited by several cations but not by KCN, atabrine, amytal, antimycin A, or 2,3-dimercaptopropanol (BAL). The reduction of cytochrome c by purified preparations of MP differs from its reduction of tetrazolium salts in that the cytochrome reaction is completely inhibited by BAL and partially inhibited by amytal, atabrine, and antimycin A. The cytochrome reductase of normal allantoic membrane preparations is completely inhibited by each of these compounds. PMID- 4285332 TI - Nucleic acid-induced resistance to viral infection. AB - Takano, Kouichi (Chas. Pfizer & Co., Inc., Terre Haute, Ind.), Joel Warren, Keith E. Jensen, and Alan L. Neal. Nucleic acid resistance to viral infection. J. Bacteriol. 90:1542-1547. 1965.-Administration of nonviral nucleic acids to mice increased their resistance to a subsequent infection with influenza or encephalomyocarditis viruses. Injection of ribonucleic acid or deoxyribonucleic acid by peripheral routes did not modify susceptibility to intranasal infection. Lung tissue extracts from animals previously treated with yeast nucleic acid inhibited the growth of vaccinia and influenza viruses. The protective effect of exogenous nucleic acids persisted in mice for several days, but gradually diminished to undetectable levels. PMID- 4285333 TI - Incorporation of C14 from amino acids and peptides into protein by Clostridium perfringens type D. AB - Hauschild, Andreas H. W. (University of Toronto, Toronto, Ontario, Canada). Incorporation of C(14) from amino acids and peptides into protein by Clostridium perfringens type D. J. Bacteriol. 90:1569-1574. 1965.-Uptake of C(14) from C(14) labeled amino acids and peptides by Clostridium perfringens was measured in culture media containing acid or papain hydrolysates of C(14)-labeled Chlorella protein. Between 2 and 4 hr of growth, the rate of C(14) uptake from peptides was higher than from free amino acids. Peptides extracted from cells with hot ethyl alcohol contained six to nine times more C(14) after 4 hr of growth with C(14) labeled peptides than with C(14)-labeled amino acids. Incorporation of C(14) labeled glycine, serine, threonine, alanine, and proline into both cellular and exocellular protein was two to five times higher when these were supplied as components of dialyzable peptides rather than as free amino acids. PMID- 4285334 TI - Previously unrecognized virus from submaxillary glands of gnotobiotic and conventional rats. AB - Ashe, Warren K. (National Institute of Dental Research, Bethesda, Md.), Henry W. Scherp, and Robert J. Fitzgerald. Previously unrecognized virus from submaxillary glands of gnotobiotic and conventional rats. J. Bacteriol. 90:1719-1729. 1965.-A serially transmissible cytopathic agent was isolated from histologically normal submaxillary glands, but not from various other tissues or specimens, from 74 of 97 gnotobiotic and conventional rats. Triturates of the glands or subsequent culture supernatant fluids induced specific cytopathic effects (CPE) in monolayer cultures of primary rabbit kidney cells (14 passages), a line of human skin cells (8 passages), and HeLa cells (17 passages). Transfer of supernatant fluids containing infected cells enhanced transmissibility. Neutralization of the CPE was demonstrated with sera of gnotobiotic and conventional rats and with homologous rabbit antiserum. A cold hemagglutinin specific for rabbit erythrocytes is associated with, but separable from, the infectious particle. Cultures of the agent induced no discernible effect on inoculation by various routes into suckling, weanling, or adult conventional mice, rats, and hamsters. Weanling and adult rabbits were also unaffected. Cultures for bacteria in gland extracts and infected cell supernatant fluids were uniformly negative. Negative cultures on PPLO media and negative arginine deiminase tests indicated that this agent is not a Mycoplasma. The data indicate that it is a virus whose biological and physical properties distinguish it from the known cytomegaloviruses. Because it has been found so far only in rat submaxillary glands, this agent is designated provisionally as RSMG virus. PMID- 4285335 TI - Peptides for toxinogenesis of Clostridium perfringens type D. PMID- 4285336 TI - A sample holder for electron spin resonance studies on x-irradiated fibres. PMID- 4285337 TI - The role of radiation therapy in the treatment of chemodectomas of the glomus jugulare. PMID- 4285338 TI - Nasopharyngeal angiofibroma, an angiographic evaluation. PMID- 4285339 TI - [Chemotherapy and corticosteroids in pulmonary tuberculosis]. PMID- 4285340 TI - Contributions of electron microscopy to occupational health. PMID- 4285341 TI - Multiple respiratory virus infections in hospitalized children. PMID- 4285342 TI - Poliomyelitis in an isolated population: report of a type 1 epidemic in the Marshall Islands, 1963. PMID- 4285344 TI - Histological studies of the monkey neurovirulence of group B arboviruses. I. A semiquantitative grading scale. PMID- 4285343 TI - Some bactericidal and virucidal properties of iodine not affecting infectious RNA and DNA. PMID- 4285345 TI - Clinical reactions following bronchography. PMID- 4285346 TI - Mixed tumors of major salivary glands: prognostic role of capsular structure. PMID- 4285347 TI - [Preliminary report: determination of the pituitary ACTH reserve using metyrapone, based on the measurement of urinary levels of 11-desoxy-17, 21 dihydroxycorticosteroids (11-DOCS)]. PMID- 4285348 TI - Skeletal and denture patterns in children from Yuendumu, Central Australia, and Melbourne. PMID- 4285349 TI - The hypoglycaemic effect of mebanazine (Actomol) and its mechanism. PMID- 4285351 TI - [Contribution to a non-isotopic method of testosterone determination]. PMID- 4285350 TI - The estimation of the kallidins in blood and urine. PMID- 4285352 TI - Actinomycetes activity against foot and mouth disease virus determined by a new method. PMID- 4285353 TI - [The ultrastructure of the isolated rabbit auricle treated with angiotensin]. PMID- 4285354 TI - Biochemical changes in denervated skeletal muscle. 3. The effect of denervation atrophy on the concentration and 32P labelling of the individual phospholipids of the rat gastrocnemius. PMID- 4285355 TI - The stimulation of free radical formation in Arthrobacter sp. by manganous ions. PMID- 4285356 TI - "Fucidin" therapy in carcinoma of the breast. (Preliminary report). PMID- 4285358 TI - Quinhydrone as quantitative standard for electron spin resonance spectrometry of biological systems. PMID- 4285357 TI - [Apropos of the functional reserves of the adrenal cortex in children with thoracic forms of tuberculosis]. PMID- 4285359 TI - [On the X-band-ruby molecular amplifyer with an operational temperature of 90 degrees K for biophysical applications]. PMID- 4285360 TI - Preliminary clinical study of mithramycin (nsc-24559) in primary tumors of the central nervous system. PMID- 4285361 TI - The use of collagenase in investigating the synthetic balance of the intercellular materials. PMID- 4285362 TI - Quantitative assay of granaticin by the microbiological diffusion method. PMID- 4285363 TI - [Effect of some substances on the bone tissue of rats]. PMID- 4285364 TI - Bacteriuria during indwelling catheter drainage. Effect of constant bladder rinse. PMID- 4285365 TI - [Adenoviruses. A survey and a serological investigation among Norwegian soldiers]. PMID- 4285366 TI - [Results of polio vaccinations with the Salk vaccine in North-Rhine-Westphalia during 1957-1961]. PMID- 4285368 TI - Cytopathic effects and immunofluorescence produced by the J 121 strain of bovine Parainfluenza 3 virus in tissue culture. PMID- 4285367 TI - [Timing and localization of the synthesis of nucleic acids during the eclipse phase of the SV40 virus]. PMID- 4285370 TI - [Nursing care of patients with type B epidemic encephalitis]. PMID- 4285369 TI - A new adenovirus serotype of bovine origin. PMID- 4285371 TI - Histochemical studies of some oxidative enzymes in parenchymal cell damage of the liver of rats fed on 3'-methyl-4-dimethylaminoazobenzene. PMID- 4285372 TI - [Ultrastructural arguments in favor of the histogenetic oneness of astrocytomas, glioblastoma multiforme and oligodendrogliomas]. PMID- 4285373 TI - Investigations on interferon induced by statolon. PMID- 4285374 TI - The effect of arabinofuranosylcytosine on the growth cycle of simian virus 40. PMID- 4285375 TI - Attempts to detect an integrated polyoma genome by nucleic acid hybridization II. Complementarity between polyoma virus DNA and normal mouse synthetic RNA. PMID- 4285377 TI - Effect of lymphoid leukosis virus on the response of the chorioallantoic membrane to Rous sarcoma virus. PMID- 4285376 TI - A single-cell study of chemical inhibition of enterovirus multiplication. PMID- 4285378 TI - The inhibition by actinomycin D of poliovirus multiplication HEp 2 cells. PMID- 4285379 TI - Formation of tumor colonies in the lungs of rats injected with rat embryo cells immediately after infection of the cells with polyoma virus. PMID- 4285380 TI - Tumor production in the Japanese quail by the Schmidt-Ruppin strain of Rous sarcoma virus. PMID- 4285381 TI - The inactivation of simian virus 40 infectivity and antigen-inducing capacity by ultraviolet light. PMID- 4285382 TI - Immunochemical studies on some serological cross-reactions in the Klebsiella group. 10. Structure of the capsular polysaccharide of Klebsiella type 3 (C). PMID- 4285383 TI - Hepatoma associated with erythrocytosis. PMID- 4285384 TI - Basal cell nevus syndrome. Combined clinical staff conference at the National Institutes of Health. PMID- 4285385 TI - [Public health equipment of French expression in African countries: the Ivory Coast]. PMID- 4285386 TI - On the incorporation of tritium in yeast alcoholdehydrogenase from ethanol-T or NADH-T. PMID- 4285387 TI - Effect of cortisone on activation of lysosomal enzymes resulting from mengovirus infection of L-929 cells. PMID- 4285389 TI - Studies on the N-demethylation of morphine and other compounds. PMID- 4285388 TI - Tissue specificity of malate dehydrogenase isozymes. Kinetic discrimination by oxaloacetate and its mono- and difluoro analogues. PMID- 4285391 TI - Some biochemical effects of sporidesmin. PMID- 4285390 TI - Selective inhibition of nicotinamide adenine dinucleotide dependent oxidation by 2-methyl-3-o-tolyl-4-quinazolone. PMID- 4285392 TI - Glycoproteins as components of the lethal factors in cobra venom (Naja naja). PMID- 4285393 TI - Studies on biosynthetic enzymes. I. Mutant forms of histidinol dehydrogenase from Neurospora crassa. PMID- 4285394 TI - Total synthesis of the antibiotic polymyxin B-1. PMID- 4285395 TI - The stability of angiotensinamide in the presence of urea. PMID- 4285396 TI - Phosphoproteinphosphatase activity in sea urchin embryos. PMID- 4285397 TI - The reaction of rabbits to Rous sarcoma virus. PMID- 4285398 TI - [Persistent modification of mitochondria in adenovirus 12-induced hamster tumor cells]. PMID- 4285399 TI - [Usefulness of the angiotensin infusion test (test of Kaplan and Silah) for diagnosis of renovascular hypertension]. PMID- 4285400 TI - Respiratory virus infections of man and animals. Viruses associated with human respiratory infections. PMID- 4285401 TI - Respiratory virus infections in man and animals. Some bovine respiratory viruses. PMID- 4285402 TI - [Quartz content in dust in the grain elevator "Ewa" in Szczecin]. PMID- 4285403 TI - [Morphological characteristics of herpes simplex virus particles]. PMID- 4285404 TI - [Sensitivity of diploid cell strains and other cell cultures to rhinoviruses]. PMID- 4285405 TI - [ [Cultivation of smallpox viruses in developing chick embryos]. PMID- 4285406 TI - [Fractionation of Japanese encephalitis viruses with the use column chromatography on calcium phosphate]. PMID- 4285407 TI - [The age-factor in the distribution of para-influenza viruses]. PMID- 4285408 TI - [SV-40 virus infection of monkeys in North Vietnamese jungle]. PMID- 4285409 TI - [Metastases of nephroblastoma in children (Possibilities of treatment: surgery, radiotherapy, actinomycin D)]. PMID- 4285410 TI - Standardization of the fluorescent antibody technique for the detection of avian respiratory viruses. PMID- 4285411 TI - Studies on the RIF test for the detection of an avian leukosis virus. PMID- 4285412 TI - Avian lymphomatosis. IX. Mortality and serological response of chickens of various ages to graded doses of T strain. PMID- 4285413 TI - Fluorescent-microscopic investigation of cell cultures infected with Virus herpes simplex. PMID- 4285414 TI - In vitro antiviral activity of hydrazine sulfate. PMID- 4285415 TI - Adrenocortical activity and peripheral adrenergic responses in the cat. PMID- 4285416 TI - Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes. PMID- 4285417 TI - Hormone-secreting tumors of the adrenal cortex in children. PMID- 4285419 TI - The management of tumours in children. PMID- 4285418 TI - Study of viral antibodies by the paper-radioactive virus method. PMID- 4285420 TI - Relative target sizes for the inactivation of the transforming and reproductive abilities of polyoma virus. PMID- 4285421 TI - Radiation target size of the lytic and the transforming ability of polyoma virus. PMID- 4285422 TI - The nucleic acid of the Bryan strain of Rous sarcoma virus: purification of the virus and isolation of the nucleic acid. PMID- 4285424 TI - Angiographic diagnosis of malignant disease of the liver. PMID- 4285423 TI - Evidence that a phosphorylated intermediate in a brain transport adenosine triphosphatase is an acyl phosphate. PMID- 4285425 TI - Dermatitis as a complication of lymphangiography. PMID- 4285426 TI - [Problems and possibilities of exploration of the ultrastructure of the peripheral nervous system]. PMID- 4285427 TI - [Neurophysiological studies on sudoral secretion. Introduction to hidropharmacology]. PMID- 4285428 TI - [Glomus tumors of the stomach]. PMID- 4285429 TI - [Reactivity of the hypophyseal-adrenal system in neurotics]. PMID- 4285430 TI - The release of deep pain by nerve injury. PMID- 4285431 TI - Cell-free transmission of 20-methylcholanthrene-induced RF mouse leukemia, and electron microscopic demonstration of virus particles in the leukemic tissue. PMID- 4285432 TI - Etiology of upper-respiratory-tract illnesses among civilian adults. PMID- 4285434 TI - Genetic factors in breast cancer. PMID- 4285433 TI - Immunization by selective infection with type 4 adenovirus grown in human diploid tissue culture. II. specific protective effect against epidemic disease. PMID- 4285435 TI - The role of viruses in breast cancer causation. PMID- 4285436 TI - The meaning of biochemical differences between normal and cancer cells. PMID- 4285437 TI - Effects on central nervous system, peripheral nerve, myoneural junction, and muscle by carcinoma remote from such organs. PMID- 4285438 TI - Viruses as related to cancer. PMID- 4285439 TI - Remarks on oncogenic virus-cell relationships. PMID- 4285441 TI - [Amyloid neuropathy]. PMID- 4285440 TI - [Investigations on the occurrence of neutralizing antibodies against respiratory syncytial virus in the population]. PMID- 4285442 TI - The inhibitory effect of pyrophosphate on calcium oxalate precipitation and its relation to urolithiasis. PMID- 4285443 TI - Some remarks about the effect of glycerol on cells during freezing and thawing: electron-spin resonance investigations concerning this effect. PMID- 4285444 TI - Paramagnetic absorption of irradiated glycine. PMID- 4285445 TI - Comments on the factors controlling product stereospecificity in the reduction of carbonyl compounds with alcohol dehydrogenase and diphosphopyridine nucleotide. PMID- 4285446 TI - The isolation and selected properties of blood monocytes. AB - A technique is described for the quantitative recovery of monocytes from horse blood by means of flotation on dense albumin solutions. Monocytes are concentrated in a surface pellicle along with a few lymphocytes which are then removed when the monocytes adhere to a glass surface. The in vitro cultivation of homogeneous populations of monocytes results in an increase in (a) cell size, (b) number of mitochondria, and (c) phase-dense granules of the centrosphere. The phase-dense granules are osmiophilic and acid phosphatase positive. Quantitative biochemical analysis during cultivation have revealed increased levels of cytochrome oxidase, acid phosphatase, arylsulfatase, and BPN hydrolase. In addition, glucose utilization and lactic acid production are stimulated under the same conditions. The uptake of both bacteria and colloidal gold is stimulated during in vitro cultivation. The phagocytic activity of cultured monocytes may be enhanced by a purified bacterial lipopolysaccharide. These data are consistant with the in vitro maturation of monocytes to macrophages, a cell with greater metabolic and functional potentional. PMID- 4285447 TI - The role of methionine deficiency in poliovirus replication in tissue cultures. AB - The role of methionine in poliovirus infection in HeLa and monkey kidney cells was investigated by using the methionine analogue l-ethionine. In the presence of 2.0 x 10(-3) and 4.0 x 10(-3) moles ethionine, the growth of HeLa and monkey kidney cells was significantly inhibited. Under the same experimental conditions, ethionine had no significant effect on the biosynthesis of two strains of poliovirus (Mahoney and Lansing) in HeLa cells, whereas in primary monkey kidney cells, it markedly inhibited the biosynthesis of the Lansing strain of poliovirus. HeLa cells partly depleted of their intracellular amino acids did not change the rate of viral biosynthesis. The inhibitory effect of ethionine on cell growth and viral biosynthesis was reversed by addition of an excess of l methionine. PMID- 4285448 TI - Extracellular products of blue-green algae. PMID- 4285449 TI - The treatment of multiple sclerosis with ACTH. PMID- 4285450 TI - Serologic and virus-isolation studies of patients with varicella or herpes-zoster infection. PMID- 4285451 TI - [Pregnancy and non-specific hemorrhagic proctocolitis (hemorrhagic proctitis and ulcerative colitis)]. PMID- 4285452 TI - Antiviral activity of herbs on Columbia SK in mice, and LSM, vaccinia and adeno type 12 viruses in vitro. PMID- 4285453 TI - Complement fixation: a modified procedure designed to eliminate anticomplementary and procomplementary effects. PMID- 4285454 TI - Inhibition of renin secretion by angiotensin. II. PMID- 4285455 TI - Effect of dietary orotic acid on liver glycogen. PMID- 4285456 TI - Ependymomas produced in Syrian hamsters by adenovirus 7, strain E46 ("hybrid" of adenovirus 7 and SV40). PMID- 4285457 TI - Lactic dehydrogenase isozymes in rat tissues, tumors, and precancerous livers. PMID- 4285458 TI - New method of detection of certain bacterial oxidoreductases and transaminases by the indicator reaction on agar. PMID- 4285459 TI - Studies of avian sarcoma and erythroblastosis (strain 13). IV. pH stability of the virus at 2 degrees Ca. PMID- 4285460 TI - The connective tissues of peripheral nerves. PMID- 4285461 TI - The recovery of smallpox virus from patients and their environment in a smallpox hospital. AB - Attempts had been made in 1961 to recover smallpox virus by air sampling in smallpox wards and close to the mouths of smallpox patients, but these had been largely unsuccessful, possibly owing to the air sampling method used. Further attempts were therefore made in 1963, with a fluid impinger for air sampling and with Petri dishes placed below the orifice of the impinger to collect large droplets or particulate matter that the impinger might miss.Air samples from near the patients' mouths yielded little virus, this being more readily recovered from the settling-plates. Patients' bedclothes sampled with the impinger yielded rather more virus, but again even more was obtained from the Petri dishes.The results suggest that contamination of the air in the vicinity of smallpox patients is due to relatively large particles of infected dust from the patients' bedclothes rather than from fine droplets or droplet nuclei coming from the upper respiratory tract. Secretions from the mouth and upper respiratory tract appear to be responsible for the early contamination of pillows and bedclothes. PMID- 4285462 TI - Injuries to nerves and tendons in the hand and forearm: technique of repair. PMID- 4285463 TI - [Studies on the metabolism of 17-alpha-hydroxy-19-norprogesterone caproate by humans in vivo and of 17-alpha-hydroxy-19-norprogesterone by rats in vitro]. PMID- 4285464 TI - Bacterial nucleate and phosphorus partition. PMID- 4285465 TI - Antibodies for Rous sarcoma virus in fowl, animal, and human populations of East Africa. I. Antibodies in domestic chickens and wildfowl. PMID- 4285466 TI - Studies on the carcinogenic activity of protein-denaturing agents: hepatocarcinogenicity of dioxane. PMID- 4285467 TI - [Histochemical findings and significance of phosphatase activity in cerebral tumors]. PMID- 4285469 TI - [Surgical iatrogenic lesions of peripheral nerves]. PMID- 4285468 TI - [Our experiences with surgical treatment of injured peripheral nerves]. PMID- 4285470 TI - Deoxyribonucleic acid synthesis in Escherichia coli infected with some deoxyribonucleic acid polymerase-less mutants of bacteriophage T4. PMID- 4285471 TI - Incomplete growth of simian virus 40 in African green monkey kidney culture induced by serial undiluted passages. PMID- 4285472 TI - A comparison of the replication cycles of simian virus 40 in human diploid and African green monkey kidney cells. PMID- 4285473 TI - Studies on the thymidine kinase activity of mouse embryo cells infected with polyoma virus. PMID- 4285474 TI - SV40-adenovirus "hybrids": presence of two genotypes and the requirement of their complementation for viral replication. PMID- 4285475 TI - [On the effect of some virus strains on the lipid metabolism]. PMID- 4285476 TI - The fate of the alphah atom of L-lactate in perfused rat liver. PMID- 4285477 TI - The lactic dehydrogenases of E. coli. PMID- 4285479 TI - L(+) lactic acid and the steady state of cellular red/ox-systems. PMID- 4285478 TI - Propanediol metabolism and its relation to lactic acid metabolism. PMID- 4285480 TI - [So-called mixed salivary tumors of the larynx]. PMID- 4285481 TI - [False mixed tumor of the parotid gland. (Discussion of the diagnosis and prognosis)]. PMID- 4285482 TI - [2 cases of tumors of glomic nature appearing after petro-mastoid evidement]. PMID- 4285483 TI - [First findings on validity of Papanicolaou's cytologic examination in some types of synovial lesions. Synoviocytogram]. PMID- 4285484 TI - Cytochrome 559 in the microsomes of the adrenal medulla. PMID- 4285486 TI - A novel plate assay method for amoebicides. PMID- 4285485 TI - [On the action of angiotensin II on the adrenal cortex during chemical adrenostasis with SU 4885 (metopirone)]. PMID- 4285487 TI - [Periadenitis mucosa necrotica recurrens]. PMID- 4285488 TI - Contamination of egg-adapted canine distemper vaccine by avian leukosis virus. PMID- 4285489 TI - Crystal-induced myocarditis and pericarditis. PMID- 4285490 TI - Porosyringoma. Report of a case. PMID- 4285491 TI - Electron microscopy of tissue cultures infected with porcine polioencephalomyelitis virus. PMID- 4285492 TI - The fate of serial heterologously transplanted glioblastoma multiforme in the eye of the guinea pig. PMID- 4285493 TI - Brain as target organ in Clostridium perfringens exotoxin toxicity. PMID- 4285494 TI - Studies on menadione reductase of bakers' yeast. II. Inhibition of the enzyme activity by NAD and stimulation of that by p-chloromercuribenzoate. PMID- 4285495 TI - Effects of urea on the activity and structure of yeast alcohol dehydrogenase. PMID- 4285496 TI - Evaluation of indices of juxtaglomerular cells and zona glomerulosa in human and experimental cirrhosis. PMID- 4285497 TI - The effect of angiotensinii on the "clearance" of radioiodine from the skin in hypertension. PMID- 4285498 TI - The electrophoretic separation of lactate dehydrogenase isoenzymes and their evaluation in clinical medicine. PMID- 4285499 TI - Protein abnormalities in neuromuscular diseases. I. PMID- 4285500 TI - [Metabolic changes of the brain in non-fatal potassium cyanide poisoning and its modification by cyanide antagonists]. PMID- 4285501 TI - Intraperitoneal hemorrhagic rupture of liver. PMID- 4285502 TI - [Contribution to the knowledge of angiofibromas of the rhinopharynx]. PMID- 4285503 TI - Parainfluenza 2 virus: increase in hemagglutinin titer on treatment with Tween-80 and ether. PMID- 4285504 TI - An orally active hypocholesteremic steroid with reduced uterotrophic effect. PMID- 4285505 TI - Peripheral arterial and renal venous angiotensin concentration. PMID- 4285506 TI - Reversible inhibition of DNA virus replication with mithramycin. PMID- 4285507 TI - Antiviral activity of ammonium picrate in mice. PMID- 4285508 TI - Effect of crude and purified interferons on the gowth of uninfected cells in culture. PMID- 4285509 TI - Interferon and uninfected cells. PMID- 4285510 TI - Effects of hypophysectomy on lipolytic response of adipose tissue to pituitary hormones. PMID- 4285511 TI - Purification of hypothalamic corticotrophin-releasing factor (CRF) of ovine origin. PMID- 4285512 TI - [Contribution to the study of pathology of embryonal residues of the female genital apparatus]. PMID- 4285513 TI - [Study on the influence of cytotoxic and non-cytotoxic substances in the genesis of pulmonary fibrosis]. PMID- 4285514 TI - The influence of adrenocorticotropic hormone and prednisolone upon marrow and circulating leukocytes in the dog. PMID- 4285515 TI - A quantitative study of the infectious bovine rhinotracheitis neutralization test. PMID- 4285516 TI - Electron microscopy of cytomegalic inclusion disease of swine (inclusion body rhinitis). PMID- 4285517 TI - Glomus jugularis tumors. PMID- 4285518 TI - Amoebiasis in Saskatchewan. PMID- 4285519 TI - Glomus jugulare tumors. PMID- 4285520 TI - Antiamebic studies on 5-chloro-793-diethylaminopropyl-aminomethyl)-8-quinolinol in vitro and in experimentally infected animals. PMID- 4285521 TI - [Study of tumors induced in hamsters by the bovine papillomatosis virus]. PMID- 4285522 TI - Haemagglutination-inhibiting antibodies to adenovirus types 8, 9 and 10 in paired sera of patients with epidemic keratoconjunctivitis. PMID- 4285523 TI - [Investigation of the change in catalase activity of fucidin-resistant Staphyloccus aureus cultures]. PMID- 4285524 TI - Multiple sclerosis in vestfold county. PMID- 4285525 TI - The effect of angiotensin on renal circulation. PMID- 4285526 TI - Intratypic serodifferentiation of oral poliovaccine progeny. PMID- 4285527 TI - Path of carbon and assimilatory power in chemosynthetic bacteria. I. Nitrobacter agilis. PMID- 4285528 TI - The effect of ethanol metabolism on levels on oxidized and reduced nicotinamide adenine dinucleotide in liver, kidney, and heart. PMID- 4285529 TI - Changes in fungi with age. II. Respiration and respiratory enzymes of Rhizoctonia solani and Sclerotium bataticola. AB - Van Etten, James L. (University of Illinois, Urbana), H. Peter Molitoris, and David Gottlieb. Changes in fungi with age. II. Respiration and respiratory enzymes of Rhizoctonia solani and Sclerotium bataticola. J. Bacteriol. 91:169 175. 1966.-The rate of respiration of Rhizoctonia solani and Sclerotium bataticola decreased with age. This decrease in respiratory rate might be produced by a decrease in the specific activity of one or more enzymes involved in carbohydrate metabolism. Specific activities in cell-free extracts were measured for most of the enzymes in the hexose monophosphate shunt, Embden Meyerhof-Parnas pathway, tricarboxylic acid cycle, and terminal electron transport system. In addition, glucose oxidase, isocitritase, and malic enzyme were measured. In R. solani, increases in activity with age occurred for hexokinase, alpha-glycerolphosphate dehydrogenase, malic dehydrogenase, and cytochrome oxidase. Decreases occurred for phosphohexokinase, aconitase, nicotinamide adenine dinucleotide-specific isocitric dehydrogenase, reduced nicotinamide adenine dinucleotide oxidase, and at least one of the enzymes between 3-phosphoglycerate and pyruvate. In S. bataticola, increases in activity with age were observed for phosphohexokinase, pyruvic dehydrogenase, fumarase, malic dehydrogenase, and malic enzyme, whereas none of the enzymes decreased. The specific activities of the remaining enzymes did not change with age in either fungus. PMID- 4285530 TI - Inhibition of Mengo virus by interferon. AB - Gauntt, Charles J. (The University of Texas, Austin), and Royce Z. Lockart, Jr. Inhibition of Mengo virus by interferon. J. Bacteriol. 91:176-182. 1966.-The inhibition of Mengo virus replication in L cells resulting from interferon was studied quantitatively. Interferon was titrated on L cells with Western equine encephalomyelitis (WEE) virus as the challenge virus. One protective unit (PU) of interferon is the least amount of interferon which prevents cytopathic effects when a large multiplicity of WEE virus is added subsequent to overnight incubation with interferon. Ten PU of interferon reduced the yields of Mengo virus by about 90%. Larger doses of interferon, up to 220 PU, caused no further reduction in the amount of virus produced. Plaque formation by Mengo virus was also reduced in number by about 85 to 90%, but could not be further reduced. The plaques which formed on interferon-treated cells were reduced in size. We were unable to obtain a virus population with increased resistance to interferon action by use of five successive growth cycles in interferon-treated cultures. Analysis of the cell population for the proportion of cells able to act as infectious centers revealed that incubation of cells with 10 PU of interferon decreased the proportion of virus-yielding cells by 80%. The yield of virus per virus-producing cell was decreased by 40 to 60%. Despite the reduction in yields, plaques, and infectious centers resulting from interferon, all doses of interferon failed to prevent the complete destruction of the cells. Experiments with puromycin indicated that the cytopathic effects observed in L cells infected with Mengo virus required that a virus-directed protein be synthesized between 4 and 5 hr postinfection. The evidence suggested, therefore, that the Mengo virus genome was able to code for new protein synthesis in the absence of the production of infectious virus. PMID- 4285531 TI - Specific cell-surface alteration by enteroviruses as reflected by viral attachment interference. AB - Crowell, Richard L. (Hahnemann Medical College, Philadelphia, Pa.). Specific cell surface alteration by enteroviruses as reflected by viral-attachment interference. J. Bacteriol. 91:198-204. 1966.-Exposure of HeLa cells to high levels of coxsackievirus B3 produced cells which were refractory to attachment of coxsackievirus B1, whereas poliovirus T2 attached normally. Under similar conditions, poliovirus T2 was found to interfere with the attachment of poliovirus T1 to HeLa cells without affecting the attachment rate of coxsackievirus B3. The data confirm earlier findings that the receptor sites on HeLa cells, which bind members of group B coxsackieviruses, are distinct from those for polioviruses. Quantitatively, coxsackieviruses B1 and B3 were found to be mutually exclusive in the attachment interference assay to suggest that they compete for the same receptors on the HeLa cell surface. The finding that input multiplicities of B3 virus which exceeded 500 saturated the homologous viral receptors of HeLa cells was unexpected, but was consistent with the results of interference assays. Excessive amounts of input virus did not, however, inhibit eclipse of homologous cell-associated virus. Attachment interference between enteroviruses occurred even though the interfering virus was eclipsed prior to addition of challenge virus. The finding that enterovirus attachment interference was reversible with acid pH suggested that attachment and eclipse of enterovirus does not result in a permanent alteration of the cell membrane and that these events occur at the cell surface. PMID- 4285532 TI - Interactions of human cytomegalovirus with human fibroblasts. AB - Vonka, Vladimir (Baylor University College of Medicine, Houston, Tex.), and Matilda Benyesh-Melnick. Interactions of human cytomegalovirus with human fibroblasts. J. Bacteriol. 91:213-220. 1966.-Virus attachment of human cytomegalovirus to human embryo lung fibroblasts was found to be temperature independent, from 4 to 37 C. Prolonged incubation at 4 C, however, resulted in inactivation of a high proportion of attached virus. Virus penetration seemed to be temperature-dependent, occurring at 37 C but not at 4 C. Detailed studies of the growth curve of the virus were made. Cell-associated virus preceded the appearance of virus in the fluid phase by 2 to 5 days. Complement-fixing antigen could be detected, but only when the cytopathic effect was advanced, and it was demonstrable only in the cell-associated fraction. Under methyl cellulose, decreasing the bicarbonate concentration in the overlay from 0.225 to 0.15% resulted in marked increase in plating efficiency with all strains tested. However, varying the concentration of bicarbonate from 0.3 to 0.15% in fluid medium did not influence the growth of virus. PMID- 4285533 TI - Thermoinactivation of human cytomegalovirus. AB - Vonka, Vladimir (Baylor University College of Medicine, Houston, Tex.), and Matilda Benyesh-Melnick. Thermoinactivation of human cytomegalovirus. J. Bacteriol. 91:221-226. 1966.-The inactivation at 4 and 37 C of several strains of human cytomegalovirus was studied. The preliminary findings that freshly harvested cytomegalovirus was inactivated more rapidly at 4 C than at higher temperatures was confirmed. Intracellular virus still within infected cells was found to be more stable at 4 C than virus released by sonic treatment just before incubation at 4 C. The composition of the diluent played an important role. In tris(hydroxymethyl)-aminomethane buffer, virus was unstable at both 4 and 37 C, with the rate of inactivation faster at 4 than at 37 C. Similar results were obtained when bicarbonate-phosphate buffer or Eagle's medium when bicarbonate was used as virus diluent. Calf serum stabilized the virus at 37 C, but not at 4 C. The deletion of bicarbonate from Eagle's medium had a stabilizing effect at both temperatures. An even greater stabilizing effect at both 4 and 37 C was obtained when distilled water was used as virus diluent. Inactivation rates varied from one strain to the next at 4 C but not at 37 C. Differences were found also with virus progeny derived from a single strain, but harvested at different stages during virus multiplication. Virus harvested early was more labile at 4 than at 37 C, whereas the late virus was more labile at the higher temperature. Intracellular and extracellular virus preparations were inactivated at the same rates at either 4 or 37 C. PMID- 4285534 TI - Antiviral action of mouse interferon in heterologous cells. AB - Buckler, Charles E. (National Institute of Allergy and Infectious Diseases, Bethesda, Md.), and Samuel Baron. Antiviral action of mouse interferon in heterologous cells. J. Bacteriol. 91:231-235. 1966.-The antiviral action of mouse interferon in cell cultures of mouse, hamster, rat, chicken, and monkey origin was investigated. Using a vesicular stomatitis virus (VSV) plaque reduction test, we found that mouse serum interferon, assayed on closely related rat or hamster cells, exerted 5% of its homologous antiviral activity. This activity was characterized as interferon by its temperature of inactivation, trypsin sensitivity, nonsedimentability, stability at pH 2, lack of inactivation by antibody to virus, and inability to be washed off cells. In the more distantly related chicken and monkey cells, mouse interferon had less than 0.1% of its homologous activity. Conflicting reports of heterologous activity of chicken and mouse interferon preparations may result in part from the observed action of noninterferon inhibitors of vaccinia virus. These inhibitors, like interferon, are stable at pH 2. They are present in mouse serum, mouse lung extracts, and allantoic fluid, and they prevent the development of vaccinia plaques when allowed to remain in contact with cells during virus growth. Unlike interferon the inhibitors are removed by adequate washing of cells prior to virus challenge, and they are not active in the VSV assay system. These findings reemphasize the need for thorough characterization of interferon preparations. PMID- 4285535 TI - Replication in simian cells of defective viruses in an SV40-adenovirus "hybrid" population. AB - Butel, Janet S. (Baylor University College of Medicine, Houston, Tex.), and Fred Rapp. Replication in simian cells of defective viruses in an SV40-adenovirus "hybrid" population. J. Bacteriol. 91:278-284. 1966.-An SV40-adenovirus type 7 "hybrid" virus population, previously shown to contain two viruses capable of complementation in green monkey kidney (GMK) cells, has a growth cycle in GMK cells similar to that of adenovirus type 7 in the presence of SV40. Extending previous preliminary results, the addition of adenovirus types 2, 7, or 12 to monolayers of GMK cells enhanced plaque formation by the SV40-adenovirus hybrid by as much as 200-fold. The terminal enhanced plaques, initiated by the hybrid in the presence of helper adenovirus, were found to contain progeny which could induce the synthesis of SV40 tumor antigen but which were coated with the protein of the helper adenovirus, type 2, 7, or 12, respectively. The particle carrying the SV40 tumor antigen determinant, named PARA, is defective in that it cannot direct the synthesis of capsid protein; information for the coat for PARA is supplied by the adenovirus. One-step growth curves of the hybrid virus population in monkey cells revealed that synthesis of both types of particles, adenovirus and PARA, proceeds at a similar rate, with a latent period of 16 to 20 hr being followed by an exponential increase in titer during the following 20 hr. Maximal titers for both particles were obtained 48 hr after inoculation of the cultures. Neither the PARA nor the adenovirus component replicated in GMK cells in the absence of the other. PMID- 4285536 TI - Bacteriophage-induced functions in Escherichia coli K (lambda) infected with rII mutants of bacteriophage T4. AB - Rutberg, Blanka (Karolinska Institutet, Stockholm, Sweden), and Lars Rutberg. Bacteriophage-induced functions in Escherichia coli K(lambda) infected with rII mutants of bacteriophage T4. J. Bacteriol. 91:76-80. 1966.-When Escherichia coli K(lambda) was infected with rII mutants of phage T4, deoxycytidine triphosphatase, one of the phage-induced early enzymes, was produced at initially the same rate as in r(+)-infected cells. Deoxyribonuclease activity was one-third to one-half of that of r(+)-infected cells. This lower deoxyribonuclease activity was observed also in other hosts or when infection was made with rI or rIII mutants. Presence of chloramphenicol did not allow a continued synthesis of phage deoxyribonucleic acid in rII-infected K(lambda). No phage lysozyme was detected nor was any antiphage serum-blocking antigen found in rII-infected K(lambda). It is suggested that the rII gene is of significance for the expression of phage induced late functions in the host K(lambda). PMID- 4285537 TI - Purification and properties of phosphodiesterase from bovine pancreas. PMID- 4285538 TI - Notes on the role of sulfhydryl and imidazole groups in myosin nucleoside triphosphatase and contraction of glycerinated muscle fibers. PMID- 4285539 TI - Antibody for collagenase from Clostridium histolyticum. PMID- 4285540 TI - The footprints of tumor viruses. PMID- 4285541 TI - [The gastric mucosa in aged patients. Biologic and anatomic study]. PMID- 4285542 TI - [The functional treatment of fractures of the dorso-lumbar spine]. PMID- 4285543 TI - [Arterial auscultation and phonangiography in diseases of the arteries. Their diagnostic value]. PMID- 4285544 TI - [Intestinal hemorrhage caused by rupture of a varix of the colon. Segmental colic resection. Recovery]. PMID- 4285545 TI - [Complete obstruction of the inferior vena cava. Exploration by cavography. (Apropos of a case of cancer of the kidney)]. PMID- 4285546 TI - [Considerations on the auricular activity of complete arrhythmia]. PMID- 4285547 TI - [Anatomo-clinical aspects of Balkan endemic nephropathy]. PMID- 4285548 TI - [Cytotoxic effect of poxviruses]. PMID- 4285549 TI - Effect of diencephalic and midbrain stimulation on ACTH levels in unrestrained cats. PMID- 4285550 TI - [Islet cell tumors of the pancreas. Diagnostic and therapeutic problems]. PMID- 4285551 TI - Genetic and possible biochemical mechanisms in viral carcinogenesis. PMID- 4285552 TI - The effect of corticosteroids and altered adrenal function on liver regeneration following chemical necrosis and partial hepatectomy. PMID- 4285553 TI - Plasma enzymes in tumor-bearing rats. PMID- 4285554 TI - Effects of 6-diazo-5-oxol-norleucine and other tumor inhibitors on the biosynthesis of nicotinamide adenine dinucleotide in mice. PMID- 4285555 TI - Neoplasms following irradiation of the head. PMID- 4285556 TI - [Electron spin resonance for research on the kinetics and mechanism of Cu2+ catalyzed reactions]. PMID- 4285557 TI - Decontamination of pleuropneumonia-like organism (PPLO) infected tissue cultures. PMID- 4285559 TI - Role of interferon during viremia. II. Protective action of circulating interferon. PMID- 4285558 TI - Role of interferon during viremia. I. Production of circulating interferon. PMID- 4285560 TI - Viruria in herpes simplex infection of mice. PMID- 4285561 TI - The control of pituitary corticotrophic function. PMID- 4285562 TI - Hemorrhage in normal man. The effects of angiotensin. PMID- 4285563 TI - Breast carcinoma in children. PMID- 4285564 TI - [The use of labeled products in the analysis of bilio-lymphatic permeation and bilio-blood permeation]. PMID- 4285565 TI - [A case of pituitary dwarfism treated with ACTH]. PMID- 4285567 TI - Adrenocortical response to high dosage ACTH therapy in patients with multiple sclerosis. PMID- 4285566 TI - Estimation of plasma renin and renin-substrate in various diseases in man. PMID- 4285568 TI - Adsorption of attenuated and neurovirulent strains of poliovirus to central nervous system tissues. PMID- 4285569 TI - Multifocal pseudohypertrophic neuropathy. PMID- 4285570 TI - Cellular and antiviral effects of halogenated deoxyribonucleosides. PMID- 4285571 TI - Inhibition by halogenated deoxyribonucleosides of the production of tumors by a polyoma virus. PMID- 4285572 TI - Antiviral substances. Nucleosides. Discussion. PMID- 4285573 TI - Indirect inhibition of protein synthesis. PMID- 4285574 TI - Experiences in developing potential antiviral compounds. PMID- 4285575 TI - Direct inhibition of protein synthesis and its effect upon the growth of RNA viruses. PMID- 4285576 TI - Further studies on the effect of p-fluorophenylalanine and puromycin on polio virus replication. PMID- 4285577 TI - The use of antiviral compounds in analyzing the sequential steps in the replication of SV40 papovavirus. PMID- 4285578 TI - Mechanism of cell damage in polio virus infection. PMID- 4285579 TI - Agents useful in the study of mechanisms of viral replication. Discussion. PMID- 4285580 TI - Problems of in vitro and in vivo testing of antiviral substances. PMID- 4285581 TI - Tumorigenic virus and cell responses to biologically active compounds. II. Pharmacologic specificity in cell-virus relationships. PMID- 4285582 TI - Development of resistance to antiviral drugs. PMID- 4285583 TI - In vivo and in vitro inhibition of hepatitis viruses by streptothricin. PMID- 4285584 TI - Antiviral activity of paolins from clams. PMID- 4285585 TI - The effect of polyanions and polycations on Mengo virus--l cell interaction. PMID- 4285586 TI - The characteristic and relationships of virus resistance and dependence to guanidine and other compounds. PMID- 4285587 TI - Studies on the antiviral activity of amantadine hydrochloride. PMID- 4285588 TI - "Cyclopin". PMID- 4285589 TI - Virus inhibitory activity of biguanides and related compounds. PMID- 4285590 TI - Antiviral activity of some pteridines in animals. PMID- 4285591 TI - Antiviral activities of extracts of the lemon balm plant. PMID- 4285592 TI - Observations on antiviral screening. PMID- 4285593 TI - Searching for antiviral materials from microbial fermentations. PMID- 4285594 TI - Detection and evaluation of potential antiviral drugs. Discussion. PMID- 4285595 TI - The excretion of steroids by pre-pubertal children during growth. PMID- 4285596 TI - DNA lesions induced in nuclei and nucleoli of monkey kidney cells in tissue culture by simian vacuolating virus (SV40). PMID- 4285597 TI - Chromatographic fractionation of antibiotic 136 and characterization of its components. PMID- 4285598 TI - The semiquantitative determination of total and free silica by paper chromatography. PMID- 4285600 TI - [On neuro-vascular compression syndrome of upper extremities]. PMID- 4285599 TI - [Practical value of electrodiagnosis for the clinician]. PMID- 4285601 TI - On feline rhinotracheitis. PMID- 4285602 TI - Studies on the pathogenesis of gastroenteritis in swine. Preliminary report. PMID- 4285603 TI - Epinephrine and insulin effects. II. ACTH and cortisol. PMID- 4285604 TI - Corticotrophin and corticosteroids in the management of acute and chronic heart block. PMID- 4285605 TI - [Pituitary adrenocortical hypofunction in children following prednisone treatment]. PMID- 4285606 TI - Mitochondrial electron transport: effect of age on sensitivity to inhibitors. PMID- 4285608 TI - [Radiologic signs in chromosome aberrations]. PMID- 4285607 TI - The effect of radio-opaque substances on the ciliated epithelium of the trachea of rabbits. PMID- 4285610 TI - [Trial of the hypnotic RO 4-5360 in a geriatric environment by the "double-blind" method]. PMID- 4285609 TI - [Blood sugar disagreement in the double-determination oral hyperglycemia test]. PMID- 4285611 TI - [Thoughts on nonspherocytic chronic congenital hemolytic anemia: apropos of a case]. PMID- 4285612 TI - [The blood albumin, a prognostic element in ulcerations]. PMID- 4285613 TI - [The place of the thioamides in the treatment of pulmonary tuberculosis. (Role of TH 1321)]. PMID- 4285614 TI - [Cytodiagnosis in malignant tumors of the brain]. PMID- 4285615 TI - [Cerebral softening during the development of ruptured intracranial aneurysms]. PMID- 4285616 TI - [Clinical and psychological study of a "tranquilizing" or "myo-resolutive" treatment in the postoperative period of disk hernias]. PMID- 4285617 TI - [Migraine: current status of the question]. PMID- 4285618 TI - [Congenital muscular torticollis associated with dental and cardiac abnormalities]. PMID- 4285619 TI - [The colibacillus-lactobacillus combination in the treatment of diarrhea in adults, children and infants]. PMID- 4285620 TI - [Application of certain pharmacodynamic agents to cardiac auscultation]. PMID- 4285621 TI - [Cortisone and microcirculation]. PMID- 4285622 TI - [Apropos of a clinical experimentation with an aerosol bronchial mucous liquifier: N-acetyll-cysteine]. PMID- 4285624 TI - Studies of conformational changes in glyceraldehyde-3-phosphate dehydrogenase accompanying its catalytic action. PMID- 4285623 TI - [Myxedematous ascites]. PMID- 4285625 TI - Inhibition of the methylation of nicotinamide by chlorpromazine. PMID- 4285626 TI - Experimental infectious canine hepatitis. I. The pathology of the disease in guinea-pigs. PMID- 4285627 TI - Electron transfer within and between haemoprotein molecules. PMID- 4285628 TI - [Identification, by in vitro complementation and purification, of a peptide fraction of Escherichia coli beta-galactosidase]. PMID- 4285629 TI - An animal virus with DNA of high guanine + cytosine content which codes for S RNA. PMID- 4285630 TI - An unusual location of guineaworm infestation. Report of a case. PMID- 4285631 TI - Simian virus 40: replication in the presence of specific antiserum and adenovirus 4. AB - Twelve consecuttive passages of simian virus 40, made in the presence of adenovirus 4 and antiserum to simian virus 40, indicated that simian virus 40 would multiply almost indefinitely under these conditions. The adenovirus and the simian virus had previously replicated together in the absence of antiserum. These data support the conclusion that the SV-40 genome is incorporated within the protein coats of adenovirus 4. PMID- 4285632 TI - Serologic survey of equine rhinopneumonitis virus infection among horses in various countries. PMID- 4285634 TI - [Investigations on the genetic stability of the plaque picture of herpes simplex virus in cell cultures]. PMID- 4285633 TI - [Investigations on the relationships between biological activity and particle type in herpes simplex virus]. PMID- 4285635 TI - Properties of a new type 3 attenuated poliovirus. V. Neurovirulence tests in monkeys after a passage through the human alimentary tract. PMID- 4285637 TI - [Clinical and serologic responses of calves to the inoculation by respiratory route of a para-influenza 3 myxovirus]. PMID- 4285636 TI - Secondary antibody response of guinea pigs to parainfluenza and mumps viruses. PMID- 4285638 TI - Phosphatases of Mycobacterium 607. PMID- 4285639 TI - Influence of adrenal steroids on self-stimulation rates in rats. PMID- 4285640 TI - Experimental infection of calves with a bovine adenovirus. PMID- 4285641 TI - Renal vascular responses to drugs in experimental nephrosis in rats. PMID- 4285642 TI - Effect of actinomycin D and halogenated deoxyuridines on the replication of simian virus 5. PMID- 4285643 TI - Thermal separation of the synthesis of papovavirus SV40 tumor and virus antigens. PMID- 4285644 TI - Adrenal cortical function in experimental alcoholism in dogs. PMID- 4285645 TI - Sensitivity of strain R avian erythroblastosis virus to ether and chloroform. PMID- 4285646 TI - Blood pressure in female and male rats following ventromedial hypothalamic lesions placed at four different ages. PMID- 4285647 TI - Deoxyribonuclease I and II activities in liver and spleen of mice experimentally infected by mouse hepatitis virus. PMID- 4285648 TI - Characteristics of the growth cycles of four simian enteroviruses (SV2, SV6, SV42, SV49). PMID- 4285649 TI - [Studies on variola viruses in tissue culture]. PMID- 4285650 TI - [Virologic and serologic studies on adenoviruses in Warsaw in 1963-1964]. PMID- 4285651 TI - [Comparative studies on the sensitivity of the S-44 human diploid cell strain and primary monkey kidney cells to some viruses and its relation to the composition of culture media]. PMID- 4285652 TI - [An epidemic with E. coli O 78: B 80 in premature infants without dyspeptic symptoms]. PMID- 4285653 TI - Relationship between the ultrastructure and cortical activity of the embryonic adrenal gland in the chicken. PMID- 4285654 TI - [Studies on the metabolism of 17alpha-hydrexy-19-norprogesterone caproate by humans in vivo and of 17alpha-hydroxy-19norprogesterone by rats in vitro]. PMID- 4285655 TI - [Apropos of the glomus jugulare]. PMID- 4285656 TI - Microcirculatory approach to vasopressor therapy in intestinal ischemic (SMA) shock. PMID- 4285657 TI - Prolonged survival with islet cell carcinoma producing obstructive jaundice. PMID- 4285660 TI - Metabolism of pipecolic acid in a Pseudomonas species. 3. L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase. PMID- 4285658 TI - The effect of structure-disrupting ions on the activity of myosin and other enzymes. PMID- 4285659 TI - Studies on the identification and origin of ethanol in mammalian tissues. PMID- 4285661 TI - The synthesis of teichoic acids. V. Polyglucosylglycerol phosphate and polygalactosylglycerol phosphate. PMID- 4285662 TI - [Essay on diagnostic interpretation of the sulfobromophthalein test. IV. Personal method of expressing the sulfobromophthalein test and general results]. PMID- 4285663 TI - [Imported amebiasis. Apropos of 500 cases]. PMID- 4285664 TI - [Biotypological considerations concerning a student population]. PMID- 4285665 TI - [Cortisone-induced osseus rarefactions in asthmatic patients]. PMID- 4285666 TI - [Apropos of the myelomatous kidney]. PMID- 4285667 TI - [Preoperative care in podology]. PMID- 4285668 TI - [Therapeutic study of a new anxiolytic antidepressant (Noveril, L.W. 1927) in a group of 76 patients presenting a depression syndrome]. PMID- 4285669 TI - The effect of conjugated estrogens and estriol succinate on fibrinolysis: a clinical correlation in patients with uterine bleeding. PMID- 4285670 TI - [Bacteria quantity and fecal indicators in the water of Lake Constance]. PMID- 4285671 TI - [Results of virological investigations of sewage]. PMID- 4285673 TI - Tumors of the vulva and vagina. Sweat gland tumors. PMID- 4285672 TI - [Quantitative animal experiments on the transport of dust from the lungs to the regional lymph nodes]. PMID- 4285674 TI - Radiotherapy for salivary gland tumours. PMID- 4285675 TI - The intracellular localization of heme by a fluorescence technique. AB - A new technique for the intracellular localization of minute amounts of heme and hemoproteins is described. The specimen is treated with 1.5 M perchloric acid in the presence of SH groups, followed by ultraviolet light irradiation in a fluorescence microscope. This fixes the proteins in situ and converts the heme to a porphyrin which fluoresces and is readily visualized. With this technique, hemoglobin has been demonstrated in the nuclei of avian erythrocytes, and in the nuclei of human normoblasts at an earlier stage than previously described. In addition, hemoproteins, presumably cytochromes, have been detected in the cytoplasm and nuclei of myelocytes, in thymus lymphocyte nuclei, in chick embryo liver cytoplasm, and in chick embryo somites. PMID- 4285676 TI - [Separation of arsenic (3), antimony (3), and tin (II) cations by thin-layer chromatography on silica gel G]. PMID- 4285677 TI - Cushing's syndrome associated with anaplastic carcinoma of the thyroid gland. PMID- 4285678 TI - Urinary lactic acid dehydrogenase activity in the diagnosis of urologic neoplasms. PMID- 4285679 TI - Influence of urine on viruses. PMID- 4285681 TI - Multiple granular-cell myoblastoma of the tongue. Report of a case. PMID- 4285680 TI - [Hepatoma occurring in animals following the ingestion of peanut feed or of cereals contaminated by fungi and especially Aspergillus flavus]. PMID- 4285682 TI - [Case of malignant thecoma]. PMID- 4285683 TI - Adrenocortical nuclear volume and adrenocortical function. PMID- 4285684 TI - Effect of neonatal thymectomy on endocrine and lymphatic organs, reticular elements and blood count. I. Findings in rats not suffering from wasting syndrome. PMID- 4285685 TI - [Ethyl monoiodostereate. Preparation and analytical characteristics]. PMID- 4285686 TI - [Exploration of arterial hypertension by the angiotensin test]. PMID- 4285687 TI - Rate-limiting factors in glycolysis and transport of inorganic phosphate in DBAH 1 tumor, DBAG tumor, Novikoff hepatoma, and Novikoff ascites tumor. PMID- 4285688 TI - Serum protein-bound fucose in patients with breast masses. PMID- 4285689 TI - The incidence of cancer in quantitatively transplanted mammary glands and its relation to age and milk agent of the donor and host mice. PMID- 4285690 TI - Liver response tests. I. Exploratory studies on glucose 6-phosphatase and other liver enzymes. PMID- 4285692 TI - A study of the effects of zinc and tin administered orally to mice over a prolonged period. PMID- 4285691 TI - Liver response tests. II. Effect of coumarin on glucose 6-phosphate metabolism in rat liver. PMID- 4285694 TI - Physiological role of the adrenal medulla in the palmar anhidrotic response to stress. PMID- 4285693 TI - Cellular physiology of cold- and heat-exposed squirrel monkeys (Saimiri sciurea). PMID- 4285696 TI - [Myoblastomas in otorhinolaryngology]. PMID- 4285695 TI - [Giant foliated fibroadenoma (cystosarcoma phyllodes)]. PMID- 4285697 TI - The role of the thymus in carcinogenesis. PMID- 4285699 TI - [Study of the inactivation of angiotensin II by plasma of normal subjects and of hypertensive subjects]. PMID- 4285698 TI - [Effect of ACTH, hydrocortisone and adrenalectomy on the morphology and some histochemical reactions of the brown adipose tissue in the white rat]. PMID- 4285700 TI - [95 nerve wounds in children. Immediate suture]. PMID- 4285701 TI - [4 langerhansian adenomas]. PMID- 4285702 TI - Effect of IDU on DNA synthesis. During corneal wound healing. PMID- 4285703 TI - A simple and sensitive enzymic method for determination of L(+)-lactic acid. PMID- 4285704 TI - Separation and detection of organic acids on silica gel. PMID- 4285705 TI - Experimental study of bronchographic media on lung. PMID- 4285706 TI - Hyperuricemia induced by drugs. PMID- 4285707 TI - Actions of isoniazid on NADH dehydrogenase activity of kidney of tuberculous guinea pigs. PMID- 4285708 TI - Histophysiological investigation on the zonation, activity, and mode of secretion of the adrenal gland of the frog, Rana temporaria Linnaeus. PMID- 4285709 TI - [Thin-layer chromatography of some etiocholenic acids resulting from oxidation of corticosteroids]. PMID- 4285710 TI - The separation and detection of organo phosphate pesticides using diphasic paper chromatography. PMID- 4285711 TI - An electrophorectic method for the detection and estimation of microgramme quantities of neomycin serum protein solutions. PMID- 4285712 TI - Herpes simplex virus in ocular, nasal, and oral secretions of patients with herpetic keratitis. PMID- 4285713 TI - [Microrefractometric modifications as early manifestations of harmful actions on Entamoeba histolytica in culture]. PMID- 4285714 TI - [Determination of cytochrome-c oxidase in eggs, larvae and pupae of the SRS strain of Musca domestica L]. PMID- 4285715 TI - The association of aniridia, Wilms's tumor, and genital abnormalities. PMID- 4285716 TI - Analysis of 5-HTP-C-14 and its metabolites. PMID- 4285717 TI - [On the effect of polysilicic acid and quartz on the erythrocyte membrane]. PMID- 4285718 TI - Viral ribonucleic acid polymerase: chick-embryo cells infected with vesicular stomatitis virus or Rous-associated virus. PMID- 4285719 TI - Hormonal dependence of actidione (cycloheximide) action. PMID- 4285720 TI - Intratracheal injection into rats of size-graded silica particles. PMID- 4285721 TI - Prevention of denervation in Bell's palsy. PMID- 4285722 TI - [Abrikosv's granulo-cellular tumor. Cutaneous localization]. PMID- 4285723 TI - Comparative study of the activity of the synthetic corticotropin-beta-1-24. PMID- 4285724 TI - [Studies on the new test of pathogenic activity of silica]. PMID- 4285725 TI - Oxidation and peroxidation. PMID- 4285726 TI - On the mechanism of respiratory control. AB - Control of oxidation is the key mechanism in the regulation of energy metabolism. In glycolysis the oxidation of glyceraldehyde-3-phosphate is controlled by DPNH, which inhibits glyceraldehyde-3-phosphate dehydrogenase. In oxidative phosphorylation the inhibition of electron flow from DPNH to oxygen, called "respiratory control," is the subject of this paper. After a discussion of the physiological significance of the "tight coupling" between phosphorylation and oxidation, studies on "loosely coupled" submitochondrial particles are reported. These particles are capable of oxidative phosphorylation in the presence of a suitable phosphate acceptor system, but in contrast to controlled, intact mitochondria they oxidize DPNH in the absence of phosphate and ADP. The addition of o-phenanthroline to submitochondrial particles gives rise to an inhibition of respiration, which is partly reversed by phosphate and ADP or by dinitrophenol. The properties of this model system of respiratory control will be described. PMID- 4285727 TI - Reaction of oxygen with the respiratory chain in cells and tissues. AB - This paper considers the way in which the oxygen reaction described by Dr. Nicholls and the ADP control reactions described by Dr. Racker could cooperate to establish a purposeful metabolic control phenomenon in vivo. This has required an examination of the kinetic properties of the respiratory chain with particular reference to methods for determinations of oxygen affinity (K(m)). The constant parameter for tissue respiration is k(1), the velocity constant for the reaction of oxygen with cytochrome oxidase. Not only is this quantity a constant for a particular tissue or mitochondria; it appears to vary little over a wide range of biological material, and for practical purposes a value of 5 x 10(7) at 25 degrees close to our original value (20) is found to apply with adequate accuracy for calculation of K(m) for mammalia. The quantity which will depend upon the tissue and its metabolic state is the value of K(m) itself, and K(m) may be as large as 0.5 microM and may fall to 0.05 microM or less in resting, controlled, or inhibited states. The control characteristic for ADP may depend upon the electron flux due to the cytochrome chain (40); less ADP is required to activate the slower electron transport at lower temperatures than at higher temperatures. The affinity constants for ADP control appear to be less dependent upon substrate supplied to the system. The balance of ADP and oxygen control in vivo is amply demonstrated experimentally and is dependent on the oxygen concentration as follows. In the presence of excess oxygen, control may be due to the ADP or phosphate (or substrate), and the kinetics of oxygen utilization will be independent of the oxygen concentration. As the oxygen concentration is diminished, hemoglobin becomes disoxygenated, deep gradients of oxygen concentration develop in the tissue, and eventually cytochrome oxidase becomes partially and then completely reduced. DPN at this point will become reduced and the electron flow diminished. The rate of ATP production falls and energy conservation previously under the control of the ADP concentration will now be controlled by the diffusion of oxygen to the respiratory enzymes in the mitochondria. Under these conditions the rate of reaction of cytochrome oxidase with oxygen and the reaction of cytochromes with one another become of key importance. The rise of ADP and the depletion of energy reserves evoke glycolytic activity, and failure of biological function may result. PMID- 4285729 TI - Autologous implantation of rhesus monkey cells "transformed" in vitro by simian virus 40. PMID- 4285730 TI - Malignant islet cell adenoma in a pancreatic cyst. Report of a case. PMID- 4285728 TI - Copper proteins and oxygen. Correlations between structure and function of the copper oxidases. AB - A comprehensive survey of the interaction of the copper proteins and oxygen is presented including a correlation of structure, function, and other properties of the known copper oxidases and of hemocyanin. The origin of their blue color and the structure of copper complexes and copper proteins are related to the oxidation state of copper ion and relevant electronic transitions probably arising from the formation of charge transfer complexes. The oxygen reactions of hemocyanin, ceruloplasmin, and cytochrome oxidase show half-saturation values far below the other Cu enzymes. The formation of hydrogen peroxide as a reaction product is associated with the presence of one Cu atom per oxidase molecule or catalytic system. Water is the corresponding product of the other Cu oxidases with four or more Cu atoms per molecule, except for monoamine oxidase. Mechanisms for the oxidase action of the two and four electron transfer Cu oxidases and tyrosinase are proposed. These reactions account for the number, the oxidation reduction potential, and the oxidation state of Cu in the resting enzyme, the cyclical change from Cu(II) to Cu(I), the diatomic nature of O(2), the sequence of the oxidation and reduction reactions, and other salient features. The catalytic reactions involved in the oxidation of ascorbic acid by plant ascorbate oxidase, ceruloplasmin, and Cu(II) are compared. Finally the substrate specificity, inhibitory control, and the detailed mechanism of the oxidase activity of ceruloplasmin are summarized. PMID- 4285731 TI - [Variability of strains of Japanese encephalitis virus in regard to the pH dependency in hemagglutination]. PMID- 4285732 TI - [Incomplete growth of simian virus 40 in African green monkey kidney cell culture induced by serial undiluted passages]. PMID- 4285733 TI - [Studies on SV 40-tumor antigen by means of fluorescent antibody method]. PMID- 4285734 TI - [Pathological aspects of SV40 tumor with special reference to its malignancy]. PMID- 4285735 TI - [Study of liver function in patients treated with lipiodol F I-131 (preliminary observations)]. PMID- 4285736 TI - [The management of idiopathic polyneuritis]. PMID- 4285737 TI - Enzymic studies on the mechanism of double hydroxylation. PMID- 4285738 TI - [Interpretation of the corticotropin adrenal stimulation test]. PMID- 4285739 TI - [Efficacy of griseofulvin in painful neuro-rheumatologic syndromes]. PMID- 4285740 TI - Oxy-coenzyme A: a competitive inhibitor of coenzyme A in the phosphotransacetylase reaction. PMID- 4285741 TI - [A case of facial paralysis caused by adenovirus type 5 infection]. PMID- 4285742 TI - Isolation of different-sized substrains from three stock cultures of Entamoeba histolytica, with observations on spontaneous size changes affecting whole populations. PMID- 4285743 TI - Free amino acid analyses of 4 strains of Entamoeba histolytica and of E. invadens in the CLG medium. PMID- 4285745 TI - Bilateral mixed tumor of the parotid initially regarded as pharyngeal neoplasm. PMID- 4285744 TI - Case records of the Massachusetts General Hospital. Case 10-1966. PMID- 4285746 TI - [Elimination of metabolites of tryptophan in neurologic diseases of the child. 2. Action exercised by ACTH and pyridoxin on urinary elimination of kynurenine derivatives]. PMID- 4285747 TI - The pathogenicity of the small race of Entamoeba histolytica to splenectomized rats. PMID- 4285748 TI - An assay for cellular transformation by SV40. PMID- 4285749 TI - Structure of virus particles, partially purified from the blood of leukemic mice. PMID- 4285750 TI - [Studies on virus-chromosome relationships. VI. Karyotypic study of Shope papilloma]. PMID- 4285751 TI - [Study of mutants of foot-and-mouth disease virus obtained by cultivation at low temperature. Selection of strains non-pathogenic in swine]. PMID- 4285752 TI - Antiviral activity of gliotoxin. PMID- 4285753 TI - Anaphylaxis in pregnant and mother mice following active and passive sensitization. PMID- 4285754 TI - Bovine enteric cytopathogenic viruses. 3. Neutralization studies with animal sera. PMID- 4285755 TI - An indirect hemagglutination test for detecting antibody to infectious bovine rhinotracheitis virus. PMID- 4285756 TI - Variants of myxovirus parainfluenza-3 isolated from calves clinically affected with shipping fever. PMID- 4285757 TI - [Studies on the renin-angiotensin-aldosterone system, especially their roles in the humoral regulating system and the cause of hypertension]. PMID- 4285758 TI - [Theca cell feminizing tumor of the ovary and electroencephalographic disturbances in a three year old child]. PMID- 4285759 TI - [Present problems of therapy of trophoblastic tumors]. PMID- 4285760 TI - [Diagnosia and therapy of some chronic infections in obstetrics (toxoplasmosis, Listeria infections, cytomegalic disease)]. PMID- 4285761 TI - Treatment of Pseudomonas keratitis in rabbits. PMID- 4285762 TI - Histologic changes in clinically normal breasts at postmortem examination. PMID- 4285763 TI - Hormonal induction of ceruloplasmin in chicken serum. PMID- 4285764 TI - Antigenic comparison of two substrains of Entamoeba histolytica by gel diffusion and immunoelectrophoresis. PMID- 4285765 TI - [Apropos of 220 systematic detections of abnormal hemoglobins in Abidjan]. PMID- 4285766 TI - [Anguillulosis in Tropical Africa. Experimentation with a broad spectrum anti amebic drug]. PMID- 4285767 TI - [Interferon: studies in vitro in relation to poliomyelitis and acute leukemia]. PMID- 4285768 TI - A new virus isolated from the human respiratory tract. PMID- 4285769 TI - Non-specific hemadsorption by rhesus monkey kidney cells. PMID- 4285770 TI - Neutralizing antibodies to simian virus 40 (SV40) in human sera from India. PMID- 4285771 TI - [Stevens-Johnson syndrome (erythema multiforme exudativum) in children. Report of 2 cases with survival]. PMID- 4285772 TI - The mobilization of fatty acids from adipose tissue by pituitary peptides and catechol amines. PMID- 4285773 TI - Effect of glucose on spontaneous limitation of lipolysis in isolated adipose tissue: a potential regulatory mechanism. PMID- 4285774 TI - Acute effects of corticotropin and related peptides on carbohydrate and lipid metabolism. PMID- 4285775 TI - Effect of ACTH on FFA release and diglyceride content in perfused rat adipose tissue. PMID- 4285776 TI - Modulation of lipolysis in adipose tissue by fatty acid concentration in fat cell. PMID- 4285777 TI - Physiologic and morphologic microcirculatory responses in humans. PMID- 4285778 TI - Seasonal variations in calcium, inorganic phosphate and alkaline phosphatase contents of Ophicephalus punctatus Bloch. PMID- 4285779 TI - [Contribution to the epidemiologico-virologic study of the adenoviruses]. PMID- 4285780 TI - The conservative surgical treatment of arrhenoblastoma. Report of a case. PMID- 4285781 TI - [Angiography in 3 cases of pancreatic insuloma]. PMID- 4285782 TI - [On the enzymo-histologic characteristic of cancers of the liver. I. Studies of the activity of alkaline phosphatase, acid phosphatase, lipase and nonspecific esterase]. PMID- 4285783 TI - Pathogenicity of the M and E variants of the encephalomyocarditis (EMC) virus. I. Myocardiotropic and neurotropic properties. PMID- 4285784 TI - [Effect of hormones on the activity of "adrenalin oxidase" on the blood serum in vivo]. PMID- 4285785 TI - [Observation on the side effects of ACTH and corticoids]. PMID- 4285786 TI - [Glucocorticoid basopenia]. PMID- 4285787 TI - The nature and control of infections in patients with acute leukemia. PMID- 4285788 TI - [Apropos of neurologic sequelae in gastriectomized patients (peripheral neuropathy with hyperchronic macrocytic anemia]. PMID- 4285789 TI - Urinary cortisol metabolites in adrenocortical hyperfunction. PMID- 4285790 TI - [The renin-angiotensin system]. PMID- 4285791 TI - [Morphologico-histogenetic classification of the blastomas of the nervous system (according to Del Rio-Hortega, slightly modified by Polak, 1964)]. PMID- 4285792 TI - Cloacogenic anorectal carcinoma. PMID- 4285793 TI - Influence of collagenase on collagen metabolism in IF mice. PMID- 4285794 TI - Polymannoheptose isolated from cell wall of uridine diphosphate glucose pyrophosphorylase-less mutant of Escherichia coli K 12. PMID- 4285795 TI - Histochemical demonstration of the soluble enzyme, ketose reductase (sorbitol dehydrogenase), by utilizing a new fixing solution. PMID- 4285796 TI - [Adsorption of Japanese encephalitis virus hemagglutinin on to goose red cells]. PMID- 4285797 TI - [The pathological studies on oncogenesis of hamster tumors induced by SV40]. PMID- 4285799 TI - [Effect of hypothermia on the regeneration of peripheral nerves. (Experimental study)]. PMID- 4285798 TI - Effects of neonatal thymectomy on polyoma tumor formation. PMID- 4285800 TI - The effect of mechlorethamine and cyclophosphamide on the nicotinamide-adenine dinucleotide glycohydrolase activity in Ehrlich ascites cells and L1210 leukemia cells. PMID- 4285801 TI - A new method for the determination of cyanhydric acid and cyanides in the air and in biologic products. PMID- 4285802 TI - The correlations between multiple congenital malformations and the cytomegalic inclusion disease. PMID- 4285803 TI - [Experiences with ACTH treatment of multiple sclerosis]. PMID- 4285804 TI - [Osteoma spongiosum of the 4th lumbar vertebra]. PMID- 4285805 TI - Colitis cystica profunda. PMID- 4285806 TI - Pleural calcification as a sign of silicatosis. PMID- 4285807 TI - A new method for the determination of deoxyribonucleic acid. PMID- 4285808 TI - Different pattern of elution of poliovirus strains from DEAE-cellulose and aluminium hydroxide gel. PMID- 4285809 TI - Ionic effects on glutamate dehydrogenase activity from beef liver, lobster muscle and crab muscle. PMID- 4285810 TI - [On the use of silicon impression materials for partial prosthesis models. (A practicable control possibility for dimension maintenance]. PMID- 4285811 TI - Relationship between the pituitary gland and the corticosteroid-binding globulin in the rat. PMID- 4285812 TI - Effects of 1-methyl-2-mercaptoimidazole and perchlorate on the insulin-mediated enhancement of 131-I incorporation into iodoamino acids by fetal thyroid glands in organ culture. PMID- 4285813 TI - Effect of ACTH on cardiac glycogen. PMID- 4285814 TI - Association of adrenocorticotropic hormone activity with small secretory granules from rat anterior pituitary glands. PMID- 4285815 TI - [Syntheses in the polymyxin series. 9. Synthesis of polymyxin B-1]. PMID- 4285816 TI - Cystosarcoma phyllodes. PMID- 4285817 TI - [Observation on the analysis of fatty substances. II. On the determination of glycerol]. PMID- 4285818 TI - Bilateral Wilms' tumor, including report of a patient surviving ten years after treatment. PMID- 4285819 TI - Apparent bone age in cancer. PMID- 4285820 TI - Direct irradiation of lymph nodes with I-131 tagged ethiodol. PMID- 4285821 TI - 2-keto-3-deoxygalactonic acid as a constituent of an extra-cellular polysaccharide of Azotobacter vinelandii. PMID- 4285822 TI - On the stimulation of testicular steroidogenesis in the rabbit by interstitial cell-stimulating hormone. PMID- 4285823 TI - Antilipolytic effect of insulin in isolated fat cells of the rat. PMID- 4285824 TI - Adrenocortical response to stress and ACTH in Pacific salmon (Oncorhynchus tshawytscha) and steelhead trout (Salmo gairdnerii) at successive stages in the sexual cycle. PMID- 4285825 TI - Induction of permanent diabetes in rats by pituitary hormones from a transplantable mammotropic tumor. Concomitant changes in organ weights and the effect of adrenalectomy. PMID- 4285826 TI - Chemotherapy of malignant brain tumors. PMID- 4285827 TI - A non-traditional role of the nurse: the psychiatric nurse in the community. PMID- 4285828 TI - Teaching adolescent management in a state hospital. PMID- 4285829 TI - Just start with a little T. L. C. PMID- 4285830 TI - Nursing dress, an experimental evaluation of its effect on psychiatric patients. PMID- 4285832 TI - An American nurse's experience in a therapeutic community in Scotland. PMID- 4285831 TI - Role playing as a device to assist long-term patients nearing discharge. PMID- 4285833 TI - The thirteenth stair. PMID- 4285835 TI - Dry skin and its treatment. PMID- 4285834 TI - International trends. Organization of psychiatric rehabilitation in Poland. PMID- 4285836 TI - Geriatrics. PMID- 4285837 TI - [Adenoma of the trachea and bronchus. Statistical studies of 60 patients reported in Japan]. PMID- 4285838 TI - Angiotensin sensitivity in experimental uteroplacental ischemia. PMID- 4285839 TI - The effect of angiotensin II on the sensitivity of the parotid gland of the sheep to aldosterone. PMID- 4285840 TI - Liver glucose-6-phosphatase and pyrophosphate-glucose phosphotransferase: effects of fasting. PMID- 4285841 TI - [Isolation of poliomyelitis virus from throat swabs in a rural community]. PMID- 4285842 TI - Nicotinic acid biosynthesis in prototrophs and tryptophan auxotrophs of Saccharomyces cerevisiae. PMID- 4285843 TI - Beef heart malic dehydrogenases. IV. Fluorescent binary and ternary complexes of the supernatant enzyme. PMID- 4285844 TI - Beef heart malic dehydrogenases. V. A kinetic study of the reaction catalyzed by the supernatant enzyme. PMID- 4285845 TI - Stimulation of metabolism of rat brown adipose tissue by addition of lipolytic hormones in vitro. PMID- 4285846 TI - Investigation of myosin heterogeneity observed during chromatography on diethylaminoethyl cellulose. PMID- 4285847 TI - Biosynthesis of mannophospholipids by Mycobacterium phlei. PMID- 4285848 TI - Biological mechanisms involved in the formation of deoxysugars. 3. Enzymatic conversion of thymidine diphosphoglucose-3T to thymidine diphospho-L-rhamnose. PMID- 4285849 TI - Studies on cytochrome oxidase. II. A reaction of cyanide with cytochrome oxidase in soluble and particulate forms. PMID- 4285850 TI - The metabolism of coumarin by a microorganism. V. Melilotate hydroxylase. PMID- 4285851 TI - The chemistry of lipids of posthemolytic residue or stroma of erythrocytes. XIV. Chemical structure of glycolipid of cat erythrocyte stroma. PMID- 4285852 TI - [Unidentifiable questionable enteroviruses in a nursery]. PMID- 4285853 TI - Structure of a rhamnolipid from Pseudomonas aeruginosa. PMID- 4285854 TI - Hypoglycemia due to obstruction of pancreatic excretory ducts by carcinoma. PMID- 4285855 TI - Functional islet tumor cured by surgical excision. PMID- 4285856 TI - [Lymphographic findings in malignant lymph node disorders]. PMID- 4285857 TI - Clinical applications of nerve conduction velocity. PMID- 4285858 TI - The effect of hydrocortisone and x-irradiation on the lymphocytosis induced by Bordetella pertussis. AB - 1. In mice rendered lymphocytopenic by X-irradiation or hydrocortisone acetate, pertussis vaccine evoked both lymphocytosis and polymorphonuclear leukocytosis. 2. When mice with lymphocytosis induced by pertussis vaccine were X-irradiated, prompt and extensive destruction of circulating as well as tissue small lymphocytes occurred. The devitalized circulating cells were cleared from the blood primarily by the Kupffer's cells of the hepatic sinusoids. 3. Hydrocortisone acetate administered to mice with lymphocytosis did not cause acute lymphopenia nor was there any evidence of destruction of circulating small lymphocytes. However, destruction of these cells within lymphoid tissues was apparent. These observations suggested that adrenal cortical hormones are not "lymphocytolytic" with respect to circulating lymphocytes. PMID- 4285859 TI - The influence of certain hormones and chemicals on mammalian pigment cells. PMID- 4285860 TI - Glucose and glycogen metabolism in the human epidermis. PMID- 4285861 TI - Carbohydrate metabolism in psoriasis: an enzymatic study. PMID- 4285862 TI - Orthostatic hypotension. PMID- 4285863 TI - [The significance of the keton bodies in myocardial metabolism]. PMID- 4285864 TI - Acromegaly pre- and postpituitary irradiation. PMID- 4285865 TI - A diabetogenic polypeptide from bovine adenohypophysis similar to that excreted in lipoatrophic diabetes. PMID- 4285866 TI - Studies of adrenocortical function of women with hirsutism: response to 5 units of ACTH. PMID- 4285867 TI - [Physiochemical properties of the polyoma virus in relation to its biological activity]. PMID- 4285868 TI - Functioning neural tumors. PMID- 4285869 TI - [Polymorphism of a human urophosphatase]. PMID- 4285870 TI - [Apropos of 42 cases of salivary gland tumors]. PMID- 4285871 TI - Insulin-secreting adenoma of the pancreas. PMID- 4285872 TI - [Contributions to the enzyme changes before and after therapy in chronic potassium-deficient nephritis]. PMID- 4285873 TI - The preparation of 1-O-tosyl-(--)-inositol from quebrachitol. PMID- 4285875 TI - Pyridine nucleotide oxidizing enzymes of Lactobacillus casei. I. Diaphorase. PMID- 4285874 TI - Studies on the acetoacetate-like compound found in dystrophic mouse muscle homogenates. PMID- 4285876 TI - Pyridine nucleotide oxidizing enzymes of Lactobacillus casei. II. Oxidase and peroxidase. PMID- 4285878 TI - Liver alcohol dehydrogenase as a 3-beta-hydroxy-5-beta-cholanic acid dehydrogenase. PMID- 4285877 TI - Phosphopeptides: synthesis and enzymic studies. PMID- 4285879 TI - [Influence of intravenous perfusion of angiotensin II on the urinary elimination of sodium in edematous cardiac patients]. PMID- 4285880 TI - Chemical synthesis of N-acetylgalactosamine-alpha I-phosphate 6-O-sulphate, N acetylchondrosine sulphate and UDP-N-acetylgalactosamine 6-O-sulphate. PMID- 4285881 TI - Studies on the structure of neuramin-lactose sulfate. PMID- 4285882 TI - The dissolution and fractionation of bovine sclera. PMID- 4285883 TI - The production of hyaluronate by spontaneously established cell lines and viral transformed lines of fibroblastic origin. PMID- 4285885 TI - Characterization of HeLa cell and viral ribonucleic acid by oligonucleotide analysis. PMID- 4285884 TI - Changes in the activity of rat adrenal ribonuclease and ribonuclease inhibitor after administration of corticotrophin. PMID- 4285887 TI - "B" virus disease in monkey and man. PMID- 4285888 TI - [Non-defectivity of the Rous Schmidt-Ruppen virus strain]. PMID- 4285886 TI - Retention by membrane filters of phosphatase-produced deoxyadenosine in DNA polymerase assay. PMID- 4285889 TI - Myocardial function (studied using angiotensin) after aortic homograft valve replacement. PMID- 4285890 TI - Heterogeneity of liver alcohol dehydrogenase on starch-gel electrophoresis. AB - 1. Purified horse-liver alcohol dehydrogenase is heterogeneous on starch-gel electrophoresis in several buffer systems. 2. The electrophoretic pattern is altered by the addition to the buffers of oxidized or reduced coenzymes, isobutyramide, metal ions or metal-chelating agents. 3. The effect of coenzymes on the pattern suggests that the major cause of the observed heterogeneity is not the existence of isoenzymes, but the presence in the enzyme preparations of coenzyme-enzyme complexes or complexes with other nucleotides similar to, but less reactive than, the coenzymes. 4. Metal ions and chelating agents influence the electrophoretic separation by partial denaturation and inactivation of the enzyme. PMID- 4285891 TI - The purification and properties of the alanyl-transfer ribonucleic acid synthetase of tomato roots. AB - 1. The alanyl-s-RNA synthetase of tomato roots has been purified by ammonium sulphate precipitation, adsorption on calcium phosphate gel and DEAE-cellulose chromatography and its properties have been investigated. 2. Enzyme activity was measured by using the hydroxamate assay, the [(32)P]pyrophosphate-ATP-exchange assay and the [(14)C]alanyl-s-RNA assay. The purified enzyme was specific for l alanine and was activated by Mg(2+) ions and to a smaller extent by Co(2+) and Mn(2+) ions. It was free from adenosine triphosphatase, pyrophosphatase and ribonuclease, and possessed a specific activity comparable with that of the most highly purified aminoacyl-s-RNA synthetases from animal and microbial systems. 3. The properties of the purified enzyme were similar in many respects to most other highly purified aminoacyl-s-RNA synthetases. It differed, however, in that the pH optimum of the hydroxamate assay was almost the same as that of the pyrophosphate ATP-exchange assay and in requiring a high concentration of l-alanine for maximum activity (100mumoles/ml.). 4. The purified enzyme was not absolutely specific for tomato-root s-RNA; slight activity was also observed with yeast s-RNA. 5. The properties of this enzyme are fully consistent with the suggestion that the enzymic formation of alanyl-s-RNA proceeds via the intermediate formation of alanyl acyl-adenylate with the elimination of pyrophosphate from ATP. It remains to be shown the extent to which alanyl-s-RNA participates further in subsequent stages of protein synthesis in plants. PMID- 4285892 TI - Diphosphoinositide and triphosphoinositide in animal tissues. Extraction, estimation and changes post mortem. AB - 1. A method is presented for the determination of the di- and tri phosphoinositide in animal tissues. 2. The polyphosphoinositides are quantitatively extracted into chloroform-methanol-hydrochloric acid solvent after a preliminary chloroform-methanol (1:1, v/v) extraction to remove the bulk of the other phospholipids. On washing this extract with n-hydrochloric acid the polyphosphoinositides pass completely into the lower chloroform-rich phase. Their concentrations in the lower phase are determined by chromatography on formaldehyde-treated paper or chromatography and ionophoresis of the acid hydrolysis products. 3. When guinea-pig brain is extracted by the method of Folch (1942), considerable hydrolysis of the triphosphoinositide and accumulation of diphosphoinositide occurs during the initial acetone extraction. 4. The tri- and di-phosphoinositide contents of rat and guinea-pig brain decline substantially within a few minutes after death. 5. The concentrations of tri- and di phosphoinositide in rat brain are not changed by insulin-hypoglycaemia or electrical stimulation. 6. Examination of frozen rat tissues showed that the brain contained the highest concentration of polyphosphoinositides. Much smaller amounts are present in kidney, and only trace quantities in liver and lung. None could be detected in spleen, heart and skeletal muscle. PMID- 4285893 TI - Polyphosphoinositides in myelin. AB - 1. On fractionation of guinea-pig forebrain homogenates by differential and gradient-density centrifugation most of the polyphosphoinositides were recovered in the myelin-rich particles. 2. The phospholipids of pure preparations of myelin contained di- and tri-phosphoinositide in proportions 2-3 times greater than in the whole-brain phospholipids. 3. Di- and tri-phosphoinositide appeared in young rat brain during the period of myelination. 4. After the administration of [(32)P]phosphate to guinea pigs the labelling of the polyphosphoinositides in isolated pure myelin was as great as in the whole brain, whereas little synthesis of the other myelin phospholipids had occurred. 5. When brain subcellular fractions were incubated with [gamma-(32)P]ATP, some triphosphoinositide labelling occurred in the myelin-rich fraction whereas the active labelling of diphosphoinositide was localized mainly in the mitochondrial fraction. 6. The Na(+), K(+) and Mg(2+) plus Ca(2+) concentrations in purified myelin have been determined. The Mg(2+) plus Ca(2+) content present showed close acid-base equivalence to the polyphosphoinositides. 7. It is concluded that di- and tri phosphoinositide are rapidly-metabolizing components of the myelin sheath or intimately associated structures. PMID- 4285894 TI - The purification and properties of malonic semialdehyde oxidative decarboxylase from Prototheca zopfii. AB - 1. An enzyme, which in the presence of NAD(+) and CoA oxidizes malonic semialdehyde to acetyl-CoA, has been purified from an extract of the colourless alga Prototheca zopfii. 2. The purified enzyme has optimum pH7.5, is specific for NAD(+) and requires a thiol compound for maximum activity. 3. The enzyme is inhibited by arsenite, N-ethylmaleimide and urea. 4. The results are discussed in relation to those obtained by other workers with a similar bacterial enzyme, and a possible reaction sequence is proposed. PMID- 4285895 TI - The mechanism of the periodate-thiobarbituric acid reaction of sialic acids. AB - 1. The chromogen formation from N-acetylneuraminic acid in the periodate thiobarbituric acid reaction was investigated. Measurement of periodate consumption showed an uptake of approx. 3moles/mole of substrate in neutral as well as in strongly acidic solution. Therefore the chromogen beta-formylpyruvic acid is not a direct product of the periodate oxidation; it is presumed to be formed from the true oxidation product, a hexos-5-uluronic acid, by aldol splitting during the reaction in hot acidic solution with thiobarbituric acid. 2. Methyl (methyl beta-l-threo-hexos-4-enepyranosid)uronate, an analogue of the pre chromogen, has been shown to yield with thiobarbituric acid in acidic solution a pigment exhibiting an identical absorption spectrum and showing the same behaviour on paper chromatography as the pigment obtained from N-acetylneuraminic acid in the periodate-thiobarbituric acid assay. 3. The substitution at C-2 of methoxyneuraminic acid does not inhibit the periodate-thiobarbituric acid reaction. In neutral solution methoxyneuraminic acid is oxidized by periodate to a substance that reacts readily with thiobarbituric acid in acidic solution. When periodate oxidation is attempted in acidic solution, protonation of the amino group protects this group against oxidation, rendering methoxyneuraminic acid negative in the assay systems of Warren (1959a,b) and Aminoff (1959, 1961). PMID- 4285896 TI - Nicotinamide nucleotides in the erythrocytes of patients suffering from pellagra. AB - 1. The nicotinamide nucleotide concentrations in the erythrocytes of subjects suffering from pellagra (pellagrins) were not lower than those in normal subjects, but the ability of erythrocytes to synthesize these nucleotides in vitro was significantly lower in pellagrins. 2. The oral administration of 10g. of l-leucine daily for 5 days depressed the nicotinamide nucleotide-synthesizing ability of erythrocytes both in normal subjects and in pellagrins. This was not accompanied by changes in the nucleotide concentration in erythrocytes. 3. Quinolinic acid brought about a significant inhibition of the synthesis of nicotinamide nucleotides in vitro. Such inhibition was partially overcome by increasing the concentration of nicotinic acid in the medium. PMID- 4285897 TI - Spectral and biological changes induced in nicotinic acid and related compounds by ultraviolet light. AB - 1. Irradiation of nicotinic acid, nicotinamide, nicotinamide N-oxide, N'-methyl-4 pyridone-3-carboxamide, reduced nicotinamide-adenine dinucleotide and pyridine with ultraviolet light at 253.7mmu leads to striking spectral changes. 2. Nicotinic acid and nicotinamide are broken down to photosensitive intermediates which in turn undergo photodecomposition. 3. A major photoproduct of [7 (14)C]nicotinic acid is radioactive and absorbs ultraviolet light, but is inactive as a growth factor for Candida pseudotropicalis. 4. Irradiation of nicotinamide gives rise to small quantities of a biologically active photoproduct having the same R(F) as nicotinic acid. A second photoproduct is also formed, but its identity has not yet been established. 5. Irradiation of nicotinamide N-oxide leads to the formation of several photoproducts, one of which has the same R(F) as nicotinamide, absorbs ultraviolet light, and is biologically active. 6. Evidence is presented that irradiation of ethanolic solutions of N'-methyl-4 pyridone-3-carboxamide gives rise to acetaldehyde. 7. Irradiation of reduced nicotinamide-adenine dinucleotide in the presence of acetaldehyde leads to the formation of oxidized nicotinamide-adenine dinucleotide, which in turn can break down to nucleotide and/or nucleoside (depending on the conditions of the reaction). 8. The quantum yields of photolysis and the molar photosensitivities have been determined for N'-methyl-4-pyridone-3-carboxamide and nicotinamide N oxide. 9. The possible biological significance of these photoreactions is discussed in relation to photosynthesis, visual-pigment metabolism and ultraviolet-light-induced cell damage. 10. A four-step theory is presented for the biochemical evolution of oxidation-reduction systems, involving photoactivated transformations of pyridine derivatives. PMID- 4285898 TI - Lysosomes in rat-kidney tissue. PMID- 4285899 TI - Isolation and characterization of collagenases I and II from Clostridium histolyticum. PMID- 4285900 TI - The effect of cyanide on the Keiling-Hartree preparation and purified cytochrome oxidase. PMID- 4285901 TI - WHO collaborative studies on enterovirus reference antisera. AB - This paper summarizes the results of co-operative studies undertaken by the WHO International Reference Centre for Enteroviruses and a number of WHO Regional Reference Centres for viruses, WHO Virus Collaborating Laboratories, or other laboratories in a comprehensive testing programme of enterovirus equine antisera. The studies were designed to appraise the specificity of immune serum prepared in horses against five representative prototype enteroviruses (poliovirus 1, coxsackieviruses A9 and B3, and echoviruses 4 and 11). Tests for neutralizing antibody were performed not only against the homologous viruses, but also against a battery of heterotypic picornaviruses, comprising 63 enteroviruses, several rhinoviruses, and three reoviruses. Each serum sample represented a pool of the individual bleedings taken from groups of five or six horses before and after immunization with each virus antigen (except echovirus 4, for which three animals were immunized). The results showed that, whereas the homologous titres of the antisera (poliovirus 1, coxsackieviruses A9 and B3, echoviruses 4 and 11) were found to be within a useful range (700-8000), heterotypic antibodies of significant titre were not detected. All corresponding pre-inoculation sera were negative. The specificity of the haemagglutination-inhibiting antibody of the coxsackievirus B3 and echovirus 11 antisera was also demonstrated. This accumulated information played a major role in a decision to prepare in horses antisera to the rest of the enterovirus group. Co-operative testing of the other enterovirus equine antisera is now in progress. PMID- 4285902 TI - Childhood cancer in twins. PMID- 4285903 TI - Synovial sarcoma. A review of 58 cases. PMID- 4285904 TI - Some epidemiological features of lung cancer among Jewish males. PMID- 4285905 TI - Melanotic neuroectodermal tumor of infancy--a neoplasm of neural crese origin. Report of a case associated with high urinary excretion of vanilmandelic acid. PMID- 4285906 TI - [The therapy of peripheral neurovegetative irritations (basis, indications, limits)]. PMID- 4285907 TI - Lesions in the temporal bone causing multiple nerve damage. PMID- 4285908 TI - [Morphological indications of exogenous factors in systemic diseases]. PMID- 4285909 TI - [Degenerative diseases of the pyramidal-motor system]. PMID- 4285910 TI - Kinetic studies on the breakdown of adenosine diphosphate in human plasma. PMID- 4285911 TI - Glomus tumor (chemodectoma) of the larynx. PMID- 4285912 TI - Effect of ACTH on the hypothalamic neurosecretion of the pigeon (Columba livia domestica L.). PMID- 4285913 TI - Comparative study on the lactic acid and hexosamine content as well as on the glycolytic and cytochrome oxidase activities of some lower animals. PMID- 4285914 TI - [Sudoriparous epithelioma of the forehead]. PMID- 4285915 TI - Acquired generalized anhidrosis. PMID- 4285916 TI - Malignant disease of the parotid. PMID- 4285917 TI - Studies of an alveolar soft tissue sarcoma. PMID- 4285919 TI - [On the radioresistance of nucleohistone]. PMID- 4285918 TI - The histogenesis of mammary tumours induced in the rat by chemical carcinogens. PMID- 4285920 TI - [Heterograft of diploid human cells transformed in vitro by the Rous sarcoma virus of the chicken (Bryan strain)]. PMID- 4285921 TI - Protection of packaged food from insect infestation by the use of silica gel. PMID- 4285922 TI - Catecholamines and hemodynamic changes in hypertension. PMID- 4285923 TI - On the role of renin-angiotensin system with special relation to aldosterone for the etiology of hypertension. PMID- 4285924 TI - Role of the brain stem in pathogenesis of hypertension. PMID- 4285925 TI - Vascular reactivity in experimental hypertension. PMID- 4285926 TI - On the humoral factors in arterial hypertension. PMID- 4285927 TI - Significance of angiotensinase on renin-angiotensin system. PMID- 4285928 TI - [Corticosterone secretion in man. II. Relation to body weight and body surface. Comparison to cortisol secretion]. PMID- 4285929 TI - NAD biosynthesis as an early part of androgen action. PMID- 4285930 TI - [Behavior of citric acid in the blood serum of children with rickets]. PMID- 4285931 TI - Tumors induced in hamsters by a strain of adenovirus type 3: sharing of tumor antigens and "neoantigens" with those produced by adenovirus type 7 tumors. PMID- 4285932 TI - Prevention of SV40 virus oncogenesis in hamsters. I. Tumor resistance induced by human cells transformed by SV40. PMID- 4285933 TI - Evidence for virus-specific noncapsid proteins in poliovirus-infected HeLa cells. PMID- 4285935 TI - Studies of adenovirus-SV40 hybrid viruses. 3. Transfer of SV40 gene between adenovirus types. PMID- 4285934 TI - Intracellular mitochondrial diversity in various strains of Saccgarintces cerevisiae. PMID- 4285936 TI - The role of interferon in the inhibition of SV40 transformation of mouse cell line 3T3. PMID- 4285937 TI - Nocturnal nephrogenic diabetes insipidus. PMID- 4285938 TI - [Problems of mole degeneration of the chorion (vacuum aspiration a new treatment method for hydatid moles)]. PMID- 4285939 TI - [Congenital hyperplasia of the adrenal glands with loss of salt (Debre-Fibiger syndrome). Trial treatment with aldosterone. Effect of the administration of 17 OH progesterone. Study of the angiotensin test]. PMID- 4285940 TI - [The morphologic and endocrine aspects of adolescence]. PMID- 4285941 TI - Polysaccharides, nucleic acids, and protein of wheat stem rust (Puccinia graminis tritici) urediospores. PMID- 4285942 TI - Biosynthesis of lipids in plants. I. Incorporation of orthophosphate-32P and glycerophosphate-32P into phosphatides of Chlorella vulgaris during photosynthesis. PMID- 4285943 TI - Metabolism in vitro of tritiated adrenocorticotrophic hormone. PMID- 4285945 TI - Estimation and quantification of myocardial contractility in the closed-chest dog. PMID- 4285944 TI - Effect of nutritional state on hormonal regulation of liver enzymes. PMID- 4285946 TI - The effect of pH on the release of free fatty acids and glycerol from adipose tissue stimulated with adrenalin, adrenocorticotropin and glucagon. PMID- 4285947 TI - [Bronchial asthma therapy with glycocorticoids and ACTH on the basis of material of the internal medicine clinics of the Pomeranian Academy of Medicine in Szczecin]. PMID- 4285948 TI - [Complications of lymphography]. PMID- 4285949 TI - [Reaction of the organs of the rat to colloidal silicic acid in the presence of polyvinylpyridine-N-oxide and polyvinylpyrrolidone]. PMID- 4285950 TI - On the surface localization of enzymes in E. coli. PMID- 4285952 TI - Asymmetric dehydration of galactarate by bacterial galactarate dehydratase. PMID- 4285951 TI - Enzymic activity of a cytochrome A preparation free of cytochrome a3 from cardiac muscle. PMID- 4285953 TI - Proteolipids. 3. Protection of lipid-cytochrome c by an antioxidant fraction from beef heart. PMID- 4285954 TI - Histologic changes in the adrenal cortex of hypophysectomized-gonadectomized rats treated with gonadotrophins or adrenocorticotrophin. PMID- 4285955 TI - Response to metyrapone in children with rheumatic diseases. PMID- 4285956 TI - [Endocrinological study on prostatic carcinoma: effects of anti-androgenic treatment on pituitary ACTH reserve function]. PMID- 4285957 TI - [Therapeutic trials of a new bronchodilator product: AC 3810]. PMID- 4285958 TI - Studies on the feed-back regulation of cholesterol synthesis. PMID- 4285959 TI - Some aspects of the development, biology and biochemistry of rat hepatomas of different growth rate. PMID- 4285960 TI - Correlation of enzyme activities and metabolic pathways with growth rate of hepatomas. PMID- 4285961 TI - Synthesis of purines and nucleic acids and catabolism of purines by rat liver and hepatomas. PMID- 4285962 TI - Studies on thymidylate phosphatase, thymidine kinase and thymidylate kinase activities in some transplantable rat hepatomas. PMID- 4285963 TI - Some factors regulating the rate of gluconeogenesis in animal tissues. PMID- 4285964 TI - [On the mechanism of action of a Melilotus preparation]. PMID- 4285965 TI - [Coexistence of hypophosphatasia, necrotic epidermolysis and probable presence of intra-uterine amniotic bands in a premature infant]. PMID- 4285966 TI - [Simian virus (SV) 40]. PMID- 4285967 TI - [In vitro characteristics of polioviruses]. PMID- 4285968 TI - Cytomegalic inclusion disease. PMID- 4285969 TI - Angiotensin and its response in different diseases. PMID- 4285970 TI - Transmission of Mycobacterium leprae to animals. Nerve involvement in the ears of hamsters. PMID- 4285971 TI - Nodular panniculitis and peripheral neuropathy following sudden withdrawal of corticosteroids. (Poststeroid nodular panniculitis). PMID- 4285972 TI - [Angio-renographic studies of ACTH-treated rats after administration of posterior pituitary lobe hormone]. PMID- 4285973 TI - Studies on the Straub diaphorase. I. Isolation of multiple forms. PMID- 4285974 TI - Studies on the Straub diaphorase. II. Properties of an antibody to the Straub diaphorase. PMID- 4285975 TI - Increased specific activity and formation of an inhibitor from the LDH-5 isozyme of lactate dehydrogenase. PMID- 4285977 TI - Synthesis of trinucleoside diphosphates with polynucleotide phosphorylase. PMID- 4285976 TI - Biosynthesis of cell wall polysaccharide in mutant strains of Salmonella. 3. Transfer of L-rhamnose and D-galactose. PMID- 4285978 TI - Synthesis of DL-1,2-dihydroxyhexadecane, DL-erythro-1,2,3,-trihydroxyhexadecane, and DL-1,2-dihydroxy[1,3,4-3H]hexadecane. Metabolism of [1,2-3H]palmitaldehyde and DL-1,2-dihydroxy[1,3,4-3H]hexadecane. PMID- 4285979 TI - Terpene metabolism in the rat testis. II. Metabolism of mevalonic acid by cell free preparations. PMID- 4285980 TI - Histochemical studies on carbohydrate metabolism of the mesencephalic nucleus of the trigeminal nerve in the rat. PMID- 4285981 TI - Cirrhosis and hepatoma in alcoholics. PMID- 4285982 TI - Histochemical study on the Paneth cell in the rat. PMID- 4285983 TI - The interaction of external and internal controls on enzyme levels and hepatoma. PMID- 4285984 TI - Alveolar carcinoma of the lung, encephalitis due to herpes simplex. PMID- 4285985 TI - Pressor hypertension. PMID- 4285986 TI - On the efficiency of oxidative phosphorylation in yeast mitochondria. PMID- 4285987 TI - [Description and demonstration of antibodies against beta 1-24 corticotropin]. PMID- 4285988 TI - The cytopathic effects of tumor viruses in human diploid cells. Similarity with lesions of irradiated cells. PMID- 4285989 TI - [Electron microscopic studies on the orthology and experimental pathology of the cerebellum of the mouse]. PMID- 4285990 TI - [Pancreatic insulinomas sensitive to 1-leucine: glycometabolic findings in two cases before and after surgical removal]. PMID- 4285991 TI - Peripheral neuritis after long-term isoniazid. PMID- 4285992 TI - Angiotensin response in various liver diseases with special reference to liver function tests. PMID- 4285993 TI - Neurovascular compression syndrome of the upper extremity. PMID- 4285994 TI - Mucoepidermoid tumors of the bronchus. PMID- 4285995 TI - [On the ultrastructure of the salivary gland virus in generalized cytomegalic disease]. PMID- 4285996 TI - [The increase in serum albumin in nephrosis responding to therapy]. PMID- 4285997 TI - Autoradiographic localization of the acetylcholine-stimulated synthesis of phosphatidylinositol in the superior cervical ganglion. PMID- 4285998 TI - Studies on the role of protein synthesis in the regulation of corticosterone production by adrenocorticotropic hormone in vivo. PMID- 4286000 TI - [Clinicobiological evolution of duodenal ulcer treated with gefarnate]. PMID- 4285999 TI - Induction of cellular DNA synthesis by polyoma virus. PMID- 4286001 TI - [Metastasizing hepatocholangioma]. PMID- 4286002 TI - [Synthesis and transport of protein components in the Sendai virus]. PMID- 4286003 TI - Analysis of DNA preparations by a variation of the cysteine-sulfuric acid test. PMID- 4286004 TI - A spectrophotometric method for the determination of nucleoside triphosphates (pyrophosphorolysis of nucleoside diphosphate sugars). PMID- 4286005 TI - [Granular cell tumor of the thoracic trachea. Circular tracheal resection with end-to-end suture]. PMID- 4286006 TI - The leukocyte response during viral respiratory illness in man. PMID- 4286007 TI - Recovery of cytomegalovirus from adults with neoplastic disease. PMID- 4286008 TI - A rapid test for adrenocortical insufficiency. PMID- 4286009 TI - Cryofibrinogenemia, multiple dysproteinemias, and hypervolemia in a patient with a primary hepatoma. PMID- 4286010 TI - Nerve motor fiber characteristics in chronic ischemia. PMID- 4286011 TI - A study on the host-tumor relationship, with special reference to protein metabolism. PMID- 4286012 TI - Electron microscopy of transplantable lymphocytic leukemia and reticulum cell sarcoma in C3Hf mivece. PMID- 4286013 TI - Inhibition of tumor growth by new sulfonic acid esters of aminoglycols. PMID- 4286014 TI - Characteristics of an inbred substrain (C3H/HeNSa) of C3H mouse, with reference to the mammary cancer incidence and metastasis. PMID- 4286015 TI - [Theca-granulosa cell tumors. Clinico-pathological study of 18 cases]. PMID- 4286016 TI - Patterns of urinary excretion of steroids in Cushing's syndrome. PMID- 4286017 TI - Remission in Cushing's syndrome with o,p'-DDD. PMID- 4286018 TI - Studies in a patient with an ectopic adrenocortical tumor. PMID- 4286019 TI - Plasma testosterone and urinary 17-ketosteroids in women with hirsutism and polycystic ovaries. PMID- 4286020 TI - Urinary steroid metabolites in children. I. Individual 17-ketosteroids in children with normal sexual development. PMID- 4286021 TI - [Experimental animal studies on the problem of steroid ulcer]. PMID- 4286022 TI - [Islet cell adenoma causing hypoglycemia in a 12-year-old child]. PMID- 4286023 TI - An improved technic for vascular isolation of the liver: experimental study and case reports. PMID- 4286024 TI - Effect of aurovertin on energy-linked processes related to oxidative phosphorylation. PMID- 4286025 TI - [Uses of electron spin resonance (E.S.R.) in the study of radiation effects in vivo]. PMID- 4286026 TI - [Assay of urinary ACTH and its clinical significance]. PMID- 4286027 TI - [Method and significance of blood ACTH bioassay]. PMID- 4286028 TI - [Bioassay and immunoassay of ACTH]. PMID- 4286029 TI - [Posterior pituitary lobe and ACTH secretion]. PMID- 4286031 TI - [Clinical studies on the pituitary ACTH secretory capacity in children by use of an adrenocortical 11-beta-hydroxylase inhibitor (Metopirone). 1. Studies on the fractionation of urinary 17-ketogenic steroids (17-KGS) (using periodate oxidation) and some fundamental aspects of the Metopirone test in children]. PMID- 4286030 TI - [Plasma insulin-like activity and liver damage in diabetics]. PMID- 4286032 TI - [Effects of the corticosteroids treatment on the nucleic acid contents of tumor bearing rat lymphoid tissues]. PMID- 4286033 TI - [Pulmonary lipiodol miliaria. Complications of hysterosalpingography and of vascular accidents]. PMID- 4286034 TI - St. Francis' busy bees. PMID- 4286035 TI - Work sampling--a nursing station study. PMID- 4286036 TI - Carcinomatous neuromyopathies. A review of neurological syndromes associated with malignant neoplasms and unrelated to metastases. PMID- 4286037 TI - Corticoid concentration of plasma in shock and after ACTH administration. PMID- 4286038 TI - Congenital omphalocele in association with cytomegalic inclusion body disease in a newborn child. PMID- 4286039 TI - Effect of magnesium on posterior pituitary hormone action on vascular smooth muscle. PMID- 4286040 TI - Chronic lesions and ACTH: effects of thyroid hormones and electrical stimulation. PMID- 4286041 TI - Rhythmic activity in smooth muscle from small subcutaneous arteries. PMID- 4286042 TI - [On mixed tumors of the parotid gland (clinical contribution)]. PMID- 4286043 TI - [Myoblastoma of the tongue in childhood]. PMID- 4286044 TI - An automated turbidimetric system for antibiotic assay. PMID- 4286045 TI - The application of automated procedures for studying enzyme synthesis in Escherichia coli. PMID- 4286046 TI - The correlation of physical and chemical parameters in pharmacodynamics. PMID- 4286047 TI - The use of the autoanalyzer for the automatic titration of antigenic preparations by means of complement-fixation. PMID- 4286048 TI - The effect of sulphur compounds on free radical reactions and formation in irradiated dry proteins. PMID- 4286049 TI - Adrenocorticotropins. XXXV. The optical rotatory dispersion of sheep adrenocorticotropic hormone in acidic and basic solutions. PMID- 4286050 TI - Early effects of ACTH on adrenal protein synthesis. PMID- 4286051 TI - Observations on phosphorylase activity distribution in the adrenal cortex: effect of ACTH. PMID- 4286052 TI - Surgery of the brachial plexus. Report of a case. PMID- 4286053 TI - Herpes simplex meningo-encephalitis. PMID- 4286054 TI - Treatment of acquired neuropathies. PMID- 4286055 TI - [Study of silicium in animal biology and during atheroma]. PMID- 4286056 TI - [The plasma ACTH. II. Its physiological regulation. Its role in pathology]. PMID- 4286057 TI - [Renin-angiotensin system and hypertension]. PMID- 4286058 TI - Biological properties of rat cells transformed in vitro by Rous sarcoma virus. PMID- 4286059 TI - Syringoma. Histochemical and electron microscopic studies. PMID- 4286060 TI - Ovarian lipoid and theca cell tumors; their origins and interrelations. PMID- 4286061 TI - Attempts to isolate virus from x-ray induced leukemias in the mouse. PMID- 4286062 TI - Viral particles in human breast cancer. PMID- 4286063 TI - [Two cases of the mixed tumor of the palate]. PMID- 4286064 TI - [Intrabronchial foreign bodies. (Experience of a pneumonology department in the Ivory Coast)]. PMID- 4286065 TI - [The action of bradykinin on the activation of secretion of the adrenocorticotropic hormone]. PMID- 4286066 TI - [Reactivation at low temperature of Sabin polioviruses inactivated by ultraviolet rays]. PMID- 4286067 TI - [Genetic reactivation in a group of attenuated variants of polioviruses (Sabin strains)]. PMID- 4286068 TI - [Cultivation, in tissue culture, of L-1 tumor virus isolated from a transplantable mouse lymphosarcoma]. PMID- 4286069 TI - Xanthomatous neuropathy in primary biliary cirrhosis. PMID- 4286070 TI - Effects of severe protein-calorie deficiency on the endocrine control of carbohydrate metabolism. PMID- 4286071 TI - Glioblastoma multiforme involving the posterior fossa. Case report and review of literature. PMID- 4286072 TI - [Congenital cytomegalic disease; a child born in the stage of inactive damage with microcephaly without cerebral calicifications]. PMID- 4286074 TI - Granular-cell myoblastoma of the pituitary. PMID- 4286075 TI - [Difference of immunologic specificity between human male and female urinary phosphatase]. PMID- 4286076 TI - [The formal genesis of Rosenthal fibers]. PMID- 4286073 TI - Renin and angiotensin. A survey of some aspects. PMID- 4286077 TI - [Studies on adrenaline oxidase. II. Effect of hormones in vivo on adrenaline oxidase activity]. PMID- 4286078 TI - [Synovial sarcoma]. PMID- 4286079 TI - [On the increase of the radiosensitivity of desoxyribonucleic acid deprived of purine bases]. PMID- 4286080 TI - [Research on the possibility of synergic effects of 3,4-benzopyrine and the polyoma virus in the newborn mouse]. PMID- 4286082 TI - [Contribution to the epidemiology of parainfluenza II virus in chickens]. PMID- 4286081 TI - Ocular manifestations of hemoglobin S-C disease. AB - Three patients with hemoglobin S-C disease, all with ocular lesions, were studied and contrasted with four other patients who had predominantly either hemoglobin S or C but no ocular lesions. Attention is drawn to the diagnostic value of hemoglobin electrophoresis in such cases. With this technique a diagnosis of hemoglobin S-C disease was made in a patient previously thought to the "Eales' disease"; one sister was found to have asymptomatic hemoglobin S-C disease and unsuspected early ocular lesions. The number of persons in Canada with hemoglobinopathies is increasing. Awareness of an association between abnormal hemoglobins and ocular disease may lead to the recognition of an unsuspected blood disorder or of an unsuspected retinopathy. PMID- 4286083 TI - An analysis of the biphasic response in Rauscher virus disease. PMID- 4286084 TI - Prevention of virus-induced mammary tumors by an orally active pancreas factor. PMID- 4286085 TI - Pathogenicity of Rous virus for adult rats. PMID- 4286086 TI - Immunohistochemical characteristics of insoluble mouse liver cell antigens. PMID- 4286087 TI - [Experiences in the treatment of clinically dysenteric Entamoeba histolytica infections in adults]. PMID- 4286088 TI - [The plasma ACTH. I. Biochemistry; adrenocortical exploration; antigenic properties]. PMID- 4286089 TI - [Obtaining a continuous tissue culture line from human embryonal kidney tissue and study of its sensitivity to prototype enterovirus strains]. PMID- 4286090 TI - [Different possibilities of the use of the hemagglutination and hemagglutination inhibition tests with adenoviruses]. PMID- 4286091 TI - [Study of the nature of the S-marker of poliovirus]. PMID- 4286092 TI - [Intratypic antigenic differences in type I poliovirus]. PMID- 4286093 TI - [Interference of enteroviruses in tissue cultures]. PMID- 4286094 TI - [The formation of virus particles by means of enzyme systems and structural proteins induced by another "helper" virus]. PMID- 4286095 TI - [Attempt to develop a microbiological method of vitamin D-3 determination]. PMID- 4286096 TI - Search for a pressor substance in toxemia of pregnancy. PMID- 4286097 TI - [On two cases of tracheal adenomas with cylindromatous morphology]. PMID- 4286098 TI - Kinetic studies on the thermal degradation of purified poliovirus. PMID- 4286099 TI - Impetigo herpetiformis in two successive pregnancies. PMID- 4286100 TI - A case of carcinoma of an axillary apocrine gland. PMID- 4286102 TI - Electron spin resonance in medical research. PMID- 4286101 TI - [Sensitivity to acidity of aphthous virus strains non pathogenic for swine]. PMID- 4286104 TI - [People who are too small]. PMID- 4286103 TI - [Peripheral neuropathies during the course of malignant hemophathies. Apropos of 4 cases]. PMID- 4286105 TI - [Reflex algodystrophy in neurological diseases]. PMID- 4286106 TI - Neurological complications of dialysis, transplantation, and other forms of treatment in chronic uremia. PMID- 4286107 TI - Effect of corticotropin (ACTH) on experimental seizures. Adrenal independence and relation to intracellular brain sodium. PMID- 4286108 TI - [Alveolar cancer of the lung]. PMID- 4286109 TI - Factors controlling renin in man. PMID- 4286110 TI - Asbestos-related disease. PMID- 4286111 TI - The myocardial effects of acute and chronic usage of ethanol in man. PMID- 4286112 TI - [Acinic cell tumors (acinic cell carcinomas) of the parotid gland]. PMID- 4286113 TI - [Studies on the renal cortex blood flow under the influence of vasopressor substances by means of the Hensel sound]. PMID- 4286114 TI - [A latex slide test for the demonstration of Bordetella pertussis antibodies]. PMID- 4286115 TI - Observations on periodic acid Schiff reaction of primitive blood cells in 86 cases of acute leukemia. PMID- 4286116 TI - Examination and diganosis in patients with head injury. PMID- 4286117 TI - The effects of topical application of phosphate and fluoride solutions on caries incidence and molar surface solubility in Osborne-Mendel rats. PMID- 4286118 TI - Effect of sodium ortho- and pyrophosphate on supragingival calculus. PMID- 4286120 TI - [Analysis of terephthalic acid in biological materials. I. Precipitation with perchloric acid]. PMID- 4286119 TI - [Screening of anti-polio virus activity of benzimidazole derivatives]. PMID- 4286121 TI - [Medico-legal studies on the fetus and the infant. II. Value of the length of tubular skeletons in the estimation of the age of the fetus]. PMID- 4286123 TI - The natural history of mousepox. PMID- 4286122 TI - [Rapid method for the determination of the current degree of virulence in the work on the "Col. SK" poliomyelitis virus (New Haven) in mice]. PMID- 4286124 TI - Mouse hepatitis, reo-3, and the Theiler viruses. PMID- 4286125 TI - Respiratory virus infections of mice. PMID- 4286126 TI - Monilial septicaemia in acute leukaemia. Successful treatment in a case complicated by acute uric acid nephropathy. PMID- 4286127 TI - [Application of a skin allergy test in the diagnosis of adenovirus infections in children]. PMID- 4286130 TI - [Nerve injuries during operations caused by faulty positioning of the patient on the operation table]. PMID- 4286129 TI - Partial hepatectomy for primary hepatoma. PMID- 4286128 TI - [On the determination of the cholinesterase content of human sera by means of indicator paper (Archolest). II. Enzyme content in multiple sclerosis and other neurologic diseases]. PMID- 4286131 TI - Partial hepatectomy for primary hepatoma. PMID- 4286132 TI - Pathogenicity of the M and E variants of the encephalomyocarditis (EMC) virus. II. Lesions of the pancreas, parotid and lacrimal glands. PMID- 4286134 TI - [Mixed tumor of the larynx]. PMID- 4286133 TI - [Parapharyngeal malignant synovialomas. General review and presentation of a case]. PMID- 4286135 TI - [Biologic and biophysical studies on the transformation induced by the polyoma virus]. PMID- 4286136 TI - Nonparticipation of hydrogen peroxide in the cytochrome oxidase reaction. PMID- 4286137 TI - Serum protein binding of vitamin D3. PMID- 4286139 TI - [Cytological picture of tumors of the macroglial type]. PMID- 4286138 TI - Fructose diphosphatase from rabbit liver. IV. Sulfhydryl groups and their relation to the catalytic activity. PMID- 4286140 TI - [The role of hormone preparations in the development of experimental amyloidosis]. PMID- 4286141 TI - [On post-injection infiltrates in adults]. PMID- 4286142 TI - An unusual case of synovial sarcoma. PMID- 4286143 TI - The subcellular distribution of enzymes in type II glycogenosis and the occurrence of an oligo-alpha-1,4-glucan glucohydrolase in human tissues. PMID- 4286144 TI - Studies on the NAD-specific isocitrate dehydrogenase from baker's yeast. PMID- 4286145 TI - The enzymatic isolation and fluoride catalysed racemisation of optically active Sarin. PMID- 4286146 TI - Effect of barbiturates on the non-enzymatic oxidation of reduced nicotinamide adenine dinucleotide catalyzed by flavins. PMID- 4286147 TI - Measurement of the equilibrium constant of the reaction between cytochrome c and cytochrome a. PMID- 4286148 TI - Prolongation of lifespan in the old rat by adrenal and neurohypophyseal hormones. PMID- 4286150 TI - Some characteristics of the virus responsible for osteopetrosis in chickens. PMID- 4286149 TI - The influence of hormone changes during pregnancy on the velocity of collagen aging. PMID- 4286152 TI - Haemagglutination in the typing of enteroviruses. PMID- 4286151 TI - A cytopathic virus causing a transmissible gastroenteritis in swine. II. Biological and serological studies. PMID- 4286153 TI - The excretion of type 1 poliovirus after challenge following primary immunization with quadruple, Salk and Sabin vaccines. PMID- 4286154 TI - An enzyme histochemical and electron microscopical study of the light organ of the glow-worm, Lampyris noctiluca. PMID- 4286155 TI - Some observations upon the histology of the oral mucosa of the albino mouse. PMID- 4286156 TI - Effects of synthetic angiotensin II on catecholamine levels and biological activity. PMID- 4286157 TI - [Determination of amidopyrine, antipyrine and caffeine in mixtures using a volumetric solution of perchloric acid]. PMID- 4286158 TI - Conversion of estradiol-17-beta by sperm preparations of sea urchins and oysters. PMID- 4286159 TI - In vitro corticosteroidogenesis by the duck (Anas platyrhynchos) adrenal. PMID- 4286160 TI - Clostridial septicemia with intravascular hemolysis; a case report. PMID- 4286161 TI - Islet-cell adenomas of the pancreas producing hyperinsulinism. PMID- 4286162 TI - Lipid composition of heart muscle homogenate. PMID- 4286163 TI - Phospholipid composition of chick brain during development. PMID- 4286164 TI - Role of dactinomycin in the improved survival of children with Wilms' tumor. PMID- 4286165 TI - Respiratory arrest associated with intravenous administration of polymyxin B sulfate. PMID- 4286167 TI - [A long term follow-up study of encephalitis japonica--prognostic observations of 43 personal cases fifteen years after the onset]. PMID- 4286166 TI - [Effects of radiation on seeds of Phleum pratense L. Relation between electron spin resonance concentration and radiobiological effects]. PMID- 4286168 TI - [A histopathological study on the residual disturbances after Japanese B encephalitis]. PMID- 4286169 TI - Effect of hypophysectomy or treatment with thyroxine or testosterone on secretory responses and respiratory enzymes of the submaxillary gland of the rat. PMID- 4286170 TI - Granular cell myoblastoma of the bronchus. Case report with a six-year follow-up. PMID- 4286171 TI - [Bio-enzymatic modifications of the hypo- and hyperoxygenated Guerin tumor]. PMID- 4286172 TI - Evidence for a new bacterial collagenolytic enzyme. PMID- 4286173 TI - Long-lived radiation-induced electron spin resonances in an aqueous biological system. PMID- 4286174 TI - Bound pyridine nucleotide of malic-lactic transhydrogenase. PMID- 4286175 TI - The site of diphosphoinositide synthesis in rat liver. PMID- 4286176 TI - Application of the periodate method for the analysis of nucleotide sequence to tobacco mosaic virus RNA. PMID- 4286177 TI - On the heterogeneity of the deoxyribonucleic acid associated with crystalline yeast cytochrome b2. PMID- 4286178 TI - Studies of nucleotide sequences in tobacco mosaic virus. II. The action of spleen phosphodiesterase. PMID- 4286179 TI - Clinical observations on the value of adrenocortical therapy in the Guillain Barre symdrome. PMID- 4286180 TI - [Studies on regional therapy of brain tumors]. PMID- 4286182 TI - A partial purification and characterization of a phosphoanhydride hydrolase (phosphoprotein phosphatase) from the frog egg. PMID- 4286184 TI - A serological survey on natural infection of polyoma virus in experimental animals on Taiwan. PMID- 4286183 TI - The effect of palmityl coenzyme A on glucose 6-phosphate dehydrogenase and other enzymes. PMID- 4286186 TI - Mixed infection of poxviruses in L cells. I. Occurrence of the rescue of dermovaccinia virus by neurovaccinia virus in L cells. PMID- 4286188 TI - [Some factors affecting the multiplication of Japanese B encephalitis virus cultured in HeLa cells and human amnion cells]. PMID- 4286187 TI - [Preliminary study of the phenomenon of persistent infection produced in HeLa cells and human amnion cells by the St. Louis and Japanese B encephalitis viruses]. PMID- 4286189 TI - Lymphangiography: direct and indirect utilizing an iodinated emulsion. PMID- 4286191 TI - Hidradenoma papilliferum. PMID- 4286190 TI - Histochemical localization of esterases, phosphatases and tetrazolium reductases in the motor neurones of the spinal cord of the rat and the effect of nerve division. PMID- 4286192 TI - [Influence of hormones on hepatic biosynthesis of NAD. II. Effect of cortisone]. PMID- 4286193 TI - [Influence of hormones on hepatic biosynthesis of NAD. I. Effect of thyroxin]. PMID- 4286195 TI - Stabilities of metal complexes of phospholipids: Ca(II), Mg(II), and Ni(II) complexes of phosphatidylserine and triphosphoinositide. PMID- 4286194 TI - Biosynthesis of corticoids in guinea pig adrenal slices. [1-14-C]acetate incorporation into adrenal steroids and sterols. PMID- 4286196 TI - Liver response tests. IV. Application to short-term feeding studies with butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA). PMID- 4286197 TI - Liver response tests. VI. Application to a comparative study of food antioxidants and hepatotoxic agents. PMID- 4286198 TI - A clinicopathologic study on the peripheral nervous system of the aged. Sciatic nerve and autonomic nervous system. PMID- 4286200 TI - Ion exchange between alkali metal cations and sodium aluminosilicate gel at 276 degrees, 298 degrees, and 319 degrees K. PMID- 4286201 TI - [Investigations on the pathways of glucose degradation in experimental hepatoma of the rat]. PMID- 4286202 TI - Mechanism of cell transformation by polyoma virus. PMID- 4286203 TI - An experimental study on the effect of reticuloendothelial activity on metastasis and recurrence of tumor. PMID- 4286204 TI - [Vaccination against canine distemper and infectious canine hepatitis. Studies on efficacy and harmlessness]. PMID- 4286206 TI - [Genesis of free radicals in proflavin submitted to the action of visible radiation]. PMID- 4286205 TI - Disruption of mitochondria and solubilization of cytochrome oxidase by a synthetic zeolite. PMID- 4286207 TI - [Dissociation, by irradiation, of the oncogenic and infectious functions of the Rous virus, Schmidt-Ruppin strain]. PMID- 4286208 TI - Treatment of hypsarrhythmia and infantile spasms with a librium analogue. PMID- 4286209 TI - [The manifestations of pancreatic cancer in general medicine]. PMID- 4286210 TI - [Respective value of the cutireaction, the intradermoreaction, the patch test and the multipuncture ring transcutaneous test for the practical detection of natural or postvaccinal tuberculin allergy. (Comparative study on 1,032 patients)]. PMID- 4286211 TI - [Speech disorders caused by bulbar, pseudobulbar, extrapyramidal and cerebellar syndromes]. PMID- 4286212 TI - [A case of bilateral adrenal hematoma occuring during antiocoagulant treatment]. PMID- 4286214 TI - [Inhibitors of hemagglutination by types 1, 2, & 3 parainfluenza viruses]. PMID- 4286215 TI - [On the transfer of infection in mouse hepatitis]. PMID- 4286216 TI - [Application of chromatography to the study of the structure of enteroviruses]. PMID- 4286217 TI - [Trial filtration on "Millipore VM and VF" membranes of a type A7 foot-and-mouth disease virus adapted to mice by intramuscular inoculation]. PMID- 4286218 TI - Observations on production, assay and purification of chick embryo interferon. PMID- 4286219 TI - Chromosomal damage of human cells induced by Sendai virus. PMID- 4286220 TI - The presence of carotid body like structure between the right subclavian and common carotid arteries. PMID- 4286221 TI - Comparative assay of foot-and-mouth disease virus in cattle, mice, and cell cultures. PMID- 4286222 TI - Sensitivity of cell cultures, cattle, mice, and guinea-pigs for detection of nineteen foot-and-mouth disease viruses. PMID- 4286223 TI - Cross-protection product in an attempt of quantitative antigenic differentiation of two foot-and-mouth disease virus strains type O in cattle. PMID- 4286224 TI - Typing of the foot-and-mouth disease virus. PMID- 4286225 TI - A revised list of subtype reference strains of the virus of foot-and-mouth disease held at the World Reference Laboratory, Pirbright, England. PMID- 4286227 TI - [Fibromyoangioma of the mesentery]. PMID- 4286226 TI - Plasma angiotensinase activity in liver disease. PMID- 4286228 TI - Further studies in decompression for inferior alveolar nerve injury. PMID- 4286229 TI - A patient with semi-membranous cyst in leprosy simulating nerve abscess. PMID- 4286230 TI - [Symptomatology of intermittent claudication type in radicular and muscular diseases]. PMID- 4286231 TI - [Harmfulness of poultry feed]. PMID- 4286232 TI - [Lymphography with radioactive lipiodol in Hodgkin's disease]. PMID- 4286233 TI - [The effect of nicotinamide-adenine dinucleotide on the ratio of 17-hydroxy- and 17-dehydroxycorticosteroids synthesized by hog adrenal cortex homogenates]. PMID- 4286234 TI - [Metastases during the development of certain cervico-facial cylindromas]. PMID- 4286235 TI - [Investigation on adenovirus antibodies. 3. Study in a closed community]. PMID- 4286236 TI - [Hemostatic action of estrogens in ORL. Trials of Premarine]. PMID- 4286237 TI - [Klinefelter's syndrome: analysis of gonadal and extragonadal hormonal imbalance]. PMID- 4286238 TI - [Turner-type bilateral gonadal agenesis: unilateral absence of nephrons with well developed wolffian formations, rare carpal malformation, XO/Xx karyotype]. PMID- 4286239 TI - [Testicular feminisation syndrome: presence of a uterus and induced menstruation and a 13-15 autosomic abnormality]. PMID- 4286240 TI - [Simple hypopuberism and bilateral luxation of the elbows with chromosome aberration. (Presence of a small supplementary acrocentric)]. PMID- 4286241 TI - [Clinically inapparent thyroid cancer]. PMID- 4286242 TI - Prognosis in carcinoma of the stomach in relation to the microscopic type. PMID- 4286243 TI - [The inflammatory diseases of the central nervous system]. PMID- 4286244 TI - Titration and neutralization of poliovirus in micro tissue culture under increased carbon dioxide. AB - Modification of the micro tissue culture technique, including incubation under increased CO(2), resulted in prolongation of the viability of the cells. As a consequence, satisfactory titrations of poliovirus and of poliovirus antiserum have been achieved by the micro method. The technique offers a number of advantages over conventional methods. PMID- 4286245 TI - Activity of foot-and-mouth disease virus antiserum after treatment with beta propiolactone to inactivate a contaminating virus. PMID- 4286246 TI - Modification of the procedure to determine the sensitivity of viruses to chloroform. PMID- 4286248 TI - Level and specificity of antibodies evoked by crude and purified antigens of poliovirus I and echovirus 7. AB - Preparations of poliovirus I and echovirus 7, purified by density gradient centrifugation, liquid-phase partition, and anion exchange (diethylaminoethyl) chromatography, have been shown to evoke high antibody levels of substantial specificity in the complement-fixation assay. Certain practical aspects of the three purification methods are discussed. These results argue for the use of purified viral antigens, particularly in view of the simplicity of the purification methods now available. PMID- 4286247 TI - Assay of variola virus by the fluorescent cell-counting technique. AB - A quantitative assay for infective variola virus particles was developed which is based on the enumeration of cells containing fluorescent viral antigen after infection of McCoy cell monolayers. The direct fluorescent-antibody technique was employed to stain cells. The efficiency of virus adsorption was markedly enhanced by centrifugation of virus inoculum onto McCoy cell monolayers at 500 x g for 15 min. By this procedure, a proportionality was obtained between the number of fluorescent cells and volume of inoculum. Observations on the sequential development of viral antigen within cells and counts of fluorescent cells showed that the optimal time for enumerating fluorescent cells was after an incubation period of 16 to 20 hr. A linear function existed between virus concentration and cell-infecting units. Fluorescent cells were distributed randomly in infected cover slip cell monolayers. The assay was demonstrated to be highly sensitive, precise, and reproducible. PMID- 4286249 TI - Continuous cultivation of virus in cell suspensions by use of the lysostat. AB - Theoretical considerations illustrate the feasibility and characteristics of continuous virus cultivation in cell suspensions Physical dimensions of the virus fermentor (lysostat) in relation to optimal yields can be predetermined. Poliovirus type 1 was grown on Hela S-3-1 (Saltzman) cells in a single-stage, percolator-type lysostat, with a yield of 421 TCID(50) per cell. Adenovirus type 14 was grown on KB (Eagle) cells in a two-stage lysostat with a yield of 116 TCID(50) per cell. PMID- 4286250 TI - Sensitivity of agar overlay method for the recognition of enteroviruses. AB - COMPARISON OF THE AGAR OVERLAY TECHNIQUE WITH THE FLUID CULTURE TECHNIQUE FOR ISOLATION AND IDENTIFICATION OF ENTEROVIRUSES SHOWED THE FORMER TO BE USEFUL: (i) for isolation of enterovirus when the number of virus particles was too small to produce detectable cytopathic effect (CPE) in fluid cultures, (ii) for isolation of echovirus 22 which did not produce detectable CPE in fluid cultures, (iii) as an aid to rapid differentiation of enteroviruses, and (iv) for differentiation of viruses in mixed infections. Nonpolio enterovirus isolation experience in the New Haven area over a 4-year period is presented. It was concluded that the agar overlay technique is both useful and relatively simple for routine examination of clinical specimens in a diagnostic laboratory. PMID- 4286251 TI - The pathogenesis of experimental infections with encephalomyocarditis (EMC) virus. PMID- 4286252 TI - Herpes simplex virus and paralysis of animals. PMID- 4286253 TI - Induced upper respiratory infection in the vervet monkey: a model of acute viral respiratory disease in man. PMID- 4286254 TI - Acute transverse myelitis as a complication of glandular fever. PMID- 4286255 TI - Electron spin resonance of free radicals electrochemically generated from polynitroalkanes. PMID- 4286256 TI - Phosphorylase and glucose-6-phosphatase in the African lungfish. PMID- 4286257 TI - [Thin-layer chromatography of amines]. PMID- 4286258 TI - Some applications of paper and vapour-phase chromatography to polysaccharides. Model studies on a synthetic D-mannan. PMID- 4286259 TI - Studies on the mechanism of the vasoconstrictor effect of angiotensin II in man. PMID- 4286260 TI - Effects of isotopic substitution on electron spin resonance signals in photosynthetic organisms. PMID- 4286261 TI - The effect of epinephrine upon subcommissural organ secretion in the rat. PMID- 4286262 TI - [On the therapy of corneal abscess following infection with Pseudomonas pyocyanea]. PMID- 4286263 TI - [Some aspects of the cytological examination of nerve tissue]. PMID- 4286264 TI - Trypsin in resorption of hyphemas. PMID- 4286265 TI - [Report on Brooke-Spiegler phakomatosis]. PMID- 4286266 TI - Anaphylactic antibody in the young rat. PMID- 4286267 TI - The effect of various hormones on the serum level of anaphylactic antibody in the rat. PMID- 4286268 TI - Studies on menadione reductase of bakers' yeast. 3. The identity of menadione reductase with lipoamide dehydrogenase. PMID- 4286269 TI - Glomus tumour of the knee. Report of a case. PMID- 4286270 TI - Crystal synovitis. PMID- 4286271 TI - Status report on virus isolation in infectious hepatitis (I.H.). PMID- 4286272 TI - Active immunization against infection caused by B virus. (Herpes-virus simiae). II. Dynamics of neutralizing antibodies in rabbits immunized with inactivated vaccine and challenged with live virus. Attempts to obtain highly active antiserum against B virus. PMID- 4286273 TI - Prevention of corrosive stricture of the oesophagus in the rat. PMID- 4286274 TI - Effects of estrogenic hormones on the mammary tissue of agent-free and agent bearing male mice. PMID- 4286275 TI - Growth characteristics and virology of regressing Rous sarcomas. PMID- 4286276 TI - Genetic studies on the etiology and morphology of mammary tumors in mice. PMID- 4286277 TI - Hyperplastic lesions of mouse mammary glands after treatment with 3 methylcholanthrene. PMID- 4286278 TI - Genetic influence of the Rs locus on susceptibility to avian tumor viruses. II. Rous sarcoma virus antibody production after strain RPL12 virus inoculation. PMID- 4286279 TI - Adenovirus and intussusception. PMID- 4286280 TI - [On fatal complications following intravenous injection of organo-iodate contrast media and on the unreliability of the sensitivity tests]. PMID- 4286281 TI - [Hereditary primary hemochromatosis or hemochromatosis secondary to alcoholic cirrhosis? Observation of a case complicated by malignant hepatoma and thrombosis of the portal vein]. PMID- 4286282 TI - [Influence of methandrostenolone on the glucose-6-phosphatase activity of the mouse liver]. PMID- 4286283 TI - Two cases of Sheehan's syndrome. PMID- 4286284 TI - [On the treatment of adenomatosis of the lungs]. PMID- 4286285 TI - Bronchial adenomata. A clinical resume. PMID- 4286286 TI - The relation between structure and function in electron-transport systems. I. Sequential release of nicotinamide-adenine dinucleotide dehydrogenase activity by a series of physical treatments. PMID- 4286287 TI - Cytochrome c oxidase and phosphatides. I. Spectral changes associated with changes in phosphatide profile. PMID- 4286288 TI - [Study of cytochrome oxidase from Pseudomonas aeruginosa]. PMID- 4286289 TI - Intracellular localization and properties of trimethylamine-N-oxide reductase in Vibrio parahaemolyticus. PMID- 4286290 TI - Lipoyl dehydrogenase from Saccharomyces cerevisiae. I. Purification and some properties. PMID- 4286291 TI - Phosphate transfer from adenosine diphosphate phosphoglycerate and 2,3 diphosphoglycerate. PMID- 4286293 TI - Lactate dehydrogenase activity in the preimplanted mouse embryo. PMID- 4286292 TI - The effect of increased pH on the spectral properties of fungal laccase. PMID- 4286294 TI - [Thecoma of the ovary with hyperplasia of the controlateral hilus]. PMID- 4286295 TI - [Apropos of Kruckenberg's tumors in a 14-year-old girl]. PMID- 4286296 TI - [Cytomegalic inclusion disease]. PMID- 4286297 TI - Evidence for the role of bound water and partial desiccation in carcinogenesis. PMID- 4286298 TI - Direct x-ray inactivation of the viruses of Teschen and Talfan diseases, foot-and mouth disease and vesicular stomatitis. PMID- 4286299 TI - Rapid biochemical presumptive test for gonorrheal urethritis in the male. PMID- 4286301 TI - [Value of vaccination against adenoviruses in the Navy]. PMID- 4286300 TI - Formalinized red cells in diagnostic virology. PMID- 4286302 TI - [Can we hope to guard against myxovirus diseases by the use of chemically modified nucleic acids?]. PMID- 4286303 TI - The biochemistry of heme-iron. PMID- 4286304 TI - [Chemistry of biologically active non-heme iron]. PMID- 4286305 TI - The biochemistry of copper. PMID- 4286306 TI - The biological function of molybdenum. PMID- 4286307 TI - Clinical use of diazoxide and mechanism for its hyperglycemic effects. PMID- 4286308 TI - A poliovirus-induced double-stranded RNA: double-helical properties and labelling kinetics. PMID- 4286309 TI - Studies on cytochrome a. XIV. The sulfhydryl groups in cytochrome a. PMID- 4286310 TI - Kinetic studies on the action of collagenase. PMID- 4286311 TI - The localization of succinic dehydrogenase, cytochrome oxidase and adenosine triphosphatase in ciliated respiratory epithelium. PMID- 4286312 TI - The electron-histochemical demonstration of phosphoglyceride. PMID- 4286313 TI - The preferential demonstration of deoxyribonucleic acid by a periodic acid-silver diamine method for light and electron microscopy. PMID- 4286315 TI - Evaluation of an antineoplastic agent. Dactinomycin (Cosmegen). PMID- 4286314 TI - Fluorescent antibody studies of virus-induced tumors. PMID- 4286316 TI - Restless legs syndrome in uremic neuropathy. PMID- 4286317 TI - Aphasia due to a right hemisphere tumor in a right-handed man. PMID- 4286318 TI - Long-term survival following conservative surgery for bilateral arrhenoblastoma. Report of a case. PMID- 4286319 TI - Direct lymphangioadenography of the uterine cervix. PMID- 4286320 TI - Clear-cell adenocarcinoma in an endometrioid ovarian cyst. PMID- 4286321 TI - The effect of corticotropin hormone on lipolytic activity in the adrenal glands of the rat. PMID- 4286322 TI - Increased activities of glycogenolytic enzymes in liver after splanchnic-nerve stimulation. AB - Electrical stimulation of the splanchnic nerve of rabbits caused a marked increase, within 30 seconds after the onset of stimulation, in liver-glycogen phosphorylase and glucose-6-phosphatase activities. The increased activity of liver phosphorylase after splanchnic-nerve stimulation was likewise observed in adrenalectomized and pancreatectomized rabbits. Glycogen content of the liver decreased only slightly after 5-minute stimulation. PMID- 4286323 TI - Virus: mixed infection with herpes simplex and simian virus 40. AB - Mixed infection, the infection of a single cell by two distinguishable viruses, has been demonstrated by electron microscopy in cultures of African green monkey kidney cells after inoculation with simian virus 40 and herpes simplex. Mixed infection occurs rarely when the two viruses are inoculated simultaneously, but if herpes is inoculated 24 hours after SV40 both viruses are found in the same nucleus in about 5 percent of intact cells. PMID- 4286325 TI - [Progressive, sensory neuropathy in 2 children]. PMID- 4286324 TI - The action of physalaemin on the systemic arterial blood pressure of some experimental animals. PMID- 4286326 TI - [Acute dangerous phases and terminal conditions in thyroid gland diseases]. PMID- 4286327 TI - [Terminal conditions in adrenal cortex insufficiency]. PMID- 4286328 TI - [Recognition, dangers and treatment of hypoglycemia]. PMID- 4286329 TI - Complement-fixing antigens in hamster tumors induced by the Bryan strain of Rous sarcoma virus. AB - Hamster tumors transplanted subcutaneously from primary intracranial tumors which developed after inoculation of the Bryan strain of Rous sarcoma virus, contained virusspecific tumor antigens indistinguishable from those induced by the Schmidt Ruppin strain. PMID- 4286330 TI - [On the preventive effect of amantadine hydrochloride in influenza and other respiratory viral infections]. PMID- 4286331 TI - [Study of the viral etiology of respiratory diseases in servicemen. Preliminary report on the Turku garrison]. PMID- 4286332 TI - [The role of the spleen in endocrine activity. 8. Influence of splenic agents on the conjugation of hydrocortisone-4-C14]. PMID- 4286333 TI - Ferredoxin linked DPN reduction by the photosynthetic bacteria Chromatium and Chlorobium. PMID- 4286334 TI - Enlarged chromosome No. 1 in a patient with primary amenorrhoea. PMID- 4286335 TI - Carcinoma and the calcified gall bladder. PMID- 4286336 TI - [Syntheses in the polymyxin series. 11. Synthesis of circulin A]. PMID- 4286337 TI - [Acute pericarditis with reaction of positive complement fixation to adenoviruses]. PMID- 4286338 TI - Viral respiratory diseases in Nigeria: a serological survey. I. Complement fixing antibody levels of influenza A, B and C and para-influenza 1. PMID- 4286339 TI - Triplet ESR in L-tyrosine. PMID- 4286340 TI - [Cylindromatous tumor of the salivary glands with unilateral syndrome of the cranial nerves and multiple visceral metastases]. PMID- 4286341 TI - Osteolytic sterol in human breast cancer. AB - Eleven of twelve human breast cancers contained a lipid which increased urinary (45)Ca and (40)Ca excretion of (45)Ca-labeled, parathyroidectomized rats receiving a low Ca diet. The lipid has mobility on thin-layer chromatography and gas-liquid chromatography close to, but not identical with, that of 7 dehydrocholesterol. Authentic 7-dehydrocholesterol has osteolytic activity similar to that of the extracted sterol. Fluorescence and Lieberman-Burchard reactions of the extracted sterol are similar to those of 7-dehydrocholesterol. The lipid was found by thin-layer chromatography in the extracts which had osteolytic activity. Neither the lipid nor osteolytic activity was found in extracts of tissue from two normal human breasts. PMID- 4286342 TI - Fumarate reductase in the control of heme biosynthesis. AB - A drug-induced stimulation of heme biosynthesis in mouse liver was accompanied by altered fumarate metabolism. In liver homogenate, fumarate 1,4-C(14) was incorporated, via succinate and succinyl coenzyme A, into heme at an accelerated rate. This pathway of fumarate utilization was inhibited by acetoacetate but not by beta-hydroxybutyrate. Fumarate reduction to succinate required reduced nicotinamide adenine dinucleotide. The enzyme fumarate reductase is suggested as a link between terminal oxidation and cellular control of the heme biosynthetic pathway. PMID- 4286343 TI - Interferon: lack of detectable uptake by cells. AB - No interferon, or at most a small fraction of that applied, is taken up by cells during the period of induction of antiviral activity. The lack of detectable adsorption was not influenced either by the concentration of interferon or the volume. The results were similar in both chicken and mouse systems. PMID- 4286344 TI - Oxidative phosphorylation in extracts of thiobacillus X. PMID- 4286345 TI - Incorporation of myoinositol-3H into the phosphoinositides of cat brain in vivo. PMID- 4286346 TI - Substrate specificity and inhibition studies on potato apyrase. PMID- 4286347 TI - Radioprotection of the rat thyroid by different antithyroid compounds. PMID- 4286348 TI - Survival after high-tension electrical burns complicated by acute tubular necrosis. PMID- 4286349 TI - A generalized theory of particulate electron conduction enzymes applied to cytochrome oxidase. A theory of coupled electron and/or ion transport applied to pyruvate carboxylase. PMID- 4286350 TI - Release of enzymes from rat liver mitochondria by freezing. PMID- 4286351 TI - Nucleic acid of murine encephalomyelitis virus. Physical and chemical studies. PMID- 4286352 TI - Spread of pulmonary coccidioidomycosis associated with steroid therapy. Report of a case with a lupus-like reaction to antituberculosis chemotherapy. PMID- 4286353 TI - A study of human papilloma virus DNA. PMID- 4286354 TI - [Vascular reactivity in experimental hypertension responses of hindquarters preparations of rats]. PMID- 4286355 TI - [Changes in the functional activity of the liver after endolymphatic radiotherapy with lipiodol F-I-131]. PMID- 4286356 TI - Apparent potentiation of neuromuscular block by antibiotics. PMID- 4286357 TI - New Jersey "Chicken trial": verdict for science. PMID- 4286358 TI - Biosynthesis and composition of histones in Novikoff hepatoma nuclei and nucleoli. AB - Histones were prepared from isolated nuclei and nucleoli of the Novikoff ascitic hepatoma at several time points after the injection of L-lysine uniformly labeled with C(14) into tumor-bearing rats. Amino acid analysis and starch-gel electrophoresis failed to reveal any differences between the nuclear and nucleolar histones, although both fractions were more acidic in composition than calf thymus histones. However, the nucleolar histones were a metabolically distinct fraction, and their rate of synthesis was approximately twice that of the total nuclear histones. PMID- 4286359 TI - Nicotinamide-adenine dinucleotide in tubercle bacilli exposed to isoniazid. AB - There is a decrease in the content of nicotinamide-adenine dinucleotide of tubercle bacilli grown in the presence of isoniazid. In extracts of tubercle bacilli, the activity of nicotinamide-adenine dinucleotidase is nil or very small; after incubation with the drug the enzyme becomes active. Isoniazid also increases the activity of the enzyme after it is partially activated by heating. There may be a correlation between the capacity of isoniazid to activate the enzyme and the decrease in the dinucleotide content of the tubercle bacilli. PMID- 4286360 TI - [The problem of cellular inclusions of viral nature in certain rheumatic diseases]. PMID- 4286361 TI - [Comparative study of some types of talalgia and calcaneitis]. PMID- 4286362 TI - [Pulmonary hemosiderosis in heart diseases]. PMID- 4286363 TI - [Tophaceous gout complicating congenital cyanogenetic heart disease. Remarkable effects of surgical treatment of Fallot's trilogy on the course of secondary gout]. PMID- 4286364 TI - [Tuberculous peritonitis in adults. (Apropos of 35 cases)]. PMID- 4286365 TI - [Purulent pericarditis (P.P.). Apropos of 23 cases]. PMID- 4286366 TI - [Observations on the formation in mixed cultures of hemotoxins of Cl. perfringens and oedematiens]. PMID- 4286367 TI - Further observations on geographic variation in the antigenic character of West Nile and Japanese B viruses. PMID- 4286368 TI - Clostridium perfringens food poisoning. Report of an outbreak. PMID- 4286369 TI - [Respiratory nasal mucosa in senescence. 2. Histochemical data on some enzyme activities]. PMID- 4286370 TI - [Contribution to so-called "mixed" tumors with nasal sites]. PMID- 4286371 TI - [Congenital malformations related to cytomegalic inclusion disease]. PMID- 4286372 TI - [Ovarian thecoma in infants. (Anatomo-clinical contribution)]. PMID- 4286373 TI - [The white blood picture in adenovirus infections]. PMID- 4286374 TI - The stimulation of pregnenolone synthesis in the large particles from the adrenals of rats administered adrenocorticotropin in vivo. PMID- 4286375 TI - The diagnosis and treatment of glomus tumor. PMID- 4286376 TI - [On a case of hepatoma in a 10-year-old child]. PMID- 4286377 TI - Nature of the cyst of Trichinella spiralis. PMID- 4286378 TI - [Clinico-epidemiological characteristics of adenovirus infections and their relation to the type of the virus]. PMID- 4286379 TI - [Complications in hormonal therapy]. PMID- 4286380 TI - [Para-influenzal encephalitis]. PMID- 4286381 TI - Clinical and serological response to laboratory-acquired human infection by Indiana type vesicular stomatitis virus (VSV). PMID- 4286382 TI - [Studies on the mechanism of action of endoxan]. PMID- 4286383 TI - The estimation of polynucleotide chain length by a chemical method. PMID- 4286384 TI - Studies on the structure of 23-S ribosomal ribonucleic acid from Escherichia coli. PMID- 4286385 TI - [Suppression of ribonuclease activity by pronase]. PMID- 4286386 TI - Periodate oxidation of pseudouridine. PMID- 4286387 TI - [Severe chronic atrophic gastritis simulating limitis plastica. Presentation of a case with the radiological picture of gastric atrophy and malabsorption syndrome]. PMID- 4286388 TI - Experiences in seeking an ethiodol emulsion for lymphography. PMID- 4286389 TI - Two cases of localized hypertrophic neurofibrosis. PMID- 4286390 TI - Factors affecting the amount and composition of the serum seromucoid fraction. PMID- 4286391 TI - Influence of oxygen and cysteine on the radical state of x-irradiated lyophilized liver. PMID- 4286392 TI - Milker's nodule virus infections in Dorset and their similarity to orf. PMID- 4286393 TI - Management of chemodectomas. PMID- 4286394 TI - Aerosol-induced adenoviral illness resembling the naturally occurring illness in military recruits. PMID- 4286395 TI - The effect of acute respiratory infection on pulmonary function in military recruits. PMID- 4286396 TI - Some surface-active agents and their virucidal effect on foot-and-mouth disease virus. AB - Selected cationic and anionic surface-active compounds were tested to determine their virucidal effect on the foot-and-mouth disease virus, type O, strain M11, propagated in primary calf kidney cells. The chemical inactivation of the virus was tested with 0.5, 1.0, 2.0, and 5.0% concentrations of the selected compounds. Virus controls with pH adjusted to cover the expected range of the mixtures of the chemicals and virus were also tested. The absence of virus from the mixtures of chemical and virus after reaction at 28 C for 2 hr was assayed by inoculating suckling mice with the mixtures. One cationic compound, alkyl methyl isoquinilinium chloride, showed considerable antiviral activity due largely to pH effect. The use of the surface-active agents investigated in this study, in the presence of organic material, would not be recommended as virucides. PMID- 4286397 TI - Effects of animal alimentary passage on the heat resistance of Clostridium perfringens. AB - The resistance to heat, as measured by D values and phantom thermal death time curves, was observed to increase for one of three strains of Clostridium perfringens type A subsequent to animal passage. Animal passage was accomplished by the force-feeding of germ-free mice with bacterial suspensions of the organism, followed by the force-feeding of additional gnotobiotic mice with the contaminated feces. For the one strain in which an increase in heat resistance was noted, the result could not be attributed to mouse feces per se, since the presence of sterile germ-free mouse feces in a suspending medium did not protect C. perfringens spores from elevated temperature destruction. PMID- 4286398 TI - The identification of cerebroside sulfate as a component of the inositol phosphatide fraction of ox brain. PMID- 4286399 TI - Preparation of L-beta-ribonucleosides and L-beta-ribonucleotides. PMID- 4286400 TI - The effect of angiotensin on the 131-I sodium o-iodohippurate renogram. PMID- 4286401 TI - Further studies on the determination of renin in rat kidney. PMID- 4286402 TI - Studies on the determination method of urinary homovanillic acid and its clinical application. PMID- 4286403 TI - [Influence of aminopeptidases and carboxypeptidase on the blood pressure effects of angiotensin]. PMID- 4286405 TI - [Sino-auricular block]. PMID- 4286406 TI - [Cardiac resuscitation in poisoning]. PMID- 4286404 TI - [Corticotropin in infantile spasm with hypsarrhythmia]. PMID- 4286407 TI - [Circulatory arrest of asphyxial origin. Value of external cardiac massage]. PMID- 4286408 TI - [Membrane oxygenators]. PMID- 4286409 TI - [Clinical use of attapulgite by rectal route in the treatment of recto-sigmoid diseases]. PMID- 4286410 TI - [Desquamative interstitial pneumonia (Liebow's syndrome) or proliferation of the granular pneumocytes]. PMID- 4286411 TI - Angiotensin II infusion in renal disease with hypertension. PMID- 4286412 TI - [Iconography of some interesting cases from the clinical or histological point of view]. PMID- 4286413 TI - Topical absorption of polypeptides with dimethylsulfoxide. PMID- 4286414 TI - A central vasomotor action of angiotensin in man. PMID- 4286415 TI - Hydrocortisone and/or desiccated thyroid in physiologic dosage. 18. Dexamethasone, plasma corticosteroids, and response to ACTH. PMID- 4286416 TI - Headaches and seizures. PMID- 4286417 TI - In vitro transformation of hamster and human cells with the adeno 7-SV 40 hybrid virus. PMID- 4286418 TI - SV40-adenovirus "hybrid" populations: transfer of SV40 determinants from one type of adenovirus to another. PMID- 4286419 TI - Generation of free radicals from phenazine methosulfate, streptonigrin, and riboflavin in bacterial suspensions. PMID- 4286421 TI - Fine structure of the epithelial cells in mixed tumors of the parotid gland. PMID- 4286420 TI - Multiplicity and familial incidence of carotid body and glomus jugulare tumors. PMID- 4286422 TI - [Contribution to the problem of malignancy of sweat gland tumors]. PMID- 4286423 TI - [Pemphigus and adrenal cortex]. PMID- 4286424 TI - An endonuclease from silkworm---purification and mode of action. PMID- 4286425 TI - Oscillatory oxidations of reduced pyridine nucleotide by peroxidase. PMID- 4286426 TI - Demonstration of a DPNH: alpha-ketoglutarate oxidoreductase activity in embryonic chick liver supernatant fraction. PMID- 4286427 TI - Glycerol diphosphate disaccharide-pentapeptide: a functional group of the lipid intermediate in cell wall glycopeptide synthesis. PMID- 4286428 TI - Molecular transitions in an induced enzyme with enhanced fluorescence. PMID- 4286429 TI - Enhanced fluorescence of 4-epimerase elicited by 5'-uridine nucleotides. PMID- 4286430 TI - Subcellular fractionation of human liver. PMID- 4286431 TI - The activity of immuno-conglutinin in in vitro viral infections. PMID- 4286432 TI - An antiviral substance from Penicillium cyaneo-fulvum Biourge. II. Biological activities against RNA-containing viruses. PMID- 4286433 TI - Some studies on cellular fractions of the adductor muscle of Pecten maximus. PMID- 4286434 TI - The isolation and identification of "volutin" granules from Tetrahymena. PMID- 4286435 TI - [Experience in the study of sewage decontamination from cytopathogenic enteroviruses at sewage treatment installations]. PMID- 4286436 TI - Studies on the metabolism of pregnenolone sulfate. PMID- 4286437 TI - Effects of a bacterial pyrogen on the pituitary-adrenal axis at various times in the 24 hours. PMID- 4286438 TI - Evidence for the presence of glucuronides of cortisone and cortisol in human urine. PMID- 4286439 TI - One-hour intravenous ACTH test. PMID- 4286440 TI - [Action "in vitro" of erythromycin (pantomycin) stearate on monobacterial cultures of Entamoeba histolytica]. PMID- 4286441 TI - [Phosphocalcium metabolism disorders during secondary bone cancers of condensing form of prostatic origin]. PMID- 4286443 TI - [Pulmonary aspergillosis]. PMID- 4286442 TI - [Treatment of severe iron deficiency anemia by a single and massive dose of iron by intravenous perfusion]. PMID- 4286444 TI - [Lysosomes]. PMID- 4286445 TI - [A new method for the diagnosis of parotid tumors]. PMID- 4286446 TI - [Experimental study of tissue reaction to kaolin and kaolin combined with quartz]. PMID- 4286447 TI - Effect of interferon on polymerization of single-stranded and double-stranded mengovirus ribonucleic acid. AB - Gordon, Irving (University of Southern California, Los Angeles), Sara S. Chenault, Douglas Stevenson, and Jean D. Acton. Effect of interferon on polymerization of single-stranded and double-stranded mengovirus ribonucleic acid. J. Bacteriol. 91:1230-1238. 1966.-The effect of interferon on actinomycin resistant mengovirus ribonucleic acid (RNA) replication in L cells was investigated to determine whether defective or partially polymerized RNA products were made and whether synthesis of any specific class of virus RNA was prevented. RNA labeled with uridine-C(14) was extracted in hot and cold phenol and analyzed by zonal sucrose density centrifugation. Both single- and double-stranded infectious RNA peaks were identified. Interferon treatment caused almost complete depression of uridine-C(14) incorporation throughout linear sucrose gradients except in the 4S region, and no infectivity was detectable in any fraction. These inhibitory effects are attributable to the action of interferon, because they were reversed when cultures were treated with actinomycin D simultaneously with interferon. The results, with those of other investigators, indicate that the step at which interferon interrupts virus multiplication is between the events immediately after uncoating and the formation of template "minus" strands; under the conditions of our experiments, no partially polymerized virus RNA products were made. PMID- 4286448 TI - Complement-fixation tests with cell lines derived from Burkitt's lymphoma and acute leukemias. AB - Armstrong, Donald (Children's Hospital of Philadelphia, Philadelphia, Pa.), Gertrude Henle, and Werner Henle. Complement-fixation tests with cell lines derived from Burkitt's lymphoma and acute leukemias. J. Bacteriol. 91:1257-1262. 1966.-Cells of various lines isolated from Burkitt's lymphomas and acute leukemias and disintegrated by freezing and thawing or sonic treatment were found to react in complement-fixation tests with a considerable proportion of human sera. At least 10(7) cells per milliliter were required for antigenic activity. All but one of 13 sera from Burkitt lymphoma patients were positive, with titers ranging from 1:8 to 1:320. About 20% of sera from American children and 60% of sera from adults, regardless of diagnosis, showed titers in a similar range. Sera giving positive tests with one of the neoplastic white cell antigens usually reacted also with many if not all of the others, but rarely with antigens derived from normal peripheral leukocyte cultures and not at all with HeLa or other human nonleukocytic cells. Various observations indicate that the complement-fixation test measures mainly antigens which are different from those detected by immunofluorescence. The nature of the reactions described remains obscure. PMID- 4286449 TI - Colorado tick fever virus in cell culture. II. Physical and chemical properties. AB - Trent, Dennis W. (University of Oklahoma School of Medicine, Oklahoma City), and L. Vernon Scott. Colorado tick fever virus in cell culture. II. Physical and chemical properties. J. Bacteriol. 91:1282-1288. 1966.-Heat-inactivation kinetics for Colorado tick fever (CTF) virus grown in L cells indicated that more than one rate constant was involved for inactivation at each exposure temperature. An Arrhenius plot of the data indicated the inactivation rate constants to be dependent on the absolute temperature. The energy of activation, for thermal inactivation of the virus, was 17,289 calories per mole, with the Q(10) being 2.6. The optimal pH range for maintenance of CTF viral infectivity was determined to be 7.5 to 7.8. The infectivity of CTF virus was stable to freezing and thawing in diluents which contained: 50% calf serum, 20% glucose, 20% glycerol, 10% bovine serum albumin, 20 mm glutamine, and 2% gelatin. CTF virus replication was insensitive to inhibition by 5-fluoro-2'-deoxyuridine and 5-bromo-2' deoxyuridine, whereas herpes simplex virus was markedly inhibited, as reported by others. Actinomycin D inhibited CTF virus replication when cells were pretreated for 24 and 12 hr prior to infection, but not when the inhibitor was added at the time of infection. The nucleic acid of CTF virus appears to be of the ribose type. PMID- 4286450 TI - Effects of cycloheximide and puromycin on synthesis of simian virus 40 T antigen in green monkey kidney cells. AB - Gilden, R. V. (Wistar Institute, Philadelphia, Pa.), and R. I. Carp. Effects of cycloheximide and puromycin on synthesis of simian virus 40 T antigen in green monkey kidney cells. J. Bacteriol. 91:1295-1297. 1966.-Synthesis of the simian virus 40 (SV40) T antigen in primary African green monkey kidney cells was abolished when cycloheximide was added up to 10 hr postinfection. In contrast, puromycin, another inhibitor of protein synthesis, did not suppress antigen production. The basis of this differential effect was the inability of puromycin to inhibit protein synthesis in the cells used. This was shown by the failure of the drug to depress the incorporation of labeled amino acid into protein and also failure to inhibit poliovirus synthesis. The puromycin preparation used was very effective in inhibiting poliovirus synthesis in HeLa cells. Thus, appearance of the SV40 T antigen is dependent on protein synthesis in infected cells. PMID- 4286451 TI - Formation of a functional electron transport system during growth of penicillin induced spheroplasts of Haemophilus parainfluenzae. AB - Wright, Elizabeth A. (University of Kentucky College of Medicine, Lexington), and David C. White. Formation of a functional electron transport system during growth of penicillin-induced spheroplasts of Haemophilus parainfluenzae. J. Bacteriol. 91:1356-1362. 1966.-Penicillin in a lactose medium can be used to cause the formation of spheroplasts in Haemophilus parainfluenzae. The resulting spheroplasts grew under conditions which produced rapid formation of the electron transport system in the normal bacteria. The following elements that are incorporated into a functionally active electron transport system were formed in spheroplasts: formate and l-lactate dehydrogenases, 2-demethyl vitamin K(2), cytochromes b(1) and c(1), and the cytochrome oxidases. The catabolic enzymes aldolase, glyceraldehyde-3-phosphate dehydrogenase, and malic dehydrogenase showed slight increases in activity. These experiments indicated that spheroplasts can form a fully functional electron transport system essentially similar to that formed during normal growth. The various components of the electron transport system were formed at different rates in the growing spheroplasts. PMID- 4286452 TI - Density gradient centrifugation of bacteria and nonspecific bacteriophage in silica sol. PMID- 4286453 TI - Inhibition of intestinal ion translocase enzymes by culture filtrates of Vibrio cholerae. PMID- 4286454 TI - Density of infectious virus and complement-fixing antigens of two rhinovirus strains. AB - Dans, P. E. (National Institute of Allergy and Infectious Diseases, Bethesda, Md.), B. R. Forsyth, and R. M. Chanock. Density of infectious virus and complement-fixing antigens of two rhinovirus strains. J. Bacteriol. 91:1605-1611. 1966.-Two rhinovirus serotypes (echovirus 28 and HGP) and poliovirus type 1 were banded by isopycnic centrifugation in cesium chloride. The rhinovirus virions had a density of 1.41 g/ml, whereas that of poliovirus was 1.34. Since a number of other enteroviruses also have a density of 1.34 g/ml in cesium chloride, a basic difference in density may exist between the rhinovirus and enterovirus subgroups of the picornavirus family. Whether this difference reflects differences in ribonucleic acid content or binding of cesium ions remains to be determined. In tests with echovirus 28 two peaks of CF activity were detected: one in association with the virion (1.41 g/ml), and a larger peak of lower density (1.30 g/ml). With echovirus 28 antiserum, a heterotypically reactive complement-fixing (CF) antigen was detected in the HGP virus suspension at a density less than that of the virion (1.30 g/ml). This antigen corresponded in density to the less dense CF antigen of echovirus 28. PMID- 4286456 TI - Femoral neuropathy in hemophilia. PMID- 4286455 TI - Application of cell fractionation techniques in the study of cells infected with polyoma virus and Newcastle disease virus. AB - Fisher, Harold W. (University of Rhode Island, Kingston), Hidemi Matsumiya, and Masanobu Azuma. Application of cell fractionation techniques in the study of cells infected with polyoma virus and Newcastle disease virus. J. Bacteriol. 91:1645-1651. 1966.-Techniques which permitted rigorous separation of nuclei and cytoplasm were applied to the study of the formation of Newcastle disease virus (NDV) in an established line of Chinese hamster cells and of polyoma virus (PYV) in mouse embryo fibroblasts. The results obtained for hemagglutinin and plaque forming titers during virus growth were in agreement with those obtained by others, using different techniques. These indicated that NDV matures in the cytoplasm, and PYV in the nucleus, of host cells. PMID- 4286457 TI - Artificial heterokaryons of animal cells from different species. PMID- 4286458 TI - Current concepts in the surgical management of cancer of the pancreas and peripancreatic region. PMID- 4286459 TI - Latent period of vesicular stomatitis virus in chick embryo cells. PMID- 4286461 TI - The biology of avian tumor viruses with especial emphasis on forms of virus: cell integration and the neoplastic nature of tumors induced by these agents. PMID- 4286460 TI - Foot and mouth disease virus RNA as an antigenic factor in the complement fixation reaction applied to the examination of human tumors. PMID- 4286462 TI - A comparison of the cytoplasmic antigens of fowl virus tumours. PMID- 4286463 TI - Indirect bacterial hemagglutination, and its application to the study of bacterial antigens and serologic diagnosis. PMID- 4286464 TI - [Virological investigations of sewage and river waters]. PMID- 4286465 TI - [On the mechanism of "permeation" of enzymes through the outer membrane of tumor cells]. PMID- 4286466 TI - [Ultrastructure of transplantable hepatoma in mice of the C3Ha strain. I. Electron microscopic study of hepatoma 22 and 46]. PMID- 4286467 TI - [Comparative cytophotometric study of reactions of normal and tumor cells to the action of various metabolic inhibitors]. PMID- 4286468 TI - [Radioautographic study of the life cycle of cells of solid tumors. G-o phase of cells of hepatoma and mammary gland tumors]. PMID- 4286469 TI - [Reversible changes in the resistance of cells to the lytic action of trypsin]. PMID- 4286470 TI - [Changes in the intensity of strength of adhesion among cells of normal liver- solid hepatoma--ascites hepatoma]. PMID- 4286471 TI - [On the study of specific antigens of hepatoma induced to rats by N nitrosodiethyl-amine]. PMID- 4286472 TI - Malignant cystosarcoma phyllodes with liposarcoma. PMID- 4286474 TI - [Effect of vasoactive substances and hormones on renal hemodynamics--tested with "3-stage clearance"]. PMID- 4286473 TI - [Intermittent treatment of primary chronic polyarthritis]. PMID- 4286475 TI - Dual respiratory infection with parainfluenza and rhinovirus. The pathogenesis of transmitted infection in volunteers. PMID- 4286476 TI - Respiratory virus vaccines. I. Respiratory syncytial and parainfluenza virus vaccines. PMID- 4286477 TI - [Study of KB cells infected by Myxovirus parainfluenzae 2, 3 or by respiratory syncytial virus. I. Relation between viral multiplication and its cellular manifestations]. PMID- 4286478 TI - [Instability of the terminal 3'-hydroxy sequence of transfer RNA in microorganisms. I. Turnover of terminal AMP in Saccharomyces cerevisiae]. PMID- 4286479 TI - [Apropos of 2 cases of ocular and neuromuscular complications seen during prolonged treatment with chloroquine]. PMID- 4286480 TI - Quantitation of the radiographically determined age dependence of bone thickness. PMID- 4286481 TI - Synthesis of an octadecapeptide and its 18-amide analog corresponding to the first eighteen amino acid residues of corticotropin (ACTH), and their biological activities. PMID- 4286482 TI - [The neurosecretory-hypophyseal system in the presence of adrenalectomy and hormonal action]. PMID- 4286483 TI - [The adrenocorticotropic activity of the hypophysis of the human fetus]. PMID- 4286484 TI - [The effect of ACTH and adrenaline on changes in the cholesterol content of the blood in different functional states of the thyroid gland]. PMID- 4286485 TI - [Clinicoroentgenologic experiences with a bile contrast medium for rapid peroral cholecystography]. PMID- 4286486 TI - [Inhibitory capacity of various synthetic corticosteroids on ACTH secretion. Comparative study]. PMID- 4286487 TI - [ACTH-tropic activity of hypothalamic phospholipids: behavior of plasmatic and urinary corticoids]. PMID- 4286488 TI - [Antagonistic activity of some amino acids on guanidine inhibition of in vitro development of the poliovirus]. PMID- 4286489 TI - [Experimental pathogenetic action of E. histolytica. Anatomo-pathological aspects of experimental pulmonary amebiasis]. PMID- 4286490 TI - Carcinoma of the cervix uteri presenting as Paget's disease of the vulva, with a note on the pathogenesis of the latter. PMID- 4286491 TI - Gingival metastasis from a hepatoma. PMID- 4286492 TI - [Cholesterol migrating with some protein fractions in the serum of Wistar rats on a normal diet and on a high-lipid, high-protein diet and subjected to ESH and ACTH injections]. PMID- 4286493 TI - [Cytochrome oxidase activity of rat embryo cells infected with polyoma virus]. PMID- 4286494 TI - Purification and properties of a specific fructose 1,6-diphosphatase from Candida utilis. PMID- 4286496 TI - Mechanism of action of malt beta-glucanases. 8. Structures of products formed during hydrolysis of barley beta-D-glucan by A11-endo-beta-glucanase. PMID- 4286495 TI - Nicotinamide adenine dinucleotide photoreduction with Chromatium and Rhodospirillum rubrum chromatophores. PMID- 4286497 TI - Mechanism of action of malt beta-glucanases. 9. The structure of barley beta-D glucan and the specificity of A11-endo-beta-glucanase. PMID- 4286498 TI - Mechanism of carbohydrase action. XII. L-Sorbose as an acceptor substrate in transfer reactions catalyzed by potato D-enzyme. PMID- 4286499 TI - A role of catalase in S-methyl group oxidation. PMID- 4286500 TI - Membrane-bound trehalase from cecropia silkmoth muscle. PMID- 4286501 TI - A colorimetric procedure for the determination of N-acetylated-3-amino hexoses. PMID- 4286502 TI - Lymphography in melanoma. Correlation of radiology with pathology. PMID- 4286503 TI - [Rapid synacthen test for the evaluation of adrenocortical function]. PMID- 4286504 TI - Hexosamine and sialic acid in mitochondria and microsome from rabbit liver. PMID- 4286505 TI - Studies on erythrocyte glycolysis. I. Determination of the glycolytic intermediates in human erythrocytes. PMID- 4286506 TI - Studies on cytochrome a. XV. Cytochrome oxidase activity of the Okunuki preparation and its activation by heat, alkali and detergent treatments. PMID- 4286507 TI - Hemoproteins in microsomes in liver of tumor-bearing rats. PMID- 4286508 TI - Nerve abscesses in leprosy in Northern India. PMID- 4286509 TI - Neural involvement in leprosy treatment with intra-neural injections of prednisolone. PMID- 4286510 TI - Physiotherapy and foot drop corrections. PMID- 4286511 TI - [Different effect of bromouracildesoxyriboside and iodouracildesoxyriboside irradiation of herpes simplex viruses with ultraviolet light]. PMID- 4286512 TI - [Ascending polyganglioradiculoneuritis in a case of diabetic encephaloneuropathy]. PMID- 4286513 TI - [Metabolic factors in neuronal biomorphogenesis. I. Observations on karyometry and interkaryometry in the central and peripheral nervous systems]. PMID- 4286515 TI - [The optic nerve]. PMID- 4286514 TI - Thoracic inlet tumors. PMID- 4286517 TI - Glioblastoma multiforme of the optic nerve. PMID- 4286516 TI - The examination of eye movements. PMID- 4286518 TI - [2 severe complications of lymphography]. PMID- 4286519 TI - [On a case of a giant tumor of the neck. Treatment with reparative plastic surgery]. PMID- 4286520 TI - [Note on experimental carotid opacification by liposoluble products]. PMID- 4286521 TI - [Prognostic elements of aortic insufficiency collected in 206 patients less than 50-years-old]. PMID- 4286522 TI - [Familial evolutive characteristic of hemolytic disease caused by anti-Rh isoimmunization]. PMID- 4286523 TI - [Chronic pyelonephritis and the vasculo-renal syndrome of pregnancy]. PMID- 4286524 TI - [On a case of associated myasthenia and autonomous toxic thyroid nodule]. PMID- 4286525 TI - [Chromosomes and spontaneous abortions]. PMID- 4286526 TI - Malignant tumors of salivary gland origin: 37-year review of 184 cases. PMID- 4286527 TI - DPNH oscillations in glycolyzing cell free extracts from beef heart. PMID- 4286529 TI - Effect of angiotensin II on active transport of sodium by toad bladder and skin. PMID- 4286528 TI - Effect of 1,3-bis-(2-chloroethyl)-1-nitrosourea on Ehrlich ascites tumor cells. PMID- 4286530 TI - Sterospecificity of hydrolytic enzymes in their reaction with optically active organophosphorus compounds. I. The reaction of cholinesterases and paraoxonase with S-alkyl P-nitrophenyl methylphosphonothiolates. PMID- 4286531 TI - Action of angiotension on myocardial and renal catecholamines in the rabbit. PMID- 4286532 TI - Fate of intravenously injected iodate and periodate. PMID- 4286533 TI - [Nitrate reduction by cell-free extracts from Bacillus cereus]. PMID- 4286534 TI - Proline incorporation into the proline and hydroxyproline of earthworm-cuticle collagen. PMID- 4286535 TI - Comparison of the biological and serological properties of variola and vaccinia viruses. PMID- 4286536 TI - [Intramolecular exchange between heterocycles in coenzymes. II. Alpha nicotinamide-adenine-dinucleotide]. PMID- 4286537 TI - [Studies on optimal conditions of interferon isolation from polyoma virus infected mouse and hamster cell cultures]. PMID- 4286538 TI - [Hemodynamic effects of beta-angiotensin II]. PMID- 4286539 TI - [Adenovirus pneumonia. Symptomatology and clinical aspects]. PMID- 4286540 TI - [Adenovirus pneumonia. Pathological anatomy]. PMID- 4286541 TI - [On laboratory diagnosis of adenovirus infections]. PMID- 4286542 TI - [Polar spongioblastoma infiltrating the bulbus, with multiple leptomeningeal metastases]. PMID- 4286543 TI - Effects of sulphur compounds on the free radicals in amino acids and proteins. PMID- 4286544 TI - [On heteroantigens of hepatocellular tumors in rats]. PMID- 4286545 TI - The regulation of the synthesis and release of ACTH. PMID- 4286546 TI - Spontaneous reactions of 1,3-substituted 1,4-dihydropyridines with acids in water at neutrality. I. Kinetic analysis and mechanism of the reactions of dihydronicotinamide--adenine dinucleotide with orthophosphates. PMID- 4286547 TI - Stereochemical aspects of the substrate specificity of horse liver alcohol dehydrogenase. PMID- 4286548 TI - Optical rotatory dispersion of ribonuclease and ribonuclease--nucleotide complexes. PMID- 4286549 TI - Syntheses of deoxynucleoside 3'-triphosphates. PMID- 4286550 TI - [Effect of ACTH on the restoration of myoneural junctions during reparative regeneration]. PMID- 4286551 TI - [Changes in the antigenic properties of erythrocytes under the effect of some chemical agents]. PMID- 4286552 TI - [Adrenal cortex hormone production in experimental animals and its regulation during ontogenesis]. PMID- 4286553 TI - Recovery of murine leukemia virus prior to development of leukemia: growth curve and dose response. PMID- 4286554 TI - Electron microscopic study of the distribution of the mouse leukemia virus (gross) in organs of mice and rats with virus-induced leukemia. PMID- 4286555 TI - Direct action of a leukemogenic virus on the thymus. PMID- 4286556 TI - Effect of sex hormones on susceptibility to viral transmission of myeloid leukemia in the mouse. PMID- 4286557 TI - Comparative biochemistry of hepatomas. VI. Thymidine incorporation into DNA as a measure of hepatoma growth rate. PMID- 4286559 TI - [Nil nocere. Acute liver atrophy following perchlorate therapy]. PMID- 4286558 TI - [Some cases of Gradenigo-Lannois syndrome]. PMID- 4286560 TI - [Phosphohydrolytic action of frozen human blood platelets]. PMID- 4286561 TI - The reaction of hydrogen atoms with thymine and DNA. PMID- 4286562 TI - On the mechanism of polyoma virus-induced synthesis of cellular DNA. PMID- 4286563 TI - The nucleic acid from avian myeloblastosis virus compared with the RNA from the Bryan strain of Rous sarcoma virus. PMID- 4286564 TI - A lipopolysaccharide inhibitor of a DNA methyl transferase. PMID- 4286565 TI - A spin-labeled hapten. PMID- 4286566 TI - Virologic studies of acute respiratory disease in young adults. IV. Virus isolations during four years of surveillance. PMID- 4286567 TI - [On the effect of ACTH on the level of non-esterified fatty acids in the plasma of healthy human subjects and diabetics]. PMID- 4286568 TI - [The Metopirone test in growth disorders]. PMID- 4286569 TI - [Results of experimental leukosis research in the chicken from the viewpoint of comparative and special pathology]. PMID- 4286570 TI - Amino acid substitutions resulting from suppression of nonsense mutations. II. Glutamine insertion by the Su-2 gene; tyrosine insertion by the Su-3 gene. PMID- 4286571 TI - The binding of RNA polymerase to polyoma and papilloma DNA. PMID- 4286572 TI - [Considerations on a deficit of the common peroneal nerve in fractures of the fibula head]. PMID- 4286573 TI - [On the histogenesis of juvenile angiofibroma of the rhinopharynx]. PMID- 4286574 TI - [Autohistoradiographic investigations of the lymphatic and splenic localization of poliovirus, type 3, attenuated according to Sabin's method and labeled with I 131. (Experimental research)]. PMID- 4286575 TI - [Association of pyridoxine and ACTH in the treatment of infantile myoclonic encephalopathy with hypsarrhythmia]. PMID- 4286576 TI - [Metabolic behavior of sodium after treatment with varying doses of vitamin D 3. Experimental research with radioisotopes]. PMID- 4286578 TI - [Endocrine evaluation and hypophysial reserve in acromegalic patients]. PMID- 4286577 TI - [Action of different doses of vitamin D 3 on the metabolism of potassium. Experimental research]. PMID- 4286579 TI - Asthma, melancholia, and death. I. Psychoanalytic considerations. PMID- 4286580 TI - Asthma, melancholia, and death. II. Psychosomatic considerations. PMID- 4286582 TI - [An attempt at preparing an antiserum to human intestinal phosphatases]. PMID- 4286581 TI - [Muciparous adenocarcinoma of the appendix with mucocele and periappendicular pseudomyxoma]. PMID- 4286583 TI - [Purification and properties of malate dehydrogenase (decarboxylating) from yeast]. PMID- 4286584 TI - [Contribution to the symptomatology of radiation-induced growth disturbances of the spine]. PMID- 4286585 TI - Organ distribution of radioiodinated Clostridium perfringens alpha toxin. PMID- 4286586 TI - [Contribution to the occurrence of congenital foot-and mouth disease in swine]. PMID- 4286587 TI - [Lymphoplasmocytic encephalitis with vasculogenic necroses]. PMID- 4286588 TI - [On the polysaccharide from Flores chamomillae. 6. Studies on the structural clarification, chemical methods I: periodate oxidation]. PMID- 4286589 TI - [Acute leukosis in adults. I. Clinical and hematological study apropos of 140 cases]. PMID- 4286590 TI - [Acute leukemia in adults. II. Prognostic study apropos of 140 cases]. PMID- 4286591 TI - [Acquired lymph node toxoplasmosis in adults. (Analysis of 30 cases and review of the literature]. PMID- 4286592 TI - [Hematologic aspects of cirrhosis]. PMID- 4286593 TI - [Recklinghausen's disease with jejunal localization]. PMID- 4286594 TI - [Quadruple treatment of severe forms of pulmonary tuberculosis]. PMID- 4286595 TI - [On a retroperitoneal neurogenic sarcoma in Recklinghausen's neurofibromatosis]. PMID- 4286596 TI - [Contribution to the treatment of glomus jugulare tumors]. PMID- 4286597 TI - Mixed parotid tumours. PMID- 4286598 TI - [Tumors of the insular pancreas]. PMID- 4286599 TI - [Our experience with therapy of recurrent herpes simplex with a specific vaccine]. PMID- 4286600 TI - Optokinetic nystagmus and occipital lesions. PMID- 4286601 TI - Glomus tumor of the stomach: case report. PMID- 4286602 TI - Measurement of acetaldehydrogenic steroids in urine. PMID- 4286603 TI - The intracellular distribution of the enzymes catalysing the biosynthesis of glycerides in the intestinal mucosa. PMID- 4286604 TI - Incorporation of phosphate into diphosphoinositide by subcellular fractions from liver. PMID- 4286606 TI - Actinomycin inhibition of "soluble" ribonucleic acid synthesis in rat liver. PMID- 4286605 TI - Isolation, purification, and characterization of P1,P3-diguanosine 5' triphosphate from brine shrimp eggs. PMID- 4286607 TI - The participation of ribonuclease in the degradation of Escherichia coli ribosomal ribonucleic acid as revealed by oligonucleotides accumulation in the phorphorus-deficient stage. PMID- 4286608 TI - [Apropos of the possibility of using freon deproteinization and ultracentrifugation for the purification of Rous sarcoma virus]. PMID- 4286609 TI - [Cytological and immunological reaction of the lymphoid organs to intravenous administration of enterovirus antigen]. PMID- 4286610 TI - [On the antigenic differences between tumorous and homologous normal tissues detected by normal tissue antibodies]. PMID- 4286611 TI - Symposium on pituitary tumours. 3. Historical aspects of radiotherapy, present treatment technique and results. PMID- 4286612 TI - Symposium on pituary tumours. 4. Unusual pathological features. PMID- 4286613 TI - Photosensitization of xanthine-containing substances: electron spin resonance studies. PMID- 4286614 TI - Reduction of iodate and periodate by rat tissues in vitro. PMID- 4286615 TI - Inhibitory activity of tannic acid and flavonols on the infectivity of Herpesvirus hominis and Herpesvirus suis. PMID- 4286616 TI - Murine leukemia viruses: antigenic studies by quantitative complement fixation. AB - The murine leukemia viruses of Rauscher and Friend, derived from plasnma of infected Balb/c mice, was purified. Their antigenic relationship was studied by quantitative complement-fixation reactions with the virion antigen and homologous antiserums. The complement-fixation curves observed in cross-reactions indicated close antigenic similarity between these two leukemia viruses. Highly purified viral preparations contained detectable amounts of host antigens. PMID- 4286617 TI - Virus-induced murine leukemia: its inhibition and suppression by serum containing erythropoietin. AB - Mice infected at 2 days of age with a virus that induces reticulum cell sarcoma and myeloerythroleukemia were treated with erythropoietin-containing serum obtained from rabbits that had been treated with acetylphenylhydrazine. A marked inhibition of tumor induction occurred, particularly in females, when treatment was begun early. Delayed treatment resulted in instances of regression of overt neoplasia. PMID- 4286618 TI - Invasion of tumor cells into the bloodstream caused by palpation or biopsy of the tumor. PMID- 4286619 TI - [Morphology of the trophozoites of Entamoeba histolytica. Study by the electron microscope]. PMID- 4286620 TI - [Mixed tumors of the salivary glands]. PMID- 4286621 TI - Pituitary melanocyte-stimulating hormone (MSH) after suckling stimulus. PMID- 4286622 TI - Evidence for ACTH secretion and ACTH suppressibility in hypophysectomized rats with multiple heterotopic pituitaries. PMID- 4286623 TI - Preparation and properties of growth hormone from equine pituitary glands. PMID- 4286624 TI - Sources of error in the bio-assay of ACTH in the rat. PMID- 4286626 TI - Are pathogenic spores a hospital threat? PMID- 4286625 TI - The localisation of succinic dehydrogenase in the muscles of Nereis Virens and Homarus Gammarus. PMID- 4286627 TI - Contaminant viruses in two live virus vaccines produced in chick cells. PMID- 4286628 TI - Distribution of heat-resistant Clostridium welchii in a rural area of Australia. PMID- 4286629 TI - Studies on the mechanism of destruction of lymphoid tissue in murine hepatitis virus (MHV3) infection. I. Selective prevention of lymphoid necrosis by cortisone and puromycin. PMID- 4286630 TI - [On the effect of vasopressors and volume supply on kidney function restricted after blood pressure decrease]. PMID- 4286631 TI - [Use of vasopressors in shock therapy with reference to acid-base equilibrium]. PMID- 4286632 TI - [Changes in cardiac output and hepatic blood flow in normal subjects following infusion of angiotensin II]. PMID- 4286633 TI - [Angiotensin and adrenal medullary activity]. PMID- 4286634 TI - [Study of the action of angiotensin on cardiac output measured in rabbits by the isotope dilution curve technic]. PMID- 4286635 TI - Radiation sensitivity of cells and base composition of DNA: an electron spin resonance study. PMID- 4286636 TI - [On the modifying influence of peptone on the effect of substances acting on smooth muscle organs. Further studies on the problem of the mechanism of peptone shock]. PMID- 4286637 TI - [Sensitivity of herpes simplex virus to 5-iodo-2'-deoxyuridine]. PMID- 4286638 TI - Further investigations of an assay in vitro for prolactin. PMID- 4286639 TI - Pressor activity in extracts of the corpuscles of Stannius from the European eel (Anguilla anguilla L.). PMID- 4286640 TI - Studies on D-glyceraldehyde-3-phosphate dehydrogenase. XXII. D-glyceraldehyde oxidation. PMID- 4286641 TI - The direct effect of carbon tetrachloride on subcellular particles. PMID- 4286642 TI - Application of the microtiter technique to the quantitation of adenovirus serotypes and their antisera. PMID- 4286643 TI - The chemistry of dermal necrosis. PMID- 4286644 TI - Changes in rat liver cells induced by orotic acid feeding. PMID- 4286645 TI - Amyloidosis: origin from fixed periodic acid-Schiff positive reticuloendothelial cells in loco and basic factors in pathogenesis. PMID- 4286646 TI - [Frey's syndrome]. PMID- 4286647 TI - [Acute poisoning by isoniazid. Clinical and biological remarks. Apropos of a case]. PMID- 4286648 TI - [Human infection by Serratia. Apropos of 3 further cases: bacterio-clinical study]. PMID- 4286649 TI - [Study of the plasma pepsinogen during the Vichy cure. Comparison with changes in the hydrochloric secretion of the stomach]. PMID- 4286650 TI - [The bovine tubercle bacillus. Its identification. Relative incidence of its isolation in man]. PMID- 4286651 TI - [A little-known disease: papillary necrosis of the kidney]. PMID- 4286652 TI - [Apropos of a case of rectosigmoid multi-adenomatosis]. PMID- 4286653 TI - [Simplification of intubation of the duodenum and the jejunum by use of methoclopramide]. PMID- 4286654 TI - [The anatomo-clinical forms of tuberculosis according to etiologic factors]. PMID- 4286655 TI - [Pulmonary and pleural tuberculosis]. PMID- 4286656 TI - [Extrapulmonary tuberculosis]. PMID- 4286657 TI - [Fatal tuberculosis and undiagnosed tuberculosis. General conclusions]. PMID- 4286659 TI - [Differential and etiological diagnosis of functional uterine hemorrhages]. PMID- 4286658 TI - [Carcinoid tumor of the cecum. Value of mesenteric arteriography]. PMID- 4286660 TI - The adrenocorticotrophic properties of alpha-melanophore-stimulating hormone. PMID- 4286661 TI - Adrenal secretion after bilateral adrenalectomy for Cushing's syndrome. PMID- 4286662 TI - Studies of infectious bovine rhinotracheitis virus. II. Effect of metabolic inhibitors on virus multiplication. PMID- 4286663 TI - [Study of a line of KB cells chronically infected with para-influenza virus type 3. II. New properties acquired by KB.EA cells]. PMID- 4286664 TI - Studies on the biologic relationship of some murine leukemia viruses. PMID- 4286665 TI - [Development of herpes virus in the experimentally infected cornea. Immunohistological demonstration of early corneal lesions]. PMID- 4286666 TI - [Malignant mixed tumor of the lacrimal gland. (Clinico-surgical and histopathological study)]. PMID- 4286668 TI - [Malignant abdominal tumors in childhood. Incidence and clinical diagnosis]. PMID- 4286667 TI - Inhibition of cellular RNA synthesis by nonreplicating vesicular stomatitis virus. PMID- 4286669 TI - [Critical study of the diagnosis of langerhansian adenoma from 17 clear functional hypoglycemias in adults]. PMID- 4286670 TI - Isolation syndrome in the rat. PMID- 4286671 TI - The biosynthesis of cyclitols. PMID- 4286672 TI - [Experiences in infusion treatment with Viocin]. PMID- 4286673 TI - Effects of carbon dioxide-bicarbonate mixtures on oxidative phosphorylation by cauliflower mitochondria. AB - 1. Carbon dioxide-bicarbonate mixtures markedly inhibited oxidation and phosphorylation rates of mitochondria prepared from cauliflower. Inhibition occurred with succinate, malate, citrate, isocitrate and NADH as substrates. 2. Indophenol-reductase systems with malate, succinate, isocitrate and NADH as substrates were inhibited by 5% and 15% carbon dioxide. Cytochrome c oxidase was not inhibited by 15% carbon dioxide. PMID- 4286675 TI - The molecular structure of bacterial walls. The size of ribitol teichoic acids and the nature of their linkage to glycosaminopeptides. AB - 1. Ribitol teichoic acids prepared by fractional precipitation of trichloroacetic acid extracts of bacterial cell walls are essentially undegraded and have similar chain length to the teichoic acid originally present in the walls. 2. The chain length of teichoic acid can be determined directly, without prior extraction from the wall. Accurate values have been obtained by measurement of the formaldehyde produced by oxidation of walls with periodate. Less accurate values have been derived from the amount of inorganic phosphate formed by heating walls at pH4. 3. The relative amounts of N-acetylglucosaminylribitol and its mono- and di phosphates produced by heating walls of Staphylococcus aureus with alkali agree with the amounts calculated for the hydrolysis of teichoic acid having the chain length determined by other methods. 4. Chemical considerations indicate that the linkage between teichoic acid and the wall may involve a phosphoramidate bond between the terminal phosphate of the teichoic acid and one of the amino groups in the glycosaminopeptide. PMID- 4286674 TI - Studies on the fractionation of mucosal homogenates from the small intestine. AB - 1. Homogenates of the mucosa of the small intestine of the guinea pig were separated by fractional sedimentation into seven different fractions. The enzymic properties of some of these subcellular fractions were compared with those obtained from the mucosa of the small intestine of the rabbit and cat. 2. The enzymic properties of the low-speed sediment (15000g-min.) were investigated and it was shown that invertase and alkaline ribonuclease were predominantly located in this subcellular fraction, whereas alkaline phosphatase, aryl-amidase, acid phosphatase, acid ribonuclease and phosphoprotein phosphatase, though true constituents of this fraction, occurred to varying degrees in other subcellular structures also. 3. It was shown that the most probable source of the enzymic activities observed in the low-speed sediment was the brush border. Electron micrographs of the purified brush-border fraction indicated vesicles derived from the brush-border membrane. 4. A method is described for the fractionation of mucosal homogenates into a brush border-plus-nuclei fraction, a mitochondrial fraction, a microsomal fraction and a particle-free supernatant. The fractions were shown to be relatively pure, as indicated by the distribution of invertase, DNA, succinate dehydrogenase, glucose 6-phosphatase and 6-phosphogluconate dehydrogenase. 5. Most of the activity of four lysosomal enzymes present in the nuclei-free homogenate was sedimented at 375000g-min., suggesting the occurrence of lysosomal particles in mucosal homogenates. 6. Further fractionation of the microsomal membranes into three fractions is described. The enzymic composition of the membrane fractions is given and discussed in relation to their structure as seen in electron micrographs. PMID- 4286676 TI - Electron transport in a Park-Williams strain of Corynebacterium diphtheriae. AB - 1. The electron-transport mechanism was examined in the ;particulate' and ;supernatant' fractions of disintegrated cells of a Park-Williams strain of Corynebacterium diphtheriae. 2. Succinate-oxidase activity was found mainly in the ;particulate' fraction, and NADH(2) oxidase mainly in the ;supernatant', which was devoid of cytochromes and menaquinone. 3. The sum of the activities of particles and supernatant fractions, with respect to both succinate oxidase and NADH(2) oxidase, was substantially less than that of the crude cell extract from which they were obtained. Full activity was restored on recombining ;particles' and ;supernatant'. The characteristics of this reassembled system were investigated. 4. The strain of organism (CN2000) examined contained cytochromes corresponding spectroscopically to ;a', ;b' and ;c' types. All three were reduced by succinate, lactate or NADH(2); but a portion of the cytochrome b, susceptible to reduction by dithionite, could not be reduced by the substrates. 5. Triton X 100 inhibits oxidation of succinate by particulate fraction; on adding succinate, the reduction of cytochrome b is not affected but that of cytochromes a and c is delayed. 6. Irradiation at 360mmu completely destroys menaquinone in the particle fraction. Succinate oxidation is severely decreased; succinate dehydrogenase and NADH(2) oxidation are little affected. Certain menaquinones will restore succinate oxidation in the irradiated material. 7. On adding succinate to irradiated particulate material cytochrome b is partially reduced at once, but reduction of cytochromes a and c is much delayed. A portion of the cytochrome b remains not reduced, but reduction occurs rapidly on the addition of menaquinone (MK-2). PMID- 4286678 TI - Studies concerning the polishing properties of zirconium silicate on enamel. PMID- 4286677 TI - The immunochemistry of Salmonella chemotype VI O-antigens. The structure of oligosaccharides from Salmonella group G (o 13,22) lipopolysaccharides. AB - 1. Lipopolysaccharides have been isolated from ;smooth' (S) strains of Salmonella friedenau and Salmonella poona by the phenol-water method and purified in the preparative ultracentrifuge. 2. These lipopolysaccharides are serologically indistinguishable and on partial acid hydrolysis the same series of oligosaccharides was obtained in each instance. 3. The results of quantitative micro-analysis, borohydride reduction, periodate oxidation, Morgan-Elson reactions and enzymic hydrolysis with beta-galactosidase on the isolated oligosaccharides indicate that the O-specific side chains of these lipopolysaccharides have a repeating pentasaccharide unit that is beta-d galactosyl-(1-->3)-N-acetylgalactosaminyl-(1-->3)-N-acetylgalactosaminyl-(1-->4) l-fucose with a d-glucose residue bound at an undetermined point on this structure. 4. Two oligosaccharides, a glucosyl-galactose and an N acetylglucosaminylglucose, have also been isolated and these seem to be identical with oligosaccharides obtained from ;rough' (R) Salmonella lipopolysaccharides. These findings are in accordance with the view that Salmonella S lipopolysaccharides have a core that consists of R-lipopolysaccharide. PMID- 4286679 TI - Emphysematous gastritis associated with adenocarcinoma of the stomach. PMID- 4286680 TI - [Pulmonary function and anatomical peculiarities in alveolar cell carcinoma (lung adenomatosis)]. PMID- 4286681 TI - Comparative studies on the electrical properties and enzyme activities in skins of Rana catesbeiana. PMID- 4286682 TI - [Renin activity in the plasma in normal, increased and diminished blood pressure]. PMID- 4286683 TI - Studies on Japanese B encephalitis virus vaccines from tissue culture. V. Response of man to live, antenuated strain of OCT-541 virus vaccine. PMID- 4286684 TI - Further studies on acquired resistance to murine cryptococcosis: enhancing effect of Bordetella pertussis. PMID- 4286685 TI - The antigens of vesicular stomatitis virus. I. Separation and immunogenicity of three complement-fixing components. PMID- 4286686 TI - [Clinical studies on the plasma corticosterone in man. I. The role of ACTH on the regulation of corticosterone secretion]. PMID- 4286687 TI - Effects of Polybrene on adrenal cortex. PMID- 4286689 TI - Hoarseness, peripheral neuropathy, and diffuse nodular cutaneous lesions. PMID- 4286688 TI - Pulmonary alveolar proteinosis. A study using enzyme histochemistry, electron microscopy, and surface tension measurement. PMID- 4286690 TI - [Possibilities and limitations in the treatment of salaam convulsions]. PMID- 4286691 TI - [On the etiology and clinical aspects of respiratory tract infections in childhood. I. Virologic studies]. PMID- 4286692 TI - Congenital cerebral granulomas. Report of four cases in male siblings. PMID- 4286694 TI - Quantitative determinations of phosphatase activities in Phallusia mamillata eggs and embryos. PMID- 4286693 TI - [Studies on mechanism of psycho-neurotic disturbances caused by INAH administration. 3. Clinical studies on psycho-neurotic disturbances caused by INAH administration]. PMID- 4286695 TI - Relationship of rehinovirus infection to mild upper respiratory disease. 3. Further epidemiologic observations in military personnel. PMID- 4286696 TI - The Virus Watch program: a continuing surveillance of viral infections in metropolitan New York families. II. Laboratory methods and preliminary report on infections revealed by virus isolation. PMID- 4286697 TI - The Virus Watch program: a continuing surveillance of viral infections in metropolitan New York families. 3. Preliminary report on association of infections with disease. PMID- 4286698 TI - Antigenic studies on Sabin types 1 & 3 poliovaccine virus during 1 to 7 passages in the human intestinal tract. PMID- 4286699 TI - Pleomorphic salivary gland adenoma of the tongue. PMID- 4286700 TI - [Creatine phosphokinase in serums of patients with progressive arthritis]. PMID- 4286701 TI - [Langerhansian adenoma: clinical and biological study]. PMID- 4286702 TI - [Problems which Langerhansian adenomas pose for the surgeon]. PMID- 4286703 TI - The effect of pH on transformation of BHK21 cells by polyoma virus. II. Kinetic considerations. PMID- 4286705 TI - Viral hepatitis with hepatic coma. PMID- 4286704 TI - Rapid cytopathic changes and transformation in human foreskin cell cultures infected with simian virus 40. PMID- 4286706 TI - [Glomangiomatosis (blue rubber bleb naevus?)]. PMID- 4286707 TI - Corticosteroids and corticotrophin in the treatment of Crohn's disease. PMID- 4286708 TI - Electron microscopy of antigen precipitates extracted from gel diffusion plates. PMID- 4286709 TI - Observations on pancreatic islet cell and other radiation-induced tumors in the rat. PMID- 4286710 TI - [Response of total urinary 17-ketosteroids excretion to intramuscular adrenocorticotropin injection in various diseases of children and in cases of long-term treatment with glucocorticoids]. PMID- 4286711 TI - [Mixed tumors of the pharyngeal exclave of the parotid gland]. PMID- 4286713 TI - [Periodate oxidation of methylated mannose derivatives in the course of the study on the structure of mannan in diphtherial bacilli]. PMID- 4286712 TI - [Dynamics of phosphorus compounds in the development of C1. perfringens]. PMID- 4286714 TI - [Isolation and characteristics of purified lecitsinase from Cl. perfringens]. PMID- 4286715 TI - Pulmonary oil deposition in patients subjected to lymphography: Detection by thoracic photoscan and sputum examination. AB - During clinical trials of intralymphatic therapy with radioiodinated ethiodized oil (Lipiodol Ultra-Fluid; Ethiodol) [LUF-I(131)] for malignant disease involving lymph nodes, significant pulmonary deposition of radioactive material was demonstrated by thoracic scan in each of five cases treated. Radioactivity was detected in sputum obtained from two cases. Induced sputum specimens were subsequently obtained from patients undergoing lymphography. Fat demonstrated in sputum was confirmed as Lipiodol in one of six patients tested. Sputum examination and use of tracer doses of LUF-I(131) plus photoscanning are suggested as sensitive methods of assessing the incidence of oil deposition in the lungs of patients undergoing lymphography. Despite limitation of the volume of oil injected, monitoring of the infusion, and absence of radiographic evidence of contrast medium in the lungs, some degree of pulmonary oil deposition appears to be an inevitable result of lymphography. Further study of lung dosimetry is being undertaken by the authors before clinical usage of endolymphatic radioisotope therapy is expanded. PMID- 4286716 TI - A study of the classification of male hypogonadism with observations on the control of 17-oxosteroid precursors from the testes and adrenals. PMID- 4286717 TI - Substituent effects on oxidation and stabilization of phenothiazine semiquinone free radicals. PMID- 4286718 TI - [The effects of various ligands on resorption, distribution and excretion of iron after oral administration]. PMID- 4286719 TI - The treatment tumours of the parotid gland. PMID- 4286720 TI - [Relations between estrogens and adipose tissue. Considerations and findings]. PMID- 4286721 TI - [Validity of cytological examination of nipple secretions in the early diagnosis of mammary carcinoma]. PMID- 4286722 TI - A fluorimetric determination of unconjugated cortisol in human urine after paper chromatography. PMID- 4286723 TI - [Effect of lycorine on the pituitary-adrenal system]. PMID- 4286724 TI - Comparison of effect of environmental and preoptic heating and pyrogen on plasma cortisol. PMID- 4286725 TI - The fine-structural localization of phosphatases in neurosecretory cells within the ganglia of certain gastropod snails. PMID- 4286726 TI - [Excretion of dehydroepiandrosterone in the urine of newborn. Stimulation by chorionic gonadotropins and ACTH]. PMID- 4286727 TI - Paget's disease of the male breast. A case report. PMID- 4286728 TI - Carcinoma of the parotid gland. PMID- 4286729 TI - Glandular tumors of the upper respiratory tract. A clinicopathologic assessment. PMID- 4286730 TI - Primary signet ring cell carcinoma of the urinary bladder. PMID- 4286731 TI - [Contribution to the development of improved embedding materials for the casting of precious metal alloys with special reference to vacuum embedding]. PMID- 4286733 TI - Advantages resulting from the addition of a versatile multichannel analyser to an electron spin resonance spectrometer. PMID- 4286732 TI - Importance of the carboxyl end of bradykinin and other peptides. PMID- 4286734 TI - Serological relationship between adenovirus haemagglutinins of group 2. PMID- 4286735 TI - Treatment of malignant tumors. PMID- 4286736 TI - The use of SV 40-transformed cells for titrations of bovine viral diarrhoea and hog cholera viruses. PMID- 4286737 TI - Hypopituitarism: a study of growth hormone and other endocrine functions. PMID- 4286738 TI - Angiotensin-induced natriuresis in cirrhosis in the absence of endogenous aldosterone secretion. PMID- 4286740 TI - Soluble factors improving the phosphorylative efficiency of yeast mitochondria. PMID- 4286739 TI - The behavior of sterols on silica surfaces and at other interfaces. PMID- 4286741 TI - [Granular cell tumor of the trachea]. PMID- 4286742 TI - [Architectonical study of malignant hepatomas in humans]. PMID- 4286743 TI - Association of adenoviruses with bovine respiratory diseases. PMID- 4286744 TI - Hepatic tumours in ducks fed a low level of toxic groundnut meal. PMID- 4286745 TI - Serum transport of vitamin D. PMID- 4286746 TI - [The pituitary corticotropic hormone. Biochemistry and physiopathology. I]. PMID- 4286747 TI - [Infrared spectroscopy of mineral dust from human lungs]. PMID- 4286748 TI - [Clinical studies on the etiology of essential hypertension. Pressor response to noradrenaline]. PMID- 4286749 TI - [Priapism during hemoglobinosis]. PMID- 4286750 TI - Clinical aspects of primary carcinoma of the liver. PMID- 4286751 TI - Observations of cortical nodules in human adrenal glands. Their relationship to neoplasia. PMID- 4286752 TI - Evaluation of the demonstration of complement-requiring neutralizing antibody as a means for early diagnosis of herpes virus infections. PMID- 4286753 TI - Human cytomegalovirus: properties of the complement-fixing antigen. PMID- 4286754 TI - The in vitro and in vivo effects of cortisol on interferon production and action. PMID- 4286755 TI - [Malignant tumors of the uterus secondary to metastases of cecal carcinoma]. PMID- 4286756 TI - [Apropos of a case of Abrikosov's tumor of the skin]. PMID- 4286757 TI - A glucagon-secreting alpha-cell carcinoma of the pancreas. PMID- 4286758 TI - ESR study of gamma-irradiated polynucleotides. PMID- 4286759 TI - A spin-labeled substrate for alpha-chymotrypsin. PMID- 4286760 TI - Twisted circular DNA: sedimentation coefficients and the number of twists. PMID- 4286761 TI - The effects of nontumor viruses on virus-induced leukemia in mice: reciprocal interference between Sendai virus and Friend leukemia virus in DBA-2 mice. PMID- 4286762 TI - Sustained sinusoidal oscillations of reduced pyridine nucleotide in a cell-free extract of Saccharomyces carlsbergensis. PMID- 4286763 TI - Induction of cellular DNA synthesis by polyoma virus. 3. Induction in productively infected cells. PMID- 4286764 TI - Heterogeneous RNA's occurring during the replication of Western equine encephalomyelitis virus. PMID- 4286765 TI - Evidence for semiconservative replication of circular polyoma DNA. PMID- 4286766 TI - The occurrence of enteroviruses in children from modern flats and squatter dwellings in Singapore. PMID- 4286767 TI - [Electron microscopy studies of the skin of Xenopus laevis in larval and metamorphosis stages following application of potassium perchlorate]. PMID- 4286768 TI - Interference of bovine viral diarrhea virus by hog cholera virus in swine kidney cell cultures. PMID- 4286769 TI - Glycoprotein levels in cattle naturally and experimentally infected with Mycobacterium bovis. PMID- 4286770 TI - Distribution of an antigen in avian leukoses demonstrable by immunofluorescence. PMID- 4286771 TI - Clostridial infections of the abdominal wall: review of 10 cases. PMID- 4286772 TI - Paget's diseases (cancer of the breast): clinical discussion and report of three cases. PMID- 4286773 TI - A, B, and O substances in gastrointestinal carcinoma. PMID- 4286774 TI - Complications of lymphography. PMID- 4286775 TI - Neurologic state of persons exposed to continuous action of sodium dinitrophenolate. PMID- 4286776 TI - Basal adrenocortical function in normal healthy Indians: effect of ACTH stimulation and metyrapone administration, as assessed by urinary steroid excretion. PMID- 4286777 TI - Identification of analogues of nicotinamide adenine dinucleotide among the metabolites of 2,6-diaminopurine in mammalian cells. PMID- 4286778 TI - Mixed function oxidation. V. Flavin interaction with a reduced diphosphopyridine nucleotide dehydrogenase, one of the enzymes participating in camphor lactonization. PMID- 4286779 TI - Nursing students' attitudinal changes following a psychiatric affiliation. PMID- 4286780 TI - Anticipating the effects of program change. PMID- 4286781 TI - Staff development: a responsibility of the employing agency. PMID- 4286782 TI - Staff development: program evaluation. PMID- 4286783 TI - Helping your retarded patients with hearing impairments. PMID- 4286785 TI - They were dressed. PMID- 4286784 TI - The role of the psychiatric aide--a need for reconceptualization. PMID- 4286786 TI - A community mental health service based on principles of family psychiatry. PMID- 4286787 TI - Ward staffing the state mental hospital. PMID- 4286788 TI - Hypoallergenic cosmetics. PMID- 4286789 TI - [Endocrino-metabolic study of ADH-ACTH-cortisol relations in hypophysectomy for hormono-dependant cancers]. PMID- 4286790 TI - On the respiratory spread of varicella-zoster virus. PMID- 4286791 TI - Erythrocyte DPNH dependent diaphorase levels in infants. PMID- 4286792 TI - Urinary excretion of ingestes alpha-aminioisobutyric acid-N-15 in dogs treated with growth hormone or corticotropin. PMID- 4286793 TI - Observations on the release of histaminase after 48/80 and polymyxin B in sensitized and unsensitized rats. PMID- 4286794 TI - Enhanced bacterial virulence in fluids produced in strangulation intestinal obstruction. PMID- 4286795 TI - Multiple virus infection of monkey kidney cells in culture. PMID- 4286796 TI - Fate of poliovirus in northern quahaugs. PMID- 4286797 TI - Serologic relationships of the B632 and ECHO-28 rhinovirus strains. PMID- 4286799 TI - Survival after pulmonary lobectomy for metastatic adrenocortical carcinoma. PMID- 4286798 TI - Experiences with malignant brain tumours in clinic and in tissue culture. PMID- 4286800 TI - [Chorionic villi, vasicular mole and chorioepithelioma: histochemical and microfluoroscopic observations]. PMID- 4286801 TI - [Experimental subcutaneous tumors induced by polyoma virus in rabbits, hamsters and mice]. PMID- 4286802 TI - [Histo-enzymologic research on the parathyroids of albino rats in various ages of life]. PMID- 4286803 TI - Intimal sclerosis in human veins. PMID- 4286804 TI - Effect of adrenocorticotropic hormone on cholesterol level in rat liver in vitro. PMID- 4286805 TI - Effect of promazine on activity of certain liver and blood enzymes in carbon tetrachloride poisoning. PMID- 4286806 TI - Possible mechanisms of appearance and disappearance of free-radical states in cells. PMID- 4286807 TI - Formation of virus particles via enzyme systems and structural proteins induced by another, "assistant" virus. PMID- 4286808 TI - Brain abscess due to gas bacillus infection. Report of a case. PMID- 4286809 TI - [On the problem of cancerogenic effect of inhaled nitrogen oxides]. PMID- 4286810 TI - [Pathogenesis of the hepatorenal syndrome and hemorrhagic enteritis in postabortion septicemia induced by W. perfringens A]. PMID- 4286811 TI - The surgery of the deep lobe of the parotid salivary gland. PMID- 4286812 TI - [Immune reaction in poultry during the development of Rous sarcoma]. PMID- 4286813 TI - [On the problem of the degeneration of gliomas following roentgen irradiation]. PMID- 4286814 TI - [Changes in the turnover rate of phosphorylated fractions and free nucleotides in muscle under the influence of adrenaline]. PMID- 4286815 TI - [Changes in adenine nucleotides and phosphorylated fractions of aortic tissue under the influence of adrenaline]. PMID- 4286816 TI - Useful procedures for the determination of complex fatty acid composition. Occurrence of trans-5-hexadecenoic and trans-5,cis-9-octadecadienoic acids in the oil from Thalictrum venulosum. PMID- 4286817 TI - Appraisal of selective angiography in localizing islet-cell tumors of the pancreas. PMID- 4286818 TI - [Studies on the relation of B. pertussis and parapertussis to tissue cultures. II. Multiplication of B. pertussis and parapertussis in a system containing chick embryo fibroblasts]. PMID- 4286819 TI - Role of the optic ganglia in learning in the crayfish Procambarus clarki (Girard). PMID- 4286820 TI - Hemagglutinating and plaque forming properties of two substrains of simian parainfluenza virus SV5. PMID- 4286821 TI - Studies on the nature of the virus inactivating capacity of sea water. PMID- 4286822 TI - Characteristics of the progeny derived from multiplication of Sendai virus in a measles virus carrier cell line. PMID- 4286823 TI - Effect of Coxsackie viruses of group A and B on Rous sarcoma virus. PMID- 4286824 TI - Enhancement of infectivity of poliovirus RNA with diethylaminoethyl-dextran (DEAE D). PMID- 4286825 TI - Physico-chemical investigation of an enteric cytopathogenic bovine orphan virus, ECBO SA.I. PMID- 4286826 TI - Varicella virus in HeLa cells. PMID- 4286827 TI - Interaction of a simian papovavirus and adenoviruses. I. Induction of adenovirus tumor antigen during abortive infection of simian cells. AB - Feldman, Lawrence A. (Baylor University College of Medicine, Houston, Tex.), Janet S. Butel, and Fred Rapp. Interaction of a simian papovavirus and adenoviruses. I. Induction of adenovirus tumor antigen during abortive infection of simian cells. J. Bacteriol. 91:813-818. 1966.-Adenovirus types 2, 7, and 12 undergo an abortive growth cycle in green monkey kidney cells; they induce the formation of adenovirus tumor antigen, but synthesis of adeno capsid antigen and infectious adenovirus was observed only when cultures were concomitantly infected with a simian papovavirus (SV40). Several other viruses, including herpes simplex and measles which replicate in monkey cells, and rabbit papilloma and human wart papovaviruses which do not, failed to stimulate adenovirus replication in the monkey cells. Adenovirus tumor antigen was detected 8 to 10 hr postinfection by immunofluorescent techniques. The antigen induced by adenovirus types 2 and 7 appeared as intranuclear masses; adenovirus type 12 tumor antigen also appeared as cytoplasmic and nuclear flecks. Sera from hamsters bearing tumors induced by adenovirus type 12 cross-reacted with tumor antigens induced by types 2 and 7 but not with antigens induced by SV40. PMID- 4286828 TI - Assessment of adrenocortical function in the course of viral hepatitis. PMID- 4286829 TI - Studies on transformation of Syrian hamster cells by simian virus 40 (SV40): acquisition of oncogenicity by virus-exposed cells apparently unassociated with the viral genome. PMID- 4286830 TI - Possible incorporation of SV40 genome within capsid proteins of adenovirus 4. PMID- 4286831 TI - Increase of malignant potential of BHK-21 cells by SV40 DNA without persistent new antigen. PMID- 4286832 TI - Specific degradation of the collagen molecule by tadpole collagenolytic enzyme. PMID- 4286833 TI - The synthesis of alpha-ketoglutarate from succinate and carbon dioxide by a subcellular preparation of a photosynthetic bacterium. PMID- 4286835 TI - [Alcoholic disintoxication. Modalities and results of the method used (apropos of 1,000 disintoxications)]. PMID- 4286834 TI - Characterization of ribonuclease-resistant RNA from poliovirus-infected HeLa cells. PMID- 4286836 TI - [Cardiovascular manifestations during conditioning tests in alcoholic disintoxication]. PMID- 4286837 TI - [Study of blood sugar changes in alcoholics]. PMID- 4286838 TI - [Pulmonary histoplasmosis]. PMID- 4286839 TI - [The rheumatologist and antivitamins K]. PMID- 4286840 TI - [Value of the isotope nephrogram in the exploration of arterial hypertension]. PMID- 4286841 TI - Sulphydryl "nothing dehydrogenase" activity and lactic dehydrogenase-NADH2 cytochrome C reductase reactions in tissues of the human foetus. PMID- 4286842 TI - [Histochemical changes in kidney, liver, and spleen with diphtheria toxin poisoning]. PMID- 4286843 TI - A rapid kinetic method for determination of serum alpha-hydroxybutyrate dehydrogenase. PMID- 4286844 TI - Studies on the metabolism of carbon monoxide. PMID- 4286845 TI - Double cancer of the stomach: report of two cases. PMID- 4286846 TI - [A contribution to the formulation of formalin inactivation of poliomyelitis viruses]. PMID- 4286848 TI - [On malignant synovialomas]. PMID- 4286847 TI - Genetic factors in resistance against virus infections. PMID- 4286849 TI - [Study of lactulose oxidation by periodic acid]. PMID- 4286850 TI - [On some beta-D (mannosido)n (1-4) mannitols]. PMID- 4286851 TI - [Structure of a tetrasaccharide isolated from the walls of Micrococcus lysodeikticus]. PMID- 4286852 TI - [Action of angiotensin on the plasma cortisol]. PMID- 4286854 TI - [Apropos of 3 cases of Langerhansian adenoma]. PMID- 4286853 TI - [Behavior of urinary aldosterone and electrolytes during infusion of angiotensin II in normal, essential and renovascular hypertensive subjects]. PMID- 4286855 TI - [Procedure to follow when, during surgery, the surgeon does not find a Langerhansian adenoma]. PMID- 4286856 TI - [Treatment of endogenic hepatic coma by coenzyme A, alpha-lipoic acid, diphosphopyridine nucleotide and cocarboxylase]. PMID- 4286857 TI - Synthesis and transport of protein components of Sendai Virus. PMID- 4286858 TI - [Mouse disease due to vesicular stomatitis virus. I. Spread of the virus dependent on the age of the mouse]. PMID- 4286859 TI - [Mouse disease due to vesicular stomatitis virus. II. Pathology of organ lesions and the involvement of the central and peripheral nervous systems]. PMID- 4286860 TI - Thermal inactivation of 32P-poliovirus at 37 degrees C and 50 degrees C in the presence of NaCl with high molarity. PMID- 4286861 TI - Density gradient centrifugation studies of vesicular stomatitis virus. PMID- 4286862 TI - Mouse macrophages as host cells for murine viruses. (Brief report). PMID- 4286865 TI - Polyribosomes in rat tissues. IV. On the abnormal dimer peak in hepatomas. PMID- 4286866 TI - Replication of gross leukemia virus in long-term cultures of rat thymomas: bioassays and electron microscopy. PMID- 4286867 TI - The effects of fluorocarbon on preparations of a leukemia virus (Gross). PMID- 4286868 TI - Immunology of spontaneous mammary carcinomas in mice IV. Association of the mammary tumor virus with the immunogenicity of C3H nodules and tumors. PMID- 4286869 TI - Some effects of tumor implantation site on tumor-host relations. PMID- 4286870 TI - The fine structure of the Yaba monkey tumor poxvirus. PMID- 4286871 TI - Free radical concentration in irradiated bacterial spores and vegetative cells as measured by the ESR method. PMID- 4286872 TI - Production of free radicals in solid biological substances by heavy ions. PMID- 4286874 TI - [Inositolphosphatides of the rat brain during postnatal growth]. PMID- 4286873 TI - Effect of the irradiation temperature on the production of free radicals in solid biological compounds exposed to various ionizing radiations. PMID- 4286875 TI - [Microdetermination of trypsin by its esterase activity on benzoyl-arginine ethyl ester]. PMID- 4286876 TI - [Demonstration of phosphatidylinositol diphosphate in the proteolipids of the rat brain]. PMID- 4286877 TI - Influence of bacille Calmette-Guerin infection on polyoma in hamsters and mice. PMID- 4286878 TI - Enzymes of nucleic acid metabolism in cells infected with polyoma virus. PMID- 4286879 TI - Tumors in the rat after injection of neoplastic and preneoplastic nucleic acids. PMID- 4286881 TI - Nucleoside kinase activities in tissues infected with Rous sarcoma virus. PMID- 4286880 TI - The activity of streptonigrin against the Rauscher murine leukemia virus in vivo. PMID- 4286883 TI - [Neurological syndromes in cervical osteochondrosis]. PMID- 4286882 TI - [Sialoadenotropic cylindromatous blastomas. (Considerations apropos of 2 cases with an intramaxillary localization)]. PMID- 4286884 TI - Action of streptolysin S, the group D hemolysin, and phospholipase C on whole cells and spheroplasts. AB - Davie, Joseph M. (Indiana University, Bloomington), and Thomas D. Brock. Action of streptolysin S, the group D hemolysin, and phospholipase C on whole cells and spheroplasts. J. Bacteriol. 91:595-600. 1966.-The effect of streptolysin S, the group D hemolysin, and phospholipase C (the alpha toxin of Clostridium perfringens) on whole cells and spheroplasts or protoplasts of three strains of streptococci and Micrococcus lysodeikticus was tested. Viability, C(14)-glycine uptake, and lysis were measured. The group D hemolysin and phospholipase C were active against whole bacteria; streptolysin S was not. All three substances were active on spheroplasts. A partially resistant mutant derived from a strain sensitive to the group D hemolysin was also partially resistant to streptolysin S and phospholipase C. Antimycin A protected spheroplasts from streptolysin S but not from the group D hemolysin. PMID- 4286885 TI - Nitrate reductase and respiratory adaptation in Bacillus stearothermophilus. AB - Downey, R. J. (University of Notre Dame, Notre Dame, Ind.). Nitrate reductase and respiratory adaptation in Bacillus stearothermophilus. J. Bacteriol. 91:634-641. 1966.-Bacillus stearothermophilus 2184 required nitrate to grow in the absence of oxygen. Like many facultative microorganisms, the growth obtained anaerobically was considerably less than that obtained aerobically, even though the dissimilatory reduction of nitrate is, in effect, anaerobic respiration. The ability to reduce nitrate depended on the induction of nitrate reductase. Although oxygen at low levels did not retard induction of the enzyme, enzyme synthesis was considerably lessened by aeration. A semisynthetic medium containing nitrate supported aerobic growth of the thermophile but did not support anaerobic growth. The adaptation to nitrate resulted in a decrease in the level of cytochrome oxidase normally present in aerobically grown cells. Although the aerobic oxidation of succinate by the respiratory enzymes from aerobically grown cells was inhibited by 2-N-heptyl-4-hydroxyquinoline-N-oxide, the anaerobic oxidation of succinate by nitrate in a similar preparation from nitrate-adapted cells was not. The nitrate reductase in the bacillus was strongly inhibited by cyanide and azide but not by carbon monoxide. The nitrate reductase catalyzed the anaerobic oxidation of reduced nicotinamide adenine dinucleotide, and appeared to transfer electrons from cytochrome b(1) to nitrate. Cytochrome c(1) did not appear to be involved in the transfer. PMID- 4286886 TI - Development of antigens in human cells infected with Simian virus 40. AB - Bissett, Marjorie L. (University of Michigan, Ann Arbor), and Francis E. Payne. Development of antigens in human cells infected with simian virus 40. J. Bacteriol. 91:743-749. 1966.-An explanation for the apparent infrequency with which human cells transform in response to exposure to simian virus 40 (SV40) was sought by following the development of virus-induced antigens in human euploid cells, strain CR. For about 8 weeks after exposure to a high multiplicity of SV40, only a small proportion of the cells produced tumor (T) or viral (V) antigen detected by immunofluorescence. Double-tracer staining techniques revealed that the development of T and V antigen in about 1% of the CR cells resembled that in green monkey kidney cells, strain BS-C-1, in which SV40 replicates and destroys all the cells. T antigen was detected before V antigen; both antigens were detected in the nucleus, but only V antigen appeared later in the cytoplasm. All intact cells that contained V antigen also contained T antigen. Infected CR cell cultures, before and after transformation or when in "crisis," contained only 0.1 to 1.0% of cells with both V and T antigen. Some CR cells contained only T antigen, and by 8 days after exposure to virus these cells were present as loose foci associated with an occasional cell containing V antigen. The proportion of CR cells with only T antigen increased from about 1% during the first 4 weeks to 8% at 7 weeks, and to nearly 100% at 11 weeks, when essentially all of the cells were epithelioid. Foci of epithelioid cells were first recognized in the 9th week. It was concluded that those CR cells that contained T antigen at any given time represented (i) a few cells that subsequently produced V antigen and lysed, and (ii) a progressively increasing population that produced only T antigen. If the latter population, in whole or in part, gave rise to the epithelioid transformed cells, then its initial size could account, at least in part, for the apparent infrequency with which human cells transform in response to SV40. PMID- 4286888 TI - [A microspectrophotometric method for the measurement of phosphatase activity in situ in plant tissue with the help of quantitative histochemistry]. PMID- 4286889 TI - Biophysical studies of vesicular stomatitis virus. AB - McCombs, Robert M. (Baylor University College of Medicine, Houston, Tex.), Matilda Benyesh-Melnick, and Jean P. Brunschwig. Biophysical studies of vesicular stomatitis virus: J. Bacteriol. 91:803-812. 1966.-The infectivity and morphology of vesicular stomatitis virus (VSV) were studied after density gradient centrifugation in cesium chloride (CsCI), potassium tartrate (KT), and sucrose. Centrifugation in CsCl revealed two equally infectious bands corresponding to densities of 1.19 and 1.22 g/ml, and a third (density, 1.26 g/ml) band of low infectivity. Two bands (densities of 1.16 and 1.18 g/ml) were observed in the KT gradient, in which the lighter band contained most of the infectivity. Centrifugation in sucrose resulted in a single broad infectious band (density, 1.16 g/ml). The typical rod-shaped VSV particles were found mainly in the lighter bands obtained in CsCl (1.19 g/ml) and KT (1.16 g/ml) and in the single sucrose gradient band (1.16 g/ml). Bent particles equally as infectious as the rod-shaped particles were a constant finding in the CsCl preparations, and were observed mainly in the second band (density, 1.19 g). Numerous strands 15mmu wide were found in the third CsCl (density, 1.26 g/ml) and the second KT (1.18 g/ml) bands. Similar strands could be liberated from VSV particles after treatment with deoxycholate. Internal transverse striations were found to be a regular feature of VSV particles examined with the pseudoreplication negative-staining technique. For crude virus stocks, the physical particle-to-infectivity ratio ranged from 73 to 194. Several morphological similarities between VSV and myxoviruses were observed, including 10 mmu surface projections, pleomorphic morphological forms, and 15 mmu seemingly nucleoprotein strands. PMID- 4286890 TI - [Preliminary results with eosinophils in bilharziasis patients treated with Ciba 32644-Ba]. PMID- 4286887 TI - Hydrolytic enzymes in KB cells infected with poliovirus and herpes simplex virus. AB - Flanagan, John F. (Duke University School of Medicine, Durham. N.C.). Hydrolytic enzymes in KB cells infected with poliovirus and herpes simplex virus. J. Bacteriol. 91:789-797. 1966.-The effect of poliovirus and herpes simplex virus infection on the activity of five hydrolytic enzymes was studied in tissue culture cells of KB type. During the course of poliovirus infection, the activity of beta-glucuronidase, acid protease, acid ribonuclease, acid deoxyribonuclease, and acid phosphatase in the cytoplasm rose to levels two- to fourfold greater than the activity present in the cytoplasm of uninfected cells. The rise in cytoplasmic activity was accompanied by a concomitant decrease in enzymatic activity bound to cell particles. Shift of enzymatic activity from the particulate to soluble state was first detected at 6 hr after poliovirus infection, coinciding with the appearance of new infectious particles and virus cytopathic effect. No net synthesis of these enzymes after poliovirus infection was found. Hydrocortisone added to the culture medium failed to affect either the titer of virus produced in the cells or the release of hydrolytic enzymes from the particulate state. Herpes simplex infection produced minimal alterations in the state of these enzymes in KB cells. It is hypothesized that the breakdown of lysosomes and release of hydrolytic enzymes accompanying poliovirus infection is produced by alterations in cell membrane permeability during the course of virus replication and by the consequent change in the ionic content of the cell sap. PMID- 4286891 TI - Renal arterial hypertension. Incidence, diagnosis and treatment. PMID- 4286892 TI - Pathophysiology and biochemistry of end-stage hypertensive heart disease. PMID- 4286893 TI - Histochemical study of the olfactory bulb in the rodent. PMID- 4286894 TI - Rhinoviruses and common colds. PMID- 4286895 TI - [Phosphoprotein phosphatases in the embryonal appendages of Gallus domesticus]. PMID- 4286896 TI - Some observations on the activity of oxidative enzymes in Poxvirus variolae infected FL and L cell cultures. PMID- 4286897 TI - [Studies on glycoproteins. X. Study of the structure of oligosaccharides isolated from partial hydrolysates of ovomucoid]. PMID- 4286898 TI - The nature and classification of ovarian neoplasms. AB - The classification of ovarian neoplasms on a histogenetic basis according to presentday concepts of development and structure of the ovary is considered. There are four histogenetic categories of primary ovarian tumours: neoplasms of germ cell origin, neoplasms of celomic (germinal) epithelium and its derivatives, neoplasms of specialized gonadal stroma (sex cords and mesenchyme), and neoplasms of non-specialized gonadal stromal and heterotopic elements. In patients of all ages, 70% of ovarian neoplasms were of celomic epithelial origin, 16% of germ cell origin, 5% of specialized gonadal stromal origin, and 9% arose from the non specialized stroma and heterotopic elements. Before 20 years of age, 59% of ovarian neoplasms were of germ cell origin and before puberty they accounted for 90% of all ovarian tumours. The different structural types of neoplasms within the four categories are described. Accurate classification of ovarian neoplasms on a histogenetic basis is stressed if proper treatment is to be given and intelligent assessment of end results is to be made. PMID- 4286900 TI - [Amino acid requirement by various pathogenic microbes]. PMID- 4286901 TI - Feedback effect of corticosteroids at the adrenal level. PMID- 4286899 TI - Formation of 4-methyl-3-pentenoic acid from cholesta-5, 24-dien-3-beta-ol by adrenal enzyme. PMID- 4286902 TI - Studies on the transformation of bovine cells in vitro by SV40, and the properties of the transformed cells. PMID- 4286904 TI - The effect of mercurials on the integrity of the poliovirion. PMID- 4286903 TI - Effect of inhibitors on induction of SV40 tumor antigen by an adenovirus-SV40 hybrid. PMID- 4286905 TI - [Immunizing action on monkeys of normal and guanidine-dependent Sabin poliovirus]. PMID- 4286906 TI - Electrical and mechanical responses of vascular smooth muscle to vasodilator agents and vasoactive polypeptides. PMID- 4286907 TI - Reflex inhibition of sympathetic vasoconstrictor activity at a peripheral locus. PMID- 4286908 TI - [The use of beta-angiotensin II in therapy of shock due to metrorrhagia from abortion]. PMID- 4286909 TI - [The effect of estrogens on the 17-beta-hydroxysteroid: NAD oxidoreductase of rabbit myometrium]. PMID- 4286910 TI - [Does the physiology of the vagina tolerate a virus infection?]. PMID- 4286911 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. VII. Oxidative phosphorylation in the diphosphopyridine nucleotide-cytochrome b segment of the respiratory chain: assay and properties in submitochondrial particles. PMID- 4286912 TI - Biophysical study of the mode of action of the tetracycline antibiotics. Inhibition of metalloflavoenzyme NADH cytochrome oxidoreductase. PMID- 4286913 TI - Growth stimulating activities of vitamin-dependent enzymes in fresh liver for rainbow trout fingerlings. PMID- 4286914 TI - Glyoxylate reductase activity of lactate dehydrogenase. PMID- 4286915 TI - [Changes in the MMD and the LD 50 of the "Col. Sk. poliomyelitis (New Haven)" virus in the mouse as a function of length of time in refrigeration of the brains of the animals inoculated with said virus]. PMID- 4286916 TI - Detection of cells from extramammary Paget's disease of the vulva in a vaginal smear. Report of a case. PMID- 4286917 TI - [Traumatic shock and fat embolism]. PMID- 4286918 TI - [New knowledge on the behavior of enzymes in the callus during fracture healing]. PMID- 4286919 TI - [Experiences with partial liver resection for malignant and benign tumors of the liver]. PMID- 4286920 TI - Complications following lymphography with particular reference to pulmonary oil embolization. PMID- 4286922 TI - Effect of caffeic acid on mouse and ferret lung infected with influenza A virus. PMID- 4286923 TI - Effect of iododeoxyuridine on encephalomyocarditis virus. PMID- 4286921 TI - Live and killed adenovirus vaccines for the prevention of acute respiratory disease in recruits. PMID- 4286924 TI - Nature of the antiviral activity of statolon. PMID- 4286925 TI - Distamycin A, a new antiviral antibiotic. PMID- 4286927 TI - Properties of a virus variant derived from drug-treated mice infected with A-PR8 influenza virus. PMID- 4286926 TI - Antiviral activity of distamycin A. PMID- 4286928 TI - Effect of adrenocorticotropin on the concentration of triglyceride in the adrenal gland of the hypophysectomized rat. PMID- 4286929 TI - Influence of ACTH, food restriction and electric shock on total vitamin A in the rat adrenal gland and on its quantitative histological distribution. PMID- 4286930 TI - Effects of various growth hormone preparations on dog adrenal cortical secretion. PMID- 4286932 TI - Distribution patterns of oxidative enzymes in experimentally induced tumors, regeneration and inflammation of mouse skin. PMID- 4286931 TI - The determination by quantitative histochemistry of the effect of phenothiazines on brain cytochrome C oxidase activity. PMID- 4286933 TI - Relationships among visceral lymphomatosis, bursa of Fabricius, and bursa dependent lymphoid tissue of the chicken. PMID- 4286934 TI - Susceptibility and resistance to viral leukemogenesis in the mouse. 3. Effect of added thymus tissue from a susceptible strain upon the response of two resistant strains. PMID- 4286935 TI - Variation of antigenic characteristics between different mouse lymphomas induced by the Moloney virus. PMID- 4286936 TI - Loss of transplantation antigen in primary simian virus 40-induced tumors and their metastases. PMID- 4286937 TI - Role of the milk agent in disappearance of mammary cancer in C3H/StWi mice. PMID- 4286938 TI - Papovavirus SV40 transplantation immunity conferred by an adenovirus-SV40 hybrid. PMID- 4286939 TI - Effects of partial hepatectomy of rats on the metabolism of formate-C 14 in vivo by host liver and Morris hepatoma 5123-C. PMID- 4286940 TI - Susceptibility of mammary tissues of "genetically resistant" strains of mice to mammary tumor virus. PMID- 4286941 TI - Comparison of the immediate effects of 4 vasopressors on renl blood flow. PMID- 4286942 TI - [Changes in corticl responses to somatosensory stimuli in chronic alcoholic subjects without clinical signs of peripheral neuropathy]. PMID- 4286944 TI - Leukemia in man and mouse. PMID- 4286943 TI - [Metabolic organization of the normal and degenerating peripheral nerve]. PMID- 4286945 TI - Species specificity in reaction between renin and angiotensinogen. PMID- 4286946 TI - Direct action of adrenocorticotrophic hormone on lipase in the adrenal gland of the rat. PMID- 4286947 TI - Growth of foot and mouth disease virus in organ cultures of mouse pancreas. PMID- 4286948 TI - Non-heritable interferon resistance in a fraction of virus populations. PMID- 4286949 TI - Studies of relationship between mouse cytomegalovirus and interferon. PMID- 4286950 TI - Viral spectrum of an established chimpanzee liver cell line. PMID- 4286951 TI - Plaque assay for mouse hepatitis virus (MHV-2) on primary macrophage cell cultures. PMID- 4286952 TI - Effect of vitamin D deficiency on the crystal chemistry of bone mineral. PMID- 4286953 TI - Antigenic relationship of the human and bovine parainfluenza 3 viruses using the Ouchterlony technique. PMID- 4286954 TI - [Study of CS 1530 in ear diseases]. PMID- 4286955 TI - Effects of combined hormone therapy on erythropoiesis in the intact rabbit. PMID- 4286956 TI - Luteoma of pregnancy. PMID- 4286957 TI - Luteomas of pregnancy. PMID- 4286958 TI - Spontaneous and voluntary electrical activity in neuromuscular disorders. PMID- 4286959 TI - Isolation of variant strains from foot-and-mouth disease virus propagated in cell cultures containing antiviral sera. PMID- 4286960 TI - Injuries of peripheral nerves--principles of treatment. PMID- 4286961 TI - Intrathoracic carotid-body tumour (chemodectoma). PMID- 4286962 TI - Angiotensin infusion test in hypertension. PMID- 4286963 TI - [Study in the rabbit of variations of the cardiac flow measured by the isotope dilution curve technic under the action of angiotensin]. PMID- 4286964 TI - [Malignant transformation of human embryo diploid cells under the influence of chicken Rous sarcoma virus]. PMID- 4286965 TI - [Problems posed by the conversion of normal mammalian cells into malignant cells under the influence of chicken Rous sarcoma virus]. PMID- 4286966 TI - [Study of the cytostatic action of an alpha-glyceryl-ether on T 8 carcinoma in rats]. PMID- 4286967 TI - [Aseptic meningitis and similar disease outbreak in the Aomeri area in 1962 and 1963; clinical, epidemiological and virological studies]. PMID- 4286968 TI - [Corticotropin reserve in undernourished patients. II. Evaluation by levels in plasma and urine]. PMID- 4286969 TI - Bilateral synchronous spike wave electrographic patterns in the cat. Interaction of bilateral cortical foci in the intact, the bilateral cortical-callosal, and adiencephalic preparation. PMID- 4286970 TI - Myoblastoma of the tongue. PMID- 4286971 TI - Cytochrome oxidase in latent iron deficiency (sideropenia). PMID- 4286972 TI - [The major syndromes of impairment of movement]. PMID- 4286973 TI - Acidophil adenoma of the pituitary gland and other neoplasms in a boxer. PMID- 4286974 TI - Eccrine spiradenoma. Histochemical and electron microscopic studies. PMID- 4286975 TI - The Atascadero story. PMID- 4286976 TI - Absentee patients; a controlled study of missed appointments in a psychiatric clinic. PMID- 4286977 TI - An experience with the use of group work methods and process with student nurse groups over a period of 5 years. PMID- 4286978 TI - Unconscious motivation in medication errors. PMID- 4286980 TI - International trends. PMID- 4286979 TI - Dusk to dawn. PMID- 4286981 TI - Speaking out. PMID- 4286983 TI - Geriatrics. PMID- 4286982 TI - Are drugs safe? PMID- 4286984 TI - Changes of the sella turcica in chromophobic adenomas and eosinophilic adenomas. PMID- 4286985 TI - [Viral growth and interferon production in mice on a starvation diet infected by Mengo virus]. PMID- 4286986 TI - Transtympanic approach to extratympanic (jugular bulb) chemodectoma. PMID- 4286987 TI - The role of the reticuloendothelial system (RES) on blood lipid alterations and atherogenesis in cholesterol-oil fed and estrogen treated cockerels. PMID- 4286988 TI - Micro-NMR in high permanent magnetic fields. Theoretical and experimental investigations with an application to the secretions from single glandular units in the human uterine cervix. PMID- 4286989 TI - [Recent findings on the chemistry of polymyxins]. PMID- 4286990 TI - The effect of a synthetic beta-1-24-eikosatetrapeptide corticotropin (30'920-Ba Ciba) on plasma corticoids and the urinary 17-KS and 17-OHCS. PMID- 4286991 TI - Precipitating antibody response to herpes simplex virus in rabbits after herpetic keratoconjunctivitis. PMID- 4286992 TI - Cytomegalovirus infection and cytomegalic inclusion disease in renal homotransplant recipients. PMID- 4286993 TI - Cirrhosis and hepatoma in a child. PMID- 4286994 TI - [RNA synthesis in polioviruses. Effect of guanidine]. PMID- 4286995 TI - The effect of adenosine triphosphate, inorganic pyrophosphate and inorganic tripolyphosphate on the stability of cod myosin. PMID- 4286997 TI - Effects of calcium omission on acetylcholine-stimulated amylase secretion and phospholipid synthesis in pigeon pancreas slices. PMID- 4286998 TI - A model for the purification of viruses for the production of specific immune serum. PMID- 4286996 TI - The redox state of NAD+-NADH systems in rat liver during ketosis, and the so called "triosephosphate block". PMID- 4286999 TI - Adenosine 3',5'-phosphate and oscillations of DPNH in a cell-free extract of Saccharomyces carlsbergensis. PMID- 4287000 TI - On the participation of neuraminidase-sensitive sialic acid in the K+-dependent phosphohydrolysis of p-nitrophenyl phosphate by isolated rat-liver plasma membranes. PMID- 4287001 TI - [An epidemic of pharyngo-conjunctival fever due to the adenovirus type 3]. PMID- 4287002 TI - [Antiviral activity of IDU against herpes simplex virus]. PMID- 4287003 TI - [Viral and nuclear DNA syntheses in viral keratitis]. PMID- 4287004 TI - The homolog of the pituitary-adrenocortical axis in the teleost fish Tilapia mossambica. PMID- 4287005 TI - Enterovirus hemagglutination: inhibition by aldoses and a possible mechanism. PMID- 4287006 TI - The epidemiology of a herpes virus infection of New World monkeys. PMID- 4287007 TI - [Growth rate on HeLa cells of virulent and attenuated strains of the poliomyelitis virus]. PMID- 4287008 TI - [Neural determinations of Hand-Schuller-Christian disease. (Study of an anatomo clinical case)]. PMID- 4287009 TI - [Hepato-splenic sarcoidosis with portal hypertension]. PMID- 4287010 TI - [The median line of the cervico-occipital joint. Study of an intervestibular line]. PMID- 4287011 TI - [Splenic scintigraphy]. PMID- 4287012 TI - [Treatment of asthma and allergic diseases by anesthetic retro-styloid infiltrations of the autonomic nervous system]. PMID- 4287013 TI - [Apropos of a case of cystosarcoma phyllodes on a mammary node in an aberrant site]. PMID- 4287014 TI - Infectious bovine rhinotracheitis abortion and its relationship to nutrition in California beef cattle. PMID- 4287016 TI - Growth and cytochrome c oxidase activity in minute mutants of Drosophila. PMID- 4287015 TI - Fine structure of the prostatic epithelium of the opossum (Didelphis virginiana Kerr). PMID- 4287017 TI - Kinetic criteria of solid state mechanisms in biology. PMID- 4287018 TI - Influence of polymyxin B and normal rabbit serum on erythrocyte modifying capacity of common enterobacterial antigen. PMID- 4287019 TI - [The use of liposoluble contrast media in angiography]. PMID- 4287020 TI - Respiratory syncytial virus epidemic. PMID- 4287021 TI - [Seriological studies on parainfluenzal infections of type 1 and 3 in Moldavia]. PMID- 4287023 TI - [Current possibilities of radiological examination in the diagnosis of renal tumors in children]. PMID- 4287022 TI - [Cytomegalic inclusion disease]. PMID- 4287024 TI - DNA synthesis in rat embryo cells infected with polyoma virus. PMID- 4287025 TI - The early synthesis of RNA in polyoma virus development. PMID- 4287026 TI - Early events in the eclipse phase of influenza and parainfluenza virus infection. PMID- 4287027 TI - Enzyme induction in SV40-infected green monkey kidney cultures. PMID- 4287028 TI - Glucocorticoid suppression from aldosteronomas. PMID- 4287030 TI - Calcification pancreatic carcinoma. PMID- 4287029 TI - Granular cell myoblastoma of the breast. PMID- 4287032 TI - Strain-specific mammary tumor virus activity in blood of C3H and BALB-c f. C3H mice. PMID- 4287033 TI - Mammary tumor virus activity in red blood cells of BALB-c f. C3H mice. PMID- 4287034 TI - Bizarre gastric leiomyoblastoma simulating a pedunculated uterine fibromyoma. PMID- 4287031 TI - Symposium on replication of viral nucleic acids. 3. Replication of mengovirus ribonucleic acid. PMID- 4287036 TI - [Occurrence of different morphologic forms of Bordetella pertussis]. PMID- 4287035 TI - Congenital and acquired cytomegalovirus infection. PMID- 4287037 TI - [Growth of the periosteum and age determination in mammals]. PMID- 4287038 TI - An histologic and histochemical study of familial osteoectasia. (Chronic idiopathic hyperphosphatasia). PMID- 4287040 TI - [Contribution to the knowledge of enzyme properties and of the function of the rat thyroid in various ages of life]. PMID- 4287039 TI - [Contribution to the knowledge of hypophyseal enzyme activity (adeno- and neurohypophyses)]. PMID- 4287041 TI - [On the regular histopathologic varieties of synovial sarcomas]. PMID- 4287042 TI - The association of aniridia, Wilms' tumor, and genital abnormalities. PMID- 4287043 TI - Center for the treatment of gestational trophoblastic neoplasms. PMID- 4287044 TI - Aberrant salivary tumours. (Report of four cases). PMID- 4287045 TI - Immunology of the mouse mammary tumour virus (MTV): a qualitative in vitro assay for MTV. PMID- 4287046 TI - Kinetic differences between human red cell and leucocyte pyruvate kinase. PMID- 4287047 TI - Mycotoxicosis: toxic fungi in tobaccos. AB - Cigarette, cigar, and pipe tobaccos contain Alternaria spores and dematiaceous mycelia, with cigarette tobaccos being more heavily laden. A smoke aerosol generated from hay on which the fungus had been cultured caused, among other pathologic changes, pulmonary emphysema in mice. PMID- 4287048 TI - Growth-hormone deficiency in man: an isolated, recessively inherited defect. AB - A deficiency of human growth hormone not associated with other pituitary deficiencies was observed in midgets with sexual ateliosis, a form of dwarfism inherited as an autosomal recessive trait. Body proportions, sexual development, birth weight, and postpartum lactation are normal in this syndrome. PMID- 4287049 TI - Satellites and nursing care. PMID- 4287050 TI - Nursing: yesterday, today and tomorrow. PMID- 4287051 TI - The limited role of attenuated smallpox virus in the management of advanced malignant melanoma. PMID- 4287052 TI - Possible "allosteric" effects controlling the kinetic behavior of amino acid dependent pyrophosphate exchange reactions. PMID- 4287053 TI - A nuclease specific for heat-denatured DNA in isolated from a product of Aspergillus oryzae. PMID- 4287054 TI - The reaction of radicals induced in Escherichia coli B-r by gamma-rays with cysteamine and with oxygen. PMID- 4287055 TI - Studies of the primary structure of 18-S + 28-S ribonucleates. PMID- 4287056 TI - Trophoblastic disease. Concepts of management. AB - Trophoblastic tumors are a notoriously unpredictable group in which metastasis may occur from histologically benign tumors and cause death, whereas a histologically malignant tumor may spontaneously disappear. Additional problems are created by the inability to accurately establish a diagnosis before abortion of molar tissue or development of metastasis.In recent years chemotherapy has dramatically improved the prognosis of patients with choriocarcinoma. This fact, plus the importance of the time interval between onset of disease and the beginning of chemotherapy, makes close follow-up of patients with trophoblastic tumors imperative.Concepts of therapy for trophoblastic tumors are rapidly changing. Indications for chemotherapy are broadening, especially in the areas of persistent and metastatic trophoblastic disease. As surgical intervention in the form of hysterectomy is becoming less important, the reproductive capacity of these young women is being preserved. Astute diagnosis, appropriate therapy and active life-long follow-up are the essentials in the management of patients with trophoblastic disease. PMID- 4287057 TI - [Excretion of tetra and hexahydro metabolites of delta-4-pregnenediol-(17 alpha,21)-dione-(3,20) under normal circumstances and under ACTH loading]. PMID- 4287058 TI - Benzothiadiazine suppression of insulin release from normal and abnormal islet tissue in man. PMID- 4287060 TI - Specific transplantation immunity in relation to Rous sarcoma virus tumorigenesis in mice. AB - Tests for transplantation immunity and for the occurrence of virus-neutralizing serum antibodies were performed on mice, inoculated when newborn with the Schmidt Ruppin strain of Rous sarcoma virus (RSV-SR). Mice developing no palpable primary sarcomas showed a clear-cut resistance against the isografting of established specifically antigenic Rous tumors. Transplantation tests performed on primary tumor hosts after extirpation of the tumors revealed neither any clear-cut immunity nor tolerance to the specific transplantation antigen(s). Serial pretreatment of operated primary tumor animals with irradiated autologous or syngeneic tumor cells resulted in a clear-cut transplantation immunity. Virus neutralizing activity was only found in a few sera from newborn infected mice, and in these cases there was no positive correlation with the transplantation immunity. It seems probable that a successful immunization against the RSV-SR specific transplantation antigen(s) prevents the development of primary tumors. There is no indication of any tolerance to this antigen in connection with the induction of primary tumors. PMID- 4287059 TI - The effects of combined renal vasodilatation and pressor agents on renal hemodynamics and the tubular reabsorption of sodium. PMID- 4287062 TI - D(-)-lactate dehydrogenase in lower fungi. AB - A lactate dehydrogenase, specific for nicotinamide-adenine dinucleotide and D(-) lactate, has been detected in extracts from two fungi of the order Leptomitales (Oomycetes). Several fungi of this order carry out a lactic acid fermentation under conditions of reduced oxygen tension. PMID- 4287061 TI - [Favorable results of ACTH therapy in different types of epilepsy resistant to all classical drug therapy (21 cases followed-up for more than 6 months)]. PMID- 4287063 TI - Mast cells and necrosis. AB - Subcutaneous injections of normally well tolerated amounts of hypertonic NaCl or urea solutions produce extensive topical necroses in rats systemically treated with various mast-cell dischargers and mast-cell products. This response is considered to be closely related to mitast-cell function, for it cannot be duplicated by systemic treatment with a variety of other agents. PMID- 4287064 TI - Puromycin analogs: action of adrenocorticotropic hormone and the role of glycogen. AB - The effect of the injection into rats of analogs of puromycin, 6 dimethylaminopurine, and the aminonucleoside of puromycin on the stimullation of steroidogenesis by adrenocorticotropic hormone was coin pared with that of puromycin and cycloheximide. This stimulation was blocked only by the antibiotics, which also inhibited adrenal protein synthesis. Glycogenolysis is not associated with the primary mechanism of the adrenocorticotropic hormone stimnulation of steroid hormone biosynthesis in rats. PMID- 4287065 TI - Chemotherapy in women with trophoblastic disease: choriocarcinoma, chorioadenoma destruens, and complicated hydatidiform mole. PMID- 4287066 TI - A study of cystosarcoma phyllodes. PMID- 4287068 TI - Primary carcinoma of the liver in Alberta. AB - A survey was made to determine the incidence and to elucidate the manifestations of primary carcinoma of the liver in Alberta. The findings were compared with other reported series. Ninety-six cases were identified: 69 hepatomas, 25 cholangiomas and two cholangiohepatomas. Seventy-four of the patients were male and 22 were female, a male preponderance of greater than 3:1. Ages ranged from 7 days to 92 years, but the majority of the patients (58%) were in the seventh and eighth decades. The incidence of associated cirrhosis (38.5%) was lower than that noted in most series.Hepatomegaly, abdominal pain, weight loss and ascites were the outstanding clinical features. Gastrointestinal hemorrhage was frequent and second only to hepatic failure as the immediate cause of death. An abdominal mass and pleural effusion occurred in higher frequency than that cited in the literature. Associated disorders included peptic ulceration and cholelithiasis.Surgical biopsy was superior to needle biopsy in establishing the diagnosis. Laboratory tests and routine radiographs may be of diagnostic aid. PMID- 4287069 TI - Peripheral neuropathy in juvenile diabetes. PMID- 4287067 TI - Unusual tumors of the stomach. PMID- 4287070 TI - Observations on pathogenicity and immunogenicity of a cell-culture-modified foot and-mouth disease virus. PMID- 4287071 TI - Detoxified bacterial endotoxns. II. Preparation and biological properties of chemically modified crude endotoxins from Salmonella typhimurium. AB - Martin, William J. (University of Utah, Salt Lake City), and Stanley Marcus. Detoxified bacterial endotoxins. II. Preparation and biological properties of chemically modified crude endotoxins from Salmonella typhimurium. J. Bacteriol. 91:1750-1758. 1966.-Chemical modification of a crude endotoxin prepared by the Roschka-Edwards (RE) procedure from a strain of Salmonella typhimurium yielded products which were nontoxic for mice and had reduced fever effects in rabbits. A reduction in rabbit pyrogenicity of approximately 100 times was noted with a potassium periodate-treated RE preparation when compared with the parent RE preparation. Measured in a similar fashion, pyrogenicity of a potassium methylate treated RE preparation was reduced by a factor of 10 while pyrogenicity of a boron trifluoride RE preparation was unchanged. All of these endotoxoids, including the parent RE preparation, showed little toxicity for mice. Immunogenicity was determined in mice by comparing Boivin, RE, and endotoxoid preparations with a heat-killed, phenol-preserved (HP) vaccine prepared from the same strain of S. typhimurium. Employing a 10 ld(50) challenge, the protective immunogenicity of the respective vaccines was determined by active immunized mouse protection tests. Although two 100 mug immunizing doses of the Boivin, RE, and the respective endotoxoid preparations varied in mouse protection (potassium methylate RE > Boivin > RE > boron trifluoride RE > potassium periodate RE), it was evident that, with the exception of the potassium methylate preparation, the HP vaccine yielded greatest protection against the 10 ld(50) challenge with S. typhimurium. Further mouse protection experiments suggested that the minimal immunogenic dose of the potassium methylate RE vaccine preparation was approximately 50 mug. These data indicated an approximate fivefold difference between the minimal pyrogenic dose (10 mug) and the minimal immunogenic dose (50 mug). These findings further suggest that potassium methylate RE vaccine preparations should be considered in the search for less toxic enteric fever vaccines. PMID- 4287073 TI - Immunochemical study of parainfluenza virus (type 2) in amnion cells. AB - de Vaux St. Cyr, C. Columbia University, New York, N.Y.),and C. Howe. Immunochemical study of parainfluenza virus (type 2) in amnion cells. J. Bacteriol. 91:1911-1916. 1966.-Immunoelectrophoretic analysis of stable amnion cells in which parainfluenza virus (type 2) was being actively synthesized revealed at least three precipitating antigens not found in normal cells. These "new" antigens differed from viral neuraminidase and hemagglutinin in both specificity and electrophoretic mobility; their identity and function remain to be elucidated. PMID- 4287072 TI - Bordetella pertussis culture having only species factor 1. AB - Eldering, Grace (Michigan Department of Public Health, Grand Rapids), Jack Holwerda, and Julia Baker. Bordetella pertussis culture having only species factor 1. J. Bacteriol. 91:1759-1762. 1966.-Preston's description of Bordetella pertussis 353-Z as a culture possessing only factor 1 was confirmed by agglutination and agglutinin-adsorption tests. The ld(50) values of this culture for mice inoculated by the intracerebral route were approximately the same as that of B. pertussis 18-323, the challenge culture in mouse potency tests of pertussis vaccine. In mouse protection tests, vaccine prepared with the factor 1 culture protected as well against challenge with B. pertussis 18-323, which has a broad antigenic pattern, as did vaccines made with cultures possessing factors 2, 3, 4, and 5 in addition to factor 1. When two groups of similarly immunized mice were challenged with 353-Z and 18-323, respectively, much lower ed(50) values were obtained with the animals challenged with 353-Z. This was true whether a factor 1 vaccine or a vaccine with factors 1, 2, 3, 4, and 5 was tested. PMID- 4287074 TI - Plaque enhancement of enteroviruses by magnesium chloride, cysteine, and pancreatin. AB - Wallis, Craig (Baylor University College of Medicine, Houston, Tex.), Fred Morales, Joycelyn Powell, and Joseph L. Melnick. Plaque enhancement of enteroviruses by magnesium chloride, cysteine, and pancreatin. J. Bacteriol. 91:1932-1935. 1966.-Plaque formation of 21 echoviruses (types 1-6, 9, 13, 15-19, 23-26, 29-32) and 8 coxsackieviruses (B1-6, A7, and A9) was enhanced by increased concentrations of MgCl(2), l-cysteine, and pancreatin in agar overlay medium. In most cases, cationic and anionic polymers (diethylaminoethyl dextran, dextran sulfate, or protamine sulfate) were ineffective. All strains of poliovirus and group B coxsackieviruses were enhanced under agar by MgCl(2). Five of the eight coxsackieviruses tested were also enhanced by cysteine or pancreatin. Certain enteroviruses, which have been difficult to assay by plaque method, can now be quantified effectively by incorporation of additives such as MgCl(2), cysteine, or pancreatin into the overlay medium. PMID- 4287075 TI - Identification of enteroviruses by hemagglutination-inhibition. AB - Kern, Jerome (Pacific Research Section, Honolulu, Hawaii), and Leon Rosen. Identification of enteroviruses by hemagglutination-inhibition. J. Bacteriol. 91:1936-1942. 1966.-Approximately 40% of a group of 906 enterovirus isolates cytopathic for monkey cell cultures were found to possess hemagglutinins for human erythrocytes when tested at temperatures of 4 and 37 C and at pH 5.8 and 7.3. The hemagglutinating isolates could be classified by relatively simple techniques into 18 serotypes. Four of these serotypes, echovirus type 24 and coxsackievirus B types 1, 5, and 6, had not previously been known to include hemagglutinating strains. One serotype, Toluca-3, represented a previously unrecognized enterovirus, and two other serotypes may also represent previously unrecognized enteroviruses. PMID- 4287077 TI - Yaba tumor poxvirus synthesis in vitro. II. Adsorption, inactivation, and assay studies. AB - Yohn, David S. (Roswell Park Memorial Institute, Buffalo, N.Y.), Fanny R. Marmol, Victoria A. Haendiges, and James T. Grace, Jr. Yaba tumor poxvirus synthesis in vitro. II. Adsorption, inactivation, and assay studies. J. Bacteriol. 91:1953 1958. 1966.-Means to increase the efficiency of the Yaba tumor poxvirus assay in BSC-1 cell cultures were sought. A method was devised wherein 0.4 ml of each virus dilution was layered onto BSC-1 cells in 80-mm Leighton tubes and permitted to adsorb at 25 C for 18 hr prior to incubation at 35 C. The diluent found most reliable was medium 199 containing 50% bovine amniotic fluid adjusted to 2.0 mm calcium and 1.0 mm magnesium at pH 7.0. These modifications yielded highly reproducible titrations with a greater than twofold increase in assay sensitivity. Irreversible adsorption of Yaba virus by BSC-1 cells proceeds comparatively slowly at 25 to 33 C. Although the process is more rapid at 35 or 37 C, the increased thermal lability of the virus at these temperatures results in lower titers than with virus adsorbed at 25 C for longer periods of time. Yaba poxvirus appears to be 5 to 10 times more sensitive to thermal inactivation than vaccinia poxvirus. PMID- 4287076 TI - Effect of poliovirus on deoxyribonucleic acid synthesis in HeLa cells. AB - Ackermann, W. W. (University of Michigan, Ann Arbor), D. C. Cox, H. Kurtz, C. D. Powers, and S. J. Davies. Effect of poliovirus on deoxyribonucleic acid synthesis in HeLa cells. J. Bacteriol. 91:1943-1952. 1966.-Both poliovirus and arginine stimulated deoxyribonucleic acid (DNA) synthesis in cultures of HeLa cells which were preconditioned by incubation in a medium deficient in arginine. However, the number of cells producing DNA was unaffected. DNA synthesis in such preconditioned cells was 10 to 20% of the maximal value obtained with a full complement of amino acids. Inhibition of DNA synthesis was produced in these cultures either by increasing the multiplicity of exposure above 40 plaque forming units of virus per cell or by increasing the concentration of the deficient amino acid at the time of virus addition. Inhibition of DNA synthesis resulted from a reduction in the fraction of cells producing DNA. The concentration of arginine required for viral inhibition of DNA synthesis is greater than that for viral multiplication. PMID- 4287078 TI - Persistent cyclic herpes simplex virus infection in vitro. II. Localization of virus, degree of cell destruction, and mechanisms of virus transmission. AB - Hampar, Berge (National Institute of Dental Research, Bethesda, Md.). Persistent cyclic herpes simplex virus infection in vitro. II. Localization of virus, degree of cell destruction, and mechanisms of virus transmission. J. Bacteriol. 91:1959 1964. 1966. The localization of virus, degree of cell destruction, and mechanisms of virus transmission in persistent herpes simplex virus-infected cultures were studied. The major fraction of infectious virus was associated with the medium and a minor fraction was associated with the attached cells. Virus in the medium was further separable into a sedimentable (cellular) fraction and a nonsedimentable (extracellular) fraction. The sedimentable fraction was comprised of cellular debris, most of which appeared to contain viral antigen, and intact cells of which less than 10% contained infectious virus. Cell destruction during the cycle involved more than 99.9% of the maximal number of cells present. Infection could be transmitted by extracellular virus, cell-to-cell transfer, and reattachment of infectious cellular material. The results indicated that transmission by reattachment was probably mediated through the cellular debris rather than the intact cells. PMID- 4287079 TI - Comparative study of seven picornaviruses of man. AB - Jamison, Richard M. (Baylor University College of Medicine, Houston, Tex.), and Heather D. Mayor. Comparative study of seven picornaviruses of man. J. Bacteriol. 91:1971-1976. 1966.-The buoyant densities in CsCl and potassium tartrate of seven acid-resistant picornaviruses of man were determined. The viruses studied were found to be a relatively homogeneous group. Buoyant densities ranged from 1.32 to 1.35 g/cc in CsCl and 1.21 to 1.23 g/cc in potassium tartrate. The buoyant density of each virus did not vary by more than 0.01 g/cc. The host cell of origin and passage level did not influence the buoyant density of the virions. However, measurements of the diameters of purified virions by a standard method have shown that there are considerable size variations among these picornaviruses. The diameters ranged from 18 to 25 mmu. Echovirus 19 and poliovirus 1 were significantly larger (mean diameter, 23.5 mmu) than echoviruses 4, 6, 16, and 23, and coxsackievirus B2 (mean diameter, 21.0 mmu). PMID- 4287081 TI - Studies on Japanese B encephalitis virus vaccines from tissue culture. VI. Development of a hamster kidney tissue culture inactivated vaccine for man. (1). Obtaining maximum titers of virus using an attenuated strain of OCT-541. PMID- 4287080 TI - Yaba tumor poxvirus synthesis in vitro. I. Cytopathological, histochemical, and immunofluorescent studies. AB - Yohn, David S. (Roswell Park Memorial Institute, Buffalo, N.Y.), Victoria A. Haendiges, and James T. Grace, Jr. Yaba tumor poxvirus synthesis in vitro. I. Cytopathological, histochemical, and immunofluorescent studies. J. Bacteriol. 91:1977-1985. 1966.-Yaba tumor poxvirus synthesis in BSC-1 cell culture was followed sequentially with light microscopy, immunofluorescent microscopy, and various histochemical stains. The first evidence of infection was detected at 24 hr when nucleoli became hypertrophic, reflecting enhanced ribonucleic acid (RNA) synthesis. At 36 hr, deoxyribonucleic acid synthesis was detected in the cytoplasm. This was immediately followed by or associated with antigen synthesis at paranuclear sites and enhanced RNA synthesis in the cytoplasm. Cytoplasmic inclusions were readily apparent at 4 days in initially infected cells. Contiguous spread of virus was judged to have occurred around the third day of infection. The time required to complete the synthetic cycle from time of infection to production of infectious progeny was estimated to be of the order of 60 hr. This cycle is 6 to 10 times longer than for vaccinia virus. By light microscopy, cytopathic effects (CPE) were detectable in 5 days in heavily infected cultures. With 100 units or less of infectious virus, CPE was not readily detected until the 10th to 14th day. At this time, focal areas of infection classified either as microtumors or microplaques were present. Secondary foci appeared during the 4th week of incubation. PMID- 4287082 TI - Immunogenicity of inactivated parainfluenza type 1, type 2, and type 3 vaccines in infants. PMID- 4287083 TI - Interference in mouse leukemia: results and prospects. PMID- 4287084 TI - Subcellular particles associated with human leukemia as seen with the electron microscope. PMID- 4287085 TI - [Use of an indirect luminescence method for early detection of pertussis and parapertussis antibodies]. PMID- 4287086 TI - Granulosa- and theca-cell tumours and genital cancer. PMID- 4287087 TI - Antibody response of fish to viral antigens. PMID- 4287088 TI - Cooperative interaction between the GTP binding sites of glutamate dehydrogenase. PMID- 4287089 TI - A nuclear magnetic resonance study of substrate binding by yeast alcohol dehydrogenase. PMID- 4287090 TI - Isolation of 4-O-beta-N-acetylmuramyl-N-acetylglucosamine and 4-O-beta-N, 6-O diacetylmuramyl-N-acetylglucosamine and the structure of the cell wall polysaccharide of Staphylococcus aureus. PMID- 4287091 TI - Intracellular distribution of glucose-6-phosphatase and glycogen content in the developing chick liver. PMID- 4287092 TI - The role of epithelium and mesenchyme in the production of a collagenolytic enzyme and a hyaluronidase in the anuran tadpole. PMID- 4287094 TI - The effect of efferentiectomy and orchidectomy on the metabolism of the epididymis of the mouse. PMID- 4287093 TI - The metabolism of homogenates of the mouse epididymis. PMID- 4287095 TI - Transformation of hamster embryo cells in vitro by polyoma virus: morphological, karyological, immunological and transplantation characteristics. PMID- 4287097 TI - Peripheral neuromyopathy following chloroquine therapy. PMID- 4287096 TI - Gastric antisecretory and other pharmacologic studies on 2,2'-bipyridine. PMID- 4287098 TI - [Hemodynamic modifications induced by beta and alpha hypertensin]. PMID- 4287099 TI - [Intrasplenic administration of lipiodol "UF" I-131 in hepatic neoplasms. (Diagnostic and therapeutic possibilities)]. PMID- 4287100 TI - [Studies on the immunologic efficacy of live polio vaccines and propagation of the vaccine viruses. 3. Studies on the propagation of live polio vaccine viruses among institutionalized children]. PMID- 4287101 TI - [Studies on the immunologic efficacy of live polio vaccines and propagation of the vaccine viruses. 4. Studies on the propagation of live polio vaccine viruses]. PMID- 4287102 TI - [Cytochrome oxidase and succinic dehydrogenase activity during the process of human fetal development]. PMID- 4287103 TI - [Studies on the formation of digestive tract resistance to polioviruses. Data on the measurement of poliovirus neutralizing antibodies in fecal exduates]. PMID- 4287104 TI - [The phosphomonoesterases of different microfilaria]. PMID- 4287105 TI - [Specific mesenchymomas of the female gonads in childhood]. PMID- 4287106 TI - [Rare cases of gastric muscular neoplasms (benign myoblastoma, malignant myoma) with a pseudochondroid aspect from intense hyaline metamorphosis]. PMID- 4287107 TI - [Morphologic observations on tumors of the palatine salivary glands]. PMID- 4287108 TI - [Phosphoprotein phosphatase in rabbit erythrocytes]. PMID- 4287109 TI - [Effect of some cations on the inactivation by CCl-4 of microsomial glucose-6 phosphatase in vitro]. PMID- 4287110 TI - Effects of pituitary hormones and prefeeding N-hydroxy-N-2-fluorenylacetamide on the metabolism of this carcinogen and on physiologic parameters. PMID- 4287111 TI - Immunology of the mouse mammary tumor virus (MTV) : identification in vitro of mouse antibodies against MTV. PMID- 4287112 TI - Non-respiratory oscillations in systemic arterial pressure of dogs. PMID- 4287113 TI - Hodgkin's granuloma complicated by generalized cytomegalic inclusion disease and gastrointestinal moniliasis. AB - A case is described in which Hodgkin's disease was complicated by inclusion disease and gastrointestinal moniliasis. This is one of several cases of malignant disease complicated by uncommon infections. PMID- 4287114 TI - Pedunculated islet-cell tumour of the duodenum. AB - An unusual islet-cell tumour found at necropsy in a patient who had died from a myocardial infarction is described. Of particular interest were the pedunculated nature and large size of the tumour. The clinical features of the case are considered. Four islet-cell tumours in the duodenum have previously been reported and it seems probable that such tumours arise in heterotopic pancreas. PMID- 4287115 TI - Assessment of hypothalamic pituitary function in endocrine disease. AB - The insulin test carried out with adequate safeguards under standardized conditions yields valuable information regarding hypothalamic and pituitary function when plasma levels of sugar, cortisol, and growth hormone are determined. The use of a test based on the plasma cortisol response to the infusion of lysine-vasopressin, a polypeptide with a corticotrophin-releasing action, is also of value as a test of pituitary function. Used in conjunction with the insulin test it enables pituitary disorders to be differentiated from those involving the hypothalamus. PMID- 4287116 TI - Nitrofurantoin and peripheral neuropathy with megaloblastic anaemia. PMID- 4287117 TI - Antibiotic effect of tylosin on a mycoplasma contaminant in a tissue culture leukemia cell line. PMID- 4287118 TI - Dissociation of adult mouse liver by sodium tetraphenylboron, a potassium complexing agent. PMID- 4287119 TI - Effects of a hepatocarcinogenic diet on adrenal glands and liver of rats. PMID- 4287120 TI - Collagenase activity of gingival tissue from patients with periodontal disease. PMID- 4287121 TI - Relationship between the lactic dehydrogenase-elevating virus and transplantable murine tumors. PMID- 4287122 TI - Hydrocephalus in mice infected with polyoma virus. PMID- 4287123 TI - Virus-induced transplantation immunity to human adenovirus type 12 tumors of the hamster and mouse. PMID- 4287125 TI - Attempt at immunization by oral feeding of live rhinoviruses in enteric-coated capsules. PMID- 4287124 TI - Skeletal response to exogenous ascorbic acid by vitamins D3 deficient chicks. PMID- 4287126 TI - [On bronchial adenoma]. PMID- 4287127 TI - [Inactivation of the vacuolating virus (SV40) with beta-propiolactone]. PMID- 4287128 TI - [Study on serum neutralizing antibody to poliovirus in healthy children. 2. Annual changes in the distribution of the serum neutralizing antibody to poliovirus by age in Kumamoto Prefecture]. PMID- 4287129 TI - The ultrastructure of acidophilic "Councilman-like" bodies in the liver. PMID- 4287130 TI - Effects of postnatal protein deficiency on weight gain, serum proteins, enzymes, cholesterol, and liver ultrastructure in a subhuman primate (Macaca mulatta). PMID- 4287132 TI - Clinical and pathological diagnosis. PMID- 4287131 TI - Pharmacological and biochemical studies on ethambutol in laboratory animals. PMID- 4287133 TI - Practical management of the nephrotic syndrome. Alternate day steroids and immunosuppressive therapy. PMID- 4287135 TI - [Use of adrenal cortex hormones in neurological diseases]. PMID- 4287134 TI - Temperature dependence of sodium ion activation of the cerebral microsomal adenosine triphosphatase. PMID- 4287136 TI - [Treatment of cardiac arrhythmia]. PMID- 4287137 TI - Complications and difficulties in electrocoagulation of varices of the lower extremities. PMID- 4287138 TI - Lymphangiographic studies in obstructive lymphedema of the upper extremity. PMID- 4287139 TI - [On the effect of carnitine and acylcarnitines on NADH2 oxidation]. PMID- 4287140 TI - The syntheses of peptides related to the N-terminal structure of corticotropin. VII. The synthesis of peptide derivatives corresponding to positions 11 to 18 in the corticotropin molecule. PMID- 4287142 TI - [Bizarre leiomyoblastoma of the stomach]. PMID- 4287141 TI - Isolation of skeletal muscle nuclei. AB - A method employing aqueous media for isolation of nuclei from rat skeletal muscle is described. The technique involves (a) mincing and then homogenizing in a 0.32 M sucrose-salt solution with a Potter-Elvehjem type homogenizer using a Delrin (an acetal resin) pestle and a carefully controlled, relatively large pestle-to glass clearance, (b) filtering through fiberglass and stainless steel screens of predetermined mesh size to remove myofibrils and connective tissue, and (c) centrifuging in a 2.15 M sucrose-salt solution containing 0.7 mM ATP. Electron and phase-contrast microscopic observations show that the nuclei are intact, unencumbered by cytoplasmic tags, and possess well preserved distinct nucleoli, nucleoplasm, and nuclear membranes. Cytoplasmic contamination is minimal and mainly mitochondrial. Chemical assays of the nuclear fraction show that the DNA/protein and RNA/DNA ratios are comparable to those obtained in other tissues. These ratios, as well as the low specific activity obtained for cytochrome c oxidase and the virtual absence of myofibrillar ATPase, indicate a high degree of purity with minimal mitochondrial and myofibrillar contamination. The steps comprising the technique and the reasons for their selection are discussed. PMID- 4287144 TI - Necrosis of the pancreas, parotid and lachrymal glands associated with encephalomyocarditis virus infection. PMID- 4287143 TI - Changes in electron spin resonance signals of rat liver during chemical carcinogenesis. PMID- 4287145 TI - A theory on the mechanism of carcinogenesis by small deoxyribonucleic acid tumour viruses. PMID- 4287146 TI - Interaction of 4-dimethylaminoazobenzene and dietary fat in the regulation of hepatic microsomal ascorbic acid synthesis. PMID- 4287147 TI - Inhibition of aortic calcification by means of pyrophosphate and polyphosphates. PMID- 4287148 TI - Altered cardiac retention of exogenous noradrenaline produced by stress in young rabbits. PMID- 4287149 TI - Effect of gossypol on some oxidative respiratory enzymes. AB - Gossypol was examined in relation to its effect on certain enzymes and enzyme complexes associated with the tricarboxylic acid cycle and the electron transport system. Succinic dehydrogenase and cytochrome oxidase activity from sweet potato was completely inhibited by gossypol at 7.5 x 10(-3)m and 2.0 x 10(-3)m, respectively. Succinoxidase activity of the same preparations was fully inhibited at a lower concentration, 2.5 x 10(-4)m. This concentration did not affect either succinic dehydrogenase or cytochrome oxidase, the primary and terminal enzymes of the succinoxidase complex. The nature of the intermediate step or steps inhibited at this concentration is not yet known. Gossypol was further shown to inhibit phosphorylation at concentrations having no appreciable effect on oxidation. Inhibition in general was not reduced by increased substrate concentrations in the enzyme systems examined, with the exception of cytochrome c for cytochrome oxidase. Bovine serum albumin was partially effective in reducing gossypol inhibition, provided that it was present before enzyme exposure to gossypol. PMID- 4287150 TI - [Xanthine oxidase--catalytic reaction and its mechanism]. PMID- 4287151 TI - [Biochemical applications of magnetic resonance spectroscopy, especially electron spin resonance]. PMID- 4287152 TI - Radiocalcium absorption at different times of day. PMID- 4287153 TI - [Complement-fixing sero-epidemiology for Myxovirus parainfluenzae types 1, 2, and 3 in various population samples]. PMID- 4287155 TI - [Observations on the chemical composition of cultures of the foot-and-mouth disease virus in relation to some phases of purification of the viral suspension]. PMID- 4287154 TI - [Contribution to the study of tumors of the sudoriferous glands of apocrine secretion in the dog]. PMID- 4287156 TI - [Clinical and therapeutic considerations on mixed salivary gland tumors]. PMID- 4287157 TI - [Experimental study of the adrenal cortex and hypothalamo-hypophyseal regulatory zones under the influence of hydrocortisone administration]. PMID- 4287159 TI - Insulin-induced hypoglycemia as a test of pituitary-adrenal function in thyrotoxicosis. PMID- 4287158 TI - [On the reduction of L-malic acid by lactic acid bacteria. I. On malate reducing enzymes of bacterium "L" with special attention to oxalacetate decarboxylase]. PMID- 4287160 TI - Postoperative studies of adrenal function in primary aldosteronism. PMID- 4287161 TI - [Disseminated herpes in an adult presenting a constitutional eczema]. PMID- 4287162 TI - [Immunological study of the polymorphism of human urinary phosphatases]. PMID- 4287163 TI - [Clinical application of synthesized peptide hormones with special reference to synthesized ACTH]. PMID- 4287164 TI - 1-Adamantanamine hydrochloride: inhibition of Rous and Esh Sarcoma viruses in cell culture. AB - I-Adamantanamine hydrochloride, added to chick embryo cells, inhibited focus production upon subsequent inoculation of the cells with Rous and Esh sarcoma viruses. Addition of the chemical to suspensions of Rous and Esh viruses before they were added to chick cell cultures did not inactivate the viruses; and the addition to chick cells did not prevent plaque formation following their inoculation with Newcastle disease virus. This indicates that cells treated with 1-adamantanamine hydrochloride are capable of supporting viral replication, and these observations suggest that the drug inhibits growth of two oncogenic viruses by prevention of virus penetration, but not by a virucidal effect or cell intoxication. PMID- 4287165 TI - Polysomes and protein synthesis in cells infected with a DNA virus. AB - In HEp-2 cells infected with herpes simplex virus the rate of protein synthesis at first decline, is stimulated between 4 and 8 hours after infection, and progressively and irreversibly declines from 9 to 16 hours later. The increase and decrease in rates coincide with corresponding changes in the amounts of cytoplasmic polysomes and amounts of labeled amino acids in nascent peptides bound to polysomes. The data indicate that (i) early and late inhibition and intervening stimulation of protein synthesis are due to the corresponding breakdown and formation of polysomes, and (ii) the bulk of viral proteins is probably made on cytoplasmic polysomes. PMID- 4287166 TI - Studies on the pathogenicity of various strains of Entamoeba histolytica after prolonged cultivation, with observations on strain differences in the rats employed. PMID- 4287167 TI - Studies of arthropod-borne virus infections in Chiroptera. 3. Influence of environmental temperature on experimental infection with Japanese B and St. Louis encephalitis viruses. PMID- 4287168 TI - Studies of arthropod-borne virus infections in Chiroptera. IV. The immune response of the big brown bat (Eptesicus f. fuscus) maintained at various environmental temperatures to experimental Japanese B encephalitis virus infection. PMID- 4287169 TI - Cytomegalic inclusion disease. An electron microscopic histochemical study of the virus at necropsy. PMID- 4287170 TI - Experimental myocardial infarction. A histochemical study. PMID- 4287171 TI - Experimental endocarditis. Endocrine factors in valve lesions on AV shunt rats. PMID- 4287172 TI - Production of hypertension and vascular disease by angiotensin. PMID- 4287173 TI - [Inhibitory action of adenosine triphosphate on human hepatoma aldolase]. PMID- 4287174 TI - [On 2 cases of tracheobronchial cylindroma]. PMID- 4287175 TI - Pentobarbital sleeping time and RES stimulation. PMID- 4287176 TI - [Gas gangrene in the abdominal wall following gastrectomy]. PMID- 4287177 TI - [Gas gangrene]. PMID- 4287178 TI - [Malignant neoplasms in childhood among radiological patients]. PMID- 4287179 TI - Studies on the hand in ulnar nerve paralysis. A clinical-experimental investigation in normal and anomalous innervation. PMID- 4287180 TI - [Experimental herpes simplex encephalitis of mice demonstrated by the fluorescent antibody method]. PMID- 4287182 TI - Studies on the biosynthesis of the corrin ring of vitamin B 12. PMID- 4287181 TI - Conformational changes and the regulation of glutamate-dehydrogenase activity. AB - 1. The effect of NADH and the non-competitive inhibitor GTP on the optical rotatory-dispersion properties of glutamate dehydrogenase has been studied. 2. Analysis of the data in terms of the a(0) and b(0) parameters of the Moffitt-Yang equation indicates that a conformational change is induced either by NADH or by GTP in the presence of small amounts of NADH. 3. Sedimentation measurements under comparable conditions showed that the enzyme reversibly dissociates into sub units but that this dissociation is only secondary to the conformational changes. 4. Fluorescence measurements showed that the binding constant of NADH and the number of binding sites on the enzyme increased in the presence of GTP. 5. This is confirmed by studies of fluorescence polarization, which in addition showed that the movement of NADH on the enzyme surface is more restricted in the presence of GTP. 6. The relation of these results to possible regulatory mechanisms is discussed. PMID- 4287183 TI - A rat-tissue aminotransferase acting on L-tyrosine O-sulphate. AB - 1. Rat tissues have been shown to possess an aminotransferase that is active towards l-tyrosine O-sulphate and dependent on 2-oxoglutarate and pyridoxal phosphate. 2. Kidney, liver and pancreas have the greatest activity and the enzyme is localized mainly in the mitochondrial fraction in the liver and kidney cell. 3. The enzyme was shown to be distinct from l-tyrosine-2-oxoglutarate aminotransferase but its true identity was not established. 4. A procedure for the assay of the enzyme in crude tissue preparations was developed. PMID- 4287184 TI - The differentiation and assay of vitamins D2 and D3 by gas-liquid chromatography. AB - 1. A method is described for the differentiation and determination of as little as 0.2mug. of vitamins D(2) and D(3) by gas-liquid chromatography. 2. The vitamins are converted by treatment with antimony trichloride into isovitamins D(2) and D(3), which show single, separate peaks on gas-liquid chromatography, unlike the unmodified vitamins, which give twin peaks due to the formation of pyro and isopyro derivatives. 3. Since isovitamins D(2) and D(3) remain together in all steps of the procedure except during gas-liquid chromatography, one may be used as an internal standard for the other. 4. The use of an internal standard reduces the importance of loss during sample preparation and increases precision. 5. The application of the method to biological materials is demonstrated. PMID- 4287186 TI - The incorporation of thymidine into deoxyribonucleic acid in mouse fibroblasts infected with polyoma virus. AB - 1. Mouse-fibroblast cultures in the stationary phase of growth show an increased rate of [(3)H]thymidine incorporation into DNA from 12 to 44hr. after infection with polyoma virus. 2. Intracellular virus progeny is first detected at about 24hr. after infection. 3. Calculations based on the [(3)H]thymidine-incorporation data and direct measurements of the DNA content of the cell cultures indicate that the amount of the excess of DNA synthesized by the infected cell cultures corresponds to about 10% of their total DNA. 4. The mitotic index of the cell cultures at 40hr. after infection was significantly higher than that of non infected control cells. 5. Possible interpretations of the stimulation of DNA synthesis observed in polyoma-infected cell cultures are discussed. PMID- 4287185 TI - Incorporation of injected [32P] phosphate into the phosphoinositides of subcellular fractions from young rat brain. AB - 1. Six subcellular fractions were prepared from the brain of 3-week-old rats after the injection of [(32)P]orthophosphate into the subarachnoidal space. The fractions were characterized by chemical and enzymic determinations and by electron microscopy. 2. The highest concentration of phosphoinositides was found in the microsomal fraction. 3. After an exchange period of 4hr. in vivo, the specific radioactivity of phosphatidylinositol was high in the nuclear, mitochondrial and supernatant fractions, and that of diphosphoinositide was high in the nuclear, microsomal and supernatant fractions. Triphosphoinositide specific activity was highest in the myelin fraction. 4. Specific activities (counts/100sec./mug. of P) were in the following order for all fractions except myelin: diphosphoinositide>phosphatidylinositol>triphosphoinositide. For myelin the order was: diphosphoinositide>triphosphoinositide>phosphatidylinositol. 5. Phosphatidylinositol extracted from a tissue fraction by acidified chloroform methanol had roughly twice the specific activity of that extracted by neutral solvents. The same applied to diphosphoinositide. PMID- 4287188 TI - [On age-related characteristics of the sensitivity of tissues to hormonal effects]. PMID- 4287189 TI - [A case of granular cell myoblastoma of penis]. PMID- 4287190 TI - Giant malignant tumor of the mouth; unusually long follow--up. PMID- 4287191 TI - [Adrenal cortical functional changes in endarteritis obliterans]. PMID- 4287187 TI - The inhibition of enzymes by beryllium. AB - 1. The action of beryllium on the following enzymes has been examined: alkaline phosphatase (Escherichia coli and kidney), acid phosphatase, phosphoprotein phosphatase, apyrase (potato), adenosine triphosphatase (liver nuclei, liver mitochondria, brain microsomes), glucose 6-phosphatase, polysaccharide phosphorylases a and b, phosphoglucomutase, hexokinase, phosphoglyceromutase, ribonuclease, A-esterase (rabbit serum), cholinesterase (horse serum), chymotrypsin. Alkaline phosphatase and phosphoglucomutase are inhibited by 1mum beryllium sulphate whereas the other enzymes are largely unaffected by 1mm beryllium sulphate. 2. Possible mechanisms for the inhibition of phosphoglucomutase and alkaline phosphatase are discussed. PMID- 4287192 TI - The contribution of the carpal bones to the assessment of skeletal age. PMID- 4287193 TI - Effects of intravitreous injection of drugs on the cholinesterase of the retina. PMID- 4287195 TI - The suitability of silvered leaf monkey (Presbytis cristatus) kidney cell cultures for testing poliovirus vaccines. PMID- 4287194 TI - Studies on a skin calcifying system. PMID- 4287196 TI - Cardiac lymphangiography. A preliminary report on a roentgen study of the cardiac lymphatics in the dog. PMID- 4287197 TI - Lymphatico-venous communications and lymph reflux after thoracic duct obstruction. An experimental study in the dog. PMID- 4287198 TI - The effect of some sulfur-containing pyridine derivatives on the carbohydrate metabolism of Ehrlich ascites tumor. PMID- 4287199 TI - Studies on 2-(alpha-hydroxybenzyl)benzimidazole (HBB) analogs. I. Synthesis of 8 (alpha-hydroxybenzyl)purines, the diaza analogs of HBB. PMID- 4287200 TI - Studies on the transfer of subviral infectivity from SV40-induced hamster tumor cells to indicator cells. PMID- 4287201 TI - Radiation studies of avian tumor viruses and of Newcastle disease virus. PMID- 4287202 TI - Deoxyribonucleic acid synthesis in cells replicating polyoma virus. PMID- 4287203 TI - Properties of cells derived from adenovirus-induced hamster tumors by long-term in vitro cultivation. II. Nature of the restricted response to type 2 adenovirus. PMID- 4287204 TI - The inhibition of poliovirus growth by actinomycin D and the prevention of the inhibition by pretreatment of the cells with serum or insulin. PMID- 4287205 TI - Changes in metabolic and enzymatic activities of monkey kidney cells after infection with adenovirus 2. PMID- 4287206 TI - Antagonism of the guanidine interference with poliovirus replication by simple methylated and ethylated compounds. PMID- 4287207 TI - Electron microscopic localization of virus-associated antigens in human amnion cells (AV-3) infected with human adenovirus, type 12. PMID- 4287208 TI - High frequency of SV40 transformation of mouse cell line 3T3. PMID- 4287209 TI - The effect of SV40 infection on DNA synthesis in cercopithecus kidney cells. PMID- 4287210 TI - In vitro transformation of rat embryo cells by a murine sarcoma virus. PMID- 4287211 TI - Counteraction between interferon and enhancer. PMID- 4287212 TI - Studies on the alteration of species-specific resistance by ethionine-induced inhibition of protein metabolism. II. Infection experiments in rats with canine hepatitis (Rubarth-disease) virus. PMID- 4287213 TI - Plant tissue phosphodiesterase activities. PMID- 4287214 TI - A novel branched-chain sphingolipid base from Crithidia fasciculata. PMID- 4287215 TI - Purification and properties of nucleoside tetraphosphate hydrolase from rabbit muscle. PMID- 4287216 TI - Purification and properties of 3',5'-cyclic nucleotide phosphodiesterase from dog heart. PMID- 4287217 TI - Biosynthesis of uridine diphosphate D-xylose. II. Uridine diphosphate D glucuronate carboxy-lyase of Cryptococcus laurentii. PMID- 4287218 TI - Biosynthesis of phosphatidyl myoinositol phosphates in rabbit brain. PMID- 4287219 TI - Electron-transport systems of yeast. II. Purification and properties of a soluble reduced diphosphopyridine nucleotide dehydrogenase. PMID- 4287220 TI - Improvement in methodology for measurement of plasma renin activity. PMID- 4287221 TI - Activity of glycolytic and hexose monophosphate pathways in Yoshida ascites hepatomas. PMID- 4287222 TI - Studies on tissue culture of ascites tumors. I. Primary culture of rat ascites tumors. PMID- 4287223 TI - Studies on tissue culture of ascites tumors II. In vitro growth of mouse ascites hepatoma MH 134. PMID- 4287224 TI - Studies of induced malignant tumors of placental and uterine origin in the rat. I. Survival of placental tissue following fetectomy. PMID- 4287225 TI - Prophylactic chemotherapy of hydatidiform mole. PMID- 4287226 TI - Reconstruction of the hand in high median nerve injuries. PMID- 4287227 TI - Silica. PMID- 4287228 TI - [An electron microscopic observation on genital Paget's disease]. PMID- 4287229 TI - [Rheumatoid arthritis (in orthopedics)]. PMID- 4287230 TI - [Etiology and treatment of hirsutism]. PMID- 4287231 TI - A test of adrenal cortical function in dairy cows by ACTH administration. PMID- 4287232 TI - [Effects of a temporary limited respiratory inhibition by hydrocyanic acid on cell metabolism and developmental capacity of young amphibian embryos]. PMID- 4287233 TI - [Lymphangioadenography of the retroperitoneal lymph system]. PMID- 4287234 TI - Stiulation of growth of Bordetella pertussis by acetate. PMID- 4287235 TI - [Relation of quartz dust dose to the extent of inflammatory reaction of the lungs]. PMID- 4287236 TI - [On bilateral pleural calcifications in the roentgenogram in silicosis of quartz sandstone grinders. (Posture as a favorizing factor?)]. PMID- 4287238 TI - [Round table conference. Peripheral nerve injuries]. PMID- 4287237 TI - [Serum iron and the iron-binding capacity in tumor-bearing animals and humans]. PMID- 4287239 TI - [Apropos of the association of cancer of the kidney, neuromyopathy and hypercalcemia with hypophosphoremia. Discussion of a paraneoplastic hyperparathyroidism]. PMID- 4287240 TI - [Viral keukemogenesis in mice]. PMID- 4287241 TI - [Studies on biological behaviors of leukemogenic virus and role of thymus in AKR leukemogenesis]. PMID- 4287242 TI - Treatment of abortions infected with Clostridium welchii. PMID- 4287243 TI - [On a toxic and oxytocic Euphorbiaceae of the Ivory Coast: Mareya micrantha Muell. Arg]. PMID- 4287244 TI - Idiopathic non-inflammatory neuromyopathy. PMID- 4287245 TI - [Multiplication of vesicular stomatitis virus in Drosophila melanogaster]. PMID- 4287246 TI - [Age factor in the distribution of antibodies to parainfluenza viruses type 1,2 and 3]. PMID- 4287247 TI - [A possibility of converting smallpox viruses into vaccinia viruses under experimental conditions]. PMID- 4287249 TI - Effect of adrenal stimulation on histamine in the rat stomach. PMID- 4287248 TI - [Protective effect of homologous and heterologous immune sera in tissue culture experiments]. PMID- 4287250 TI - Tropical sprue: viral cultures of rectal swabs. PMID- 4287251 TI - [ESR studies on pyrrole derivatives, I. XII. On the Stokvis reaction]. PMID- 4287252 TI - Chemotherapy of malignant lesions unique in children. PMID- 4287253 TI - Hypoglycemia. PMID- 4287254 TI - Vasoactive polypeptides of surgical significance. PMID- 4287255 TI - Effect of Naja naja atra venom on cytochrome C oxidase, L-ascorbic acid oxidase, peroxidase, and catalase. PMID- 4287256 TI - Growth requirements and biologic characteristics of leukemia L1210 cells in culture. PMID- 4287257 TI - Persistent cyclic herpes simplex virus infection in vitro. 3. Asynchrony in the progression of infection and cell regrowth. AB - Hampar, Berge (National Institute of Dental Research, Bethesda, Md.). Persistent cyclic herpes simplex virus infection in vitro. III. Asynchrony in the progression of infection and cell regrowth. J. Bacteriol. 91:1965-1970. 1966.-The progression of virus-induced cytopathic effects (CPE) and virus synthesis was studied in localized areas of Chinese hamster cell cultures persistently infected with herpes simplex virus (HSV). CPE was initially evidenced by the presence of small multinucleated giant cells, followed by expanding plaquelike lesions with an occasional uninfected cell remaining within the infected areas. Cell detachment rapidly followed the appearance of viral antigen in infected cells. The surviving cells which proliferated to re-establish the cell sheet arose from two sources. The first was from viable cells which remained attached after expansion of localized areas of CPE, and the second was from reattachment of viable cells in the medium. CPE in localized areas was initiated at various times during the cycle irrespective of the virus titer in the medium. Cell regrowth in some areas and CPE in other areas occurred simultaneously throughout the cycle in an asynchronous fashion. Consequently, during periods of rising virus titers, most areas showed CPE while few areas displayed cell regrowth. As the virus titers declined, more areas showed cell regrowth and fewer areas displayed new cycles of CPE. CPE in localized areas was not initiated until cell regrowth had occurred. It is proposed that the proliferating cells were temporarily resistant to HSV infection, and that this resistance was ultimately lost in their progeny cells. PMID- 4287258 TI - Yaba tumor poxvirus synthesis in vitro. 3. Growth kinetics. AB - Yohn, David S. (Roswell Park Memorial Institute, Buffalo, N.Y.), Victoria A. Haendiges, and Etienne de Harven. Yaba tumor poxvirus synthesis in vitro. III. Growth kinetics. J. Bacteriol. 91:1986-1991. 1966.-The infectious synthetic cycle of Yaba poxvirus by BSC-1 cells at 35 C is described and discussed together with related observations obtained by immunofluorescence and electron microscopy. After adsorption of virus at 25 C, at least 6 hr of incubation at 35 C was required before viral eclipse was demonstrable. Infectious progeny appeared after an additional 48 hr of incubation at 35 C. Newly synthesized virus particles were seen at 68 hr but not at 44 hr by electron microscopy. Maximal maturation occurred between 100 and 120 hr. Maximal yields were obtained from the 5th through the 8th day. The differences in kinetics between Yaba and vaccinia poxviruses, as described for the latter in the literature, are discussed. Possible factors accounting for these differences are enumerated. PMID- 4287259 TI - Studies of the mechanism through which sodium depletion increases aldosterone biosynthesis in man. PMID- 4287260 TI - Animal--man cancer probes continue. PMID- 4287262 TI - [Clinical picture and treatment of insuloma]. PMID- 4287261 TI - Infusion of floxuridine in the treatment of solid tumors. PMID- 4287263 TI - Necrotizing colitis due to Clostridium welchii. PMID- 4287264 TI - Some recent work at the Common Cold Research Unit. PMID- 4287265 TI - A long-term study of acute respiratory diseases in a natural community. PMID- 4287266 TI - Effect of renin, angiotensin II and aldosterone on erythropoiesis. PMID- 4287267 TI - [Possible mechanisms of formation and destruction of free radical states cell]. PMID- 4287268 TI - [Separation, identification and comparative evaluation of adrenal steroids in urine extracts using thin-layer chromatography]. PMID- 4287269 TI - [The urinary secretion of ACTH in adrenal cortical hyperfunction]. PMID- 4287270 TI - [Adrenal reserve in adrenal cortical hyperfunction]. PMID- 4287271 TI - [Studies of the adrenocortical functional reserve with particular interest in its quantitative evaluation]. PMID- 4287272 TI - [Urinary excretion of electrolytes following ACTH administration--a functional test of the adrenal cortex]. PMID- 4287273 TI - [Evaluation of adrenal and pituitary functional reserve in patients with rheumatoid arthritis after prolonged corticoid treatment]. PMID- 4287274 TI - The effects of terminating and detraining on enzyme activities of heart and skeletal muscle of trained rats. PMID- 4287275 TI - The isolation of retinal outer segment fragments. AB - Bovine retinal outer segment fragments were isolated by density gradient centrifugation in a high centrifugal field. Assays of the final preparation for enzymes of the mitochondrial respiratory chain indicated mitochondrial contamination not in excess of 1 per cent. Glucose-6-phosphatase and TPNH cytochrome c reductase activities, presumably diagnostic for microsomes, were also absent. Electron micrographs did not disclose the presence of significant numbers of particles other than fragments of the outer segment discs. The red fragments were characterized by an ascorbate-oxidizing system and a high lipid content. PMID- 4287276 TI - Ribonucleic acid and protein synthesis in mitotic HeLa cells. AB - HeLa cells arrested in mitosis were obtained in large numbers, with only very slight interphase cell contamination, by employing the agitation method of Terasima and Tolmach, and Robbins and Marcus. Protein synthesis and RNA synthesis were almost completely suppressed in mitotic cells. Active polyribosomes were nearly absent in mitotic cells as compared with interphase cells treated in the same way. Cell-free protein synthesis and RNA polymerase activity were also greatly depressed in extracts of metaphase cells. The deoxyribonucleoprotein (DNP) of condensed chromosomes from mitotic cells was less efficient as a template for Escherichia coli RNA polymerase than was DNP from interphase cells, although isolated DNA from both sources was equally active as a primer. Despite very poor endogenous amino acid incorporation by extracts of metaphase cells, polyuridylate stimulated phenylalanine incorporation by a larger factor in mitotic cell extracts than it did in interphase cell extracts. These results suggest that RNA synthesis is suppressed in mitotic cells because the condensed chromosomes cannot act as a template, and that protein synthesis is depressed at least in part because messenger RNA becomes unavailable to ribosomes. This conclusion was supported by the demonstration that cells arrested in metaphase supported multiplication of normal yields of poliovirus, thereby showing that the mitotic cell is capable of considerable synthesis of RNA and protein. PMID- 4287277 TI - [The bacteriological diagnosis of whooping cough with fluorescent labeled antibodies]. PMID- 4287278 TI - Subcutaneous sarcomata in hamsters induced by Rous sarcoma virus (Bryan). PMID- 4287279 TI - Derivatives of 2-aminoethyl-guanidine and of a eugenol as virus inhibitors. PMID- 4287280 TI - [Rare case of suffocating emphysematous bulla of the lower lobe of the right lung]. PMID- 4287281 TI - [Studies on pig erythrocyte lipids. II. The isolation and the identification of individual lipids with some quantitative aspects on the composition of erythrocyte lipids]. PMID- 4287282 TI - Rise of cytomegalovirus antibodies in an infectious-mononucleosis-like syndrome after transfusion. PMID- 4287283 TI - [On benzenesulfonylamino-5-[beta-methoxyethoxy]-pyrimidine (glycodiazine). 3. Glycodiazine plasma concentration and blood sugar lowering effects in humans, as well as the influence of glycodiazine on the hypophyseal-adrenal cortex system]. PMID- 4287284 TI - [Gas chromatographic determination of acetic acid in biological material]. PMID- 4287285 TI - The structure of glycopeptide obtained from Taka-amylase A. PMID- 4287286 TI - The acid-soluble nucleotides of milk. IV. The chemical structure of UDP-X3. PMID- 4287288 TI - [Krukenberg tumor with primary appendiceal site]. PMID- 4287287 TI - A possible role for cytochrome b-555 in the mung bean mitochondrial electron transport system. PMID- 4287290 TI - Angiotensin infusions. PMID- 4287289 TI - Diagnostic and physiologic implications of the angiotensin infusion test. PMID- 4287292 TI - [DNA degradation and oxidation of o-phenylenediamine. Metal ions and H2O2, 8]. PMID- 4287291 TI - Estimation of free methylpentoses in the presence of glycosidically bound sugar. PMID- 4287293 TI - [Value of the use of primyxine pomades in infected dermatoses]. PMID- 4287294 TI - [Contribution to the study of peripheral vascular reactivity to angiotensin and noradrenaline in the course of hepatic diseases]. PMID- 4287295 TI - Observations on epiphyseal fusion of the canine appendicular skeleton. PMID- 4287296 TI - Usefulness of the brain scan in therapeutic radiology. PMID- 4287297 TI - [Enzymatic NAD conversion in extracts of normal and denervated skeletal muscles]. PMID- 4287299 TI - Determination of 17-hydroxycorticosteroids in canine urine. PMID- 4287298 TI - Effect of chemical agents on foot-and-mouth disease virus production in cell cultures. PMID- 4287300 TI - Deamidation of adenosine phosphoramidate by hog eye ciliary process. PMID- 4287301 TI - Oxidative activity of crab gill mitochondria as a function of osmotic concentration. PMID- 4287302 TI - Amino acid activating enzymes in Sarcophaga bullata. PMID- 4287304 TI - A mixed layer for separation of amino acids by thin-layer chromatography. PMID- 4287303 TI - Active cation transport and ATP hydrolysis in Acanthamoeba sp. PMID- 4287305 TI - A sensitive reagent for detecting 2-deoxysugars and 3-deoxypolyols. PMID- 4287306 TI - Thin-layer chromatography on silica gel: quantitative analysis by direct U.V. spectrophotometry. PMID- 4287307 TI - Transesterification of lecithin on silicic acid columns. PMID- 4287308 TI - [Myeloencephalography with opaque contrast media]. PMID- 4287309 TI - Pancreatic cysts occurring secondary to ductal carcinoma of the pancreas. PMID- 4287310 TI - The angiotensin infusion test: preliminary experience. PMID- 4287312 TI - [Biochemical determination of the phosphomonoesterase activity in the intestine and kidney of Bufo bufo bufo L]. PMID- 4287311 TI - Granular cell myoblastoma of the pituitary body simulating a chromophobe adenoma. PMID- 4287313 TI - [The role of mucopolysaccharides in atherosclerosis]. PMID- 4287314 TI - Wilms' tumor--metastatic to the lung. Report of a survivor with radiation therapy only. PMID- 4287315 TI - [On treatment of uterine bleeding caused by hormonal disorders]. PMID- 4287316 TI - [Confirmation of the presence of NAD in part of the brain in mice and the effect of hydrazine-2HCl]. PMID- 4287317 TI - [Synthesis of 17,18-diornithine-beta-corticotropin-(1-24)-tetracosapeptide, a biologically active analogue of adrenocorticotropic hormone]. PMID- 4287318 TI - [Laboratory method of using electron spin resonance]. PMID- 4287319 TI - [Development of adjuvant-arthritis in the methopyranon-treated rat]. PMID- 4287320 TI - [On the localization of the free radicals induced by ionizing radiation in solid phase desoxyribonucleic acid]. PMID- 4287321 TI - [Action of catecholamines on the cytochrome C-cytochrome-oxidase system in vitro]. PMID- 4287322 TI - Viraemia following polio vaccination with Sabin type 1 strain LSc2ab. PMID- 4287323 TI - [Symposium on the significance of enzymes in the field of internal medicine. (6). Renal hypertension and angiotensinase]. PMID- 4287324 TI - [The behavior of succinate dehydrogenase and NADH-cytochrome-c-reductase in rat liver, spleen and thymus mitochondria after irradiation in vivo]. PMID- 4287325 TI - [Experimental research in murine leukemia. X. Pathogenicity of suspensions of human fibroblastic cells, infected with virus C57, for the developing chick embryo]. PMID- 4287326 TI - [Study of the relations between the etiology and serum electrophoretic changes in patients with acute rickettsial, para-rickettsial, adenoviral and influenzal pneumopathies]. PMID- 4287327 TI - Aspects of the synthesis of poliovirus RNA and the formation of virus particles. PMID- 4287328 TI - Genetic basis of cellular susceptibility to the Schmidt-Ruppin and Harris strains of Rous sarcoma virus. PMID- 4287329 TI - [Morphogenesis of cultures of the transplantable cells CA-SV40-63-1]. PMID- 4287330 TI - Viral causes of bovine abortion in Ohio. PMID- 4287331 TI - Clostridium perfringens myometritis complicating cesarean section. Report of 2 cases. PMID- 4287332 TI - Extracranial metastases from central nervous system tumors in children and adolescents. PMID- 4287333 TI - An analysis of circadian rhythms in human adrenocortical secretory activity. PMID- 4287334 TI - Anal and perianal malignant neoplasms: pathology and treatment. PMID- 4287335 TI - Studies on the mechanism of nidation. XIX. Histochemical changes in the ovaries of pregnant rats following ergocornine. PMID- 4287336 TI - A simple method for measuring ribonucleic acid content of preparations of deoxyribonucleic acid. PMID- 4287337 TI - Action of angiotensin on sympathetic nerve endings in isolated blood vessels. PMID- 4287339 TI - Antiviral activity of p-nitrobenzylphosphonic acid. PMID- 4287338 TI - Inhibition of adrenocortical responsiveness to ACTH by actinomycin D in vivo. PMID- 4287340 TI - Haemolytic activity of suspensions of different silica modifications and inert dusts. PMID- 4287341 TI - Inhibition of encephalomyocarditis virus replication by simple phosphonic and carboxylic acids. PMID- 4287342 TI - Distribution of the nucleases of the microsomal fraction of rat liver between ribosomes and endoplasmic membranes. PMID- 4287343 TI - The localization of ulnar nerve compression in the hand and arm: an improved method of electroneuromyography. PMID- 4287344 TI - Energy-linked reactions in mitochondria. Studies on the reduction of NAD+ by succinate. PMID- 4287346 TI - Thermodynamic properties of an allosteric transition. PMID- 4287345 TI - The properties of a glycyl-soluble-RNA synthetase from chick embryo. PMID- 4287347 TI - Influence of substrate-induced enzymic inactivation on the sulfhydryl content of glyceraldehyde-3-phosphate dehydrogenase. PMID- 4287348 TI - Ribonucleases of the rat. 3. Localization by immunofluorescence. PMID- 4287349 TI - Vitamin A and the sulfate-activating enzymes. PMID- 4287350 TI - Comparison of guanosine triphosphate split and polypeptide synthesis with a purified E. coli system. PMID- 4287352 TI - [Pancreatic islet cell adenoma with the triad diarrhea, hypokalemia and hyperglycemia]. PMID- 4287351 TI - Potentiation of oncogenicity of adenovirus type 12 grown in African green monkey kidney cell cultures preinfected with SV40 virus. Persistence of both T antigens in the tumors and evidence for possible hybridization. PMID- 4287353 TI - [Gas gangrene-brain abscess following a "scalp wound"]. PMID- 4287354 TI - [Diagnosis of renal artery stenosis]. PMID- 4287355 TI - [Experimental research on the toxicity of the silicon ion. IV. Lesions of the lymphatic system due to silicic acid]. PMID- 4287357 TI - Inhibition of hyaluronic acid degradation by dimethyl sulphoxide. PMID- 4287356 TI - [Late functional results following ablation of various vocal cord hyperplasias]. PMID- 4287359 TI - Relation of cell size to the effect of x-rays on poliovirus production by monkey kidney cells. PMID- 4287358 TI - Effect of ethylenediamine tetraacetate on the resistance of Pseudomonas aeruginosa to antibacterial agents. PMID- 4287360 TI - Electron spin resonances in Formicidae. PMID- 4287361 TI - Vesicular exanthem of mixed bacterial-viral etiology. PMID- 4287362 TI - [Myelography with water-soluble iodine in intervertebral disk pathology]. PMID- 4287363 TI - [Alternating pulse and pseudogallop]. PMID- 4287364 TI - Healing following simple gingivectomy. A tritiated thymidine radioautographic study. I. Epithelialization. PMID- 4287365 TI - Nutritive value of Nigerian water melon. PMID- 4287366 TI - Structure of the pigments of precooked irradiated meats. PMID- 4287367 TI - Effect of aerobic pre-incubation of glycolysis in resting and proliferating liver cells. PMID- 4287368 TI - Transport of S-antigen of Sendai virus as revealed by means of antibody labelled with an organic mercury compound. PMID- 4287369 TI - Antibiotic carry-over in cell cultures of herpes simplex virus. PMID- 4287370 TI - The bacterial degradation of pantothenic acid. 3. Enzymatic formation of aldopantoic acid. PMID- 4287371 TI - The bacterial degradation of pantothenic acid. IV. Enzymatic conversion of aldopantoate to alpha-ketoisovalerate. PMID- 4287372 TI - The glycolipids of dog intestine. PMID- 4287373 TI - Primary oxidation-reduction changes during photosynthesis in Rhodospirillum rubrum. PMID- 4287374 TI - New acetylenic fatty acids from Acanthosyris spinescens seed oil. PMID- 4287376 TI - Involvement of CO2 in the Hill reaction. PMID- 4287377 TI - A simplified method for the extraction and bioassay of renin. PMID- 4287375 TI - Hormone control of connective tissue. PMID- 4287378 TI - [Improvement of biological cell activity by use of a siliconized container in incubation of free cells]. PMID- 4287379 TI - Studies on the transplantation of ascites hepatoma (AH 7974) into rat's uterine cervix. PMID- 4287381 TI - Demonstration of an avian leucosis group antigen by immunodiffusion. PMID- 4287382 TI - Electron spin resonance spectra of gamma-irradiated polycrystalline glycollic acid. PMID- 4287383 TI - Morphology of components of Sendai virus. PMID- 4287380 TI - [On the pathogenesis of herpesvirus diseases with special reference to necrotizing herpes simplex encephalitis]. PMID- 4287384 TI - Determination of the type of nucleic acid in rubella virus using 5-bromo-2' deoxyuridine. PMID- 4287385 TI - Cell growth and the initiation of transformation by SV40. PMID- 4287386 TI - Nucleic acid homology studies of adenovirus type 7-SV40 interactions. PMID- 4287387 TI - Immunofluorescent studies of group-specific antigen of the avian sarcoma-leukosis viruses. PMID- 4287388 TI - Energy transfer in dinucleotides. PMID- 4287389 TI - [The treatment of malignant tumors from the epithelium of mucous glands of the hard palate]. PMID- 4287391 TI - Isolation of Japanese encephalitis virus from the blood of a child in Singapore. PMID- 4287390 TI - Viral infections of monkeys in their natural habitat in southern India. II. Serological evidence of viral infection. PMID- 4287392 TI - Immunological studies with group B arthropod-borne viruses. V. Evaluation of cross-immunity against type 1 dengue fever in human subjects convalescent from subclinical natural Japanese encephalitis virus infection and vaccinated with 17D strain yellow fever vaccine. PMID- 4287393 TI - Cultivation of Entamoeba histolytica and Entamoeba histolytica-like strains at reduced temperature and behavior of the amebae in diluted media. PMID- 4287394 TI - Effect of amytal, pyridine nucleotides, and oxaloacetate on the respiratory inhibition-activation cycles in mitochondria. PMID- 4287395 TI - The intracellular nucleotides of Astasia longa. PMID- 4287396 TI - Ribonucleoside triphosphatase in rabbit reticulocytes. PMID- 4287397 TI - Purification and properties of an inhibitor for nicotinamide-adenine dinucleotidase from Mycobacterium tuberculosis H-37-Rv. PMID- 4287398 TI - Increase of mitochondrial content in sweet potato root tissue after wounding. PMID- 4287399 TI - [Apropos of 2 cases of cytomegalic inclusion disease and especially of a subacute encephalic and anicteric form in an African dizygotic twin newborn infant]. PMID- 4287400 TI - [A case of muco-epidermoid tumor of the mandible]. PMID- 4287401 TI - Membrane isolation and cytoskeletal breakdown. II. Enzyme studies revealing cytoskeletal stabilization by FAD. PMID- 4287402 TI - Erythropoietic differentiation of stable cell lines derived from hematopoietic organs of mice with virus-induced leukemia. PMID- 4287403 TI - Selective response of the Japanese quail to various strains of Rous sarcoma virus. AB - Shipman, Charles Jr. (Indiana University School of Medicine, Indianapolis), and Alvin S. Levine. Selective response of the Japanese quail to various strains of Rous sarcoma virus. J. Bacteriol. 92:161-163. 1966.-The Bryan "high-titer," Carr Zilber, Harris, Prague, Schmidt-Ruppin, and "29" strains of Rous sarcoma virus were used to initiate tumors in the Japanese quail (Coturnix coturnix japonica). Although all strains produced tumors upon primary inoculation, only the Bryan "high-titer" and Harris strains could be serially passaged with cell-free tumor extracts. Analysis by means of the end-point dilution technique and the interference test revealed that the tumor extract of the Bryan "high-titer" strain passaged 10 times in the quail contained a Rous-associated virus. PMID- 4287404 TI - Selective inactivation of biological activity of myxoviruses by glutaraldehyde. PMID- 4287405 TI - Effect of mycoplasma on interferon production and interferon assay in cell cultures. AB - Armstrong, D. (The Children's Hospital of Philadelphia, Philadelphia, Pa.), and K. Paucker. Effect of mycoplasma on interferon production and interferon assay in cell cultures. J. Bacteriol. 92:97-101. 1966.-The influence of mycoplasma on the production and action of interferon was studied in cultures of both L and human embryonic kidney (HEK) cells. Mycoplasma hominis 1, the Negroni agent, and the F12 mycoplasma were used for infection of L cells, and M. hominis 1 and M. pneumoniae for inoculation of HEK cells. All strains were capable of multiplication in the culture systems employed. None produced detectable levels of interferon, and responsiveness of the cells to induction of interferon by virus remained unaltered. Infection with mycoplasma did not impair the sensitivity of the cells to the action of interferon, nor was the replication of vesicular stomatitis virus noticeably diminished. PMID- 4287407 TI - The biohydrogenation of alpha-linolenic acid and oleic acid by rumen micro organisms. AB - 1. alpha-[U-(14)C]Linolenic acid was incubated with the rumen contents of sheep and the metabolic products were characterized by thin-layer chromatography, gas liquid chromatography and absorption spectroscopy in the ultraviolet and infrared. 2. A tentative scheme for the biohydrogenation route to stearic acid is presented. The main pathway is through diconjugated cis-cis-cis-octadecatrienoic acid, non-conjugated trans-cis (cis-trans)-octadecadienoic acid and trans octadecenoic acid, but other pathways are apparent. 3. Washed rumen micro organisms possessed only a limited capacity to hydrogenate alpha-linolenic acid and oleic acid but the rate was greatly stimulated by a factor(s) present in the supernatant rumen liquor. 4. Pure cultures of Clostridium perfringens, Streptococcus faecalis, Escherichia coli and a coliform organism isolated from sheep faeces possessed negligible ability to hydrogenate unsaturated fatty acids compared with a mixed population of rumen micro-organisms. Butyrivibrio fibrisolvens slowly converted linoleic acid into octadecenoic acid. PMID- 4287406 TI - The chemical synthesis and biological oxidation of 7-alpha-hydroxy[26 14C]cholesterol, 7-dehydro[26-14C]cholesterol and 26-hydroxy[26-14C]cholesterol. AB - 1. 26-Hydroxycholesterol was obtained by reducing the methyl ester of (+/-)-3beta hydroxycholest-5-en-26-oic acid, which was synthesized from 25-oxonorcholesterol. 2. Methods for preparing 7alpha-hydroxycholesterol and 7-dehydrocholesterol were modified to allow the micro-scale preparation of these [(14)C]sterols from [26 (14)C]-cholesterol. 3. 26-Hydroxycholesterol was oxidized more readily than 7alpha-hydroxycholesterol, 7-dehydrocholesterol or cholesterol by mitochondrial preparations from livers of mice, rats, guinea pigs, common toads (Bufo vulgaris) and Caiman crocodylus. 4. (+/-)-3beta-Hydroxy[26-(14)C]cholest-5-en-26-oic acid was oxidized very rapidly to (14)CO(2) by mouse and guinea-pig mitochondria without evident discrimination between the two optical isomers. 5. An enzyme system that oxidizes 26-hydroxycholesterol to 3beta-hydroxycholest-5-en-26-oic acid was identified in the soluble extract of rat-liver mitochondria. This enzyme could use NADP in place of NAD but was not identical with liver alcohol dehydrogenase (EC 1.1.1.1). 6. [26-(14)C]Cholesteryl 3beta-sulphate was not oxidized by fortified mouse-liver preparations that oxidized [26 (14)C]cholesterol to (14)CO(2). PMID- 4287408 TI - Effects of prolonged incubation of isolated fat cells on their response to hormones stimulating lipolysis and glucose metabolism. AB - 1. The metabolism of isolated fat cells from parametrial adipose tissue of starved normal rats was studied during 8hr. incubation. 2. There was a three- to eight-fold increase in conversion of glucose into carbon dioxide, fatty acids and glycerol during the fourth to eighth hours of incubation in 4% albumin buffer over that seen during the first 4hr. of incubation. 3. The addition of growth hormone and dexamethasone to fat cells at the start of the incubation period accelerated lipolysis during the first 4hr. of incubation but no further effect was seen during the fourth to eighth hours of incubation. Addition of growth hormone and dexamethasone to fat cells that had been incubated for 4hr. did not accelerate lipolysis during the next 4hr. whether fat cells were incubated with or without glucose. 4. Fat cells incubated for prolonged periods also displayed a reduced sensitivity to the lipolytic action of adrenocorticotrophic hormone. 5. During prolonged incubation there was no damage to the cells as judged by the retention of two soluble cytoplasmic enzymes, lactate dehydrogenase and malate dehydrogenase, within the cells. PMID- 4287410 TI - Effects of phenfromin and hypoglycin on gluconeogenesis of rat tissues. PMID- 4287409 TI - Factors influencing the utilization of reduced nicotinamide adenine dinucleotide by pigeon heart mitochondria. PMID- 4287411 TI - The role of magnesium in the oxidation of external reduced nicotinamide adenine dinucleotide by rat liver mitochondria. PMID- 4287412 TI - Aldosterone and corticosterone production by rat adrenal slices as a function of the time of incubation. PMID- 4287413 TI - Accumulation of guanine nucleotides in the acid-soluble fraction of Bacillus subtilis inhibited by actinomycin D. PMID- 4287414 TI - Spontaneous tumours in rats and mice. PMID- 4287415 TI - [Complex-chemical behavior of pyrimidine derivatives. V. Complex formation of some pyrimidine derivatives with copper(II) perchlorate]. PMID- 4287416 TI - Histological studies of cortisone and A.C.T.H. treated rabbits after fracture. PMID- 4287417 TI - Biochemical changes in the endoplasmic reticulum in liver injury. PMID- 4287418 TI - Direct intracardiac extension of a carcinoma of the caecum. PMID- 4287419 TI - A benign giant-cell synovioma in a cat. PMID- 4287420 TI - Demonstration of the Golgi apparatus in cells in tissue culture. PMID- 4287421 TI - Further isolations of reovirus type 3 from cases of Burkitt's lymphoma. PMID- 4287422 TI - Case of encephalitis due to herpes simplex. PMID- 4287423 TI - [Study of some physico-chemical properties of the bovine papillomatosis virus]. PMID- 4287425 TI - A study of skeletal maturation of hand and wrist and its relationship to nutrition. PMID- 4287424 TI - Effects of cortisol implants in the brainstem and ventral hippocampus on diurnal corticosteroid levels. PMID- 4287426 TI - [Clinico-radiographic tests of the new, soluble in water, tri-iodized contrast medium Uromiro]. PMID- 4287428 TI - [Lyell's syndrome. (Description of a case)]. PMID- 4287427 TI - [A new purified ACTH in the treatment of asthma. Clinical study]. PMID- 4287429 TI - [Genetic characteristics of attenuated foot-and-mouth-disease (FMD) viruses. The virus increase at 40, 37, 28 and 22 degrees C in tissue cultures]. PMID- 4287430 TI - [Studies on the dermotoxins of the 6 Clostridium welchii types in rabbits]. PMID- 4287432 TI - [Ascites, edema and left hypogastric pain]. PMID- 4287433 TI - [Case of aveolar carcinoma of the lung]. PMID- 4287431 TI - The effect of acute haemorrhage in the dog and man on plasma-renin concentration. AB - 1. The effect of acute haemorrhage on the plasma renin concentration was studied in the dog and man.2. Plasma-renin concentration was regularly increased after the larger bleeds; after the smaller haemorrhages plasma-renin concentration remained unchanged.3. The results are discussed in relation to current hypotheses concerning the control of renin and aldosterone secretion. PMID- 4287434 TI - Hematologic phagocytosis in postmortem bone marrows of dengue hemorrhagic fever. (Hematologic phagocytosis in Thai hemorrhagic fever). PMID- 4287435 TI - [Immunoelectrophoresis of perchloric acid-soluble serum proteins]. PMID- 4287436 TI - [Simultaneous action of alpha-radiation and silicon dioxide in experimental animals. II]. PMID- 4287437 TI - [Elimination of cast steel cleaning dust from the lungs of exposed rats]. PMID- 4287438 TI - [Indications and contraindications of the penicillin-streptomycin combination in acute pulmonary diseases]. PMID- 4287440 TI - [Unusual outbreak of epidemic keratoconjunctivitis due to adenovirus type 8]. PMID- 4287439 TI - The myocardial succino-oxidase and myosin adenosine triphosphatase activities after coronary arterial infusion of histamine in dogs. PMID- 4287441 TI - [Identification of animal strains of Clostridium welchii by the agglutination test. 4. Types C and F]. PMID- 4287442 TI - [The significance of bacterial adjuvants for the development of susceptibility to anaphylactic shock in mice and rats. I. The increase of anaphylactic sensitivity and serum antibody formation by bacteria and bacteria-containing substances in mice and rats]. PMID- 4287444 TI - Respiratory activity of isolated mammalian nuclei. 3. The reduced nicotinamide adenine dinucleotide oxidase of rat liver nuclei and nucleoli. PMID- 4287443 TI - [Reversible inhibition of the reproduction of virus SV-40 by aromatic alcohols]. PMID- 4287445 TI - Chicken gizzard myosin. PMID- 4287446 TI - Phosphorolysis of adenosine diphosphoribose. PMID- 4287447 TI - Glycine reduction to acetate and ammonia: identification of ferredoxin and another low molecular weight acidic protein as components of the reductase system. PMID- 4287448 TI - Demonstration of pancreatic insulomas by angiography. PMID- 4287449 TI - Failure to diagnose Zollinger-Ellison syndrome by pancreatic arteriography. Report of a case. PMID- 4287450 TI - Lymphangiography and endolymphatic radiotherapy in testicular tumours. PMID- 4287451 TI - Observations on the surgical interruption of lymphatic pathways. PMID- 4287452 TI - Effect of cellular disruption on certain metabolic activities in Vibrio cholerae. PMID- 4287453 TI - Granulomatous reactions induced by silica. I. Relationships between particles size and multinucleated giant cells. PMID- 4287454 TI - [Intragluteal medicinal conglomerate]. PMID- 4287455 TI - [On the knowledge of laryngeal chemodectomas]. PMID- 4287456 TI - Co-ordination chemistry and membrane function with particular reference to the synapse and catecholamine transport. PMID- 4287458 TI - Bronchiolar apocrine tumor. PMID- 4287457 TI - [Histochemical investigations on the behavior of some enzymes in the adrenal glands in guinea pigs following chronic noise influence]. PMID- 4287459 TI - [Multiple cutaneous Abrikossof tumors]. PMID- 4287460 TI - [Electron spin resonance and infrared spectrum of triterpenoids isolated from ginseng]. PMID- 4287461 TI - [Ultrarapid stimulation of the enzymatic activity in fertilization processes]. PMID- 4287462 TI - [Therapeutical trials of a new combination of antibiotic and cortisone-like agents in cutaneous disinfections, leg wounds and ulcers]. PMID- 4287463 TI - [Ectopic carcinoid of the bronchus]. PMID- 4287464 TI - [Silicon metabolism in microorganisms. VI. Enzymatic changes of metabolism in the conversion of phosphate to silicate in Proteus mirabilis]. PMID- 4287465 TI - Purification of a non-heme iron protein and other electron transport components from Azotobacter extracts. PMID- 4287466 TI - Nitrogen base inhibition of yeast alcohol dehydrogenase. PMID- 4287467 TI - Intracellular distribution of cathepsin B and cathepsin C in rat liver. PMID- 4287468 TI - Selective hydrolysis of rat-liver lecithin by phospholipase C. PMID- 4287469 TI - [On the function of the anterior pituitary lobe in meningitis studies with the metopirone test]. PMID- 4287470 TI - Virus dispersal by water. PMID- 4287471 TI - Influence of ACTH on convulsive activity in children. Electroencephalographic and clinical observations. PMID- 4287472 TI - Amino acid and vitamin requirements of Bordetella pertussis. PMID- 4287473 TI - Some observations on the effect of mammary tumour agent on cells cultivated in vitro. PMID- 4287474 TI - Role of thymus in viral leukemogenesis in rats. PMID- 4287475 TI - [Experimental leukemia: a study of the Rauscher virus disease in the mouse and rat]. PMID- 4287476 TI - [On neurogenic tumors of the mediastinum]. PMID- 4287477 TI - Histochemical studies of cholinesterases in Ciona intestinalis. PMID- 4287478 TI - Effects of cholinergic drugs on tunicate smooth muscle. PMID- 4287479 TI - Phospholipid patterns of Periplaneta americana during embryogenesis. PMID- 4287480 TI - [Studies on pig erythrocyte lipids. I. Fractionation of erythrocyte lipids by the simple combination of silicic acid and cellulose column chromatography]. PMID- 4287481 TI - [Hemorrhagic necrosing myelitis and perivenous encephalitis occurring at the time of a herpetic primo-infection]. PMID- 4287482 TI - Quantitative analysis of urinary 17-oxogenic steroids using sodium metaperiodate oxidation. PMID- 4287483 TI - The automated determination of NAD-coupled enzymes. II. Serum lactate dehydrogenase. PMID- 4287484 TI - An enzymatic-spectrophotometric determination of pyruvic and lactic acid in blood. Methodologic aspects. PMID- 4287485 TI - The mechanism of insulin action. The effect of insulin action. The effect of insulin on the allosteric properties on intracellular haemoglobin. AB - 1. The results in three experimental series have suggested that a number of modifying factors must be taken into account in considering the allosteric behaviour of structurally bound intracellular, as distinct from free, haemoglobin. It seems that intracellular haemoglobin maintains its maximal internal stability during oxygen uptake and release by configurational changes which involve not only its acid-base-binding groups but also partial electron transfer complexes with the stromal macro-molecular framework. Conversely, the affinity of intracellular haemoglobin for oxygen reflects the positive or negative electron pressures prevailing at the haemoglobin-stromal complexing sites.2. Active glucolysis in intact cells entails continuous poising of metabolic redox potential changes by the stromal material (in the same way as it entails continuous buffering of acid metabolic products). The consequent shifts in stromal redox potential and capacity are transmitted to haemoglobin and are reflected in a changing affinity for oxygen.3. The behaviour of the intracellular haemoglobin-stromal complex is further modified by extracellular electron donors and acceptors and by the capacity of the cell/extracellular interface to act as an electrochemical barrier between them. It is probably the last variable which is directly influenced by insulin.4. Two parameters have been introduced as empirical measures of the distinctive allosteric properties of cell-bound haemoglobin: (i) D-pH to represent the apparent cell/extracellular pH gradient; and (ii) D-O(2) to represent the volume of oxygen evolved when cells are lysed at a constant P(O2). Under a variety of experimental conditions insulin affected both these parameters.5. The insulin effects were consistent with a concept which rests on three main contentions. (i) Insulin has an immediate physical action on the cell/extracellular interface, altering the redox potential gradient (electron conductance) across the plasma membrane. (ii) Conversely, the formation of an insulin-membrane complex depends, among other factors, on the prevailing trans membrane redox potential difference. (iii) The consequences of insulin-membrane interaction are both immediate and sustained, and, under appropriate conditions, they are reflected in the affinity of intracellular haemoglobin for oxygen.6. At a more general level it has been shown that in many respects haemoglobin behaves as a built-in intracellular redox indicator dye. Like most synthetic redox indicators, it is pH dependent. PMID- 4287487 TI - [On alveolar carcinoma of the lung]. PMID- 4287486 TI - [Demonstration of a low-molecular glycoprotein in neoplasms and the characterization of its chemical peculiarities]. PMID- 4287488 TI - Studies of adenovirus-SV40 hybrid viruses. IV. An adenovirus type 2 strain carrying the infectious SV40 genome. PMID- 4287489 TI - Determining factor in the capacity of Rous sarcoma virus to induce tumors in mammals. PMID- 4287491 TI - [Most frequent clinical forms of adenovirus infections in children]. PMID- 4287490 TI - Mutants of bacteriophage T4 unable to cause breakdown of host DNA. PMID- 4287492 TI - Biological polymers related to catechol: electron paramagnetic resonance and infrared studies of melanin, tannin, lignin, humic acid and hydroxyquinones. PMID- 4287493 TI - Studies on polynucleotides. LIV. A further study of the reaction of nucleotide pyrophosphates with carboxylic acid anhydrides. PMID- 4287494 TI - Genetic and non-genetic factors in chromatographic behaviour of poliovirus. PMID- 4287495 TI - Protective effect of neonatal thymectomy on cystic disease induced in rats by Rous sarcoma virus. PMID- 4287496 TI - Stereospecificity of certain soluble and particulate preparations of mitochondrial reduced nicotinamide-adenine dinucleotide dehydrogenase from beef heart. PMID- 4287497 TI - Stimulation of steroid C-11-beta-hydroxylation in adrenal mitochondria by cyclic 3',5'-adenosine monophosphate. PMID- 4287498 TI - [Carbon monoxide coma. General, clinical, biological and therapeutic study of 290 cases]. PMID- 4287499 TI - [Pulmonary ultrastructure]. PMID- 4287500 TI - Carcinoma of the ovary. A clinicopathological study of 86 autopsied cases with special reference to mode of spread. PMID- 4287501 TI - Prevalence of enterovirus infection among healthy young children in Taipei area. PMID- 4287502 TI - Granular cell tumors (myoblastomas) of the tracheobronchial tree. PMID- 4287503 TI - Effect of vitamins in single dose on liver of mice on prolonged ethanol intake. PMID- 4287504 TI - [The effect of chronic hypoglycemia on the status of the islands of Langerhans in the rat]. PMID- 4287505 TI - [The effect of gonadectomy, androgens, and estrogens on some histochemical reactions in the seminal vesicles of the rat]. PMID- 4287506 TI - [Resistance of the tuberculosis bacillus to ethionamide, cycloserine, and viomycin noting coexistant resistance to streptomycin, isonicotinic acid, and para-aminosalicylic acid]. PMID- 4287507 TI - [Ovarian hilus cell tumor associated with virilization: report of a case and review of the literature]. PMID- 4287508 TI - Effect of estrogens on blood clotting and plasmin systems. PMID- 4287509 TI - [Results obtained in 6 cases of tumors treated with sarkomycin (an antitumoral antibiotic)]. PMID- 4287511 TI - The effects of aldosterone and angiotensin on renal function. PMID- 4287510 TI - [Detection of dephosphorylation enzymes in rat and mouse ova fixed in formalin and treated in toto]. PMID- 4287512 TI - Variations of tensile strength of human cortical bone with age. PMID- 4287513 TI - The direct renal action of angiotensin in the rabbit. PMID- 4287514 TI - Relationship of plasma volume changes to resistance and capacitance vessel effects of sympathomimetic amines and angiotensin in man. PMID- 4287515 TI - Susceptibility of turkey-poults to two avian leucosis strains. PMID- 4287516 TI - Electron-microscope proof of virus particles in fowl myelocytomatosis. PMID- 4287517 TI - Paralysis of the peroneal nerve in association with a plantar flexion inversion injury of the ankle. PMID- 4287518 TI - [Glioblastoma multiforme]. PMID- 4287519 TI - [The experimental disinfection of the vaccine virus as the basis for the clinical smallpox disinfection]. PMID- 4287520 TI - [The canalicular origin of certain painful syndromes of the upper limb]. PMID- 4287521 TI - An improved method for the radioisotopic labeling of poliovirus and vaccinia virus. SAM-TR-66-29. PMID- 4287522 TI - [Changes in the sulfhydryl and disulfide level in blood serum in various pigment disorders of the skin]. PMID- 4287523 TI - Oxidation of malate by Mycobacterium phlei extracts. PMID- 4287524 TI - [Cerebral tumor in pregnancy]. PMID- 4287525 TI - Hepatoma induced by thorium dioxide (thorotrast). AB - A case of hepatoma induced by thorium dioxide (Thorotrast) is reported. The literature concerning neoplasia associated with this agent is reviewed, with emphasis on the long latent period before the development of these tumours and the equally long latent period which preceded the recognition of their iatrogenic nature.In particular, this report is intended to illustrate the diagnosis of such tumours on radiological and histological findings, provided that one is aware of their existence and familiar with the distribution and appearance of thorium dioxide deposits in the tissues. Such a diagnosis can be made without a history of thorium dioxide administration, which often may not be available. PMID- 4287526 TI - [Results of viomycin therapy of tuberculosis in children]. PMID- 4287528 TI - [Alveolar cell carcinoma]. PMID- 4287527 TI - [Hepatic coma as a final manifestation of severe generalized hypersensitivity to streptomycin, cycloserin and ACTH]. PMID- 4287529 TI - Inquiries into the myocardial enzyme activity in experimental myocarditis. PMID- 4287530 TI - Histochemical inquiries into the conduction system of the heart in some hoofed animals. PMID- 4287531 TI - Separation of 3-alpha- and 3-beta-hydroxysteroid oxidoreductases from the soluble fraction of rat liver by gel filtration. PMID- 4287532 TI - [The nephrotic syndrome, clinical features and therapy]. PMID- 4287533 TI - [On the determination of naphthol-AS-D-chloracetate-esterase in histiocytomas of the skin]. PMID- 4287534 TI - [A contribution to the paraganglionic character of glomus tumors in the neck and head regions]. PMID- 4287535 TI - Comparison of anaesthesia with innovar, halothane and methoxyflurane-nitrous oxide. PMID- 4287536 TI - The influence of endoxan, hydrocortisone and antistine on the metabolism of cells cultured in vitro. PMID- 4287537 TI - Islet cell tumors. Case report. PMID- 4287538 TI - The behavior of thiamine pyrophosphatase, acid phosphatase and NADA-2-tetrazolium reductase in the spinal cord of mice intoxicated with benzene. PMID- 4287539 TI - [Aren't the "whooping-coughs" of vaccinated children often "para-whooping coughs"? 2 cases with bacteriologic identification of parapertussis bacillus]. PMID- 4287540 TI - Adrenal blood flow response to adrenocorticotrophic hormone and other stimuli in the dog. PMID- 4287541 TI - Preparation, characterization and determination of glycogen in rat ascites hepatomas. PMID- 4287542 TI - Adenovirus complement-fixing antibody in atypical pneumonia and difference in antibody titer among adenovirus types used as antigen. PMID- 4287543 TI - [Spectrophotometric and column-chromatographic analysis of ribonucleic acid extracted from suspensions of the brains of mice infected with MM virus exposed to the action of heat]. PMID- 4287544 TI - Studies on the pleomorphism of HVJ virons. PMID- 4287545 TI - Electrophoretic separation of polyoma virus DNA from host cell DNA. PMID- 4287546 TI - The reversion of guanidine inhibition of poliovirus synthesis. PMID- 4287547 TI - Magnesium trisilicate increases virus transmission. PMID- 4287548 TI - [Possibilities of virological diagnosis in infectious hepatitis (H.i.)]. PMID- 4287549 TI - Some aspects of myasthenia gravis. PMID- 4287550 TI - Treatment of severe myasthenia gravis with large doses of ACTH. PMID- 4287551 TI - Cytochrome oxidase and its derivatives. VI. The CO combining capacity of cytochrome C oxidase. PMID- 4287552 TI - Experimental studies on bacteriocinogeneity in Clostridium perfringens type A. I. Isolation of bacteriocines and their antibacterial spectrum. PMID- 4287553 TI - Respiratory chain and phosphorylation site of the sonicated membrane fragments of Micrococcus lysodeikticus. PMID- 4287554 TI - Purification and properties of a pyrophosphatase from rat liver microsomes capable of catalyzing the hydrolysis of UDP-glucuronic acid. PMID- 4287555 TI - Lipid of cancer tissues. I. Lipid composition of Shionogi carcinoma 115 and Nakahara-Fukuoka sarcoma. PMID- 4287556 TI - Reproduction of the viruses isolated from cases of infectious hepatitis on Detroit-6(VA) cell line. PMID- 4287557 TI - [On the duration and conditions of survival in a group of subjects operated on for glioblastoma multiforme]. PMID- 4287558 TI - On the ligand field of iron in ferredoxin from spinach chloroplasts and related nonheme iron enzymes. PMID- 4287559 TI - Angiofibroma of the nasopharynx. PMID- 4287560 TI - [On glomangioma of the stomach]. PMID- 4287561 TI - [Giant inflammatory tumors in the otorhinolaryngological field]. PMID- 4287562 TI - [Beta-angiotensin. II. Experimental study]. PMID- 4287563 TI - [The significance of bacterial adjuvants for the development of susceptibility to anaphylactic shock in mice and rats. II. Suppression of susceptibility to anaphylactic shock in mice and rats]. PMID- 4287565 TI - Action of proflavine on the development of Sendai virus in HEp 2 cells. PMID- 4287564 TI - Local complications of thiopentone injection. PMID- 4287566 TI - Thiosemicarbazone-resistant rabbitpox virus. PMID- 4287567 TI - Fate of intravenously administered interferon and the distribution of interferon during virus infections in mice. PMID- 4287568 TI - An enzymatic fluorometric micromethod for the determination of glycerol. PMID- 4287569 TI - Effects of dilute acids on the chemical and immunochemical properties of human orosomucoid. PMID- 4287570 TI - [Determination of sterols in rats after treatment with delta-7 and delta-24 reductase inhibitors]. PMID- 4287571 TI - Clinical notes on feline respiratory viral disease. PMID- 4287572 TI - [Case of Paget's disease with early lung metastasis]. PMID- 4287573 TI - [Personal injuries caused by lightning]. PMID- 4287574 TI - [On the clinical aspects and treatment of traumatic lesions of the peripheral nerves in children]. PMID- 4287575 TI - [Rheumatic lesion of the peripheral nervous system in children]. PMID- 4287576 TI - Theoretical dental technology for apprentices' refractory materials. PMID- 4287577 TI - Granular cell myoblastoma of the tongue: report of case. PMID- 4287578 TI - Protein synthesis by cell-free extracts of Crithidia oncopelti. PMID- 4287580 TI - [Pathology of renal tumors]. PMID- 4287579 TI - Studies on the oxidative metabolism of Moniliformis dubius (Acanthocephala). PMID- 4287582 TI - Production of interferon by alveolar macrophages. AB - Acton, Jean D. (Bowman Gray School of Medicine, Winston-Salem, N.C.), and Quentin N. Myrvik. Production of interferon by alveolar macrophages. J. Bacteriol. 91:2300-2304. 1966.-Rabbit alveolar macrophages inoculated with parainfluenza-3 virus in vitro produce a viral inhibitor which possesses the properties of interferon. The interferon is nondialyzable, is stable at pH 4, is not sedimented at 100,000 x g, exhibits species specificity, and can passively protect other alveolar macrophages from infection with virulent rabbitpox virus. The possible significance of alveolar macrophage-produced interferon is discussed. PMID- 4287581 TI - Antigens of Bordetella pertussis. IV. Effect of heat, merthiolate, and formaldehyde on histamine-sensitizing factor and protective activity of soluble extracts from Bordetella pertussi.s. AB - Munoz, J. (Rocky Mountain Laboratory, Hamilton, Mont.), and B. M. Hestekin. Antigens of Bordetella pertussis. IV. Effect of heat, Merthiolate, and formaldehyde on histamine-sensitizing factor and protective activity of soluble extracts from Bordetella pertussis. J. Bacteriol. 91:2175-2179. 1966.-Both histamine-sensitizing and protective activities of soluble preparations from Bordetella pertussis cells are destroyed by heating at 80 C for 0.5 hr. The histamine-sensitizing activity appeared to be more susceptible to inactivation by heat than the protective activity. Formaldehyde in a final concentration of 0.5% rapidly diminished the histamine-sensitizing ability of saline extract (SE) held at 37 C. The protective activity was clearly more resistant to inactivation by formaldehyde at similar temperature. The inactivating action of formaldehyde was slower when the concentration of SE was increased or when the mixture was kept at 2 to 5 C. Merthiolate in a final concentration of 1:10,000 had no demonstrable deleterious effects on either protective or histamine-sensitizing activity of SE. PMID- 4287583 TI - Urea and thermal mutants of poliovirus. AB - Hallum, J. V. (University of Pittsburgh, Pittsburgh, Pa.), and J. S. Youngner. Urea and thermal mutants of poliovirus. J. Bacteriol. 91:2305-2308. 1966. Thermally selected mutants of poliovirus which differed in sensitivity to heating at 50 C were inactivated with urea. With 3 m urea, urea resistance paralleled thermal resistance. In contrast, when urea-resistant mutants were selected from thermosensitive, urea-sensitive, wild-type poliovirus, the 50 C sensitivity of the selected mutants did not change. These findings indicate a lack of covariance of the urea and the 50 C-inactivation markers of poliovirus. PMID- 4287584 TI - Differential inhibitory effects of actinomycin D among strains of poliovirus. AB - Schaffer, Frederick L. (University of California, Berkeley), and Marjorie Gordon. Differential inhibitory effects of actinomycin D among strains of poliovirus. J. Bacteriol. 91:2309-2316. 1966.-Actinomycin D exerted a differential effect on the ability of strains of poliovirus to replicate in HeLa cells. LSc-2ab was studied as an example of a strain markedly inhibited by actinomycin; MEF(1) served as a control strain with minimal inhibition. The effect was noted at an actinomycin concentration of 0.1 mug/ml, but 2.5 mug/ml was used for most studies. Variability in the effect was attributed, in part, to physiological factors. Actinomycin was effective when present during the first 2 hr of LSc infection, but had little effect if present at later times. It did not block adsorption or initiation of ecilpse. It did block synthesis of ribonucleic acid in LSc-infected cells. Several possible modes of action are discussed, the most attractive being that actinomycin blocks synthesis of some cell component, the concentration of which is more critical for replication of some poliovirus strains than others. PMID- 4287585 TI - Replication of mengovirus. I. Effect on synthesis of macromolecules by host cell. AB - Plagemann, Peter G. W. (Western Reserve University, Cleveland, Ohio), and H. Earle Swim. Replication of mengovirus. I. Effect on synthesis of macromolecules by host cell. J. Bacteriol. 91:2317-2326. 1966.-The replication of mengovirus was studied in two strains of Novikoff (rat) hepatoma cells propagated in vitro. The replicative cycle in both strains required 6.5 to 7 hr. Infection resulted in a marked depression of ribonucleic acid (RNA) and protein synthesis by strain N1S1 63. Inhibition of RNA synthesis was reflected by a decrease in the deoxyribonucleic acid (DNA)-dependent RNA polymerase activity of isolated nuclei. Mengovirus had no effect on either protein or RNA synthesis or on the DNA dependent RNA polymerase activity of a second strain, N1S1-67. The time course of viral-induced synthesis of RNA by cells was studied in cells treated with actinomycin D. It was first detectable between 2.5 and 3 hr after infection and continued until 6.5 to 7 hr. The formation of mature virus was estimated biochemically by measuring the amount of RNA synthesized as a result of viral infection which was resistant to degradation by ribonuclease in the presence of deoxycholate. Approximately 70% of the deoxycholate-ribonuclease-resistant RNA was located in mature virus, and the remainder was double-stranded. The formation of mature virus began about 45 min after viral-directed (actinomycin-resistant) synthesis of RNA was detectable in the cell, and only about 18 to 20% of the total RNA synthesized was incorporated into virus. Release of virus from cells began about 1 hr after maturation was first detectable. Release of virus from cells was accompanied by a loss of a large proportion of their cytoplasmic RNA and protein. PMID- 4287586 TI - Replication of mengovirus. II. General properties of the viral-induced ribonucleic acid polymerase. AB - Plagemann, Peter G. W. (Western Reserve University, Cleveland, Ohio), and H. Earle Swim. Replication of mengovirus. II. General properties of the viral induced ribonucleic acid polymerase. J. Bacteriol. 91:2327-2332. 1966.-Mengovirus induces the appearance of a ribonucleic acid (RNA) polymerase activity in Novikoff hepatoma cells which is readily distinguished from the deoxyribonucleic acid (DNA)-dependent RNA polymerase since it is not inhibited by actinomycin D or deoxyribonuclease, but is inhibited by ammonium sulfate, and is stable at -17 C. The incorporation of uridine into RNA by infected cells in the presence of actinomycin D does not reflect the viral polymerase activity as measured in cell free preparations. The viral-induced RNA polymerase is produced in a biphasic fashion. Puromycin inhibits the production of viral polymerase, and in its presence the enzyme appears to be unstable between 4 and 6 hr. Puromycin also prevents the secondary rise in polymerase which begins at the end of replicative cycle. Under these conditions, however, the polymerase appears to be stable. The overall data indicated that some unspecified process is responsible for the apparent instability of viral-induced RNA polymerase between 4 and 6 hr and that it becomes inoperative toward the end of the replicative cycle. PMID- 4287587 TI - Presence and persistence of foot-and-mouth disease virus in bovine skin. AB - Gailiunas, Peter (Plum Island Animal Disease Laboratory, Greenport, N. Y.), and George E. Cottral. Presence and persistence of foot-and-mouth disease virus in bovine skin. J. Bacteriol. 91:2333-2338. 1966.-This study established that the seven known antigenic types of foot-and-mouth disease virus (FMDV) have consistent affinity to all areas of bovine skin, even though gross cutaneous lesions usually are found only in the pedal area. Considerable amounts of FMDV were present in skin of 13 different body areas, irrespective of the presence of hair. All skin specimens from the trunk of 50 experimentally infected steers, necropsied from 12 hr to 7 days postinoculation (DPI), contained FMDV in the dermal and epidermal tissues. In skins of some steers, FMDV persisted for as long as 5 days after cessation of viremia. The highest average virus titer, 10(3.6) plaque-forming units (PFU) per g of skin, was found at 2 DPI. Some areas of the trunk and extremities had titers of approximately 10(5.0) PFU per g of skin. Characteristic gross lesions were not observed in sampling areas. The present observations have epizootiological importance for hides offered in international trade, because FMDV localized intracutaneously is more difficult to inactivate than virus adhering to hide surfaces. PMID- 4287588 TI - Growth characteristics of two rhinovirus strains in WI-26 and monkey kidney cells. AB - Haff, R. F. (Smith Kline & French Laboratories, Philadelphia, Pa.), B. Wohlsen, E. E. Force, and R. C. Stewart. Growth characteristics of two rhinovirus strains in WI-26 and monkey kidney cells. J. Bacteriol. 91:2339-2342. 1966.-Viruses with 1059 and HGP serotype and with human and monkey host range characteristics, respectively, were employed. Adsorption kinetics of the 1059 and HGP strains to WI-26 cells, and HGP to Green African monkey kidney cells (MKC), were similar. Fifty per cent of the virus was adsorbed to cell monolayers within 10 min; adsorption was essentially complete by 2 hr. The 1059 strain failed to adsorb to MKC, at least to an appreciable extent. Lack of receptors for adsorption of 1059 accounts for the inability of this cell to support multiplication of the virus. It is probable that MKC are refractory to infection with other H strains of rhinovirus for the same reason. Single-step multiplication cycles have been described for the HGP strain in WI-26 and MKC cultures and for the 1059 strain in WI-26 cells. In both cells, HGP exhibited a latent period of 7 hr. Increase of intracellular and cell-associated virus appeared somewhat prior to that of extracellular virus. Maximal titers were attained by 9 to 10 hr. In contrast, initial increase of 1059 in WI-26 cells occurred after 10 hr. Titer rose to peak level 15 hr after infection. Yield of 1059 in WI-26 cells was also fivefold lower than that of HGP in either cell system. PMID- 4287589 TI - Inapparent viral infection of cells in vitro. 3. Manifestations of infection of L mouse cells by Japanese encephalitis virus. AB - Dubbs, D. R. (University of Minnesota, Minneapolis), and W. F. Scherer. Inapparent viral infection of cells in vitro. III. Manifestations of infection of L mouse cells by Japanese encephalitis virus. J. Bacteriol. 91:2349-2355. 1966. Nine strains of Japanese encephalitis (JE) virus were propagated serially in cultures of L cells reaching titers of 10(3.5) to 10(6.3). Although cytopathic effects were not seen in cultures of contiguous L cells after infection with JE virus, cell growth was inhibited. Moreover, cell destruction was readily apparent in infected cultures of sparse, noncontiguous L cells. Differences in the size of cell population of infected and noninfected cultures (i) occurred despite only 0.2 to 3.5% of the cells in infected cultures being associated with infectious virus, (ii) were greater in actively growing cultures than in those kept in maintenance media, and (iii) were probably in part related to an interferon produced in infected cultures. PMID- 4287591 TI - [Studies on biological properties of whole cells and cellular components of an avirulent strain of Bordetella pertussis]. PMID- 4287590 TI - [Survival of Bordetella pertussis in the air and on some objects]. PMID- 4287592 TI - [The effect of 5-hydroxytryptamine on adrenocortical function of rats]. PMID- 4287593 TI - Granular cell myoblastoma of the vermiform appendix. PMID- 4287594 TI - [Anterior pituitary hormones]. PMID- 4287595 TI - [Emaciation and hormones]. PMID- 4287596 TI - [Oral cylindroma]. PMID- 4287597 TI - [Clinical study on ACTH in the urine]. PMID- 4287598 TI - [Adrenocortical tumor]. PMID- 4287599 TI - [Insuloma; on endocrine function]. PMID- 4287600 TI - [Endocrine disorders in lung cancer]. PMID- 4287601 TI - [Paraneoplastic syndromes in hepatoma with special reference to hormone-producing hepatoma]. PMID- 4287602 TI - Sudden unexpected death in infancy and viral infection. PMID- 4287603 TI - [Ultrastructural lesions of the liver in subacute alcoholic hepatitis and cirrhogenous alcoholic hepatitis]. PMID- 4287604 TI - [Contribution of biological tests in the preoperative diagnosis of common bile duct calculi. Their comparison with clinical data and other paraclinical tests: radiology, laparoscopy, histology]. PMID- 4287605 TI - [Critical study of icterus caused by chlorpromazine]. PMID- 4287606 TI - [Hypoglycemic langerhansian adenoma. Current means of investigation apropos of a case of J. Hepp and H. P. Klotz]. PMID- 4287607 TI - [Immunotherapy of advanced cancers. Practical methods and short-term results. Preliminary note apropos of 16 cases]. PMID- 4287608 TI - [Prolonged polychemotherapy of inoperable bronchopulmonary cancers. Apropos of 165 cases]. PMID- 4287609 TI - Effects of norethandrolone on cortisone-induced pitiutary-adrenal suppression in the rat. PMID- 4287610 TI - [Abrikosov's tumor of the larynx]. PMID- 4287611 TI - [Syndrome of reminization in a postmenopausal woman due to feminizing teca-cell tumour of the ovary]. PMID- 4287612 TI - [Levels of testosterone in blood plasma of healthy and sick men and women]. PMID- 4287613 TI - Effect of niamid and benzquinamide (Quantril) on the release of corticotrophin in the rat. PMID- 4287614 TI - Studies on potassium dependent phosphatase; its distribution and properties. PMID- 4287615 TI - Semiquinoid flavins adsorbed on Florisil. PMID- 4287616 TI - Crystal-induced inflammation in canine joints. I. An experimental model with quantification of the host response. AB - Injection of sodium urate or calcium pyrophosphate crystals into the stifle joints of anesthetized dogs almost invariably induced an acute exudative response. This response was quantified by serial measurements of intra-articular pressure, pH and leukocyte concentration. Pressure rose progressively and reflected intra-articular volume increase. The hydrogen ion concentration increased as the reaction progressed and correlated in a given exudate with the leukocyte concentration. Analysis of sequential physiologic and biochemical changes occurring in this model of crystal-induced inflammation may provide insight into the mechanisms of acute gouty arthritis in man. PMID- 4287618 TI - Infectious diseases, today and tomorrow. PMID- 4287617 TI - Effects of melatonin and related compounds on the release of glycerol from rat adipose tissue in vitro. PMID- 4287619 TI - [A rapid method of dynamic testing of the adrenals: the test using beta-1-24 corticotropin (Ciba 30 920-B)]. PMID- 4287620 TI - Retroperitoneal chemodectoma. PMID- 4287621 TI - Interrelations between glucose loading and glucose-6-phosphatase activity in liver of normal and alloxan-diabetic dogs. PMID- 4287622 TI - Influence of age on induction with urethan of hepatomas and other tumors in infant mice. PMID- 4287623 TI - Tumor induction in transplanted tooth buds infected with polyoma virus. PMID- 4287624 TI - [Value of the terramycin-polymyxin B combination (Primyxin) in the practice of an emergency department]. PMID- 4287625 TI - [Immunologic reaction of Bordetella pertussis and leukocytic reaction in mice]. PMID- 4287626 TI - [Research on some virological and serological aspects of respiratory infections]. PMID- 4287627 TI - [Some observations on the advantages of the osmium-zinc iodide method (Maillet's modification) for the demonstration of structures of the peripheral nervous system]. PMID- 4287628 TI - [Value of the colimycin-polymyxin B combination in the treatment and prevention of gastroenteritis due to Escherichia coli in infants]. PMID- 4287629 TI - Rhabdomyoma, a rare, benign neoplasm of skeletal muscle. PMID- 4287630 TI - [Silicon metabolism in microorganisms. VII. Distribution of silicic acid in cell fractions of Proteus mirabilis and the demonstration of carbohydrate silicic acid esters]. PMID- 4287631 TI - Quantitative precipitation of various 3-beta-hydroxysterols with digitonin. PMID- 4287632 TI - Serological and biological studies on porcine enteroviruses isolated in Canada. PMID- 4287633 TI - Minerals and the ruminant with special reference to the discovery of swayback in the goat. PMID- 4287635 TI - [Case of primary aldosteronism]. PMID- 4287634 TI - [Case of thrombotic thrombopenic purpura associated wit cholangiocellular carcinoma]. PMID- 4287636 TI - [Interferon production by chick embryo cells infected with Japanese encephalitis virus]. PMID- 4287637 TI - Melanocyte-stimulating hormone activity of synthetic MSH and ACTH peptides, in vivo and in vitro. PMID- 4287638 TI - [Attempt of explaining the seasonal occurrence of herpetic gingovostomatitis in connection with meteorological conditions]. PMID- 4287639 TI - [Enterogenous cyst of the esophagus]. PMID- 4287640 TI - On the cellular site of corticotrophin production. PMID- 4287641 TI - Serotypic relationships among rhinoviruses. PMID- 4287642 TI - Accumulation and elimination of poliovirus by the eastern oyster. PMID- 4287643 TI - Filter paper disc method of collecting whole blood for serologic studies in children. PMID- 4287644 TI - Viruses and disease: studies in a children's home. PMID- 4287645 TI - Lactic acid racemization in Cl. butylicum: 18O exchange studies. PMID- 4287646 TI - Interaction of heme A and polylysine. PMID- 4287647 TI - Unusual kinetic properties of a DPN-linked lactate dehydrogenase from Butyribacterium rettgeri. PMID- 4287648 TI - Chemistry of micrococcin P. X. Proton magnetic resonance spectrum of dimethyl micrococcinate, and the probable mode of biosynthesis of micrococcinic acid. PMID- 4287649 TI - Masculinizing lipoid cell tumor of the ovary. Report of a case. PMID- 4287650 TI - Adenoid-basal carcinoma of the cervix. PMID- 4287651 TI - Plasma 17-hydroxycorticosteroid patterns; tends in toxemia. PMID- 4287652 TI - Carcinogenic effect of N-hydroxy-N-2-fluorenylacetamide, 2',4' dimethylacetanilide, and 2',4'6'-trimethylacetanilide on liver in suckling mice. PMID- 4287653 TI - Purification and biophysical properties of rhinoviruses. PMID- 4287654 TI - Cyclic fluctuations in I-131 content of thyroid glands of cats and monkeys. PMID- 4287655 TI - Occurrence of adenovirus-SV40 hybrids among monkey kidney cell adapted strains of adenovirus. PMID- 4287656 TI - Gradient plate technique applied to the study of antiviral substances. PMID- 4287657 TI - Influence of the pituitary-adrenal axis on development of the rat foetal thymus. PMID- 4287658 TI - Inhibitory effect of ACTH and related peptides on extinction of conditioned avoidance behavior in rats. PMID- 4287659 TI - Interferon production by human leucocytes in vitro. Reduced levels in lymphatic leukemia. PMID- 4287660 TI - Transplantation of pituitary "mammotropic" tumor (MtT.F4) from Fisher to Sprague Dawley rats. PMID- 4287661 TI - Effect of p-hydroxypropiophenone on fibrosis induced by carbon tetrachloride in mice. PMID- 4287662 TI - Cytomegalovirus infection. Viral ultrastructure with particular reference to the relationship of lysosomes to cytoplasmic inclusions. PMID- 4287663 TI - Mitochondrial particles resolved for ion translocation. I. Preparation and properties of a particle coupled only at phosphorylation site 3 of the electron transfer chain. PMID- 4287664 TI - The restoration of DPNH oxidase activity by coenzyme Q (ubiquinone). PMID- 4287665 TI - Phosphorylated intermediates of terpene biosynthesis in Pinus radiata. PMID- 4287666 TI - NADH oxidase system of Agrobacterium tumefaciens. PMID- 4287668 TI - The adsorption of metal from HF-HC10-4 mixtures on some ion exchange papers. PMID- 4287667 TI - Effect of growth hormone on enzyme activities in the hypophysectomized rat. PMID- 4287669 TI - Modified anterior tibial compartment syndrome. PMID- 4287670 TI - Intrauterine contraceptive device and ovarian thecoma. PMID- 4287671 TI - Biochemical studies in a patient with hyperinsulinism. PMID- 4287672 TI - [Epidemiologic and clinical aspects of pertussis-like diseases caused by Bordetella parapertussis]. PMID- 4287673 TI - [Dynamics of changes in the oxidation-reduction potential (rH2) and morphology of Cl. perfringens cultures in the course of toxin formation on semisynthetic culture medium]. PMID- 4287674 TI - [Primary hepatoma in children: report of 6 cases]. PMID- 4287675 TI - Changes in the carotid pulse which occur with age and hypertension. PMID- 4287676 TI - On the theory of silicosis. I. Coesite. PMID- 4287677 TI - Corneal xanthomas in childhood. PMID- 4287678 TI - [Attempted stabilization of murine hepatitis virus 3 by means of lyophilization]. PMID- 4287679 TI - Mixed tumours of the submandibular gland. PMID- 4287680 TI - Cylindroma of external ear. PMID- 4287681 TI - [Study of glucose-6-phosphatase and acid phosphatase activities of the liver in mice]. PMID- 4287682 TI - [Experience with the estimation of renin activity in plasma]. PMID- 4287683 TI - [Estimation of plasma angiotensinase activity]. PMID- 4287684 TI - Electron microscopic and histochemical studies on vacuolar alteration of proximal convoluted tubules of rat kidney after hypertonic sucrose administration. PMID- 4287685 TI - Alveolar clearance: its relation to lesions of the respiratory bronchiole. PMID- 4287686 TI - [The clinical picture of adenovirus infections--a contribution to the problem]. PMID- 4287687 TI - Prevention of indwelling urinary catheter infections. PMID- 4287688 TI - [Significance of contrast lymphography in the diagnosis of lymphatic metastases]. PMID- 4287689 TI - Comparative study of experimental atherosclerosis production in white rats. PMID- 4287690 TI - Respiration and oxidative phosphorylation of mitochondria in regenerating liver of rats. PMID- 4287691 TI - Mechanism of increase in respiration intensity during embryonic development of fish. PMID- 4287692 TI - Cell strains obtained from tumors induced by SV40 virus. PMID- 4287693 TI - Fractionation of Japanese encephalitis virus by column chromatography with calcium phosphate. PMID- 4287694 TI - Electrophysiological bracing in a radial nerve compression injury. PMID- 4287695 TI - Bronchogenic carcinoma and the peripheral neuromyopathies. PMID- 4287696 TI - Lack of relationship between infection with avian leukosis virus and the presence of COFAL antigen in chick embryos. PMID- 4287697 TI - Impairment of EMC viral infectivity by cell-associated ribonuclease. PMID- 4287698 TI - The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. I. Establishment of interference. PMID- 4287699 TI - The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. II. Early steps of infection by RSV of cells under conditions of interference. PMID- 4287700 TI - Structural components of vesicular stomatitis virus. PMID- 4287701 TI - Presence of particles with the morphology of viruses of the avian leukosis complex in meningeal tumors induced in dogs by Rous sarcoma virus. PMID- 4287702 TI - [On bacteriological diagnosis of whooping cough on a coal-casein culture medium]. PMID- 4287703 TI - Cytomegaly in a 76-year old man with chronic lymphatic leukemia. PMID- 4287704 TI - The problem of malignancy of the carotid body and similar structures. PMID- 4287705 TI - Reproduction of Rous virus in mouse embryonic tissue in vitro. PMID- 4287706 TI - Effect of iron deficiency on the gastrointestinal tract of the rat. PMID- 4287707 TI - The influence of deuterium oxide and organic solvents on the interaction of respiratory chain components. PMID- 4287708 TI - Inhibition of glutamic dehydrogenase by N-1-alkylnicotinamide chlorides. PMID- 4287709 TI - Electron transport systems of yeast. 3. Preparation and properties of cytochrome oxidase. PMID- 4287710 TI - Phosphotransferase activities of kidney glucose 6-phosphatase. PMID- 4287711 TI - Preparation and some properties of yeast mitochondria. PMID- 4287713 TI - [On the clinical aspects and diagnosis of neuromyopathies]. PMID- 4287712 TI - Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. 3. An associated potassium-activated neutral phosphatase. PMID- 4287714 TI - The effect of age and neurological disease on the ankle jerk. PMID- 4287715 TI - Spheromembranous degeneration of muscle induced by vincristine. PMID- 4287716 TI - Infectious bovine rhinotracheitis--clinical, pathological, and virological aspects. PMID- 4287717 TI - [Aldosteronism]. PMID- 4287718 TI - [Adrenogenital syndrome]. PMID- 4287719 TI - The effect of central nervous system stimulation on erythropoiesis in rats with chronically implanted electrodes. PMID- 4287720 TI - [Case of simultaneous double primary tumor: malignant cystosarcoma phyllodes on one breast and ductal carcinoma on the other]. PMID- 4287721 TI - [Studies on the production of interferon in tissue culture infected by vaccinia virus]. PMID- 4287722 TI - [Research on the survival of Clostridium perfringens in sausage]. PMID- 4287724 TI - [Contribution to the study and treatment of amyotonia congenita]. PMID- 4287723 TI - [Renal phlebography by means of selective angiography with an iodinated emulsion. (Experimental study. 1st results)]. PMID- 4287725 TI - [Poliomyelitis]. PMID- 4287726 TI - Peripheral neuropathy in rats produced by acrylamide. PMID- 4287727 TI - Hydrolase cytochemistry of retrograde neuronal degeneration in feline lateral geniculate body. With observations on the identification of multiple forms of neural hydrolases having overlapping substrate affinities. PMID- 4287728 TI - Antigenic structure of chemically-induced hepatomas. PMID- 4287729 TI - Pathogenicity and oncogenicity of Rous sarcoma virus for mammals. PMID- 4287730 TI - [Cytochrome oxidase and peroxidase activities in the livers of rats in experimental carbon monoxide poisoning]. PMID- 4287731 TI - [On the suitability of various fixations and perchloric acid containing solutions for autoradiographic investigations of the RNA, DNA and protein metabolism]. PMID- 4287732 TI - Oxidative enzymes responsible for the conversion of 3,4-dihydroxyphenylalanine to melanin in the small intestine of rodents. PMID- 4287733 TI - Cytochemistry of cytoplasmic and intranuclear inclusions induced by bovine parainfluenza 3 virus (SF-4) in human cell cultures. PMID- 4287735 TI - Pseudomucinous cystadenocarcinoma of the ovary associated with pregnancy. Case report. PMID- 4287734 TI - Variation of localization of AMPase and ATPase activities at the plasma membrane of human prostatic epithelial cells: an electron microscopic study. PMID- 4287736 TI - Clinicopathologic conference. PMID- 4287737 TI - [Cathecholamines of the zona palisadica of the eminentia mediana of the hypothalamus in adrenalectomy, administration of hydrocortisone and stress]. PMID- 4287738 TI - [Studies on the mechanism of enzyme induction in rats and mice. IV. The effect of barbital on the anterior pituitary gland-adrenal cortex system]. PMID- 4287739 TI - Some observations on the influence of insulin, prednisolone and free amino acids on the glucose metabolism in cultivated liver tissue. PMID- 4287741 TI - Cytochemical and enzymatic disorders of lymphatic nodes in reticulosarcomatosis and malignant lymphogranulomatosis. PMID- 4287740 TI - Cytochemistry of foetal chicken liver cultivated. In vitro. PMID- 4287742 TI - Electron histochemical investigations of the effect of thioacetamide on the regenerating rat liver cell. PMID- 4287743 TI - Cytochemical studies on the relation between the Golgi structures and elaioplasts in Malva neglecta L. PMID- 4287744 TI - Prelimnary report on the therapeutic use of a synthetic corticotrophin. PMID- 4287745 TI - [On the remote results of the operation of peripheral nerve injuries treated in our clinic]. PMID- 4287746 TI - [Clinical aspects of hepatoma in children, with special reference to its specific features]. PMID- 4287747 TI - Effect of phosphates upon experimental skin calcinosis. PMID- 4287748 TI - Substrate and product inhibition of rabbit muscle lactic dehydrogenase heart (H4) and muscle (M4) isozymes. PMID- 4287749 TI - Properties of dipeptidyl arylamidase I of the pituitary. Chloride and sulfhydryl activation of seryltyrosyl-beta-naphthylamide hydrolysis. PMID- 4287751 TI - Further evidence for the accumulation of a hydroxyproline-deficient, collagenase degradable protein during collagen biosynthesis in vitro. PMID- 4287750 TI - Localization and partial characterization of an aldehydic component in tropocollagen. PMID- 4287752 TI - Action of the murine toxin of Pasteurella pestis on enzyme complexes of the electron transport system. PMID- 4287753 TI - Cofactors and erythrocyte glycolytic capacity. PMID- 4287754 TI - D-fructose 1-phosphate kinase, a new enzyme instrumental in the metabolism of D fructose. PMID- 4287755 TI - Studies on the electron transfer system. LXVI. Effect of diphosphopyridine nucleotide deficiency on respiration, respiratory control, and phosphorylation in mitochondria. PMID- 4287756 TI - Constitutive inorganic pyrophosphatase of Escherichia coli. II. Nature and binding of active substrate and the role of magnesium. PMID- 4287758 TI - The enzymatic reduction of nicotinamide N-oxide. PMID- 4287757 TI - Electron spin resonance studies of the denaturation of oxy- and methemoglobin. Spectra and solvent interactions. PMID- 4287759 TI - Studies of carcinogenesis by avian sarcoma viruses. II. Virus-induced increase in hyaluronic acid synthetase in chicken fibroblasts. PMID- 4287760 TI - Influence of glucosylation of deoxyribonucleic acid on hydrolysis by deoxyribonucleases of Escherichia coli. PMID- 4287761 TI - Glycopeptides from bovine aorta glycoprotein. PMID- 4287762 TI - The chondroitin 4-sulfate-protein linkage. PMID- 4287763 TI - [A patient with the Morgagni-Stewart-Morel syndrome and Tecomatosis of the ovaries]. PMID- 4287765 TI - Multiple primary mixed tumors of the salivary gland. A case report. PMID- 4287764 TI - [Studies on passive immunity to respiratory viruses under experimental conditions]. PMID- 4287766 TI - [Ectopic uncontrolled hormonal activity]. PMID- 4287767 TI - [Contribution to the problems of bronchial adenomas]. PMID- 4287768 TI - Decarboxylation of 2-keto fatty acids by brain. AB - An enzyme system consisting of washed acetone powder of pig brain, adenosine triphosphate, nicotinamide adenine dinucleotide, magnesium, fumaric acid, and ascorbic acid was found to catalyze the oxidative decarboxylation of 2 ketostearic acid. The products were carbon dioxide and heptadecanoic acid. Washing the enzyme powder with ethylene-diaminetetraacetate and other chelating agents destroyed the activity. Further properties of the enzyme system are described. It is believed that this enzyme system accounts in part for the 1 carbon degradation route for brain fatty acids. PMID- 4287769 TI - Synthesis and characterization of 1- and 2-monoglycerides of anteiso fatty acids. AB - The branched-chain fatty acids D-(+)-12-methyltetradecanoic acid (C(15) anteiso) and D-(+)-14-methylhexadecanoic acid (C(17) anteiso) were isolated from the lipids of Listeria monocytogenes and their 1- and 2-monoglycerides were prepared. Reaction intermediates and products were purified without isomerization by column chromatography. Thin-layer chromatography on Florisil impregnated with boric acid and nuclear magnetic resonance were used in characterizing the 1- and 2 monoglycerides. The value of the latter method for analyzing glyceride structure is discussed. PMID- 4287770 TI - Electron microscopy of the lemmocyte in peripheral nerve tumors (neurolemmomas). PMID- 4287771 TI - Pancreatoduodenectomy for islet-cell tumor of the pancreas in infancy and childhood. Case report with five-year survival. PMID- 4287772 TI - [On poisoning manifestations due to hydrocyanic acid and control of the course of poisoning in experimental animals]. PMID- 4287773 TI - Composition and properties of a cell-membrane fraction from the polymorphonuclear leucocyte. AB - 1. The composition of a vesicular cell-membrane fraction from leucocytes has been studied. The bulk of the mass is accounted for as protein and lipid. A small amount of carbohydrate, including some N-acetylneuraminic acid, is present. The phospholipid/cholesterol molar ratio is 1.4 and differs from that for the whole cell. 2. Labile phosphorus groups are present in the membrane but the analysis is complicated by the presence of phosphorus occluded in the membrane vesicles. 3. Leucocidin does not change the gross composition of the membranes or alter the amount or reactivity of the phosphorus compounds. 4. The cell-membrane fraction has considerable avidity for an impurity present in commercial [(32)P]orthophosphate. When this is removed [(32)P]orthophosphate or [(32)P]ATP does not label the membrane. 5. The presence of an NADH(2)-cytochrome c oxidoreductase and an alkaline phosphatase is described. The adenosine triphosphatase activity of the membrane has not been found to depend on the presence of Na(+) or K(+). PMID- 4287774 TI - [Watery diarrhea and hypokalemia associated with a non-insulin-secreting islet cell tumor. Apropos of a case with immediate and definitive cure of the diarrhea by tumoral excision. Nosologic discussion of this syndrome and Zollinger-Ellison syndrome]. PMID- 4287775 TI - Adenovirus infections in servicemen in Finland. PMID- 4287776 TI - [The hormonal regulation of alkaline and acid phenylphosphatases, of acid proteinase and of alanyl-glycine dipeptidase of the oviduct of Rana esculenta. I. Action of 17-beta-estradiol]. PMID- 4287777 TI - Role of thyroid hormones in lipolysis. PMID- 4287778 TI - Adrenal-dependent circulatory responses to angiotensin in the cat. PMID- 4287779 TI - Effects of angiotensin, epinephrine, norepinephrine, and vasopressin on venous return. PMID- 4287780 TI - Fluorescence-inducing corticosteroids in peripheral blood of newborn infants: response to ACTH and operation. PMID- 4287781 TI - Surgical applications of ethiodol with chlorophyll in lymphangiography: histopathologic, radiographic and clinical disadvantages in 36 cases. PMID- 4287782 TI - Adenocarcinomas of the anal canal and peri-anal tissues. PMID- 4287783 TI - Mesenchymal hamartoma of the liver. Case report and literature review. PMID- 4287784 TI - Sebaceous lesions of the parotid. Report of two cases. PMID- 4287785 TI - p-Hydroxypropiophenone vs CCL4-induced injury. PMID- 4287786 TI - Biosynthesis of NAD and nicotinic acid by Clostridium butylicum. PMID- 4287788 TI - Immunologic responsiveness and the induction of experimental neoplasms. PMID- 4287787 TI - Stable phosphorylating submitochondrial particles from baker's yeast. PMID- 4287789 TI - [Simultaneous administration of ACTH and dexamethasone]. PMID- 4287790 TI - [The effect of gonadotropins on corticosteroids and some histochemical reactions in the brown fat tissue of white rats]. PMID- 4287791 TI - [Hormonal regulation of sodium balance. A review]. PMID- 4287792 TI - The separation of some pairs of allylic-propenylic isomers by TLC on silica impregnated with silver nitrate. PMID- 4287793 TI - [On a few metabolic diseases of bred cattle with special attention to their drug therapy]. PMID- 4287794 TI - [Effect of promazine on the activity of some liver and blood enzymes in carbon tetrachloride poisoning]. PMID- 4287795 TI - [On the problem of the route of infection in cytomegalia (generalized cytomegalia in twins)]. PMID- 4287796 TI - Some observations on the diagnosis of rectal gonorrhoea in both sexes using a selective culture medium. PMID- 4287797 TI - [Phosphatase activities in the squamous epithelium of the uterine cervix in normal, abnormal and carcinomatous states]. PMID- 4287798 TI - [Studies on the effects of ionizing radiation on NADH2-oxidation in preparations of the mitochondria]. PMID- 4287799 TI - [Epidemic of acute respiratory disease due to adenovirus type 14]. PMID- 4287800 TI - [Pharmacodynamic research on beta-aspartyl-valyl-angiotensin II]. PMID- 4287801 TI - [The proportion method of determination of the resistance of tubercle bacilli to ethionamide, cycloserine and viomycin]. PMID- 4287802 TI - [The effect of intravenous use of premarin for hemostasis in the operations in the field of otolaryngology]. PMID- 4287803 TI - [Liver diagnosis with radioactive substances]. PMID- 4287804 TI - [Salicylic acid in the blood following the use of Salimar baths]. PMID- 4287805 TI - [Studies on the fine structure of the myeloblast in the human acute leukemias]. PMID- 4287806 TI - [Influence of experimental pyrexia on fibrinolysis]. PMID- 4287807 TI - Temperature dependence of the electrophoretic mobility of cells and quartz particles. PMID- 4287808 TI - Agar derivatives for gel electrophoresis requiring reduced endosmotic liquid flow. PMID- 4287809 TI - Adrenocortical and pituitary function following long-term prednisolone treatment. PMID- 4287811 TI - Effect of adrenal demedullation on vascular responses after immunological sympathectomy. PMID- 4287810 TI - Carotid vascular receptors and control of adrenal corticosteroid secretion. PMID- 4287812 TI - Tissue concentrations of manganese and adrenal function. PMID- 4287813 TI - Effects of sinoaortic denervation on renal and adrenal hypertension. PMID- 4287814 TI - [Action of various vasoactive amines on the normal and pathological cardiac function, mainly cardiogenic shock]. PMID- 4287815 TI - [Isolation of varicella virus on chick embryo chorioalantoic membrane]. PMID- 4287816 TI - Studies of the DPNH-cytochrome b segment of the respiratory chain of baker's yeast. PMID- 4287817 TI - Syntheses of peptides related to N-terminal structure of corticotropin. VI. The synthesis of ser 1- and gly 1-decapeptides corresponding to the first ten-amino acid sequence of corticotropin. PMID- 4287818 TI - [2 Normal pregnancies after hypophysectomy for eosinophilic adenoma of the hypophysis]. PMID- 4287819 TI - [Primary hypophyseal cancer in 13-year-old girl]. PMID- 4287820 TI - [Epidemic and sporadic keratoconjunctivitis]. PMID- 4287822 TI - [Syringocystademoma of the external auditory meatus]. PMID- 4287821 TI - [The variability of the size of plaques of the foot-and-mouth disease virus]. PMID- 4287823 TI - A physiological and simple approach to lymphography. An experimental study. PMID- 4287824 TI - Nephroblastoma (Wilms's tumor): urographic diagnosis and prognosis. PMID- 4287825 TI - Primary carcinoma of the liver. PMID- 4287826 TI - Study of the thoracico-abdominal lymphatic system. I. Lymph node perfusion technique. PMID- 4287827 TI - Study of the thoracico-abdominal lymphatic system. II. Lymph node perfusion by overfill technique. PMID- 4287828 TI - The specific cleavage of tyrosyl-peptide bonds by electrolytic oxidation. PMID- 4287829 TI - The stoichiometry and absorption spectra of components a and a-3 in cytochrome c oxidase. PMID- 4287830 TI - Effect of adenylic acid on the regulatory nicotinamide-adenine dinucleotide specific isocitrate dehydrogenase. PMID- 4287831 TI - Brain tumors of diverse germinal origin arising in juxtaposition. Report of three cases. PMID- 4287832 TI - [Effects of single injections and intravenous infusions of norepinephrine and angiotensin on electrocardiographic pattern of a dog in shock]. PMID- 4287833 TI - [Behavior of the adrenal reserve and ACTH pituitary reserve and attempted ACTH block in treated and untreated acromegalic cases]. PMID- 4287834 TI - Steroids in human skin and hairs. I. Zimmermann chromogens in the skin of normal and of hirsute women. PMID- 4287835 TI - Steroids in human skin and hairs. 3. Cholesterol in the skin and hairs of normal and hirsute women, and in the hairs of normal men. PMID- 4287836 TI - Myoepithelial cells in carcinoma of human breast. PMID- 4287837 TI - Electron microscopic evaluation of the pathogenesis of porcine polioencephalomyelitis. PMID- 4287838 TI - The cytopathology of swine pox in the skin of swine. PMID- 4287839 TI - The hydrolysis of unimolecular films of P32-labelled lecithin, phosphatidylethanolamine and phosphatidylinositol with phospholipase A (Naja naja venom). PMID- 4287840 TI - Heat-sensitive deoxyribonuclease activity in cells infected with herpes simplex virus. PMID- 4287841 TI - The effects of adenine nucleotides on carbohydrate metabolism in pigeon-liver homogenates. AB - 1. The effects of added AMP on carbohydrate metabolism were investigated in pigeon-liver homogenates, which can degrade glucose and synthesize it from lactate. Suitable experimental conditions were established for studying such effects, including the addition of P(i) (20mm) to stabilize adenine nucleotides and supplementation with NAD(+) (0.5mm). 2. Lactate increased the rate of oxygen consumption and kept the concentration of ATP high and that of AMP relatively low. 3. Added AMP (1.25-5mm) raised the net rate of carbohydrate removal and inhibited the net formation of glucose from lactate, as well as the incorporation of lactate into glucose. These effects were accompanied by a fall in the concentrations of hexose 6-phosphates and a rise in those of fructose diphosphate and triose phosphates. When the activity of glyceraldehyde 3-phosphate dehydrogenase was limited experimentally by a low concentration of NAD(+) or when it was blocked by iodoacetate, the accumulations of fructose diphosphate and triose phosphates were large and accounted for most of the carbohydrate degraded in the presence of AMP. 4. AMP also inhibited the conversion of pyruvate into phosphoenolpyruvate. Data on the concentrations of pyruvate, phosphoenolpyruvate and intermediates of the tricarboxylic acid cycle, as well as on isotope distribution, suggest that the effect was due to inhibition of phosphoenolpyruvate carboxykinase. 5. The results indicate that in the homogenates phosphofructokinase and fructose diphosphatase, controlled in their activity by adenine nucleotides and other cell constituents, are enzymes which regulate the direction of carbohydrate metabolism (degradation or synthesis) in the liver. 6. It is suggested that active transport of adenine nucleotides, citrate, Mg(2+), Ca(2+), P(i) and other cell constituents may play a role in regulating the activity of enzymes which are affected by these substances. 7. A procedure is described for generating alkali in a closed manometer vessel, by mixing mercuric oxide and a solution of sodium iodide, for use in a method for measuring the oxygen consumption at physiological bicarbonate concentrations. PMID- 4287842 TI - The route of ethanol formation in Zymomonas mobilis. AB - 1. Enzymic evidence supporting the operation of the Entner-Doudoroff pathway in the anaerobic conversion of glucose into ethanol and carbon dioxide by Zymomonas mobilis is presented. 2. Cell extracts catalysed the formation of equimolar amounts of pyruvate and glyceraldehyde 3-phosphate from 6-phosphogluconate. Evidence that 3-deoxy-2-oxo-6-phosphogluconate is an intermediate in this conversion was obtained. 3. Cell extracts of the organism contained the following enzymes: glucose 6-phosphate dehydrogenase (active with NAD and NADP), ethanol dehydrogenase (active with NAD), glyceraldehyde 3-phosphate dehydrogenase (active with NAD), hexokinase, gluconokinase, glucose dehydrogenase and pyruvate decarboxylase. Extracts also catalysed the overall conversion of glycerate 3 phosphate into pyruvate in the presence of ADP. 4. Gluconate dehydrogenase, fructose 1,6-diphosphate aldolase and NAD-NADP transhydrogenase were not detected. 5. It is suggested that NAD is the physiological electron carrier in the balanced oxidation-reduction involved in ethanol formation. PMID- 4287843 TI - Sucrose utilization by Zymomonas mobilis: formation of a levan. AB - 1. Molar growth-yield coefficients of Zymomonas mobilis for glucose, fructose, glucose plus fructose, and sucrose are reported. Yield coefficients for sucrose are appreciably lower than those for the equivalent concentrations of glucose plus fructose. 2. Only 2.6% of [U-(14)C]glucose supplied in the growth medium is incorporated into cell substance by Z. mobilis utilizing glucose as the energy source. 3. During growth on sucrose a levan is formed. It has been characterized and shown to resemble other bacterial levans. 4. Levan formation from sucrose could be demonstrated with both washed cell suspensions and cell extracts of Z. mobilis. 5. Sucrose phosphorylase could not be demonstrated in extracts of the organism. PMID- 4287844 TI - Factors controlling amino acid incorporation by ribosomes from krebs II mouse ascites-tumour cells. AB - 1. A ribosome-cell sap system capable of supporting the incorporation of (14)C labelled amino acids into protein has been prepared from Krebs II mouse ascites tumour cells. The requirements of this system for optimum activity and response to added messenger RNA have been investigated. One such system has been obtained for which amino acid incorporation is almost wholly dependent on the addition of suitable messenger RNA. 2. Ribosomes of widely different but predictable activities in the cell-free system have been prepared from Krebs cells pretreated in a variety of ways. The factors in the pretreatment of the cells responsible for these differences have been investigated. 3. The structural and functional properties of these different ribosome preparations and their response to exogenous messenger RNA have been examined and are discussed in the light of modern concepts of the control of protein synthesis. PMID- 4287846 TI - The effect of the chronic administration of barbitone sodium on pituitary adrenal function in the rat. PMID- 4287847 TI - Double infection of newborn Syrian hamsters with simian virus 40 and human adenovirus 12. PMID- 4287845 TI - Activities of some enzymes concerned with citrate and glucose metabolism in transplanted rat hepatomas. AB - 1. Certain enzymes concerned with citrate and glucose metabolism have been measured in two transplanted rat hepatomas, one induced with ethionine (minimal deviation type) and one induced with dimethylaminoazobenzene. In these hepatomas both citrate-cleavage enzyme and NADP-linked isocitrate dehydrogenase in the soluble fraction of the cell were approximately one-third of the values for normal rat liver. These changes have been discussed in relation to the increased citric acid content of tumours and depressed rate of fatty acid synthesis. 2. The glucose-ATP-phosphotransferase activity was below normal liver values in the ethionine-induced tumour but greater than normal in the dimethylaminoazobenzene induced hepatoma. The apparent K(m) values for the glucose-ATP phosphotransferases of these hepatomas were approx. 8x10(-5)m; no evidence was found for an enzyme with a high K(m) for glucose equivalent to liver glucokinase. 3. Of the enzymes of the pentose phosphate pathway, glucose 6-phosphate dehydrogenase activity was three to five times as great whereas 6 phosphogluconate-dehydrogenase activity was the same or lower than normal liver in the ethionine-and dimethylaminoazobenzene-induced tumours respectively. PMID- 4287848 TI - Metabolism of deoxyribonucleotides. II. Enzymatic phosphorylation of deoxycytidylic acid in normal rat liver and rat ascites hepatoma cells. PMID- 4287849 TI - Differences between the microsomes of normal rat liver and of N-2 fluorenylacetamide-induced rat hepatoma as determined by the paired label antibody technic. PMID- 4287850 TI - Systematic oscillations in metabolic activity in rat liver and in hepatomas. I. Morris hepatoma No. 7793. PMID- 4287851 TI - High molecular weight RNA from avian myeloblastosis virus. PMID- 4287852 TI - Biochemical studies on inositol. IX. D-Inositol 1-phosphate as intermediate in the biosynthesis of inositol from glucose 6-phosphate, and characteristics of two reactions in this biosynthesis. PMID- 4287853 TI - An electron paramagnetic resonance study of 3,4-dihydroxyphenylethylamine beta hydroxylase. PMID- 4287854 TI - Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids. PMID- 4287855 TI - On the relative efficacy of nicotinamide and nicotinic acid as precursors of nicotinamide adenine dinucleotide. PMID- 4287856 TI - Studies on the electron transfer system. LXV. Formation of membranes by purified cytochrome oxidase. PMID- 4287857 TI - Reversible inactivation of dehydrogenases. PMID- 4287858 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. XI. Stimulation of oxidative phosphorylation by coupling factors and oligomycin; inhibition by an antibody against coupling factor 1. PMID- 4287859 TI - Activation and inhibition in the phosphoglucomutase system. PMID- 4287860 TI - The fixation of hydrocyanic acid by a psychrophilic basidiomycete. PMID- 4287861 TI - An endonuclease from mitochondria of Neurospora crassa. PMID- 4287862 TI - The structure of extracellular phosphorylated galactans from Sporobolomyces yeasts. PMID- 4287863 TI - [Cytochromes]. PMID- 4287864 TI - [Characteristics of steroidogenesis and metabolism of corticosteroids in different forms of Cushing's disease]. PMID- 4287865 TI - Hypogammaglobulinemia with thymoma, hemolytic anemia, and disseminated infection with cytomegalovirus. PMID- 4287866 TI - The UCLA interdepartmental conference. Opportunistic pulmonary infections. PMID- 4287867 TI - [Virilizing adrenal tumors]. PMID- 4287868 TI - Wilm's tumour. PMID- 4287869 TI - Antiviral agents. II. Substituted morpholinium quaternary salts. PMID- 4287870 TI - Nucleosides from homoribose. PMID- 4287871 TI - Enzymic properties of subcellular phosphohydrolases in bovine brain cortex. Brain nucleotide phosphohydrolases. PMID- 4287872 TI - Induction with nitrous acid of dextran sulfate resistance in type 1 poliovirus. PMID- 4287873 TI - Characteristics of rapidly sedimenting ribonucleic acid from Harris strain Rous sarcoma virus and infected cells. PMID- 4287874 TI - Immunological evidence for a specific DNA polymerase produced after infection by herpes simplex virus. PMID- 4287875 TI - Avian myeloblastosis virus (AMV) biosynthesis in chick embryo cells: studies of the particles released by trypsin from the infected cells. PMID- 4287876 TI - Hamster tumor cells doubly transformed by SV40 and polyoma viruses. PMID- 4287877 TI - Antigenic variation among polyoma viruses from different sources demonstrated by plaque neutralization. PMID- 4287878 TI - Unstable DNA synthesized by polyoma virus-infected cells. PMID- 4287879 TI - Clinical and steroid metabolic studies in four siblings with congenital virilizing adrenal hyperplasia. PMID- 4287880 TI - Studies on the metabolism of C-21 steroids in the human foeto-placental unit. 2. Metabolism of pregnenolone sulphate by midterm placentas perfused in situ. PMID- 4287882 TI - A novel rice-egg sandwich for mass propagation of Entamoeba histolytica on agar plates. PMID- 4287881 TI - [Action of the poliomyelitis and Coxsackie viruses on the renal cells of the monkey (Macaca mulatta Shaw)]. PMID- 4287883 TI - [Comparative resistance of enteroviruses and Escherichia coli bacilli in water disinfection with gamma-irradiation]. PMID- 4287885 TI - The inhibiting effect of thymectomy on the incidence of leukemia in rats inoculated by Mazurenko virus. PMID- 4287884 TI - The recovery of a virus in experimental mouse LaH leukemia. PMID- 4287886 TI - A contribution to the study on an experimental virus leukemia of CBA mice strain by the method of fluorescent antibody detection. PMID- 4287887 TI - Chronic allergic neuropathy in the rabbit. PMID- 4287888 TI - The chemistry of flavins and flavoproteins. II. Inhibition of the photoreduction of flavin nucleotides and analogues. PMID- 4287889 TI - Charge-transfer complexes of nicotinamide-adenine dinucleotide analogues and flavin mononucleotide. PMID- 4287890 TI - One-electron-transfer reactions in biochemical systems. I. Kinetic analysis of the oxidation-reduction equilibrium between quinol-quinone and ferro ferricytochrome. PMID- 4287891 TI - Effect of electrolytes on the paramagnetic susceptibility of ferriprotoporphyrin IX in solution. PMID- 4287892 TI - [On the effect of ultrasonic waves on the structure and biological activity of antibiotics of polypeptide nature (polymyxin M)]. PMID- 4287893 TI - [Report on zoo-sanitary regulations in force on the exportation and importation of live animals and animal products in Ivory Coast]. PMID- 4287894 TI - [The sanitary situation and preventive methods applied in Ivory Coast in 1964]. PMID- 4287895 TI - Antibodies to DNA in mammals with Rous tumours. PMID- 4287896 TI - An attempt at in vitro sensitization of immunologically competent cells against tumour specific antigen. PMID- 4287897 TI - Relationship of Rous virus to guinea-pig and hamster cells in vitro. PMID- 4287898 TI - Characterization of the products formed by the RNA polymerases of cells infected with encephalomyocarditis virus. PMID- 4287899 TI - Corticotrophin-secreting carcinomas. PMID- 4287900 TI - Cushing's syndrome: adrenocortical hyperactivity secondary to neoplasms arising outside the pituitary-adrenal system. PMID- 4287901 TI - Liver response tests. VII. Coumarin metabolism in relation to the inhibition of rat-liver glucose 6-phosphatase. PMID- 4287902 TI - [The detection of complement-deviating herpetic antibodies in 302 subjects]. PMID- 4287903 TI - A case of infectious bovine rhinotracheitis. PMID- 4287904 TI - Phosphorus nuclear magnetic resonance study of phosphoproteins. I. Chemical nature of phosphorus atoms in bovine alpha-s-casein. PMID- 4287905 TI - A theoretical study of hepatic glycogen metabolism. PMID- 4287906 TI - The stereochemistry of the conversion of D and L 1,2-propanediols to propionaldehyde. PMID- 4287907 TI - The release of enzymes by osmotic shock from Escherichia coli in exponential phase. PMID- 4287908 TI - The inhibition by citrate of inorganic pyrophosphate-glucose phosphotransferase and glucose 6-phosphatase. PMID- 4287909 TI - Biosynthesis of streptomycin. 3. Origin of the carbon atoms of streptose. PMID- 4287910 TI - Reversibility of steroid delta-isomerase. 3. The soluble enzyme of Pseudomonas testosteroni. PMID- 4287912 TI - A new intermediate in the biosynthesis of squalene. PMID- 4287911 TI - The biosynthesis of cell wall lipopolysaccharide in Escherichia coli. 3. The isolation and characterization of 3-deoxyoctulosonic acid. PMID- 4287913 TI - Studies on cytochrome c peroxidase. VII. Electron paramagnetic resonance absorptions of the enzyme and complex ES in dissolved and crystalline forms. PMID- 4287914 TI - [Toxic effect of polymyxin. Experiences with clinical material on 307 patients]. PMID- 4287915 TI - [Occurrence, frequency and multiple occurrence of intestinal parasites in Ethiopia]. PMID- 4287916 TI - Measurements of the human fetal ribs. Data about the determination of the body length and age based on the measurements of the ribs. PMID- 4287917 TI - [Studies on the neurovirulence of the attenuated poliovirus type 3 (USOL-D) in monkey experiments]. PMID- 4287918 TI - Studies of myocardial oxidative enzymes during histaminic shock. PMID- 4287919 TI - [Adrenocortical hyperactivity in patients with lung cancer and surgery]. PMID- 4287920 TI - [New hydrolytic procedure applied to gel filtration of urinary conjugates of estrogens]. PMID- 4287921 TI - Physiological studies on trematodes: phosphatase systems in Gastrothylax crumenifer. PMID- 4287922 TI - Anemia in rheumatoid arthritis. PMID- 4287923 TI - [Comparative study on the ACTH-releasing activities of berberine, palmatine and tetrahydropalmatine (Corydalis B) in the rat]. PMID- 4287924 TI - [Aldosterone studies in pemphigus]. PMID- 4287926 TI - Metabolic inhibition of mammalian uridine diphosphate galactose 4-epimerase in cell cultures and in tumor cells. PMID- 4287927 TI - Further studies on the properties of liver propionyl coenzyme A holocarboxylase synthetase and the specificity of holocarboxylase formation. PMID- 4287925 TI - [On the enzyme histochemistry of basalioma]. PMID- 4287928 TI - Enzymes of nucleic acid metabolism from mung bean sprouts. I. Fractionation and concentration of phosphomonoesterase, ribonucleases M1 and M2, 3'-nucleotidase, and deoxyribonuclease. PMID- 4287929 TI - The enzymatic phosphorylation of ribonucleic acid and deoxyribonucleic acid. I. Phosphorylation at 5'-hydroxyl termini. PMID- 4287930 TI - The enzymatic phosphorylation of ribonucleic acid and deoxyribonucleic acid. II. Further properties of the 5'-hydroxyl polynucleotide kinase. PMID- 4287931 TI - Crystallization and properties of uridine diphosphate glucose pyrophosphorylase from liver. PMID- 4287932 TI - Electron spin resonance studies of native and denatured methemoglobin. pH effects. PMID- 4287933 TI - Cytochrome c peroxidase, a mitochondrial enzyme of yeast. PMID- 4287934 TI - Trophoblastic tumors as they are in Japan. 2. PMID- 4287935 TI - Studies on chemotherapy of trophoblastic tumors. PMID- 4287936 TI - Serological comparison of selected parasitic and free-living amoebae in vitro, using diffusion-precipitation and fluorescent-antibody technics. PMID- 4287937 TI - [Endocrine diseases]. PMID- 4287938 TI - Immunological tolerance of neonatally infected mice to the Moloney leukaemia virus. PMID- 4287939 TI - [Eosinopenia after the administration of ACTH in disseminated sclerosis]. PMID- 4287940 TI - [Cancerization of the skin of the breast in Paget's disease. A further interpretation of its mechanism]. PMID- 4287941 TI - [Diuretics and reactivity of aortic strips to some physiological stimuli]. PMID- 4287942 TI - The endocrinological aspects of benign intracranial hypeertension. PMID- 4287943 TI - Threshold stimulation for nerve conduction studies in man. PMID- 4287945 TI - Rous tumors in monkeys. PMID- 4287944 TI - An experimental viral pneumonia in swine. AB - Pneumonia resulted when a porcine entero-virus, ECPO-6, was inoculated intranasally into four and six week old, colostrum deprived, specific pathogen free piglets. Clinical signs consisted of mild depression, rapid breathing with rectal temperatures reaching 104-105 F five to six days after infection. Pneumonic lesions, both gross and microscopic were present 21 days post infection. Although the virus was readily isolated from the cecal contents of infected pigs three weeks after infection the virus was not recovered from infected lungs after the first 7-10 days. PMID- 4287946 TI - Decreased susceptibility to the mammary tumour agent in mice with advancing age. PMID- 4287948 TI - Interrelationships of contacting cells in the cell complexes of mouse ascites hepatoma. PMID- 4287947 TI - Influence of epithelio-mesenchymal interactions on tumor induction by polyoma virus. PMID- 4287949 TI - Demonstration of common specific antigen(s) in mouse and hamster polyoma tumors. PMID- 4287950 TI - Studies on carcinogenesis by avian sarcoma viruses. 3. The differential effect of serum and polyanions on multiplication of uninfected and converted cells. PMID- 4287951 TI - Formation of lung colonies by polyoma-transformed rat embryo cells. PMID- 4287952 TI - Study of S91 mouse melanomas by electron paramagnetic resonance spectroscopy and tissue culture. I. The effect of cysteine on blue light signals and on growth in vitro. PMID- 4287953 TI - Nonspecific life shortening in male mice exposed to the mammary tumor agent. PMID- 4287954 TI - Production and susceptibility to interferon of polyoma virus variants of high and low oncogenic properties. PMID- 4287955 TI - [Investigation of methods of extraction and purification of adrenocorticotropic hormone]. PMID- 4287956 TI - Body distribution of Lipiodol 131-J following intralymphatic radiotherapy. PMID- 4287957 TI - The pathogenesis and pathology of infection in calves with a strain of bovine adenovirus type 3. PMID- 4287958 TI - Further studies on the actions of peptides on the superior cervical ganglion and suprarenal medulla. PMID- 4287960 TI - The urinary excretion of inorganic pyrophosphate by normal subjects and patients with renal calculus. PMID- 4287959 TI - Respiratory virus antibodies in sera of persons living in isolated communities. AB - It is known that young adults living in urban areas of many different parts of the world have serum antibodies against a number of viruses commonly associated with respiratory disease. It seemed possible that people living in isolated regions of the world, having infrequent contact with others, might have fewer virus infections, and, if so, that this would be reflected in an infrequent occurrence or low level of antibodies in their sera. Therefore sera were obtained from children and adults living in remote village-type communities in the Pacific (Micronesian islanders), North America (Eskimos) and South Africa (Hottentots). Antibodies against influenza viruses A2 and B, parainfluenza virus types 1, 2 and 3, reovirus types 1, 2 and 3, and two M rhinoviruses were present usually in a high proportion of sera in the three population groups; the results differed little from those for non-isolated communities. It seems that an extreme degree of isolation is required to reduce contact with viruses so that a population has little or no antibody. PMID- 4287961 TI - [Influence of thermal denaturation on the radiolytic yield of desoxyribonucleic acid in solid phase]. PMID- 4287962 TI - [Research on energy metabolism in mouse liver tissue after total-body irradiation]. PMID- 4287963 TI - Factors affecting the reversible dissociation of dehydrogenases. PMID- 4287964 TI - The twisted circular form of polyoma viral DNA. PMID- 4287965 TI - The UV-induced triplet state in DNA. PMID- 4287966 TI - Electron spin resonance of an irradiated single crystal of thymidine. PMID- 4287967 TI - Complement fixation and tissue culture assays for mouse leukemia viruses. PMID- 4287968 TI - [On cerebrosidase of the glial tissue of brain tumors]. PMID- 4287969 TI - [Effect of experimental training on induced synthesis of NAD in the organism]. PMID- 4287970 TI - [Alteration of ACTH metabolism in children resulting from treatment with a chemical inhibitor 11-beta-hydroxylase. I. Urinary secretion of 17 hydroxycorticosteroids resulting from treatment with a chemical inhibitor of 11 beta-hydroxylase in normal children]. PMID- 4287971 TI - [On changes in the activity of lactate dehydrogenase and its isoenzymes in the adrenal glands under the effect of adrenocorticotropic hormones]. PMID- 4287972 TI - Studies on lipoamide dehydrogenase of bakers' yeast. V. The effects of metal ions and sulfhydryl reagents on the absorption spectrum of the enzyme. PMID- 4287973 TI - Studies on brain phospholipids. IV. Post-mortem breakdown of phosphoinositides and phosphatidic acid, and P32-incorporation into phospholipids in various states of the tissue. PMID- 4287974 TI - Kinetic studies on the oxidation and reduction of the protoheme moiety of yeast L(+)-lactate dehydrogenases. PMID- 4287975 TI - Effects of digitonin and tocopherol on bovine heart muscle reduced diphosphopyridine nucleotide- and succinate-cytochrome c reductase and cytochrome c oxidase. PMID- 4287976 TI - The angiotensin infusion test. PMID- 4287977 TI - [Tumor of pubic region (clear cell myoepithelioma)]. PMID- 4287978 TI - [Chemotherapy of trophoblastic tumors]. PMID- 4287979 TI - [Case of ciliated epithelioma of the cervix uteri]. PMID- 4287980 TI - Mixed infections or contaminations of bovine viral diarrhea virus with infectious bovine rhinotracheitis virus. PMID- 4287981 TI - Infectivity of three porcine polioencephalomyelitis viruses for germfree and pathogen-free pigs. PMID- 4287982 TI - The effect of ultrasound on the gastric mucosa and its secretion of acid. PMID- 4287983 TI - [Evaluation of the adrenal cortex function during glucocorticoid treatment with the aid of the synacthen brief test]. PMID- 4287984 TI - Coexisting bronchogenic carcinoma and tuberculosis. PMID- 4287985 TI - Kinetic studies of adenine phosphoribosyltransferase. PMID- 4287986 TI - Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. IV. Saccharopine dehydrogenase. PMID- 4287987 TI - A superhyperfine interaction involving 33-S in the iron-containing proteins of Azotobacter vinelandii. PMID- 4287988 TI - Individual 17-ketosteroid excretion in a case of arrhenoblastoma and its response to corticotrophin and human chorionic gonadotrophin stimulation and to dexamethasone inhibition. PMID- 4287989 TI - Variations of urinary antigens in trophoblastic proliferative disorders. PMID- 4287990 TI - Report of a new long-acting (Zn) synthetic ACTH (CIBA 36716 Ba-24 corticotrophin) on adrenal secretion in human subjects. PMID- 4287991 TI - Delayed hypersensitivity to herpes simplex virus in the guinea pig. PMID- 4287992 TI - Distribution of the intestinal factor of normal mice which inactivates murine virus hepatitis. PMID- 4287993 TI - Inhibition of transplantable and spontaneous murine tumours by the M-P virus. PMID- 4287994 TI - Hyperlipaemia following viral infection in the chicken embryo: a new syndrome. PMID- 4287995 TI - Recurrent pancreatic adenomas. PMID- 4287996 TI - [On the mechanism of action of tetracycline antibiotics. 6. Phosphatase activity of sensitive and polyresistant staphylococci and their inhibition by oxytetracycline]. PMID- 4287997 TI - [Syringadenoma papilliferum]. PMID- 4287998 TI - [ACTH reserve tests in obesity in childhood using the metopirone test]. PMID- 4287999 TI - [Prognosis and x-ray therapy of cerebral tumors]. PMID- 4288000 TI - [Use of broncho-abrodil in hysterosalpingography]. PMID- 4288001 TI - The results of hepatic lobectomy for primary carcinoma of the liver. PMID- 4288002 TI - Survival of dogs treated with hyperbaric oxygen following hepatic artery ligation. PMID- 4288003 TI - HPO in clostridial toxicity and strangulation obstruction. PMID- 4288004 TI - Primary cancer of the liver in childhood. PMID- 4288005 TI - Studies on the mechanism of action of colistin. IV. Activation of "latent" ribonuclease in Escherichia coli by colistin. PMID- 4288006 TI - Transformation of duck embryo cells in vitro by avian tumour virus B77. PMID- 4288007 TI - Further studies on the immunobiology of tumour RVA2 induced by RSV in C57BL strain mice. PMID- 4288008 TI - Activation of deoxycytidylate deaminase from certain embryonal and tumour tissues by 6-aza-2'-deoxycytidine-5'-monophosphate and 2'-deoxycytidine-5'-triphosphate. PMID- 4288009 TI - [On the detection of antibodies neutralizing herpesvirus hominis in 261 subjects]. PMID- 4288010 TI - [On 3 cases of primary glioma of the optic nerve]. PMID- 4288011 TI - Denaturation of lactic dehydrogenase isozymes and its clinical application. PMID- 4288012 TI - Isoprecipitin in the sera of rats resistant to tumour transplantation. PMID- 4288013 TI - Stimulation of Sendai virus multiplication by puromycin and actinomycin D. PMID- 4288014 TI - Hypothalamic regulation of ACTH secretion. PMID- 4288015 TI - Protective performance of stannous fluoride--zirconium silicate prophylaxis pastes. SAM-TR-66-7. PMID- 4288016 TI - Peristaltic reflex and hypotensive drugs. PMID- 4288017 TI - Susceptibility of the steppe-lemming to the oncogenic action of Rous sarcoma virus. PMID- 4288018 TI - Line of hamster cells transformed by the Schmidt-Ruppin strain of Rous virus in vitro. PMID- 4288019 TI - Immunologically stimulated human peripheral blood lymphocytes in vitro. I. Morphological changes. PMID- 4288020 TI - Determination of the 11-beta-hydroxylase activity in microgram samples of tissue; its quantitative histological distribution in the rat adrenal, and the influence of corticotrophin. PMID- 4288021 TI - Hydroxylamine as an inactivating agent for foot-and-mouth disease virus. PMID- 4288022 TI - Studies on Japanese B encephalitis virus vaccines from tissue culture. VI. Development of a hamster kidney tissue culture inactivated vaccine for man. 2. The characteristics of inactivation of an attenuated strain of OCT-541. PMID- 4288023 TI - Studies on Japanese B encephalitis virus vaccines from tissue culture. VI. Development of a hamster kidney tissue culture inactivated vaccine for man. 3. Potency testing of an attenuated strain of OCT-541. PMID- 4288024 TI - [Effect of cobalt on the inhibition of the cytochrome oxidase activity by potassium cynide]. PMID- 4288025 TI - Range of heat resistance of Clostridium welchii associated with suspected food poisoning. PMID- 4288026 TI - Enzymic activities in Calvatia cyathiformis during and after meiosis. PMID- 4288027 TI - Interpretation of structural detail in viruses of the polyoma group. PMID- 4288028 TI - Quantitative estimation of nuclear buds and micronuclei in bovine cells transformed by Rous sarcoma and SV 40 viruses. PMID- 4288029 TI - Body organ thermogenesis of the rat during exposure to cold and at maximal metabolic rate. PMID- 4288030 TI - Metabolic and physiological aspects of exercise at high altitude. II. Response of natives to different levels of workload breathing air and various oxygen mixtures. PMID- 4288031 TI - Comparative absorption of calcium from calcium gluconate and calcium lactate in man. PMID- 4288032 TI - [Interference of attenuated NDV and poliomyelitis virus in monolayer HeLa cell cultures]. PMID- 4288033 TI - [Studies on the function of the adrenal cortex in patients with ulcer]. PMID- 4288034 TI - Eosinophilic adenoma of the pituitary. PMID- 4288035 TI - Glucose-6-phosphatase-like activity in the human placenta, fetal liver, and decidual tissue. PMID- 4288036 TI - Incidental finding of cytomegalovirus inclusions in cervical glands. A case report. PMID- 4288037 TI - Pituitary enzymes. V. Proteolytic degradation of phosphohydrolase of 5' mononucleotides from bovine pituitary gland (EC 3.1.3.5). PMID- 4288039 TI - [Activity of alpha-amylase and glucose-6-phosphatase in the liver and blood sugar level in animals infected with plague]. PMID- 4288038 TI - [Action of RNA of the liver on tumor growth in experimental animals]. PMID- 4288040 TI - [Paget's disease of the scrotum]. PMID- 4288041 TI - The response of colostrum-deprived, specific pathogen-free pigs to experimental infection with Teschen disease virus. AB - The clinical response to Teschen disease and the excretion and rate of virus distribution in tissues of colostrum-deprived, specific pathogenfree pigs was determined. Severe, mild, and clinically inapparent responses to the disease were noticed following simultaneous intracranial and intranasal infections. Fourteen day-old pigs reacted more severely to infection than 21-day-old pigs. The virus was detected in feces 2-3 days following infection but not in stools of surviving pigs 30 days after infection. The highest concentration of virus occurred during the incubation period and before onset of paralysis; the lowest concentrations were found during terminal disease stages. In tissues collected before or immediately after death of pigs, Teschen disease virus was found in several visceral organs but not in blood, urine or urinary bladder tissue. Virus yield was highest in brain and spinal cord tissues. Highest virus concentration was found in the cervical thoracic portions of the spinal cord, thalamus and cerebellum. Other aspects of the clinical disease are discussed. PMID- 4288042 TI - Studies on the acetylcholine-stimulated incorporation of radioactive inorganic orthophosphate into the phospholipid of brain particulate preparations. II. Subcellular distribution of enzymic activity. PMID- 4288043 TI - Adenoid cystic carcinoma (cylindroma) of the palate. Report of three cases. PMID- 4288045 TI - [Attenuation of virulent fowl pox virus in tissue culture and characteristics of the attenuated virus]. PMID- 4288044 TI - [Research on interferon in childhood viral hepatitis]. PMID- 4288046 TI - [Reaction of plaque-purified and non-purified foot-and-mouth disease virus strains of the subtypes O-1, O-2, and O-3 and of the corresponding immune sera in cross-neutralization tests]. PMID- 4288047 TI - Serological classification of swine enteroviruses. PMID- 4288048 TI - [Feminizing adrenocortical tumor. A case report and studies on hormonal responsiveness of the tumor]. PMID- 4288049 TI - Respiratory infections in children at a nursery in Finland. Virologic and epidemiologic studies over a 21-month period. PMID- 4288050 TI - The appearance pattern of skeletal epiphyses among normal Finnish children during the first five years of life. PMID- 4288051 TI - Synthesis of dinucleotide anhydrides and ribonucleoside 3'-phosphate 5' pyrophosphates. PMID- 4288052 TI - Actinomycin D inhibition of avian myeloblastosis virus production by chick-embryo fibroblasts. PMID- 4288053 TI - Nicotinamide adenine dinucleotidase activity in experimental tuberculosis. PMID- 4288055 TI - Blepharoplasty following tumor surgery. PMID- 4288054 TI - Potassium-ion stimulated p-nitrophenylphosphatase activity occurring in a highly specific adenosine triphosphatase preparation from rabbit brain. PMID- 4288056 TI - Pyrophosphate and the mineralizing potential of urine. PMID- 4288057 TI - Pressor effects of angiotensin infusions into different vascular beds in the rabbit. PMID- 4288058 TI - Angiotensin blood levels in hypertensive and non-hypertensive diseases. PMID- 4288059 TI - The effect of angiotensin on renal sodium excretion: studies in normal dogs and in dogs with experimental renal artery stenosis. PMID- 4288060 TI - Adrenocorticotropins. XXXVI. Synthesis of a biologically active prolinol analog of the nonadecapeptide corresponding to the amino-terminal portion of the ACTH molecule. PMID- 4288061 TI - [A study of the effect of Flagyl on Entamoeba histolytica in culture]. PMID- 4288062 TI - [On the conservative treatment of female sterility]. PMID- 4288063 TI - Inactivation of foot-and-mouth disease virus by interaction of dye and visible light. AB - The inactivation of foot-and-mouth disease virus was studied by means of the interaction of neutral red, Toluidine Blue, and methylene blue with visible light. The virus, Type A, strain 1, CANEFA of Argentine origin, was grown in tissue culture and tested in the crude and clarified state. Virus and dye were mixed and incubated together at 4 C for 45 min in the dark, or were mixed and immediately exposed to the visible light source without prior incubation together. Mixtures of crude virus and dye, under any of the experimental conditions used, did not inactivate more than 1 to 2 logs of viral infectivity when held in the dark or when exposed to light during a period of 45 min. Complete inactivation of virus was achieved when clarified virus and dye were mixed and immediately exposed to the visible light source for 15 min. Prior incubation of clarified virus and dye permitted inactivation by methylene blue only, whereas no incubation prior to exposure resulted in three of the dyes contributing to inactivation. A concentration of 6 mug of neutral red, Toluidine Blue, methylene blue, and crystal violet was used per milliliter of virus suspension. Crystal violet was not a good viral inactivator under the conditions of the experimentation. Inactive virus induced the formation of neutralizing antibodies in adult chickens and mice. The antibody titer stimulated by the antigen treated with methylene blue and visible light was probably significant. PMID- 4288064 TI - [The role of Eimeria tenella and Eimeria necatrix in the epizootiology of enteritis in chicks induced by Welchia agni var. paludis C]. PMID- 4288065 TI - Biochemical, histochemical and ultrastructural changes in the mouse seminal vesicle after castration. PMID- 4288066 TI - Renin-angiotensin system in normal and toxemic pregnancies. I. Angiotensin infusion test. PMID- 4288067 TI - Effect of several analogs of idoxuridine on the uptake of tritium-labeled thymidine in the rabbit cornea infected with herpes simplex. PMID- 4288068 TI - The influence of p-fluoro-phenylalanine, puromycin, and actinomycin on the development of simian papovavirus (SV40). PMID- 4288069 TI - The significance of roentgenological findings in the evaluation of maturity of the newborn. A clinico-radiological study of 486 newborns. PMID- 4288070 TI - Radiation protection by sulphur in cyclohexane. PMID- 4288072 TI - Surgical prosthesis for reconstructive mandibular surgery. PMID- 4288071 TI - Evaluation of steroid therapy for active carditis. Follow-up of 1 to 14 years. PMID- 4288073 TI - [Effect of some industrial dusts on the capacity of oxygen consumption by the pulmonary tissue of albino mice]. PMID- 4288074 TI - [Review of corticotropin metabolism]. PMID- 4288075 TI - [Methods of study of adrenal cortex function]. PMID- 4288076 TI - [Influence of hydrocortisone and ACTH on the serum level and urinary excretion of hexosamines and acid mucopolysaccharides. I. Behavior of the nyctohemeral rhythm of neutral and acid glycoproteins in the serum and urine before and after intravenous administration of a single dose of hydrocortisone and ACTH]. PMID- 4288078 TI - Heterogeneity of templae RNA in adrenal glands. AB - Template RNA in adrenal glands appears to be heterogeneous in stability. The RNA that regulates synthesis of a large fraction of adrenal protein has a turnover time of 4 hours or less. The remainder of adrenal-protein synthesis, including synthesis of protein that mediates the rapid steroidogenic response to ACTH, depends on RNA with considerably greater stability. PMID- 4288077 TI - [Influence of hydrocortisone and ACTH on the serum level and urinary excretion of hexosamines and acid mucopolysaccharides. II. Behavior of the serum and urinary glycoproteins in the 10 days following the intravenous administration of a single dose of hydrocortisone and ACTH and the correlation with the endogenous adrenal rhythm]. PMID- 4288079 TI - Norepinephrine methylation in fetal rat adrenals. AB - The activity of phenylethanolamine-N-methyl transferase, the enzyme that methylates norepinephrine to form epinephrine, increases rapidly in the fetal rat adrenal during the day preceding epinephrine accumulation. The developmental increase in enzyme activity and the accumulation of epinephrine are prevented by fetal hypophysectomy (decapitation). Administration of adrenocorticotrophic hormone or cortisol acetate largely reverses the effect of fetal decapitation. PMID- 4288080 TI - Viral neoplastic transformation of hamster pineal cells in vitro: retention of enzymatic function. AB - Cultures of hamster pineal tissue infected with certain oncogenic DNA viruses undergo neoplastic transformation and produce tumors when injected into homologous hosts. Hydroxyindole-O-methyl transferase, an enzyme found exclusively in the pineal gland, is present in low concentrations in transformed pineal cells in vitro and in larger amounts in tumors produced by the injected cells. This enzyme is not present in several nonpineal tissues similarly transformed. PMID- 4288081 TI - The effect of hypothalamic implantation of 17-beta-oestradiol and systemic administration of prolactin (LTH) on sexual behaviour in male rabbits. PMID- 4288082 TI - The laboratory diagnosis of whooping cough by fluorescent antibody and by culture methods. AB - Attempts were made to hasten the identification of Bordetella pertussis by using the fluorescent antibody (FA) technique and to improve the isolation rate by culture methods. First, a comparison was made between the number of identifications of the organism by growth on Bordet-Gengou medium containing penicillin G and by staining smears of pharyngeal exudate with FA. Of 100 specimens, 29 were positive on culture and 46 were positive by the FA method. Five of the 46 were false positives. Second, 170 specimens were inoculated in quadruplicate on Bordet-Gengou medium containing either penicillin G or methicillin, and on Lacey medium containing either penicillin G or methicillin. In order there were 39, 41, 56 and 57 isolations. The isolation of Bord. pertussis on methicillin-containing media was easier than on penicillin containing media. When culture and FA methods were compared, the most reliable was found to be the inoculation of specimens on Lacey medium. PMID- 4288083 TI - Angiotensin tachyphylaxis and its reversal. PMID- 4288085 TI - Effect of hemorrhage on arterial plasma renin activity in the rabbit. PMID- 4288084 TI - A sensitive method for assay of plasma renin activity. PMID- 4288086 TI - Clinical diagnosis of hepatoma. PMID- 4288087 TI - Growth of foot-and mouth disease virus in monolayer cultures of calf thyroid cells. PMID- 4288088 TI - Electrophoretic separation of two plaque-type variants of encephalomyocarditis virus. PMID- 4288089 TI - [10-year survival after acute leukemia]. PMID- 4288090 TI - [1st trials of treatment of cerebral vascular disorders by the Bernard Weil anti edema method]. PMID- 4288091 TI - [Observation of the adrenal function in viral hepatitis using ACTH stimulation tests]. PMID- 4288092 TI - Labelling of corticotropin with iodine-125. PMID- 4288093 TI - Photochemistry of uridylyl-(3'--5')-uridine. PMID- 4288094 TI - Radioisotopic scanning as an aid in planning radiation therapy. PMID- 4288095 TI - Infectious bovine rhinotracheitiis--sudden death in feedlot cattle. PMID- 4288096 TI - Properties of motol virus in cultivation on tissue cultures and attempt at its identification. PMID- 4288097 TI - Results of study of the antigenic properties of cell components of C1. perfringens by agar gel precipitation and immunoelectrophoresis. II. Results with the use of "monospecific" antitoxic sera. PMID- 4288098 TI - The mechanism of the action of tetracycline antibiotics. 9. Inhibition of cytochrome oxidase by oxytetracycline. PMID- 4288099 TI - Hemihepatectomy; a nursing care study. PMID- 4288100 TI - Quantitative rhinovirus shedding patterns in volunteers. PMID- 4288101 TI - Adenovirus soluble antigens for human immunization: a progress report. PMID- 4288102 TI - [Muco-epidermoid tumor of the parotid gland. (Anatomo-clinical considerations)]. PMID- 4288103 TI - [Cylindromatous epithelioma with late pulmonary metastases despite the absence of local recurrences]. PMID- 4288104 TI - The effect of steroid hormones on lysosomal activity of rat ventral prostate gland in culture. PMID- 4288105 TI - Malic dehydrogenase activity in the preimplantation mouse embryo. PMID- 4288106 TI - The production of embryous nodules in neonatal rats by the intravenous injection DNA from rat hepatoma. PMID- 4288107 TI - Viraemia in haemorrhagic and other forms of smallpox. PMID- 4288108 TI - Stevens-Johnson syndrome: nonspecific parasensitivity reaction? PMID- 4288109 TI - [The histogenesis of ovarian tumors--embryological considerations]. PMID- 4288110 TI - Effect of single intravenous injections and intravenous instillations of norepinephrine and angiotensin on electrocardiographic patterns in dogs. PMID- 4288111 TI - [Anterior pituitary insufficiency. Clinical cases]. PMID- 4288112 TI - [The effect of adrenocorticotropic hormone and high ambient temperature on the metabolism of nitrogenous compounds in young pigs. II. Amino acids in the blood serum and urine]. PMID- 4288113 TI - Ecthyma contagiosum (ORF). PMID- 4288114 TI - Endocrinopathy associated with pancreatic carcinomas. Review of host factors including hyperplasia and gonadotropic activity. PMID- 4288115 TI - Effect of angiotensin on the cardiac arrhythmias induced by g-strophanthin. PMID- 4288116 TI - [Membrane potential of liver and hepatoma cells]. PMID- 4288117 TI - Influence of thymic mass on murine viral leukaemogenesis. PMID- 4288118 TI - Isolation and identification of poliovirus from a clinical specimen. PMID- 4288119 TI - [Importance of cerebral edema in the evolution of cerebro-vascular accidents]. PMID- 4288120 TI - [Stimulation of the adrenergic system by angiotensin]. PMID- 4288121 TI - [Cytochemical studies on acid phosphatase and thiamine pyrophosphatase in mammalian liver cells]. PMID- 4288122 TI - Electron microscopy of peripheral nerve terminals and marginal melanocytes in vitiligo. PMID- 4288123 TI - Thiosemicarbazone derivatives in pox virus infections. PMID- 4288125 TI - [Bronchial adenoma of the carcinoid type with carcinoid syndrome]. PMID- 4288124 TI - Asbestos--a hazard to the community. PMID- 4288126 TI - Ubiquinone in proline oxidation. PMID- 4288127 TI - The effect of basic proteins on the oxidation of exogenous NADH2 in rat liver mitochondria. PMID- 4288128 TI - Electron transport in Azotobacter vinelandii. PMID- 4288130 TI - Nicotinamide deamidase in Ehrlich ascites tumor cells. PMID- 4288129 TI - Phosphorylation associated with nitrate and nitrite reduction in Micrococcus denitrificans and Pseudomonas denitrificans. PMID- 4288131 TI - NAD+-linked D-mannitol dehydrogenase in Acetobacter suboxydans. PMID- 4288132 TI - On the role of amino groups in the structure and function of glutamate dehydrogenase. I. Effect of acetylation on catalytic and regulatory properties. PMID- 4288133 TI - On the role of amino groups in the structure and function of glutamate dehydrogenase. II. Effect of acetylation on molecular properties. PMID- 4288134 TI - Studies on the biosynthesis of nicotinamide adenine dinucleotide. 3. Comparative in vivo studies on nicotinic acid, nicotinamide, and quinolinic acid as precursors of nicotinamide adenine dinucleotide. PMID- 4288135 TI - Enzymatic phosphorylation of fish phosvitin. PMID- 4288136 TI - [Disseminated cylindroma associating a turban tumor with other localizations]. PMID- 4288138 TI - [On a case of multiple granulocellular myoblastomyoma of the tongue]. PMID- 4288137 TI - [Electron microscope study of the Graffi virus in the bone marrow of leukemic mice]. PMID- 4288139 TI - [Experimental studies on hepatitis epidemica. 3. Morphologic lesions in the spleens and lymph nodes of mice infected with the motol virus]. PMID- 4288140 TI - [Progress of the method of assessing skeletal maturity. A method of assessing skeletal age by the pelvic roentgenograms]. PMID- 4288141 TI - [Application of electromyography in detecting subclinical or atypical lesions of the facial nerve]. PMID- 4288142 TI - Transformation in vitro of mammalian cells by polyoma and Simian 40 viruses. PMID- 4288143 TI - [A case of insuloma of the pancreas]. PMID- 4288144 TI - [Synchronous pulmonary neoplasms]. PMID- 4288145 TI - [Dynamics of elimination of 5-oxy-indoleacetic acid from urine in patients with myasthenia]. PMID- 4288146 TI - [Histochemical study of thrombangitis obliterans]. PMID- 4288147 TI - [The effect of adrenocorticotropic hormone and high ambient temperature on the metabolism of nitrogenous compounds in young pigs. I. General nitrogen metabolism]. PMID- 4288148 TI - Histochemical and electron microscopic studies on the cells of the rat adrenal cortex in tissue culture. PMID- 4288149 TI - [Studies on the splitting of corticotropin in serum]. PMID- 4288151 TI - [The effect of passive immunization on the sensitizing action of pertussis bacteria. II. The formation of increased sensitivity to heterologic antigens]. PMID- 4288152 TI - [Species specific antisera for representatives of the Bordetella genus]. PMID- 4288150 TI - Studies on the action of some enzymes on the cyst wall of isolated metacerkariae from the liver fluke, Fasciola hepatica L. PMID- 4288154 TI - ACTH and adrenal hormones and catecholamine content of adrenal medulla, heart and brain. PMID- 4288153 TI - [Acute ethanol intoxication and liver metabolism]. PMID- 4288155 TI - [Bronchial adenomas. Review of the literature and description of 2 cases with malignant course]. PMID- 4288156 TI - Hyperinsulinism and islet cell tumor of the pancreas. PMID- 4288157 TI - Mixed tumours of the parotid gland with metastases. (Case report). PMID- 4288159 TI - Plasma ACTH determinations in 58 patients before or after adrenalectomy for Cushing's syndrome. PMID- 4288158 TI - Effect of estrogen administration on extravascular cortisol. PMID- 4288161 TI - [Effect of roentgen-irradiation on the growth of smallpox vaccine virus in chick embryo]. PMID- 4288160 TI - Evaluation of testicular function by measurement of urinary excretion of testosterone. PMID- 4288162 TI - Addition radicals formed by hydroxyl radical bombardment of uracil. AB - Direct addition of O-H radicals at room temperature to the carbon No.5 of the uracil ring has been proved by measurement of the proton hyperfine structure in the electron spin resonance of the resulting uracil + O-H radicals. Upon addition of the OH, the H originally bound to carbon No. 5 shifts to No. 6, thus forming a methylene group at carbon No. 6, with the two protons having equivalent coupling of 28 gauss. The spin density on carbon No. 5 is O.64. The radicals were produced when powdered samples of uracil were subjected to a low-velocity beam of O-H radicals coming from either hydrogen peroxide or water vapor under reduced pressure and subjected to an electric discharge. PMID- 4288163 TI - Spontaneous mammary tumors: decrease of incidence in mice infected with an enzyme elevating virus. AB - Mice infected with a virus which causes increased activity of lactate dehydrogenase, and of other enzymes in blood plasma, had a significantly lower incidence of spontaneous mammary carcinoma than did controls. When the experiment was terminated at 18 months, the incidence of mammary tumors in controls was 90 percent, and in infected mice, 53 percent. PMID- 4288164 TI - Pituitary tumors in mice after prolonged feeding of synthetic progestins. AB - An enhanced development of pituitary tumors was observed in virgin female mice of the C57 Leaden strain following repeated oral administration of synthetic progestins. This finding appears to parallel the co-carcinogenic enhancement of mammary tumor development elicited in C3H mice treated repeatedly with progesterone. PMID- 4288165 TI - [Some data on adenoviruses in chronic tonsillitis]. PMID- 4288167 TI - Necrotizing enterocolitis: a report of six cases. PMID- 4288166 TI - Thyroid mitochondrial respiration. PMID- 4288168 TI - Bilateral carpal and tarsal tunnel syndrome. PMID- 4288169 TI - Effects of cyclic adenosine monophosphate and melanocyte-stimulating hormone on frog skin in vitro. PMID- 4288170 TI - Distribution of collagenase in rat tissues. PMID- 4288171 TI - Mixed infection of African green monkey kidney cells by adenovirus 7 and SV 40. PMID- 4288172 TI - Isolation of macronuclei from the ciliate Tetrahymena pyriformis GL. PMID- 4288173 TI - Effect of corticosteroid hormones on rat-brain mitochondrial NADH-oxidase. PMID- 4288174 TI - Differentiation of adrenal cortex-like tissue at the hilum of the gonads in response to adrenalectomy. PMID- 4288175 TI - [Glucose-6-phosphatase and glucose-6-phosphate dehydrogenase activity of the retina and the humors in cattle]. PMID- 4288176 TI - [Clinical findings in patients, infected with adenoviruses]. PMID- 4288177 TI - Reticuloendothelial activity and local particle disposal. A comparison of the influence of modifying agents. PMID- 4288178 TI - [Distribution of Cl. perfringens in the environment]. PMID- 4288179 TI - [Determination of free silicon dioxide in dust and rocks by weight and colorimetric methods]. PMID- 4288180 TI - [On methods of isolating enteroviruses from the water of reservoirs and from sewage]. PMID- 4288181 TI - Mucinous adenocarcinoma of the urachus. PMID- 4288182 TI - Liver disease in the territory of Papua-New Guinea: a necropsy study. PMID- 4288183 TI - On the mechanism of the potentiating of the angiotensin pressor effect by guanethidine and desmethylimipramine. PMID- 4288184 TI - [Influence of chronic pretreatment with alpha-methyldopa and reserpine upon the sensitivity of the vascular system to noradrenaline and hypertensin]. PMID- 4288185 TI - The effects of norepinephrine and angiotensine on the lymphatic system. PMID- 4288186 TI - Increased cardiovascular reactivity to agiotensin caused by renin. AB - After a short period of tachyphylaxis, there is a marked and sustained enhancement of pressor re sponses to renin and angiotensin during chronic administration of renin. PMID- 4288187 TI - Effect of thymectomy on tumour production by polyoma virus in rabbits. PMID- 4288188 TI - Hydrolysis of condensed phosphates in natural waters. PMID- 4288190 TI - The use of an aqueous polymer phase system for enterovirus isolations from sewage. PMID- 4288189 TI - A comparison between virus isolations from sewage and from fecal specimens from patients. PMID- 4288191 TI - The role of nasal secretion and serum antibody in the rhinovirus common cold. PMID- 4288192 TI - Complement fixation with tissue constituents in adenovirus pneumonia. PMID- 4288193 TI - Studies on Japanese B encephalitis virus vaccine from tissue culture. VI. Development of a hamster kidney tissue culture inactivated vaccine for man. 4. Preparation and characterization of vaccine lot for human trial. PMID- 4288194 TI - Bat salivary gland virus carrier state in a naturally infected Mexican freetail bat. PMID- 4288195 TI - Angiotensinase in red cells. PMID- 4288196 TI - What brings on insulin sensitivity? PMID- 4288197 TI - A granular cell myoblastoma of the larynx. PMID- 4288198 TI - Effect of angiotensin on the pressor response to tyramine in normotensive subjects and hypertensive patients. PMID- 4288199 TI - Extraction, purification, and assay of human renin free of angiotensinase. PMID- 4288200 TI - [Effect of conjugated estrogens on the vaginal and uterine mucous membrane]. PMID- 4288201 TI - [Acidity and uropepsinogen under the action of adrenal steroids]. PMID- 4288203 TI - [Splenectomy, androgens and corticosteroids in the therapy of myelofibrosis. Description of 2 clinical cases]. PMID- 4288202 TI - [On the silicon dioxide content in the urine of Karaganda coal miners]. PMID- 4288204 TI - [On the problem of the differential diagnosis of hypoglycemias. Apropos of a case of pancreatic insuloma]. PMID- 4288205 TI - Cytomegalovirus complement-fixing antibody in microcephaly. PMID- 4288206 TI - The effects of alteration of blood-volume on the concentration of circulating angiotensin in anaesthetized dogs. AB - 1. The blood-bathed organ technique was used to assay the concentration of angiotensin in the blood of anaesthetized dogs.2. Alterations of blood volume caused inverse changes of angiotensin concentration owing to changes in the rate of generation of angiotensin which are probably due to changes of the rate of renin secretion.3. Haemorrhage of 14-26 ml. blood/kg caused an increase of 0.25 1.5 mug/min in the rate of generation and an increase of 0.1-0.33 ng/ml. in the blood concentration of angiotensin.4. The changes of angiotensin generation rate were not due to changes of renal arterial or venous pressure. They were abolished by blocking the renal nerves with lignocaine; they showed a consistent inverse correlation with central venous pressure but not with systemic arterial pressure.5. It is concluded that changes of blood volume bring about changes of the rate of generation of angiotensin by a reflex mechanism the efferent limb of which involves the renal nerves. The afferent pathway remains to be elucidated, but the systemic baroceptors do not appear to be of primary importance.6. The renin-angiotensin system is important in the homeostatic response to changes of blood volume. PMID- 4288207 TI - Electron microscopic quantitation of viral particles in tissues of leukemic mice. PMID- 4288208 TI - ACTH stimulation and dexamethasone inhibition in newcomers to high altitude. PMID- 4288209 TI - Implication of phospholipids in rat proximal tubule reabsorption. PMID- 4288210 TI - Electrical stimulation and metabolism of a phosphoinositide complex in the salivary gland. PMID- 4288211 TI - A micro method for performing parainfluenza virus neutralization tests. PMID- 4288213 TI - Micro-neutralization test for identification of rhinovirus serotypes. PMID- 4288212 TI - Tissue culture characteristics and oncogenicity of three SV40-induced hamster tumors. PMID- 4288214 TI - Relative effects of interferon on virus plaque formation. PMID- 4288215 TI - Early effects by SV40 on growth in vitro of hamster and human tissue cells. PMID- 4288216 TI - Characterization of two newly recognized rhinovirus serotypes of human origin. PMID- 4288218 TI - Studies on induction of virus from adenovirus and SV40 hamster tumors 2. "Helper" viruses. PMID- 4288219 TI - Virus particles in hamster tumors as revealed by electron microscopy. PMID- 4288220 TI - Identification of LSc2ab strain of type 1 poliovirus by inhibition with horse serum and dextran sulfate. PMID- 4288217 TI - Studies on induction of virus from adenovirus and SV40 hamster tumors 1. Chemical and physical agents. PMID- 4288221 TI - Effectiveness of THAM in preventing cellular damage resulting from oxygen lack. PMID- 4288222 TI - Demonstration of tissue receptors for viruses. PMID- 4288223 TI - Effect of amygdaloid lesions on pituitary-adrenal axis in the deermouse. PMID- 4288224 TI - Postcolectomy syndrome with fever and abdominal pain simulating acute abdominal inflammation caused by steroid withdrawal. PMID- 4288225 TI - Respiratory virus vaccines. IV. Heptavalent respiratory syncytial-parainfluenza mycoplasma-influenza vaccine in institutionalized persons. PMID- 4288226 TI - Respiratory virus vaccines. V. Field evaluation for efficacy of heptavalent vaccine. PMID- 4288227 TI - Studies of a biochemical lesion in experimental tuberculosis in mice. IV. Effect of tubercle bacilli grown in vivo on respiratory chain enzymes. PMID- 4288228 TI - The effects of drugs on the relation between the action potential discharge and tension in a mammalian vein. PMID- 4288229 TI - Endocrine control of freshwater tolerance in teleosts. PMID- 4288230 TI - In vitro effect of adrenocorticotropin on corticoid secretion in the turtle, snake, and bullfrog. PMID- 4288231 TI - Free radical theory of aging: free radical reactions in serum. PMID- 4288233 TI - Serological evidence of respiratory virus infections in Moscow children, 1948 to 1956. PMID- 4288232 TI - Enzyme patterns in glycogen storage disease type II (Pompe's disease). PMID- 4288234 TI - Renin, angiotensin and aldosterone in renovascular disorders. PMID- 4288235 TI - [On certain differences of the histochemistry of the endocrine pancreas of some mammals]. PMID- 4288236 TI - [Tumors of the retina and choroid with exception of retinoblastoma and malignant melanoma of the choroid]. PMID- 4288237 TI - Inorganic pyrophosphate: formation in bacterial photophosphorylation. AB - Inorganic pyrophosphate is identified as the major product of photophosphorylation by isolated chromatophores from Rhodospirillum rubrum in the absence of added nucleotides. PMID- 4288238 TI - Heat-labile serum factor required for immunofluorescence of polyoma tumor antigens. AB - The immunofluorescent demonstration of polyoma tumor antigens in tumor cells requires a heatlabile serum component. With unheated hamster tumor serum, specific fluorescence was observed in polyoma-transformed hamster, mouse, and rat tumor cells. Heated serum usually gave little or no reactivity; the activity of such heated serum could be restored simply by the addition of fresh normal unheated hamster serum. PMID- 4288239 TI - Studies on the initial phases of poliovirus reproduction cycle. PMID- 4288241 TI - Mixed malignant tumour in a digit of a dog. PMID- 4288240 TI - Hepatosplenomegaly after "cytomegalovirus mononucleosis" in a child. PMID- 4288242 TI - Substrate specificity with palladium-on-silica gel catalysts. PMID- 4288244 TI - The ecology and epidemiology of the pig-bel syndrome in man in New Guinea. PMID- 4288245 TI - Susceptibility of human diploid fibroblast strains to transformation by SV40 virus. AB - A quantitative system has been developed for the study of transformation of human diploid fibroblasts in culture by two oncogenic viruses, SV40 and the E46 strain of adeno 7-SV40 "hybrid" virus. Seven of the eleven cell strains derived from human skin biopsies when infected with SV40 (10(9) tissue culture infective doses per milliliter) gave rise to transformed colonies with approximately the same frequency (0.03 percent). Two strains derived from patients with Fanconi's anemia, an autosomal recessive disease associated with a high incidence of chromosome abnormalities and spontaneous neoplasms, gave values more than ten times higher. Two strains from persons heterozygous for this gene were also considerably more susceptible to viral transformation. PMID- 4288243 TI - Enumeration of Clostridium welchii in the faeces of varying sections of the human population. PMID- 4288246 TI - Dominant hemispherectomy: preliminary report on neuropsychological sequelae. AB - The first reported case of continuing survival 6 months after left hemispherectomy for glioma in a right-handed adult shows diminishing psychological impairment. Different degrees of initial impairment and in subsequent recovery of propositional speech, verbal comprehension, reading, writing, and other functions indicate quantitative rather than-qualitative differences in adult left-and right-hemispheric functions. PMID- 4288248 TI - Cytochemical studies in polyoma infection. I. The phosphatase group. PMID- 4288247 TI - Phosphatases in embryonic mouse cells in the course of infection with oncogenic polyoma virus. PMID- 4288249 TI - Periodate oxidation of the mucoid from horse erythrocytes. PMID- 4288250 TI - Chronic toxicity study in dogs following intralymphatic injections of ethiodol, ethiodol with chlorophyll and sterile non-iodinized poppy seed oil. PMID- 4288251 TI - Susceptibility of cultured renal cells from different species of subhuman primates to simian virus 40. PMID- 4288252 TI - Transformation of renal cells from a prosimian by simian virus 40 (SV40). PMID- 4288253 TI - Occurrence of SV40 neoplastic and antigenic information in vaccine strains of adenovirus type 3. PMID- 4288254 TI - Chlordiazepoxide and diphenylhydantoin as antagonists to ACTH effect on serum calcium and citrate levels. PMID- 4288255 TI - A high titered hemagglutinin in tissue culture prepared from Japanese B encephalitis virus. PMID- 4288256 TI - Japanese B encephalitis virus vaccines from tissue culture. VII. Formalin inactivated Nakayama strain vaccine. PMID- 4288257 TI - Increased resistance to herpes simplex virus of hamster and human cells transformed by SV40. PMID- 4288258 TI - The "critical period" for production of humorally conditioned necroses. PMID- 4288259 TI - Unique specificity of mouse angiotensinogen to homologous renin. PMID- 4288260 TI - Susceptibility of cell lines of primate and nonprimate origin to certain human viruses. PMID- 4288261 TI - Solid media with elemental sulphur for detection of sulphur-oxidizing microbes. PMID- 4288262 TI - Studies on the localization of heterologous antigenic organ and tumor extracts labelled with fluorescein isothiocyanate. PMID- 4288263 TI - The effect of atherogenic diet and superinone on the activity of certain respiratory enzymes in the livers of pigeons and white rats. PMID- 4288264 TI - Hepatic NADH-diaphorase and mitochondria in experimental traumatic shock after intralienal injection of oxygen. PMID- 4288265 TI - Central nervous system leukemia and solid tumors of childhood. Treatment with 1,3 bis (2-chloroethyl)-1-nitrosourea (BCNU). PMID- 4288267 TI - Chromosome constitution of nephroblastomas. PMID- 4288266 TI - In vitro measurements of human tumor growth. PMID- 4288268 TI - Malignant pericardial effusion secondary to metastatic breast carcinoma. A case of long-term remission. PMID- 4288270 TI - Adenosine and the adenine nucleotides. Ionization, metal complex formation, and conformation in solution. PMID- 4288269 TI - Tumors of the glomus jugulare and glomus tympanicum. PMID- 4288272 TI - The effect of beryllium chloride on rat adenohypophysis. PMID- 4288271 TI - Chemical structure of circulin A. PMID- 4288273 TI - Cytological and cytochemical studies on some organelles of the hepatic cells affected by severe intoxication with beryllium chloride. PMID- 4288274 TI - Histochemical studies on the behaviour of insulin in secreting insulomas (nesidioblastomas) of the pancreas. PMID- 4288275 TI - The relationship between ovarian tumours and intersex states with special reference to the disgerminoma and arrhenoblastoma. PMID- 4288276 TI - Defective T particles of vesicular stomatitis virus. I. Preparation, morphology, and some biologic properties. PMID- 4288277 TI - Defective T particles of vesicular stomatitis virus. II. Biologic role in homologous interference. PMID- 4288278 TI - Replication of polyoma virus in mouse embryo cells: electron microscopic observations. PMID- 4288279 TI - Rous sarcoma virus production from clones of nontransformed chick embryo fibroblasts. PMID- 4288280 TI - Mixed clones produced following infection of chick embryo cell cultures with Rous sarcoma virus. PMID- 4288281 TI - Structural changes associated with the release of enzymes from rat-liver mitochondria by freezing. PMID- 4288283 TI - Critical periods in the organization of the nervous system. Role of the adrenal hormone. PMID- 4288282 TI - ACTH effect of pituitary glands of Pacific salmon demonstrated in the hypophysectomized Couesius plumbeus. PMID- 4288284 TI - Chronic pulmonary hemodynamic recordings in nonthoracotomized unanesthetized dogs. PMID- 4288285 TI - Isolated deficiencies of anterior pituitary hormones. Symptoms and diagnosis. PMID- 4288286 TI - Left-upper-quadrant mass following trauma. PMID- 4288287 TI - Childhood malignant tumors. Concurrent chemotherapy with dactinomycin and vincristine sulfate. PMID- 4288289 TI - Erythropoietin in children. I. Findings in various types of anemia. PMID- 4288288 TI - Postural augmentation of plasma renin activity. Importance in diagnosis of renovascular hypertension. PMID- 4288290 TI - Immunochemical studies on some serological cross-reactions in the Klebsiella group. 15. Further studies on the oxidized capsular polysaccharides as antigens. PMID- 4288291 TI - Sex chromatin of trophoblastic tumors. PMID- 4288292 TI - [Trophoblastic disease of post-molar malignant aspect: conservative uterine treatment by hypogastric perfusions of methotrexate in a 20-year-old woman]. PMID- 4288293 TI - Alterations in canine liver cells induced by protein deficiency. Ultrastructural and biochemical observations. PMID- 4288295 TI - Validity of radiocarbon dates on bone. PMID- 4288294 TI - The continuous estimation of angiotensin formed in the circulation of the dog. AB - 1. The use of the rat colon as a blood-bathed organ is described for detecting changes in angiotensin concentration in the circulating blood of dogs.2. Partial occlusion of the aorta by a balloon inflated above the renal arteries leads to a contraction of the blood-bathed rat colon.3. From the experimental evidence, it is concluded that this contraction is due to an increased concentration of circulating angiotensin, brought about by the liberation of renin from the kidneys.4. The characteristics of renin release have been studied. It occurs within seconds of reducing the blood pressure to the kidneys and is proportional to the degree of reduction of blood pressure.5. With a prolonged reduction of renal blood pressure the concentration of angiotensin increases over the first 10 12 min and then reaches a stable level.6. After a small haemorrhage angiotensin often appears in the circulation without a concomitant release of catechol amines.7. Greater haemorrhages induce the secretion of catechol amines as well as of renin. The catechol amine secretion is inhibited by ganglion block, but the renin secretion is not.8. It is concluded that the secretion of renin by the kidneys in response to a fall of renal blood pressure is a physiological response, probably of importance in homoeostasis. PMID- 4288296 TI - Aldosterone secretion: differences in direct effects of rubidium and potassium perfusion into dog adrenals. PMID- 4288297 TI - Leptomeningeal sarcomata and gliomata induced in rabbits by Rous sarcoma virus. PMID- 4288298 TI - The possible involvement of an interfering substance in the action of thiosemicarbazones against viruses. PMID- 4288299 TI - The otoneurological diagnosis of intracranial expansive processes. PMID- 4288300 TI - The action of hormones on juvenile nasopharyngeal angiofibroma. A case report. PMID- 4288301 TI - Studies on the differentiation of variola and vaccinia viruses. PMID- 4288302 TI - Cytoenzymatic changes in the course of experimental osteomyelosclerosis in rats. PMID- 4288303 TI - The cytologic and cytoenzymatic differentiation of idiopathic pancytopenias and preleukemic states. PMID- 4288304 TI - Regulatory pattern of liver carbohydrate metabolizing enzymes: insulin as inducer of key glycolytic enzymes. PMID- 4288305 TI - Fetal-like patterns of lactic-dehydrogenase and aldolase isozymes in some pathological conditions. PMID- 4288306 TI - The reduction of nicotinamide N-oxide by xanthine oxidase. PMID- 4288307 TI - The activation and inactivation of phosphorylase phosphatase from bovine adrenal cortex. PMID- 4288308 TI - Brain aldehyde dehydrogenase. Localization, purification, and properties. PMID- 4288310 TI - Evidence of nuclease activities associated with the preparations of virus BAI, strain A. PMID- 4288309 TI - An examination of the cytotoxic effects of silica on macrophages. AB - Effects of silica, diamond dust, and carrageenan on mouse macrophages were studied by phase-contrast cine-micrography, electron microscopy, histochemical techniques for lysosomal enzymes and measurements of the release of lysosomal enzymes into the culture medium. All added materials were rapidly taken up into phagosomes, to which lysosomes became attached. In all cases lysosomal enzymes were discharged into the phagosomes to form secondary lysosomes. Within 24 hr most of the silica particles and enzyme had escaped from the secondary lysosomes and lysosomal enzymes were found in the culture media. Most macrophages were killed by this time. With nontoxic particles (diamond dust, aluminium-coated silica, or silica in the presence of the protective agent polyvinyl-pyridine-N oxide, PVPNO) ingested particles and lysosomal enzymes were retained within the secondary lysosomes for a much longer time, and cytotoxic effects were considerably delayed or absent altogether. It is concluded that silica particles are toxic because they are efficiently taken up by macrophages and can then react relatively rapidly with the membranes surrounding the secondary lysosomes. The particles and lytic enzymes can then escape into the cytoplasm, producing general damage, and thence into the culture medium. It is suggested that hydrogen bonding of silicic acid with lipid and protein constituents of the membrane accounts for the induced permeability. Protective agents such as PVPNO are retamed in lysosomes and preferentially form hydrogen bonds with silicic acid. Carrageenan is demonstrable within macrophages by its metachromatic reaction. It brings about release of enzymes from secondary lysosomes, but much more slowly than does silica. Silica released from killed macrophages is as cytotoxic as the original preparation. It is suggested that repeated cycles of macrophage killing in vivo leads to the mobilization of fibroblasts and fibrogenesis characterizing the disease silicosis. PMID- 4288311 TI - Regulatory mechanisms connected with RNA synthesis in avian leukaemic myeloblasts. II. Changes in enzymatic activities splitting ribonucleoside 5' triphosphates. PMID- 4288312 TI - Vesicular stomatitis virus replication in human leukocyte cultures: enhancement by phytohemagglutinin. AB - The replication of vesicular stomatitis virus in human leukocyte cultures shows that virus yields can be enhanced 6-to 180-fold by treating the leukocyte cultures with phytohemagglutinin prior to virus inoculation. Data suggest that a substance is produced in phytohemagglutinin-treated leukocyte cultures which is capable, on transfer to fresh leukocytes, of inducing blast cell formation and enhancing virus replication. PMID- 4288313 TI - Intrathoracic neurogenic tumors. PMID- 4288314 TI - [Blood coagulation disorders and carcinomas rich in mucopolysaccharides]. PMID- 4288315 TI - [Changes in the cytochrome oxidase activity in the early development of the river loach and study of the role of cell nucleus during this process]. PMID- 4288316 TI - Countercurrent distribution combined with liquid scintillation counting of double labeled water-soluble radioactive material in the study of the metabolism of steroid conjugates. PMID- 4288317 TI - The postnatal pattern of growth at the sutures of the human skull. An histological survey. PMID- 4288318 TI - Toxic effect of x-irradiated medium on chick embryo cells. PMID- 4288319 TI - Bowel perforation. A complication of peritoneal dialysis using a permanent peritoneal cannula. PMID- 4288321 TI - [Carotid body tumor]. PMID- 4288320 TI - [Nephroblastoma and neuroblastoma in older children]. PMID- 4288322 TI - Unusual localization of mixed tumours in the parotid region. PMID- 4288323 TI - Angiotensin infusion test in arterial hypertension. PMID- 4288324 TI - New instruments for infectious laryngotracheitis vaccination. PMID- 4288326 TI - Immunologic reactivity of chickens harboring Rous sarcoma. PMID- 4288325 TI - Multiplication of Rous sarcoma virus in mouse embryonal tissue. PMID- 4288327 TI - Biochemical heterogeneity of brain mitochondria. PMID- 4288328 TI - Changes in activity of certain enzymes of carbohydrate metabolism in tissue cultures infected by viruses or their infectious RNA. PMID- 4288329 TI - Cytochemical localization of two glycolytic dehydrogenases in white skeletal muscle. AB - The cytochemical localization, by conventional methods, of lactate and glyceraldehyde-3-phosphate dehydrogenases is limited, firstly, by the solubility of these enzymes in aqueous media and, secondly, by the dependence of the final electron flow from reduced nicotinamide-adenine dinucleotide (NADH) to the tetrazolium on tissue diaphorase activity: localization is therefore that of the diaphorase, which in rabbit adductor magnus is mitochondrial. NADH has been found to have great affinity to bind in the sarcoplasmic reticulum, and, therefore, if it is generated freely in the incubation media containing 2,2',5,5'-tetra-p nitrophenyl-3,3'-(3,3'-dimethoxy-4,4'-phenylene)-ditetrazolium chloride (TNBT) and N-methyl phenazonium methyl sulfate (PMS), it can bind there and cause a false staining. Since such a production of NADH can readily occur in the incubation media for glycolytic dehydrogenases due to diffusion of these soluble enzymes from tissue sections, the prevention of enzyme solubilization is extremely important. Fixation in formaldehyde prevented such enzyme diffusion, while at the same time sufficient activity persisted to allow for adequate staining. The incubation media contained PMS, so that the staining system was largely independent of tissue diaphorase activity. Application of these methods to adductor magnus of rabbit revealed by light microscopy, for both enzymes, a fine network which was shown by electron microscopy to represent staining of the sarcoplasmic reticulum. Mitochondria also reacted. These findings add further support for the notion that the sarcoplasmic reticulum is probably involved in glycolytic activity. PMID- 4288330 TI - Rate of protein biosynthesis in hepatoma 223. PMID- 4288331 TI - Quantitative behavior of acidophilic leukocytes in capillary blood of children after adrenaline and ACTH administration. PMID- 4288332 TI - Posterior rhizotomy: a possible substitute for cordotomy in otherwise intractable neuralgias of the trunk and extremities of nonmalignant origin. PMID- 4288333 TI - Anterior pituitary function. PMID- 4288334 TI - [Some data on the composition of dust in mines of the Kuznetsk Basin]. PMID- 4288335 TI - 13-C spin-rotation interaction and magnetic shielding at the carbon and oxygen nuclei in formaldehyde. PMID- 4288336 TI - Electron spin resonance of met-myoglobin: field dependence of g. PMID- 4288337 TI - Electron spin resonance of the excited triplet states of pyrimidines and purines. PMID- 4288338 TI - Luminescence and electron spin resonance studies of adenine in various polynucleotides. PMID- 4288339 TI - Phosphorescence and electron spin resonance studies of the uv-excited triplet state of DNA. PMID- 4288340 TI - [Contribution to the histochemical study of the so-called mixed tumors of the head extremity. I]. PMID- 4288341 TI - [Contribution to the histochemical study of so-called mixed tumors of the head extremity. 2]. PMID- 4288342 TI - Respiratory virus vaccines. 3. Pentavalent respiratory syncytial-parainfluenza mycoplasma pneumoniae vaccine. PMID- 4288343 TI - [Considerations on a case of malignant myoblastoma of the left cheek appearing after irradiation for basaloma]. PMID- 4288344 TI - [Action of the adrenal cortex on the glycogen level of the heart in the rat fetus and the newborn rat]. PMID- 4288345 TI - Correlation of liver cytochrome oxidase activity with mitochondrial cytochrome oxidase and phospholipid concentrations in protein-deficient rats. PMID- 4288346 TI - Metabolism of cotisol-4-C in patients with infectious and collagen diseases. PMID- 4288347 TI - [Non-defectivity of the Rous virus of the Prague strain]. PMID- 4288348 TI - Some histamine sensitizing properties of soluble preparations of the histamine sensitizing factor(HSF) from Bordetella pertussis. PMID- 4288349 TI - Relationship of interferon-like inhbitor production to Rous sarcoma virus growth and tumor formation in chicks. PMID- 4288350 TI - Neutralizing, hemagglutination-inhibiting and group complement-fixing antibody responses in human adenovirus infections. PMID- 4288351 TI - Changes in the phosphatase activity of the spinal cord motoneurons and the spinal ganglion nerve cells following axotomy. PMID- 4288352 TI - [Structure specific oxidative working of peptide-metal complexes]. PMID- 4288353 TI - A histochemical study of lactic dehydrogenase in Paget cells. PMID- 4288354 TI - Oxidation of thiocyanate, another index of thyroid function. PMID- 4288355 TI - Hormonal regulation of rat kidney transamidinase; effect of growth hormone in the hypophysectomized rat. PMID- 4288356 TI - Lipids of the BAI strain A avian tumor virus and of the myeloblast host cell. PMID- 4288357 TI - Studies on the occurrence of common specific transplantation antigens in Rous tumors of various mammalian species. PMID- 4288358 TI - Evidence for the linkage of a disaccharide to hydroxylysine in tropocollagen. PMID- 4288359 TI - The metabolism of isolated fat cells. IV. Regulation of release of protein by lipolytic hormones and insulin. PMID- 4288360 TI - Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. PMID- 4288361 TI - Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase. PMID- 4288362 TI - Phospholipid-metal complexes. Interaction of triphosphoinositide- and phosphatidylserine-metal complexes with ethylenediamine, polyaminoacids, and protein. PMID- 4288363 TI - [The hypothalamic regulation of ACTH secretion]. PMID- 4288364 TI - Experimental study on proliferation of Rous sarcoma cells and virus growth. PMID- 4288365 TI - The effect of heparin on aldosterone secretion and metabolism in primary aldosteronism. PMID- 4288366 TI - Separation and characterisation of formaldehydrogenic delta-4-3-oxo-C21-steroids by means of thin-layer chromatography on silica gel. PMID- 4288367 TI - Viral neoplastic transformation of endocrine tissues in the newborn hamster. PMID- 4288368 TI - Acquired immunologic tolerance and carcinogenesis by the mammary tumor virus. PMID- 4288369 TI - Blood pressure response to the portal infusion of angiotensin-II. PMID- 4288370 TI - Host response to homologous implantation of transformed cells. PMID- 4288371 TI - Influence of corticotrophic hormone on the secretion of gastric mucus. PMID- 4288372 TI - Heterologous transplantation of human glial tumors. PMID- 4288373 TI - Role of the pituitary and kidney in the control of adrenocortical secretion during bleeding. PMID- 4288374 TI - Possible adrenal origin of estrogens in the testicular feminization syndrome. PMID- 4288375 TI - Observations on the origin of pregnancy-associated plasma proteins. PMID- 4288376 TI - Histopathology and ultrastructure of an ovarian hilar cell tumor. PMID- 4288377 TI - Effects of E. coli endotoxemia on ventricular performance. PMID- 4288378 TI - Acute response in plasma renin and aldosterone secretion to diuretics. PMID- 4288379 TI - Effect of glucocorticoids on metabolism of carbohydrate by kidney cortex. PMID- 4288380 TI - Anaerobic CO2 production by dog kidney in vitro. PMID- 4288381 TI - Interactions between cytochrome system and H ion secretion in bullfrog gastric mucosa. PMID- 4288382 TI - [Heat denaturation of lactate dehydrogenase (L-lactate: NAD-oxidoreductase, KF 1.1.1.27) and D-glyceraldehyde-3-phosphate dehydrogenase (D-glyceraldehyde-3 phosphate: NAD-oxidoreductase, KF 1.2.1.12) from rabbit muscle]. PMID- 4288383 TI - [Electron paramagnetic resonance spectra observed during mechanical treatment of DNA preparations]. PMID- 4288384 TI - The periodic acid-Schiff reaction in neutrophil leukocytes--influence of fixation and amylase digestion. A quantitative microspectrophotometric study. PMID- 4288385 TI - The gangrene organism--a food-poisoning agent. PMID- 4288386 TI - Survival of clostridium perfringens in starch pastes. PMID- 4288387 TI - Metabolism of epitestosterone in man. PMID- 4288388 TI - Glycogen synthesis from pyruvate in muscle. PMID- 4288389 TI - [Tumors of the lacrimal glands]. PMID- 4288390 TI - Cardiac mitochondrial NADH2-cytochrome c reductase and cytochrome oxidase after cardiopulmonary by-pass in dog. PMID- 4288391 TI - The effect of denervation on respiratory enzymes in the submaxillary gland of the rat. PMID- 4288392 TI - Renal lesions induced by the simultaneous administration of angiotensin and hexadimethrine bromide. PMID- 4288393 TI - The effect of corticotrophine on free fatty acid content in rat adrenal. PMID- 4288394 TI - Neonatal herpes keratitis. PMID- 4288395 TI - Mixed systemic virus infection: a postulate for alteration of host resistance to adenovirus infection. PMID- 4288396 TI - Effect of ethanol on plasma corticosterone levels. PMID- 4288397 TI - A relatively nonspecific supersensitivity in aortic strips resulting from pretreatment with reserpine. PMID- 4288398 TI - Theophylline as a tool in studies of the role of cyclic adenosine 3',5' monophosphate in hormone-induced lipolysis. PMID- 4288399 TI - Establishment of four functional, clonal strains of animal cells in culture. AB - The single-cell plating technique was used to develop four clonal cell lines that perform organ-specific functions after being serially cultured for prolonged periods. These strains include steroid-secreting Leydig cells, melanomacells that form pigment, and two strains from a hormone-secreting rat pituitary tumor. One of the cell lines from the pituitary tumor secretes growt hormone, while another line derived from the same tumor secretes a substance similar to adrenocorticotropic hormone. PMID- 4288400 TI - [Treatment of peripheral nervous system diseases with Borislav iodobromic water]. PMID- 4288401 TI - [Malignant tumors of the brain with remittent course]. PMID- 4288402 TI - Carcinoma in situ of the lung of peripheral (bronchiolar) origin. PMID- 4288403 TI - Pulmonary blastoma, a form of carcinosarcoma. Report of a case of 24 years' duration without treatment. PMID- 4288404 TI - Pathologic examination of specimens containing nonpalpable breast cancers discovered by radiography. PMID- 4288405 TI - Histopathology of lymph nodes after lymphangiography. PMID- 4288406 TI - Treatment of trophoblastic disease. With rationale for the use of adjunctive chemotherapy at the time of indicated operation. PMID- 4288407 TI - Cryosurgical treatment of nasopharyngeal neoplasms. PMID- 4288408 TI - [Activity in vivo of cyclic 3'-5'-AMP on the ascorbic acid content of the adrenal capsules in rats]. PMID- 4288409 TI - Intermittent Cushing's syndrome with anomalous response to dexamethasone. PMID- 4288410 TI - The relationships between electrical and mechanical events in rabbit aortic strips. PMID- 4288411 TI - Centrally mediated cardiovascular effects of angiotensin II. PMID- 4288412 TI - Effect of hydrazine on liver glycogen, arterial glucose, lactate, pyruvate and acid-base balance in the anesthetized dog. PMID- 4288413 TI - The effect of hypophysectomy on canine pancreatic function. PMID- 4288414 TI - Disparity between viral growth and cellular proliferation in the hen egg chorioallantois infected with a fresh isolate of herpes simplex virus. PMID- 4288415 TI - The mechanism of host cell protein synthesis inhibition by poliovirus. PMID- 4288416 TI - Patterns of viral interference in the avian leukosis and sarcoma complex. PMID- 4288417 TI - Immunological relationships among envelope antigens of avian tumor viruses. PMID- 4288418 TI - An electron microscopic study of moderate and virulent virus-cell interactions of the parainfluenza virus SV5. PMID- 4288419 TI - Studies on foot-and-mouth disease virus ribonucleic acid synthesis. PMID- 4288420 TI - Differential effects of nucleoside analogs on L-cell macromolecular synthesis and virus growth. PMID- 4288421 TI - Effect of tannic acid on different viruses. PMID- 4288422 TI - Studies on the conditions of interferon production by cells infected with herpesviruses. PMID- 4288423 TI - Studies of infantile diarrhea in Karachi, Pakistan. I. Collection, virus isolation and typing of viruses. PMID- 4288424 TI - Venous intravasation of iodized oil during myelography. Report of a case with roentgenologic evidence of contrast medium in the iliac veins and in the lungs. PMID- 4288425 TI - Angiographic findings in a patient with tuberous sclerosis. PMID- 4288426 TI - [Persistance of the genome of the Rous virus in hamster cells converted in vitro by a non defective virus and a defective virus]. PMID- 4288427 TI - Human trichinosis: report of four cases, with emphasis on central nervous system involvement, and a survey of 500 consecutive autopsies at the Ottawa Civic Hospital. AB - In 1963, acute trichinosis was recognized in four patients at the Ottawa Civic Hospital. One presented with cavernous sinus thrombosis and sixth nerve palsy. A second had a severe systemic infection with myocarditis; the signs of myocarditis appeared in the third week. Electrocardiographic abnormalities included T-wave flattening, prolongation of PR interval and QRS complex, and non-specific changes in 25%. Central nervous system involvement occurred in the second week with general symptoms (headache, delirium and psychotic behaviour), followed in the third week by focal signs (nerve palsy, convulsion, pareses and coma).The incidence of trichinosis in the U.S.A. fell from 15.9% before 1948 to 4.5% in the period 1948-1963. The Canadian incidence in the period from 1940 to 1943 was 5.6%. In a survey in Ottawa using the Baermann digestion and compression methods, four positive cases were found out of 500 diaphragms examined. These figures indicate the success of the public health regulations aimed at controlling trichinosis. A gastrocnemius muscle biopsy is still an invaluable diagnostic tool, especially in critically ill patients with negative skin tests and no eosinophilia. PMID- 4288428 TI - Effects of thiocyanate, perchlorate and other anions on thyroidal iodine metabolism. PMID- 4288429 TI - Site of action of vasopressin in causing corticotropin release. PMID- 4288430 TI - Analysis of adenohypophysial blood flow in the rat by radioisotope washout: estimate of the vasomotor activity of vasopressin in the anterior pituitary. PMID- 4288431 TI - Histamine chromatography and electrophoresis. The omicron-phthalaldehyde fluorogram. PMID- 4288432 TI - The adsorption of metal ions on exchangers with phosphoric groups from perchloric acid solutions. PMID- 4288433 TI - A new gas-liquid chromatographic phase. PMID- 4288434 TI - Thin-layer chromatography of substituted benzaldehyde 2,4 dinitrophenylhydrazones. PMID- 4288435 TI - Quantitative determination of cholesterol in auto-oxidation mixtures by thin layer chromatography. PMID- 4288436 TI - Quantitative scanning of fluorescent or light-absorbing spots on thin-layer chromatograms. PMID- 4288437 TI - Quantitative studies on isolated pancreatic islets of mammals: enzymic hydrolysis of nucleoside diphosphates and rho-nitrophenyl phosphate in normal and cortisone treated rats. PMID- 4288438 TI - Minor epileptic status. PMID- 4288439 TI - Adaptation of variola virus to growth in the rabbit. PMID- 4288440 TI - Antibody response in guinea-pigs following intranasal inoculation of respiratory syncytial virus. PMID- 4288441 TI - [Behavior of serum enzymatic activity in the course of anesthesia in childhood surgery. 1. Alkaline phosphatase and glucose-6-phosphatase]. PMID- 4288442 TI - Use of transplantation resistance phenomenon for comparative characterization of viruses of murine leusoces. I. PMID- 4288443 TI - Adaptation to octamethyl pyrophosphoramide in rats. PMID- 4288444 TI - Study of nurse activity after removal of management functions. PMID- 4288445 TI - Aging in retardation. PMID- 4288446 TI - Head nurse on a drug addiction ward. PMID- 4288447 TI - Seclusion: a lesson for aides. PMID- 4288448 TI - Camping experiences for psychiatric patients from a day care hospital. PMID- 4288450 TI - II. Dandruff and seborrheic dermatitis. PMID- 4288449 TI - The psychiatric aide: his role and importance in a neurological (mental) hospital. PMID- 4288451 TI - Geriatrics. PMID- 4288452 TI - New knowledge, new technology demand new practice. PMID- 4288453 TI - The training of nurses in psychiatry in Paris. PMID- 4288454 TI - Motor nerve conduction velocity in chronic renal insufficiency. PMID- 4288455 TI - Insulin secreting islet cell tumors of the pancreas. PMID- 4288456 TI - Cultivating the virus of the variolovaccine in tissue culture of pancreas of Testudo graeca. PMID- 4288457 TI - The specific role of mitochondria in control of glycolysis during the development of fish embryo. PMID- 4288458 TI - Cyclic appearance of a typical mitochondria containing DNA fibers in cultures of an adenovirus 12-induced hamster tumor. PMID- 4288459 TI - The effect of x-irradiation on the nicotinamide adenine dinucleotides (NAD-NADH) content of rat thymocytes. PMID- 4288460 TI - Stress ulcers complicating myocardial infarction. PMID- 4288461 TI - Comparative effects of dihydrotachysterol-2 and dihydrotachysterol-3 in chicks. PMID- 4288462 TI - [Treatment of the climateric syndrome with conjugated estrones]. PMID- 4288463 TI - Collagenase activity of immature Fasciola hepatica. PMID- 4288464 TI - Early diffuse chromosome alterations in monkey kidney cells infected in vitro with herpes simplex virus. PMID- 4288465 TI - Biophysical studies of a rhinovirus. Ultracentrifugation and electron microscopy. PMID- 4288466 TI - Biophysical studies of a rhinovirus. Extraction and assay of infectious ribonucleic acid. PMID- 4288467 TI - Antibody responses of young infants to naturally occurring viral infections. PMID- 4288468 TI - [Histological and histochemical study of the central nervous system during neuroleptoanalgesia]. PMID- 4288469 TI - [Influence of some sympathicomimetic drugs on renal function: renographic research]. PMID- 4288470 TI - [Prevention of acute renal insufficiency in toxinfective shock treated with sympathomimetic amines. Experimental and clinical findings]. PMID- 4288471 TI - Study on the effect of flavonoids and related substances. I. The effect of quercetin on different viruses. PMID- 4288472 TI - Studies on the influence of endogenous regulatory factors on the growth of Herpes simplex virus. PMID- 4288473 TI - Chromatography of poliovirus strains isolated in Hungary prior to and after the introduction of live poliovirus vaccine. PMID- 4288474 TI - Chemical analysis of acid mucopolysaccharides of mixed salivary tumours. PMID- 4288475 TI - The role of endolymphatic radiotherapy in the treatment of chronic lymphatic leukaemia. PMID- 4288476 TI - Effects of vasomotor drugs and "mediators" of the inflammatory reaction upon the oxygen tension of tumours and tumour blood-flow. PMID- 4288477 TI - Inflammatory changes in tumour vessels after systemic 5-hydroxytryptamine, bradykinin, kallikrein, or lysolecithin. PMID- 4288478 TI - Herpes gestationis. Report on 5 cases. PMID- 4288479 TI - Localization of some enzymes in the iodonegative squamous-cell epithelium (negative Schiller area) of the cervix uteri. PMID- 4288480 TI - Antigens of leukemias induced by naturally occurring murine leukemia virus: their relation to the antigens of gross virus and other murine leukemia viruses. AB - Leukemias can be induced in W/Fu inbred rats by neonatal inoculation of normal thymus cells of C58 mice. These leukemias are not transplantable to C58 mice or to adult W/Fu rats, but they can be kept in passage in W/Fu rats aged 0 to 7 days. Adult W/Fu rats inoculated repeatedly with these isogenic leukemias produce cytotoxic and precipitating antibodies. These antisera are of particular value in the analysis of the antigens of leukemia cells and of leukemia viruses because their mode of preparation precludes the formation of antibody against any normal constituents of the cell. Analysis based on the cytotoxic test indicates the presence of 2 distinct cell surface antigens in leukemias induced by Passage A Gross virus or occurring spontaneously in mice of high-incidence strains. All leukemias and other tissues known to contain G (Gross) leukemia antigen have both determinants, but certain leukemias of low-incidence strains have only 1 of them and so were previously classified G-. Immunoprecipitation with these antisera reveals the presence of a cellular antigen common to G+ cells and absent from G- cells; the same antigen can be demonstrated in ether-treated Gross virus, but not in intact virus. This antigen is present also in ether-treated preparations of the Friend, Moloney, and Rauscher leukemia viruses, but not in Bittner (mammary tumor) virus. Thus it may be regarded as a group-specific antigen of murine leukemia viruses, in contrast to the type-specific cellular antigens demonstrable by the cytotoxic test. Four additional antigens associated with leukemias induced by wild-type Gross virus have been demonstrated by immunoprecipitation, but their relation to viral and cellular antigens has not been determined. PMID- 4288481 TI - Studies in myasthenia gravis. Short-term massive corticotropin therapy. PMID- 4288482 TI - Corticotropin in generalized myasthenia gravis. Effect of short, intensive courses. PMID- 4288483 TI - A rational approach to corticosteroid therapy for asthma in children. PMID- 4288484 TI - Investigations of enteroviruses in the aetiology of aseptic meningitis, poliomyelitis, encephalitis and other syndromes in Queensland, 1958 to 1962. PMID- 4288485 TI - Glomerular basement membrane in experimental nephrosis: chemical composition. PMID- 4288486 TI - Disorders of the peripheral motor system. PMID- 4288487 TI - Radiological and microradiographic features in a case of congenital hypophosphatasia. PMID- 4288488 TI - Metabolic requirements for infection by Rous sarcoma virus. I. The transient requirement for DNA synthesis. PMID- 4288489 TI - The effect of ultraviolet light on the infectivity and enzyme-inducing capacity of papovavirus SV40. PMID- 4288490 TI - Negative results. The urinary sodium-ACTH test for adrenal competence. PMID- 4288491 TI - [Histopathological study of Brenner tumors with special reference to the association with pseudomucinous cystadenoma and the malignant variant]. PMID- 4288492 TI - [Apropos of some malignant tumors and their lymph node metastases: microfluoroscopic study]. PMID- 4288493 TI - Nitrite reductase of Escherichia coli specific for reduced nicotinamide adenine dinucleotide. AB - Kemp, John D. (University of California, Los Angeles), and Daniel E. Atkinson. Nitrite reductase of Escherichia coli specific for reduced nicotinamide adenine dinucleotide. J. Bacteriol. 92:628-634. 1966.-A nitrite reductase specific for reduced nicotinamide adenine dinucleotide (NADH(2)) appears to be responsible for in vivo nitrite reduction by Escherichia coli strain Bn. In extracts, the reduction product is ammonium, and the ratio of NADH(2) oxidized to nitrite reduced or to ammonium produced is 3. The Michaelis constant for nitrite is 10 mum. The enzyme is induced by nitrite, and the ability of intact cells to reduce nitrite parallels the level of NADH(2)-specific nitrite reductase activity demonstrable in cell-free preparations. Crude extracts of strain Bn will also reduce hydroxylamine, but not nitrate or sulfite, at the expense of NADH(2). Kinetic observations indicate that hydroxylamine and nitrite may both be reduced at the same active site. The high apparent Michaelis constant for hydroxylamine (1.5 mm), however, seems to exclude hydroxylamine as an intermediate in nitrite reduction. In vitro activity is enhanced by preincubation with nitrite, and decreased by preincubation with NADH(2). PMID- 4288494 TI - Components required for the formation of CH-4 from methylcobalamin by extracts of Methanobacillus omelianskii. AB - Wood, J. M. (University of Illinois, Urbana), and R. S. Wolfe. Components required for the formation of CH(4) from methylcobalamin by extracts of Methanobacillus omelianskii. J. Bacteriol. 92:696-700. 1966.-Optimal conditions for the formation of CH(4) from methylcobalamin (methyl-cobalt-5,6 dimethylbenzimidazolylcobamide) by partially purified extracts of Methanobacillus omelianskii (Methanobacterium omelianskii) were achieved by the addition of two protein fractions, adenosine triphosphate, Mg(++), and a reduced flavin adenine dinucleotide-generating system. Adenosine diphosphate and adenosine monophosphate play an important role in the regulation of C(1) transfer in this reaction. The possible position of adenosine triphosphate in B(12)-dependent methyl transfer is discussed. PMID- 4288495 TI - Conversion of mevalonic acid to gamma, gamma-dimethylallyl pyrophosphate by Mycoplasma. AB - Henrikson, Carl V. (University of South Dakota, Vermillion), and Paul F. Smith. Conversion of mevalonic acid to gamma,gamma-dimethylallyl pyrophosphate by Mycoplasma. J. Bacteriol. 92:701-706. 1966.-Three representative strains of Mycoplasma, M. laidlawii strain B, Mycoplasma sp. avian strain J, and M. hominis type 2 strain O7, were examined for the presence or absence of enzymes associated with the biosynthetic pathway from mevalonic acid to gamma,gamma-dimethylallyl pyrophosphate. M. laidlawii served as a control organism, since it is capable of de novo biosynthesis of carotenoids. All four enzymes, namely, adenosine triphosphate (ATP)-mevalonate 5-phosphotransferase (EC 2.7.1.36), ATP-5 phosphomevalonate phosphotransferase (EC 2.7.4.2), ATP-5-pyrophosphomevalonate carboxy-lyase (EC 4.1.1.33), and isopentenylpyrophosphate Delta(3),Delta(2) isomerase (EC 5.3.3.2), were demonstrated in this organism. Mycoplasma sp. avian strain J, which contains all enzymes necessary for the biosynthesis of mevalonic acid, lacks the first three of the above enzymes but contains isopentenyl pyrophosphate Delta(3),Delta(2)-isomerase. M. hominis, which lacks the enzymes necessary for the biosynthesis of mevalonic acid, also is deficient in the enzymes involved in its conversion to gamma,gamma-dimethylallyl pyrophosphate. PMID- 4288496 TI - Respiration of mengovirus-infected L-929 cells. AB - Iglewski, W. J. (The Pennsylvania State University, University Park), and E. H. Ludwig. Respiration of mengovirus-infected L-929 cells. J. Bacteriol. 92:733-738. 1966.-Polarographic techniques were employed to study the oxidative metabolism of L-929 cells during a one-step mengovirus growth cycle. Virus maturation began 3.5 hr after infection and was complete with 7 hr. Virus maturation was accompanied by a decreased rate of endogenous respiration and an increased rate of oxidation of succinate and alpha-glycerophosphate by L-929 cells. The rate of glucose uptake was the same for mengovirus-infected and control L-929 cells. However, there was a decreased oxidation of glucose to carbon dioxide and a decreased production of lactic acid by L cells infected with mengovirus under aerobic conditions. Mengovirus was produced equally well under aerobic and anaerobic conditions. The implications of the alterations in metabolism with respect to virus synthesis are discussed. PMID- 4288497 TI - Multiplication of polyoma virus. II. Source of constituents for viral deoxyribonucleic acid and protein synthesis. PMID- 4288498 TI - Tumor immunity after viral oncolysis. PMID- 4288499 TI - Selective effect of pH on the production of exocellular protein by Clostridium perfringens type D. PMID- 4288500 TI - Active immunization against infection caused by B virus (herpes-virus simiae). 3. Immunoprohylaxis of inhalation infection in rabbits. PMID- 4288501 TI - Experimental infection of monkeys of the species Mac. rhesus with Pox-virus variolae and P. officinale after preimmunization with noninfectious antigen. PMID- 4288502 TI - Determination of lactic and malic dehydrogenase activity in microorganisms by means of phenazine metosulphate. PMID- 4288503 TI - Stability of the absorption patterns of poliovirus to calcium phosphate. PMID- 4288504 TI - Demyelinating neuropathy in macrocryoglobulinemia. PMID- 4288505 TI - [Experiences with iodized oil myelography]. PMID- 4288506 TI - [Histological changes in myelography with positive contrast media]. PMID- 4288507 TI - [Oral syringocarcinoma. Report of a case]. PMID- 4288508 TI - The effects of angiotensin on renal vascularity in dogs. PMID- 4288509 TI - Kinetocardiogram, phonocardiogram, and arterial pulse waves during acute hemodynamic changes. PMID- 4288510 TI - Susceptibility of goats to infectious bovine rhinotracheitis. PMID- 4288511 TI - [Sodium-potassium quotient during ACTH administration--a simple function test of the adrenal cortex]. PMID- 4288512 TI - On the role of the response of the cell membrane in determining virus virulence. Contrasting effects of the parainfluenza virus SV5 in two cell types. AB - The simian myxovirus SV5 multiplies in a continuous line of baby hamster kidney (BHK21-F) cells causing extensive cell fusion, followed by cell death. After inoculation of 15 PFU/cell, the latent period was 7 hr, the doubling time approximately 60 min, and the yield 7 PFU per cell. Giant cell formation began about 6 hr after infection and rapidly progressed to the formation by 14 to 18 hr of a single syncytium which disintegrated by 24 to 36 hr. In contrast, SV5 multiplies in primary rhesus monkey kidney cells for long periods of time producing high yields of virus with little cytopathic effect. High multiplicities of SV5 induced cell fusion in BHK21-F cells within 1 hr in the absence of virus multiplication but had no visible effect on monkey kidney cells. Time-lapse photomicrography has demonstrated that giant cells form by fusion of infected cells, and that some polykaryocytes divide. During aberrant division of polykaryocytes giant nuclei are formed from the nuclear material of several parent nuclei. The cytoplasmic development of viral antigens as demonstrated by immunofluorescence is similar in BHK21-F and monkey kidney cells. Synthesis of cellular DNA, RNA, and protein in monkey kidney cells is not shut off by SV5 infection, and in BHK21-F cells synthesis of these macromolecules is not inhibited until after extensive cell fusion has occurred 12 to 15 hr after infection. Persistently infected BHK21-F and monkey kidney cells have been serially carried through 11 and 28 cell passages, respectively. The results suggest that whether SV5 acts as a moderate virus, as in monkey kidney cells, or a virulent virus, as in BHK21-F cells, depends on the response of the cell membrane to the virus. PMID- 4288513 TI - Induction of multiple brain tumours (gliomata and leptomeningeal sarcomata) in dogs by Rous sarcoma virus. PMID- 4288514 TI - Complex formation between transition metal ions and organic solvents: electron spin resonance investigations. PMID- 4288515 TI - Effects of synthetic angiotensin on plasma free fatty acid and blood glucose levels. PMID- 4288516 TI - Action of Riley's enzyme-elevating virus on tumour-bearing mice. PMID- 4288517 TI - [Aqueous diarrhea and hypokalemia associated with a non insulin secreting Langerhansian tumor. Nosologic discussion of this syndrome with that of Zollinger and Ellison]. PMID- 4288518 TI - Etiology and pathogenesis of acquired hemolytic anemia. PMID- 4288519 TI - [A quick electrographic method for the biological detection of corticotropin]. PMID- 4288520 TI - Urinary 17-hydroxycorticosteroid excretion in guinea-pigs with hypothalamic lesions. PMID- 4288521 TI - [Influence of corticotropin on estrogen excretion in pregnancy and in intrauterine fetal death]. PMID- 4288522 TI - [On the behavior of corticosteroids in the plasma of diabetes insipidus patients during insulin hypoglycemia]. PMID- 4288523 TI - Analysis of urinary 17-ketosteroids by gas-liquid chromatography. PMID- 4288524 TI - Determination of LDH isoenzymes. PMID- 4288525 TI - Pituitary-adrenal system in rats bearing lesions in the pituitary stalk. PMID- 4288526 TI - Comparison of the responsiveness of perirenal adipose tissue of the rat, hamster, guinea pig and rabbit to the antilipolytic action of insulin. PMID- 4288527 TI - Control of epinephrine synthesis in the adrenal medulla by the adrenal cortex: hormonal specificity and dose-response characteristics. PMID- 4288528 TI - Changes in adrenal corticosterone concentration in rats: method of bio-assay for ACTH. PMID- 4288529 TI - Relationships between the structure and biological activities of corticotropin and related peptides: hyperglycemic action of N-acetylated corticotropin related peptides. PMID- 4288530 TI - Action of ACTH upon steroidogenesis in the chicken-adrenal gland. PMID- 4288531 TI - Structure and function in fructose diphosphatase. PMID- 4288532 TI - Effect of liver disease upon adrenocortical ACTH and metyrapone responsiveness in man. PMID- 4288533 TI - Leiomyoblastoma of the stomach presenting as acute intraperitoneal hemorrhage. PMID- 4288534 TI - The terminal nucleotidyltransferases of calf thymus nuclei. PMID- 4288535 TI - The pyridine nucleotide cycle and its role in the biosynthesis of ricinine by Ricinus communis L. PMID- 4288536 TI - An effect of puromycin on the synthesis of collagen by embryonic cartilage in vitro. PMID- 4288537 TI - Studies on latent infection of skin and oral mucosa in individuals with recurrent herpes simplex. PMID- 4288538 TI - Effect of morphine and nalorphine on the metabolism of phospholipids in guinea pig cerebral cortex slices. PMID- 4288539 TI - Four uncommon infections in Hodgkin's disease. PMID- 4288540 TI - Oncogenic properties of nucleic acid derived from SV-40 virus. PMID- 4288541 TI - The effect of angiotensin II on adrenal steroid synthesis in the rat. PMID- 4288542 TI - Effect of hormones on fatty acid release by rat adipose tissue in vivo. PMID- 4288543 TI - Effect of temperature on synthesis of glycogen by diaphragm muscle in vitro. PMID- 4288544 TI - Dissociation of the acute secretions of thyrotropin and adrenocorticotropin. PMID- 4288545 TI - Effect of anthrax toxin on oxidative metabolism of lung tissues. PMID- 4288546 TI - Mycoplasma and adenovirus pneumonias. Comparison with other atypical pneumonias in a military population. PMID- 4288547 TI - Extended study of Serratia in a diagnostic bacteriology laboratory. PMID- 4288548 TI - Lymphatic cysts of the mesentery. PMID- 4288549 TI - Induction of dihydrofolate reductase activity by SV40 and polyoma virus. PMID- 4288550 TI - DNA synthesis and neoplastic transformation in rat liver parenchyma. PMID- 4288551 TI - Chemical, enzymatic, and cytochrome assays of microsomal fraction of hepatomas with different growth rates. PMID- 4288552 TI - The metabolism of 4-nitroquinoline-1-oxide, a carcinogen. 3. An enzyme catalyzing the conversion of 4-nitroquinoline-1-oxide to 4-hydroxyaminoquinoline-1-oxide in rat liver and hepatomas. PMID- 4288553 TI - Immunology of spontaneous mammary carcinomas in mice. V. Acquired tumor resistance and enhancement in strain A mice infected with mammary tumor virus. PMID- 4288554 TI - Equine infectious anemia. New problems. PMID- 4288555 TI - The introduction of anti-Rous sarcoma virus activity and chick embryo cell toxicity into human sera during processing. PMID- 4288556 TI - Morphology and development of some murine leukemia viruses. PMID- 4288557 TI - A virus-induced rhabdomyosarcoma of mice. PMID- 4288558 TI - Tissue culture and serologic studies of mouse leukemia viruses. PMID- 4288559 TI - Association of enzymes: adenosinetriphosphatase and alkaline phosphatase with the virions of murine leukemias. PMID- 4288560 TI - Murine leukemia viruses: rupture with ether and detergents to subviral constituents. PMID- 4288561 TI - Experiments on the hematologic diversification of viral mouse leukemias. PMID- 4288562 TI - Studies on leukemia in mice associated with a transplantable methylcholanthrene induced hepatoma. PMID- 4288563 TI - Infective and noninfective viral murine leukemias. PMID- 4288564 TI - Are the common forms of spontaneous and induced leukemia and lymphomas in mice caused by a single virus? PMID- 4288565 TI - Murine leukemia and its viruses. PMID- 4288566 TI - Serological analysis of leukemia antigens of the mouse. PMID- 4288567 TI - Further studies on the biological relationship of murine leukemia viruses and on kidney lesions of mice with leukemia induced by these viruses. PMID- 4288568 TI - Lymphoid tumor induction by mouse thymocytes infected in vitro with radiation leukemia virus. PMID- 4288569 TI - Some experimental evidence for the influence of genetic factors on viral leukemogenesis. PMID- 4288570 TI - The histocompatibility-2 locus and susceptibility to tumor induction. PMID- 4288571 TI - Leukemia virus release in chemically or physically induced lymphomas in BALB-c mice. PMID- 4288572 TI - Inhibition of virus-induced leukemia in mice by a nontumor virus. PMID- 4288573 TI - Origin of the viremia in murine leukemia. PMID- 4288574 TI - Masculinization in pregnancy. Report of a case. PMID- 4288575 TI - ACTH and steroids: their use in the practice of allergy. PMID- 4288576 TI - Hypertension, increased aldosterone secretion and low plasma renin activity relieved by dexamethasone. AB - A father and son are described with a condition characterized by benign hypertension, potassium deficiency, increased aldosterone secretion rate (ASR), raised plasma volume and suppressed plasma renin activity (PRA). There were intermittent elevations of urine 17-ketosteroids and 17-hydroxycorticoids (17 OHCS) but no increase in urine THS, normal circadian rhythm of plasma 17-OHCS, and normal urine 17-OHCS response to dexamethasone and intravenous ACTH. Plasma ACTH and corticosterone secretion were not elevated. Pregnanetriol excretion was normal but urine pregnanediol was increased. At operation on the father no adrenal tumour was found; the excised left adrenal weighed 7 g. and showed nodular cortical hyperplasia; juxtaglomerular cells showed only occasional granules. Following operation hypertension persisted and ASR was half the preoperative value. All abnormalities in father and son were relieved by dexamethasone (DM) 2 mg. daily. The condition recurred following cessation of DM but was relieved by a second course of treatment. No such response to DM was seen in a normal subject or in a patient with Conn's syndrome. For a number of reasons it is suggested that patients with hypertension, increased ASR and low PRA be given a trial of dexamethasone treatment before undergoing adrenal surgery. PMID- 4288577 TI - Odontodysplasia. Report of three cases. PMID- 4288578 TI - An analysis of SV40-induced transformation of hamster kidney tissue in vitro. 3. Persistence of SV40 viral genome in clones of transformed hamster cells. PMID- 4288579 TI - An analysis of SV40-induced transformation of hamster kidney tissue in vitro. IV. Studies of the pathology of hamster tumors induced with SV40-transformed hamster cell clones. PMID- 4288580 TI - Morphological and virological investigations on cultured Burkitt tumor lymphoblasts (strain Raji). PMID- 4288581 TI - Chemotherapy in the treatment of leukemia and Wilms' tumor. PMID- 4288582 TI - Differential metabolic activity in Paget's cells and associated epithelia of the vulva. PMID- 4288583 TI - [Clinically observed side-effects of recent antibiotics. Novobiocin--polymyxin]. PMID- 4288584 TI - [Role of the nervous system in allergic-anaphylactic processes. 3. Personal studies on "nervous system and anaphylaxis"]. PMID- 4288585 TI - A long-term study of sarcoid and its modification by steroid therapy. Lung function and other factors in prognosis. PMID- 4288586 TI - The pharmacology of pressor drugs. PMID- 4288587 TI - An evaluation of the perchlorate discharge test. PMID- 4288588 TI - Specificity of the "tibia test" in intact immature female rats. PMID- 4288589 TI - Granular-cell myoblastoma of the bronchus. Report of a case. PMID- 4288590 TI - Laser action at the cellular level. PMID- 4288591 TI - Protective effect of antibody to parainfluenza type 1 virus. PMID- 4288592 TI - Changes in lymph node size induced by lymphangiography. PMID- 4288593 TI - Enhanced growth of human embryonic cells infected with adenovirus 12. AB - Fibroblast-like cells from human embryonic lung were infected with adenovirus type 12, and they survived as an established line, with the characteristics of "transformation" following considerable cellular killing. Inclusion bodies disappeared and cells became resistant to reinfection with type 12 virus as they grew in thick multilayered strands, and giant and syncytial cells became commonplace. An induced new cell antigen demonstrable by complement-fixation and fluorescent-antibody studies persisted for at least 20 culture passages after infection. PMID- 4288594 TI - Zollinger-Ellison syndrome with interesting variations. Report of twelve cases including one of carcinoid of the duodenum. PMID- 4288595 TI - Lobar cirrhosis with nodular hyperplasia (hamartoma) of the liver treated by left hepatic lobectomy. PMID- 4288596 TI - Immunology of the mouse mammary tumor virus. Correlation of the immunodiffusion precipitate line with type-B virus particles. PMID- 4288597 TI - Response of cultured chicken brain neuroglial cells to infection with Rous sarcoma virus. PMID- 4288598 TI - Carcinogenic activity of analogues of p-dimethylaminoazobenzene. V. Effect of added methyl groups in the pyridine series. PMID- 4288599 TI - [Loganiaceae of the Ivory Coast. 3. Alkaloids of Strychnos splendens Gilg.: isolation and structure of strychnosplendine]. PMID- 4288600 TI - Cytopathologic changes in fowlpox (turkey origin) inclusion body formation. PMID- 4288601 TI - Tissue concentration differences during active transport of calcium by intestine. PMID- 4288602 TI - Experimental respiratory infection with poxviruses. I. Clinical virological and epidemiological studies. PMID- 4288603 TI - Experimental respiratory infection with poxviruses. II. Pathological studies. PMID- 4288604 TI - An investigation of the incidence, epidemiology and control of Simian virus 5. PMID- 4288605 TI - Oxygen uptake by Clostridium welchii type A: its possible role in experimental infections in passively immunised animals. PMID- 4288606 TI - [Adaptation of permanent cell strains cultivated in a lactalbumin hydrolysate medium in various culture media]. PMID- 4288607 TI - Hypophosphatasia. PMID- 4288608 TI - Exaltation of the development of poliovirus by semicarbazide. AB - Grossberg, Sidney E. (Institut Pasteur, Paris, France), Marguerite Lwoff, and Andre Lwoff. Exaltation of the development of poliovirus by semicarbazide. J. Bacteriol. 92:1473-1477. 1966.-Semicarbazide (NH(2)-NH-CO-NH(2)) remarkably increases the development of poliovirus. In single-cycle experiments, semicarbazide (SCZ) acted to (i) diminish the length of the latent period, (ii) increase the rate of production of virions, and (iii) increase the final yield of virus. These effects were demonstrable in KB cells, a human malignant cell line, and other primate cells. The dose range over which the compound exerts its effect was relatively large, i.e., from 0.3 to 20 mm, whereas higher concentrations inhibited viral growth. SCZ achieved its exalting effect only when it was added during the first 3 hr of viral development; later addition had no effect. Withdrawal of SCZ at intervals during the viral cycle confirmed that its action occurred within 3 hr after infection. The possible mode of action of SCZ is discussed. SCZ appeared to act, at least in part, by increasing the rate of synthesis of the viral ribonucleic acid. PMID- 4288609 TI - Reaction of endotoxin and surfactants. I. Physical and biological properties of endotoxin treated with sodium deoxycholate. AB - Ribi, E. (Rocky Mountain Laboratory, Hamilton, Mont.), R. L. Anacker, R. Brown, W. T. Haskins, B. Malmgren, K. C. Milner, and J. A. Rudbach. Reaction of endotoxin and surfactants. I. Physical and biological properties of endotoxin treated with sodium desoxycholate. J. Bacteriol. 92:1493-1509. 1966.-Endotoxins from three species of gram-negative bacteria were shown to be dissociated by the bile salt sodium deoxycholate (NaD) into nontoxic subunits with molecular weights of about 20,000. When the bile salt was removed by dialysis, the subunits reaggregated in an orderly manner to form a relatively uniform population of biologically active endotoxin particles with average molecular weights of 500,000 to 1,000,000. If a small amount of human plasma was added to the dissociated endotoxin before removal of the NaD, reassociation apparently did not occur and the preparation remained nonpyrogenic. However, the plasma protein could subsequently be removed from the endotoxin subunits, and reaggregation to the toxic form would then occur. The studies on the physical nature of endotoxin performed with biophysical solution techniques were supplemented and confirmed by direct examination of the endotoxin polymers by electron microscopy. The results of these studies were consonant with the theory that the biologically active endotoxic elements are composed of micellar aggregates of linear lipopolysaccharide subunits. PMID- 4288610 TI - Correlation between infectivity and physical virus particles in human cytomegalovirus. AB - Benyesh-Melnick, Matilda (Baylor University College of Medicine, Houston, Tex.), Fern Probstmeyer, Robert McCombs, Jean P. Brunschwig, and Vladimir Vonka. Correlation between infectivity and physical virus particles in human cyto megalovirus. J. Bacteriol. 92:1555-1561. 1966.-Infectivity titers [measured as plaque-forming units (PFU)] and particle counts by the sedimentation pseudo replication technique were determined for crude, unpurified, intracellular preparations of two different strains of human cytomegalovirus. Unlike the high particle-infectivity ratio of 10(6) to 10(8) previously reported for these viruses, the number of total particles per PFU ranged from 160 to 490 with strain AD-169 and from 176 to 1,050 for strain C-87. Interpretation of particle-PFU ratios of intracellular cytomegalovirus in terms of particle morphology is not conclusive at this time. The number of enveloped forms found varied between 0 and 34% of the total particles counted. However, the true proportion is probably greater, because envelopes were found to be destroyed by the enzyme treatment used in preparing the specimens for examination in the electron microscope. The number of full particles found ranged between 4 and 31% of the total particles counted. The particle per PFU ratio of extracellular virus was found to be three- to fivefold lower than that of intracellular virus. PMID- 4288611 TI - Estrogen therapy in inhibition of growth. PMID- 4288612 TI - Cushing's syndrome due to bilateral adrenocortical hyperplasia caused by a benign adrenal medullary tumor. PMID- 4288613 TI - Metabolic clearance rate and blood production rate of testosterone and androst-4 ene-3,17-dione under basal conditions, ACTH and HCG stimulation. Comparison with urinary production rate of testosterone. PMID- 4288614 TI - An analysis of factors determining the circadian pattern of aldosterone excretion. PMID- 4288615 TI - Effect of corticosteroids on the cardiovascular responses to angiotensin and norepinephrine. PMID- 4288616 TI - Atrophy of laryngeal muscles in vagal paralysis. PMID- 4288617 TI - [On a case of granulocellular tumor of the cheek]. PMID- 4288618 TI - [Preparation of concentrated foot-and-mouth disease antigen on cell culture for the study of 3 "O" type variants: O Flanders--O Sicily 58--O Spain 64]. PMID- 4288619 TI - Role of ingredients in alginate impression compounds. PMID- 4288620 TI - [The use of selective hypothermia in the prevention of renal damage caused by acute ischemia. Study of phosphatase activity]. PMID- 4288621 TI - The effect of host age, virus dose and route of inoculation on inapparent infection in mice with Japanese encephalitis virus. PMID- 4288622 TI - Effect of diabetogenic hormones on transport of glucose in small intestine in vitro. PMID- 4288623 TI - Growth and cytopathic effect of H type rhinoviruses in monkey kidney tissue culture. PMID- 4288624 TI - BAI strain A avian (myeloblastosis) leukosis virus from myeloblast tissue culture. PMID- 4288625 TI - Hyperresponsivity to angiotensin induced in rats by behavioral stimulation. PMID- 4288626 TI - The need for calcium in adrenomedullary secretion evoked by biogenic amines, polypeptides, and muscarinic agents. PMID- 4288627 TI - Comparison of two different transplantable mammotropic pituitary tumors. Hormone content and effect on host. PMID- 4288628 TI - Effects of cortisol on interferon production by mouse peritoneal leukocytes and spleen in vitro and in vivo. PMID- 4288629 TI - Diuretic effect of angiotensin in the chicken. PMID- 4288630 TI - Multiple enzyme determinations in sera and livers of tumor bearing hamsters. PMID- 4288631 TI - Bone formation in normal and vitamin D-treated rachitic rats during the administration of polyphosphates. PMID- 4288632 TI - In vitro inhibition of intestinal fluid and electrolyte transfer by a non-beta islet cell tumor. PMID- 4288633 TI - Effect of 8-azaguanine on encephalomyocarditis virus multiplication. PMID- 4288634 TI - Enhancement of polio-RNA infectivity by dimethylsulfoxide. PMID- 4288635 TI - Viral pollution of shellfish. 1. Some basic facts of uptake. PMID- 4288636 TI - Antiviral activity of N1-furfurylbiguanide hydrochloride (FFB) in vitro. PMID- 4288637 TI - An interferon-like viral inhibitor in body fluids of endotoxin-injected rabbits. PMID- 4288638 TI - Induction of neoplasia in vitro in hamster thyroid tissue by SV40 and adenovirus 7-SV40 "hybrid" (STRAIN LLE46). PMID- 4288639 TI - The Virus Watch program. IV. Recovery and comparison of two serological varieties of adenovirus type 5. PMID- 4288640 TI - Comparison of intestinal absorption and esterification of 4-C14 vitamin D3 and 4 C14 cholesterol in the rat. PMID- 4288642 TI - Simultaneous and combined vaccination against Newcastle disease and fowl pox. PMID- 4288641 TI - Prevention and interruption of SV40 induced transplantation immunity with tumor cell extracts. PMID- 4288643 TI - Gross and microscopic lesions in the nasopharynx of pigs with Aujeszky's disease. PMID- 4288644 TI - Determination of virus content, and possible diagnostic value of organs from pigs died of Aujeszky's disease. PMID- 4288645 TI - Neurological presentations of insulin secreting tumours of the pancreas. PMID- 4288646 TI - [Experiences with a hemostatic of estrogen basis in the tooth and jaw region]. PMID- 4288647 TI - The in vitro determination of the D antigens of poliomyelitis viruses. I. The gel diffusion tes. PMID- 4288648 TI - Virus specific antigens in mammalian cells infected with herpes simplex virus. PMID- 4288649 TI - A study of the reaction of glyceraldehyde with glyceraldehyde 3-phosphate dehydrogenase. PMID- 4288650 TI - Serine biosynthesis in rat liver. Regulation of enzyme concentration by dietary factors. PMID- 4288651 TI - Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. 3. Cytidine diphosphate D-glucose oxidoreductase. PMID- 4288652 TI - Mixed function oxidation. VI. Purification of a tightly coupled electron transport complex in camphor lactonization. PMID- 4288653 TI - Peripheral neuropathy following tetanus toxoid administration. PMID- 4288654 TI - Studies of some substances with antiviral activity. 3. The inhibition of poliovirus type 1 and 2 induced cytopathogenic changes in cell cultures of human embryonic kidneys by derivatives of thiazolidine acetic acid. PMID- 4288655 TI - Duration of cytomegaloviruria in nursery children. PMID- 4288656 TI - Studies on the molecular mechanism of the radioprotective effect of serotonin. PMID- 4288657 TI - Free radical formation in amino acids exposed to thermal hydrogen atoms. PMID- 4288658 TI - The radiation sensitivity of normal and polyoma-transformed rat embryo cells. PMID- 4288659 TI - Experience with a selective medium in the routine diagnosis of gonorrhoae, with special regard to rectal gonorrhoae in women. PMID- 4288660 TI - Ossification sequence polymorphism and sexual dimorphism in skeletal development. PMID- 4288661 TI - Cryosurgery of the pituitary in acromegaly: reduced growth hormone levels following hypophysectomy in 13 cases. PMID- 4288662 TI - [Pathological anatomy of adenoviral diseases of the lungs in children]. PMID- 4288663 TI - [Mechanism of the ACTH effect on the adrenal cortex]. PMID- 4288664 TI - The effect of metal ions on free radical formation and reactions in irradiated proteins. PMID- 4288665 TI - Odontodysplasia. PMID- 4288666 TI - Mediastinal lymph node visualization by lymphography. Report of a case. PMID- 4288667 TI - Nobel Prize. PMID- 4288668 TI - Effects of actinomycin D on avian myeloblast and BAI strain A virus RNA synthesis in vitro. PMID- 4288669 TI - Ultrastructural alterations in avian leukemia myeloblasts exposed to actinomycin D in vitro. PMID- 4288670 TI - Hepatic carcinogenesis in thyroidectomized rats: apparent blockade at the stage of initiation. PMID- 4288671 TI - Nucleic acid interactions. A molecular approach to the study of genes and their products. PMID- 4288672 TI - Neoplastic transformation. PMID- 4288673 TI - [ACTH treatment of multiple sclerosis]. PMID- 4288674 TI - Implantation of the rat embryo: glycogen and alkaline phosphatases. PMID- 4288675 TI - Failure of orally administered perchlorate to affect deciduoma formation or pregnancy in the rat. PMID- 4288676 TI - The incidence of spontaneous deciduomata in pseudopropregnant rats. PMID- 4288677 TI - Fatal hepatic and bronchial necrosis in adenovirus infection with thymic alymphoplasia. PMID- 4288678 TI - Thiamine pyrophosphate hydrochloride: stereochemical aspects from an x-ray diffraction study. AB - The crystal structure of thiamine pyrophosphate has been determined by a three dimensional x-ray analysis. The conformation of the molecule in the crystalline state is determined by the formal charge distribution within the molecule which exists as a zwitterion with the negative pyrophosphate chain folded back over the positive, ring portion of the molecule. The oxygen atoms in the pyrophosphate group are in the staggered conformation when viewed along the phosphorus phosphorus axis. Even though the pyrophosphate is present in this compound as the monoionized monoester, the configuration is the same as that present in the inorganic pyrophosphate ion. From a comparison of three different crystal structures containing the thiamine moiety and from studies with atomic models, it seems plausible that the basic molecular conformation observed in this crystal is maintained in the catalytically active molecule. Knowledge of the detailed crystal structure provides new insight into the biochemical mechanism of reactions catalyzed by thiamine pyrophosphate. PMID- 4288679 TI - Feedback inhibition of key glycolytic enzymes in liver: action of free fatty acids. AB - Increasing concentrations of sodium octanoate were progressively inhibitory to the activities of glucokinase, hexokinase, phosphofructokinase, and pyruvate kinase. Glucose-6-phosphate and 6-phosphogluconate dehydrogenases were also markedly inhibited. Other enzymes of carbohydrate metabolism such as lactate dehydrogenase, phosphohexose isomerase, and fructose-1,6-diphosphatase were not decreased. Among the key glycolytic enzymes, the inhibition of pyruvate kinase by the fatty acid was most marked. The biological significance of the inhibition of the key glycolytic enzymes is interpreted as a feedback inhibitory mechanism in regulation of fatty acid biosynthesis. The mechanism may function for rapid adaptation by which the organism can use the fatty acid level as a metabolic directional switch in decreasing glycolysis and turning on gluconeogenesis. PMID- 4288680 TI - [Histo-enzymologic research on the metabolism of glucides. I. Phosphorylase and oxidoreduction enzymes in the cerebellum of mammals]. PMID- 4288681 TI - [Effect of RNA preparations on the growth of transplanted hepatomas in vivo and on protein synthesis in tumor cells in vitro]. PMID- 4288682 TI - [Isolation of an acid-insoluble ribopolynucleopeptide from animal cells]. PMID- 4288683 TI - Insulin-secreting islet-cell tumour of the pancreas. PMID- 4288684 TI - Renal angiotensinase activity. Its localization and the effects of mercury. PMID- 4288685 TI - Effect of adrenergic antagonists on the peripheral constrictor action of kinekard, a cardioactive plasma fraction. PMID- 4288686 TI - Potentiation of vascular myotropic responses by metanephrine and other noncatecholamines. PMID- 4288687 TI - Release of adrenal catecholamines by angiotensin. II. PMID- 4288688 TI - Contraction of vascular smooth muscle in response to plasma. Comparison with response to known vasoactive agents. PMID- 4288689 TI - The experimental production of ischemic facial paralysis. PMID- 4288690 TI - Evaluation of ACTH reserve in pituitary-hypothalamic disease. PMID- 4288691 TI - Reserpine in experimental cerebral edema. PMID- 4288692 TI - [Etiology, clinical aspects and treatment of epidemic keratoconjunctivitis]. PMID- 4288693 TI - Potentiation of SV40 replication in human cells by adenovirus 4. PMID- 4288694 TI - Surgical intervention during chemotherapy of gestational trophoblastic neoplasms. PMID- 4288695 TI - Ultrastructure of human primary hepatic carcinoma. PMID- 4288696 TI - Histochemical studies of the juxtaglomerular apparatus of the kidney of a white rat. PMID- 4288697 TI - [A review of the present knowledge of the renin-angiotensin-aldosterone system]. PMID- 4288698 TI - Certain aspects of adrenocortical function and carbohydrate--lipid metabolism in obese patients. 3. Pituitary--adrenal reserve in obese persons. PMID- 4288699 TI - Cyclic hormonetherapy. A report on 305 cases. PMID- 4288700 TI - Immunopathology of NZB/BL mice. V. Viruslike (filtrable) agent separable from lymphoma cells and identifiable by electron microscopy. AB - A filtrable agent separable from transplantable malignant lymphomas of NZB/Bl mice was capable, upon inoculation into preweanling NZB/Bl mice, of inducing lymphoid cell hyperplasia, hypergammaglobulinemia, proteinuria, hypoalbuminemia, and pathological changes (focal membranous glomerulonephritis) of kidneys-renal functional and structural changes qualitatively similar to those of spontaneous occurrence in older NZB/Bl mice. Viruslike particles with close resemblance to the typical "C" type murine oncogenic virus particles were identified by means of electron microscopy in NZB/Bl mouse tissues and cells, including malignant lymphoma cells, benign lymphoid cells of thymus and spleen, epithelial cells of renal tubules, and extracellular sites. The relevance of these observations, the first of their kind dealing with NZB/Bl mice, is discussed in relation to the several immunopathological disorders which characterize this strain of mice. PMID- 4288701 TI - Studies on the heterologous immunogenicity of a methanol-insoluble fraction of attenuated tubercle bacilli (BCG). II. Protection against tumor isografts. AB - A methanol-insoluble residue (MER) of phenol-killed attenuated tubercle bacilli (BCG), which has been reported previously to be capable of evoking heightened resistance to infection with antigenically unrelated microorganisms, was found to affect as well the resistance of highly inbred mice against tumor isografts. In most instances, the MER evoked heightened resistance against the tumor implants, but heightened susceptibility was the effect induced against two of the tumors tested, and no effect was elicited against one neoplasm. It is suggested that the heightened susceptibility occasionally produced by pretreatment with MER may also be of immunological nature, i.e. immunological enhancement. Treatment with MER was more effective when administered some time before tumor challenge than when given simultaneously with, or after, tumor implantation. The protective effects manifested against some tumors were of a high order, a significant number of animals rejecting the neoplastic implants, and were displayed even when several months elapsed between treatment and challenge. Living BCG and intact phenol killed bacilli also evoked heightened resistance against some of the tumors tested, and in one experiment living BCG proved effective whereas MER did not. On the whole, however, MER was the most active (and least toxic, as shown previously) of the several tubercle bacillus preparations tested. MER elicited heightened reactivity against first transplant generation tumors as well as against tumors maintained for considerable periods of time by repeated animal passage, and against spontaneously arising as well as against induced neoplasms. The experimental parameters necessary to demonstrate maximal effects varied somewhat from tumor to tumor. In general, however, single intraperitoneal injections of small quantities of MER, of the order of 0.25 to 1.0 mg, afforded the best protection. PMID- 4288702 TI - [Studies on the ecology of enterovirus, especially poliovirus after the vaccination with live attenuated poliovaccines]. PMID- 4288703 TI - Role of newborn monkeys in the study of viral oncogenesis. PMID- 4288704 TI - [The effect of steroid therapy on the acute and convalescent period of trichinellosis. I. The effect of steroid therapy on the edema, fever, and myalgia period and total duration of the disease]. PMID- 4288705 TI - [The effect of cortisone and ACTH upon the intensity of trichinella invasion in animals]. PMID- 4288706 TI - Inactivation and induction of electron spin resonance-centres in trypsin by ionizing radiation and by ultra-violet light. PMID- 4288707 TI - Incompatibility of synthetic tetraicosapeptide corticotrophin with the present USP and International Corticotrophin Standard. PMID- 4288708 TI - [On the anti-stress activity of vitamin C]. PMID- 4288709 TI - [Idiopathic hypotension. Pharmacological tests and therapeutic success with a pressure suit]. PMID- 4288710 TI - [Changes in the ATP content in liver tissue of the mouse in experimental virus MHV-3-hepatitis]. PMID- 4288711 TI - Effect of ethanol on ethylene glycol oxidation by mammalian liver enzymes. PMID- 4288712 TI - Histomonas meleagridis and several bacteria as agents of infectious enterohepatitis in gnotobiotic turkeys. PMID- 4288713 TI - Cytology and cytochemistry of the chemoreceptor cell in man. PMID- 4288714 TI - A diurnal rhythm in plasma renin activity in man. PMID- 4288715 TI - Glucose, insulin, and triglyceride responses to high and low carbohydrate diets in man. PMID- 4288716 TI - Urological spectrum of adrenal surgery. PMID- 4288717 TI - [The place of viruses in the etiology of acute appendicitis in childhood]. PMID- 4288718 TI - [Traumatic deciduomas after short term progesterone preparation in rats]. PMID- 4288719 TI - [Studies on the effect of polyoma virus on host cells. Biologic, metabolic and pathologic aspects of infection of cells and their transformation to tumor cells]. PMID- 4288720 TI - Virulence and immunogenicity in mice of airborne encephalomyocarditis viruses and their infectious nucleic acids. PMID- 4288721 TI - Steroid nephropathy. A case of renal disease showing similar changes of lipoid nephrosis modified by steroid treatment. PMID- 4288722 TI - Enzyme histochemistry of human brain tumors and their tissue cultures with special reference to the oxidoreductases in the glioblastoma multiforme. PMID- 4288723 TI - Control of glycolysis in the human red blood cell. PMID- 4288724 TI - Enhancing effect of nucleic acids and their derivatives in the reduction of cytochrome c by ferrous ions. PMID- 4288725 TI - Electron transport systems of the chemoautotroph Ferrobacillus ferrooxidans. II. Purification and properties of a heat-labile iron-cytochrome c reductase. PMID- 4288726 TI - Differential effects of mercurial on the lipoyl reducatase and diaphorase activities of lipoyl dehydrogenase. PMID- 4288727 TI - The incorporation of nucleotides into amino acid transfer ribonucleic acid. 3. Thincorporaton of uridylic acid. PMID- 4288728 TI - Effect of adrenocorticotropin and other hormone preparations upon the metabolism of acetate-1-14C and other 14C-labeled substrates by adipose tissue in vitro. PMID- 4288729 TI - The role of transfer ribonucleic acid in the pyrophsphate exchange reaction of arginine-transfer ribonucleic acid synthetase. PMID- 4288730 TI - The neuropathology of encephalitis Japonica in humans especially from subchronic to chronic stage. PMID- 4288731 TI - The diagnosis of Japanese encephalitis by means of fluorescent antibody technique in autopsy cases. PMID- 4288732 TI - An electron microscopic study on the fine structures of cerebral cortex in the mice infected with Japanese encephalitis virus. PMID- 4288733 TI - Paget's carcinoma of larynx. PMID- 4288734 TI - The induction of hepatitis by prior partial hepatectomy in resistant adult rats injected with H-1 virus. Light and electron microscopy and virologic studies. PMID- 4288735 TI - The combined effect of monoamine oxidase inhibitors and corticosteroids on the pituitary-gonadal system of male rats. PMID- 4288736 TI - Experimentallly induced hyperfunction of the pituitary-adrenal zona fasciculata system in the rat. PMID- 4288737 TI - The effect of adenohypophysectomy on the extrarenal and renal excretion of the saline-loaded duck(Anas platyrhynchos). PMID- 4288738 TI - The role of plasma free fatty acids in the elevation of plasma cholesterol and phospholipids produced by adrenaline. PMID- 4288739 TI - [Experience with ozocerite in the treatment of diseases of the peripheral nervous system at the Truskavets health resort]. PMID- 4288740 TI - Inactivation of viruses by benzalkonium chloride. AB - Benzalkonium chloride (as Roccal or Zephiran) was found to inactivate influenza, measles, canine distemper, rabies, fowl laryngotracheitis, vaccinia, Semliki Forest, feline pneumonitis, meningopneumonitis, and herpes simplex viruses after 10 min of exposure at 30 C or at room temperature. Poliovirus and encephalomyocarditis virus were not inactivated under the same conditions. It was concluded that all viruses tested were sensitive except members of the picorna group. The literature was reviewed. PMID- 4288741 TI - [Heat-resistance of Cl. welchii as normal flora in the human intestine]. PMID- 4288742 TI - [Erythropoietic changes in Friend leukemia of mice]. PMID- 4288743 TI - [The effect of adrenalectomy, ACTH and hydrocortisone on the development of experimental stomach ulcers]. PMID- 4288744 TI - [Artificial heterogenization of malignant tumors: the 2d principle of immunological treatment of neoplasms]. PMID- 4288745 TI - [The effect of ascitic fluid on the adhesion of ascitic tumor cells and L-strain fibroblasts to glass]. PMID- 4288746 TI - Hepatic gluconeogenic enzymes, RNA metabolism and amino acid levels in rats carrying transplantable growth hormone-secreting pituitary tumors. PMID- 4288747 TI - The influence of pH on the apparent oxidation-reduction potential of heart muscle succinic dehydrogenase. PMID- 4288748 TI - Mammalian alpha-keto acid dehydrogenase complexes. I. Isolation, purification, and properties of pyruvate dehydrogenase complex of pig heart muscle. PMID- 4288749 TI - Bacterial degradation of biotin. Catabolism of 14C-biotin and its sulfoxides. PMID- 4288750 TI - Studies on dihydronicotinamide adenine dinucleotide ubiquinone reductase. I. Assay of ubiquinone reductase activity in submitochondrial particles and extracts. PMID- 4288751 TI - Effect of purines on epinephrine-induced lipolysis in adipose tissue. PMID- 4288752 TI - Measurement of guanosine 3',5'-monophosphate and other cyclic nucleotides. Variations in urinary excretion with hormonal state of the rat. PMID- 4288753 TI - [Study of the phosphodiesterase activity of saprophytic bacteria]. PMID- 4288754 TI - [Therapeutic results in 45 cases of apparently extra-globular, acquired hemolytic anemia]. PMID- 4288755 TI - A roentgenographic analysis of respiratory syncytial virus pneumonia in infants. PMID- 4288757 TI - "Pig-bel": clostridial food poisoning. PMID- 4288756 TI - Effect of essential fatty acids deficiency upon the lipidic composition and enzymatic activity of rat mitochondria. PMID- 4288758 TI - Fibro-angioma of the facial nerve. PMID- 4288760 TI - [Determination and evaluation of angiotensin. II]. PMID- 4288759 TI - Intracranial metastasis of sweat gland carcinoma. Case report. PMID- 4288761 TI - Hypophosphatasia: genetic and dental studies. PMID- 4288762 TI - Factors affecting sodium reabsorption by the proximal tubule as determined during blockade of distal sodium reabsorption. PMID- 4288763 TI - The antigens of vesicular stomatitis virus. II. The presence of two low molecular weight immunogens in virus suspensions. PMID- 4288764 TI - Effect of Merthiolate on agar gel diffusion precipitin reactions with foot-and mouth disease virus. PMID- 4288765 TI - Generalized type 5 adenovirus infection associated with the pertussis syndrome. PMID- 4288766 TI - Infantile myoclonic seizures: an evaluation of ACTH and corticosteroid therapy. PMID- 4288767 TI - Paget's disease of the nipple. PMID- 4288768 TI - Primary carcinoma of the liver in infancy and childhood: report of 21 cases, with resection in 6 cases. PMID- 4288769 TI - [Hormone treatment of neuritis of the facial nerve]. PMID- 4288770 TI - Localization of tissue sodium and potassium compartments in rabbit renal cortex. PMID- 4288771 TI - Indirect action of angiotensin infusion to inhibit renal tubular sodium reabsorption in dogs. PMID- 4288772 TI - [Lymphographic studies on the cervical lymphatic system]. PMID- 4288774 TI - Relative efficiency of three tissue culture systems for the primary isolation of viruses from feces. PMID- 4288773 TI - [Influence of the glucose load and of various hormones on the dynamics of nonesterified fatty acids in essential obesity]. PMID- 4288775 TI - Association of adenoviruses with other than respiratory illness. PMID- 4288776 TI - 17-hydroxylation deficiency in man. PMID- 4288777 TI - Persistance of adult Trichinella spiralis in pertussis-treated mice. PMID- 4288778 TI - An evaluation of the B-V (continuous-flow) and B-IV (density gradient) rotors by use of live polio virus. PMID- 4288779 TI - Use of zonal centrifuge to separate components of ribosomal RNA. PMID- 4288780 TI - Rhinovirus infections in an industrial population. I. The occurrence of illness. PMID- 4288781 TI - [On a case of nasal septum tumor with cylindromatous morphology]. PMID- 4288782 TI - The enzymatic synthesis of a copolymer of 6-methyl deoxyadenylate and deoxythymidylate. PMID- 4288783 TI - The DPNH-binding capacity of various dehydrogenases. PMID- 4288784 TI - Phenobarbital-induced synthesis of the oxidative demethylating enzymes of rat liver microsomes. PMID- 4288785 TI - DPNH oscillations in a cell-free extract of S. carlsbergensis. PMID- 4288786 TI - On the regulatory properties of deoxycytidylate aminohydrolase. PMID- 4288787 TI - A hydrophobic region at the active site of yeast alcohol dehydrogenase. PMID- 4288788 TI - Inhibition of thymidine kinase activity in liver and hepatomas by TTP and d-CTP. PMID- 4288789 TI - Some products of the degradation of blood group substances by alkaline borohydride. PMID- 4288790 TI - Some observations on the elution of progesterone from silica gel. PMID- 4288791 TI - Inhibition of ribosephosphate pyrophosphokinase activity by decoinine, an adenine nucleoside. PMID- 4288792 TI - Transfer of H from succinate to DPN catalyzed by the Slater-Keilin-Hartree preparation. PMID- 4288793 TI - A protein factor required for phosphorylation coupled to electron flow between reduced coenzyme Q and cytochrome c in the electron transfer chain. PMID- 4288794 TI - Selective inhibition by deoxyglucosyl thymine of thymidine phosphorylases not catalyzing deoxyribosyl transfer. PMID- 4288795 TI - Cimulative hemagglutination by Mycoplasma pneumoniae and other agglutinins. AB - John, T. Jacob (University of Colorado School of Medicine, Denver), Marlene Stahl, and Vincent A. Fulginiti. Cumulative hemagglutination by Mycoplasma pneumoniae and other agglutinins. J. Bacteriol. 92:1002-1004. 1966.-The phenomenon of cumulative hemagglutination, or hemagglutination by two agglutinins, each in subagglutinating concentration, was demonstrated by use of four different systems, namely, horse serum and Mycoplasma pneumoniae, horse serum and measles antigen, M. pneumoniae and measles antigen, and parainfluenza 2 virus and M. pneumoniae. Cumulative hemagglutination appears to be the mechanism by which a horse-serum diluent causes high hemagglutination titers of M. pneumoniae, since both contain hemagglutinins against vervet erythrocytes. It was also shown that antibodies against either one of the two antigens may cause inhibition of such hemagglutination. PMID- 4288796 TI - Quantitative aspects of inhibition of virus replication by interferon in chick embryo cell cultures. AB - Hallum, J. V. (University of Pittsburgh, Pittsburgh, Pa.), and J. S. Youngner. Quantitative aspects of inhibition of virus replication by interferon in chick embryo cell cultures. J. Bacteriol. 92:1047-1050. 1966.-The effect of interferon on single cycles of replication of vesicular stomatitis virus and Mahoney poliovirus ribonucleic acid was studied in chick embryo cell cultures. The results showed that the titer of a given interferon preparation was independent of the input multiplicity of the challenge virus. In addition, the increase in virus yield with increasing virus challenge was a function of the number of infected cells, each of which yielded progeny at a level determined by the concentration of interferon to which the cells were exposed. These findings are not compatible with the concept that increases in the size of the virus challenge reverse or overcome protection of cells by interferon. PMID- 4288797 TI - Effect of avian myeloblastosis virus in the Japanese quail. AB - Moscovici, Carlo (University of Colorado Medical Center, Denver), and E. H. Macintyre. Effect of avian myeloblastosis virus in the Japanese quail. J. Bacteriol. 92:1141-1149. 1966.-Avian myeloblastosis virus (AMV) induced a spectrum of neoplasms in Japanese quail (Coturnix coturnix japonica) which was similar to that observed in the chicken, with one exception: the total absence of acute myeloblastic leukemia in quail. Studies in vivo as well as in vitro suggested that the cause for this difference may be ascribed to the heterogeneity of AMV and to the genetic makeup of the quail cell. PMID- 4288798 TI - Control of dimorphism in Mucor rouxii. AB - Haidle, C. W. (The University of Texas, Austin), and R. Storck. Control of dimorphism in Mucor rouxii. J. Bacteriol. 92:1236-1244. 1966.-Yeastlike cells of Mucor rouxii NRRL 1894 were converted to filaments in a medium containing glucose, mineral salts, casein hydrolysate, nicotinic acid, and thiamine when the gas phase was changed from CO(2)-N(2) or N(2) alone to air. Germ tubes began to appear 3 to 4 hr after exposure to air. Ribonucleic acid (RNA) precursors were incorporated into RNA in a discontinuous fashion during this conversion, but the incorporation was continuous during the anaerobic growth of yeastlike cells and during the aerobic germination of sporangiospores. The incorporation of labeled amino acids during the conversion was exponential. Labeling of ribosomal RNA occurred as shortly as 5 min after replacement of CO(2)-N(2) with air. However, P(32)-labeled RNA isolated 20 min after exposure to air had a guanine plus cytosine (GC) content of 41% (mole%) as compared with the 47% found for labeled and unlabeled RNA isolated at other stages of the life cycle of this organism or later during the conversion. In addition, the overall base composition of this 20 min pulse-labeled RNA resembled that of deoxyribonucleic acid (GC = 39%), suggesting that a significant proportion of this RNA is of the messenger type. Furthermore, the synthesis of cytochrome oxidase was induced upon exposure of yeastlike cells to air. Cyanide, acriflavine, and cycloheximide, which inhibited the action or synthesis of cytochrome oxidase, also inhibited the yeast to filament transition. PMID- 4288799 TI - Rapid disruption of intact yeasts by synthetic zeolite. PMID- 4288800 TI - Neutralization of endotoxin toxicity in chick embryos by antibiotics. AB - Rifkind, David (University of Colorado Medical Center, Denver), and John D. Palmer. Neutralization of endotoxin toxicity in chick embryos by antibiotics. J. Bacteriol. 92:815-819. 1966.-Three cationic cyclic polypeptide antibiotics, polymyxin B sulfate colistin sulfate, and tyrocidine hydrochloride, were shown to neutralize endotoxin lethality in chick embryos. The neutralizing potency of these antibiotics was approximately equivalent, 0.06 to 0.11 mumole of antibiotic per mug of endotoxin. Methane sulfonation of colistin resulted in a 13-fold decrease in endotoxin-neutralizing potency. Other cationic cyclic polypeptide antibiotics were inactive, as well all other classes of antibiotics tested, including the neutral cyclic polypeptides. Several nonantibiotic polycationic proteins and polymers tested were also inactive. It is suggested that certain cationic cyclic polypeptide antibiotics neutralize by combining directly with the toxic moiety of the endotoxin molecule. Possibly this combination involves the cationic groups of the antibiotics and the polyphosphate groups of the phospholipid component of endotoxin. PMID- 4288801 TI - Characteristics of the photoreactivation of pseudorabies virus. AB - Pfefferkorn, E. R. (Harvard Medical School, Boston, Mass.), Boyce W. Burge, and Helen M. Coady. Characteristics of the photoreactivation of pseudorabies virus. J. Bacteriol. 92:856-861. 1966.-Pseudorabies virus, killed with ultraviolet light and then allowed to adsorb to chick embryo tissue culture cells, can be photoreactivated by light of longer wavelengths. The photoreactivable sector is approximately 0.5. Herpes simplex virus is equally photoreactivable. Photoreactivability is negligible during the first 20 min after adsorption and then rises to a maximum by 100 min. After this maximum is reached, photoreactivability decreases with increasing rate as the temperature of incubation is raised. Inhibition of protein synthesis immediately after absorption prevents the establishment of the photoreactivable state. PMID- 4288802 TI - Periodate inhibition of transformation and competence development in Haemophilus influenzae. AB - Ranhand, Jon M. (University of Cincinnati, Cincinnati, Ohio), and Herman C. Lichstein. Periodate inhibition of transformation and competence development in Haemophilus influenzae. J. Bacteriol. 92:956-959. 1966.-Periodate treatment of competent cells reduced the frequency of transformation to streptomycin resistance about 90% while reducing cell viability about 30% or less. Moreover, when periodate was added to cells early in the competence-development phase, these, too, were unable to develop maximal competence. Periodate inhibition was dependent on time and concentration as well as on the composition of the suspending menstruum. Periodate had no effect on transforming deoxyribonucleic acid (DNA), nor did it prevent transformation when added to competent cells which had already reacted with DNA. Furthermore, the progeny from cells inactivated 90% could be made fully competent, showing that the inhibition was not genetic. It was concluded that the periodate-sensitive substrate may involve the DNA binding site(s). PMID- 4288803 TI - Activity of mitomycin C, other antibiotics, and serum against lysogenic bacteria. AB - Muschel, Louis H. (University of Minnesota, Minneapolis), and Karen Schmoker. Activity of mitomycin C, other antibiotics, and serum against lysogenic bacteria. J. Bacteriol. 92:967-971. 1966.-Lysogenic bacteria were found to be more sensitive to the bactericidal action of mitomycin C or streptonigrin than the corresponding sensitive or indicator strains. This result may be attributed to the induction of phage production in lysogenic cells by these antibiotics. Lysogenic and sensitive bacteria were, however, equally sensitive to chloramphenicol, streptomycin, and polymyxin B. In contrast to their greater sensitivity to certain phage-inducing antibiotics, the lysogenic state resulted in greater resistance to the bactericidal reaction of serum mediated by the complement system. In general, therefore, the lysogenic state may result in either decreased or increased sensitivity to various antimicrobial agents. PMID- 4288804 TI - Mutants of simian virus 40 differing in plaque size, oncogenicity, and heat sensitivity. AB - Takemoto, K. K. (National Institute of Allergy and Infectious Diseases, Bethesda, Md.), R. L. Kirschstein, and K. Habel. Mutants of simian virus 40 differing in plaque size, oncogenicity, and heat sensitivity. J. Bacteriol. 92:990-994. 1966. Three mutants of simian virus 40 were isolated on the basis of the type of plaques produced in primary cultures of African green monkey kidney cells and designated as L (large), S (small), and M (minute) strains. Significant differences in oncogenicity for hamsters were observed, with the 50% oncogenic dose being 10(4.5) for the L, 10(5.2) for the S, and 10(5.8) for the M strains. All three strains were capable of transforming human diploid cells (W138 strain). At temperatures up to 41 C, the S and M mutants were capable of multiplying to titers almost equivalent to those obtained at 37 C. In contrast, infectious virus was not produced when cells were infected with the L mutant and were incubated at temperatures above 39 C, although complement-fixing viral and tumor antigens were formed. The temperature-sensitive phase of replication of the L strain was shown to be a late stage in viral maturation or assembly. PMID- 4288805 TI - Pathophysiology of arteriovenous shunts in the extremities. PMID- 4288806 TI - Enzyme histochemistry of adenoid cystic carcinoma of minor salivary glands. PMID- 4288807 TI - Granular cell myoblastoma of the tongue: report of case. PMID- 4288808 TI - [Effect of fluorite on the respiratory tract of rats]. PMID- 4288809 TI - [Effect of carbon disulfide on the cytochrome oxidase activity in rats]. PMID- 4288810 TI - [Pathogenesis, symptoms, first aid and treatment of acute poisoning by hydrogen cyanide and acrylonitrile]. PMID- 4288811 TI - [A malignant synovioma]. PMID- 4288812 TI - [Immunobiologic properties of the Asia-1 type strain of the foot-and-mouth disease virus]. PMID- 4288813 TI - [Growing of foot-and-mouth disease virus in tissue culture]. PMID- 4288814 TI - [Changes in Clostridium perfringens type B caused by ultraviolet rays]. PMID- 4288815 TI - [Susceptibility of swine to fowlpox virus]. PMID- 4288816 TI - [Simultaneous vaccination of chickens against laryngotracheitis and fowlpox]. PMID- 4288817 TI - [Experimental foot-and mouth disease in deer]. PMID- 4288818 TI - A study of the risk of mortality of varicella in patients with bronchial asthma or other allergic disease receiving corticosteroid therapy. PMID- 4288820 TI - An unusual oral manifestation in a case of acute myeloid leukaemia. PMID- 4288819 TI - Early changes in enzyme activity during the development of and recovery from vitamin D deficiency in the rat. PMID- 4288821 TI - Using x-rays to establish the correct age of children. Value of this procedure with Israel's immigrant youngsters. PMID- 4288822 TI - Presenting symptoms of neuroblastomas and Wilms' tumors. PMID- 4288823 TI - Surgical lengthening of the external nose to correct congenital or traumatic arrest of nasal growth (an operation of value in treating nasal deformities of cleft lip and palate). PMID- 4288824 TI - [On the nature of the latent damaged state in irradiated trypsin. Study by the ESR method]. PMID- 4288825 TI - [Pleomorphic adenoma]. PMID- 4288826 TI - Mice and monkeys as assay animals for Clostridium perfringens food poisoning. AB - Spores and vegetative cells of Clostridium perfringens, in combination with meat or starch paste, sterile culture filtrates, lecithinase, and phosphorylcholine, were administered to mice and rhesus monkeys in an attempt both to evaluate the animals as test agents and, if possible, to elucidate the active factors producing food-poisoning symptoms caused by this organsim. Some of the preparations were administered to the monkeys by stomach tube; others, in gelatin capsules which were treated with formaldehyde so that the release of their contents was delayed and presumably reached the intestines of the animals. Any changes in intestinal passage times and in consistency of stools of the animals were observed, and the counts of C. perfringens in the feces of the monkeys previous and subsequent to treatment were recorded. The results obtained were inconclusive. Diarrhea occurred only relatively infrequently in both species, regardless of the substance fed or the mode of administration. The changes in intestinal passage times were not great, although in the monkeys there appeared to be a slight trend toward reduction as the magnitude of the bacterial load increased. Phosphorylcholine appeared to have little, if any, effect in reducing intestinal passage time of mice or monkeys. No procedures explored in these experiments could be said to be satisfactory as a means of animal assay for food poisoning strains of C. perfringens since typical symptoms did not appear with regularity. PMID- 4288827 TI - Antibody response of guinea pigs to trivalent parainfluenza virus vaccine prepared from embryonated eggs. AB - A trivalent parainfluenza virus vaccine has been tested in guinea pigs. The parainfluenza 2 virus vaccine component was superior in the magnitude of antibody titers, and in the ability to convert animals serologically after two doses of an undiluted or a 10-fold diluted vaccine. The parainfluenza 1 virus vaccine gave a higher percentage of conversion than parainfluenza 3 virus vaccine after administration of two doses of either undiluted or 10-fold diluted vaccine. PMID- 4288828 TI - Antagonistic effect on Clostridium botulinum type E by organisms resembling it. AB - A bacteriocin-like substance, active against strains of Clostridium botulinum type E, is produced by certain nontoxic organisms whose biochemical properties and morphological characteristics are similar to type E. The substance, for which the name "boticin E" is proposed, is bacteriolytic for vegetative cells and bacteriostatic for spores of type E. Its spectrum of activity is somewhat strain specific. Of the clostridial species tested, only C. botulinum type E and, to a lesser extent, C. perfringens and C. acetobutylicum, but not C. botulinum types A, B, or F, are sensitive. Irreversibly resistant variants originating from both vegetative cells and spores of certain strains were obtained. The active substance is heat-stable and dialyzable, and is not inactivated by chloroform but is digested by trypsin. Ethyl alcohol and acetone precipitates are fully active, whereas trichloroacetic acid precipitates are only partially active. Other nontoxic organisms producing similar antagonistic substances are discussed. PMID- 4288829 TI - Technique for volume production of mouse ascites fluid containing Bordetella pertussis antibody. PMID- 4288830 TI - Non-fatal mouse cytomegalovirus hepatitis. Combined morphologic, virologic and immunologic observations. PMID- 4288831 TI - Acid phosphatase and lysosome activity in diphtheritic neuropathy and Wallerian degeneration. PMID- 4288833 TI - [Titration of antibodies against B. pertusis and B. parapertussis from blood eluates taken on paper rondels]. PMID- 4288832 TI - [Determination of the lecithinase activity of thermoresistant strains of Clostridium perfringens]. PMID- 4288834 TI - The population-dependent requirement by cultured mammalian cells for metabolites which they can synthesize. II. Glutamic acid and glutamine; aspartic acid and asparagine. PMID- 4288835 TI - [On peptide syntheses, 37. 4. Angiotensin analogs. Synthesis of D-asp-1-, glu-1-, glu(NH2)-1-and pyrogl-1-val-5-angiotensin II]. PMID- 4288836 TI - "Communalities" in the ossification timing of the growing foot. PMID- 4288837 TI - Programming of poliovirus inhibition of deoxyribonucleic acid synthesis in HeLa cells. AB - Ackermann, W. W. (The University of Michigan, Ann Arbor), and D. Wahl. Programming of poliovirus inhibition of deoxyribonucleic acid synthesis in HeLa cells. J. Bacteriol. 92:1051-1054. 1966.-Deletion of arginine from a culture medium reduced the rate of deoxyribonucleic acid (DNA) synthesis in uninfected HeLa cells. The normal rate was promptly restored by addition of arginine. Deletion of arginine also prevented poliovirus from inhibiting DNA synthesis in HeLa cells. However, the inhibitory potential of the infection and the capacity of the host cell for stimulation with regard to DNA synthesis were both retained in arginine-depleted cells which were infected. Upon addition of arginine late in the infection, DNA synthesis was first stimulated and then inhibited. PMID- 4288838 TI - Resolution of the components in the microsomal fraction of liver in the B-IV zonal centrifuge. PMID- 4288839 TI - [Morphological characteristics of monkey tumors induced with the Rous virus]. PMID- 4288840 TI - Some aspects of urea and pyrimidine metabolism during development. PMID- 4288841 TI - Central regulation of enzyme activity and synthesis in embryonal and adult mammalian tissues. PMID- 4288842 TI - Factors influencing the metabolism of brown adipose tissue in newborn mammals. PMID- 4288843 TI - Neurohumoral mediation of active reflex vasodilatation. PMID- 4288844 TI - Overnutrition on resistance of dogs to distemper virus. PMID- 4288845 TI - [Lymphography using iodine 131 in the surveillance and treatment of Hodgkin's disease. (Preliminary note apropos of 2 cases)]. PMID- 4288846 TI - [Congenital pseudohermaphroditism caused by a maternal virilizing tumor]. PMID- 4288847 TI - Colour, magnetic resonance and symmetry of the cupric site in blue protein. PMID- 4288848 TI - Triglyceride accumulation in liver. PMID- 4288849 TI - Small-plaque and large-plaque variants of Papova virus SV-40. PMID- 4288850 TI - Extragonadal estrogen production. PMID- 4288851 TI - The rat adenohypophysis during increased corticotrophin production. A histologica and autoradiographic study using labelled nucleic acid precursors after adrenalectomy, after protracted stress and after adrenalectomy followed by cortisone administration. PMID- 4288852 TI - Appearance of enterovirus in the Takatsuki district in Osaka after poliovirus vaccination. 1-I. Enterovirus isolation from the feces of normal and outpatient children. 1-II. Aseptic meningitis occurring in the summer of 1964. PMID- 4288853 TI - Appearance of enterovirus in the Takatsumi district in Osaka after poliovirus vaccination. 2. Neutralizing antibodies for ECHO-4, ECHO-6 and various types of poliovirus in the inhabitants. PMID- 4288854 TI - [Studies of the pituitary and adrenocortical functions in children with plasma free 11-OHCS as an indicator. II. Pituitary function test using synthesized lysine-8-vasopressin]. PMID- 4288855 TI - [Studies of the pituitary and adrenocortical functions in children with plasma free 11-OHCS as an indicator. 3. Its values and a loading test with ACTH-Z in various diseases]. PMID- 4288856 TI - Jugular foramen and early roentgen diagnosis of glomus jugulare tumor. PMID- 4288857 TI - New and simple techniques for demonstration of the jugular foramen. PMID- 4288858 TI - [Morphological study of glycogen particles observed in the minute structures of human brain tumors and normal mouse brain]. PMID- 4288859 TI - [Clinical study on posttraumatic sequelae of the brain, with special reference to the analysis of cases treated in the Department of Surgery]. PMID- 4288860 TI - Intraduct papilloma of the breast. PMID- 4288861 TI - Characterization of a vascular permeability factor of renal origin. PMID- 4288862 TI - Interference with feedback inhibition of adrenocorticotropin release by protein binding of corticosterone. PMID- 4288863 TI - Observations on the production of hydrogen ions during mobilization of fatty acids from adipose tissue. PMID- 4288864 TI - Isolation of a variant strain of foot-and-mouth disease virus (type O) during passage in partly immunized cattle. PMID- 4288865 TI - The infectivity assay of foot-and-mouth disease virus in pigs. PMID- 4288866 TI - Acquisition of Staphylococcus aureus by patients undergoing cytotoxic therapy in an ultra-clean isolation unit. PMID- 4288867 TI - In vivo replacement of the helper virus in Bryan's strain of Rous sarcoma virus by AMV and RPL12 viruses. PMID- 4288868 TI - Fluorescent antibody studies of viruses of the avian leukosis complex. PMID- 4288869 TI - Biological studies on a leukemia virus extracted from C3H plasma cell tumor 70429. PMID- 4288870 TI - The classification of malignant growths of the chorion. PMID- 4288871 TI - The environment and problems in selection for disease resistance in the fowl. PMID- 4288872 TI - Hypoglycemia in primary carcinoma of the liver. Report of a case. PMID- 4288873 TI - Performance of papillary muscles isolated from cats in postoligemic shock. PMID- 4288874 TI - Effect of cortisone on plasma iron concentration of normal and endotoxin-poisoned mice. PMID- 4288875 TI - Effect of condensed phosphates on calcification of chick embryo femurs in tissue culture. PMID- 4288876 TI - Actinomycin D effect on lag in vitamin D-mediated calcium absorption in the chick. PMID- 4288877 TI - ACTH secretion after pituitary stalk section in the dog. PMID- 4288879 TI - Hamartoma (leiomyomatous type) of the kidney. PMID- 4288878 TI - Coxsackie group B virus infection and acute diarrhoea occurring among children in Costa Rica. PMID- 4288880 TI - Lymphangiomyoma, a benign lesion of chyliferous lymphatics synonymous with lymphangiopericytoma. PMID- 4288881 TI - Ultrastructure of nasopharyngeal angiofibromas. PMID- 4288882 TI - Tryptophan metabolites in hypoglycemia associated with neoplasia. PMID- 4288883 TI - [ACTH-tropic action of a mixture of phospholipids from the bovine hypothelamus. Research in rats pretreated with dexamethasone]. PMID- 4288884 TI - [The process of maturation of the proximal epiphyses of both bones of the forearm in the female]. PMID- 4288885 TI - The significance of endocrine activity in hypophysectomized diabetics. PMID- 4288886 TI - Studies on the mechanims of oxidative phosphorylation. IX. Effect of cytochrome c on energy-linked processes. PMID- 4288887 TI - Wilms' tumor: factors influencing long-term survival. PMID- 4288889 TI - Age assessment in field surveys of children of the tropics. PMID- 4288888 TI - Cortisol production rate. V. Congenital virilizing adrenal hyperplasia. PMID- 4288890 TI - Sacrococcygeal teratoma in a newborn girl with massive intra-abdominal extension: combined abdominosacral approach. PMID- 4288891 TI - [Hypoglycemic pancreatopathy. 3. Therapy with statistical evaluation]. PMID- 4288892 TI - The tautomerism of quinones and the question of quinone methide intermediates in oxidative phosphorylation. PMID- 4288893 TI - Dihydroorotate dehydrogenase. 3. Interactions with substrates, inhibitors, artificial electron acceptors, and cytochrome c. PMID- 4288894 TI - The sialic acids. X. Purification and properties of cytidine 5'-monophosphosialic acid synthetase. PMID- 4288895 TI - Mechanism of the salicylate hydroxylase reaction. PMID- 4288896 TI - Phosphoenolpyruvate carboxytransphosphorylase. II. Crystallization and properties. PMID- 4288897 TI - The equilibria of reactions catalyzed by carboxytransphosphorylase, carboxykinase, and pyruvate carboxylase and the synthesis of phosphoendolpyruvate. PMID- 4288898 TI - [Complications caused by methiodal. Limitations and contraindications of the technic]. PMID- 4288899 TI - Some quantitative observations upon the oxidation of substrates of the tricarboxylic acid cycle in injured neurons. PMID- 4288900 TI - Observations on the ganglion-stimulating action of angiotensin and bradykinin. PMID- 4288901 TI - The protective effect of aldrin against the toxicity of organophosphate anticholinesterases. PMID- 4288902 TI - Prevention and remission by adrenocortical steroids of nicotinamide deficiency disorders and of 6-aminonicotinamide toxicity in rats and dogs. PMID- 4288903 TI - Biological activity of medrogestone: a new orally active progestin. PMID- 4288904 TI - Clostridium perfringens; septicemia following perforation of a duodenal ulcer. PMID- 4288905 TI - [Fumagillin in the treatment of infantile amebiasis]. PMID- 4288906 TI - [Histochemical studies on the protein level in the diet on the activity of some phosphatase in the small intestine and liver of rats. Preliminary report]. PMID- 4288907 TI - [Differential diagnosis of Newcastle disease (pseudoplague) and classical fowl plague]. PMID- 4288908 TI - [Fine structure of variola viruses in hens and pigeons]. PMID- 4288909 TI - [Effect of the duckling hepatitis virus ON THE CELLS OF TISSUE CULTURES OF CHICKEN KIDNEYS AND DUCK EMBRYOS]. PMID- 4288910 TI - [Efficiency of polymyxin M in pullorum disease in chickens]. PMID- 4288911 TI - The Rauscher virus: a mixture of the Friend virus and of the mouse leukemia virus (Gross)? PMID- 4288912 TI - The determination of molybdenum in natural waters, silicates and biological materials. PMID- 4288913 TI - [Respiratory virus antibodies in human sera from different regions of the world]. PMID- 4288915 TI - A practitioner's investigation of a possible outbreak of Blackleg. PMID- 4288914 TI - Hypernephroma and amyloidosis. PMID- 4288916 TI - Hormonal control of melanin pigmentation in scrotal skin of the rat. PMID- 4288917 TI - Anaerobic bacteria in routine urine culture. AB - One hundred and fifty-eight anaerobic organisms from 147 patients were isolated from 15,250 consecutive clean mid-stream or catheter urine specimens. The pathogenicity of the anaerobic genera commonly isolated from urine is reviewed and discussed. Failure to establish anaerobic isolates as pathogens and a paucity of reported cases proving anaerobic bacteria as significant causes of urinary tract infection permitted discontinuation of anaerobic culture as part of the routine screening procedure for investigation of urinary tract infections. PMID- 4288918 TI - Light-induced alterations in melanoma-related free radicals, and the consequences on respiration and growth. PMID- 4288919 TI - Measurement of renin and substrate concentrations in human serum. PMID- 4288920 TI - The end of the beginning. PMID- 4288921 TI - Nursing with medicine. PMID- 4288922 TI - H reflex study in upper motoneuron diseases. PMID- 4288923 TI - Measurement of the pain threshold determined by electrical stimulation and its clinical application. II. Clinical application in neurological and neurosurgical patients. PMID- 4288924 TI - Cytomegalic inclusion disease of infancy. PMID- 4288925 TI - [Participation of the thyroid gland in adaptation processes of liver glucose-6 phosphatase in rats]. PMID- 4288926 TI - Arteriographic demonstration of pancreatic tumor in the Zollinger-Ellison syndrome. PMID- 4288927 TI - Chemodectoma of the vagus nerve. PMID- 4288928 TI - The in vivo effect of quartz and carborundum dusts on the activity of cytochrome C oxidase and the DNA content of rat lung tissue. PMID- 4288929 TI - [Hyperbaric oxygenation]. PMID- 4288930 TI - Selective inhibition of poliovirus growth by d-Penicillamine in vitro. PMID- 4288931 TI - Physiological characterization of heat-defective (temperature-sensitive) poliovirus mutants: preliminary classification. PMID- 4288932 TI - Enhancement of the thymidine kinase activity of human embryonic kidney cells and newborn hamster kidney cells by infection with human adenovirus types 5 and 12. PMID- 4288933 TI - Different transplantation antigens in BHK21 cells transformed by four strains of polyoma virus. PMID- 4288934 TI - Induction of specific antitumor immunity in hamsters with hydroxylamine inactivated SV40 virus. PMID- 4288935 TI - Fetal ascites and cytomegalic inclusion disease. PMID- 4288936 TI - Reconstitution of cytochrome c oxidase from an apo-enzyme and Cu (I). PMID- 4288937 TI - Electron spin resonance spectra of spinach ferredoxin. PMID- 4288938 TI - Phosphodiesterases active against glucose cyclic phosphates. PMID- 4288939 TI - Inhibition of cyclic nucleotide phosphodiesterase by adenosine 5'triphosphate and inorganic pyrophosphate. PMID- 4288940 TI - Adrenal failure complicating status asthmaticus in steroid-treated patients. PMID- 4288941 TI - Glyconeogenesis of old diabetics. PMID- 4288942 TI - Dietary modifications of cold-induced metabolic effects. PMID- 4288943 TI - [Tracheobronchial resection-anastomosis for neoplasm]. PMID- 4288944 TI - [Dynamics of the formation of different components of the toxin of Cl. perfringens type A]. PMID- 4288945 TI - [Factors causing the restoration of toxic properties in centrifugates of Cl. perfringens cultures which lost their toxicity]. PMID- 4288946 TI - [Parapertussis bacilli isolated in the pertussis foci and their properties]. PMID- 4288947 TI - [Bacterial flora in pneumonia and acute catarrh of adenoviral etiology]. PMID- 4288948 TI - Iodinated oil emulsion for lymphography. PMID- 4288949 TI - [Fatal hydrocyanic acid poisoning by eating sweet cassava (Manihot aipi). Report on 2 cases]. PMID- 4288950 TI - [Enzymes and bladder calculi]. PMID- 4288951 TI - Experience in the treatment of Crohn's disease of the large intestine. PMID- 4288952 TI - Effect of normal and atheromatous aortic tissue on platelet aggregation in vitro. AB - An investigation was made into the platelet-aggregating ability of human aortic tissue. It was found that potent aggregating substances are present in the vascular wall but that the degree and character of platelet aggregation produced was dependent on the method employed in the preparation of the tissue for study. The supernatants of aortic tissue homogenates were found to produce potent irreversible platelet aggregation that occurred after a latent period of one to two minutes. The activity was heat labile, destroyed by collagenase, sedimented by ultracentrifugation, and was considered to be identical or similar to collagen. An extract obtained by boiling aortic tissue with saline was found to cause less powerful reversible platelet aggregation that occurred within 15 to 30 seconds' contact with platelets; the activity was not affected by heating, incubation with collagenase, or ultracentrifugation, and was considered to be due to adenosine diphosphate. Atheromatous aortic tissue when extracted by either method was found to contain less than one half of the potency of normal tissue in causing platelet aggregation. PMID- 4288954 TI - [Electrophysiological examination methods in injuries and functional disorders of the peripheral nervous system]. PMID- 4288953 TI - Preparation of phosphatidyl inositol from baker's yeast. AB - Phosphatidyl inositol and a cardiolipin-like phospholipid survive the autolysis which is induced in yeast by treating it with toluene, whereas other phospholipids are extensively degraded. Lipid from autolyzed yeast was suspended in isopropanol to extract lecithin and neutral lipid. The insoluble phosphatidyl inositol and cardiolipin were then separated by chromatography on silicic acid. PMID- 4288955 TI - Malignant hepatoma: repeated resection of metastases with survival for 15 years. PMID- 4288956 TI - Pleomorphic adenoma of the palate. Report of a case. PMID- 4288957 TI - Mucoepidermoid tumor of the maxilla. Report of a case. PMID- 4288958 TI - [Angiohistiocytoma]. PMID- 4288959 TI - [Industrial hygienic and toxicologic studies with hydrophobic amorphic silicic acids. I. Aerosil-R 972]. PMID- 4288960 TI - The vulnerability of the posterior interosseous nerve of the forearm. A case report and an anatomical study. PMID- 4288961 TI - Posterior interosseous nerve paralysis caused by a ganglion at the elbow. PMID- 4288962 TI - Non-traumatic progressive paralysis of the posterior interosseous nerve. PMID- 4288963 TI - The assay, extraction and storage of infective ribonucleic acid from foot and mouth disease virus. PMID- 4288964 TI - Silica gel as a preserving agent for the cellular slime mold Acrasis rosea. PMID- 4288965 TI - Malic dehydrogenase heterogeneity in malaria (Plasmodium lophurae and P. berghei). PMID- 4288966 TI - Autoradiographic studies of H3-thymidine uptake in Entamoeba histolytica in CLG medium. PMID- 4288967 TI - Histochemical studies on enzyme activities of gastric carcinoma. I. Hydrolytic enzymes. PMID- 4288968 TI - [Experimental poxvirus keratitis in immunized rabbits]. PMID- 4288969 TI - Purification of allergenic macromolecular compounds isolated from air-borne particles on thin-layer and preparative chromatography. PMID- 4288970 TI - Discrepancy of adrenal responses in diphenylhydantoin-treated rats. PMID- 4288971 TI - [Changes in vascular reactivity of the cat evoked by reserpine, guanethidine and alpha-methyldopa]. PMID- 4288972 TI - The cytomegalic inclusion cell. An elctron microscopic study. PMID- 4288973 TI - Electrodiagnosis of tarsal tunnel syndrome. PMID- 4288974 TI - (K+)-dependent acyl phosphatase as part of the (na+ + K+)-dependent ATPase of cell membranes. PMID- 4288975 TI - Oxalyl-coenzyme A synthetase from pea seeds. PMID- 4288976 TI - Inability of rat-liver mitochondria to oxidize betaine aldehyde. PMID- 4288977 TI - Cytochrome oxidase and its derivatives. V. The reaction of ferrous cytochrome c oxidase with oxygen and hydrogen peroxide in the presence of sodium dithionite. PMID- 4288978 TI - On cytochrome c oxidase. I. The extinction coefficients of cytochrome a and cytochrome a3. PMID- 4288979 TI - On cytochrome c oxidase. II. The ratio of cytochrome a to cytochrome a3. PMID- 4288980 TI - The effect of digitonin on the respiratory chain enzymes of a heart-muscle preparation. PMID- 4288981 TI - [Evaluation of treatment of tumors of the pituitary gland and its adjacent structures]. PMID- 4288982 TI - Kinetic studies on the mechanism of cytoplasmic L-alpha-glycerophosphate dehydrogenase of rabbit skeletal muscle. PMID- 4288983 TI - [Oxidation phosphorylation and respiration in liver mitochondria and solid hepatoma of mice suppressed by propylgallate]. PMID- 4288984 TI - [Pleiotropy of guanidine mutations of the poliomyelitis virus]. PMID- 4288985 TI - Pituitary-adrenal function in the absence of vasopressin. PMID- 4288986 TI - Sweating and glycogenolysis in the palmar eccrine sweat glands of the rhesus monkey. PMID- 4288987 TI - Virus-specific RNA in cells productively infected or transformed by polyoma virus. PMID- 4288988 TI - [Electron microscope examination of RNA from avian myeloblastosis virus]. PMID- 4288989 TI - The effects of adrenalectomy and splenectomy on Trypanosoma lewisi infection in white rats. PMID- 4288991 TI - Detection of ectromelia virus and ectromelia antibodies by immunofluorescence. PMID- 4288990 TI - Effect of caesarean-derivation, gnotobiote foster nursing and barrier maintenance of an inbred mouse colony on enzootic virus status. PMID- 4288992 TI - Cryosurgical treatment of juvenile laryngeal papillomatosis. PMID- 4288993 TI - The association of indirect inguinal hernia with congenital cytomegalic inclusion disease. PMID- 4288994 TI - Equine rhinopneumonitis virus as a cause of abortion in pregnant mares. PMID- 4288995 TI - Histological lesions and virus isolation in rhinopneumonitis infection. PMID- 4288996 TI - Virus infections of the human foetus. PMID- 4288997 TI - [Pressor activity in renal veins plasma in renal hypertension]. PMID- 4288998 TI - Lipogenesis in the hepatic tissue; lipogenesis and lipolysis in the adipose tissue of hyperglyceridemic and atherosclerotic patients. PMID- 4288999 TI - [Case of leucine-sensitive hypoglycemia treated by pancreatectomy]. PMID- 4289000 TI - [The value of dacryocystography for dacryocystorhinostomy (lipidol ultra-fluid as contrast medium in the lacrimal drainage system)]. PMID- 4289001 TI - Nature of anaemia in rheumatoid arthritis. VI. Metabolism of endogenous iron. PMID- 4289002 TI - Pathogenesis and management of abdominal wall hematomas. PMID- 4289003 TI - Fat metabolism in higher plants. 30. Enzymatic synthesis of ricinoleic acid by a microsomal preparation from developing Ricinus communis seeds. PMID- 4289004 TI - Structure of the neutral trisaccharide of the chondroitin 4-sulfate-protein linkage region. PMID- 4289005 TI - [Clinical study of 120 cases of chorioepithelioma and destructive hydatidiform mole--their characteristic difference]. PMID- 4289006 TI - [Advances in enzymology in urology]. PMID- 4289007 TI - An autopsy case of renal disease similar to lipoid nephrosis modified by steroid treatment. PMID- 4289008 TI - [Granular cell tumors of the oral cavity: apropos of 3 cases]. PMID- 4289009 TI - The influence of respiratory disease on the nasal carriage of staphylococci. PMID- 4289010 TI - Histological studies of the monkey neurovirulence of group B arboviruses. II. Selection of indicator centers. PMID- 4289011 TI - [A study on sorption purification of florimycin with ion-exchange resins]. PMID- 4289012 TI - [The riboflavin content of the organs of mice with transplanted tumors]. PMID- 4289013 TI - [A case of synovioma malignum in histological and clinical aspects]. PMID- 4289014 TI - Dual transfer of the posterior tibial and flexor digitorum longus tendons for drop foot. Report of thirty-one cases. PMID- 4289015 TI - Effect of age on the induction of glucose-6-phosphatase and fructose-1, 6 diphosphatase in rat liver. PMID- 4289016 TI - Changes in adrenocortical function during aging in cattle. PMID- 4289017 TI - Electron spin resonance technique for investigating reactions of free radicals with compounds of biological interest: nucleic acid constituents. PMID- 4289018 TI - Physico-chemical properties of silica in relation to its toxicity. PMID- 4289020 TI - [Cardiac insufficiency in infants with chorioretinitis and urinary cytomegalic inclusions]. PMID- 4289019 TI - [Squamous cell metaplasia in gastric carcinoma]. PMID- 4289021 TI - [New concepts in diagnosis and treatment of ulcerative colitis]. PMID- 4289022 TI - [Chemodectoma of the stomach (case report)]. PMID- 4289023 TI - [Angioarchitectonics of the stomach glomus tumor (case report)]. PMID- 4289024 TI - [New evidence for the inclusion of host antigens into the virus structure]. PMID- 4289025 TI - [Study of the virus-specific protein in destroyed cells of infected poliovirus RNA]. PMID- 4289026 TI - [Interference of Japanese encephalitis virus with certain cytopathogenic viruses in tissue cultures]. PMID- 4289027 TI - [Chicken myeloblastosis virus in a human cell culture]. PMID- 4289028 TI - [Suppression of the DNA activity in the RNA-dependent polymerase of cells infected with poliomyelitis virus]. PMID- 4289029 TI - Primary liver carcinoma in young men. PMID- 4289030 TI - Hemorrhage and pain from malignant hepatoma. PMID- 4289031 TI - Fructose 1,6-diphosphate aldolase of Candida utilis: purification and properties. PMID- 4289032 TI - Ubiquinone and menaquinone in bacteria: a comparative study of some bacterial respiratory systems. PMID- 4289033 TI - Hydroxylation of deoxycorticosterone by Bacillus cereus, strain T. PMID- 4289034 TI - Studies on the electron transfer system. LXVII. Polyacrylamide gel electrophoresis of the mitochondrial electron transfer complexes. PMID- 4289035 TI - Fructose diphosphatase from rabbit liver. V. Subunit structure of the purified enzyme. PMID- 4289036 TI - Purification and properties of fructose 1,6-diphosphatase from Polysphondylium pallidum. PMID- 4289037 TI - The specific fructose diphosphatase of Escherichia coli: properties and partial purification. PMID- 4289038 TI - Cytochrome c oxidase. 8. Lipid content. PMID- 4289040 TI - Clinical neuropathological conference. PMID- 4289039 TI - Ultrastructure of a human hepatocellular carcinoma and surrounding non-neoplastic liver. PMID- 4289041 TI - Influence of glucose uptake by adipose tissue on its lipolytic activity during action of certain hormones and in experimental diabetes. PMID- 4289042 TI - Effect of 6-methylthiouracil and thyroxin on deciduoma formation in ovariectomized rats. PMID- 4289043 TI - Effects of corticosteroids and ACTH on the hypophyseal-adrenocortical system. PMID- 4289044 TI - Characteristics of transplantable human embryonal cells transformed by simian virus 40. PMID- 4289045 TI - Experimental disciform keratitis. I. Immune response of the cornea to herpes simplex virus. PMID- 4289046 TI - Phospholipids in human young placenta. PMID- 4289047 TI - Purification and properties of whale pancreatic ribonucleases. PMID- 4289048 TI - Studies on cell walls of Mycobacteria. I. Chemical and biological properties of the cell walls and the mucopeptide of BCG. PMID- 4289049 TI - The presence of D-glucose 1,6-diphosphate hydrolyzing enzymes. PMID- 4289050 TI - Studies on the mechanism of oxidative phosphorylation. X. The effect of cytochrome C on energy-linked processes in submitochondrial particles. PMID- 4289051 TI - The isolation and characterization of malate-lactate transhydrogenase from Micrococcus lactilyticus. PMID- 4289052 TI - The purification and properties of pig liver geranyl pyrophosphate synthetase. PMID- 4289054 TI - Normotensive secondary hyperaldosteronism. PMID- 4289053 TI - The effect of insulin on enzyme adaptations to diets and hormones. PMID- 4289055 TI - [Allopathy--homeopathy]. PMID- 4289056 TI - [Isolation of vaccine poliovirus from sewage]. PMID- 4289057 TI - [Cytopathological aspects of some myxovirus and reovirus strains]. PMID- 4289058 TI - Intracystic carcinoma of the female breast. PMID- 4289059 TI - [Tryptophan pyrrolase activity in the liver and in some transplantable C3HA mouse hepatomas]. PMID- 4289061 TI - [Kaposi's varicelliform eruption. A case with detection of a virus]. PMID- 4289060 TI - [The use of phosphoprotein phosphatase for revealing phosphoproteins in cell organoid ultrastructures]. PMID- 4289063 TI - Counter-current distribution of poliovirus type 2 and 3. PMID- 4289062 TI - Enzymatic activities of Toxoplasma gondii. PMID- 4289064 TI - [On the appearance of glucose-6-phosphatase in the pancreas of the white rat during alloxan diabetes]. PMID- 4289065 TI - Effect of silica on protein biosynthesis by rat liver cell-free systems. PMID- 4289066 TI - Electron microscopic observations on RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens, and Japanese quail. PMID- 4289067 TI - Biological studies with RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens, and Japanese quail. PMID- 4289068 TI - Virus production in rat tumors induced by chicken sarcoma virus. PMID- 4289069 TI - Effects of trypan blue on hepatocarcinogenesis in rats given ethionine or N-2 fluorenylacetamide. PMID- 4289070 TI - Factors in the causation of spontaneous hepatomas in mice. PMID- 4289071 TI - Mechanisms for congenital transmission of avian leukosis virus. PMID- 4289072 TI - [Cylindromas of the oral cavity]. PMID- 4289073 TI - [Use of the Thorn test in patients with periodontopathies. Clinical statistical data]. PMID- 4289074 TI - Selective and reversible inhibition of proliferation and influence on metabolic functions in L cells by low cortisol concentrations. PMID- 4289075 TI - Ocular involvement in congenital cytomegalic inclusion disease. PMID- 4289076 TI - Antigenic analysis of tumors and sera from aimals inoculated with para-adenovirus populations. PMID- 4289077 TI - Heat production in adipose tissue. PMID- 4289078 TI - Three outbreaks of foodborne disease with dual etiology. PMID- 4289079 TI - Complement-fixing antibodies produced in guinea pigs immunized with purified N and H antigens of poliovirus. PMID- 4289080 TI - The etiology and clinical course of bullous myringitis. PMID- 4289081 TI - [Therapeutic trials in a case of orthostatic hypotension]. PMID- 4289082 TI - [Topochemical enzyme studies on the adrenal cortex of the guinea pig following administration of metopirone]. PMID- 4289083 TI - [Aging from the viewpoint of neurology]. PMID- 4289084 TI - The corticotherapy in experimental trichinellosis. PMID- 4289085 TI - [Behavior of Trichinella spiralis capsulae after ACTH treatment]. PMID- 4289086 TI - Production of polyoma virus haemagglutination inhibitors in mouse kidney epithelial monolayers. PMID- 4289087 TI - The etiology of respiratory tract infections in military personnel. 6. A critical evaluation of a study during the years 1960-1963. PMID- 4289088 TI - Diagnosis of asymptomatic meningococcal carriers by a selective medium. PMID- 4289089 TI - Antagonistic effect on melanocyte-stimulating hormone release of two neural tissue extracts. PMID- 4289090 TI - [Neomycin-resistant forms of colienteritis in children and their treatment]. PMID- 4289091 TI - [Cylindroma of the palate]. PMID- 4289092 TI - [On the significance of the 2,3-diphosphoglycerate cycle in erythrocytes: relationships between methemoglobin- and 2,6-dichlorphenolindophenol-reduction, glycolysis and 2,3,-diphosphoglycerate formation]. PMID- 4289093 TI - S-adenosylmethionine-synthesizing activity of normal and neoplastic mouse tissues. PMID- 4289094 TI - Activities of DNA nucleotidyltransferases and other enzymes in cell-free preparations from hepatomas of different growth rates. PMID- 4289095 TI - Studies on the pathogenesis of plasma cell tumors. II. The role of mast cells and pituitary glycoprotein hormones in the inhibition of plasma cell tumorigenesis. PMID- 4289096 TI - Large head and acute brain syndrome in a 17-year-old, mentally defective female; a clinical pathologic conference. PMID- 4289097 TI - [The use of corticosteroids and ACTH in the treatment of experimental acute pancreatitis]. PMID- 4289098 TI - [Effect of ACTH and cortisone on the course of experimental pancreonecrosis]. PMID- 4289099 TI - Experimental study on alimentary infection with poliovirus and local immunity of intestines. I. Immunofluorescent study on the sites of primary multiplication of poliovirus following alimentary infection in monkeys. PMID- 4289100 TI - [Interaction of chondromucoprotein and chondroitin sulfate A with polymyxin M]. PMID- 4289101 TI - [Changes in the activity of some enzymes participating in carbohydrate metabolism in tissue cultures infected by viruses and their infectious RNA]. PMID- 4289102 TI - [Effect of cortisone and hydrocortisone on the glucose-6-phosphatase activity of the liver in chick embryos]. PMID- 4289103 TI - [On the activity of neuraminic acid aldolase and neuraminidase in the cells of ascite and solid forms of hepatoma 22 in mice]. PMID- 4289104 TI - [Effect of NAD level in tumor and regenerating tissues on their sensitivity to sarcolysine]. PMID- 4289105 TI - [Long-term results of treatment of the so-called mixed tumors of the parotid salivary gland (according to the records of the P. A. Herzen State Oncological Institute for 1945-1962)]. PMID- 4289106 TI - [Adrenal cortex function in patients with malignant neoplasms of the kidneys]. PMID- 4289107 TI - Osteonecrosis and sarcoma following external irradiation of intracerebral tumors. PMID- 4289108 TI - The pressor response to noradrenaline and tyramine during angiotensin tachyphylaxis in the dog. PMID- 4289109 TI - The relationship between the vascular responses to the peptides angiotensin and pitressin. PMID- 4289110 TI - [Study of the immunity state in the potency test of pertussis vaccine by mouse intracerebral method]. PMID- 4289111 TI - Inheritance of susceptibility to Friend mouse leukemia virus. 3. Susceptibility of F1 and genotypes of F2 and backcross progeny. PMID- 4289112 TI - [Experimental resistance of polio virus type II to pyrimidine analogs S-7 and S 10)]. PMID- 4289113 TI - [Effect of ACTH and some adrenocortical hormones on convulsions induced by isonicotinic acid hydrazide]. PMID- 4289114 TI - Management of withdrawal from alcohol (including delirium tremens). PMID- 4289115 TI - Clostridium welchii infection in gastric surgery. PMID- 4289116 TI - Viruses isolated from children with infectious hepatitis. PMID- 4289117 TI - Primary carcinoma of the liver (hepatoma). Its diagnosis by selective celiac arteriography. PMID- 4289118 TI - [The plantar arch in the population of Ivory Coast]. PMID- 4289119 TI - Estimation of left ventricular volume by one-plane cineangiography. PMID- 4289120 TI - Estrogen replacement therapy at menopause. PMID- 4289121 TI - [An end to the bothers of the menopause]. PMID- 4289123 TI - In-patient care in a comprehensive community mental health center. PMID- 4289122 TI - Reaction of cobalt-chromium casting alloy with investment. PMID- 4289124 TI - Analysis of the Mellameter--a calibrated device for dispensing Mellaril concentrate. PMID- 4289125 TI - Sheltered boarding care: program coordination. PMID- 4289126 TI - "Support"--its meaning for psychiatric nurses. PMID- 4289127 TI - The role and the tasks of the Institute of Mental Health in Belgrade. PMID- 4289128 TI - Relationship between physical contact and verbal interaction between nurses and patients. PMID- 4289129 TI - Nurses--are they really wanted? PMID- 4289130 TI - Psychiatric drugs and trends: LSD. PMID- 4289131 TI - Geriatrics. PMID- 4289132 TI - Assessing the family's nursing needs. PMID- 4289133 TI - A new embedding material in frozen tissue techniques. PMID- 4289134 TI - Cystathioninuria. PMID- 4289135 TI - [Histomorphological description of mixed tumors of the palate. Histological contribution]. PMID- 4289136 TI - S to N acetyl migration in yeast glyceraldehyde-3-phosphate dehydrogenase. PMID- 4289137 TI - Initial myocardial succino-oxidase activity changes induced by intravenous infusion of Escherichia coli endotoxin in rabbit. PMID- 4289139 TI - Peroneal palsy due to hematoma in the common peroneal nerve sheath after distal torsional fractures and inversion ankle sprains. PMID- 4289138 TI - [Topochemical enzyme studies on the adrenal cortex of the guinea pig following termination of a long-term pretreatment with cortisone]. PMID- 4289140 TI - Cutaneous nephrogastric fistula: case report. PMID- 4289141 TI - Adenocarcinoma of the renal pelvis. PMID- 4289142 TI - Subtotal pancreatectomy in the management of severe persistant idiopathic hypoglycemia in children. PMID- 4289143 TI - Islet cell adenoma in childhood: report of a case. PMID- 4289144 TI - Mutations, chromosomal aberrations, and tumors in insects treated with oncogenic virus. AB - An increased incidence of lethal mutations, visible mutations, chromosomal losses, chromosomal nondisjunctions, and tumors resulted when drosophila were placed in medium containing Rous-sarcoma virus. In the group treated, a few mosaics of the eye and translocations appeared as well. There is a suggestion, from preliminary data, that the size of chromosomal puffs may be reduced by this RNA virus, but the difference is not significant. Tests for the persistence of virus in progeny have been negative so far. PMID- 4289145 TI - [Determination of biological activity in soil with enzyme methods]. PMID- 4289146 TI - A spectrophotometric method for the determination of microquantities of free inositol in biological material. PMID- 4289147 TI - The "Commando-operation". PMID- 4289148 TI - NADH-oxidizing activity of the labyrinthine fluids. PMID- 4289149 TI - Cryosurgery of the head and neck. PMID- 4289150 TI - Effects of pituitary and adrenal tissue slices and hormones on the pigmentation of MM2 (melanotic melanoma) cells in tissue culture. PMID- 4289151 TI - Binding of streptolysin S to red blood cell ghosts and ghost lipids. PMID- 4289152 TI - The use of an accelerated adsorption method in a quantal estimation of the infectivity of Herpesvirus hominis. PMID- 4289153 TI - Hepatic embryonic mixed tumour in an adult. PMID- 4289154 TI - Chemodectoma of the pineal region, with observations on the pineal body and chemoreceptor tissue. PMID- 4289155 TI - Tumours in young chickens bred for rapid body growth (broiler chickens): a study of 351 cases. PMID- 4289156 TI - The incidence of tumours in young chickens. PMID- 4289157 TI - Adrenocortical function in alcoholics. PMID- 4289158 TI - Thyroxin, satellite association and trisomy. PMID- 4289159 TI - Rapid ascites tumour production. PMID- 4289160 TI - Isolation of a tumour virus from a chicken submitted to a poultry diagnostic laboratory--Esh sarcoma virus. PMID- 4289161 TI - Glyoxylate reductase activity of lactate dehydrogenase. PMID- 4289162 TI - A comparison of electroencephalography and brain scan in supratentorial tumors. PMID- 4289163 TI - Studies on adenovirus pneumonia in infants and young children. PMID- 4289164 TI - [Electrophysiological and histological observations on the retrograde effects of nerve sectioning]. PMID- 4289165 TI - Tumor extension from the glomeruli to the tubuli in experimental kidney metastasis. PMID- 4289166 TI - Influence of dietary sodium on stimuli causing renin release. PMID- 4289167 TI - Role of catecholamine release in cardiovascular responses to angiotensin. PMID- 4289168 TI - Peripheral adrenergic basis for cardioaccelerator action of angiotensin. PMID- 4289169 TI - Anaesthesia for the surgical treatment of hyperinsulinism. Case reports. PMID- 4289170 TI - Tricholemmoma of the scalp. Case report. PMID- 4289171 TI - Histochemistry and fine structure of 4-nitroquinoline-N-oxide-induced nuclear inclusions. PMID- 4289172 TI - Studies on connective tissue tumors in the hamster produced by bovine papilloma virus. PMID- 4289173 TI - Lack of secretion of serum protein by transplanted rat hepatomas. PMID- 4289175 TI - [Endocrine diseases in islet cell tumors of the pancreas]. PMID- 4289174 TI - Antitumor activity of periodate-oxidation products of carbohydrates and their derivatives. PMID- 4289176 TI - The bacteriology of necrotizing jejunitis in Uganda. PMID- 4289177 TI - Histogenesis of malignant neoplasm induced by adenovirus type 12. PMID- 4289178 TI - Biochemical changes in tumor cells caused by antitumor agents. I. Effects of several antitumor agents on NAD content and NAD-glycohydrolase activity in Yoshida sarcoma cells and rat liver. PMID- 4289179 TI - Chromosomal alteration and the development of tumors. XII. Differentiation of karyotypes in mouse ascites hepatomas MH-134 and MH-129P maintained in different locations. PMID- 4289180 TI - [An elective polymyxin medium for the isolation and quantitative determination of enterococci in the feces and the environment]. PMID- 4289181 TI - Primary adenocarcinoma of renal pelvis (review of literature with first case report from India). PMID- 4289182 TI - Mucus producing adenocarcinoma of renal pelvis (report of a case and review of the literature). PMID- 4289183 TI - Hepatoblastoma: report of a case. PMID- 4289184 TI - Mechanism of synthesis of deoxyribonucleic acid in vivo. The heterogeneity of incorporation of 32-P into the deoxyribonucleotidyl units in Escherichia coli. PMID- 4289185 TI - Effect of hypophysectomy on pyridine nucleotide metabolism. The role of nicotinamide. PMID- 4289186 TI - Lipoamide dehydrogenase from human liver. PMID- 4289187 TI - Fructose diphosphatase from rabbit liver. 8. The involvement of tyrosine residues in the catalytic activity. PMID- 4289188 TI - The enzymic synthesis of chorismic and prephenic acids from 3-enolpyruvylshikimic acid 5-phosphate. PMID- 4289189 TI - An ultrastructural study of inter-specific cell fusion induced by inactivated Sendai virus. PMID- 4289190 TI - Three angiotensin tests in the investigation of renal hypertension: bioassay, infusion, renogram. PMID- 4289191 TI - Wilms tumors (nephroblastomas): report of 57 histologically proved cases. PMID- 4289193 TI - Cytomegalic inclusion disease following multiple blood transfusions. PMID- 4289192 TI - Studies on "nothing" dehydrogenase. PMID- 4289194 TI - Renin-angiotensin system in normal and toxemic pregnancies. II. Inactivation of angiotensin in normal pregnancy. PMID- 4289195 TI - Lack of feedback control of fatty acid synthesis in a transplantable hepatoma. PMID- 4289196 TI - Parallel changes in vivo in microsomal inorganic pyrophosphatase, pyrophosphate glucose phosphotransferase and glucose 6-phosphatase activities. PMID- 4289197 TI - Studies on activities of gluconeogenic enzymes in sheep liver. PMID- 4289199 TI - [Infectious mononucleosis caused by cytomegalovirus]. PMID- 4289198 TI - The role of free radicals of 4-hydroxy-3,5-diiodophenylpyruvic acid in the synthesis of thyroxine. PMID- 4289200 TI - Thermodynamic factors in the synthesis of two-stranded nucleic acids. PMID- 4289201 TI - Hybridization of dwarf hamster cells by UV-inactivated Sendai virus. PMID- 4289202 TI - Inhibition of SV40 T antigen formation by interferon. PMID- 4289203 TI - Different effects of chloramphenicol, dactinomycin, and streptovitacin A on synthesis of tumor and virion antigens in SV40 virus-infected cells. PMID- 4289204 TI - Chemical modification of the allosteric and catalytic sites of fructose 1,6 diphosphatase. PMID- 4289205 TI - The size of the polypeptide precursor of collagen hydroxyproline. PMID- 4289206 TI - [Periodontolyses: glomic disease or periodontal acro-syndrome]. PMID- 4289207 TI - Insulinoma and generalized islet cell hyperplasia in a patient with diabetes mellitus. PMID- 4289208 TI - Hemorrhagic femoral neuropathy. Report of a case due to anticoagulant. PMID- 4289209 TI - Respiratory disease in a group of intensively reared calves. PMID- 4289210 TI - Eosinopenia provoked by insulin in dogs in which the hypophysis has been substituted by transplants of salivary gland or adrenal tissue. PMID- 4289211 TI - The reflex mechanism which controls the release of ACTH stored in the hypophysis. PMID- 4289212 TI - Hemodynamics in acute renal failure. Pathogenesis of hyperkinetic circulation. PMID- 4289213 TI - Some effects of purified placental protein (human) on lipid and carbohydrate metabolism. PMID- 4289214 TI - Rate of blood glucose fall as a determinant factor in insulin-induced adrenocortical stimulation. PMID- 4289215 TI - Adrenal-mediated endometrial stimulation and withdrawal bleeding in the ovariectomized monkey. PMID- 4289216 TI - Mechanism of the suppression by iodide of the thyroidal 131-I release rate in the rat. PMID- 4289217 TI - Corticotrophs in the anterior pituitary glands of gonadectomized and thyroidectomized rats as revealed by electron microscopy. PMID- 4289218 TI - Sodium concentration and the effect of angiotensin II on ileal smooth muscle. PMID- 4289219 TI - Relationship between the chemical structure of thiazolidine acetic acid derivatives and the antiherpetic activity in human embryonic cell cultures. PMID- 4289220 TI - Effect of choline salicylates and some other analogues of salicylic acid on the replication of EMC virus in vitro. PMID- 4289221 TI - Immunochemical studies of angiotensin. PMID- 4289222 TI - Studies on Japanese B encephalitis virus vaccines from tissue culture. 8. Formalin inactivated OCT-wild strain vaccine. PMID- 4289223 TI - The sedimentation behavior of rhinovirus neutralizing activity in nasal secretion and serum following the rhinovirus common cold. PMID- 4289224 TI - Inactivation and density studies with PARA-adenovirus 7 (SV40-adenovirus "hybrid" population). PMID- 4289225 TI - Differential blockade of deoxyribonucleic acid synthesis by ethionine. PMID- 4289226 TI - Vitamin D-actinomycin D interactions in bone. An electron microscopic study of hypertrophy and hyperinvolution of osteoblasts. PMID- 4289227 TI - [Investigations on the chemical composition of Bordetella pertussis lipopolysaccharides in relation to the culture period]. PMID- 4289228 TI - [Effect of glucose and hyaluronic acid on hyaluronidase level in the supernatants of Clostridium perfringens type A]. PMID- 4289229 TI - [Studies on strains of poliomyelitis virus isolated in Poland during the 1959 1965 period. I. Biological properties of attenuated strains isolated from vaccinated humans]. PMID- 4289230 TI - [Studies on strains of poliomyelitis virus isolated in Poland during the 1959 1965 period. II. Interdependence between genetic markers of strains and their antigenic structure and neuropathological properties]. PMID- 4289231 TI - [Studies on strains of poliomyelitis virus isolated in Poland during the 1959 1965 period. 3. Characteristics of strains isolated following the vaccination activities]. PMID- 4289232 TI - [Introduction to 3 studies of valvular pathology]. PMID- 4289233 TI - [Study of 30 cases of aortic sigmoiditis during and following bacterial endocarditis. I. Etiologic and evolutive data]. PMID- 4289234 TI - [Study of 30 cases of aortic sigmoiditis during and following bacterial endocarditis. II. Clinical study]. PMID- 4289235 TI - [Contribution of phonocardiography to the selection of frequencies for the study of aortic insufficiencies]. PMID- 4289236 TI - [Methods and possibilites of the hearing aid]. PMID- 4289237 TI - [Pleuropulmonary staphylococcal infections in infants]. PMID- 4289238 TI - [Place of tuberculosis in amyloid disease]. PMID- 4289239 TI - [The preserving capacity of Clostridium perfringens toxin in sheep feces and intestinal contents]. PMID- 4289240 TI - Enzyme histochemical study on postmenopausal endometrium in symptom-free patients. PMID- 4289241 TI - The role of polymorphonuclear leukocyte lysosomes in tissue injury, inflammation and hypersensitivity. IV. The inability of leukocyte lysosomes to alter native collagen fibrils. PMID- 4289242 TI - Late sequelae of radiotherapy for Wilms' tumour in infancy. PMID- 4289243 TI - The metabolism of cholest-5-en-3-beta, 7-alpha-diol by rat-liver cell fractions. PMID- 4289244 TI - Urinary gonadotrophin excretion in patients with ulcerative colitis and Crohn's disease treated with A.C.T.H. and corticosteroids. PMID- 4289245 TI - Glycine metabolism. 3. A flavin-linked dehydrogenase associated with the glycine cleavage system in Peptococcus glycinophilus. PMID- 4289246 TI - Esterification of hydroxy compounds by fatty acid anhydrides. PMID- 4289247 TI - Preparation of brain polyphosphoinositides. PMID- 4289248 TI - Semiautomatic apparatus for milking mice. PMID- 4289250 TI - Further observations on Paget's disease of the nipple. PMID- 4289249 TI - Pathogenesis of virus-induced myeloid leukemia in mice. PMID- 4289252 TI - Histologic measurements and fine structure of biopsied sural nerve: normal, and in peroneal muscular atrophy, hypertrophic neuropathy, and congenital sensory neuropathy. PMID- 4289251 TI - [Angiotensin II in the diagnosis and therapy of disorders of adrenal mineralocorticoid secretion]. PMID- 4289253 TI - Studies of adenovirus-SV40 hybrid viruses. V. Evidence for linkage between adenovirus and SV40 genetic materials. PMID- 4289255 TI - [Myoblastoma (myoblastic myoma, granular-cell myoblastoma, granular-cell neurofibroma)]. PMID- 4289254 TI - [Sialo-mucous epidermoids]. PMID- 4289256 TI - [Effect of terms of culture growing of Clostridium perfringens types B and D on their immune properties]. PMID- 4289257 TI - [Pancreatic islet cell tumors in children]. PMID- 4289258 TI - [Enteritis caused by Clostridium perfringens]. PMID- 4289259 TI - The adrenal response of hamsters, gerbils and rats to exogenous corticotrophin or unilateral adrenalectomy. PMID- 4289260 TI - Impairment of the pituitary-adrenal response to acute stress in alloxan diabetes. PMID- 4289261 TI - Enzyme cytochemistry of iodine-131 irradiated thyroid gland. PMID- 4289262 TI - Morphologic and biochemical effects of Clostridium perfringens alpha toxin on intact and isolated skeletal muscle mitochondria. PMID- 4289264 TI - Surgical results in patients with ulcerative colitis treated with and without corticosteroids. PMID- 4289265 TI - Deep lymphatic system of the lower extremity. PMID- 4289263 TI - Ultrastructural studies on the lesion produced in skeletal muscle fibers by crude type A Clostridium perfringens toxin and its purified alpha fraction. PMID- 4289266 TI - The association of acetyl-coenzyme A carboxylase with the microsomal fraction of pigeon liver. PMID- 4289267 TI - Biochemical studies of the developing embryo. II. Studies on CO-2 fixation enzymes. PMID- 4289268 TI - Electrophoresis of mammalian aldehyde dehydrogenase. PMID- 4289269 TI - [Histochemical investigation of redox enzymes in experimental silicosis]. PMID- 4289270 TI - [Relationship between the rate of mitosis in the cells of a rat ascitic hepatoma and the cell complex size]. PMID- 4289271 TI - Association of a phaeochromocytoma and cerebral gliosarcoma with neurofibromatosis. PMID- 4289272 TI - Digital vascular response to angiotensin II in normotensive and hypertensive subjects. Evidence for a qualitatively abnormal response to angiotensin in essential hypertension. PMID- 4289273 TI - NADH-diaphorase activity in subcellular fractions of mouse tissues. PMID- 4289274 TI - Growth hormone releasing action of a Pseudomonas endotoxin (piromen). PMID- 4289275 TI - [Administration by the lymphatic route of radioactive isotopes for therapeutic purposes]. PMID- 4289277 TI - Chemodectomas of the carotid bifurcation. PMID- 4289276 TI - Radiological investigation of glomus jugulare tumours. PMID- 4289278 TI - Morphological changes of the brain following intrathecal application of contrast media. PMID- 4289279 TI - Intestinal Clostridium perfringens in rheumatoid arthritis and other connective tissue disorders. Studies of fecal flora, serum antitoxin levels and skin hypersensitivity. PMID- 4289280 TI - Dynamic investigation of urine, Na, K and Ca excretion after administration of tea, ACTH and ACTH with calcium in patients with articular disease. PMID- 4289281 TI - Traumatic hyphema: its clinical characteristics and failure of estrogens to alter its course. A double-blind study. PMID- 4289283 TI - Electron paramagnetic resonance and nuclear magnetic resonance as analytical tools. PMID- 4289282 TI - Retinal changes in human cytomegalovirus infection. An electron microscopic study. PMID- 4289284 TI - Choriocarcinoma in the Near East. Consanguinity as a possible etiologic factor. PMID- 4289285 TI - Urine steroid excretion in postmenopausal cancer of the breast. Response to corticotropin stimulation and dexamethasone suppression. PMID- 4289286 TI - Cytomegalic inclusion disease in childhood leukemia. PMID- 4289287 TI - Treatment and prognosis in Wilms' tumor. A study of 51 cases with special reference to the role of actinomycin D. PMID- 4289288 TI - Re-evaluation of the baroreceptor theory of control of renin secretion. PMID- 4289289 TI - Measurement of platelet adhesiveness including the use of diatomaceous silica (celite). AB - Methods of platelet adhesiveness to glass and celite have been developed. The technical merits of these methods have been compared with a method using adenosine diphosphate (ADP). The aspects of platelet stickiness measured by the various techniques may be somewhat different. Bearing this in mind, the reproducibility of the results using each of the three methods has been assessed on a series of healthy donors. PMID- 4289290 TI - Some plant extracts and their anti-amoebic effect. PMID- 4289291 TI - The use of some chlorinated hydrocarbon insecticides in central nervous system studies. PMID- 4289292 TI - Studies of a myxovirus recovered from patients with infectious hepatitis. II. Fine structure and electron microscopic demonstration of intracytoplasmic internal component and viral filament formation. AB - WB virus has been shown to have a fine structure which is characteristic of members of the mumps-NDV-parainfluenza group of viruses. Viral internal component has been demonstrated within the cytoplasm of infected cells. The incorporation of internal component into virus filaments at the cell surface has also been demonstrated. The evidence presented suggests that virus filament formation occurs by a process of invagination of the cell membrane about the coiled strands of internal component lying beneath the membrane. PMID- 4289293 TI - Studies on the leukocytosis and lymphocytosis induced by Bordetella pertussis. I. Radioautographic analysis of the circulating cells in mice undergoing pertussis induced hyperleukocytosis. AB - By the use of radioautographic techniques it was shown that the lymphocytosis induced by Bordetella pertussis in mice was not caused by an increased production of lymphocytes but was primarily due to the entry into the circulation of mature cells from tissue pools. The accompanying polymorphonuclear leukocytosis was due to both proliferation of myeloid elements and entry of mature cells from tissue reserves, with the former the predominant mechanism. PMID- 4289294 TI - Laryngotracheitis virus in chickens. A model for study of acute nonfatal desquamating rhinitis. AB - Infectious laryngotracheitis can be produced in chickens as an experimental model of severe nonfatal rhinitis and sinusitis. Inoculated intranasally into unanesthetized baby chicks it remains limited to the nasal fossa, produces acute desquamation of all nasal epithelia, results in functional recovery of the respiratory epithelium, but leaves important residual abnormalities. From the earliest recognizable lesions through 4(1/2) months' convalescence, the principal changes are as follows: 1. Initial lesions, or small syncytia of intranuclear "inclusions", first identifiable in the mucociliated cells of the shallowest portion of the epithelium at about 21 hr postinoculum (the inner surface of the maxillary conchal scroll). 2. Acute sloughing, (about 3 to 7 days), marked by: (a) spread of lesions from cell to cell via multinucleated "giant cells" which progressively slough and desquamate respiratory, olfactory, and sinus epithelia, epithelial neural elements and blood vessels; (b) appearance of numbers of eosinophilic leukocytes along the basement membrane at the sites of lesions just previous to sloughing; intensive infiltration of the submucosa with small lymphocytes after sloughing begins; (c) histochemical change in the intracellular mucus of the cells which comprise the syncytia: this mucus stains with Alcian blue alone when stained with AB-PAS; and (d) all cartilages of the maxillary conchae become flaccid, and the cell nuclei and matrix lose both basophilic and Alcian blue staining properties, effects which recede by about the 8th day. 3. Repair (about 8 to 21 days), marked by rapid initial spread of a sheet of epithelial cells over the infiltrated subrmucosa, appearance of numbers of plasma cells circulating in the tissues, formation of encapsulated secondary nodules, and mucosal adhesions. 4. Convalescence (about 1 to 4(1/2) months when experiments terminated), marked by functional restoration of the mucociliary lining of the nasal fossa. However, at 4(1/2) months eight specimens all show complete metaplasia of the olfactory organ (end nerves, supporting cells, and glands of Bowman) to mucociliated epithelium, all show abnormal formation and alignment of mucous acini, and about 50% have severe persistent sinusitis. PMID- 4289295 TI - Studies of the activity of diphtheria toxin. I. Poliovirus replication in intoxicated HeLa cells. AB - It has been demonstrated that a saturating dose of diphtheria toxin produced a 90% inhibition of polio-virus replication in HeLa cells. This inhibition was reflected in infectious viral RNA synthesis and in mature virus production. Toxin had no direct effect on virus particles or I-RNA, and poliovirus adsorption and eclipse appeared to be carried out normally in intoxicated cells. When toxin was given at various time intervals after infection, the amount of inhibition depended on the time of toxin addition. Toxin given before or immediately after infection gave maximum inhibition, while toxin given several hours after infection had little effect. The data suggest that toxin inhibits viral replication through its effect on protein synthesis. It is likely that a critical step in the viral replication cycle, the production of poliovirus-induced RNA polymerase, is inhibited, and possibly the synthesis of capsid protein. Ammonium salts and the aliphatic amines, glycamine and prolamine, prevented the inhibition of viral replication by toxin. The kinetics of the protective action of ammonium chloride and diphtheria antitoxin are remarkably similar. PMID- 4289296 TI - Persistent arteriovenous fistulae following chemotherapy of malignant trophoblastic disease. PMID- 4289297 TI - Siliceous urinary calculi in calves: prevention by addition of sodium chloride to the diet. AB - Urinary calculi were found in all but one of 14 calves given a ration associated with the formation of siliceous calculi. No calculi were found in a similar group of 14 calves given the same ration with sodium chloride added (4 percent). It is suggested that sodium chloride prevented calculus formation by in creasing water intake and urine volume, with a consequent reduction in the con-centration of silicic acid in the urine PMID- 4289298 TI - Problems in the management of renovascular hypertension. PMID- 4289299 TI - Pituitary-adrenal activation in rats with hereditary hypothalamic diabetes insipidus. PMID- 4289300 TI - Oestrogens in congenital adrenal hyperplasia. PMID- 4289301 TI - Ovarian endocrine activity in association with hormonally inactive neoplasia. PMID- 4289302 TI - Effect of vaccination against bovine myxovirus parainfluenza-3 before weaning and at the time of weaning on the natural history of respiratory disease in beef calves. PMID- 4289303 TI - Parainfluenza virus immunization. I. Antigenicity of two inactivated adjuvant parainfluenza type 3 vaccines. PMID- 4289305 TI - On the theory of silicosis. II. Quartz glass. PMID- 4289304 TI - Pituitary adrenal function during corticosteroid withdrawal in rheumatoid arthritis. PMID- 4289306 TI - Deficient red cell membrane /Na++K+/-ATPase in lead poisoning. PMID- 4289307 TI - Red cell membrane ATPase in workers exposed to inorganic lead. PMID- 4289308 TI - Embryonic antigens in liver tumors in rats. PMID- 4289309 TI - Studies on cellular resistance factors in polyoma virus infection. PMID- 4289310 TI - Effect of desoxyribonucleic acid (DNA) on survival and rat liver injury after irradiation. PMID- 4289311 TI - The influence of cellular immunity factors on oncogenesis in infection with polyoma virus in the Syrian hamster. Preliminary report. PMID- 4289312 TI - The effect of pure oxygen under different pressures in vivo on the anaerobic glycolysis of chrysoidine hepatoma in mice. PMID- 4289313 TI - The influence of the oncogenic polyoma virus on 2-phosphoenolpyruvate metabolism of mouse embryo cells grown in vitro. PMID- 4289314 TI - The effect of interferon-like materials on the metabolism of mouse embryo cell cultures infected with polyoma virus. PMID- 4289315 TI - Cytophotometric and cytochemical studies on the effect of actinomycin D and thioacetamide on rat liver cells. PMID- 4289316 TI - Glucose induced hyperglycemia and hyperinsulinemia. Persistence following removal of an islet cell adenoma. PMID- 4289317 TI - Histological studies on the cytomegalic inclusion body disease. PMID- 4289318 TI - Histochemical studies of the carbohydrate metabolism of the subfornical organ in the rat. PMID- 4289319 TI - Splenic pituitary homograft in the rat during gestation and lactation. PMID- 4289320 TI - Urinary pyrophosphate in normal subjects and in stone formers. AB - The urinary excretion of inorganic pyrophosphate was determined in nine normal subjects and also in eight patients with recurrent calcium-containing renal stones during varied levels of phosphate intake. The excretion of pyrophosphate and orthophosphate is virtually the same in the two groups at all levels of phosphate intake. It appears unlikely that a consistently reduced urinary excretion of pyrophosphate is a factor in the formation of urinary calculi. Pyrophosphate excretion rose and calcium excretion fell with increasing phosphate intake; this might be expected to have a beneficial effect in patients with recurrent calcium stones. PMID- 4289321 TI - Prolonged hyperadrenocorticotrophism and pigmentation associated with bronchial carcinoid tumour. PMID- 4289322 TI - The "air bronchiologram" and the solitary pulmonary nodule. Report of a case. PMID- 4289323 TI - Studies concerning the biological properties of zirconium silicate. PMID- 4289324 TI - Periodic dialysis in terminal uremia. PMID- 4289325 TI - [Changes in the lungs in children with cytomegaly]. PMID- 4289326 TI - Radiation-induced free polydeoxyribonucleotides in lymphoid tissues: a product of the action of neutral deoxyribonuclease (DNase 1). PMID- 4289327 TI - Mechanisms regulating adrenocortical secretion of aldosterone and glucocorticoids. PMID- 4289328 TI - [A rare case of concomitance of otogenic extradural abscess and hemorrhage into the left temporal lobe of the brain]. PMID- 4289329 TI - [Determination of cytochrome-c-oxidase in mitochondria of animal tissues]. PMID- 4289330 TI - The significance of mumps hemagglutinin inhibition titers in normal populations. PMID- 4289331 TI - Virucidal action of sea water. PMID- 4289332 TI - Differential renal function studies of the effects of angiotensin in normotensive and hypertensive patients. PMID- 4289334 TI - Thermal behaviour of silica and its application to dental investments. 1. A study of the polymorphic changes of silica. PMID- 4289333 TI - Histochemical observations on hydrolytic and oxidative enzymes in tooth supporting tissues in mature rodents. PMID- 4289335 TI - [The ACTH effect on the blood pressure and its role in experimental study of blood toxicity]. PMID- 4289337 TI - [Studies on the vicissitudes of polyoma virus in the parotid tumor induced by polyoma virus]. PMID- 4289336 TI - The role of adenohypophysial hormones and their target glands in isoquinoline dye hepatocarcinogenesis. PMID- 4289338 TI - The ultrastructural location of the periodate-Schiff reactive basement membrane at the dermoepidermal junctions of human scalp and monkey gingiva. PMID- 4289339 TI - Glomus jugulare tumors. Methods and difficulties of diagnosis and surgical treatment. PMID- 4289340 TI - [The effect of temperature adaptation on the proportion of mitochondria in fish muscle]. PMID- 4289341 TI - [Effects of cortisone and ACTH on the resistance of irradiated animals to bacterial toxins]. PMID- 4289342 TI - [The clinical picture and prophylaxis of "milker's nodes" in cattle-breeding farm workers]. PMID- 4289343 TI - The separation of infectious and autointerfering particles in vesicular stomatitis virus preparations. PMID- 4289344 TI - A virus-specific thymidine kinase in BHK-21 cells infected with herpes simplex virus. PMID- 4289345 TI - The effect of cytosine arabinoside on the replication of herpes simplex virus. PMID- 4289347 TI - Intracellular crystals in FL cells infected with poliovirus. PMID- 4289346 TI - On the apparent homology between DNA from polyoma virus and normal mouse synthetic RNA. PMID- 4289348 TI - The localization of SV40-induced neoantigen with ferritin-labeled antibody. PMID- 4289349 TI - A soluble antigen of the mammary tumor virus. PMID- 4289350 TI - Nonhemagglutinating complement-fixing V antigen of parainfluenza 1 virus (HVJ). I. The production of nonhemagglutinating V antigen in chick embryos infected with HVJ. PMID- 4289351 TI - Nonhemagglutinating complement-fixing V antigen of parainfluenza 1 virus (HVJ). II. The properties of nonhemagglutinating V antigen. PMID- 4289352 TI - Significance of triiodothyronine for thyroid hormone supply during stimulation. PMID- 4289353 TI - Pituitary-adrenal function in oral contraception. PMID- 4289354 TI - Viruses and oysters. PMID- 4289355 TI - Pituitary adenoma: results of combined surgical and radiotherapeutic treatment of 260 patients. PMID- 4289356 TI - Selective lymphopenia in man after intralymphatic injection of radioactive 131-I lipiodol. PMID- 4289357 TI - Metabolism of D-mannose in Aerobacter aerogenes: evidence for a cyclic pathway. AB - Kamel, M. Y. (Michigan State University, East Lansing), and R. L. Anderson. Metabolism of d-mannose in Aerobacter aerogenes: evidence for a cyclic pathway. J. Bacteriol. 92:1689-1697. 1966.-Evidence is presented which suggests a cyclic pathway for the constitutive utilization of d-mannose in extracts of Aerobacter aerogenes PRL-R3. d-Mannose is phosphorylated with d-glucose-6-phosphate to yield d-mannose-6-phosphate and d-glucose. d-Glucose-6-phosphate may be regenerated by isomerization of d-mannose-6-phosphate through d-fructose-6-phosphate, or by phosphorylation of d-glucose with adenosine-5'-triphosphate. The pathway involves the participation of four constitutive enzymes: d-glucose-6-phosphate isomerase, d-mannose-6-phosphate isomerase, a stereospecific d-glucokinase, and a phosphotransferase which phosphorylates d-mannose with d-glucose-6-phosphate, acetyl phosphate, or carbamyl phosphate. The absence of d-mannokinase (adenosine 5'-triphosphate:d-mannose phosphotransferase) activity in extracts of this organism suggests that the pathway may be of functional significance. Also, the pathway accounts for an apparent 2-epimerization of d-mannose to d-glucose that was observed in extracts. PMID- 4289358 TI - Enhancement of rhinovirus plaque formation in human heteroploid cell cultures by magnesium and calcium. AB - Fiala, Milan (University of Washington, Seattle), and George E. Kenny. Enhancement of rhinovirus plaque formation in human heteroploid cell cultures by magnesium and calcium. J. Bacteriol. 92:1710-1715. 1966.-A reproducible macroplaque assay for six M and three H strains of rhinoviruses has been developed in several human heteroploid cell lines. Plaques were produced only with suitable solidifying agents: purified agar (Ionagar, Agarose) or methylcellulose. Plaque development was greatly enhanced by increasing Mg(+2) to 30 to 40 mm. Diethylaminoethyl (DEAE) dextran also increased plaque sizes, and the effects of Mg(+2) and DEAE dextran were additive. In addition, Ca(+2) substituted for Mg(+2). The suitability of human heteroploid cell lines for rhinovirus plaque assay varied greatly, ranging from insensitivity through partial to complete sensitivity. This assay was six to seven times more sensitive than an end point tube assay. These results indicate that potentiation of plaque formation by Mg(+2) known for some enteroviruses can also be extended to the rhinovirus group of picornaviruses. PMID- 4289359 TI - Inhibition of Sindbis virus plaque formation by extracts of Escherichia coli. AB - Vilcek, Jan (New York University School of Medicine, New York, N.Y.), and John H. Freer. Inhibition of Sindbis virus plaque formation by extracts of Escherichia coli. J. Bacteriol. 92:1716-1722. 1966.-Extracts prepared from washed cells of Escherichia coli B by sonic treatment and subsequent filtration through a 0.45-mu membrane filter significantly inhibited plaque formation with Sindbis virus in cultures or primary chick embryo cells up to a dilution of 1:20,000. The inhibitor acted on the cells rather than directly on the virus. The inhibiting substance was nondialyzable. Treatment of crude extracts with nucleases, trypsin, chymotrypsin, pepsin, or ether had no effect on the activity. Treatment with pronase destroyed the virus-inhibiting effect. Extracts prepared from two strains of E. coli B and one strain of E. coli K-12 all showed inhibitory activity against Sindbis virus. The inhibitor was present in the cytoplasmic fraction of bacteria. It was also active against Sindbis virus in human cells and showed some activity against vesicular stomatitis and vaccinia viruses in different types of cells. Interferon was not shown to be involved in the inhibition, although actinomycin D partially reversed the inhibitory activity of the extracts. PMID- 4289361 TI - Electron microscopic observation of crystalline arrays of foot-and-mouth disease virus. PMID- 4289360 TI - Persistent cyclic herpes simplex virus infection in vitro. IV. Changes in the severity of the infections in the presence of antibody. AB - Hampar, Berge (National Institute of Dental Research, Bethesda, Md.). Persistent cyclic herpes simplex virus infection in vitro. IV. Changes in the severity of the infections in the presence of antibody. J. Bacteriol. 92:1741-1747. 1966.-The severity of persistent herpes simplex virus (HSV) infections maintained in the presence of viral antibody (AB) changed with time. These changes could be divided into three distinct phases during which the severity of the infections were maintained at low (phase 1), high (phase 2), and intermediate (phase 3) levels. Paralleling these changes was the appearance in the cultures of a new HSV variant which induced the formation of giant cells. The changes in the severity of the infections were attributable to three factors. The first was the presence in the cultures of virus-resistant cells. The second was the suppressive effects due to virus neutralization by the AB. The third was the inherent properties of each HSV variant which determined the amount of virus remaining in an infectious form in the presence of AB. Finally, the period of "exacerbation" in vitro (phase 2) was compared with recurrent episodes in human herpes infection. PMID- 4289362 TI - Inhibitory effect of heparin on Rous sarcoma virus. PMID- 4289363 TI - Zollinger-Ellison syndrome due to duodenal ectopic islet-cell tumour. PMID- 4289364 TI - Papovavirus SV40, adenovirus and their hybrids: transformation, complementation, and transcapsidation. PMID- 4289365 TI - [Role of O2 transfer activating enzymes in acclimatization to high altitude]. PMID- 4289367 TI - [Mixed tumors of the oral cavity]. PMID- 4289366 TI - [Adenogenous tumors of the hard and soft palate]. PMID- 4289368 TI - Primary tumor of the glomus pulmonale producing pulmonary stenosis in a Boston terrier. PMID- 4289369 TI - Surgical treatment of hepatic tumors by hepatic lobectomy. PMID- 4289371 TI - Structural relationships in the interaction of adrenocorticotropin with plasma proteins. PMID- 4289370 TI - The effects of halothane on rat liver mitochondria. PMID- 4289372 TI - Synthesis of isoleucine-5-tyrosine-8-angiotensin II and isoleucine-5 hydroxyproline-7-angiotensin II. PMID- 4289373 TI - Mossbauer spectroscopic evidence for low-spin iron in dehydrated metmyoglobin. PMID- 4289374 TI - Structure of amino acyl oligonucleotides from T-1 ribonuclease digests of soluble ribonucleic acid charged with serine, glycine, threonine, and alanine. PMID- 4289375 TI - Computation of metal binding in bi-metal--bi-chelate systems. PMID- 4289376 TI - Two unusual tumours of the chemoreceptor system with angiographic demonstration. PMID- 4289377 TI - Case reports. Glomus intravagale tumour. PMID- 4289378 TI - Bone sclerosis in multiple myeloma. PMID- 4289379 TI - [The effect produced by the pituitary-adrenal system on the permeability of histohematic barriers]. PMID- 4289380 TI - [Lights and shadows of the methods of determination of angiotensinemia. Comparative critical study]. PMID- 4289381 TI - [The action of angiotensin on urinary flow and on electrolyte excretion during normal pregnancy and the puerperium]. PMID- 4289382 TI - [Effects of the rapid infusion of angiotensin on separate renal clearances in renovascular and essential hypertension. I]. PMID- 4289383 TI - [Effects of the prolonged infusion of angiotensin on renal function and on electrolyte excretion in essential, renovascular and endocrine hypertension. II]. PMID- 4289384 TI - [Angiotensin intradermoreaction in patients with liver cirrhosis in the ascitic phase. Results and interpretation in relation to the pathogenesis of the altered hydrosaline metabolism in cirrhogenic liver diseases]. PMID- 4289385 TI - Three cases of poliomyelitis in children with polio virus type I in the cerebrospinal fluid. PMID- 4289386 TI - Method of treatment of rheumatoid arthritis in different countries. PMID- 4289387 TI - The brain phosphoinositides. PMID- 4289388 TI - Intraocular localization of copper by paramagnetic resonance spectroscopy. PMID- 4289389 TI - Kinetic constants of the human renin and human angiotensinogen reaction. PMID- 4289390 TI - [Complications in dental interventions in connection with local anesthesia]. PMID- 4289391 TI - Mouse trophoblastic cells in tissue culture. PMID- 4289392 TI - Prophylaxis of catheter-induced urinary tract infection in obstetric patients. PMID- 4289393 TI - Liver protein synthesis after partial hepatectomy and acute stress. PMID- 4289394 TI - Nucleoside triphosphate pyrophosphohydrolase of the plasma membrane of the liver cell. PMID- 4289395 TI - Sialography: a useful aid in diagnosing parotid tumors. PMID- 4289396 TI - [On a case of malignant mixed tumor of the submaxillary gland]. PMID- 4289397 TI - Intra-renal distribution of glucose-6-phosphatase: methodological and physiological considerations. PMID- 4289398 TI - Stable cell line of rat nephroma in tissue culture. PMID- 4289399 TI - Role of the pituitary and adrenals in cold and restraint induced liver nonprotein sulfhydryl depletion. PMID- 4289401 TI - Enumeration of VSV particles and a demonstration of their growth kinetics by electron microscopy. PMID- 4289400 TI - Biosynthesis of thiamine. Inhibition of thiamine phosphatase activity by pyridoxal. PMID- 4289402 TI - A micro-method for assay of neutralizing antibodies against parainfluenza virus types 1 and 3. PMID- 4289403 TI - The nature of antibody in swine naturally infected with japanese encephalitis virus. PMID- 4289404 TI - Impaired development of rat liver enzyme activities at birth after irradiation in utero. PMID- 4289406 TI - [Glomustumors of the middle ear and jugular fossa]. PMID- 4289405 TI - [Suprarenal adenoma with virilization and hyperaldosteronism in a 10-year-old girl]. PMID- 4289407 TI - [Some clinico-morphological peculiarities of viral neuroinfection in Odessa]. PMID- 4289409 TI - Effect of heparin on herpes simplex virus infection in the rabbit. PMID- 4289408 TI - Simultaneous inhibitory action of virus multiplication of interferon and some natural mucopolysaccharides (heparin, hyaluronic acid). PMID- 4289410 TI - Enhancing effect of human erythrocyte extracts on the susceptibility of monkey kidney cells to certain enteroviruses. PMID- 4289411 TI - Studies on the initial phases of poliovirus reproduction cycle. II. Comparative studies on HeLa and permanent monkey kidney cells. PMID- 4289412 TI - Studies on the initial phases of poliovirus reproduction cycle. 3. Action of fatty acids and tween 80. PMID- 4289413 TI - Thermal behaviour of silica and its application to dental investments. PMID- 4289415 TI - The nasopharyngeal angiofibroma. PMID- 4289414 TI - Radiological findings in acute necrotising encephalitis due to herpes simplex virus. PMID- 4289416 TI - Hepatic tumours in childhood. PMID- 4289417 TI - Hormonal control of rat testicular phospholipids. PMID- 4289418 TI - Studies on hyperproteinemia and proteinuria in rats bearing a mammosomatotropic tumor. PMID- 4289419 TI - Feedback mechanisms regulating pituitary ACTH secretion in rats bearing transplantable pituitary tumors. PMID- 4289420 TI - [Production of free radicals by irradiation in the longevity of the bones of the rat measured by paramagnetic electron resonance]. PMID- 4289421 TI - Reaction of OH radicals with nucleic acid bases--an E.S.R. study. PMID- 4289422 TI - Radical yields in some nucleic acid constituents. PMID- 4289423 TI - Digestion of potato starch by larvae of the flour beetle, Tribolium castaneum. PMID- 4289424 TI - Histidine in human vaginal fluid. PMID- 4289425 TI - Immunofluorescent and morphologic studies on swinepox. PMID- 4289426 TI - [Roentgen diagnosis of cylindromas of the mucous and salivary glands]. PMID- 4289427 TI - Plasma corticosteroids in mice, with special regard to sex difference in adrenocortical responsiveness to exogenous corticotrophin. PMID- 4289428 TI - [Some data on cystic-hemorrhagic disease in rats caused by the Rous sarcoma virus]. PMID- 4289429 TI - [Properties of the alistrim virus]. PMID- 4289430 TI - [Concentration of Japanese encephalitis virus by ammonium sulfate]. PMID- 4289431 TI - [Bacteriostatic and therapeutic efficiency of polymyxin in certain types of acute and chronic dysentery]. PMID- 4289432 TI - [Removal of an ectopic insuloma during a repeat operation]. PMID- 4289433 TI - Arteriography and chemotherapy in malignant trophoblastic disease. PMID- 4289434 TI - Generalized herpes simplex in newborns. PMID- 4289435 TI - Study of the cell bound inhibitor of polyoma virus haemagglutination. PMID- 4289436 TI - The virus inactivating capacity of sea water. PMID- 4289437 TI - [Abrikosov's granular cell tumor of the gluteal region]. PMID- 4289438 TI - Estrogen-induced arterial hypertension in the hibernating male toad, Bufo arenarum Hensel. PMID- 4289439 TI - [Action of cytochrome oxidase and succinodehydrogenase in the sartorius muscle of the frog extracted with glycerol]. PMID- 4289440 TI - Inhibitory effect of heparin on herpes simplex virus. AB - Nahmias, Andre J. (Boston University School of Medicine, Boston, Mass.), and Sidney Kibrick. Inhibitory effect of heparin on herpes simplex virus. J. Bacteriol. 87:1060-1066. 1964.-A substance inhibitory to herpes simplex virus was observed during experiments with leukocyte cultures. The component in the cultures responsible for this inhibition was identified as heparin. The minimal inhibitory concentration required to inhibit 30 to 300 tcd(50) of the virus in human amnion tissue culture was found to be 1 to 2 units per ml (10 to 20 mug/ml). This effect was confirmed with other strains of herpes simplex virus, other tissue-culture systems, and other media. The inhibitory activity of the heparin was found to be related to the sulfate groupings on the molecule. The effect of heparin appears to be on the virus, rather than on the cell. The virus is not inactivated, however, and the heparin-virus "complex" is readily dissociable on dilution. Heparin was shown to affect viral infection in its earliest phase, probably at the primary electrostatic attachment of virus to cell. The import of these and related observations on common virological laboratory procedures and the possible biological significance of our findings are discussed. PMID- 4289442 TI - Metabolism of mannitol by Coccidioides immitis. AB - Lones, George W. (National Institute of Allergy and Infectious Diseases, U.S. Public Health Service, Bethesda, Md.), and Carl Peacock. Metabolism of mannitol by Coccidioides immitis. J. Bacteriol. 87:1114-1117. 1964.-Strain M-11 of Coccidioides immitis was found to utilize mannitol for growth in the mycelial form but not in the spherule form. Cell-free extracts of both forms, grown on glucose, were capable of reducing nicotinamide adenine dinucleotide with mannitol 1-PO(4) but not with mannitol. The extracts accomplished a rapid oxidation of reduced nicotinamide adenine dinucleotide by fructose-6-PO(4), the expected product of mannitol-1-PO(4) oxidation. Fructose was inactive. Paper electrophoresis and chromatography with several solvent systems demonstrated a substance in extracts of both mycelium and spherules having a migration consistent with that of mannitol. PMID- 4289441 TI - Heterogeneity of apparently complete poliovirus particles. AB - Tumilowicz, Joseph J. (Children's Hospital of Philadelphia, Philadelphia, Pa.), and Klaus Hummeler. Heterogeneity of apparently complete poliovirus particles. J. Bacteriol. 87:1105-1113. 1964.-A chromatographic procedure was developed for separating the N from the H complement-fixing antigen of poliovirus. This procedure concomitantly effected some separation of classes of N particle. The ratio of physical virus particles (PVP) to plaque-forming units (PFU) in N reactive fractions varied from 6 to 51. Fractions with the lowest PVP-PFU ratios represented a considerable enrichment of PFU, when compared with the original ratio in each experiment. A direct relationship was found between the ratio of complement-fixing units of N antigen [CFU(N)] to 10(10) PVP and the ratio of PFU to 10(10) PVP for most of the N-reactive fractions. Large differences among the PVP-CFU(N) ratios, along with relatively constant PFU-CFU(N) ratios for most of the N fractions, indicated that N antigen is not distributed equally among non-H particles. Two possibilities, both compatible with the results, were discussed for the manner in which N antigen might be distributed. An absolute value of 10(7) PVP-CFU(N) was proposed for particles with a PVP-PFU ratio of 1. PMID- 4289443 TI - Mouse salivary gland virus plaque assay on a stable line of mouse embryo cells. PMID- 4289444 TI - Polymyxin agar as an adjunct in the isolation of El Tor vibrios. PMID- 4289445 TI - The alteration of serotonin metabolism to 5-hydroxytryptophol by ethanol ingestion in man. PMID- 4289447 TI - The metabolism of gamma-aminobutyric acid (GABA) in the lobster nervous system. II. Succinic semialdehyde dehydrogenase. PMID- 4289446 TI - The metabolism of gamma-aminobutyric acid (GABA) in the lobster nervous system. I. GABA-glutamate transaminase. PMID- 4289448 TI - The localization of placental enzymes with the electron microscope. PMID- 4289449 TI - Evaluation of growth and of endocrine systems in testosterone-corticosteroid treated patients with aplastic anemia. PMID- 4289450 TI - A comparison of skeletal growth and maturation in undernourished and well nourished girls before and after menarche. PMID- 4289451 TI - Intrarenal hemodynamic changes following acute partial renal artery occlusion. PMID- 4289452 TI - Diagnostic problems of choriocarcinoma and related trophoblastic neoplasms. PMID- 4289453 TI - Metastatic nephroblastoma of the mandible. PMID- 4289454 TI - [Enzymohistochemical study on "psammomatous carcinoma" of the breast]. PMID- 4289455 TI - [Thecoma and fibroma of the ovary. (3 case contributions and considerations on the more recent classification of functional tumors)]. PMID- 4289456 TI - [On granular cell myoblastomyoma of the gingiva (congenital epulis)]. PMID- 4289457 TI - The galactose tolerance test as a measurement of the redox potential of the liver. PMID- 4289458 TI - ACTH action on reductive pathway in the quartered rat adrenal. PMID- 4289459 TI - Effect of a new hypotensive drug, ST155, on the systemic circulation. PMID- 4289460 TI - Adjuvant therapy for advanced ovarian malignancy. PMID- 4289461 TI - [On a syndrome with nevoid skin atrophies. (Disseminated neviform atrophodermia)]. PMID- 4289462 TI - Red-cell metabolism in hereditary spherocytosis. PMID- 4289463 TI - Isolation and activity of propionin A, an antiviral polypeptide from Propionibacteria. PMID- 4289465 TI - Malignant anal lesions. PMID- 4289464 TI - Malignancies in African children how do these differ from malignancies in the United States? PMID- 4289466 TI - [Diseases of the peripheral nervous system at the Talitsa lumber cutting of the "Sverdles" combine]. PMID- 4289467 TI - Ultrastructural localization of nucleoside triphosphatase in Langerhans cells. PMID- 4289468 TI - Studies in the biochemistry of skin. IV. Some properties of mitochondria isolated from the epidermis of the adult rat. PMID- 4289469 TI - Metabolic responses of white rats to balanced and imbalanced protein fed with different carbohydrates in 15 percent and 5 percent fat diets. PMID- 4289470 TI - [Production of ammonia and catabolism of purine nucleotides in the guinea pig leukocyte]. PMID- 4289472 TI - Reaction of infectious RNA with mammalian cells. I. Attachment to cells. PMID- 4289471 TI - [Corticosteroid therapy and the function of the adrenal cortex]. PMID- 4289473 TI - [On the peripheral components of the adynamia of Addison's disease]. PMID- 4289474 TI - [Determination of the effectiveness of virus detoxication using tissue cultures]. PMID- 4289475 TI - Growth rate and terminal cell density of bovine fibroblastic cells morphologically transformed in vitro by Rous sarcoma virus. PMID- 4289476 TI - Evidence for early synthesis of Rous sarcoma virus in bovine fibroblasts. PMID- 4289477 TI - Clonal analysis of bovine cells morphologically transformed in vitro by Rous sarcoma virus. PMID- 4289478 TI - Kinetic and measurement of the renin-antirenin system. PMID- 4289479 TI - Functioning metastases from an islet cell tumor of the pancreas. PMID- 4289480 TI - Studies on circulation and elimination of viruses in the guinea pig. PMID- 4289481 TI - Children's age and stature estimated from femur diameter. PMID- 4289482 TI - Local and systemic therapy of pseudomonas septicemia in burned mice. PMID- 4289483 TI - Histochemical studies of enzymatic patterns during experimental carcinogenesis in the mouse parotid gland. PMID- 4289484 TI - Screening data from the Cancer Chemotherapy National Service Center screening laboratories. XXXIX. Plant extracts. PMID- 4289485 TI - [Paper electrophoretic separation of seromucoids in perchloric acid filtrate]. PMID- 4289486 TI - Perianal skin amebiases. PMID- 4289487 TI - A mechanical aid to control bladder infection and function using indwelling catheters. PMID- 4289488 TI - A quantified periodic acid-Schiff reaction in normal and leukemic leukocytes. PMID- 4289489 TI - Microangiopathic hemolytic anemia in carcinoma of the stomach. PMID- 4289490 TI - Extraction and bioassay of renin from kidneys of sodium depleted and sodium loaded rats. PMID- 4289491 TI - Bilateral nephroblastoma in two sisters. PMID- 4289492 TI - Some unusual adult male urogenital tumors with dysontogenetic features. Reports of mesonephroma, Mullerian carcinosarcoma, transitional cloacogenic carcinoma and nephroblastoma. PMID- 4289494 TI - Cell culture and infectious hepatitis. PMID- 4289493 TI - Detroit 6 cells and infective hepatitis. PMID- 4289495 TI - Effect of aldosterone and salt intake on renal and pressor actions of angiotensin. PMID- 4289496 TI - "Spontaneous" changes in the brains of monkeys used for vaccine production. PMID- 4289497 TI - [Contribution of cytologic examinations in the diagnosis of mammary and extra mammary Paget's disease]. PMID- 4289498 TI - Circadian pattern of plasma 17-hydroxycorticosteroid: alteration by anticholinergic agents. AB - Atropine, administered to cats just prior to the time of the expected circadian rise in levels of 17-hydroxycorticosteroid in plasma, blocks this rise. Atropine does not alter this circadian pattern when administered at other times in the circadian cycle. Results similar to those obtained with atropine have been observed with short-acting barbiturates. Dibenzyline administered just prior to the time of the expected circadian rise is ineffective in blocking this rise. These findings support the hypothesis that the circadian pattern of plasma 17 hydroxycorticosteroid levels reflects activation, by the central nervous system, of the hypothalamicpituitary-adrenal axis during a "critical time period" in the circadian cycle. PMID- 4289499 TI - Muscle-spindle histochemistry. AB - Reduced nicotinamide adenine dinucleotide tatrazolium reductase is abundant in cat intrafusal muscle fibers, whereas in the toad its activity is equal to that in extrafusal fibers. Spindles of both species contain little fat. In sections stained for adenosine triphosphatase bound to myofibrils, two types of intrafusal muscle fibers appear in spindles of both the cat and toad. PMID- 4289500 TI - Hydroxyquinone:NADH oxidoreductase from Aspergillus fumigatus. I. Isolation and properties of the enzyme. PMID- 4289501 TI - Hydroxyquinone:NADH oxidoreductase from Aspergillus fumigatus. II. Kinetic studies on the enzyme. PMID- 4289502 TI - Immunization of guinea pigs with foot-and-mouth disease virus subjected to photodynamic inactivation. PMID- 4289503 TI - Influence of drugs on vasoactive peptides and amines in perfused human placenta. PMID- 4289504 TI - Pharmacological control of lipid mobilization and transport. PMID- 4289505 TI - Influence of thyroid and adrenocorticotrophic hormones and of genetic factors on cholesterol metabolism in the rat. PMID- 4289506 TI - Sites of avian leukosis virus multiplication in congenitally infected chickens. PMID- 4289507 TI - Physiologic disposition and intracellular localization of isometamidium. PMID- 4289508 TI - Nucleolar changes in KB tumor cells infected with herpes simplex virus. PMID- 4289509 TI - Studies on composition and leakage of proteins and esterases of normal rat liver and Morris Hepatoma 5123 t.c. PMID- 4289511 TI - [Peridural anesthesia in myelography with water-soluble iodized contrast medium. Preliminary note: technic, advantages, results]. PMID- 4289510 TI - Anogenital Paget's disease. PMID- 4289512 TI - [Histoenzymology of the human endocrine pancreas]. PMID- 4289513 TI - The relation of various enzymes to cellular membranes. PMID- 4289514 TI - Cytochemical studies of hydrolytic and oxidative enzymes in sections and isolated cells from the endocrine pancreas of guinea-pigs. PMID- 4289515 TI - Histochemical method for localization of cyclic 3',5'-nucleotide phosphodiesterase. PMID- 4289516 TI - [The effects of immediate cooling of the skin following scalding on the enzyme action in kidney and liver]. PMID- 4289517 TI - Iodinated 5- and 8-hydroxyisoquinolines as potential amebicides. PMID- 4289518 TI - Brain tumors with tuberous sclerosis. PMID- 4289519 TI - The hormonal treatment of acroparaesthesia and night cramps. PMID- 4289520 TI - The outside influence on patient care. PMID- 4289521 TI - [On the method of homoplastic replacement of the knee joint]. PMID- 4289522 TI - A unique hyperfine ESR spectrum in mouse neoplasms analyzed by computer simulation. PMID- 4289523 TI - Genomic modifications in cell line cultures chronically infected with a myxovirus. PMID- 4289524 TI - Inhibition of viral replication by interferons with different molecular weights. PMID- 4289525 TI - Susceptibility of HeLa cells in S-phase to inhibition of DNA synthesis by poliovirus infection. PMID- 4289526 TI - Production of interferon in embryonated eggs and in cell cultures infected with simian virus 5. PMID- 4289527 TI - Induction of interferon in mice infected with Toxoplasma gondii. PMID- 4289528 TI - In vitro and in vivo antiviral action of an interferon-like substance induced by Toxoplasma gondii. PMID- 4289529 TI - Effects of lanthanide chlorides on selected enzymes. PMID- 4289530 TI - Ribonucleic acid of foot-and-mouth disease virus: an ultrasensitive plaque assay. PMID- 4289531 TI - Cytomegalovirus infections with reference to isolations from lymph nodes and blood. PMID- 4289532 TI - [The Gardner syndrome]. PMID- 4289534 TI - [Multiplication of the chicken sarcoma virus in the mouse embryonic tissue]. PMID- 4289533 TI - [Hormonal variations in urogenital tuberculosis]. PMID- 4289535 TI - [Effects of neonatal thymectomy on cystic disease induced in rats by Rous sarcoma virus]. PMID- 4289536 TI - Hydroxylamine as a possible intermediate in nitrate reduction by Bacterium anitratum (B5W). PMID- 4289537 TI - Production of varicella-zoster CF antigen in a continuous line of grivet monkey kidney cells. PMID- 4289538 TI - Long-term cultivation of human and bovine fibroblastic cells morphologically transformed in vitro by Rous sarcoma virus. PMID- 4289539 TI - Infusion chemotherapy in hepatoma and metastatic liver tumors. PMID- 4289540 TI - Immunoelectrophoretic analysis of several strains of Entamoeba histolytica. PMID- 4289541 TI - Ammonia production by the Bacterioides sp. used to support the propagation of Entamoeba histolytica in the CLG medium. PMID- 4289542 TI - Effects of different species of bacteria on the pathology of enteric amebiasis in monocontaminated guinea pigs. PMID- 4289543 TI - [Average cocipital evoked potentials and lesions of the optic nerve]. PMID- 4289544 TI - [Comparative actions of ascorbic acid, reduced glutathione and NADH on ammoniemia in cirrhotic patients]. PMID- 4289545 TI - Studies on the anti-tumour activity of aliphatic aldehydes. I. The mechanism of inhibition of amino acid incorporation into protein of Yoshida ascites hepatoma cells. PMID- 4289546 TI - [Histochemical enzyme studies on the Harder's gland of the rabbit]. PMID- 4289547 TI - Peroneal-nerve irritation associated with cystic lateral meniscus of the knee. A report of two cases. PMID- 4289548 TI - Hypophosphatasia in monozygotic twins. A case report. PMID- 4289549 TI - Posterior interosseous nerve palsy due to rheumatoid arthritis. PMID- 4289551 TI - ACTH antibodies in patients receiving depot porcine ACTH to hasten recovery from pituitary-adrenal suppression. AB - Six patients who had experienced prolonged steroid-induced pituitary-adrenal suppression were treated with 100 U of depot procine ACTH every 2 to 4 days for several months. Such treatment did not hasten the recovery of normal pituitary adrenal function compared with the rate of recovery of a group of similarly suppressed patients who received no depot ACTH. Eight of nine patients who received prolonged courses of depot porcine ACTH developed antibodies to ACTH that cross-reacted with endogenous ACTH, binding it in the circulation in inactive form and retarding its removal from the circulation. The presence of such antibodies did not in itself grossly alter pituitary-adrenal interrelationships. PMID- 4289552 TI - Psychological stress in cleft palate etiology. PMID- 4289550 TI - Studies on the epidemiology of Escherichia coli infections. V. Factors influencing acquisition of specific serologic groups. AB - Stool carrier rates of Escherichia coli serogroups 4, 6, and 75 were determined on admission and discharge for 190 patients. Persons who were in the hospital 3 weeks or longer had an intestinal carrier rate of 46% compared to a rate of 28% in individuals who had no recent hospital contact. Treatment with broad spectrum antibiotics increased the susceptibility for acquisition of certain specific serologic groups. This was apparently not related to replacement of sensitive E. coli by drug-resistant forms. Studies were made to determine the environmental source for colonization of hospitalized patients and the risk of urinary infection in stool carriers of these strains. A survey of inanimate objects of medical and urological wards demonstrated infrequent isolation of 04, 06, and 075, indicating that extraintestinal foci were an unlikely source for hospital acquired E. coli. Hemagglutination titers with determination of group-specific O antibody failed to demonstrate any deficiency in hospitalized patients who became colonized with certain coliforms. Similarly, no significant deficit in group specific serum antibody was found in patients who were community carriers of E. coli 04, 06, or 075. Despite a high rate of acquisition of E. coli serogroups 4, 6, and 75 in the stools of hospitalized patients, only those patients undergoing urinary tract manipulation developed bacteriuria. PMID- 4289553 TI - The morphologic characteristics of 19S antibody. PMID- 4289554 TI - The pathogenesis of Theiler's GD VII encephalomyelitis virus infection in mice as studied by immunofluorescent technique and infectivity titrations. PMID- 4289555 TI - Thermostable Clostridium perfringens as cause of food poisoning outbreak. PMID- 4289556 TI - [Epidemiological study of poliomyelitis in application of antigenic marker (McBride test)]. PMID- 4289557 TI - [The correlation of electroencephalographic and clinical findings in pancreatic islet cell tumors]. PMID- 4289559 TI - Differential diagnosis of arteriovenous aneurysms and brain tumors on the basis of the angiographic pattern. PMID- 4289558 TI - Effect of ischaemia on adrenocortical corticosterone secretion in the rat. PMID- 4289560 TI - Recurrent jaundice in pregnancy. II. A study of the estrogens and their conjugation in late pregnancy. PMID- 4289561 TI - Visualization of the choroid plexus on the technetium 99m brain scan. Clinical significance and blocking by potassium perchlorate. PMID- 4289562 TI - Sampling of enamel particles by means of strong acids for density measurements. PMID- 4289563 TI - Enzymes of glycolytic cycle in periodontal tissues of the guinea pig. PMID- 4289564 TI - Influence of angiotensin, vasopressin or changes in flow rate on vasoconstriction, changes in volume and [3H]-noradrenaline release following postganglionic sympathetic nerve stimulation in the isolated cat spleen. PMID- 4289565 TI - Effect of infantile malnutrition on growth. PMID- 4289566 TI - Renin, angiotensin, aldosterone and hormonal regulation of arterial pressure and salt balance. Introductory remarks. PMID- 4289567 TI - Biochemistry and kinetics of the renin-angiotensin system. PMID- 4289568 TI - Intrarenal function of angiotensin. PMID- 4289569 TI - Humoral factors in the regulation of renal sodium excretion. PMID- 4289570 TI - Clinical study on the dephosphorylation of adenosine triphosphate by human sera, with special references to serum acid ATPase activity in essential hypertension. PMID- 4289571 TI - Erythropoietin release associated with Wilms' tumor. PMID- 4289572 TI - Cystosarcoma phyllodes. PMID- 4289573 TI - [On the influence of methotrexate on the nucleotide content of the mastocytoma P 815]. PMID- 4289574 TI - [Peripheral toxic neuropathy caused by gummy adhesives]. PMID- 4289575 TI - A method for routine determination of plasma triglycerides. PMID- 4289578 TI - A new system for the biological determination of the sedimentation constant. PMID- 4289576 TI - Coccidiosis in the guinea pig small intestine due to a Cryptosporidium. PMID- 4289577 TI - Host range studies of two porcine polioencephalomyelitis viruses. PMID- 4289579 TI - Fluorescent lamp stabilizer for filter fluorometers. PMID- 4289580 TI - Determination of nucleic acids with concentrated H-2-SO4. II. Simultaneous determination of ribo- and deoxyribonucleic acid. PMID- 4289581 TI - Reactivation of herpetic keratitis in rabbit. II. Repeated reactivations in the same host. PMID- 4289582 TI - Nucleic acid interactions. VI. Effects of steroidal diamines. PMID- 4289583 TI - The synthesis of [1,2-3H]vitamin D3 and the tissue localization of a 0.25-mu-g (10 IU) dose per rat. PMID- 4289585 TI - Influence of phyrophosphate on modification of myosin by beta-hydroxyethyl-2,4 dinitrophenyl (HEDD). PMID- 4289584 TI - Properties of Rhodospirillum rubrum subchromatophore particles obtained by treatment with Triton X-100. PMID- 4289586 TI - Tritiated thymidine incorporation into KB cells infected with parainfluenza 3 virus. PMID- 4289587 TI - [Mixed salivary gland tumors]. PMID- 4289588 TI - Immunization programs for dairy cattle. PMID- 4289589 TI - [Therapy of anterior pituitary lobe insufficiency]. PMID- 4289590 TI - Histochemical mapping of succinic dehydrogenase and cytochrome oxidase in the spinal cord, medulla oblongata and cerebellum of squirrel monkey (Saimiri sciureus). PMID- 4289591 TI - Histochemical mapping of succinic dehydrogenase and cytochrome oxidase in the pons and mesencephalon of squirrel monkey (Saimiri sciureus). PMID- 4289593 TI - Serum placental lactogen levels during pregnancy and in trophoblastic disease. PMID- 4289592 TI - A sensitive radioimmunoassay for plasma ACTH levels. PMID- 4289594 TI - Disturbance of pituitary-adrenal interrelationships in benign intracranial hypertension (pseudotumor cerebri). PMID- 4289595 TI - Growth behavior of spontaneous hepatoma and OAT-induced hepatoma in mice. PMID- 4289596 TI - A renin-like substance in the human placenta. PMID- 4289597 TI - Enzyme histochemistry of a masculinizing arrhenoblastoma. PMID- 4289598 TI - Clinical malignancy of endocrine tumors of the ovary and dysgerminoma. PMID- 4289600 TI - Genital herpes simplex infection. Virologic and cytologic studies. PMID- 4289599 TI - Surgical treatment of squamous-cell carcinoma of the vulva. PMID- 4289601 TI - Endemic outbreak of canine hepatitis (Rubarth's disease) among bears. PMID- 4289602 TI - [On the late sequelae of infectious canine hepatitis]. PMID- 4289603 TI - [Venous blood angiotensin in pregnancy]. PMID- 4289604 TI - Intracellular localization of the golgi apparatus-associated phosphatase in rat kidneys. PMID- 4289605 TI - In vitro test for sensitivity of tumor to carcinostatic agents. PMID- 4289606 TI - Histochemical studies on enzymes in lung tumors. I. Enzyme activities in human lung cancer. PMID- 4289607 TI - Histochemical studies on enzymes in lung tumors. II. Enzyme activities in mouse and rat lung tumors induced by 4-nitro-quinoline 1-oxide. PMID- 4289608 TI - Primary mass culture of Yoshida sarcoma and rat ascites hepatomas. PMID- 4289609 TI - On histochemical studies of the various organs of spontaneously hypertensive rats. PMID- 4289610 TI - [Study on allergy to intestinal flora. 1. Toxin activity of anticlostolysin theta in various diseases]. PMID- 4289611 TI - [Study on allergy to intestinal flora. 2. Experimental renal lesions induced by sensitization with Clostridium welchii toxin]. PMID- 4289612 TI - Progressive atrophy of skeletal muscles. Tips on differential diagnosis. PMID- 4289613 TI - Peripheral neuropathy. PMID- 4289614 TI - Clinicopathologic conference. Abdominal pain relieved by food. PMID- 4289615 TI - [Laboratory characteristics of variola strains isolated during the smallpox epidemic in Poland in 1963]. PMID- 4289616 TI - [Diagnosis and differential diagnosis of leprosy with reference to our observations in the Vietnam Democratic Republic]. PMID- 4289617 TI - Bovine ulcerative mammillitis caused by a herpesvirus. PMID- 4289618 TI - [Laryngeal papilloma (current status of the problem)]. PMID- 4289619 TI - [Chemodectomas or chimiodectomas of jugular system]. PMID- 4289620 TI - Polyoma virus. 3. On the nature of the virus receptors on the mouse embryo cells. PMID- 4289621 TI - Hemodynamic effects of angiotensin during surgical anesthesia. PMID- 4289622 TI - Quantitative studies on fabrics as disseminators of viruses. II. Persistence of poliomyelitis virus on cotton and wool fabrics. AB - The length of time that poliovirus could be recovered from wool gabardine and blanket, and from cotton sheeting, terry cloth, and knit jersey fabrics was determined under conditions of controlled temperature and humidity (25 C in 35 and 78% relative humidities). Three types of exposure of the fabrics to viruses were used: direct contact, aerosol, and virus-containing household dust having a high content of textile fibers. When held in 35% relative humidity, virus persisted for 20 weeks on wool fabrics, but only 1 to 4 weeks on cotton fabrics. At this relative humidity, virus titers on wool fabrics decreased rapidly to low but detectable levels which persisted for long periods of time, whereas in 78% relative humidity the decrease in virus titer was less rapid, but the period of viral persistence was shorter. Generally, virus titers on cotton fabrics held in both relative humidities decreased exponentially to an undetectable level. The method of exposure to virus had a definite effect on the duration of viral persistence on a given fabric. Virus contained in household dust was least stable. PMID- 4289623 TI - Influence of salts on foot-and-mouth disease virus. AB - The effect of sodium and magnesium chloride in 1 and 2 m concentration at temperatures of 37 and 50 C on type C, strain 149, foot-and-mouth disease virus during storage for 6 days was studied. The exclusively passaged cattle strain and its tissue culture-adapted line were compared. Preparations of the various chemicals and their concentrations were made directly in suspensions of the virus, which, together with untreated control virus suspensions, were stored at indicated temperatures and tested daily for concentration of virus present. Both 1 and 2 m concentrations of Mg markedly slowed the degradation of the bovine passaged virus, as compared with untreated virus stored at 37 or 50 C. Such was not the case with 1 and 2 m concentrations of Na at 37 and 50 C, in which instance the treated virus was degraded faster than the untreated controls at 37 C, and but slightly influenced at 50 C. The tissue culture-adapted virus at the 25th passage was not stabilized by any concentration of chemical additive either at 37 or 50 C, except for 1 and 2 m concentrations of Na at 37 C, which partially retarded degradation of the virus. After 91 passages of the virus in tissue culture, only a suggestion of the influence of 1 and 2 m concentrations of Na at 37 C remained to show a stabilizing effect. These responses tend to separate the bovine-passaged virus from the tissue culture-adapted virus under the conditions of this study. PMID- 4289624 TI - Survival and recovery of enterovirus from foods. AB - Type 1 poliovirus and type B1 and B6 coxsackieviruses added to eight commercial frozen or convenience foods before storage at room temperature, 10 C, and -20 C were still viable after various intervals of time up to 1 week, 1 month, and 5 months, respectively. Infectivity titers were determined in monkey kidney tissue culture. Decomposition which took place in food stored at room temperature did not affect the survival of virus, and antibiotics controlled bacterial growth during assay. A rapid, significant reduction in type B6 coxsackievirus was observed in cole slaw. Preliminary data indicate that sodium bisulfite could be the responsible ingredient. A less rapid reduction of type 1 poliovirus and type B6 coxsackievirus was found in hashed brown potatoes when stored at 10 C. PMID- 4289625 TI - Synovial sarcomas of the neck. PMID- 4289626 TI - Severity of smallpox and virulence of causative virus strains. PMID- 4289627 TI - [Infantile gastroenteritis. Research on a viral etiology]. PMID- 4289628 TI - The effect of lethal doses of x-irradiation on the enzymatic activity of mitochondrial cytochrome c. PMID- 4289629 TI - The effect of o,p-DDD in the chicken. PMID- 4289630 TI - Stress stimulation of drug metabolism in the rat. PMID- 4289631 TI - Oligosyndactylism, an early embryonic lethal in the mouse. PMID- 4289632 TI - [Case of ACTH-hypersensitivity]. PMID- 4289633 TI - A re-evaluation of the skin test of herpes simplex virus. PMID- 4289634 TI - [Virus encephalitis]. PMID- 4289635 TI - [Pharyngoconjunctival fever and epidemic keratoconjunctivitis]. PMID- 4289636 TI - [Hospital mortality and morbidity of an internal medicine department at Abidjan]. PMID- 4289637 TI - [Morphological changes of skin in the case of contagious pustulous dermatitis in sheep]. PMID- 4289638 TI - [Observations of an enzootic of infectious pustular dermatitis in sheep]. PMID- 4289639 TI - Attempts to demonstrate infectious virus in human and bovine fibroblastic cells morphologically transformed in vitro by Rous sarcoma virus. PMID- 4289640 TI - The mechanism of the push and pull principle. VII. Endocrine effects of chlordiazepoxide, diazepam and guanethidine. PMID- 4289641 TI - An isolated guinea pig kidney perfusion preparation for studying the effect of pharmacologically active substances. PMID- 4289643 TI - Localization of nucleic acids in the cells of a monkey tissue culture during the development of the vegetative form of the SV40 virus. PMID- 4289642 TI - Environmental factors influencing the hyperfine structure of manganous low temperature electron paramagnetic resonance spectra. AB - Hyperfine structure is observed in low temperature (T = -180 degrees C) EPR (electron paramagnetic resonance) spectra of a number of solutions containing Mn(++) ions 13, 15) which have characteristics in common with low temperature EPR spectra from biological substances such as mitochondria and microsomes (1-4). This investigation is an attempt to understand the features of these signals in terms of the molecular environment of the manganous ion, and a qualitative explanation for the observations reported here is advanced in terms of the amount of axial distortion of a manganese hydrate in different environments. PMID- 4289645 TI - Ultrastructure of a chemodectoma. PMID- 4289644 TI - Femoral neuropathy from heparin hematoma. Report of two cases. PMID- 4289646 TI - Tarsal tunnel syndrome. PMID- 4289647 TI - Immunologic studies of adrenocorticotropic hormone (ACTH): effect of carboxypeptidase digestion on biologic and immunologic activities. PMID- 4289648 TI - Reduced aldosterone excretion in patients with autonomic insufficiency. PMID- 4289649 TI - Diurnal variation of plasma 17-hydroxycorticosteroids in children. PMID- 4289650 TI - The preparation and characterization of mitochondria from developing red blood cells. PMID- 4289651 TI - Cold doesn't affect the "common cold" in study of rhinovirus infections. PMID- 4289652 TI - Dactinomycin in Wilms' tumor. PMID- 4289653 TI - Pancreatic islet cell tumours. PMID- 4289654 TI - Mesenchymal hamartoma of the liver. Report of a rare case. PMID- 4289655 TI - [A case of solitary renal cyst associated with Wilms' tumor]. PMID- 4289656 TI - Shock as a complication of the nephrotic syndrome. PMID- 4289657 TI - Cytomegalic inclusion disease. PMID- 4289658 TI - An evaluation of the lipiodol test for the detection of steatorrhoea. PMID- 4289659 TI - Polymyalgia rheumatica. A rheumatic disease of the elderly. PMID- 4289660 TI - Effects of ionizing radiation on two gelatin fractions. 3. Carbonyl group analyses and electron spin resonance studies. PMID- 4289661 TI - Effect of glidants in tableting. PMID- 4289662 TI - Effect of vasopressor substances on the thoracic duct lymph flow. PMID- 4289663 TI - Radiographic findings in hypothalamic acceleration of growth associated with cerebral atrophy and mental retardation (cerebral gigantism). PMID- 4289664 TI - A simple, practical technic of lymphography. PMID- 4289665 TI - Acute respiratory illness with Mycoplasma pneumoniae. An outbreak in a home for children. PMID- 4289667 TI - Multiple granular cell myoblastoma. PMID- 4289666 TI - Prophylactic antibiotics and postoperative endophthalmitis. PMID- 4289668 TI - [Studies on the behavior of the serum glucose-6-phosphatase activity in acute hepatitis]. PMID- 4289669 TI - Human leukemia virus in mice. PMID- 4289670 TI - The use of gel filtration to distinguish between endonucleolytic and exonucleolytic types of degradation. PMID- 4289671 TI - The natural occurrence of a uracil-5-peptide and its metabolic relationship to guanosine-5'-monophosphate. PMID- 4289672 TI - Isolation of Sendai virus RNA from infected cells by the method of thermic fractionation. PMID- 4289673 TI - The polysomes and the messenger ribonucleic acid content of hepatoma 223. PMID- 4289674 TI - [Endocrinological test of the pituitary-adrenal cortex system]. PMID- 4289675 TI - [Adenoviruses and their role in human pathology]. PMID- 4289676 TI - [Studies on the retinal blood pressure in cats under various conditions]. PMID- 4289677 TI - Respiratory illness and viral infection in an Edinburgh nursery. PMID- 4289678 TI - Experimental infection of common terns with Tern virus: influenza virus A-Tern South Africa-1961. PMID- 4289679 TI - Genetic marker studies of poliovirus. I. Natural variation. PMID- 4289680 TI - Genetic marker studies of poliovirus. II. Strains isolated from cases of poliomyelitis associated with the administration of live attenuated vaccine. PMID- 4289681 TI - Intermittent hemodialysis for chronic renal failure. PMID- 4289682 TI - Ultrastructural alterations of hepatic microbodies. PMID- 4289683 TI - Electron microscopic observations on Herpesvirus hominis (herpes simplex virus) encephalitis in man. PMID- 4289684 TI - Effect of nitrous acid on polyoma virus. PMID- 4289685 TI - Electron spin resonance study of thermal effects in irradiated deoxyribonucleic acid. PMID- 4289686 TI - [Comments on the Pharmacopeia Nordica, Vol. IV. Commentary on the change of corticotropin methods]. PMID- 4289687 TI - Angiography in primary hepatic carcinoma. PMID- 4289688 TI - Treatment of parotid tumors. PMID- 4289689 TI - The relationship between dental and skeletal maturation in Chinese children. PMID- 4289690 TI - Antirachitic sterols in chicks. Rachitic bone lesions in chicks after multiple graded doses of vitamin D and dihydrotachysterols. PMID- 4289691 TI - Iron-loading, fibrosis, and hepatic carcinogenesis. PMID- 4289692 TI - A re-evaluation of the place of major extirpation in the management of patients with metastatic mammary carcinoma. AB - Clearly defined indications for major extirpation procedures in metastatic mammary carcinoma are lacking. A reassessment of experience with 222 patients (133 after adrenalectomies and 89 after hypophysectomies) was therefore undertaken. This experience has changed our previous opinions that such procedures should be used only at the end of a sequential program of treatment.It is now felt that extirpation is only contraindicated in menopausal women with a duration of disease less than two years or when there is symptomatic disease of vital organs. Otherwise, early extirpation is recommended. When vital organ involvement is recognized in the asymptomatic stage or when screening of premenopausal women by castration indicates continuing hormonal dependency, then early extirpation is indicated.Both the qualitative and the quantitative responses achieved exceed those obtained by other measures when widely disseminated disease is present. The objective remission rate (34% after adrenalectomy and 19% after hypophysectomy) for longer than six months is worth while. PMID- 4289693 TI - Peripheral neuropathy with sympathetic overactivity from industrial contact with acrylamide. AB - This paper describes the experimental and clinical findings of acrylamide intoxication in a human being. It is believed that this is the first such case to be recorded in the medical literature.Acrylamide is widely used as a "chemical grout". It is pumped into dirt, clay and stone walls of excavations in a liquid state together with a catalyst, and it then polymerizes to make a watertight shield.This chemical is neurotoxic in its non-polymerized form and can be absorbed through the intact skin, mucous membranes and lungs. In spite of warnings with regard to its handling, this worker became careless, and developed a contact dermatitis and a polyneuropathy with bluish cold extremities which dripped perspiration.In six months' time after his removal from contact with the chemical the patient made a complete clinical recovery. He was advised not to work with the chemical. PMID- 4289694 TI - Effects of mammalian hypophysial hormones, placentral gonadotrophins, gonadal hormones, and adrenal corticosteroids on ovulation and spawning in hypophysectomized catfish, Heteropneustes fossilis (Bloch). PMID- 4289695 TI - Erythropoietin-producing Wilms' tumor. PMID- 4289696 TI - Relation of cardiac work to survival in cardiogenic shock in dogs. PMID- 4289697 TI - [Value of intratype serum differentiating reaction in type 3 poliovirus identification]. PMID- 4289698 TI - Absence attacks and diffuse neuronal disease. PMID- 4289699 TI - [Clostridium perfringens septicemia with symptoms of meningitis after perineal trauma]. PMID- 4289700 TI - [New operative method for syndactylia with special reference to syndactylia of 3 fingers]. PMID- 4289701 TI - Electron spin resonance studies of free radical turnover in gamma-irradiated single crystals of alanine. PMID- 4289702 TI - [Arrhenoblastoma in 2 sisters]. PMID- 4289703 TI - Changes in glutamic-alanine transaminase activity in response to corticoid treatment in hepatoma and the precancerous liver of rats induced by 3'-methyl-4 dimethyl amino-azo benzene. PMID- 4289704 TI - The adrenal response to surgical trauma. PMID- 4289705 TI - Surgical methods in syndactylism. Evaluation of 208 operations. PMID- 4289706 TI - [Research on complement fixing antibodies against adenovirus in the nursing personnel of a hospital complex]. PMID- 4289707 TI - [On the diffusion of complement fixing antibodies against adenoviruses in subjects living in a closed community. Research before and after the winter season]. PMID- 4289708 TI - [Experimental research on the humoral and tissue changes capable of conditioning neoplastic progression. II]. PMID- 4289709 TI - Histochemical observations on Posthodiplostomum minimum. 3. Alkaline phosphatase activity in metacercariae and adults. PMID- 4289710 TI - Immunogenicity of synthetic angiotensin II. PMID- 4289711 TI - Fixation of topically applied fluoride in enamel. PMID- 4289712 TI - The value of corticosteroids in the treatment of infectious mononucleosis. PMID- 4289713 TI - Suppression of interferon and antibody and multiplication of Newcastle disease virus in cytomegalovirus infected mice. PMID- 4289714 TI - Effect of hyperbaric oxygen on Clostridia in vitro and in vivo. PMID- 4289715 TI - Attachment of modified erythrocytes to phagocytic cells in absence of serum. PMID- 4289716 TI - Amino acid composition of three immunological types of foot-and-mouth disease virus. PMID- 4289717 TI - In vitro production and inhibition of aortic vasoconstriction by mercuric, cadmium, and other metal ions. PMID- 4289718 TI - Serotonin-bradykinin synergism in the mammalian capillary bed. PMID- 4289719 TI - A study of teratogenic effects of particulate compounds in the amniotic cavity of chick embryos. PMID- 4289720 TI - Lack of effect of alpha-ethyltryptamine on ACTH secretion when blood pressure is held constant. PMID- 4289721 TI - Effect of temperature and drug therapy on anthrax intoxication. PMID- 4289722 TI - Evaluation of arteriography in obstetrics. PMID- 4289723 TI - Femoral neuropathy from the lithotomy position: case report and new leg holder for prevention. PMID- 4289724 TI - Effect of sewage treatment on recovery of poliovirus following mass oral immunization. PMID- 4289725 TI - Plasma angiotensinase activity in hypertensive patients. PMID- 4289726 TI - EPR measurements of substrate interaction with cytochrome P-450. PMID- 4289727 TI - The role of metal ions in the gamma-radiolysis of dry metal-ribonuclease complexes. PMID- 4289728 TI - Rat liver and hepatoma polysome-membrane interaction in vitro. PMID- 4289729 TI - The effects of adenine nucleotides on pig heart malate dehydrogenase. PMID- 4289730 TI - Vitamin D mediated synthesis of rapidly labeled RNA from intestinal mucosa. PMID- 4289731 TI - Differential consumption of coagulation factors resulting from activation of the extrinsic (tissue thromboplastin) or the intrinsic (foreign surface contact) pathways. PMID- 4289732 TI - The isolation of herpes virus from Burkitt tumours. PMID- 4289733 TI - The isolation in mice of strains of herpes virus from Burkitt tumours. PMID- 4289734 TI - Studies on the anti-tumour activity of aliphatic aldehydes. II. Effects on survival of Yoshida ascites hepatoma-bearing rats. PMID- 4289735 TI - Changes with age in fragmentation of cellular nucleus DNA. PMID- 4289736 TI - Diagnosis and treatment of skin tumors in the AGED. PMID- 4289737 TI - Eosinophilic granuloma of the gastro-intestinal tract. PMID- 4289738 TI - Ontogeny of macrophage resistance to mouse hepatitis in vivo and in vitro. AB - Adult or weanling C(3)H mice were found to be genetically resistant to a strain of mouse hepatitis virus. Infant C(3)H mice, however, developed infection and died from mouse hepatitis virus when minimal infectious doses of virus were given to them. There was a delay in the time of death compared to that of the genetically susceptible strain, and the virus recovered from these mice had increased pathogenicity for C(3)H mice. The ontogeny of resistance to hepatitis in the C(3)H mice thus progresses from delayed susceptibility to complete resistance as the age of the host increases. It is reflected in increased resistance of macrophages derived in vitro from liver cultures of infant mice of different ages. This increase in resistance with age was reduced by maintaining the cultures for a longer period of time before inoculation, or by increasing the number of explants in a given culture. Resistant cells were uniformly furnished by mice age 16 days, or more. It is concluded that a process of maturation of resistance of the cells takes place after the mice are born, but that this does not continue under in vitro conditions, and that it may be modified by the environment of the cells. PMID- 4289739 TI - Demonstration by immunofluorescence of the fixation of perfused antibody to human collagen in human kidney. AB - Rabbit serum containing antibody to human collagen, perfused through human infant kidneys obtained at autopsy, gives an immunofluorescent reaction with an antigen in the basement membranes of the glomeruli and the tubules. This reaction was shown to be specific by the absence of reaction with normal rabbit serum, antibody to carp collagen, or anti-human collagen serum absorbed with human collagen. Slight cross-reactions were found in the human kidneys with antibody to chicken or rat collagen. There was no evidence that a collagen-like protein in human serum or an antigen common to human erythrocytes and renal glomeruli enters into this immunofluorescent reaction. Perfusion of the kidneys with purified collagenase before the introduction of the antibody to human collagen altered the antigen so that antibody could not be demonstrated in the basement membranes by immunofluorescence. Testicular hyaluronidase used in the same way did not affect the immunofluorescent reaction. This method of perfusion provides another means for studying antigens in human organs by immunofluorescence. These observations in human kidneys extend our earlier findings in laboratory animals and indicate that an antigen, collagen, is also present in human renal glomerular and tubular basement membranes. PMID- 4289740 TI - Studies on the leukocytosis and lymphocytosis induced by Bordetella pertussis. II. The effect of pertussis vaccine on the thoracic duct lymph and lymphocytes of mice. AB - The 24 hr volume flow, cell concentration, and total cell output of thoracic duct fluid from mice with pertussis-induced hyperlymphocytosis were markedly reduced when compared with values obtained in normal animals. An increase in the number of circulating lymphocytes occurred in several of the pertussis-treated mice despite the presence of an indwelling thoracic duct cannula. The drainage from such animals also showed a reduced cell concentration and total cell output. It is suggested that lymphocyte recirculation may be minimal in pertussis-induced lymphocytosis, and the evidence obtained also suggests that lymphocytes may enter the blood stream by direct routes during the course of the reaction. PMID- 4289741 TI - In vitro transformation by the adenovirus-SV40 hybrid viruses. II. Characteristics of the transformation of hamster cells by the adeno 2-, adeno 3-, and adeno 12-SV40 viruses. AB - Primary weanling hamster kidney cultures were transformed with the adeno 2-SV40, adeno 3-SV40, and adeno 12-SV40 hybrid viruses and with adenovirus type 12. The transformed cell lines which were established were characterized with respect to morphology, virus and antigen content, and chromosome aberrations. The adeno 2 and adeno 3-SV40 hybrid transformed cells had the morphology and T antigen content characteristic of SV40 transformations; cells transformed by the former hybrid had cytogenetic changes typical of SV40-transformed cells as well. The adeno 12-SV40 transformed cells were similar morphologically to adeno 12 transformed cells, contained both the SV40 and adeno T antigens and demonstrated the karyotypic instability of SV40-transformed cells, indicating that both viral genomes are operative in these cells. Although the results indicate that the SV40 genome in hybrids derived from the moderately or nononcogenic adenoviruses supplies the determinants for most of the characteristics investigated, and perhaps for oncogenesis, evidence was presented which suggests that a portion of a nononcogenic adenovirus genome may be integrated in adeno 2-SV40 transformed cells and directs the synthesis of adenovirus T antigens. PMID- 4289742 TI - In vitro transformation by the adenovirus-SV40 hybrid viruses. 3. Morphology of tumors induced with transformed cells. AB - Tumors induced with hamster kidney cells transformed by the adeno 2-, adeno 3-, adeno 7-, and adeno 12-SV40 hybrid viruses, and by adenovirus type 12, were examined histologically. The tumors induced with adeno 2-, adeno 3-, and adeno 7 SV40-transformed cells were similar to tumors induced with SV40-transformed hamster kidney cells but contained cells intermediate in morphology between SV40 and adenovirus tumor cells and occasionally contained nests of adenovirus-like cells. Cells transformed by the adeno 12-SV40 hybrid and by adenovirus type 12 gave rise to morphologically similar tumors. The results suggest that both viral genomes are operative in hybrid-transformed cells but that one genome is apparently responsible for the predominant morphology of the tumor. Evidence that the morphology of a single transformed target cell is determined by the transforming genome was discussed. PMID- 4289743 TI - Locally advanced lung carcinoma with favorable prognosis. PMID- 4289744 TI - [Cerebral phosphoprotein phosphatase]. PMID- 4289745 TI - [Mixed tumor starting from the jaw bone]. PMID- 4289746 TI - Virus particles and murine leukemia virus complement-fixing antigen in neoplastic and nonneoplastic cell lines. AB - Twenty-seven lines of murine tissue cultures derived from 12 different cell pools and grown on various media were examined with the electron microscope for morphologically detectable virus particles. They were also tested for complement fixing mouse leukemia virus antigens and for recoverable virus. A 100-percent correlation between results obtained by these two methods is reported. An additional 19 lines from 8 different cell pools were examined for either virus particles or complement-fixing antigens. All lines were assayed for neoplastic transformation. Seven cell pools gave rise to lines showing evidence of contamination with leukemia virus. Since most of these lines had also undergone "spontaneous" neoplastic transformation in vitro, this virus cannot be excluded as a possible cause of the neoplastic change, or of influencing it. The remaining cell pools gave rise to lines with no evidence of contamination with leukemia virus;but most of these lines also underwent similar transformation. These results suggest that "spontaneous" neoplastic transformation can occur in the absence of detectable mouse leukemia virus. PMID- 4289747 TI - [The treatment with ACTH of postoperative local reactions in bucco-maxillo-facial surgery]. PMID- 4289748 TI - The management of keratoconjuctivitis sicca. PMID- 4289749 TI - Interpretation of fundus signs in angioid streaks. PMID- 4289750 TI - Thermal and chemical burns of the head and neck. PMID- 4289751 TI - Respiratory syncytial virus. An outbreak of acute respiratory illnesses in a home for infants. PMID- 4289752 TI - Experimental observations on intraportal inoculation with E. histolytica. PMID- 4289753 TI - Pyridine nucleotides. I. Radiometric determination of minute quantities of diphosphopyridine nucleotides. PMID- 4289754 TI - Studies on the ultraviolet fluorescence of vitamin D and related compounds in acid-alcohol solutions. PMID- 4289755 TI - Methods for the analysis and preparation of adenosylmethionine and adenosylhomocysteine. PMID- 4289756 TI - Neural injury resulting from epidural injection of dimethylsulfoxide and procaine base. PMID- 4289757 TI - Electron paramagnetic resonance studies on the ferredoxin from Clostridium pasteurianum. PMID- 4289758 TI - Identification of the nucleoside monophosphate end-group on the product of the polynucleotide phosphorylase reaction. PMID- 4289759 TI - Perillyl alcohol dehydrogenase from a soil pseudomonad. PMID- 4289760 TI - The solvent denaturation of double-stranded RNA from poliovirus infected HeLa cells. PMID- 4289761 TI - Electron spin resonance studies of ferrihaemoglobin MOsaka. PMID- 4289762 TI - Nicotinamide-adenine dinucleotide dehydrogenase activity of human erythrocyte membranes. PMID- 4289763 TI - Carbamylphosphate, a preferential substrate of K+-dependent phosphatase. PMID- 4289764 TI - Role of norepinephrine and 5-hydroxytryptamine in the delayed phase of the inflammatory reaction in rats. PMID- 4289765 TI - Pyrimidine dimers in ultraviolet-irradiated DNA's. PMID- 4289766 TI - Clinical choriomatosis. PMID- 4289767 TI - The follow up of hydatidiform mole. PMID- 4289768 TI - Gonadotrophin excretion, pelvic arteriography and treatment in post-molar trophoblastic disease. PMID- 4289769 TI - The diagnosis of insuloma. PMID- 4289770 TI - Histochemical examinations in mucosal tongue atrophy. PMID- 4289771 TI - Percutaneous transhepatic cholangiography. PMID- 4289772 TI - Carcinoma of the floor of the mouth. Review of clinical factors and results of treatment. PMID- 4289773 TI - Cancer of the nasopharynx: 142 patients treated in the 11 year period 1950-1960. PMID- 4289774 TI - Therapy of lymphangiosarcoma of the chronically edematous limb. Five-year cure of a patient treated by intra-arterial radioactive yttrium. PMID- 4289775 TI - Radiation therapy of sarcoma of the bone and soft tissue. PMID- 4289776 TI - Colloidal thorium dioxide (thorotrast) in radiology with emphasis on hepatic cancerogenesis. A case report of occluded carotid and jugular vessels with nerve injuries and a case of hepatoma, 27 and 33 years after its administration. PMID- 4289777 TI - Immunochemical studies on blood groups. XXXIV. Structures of some oligosaccharides produced by alkaline degradation of blood group A, B, and H substances. PMID- 4289778 TI - The catalytic properties of tyrosyl ribonucleic acid synthetases from Escherichia coli and Bacillus subtilis. PMID- 4289779 TI - Effect of neutral salts on enzyme activity and structure. PMID- 4289780 TI - Use of antibodies to sera of hypophysectomized animals in pituitary hormone analysis and the application of Landsteiner's inhibition test in agar gel immunoassays. PMID- 4289781 TI - Incorporation in vitro of precursor into protein and RNA of rat adrenal glands. PMID- 4289782 TI - [Research on vascular diseases in aged persons with thyroid pathology]. PMID- 4289783 TI - An extra-adrenal effect of corticotrophin. PMID- 4289784 TI - Test for corticotrophin-producing function of pituitary using vasopressin. PMID- 4289785 TI - Mixed anaerobic infection in minor trauma. PMID- 4289786 TI - The effect of synthetic angiotensin-II-amide and methopyrapone (SU 4885) on the histochemistry of the adrenal cortex of intact and hypophysectomized rats. PMID- 4289787 TI - Experiences in treating excessive height in girls with cyclic oestradiol valerate. A ten year survey. PMID- 4289788 TI - Steroid hormone formation by the rat ovary. IV. Formation of steroids from acetate-1-14C by neoplastic ovarian tissue. PMID- 4289789 TI - Isolation of an adenovirus from the brain of a pig. PMID- 4289790 TI - [On the optical determination of citrate synthase and acetyl-coenzyme A]. PMID- 4289791 TI - [On the determination of a RNA polymerase activity in mitochondria of animal cells]. PMID- 4289792 TI - [Acylphosphate: D-glucose-6-phosphotransferase]. PMID- 4289793 TI - [Application of electron spin resonance in radiation biology]. PMID- 4289794 TI - Soft-tissue calcification induced by rare earth metals and its prevention by sodium pyrophosphate. PMID- 4289795 TI - Studies on latent derivatives of aminoethanethiols as potentially selective cutoprotectants. IV. Enzymatic hydrolysis of cysteamine-S-phosphate. PMID- 4289796 TI - Ultrastructural changes produced by triparanol in Morris 5123 and Novikoff hepatomas. PMID- 4289797 TI - Carcinogenesis in AKR mice injected at birth with benzo(a)pyrene and dimethylnitrosamine. PMID- 4289798 TI - The oxidation of extramitochondrial reduced diphosphopyridine nucleotide in ascites tumor cells. PMID- 4289799 TI - Effects of adrenocorticotropic hormone and growth hormone on the metabolism of N hydroxy-N-2-fluorenylacetamide and on physiologic parameters. PMID- 4289800 TI - Screening data from the Cancer Chemotherapy National Service Center screening laboratories. XL. Plant extracts. PMID- 4289801 TI - Uptake and scanning of the salivary glands in man using pertechnetate-99m-Tc. PMID- 4289802 TI - Clinical neuropathological conference. PMID- 4289803 TI - Histochemical localization of gastric and small bowel mucosal enzymes of man, monkey, and chimpanzee. PMID- 4289804 TI - The abolition of the protective effect of Clostridium welchii type A antiserum by ferric iron. PMID- 4289805 TI - Serological activity of staphylococcal polysaccharide. AB - The polysaccharide from cell walls of coagulase-positive staphylococci coated both latex particles and tanned red cells for agglutination by human sera and by specific staphylococcal antisera. Treatment with trypsin or autoclaving destroyed the capacity of polysaccharide to coat particles but did not affect precipitation of antibody. Periodic acid destroyed both properties. The teichoic acid portion of the staphylococcal polysaccharide displayed precipitin activity similar to polysaccharide, but it did not coat either latex particles or tanned red cells. Teichoic acid did, however, inhibit specific agglutination of polysaccharide coated particles or cells. PMID- 4289806 TI - Adenosine phosphate hydrolases in cell fractions of Vitreoscilla. AB - Bound, soluble, and whole-cell fractions of two strains of the gliding bacterium Vitreoscilla were found to contain two enzymes capable of hydrolyzing adenosine phosphates: a Mg(++)-activated adenosine triphosphatase with a temperature optimum of 37 C, and a Mg(++)-activated adenosine diphosphatase with a temperature optimum of 55 C. Both enzymes had an optimal pH response between 8.5 and 9.5. Maximal activation was achieved at an ionic strength of 0.2 for the adenosine triphosphatase and at 0.3 to 0.4 for the adenosine diphosphatase. Preliminary studies indicated a molecular weight of approximately 50,000 for the adenosine diphosphatase and a molecular weight greater than 60,000 for the adenosine triphosphatase. Comparisons are made with previously reported characteristics of these enzymes in other bacteria, and a hypothesis is offered as to the role these enzymes have in the gliding mechanism. PMID- 4289807 TI - Bacterial metabolism of mevalonic acid. AB - Soluble cell-free extracts of actinomycete S4 grown on media containing mevalonate catalyze acetoacetate formation from mevalonate, mevaldate, and beta hydroxy-beta-methylglutaryl-coenzyme A (CoA). Conversion of mevalonate to acetoacetate involves formation of free beta-hydroxy-beta-methylglutaryl-CoA, but not free mevaldate. The reaction favors mevalonate oxidation, and nicotinamide adenine dinucleotide, rather than nicotinamide adenine dinucleotide phosphate, acts as oxidant. PMID- 4289808 TI - Spectrophotometric and kinetic study of nitrite and formate oxidation in Nitrobacter winogradskyi. AB - The reduction levels of cytochrome c and a(1) in intact Nitrobacter cells and cell-free extracts, during and after nitrite or formate oxidation, were examined in combination with the amperometric measurement of oxygen uptake. Quite different reduction patterns were observed when comparing nitrite oxidation by intact cells and cell-free extracts. An inverse relationship was observed between the rate of electron flow and the steady-state reduction level of cytochrome a(1). Parallel observations on nitrite oxidation, by use of formate and reduced nicotinamide adenine dinucleotide as electron donors, showed the influence of the high oxidation-reduction potential of the nitrite-nitrate system on cytochrome reduction. A value for the apparent activation energy of the overall nitrite oxidation process, amounting to 15 kcal, was found in a study of the temperature dependence of cytochrome reduction. PMID- 4289809 TI - Some properties of heat-resistant and heat-sensitive strains of Clostridium perfringens. I. Heat resistance and toxigenicity. AB - Heat resistance at 100 C (D-values), sporulating ratios, toxigenicity for mice, and lecithinase activity (as micrograms per milliliter of enzyme, ascertained by the lecithovitellin reaction) were determined for four strains of Clostridium perfringens. A definite inverse relationship between thermal resistance and toxigenicity was found. The D-values ranged from 17.6 for the most heat-resistant strain to 0.3 for the strain possessing the least heat resistance, with corresponding lecithinase activities from 25 to 133 mug/ml of enzyme. The sporulating ratios did not differ greatly between the strains. The heat stability of the toxin was greater at 100 C than at 75 C. There was a noticeable difference between the heat stabilities of the toxin in the culture fluids of the heat sensitive and heat-resistant strains at pH 7.0 when the toxic filtrates were held at 100 C. At a holding temperature of 75 C, a similar but lesser difference was observed at pH 5.5. Heat resistance and lecithinase activity did not change when a substrain of the least heat-resistant parent strain was obtained through heat selection by a single transfer, or when the most heat-resistant strain was transferred serially 12 times. PMID- 4289810 TI - Effects of oxygen and heme on the development of a microbial respiratory system. AB - The effect of adding hemin to anaerobically grown cells of a strain of Staphylococcus epidermidis, which was heme-deficient due to anaerobic growth, has been examined. Cells grown anaerobically in media containing hemin exhibited a marked increase in several oxidative activities as compared with cells grown anaerobically without hemin. The respiratory activity of whole cells and a cyamide-sensitive reduced nicotinamide adenine dinucleotide oxidase activity of cell-free extracts were increased fourfold. The content of enzymatically reducible pigments which exhibit difference spectra similar to cytochromes b(1) and o was also markedly increased. These pigments are mostly sedimented at 100,000 x g (1 hr). Hemin also caused a marked increase in respiratory activity when added directly to the anaerobic culture after the period of growth, but did not cause a similar increase in respiration when added to washed, resting-cell suspensions. Under the latter conditions, heme pigments were formed which exhibited difference spectra similar to, but not identical with, the spectra of pigments found in anaerobic cells grown in the presence of hemin. When resting suspensions of cells grown anaerobically without hemin were exposed to air, a rapid fourfold increase in respiratory activity and a limited increase in cytochrome-like pigments occurred. The presence of the heme precursor Delta aminolevulinic acid during this aeration resulted in a rapid and marked increase in heme pigments, but only a slight stimulation of respiratory activity. The possible implications of these results for the roles which heme and oxygen play in the development of the respiratory system of this organism are discussed. PMID- 4289811 TI - Metabolic changes in nicotinamide adenine dinucleotide in response to anthrax toxin. AB - Bacillus anthracis produces a toxin both in vitro and in vivo which, when injected intravenously into rats, brings about the death of the animals accompanied by gross pulmonary edema. Lung tissue removed prior to death showed, in vitro, a 30% reduction in overall oxidative metabolism (Q(o2)), whereas the nicotinamide adenine dinucleotide (NAD)-independent succinic dehydrogenase remained unaffected. The NAD concentration in the lungs of injected animals was reduced by 50%. Upon addition of NAD, the Q(o2) of lung tissue from injected animals rose to control values. At 45 min after toxin injection, the serum lactate concentration began to rise, showing about a 3.5-fold increase over controls after 75 min. No changes occurred in the pyruvate concentration. These changes may be explained by increased use of the pyruvate for glycolytic energy production with further loss of NAD. Additional experiments with liver, spleen, kidney, and brain tissues showed that the toxin-induced reduction of Q(o2) is an effect specific for lung tissue. Brain tissue showed a significant increase in oxidative metabolism upon the addition of the toxin, whereas the other tissues remained unaffected. It is suggested that a principal effect of the toxin is to inhibit, in lung tissue, the regeneration of NAD in the respiratory chain. PMID- 4289812 TI - The state of copper in Rhus laccase as compared with those in other copper complexes. PMID- 4289813 TI - On the purification and properties of mushroom tyrosinase. PMID- 4289814 TI - Studies on cell walls of Mycobacteria. II. Constitution of polysaccharides from BCG cell walls. PMID- 4289815 TI - The oxidation of protein-bound hydroxylysine by periodate. PMID- 4289816 TI - Studies on cytochrome oxidase. 3. Ligand reactions and Schiff base formation of heme a. PMID- 4289817 TI - Nicotinamide adenine dinucleotide as a precursor of nicotine in Nicotiana rustica L. PMID- 4289818 TI - Heme A of cytochrome c oxidase. I. Isolation from bovine heart. PMID- 4289819 TI - The enzymatic cleavage of phosphate termini from polynucleotides. PMID- 4289820 TI - Isolation and structure of cytidine diphosphate 6-deoxy-3-C-methyl-2-O-methyl-L aldohexopyranoside (cytidine diphosphate vinelose) from Azotobacter vinelandii. PMID- 4289821 TI - Structure and distribution of a disaccharide-carrying nucleotide and related nucleotides in hen oviduct. PMID- 4289822 TI - Virus-like particles in established murine cell lines: electron-microscopic observations. AB - Virus-like particles identical in morphology to the RNA tumor vi ruses have been observed by electron microscopy in six lines of murine L cells and one line of murine liver cells. Control cultures of embryonic mouse cells and 3T3 cells do not contain the particles, and no biologic activity has as yet been associated with them. PMID- 4289823 TI - Mixed tumors of minor salivary glands. PMID- 4289824 TI - Severe spinal curvature in rats injected with a water-dispersible vitamin D3 preparation. PMID- 4289825 TI - Localization of avian tumor virus group-specific antigen in cell and virus. PMID- 4289826 TI - Metabolic requirements for infection by Rous sarcoma virus. II. The participation of cellular DNA. PMID- 4289827 TI - Origin of group-specific antigen of chicken leukosis viruses. PMID- 4289828 TI - The loss of photosensitivity of proflavine-sensitized encephalomyocarditis virus on contact with nonsusceptible cells. PMID- 4289829 TI - Circulatory changes following angiotensin administration. PMID- 4289830 TI - Rabbit uterus as a source of renin. PMID- 4289831 TI - Absorption and electrolyte changes of intestinal mucosa following substrate induction. PMID- 4289832 TI - Alkylation of cytochromes c. I. Properties of alkylated beef cytochrome c. PMID- 4289833 TI - The effect of coenzyme on the S--N acyl migration in glyceraldehyde-3-phosphate dehydrogenase. PMID- 4289834 TI - The oxidation of gentisaldehyde by nicotinamide-adenine dinucleotide-specific, aromatic aldehyde dehydrogenase from rabbit liver. PMID- 4289835 TI - Enzymes of glycogen metabolism in white blood cells. II. Activation and inactivation of glycogen phosphorylase of rat chloroma. PMID- 4289836 TI - Enzymes of glycogen metabolism in white blood cells. 3. Heterogeneity of glycogen phosphorylase from rat chloroma. PMID- 4289837 TI - The determination of the oxidation-reduction states of ubiquinone (coenzyme Q) in rat-liver mitochondria. PMID- 4289838 TI - Electron transfer between ferro- and ferricytochrome c. PMID- 4289839 TI - Purification and properties of cytochrome a of Candida krusei. PMID- 4289840 TI - The effect of heat on the structure of foot-and-mouth disease virus and the viral ribonucleic acid. PMID- 4289841 TI - Interference of actinomycin D with the replication of the herpes virus DNA. I. Difference in behaviour of cellular and viral nucleic acid synthesis following treatment with actinomycin D. PMID- 4289842 TI - Interference of actinomycin D with the replication of the DNA of herpes virus. II. Relationship between yield of virus and time of actinomycin treatment. PMID- 4289843 TI - The roles of three enzymes in messenger RNA degradation in cell-free systems from normal or phage-infected Escherichia coli. PMID- 4289844 TI - Enzymic conversion of thymidine 3'-monophosphate to thymidine 3'-diphosphate and 3'-triphosphate. PMID- 4289845 TI - Experimental studies on the bacteriocinogeneity in Cl. perfringens type A. II. Properties of isolated bacteriocines. PMID- 4289846 TI - The chemistry of the polymyxin antibiotics. PMID- 4289847 TI - Chemical structure of polymyxin D1. PMID- 4289848 TI - In vivo assay for melanocyte lightening substances. PMID- 4289849 TI - Effects of angiotensin on the superior cervical ganglion of the cat. PMID- 4289850 TI - Mechanisms of pathogenesis in Listeria monocytogenes infection. 3. Carbohydrate metabolism. AB - Several enzymes and metabolites concerned with carbohydrate metabolism were examined in mice infected with Listeria monocytogenes. Liver glycogen and glucose decreased parallel to severity of infection. The concentration of glucose in the blood fell to abnormally low levels with a hypoglycemia being most evident at 72 hr. There was a significant decrease in the activity of hepatic uridine diphosphate glucose-glycogen transglucosylase. This decrease in enzymatic activity correlated with the rate of glycogen depletion. Phosphorylase activity declined in a similar fashion, contraindicating enhanced glycogenolysis as the mechanism responsible for glycogen depletion. Although glucose-6-phosphatase decreased throughout the infection period, it did not appear to be the major metabolic defect causing hypoglycemia in Listeria-infected mice. Further distortion of carbohydrate metabolism was indicated by findings of increased levels of pyruvate and lactate in the blood of infected animals. PMID- 4289851 TI - Effect of glucose on the formation of the membrane-bound electron transport system in Haemophilus parainfluenzae. AB - The catabolism of glucose by Haemophilus parainfluenzae affected the formation of the primary dehydrogenases of the membrane-bound electron transport system. The formation of other components of the respiratory system, 2-demethyl vitamin K(2), cytochrome b(1), cytochrome c(1), and the cytochrome oxidases a(1), a(2), and o, is not affected by the catabolism of glucose. The formation of all components of the electron transport system is controlled by the identity and concentration of the terminal electron acceptors present in the growth medium. PMID- 4289852 TI - The terpene-producing glands of a Phasmid insect. Cell morphology and histochemistry. PMID- 4289854 TI - Goblet cells in an apical periodontal cyst. Report of a case. PMID- 4289853 TI - Myocardial "protective effect" of 5-OH tryptamine during tryptophan deficiency. PMID- 4289855 TI - Attempt at dynamic investigation of bioactivity of adrenal cortical zones after corticotrophine in the excreted urine of patients with articular disease. PMID- 4289856 TI - Isolation of a bovine enterovirus. PMID- 4289857 TI - Quantitative determination of chrysotile, amosite and crocidolite by x-ray diffraction. PMID- 4289858 TI - Renewed interest in gases for contrast roentgenography. PMID- 4289859 TI - A comparative study of roentgenographic techniques for detection of calcium pyrophosphate dihydrate deposits (pseudogout) in human cartilage. PMID- 4289860 TI - A kinetic study of ternary complexes in the mechanism of action of liver alcohol dehydrogenase. PMID- 4289861 TI - Fluorescence enhancement of uridine diphosphagalactose 4-epimerase induced by specific sugars. PMID- 4289862 TI - The mitochondrial electron transfer chain. PMID- 4289863 TI - The interrelationship between guanosine triphosphatase and amino acid polymerization. PMID- 4289864 TI - Reversible inactivation of D-fructose 1,6-diphosphatase by adenosine triphosphate and cyclic 3' ,5'-adenosine monophosphate. PMID- 4289865 TI - [Studies on the propagation of the virus of infectious bovine rhinotracheitis (IBR) and vesicular eruption of cattle (IPV) in calf kidney monolayer cell cultures]. PMID- 4289866 TI - Inorganic pyrophosphate in parotid saliva and its relation to calculus formation. PMID- 4289867 TI - Mixed salivary tumour of the nasal septum. Case report. PMID- 4289868 TI - Studies on the mechanism of action of glyceraldehyde 3-phosphate dehydrogenase. Absorbance and fluorescence properties of reduced nicotinamide-adenine dinucleotide complexes with glyceraldehyde 3-phosphate dehydrogenase. PMID- 4289869 TI - Fructose 1,6-diphosphatase from rabbit liver. VI. Functional tyrosyl residues in the active center. PMID- 4289870 TI - The clinical application of a gas chromatographic method for the routine determination of urinary pregnanediol. PMID- 4289871 TI - Studies on 17-ketosteroids in juvenile diabetes mellitus. PMID- 4289872 TI - Effect of ACTH on open-field behavior, avoidance, startle, and food and water consumption. PMID- 4289873 TI - The microbiological diagnostics of strains of Aeromonas shigelloides isolated in Cuba. PMID- 4289874 TI - Hemodynamically induced natriuresis in the presence of sodium retention resulting from constriction of the thoracic inferior vena cava. PMID- 4289875 TI - Oxidative phosphorylation and respiratory control of brain mitochondria isolated from kernicteric rats. PMID- 4289876 TI - The presence of distinct soluble and particulate trypsin inhibitors in human astrocytoma tissue. PMID- 4289877 TI - Ultrastructural and enzymic studies of cholinergic and non-cholinergic synaptic membranes isolated from brain cortex. PMID- 4289878 TI - The phospholipid composition of the cerebrospinal fluid in children with mental deterioration. PMID- 4289879 TI - Adrenocorticotrophic hormone and platelet stickiness. PMID- 4289880 TI - Metabolic pathways of the host cell important in the replication of Rous sarcoma virus in vitro. PMID- 4289881 TI - Subcellular distribution of catecholamines in dog spleen. PMID- 4289882 TI - The prevalence of diabetes mellitus in patients with Addison's disease: measurements of serum insulin levels. PMID- 4289883 TI - Effect of drugs on the lipolytic action of hormones in isolated fat cells. PMID- 4289884 TI - [On a cylindromatous formation of the palate]. PMID- 4289885 TI - Manganese free radicals in cobalt-60 gamma-irradiated strawberries. PMID- 4289886 TI - Reduced diphosphopyridine nucleotide-dependent diaphorase in foetal, newborn and adult cattle. PMID- 4289887 TI - Functional and analytical histochemistry of the chicken lung lobule with particular reference to surfactant. PMID- 4289888 TI - Neutralizing ability of sera from three strains of chickens for Rous sarcoma virus. PMID- 4289889 TI - Studies on the inhibition of polyoma virus replication in vitro: comparison of the effects of phenethyl alcohol, 5-iodo-2'-deoxyuridine, puromycin, and actinomycin D. PMID- 4289890 TI - Inhibition of interferon production by a halogenated pyrimidine derivative: 5 fluoro-2'-deoxyuridine. PMID- 4289891 TI - [On virus differentiation within the herpes- and poxvirus group. (Possibilities and limits of various methods)]. PMID- 4289892 TI - The usefullness of human fibroblast cell lines for the isolation of viruses. PMID- 4289893 TI - Epidemiology of parainfluenza 3 infection in sheep. PMID- 4289894 TI - Epidemiology of group II adenoviruses. PMID- 4289895 TI - Studies in laser destruction of chemically induced primate hepatomas. PMID- 4289896 TI - Determination of glycogen with the anthrone reagent. PMID- 4289897 TI - Osteoclastoma of the heart. PMID- 4289898 TI - [Neonatal mal-adaptation and adrenocortical hormones]. PMID- 4289899 TI - Effect of tranylcypromine on adrenocortical secretion in the dog. PMID- 4289900 TI - Effect of 1-adamantanamine hydrochloride on Rous sarcoma virus in vitro and in vivo. PMID- 4289901 TI - Influence of prednisolone and ACTH on the formation of insulin-binding antibodies. PMID- 4289902 TI - Electron spin resonance studies of radiation damage in deoxyribonucleic acid. PMID- 4289903 TI - Effect of chemical modification of keratin structure on its electron spin resonance spectrum after irradiation. PMID- 4289904 TI - Thin-layer electrophoresis. 3. Studies on the dissipation of heat. PMID- 4289905 TI - Ion exchange in fused salts. II. Distribution coefficients of some alkali metal ions on zirconium phosphate in fused nitrates. PMID- 4289906 TI - Derivatographic studies of gas-chromatographic partition liquids. I. PMID- 4289907 TI - Reagents for the detection of antioxidants on thin layers of silica. PMID- 4289908 TI - Determination of the trisaturated glyceride content of fats by column chromatography of the mercuric acetate adducts on Florisil. PMID- 4289909 TI - The effect of glycerol on the rate of movement of simple sugars on silica gel and cellulose thin layers. PMID- 4289910 TI - The structure and function of the adhesive organ in strigeid trematodes. 3. Apatemon gracilis minor Yamaguti, 1933. PMID- 4289911 TI - Studies on the structure and histochemistry of the male reproductive tract of Aspiculuris tetraptera (Nematoda: Oxyuridea). PMID- 4289912 TI - Organic synthetics for augmentation mammaplasty: their relation to breast cancer. PMID- 4289913 TI - Detection of altered cerebral arterial blood flow using technetium-99m pertechnetate and the gamma-ray scintillation camera. PMID- 4289914 TI - Comparative experimental evaluation of several types of emulsified oily radiopaque materials in the cranial subarachnoid space. PMID- 4289915 TI - [Possibilities of clinical, radiological and histological differentiation between spontaneous and tumoral intracerebral hematomas]. PMID- 4289916 TI - [Considerations on the diagnosis of neurogenic tumors of the mediastinum and on the remote results of their surgical treatment]. PMID- 4289918 TI - [Reflections on a case of tumor of the trachea]. PMID- 4289917 TI - Survey of bovine respiratory diseases with special reference to the serological examination of paired serum samples. PMID- 4289919 TI - [5 Cases of glomus tumors]. PMID- 4289921 TI - [On a case of A cell adenoma of the endocrine pancreas]. PMID- 4289920 TI - A simple method of inducing amoebic liver abscess in hamsters. PMID- 4289922 TI - The introduction of a "reporter" group at the active site of glyceraldehyde-3 phosphate dehydrogenase. PMID- 4289923 TI - The effect of radiation on collagen. I. Electron-spin resonance spectra of 2537-A irradiated collagen. PMID- 4289924 TI - Cytochrome systems in dark-aerobically grown Rhodopseudomonas spheroides. PMID- 4289925 TI - [The role of nicotinamide in the synthesis of NAD in Ehrlich ascites tumor cells]. PMID- 4289926 TI - Purification and properties of a bacteriophage receptor material from Streptococcus faecium. PMID- 4289927 TI - Studies on plasma membranes. II. K+-dependent p-nitrophenyl phosphatase activity of plasma membranes isolated from rat liver. PMID- 4289928 TI - Differences in the association of two glycolytic enzymes with plasma membranes isolated from rat liver and hepatoma. PMID- 4289929 TI - A serological comparison of vegetative cell and ascus walls and the spore coat of Saccharomyces cerevisiae. PMID- 4289930 TI - The effect of hyperbaric oxygen upon aerobic bacteria. I. In vitro studies. PMID- 4289931 TI - The spheroplasts of bordetella pertussis. PMID- 4289932 TI - Influence of clay minerals on microorganisms. I. Montmorillonite and kaolinite on bacteria. PMID- 4289933 TI - Influence of triiodothyronine on plaque production by vesicular stomatitis virus. PMID- 4289934 TI - Deterioration of solutions of reduced nicotinamide adeninedinucleotide (NADH2) during storage. PMID- 4289935 TI - The enzymatic determination of lactic acid in faeces in glycosidase deficiency. PMID- 4289936 TI - A simple method for the separate determination of cortisol and corticosterone in plasma. PMID- 4289937 TI - Tumors of urinary tract origin in the female pelvis. PMID- 4289938 TI - Assay of sex steroids in urine. PMID- 4289939 TI - Preliminary notes on nucleic acid analyses in Rous sarcoma. PMID- 4289940 TI - Comparison of sialic acid derivatives of cell surface and of whole cell in various hepatomata and normal liver in rat. PMID- 4289941 TI - Radiation protection studies with polyethylene. PMID- 4289942 TI - The determination of copper in quartz by neutron activation analysis. PMID- 4289943 TI - Studies on lipoamide dehydrogenase of bakers' yeast. IV. Inactivation by metal ions in the presence of NADH2. PMID- 4289944 TI - The optical rotatory dispersion of myosin A. V. Re-examination of changes in the optical rotatory power of myosin caused by adenosine triphosphate, inorganic pyrophosphate and p-chloro-mercuribenzoate. PMID- 4289945 TI - A new cytochrome in neurophilic granules of rabbit leucocyte. PMID- 4289946 TI - A hypothesis concerning patterns of deoxynucleotide metabolism in tumors in relation to rate of cell proliferation. PMID- 4289947 TI - [Study using the self-consistent molecular field method of the electronic structure of purine and pyrimidine bases of biochemical value]. PMID- 4289948 TI - Immune adherence hemagglutination test as a new sensitive method for titration of animal virus antigens and antibodies. PMID- 4289949 TI - [Conjugated estrogens in the climacteric and in dyshormonal conditions]. PMID- 4289950 TI - [Conjugated estrogens in the climacteric]. PMID- 4289951 TI - [Immunology and prospects regarding the prevalence of Japanese encephalitis]. PMID- 4289952 TI - Susceptibility and immunity in pigeons to Schmidt-Ruppin strain of Rous sarcoma virus. PMID- 4289953 TI - [Results of the treatment of inflammation of the female genital organs with encorton and ACTH]. PMID- 4289954 TI - [Mechanism of action of flavin enzymes]. PMID- 4289955 TI - Renal renin in unilaterally nephrectomized hypertensive rats. PMID- 4289956 TI - [Biological effects of the renin-angiotensin system]. PMID- 4289957 TI - Rabbit uterus as a possible site of renin synthesis. PMID- 4289958 TI - [Demons-Meigs syndrome caused by ovarian tumor secreting hydrating hormones]. PMID- 4289959 TI - [Pregnancy, delivery and chronic adrenal insufficiency. (Apropos of a case of operated Cushing's syndrome)]. PMID- 4289960 TI - [Apropos of a dissecting mole]. PMID- 4289961 TI - Activation of rat-liver microsomal glucose 6-phosphatase by o- and p-tyrosine. PMID- 4289962 TI - Replacement of a phosphoenolpyruvate-dependent phosphotransferase by a nicotinamide adenine dinucleotide-linked dehydrogenase for the utilization of mannitol. AB - Mannitol is dissimilated by Aerobacter aerogenes via an inducible pathway initiated by a phosphotransferase system dependent upon phosphoenolpyruvate as the phosphoryl donor. A mutational block in this pathway can be suppressed either at the phenotypic level by induction of d-arabitol dehydrogenase, an enzyme fortuitously capable of converting mannitol to fructose, or genotypically by a constitutive mutation in the d-arabitol system. PMID- 4289963 TI - Studies on the function of intracellular ribonucleases. IV. Some observations on the properties of ribosomes and polysomes from rat liver and hepatomas. AB - Polysome and ribosome preparations from normal rat liver and from a series of transplantable rat hepatomas of different growth rates were compared. All the hepatomas had a significantly higher percentage of RNA in a polysome preparation than did the normal liver, and the polysome preparations from the tumors, with the exception of the Dunning hepatoma which has a high lipid content, gave a greater yield of RNA and protein per gram of wet tissue than the liver did. Heavier polysomes were considerably less prevalent in the tumors than in the liver, and the tumors contained a larger proportion of monomer and dimer ribosomes than the liver did. Evidence is presented that the increased monomer and dimer ribosome population of the hepatomas studied is not an artifact of preparation, but represents the true intracellular distribution. Ribosomes from normal liver and Morris 5123-D hepatoma were readily dissociated by 20 min' treatment with 1.0 mM EDTA, but ribosomes from the Dunning, Novikoff ascites, and McCoy MDAB hepatomas were little affected by such treatment. With higher concentrations of EDTA, the ribosomes from the Novikoff ascites and McCoy MDAB hepatomas broke down and did not form specific subunits as did ribosomes from liver and the Morris 5123-D hepatoma but rather gave rise to a variety of small degradation products. This behavior is ascribed to a higher RNase content of the Novikoff and McCoy MDAB hepatomas. Dunning hepatoma ribosomes were resistant to 4 mM EDTA. PMID- 4289965 TI - Studies on dispersion of rabbit olfactory cells. PMID- 4289964 TI - Studies on the function of intracellular ribonucleases. V. Ribonuclease activity in ribosomes and polysomes prepared from rat liver and hepatomas. AB - The RNase activity and properties of ribosome and polysome preparations from normal rat liver and some hepatomas have been examined. Polysome and ribosome preparations from the Novikoff, McCoy MDAB, and Dunning hepatomas had considerably higher specific RNase activity than corresponding preparations from normal rat liver, Novikoff ascites, or Morris 5123 hepatomas. The optimum pH of the RNase was approximately 8.5 for all samples tested, and the samples showed no evidence of latent RNase activity when treated with 3 M sodium chloride, EDTA, urea, or p-chloromercuribenzenesulfonic acid. The RNase activity appeared to be associated principally with breakdown products and/or subunits smaller than 80S. In the presence of Mg(++) ions, subunits could reaggregate to form monomer ribosomes indistinguishable from the natural products, but some of the reassociated ribosomes could contain RNase activity which had been bound to the smaller particles. Similar results were obtained with spermine. In the hepatomas, evidence was obtained for the preexistence of considerable amounts of the smaller, RNase-containing subunits in the cell. When a small amount of crystalline bovine pancreatic RNase was added to partly dissociated ribosomes, the RNase was found only in association with the smaller subunits, and little or no enzyme was taken up by ribosomes or polysomes. The results have led to the conclusion that RNase is not a normal constituent of the ribosome or polysome, but that RNase may become associated with these particulates if dissociation and reassociation take place. Some implications of these findings for the stability of messenger RNA and for the mechanism of its breakdown are discussed. PMID- 4289966 TI - A variant of lactate dehydrogenase in somatic tissues of pigeons: physicochemical properties and genetic control. PMID- 4289967 TI - Suitability of collagenase treatment for the radioautographic identification of newly synthesized collagen labeled with 3H-glycine or 3H-proline. PMID- 4289968 TI - On the fine structural demonstration of glucose 6-phosphatase. PMID- 4289969 TI - Evidence for the in vitro transfer of defective Rous sarcoma virus genome from hamster tumor cells to chick cells. PMID- 4289970 TI - Isolation of the nucleic acid of mouse mammary tumor virus (MTV). PMID- 4289971 TI - Separation of three microbial amino acid polymerization factors. PMID- 4289972 TI - Lack of evidence for an inhibitory effect of angiotensin on Na+-K+ adenosinetriphosphatase. PMID- 4289973 TI - Adrenal inhibition in the rat and guinea pig by 2-(p-aminophenyl)-2 phenylethylamine (SK&F 12185). PMID- 4289974 TI - Action of luteinizing hormone on conversion of ovarian cholesterol stores to steroids secreted in vivo and synthesized in vitro by the pseudopregnant rabbit ovary. PMID- 4289975 TI - Broad horizons of community mental health. PMID- 4289977 TI - Group relations conference experience. PMID- 4289976 TI - A mother-child admission to an inpatient psychiatric unit. PMID- 4289978 TI - Resolving conflict through play fantasy. PMID- 4289979 TI - Attitudes of Korean and American mental patients toward mental illness and hospitalization. PMID- 4289980 TI - Speaking out... On: what's new? PMID- 4289982 TI - Crisis intervention. PMID- 4289981 TI - The two sides of pain. I. PMID- 4289983 TI - The relation between dental maturation and physiological maturity. PMID- 4289984 TI - Roentgen and tele-cobalt therapy of cancer of the lung. PMID- 4289985 TI - The action of adrenalin and glucagon on the metabolism of phospholipids in rat liver. PMID- 4289986 TI - The action of insulin on the incorporation of [32P]phosphate in the phospholipids of rat adipose tissue. PMID- 4289987 TI - Phospholipids of yeast. I. Improvements in analysis by two-dimensional strip transfer paper chromatography. PMID- 4289988 TI - Effect of TSH, acetylcholine, epinephrine, serotonin and synkavite on 32-P incorporation into phospholipids in dog-thyroid slices. PMID- 4289989 TI - Biological activities of 3-isoadenosine. PMID- 4289990 TI - Stability of DNA in synchronized cultures of Tetrahymena pyriformis GL. PMID- 4289992 TI - [Analysis of adrenal cortex inhibition of some compounds with glucocorticoid activity]. PMID- 4289991 TI - [On blood concentrations of leukocytes and thrombocytes in iron deficiency]. PMID- 4289993 TI - [Studies of adrenal cortex function following repetition of an aspecific stimulus]. PMID- 4289994 TI - [Role of the spleen in endocrine processes. VI. Influence of nucleotides, metabolites of reticuloendothelial system, on free plasma corticosteroids]. PMID- 4289995 TI - Metabolic integrity of deoxyribonucleohistones. PMID- 4289996 TI - Effect of crystallization upon the reactivity of horse liver alcohol dehydrogenase. PMID- 4289997 TI - [Clinical considerations on hypoglycemia]. PMID- 4289998 TI - Treatment of acute brain syndrome from alcohol with nicotinamide adenine dinucleotide and methaminodiazepoxide. PMID- 4289999 TI - The interaction of neutralized poliovirus with HeLa cells. I. Adsorption. PMID- 4290000 TI - Studies on the neutralization of herpes simplex virus. IV. Properties of virus sensitized with complement-requiring neutralizing (CRN) antibody at 37 degrees and 0 degrees. PMID- 4290001 TI - A comparison of cocal and vesicular stomatitis virus, serotypes New Jersey and Indiana. PMID- 4290002 TI - Differences between the thermal inactivation of picornaviruses at "high" and "low" temperatures. PMID- 4290003 TI - Differential effect of actinomycin D on the infectivity of single- and double stranded poliovirus RNA. PMID- 4290004 TI - Clomiphene treatment of prolonged secondary amenorrhea associated with pituitary gonadotropin deficiency. PMID- 4290005 TI - Effects of clomiphene on adrenal cortical steroidogenesis in dogs. PMID- 4290006 TI - Effect of sympathetic nerve stimulation on the uterine vascular bed. PMID- 4290007 TI - Effect of amantadine hydrochloride on parainfluenza type 1 virus infections in adult volunteers. PMID- 4290008 TI - Structure and biosynthesis of the cell wall lipopolysaccharide of Escherichia coli. PMID- 4290009 TI - Chemical studies on the lipid component of endotoxin, with special emphasis on its relation to biological activities. PMID- 4290010 TI - The mechanism of pyridine nucleotide synthesis in Ehrlich ascites carcinoma and host liver. PMID- 4290011 TI - Cationic antibiotics and phospholipase C as tools in the study of phospholipid structure and function. I. Inhibition of the in vitro clotting system by cationic antibiotics. PMID- 4290012 TI - Cationic antibiotics and phospholipase C as tools in the study of phospholipid structure and function. II. Combined effects of colistin sulfate and phospholipase C on the in vitro blood clotting system. PMID- 4290013 TI - Factors influencing tetrazole reduction by reduced nicotinamide-adenine dinucleotide in pigeon-heart mitochondria. PMID- 4290014 TI - Blood sugar regulation in the hagfish, Myxine glutinosa. PMID- 4290015 TI - Function and cytology of the normal and autotransplanted pars distalis of the hypophysis in the toad Bufo bufo (L). PMID- 4290016 TI - Hepatoblastoma in infancy. Report of a case. PMID- 4290017 TI - The treatment of erythema nodosum leprosum with B.663. A controlled study. PMID- 4290018 TI - Metabolism of Mycobacterium leprae separated from human leprosy nodules. PMID- 4290019 TI - Leprotic nerve abscesses in northern India. PMID- 4290020 TI - Intestinal lymphangiography in vivo. PMID- 4290021 TI - Studies on zinc deficiency: changes in trace elements and enzyme activities in tissues of zinc-deficient rats. AB - Zinc content of testes, bones, esophagus, kidneys, and muscles was decreased, whereas iron content was increased in the testes of zinc-deficient rats compared to restrictedly fed control rats. Histochemical enzyme determinations revealed reduced activities of certain enzymes in the testes, bones, esophagus, and kidneys. In the testes, lactic dehydrogenase (LDH), malic dehydrogenase (MDH), alcohol dehydrogenase (ADH), and NADH diaphorase; in the bones, LDH, MDH, ADH, and alkaline phosphatase; in the esophagus, MDH, ADH, and NADH diaphorase; and in the kidneys, MDH and alkaline phosphatase were decreased in zinc-deficient rats compared to restrictedly fed controls. Succinic dehydrogenase (SDH) revealed no significant changes under the conditions of our experiments in various groups of rats that were investigated. In a "repleted" group of rats, content of zinc in testes and bones increased significantly, compared to the deficient group. The iron content of the testes decreased after repletion with zinc. In the testes, bones, esophagus, and kidneys, the activities of various enzymes increased after repletion with zinc. Inasmuch as the major manifestations of zinc deficiency syndrome in the rat include growth retardation, testicular atrophy, and esophageal parakeratosis, our results suggest that the content of zinc in the above tissues most likely controls the physiological processes through the formation of zinc-dependent enzymes. PMID- 4290022 TI - The effects of secretin, pancreozymin, and gastrin on insulin and glucagon secretion in anesthetized dogs. AB - The effects upon islet hormone secretion of highly purified preparations of secretin and of pancreozymin-cholecystokinin and of a crude gastrin-containing extract of hog antrum have been studied in acutely operated dogs. All three preparations were shown to cause a striking increase in insulin concentration in the pancreaticoduodenal venous plasma after their rapid endoportal injection in anesthetized dogs. With each hormone preparation, the peak in insulin secretion occurred 1 minute after injection, and a rapid decline was observed immediately thereafter. Whereas secretin and gastrin failed to alter significantly the pancreaticoduodenal venous glucagon or arterial glucose concentration, pancreozymin caused a dramatic rise in pancreaticoduodenal venous glucagon concentration, which reached a peak 3 minutes after injection, and hyperglycemia was noted to occur soon thereafter. Endoportal infusion of secretin and pancreozymin for 20 minutes caused responses that were sustained but qualitatively identical to the responses noted after rapid injection of the hormones. The beta-cytotropic effect of secretin was abolished by the infusion of epinephrine. These results could not be attributed to the small degree of contamination of the enteric hormone preparations with insulin or glucagon, and it would appear that secretin, pancreozymin, and probably gastrin have insulin releasing activity and that pancreozymin has, in addition, glucagon-releasing activity.The demonstration that these three hormones possess insulin-releasing activity suggests that there is in the gastrointestinal tract a chain of betacytotropic hormones from antrum to ileum that is capable of augmenting insulin secretion as required for disposal of substrate loads. It is suggested that the existence of this "entero-insular axis" prevents high substrate concentrations that would otherwise follow ingestion of large meals were the insular response entirely a function of arterial substrate concentration. PMID- 4290023 TI - Comparison of the actions of vitamins D2 and D3 in the chick with their retention in serum, liver and intestinal mucosa. PMID- 4290024 TI - Altered properties of deoxyribonucleic acid nucleotidyltransferase after infection of mammalian cells with herpes simplex virus. PMID- 4290025 TI - Efficacy of "Viractin" in preventing respiratory disease. PMID- 4290026 TI - Neoplasms induced by Rous sarcoma virus in New World monkeys. PMID- 4290027 TI - Oxidative enzyme activity in Candida albicans. PMID- 4290028 TI - A histochemical and fine structure study of the developing rat choroid plexus. PMID- 4290029 TI - Effectiveness of kanamycin in management of gram-negative septicemia in children with malignant disease. PMID- 4290030 TI - Bacteriology of tuberculosis with special reference to kanamycin and related drugs. PMID- 4290031 TI - Kanamycin: its therapeutic record in pulmonary tuberculosis in France and other European countries. PMID- 4290033 TI - [Typing of the foot-and-mouth disease virus]. PMID- 4290032 TI - Tetracosactrin. PMID- 4290034 TI - Vesicular stomatitis virus: relationship between strains of the Indiana serotype. PMID- 4290035 TI - The inactivation of pertussis protective antigen, histamine sensitizing factor, and lipolysaccharide by sodium metaperiodate. PMID- 4290036 TI - Comparison of nicotinamide adenine dinucleotide synthesis by Mycobacterium tuberculosis and Mycobacterium bovis. PMID- 4290037 TI - The treatment of peripheral nerve lesions of the hand in leprosy. PMID- 4290038 TI - Changing a hospital environment from a homosexual environment to a heterosexual environment. PMID- 4290039 TI - Changes of nucleoside phosphatase activity in the hypoglossal nucleus during nerve regeneration. PMID- 4290040 TI - Pyruvic and lactic acid metabolism in muscular dystrophy, neuropathies and other neuromuscular disorders. PMID- 4290041 TI - Synthesis and reactions of 3,11-beta-dihydroxy-delta-4-androsten-17-one. PMID- 4290042 TI - Biosynthesis of bacterial glycogen. IV. Activation and inhibition of the adenosine diphosphate glucose pyrophosphorylase of Escherichia coli B. PMID- 4290043 TI - Biosynthesis of uridine diphosphate D-xylose. 3. Uridine diphosphate D-glucose dehydrogenase of Cryptococcus laurentii. PMID- 4290044 TI - Studies of the triplet state of proteins by electron spin resonance spectroscopy. PMID- 4290045 TI - [Immunological variants of foot-and-mouth disease virus. Definition. Method of determination. Application to "O Flanders" (1947) and "O Lausanne" (1965) strains]. PMID- 4290046 TI - Studies of collagenase activity in periodontal diseases. PMID- 4290047 TI - Growth behavior of spontaneous hepatoma in C3HO mice. PMID- 4290048 TI - Quantitative determination of alpha- and gamma-2,4-dinitrophenyl-isomers of alpha,gamma-diaminobutyric acid with an automatic amino acid analyzer as a method of studying N-alpha--N-gamma migration in peptides of alpha,gamma-diaminobutyric acid and polymyxin M. PMID- 4290049 TI - Pleomorphic adenoma (mixed tumor) of the palate. PMID- 4290050 TI - Distant metastases to the jaws: report of four cases. PMID- 4290051 TI - [Leuco-erythroblastosis with anaemia and thrombocytopenia in ventricular carcinoma metastasizing to the bone marrow (Jarcho's syndrome)]. PMID- 4290052 TI - Studies on metastasis of cancer. XIX. Experimental studies on the mechanism of hematogenous metastasis formation, with reference to the results of repeated intravenous inoculation of small number of tumor cells. PMID- 4290053 TI - Brain and spinal cord tumors of children. PMID- 4290054 TI - The isolation of parainfluenza. 3. Virus from the testicles of an infertile bull. PMID- 4290055 TI - Milkers' nodule virus infection and its resemblance to orf. PMID- 4290056 TI - [Carcinomatous neuropathies]. PMID- 4290057 TI - Microchemical architecture of human isocortex. PMID- 4290058 TI - Daunomycin, an antitumor antibiotic, in the treatment of neoplastic disease. Clinical evaluation with special reference to childhood leukemia. PMID- 4290059 TI - Hepatoblastoma and hepatocarcinoma in infancy and childhood. Report of 47 cases. PMID- 4290060 TI - Relationship between viral neurotropism and oncolysis. I. Study of vaccinia virus. PMID- 4290061 TI - Relationship between viral neurotropism and oncolysis. II. Study of influenza virus. PMID- 4290062 TI - Factors influencing serum glycoprotein levels in the mouse and rat. PMID- 4290063 TI - Incorporation of bicarbonate-14 C into pyrimidines and into ribonucleic acid of the Novikoff ascites tumor cell. PMID- 4290064 TI - An electron microscopic study of the leukemia virus in AKR and hybrid mice inoculated with ascites passage or tissue-cultured leukemic cells. PMID- 4290065 TI - Enzymic lesions of nicotinamide adenine dinucleotide biosynthesis in hepatomas and in azo dye carcinogenesis. PMID- 4290066 TI - Plasma testosterone determination in some cases of hirsutism and virilism of adrenal origin. PMID- 4290067 TI - Abdominal adenovirosis and appendicitis. PMID- 4290068 TI - The effect of previous stimulation of the adrenal cortex by adrenocorticotrophin on the function of the pituitary-adrenocortical axis in response to stress. AB - 1. There appear to be at least two peripheral regulators affecting normal physiological adrenal function during repeated stimulation with adrenocorticotrophin (ACTH).2. There is a tachyphylaxis to ACTH if the stimulation of the adrenal gland is frequent. This may be due to alteration or saturation of the trapping mechanism for acceptance of ACTH by the tissue. There also may be inhibitors at the adrenal level. The results obtained could also be explained on the basis of end product inhibition by corticosterone on the process of synthesis or by the presence of a destructive enzyme for ACTH.3. If the amounts of ACTH released or injected are sufficiently great the gland is capable of synthesizing more steroid but adrenocortical dynamics do not allow an immediate release of the steroid into the peripheral circulation. Thereby high levels of steroid in the plasma are maintained for longer periods rather than increased. PMID- 4290069 TI - Electric injuries to peripheral nerves in animals. A preliminary report. PMID- 4290070 TI - Characterization of an avian leukosis virus isolate. PMID- 4290071 TI - Electron transport function of a heat-stable protein and a flavoprotein in the oxidative decarboxylation of glycine by Peptococcus glycinophilus. PMID- 4290072 TI - The isolation and characterization of a trisaccharide from porcine submaxillary glycoproteins. PMID- 4290073 TI - Circulatory responses to angiotensin in man. PMID- 4290074 TI - Persistent neuropathy following chronic use of glutethimide. PMID- 4290075 TI - Multiple antibodies appearing after massive transfusion of apparently compatible blood. PMID- 4290076 TI - Inhibition of adrenal corticosteroid synthesis by aminoglutethimide: studies of the mechanism of action. PMID- 4290077 TI - Effects of amino-glutethimide on adrenal function in man. PMID- 4290078 TI - Plasma growth hormone levels in spontaneous hypoglycemia. PMID- 4290079 TI - ACTH stimulation of aldosterone secretion in normal subjects and in patients with chronic adrenocortical insufficiency. PMID- 4290080 TI - Effects of progesterone and estrogen on the sensitivity to angiotensin II. PMID- 4290081 TI - [Case of Krukenberg's tumor with difficulty in differentiating it from acute diffuse interstitial pulmonary fibrosis]. PMID- 4290082 TI - [The antidiuretic effect of angiotensin in diabetes insipidus]. PMID- 4290083 TI - [Urology in childhood]. PMID- 4290084 TI - Anisonucleolinosis in mammalian cell cultures. PMID- 4290085 TI - [The modern treatment of various forms of epileptic attacks and other symptoms of epileptic illnesses]. PMID- 4290086 TI - [Effects of a cationic surface-active agent on the ultrastructure of Yoshida's ascitic hepatoma "in vivo"]. PMID- 4290087 TI - [Observations on the appearance and growth of poliovirus plaques]. PMID- 4290088 TI - The effect of ACTH on the plasma and urinary corticoids in normal elderly persons and in patients with senile psychosis. PMID- 4290089 TI - Observations on the association of enteric viruses and bacteria with diarrhea. PMID- 4290090 TI - Histochemical demonstrations of actinomycin-induced changes of certain oxidative and hydrolytic enzymes of rat incisor pulps. PMID- 4290091 TI - The reaction of DNA with water-soluble carbodiimide and enzyme sensitivity of modified DNA. PMID- 4290092 TI - Effect of angiotensin on the renal transport of sodium in essential hypertension. PMID- 4290093 TI - [Management of patients with multiple sclerosis]. PMID- 4290094 TI - Further observations of the angiotensin vasopressive effect in rabbits. PMID- 4290095 TI - Islet cell tumor of the pancreas with reversible watery diarrhea and achylorhydraia. PMID- 4290096 TI - Bilateral non-chromaffin tympano-jugular paraganglioma. PMID- 4290097 TI - Effect of chronic ethanol feeding on rat liver phospholipid. PMID- 4290098 TI - Effect of vitamin D3 on the in vitro transport of calcium by the chick intestine. PMID- 4290099 TI - A revised and more detailed hypothesis for the mechanism of oxidative phosphorylation at the diphosphopyridine nucleotide-flavin level. PMID- 4290100 TI - [Action of beta-angiotensin II on cardiac dynamics. Indirect study with the Blumberger method]. PMID- 4290101 TI - Pyridoxal and pyridoxamine phosphate breakdown by an acid phosphatase preparation. PMID- 4290102 TI - [Experimental herpetic uveitis. Thoughts on a model]. PMID- 4290103 TI - Neuropathy in lymphoblastic leukemia treated with vincristine. PMID- 4290104 TI - Mycoplasma (PPLO) isolated from Rous sarcoma virus. PMID- 4290105 TI - Effect of small doses of carrier iodide upon the organic binding of radioactive iodine by the human thyroid gland. PMID- 4290106 TI - Herpes virus specified ribonucleic acids. PMID- 4290107 TI - Damage of peripheral nerve associated with orthopedic injuries. PMID- 4290108 TI - Mucinous adenocarcinoma of the urinary tract. PMID- 4290109 TI - Visiting nurse consultation in a community psychiatry program. PMID- 4290110 TI - Crisis: the psychiatric nurse intervenes. PMID- 4290111 TI - A student's view of involutional psychosis. PMID- 4290113 TI - Community psychiatry, goals, and the psychiatric nurse. PMID- 4290114 TI - New Jersey's Department of Institutions and Agencies' Nursing Services. PMID- 4290112 TI - A program of rehabilitation for the chronic female patient. PMID- 4290115 TI - International trends. PMID- 4290116 TI - Speaking out. On: the diploma R.N. and further education--a time for reassessment? PMID- 4290117 TI - The two sides of pain. II. PMID- 4290118 TI - Clinical pathologic conference No. 2. PMID- 4290119 TI - [Silica and its allotropic forms. Contribution to study of their use in dentistry]. PMID- 4290120 TI - [Cytologic study of the normal epidermis]. PMID- 4290121 TI - Defined media and development of mammalian eggs in vitro. PMID- 4290122 TI - Herpes simplex encephalitis treated with intravenous idoxuridine. PMID- 4290123 TI - Enzyme histochemistry in experimental diabetes mellitus. 3. Findings on several enzyme activities in pancreatic islet cells of chronic diabetic rabbits. PMID- 4290124 TI - An attempt to evaluate the steroidogenic activity of synthetic adrenocorticotropic peptides: the circulation method. PMID- 4290125 TI - Enzyme histochemistry in experimental diabetes mellitus. II. Findings on several enzyme activities in the parenchymal organs, muscular system, intestine, and adrenal gland in diabetic rabbits. PMID- 4290126 TI - Puromycin potentiation of corticotropin-induced insulin release. PMID- 4290127 TI - Response of the anterior pituitary-adrenocortical axis to purified CRF. PMID- 4290128 TI - Effect of renin on adrenocortical sensitivity to ACTH and angiotensin II in dogs. PMID- 4290129 TI - Liver glycogenesis, glycogen synthetase and adrenal responsiveness of rats exposed to acceleration stress. PMID- 4290130 TI - Increased ACTH release without increased synthesis. PMID- 4290131 TI - Comparison of plasma corticotropin concentration in intact and adrenalectomized dogs and cats during hemorrhage. PMID- 4290132 TI - Characteristics of the steroid binding site: a method to evaluate sterospecificity of hydrogen transfer by steroid dehydrogenases. PMID- 4290133 TI - The electroencephalogram in advanced senile dementia. PMID- 4290134 TI - Lysosomes in Tetrahymena pyriformis. I. Some properties and lysosomal localization of acid hydrolases. PMID- 4290135 TI - Direct evidence for the binding or compartmentalization of acid-soluble metabolites in oocyte cells. PMID- 4290136 TI - Gluconeogenesis in mouse kidney cortex. Effect of age and fasting on glucose production and enzyme activities. PMID- 4290138 TI - The role of Schwann cells in the formation of onion bulbs found in chronic neuropathies. PMID- 4290137 TI - Acute hemorrhagic leukoencephalitis of herpes simplex-virus type. Histological and electronmicroscopical findings. PMID- 4290139 TI - Perineural fibroblastomas: their fine structure and biology. PMID- 4290140 TI - The histopathology of the dilute lethal strain of mice. PMID- 4290141 TI - Cytochemical and electron microscopic study of a case of Jakob-Creutzfeldt disease. PMID- 4290142 TI - Ultramicroscopic and histochemical studies of spongy degeneration (van Bogaert and Bertrand type). PMID- 4290143 TI - Amyloidosis confined to the central and peripheral nervous systems. PMID- 4290144 TI - Experimental allergic peripheral neuritis studied in vitro. PMID- 4290145 TI - Effects of isoprenaline treatment of secretory responses and respiratory enzymes of the submazillary gland of the rat. PMID- 4290146 TI - An immunofluorescence study of the action of antibody in experimental intracerebral infection of mice with Bordetella pertussis. PMID- 4290147 TI - Superficial hidradenoma and basal-cell carcinoma. PMID- 4290148 TI - Virilizing ovarian tumor in a 2 1/2-year-old girl. PMID- 4290149 TI - Metabolism of tritiated vitamin D3 in familial vitamin D-resistant rickets with hypophosphatemia. PMID- 4290150 TI - Histoenzymatic studies of vessels in hypertensive rats. PMID- 4290151 TI - Diagnosis of nasopharyngeal angiofibromata by carotid arteriography. PMID- 4290152 TI - Cylindroma of the right maxillary antrum. Case report. PMID- 4290153 TI - Studies on urinary phenolic compounds in man. V. Homovanillic and vanillylmandelic acids in children without functional neural tumors. PMID- 4290154 TI - [Studies on the hemagglutination and hemadsorption spectrum of para-influenza viruses]. PMID- 4290155 TI - [Studies on the early phase of virus reproduction; demonstration of a resistance to the influence of various inhibitors]. PMID- 4290156 TI - [Contribution to the technic for serodiagnosis of adenovirus infections. Utilization of stable sensitized blood cell suspensions]. PMID- 4290157 TI - Histochemical observations in preclinical mouse muscular dystrophy. PMID- 4290158 TI - [Typing of the foot-and-mouth disease virus. Cumulative quarterly report]. PMID- 4290159 TI - The isolation of mitochondria from the colourless alga Prototheca zopfii. PMID- 4290160 TI - Differentiation of the cell membrane in embryonic chick blood cells. PMID- 4290161 TI - Cytology of islet tumours and hyperplasias associated with the Zollinger-Ellison syndrome. PMID- 4290162 TI - Intraneural ganglion of the tibial nerve. A case report. PMID- 4290163 TI - Peripheral neuritis as a complication of infectious mononucleosis. Report of a case. PMID- 4290164 TI - The occurrence of granulosa and theca tumours in clinically normal ovaries. A study of 25 cases. PMID- 4290165 TI - Hormonal activity with ovarian tumours. PMID- 4290166 TI - Pregnancy in a case of adrenal hyperplasia. Case report and discussion. PMID- 4290168 TI - Cytomegalovirus infection in an adult. PMID- 4290167 TI - Radiographic simulation of certain solid tumors of the renal corpus to renal cyst. PMID- 4290169 TI - [Case of hyperinsulinemia caused by Langerhans' tumor]. PMID- 4290170 TI - [Benign and malignant primary epithelial tumors in the oral cavity]. PMID- 4290171 TI - The decrease in size and synthetic activity of poliovirus polysomes late in the infectious cycle. PMID- 4290172 TI - The inactivation of foot-and-mouth disease virus at ionic-strength dependent isoelectric points. PMID- 4290173 TI - Antigenic characteristics of the interaction between Rous sarcoma virus and mammalian cells. Complement-fixing and transplantation antigens. PMID- 4290174 TI - Disaggregation of HeLa cell polysomes after infection with poliovirus. PMID- 4290175 TI - Potentiation of the action of interferon by extracts of Escherichia coli. PMID- 4290176 TI - Study of intracellular SV40 antigens by indirect immunoferritin technique. PMID- 4290177 TI - Detection of avian leukosis viremia in chicks by transplantation of Bryan strain Rous sarcoma hamster tumors. PMID- 4290178 TI - Prevention of testicular degeneration in alloxanized rats by the use of cortisone. PMID- 4290179 TI - Restless legs and orthostatic hypotension in primary amyloidosis. PMID- 4290180 TI - Electrodiagnostic study of a patient with peripheral neuropathy after nitrofurantoin therapy. PMID- 4290181 TI - [Properties of phosphofructokinase from ascites tumor cells]. PMID- 4290182 TI - [Enzymatic catalysis of cyanide addition to nicotinamide-adenin-nucleotide]. PMID- 4290183 TI - Endogenous nucleotides of mitochondria participating in phosphate transfer reactions as studied with 32P labelled orthophosphate and ultramicro scale ion exchange chromatography. PMID- 4290184 TI - Fluoride and the metabolism of salivary bacteria. PMID- 4290185 TI - Strain MC29 avian leukosis virus. Myelocytoma, endothelioma, and renal growths: pathomorphological and ultrastructural aspects. PMID- 4290186 TI - Lactate dehydrogenase isoenzymes in the diagnosis of human benign and malignant brain tumors. PMID- 4290187 TI - Ultrastructure of meningeal tumors induced in dogs with Rous sarcoma virus. PMID- 4290188 TI - Epinephrine potentiation in isolated rabbit aortic strips. PMID- 4290189 TI - [A study on chemotherapy using so-called tertiary drugs for severe cavitary pulmonary tuberculosis failed to respond to chemotherapy by primary and secondary antituberculous drugs]. PMID- 4290190 TI - Electron paramagnetic resonance spectra of bone and its major components. PMID- 4290191 TI - Electron spin resonance in surviving rat tissues. PMID- 4290192 TI - Complementation between a defective monkey cell-adapting component and human adenoviruses in simian cells. PMID- 4290193 TI - Foot-and-mouth disease virus-induced ribonucleic acid polymerase in baby hamster kidney cells. PMID- 4290194 TI - Transplant immunity to polyoma virus-induced tumor cells. IV. A polyoma strain defective in transplant antigen induction. PMID- 4290195 TI - Heterogeneity of apparently empty poliovirus particles stained with phosphotungstic acid after heating of the virus at "low" temperature. PMID- 4290196 TI - [Further cases of foot-and-mouth disease virus infections in man]. PMID- 4290197 TI - [Study on the spreading of vaccine viruses (enteroviruses) by wild birds]. PMID- 4290198 TI - [New model studies of intestinal defenses against infection]. PMID- 4290199 TI - [On the antigen-antibody reaction of in vitro neutralization of poliomyelitis virus]. PMID- 4290200 TI - [On the ability of hydrazine to inhibit poliovirus I in vitro]. PMID- 4290201 TI - [Study on the action of the common antibiotics on poliovirus I and vaccinia virus]. PMID- 4290202 TI - Observations on patients with cerebral astrocytoma (glioblastoma multiforme) treated by irradiation under whole-body hypothermia. PMID- 4290203 TI - Carcinogenicity of dimethylnitrosamine in Swiss mice. PMID- 4290204 TI - Experimental diphtheritic neuropathy in the rat. PMID- 4290205 TI - Improvements in a method of growing respiratory viruses in organ cultures. PMID- 4290206 TI - Inhibition of the growth of influenza and rubella viruses by amines and ammonium salts. PMID- 4290207 TI - Paravertebral widening in cases of neuroblastoma. PMID- 4290208 TI - Syntheses and antiviral effect of (amidinocarbamoyl)pyridine derivatives. PMID- 4290209 TI - The use of angiotensin in the assessment of left ventricular function in fixed orifice aortic stenosis. PMID- 4290210 TI - Peripheral lymphatico-venous anastomoses. Report of two cases. PMID- 4290211 TI - Effect of angiotensin on urea reabsorption in man. PMID- 4290212 TI - Adrenocortical response to high dosage ACTH therapy in patients with multiple sclerosis. PMID- 4290213 TI - Testicular sterols. VI. Incorporation of mevalonate into squalene and sterols by cell-free preparations of testicular tissue. PMID- 4290214 TI - Some properties of partially purified mammalian adenosine kinase. PMID- 4290215 TI - Biosynthesis of diphosphopyridine nucleotide. The purification and the properties of diphospyridine nucleotide synthetase from Escherichia coli b. PMID- 4290216 TI - The localization of acyl coenzyme A-carnitine acyltransferases in rat liver cells. PMID- 4290217 TI - Muramic acid phosphate as a component of the mucopeptide of Gram-positive bacteria. PMID- 4290218 TI - Acetyl coenzyme A and acetylcarnitine concentration and turnover rates in muscle and liver of the ketotic rat and guinea pig. PMID- 4290219 TI - Beef heart malic dehydrogenases. VI. A pH-dependent transition observed in the presence of reduced diphosphopyridine nucleotide. PMID- 4290220 TI - Studies on the electron transfer system. 68. Formation of membranes as the basis of the reconstitution of the mitochondrial electron transfer system. PMID- 4290221 TI - Crystalline quinolinate phosphoribosyltransferase. II. Properties of the enzyme. PMID- 4290222 TI - Mouse brain phosphoserine phosphohydrolase and phosphotransferase. PMID- 4290223 TI - Identification of alpha,alpha-trehalose 6,6'-dimannosylphosphate and alpha maltose 1-phosphate of Mycobacteria. PMID- 4290224 TI - Sugar phosphate phosphohydrolase. I. Substrate specificity, intracellular localization, and purification from Neisseria meningitidis. PMID- 4290225 TI - Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. PMID- 4290226 TI - The effect of magnesium ion concentration on the pH optimum of the spinach leaf alkaline fructose diphosphatase. PMID- 4290227 TI - Androgen production in hypogonadal men. PMID- 4290228 TI - Serologic survey of man for avian leukosis virus infection. PMID- 4290229 TI - Some aspects of neuromuscular blockade by polymyxin B. PMID- 4290230 TI - Therapeutic advantages of an inotropic vasodilator in endotoxin shock. PMID- 4290231 TI - [Value of the hypertensin test in the diagnosis of nephrogenic hypertension]. PMID- 4290232 TI - Malignant hepatoma--controlled therapeutic trials. South African primary liver cancer research group. Initial report. PMID- 4290233 TI - Cancer of the nose and paranasal sinuses. PMID- 4290234 TI - Cancer of the stomach. PMID- 4290235 TI - Pancreatoduodenectomy for periampullary cancer. PMID- 4290236 TI - Cancer of the rectum and sigmoid. PMID- 4290237 TI - One-year aetiological study of nondiphtheritic croup. PMID- 4290238 TI - Nodular theca-lutein hyperplasia of pregnancy (so-called "pregnancy luteoma"). A clinical and pathologic study of 15 cases. PMID- 4290239 TI - Postoperative intussusception in infants and children. PMID- 4290240 TI - [Change in the inhibiting activity of methyl-glyoxalbisguanylhydrazone (methyl GAG) on the multiplication of poliovirus cultured in cells rendered resistant to methyl-GAG]. PMID- 4290241 TI - The neuromuscular function in patients with malignant tumours. Electromyographic and histological study. PMID- 4290242 TI - Osseous metastasis as the only clinical manifestation of primary cancer of the liver. PMID- 4290243 TI - Acquired hemolytic anemia. A review of 26 cases, including 5 of the hemolytic uremic syndrome, with emphasis on the usefulness of steroids in therapy. PMID- 4290244 TI - Ethanol-induced hypoglycemia. II. Mechanism of suppression of hepatic gluconeogenesis. PMID- 4290245 TI - D-myoinositol 1-phosphate as product of cyclization of glucose 6-phosphate and substrate for a specific phosphatase in rat testis. PMID- 4290246 TI - Catalytic properties and specificity of the extracellular nuclease of Staphylococcus aureus. PMID- 4290247 TI - Malate dehydrogenases. 3. Alteration of catalytic properties during purification of Bacillus subtilis malate dehydrogenases. PMID- 4290248 TI - The reversible dissociation of the alkaline phosphatase of Escherichia coli. 3. Properties of antibodies directed against the subunit. PMID- 4290249 TI - The biosynthesis of D-apiose in Lemna minor. PMID- 4290250 TI - Simulation of the action of stimulatory agents on mitochondrial respiration. PMID- 4290251 TI - Current cancer concepts. Therapeutic vs prophylactic castration. PMID- 4290252 TI - Field ion microscopical imaging of biomolecules. AB - specimen molecules are protected from field desorption by embedding them in a platinum matrix, with the use of electrolytic codeposition on tungsten tips. High resolution helium ion images are obtaind when the biomolecules are exposed during gradual removal of surface layers by controlled field evaporation. Structured images of individual molecules of coenzyme I and vitamin B(12)are seen. PMID- 4290253 TI - [The effect of corticosteroids and ACTH on the system of hypophysis--adrenals]. PMID- 4290254 TI - [EEG changes in limited gliomas of the large hemispheres seated in the cerebral cortex and subcortical white matter]. PMID- 4290255 TI - [The importance of the DTP sign in the early diagnosis of injuries of peripheral nerves]. PMID- 4290256 TI - [A study of the enzymes of the toxic Cl. perfringens complex, their formation and interaction]. PMID- 4290257 TI - [Causes and pathological significance of mesenteric adenitis]. PMID- 4290258 TI - Persistence of viral antibodies in patients with chronic bronchitis. PMID- 4290259 TI - Trial of ascorbic acid in prevention of colds. PMID- 4290260 TI - Quantitative evaluation of local blood flow of the adenohypophysis in rats. PMID- 4290261 TI - Tissue phospholipid distribution in adrenalectomized rats. PMID- 4290262 TI - The effect of cortisone on ribonucleic acid polymerase and ribonuclease during development: coincidental evidence for the identity of ribonucleic acid polymerase with the "operator" gene. PMID- 4290263 TI - Immunofluorescent localisation of a growth hormone-like factor in normal and abnormal syncytiotrophoblast. PMID- 4290264 TI - [Influence of blood flow velocity and ACTH stimulation on the adreno-cortical secretion]. PMID- 4290265 TI - [Bacteriological studies for the determination of the present distribution of Cl. perfringens in nature and in the human organism]. PMID- 4290266 TI - [Massive epulis in a newborn (congenital gingival myoblastoma)]. PMID- 4290267 TI - Isolation of parainfluenza-3 virus from water buffaloes in Egypt. PMID- 4290268 TI - [Results of nephrotic syndrome therapy in children]. PMID- 4290269 TI - Renal content of renin-like material and pressor reactivity of rats with chronic pyelonephritis. PMID- 4290270 TI - Effect of blood sugar levels on glycogen content of hypophysis and adrenal glands. PMID- 4290271 TI - Specificity of a neuraminidase activity of Sendai virus. PMID- 4290272 TI - Prevention of SV40 virus tumorigenesis by irradiated, disrupted and iododeoxyuridine treated tumor cell antigens. PMID- 4290273 TI - Influence of vitamin B12 and methionine on levels of folic acid compounds and folate enzymes in rat liver. PMID- 4290274 TI - Isolation of an unclassified enterovirus from healthy children. PMID- 4290275 TI - Rhinovirus infection in nursery and kindergarten children. New rhinovirus serotype 54. PMID- 4290276 TI - Effect of statolon on Friend virus leukemia in mice. PMID- 4290277 TI - Antiviral substances in plants of the mint family (labiatae). I. Tannin of Melissa officinalis. PMID- 4290278 TI - Antiviral substances in plants of the mint family (labiatae). 3. Peppermint (Mentha piperita) and other mint plants. PMID- 4290279 TI - Human cytomegalovirus. Studies on the mechanism of viral cytopathology and inclusion body formation. PMID- 4290280 TI - Effects of multiplicity of poliovirus infection of HeLa cells upon regulation of DNA synthesis. PMID- 4290281 TI - Oxidative enzyme content of kidneys from normal and aminonucleoside-nephrotic rats. PMID- 4290282 TI - Restriction of nonglucosylated T-even bacteriophage: properties of permissive mutants of Escherichia coli B and K12. PMID- 4290283 TI - On the classification of bovine parainfluenza 3 viruses. PMID- 4290284 TI - Separation of infectious Varicella-Zoster virus from human embryonic lung fibroblasts. PMID- 4290285 TI - Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. PMID- 4290286 TI - Histochemical studies of steroid 3-beta-ol dehydrogenases of the human ovaries. PMID- 4290287 TI - Primary chemotherapy for nonmetastatic gestational trophoblastic neoplasms. PMID- 4290288 TI - The use of methotrexate in the treatment of trophoblastic diseases, especially choriocarcinoma. PMID- 4290289 TI - Reduplication of nuclear membranes in tissue-culture cells infected with guinea pig cytomegalovirus. PMID- 4290291 TI - Respiratory virus vaccines. VI. Serologic responses to heptavalent vaccine among young children in families. PMID- 4290290 TI - Correlation of immunology and histopathology of tumors induced by defective SV40 adenovirus hybrids. PMID- 4290292 TI - Corticoid therapy for pretibial myxedema. Observations on the long-acting thyroid stimulator. PMID- 4290293 TI - [Enzymatically catalyzed mutarotation of aldoses. Studies on aldose-1-epimerase from E. coli]. PMID- 4290294 TI - [Transformation of alpha-nicotinamide-adenin-dinucleotide into the beta isomer]. PMID- 4290295 TI - Studies on erythropoietic action of angiotensin II. PMID- 4290296 TI - Erythrocytosis associated with hepatocellular carcinoma. PMID- 4290297 TI - [Possible use of lysozyme in benign lymphoreticulosis due to inoculation]. PMID- 4290298 TI - Inhibition of enzymatic synthesis of epinephrine by low doses of glucocorticoids. PMID- 4290299 TI - Maintenance of pregnancy in protein-deficient rats by adrenocortical steroid or ACTH administration. PMID- 4290300 TI - Effects of ACTH on adrenal RNA synthesis. PMID- 4290301 TI - Inhibition of adrenal protein synthesis by steroids in vitro. PMID- 4290302 TI - Effect of drugs related to alpha-ethyltryptamine on stress-induced ACTH secretion in the dog. PMID- 4290303 TI - Adrenal and plasma corticosterone and vitamin A in rat adrenal glands during postnatal development. PMID- 4290304 TI - Maturation of the circadian rhythm of plasma corticosterone in the rat. PMID- 4290305 TI - Acid mucopolysaccharide alterations in experimental exophthalmos. PMID- 4290306 TI - Corticotrophin secretion by ectopic pituitary glands. PMID- 4290307 TI - Role of the fetal pituitary and adrenal glands in the development of the fetal thymus of the rabbit. PMID- 4290309 TI - [A case of adenoma of the main bronchus with an unilateral clear lung]. PMID- 4290308 TI - [The effect of adrenal hormones on the resistance of the body to staphylococcal exotoxin and E. coli endotoxin]. PMID- 4290310 TI - Binding by glutamate dehydrogenase of reduced diphosphopyridine nucleotide. Effects of regulatory ("allosteric") reagents and ionic strength. PMID- 4290311 TI - An electron spin resonance study of microsomal Fe. PMID- 4290312 TI - Skeletal muscle lipids. 3. Analysis of the functioning of skeletal muscle lipids during fasting. PMID- 4290313 TI - Rat liver glutamyl ribonucleic acid synthetase. II. Further properties and anomalous pyrophosphate exchange. PMID- 4290314 TI - Free adenosine diphosphate as an intermediary in the phosphorylation by creatine phosphate of adenosine diphosphate bound to actin. PMID- 4290315 TI - Diamine oxidase from pig kidney. Improved purification and properties. PMID- 4290316 TI - Nicotinamide adenine dinucleotide kinase from Azotobacter vinelandii. I. Purification and properties of the enzyme. PMID- 4290317 TI - Studies of the acetyl coenzyme A synthetase reaction. V. The requirement for monovalent and divalent cations in partial reactions involving enzyme-bound acetyl adenylate. PMID- 4290318 TI - Steroid content and synthesis in a virilizing luteoma. PMID- 4290319 TI - Gonadal malignancy in gonadal dysgenesis: papillary pseudomucinous cystadenocarcinoma in a patient with Turner's syndrome. PMID- 4290320 TI - Addison's disease in association with idiopathic hypoparathyroidism. PMID- 4290321 TI - Quantitative analysis of urinary 11-deoxy-17-ketosteroids and pregnanediol by gas liquid chromatography. PMID- 4290322 TI - Evaluation of the efficiency of 11-beta-hydroxylation of 11-deoxycortisol in human subjects. PMID- 4290323 TI - A phenylalanine-lysine-vasopressin test of ACTH release. PMID- 4290324 TI - Morphine and the incorporation of Pi32 into brain phospholipids of nontolerant, tolerant and abstinent guinea pigs. PMID- 4290325 TI - Effects of potassium deficiency on experimental renovascular hypertension. PMID- 4290326 TI - Subcellular distribution and enzyme changes following subacute copper intoxication. PMID- 4290327 TI - Relapsing polychondritis. Report of a case. PMID- 4290328 TI - Further experiences with cryosurgery in otolaryngology. PMID- 4290329 TI - Intratympanic glomus tumors--diagnostic work-up and new surgical approach. PMID- 4290330 TI - Fungal metabolites as potential carcinogens, with particular reference to their role in the aetiology of hepatoma. PMID- 4290331 TI - Steroid-sensitive single neurons in rat hypothalamus and midbrain: identification by microelectrophoresis. AB - Minute amounts of Na-dexamethasone-21-phosphate administered by microelectrophoresis to the immediate extracellular environment promptly suppressed electrical activity of 15 out of 115 hypothalamic and mesencephalic neurons, the effect being readily reversible. Such neurons marked with fast green were found to lie in circumscribed areas of the periventricular gray of the third ventricle and aqueduct, and may represent a site of action of adrenocortical steroids in the regulation of corticotrophin releasing factor and/or adrenocortico-tropin secretion by negative feedback. PMID- 4290332 TI - Angiotensinase activity in pregnant and nonpregnant women. PMID- 4290333 TI - Paget's disease of the vulva associated with adenocarcinoma developing in a hidradenoma papilliferum. PMID- 4290334 TI - Studies on Japanese B encephalitis virus vaccines from tissue culture. IX. Human response to a hamster-kidney tissue-culture inactivated vaccine. PMID- 4290335 TI - Plasma cortisol response to synacthen (beta-1-24 Ciba) at different times of the day in patients with rheumatic diseases. PMID- 4290336 TI - [Deamination of L-alanine in normal tissues and malignant tumors]. PMID- 4290338 TI - [Desoxyribonuclease I and II activity of the liver and spleen during experimental mouse hepatitis caused by MHV-3 virus]. PMID- 4290337 TI - [The substrate specificity of Vipera lebetina venom phosphodiesterase]. PMID- 4290339 TI - [Ribonuclease activity of the liver and spleen during experimental mouse hepatitis caused by MHV-3 virus]. PMID- 4290340 TI - [Attempts at localization of zones of the central nervous system sensitive to ACTH in the "stretching syndrome"]. PMID- 4290341 TI - Normal and 5-bromodeoxyuridine-inhibited development of herpes simplex virus. An electron microscope study. PMID- 4290342 TI - Heterotrophic CO2 fixation by a bleached Euglena. PMID- 4290343 TI - Requirement of calcium ions for the cell fusion reaction of animal cells by HVJ. PMID- 4290344 TI - Preparation of cell suspensions from tissues using collagenase and hyaluronidase, especially for measuring the electrical charges of surface membranes of mammalian cells. PMID- 4290345 TI - Fine structure of a melanotic progonoma or retinal anlage tumor of the anterior fontanel. PMID- 4290346 TI - Virus biographies. II. Growth of herpes simplex virus in tissue culture. PMID- 4290347 TI - Electron microscopic observations on bronchial epithelium. 1. Annulate lamellae. PMID- 4290349 TI - Viral agents in gastrointestinal disease. PMID- 4290348 TI - Myocardial enzymes in plasmocid-poisoned rabbits. A correlative histochemical and biochemical study. PMID- 4290350 TI - Enterovirus infections of the central nervous system. The present and future of poliomyelitis. PMID- 4290351 TI - Respiratory disease and the adenoviruses. PMID- 4290352 TI - Clinical syndromes in children caused by respiratory infection. PMID- 4290353 TI - [The treatment of mammary cancer with cyclophosphamide. Clinical and therapeutic considerations]. PMID- 4290354 TI - [Hereditary sensory radicular neuropathy and its relation to other diseases]. PMID- 4290355 TI - [Pituitary and adrenal function under surgical stress in geriatric patients]. PMID- 4290356 TI - [Metabolism of glycogen. I. Biochemical aspects of glycogenosis]. PMID- 4290357 TI - [Lupic disease. Apropos of a curious case]. PMID- 4290358 TI - [Late solitary metastasis to the lung of a Wilms' tumor in a child]. PMID- 4290359 TI - Vasoconstriction induced by sympathetic stimulation during development of hypertension. PMID- 4290360 TI - Increased vascular response to angiotensin during ganglionic blockade. PMID- 4290361 TI - Response to angiotensin infusion before and after adrenalectomy in the rabbit. PMID- 4290362 TI - Insulin preservation of glucokinase activity in isolated perfused rat liver. PMID- 4290363 TI - Renin-aldosterone system in endotoxin shock in the dog. PMID- 4290364 TI - Mechanical activity of vascular smooth muscle under anoxia. PMID- 4290365 TI - Wilms' tumor: a summary of 25 years of experience before actinomycin-D. PMID- 4290366 TI - Precocious sexual development; roentgenographic aspects. PMID- 4290367 TI - Obstruction in cancer of the colon. PMID- 4290368 TI - In vitro neoplastic transformation of newborn hamster salivary-gland tissue by oncogenic DNA viruses. PMID- 4290369 TI - Eccrine sweat gland adenoma, clear cell type. A histochemical study. PMID- 4290370 TI - Optimum conditions for the reaction between uric and phosphotungstic acids in the presence of glycerol-silicate reagent, including a proposed modification of the Archibald method. PMID- 4290371 TI - Diabetic peripheral neuropathy. PMID- 4290372 TI - Diagnostic lymphography. PMID- 4290373 TI - [Differential diagnosis and treatment of trophoblastic tumor]. PMID- 4290374 TI - [Electron microscope findings in lung cancer]. PMID- 4290375 TI - [Case of diffuse lung cancer wrongly diagnosed as alveolar cell carcinoma]. PMID- 4290376 TI - Suppression of tumorous adrenal hyperfunction by aminoglutethimide. PMID- 4290378 TI - [Apropos of cancer of the liver during hemochromatosis]. PMID- 4290377 TI - Phospholipid changes during hepatic injury caused by carbon tetrachloride. PMID- 4290379 TI - [Cytochrome C oxydase]. PMID- 4290380 TI - [Nicotinic acid provision of the organism of otosclerosis patients and the possibility of its therapeutic application in the complex treatment of this disease]. PMID- 4290381 TI - Influence of mineralocorticoids and cations on the inotropic effect of angiotensin and norepinephrine in isolated cardiac muscle. PMID- 4290383 TI - [Studies on the antiviral action of hydrazine compounds. 3. Inhibitory activity in vivo and in vitro of the sodium salt of the isoniazid of metasulfonbenzaldehyde on vaccinia virus]. PMID- 4290382 TI - [Michaelis constants and maximun rate of turnover of pyruvate and TPP activated acetaldehyde with pyruvate decarboxylase and pyruvate oxydase]. PMID- 4290384 TI - [On the antipoliomyelitic activity of guanidine in vitro. XV. Inhibitory activity of BW 329.C.60 and 467.C.60 on the CPE and the multiplication of poliovirus I]. PMID- 4290385 TI - Cirrhosis and primary cancer of the liver. Comparative study in Tokyo and Cincinnati. PMID- 4290386 TI - Chemotherapy of germinal tumors. PMID- 4290387 TI - Comparative study of methods of administering mitomycin C. PMID- 4290388 TI - [Hemoperitoneum caused by ruptured subcapsular hepatoma, lobectomy and recovery]. PMID- 4290389 TI - Biological regulation of inorganic pyrophosphate-glucose phosphotransferase and glucose 6-phosphatase. Activation by triamcinolone, in vivo, in the presence of actinomycin D. PMID- 4290390 TI - [Studies on the metabolism of I-132 angiotensin II in experimental renal hypertension and its alteration by renal veno-portal anastomosis in dogs]. PMID- 4290391 TI - Enzyme histochemical studies on the hypothalamus of spontaneously hypertensive rats with special reference to that of rats subjected to various endocrine interferences. PMID- 4290392 TI - Prolonged venous catheterization as a cause of sepsis. PMID- 4290393 TI - Application of skin allergic test in the diagnosis of adenoviral infections in children. PMID- 4290394 TI - A case of temporal lobe epilepsy with some unusual features. PMID- 4290395 TI - [The role of age in malignant tumors of the jaw-face region]. PMID- 4290396 TI - The effect of partial portacaval transposition on the canine liver. PMID- 4290397 TI - Degeneration of the inner nuclear layer of the retina following lesions of the optic nerve. PMID- 4290398 TI - Endocrine function following treatment of pituitary adenoma. PMID- 4290399 TI - Electrophoretic studies on phosphatases from the pancreatic islets of obese hyperglycaemic mice. PMID- 4290400 TI - The effect of epinephrine on testosterone production. PMID- 4290401 TI - On the presence of precorticotrophin--a precursor of corticotrophin in various mammalian hypophyses. PMID- 4290402 TI - Stimulation of adrenocorticoidogenesis by precorticotrophin after activation. PMID- 4290403 TI - Effects of beta-1-24 synthetic corticotrophin on reproductive tract and kidneys of immature female mice. PMID- 4290404 TI - Enzymic hydrolysis of barley and other beta-glucans by a beta-(1--4)-glucan hydrolase. AB - 1. A barley glucan with 68% of beta-(1-->4)-linkages and 32% of beta-(1-->3) linkages was exhaustively hydrolysed with an Aspergillus niger beta-(1-->4) glucan 4-glucanohydrolase (EC 3.2.1.4) (Clarke & Stone, 1965b). The hydrolysis products were separated and estimated. 2. The lower-molecular-weight products were identified as: glucose, 1.4%; cellobiose, 11.9%; 3(2)-O-beta glucosylcellobiose, 45.0%; a tetrasaccharide(s), which was a substituted cellobiose, 16.4%. A series of unidentified higher-molecular-weight products (26.5%) were also found. 3. The identity of the products suggests that the A. niger beta-(1-->4)-glucan hydrolase hydrolyses beta-glucosidic linkages joining 4 O-substituted glucose residues. 4. When an enzyme fraction containing the beta-(1 ->4)-glucan hydrolase and an exo-beta-(1-->3)-glucan hydrolase was used, the same products were found, but the higher-molecular-weight products were observed to have only a transient existence in the hydrolysate and were virtually absent after prolonged incubation. It is suggested that these oligosaccharides are resistant to attack by beta-(1-->4)-glucan hydrolase but are partially hydrolysed by the exo-beta-(1-->3)-glucan hydrolase and therefore possess one or more (1- >3)-linked glucose residues at their non-reducing end. PMID- 4290405 TI - The effect of metabolic inhibitors on the development of respiration in anaerobically grown yeast. AB - 1. Iodoacetate and fluoride did not prevent the development of respiration in aerobically grown yeast. 2. The effect of dinitrophenol suggested that phosphorylation developed simultaneously with respiration in anaerobically grown yeast, but the effect of oligomycin suggested that the phosphorylation and oxidation were not tightly coupled. 3. Inhibitors of electron transport showed that both the respiratory peak and the subsequent respiration were cyanide sensitive, but the peak respiration was insensitive to antimycin. 4. Of the inhibitors of protein or RNA synthesis tested, only p-fluorophenylalanine inhibited the development of respiration. The results are not consistent with a new synthesis of mitochondria. 5. 2-Phenylethanol inhibited the development of respiration in anaerobically grown yeast and also yeast growth. Other inhibitors of DNA synthesis had no effect on the development of respiration. 6. The relevance of the results to mitochondrial morphogenesis is discussed. PMID- 4290406 TI - Chromatographic behaviour of rat-liver monophosphoinositide. AB - 1. Chromatography of rat-liver lipids on a column of silicic acid or a mixture of silicic acid and Hyflo Super-Cel, with chloroform-methanol mixtures, gave monophosphoinositide-containing fractions which were invariably contaminated by the presence of nitrogen-containing phospholipids. The behaviour of the inositide was extremely sensitive to column loading and the results with different batches of silicic acid were not reproducible. 2. However, when chromatography on an alumina column was used, the solvent system chloroform-methanol-water (23:23:4, by vol.) completely eluted the neutral lipids, choline-containing phospholipids and phosphatidylethanolamine. An increase of the water content of the solvent to 14% (by vol.) then led to the elution of the monophosphoinositide component, now free from nitrogen-containing phospholipids, but still contaminated by the presence of a phospholipid, which from its properties was taken to be polyglycerophosphatide. 3. Most of the polyglycerophosphatide could be removed from a rat-liver lipid extract by silicic acid chromatography with chloroform methanol (19:1, v/v). The other phospholipids were then eluted and applied to an alumina column, whereby a monophosphoinositide fraction of much greater purity was obtained. 4. Further purification of the monophosphoinositide was achieved by chromatography on a mixture of silicic acid and cellulose powder. The final product was virtually pure by thin-layer chromatography and gave the expected analysis for monophosphoinositide. PMID- 4290407 TI - Clearing-factor lipase in adipose tissue. Factors influencing the increase in enzyme activity produced on incubation of tissue from starved rats in vitro. AB - 1. Evidence is presented that the increase in clearing-factor lipase activity that occurs when adipose tissue from starved rats is incubated in a defined medium in vitro is due to an increase in the total enzyme content of the system. It is shown that the clearing-factor lipase activity rises to reach a plateau level where, it is suggested, rates of enzyme synthesis and of enzyme destruction become balanced. 2. The presence of heparin in the incubation medium results in the extraction of part of the clearing-factor lipase originally present in the adipose tissue and this could provide the stimulus for the increase in total enzyme content. 3. Glucose is required in the incubation medium at a very low concentration. It can be replaced by fructose, but not by pyruvic acid, lactic acid, glyceric acid or dihydroxyacetone. 4. Adrenaline and corticotrophin inhibit the increase in enzyme activity when they are present in the incubation medium. 5. The high clearing-factor lipase activity associated with adipose tissue of fed rats is decreased by 50% within 3hr. of the injection of puromycin. PMID- 4290408 TI - Studies in rapidly labelled ribonucleic acid in cell fractions and in tumour tissues. AB - 1. Twenty minutes after injection of [(3)H]orotic acid into rats the rapidly labelled RNA from the liver is mainly associated with the nuclear fraction and little with the ribosomal cytoplasmic fraction. 2. The thermal denaturation of RNA from the fractions was not as reversible as that of the RNA extracted from whole liver. 3. Rapidly labelled RNA is synthesized by cells from a transplantable hepatoma when incubated in the presence of [(3)H]uridine and, after extraction and centrifugation, the label is present in three main fractions: one which sediments to the bottom of a gradient and is associated with DNA, a second which sediments to the heavy side of the 28s RNA, and a third which has a peak of activity between 28s RNA and 18s RNA and is associated with DNA. 4. After labelling and extraction of the RNA from Ehrlich ascites cells the distribution of radioactive components is similar to that of the material from the hepatoma cells. 5. The difference between the tumour cells and liver is due to some extent to the method of homogenizing the tissues and the nature of the components is discussed. PMID- 4290409 TI - Rapidly labelled ribonucleic acid from rat liver. Studies in the attachment to ribosomes and stimulation of the incorporation of amino acids into polypeptides in cell-free systems. AB - 1. Rapidly labelled RNA from rat liver, either as a complex with DNA (m-RNA-DNA) or with ribosomal RNA (m-RNA-RNA) binds to ribosomes in the polysome region. No binding could be demonstrated with ribosomal RNA or native DNA from Bacillus subtilis. 2. With ribosomes from rat liver, Escherichia coli or hepatoma the m RNA-DNA stimulated incorporation of amino acids with rat-liver ribosomes only, whereas the m-RNA-RNA complex was effective with ribosomes from E. coli or the hepatoma. 3. Polyuridylic acid was effective as messenger RNA with all three ribosomes but much greater stimulation was obtained with ribosomes from E. coli and the hepatoma. 4. The degree of incorporation of phenylalanine with polyuridylic acid and ribosomes from a hepatoma was decreased by about 50% when ribosomal RNA was present. PMID- 4290410 TI - Unusual group of tumours among schoolgirls. PMID- 4290411 TI - The isolation of nuclei from rat liver during aminoazo dye carcinogenesis. PMID- 4290412 TI - Clostridial sepsis. PMID- 4290413 TI - Treatment of choriocarcinoma. PMID- 4290414 TI - [Contribution to the demonstration of herpesvirus in encephalitis]. PMID- 4290415 TI - [Contribution to the clinic and pathology of the cylindroma in the oro-maxillary region]. PMID- 4290416 TI - [Participation of phenols in the fermentative oxidation of NAD-H2]. PMID- 4290417 TI - [Atypical case--bladder cancer presenting anemia and aphasia as chief symptoms, but without jaundice or pain]. PMID- 4290418 TI - [Therapy of nervous system diseases with ACTH and experimental studies on its mechanism of action, with special reference to the nonadrenal effects of ACTH]. PMID- 4290419 TI - Chromosome studies of human brain tumors. PMID- 4290420 TI - Abrupt withdrawal of adrenal corticosteroids in patients with rheumatoid arthritis: the clinical observations of twelve cases. PMID- 4290421 TI - Diurnal variation in adrenal cortical function. PMID- 4290422 TI - Insecticidal compounds. Effects on replication of vaccinia and polio viruses in human chang-strain liver cells. PMID- 4290423 TI - Etiology of the acute infectious respiratory diseases. With specific reference to the rhinoviruses. PMID- 4290424 TI - Control of acute viral respiratory diseases. Effects of infection, vaccines, and chemotherapy. PMID- 4290425 TI - [Bilateral isolated ptosis in adenovirus infection]. PMID- 4290426 TI - Interferon synthesis in x-irradiated animals. I. Depression of circulating interferon in C3H mice after whole-body irradiation. PMID- 4290427 TI - Histological changes in interrenal tissue of the goldfish, Carassius auratus, following x-irradiation. PMID- 4290428 TI - [Morphologic changes in Entamoeba histolytica under the effect of some acridine derivatives and chloroquine in culture]. PMID- 4290429 TI - [The profile of carbohydrate metabolism in the neoplastic process and in some rapid growth systems]. PMID- 4290430 TI - [The lipids of cerebral white matter during autolysis and in anemic softening]. PMID- 4290431 TI - Histochemical demonstration of cytochrome oxidase activity in the lens. PMID- 4290432 TI - [Current treatment of the principal bullous skin diseases]. PMID- 4290433 TI - [On the origin of hidradenoma of the eyelids]. PMID- 4290434 TI - [On some properties of fructose-1,6-diphosphatase of rat kidney]. PMID- 4290435 TI - Peripheral neuropathy of sensorimotor type associated with malignant disease. PMID- 4290436 TI - Mumps and enteroviral meningitis in Toronto, 1966. AB - Of 52 children admitted to hospital for apparently typical mumps meningitis in 1966, 50 had their cerebrospinal fluid (CSF) examined. In only 17 was the mumps virus isolated from the CSF. Mumps antihemagglutinin conversions or increments were detected in 32 subjects including 10 whose CSF yielded virus. Antibody conversions were found in 16 patients and fourfold increments in another nine whose serum pairs were collected only one to four days apart. Initial sera from 20 patients were obtained three days or less after the onset of meningitis. Antibody increments were frequently noted about one day after defervescence and clinical improvement. Interferon was detected in CSF from two of eight patients, both of whom yielded virus. Enteroviruses were isolated from CSF and/or feces in seven of 15 cases of aseptic meningitis which occurred between July and October. Six patients including three virus excretors showed enteroviral neutralizing antibody increments during convalescence. The dominant enteroviral serotype was coxsackievirus A9. PMID- 4290437 TI - Reconstitution of cytochrome C oxidase from a copper-depleted enzyme and Cu. PMID- 4290438 TI - Vitamin E deficiency in the rat. 3. The relationship of nicotinamide adenine dinucleotide to respiratory decline. PMID- 4290439 TI - Mucopolysaccharide sulfation in chick embryo cartilage. I. Properties of the sulfation system. PMID- 4290440 TI - Purification and characterization of poliovirus-induced infectious double stranded ribonucleic acid. PMID- 4290441 TI - Enzymes of plasma membranes of liver. PMID- 4290442 TI - Acyl carrier protein. IX. Acyl carrier protein hydrolase. PMID- 4290443 TI - Tryptophan as intermediate in dehydrogenase action. 3. Evidence for complete cycle of hydrogen transfer between substrate and tryptophanyl residues in rabbit muscle lactate dehydrogenase. PMID- 4290444 TI - The isolation and metabolism of brown fat cells. PMID- 4290445 TI - A long chain terpenyl pyrophosphate synthetase from Micrococcus lysodeikticus. PMID- 4290446 TI - Studies on the renal glomerular basement membrane. Nature of the carbohydrate units and their attachment to the peptide portion. PMID- 4290447 TI - The inhibition by phlorizin of kidney microsomal inorganic pyrophosphate-glucose phosphotransferase and glucose 6-phosphatase. PMID- 4290448 TI - Studies on cytochrome c peroxidase. IX. The reaction of ferrimyoglobin with hydroperoxides and a comparison of peroxide-induced compounds of ferrimyoglobin and cytochrome c peroxidase. PMID- 4290449 TI - [Effects of anesthetic and surgical stress on pituitary-adrenocortical function. 1. Their effects on ACTH in blood]. PMID- 4290451 TI - [Adenomeloblastoma as a diagnostic problem]. PMID- 4290450 TI - [Effects of anesthesia and surgical stress on pituitary-adrenocortical function. 2. Effect on the concentration of free 17-OHCS in the blood]. PMID- 4290452 TI - Antiviral substances in plants of the mint family (labiatae). II. Nontannin polyphenol of Melissa officinalis. PMID- 4290453 TI - Polyoma virus-induced "complement-fixing antigen" in tumors and infected cells and detected by immunofluorescence. PMID- 4290454 TI - Infrequent C-F antibody response in mice with adenovirus type 12 tumors. PMID- 4290455 TI - Effect of pituitary and gonadal hormones on Friend Virus Disease in mice. PMID- 4290456 TI - SV-40 virus growth and cytopathogenicity in a serial rabbit kidney cell line. PMID- 4290457 TI - Vitamin D deficiency in adult quail and chickens and effects of estrogen and testosterone treatments. PMID- 4290458 TI - Inapparent herpes simplex virus infection in inoculated rabbits. PMID- 4290459 TI - Recovery of an adenovirus from a feral rodent Peromyscus maniculatus. PMID- 4290460 TI - Effect of thyroxine administration on enzymes associated with glucose metabolism in the liver. PMID- 4290461 TI - Mitigated teratogenicity of thio-TEPA in goldthioglucose obese mice. PMID- 4290462 TI - Transformation of bovine cells in vitro by polyoma virus, and the properties of the transformed cells. PMID- 4290464 TI - Increased susceptibility of Down's syndrome fibroblasts to transformation by SV40. PMID- 4290463 TI - Effect of a low sodium diet on aldosterone-stimulating activity of angiotensin II in dogs. PMID- 4290465 TI - Yellow bone marrow as adipose tissue. PMID- 4290466 TI - Studies on the inability of rhinovirus to survive and replicate in the intestinal tract of volunteers. PMID- 4290467 TI - Immunologic response in hamsters to homologous tumor antigens measured in vivo and in vitro. PMID- 4290468 TI - [Studies on the multiplication of SV40 in tissue cultures]. PMID- 4290469 TI - [Isolation and identification of Cl. perfringens from the intestinal contents of healthy individuals]. PMID- 4290470 TI - [Some data in favor of the enzymatic nature of Cl. perfringens and oedematiens toxins]. PMID- 4290471 TI - Virological findings during the smallpox outbreak in Stockholm in 1963. PMID- 4290472 TI - Studies on oral enzymes. IV. Fractionation and characterization of various hydrolytic enzymes in human saliva. PMID- 4290473 TI - Effect of angiotensin on renal function in the rat. PMID- 4290474 TI - Carcinoid-islet cell tumors of the duodenum. PMID- 4290475 TI - C-glycosylflavonoids. The chemistry of aspalathin. AB - 1. The isolation of aspalathin, the principal phenolic constituent in the leaves of Aspalathus linearis, is described and its properties are discussed. 2. The compound has been identified as 3'-C-beta-d-glucopyranosyl-2',3,4,4',6' pentahydroxydihydrochalcone by the preparation and analysis of various derivatives, by photochemical oxidation to 2,3-dihydroiso-orientin and by nuclear magnetic-resonance studies. PMID- 4290476 TI - [Destruction of the alpha isomer of NAD in the rat liver]. PMID- 4290477 TI - [On the inactivation of the MHV-3 hepatitis virus by various mouse tissues and by intestine of various animal species]. PMID- 4290478 TI - [Serological study of the distribution or adenovirus among the population living on the shores of Lake Trasimeno]. PMID- 4290479 TI - Acute conjunctivitis among Cairo children. Decrease in K.W. and gonococcal infections and increase in bacteriologically negative cases. PMID- 4290480 TI - Epithelial cytoplasmic pseudo inclusions in conjunctivitis. PMID- 4290481 TI - Phosphoserine phosphatase of vertebrates. PMID- 4290482 TI - [On the delimitation of Bartter's syndrome. A case of angiotensin-resistant vessels, increased plasma renin, increased aldosterone secretion and anovulatory menstrual cycle]. PMID- 4290483 TI - Ethanol-induced alterations of norepinephrine metabolism in man. PMID- 4290484 TI - Liver parenchymal cell injury. V. Relationships between patterns of chloromethane C 14 incorporation into constituents of liver in vivo and cellular injury. PMID- 4290485 TI - [Effect of fluorocarbon on the pathogenic activity of MHV-3 virus]. PMID- 4290486 TI - [Studies on the possible mechanism of imipramine action on O2 consumption in rats]. PMID- 4290487 TI - [Histochemical studies of various mixed tumors of the parotid gland]. PMID- 4290488 TI - [Effect of the age factor on the development of malignant lymphomas and hepatomas in Swiss mice treated with urethane (ethyl carbamate)]. PMID- 4290489 TI - [The effects of polymyxin, diprazin (promethasine) and dimedrol (benadryl) on the ascorbic acid content in tissues of certain organs in albino rats]. PMID- 4290490 TI - [Distribution of serum neutralizing antibodies against enterovirus in a remote area of Hokkaido]. PMID- 4290491 TI - Bronchial asthma in infants and children due to food and inhalant allergies. PMID- 4290492 TI - Bicarbonate and the binding of iron to transferrin. PMID- 4290493 TI - Antibody responses of rhesus (Macaca mulatta) monkeys experimentally infected with coxsackieviruses of group B and group A, type 9. II. Heterotypic antibody responses to echoviruses, polioviruses and reovirus type 1. PMID- 4290494 TI - Antibody and gland studies in cortisone and ACTH-injected birds. PMID- 4290495 TI - A serologic study of herpesvirus hominis strains by microneutralization tests. PMID- 4290496 TI - Laryngeal haematomas due to coagulopathies. PMID- 4290497 TI - Granular cell myoblastoma of the larynx. PMID- 4290498 TI - Transplantability of primary tumors of RPL12 virus-induced lymphoid leukosis. PMID- 4290499 TI - Induction of tumors in adult hamsters with simian virus 40. PMID- 4290500 TI - Diphosphopyridine nucleotide in the treatment of schizophrenia. PMID- 4290502 TI - A cutaneous clue to mammary carcinoma. Paget's disease of the nipple. PMID- 4290501 TI - Surveillance of respiratory virus infections among Alaskan Eskimo children. PMID- 4290503 TI - Gas gangrene following an adrenaline-in-oil injection into the left thigh with survival. PMID- 4290504 TI - Effects of nonsuppressible insulin-like activity and insulin on glucose oxidation and lipolysis in the isolated adipose cell. PMID- 4290505 TI - Vulvar fibroadenoma from aberrant breast tissue. Report of 2 cases. PMID- 4290506 TI - Hemifacial spasm. PMID- 4290507 TI - The chemistry of pseudouridine. PMID- 4290508 TI - Calcifying mucinous adenocarcinoma of the stomach. PMID- 4290509 TI - Studies on the relationship between adeno-associated virus type I (AAV-1) and adenoviruses. I. Replication of AAV-1 in certain cell cultures and its effect on helper adenovirus. PMID- 4290510 TI - Studies of three variants of Mengo encephalomyelitis virus. IV. Affinities for mouse tissues in vitro and in vivo. PMID- 4290511 TI - Fragmentation of the nucleus in Rous sarcoma virus-infected chick embryo cells. PMID- 4290512 TI - [A modified method for rapid identification of tick-borne and Japanese encephalitis viruses in the hemagglutination-inhibition test]. PMID- 4290513 TI - [The experimental action of interferon on enteric viruses]. PMID- 4290514 TI - [A study of natural changes in susceptibility to viruses of the established I-96 cell line and cloned subcultures]. PMID- 4290515 TI - [An outbreak of illnesses due to respiratory syncytial virus]. PMID- 4290516 TI - [The antiviral action of ethylenimines]. PMID- 4290517 TI - Enzymologic approach to the diagnosis of death by drowning. Preliminary report. PMID- 4290518 TI - The bacteria Mima-herellea. Isolation and clinical significance in a general hospital. PMID- 4290519 TI - Isolation of cytomegalovirus from tissues of condyloma acuminatum. PMID- 4290520 TI - Cytomegalic inclusion disease. The fetal disorder. PMID- 4290521 TI - Congenital spongioblastoma of the pons. PMID- 4290522 TI - Concentration of viruses on aluminum and calcium salts. PMID- 4290523 TI - Studies of infantile diarrhea in Karachi, Pakistan. II. Multiple virus isolations from rectal swabs. PMID- 4290524 TI - The uptake of enteroviruses by the New Zealand marine blue mussel Mytilus edulis aoteanus. PMID- 4290525 TI - Histological studies of the monkey neurovirulence of group B arboviruses. 3. Relative virulence of selected viruses. PMID- 4290526 TI - Effect of ischemia on conduction of nerve fibers of varying diameters. PMID- 4290527 TI - Effect of interferon on the production and action of viral RNA polymerase. PMID- 4290528 TI - Piericidin A: a new inhibitor of mitochondrial electron transport. PMID- 4290529 TI - Evidence for uracil nucleotide-rich segments in the RNA molecule of the virus BAI strain A (avian myeloblastosis). PMID- 4290530 TI - Observations on the actin content of the rabbit myofibril. AB - 1. On extraction of whole muscle by the procedure of Hasselbach & Schneider (1951), the amount of actin that passes into solution seems to account for little more than 10% of the protein content of the myofibrils. 2. Extraction of isolated myofibrils with suitable media that allow identification and estimation of dissolved proteins seems to give about the same yield of actin (10-13% of the total). 3. A comparatively large residue of myofibrillar components remains after extraction. The amount of actin present in the residue can be only hypothetical. PMID- 4290531 TI - The polyphosphoinositides and other lipids of peripheral nerves. AB - 1. A detailed lipid analysis of the peripheral nerves of the crab (claw, leg), lobster (claw, leg), cow (splenic), hen, rabbit, sheep and monkey (sciatic) is presented. 2. The so-called ;myelinic lipids', cholesterol, sphingomyelin, ethanolamine plasmalogen and phosphatidylserine, occurred in the highest proportion in the lipids of vertebrate myelinated nerves, whereas the percentage of lecithin was greatest in the lipids of non-myelinated nerve fibres of both vertebrates and invertebrates. 3. Triphosphoinositide was found in all nerves examined and its concentration in the extracted lipids supports the concept that it is predominantly localized in the myelin sheath. 4. In crustacean nerve 12-14% of the phospholipids was in the form of alkyl ether phospholipids, which in the lobster were approximately half choline-containing and half ethanolamine containing. PMID- 4290532 TI - Abolition by actinomycin D pretreatment in vivo of the stimulating effect of serum proteins on the protein synthesis of Yoshida ascites hepatoma in vitro. PMID- 4290533 TI - The kinetics and mechanism of liver alcohol dehydrogenase with primary and secondary alcohols as substrates. AB - 1. The activity of liver alcohol dehydrogenase with propan-2-ol and butan-2-ol has been confirmed. The activity with the corresponding ketones is small. Initial rate parameters are reported for the oxidation of these secondary alcohols, and of propan-1-ol and 2-methylpropan-1-ol, and for the reduction of propionaldehyde and 2-methylpropionaldehyde. Substrate inhibition with primary alcohols is also described. 2. The requirements of the Theorell-Chance mechanism are satisfied by the data for all the primary alcohols and aldehydes, but not by the data for the secondary alcohols. A mechanism that provides for dissociation of either coenzyme or substrate from the reactive ternary complex is described, and shown to account for the initial-rate data for both primary and secondary alcohols, and for isotope-exchange results for the former. With primary alcohols, the rapid rate of reaction of the ternary complex, and its small steady-state concentration, result in conformity of initial-rate data to the requirements of the Theorell-Chance mechanisms. With secondary alcohols, the ternary complex reacts more slowly, its steady-state concentration is greater, and therefore dissociation of coenzyme from it is rate-limiting with non-saturating coenzyme concentrations. 3. Substrate inhibition with large concentrations of primary alcohols is attributed to the formation of an abortive complex of enzyme, NADH and alcohol from which NADH dissociates more slowly than from the enzyme-NADH complex. The initial-rate equation is derived for the complete mechanism, which includes a binary enzyme alcohol complex and alternative pathways for formation of the reactive ternary complex. This mechanism would also provide, under suitable conditions, for substrate activation or substrate inhibition in a two-substrate reaction, according to the relative rates of reaction through the two pathways. PMID- 4290534 TI - The inhibition of ribonucleic acid polymerase by acridines. AB - 1. The aminoacridines, proflavine (3,6-diaminoacridine) and 9-aminoacridine, and a hydrogenated derivative, 9-amino-1,2,3,4-tetrahydroacridine, were shown to inhibit in vitro the DNA-primed RNA polymerase of Escherichia coli. The inhibition is strong with both proflavine and 9-aminoacridine, but weak with 9 amino-1,2,3,4-tetrahydroacridine. 2. The extent to which the three acridines bind to calf-thymus DNA in the enzyme medium was studied spectrophotometrically. The extent of binding decreases in the order: proflavine, 9-aminoacridine, 9-amino 1,2,3,4-tetrahydroacridine. Some evidence was also obtained for interaction between the nucleoside triphosphate substrates and proflavine or 9-aminoacridine; no such interaction was detectable with 9-amino-1,2,3,4-tetrahydroacridine. 3. Although the amount of acridine bound to DNA increases with increasing inhibition, a stage is reached where an increase in acridine concentration still causes an increase in inhibition, with practically no increase in the amount bound to DNA. 4. Plots of reciprocal rates against the reciprocal of DNA concentration were linear and had a common intercept when proflavine or 9 aminoacridine was present. Similar relations were obtained when the reciprocal concentration of nucleoside triphosphates was plotted. The observations are interpreted kinetically in terms of a competitive inhibition of the enzyme by proflavine or 9-aminoacridine and of a kinetic role for the DNA analogous to ;activation'. 5. This suggests that inhibitory acridine molecules can occupy the sites on the RNA polymerase that are specific for binding the nucleoside triphosphate substrate or the bases of the DNA, when these become accessible during the copying process. PMID- 4290535 TI - Gradient centrifugation in colloidal silica-polysaccharide media. PMID- 4290536 TI - Preparation and properties of a cell-free system from rat skin that catalyzes sterol biosynthesis. AB - Homogenates of epidermis from rat skin were centrifuged at 10,000 X g for 20 min. The supernatant fraction ("whole homogenate") catalyzed the demethylation of lanosterol (C(30)) to yield C(27)-sterols. The rate of reaction was measured by the rate of release of (14)CO(2) from the 4-methyl group of lanosterol. Conditions for maximal rates of demethylation were established. Addition of increasing amounts of washed microsomes to a constant amount of substrate resulted in additional release of (14)CO(2), but the release was not proportional to the amount of microsomes. Incubation with increasing amounts of microsomes treated with Triton WR-1339 yielded a proportional rate of release of (14)CO(2). The Triton-treated microsomes were frozen and stored without loss of activity. The rate of formation of (14)CO(2) was constant up to 1 hr of incubation with both Triton-treated microsomes and whole homogenate, for which the K(m) for lanosterol was 5.0 and 3.0 X 10(-5) M, respectively. Other 4-gem-dimethyl sterols were competitive inhibitors, K(i)', 2.0 and 5.5 X 10(-5) M. The enzyme system was inhibited by arsenite. 24,25-Dihydrolanosterol, 24,25-dihydrolanostenone, and squalene were demethylated by the homogenate. The whole homogenate catalyzed the incorporation of mevalonic acid, but not acetic acid, into squalene and sterols. The enzymatic properties of the sterol synthetic system from skin resemble those of similar preparations from rat liver. PMID- 4290537 TI - Gas--liquid chromatography of silylated mixtures from lipolysis of triglycerides containing unusual fatty acyl groups. AB - A convenient and rapid procedure involving methylation, silylation, and temperature-programmed gas-liquid chromatography (GLC) is described for analyzing unfractionated products from the hydrolysis of triglycerides with pancreatic lipase. The conditions employed for GLC were selected to provide maximum and rapid separation of silylated monoglycerides in which the acyl moieties differ in chain length or degree of substitution with oxygen-containing functional groups. Derivatives differing only in the number of double bonds present were not separated. In the GLC curves obtained, peaks representing methyl esters are generally readily distinguishable from those of other components. Therefore, the extent of lipolysis and the composition (with respect to chain length and substitution of acyl groups) of monoglycerides formed are determined simultaneously. The accuracy of the new method was demonstrated with standard mixtures and by comparison of results for several lipolysis products with data obtained by conventional procedures. PMID- 4290538 TI - Electron microscopic study on the effect of the oxidation of ultrathin sections of Bacillus cereus and Bacillus megaterium. PMID- 4290539 TI - Recurrent herpes in the rabbit and man. AB - Herpesvirus was present in secretory glands and frequently in tears of rabbits with recurrent herpetic keratitis even in the absence of corneal lesions. In normal people, herpesvirus could be cultured from saliva and tears. Chronic virus multiplication in structures such as the lacrimal and salivary glands, rather than latency, may cause recurrent herpetic disease. PMID- 4290540 TI - Adenovirus tumorigenesis: role of the viral genome in determining tumor morphology. AB - Adenovirus type 12 transforms the fibroblastic BHK21 (baby hamster kidney) cell line into rounded or cuboidal cells that give rise in hamsters to undifferentiated small cell sarcomas indistinguishable from those induced in newborn hamsters by inoculation of the virus itself. In contrast. cells from this line transformed by polyoma virus retain their fibroblastic morphology and induce fibrosarcomas in hamsters. This suggests that the morphology of tumors induced by the adenovirus-transformed cells from this line may be determined by the viral genome and that such mechanism may also explain the remarkably uniform microscopic appearance which seems to characterize tumors induced in hamsters by direct inoculation of adenovirus type 12. PMID- 4290541 TI - An antibody to oxytocin. PMID- 4290542 TI - Mucinous adenocarcinoma of the urachus in women. PMID- 4290543 TI - Comparative lipid composition of psittacosis and trachoma agents. PMID- 4290544 TI - Induction of interferon by the Bour strain of trachoma in HeLa 229 cells. PMID- 4290545 TI - Prediction of the age of maximum puberal growth in body height. PMID- 4290546 TI - Adrenocorticotrophic hormone and erythropoietin. PMID- 4290547 TI - The relation of cirrhosis of the liver to renal hypertension. A review of 639 autopsied cases. PMID- 4290548 TI - A specific sucrose phosphatase from plant tissues. AB - 1. A phosphatase that hydrolyses sucrose phosphate (phosphorylated at the 6 position of fructose) was isolated from sugar-cane stem and carrot roots. With partially purified preparations fructose 6-phosphate, glucose 6-phosphate, fructose 1-phosphate, glucose 1-phosphate and fructose 1,6-diphosphate are hydrolysed at between 0 and 2% of the rate for sucrose phosphate. 2. The activity of the enzyme is increased fourfold by the addition of Mg(2+) ions and inhibited by EDTA, fluoride, inorganic phosphate, pyrophosphate, Ca(2+) and Mn(2+) ions. Sucrose (50mm) reduces activity by 60%. 3. The enzyme exhibits maximum activity between pH6.4 and 6.7. The Michaelis constant for sucrose phosphate is between 0.13 and 0.17mm. 4. At least some of the specific phosphatase is associated with particles having the sedimentation properties of mitochondria. 5. A similar phosphatase appears to be present in several other plant species. PMID- 4290549 TI - The glycerol teichoic acid from the cell wall of Bacillus stearothermophilus B65. AB - 1. A glycerol teichoic acid has been extracted from cell walls of Bacillus stearothermophilus B65 and its structure examined. 2. Trichloroacetic acid extractable teichoic acid accounted for 68% of the total cell-wall phosphorus and residual material could be hydrolysed to a mixture of products including those characteristic of glycerol teichoic acids. 3. The extracted polymer is composed of glycerol, phosphoric acid, d-glucose and d-alanine. 4. Hydrolysis of the polymer with alkali gave glycerol, 1-O-alpha-d-glucopyranosylglycerol and its monophosphates, glycerol mono- and di-phosphate, as well as traces of a glucosyldiglycerol triphosphate and a glucosylglycerol diphosphate. 5. The teichoic acid is a polymer of 18 or 19 glycerol phosphate units having alpha-d glucopyranosyl residues attached to position 1 of 14 or 15 of the glycerol residues. 6. The glycerol residues are joined by phosphodiester linkages involving positions 2 and 3 in each glycerol. 7. d-Alanine is in ester linkage to the hydroxyl group at position 6 of approximately half of the glucose residues. 8. One in every 13 or 12 polymer molecules bears a phosphomonoester group on position 3 of a glucose residue, the possible significance of which in linkage of the polymer to other wall constituents is discussed. PMID- 4290550 TI - The components of an alpha-glycerophosphate cycle and their relation to oxidative metabolism in the lens. AB - 1. The concentration of ATP in a lens brei is maintained when the brei is incubated in oxygen with alpha-glycerophosphate. Lack of alpha-glycerophosphate or incubation in nitrogen causes the concentration to decrease. alpha Glycerophosphate has some effect under anaerobic conditions but this is not sufficient to account for the maintenance in oxygen. 2. Manometric experiments show that alpha-glycerophosphate enhances the respiration of lens preparations. This respiration can be further increased by the addition of ADP and is abolished by cyanide and antimycin. The inference from these experiments is that a mitochondrial system able to oxidize alpha-glycerophosphate is present, i.e. the particulate half of the alpha-glycerophosphate cycle. 3. More than the calculated proportion of NADH is used when limiting amounts of dihydroxyacetone phosphate are added to lens tissue in spectrophotometric experiments. Dihydroxyacetone phosphate is therefore regenerated and an alpha-glycerophosphate cycle is operative. 4. A preparation of a particulate alpha-glycerophosphate dehydrogenase that takes up oxygen with methylene blue as electron acceptor is described. 5. Methods for obtaining mitochondria from lens are compared, and a useful extraction medium is defined. 6. Mitochondria with activities of the same order of magnitude as those obtained from liver, with alpha-glycerophosphate and glutamate as substrates, are prepared from epithelium detached from the capsule; some respiratory control is observed. PMID- 4290551 TI - A study of the reaction catalysed by the liver branching enzyme. AB - The mechanism of action of liver branching enzyme has been studied by using as substrate two polysaccharides in which the non-reducing ends had been labelled by incubation with phosphorylase and a trace amount of [(14)C]glucose 1-phosphate. After these polysaccharides had been treated with branching enzyme, their structure was analysed by periodate oxidation, by degradation with phosphorylase and amylo-(1-->6)-glucosidase and by degradation with pullulanase. All the results indicate that the branching enzyme catalyses the transfer from (1-->4)- to (1-->6)-linkage of a chain of glucose units, the minimum length of which is six glucose units. A maltodextrin containing 16 glucose units was not acted on by the branching enzyme. PMID- 4290552 TI - Some rate constants for the phenazine methosulphate-catalysed oxidation of reduced nicotinamide-adenine dinucleotide. AB - Kinetic measurements have been made on the phenazine methosulphate-catalysed oxidation of NADH(2) and the effects of cyanide, EDTA, Fe(2+), catalase and an unidentified mitochondrial factor on this reaction are examined. Chemical equations are formulated and values of the rate constants are determined. The data suggest the existence of an unreactive form of the reduced phenazine methosulphate; the stability and possible nature of such a compound are discussed. PMID- 4290554 TI - Metabolism of continuously fed 14C-labeled N-hydroxy-N-2-fluorenylacetamide at various intervals: effect of pituitary hormones. PMID- 4290553 TI - Studies on nucleolar RNA fractions of the Walker and Novikoff tumors. PMID- 4290555 TI - Some urea cycle enzymes and amino acyl-RNA synthetases of rat hepatomas. PMID- 4290556 TI - Antigenicity of a virus-induced murine sarcoma (Moloney). PMID- 4290557 TI - Virus-like particles in 3-methylcholanthrene-induced primary and transplanted sarcomas of germ-free rodents. PMID- 4290558 TI - Biological properties of a transplantable islet-cell tumor of the golden hamster. II. Insulin content of the tumor and some metabolic characteristics of the tumor bearing animals. PMID- 4290560 TI - Multiple harvest technic for production of parainfluenza and measles hemagglutinating antigens. PMID- 4290559 TI - Microscopic studies of the effect of epinephrine on the isolated fat cells of the rat epididymal fat pads. PMID- 4290561 TI - Mouse-protective properties of Bordetella pertussis serotypes in passive tests. AB - In a passive protection procedure in which the ed(50) values of Bordetella pertussis antisera were determined, groups of mice were given graded intraperitoneal doses of serum, followed the next day by intracerebral challenge with 100,000 organisms. Antiserum produced with B. pertussis culture 5373, serotype 1.3, protected mice against challenge with culture 18-323, serotype 1.2.3, as effectively as did an antiserum produced with a serotype 1.2.3 culture. When two groups of mice similarly treated with pertussis immune serum were challenged with culture 353Z (serotype 1) and 18-323, respectively, much lower ed(50) values were obtained with the animals challenged with 353Z. Passive protection tests with adsorbed antiserum gave equivocal results, suggesting that some of the adsorbing antigen remained in the serum and interfered with the tests. There was no evidence that serotype is related to protection. PMID- 4290562 TI - Formation and operation of the histidine-degrading pathway in Pseudomonas aeruginosa. AB - Histidine ammonia lyase (histidase), urocanase, and the capacity to degrade formiminoglutamate, which are respectively involved in steps I, II, and IV in the catabolism of histidine, were induced during growth of Pseudomonas aeruginosa on histidine or urocanate, and were formed gratuitously in the presence of dihydro urocanate. Urocanase-deficient bacteria formed enzymes I and IV constitutively; presumably they accumulate enough urocanate from the breakdown of endogenous histidine to induce formation of the pathway. Urocanate did not satisfy the histidine requirement of a histidine auxotroph, indicating that it probably acted as an inducer without being converted to histidine. The results imply that urocanate is the physiological inducer of the histidine-degrading enzymes in P. aeruginosa. Enzymes of the pathway were extremely sensitive to catabolite repression; enzymes I and II, but not IV, were coordinately repressed. Our results suggest a specific involvement of nitrogenous metabolites in the repression. Mutant bacteria with altered sensitivity to repression were obtained. The molecular weight of partially purified histidase was estimated at 210,000 by sucrose gradient centrifugation. Its K(m) for histidine was 2 x 10(-3)m in tris(hydroxymethyl)aminomethane chloride buffer. Sigmoid saturation curves were obtained in pyrophosphate buffer, indicating that the enzyme might have multiple binding sites for histidine. Under certain conditions, histidase appeared to be partially inactive in vivo. These findings suggest that some sort of allosteric interaction involving histidase may play a role in governing the operation of the pathway of histidine catabolism. PMID- 4290563 TI - In vitro demonstration of humoral and cell-bound immunity against common specific transplantation atigen(s) of adenovirus 12-induced mouse and hamster tumors. AB - A colony inhibition (CI) technique was used to demonstrate in vitro tumor specific antigenicity common for neoplasms induced by the adenovirus type 12. Immunization of mice against syngeneic mouse adeno 12 tumor cells evoked immunity demonstrable against other adeno 12 neoplasms of mice and of hamster as well. The immunity was detected as antibody activity in the sera of specifically immunized mice and as a similar activity of the lymph node cells of these animals. The finding in transplantation experiments that infection with adenovirus types 12 and 7 induces an isograft immunity against adeno 12 tumors was confirmed by CI tests on the sera of virus-infected mice. The probable identity of the antigen detected by the CI technique and the tumor-specific transplantation antigen is discussed. PMID- 4290564 TI - The action of lysozyme on bacterial electron transport systems. PMID- 4290565 TI - Persistent non-cytocidal infection of BHK 21 cells by human parainfluenza type 2 virus. PMID- 4290566 TI - Experimental brain tumors, with a report of those induced in dogs by Rous sarcoma virus. PMID- 4290567 TI - Calcified soft-tissue mass in the medial aspect of the thigh. PMID- 4290568 TI - [On the procedure of treating chronic suppurative otitis media with polymyxin]. PMID- 4290569 TI - [Comparative assay by morphological indices of various methods of treating experimental esophageal burns]. PMID- 4290570 TI - [Data on the diagnosis and pathomechanism of osteomalacia]. PMID- 4290571 TI - Diagnosis of hypopituitarism in childhood. PMID- 4290572 TI - Differential diagnosis of children with short stature not associated with metabolic, chromosomal, or gross nervous system defects. PMID- 4290574 TI - [The significance of the thyroid gland in the reaction of adrenal cortex in response to ACTH]. PMID- 4290573 TI - Effect of treatment on the metabolism of tryptophan in childhood epilepsy. PMID- 4290575 TI - [Histochemical characteristics of some energy metabolism enzymes in the process of experimental silicotic connective tissue formation]. PMID- 4290577 TI - Bacteriocin produced by Bordetella pertussis. AB - Of the 24 strains of Bordetella pertussis examined, 2 produced bacteriocins that inhibited the growth of all but 2 other strains of this species. The two strains producing the bacteriocin and the two resistant strains were rough, whereas all susceptible strains were smooth. The bacteriocin was not active on the B. parapertussis or B. bronchiseptica strains tested. These bacteriocins appeared to be protein in nature, since they were heat-labile and partially inactivated by trypsin. They were antigenic but the neutralizing antibodies did not precipitate the antigens. Absorption of the antiserum with homologous cell suspensions removed the agglutinating, but not the neutralizing, antibody. PMID- 4290576 TI - Histochemical studies of chondrocyte function in the cartilage of the mandibular codyle of the rat. PMID- 4290578 TI - Genetic mapping of mutations affecting phosphoglucose isomerase and fructose diphosphatase in Escherichia coli. AB - The loci on the Escherichia coli genome of mutations affecting phosphoglucose isomerase (pgi) and fructose diphosphatase (fdp) have been determined by conjugation and transduction experiments, chiefly three-factor crosses. The loci for these two constitutive enzymes of central intermediary metabolism lie in the same region of the chromosome, but they are not cotransducible. The order of some markers in this region of the chromosome is arg(ACFH) metA pgi malB uvrA fdp pyrB thr. PMID- 4290579 TI - Studies of androgens in patients with adrenocortical tumors. PMID- 4290580 TI - Pituitary-adrenocortical studies in a patient with Cushing's syndrome induced by thymoma. PMID- 4290581 TI - Effect of angiotensin II on immunoreactive insulin. PMID- 4290582 TI - Inhibition of renin by heparin. PMID- 4290584 TI - Experimental infectious canine hepatitis. II. Effect of cortisone acetate on experimental infection in the guinea-pig. PMID- 4290583 TI - Blood cholesterol and hydrocortisone production in man: quantitative aspects of the utilization of circulating cholesterol by the adrenals at rest and under adrenocorticotropin stimulation. AB - A kinetic study of the conversion of blood cholesterol into hydrocortisone was carried out in two patients through prolonged infusions of cholesterol-4-(14)C. The following points appear to be established by our observations:1) The infused tracer behaved metabolically like endogenous cholesterol; it could therefore serve as a means of labeling plasma cholesterol for investigating its utilization by the adrenal cortex.2) At rest, about 80% of hydrocortisone derived from plasma cholesterol, the other 20% thus being synthesized in situ from acetate and other unlabeled precursors.3) Under ACTH stimulation the participation of plasma cholesterol in the synthesis of hydrocortisone was the same as at rest; the conversion of plasma cholesterol into hydrocortisone was thus proportional to the production of glucocorticosteroids by the adrenal glands.4) The specific activities of hydrocortisone allowed us to trace its adrenal precursors including adrenal cholesterol. The kinetics of the replacement of adrenal cholesterol by plasma cholesterol underlined the functional heterogeneity of the former. The experimental data were compatible with the following model: A fraction of plasma cholesterol entering the adrenal cell is immediately available for metabolism and conversion into steroid hormones, and another fraction turns over slowly, representing some form of storage. PMID- 4290585 TI - The pressor response to serum and exogenous renin in rats. PMID- 4290586 TI - Purification of ferritin-conjugated antibody by DEAE-cellulose chromatography. PMID- 4290587 TI - Simple syndactyly and its surgical repair. PMID- 4290588 TI - Light and electron microscopic studies of the guinea pig cytomegalovirus. PMID- 4290589 TI - DNA polymerases from mammalian cells. PMID- 4290590 TI - [The dynamics of establishment and destruction of the contacts between cells of the Zaidel ascites hepatoma in tissue culture]. PMID- 4290591 TI - Metabolism of palmitaldehyde-1-14C in the rat brain. PMID- 4290592 TI - Inosine 5'-phosphate dehydrogenase. Site of inhibition by guanosine 5'-phosphate and of inactivation by 6-chloro- and 6-mercaptopurine ribonucleoside 5' phosphates. PMID- 4290593 TI - The heterogeneous distribution of mitochondrial enzymes in normal rat liver. PMID- 4290594 TI - Solid-phase peptide synthesis of [L-alanine 3-L-isoleucine 5]-angiotensin II. PMID- 4290595 TI - An electron spin resonance study of copper(II)-peptide complexes in the liquid state. PMID- 4290596 TI - Selective inhibition of aminoacyl ribonucleic acid synthetases by aminoalkyl adenylates. PMID- 4290597 TI - Structure of the cell wall of Staphylococcus aureus, strain Copenhagen. VII. Mode of action of the bacteriolytic peptidase from Myxobacter and the isolation of intact cell wall polysaccharides. PMID- 4290599 TI - A cutaneous syndrome associated with islet-cell carcinoma of the pancreas. PMID- 4290598 TI - Adnexal skin tumours in Nigeria. PMID- 4290600 TI - Reduction in renal vascular responses to angiotensin and norepinephrine during carotid sinus stimulation. PMID- 4290601 TI - The breakdown of embryonic cartilage and bone cultivated in the presence of complement-sufficient antiserum. 2. Biochemical changes and the role of the lysosomal system. PMID- 4290602 TI - A sero-epidemiological study of adenovirus infections. PMID- 4290603 TI - Clinicopathologic conference. Weakness, jaundice, and oliguria. Resume of a case. PMID- 4290604 TI - Nature of the non-haem iron in ferredoxin and rubredoxin. PMID- 4290605 TI - Protein-disulphide reductase activity in yeast. PMID- 4290606 TI - Infection of thymidine kinase-deficient BHK cells with polyoma virus. PMID- 4290608 TI - Comparative cytopathology of rinderpest and bovine parainfluenza 3 viruses in cell cultures. PMID- 4290607 TI - Electron spin resonance examination of charge transfer complexes of polycyclic carcinogens and nucleic acid bases. PMID- 4290609 TI - Herpes simplex virus particles in the nerves of rabbit corneas after epithelial inoculation. PMID- 4290610 TI - Effect of actinomycin D and halogenated deoxyuridines on the replication of Bittner virus in vitro. PMID- 4290611 TI - Viral inhibitory activity of polyvinylpyrrolidone. PMID- 4290612 TI - Absolute configuration of the prostaglandins. PMID- 4290613 TI - Cell metabolism during melanophore activity. PMID- 4290614 TI - [The effects on the prostate in animals of combined overloading of ACTH and liver damage]. PMID- 4290615 TI - [Toxic effect of parathion on the organism of albino rats)]. PMID- 4290616 TI - The Guillain-Barre syndrome associated with acquired cytomegalovirus infection. PMID- 4290617 TI - [Selective ion-exchange sorption of ristomycin on cation exchange resins]. PMID- 4290618 TI - [Stability of florimycin (viomycin) in aqueous solutions]. PMID- 4290619 TI - [Cochleo-vestibular deficiency syndrome following retrogasserian neurotomy]. PMID- 4290620 TI - [Quantitative analysis of urinary 11-dedoxy-17-ketosteroids by means of gas chromatography]. PMID- 4290621 TI - Myxovirus dissemination by air. AB - Myxoviruses including 150 strains of parainfluenza 1, 15 of parainfluenza 3 and five of influenza B virus were isolated from nasopharyngeal secretions obtained from 300 children less than 3 years of age who developed acute laryngotracheobronchitis during the preceding 48 hours. The patients were examined between October 1966 and January 1967, the peak monthly rate of virus isolation (67%) occurring during January. Parainfluenza 1 virus was isolated from air obtained in the vicinity of one of 30 children whose nasopharyngeal secretions yielded this agent. Samples comprising 150 litres of air were collected for virus assay by placing an Andersen sampler about 60 cm. from the child's face inside an oxygen tent which surrounded the patient. These findings confirm previous observations that parainfluenza 1 virus is the dominant agent associated with acute laryngotracheobronchitis in children in Toronto, and they show that this virus is disseminated in the air. PMID- 4290622 TI - Mechanism of action of streptonigrin in leukemic cells. PMID- 4290623 TI - Utilization of L-methionine and S-adenosyl-L-methionine for methylation of soluble RNA by mouse liver and hepatoma extracts. PMID- 4290624 TI - Observations on thymectomy and carcinogenesis. PMID- 4290626 TI - The reaction of specific antibody with 2-acetylaminofluorene fixed in liver cells. PMID- 4290625 TI - Biochemical effects of formycin, an adenosine analog. PMID- 4290627 TI - Alkaline ribonuclease and ribonuclease inhibitor in nuclear and nucleolar preparations from normal and neoplastic tissues. PMID- 4290628 TI - Control of lipid metabolism in hepatomas: insensitivity of rate of fatty acid and cholesterol synthesis by mouse hepatoma BW7756 to fasting and to feedback control. PMID- 4290629 TI - Screening data from the Cancer Chemotherapy National Service Center Screening Laboratories. XLI. Plant extracts. PMID- 4290630 TI - [Studies on the relationship between lactation and corticoids, with special reference to urinary 11-deoxy-17 KGS and 11-oxy-17 KGS]. PMID- 4290631 TI - [Studies on the pituitary ACTH secretory capacity in children using 11-beta hydroxylase inhibitor (Metopirone). 2. Diagnostic value in pituitary dwarfism in children]. PMID- 4290632 TI - [Effects of various hormones on serum lipids with reference to the fatty acid transport pattern]. PMID- 4290633 TI - Genetic studies of carcinogenesis in mice. PMID- 4290634 TI - Inhibitory effects of Sendai virus on Friend virus leukemia in mice. PMID- 4290635 TI - Effect of certain drugs on perfused human placenta. VII. Serotonin versus angiotensin-II. PMID- 4290636 TI - [Therapeutic policy and its effects in various stages of chronic nephritis]. PMID- 4290637 TI - [Adrenal cortex function test using a synthetic ACTH containing 24 amino acids: a rapid ACTH test]. PMID- 4290638 TI - Transient intermediates in the radiolysis of hyaluronic acid. PMID- 4290640 TI - Cytopathology of Mengovirus infection. II. Proliferation of membranous cisternae. PMID- 4290641 TI - Biophysical properties of poliovirus particles irradiated with ultraviolet light. PMID- 4290642 TI - Granular cell myoblastoma of the breast. PMID- 4290639 TI - Cytopathology of Mengovirus infection. I. Relationship between cellular disintegration and virulence. PMID- 4290643 TI - The low-temperature luminescent spectra of adenine and its derivatives. PMID- 4290644 TI - [Cellular infection by adenovirus in HeLa cell cultures studied by means of the fluorescent antibody technic]. PMID- 4290645 TI - [Action of angiotensin on the urinary secretion of electrolytes in the normotensive dog]. PMID- 4290646 TI - [Enzymatic levels in the kidney of rats fed a phosphate deficient diet]. PMID- 4290647 TI - [Pancreatic circulation in the dog studied with NaI-131 diffusion curves. 13. Influence of hypertensin]. PMID- 4290648 TI - Use of drug combinations for treatment of adeno-virus infections of the eye in tissue culture. PMID- 4290649 TI - Further advances on the effect of t-fluorodesoxyuridine on adeno-virus infection in tissue culture. PMID- 4290650 TI - [The effect of vincaleukoblastine (Velbe) on the glycolysis of tumor cells]. PMID- 4290652 TI - Ultrastructure of Cocal, Indiana, and New Jersey serotypes of vesicular stomatitis virus. PMID- 4290651 TI - The reaction of reduced cytochrome C oxidase with oxygen. PMID- 4290653 TI - [Study of certain properties of actomyosin in the presence of adenosine triphosphate with the aid of electron microscopy]. PMID- 4290654 TI - A testicular tumor of specialized gonadal stroma. PMID- 4290655 TI - Granular-cell myoblastoma of the larynx. PMID- 4290656 TI - Cryosurgical management of glomus jugulare tumors. PMID- 4290657 TI - Adenocarcinoma of the larynx. PMID- 4290658 TI - [Cytomegalic inclusion disease]. PMID- 4290659 TI - Tumor specific antigens in viral neoplasms and in unrelated virus infected tumors. PMID- 4290660 TI - Studies with the complement fixing antigen induced by polyoma virus. PMID- 4290661 TI - SV40 transformation of human diploid cells. A parallel study of viral and karyologic parameters. PMID- 4290662 TI - Virological studies on chromosome damage of HeLa cells induced by myxoviruses. PMID- 4290663 TI - Interference with rous sarcoma virus focus formation by a mycoplasmalike factor present in human cell cultures. PMID- 4290664 TI - Production of interferon by human leukocytes in vitro. PMID- 4290665 TI - Nonresponsiveness of L cells to the induction of interferon. PMID- 4290666 TI - Enhancement and inhibition by anionic polymers of plaque development by a variant of Mengo encephalomyelitis virus. PMID- 4290667 TI - Studies of false positive serological tests for syphilis following smallpox vaccination. PMID- 4290668 TI - The lipids of human diploid cell strain WI-38. PMID- 4290669 TI - [Comparison of 2 methods for the determination of leukocyte phosphatase]. PMID- 4290670 TI - Destructon of micro quantities of steroids on silica gel as shown by repeated thin-layer chromatography. PMID- 4290671 TI - [The significance of rhinoviruses in calf diseases]. PMID- 4290672 TI - [ECSO viruses and diseases of piglets]. PMID- 4290673 TI - [A parainfluenza virus in hens' eggs]. PMID- 4290674 TI - Effect of corticosteroid administration on the adrenocorticotropic response to electrical stimulation of the hypothalamus in the dog. PMID- 4290675 TI - Thermal behaviour of silica and its application to dental investments. 3. The effect of grain size distribution upon the thermal expansion of quartz investments. PMID- 4290676 TI - [Wilms' tumor. Clinico-radiological observations on 5 cases seen in the last 3 years at the Clinica Pediatrica of the Universita di Messina]. PMID- 4290677 TI - [The effect of ions and gases on the hydrate membrane of yeast alcohol dehydrogenase as studied by polarography]. PMID- 4290678 TI - Adrenal function in cockerels. PMID- 4290679 TI - Determination of iodide clearance and exit rate constants in incubated thyroid lobes. PMID- 4290680 TI - Neonatal androgen or estrogen treatment and the adrenal cortica response to stress in adult rats. PMID- 4290681 TI - [Response of adrenal steroids to the administration of various drugs]. PMID- 4290682 TI - [Studies on urinary 17-ketogenic steroids (17-KGS) fractions in children, using sodium metaperiodate oxidation, with special reference to urinary 17-KGS, 17-KS and pregnanetriol in normal children]. PMID- 4290683 TI - The behavior of cells before and after virus-induced malignant transformation. PMID- 4290684 TI - Fatal complications following use of potassium perchlorate in thyrotoxicosis. Report of two cases and a review of the literature. PMID- 4290685 TI - Grand rounds at the Washington University School of Medicine. II. Protoplasts and pyelonephritis. PMID- 4290686 TI - Androstenedione and its conversion to plasma testosterone in congenital adrenal hyperplasia. AB - The plasma concentration, production rate, and conversion ratio of androstenedione and testosterone were studied in seven children with congenital adrenal hyperplasia (CAH) of the 21-hydroxylase type. Plasma androstenedione and testosterone measured by double isotope derivative assay and estimated blood production rates were manyfold increased in the untreated state, markedly suppressed with glucocorticoid, and increased after the administration of ACTH. The metabolic clearance rate when corrected for body size and the conversion ratio of androstenedione to testosterone were similar to previously determined values in normal adults. Consideration of the androgen concentrations and conversion ratios indicates that in children with CAH, 76% of the plasma testosterone in prepubertal females and 36% in males are derived from peripheral conversion of blood androstenedione. The calculated amount of testosterone unaccounted for by peripheral conversion is similar to normal prepubertal values. This approach indicates that virilization in these children results from increased levels of testosterone but that the major source in CAH of this potent androgen is androstenedione secreted by the adrenal cortex. PMID- 4290688 TI - [Histoenzymic study on the early closure of the epiphysis]. PMID- 4290687 TI - Metabolism of vitamin D3-3H in human subjects: distribution in blood, bile, feces, and urine. AB - Vitamin D(3)-(3)H has been administered intravenously to seven normal subjects, three patients with biliary fistulas, and four patients with cirrhosis. Plasma D(3)-(3)H half-times normally ranged from 20 to 30 hours. in vivo evidence that a metabolic transformation of vitamin D occurs was obtained, and a polar biologically active vitamin D metabolite was isolated from plasma. Urinary radioactivity averaged 2.4% of the administered dose for the 48-hour period after infusion, and all the excreted radioactivity represented chemically altered metabolites of vitamin D. The metabolites in urine were mainly water-soluble, with 26% in conjugated form. From 3 to 6% of the injected radioactivity was excreted in the bile of subjects with T-tube drainage and 5% in the feces of patients having no T-tube. The pattern of fecal and biliary radioactivity suggested that the passage of vitamin D and its metabolites from bile into the intestine represents an essential stage for the fecal excretion of vitamin D metabolites in man. Abnormally slow plasma disappearance of vitamin D(3)-(3)H in patients with cirrhosis was associated with a significant decrease in the quantity and rate of glucuronide metabolite excretion in the urine. PMID- 4290690 TI - [Experiences with synovioma of the knee]. PMID- 4290689 TI - [Studies on neurography of the peripheral nerves. 1. Experimental study on neurography of the peripheral nerves. 2. Tissue fluid flow from the peripheral nerves to the nerve trunk. 3. Experimental study on the etiological mechanism of traumatic brachial plexus paralysis by neurography. 4. Clinical application of neurography of the peripheral nerves]. PMID- 4290691 TI - Tumors in rhesus monkeys inoculated at birth with homologous cells converted in vitro by Rous sarcoma virus, Schmidt-Ruppin strain. PMID- 4290692 TI - Ultrastructure of gliomas induced in hamsters with Rous sarcoma virus. PMID- 4290693 TI - [Two cases of nasopharyngeal angiofibroma with special reference to treatment with sex hormones]. PMID- 4290694 TI - Cerebral gigantism: endocrinological and clinical observations of six patients including a congenital giant, concordant monozygotic twins, and a child who acheived adult gigantic size. PMID- 4290695 TI - The Chediak-Higashi syndrome: electrophysiological and electron microscopic observations on the peripheral neuropathy. PMID- 4290696 TI - Induction of herpes simplex virus lesions on rabbit lip mucosa. PMID- 4290697 TI - [Biochemical studies on the phenotype of cancer cells]. PMID- 4290698 TI - [Angiotensin and gastric secretion]. PMID- 4290699 TI - Rapid detection of hyperglycemic rebound in insulinoma surgery. PMID- 4290700 TI - Cavitary bronchiolar carcinoma with an intracavitary aspergilloma. PMID- 4290701 TI - NADH-Dependent coupled enzyme assay for urease and other ammonia-producing systems. PMID- 4290702 TI - Double-blind study of the effect of corticotropin treatment in multiple sclerosis. PMID- 4290703 TI - [Transport of alpha-aminoisobutyric acid in peritoneal macrophages of rats in the presence of silica crystals]. PMID- 4290704 TI - [Glucose-6-phosphatase and fructose-1,6-diphosphatase activity in Opuntia ficus indica]. PMID- 4290705 TI - [Phosphoprotein phosphatase in the skeletal muscle of chick embryo]. PMID- 4290706 TI - [Decrease in the activity of 1-serine hydrolyase (deaminating), 1-threonine hydrolyase (deaminating) phosphoserine phosphohydrolase and 1 serine:tetrahydrofolate 10-hydroxymethyltransferase of the liver in rats treated with ethionine]. PMID- 4290707 TI - [Metabolites of skeletal muscles in thyroid-fed rats]. PMID- 4290708 TI - A cultural psychiatric study of El-Zar cult in U.A.R. PMID- 4290709 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. 13. Structure and function of submitochondrial particles completely resolved with respect to coupling factor. PMID- 4290710 TI - On the nature of the changes induced in Escherichia coli by osmotic shock. PMID- 4290711 TI - The incomplete hydroxylation of individual prolyl residues in collagen. PMID- 4290712 TI - Stimulation of the catecholamine output of the isolated, perfused adrenal gland of the dog by angiotensin and bradykinin. PMID- 4290713 TI - Influence of ouabain on the formation of corticosterone in the rat adrenal gland. PMID- 4290714 TI - Intraperitoneal haemorrhage from primary hepatic carcinoma. PMID- 4290715 TI - Hypoglycaemia resulting from insulin secreting tumours of the pancreas. PMID- 4290716 TI - The effect of interferon on SV-40 T antigen production in SV-40-transformed cells. PMID- 4290717 TI - Observations on the assay of infectious viral ribonucleic acid: effects of DMSO and DEAE-dextran. PMID- 4290718 TI - Surgical complications of adrenal steroid therapy. PMID- 4290719 TI - [On a phosphoprotein phosphatase of the skeletal muscle tissue of the chick embryo]. PMID- 4290721 TI - Studies on the metabolism of the protozoa. The molecular structure of the reserve polysaccharide from Astasia ocellata. AB - 1. The flagellate Astasia ocellata synthesizes as reserve carbohydrate a water insoluble polysaccharide (paramylon) containing chains of beta-(1-->3)-linked d glucose residues. 2. The average chain length, determined by methylation analysis, is about 43, and the minimum degree of polymerization from periodate oxidation data is 50-55. Most of the molecules are therefore essentially linear. PMID- 4290720 TI - The biosynthesis of glycerides by mitochondria from rat liver. The requirement for a soluble protein. AB - 1. The synthesis of glycerides from l-3-glycerophosphate and palmitic acid by mitochondrial preparations from rat liver was shown to be stimulated markedly by a soluble factor from the supernatant fraction of the liver. 2. That the soluble factor was a protein was indicated by its inactivation after treatment with papain and after boiling for 3min. at 100 degrees , its precipitation by ammonium sulphate and its behaviour on Sephadex G-200. The soluble factor was purified by ammonium sulphate fractionation and gel filtration. 3. Bovine serum albumin and lipoprotein fractions from rat and human serum also stimulated glyceride biosynthesis but the stimulations were one-twentieth to one-third of that obtained with the soluble factor. 4. The function of the soluble factor could not be explained by assuming a leakage of acyl-CoA synthetase, phosphatidate phosphatase or diglyceride acyltransferase from the mitochondria into the supernatant during preparation of the mitochondrial fraction. 5. Palmitic acid, in the presence of the soluble factor and optimum amounts of ATP and CoA, was a more effective substrate than palmitoyl-CoA or palmitoylcarnitine for the biosynthesis of glycerides by mitochondria. PMID- 4290722 TI - The phosphatidylinositol kinase of rat brain. AB - 1. The presence of a phosphatidylinositol kinase in homogenates of adult rat brain was shown by using labelled ATP or labelled phosphatidylinositol. 2. The kinase was activated by Mg(2+) or Mn(2+) and inhibited by Ca(2+), Cu(2+), K(+), Na(+) and F(-). 3. The detergents sodium deoxycholate, Cutscum and Triton X-100 markedly stimulated the reaction; sodium taurocholate, Tween-20 and cetyltrimethyl-ammonium bromide were less effective. 4. The activity of the enzyme was dependent on SH groups. 5. The subcellular distribution of the kinase in brain resembled that of Na(+)-plus-K(+)-stimulated adenosine triphosphatase and 5'-nucleotidase. PMID- 4290723 TI - Degos' acanthoma (acanthome a cellules claires). A report of five cases with particular reference to the histochemistry. PMID- 4290724 TI - Turban tumour. PMID- 4290725 TI - Herpes simplex encephalitis: two fatal cases. AB - The clinical and pathological features of the first two reported cases of herpes simplex encephalitis occurring in Saskatchewan are presented. The clinical history of an acute onset, an early organic mental syndrome followed by coma, neurologic disturbances, rapid progression and death suggests the diagnosis. The acute, diffuse, inflammatory process with predominant involvement of the temporal lobes of the cerebral hemispheres and the presence of intranuclear inclusions in nerve and glial cells are illustrated. The viral particles were found in electron micrographs from the brain tissue of both patients. The definitive diagnosis was established by the isolation, from postmortem brain tissue, of the herpes simplex virus, which was grown in tissue culture and shown to be pathogenic in suckling mice. PMID- 4290726 TI - Cushing's syndrome due to an ACTH-producing carcinoma of the thyroid. PMID- 4290727 TI - Purine N-oxides. XIX. On the oncogenic N-oxide derivatives of guanine and xanthine and a nononcogenic isomer of xanthine N-oxide. PMID- 4290729 TI - [The two-photon character of a sensitized photodecay of methyl iodide, as detected by means of electron-spin resonance]. PMID- 4290728 TI - [Femoral head infarction after glucocorticoid treatment]. PMID- 4290730 TI - [Urinary gonadotropin in gynecology with special reference to adrenocortical function]. PMID- 4290732 TI - Hypotriglyceridemic effect of corticotropin in man. PMID- 4290731 TI - Releasing factors in human hypothalamic and neurohypophysial extracts. PMID- 4290733 TI - Abnormal diurnal variation of plasma cortisol in patients with renovascular hypertension. PMID- 4290734 TI - Estrogen metabolism in the human. I. Studies in the male using estrone-6,7-3H, with special reference to estrone production rate determinations, the origin of certain urinary estrogen conjugates, and the use of a new mathematical model. PMID- 4290735 TI - Estrogen metabolism in the human. II. Studies in the male using estradiol-17-beta 6,7-3H. PMID- 4290736 TI - Recurrent Cushing's syndrome associated with aldosterone deficiency. PMID- 4290738 TI - The effect of hypophysectomy and corticotrophin on the renal sensitivity to antidiuretic hormone. PMID- 4290737 TI - Biochemical composition of human testicular fluid collected post mortem. PMID- 4290739 TI - Prevention of implantation in rats by I.C.I. 46,474: role of histamine. PMID- 4290740 TI - Purification and properties of poliovirus double-stranded ribonucleic acid. PMID- 4290741 TI - Preparation and properties of some methylated polycytidylic acids. PMID- 4290742 TI - What hyperbaric medicine has to offer the industrial physician. PMID- 4290743 TI - [Plasmatic angiotensinase activity in subjects with hepatic diseases of various types]. PMID- 4290744 TI - Encephalitis due to herpes simplex in a patient with treated carcinoma of the uterus. Speculations about herpes simplex as a cause of carcinomatous encephalitis. PMID- 4290745 TI - [The functional state of the adrenal cortex in children with infectious hepatitis]. PMID- 4290746 TI - Effect of potassium on adrenal aldosterone production in rats. PMID- 4290747 TI - Effects of extrahypothalamic dexamethasone implants on the pituitary-adrenal system. PMID- 4290749 TI - Familial cirrhosis with hepatoma. PMID- 4290748 TI - Inhibition of gastric mucous secretion by ACTH. An experimental study. PMID- 4290750 TI - Systems analysis in the study of homeostasis. With special reference to cortisol secretion. PMID- 4290751 TI - Gas chromatographic analysis of oxidation products of adrenal corticosteroids. PMID- 4290752 TI - Detection of nanogram quantities of vitamin D by gas-liquid chromatography. PMID- 4290753 TI - The mechanism of action of UDPG-dehydrogenase. PMID- 4290754 TI - Isolation and characterization of dinucleoside tetra- and tri-phosphates formed in the presence of lysyl-sRNA synthetase. PMID- 4290755 TI - [Influence of ascorbic acid on viral cytopathogenic activity in tissue culture. II. Study of the effect of ascorbic acid on the cytopathogenic activity of type 1 poliomyelitis virus (Brushilde)]. PMID- 4290756 TI - Prediction of axillary nodal metastases from the morphology of primary mammary carcinomas. Guide to operative therapy. PMID- 4290758 TI - [4 cases of the mucous-epithelial tumor (tumor mucoepidermalis) in the oral cavity]. PMID- 4290759 TI - [Clinical studies of the effectiveness of hypertensin under conditions of anesthesia and shock]. PMID- 4290760 TI - [Suppression of synthesis of smallpox vaccine virus by histone]. PMID- 4290761 TI - Cell transformation by viruses as illustrated by the response of human and hamster renal cells to Simian virus 40. PMID- 4290762 TI - Primary aldosteronism with unusual secretory pattern. PMID- 4290763 TI - Quantitation of lactate dehydrogenase of developing molar teeth of the mouse. PMID- 4290764 TI - The tolbutamide tolerance texxt in the evaluation of childhood hypoglycemia. PMID- 4290765 TI - Intestinal cytochrome response with repair of iron deficiency. PMID- 4290766 TI - [Granular cell myoblastoma of the perianal region. (Report of a case)]. PMID- 4290767 TI - [Properties of R-1CA cell lines obtained from kidney cells of Cercopithecus aethiops cultured in vitro]. PMID- 4290768 TI - [Attempts to isolate viruses from chronic hepatitis]. PMID- 4290769 TI - Reduced diphosphopyridine nucleotide oscillations in cell-free extracts from beef heart. PMID- 4290770 TI - Aromatic acyl phosphates as substrates of acyl phosphatase. PMID- 4290771 TI - The relation of structural and catalytic protein in the mitochondrial electron transfer chain. PMID- 4290772 TI - [Effect of the adrenocorticotropic hormone (ACTH) skeletal muscles]. PMID- 4290773 TI - [Histochemical study of nerve ganglia of the pancreas]. PMID- 4290774 TI - [Inactivation of angiotensin by total blood and hemolyzed blood of normal and hypertensive subjects]. PMID- 4290775 TI - The infective agent in carp pox. PMID- 4290776 TI - [Incidence of hepatoma in French fisheries]. PMID- 4290777 TI - [Influenza of ducks. Influenza anatum]. PMID- 4290778 TI - [Infectious anemia of horses. Questions and answers on infectious anemia of horses]. PMID- 4290779 TI - Electron microscopy and classification of the virus of viral haemorrhagic septicaemia of rainbow trout. PMID- 4290781 TI - Inhibition by cortisol of ACTH release from anterior pituitary tissue in vitro. PMID- 4290780 TI - Response of isolated liver to endotoxin. PMID- 4290782 TI - Stimulation of adrenal activity by the administration of corticosterone to rats chronically treated with amphenone or methapyrapone. PMID- 4290783 TI - [Unilateral exophthalmos caused by acute orbital myositic]. PMID- 4290784 TI - [The diagnostic value of vestibular galvanic stimulation in certain otoneurologic syndromes]. PMID- 4290785 TI - Lymphographic studies related to the problem of metastatic spread from carcinoma of the female genital tract. PMID- 4290786 TI - A histochemical investigation of the concept of placental insufficiency. PMID- 4290787 TI - A Krukenberg tumour of the uterine cervix. PMID- 4290788 TI - Roentgenography of the diaphragmatic and retrosternal lymphatics by intraperitoneal injection of contrast material. PMID- 4290789 TI - [The pressure response to angiotensin and to noradrenaline in normal pregnancy and in the gestosic syndrome]. PMID- 4290790 TI - [Further observations on the cortisonic and aldosterone potentiation of the action of angiotensin in man]. PMID- 4290791 TI - The challenge to man of the neoplastic cell. PMID- 4290792 TI - Adenovirus endocarditis in mice. AB - Viral endocarditis developed in 24 percent of 50 newborn mice 6 to 8 days after intraperitoneal inoculation with murine adenovirus. Typical adenovirus intranuclear inclusions were seen in heart-valve lesions, and high titers of virus were recovered from heart tissue. Furthermore, adenovirions were directly visualized by electron microscopy within endothelial cells and fibroblasts of the heart valves. PMID- 4290793 TI - The effect of pregnancy on the clinical course of sarcoma of the soft somatic tissues. PMID- 4290794 TI - [Contributions to the study of antigenic relationships of Bordetella pertussis with Bordetella parapertussis]. PMID- 4290795 TI - [Contribution to the study of the antigenic structure of Cl. perfringens. I. Unusual serological behavior of a strain of Cl. perfringens]. PMID- 4290796 TI - [Contribution to the study of the antigenic structure of Cl. perfringens. II. Phase variation in Cl. Perfringens]. PMID- 4290797 TI - Studies on nuclear proteins. II. Quantitative distribution of histone fractions in various tissues. PMID- 4290798 TI - "Free" sialic acid in ovine submaxillary gland. PMID- 4290799 TI - A rapid technique for distinguishing enzymatically active proteins in the cell"envelope" of Escherichia coli B. PMID- 4290800 TI - [On the inactivating action in vitro of some ketoaldehyde derivatives on encephalomyocarditis (EMC) virus and aphthous (FMD) virus]. PMID- 4290801 TI - [Cytochemical research on experimental malignant hemopathies. Identification of cytoplasmic RNA in pathological cells of Friend's murine leukemia]. PMID- 4290802 TI - Experimental studies on dust elimination from lungs. V. Effect of sulphuric acid aerosol inhalations on quartz dust elimination from lungs of rabbits in course of a year. PMID- 4290803 TI - Radiographic appearances in chromolymphadenography. PMID- 4290804 TI - Repeated infections with respiratory syncytial virus. PMID- 4290805 TI - Characterization of hamster antibody reacting with papovavirus SV40 tumor antigen. PMID- 4290806 TI - Adoptive immunity to intracellular infection. PMID- 4290807 TI - [Apropos of a case of virilizing thecoma]. PMID- 4290808 TI - [The 1965-1966 influenza season and the results of laboratory studies]. PMID- 4290810 TI - Stabilization of catalase-ammonia complex in frozen solution. PMID- 4290809 TI - [Food poisonings caused by Cl. perfringens]. PMID- 4290811 TI - Composition and 32P turnover of phospholipids of rat adipose tissue. PMID- 4290812 TI - Cytomegalo virus--mononucleosis. Isolation of the virus and demonstration of subclinical infections after fresh blood transfusion in connection with open heart surgery. PMID- 4290813 TI - [Skeletal age and somatic maturity]. PMID- 4290814 TI - Demonstration of precorticotrophin in blood. PMID- 4290815 TI - Studies on extracellular phosphatase in Actinomycetes. PMID- 4290816 TI - Nervous elements in nephroblastoma. PMID- 4290817 TI - [Incompletely developed teeth. Treatment]. PMID- 4290818 TI - [Studies on the effects of combined use of polymyxin B]. PMID- 4290819 TI - Reversal of the enzyme profiles of muscle fibres in fast and slow muscles by cross-innervation. PMID- 4290820 TI - Myelinogenesis in the rat brain. PMID- 4290821 TI - The remote effects of cancer on the nervous system. PMID- 4290822 TI - Herpetic encephalitis. PMID- 4290823 TI - Acute viral infections of the nervous system. PMID- 4290824 TI - A fluorometric routine method for urinary unconjugated 11-hydroxycorticosteroids in adrenocortical hypofunction. PMID- 4290825 TI - A study of some acid hydrolases in the liver of the larval and adult lamprey. PMID- 4290826 TI - Intratympanic surgical treatment of frey's syndrome. PMID- 4290827 TI - An agar cell-suspension plaque assay for isolated viral RNA. PMID- 4290828 TI - ATP formation during enzymatic decomposition of coenzyme B12. PMID- 4290829 TI - [Changes in the activity of certain aortic enzymes in experimental atherosclerosis]. PMID- 4290830 TI - Characteristics of a newborn runt disease induced by neonatal infection with an oncolytic strain of reovirus type 3 (REO3MH). I. Pathological investigations in rats and mice. PMID- 4290831 TI - Characteristics of a newborn runt disease induced by neonatal infection with an oncolytic strain of reovirus type 3 (REO3MH). II. Immunological aspects of the disease in mice. PMID- 4290833 TI - Infection by Rous sarcoma virus of various chick embryo tissues cultured on reconstituted collagen membranes. PMID- 4290832 TI - Fatal intraperitoneal infection with Clostridium welchii Type A in passively immunised guinea-pigs. The effect on vascular permeability. PMID- 4290834 TI - Granular-cell myoblastoma of the breast. PMID- 4290835 TI - Salivary tumours: a clinicopathological study and follow-up of 156 cases. PMID- 4290837 TI - Cancer of the lung among nonsmokers. Special reference to histologic patterns. PMID- 4290836 TI - The angiotensin infusion test and peripheral venous renin activity. AB - Forty hypertensive patients were studied to examine the assumption that the angiotensin pressor dose reflects endogenous renin activity. Peripheral renin activity was assayed by the method of Boucher et al.(4) Sensitivity to the infusion of synthetic angiotensin II was determined as suggested by Kaplan and Silah.(1)Sixteen patients with essential hypertension with normal renal angiography required 3.8 ng. angiotensin/kg./min. to raise the diastolic pressure 20 mm. Hg. All but one were sensitive to angiotensin infusion of less than 5 ng./kg./min. Renin activity was normal in all except in one sensitive subject. Angiotensin infusion response and mean renin activity in 13 patients with essential hypertension with abnormal renal angiography were similar to that of the first group. The pressor dose in 11 renovascular hypertensives was 9.8 ng./kg./min. All but three had elevated plasma renin activity.OUR RESULTS SUGGEST THAT: (1) the angiotensin infusion test is suitable for differentiating patients with true renovascular hypertension from those with essential hypertension with or without associated renal artery disease; (2) the angiotensin pressor dose correlates with the level of peripheral venous renin activity (p < 0.01). PMID- 4290838 TI - Crystal bodies in the ultrastructure of multiform glioblastoma. PMID- 4290839 TI - [Sequelae of salivary gland injuries]. PMID- 4290840 TI - Semi-automated assays for urinary 17-ketogenic steroids. A comparison of bismuthate and periodate oxidation methods. PMID- 4290841 TI - Influences of Po2 and pH on resting and active tensions of pulmonary arterial strips. PMID- 4290842 TI - Correlation of B virus and herpes simplex virus antibodies in human sera. PMID- 4290843 TI - [The pressor response to angiotensin and to noradrenaline in subjects with hepatic diseases]. PMID- 4290844 TI - Buckthorn polyneuropathy. PMID- 4290846 TI - Effect of thirst and water load on the hypothalamic regulation of the adrenal in the pigeon (Columba livia domestica L.). PMID- 4290845 TI - [Punch biopsies of the liver. Phase-contrast microscopic examination]. PMID- 4290847 TI - Phosphatase activity in the initial phase of healing of skin wounds. Histochemical comparison between the metal-salt and azo-dye methods. PMID- 4290848 TI - Some metabolic changes during the chick's ontogenesis. A preliminary report. PMID- 4290849 TI - Pseudohypoparathyroidism 1942-1966. A negative progress report. PMID- 4290850 TI - The detection of hyaluronic acid in the serum and urine of a patient with nephroblastoma. PMID- 4290851 TI - [Effects of purified collagenases from C1. perfringens and C1. histolyticum culture filtrates on the collagen of human auricular appendage slices]. PMID- 4290852 TI - Puromycin: a potent metabolic effect independent of protein synthesis. PMID- 4290853 TI - Inhibition of DNA synthesis in ascites hepatoma cells by normal liver extract. PMID- 4290854 TI - The isolation of aribonucleic acid fraction from rabbit reticulocytes which enhances amino acid incorporation into protein. PMID- 4290855 TI - Virus content of Shope papillomas of cottontail rabbits. PMID- 4290856 TI - Utilization of oxygen by transplanted tumors in vivo. PMID- 4290857 TI - Glucose consumption by transplanted tumors in vivo. PMID- 4290858 TI - Relationship between oxygen and glucose consumption by transplanted tumors in vivo. PMID- 4290859 TI - Common features of the base composition of rapidly labeled RNA of nucleoli in a number of experimental tumors. PMID- 4290860 TI - Ribonucleic acid components of BAI strain A (myeloblastosis) avian tumor virus. PMID- 4290861 TI - Muscular subaortic stenosis. The direct relation between the intraventricular pressure difference and the left ventricular ejection time. PMID- 4290862 TI - Electron microscopy of some human hepatomas. PMID- 4290864 TI - The dissociation of D-fructose 1,6-diphosphatase by adenosine 5'-phosphate. PMID- 4290863 TI - Succinic thiokinase. IV. Improved method of purification, arsenolysis of guanosine triphosphate, succinate-dependent guanosine triphos- phatase activity, and some other properties of the enzyme. PMID- 4290865 TI - Quantitative determination of the ribosomal ribonucleic acid content of liver and Novikoff hepatoma from fed and from fasted rats. PMID- 4290866 TI - Kinetic studies of dogfish liver glutamate dehydrogenase with diphosphopyridine nucleotide and the effect of added salts. PMID- 4290868 TI - Effect of sodium chloride on the activity of a soluble malate dehydrogenase from pea seeds. PMID- 4290867 TI - Structural properties of stellacyanin, a copper mucoprotein from Rhus vernicifera, the Japanese lac tree. PMID- 4290869 TI - Biosynthesis of cardiolipin in Escherichia coli. PMID- 4290871 TI - Glomus jugulare tumour with changing drum membrane picture. PMID- 4290870 TI - The role of hypothesis testing in clinical trials. Biometrics seminar. PMID- 4290872 TI - Species specificity of tyrosine transfer RNA's from Escherichia coli and yeast. PMID- 4290873 TI - Histochemistry of the chick esophagus and trachea. II. Enzymes, nucleic acids, proteins, carbohydrates, and fats. PMID- 4290874 TI - The inhibitory effect of chloroquine on rat adipose tissue metabolism in vitro. PMID- 4290875 TI - Case records of the Massachusetts General Hospital. Case 28-1967. PMID- 4290876 TI - Intraperitoneal lipid granuloma. PMID- 4290877 TI - [Apropos of virilizing tumors of the ovaries]. PMID- 4290878 TI - Overproduction of deoxyribonucleic acid as a cause of cell death in cultures infected with canine hepatitis virus. PMID- 4290879 TI - Placental pathology. V. Placental lesions of cattle experimentally infected with infectious bovine rhinotracheitis virus. PMID- 4290880 TI - Reactivation of antibody-neutralized foot-and-mouth disease virus by organic chemicals and inhibition by 1-butanol. PMID- 4290881 TI - Complement-fixing antibodies as a measure of immunity of cattle to the virus of vesicular Stomatitis New Jersey. PMID- 4290882 TI - Association of myxovirus parainfluenza-3 with pneumoenteritis of calves: virus isolation. PMID- 4290883 TI - [Polyneuritic paramyloidosis of the Portuguese type (familial amyloid polyneuropathy). A differential diagnosis from ulcero-mutilating acropathy]. PMID- 4290884 TI - Characteristics of isolated and purified preparations of the outer and inner membranes of mitochondria. PMID- 4290885 TI - The pathogenesis of encephalitis caused by the infectious bovine rhinotracheitis virus. PMID- 4290886 TI - [Relations between structure and capacity of various amino acids to antagonize the antipoliomyelitic action of guanidine]. PMID- 4290887 TI - [Selectivity of the antagonism of some methylated substances on the antipoliomyelitic effect in vitro of guanidine]. PMID- 4290888 TI - [Lack of antiguanidine action by monomethy- and monoethyl-guanidine]. PMID- 4290889 TI - [Antagonism, by homocysteine and alpha-amino-butyrric acid, of the antipolio activity in vitro of guanidine]. PMID- 4290890 TI - [Viral ribonucleic acids infecting cells not receptive to the complete virus]. PMID- 4290891 TI - Physical and topological properties of circular DNA. AB - Several types of circular DNA molecules are now known. These are classified as single-stranded rings, covalently closed duplex rings, and weakly bonded duplex rings containing an interruption in one or both strands. Single rings are exemplified by the viral DNA from phiX174 bacteriophage. Duplex rings appear to exist in a twisted configuration in neutral salt solutions at room temperature. Examples of such molecules are the DNA's from the papova group of tumor viruses and certain intracellular forms of phiX and lambda-DNA. These DNA's have several common properties which derive from the topological requirement that the winding number in such molecules is invariant. They sediment abnormally rapidly in alkaline (denaturing) solvents because of the topological barrier to unwinding. For the same basic reason these DNA's are thermodynamically more stable than the strand separable DNA's in thermal and alkaline melting experiments. The introduction of one single strand scission has a profound effect on the properties of closed circular duplex DNA's. In neutral solutions a scission appears to generate a swivel in the complementary strand at a site in the helix opposite to the scission. The twists are then released and a slower sedimenting, weakly closed circular duplex is formed. Such circular duplexes exhibit normal melting behavior, and in alkali dissociate to form circular and linear single strands which sediment at different velocities. Weakly closed circular duplexes containing an interruption in each strand are formed by intramolecular cyclization of viral lambda-DNA. A third kind of weakly closed circular duplex is formed by reannealing single strands derived from circularly permuted T2 DNA. These reconstituted duplexes again contain an interruption in each strand though not necessarily regularly spaced with respect to each other. PMID- 4290892 TI - Viral respiratory diseases in Nigeria: a serological survey, II. complement fixing antobody levels of adenoviruses, respiratory syncytial virus, psittacosis virus. PMID- 4290893 TI - [Virus diseases in children (II): Cytomegalic disease]. PMID- 4290894 TI - [Virus diseases in children (IV): Adenovirus]. PMID- 4290895 TI - Oncogenicity of bovine adenovirus type 3 in hamsters. PMID- 4290897 TI - Multiplication of an attenuated RV11 strain (type SAT12) of foot-and-mouth disease virus in sheep. PMID- 4290896 TI - Increased angiotensin formation in response to carotid occlusion in the dog. PMID- 4290898 TI - Electron microscopic studies on lumpy skin disease virus type "Neethling". PMID- 4290900 TI - Soluble collagen proline hydroxylase and its substrates in several animal tissues. PMID- 4290899 TI - The susceptibility of differentiating muscle clones to Rous sarcoma virus. PMID- 4290902 TI - Spin-labeled hemoglobin. PMID- 4290901 TI - Requirement for the integrity of the viral genome for the induction of host DNA synthesis by polyoma virus. PMID- 4290903 TI - Nucleic acid homology studies of SV 40 virus-transformed and normal hamster cells. PMID- 4290904 TI - ESR study of nucleosides and nucleotides bombarded with hydrogen atoms. PMID- 4290905 TI - [Epidemics caused by adenovirus in Norwegian military recruits]. PMID- 4290906 TI - Biological half-life of a synthetic corticotrophin in men. PMID- 4290907 TI - The polycystic ovary. VI. A hilus cell tumour of the ovary associated with polycystic ovarian disease: in vivo and in vitro studies. PMID- 4290908 TI - Oestrogens in virilizing adrenal carcinoma. PMID- 4290909 TI - Effect of cervical sympathetic stimulation on accommodation in monkeys. An example of a beta-adrenergic, inhibitory effect. PMID- 4290910 TI - Air sampling and analysis with microcolumns of silica gel. PMID- 4290911 TI - Application of x-ray diffraction to the determination of chrysotile in bulk or settled dust samples. PMID- 4290912 TI - The relationship of parathyroid activity to pyrophosphate excretion. PMID- 4290913 TI - ACTH induced changes in tryptophan turnover along induceable pathways in man. PMID- 4290914 TI - Response of pineal sympathetic nerve processes and endings to angiotensin. PMID- 4290915 TI - Use of neutron activation in the characterization of small quantities of nucleic acids. PMID- 4290916 TI - Nucleic acid of influenza virus. PMID- 4290917 TI - Stretchings and yawnings induced by adrenocorticotrophic hormone. PMID- 4290918 TI - Effect of prolonged ACTH administration on the gonads of sexually mature chickens. PMID- 4290919 TI - Metabolic activities of the endolymphatic sac. An enzyme histochemical and autoradiographic study. PMID- 4290920 TI - [On the influence of hydrocortisone on the elimination rate of ethanols]. PMID- 4290921 TI - Effects of 4-hydroxypyrazolo(3,4-d)pyrimidine upon the catabolism of purines by various tissues of the rat and upon the rate of growth of Morris 5123-C hepatoma. PMID- 4290922 TI - [Preliminary observations on the ultrastructure of a transplantable "granulosa cell myoblastoma" in C3H/f mice]. PMID- 4290923 TI - [Phosphofructokinase of rabbit muscle as a function of the oxido-reduction capacity]. PMID- 4290924 TI - A case report of two primary tumours: bronchial carcinoid and adenocarcinoma in the same lung. PMID- 4290925 TI - Experimental infection of calves with hemadsorbing enteric (HADEN) virus. PMID- 4290926 TI - Infection of germfree pigs with a porcine enterovirus. PMID- 4290927 TI - Morphological changes in cells transformed in vitro by bovine papilloma virus. PMID- 4290928 TI - In vitro activity of some 2-N3-guanidinobenzimidazole derivatives against poliovirus. PMID- 4290929 TI - Rhinoviruses isolated from Japanese children with common cold. PMID- 4290930 TI - Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism. PMID- 4290931 TI - [Considerations with reference to 20 cases of subglottic edematous laryngitis admitted to the Section of Pediatrics, Suceava, 1963-1964]. PMID- 4290932 TI - A study on the sensitivity test of cancer cells to anticancer drugs. PMID- 4290933 TI - Effect of angiotensin on renal transport of sodium in renovascular hypertension. PMID- 4290934 TI - Estrogen influence on pituitary and adrenal function in the rat. PMID- 4290935 TI - Response of rat ovarian cholesterol to gonadotropins and anterior pituitary hormones. PMID- 4290936 TI - Antilipolytic effects of sulfonylurea drugs on induced lipolysis in isolated fat cells of the rat. PMID- 4290937 TI - The osmiophilic particles of astrocytes. Viruses, lipid droplets or products of secretion? PMID- 4290938 TI - Microchemical and histochemical observations in a case of Krabbe's leukodystrophy. PMID- 4290939 TI - Cadmium-induced selective lesions of sensory ganglia. PMID- 4290940 TI - Sudden deafness associated with adenovirus infection. PMID- 4290941 TI - Delayed diagnosis of pregnancy-associated trophoblastic disease. PMID- 4290942 TI - Renin in experimental "toxemia of pregnancy". PMID- 4290943 TI - Plasma and adrenal corticosterone levels following exposure of the two-day-old rat to various stressors. PMID- 4290945 TI - Aerosol stability of three acute respiratory disease viruses. PMID- 4290944 TI - Immunologic restoration of neonatally thymectomized rats with thoracic duct lymphocytes. PMID- 4290946 TI - Incompetent relationship between coxsackievirus A6 ribonucleic acid and mouse cells. PMID- 4290947 TI - Effect of heat and nucleotides on human erythrocyte inorganic pyrophosphatase. PMID- 4290948 TI - Comparative viral sensitivity of bovine and avian cells before and after storage in liquid nitrogen. PMID- 4290949 TI - Relation of renal arterial pressure to activity of renin-angiotensin system in renal hypertension. PMID- 4290950 TI - Changes in the adrenal glands and other organs of intact and hypophysectomized rats following ACTH and adrenal steroids. PMID- 4290952 TI - [On the neurovirulence test of poliomyelitis-live vaccine. IV. Pathomorphology of monkey poliomyelitis through neuropathogenic poliovirus type 3 (Saukett strain) after intralumbar injection in comparison to the attenuated poliovirus strains]. PMID- 4290951 TI - The skin of primates. XXXII. The Philippine tarsier (Tarsius syrichta). PMID- 4290953 TI - [On the neurovirulence test of poliomyelitis-live vaccine. 3. Pathomorphology of monkey poliomyelitis through attenuated polioviruses after intrathalamic infection under particular consideration of differences between virus types]. PMID- 4290954 TI - The formation of unpaired electrons on sulphur atoms in irradiated dry proteins as studied by electron spin resonance. PMID- 4290955 TI - [Statistical study of unilateral exophthalmos of an orbital cause with histological verification]. PMID- 4290956 TI - [Myoblastoma myoblasticum (Abrikosov's tumor)]. PMID- 4290957 TI - The role of virus in radiation leukemogenesis. PMID- 4290958 TI - Histochemical study on alkaline phosphatase activity in human neoplasms. PMID- 4290959 TI - Adhesiveness of cancer cells as revealed by microincineration technique. PMID- 4290960 TI - Separation and quantitative determination of 32P-labelled lipids from brain particulates by thin-layer chromatography. PMID- 4290962 TI - Improvement of the plaque assay of herpes simplex virus in HeLa cells. PMID- 4290961 TI - Viral oncolysis: increased immunogenicity of host cell antigen associated with influenza virus. AB - A2G mice could be solidly immunized against the Ehrlich ascites tumor by single intraperitoneal injections of homogenized and lyophilized tumor cells which had been infected with oncolytic strains of influenza A virus. Similar homogenates from noninfected tumor cells were not immunogenic, even when mixed with egg-grown virus. The immunizing principle in viral oncolysates could not be separated from the oncolytic virus by differential centrifugation or adsorption to and elution from red cells. It could be inhibited by antibody raised in rabbits against the egg-grown oncolytic virus. This reaction showed serologic specificity. Thus, the immunogenicity of an oncolysate produced with the WSA strain of neurotropic influenza virus could be inhibited by rabbit anti-WSA, but not by rabbit antibody to the TUR strain of fowl plague virus. Conversely, the immunogenicity of an oncolysate prepared with the TUR strain could be inhibited by rabbit anti-TUR, but not by anti-WSA. When mice were preimmunized (primed) with egg-grown WSA virus, their antitumor response to a later injection of WSA oncolysate was of the anamnestic type. Priming with egg-grown influenza B virus had no such effect. It was concluded that the immunogenicity of certain host cell components was greatly increased by incorporation into the makeup of the oncolytic virus. PMID- 4290963 TI - An outbreak of pharyngoconjunctival fever due to adenovirus type 3. PMID- 4290964 TI - Infection of cattle with parainfluenza 3 virus with special reference to udder infection. I. Virus isolation from milk. PMID- 4290965 TI - Infection of cattle with parainfluenza 3 virus with special reference to udder infection. II. Pathogenicity of the virus for cattle, with particular reference to the mammary gland. PMID- 4290966 TI - Immunofluorescence of Japanese encephalitis virus infection in vitro: localization of viral antigen in canine cerebellar tissue cultures. PMID- 4290967 TI - Changes in the EEG of the hypothalamus and limbic system after administration of ACTH, SU-4885 and ACH in rabbits with special reference to neurohumoral feedback regulation of pituitary-adrenal system. PMID- 4290968 TI - Effect of thymectomy on transplantation resistance induced by polyoma tumour homografts. PMID- 4290969 TI - Comparison of the effect of alpha- and gamma-radiation on an enzyme. PMID- 4290970 TI - A culture method of growing Entamoeba histolytica and other anaerobic amoebae for the study of their nuclear division. PMID- 4290972 TI - The central nervous system pathology in multiple neurofibromatosis. PMID- 4290971 TI - [Carcinomatous neuromyopathy]. PMID- 4290973 TI - The use of combined hyperbaric oxygen and Polymyxin B in the treatment of Pseudomonas infections of mice. PMID- 4290974 TI - The degradation of mature collagen: a laboratory study. PMID- 4290976 TI - A generalized herpes virus infection in owl monkeys. REP NO 670. PMID- 4290975 TI - [Actinic treatment of malignant tumors of the maxilla; preoperative irradiation]. PMID- 4290977 TI - [Proteins and enzymes of subcellular structures in alcoholic and alimentary lesions of the liver in experiments]. PMID- 4290978 TI - [Antigenic and immunological relationships between the A sub-types of the foot and-mouth disease virus. 1. After inoculation of guinea-pigs with active virus]. PMID- 4290979 TI - [Gastric ultrastructures in cortisone-treated rats]. PMID- 4290980 TI - [Germinal carcinoma and immature trophoblastomas]. PMID- 4290981 TI - [Testicular metastasis of a muciparous gastric epithelioma]. PMID- 4290982 TI - Selected hematological and biochemical tests performed with blood and serum of adult rainbow trout (Salmo gairdneri) with a high incidence of hepatoma. PMID- 4290983 TI - The inhibition of streptococci by lactoperoxidase, thiocyanate and hydrogen peroxide. The effect of the inhibitory system on susceptible and resistant strains of group N streptococci. AB - 1. The growth of the lactoperoxidase-sensitive Streptococcus cremoris 972 in a synthetic medium was inhibited by lactoperoxidase and thiocyanate. The glycolysis and oxygen uptake of suspensions of Strep. cremoris 972 in glucose or lactose were also inhibited. The lactoperoxidase-resistant Strep. cremoris 803 was not inhibited under these conditions but was inhibited in the absence of a source of energy. 2. Lactoperoxidase (EC 1.11.1.7), thiocyanate and hydrogen peroxide completely inhibited the hexokinases of non-metabolizing suspensions of both strains. The inhibition was reversible, hexokinase and glycolytic activities of Strep. cremoris 972 being restored by washing the cells free from inhibitor. The aldolase and 6-phosphogluconate-dehydrogenase activities of Strep. cremoris 972 were partially inhibited but several other enzymes were unaffected. 3. The resistance of Strep. cremoris 803 to inhibition was not due to the lack of hydrogen peroxide formation, to the destruction of peroxide, to the inactivation of lactoperoxidase or to the operation of alternative pathways of carbohydrate metabolism. 4. A ;reversal factor', which was partially purified from extracts of Strep. cremoris 803, reversed the inhibition of glycolysis of Strep. cremoris 972. The ;reversal factor' also catalysed the oxidation of NADH(2) in the presence of an intermediate oxidation product of thiocyanate and was therefore termed the NADH(2)-oxidizing enzyme. 5. The NADH(2)-oxidizing enzyme was present in lactoperoxidase-resistant streptococci but was absent from lactoperoxidase sensitive streptococci. PMID- 4290985 TI - Substrate activation and inhibition in coenzyme-substrate reactions cyclohexanol oxidation catalysed by liver alcohol dehydrogenase. AB - 1. The activity of liver alcohol dehydrogenase with cyclohexanol and cyclohexanone as substrates was studied, and the initial-rate parameters were determined from measurements at low substrate concentrations. In contrast with aliphatic ketones, cyclohexanone is a fairly good substrate, although less active than aliphatic aldehydes. The Michaelis constant for cyclohexanol is of the same order as that for ethanol, and the maximum rate and Michaelis constant for NAD(+) obtained with cyclohexanol are very similar to those obtained with primary aliphatic alcohols. The data for this substrate at low concentrations are therefore consistent with a compulsory-order mechanism in which ternary complexes are not rate-limiting. 2. With large concentrations of NAD(+), substrate activation is observed with increasing concentrations of cyclohexanol, whereas with small NAD(+) concentrations substrate inhibition is observed. This complex behaviour is explained by a mechanism previously proposed for this enzyme, which also satisfactorily described the kinetics of oxidation of primary and secondary aliphatic alcohols and aldehydes, including the substrate inhibition exhibited by primary alcohols, and the reduction of aldehydes. The activation with large concentrations of both NAD(+) and cyclohexanol is attributed to the formation of an abortive complex, E.NADH.ROH, from which NADH dissociates more rapidly than from the normal product complex E.NADH. Substrate inhibition in the presence of small NAD(+) concentrations is attributed to the formation of an active complex E.ROH, with which NAD(+) reacts more slowly than with the free enzyme. 3. Some support for these mechanisms of substrate activation and inhibition is obtained by approximate theoretical calculations, and their applicability to other two substrate reactions that exhibit complex initial-rate behaviour, as a more likely alternative to the postulate of a second binding site for the substrate, is suggested. PMID- 4290984 TI - Glucose metabolism in the mucosa of the small intestine. Glycolysis in subcellular preparations from the cat and rat. AB - 1. Lactic acid formation in supernatant fractions of homogenates of cat or rat small-intestinal mucosa was measured under optimum conditions with glucose, fructose, glucose 6-phosphate, fructose 1,6-diphosphate or 3-phosphoglycerate as substrate. 2. Between 80 and 107% of the glycolytic activity of the homogenate was recovered in these particle-free preparations when glucose, fructose, glucose 6-phosphate or fructose 1,6-diphosphate was used as substrate. 3. Evidence was obtained that hexokinase and phosphofructokinase were the rate-limiting enzymes in the initial sequence of glycolytic reactions. The limitation of rate by hexokinase was much more pronounced in preparations from the cat than in those from the rat. 4. With subcellular preparations from cat or rat small intestine lactic acid was also formed from ribose 5-phosphate and at rates similar to those observed with glucose. 5. A higher rate of glycolysis was observed with glucose 6 phosphate as substrate with preparations from the proximal half of the small intestine of the rat as compared with the distal half. 6. Mucosal preparations from rats starved for 24-48hr. exhibited only about one-quarter of the glycolytic activity of those of fed control groups. The decreased rate of formation of lactic acid from either glucose or fructose was mainly due to a decrease in the activity of hexokinase(s). The activities of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase and a number of other enzymes were not significantly decreased by starvation. 7. The results are discussed in relation to metabolic control of glycolysis in other mammalian tissues. PMID- 4290986 TI - Interactions of protein-denaturing salts with model amides. PMID- 4290987 TI - Studies of nucleotide sequences in tobacco mosaic virus ribonucleic acid. 3. Periodate oxidation and semicarbazone formation. PMID- 4290988 TI - Studies of nucleotide sequences in tobacco mosaic virus ribonucleic acid. IV. Use of aniline in stepwise degradation. PMID- 4290989 TI - Sphingosine and its lower homologues from bovine heart sphingomyelin fraction. PMID- 4290990 TI - Biological characterization of a new and highly potent synthetic analogue of corticotrophin. PMID- 4290991 TI - The adrenocorticotropic action of a new synthetic pentacosapeptide. PMID- 4290992 TI - Course of hypertension during prolonged treatment with heterologous renin. PMID- 4290993 TI - The effect of perchlorate ion and some pharmacological agents on the sensitivity of the frog (Rana pipiens) rectus abdominis to acetylcholine. PMID- 4290994 TI - On the mechanism of potentiation of kinins by inhibitors of the fibrinolytic system. PMID- 4290995 TI - Effects of angiotensin II and epinephrine infusion on juxtaglomerular cell granularity and arterioles of the rat kidney. PMID- 4290996 TI - Effect of age, sex, hypophysectomy and gonadectomy on plasma corticosterone levels and adrenal weights following the administration of ACTH and stress. PMID- 4290997 TI - [Radioimmunoassay of insulin]. PMID- 4290998 TI - [Immunoassay of ACTH]. PMID- 4290999 TI - [Study on the effect of plasmin in the blood on ACTH inactivation]. PMID- 4291000 TI - Antibodies to synthetic corticotrophin. PMID- 4291001 TI - Oncogenicity of Bryan strain rous sarcoma virus for rodents. PMID- 4291002 TI - Transfer of metabolic energy to sodium. PMID- 4291003 TI - L-Lysine dehydrogenase deficiency in a patient with congenital lysine intolerance. PMID- 4291004 TI - Alpha-Glycerophosphate dehydrogenase in mouse adrenal cortex. PMID- 4291005 TI - Susceptibility of Old World monkeys to Yaba virus. PMID- 4291006 TI - Interaction of poly-2-vinylpyridine-1-oxide with silicic acid. PMID- 4291007 TI - The structure and function of the adhesive organ in strigeid trematodes. PMID- 4291008 TI - Stimulation of DNA synthesis and complement-fixing antigen production by SV40 in human diploid cell cultures: evidence for "abortive" infection. PMID- 4291009 TI - Acquisition of enzyme function by mouse kidney cells abortively infected with papovavirus SV40. PMID- 4291010 TI - Viral antigens in differentiating muscle colonies after infection with Rous sarcoma virus in vitro. PMID- 4291011 TI - Protein synthesis related to epidermal differentiation. PMID- 4291012 TI - Malignant conversion of cells in vitro by carcinogens and viruses. PMID- 4291013 TI - Induction of DNA synthesis by SV40. PMID- 4291014 TI - An intermediate in the synthesis of poliovirus RNA. PMID- 4291015 TI - Laboratory values in severely stunted mental defectives. PMID- 4291016 TI - Changes in nicotinamide adenine dinucleotide concentration of Bacillus cereus during growth. PMID- 4291017 TI - Intracellular distribution of vitamin D in rat liver. PMID- 4291018 TI - [Homology between the genome of avian myeloblastosis virus (AMV) and the cellular genome]. PMID- 4291020 TI - Studies on lipoamide dehydrogenase of Bakers' yeast. VI. Molecular weight and some properties. PMID- 4291019 TI - Calfhood immunization against an experimental Parainfluenza and Pasteurella challenge. AB - An inactivated vaccine including Parainfluenza-3, PASTEURELLA MULTOCIDA and PASTEURELLA HEMOLYTICA stimulated good immunity in calves against an experimental shipping fever challenge. Calves were first vaccinated when 4 to 10 weeks old and revaccinated at weaning age. There were higher HI titers, lower temperatures, and less lung lesions recorded in the vaccinated group when compared to the control animals. PMID- 4291021 TI - Possible occurrence of cytochromes in isolated thymus nuclei. PMID- 4291022 TI - Growth inhibition of polyoma-transformed cells by contact with static normal fibroblasts. PMID- 4291023 TI - Hormonal regulation of plasma free fatty acid concentration in ruminants. PMID- 4291024 TI - Some nuclear-substituted derivatives of alpha-methyldopa. PMID- 4291025 TI - 1,3,2-diazaphosphorine 2-oxides. 3. Preparation and biological evaluation of some 1,3-bis(aralkyl)-2-halo-1,3,2-diazaphosphorine 2-oxides and related compounds. PMID- 4291026 TI - Some hydrazine derivatives of (4-biphenyl)glyoxal. PMID- 4291027 TI - Excision of dimers and hydrates from ultraviolet-irradiated poly U by pancreatic ribonuclease. PMID- 4291028 TI - Abnormal metabolic response to ultraviolet light of a recombination deficient mutant of Escherichia coli K12. PMID- 4291029 TI - The removal of the bound ADP of F-actin. PMID- 4291030 TI - Renin activity of the kidney in the spontaneously hypertensive rat. PMID- 4291031 TI - Transient pulmonary densities around retained lipiodol. PMID- 4291032 TI - The influence of the environment on avian leucosis. PMID- 4291033 TI - [Characterization of types of enzymatic activities in antigenic extracts of Aspergillus fumigatus after electrophoresis and immunoelectrophoresis in agarose]. PMID- 4291034 TI - Studies on oxidative phosphorylation. XI. Energy-dependent reduction of diphosphophyridine nucleotide by ene-diol compounds in the presence of dyes. PMID- 4291035 TI - Peptide-associated and antigenic changes accompanying periodic acid oxidation of human plasma orosomucoid. PMID- 4291036 TI - An intermediate of oxidative phosphorylation from Alcaligenes faecalis. PMID- 4291037 TI - Bile salts and calcium absorption. AB - 1. The study of the effect of bile salts on enhancing calcium absorption in the rachitic chick has been extended to bile salts not present in chick bile, e.g. glycine conjugates and bile alcohol sulphates. 2. Bile and bile salts cause an increase in calcium absorption from sparingly soluble calcium hydrogen phosphate when compared with a suspension of calcium hydrogen phosphate in saline. 3. If the bile ducts of normal rats are tied the absorption of calcium from calcium hydrogen phosphate decreases but can be restored by giving bile salts with the calcium salt. 4. Bile salts increase solubility in water of the sparingly soluble calcium salts, phytate and phosphate at pH values between 6 and 8. 5. Bile salts increase the solubility in lipid solvents of calcium in approximately the same proportion as they increase the absorption of calcium from the gut. 6. The physiological role of bile in calcium absorption and its mode of action are discussed. PMID- 4291038 TI - Bile and the absorption of strontium and iron. AB - 1. Strontium absorption was studied in vivo with loops of ileum in rachitic chicks and found to be increased by vitamin D(3), bile salts and sodium lauryl sulphate. 2. Bile salts and sodium lauryl sulphate rendered strontium soluble in butanol-benzene (1:1, v/v). 3. Bile was not concerned in the absorption of iron in rats from its water-soluble form, ferrous sulphate. 4. Ligation of the bile ducts in rats caused a decrease in the absorption of iron presented as its sparingly soluble phosphate. 5. The effect of bile on cation absorption is discussed. PMID- 4291039 TI - The control of rat-heart phosphofructokinase by citrate and other regulators. AB - 1. The effects of ATP, inorganic phosphate and citrate on the relationship between fructose 6-phosphate concentration and initial velocity of reaction has been investigated with a partially purified preparation of rat-heart phosphofructokinase. 2. At low concentrations of ATP (<80mum) rate curves for fructose 6-phosphate approximated to Michaelis-Menten kinetics. At higher ATP concentrations rate curves were sigmoid, the K(m) for fructose 6-phosphate increased and the reaction appeared to be first-order with respect to fructose 6 phosphate at concentrations above its K(m) and of a higher order at concentrations below its K(m). Inorganic phosphate lowered the K(m) for fructose 6-phosphate and the concentration at which the apparent kinetic order decreased. 3. At 40mum-ATP, citrate was an activator at low concentration (<100mum) and an inhibitor at higher concentrations. At 0.5mm-ATP, citrate was inhibitory at all concentrations tested. 4. A new method for phosphofructokinase assay using [U (14)C]fructose 6-phosphate is described which allows measurements to be made of the velocity of the forward reaction at known concentrations of the products of the reaction. With this method confirmatory evidence has been obtained that concentrations of ATP, AMP, phosphate and citrate may regulate phosphofructokinase in the perfused rat heart. PMID- 4291040 TI - The inhibition of cationic myotropic drugs by compounds 48/80 and 46/108. PMID- 4291041 TI - Antimycin-insensitive oxidation of succinate and reduced nicotinamide-adenine dinucleotide in electron-transport particles. I. pH dependency and hydrogen peroxide formation. PMID- 4291042 TI - Antimycin-insensitive oxidation of succinate and reduced nicotinamide-adenine dinucleotide in electron-transport particles. II. Steroid effects. PMID- 4291043 TI - Purification of human renin. PMID- 4291044 TI - Simultaneous measurements of 24na+-efflux and pyridine nucleotides in slices of rat liver. PMID- 4291045 TI - Regulation of pyruvate dehydrogenase activity in Escherichia coli K12. PMID- 4291046 TI - Mannitol kinase in cell-free extracts of Escherichia coli. PMID- 4291047 TI - The presence of D-malate dehydrogenase (D-malate:NAD oxidoreductase) in Serratia marcescens. PMID- 4291048 TI - Localization of glucosamine-incorporating materials at epithelial surfaces during salivary epithelio-mesenchymal interaction in vitro. PMID- 4291049 TI - Blood corticosterone level of tumor-bearing rats. PMID- 4291050 TI - Electron spin resonance study on the free radicals produced from 4 hydroxyaminoquinoline 1-oxide and its significance in carcinogenesis. PMID- 4291051 TI - Possible transmission of leukemia virus in AKR mice through milk. PMID- 4291052 TI - Free radical produced by interaction of aromatic hydrocarbons with tissue components. PMID- 4291053 TI - [The effect of the virus inhibiting factor on oxidative phosphorylation]. PMID- 4291054 TI - Survival of host mice and induced resistance to transplantable ascites tumors. PMID- 4291055 TI - [The diagnosis of slowness of afferent conduction in peripheral nerve diseases: importance of the extraction of the cerebral evoked potential]. PMID- 4291056 TI - Cellular and humoral aspects of heterotransplantation immunity. PMID- 4291057 TI - [Contribution to the pathology of glioma recurrence]. PMID- 4291058 TI - Neoplasms and the vagus. PMID- 4291059 TI - Mechanisms of intrarenal hemodynamic changes following acute arterial occlusion. PMID- 4291060 TI - Sex difference in resting pituitary-adrenal function in the rat. PMID- 4291061 TI - Relation of fatty acid structure to release and esterification of free fatty acids. PMID- 4291062 TI - Parainfluenza virus immunization. 3. Antigenicity of aqueous, egg-adapted, parainfluenza types 1 and 2 virus vaccines. PMID- 4291063 TI - Colorimetric assays for serum alanine transaminase and lactic dehydrogenase using diazonium zinc salt. PMID- 4291064 TI - Experimental silicosis. The "atypical" reaction in the Syrian hamster. PMID- 4291065 TI - [The solitary and multifocal polymorphic granuloma in the nervous system]. PMID- 4291066 TI - [On the neurovirulence test of poliomyelitis-live vaccine. V. A statistical method for the evaluation of the experiment for the comparison of neurovirulence in the monkey]. PMID- 4291067 TI - Massive blood replacement. PMID- 4291068 TI - A rapid assay for urinary porphyrins by thin-layer chromatography. PMID- 4291069 TI - Biosynthesis of mannophosphoinositides by Mycobacterium phlei. The family of dimannophosphoinositides. PMID- 4291070 TI - The binding of nucleotides and calcium to the extracellular nuclease of Staphylococcus aureus. Studies by gel filtration. PMID- 4291071 TI - Base sequence at the 5'-linked terminus of tobacco mosaic virus ribonucleic acid. PMID- 4291072 TI - Studies on the polymer of adenosine diphosphate ribose. I. Enzymic formation from nicotinamide adenine dinuclotide in mammalian nuclei. PMID- 4291073 TI - Studies on the polymer of adenosine diphosphate ribose. II. Characterization of the polymer. PMID- 4291074 TI - Adenosine triphosphate conservation in biosynthetic regulation. Escherichia coli phosphoribosylpyrophosphate synthase. PMID- 4291075 TI - Epiandrosterone excretion in man. PMID- 4291076 TI - Relationship between the concentration of corticosteroids in avian plasma and nasal gland function. PMID- 4291077 TI - Separation of oxytocin from the substances that interfere with its biological assay on the isolated rat mammary gland. PMID- 4291078 TI - Reactivation of ether-inactivated infectious bovine rhinotracheitis virus. PMID- 4291079 TI - Enzymatic activity of primary isolates of staphylococci in relation to antibiotic resistance and phage type. PMID- 4291080 TI - Electronic spectra of P2,As2, and Sb2 molecules. PMID- 4291081 TI - Foot-And-Mouth Disease. PMID- 4291082 TI - [Rheumatic lesions of the peripheral nervous system]. PMID- 4291083 TI - [Thrombocytopoiesis in patients with nonspecific infection polyarthritis and its change under the influence of ACTH and cortisone treatment]. PMID- 4291084 TI - Cardiac effects of angiotensin injections into perfused right coronary artery. PMID- 4291085 TI - Ovariectomy and suckling intensity effects on mammary nucleic acid, prolactin, and ACTH. PMID- 4291086 TI - The clinical significance of cytomegalovirus infection in renal transplant recipients. PMID- 4291087 TI - Wilm's tumour: results of treatment by early post-operative radiotherapy. PMID- 4291089 TI - [Content and distribution of sulfhydryl and alpha-acylamido-carboxyl groups in regenerating structures under the influence of hormones]. PMID- 4291088 TI - Adrenal corticoid levels in human cerebrospinal fluid. PMID- 4291091 TI - Characteristics of bovine mammillitis virus. PMID- 4291090 TI - Aerobic metabolism of Streptococcus agalactiae. AB - Streptococcus agalactiae cultures possess an aerobic pathway for glucose oxidation that is strongly inhibited by cyanide. The products of glucose oxidation by aerobically grown cells of S. agalactiae 50 are lactic and acetic acids, acetylmethylcarbinol, and carbon dioxide. Glucose degradation products by aerobically grown cells, as percentage of glucose carbon, were 52 to 61% lactic acid, 20 to 23% acetic acid, 5.5 to 6.5% acetylmethylcarbinol, and 14 to 16% carbon dioxide. There was no evidence for a pentose cycle or a tricarboxylic acid cycle. Crude cell-free extracts of S. agalactiae 50 possessed a strong reduced nicotinamide adenine dinucleotide (NADH(2)) oxidase that is also cyanide sensitive. Dialysis or ultrafiltration of the crude, cell-free extract resulted in loss of NADH(2) oxidase activity. Oxidase activity was restored to the inactive extract by addition of the ultrafiltrate or by addition of menadione or K(3)Fe(CN)(6). Noncytochrome iron-containing pigments were present in cell-free extracts of S. agalactiae. The possible participation of these pigments in the respiration of S. agalactiae is presently being studied. PMID- 4291092 TI - An electron microscopy study of phosphatase activity in the endothelial cells of rabbit aorta. PMID- 4291093 TI - Ultraviolet sensitivity and functional capacity in bacteriophage T4. PMID- 4291094 TI - Effect of 5-fluorouracil on poliovirus-induced RNA polymerase. PMID- 4291095 TI - Fiber glass. Chemistry and technology. PMID- 4291096 TI - Anti-viral activity of azathymidine and uracil methyl sulphone. PMID- 4291097 TI - Electron spin resonance studies of the reactions of nitric oxide and nitrogen dioxide with polymethyl methacrylate. PMID- 4291098 TI - Complement-fixing antibodies in monkeys bearing tumours induced by Rous sarcoma virus. PMID- 4291099 TI - Adjuvant principle of pertussis vaccine in the mouse. PMID- 4291100 TI - Marker studies of poliovirus. PMID- 4291101 TI - Spectral changes observed in irradiated glycine. PMID- 4291102 TI - Comparative study of fowl plague virus and a virus isolated from man. PMID- 4291103 TI - Primary malignant hepatoma associated with hypoglycaemia. Case report with a review of the literature. PMID- 4291105 TI - Insulin biosynthesis: evidence for a precursor. AB - Human islet cell tumor tissue and isolated islets of Langerhans from rats incorporated radioactive amino acids in vitro into insulin and a larger acid alcohol soluble protein which could be separated from insulin by gel filtration. The amino acids were incorporated into the larger protein earlier than into insulin; only after incubation of islets for approximately 30 minutes did radioactivity begin to appear in insulin. The transfer of about 70 percent of the radioactivity of the larger protein to insulin was demonstrated in the absence of new peptide bond synthesis (cycloheximide), or during incubation with unlabeled amino acid (chase). The results indicate that the larger protein is a precursor in the biosynthesis of insulin. The name "proinsulin" is suggested for this protein. PMID- 4291104 TI - Prostaglandins: members of a new hormonal system. These physiologically very potent compounds of ubiquitous occurrence are formed from essential fatty acids. PMID- 4291106 TI - Oncogenicity by DNA tumor viruses: enhancement after ultraviolet and cobalt-60 radiations. AB - Simian virus-40, polyoma, and LLE46 virus preparations were treated with ultraviolet or gamma radiations (cobalt-60) in a frozen state. Infectivity and induction of complement-fixing antigen and DNA synthesis declined as a logarithmic function of dose, the latter two properties being more resistant than infectivity to radiation by a factor of 2 to 5. Oncogenicity of all three viruses did not decrease with progressive amounts of both types of irradiation, but actually increased in absolute and relative terms (per infectious unit), even at the maximum dose of irradiation used (24,000 ergs per square millimeter per minute and 2.7 x 10(6) rads). PMID- 4291107 TI - Effect of neuraminidase on isozymes of alkaline phosphatase and leucine aminopeptidase. PMID- 4291108 TI - Isolation and culture of chondrocytes from human adult articular cartilage. PMID- 4291109 TI - Preparation, isolation and properties of [35-S] phenylthiocarbamyl angiotensin. PMID- 4291110 TI - The effect of traumatic shock on metabolism of ethyl alcohol in mice. 3. The interaction of treatments by nicotinamide, diphosphopyridinenucleotide and traumatic shock on the rate of whole-body metabolism of ethyl alcohol. PMID- 4291111 TI - Tumour-incidence in progeny of thalidomide-treated mice. PMID- 4291112 TI - Antigenic composition of transplanted rat hepatomas originally induced by 4 dimethylaminoazobenzene. PMID- 4291113 TI - Effect of lysolecithin on the oxygen uptake of tumour cells, polymorphonuclear leucocytes, lymphocytes and macrophages in vitro. PMID- 4291114 TI - Chemical characteristics of microsomal liver specific antigens in the rat. PMID- 4291115 TI - [Cytomegalic viral infection of the salivary glands in kidney transplantations]. PMID- 4291116 TI - [Therapy of neurosyphilis]. PMID- 4291117 TI - [Study on corticosterone secretion rate with reference to normal and hypertensive subjects]. PMID- 4291118 TI - [Effects of various hormones on the serum insulin activity]. PMID- 4291119 TI - Response of blood basophils to Rous sarcoma virus infection in chicks and its significance. PMID- 4291120 TI - Influence of sex hormones on frequency of micturition. PMID- 4291121 TI - Tritiated angiotensin: preparation and purification. PMID- 4291122 TI - Interfering component of vesicular stomatitis virus. PMID- 4291123 TI - Inhibition of neuraminidase by polyanions. PMID- 4291124 TI - Spermagglutination and spermadsorption due to myxoviruses. PMID- 4291125 TI - [Clinical aspects and therapy of the so-called Contergan-polyneuropathy]. PMID- 4291126 TI - Induction of hypertension in rats, with large and small doses of angiotensin. PMID- 4291127 TI - Electron microscopy of human pancreatic tumors of islet cell origin. PMID- 4291128 TI - Psychiatric disorder with intracranial tumors of limbic system. PMID- 4291129 TI - [Adenoviruses isolated in Rumania]. PMID- 4291130 TI - [Research on the urinary excretion of cytomegalic viruses in children living in various collectivities]. PMID- 4291131 TI - [Some observations on the absence of enteroviruses in laboratory samples containing pathogenic bacteria]. PMID- 4291132 TI - The effect of mitomycin C on the nucleotide pool of a growing culture of Escherichia coli. PMID- 4291134 TI - Studies on acid hydrolases. I. A procedure for the preparation of acid deoxyribonuclease and other acid hydrolases. PMID- 4291133 TI - A study of the kinetics of protein and RNA synthesis induced by foot-and-mouth disease virus. PMID- 4291135 TI - Thrombocytopenic purpura in patient with autoimmune haemolytic anaemia, successfully treated with mercaptopurine. PMID- 4291136 TI - Phosphoesterases of Bacillus subtilis. I. Purification and properties of phosphodiesterases. PMID- 4291138 TI - Vasopressin-induced ACTH secretion in man. PMID- 4291137 TI - Evidence for biochemically different types of vesicles in the hepatic microsomal fraction. PMID- 4291139 TI - Adrenal function and serum protein concentrations in a kindred with decreased corticosteroid-binding globulin (CBG) concentration. PMID- 4291140 TI - Tumors and immunological response in rhesus monkeys born after in utero inoculation with Rous sarcoma virus. PMID- 4291142 TI - Epithelial tumors of the rat pancreas. PMID- 4291141 TI - Intracerebral transplantation into rhesus monkeys of cell cultures (NCLP-6) derived from a chemically induced primate hepatocarcinoma. PMID- 4291143 TI - Colonial growth in agar of cells derived from adenovirus-induced hamster tumors. PMID- 4291144 TI - Spectroscopic studies of substantia nigra pigment in human subjects. PMID- 4291145 TI - Renin and acid adenosine triphosphatase as lysosomal enzymes. PMID- 4291147 TI - Purification of 131-I parathyroid hormone with microfine granules of precipitated silica. PMID- 4291146 TI - Separation of antibody-bound and unbound peptide hormones labelled with iodine 131 by talcum powder and precipitated silica. PMID- 4291148 TI - Production of an enzootic-like pneumonia in pigs with "protoplasts" of Haemophilus parainfluenzae. PMID- 4291149 TI - Increased tumour formation by polyoma virus in the presence of non-oncogenic viruses. PMID- 4291150 TI - Molybdenum-thiol complexes as models for molybdenum bound in enzymes. PMID- 4291151 TI - Electron spin resonance of xanthine oxidase substituted with molybdenum-95. PMID- 4291152 TI - Interference not mediated by interferon. PMID- 4291153 TI - 2-dicyanomethylene-1,3-indanedione: a new electron acceptor. AB - The electron affinity of 2-dicyanomethylene-1,3-indanedione (I) (1.33 ev), as computed from charge-transfer spectral analysis and from polarographic measurements of half-wave reduction potential, shows that the incorporation of the 2-dicyanomethylene moiety in 1,2,3-indanetrione (II) enhances its pi-acid character. The electron spin resonance spectrum of the anion radical of I, generated electrolytically in solution, shows hyperfine structure that is due to two nitrogen atoms and four equivalent hydrogen atoms. PMID- 4291154 TI - [Glucide metabolism and synthesis of corticosteroids "in vitro" in the adrenal glands of the rat]. PMID- 4291155 TI - [Critical study of the radioimmunologic methods for the determination of the protein hormones]. PMID- 4291156 TI - On the solution of quartz and precipitation of dolomite in sea water during photosynthesis and respiration. PMID- 4291157 TI - [Respiratory diseases with para-influenzal origin in a children's collectivity]. PMID- 4291158 TI - [Study of the enteric viral flora in children hospitalized in centers for recuperation from poliomyelitis sequels. I]. PMID- 4291159 TI - [Research on the biological properties of some extracts of B. pertussis, B. parapertussis and B. bronchiseptica]. PMID- 4291160 TI - [The significance of microbiological diagnosis in lung diseases]. PMID- 4291161 TI - [Therapy of pulmonary tuberculosis in its current aspects]. PMID- 4291162 TI - Phenindione-induced neuropathy. PMID- 4291163 TI - Experimental herpes simplex infection in the owl monkey. PMID- 4291164 TI - Interference with fibrin stabilization by polymyxin B sulfate. PMID- 4291165 TI - Immunofluorescent studies of virus-induced rabbit papilloma (Shope) in vitro. PMID- 4291166 TI - Complement-fixation reaction of human neoplastic tissue with sera from hamsters bearing virus-induced tumors. PMID- 4291167 TI - Erythropoietin-like effect of a polycythemic virus. PMID- 4291168 TI - Sensitization of the mouse to bradykinin. PMID- 4291169 TI - Rous sarcoma virus infection of chicken buffy coat macrophage. PMID- 4291170 TI - A rapid screening method for detection of T antigens in sera of tumor-bearing hamsters. PMID- 4291171 TI - [Use of actapulgite during different intestinal diseases]. PMID- 4291172 TI - Effects of prednisolone and triamcinolone on corticosteroid levels in parotid fluid, serum, and urine. PMID- 4291173 TI - [On motor end-plate diseases with special reference to myasthenia gravis]. PMID- 4291174 TI - [Correlations between disinhibition of corticotropin secretion by metopirone and fever activation of the corticotropic anterior pituitary lobe function]. PMID- 4291175 TI - [On the control of ACTH secretion]. PMID- 4291177 TI - [Studies on the mechanism of the pressor effect of angiotensin]. PMID- 4291176 TI - [On radio-immunologic determination of growth hormone in blood]. PMID- 4291178 TI - [Experimental calciphylaxis]. PMID- 4291179 TI - [Trophic and vascular influences of the hypothalamus on the adreno-pituitary system]. PMID- 4291180 TI - [Biochemistry and physiology of hypothalamic hormones]. PMID- 4291181 TI - [The effect of an angiotensin infusion on the renal water-electrolyte excretion in liver cirrhosis and hydropic heart insufficiency]. PMID- 4291182 TI - [Ruling principles in adenohypophyseal incretion and its significance]. PMID- 4291183 TI - [Effect of ACTH on the phase of restitution of the adrenal cortex following long term cortisone administration]. PMID- 4291184 TI - [The regulation of the corticotropic function of the hypophysis under pyrogen administration and its pharmacological influence]. PMID- 4291185 TI - Heterogenous bone graft in orbital reconstruction. PMID- 4291186 TI - Generalized eruptive histiocytoma. Enzyme histochemistry and electron microscopy. PMID- 4291187 TI - Clear cell hidradenoma. Histological, histochemical, and electron microscopic studies. PMID- 4291188 TI - Hypophosphatasia in an adult. PMID- 4291189 TI - Bacterial endocarditis due to Actinobacillus actinomycetemcomitans. PMID- 4291190 TI - The isolation of cytomegalovirus from peripheral blood. PMID- 4291191 TI - Milkers' nodules. Some observations on true and false cowpox apropos an outbreak in a closed community. PMID- 4291192 TI - Calcium and magnesium content of rat liver and Morris Hepatoma 5123 tc. PMID- 4291193 TI - Insulin release after ACTH, glucagon and adenosine-3'-5'-phosphate (cyclic AMP) in the perfused isolated rat pancreas. PMID- 4291194 TI - The treatment of infantile spasms and hypsarrhythmia with mogadon. PMID- 4291195 TI - Fine structure of cells infected with respiratory strains of echovirus 11. PMID- 4291196 TI - [On the prevalence of orthodontic anomalies in children with congenital heart defects]. PMID- 4291197 TI - Purification and allosteric properties of a nicotinamide adenine dinucleotide linked D(-)-specific lactate dehydrogenase from Butyribacterium rettgeri. PMID- 4291198 TI - Adrenal insufficiency, diabetes mellitus and amenorrhea: an incomplete form of pluriglandular insufficiency. PMID- 4291199 TI - Discoloration of the teeth in a 24-year-old patient with cystic fibrosis of the pancreas not primarily associated with tetracycline therapy. Report of a case. PMID- 4291200 TI - Effect of periodate oxidation on hemagglutinating and antibody-producing capacities of certain enteroviruses and reoviruses. PMID- 4291201 TI - Stimulation of DNA synthesis in mouse cell line 3T3 by Simian virus 40. PMID- 4291202 TI - New dUTPase and dUDPase activites after infection of Escherichia coli by T2 bacteriophage. PMID- 4291203 TI - Evidence for a dual role for the bacteriophage T4-induced deoxycytidine triphosphate nucleotidohydrolase. PMID- 4291205 TI - The formation of radicals in nucleic acids, nucleoproteins, and their constituents by ionizing radiations. PMID- 4291204 TI - Effects of pH, ionic strength, and metabolic intermediates on the rates of heat inactivation of lactate dehydrogenase isozymes. PMID- 4291206 TI - Spasmolysis and vasodilation. Experience with nylidrin HCl. PMID- 4291207 TI - Common cytochemical properties of cells producing polypeptide hormones, with particular reference to calcitonin and the thyroid C cells. PMID- 4291208 TI - Isolation of a canine herpes virus. PMID- 4291209 TI - Neonatal disease in the dog associated with a herpes-like virus. PMID- 4291210 TI - Studies on guinea pig oocytes. II. Histochemical observations on some phosphatases and lipid in developing and in atretic oocytes and follicles. PMID- 4291212 TI - Specificity of trypsin adsorption onto cellulose, glass, and quartz. PMID- 4291211 TI - In vitro incorporation of palmitate-1-14C into several glycerolipids by normal and regenerating rat liver fractions. PMID- 4291213 TI - Effect of metal ions and EDTA on the activity of rabbit liver fructose 1,6 diphosphatase. PMID- 4291214 TI - The submitochondrial distribution of acid:CoA ligase (AMP) and palmityl CoA:carnitine palmityltransferase in rat liver mitochondria. PMID- 4291215 TI - Evidence for the stimulation by adenocorticotropic hormone of the conversion of cholesterol esters to cholesterol in the adrenal, in vivo. PMID- 4291216 TI - FDP-activation of yeast pyruvate kinase. PMID- 4291218 TI - Fluorine superhyperfine structure in EPR spectra of the single crystal of the myoglobin fluoride. PMID- 4291217 TI - Irreversible inhibition of adenosine triphosphatases, diglyceride kinase and phosvitin kinase of brain by diisopropylphosphorofluoridate. PMID- 4291219 TI - The site of action of cysteamine in irradiated bacteria: an electron spin resonance study. PMID- 4291220 TI - Combined viral and bacterial antigens for canine vaccines. PMID- 4291221 TI - Patterns of interaction between polyribonucleotides and individual DNA strands derived from several vertebrates, bacteria and bacteriophages. PMID- 4291222 TI - TRNA methylases in tumors of animal and human origin. PMID- 4291223 TI - A theory of respiratory chain oxidative phosphorylation. PMID- 4291224 TI - Spin-labeled hemoglobin crystals. PMID- 4291225 TI - Energy transfer in dinucleotides. PMID- 4291226 TI - Characteristics of the renal nuclear receptors for aldosterone. PMID- 4291227 TI - Two populations of herpes virus virions which appear to differ in physical properties and DNA composition. PMID- 4291228 TI - The iron complex in spinach ferredoxin. PMID- 4291230 TI - Lack of interference in tissue culture between the viruses of canine distemper and infectious canine hepatitis as demonstrated by immunofluorescence. PMID- 4291229 TI - The effect of HeLa cell cytoplasm on the rate of sedimentation of RNA. PMID- 4291231 TI - [Comparative study of the molecular weights of 2 human interferons produced in vitro]. PMID- 4291232 TI - [Study of KB cells infected with type 2 and 3 Myxovirus parainfluenzae and respiratory syncytial virus. II. Cytochemical study]. PMID- 4291233 TI - Histochemical studies on denervation, chemically induced and hereditary forms of myopathies. PMID- 4291234 TI - Comparative biochemistry of myopathies. PMID- 4291235 TI - Effect of temperature and relative humidity on survival of airborne Columbia SK group viruses. AB - Three strains of the Columbia SK (Col-SK) group of viruses [Mengo, Maus Elberfeld (ME), and Col-SK viruses] have been studied in the airborne state. All three strains were found to give identical aerosol decay patterns at 16 or 26 C, when held at the same relative humidity (RH). During the first 5 min of aerosol storage time at 16 C, virus inactivation was RH-dependent, with survival maximal at either high (greater than 80%) or low (less than 5%) RH. After 5 min at 16 C, further inactivation, regardless of RH, was insignificant. At 26 C, the effect on survival of RH between 40 and 60% was even more pronounced than at 16 C, and continued after 5 min through 6 hr. Results of this study indicated that the inactivation of airborne Col-SK group viruses was similar to that of other ribonucleic acid (RNA) viruses, particularly poliovirus. Since members of the Col SK group are picornaviruses, they may well serve as an aerosol model representative of small, ether-resistant, single-stranded RNA viruses. PMID- 4291236 TI - Use of bisulfite in the streptococcal anti-nicotinamide adenine dinucleotidase test. AB - A major drawback in the performance of the streptococcal anti-nicotinamide adenine dinucleotidase test on a large scale has been the hazard involved in the use of cyanide in assaying nicotinamide adenine dinucleotide. The use of bisulfite instead of cyanide in the performance of this test was investigated. The assays obtained with bisulfite parallel closely those obtained with cyanide, and justify the replacement of cyanide by the safer bisulfite reagent. PMID- 4291237 TI - In vitro studies on the antiviral activity of 1, 3-bis(2-chloroethyl)-1 nitrosourea. AB - Chemotherapy experiments carried out in vitro demonstrated that 1,3-bis(2 chloroethyl)-1-nitrosourea (BCNU) was active against lymphocytic choriomeningitis virus and had an equivocal antiviral effect on Semliki Forest, herpes simplex, and vaccinia viruses. No antiviral effect was observed with BCNU against western equine encephalomyelitis, polio, and parainfluenza (HA-1) viruses. Activity of the drug was determined by inhibition of viral-induced cytopathogenic effect in KB or chick embryo cells and by reduction of virus titer in cell culture supernatant fluid. Maximal activity against the viruses was observed when drug and virus were incubated together for 30 min prior to addition to cells; essentially no activity could be demonstrated if BCNU and virus were added to cells with no prior incubation. PMID- 4291238 TI - [Influence of polypeptides upon adrenal cortex secretion in vitro]. PMID- 4291239 TI - Dissociation in two contractile components of the isolated guinea-pig ileum response to angiotensin. PMID- 4291240 TI - Correlations between adenine nucleotide levels and the velocities of rate determining steps in the glycolysis and respiration of intact Ehrlich ascites carcinoma cells. PMID- 4291242 TI - Release of sulfhydryl groups in cytochrome oxidase by ethylenediaminetetraacetic acid. PMID- 4291241 TI - [NAD-dependent glutamate dehydrogenase from repressed and derepressed baker's yeast]. PMID- 4291243 TI - A soluble factor promoting oxidative phosphorylation in particles isolated from Azotobacter vinelandii. PMID- 4291244 TI - Cholinolytics in the treatment of anticholinesterase poisoning. IV. The effectiveness of five binary combinations of cholinolytics with oximes in the treatment of organophosphorus poisoning. PMID- 4291245 TI - Separation of labeled plasma and tissue lipids by thin-layer chromatography. A quantitative methodological study. PMID- 4291246 TI - Separation of plasma angiotensinases by DEAE sephadex A-50 column chromatography. PMID- 4291247 TI - Thymidine and thymidylate kinase, and thymidylate phosphatase in human leukemic leukocytes. PMID- 4291248 TI - Effect of glycyrrhizin on the suppressive action of cortisone on the pituitary adrenal axis. PMID- 4291249 TI - An in vivo assay method for corticotrophin-releasing factor (CRF) in dexamethasone-nembutal treated rats. PMID- 4291250 TI - Purification of corticotrophin-releasing factor (CRF) from posterior pituitary powder of hog origin. PMID- 4291251 TI - Periodate oxidation of glycopeptides from ovalbumin. PMID- 4291252 TI - Intranuclear cisternae resembling structures of the Golgi complex. PMID- 4291253 TI - Purification of serologically active phosphoinositides of Mycobacterium tuberculosis. AB - Glycolipids extracted with pyridine from three strains of Mycobacterium tuberculosis were fractionated. Phosphatidyl inositol, two phosphatidyl inositol dimannosides (A and M), and two phosphatidyl inositol pentamannosides (G and K) were separated and purified by a combination of solvent fractionations and chromatography on silicic acid. In each of these lipids, palmitic and tuberculostearic acids accounted for more than 90% of the total fatty acids. Mole ratios of fatty acid to P were: for phosphatidyl inositol, 2; for G and M, 3; for A and K, 4. Certain mixtures of A or M with G fixed complement with human sera from cases of tuberculosis. Two serologically inactive dimannosides, each containing two fatty acid ester groups per atom of P, were also present. PMID- 4291254 TI - Fatty acid synthesis in cell-free system from rabbit aorta. AB - The objectives of this study were to identify the subcellular fraction responsible for fatty acid synthesis in rabbit aorta and to determine the effect of cholesterol feeding on the system. A method for homogenization of aorta is described which permitted the isolation of subcellular components of aorta, including mitochondria that were morphologically and functionally intact. Mitochondria were identified as the major site of fatty acid synthesis in this tissue. Cofactor requirements and products showed that the synthetic system operates by chain elongation. Mitochondria from atherosclerotic aortas incorporated acetate into fatty acids faster than did mitochondria from control aortas. It is concluded that cholesterol feeding leads to alterations of aortic mitochondrial function and accelerates the fatty acid elongation pathway. PMID- 4291255 TI - Enzymatic synthesis of cytidine diphosphate diglyceride. AB - Evidence is presented for the enzymatic formation of cytidine diphosphate diglyceride in microsomal preparations from guinea pig liver according to the reaction: CTP + phosphatidic acid right harpoon over left harpoon CDP-diglyceride + p-O-P. Conditions have been found in which the incorporation of labeled CTP into CDP-diglyceride is almost entirely dependent upon added phosphatidic acid. The incorporation of CMP into lipid is very slight. A substantial net synthesis of CDP-diglyceride takes place under these conditions. Some properties of the enzyme system are described. PMID- 4291256 TI - Histamine formation in tumor-bearing rats. PMID- 4291257 TI - Multiplication of polyoma virus in iododeoxyuridine (IUDR)-resistant mouse cells in the presence of IUDR. PMID- 4291258 TI - Radiography of the salivary glands, pharynx and larynx. PMID- 4291259 TI - Measurement of dust exposures in the asbestos textile industry. PMID- 4291260 TI - Quantitative X-ray diffraction analysis of crocidolite and amosite in bulk or settled dust samples. PMID- 4291261 TI - Developmental communalities of homologous and non-homologous body joints. PMID- 4291262 TI - [Studies of the regulation of NAD synthesis in the rat liver]. PMID- 4291263 TI - [Study of the biosynthesis of NAD in rat reticulocytes and erythrocytes]. PMID- 4291264 TI - [Anti-poliomyelitic activity in vitro of D-penicillamine]. PMID- 4291265 TI - [Estimation by tracheal test in rats of the intrinsic harmfulness of various dusts and their protective action in regard to quartz. Coal alone and coal-quartz mixtures]. PMID- 4291266 TI - The respiratory dependent swelling of liver mitochondria. PMID- 4291267 TI - [The adrenal cortex and pregnancy]. PMID- 4291268 TI - [Effects of glycyrrhizin on dexamethasone-induced atrophy of the adrenal cortex- histopathological and enzyme histochemical studies]. PMID- 4291269 TI - [Histochemical study on the endocrine function of the islets of Langerhans with special reference to changes in protein-bound disulfide and sulfhydryl groups in B cells]. PMID- 4291270 TI - Effect of RES-active agents on tryptophan pyrrolase activity and endotoxin lethality. PMID- 4291272 TI - [Methods of obtaining clones of Entamoeba histolytica from culture]. PMID- 4291271 TI - Biochemistry of glycolipids of sea urchin gametes. I. Separation and characterization of new type of sulfolipid and sialoglycolipid. PMID- 4291273 TI - [Clinical aspects of the so-called granular cell myoblastoma of Abrikosov]. PMID- 4291274 TI - Genetic variation in responses to repeated administrations of ACTH and hydrocortisone in immature chickens. PMID- 4291275 TI - Effect of cigarette smoke on rabbit corneal cells in vitro. PMID- 4291276 TI - [Localization of the cerebral zone responsible for the symptoms caused by injection into the spinal fluid of peptides with activity resembling that of ACTH and MSH]. PMID- 4291277 TI - [Research on the anti-poliomyelitic activity in vitro of guanidine. XVI. Antagonism by ethanolamine of the anti-polio effect of guanidine]. PMID- 4291279 TI - The morphology of vesicular stomatitis virus (Indiana C) derived from chick embroyos or cultures of BHK21/13 cells. PMID- 4291278 TI - [6 cases of thecoma. Clinical and histological considerations]. PMID- 4291280 TI - The amino acid utilization by phase 1 Bordetella pertussis in a chemically defined medium. PMID- 4291281 TI - The evolution of clinical pharmacology during one lifetime, with a discussion of new methods applicable to some of its problems. PMID- 4291282 TI - Glass-fiber paper chromatography of vitamin E. PMID- 4291283 TI - The effect of portacaval transposition on the inactivation of angiotensin by the canine liver. PMID- 4291284 TI - [Histopathological and histochemical aspects of infection and immunization with B. pertussis. II. Study of the proteins and mucopolysaccharides]. PMID- 4291285 TI - [Tests for para-influenza 3 on slaughterhouse cattle and milking cows from West Berlin herds]. PMID- 4291286 TI - The mofidication of nucleosides and nucleotides. IV. The reaction of semicarbazide with nucleic acids. PMID- 4291287 TI - The direction of in vitro genetic transcription on circular DNA. PMID- 4291288 TI - [Microsomal enzyme activity (C-6-P-ase and NAD-H cytochrome C reductase) in the cirrhotic human liver]. PMID- 4291289 TI - [On inactivation of MHV-3 virus by the intestine of normal mice of various ages]. PMID- 4291290 TI - [Evolution of hepatitis induced with MHV-3 virus in splenectomized mice]. PMID- 4291291 TI - [Study of the inactivation of MHV-3 virus by various segments of the intestine of normal mice and of its tissue components]. PMID- 4291292 TI - [Instrumental study of peripheral circulation in juvenile vascular diseases in conditions of dynamic changes of adrenal cortex activity. I. Stimulation with ACTH]. PMID- 4291293 TI - [Instrumental study of peripheral circulation in juvenile vascular diseases in conditions of dynamic changes of adrenal cortex activity. II. The Liddle effect]. PMID- 4291294 TI - [Dynamic study of adrenal cortex function in patients with arteriopathy. I. Test of adrenal cortex stimulation with ACTH]. PMID- 4291295 TI - Active transport of potassium ion in heart mitochondria. PMID- 4291296 TI - Oral-facial-digital syndrome in a chromosomally normal male. PMID- 4291297 TI - A sensitive assay for infectivity of mengovirus RNA in L cells. PMID- 4291298 TI - The effect of ACTH and corticosteroids on the brain. PMID- 4291299 TI - [The endocrinologic aspects of progressive myoclonic epilepsy]. PMID- 4291300 TI - Adenovirus infections of the conjunctiva and cornea. PMID- 4291301 TI - Cryosurgery of the mouth, nose and throat. PMID- 4291302 TI - Angiofibromas: diagnosis and treatment, including cryosurgery. PMID- 4291303 TI - Electron microscopic observations on multiple polyoma virus-related particles. PMID- 4291304 TI - The role of the bursa-dependent lymphoid tissue in oncogenesis by avian myeloblastosis virus. PMID- 4291305 TI - Effect of 5-fluorouracil on the multiplication of a virulent virus (pseudorabies) and an oncogenic virus (polyoma). PMID- 4291306 TI - Correlation between replication and degradation of cellular DNA in polyoma virus infected cells. PMID- 4291307 TI - Structure of simian virus 40. I. Purification and physical characterization of the virus particle. PMID- 4291308 TI - Structure of simian virus 40. II. Symmetry and components of the virus particle. PMID- 4291309 TI - On the phosphomonoesterase activity of the genus Proteus. PMID- 4291310 TI - [Research on the influence of the activity of the thymus gland during anti perfringens immunization]. PMID- 4291311 TI - [The effect of penicillin "in vitro" on the spores of Cl. perfringens, type A. (Preliminary report)]. PMID- 4291312 TI - Isolation of a bovine strain of Myxovirus para-influenza Type 3 in Australia. PMID- 4291313 TI - A study of procine enteroviruses isolated from swine in the Toronto area. I. Isolation and serological grouping of viruses. AB - A number of enteric viruses isolated from swine in the Connaught Medical Research Laboratories and the Mimico Reformatory herds were grouped serologically and compared with previously described porcine enteroviruses. Four of five antigenic types defined were related to other porcine enteroviruses. The fifth was unrelated to any viruses with which it was compared in this study. PMID- 4291314 TI - Simplified microestimation of fibrinogen and seromucoid in plasma. PMID- 4291315 TI - The newly deposited mineral in cartilage and bone matrix. PMID- 4291316 TI - Phosphohydrolases of a Bacillus subtilis mutant accumulating inosine and hypoxanthine. AB - Although adenine-requiring auxotrophs of Bacillus subtilis accumulate large quantities of inosine or hypoxanthine, or of both, they do not accumulate inosine 5'-monophosphate (IMP). Experiments directed at understanding this phenomenon were conducted with an adenineless auxotroph and with a mutant derived from it which lacked alkaline phosphohydrolase. It was found that B. subtilis contains four different phosphohydrolases. Only one is an extracellular enzyme; it is a 5' nucleotide phosphohydrolase which can be inhibited by addition of CuSO(4) to the medium. Of the three cellular enzymes, only one, an acid phosphohydrolase, cannot attack 5'-nucleotides; this enzyme is not repressed by inorganic phosphate. One of the two remaining surface-bound enzymes is a nonspecific alkaline phosphohydrolase which attacks both 5'-nucleotides and p-nitrophenyl phosphate; this is the only phosphohydrolase that is markedly repressed by inorganic phosphate. The other surface-bound enzyme is a nonrepressible 5'-nucleotide phosphohydrolase with double pH optima: one at neutrality and the other near pH 9.0. The experiments indicate that the absence of IMP in the extracellular broth is due to degradation of internally accumulated IMP to inosine by the cellular 5' nucleotide phosphohydrolase. PMID- 4291317 TI - Release of carbohydrates from sphingoglycolipid by osmium-catalyzed periodate oxidation followed by treatment with mild alkali. AB - The carbohydrate moiety of sphingoglycolipid, after preliminary acetylation, can be released by periodate oxidation catalyzed by a trace amount of osmium tetroxide, followed by alkaline treatment. Cerebroside, lactosyl ceramide, hematoside, globoside, and gangliosides were degraded to yield, respectively, galactose, lactose, sialyl lactose, a tetrasaccharide, and various oligosaccharides containing sialic acid. Oligosaccharides were separated by paper chromatography and paper electrophoresis. The procedure is useful for characterizing micromolar amounts of sphingoglycolipids. PMID- 4291318 TI - A growth factor in corpus luteum powder for goitrogen-fed rats. PMID- 4291319 TI - Hand problems in children. A timetable for management. PMID- 4291320 TI - The experimental disease produced in calves by the J-121 strain of parainfluenza virus type 3. PMID- 4291321 TI - Depot fat mobilization and liver lipogenesis and ketogenesis in ovine pregnancy toxaemia and the effects of corticotrophin administration. PMID- 4291322 TI - [Method of estimation of the corticotropic activity of plasma]. PMID- 4291324 TI - Attempt at experimental production of carcinoma in gastric ulcer. PMID- 4291323 TI - Histochemical studies on the diencephalon of senescent rats. PMID- 4291325 TI - Percutaneous selective catheterization of the hypogastric artery and of its branches. PMID- 4291326 TI - Isolation and characterization of a strain of infectious bovine rhinotracheitis virus associated with enteritis in cattle: isolation, serologic characterization, and induction of the experimental disease. PMID- 4291327 TI - Isolation and characterization of a strain of infectious bovine rhinotracheitis virus associated with enteritis in cattle: comparative developmental study by fluorescent antibody tracing and electron microscopy. PMID- 4291328 TI - Isolation and characterization of a strain of infectious bovine rhinotracheitis virus associated with enteritis in cattle: pathogenesis studies by fluorescent antibody tracing. PMID- 4291329 TI - Pathogenesis of osteopetrosis in chickens. PMID- 4291330 TI - Subcellular distribution of nicotinamide adenine dinucleotidase in the spleen of tuberculous guinea pigs and tuberculous guinea pigs treated with isoniazid. PMID- 4291331 TI - Role of aldosterone in edema formation. PMID- 4291332 TI - [On the neurovirulence test of poliomyelitis-live vaccine. V. A statistical method for the evaluation of the experiment for the comparison of neurovirulence in the monkey]. PMID- 4291333 TI - Subtotal hepatectomy for primary hepatic carcinoma. PMID- 4291335 TI - Passage of mengovirus through the zona pellucida of the mouse morula. PMID- 4291334 TI - Cytochemistry of phosphatases of the sarcoplasmic reticulum. I. Biochemical studies. AB - A microsomal fraction was isolated from rabbit psoas muscle by a modification of Muscatello's method. The fraction contained a Mg-dependent ATPase which had a pH optimum of 7.5. Activity was further stimulated by addition of Na or K or other monovalent cations to the reaction mixture, but synergistic activation by Na and K, and ouabain inhibition, could not be demonstrated. The enzyme hydrolyzed only ATP (adenosine triphosphate) and ITP (inosine triphosphate) at appreciable rates, but Na or K stimulated activity only when ATP was used as substrate. Activity was inhibited by Ca and by low concentrations of Na deoxycholate, and was sensitive to inhibition by thiol group reagents. The enzyme could be distinguished from another enzyme, also present in the fraction, which was Ca-activated, and which exhibited a wider substrate specificity, different pH activation characteristics, lower specific activity, lack of stimulation by Na or K, and less sensitivity to inhibition by deoxycholate and by thiol group reagents. These findings formed the basis for demonstration of the Mg-dependent ATPase in situ. PMID- 4291336 TI - Spectroscopic investigation of rubredoxin and ferredoxin. PMID- 4291337 TI - Effect of epinephrine on the metabolism of the inositol phosphatides in rat heart in vivo. PMID- 4291338 TI - Quantitative evaluation of immunological reactivity of carriers of malignant tumours against foot and mouth disease virus RNA by the complement fixation reaction. PMID- 4291339 TI - Interferon-like inhibitor and lysosomal enzyme induced in mice injected with endotoxin. PMID- 4291340 TI - Polyglucose-protein complexes. PMID- 4291341 TI - Polyglucose-protein complexes. PMID- 4291342 TI - Diseases of the avian leukosis complex. A commentary on the conference deliberations. PMID- 4291343 TI - Investigations of lymphoid leukosis infection in genetically similar chicken populations. PMID- 4291344 TI - Duck hepatitis virus in duck embryo liver cell cultures. PMID- 4291345 TI - Gross and histopathological description of the cranial form of chronic fowl cholera in turkeys. PMID- 4291346 TI - A novel teichoic acid-like polymer from the cell walls of Bacillus coagulans NRS T2007. PMID- 4291347 TI - Pyridine co-enzymes as electron scavengers in irradiated dry proteins. PMID- 4291348 TI - On the diversity of -SH groups in DPNH dehydrogenase and their tentative localization. PMID- 4291349 TI - Effect of coupling factor 3 on oxidative phosphorylation. PMID- 4291350 TI - Membraneous oxidase purification, properties and reaction characteristics. PMID- 4291351 TI - Stoichiometric utilization of adenosine 5'-triphosphate in nicotinate ribonucleotide synthesis from nicotinate and 5-phosphoribosyl-1-pyrophosphate. PMID- 4291352 TI - The conformation of some pyranose moieties in the molecules of alpha-D hexopyranose-1-phosphates, purine and pyrimidine 5'-(alpha-D-pyranosyl pyrophosphates), and mucopolysaccharides. PMID- 4291353 TI - Mechanism for the stimulation in vivo of hepatic gluconeogenesis by glucagon. PMID- 4291354 TI - Some observations on the periodate oxidation of amino compounds. AB - Various aliphatic and aromatic amines are oxidized by sodium metaperiodate and these reactions have been studied quantitatively in acidic, unbuffered and basic media. Significant differences have been observed between the behaviour of aliphatic and aromatic amines. Certain compounds also behaved differently under acidic and basic conditions. These reactions are related to the periodate oxidation of amino acids and, from observations on a number of glycine derivatives, a reaction mechanism is proposed for this process. PMID- 4291355 TI - Some properties of mandelate racemase from Pseudomonas fluorescens. AB - 1. l-Mandelate dehydrogenase and mandelate racemase were partially purified from extracts of Pseudomonas fluorescens A-312 grown in media containing d-mandelate. 2. The activity of mandelate racemase, but not that of l-mandelate dehydrogenase, is greatly stimulated by Mg(2+), Mn(2+), Co(2+) and, though less effectively, by Ni(2+). Other metal ions are inactive or inhibitory. 3. Racemase activity is inhibited by phosphate, fluoride, pyrophosphate and EDTA. The inhibitions by pyrophosphate and EDTA are competitive with respect to the metal ion activator; those by phosphate and fluoride are competitive with respect to the substrate. 4. The addition of Mg(2+) diminishes the Michaelis constant of racemase. 5. The pH optimum of the racemase is at 7.8. The pH-activity curve of the dehydrogenase complex of enzymes has two peaks, at 7.0 and 8.2. 6. The enzymic racemization of d-mandelate is initially faster than that of l-mandelate. 7. The rates of oxidation of related substrates, catalysed by l-mandelate dehydrogenase, are in the decreasing order: l-p-hydroxymandelate; l-3,4-dihydroxymandelate; l-4-hydroxy 3-methoxymandelate. The racemase is active towards d-p-hydroxymandelate but inactive towards d-3,4-dihydroxymandelate and d-4-hydroxy-3-methoxymandelate. Since 4-hydroxy-3-methoxymandelate, and presumably also 3,4-dihydroxymandelate, arising from the metabolism of catechol-amines, have the d-configuration, the enzymes studied cannot be utilized for estimation of the last two acids in urine. PMID- 4291356 TI - The requirement for bivalent cations in formation of nicotinamide-adenine dinucleotide by nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei. AB - 1. The requirement for bivalent cations in catalysis of NAD formation from ATP and NMN in the presence of NMN adenylyltransferase of pig-liver nuclei was studied. Rates of NAD formation in the presence of the activating cations Cd(2+), Mn(2+), Mg(2+), Zn(2+), Co(2+) and Ni(2+) were approximately a linear function of heats of hydration of the corresponding ions. Ba(2+), Sr(2+), Ca(2+), Cu(2+) and Be(2+) did not activate the enzyme; Be(2+) inhibited the reaction in the presence of Mg(2+) and, to a greater extent, in the presence of Ni(2+). 2. Michaelis constants for NAD formation, measured in a coupled assay with NMN adenylyltransferase and alcohol dehydrogenase at pH8.0 and 25 degrees , in the presence of 3mm concentrations of the unvaried reactants, were 88+/-7mum-ATP, 42+/-4mum-NMN and 85+/-4mum-Mg(2+). The results at this pH and at pH7.5 were consistent with mechanisms in which Mg(2+)-ATP complex is a reactant and free ATP a competitive inhibitor. 3. Formation of nicotinamide-hypoxanthine dinucleotide from NMN and ITP in the presence of the transferase was also more rapid with Ni(2+) and Co(2+) than with Mg(2+). PMID- 4291357 TI - Biochemical and pharmacological studies with 1-beta-D-arabinofuranosylcytosine in man. PMID- 4291358 TI - Evidence for a role of adenosine 3',5'-monophosphate in adipose tissue lipolysis. PMID- 4291359 TI - Structure of the cell wall of Micrococcus lysodeikticus. I. Study of the structure of the glycan. PMID- 4291360 TI - Polysaccharides in germination. Occurrence, fine structure, and possible biological role of the pectic araban in white mustard cotyledons. PMID- 4291361 TI - Tadpole collagenase. Preparation and purification. PMID- 4291362 TI - A new intermediate in the metabolism of ethanol. PMID- 4291363 TI - Calcium and manganese interactions in mitochondrial ion accumulation. PMID- 4291364 TI - Beta-aspartyl peptides in enzymatic hydrolysates of protein. PMID- 4291366 TI - The optical and magnetic properties of copper in Chenopodium album plastocyanin. PMID- 4291365 TI - Fluorinated pyrimidines. XXVII. Attempts to determine transcription errors during the formation of fluorouracil-containing messenger ribonucleic acid. PMID- 4291367 TI - Arsenic-lipid complex formation during sugar transport. PMID- 4291368 TI - [The inhibitory effect of Zn2+ on the oxygen-induced biosynthesis of the respiratory enzymes in yeast]. PMID- 4291369 TI - Activation of rat-liver microsomal glucose 6-phosphatase, inorganic pyrophosphatase and inorganic pyrophosphate-glucose phosphotransferase by hydroxyl ion. PMID- 4291370 TI - Reactivity and stability of alcohol dehydrogenase below 0 degrees in alcohol water solvents. PMID- 4291371 TI - Biphasic effects of nucleotides on potassium-dependent phosphatase. PMID- 4291372 TI - An improved method for the estimation of homovanillic acid in human urine. PMID- 4291373 TI - Relationship of ovine contagious ecthyma and ulcerative dermatosis. PMID- 4291374 TI - [ACTH stimulation of corticosteroid biosynthesis by liberation of "bound" 21 deoxypregnene]. PMID- 4291375 TI - Immunofluorescent antibody studies of a murine leukemia virus: comparison of human, bovine and murine systems. PMID- 4291376 TI - Stimulation of the in vitro biosynthesis of corticosteroids by angiotensin II. PMID- 4291377 TI - Chronic hepatic injury following experimental viral hepatitis in the dog. PMID- 4291378 TI - [On corticoid feedback]. PMID- 4291379 TI - [Feed back mechanism of cortisol]. PMID- 4291380 TI - The isolation of the membrane of the toad bladder epithelial cell. PMID- 4291381 TI - Persistence of maternal antibodies to parainfluenza 3 virus. PMID- 4291382 TI - Effect of vitamin D3 on milk yield of thyroparathyroidectomized rats. PMID- 4291383 TI - Octamethylbiguanide perchlorate. PMID- 4291384 TI - A visco-elastic theory of mechanoreceptor adaptation. AB - 1. Physical analysis of two visco-elastic models was performed, to afford a quantitative basis for examination of a theory of slip as applied to mechanoreceptor adaptation. In one model the coupling force between skin tissue and receptor was considered to be purely viscous; in another it was supposed to consist of parallel viscous and elastic forces, representing the properties of a gel.2. Predictions from the models were compared with experimental results from frog and rat skin receptors. Good fits with slope-latency and slope-amplitude curves were obtained, with the adjustment of two constants.3. The excitability changes during long subliminal stimuli showed dynamic and static phases, which developed at different rates as stimulus strength was increased. This behaviour could be explained qualitatively by the more complex model, but quantitative comparisons could not be achieved.4. Treatment of the skin with tissue-destroying enzymes caused changes in stimulus-response relationships consistent with predictions from the models. The effect of the enzymes seemed to be largely on the elastic coupling forces.5. The visco-elastic model offers a satisfactory but not exclusive explanation of certain time- and amplitude-dependent features of mechanoreceptor behaviour and also accounts for a specific delay in mechanical excitation. PMID- 4291386 TI - Relations between chemical structure and biological activity in peptides. PMID- 4291385 TI - The effect of propranalol on the calorigenic response in brown adipose tissue of new-born rabbits to catecholamines, glucagon, corticotrophin and cold exposure. AB - 1. Experiments measuring the rate of oxygen consumption of unanaesthetized new born rabbits and the blood flow in brown adipose tissue of anaesthetized new-born rabbits are described.2. The increase in rate of oxygen consumption caused by I.V. infusion of noradrenaline, adrenaline and isoprenaline (2 mug/kg.min for 10 min) was blocked by propranalol (I.V. 1 mg/kg) but the increase caused by cold exposure was not. A larger dose of propranalol (5 mg) blocked the calorigenic response to cold exposure as well.3. Infusion of glucagon (I.V. 4 mug/kg.min for 10 min) caused a large increase in the rate of the rabbit's oxygen consumption and in blood flow through its brown adipose tissue. These responses, which reached a maximum within 10 min from the start of the infusion, were not blocked by propranalol (1 or 5 mg/kg).4. Infusion of corticotrophin (I.V. 1 i.u./kg.min for 10 min) also caused a large increase in the rate of oxygen consumption of new born rabbits. The response reached a maximum about 20 min from the start of the infusion and it was not blocked by propranalol (5 mg/kg).5. These results support the conclusion that noradrenaline is released at sympathetic endings in brown adipose tissue and that the increase in blood flow caused by noradrenaline is secondary to its metabolic action on the tissue. They also suggest the possibility that glucagon and corticotrophin may act directly on brown adipose tissue and stimulate heat production during cold exposure. PMID- 4291387 TI - Effect of yeast pyruvate decarboxylase on Ehrlich ascites carcinoma in vivo. PMID- 4291388 TI - Intrathymic inoculation of a murine leukaemia virus (Rich). PMID- 4291389 TI - [Iodoventriculography in tumors of the 3rd ventricle]. PMID- 4291390 TI - Isolation of ovine strains of parainfluenza virus serologically related to type 3. PMID- 4291391 TI - [A case of submaxillary benign "granular cell" tumor]. PMID- 4291392 TI - Cardiovascular reactivity of rats during the development of salt hypertension. I. the response to polypeptides. PMID- 4291393 TI - Studies on the mechanism of action of the delta5-3-ketosteroid isomerase from rat adrenal small particles. PMID- 4291394 TI - Fructose diphosphatase from rabbit liver. VII. Tyrosine residues and adenosine monophosphate inhibition. PMID- 4291395 TI - Steroid hydroxylations. V. Intracellular location of 16alpha-hydroxylase and its substrate specificity in sow ovary. PMID- 4291396 TI - Nucleoside phosphonic acids. I. The synthesis of 5'-deoxyuridine 5'-phosphonic acids and derivatives. PMID- 4291398 TI - [Research on seminal nucleotidopyrophosphatase]. PMID- 4291397 TI - Properties of the induced acid phosphatase and of the constitutive acid phosphatase of Euglena. PMID- 4291399 TI - Nephrotoxicity of some vasoactive drugs following selective intra-arterial injection. PMID- 4291400 TI - A simple method for determination of ability of bacteria to inactivate chemotherapeutics using sensitivity disc. PMID- 4291401 TI - Antibiotics and rat diagphragm carbohydrate metabolism. PMID- 4291403 TI - A coat protein from bacteriophage fd. I. Hydrodynamic measurements and biological characterization. PMID- 4291402 TI - Molecular mechanisms of genetic recombination in bacteriophage. VI. A mutant defective in the joining of DNA molecules. PMID- 4291404 TI - Polarity in the histidine operon. PMID- 4291405 TI - Biophysical evidence for linkage of adenovirus and SV40 DNA's in adenovirus 7 SV40 hybrid particles. PMID- 4291406 TI - Studies on the suggested role of an endocrine-specific virus in the aetiology of primary liver cancer. PMID- 4291407 TI - [Tuberculous meningitis. Problems in diagnosis and treatment]. PMID- 4291408 TI - [Anatomical evolution of tuberculous meningitis]. PMID- 4291409 TI - [Physiopathology of suppurative meningitis]. PMID- 4291410 TI - [Evolution and complications of suppurative meningitis]. PMID- 4291411 TI - [Myocardial aortic insufficiency]. PMID- 4291412 TI - [Gastrin]. PMID- 4291413 TI - [Effect of testosterone and anabolic steroids on disturbances of reactive connective tissue formation by thyroid gland hormones and glucocorticoids]. PMID- 4291414 TI - Diagnosis and treatment of pancreatic islet cell adenomas. PMID- 4291415 TI - [Purine-nucleoside phosphorylase activity of the blood and hepatic and splenic tissue of mice during experimental hepatitis caused by MHV virus]. PMID- 4291416 TI - [On the effect of 2,4-dinitrophenol on proteins]. PMID- 4291417 TI - [Phosphoserine phosphatase in the liver and kidney of the chick embryo]. PMID- 4291418 TI - Specific antagonism to the direct and indirect action of angiotensin on isolated guinea-pig ileum. PMID- 4291419 TI - [Study of a line of KB cells permanently infected by myxovirus para-influenzae 3. 3. Proportion of infected and virus-producing cells]. PMID- 4291420 TI - [Influence of potassium perchlorate on urinary excretion of I-127 in prenatal deaf-mutism with the KClO-4 positive test]. PMID- 4291421 TI - [Some aspects of adrenal cortex physiology in the senile age]. PMID- 4291422 TI - Estimation of post-mortem blood barbiturates using Turner's perchloric acid precipitation method combined with thin layer chromatographic isolation. PMID- 4291423 TI - Poisoning by volatile compounds. 3. Hydrocyanic acid. PMID- 4291424 TI - Bilateral Wilms' tumors. PMID- 4291425 TI - Errors in diagnosis in Wilms' tumor. PMID- 4291426 TI - [The gamma-cystography of expansive intracranial processes]. PMID- 4291427 TI - [Influence of sex hormones on urinary phosphatases]. PMID- 4291428 TI - [Articular chondrocalcinosis]. PMID- 4291429 TI - [Disseminated lupus erythematosus in males]. PMID- 4291430 TI - [Rheumatic monoarthritis. Proposed diagnostic criteria]. PMID- 4291431 TI - [Comparative frequency of lumbar osteophytosis, calcifications of rib cartilages and calcifications of the abdominal aorta in subjects with osteoporosis or osteomalacia and in control subjects]. PMID- 4291432 TI - [Multiple tendon calcification disease]. PMID- 4291433 TI - [Diabetes in cirrhosis patients. (Apropos of 50 cases)]. PMID- 4291434 TI - [Glycoregulation disorders in cirrhosis patients]. PMID- 4291435 TI - [Jejunogastric invagination of the afferent loop after gastrectomy]. PMID- 4291437 TI - [Viral meningitis in children. Clinical and biologic diagnosis]. PMID- 4291436 TI - [Therapeutic study of magnesium bromoglutamate in neuropsychiatry]. PMID- 4291438 TI - [Attempt at prevention and treatment of edemas in orthopedic and traumatologic surgery]. PMID- 4291439 TI - [The significance of clinical studies of gastric secretion]. PMID- 4291440 TI - [A new type of pituitary cells: corticotropic cells]. PMID- 4291441 TI - [DNA and RNA content of the liver of mice various phases of experimental hepatitis caused by MHV-3 Craig virus]. PMID- 4291442 TI - Pharmacodynamics of mitral insufficiency in muscular subaortic stenosis. PMID- 4291443 TI - The antigens of vesicular stomatitis virus. 3. Structure and immunogenicity of antigens derived from the virion by treatment with Tween and ether. PMID- 4291444 TI - Herpes simplex neutralizing antibody--quantitation of the complement-dependent fraction in different phases of adult human infection. PMID- 4291445 TI - [Electron spin resonance analysis of the association of manganese ions with trivalent whale myoglobin and horse hemoglobin]. PMID- 4291446 TI - Comparative sedimentation coefficients of RNA extracted from plaque-forming and defective particles of vesicular stomatitis virus. PMID- 4291448 TI - The viral flora of the alimentary tract of chimpanzees. PMID- 4291447 TI - The false-positive hepatic scan. PMID- 4291449 TI - Error of intraperitoneal injections in rats. PMID- 4291450 TI - Extended B-virus anti-body determinations in a closed monkey colony. PMID- 4291451 TI - [Viral hepatitis observed in a Parisian hospital environment (85 cases). I. Clinical and biological study]. PMID- 4291452 TI - [Viral hepatitis observed in a Parisian hospital environment (85 cases). II. Histological study]. PMID- 4291453 TI - [Calcic microscystalline arthritis (pseudo-gout) in a patient with acromegaly]. PMID- 4291454 TI - [Acute aortic and mesenteric ischemic complications during disseminated lupus erythematosus]. PMID- 4291455 TI - [Current evolutive forms of typhoid fever. Apropos of 2 cases]. PMID- 4291456 TI - [An easy method of intestinal retraining in the treatment of gynecologic and endocrinological disorders]. PMID- 4291457 TI - Stimulation of rat adrenocortical cells by glycyrrhizin with special reference to its inhibitory effect on dexamethasone-induced atrophy of the adrenal cortex. PMID- 4291458 TI - [Effect of nicotinamide on the NAD level and the activity of NAD-glycohydrolase in the skeletal muscles and the liver]. PMID- 4291459 TI - [Cytochromoxidase activity of guinea pig organs in anoxia]. PMID- 4291460 TI - Some properties of denatured horse heart cytochrome c. PMID- 4291461 TI - Insulin-like activity of a microbial protease on isolated fat cells. PMID- 4291462 TI - Substrate inhibition effects in the liver alcohol dehydrogenase reaction. PMID- 4291463 TI - Beta-aspartylglycine in urine and enzymic hydrolyzates of proteins. PMID- 4291464 TI - Necrotic enteritis of broiler chickens in western Australia. PMID- 4291465 TI - A microbiological study of bovine conjunctivitis and keratoconjunctivitis. PMID- 4291466 TI - Selenium metabolism. 3. Serum proteins, lipoproteins and liver injury. PMID- 4291468 TI - [Antiviral activity of some guanylhydrazone derivatives]. PMID- 4291467 TI - The specificity of enzymic reactions. Aminoacyl-soluble RNA ligases. PMID- 4291469 TI - [The cytochrome oxidase reaction in some types of normal and pathological hematic cells]. PMID- 4291470 TI - [Protective action of EDTA on inactivation by CCl-4 in vitro of microsome glucose 6-phosphatase]. PMID- 4291471 TI - In vitro aldosterone production by adrenals of normal recipient rats cross circulated with rats with secondary hyperaldosteronism of dietary sodium restriction. PMID- 4291472 TI - Thyroid function during the rebound phase following the discontinuation of antithyroid drugs. PMID- 4291473 TI - Binding of calcium by liver mitochondria: an effect of steroid hormones in vitamin D-depleted and parathyroidectomized rats. PMID- 4291474 TI - Lactic dehydrogenase. X. A re-evaluation of the effects of pH upon the kinetics of the reaction. PMID- 4291475 TI - Biosynthesis of gibberellins. II. Enzymic cyclization of geranylgeranyl pyrophosphate to kaurene. PMID- 4291476 TI - Biochemical investigation of an unusual case of glycogenosis. PMID- 4291477 TI - Enteritis necroticans in Uganda. PMID- 4291478 TI - The effect of phenobarbital on drug metabolic enzyme activity, ultrastructure and growth of a "minimal deviation" hepatoma (Morris 7800). PMID- 4291479 TI - [Pharmacologic properties of the 1(p-hydroxyphenyl)2-phenyl-3-hydroxy-4-n-butyl-5 pyrazolinonate of 2-beta-hydroxyphenethylamino-pyridine and research on its biochemical action]. PMID- 4291480 TI - Effect of noradrenaline on phosphatase activity in synaptic membrane of the rat brain. PMID- 4291481 TI - Radiocarbon dating of bone. PMID- 4291482 TI - [Cerebrospinal fluid changes in brain tumors]. PMID- 4291483 TI - A chemical approach to the problem of cellular malignancy in tumours of the nervous system. PMID- 4291484 TI - Cytoplasmic oxidation activity in cell division processes in the tumours of the nervous system and in their tissue cultures. PMID- 4291485 TI - Isolation and characterization of an enterovirus from baby chicks having an enteric infection. I. Isolation and pathogenicity. PMID- 4291486 TI - Compared antibodies for Rous sarcoma virus in chicken serum and egg yolk with the metabolism inhibition test. PMID- 4291487 TI - Isolation and characterization of an enterovirus from baby chicks having an enteric infection II. Physical and chemical characteristics and ultrastructure. PMID- 4291488 TI - The pathway of synthesis of mammary-gland nicotinamide-adenine dinucleotide. PMID- 4291489 TI - Activation of liver pyruvate kinase by fructose 1,6-diphosphate. PMID- 4291490 TI - Inhibition of sucrose phosphatase by sucrose. AB - 1. Partially purified sucrose phosphatase from immature stem tissue of sugarcane is inhibited by sucrose. The enzyme was also inhibited by maltose, melezitose and 6-kestose but not by eight other sugars, including glucose and fructose. 2. The relative effectiveness of sucrose, maltose and melezitose as inhibitors is different for sucrose phosphatase from different plants. 3. The inhibition of the sugar-cane enzyme by sucrose was shown to be partially competitive. The K(i) for sucrose is about 10mm. 4. Melezitose is also a partially competitive inhibitor of the enzyme but the inhibition by maltose is probably mixed. 5. The possibility that sucrose controls both the rate of accumulation of sucrose in stems of sugar cane and sucrose synthesis in leaves by inhibiting sucrose phosphatase is discussed. PMID- 4291491 TI - Purification and properties of crystalline 3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. AB - 1. The purification and crystallization of 3-hydroxybutyrate dehydrogenase from extracts of Rhodopseudomonas spheroides is described. 2. The molecular weight was calculated to be 85000 by sedimentation equilibrium. 3. Although the enzyme is stable at 0-4 degrees , dilute solutions are rapidly inactivated at 37 degrees ; NADH(2) or Ca(2+) ions prevent this inactivation. 4. The enzyme is extremely sensitive to mercurials, but can be protected by NADH(2) or Ca(2+) ions. 5. From studies on p-hydroxymercuribenzoate binding it is estimated that the enzyme contains 5-6 moles of rapidly reacting thiol groups/mole. 6. d-Lactate and dl-2 hydroxybutyrate are competitive inhibitors of d-3-hydroxybutyrate oxidation. 7. The properties of the crystalline enzyme are compared with those of 3 hydroxybutyrate dehydrogenase preparations from other sources. PMID- 4291492 TI - Glycogen metabolism in Novikoff ascites-hepatoma cells. AB - A study of the enzymes of the glycogen pathway in Novikoff ascites hepatoma shows that glycogen synthetase has the lowest activity and that the tumour contains no high-K(m) soluble glucokinase. However, incubation of tumour cells with metabolizable sugars in vitro, or intraperitoneal administration of glucose into the tumour-bearing rat, results in glycogen accumulation by the tumour cells. Glycogen synthesis in the tumour is supported by aerobically produced ATP but is decreased anaerobically and by uncouplers of oxidative phosphorylation. Absence of P(i) from the incubation medium increases glycogen synthesis and decreases glycolysis. The optimum temperature for glycogen synthesis is 37 degrees . The capacity of the intact tumour cell to degrade deposited glycogen is low, but is accelerated by 2,4-dinitrophenol. Tumour homogenates prepared after osmotic shock do not incorporate [(14)C]glucose into glycogen. The glucose moiety of glucose 1 phosphate and of UDP-glucose is incorporated into glycogen by the homogenates and the incorporation of glucose 1-phosphate is greatly enhanced by AMP. Glucose 6 phosphate is a poor precursor of glycogen in the homogenate system, probably because it inhibits activation of phosphorylase b by AMP. PMID- 4291493 TI - Periodate oxidation of sperm-whale myoglobin and the role of the methionine residues in the antigen-antibody reaction. AB - 1. Oxidation of sperm-whale metmyoglobin and its apoprotein with periodate has been investigated under various conditions of pH and temperature to find those under which the reagent acted with specificity. 2. At pH6.8 and 22 degrees consumption of periodate ceased in 3(1/2)hr. at 43 moles of periodate/mole of myoglobin. The two methionine residues, the two tryptophan residues, the three tyrosine residues and two histidine residues were oxidized; serine increased in the hydrolysates from 6 to 9 residues/mol. 3. At pH5.0 and 22 degrees , consumption levelled off in 4(1/2)hr. at 26 moles of periodate/mole of myoglobin and resulted in the modification of the two methionine residues, the two tryptophan residues, the three tyrosine residues and two histidine residues; serine increased from 6 to 7 residues/mol. and, also, ferrihaem suffered considerable oxidation. 4. Oxidation at pH5.0 and 0 degrees resulted at completion (4hr.) in the consumption of 22 moles of periodate/mole of myoglobin and in the modification of the methionine, tyrosine and tryptophan residues. Spectral studies indicated oxidation of the haem group. This derivative reacted very poorly with rabbit antisera to MbX (the major component no. 10 obtained by CM-cellulose chromatography; Atassi, 1964). 5. Oxidation of apomyoglobin at pH5.0 and 0 degrees was complete in 4hr. with the consumption of 7.23 moles of periodate/mole of apoprotein. The rate of oxidation in decreasing order was: methionine; tryptophan; tyrosine; and after 7hr. of reaction the following residues/mol. were oxidized: methionine, 2.0; tryptophan, 1.6; tyrosine, 0.99. No peptide bonds were cleaved. Metmyoglobin prepared from the 7hr.-oxidized apoprotein showed that the reactivity with antisera to MbX had diminished considerably. 6. Milder oxidation of apoprotein (2 molar excess of periodate, pH5.0, 0 degrees , 2hr.) resulted in the modification of 1.66 residues of methionine/mol. Metmyoglobin prepared from this apoprotein was identical with native MbX spectrally, electrophoretically and immunochemically. It was concluded that the methionine residues at positions 55 and 131 were not essential parts of the antigenic sites of metmyoglobin. PMID- 4291494 TI - Properties of substituted 2-trifluoromethylbenzimidazoles as uncouplers of oxidative phosphorylation. AB - 1. The activity of 25 substituted 2-trifluoromethylbenzimidazoles in uncoupling oxidative phosphorylation by rat-liver mitochondria has been compared. 2. For halogen- or mixed-halogen- and alkyl-substituted analogues, uncoupling activity was proportional to the acidity of the imidazole -NH group. Tetrachloro-2 trifluoromethylbenzimidazole was the most active (50% uncoupling of oxidative phosphorylation at 7.9x10(-8)m, pK5.04). Nitro-substituted analogues were less active than predicted from pK considerations or from partition-coefficient measurements. 3. Introduction of an -NH(2) or -CO(2)H substitutent caused a loss of uncoupling activity, as did alkylation at position 1 of the imidazole ring. 4. Benzimidazoles active as uncouplers stimulated mitochondrial adenosine triphosphatase but not all stimulated the oxidation of succinate in the absence of a phosphate acceptor. 5. 4,5-Dichloro-2-trifluoromethylbenzimidazole inhibited the succinate-oxidase system at about the same concentration required for uncoupling (0.52mum for 50% inhibition of both activities) and the site of this inhibition appears to lie between succinate dehydrogenase and cytochrome b. PMID- 4291495 TI - The distribution of cytochrome-oxidase activity in rabbit brain. AB - 1. The cytochrome-oxidase activity in eleven structures of the rabbit brain has been investigated. 2. Kinetic data suggest that the same enzyme occurs in all brain structures but that the activity on a tissue-weight basis differs from structure to structure, being in general higher in the phylogenetically newer structures. 3. When the kinetic data are related to cell density (as measured by DNA concentration) all the neuron-containing structures of the cerebrum and brain stem show the same activity but the corpus callosum and the cerebellum show much less. 4. A special study was made of the distribution of activity and cell density within the diencephalon. 5. The results suggest that all neurons in the cerebrum and brain stem have a similar cytochrome-oxidase activity, which is about 80 times that of glia, and that the cerebellum is relatively richer in glia or that it contains neurons with a much lower cytochrome-oxidase activity, or both. PMID- 4291496 TI - [The value of radioactive lymphography in the treatment of cancers of the testis]. PMID- 4291497 TI - Mechanisms of viral carcinogenesis. PMID- 4291498 TI - Disturbances of trigeminal and facial nerves. PMID- 4291499 TI - Endocrine effects on plasma calcium in parathyroidectomized rats. PMID- 4291501 TI - [On an unknown N-free glycerophosphatide from green leaves of Spinacia oleracea]. PMID- 4291500 TI - [On the modification of lipid metabolism in adrenal glands of rats. II. Studies following stimulation with ACTH]. PMID- 4291502 TI - Studies on tissue specificity of interferon. PMID- 4291503 TI - Antibiotic inhibition and binding studies with a group A streptococcal L-form. PMID- 4291505 TI - Intranuclear inclusion bodies in the intestinal epithelium of pig foetuses experimentally infected with porcine adenovirus. PMID- 4291504 TI - Cytotoxicity of silica and liberation of lysosomal enzymes. PMID- 4291506 TI - Necrotizing clostridial colitis. PMID- 4291507 TI - Release of enzymes from the liver. PMID- 4291509 TI - The reduction of ubiquinone by sarcosine dehydrogenase system. PMID- 4291508 TI - Liver glucose-6-phosphatase and carbohydrate metabolism in childhood leukemia. PMID- 4291510 TI - Viral depuration of the Northern quahaug. AB - A study was conducted to evaluate critically the feasibility of using the self cleansing mechanism as a practical means to obtain virus-free shellfish. Two systems supplied with fresh running seawater, three strains of human enterovirus and the Northern quahaug, were used as working models. Preliminary experiments in the experimental system under arbitrarily selected conditions showed that depuration of poliovirus-polluted quahaugs could be achieved by the method used for the Eastern oyster. The factors affecting viral depuration studied so far included: (i) initial concentration of shellfish pollution; (ii) temperature of seawater; and (iii) salinity of seawater. It was shown that purification of the lightly polluted shellfish was achieved sooner than of the heavily polluted ones. The efficiency of viral depuration was roughly a function of the water temperature within the range tested (5 to 20 C). Reduction of salinity to 50 to 60% of the original level stopped this process completely, but 25% reduction in salinity did not affect significantly the rate of depuration. Preliminary study in the pilot system showed that viral depuration in the large tank appeared to be equally as efficient as that in the small experimental tanks under the particular conditions. PMID- 4291511 TI - Characterization of clostridia by gas chromatography. I. Differentiation of species by cellular fatty acids. AB - Fatty acids of 41 strains representing 13 species of Clostridium were extracted directly from whole cells and examined as methyl esters by gas-liquid chromatography. Both visual and quantitative comparisons of the resulting chromatograms for the presence and relative amounts of large major peaks allowed rapid differentiation of C. perfringens, C. sporogenes, and C. bifermentans from each other and from 10 other species. Each of the three former species possessed a different characteristic fatty acid methyl ester profile that was exhibited by all strains tested within the respective species. Culture age and growth media influenced the relative proportions of certain of the acids, but such differences did not limit species differentiation. PMID- 4291512 TI - Cytopathic effect of mumps and other viruses in guinea pig heart cells. PMID- 4291514 TI - The influence of mast cell depletors on vascular reactivity in the mesenteric microcirculation. PMID- 4291513 TI - Use of pharmacologic antagonists to evaluate humoral regulation of the microcirculation. PMID- 4291515 TI - Influence of vasoexcitor-pressor drugs on microvascular injury in shock. PMID- 4291516 TI - Induced hyperlipemia and the dissemination of tumor cells. PMID- 4291517 TI - The action of vasoactive substances on the microvasculature of the hamster cheek pouch. PMID- 4291518 TI - Attempts to purify and identify an acetylcholine-releasing substance from neural tissue. PMID- 4291520 TI - [The sanitary problems caused by sea-mussels. 3. Poliomyelitis virus concentration capacity]. PMID- 4291519 TI - [Oxidation of glucuronosides with periodate and the determination of urinary pregnanediol]. PMID- 4291521 TI - [Persistence of the genome of the Rous virus in hamster cells converted in vitro, and action of the inactivated Sendai virus on its transmission to chicken cells]. PMID- 4291522 TI - A structural gene for the DPN-specific glutamate dehydrogenase in Neurospora. PMID- 4291523 TI - Asthma caused by FD&C approved dyes. PMID- 4291525 TI - An automated method for the determination of urinary 17-hydroxycorticosteroids. PMID- 4291524 TI - Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay. PMID- 4291526 TI - Concentration of bromine-82 in the thyroid gland of rats. PMID- 4291528 TI - Differences in the biological and immunological activities of human chorionic gonadotrophin after the removal of sialic acid by enzymic hydrolysis. PMID- 4291527 TI - A comparison between the handling of iodine and technetium by the thyroid gland of the rat. PMID- 4291529 TI - A new in vitro assay for thyroid-stimulating hormone. PMID- 4291530 TI - Electrophoretic characterization and fractionation of polyoma virus DNA. PMID- 4291531 TI - Ionic antagonism and the cholinergic activation induced by polymyxins on the heart. PMID- 4291532 TI - [Decreased response of the blood pressure to synthetic angiotensin II in rats with CCl-4-induced liver cirrhosis]. PMID- 4291533 TI - Structures of the polymyxins A and the question of identity with the polymyxins M. PMID- 4291534 TI - Measurement of angiotensin II in blood. PMID- 4291536 TI - Effect of ACTH on the behavior of glycogen and ribonucleic acid in the liver of guinea pigs with experimental scurvy. PMID- 4291535 TI - [Specificity of nitrate reductase induction by Bacillus cereus]. PMID- 4291537 TI - Pituitary irradiation for Cushing's syndrome. PMID- 4291538 TI - [Purine synthesis in the mouse hepatoma and liver tissue]. PMID- 4291539 TI - [Cytologic diagnosis of the Paget type of breast cancer]. PMID- 4291540 TI - [Cytologic observations on the hyperplastic adrenal cortex in man]. PMID- 4291541 TI - [Effects of cervical sympathectomy on rat pituitary lobes]. PMID- 4291542 TI - [Contributions to the role of ADH in the regulation of ACTH secretion]. PMID- 4291543 TI - [On species specificity of the morphokinetic effect of the adrenal cortex]. PMID- 4291544 TI - [Corticoid secretion by the adrenal cortex in anesthetized and waking dogs]. PMID- 4291545 TI - [Pituitary-adrenal function in the patients with bronchial asthma]. PMID- 4291546 TI - [Mammary thermograms]. PMID- 4291547 TI - [Tumor of the accessory salivary glands]. PMID- 4291548 TI - [On a case of Abrikosov's tumor of the tongue]. PMID- 4291549 TI - Postnatal changes of NAD-diaphorase and succinic dehydrogenase in the spinal cord of the cat. PMID- 4291550 TI - [Association of hyperthyroidism with an islet-cell adenoma. Physiopathologic considerations]. PMID- 4291551 TI - [Dynamic analysis of the stomach epithelium - 3H-thymidine autoradiographic study]. PMID- 4291553 TI - Inhibition of the respiratory chain by zinc ions. PMID- 4291552 TI - Effects of different classes of drugs on the passive cutaneous anaphylaxis. PMID- 4291554 TI - Variation in inhibitor sensitivity of NADH-menadione reductase from mitochondria. PMID- 4291555 TI - Sedimentation properties of the enzymes of the histidine B gene. PMID- 4291556 TI - Specificity of ox brain triphosphoinositide phosphomonoesterase. PMID- 4291557 TI - The influence of fructose and its metabolites on ethanol metabolism in vitro. AB - 1. Fructose caused an increase in the rate of ethanol oxidation by rat-liver slices, and d-glyceraldehyde was found to have a similar effect. 2. Addition of glycerol lowered the rate of ethanol oxidation if the incubation medium contained fructose and ethanol, but no such effect was found if it contained glucose and ethanol. 3. The formation of glycerol by the slices during incubation and the concentration of alpha-glycerophosphate in the slices were highest in medium containing fructose and ethanol. 4. In experiments without ethanol in the incubation medium, fructose strongly increased the pyruvate concentration, which resulted in a decrease of the lactate/pyruvate concentration ratio. Addition of ethanol to the medium resulted in a marked decrease in pyruvate concentration. 5. Oxygen consumption is greater in slices incubated in medium containing fructose and ethanol than in slices incubated in medium containing glucose and ethanol. PMID- 4291559 TI - The chemical nature of the products obtained by the action of cabbage-leaf phospholipase D on lysolecithin: the structure of lysolecithin. AB - 1. Lysolecithin, prepared by the action of snake-venom phospholipase A on ovolecithin, when incubated with Savoy-cabbage phospholipase D, in the presence of Ca(2+) ions, gave two degradation products (designated A and B) in the form of their calcium salts. 2. These calcium salts were separated quantitatively by solvent fractionation and converted into the corresponding sodium salts. 3. Substance B proved to be a lysophosphatidic acid of conventional structure (1 monoacyl-l-3-glycerophosphoric acid). When the phosphate group was removed by means of prostatic acid phosphomonoesterase, a 1-monoglyceride was formed quantitatively. Alkaline hydrolysis gave the theoretical yield of l-3 glycerophosphate. 4. Substance A, on the other hand, had all the properties expected for a cyclic phosphate of a 1-monoglyceride. It was unaffected by phosphomonoesterase. On alkaline hydrolysis, the acyl group was removed and ring opening of the presumed cyclic phosphate group gave an approximately equimolar mixture of 2- and l-3-glycerophosphates. 5. The structures of substances A and B confirm lysolecithin as 1-monoacyl-l-3-glycerylphosphorylcholine. PMID- 4291558 TI - The incorporation of cytidine 5'-monophosphate and other ribonucleotides by an enzyme preparation from rat-liver microsomes. AB - 1. An enzyme preparation from rat-liver microsomes incorporated all four ribonucleotides from the corresponding triphosphates into ribosomal RNA. The reaction was Mn(2+)-dependent, but UMP incorporation also occurred in the presence of Mg(2+). 2. The incorporation of any one ribonucleotide was inhibited by the presence of the other three ribonucleoside triphosphates and by denatured DNA. 3. The product of the reaction consisted of short chains of homopolymer attached to the primer ribosomal RNA. 4. ;Soluble' RNA, synthetic polyribonucleotides, and oligoribonucleotides were also effective primers for CMP incorporation. 5. When phosphodiesterase-treated ;soluble' RNA was the primer, CMP was incorporated into positions usually occupied by the normal terminal trinucleotide sequence of intact ;soluble' RNA, but the enzyme did not synthesize a specific terminal sequence consisting of a defined number of CMP residues. PMID- 4291560 TI - Generation of extramitochondrial reducing power in gluconeogenesis. AB - 1. Kidney-cortex slices incubated with pyruvate formed glucose and lactate in relatively large and approximately equimolar quantities. The formation of these products involves two exclusively cytoplasmic NADH(2)-requiring reductions, catalysed by lactate dehydrogenase and triose phosphate dehydrogenase. From the rates of glucose and lactate formation it can be calculated that over 1000mu moles of NADH(2) must have been produced in the cytoplasm/g. dry wt. of tissue/hr. 2. When lactate is a gluconeogenic precursor the required NADH(2) is generated in the cytoplasm, but, when a substrate more highly oxidized than glucose, such as pyruvate, is the precursor, there is no direct cytoplasmic source of NADH(2). Quantitative data on the fate of pyruvate are in accord with the conclusion that the NADH(2) was primarily formed intramitochondrially by the dehydrogenases of cell respiration, with pyruvate as the major substrate. 3. Similar observations and conclusions apply to experiments with mouse-liver slices incubated with pyruvate, serine or aspartate. 4. Addition of ethanol, which increases the formation of NADH(2) in the cytoplasm, increased the formation from pyruvate of lactate but not of glucose. 5. In view of the low permeability of mitochondria for NAD and NADH(2) it must be postulated that special carrier mechanisms transfer the reducing equivalents of intramitochondrially generated NADH(2) to the cytoplasm. Reasons are given in support of the assumption that the malate-oxaloacetate system acts as the carrier. 6. Various aspects of the generation of reducing power and its transfer from mitochondria to cytoplasm are discussed. PMID- 4291562 TI - Preparation of enriched fractions from cerebral cortex containing isolated, metabolically active neuronal and glial cells. AB - 1. A procedure has been developed for the separation of intact metabolically active neuronal and glial cells in bulk from rat cerebral cortex. Separation depended on dispersion of the tissue in a Ficoll medium followed by centrifugation on a discontinuous Ficoll gradient. Up to 1.5x10(7) neuronal cells could be collected from 12 brains within 3hr. The morphological appearance of these cells seemed good, and the fraction was 8.5-fold purified in terms of dry weight. Average dry weight per neuron was 2300mumug. Maximum glial contamination of the neuronal fraction was 11% as determined by carbonic anhydrase measurements. The glial fraction was free from neurons but contained various subcellular contaminants. 2. Concentrations of nucleic acids, phospholipid, protein and phosphoprotein were determined in the separated fractions. The neuronal fraction was richer than the glial in all except phospholipid. Succinate dehydrogenase was equally distributed between neurons and glia but the neuronal fraction was 1.8-fold enriched in cytochrome oxidase. 3. Measurement of respiration by the cells showed an endogenous uptake of 117mmumoles of oxygen/mg./hr. in neurons, and 173mmumoles of oxygen/mg./hr. in glia. Addition of substrate at 10mm stimulated uptake to similar values in both fractions. With glucose it was 390, with pyruvate 355, and with glutamate 215mmumoles of oxygen/mg./hr. This represented a larger stimulation of neuronal than of glial respiration compared with the basal level. 4. Respiration in cell suspensions was 70-80% of that of slices, whereas fractionated tissue homogenates had respiratory rates of only one-third those of the cell suspensions. Lactate dehydrogenase content of cell suspensions was maintained during gradient centrifugation and washing. 5. The possible uses of isolated cell preparations are discussed. PMID- 4291561 TI - Aspects of the development of flight-muscle sarcosomes in the sheep blowfly, Lucilia cuprina, in relation to changes in the distribution of protein and some respiratory enzymes during metamorphosis. AB - 1. Changes in the amounts and distribution of protein and respiratory enzymes have been estimated during the life cycle of the fly Lucilia cuprina. 2. The fully fed larva contains about 7mg. of protein, the pupa and newly emerged fly about 4mg., and the mature adult about 3mg. 3. There are two periods of incorporation of protein into particles at the expense of the soluble protein; the first, immediately after pupation, may store protein (0.5mg./insect) for use in adult development; the second, over the period of emergence, was due mainly to the development of the thoracic mitochondria of the adult (0.7mg./insect). 4. In the thorax, cytochrome c oxidase and the dehydrogenases for glycerophosphate, isocitrate (NAD-dependent), succinate and malate appeared initially in small particles (less than 1mu in diameter). 5. In adult development these enzymes were redistributed so that in the mature fly most of the activity was present in larger particles (1-10mu in diameter). 6. During this redistribution the specific activity (mul. of oxygen/hr./mg. of protein) of glycerophosphate dehydrogenase in the small particles was 690 at 1(1/2) days before emergence, 955 at emergence and 980 at 7 days after emergence; the corresponding values for the large particles were 164, 760 and 1220. 7. In the mature fly the highest specific activities (mul. of oxygen/hr./mg. of protein) estimated were: glycerophosphate dehydrogenase 1380, isocitrate dehydrogenase (NAD-dependent and requiring ADP and Mg(2+)) 408, succinate dehydrogenase 122, malate dehydrogenase 190, and cytochrome c oxidase 1360. 8. The results are considered in relation to the development of the flight-muscle sarcosomes. PMID- 4291563 TI - Effect of disulfiram (tetraethylthiuram disulfide) on mitochondrial oxidations. PMID- 4291564 TI - Tissue and subcellular distribution of mammalian aldehyde-oxydizing capacity. PMID- 4291565 TI - The influence of the beta-sympathicolytic agent propranolol on glycogenolysis and glycolysis in muscle, brain and liver of white mice. PMID- 4291566 TI - Effect of salt solutions on glycogen phosphorylase. A possible role of the phosphoryl group in phosphorylase a. PMID- 4291567 TI - Mammalian alpha-acetylglucosaminidase. Enzymic properties, tissue distribution, and intracellular localization. PMID- 4291568 TI - The structure of triphosphoinositide from beef brain. PMID- 4291569 TI - The distribution of tritium in fatty acids synthesized from tritiated glucose and tritiated water by rat adipose tissue. PMID- 4291570 TI - Fatty acid biosynthesis. 3. Intracellular site of enzymes in lactating-rabbit mammary gland. PMID- 4291571 TI - The incorporation of radioactive phosphorus into individual liver phosphatides of rats. PMID- 4291572 TI - Phospholipid metabolism in mitochondria and microsomes of rabbit liver during development. PMID- 4291573 TI - The reaction of glyceraldehydephosphate dehydrogenase with NAD+. PMID- 4291574 TI - Mercury-induced reversible increase in 2,3-diphosphoglycerate phosphatase and concomitant decrease in mutase activity of animal phosphoglycerate mutases. PMID- 4291575 TI - The extracellular nuclease activity of Micrococcus sodonensis. I. Isolation and purification. PMID- 4291576 TI - The extracellular nuclease activity of Micrococcus sodonensis. II. Characterization and mode of action. PMID- 4291577 TI - Sex differences in the metabolism of phosphatidyl cholines in rat liver. PMID- 4291578 TI - Endogenous hepatic ketogenesis. Cofactor requirements. PMID- 4291579 TI - Inhibition of phosphatidic acid phosphatase by palmitoyl-coA. PMID- 4291580 TI - The biosynthesis of glycerides and glycerophosphatides by rabbit reticulocytes. PMID- 4291581 TI - Reduction of incubation time in citric acid fermentation by vermiculite. PMID- 4291582 TI - Connective tissue degradation and distensibility characteristics of the non living heart. PMID- 4291583 TI - [Urinary excretion of pregnanetriol in various internal diseases]. PMID- 4291584 TI - [Clinical studies of diabetes insipidus]. PMID- 4291585 TI - Thin-layer chromatography on buffered silica gel in the analysis of sugars in acid hydrolysates. PMID- 4291586 TI - Cytomegalic inclusions in animals in South-West Rumania. PMID- 4291587 TI - Experimental infection of pigs with 2 strains of porcine adenovirus. PMID- 4291588 TI - Experimental infectious canine hepatitis. 3. Histological and immunofluorescence studies of the brain of infected dogs. PMID- 4291589 TI - High-energy phosphate level and cytochrome c linked enzymes activity in some internal organs of sheep with lower phagocytic activity of the reticulo endothelial system. PMID- 4291590 TI - Sensitivity of streptomycetes to antibiotics as a taxonomic character. PMID- 4291591 TI - The assay of catecholamines released into the circulation of the guinea-pig by angiotensin. PMID- 4291593 TI - Chemiosmotic hypothesis of oxidative phosphorylation. PMID- 4291594 TI - Neuraminidase activity of a bovine strain of parainfluenza 3 virus. PMID- 4291595 TI - Effect of chlordiazepoxide on eosinopenia of stress in rabbits. PMID- 4291592 TI - [On the biochemistry of so-called cytostatic side effects; comparative studies. 2. Anaerobic and aerobic glycolysis as well as respiration in the intestinal mucosa, testis and liver following Trenimon, Velbe and Natulan administration]. PMID- 4291596 TI - Effect on the infectivity of various viruses by the intestinal factor of normal mice which inactivates murine hepatitis virus. PMID- 4291597 TI - Effect of prolonged exercise on platelet adhesiveness. PMID- 4291598 TI - [Effect of iodized oil emulsions on the subarachnoid space]. PMID- 4291599 TI - Effect of single injections and intravenous infusions of noradrenalin and hypertension on the lelectrocardiographic pattern of dog in shock. PMID- 4291600 TI - [Differential diagnosis and therapeutic aspects in bilateral traumatic conditional facial and abducens paralysis]. PMID- 4291601 TI - [Neurological syndrome as a remote effect of a malignant tumor (Ammon's horn sclerosis in bronchial carcinoma]. PMID- 4291602 TI - Effect of oestrogen on adrenal ascorbic acid content in the rat. PMID- 4291603 TI - Effect of hexadimethrine bromide on adrenal corticosterone secretion in the rat. PMID- 4291604 TI - [Contribution to the problem of hormone treatment in children with nodding spasms]. PMID- 4291605 TI - [Contribution to "lymphocytic encephalomeningitis]. PMID- 4291606 TI - [Role of tyrosine in the catalytic activity of fructosediphosphatase of the rabbit liver]. PMID- 4291607 TI - [Desensitization to allosteric regulation of fructosediphosphatase of the rabbit liver by treatment with diazobenzene sulfonic acid]. PMID- 4291608 TI - [Action of acetyl imidazole on the catalytic activity of fructosediphosphatase of the rabbit liver]. PMID- 4291609 TI - [Desoxyribonuclease I activity of the hepato-splenic and cerebral tissue of rats during experimental infection with encephalomyocarditis virus]. PMID- 4291610 TI - [Experimental premisses to the introduction of I-131 labeled lipiodol "UF", in endosplenic administration, in the diagnosis and therapy of hepatic neoplasms]. PMID- 4291611 TI - Propagation of porcine cytomegalic inclusion disease virus in cell cultures. Preliminary report. AB - The successful propagation of porcine cytomegalic inclusion disease virus (inclusion-body rhinitis virus) in primary pig lung cell cultures is reported. CID virus was carried through five passages in cell cultures with cytopathic affects appearing from 11 to 18 days post-inoculation. Four pigs inoculated with infected cell culture fluids from the second cell culture passage remained clinically normal. Two, however, had typical inclusion bodies in the glands of the nasal mucosa when examined three weeks post-inoculation. The progressive cytopathic effect produced and the inclusion bodies formed by this strain of porcine CIDV are described. These inclusion bodies appeared to be similar to those formed by cell culture-propagated cytomegaloviruses of man, mouse and guinea pig. PMID- 4291612 TI - Influence of the spleen and thymus on immune responses in ageing mice. PMID- 4291613 TI - [Autochthonous epidemic vertigo in Franconia with antobodies against tick-borne spring-summer meningoencephalitis (FSME-virus)]. PMID- 4291614 TI - [Contribution to the function of the adrenal cortex in dystrophia myotonica]. PMID- 4291616 TI - [Encephalitis associated with herpes simplex virus infections]. PMID- 4291615 TI - [Contribution to the clinical aspects and morphology of hypophyseal adenomas]. PMID- 4291617 TI - [Differential blood pressure effects of hypertensin infusions into the portal vein and vena cava in dogs]. PMID- 4291618 TI - Histochemical study of beagle aorta. PMID- 4291619 TI - Automated test for milk phosphatase. PMID- 4291620 TI - Vesicular stomatitis virus--the relationship between some strains of the Indiana serotype. PMID- 4291621 TI - Malignant catarrhal fever in East Africa 3. Neutralizing antibody in free-living wildebeest. PMID- 4291622 TI - A histochemical study with Fasciola hepatica. PMID- 4291624 TI - [Mucoepidermoid carcinoma of the small intestine]. PMID- 4291623 TI - [Cytostatic therapy of hemoblastoses and malignant tumors with a methylhydrazine derivative]. PMID- 4291625 TI - [The corpora cavernosa penis as a site for secondary tumor seeding in cancer of the rectum]. PMID- 4291626 TI - [White atrophy (Atrophia alba)]. PMID- 4291627 TI - The results of cytology in 1000 patients with pulmonary malignancy. PMID- 4291628 TI - Chromosome studies on cultured tumors of nervous tissue origin. PMID- 4291629 TI - Tetracycline fluorescence and enzyme histochemistry on early radiation damage in mouse kidney. PMID- 4291630 TI - Rabbit beta cell ultrastructure and insulin radio-immunoassay in experimental subdiabetes. PMID- 4291631 TI - Potentiation of catecholamines by a new diphenylalkanolamine. II. Potentiation in various isolated organs. PMID- 4291632 TI - Salt-induced alteration of D(-) lactate dehydrogenase from Polyspondylium pallidum. PMID- 4291633 TI - Clinical trials with N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide hydrochloride in malignant lymphoma and other disseminated neoplasia. PMID- 4291634 TI - Variations in survival among patients with carcinoma of the ovary. Analysis of 253 cases according to histologic type, anatomical stage and method of treatment. PMID- 4291635 TI - Value of desoxyribonucleic acid (DNA) in evolution of carcinomas of the human breast. PMID- 4291636 TI - Occurrence of tumors in dysgenetic gonads. PMID- 4291639 TI - Immunological analysis of extracts from livers in the course of carcinogenesis. PMID- 4291638 TI - [Adrenal cortex function test using synthetic 24-amino-acid ACTH--rapid ACTH test]. PMID- 4291640 TI - Toxohormone studies in autochthonous tumor-host system. PMID- 4291641 TI - [Polymyxin salt of phenoxymethylpenicillin]. PMID- 4291642 TI - [A study of the action of interferon on poliomyelitis virus in mouse embryo tissue cultures]. PMID- 4291643 TI - [The action of antibiotics on the electrokinetic properties of blood serum proteins]. PMID- 4291644 TI - [Rosenthal fibers and spongioblasts in the central nervous system. I. Occurrence in distal ventricular reparative gliosis; demonstration of fibers in the cellular picture]. PMID- 4291646 TI - Succinate-dehydrogenating activity and cytochromes of hepatic microsomes. PMID- 4291645 TI - Anion and substrate inhibition and kinetic behavior of NAD+-specific isocitrate dehydrogenase from baker's yeast. PMID- 4291647 TI - Analysis of the conditions causing the oscillatory oxidation of reduced nicotinamide-adenine dinucleotide by horseradish peroxidase. PMID- 4291648 TI - The hydrolysis of inositol phosphates by Aerobacter aerogenes. PMID- 4291649 TI - The influence of age, sex and genetic factors on the mechanical and physico chemical structural stability of collagen fibres in mice. PMID- 4291650 TI - Comparative studies of age tests on collagen fibres. PMID- 4291651 TI - [Local treatment with polymyxin B for Pseudomonas aeruginosa infections in surgical field]. PMID- 4291652 TI - Comparison of ability of defective foreign genomes (PARA and MAC) carried by human adenoviruses to induce SV40 transplantation immunity. PMID- 4291653 TI - Systemic vs. topical conditioning for acute necrosis. PMID- 4291654 TI - [On the varicella virus pneumopathy]. PMID- 4291655 TI - [Secondary cylindroma of the liver]. PMID- 4291656 TI - Bacterial carotenoids XX. The carotenoids of Mycobacterium phlei strain Vera. 2. The structures of the phlei-xanthophylls--two novel tertiary glucosides. PMID- 4291657 TI - Alcohol:NAD oxidoreductase from peas (Pisum sativum). PMID- 4291658 TI - Isolation, structure and synthesis of alkaloids from Valeriana officinalis L. PMID- 4291659 TI - Rous rat sarcoma studied with ferritin-conjugated antibodies. PMID- 4291660 TI - Body temperature, antibody formation and inflammatory response. PMID- 4291661 TI - [Apropos of various elements of the biological status in poisoning by Amanita phalloides]. PMID- 4291662 TI - [A simple apparatus for the determination of various gaseous or volatile poisons]. PMID- 4291663 TI - [Use of beta-propiolactone as an inactivating agent for the preparation of vaccines against aphthous fever]. PMID- 4291664 TI - Effectiveness of Rhizobium as modified by mutation for resistance to antibiotics. PMID- 4291665 TI - Failure to detect interfering agents in febrile respiratory illnesses. PMID- 4291666 TI - Isolation and properties of mutants of Aerobacter aerogenes blocked in nitrate assimilation. PMID- 4291667 TI - Inhibition by azasteroids of reduced nicotinamide adenine dinucleotide oxidation with membrane fragments from Bacillus subtilis. PMID- 4291668 TI - Effect of plaque assay diluent upon enumeration of poliovirus type 1. PMID- 4291670 TI - Influence of relative humidity on the survival of some airborne viruses. AB - A system for studying the effects of relative humidity (RH) and temperature on biological aerosols, utilizing a modified toroid for a static aerosol chamber, is described. Studies were conducted at 23 C and at three RH levels (10, 35, and 90%) with four viruses (Newcastle disease virus, infectious bovine rhinotracheitis virus, vesicular stomatitis virus, and Escherichia coli B T3 bacteriophage). Virus loss on aerosol generation was consistently lower at 90% than at 10 or 35% RH. When stored at 23 C, Newcastle disease virus and vesicular stomatitis virus survived best at 10% RH. Infectious bovine rhinotracheitis virus and E. coli B T3 bacteriophage survived storage at 23 C best at 90% RH. PMID- 4291669 TI - Antibiotic activity in the presence of agar. AB - Agar has been shown to interfere with the activity of some antibiotics against Staphylococcus aureus. This interference has been observed as an increase in the minimal inhibitory concentration and in the diameter of the zone of inhibition. Purifying the agar with water extractions substantially reduced this adverse effect. PMID- 4291671 TI - Agar concentration in counting Clostridium colonies. AB - Decreasing the agar concentration of a counting medium from the usual 1.5% resulted in larger colonies with less interference from gas in Clostridium botulinum 115B and C. sporogenes PA 3679. Optimal agar concentration was 0.65% for C. botulinum with 24-hr incubation and 0.50% for C. sporogenes with 48-hr incubation. Lower concentrations yielded growth too diffuse for counting. Motility was considered the explanation for increased colony size in softer agar. The greater the degree of motility, the greater would be the diffusibility expected, and thus the higher the agar concentration required to insure discrete colonies. For quantitating motility, evaluations were made by use of microscopic examination of liquid cultures and rate of diffusion in a semisolid medium. With both criteria, the degree of motility of C. botulinum 115B clearly exceeded that of C. sporogenes PA 3679. Small-colony variants of C. botulinum in 0.65% agar yielded only small colonies on subculture, with a corresponding decrease in degree of motility of the cells by both criteria. Colony size of the nonmotile C. perfringens ATCC 3624 was unaffected by lowered agar concentrations. PMID- 4291672 TI - [Test of adrenal cortex stimulation with beta-1-24 corticotropin (CIBA 30,920-BA) in children]. PMID- 4291673 TI - Angiotensin alteration of sodium fluxes in smooth muscle. PMID- 4291674 TI - Plaque assay of canine contagious hepatitis virus and antiserum. PMID- 4291675 TI - Nuclear spin resonance evidence for complexing of sodium in frog skin. PMID- 4291676 TI - [Transformation of hamster cells by 2 non-defective and defective strains of Rous virus]. PMID- 4291677 TI - African swine fever. 3. The use of the agar double-diffusion precipitation test for the detection of the virus in swine tissue. AB - The agar double-diffusion precipitation test was applied successfully in the demonstration of ASF viral antigen in spleen and liver from swine experimentally infected by the oral route. Positive reactions were obtained with tissues collected as early as 24 hours after the onset of pyrexia and before other clinical manifestation of the disease. Cross-reactions were observed between the various ASF strains used in the study, making the test practical for routine diagnosis in which different strains may be encountered. PMID- 4291678 TI - African swine fever. IV. Demonstration of the viral antigen by means of immunofluorescence. AB - African swine fever immunofluorescent conjugates were prepared in swine and used successfully in the demonstration of viral antigen in frozen tissue sections and in inoculated tissue culture cells. Cross reactivity was observed with the six strains used in the inoculation of swine. The high antibody content of the serum of immune swine did not interfere with demonstration of the antigen in frozen tissue sections of certain of their organs. The localisation and extent of antigen varied with the stage of infection. The virus was demonstrated in spleen and other organs as early as after one day of pyrexia and until after death of the animal. A pool of hog cholera and African swine fever conjugates stained with dyes of different colours was used in the localisation of respective antigens in experimental mixed infection. PMID- 4291679 TI - African swine fever. V. Cultivation of the virus in primary pig kidney cells. AB - Six strains of African swine fever (ASF) virus were propagated in culture of primary pig kidney (PK) cells. The course of virus growth was followed by means of the fluorescent antibody staining technique. All 6 strains multiplied in the cultures, and 5 of these eventually showed cytopathic effects leading to cell death. Three of the strains were tested for pathogenicity in pigs at various passage levels. Each showed evidence of modification in virulence after a relatively few passages in PK cells. In one case modified virus produced resistance to challenge with homologous virulent virus. All strains rendered the PK cultures capable of hemadsorption of pig erythrocytes. PMID- 4291680 TI - African swine fever. II. Detection of the virus in swine tissues by means of the modified direct complement-fixation test. AB - The modified direct complement-fixation test, supplemented with unheated normal calf serum, was used to demonstrate antibodies in sera of swine immunized to African swine fever virus. These antibodies did not react in the ordinary direct non-supplemented complement-fixation test.African swine fever complement-fixing antigen in infected swine tissue is not denatured by extraction with fat solvents. Consequently, good antigens devoid of non-specific reactivity were obtained by extraction with a mixture of acetone and ether. The virus was detected in infected swine tissue harvested one day after beginning of pyrexia. The modified direct complement-fixation test demonstrated cross-reactions between the six strains of virus studied. PMID- 4291681 TI - The effect of artificial insemination with semen contaminated with IBR-IPV virus. PMID- 4291682 TI - [Pituitary-adrenocortical function of women following Gestagen administration]. PMID- 4291683 TI - [Pituitary-adrenal function in diabetes]. PMID- 4291684 TI - [Histological type and prognosis of corpus carcinoma]. PMID- 4291685 TI - [Effective treatment of viral skin diseases with combinations of proteolytic enzymes]. PMID- 4291686 TI - Effect of angiotensin and phenoxybenzamine on release of norepinephrine in vessels during sympathetic nerve stimulation. PMID- 4291687 TI - Pharmacologic aids in adrenal angiography. PMID- 4291688 TI - Isolation of myxovirus parainfluenza 3 from cattle with respiratory diseases. PMID- 4291689 TI - Epizootiologic studies of bovine myxovirus parainfluenza 3. PMID- 4291690 TI - Non-transfer of RNA from parent to progeny of encephalomyocarditis virus. PMID- 4291691 TI - [The regulation of the glomerulus filtrate and arterial blood pressure by the sodium gradients on the macula densa cells. A hypothesis on the stimulation of the renin-angiotensin system. Also a contribution on the genesis of various types of hypertension]. PMID- 4291693 TI - Fluorescence microscopy with the quartz-iodine lamp. PMID- 4291692 TI - [Early sexual riping caused by primary liver carcinoma: "hepatogenital syndrome"]. PMID- 4291694 TI - Removing viruses from water by polyelectrolytes. PMID- 4291695 TI - Evidence for direct physical bonding between the collagen fibres and apatite cystals in bone. PMID- 4291696 TI - Protein synthesis by amoebal ribosomes. PMID- 4291698 TI - Rhinoviruses: a numbering system. PMID- 4291697 TI - Photo-induced benzyl substitution of flavins by phenylacetate: a possible model for flavoprotein catalysis. PMID- 4291699 TI - Viral transformation of monkey kidney cell cultures. PMID- 4291700 TI - Complex formation, isolation and carcinogenicity of polycyclic aromatic hydrocarbons. PMID- 4291701 TI - Controlled investigations in baboons (Papio cynocephalus) on transmission of SV-5 virus by contact. PMID- 4291702 TI - Use of kieselguhr to increase cell production for animal virus investigations. PMID- 4291703 TI - Differential sensibility of normal and tumour cells in two mouse tissues to the toxic activity of cancerogenic substances belonging to various chemical classes. PMID- 4291704 TI - Occurrence and formation of virus particles in leukemic cells of the lah transplantable mouse leukemia. PMID- 4291705 TI - The effect of ACTH on the catalase activity of the adrenal gland in in vivo experiments. Preliminary communication. PMID- 4291706 TI - [On the immunochemical relationships of Bordetella species]. PMID- 4291707 TI - Myoglobin concentration and cytochrome oxidase activity of the cardiac muscle during iron deficiency in rats. PMID- 4291708 TI - The effect of acidosis upon erythrocyte anaerobic glycolysis. PMID- 4291709 TI - Further studies on the effects of social stress on the resistance to infection with Escherichia coli. PMID- 4291710 TI - Studies on myopathy during corticotrophin treatment in multiple sclerosis patients. PMID- 4291711 TI - [On the prognosis of peripheral auxillary nerve paralysis and C-5 segmental lesions]. PMID- 4291712 TI - [On the question of localized and generalized cytomegalic disease and its importance for the formation of abnormalities]. PMID- 4291713 TI - [Effect of angiotensin II on the pressure in the pulmonary circulation]. PMID- 4291714 TI - [Effect of hydrocortisone and ACTH on levels of sodium, potassium and calcium in secretion of the uterine mucosa in the rat]. PMID- 4291715 TI - [A new intratypic serodifferentiation technic for use with strains of poliomyelitis virus, type 3]. PMID- 4291716 TI - [The aphthous fever virus; study of its ribonucleic acid]. PMID- 4291717 TI - [Curve of inactivation of the aphthous virus with beta-propiolactone. Comparison with other inactivation agents]. PMID- 4291718 TI - [Biochemical and immunological research on snake venom. II. Study of the enzymatic and toxic properties of the fractions obtained by filtration of the venom of Naja nigricollis on sephadex]. PMID- 4291719 TI - [Perfusion with angiotensin II. Pressor and hormonal response in normal children]. PMID- 4291720 TI - Pig-bel--epidemic and sporadic necrotizing enteritis in the highlands of New Guinea. PMID- 4291721 TI - [On the question of indolyl-3-acetaldehyde-mutase in microorganisms]. PMID- 4291722 TI - Inhibition of EMC virus reproduction and prevention of cell death by amino acid analogues and puromycin. PMID- 4291723 TI - [The changes in succinate dehydrogenase activity in Detroit-6 (VA) cells as a result of infection with the hepatitis-infectious-virus]. PMID- 4291724 TI - Properties of the immunogenic and sensitizing activities of Bordetella pertussis in mice. II. Enchancement of susceptibility to bacterial endotoxins. PMID- 4291725 TI - Separation of chlorophylls and related plant pigments by two-dimensional thin layer chromatography. PMID- 4291726 TI - The effect of glycerol on the rate of movement of some amino acids on silica gel thin layers. PMID- 4291728 TI - Nucleotide sequences from the low molecular weight ribosomal RNA of Escherichia coli. PMID- 4291727 TI - Chromatographic separation on silica gel glass fiber paper of compounds from yeast labeled by aspartate-14C. PMID- 4291729 TI - The 5'-terminal dinucleotides of the separated strands of T7 bacteriophage deoxyribonucleic acid. PMID- 4291730 TI - Effects of acetylcholine and other medullary secretagogues and antagonists on the membrane potential of adrenal chromaffin cells: an analysis employing techniques of tissue culture. AB - 1. A method has been devised for isolating adrenal chromaffin cells (from gerbils) and maintaining them in vitro. Transmembrane potentials of these cells were recorded with intracellular micro-electrodes.2. Acetylcholine depolarized the chromaffin cells and so did various other substances known to evoke catecholamine secretion: nicotine, pilocarpine, histamine, 5-hydroxytryptamine, angiotensin, and bradykinin.3. The depolarizing effect of acetylcholine was partially antagonized by hexamethonium and was blocked completely by hexamethonium in combination with atropine.4. Hexamethonium alone completely blocked the response to nicotine; and atropine alone abolished the response to pilocarpine. Thus both nicotinic and muscarinic receptors are present in gerbil chromaffin cells.5. The experiments demonstrate that the various secretagogues and antagonists tested act on the plasma membrane of the chromaffin cell and raise the question whether depolarization may be an important event in stimulus secretion coupling. PMID- 4291731 TI - Respiratory enzymes during aestivation of the Indian apple-snail Pila globosa. PMID- 4291732 TI - [On the problems of bacterial infections in premature and newborn infants]. PMID- 4291734 TI - Inhibition of alcohol dehydrogenase by chloroquine. PMID- 4291733 TI - Effect of calcium ions and pentachlorophenol on the respiration of Micrococcus lysodeikticus. PMID- 4291735 TI - Antibody-mediated immunity to transplantable tumors following reovirus oncolysis. PMID- 4291736 TI - Benign tumours of the submandibular gland. PMID- 4291737 TI - [Paraneoplastic Cushing's syndrome in ectopic ACTH formation]. PMID- 4291738 TI - [The problem of interpretation of "atypical" dysglobulinemias. (Apropos of 4 cases treated in a dermatology department)]. PMID- 4291739 TI - [Articular cartilage and arthrosis]. PMID- 4291740 TI - [The hypo-uricemic action of oral benziodarone]. PMID- 4291742 TI - [Douglasectomy in gynecology]. PMID- 4291741 TI - [The treatment of hydropigenous syndromes with ethacrynic acid. (Apropos of 100 cases)]. PMID- 4291743 TI - [Pelvic pains of genital origin. Chronic sclero-inflammatory pelvioperitonitis. Clinical and histopathological study of 25 cases. Apropos of Allen-Masters syndrome]. PMID- 4291744 TI - [Endometrial polyps of the intramural portion of the Fallopian tube. Their relation to sterility and endometriosis]. PMID- 4291745 TI - [Bacteriological study of non-dysplastic lesions of the cervix uteri]. PMID- 4291746 TI - [Uterine diverticulosis--histogenesis]. PMID- 4291747 TI - [Synechia and intracavitary fibrous polyp]. PMID- 4291748 TI - [Treatment of purulent meningitis in children]. PMID- 4291749 TI - [The antibiotic therapy laboratory in purulent meningitis]. PMID- 4291751 TI - [Current data in psychosomatic medicine]. PMID- 4291750 TI - [Explorations and neurosurgical treatment in meningitis in children and infants]. PMID- 4291752 TI - [Clinical and biological study of a new diuretic (furosemide) in simple obesity]. PMID- 4291753 TI - [Physiology of pigmentary biliary secretion and physiopathology of icterus]. PMID- 4291754 TI - [Discussion on the treatment of information in cardiology. II]. PMID- 4291755 TI - [Sodium bicarbonate water and biliary and external pancreatic secretions]. PMID- 4291756 TI - [Acute respiratory diseases caused by ECHO virus. Clinical observations and virological study]. PMID- 4291757 TI - [A further case of tumor of the olfactory placode]. PMID- 4291758 TI - [Results of the use of synthetic antimalarials in the treatment of scleroses following radiotherapy]. PMID- 4291759 TI - Salmonellosis: the present position in man and animals. Laboratory aspects with particular reference to chemotherapy and control. PMID- 4291761 TI - Properties of cyclic 3',5'-nucleotide phosphodiesterase from rat brain. PMID- 4291760 TI - Studies on phosphate binding sites of inosinic acid dehydrogenase and adenylosuccinate synthetase. PMID- 4291762 TI - The effect of rotenone on beef liver glutamic dehydrogenase. PMID- 4291763 TI - Chemistry, microscopy, and performance of methylated glycerol-treated muscle fibers. PMID- 4291764 TI - Ultraviolet, visible, circular dichroism, and electron paramagnetic resonance spectra of the copper (II) complexes of thyroxine and thyroxine analogs. PMID- 4291765 TI - [Diagnosis and therapy of craniospinal tumors]. PMID- 4291766 TI - Detection of clostridial hemolysin formed in vivo. AB - Experimental clostridial myonecrosis closely resembling gas gangrene was produced in goats by the intramuscular injection of washed clostridia suspended in adrenalin. The preparation provides a model for the study of clostridial myonecrosis that is relatively isolated from preceding trauma. A new test for the demonstration of clostridial exotoxins, the hemolysin indicator plate test, was described. This test gave reliable results within 6 hr, and only minute quantities of test material were required. Application of this test to would exudates of goats with experimental clostridial myonecrosis demonstrated the presence of the gamma toxin of Clostridium novyi, alpha toxin of C. septicum, and the alpha toxin of C. perfringens in exudates from animals injected with washed Clostridium bacilli suspended in adrenalin. Exudates from goats injected with C. perfringens were lethal for mice and produced necrosis of guinea pig skin typical of C. perfringens. The convincing demonstration of clostridial exotoxins formed in vivo in this experimental model could be the basis for definition of clostridial exotoxin actions which have evaded study in the past. PMID- 4291767 TI - Characterizion of Mycoplasma pulmonis variants isolated from rabbits. II. Basis for differentiation of antigenic subtypes. AB - The antigen composition of Mycoplasma pulmonis variants was studied by complement fixation, agar-gel diffusion, and growth-inhibition tests. Two classes of complement-fixing antigens were demonstrated for M. pulmonis strains 47 and 63: (i) cross-related, heat-labile, water-soluble antigens, and (ii) high-titered, subtype-specific, heat-stable, water-soluble antigens. Lipid antigens prepared by organic solvent fractionation were low-titered antigens and showed little specificity. With the aid of agar-gel double-diffusion plates, the subtype specific antigens were found to be precipitated by trichloroacetic acid and to be stable to periodate, but they were inactivated by pronase. Pronase-stable, periodate-labile precipitating antigens were observed as common components between the two variants. Antisera prepared with boiled antigens were found to be serologically active on gel diffusion but lacked neutralizing ability in growth inhibition tests. Each of three strains of M. pulmonis (47, 63, ATCC 14267) could be identified as a variant because each strain possessed immunologically distinct heat-stable subtype-specific antigen(s). PMID- 4291768 TI - Local and regional applications of hydrogen peroxide in the control of clostridial myositis in rabbits. AB - The intra-arterial infusion of hydrogen peroxide has been used as a method for producing a hyperoxic environment in experimental animals for the treatment of experimentally induced clostridial myositis. Eighty-five rabbits were employed in this study; 43 were controls and 42 were experimental animals. In the experimental study, 21 animals were treated with hydrogen peroxide by each route of administration. In this group, 52.4% of the animals receiving the intra arterial infusion and 66.6% receiving intramuscular clysis survived. There were no survivors past 72 hr in the control group. PMID- 4291769 TI - Prevention by polymyxin B of endotoxin lethality in mice. PMID- 4291770 TI - The effect of hyperbaric oxygenation on the uptake of radioisotopes by tumors in rats. PMID- 4291771 TI - Evaluation of ethiodol for lung scanning. PMID- 4291772 TI - The uptake of technetium-99m pertechnetate by the choroid plexus. PMID- 4291773 TI - Estrogen effects on human oral epithelium. Cytologic, histologic and clinical comparisons. PMID- 4291774 TI - The nucleolus, virus infection, and trisomy in man. PMID- 4291775 TI - Is there proton noise in mitochondrial membranes leading to chance fluctuations in pH? PMID- 4291776 TI - Demonstration of IgA polioantibody in saliva, duodenal fluid and urine. PMID- 4291777 TI - Time-dependence and count-dependence in microbial infection. PMID- 4291778 TI - Pitfalls in electron spin resonance spectrometry in biological tissues. PMID- 4291779 TI - Activity of a macrophage factor in collagen formation by silica. PMID- 4291780 TI - Haemolytic activity of asbestos and other mineral dusts. PMID- 4291781 TI - Synergistic toxicity and carcinogenicity of 'freons' and piperonyl butoxide. PMID- 4291782 TI - Comparison of techniques for obtaining single cell suspensions from tumors. PMID- 4291783 TI - Presence of antibodies against parainfluenza 3 virus in camel and sheep sera. PMID- 4291784 TI - The mineral content of bituminous coal miners' lungs. PMID- 4291785 TI - Hydrolysis of pregnanediol glucuronide by sodium periodate. PMID- 4291786 TI - The activities of fructose 1,6-diphosphatase, phosphofructokinase and phosphoenolpyruvate carboxykinase in white muscle and red muscle. AB - 1. The activities of fructose 1,6-diphosphatase were measured in extracts of muscles of various physiological function, and compared with the activities of other enzymes including phosphofructokinase, phosphoenolpyruvate carboxykinase and the lactate-dehydrogenase isoenzymes. 2. The activity of phosphofructokinase greatly exceeded that of fructose diphosphatase in all muscles tested, and it is concluded that fructose diphosphatase could not play any significant role in the regulation of fructose 6-phosphate phosphorylation in muscle. 3. Fructose diphosphatase activity was highest in white muscle and low in red muscle. No activity was detected in heart or a deep-red skeletal muscle, rabbit semitendinosus. 4. The lactate-dehydrogenase isoenzyme ratio (activities at high and low substrate concentration) was measured in various muscles because a low ratio is characteristic of muscles that are more dependent on glycolysis for their energy production. As the ratio decreased the activity of fructose diphosphatase increased, which suggests that highest fructose-diphosphatase activity is found in muscles that depend most on glycolysis. 5. There was a good correlation between the activities of fructose diphosphatase and phosphoenolpyruvate carboxykinase in white muscle, where the activities of these enzymes were similar to those of liver and kidney cortex. However, the activities of pyruvate carboxylase and glucose 6-phosphatase were very low in white muscle, thereby excluding the possibility of gluconeogenesis from pyruvate and lactate. 6. It is suggested that the presence of fructose diphosphatase and phosphoenolpyruvate carboxykinase in white muscle may be related to operation of the alpha-glycerophosphate-dihydroxyacetone phosphate and malate-oxaloacetate cycles in this tissue. PMID- 4291788 TI - The enzymic hydrolysis of amygdalin. AB - Chromatographic examination has shown that the enzymic hydrolysis of amygdalin by an almond beta-glucosidase preparation proceeds consecutively: amygdalin was hydrolysed to prunasin and glucose; prunasin to mandelonitrile and glucose; mandelonitrile to benzaldehyde and hydrocyanic acid. Gentiobiose was not formed during the enzymic hydrolysis. The kinetics of the production of mandelonitrile and hydrocyanic acid from amygdalin by the action of the beta-glucosidase preparation favour the probability that three different enzymes are involved, each specific for one hydrolytic stage, namely, amygdalin lyase, prunasin lyase and hydroxynitrile lyase. Cellulose acetate electrophoresis of the enzyme preparation showed that it contained a number of enzymically active components. PMID- 4291789 TI - The effect on some enzymes of rat tissue of diets low in fat content. AB - 1. Rats of two strains were kept on three different diets; one was a commercial diet of rat pellets, one contained about 80% of sucrose and 20% of casein and was supplemented with corn oil, and the third was a similar diet without the corn oil. 2. On the commercial diet, the specific activities of pyruvate kinase, glucose 6-phosphate dehydrogenase and fructose 1,6-diphosphatase in the livers of one strain of rats (strain A) were 1.5-3 times those in the other strain (strain B). When the diet high in sucrose and supplemented with corn oil was given, there were large increases in the specific activity of pyruvate kinase, glucose 6 phosphate dehydrogenase and fructose 1,6-diphosphatase in the livers of strain A rats. With strain B rats the increases were much smaller. Omission of corn oil from the diet caused a threefold increase in the specific activity of glucose 6 phosphate dehydrogenase in strain B rats, but had little effect on other enzymes. 3. The enzymes of the kidneys and hearts of strain A rats were also more active than those of strain B rats. In strain A rats, the specific activities of pyruvate kinase and fructose 1,6-diphosphatase in the kidney increased when the sucrose content of the diet was high, but in the kidneys of strain B rats there was little change. 4. In strain A rats, the specific activity of pyruvate kinase in the heart more than doubled with the high-sucrose-corn oil diet and increased threefold when corn oil was omitted. No changes were seen in strain B rats. 5. In strain A rats, omission of corn oil from the diet increased the ability of the kidneys to synthesize glucose from lactate. 6. In strain B rats, addition of corn oil to the diet resulted in a decrease in the liver in the specific activity of ATP citrate lyase and in the ability to incorporate acetate into lipid. PMID- 4291787 TI - The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. AB - 1. The concentrations of the oxidized and reduced substrates of the lactate-, beta-hydroxybutyrate- and glutamate-dehydrogenase systems were measured in rat livers freeze-clamped as soon as possible after death. The substrates of these dehydrogenases are likely to be in equilibrium with free NAD(+) and NADH, and the ratio of the free dinucleotides can be calculated from the measured concentrations of the substrates and the equilibrium constants (Holzer, Schultz & Lynen, 1956; Bucher & Klingenberg, 1958). The lactate-dehydrogenase system reflects the [NAD(+)]/[NADH] ratio in the cytoplasm, the beta-hydroxybutyrate dehydrogenase that in the mitochondrial cristae and the glutamate dehydrogenase that in the mitochondrial matrix. 2. The equilibrium constants of lactate dehydrogenase (EC 1.1.1.27), beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) and malate dehydrogenase (EC 1.1.1.37) were redetermined for near-physiological conditions (38 degrees ; I0.25). 3. The mean [NAD(+)]/[NADH] ratio of rat-liver cytoplasm was calculated as 725 (pH7.0) in well-fed rats, 528 in starved rats and 208 in alloxan-diabetic rats. 4. The [NAD(+)]/[NADH] ratio for the mitochondrial matrix and cristae gave virtually identical values in the same metabolic state. This indicates that beta-hydroxybutyrate dehydrogenase and glutamate dehydrogenase share a common pool of dinucleotide. 5. The mean [NAD(+)]/[NADH] ratio within the liver mitochondria of well-fed rats was about 8. It fell to about 5 in starvation and rose to about 10 in alloxan-diabetes. 6. The [NAD(+)]/[NADH] ratios of cytoplasm and mitochondria are thus greatly different and do not necessarily move in parallel when the metabolic state of the liver changes. 7. The ratios found for the free dinucleotides differ greatly from those recorded for the total dinucleotides because much more NADH than NAD(+) is protein-bound. 8. The bearing of these findings on various problems, including the following, is discussed: the number of NAD(+)-NADH pools in liver cells; the applicability of the method to tissues other than liver; the transhydrogenase activity of glutamate dehydrogenase; the physiological significance of the difference of the redox states of mitochondria and cytoplasm; aspects of the regulation of the redox state of cell compartments; the steady-state concentration of mitochondrial oxaloacetate; the relations between the redox state of cell compartments and ketosis. PMID- 4291790 TI - [Mixed tumor of the salivary gland]. PMID- 4291791 TI - In vitro effects of fluoride on tricarboxylic acid cycle dehydrogenases and oxidative phosphorylation. I. PMID- 4291792 TI - Reflex control of blood pressure by the right subclavian baroreceptor in experimental renal hypertension of rabbit. PMID- 4291793 TI - The effects of angiotensin II on the 45-Ca distribution of the rat. PMID- 4291794 TI - The pathology of gastric carcinoma. PMID- 4291795 TI - Primary neoplasms of the alimentary canal in whites and Bantu of the Transvaal, 1949-1953. A histopathological series. PMID- 4291796 TI - [Changes in plasmatic renin levels and sensitivity to the pressor action of angiotensin in dogs with hypertension induced by defrenation or by renal artery stenosis]. PMID- 4291797 TI - [Routine chromatographic determination of urinary pregnandiol and pregnanetriol on micro-columns of silica gel]. PMID- 4291798 TI - Clostridium perfringens food poisoning. PMID- 4291799 TI - Correlation of structure and function in selected tumors of the human nervous system. PMID- 4291800 TI - Experiences in pancreas scanning using 75-Se-selenomethionine. PMID- 4291801 TI - [Histoenzymological maturation of the white substance and vascular walls of the brain in children]. PMID- 4291802 TI - Effects of glucose feeding, cortisol, and insulin on liver glycogen synthesis in the rat. PMID- 4291803 TI - Quantitative study of the diabetogenic action of ACTH and growth hormone in partially pancreatectomized rats. PMID- 4291804 TI - ACTH-mediated insulin secretion: effect of aminophylline. PMID- 4291805 TI - Density gradient centrifugation of human and bovine parathyroid hormone. PMID- 4291806 TI - Thyrocalcitonin activity in hypercalcemia produced by calcium salts, parathyroid hormone and vitamin D. PMID- 4291809 TI - Aging at the cellular level. PMID- 4291807 TI - Renin-angiotensin system, adrenal steroids and sodium depletion in a primitive mammal, the American opossum. PMID- 4291808 TI - Mechanism of the inhibitory effect of iodide on thyroidal 131-I release in the rat. PMID- 4291810 TI - Reconstruction of hand surface defects. PMID- 4291811 TI - Safety factors in dacryocystorhinostomy. PMID- 4291812 TI - An arrhenoblastoma with estimations of androgenic steroids. PMID- 4291813 TI - The value of treatment of cerebral tumours. PMID- 4291814 TI - Electron spin resonance spectra of heated polynuclear hydrocarbons. PMID- 4291815 TI - Aminoacyltransferase stimulation of protein synthesis by pig adrenal polysomes. PMID- 4291816 TI - Isolation from Bordetella pertussis of protective antigen free from toxic activity and histamine sensitizing factor. PMID- 4291817 TI - Inhibition of placental steroid synthesis by steroid metabolites: possible feedback control. PMID- 4291818 TI - Bronchiolar carcinoma: a case report with pulmonary function studies. PMID- 4291819 TI - The young pig. Alimentary disorders. PMID- 4291820 TI - Gynecologic cancer. Vaginal cytology of female children. PMID- 4291821 TI - Ovarian malignancy in children, with special reference to the germ-cell tumors. PMID- 4291822 TI - Radiation therapy in the management of children with gynecologic cancers. PMID- 4291823 TI - True precocious puberty. PMID- 4291824 TI - Adrenal virilism in childhood. PMID- 4291825 TI - Decomposition of polyphosphate in yeast cell by freeze-thawing. PMID- 4291826 TI - Location of polyphosphate and polyphosphatase in yeast cells and damage to the protoplasmic membrane of the cell by freeze-thawing. PMID- 4291827 TI - Enzymic formation of D-kynurenine from D-tryptophan. PMID- 4291828 TI - The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast. PMID- 4291829 TI - Some properties of variously activated microsomal glucose-6-phosphatase, inorganic pyrophosphatase and inorganic pyrophosphate-glucose phosphotransferase. Shift in pH optimum. PMID- 4291830 TI - Nature of enzyme-coenzyme interactions in liver alcohol dehydrogenase. PMID- 4291832 TI - Comparative effects, in vitro, of various detergents on liver glucose-6-phosphate phosphohydrolase, inorganic pyrophosphate-glucose phosphotransferase, and acid inorganic pyrophosphatase activities. PMID- 4291831 TI - Benzylalcohol dehydrogenase, a new alcohol dehydrogenase from Pseudomonas sp. PMID- 4291833 TI - Some chemical and physical properties of thermostable glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus. PMID- 4291834 TI - ATP-dependent reduction of azide and HCN by N2-fixing enzymes of Azotobacter vinelandii and Clostridium pasteurianum. PMID- 4291835 TI - Effect of magnesium ions on coenzyme A and pyrophosphate derivatives inhibition of yeast glucose-6-phosphate dehydrogenase. PMID- 4291836 TI - Hormonal effects on the development of glutamine synthetase in the embryonic chick retina. PMID- 4291837 TI - Effects of epinephrine, corticotropin, and thyrotropin on lipolysis and glucose oxidation in rat adipose tissue. AB - (Log dose)-response curves have been determined for lipolysis and for the conversion of glucose-(14)C to (14)CO(2) by adipose tissue from rats in the presence of epinephrine, corticotropin, and thyrotropin. The stimulatory effect of epinephrine on lipolysis was greater than that of corticotropin or thyrotropin. Lipolysis induced by epinephrine was inhibited by propranolol but only slightly by phenoxybenzamine, whereas lipolysis induced by corticotropin was inhibited by phenoxybenzamine to a much greater extent than by propranolol. Neither blocking drug had a pronounced effect on the response to thyrotropin. Epinephrine stimulated the oxidation of glucose-(14)C to CO(2) more than did either thyrotropin or corticotropin. Moreover, epinephrine stimulated the conversion of glucose-(14)C to CO(2) and fatty acids even when lipolysis was not increased. These studies indicate that epinephrine can affect glucose utilization independently of its effect on lipolysis. PMID- 4291838 TI - Efficient elution of rabbit liver and plasma phospholipids from thin-layer plates. AB - The efficient recovery (96.3-99.6%) of phospholipids by elution from thin-layer plates is documented. The composition of phospholipids from rabbit liver and plasma is reported. PMID- 4291839 TI - Numerical classification of some viruses, bacteria and animals according to nearest-neighbour base sequence frequency. PMID- 4291840 TI - Effect of stimulus intensity on the rising phase of the nerve action potential in healthy subjects and in patients with peripheral nerve lesions. PMID- 4291842 TI - Thermal analysis and stability of refractory investments. PMID- 4291841 TI - Acute necrotizing encephalitis: a problem in diagnosis. PMID- 4291843 TI - Stevens-Johnson syndrome associated with Mycoplasma pneumoniae infection. PMID- 4291844 TI - Acetylcholine depolarization of bullfrog sympathetic preganglionic nerve terminals. PMID- 4291845 TI - [On the symptomatology, diagnosis and therapy of corpora quadrigeminal tumors]. PMID- 4291846 TI - Rehabilitative digital surgery in epidermolysis bullosa. PMID- 4291847 TI - Breast reconstruction following radical mastectomy. PMID- 4291848 TI - Radiography of the acute abdomen. PMID- 4291849 TI - Myxovirus parainfluenza-3 respiratory infection in dairy cattle. PMID- 4291850 TI - Viral respiratory infection in commercial feedlot cattle. PMID- 4291851 TI - Antibody response to inactivated preparations of African swine fever virus in pigs. PMID- 4291852 TI - Porcine enteroviruses: a serologic comparison of thirty-eight Pennsylvania isolates with other reported North American strains, Teschen, Talfan, and T80 serums--a progress report. PMID- 4291853 TI - Metabolism of myo-inositol in animals. II. Complete catabolism of myo-inositol 14C by rat kidney slices. PMID- 4291854 TI - Intracellular distribution of 5'-ribonuclease and 5'-phosphodiesterase in rat liver. PMID- 4291856 TI - Mammalian lipoic acid activating enzyme. PMID- 4291855 TI - The isolation, composition and physicochemical properties of deoxyribonucleic acid from Bordetella pertussis. PMID- 4291857 TI - Stereospecificity of the allosteric NADH dehydrogenase from Mycobacterium tuberculosis. PMID- 4291858 TI - [Histochemistry of lipids of the suprarenal cortex in radiation injury of the organism]. PMID- 4291859 TI - Evidence for the binding of oxygen and carbon monoxide by succinic dehydrogenase. PMID- 4291860 TI - The inhibition of cytochrome oxidase activity by cytochrome c peptide fragments. PMID- 4291861 TI - Biosynthesis of aminoacyl derivatives of phosphatidylglycerol. PMID- 4291863 TI - The properties of non-virus-producing (NP) Rous sarcoma cells. PMID- 4291862 TI - The intracellular distribution of [1-3H]cholecalciferol in the intestine of vitamin D-deficient and -supplemented rats. AB - 1. [1-(3)H]Cholecalciferol was administered orally at two dosages to vitamin D deficient and -supplemented rats, and the intracellular distribution of the vitamin in the intestinal mucosa studied. 2. The concentration of cholecalciferol was highest in a fraction consisting of brush borders and nuclei. The microsomal fraction contained a higher concentration of the vitamin than the mitochondrial fraction in deficient rats, irrespective of the dose, whereas in the vitamin D supplemented rats the concentration was the same in the two fractions. 3. Appreciable metabolism of the cholecalciferol occurred only in the supplemented rats and the metabolites were found predominantly in the mitochondrial fraction. 4. The cholecalciferol is more tightly bound to the microsomal fraction than to the mitochondrial fraction. 5. Experiments conducted in vitro have shown that all the intracellular particles combine with the vitamin either when dissolved in ethanol or bound to albumin. However, such an uptake does not account for the high concentration of radioactivity found in vivo in the fraction containing nuclei and brush border, nor for the tightly bound vitamin in the microsomal fraction. PMID- 4291864 TI - Synthesis of an antigenic copolymer of angiotensin and succinylated poly-L lysine. PMID- 4291865 TI - Influence of thymectomy on plasma corticosterone in the rat. PMID- 4291866 TI - Pseudocowpox in dairy cattle. PMID- 4291868 TI - Growth of the L-cell in galactose medium. PMID- 4291867 TI - Biochemical and physicochemical characterization of collagen-synthesizing polyribosomes. AB - Synthesis of collagen on polyribosomes has been demonstrated in vitro in chick embryo corium by radioisotope incorporation, zone centrifugation through sucrose gradients, and analytical ultracentrifugation. Collagen synthesis was associated with polyribosomes ranging in size, as reflected by their sedimentation constants, from about 180S to approximately 1600S. Most of the newly formed collagen, hydroxyproline, was present on the largest polyribosome aggregates ( approximately 350-1600S), but small polyribosomes ( approximately 180-200S) also contained collagen. On the basis of the proline-(14)C/hydroxyproline-(14)C ratios and the disrupting effect of collagenase, the proposal is made that the 350-1600S polyribosomes from this tissue are involved predominantly in collagen synthesis. The large polyribosomes are disrupted extensively by collagenase but only partially by ribonuclease and trypsin. Therefore, it appears that they are stabilized by the interaction of newly forming collagen chains. Evidence is presented consistent with the hypothesis that these large polyribosomes are formed by the aggregation of small polyribosomes (180-200S) through the interaction of collagen polypeptides. It is suggested that these small polyribosomes might be involved in the synthesis of subunits of the collagen alpha chain. PMID- 4291869 TI - The growth of Mycoplasma bovigenitalium in cell cultures. PMID- 4291871 TI - Supercoiling of polyoma virus DNA measured by its interaction with ethidium bromide. PMID- 4291870 TI - Synthesis of some orotic acid analogs as potential antimetabolites. PMID- 4291872 TI - Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors. PMID- 4291873 TI - Selective dissociation of histones from calf thymus nucleoprotein. PMID- 4291875 TI - Isolation of sendai virus as a latent respiratory virus in mice. PMID- 4291874 TI - An electron microscopic study of hypertrophic neuropathy of Dejerine and Sottas. PMID- 4291876 TI - Control of Pseudomonas aeruginosa in an experimental mouse colony. PMID- 4291877 TI - A comparison of vitamin D2 and D3 in New World primates. I. Production and regression of osteodystrophia fibrosa. PMID- 4291878 TI - The effect of phospholipase C on influenza viruses: limited release of "soluble" V-antigens and of neuraminidase. PMID- 4291879 TI - Some evidence for differentiation of ACTH and norepinephrine lipolytic receptors in adipose cells. PMID- 4291880 TI - Mutants of the simian virus 40 which differ in cell-transforming activity. PMID- 4291881 TI - Activity of thymidine kinase in mouse embryo cells infected with polyoma virus. PMID- 4291882 TI - Purification of human angiotensin. PMID- 4291883 TI - Isolation of a non-dialysable active pressor principle from pig serum. PMID- 4291884 TI - Differences in uridine diphosphate galactose-4-epimerase between haemolysates of newborns and of adults. PMID- 4291885 TI - Increased incidence of avian leukosis in response to excess vitamin A. PMID- 4291886 TI - Antigen deletions in carcinogen-induced rat hepatomata. PMID- 4291887 TI - Induction of hepatoma in mice by carcinogens of the polycyclic hydrocarbon type. PMID- 4291888 TI - Pathogenicity of the chicken sarcoma virus (Schmidt-Ruppin) for amphibians and reptiles. PMID- 4291889 TI - Hypertrophic neuropathy. PMID- 4291890 TI - [Autonomous hepatic tuberculosis. (Apropos of 3 cases)]. PMID- 4291891 TI - [Plasmacytic leukemia. Apropos of 3 cases]. PMID- 4291892 TI - [Proof of phagocytosis of India ink "in vitro". Its importance in the diagnosis of monocytic leukoses]. PMID- 4291893 TI - [Reticulosarcoma of the small intestine. Clinical and radiological study, lymphography and selective arteriography]. PMID- 4291894 TI - [Association of a bronchial cancer and cancer of the buccal floor]. PMID- 4291895 TI - [Some details on the "x" systolic depression of the jugular venous pulse]. PMID- 4291896 TI - [The ventricular electrical complex with prolonged slow phase]. PMID- 4291897 TI - [Hiatal hernia during respiratory diseases (and especially during pulmonary tuberculosis)]. PMID- 4291898 TI - [Corneal abscesses due to Pseudomonas]. PMID- 4291899 TI - Streptomycin biosynthesis: participation of a phosphatase, aminating enzyme, and kinase in cell-free synthesis of streptidine-P from inosamine-P. PMID- 4291900 TI - Resolution of complex I (DPNH-coenzyme Q reductase) of the mitochondrial electron transfer system. PMID- 4291901 TI - On the submitochondrial localization of l-kynurenine-3-hydroxylase. PMID- 4291902 TI - The effects of mepyrapone (SU 4885) and some hypercholesterolaemic drugs on hepatic sterol and fatty acid oxidation. PMID- 4291903 TI - Blood thiamine and nicotinic acid levels in alcoholism and confusional states. PMID- 4291904 TI - [Influence of injection of ACTH on the survival of Gambusia sp. (teleost fish) after removal of the pituitary gland]. PMID- 4291905 TI - Participation of nicotinamide mononucleotide in pyridine nucleotide synthesis in tumor and host liver. PMID- 4291906 TI - Nucleic acid metabolism in intestinal mucosa. V. Heterogeneity of deoxyribonucleic acid isolated from the intestinal mucosa of the rat. PMID- 4291907 TI - The wheat leaf phosphatases. 8. A preparation with phosphotransferase activity. PMID- 4291909 TI - Collagenolytic activity during mammalian wound repair. PMID- 4291908 TI - A rapid method for the isolation of coeruloplasmin. PMID- 4291910 TI - Thyroid activity and endocrine gland weight in fast- and slow-growing chickens. PMID- 4291911 TI - In situ lobular cancer of the breast. PMID- 4291913 TI - Experimental infectious canine hepatitis. IV. Histological and immunofluorescence studies of the kidney. PMID- 4291914 TI - Foot-and-mouth disease in Myocastor coypus. PMID- 4291912 TI - The submitochondrial localization of monoamine oxidase. An enzymatic marker for the outer membrane of rat liver mitochondria. AB - Controlled osmotic lysis (water-washing) of rat liver mitochondria results in a mixed population of small vesicles derived mainly from the outer mitochondrial membrane and of larger bodies containing a few cristae derived from the inner membrane. These elements have been separated on Ficoll and sucrose gradients. The small vesicles were rich in monoamine oxidase, and the large bodies were rich in cytochrome oxidase. Separation of the inner and outer membranes has also been accomplished by treating mitochondria with digitonin in an isotonic medium and fractionating the treated mitochondria by differential centrifugation. Treatment with low digitonin concentrations released monoamine oxidase activity from low speed mitochondrial pellets, and this release of enzymatic activity was correlated with the loss of the outer membrane as seen in the electron microscope. The low speed mitochondrial pellet contained most of the cytochrome oxidase and malate dehydrogenase activities of the intact mitochondria, while the monoamine oxidase activity could be recovered in the form of small vesicles by high speed centrifugation of the low speed supernatant. The results indicate that monoamine oxidase is found only in the outer mitochondrial membrane and that cytochrome oxidase is found only in the inner membrane. Digitonin treatment released more monoamine oxidase than cytochrome oxidase from sonic particles, thus indicating that digitonin preferentially degrades the outer mitochondrial membrane. PMID- 4291915 TI - Oxidative and glycolytic recovery metabolism in muscle. AB - The average degree of reduction of mitochondrial NAD has been measured in the intact toad sartorius by a fluorometric technique. It has been shown that cytoplasmic NADH does not interfere materially with these measurements. The percentage reduction of this respiratory coenzyme has been determined in a number of physiological steady states which are well correlated with fluorometrically determined levels of NADH in suspensions of mitochondria from the hind leg musculature of the toad. In addition, these findings are closely comparable to similar, spectrophotometric measurements on mitochondria from other sources. In the presence of an adequate O(2) level a single twitch produces a decrease in fluorescence from the resting steady state which is followed by a slow return to the base line condition. This cycle indicates the intensity and the time course of the oxidative recovery metabolism. The area under this curve is directly related to the number of twitches up to three or four. Greater activity produces a curtailment of oxidative recovery due to glycolysis. In the presence of iodoacetate the linear relation holds for five to seven twitches. At still higher levels of activity a curtailment of the change in NAD level sets in, probably due to the removal of AMP by catabolic reactions. PMID- 4291918 TI - Automated determination of rat adrenal ascorbic acid in the bioassay of corticotropin. PMID- 4291917 TI - Determination of 3-beta-hydroxysteroid dehydrogenase system in microgram samples of tissue, quantitative histologic distribution of the enzyme in the rat adrenal and effects of adrenocorticotropin. PMID- 4291916 TI - The role of membrane phosphoglycerate kinase in the control of glycolytic rate by active cation transport in human red blood cells. AB - When the internal Na of human red cells is raised, both K influx and lactate production increase and become more sensitive to the inhibitory action of ouabain. This occurs with either glucose or purine nucleoside as substrate. Fresh whole hemolysates enriched with Na and Mg will convert intermediates above the triose phosphate dehydrogenase step to lactate at a rate which is slowed by ouabain. Intermediates beyond the phosphoglycerate kinase step (PGK) are metabolized at a very rapid rate which is not affected by ouabain. No metabolic effects of ouabain were found in ghost-free hemolysates. Hemoglobin-free ghosts were shown to have both triose phosphate dehydrogenase and PGK activity. The rate of this two-enzyme sequence was found to be a function of the ADP concentration, being maximal when ADP > 0.35 mM. Initial addition of ATP to the ghost system rendered the forward rate of the sequence sensitive to the inhibitory action of ouabain. When the sequence was run in reverse, no inhibitory effect of ouabain could be demonstrated. It is concluded that membrane PGK is a point at which the Na-K transport system can influence the metabolic rate and that this action is possibly exerted via a compartmentalized form of ADP which is an immediate substrate for the ghost PGK. PMID- 4291919 TI - Intercellular bridges between mammalian cells in culture. PMID- 4291921 TI - The interaction of the free radical of 5-methylphenazinium methyl sulfate with the light-induced free radical of Rhodospirillum rubrum chromatophores. PMID- 4291920 TI - Prevention of virus-induced neoplasms in mice through passive transfer of immunity by sensitized syngeneic lymphoid cells. PMID- 4291922 TI - Haptoglobin 2-1 Bellevue, a haptoglobin beta-chain mutant. PMID- 4291923 TI - Studies of adenovirus-SV40 hybrid viruses, VI. Differential effects of interferon on SV40 and adenovirus T antigen formation in cells infected with SV40 virus, adenoviruses, and adenovirus-SV40 hybrid viruses. PMID- 4291924 TI - Isolation and properties of the helical nucleocapsid of the parainfluenza virus SV5. PMID- 4291925 TI - The results of treatment in patients with cultures resistant to streptomycin, isoniazid and PAS: a five-year follow-up. PMID- 4291926 TI - A comparison of microsomal (Na+ + K+)-ATPase with K+-acetylphosphatase. PMID- 4291927 TI - Inhibition of mitochondrial malate dehydrogenase by citrate. PMID- 4291928 TI - Allosteric fine control of citrate synthase in Escherichia coli. PMID- 4291929 TI - The hydrolysis of monophosphoinositide by extracts of brain. PMID- 4291930 TI - Kinetics of NADH oxidation by pigeon-heart mitochondria. PMID- 4291931 TI - Specific action of prolactin on plasma sodium levels in hypophysectomized Poecilia latipinna (Teleostei). PMID- 4291932 TI - Interrelations of selected measurements of the face and body in pre-adolescent and adolescent girls. PMID- 4291933 TI - Hypersensitivity to peptide fragments. PMID- 4291934 TI - Selective extraction of polyoma DNA from infected mouse cell cultures. PMID- 4291935 TI - Effect of the components parts of nicotinamide adenine dinucleotide (NAD) as inhibitors of lactic dehydrogenase. PMID- 4291936 TI - Thiosemicarbazones derived from indanedione-1,3. PMID- 4291937 TI - Action of angiotensin II upon renal vascular resistance. PMID- 4291939 TI - Cytomegalovirus infection after renal allotransplantation. PMID- 4291938 TI - Examination of structural effect on thin-layer chromatographic multiple spot formation of sympathomimetic amines in the presence of hydrochloric acid. PMID- 4291940 TI - Epidermodysplasia verruciformis and epidermoid carcinoma. Electron microscopic observations. PMID- 4291941 TI - [On the genesis of peripheral-atrophic paralysis in spinal heredo-ataxia]. PMID- 4291942 TI - [The entrapment neuropathies of the nervus suprascapularis. A clinical therapeutic study]. PMID- 4291943 TI - Virus-like particles in a patient with chronic lymphocytic leukemia. PMID- 4291944 TI - Viral etiology of Dawson's encephalitis. PMID- 4291945 TI - Diphosphopyridine nucleotide: a cofactor for the polynucleotide-joining enzyme from Escherichia coli. PMID- 4291946 TI - Regions containing repeating base-pairs in DNA from some oncogenic and nononcogenic animal viruses. PMID- 4291947 TI - A specific enzyme defect in gout associated with overproduction of uric acid. PMID- 4291948 TI - Characterization of a polyisoprenoid compound functional in O-antigen biosynthesis. PMID- 4291949 TI - Enzymatic joining of DNA strands: a novel reaction of diphosphopyridine nucleotide. PMID- 4291952 TI - An improved ion-exchange procedure for the chromatography of the metabolites of mevalonate. PMID- 4291951 TI - Influence of high renin substrate levels on renin-angiotensin system in pregnancy. PMID- 4291953 TI - A gas-flow system for control of the temperature of an electron paramagnetic resonance sample at temperatures between 80 and 273 degrees Kelvin. PMID- 4291950 TI - Chemotherapy of cerebral gliomas with intra-carotid methotrexate-infusion. PMID- 4291955 TI - Survival of poliovirus in flowing turbid seawater treated with ultraviolet light. AB - The effectiveness of a model ultraviolet (UV) radiation unit for treating flowing turbid seawater contaminated with poliovirus was determined. At a turbidity of 70 ppm, the observed survival ratios ranged from 1.9 x 10(-3) (99.81% reduction) to 1.5 x 10(-4) (99.98% reduction) at flow rates ranging from 25 to 15 liters/min; no virus was recovered at flow rates of 10 and 5 liters/min. At a turbidity of 240 ppm, the observed survival ratios ranged from 3.2 x 10(-2) (96.80% reduction) to 2.1 x 10(-4) (99.98% reduction) at flow rates ranging from 25 to 5 liters/min. As expected, turbidity had an adverse influence on the effectiveness of UV radiation; however, by adjusting the flow rate of the seawater through the treatment unit, adequate disinfection was shown to be predictable. PMID- 4291956 TI - Enumeration of Bacillus cereus in foods. AB - For the enumeration of vegetative cells and spores of Bacillus cereus in foods, a mannitol-egg yolk-phenol red-agar has been developed which exploits the failure of B. cereus to dissimilate mannitol, and the ability of most strains to produce phospholipase C. When a high degree of selectivity was required, polymyxin B sulfate in a concentration of 10 ppm appeared to be the most effective selective additive. Useful characteristics for the identification of presumptive isolates of B. cereus were found to be: morphology, dissimilation of glucose mostly to acetyl methyl carbinol under anaerobic conditions, hydrolysis of starch and gelatin, reduction of nitrate, and growth on 0.25% chloral hydrate agar. PMID- 4291954 TI - Inactivation of adenovirus and simian virus 40 tumorigenicity in hamsters by vaccine processing methods. AB - The effectiveness of the adenovirus vaccine inactivation process in destroying the tumorigenic potential for hamsters of adenoviruses, simian virus 40 (SV-40), and adenovirus-SV-40 hybrids was studied. Baby hamsters injected with untreated virus and with samples subjected to the complete inactivation process and to portions of the process were observed for tumor development for periods in excess of 300 days. Over 20,000 hamsters were injected. From 1 to 7 hr of exposure to formaldehyde at a concentration of 0.031 m at 37 C was sufficient to destroy the tumorigenicity observed in the nontreated preparations. Since the inactivation process included 48 hr of exposure at 37 C to 0.031 m formaldehyde plus treatment with ultraviolet (UV) and with beta-propiolactone (BPL), it was concluded that the process has a large margin of safety. Adenovirus isolates free from tumorigenic potential are difficult, if not impossible, to obtain. Therefore, a proven inactivation process appears to provide the best assurance for obtaining adenovirus vaccines free from such potential. Data presented suggest that the tumorigenic property of the viruses studied might be independent of the infectivity of the preparation. The tumorigenic property was found to be highly susceptible to formaldehyde, but less sensitive to BPL or UV treatment. In contrast, treatment with UV or BPL decreased viral infectivity more readily than tumorigenicity. The three-stage inactivation process (formaldehyde, UV, and BPL) inactivated both tumorigenicity and infectivity. PMID- 4291957 TI - Statolon-induced resistance of mice to mengovirus. AB - Mice receiving statolon intraperitoneally were 1,000 times more resistant to intraperitoneal challenge with mengovirus than were untreated controls. Protection was afforded when statolon was administered 1 day before or 1 day after intraperitoneal inoculation with the virus. No therapeutic effect was observed when treatment with statolon was delayed for 2 days or more after virus infection. Exposure of mice to a simulated space cabin environment did not increase their susceptibility to the lethal effects of mengovirus infection or eliminate the protective effect of statolon. PMID- 4291959 TI - Studies of baker's yeast metabolism. I. Pyridine nucleotide reduction and oxygen utilization during alcohol oxidation. PMID- 4291958 TI - Production of high-titer antibody in serum and ascitic fluid of hamsters for a variety of virus-induced tumor antigens. AB - Methods not involving the use of viable tumors were developed for production of high-titer antibodies. The methods involved use of tumor homogenates. Homogenates from all tumor lines tested contained the characteristic tumor antigen. Attempts to isolate virus failed, and virus antigens could not be demonstrated. Immunization with tumor homogenates, in Freund's complete adjuvant, resulted in high antibody levels. None of the animals so immunized developed tumors. PMID- 4291960 TI - Studies of baker's yeast metabolism. II. The role of adenine nucleotides and inorganic phosphate in the control of respiration during alcohol oxidation. PMID- 4291961 TI - Studies of baker's yeast metabolism. 3. Oxidation of acetaldehyde. PMID- 4291962 TI - Mutants partially deficient in alcohol dehydrogenase in Schizosaccharomyces pombe. PMID- 4291963 TI - Inhibition of malate dehydrogenase by phenols and the influence of ring substituents on their inhibitory effectiveness. PMID- 4291964 TI - The binding of NADH to liver alcohol dehydrogenase: a two step reaction. PMID- 4291965 TI - The effect of the 57-Fe hyperfine interaction on the EPR spectrum of spinach ferredoxin. PMID- 4291966 TI - AMP-sensitive fructose diphosphatase in higher plants: effects of carbon sources on the level of the enzyme. PMID- 4291967 TI - Activator-inhibitor interactions in the adenosine diphosphate glucose pyrophosphorylase of Escherichia coli B. PMID- 4291968 TI - The induction of NAD kinase by DDT in Triatoma infestans. PMID- 4291969 TI - The effects of ions and freeze-thawing on supernatant and mitochondrial malate dehydrogenase. PMID- 4291971 TI - Excretion of phospholipids by men on fat-free diet. PMID- 4291970 TI - Studies on the conformational changes of mitochondrial malate dehydrogenase in urea-phosphate solutions. PMID- 4291972 TI - Excretion of phospholipids by men on high fat diets. PMID- 4291973 TI - Composition of epiphyseal cartilage. V. Amino acid and amino sugar composition of epiphyseal cartilage of rachitic chicks; changes effected by vitamin D-3. PMID- 4291974 TI - Isolation of a series of Mengo virus variants differing in sensitivity to polyanions. PMID- 4291977 TI - Bovine enteric cytopathogenic viruses. IV. Attempts to identify three prototype strains by neutralization tests with bacterial, bovine, and human reference antigens and antisera. PMID- 4291975 TI - The pharmacology of the cardiac muscle of the great veins of the rat. PMID- 4291976 TI - Urinary steroid spectrum by gas chromatography. PMID- 4291978 TI - The effect of polyoma virus on differentiating multinucleated muscle fibers. PMID- 4291979 TI - [Drug shock from the clinical point of view]. PMID- 4291980 TI - Autoimmunity and malignancy in New Zealand black mice. PMID- 4291981 TI - The effect of ACTH on hormone excretion in patients with rheumatoid arthritis. PMID- 4291983 TI - Fish pox in the roach (Rutilus rutilus L.). PMID- 4291982 TI - The measurement of hormones and their metabolites. PMID- 4291984 TI - Psychosomatic approach to bronchial asthma. A study of 50 adult asthmatics. PMID- 4291985 TI - The influence of different levels of serum antibody on the susceptibility of rabbit oral mucosa to experimental herpes simplex virus infection. PMID- 4291986 TI - U.V. stabilization of rescued poliovirus. PMID- 4291987 TI - Isolation of protective antigen from Bordetella pertussis. PMID- 4291989 TI - Clostridium perfringens polynucleotide phosphorylase: two molecular species. PMID- 4291988 TI - Contraction of hypotonically swollen mitochondria by oxidizable substrates. PMID- 4291990 TI - Stepwise degradation of P32-labeled rat liver ribosomal ribonucleic acids with snake venom phosphodiesterase. PMID- 4291991 TI - Inorganic pyrophosphate as an energy donor in photosynthetic and respiratory electron transport phosphorylation systems. PMID- 4291992 TI - The effect of UV-irradiation on the plaque-forming ability of single- and double stranded polyoma virus DNA. PMID- 4291993 TI - The specificities and configurations of ternary complexes of yeast and liver alcohol dehydrogenases. AB - 1. Some aspects of the substrate specificities of liver and yeast alcohol dehydrogenases have been investigated with pentan-3-ol, heptan-4-ol, (+)-butan-2 ol, (+/-)-butan-2-ol, (+/-)-hexan-3-ol and (+/-)-octan-2-ol as potential substrates. The liver enzyme is active with all substrates tested, including both isomers of each optically active alcohol. In contrast, the yeast enzyme is completely inactive towards those secondary alcohols where both alkyl groups are larger than methyl and active with only the (+)-isomers of butan-2-ol and octan-2 ol. 2. The absence of stereospecificity of liver alcohol dehydrogenase towards optically active secondary alcohols and its broad specificity towards secondary alcohols in general are explained in terms of an alkyl-binding site that will react with a variety of alkyl groups and the ability of the enzyme to accommodate a fairly large unbound alkyl group in an active enzyme-NAD(+)-secondary alcohol ternary complex. The absolute optical specificity of the yeast enzyme towards n alkylmethyl carbinols and its unreactivity towards pentan-3-ol, hexan-3-ol and heptan-4-ol are explained by its inability to accept alkyl groups larger than methyl in the unbound position in a viable ternary complex. 3. Comparison of the known configurations of the n-alkylmethyl carbinols and [1-(2)H]ethanol and [1 (3)H]geraniol, which have been used in stereospecificity studies with these enzymes by other workers, provides strong evidence for which alkyl group of the substrate is bound to the enzyme in the oxidation of n-alkylmethyl carbinols. The conclusions reached are, for butan-2-ol oxidation with the liver enzyme, confirmed by deductions from kinetic data obtained with (+)-butan-2-ol and a sample of butan-2-ol containing 66% of (-)-butan-2-ol. 4. Initial-rate parameters for the oxidations of (+)-butan-2-ol, 66% (-)-butan-2-ol and pentan-3-ol by NAD with liver alcohol dehydrogenase are presented. The data are completely consistent with a general mechanism of catalysis previously proposed for this enzyme. PMID- 4291994 TI - IUPAC-IUB Commission on Biochemical Nomenclature. Rules for naming synthetic modifications of natural peptides. Tentative rules. PMID- 4291995 TI - The metabolism of the isomeric tert.-butylcyclohexanones. AB - 1. (+/-)-2-, (+/-)-3- and 4-tert.-Butylcyclohexanone are reduced in the rabbit to secondary alcohols, which are excreted extensively conjugated with glucuronic acid. 2. The major metabolite of (+/-)-2-tert.-butylcyclohexanone is (+)-cis-2 tert.-butylcyclohexanol, which has been isolated from the urine as [(+)-cis-2 tert.-butylcyclohexyl beta-d-glucosid]uronic acid. The minor metabolite is (+) trans-2-tert.-butylcyclohexanol. 3. (+/-)-3-tert.-Butylcyclohexanone is reduced mainly to (+/-)-cis-3-tert.-butylcyclohexanol, and to a smaller extent to (+/-) trans-3-tert.-butylcyclohexanol. 4. 4-tert.-Butylcyclohexanone yields mainly the trans-alcohol, which is excreted in conjugated form and has been recovered from the urine as (trans-4-tert.-butylcyclohexyl beta-d-glucosid)uronic acid. The cis alcohol is formed to a minor extent and excreted in conjugated form. 5. The ratios of the amounts of cis- to trans-alcohols produced by the three ketones differed from the relative amounts of cis- and trans-alcohols produced by the corresponding methylcyclohexanones. 6. From these findings the suggestion is made that two orientations of ketone relative to coenzyme occur: alcohols with an equatorially orientated hydroxyl group are thought to be produced as a result of a ;face-to-face' interaction with NADH, and alcohols with axially orientated hydroxyl groups as a result of a ;perpendicular' interaction. Which will predominate is thought to depend on steric factors, particularly the size and position of alkyl substituents in the substrate. PMID- 4291997 TI - The synthesis of polydeoxyribonucleotide by cell-free extracts of embryonic mouse tissue. AB - The conditions under which soluble extracts prepared from mouse embryos incorporate [(3)H]thymidine 5'-triphosphate into polydeoxyribonucleotide have been studied. In common with similar preparations from other mammalian tissues, mouse-embryo DNA nucleotidyltransferase requires the four complementary deoxyribonucleoside 5'-triphosphates, primer DNA and a bivalent cation for activity. Unlike other mammalian DNA nucleotidyltransferases, the rate and extent of the incorporation of [(3)H]thymidine 5'-triphosphate is much greater with Mn(2+) than with Mg(2+) and, with either Mg(2+) or Mn(2+), maximum activity occurs at pH6.4. The difference between Mg(2+) and Mn(2+) varies markedly with pH, reaching a maximum of six- to eight-fold at pH6.4. PMID- 4291996 TI - Studies on brain-cortex slices. Differences in the oxidation of 14-C-labelled glucose and pyruvate revealed by the action of triethyltin and other toxic agents. AB - 1. The rate of appearance of (14)CO(2) from [6-(14)C]glucose and [3 (14)C]pyruvate was measured. Pyruvate is oxidized to carbon dioxide twice as fast as glucose, although the oxygen uptake is almost the same with each substrate. 2. The presence of 30mum-2,4-dinitrophenol increases the output of (14)CO(2) from [6 (14)C]glucose sixfold whereas the oxygen uptake is not quite doubled. Similar results are obtained with 0.1m-potassium chloride. The stimulating action of these two agents on the output of (14)CO(2) from [3-(14)C]pyruvate is much less than on that from [6-(14)C]glucose. 3. The effects of oligomycin, ouabain and triethyltin on the respiration of control and stimulated brain-cortex slices were studied. Triethyltin (1.3mum) inhibited the oxidation of [6-(14)C]glucose more than 70%, but did not inhibit the oxidation of[3-(14)C]pyruvate. [3 (14)C]pyruvate. 4. The production of lactic acid by brain-cortex slices incubated with glucose is twice as great as that with pyruvate. Lactic acid increases two and a half times in the presence of either triethyltin or oligomycin when the substrate is glucose, but is no different from the control when the substrate is pyruvate. 5. With kidney slices the production of lactic acid from glucose is very low. It is increased by oligomycin but not by triethyltin. 6. The results are discussed in terms of the oxidation of the extramitochondrial NADH(2) produced during glycolysis. PMID- 4291998 TI - Isolation of deoxyribonucleic acid from mammalian tissues. AB - 1. DNA has been isolated from different mammalian tissues. The DNA preparations were free from RNA, protein and polysaccharides and have a similar range of sedimentation coefficients (approx. 24s). 2. Protein was removed by a two-stage extraction with a phenol-cresol mixture by using a detergent with 4 aminosalicylate in the first stage and sodium chloride in the second. 3. Polysaccharides remained in solution when DNA was precipitated with 2 butoxyethanol in the presence of 0.5m-sodium chloride and 1.5m-sodium benzoate. 4. Ribosomal RNA was removed by precipitation in the presence of 3m-sodium chloride at 0 degrees , when DNA remained soluble. PMID- 4291999 TI - A simple procedure for the estimation of very small amounts of nitrogen in lipids. AB - 1. About 0.1mug.atom of combined nitrogen, in lipids and a few other compounds, can be determined quantitatively by the gentle digestion of dry samples in 10ml. test tubes with perchloric acid for 30min., followed by the estimation of the resulting ammonia as the stable blue colour (lambda(max.) 635mmu) produced by the addition of phenol and nitroprusside, an alkaline phosphate buffer and alkaline hypochlorite. 2. Deionized distilled water is required, but the other reagents need no special purification if chosen and handled with care. 3. The results are linear with from 0.015 to 0.15mug.atom of nitrogen, or up to 1mug.atom if the final solutions are diluted with water after full colour development. PMID- 4292000 TI - Control of glycolysis and gluconeogenesis in rat kidney cortex slices. AB - 1. Glucose uptake or glucose formation has been studied in kidney cortex slices to investigate metabolic control of phosphofructokinase and fructose diphosphatase activities. 2. Glucose uptake is increased and glucose formation is decreased by anoxia, cyanide or an uncoupling agent. Under these conditions the intracellular concentrations of glucose 6-phosphate and ATP decreased whereas that of fructose diphosphate either increased or remained constant, and the concentrations of AMP and ADP increased. 3. Glucose uptake was decreased, and glucose formation from glycerol or dihydroxyacetone was increased, by the presence of ketone bodies or fatty acids, or after starvation of the donor animal. Under these conditions, the concentrations of glucose 6-phosphate and citrate were increased, whereas those of fructose diphosphate and the adenine nucleotides were unchanged (see also Newsholme & Underwood, 1966). 4. It is concluded that anoxia and cell poisons increase glucose uptake and decrease gluconeogenesis by stimulating phosphofructokinase and inhibiting fructose diphosphatase, whereas ketone bodies, fatty acids or starvation increase gluconeogenesis and decrease glucose uptake through the citrate inhibition of phosphofructokinase. PMID- 4292001 TI - The stereochemistry of hexahydroprenol, ubiquinone and ergosterol biosynthesis in the mycelium of Aspergillus fumigatus Fresenius. AB - 1. The mycelium of Aspergillus fumigatus has been shown to incorporate mevalonate into squalene, ubiquinone, ergosterol and hexahydroprenol. 2. The (3)H/(14)C ratio in ubiquinone, biosynthesized from [2-(14)C-(4R)-4-(3)H(1)]mevalonate, is the same as in the squalene; essentially no (3)H was incorporated from [2-(14)C (4S)-4-(3)H(1)]mevalonate, indicating the biosynthesis of biogenetically trans isoprene units. 3. The (3)H/(14)C ratio for ergosterol (from ;4R-mevalonate') was 3:5, showing that the proton at C-24 is not lost during alkylation of the side chain; it probably migrates to C-25. 4. As (3)H from both mevalonates was incorporated into the hexahydroprenols the biosynthesis of both cis- and trans isoprene units must occur. 5. The saturated omega- and psi-isoprene units are shown to be biogenetically trans, as are two of the unsaturated residues. 6. The saturated alpha- and unsaturated beta-isoprene residues are both biogenetically cis. 7. An inexplicable loss of approximately half of the olefinic protons from the cis-portion of hexahydroprenol occurs; possible reasons for this loss are discussed. 8. Increase in chain length of the hexahydroprenols is by a cis addition. 9. A biosynthesis of hexahydroprenols by addition of cis-isoprene units to all-trans-geranylgeranyl pyrophosphate, or a dihydro or tetrahydro derivative thereof, is suggested. PMID- 4292003 TI - A note on the effect of different pH values on polyoma virus. PMID- 4292004 TI - Glucose-6-phosphatase assay on microgram amounts of liver tissue. PMID- 4292002 TI - The purification of 3,3-dimethylallyl- and geranyl-transferase and of isopentenyl pyrophosphate isomerase from pig liver. AB - The enzyme catalysing the synthesis of farnesyl pyrophosphate from dimethylallyl pyrophosphate and isopentenyl pyrophosphate, or from geranyl pyrophosphate and isopentenyl pyrophosphate, has been purified 100-fold from homogenates of pig liver. The enzyme has optimum pH 7.9 and requires Mg(2+) as activator in preference to Mn(2+); it is inhibited by iodoacetamide, N-ethylmaleimide, p hydroxymercuribenzoate and phosphate ions in addition to the products of the reaction, inorganic pyrophosphate and farnesyl pyrophosphate. From product inhibition studies of the geranyltransferase reaction, the order of addition of substrates to and release of products from the enzyme has been deduced: geranyl pyrophosphate combines with the enzyme first, followed by isopentenyl pyrophosphate. Farnesyl pyrophosphate dissociates from the enzyme before inorganic pyrophosphate. The existence of isopentenyl pyrophosphate isomerase in liver is confirmed. Methods for the preparation of the pyrophosphate esters of isopentenol, 3,3-dimethylallyl alcohol, geraniol and farnesol are also described. PMID- 4292005 TI - Clinical applicability of urea-LDH test in various pyruvate concentrations. PMID- 4292006 TI - [Study of two female heterozygotes for a partial deletion in one arm of the X chromosome in Mus (Leggada) minutoides musculoides TEMM]. PMID- 4292007 TI - [Virologic study of Berlin sewage in comparison with enteroviruses isolated from clinical material]. PMID- 4292008 TI - [The "carcinomatous and sarcomatous neuritis"]. PMID- 4292009 TI - Myelography in dogs, using water-soluble contrast mediums. PMID- 4292010 TI - Studies on the human oocyte and its follicle. I. Ultrastructural and histochemical observations on the primordial follicle stage. AB - Oocytes in primordial ("resting") follicles in adult human ovaries contain a complex paranuclear structure identified by light microscopists as Balbiani's vitelline body. By electron microscopy this structure is composed of a mass of mitochondria with associated endoplasmic reticulum, multiple compound aggregates which form a ring around the cytocentrum, and a single stack or coil of annulate lamellae either attached to the nuclear membrane or free in the cytoplasm. The compound aggregates contain vacuoles and finely divided electron-opaque material. Evidence is presented for the probable transport of this material between the oocyte and its environment. The cytocentrum contains a central aggregate of amorphous electron-opaque deposits which appear to become periodically aligned on fine fibrils to form the long coarse fibers at the periphery of the cytocentrum. The apparent prevalence of annulate lamellae attached or adjacent to the nuclear membrane of oocytes in ovaries removed during the mid-follicular (estrogenic) phase of the cycle indicates the need for further study of a possible hormonal influence on the resting oocyte. By light microscopy phosphatases were not found within the oocyte, but adenosine-monophosphatase activity is present in the cortical cells surrounding primordial follicles, and also at the periphery of each primitive follicle cell, most prominently at the oocyte side. Glucose-6 phosphate dehydrogenase activity is present within the oocyte cytoplasm. PMID- 4292012 TI - The effects of acetaldehyde on serotonin metabolism. PMID- 4292011 TI - Androgen synthesis in a patient with virilizing adrenocortical carcinoma. PMID- 4292013 TI - Neurologic symptoms in lymphoma. I. Hodgkin's disease. PMID- 4292014 TI - Electronic effects in horse liver alcohol dehydrogenase catalysis. PMID- 4292015 TI - [Electron microscopic observation on virus particles in transplantable mouse sarcoma inoculated with mouse mammary tumor virus]. PMID- 4292017 TI - The role of essential fatty acids in adrenocortical function.A collective review. PMID- 4292018 TI - [Paget's disease of the nipple in a young pregnant woman]. PMID- 4292019 TI - [Fatal experimental tetanus caused by a mixed infection with sublethal doses of perfrigens and tetanus spores]. PMID- 4292020 TI - [Experimental preparation of an antiperfringens hyperimmune serum in sheep]. PMID- 4292021 TI - Action of N'N'-anhydro-bis (beta-hydroxyethyl) biguanide hydrochloride (ABOB) on reproduction of Sendai virus (Myxovirus parainfluenzae 1) in chick embryos. PMID- 4292022 TI - Prednisolone-psychosis. PMID- 4292023 TI - [Determination of renin activity of tissue extracts through incubation with a natural purified substrate]. PMID- 4292024 TI - The effect of conjugated estrogens and estriol succinate on fibrinolysis. A clinical correlation in patients with uterine bleeding. PMID- 4292025 TI - [Hypoglycemic pancreopathy: islet cell hyperplasia, adenoma, carcinoma with hyperinsulinemia]. PMID- 4292026 TI - [Acute renocortical necrosis in the course of corticoid therapy]. PMID- 4292027 TI - [Current status of the treatment of pituitary adenomas]. PMID- 4292028 TI - [Observations on diabetes in cattle due to experimental epizootic aphthae (Preliminary note)]. PMID- 4292029 TI - [Research on the Boehringer-Mannheim biochemical "mono-test", a new modification for the determination, by means of the DPN-dependent reaction, of serum transaminases]. PMID- 4292031 TI - [Corticosteroid therapy of neurologic diseases--with special reference to its adverse effects]. PMID- 4292030 TI - [Action of formaldehyde on the infectious character of MM virus and on its ribonucleic acid]. PMID- 4292033 TI - [Considerations on the main current of neuropathological studies]. PMID- 4292032 TI - [Functional reserves of the adrenal cortex in patients with different disorders of gastric secretion]. PMID- 4292034 TI - [Krukenberg's tumor]. PMID- 4292035 TI - [Results of angiotensin determination in renal hypertension]. PMID- 4292036 TI - [Synthesis of all-D-val-5-angiotensin II-asp-1-beta-amide]. PMID- 4292037 TI - An attempt to treat myocarditis induced in dogs after a modified method of Cavelti. PMID- 4292038 TI - [ESR of the human black hair]. PMID- 4292039 TI - [Effects of adrenal stimulation with corticotropin hormone in rats subjected to whole body radiation with CO 60 gamma rays]. PMID- 4292040 TI - [Current problems of recurrent pneumopathia in young children]. PMID- 4292041 TI - The enzymatic degradation of ultraviolet-irradiated deoxyribonucleic acid. PMID- 4292042 TI - Apparent ESR photosignals in melanin. PMID- 4292043 TI - [Research on the antipolio activity of guanidine: diversity of the antiguanidine effect of amino acids and alkylamines]. PMID- 4292044 TI - [Some properties of an autointerfering virus isolated from gastric contents of patients with epidemic hepatitis]. PMID- 4292045 TI - [Study of inhibitory effects of interferon on ribonucleic acids isolated from poliomyelitis and Scotland encephalitis viruses]. PMID- 4292046 TI - [Production, purification and concentration of bacteriophage D-VII]. PMID- 4292047 TI - [Some properties of various strains of Herpes simplex virus]. PMID- 4292049 TI - Solid benign tumors of the esophagus. PMID- 4292048 TI - [Histochemical investigation of oxidoreductases and esterases in the perikaryon after axotomy]. PMID- 4292050 TI - Nutritional and genetic influences on the dentition of "ia" and "pia" rats. PMID- 4292051 TI - Effect of graded doses of ACTH on parotid fluid corticosteroid levels. PMID- 4292052 TI - Studies of avian sarcoma and erythroblastosis (strain 13). VI. Response in birds to two routes of induction and pathology of a virus-induced tumor. PMID- 4292053 TI - Experimental pox infection in waterfowl. PMID- 4292054 TI - Isolation of a phospholipid renin inhibitor from kidney. PMID- 4292055 TI - Spectroscopic studies on spinach ferredoxin and adrenodoxin. PMID- 4292056 TI - Purification and properties of two acid phosphatase fractions isolated from osmotic shock fluid of Escherichia coli. PMID- 4292057 TI - Glucokinase from Entamoeba histolytica and related organisms. PMID- 4292058 TI - Nucleoside phosphonic acids. II. The synthesis of 5'-deoxythymidine 5'-phosphonic acid and its pyrophosphate derivatives. PMID- 4292059 TI - Action of triton X-100 on ultrastructure and membrane-bound- enzymes of isolated nerve endings from rat brain. PMID- 4292060 TI - Free radicals of biological interest. I. Electron spin resonance spectra of tobacco smoke condensates. PMID- 4292061 TI - Reduced nicotinamide-adenine dinucleotide oxidation in Escherichia coli particles. 3. Cellular location of menadione reductase and ATPase activities. PMID- 4292062 TI - Effects of heparin in vivo on lysosomal enzymes in rat plasma. PMID- 4292063 TI - The incorporation of palmitate-1-14C by rat lung in vitro. PMID- 4292064 TI - Comparative effects of aldosterone and heat acclimatization on oxidative enzymes in rat tissues. PMID- 4292065 TI - Abnormalities of skeletal muscle maturation in brain damaged children: a histochemical study. PMID- 4292066 TI - The simultaneous explantation of the nerve and sarcomatous tissue. PMID- 4292067 TI - Virulence of variola virus isolated from smallpox cases of varying severity. PMID- 4292068 TI - Pituitary hormones and the metabolism of N-hydroxy-N-2-fluorenylacetamide in female rats. PMID- 4292069 TI - The patient with recurrent aphthous ulcers and the patient with recurrent herpes labialis: a study of two population samples. PMID- 4292070 TI - Antigenic identity of interferons induced by different viruses in the same cell system. PMID- 4292071 TI - Adenovirus infection of human embryo liver cells. PMID- 4292072 TI - [2 cases of the Pierre Marie syndrome]. PMID- 4292073 TI - Eosinophilic response in glioblastoma tissue culture after addition of autologous lymphocytes. AB - In experiments designed for the study of interactions in vitro between the cells of glioblastoma multiforme and lymphocytes from the same donor, a marked eosinophilic response was noted in three out of six cases. This was an entirely unexpected finding since few, if any, eosinophils survive in tissue cultures. These cells incorporated (3)H-cytidine and (3)H-leucine 72 hours after the cultures had been established, an indication that they were metabolically active. PMID- 4292074 TI - [Encephalitis of Economo and the arbovirus encephalitides]. PMID- 4292075 TI - [Study of urinary excretion of total 17-hydroxycorticosteroids among children. 3. Variations in urinary excretion of total 17-hydroxycorticosteroids by ACTH and metopirone loading in normal children and those with various diseases]. PMID- 4292076 TI - Effects of renin and ACTH on adrenal steroid secretion in the American bullfrog. PMID- 4292077 TI - Sympathetic and humoral vasoconstrictor responses in deoxycorticosterone hypertension. PMID- 4292078 TI - Interferon production with strain SF-4 of parainfluenza-3 virus. PMID- 4292079 TI - Plaque characteristics of four classes of bovine viruses. PMID- 4292080 TI - Susceptibility of tissue culture cells to foot-and-mouth disease virus: concentration of bovine serum in culture medium. PMID- 4292081 TI - Rates of hydrocortisone and corticosterone secretion in calves. PMID- 4292082 TI - Isolation and characterization of bovine enteric viruses. PMID- 4292083 TI - Portal vein thromboses in malignant hepatoma. PMID- 4292085 TI - Acute necrotizing encephalitis. PMID- 4292084 TI - Impairment of pituitary adrenocorticotrophic function by corticosterone in the blood. PMID- 4292086 TI - Metabolism of aromatic amino acids in collagen diseases: urinary excretion of 3 methoxy-4-hydroxymandelic acid and the interference of 3-methoxy-4 hydroxyphenylpyruvate. PMID- 4292087 TI - Study on glucose-6-phosphatase activity in human serum. PMID- 4292088 TI - Biochemical correlates of respiratory deficiency. 8. A precipitating antiserum against cytochrome oxidase of yeast and its use in the study of respiratory deficiency. PMID- 4292089 TI - Virus study of pock disease among buffaloes. PMID- 4292090 TI - Perforation of peptic ulcer during early management of myocardial infarction. PMID- 4292091 TI - Radioautographic localization of the increased synthesis of phosphatidylinositol in response to pancreozymin or acetylcholine in guinea pig pancreas slices. AB - A technique is described for measuring the incorporation of myo-inositol-2-(3)H into the lipid of various regions of the guinea pig pancreatic acinar cell by radioautography. Stimulation of enzyme secretion with either pancreozymin or acetylcholine was associated with increased graining in both the basophilic cytoplasm and the nonbasophilic cytoplasm. Kinetic studies suggested that the incorporation of myo-inositol-2-(3)H was stimulated independently in the two regions. Most of the increment in graining due to stimulation with pancreozymin or acetylcholine plus eserine was abolished if the tissue was extracted with 2:1 chloroform-methanol before radioautography. On chromatography of lipid extracts of pancreas, the only lipid showing a detectable increment in radioactivity on stimulation with pancreozymin was phosphatidylinositol. Thus, essentially all of the increment in graining is likely to be due to increased incorporation of tritium into phosphatidylinositol. These studies, coupled with earlier studies employing differential centrifugation, indicate that on stimulation of enzyme secretion there is increased synthesis of phosphatidylinositol in the rough surfaced endoplasmic reticulum and in the smooth-surfaced Golgi membranes. The significance of these observations is discussed in connection with membrane circulation presumed to occur in the pancreatic acinar cell on stimulation of protein secretion. It is suggested that the increased synthesis of phosphatidylinositol may be concerned with the formation of new endoplasmic reticulum and possibly Golgi membrane to replace that which is presumably converted to membrane of the zymogen granules during intracellular protein transport. PMID- 4292094 TI - Spin-label determination of enzyme symmetry. PMID- 4292092 TI - An in vitro effect of triiodothyronine on rat adipose tissue. AB - Triiodo-L-thyronine (T(3)) added in vitro to fat pads from normal, or propylthiouracil-treated rats enhanced the rate of release of glycerol and free fatty acids (FFA) in the presence of epinephrine. An effect of T(3) was also demonstrated in the presence of adrenocorticotropic hormone (ACTH), thyroid stimulating hormone, or glucagon in studies with tissue from normal rats. The minimal effective concentration of T(3) was approximately 2.5 x 10(-5) mole/liter for intact fat pads and 3 x 10(-6) mole/liter for fat cells. With fat pads from propylthiouracil-treated rats the effect of T(3) was not apparent until the 3rd hr of incubation. Enhancement of epinephrine-stimulated lipolysis by T(3) was evident during the 1st hr of incubation of fat pads from normal rats, and fat cells responded almost immediately to the presence of T(3). When added alone or in the presence of theophylline, 3',5'-adenosine monophosphate or its dibutyryl derivative, T(3) had little or no effect on lipolysis. The effect of T(3) was observed with or without glucose in the medium, and was not inhibited by cycloheximide or actinomycin D. It did not persist when tissues, after incubation in the presence of T(3) were transferred to medium without T(3). No effect of T(3) on glucose uptake in the presence of epinephrine, ACTH, or insulin was demonstrated. PMID- 4292093 TI - Experimental viral hepatitis in the dog: production of persistent disease in partially immune animals. AB - Experimental infection with canine hepatitis virus has been studied in a series of 49 dogs. The pattern of response to infection was distinctly modified by the immune status of the animal. All of 19 fully susceptible dogs had an acute, fulminating fatal hepatitis when infected with a standard dose of virus, and all of 19 dogs with high levels of immunity to the virus survived without apparent illness. However, 11 dogs were spontaneously encountered with partial immunity to the infectious agent, and these animals developed different, prolonged forms of hepatitis following infection. In four animals death occurred in 8-21 days following what may be called a subacute course. The remaining seven dogs survived up to 8 months with evidence of chronic hepatic damage. The subacute and chronic forms of hepatitis were reproduced experimentally in seven of eight fully susceptible dogs which were passively immunized against the canine hepatitis virus by administration of hyperimmune serum. Although the virus could be found in sites of hepatic damage in the early stages of the subacute and chronic diseases, it could not be demonstrated in the later stages which were characterized by persistent hepatic damage and a marked chronic inflammatory reaction. Dogs with chronic hepatitis eventually developed extensive hepatic fibrosis. The pathologic, physiologic, virologic, and immunologic features of these experimental forms of viral hepatitis are described. PMID- 4292095 TI - High-resolution electron spin resonance studies of hyperfine inter actions in substituted 1,4-naphthoquinones and naphthazarins. PMID- 4292096 TI - Electron paramagnetic resonance study of L-alanine irradiated at low temperatures. PMID- 4292097 TI - Trophoblastic disease. PMID- 4292098 TI - [Studies on the phosphate metabolism of dermatomyces]. PMID- 4292099 TI - Activation of production of infectious tumor virus SV40 in heterokaryon cultures. PMID- 4292100 TI - Spin-label study of hemoglobin conformations in solution. PMID- 4292101 TI - Carbohydrate transport in Staphylococcus aureus. V. The accumulation of phosphorylated carbohydrate derivatives, and evidence for a new enzyme-splitting lactose phosphate. PMID- 4292102 TI - Regulation of fructose diphosphatase activity by disulfide exchange. PMID- 4292103 TI - Japanese B encephalitis. Symptom dynamics in an organic psychosis. PMID- 4292104 TI - [The ultrathin structure of transplantable hepatomas of C3HA mice. II. An electron microscopic study of the ascitic form of hepatoma 22 and hepatoma 48]. PMID- 4292105 TI - [An electron microscopic study of cell contacts in ascitic and solid hepatomas]. PMID- 4292107 TI - Studies on infectious laryngotracheitis (ILT) virus. PMID- 4292106 TI - [A comparative study of aspartate aminotransferase in mitochondria and supernatant of mouse liver cells and certain mouse hepatomas]. PMID- 4292108 TI - Some observations on herpes virus mammillitis of bovine animals. PMID- 4292109 TI - Presence of type C virus particles and their aberrant form in mammary carcinoma of a strain C58 mouse. PMID- 4292110 TI - [Studies on prostatic phosphatase. I. Purification and immunologic certification of human prostatic phosphomonoesterase]. PMID- 4292111 TI - [Studies on the steroid excretion in a patient with a Cushing syndrome associated with a secondary myxedema due to hypophyseal tumor]. PMID- 4292112 TI - [Radiotherapy of brain tumors]. PMID- 4292113 TI - [Isotope diagnosis of brain tumors]. PMID- 4292114 TI - [The selective brain perfusion in cytostatic treatment of glioblastoma]. PMID- 4292115 TI - The properties of cell clones derived from a polyoma induced mouse tumor. PMID- 4292116 TI - [On the roentgenology of malignant synovialoma]. PMID- 4292117 TI - Sporulation of Clostridium perfringens (welchii) in four laboratory media. PMID- 4292118 TI - On the heredity of ESR spectra intensity of the human hair. PMID- 4292119 TI - [Salaam convulsions and subdural hygroma]. PMID- 4292120 TI - [Renin-angiotensin of spontaneously hypertensive rats]. PMID- 4292121 TI - [The antigenic and immunologic properties and relations of A subtypes of the foot and-mouth disease virus. II. After vaccination of guinea pigs with formalin adsorbate]. PMID- 4292122 TI - Structure and function of the mitochondria with a brief note on blood cell mitochondria. PMID- 4292123 TI - The effects of neuromuscular blocking agents on mitochondria. 3. Effects of D tubocurarine and pyrrolizidine alkaloids on the uptake and depletion of cations. PMID- 4292124 TI - Electron spin resonance study on the photoinduced radicals from carcinogenic 4 nitroquinoline 1-oxide. PMID- 4292125 TI - [Glomus tumors (nonchromaffin paragangliomas) of the ear]. PMID- 4292126 TI - Clinical effects of vinblastine on chorionic tumors. PMID- 4292127 TI - Angiofibroma of the ethmoidal sinus in a female. PMID- 4292128 TI - Zeta potential in the development of pharmaceutical suspensions. PMID- 4292129 TI - [Examinations for virus diseases. (3) Neutralization]. PMID- 4292130 TI - [Intense short-term corticoid therapy in epidemic hepatitis]. PMID- 4292132 TI - [Report of a case of hypophyseal metastasis of rectal carcinoma]. PMID- 4292131 TI - Antigenic response in cattle to Clostridium welchii type D vaccine. PMID- 4292133 TI - [Structure-dependent correlations of silicon compounds with drugs. 13. A report on the effect of auxiliary substances in the production of drug preparations]. PMID- 4292134 TI - Clostridal infection of the uterus. A review treatment with hyperbaric oxygen. PMID- 4292135 TI - [Studies on animal serum inhibitors against poliovirus. I. Specificities of cattle and horse serum inhibitors against polioviruses]. PMID- 4292136 TI - [Studies on animal serum inhibitors against poliovirus. II. The nature of the serum inhibitors and their mechanisms of inactivation of poliovirus]. PMID- 4292137 TI - Renin substrate in plasma under various experimental conditions in the rat. PMID- 4292138 TI - [Reflections on resection of the lower trachea and bronchial bifurcation]. PMID- 4292139 TI - The vitamin K content of beef liver. Detection of a new form of vitamin K. PMID- 4292140 TI - Vitamin D stimulation of [3H]orotic acid incorporation into ribonucleic acid of rat intestinal mucosa. PMID- 4292141 TI - Diphosphopyridine nucleotide specific isocitric dehydrogenase of mammalian mitochondria. I. On the roles of pyridine nucleotide transhydrogenase and the isocitric dehydrogenases in the respiration of mitochondria of normal and neoplastic tissues. PMID- 4292142 TI - Studies on the deproteinization of DNA. PMID- 4292143 TI - Synthesis of a polydeoxyribonucleotide containing an internal pyrophosphate linkage. PMID- 4292144 TI - The value of the electromyogram in the diagnosis of pressure neuropathy from "hanging arm". PMID- 4292145 TI - [[Intra-arterial infusion of anticancer agents for hepatic tumor and application of hepatography, with reference to an oil-soluble radiopaque agent]. PMID- 4292146 TI - Organic fluorine compounds. 3. Action of perchloryl fluoride on substituted ethyl cyanoacetates and animal toxicities of the fluorinated products. PMID- 4292147 TI - Methods of storing viruses at low temperatures with particular reference to the Myxovirus group. PMID- 4292148 TI - [Effect of ACTH upon the serum CPK activity in various neuromuscular diseases]. PMID- 4292149 TI - Mitochondrial polymorphism in maize. I. Putative evidence for de novo origin of hybrid-specific mitochondria. PMID- 4292150 TI - On the production of highly labeled tumor virus deoxyribonucleic acid. PMID- 4292151 TI - Studies on the locus of the enzyme recognition site in phenylalanine transfer RNA. PMID- 4292152 TI - The presence of adenovirus-specific antigens in hamster cells rendered neoplastic by adenovirus 1-SV40 and adenovirus 2-SV40 hybrid viruses. PMID- 4292154 TI - Value of the ninhydrin test in investigation of tactile sensitivity. PMID- 4292153 TI - Flavoproteins of the mitochondrial respiratory chain. PMID- 4292155 TI - Technetium-iron-ascorbic acid complex. A good brain scanning agent. PMID- 4292156 TI - Neuropathy following irradiation. An unusual late complication of radiotherapy. PMID- 4292157 TI - Oxidative phosphorylation in nuclei isolated from rat thymus. PMID- 4292158 TI - The cytochrome system of Bacillus megaterium KM. The presence and some properties of two CO-binding cytochromes. PMID- 4292159 TI - Reconversion of detergent- and sulfhydryl reagent-produced P-420 to P-450 by polyols and glutathione. PMID- 4292160 TI - The chemistry of flavins and flavoproteins. 3. The reaction of dihydrolipoic acid with flavins. PMID- 4292161 TI - On the possible role of structural protein in the binding and translocation of adenine nucleotides in mitochondria. PMID- 4292162 TI - Target size of components in oxidative phosphorylation. Studies with a linear accelerator. PMID- 4292163 TI - The effect of light on flavoproteins in the presence of alpha-keto acids. PMID- 4292164 TI - Electron spin resonance of cytochrome b2 and of cytochrome b2 core. PMID- 4292165 TI - Oxygen evolution by isolated chloroplasts with carbon dioxide as the hydrogen acceptor. A requirement for orthophosphate or pyrophosphate. PMID- 4292166 TI - ATPase activities of rat epididymal adipose tissue. PMID- 4292168 TI - [The formation of nicotinamide-adenine-dinucleotide from tryptophan after whole body irradiation]. PMID- 4292167 TI - Widespread necrotizing arteritis in rheumatoid arthritis: report of a patient who survived. PMID- 4292169 TI - On the central hypertensive effect of angiotensin II. PMID- 4292171 TI - Biosynthesis of urea. XII. Further studies on argininosuccinate synthetase: substrate affinity and mechanism of action. PMID- 4292172 TI - Electromagnetic properties of hemoproteins. I. Electron paramagnetic resonance absorptions of single crystals of ferrimyoglobin and cytochrome c peroxidase. PMID- 4292170 TI - Interactions of substrates, inhibitors, and coenzymes at the active site of horse liver alcohol dehydrogenase. PMID- 4292173 TI - Electromagnetic properties of hemoproteins. II. The effect of physical states on electron paramagnetic resonance parameters of hemoproteins. PMID- 4292174 TI - Histochemistry of hidradenoma and eccrine spiradenoma. PMID- 4292175 TI - [Electron microscopic localization of nucleoside phosphatase activity in plasma membrane of rat liver and hepatomas]. PMID- 4292176 TI - Hepatic lobectomy for teratoid liver cancer. Report of a seven-year cure. PMID- 4292177 TI - [Nasoalveolar cyst]. PMID- 4292179 TI - [Stress and the endocrinological structure--with special reference to the diencephalic-pituitary-adrenal system]. PMID- 4292178 TI - Intravascular coagulation and fibrinolysis in septic abortion. PMID- 4292180 TI - Phenotypic expression of transformation: induction in cell culture by a phorbol ester. AB - A biologically potent, tumor-promoting phorbol ester from Croton tiglium L. induces the appearance of transformed clones in a population of contact-inhibited fibroblasts of the mouse cell line 3T3. Mixed populations of cells with 10,000 3T3 cells and 100 virus-transformed cells were exposed to the phorbol ester and, in comparison with untreated cells, showed a marked increase in the numbers of transformed clones that grew. Exposure of 3T3 cultures to the carcinogen 7,12 dimethylbenz(a)anthracene alone or prior to exposure to the phorbol ester did not cause any increase in the number of transformed clones. PMID- 4292181 TI - Epithelial-mesenchymal interactions. PMID- 4292182 TI - The removal of non-specific inhibitors from human and animal sera to mumps and para-influenza type I viruses by kaolin. PMID- 4292183 TI - Experimental studies on continuous intra-arterial infusion of anti-tumor agents (with special emphasis on histochemical changes). PMID- 4292184 TI - Roentgen diagnosis in lymphedema. PMID- 4292185 TI - [Interaction between vasopressin and the sympathico-medullo-adrenal system]. PMID- 4292186 TI - [Studies on chemotherapy of trophoblastic tumors, especially on clinical and histological effects]. PMID- 4292187 TI - [Histochemical study of enzymes in the cervical cancer with special reference to the effect of radiation therapy]. PMID- 4292188 TI - [Hemostatic effect of Premarin]. PMID- 4292189 TI - [On a case of "unilateral mandibulofacial dysostosis"]. PMID- 4292190 TI - [Evaluation of angiotension skin test and the angiotensin infusion test]. PMID- 4292191 TI - The ultrastructure of a human glioblastoma multiforme-derived tumor heterologously transplanted to guinea pig eye and brain. PMID- 4292192 TI - [On the question of tertiary cerebrospinal tumors metastasizing via the choroid plexus]. PMID- 4292193 TI - Biochemical studies of otosclerosis: enzymes and protein in malleus and incus. PMID- 4292194 TI - Increased incidence of hepatoma in mice with chronic schistosomiasis mansoni treated with a carcinogen. PMID- 4292195 TI - Electron microscopy of a benign epidermal pox disease of rhesus monkeys. PMID- 4292196 TI - Single-strand scissions induced in circular and linear lambda DNA by the presence of dithiothreitol and other reducing agents. PMID- 4292197 TI - Collagen synthesis on polyribosomes of cultured mammalian fibroblasts. PMID- 4292198 TI - D-Tyrosyl RNA: formation, hydrolysis and utilization for protein synthesis. PMID- 4292199 TI - Physico-chemical studies of three variants of Mengo virus and their constituent ribonucleates. PMID- 4292200 TI - The progressive pressor response to angiotensin in the rabbit. AB - 1. The threshold for any detectable rise of systemic arterial pressure during the prolonged intravenous administration of angiotensin to conscious rabbits was observed to be an infusion rate of 0.003-0.006 mug.kg(-1).min(-1).2. At infusion rates between threshold and 0.04 mug.kg(-1).min(-1) the systemic arterial pressure rose progressively over a 3- to 7-day period to a plateau.3. On stopping the angiotensin infusion the blood pressure fell rapidly back to its base line much faster than it rose during the infusion. The time taken to reach control values was approximately related to the duration of the infusion.4. At infusion rates of about 0.05 mug.kg(-1).min(-1) the full rise of blood pressure developed within a few minutes, and could be sustained without change for many days. At higher rates the blood pressure diminished with time.5. Diurnal fluctuations of blood pressure were often seen during prolonged infusions of angiotensin at low rates; and more rapid fluctuations of blood pressure over an hour or two were frequently encountered immediately after an infusion was turned off.6. The possible role of angiotensin in producing chronic renal hypertension is discussed in the light of these observations. PMID- 4292201 TI - Acute renal failure caused by hypersensitivity to polymyxin B sulfate. PMID- 4292202 TI - [Tumor viruses and human cells]. PMID- 4292203 TI - Electrocardiographic abnormalities and some myocardial enzymatic disturbances in experimental poisoning with metallic mercury. PMID- 4292205 TI - Comparison of adrenocortical reserves with long-acting corticotropin preparations in the two-day intramuscular corticotropin test in man. PMID- 4292204 TI - Treatment of peripheral nerve injuries. PMID- 4292206 TI - Fluorimetric determination of corticosteroids in human plasma. PMID- 4292207 TI - Chemical bonding information from photoelectron spectroscopy. AB - High-resolution measurements of photoelectrons produced by x-rays in compounds of iodine and europium have revealed chemical shifts in the core-level energies, from which chemical bonding information can be obtained. The observed shifts, 0.8 electron volt per unit change in oxidation number in iodine and 9.6 electron volts in europium, are discussed in terms of two theoretical models. PMID- 4292208 TI - [Changes in the metabolism and ultrastructure of brain mitochondria under the influence of aminazine]. PMID- 4292209 TI - [The effects of some aminoazo compounds on isolated liver cells, ascitic hepatoma and Ehrlich ascitic carcinoma]. PMID- 4292211 TI - [Tryptic lysis of cells as a test of the condition of cytoplasmic membrane phospholipids]. PMID- 4292210 TI - [The distribution of acid phosphatase activity in the ultrastructures of liver cells during the development of induced hepatoma]. PMID- 4292212 TI - [On tryptophan pyrrolase activity in minimal hepatomas of C3HA mice under the effects of cortisone]. PMID- 4292213 TI - Cellular immunity factors in infection with polyoma virus. I. Levels of inhibitors of the polyoma virus and interferon-like substances in organs and tumors in hamsters infected with polyoma virus. PMID- 4292214 TI - Studies on the etiology of viral hepatitis (VH). I. Isolation attempts of the etiologic agent by various methods. PMID- 4292215 TI - Studies on the etiology of viral hepatitis. II. Media stimulating growth of viruses. PMID- 4292216 TI - Goltz's syndrome: focal dermal hypoplasia. A combined mesoectodermal dysplasia. PMID- 4292217 TI - A comparison of normal red cell ATP levels as measured by the firefly system and the hexokinase system. PMID- 4292218 TI - Myxovirus influenza A isolated from ducklings. AB - A strain of haemagglutinating virus isolated by Walker and Bannister in 1953 and identified by them as "Filterable Agent" of ducks has been examined. The evidence suggests that although belonging to the Myxovirus Influenza Type A group, it possesses specific strain properties. PMID- 4292220 TI - Effectiveness of irradiation therapy in peripheral neuropathy caused by malignant disease. PMID- 4292219 TI - Selective heat sensitivity of cancer cells. Biochemical and clinical studies. PMID- 4292221 TI - "Mesenchymal" chondrosarcoma, a rare malignant chondroid tumor usually primary in bone. Report of a case arising in extraskeletal soft tissue. PMID- 4292222 TI - Prediction of adult stature. PMID- 4292223 TI - Radioimmunoassays. II. An evaluation of the use of radioimmunoassay for the measurement of protein hormones. PMID- 4292224 TI - Functional adrenocortical carcinoma in a dog. PMID- 4292225 TI - Studies on the chemistry of hemoglobin. II. The effect of salts on the dissociation of hemoglobin into subunits. PMID- 4292226 TI - The purification and properties of a thyroid-stimulating factor isolated from Clostridium perfringens. PMID- 4292227 TI - Lipid composition of mitochondria from bovine heart, liver, and kidney. AB - Highly purified preparations of mitochondria from bovine heart, liver, and kidney were isolated and characterized by electron microscopy, oxidative phosphorylation ability, cytochrome c reductase activity, and cytochrome content. Components of lipid extracts of the preparations were determined by thin-layer chromatography, diethylaminoethyl-cellulose column chromatography, and spectrophotometric procedures. The major phospholipids were identified by their chromatographic behavior, IR spectrometry, and paper chromatography of their hydrolysis products. The lipid content of the mitochondria paralleled that of the components of the electron transfer chain, heart mitochondria being richest and liver mitochondria poorest in lipid. Heart mitochondria contain equal concentrations of coenzyme Q and cholesterol (1%); the highest cholesterol content (4.7%) was found in mitochondria from kidney. The phospholipids of mitochondria from the three organs were qualitatively and quantitatively very similar. The major polar lipid components (cardiolipin, choline glycerophosphatides, and ethanolamine glycerophosphatides) were present in a molar ratio of 1:4:4. It is suggested that mitochondria from different sources contain characteristic lipids, mainly phospholipids, of which cardiolipin is particularly diagnostic of the source of the mitochondria. PMID- 4292229 TI - Removal of the sphingolipid impurity from preparations of yeast phosphatidyl inositol. AB - A complex sphingolipid containing inositol and mannose, present in lipid extracted from toluene-autolyzed baker's yeast, was eluted from silicic acid columns immediately after phosphatidyl inositol, and was the main nitrogenous impurity in crude preparations of this phospholipid. Nitrogenfree phosphatidyl inositol was obtained by rechromatography on alumina. Modifications to the chromatographic procedure also gave diphosphatidyl glycerol containing the theoretical 4.29% P. PMID- 4292228 TI - Biosynthesis of retinoic acid by intestinal enzymes of the rat. AB - The incubation of beta-carotene-(14)C with the soluble fraction of the intestinal mucosa resulted in the formation of small amounts of acidic material. The addition of NAD or NADH to the soluble fraction caused a tenfold increase in this material. Incubation of retinal-15-(14)C with the soluble fraction of the intestinal mucosa plus NAD or NADH resulted in the conversion of 80-90% of the retinal to acidic material, which has been shown to contain retinoic acid. In vivo studies on the formation of retinoic acid in the intestinal mucosa after the administration of beta-carotene-(14)C revealed that an appreciable amount of beta carotene was converted to acidic compounds. When retinal-15-(14)C was administered, portal blood contained 30-40% of the absorbed radioactivity. 24% of this radioactivity was found in acidic material, which has been shown to contain retinoic acid. It is suggested that enzymes in rat intestine cleave beta-carotene to retinal and oxidize the latter to retinoic acid, which is then transported via the portal circulation to the liver. PMID- 4292230 TI - [Pregnancy, pregnancy disorders, and the problem of trophoblastic tumors, from the viewpoint of new immunobiological studies]. PMID- 4292231 TI - Complement fixation test of equine infectious anemia. I. Specificity of the test. PMID- 4292232 TI - Complement fixation test of equine infectious anemia. II. Relationship between CF antibody response and the disease. PMID- 4292233 TI - Specific complement fixation test of Rous sarcoma with pigeon serum. PMID- 4292234 TI - Mixed infection with avian adenovirus and fowl pox virus. PMID- 4292235 TI - [Chromolymphangiography and lymphangiography]. PMID- 4292236 TI - Clinical and therapeutic aspects of schistosomiasis. PMID- 4292237 TI - [On the prognosis of cylindroma]. PMID- 4292239 TI - Adrenocorticotrophic activity in plasma of patients with acromegaly. PMID- 4292238 TI - Plasma renin activity in hypertension. PMID- 4292240 TI - Dissecting perforation of infarcted interventricular septum with associated posterior papillary muscle involvement. PMID- 4292241 TI - Value of perlingual lymphography in cancer of the head and neck. A means of exploration of the lymphatic system of the neck. PMID- 4292242 TI - [Radioisotope test of vascular reactivity to angiotensin]. PMID- 4292243 TI - Subdiaphragmatic infection. PMID- 4292244 TI - Bronchography during infancy and childhood. PMID- 4292246 TI - Dissociation between inhibition of movement and inhibition of division in RSV transformed human fibroblasts. PMID- 4292245 TI - Oxidoreductive and hydrolytic enzyme patterns in plant suspension culture cells. Local and time relationships. PMID- 4292247 TI - Aminoglutethimide (Elipten-Ciba) as an inhibitor of adrenal steroidogenesis: mechanism of action and therapeutic trial. PMID- 4292248 TI - Circulating viral and thyroid antibodies in subacute thyroiditis. PMID- 4292249 TI - Cushing's syndrome in association with a carcinoid tumor of the lung. PMID- 4292250 TI - Effect of estrogen therapy on carbohydrate metabolism in acromegaly. PMID- 4292251 TI - Failure of metyrapone to inhibit 11-hydroxylation of 11-deoxycortisol during drug therapy. PMID- 4292252 TI - Gastric mucosal injury by anti-inflammatory drugs. PMID- 4292253 TI - Hormone-secreting tumours of the pancreas. PMID- 4292254 TI - Electron spin resosnance of gamma-irradiated oriented DNA prepared by wet spinning. AB - When moist, oriented DNA is gamma-irradiated and its electron spin resonance spectrum is recorded at 77 degrees K, an unresolved spectrum is obtained, the amplitude of which is strongly dependent on the angle between the direction of the DNA helices and the field. Annealing at 199 degrees K gives an eight-line thymine-like spectrum which also has a marked angular dependence. For dry, oriented DNA, the unresolved spectrum dominates even at room temperature, and the spectra exhibit lower degrees of anisotropy. PMID- 4292255 TI - Tissue specificity of histone phosphorylation. AB - The incorporation of (32)P-phosphate into histone fractions isolated from normal, hepatectomized, and Novikoff hepatoma-bearing rats was investigated. Varying degrees of phosphorylation were exhibited by different histone fractions. The phosphorylation of histones is tissue specific and appears to be correlated with metabolic cell functions, that is, it decreases with increasing mitotic activity of the cells. PMID- 4292256 TI - [Congenital tumors of the gingiva in newborn infants]. PMID- 4292257 TI - [Inhibitory action of vitamin D3 on the succinic dehydrogenase activity in several animal tissues]. PMID- 4292259 TI - [Qualitative and quantitative immunological variations in children immunized with Sabin type live poliomyelitis vaccine by 2 immunization schedules]. PMID- 4292258 TI - [The combined treatment of gas gangrene. IV. Histopathological lesions in experimental Clostridium perfringens infections in white mice and their normal dynamics as well as those under the influence of certain combined therapies]. PMID- 4292260 TI - [Excretion of poliomyelitis virus types 1, 2 and 3 before and after vaccination with the Sabin vaccine in children's institutions]. PMID- 4292262 TI - [Typing of the foot-and-mouth disease virus, Nong-Sarai (Thailand). Results of diagnosis and typing of the foot-and-mouth disease virus]. PMID- 4292261 TI - [On electroclinical correlation in epilepsy]. PMID- 4292263 TI - [Bordetella pertussis and parapertussis. A comparison of the effects of chloramphenicol and other antibiotics in vitro]. PMID- 4292264 TI - An estrogen-producing "yellow tumour" of the ovary associated with arterial hypertension. (A case report contributing to the problem of classification of functioning ovarian neoplasms). PMID- 4292265 TI - Adenovirus infections in Indian army personnel. PMID- 4292266 TI - [Sarcomas of the uro-genital sinus in boys]. PMID- 4292267 TI - Investigation of treatment for jaundice in newborn infants. PMID- 4292268 TI - The mechanism of contracting action of angiotensin on the isolated aortic strip of rabbit. PMID- 4292270 TI - [Synovioblastoma of the palm in a difficult judicial evaluation]. PMID- 4292269 TI - [Contribution of lymphadenography to the prognosis of Hodgkin's disease]. PMID- 4292271 TI - [A rare case of glomangioma on the leg]. PMID- 4292272 TI - [Apropos of surgery of tumors of the trachea]. PMID- 4292273 TI - Pharmacology and diagnosis of pesticide-induced illnesses. AB - Although emphasis upon the concept of environmental health is a recent development in the medical community at large, the environment in which man worked has been of considerable concern to physicians in occupational medicine for a quarter of a century or more. Among the environmental factors which may adversely affect the health of exposed persons are the pesticides. The pharmacologic properties of these chemicals as well as the diagnostic signs and symptoms are presented herein. PMID- 4292274 TI - [Studies on resistance of tubercle bacilli to reserve drugs. II. Resistance to viomycin and kanamycin in experimenta tuberculosis in guinea pigs]. PMID- 4292275 TI - [New knowledge in the field of endocrinology]. PMID- 4292276 TI - Cardiac accelerator mechanisms of angiotensin. PMID- 4292277 TI - Effect of carzinophilin on the metabolism of nicotinamide adenine dinucleotide in the Ehrlich ascites cells in vitro. PMID- 4292278 TI - Demonstration of Entamoeba histolytica from liver biopsy specimen. PMID- 4292279 TI - [Autopsy case of stomach cancer characterized by calcium deposit]. PMID- 4292280 TI - [Wilms tumor, clinical report on 29 cases]. PMID- 4292281 TI - [On the problem of nutritional control of adrenal cortex function]. PMID- 4292282 TI - [Silicosis and dissolution of silicon dioxide]. PMID- 4292283 TI - [Value of the oligobiopsy of the salivary gland tumors]. PMID- 4292284 TI - [Effect of chronic administration of luminal on the histologic and histochemical pattern of the exocrine part of the pancreas in rats]. PMID- 4292285 TI - [Critical evaluation of radiographic methods of determination of bone age]. PMID- 4292286 TI - [Importance of cytologic examination of mammary secretion in the early diagnosis of breast cancer (25 cases)]. PMID- 4292287 TI - Juvenile nasopharyngeal angiofibroma. (Report of a case with unusual features). PMID- 4292288 TI - Cell transformation of established human cell line induced by SV-40 DNA. PMID- 4292289 TI - Effect of ACTH and prednisolone on Japanese encephalitis. PMID- 4292290 TI - Chemotherapy of glioblastoma multiforme: an appraisal. PMID- 4292291 TI - [Action of pantetheine on the adrenal cortex]. PMID- 4292292 TI - [Structure-specific degradation of polypeptide-metal complexes. IV. Degradation of Ni2-polymyxin -B-complexes by H202]. PMID- 4292293 TI - Studies in the reliability of assessing skeletal maturity from x-rays. 3. Greulich-Pyle Atlas and Tanner-Whitehouse method contrasted. PMID- 4292294 TI - Salicylic acid in the treatment of diabetic, neurotrophic and ischemic ulcers. PMID- 4292295 TI - Effect of progressive starvation on rat liver enzyme activities. PMID- 4292297 TI - [Studies of the particle size distribution of suspensions of silica by a turbidimeter with an integrating sphere]. PMID- 4292296 TI - Aspects of liver lipid metabolism in the biotin-deficient rat. PMID- 4292298 TI - [Study of a medium for the isolation and identification of Clostridium perfringens]. PMID- 4292299 TI - [Anogenital Paget's disease]. PMID- 4292300 TI - Simultaneous determination of renin activity and angiotensin concentration levels in human plasma. PMID- 4292301 TI - Respiratory syncytial virus infections in families. A study of family members of children hospitalized for acute respiratory disease. PMID- 4292302 TI - Homeostatic role of the renal-adrenal axis in bacteremic shock. Its therapeutic implications. PMID- 4292303 TI - Myelin artifacts. PMID- 4292304 TI - Studies of a biochemical lesion in experimental tuberculosis in mice. V. Further study on a toxic lipid fraction in firmly bound lipids. PMID- 4292305 TI - Eosinopenic response of asthmatic children to ACTH. PMID- 4292306 TI - The place of corticosteroids in pulmonary disease. PMID- 4292307 TI - Multiple granular cell myoblastomas in children. PMID- 4292308 TI - Autoimmune progesterone urticaria. PMID- 4292309 TI - [Effects of subsequent inoculation with virus SV40 on the transplantation of cells transformed by this virus]. PMID- 4292310 TI - Virus transfer through a sewage disposal unit. PMID- 4292311 TI - Lethal toxin of Bacillus cereus. I. Relationships and nature of toxin, hemolysin, and phospholipase. AB - Bacillus cereus phospholipase was characterized as a phospholipase C by the analysis of lecithin degradation products by thin-layer and paper chromatography. Methanol in the growth menstruum inhibited completely the synthesis of phospholipase C, whereas the synthesis of lethal toxin and hemolysin were only partially inhibited. Dialysis of preformed B. cereus products against ethyl alcohol and methanol did not inactivate hemolytic, phospholipase C, or lethal activity. The hemolytic and lethal activities of culture filtrates were completely abolished by trypsin, but phospholipase C activity was resistant to inactivation. Lethal and phospholipase C properties of culture filtrates were resistant to inactivation at 45 C, whereas the hemolytic activity was completely destroyed. Lethal, hemolytic, and phospholipase C activities appeared simultaneously in a complex growth menstruum, but the kinetics of synthesis were different in all cases. Resolution of B. cereus filtrates on columns of Sephadex showed that the phospholipase C, hemolysin, and lethal toxin are distinct proteins. Evidence is also presented which suggests a correlation between the synthesis of B. cereus toxin and the period of transition from vegetative growth to sporulation. The activity of each B. cereus product was cation-independent, as opposed to cation-dependency of the phospholipase C and lethal activities of Clostridium perfringens alpha-toxin. Immunological cross-reactivity between the B. cereus products and C. perfringens alpha-toxin was not apparent; indeed, they were shown to be antigenically distinct. PMID- 4292312 TI - Effect of adenosine monophosphate, adenosine diphosphate, and reduced nicotinamide adenine dinucleotide on adenosine triphosphate-dependent carbon dioxide fixation in the autotroph Thiobacillus neapolitanus. AB - The observation that adenosine triphosphate (ATP)-dependent CO(2) fixation in extracts of chemosynthetic and photosynthetic autotrophs may be regulated in part by adenosine monophosphate (AMP) was extended to the strict autotroph Thiobacillus neapolitanus (X). In addition, this report presents data which include adenosine diphosphate (ADP) in the regulatory role. When the primary CO(2) acceptor, ribose-5-phosphate, was replaced by ribulose-1,5-diphosphate, no inhibition of CO(2) fixation occurred unless the Mg(++) concentration was limiting. A molar ratio of 5:1 AMP or ADP to ATP reduced the specific activity (micromoles of CO(2) fixed per milligram of protein per minute) of the extracts from 0.22 to 0.12 and 0.11, respectively. The reported stimulation of the carboxylative phase of ATP-dependent CO(2) fixation by reduced nicotinamide adenine dinucleotide (NADH(2)) was investigated. Adding NADH(2) to the extracts did not stimulate CO(2) fixation, even at carbonate levels from 0.05 to 30 mumoles, except in the absence of ribose-5-phosphate. Slight increases in CO(2) fixation were noted when the assay system was incubated in air instead of the usual helium atmosphere. PMID- 4292313 TI - Fine structure of the cytomembranes of Nitrosocystis oceanus. AB - Thin-sectioned, negatively stained, and freeze-etched preparations of Nitrosocystis oceanus cytomembranes were compared. The cytomembranes in freeze etched cells were covered with 80- to 120-A particles. When cells were disrupted and differentially centrifuged, various membrane and particle fractions were obtained. Negatively stained membrane fragments from the pellet centrifuged at 3,000 x g showed 70- to 80-A stalked particles, whereas those from the pellet centrifuged at 39,000 x g exhibited a crystalline array of subunits with a 30- to 40-A periodicity. High-speed supernatant and pellet fractions centrifuged at greater than 39,000 x g contained 40- to 120-A free particles but no membranes. In chemically fixed cells, 40-A particles were found embedded in the matrix of membranes. Results suggest that the larger 80- to 120-A particles are enzyme complexes, whereas the smaller 30- to 40-A particles represent a structural protein or a lipoprotein of the membrane. PMID- 4292315 TI - Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes. AB - The response of rat liver lysosomes to an intraperitoneal injection of glucagon has been evaluated from studies on the mechanical fragility, osmotic sensitivity, and sedimentation properties of these subcellular particles. It has been found that about (1/2) hr after the injection of glucagon the hepatic lysosomes exhibit a fairly sudden increase in their sensitivity to mechanical stresses and to exposure to a decreased osmotic pressure. At the same time, their sedimentation properties undergo complex changes characterized mainly by a significant increase in the sedimentation coefficient of a considerable proportion of the total particles. In addition, glucagon causes an increase in the proportion of slowly sedimenting particles, with the result that the distribution of sedimentation coefficients within the total population tends to become bimodal. The latter change is more pronounced for acid phosphatase, less so for cathepsin D, and barely detectable for acid deoxyribonuclease. All these modifications are maximal between 45 and 90 min after injection and regress to normal within approximately 4 hr. With the exception of the increase in the slow component, for which no explanation can be advanced at the present time, they are consistent with the hypothesis that glucagon causes an increase in lysosomal size, and may be related to the autophagic-vacuole formation known to occur after glucagon administration. PMID- 4292317 TI - ESR studies of electron transfer: trans-stilbene-stilbene-system. PMID- 4292314 TI - Lysosomes and GERL in normal and chromatolytic neurons of the rat ganglion nodosum. AB - The rat ganglion nodosum was used to study chromatolysis following axon section. After fixation by aldehyde perfusion, frozen sections were incubated for enzyme activities used as markers for cytoplasmic organelles as follows: acid phosphatase for lysosomes and GERL (a Golgi-related region of smooth endoplasmic reticulum from which lysosomes appear to develop) (31-33); inosine diphosphatase for endoplasmic reticulum and Golgi apparatus; thiamine pyrophosphatase for Golgi apparatus; acetycholinesterase for Nissl substance (endoplasmic reticulum); NADH tetra-Nitro BT reductase for mitochondria. All but the mitochondrial enzyme were studied by electron microscopy as well as light microscopy. In chromatolytic perikarya there occur disruption of the rough endoplasmic reticulum in the center of the cell and segregation of the remainder to the cell periphery. Golgi apparatus, GERL, mitochondria and lysosomes accumulate in the central region of the cell. GERL is prominent in both normal and operated perikarya. Electron microscopic images suggest that its smooth endoplasmic reticulum produces a variety of lysosomes in several ways: (a) coated vesicles that separate from the reticulum; (b) dense bodies that arise from focal areas dilated with granular or membranous material; (c) "multivesicular bodies" in which vesicles and other material are sequestered; (d) autophagic vacuoles containing endoplasmic reticulum and ribosomes, presumably derived from the Nissl material, and mitochondria. The number of autophagic vacuoles increases following operation. PMID- 4292316 TI - ENDOR study of irradiated histidine HCl. PMID- 4292318 TI - ESR of free-radical conversion in gamma-irradiated dihydrothymine. PMID- 4292321 TI - [Trial treatment of acute leukemia and Hodgkin's disease with rubidomycin (or daunomycin) alone or in combination]. PMID- 4292319 TI - [Polycystic ovaries. I. Experimental basis, clinical data and biochemistry (apropos of 102 cases)]. PMID- 4292320 TI - [Polycystic ovaries. II. Therapeutic data (apropos of 102 cases)]. PMID- 4292322 TI - [Metabolic and circulatory resuscitation of the normal term newborn infant]. PMID- 4292323 TI - [Hypochromic anemia in adults]. PMID- 4292324 TI - [Effects of deoxyribonuclease I and phosphodiesterase obtained from snake's venom on living Hep-2 cells]. PMID- 4292325 TI - [A quantitative study of proliferating normal and tumor liver cells of rats and mice. I. Cytophotometric investigations on the regulation of cell metabolism in living isolated cells of regenerating rat liver]. PMID- 4292326 TI - Paget's disease of the scrotum. A case report. PMID- 4292327 TI - [Surgery of pontine glioma]. PMID- 4292329 TI - [Pulmonary cirulation and respiration during administration of hypertensin]. PMID- 4292328 TI - The effect of lipid micelles on mitochondrial malate dehydrogenase. PMID- 4292331 TI - [Study of the induction mechanism in Syrian hamster cells transformed by SV40 virus. I. Properties of a clonal cell line]. PMID- 4292330 TI - The effect of Rous Sarcoma virus (Schmidt-Ruppin strain) on the chromosomes of human leucocytes in vitro. PMID- 4292332 TI - Chromatography of polar triglycerides on silicic acid columns. PMID- 4292333 TI - [Recent contributions to the knowledge of epidemic keratoconjunctivitis]. PMID- 4292334 TI - [Paralysis due to nervous pressure "without" trauma]. PMID- 4292335 TI - [On the carotid angiography with oily products]. PMID- 4292336 TI - Temporary survival in clostridial hemolysis with absence of circulating red cells. PMID- 4292337 TI - Screening of antibacterial agents for in vivo activity against pseudomonas infection. PMID- 4292338 TI - Isolation of noninfectious particles containing Rous sarcoma virus RNA from the medium of Rous sarcoma virus-transformed nonproducer cells. PMID- 4292339 TI - Deoxyribonucleoproteins from the ciliate Tetrahymena pyriformis GL. PMID- 4292340 TI - Inactivation, by UV-, x-, and gamma-radiations, of the infecting and transforming capacities of polyoma virus. PMID- 4292341 TI - DEAE-dextran: enhancement of cellular transformation induced by avian sarcoma viruses. PMID- 4292342 TI - A viral interference test for mouse leukemia viruses. PMID- 4292343 TI - Efficient, inefficient, and abortive infection of different mammalian cells by small RNA viruses. PMID- 4292345 TI - [The Radioautography as a means for the determination of the electrophoretic mobility of culture virus and for testing the purity degree of virus preparations]. PMID- 4292344 TI - An interferon antagonist: its effect on interferon action in mengo-infected Ehrlich ascites tumor cells. PMID- 4292346 TI - [Investigations of the pituitary reserve in diabetes]. PMID- 4292347 TI - Granular cell myoblastoma of the tongue. PMID- 4292348 TI - Cancer in children--Wilms's tumor. PMID- 4292349 TI - [Nephrology]. PMID- 4292350 TI - [Studies on Clostridium welchii as one of the bacterial flora of normal human feces. 1. Bacterial count of total and heat-resistant organisms]. PMID- 4292351 TI - [Adrenocortical physiopathological aspects in gastric and duodenal ulcer]. PMID- 4292352 TI - [The determination of free SiO2 and total Si in atmospheric dusts using precipitation paper chromatography]. PMID- 4292353 TI - Excretion of testosterone and 17-ketosteroids following administration of HCG and ACTH to normal adult males. PMID- 4292354 TI - Biosynthetic studies of human ovarian arrhenoblastomatous tissue in vitro. I. Sulfatase and sulfokinase activity. PMID- 4292355 TI - Biosynthetic studies of human ovarian arrhenoblastomatous tissue in vitro. II. Formation of androgens from dehydroisoandrosterone sulfate. PMID- 4292356 TI - Metabolism of testosterone-4-C14 by rat brain homogenates and subcellular fractions. PMID- 4292357 TI - [An experimental study on atypical coarctation of the aorta with special reference to pressure mechanism in hypertension]. PMID- 4292358 TI - [Identification of Bordetella pertussis by fluorescent antibodies on microcolony impressions]. PMID- 4292359 TI - [The hemagglutinin of Myxovirus parainfluenzae. 3. The influence of some physical and chemical factors on hemagglutination]. PMID- 4292360 TI - [Serologic investigation for the demonstration of antibodies against the rhinopneumonitis virus (viral agent of abortion in mares) in studs]. PMID- 4292361 TI - [Enzyme histochemical study of experimentally induced uterine cancer in mice]. PMID- 4292362 TI - [Sepsis with Clostridium perfringens after gastrectomy]. PMID- 4292364 TI - [Enzymatic system of the ACTH target organ--the adrenal cortex]. PMID- 4292363 TI - [Structure and activity of ACTH]. PMID- 4292365 TI - Primary hepatoma 31 years after injection of thorotrast. PMID- 4292366 TI - Krukenberg tumours in pregnancy. PMID- 4292367 TI - [Adenovirus infections]. PMID- 4292368 TI - DPN (NAD-oxidized form): a preliminary evaluation in chronic schizophrenic patients. PMID- 4292369 TI - Serological reactions in sheep pox. I. Complement fixation test. PMID- 4292370 TI - Biological characteristics of primary tumors induced by polyoma virus in hamsters. PMID- 4292371 TI - Absence of specific chromosome alterations in bovine lung fibroblasts exposed to Rous sarcoma virus. PMID- 4292372 TI - Comparative study of angiotensin and nor-adrenaline in hypotensive states (shock). PMID- 4292374 TI - A clinicopathological conference from the Ohio State University Hospital, Columbus, Ohio. PMID- 4292373 TI - Growth failure. PMID- 4292375 TI - Benign lumbosacral radicular pain; a neurosurgeon's approach. PMID- 4292376 TI - The epidemiology of Clostridium welchii food poisoning. PMID- 4292377 TI - [Enzymatic activity in leptomeninges]. PMID- 4292378 TI - [Rules of a proper corticoid therapy in the treatment of uveitis]. PMID- 4292379 TI - [A method for the objective assessment of the potential ACTH reserve in the pituitary gland]. PMID- 4292380 TI - [Experience in the treatment of pharyngoconjunctival fever]. PMID- 4292381 TI - [A thermostabile inhibitor in pig serum against foot-and-mouth disease virus. 1. Occurrence and properties determinable in vitro]. PMID- 4292382 TI - The use of dimethyl sulfoxide in the treatment of genitourinary disorders. PMID- 4292383 TI - Trophocarcinoma of the testis. A report of eleven cases. PMID- 4292384 TI - Case notes. Value of ACTH in nonspecific optic neuritis. PMID- 4292385 TI - Diarrhea in infants: the role of viruses in the etiology of infantile diarrhea. PMID- 4292386 TI - Effects of adrenohypophyseal hormones upon urinary excretion of glucuronic acid and ascorbic acid. PMID- 4292387 TI - [Venous reno-portal anastomoses on dogs with Goldblatt kidneys]. PMID- 4292388 TI - [Wagner-Hepp-Unverricht disease (dermatomyositis). Analytical study of personal observations]. PMID- 4292390 TI - Respiratory infection of cattle associated with Myxovirus parainfluenza 3. PMID- 4292389 TI - Infectious bovine rhinotracheitis--a summary of the disease and its control with emphasis on New Zealand conditions. PMID- 4292392 TI - [Hemangioma sclerosans (histiocytoma) of the lung in a 52-year-old woman]. PMID- 4292391 TI - [Continuous fluorometric determination of pyruvic acid]. PMID- 4292393 TI - [2 cases of anterior tibial artery syndrome]. PMID- 4292394 TI - [Contributions to the occurrence and changes in intracytoplasmic filaments in gliomas]. PMID- 4292395 TI - Polyoma-like virions in a human demyelinating disease. PMID- 4292396 TI - [Comparative studies of the morphology and genesis of so-called medulloblastomas]. PMID- 4292397 TI - Mobility-molecular weight relationships of small proteins and peptides in acrylamide-gel electrophoresis. PMID- 4292398 TI - Simultaneous onset of Addison's disease and diabetes mellitus. A case report. PMID- 4292399 TI - Adrenergic blockade of hormone-induced lipolysis in isolated fat cells. PMID- 4292400 TI - Prostaglandins as adrenergic antagonists. PMID- 4292401 TI - Inhibition of mitochondrial respiration by progesterone and an azasteroid. PMID- 4292402 TI - Plasma angiotensinase activity on angiotensin II and analogues. PMID- 4292403 TI - Reversal by methoxyethylmercury intoxication of NAD induced activation of glutamate dehydrogenase from rat liver. PMID- 4292404 TI - An enzymatic model for some effects of methyoxyethylmercury acetate on rat liver glutamate dehydrogenase. PMID- 4292405 TI - Sodium sulphomethyl derivatives of polymyxins. PMID- 4292406 TI - [Inhibiting action of 9-beta-D-xylofuranosyl-adenine on the multiplication of herpes virus in cell culture]. PMID- 4292407 TI - Factors affecting the incorporation of precursors into the phospholipids of Ehrlich ascites cells. PMID- 4292408 TI - Effect of angiotensin on the release of acetylcholine from preganglionic and postganglionic nerve endings. PMID- 4292409 TI - A study of the origin of vitamin-D from 7-dehydrocholesterol in fish. PMID- 4292410 TI - Glycogenesis in the guinea pig liver during development. PMID- 4292411 TI - The influence of the experimental conditions on the renal response to angiotensin in the rat. PMID- 4292413 TI - Base composition of nonsense codons in Escherichia coli II. The N2 codon UAA. PMID- 4292412 TI - The influence of perathiepine and chlorpromazine on some enzyme reactions in rat brain preparations. PMID- 4292414 TI - The intralymphatic administration of radioactive isotopes in the overall treatment of malignant melanoma. PMID- 4292415 TI - Inhibition of stromal enzymes by x-radiation. PMID- 4292416 TI - Substrate specificity and stereospecificity of alcohol dehydrogenases. PMID- 4292417 TI - Cyclic 3',5'-nucleotide phosphodiesterase: localization and latent activity in rat brain. PMID- 4292419 TI - [Icterogenic hepatitis during septicemia caused by gram-negative bacillus (paracolon aerobacter)]. PMID- 4292418 TI - Catecholamine-secreting tumours. PMID- 4292420 TI - [Neonatal meningitis]. PMID- 4292421 TI - [Mixed salivary gland tumor located in the subfascia]. PMID- 4292422 TI - [Alkaline glycerophosphatase activity induced by the application of estrogen on the teat of the male guinea pig]. PMID- 4292423 TI - Steroids in gastrointestinal disease. PMID- 4292424 TI - [Secondary reactions of some new antibiotics. Viomycin]. PMID- 4292425 TI - Susceptibility of the East African red-tail monkey kidney cells to Enteroviruses. PMID- 4292426 TI - [A case of cylindroma at the root of the tongue and the pharynx with adenoma of the thyroid]. PMID- 4292427 TI - [Histological and histochemical study on the digestive tract of the loach (Misgurnus anguillicaudatus)]. PMID- 4292428 TI - [Serum calcium level and phosphorus excretion in classical infantile rickets]. PMID- 4292429 TI - [A case of traumatic rupture of Wilms' tumor in a 3-years-old child]. PMID- 4292430 TI - Hepatoblastoma presenting as an acute abdomen. PMID- 4292431 TI - Treatment of nephrotic syndrome. PMID- 4292432 TI - [Mixed tumors of epidermal salivary gland type]. PMID- 4292433 TI - [Brennenmann's syndrome]. PMID- 4292434 TI - [Isolation of rhinopneumonitis virus from aborted horse fetuses in Austria]. PMID- 4292435 TI - [Study on changes in adrenocortical function in long-term administration of glucocorticosteroids in small doses]. PMID- 4292436 TI - Enzymatic development of human fetus; studies on cytochrome oxidase and succinic dehydrogenase in developing human fetus. PMID- 4292437 TI - [Excretion of free and conjugated cortisol in adrenal cortex hyperfunctions]. PMID- 4292438 TI - Comparative study of nicotinamide adenine dinucleotide nucleosidase from Mycobacterium tuberculosis H37Rv & pig brain: effect of isonicotinic acid hydrazide on the enzyme-inhibitor complex. PMID- 4292439 TI - [Diagnosis of Japanese encephalitis by the fluorescent antibody method]. PMID- 4292440 TI - [Anesthesia in cardiac surgery. 4. Complications during and after the surgery. (1)]. PMID- 4292441 TI - [Case of glomus tumor of the stomach]. PMID- 4292442 TI - [Ovarian hilus cell tumor]. PMID- 4292443 TI - [The Kaplan-Silah test in the diagnosis of renovascular hypertension]. PMID- 4292444 TI - [The juxtaglomerular apparatus: physiopathology and clinical aspects of renin angiotensin system]. PMID- 4292445 TI - Hepatoma with rupture and hemorrhage. Acute occult blood loss and abdominal pain in probable cirrhotic suggests diagnosis. PMID- 4292446 TI - [Ovarian thecoma]. PMID- 4292447 TI - Degradation of oxytocin, lysine-vasopressin, angiotensin II and angiotensin-II amide by oxytocinase (cystine aminopeptidase). PMID- 4292448 TI - Transient QRS changes simulating myocardial infarction associated with shock and severe metabolic stress. PMID- 4292449 TI - Glomus tumors. Postauricular hypotympanotomy and hypotympanoplasty. PMID- 4292450 TI - Defective and delayed myxovirus infections. PMID- 4292451 TI - The virus of infectious bovine rhinotracheitis in Northern Nigeria. PMID- 4292453 TI - Photochemical formation of free radicals from aliphatic amines as studied by electron spin resonance. PMID- 4292452 TI - Hazards of drugs for rheumatoid arthritis. PMID- 4292454 TI - O-T-C depilatories. PMID- 4292455 TI - The use of corticosteroids and ACTH in allergic diseases. PMID- 4292457 TI - Effect of pyrophosphate on dissolution of hydroxyapatite and its possible importance in calcium homeostasis. PMID- 4292456 TI - Clostridium welchii bacteraemia: a case report with survival and review of the literature. PMID- 4292458 TI - Brain-dependent ACTH secretion from multiple heterotopic pituitaries. PMID- 4292459 TI - Characteristics of interferon induced in vitro and in vivo by a TRIC agent. PMID- 4292460 TI - Human adenoviruses: tumor production in hamsters by type 12 and 18 grown from single plaques. PMID- 4292461 TI - Studies on the mechanism of action of thymic leukemogenic virus. PMID- 4292463 TI - Challenge virus resistance and interferon produced in BS-C-1 cells by dengue virus. PMID- 4292462 TI - Antibody responses in acute and chronic rubella. PMID- 4292464 TI - Effects of hypophysectomy and growth hormone on renal compensatory hypertrophy in rats. PMID- 4292465 TI - ESR studies of model complexes for non-heme iron proteins. PMID- 4292468 TI - Gustatory sweating. PMID- 4292467 TI - Clinical syndromes associated with tumors of the pancreas. PMID- 4292466 TI - Cellular resistance to induction of interferon. PMID- 4292469 TI - Management of gestational trophoblastic disease. PMID- 4292470 TI - Reversible inactivation of angiotensin in hypertensive and normotensive subjects. PMID- 4292471 TI - Oxidation of testosterone acetate with per acids. PMID- 4292472 TI - [On the local use of a new antibiotic-corticoid combination in acute otitis]. PMID- 4292473 TI - Evaluation of the short child. PMID- 4292474 TI - Neoplasms of the placental trophoblast. PMID- 4292475 TI - Management of status asthmaticus. PMID- 4292476 TI - A new micro-neutralization test for antibody determination and typing of parainfluenza and influenza viruses. PMID- 4292477 TI - Exposure of Pseudomonas aeruginosa to hyperbaric oxygen: inhibited growth and enhanced activity of polymyxin B. PMID- 4292478 TI - Effects of cortisol and ACTH administration on some aspects of lipid metabolism in the hamster. PMID- 4292479 TI - A quantitative assay for avian myeloblastosis virus. PMID- 4292480 TI - Transformation of hamster embryo cells in vitro by Murine Sarcoma Virus (Harvey). PMID- 4292481 TI - Patterns of antibodies to SV40 in children following the last booster with inactivated poliomyelitis vaccines. PMID- 4292482 TI - Angiotensin blood levels in normal and toxemic pregnancies. PMID- 4292483 TI - Thin layer chromatography of toxicologically significant substances on silica gel coated glass plates and polyester sheets. PMID- 4292484 TI - [The activity of glucose-6-phosphatase following the administration of streptolycin in rats]. PMID- 4292485 TI - Metabolism of steroid hormones in adrenal cortex tumor cultures. PMID- 4292486 TI - Steroid synthesis in embryonic and fetal rat adrenal tissue. PMID- 4292487 TI - Effect of hypophysectomy and adrenalectomy on enzymes concerned with nicotinamide adenine dinucleotide synthesis. PMID- 4292488 TI - Melanocyte-stimulating hormone-releasing and inhibiting factors in two hypothalamic extracts. PMID- 4292489 TI - Pyrophosphate phosphohydrolase in mammary tissue of pregnant and lactating rats. PMID- 4292490 TI - Pituitary ACTH content in rats after partial or total interruption of neural afferents to the medial basal hypothalamus. PMID- 4292491 TI - Effect of administration of ACTH on insulin secretion in dogs. PMID- 4292492 TI - A new selective medium for Streptococcus pyogenes and other streptococci. PMID- 4292493 TI - Stability of antituberculosis drugs in Lowenstein-Jensen medium. PMID- 4292494 TI - Clinical Pathologic Conference No. 3. PMID- 4292495 TI - Electrodiagnosis. II. Peripheral nerve stimulation. PMID- 4292497 TI - [Generalized cytomegalic inclusion disease in infants]. PMID- 4292496 TI - [Surgically removed insuloma of atypical localization]. PMID- 4292498 TI - [Attempt to evaluate the effectiveness of rickets prevention in children in Zabrze]. PMID- 4292499 TI - [Cytometgaly complicated by septicemia in a newborn infant]. PMID- 4292500 TI - [Autopsy case of chronic Japanese encephalitis]. PMID- 4292501 TI - [Histopathological studies of "neurogenic dermatopathy of swine"]. PMID- 4292503 TI - Viruses and human cancer. PMID- 4292502 TI - [Adsorption anomalies in colloidal silicic acid towards invert soaps. 12. On the effect of auxiliary substances in the manufacturing of pharmaceutical preparations]. PMID- 4292504 TI - [Neuroblastoma with endocrine activity]. PMID- 4292506 TI - Clinicopathological conference 83 conducted by the Department of Pathology, University of Mississippi School of Medicine, Jackson, Mississippi. PMID- 4292505 TI - An investigation into thecomatosis of the ovary and related tumours by histochemical and enzyme histochemical methods. PMID- 4292507 TI - The isolation of viruses from acute respiratory infections. V. The use of organ cultures of human embryonic nasal and tracheal ciliated epithelium. PMID- 4292508 TI - Plasma 17-hydroxycorticosteroid levels following intra-cranial self-stimulation in rats. PMID- 4292509 TI - Canine herpesvirus infection of puppies. PMID- 4292510 TI - [The possibility of using ACTH in severe forms of multiple sclerosis]. PMID- 4292511 TI - Electron-spin resonance studies of photo-induced free radicals in native chloroplasts. PMID- 4292512 TI - [Pituitary functional reserve for ACTH excretion and the metyrapone test]. PMID- 4292513 TI - [Pituitary functional reserve for ACTH excretion in children after the administration of metyrapone]. PMID- 4292514 TI - [Pituitary functional reserve for ACTH excretion and the glycoregulatory and diuretic reflexes]. PMID- 4292516 TI - Ovarian neoplasms in childhood and adolescence. PMID- 4292515 TI - [Histochemical changes in the adrenals and in the spleen during the course of an active immunization and an anaphylactic shock in rabbits]. PMID- 4292517 TI - Nerve abscesses in Northern Nigeria. PMID- 4292518 TI - Acute appendicitis diagnosed as carcinoma of the stomach. PMID- 4292519 TI - [Clinical treatment of glandular malignant neoplasms of the upper alimentary tract and respiratory tracts with the exclusion of parotid gland tumors]. PMID- 4292520 TI - [CLlinical treatment of the mixed tumors of the head (except parotid gland)]. PMID- 4292522 TI - [Unusual case of chemodectoma located in the ear]. PMID- 4292521 TI - [Application of spodography in pathomorphology]. PMID- 4292523 TI - [Changes in body proportions of maturating boys in relation to their physiological age]. PMID- 4292524 TI - [Some physico-chemical aspects of inactivation of enteroviruses in an aqueous medium]. PMID- 4292525 TI - [Action of a chelating product (calcium disodium tetracemate) on the evolution of experimental infections with several viruses and on the development of some tumors]. PMID- 4292526 TI - [Association of serum hepatitis with cytomegalic inclusion disease in a premature infant from a twin pregnancy]. PMID- 4292527 TI - [Efficacy control of dried and glycerinated smallpox vaccines by challenging of successful primary vaccinations after one year with potent vaccine]. PMID- 4292528 TI - [Changes in some electrolytes, following blood withdrawal, from the aspect of the general adaptation syndrome]. PMID- 4292529 TI - [Current data on the determination of the length and age of human embryos according to the dimensions of the pelvic bones]. PMID- 4292531 TI - Histochemical comparison of dehydrogenases related to glucose metabolism in human tumors: localization and activity of lactate, glucose-6-phosphate, and 6 phosphogluconate dehydrogenases. PMID- 4292530 TI - Chemically characterized media for study of foot-and-mouth disease virus in baby hamster kidney cells. AB - Foot-and-mouth disease virus can be grown in baby hamster kidney cells with a chemically characterized medium containing only tris(hydroxymethyl)-amino-methane (Tris) buffer, glucose, glutamine, and salts. Virus infectivity was only 0.5 log unit less than in a complex cell growth medium containing serum, tryptose phosphate, and lactalbumin hydrolysate. At high multiplicity of infection, production was maximal in 5 hr, with the virus remaining largely intracellular. Glucose and glutamine appeared to act independently of each other although both were required at about the same time during the virus production cycle. Glutamine had the greater effect and could not be replaced by amino acids, purines, and pyrimidines. Glutamine also stimulated cellular oxygen uptake in both normal and infected cells. Serum and other organic components added singly to the defined medium did not increase the virus yield. Studies on uninfected cells over a 5-hr incubation period showed that the defined medium maintained protein and ribonucleic acid synthesis at rates similar to the complex cell growth medium. These rates were much lower in media containing only inorganic salts and Tris buffer. Glucose, however, was more important to uninfected cellular metabolism than was glutamine. Defined medium containing dialyzed calf serum produced the highest rate of protein synthesis. PMID- 4292532 TI - [Nobel Prize of the year. I. Peyton Rous]. PMID- 4292533 TI - Neoplastic transformation of rat embryo cells by simian papovavirus SV40. PMID- 4292535 TI - Recurrent herpes simplex ocular infection. PMID- 4292534 TI - Surgical management of benign intramural gastric tumors. PMID- 4292537 TI - [Leukemia-specific antigens in mice--its relation to viral antigens]. PMID- 4292536 TI - [Diagnosis and treatment of Hodgkinian adenopathies by radio-active lipiodol]. PMID- 4292538 TI - [Corticotropin-releasing factor (CRF)]. PMID- 4292539 TI - Jugularography as a diagnostic technique in otolaryngology. PMID- 4292541 TI - [Thevenard's acropathia ulcero-mutilans or Hicks-Denny Brown hereditary sensory radicular neuropathy]. PMID- 4292540 TI - Towards a rational chemotherapy of cancer. PMID- 4292542 TI - [Our experiences with Cytochrome-C-oxidase in the treatment of coronary disease]. PMID- 4292543 TI - [The significance of the Cytochrome-C enzyme therapy]. PMID- 4292544 TI - Children with steroid-dependent allergic asthma. PMID- 4292545 TI - [Isolation of mumps virus in tissue culture]. PMID- 4292547 TI - [Contribution to the treatment of congenital syndactyly]. PMID- 4292548 TI - [Surgical treatment of congenital syndactyly in children]. PMID- 4292546 TI - [Syndactyly of the hand according to our material]. PMID- 4292549 TI - [Surgical treatment of syndactyly of the hands]. PMID- 4292550 TI - [On the surgical treatment of congenital syndactyly]. PMID- 4292551 TI - [On the treatment of congenital hypotrophy of the thumb]. PMID- 4292552 TI - [Study of serum insulin-like activity by the rat epididymal fat pad method in obesity and diabetes]. PMID- 4292553 TI - Electron paramagnetic resonance studies of vitamin K and vitamin E quinones. PMID- 4292554 TI - The relationship between the virus of infectious canine hepatitis and inerstitial nephritis. PMID- 4292556 TI - [Studies on para-influenza virus type 3]. PMID- 4292555 TI - [The therapeutic prognosis in chronic evolutive polyarthritis (C.E.P.)]. PMID- 4292557 TI - [Infections with parainfluenza virus in children with acute inflammation of trachea and ear]. PMID- 4292558 TI - Trophoblastic malignancies. PMID- 4292559 TI - [Application of synthetic ACTH for evaluation of the functional reserve of the adrenal cortex]. PMID- 4292560 TI - [Role of the renin-angiotensin system in sodium metabolism]. PMID- 4292561 TI - [Tarsal tunnel syndrome]. PMID- 4292562 TI - [Influence of corticostimulin on the reactivity of the genital system and on the evolution of the sexual cycle]. PMID- 4292563 TI - [Bronchial adenomas]. PMID- 4292564 TI - [A case of generalized scleroderma and alveolar cell carcinoma]. PMID- 4292565 TI - Corticosteroids and corticotropins in dermatological practice. PMID- 4292566 TI - Three outbreaks of foodborne disease with dual etiology. PMID- 4292568 TI - Primary scirrhous carcinoma of colon. Roentgenologic diagnosis. PMID- 4292569 TI - Carcinosarcoma of the esophagus. PMID- 4292567 TI - Biosynthesis of starch in chloroplasts. AB - The enzymic synthesis of ADP-glucose and UDP-glucose by chloroplastic pyrophosphorylase of bean and rice leaves has been demonstrated by paper chromatographic techniques. In both tissues, the activity of UDP-glucose pyrophosphorylase was much higher than ADP-glucose-pyrophosphorylase. Glycerate-3 phosphate, phosphoenolpyruvate and fructose-1,6-diphosphate did not stimulate ADP glucose formation by a pyrophosphorylation reaction. The major metabolic pathway for UDP-glucose utilization appears to be the synthesis of either sucrose or sucrose-P. On the other hand, a specific precursor role of ADP-glucose for synthesizing chloroplast starch by the ADP-glucose-starch transglucosylase reaction is supported by the coupled enzyme system of ADP-glucose pyrophosphorylase and transglucosylase, isolated from chloroplasts. None of the glycolytic intermediates stimulated the glucose transfer in the enzyme sequence of reaction system employed. PMID- 4292570 TI - Correlations in the partition thin-layer chromatography of alkali metals. PMID- 4292571 TI - [Application of the ion exchange properties of silica gel to the separation of metals]. PMID- 4292573 TI - Recurrent cystosarcoma phylloides. PMID- 4292574 TI - Adrenocorticotropins. 37. The synthesis of lysine 8-alpha-1-17NH 2-ACTH and its biological properties. PMID- 4292572 TI - Intracellular collagen fibers. In human mesenchymal tumors and inflammatory states. PMID- 4292575 TI - Synthesis of human angiotensin I. PMID- 4292576 TI - Photochemical formation of free radicals from hydrogen sulfide, mercaptans, and cysteine. PMID- 4292577 TI - The kinetics of the periodate oxidation of substituted 2-aminoethanols. PMID- 4292578 TI - Intra-oral presentation of lateral pharyngeal space tumors. PMID- 4292580 TI - [Biosynthesis of NAD(DPN) in the brain and its metabolic turnover]. PMID- 4292579 TI - [Nodular hydroadenoma (type sudoriparous myoepithelioma)]. PMID- 4292581 TI - [Characteristics of NAD metabolism in the brain--with reference to a comparison with the liver]. PMID- 4292582 TI - [The autonomic nervous system and carbohydrate metabolism in the liver]. PMID- 4292583 TI - Clinical study on primary carcinoma of the liver in Taiwan. PMID- 4292586 TI - Bisulphite addition compounds of periodate-oxidised polysaccharides: electrophoretic mobility, and precipitation by cetylpyridinium and other organic cations. PMID- 4292585 TI - Current management glomus jugulare tumors. PMID- 4292584 TI - Intraosseous glomus tumor. A case report. PMID- 4292587 TI - [Neurologic disturbances in pregnant women]. PMID- 4292588 TI - Studies on the relationship of the thermosensibility and sensibility to the acidic pH of certain cliones of foot and mouth disease virus obtained at infra optimal temperature of 29 degrees C. PMID- 4292590 TI - The overoxidation of carbohydrates with sodium metaperiodate. PMID- 4292589 TI - Further studies of phosphatases in tissues and serum using gel-filtration techniques. PMID- 4292591 TI - Cryotherapy in otorhinolaryngology. PMID- 4292592 TI - [Our experiences with hazards and side effects caused by intralymphatic injection of superfluid iodized oil, based on 86 cases]. PMID- 4292593 TI - [Indexes of hepatic clearance in rachitic children]. PMID- 4292594 TI - [Bronchial adenomas]. PMID- 4292595 TI - The present position of the treatment of parotid tumours. PMID- 4292596 TI - [Intrapulmonary localization of histiocytoma]. PMID- 4292597 TI - The induction of cancer by viruses. PMID- 4292598 TI - Free radicals derived from phenothiazine. PMID- 4292599 TI - P1, P2-pyrophosphates as initiators in the terminal deoxyribonucleotide transferase reaction. LA-3610-MS. PMID- 4292600 TI - [Determination of the size of embryos from the dimension of the radius]. PMID- 4292601 TI - [On the histotopography of adenosine triphosphatase in bovine endometrium during the late follicular phase]. PMID- 4292603 TI - [Paraneoplastic neuropathies]. PMID- 4292602 TI - Fine structural alterations of Yoshida ascites hepatoma cells following treatment with L-erythro-alpha, beta-dihydroxybutyraldehyde. PMID- 4292604 TI - Administration of corticotropin beta-1-24 as a rapid test of adrenal cortical function. PMID- 4292605 TI - Hepatoma. A clinical and pathologic study of cases occurring during 1950-1959 in Hawaii. PMID- 4292606 TI - Fine structural localization of acid and alkaline phosphatases in cells of rabbit blood and bone marrow. PMID- 4292607 TI - Clostridium perfringens septicemia as a postoperative complication of the newborn infant. PMID- 4292608 TI - [Skeletal build and body weight. A statisticsomatometric study in 8-25-year-old boys and men]. PMID- 4292610 TI - [Clinical and surgical considerations on mixed tumors]. PMID- 4292609 TI - [Clinical and therapeutic considerations on nasopharyngeal fibroma in children]. PMID- 4292611 TI - [Epidemic due to respiratory syncytial virus in a children's community]. PMID- 4292612 TI - [Modification of foot-and-mouth disease virus by passage in tissue culture; relationship between virulence for mice and rat characteristics]. PMID- 4292613 TI - [Thermostable inhibitors against foot-and-mouth disease virus in pig serum. 3. Electrophoretic and chromatographic studies]. PMID- 4292614 TI - [Determining the keeping quality of concentrated foot-and-mouth disease vaccine by measurement of PD 50 in cattle]. PMID- 4292615 TI - [A case of nonchromaffin paraganglioma originating in the suprasellar region and invading the nose through the sphenoid sinus]. PMID- 4292616 TI - [The auriculotemporal syndrome]. PMID- 4292617 TI - Factors affecting filtration rates of flocculaed silica. PMID- 4292618 TI - Vitamin D3--biologically active metabolites. PMID- 4292619 TI - [Reciprocal effect of diffuse scleroderma and pregnancy]. PMID- 4292620 TI - [Attempted dynamic evaluation of skeletal calcification in the course of therapy of calssical rickets in infants]. PMID- 4292621 TI - [Leurosine, the 3d alkaloid from Vinca rosea, in the treatmen t of Hodgkin's disease, acute lymphoblastic leukemia and lymphoblastosarcoma]. PMID- 4292623 TI - [Treatment of acute lymphoblastic leukemia during a remission by irradiation of the central nervous system and subsequent administration of 8 chemotherapeutic agents]. PMID- 4292622 TI - [The treatment of acute leukemias with methyl-glyoxal-bis (guanylhydrazone) and its combination with 2-hydroxystilbamidine]. PMID- 4292624 TI - [Trial treatment of chronic myeloid leukemia with 3 new chemotherapeutic agents: dibromomannitol, hydroxyurea and desacetamidocolchicine]. PMID- 4292625 TI - [Trial treatment of generalized Hodgkin's disease by multiple chemotherapy]. PMID- 4292626 TI - [Occupational pneumoconiosis contracted in a limekiln]. PMID- 4292627 TI - [Critical study of prothrombin levels]. PMID- 4292628 TI - [A case of cancer of the gastric stump after surgery for ulcer]. PMID- 4292629 TI - Studies in hypoglycemia of infancy and childhood. Diagnosis and treatment. PMID- 4292630 TI - [Renin and angiotensinase activity in renal venous blood following angiotensin administration]. PMID- 4292631 TI - Sodium-potassium ratio in the urine after ACTH stimulation. A simple test of adrenocortical function. PMID- 4292632 TI - Nonempirical calculations of the isotropic hyperfine splitting constants of 13-C, 14-N, and 17-O in simple radicals. PMID- 4292633 TI - [Effect of irradiation on the uptake of P32 by ascites and solid tumour cells and by their cellular components]. PMID- 4292634 TI - [Naeviform syndrome with skin atrophies]. PMID- 4292635 TI - Chemodectomas of the head and neck. PMID- 4292636 TI - Paraplegia in childhood malignant disease. PMID- 4292637 TI - Use of reagent-impregnated ("Patho-Tec") test papers in the identification of Enterobacteriaceae and similar bacteria. PMID- 4292638 TI - Nature of the pressor substance in rabbit placenta. AB - 1. The renin-like substance isolated from the placenta of the rabbit produces a prolonged increase of blood pressure in the nephrectomized rat. If incubated with renin substrate from ox serum, it forms a pressor substance that elevates blood pressure in exactly the same way as does angiotensin. 2. This angiotensin-like principle was concentrated by means of ion-exchange chromatography and compared with Val-5-angiotensins I and II in two paper-chromatography systems and in paper electrophoresis. 3. In all the three methods the unknown principle behaved like a mixture of the two reference compounds. 4. It is concluded that incubation of the renin-like substance of placental origin with substrate from ox serum gave a mixture of Val-5-angiotensins I and II. This is evidence that the enzyme isolated from the placenta is either closely related to, or identical with, renin. PMID- 4292639 TI - Biochemical properties of anti-inflammatory drugs. VII. Inhibition of proteolytic enzymes in connective tissue by chloroquine (resochin) and related antimalarial antirheumatic drugs. PMID- 4292640 TI - Some properties of the products of reaction of tadpole collagenase with collagen. PMID- 4292642 TI - Biosynthesis of procollagen in rabbit sponge capsular tissue. PMID- 4292641 TI - Incorporation of labeled precursors into lipids of tumors induced by Rous carcoma virus. PMID- 4292643 TI - Interaction of Neurospora mitochondrial structural protein with other proteins and coenzyme nucleotides. PMID- 4292644 TI - Zone electrophoresis of the proteins of avian myeloblastosis virus. PMID- 4292645 TI - [Corneal abscesses caused by Pseudomonas]. PMID- 4292647 TI - [The insecticidal effect of highly dispersed silicic acid on ectoparasites of poultry]. PMID- 4292646 TI - African swine fever. I. Antiserum production. AB - These studies report on the production of African swine fever antiserum for use in serological tests. The first attempt to obtain antiserum was made by inoculating ASF virus - infected pig blood into the lactiferous sinus of lactating bovines. This failed to result in the development of detectable antibody, but resulted in propagation of the virus over a 14 to 21 day period. In the second attempt use was made of a tissue culture - attenuated virus to produce resistance in normal pigs. Clinical response to inoculation with the attenuated virus was limited to a one day increase of temperature. These pigs were subsequently orally exposed to virulent ASF virus and later challenged by intramuscular injection. The sera were subjected to testing by the modified direct complement-fixation test and the agar gel double-diffusion technique in order to follow the development of antibodies. Some sera were also conjugated with fluorescein isothiocyanate and used for the detection of viral antigen by the fluorescent antibody technique. It was found that inoculation with the attenuated virus brought about the development of low antibody levels in the pigs. This antibody level did not increase following oral exposure. One pig following intramuscular challenge underwent a series of ascending temperature peaks, coinciding with increased complement-fixing titres. PMID- 4292648 TI - [Experimental studies on the calciphylaxy phenomenon in HeLa cell culture]. PMID- 4292649 TI - Induction of tumours in mice with three variants of rous sarcoma virus and studies on the immunobiology of these tumours. PMID- 4292650 TI - Characteristics of highly polyploid clones isolated from lines of RSV-transformed rat cells. PMID- 4292651 TI - Isolation and basic characteristics of template active RNA of BAI strain A virus (avian myeloblastosis). PMID- 4292653 TI - Sarcomas in reptiles induced with Rous virus. PMID- 4292652 TI - Adaptation of L cells and of lines of virogenic rat cells transformed by Rous sarcoma virus to growth in protein-free synthetic medium. PMID- 4292654 TI - [Clinical studies on the plasma corticosterone in man. 3. Clinical studies on plasma corticosterone in essential hypertension]. PMID- 4292655 TI - Electron microscopy of size and shape of viral DNA in solutions of different ionic strengths. PMID- 4292656 TI - [The clinical aspects of beta-cell tumors of the islands of Langerhans]. PMID- 4292657 TI - Joint statement on cardiopulmonary resuscitation issued by Minnesota Nurses Association, Minnesota State Medical Association and Minnesota Hospital Association. PMID- 4292658 TI - State junior colleges and the preparation of nurses. PMID- 4292659 TI - Joint statement on I.V. administration of fluids issued by Minnesota Nurses Association, Minnesota State Medical Association, and Minnesota Hospital Association. PMID- 4292660 TI - Zyloprim and other drugs in the management of gout. PMID- 4292661 TI - Atypical reaction to inhaled silica. PMID- 4292663 TI - [Glomus tumors]. PMID- 4292662 TI - Possible synergic influence of ACTH and FSH on the adrenal cortex in hypophysectomized-gonadectomized rats. PMID- 4292664 TI - The binding sites of iron in rubredoxin from Micrococcus aerogenes. PMID- 4292665 TI - Mapping the 5'-terminal nucleotides of the DNA of bacteriophage lambda and related phages. PMID- 4292666 TI - Specific activation of the DNA-synthesizing apparatus in contact-inhibited mouse kidney cells by polyoma virus. PMID- 4292668 TI - [Result of treatment of 54 ovarian tumors producing follicle stimulating hormone with an observation period of 5-18 years]. PMID- 4292667 TI - Stimulating interaction between viruses (stimulons). PMID- 4292669 TI - [On the causative agent of herpes zoster]. PMID- 4292670 TI - [The use of desoxyribonuclease in the therapy of adenovirus epidemic keratoconjunctivitis]. PMID- 4292671 TI - Experimental virus pneumonia in lambs. PMID- 4292672 TI - [Isolation of vesicular stomatitis virus from a patient]. PMID- 4292673 TI - Comprehensive treatment of acute hemorrhagic pancreatitis. PMID- 4292674 TI - The effects of ionizing radiation on nucleic acids of bacteriophages and bacterial cells. PMID- 4292675 TI - Virus leukemia in the mouse. PMID- 4292676 TI - Neurologic manifestations of Hodgkin's disease. Intracerebral Hodgkin's granuloma. PMID- 4292677 TI - Blind pancreatic resection for suspected insulinoma: a review of the problem. PMID- 4292678 TI - Glomus jugulare tumours with special reference to their radiological features. PMID- 4292680 TI - Postoperative gas gangrene. PMID- 4292679 TI - Chemodectoma in the region of the aortic bifurcation. PMID- 4292681 TI - Beta-hydroxybutyrate dehydrogenase activity in liver and liver tumors. PMID- 4292682 TI - The in vitro soluble RNA methylase activity of SV40-induced hamster tumors. PMID- 4292683 TI - The neonatal and infant age periods as biologic factors which modify multicarcinogenesis by urethan. PMID- 4292684 TI - Stimulation of DNA synthesis and thymidine kinase activity in human embryonic kidney cells infected by Adenovirus 2 or 12. PMID- 4292685 TI - Amino acids of the ornithine cycle in transformed hamster fibroblasts carrying pleuropneumonia-like organisms. PMID- 4292686 TI - Variola minor. Observations and experiences in Staffordshire, England, during 1966. PMID- 4292687 TI - Post-hospital contacts with schizophrenics. PMID- 4292688 TI - [Typical primary synovial sarcoma of the orbit]. PMID- 4292689 TI - Portal hypertension: current status of surgical management. PMID- 4292690 TI - Effects of angiotensin and renal artery constriction on erythropoietin production. PMID- 4292691 TI - Cylindroma (adenoid cystic carcinoma) of the upper air passages. Two case reports. PMID- 4292692 TI - Cutaneous flushing as a primary manifestation of functioning insulinoma: report of a case. PMID- 4292693 TI - Thyroid stimulating and pigmentary effects of synthetic peptides related to alpha MSH and ACTH. PMID- 4292694 TI - The dimple sign in peroneal palsy. PMID- 4292695 TI - Human collagenase: identification and characterization of an enzyme from rheumatoid synovium in culture. AB - Synovial tissue from patients with rheumatoid arthritis produces lysis of gels of reconstituted collagen fibrils in culture and releases soluble collagenase when cultured in collagen-free medium. Collagen molecules in solution at neutral pH at 20 degrees and 27 degrees C are cleaved by the synovial enzyme into (3/4) and (1/4) length fragments. In this respect the action of synovial enzyme is similar to that of amphibian collagenase and distinct from that of bacterial collagenase. At 37 degrees C reconstituted collagen fibrils and native fibers are attacked by the enzyme and further degraded to polypeptides of low molecular weight. These polypeptides are produced only after denaturation of the larger fragments, which occurs at temperatures near 37 degrees C. PMID- 4292696 TI - Management of trophoblastic disease at the University Hospital. PMID- 4292697 TI - Medical grand rounds from the University of Alabama Medical Center. PMID- 4292698 TI - Parabiotic dialysis. PMID- 4292699 TI - Uremic polyneuropathy: and motor nerve conduction velocities. PMID- 4292700 TI - Enzyme histochemistry of the angle of the anterior chamber of the human eye. PMID- 4292701 TI - A method for sequential quantitative separation and determination of protein, RNA, DNA, lipid, and glycogen from a single rat liver homogenate or from a subcellular fraction. PMID- 4292702 TI - Use of a sensitive new method for determination of the urinary excretion of dichlorodiphenylacetic acid (DDA) by human subjects. PMID- 4292703 TI - Determination of phosphate in biological materials and reaction mixtures by atomic absorption spectrophotometry. PMID- 4292704 TI - A gas chromatographic method for analysis of anomeric carbohydrates and for determination of mutarotation coefficients. PMID- 4292705 TI - Determination of intracellular 2-deoxy-D-glucose 6-phosphate and uridine diphosphate-2-deoxy-D-glucose. PMID- 4292706 TI - Detection and differentiation of sugars on paper by the p-anisidine-periodate reaction. PMID- 4292708 TI - [Sensitivity of monkey kidney cells to viruses before and after freezing]. PMID- 4292707 TI - Microenzymic method for the quantitative analysis of acetyl groups in proteins and peptides. PMID- 4292709 TI - [Development of the cytomegalic virus on newborn mouse salivary gland explant]. PMID- 4292711 TI - Effect of isoniazid on preservation of nicotinamide dinucleotide in animal cells. PMID- 4292710 TI - Electron transport systems of yeast. IV. Preparation and properties of a particulate DPNH, succinate cytochrome c reductase. PMID- 4292713 TI - Enzymic polymerization of monosaccharides. I. The enzymic polymerization of D galactose. PMID- 4292712 TI - Effect of N1-alkylnicotinamide chlorides on glutamate oxidation in rat liver mitochondria. PMID- 4292714 TI - Enzymic polymerization of monosaccharides. II. Synthesis of 2-acetamido-2-deoxy-6 O-(alpha-D-galactopyranosyl)-D-glucose (N-acetylmelibiosamine). PMID- 4292715 TI - Demonstration of the Schiff base mechanism in an aldolase reaction by oxygen exchange. PMID- 4292716 TI - Optical activity of hematin A. PMID- 4292717 TI - A purified plasma membrane fraction isolated from rat liver under isotonic conditions. PMID- 4292718 TI - Techniques for analysis of glucose binding by human erythrocyte membranes. PMID- 4292719 TI - Studies on the mechanism of cyclization of glucose 6-phosphate to D-inositol 1 phosphate. PMID- 4292720 TI - Biosynthesis of nicotinamide-adenine dinucleotide in Escherichia coli. PMID- 4292722 TI - Stability of nucleolar 45-S RNA. PMID- 4292721 TI - On the mode of action of 7-deaza-adenosine (tubercidin). PMID- 4292723 TI - Magnetic susceptibility measurements on hemoproteins down to 4.2 degrees K. PMID- 4292724 TI - [Formation and structure of the ascorbate radical]. PMID- 4292725 TI - 2,3-Dihydroxybenzoate as a bacterial growth factor and its route of biosynthesis. PMID- 4292726 TI - Polyanions and their complexes. II. Light-induced paramagnetism in solid glycosaminoglycan-dye complexes. PMID- 4292727 TI - [Lack of interference of guanidine and D-penicillamine in the capacity of poliovirus to disaggregate polysomes]. PMID- 4292728 TI - [Seminal phosphodiesterase]. PMID- 4292729 TI - Controlled evaluation of nicotinamide adenine dinucleotide in the treatment of chronic schizophrenic patients. PMID- 4292731 TI - [Sarcoid and tuberculoid type of skin granuloma after interacutaneous injection of sterile aqueous solutions of local anesthetics]. PMID- 4292730 TI - Effects of intravenous administration of adrenocorticotrophin on the adrenal lipids of the rabbit. PMID- 4292732 TI - Acute ascending polyradiculomyelitis. Associated with ECHO 9 virus. PMID- 4292733 TI - Spores of microorganisms. XXI. Conversion of outgrowing spores of Bacillus cereus to refractile forms by basic peptides and proteins. PMID- 4292735 TI - Nucleic acids. I. The synthesis of nucleotides and dinucleoside phosphates containing ara-cytidine. PMID- 4292734 TI - The structure-activity relationship in barbiturates and its similarity to that in other narcotics. PMID- 4292736 TI - Nucleic acids. 3. Antiviral activity of nucleotides and dinucleoside phosphates containing ara-cytidine. PMID- 4292737 TI - Synthesis and antiviral and antibacterial activity of certain N dialkylaminomethylisatin beta-thiosemicarbazones. PMID- 4292738 TI - Changes of mitochondrial RNA level during the transition from rest to growth in the endosperm of germinating castor beans. PMID- 4292740 TI - Histogenesis of the granular-cell myoblastoma. PMID- 4292741 TI - Incidence of cytomegalic infection in man. PMID- 4292739 TI - Pathways of glucose utilization in kidney homogenates of tuberculous and isoniazid-treated tuberculous guinea pigs. (Preliminary report). PMID- 4292742 TI - [Essential pes cavus]. PMID- 4292744 TI - [The treatment of serofibrinous pleurisy with corticoid therapy, exclusively local, after routine evacuative puncture and associated antibiotics]. PMID- 4292743 TI - [Selective capillary angiography in pneumology]. PMID- 4292745 TI - [The bronchospasmodic factor in asthma and chronic bronchitis. Demonstration by study of ventilatory mechanics]. PMID- 4292746 TI - [Subcutaneous heparin therapy]. PMID- 4292747 TI - [Extenuation of the effect of oral treatment in diabetics]. PMID- 4292748 TI - [Influence of dihydroergotamine on certain hepatic functions in man]. PMID- 4292749 TI - [Apropos of false cysts of the pancreas]. PMID- 4292750 TI - "Early, non-virion" antigens in herpes simplex virus infected tissue culture cells. I. Detection of "early" antigens with complement fixation test. PMID- 4292751 TI - The implication of acid concentration in lipid phosphorus determinations. PMID- 4292752 TI - Detection and determination of 4-hydroxyskatole sulfate ester. PMID- 4292754 TI - Spontaneous and detergent activation of a glucuronyltransferase in vitro. PMID- 4292753 TI - A direct spectrophotometric assay for pyruvate kinase. PMID- 4292756 TI - Incorporation of 2-deoxyglucose into glycogen by intact Novikoff ascites hepatoma. PMID- 4292755 TI - A comparative study of glycogen and lactate formation from glucose, glucose 6 phosphate, alpha-glucose 1-phosphate, and uridine diphosphate glucose by intact Novikoff ascites-hepatoma cells. PMID- 4292757 TI - Simultaneous binding of coenzyme-competitive inhibitors of yeast alcohol dehydrogenase. PMID- 4292758 TI - Specific cleavage of tryptophyl peptide bonds with periodate in sperm whale myoglobin. PMID- 4292759 TI - Ion accumulation in bacterial systems. I. Isolation of two particulate fractions participating in silicon metabolism, from Proteus mirabilis cell-free extracts. PMID- 4292760 TI - Ion accumulation in bacterial systems. II. Properties of silicate-metabolizing cell-free extracts and particulate fractions from Proteus mirabilis. PMID- 4292761 TI - On the potentiation of kinins by sulfhydrylic compounds. PMID- 4292762 TI - Further studies on noradrenaline postinfusional hypotension. PMID- 4292763 TI - The investigation of hypopituitarism. PMID- 4292764 TI - An evaluation of screening procedures in the diagnosis of reno-vascular hypertension. PMID- 4292765 TI - The response of the blood pressure to an infusion of angiotensin in patients with essential malignant and renovascular hypertension. PMID- 4292766 TI - The action of trypsin and of chymotrypsin on phenylthiocarbamyl-angiotensin II. PMID- 4292767 TI - Effects of serum proteins in vitro on the synthesis of rapidly labelled ribonucleic acid and on the polysome pattern of yoshida ascites-hepatoma cells. PMID- 4292768 TI - A method for the study of bone mucosubstances by using collagenase. PMID- 4292769 TI - Conversion of reduced nicotinamide-adenine dinucleotide dehydrogenase into reduced nicotinamide-adenine dinucleotide-ubiquinone reductase. PMID- 4292770 TI - Isopentyl pyrophosphate isomerase from pig liver. PMID- 4292771 TI - Polyoma-virus-induced deoxyribonucleic acid polymerase activity in resting mouse embryo cells. PMID- 4292773 TI - The inhibition of skeletal-muscle fructose 1,6-diphosphatase by adenosine monophosphate. AB - 1. The present study extends the finding of Krebs & Woodford (1965) that muscle fructose diphosphatase is more sensitive to AMP inhibition than liver fructose diphosphatase. 2. Hen breast fructose diphosphatase has a K(i) for AMP of 0.1mum; the plot of percentage inhibition is non-sigmoid and the reciprocal plot of activity against AMP concentration is sometimes linear. 3. Percentage inhibition plots for other muscle fructose diphosphatases are sigmoid curves which exhibit different threshold responses to the AMP concentration. 4. The intracellular content of AMP in all muscles tested exceeds the inhibition concentration range of AMP. 5. The sensitivity of muscle fructose diphosphatase to AMP inhibition is decreased by the presence of Mg(2+) or Mn(2+) ions; in the presence of Mn(2+) the inhibition curve for hen breast fructose diphosphatase becomes sigmoid. 6. From the formation constants for the Mg(2+) and Mn(2+) chelates, the effect of these ions in chelation of AMP can be calculated. Although chelation of AMP can explain the Mg(2+) effect, it cannot explain the marked relief of AMP inhibition by Mn(2+). 7. It is suggested that Mn(2+) has a specific effect on this enzyme which reduces the sensitivity to AMP inhibition. PMID- 4292774 TI - A comparison of the properties of fructose 1,6-diphosphatase, and the activities of other key enzymes of carbohydrate metabolism, in the livers of embryonic and adult rat, sheep and domestic fowl. AB - 1. The activities of some key enzymes of glycolysis and gluconeogenesis were measured in embryonic chick, sheep and rat livers. 2. In chicken the activities of hexokinase, phosphofructokinase and pyruvate kinase are low, but those of glucose 6-phosphatase and fructose diphosphatase are very high; the converse situation exists in the rat (Burch et al. 1963), but in sheep the activities of both phosphofructokinase and fructose diphosphatase are high, and the activities of hexokinase and glucose 6-phosphatase are low. These findings are discussed in relation to carbohydrate metabolism in these embryonic livers. 3. The regulatory properties of fructose diphosphatase from the embryonic livers of these three species were compared with the properties of the enzymes from adult animals. The inhibitions by AMP and fructose diphosphate and the effects of Mg(2+) and pH on the activities of adult and foetal fructose diphosphatase are almost identical. 4. It is concluded that regulatory properties are characteristic of fructose diphosphatase from embryonic and adult tissue, and the importance of this in relation to enzyme development is discussed. PMID- 4292772 TI - Oxidative phosphorylation and respiratory control in mitochondria from Aspergillus niger. AB - 1. Tightly coupled mitochondria were isolated from Aspergillus niger by using an all-glass homogenizer followed by differential centrifugation. 2. The mitochondria oxidized the common intermediates of the tricarboxylic acid cycle, NADH(2) and the ascorbate-tetramethyl-p-phenylenediamine system. 3. High P/O ratios and control of respiration by ADP were obtained with all substrates tested. The average P/O ratios observed were: 1.5-1.8 with succinate as substrate [respiratory control ratio (RC) 2-4]; 0.8-1.0 with ascorbate-tetramethyl-p phenylenediamine (RC 1.2-1.5); 1.4-1.8 with NADH(2) (RC 2-3); 2.4-2.8 with alpha oxoglutarate (RC 3-5). 4. Bovine serum albumin (0.05-0.2%) was essential for tightly coupled respiration to be observed. 5. Coupled oxidation of exogenous NADH(2) was relatively insensitive to rotenone and Amytal. 6. The mitochondria responded to specific inhibitors and uncoupling agents in a manner similar to that of mammalian mitochondria. 7. It was concluded that the isolated mitochondria from A. niger show respiratory properties similar to those reported for intact yeast and mammalian mitochondria. PMID- 4292776 TI - [Methylation of dinucleoside phosphates with diazomethane]. PMID- 4292775 TI - Altered specificity of transfer-ribonucleic acid nucleotidyltransferase in the presence of manganese. AB - 1. s-RNA nucleotidyltransferase incorporated CMP into phosphodiesterase-treated s RNA more rapidly in the presence of Mg(2+) (10mm) than in the presence of Mn(2+) (2mm). UMP was incorporated more rapidly in the presence of Mn(2+), and at high ionic strength the incorporation of CMP was also more rapid in the presence of Mn(2+). 2. The capacity of phosphodiesterase-treated s-RNA for CMP, UMP and AMP was increased in the presence of Mn(2+). Terminal sequences of more than one UMP or AMP residue were synthesized, but these atypical reactions were inhibited when CTP was added. CMP was incorporated rapidly to form -pCpC terminal sequences and then more slowly as longer chains were formed, but very little CMP was incorporated into s-RNA-pCpCpA. 3. CMP was incorporated into phosphodiesterase treated 5s RNA and ribosomal RNA to form short chains of polyC attached to the primer RNA. This reaction was inhibited by the presence of s-RNA. 4. A small Mn(2+)-dependent incorporation of CMP was also primed by poly(A).(U) and poly(C).(I). PMID- 4292777 TI - Polyribosome breakdown in rat liver following administration of 8-azaguanine. PMID- 4292778 TI - Polyribosomes in normal Krebs 2 ascites tumor cells and in cells infected with encephalomyocarditis virus. PMID- 4292779 TI - Polymerization of the adenosine 5'-diphosphate ribose moiety of NAD by rat liver nuclear enzyme. PMID- 4292780 TI - Fractionation of nuclear ribonucleic acids from tumor and homologous tissue on a methylated albumin column by the use of salt and temperature gradients. PMID- 4292781 TI - Action of cyclic phosphodiesterase from Escherichia coli on tobacco mosaic virus ribonucleic acid. PMID- 4292782 TI - The action of snake venom phosphodiesterase on liver ribosomal ribonucleic acids. PMID- 4292783 TI - An extension of the naphthalene disulphonate method for mammalian nucleic acids. PMID- 4292785 TI - Phosphate metabolism in the electric organ. PMID- 4292784 TI - Relationship between photosynthetic and oxidative phosphorylations in chromatophores from light-grown cells of Rhodospirillum rubrum. PMID- 4292786 TI - Inhibitors of NADH-ubiquinone reductase from mitochondria. PMID- 4292787 TI - Cytochrome oxidase and its derivatives. VII. Further observations on the compound formed by the reaction of ferrous cytochrome c oxidase with oxygen and hydrogen peroxide and on its reactions. PMID- 4292788 TI - The low-temperature spectral properties of mammalian cytochrome oxidase. I. The enzyme in intact rat-liver mitochondria. PMID- 4292789 TI - The occurrence of cytochromes in nuclei isolated from rat thymus. PMID- 4292790 TI - Comparative phosphorescence quenching of DNA's of different composition. AB - Small amounts of paramagnetic cations quench the phosphorescence of DNA. Although the emission intensity is monotonic with increasing thymine content, the quenching efficiency is not. The cations quench from phosphate sites. PMID- 4292791 TI - Neuronal spike trains and stochastic point processes. I. The single spike train. AB - In a growing class of neurophysiological experiments, the train of impulses ("spikes") produced by a nerve cell is subjected to statistical treatment involving the time intervals between spikes. The statistical techniques available for the analysis of single spike trains are described and related to the underlying mathematical theory, that of stochastic point processes, i.e., of stochastic processes whose realizations may be described as series of point events occurring in time, separated by random intervals. For single stationary spike trains, several orders of complexity of statistical treatment are described; the major distinction is that between statistical measures that depend in an essential way on the serial order of interspike intervals and those that are order-independent. The interrelations among the several types of calculations are shown, and an attempt is made to ameliorate the current nomenclatural confusion in this field. Applications, interpretations, and potential difficulties of the statistical techniques are discussed, with special reference to types of spike trains encountered experimentally. Next, the related types of analysis are described for experiments which involve repeated presentations of a brief, isolated stimulus. Finally, the effects of nonstationarity, e.g. long-term changes in firing rate, on the various statistical measures are discussed. Several commonly observed patterns of spike activity are shown to be differentially sensitive to such changes. A companion paper covers the analysis of simultaneously observed spike trains. PMID- 4292792 TI - Neuronal spike trains and stochastic point processes. II. Simultaneous spike trains. AB - The statistical analysis of two simultaneously observed trains of neuronal spikes is described, using as a conceptual framework the theory of stochastic point processes.The first statistical question that arises is whether the observed trains are independent; statistical techniques for testing independence are developed around the notion that, under the null hypothesis, the times of spike occurrence in one train represent random instants in time with respect to the other. If the null hypothesis is rejected-if dependence is attributed to the trains-the problem then becomes that of characterizing the nature and source of the observed dependencies. Statistical signs of various classes of dependencies, including direct interaction and shared input, are discussed and illustrated through computer simulations of interacting neurons. The effects of nonstationarities on the statistical measures for simultaneous spike trains are also discussed. For two-train comparisons of irregularly discharging nerve cells, moderate nonstationarities are shown to have little effect on the detection of interactions.Combining repetitive stimulation and simultaneous recording of spike trains from two (or more) neurons yields additional clues as to possible modes of interaction among the monitored neurons; the theory presented is illustrated by an application to experimentally obtained data from auditory neurons.A companion paper covers the analysis of single spike trains. PMID- 4292793 TI - [Immunofluorescent development of the tumor antigen induced by the polyoma virus in strain BHK-21]. PMID- 4292794 TI - [Induction of hepatomas by means of natural radioactivity in mice. Preliminary results of an experimental histological and ultrastructural study]. PMID- 4292795 TI - Hypophosphatasia in an adult. A case report. PMID- 4292796 TI - Abortion in cattle caused by experimental infection with infectious bovine rhinotracheitis virus. PMID- 4292797 TI - Ribonuclease-cyclic phosphodiesterase system in Escherichia coli. PMID- 4292798 TI - Effects of bretylium, guanethidine and bethanidine on the cat's pad sweat glands. PMID- 4292799 TI - The effects of angiotensin on the concentration of plasma free fatty acids in man. PMID- 4292800 TI - Some vascular effects of angiotensin in the rat. PMID- 4292801 TI - Chemical fractionation of antiviral plants. PMID- 4292802 TI - Association of glycine with spinal interneurones. PMID- 4292803 TI - Inhibition of motoneurones by iontophoresis of glycine. PMID- 4292804 TI - Buoyant density of herpes simplex virus in solutions of caesium chloride. PMID- 4292805 TI - Polycation effect on virulence of nonpathogenic r+ variant of the encephalomyocarditis virus. PMID- 4292806 TI - Reciprocal interference between mouse mammary tumour virus and leukaemia virus. PMID- 4292807 TI - Disappearance of angiotensin from the circulation of the dog. PMID- 4292808 TI - Effect of rotenone on the alcohol dehydrogenase of yeast mitochondria. PMID- 4292809 TI - Caesium chloride in the preparation of membrane fractions from human cerebral tissue. PMID- 4292810 TI - Electron microscopy of monkey kidney cells infected with both SV40 and measles virus. PMID- 4292812 TI - Effect of saxitoxin on the end plate of frog muscle. PMID- 4292811 TI - Inhibition of fatal anaphylaxis in mice inoculated with a virus-induced leukaemic tumour extract. PMID- 4292813 TI - Nicotinamide adenine dinucleotide and the metabolism of ethanol and acetaldehyde. PMID- 4292814 TI - Some observations on the hazards of corticosteroid therapy in patients with inflammatory bowel disease. PMID- 4292815 TI - The steroid shield in ophthalmology. PMID- 4292816 TI - Semiautomated determination of fluoride in urine. PMID- 4292818 TI - [In vitro study of the influence of glucose on cation exchanges at the level of the rat adrenal under the action of ACTH]. PMID- 4292817 TI - The use of silica gel in source testing. PMID- 4292819 TI - [Influence of glucose and of hypophysectomy on response of the rat adrenal to ACTH in vitro]. PMID- 4292820 TI - [Chromosomal triploidy in a new-born infant with multiple malformations]. PMID- 4292821 TI - Inhibition of Rous sarcoma virus and chicken leukosis viruses by 1-adamantanamine hydrochloride. PMID- 4292822 TI - Parainfluenza 1 (Sendai) antibodies and mumps vaccination. PMID- 4292823 TI - Distribution of neuraminidase among food-poisoning strains of Clostridium perfringens. AB - A survey was made to determine the distribution of the enzyme neuraminidase among 76 strains of Clostridium perfringens. Representative strains from each toxigenic type (A to F) and atypical C. perfringens type A food-poisoning strains of both American and English (Hobbs types) origin were tested. Both the American food poisoning and nonfood-poisoning associated cultures consisted of both neuraminidase-positive and -negative strains. Furthermore, American strains which could not be differentiated from the original Hobbs cultures consisted of both neuraminidase-positive and -negative representatives. In contrast, the English (Hobbs) strains uniformly failed to produce an active intracellular or extracellular neuraminidase. No enzyme activity was detected in these strains when cultures were grown in different growth media, when grown in the presence of substrate (neuraminlactose), or upon extended incubation of enzyme preparations with substrate. With the exception of a type F strain, representative strains of the other toxigenic types (A to F) produced neuraminidase; 85% of the typical type A strains contained the enzyme. PMID- 4292824 TI - Sporulation of Clostridium perfringens in a modified medium and selected foods. AB - A modified sporulation medium for Clostridium perfringens was formulated in which a larger number of spores were produced than in SEC broth and in which spores of greater heat resistance were produced than in Ellner's medium when it was also used as the suspending medium. This modified medium consisted of 1.5% peptone; 3.0% Trypticase; 0.4% starch; 0.5% NaCl; and 0.02% MgSO(4). The addition of 0.1% sodium thioglycolate and 0.0001% thiamine hydrochloride was optional. The optimal temperature for sporulation of five strains was 37 C in comparison with 5, 22, and 46 C. Sporulation had occurred by 6 hr and was essentially complete after 20 hr at 37 C. Noyes veal broth without glucose also supported the formation of heat resistant spores but in smaller numbers than did the modified medium. Very low numbers of spores, or none, were produced under the same conditions in pea or tuna slurries. PMID- 4292826 TI - Incorporation of liquid hydrocarbons into agar media. PMID- 4292825 TI - Quantitative studies on fabrics as disseminators of viruses. 3. Persistence of vaccinia virus on fabrics impregnated with a virucidal agent. AB - Eight compounds were tested in vitro for virucidal and antiviral activity against poliovirus and vaccinia virus. These compounds included five quaternary ammonium salts, two bromosalicylanilides, and neomycin sulfate, an antibiotic. None of the compounds was active against poliovirus, but virucidal activity was demonstrated against vaccinia virus with three of the quarternary ammonium compounds: n-alkyl (C14, C12, C16) dimethyl benzyl ammonium chloride, di-isobutyl cresoxy ethoxy ethyl dimethyl benzyl ammonium chloride monohydrate, and n-alkyl (60% C14, 30% C16, 5% C12, 5% C18) dimethyl benzyl ammonium chlorides plus n-alkyl (50% C12, 30% C14, 17% C16, 3% C18) dimethyl ethylbenzyl ammonium chlorides. Wool blanketing, wool gabardine, and cotton sheeting materials were impregnated with the first of the above virucidal compounds, and the persistence of vaccinia virus on these fabrics was compared with the persistence of the agent on nonimpregnated fabrics of the same type held at 25 C in 35 and 78% relative humidity. No virus could be recovered from the chemically treated fabrics at any time after virus exposure, whereas the virus persisted as long as 4 weeks on nonimpregnated materials. Viable vaccinia virus was also found to persist less than 1 day on a cotton fabric finished with a wash-and-wear modified triazone resin. Poliovirus persisted less than 5 days on this wash-and-wear fabric. PMID- 4292827 TI - Effects of calcium-deficient perfusion on isolated mesenteric arteries. PMID- 4292828 TI - Transmission of sensory information through the lemniscal pathway during sleep. PMID- 4292829 TI - Presynaptic and postsynaptic inhibition of transmission of somatic afferent volleys through the cuneate nucleus during sleep. PMID- 4292830 TI - Vestibular influences during sleep. V. Vestibular control on somatic afferent transmission in the cuneate nucleus during desynchronized sleep. PMID- 4292831 TI - Metabolite repression of fructose 1,6-diphosphatase in yeast. PMID- 4292832 TI - Identification of sulfur as component of the EPR signal at g equals 1.94 by isotopic substitution. PMID- 4292833 TI - Polynucleotide phosphorylase: structure and mechanism of action. PMID- 4292834 TI - Comparative studies on the activity of carboxylases and other enzymes in relation to the new pathway of photosynthetic carbon dioxide fixation in tropical grasses. AB - 1. The activity per unit of chlorophyll of certain carboxylases, and of other enzymes involved in photosynthesis, was determined in leaf extracts of the tropical grasses, sugar-cane, maize and sorghum, and compared with the activities for wheat, oat and silver-beet. Maximum rates of photosynthetic carbon dioxide uptake were also measured for comparison with enzyme activities. 2. Phosphopyruvate carboxylase activity was about 60 times greater in the tropical grasses than in wheat, oat and silver-beet and was severalfold higher than the rates of photosynthetic carbon dioxide uptake. Most of the enzyme was located in the chloroplast fraction of cell extracts. 3. Phosphopyruvate carboxylase was apparently the major photosynthetic carbon dioxide-fixing enzyme in the tropical grasses, although malic enzyme may contribute to a lesser extent. 4. Tropical grasses contained less than one-tenth of the ribulose diphosphate carboxylase activity present in wheat, oat and silver-beet. For the tropical grasses this activity, determined with a saturating concentration of bicarbonate, was approx. 10% of the rate of photosynthesis. 5. The fraction-1 protein content of leaf extracts paralleled the ribulose diphosphate carboxylase activity. 6. In contrast, the activity of several other enzymes of the Calvin cycle was similar in the different species examined. PMID- 4292836 TI - Ubiquinone deficiency in an auxotroph of Escherichia coli requiring 4 hydroxybenzoic acid. AB - 1. Escherichia coli 156:53D2 synthesized ubiquinone only when the growth medium was supplemented with 4-hydroxybenzoate acid. 2. Little or no vitamin K(2) was formed by the mutant under the growth conditions employed, in contrast with wild type strains. 3. In the mutant ubiquinone deficiency was correlated with low respiration and with low particulate NADH-oxidase and NADH-cytochrome b(1) reductase activity. 4. Preincubation of ubiquinone-deficient particles with ubiquinone-30 largely restored the NADH-oxidase and NADH-cytochrome b(1) reductase activities. 5. Various NADH-dye-linked reductases which may be associated with NADH dehydrogenase were not affected by the absence of ubiquinone. 6. The succinate-oxidase complex was less affected than the particulate NADH oxidase by ubiquinone deficiency. 7. A pathway for electrons in the NADH-oxidase complex of the auxotroph of E. coli is proposed and its relationship to the pathway in the wild-type strain is discussed. PMID- 4292837 TI - The role of aminoacetone in L-threonine metabolism by Bacillus subtilis. PMID- 4292835 TI - A continuous recording technique for the measurement of carbon dioxide, and its application to mitochondrial oxidation and decarboxylation reactions. AB - 1. A technique is described for continuously recording the concentration of carbon dioxide in mitochondrial suspensions. 2. The oxidation of palmitoylcarnitine by rat-liver mitochondria inhibits the oxidation of pyruvate and isocitrate, and stimulates the carboxylation of pyruvate. 3. These effects of palmitoylcarnitine oxidation are reversed by the uncoupling agent pentachlorophenol. 4. The effects of palmitoylcarnitine oxidation and pyruvate oxidation on the acylation of mitochondrial coenzyme A and reduction of nicotinamide nucleotides were measured. 5. Control mechanisms are discussed for the interactions between palmitoylcarnitine oxidation and the tricarboxylic acid cycle in rat-liver mitochondria. PMID- 4292838 TI - Liver enzyme changes in the developing rat. PMID- 4292839 TI - A nuclear magnetic resonance study of substrate binding by alcohol dehydrogenases. PMID- 4292840 TI - The effect of iodination upon the catalytic and regulatory activities of fructose 1,6-diphosphatase. PMID- 4292841 TI - Rat liver D-beta-hydroxybutyrate dehydrogenase. I. Partial purification and general properties. PMID- 4292842 TI - Rat liver D-beta-hydroxybutyrate dehydrogenase. II. Lipid requirement. PMID- 4292843 TI - Mitochondrial respiration under conditions of varying osmolarity. PMID- 4292844 TI - Utilization of respiratory substrates in calf-retina mitochondria. PMID- 4292845 TI - Oscillations of nucleotides and glycolytic intermediates in aerobic suspensions of Ehrlich ascites tumor cells. PMID- 4292846 TI - Dietary response of various key enzymes related to glucose metabolism in normal and diabetic rat liver. PMID- 4292847 TI - Phosphates and phosphatases in preosseous cartilage. PMID- 4292848 TI - The composition of bovine cartilage and bone. PMID- 4292849 TI - [Studies on the clinical use of diallylnortoxiferine (Alloferin)]. PMID- 4292850 TI - [Research on the oncogenic power of 3 zones with hemagglutinating activity, obtained by centrifugation of purified polyoma virus in density gradient of cesium chloride]. PMID- 4292851 TI - Acid resistance and infectivity of food-poisoning Clostridium perfringens. PMID- 4292852 TI - Sensitivity to, and production of interferon by three variants of Mengo virus. PMID- 4292854 TI - Studies on the toxicity of polymyxin B to blue-green algae. PMID- 4292853 TI - Certain physical and chemical properties of two murine leukemia viruses. PMID- 4292856 TI - Tetraethylammonium-induced contractions of frog's skeletal muscle. I. General considerations. PMID- 4292855 TI - On the contractile response of the isolated rat uterus to prostaglandin E1. PMID- 4292857 TI - Tetraethylammonium-induced contractions of frog's skeletal muscle. 3. Mechanism of action by calcium release. PMID- 4292858 TI - A micromethod for measurement of renin in the plasma and kidney of rats. PMID- 4292859 TI - Note on the preparation of renin substrate. PMID- 4292860 TI - Phosphatidyl glycerophosphate phosphatase. AB - An enzyme (phosphatidyl glycerophosphate phosphatase) that catalyzes the formation of phosphatidyl glycerol from phosphatidyl glycerophosphate has been rendered soluble by treatment of the particulate fraction of E. coli with Triton X-100 in the presence of EDTA, and has been partially purified. The enzyme is specific for phosphatidyl glycerophosphate and does not catalyze the hydrolysis of other simple phosphomonoesters. It requires Mg(++) for activity and is inhibited by sulfhydryl agents. Some other properties of the enzyme are also described. PMID- 4292861 TI - A simplified preparation of phosphatidyl inositol. AB - A method is described for the rapid isolation of phosphatidyl inositol from soybean phosphatides (Asolectin). The product is obtained pure as the crystalline sodium salt. PMID- 4292862 TI - Internal standards in the estimation of acetyl-CoA in liver extracts. AB - The necessity for adding an internal standard to liver extracts during fluorimetric estimation of acetyl-CoA by the malic dehydrogenase-citrate synthase reaction is demonstrated. Addition of acetyl-CoA completely compensates for the inhibitory action of some tissue components. Values for hepatic acetyl-CoA in fed and fasted rats are given. PMID- 4292863 TI - Concurrent measurement of renin and angiotensin in the circulation of the dog. PMID- 4292864 TI - Diurnal variation of adrenocortical function in hypophysectomized rats with multiple heterotopic pituitary homografts. PMID- 4292866 TI - PAS-positive erythroblasts in kidney diseases. PMID- 4292865 TI - Enzyme mechanism of aminoacetone metabolism by micro-organisms. PMID- 4292867 TI - Hereditary methemoglobinemia due to DPNH-methemoglobin reductase deficiency: report of a family. PMID- 4292868 TI - Hematological and serological behaviour of chicks inoculated with myeloblastosis virus. PMID- 4292869 TI - Cytological diagnosis of generalized cytomegalic inclusion disease. PMID- 4292870 TI - [Association of an anatomo-pathological syndrome of male pseudohermaphroditism, Wilms' tumor, parenchymatous nephropathy and XX/XY mosaicism]. PMID- 4292871 TI - [Further experimental studies on the catecholamine metabolism in extrapyramidal diseases (Parkinson and chorea syndromes)]. PMID- 4292872 TI - Lipolytic action of 3,3'5-triiodo-L-thyronine, a cyclic AMP phosphodiesterase inhibitor. PMID- 4292873 TI - Functional activity of DNA and DNA polymerase during thymine starvation of Escherichia coli 15T. PMID- 4292874 TI - Studies on alkaline phosphatase. Inhibition by phosphate derivatives and the substrate specificity. AB - 1. The kinetics of inhibition of calf-intestinal alkaline phosphatase by inorganic phosphate, fluorophosphate, inorganic pyrophosphate, beta glycerophosphate and adenosine 5'-triphosphate in the range pH8-10 were investigated. The reference substrate was 4-methylumbelliferyl phosphate. 2. The inhibitions were ;mixed' in that both K(m) and V were affected, but the competitive element was by far the stronger. 3. In each case the pH profile for the competitive K(i) was similar to the pH profile for K(m). Since the K(m) and K(i) values both change 100-fold over the pH range 8-10, it is concluded that the inhibitors compete with the substrate for the same active site. 4. It was also found that the enzyme preparation hydrolysed fluorophosphate, pyrophosphate and adenosine 5'-triphosphate as readily as it hydrolysed 4-methylumbelliferyl phosphate and beta-glycerophosphate. Each pH-activity curve, however, had a different shape, but with the exception of pyrophosphate the activity approached the same maximum value at high pH. 5. Attempts to separate the phosphomonoesterase and pyrophosphatase activities by column chromatography were not successful, and the results of other experiments listed suggest that the two activities are a property of the same enzyme. 6. The effect of Mg(2+) ions is briefly mentioned: the phosphomonoesterase activity is enhanced whereas the pyrophosphatase and adenosine triphosphatase activities are strongly inhibited in the presence of excess of Mg(2+) ions. PMID- 4292875 TI - Inhibition of glycolytic enzymes of normal and neoplastic liver by free fatty acids. PMID- 4292876 TI - Inhibition of liver microsomal inorganic pyrophosphate-glucose phosphotransferase and glucose 6-phosphate phosphohydrolase activities by metal-binding agents. PMID- 4292877 TI - Control of citrate formation in rat liver by the nicotinamide-adenine dinucleotide redox state. PMID- 4292878 TI - Nicotinamide-adenine dinucleotide-specific isocitrate dehydrogenase from pea mitochondria. PMID- 4292879 TI - Characteristics of the binding of rotenone in the respiratory chain and the inhibition sites of amytal and piericidin A. PMID- 4292880 TI - The phospholipid composition of embryonic chick liver microsomes. AB - 1. The phospholipid composition of hepatic microsomal fractions from different developmental stages of embryonic chick was established. The major components were phosphatidylcholine (approx. 66%), phosphatidylethanolamine plus phosphatidylserine (approx. 21%) and sphingomyelin (approx. 9%). 2. There were no significant changes in the phospholipid composition during embryonic development from 9 to 20 days. 3. When microsomal subfractions were prepared it was found that the smooth-microsomal fractions (Ia and Ib) had a significantly greater sphingomyelin content than the rough-microsomal fraction (II). This was compensated by a lower phosphatidylcholine content in fractions Ia and Ib and an increase of phosphatidylcholine in fraction II. 4. The significance of the differences in the phospholipid composition of smooth and rough microsomes is discussed with particular reference to the origin and interrelation of smooth and rough endoplasmic reticulum. PMID- 4292881 TI - Inhibition of alcohol dehydrogenase from yeast by pyridine. AB - 1. Inhibition by pyridine of reduction of NAD by ethanol in the presence of yeast alcohol dehydrogenase was studied at 25 degrees in 60mm-glycine buffer (K(+), pH9.3). 2. The apparent Michaelis constant for ethanol increases linearly and that for NAD increases non-linearly with pyridine concentration. 3. Rates, v, observed in the presence of pyridine are lower than the values calculated from the effect of pyridine on the two apparent Michaelis constants and are described by the expression V/v={1+5.8[pyridine]}x{1+0.016(1+124 [pyridine)]/[EtOH]}x{1+0.00019(1+3.3[pyridine]+110 [pyridine](2))/[NAD]}. 4. Mixed inhibitor studies with pyridine and N(1)-methylnicotinamide chloride in 40mm-pyrophosphate buffer (Na(+), pH8.2) indicated little interaction of pyridine with the ;pyridinium site' of the dehydrogenase (interaction constant, alpha, 2.1). 5. The possible competition of ethanol and pyridine for a zinc atom in the active centre of yeast alcohol dehydrogenase is discussed. PMID- 4292882 TI - Isolation and amino acid composition of human angiotensin I. AB - 1. Angiotensin, the most powerful pressor substance known, suspected to be a causal substance in renal hypertension and previously isolated from animal sources, has now been isolated from human sources and the amino acid composition was analysed. 2. The procedures followed in the successful isolation of human angiotensin include: (a) preparation of stable materials to obtain maximum formation of human angiotensin; (b) a relatively selective adsorption of the formed angiotensin on Dowex 50W (X2); (c) gel filtration through Sephadex G-25; (d) cation-exchange chromatography on CM-cellulose; (e) anion-exchange gel filtration on DEAE-Sephadex A-25; (f) molecular-sieve chromatography through Bio Gel P-2. 3. The homogeneity of the human angiotensin isolated was confirmed by paper and thin-layer chromatography and paper electrophoresis. 4. The biological activity observed indicates the substance isolated to be human angiotensin I. 5. The amino acid analysis suggested the following proportional composition: Asp, 1; Pro, 1; Val, 1; Ile, 1; Leu, 1; Tyr, 1; Phe, 1; His, 2; Arg, 1. This composition is similar to that of horse angiotensin I, i.e. isoleucine(5)-angiotensin I. PMID- 4292883 TI - The contaminating effects of cephalins in estimating non-esterified fatty acids. PMID- 4292884 TI - Effects of insulin and phospholipase A on glucose transport across the plasma membrane of free adipose cells. PMID- 4292885 TI - Enzyme specificity in the stimulation of glucose transport in free adipose cells by phospholipases. PMID- 4292886 TI - On the nature of endogenous substrate in rat-liver mitochondria. PMID- 4292887 TI - Inhibition by formaldehyde of energy transfer and related processes in rat-liver mitochondria. PMID- 4292889 TI - The cytochrome system of Azotobacter vinelandii. PMID- 4292888 TI - Nitrite metabolism by skeletal muscle mitochondria in relation to haem pigments. PMID- 4292890 TI - Highly purified cytochromes C derived from the diatom, Navicula pelliculosa. PMID- 4292891 TI - Purification and some properties of cytochrome c dervied from the marine worm, Dendrostomum zostericolum. PMID- 4292892 TI - NADH oxidation by hypoxanthine dehydrogenase of avian kidney. PMID- 4292893 TI - [Degradation and resynthesis of the active sites of plant ferredoxins]. PMID- 4292894 TI - Cholinergic inhibition in the cerebral cortex. PMID- 4292895 TI - [Very severe hepatic coma in acute hepatitis in a 11-year-old child treated successfully by repeated exchange blood transfusions]. PMID- 4292897 TI - [Study of the molecular weight of human interferons from different tissues]. PMID- 4292896 TI - [Presence of viral particles in the organs of the NZB mouse]. PMID- 4292898 TI - Clostridium perfringens as a pathogen of cattle: a literature review. AB - Reports of Cl. perfringens as a pathogen for cattle are reviewed and discussed. PMID- 4292899 TI - Effect of incubation temperature and serum content in agar overlay on plaque production by foot-and-mouth disease virus. AB - The numbers of plaques produced by foot-and-mouth disease virus in primary cultures of calf kidney cells conditioned to 24, 30, and 37 C were essentially the same if virus was absorbed at 37 C. Adsorption was as effective at 30 as at 37 C in cultures conditioned to the respective temperature, but 24 C was less effective under this condition. However, when the adsorption temperature for cultures conditioned to 37 C was decreased to 30 or 24 C, fewer plaques were produced than in cultures conditioned to and maintained at the lower temperatures during absorption. Comparison of the number of plaques produced in cultures overlaid with nutrient agar containing from 0.5 to 10% bovine serum revealed no difference in relation to serum concentration. However, plaque size was related directly to the concentration of serum in the overlay. PMID- 4292900 TI - A survey of the alimentary tract of cattle for Clostridium perfringens. AB - Contents of the rumen, abomasum, ileum, and colon of 100 fattened cattle were examined for the presence of Cl. Perfringens. Liquid medium iniculated with each sample of gut content was tested for the presence of toxins of Cl. Perfringens. Identification of Cl. Perfringens was based on atmospheric requirements for growth, colonial morphology, and stormy fermentation in litmus milk. Identification of toxins was based on neutralization tests in guinea pigs and mice.Cl. Perfringens was isolated from 202 of 399 samples. In 105 additional cultures, colonies characteristic of Cl. Perfringens were present but could not be isolated in pure culture.Cl. Perfringens type D toxin was identified in only one culture, which was inoculated with ileum contents. Type A toxin was identified in eight of the 24 samples from the one lot of samples in which no type A antitoxin was used. There were no identifications of toxigenic types B, C, or E. The results indicate that an isolation from necropsy specimens of untyped Cl. Perfringens or type A Cl. Perfringens is in itself of little significance. The infrequency of occurrence of the other toxigenic types in this survey of healthy cattle indicates that recovery of these types from necropsy specimens may be of more significance in determining the cause of death. PMID- 4292901 TI - Glyconeogenesis, fructose-1,6-diphosphatase and phosphoenolpyruvate carboxykinase activities of Ascaris lumbricoides adult muscle and larvae. PMID- 4292902 TI - Enzymatic softening of connective tissue sheaths to aid microelectrode penetration. PMID- 4292903 TI - [Convulsion and brain tumor. A contribution to the differential diagnosis of cerebral convulsions]. PMID- 4292904 TI - Studies on the antiviral activity of formycin. PMID- 4292905 TI - [Isolation of kanamycin or viomycin-resistant M. tuberculosis from tuberculous patients]. PMID- 4292906 TI - Discharge patterns of neurones supplying tonic abdominal flexor muscles in the crayfish. PMID- 4292907 TI - Histochemical patterns in the proventriculus of the developing chick. PMID- 4292908 TI - Nature of thalamo-cortical relations during spontaneous barbiturate spindle activity. AB - 1. The relation between thalamic and cortical spontaneous spindles was investigated in cats anaesthetized with barbiturates.2. Simultaneous recordings with multiple electrodes in the thalamus and cortex revealed a high correlation between thalamic and cortical spindle activity, both with regard to the occurrence of the spindles as well as to their individual waves, provided a critical location of the electrodes was secured. The results indicate a point-to point relation between a group of thalamic cells and a small cortical area to which these cells project. In the spontaneous rhythm, the cortical columns are probably individually controlled by a thalamic rhythmic entity. This point-to point relation was found in all the major sensory projection systems and in one thalamic ;association' nucleus and its corresponding ;association' cortex.3. Cortical barbiturate spindles appeared either as local spindles in a restricted cortical area or as compound spindles in several areas. Spindles recorded from electrodes separated by 2 mm or more were clearly different with regard to intraspindle wave frequency, duration, and the time of start and stop of the spindle. These differences increased with increasing distance between the electrodes, and were most pronounced when the corticograms of the two hemispheres were compared.4. Spontaneous spindle activity interfered with orthodromic transmission through n. ventralis posterolateralis (VPL) and medial geniculate nucleus (MG), judged by depression of the thalamic and cortical responses to peripheral nerve volleys or clicks. Such inhibition required the afferent volley to be delivered at a particular time of the spontaneous oscillations. Further, orthodromic volleys reset the rhythmic spindle waves in the appropriate thalamic and cortical areas.5. These findings lead to a new concept of the thalamic pace maker function. During barbiturate anaesthesia, small assemblages of thalamic neurones seem to have the ability to generate independent rhythmic discharges, and thereby control the rhythm of the particular cortical column to which this thalamic group projects.6. During barbiturate anaesthesia, many facultative pace makers seem to be present in the thalamus. The total number may be as large as 25,000-35,000. Usually, many of these rhythmic thalamic units beat in synchrony or near synchrony. PMID- 4292910 TI - Aldosterone and angiotensin action on water absorption in the rat jejunum. PMID- 4292909 TI - Micro-iontophoretic studies on neurones in the cuneate nucleus. AB - 1. Cuneate cells in anaesthetized cats were strongly excited by L-glutamate, and somewhat less by D-glutamate; cells which receive afferents from hair receptors were particularly sensitive.2. Glutamate could be used to demonstrate post synaptic inhibitory inputs from the dorsal column, the medial lemniscus and the frontal cortex.3. Many cuneate cells were also strongly excited by adenosinetriphosphate (ATP); this was probably due to the chelating action of ATP, as citric acid was also quite effective.4. gamma-Aminobutyric acid (GABA) readily blocked all forms of spontaneous and evoked activity, except antidromic invasion of cuneothalamic neurones; cells which receive proprioceptive afferents were particularly sensitive to GABA. Glycine had a comparable effect.5. Acetylcholine (ACh), catecholamines, histamine, 5-hydroxytryptamine (5-HT) and an extract containing substance P mostly had only weak depressant actions. Cholinergic and mono-aminergic mechanisms are probably not very significant in the cuneate.6. These results are consistent with the possibility that glutamate and GABA (or glycine), or some closely related compounds, are the main excitatory and inhibitory transmitters in the cuneate nucleus.7. If ATP is released from afferent nerve endings, it could also play a significant role in excitation. PMID- 4292911 TI - Post-tetanic increase in frequency of miniature end-plate potentials in calcium free solutions. PMID- 4292912 TI - Ionic requirements of synaptic transmitter release. PMID- 4292913 TI - [Isosexual precocity]. PMID- 4292914 TI - [Conference on the handling of cardiology information. (Paris, December 16, 1965)]. PMID- 4292915 TI - [The allergic factor in hepato-biliary migraine]. PMID- 4292916 TI - [Rheumatism and cancer]. PMID- 4292917 TI - [Articular cartilage. Problems of histophysiology and physiopathology]. PMID- 4292918 TI - [The infectious factor in hemorrhoidal disease]. PMID- 4292920 TI - [Bacterial and fungus infections during the course of acute leukemias]. PMID- 4292919 TI - [Histocytologic comparison in the diagnosis of hematosarcomas]. PMID- 4292921 TI - [Fibrinogen disorders in acute leukemias]. PMID- 4292922 TI - [The effectiveness of platelet transfusions]. PMID- 4292923 TI - [Adoptive immunotherapy (by bone marrow graft or leukocyte transfusion) of acute leukemias]. PMID- 4292924 TI - [Acute and recurrent gastroduodenal pseudo-dilatation caused by small cell jejunal epithelioma]. PMID- 4292925 TI - [Diazepam in chronic epilepsy]. PMID- 4292926 TI - New surgical approach to nasopharyngeal angiofibromas. PMID- 4292927 TI - Crystalline vitamin D3 for the prevention of milk fever in cattle. PMID- 4292928 TI - The safety of massive doses of vitamin D3 in the prevention of milk fever. PMID- 4292929 TI - [Problems of anesthesia and recovery in the surgical treatment of pancreatic islet tumors]. PMID- 4292930 TI - Cytochemical and autoradiographic investigations on normal and myelomatous plasma cells. PMID- 4292931 TI - The significance of mutual adhesiveness of cells in the histological pattern of cancer tissues. PMID- 4292932 TI - The function of the adrenal cortex in mice with spontaneous adrenocortical lipid depletion. PMID- 4292934 TI - [Determination of the activity of plasma lactic dehydrogenase. Role of the leukocytes]. PMID- 4292933 TI - [Enzymatic determination of blood triglycerides]. PMID- 4292935 TI - A modification of the biologic test for tuberculosis with silica-treated guinea pigs. PMID- 4292936 TI - [On the problem of optimal reaction conditions in the histochemical demonstration of enzymes of energy-producing metabolism in the epidermis. II. Aldolase, tetrazolium reductase, cytochrome oxidase, ubiquinone]. PMID- 4292937 TI - A tissue-specific shift in lactate dehydrogenase sub-band patterns of the house mouse. PMID- 4292938 TI - The subcellular localization of factor VII (proconvertin) in rat liver. PMID- 4292939 TI - [Chemotherapy of malignant brain tumors by intermittent and continuous intra arterial infusion of antitumor agents--clinical study]. PMID- 4292941 TI - [Action of digitonin on murine leukomogenic virions]. PMID- 4292942 TI - [Probable existence of 2 RNA-replicases in poliovirus]. PMID- 4292940 TI - The release of catecholamines from the adrenal medulla by peptides. PMID- 4292943 TI - [On the cytochemistry of the idiosome and of the acrosome in rodents]. PMID- 4292945 TI - [Demonstration of a variant of vesicular stomatitis virus (Indiana strain) conferring a delayed sensitivity to carbon dioxide gas in Drosophila melanogaster]. PMID- 4292944 TI - [Embryonal antigens and cancer of the liver in man. Association of serum alpha 1 fetoprotein with primary hepatoma]. PMID- 4292946 TI - [Influence of the orthophosphate ion and of various sources of phosphorus on chromogenesis in Pseudomonas aeruginosa]. PMID- 4292947 TI - [Enzymatic activities in the small intestine of the lamb. (Acid and alkaline phosphatases, glucose-6-phosphatase, alpha-D-methylglucosidase, invertase and lactase)]. PMID- 4292948 TI - [Changes of the glycogenic content, phosphorylase and glucose-6-phosphatase activities at the level of the neurohypophysis]. PMID- 4292949 TI - The incidence and significance of bovine herpesvirus (infectious bovine rhinotracheitis) antibodies in the sera of aborting cattle. AB - The results of bovine herpesvirus (IBR-IPV) neutralization tests conducted on the sera of 463 animals with a prior history of undiagnosed abortion and 331 control animals with no history of abortion are reported. One hundred and thirty-one (28.3 per cent) of the aborting and 105 (31.7 per cent) of the control animals, were found to harbour antibody to this virus. No significant seasonal or gestational incidence could be determined but some variation in the annual incidence was apparent. On the basis of these results it appears unlikely that this virus is responsible for a significant proportion of the undiagnosed cases of bovine abortion in Quebec and Ontario, where the animals tested were located. The problems involved in substantiating a diagnosis of abortion due to bovine herpesvirus are briefly discussed. PMID- 4292951 TI - Histological observations on pituitary ACTH-cells, adrenal cortex, and the corpuscles of stannius of the european eel (Anguilla anguilla L.). PMID- 4292950 TI - [Hypophosphatasia]. PMID- 4292952 TI - Nephroblastoma. A clinical study of 26 cases. PMID- 4292953 TI - The new method of suturing traumatic peripheral nerve paralysis. PMID- 4292954 TI - Isolation of a collagenolytic enzyme from Mycobacterium tuberculosis. PMID- 4292955 TI - Lack of cytochrome oxidase in yeast cells deficient in pantothenate. PMID- 4292956 TI - Tissue interactions in the development of ptilopody and brachydactyly in the chick embryo. PMID- 4292957 TI - A comparative study on avian adrenocortical response to exogenous and endogenous corticotropin. PMID- 4292960 TI - [Diagnosis and therapy of mammary gland tumors]. PMID- 4292958 TI - The margin of safety of neuromuscular transmission. AB - 1. The margin of safety for neuromuscular transmission in the tibialis and sartorius muscles of the cat has been determined by measuring the ratio by which end-plate depolarization produced by succinylcholine, decamethonium, octamethonium or iodocholine is antagonized, in the presence of neuromuscular block produced by tubocurarine, gallamine or DF-596. The estimate of the margin of safety was independent of the particular drugs chosen for the measurement.2. To produce threshold block to indirect stimulation once every 10 sec, a fractional occupancy by the antagonist of 0.76 +/- 0.05 (S.D.) was required; for nearly complete block, an occupancy of 0.917 +/- 0.16 (S.D.) was required. These figures correspond to factors of safety of 4.1 and 12 for the most sensitive and the most resistant groups of fibres respectively.3. The interaction between the agonists and the antagonists, when tested over a wide range of dosage, did not conform with the conditions of full competitive equilibrium. It was concluded that this arose, not because of some interfering non-competitive process, but because, during the relatively brief exposure to agonist, the equilibrium between the antagonist and the receptors is not significantly disturbed. An analysis of this condition of quasi-equilibrium is given. A correction downwards of the direct estimates of the margin of safety is required, but this proves to be small, about 8%, and may not be significant.4. The safety factor diminished when the motor nerve had been cut more than 5 hr; it is suggested that this represents an early sign of nerve degeneration.5. With dog sartorius muscle, results similar to those in the cat were obtained. But for deep block in the rabbit, the safety factor was only about 4.6. The existence of a substantial margin of safety influences considerably the interpretation of the time course of action of blocking drugs, and of comparisons between responses to nervous excitation and drug injection. PMID- 4292959 TI - [Studies on the sensitivity of swine anti-serum against Japanese encephalitis virus to 2-mercaptoethanol. (1)]. PMID- 4292961 TI - [Modern diagnosis of peripheral nerve diseases]. PMID- 4292962 TI - Transformation of polyploid hamster cells by polyoma virus. PMID- 4292963 TI - Growth of cell-strains and primary cells on micro-carriers in homogeneous culture. PMID- 4292964 TI - Silica in the wall of Pediastrum. PMID- 4292965 TI - Amnesia induced by scopolamine and its temporal variations. PMID- 4292966 TI - [Antipeptidase drugs and anti-inflammatory activity]. PMID- 4292967 TI - [Tyramine and sympathetic transmission at the level of the deferens in the guinea pig]. PMID- 4292968 TI - [On the determinism of the "stretch syndrome" in animals. Specificity of action of the ACTH molecule]. PMID- 4292969 TI - [The hypothalamus and the extrahypothalamic structures which control the anterior pituitary]. PMID- 4292970 TI - [Some aspects of the action of angiotensin on the kidney]. PMID- 4292971 TI - [Angiotensin and its vasopressive action. I. Experimental study in the rat]. PMID- 4292972 TI - [Angiotensin and its vasopressive action. II. Action of angiotensin in normal and hypertensive humans]. PMID- 4292973 TI - On the nature of free radicals induced by X-rays in puric bases. PMID- 4292974 TI - Sensitized photodimerization of thymine in DNA. PMID- 4292975 TI - Complement-fixing antibodies in sera of human and nonhuman primates to viral antigens derived from Burkitt's lymphoma cells. PMID- 4292976 TI - The histocompatability-2 locus and susceptibility to bittner virus borne by red blood cells in mice. PMID- 4292977 TI - The genetic heterogeneity of simian virus 40. PMID- 4292978 TI - Intraspinal tumours in children. PMID- 4292979 TI - [Study of ovarian and adrenal function in the course of Sheehan's disease]. PMID- 4292980 TI - The significance of abnormal bacterial proliferation in the gastrointestinal tract after gastric surgery. PMID- 4292981 TI - [Female gout. (Analysis of 40 cases)]. PMID- 4292982 TI - [Therapy of gout with allopurinol. (Study of 106 cases)]. PMID- 4292983 TI - [Allopurinol treatment of gout with renal insufficiency]. PMID- 4292984 TI - [The effects of allopurinol in gout patients with uric urinary lithiasis or hyperuraturia]. PMID- 4292985 TI - [The action of ethanol in gout and on the metabolism of uric acid]. PMID- 4292986 TI - [What are the errors to avoid in the treatment of chronic respiratory insufficiency?]. PMID- 4292987 TI - [Isoniazid-pyridoxine combination in the treatment of tuberculosis]. PMID- 4292988 TI - [Compressive mediastinal tubercular adenopathies: difficulty of diagnosis]. PMID- 4292989 TI - [Ocular hemorrhages and capillary fragility]. PMID- 4292990 TI - [The problem of transitory or dissociated tuberculin allergies in pediatrics]. PMID- 4292991 TI - [Pulmonary infarct during treatment with an oral contraceptive (norethylnodrel + mestranol)]. PMID- 4292992 TI - [On the hyperosmolar comas of diabetes mellitus]. PMID- 4292993 TI - [The Achilles reflexogram in the diabetic]. PMID- 4292994 TI - [An atypical site of drepanocytic osteonecrosis]. PMID- 4292995 TI - [Drug-induced nephropathies]. PMID- 4292996 TI - Adrenergic transmission of the carotid chemoreceptor impulses in the toad. PMID- 4292997 TI - Occasional appearance of diphosphopyridine nucleotide in urine of patients with progressive muscular dystrophy. PMID- 4292998 TI - Bovine papular stomatitis, pseudocowpox and milker's nodules. PMID- 4292999 TI - Achromatic regions of tetrazolium stained starch gels: inherited electrophoretic variation. PMID- 4293000 TI - Management of benign trophoblastic tumors. PMID- 4293001 TI - Accidental Q-switched laser lesion of human macula. PMID- 4293002 TI - Newer compounds in therapy of herpes simplex keratitis. PMID- 4293003 TI - Experimental stromal herpes simplex keratitis in rabbits. PMID- 4293004 TI - Herpes genitalis; clinical and virological studies. PMID- 4293005 TI - [Contribution to the inhibition in vitro and in vivo of autoantibodies]. PMID- 4293006 TI - Ultrathin frozen sections. II. Demonstration of enzymic activity. AB - Endogenous enzyme activity can be readily and routinely demonstrated in ultrathin, frozen sections for electron microscopy. The procedure employed to obtain the best structural preservation as well as enzyme activity in thin sections involved fixation in glutaraldehyde, embedding in thiolated gelatin or pure gelatin, partial dehydration in glycerol, and sectioning in a cryostat at 35 degrees C with a slightly modified Porter-Blum microtome on which the tissue is maintained at -70 degrees C and the knife at -23 degrees C. Kidney cortex was used as test tissue, but a few other organs were occasionally used. Thin sections were floated on the surface of several incubation media routinely employed for enzyme cytochemistry. Positive, specific reactions were obtained for alkaline phosphatase in kidney brush border, for adenosine triphosphatase in brush border and in basal membranes of distal tubules, for acid phosphatase and esterase in lysosomes, and for NADH diaphorase in mitochondria. Mitochondrial ATPase was sporadically evident only in the distal tubule of the kidney. Localizations of enzyme activity reported by other technical approaches were confirmed and in some cases somewhat improved. PMID- 4293007 TI - Ultrastructural demonstration of cytochrome oxidase activity by the Nadi reaction with osmiophilic reagents. AB - A new method for the subcellular and cytochemical demonstration of cytochrome oxidase has been developed with the introduction of N-benzyl-p-phenylenediamine (BPDA) and the discovery that indoanilines are osmiophilic. These indoanilines produced upon oxidation of BPDA in the presence of naphthols are highly colored compounds that yield electron-opaque coordination polymers of osmium (osmium black) that are amorphous, insoluble in water, and in organic solvents. The best methods for preparing rat tissue were in decreasing order: fixation in formaldehyde solution, fresh tissue slices, and frozen sections of fresh or fixed tissue. Ultrathin sections were counterstained by bridging with the thiocarbohydrazide-osmium tetroxide (T-O) procedure for enhancing underlying membranous structures. Cytochrome oxidase activity was noted primarily in mitochondria and occasionally in sarcotubules of heart, in mitochondria and occasionally in infoldings of the plasma membrane of renal tubular cells, and in mitochondria and, to a great extent, in endoplasmic reticulum of hepatic cells. Cytochrome oxidase activity produced deposits in droplet form, whereas dehydrogenase activity resulted in uniform staining of mitochondrial cristae, as recently demonstrated with an osmiophilic tetrazolium salt. Even more recently we have succeeded in demonstrating cytochrome oxidase activity in nondroplet staining on mitochondrial cristae with an osmiophilic benzidine-type reagent that apparently polymerizes upon oxidation (to be published later). PMID- 4293008 TI - Estrogen metabolism in the human. 3. A comparison between females, studied during the first and second halves of the menstrual cycle, and males. PMID- 4293010 TI - On the localization of some phosphatases in three different segments of the proximal tubules in the rat kidney. PMID- 4293009 TI - Lack of glutethimide effect of adrenal. PMID- 4293011 TI - The relationship of menopausal muscular dystrophy to other diseases of muscle. A study of 17 cases. PMID- 4293012 TI - Fatal Mycoplasma pneumoniae infection with isolation of organisms from lung. PMID- 4293013 TI - Pertussis. PMID- 4293014 TI - Group A streptococci, mycoplasmas, and viruses associated with acute pharyngitis. PMID- 4293015 TI - Rhinovirus infections in an industrial population. II. Characteristics of illness and antibody response. PMID- 4293016 TI - Endoplasmic reticulum and the origin of microbodies in fetal mouse liver. PMID- 4293018 TI - Studies on aldehyde fixation. Fixation rates and their relation to fine structure and some histochemical reactions in liver. PMID- 4293017 TI - Correlation of ultrastructure and function following hypothermic preservation of canine kidneys. PMID- 4293019 TI - The renin-angiotensin-aldosterone system in sodium depletion. PMID- 4293020 TI - Dermal erythropoiesis in neonatal infants. A manifestation of intra-uterine viral disease. PMID- 4293021 TI - [Report of the results obtained in the treatment of herpes with a new inactivated vaccine]. PMID- 4293022 TI - [Clinical study of attapulgite]. PMID- 4293023 TI - [Studies on the histotopochemistry of proline oxidation]. PMID- 4293024 TI - Studies on characteristics of poliovirus. II. Plaque-forming capacity of attenuated poliovirus strains in human and monkey kidney cell cultures. PMID- 4293025 TI - Studies on characteristics of poliovirus. 3. Investigation of d, rct, h and n markers of poliovirus isolated after vaccination with the Type 1, Chat strain. PMID- 4293026 TI - Effect of thymectomy on polyoma tumor induction in CF 1 mice. PMID- 4293027 TI - Inoculation of a novel type of rhinovirus (H.S.) to human volunteers. PMID- 4293028 TI - Genetic transfer of guanidine resistance from type 2 to type 1 poliovirus. PMID- 4293029 TI - [On the formation of specific viral SV-40 antigen in the presence of 5-iodo-2' deoxyuridine]. PMID- 4293030 TI - The rabiesviruses--a new group? PMID- 4293031 TI - Factors associated with the response of the cell to herpes simplex virus infection. PMID- 4293032 TI - Antibody response and antigenic difference between high and low oncogenic variants of SE polyoma virus. PMID- 4293033 TI - Synthesis of uncoated viral RNA following picornavirus infection. PMID- 4293035 TI - The organismic theory of tumour formation. PMID- 4293034 TI - [Electron microscopic studies on the development of Herpesvirus hominis in tissue culture cells]. PMID- 4293036 TI - [Contributions to the evaluation of antiphlogistic test results. 2. Comparison of the effects of phenylbutazone with various models of inflammation]. PMID- 4293038 TI - The importance of SH-groups for enzymic activity. V. The coenzyme-binding capacity of pig heart lactate dehydrogenase, isozyme I, after inhibition by various maleinimides. PMID- 4293039 TI - [Stimulation of DPN metabolic processes in ascites tumors by low dosage roentgen irradiation and trenimon]. PMID- 4293037 TI - [On an endopeptidase, hydrolyzing native proteins in the physiological range, from the intestines of Tenebrio molitor. Purification and characterization of the enzyme]. PMID- 4293040 TI - [Partial purification and properties of RNA-polymerase from rat liver]. PMID- 4293041 TI - [Inhibition of aminoacyl-RNA-synthetase activity by sRNA with chemically modified terminal acceptor nucleotide]. PMID- 4293043 TI - [ESR studies of irradiated sulfur-containing and sulfur-free pyridoxine derivatives]. PMID- 4293042 TI - [Deamination of serine and threonine L-isomers in rat and mouse hepatomas]. PMID- 4293044 TI - [Histochemical evaluation of the phosphorylase activity of smooth muscle tissue]. PMID- 4293045 TI - [Antiviral activity in vitro of 5-hydroxytryptophan]. PMID- 4293046 TI - [The use of I-131Na in the study of the pharmacological reactivity of the peripheral blood vessels]. PMID- 4293048 TI - [The determination of fetal body length based upon the measurement of several flat bones]. PMID- 4293047 TI - The histologic identity of adenoma sebaceum and solitary melanocytic angiofibroma. PMID- 4293049 TI - [Current contribution and comparative studies of the determination of fetal body length on the basis of diaphyseal measurement of the bones of the extremities]. PMID- 4293050 TI - [The posterior pituitary gland hormones and pituitary gland-adrenal cortex function]. PMID- 4293051 TI - [Activity of renin/angiotensin system and secretion of aldosterone during pregnancy]. PMID- 4293052 TI - [The axillary lymph nodes in breast carcinoma]. PMID- 4293053 TI - [Lymph nodes changes in man after lymphadenography]. PMID- 4293054 TI - [Reticulo-histiocytoma or multinodular giant cell histiocytosis]. PMID- 4293055 TI - Gamma-butyrolactone and gamma-hydroxybutyric acid. II. The pharmacologically active form. PMID- 4293056 TI - Studies on lipoamide dehydrogenase of Bakers' yeast. 8. Inhibition of enzyme activity by its immune antiserum. PMID- 4293058 TI - [On the corticosteroid-depression]. PMID- 4293057 TI - [Thoughts on after care and rehabilitation in psychiatric patients]. PMID- 4293059 TI - [Neurophysiological problems]. PMID- 4293060 TI - Facilitation at the frog neuromuscular junction during and after repetitive stimulation. PMID- 4293062 TI - [Infectious DNA of the polyoma virus (strain 13)]. PMID- 4293061 TI - [On the problem of direct angiotensin effect on the resorption of sodium in the proximal tubule and Henle's loop of the rat kidney]. PMID- 4293063 TI - [2 years' experience in the work of the Children's Oncological Department]. PMID- 4293064 TI - [Milker's nodes and exanthematous manifestations]. PMID- 4293065 TI - [On the problem of differences between histiocytoma and dermatofibroma in relation to the behavior of the follicle]. PMID- 4293066 TI - [Diminished activity of DPN dependent methemoglobinreductase in erythrocytes of newborn infants as cause of decreased methemoglobin reduction]. PMID- 4293067 TI - Ultrastructural localization of some phosphatases in the prothoracic gland of the insect Leucophaea maderae. PMID- 4293068 TI - Inhibitor o,p'-DDD and vitamin D and dihydrotachysterol function in the chick. PMID- 4293069 TI - Renal function and the renin-angiotensin system in the isolated perfused kidney. PMID- 4293070 TI - Clinical features of adenoviral pneumonia in Air Force recruits. PMID- 4293071 TI - Pure and mixed hilus-cell tumours of ovary. Arris and Gale Lecture delivered at the Royal College of Surgeons of England on 14th November 1966. PMID- 4293072 TI - Herpes simplex virus and paralysis of rabbits. Activation of the paralysis by adrenalin. PMID- 4293073 TI - Studies with angiotensin in nephrogenic diabetes insipidus. PMID- 4293074 TI - Electron microscopic study of the distribution of the mouse leukemia virus (gross) in genital organs of virus-injected C3Hf mice and of AK mice. PMID- 4293075 TI - Chromosomes of "minimal deviation" hepatomas and some other transplantable rat tumors. PMID- 4293076 TI - A difference in sites of DNA synthesis in virus-induced (Shope) and in chemically induced epidermal tumors of rabbit skin. PMID- 4293077 TI - Cellular analysis of liver carcinogenesis: the induction of large hyperplastic nodules in the liver with 2-fluorenylacetamide or ethionine and some aspects of their morphology and glycogen metabolism. PMID- 4293078 TI - Intracellular distribution of 5'-ribonuclease and 5'-phosphodiesterase in the Novikoff hepatoma ascites cells. PMID- 4293079 TI - Evidence for the Calvin cycle and hexose monophosphate pathway in Thiobacillus ferrooxidans. AB - The enzymes of the Calvin reductive pentose phosphate cycle and the hexose monophosphate pathway have been demonstrated in cell-free extracts of Thiobacillus ferrooxidans. This, together with analyses of the products of CO(2) fixation in cell-free systems, suggests that these pathways are operative in whole cells of this microorganism. Nevertheless, the amount of CO(2) fixed in these cell-free systems was limited by the type and amount of compound added as substrate. The inability of cell extracts to regenerate pentose phosphates and to perpetuate the cyclic fixation of CO(2) is partially attributable to low activity of triose phosphate dehydrogenase under the experimental conditions found to be optimal for the enzymes involved in the utilization of ribose-5-phosphate or ribulose-1,5-diphosphate as substrate for CO(2) incorporation. With the exception of ribulose-1,5-diphosphate, all substrates required the addition of adenosine triphosphate (ATP) or adenosine diphosphate (ADP) for CO(2) fixation. Under optimal conditions, with ribose-5-phosphate serving as substrate, each micromole of ATP added resulted in the fixation of 1.5 mumoles of CO(2), whereas each micromole of ADP resulted in 0.5 mumole of CO(2) fixed. These values reflect the activity of adenylate kinase in the extract preparations. The K(m) for ATP in the phosphoribulokinase reaction was 0.91 x 10(-3)m. Kinetic studies conducted with carboxydismutase showed K(m) values of 1.15 x 10(-4)m and 5 x 10(-2)m for ribulose-1,5-diphosphate and bicarbonate, respectively. PMID- 4293080 TI - Distribution of cytochrome c peroxidase activity in wild-type and petite cells of bakers' yeast grown aerobically and anaerobically. AB - Studies of mitochondrial biogenesis in yeast have been hampered by a lack of suitable membrane markers in anaerobically grown cells subsequently grown in air. Cytochrome c peroxidase activity and subcellular location was studied to determine whether it would be a useful marker for an analysis of mitochondrial formation. Cytochemical tests revealed enzyme reaction product on all mitochondrial membranes in aerobically grown wild-type cells. Anaerobically grown wild-type and all petite cultures contained cytochrome c peroxidase cytochemical reaction deposits on abundant cytoplasmic membranes and on the few mitochondrial profiles which also were seen in the electron photomicrographs. Biochemical studies corroborated the cytochemistry because mitochondrial fractions were greatly enriched in cytochrome c peroxidase activity for aerobically grown wild type cultures, but petite and anaerobically grown wild-type cultures showed higher enzyme activities in supernatant fractions than was present in the corresponding particulate fractions after differential centrifugation. Evidence from low-temperature microspectroscopy, spectrophotometric assays of mitochondrial enzyme activities, and electron microscopy showed mitochondrial formation during the time required for preparation and lysis of spheroplasts from anaerobically grown cultures. The data were interpreted as indicating that cytochrome c peroxidase was an oxygen-inducible enzyme, and that there was a developmental relationship between enzyme-reactive membranes of mitochondria and cytoplasm during the period of respiratory adaptation. PMID- 4293081 TI - Fine-structure analysis of intercellular and intracellular mitochondrial diversity in Saccharomyces cerevisiae. AB - Crosses were made between haploid wild-type and suppressive petite strains of bakers' yeast to obtain zygotes for analysis of mitochondrial heterogeneity. Wild type x petite zygotes contained about 40% noncristate mitochondria when immediate mating mixtures were examined. The frequency of defective mitochondria had decreased to an average of 9.2% in 1-week-old zygote isolate cultures, and to 4.4% in slant cultures 1.5 years after initial zygote isolation. The latter value was not significantly different from values obtained with wild x wild zygotes of either age. The noncristate mitochondria were of two types: one lacking inner membrane invaginations or elaborations and the other containing concentrically arranged loops of inner membrane. The significance of these two types of respiration-deficient mitochondria is unknown. The gradual decrease in frequency of noncristate mitochondria, perhaps due to selection pressures in mixed chondriomes, was discussed as a further indication of the semiautonomous nature of the yeast organelle. PMID- 4293082 TI - Role of S-adenosylmethionine in methionine biosynthesis in yeast. AB - Extracts of Saccharomyces cerevisiae were used to develop a cell-free system capable of converting the beta-carbon of serine into the methyl group of methionine. No requirement for either S-adenosylmethionine or S adenosylhomocysteine could be demonstrated for net methionine biosynthesis. Growth of the cells in B(12) did not affect the reaction. The mechanism for the methylation of homocysteine in yeast appears to be similar to the non-B(12) system in Escherichia coli. PMID- 4293083 TI - Transfer of growth inhibition between normal and virus-transformed cells: autoradiographic studies using marked cells. PMID- 4293084 TI - Interaction between normal and transformed bovine fibroblasts in culture. I. Cells transformed by Rous sarcoma virus. PMID- 4293085 TI - QUuantitative investigation on the effect of puromycin on the aggregation of trypsin- and versene-dissociated chick fibroblast cells. PMID- 4293086 TI - Electron-microscopic studies on a double-stranded beaded filament of embryonic collagen. PMID- 4293087 TI - The production of 11-deoxycortisol (Reichstein's substance S) in patients with adrenocortical hyperfunction. PMID- 4293088 TI - Corticosteroid secretion in kangaroos (Macropus canguru major and M. (Megaleia) rufus). PMID- 4293089 TI - Some experiences with chemical inactivants of foot-and-mouth disease virus. PMID- 4293090 TI - Cumulative changes in the antigenic properties of herpes simplex virus from persistently infected cell cultures. PMID- 4293091 TI - Immunochemical studies of foot and mouth disease. I. Complement fixation reactions with isolated antigenic components. PMID- 4293092 TI - Effects of phenol solutions on the nerve roots of the cat: an electrophysiological and histological study. PMID- 4293093 TI - The cellular localization of mercury-203 chlormerodrin in astrocytomas. PMID- 4293094 TI - Kaposi's varicelliform eruption. PMID- 4293095 TI - Nephrotoxicity of antibiotics. PMID- 4293096 TI - [Diagnosis of tumors of the kidney in children]. PMID- 4293097 TI - Studies on silica shock in the rabbit. II. The possibility of release of "contact factor" by colloidal silica, and vasoconstriction of pulmonary embolism as the cause of death. PMID- 4293098 TI - [Immunological and histochemical research on popliteal lymph nodes of neonatal rabbits treated with antigens (diphtheria toxoid and ovalbumin) and adjuvants (tridymite and Freund's adjuvant)]. PMID- 4293099 TI - [Observations on the metabolic behavior in vitro of rabbit peritoneal polymorphonuclear cells in presence of silica particles]. PMID- 4293100 TI - Cellular age changes in insects. PMID- 4293101 TI - Changes in lipid metabolism with ageing. PMID- 4293103 TI - Replication of herpes simplex virus in arginine-free media. I. Effect of arginine deficiency in different tissue culture cells. PMID- 4293102 TI - The effect of ageing upon collagen metabolism. PMID- 4293104 TI - Replication of herpes simplex virus in arginine-free media. II. DNA synthesis in infected and non-infected human embryonic fibroblast and HeLa tissue culture cells. PMID- 4293105 TI - Phosphatidyl serine requirement of (Na+-K+)-activated adenosine triphosphatase from rat kidney and brain. PMID- 4293106 TI - The synthesis of taurocholic and glycocholic acids by preparations of human liver. II. An analysis of the stimulating effect of the L fraction. PMID- 4293107 TI - The anomeric configuration of L-rhamnose in uridine 5'-diphosphate rhamnose and thymidine 5'-diphosphate rhamnose. PMID- 4293108 TI - The synthesis of uridine diphosphate xylose by particulate preparations from mouse mast-cell tumors. PMID- 4293109 TI - The mechanism of the phosphoenolpyruvate synthase reaction. PMID- 4293110 TI - Electron spin resonance studies of the chloranil-cysteine, dichlone-cysteine and dichlone-glutathione reactions. PMID- 4293111 TI - A model for neuron firing with exponential decay of potential resulting in diffusion equations for probability density. PMID- 4293112 TI - [Distribution and evolution of free nucleotides of brain tissue in the rabbit during experimental atherosclerosis]. PMID- 4293113 TI - [Action of muscle-aldolase antiserum on aldolase of human hepatoma and of human fetal liver]. PMID- 4293114 TI - [Histochemical study of the mucus secreted by a malignant tumor of the colon cultured in vitro]. PMID- 4293115 TI - Determination of serum and plasma angiotensinase activity. PMID- 4293116 TI - Respiratory enzymes in mantle homogenates of Crassostrea virginica and the effects of Minchinia nelsoni (MSX), and Cochlodinium helicoides on activity levels. PMID- 4293117 TI - [The significance of bone scintigraphy for neurological diagnosis]. PMID- 4293118 TI - [Neurologic manifestations of sarcoidosis]. PMID- 4293119 TI - [Possible errors in the determination of metabolite concentrations in yeast cells]. PMID- 4293121 TI - Mechanisms of sympathetic regulation of arterial smooth muscle. PMID- 4293120 TI - Glutamic acid dehydrogenase activity in muscles of dystrophic mice. PMID- 4293122 TI - Serum desoxy-ribose compounds in experimental myocardial infarction. PMID- 4293123 TI - Effect of lidoflazine on norepinephrine, angiotensin and serotonin responses in isolated smooth muscle preparations. PMID- 4293124 TI - Histochemical nature of the motor endplate. PMID- 4293125 TI - Priming activity for RNA synthesis of chromatin from transplantable hepatomas and livers of tumor-bearing rats. PMID- 4293126 TI - Skin grafts in Donryu rats with and without acquired resistance to Yoshida sarcoma and ascites hepatomas. PMID- 4293127 TI - Biochemical changes in tumor cells caused by antitumor agents. 3. Further studies on the effects of antitumor agent on nad'ase and a few lysosomal enzymes of Yoshida sarcoma cells. PMID- 4293128 TI - Effect of pregnancy on growth of rat ascites tumors. PMID- 4293129 TI - The pharmacology of haloperidol. PMID- 4293130 TI - [Cyst-like tumors of the islands of Langerhans. Apropos of 2 cases]. PMID- 4293131 TI - [Subacute sclerosing leukoencephalitis, prolonged coticotherapy, severe chickenpox. Attempt at an interpretation of the edematous and necrosing character of the lesions]. PMID- 4293132 TI - The reactivity of the clotting mechanism and fibrinolysis in cerebral thrombotic disease. PMID- 4293133 TI - Potentiation of secretin stimulation of the pancreas. AB - 1. In fasted anaesthetized cats which were secreting pancreatic juice at a steady slow rate in response to continuous intravenous infusion of secretin, stimulation of the dorsal vagus trunk increased the rate of secretion, the rate of output of amylase and the concentration of bicarbonate in the juice.2. The increase in rate of secretion and in concentration of bicarbonate was reduced but not abolished by atropine. It was unaffected by adrenergic blocking agents, but abolished by hexamethonium.3. No increase in rate of secretion of secretin-stimulated juice was observed on cervical stimulation of vagus nerves in which the efferent fibres had degenerated after supra-nodose section of the nerves. It is concluded that the increase in secretion rate is mediated by ;atropine-resistant' efferent vagal fibres.4. Pancreozymin, antral extracts and histamine increased the rate of secretion of secretin-stimulated juice. Pancreozymin and antral extracts also increased the rate of amylase output. These effects of pancreozymin and antral extracts were not abolished by atropine or hexamethonium.5. As vagal stimulation pancreozymin, antral extracts and histamine have little or no effect on the resting pancreas of the anaesthetized cat, it is concluded that they exert a potentiating effect on secretin. It is suggested that the mechanism of this potentiation is an increase in pancreatic blood flow, which facilitates the supply of secretin to the gland. PMID- 4293134 TI - Responses of the pyramidal tract to stimulation of the baboon's motor cortex. AB - 1. The arm area of the baboon's precentral motor cortex was stimulated by brief surface-anodal pulses, and the discharge of the corticospinal tract (the ;pyramidal tract waves') was recorded by an electrode resting on the dorsolateral surface of the cervical spinal cord.2. Some properties of the pyramidal tract waves were described, and they were also studied in relation to the firing of single cortico spinal fibres.3. The results led to the conclusion that the later pyramidal tract waves (the ;I waves') were almost exclusively due to a semi synchronous repetitive discharge of the same fast cortico spinal fibres as those responsible for the initial wave (the ;D wave').4. Some problems concerning the origin and significance of the I waves were discussed. PMID- 4293135 TI - [Topographic and functional organization of the superior cervical ganglion in the rat]. PMID- 4293136 TI - "Pock-less" rabbit pox. PMID- 4293137 TI - Change in enzyme pattern after cross-innervation of fast and slow skeletal muscle. PMID- 4293138 TI - Dental abrasion and alveolar bone loss in the white rat. IV. The importance of the consistency of the diet and its abrasive components. PMID- 4293139 TI - Purification and physico-chemical characterization of Ecbovirus type SA-I. PMID- 4293140 TI - Muco-epidermoid carcinoma of the lacrimal gland. PMID- 4293141 TI - [Syncardon: treatment of chronic vascular disorders of the limbs]. PMID- 4293142 TI - [Management in the face of anemia in pregnancy]. PMID- 4293143 TI - The effect of 4,4'-methylenedianiline on adrenal corticosterone secretion in the rat. PMID- 4293144 TI - Quantitative analysis of the acquired resistance in tumor-bearing hosts. PMID- 4293145 TI - [Indications and results of cobalt teletherapy in the treatment of epithelial neoplasms of the oral cavity]. PMID- 4293146 TI - [Behavior of pulmonary radioactivity in patients exposed to endolymphatic radiotherapy with lipiodol F-I 131]. PMID- 4293147 TI - [Feedback-regulation of aspartate-transcarbamylase of various tissues]. PMID- 4293148 TI - [Purification and enzymatic characterization of the external membrane of mitochondria]. PMID- 4293149 TI - [Experimental study of the protective action of aerosols of aluminium compounds on fibrogenic lesions produced by quartz]. PMID- 4293150 TI - [Effects of corticostimuline and hydrocortisone on adrenaline secretion by the adrenal gland, in the hypophysectomized rat]. PMID- 4293151 TI - [New facts concerning the hormonal supervision of malignant trophoblastomas. Differentiations of the principal pituitary or chorionic gonadotropins in castrated subjects]. PMID- 4293152 TI - [Replication of polyoma virus on the kidney of a mouse inoculated at birth and on mouse embryo culture: electron microscopic study]. PMID- 4293153 TI - [Presence of cytochrome-oxidase positive Pseudomonas in Aedes]. PMID- 4293154 TI - [A contribution to the clinical aspects and morphology of diffuse temporal lobe blastoma, the so-called rhinencephalic spongioblastoma]. PMID- 4293155 TI - [On congenital mixed tumors of the cerebellum]. PMID- 4293157 TI - [On the epidemiology of the tumors of the central nervous system]. PMID- 4293156 TI - [The differential diagnostic significance of cerebral convulsion forms in temporal tumors]. PMID- 4293158 TI - Growth acceleration of a mouse cell line after infection with Friend leukemia virus. PMID- 4293159 TI - Evaluation of Sabin live poliovirus vaccine in Japan. II. Clinical, virologic and immunologic effects of vaccine in children. PMID- 4293160 TI - [Studies of the effect poliomyelitis live vaccine (Sabin) in small infants]. PMID- 4293161 TI - [Glomus tumors]. PMID- 4293162 TI - Humoral conditioning for necrosis. II. The challengers. PMID- 4293164 TI - [An electronic model for the formation of local and transmitted stimuli on the myocardium fibers based upon variable current-voltage characteristics for potassium and sodium ions]. PMID- 4293163 TI - [On the action of sugars, sugar alcohols and related substances on the fat mobilization]. PMID- 4293165 TI - [Electrophysiological correlation of Stevens power function and objective threshold measurement of the sensation of vibration in humans]. PMID- 4293166 TI - Auditory-evoked responses in cats with tenotomized middle ear muscles during sleep. PMID- 4293167 TI - [Electrolyte-and acid-base equilibrium in functional anomalies of the adrenal cortex]. PMID- 4293168 TI - [Effects of oxytocin on the syndromes of inappropriate antidiuretic hormone secretion, especially in cancer patients]. PMID- 4293169 TI - [Familial incidence of double malignancies]. PMID- 4293170 TI - [Effects of chronic renal failure on the endocrine glands]. PMID- 4293172 TI - [Active and passive homologous and heterologous interference experiements with Col. SK virus in mice]. PMID- 4293171 TI - [The influence of fibrinolysis inhibitors on the effect of bioactive substances on the guinea pig ileum. Studies on the problem of the effect of epsilon aminocaproic acid, acetyl-epsilon-aminocaproic acid and p-aminomethylbenzoic acid]. PMID- 4293173 TI - [Protective and control measures in imported smallpox epidemics]. PMID- 4293174 TI - [Embryonal sarcomas with craniofacial localization in children. (Radiological problems caused by paralysis at various levels of the cranial nerves in children]. PMID- 4293175 TI - [Gamma-encephalography in children. Preliminary results]. PMID- 4293176 TI - A method for assessment of skeletal maturity. PMID- 4293177 TI - [Human pathology caused by sheep udders]. PMID- 4293178 TI - [Histochemical studies on the dynamics of ACTH activity on the aortic wall tissue of white rats]. PMID- 4293179 TI - [Role of pituitary gland in diabetes mellitus]. PMID- 4293180 TI - [Electron microscopic findings on lung carcinoid]. PMID- 4293181 TI - [Case of non-functioning cancer of the islands of Langerhans with chronic diarrhea as a chief complaint]. PMID- 4293182 TI - [Transmission of stimulus in the heart]. PMID- 4293183 TI - [Testicular tumors in children]. PMID- 4293184 TI - The nutrition and metabolism of mycoplasma: Progress and problems. PMID- 4293185 TI - Electron spin resonance studies on heart muscle succinic dehydrogenase: substrate analogues. PMID- 4293186 TI - Biosynthesis of phytoene from isopentenyl and farnesyl pyrophosphates by a partially purified tomato enzyme system. PMID- 4293187 TI - Isolation and characterization of uridine diphosphate fructose from tubers of jerusalem artichoke (Helianthus tuberosus L.). PMID- 4293188 TI - Diphosphopyridine nucleotide-linked aldehyde dehydrogenase. 3. Sulfhydryl characteristics of the enzyme. PMID- 4293189 TI - Acetyl phosphatase in brain microsomes: a partial reaction of Na+ plus K+ ATPase. PMID- 4293190 TI - ESR and crystallization studies on iron-free xanthine oxidase. PMID- 4293191 TI - Gel filtration of nucleic acids on sphere-condensed agarose. PMID- 4293194 TI - Coexistence of infectious bronchitis and infectious laryngotracheitis. PMID- 4293192 TI - Vitamin D3-induced calcium-binding protein: partial purification, electrophoretic visualization, and tissue distribution. PMID- 4293193 TI - Studies on a 32S component of nuclear RNA. PMID- 4293195 TI - Mycoplasma gallisepticum in a commercial laryngotracheitis vaccine. PMID- 4293196 TI - The influence of co-precipitants on the solvent denaturation of double-stranded RNA. PMID- 4293197 TI - Interaction of glutamate dehydrogenase with fluorescent dyes. PMID- 4293198 TI - The binding of NADH by glutamate dehydrogenase as measured by polarization of fluorescence. PMID- 4293199 TI - [Changes in weight, protein content, RNA content, G-6-PDH activity and steroid content of the rat adrenal gland stimulated with ACTH. I. Results after short term stimulation]. PMID- 4293200 TI - [Changes in weight, protein content, RNA content, G-6-PDH activity and steroid content of the rat adrenal gland stimulated with ACTH. II. Results after prolonged stimulation]. PMID- 4293201 TI - [Vaccinia-antigen in relapsing herpes]. PMID- 4293203 TI - [Phosphofructokinase and fructose-1,6-diphosphatase activity in mouse liver after whole body irradiation]. PMID- 4293202 TI - An E.S.R. study of free radicals formed by reaction of nucleotides and their constituents with hydrogen atoms. PMID- 4293204 TI - Zonal increase in lactic dehydrogenase activity in the senescent human aorta. PMID- 4293205 TI - Low temperature magnetic susceptibility of ceruloplasmin. PMID- 4293206 TI - Ultracentrifuge and electron microscope studies on the structure of mitochondrial DNA. PMID- 4293208 TI - Electron microscope study of the denaturation of human papilloma virus DNA. I. Loss and reversal of supercoiling turns. PMID- 4293207 TI - Synthesis of low molecular weight ribonucleic acid in tumour cells. PMID- 4293209 TI - Electron microscope study of the denaturation of human papilloma virus DNA. II. The specific location of denatured regions. PMID- 4293210 TI - An adenovirus isolated from the feces of mice. II. Experimental infection. PMID- 4293211 TI - Serial passages of equine infectious anemia virus in horse leukocyte culture. PMID- 4293212 TI - Physicochemical studies on equine infectious anemia virus. Examination of purification methods. PMID- 4293214 TI - Propagation and titration of equine infectious anemia virus in horse leukocyte culture. PMID- 4293213 TI - Pathological studies on bone marrow in equine infectious anemia. I. Macroscopical findings on whole longitudinal sections of bone marrow. PMID- 4293215 TI - Half-lives of peptides and amines in the circulation. PMID- 4293216 TI - Interferon and the interaction of allogeneic normal and immune lymphocytes with L cells. PMID- 4293217 TI - Suppression of viral and chemical carcinogenesis by means of artificial heterogenization. PMID- 4293218 TI - Localization of lactic dehydrogenase isozymes in lysosomal fraction of the neutrophil of normal human blood. PMID- 4293219 TI - Hypsarrhythmoid EEG features in infants and young children with subdural hygromas. PMID- 4293220 TI - Chronic hemodialysis in "unselected" patients. PMID- 4293221 TI - Mechanisms of steatorrhea in the Zollinger-Ellison syndrome. PMID- 4293222 TI - Primary linitis plastica of the colon: report of a case and review of the literature. PMID- 4293223 TI - Adrenocortical responsiveness to ACTH and angiotensin II in hypophysectomized dogs and dogs treated with large doses of glucocorticoids. PMID- 4293224 TI - An effect of adrenocorticotrophic hormone on adrenal cholesterol accumulation. PMID- 4293225 TI - Effect of hypothalamic lesions on pituitary-adrenocortical responses to histamine and methopyrapone. PMID- 4293226 TI - Quantitative studies on the iodinated components secreted by the rat thyroid gland as determined by in situ perfusion. PMID- 4293227 TI - Application of the renin-antirenin assay in experimental hypertension: a preliminary report. PMID- 4293228 TI - Paramagnetic resonance spectrum of irradiated glycylglycine HCl. PMID- 4293230 TI - Gynandroblastoma of the ovary: review of 8 cases from the ovarian tumor registry. PMID- 4293229 TI - Changes of intestinal absorptive cells during maturation: an electron microscopic study of prenatal, postnatal, and adult guinea pig ileum. PMID- 4293231 TI - [Neuropathies, myopathies and neuromyopathies in chronic uremic patients]. PMID- 4293232 TI - [The diagnosis of hypoglycemia caused by malignant tumors]. PMID- 4293233 TI - Gradient centrifugation of viruses in colloidal silica. PMID- 4293234 TI - Studies on the synthesis of herpes simplex virions. PMID- 4293235 TI - Alkaline disruption of poliovirus: kinetics and purification of RNA-free particles. PMID- 4293236 TI - Isolation of an avian leukosis virus associated with the Harris strain of Rous sarcoma virus. PMID- 4293237 TI - Increased susceptibility to foot-and-mouth disease virus of bovine lung cells transformed by polyoma virus. PMID- 4293238 TI - Water vapor electrolysis. PMID- 4293239 TI - Photodynamic inactivation of Japanese encephalitis virus. PMID- 4293240 TI - Oxidative phosphorylation in crithidia fasciculata. PMID- 4293241 TI - The intracellular distribution of mercury in rat liver after methoxyethylmercury intoxication. PMID- 4293242 TI - Hepatic metabolism and enzyme activity in acute ethanol administration. PMID- 4293243 TI - Effects of actinomycin D and mitomycin C on the degradation of deoxyribonucleic acid and polydeoxyribonucleotide by deoxyribonucleases and venom phosphodiesterase. PMID- 4293244 TI - Equilibrium centrifugation of DNA, RNA, and poliovirus in density gradients of cesium oxalate and cesium acetate. PMID- 4293246 TI - A contagious pox disease in monkeys. PMID- 4293245 TI - [Contribution to the study of the active site of 3 (or 17)-beta-hydroxysteroid: NAD oxidoreductase of Pseudomonas testosteroni]. PMID- 4293248 TI - The sequence of elution of plant organic acids from silica gel chromatographic columns. PMID- 4293247 TI - Studies on cytochrome a. XVI. Significance of the molecular state of cytochrome a for oxidase activity. PMID- 4293249 TI - [On the chromatography of some 1-dimethylaminonaphthalene-5-sulfonyl derivatives on Kiesel gel G plates]. PMID- 4293250 TI - [High voltage paper iontophoretic separation and identification of 35S and 75Se labelled selenopolythionates]. PMID- 4293251 TI - A technique for the removal of the active silica gel layer from Eastman Chromagram sheet and its subsequent replication. PMID- 4293252 TI - Separation of polymyxin B, D, E and M by thin-layer chromatography. PMID- 4293253 TI - Studies on Rous sarcoma virus in mice. I. Establishment of an ascites sarcoma induced by the Schmidt-Ruppin strain of Rous sarcoma virus in C3H-He mouse. PMID- 4293254 TI - Viral ribonucleic acid of the Schmidt-Ruppin strain of Rous sarcoma virus. I. On the virus recovery from the medium of the in vitro cultivation of chicken wing web Rous sarcoma cells and the isolation of viral ribonucleic acid (RNA) from purified viral particles. PMID- 4293255 TI - Effects of alcohols and acetone on the neuromuscular junction of frog. PMID- 4293256 TI - New site of action of some narcotics, carbamate and alcohol on the respiratory enzyme system. PMID- 4293257 TI - Interlocked stresses in cartilage. PMID- 4293258 TI - Variation in physiological properties of crustacean motor synapses. PMID- 4293259 TI - Transmission from excitatory nerves to the smooth muscle cells of the rat seminal vesicles. PMID- 4293260 TI - Isolation of SV40 virus and its effect on renal function in African green monkeys. PMID- 4293261 TI - [Hepatomas in mice. I. Hepatomas in a strain of albino mice]. PMID- 4293262 TI - [Biochemical study of glucose-6-phosphatase and glucose-6-phosphate dehydrogenase activities in the bovine cornea]. PMID- 4293263 TI - Electron paramagnetic resonance of heme at intermediate oxidation states of cytochrome c oxidase. PMID- 4293264 TI - A virus released by "nonproducing" Rous sarcoma cells. PMID- 4293265 TI - Interaction among avian tumor viruses giving enhanced infectivity. PMID- 4293266 TI - Tumor virus RNA's. PMID- 4293267 TI - Symposium on RNA viruses and neoplasia. Comment. PMID- 4293268 TI - Infection of muscle cultures from various species with oncogenic DNA viruses (SV40 and polyoma). PMID- 4293269 TI - Follow-up study on corticotrophin treatment of multiple sclerosis. PMID- 4293270 TI - [Oxytocin-ACTH combination in the treatment of cerebral edema in vascular accidents and head injuries]. PMID- 4293271 TI - [Angiotensinases of human plasma]. PMID- 4293272 TI - An investigation of carriers of Entamoeba histolytica. PMID- 4293273 TI - Comparison of selected characteristics of four strains of infectious bovine rhinotracheitis virus. PMID- 4293274 TI - Infectious bovine rhinotracheitis-infectious pustular vulvovaginitis virus infection in pregnant cows. PMID- 4293275 TI - Antigenic analysis of bovine enteroviruses through studies of the kinetics of neutralization. PMID- 4293276 TI - Secretory rates of aldosterone in sodium-depleted calves. PMID- 4293277 TI - Cellular changes in the adrenal medulla of the calf following injection of adrenocorticotropic hormone and sodium depletion. PMID- 4293278 TI - Serologic study of reovirus infection in dogs. PMID- 4293279 TI - Development of an antigen in visceral lymphomatosis and splenic lymphoid foci. PMID- 4293280 TI - Histopathologic and hematologic changes in moribund stages of chicks infected with T-virus. PMID- 4293281 TI - Cytologic studies in polyoma virus-infected mouse embryo cells. PMID- 4293282 TI - Comparison of a bovine enterovirus and foot-and-mouth disease virus. PMID- 4293283 TI - Regrowth of primary cell cultures after infection with foot-and-mouth disease virus. PMID- 4293284 TI - Lyophilizing foot-and-mouth disease virus at low drying temperature. PMID- 4293285 TI - Cowpox and paravaccinia. PMID- 4293286 TI - Deaths associated with respiratory tract infection in childhood. PMID- 4293287 TI - Hypokalaemic alkalosis and hyperplasia of the juxtaglomerular apparatus without hypertension or oedema. PMID- 4293288 TI - Problem patients with vulvar malignancy. PMID- 4293289 TI - Gluconeogenesis during hibernation and arousal from hibernation. PMID- 4293290 TI - Heart excitatory and inhibitory substances in molluscan ganglia. PMID- 4293291 TI - Macrodactyly. PMID- 4293292 TI - Lipofibroma of the median nerve in the palm. PMID- 4293293 TI - Comparative study of histochemical patterns in non-neoplastic and neoplastic gastric epithelium: a study of Japanese in Hawaii. PMID- 4293295 TI - [Experimental observations on the action of crystalline silica on the possibility of macrophages transferring antigenic matter]. PMID- 4293294 TI - Triphosphoinositide phosphomonoesterase activity in nerve cellbodies, neuroglia and subcellular fractions from whole rat brain. PMID- 4293296 TI - Free radicals and their interactions in solid molecular mixtures. PMID- 4293297 TI - Electron spin resonance of two glycine peptides irradiated at 77 degrees K. PMID- 4293298 TI - [General problems of blisters of the buccal mucosa]. PMID- 4293299 TI - Hepatomas. PMID- 4293300 TI - [The effect of angiotensin on the renal elimination of sodium and potassium in arterial hypertension]. PMID- 4293301 TI - Getting on their nerves. PMID- 4293302 TI - Six cases of acrylamide poisoning. PMID- 4293303 TI - Development of tachyphylaxis to aspartyl and not asparginyl angiotensin II in the rat. PMID- 4293304 TI - Effects of an adrenal 11-beta, 17-alpha hydroxylase inhibitor in juvenile-onset diabetes mellitus. PMID- 4293305 TI - Studies on the mechanism of hormonal induction of the melanoblast-melanocyte transformation in organ culture. PMID- 4293306 TI - Muco-epidermoid metaplasia and argentaffin cells in nephroblastoma. PMID- 4293307 TI - Histamine-sensitising factor of Bordetella pertussis differentiated from immunogens by neutralisation and passive protection tests. PMID- 4293308 TI - Ultrastructural observations on the Harvey mouse leukaemia-sarcoma virus. PMID- 4293309 TI - Histo-enzymatic studies of experimental bacterial endocarditis. PMID- 4293310 TI - Phosphatase reaction of coagulase-negative staphylococci and micrococci. PMID- 4293312 TI - Evaluation of peripheral and central components of action of angiotensin on the sympathetic nervous system. PMID- 4293311 TI - Enzyme studies of the periosteum in experimental lathyrism. PMID- 4293313 TI - On the mechanism of ganglionic blockade by methacholine. PMID- 4293314 TI - Muscarinic transmission of preganglionic impulses to the adrenal medulla of the cat. PMID- 4293315 TI - On the mechanism of neuromuscular blocking action of bretylium and guanethidine. PMID- 4293316 TI - Rehabilitation of the stroke patient. PMID- 4293317 TI - Psychopharmacologic drugs. PMID- 4293318 TI - Diagnosis of abdominal masses. PMID- 4293319 TI - [Arterial hypertension of renal origin: abnormal secretion of renin]. PMID- 4293320 TI - Eruptive hidradenoma and syringoma. Histological, histochemical, and electron microscopic studies. PMID- 4293321 TI - Methotrexate. Effects on the enzymes of carbohydrate metabolism in psoriasis. PMID- 4293322 TI - Methylation of DNA in vitro: enzymic activity from different bacterial strains on DNA from various sources. PMID- 4293323 TI - Hepatocellular carcinoma in infancy and childhood in Ibadan, Western Nigeria. PMID- 4293324 TI - Metabolic degradation of 3,4-benzopyrene in the cultures of normal and neoplastic fibroblasts. PMID- 4293325 TI - Incidence of lung tumours in LX mice exposed to (1) free radicals; (2) SO2. PMID- 4293326 TI - [The adrenocorticotropic effect of synthetic beta 1-24 corticotropin]. PMID- 4293327 TI - [Endocrine disorders in pituitary tumors]. PMID- 4293329 TI - Electron spin resonance of irradiated DNA. PMID- 4293328 TI - [Islet cell tumor of the pancreas with intractable diarrhea]. PMID- 4293330 TI - Separation of chitin oligosaccharides by thin-layer chromatography. PMID- 4293331 TI - [Lymph node extensions of urogenital cancers in men (use of lymphography apropos of 73 cases)]. PMID- 4293332 TI - [A case of calcified nephroblastoma simulating a calculus]. PMID- 4293334 TI - [Attempted classification of Hodgkin's paragranuloma]. PMID- 4293333 TI - [The dependence of the efficacy of anabolic steroids on age and sex and their effects on the adrenal glands]. PMID- 4293335 TI - [Pseudo-tumoral retroperitoneal lymph node tuberculosis]. PMID- 4293336 TI - [Umbilico-portography]. PMID- 4293337 TI - [Right parasagittal abscess due to aspergillosis in a Negro, operated on with apparent cure]. PMID- 4293338 TI - [Spontanesou androgenic smears of mixed type. Apropos of 14 cases in young women]. PMID- 4293339 TI - [Plurisystemic degeneration of the neuraxis: new anatomoclinical contribution]. PMID- 4293341 TI - [Cerebro-meningeal cysticercosis. (Apropos of an anatomo-clinical case)]. PMID- 4293340 TI - [Dysgravidic histopathologic renal modifications during 1st trimester of normal pregnancy]. PMID- 4293342 TI - [Tolerance of pantothenic viomycin at a dosage of 1 gram per day]. PMID- 4293343 TI - [Mixed tumor of the laryngeal portion of the parotid gland, falsely diagnosed as a tuberculous jaw angle lymphoma]. PMID- 4293344 TI - [Bronchial mucoepidermoid tumors]. PMID- 4293345 TI - The effect of metyrapone on aldosterone secretion in man. PMID- 4293346 TI - Hormonal studies of a benign interstitial cell tumour of the testis producing androstenedione and testosterone. PMID- 4293347 TI - Chemical and electron microscopic studies of the black pigment of the human lung. PMID- 4293348 TI - Carcinoid syndrome associated with pancreatic tumors. PMID- 4293350 TI - Charcot-Marie-Tooth disease. PMID- 4293349 TI - Hyponatremia in acute polyneuropathy. Four cases with the syndrome of inappropriate secretion of antidiuretic hormone. PMID- 4293351 TI - Benign mucous gland adenoma of the bronchus. PMID- 4293352 TI - Inhalation therapy and postural drainage for the treatment of cystic fibrosis. PMID- 4293353 TI - Renal neoplasm in the newborn infant. PMID- 4293354 TI - Physiology of selenite reduction by enterococci. II. Characterization of selenite inhibition and its reversal by ascorbate. PMID- 4293355 TI - Further studies on the kinetic serum-neutralization (McBride) test for polioviruses. PMID- 4293356 TI - Cancer of the male breast: forty cases. PMID- 4293357 TI - [On the symptomatology of acute intermittent porphyria]. PMID- 4293358 TI - Factors affecting the production of foot-and-mouth disease virus in deep suspension cultures of BHK21 clone 13 cells. PMID- 4293359 TI - Serological studies on infections by respiratory viruses of the inhabitants of Tristan da Cunha. PMID- 4293361 TI - Neurosurgical experiences with herpes simplex encephalitis. PMID- 4293360 TI - The incidence of Herpesvirus hominis antibody in the population. PMID- 4293362 TI - Acute respiratory disease and meningococcal infection in army recruits. PMID- 4293363 TI - Vincristine sulfate in management of Wilms' tumor. Replacement of preoperative irradiation by chemotherapy. PMID- 4293364 TI - Testicular gas gangrene after hernia repair with cord division. PMID- 4293365 TI - Capillary-tube scanner for mechanized microbiology. A photoelectric scanner measures growth in agar-filled capillaries and gives a new approach to microbiology. AB - Growing microcolonies of bacteria can be detected by their light-scattering property. We have described a system in which growing bacteria in glass capillaries filled with nutrient agar are counted as the capillaries move through a narrow beam of light. Increased counts after incubation indicate the presence of viable organisms in the original sample; the equipment can detect colonies when they grow to a diameter of 8 microm. Aerobic, anaerobic, and facultative organisms can grow in the capillary environment. The sensitivities of several organisms to antibiotics were determined by adding antibiotics to the agar before the capillaries were filled. PMID- 4293366 TI - The ultrastructure of human mammary fibroadenoma. PMID- 4293367 TI - Copper distribution in the neonatal rat. PMID- 4293368 TI - Acidemia and catecholamine output of the isolated canine adrenal gland. PMID- 4293369 TI - Effects of angiotensin infusion on renal function in the unanesthetized rat. PMID- 4293370 TI - Iodized salt in the prevention of endemic goiter: a world-wide survey of present programs. PMID- 4293371 TI - Minimal infective dose of attenuated poliovirus for man. PMID- 4293372 TI - Inositide metabolism in rabbit hereditary ataxia. PMID- 4293373 TI - [Action of surface-active agents (Triton X 100, Osofor) and of an antimitotic drug (Daunomycin) on cells of ascites tumors]. PMID- 4293375 TI - Intraspinal tumors of infancy and childhood: a review of 19 surgically verified cases. PMID- 4293374 TI - Adrenocorticotrophic action of long-acting tetracosactrin compared with corticotrophin-gel. PMID- 4293376 TI - Morphological transformation of mouse embryo cells in vitro by murine sarcoma virus (Harvey). PMID- 4293377 TI - Labelled fluoroborate in the stomach of rats. PMID- 4293378 TI - Drugs and the Coombs antiglobulin test. PMID- 4293379 TI - Histochemistry of the periodontal ligament. II. The phosphatases. PMID- 4293380 TI - Clinical useful antimicrobial agents. General considerations concerning chloramphenicol, erythromycin and allied drugs, the polymyxins, bacitracin, vancomycin, ristocetin, cycloserine, the cephalosporins, the chemotherapeutic drugs and the antimycotic drugs. PMID- 4293381 TI - Clinically useful antimicrobial agents. Dosage and mode of administration. PMID- 4293382 TI - Clinically useful antimicrobial agents. Untoward reactions. PMID- 4293384 TI - Neuronal localization of dopamine and 5-hydroxytryptamine in some mollusca. PMID- 4293383 TI - [Pathological dyskinesia persisting during sleep]. PMID- 4293385 TI - Effect of ACTH on the metabolism of radioactive C-21 steroids by quartered rat adrenals. PMID- 4293386 TI - Experimental production of diarrhea and its prevention by Malethamer in monkeys. PMID- 4293387 TI - Inactivation of infectious bovine rhinotracheitis virus by calcium alginate wool swabs. PMID- 4293388 TI - A sensitive assay for egg-white and bacteriophage-induced lysozyme. PMID- 4293389 TI - Acceleration of cytochrome oxidase synthesis specific to zygotes from crosses between complementary respiratory deficient mutants of S. cerevisiae. PMID- 4293390 TI - The conversion of deoxyuridine 5'-monophosphate to deoxyuridine 5'-triphosphate in normal and regenerating rat liver. PMID- 4293391 TI - ACTH stimulation of adenyl cyclase in adrenal homogenates. PMID- 4293392 TI - Ferredoxin-activated fructose diphosphatase in isolated chloroplasts. PMID- 4293393 TI - Solubilization of enzyme forming ADPR polymer from NAD. PMID- 4293394 TI - Metabolism of lysine in rat liver. PMID- 4293395 TI - The structure of the serotype 2 capsular polysaccharide of Aerobacter aerogenes. PMID- 4293396 TI - Hydrolysis of dinucleoside monophosphates containing arabinose in various internucleotide linkages by exonuclease from the venom of Crotalus adamanteus. PMID- 4293397 TI - The isolation of skeletal muscle mitochondria showing tight coupling, high respiratory indices, and differential adenosine triphosphatase activities. PMID- 4293398 TI - Insulin-like action of ouabain. I. Effect on carbohydrate metabolism. PMID- 4293400 TI - [Research on the renal erythropoietic factor. II. Erythropoietic activity in rats treated with val-5-angiotensin]. PMID- 4293399 TI - Insulin-like action of ouabain. II. Primary antilipolytic effect through inhibition of adenyl cyclase. PMID- 4293401 TI - [Influence of imipramine on curarism. I]. PMID- 4293402 TI - [Influence of imipramine on curarism. II]. PMID- 4293403 TI - Adrenolytic and sympatholytic properties of 2-halogenoalkylamines in the vas deferens of the guinea-pig. PMID- 4293404 TI - [Phospholipid metabolism in rabbit erythrocytes. I. In vivo incorporation of P32 into erythrocyte phospholipids]. PMID- 4293405 TI - Presence of corticotropin activity in the pituitary gland of chondrichthyean fish. PMID- 4293407 TI - An improved technique for radial nerve conduction studies. PMID- 4293406 TI - Pituitary corticotrophin reserve and endocrine function in the syndrome of pituitary adenoma with galactorrhea. PMID- 4293408 TI - Granulomatous meningitis and diffuse parenchymatous degeneration of the nervous system due to an intracranial epidermoid cyst. PMID- 4293409 TI - Membrane impedance changes during synaptic transmission in cat spinal motoneurons. PMID- 4293410 TI - Dendritic location of synapses and possible mechanisms for the monosynaptic EPSP in motoneurons. PMID- 4293411 TI - Presynaptic inhibition induced by vagal afferent volleys. PMID- 4293412 TI - Evaluation of Sabin live poliovirus vaccine in Japan. 3. Studies on the method of administration of Sabin vaccine for babies. PMID- 4293413 TI - Evaluation of Sabin live poliovirus vaccine in Japan. IV. Marker tests on poliovirus strains recovered from vaccinees and their contacts. PMID- 4293414 TI - Immunofluorescent study on the pathogenesis of oral infection of poliovirus in monkeys. PMID- 4293415 TI - New vasoconstrictor, bovine peptide-B, released during blood coagulation. PMID- 4293416 TI - Action of Sendai virus and neuraminidase on the alkaline phosphatase isoenzymes of HeLa cells. PMID- 4293417 TI - Protein components of encephalomyocarditis virus. PMID- 4293418 TI - Changes in nucleic acid metabolism of tumour cells under high pressure oxygen. PMID- 4293419 TI - Carcinogenicity of the herbicide maleic hydrazide. PMID- 4293420 TI - Hypothalamic and extrahypothalamic mechanisms controlling adrenocorticotrophin secretion. PMID- 4293421 TI - Hypothalamic control of concomitant secretion of ACTH and TSH. PMID- 4293422 TI - Excitation and inhibition of ACTH secretion. PMID- 4293423 TI - Anatomical and functional mapping of central neural input and feedback pathways of the adrenocortical system. PMID- 4293424 TI - The influence of corticosteroids on the stress-induced release of corticotrophin. PMID- 4293425 TI - A study of compensatory adrenal hypertrophy and hyperfunction. PMID- 4293426 TI - Control of adrenal precursors of urinary 17-oxosteroids. PMID- 4293427 TI - Adrenocorticotrophic activity of synthetic peptide sequences related to ACTH. PMID- 4293428 TI - Some observations on the control of cortisol secretion in man. PMID- 4293429 TI - Assessment of pituitary-adrenal function in children. PMID- 4293430 TI - The effects of prolonged ACTH or corticosteroid therapy in children on growth and on pituitary-adrenal and pituitary function. PMID- 4293431 TI - The action of histamine, 5-hydroxytryptamine, and blockers upon the 86rubidium kinetics of rat erythrocytes. PMID- 4293432 TI - Pathological lesions associated with Schistosoma mansoni infection in man. PMID- 4293433 TI - Enteroviruses in a Trinidad nursery. PMID- 4293434 TI - [The mechanism of the inhibitory action of reserpine against morphine]. PMID- 4293436 TI - [On the production of monovalent foot-and-mouth disease vaccine concentrate from tissue culture virus type O]. PMID- 4293435 TI - [Trials of vaccination ff swine against foot-and-mouth disease virus type O with a live vaccine obtained through mouse brain passage]. PMID- 4293437 TI - [Cultivation of foot-and-mouth disease virus type O in tissue cultures and utilization of its mutability for the production of new vaccine strains]. PMID- 4293438 TI - [On the surgery of diffuse glomus tumors in the region of the foramen jugulare]. PMID- 4293440 TI - Transformation induced by SV40 in various types of mammalian cell cultures. I. Transformation in cultures of human embryonic cells. PMID- 4293441 TI - Transformation induced by SV40 in various types of mammalian cell cultures. II. Transformation in hamster, rabbit and mouse kidney cell cultures. PMID- 4293439 TI - [Studies concerning sensitivization to the toxins of Cl. oedematiens, Cl. perfringens and C. diphtheriae of antipertussis-vaccinated mice]. PMID- 4293442 TI - Thermodependence of the growth of attenuated type 1 poliovirus in MS cells. PMID- 4293443 TI - [Contribution to the study of the methods of isolation of Cl. perfringens. VI. Rapid method for the identification of Cl. perfringens]. PMID- 4293444 TI - [Immuno-epidemiologic study of adenovirus infections in Rumania]. PMID- 4293445 TI - [Callous and silicified emergence of Selaginella leaves]. PMID- 4293446 TI - [Pituitary-interrenal axis and osmoregulation in the salt water eel. Study of the intact animal with notes on disturbances of the mineral balance produced by the effect of "shock"]. PMID- 4293447 TI - [Protection of deoxyribonucleic acid by cystamine in the photomutagenic effect]. PMID- 4293448 TI - [Changes in arylesterase-lipase, phosphatase and beta-glucuronidase activities in the ovaries of puberal female rats, treated comparatively with ethinyl estradiol and lynestrenol]. PMID- 4293449 TI - [Vascular reactions to angiotensin and vasomotor tonus]. PMID- 4293450 TI - [Influence of angiotensin on cardiac output in shock]. PMID- 4293452 TI - [The inactivation of enteroviruses in water by hydrogen peroxide]. PMID- 4293453 TI - [The multiplication and toxin formation of Cl. perfringens in food products]. PMID- 4293451 TI - [The 7/sec-wave in the brain current picture of the adult]. PMID- 4293454 TI - [On the malignant tumors of the urogenital system]. PMID- 4293455 TI - [Diagnosis and treatment of salivary gland tumors]. PMID- 4293456 TI - [Scheme for extraction and quantitative fractionation of lipids from liver and hepatomas]. PMID- 4293457 TI - [Origin and treatment of sinusitis in children]. PMID- 4293458 TI - [Changes in the production and metabolism of cortisol in healthy infants after 3 days of administration of depot-ACTH. II. Urinary elimination of the preliminary stage metabolites pregnane-3-alpha-17-alpha-20-alpha-triol and pregnane-3-alpha 20-alpha-diol]. PMID- 4293459 TI - [The modification of plaque formation in modified and non-modified foot-and-mouth disease virus by polyions and methyl cellulose]. PMID- 4293460 TI - [On the virucidal effect of currant juice]. PMID- 4293461 TI - Prevention of delayed traumatic facial palsy. PMID- 4293462 TI - [Methods for the determination of the age of the femur]. PMID- 4293463 TI - Ultrastructural variations of nuclear bodies in human diseases. PMID- 4293464 TI - Some observations on the ultrastructure of a malignant islet cell tumor associated with duodenal ulceration and severe diarrhea. PMID- 4293465 TI - Nuclear bodies: a component of cell nuclei in hamster tissues and human tumors. PMID- 4293466 TI - A glycogen body in liver nuclei. PMID- 4293467 TI - [Granuloma gangraenescens of the nose]. PMID- 4293468 TI - [Apropos of a hydromyelia and acromegaly association in the same patient]. PMID- 4293469 TI - Comparison of different long-acting corticotropin preparations in the two-day corticotropin test in man. PMID- 4293470 TI - Quantitative in vitro studies on noradrenaline uptake and its inhibition by amphetamine, desipramine and chlorpromazine. PMID- 4293471 TI - Sympathetic control of rhythmically active vascular smooth muscle as studied by a nerve-muscle preparation of portal vein. PMID- 4293472 TI - Spread of excitation in the smooth muscle of the rat portal vein. PMID- 4293473 TI - The effect of DOPA on the spinal cord. 5. Reciprocal organization of pathways transmitting excitatory action to alpha motoneurones of flexors and extensors. PMID- 4293474 TI - The effect of DOPA on the spinal cord. 7. Reflex activation of static gamma motoneurones from the flexor reflex afferents. PMID- 4293475 TI - Quantitative studies on the transmitter release at adrenergic nerve endings. PMID- 4293476 TI - [The glycolytic system in a hemolysate of human erythrocytes]. PMID- 4293478 TI - [A case of spinal cord glioblastoma]. PMID- 4293477 TI - Dust exposure in mechanical street sweepers. PMID- 4293479 TI - [Study of the distribution of inositol in the cortex and nucleus of the calf lens]. PMID- 4293480 TI - [On primary damage of autonomic ganglia following infection with Herpes suis virus in different animal species]. PMID- 4293481 TI - Demethylimipramine (desipramine), an alpha-adrenergic blocking agent. PMID- 4293482 TI - The effect of lithium ions on the post-tetanic potentiation of neuro-muscular transmission. PMID- 4293483 TI - Comparative effects of carbon tetrachloride and colchicine on xanthine dehydrogenase. PMID- 4293484 TI - The role of pyrophosphate and alkaline phosphatase in skin calcification (calciphylaxis). PMID- 4293485 TI - [Effect of bovine serum albumin on K-ion-dependent p-nitropheynlphosphatase]. PMID- 4293486 TI - [Studies on detoxication of diphtheria toxin by adrenal and pituitary hormones. (1). Effects on the lethal dose of diphtheria toxin]. PMID- 4293487 TI - [Studies on detoxication of diphteria toxin by adrenal and pituitary hormones. (2). Effects on the paralytic dose of diphtheria toxin]. PMID- 4293488 TI - [On clinical features of synovial sarcoma]. PMID- 4293489 TI - Relationship between DNA synthesis and cell density in normal and virus transformed cells. PMID- 4293490 TI - Structural and metabolic distinction between Morris hepatoma 5123 A and normal rat liver. PMID- 4293491 TI - Tumour-specific antigenicity of aminoazo-dye-induced rat hepatomas. PMID- 4293492 TI - Hysterosalpingography and pelvic arteriography in postoperative follow-up of hydatidiform mole. PMID- 4293493 TI - Histochemical studies on two types of alpha-glycerophosphate dehydrogenase in human cervical cancer. PMID- 4293494 TI - Fluorinated pyrimidines. XXIX. Syntheses of 2',3'-dehydro-5-fluoro-2' deoxyuridine and 2',3'-dideoxy-5-fluorouridine. PMID- 4293495 TI - Synthesis and amebicidal activities of some 1',2'-secoemetine derivatives. PMID- 4293496 TI - 2,2'-hydrazobis(5-nitrothiazoles) and analogs, a new type of antiprotozoal agents. PMID- 4293497 TI - Photochemical degradation of flavins. IV. Studies of the anaerobic photolysis of riboflavin. PMID- 4293498 TI - [2 cases of Bard's syndrome (miliary metastases of gastric cancer to the lungs)]. PMID- 4293499 TI - [General round table discussion on enzymology]. PMID- 4293500 TI - [A consequence of the progress of hygiene. The marked and progressive rareness of pathogenic microorganisms responsible for infections by indirect transmission]. PMID- 4293501 TI - [Drug allergy to ACTH: its clinical manifestations; means for its prevention]. PMID- 4293502 TI - [Microbial jaundice]. PMID- 4293503 TI - l,l-dimethylhydrazine-induced diuresis. PMID- 4293504 TI - Effect of incubation temperature on enzyme production for lysine decarboxylase and cytochrome oxidase tests. PMID- 4293505 TI - The suprarenal cortical function as measured by the plasma 17 hydroxycorticosteroid level in malnourished children. I. PMID- 4293506 TI - [Hemagglutinin inhibition titers of Japanese B encephalitis in man, mammals and birds]. PMID- 4293507 TI - [Study of the mastocyte component and eosinophils in histiocytomas and in xanthomas]. PMID- 4293508 TI - [Study of the cutaneous phosphatase activity in products of conception that have enjoyed a minimum of extrauterine life]. PMID- 4293509 TI - Thermostable Clostridium perfringens as the cause of a food poisoning outbreak. PMID- 4293510 TI - Hormonal influences and salt restriction. PMID- 4293511 TI - [Primary malignant myoma of the pulmonary artery]. PMID- 4293512 TI - [Repeated operative procedures on stomach cancer]. PMID- 4293513 TI - [Angioleiomyoma of the skin]. PMID- 4293514 TI - Hospital and community. PMID- 4293515 TI - [Comparative neuromuscular actions of venoms from 3 species of Naja (N. haje, N. nigricollis and N. naja)]. PMID- 4293516 TI - Release of a renin-like enzyme from the pregnant uterus of the rabbit. PMID- 4293517 TI - Purification and properties of methionyl-transfer-ribonucleic acid synthetase from Escherichia coli. AB - 1. Methionyl-t-RNA synthetase (where t-RNA denotes ;soluble' or transfer RNA) has been purified to apparent homogeneity from a ribonuclease I-free strain of Escherichia coli. Polyacrylamide-gel electrophoresis of the final product revealed a single band. The purified enzyme catalyses the exchange of 450mumoles of pyrophosphate into ATP/mg. in 15min. at 37 degrees . 2. Methionyl-t-RNA synthetase is specific for the l-isomer of methionine, but appears to catalyse the methionylation of two distinct species of t-RNA, both of which are specific for methionine, but only one of which may be subsequently formylated. 3. The Michaelis constant for l-methionine is 2x10(-4)m in the ATP-PP(i) exchange assay and 2x10(-5)m for the acylation of t-RNA. 4. Gel filtration of both crude and highly purified preparations of methionyl-t-RNA synthetase on Sephadex G-200 indicates that the active species of enzyme has a molecular weight of about 190000. The amino acid composition of the enzyme is similar to those reported for the isoleucine and tyrosine enzymes from E. coli. PMID- 4293518 TI - [Spleno-endocrine correlations. I. Histological and weight changes of the spleen in ovariectomizied rats treated with several pituitary trophic hormones]. PMID- 4293519 TI - [Studies of hypoxia. II. Pressor behavior and pressor response to nor-adrenaline, pitressin, hypertensin, isoprenaline and acetylcholine in hypoxia caused by decreased pulmonary ventilation]. PMID- 4293520 TI - Fluorometric determinations of NADH2 levels in dorsal root ganglion following peripheral nerve stimulation. PMID- 4293521 TI - [Purification of muscle acylphosphatase of chicken breast]. PMID- 4293522 TI - [Enzymic and nonenzymic oxidation of reduced diphosphopyridine nucleotide in the presence of L-ascorbic acid]. PMID- 4293523 TI - Synovioma: review of the literature with case reports. PMID- 4293524 TI - Isolation and characterization of alkaloids from Caulophyllum thalictroides. PMID- 4293526 TI - Segregation kinetics of particulate solids systems. IV. Effect of particle shape on energy requirements. PMID- 4293525 TI - Grayanotoxin. I. Occurrence in additional Ericaceae species. PMID- 4293527 TI - Hormones and the RES. PMID- 4293528 TI - [Intrahepatic angiography and cholangiography in liver and bile duct tumors]. PMID- 4293529 TI - On the conservative treatment of severe ischemia of the leg. PMID- 4293530 TI - [The level of oxypurines in the plasma and urine of control and gout patients. (Correlation with the level of uric acid)]. PMID- 4293531 TI - [Treatment of hyperuricemic and gouty patients with derivatives of benzofuran]. PMID- 4293532 TI - [Determination of the arthrogenic effect in rats of a peptide glycolipid fraction from D type wax administered in the form of Freund's adjuvant]. PMID- 4293533 TI - [The 19-norsteroids in the treatment of periodic disease]. PMID- 4293534 TI - [Urinary lithiasis with hypertension. Statistical study of 34 cases]. PMID- 4293535 TI - [What is the status of the oral treatment of diabetes?]. PMID- 4293536 TI - [Televised endoscopy in black and white and color]. PMID- 4293537 TI - [Ulcerative mutilating acropathy. Possible role of the tarsal tunnel]. PMID- 4293538 TI - [Surgical treatment of angiomas of the parotid region]. PMID- 4293539 TI - [Enzyme-histochemical studies on rat liver after untreated and treated CCl4 poisoning]. PMID- 4293540 TI - Comparative sequence studies of rat skin and tendon collagen. I. Evidence for incomplete hydroxylation of individual prolyl residues in the normal proteins. PMID- 4293541 TI - Limited trypsin-catalyzed hydrolysis of crystalline human ceruloplasmin. Partial characterization of the digest. PMID- 4293542 TI - Diphosphopyridine nucleotide specific isocitric dehydrogenase of mammalian mitochondria. II. Kinetic properties of the enzyme of the Ehrlich ascites carcinoma. PMID- 4293543 TI - Flavin-pyridinium biscoenzyme analogs. Synthesis and reactivity. PMID- 4293544 TI - Cholinergic mechanisms in the release of catecholamines from intra-ganglionic inhibitory terminals? PMID- 4293547 TI - [Studies on Clostridium welchii in the feces of healthy human. 2. Distribution of Hobbs' type of the organism]. PMID- 4293545 TI - Production of antibodies against synthetic angiotensin II in various animal species. PMID- 4293546 TI - The substrate supply of the human skeletal muscle at rest, during and after work. PMID- 4293549 TI - [On the effect of an ovulation inhibitor on plasma steroids]. PMID- 4293551 TI - [Treatment of Blitz-Nick-Salaam convulsions with Mogadan]. PMID- 4293548 TI - [On the mechanism of accelerated Na excretion during i.v. administration of highly hypertonic NaCl solutions in patients with essential hypertension. II. Tubular factors. Presumed functional relationships]. PMID- 4293550 TI - [Succinate dehydrogenase and cytochrome oxidase activity in homogenates and mitochondrial fractions of brain tumors and non-neoplastic brain tissue]. PMID- 4293552 TI - [Neural autoplasty. Experiences with 118 patients with injuries of the peripheral nerves]. PMID- 4293553 TI - [Experimental formation of talc and magnesite from serpentin and carbon dioxide]. PMID- 4293554 TI - [Competitive inhibitors of nitrate reduction by xanthine oxidase]. PMID- 4293555 TI - [Effect of DL-palmitoyl carnitine on rat heart mitochondria]. PMID- 4293556 TI - [Psychoses and brain tumors. A casuistic contribution to the psychiatry of brain tumors]. PMID- 4293557 TI - [Cerebrospinal fluid cytology in the course of treated mumps encephalitis in children]. PMID- 4293558 TI - [The effect of penetrating radiation on the cytochrome oxidase of the small intestine of the mouse]. PMID- 4293559 TI - [Clinical aspects of pneumonia in parainfluenza in adults]. PMID- 4293560 TI - [Immediate and remote results of the surgical treatment of hypoglycemia]. PMID- 4293561 TI - [Intrathoracic chemodectoma (non-chromaffin paraganglioma)]. PMID- 4293562 TI - [Changes in the karyotype of human cells in vitro induced by simian virus 40]. PMID- 4293563 TI - [Cytophotometric analysis of some methods of selective RNA extraction from nervous tissue sections]. PMID- 4293564 TI - [Treatment of cow udder pox with ultrasonics]. PMID- 4293566 TI - [The behaviour of human complement in bronchial asthma]. PMID- 4293565 TI - [Histophysiology of the adenophypophysis of the newt (Triturus cristatus carnifex Laur.)]. PMID- 4293567 TI - [On the classification of Actinomyces vinaceus]. PMID- 4293568 TI - [The effect of D-cycloserin and florimycin on the activity of glutamate aspartate transaminase in blood serum of albino mice]. PMID- 4293569 TI - [Effect of oleandomycin phosphate on secretory and enzymatic functions of the intestine]. PMID- 4293570 TI - [Unsolved histopathologic problems related to cystosarcoma phylloides of the breast]. PMID- 4293571 TI - [On the comparative assessment of the coniosis hazards of industrial dust]. PMID- 4293572 TI - Electron microscopic observations on the sites of activities of succinic dehydrogenase and cytochrome oxidase in Mycobacterium tuberculosis and Bacillus megaterium. PMID- 4293573 TI - [Primary malignant tumors of the breast]. PMID- 4293574 TI - [Experience with clinical use of cyclophosphane]. PMID- 4293576 TI - [On diagnostic and prognostic importance of the reaction of gastric juice in stomach carcinoma]. PMID- 4293575 TI - [Radicality and pathophysiological aspects in the resection of stomach carcinoma]. PMID- 4293577 TI - [Anatomopathologic contribution to the definition of a common pathogenesis of pneumoconiosis induced by organic silica (tripoli and diatoms)]. PMID- 4293578 TI - [Organic hyperinsulinism, diagnosis and therapy]. PMID- 4293579 TI - The negative chronotropic effect of adenine derivatives and acetylcholine on frog and rat hearts. PMID- 4293580 TI - [Therapeutic indications in peripheral facial paralysis]. PMID- 4293581 TI - [The resistance of hog enterovirus strain T80 to disinfectants]. PMID- 4293582 TI - [Neuroectodermal brain tumors as the cause of death in newborns and infants]. PMID- 4293584 TI - Zollinger-Ellison syndrome. PMID- 4293583 TI - [The effect of virus infections on the course of cell division]. PMID- 4293585 TI - Differential studies of angiotensinase activities from several tissue sources. PMID- 4293586 TI - Effect of cyanide and Antimycin A on the reduction of cytochrome b and ubiquinone in electron transport particles. PMID- 4293587 TI - Rate of reduction of ubiquinone by NADH in electron transport particles. PMID- 4293588 TI - Carrier-free zone electrophoresis of infectious ribonucleic acid derived by phenol and sodium dodecylsulfate methods from purified foot-andmouth disease virus. PMID- 4293589 TI - Energy-linked reactions in photosynthetic bacteria. I. Succinatelinked ATP-driven NAD reduction by Rhodospirillum rubrum chromatophores. PMID- 4293590 TI - Interaction of dimethyl-p-phenylenediamine with ceruloplasmin. PMID- 4293591 TI - Studies on acellular bovine glomeruli. Isolation, chemical composition, and demonstration of collagen with an unusual hydroxylysine: hydroxyproline ratio. PMID- 4293592 TI - [On the histotopy of several oxidative and hydrolytic enzymes in basalioma]. PMID- 4293593 TI - [The sensitivity of Neisseria gonorrhoeae and other species of the Neisseria towards antibiotics]. PMID- 4293594 TI - [Therapy of sarcoidosis]. PMID- 4293595 TI - [Contribution on the occurrence and form of congenital hand deformities]. PMID- 4293596 TI - Growth hormone deficiencies in childhood. PMID- 4293597 TI - Survival after bilateral adrenal hemorrhage during heparin therapy. PMID- 4293598 TI - [Alveolar cell carcinoma. A report of cases with review of literature]. PMID- 4293599 TI - The specificity of silica cytotoxicity. A study in vitro. PMID- 4293600 TI - [The metabolism of macrophages after phagocytosis of silica dust]. PMID- 4293601 TI - Influence of acute and chronic administration of alcohol on carbohydrate breakdown and energy metabolism in the liver. PMID- 4293602 TI - In vivo interaction of 4-nitroquinoline-1-oxide and its derivatives with DNA. PMID- 4293603 TI - [Pemphigus and pemphigoid. Course and treatment of 35 cases]. PMID- 4293604 TI - [Tongue changes in lesions of the hypoglossal nerve]. PMID- 4293605 TI - [Modifications induced by the corticotropic hormone in spleen structure]. PMID- 4293606 TI - [Neoplasms of the penis. II. Anatomo-pathologic features and macroscopic development studies on 68 cases]. PMID- 4293607 TI - [On a case of giant tumor of the breast]. PMID- 4293608 TI - [Functional exploration of the adrenal gland in subjects with pulmonary tuberculosis; effects of hypoglycemia induced with ACTH]. PMID- 4293610 TI - Thin layer chromatography of substituted nitroanilines and related compounds. PMID- 4293609 TI - Determination of castor oil in heveacrumb rubber by thin-layer chromatography. PMID- 4293611 TI - [Separation of oligonucleotides of apurinic DNS by two-dimensional thin layer chromatography on silica gel]. PMID- 4293612 TI - [Solanum alkaloids. 83. Analytical and preparative thin layer chromatographic separation of 5alpha-saturated and respectively delta5-unsaturated steroid alkaloids and -sapogenins in silver nitrate rich absorption plates]. PMID- 4293614 TI - Chromatoplate contamination removal. PMID- 4293613 TI - An ultrasensitive chemical test for quantitative chromatography of sugars. PMID- 4293615 TI - Thin-layer chromatography of n-(p-toluenesulfonyl)-carbamates. PMID- 4293616 TI - Thin-layer chromatographic separation of benefin and related substances. PMID- 4293617 TI - The quantitative separation of porphyrins and protohaemin as methyl esters by thin-layer chromatography. PMID- 4293618 TI - Thin-layer chromatography of the peyote alkaloids. PMID- 4293619 TI - [Demonstration of cytochrome oxidase with the aid of polyacrylamide electrophoresis]. PMID- 4293620 TI - Thin-layer chromatography of vitamin A metabolites in human serum and liver tissue. PMID- 4293621 TI - Paper and thin-layer electrophoretic separations of polynuclear aza heterocyclic compounds. PMID- 4293622 TI - Chromatographic separation of 2,4-dinitro-5-aminophenyl derivatives of amino acids. PMID- 4293623 TI - The identification of colistin and polymyxin B by thin-layer chromatography. PMID- 4293624 TI - [Clinical aspects of Japanese encephalitis in the aged]. PMID- 4293625 TI - Interaction of phospholipid-metal complexes with water-soluble wheat protein. AB - Insoluble lipid-protein complexes are formed in the presence of Ni(II), Ca(II), or Mg(II) by specific components of the water-soluble proteins of wheat flour and either triphosphoinositide or phosphatidyl serine. The pattern of protein species bound by the lipid-metal complex is dependent upon the metal and the phospholipid used. A group of proteins, containing carbohydrate, may be solubilized and recovered by washing the precipitate with acidic chloroform-methanol-water. Analyses of reactive and nonreactive protein species have shown no differences which clearly account for their behavior. Methylation of protein increases binding to lipid; acetylation decreases the interaction. Weak interaction has been observed between certain components of flour proteins and phospholipid in the absence of metal ions, but the components differ from those bound in the presence of metal ions. It is suggested that properly oriented groups of the protein molecules are chelating onto available coordination positions of metal ions already bound to phospholipid. PMID- 4293626 TI - Increase in cell lipid and cytoplasmic particles in mammalian cells cultured at reduced pH. AB - The hydrogen ion concentration of the medium has been shown to exert a regulatory effect on the lipid content of cultured mammalian cells. Reduction of the pH of the medium from 7.4 to 6.9 causes a significant increase in cell lipid, relative to cell protein, within 2-3 days. Triglycerides are increased twofold and account for 75% of the additional lipid. Polar lipids, on the other hand, remain nearly constant in concentration. Concurrent with the increase in lipid, particles with an average diameter of 1 micro appear in the cytoplasm. Because the density of these particles is low, ultracentrifugation of the cell homogenate separates the particles completely from the other subcellular structures. The amount of lipid in the particle fraction is approximately equal to the increase in total cell lipid. As shown by silicic acid column chromatography, the particle lipid contains about 75% triglycerides, 15% diglycerides plus an unknown substance, and smaller amounts of material in the monoglyceride and sterol ester-hydrocarbon fractions. The quantitative results indicate that the lipid accumulated at low pH is assembled into discrete cytoplasmic particles. PMID- 4293627 TI - [The renin-angiotensin system. Current biochemical and physiopathological problems]. PMID- 4293628 TI - Lofland HB: Biological activities of vitamins D2 and D3 for growing squirrel monkeys. PMID- 4293629 TI - Intracranial tumours in rats injected intracerebrally with murine sarcoma virus (MSV), Moloney's strain. Preliminary report. PMID- 4293630 TI - [Chemodectoma of the middle ear (Tumor of the jugular and tympanic glomus)]. PMID- 4293631 TI - Activity of cytochrome C oxidase and succindehydrogenase in the lungs in experimental silicosis. I. Early stages. PMID- 4293632 TI - [Clinico-radiological findings on the incidence of pneumoconiosis in workers engaged in the manufacture of carbon electrodes]. PMID- 4293633 TI - [Blood volume and erythrocyte count. On the evaluation of hematological diseases]. PMID- 4293634 TI - [The functional status of the adrenal glands in children under hormone therapy for diffuse glomerulonephritis]. PMID- 4293635 TI - [Tests on clinical and biological symptoms leading to the diagnosis of Langerhans adenoma]. PMID- 4293636 TI - [Methods of transmission in the specific thalamic nuclei during deep sleep]. PMID- 4293637 TI - [The behavior of serum-cholesterins in patients with multiple sclerosis]. PMID- 4293638 TI - [Tuberculostatics of the second order (relay drugs). Their share in combined therapy of pulmonary tuberculosis]. PMID- 4293639 TI - [Initial inhibiting action of glucose on incorporation of glycine-2-C 14 into the proteins of hepatoma cells]. PMID- 4293640 TI - [Cycles of swelling and contraction of slight degree in rat liver mitochondria and mitochondria of Yoshida ascites hepatoma]. PMID- 4293641 TI - The measurement of 3beta-hydroxy-delta5 steroids in human fetal blood, amniotic fluid, infant urine and adult urine. PMID- 4293642 TI - [On unusual benign lung tumors]. PMID- 4293643 TI - [Primary malignant tumors of the pericardium]. PMID- 4293644 TI - Respiratory virus vaccines. VII. Field evaluation of respiratory syncytial, parainfluenza 1, 2, 3, and Mycoplasma pneumoniae vaccines, 1965 to 1966. PMID- 4293645 TI - Intrapulmonary chemodectomas in subjects with organizing pulmonary thromboemboli. PMID- 4293646 TI - Micro methods for the quantitative determination of iron and copper in biological material. PMID- 4293648 TI - Identification of the polymyxins. PMID- 4293647 TI - Neomycin-polymyxin prophylaxis of urinary-tract infection associated with indwelling catheters. PMID- 4293649 TI - Antigonadotropic hormones and lipogenesis in the testis and seminal vesicles of the rat. PMID- 4293650 TI - Activity of dephosphorylating enzymes in tissue cultures of mouse embryo cells in the course of infection with oncogenic polyoma virus. PMID- 4293651 TI - Activity of LDH isozymes in the tissue of children with neoplastic diseases. PMID- 4293653 TI - Template-active RNA isolated from an oncogenic virus. PMID- 4293652 TI - [Studies on the structure of aminopeptidase from particles of pig kidneys]. PMID- 4293654 TI - Plasma renin activity and renin-substrate concentration in patients with liver disease. PMID- 4293655 TI - Natriuretic effect of angiotensin in dogs revealed after administration of reserpine and guanethidine. PMID- 4293656 TI - Role of the autonomic nervous system in the renal vasoconstriction response to hemorrhage in the rabbit. PMID- 4293657 TI - Chemical assay of phospholipid renin preinhibitor in canine and human blood. PMID- 4293659 TI - Present knowledge of the rhinovirus group of viruses. PMID- 4293658 TI - A method for studying isolated resistance vessels from rabbit mesentery and brain and their responses to drugs. PMID- 4293660 TI - Metabolism of C21 steroids by incubated adrenals of ACTH treated rats. PMID- 4293661 TI - Pressor and oxitocic-like effects of angiotensin affected by aldosterone pretreatment in guinea-pigs. PMID- 4293662 TI - Presynaptic inhibition by gastrocnemius-soleus nerves. PMID- 4293663 TI - Renal and pressor actions of angiotensin in salt loaded and depleted rabbits. PMID- 4293664 TI - Accelerated and prolongated multiplication of antibody-forming spleen cells by Bordetella pertussis in mice immunized with sheep red blood cells. PMID- 4293665 TI - Avirulent Clostridium perfringens strains obtained by euflavine treatment. AB - Clostridium perfringens was incubated in the presence of euflavine (EU); the resistant mutants which were thus isolated had highly reduced capacity to release alpha-toxin. This fact was confirmed by lecithinase determinations and by immunoelectrophoresis. Injected into guinea pigs and into 6- to 7-day-old chicks, these mutants were completely avirulent. A study of their properties indicated biochemical differences between wild types and mutants. PMID- 4293666 TI - Antibiotic susceptibility patterns as aids in classification and characterization of gram-negative anaerobic bacilli. AB - Patterns of susceptibility of gram-negative anaerobic bacilli to antibiotics have been found to be distinctive and of significant help in classification and identification. Five major groups of gram-negative anaerobic bacilli have been defined on the basis of morphological and biochemical criteria. Antibiotic sensitivity patterns conform to these groupings and provide additional taxonomic criteria. The Bacteroides fragilis group is resistant to penicillin G, whereas the other groups are generally sensitive. B. fragilis strains are relatively sensitive to erythromycin, whereas the Sphaerophorus necrophorus group is resistant. B. melaninogenicus strains, B. oralis, and Fusobacterium are all more sensitive to kanamycin and neomycin than the other two groups. Kanamycin is more active against Fusobacterium strains than neomycin, but less active against all other groups. Colistin or polymyxin B is useful for distinguishing between the resistant B. fragilis and the sensitive S. necrophorus. Antibiotic susceptibility determinations may be more readily performed in clinical laboratories than certain biochemical tests recommended for differentiation of the gram-negative anaerobic bacilli and may serve as helpful adjuncts to morphological and biochemical observations in classifying and characterizing these organisms. The use of standardized procedures for antibiotic susceptibility tests is essential if comparable results are to be obtained in different laboratories. PMID- 4293667 TI - Plasma testosterone in idiopathic hirsutism, and the changes produced by adrenal and ovarian stimulation and suppression. PMID- 4293668 TI - The effect of norethandrolone (Nilevar) on growth in the female guinea-pig. PMID- 4293669 TI - Dynamic aspects of collagen biology. II. Degradation and metabolism. PMID- 4293670 TI - Metastatic renal embryoma: survival following therapy. PMID- 4293671 TI - Acute leukemia and infection. PMID- 4293672 TI - Bites by copperheads (Ancistrodon contortrix) in the United States. PMID- 4293673 TI - Fatal nonbacterial pneumonia associated with Adenovirus type 4. Occurrence in an adult. PMID- 4293674 TI - Renal pressor mechanisms. PMID- 4293675 TI - [Semiconductor properties and cytopathogenicity of quartz]. PMID- 4293676 TI - Lysosomal enzymes in relation to the toxicity of silica. PMID- 4293677 TI - Observations on the relationship between quartz cytotoxicity and fibrogenicity while testing the biological activity of synthetic polymers. PMID- 4293678 TI - Effect of berberine sulphate on Entamoeba histolytica. PMID- 4293679 TI - Agent of Marek's disease in tissue culture. PMID- 4293680 TI - Effect of suspending medium on heat resistance of spores of Clostridium perfringens. PMID- 4293681 TI - Inorganic pyrophosphate and ATP as energy donors in chromatophores from Rhodospirillum rubrum. PMID- 4293682 TI - Influence of host age on leukaemogenesis and virus proliferation after infection with a murine leukaemia virus. PMID- 4293683 TI - Cytopathic effects of the parainfluenza virus SV5 in Vero cells. PMID- 4293685 TI - Granular-cell myoblastoma of tongue. Report of a case. PMID- 4293684 TI - Transmission of excitation from the parasympathetic nerve to the smooth muscle. PMID- 4293686 TI - Diabetes mellitus and infantilism. PMID- 4293687 TI - A new type 3 attenuated poliovirus for possible use in oral poliovirus vaccine. PMID- 4293688 TI - The cat-scratch syndrome, many diseases or one disease? PMID- 4293689 TI - Comparative virology of the herpes group. PMID- 4293690 TI - In vitro investigations on murine leukemia viruses. PMID- 4293692 TI - [Prolonged prednisone treatment of hirsutism caused by virilizing adrenal hyperplasia without abnormalities on cortisol production]. PMID- 4293691 TI - Detergent-solubilized RNA polymerase from cells infected with foot-and-mouth disease virus. AB - The foot-and-mouth disease virus RNA polymerase complex was dissociated from cellular membranes with deoxycholate in the presence of dextran sulfate. The soluble polymerase complex was active in the cell-free synthesis of virus specific RNA; solubilization of the complex permitted direct analysis of the cell free reaction mixtures without recourse to RNA extraction. A major RNA-containing component found early during cell-free incubation ranged from approximately 140 to 300S. The final major products of the cell-free system were 37S virus RNA, 20S ribonuclease-resistant RNA, and a 50S component containing RNA. PMID- 4293693 TI - [Reduction of the incidence of recurrences of typho-paratyphoid fevers by intermittent chloramphenicol treatment. An analysis of 101 cases]. PMID- 4293694 TI - Steroid reactions on thin-layer films. PMID- 4293695 TI - Effect of total gastrectomy on the Zollinger-Ellison tumor: observations by second-look procedures. PMID- 4293696 TI - Treatment of clostridial infections with hyperbaric oxygen. PMID- 4293697 TI - The susceptibility of mycobacteria to rifamide and rifampicin. PMID- 4293698 TI - [Comparative somatic and radiographic studies in the 1st and 2d phases of puberty]. PMID- 4293699 TI - [Questions of the pathogenicity of REO viruses in suckling mice]. PMID- 4293700 TI - [Thermostability of toxoplasmin and its significance for the harmlessness of the skin test]. PMID- 4293701 TI - [Mechanism of hyperglycemia induced by ethacrynic acid]. PMID- 4293702 TI - Analysis of labeling patterns in soluble RNA preparations from green pea stem sections supplied with 14C-carboxyl-labeled indoleacetic acid. PMID- 4293703 TI - Studies on characteristics of poliovirus. I. Marker and temperature. PMID- 4293704 TI - The existence of two different metabolic patterns for the synthesis of RNA viruses. PMID- 4293705 TI - A new virus cultivated only in organ cultures of human ciliated epithelium. PMID- 4293706 TI - Further properties of equine arteritis virus. PMID- 4293707 TI - Copper sulfate-induced hemolytic anemia. Inhibition of glucose-6-phosphate dehydrogenase and other possible etiologic mechanisms. PMID- 4293708 TI - [Strains of parainfluenza virus type 4, isolated in a day nursery]. PMID- 4293709 TI - Cytopathic effect and growth of SV 40 in rhesus monkey kidney cell cultures. PMID- 4293710 TI - The inhibition of NADH oxidation in mammalian mitochondria by chloramphenicol. PMID- 4293711 TI - Polyriboadenylate synthesis by nuclei from developing sea urchin embryos. I. Characterization of the ATP polymerase reaction. PMID- 4293713 TI - Central respiratory failure reversed by treatment. PMID- 4293714 TI - [On the pathology and clinical studies of bronchial adenoma]. PMID- 4293715 TI - [Development of the thymus and adrenal glands during the growth of a tumor graft in rats. Preliminary note]. PMID- 4293716 TI - Current approaches to the mechanism of energy-coupling in the respiratory chain. Studies with yeast mitochondria. PMID- 4293717 TI - Surgical management of tumors of intraoral minor salivary glands. Report of eighty cases. PMID- 4293718 TI - Classification of primary malignant tumors of liver in infancy and childhood. PMID- 4293719 TI - [Viral appendicitis]. PMID- 4293720 TI - [Adrenal and extra-adrenal effects of a synthetic polypeptide (Ba 30920) stimulating the adrenal cortex]. PMID- 4293722 TI - Reactive amino groups in baker's yeast cytochrome C. PMID- 4293721 TI - Studies on P-450. II. On the absorption spectrum of P-450 in mitochondrial fragments from bovine adrenal cortex. PMID- 4293723 TI - Study of a virus-containing hematopoietic cell line and a melanoma cell line derived from a patient with a leukemoid reaction. PMID- 4293724 TI - The effects of sodium and angiotensin upon renal renin and renal, adrenal, and salivary gland glucose-6-phosphate dehydrogenase. Evidence for a proximal tubular effect of angiotensin. PMID- 4293725 TI - [Contribution to the study of oligosyndactyly]. PMID- 4293726 TI - Phenomenon of tumour transfer by skin grafting. PMID- 4293727 TI - Recognition of the individuality of tumour strain by sensitized peritoneal lymphoid cells. PMID- 4293728 TI - Increased tumour induction by adenovirus type 12 in thymectomized mice and mice treated with anti-lymphocyte serum. PMID- 4293729 TI - Immunological reactivity to peptides related to angiotensin. PMID- 4293730 TI - Relationship between the subunits and "T" antigens of adenovirus type 12. PMID- 4293731 TI - Heat-labile mcaroglobulin revealed in adenovirus 12 tumour sera by gel electrophoresis. PMID- 4293732 TI - Multinucleated muscle fibres: induction of DNA synthesis and mitosis by polyoma virus infection. PMID- 4293733 TI - Parathyroid function and the renal excretion of 3'5'-adenylic acid. PMID- 4293734 TI - [The hypothalamic postgravidity syndrome]. PMID- 4293736 TI - [Study of the metabolism of calcium and of osseous physiopathology with radioisotopes]. PMID- 4293735 TI - [Intra-adrenal disorders of steroidogenesis in certain clinical conditions]. PMID- 4293737 TI - [Addison's disease cured by antitubercular antibiotic therapy. Hormonal study and discussion]. PMID- 4293738 TI - The nature of adrenocorticosteroid activity. PMID- 4293739 TI - [Comparative studies of soluble organic proteins from tumor- and normal tissues using free electrophoresis]. PMID- 4293740 TI - [Quantitative study of the Yoshida AH 130 ascites hepatoma]. PMID- 4293741 TI - Further studies on cytomegalovirus mononucleosis in previously healthy individuals. PMID- 4293743 TI - The epizootiology of the vesicular stomatitis viruses: a reappraisal. PMID- 4293742 TI - Fixation of the annulus of the mitral valve with a rigid ring. Hemodynamic studies. PMID- 4293745 TI - The sensitivity of the complement fixation test for the detection of adenovirus infections in infants and children with lower respiratory disease. PMID- 4293744 TI - Immunization with live type 4 adenovirus: determination of infectious virus dose and protective effect of enteric infection. PMID- 4293746 TI - Epidemiology of infections with rhinovirus types 43 and 55 in a group of university of Wisconsin student families. PMID- 4293747 TI - Erythrocytosis and hyperlipemia as manifestations of hepatic carcinoma. PMID- 4293748 TI - Contrast nasopharyngography of angiofibromata. PMID- 4293750 TI - Experimental infection with Streptomyces madurae as a function of collagenase. PMID- 4293749 TI - [Autoradiographic analysis of cell proliferation in normal human oral mucosa and tumor tissue in vitro]. PMID- 4293751 TI - A neurological disorder preceding Hodgkin's sarcoma. PMID- 4293752 TI - Lysis of clots in serum by proteolytic enzymes other than trypsin and plasmin. PMID- 4293753 TI - Therapy of infective gastroenteritis. PMID- 4293754 TI - Electron spin resonance studies on proton-irradiated ribonuclease and lysozyme. PMID- 4293755 TI - Inactivation and trapped radicals in dry trypsin exposed to ultraviolet light. PMID- 4293756 TI - Ultraviolet-induced excited states in deoxyribonucleic acid. PMID- 4293757 TI - Free radicals induced in enzymes by electrons and heavy ions. PMID- 4293758 TI - [Morphology of oncogenic viruses. II. Deoxyribonucleic acid viruses]. PMID- 4293759 TI - [A clinical method of measuring vascular sensitivity to angiotensin. Comparison with vascular sensitivity to noradrenaline]. PMID- 4293760 TI - Cis-trans isomerism in naphthoquinones: interconversion and participation in oxidative phosphorylation. AB - Synthetic phylloquinone was resolved into cis and trans isomers by thin-layer chromatography. The two isomers had identical ultraviolet spectra characteristic of vitamin K(1) and were differentiated by nuclear-magnetic-resonance spectroscopy on the basis of the displacement of the peak corresponding to the olefinic methyl group in the naphthoquinone side chain. Studies on the restoration of electron transport coupled to phosphorylation in irradiated preparations of Mycobacterium phlei showed that only the trans isomer was active with substrates linked to nicotinamide-adenine dinucleotide. The purified trans phylloquinone was enzymatically converted to the cis isomer. Under similar conditions, cis vitamin K(1) gave rise to the trans-naphthoquinone. The natural naphthoquinone of M. phlei vitamin MK(9)(II-H) was similarly resolved into cis and trans isomers. PMID- 4293761 TI - Control of aldosterone secretion by the pituitary gland. AB - In the rat, the pituitary gland is essential for the stimulation of aldosterone secretion by sodium depletion. Hypophysectomy abolishes the response to sodium depletion, whereas whole pituitary gland injections partially restore it. The response cannot be restored by injections of either adrenocorticotropin or growth hormone, nor by adrenocorticotropin plus thyroxin. The pituitary gland must secrete a hormone or possibly several hormones which are necessary for the adrenal gland to respond to sodium depletion. PMID- 4293762 TI - Extrahepatic biliary decompression in traumatized canine livers. PMID- 4293763 TI - Alcohol as an impurity in LADH preparations. Determination and removal. PMID- 4293764 TI - Intestinal absorption and esterification of vitamin D3-1,2-3H in man. PMID- 4293765 TI - Patient presentations: panel discussion. Arrhenoblastoma in a 13-year-old girl. PMID- 4293766 TI - Ovarian tumors in infancy, childhood, and adolescence. PMID- 4293767 TI - [Influence of some pharmacodynamic substances on the ionic composition of the smooth muscle fiber of the rat aorta]. PMID- 4293768 TI - Evidence for confromational differences between oxidized and reduced cytochrome oxidase. PMID- 4293769 TI - Hydrolysis of the polymer formed from NAD with rat liver phosphodiesterase yielding nucleoside 5'monophosphate. PMID- 4293770 TI - [Research on the Shiff periodic-acid positivity of erythroblasts of umbilical cord blood]. PMID- 4293771 TI - [Compared study of electronic paramagnetic resonance spectra of amino acids and polyamino acids, exposed to the action of ionizing radiation in the solid phase]. PMID- 4293772 TI - [Study of antibody inhibitors of hemagglutination in hamsters bearing primary tumors and grafts induced by adenovirus 12]. PMID- 4293773 TI - [Oncolytic power in vivo of the Newcastle virus with regard to sarcoma ascitic Yoshida]. PMID- 4293774 TI - [Effect of potassium perchlorate on iodine metabolism in the thyroidal tissue in vitro]. PMID- 4293775 TI - A study of the action of angiotensin on the superior cervical ganglion in comparison with other ganglion stimulating agents. PMID- 4293776 TI - Topical and remote effects of drugs upon tissue clearance. PMID- 4293777 TI - On the question of the mechanism of inhibitory effect of acidosis on anaerobic glycolysis of erythrocytes. PMID- 4293778 TI - [The decontamination of water containing adenoviruses]. PMID- 4293779 TI - The role of deoxyribonucleic acid in ribonucleic acid synthesis. 13. Modified purification procedure and additional properties of ribonucleic acid polymerase from Escherichia coli W. PMID- 4293780 TI - Yeast aldehyde dehydrogenase. I. Purification and crystallization. PMID- 4293781 TI - The enzymatic significance of S-acetylation and N-acetylation of 3 phosphoglyceraldehyde dehydrogenase. PMID- 4293782 TI - The properties and enzymatic significance of the enzyme-diphosphopyridine nucleotide compound of 3-phosphoglyceraldehyde dehydrogenase. PMID- 4293783 TI - Glycolytic control mechanisms. V. Kinetics of high energy phosphate intermediate changes during electrical discharge and recovery in the main organ of Electrophorus electricus. PMID- 4293784 TI - Quantitative thin layer chromatography of lipids. PMID- 4293785 TI - The effect of silicic acid and alkali concentration on the saponification of lipids. PMID- 4293786 TI - [Fingerprints developing on silica gel thin layer plates]. PMID- 4293787 TI - Neurohypophysial peptide interaction with magnesium in avian vascular smooth muscle. AB - 1. The contractile responses of helically cut vascular strips of chickens to vasoactive agents were studied.2. Large pulmonary arteries were contracted by neurohypophysial peptides, but not by angiotensin, acetylcholine, histamine, 5 hydroxytryptamine, bradykinin or eledoisin. The activity of oxytocin was greater than that of arginine vasopressin.3. Vasodilator effects of oxytocin upon small (200-500 mu diameter) mesenteric and muscular arteries were demonstrable, but inconsistent.4. Magnesium potentiated in a parallel fashion the vasoconstrictor effects of oxytocin and of arginine vasopressin.5. Deamino-oxytocin was potentiated by magnesium. This finding suggests a difference between the peptide protein interactions of tissue receptors and those of neurophysin. PMID- 4293788 TI - A study of cholinoceptive cells in the lateral geniculate nucleus. AB - 1. The dorsal lateral geniculate nucleus (LGN) of the cat stains densely for acetylcholinesterase, which is present in intra-axonal and extracellular locations.2. Acetylcholine (ACh), cholinomimetic drugs, anticholinesterases and ACh antagonists were administered iontophoretically to neurones in the LGN.3. ACh excited eighty-six of 184 (46.7%) geniculate neurones and depressed seven (3.8%).4. The excitatory response to ACh was frequently larger than that to L glutamate and had a comparable time course.5. There was a considerable variation in the proportion of ACh sensitive cells in different animals. ACh firing was facilitated by optic nerve or visual stimulation.6. Carbamylcholine was the most active of the choline esters tested, frequently exceeding ACh in potency. The other choline esters and nicotine were consistently less active than ACh.7. Anticholinesterases, eserine, neostigmine and edrophonium potentiated the action of ACh, and often caused excitation. Eserine caused an initial small enhancement in the amplitude of the focal potential evoked by optic nerve stimulation followed by a reduction in amplitude and prolongation of duration of the potential.8. Atropine and benzoquinonium effectively prevented the ACh excitation of many cells. Dihydro-beta-erythroidine failed to cause a significant reduction in the magnitude of the ACh response. All three ACh antagonists failed to reduce the excitant effects of optic nerve or visual stimulation.9. Stimulation of the mesencephalic reticular formation caused either an enhancement or a reduction in the excitability of ACh sensitive neurones in the LGN. Benzoquinonium abolished the excitatory effects of reticular formation stimulation.10. The findings presented in this paper suggest that ACh is the transmitter released by terminals of nerves of the reticular formation projection to the LGN. PMID- 4293791 TI - Overt herpes-T infection in squirrel monkeys (Saimiri sciureus). PMID- 4293790 TI - The relative sensitivity to vibration of muscle receptors of the cat. AB - 1. Longitudinal vibration was applied to the de-efferented soleus muscle of anaesthetized cats while recording the discharge of single afferent fibres from the proprioceptors within the muscle. Conditions were defined under which vibration can be used to excite selectively the primary endings of muscle spindles without exciting the secondary endings of muscle spindles or Golgi tendon organs.2. Frequencies of vibration of 100-500 c/s were used. The maximum amplitude of vibration which the vibrator could produce fell with increasing frequency; it was 250 mu (peak to peak) for 100 c/s and 20 mu for 500 c/s.3. Primary endings of muscle spindles were very sensitive to vibration. Most could be ;driven' to discharge one impulse for each cycle of vibration over the whole of the above range of frequencies, provided the initial tension was moderate (20 200 g wt.). The amplitude of vibration required to produce driving usually varied by less than a factor of two over the whole range of frequencies. The most sensitive endings could be driven by vibrations of below 10 mu amplitude.4. Stimulation of single fusimotor fibres, whether static or dynamic fusimotor fibres, increased the sensitivity of primary endings to vibration. Contraction of the main muscle, produced by stimulating alpha motor fibres, reduced the sensitivity of primary endings even when fusimotor fibres were also being stimulated.5. The secondary endings were very insensitive to longitudinal vibration and with the amplitudes available not one of twenty-five endings could be driven at 150 c/s or above; one ending could be driven at 100 c/s by vibration of 250 mu amplitude. Stimulation of single fusimotor fibres, probably all of which were static fusimotor fibres, made them slightly more sensitive to vibration but none of them approached the sensitivity of the primary endings.6. The Golgi tendon organs were as insensitive as the secondary endings when the muscle was not contracting and none could be driven at any frequency in spite of quite high tensions in the muscle. However, when the muscle was made to contract by stimulating alpha fibres in ventral root filaments the tendon organs became appreciably more sensitive, the degree of sensitization increasing approximately with the strength of the contraction. They never became as sensitive as the primary endings, and with the amplitudes of vibration available none was driven at frequencies of over 250 c/s.7. When the amplitude of vibration was somewhat below that required to produce driving of an ending it still produced some increase in its mean frequency of discharge. However, amplitudes of vibration of 25-50 mu applied to a non-contracting muscle, whether with or without fusimotor stimulation, produced driving of nearly all primary endings without any significant increase in the mean frequency of firing of secondary endings or Golgi tendon organs. Such vibration can therefore be used as a specific stimulus for the primary endings in order to investigate the central effects or repetitive discharge of the Ia afferent fibres from them.8. Experiments on endings in the peroneus longus muscle showed that these behaved similarly to those in soleus. PMID- 4293789 TI - The responses of thalamic neurons to iontophoretically applied monoamines. AB - 1. The effects of noradrenaline (NA), adrenaline, dopamine (DA) 5 hydroxytryptamine (5-HT) and a number of related drugs were tested on the extracellularly recorded responses of neurones in the feline thalamus. Substances were applied iontophoretically and tested on synaptically, antidromically and chemically evoked neuronal activity.2. NA, adrenaline, isoprenaline and 5-HT had a variety of effects, depressing some cells, exciting others and not affecting the responses of a third group. DA depressed most of the cells tested; excitation was not observed with this compound.3. The magnitude of depressant actions and their duration varied considerably. The more sensitive cells responded to extremely small amounts of catecholamine or 5-HT and recovery often took several minutes. Recovery after DA was always rapid. Neurones in the dorsal thalamus were generally more susceptible to depression than those in the ventro-basal complex.4. Excitatory responses were most marked in the ventro-basal complex of the thalamus. Desensitization occurred if NA or adrenaline was applied repeatedly and this tachyphylaxis lasted for several minutes. After desensitization to the excitatory effects, some of these cells were depressed by catecholamines. These findings suggest the presence of at least two types of membrane receptor.5. beta adrenergic antagonists (alderlin, D-INPEA and MJ 1999) and alpha-antagonists (phentolamine, dibenzyline and chlorpromazine) had pronounced depressant actions on some thalamic neurones. With the exceptions of D-INPEA and MJ 1999 they also excited cells that were excited by the catecholamines. Alderlin and phentolamine had both excitatory and inhibitory effects on some cells.6. The monoamine oxidase inhibitor, iproniazid, depressed neurones which were sensitive to NA depression. It did not appear to potentiate the effects of NA on most of the cells tested.7. Reticular formation stimulation depressed some neurones in the thalamus and excited others. The depressant effects of NA and reticular formation stimulation were reduced or abolished by an intravenous injection of picrotoxin (1 mg/kg).8. It is suggested that NA and 5-HT may be inhibitory transmitters in the thalamus, released at the terminals of ascending pathways from the brain stem that have been defined by fluorescence microscopy. The excitatory actions of these compounds may also be related to a synaptic role. PMID- 4293792 TI - [Cytomegaly, vaccination and sudden infant death]. PMID- 4293793 TI - Concentrations of pyruvate kinase and lactate dehydrogenase in the kidney of the alloxan diabetic rat. PMID- 4293794 TI - Hidradenoma of the vulva in pregnancy with recurrence after local excision. PMID- 4293795 TI - Biochemical investigations of the actions of corticotrophins on the adrenal cortex. PMID- 4293796 TI - Several aspects of the influence of vasopressin on pituitary-adrenal activity. PMID- 4293797 TI - Corticotrophin stimulation tests. PMID- 4293798 TI - Some aspects of the pharmacology of metyrapone. PMID- 4293799 TI - The assessment of hypothalamic-pituitary-adrenocortical function in man. PMID- 4293801 TI - [Endocrinologic diagnosis in hypophyseal adenoma]. PMID- 4293800 TI - Evaluation of pituitary-adrenal function in man. PMID- 4293802 TI - [Effects of modifications of central temperature on experimental poliomyelitis in mice]. PMID- 4293803 TI - [Non-lithiasic cholecystopathies]. PMID- 4293804 TI - [Medical treatment of non-lithiasic cholecystopathies]. PMID- 4293805 TI - [Non lithiasic and non-cancerous disorders of the gallbladder and cystic duct: surgical treatment]. PMID- 4293806 TI - [Malformations of the female genital tract and those of the upper urinary tract which may be associated with them: morphological and physiopathological study]. PMID- 4293807 TI - [Semiology and diagnosis of associated malformations of the female genital tract and the upper urinary tract]. PMID- 4293808 TI - [The anatomoclinical syndrome of bilateral renal agenesis]. PMID- 4293809 TI - [Biochemical anomalies in rheumatoid polyarthritis]. PMID- 4293810 TI - [Gout aggravated by therapy]. PMID- 4293811 TI - [Heteroantigens of tumor cells and the problem of cell differentiation]. PMID- 4293812 TI - [Experimental infections of cattle with human adenovirus (type 1)]. PMID- 4293813 TI - Cushing's syndrome associated with a "corticotrophin"-producing bronchial neoplasm neoplasm (results of corticotrophin assays and of pituitary-adrenal function tests). PMID- 4293814 TI - Effect of reserpine on prostate gland fructose. PMID- 4293815 TI - [Contribution to the question of gliosic tumors of the posterior lobe of hypophysis]. PMID- 4293816 TI - The Landry-Guillain-Barre syndrome. A survey and a clinical report of 127 cases. PMID- 4293817 TI - Isoniazid-induced vitamin B6 deficiency. Metabolic studies and preliminary vitamin B6 excretion studies. PMID- 4293818 TI - Alveolar cells: protein biosynthesis. PMID- 4293819 TI - Carcinoma of the trachea. PMID- 4293820 TI - Peripheral neuropathy in long-term diphenylhydantoin therapy. PMID- 4293821 TI - Acrylamide poisoning. PMID- 4293822 TI - Production of lung carcinomas in C57BL mice exposed to a cigarette smoke and air mixture. PMID- 4293823 TI - Improving the psychiatric services. PMID- 4293824 TI - Adrenocortical function in children with severe protein-calorie malnutrition. PMID- 4293825 TI - Stimulation and inhibition of adrenal RNA synthesis by ACTH. PMID- 4293826 TI - Neural net analogs of rhythmic activity in the nervous system. PMID- 4293827 TI - Observations on the ultrastructure of a netastasizing beta cell islet tumor. PMID- 4293828 TI - Interactions of adenosine tetraphosphate with myosin and actomyosin. PMID- 4293829 TI - The binding of calcium at lipid-water interfaces. PMID- 4293830 TI - Effect of glucocorticoids on nucleic acid metabolism of rat ascites hepatoma. PMID- 4293831 TI - Chromosomal features in ascites and metastatic lesions of cancer clones. PMID- 4293832 TI - Encephalomyocarditis virus infections in Florida, 1960-1966. PMID- 4293833 TI - Mucinous adenocarcinoma of the bovine ovary. PMID- 4293834 TI - Clinico-pathologic conference from the School of Veterinary Medicine, University of Pennsylvania. PMID- 4293835 TI - The treatment of glioblastoma multiforme of the brain. PMID- 4293836 TI - Radioisotope (gamma) cerebral angiography. Technical note. PMID- 4293837 TI - Growth in mentally retarded children. PMID- 4293838 TI - New electromechanical method for the assay of heparin in vitro. PMID- 4293839 TI - Lymphangiography by lymph-node injection. PMID- 4293840 TI - The mechanism of staphylococcal alpha toxin action on smooth muscle. PMID- 4293841 TI - [Is a lymphangiography with fat-soluble contrast media (lipiodol ultrafluid) contraindicated? (Findings in animal experiments on para-aortic and inguinal lymph nodes on 10 dogs for clarification of eventual formation of granuloma)]. PMID- 4293842 TI - [Research on enterovirus infections in the Federal District]. PMID- 4293843 TI - In vitro incorporation of amino-acids into the contractile protein of human blood platelets. PMID- 4293844 TI - New vasoconstrictor, bovine peptide B, released during blood coagulation. PMID- 4293845 TI - Induction of tumours in hamsters with infectious canine hepatitis virus. PMID- 4293846 TI - Mutation towards dextran sulphate resistance in type 1 poliovirus. PMID- 4293847 TI - Radioimmunoassay of angiotensin in human plasma. PMID- 4293849 TI - Pituitary-adrenal regulation of ceruloplasmin. PMID- 4293848 TI - Electron spin resonance in biological tissues. PMID- 4293850 TI - Inhibition of spinal neurons by glycine. PMID- 4293851 TI - Acetylcholine, strychnine and spinal inhibition. PMID- 4293852 TI - Pharmacological characteristics and ionic bases of a 2 component postsynaptic inhibition. PMID- 4293853 TI - Increase in permeability of the postsynaptic membrane to potassium produced by 'nembutal'. PMID- 4293854 TI - New observations regarding the auriculotemporal syndrome. PMID- 4293855 TI - Bronchial neoplasm with endocrine, metabolic, and neurological manifestations. Report of a case. PMID- 4293856 TI - Human infection with the virus of vesicular stomatitis during an epizootic. PMID- 4293857 TI - Arborizing pulmonary embolization following lymphangiography. Report of three cases and an experimental study. PMID- 4293858 TI - A critical evaluation of selective celiac and superior mesenteric angiography in the diagnosis of pancreatic diseases, particularly malignant tumor: facts and "artefacts". PMID- 4293859 TI - Total-body opacification in the diagnosis of Wilms's tumor and neuroblastoma. A note of caution. PMID- 4293860 TI - Viruses and chronic bronchitis. PMID- 4293861 TI - Effect of angiotensin on renal function of the dog. PMID- 4293862 TI - Effect of triamterene on folic reductase activity and reproduction in the rat. PMID- 4293863 TI - Recent developments in the understanding and teaching of educationally subnormal children in England and Wales. PMID- 4293864 TI - [Multiple glomus tumors and blue rubber bleb nevus]. PMID- 4293865 TI - [Ultrastructural modifications induced by canine hepatitis virus in dog kidney cells]. PMID- 4293866 TI - [Evolution of cytomegalic virus disease in thymectomized isogenic radiation chimeras]. PMID- 4293867 TI - [Flexion spasms in infants. Study of the urinary excretion of 17 hydroxycorticosteroids and titers of cortisol secretion during their treatment with A.C.T.H]. PMID- 4293868 TI - [Pseudomonas aeruginosa infections in a premature infant center in the years 1960 to 1963]. PMID- 4293869 TI - [Phospholipids in quartz-damaged macrophages]. PMID- 4293870 TI - [The pathogenesis of diabetes mellitus]. PMID- 4293872 TI - [Serum levels of certain enzymes in hepatic cirrhosis]. PMID- 4293871 TI - [Comparison between serum and ascitic enzyme levels in hepatic cirrhosis]. PMID- 4293873 TI - Adrenocortical cytogenesis in the adult male golden hamster. A radioautographic study using tritiated-thymidine. PMID- 4293874 TI - A molybdate-activated phosphatase in arterio-venous anastomoses and in nerve ganglia satellite cells. PMID- 4293875 TI - [Pitfalls in the diagnosis of cervical glomus tumors. (Apropos of 3 cases)]. PMID- 4293876 TI - [Intramolecular correlation of coenzymes. 3. Nicotinamide-pentamethylene adenosine-pyrophosphate]. PMID- 4293877 TI - [Hepatoma 23 years after pericardectomy]. PMID- 4293878 TI - Effects of dipyridamole on heart muscle mitochondria. PMID- 4293879 TI - [Early symptoms in 75 cases of brain tumors in childhood]. PMID- 4293880 TI - [The changed picture of purulent meningitis under the influence of current therapy]. PMID- 4293881 TI - [Contribution on functional adrenal cortex diagnosis with ACTH in infancy and childhood]. PMID- 4293882 TI - [Changes in cortisol metabolism following depot ACTH administration in healthy children and those with salaam convulsion]. PMID- 4293883 TI - [The metopirone test in children]. PMID- 4293884 TI - [Bronchoscopic diagnosis of a benign tumor (cylindroma) obstructing the orifice of the left main trunk. Treatment by bronchotomy-curettage, completed by left inferior lobectomy]. PMID- 4293885 TI - [The cancer problem in fundamental research]. PMID- 4293886 TI - [On the presence of Cl. perfringens in meat foods sold in Modena]. PMID- 4293887 TI - [On the interrelationships between nervous and humoral (hormonal) factors of regulation in higher animals]. PMID- 4293888 TI - [Determining the standard and variant foot-and-mouth disease virus--the basis of specific prevention]. PMID- 4293889 TI - [The effect of enriching Frenkel's medium on the reproduction of the foot-and mouth disease virus]. PMID- 4293890 TI - [Biochemical indices in the culturing of foot-and-mouth disease virus]. PMID- 4293892 TI - [Antigenic properties of foot-and-mouth disease virus strain Ai]. PMID- 4293891 TI - [Multiplication of foot-and-mouth disease virus in swine embryo kidney tissue culture]. PMID- 4293893 TI - [Rheumatism and pregnancy]. PMID- 4293894 TI - [The daily rhythm of Na-K in the saliva and its modification under the action of ACTH, prednisolone, DOCA and smoking in patients with hypertension]. PMID- 4293895 TI - [Studies on the structure of ribosomal RNA from normal and tumor tissues. V. Change in the optical rotation after thermal denaturation]. PMID- 4293896 TI - [Enzymatic induction in the development of the crystalline lens]. PMID- 4293897 TI - The thiamine pyrophosphatase technique as a indicator of morphology of the Golgi apparatus in the neurons. VI. Studies on the spinal cord, hippocampus, and trigeminal ganglion. PMID- 4293898 TI - [Electron microscopy studies on foreign body accumulation in the nucleus and cytoplasm of ascites tumor cells]. PMID- 4293899 TI - [Hemagglutination inhibiting (HAI) antibodies against the virus of parainfluenza 3 (PI 3) in serum of horses and cattle with periodic opthalmics]. PMID- 4293900 TI - [Unusual symptomology and course of a mediastinal chemodectoma]. PMID- 4293901 TI - Major surgery in the presence of a primary capillary haemorrhagic disorder. PMID- 4293902 TI - [The timely recognition of spinal tumors]. PMID- 4293903 TI - [Indication and complications of examination of the spinal canal with contrast media]. PMID- 4293904 TI - [Sacral and leg pains]. PMID- 4293906 TI - [Effect of thymectomy on polyoma induction]. PMID- 4293905 TI - [Cervical myelopathy]. PMID- 4293907 TI - [Primary cancer of the liver in children]. PMID- 4293908 TI - [The differential diagnosis of corticosteroma and Itsenko-Cushing's disease]. PMID- 4293910 TI - [Angiotensinase activity in a modified skin test using angiotensin]. PMID- 4293909 TI - [On the morphologic and histochemical behavior of the blood vessel wall in arterial obstruction]. PMID- 4293911 TI - [Case of giant retroperitoneal tumor with hypoglycemia]. PMID- 4293912 TI - [Clinically observed side effects of more recent antibiotics. Amphotericin-B bacitracin-cycloserine-neomycin-novobiocin-polymyxin]. PMID- 4293913 TI - [On the problem of experimental rheumatism and the status of the sympatho-adrenal system during the disease]. PMID- 4293914 TI - [Diagnostic difficulties in cystosarcoma phyllodes]. PMID- 4293915 TI - [Studies on the hypophysis adrenal cortex function in children. 1. ACTH response test with serum free 17-OHCS as an indicator]. PMID- 4293916 TI - Testing compliance with threshold limit values for respirable dusts. PMID- 4293917 TI - Radioisotope liver scans in pediatrics. PMID- 4293918 TI - Experimental renal glomerulography. PMID- 4293919 TI - Hemorrhage in normal man: effect on renin, cortisol, aldosterone, and urine composition. PMID- 4293920 TI - Quantitative studies of the bacterial flora of open skin wounds: the effect of topical antibiotics. PMID- 4293921 TI - Syndactylism. PMID- 4293922 TI - Maintenance in the community: a study of psychiatric after-care and rehospitalization. PMID- 4293924 TI - Inhibition of renin release by vasopressin and angiotensin. PMID- 4293923 TI - Prognosis and treatment of idiopathic facial (Bell's) palsy. PMID- 4293925 TI - The nature of the biochemical lesion in avian renal riboflavinuria. I. Effect of genotype on renal riboflavin metabolism. PMID- 4293927 TI - Radical transfer reactions and chemical protection in the dry state. Electron spin resonance studies on irradiated mixtures of ribonuclease and glycyl-glycine. PMID- 4293926 TI - The response of the respiratory chain and adenine nucleotide system to oxidative phosphorylation in yeast mitochondria. PMID- 4293928 TI - An evaluation of the Mitchell hypothesis of chemiosmotic coupling in oxidative and photosynthetic phosphorylation. PMID- 4293929 TI - Studies of phosphorus metabolism by isolated nuclei. IX. Nucleolar nucleosidediphosphatase activity. PMID- 4293930 TI - Acid phosphatase analysis in sea urchin eggs and blastulae. PMID- 4293931 TI - [Notes on the hypophysial ACTH reserve in Turner's syndrome]. PMID- 4293932 TI - Nearest neighbour base sequence analysis of the deoxyribonucleic acids of a further three mammalian viruses: Simian virus 40, human papilloma virus and adenovirus type 2. PMID- 4293933 TI - Transformation of bovine cell cultures by preparations of polyoma virus. PMID- 4293934 TI - Electrophoretic evidence for a single protein component in the capsid of polyoma virus. PMID- 4293935 TI - Comparative growth and selection of small plaque and large plaque encephalomyocarditis virus in the absence of inhibitors from agar. PMID- 4293936 TI - The mutability of small-plaque-forming encephalomyocarditis virus. PMID- 4293937 TI - The effects of substituted benzimidazoles on the growth of viruses and the nucleic acid metabolism of host cells. PMID- 4293939 TI - The morphology of three previously uncharacterized human respiratory viruses that grow in organ culture. PMID- 4293938 TI - DNA polymerase induced by Simian virus 40. PMID- 4293940 TI - Nature of the inactivating action of trypsin on foot-and-mouth disease virus. PMID- 4293941 TI - Effect of actinomycin D on the synthesis of viral antigen in cercopithecus kidney cells infected with SV 40. PMID- 4293942 TI - [Microanalysis of trichloroethy phosphate in biological materials]. PMID- 4293943 TI - Experiences in laboratory diagnosis of herpes simplex, varicella-zoster, and vaccinia virus infections in routine medical practice. PMID- 4293944 TI - A comparison of the lipolytic effects of beta-1-24-corticotropin and extracted porcine ACTH. PMID- 4293945 TI - Renin-like enzyme in the adrenal gland. AB - The rabbit adrenal gland contains an enzyme which reacts with renin substrate to form a vasopressor polypeptide, probably angiotensin I. In view of the strong effects of angiotensin on secretion of aldosterone and catecholamine, this finding suggests that there may be an intra-adrenal mechanism for the control of adrenal secretions. PMID- 4293946 TI - [Arterial hypertension caused by pheochromocytoma. Apropos of 20 cases]. PMID- 4293947 TI - [The bones in myopathies]. PMID- 4293948 TI - [Male Turner's syndrome]. PMID- 4293949 TI - [Was the 1st case of hyperparathyroidism a diagnostic error?]. PMID- 4293950 TI - [A further case of the Schwartz-Bartter syndrome. The mode of action of antidiuretic hormone]. PMID- 4293951 TI - [Calcitonin and thyrocalcitonin]. PMID- 4293952 TI - [On a case of leukemia with large lymphocytes and terminal reticulosarcoma]. PMID- 4293953 TI - [Humoral influence of regeneration of the cirrhotic liver]. PMID- 4293954 TI - Effects of intra-arterial mepivacaine and bupivacaine on neuromuscular transmission in man. PMID- 4293955 TI - Renal failure in patients with cirrhosis of the liver. 3. Evaluation of intrarenal blood flow by para-aminohippurate extraction and response to angiotensin. PMID- 4293956 TI - Quadrivalvular rheumatoid heart disease associated with left bundle branch block. PMID- 4293957 TI - [21-hydroxylase deficiency detected late in a man with chronic asthenia]. PMID- 4293958 TI - [Hypoglycemia controlled by diazoxide in a case of malignant cholangioma]. PMID- 4293959 TI - The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas. AB - 1. The labelling of guinea-pig pancreas phospholipids in vivo after intraperitoneal injection of [(32)P]orthophosphate is described. 2. Acyl-CoA synthetase activity in pancreas homogenates has been studied. There is no absolute requirement for added fatty acids, indicating an adequate supply of endogenous fatty acids in these preparations. 3. Phosphatidic acid is formed in guinea-pig pancreas preparations by two distinct routes, namely the acylation of l-3-glycerophosphate and the phosphorylation of 1,2-diglyceride. Phosphatidic acid formed by either mechanism is converted into phosphatidylinositol by guinea pig pancreas in vitro. 4. The enzymes of pancreas that convert phosphatidic acid into phosphatidylinositol via CDP-diglyceride have been characterized. 5. Addition of bovine serum albumin is necessary in assaying certain of these enzymes. PMID- 4293960 TI - Influence of temperature acclimatization on the temperature-dependence and ouabain-sensitizing of goldfish intestinal adenosine triphosphatase. AB - 1. Homogenates of goldfish intestinal mucosa were separated into various fractions by differential centrifugation. Both adenosine-triphosphatase and beta glycerophosphatase activities were found to be concentrated mainly in a membrane fraction which sedimented after 1200000g-min. 2. This membrane adenosine triphosphatase system was activated by Na(+)+K(+) and inhibited by ouabain. 3. The ouabain-sensitive adenosine-triphosphatase activity was high and the ouabain insensitive activity low in membrane fractions prepared from fish acclimatized previously to 8 degrees . The opposite was true for fish acclimatized to 30 degrees . 4. The Arrhenius plots of ouabain-sensitive and ouabain-insensitive adenosine-triphosphatase activities, measured from 5 degrees to 30 degrees , showed discontinuities at incubation temperatures that varied with the previous acclimatization temperature of the fish. 5. It is considered that modification of the membrane adenosine-triphosphatase system in goldfish intestinal mucosa may serve to regulate Na(+) transport at different environmental temperatures. PMID- 4293961 TI - Measurements of tryptophan pyrrolase in vivo: induction and feedback inhibition. PMID- 4293962 TI - The binding of adenine nucleotides to the mannitol-I-phosphate dehydrogenase of Escherichia coli. PMID- 4293963 TI - Starch-gel investigations of the relationships between dehydrogenase proteins. PMID- 4293964 TI - Chemical modification of aminoacyl ligases and the effect on formation of aminoacyl-tRNA. PMID- 4293965 TI - Some aspects of the apparent glucose-6-phosphatase activity in the pancreatic islets of mammals. PMID- 4293966 TI - Derepression of phosphomonoesterase and phosphodiesterase activities in Aerobacter aerogenes. PMID- 4293967 TI - Electrophoretic variants of xanthine dehydrogenase in Drosophila melanogaster. II. Enzyme kinetics. PMID- 4293968 TI - The enzymatic reduction of ferrihemoglobin. I. The reduction of ferrihemoglobin in red blood cells and hemolysates. PMID- 4293970 TI - [On inactivation of MHV-3 hepatitis virus by intestinal tissue of mice treated with prednisolone]. PMID- 4293969 TI - The role of the adrenal medulla in the hypoglycemia of foetal malnutrition. PMID- 4293971 TI - [Neutralization of MHV-3 hepatitis virus by intestinal tissue of normal mice in presence of bile]. PMID- 4293972 TI - [Culture of the murine hepatitis virus (MHV-3) in monolayer culture of mouse embryo cells]. PMID- 4293973 TI - [Experimental studies on narrow-passage syndrome of peripheral nerves]. PMID- 4293975 TI - Plasticizers in medical application. I. Analysis and toxicity evaluation of dialkyl benzenedicarboxylates. PMID- 4293976 TI - [Typing of Clostridium welchii. 1. Re-evaluation of the agglutination method]. PMID- 4293974 TI - [Cerebrospinal fluid findings, clinical aspects and virus etiology in acute polyneuritis]. PMID- 4293977 TI - Plaque assay of the effects of cytosine arabinoside and 5-iodo-2'-deoxyuridine on the synthesis of H-I virus particles. PMID- 4293978 TI - Organospecificity of liver cell surface antigens and its loss by ascitic hepatoma. PMID- 4293979 TI - [Effect of varying doses of vitamin D 3 on the nature of the osteopathy induced by lack of calcium in the growing rat]. PMID- 4293980 TI - Investigation of albumin metabolism in man. PMID- 4293981 TI - Corticotrophin secretion in patients with head injuries examined by the metopirone test. PMID- 4293983 TI - Molecular pathology and carcinogenesis. PMID- 4293982 TI - [Pituitary corticotropic reserve and cortico-adrenal function in Klinefelter's syndrome]. PMID- 4293984 TI - Some psychologic considerations in the medical management of ulcerative colitis. PMID- 4293985 TI - [Immunohistologic ACTH test in an R-Cell-adenoma of the anterior lobe of the hypophysis in Cushing's disease]. PMID- 4293986 TI - [Hepatic inactivation and pressor action of angiotensin]. PMID- 4293987 TI - [Analysis of information flow in the walk-response of the crayfish Orconectes virilis to abdominal photo-stimulation]. PMID- 4293988 TI - Foot-and-mouth disease. PMID- 4293989 TI - [Pyrexial mechanism in hyperthyroidism]. PMID- 4293990 TI - [The possibility of water-borne dissemination of certain adenovirus infections]. PMID- 4293991 TI - Study uncovers 'unnecessary' long-term stays in a short-term hospital. PMID- 4293992 TI - Activities of various steroidogenic enzymes in two forms of experimental adrenal hyperplasia. PMID- 4293993 TI - Projection of growth. PMID- 4293994 TI - Spectrum of human cytomegalovirus complement-fixing antigens. PMID- 4293995 TI - Rubella virus: role of interferon during infection of African green monkey kidney tissue cultures. PMID- 4293996 TI - Studies on bovine glomeruli. II. Localization of glomerular collagen. PMID- 4293997 TI - [Determination of antibody inhibited and noninhibited serum insulin activity in obesity and the reaction following intravenous glucose administration]. PMID- 4293999 TI - [Internal treatment of hyperthyroidism with potassium perchlorate]. PMID- 4293998 TI - Experimental study on chronic viral hepatitis in mice. PMID- 4294000 TI - Muscular dystrophy associated with intermittent peripheral neuropathy. PMID- 4294001 TI - [Comparative cytochemistry and ultrastructure of synovial fluid inclusions in various forms of inflammatory rheumatism]. PMID- 4294002 TI - [Value of the demonstration of crystalline formations in the synovial fluid: the morphologic and ultrastructural differentiation of the crystals]. PMID- 4294003 TI - [Intestinal absorption of vitamin D3-H3 in 16 cases of osteomalacia]. PMID- 4294005 TI - [Pleural manifestations of malignant lymphoreticulopathies]. PMID- 4294004 TI - [The results of purely medical treatment of Pott's disease in adults]. PMID- 4294006 TI - A new fixative and technics for the diagnosis of intestinal parasites. PMID- 4294007 TI - Intrauterine and neonatal infections under immature antibody formation system. PMID- 4294008 TI - [Dysgenesis thymicolymphatica and its relation to infection]. PMID- 4294009 TI - Comparison of glycolytic enzyme activities in a series of human and rodent hepatomas. PMID- 4294010 TI - The molecular correlation concept of neoplasia. PMID- 4294011 TI - Benign synovioma. PMID- 4294012 TI - Cushing's syndrome associated with an islet-cell tumour of the pancreas in a boy aged 2 years. PMID- 4294013 TI - Corticosteroid therapy in children with asthma. Hypophyseo-adrenocortical inhibition. PMID- 4294014 TI - Some aspects of cancer in childhood. PMID- 4294015 TI - On the theory of silicosis. 3. Stishovite. PMID- 4294016 TI - [Viral pustulosis on Hailey-Hailey pemphigus]. PMID- 4294017 TI - [Unilateral acropathia ulcero-mutilans]. PMID- 4294018 TI - Food-associated viruses. PMID- 4294019 TI - Clostridium perfringens and other bacterial species as possible causes of foodborne disease outbreaks of undetermined etiology. PMID- 4294020 TI - Estimation of mammalian collagenolytic activity with a synthetic substrate. PMID- 4294021 TI - The effect of nicotinamide adenine dinucleotide and rotenone on the oxidation of choline by rat liver mitochondria. PMID- 4294022 TI - The detection and characterization of several conformational states of cytochrome b5 aporeductase during reversible denaturation. PMID- 4294023 TI - The amino acid sequence of an extracellular nuclease of Staphylococcus aureus. II. The amino acid sequences of tryptic and chymotryptic peptides. PMID- 4294024 TI - The amino acid sequence of an extracellular nuclease of Staphylococcus aureus. 3. Complete amino acid sequence. PMID- 4294025 TI - The interaction of nucleotides with the active site of staphylococcal nuclease. Spectrophotometric studies. PMID- 4294026 TI - An improved method for the purification of staphylococcal nuclease. PMID- 4294027 TI - Pathogenesis of the postcardiotomy syndrome. PMID- 4294028 TI - Granular cell myoblastoma of the oesophagus--a report of 2 cases. PMID- 4294029 TI - Radiography in malignant tumors of paranasal sinuses with beginning exophthalmos. PMID- 4294030 TI - Recurrent Cushing's disease and intermittent functional adrenal cortical insufficiency following subtotal adrenalectomy. PMID- 4294031 TI - Aggressive approach to the treatment of Wilms' tumor. PMID- 4294032 TI - [Interaction between pigments and nucleic acids. 3. In vitro inhibition of the functioning of E. coli RNA polymerase by luteoskyrine]. PMID- 4294033 TI - [Methods for preparation of phosphatidic acids. 1. Extraction and purification of wheat germ phosphatidic acid]. PMID- 4294034 TI - [Exaggeration of the pressor response to angiotensin in a case of adrenal pheochromocytoma]. PMID- 4294035 TI - Febrile mucocutaneous syndrome with respiratory involvement, associated with isolation of Mycoplasma pneumoniae. PMID- 4294036 TI - Lipid cell tumors of the ovary. PMID- 4294037 TI - Neurogenous tumors of the head and neck. PMID- 4294038 TI - Multiple granular cell tumors ("myoblastomas"). Case report with electron microscopic observations and review of the literature. PMID- 4294039 TI - [ACTH]. PMID- 4294040 TI - The determination of the urinary excretion of 11-oxy-17-ketosteroids in normal human individuals and in patients with rheumatoid arthritis. PMID- 4294041 TI - Intranuclear inclusion disease of pigeons. PMID- 4294042 TI - Studies on cytochrome a. XVII. Analogy and distinction between the cyanide complex and the so-called "cytochrome a" free from cytochrome a3. PMID- 4294043 TI - The effect of rotenone on the regulation of fatty acid synthesis in heart mitochondria. PMID- 4294044 TI - The isolation of 4-thiouridylate disulfide from oxidized transfer ribonucleic acid of Escherichia coli. PMID- 4294045 TI - Purification and properties of chicken liver xanthine dehydrogenase. PMID- 4294046 TI - Differential effects of palmityl coenzyme A on liver microsomal inorganic pyrophosphate-glucose phosphotransferase and glucose 6-phosphate phosphohydrolase. PMID- 4294047 TI - Models for cooperative effects in proteins containing subunits. Effects of two interacting ligands. PMID- 4294048 TI - Enzymatic breadage and joining of deoxyribonucleic acid. 3. An enzyme-adenylate intermediate in the polynucleotide ligase reaction. PMID- 4294049 TI - On the subunit structure of ribonucleoside diphosphate reductase. PMID- 4294050 TI - The reaction of liver alcohol dehydrogenase with reduced diphosphopyridine nucleotide. PMID- 4294051 TI - Radioautography with tritiated thymidine in measles and Sendai virus-induced chromosome pulverizations. PMID- 4294052 TI - Radioimmunoassay of beta-MSH in human plasma and tissues. AB - A radioimmunoassay method for beta-melanocyte-stimulating hormone (beta-MSH) has been developed and utilized in the identification and quantification of this hormone in human plasma and tissues. The concentration of beta-MSH in two human pituitary glands was found to be approximately 350 mug/g. beta-MSH was identified in the tumor tissue of all 11 patients with the ectopic ACTH syndrome who were studied; concentrations in individual cases ranged from 3 to 1600 ng/g. In plasma of chronically hyperpigmented patients with Addison's disease, Cushing's disease (after bilateral adrenalectomy), and the ectopic ACTH syndrome, beta-MSH concentrations of 0.5-6 ng/ml were found. The degree of clinical hyperpigmentation was well correlated with the quantity of beta-MSH in the plasma. beta-MSH concentrations in the plasma of normal subjects were less than 0.09 ng/ml. In all of these circumstances, bioassays for MSH were also performed, and it was found that most of the biologic MSH activity of the plasma and tissues could be accounted for by beta-MSH. PMID- 4294053 TI - Effects of adrenergic receptor activation and blockade on the systolic preejection period, heart rate, and arterial pressure in man. AB - We have investigated the possibility that alterations in the duration of the systolic preejection period can be used to estimate adrenergic influences on the human left ventricle. The preejection period was determined from high speed, simultaneous recordings of the phonocardiogram, carotid pulse tracing, and electrocardiogram. The preejection period was shortened by isoproterenol, epinephrine, and moderate doses of norepinephrine-all of which activate beta adrenergic receptors-and by cedilanid-D. It was unaltered by changes in heart rate induced by atropine and right atrial electrical pacing. Beta adrenergic receptor blockade by propranolol abolished the shortening effects of the three catecholamines but did not inhibit that due to cedilanid-D. Vasoconstriction, both alpha adrenergic (epinephrine and norepinephrine after propranolol) and nonadrenergic (angiotensin), prolonged the preejection period. Most of the shortening of the preejection period by beta adrenergic receptor activating agents and cedilanid-D and all of the prolongation accompanying pharmacologic vasoconstriction occurred after the onset of the first heart sound, thereby excluding changes in electrical-mechanical delay as a major factor in the observed preejection period responses. Shortening of the preejection period by beta adrenergic activity induced with isoproterenol was dose-related. Increasing doses of propranolol produced parallel shifts to the right in the isoproterenol dose-response curve. In 37 normal resting subjects intravenous propranolol (10 mg) prolonged the preejection period an average of 10 (SE +/- 1) msec. In six patients with psychogenic sinus tachycardia and a patient with a pheochromocytoma the presence of excessive beta adrenergic influences on the left ventricle was demonstrated by the finding of an initially short preejection period which responded with an abnormally great prolongation to beta adrenergic receptor blockade. PMID- 4294054 TI - A possible role for the adenylcyclase system in insulin secretion. AB - A possible role for adenylcyclase in insulin secretion was investigated. Isoproterenol, a predominantly beta-adrenergic agent, when mixed with an alpha adrenergic blocking agent (phenoxybenzamine), stimulated insulin secretion from pieces of the rat's pancreas in vitro. Theophylline, caffeine, 3'5'-cyclic AMP, glucagon, adrenocorticotropin (ACTH), and thyrotropin (TSH), all of which are thought to act through the adenylcyclase systems in the liver and adipose tissue, also stimulated insulin secretion in vitro; oxytocin and vasopressin, which do not stimulate lipolysis in adipose tissue, were inactive. In all cases, stimulation of insulin secretion could not be detected when glucose was absent or present in only low concentrations (less than 100 mg/100 ml) and was maximal at high levels of glucose (300 mg/100 ml). When pancreatic tissue was obtained from normoglycemic rats and contained no detectable glycogen in the Islets, the stimulant effects of glucose and of theophylline were reduced or abolished by mannoheptulose and 2-deoxyglucose. When tissue was derived from rats infused for 8-10 hr with glucose and contained glycogen, theophylline, even in the absence of glucose, stimulated secretion and this effect was reduced by 2-deoxyglucose but not by mannoheptulose. It is suggested that the beta-cell contains an adenylcyclase system through which phosphorylase and possibly phosphofructokinase could be activated; and that insulin secretion could depend upon and be regulated by hormones and other substances which influence the rate at which glycolysis proceeds within the beta-cell. PMID- 4294055 TI - Cytochrome oxidase repair during treatment of copper deficiency: relation to mitochondrial turnover. AB - The repair of cytochrome oxidase depletion during the treatment of copper deficiency was studied in the rat. The purpose of this study was to distinguish the role of new cell production from the possibly more specific role of mitochondrial turnover in determining the rate of this repair. In rats on a copper-deficient regimen until 2.5-3 months of age, activities of cytochrome oxidase expressed as per cent of control were as follows: skeletal muscle (quadratus lumborum), 18%; heart, 27%; liver, 34%; and intestinal mucosa, 34%. After 2-3 days of dietary supplementation with cupric acetate, repair of decreased cytochrome oxidase activity in intestinal mucosa is complete. Histochemical studies indicated that this repair starts in the newly differentiating cells at the base of the villus and then progresses toward the tip of the villus at a rate approximating the normal rate of migration of the mucosal cells. In liver and skeletal muscle, cytochrome oxidase activity returned to control values after 10-15 days of treatment with cupric acetate. In heart muscle, control values were approached more slowly as indicated both by activity of the enzyme and by mitochondrial difference spectra which reflect enzyme concentration. Although cytochrome oxidase repair in the intestine appeared to be limited by the rate of production of new mucosal cells, the rate of repair in liver and skeletal muscle was several times too rapid to be accounted for by known rates of new cell production. Incorporation of tritiated thymidine into DNA in these tissues in both the deficiency state and during repair indicated no major differences in new cell production compared to that of control animals. However, the time required for cytochrome oxidase repair in liver was similar to the turnover reported for other mitochondrial constituents in this tissue. The rate of cytochrome oxidase repair may therefore be more directly determined by the rate of synthesis of new mitochondrial material than by the rate of production of new cells. PMID- 4294056 TI - Inhibition of the activity of alpha-toxin of Clostridium perfringens by toxic filtrates of corynebacteria. PMID- 4294057 TI - The presence of ECHO 9 antibodies in the young population of different regions in Serbia. PMID- 4294058 TI - The isolation of cytopathogenic enteroviruses from the sewage in Moscow and the Moscov District in 1963-1964. PMID- 4294059 TI - Treatment of pulmonary tuberculosis. PMID- 4294060 TI - Irradiation stricture of small and large intestine simulating recurrence of neoplasm. PMID- 4294061 TI - Inhibitory action of sodium ions on transmitter release at the motor end-plate. PMID- 4294062 TI - Urinary excitatory postsynaptic potentials in Clarke's column neurons. PMID- 4294063 TI - Influence of denervation on localization of neurotoxins from clapid venoms in rat diaphragm. PMID- 4294064 TI - Effect of chlordiazepoxide on stomach ulcers in rabbit induced by stress. PMID- 4294065 TI - Association of AAV-1 with simian adenoviruses. PMID- 4294066 TI - Incorporation of C14-choline and tritiated inositol into rat adipose tissue phospholipid in vitro. PMID- 4294067 TI - Mechanism of the toxic effects of hyperbaric oxygen. PMID- 4294068 TI - Adrenergic innervation of the human female reproductive organs: a histochemical and chemical investigation. PMID- 4294069 TI - [Experimental studies on the enzymatic content of the lyophilized thymus]. PMID- 4294070 TI - The biochemical development of surface activity in mammalian lung. I. The surface active phospholipids; the separation and distribution of surface-active lecithin in the lung of the developing rabbit fetus. PMID- 4294071 TI - [The effect of an angiotensin infusion on human urine concentration under maximal ADH-effect]. PMID- 4294073 TI - [Arteriographic study of a glomus jugulare tumor. Importance of selective angiography of the external carotid]. PMID- 4294072 TI - Tar and grease removal from injured parts. PMID- 4294074 TI - The murine leukemia-sarcoma virus complex. PMID- 4294076 TI - [Pathogenesis of juvenile diabetes and diabetes in the adult]. PMID- 4294077 TI - [Selective arteriography in cancer of the rectum]. PMID- 4294075 TI - [Contribution to the pharmacologic study of some sulfur derivatives of trisubstituted orthophosphoric acid. II. Toxicity trials]. PMID- 4294079 TI - [Erection of the gallbladder during Boyden's test in frontal and lateral, timed, accelerated cholecystography]. PMID- 4294078 TI - [Diagnostic contribution of selective arteriography of the celiac trunk in some cases of benign or malignant thickening of the gastric mucosa. (Large-fold gastropathies, systemic elastorrhexis, gastric hypertrophy of the folds of the cardial infundibulum, epithelioma of the esophagogastric juncture)]. PMID- 4294080 TI - [Klinefelter's polygonosomy and achondroplasia]. PMID- 4294081 TI - [Services rendered by tomography in the diagnosis of osteochondritis dissecans of the knee]. PMID- 4294082 TI - [A case of Bowen's anorectal cancer. Presentation of a case of spino-cellular, perianal Bowen's cancer with a baso-cellular Bowen's intrarectal lesion. Report of histological studies]. PMID- 4294083 TI - [Pulmonary sites of the sclerodermias]. PMID- 4294084 TI - [Study of body composition with the aid of radioisotopes in normal human beings, and in various pathologic states. Method]. PMID- 4294085 TI - [Current therapy of functional uterine hemorrhages]. PMID- 4294086 TI - [Chronic osteomyelitis...little known disease]. PMID- 4294087 TI - [Perforation of the rectum during a barium enema]. PMID- 4294089 TI - [The polygraphic syndrome. Its definition. Its spontaneous or induced modifications]. PMID- 4294088 TI - [Juvenile hepato-renal polycystitis. Apropos of a case disclosed by an episode of renal insufficiency with asystole]. PMID- 4294091 TI - [Myositis ossificans]. PMID- 4294090 TI - [Study of hepatic function by galactose and bromosulfophthalein: their reciprocal interference]. PMID- 4294092 TI - [Urinary stress incontinence in women]. PMID- 4294093 TI - [Microbial diarrhea in infants]. PMID- 4294094 TI - [Hypophysiolysis, diabetic retinopathy and cancer of the breast]. PMID- 4294095 TI - [Apropos of 60 cases of paralytic sciatica]. PMID- 4294096 TI - [Concentrated radiotherapy: immediate results in the first 200 cases]. PMID- 4294097 TI - [Piperazine and renal lithiasis]. PMID- 4294098 TI - [Classification of the hyponatremias. Value of measurement of exchangeable sodium and potassium]. PMID- 4294099 TI - [Hyperestrogenism in cirrhosis. Chromatographic study and the estradiol benzoate loading test]. PMID- 4294100 TI - [Purulent Bacillus cereus pleurisy in an asthmatic patient treated for a long time with corticoids]. PMID- 4294101 TI - Cryosurgery in otolaryngology. PMID- 4294102 TI - [Studies on the diagnostic significance of serum anti-streptococcal diphosphoryridine nucleotidase in streptococcal infections. 1. Its values in normal children]. PMID- 4294103 TI - [Studies on the diagnostic significance of serum anti-streptococcal diphosphopyridine nucleotidase in streptococcal infections. 2. Its values in various pediatric diseases]. PMID- 4294104 TI - Mechanism of ribulose-diphosphate carboxydismutase reaction. PMID- 4294105 TI - [Histogenesis of various skin appendage tumors in the ligh of histochemical and electron microscopical findings (eccrine poroma, eccrine spiradenoma, syringoma, cylindroma and calcified epithelioma)]. PMID- 4294106 TI - In vitro cultivation and immunofluorescent studies of transplantable carcinomas Vx2 and Vx7. Persistence of a Shope virus-related antigenic substance in the cells of both tumors. AB - The Vx2 and Vx7 rabbit carcinomas, both of Shope papilloma derivation, were cultivated in vitro and studied for immunofluorescence indicative of the presence of viral antigen. The cultured Vx7 cells were characteristically pleomorphic, round or polygonal cells, and immunofluorescence was demonstrable in 5-20% of them as counted on cover slip cultures after exposure to rabbit sera containing anti-Shope papilloma virus antibody. The Vx2 cells in contrast to this were of almost uniform size and character, small and approximately round, and the specific fluorescence was found in less than 0.1% of the total number. These findings indicate that some antigenic derivation from the Shope papilloma virus is still persisting at least in some fractions of the cells, not only of Vx7 tumors but also of the Vx2 tumors, even after maintenance of the growths by transplantation for more than 20 yr. During the course of the study, two lines of the Vx7 were kept continually growing while the culture of Vx2 was discontinued at its tenth passage after an accident due to mechanical failure of the incubator. The neoplastic capacity of the Vx7 cells cultured in vitro was demonstrated by implanting these intradermally on the ears of domestic rabbits. The result was destructive carcinomas of the Vx7 sort. PMID- 4294107 TI - Studies on the mode of action of diphtheria toxin. 3. Site of toxin action in cell-free extracts. AB - Extracts from HeLa cells treated with excess diphtheria toxin for several hours, until all protein synthesis has been arrested, are still able to stimulate the poly U-directed incorporation of phenylalanine into polypeptides at a moderate rate. Activity may be restored to normal levels or above by addition of a soluble enzyme fraction containing transferase II. Our results are in agreement with those of Collier who has recently shown that toxin inactivates transferase II in extracts from rabbit reticulocytes. We have further demonstrated that amino acid incorporation in extracts from intoxicated HeLa cells is limited by their transferase II content whereas, in extracts from normal cells, it is the ribosomes and to a lesser extent sRNA that are limiting. We have found that only soluble transferase II is inactivated by toxin; the ribosome-bound enzyme is resistant. PMID- 4294108 TI - Studies on the mode of action of diphtheria toxin. IV. Specificity of the cofactor (NAD) requirement for toxin action in cell-free systems. AB - The ability of a number of nucleotides related to NAD to replace NAD as cofactors for inhibition by diphtheria toxin of peptide bond formation has been examined. Neither NADH nor NADP are active. Of some 14 analogues closely related structurally to NAD that have been tested, only 3-thiocarboxamide pyridine-AD is as active as NAD itself. Replacement of the 3-carboxamide group on the pyridine ring by an acetyl group, or deamination of the purine ring, resulted in derivatives with reduced activity. The results were interpreted as suggesting that NAD and certain related nucleotides are capable of specific interaction with diphtheria toxin. Using the method of equilibrium dialysis, reversible binding of 1 mole of NAD per mole of toxin has been demonstrated. Toxoid does not interact with NAD. PMID- 4294109 TI - Studies on the mode of action of diphtheria toxin. V. Inhibition of peptide bond formation by toxin and NAD in cell-free systems and its reversal by nicotinamide. AB - Inhibition of soluble transferase II activity in cell-free systems by diphtheria toxin and NAD can be prevented or reversed in the presence of a sufficient concentration of nicotinamide. Quantitative studies on inhibition of peptide bond formation in cell-free extracts by toxin and NAD have indicated that two successive reversible reactions are involved. First, toxin and NAD interact mole for mole to form a relatively dissociable complex. This toxin-NAD complex then reacts with transferase II to form an enzymatically inactive product that is but slightly dissociated. In the presence of sufficient nicotinamide, however, the latter complex can be broken down to yield active transferase II once more. Based on the above model, an equation has been derived that accurately predicts the per cent inhibition of amino acid incorporation in cell-free systems at any given toxin and NAD level. The observed inhibition appears to be independent of the sensitivity to toxin of the cell species from which the extracts were derived, and depends only on the toxin and NAD concentrations. Although the model satisfactorily explains inhibition of peptide bond formation by toxin in cell free systems, further assumptions are needed to explain how still lower concentrations of toxin are able to arrest protein synthesis completely in the living cell. PMID- 4294110 TI - Evaluation of ascorbic acid as an adrenal scanning agent. PMID- 4294111 TI - Thymic function and carcinogenesis. PMID- 4294112 TI - Psychotropic drugs and neurohumoral substances in the central nervous system. PMID- 4294113 TI - The effect of vitamin A on myxoviruses. II. Alterations in the lipids of influenza virus. PMID- 4294114 TI - Group-specific antigen of avian leukosis viruses. Virus specificity and relation to an antigen contained in Rous mammalian tumor cells. PMID- 4294115 TI - Enhanced diffusion of enterovirus antigens in agar gel in the presence of protamine. PMID- 4294116 TI - Angiographic diagnosis of the character of cerebral gliomas. PMID- 4294117 TI - Studies on the use of ACTH in multiple sclerosis. PMID- 4294118 TI - Renal function during exercise. With special reference to exercise proteinuria and the release of renin. PMID- 4294119 TI - Enzymes of the accessory boring organ of the muricid gastropod Urosalpinx cinerea follyensis. I. Aerobic and related oxidative systems. PMID- 4294120 TI - [Isolation of rhinoviruses on human embryonic fibroblasts]. PMID- 4294121 TI - [Paraganglioma of the middle ear]. PMID- 4294122 TI - Cardiac effects of hayatin methochloride & other histamine releasers. PMID- 4294123 TI - Medical quackery. PMID- 4294124 TI - [Mammary cancer in experimental animals with special reference to mouse mammary cancer]. PMID- 4294125 TI - [Case of surgery of palate cancer]. PMID- 4294126 TI - [Contribution to the histochemical study of the human palatine tonsil]. PMID- 4294127 TI - Isotopic determination of histidine decarboxylase: a disposable assay vial. PMID- 4294128 TI - Studies with a multichannel flame spectrometer. 3. Simultaneous analysis of magnesium, calcium, copper, manganese, and chromium: a method devoid of cation and anion interferences. PMID- 4294129 TI - [Demonstration in quail embryo cell cultures of a latent virus, cytopathogenic and tumorigenic for quail and chicks. Relationships between this virus and Rous sarcoma virus]. PMID- 4294130 TI - Hydrogen transfer into mitochondria in the metabolism of ethanol. I. Oxidation of extramitochondrial reduced nicotinamide-adenine dinucleotide by mitochondria. PMID- 4294131 TI - [Puncture cytology in ORL and cervico-facial pathology]. PMID- 4294132 TI - Kethyl activation and sRNA methylation by soluble fractions of several vertebrate livers. PMID- 4294133 TI - Ferrous iron oxidation by Ferrobacillus ferrooxidans. Purification and properties of Fe++-cytochrome c reductase. PMID- 4294134 TI - Mechanism of Fe++-cytochrome c reductase of Ferrobacillus ferrooxidans. PMID- 4294135 TI - New 1,2-disubstituted benzimidazoles with high inhibiting effects on poliovirus replication. PMID- 4294136 TI - The effect of ammonium ion upon ribonucleic acid polymerase and guanidine triphosphatase activity in isolated bovine endometrial nuclei. PMID- 4294137 TI - The oxidation-reduction state of pyridine nucleotide in isolated frog gastric mucosa. PMID- 4294138 TI - Metabolism of pyridoxal phosphate in the liver of hypo- and hyperthyroid rats. PMID- 4294140 TI - Virogenic lines of RSV-transformed rat cells. PMID- 4294139 TI - Increased pressor responsiveness to kidney extracts. PMID- 4294141 TI - Influence of heavy water (D2O) on the multiplication of adeno and Mengo virus. PMID- 4294142 TI - [Study on the uptake of choline and acetylcholine in the brain]. PMID- 4294143 TI - The aldosterone-renin constellation in Conn's syndrome. PMID- 4294144 TI - Congenital malformation of the heart with inclusion body disease--report of four autopsy cases. PMID- 4294145 TI - [Ribonucleases, phosphodiesterases and phosphomonoesterases in the culture of Neurospora crassa under various conditions]. PMID- 4294146 TI - Median and ulnar neuropathy in the guinea-pig. PMID- 4294147 TI - Phrenic nerve conduction in man. PMID- 4294148 TI - Experimental vascular lesions elicited by collagenase in rats. PMID- 4294149 TI - [Biochemical study on the host response to tuberculous infection. 3. Significance of live tubercle bacilli to the metabolic changes of host]. PMID- 4294150 TI - [Paget's disease as a special form of cancer of the mammary glands]. PMID- 4294151 TI - Electronic aspects of carcinogenesis. PMID- 4294152 TI - Biological and physical properties of leukemogenic agent of a new type of viral murine leukaemia. 1. Sensitivity of other mouse strains and other species to the virus, titration of the virus, influence of a temperature on leukemogenic activity. PMID- 4294153 TI - Serum and liver beta-glucuronidase activity in the course of experimental hepatocancerogenesis induced by diethylnitrosamine in mice. PMID- 4294154 TI - [Vasopressor drugs in shock due to myocardial infarction]. PMID- 4294155 TI - The rhinoviruses. PMID- 4294156 TI - [New studies on the deactivation of DDT on clay surfaces]. PMID- 4294157 TI - [Study of intestinal absorption in the malnourished. 3. 1. Lipiodol test in the study of intestinal absorption in the malnourished]. PMID- 4294158 TI - [Evaluation of the secretory capacity of ACTH by the pituitary with metyrapone in patients with amenorrhea]. PMID- 4294159 TI - [Differences between the biochemical structure of the bacterium W. perifringens A and its toxin]. PMID- 4294160 TI - [Complications and side effects of hormonal therapy in children]. PMID- 4294161 TI - [Differential diagnosis of non-icteric forms of infectious hepatitis and adenovirus diseases]. PMID- 4294162 TI - [Disorders of the peripheral circulation in lumbosacral radiculitis syndromes]. PMID- 4294163 TI - [The effect of microwave therapy on vascular reactions in patients with lumbosacral radiculitis]. PMID- 4294164 TI - [The effect of toxic substances on the functional status of the adrenal cortex]. PMID- 4294165 TI - [On the effect of urethane on carbohydrate metabolism]. PMID- 4294166 TI - [On the inhibition of mitochondrial NADH2 oxidation by D,L-palmitoylcarnitine]. PMID- 4294167 TI - [Chromatography of nucleic acids of normal rat liver nuclei on methylated albumin kieselguhr columns]. PMID- 4294168 TI - [Case of Cushing's syndrome presenting a shock symptom by ACTH-Z after adrenalectomy and the skin reaction to ACTH-Z in children]. PMID- 4294169 TI - [Enzyme histochemical studies of malignant tumors in childhood. 2. Enzyme histochemical study on beta-glucuronidase and amylophosphorylase in acute leukemia]. PMID- 4294170 TI - Radiolysis of solid L-alpha-alanine. PMID- 4294171 TI - Electron spin resonance spectra of an irradiated single crystal of L-alpha alanine at 77K. PMID- 4294172 TI - [Extra-adrenal interference of corticotropin with kinetics and biotransformation of cortisol in man]. PMID- 4294173 TI - Magnetic resonance studies of met-myoglobin and myoglobin azide. PMID- 4294174 TI - [Control of viral hepatitis]. PMID- 4294175 TI - [Determination of epichlorohydrin in the air]. PMID- 4294176 TI - [Hormone-producing tumors]. PMID- 4294177 TI - [Distribution of certain enzymes in the normal mucosa of the human small intestine]. PMID- 4294178 TI - [Specificity and heterogenicity of enzymes]. PMID- 4294179 TI - [Studies on the level of antibodies against parainfluenza type 3 virus]. PMID- 4294180 TI - [Food poisoning caused by Clostridium perfringens]. PMID- 4294181 TI - [Sarcomatous hamartoma of the kidney]. PMID- 4294183 TI - [Effect of ACTH on hyperbilirubinemia in newborn infants]. PMID- 4294182 TI - Spermatogenesis in animals as revealed by electron microscopy. XVI. The microtubular structure and sites of thiamine pyrophosphatase activity in premature sperm of the Japanese crayfish. PMID- 4294184 TI - Effect of enhancer on the replication of newcastle disease virus in chorioallantoic membranes. PMID- 4294185 TI - The structure of infectious bovine rhinotracheitis virus. PMID- 4294186 TI - [Type I poliomyelitis epidemic in France and use of homotypic vaccine (Sabin LSc 2ab) by oral administration. 1. Virological and serological study of clinical cases and viral spread in schools and the environment of patients before oral vaccination]. PMID- 4294188 TI - [Type I poliomyelitis epidemic in France and use of homotypic vaccine (Sabin LSc 2ab). 3. Study of the non-poliomyelitic enteric virus isolated before and after vaccination. Predominance of Coxsackie A7 virus]. PMID- 4294187 TI - [Type I poliomyelitis epidemic in France and use of homotypic vaccine (Sabin I LSc 2 ab) by oral administration. II. Study of the results of vaccination. Characterization of the virus eliminated by the vaccines]. PMID- 4294189 TI - [Use of acetonitrile in thin-layer chromatography on silica impregnated with silver nitrate (laboratory note)]. PMID- 4294190 TI - [Thin-layer chromatography on silica gel-active carbon. Separation of saturated fatty acids and their methyl esters]. PMID- 4294191 TI - [The most common malignant tumors of the uterus: endometrial carcinoma, sarcoma, chorioadenoma, choriocarcinoma, clinical and therapeutic management]. PMID- 4294192 TI - Complement-fixing antibodies in mammals bearing Rous sarcoma. PMID- 4294193 TI - Properties of ATP-ase of the BAI strain A virus. I. Characterization of the enzyme from the point of view of activation and inhibition, and a comparison of its properties with those of ATP-ases of the structural components of the leukaemic myeloblast. PMID- 4294194 TI - Properties of ATP-ase of the BAI strain A virus. II. Properties of binding of ATP ase to cell structures and its substrate specificity. PMID- 4294195 TI - [Diseases of the lumbo-sacral portions of the peripheral nervous system in agricultural mechanics]. PMID- 4294196 TI - [Diseases of the peripheral nervous system in lumbermen]. PMID- 4294197 TI - [Modification of hormonal and enzymatic regulations of carbohydrate metabolism by using benzothiadiazines]. PMID- 4294198 TI - The contractile and control sites of natural actomyosin. AB - The various contractile and control sites of natural actomyosin gel were studied by comparing the kinetics of ATP hydrolysis with those of gel contraction, measured as an increase in turbidity. Contraction of actomyosin gel seems to require the cooperative reaction of ATP (with Mg) at two different sites. One of these sites catalyzes the hydrolysis of ATP and most probably contributes the driving force for contraction; the binding of ATP to the other site appears to break certain links that retard movement of the gel components. At limiting concentrations of ATP, the rate of contraction seems to depend on the rate of breaking these links as well as on the rate of ATP hydrolysis. But when both sites are saturated, the rate of contraction appears to be limited only by the rate of ATP hydrolysis. In addition to these two contractile sites, there are also two different control sites. At one, the relaxing site, the binding of ATP with Mg inhibits ATP hydrolysis and gel contraction. At the other, the binding of calcium activates contraction by overcoming the inhibitory action of Mg and ATP at the relaxing site. This control system-inhibition by substrate and disinhibition by calcium-can be selectively inactivated by heat and reactivated by dithiothreitol, a disulfide-reducing agent. These observations on the isolated contractile system are discussed in relation to the contraction and relaxation of muscle. PMID- 4294200 TI - [Lipiodol cisternography in the diagnosis of tumors of the cerebellopontine angle]. PMID- 4294199 TI - The effect of intracellular current pulses in smooth muscle cells of the guinea pig vas deferens at rest and during transmission. AB - The effect of intracellular current pulses on the membrane of smooth muscle cells of the guinea pig vas deferens at rest and during transmission was studied. Two main response types were identified: active response cells, in which a spike was initiated in response to depolarizing currents of sufficient strength and duration; passive response cells, in which depolarizing currents gave only electrotonic potential changes. These cells were three times more numerous than the active response cells. During the crest of the active response the input resistance fell by about 25% of the resting value. Comparison of the active response with the action potential due to stimulating the hypogastric nerve showed that the former was smaller in amplitude and had a slower rate of rise and higher threshold. Electrical coupling occurred between the smooth muscle cells during the propagation of the action potential. Depolarizing current pulses had no effect on the amplitude of the excitatory junction potential (E.J.P.) in passive response cells, but in general did decrease its amplitude in active response cells. These results are discussed with respect to the mechanism of autonomic neuroeffector transmission. PMID- 4294201 TI - [Langerhans tumors of the pancreas (vascular exploration)]. PMID- 4294202 TI - [Treatment of chronic progressive polyarthritis and spondylarthritis ankylopoietica]. PMID- 4294203 TI - [Attempt at an electronystagmographic (ENG) vestibular semiology]. PMID- 4294204 TI - [Vestibular threshold and nystagmic threshold. Value of the study of tonic movements of the eyeballs by recording in continuous current]. PMID- 4294205 TI - [Value of monocular oculography in nystagmography]. PMID- 4294206 TI - [The value of the angiotensin infusion test in differential diagnosis]. PMID- 4294208 TI - [Illustrations of 5 outbreaking carcinomas]. PMID- 4294207 TI - Correlated biochemical, histochemical and electron microscopic studies on fiber types in striated muscles of rat. PMID- 4294209 TI - Shortening-inhibition of prime movers. A safety factor in mastication. PMID- 4294210 TI - Carbon dioxide fixation and phosphoenolpyruvate carboxylase in Ferrobacillus ferrooxidans. PMID- 4294211 TI - [Tumors due to SV 40 virus: reduction of post-operative tumoral recurrences in the hamster by the administration of the virus; resistance to a 2nd transplantation]. PMID- 4294212 TI - Effect of sodium pyrophosphate on experimental soft-tissue calcification and hypercalcemia. PMID- 4294213 TI - Modification of hexobarbital metabolism by Morris hepatoma 5123tc. PMID- 4294214 TI - Oriented overgrowth (epitaxy) of macromolecular organic compounds. PMID- 4294215 TI - [Features specific to the antithyroid action of roentgenographic contrast media]. PMID- 4294216 TI - [Exceptionally diffuse herpetic reinfection of the fulminant type during cortisone treatment of meningococcic meningitis]. PMID- 4294217 TI - [Enzymatic control of gestation development in women treated with ACTH]. PMID- 4294218 TI - On the reduced minus oxidized difference spectrum of P-450 in liver microsomes. PMID- 4294219 TI - Floridean starch of a calcareous red alga, Joculator maximus. PMID- 4294220 TI - Subcellular distribution of P-450 in bovine corpus luteum. PMID- 4294221 TI - Rotenone and amytal insensitive coupled oxidation of NADH by mitochondria from Aspergillus niger. PMID- 4294222 TI - [On the differential diagnosis of keratitis]. PMID- 4294223 TI - [Contribution on the pathogenesis of herpes simplex]. PMID- 4294224 TI - [Cornal infection due to Pseudomonas aeruginosa]. PMID- 4294225 TI - [A difficult to establish cause of death]. PMID- 4294226 TI - [Apropos of a case of glomus jugulare tumor with the jugular foramen syndrome]. PMID- 4294227 TI - Testosterone metabolism by the chicken uropygial gland. PMID- 4294228 TI - Problems related to the determination of the secretion and interconversion of androgens by "urinary" methods. PMID- 4294229 TI - [On the indications for the use of radioiodine (I-131) in thyroid gland cancer therapy]. PMID- 4294230 TI - [Action of angiotensin on parotid secretions]. PMID- 4294231 TI - [The role of active polypeptides in the homeostatic mechanism. On the peripheral chemoreceptive action of antiotensin and oxytocin]. PMID- 4294233 TI - [The study of the disinfecting properties of sodium metasilicate under laboratory conditions and in practice]. PMID- 4294232 TI - [Immunological studies with the desoxycholate extract of Bordetella pertussis according to Barta]. PMID- 4294234 TI - Nycthemeral rhythm of plasma cortisol levels in the Cushing's syndrome associated with hyperplasia of adrenal cortex, before and after treatment of hypophyseal suppression with ultrasonic technique. PMID- 4294235 TI - [Sympathetic nervous system and fat metabolism]. PMID- 4294236 TI - [Morphological investigations of the liver in hormonal influence of the anterior hypophysis-adrenal cortex systems]. PMID- 4294237 TI - [The effect of dimethylbenzanthracenes on the nucleoside triphosphatase activity of amelanotic melanocytes of the hairless mouse]. PMID- 4294238 TI - [Proliferation of the basocellular epithelioma type on histiocytofibromas. (Report of a case)]. PMID- 4294239 TI - [Cutaneous metastases of a muciparous epithelioma]. PMID- 4294240 TI - [Paget's disease of the nipple and mammary epithelioma. Importance of mammography in diagnosis]. PMID- 4294241 TI - [The effect produced by bee venom on certain enzymes and biologically active groups in the tissues of mice in vivo]. PMID- 4294242 TI - Studies on polypeptides. 38. Elimination of the histidine residue as an essential functional unit for biological activity of beta-corticotropin. PMID- 4294243 TI - Spectroscopic models related to coenzymes and base pairs. I. The basis for hypochromism in the ultraviolet spectra of model systems related to nicotinamide- adenine dinucleotide. PMID- 4294244 TI - Electron microscopic examination of subcellular fractions. II. Quantitative analysis of the mitochondrial population isolated from rat liver. AB - Large granule fractions, containing about 80% of the cytochrome oxidase of the tissue, were isolated from rat liver and used to prepare thin pellicles of packed particles which were submitted to quantitative electron microscopic examination. Various parameters describing the mitochondrial population were determined by measuring the size and number of mitochondrial profiles in sections, and the ratio of the inner to the outer membrane area. The mean particle radius and volume were found to be respectively 0.38 micro and 0.29 micro(3); the average areas per mitochondrion were 2 and 5 micro(2) for the outer and inner membranes respectively. On the basis of the cytochrome oxidase activity recovered in the particulate fractions, the results were extrapolated to the whole liver, and it was concluded that rat liver contains about 5.10(11) mitochondria per gram; this corresponds to a volume of 0.14 ml/g and to an area of 2.5 and 1 m(2)/g for the inner and outer membranes respectively. The validity and the accuracy of these determinations is discussed and the results are compared to the information which has been obtained by independent methods or by other investigators. PMID- 4294245 TI - The enzymatic preparation of isolated intact parenchymal cells from rat liver. AB - Suspensions of isolated parenchymal cells were prepared from rat liver by incubation with collagenase and hyaluronidase followed by mechanical treatment. Utilization of 0.15% collagenase together with 0.15% hyaluronidase yielded adequate numbers of cells for experimental purposes. As shown by light and electron microscopy, approximately 75% of the isolated cells retain their structural integrity. The cell suspensions are capable of maintaining endogenous respiration in the presence of 1% albumin for periods of time up to 8 hr. These cell preparations consist almost entirely of parenchymal cells and offer a unique tissue preparation for the study of hepatic metabolism. PMID- 4294246 TI - A study of some motile group D streptococci. PMID- 4294247 TI - [Corticosterone secretion in humans. 3. Secretory rate of corticosterone and cortisol during stimulation of the adrenal cortex with ACTH]. PMID- 4294248 TI - [Studies on leukocyte metabolism. 3. NAD(nicotinamide-adenine dinucleotide) content of isolated leukocytes and the course chronic human leukemia under cytostatic therapy with C 73]. PMID- 4294251 TI - [Smallpox in Kulmbach (1965)]. PMID- 4294250 TI - [Studies of indirect sympathomimetic action of angiotensin on isolated blood vessels]. PMID- 4294249 TI - [Comparative effects of pressor substances in healthy people]. PMID- 4294253 TI - Pleomorphic adenoma. Report of a case. PMID- 4294252 TI - [Primary neoplasms of the thalamus]. PMID- 4294254 TI - Size, score and speed of development of tumors in chickens in response to subcutaneous inoculations with Rous sarcoma virus. PMID- 4294255 TI - The utilization of phytate phosphorus by poultry--a review. PMID- 4294256 TI - Characterization of five isolates of Marek's disease. PMID- 4294258 TI - Pathology of extranasal lesions in experimental inclusion-body rhinitis of pigs. PMID- 4294257 TI - The influence of cortisone and low environmental temperature on experimental infectious canine hepatitis in the guinea-pig. PMID- 4294259 TI - [Low back pain in women. Diagnosis and treatment]. PMID- 4294261 TI - [Alcoholic hypoglycemia. On an observation of a patient with post-gastrectomy deficiency syndrome]. PMID- 4294262 TI - [Cutaneous tuberculosis. Historical, clinical aspects and therapeutic development]. PMID- 4294263 TI - [Combination of pulmonary connective tissue and gastric tumors]. PMID- 4294264 TI - [Nonfamilial ulcero-mutilating acropathy and ossifying periostosis: two cases, one of which is anatomoclinical]. PMID- 4294265 TI - [Viremias and systemic reactions to them; a review]. PMID- 4294266 TI - [The metopirone test for the determination of the hypophysis-adrenal cortex reserve]. PMID- 4294267 TI - [On the effects of ribonuclease on the membrane-bound ribosomes of liver and hepatoma tissue]. PMID- 4294269 TI - Observations on the origin and genesis of a rapid sympathetic rhythm. PMID- 4294268 TI - Some properties of prostaglandin E1 action on muscle. PMID- 4294270 TI - Control of NADH oxidation by ADP in membranes from Mycoplasma laidlawii. PMID- 4294271 TI - Increased protocollagen hydroxylase activity in the livers of rats with hepatic fibrosis. PMID- 4294272 TI - Metabolism of phospholipids. X. Partial purification and properties of a soluble phosphatidate phosphohydrolase from rat liver. PMID- 4294273 TI - Concentrations and disappearance post mortem of polyphosphoinositides in developing rat brain. PMID- 4294274 TI - Polymerization of the adenosine 5'-diphosphate-ribose moiety of nicotinamide adenine dinucleotide by nuclear enzyme. I. Enzymatic reactions. PMID- 4294275 TI - Bovine aorta ribonuclease. PMID- 4294276 TI - Turnover of ribosomal RNA in a ribonuclease I-less mutant of Escherichia coli, Q 13, which was found to possess polynucleotide phosphorylase. PMID- 4294277 TI - Evidence that a rat liver "inhibitor" of the synthesis of DNA in cultured mammalian cells is arginase. PMID- 4294278 TI - [Polynucleotides containing uridine and 4-thiouridine]. PMID- 4294279 TI - [Variations of the level of free plasma corticosterone of the rabbit under the influence of corticotropin and terebenthine]. PMID- 4294280 TI - [Evolution of glycemia in rats ingesting 2 hepatoma-inducing carcinogenic diets]. PMID- 4294281 TI - [Experimental induction of egg laying in Mugil capito confined to fresh water]. PMID- 4294282 TI - Lipids of subcellular particles from bovine heart muscle. I. Fatty acids of neutral lipids. PMID- 4294283 TI - Family interaction in schizophrenia. PMID- 4294285 TI - [Effect of ACTH and some adrenal hormones on the level of the pain threshold]. PMID- 4294284 TI - [Studies on the cellular localization of ACTH secretion in the course of adrenal cortex regeneration in white rats]. PMID- 4294286 TI - [Remarks on the problem of diagnosis of Addison's disease]. PMID- 4294287 TI - Renin content of the rat kidneys after prolonged treatment with formalin or ACTH. PMID- 4294288 TI - Lysosomal damage in various phases of mouse viral hepatitis. PMID- 4294289 TI - Changes in cytochrome oxidase activity of the isolated perfused rabbit kidney. PMID- 4294290 TI - Porcine nephroblastoma. PMID- 4294291 TI - [On our experiences in polyneuropathies]. PMID- 4294292 TI - The synthesis and properties of analogues of angiotensin modified in the 1- or the 4-position. PMID- 4294293 TI - [A case of giant nonfunctional adenoma of the insular tissue of the pancreas]. PMID- 4294294 TI - [Value of laboratory methods in verifying the diagnosis of renovascular hypertension]. PMID- 4294295 TI - [Demonstration of a patient with an ovarian adrenal cell tumor]. PMID- 4294296 TI - [Adrenal cortex function in nephrotic syndrome]. PMID- 4294297 TI - [Public health in the Niayes region (Senegal)]. PMID- 4294298 TI - [Studies on tuberculin allergy among the inhabitants of the Meouane arrondissement]. PMID- 4294299 TI - [Recent data concerning biologic studies in patients with sleeping sickness]. PMID- 4294300 TI - [Necrotic angiodermatitis of the lower limbs and their vascular terrain]. PMID- 4294301 TI - [Clinical trials of ethacrynic acid]. PMID- 4294302 TI - [Effect of castration and administration of estrogens on the activity of some liver enzymes in carbon tetrachloride poisoning]. PMID- 4294303 TI - Acute hemolytic anemia complicating infectious mononucleosis: the mechanism of hemolysis. PMID- 4294304 TI - Histochemistry of the mesonephros in the developing chick. PMID- 4294305 TI - Radiation studies on mice of an inbred tumor-resistant strain. V. Possible evidence for activation of the mammary tumor virus (MTV) by urethane as observed by electron microscopy. PMID- 4294306 TI - Esterase activity in the green alga Trebouxia. PMID- 4294307 TI - Platelet enzymes. PMID- 4294308 TI - [Peculiarities of ATP formation in isolated thymus nuclei]. PMID- 4294310 TI - [Angiographic findings in cerebral spongioblastomas]. PMID- 4294309 TI - [Materials for depth electrodes in neurosurgery and neurophysiology]. PMID- 4294311 TI - Altered synaptic terminals in cortex near tumor. PMID- 4294312 TI - Ocular complications of vincristine therapy. PMID- 4294313 TI - [Demonstration of the biosynthesis in vivo of a compound polymer, polyadenosine diphosphoribose in the nucleus of the liver of chickens]. PMID- 4294314 TI - [Inhibition of the multiplication of foot-and-mouth disease virus in the adult mouse treated previously by Freund's adjuvant]. PMID- 4294315 TI - The effect of gonadectomy on the development of hepatomas induced by urethan. PMID- 4294316 TI - Electron microscopic study of the mouse leukemia virus (Gross) in organs of mouse embryos from virus-injected and normal C3Hf parents. PMID- 4294317 TI - Basophil adenomata in the pituitary glands of 2-year-old male Long-Evans rats. PMID- 4294318 TI - Histologic features of virus-rich and virus-poor Shope papillomas of cottontail rabbits. PMID- 4294320 TI - Tumor production in vivo and cell transformation in vitro by two SV20 strains. PMID- 4294319 TI - Localization of tumor antigens in adenovirus-12-induced tumor cells and in adenovirus-12-infected human and hamster cells by ferritin-labeled antibodies. PMID- 4294321 TI - Hepatocarcinogenicity of griseofulvin following parenteral administration to infant mice. PMID- 4294322 TI - Deoxycytidylate deaminase activity of simian virus 40-infected cell cultures. PMID- 4294323 TI - Vaccarezza's test. Its use in the presumptive diagnosis of cancer. PMID- 4294324 TI - Serum proteins in pulmonary tuberculosis. PMID- 4294325 TI - Carcinoma of the lung in Iceland. PMID- 4294326 TI - Production of steroids by in vitro superfusion of endocrine tissue. I. Apparatus and a suitable analytical method for adrenal steroid output. PMID- 4294327 TI - Cell-sensitizing products of streptococci. PMID- 4294328 TI - Neurohumoral transmission and neuropsychiatric disorders. PMID- 4294329 TI - Pneumonia in the older patient. PMID- 4294330 TI - Enzymatic omega-oxidation. II. Function of rubredoxin as the electron carrier in omega-hydroxylation. PMID- 4294331 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. XV. Reverse electron transfer in the flavin-cytochrome beta region of the respiratory chain of beef heart submitochondrial particles. PMID- 4294332 TI - A requirement for phospholipids by the microsomal reduced diphosphopyridine nucleotide-cytochrome c reductase. PMID- 4294333 TI - A new phosphodiesterase forming nucleoside 5'-monophosphate from rat liver. Its partial purification and substrate specificity for nicotinamide adenine dinucleotide and oligonucleotides. PMID- 4294334 TI - Isolation and properties of a phosphodiesterase from newborn mouse skin. PMID- 4294335 TI - Radiological notes: case no. 292. PMID- 4294336 TI - Experimental studies of intracranial arterial spasm using aortic strip assays. PMID- 4294337 TI - [Biochemical study on the host response to tuberculous infection. 2. NAD-ase of tuberculous mouse]. PMID- 4294338 TI - [Experimental studies of antiperstaltic jejunum transplantation]. PMID- 4294339 TI - [Effect of the autonomic nervous system and adaptive hormones (ACTH and cortisone) on the change in intraocular pressure and outflow from the eye following compression]. PMID- 4294341 TI - Titration patterns of a murine sarcoma-leukemia virus complex: evidence for existence of competent sarcoma virions. AB - Stocks of inurine sarcoma virus show titration patterns ranging from one-to two hit kinetics. The comparison of various titrations of this virus, both with and without added helper virus, to theoretical model systems composed of defined constituents, suggests the existence of a sarcoma virus that does not need coinfectinig murine leukemia virus to be manifested as a focus-forming unit. The behavior of such nondefective particles is compatible with a postulated leukemia sarcoma virus hybrid. PMID- 4294340 TI - Alcohol dehydrogenase of Drosophila: interconversion of isoenzymes. AB - Isoenzymes of alcohol dehydrogenase extracted from Drosophila melanogaster are interconvertible and can be distinguished by electrophoretic mobility. When adsorbed on diethylaminoethyl cellulose, the faster-moving forms are converted to the slowest-moving form; the latter is converted to the former in the presence of 0.05 molar nicotinamide-adenine dinucleotide, and the conversion is accompanied by the binding of 3.5 moles of the dinucleotide per mole of enzyme. A change in heat stability accompanies the conversion of the slowest form of alcohol dehydrogenase to the fastest form; the latter becomes stable at 45 degrees C. The increased heat stability may indicate that a conformational change in the alcohol dehydrogenase occurs along with the binding of nicotinamide-adenine dinucleotide. PMID- 4294343 TI - The sequelae of Japanese encephalitis in Taiwan. PMID- 4294342 TI - Neural communications: experiment and theory. PMID- 4294345 TI - Ultrastructure of trophoblast and endometrium in inasive hydatidiform mole (chorioadenoma destruens). PMID- 4294344 TI - Electron microscopy of human choriocarcinoma transplanted into hamster liver. PMID- 4294346 TI - Back and hip pain in pregnancy due to chordoma. PMID- 4294347 TI - Study of the lungs of fetal and newborn rabbits. Morphologic, biochemical, and surface physical development. PMID- 4294348 TI - Pathogenesis of acute gastric stress ulcers. PMID- 4294349 TI - A colorimetric method for determination of glycols. PMID- 4294350 TI - A pharmacological analysis of ganglionic actions of some general anesthetics. PMID- 4294351 TI - Endocrinology in chronic schizophrenia. PMID- 4294352 TI - [Studies on the elementary particles of the lamellae of the visual cell outer segments. (2). On localization of alcohol-DPN-dependent dehydrogenase of the lamellae]. PMID- 4294353 TI - Tactical radiation dosimetry in the U.S. Army. PMID- 4294354 TI - The charge distribution on the human femur due to load. PMID- 4294355 TI - Alterations in tissue and serum ceruloplasmin concentration associated with inflammation. PMID- 4294356 TI - Kidney injuries in children. PMID- 4294357 TI - Polycystic nephroblastoma. PMID- 4294358 TI - [Effect of cobalt administration on the ultrastructure of mitochondria]. PMID- 4294359 TI - [Effect of regitine on the excretion of 17-hydroxycorticosteroids in healthy subjects and in patients with allergic bronchial asthma]. PMID- 4294360 TI - The concentration of Polyoma virus by ammonium sulfate precipitation and purification by density gradient centrifugation. PMID- 4294361 TI - Sir John Carew Eccles. PMID- 4294362 TI - [Epidemic of acute angina and pharyngitis in a military unit]. PMID- 4294363 TI - [On the behavior of local potentials in stimulation of the motor nerve fibers with rhythmical electrical impulses]. PMID- 4294364 TI - Pathogenicity studies of type I-2 porcine Enterovirus. PMID- 4294365 TI - Immunization experiments on calves with type 4 bovine adenovirus. PMID- 4294366 TI - [The effect of vitamin D3, dihydrotachysterol, and parathormone on alpha-amino nitrogen in the blood of rabbits]. PMID- 4294367 TI - [Hypoglycemic effect of glycodiazine and tolbutamide on rats with normal metabolism, as well as the effect of glycodiazine on the glucose-6-phosphatase of the liver of rats in vitro]. PMID- 4294368 TI - An electron spin resonance signal in brain microsomes. PMID- 4294369 TI - The sub-mitochondrial localization of monoamine oxidase in rat liver and brain. PMID- 4294370 TI - A rapidly labelled RNA associated with DNA in HeLa cells. PMID- 4294371 TI - [1st study of human enteric viruses in Cameroon]. PMID- 4294372 TI - [Description of a 2nd case of phycomycosis in the Ivory Coast with isolation of the strain]. PMID- 4294373 TI - [The relationship between the hydrosaline overload and the natriuretic effect of angiotensin in the rat]. PMID- 4294374 TI - [Isolation of inorganic pyrophosphates from dentin and tooth enamel]. PMID- 4294375 TI - [The effect of val-5-angiotensin II amide and triamterene on urinary acidification in the rat]. PMID- 4294376 TI - [Histological-histochemical studies on the identification of marks caused by electrical current]. PMID- 4294377 TI - Polynucleotidases in animal tissues. PMID- 4294378 TI - [On the question of the genetic change in a rat ascites hepatoma by heterotransplantation in the Chinese hamster]. PMID- 4294379 TI - [Liver cell chondriome in trypsinized culture during gluconeogenesis. Behavior of glucose-6-phosphatase]. PMID- 4294381 TI - [Serologic studies on epidemic keratoconjunctivitis]. PMID- 4294380 TI - [On the problem of the functional status of the hypothalamo-hypophyseal-adrenal system in vibration-induced pathology]. PMID- 4294382 TI - Stable carbonium ions. LX. Protonated alpha,beta-unsaturated carboxylic acids and their cleavage to alkenyloxocarbonium ions. PMID- 4294383 TI - [Myocardial metabolism in hypothermia. 2. Histochemical observation of heart and liver in hypothermia]. PMID- 4294384 TI - [A case of primary mucoepidermoid carcinoma in the submaxillary gland]. PMID- 4294385 TI - [Adenovirus infections in the Croatian SR]. PMID- 4294386 TI - [Common cold caused by the common cold virus and other rhinoviruses]. PMID- 4294387 TI - [The bilateral tarsal tunnel syndrome]. PMID- 4294388 TI - [Indications for steroid therapy in acute trauma in children]. PMID- 4294390 TI - Substitution of egg yolk for serum in indirect fluorescence assay for Rous sarcoma virus antibody. PMID- 4294389 TI - [Role of alloxan diabetes in experimental gas gangrene in white rats]. PMID- 4294391 TI - Variation in adrenal cortical hormones within physiologic ranges, stress and interferon production in mice. PMID- 4294393 TI - [The regularity of the biomorphotic changes in the humeral head in x-rays]. PMID- 4294392 TI - Inhibition of erythropoietic effects of hormones by erythropoietin antisera in mildly plethoric mice. PMID- 4294394 TI - [Hormonal adaptation in the climacteric and the question of hormone therapy in postmenopause]. PMID- 4294395 TI - [Studies of adrenal cortex function in chronic bronchitis under climate therapy in medium and high altitude mountains of Slovakia]. PMID- 4294397 TI - [Contribution on the serological diagnosis of respiratory syncytial virus infections. Comparison of the complement fixation reaction with indirect hemagglutination]. PMID- 4294396 TI - [Experiments of active immunization in hepatitis infectiosa. (Experimental studies on hamsters)]. PMID- 4294398 TI - [Enzyme-histochemical findings in the liver, heart and kidneys of the rat in experimental subtotal potassium deficiency]. PMID- 4294399 TI - On the inhibition of transmission to the dorsal spinocerebellar tract by stretch of various ankle muscles of the cat. PMID- 4294401 TI - [Influence of ACTH on the tryptophan--nicotinic acid pathway in normal subjects and those with rheumatoid arthritis]. PMID- 4294400 TI - The effect of DOPA on the spinal cord. 6. Half-centre organization of interneurones transmitting effects from the flexor reflex afferents. PMID- 4294402 TI - Survival of foot-and-mouth disease virus in bovine hides. PMID- 4294403 TI - Reactions of sheep to cell-culture-modified foot-and-mouth disease virus. PMID- 4294404 TI - Cytomegalic inclusion disease in sand rats (Psammomys obesus): histopathologic evidence. PMID- 4294405 TI - [Effect of certain amino acids on the development of poliovirus]. PMID- 4294406 TI - [Experimental study of murine Yoshida sarcoma]. PMID- 4294407 TI - [3 new Salmonella serotypes isolated in Ivory Coast: S. ebrie=35:g,m,t:-; S. cocody=(8), 20:r,i:e,n,z15; S. adjame=13,23:r:1,6]. PMID- 4294408 TI - [A study on the mechanism of polymyxin M inactivation]. PMID- 4294409 TI - [Therapeutic effect of polymyxin M in experimental endometritis and some gynecological diseases]. PMID- 4294410 TI - [On alveolar carcinoma of the lung]. PMID- 4294411 TI - Foot-and-mouth disease in man. PMID- 4294413 TI - [Phospholipid composition of internal and external mitochondrial membranes]. PMID- 4294412 TI - Foot-and-mouth disease in man. PMID- 4294414 TI - [Sensitivity to pressor agents and hypovolemia]. PMID- 4294415 TI - [Assay of the protective power of polyoma virus against a newly isolated transplantable cellular strain]. PMID- 4294416 TI - [Comparative structure and ultrastructure of tumors initiated by polyoma virus in the golden hamster and maintained by transplantation]. PMID- 4294417 TI - [Effects of acetylcholine at the synaptic and somatic levels in the case of the last abdominal ganglion of the cockroach Periplaneta americana]. PMID- 4294418 TI - [Demonstration of an extra-adrenal effect of corticotropin on the level of liver glycogen and blood glucose in the rabbit]. PMID- 4294419 TI - [Histochemical investigations on the distribution and activity of hydrolytic enzymes in gliomas]. PMID- 4294421 TI - [Variability in the ultra-structure of cancer cells and its biological significance]. PMID- 4294420 TI - Effect of some proteins on the yeast cell membrane. AB - Yeast cells, Candida utilis, in water suspension and in the absence of electrolytes were found to be very sensitive to several proteins of moderate size, including ribonuclease, protamine, lysozyme, bovine serum albumin, cytochrome c, and myoglobin. Viability ceases rapidly, and ultraviolet-absorbing compounds (260 mmu) and the amino acid pool are released into the medium. The ultraviolet-absorbing material appears to be the nucleotide and coenzyme fraction usually extracted by 0.2 n perchloric acid at low temperature. The ribonucleic acid fraction remains in the cell ghosts and can be released by ribonuclease. The enzymatic properties of some of these proteins have no relation to their damaging effect on the cell membrane. Poly-l-lysine shows the same activity. PMID- 4294422 TI - [Malignancy and benignancy in cell culture]. PMID- 4294423 TI - [Clear-cell sarcoma of the patellar tendon]. PMID- 4294424 TI - Lactic dehydrogenase activity in preimplantation rat embryo. PMID- 4294425 TI - Ion movements in junctional transmission. PMID- 4294426 TI - [Inactivation by ozone of poliomyelitis virus present in water. (Further contribution)]. PMID- 4294427 TI - Relationship among nursing frequency, lactation pituitary prolactin, and adrenocorticotropic hormone content in rats. PMID- 4294428 TI - Studies on the mechanism of action of polymyxin B on Cholera vibrios. PMID- 4294429 TI - Effect of thymectomy on rous virus tumor growth induced in chickens. PMID- 4294430 TI - Viruses recovered from laboratory dogs with respiratory disease. PMID- 4294431 TI - ACTH-induced renal glomerular disease in intact, adrenalectomized and castrated male mice. PMID- 4294432 TI - Some chemical and physical characteristics of purified beta-inhibitor from bovine serum. PMID- 4294433 TI - Autoregulation of glucose metabolism in the isolated perfused rat liver. PMID- 4294434 TI - Anterior pituitary levels of FSH, LH, ACTH and prolactin after mating in female rabbits. PMID- 4294435 TI - Comparative susceptibility of neonatal rabbit skin to herpes simplex virus in vitro. PMID- 4294436 TI - Virus infections of the newborn. PMID- 4294437 TI - Analysis of estrogen metabolites by isotope derivative and by fluorimetry. PMID- 4294438 TI - [Radiological estimation of the age of mummified cadaver]. PMID- 4294439 TI - Studies on the possible viral etiology of human breast cancer. PMID- 4294440 TI - The patient, the prescription, the problem: corticosteroid therapy in otorhinolaryngology. PMID- 4294441 TI - [Changes in production and metabolism of cortisol in healthy infants following 3 day depot ACTH administration. I. The urinary excretion of free and glucuronated hormones of the F group]. PMID- 4294442 TI - Circumoval antibodies. Measurement during treatment of experimental schistosomiasis. PMID- 4294443 TI - Mefenamic acid in rheumatoid arthritis. PMID- 4294444 TI - Electron spin resonance study of irradiated bone and its constituents. PMID- 4294445 TI - Studies on the mode of action of isoniazid on mycobacteria. PMID- 4294446 TI - Wurster's blue mediated oxidation of NADH and phosphorylation in mitochondria. PMID- 4294447 TI - Studies on succinate dehydrogenase. 3. Electron-spin resonance measurements at liquid-nitrogen temperature. PMID- 4294448 TI - The enzymatic reduction of ferrihemoglobin. II. Purification of a ferrihemoglobin reductase from human erythrocytes. PMID- 4294450 TI - Studies on rat liver ribonucleases. I. Intracellular localization of the alkal ineribonucleases. PMID- 4294449 TI - Studies on mechanism of inactivation of catechol 1,2-oxygenase by electron spin resonance. PMID- 4294451 TI - Hepatic glycolytic and gluconeogenic enzymes of the obese-hyperglycemic mouse. PMID- 4294452 TI - Nucleoside 5'-O-phosphorothioates as inhibitors for phosphatases. PMID- 4294453 TI - [On the possible presence of a latent salivary gland virus infection in a litter of guinea pigs]. PMID- 4294455 TI - [Clinical aspects of Japanese B encephalitis in the aged]. PMID- 4294454 TI - [Serum protein and its changes in Japanese B encephalitis and in similar diseases]. PMID- 4294456 TI - Blood clearance of the BAI strain A virus of avian myeloblastosis in newly hatched chicks. PMID- 4294457 TI - Use of immunofluorescence for detection of specific membrane antigen in simian virus 40-infected nontransformed cells. PMID- 4294458 TI - Comparative morphologic study of the virus-induced solid tumors of Syrian hamsters. PMID- 4294459 TI - Carcinogenic effects of diethylnitrosamine in RF mice. PMID- 4294460 TI - Electron microscopic identification of viral particles in calcifying epithelioma induced by polyoma virus. PMID- 4294461 TI - Congenital epulis in the newborn: report of 2 cases. PMID- 4294462 TI - Variation in Bordetella pertussis. PMID- 4294463 TI - Pilot-plant experiences in demineralization of secondary effluent using electrodialysis. PMID- 4294464 TI - [Studies on 2-mercaptoethanol sensitivity of the antiserum of Japanese encephalitis virus. (II)]. PMID- 4294465 TI - Control of biochemical expression in morphologically related cells in vivo and in vitro. PMID- 4294466 TI - Histochemical approaches to cell characterization in vitro. PMID- 4294467 TI - Oncogenesis in vitro. PMID- 4294468 TI - "Spontaneous" neoplastic transformation of cells in vitro: some facts and theories. PMID- 4294469 TI - Action of chlorpromazine on non-specific phosphatase bound to membranes in brain tissue of the rat. PMID- 4294470 TI - Function of redox systems in melanophore receptors. PMID- 4294471 TI - Virus-like particles in a human primary hepatocarcinoma. PMID- 4294472 TI - Electron paramagnetic resonance in frozen and dried biological materials. PMID- 4294473 TI - Improved multi-enzyme analyser. PMID- 4294474 TI - Phosphate esters of human erythrocytes: synthesis of ITP-14C from inosine-8-14C. PMID- 4294475 TI - [Case of benign synovioma of the palm]. PMID- 4294476 TI - [Malignant tumor of the hand]. PMID- 4294477 TI - [Several cases of bone tumors of the hand]. PMID- 4294478 TI - Free-radical distributions in several gamma-irradiated dry proteins as determined by the free-radical interceptor technique. PMID- 4294479 TI - Effect of oxygen on radiation-induced free radicals in proteins. PMID- 4294480 TI - [Electron microscopic observations on generalized cytomegalic inclusion disease in an adult--report of an autopsy case]. PMID- 4294481 TI - Specific inhibition of viral ribonucleic acid replication by Gliotoxin. AB - Gliotoxin inhibits intracellular replication of poliovirus in HeLa cells at a stage subsequent to adsorption and penetration of virus. The sensitive step is synthesis of viral RNA: synthesis of viral protein is unaffected except as a consequence of blockade of RNA synthesis. Concentrations of gliotoxin sufficient to block viral RNA synthesis completely do not affect cellular RNA synthesis. PMID- 4294482 TI - Parathyroid hormone production in vitro by human parathyroid cells transformed by Simian virus 40. AB - Cells froma human parathyroid adenoma were infected with simian virus 40 and maintained through 13 subcultures in monolayer tissue culture. For more than 9 months, these "transformed" cells contimed to produce parathyroid hormone which was identified by radioimmunoassay and density-gradient ultra centrifugation. PMID- 4294483 TI - [Technic of removal of mixed tumors of the parotid with parapharyngeal development. Apropos of 3 recent cases]. PMID- 4294484 TI - [Rare tumors of the parotid gland]. PMID- 4294485 TI - [Primary blastomas of the major and minor salivary glands]. PMID- 4294486 TI - Acute necrotizing colitis. PMID- 4294487 TI - Insulin-secreting islet-cell tumours of the pancreas. PMID- 4294488 TI - Recent applications of electron spin resonance in biochemistry. PMID- 4294489 TI - Synthesis of [5-isoleucine, 8-alanine]-angiotensin II by the solution method synthesis and the solid-phase method synthesis. PMID- 4294490 TI - Changes in the properties of human erythrocyte membrane protein after solubilization by butanol extraction. PMID- 4294491 TI - Photochemistry of biological molecules. I. Photolysis of amino acids in the solid state. PMID- 4294492 TI - The syntheses and biological activities of [gly-11, 12,13]-alpha-ACTH(1-9) nonadecapeptide, [gly-12,13] -alpha-ACTH-(1-17)-heptadecapeptide amide, [gly 11,13]-alphaACTH-(1-17)-heptadecapeptide amide, and [gly-13]-alpha-ACTH-(1-17) heptadecapeptide amide. PMID- 4294494 TI - [Study of the protein synthesis in the liver of mice during experimental hepatitis induced with Craig's MHV-3]. PMID- 4294493 TI - Changes in EPR spectra of M-type abnormal haemoglobins induced by deoxygenation and their implications for the haem-haem interaction. PMID- 4294495 TI - [Gas-chromatographic studies of the behavior of urinary 17-ketosteroids, pregnanediol and pregnanetriol before and after stimulation with ACTH and after dexamethasone-induced depression and stimulation with LH (Jayle test) in normal subjects]. PMID- 4294496 TI - [Behavior of the gas-chromatographic fractions of urinary 17-ketosteroids, pregnanediol and pregnanetriol after stimulation with ACTH in hirsutism]. PMID- 4294497 TI - Diseases caused by cytomegaloviruses. PMID- 4294498 TI - Renin-angiotensin-aldosterone system during chronic thiazide therapy of benign hypertension. PMID- 4294499 TI - The effect of ACTH and cortisone on the behaviour of mucopolysaccharides in the glands of the rat stomach. PMID- 4294500 TI - Clinical notes on new methods in the treatment of renal tumors. PMID- 4294501 TI - Retroperitoneal teratoma with nephroblastic tissue as the main component. PMID- 4294502 TI - Electrocardiographic moniteering of patients of shock on angiotensin and noradrenaline therapy. PMID- 4294503 TI - Incorporation of 32P from [gamma-32P] ATP into polyphosphoinositides and phosphatidic acid in subcellular particles of guinea pig brain. PMID- 4294504 TI - Studies on cytochrome a. 18. The state of existence of copper in cytochrome a and its contribution to the oxidase activity. PMID- 4294505 TI - Uroterpenol beta-D-glucuronide. PMID- 4294506 TI - Clinical aspect of trophoblastic growth and postoperative follow-up of hydatidiform mole using basal body temperature measurement. PMID- 4294507 TI - Factors influencing the measurement of conduction velocity in the human peripheral nerve. PMID- 4294508 TI - Influence of angiotensin on the effects of tyramine upon the contractile-force of isolated rabbit atria. PMID- 4294509 TI - Drug effects on cardiac myosin adenosine triphosphatase activity. PMID- 4294510 TI - Calcification of superficial nerves in leprosy. PMID- 4294511 TI - Nerve abscess in lepromatous leprosy--report of a patient. PMID- 4294512 TI - Herpesvirus infections of the human central nervous system. PMID- 4294513 TI - Encephalitis caused by herpes-simplex virus. PMID- 4294514 TI - [Neuroleptic drugs]. PMID- 4294515 TI - Stretching and yawning movements after intracerebral injection of ACTH. PMID- 4294516 TI - Modifications by catecholamines of pressor responses to angiotensin in pithed rats. PMID- 4294517 TI - A thecoma of ovary causing precocious puberty in a baby aged 6 months. PMID- 4294518 TI - [A case of bilateral reticulum cell sarcoma of the testis treated by intralymphatic irradiation with I131 ethiodol after bilateral orchiectomy]. PMID- 4294519 TI - Skeletal development in gonadal dysgenesis, female in phenotype. PMID- 4294520 TI - The role of radiotherapy in the management of malignant tumors of the salivary glands. PMID- 4294521 TI - Renin-angiotensin system in microembolic renal hypertension. PMID- 4294522 TI - [Antiviral activity of guanidine and D-penicillamine. I. Inhibition by guanidine and D-penicillamine of RNA synthesis of poliovirus]. PMID- 4294523 TI - [Antiviral activity of guanidine and D-penicillamine. II. Comparative study of antagonists of guanidine and D-penicillamine]. PMID- 4294524 TI - A super parasite. PMID- 4294525 TI - Tobacco carcinogenesis. IX. Effect of cigarette smoke on respiratory tract of mice after passive inhalation. PMID- 4294526 TI - An electron microscopic study of pulmonary tumor emboli from transplantable Morris hepatoma 5123. PMID- 4294527 TI - A search for urinary 4',10-dimethyl-1,2-benzanthracene and other hydrocarbons. PMID- 4294528 TI - Association of embryonic antigens with experimentally induced hepatic lesions in the rat. PMID- 4294529 TI - Some properties of beta-glucuronidase activity in normal rat liver and in several transplantable rat hepatomas. PMID- 4294530 TI - Establishment of transplantable hepatomas induced by 3'-methyl-4 dimethylaminoazobenzene with special reference to the histologic features of the transplants of early passages. PMID- 4294531 TI - Effect of heterologous antilymphoid-cell serum on tumor isografts and viral leukemogenesis. PMID- 4294532 TI - Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine. PMID- 4294533 TI - Cytochemical studies on the mouse mammary tumor virus. PMID- 4294534 TI - Comparative studies of the nucleoli of Morris hepatomas, embryonic liver, and aflatoxin B1-treated liver of rats. PMID- 4294535 TI - Screening data from the cancer chemotherapy National Service Center Screening Laboratories. XLV. PMID- 4294536 TI - Incorporation of 14-C-labeled acetate into lipid by isolated foam cells and by atherosclerotic arterial intima. PMID- 4294537 TI - Enhancement of peripheral alpha-receptor stimulation by blockade of "silent" beta receptors. PMID- 4294538 TI - Sequential solvent extraction of urinary corticosteroids and its clinical application. PMID- 4294539 TI - [Visual light and adrenal cortex function]. PMID- 4294540 TI - [On the etiology of an unknown human infection originating from monkeys]. PMID- 4294541 TI - Embryogenesis in Hymenolepis diminuta. IV. Distribution of succinic dehydrogenase, reduced form of nicotinamide-adenine dinucleotide oxido-reductase, and cytochrome oxidase. PMID- 4294542 TI - Lipids from Entamoeba histolytica. PMID- 4294543 TI - Carcinomatous neuromyopathy. The nonmetastatic neurological complications of cancer. PMID- 4294549 TI - Effect of melatonin and 5-hydroxytryptamine on aldosterone and corticosterone production by adrenal glands of normal and hypophysectomized rats. PMID- 4294550 TI - Gel filtration of oestrogen conjugates in bovine urine. PMID- 4294551 TI - A rapid method for extracting corticotrophin from plasma. PMID- 4294552 TI - Model reactions for the biosynthesis of thyroxine. XI. The nature of a free radical formed in the autoxidation of 4-hydroxy-3,5-diiodophenylpyruvic acid. PMID- 4294553 TI - Anogenital cutaneous lesions. PMID- 4294554 TI - [Studies on induced skin-sensitizing antibodies]. PMID- 4294555 TI - [On the histopathology and histogenesis of various salivary gland tumors]. PMID- 4294556 TI - [The methods of selective angiographic and subtraction exploration applied to the diagnosis of nasopharyngeal angiofibroma. Therapeutic considerations]. PMID- 4294557 TI - [Morbidity of pulmonary silicosis in the 3 largest factories of fireproof materials in the province of Cracow]. PMID- 4294558 TI - Viral neoplastic transformation of hamster prostate tissue in vitro. AB - Cultures of hamster prostatic tissues infected with simian virus 40 undergo transformation in vitro, and the transformed cells produce malignant tumors when injected into homologous hosts. Tartrate-inhibited acid phosphastase is found in the cultures of transformed cells and in the tumors they produce. Tartrate inhibited acid phosphatase activity is elevated in the serum of tumor-bearing animals. PMID- 4294559 TI - [Preliminary observations of the treatment of myasthenia by azathioprine]. PMID- 4294560 TI - Adrenal cortex in marasmic children. PMID- 4294561 TI - Lymphocyte and granulocyte enzyme activity in patients with Down's syndrome. PMID- 4294562 TI - [Relationship between the multiplicity of infection by polyoma virus and induction of the nuclear tumor antigen]. PMID- 4294563 TI - [Comparison with chromatography on DEAE-Sephadex of hemagglutinins of Japanese B encephalitis virus (Nakayama strain) and of a neighboring strain isolated in Vietnam]. PMID- 4294564 TI - [Medification of the hypertensive effects of catecholamines and of Val-5 angiotensin II in the rat, by the use of several estrogens]. PMID- 4294565 TI - Relationship of histologic features to behavior of cystosarcoma phyllodes. Analysis of ninety-four cases. PMID- 4294566 TI - Herpes-type virus infection in adult with hematologic disorder. Electron microscopic observations of virus and case report. PMID- 4294567 TI - Cancer mortality among patients in New York mental hospitals. PMID- 4294568 TI - Wilms' tumour-a review of 45 consecutive cases. PMID- 4294569 TI - [Results of the determination of plasma renin]. PMID- 4294570 TI - Metabolism of vitamin D3-3H in vitamin D-resistant rickets and familial hypophosphatemia. AB - The fate of an intravenous dose of tritiated vitamin D(3) was studied in seven normal subjects, four children with vitamin D-resistant rickets, and four adults with a familial history of vitamin D-resistant rickets and persistent hypophosphatemia. An abnormal metabolism of vitamin D in vitamin D-resistant rickets was defined and characterized by a decrease in the plasma fractional turnover rate, a marked increase in plasma water-soluble metabolites, and a relative decrease in the conversion of vitamin D to a polar, biologically active metabolite. Alterations in vitamin D metabolism in the adults with persistent hypophosphatemia were similar but less severe than those of affected children with vitamin D-resistant rickets. It is tentatively concluded that the abnormalities in vitamin D metabolism documented in patients with vitamin D resistant rickets and familial hypophosphatemia may account for the observed osseous and biochemical changes. PMID- 4294571 TI - A study of mechanisms by which adrenocorticotropic hormone maintains adrenal steroidogenic responsiveness. AB - Following hypophysectomy in the rat, there was a progressive decline in the rate of adrenal protein synthesis in vivo during the ensuing 24-48 hr, and an accompanying decrease in the acute corticosterone secretory response to an intravenous injection of ACTH. There was a similar decrease in the in vitro conversion of Delta(5)-pregnenolone, progesterone, and deoxycorticosterone to corticosterone. These in vivo and in vitro effects of hypophysectomy could be reversed by the administration of depot ACTH for an additional 7 hr period. However, if cycloheximide, an inhibitor of protein synthesis, was administered concomitantly with the depot ACTH, then the restorative actions of ACTH on the steroid biosynthetic pathway were prevented. These experiments suggest that ACTH maintains not only the general structure of the adrenal cortex, but also the level of the steroid biosynthetic mechanism, through its effects on adrenal protein synthesis. PMID- 4294572 TI - The role of sodium-potassium-activated adenosine triphosphatase in the reabsorption of sodium by the kidney. AB - In order to evaluate the possible role of sodium- and potassium-activated adenosine triphosphatase in the active transport of sodium by the renal tubules, we examined the effect of large changes in the tubular reabsorptive load of sodium on the Na-K-ATPase activity of rat kidney homogenates. Glomerular filtration and tubular reabsorption of sodium per gram of kidney tissue increased progressively after contralateral uninephrectomy. This was paralleled by an increase in Na-K-ATPase per milligram of protein in a microsomal fraction of kidney cortex. The importance of this change is underlined by the absence of simultaneous increases in other microsomal enzymes such as glucose-6-phosphatase and Mg(++)-dependent ATPase, or in succinic dehydrogenase or glutaminase. Similar increases in Na-K-ATPase were observed when the net tubular reabsorption of sodium was increased by feeding the animals a high-protein diet or after injection of methylprednisolone. On the other hand, Na-K-ATPase was lowered when tubular transport of sodium was reduced by bilateral adrenalectomy. The results of these experiments show that renal Na-K-ATPase changes in an adaptive way when renal reabsorption of sodium is chronically increased or diminished and support the hypothesis that this enzyme system is involved in the process by which sodium is actively transported across the renal tubule. PMID- 4294573 TI - A study on the virus aetiology of mild respiratory infections in the primary school child. PMID- 4294574 TI - [Study on chemotherapy of virus infections of the respiratory organs]. PMID- 4294575 TI - Hypophosphatasia: clinical and metabolic studies. PMID- 4294576 TI - Familial holoprosencephaly with endocrine dysgenesis. PMID- 4294577 TI - [Clinical studies on the biosynthesis, secretion and metabolism of cortisol. I. The urinary excretions of tetrahydro-11-desoxycortisol, tetrahydrocortisone and tetrahydrocortisol in normal young and elderly subjects and their responses to the methopyrapone test and to the zinc-corticotropin test in both groups]. PMID- 4294578 TI - [Isolation of human cytomegalovirus and sero-epidemiological study of its infection]. PMID- 4294579 TI - [Criteria for identification of C1. welchu. 3. Re-evaluation of gelatin nonliquifying and salicin-fermenting strains]. PMID- 4294580 TI - [Iodoventriculography]. PMID- 4294581 TI - [Development and value of complementary examinations in the diagnosis of intracranial tumors. Summary]. PMID- 4294582 TI - [Echoencephalography in the detection of intracranial neoformations]. PMID- 4294583 TI - [Gamma-encephalography]. PMID- 4294584 TI - [Carotid angiography]. PMID- 4294585 TI - Cartilage and cartilage grafts: the basic properties of the tissue and the components responsible for them. PMID- 4294586 TI - Intramedullary tumours of the spinal cord. PMID- 4294587 TI - Experiments with 8 nerve section and the cochleo-cochlear mechanisms. PMID- 4294588 TI - Histological and histochemical studies on cholesteatoma epidermis. PMID- 4294589 TI - Ultrastructure of the glomus jugulare tumor. PMID- 4294590 TI - Head colds and viral cochleitis. PMID- 4294591 TI - [Acid-catalized rearrangement of alpha-diols in the 4,4-dimethyl steroid series. II. 4,4-Dimethyl(5 alpha) or (5 beta)androstan-6-one]. PMID- 4294592 TI - [Further follow-up on the survival after biological resection]. PMID- 4294593 TI - Membrane lipid changes during formation of a functional electron transport system in Staphylococcus aureus. AB - Addition of oxygen to a culture of anaerobically growing Staphylococcus aureus results in the formation of a membrane-bound, functional electron transport system. With the shift to aerobic growth, there is at least a 15-fold increase in cytochrome a and at least a 55-fold increase in cytochrome oxidase o. At the completion of the shift to aerobic growth, the cytochrome levels equal those found in bacteria grown with aeration throughout the entire growth cycle. Cytochromes b(1) and o are formed first. Their synthesis slows when cytochrome a becomes detectable. Concentrations of cytochromes b(1) and sometimes cytochrome a increase late in the adaptive period. Concomitant with this is a decrease in the oxygen tension at which the rate of oxygen utilization becomes dependent on the oxygen concentration. During the shift to aerobic growth, the protoheme content increases ninefold, and all the protoheme can be accounted for in enzymatically reducible cytochrome b(1) and cytochrome oxidase o. Protoheme, but not a functional cytochrome system, is synthesized by anaerobically growing S. aureus. Heme a appears only after a period of aerobic growth. During the shift to aerobic growth, there is a 1.6-fold increase in the vitamin K(2) content, with an alteration in the ratios of the 35 and 45 carbon side chain isoprenologues. A twofold increase in phosphatidyl glycerol and a 1.6-fold increase in cardiolipin occur with the shift to aerobic growth. Lysyl-phosphtidyl glycerol remains essentially constant in this period. Concentrations of mono- and diglucosyl diglycerides increase coordinately 1.3-fold during the shift to aerobic growth at a 2.5 to 1 m ratio. PMID- 4294594 TI - O-methylthreonine inhibition of growth and of threonine deaminase in Escherichia coli. AB - O-methylthreonine (OMT), an isosteric analogue of isoleucine, markedly inhibited growth of Escherichia coli 15. This inhibition was overcome most effectively by addition of isoleucine, valine, or leucine to the medium and less effectively by addition of threonine. The dipeptide, valylleucine, also relieved the OMT-induced inhibition but only after a lag period, suggesting that valine and leucine, liberated by dipeptidase action, compete with OMT for entry into the cell. OMT was activated and transferred to transfer ribonucleic acid (RNA) by isoleucyl-RNA synthetase in vitro. The rate of OMT incorporation into protein of intact cells was comparable to that of isoleucine. In contrast to isoleucine, very high concentrations of OMT were required to inhibit threonine deaminase, and the inhibition was strictly competitive with threonine. In addition, OMT inhibited a threonine deaminase preparation desensitized to isoleucine inhibition. PMID- 4294596 TI - Numerical data concerning the sensitivity of anaerobic bacteria to oxygen. AB - Upon comparison of results obtained from growing eight different species of anaerobic bacteria in deep agar under two and three atm of pure oxygen with results of growing them in air under atomospheric pressure, it appears possible that the old terms of "microaerophobic," "very strict anaerobe," and "microaerophilic" can be replaced by precise values corresponding to the size of the inhibition zone produced by oxygen under various pressures when the bacteria are grown in a solid medium. The simultaneous effect of the dilution of the inoculum and the pressure of oxygen used was determined with the help of an electronic computer according to the standard multiple regression method. Two indices have been worked out which express the sensitivity of the species at different oxygen pressures when varying numbers of anaerobic bacteria are used: X sp, which is the size in millimeters of the inhibition zone when 1:10 dilutions of the culture are grown under pure oxygen at atmospheric pressure (lp=0), and B sp, which is the result of multiplying by 1.43 the difference in size of inhibition zone when 1:10 dilutions of the culture are grown under atmospheric air (lp = -0.7) and under pure oxygen at 1 atm absolute. PMID- 4294595 TI - Release of surface enzymes in Enterobacteriaceae by osmotic shock. AB - The process of osmotic shock, which has been used to release degradative enzymes from Escherichia coli, can be applied successfully to other members of the Enterobacteriaceae. Cyclic phosphodiesterase (3'-nucleotidase), 5'-nucleotidase (diphosphate sugar hydrolase), acid hexose phosphatase, and acid phenyl phosphatase are released from Shigella, Enterobacter, Citrobacter, and Serratia strains. Some strains of Salmonella also release these enzymes. Members of Proteus and Providencia groups fail to release enzymes when subjected to osmotic shock and do not show a lag in regrowth, although they do release their acid soluble nucleotide pools. In contrast to E. coli, release of enzymes from other members of the Enterobacteriaceae studied is affected by growth conditions and strain of organism. None of the organisms was as stable to osmotic shock in exponential phase of growth as was E. coli. Exponential-phase cells of Shigella, Enterobacter, and Citrobacter could be shocked only with 0.5 mm MgCl(2) to prevent irreparable damage to the cells. These observations suggest that this group of degradative enzymes is probably loosely bound to the cytoplasmic membrane through the mediation of divalent cations. PMID- 4294597 TI - Angiotensin-aldosterone interrelationship in liver cirrhosis. PMID- 4294598 TI - Light and electron microscopy of adrenocorticotrophin-induced renal glomerular disease in mice. PMID- 4294599 TI - The introduction of hydrocyanic acid into medicine. A study in the history of clinical pharmacology. PMID- 4294600 TI - [Sociotherapy and rehabilitation of schizophrenic patients]. PMID- 4294601 TI - [Frey's syndrome and the middle ear]. PMID- 4294602 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 3-1968. PMID- 4294603 TI - [The nervous manifestations of chronic uremia. Apropos of certain clinical, E.E.G. and neuropathologic aspects]. PMID- 4294604 TI - [Angiotensin and its related substances]. PMID- 4294605 TI - Irradiation of dihydropyrimidines. PMID- 4294606 TI - Rapid labeling of RNA in Saccharomyces cerevisiae during gamma irradiation correlated with catalase formation. PMID- 4294607 TI - Treatment of aplastic anemia in children. PMID- 4294608 TI - [Various aspects of the action of angiotensin II in essential arterial hypertension]. PMID- 4294609 TI - Pharmacologic and endocrine aspects of carcinoid syndrome. PMID- 4294610 TI - [The treatment of anovular uterine hemorrhage with ACTH and desoxycorticosterone]. PMID- 4294611 TI - Sarcoma of the breast. PMID- 4294612 TI - Reticulum cell sarcoma: demonstration of chromosomal changes analogous to those in SV40-transformed cells. PMID- 4294613 TI - Cancer hazard from mineral oil used in the processing of jute. PMID- 4294614 TI - Development of adrenal cortical carcinoma in C3H mice following castration and the administration of 7,12-dimethylbenz(a)anthracene. PMID- 4294615 TI - Effect of age, sex, and hormonal state on tritiated thymidine uptake by rat pituitary. PMID- 4294616 TI - Demonstration of tumour-specific humoral antibody against aminoazo dye-induced rat hepatomata. PMID- 4294617 TI - An unusual breast tumour in an adolescent girl. PMID- 4294618 TI - Viruses of the alimentary tract of chimpanzees. PMID- 4294619 TI - A structural analysis of hepatomegaly induced by a hormone-secreting tumor. PMID- 4294621 TI - A study on natural infection of simian virus 40 (SV40) in Taiwan monkeys (Macaca cyclopis). PMID- 4294620 TI - Steroid conjugates. 3. The synthesis of sulfoglucuronide derivative of estriol. PMID- 4294622 TI - Biochemistry of the development of duck embryo. 1. Some enzymes of carbohydrate metabolism in the developing liver. PMID- 4294623 TI - Disseminated herpes simplex virus infection. PMID- 4294624 TI - Intrathoracic chemodectoma. PMID- 4294625 TI - Macroradiography in 4 times magnification applied to cerebral angiography. PMID- 4294626 TI - Conversion of angiotensin I to angiotensin II. PMID- 4294627 TI - Virus-like particles in blood lymphocytes in acute Marek's disease. PMID- 4294629 TI - Electron spin resonance investigation of conformation changes in serum albumin with the help of iminoxyl paramagnetic label. PMID- 4294628 TI - Lack of resistance of adult mice to erythrocyte-borne Bittner virus. PMID- 4294630 TI - Transmission in invertebrate and vertebrate ganglia. PMID- 4294631 TI - [Primary cancer of the liver in cirrhosis. Increase in the incidence and observation in known and follow-up cirrhotic patients]. PMID- 4294632 TI - [Hormonal control of melanin pigmentation]. PMID- 4294633 TI - Definitive diagnosis of insulin-secreting tumors of the pancreas. PMID- 4294634 TI - Further studies on the production of interferon by human leukocyte in vitro. PMID- 4294635 TI - [Action of diazoxide in a severe case of hyperinsulinism due to an operated Langerhansian carcinoma complicated by hepatic metastases]. PMID- 4294636 TI - [Etiological considerations on human and animal enterotoxemias of W. perfringens type A]. PMID- 4294637 TI - [Action of nickel on the liberation of the transmitter at the neuromuscular junction]. PMID- 4294638 TI - [Preliminary findings, in the dog, on the histochemical state of the preserved and perfused liver]. PMID- 4294639 TI - [Study of the action of silicic compounds on experimental atheroma]. PMID- 4294640 TI - Mitochondrial functions of polymelanosomes. PMID- 4294641 TI - The oxidase systems of Moniezia expansa (Cestoda). PMID- 4294642 TI - Effect of hypophysectomy on the fatty acids and lipid classes of rat testes. PMID- 4294643 TI - Effect of insulin on the synthesis of glycogen in cerebral cortical slices of alloxan diabetic rats. PMID- 4294644 TI - Pharmacologic effects of angiotensin-II-amide on aldosterone and corticosterone secretion by the intact anesthetized rat. PMID- 4294645 TI - [Glass microelectrodes with metallic conductor for extracellular recording of potentials]. PMID- 4294646 TI - Islet cell adenoma of pancreas. A case report and brief review of literature. PMID- 4294647 TI - The effect of long-term corticotrophin treatment on the corticosteroid-binding capacity of transcortin. PMID- 4294648 TI - The influence of hypophysectomy, corticotrophin and cortisol on the adrenal medulla of the rat. PMID- 4294649 TI - Induction of interference and interferon synthesis by non-replicating molluscum contagiosum virus. PMID- 4294650 TI - Photodynamically inactivated vaccines prepared by growing viruses in cells containing neutral red. PMID- 4294651 TI - Prevention of SV40 virus oncogenesis in hamsters. II. The effect of thymectomy on induction of tumor resistance by SV40-transformed human cells. PMID- 4294652 TI - Microslide acrylamide gel electrophoresis technique for tissue lactic dehydrogenase. PMID- 4294653 TI - An immunofluorescent method for Yaba virus assay. PMID- 4294654 TI - Changes in Simian Virus 40 susceptibility and chromosome numbers during long-term cultivation of BS-C-1 cells. PMID- 4294655 TI - Regulation of cytochrome oxidase in human cells in culture. PMID- 4294656 TI - Influence of the injection of "Triton WR-1339" on lysosomes of a rat transplantable hepatoma. PMID- 4294657 TI - [Adenosarcoma of both kidneys in an infant]. PMID- 4294658 TI - [An infection by the virus of smallpox vaccine]. PMID- 4294659 TI - [Erythrodermia postoperativa: report of a case]. PMID- 4294660 TI - [Discharge of neutral 17-ketosteroids in patients with uterine myoma]. PMID- 4294661 TI - The effects of ionizing radiation on nucleic acids of bacteriophages and bacterial cells. PMID- 4294662 TI - Liver enlargement and hepatoxicity: an investigation into the effects of several agents on rat liver enzyme activities. PMID- 4294663 TI - Effect of angiotensin on uptake and release of norepinephrine by brain. PMID- 4294664 TI - Subcellular localization of ethylenediaminetetraacetate in the proximal tubular cell of the rat kidney. PMID- 4294665 TI - Stress and the maintenance of nicotinamide-induced hepatic nicotinamide adenine dinucleotide elevation by chlorpromazine. PMID- 4294666 TI - The control of glycolysis in early embryogenesis. PMID- 4294667 TI - Major metabolic pathways of glucose in normal human lymphocytes and the effect of cortisol. PMID- 4294668 TI - Evidence of reduction of fumarate to succinate in perfused rat liver under conditions of reduced O2 tension. PMID- 4294669 TI - Nitroxide mixed carboxylic-carbonic acid anhydrides. A new class of versatile spin labels. PMID- 4294670 TI - Titration of tuberculin, nucleic acids and viruses by haemaggregation inhibition using a "pattern" test. PMID- 4294671 TI - Aldosterone production and juxtaglomerular granules. PMID- 4294672 TI - Human embryo kidney fibroblasts for the isolation and growth of rhinoviruses. PMID- 4294673 TI - A study of the production, source and action of interferon appearing in mice after the intravenous injection of influenza virus. PMID- 4294674 TI - Endemic goitre in eastern New Guinea, with special reference to the use of iodized oil in prophylaxis and treatment. PMID- 4294676 TI - Breast carcinoma. A histological and prognostic study of 650 followed-up cases. PMID- 4294675 TI - Auscultatory sign in primary carcinoma of the liver. PMID- 4294677 TI - [Relationship between plasma sodium, hypertension and plasma and erythrocyte sodium concentration]. PMID- 4294678 TI - [On the practical value of angiotensin test according to Kaplan and Silah in the diagnosis of renovascular hypertension]. PMID- 4294679 TI - [Nature and therapy of "drug withdrawal symptoms" following longterm corticosteroid therapy?]. PMID- 4294680 TI - Ultrastructure of methylcholanthrene-induced fibrosarcomas in the Swiss albino mouse. PMID- 4294681 TI - A difference in mechanism by which leucine and other amino acids induce insulin release. PMID- 4294682 TI - Variation in the oncogenic potential of human adenoviruses carrying a defective SV40 genome (PARA). AB - The acquisition of the defective SV40 genome by a variety of human adenovirus serotypes by the process of transcapsidation has resulted in the addition of oncogenic potential for newborn hamsters to the previously nononcogenic adenovirus types 1, 2, 5, and 6. These serotypes have previously been grouped together by the high GC content of their DNA. Transcapsidation of the SV40 genome to weakly oncogenic adenovirus types 3, 14, 16, and 21 has failed to increase their oncogenic potential although the parent adenovirus type 7 carrying PARA is highly oncogenic. These serotypes belong to the group possessing a DNA of intermediate GC content. All the PARA-adenovirus populations, even those that were nononcogenic, were able to induce SV40 transplantation immunity and therefore carry the SV40 transplantation marker as well as the marker for synthesis of SV40 tumor or T antigen. PMID- 4294684 TI - Radiologic seminar LXVII: bronchial adenoma. PMID- 4294683 TI - Adeno-associated satellite virus interference with the replication of its helper adenovirus. AB - Adeno-associated satellite virus type 4 interferes with the replication of its helper adenovirus. No interferon-like soluble substance could be detected in satellite-infected cultures and other DNA- and RNA-containing viruses were not inhibited by coinfection with satellite virus under conditions which reduced adenovirus yields by more than 90% in monkey cells. Altering the concentration of adenovirus in the presence of constant amounts of satellite resulted in a constant degree of interference over a wide range of adenovirus inocula and suggested that adenovirus concentration was not a significant factor in the observed interference. The interference with adenovirus replication was abolished by pretreating satellite preparations with specific antiserum, ultraviolet light or heating at 80 degrees C for 30 min. This suggested that infectious satellite virus mediated the interference. Satellite virus concentration was found to be a determinant of interference and studies indicated that the amount of interference with adenovirus was directly proportional to the concentration of satellite virus. 8 hr after adenovirus infection, the replication of adenovirus was no longer sensitive to satellite interference. This was true even though the satellite virus was enhanced as effectively as if the cells were infected simultaneously with both viruses. Interference with adenovirus infectivity was accompanied by reduced yields of complement-fixing antigen and of virus particles which suggested that satellite virus interfered with the formation and not the function of adenovirus products. When cells were infected either with adenovirus alone or with adenovirus plus satellite, the same proportion of cells plated as adenovirus infectious centers. However, the number of plaque-forming units of adenovirus formed per cell in the satellite-infected cultures was reduced by approximately 90%, the same magnitude of reduction noted in whole cultures coinfected with satellite and adenovirus. This suggested that all cells infected with the two viruses were producing a reduced quantity of adenovirus. PMID- 4294685 TI - [The evaluation of non-sepcific phosphomonoesterases in the stria vascularis and spiral ligament of the normal guinea pig]. PMID- 4294686 TI - Cylindromas of the head and neck. PMID- 4294687 TI - [2 Cases of granular cell myoblastoma of the breast]. PMID- 4294688 TI - Studies on rous sarcoma virus in mice. II. Clonal analysis of cell populations of the SR-RSV-induced mouse ascites sarcoma (SR-C3H/HE ascites). PMID- 4294689 TI - Vincristine neurotoxicity in rodents. PMID- 4294690 TI - Propagation and cytopathic effects of Japanese encephalitis and related viruses in mammalian cerebellar tissue cultures. PMID- 4294691 TI - Studies on glycogen contents of cerebral cortex in hyperthermia, hypothermia and administration of several drugs. PMID- 4294692 TI - Electrophoretic mobility and biological behaviors of rat ascites hepatoma cells. PMID- 4294693 TI - Respiratory distress and convulsions in newborn. PMID- 4294694 TI - [Role of adenoviruses in the etiology of respiratory tract diseases]. PMID- 4294695 TI - [Treatment of acute inflammations of the upper respiratory tract in early infancy by the method of hydroionization]. PMID- 4294696 TI - [A case of arrhenoblastoma of the ovary]. PMID- 4294697 TI - A fatal case of dengue hemorrhagic fever in an American child. PMID- 4294698 TI - Wilms' tumor and congenital hemihypertrophy: report of five new cases and review of literature. PMID- 4294699 TI - [Bronchiolo-alveolar epithelioma of the lung. Apropos of a unicentric case]. PMID- 4294700 TI - [Lymphography by Popiodol]. PMID- 4294701 TI - [Diagnosis and therapy of renal artery stenosis]. PMID- 4294702 TI - [On the question of corticosteroid therapy of acute postinfectious polyradiculoneuropathy (so called Guillain-Barre syndrome)]. PMID- 4294703 TI - Initial, presumptive therapy for serious acute gram-negative rod infections: preliminary report of a controlled clinical trial. PMID- 4294704 TI - Immunogenicity of bovine rhinotracheitis--virus diarrhea vaccine in cattle inoculated simultaneously with concentrated homologous antiserum. PMID- 4294705 TI - [Humoral factors of nervous excitation in rheumatoid arthritis in children]. PMID- 4294706 TI - [The use of corticosteroids in various phases of rheumatism in children]. PMID- 4294707 TI - [Changes in the main digestive glands in rheumatism during treatment with ACTH and prednisolone]. PMID- 4294708 TI - Blood glucose level in mice. 3. On the nature of corticotrophin-induced hypoglycaemia. PMID- 4294709 TI - Specific antigen of tumor cell transformed by DNA extracted from SV-40 virus. PMID- 4294710 TI - Disseminated herpes simplex virus infection. Its pathogenesis based on virological and pathological studies in 33 cases. PMID- 4294711 TI - Effect of lactation and perchlorate on thiocyanate metabolism. PMID- 4294712 TI - Effect of beta irradiation on ganglionic bioelectric activity. PMID- 4294713 TI - Metabolic effects of angiotensin. PMID- 4294714 TI - Autoregulation of renal blood flow in the presence of angiotensin infusion. PMID- 4294715 TI - Regional differences in vascular tachyphylaxis to angiotensin in the cat. PMID- 4294716 TI - Association of zoster and malignant disorders in children. PMID- 4294717 TI - Two complications of trigeminal injury occurring in one patient. PMID- 4294718 TI - [Herpes simplex virus type 1 and 2 in various disease enities]. PMID- 4294719 TI - Tetrodotoxin's highly selective blockage of an ionic channel. PMID- 4294720 TI - [The effect of long term exposure to quartz on permanent cell cultures]. PMID- 4294721 TI - [Infrared spectroscopic studies of lung dust]. PMID- 4294722 TI - Studies on the development of a radioimmunoassay for angiotensin II. PMID- 4294723 TI - A fundamental defect of adrenocortical control in Cushing's disease. PMID- 4294724 TI - Steroid secretion by the adrenal gland of foetal and neonatal sheep. PMID- 4294725 TI - Double isotope assay of aldosterone, corticosterone and cortisol in human peripheral plasma. PMID- 4294726 TI - Ultrastructural studies of experimental vesiculation. II. Collagenase. PMID- 4294727 TI - [Sensitivity of HeLa cells continously infected with HVJ to other types of viruses]. PMID- 4294728 TI - [Study on pleomorphism of hemagglutinating viruses of Japan]. PMID- 4294729 TI - Studies of ultrastructural changes in liver cells. I. Electron microscopic observations on human and rat liver in hyperthyroidism. PMID- 4294730 TI - A simple and sensitive procedure for the microdtermination of nitrogen in biological materials. PMID- 4294731 TI - [Clinical picture of endocrine pancreatic tumors]. PMID- 4294732 TI - [XXXIV. Multiple endocrine hyperplasia and adenoma syndrome (MEHA syndrome) with Zollinger-Ellison syndrome]. PMID- 4294733 TI - Thin-layer chromatography. PMID- 4294734 TI - Effect of humming on vision. PMID- 4294735 TI - Site of attachment of retinal in rhodopsin. PMID- 4294736 TI - Amino-acid sequence of glyceraldehyde 3-phosphate dehydrogenase from lobster muscle. PMID- 4294737 TI - Determination of free radicals in gamma irradiated proteins. PMID- 4294738 TI - Inhibition of multiplication of foot and mouth disease virus in adult mice pretreated with Freund's complete adjuvant. PMID- 4294739 TI - Myasthenia gravis treated with ACTH. PMID- 4294740 TI - Interferon: production by chick erythrocytes activated by cell fusion. AB - In the presence of Sendai virus inactivated with ultraviolet light, nucleated chick erythrocytes can be fused with several types of human cells to form heterokaryons. Although chick erythrocytes alone cannot be stimulated by Sendai virus to produce interferon, fusion with a human cell (AH-1) which itself may produce human interferon results in heterokaryons in which the erythrocyte genome is activated and chick interferon is produced. When nucleated chick erythrocytes are fused with another type of human cell (HeLa clone S-3) which does not produce human interferon when stimulated, no chick interferon is detectable, despite morphologic changes suggestive of activation of the erythrocyte nuclei. PMID- 4294741 TI - [Ruptured hepatoma treated by emergency right hepatectomy]. PMID- 4294742 TI - Effect of high-power ruby laser irradiation on peripheral nerve. PMID- 4294743 TI - [Use of thin layer chromatography on silica for the separation and estimation of 17-oxosteroids of the androstane series]. PMID- 4294744 TI - The effect of 5-bromo-2-deoxyuridine on the multiplication of equine herpes 3 virus in rabbit kidney cells. PMID- 4294745 TI - [Complementary study of the "developmental thermosensitivity" factor of poliomyelitis virus using the method of Carp and Koprowski]. PMID- 4294746 TI - Kinetic studies of temperature changes and oxygen uptake in a differential calorimeter: the heat of oxidation of NADH and succinate. PMID- 4294747 TI - Induction of the division cycle in resting stage human fibroblasts after RSV infection. PMID- 4294748 TI - Mossbauer effect in peroxidase. PMID- 4294749 TI - Persistance of the effects of regulatory reagents on conformation of catalytically inactive glutamate dehydrogenase. PMID- 4294750 TI - [Interrealtions between catecholamines and angiotensin]. PMID- 4294751 TI - [Demonstration of the milk factor in the PS strain of mice by ultracentrifugation on Ficoll gradients. Association of the viral particles with mycoplasma]. PMID- 4294752 TI - Some aspects of the hydrolysis of phosphomonoesters by homogenates of growing and regressing mesonephroi in chick embryos. PMID- 4294753 TI - Mast cells in nerves affected with fowl paralysis (Marek's disease). PMID- 4294754 TI - [Relations between phagocytizing, virus-infecting hen myeloblasts in vitro and the "gray bodies"]. PMID- 4294755 TI - Method for obtaining several microcultures in the same petri dish. PMID- 4294756 TI - [Functional evaluation of the pituitary gland with the metyrapone test and determination of ACTH in the blood]. PMID- 4294758 TI - [An electron microscopic study on cells infected with the Herpes virus. (2nd report)]. PMID- 4294757 TI - [Intercurrent relationships between nyctohemeral rhythm of elimination of gonadotropins and adrenal cortex steroids]. PMID- 4294759 TI - The value of extended incubation and subcultures in the isolation of Entamoeba histolytica from stool specimens. PMID- 4294760 TI - [On paramagnetic properties of manganese in plant ashes]. PMID- 4294761 TI - [Angiotensin resistance test in arterial hypertension of renal origin. Limitations and indications]. PMID- 4294762 TI - [On the significance of post-remissive exhaustion-syndrome for the rehabilitation of schizophrenics]. PMID- 4294763 TI - [On the surgical treatment of the median tarsal tunnel syndrome]. PMID- 4294764 TI - [On the differences in urea resistance of lactate dehydrogenase from the rat's liver and thymus cells]. PMID- 4294765 TI - [Study in the unique cycle of wild and modified foot-and-mouth disease virus]. PMID- 4294766 TI - Silica excretion in cattle fed a ration predisposing to silica urolithiasis: total excretion and diurnal variations. PMID- 4294767 TI - Experimental infection of calves with myxovirus parainfluenza-3 and Pasteurella haemolytica. PMID- 4294768 TI - Application of stresses to foot-and-mouth disease virus. PMID- 4294769 TI - Application of the agar gel technique in the diagnosis of infectious bovine rhinotracheitis. PMID- 4294770 TI - Adrenergic neurone blocking activity of some new guanidine derivatives. PMID- 4294771 TI - Influence of new guanidine derivatives on ganglionic and neuromuscular transmission. PMID- 4294772 TI - Some effects of morphine on pituitary-adrenocortical function in the rat. PMID- 4294773 TI - Comparison of the effects of disulfiram and dimercaptopropanol arsenite on mitochondrial structure and function. PMID- 4294774 TI - A phosphodiesterase from the carrot. PMID- 4294775 TI - The properties of dicyclohexylcarbodiimide as an inhibitor of oxidative phosphorylation. PMID- 4294776 TI - A new assay for adenosine 3',5'-cyclic monophosphate in tissue. PMID- 4294777 TI - [Contribution to the classification of epithelial skin tumors]. PMID- 4294778 TI - [Examination of the hypophyseo-adrenal function during acute hepatitis]. PMID- 4294779 TI - Fatty acid components of lipid fractions of Yoshida sarcoma and rat ascites hepatomas. PMID- 4294780 TI - Aftercare for former day hospital patients. PMID- 4294781 TI - Serological reactions in sheep-pox. II. Agar-gel diffusion test. PMID- 4294782 TI - Effects of hormones on the renal response to unilateral nephrectomy in hypophysectomized rats. PMID- 4294783 TI - [Rapidly and slowly reducible heme-a complexes]. PMID- 4294784 TI - [Study on ACTH allergy]. PMID- 4294786 TI - An unusual course of experimental mouse virus leukaemia. PMID- 4294785 TI - [Microgyria and aplasia of one cerebellar hemisphere in generalized cytomegaly]. PMID- 4294787 TI - Changes in the cultures of chicken bone marrow cells infected with the virus of chicken myelocytomatosis (strains Mc-29 and Mc-31). PMID- 4294788 TI - Susceptibility of turkey-poults to avian leukosis strains Mc-29 and Mc-31 and pathomorphological spectrum of neoplastic growths. PMID- 4294789 TI - [Implantation and diffusion of live poliomyelitis Type I vaccine administered by the nasal or oral route in young children living in nurseries]. PMID- 4294790 TI - The effects of multiple and single administration of dimethylnitrosamine to hamsters. PMID- 4294791 TI - [Functional development of gastric mucosa in the golden hamster. II. Forestomach]. PMID- 4294792 TI - Experimental striatal necrosis induced by sodium azide. A contribution to the problem of selective vulnerability and histochemical studies of enzymatic activity. PMID- 4294794 TI - The adrenal cortical glucocorticoid function in asthmatic children. PMID- 4294793 TI - [On the enzyme histochemistry of meningiomas]. PMID- 4294795 TI - [On the flavonoids of a moraceous plant of the Ivory Coast: the Morus mesozygia Stapf]. PMID- 4294797 TI - Lactate dehydrogenase activity in the preimplantation rabbit embryo. PMID- 4294796 TI - Regulation of liver microsomal inorganic pyrophosphate-glucose phosphotransferase, glucose-6-phosphatase and inorganic pyrophosphatase. PMID- 4294798 TI - [Specificity of cerebral hemisphere glioma in children]. PMID- 4294799 TI - [2 cases of brain tumor in the neonatal period--review of the reported literature]. PMID- 4294801 TI - [The etiologic relations of infectious and chronic hepatitis]. PMID- 4294800 TI - [Isolation of enteroviruses and adenoviruses in diarrheas of childhood]. PMID- 4294802 TI - [On the mechanism of the toxic action of isopropyl-nitrite]. PMID- 4294803 TI - [The effect of adrenocorticotropic hormone on fibrinolysis, heparin level and blood antithrombin activity in rabbits]. PMID- 4294804 TI - [Studies on carbohydrate metabolism in the liver. 1. Patterns of glucose metabolizing enzymes in the liver in patients with hyperthyroidism]. PMID- 4294805 TI - [Studies on carbohydrate metabolism in the liver. 2. Patterns of glucose metabolizing enzymes in the liver in patients with liver disease]. PMID- 4294806 TI - Isolation of smallpox virus in monkey kidney tissue culture. PMID- 4294808 TI - [On the organization of care of acute cerebrocranial injuries]. PMID- 4294807 TI - [Pathogenesis of so-called cystic angioma of the liver induced in hamsters by polyoma virus infection]. PMID- 4294809 TI - [Influence of serotonin on the synaptic transmission in the sympathetic ganglia in conditions of experimental hyperglycemia and hypoglycemia]. PMID- 4294810 TI - [To the problem of enzymatic control of the extent of destruction of subcellular structures in the processus of homogenization]. PMID- 4294811 TI - [Mitotic cycle in mouse kidney cells cultures with and without chronic polyoma virus inoculation]. PMID- 4294812 TI - [On the activity of succinate dehydrogenase, ubiquinone reductase and cytochrome oxidase in peripheral blood leukocytes of healthy subjects]. PMID- 4294813 TI - [Comparative characterization of the acidic and enzymatic methods of RNA extraction from liver cells]. PMID- 4294814 TI - [On the effectiveness of DNA isolated from mouse ascites hepatoma as a carcinogenic agent]. PMID- 4294815 TI - [The effect of prolongators on the activity of hyperimmune foot-and-mouth disease serums]. PMID- 4294816 TI - [The study of the role of Ixodes as carriers of the foot-and-mouth disease virus]. PMID- 4294817 TI - [Isolation of the foot-and-mouth disease virus from the exhaled air of diseased animals]. PMID- 4294818 TI - [Utilization of cholesterol in experimental amebiasis in guinea pigs]. PMID- 4294819 TI - Urothelial implantation of Wilms' tumors. PMID- 4294821 TI - Effect of cookery and holding on hams and turkey rolls contaminated with Clostridium perfringens. AB - Canned hams, turkey rolls, and ground-beef casseroles were inoculated with a mixture of vegetative cells and spores of selected strains of Clostridium perfringens, in approximately known numbers. After cooking and holding at different temperatures for various times, samples of the food were plated directly on sulfadiazine-polymixin-sulfite-agar. In all cases, small but measurable percentages of the organisms survived cookery. The number of cells viable after cookery of the ham or turkey was influenced by the position of the slice of meat in the roast as well as by the final temperature to which the product was heated. Plate counts for turkey or beef casserole held at temperatures in the range of 5 to 10 C for 48 hr indicated stabilization of the population or a tendency to decrease. At 24 C, the multiplication of cells was apparent in 4 hr and rapid in 6 hr. When the food was maintained at 68 C, populations remained viable for 6 hr and the counts did not change markedly. In turkey maintained at 37 C, the number of cells increased sharply within 4 hr. PMID- 4294820 TI - Mechanism of the bactericidal action produced by electrohydraulic shock. AB - Electrohydraulic shock was shown to produce oxidation reactions which inactivated certain compounds important in cellular metabolism. Enzymes that were inactivated included lactic dehydrogenase, trypsin, and proteinases of Bacillus subtilis. Free sulfhydryl groups and reduced nicotinamide adenine dinucleotide were oxidized. Adenosine triphosphate was destroyed, but deoxyribonucleic acid was not affected. Intracellular material of Escherichia coli lost its ability to absorb at 260 mmu after electrohydraulic shock. The bactericidal mechanism involved appeared to be due to nonselective oxidation reactions produced by high-voltage discharges in water. These oxidation reactions were probably mediated by free radicals produced in the water. PMID- 4294822 TI - Carbon balance of a mannitol fermentation and the biosynthetic pathway. AB - The carbon balance was determined for a fermentation in which mannitol is produced from glucose by an Aspergillus species. The products found were: cells (17% of carbon input), CO(2) (26%), mannitol (35%), glycerol (10%), erythritol (2.5%), glycogen (1%), and unidentified compounds (8%). Thus, 92% of the carbon input was accounted for. Cell-free enzyme studies showed that mannitol was synthesized via the reduction of fructose-6-phosphate and not by the direct reduction of fructose. If the cell yield from glucose was assumed to be 50% and the theoretical conversion efficiency from glucose to polyols was 90%, as calculated from the energy balance, then 34% of the glucose carbon was used for growth and 53% was used for polyol formation. PMID- 4294823 TI - Treatment of mengovirus infection in mice with statolon. AB - A single intraperitoneal injection of statolon was shown to exert a therapeutic effect on mice previously injected with the large plaque-forming variant of mengovirus. The ld(50) and survival time data demonstrated that such treatment was effective when given 2 to 48 hr after infection. No protective effect was apparent when statolon was administered 3, 4, or 5 days after the viral challenge. It was concluded that statolon, or other similar interferon inducers, may be of therapeutic value in instances of accidental or other known exposure to hazardous viral agents. PMID- 4294824 TI - Prior breast disease in patients treated for papillary carcinoma. PMID- 4294825 TI - The effect of dietary protein on carcinogenesis of aflatoxin. PMID- 4294826 TI - Fatty inclusions and microcysts. Thioacetamide induced fatty inclusions in nuclei of mouse liver cells and hepatoma cells. PMID- 4294827 TI - [Exaggeration of the pressor response to angiotensin in a case of adrenal pheochromocytoma]. PMID- 4294828 TI - [Histological introduction to the study of secreting tumors of the hypophysis]. PMID- 4294829 TI - [Cushing's disease with melanodermia due to a hypophyseal melanotropic cell adenoma]. PMID- 4294830 TI - [Plasma ACTH in Cushing's disease with hypophyseal tumors]. PMID- 4294831 TI - Tachyphylaxis to alpha- and beta-angiotensin in dogs perfused with Ringer's solution or blood. PMID- 4294832 TI - A turbidimetric method for the determination of pentachlorophenol in urine. PMID- 4294834 TI - A program for the rehabilitation of socially disabled psychiatric patients through retraining. PMID- 4294833 TI - Odontogenic tumors. A survey of their manifestations in childhood. PMID- 4294835 TI - Carcinogenicity of organic extracts of atmospheric pollutants. PMID- 4294836 TI - Contagious ecthyma in man. Report of two cases with laboratory studies. PMID- 4294837 TI - The role of the ovarian stroma in hormone production by ovarian tumours. PMID- 4294838 TI - The response of isolated sheep and human umbilical arteries to oxygen and drugs. PMID- 4294839 TI - Effect of smoking and nicotine on adrenocortical secretion. PMID- 4294841 TI - [The study of the ACTH reserve potential of the adenohypophysis with pitressin tannate]. PMID- 4294840 TI - The value of neomycin in a neomycin-steroid cream. PMID- 4294842 TI - [Case of hypoharynx cancer due to irradiation presenting as pseudosarcoma]. PMID- 4294843 TI - [Hemostatic effect of conjugated estrogenic substances]. PMID- 4294844 TI - [Current status of the problem of rehabilitation of neurologic patients]. PMID- 4294845 TI - [Clinical considerations on the use of hypertensive drugs in spinal anesthesia]. PMID- 4294846 TI - Amino acid-activating enzymes in yellow lupin seeds, and purification of leucyl sRNA synthetase. PMID- 4294847 TI - Isolation and properties of soluble ribonucleic acid from yellow lupin seeds. PMID- 4294848 TI - Ribonucleic acid accompanying deoxyribonucleic acid in the course of extraction from rat brain. PMID- 4294849 TI - Secondary structure of poly-N(4),5-dimethylcytidylic acid and its copolymers with cytidylic acid. PMID- 4294850 TI - [Changes in the juxtaglomerular apparatus in experimental renovascular hypertension. I]. PMID- 4294851 TI - [Hypophyseal-adrenal regulation in congenital adrenal hyperplasia (study of plasma corticotropic activity in 24 patients)]. PMID- 4294852 TI - [Parathyroid activity and vitamin D. Observations on rats, chickens and guinea pigs]. PMID- 4294853 TI - [Hormonal interference with water and electrolyte metabolism in congestive heart failure]. PMID- 4294854 TI - Pathways of nicotinamide adenine dinucleotide biosynthesis in nicotinic acid or nicotinamide requiring microorganisms. PMID- 4294855 TI - Allosteric activation of DPN-linked malic enzyme from Escherichia coli by aspartate. PMID- 4294856 TI - Activation of adenyl cyclase in thyroid homogenates by thyroid-stimulating hormone. PMID- 4294857 TI - A beta-hydroxydecanoyl-ACP dehydrase specific for saturated fatty acid biosynthesis in E. coli. PMID- 4294858 TI - Branched-chain sphingosines from Tetrahymena pyriformis. PMID- 4294859 TI - [Determination of choleocalciferol (vitamin D3) in aqueous solutions on a thin layer]. PMID- 4294860 TI - [On the pathogenesis of experimental hepatitis in the mouse: inactivation of the MHV-3 virus by a substance present in the intestinal tissue of the normal mouse]. PMID- 4294861 TI - [Contribution to the study of the etiology of viral hepatitis]. PMID- 4294862 TI - Polyribosome patterns in EMC-virus infected Krebs-2 cells and cell extracts. PMID- 4294863 TI - Hydrolytic activity of muscle acyl phosphatase on 3-phosphoglyceryl phosphate. PMID- 4294865 TI - Presynaptic inhibition in crustacean muscle: axo-axonal synapse. PMID- 4294864 TI - Cholinergic actions related to paradoxical sleep induction in the mesencephalic cat. PMID- 4294867 TI - Failure of cortisone and ACTH to regulate cardiac hypertrophy. PMID- 4294866 TI - Structure activity relationships of compounds able to suppress the antipolio action of guanidine. PMID- 4294868 TI - [Infection and transformation of mouse embryo cells due to Harvey's murine sarcoma virus]. PMID- 4294869 TI - Effect of periodate on competence in Bacillus subtilis. PMID- 4294870 TI - Translation and polarity in the histidine operon. 3. The isolation of prototrophic polar mutations. PMID- 4294871 TI - Histidine regulatory mutants in Salmonella typhimurium. IV. A positive selection for polar histidine-requiring mutants from histidine operator constitutive mutants. PMID- 4294872 TI - Translation and polarity in the histidine operon. II. Polarity in the histidine operon. PMID- 4294873 TI - Experimental observations concerning the effects of mineral dust to pulmonary tissue. PMID- 4294874 TI - [On the intrabronchial treatment of bronchial adenoma. Report of a further case and follow-up of an earlier case]. PMID- 4294875 TI - Program evaluation and planning in a community mental health service. PMID- 4294876 TI - Schizophrenic patients in 1950-1952 and 1957-1959. A comparative study. PMID- 4294877 TI - A comparison of two populations within a psychiatric clinic. PMID- 4294878 TI - Intensive treatment of the chronic schizophrenic. PMID- 4294879 TI - Pancreatic tumor with intractable watery diarrhea, hypokalemia and hypercalcemia electrolyte balance studies. PMID- 4294880 TI - The effects of hydrocortisone and ACTH on the gastric mucosa of the rat. PMID- 4294881 TI - Microangiopathic haemolytic anaemia associated with consumption coagulopathy in a patient with disseminated carcinoma. PMID- 4294882 TI - The duration and control of adrenal function in adenohypophysectomized cockerels. PMID- 4294884 TI - Herpes encephalitis. PMID- 4294883 TI - Pathology of the kidney and liver in the experimental leptospirosis of the guinea pig. A light and electron microscopy study. PMID- 4294885 TI - Cushing's syndrome caused by bronchial adenomas. PMID- 4294886 TI - Primary mediastinal tumors. PMID- 4294887 TI - Early evaluation of peripheral nerve lesions in continuity with a note on nerve recording. PMID- 4294888 TI - Renin and angiotensin II studies in malignant hypertension after x-irradiation for seminoma. PMID- 4294889 TI - Islet cell tumors of the pancreas. PMID- 4294890 TI - Electron spin resonance of microsomal cytochromes. Correlation of the amount of CO-binding species with so-called microsomal e-x in microsomes of of Sudan III treated animals. PMID- 4294891 TI - The low-temperature spectral properties of mammalian cytochromes oxidase. II. The enzyme isolated from beef-heart mitochondria. PMID- 4294892 TI - Cytochrome oxidase and its derivatives. 8. Formation and properties of the 'oxygenated' form of cytochrome oxidase and its reconversion to ferrous and ferric oxidase. PMID- 4294894 TI - Testosterone and hydrocortisone-stimulated responses of reduced pyridine nucleotide fluorescence in prostates cultured from castrate rats. PMID- 4294893 TI - The action of amytal on frog gastric mucosa. PMID- 4294895 TI - Electron paramagnetic resonance studies on the cytochrome oxidase from yeast. PMID- 4294896 TI - A simplified procedure for the preparation of cytochrome oxidase by non-ionic detergent. PMID- 4294897 TI - Intracellular localisation of phosphoglycollate phosphatase and glyoxalate reductase. PMID- 4294898 TI - Isolation of high-molecular-weight NADH dehydrogenase of the respiratory chain by diethyl ether--Triton X-100 treatment. PMID- 4294899 TI - Chromatography of lipids. I. An improved chromatographic procedure for the quantitative isolation of the neutral ceramide-containing glycolipids from mammalian tissues. PMID- 4294900 TI - Chromatography of lipids. II. The quantitative isolation of the minor (acidic) phospholipids and of phosphatidylethanolamine from the lipid extracts of mammalian tissues. PMID- 4294901 TI - Palmitate and glucose metabolism in tumors induced by Rous sarcoma virus. PMID- 4294902 TI - Phospholipases in arterial tissue. I. Sphingomyelin cholinephosphohydrolase activity in human, dog, guinea pig, rat and rabbit arteries. PMID- 4294903 TI - Characteristics of rat liver phosphatidylinositol kinase and its presence in the plasma membrane. PMID- 4294904 TI - The phospholipid compositions of some Actinomycetes. PMID- 4294905 TI - Monophosphatidyl inositol inositolphosphohydrolase in guinea-pig brain. PMID- 4294906 TI - The unsaturated fatty acids of Escherichia coli. PMID- 4294907 TI - The effect of temperature on the formation of delta 5-unsaturated fatty acids by bacilli. PMID- 4294908 TI - Mammary tumor virus in a spontaneous transplantable male mammary tumor. PMID- 4294909 TI - Phagocytosis and degradation of elastin by normal and tumor cells in culture. PMID- 4294910 TI - Immunology of the mouse mammary tumor virus (MTV): neutralization of MTV by mouse antiserum. PMID- 4294912 TI - Defective dietary control of fatty acid metabolism in four transplantable rat hepatomas: numbers 5123C, 7793, 7795, and 7800. PMID- 4294911 TI - Studies on respiration and glycolysis in transplanted hepatic tumors of the rat. PMID- 4294913 TI - DNA metabolism in liver and kidney tumors of different growth rates. PMID- 4294914 TI - Effects of pharmacological agents on the physiological responses of hair discs. PMID- 4294915 TI - Physiological effects of corticosteroids on the eye. PMID- 4294916 TI - Pharmacological effects of corticosteroids. PMID- 4294918 TI - Use of corticosteroids in neuroophthalmology. PMID- 4294917 TI - Steroid therapy in uveitis. PMID- 4294919 TI - Cortisone glaucoma. PMID- 4294920 TI - Experimental enteritis with food poisoning and classical strains of Clostridium perfringens type A in lambs. PMID- 4294922 TI - Studies on the interaction between endotoxin and polymyxin B. PMID- 4294921 TI - Plasma enzyme changes in Listeria monocytogenes-infected mice. PMID- 4294923 TI - Intracranial extensions of juvenile angiofibroma of the nasopharynx. PMID- 4294924 TI - [Separation of bufo-steroids by eluting dry column chromatography on silica gel]. PMID- 4294925 TI - [Clinical study of cardiac asthma]. PMID- 4294926 TI - [Bronchial adenoma--recent experiences with 4 cases]. PMID- 4294928 TI - Influence of adrenocorticotrophic hormone (ACTH) on ovum-implantation induced by estradiol and progesterone in ovariectomized rats. PMID- 4294927 TI - Antigens of epithelial basement membranes of mouse, rat, and man. A study utilizing enzyme-labeled antibody. PMID- 4294929 TI - Pathological studies on bone marrow in equine infectious anemia. II. Histopathology of vertebral, sternal and femoral bone marrow. PMID- 4294930 TI - Equine infectious anemia occurring in Hokkaido, Japan--its histopathology and a critical view of the occurrence and diagnosis of this disease. PMID- 4294932 TI - [Primary carcinoma of the jejunum]. PMID- 4294931 TI - [Studies on the relation between clinical course and the mode of infiltration by the neoplasm in mammary cancer]. PMID- 4294933 TI - [Behavior of enzymes in liver cirrhosis induced with CCl-4 in rats]. PMID- 4294934 TI - [Cytodiagnosis of alveolar carcinoma of the lungs]. PMID- 4294935 TI - [Hypophosphatasia and vitamin D-resistant rickets]. PMID- 4294936 TI - [The role of neural factors in the pathogenesis of cortico-visceral disorders]. PMID- 4294937 TI - [Observations on pain]. PMID- 4294939 TI - [On the simultaneous loss of spontaneous automatic sound emission and speech]. PMID- 4294938 TI - [Combined culture of smallpox virus and avian pseudoplague virus and rate of multiplication of smallpox virus in different components of the embryonated egg]. PMID- 4294940 TI - Virus-like particles in human oral papilloma. PMID- 4294941 TI - [Our experience with chlorophyllated lipiodol in surgery]. PMID- 4294942 TI - Hypocalcemia and tetany with steroid-induced acute pancreatitis. PMID- 4294943 TI - Hepatic abscess: review of seven patients seen at Wilford Hall USAF Hospital, 1956-1966. PMID- 4294944 TI - [Quantitative determination of the silicogenous property of powders of different grain size and solubility in the liver-spleen test]. PMID- 4294945 TI - Allosteric properties of the Mg++-dependent inorganic pyrophosphatase in mouse liver cytoplasm. PMID- 4294946 TI - Basicity, visible spectra, and electron spin resonance of flavosemiquinone anions. PMID- 4294947 TI - Magnetic and spectrophotometric investigations of cytochrome b5. PMID- 4294948 TI - [Tuberculous encephalomeningitis and pregnancy]. PMID- 4294949 TI - Effect of lysine vasopressin dimer on corticotropin release in man. PMID- 4294950 TI - Coexistence of primary ovarian insufficiency, primary adrenocortical insufficiency and idiopathic hypoparathyroidism. PMID- 4294951 TI - The regional and subcellular distribution of 2',3'-cyclic nucleotide 3' phosphohydrolase in the central nervous system. PMID- 4294952 TI - Alterations in the activities of several rat liver enzymes at various times after initiation of a high protein regimen. PMID- 4294953 TI - A&UTORADIOGRAPHIC STUDIES ON DNA biosynthesis in Entamoeba histolytica in CLG medium. PMID- 4294955 TI - [The varicella-zoster virus]. PMID- 4294954 TI - Changes associated with parasitism in nematodes. II. Histochemical and microspectrophotometric analyses of preparasitic and parasitic larvae of Meloidogyne javanica. PMID- 4294956 TI - [On the importance of examining the reserve of the adrenal cortex with ACTH on the basis of determining dehydroepiandrosterone in urine during the course of radiotherapy]. PMID- 4294957 TI - [Contribution to the study of the reparative process of bone wounds. Treatment of experimental fractures with coadjuvant factors]. PMID- 4294958 TI - [Human angiotensin]. PMID- 4294959 TI - [Problems of activated peptides in pathogenetic analysis]. PMID- 4294960 TI - [Biochemistry of renin-angiotensin--with special reference to angiotensinase]. PMID- 4294961 TI - [Activity of renin-angiotensin in normal and abnormal conditions]. PMID- 4294962 TI - [Renal hypertensive factor and hypertension]. PMID- 4294963 TI - [Renin-angiotensin system and sympathetic nerve factors]. PMID- 4294964 TI - [Measurement of renin and angiotensin in the blood and renal renin]. PMID- 4294965 TI - [Measurement of renin and angiotensin in the blood and renal renin]. PMID- 4294966 TI - [Significance of renin-angiotensin determination]. PMID- 4294967 TI - [Measurement of renin and angiotensin in the blood and renal renin]. PMID- 4294968 TI - [Measurement of renin and angiotensin in the blood]. PMID- 4294969 TI - [Advantages and disadvantages of various methods of determination and our experiences]. PMID- 4294970 TI - [Measurement of renin and angiotensin in the blood and renal renin]. PMID- 4294971 TI - [Measurement of renin and angiotensin in the blood]. PMID- 4294972 TI - [Measurement of renin and angiotensin in the blood and in the kidney]. PMID- 4294973 TI - [Measurement of serum renin activity and its clinical significance]. PMID- 4294974 TI - [Problems of vascular reactivity in the development of hypertension]. PMID- 4294976 TI - [Immunological study of lipovirus]. PMID- 4294977 TI - [Trial on the isolation of human hepatitis virus]. PMID- 4294975 TI - [Clinical problems of polyenoic fatty acid from the surgical aspect. (3). Experimental and clinical studies on the development of cholesterol gall stone and the role of adrenal lipid]. PMID- 4294978 TI - [Suspected human hepatitis viruses]. PMID- 4294979 TI - [Suspected human hepatitis virus]. PMID- 4294980 TI - [Problems on suspected human hepatitis viruses: general discussion]. PMID- 4294981 TI - A simple chromatographic method for the estimation of small amounts of 17,21 dihydroxy-20-ketosteroids in urine. PMID- 4294982 TI - Properties of steroidal 3 enol heptafluorobutyrates. PMID- 4294983 TI - The products of methylation of the four estriol epimers by dimethyl sulfate. PMID- 4294984 TI - Microphysiology of vasopressors in shock. PMID- 4294985 TI - Susceptibility of Pseudomonas to colistin, kanamycin and polymyxin-B. PMID- 4294986 TI - Arrhenoblastoma. A case report. PMID- 4294987 TI - Granular cell myoblastoma of the vulva. PMID- 4294988 TI - Sedimentation coefficient of polyoma virus DNA. PMID- 4294989 TI - Muscle type isoenzymes of liver aldolase in hepatomas. PMID- 4294990 TI - Changes in DNA synthesis and cell proliferation during hepatocarcinogenesis by diethylnitrosamine. PMID- 4294991 TI - Cytochemical studies of some cytoplasmic structures in embryo and newborn rat liver and in hepatoma. PMID- 4294992 TI - Influence of cortisone and ACTH on the incorporation of S35 into the mucous cells of the intestine of albino rats. PMID- 4294993 TI - A clinico-pathological study of bone tumours. PMID- 4294994 TI - Cystosarcoma phyllodes. PMID- 4294995 TI - The suprarenal cortical function as measured by the plasma 17 hydroxycorticosteroid level in malnourished children. II. In kwashiorkor. PMID- 4294996 TI - A comparison of two neutralization methods for typing enteroviruses. PMID- 4294997 TI - The neurophysiological basis of motor learning. A review. PMID- 4294998 TI - Cylindroma of the trachea. PMID- 4294999 TI - [Surgical management of nontraumatic peripheral nerve pareses of extremities]. PMID- 4295000 TI - 18F scanning of primary and metastatic bone tumours. PMID- 4295001 TI - [Viral etiology of laryngeal papillomatosis]. PMID- 4295002 TI - [Apropos of the etiology of chronic bronchitis (importance of certain respiratory diseases of childhood)]. PMID- 4295004 TI - [Isolation and identification of the bovine strains of Myxovirus para-influenzae 3 in Czechoslovakia]. PMID- 4295003 TI - Differentiation between vibrio cholerae and Vibrio cholerae biotype El Tor by the polymyxin B disc test: comparative results with TCBS, Monsur's, Mueller-Hinton and nutrient agar media. PMID- 4295005 TI - [Hemagglutinin of Myxovirus para-influenzae. IV. Attempt at disintegration of the virus]. PMID- 4295006 TI - [The type of hereditary transmission in a case of hypophosphatasia]. PMID- 4295007 TI - Ascarosides and ascaroside esters in Ascaris lumbricoides (Nematoda). PMID- 4295008 TI - The transport of 14C-labelled material from CNS to and from muscle along a nerve trunk. PMID- 4295009 TI - Phospholipase activity in Musca domestica L. PMID- 4295010 TI - The influence of gonadal hormones and biotin deficiency upon liver lipid composition and liver fatty acid distribution in female chicks fed either a fat free or fat-supplemented diet. PMID- 4295011 TI - [On the problem of bovine leukosis]. PMID- 4295012 TI - Induction of "avian leucosis group-specific" antigen synthesis in chick embryo fibroblasts by template active RNA from avian myeloblastosis virus. PMID- 4295013 TI - Sporulation of mesophilic clostridia. PMID- 4295014 TI - [Experimental gastric pathology induced by glucocorticoids]. PMID- 4295015 TI - Killed fowl plague virus vaccine obtained from chick embryo cells. PMID- 4295017 TI - [Japanese B encephalitis]. PMID- 4295016 TI - [Carcinomas of the ovary. (Prognostic considertions)]. PMID- 4295018 TI - [Progess in the administration of adrenal cortical hormones]. PMID- 4295019 TI - [Amenorrhea and climacteric disorders]. PMID- 4295020 TI - [Myasthenia gravis]. PMID- 4295021 TI - Fundamental features of the "minimal deviation" hepatoma 5123. PMID- 4295022 TI - [Detection and distribution of the hydrolytic enzymes beta-D-glucuronidase, beta D-galactosidase, beta-D-glucosidase and arylsulfatase in intracranial tumors]. PMID- 4295023 TI - [Separation of nucleic acids by thin layer chromatography]. PMID- 4295024 TI - [Insignificance of nutritional condition of rats in the development of hepatoma by diethylnitrosamine]. PMID- 4295025 TI - [Influence of insulin on the enzymatic regulation of glycogenolysis]. PMID- 4295026 TI - [Amino acid dependent phosphate exchange between P32-pyrophosphate and ATP with extracts of pea root tissue]. PMID- 4295027 TI - Cellular neurophysiological approaches in the study of learning. PMID- 4295028 TI - Theory and practice of the rehabilitation of the psychiatrically disabled. PMID- 4295029 TI - [The clinical picture, diagnosis and treatment of maxillary cylindroma]. PMID- 4295030 TI - Effect of mechanoreceptor stimulations of different intensities originating from the stomach andlungs on the afferent impulsation of the cervical vagus. PMID- 4295032 TI - Aldosterone in childhood. PMID- 4295031 TI - Adrenergic neurone blocking agents of tropane and granatane structure. Their effect on the guinea pig vas deferens. PMID- 4295033 TI - Clinical evaluation of an intradermal skin test for amebiasis. PMID- 4295034 TI - Herpes virus in the lacrimal gland, conjunctiva and cornea of man--a chronic infection. PMID- 4295035 TI - The dynamics of adrenocortical secretion. PMID- 4295036 TI - Nursing referral outcome for post-hospitalized chronically ill patients. PMID- 4295037 TI - Zollinger-Ellison syndrome in a patient with multiple carcinoid-islet cell tumors of the duodenum. PMID- 4295038 TI - Studies on the structure of poliovirus. PMID- 4295039 TI - On the cpsid structure of some small feline and bovine RNA viruses. PMID- 4295040 TI - Susceptibility of rabbit kidney cells of various passage levels to infection with SV-40 virus. PMID- 4295041 TI - Determination of equine serum inhibitors for poliovirus by the gel-adsorption technique. PMID- 4295042 TI - The study of vesicular stomatitis viral components by x-irradiation. PMID- 4295043 TI - Posterior subcapsular cataracts and macular lesions after long-term corticotrophin therapy. PMID- 4295045 TI - [Description of the animal health situation in the Ivory Coast]. PMID- 4295044 TI - Corneal hypersensitivity to herpes simplex. PMID- 4295046 TI - Epidemiological study of Clostridium perfringens (welchii) food poisoning--the carrier state and its variation in humans. PMID- 4295047 TI - Leukemia: serial transplantation of human leukemic lymphoblasts in the newborn Syrian hamster. PMID- 4295048 TI - Kinetics and dissociation constants of liver alcohol dehydrogenase with 3-acetyl pyridine NAD+ and NADH. PMID- 4295050 TI - A study o DNA, partially denatured DNA and protein-DNA complexes in the polyethyleneglycol-dextran phase system. PMID- 4295049 TI - [On some lipid constituents of Corynebacterium ovis]. PMID- 4295051 TI - A fraction of newly synthesized DNA of HeLa cells. PMID- 4295052 TI - The role of phosphatidate phosphohydrolase in glyceride biosynthesis. PMID- 4295053 TI - Enzymatic synthesis of DNA with 4-thio-thymidine triphosphate as substitute for dTTP. PMID- 4295054 TI - Studies on phytosterol biosynthesis. The presence of 4-alpha,14-alpha-dimethyl delta-8,24(28)-ergostadien-3-beta-ol in grapefruit peel and its co-occurrece with cycloeucalenol in higher plant tissues. PMID- 4295055 TI - Evidence for a fastr degradation of an atypical hydroxyproline and hydroxylysine deficient collagen formed under the effect of 2,2'-dipyridyl. PMID- 4295056 TI - Significance of the so-called oval cell proliferation during azo-dye hepatocarcinogenesis. PMID- 4295057 TI - Histopathological study on early carcinoma of the stomach: some considerations on the ulcer-cancer by analysis of 144 foci of the superficial spreading carcinomas. PMID- 4295058 TI - Inhibition of alpha- and beta-hydroxysteroid dehydrogenases and steroid delta isomerase by substrate analogues. PMID- 4295059 TI - Rhinoviruses: basis for a numbering system. 1. HeLa cells for propagationand serologic procedures. PMID- 4295060 TI - Rhinoviruses: basis for a numbering system. II. Serologic characterization of prototype strains. PMID- 4295061 TI - The pathogenicity in mice of aerosols of encephalomyocarditis group viruses or their infectious nucleic acids. PMID- 4295062 TI - Studies of live attenuated Japanese encephalitis vaccine in swine. PMID- 4295063 TI - Histogenesis of malignant liver tumors induced by dimethylnitrosamine. An experimental study in Syrian hamsters. PMID- 4295064 TI - Study of S91 mouse melanomas by electron paramagnetic resonance (EPR) spectroscopy and tissue culture. II. Effects of penicillamine on EPR signals and on growth in vitro. PMID- 4295065 TI - "Minimal deviation" hepatomas: a critical review of the terminology, including a commentary on the correlation of enzyme activity with growth rate of hepatomas. PMID- 4295066 TI - Biophysical and bioassay studies on milk fractions of genetically similar agent bearing agent-free mouse substrains. PMID- 4295067 TI - Studies on acute leukemia and infectious mononucleosis of childhood. I. Viral interference with lymphoblastoid cells of spontaneously transformed bone marrow cultures. PMID- 4295068 TI - Antibodies for Rous sarcoma virus (Bryan) in fowl, animal, and human populations of East Africa. II. Antibodies in domestic chickens, wildfowl, primates, and man in Kenya, and antibodies for Burkitt lymphoma cells in man. PMID- 4295069 TI - Bone marrow colony-stimulating activity of serum from mice with viral-induced leukemia. PMID- 4295070 TI - [The change in the content of 17-oxycorticosteroids in the urine of bronchial asthma patients]. PMID- 4295071 TI - [The functional status of the adrenal cortex in patients with diffuse diseases of the kidneys before and after corticosteroid therapy]. PMID- 4295072 TI - Discrete potentials in the dark-adapted ye of the crab Limulus. PMID- 4295073 TI - Deficiency of erythrocyte nicotinamide adenine dinucleotide nucleosidase (NADase) activity in the Negro. PMID- 4295074 TI - Influence of positive inotropic agents on the action of a myocardial depressant factor in the plasma of cats in postoligemic shock. PMID- 4295075 TI - Effect of hyperthermia on blood platelets in male rats. PMID- 4295076 TI - Ribonucleic acid synthesis and nuclear ribonucleic acid polymerase activity in livers of mice infected with mouse hepatitis virus (MHV-3). PMID- 4295077 TI - Plaques of rhinoviruses in human diploid cells. PMID- 4295078 TI - DNA biosynthesis in monkey kidney cells infected with PARA (SV40)-adenoviruses. PMID- 4295080 TI - Plaque assay for herpes simplex virus in L-929 (Earle) mouse fibroblasts. PMID- 4295079 TI - Effect of streptovitacin A on replication of an RNA virus (poliovirus). PMID- 4295081 TI - [Effect of culinary processes on the content of phytin compounds in some groats and flakes]. PMID- 4295082 TI - [Studies on te effects of renin on the development of hypertension]. PMID- 4295083 TI - Racial and prenatal factors in major congenital malformations. PMID- 4295084 TI - Wilms' tumor and neurblastoma. PMID- 4295085 TI - Renal artery constriction: physiological determinants of pressure gradients. PMID- 4295086 TI - Anomalous response of certain chicken embryo to various inocula. II. Evidence of a biological agent associated with resistance to rous sarcoma virus infection. PMID- 4295087 TI - Pituitary and adrenal influence on reduced insulin B-chain induced hyperglycemia. PMID- 4295088 TI - Insulin secretion by insuloma and normal pancreas slices. Studies in a patient with multiple endocrine adenomata. PMID- 4295089 TI - [On steroid-Konjugate in Plasma. XX. c5*163-5* A/Oertel GW, Treiber L: [On steroid conjugates in plasma. XX. In vitro biosynthesis o androstendione from 3H- and 35S-labelled androstenolone sulfoconjugates]. PMID- 4295090 TI - [Kinetics of the formation of semidehydroascorbic acid]. PMID- 4295091 TI - Asparagine biosynthesis by the Novikoff Hepatoma isolation, purification, property, and mechanism studies of the enzyme system. PMID- 4295092 TI - Citryl 1-phosphate and the citrate cleavage reaction. PMID- 4295093 TI - Nephrotic syndrome and nephroblastoma. Report of a case. PMID- 4295094 TI - Thermal conductivity of glycine. PMID- 4295095 TI - Electron spin resonance and optical spectra of haemoglobin-M Hyde Park. PMID- 4295096 TI - Activation of glucose-6-phosphatase of rat liver at high pH: differential response of basal and induced activities. PMID- 4295097 TI - Virilizing lipoid cell tumor of the ovary. Report of 2 cases, 1 with uterine hypertrophy. PMID- 4295098 TI - Meigs-like syndrome secondary to Krukenberg's tumor. PMID- 4295099 TI - Theca cell tumor associated with pregnancy. Report of acase. PMID- 4295100 TI - [A case of progressive systemic sclerosis with broncho-alveolar cancer]. PMID- 4295101 TI - Immunopathological aspects in endocrine disorders (adrenals and pituitary gland). PMID- 4295102 TI - Acute necrotizing encephalitis: observations of herpes-like particles by electron microscopy. PMID- 4295103 TI - Effect of cortisone on nonfatal mouse cytomegalovirus infection. PMID- 4295104 TI - Cytopathic effects of parainfluenza virus Type 3 in organ cultures of human respiratory tract tissue. PMID- 4295105 TI - Collagenolytic activity in the rabbit and sow Graafian follicle during ovulation. PMID- 4295106 TI - A silica-gel trap system for dehumidification of expired gases in a nonrebreathing anesthetic or respiratory circuit. PMID- 4295107 TI - [Benign tumors of the tracheo-bronchial tree]. PMID- 4295109 TI - [Histological and histochemical study of structural changes of the capillaries in the synovial membrane during aspecific phlogosis]. PMID- 4295108 TI - [Further research on enzymatic embryology at the very beginning of development]. PMID- 4295110 TI - [Subungual glomus tumor. (Case report)]. PMID- 4295111 TI - Effect of angiotensin amide on sodium isotope flux and short-circuit current of isolated frog skin. PMID- 4295112 TI - Effect of aortic constriction on renin secretion in normal and hypophysectomized dogs. PMID- 4295113 TI - A cyclic phosphodiesterase with 3'-nucleotidase activity from Proteus mirabilis. PMID- 4295114 TI - Comparisons of the effects of Bacillus subtilis protease, type VIII (subtilopeptidase A), and insulin on isolated adipose cells. II. Antilipolytic action. PMID- 4295115 TI - Effect of metyrapone on the excretion of oestrogen in man. PMID- 4295116 TI - Association of antigenic type of Herpesvirus hominis with site of viral recovery. PMID- 4295117 TI - Emile Vidal (1825-1893), Parisian dermatologist. PMID- 4295118 TI - [Reticulosarcoma evolving from mixed tumor of the parotid gland]. PMID- 4295119 TI - [Cicatricial tumors of the lung]. PMID- 4295120 TI - Murine hepatitis virus: effect on liver RNA. AB - After infection of mice with hepatitis virus MHV3, the RNA in the liver undergoes changes. The fraction extracted with phenol at 0 degrees C does not alter. However, the fraction extracted with hot phenol at elevated pH (60 degrees C, pH 8.3) shows a 16S peak on sucrose-density-gradient centrifugation. This fraction shows actinomycin D-resistant incorporation of C(14)-orotic acid in infected but not in control livers-possible evidence of the RNA nature of MHV3. PMID- 4295121 TI - [On Wilms' tumor]. PMID- 4295122 TI - Immunization of horses against African horse-sickness with attenuated neurotropic viral strains propagated in chicken embryos. PMID- 4295123 TI - Assessment of pituitary-adrenal gland function in the dog. PMID- 4295124 TI - Eccrine glands of the rat. Response to induced sweating, hypertension, uremia, and alterations of sodium state. PMID- 4295125 TI - Klinefelter's syndrome and cancer of the breast. PMID- 4295126 TI - [Investigation of the rat liver for non-specific and tumor specific metabolic changes after administration of diethylnitrosamine (DENA)]. PMID- 4295127 TI - Pathology of ovarian neoplasms in rats and mice. PMID- 4295128 TI - Simultaneous fluorometric determination of cortisol and corticosterone in human plasma. PMID- 4295129 TI - Hypoglycemia in a two-year-old boy with adrenocorticotropic hormone (ACTH) deficiency (probably isolated) and adrenal medullary unresponsiveness to insulin induced hypoglycemia. PMID- 4295130 TI - Congenital adrenal hyperplasia due to a deficiency of one of the enzymes involved in the biosynthesis of pregnenolone. PMID- 4295131 TI - Gonadotropin-dependent Krukenberg tumor causing virilization during pregnancy. PMID- 4295132 TI - Characterization and source of a renin-like enzyme in anephric humans. PMID- 4295133 TI - Adrenocortical failure in panhypopituitarism. PMID- 4295134 TI - Adrenal function in patients treated with testosterone and fluorinated pyrimidines. PMID- 4295136 TI - Herpes simplex encephalitis. PMID- 4295135 TI - Cariostatic effect of a stannous fluoride-containing dentifrice on children: two year report of a supervised toothbrushing study. PMID- 4295137 TI - Cranial nerve syndromes. Relation to exogenous and endogenous substances. PMID- 4295138 TI - Outpatient treatment of a third degree burn. PMID- 4295139 TI - The auriculo-temporal or Frey syndrome and tympanic neurectomy. PMID- 4295140 TI - Cardiac rehabilitation. 3. Follow-up after myocardial infarction. PMID- 4295141 TI - The renin-angiotensin system and hypertension. PMID- 4295142 TI - Brotherly lumps. Familial occurrence of chemodectoma. PMID- 4295143 TI - [Study of aldosterone metabolism in a case of congenital nephrogenic diabetes insipidus]. PMID- 4295144 TI - Ultrasonic selective hypophysectomy. PMID- 4295145 TI - Cytolytic toxins of bacterial origin. The nature and properties of cytolytic proteins are discussed with emphasis on staphylococcal alpha-toxin. PMID- 4295146 TI - Corticotropin release: inhibition by intrahypothalamic implantation of atropine. AB - Anterior hypothalamic implantations of crystalline atropine markedly inhibit the adrenocortical responses evoked by surgical stress, ether anesthesia, or intravenolus injection of arginine vasopressin. Similar implants in nearby regions of the brain or sham implantations in the same region were ineffective. The data suggest that the hypothalamic control of pituitary corticotropin may have a cholinergic component. PMID- 4295147 TI - Carcinogens 3,4-benzpyrene and 3-methylcholanthrene: induction of mitochondrial oxidative enzymes. AB - Sections of liver from rats injected with 3,4-benzpyrene and 3 methylcholanthrene, when incubated in mediums specific for the histochemical demonstration of mitochondrial oxidative enzymes, show greater activity of several of these enzymes than do sections from control rats. This observation was confirmed by comparison of the staining of mitochondria isolated from the control and from "induced" rats. The fact that an inhibitor of protein synthesis, actinomycin D, effectively diminished the stimulation provided evidence that the stimulation of activity is due to an increase in enzyme synthesis, generally called induction. PMID- 4295148 TI - Experimental stromal herpes simplex keratitis in rabbits. PMID- 4295149 TI - Denervation atrophy in isoniazid polyneuropathy. Histo-enzymatic study. PMID- 4295150 TI - [The diagnosis and prognosis of gliomas of the cerebral hemispheres after a study of 245 cases]. PMID- 4295151 TI - [Selective brain-cooling]. PMID- 4295152 TI - [Morphologic and histochemical characteristics of lipids of interrenal tissue from some urodelous salamandridae]. PMID- 4295153 TI - [Autoradiographic aspects of follicular function in colloid goiter]. PMID- 4295154 TI - [Familial gynecomastia with hypospadias: Reifenstein's syndrome]. PMID- 4295155 TI - Electron spin resonance studies on heart muscle succinic dehydrogenase under low partial pressures of oxygen. PMID- 4295156 TI - An electron paramagnetic resonance study of nitric oxide hemoglobin derivatives. PMID- 4295157 TI - Fluorofumarate--a substrate for fumarate hydratase. PMID- 4295158 TI - Charge-transfer character of glucose dehydrogenase inhibition by substituted pyridines. PMID- 4295159 TI - [Presence and regulation of the synthesis of two alcohol dehydrogenases in the yeast Saccharomyces cerevisiae]. PMID- 4295160 TI - [Arginine oxygenase (decarboxylating). V. Purification and flavin nature]. PMID- 4295162 TI - The effect of angiotensin on renal carbonic anhydrase. PMID- 4295161 TI - Hg2+-induced dissociation of exchange reactions from catalytic activity of 2,3 diphosphoglycerate-dependent phosphoglyceromutases. PMID- 4295163 TI - Are 5-hydroxytryptamine and noradrenaline inhibitory transmitters in the medial geniculate nucleus? PMID- 4295164 TI - [On prolonged untreated cancer of the milk duct]. PMID- 4295165 TI - Prospects for radiation treatment of herpetic and other affections of the anterior segment of the eye. PMID- 4295166 TI - [Neurological complications of acute leukemia]. PMID- 4295167 TI - [Histomorphological and histoenzymatic changes of the ovary and uterus of the adult rat after epiphysectomy]. PMID- 4295168 TI - Adsorbent as a variable in thin-layer chromatography of Elapidae venoms. PMID- 4295169 TI - [A COMPARISON OF COLLAGEN STABILITIES OF & FROG SPECIES DIFFERING BY THEIR THERMOPHILY]. PMID- 4295170 TI - [On neurohumoral regulation of the function of the skin in practically healthy man]. PMID- 4295171 TI - [Influence of angiotensin on the distribution of cardiac output in normotensive subjects]. PMID- 4295172 TI - [Correlation between the catalase activity and resistance to drugs in Mycobacterium tuberculosis circulating in Southeast Africa]. PMID- 4295173 TI - Effect on adrenal steroid secretion of changes in renal haemodynamics in the rat. PMID- 4295174 TI - The effect of angiotensin on renal circulation during mannitol diuresis. PMID- 4295175 TI - LTH production and steroid excretion during the menstrual cycle. PMID- 4295176 TI - Influence of phosphate compounds on certain fungi and their preservative effects on fresh cherry fruit (Prunus cerasus, L.). AB - Studies were conducted to ascertain the retarding effects of four phosphate compounds (sodium hexametaphosphate, sodium tripolyphosphate, sodium tetraphosphate, and tetrasodium pyrophosphate) on molding of fresh cherries (Prunus cerasus, L.). In vitro studies on their antimycotic effects against the most common fungal spoilers, Penicillium expansum, Rhizopus nigricans, and Botrytis sp., were also carried out. Sodium tetraphosphate appeared to be the most effective compound in preserving cherries and also had the greatest antimycotic effects in the in vitro studies. A 10% concentration, when applied as a dip, inhibited fungal growth on fresh cherries for up to 30 days of storage at 1.1 C (34 F) and a relative humidity of 94%, whereas untreated controls showed fungal growth at 14 days. Following in order of effectiveness were sodium hexametaphosphate, sodium tripolyphosphate, and tetrasodium pyrophosphate. PMID- 4295177 TI - Production of specific varicella antiserum. PMID- 4295178 TI - Respiratory chain of antimycin A-producing Streptomyces antibioticus. AB - An active respiratory chain system was demonstrated in sonically treated mycelium of Streptomyces antibioticus, the producer of antimycin A. The respiratory electron transfer from substrate to oxygen proceeded successively through flavoprotein(s), b-, c-, and a-type cytochromes, and terminated with the cyanide sensitive cytochrome oxidase. The cytochrome composition of the culture was not affected by the age of the mycelium, the intensity of antimycin A production, or differences in the media. Slater factor, coenzyme Q, and vitamin K were not interposed as hydrogen carriers in the respiratory chain between flavoproteins and cytochromes. The oxidation of reduced nicotinamide adenine dinucleotide and succinate was unaffected by antimycin A. Evidence is presented in support of the absence of the antimycin A-sensitive site from the electron transport system of S. antibioticus. PMID- 4295179 TI - Improved medium for sporulation of Clostridium perfringens. AB - An improved sporulation medium has been developed in which all five strains of Clostridium perfringens tested exhibited a 100- to 10,000-fold increase in numbers of spores when compared with spore yields in SEC medium under comparable conditions. In addition, three of five strains produced a 100- to 1,000-fold increase, with the remaining two strains yielding approximately the same numbers of spores, when compared with strains cultured in Ellner medium. At the 40-hr sampling time, 18 of 27 strains produced a 10- to 100-fold increase in numbers of spores in our medium, when compared to spore production obtained in a medium recently reported by Kim et al. The new medium contained yeast extract, 0.4%; proteose peptone, 1.5%; soluble starch, 0.4%; sodium thioglycolate, 0.1%; and Na(2)HPO(4). 7H(2)O, 1.0%. In some cases, the spore yield could be increased by the addition of activated carbon to the new medium. The inclusion of activated carbon in the medium resulted in spores with slightly greater heat resistance than spores produced in the new medium without added carbon or in SEC or in Ellner medium. The major differences in heat resistance of the various strains appeared to be genetically determined rather than reflections of a particular sporulation medium. A definite heat-shock requirement was shown for four of four strains, with the optimal temperature ranging from 60 C for a heat-sensitive strain to 80 C for a heat-resistant strain. Heating for 20 min at the optimal temperature resulted in a 100-fold increase over the viable count obtained after heating for 20 min at 50 C. PMID- 4295180 TI - [Contribution to the knowledge of primary malignant tumors of the hepato-cystic choledochal junction]. PMID- 4295181 TI - A study of cortisol metabolism in patients with chronic asthma. PMID- 4295182 TI - The lipids in fossils. PMID- 4295183 TI - Gastric suphilis: a case with pernicious anemia. PMID- 4295184 TI - [Conjugation of hydrocortisone-4-C14 under the influence of endocrine stimulation]. PMID- 4295185 TI - [On the problem of the "rebound"-shift in the adrenal cortex following ACTH]. PMID- 4295187 TI - [Ossification of the epiphyseal cartilages of the elbow joint]. PMID- 4295186 TI - Paradoxical increase of peripheral glucose utilization in a patient with insulinoma treated with prednisolone. PMID- 4295188 TI - Emergency liver resection for primary carcinoma. PMID- 4295189 TI - [Photochemical activity of isolated chloroplasts]. PMID- 4295190 TI - [Adrenal cortex function in patients with peptic ulcer]. PMID- 4295191 TI - [On the distribution of nervous system diseases among the population of an industrial city]. PMID- 4295192 TI - [Ischemic diseases of the nerve trunks]. PMID- 4295193 TI - [Thin layer chromatographic studies on the excretion of some phenol- and indol acids in urine]. PMID- 4295194 TI - [Determination of triglycerides in serum with Hantzsch's reaction]. PMID- 4295195 TI - [Studies on the mechanism of delayed hypersensitivity. I. Significance of the readiness for a delayed reaction in PCA reactions]. PMID- 4295196 TI - [Provocation of an infection through vaccination. X. Prevention of viral infection provocation through oral immunization with inactivated virus during the incubation period]. PMID- 4295197 TI - [A thermostable inhibitor in swine serum against foot-and-mouth disease virus. II. Resistance to treatments which destroy precipitated or absorbed inhibitors]. PMID- 4295198 TI - Hypothalamic centers regulating the secretion of adrenal corticoids. PMID- 4295199 TI - [The behavior of autonomic centers after introduction of thyrotropic hormone in the dog and guinea pig]. PMID- 4295200 TI - [Differential diagnostic possibilities in peripheral neurology with the aid of the ninhydrin test]. PMID- 4295201 TI - Synchronous behavior pattern of key glycolytic enzymes: glucokinase, phosphofructokinase, and pyruvate kinase. PMID- 4295202 TI - Plasma growth hormone responses and growth retardation of hypothyroidism. PMID- 4295203 TI - The role of host factors in mouse trophoblastic tissue growth. PMID- 4295204 TI - Granular cell myoblastoma of the clitoris. PMID- 4295205 TI - [Influence of inactivation with hydroxylamine on the antigenicity of poliomyelitis N-antigen]. PMID- 4295206 TI - [Changes in brain transit time in brain and nervous diseases--measurement of brain hemodynamics using isotopes]. PMID- 4295207 TI - Glycogen content of the cerebral cortex of hyperthermia and hypthermia generated by environmental conditions and administration of several drugs. PMID- 4295208 TI - The chemical composition of the cytoplasmic membrane of Bacillus subtilis. PMID- 4295209 TI - Carcinogenesis in different animal specids by diethylnitrosamine. PMID- 4295210 TI - Cytochemical studies of polyoma virus infection. 3. Deoxyribonuclease II. PMID- 4295211 TI - Cytochemical studies of polyoma virus infection. IV. Enzymatic digestion of nucleic acids. PMID- 4295212 TI - Changes in the activity of intracellular enzymes in neurogenic muscle atrophy. PMID- 4295213 TI - Histochemical studies of KB cell cultures infected with parainfluenza 3 virus. II. The activity of lysosomal and oxidative enzymes in virus-infected cells. PMID- 4295215 TI - Chromosomal analysis of ninety-one primary Rous sarcomas in the mouse. PMID- 4295214 TI - Double-minutes--a chromosomal aberration in Rous sarcomas in mice. PMID- 4295216 TI - Adrenocortical influences on free-operant avoidance behavior. AB - Rats were conditioned to avoid shock on a free-operant avoidance schedule in which no exteroceptive stimulus signaled impending shock. Injections of adrenocorticotropic hormone (ACTH) or dexamethasone raised blood levels of glucocorticoids. These increases were accompanied by changes in avoidance performance: there was a higher frequency of long-duration interresponse times, a greater stability among them, and fewer short interresponse times, total responses, and shocks. PMID- 4295217 TI - 7-deazaadenine ribonucleosides. The use of periodate oxidation in degradation studies. PMID- 4295218 TI - Transport of noradrenaline and dopamine-beta-hydroxylase in sympathetic nerves. PMID- 4295219 TI - A drug to beat viruses. The story of methisazone. PMID- 4295220 TI - [Corticoid treatment of lupus]. PMID- 4295221 TI - [On the diagnosis and therapy of chronic pressure damage to the peripheral nerves]. PMID- 4295222 TI - Myxoviruses and infections of the nervous system. PMID- 4295223 TI - Additional data on measles virus antibody and antigen in subacute sclerosing panencephalitis. PMID- 4295224 TI - Pathogenesis of viral infections of the nervous system. PMID- 4295225 TI - [New data on the etiopathogenesis of prostatic cancer]. PMID- 4295226 TI - [Chronic digestive disorders of vagotomized patients]. PMID- 4295227 TI - The metabolism of 11-dehydrocorticosterone by frog adrenal glands. PMID- 4295229 TI - [Rheological properties of desoxyribonucleoprotein of some animal tissues treated by blastomogenic agents]. PMID- 4295228 TI - [Abdominal injury]. PMID- 4295230 TI - [Contagious abortion caused by viruses in mares. Protocol of the course of the spread of an ERP epidemic on a trotting horse stud farm]. PMID- 4295231 TI - [Urological neoplasms and enzymes. II. Serum LDH, ALP, LAP, TAP and PAP activities and LDH isozymes in patients with neoplasms of the genitourinary organs]. PMID- 4295232 TI - Endolymphatic therapy for malignant melanoma. PMID- 4295233 TI - Acute necrotizing encephalitis. PMID- 4295234 TI - Disease from monkeys. PMID- 4295235 TI - Dysmenorrhoea. PMID- 4295236 TI - Pathophysiology and therapy of the fasting hypoglycemias. PMID- 4295237 TI - Studies on polypeptides. XXXIX. Elimination of the imidazole portion of histidine as an essential site for biological function of angiotensin. PMID- 4295238 TI - [Isolation of tubercle bacilli resistant to kanamycin or viomycine from tuberculous patients]. PMID- 4295239 TI - Regulation of Staphylococcus aureus lactate dehydrogenase. AB - The effect of growth conditions on the specific activity of nicotinamide adenine dinucleotide (NAD)-linked lactate dehydrogenase (LDH) in extracts of Staphylococcus aureus strain SG 511A was examined. Kinetic and electrophoretic experiments, with extracts prepared from aerobically and anaerobically grown cells, provided evidence for only one physiologically significant enzyme. The aerobic level of NAD-linked LDH of S. aureus remained constant and was independent of the carbon source. In contrast, the level of LDH produced in an anaerobic environment was variable and was dependent on the carbon source. Growth anaerobically on pyruvate, as the sole fermentable carbon source, resulted in a maximal level of LDH activity, a value about eightfold greater than the aerobic level. Anaerobic growth either on pyruvate plus glucose or on glucose alone, however, resulted in approximately a threefold decrease in this maximum. Experiments with a heme-requiring auxotroph derived from S. aureus demonstrated that the aerobic level of LDH activity was dependent on a functional respiratory chain. PMID- 4295241 TI - [An improved method for histochemical demonstration of uridine diphosphate glucose-glycogen glucosyltransferase]. PMID- 4295240 TI - Lactate dehydrogenase activity in certain strains of Staphylococcus aureus. AB - Lactate dehydrogenase (LDH) was studied in phage-propagating strains 29, 3A, 6, 81, and 42D of Staphylococcus aureus selected from the five groups in the International-Blair series. Cells were cultivated in Brain Heart Infusion (Difco) under nearly anaerobic conditions and were harvested near the end of the log phase. LDH activity was maximal at the end of the exponential growth period and was measured spectrophotometrically by reduction of p-nitro-blue tetrazolium, with phenazine methosulfate as a coupling agent. Crude enzyme extracts were prepared both by an acetone extraction technique and by sonic treatment. LDH activity for these enzyme preparations was determined by the colorimetric method mentioned and also by measuring the rate of nicotinamide adenine dinucleotide reduction at 340 mmu. The order of activity observed, by use of both assay methods, was 29 > 81 > 6 > 3A > 42D. LDH forms (possibly isoenzymes) for each of 15 strains, which represent the five phage-propagating groups of the International-Blair series, were separated by acrylamide gel electrophoresis. Five forms were distinguished and arbitrarily numbered on the basis of their rate of migration, no. 5 being the slowest component. No one strain had more than four, nor fewer than two, LDH forms. Form 3 appeared in 13 of the 15 strains and was followed in frequency by no. 2, 1, 4, and 5. PMID- 4295242 TI - Structure of viruses of the papilloma-polyoma type. IV. Analysis of tilting experiments in the electron microscope. PMID- 4295243 TI - [4 cases of breast cancer in the male]. PMID- 4295244 TI - Effect of starvation on the in vivo metabolism and effect of drugs in female and male rats. PMID- 4295246 TI - Case records of the Massachusetts General Hospital. Case 52-1967. PMID- 4295245 TI - The antibiotic sensitivity of Bordetella in South Australia. PMID- 4295247 TI - [Enzyme system in fatty acid mobilization]. PMID- 4295248 TI - Adrenal cortical function as reflected by the plasma hydrocortisone and urinary 17-ketogenic steroids in relation to surgery in elderly patients. PMID- 4295249 TI - Interference of phenoxybenzamine and guanethidine with the vasoconstrictor responses of noradrenaline and angiotensin II in the hand. PMID- 4295250 TI - Studies on the metabolism of chlorprothixene (Truxal) in rats and dogs. PMID- 4295251 TI - Quantitative analysis of sulfolipid (sulfoquinovosyl diglyceride) and galactolipids (monogalactosyl and digalactosyl diglycerides) in plant tissues. PMID- 4295252 TI - [The enzymes of barley and malt]. PMID- 4295253 TI - [Enzymes and evolution of the industrial value of potatoes]. PMID- 4295254 TI - [Treatment of acute diarrhea in infants with polymyxin B]. PMID- 4295255 TI - [Action of Entamoeba histolytica on live-human leucocytes]. PMID- 4295256 TI - A histological study of the effects of the herpesvirus of infectious bovine rhinotracheitis in the lactating bovine mammary gland. AB - Mastitis was produced in three first calf heifers by inoculation of the udder with the virus of infectious bovine rhinotracheitis. These animals were killed at different times during the course of the disease and tissues were harvested and examined histologically. The basic lesion resulted from the necrotizing effect of the virus upon the epithelial cells of the alveoli and ducts. Eosinophilic intranuclear inclusion bodies were demonstrated in tissues from animals killed at three and six days postinoculation, but not at nine days. Of interest was the presence of a large Reed-Sternberglike cell in tissues of the last two animals killed. PMID- 4295257 TI - [First experiences in the treatment of cerebral vascular accidents with the anti edema method of Bernard Weil]. PMID- 4295258 TI - Problems of establishing the etiologic roles of hepatitis "candidate" viruses. PMID- 4295259 TI - [On some immunological aspects of viral hepatitis]. PMID- 4295260 TI - [Behavior of the "enzymo-plasmatic syndrome" of mice infected with EFH 120 virus and subjected to lysozyme treatment]. PMID- 4295261 TI - Electron microscopic study on the ascites hepatoma--comparative observations. PMID- 4295262 TI - [Studies on experimental bone tumors (intramedullary transplantation of ascites hepatoma 130 in the rat's femur)]. PMID- 4295263 TI - Observation of changes in volume of a congested limb as a means of studying the behaviour of capacity vessels. AB - 1. Experiments have been performed to determine whether the volume of a forearm congested by a cuff inflated to a low pressure (15-30 mm Hg) reflects active changes in the vascular capacity of the part while remaining relatively insensitive to the passive effects of changes in perfusion.2. Conditions were chosen in which existing evidence suggests that blood flow and capacity vary independently of each other.3. The results of these experiments suggested that active changes in capacity can be studied by the continuous observation of the volume of a congested limb, provided that the associated change in blood flow is a reduction from the basal level and is not an increase above the basal level. PMID- 4295264 TI - [Study on hemolytic Streptococcus. 1. Streptococcal DPNase and antistreptococcal DPNase]. PMID- 4295265 TI - [Study on hemolytic Streptococcus. 2. Sensitization experiments with its exotoxins]. PMID- 4295266 TI - [Plasmatic angiotensinase activity in subjects with arterial hypertension of the essential type and of renal origin]. PMID- 4295267 TI - [Effectiveness of treatment of colienteritis in children with polymyxin M combined with furazolidon]. PMID- 4295268 TI - [Carcinoma of the anal gland]. PMID- 4295269 TI - Cyclic thrombocytopenia of acute type. PMID- 4295270 TI - [A comparative cytochemical study of Amoeba proteus adapted to different temperatures]. PMID- 4295271 TI - [Enzymologic study of the state of rat liver mitochondria after acute poisoning by thioacetamide, carbon tetrachloride and ethionine]. PMID- 4295272 TI - [Analysis of the action potentials led from the surface of the masseter in the frog]. PMID- 4295273 TI - [Chromosomal studies on xenogeneic transplantation of virus-induced tumor]. PMID- 4295274 TI - [Brain mechanisms for taste preference behavior]. PMID- 4295275 TI - [Information through chorda tympani and lingual nerve concerning intake of taste solutions]. PMID- 4295276 TI - Tumours of salivary glands. PMID- 4295277 TI - [Histochemical findings of mucopolysaccharides in pleomorphic adenoma (mixed tumor) of the human parotid gland]. PMID- 4295278 TI - Craniosynostosis. Review of the literature and indications for surgery. PMID- 4295279 TI - Experience with a human cytomegalovirus complement fixing antigen. PMID- 4295280 TI - The isolation of vesiculay stomatitis virus (Indiana strain) and other viruses from mosquitoes in New Mexico, 1965. PMID- 4295281 TI - Strategic viral surveillance of sewage during and following an oral poliovirus vaccine campaign. PMID- 4295282 TI - The virus watch program: a continuing surveillance of viral infection in metropolitan New York families. V. Observations in employed adults on etiology of acute upper respiratory disease and heterologous antibody response to rhinovirus. PMID- 4295283 TI - Respiratory viruses in Jamaica: a virologic and, serologic study. 1. Virus isolations and serologic studies on clinical specimens. PMID- 4295284 TI - Reovirus antibody patterns in Alaska. PMID- 4295285 TI - Vaccination of day-old chickens against infectious laryngotracheitis by conjunctival instillation. PMID- 4295286 TI - Isolation of equine rhinopneumonitis virus from an epidemic of acute respiratory disease in horses. PMID- 4295287 TI - Factors controlling the concentration of mitochondrial oxaloacetate in liver during spontaneous bovine ketosis. PMID- 4295288 TI - Phosphatidylmyoinositol monomannoside in Propionibacterium shermanii. PMID- 4295289 TI - Ribonucleotide phosphorylating enzymes (kinases) in Escherichia coli, uninfected and infected with RNA-bacteriophage f2. PMID- 4295291 TI - Optical and magnetic properties of Pseudomonas azurins. PMID- 4295290 TI - Reversible reaction of epsilon-amino groups of cytochrome c with salicylaldehyde to produce cytochrome c polymers. PMID- 4295293 TI - Analysis of a thermal equilibrium phenomenon between high-spin and low-spin states of ferrimyoglobin azide. PMID- 4295292 TI - Characterization of avian leucosis group-specific antigen from avian myeloblastosis virus. PMID- 4295294 TI - Studies on acid hydrolases. IV. Isolation and characterization of spleen exonuclease. PMID- 4295295 TI - Studies on acid hydrolases. V. Isolation and characterization of spleen nucleoside polyphosphatase. PMID- 4295296 TI - The recognition of viral RNA by mammalian ribosomes. An effect of interferon. PMID- 4295297 TI - Inhibition of the synthesis of 5-phosphoribosyl-1-pyrophosphate by 3'-deoxy adenosine and structurally related nucleoside analogs. PMID- 4295298 TI - Dihydro-5-azaorotic acid, the first specific inhibitor of dihydro-orotate dehydrogenase. PMID- 4295299 TI - The effect of low concentrations of chlorampheicol on beating rat-heart cells in tissue culture. PMID- 4295300 TI - Hepatic resection. PMID- 4295301 TI - Gas gangrene salpingo-oophoritis. PMID- 4295302 TI - Malignant melanoma of the penis: endolymphatic therapy with 131-I lipiodol. PMID- 4295304 TI - Studies on coenzyme analogs. XV. A novel phosphorylating agent, P-diphenyl-, P' Morpholino pyrophosphorochloridate. PMID- 4295303 TI - Studies on the selectivity of antitumor agents. PMID- 4295305 TI - Pattern of enzyme activity of nitrogen mustard-sensitive and resistant ascites tumors. PMID- 4295306 TI - Relation of melanoma homogenate and ascorbate solution electron paramagnetic resonance doublets. PMID- 4295307 TI - Herpes simplex virus hepatitis in mice: an electron-microscopic study. PMID- 4295308 TI - Evaluation of the complement fixation test for routine screening of amebiasis. PMID- 4295309 TI - Isolation of Herpesvirus hominis from naturally infected pet skunks. PMID- 4295310 TI - Chemical mediators of adrenaline-induced pulmonary oedema. PMID- 4295311 TI - Experimental oral hepatography in rats. PMID- 4295313 TI - Potential antiviral agents. Carbobenzoxy di- and tripeptides active against measles and herpes viruses. PMID- 4295312 TI - Measurement of human luteinizing hormone in plasma by radioimmunoassay. AB - The recent isolation of highly purified human pituitary luteinizing hormone (LH) has permitted the development of a sensitive and specific radioimmunoassay for this hormone in plasma. Results of this immunoassay system employing anti-LH serum agree closely with previous reports for the measurement of plasma LH in which immunoassays employing cross-reactive antisera to human chorionic gonadotropin were used. The immunoassay and bioassay of LH in several crude and partially purified pituitary and urinary extracts show acceptable agreement. The sensitivity of the LH immunoassay (0.2 mmug/ml) is adequate to measure LH levels in almost half of all prepuberal children and in all but a few normal adults. A small, but significant, rise in plasma LH level occurs at pubescence in both boys and girls. In women, plasma LH level varies with both age and the phase of the menstrual cycle. The mean LH concentration in nine normal women during the follicular phase (1.2 mmug/ml was found to be significantly higher than during the luteal phase (1.0 mmug/ml). At midcycle, the mean peak LH level was 10.2 mmug/ml. In a large group of normal women, the mean plasma LH concentration rose significantly at menopause to a level of 5.8 mmug/ml during the fifth decade and 10.5 mmug/ml during the seventh decade. A small, but significant, rise in plasma LH concentration also occurred in men from the third and fourth decades (0.7 mmug/ml to the seventh and eighth decades (1.7 mmug/ml). Both estrogen and testosterone suppress plasma LH levels, but marked variation in response exists. The immunoassay serves as a useful diagnostic tool in evaluating men with gonadal failure, amenorrheic women of reproductive age, and postmenopausal women suspected of hypopituitarism. From the half-time disappearance of LH-(131)I in plasma (mean 69 min) and the calculated volume of distribution (2.5-2.8 liters) it has been determined that approximately 30 mug of LH is secreted per day in men, and in women except at midcycle, at which time the release of LH is estimated to be 10-15 times this basal rate. PMID- 4295314 TI - Characterization of the simian virus 40-specific RNA in virus-yielding and transformed cells. PMID- 4295315 TI - Molecular basis of the action of interferon. PMID- 4295316 TI - Products in the initial stages of digestion of polydeoxynucleotides by pancreatic deoxyribonuclease (DNase I). PMID- 4295317 TI - Destruction of rachitogenic activity of isolated soybean protein by autoclaving as demonstrated with turkey poults. PMID- 4295318 TI - Mucoepidermoid carcinoma of a minor salivary gland: report of case. PMID- 4295319 TI - Significance of Herpesvirus hominis in respiratory secretions of man. PMID- 4295320 TI - Cholestasis of pregnancy. PMID- 4295321 TI - Cholestasis of pregnancy. PMID- 4295322 TI - [Coenzyme treatment of severe jaundice due to hepatitis (Tholen's method)]. PMID- 4295323 TI - The effect of vagotomy and subsequent carotid arterial constriction on adrenocortical secretion. PMID- 4295324 TI - Tyrosine transaminase induction in mammalian cells in tissue culture. PMID- 4295325 TI - Oligonucleotide inhibition of amino acid attachment. PMID- 4295326 TI - Translation of synthetic messenger RNA. PMID- 4295327 TI - [Concentration of the virus of myeloid leukemia of mice (Graffi et al.) from leukemia ascites]. PMID- 4295328 TI - [Contribution to the problem of placental insufficiency on the basis of the example of a diffuse chorioangioma]. PMID- 4295329 TI - [The phosphatase test in the diagnosis of pathogenicity of Staphylococcus aureus]. PMID- 4295330 TI - [Radioisotopes in experimental infection of laboratory animals with MHV 3 virus, NWS influenzal virus and with Trypanosoma brucei]. PMID- 4295331 TI - Rat intestinal microvillus membranes. Purification and biochemical characterization. AB - 1. A technique is described for the removal of subcellular contaminants from intact rat intestinal brush borders, and for the subsequent separation of a microvillus membrane fraction from a fibrillar residue. 2. Increments in invertase activity, microscopic homogeneity and low nucleic acid content indicate that the microvillus plasma membrane has been extensively purified. Multiple membrane preparations have been shown to be highly reproducible with respect to their invertase specific activity, cholesterol content and phospholipid content. Alkaline phosphatase, leucine aminopeptidase, Mg(2+)- and Ca(2+)-dependent adenosine triphosphatase and seven separate disaccharidases were shown to be predominantly confined to the membrane fraction. 3. The fibrillar fraction has been shown to contain approximately 30% of the total protein of purified brush borders, plus most of the residual nucleic acid contaminant. No evidence was found for the localization of any specific enzyme in this fraction. PMID- 4295333 TI - Investigations on vitamin D esters synthesized rats. Detection and identification. AB - 1. Vitamin D-deficient rachitic rats were given [1-(3)H]cholecalciferol by gastric intubation. After 24hr., diethyl ether extracts of liver and kidney contained 5-11% and 4.5-20% respectively of total vitamin D apparently esterified with long-chain fatty acids. 2. A two-dimensional thin-layer chromatographic technique was devised that completely separated seven synthetic vitamin D esters according to the chain length and number of double bonds in the fatty acid component. When the ;vitamin D ester' fraction from liver or kidney was co chromatographed with the standard esters, radioactivity appeared mainly in vitamin D palmitate, stearate, oleate and linoleate regions. The proportion of radioactivity in the saturated fatty acid esters was higher in kidney than in liver. 3. The same percentage of tissue vitamin D in the esterified form was found at each of two dosages of vitamin D. 4. The possible specificity of a vitamin D esterification mechanism is discussed. PMID- 4295332 TI - The chemical composition of the membranes of protoplasts and L-forms of Staphylococcus aureus. AB - Membrane fractions were prepared from Staphylococcus aureus H and 100 after dissolution of the cell walls by a lytic enzyme from Streptomyces griseus. Membranes were also prepared from the L-forms derived from the same strains. The membranes were analysed for protein, lipid, carbohydrate and RNA contents, and the fatty acid composition of the lipids was determined. A branched-chain saturated C(15) acid was the major component in all samples, and the correspondence between L-forms and parent bacteria was fairly close. The lipids were separated into non-polar-lipid, glycolipid and phospholipid fractions; the L forms contained a little more neutral lipid and much more glycolipid than the parent bacteria. In all membranes the glycolipid, which accounted for all the carbohydrate present, was a diglucosyl diglyceride. The major phospholipids of the protoplast membranes were phosphatidylglycerol and some lipoamino acids (lysine and a little alanine). On the other hand, diphosphatidylglycerol was the chief phospholipid found in L-form membranes. PMID- 4295334 TI - Investigations on vitamin D esters synthesized in rats. Turnover and sites of synthesis. AB - 1. The tissue contents of vitamin D alcohol and ester were estimated in rats 5, 10, 24, 48 and 72hr. after peroral administration of [1-(3)H]cholecalciferol. 2. The total vitamin D in liver decreased in an exponential fashion from 19% of the dose at 5hr. to 0.6% at 72hr., but the ester content remained at a relatively constant low value from 5hr., so that by 72hr. it represented 67% of the total vitamin D. Vitamin D ester in kidney increased slowly to 48hr., but by 72hr. it was only 10% of the total vitamin D. 3. The small intestine, unlike liver and kidney, contained a higher content of vitamin D ester 10hr. after administration than at later times, and it is postulated that some vitamin D was esterified during absorption from the alimentary tract. 4. Plasma contained vitamin D ester at all time intervals, and it is suggested that ester found in liver and kidney could have been transported to these sites in the blood. 5. Thoracic-duct lymph was found to transport 43% of a peroral dose of vitamin D in 12hr., of which 1.4% was esterified. The fatty acid components of the lymph vitamin D ester, determined by two-dimensional thinlayer chromatography, were mainly palmitate (31%), stearate (25%), oleate (16%) and linoleate (16%). This pattern was similar to that previously found in liver. PMID- 4295335 TI - The nature of copper in pig plasma benzylamine oxidase. PMID- 4295337 TI - Isopentenyl pyrophosphate isomerase from liver. AB - Isopentenyl pyrophosphate isomerase (EC 5.3.3.2) was purified from extracts of pig liver by ammonium sulphate fractionation and by gel filtration. After about 20-fold purification the preparations were free of phosphatase and prenyltransferase (EC 2.5.1.1), the two enzymes that could have interfered with the assays. The isomerase has a distinct pH optimum at 6.0 and is activated by Mn(2+) in preference to Mg(2+). The K(m) value for isopentenyl pyrophosphate is 4x10(-6)m. The equilibrium of the reaction favours the formation of dimethylallyl pyrophosphate. The reversibility of the isomerase reaction was demonstrated directly by the formation of isopentenyl pyrophosphate from dimethylallyl pyrophosphate. It is suggested that two prenyl isomerases might exist, one involved in the synthesis of trans- and another in the synthesis of cis polyprenyl substances. PMID- 4295336 TI - The diphosphoinositide kinase of rat brain. AB - 1. The supernatant fraction of adult rat brain contains a diphosphoinositide kinase. 2. Formation of triphosphoinositide by the enzyme in the presence of ATP and Mg(2+) ions was shown with labelled ATP or labelled diphosphoinositide. 3. The kinase was also activated by Ca(2+), Mn(2+) and Co(2+) ions, but to a smaller extent than by Mg(2+) ions. 4. In the presence of optimum Mg(2+) ion concentration the enzyme was inhibited by Ca(2+) ions. 5. Activity did not depend on thiol groups and the pH optimum was 7.3. 6. The dialysed supernatant fraction had no diglyceride kinase activity and negligible phosphatidylinositol kinase activity. 7. Triphosphoinositide phosphomonoesterase was present but showed little activity under the conditions used to assay the kinase. 8. Diphosphoinositide kinase was purified by ammonium sulphate fractionation, ethanol treatment and chromatography on Sephadex G-200. 9. This purification removed much of the triphosphoinositide phosphomonoesterase. PMID- 4295338 TI - [Methylation of inosine and uridylyl-(3'-5')inosine with dimethylsulfate]. PMID- 4295339 TI - The polymerization of adenosine 5'-diphosphate-ribose moiety of NAD by nuclear enzyme. II. Properties of the reaction product. PMID- 4295340 TI - Association of neutral deoxyribonuclease with chromatin isolated from mammalian cells. PMID- 4295341 TI - [Comparison of the carcinogenic activities of diethylnitrosamine and p dimethylaminoazobenzene on the liver]. PMID- 4295342 TI - RNA with high template activity from leukaemic myeloblasts (BAI strain A virus induced avian myeloblastosis). I. Optimal conditions for its isolation and activity in the subcellular protein-synthesizing system. PMID- 4295343 TI - RNA with high template activity from leukaemic myeloblasts (BAI strain A virus induced avian myeloblastosis). II. Sedimentation profiles of template activity and of rapid 32P labelling. PMID- 4295344 TI - [Ultrastructural studies of a murine sarcoma virus (MSV)]. PMID- 4295345 TI - Cytomegalic inclusion disease. A case report. PMID- 4295346 TI - Methods for the determination of adipose cell size in man and animals. AB - Four methods for the sizing of adipose cells in small samples of human or animal adipose tissue are compared. These methods depend on the preparation of cell suspensions by incubation of the tissue with collagenase or by prolonged fixation with osmium tetroxide and separation of the fixed cells. A Coulter electronic counter was used to count and size the suspended cells and a Zeiss particle size analyzer for the sizing of cells in photomicrographs. The use of the Coulter counter to count cells in a suspension derived from a known amount of tissue and subjected to osmium tetroxide fixation is recommended for accuracy and general applicability to adipose cells of all sizes in man and animals. PMID- 4295347 TI - Improved separation of sterols by column chromatography. AB - Some closely related sterols have been separated on columns of neutral alumina Super-Cel impregnated with silver nitrate. Most notable are the separations of some Delta(8)-sterols from their Delta(7)-isomers, separations which have been difficult, if not impossible, to achieve with other published column chromatographic methods. PMID- 4295348 TI - 6-acyl galactosyl ceramides of pig brain: structure and fatty acid composition. AB - Two glycolipids were isolated from pig brain and were shown to be the fatty acid esters of kerasin and cerebron in which the second fatty acid moiety is attached to the 6-position of the galactose. The point of attachment was shown in two ways: by permethylation and by cleavage with periodate. Methanolysis of the permethylated cerebroside esters yielded O-methyl sphingosines, methyl esters of nonhydroxy or 2-methoxy acids, and methyl 2,3,4-trimethyl galactoside. Cleavage of the cerebron ester with periodate, followed by treatment with sodium borohydride and dilute HCl, yielded ceramide plus 1-monoglyceride. The ester linked fatty acids were primarily 16:0, 18:0, and 18:1, while the amide-linked fatty acids showed the wide assortment of chain lengths typical of brain cerebrosides. The methylation step, with silver oxide and methyl iodide, yielded two derivatives with the cerebroside esters, but the structural explanation for the difference was not elucidated. The galactose in the cerebron ester was shown to exist in the beta-pyranoside form. PMID- 4295349 TI - Chromatographic separation of plasmalogenic, alkyl-acyl, and diacyl forms of ethanolamine glycerophosphatides. AB - The plasmalogenic, alkyl-acyl, and diacyl forms of ethanolamine glycerophosphatides were completely separated from each other as methylated dinitrophenyl derivatives by thin-layer chromatography on Silica Gel G. The relatively high resolving power needed was obtained by multiple unidimensional development with solvents that give very low mobility to the lipids. Under these conditions the plasmalogens moved fastest, the alkyl-acyl lipids were intermediate, and the diacyl lipids were the slowest. The presence of all these forms of lipids in the ethanolamine phosphatides of hen's eggs, ox brain, and human blood plasma could be directly demonstrated with the new method. PMID- 4295350 TI - Hydrolysis of primary and secondary esters of glycerol by pancreatic juice. AB - The relative rates of hydrolysis of the secondary ester in glycerol 1,3 benzylidene 2-oleate and in glycerol 1,3-dihexadecyl ether 2-oleate, and of the primary and secondary esters in triolein were determined. Both unaltered and selectively inactivated rat pancreatic juice were used as sources of enzyme. It was found that rat pancreatic juice contains an enzyme that can hydrolyze fatty acids esterified at the 2-position of a glyceride. This enzyme is not pancreatic lipase. It may be sterol ester hydrolase. Partial glycerides, as well as complete glycerides, can serve as substrates. Pancreatic lipase, if it can hydrolyze the 2 positioned fatty acids of a triglyceride, does so at a very slow rate. PMID- 4295351 TI - [Demonstration of a patient with an adrenal cell tumor of the ovary]. PMID- 4295352 TI - Measurement of renin in human plasma. PMID- 4295353 TI - Some cooperative studies for the future. PMID- 4295354 TI - [Contribution to the characteristics of Staphylococcus aureus]. PMID- 4295355 TI - [Enzymatic activity of the large intestinal mucosa in ulcerative colitis]. PMID- 4295356 TI - [Effects of catecholamines and angiotensin on mesenterial microcirculation]. PMID- 4295358 TI - [Interference microscopy studies on cells of different pituitary adenomas]. PMID- 4295357 TI - [Immunochemical methods in the biochemistry of proteohormones]. PMID- 4295359 TI - Increase in transmitter content of adrenergic nerves in the reproductive tract of female rabbits after oestrogen treatment. PMID- 4295360 TI - Vascular connective tissue under the influence of oestrogens. 3. Effect of oestrogens on experimental arteriosclerosis. Morphological and biochemical studies. PMID- 4295361 TI - [Evaluation of cases with iodoventriculography]. PMID- 4295362 TI - [Case of Japanese encephalitis with a relapse]. PMID- 4295363 TI - Cultivation of "difficult" viruses from patients with common colds. PMID- 4295364 TI - Necrotic cervicitis due to primary infection with the virus of herpes simplex. PMID- 4295365 TI - [Testosterone metabolism in man. Peripheral testosterone metabolism]. PMID- 4295366 TI - 2 NADH2 dehydrogenases in the basidiomycete Oudemansiella mucida. PMID- 4295367 TI - Effect of silica dusts on macrophage permeability studied with 86RbCl. PMID- 4295368 TI - Electron spin resonance studies of catalase and some of the catalase compounds. PMID- 4295369 TI - Inhibition of oxidizing enzymes by metronidazole. PMID- 4295370 TI - Prolongation of skin homograft survival by local intralymphatic radioisotope injections. PMID- 4295371 TI - Adrenocorticotropic effect in humans of a synthetic beta-1-24 corticotrophine derivative. PMID- 4295372 TI - [Tumors of the minor salivary glands]. PMID- 4295373 TI - Effects of a treatment with coenzyme A, alpha-lipoic acid, diphosphopyridine nucleotide and cocarboxylase on endogenous hepatic coma. PMID- 4295374 TI - Stereospecificity in the enzymatic conversion of delta-7-cholesten-3-beta-ol to 7 dehydrocholesterol. PMID- 4295375 TI - The conversion of L-glycerol-14-C 3-phosphate into phosphatidic acid by a solubilized preparation from rat brain. PMID- 4295376 TI - The role of arginine in the replication of herpes simplex virus. PMID- 4295377 TI - The ribonucleic acids of the infective and interfering components of vesicular stomatitis virus. PMID- 4295378 TI - Isolation of polyoma virus and Semliki Forest virus from tissue culture fluid by continuous flow zonal ultracentrifugation. PMID- 4295379 TI - Fractionation of polyoma virus DNA on hydroxyapatite: dependence on tertiary structure. PMID- 4295380 TI - On the possibility of lysophosphatide formation during Wallerian degeneration. PMID- 4295381 TI - Experimental studies on therapeutic effects of various combinations of antituberculosis drugs. II. Comparison of various regimens in treatment of experimental mouse tuberculosis infected with SM- and INH-resistant Schacht strain. PMID- 4295382 TI - [Current criteria of medical therapy of epilepsy]. PMID- 4295383 TI - [A case of Brenner tumor transformed into pseudomucinous papillary cystadenocarcinoma]. PMID- 4295384 TI - Studies on transmissible gastroenteritis in pigs. 3. Isolation of cytopathogenic viurs and its use for serological investigation. PMID- 4295385 TI - Specificity of assay of equine infectious anemia virus in horse leukocyte culture. PMID- 4295386 TI - Distribution of some dehydrogenase in the cerebellar cortex. PMID- 4295387 TI - Sialic acid of uterine muscle membrane: reappraisal of the serotonin receptor of smooth muscle. PMID- 4295388 TI - Isolation of a new toxin from cultures of Aspergillus flavus. PMID- 4295389 TI - Glucocorticoid-induced pancreatitis in children. PMID- 4295390 TI - Resection of metastases in Wilms' tumor: a report of three cases cured of pulmonary and hepatic metastases. PMID- 4295391 TI - Treatment of malignant sympathetic tumors in children: clinicopathological correlation. PMID- 4295392 TI - [ACTH and corticoid therapy]. PMID- 4295393 TI - [Cushing's syndrome with pigmentation]. PMID- 4295394 TI - [The Zollinger-Ellison syndrome. Clinical, biological, and anatomical study of 10 cases]. PMID- 4295395 TI - The de-segregation of the psychiatric patient. PMID- 4295396 TI - Studies on periodic-acid-Schiff positive substance in the thymus of mice. PMID- 4295397 TI - [The biological properties and morphology of the vesicular stomatitis virus]. PMID- 4295398 TI - [The causes of an atypical course of several virus diseases]. PMID- 4295399 TI - [The effect of hormone therapy on clinico-biochemical indices in patients with infectious hepatitis]. PMID- 4295400 TI - [Peculiarities of the clinical aspects of tumors of arterio-venous anastomoses]. PMID- 4295401 TI - [Stabilization of vitamin drugs. I. The determination of vitamin D3 in the presence of its disintegration products in aqueous solutions]. PMID- 4295402 TI - [Apropos of several apparently primary hepatic mesenchymatous tumours. Trial classification and diagnosis of spindle cell tumors of the liver]. PMID- 4295403 TI - [Cushing's disease caused by bilateral hyperplasia of the adrenals. Surgical discovery of a basophilic adenoma of the hypophysis]. PMID- 4295404 TI - [Introduction to the study of the peripheral receptors of the ortho-sympathetic system and their inhibitors]. PMID- 4295405 TI - The relationship between the state of nerve-terminal polarization and liberation of acetylcholine. PMID- 4295406 TI - Acetylcholine, bretylium and release of norepinephrine from sympathetic nerve endings. PMID- 4295407 TI - [Problems of diagnosis and treatment posed by tumors of the carotid body]. PMID- 4295408 TI - Advances in connective tissue research and their relationship to the aetiology of periodontal disease. PMID- 4295409 TI - The role of the hydrophobic bonding in P-450 and the effect of organic compounds on the conversion of P-450 to P-420. PMID- 4295410 TI - [Current knowledge on the etiology of hepatitis]. PMID- 4295411 TI - [Epidemiologic studies on intestinal protozoa in Costa Rica]. PMID- 4295412 TI - [On the sensitizing properties of quartz and sodium silicate]. PMID- 4295413 TI - [Thromboelastographic and immunological studies with fibrinogen-glycopeptide]. PMID- 4295414 TI - [Research on the problem of a cholinergic link in postganglionic sympathetic transmission]. PMID- 4295415 TI - [Double excitability of the anterior tibial. Observations on sportsmen]. PMID- 4295416 TI - [The relationship between slow synaptic potentials and excitability of the superior cervical ganglion in the rat]. PMID- 4295417 TI - Complement fixation reaction and agar gel double diffusion test in Tyzzer's disease of mice. PMID- 4295418 TI - [Inhibition of in vitro cytoxic action of silica by synthetic polymers containing the N-O group]. PMID- 4295419 TI - [Studies on the effect of cobalt chloride upon cytochrome oxidase activity in the mitochondria of the rat]. PMID- 4295420 TI - [Peripheral nerve damage in the inguinal region]. PMID- 4295421 TI - [On the finding of diatoms in drowned subjects. Experimental verifications]. PMID- 4295422 TI - [Relative content of hexoses in serum albumin non-precipitated with perchloric acid in patients with rheumatoid arthritis]. PMID- 4295423 TI - [Study of some pulmonary morphological and biochemical changes in white mice during immunization with respiratory viruses (influenzal Myxovirus, type A, and adenovirus, type 5)]. PMID- 4295424 TI - [On enzyme histochemistry of uterine glands and uterus epithelium in the birth mature sheep placenta]. PMID- 4295425 TI - Relationship of orbital sialic to endocrine exophthalmos. PMID- 4295426 TI - The heart in acute leukemia. A study of 420 autopsy cases. PMID- 4295427 TI - Rhinovirus infections in an industrial population. 3. Number and prevalence of serotypes. PMID- 4295428 TI - Live and inactivated adenovirus vaccines for the prevention of acute respiratory illness in naval recruits. PMID- 4295429 TI - Characteristics of two enteroviruses isolated from swine with diarrhea. PMID- 4295430 TI - Effects of chronic residence on size and size distribution of plaques of type A foot-and-mouth disease virus in primary calf kidney cell cultures. PMID- 4295431 TI - Primary lesions in cardiac ganglia of the pig after herpesvirus suis infection. PMID- 4295432 TI - Determnation of rat liver microsomal glucose-6-phosphatase activity: study of citrate and G-6-P inhibition. PMID- 4295433 TI - Growth of seventy-eight recurrent mammary cancers. Quantitative study. PMID- 4295434 TI - Thyroid lymphography of the dog. PMID- 4295435 TI - In vitro neoplastic transformation of hamster pineal cells by three oncogenic DNA viruses. PMID- 4295436 TI - Post-hospital treatment of the psychotic patient. PMID- 4295437 TI - Ascorbic acid depletion and corticosterone production in the avian adrenal gland. PMID- 4295438 TI - Serodifferentiation of poliovirus strains. I. Modified Wecker test on types 1 and 2 poliovirus strains. PMID- 4295439 TI - Oncogenicity of Schmidt-Ruppin strain of rous sarcoma virus in cynomolgus monkeys. PMID- 4295440 TI - Oxidation of reduced nicotinamide adenine dinucleotide by melanin. PMID- 4295441 TI - Studies of phosphorus metabolism by isolated nuclei. XI. Evidence for a multiplicity of nucleolar nucleoside diphosphatases. PMID- 4295442 TI - [Apropos of 3 cases restating the problem of multiple gliomas]. PMID- 4295443 TI - [Gliomas of the chiasm. Apropos of 9 cases]. PMID- 4295444 TI - [Serologic studies of the Moloneyn Graffi experimental leukemias]. PMID- 4295445 TI - Autoantigenic properties of proteins denatured by colloidal silicic acid. PMID- 4295446 TI - Photochemistry of biological molecules. II. Photolysis of dipeptides in the solid state. PMID- 4295447 TI - Kinetic behavior of EPR signal. I. Induction effects in intact algae. PMID- 4295448 TI - [Paralysis of the shoulder and rupture of the capsule of the shoulder joint]. PMID- 4295450 TI - [Virus infection in the runt syndrome--with special reference to polyoma virus]. PMID- 4295449 TI - The effect of chronic alcoholism on ketosteroid and hydroxycorticoid excretion. PMID- 4295451 TI - [Histological and immunofluorescent studies on the histogenesis of polyoma induced in AKR mice. I. Histological studies on various tissues at intervals after inoculation of polyoma virus into newborn AKR mice]. PMID- 4295452 TI - [Histological and immunofluorescent studies on the histogenesis of polyoma induced in AKR mice. II. The detection of viral antigen by immunofluorescent technique in various tissues at intervals after inoculation of polyoma virus into AKR newborn mice]. PMID- 4295453 TI - [Statokinesimetric study of postural regulation in man (normal and pathologic variations)]. PMID- 4295454 TI - [The delay between the last confinement and the 1st symptom in the etiology and prognosis of cancer of the uteri cervix]. PMID- 4295455 TI - [Some clinical aspects of intracardiac thrombosis]. PMID- 4295456 TI - [The polycythemia of polycystic disease of the kidney (apropos of a case)]. PMID- 4295457 TI - [Use of gonadotropins of menopausal origin in the treatment of functional insficiency of the corpus luteum]. PMID- 4295458 TI - [Rectal mucosa biopsy in the diagnosis of intestinal bilharziasis]. PMID- 4295459 TI - [Lymph node manifestations of mycosis fungoides: anatomo-pathologic study and attempted interpretation]. PMID- 4295460 TI - [Paroxysmal nocturnal hemoglobinuria evolving over 11 years parallel to severe pulmonary tuberculosis. Anatomo-clinical study]. PMID- 4295461 TI - [Unilateral pulmonary hypertransparencies. The MacLeod syndrome]. PMID- 4295462 TI - [Meckel's diverticulum of the hemorrhagic type. Arteriographic findings]. PMID- 4295463 TI - [A case of lymphoid myelofibrosis. Anatomo-clinical and critical study]. PMID- 4295465 TI - [Leonardo da Vinci, brilliant precursor]. PMID- 4295464 TI - [The anatomo-clinical syndrome of thrombosis of the terminal rt of the internal carotid artery obstructing the intersection of its branches. (Apropos of 11 cases)]. PMID- 4295467 TI - Some effects of x-irraation on circulating eosinophils in rats: a short communication. PMID- 4295466 TI - Werner's syndrome. PMID- 4295468 TI - Studies in glycogen storage disease. II. Heterogeneity in the inheritance of glycogen storage diseases. PMID- 4295469 TI - Aldosterone in clinical medicine. PMID- 4295470 TI - Microbial models of tumor metabolism. PMID- 4295471 TI - Enzyme histochemistry of ovarian tumors. PMID- 4295472 TI - [Problems on the recurrence of gliomas of the brain]. PMID- 4295473 TI - [Some elements of comparison of the hepatocarcinogenic action of 2 acetaminofluorene in rats with those of p-dimethylaminoazobenzene and diethylnitrosamine]. PMID- 4295474 TI - Relationship of the nicotinamide adenine dinucleotide glycohydrolase activity to nicotinamide adenine dinucleotide content and rate of proliferation of Ehrlich ascites tumor cells. PMID- 4295476 TI - The prenatal exposure of mice to urethan and the consequent development of tumors in various tissues. PMID- 4295475 TI - The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity. PMID- 4295477 TI - Location and characteristics of the phenylalanine transport mechanism in normal and polyoma-transformed hamster cells. PMID- 4295478 TI - Dose-response characteristics of aflatoxin B1 carcinogenesis in the rat. PMID- 4295480 TI - Immunofluorescence, interference, and complement fixation technics in the detection of the herpes-type virus in Burkitt tumor cell lines. PMID- 4295479 TI - The epidemiology of Burkitt's tumor. PMID- 4295481 TI - Formal discussion: immunologic relationships of the herpes-like EB virus of cultured Burkitt lymphoblasts. PMID- 4295482 TI - [Virus infections in the newborn infant]. PMID- 4295483 TI - [Studies on the frequency of intrauterine infections with cytmegalic virus]. PMID- 4295484 TI - [Treatment of bilharziasis]. PMID- 4295485 TI - Insulin inhibition of hormone and theophylline induced glycerol release in isolated adipocytes. PMID- 4295486 TI - Terrapene heart (TH-1), a continuous cell line from the heart of the box turtle Terrapene carolina. PMID- 4295487 TI - Fine structural cytochemical localizations of phosphatase activities of rat and guinea pig. PMID- 4295488 TI - The distribution of constituents and enzyme activities in subfractions of liver microsomes from non-starved rats. PMID- 4295489 TI - A morphologic study on the chromatin areas associated with the nucleolus. PMID- 4295490 TI - Chromosomal damage after infection with poliomyelitis virus. PMID- 4295491 TI - [On the effect of convulsive fits on the hypophyseo-suprarenal interrelations]. PMID- 4295492 TI - [Electromicroscopic-autoradiographic localisation of subcutaneously polyvinylpyridin-N-oxide in tridymite powder granuloma in rats]. PMID- 4295493 TI - Purification of interferon from chick embryonic allantoic fluids and fibroblast tissue infected with influenza virus. PMID- 4295494 TI - The inhibition of polyoma antigen synthesis and capsid formation by 5 fluorodoxyuridine. PMID- 4295495 TI - Replication of PARA (defective SV40)-adenoviruses in simian cells. PMID- 4295496 TI - Chromatographic separation of the various forms of polyoma virus DNA. PMID- 4295497 TI - Replication of Riley's plasma enzymes elevating virus in tissue culture: the importance of the cellular composition. PMID- 4295498 TI - Thermo-efficient strains of variola major virus. PMID- 4295499 TI - Increase of lactic dehydrogenase and neutralizaing antibody in plasma of chickens infected with Rous sarcoma virus. PMID- 4295500 TI - The supercoiling of papilloma virus DNA. PMID- 4295501 TI - [On the Yokkaichi-asthma]. PMID- 4295503 TI - [In vitro sensitivity of Pseudomonas aeruginosa to gentamicin]. PMID- 4295502 TI - [On the behavior of ACTH and cortisol in blood of healthy persons and patients with primary and secondary disorders in function of the adrenal cortex. II. The daily rhythm of ACTH secretion in the regulatory mechanism of the hypothalamo hypophyseal-adrenal cortex-systems]. PMID- 4295504 TI - [Dosimetric problems in intralymphatic radiotherapy]. PMID- 4295505 TI - [Intralymphatic treatment of lymph-node metastases with Lipiodol labeled with I 131, with special reference to malignant melanoma]. PMID- 4295506 TI - [Technic and observations in intralymphatic radiotherapy with lipiodol-I 131]. PMID- 4295507 TI - [On loco-regional therapy with radioisotopes]. PMID- 4295509 TI - [Central regulation of sensory messages]. PMID- 4295508 TI - [The treatment of eosinophilic and chromophobe adenomas of the pituitary gland with radioactive yttrium implants]. PMID- 4295511 TI - [On the metabolism of the genus Microsporum Gruby (1843). 2. Catabolism of horn keratin]. PMID- 4295510 TI - Enhanced severity of experimental Herpes simplex infection in mice fed a protein free diet. PMID- 4295512 TI - [Remarks on the etiology of secretory otitis media in children]. PMID- 4295513 TI - [Oncogenic viruses]. PMID- 4295514 TI - [Survey of the incidence of human iection with adenoviruses oncogenic for animals]. PMID- 4295515 TI - [Secreting teoma or luteinized stromal hyperplasia of the pregnant ovary. Virilism of the mother and female pseudohermaphrodism of the newborn child]. PMID- 4295516 TI - [Radiologic diagnosis of liver cancer--hepatic scanning and liver angiography]. PMID- 4295517 TI - [Biochemical research on the behavior of alkaline and acid phosphatase and of acid proteinase of the intestine of Triturus cristatus in the cours of metamorphosis]. PMID- 4295518 TI - [Research on the behavior of phospholipids and acid and alkaline phosphatases in the small intestine in the course of development. 3. Histochemical research on embryos and newborn of Lacerta sicula]. PMID- 4295519 TI - [Action of a sinusoidal current of 25KHz frequency on nerve excitability and conduction]. PMID- 4295520 TI - [The importance of angiotensin in clinical practice]. PMID- 4295521 TI - [Glioma and its differential diagnosis in the enzymatic histotopochemical picture]. PMID- 4295522 TI - On the ganglionic effect of trypsin. PMID- 4295523 TI - Surgical aspects of salivary gland disease. PMID- 4295524 TI - Wilms' tumor and neuroblastoma. The child under treatment. PMID- 4295525 TI - Malignant cystosarcoma phyllodes in a pre-pubertal female. PMID- 4295526 TI - Intratypic serodifferentiation of polioviruses by comparison of neutralization indices and correlation of the antigenic marker, temperature marker and monkey neurovirulence. PMID- 4295528 TI - [Clearance of inhaled particles from the lungs. Significance of stress]. PMID- 4295527 TI - Capillary, mast cell and connective tissue response to myxoviruses in the rat. PMID- 4295529 TI - Free radicals of biological interest. II. Electron spin resonance (ESR) spectra of 2537 A irradiated amino acids. PMID- 4295530 TI - Biosynthesis of chloramphenicol. II. p-Aminophenylalanine as a precursor of the p nitrophenylserinol moiety. PMID- 4295531 TI - Automated method for following the production of corticosteroids by adrenal tissue in vitro. PMID- 4295532 TI - Procedure for determination of aldosterone in human peripheral plasma by double isotope derivative assay, and its application for measurement of secretory rate and urinary excretion. PMID- 4295533 TI - Role of intraneuronal vesicles in the synthesis, storage, and release of catecholamines. PMID- 4295534 TI - Personality patterns in peripheral neuropathy. PMID- 4295535 TI - [On the status of the sympathetic innervation of the heart in experimental anaerobic poisoning]. PMID- 4295537 TI - Growth behavior of hepatomas in o-aminoazotoluene-treated mice in comparison with spontaneous hepatomas. PMID- 4295538 TI - [Purification of collagenase. 3. Production of enzymatically uniform collagenase]. PMID- 4295539 TI - The antigenicity of native and tyrosylated neutral-salt-soluble rat collagen. PMID- 4295540 TI - Enzymatic omega-oxidation. 3. Purification and properties of rubredoxin, a component of the omega-hydroxylation system of Pseudomonas oleovorans. PMID- 4295541 TI - Kinetics of binding of cyanide to sperm whale metmyoglobin. PMID- 4295542 TI - Probable murine origin of a virus (HHLV-2) recovered from leukemic mice after inoculation of human leukemic material. PMID- 4295543 TI - Preventive rehabilitation in leprosy. PMID- 4295544 TI - Clinical experience in the neurologic substance of pain. PMID- 4295545 TI - The transmission and central projection of pain. PMID- 4295546 TI - [Effct of divalent cations on the production of hyaluronidase of Clostridium perfringens type A]. PMID- 4295547 TI - [Biochemical analysis of the metabolism of 3-acetylpyridine. Isolation and identification of 6 metabolites]. PMID- 4295549 TI - [Case of mucoepidermoid cancer at the root of the tongue]. PMID- 4295548 TI - [Differential influence of the blood pressure of renin and angiotensin by means of aminopeptidase]. PMID- 4295550 TI - Antimicrobial therapy in the newborn infant. PMID- 4295552 TI - Polymyxins, colistin, bacitracin, ristocetin and vancomycin. PMID- 4295551 TI - Antimicrobial agents: pediatric dosage, routes of administration and preparation procedures for parenteral therapy. PMID- 4295553 TI - Improved dry-swab transportation for streptococcal specimens. PMID- 4295554 TI - Dissociation constants of the binary complex of homogeneous horse liver alcohol dehydrogenase and nicotiniumamide adenine dinucleotide. PMID- 4295555 TI - Inorganic pyrophosphate and the evolution of biological energy transformation. PMID- 4295556 TI - [A case of Poland's syndrome]. PMID- 4295557 TI - [Pulmonary adenomatosis or alveolar adenocarcinoma. Apropos of 4 cases]. PMID- 4295558 TI - [Disposition of the large collateral trunks of the aortic arc in African newborn infants of the Ivory Coast]. PMID- 4295559 TI - [The adipokinetic effect of ACTH in man]. PMID- 4295560 TI - [On the methods of implantation of atypical mycobacteria in the silicotic lung. (Experimental investigations)]. PMID- 4295561 TI - Trace metal composition of photosynthetic bacteria. PMID- 4295562 TI - [Lipolytic action of some hormones on infantile adipose tissue in vitro]. PMID- 4295563 TI - Sulfhydryl content of rat ascites hepatomas with different sensitivity to x-rays and nitrogen mustard N-oxide. PMID- 4295564 TI - Glucose-metabolizing enzymes in Yoshida sarcoma and its slow-growing variant subline. PMID- 4295565 TI - Effects of angiotensin and catecholamines on the mesorchium microcirculation in the rat. PMID- 4295566 TI - Effects of the administration of vitamin D2, D3, parathyroid hormone and calcium on hypocalcification of rabbit dentin and on changes in blood constituents caused by experimental rickets. PMID- 4295567 TI - [The alveolar soft tissue sarcoma (malignant Abrikosoff tumor)]. PMID- 4295568 TI - [Shock therapy with vasodilator and-or vasoconstrictor agents]. PMID- 4295569 TI - Programs for discharged patients. I. Community activities help readjustment. PMID- 4295570 TI - Programs for discharged patients. II. Halfway house and day hospital complement each other. PMID- 4295571 TI - [Biochemical observations of the alteration of DPN-diaphorase activity in the organ of Corti after noise exposure]. PMID- 4295572 TI - [Studies on carbohydrate metabolism in the liver. 3. Patterns of glucose metabolizing enzymes in the liver in patients with primary hepatoma and other tumors]. PMID- 4295573 TI - [Studies of ultrastructural changes in liver cells. II. Electron microscopic observations on experimental fatty liver]. PMID- 4295574 TI - [Apropos of the use of Panto-Viocine in the treatment of chronic tuberculous empyema]. PMID- 4295575 TI - [Tasks of medical virology]. PMID- 4295577 TI - Strange behavior of radiopaque substance. PMID- 4295576 TI - [On the biochemistry of tumor cells]. PMID- 4295578 TI - [Contribution to the definition of the maximum tolerable exposure to silicotic dusts. Experimental research in rats exposed for a brief period to minimum quantities of crystalline silica]. PMID- 4295579 TI - [The neurological manifestation of Hodgkin's disease]. PMID- 4295580 TI - Rescue of the defective murine sarcoma virus genome by radiation-induced leukemia virus from C57BL mice. PMID- 4295582 TI - SV 40-specific thymidine kinase. PMID- 4295581 TI - Sedimentation properties of mitochondrial and cytoplasmic ribosomal RNA's from Neurospora. PMID- 4295583 TI - Temperature sensitivity of polyoma virus, induction of cellular DNA synthesis, and multiplication of transformed cells at high temperature. PMID- 4295585 TI - Enzymatic joining of DNA strands, II. An enzyme-adenylate intermediate in the dpn dependent DNA ligase reaction. PMID- 4295584 TI - The enzymatic repair of DNA, II. Characterization of phage-induced sealase. PMID- 4295586 TI - Charge transfer and electronic mobility. PMID- 4295587 TI - Effect of bacteriophage infection on the sulfur-labeling of sRNA. PMID- 4295589 TI - [Action in vitro on Coxsackie virus A-9 of the intestinal factor of the normal mouse which neutralizes MHV-3 virus]. PMID- 4295588 TI - Inducers of interferon and host resistance, IV. Double-stranded replicative form RNA (MS2-Ff-RNA) from E. coli infected with MS2 coliphage. PMID- 4295590 TI - [Changes in the reactions of animal organism to higher concentrations of carbon dioxide following irradiation]. PMID- 4295591 TI - Pox in wild birds, an annotated bibliography. PMID- 4295592 TI - Mycoplasma pneumoniae and adenovirus respiratory illnesses in military and university personnel, 1959-1966. PMID- 4295593 TI - Use of the pectoralis minor muscle in augmentation mammoplasty. PMID- 4295594 TI - Cytologic diagnosis of pancreatic cancer by ductal aspiration. PMID- 4295595 TI - On the use and abuse of LSD. PMID- 4295596 TI - Hospital differences in the release of discharge ready chronic schizophrenics. PMID- 4295597 TI - Histochemical study on chromatolytic neurons. PMID- 4295598 TI - Histamine formation in normal, regenerating and malignant liver tissue of the rat. PMID- 4295599 TI - [Preparation of highly purified chromaffin granules from ox adrenal medullae]. PMID- 4295600 TI - Pelvic arteriography in the management of chorioadenoma destruens. PMID- 4295601 TI - [Excretion of total n-17-ketosteroids and their fractions during contraception with Antigest]. PMID- 4295602 TI - [Renal-vascular hypertension]. PMID- 4295603 TI - Studies of the oxygenated compound of cytochrome oxidase. PMID- 4295604 TI - Biosynthesis of the peptidoglycan of bacterial cell walls. IX. Purification and properties of glycyl transfer ribonucleic acid synthetase from Staphylococcus aureus. PMID- 4295605 TI - A new pteridine from Tetrahymena. PMID- 4295607 TI - Studies on the respiratory chain-linked reduced nicotinamide adenine dinucleotide dehydrogenase. XIV. Location of the sites of inhibition of rotenone, barbiturates, and piericidin by means of electron paramagnetic resonance spectroscopy. PMID- 4295606 TI - Studies on the respiratory chain-linked reduced nicotinamide adenine dinucleotide dehydrogenase. 13. Binding sites of rotenone, piericidin A, and amytal in the respiratory chain. PMID- 4295608 TI - Morphological investigation of human breast cancer. PMID- 4295609 TI - Immunofluorescent studies of mouse and hamster cell surface antigens induced by polyoma virus. PMID- 4295610 TI - Serologic evidence for human infection with adenovirus-associated viruses. PMID- 4295611 TI - Susceptibility of cells transformed by polyoma virus and simian virus 40 to the cytotoxic effect of the carcinogenic hydrocarbon benzo[a]pyrene. PMID- 4295612 TI - Virus-induced rhabdomyosarcoma transplantation studies in weanling BALB-c mice. PMID- 4295613 TI - Immunogenetic aspects of polyoma virus susceptibility in mice. PMID- 4295614 TI - Studies on the hamster-brain passage virus recovered from human lymphoma cultures. PMID- 4295615 TI - Uridine nucleotides in brain. PMID- 4295616 TI - Enzymes of phosphoinositide metabolism during rat brain development. PMID- 4295617 TI - Effect of glucose and fructose administration on lipid metabolism in the rat. PMID- 4295618 TI - Metabolism of diethylpropion-1-C14 hydrochloride by the human. PMID- 4295620 TI - Familial XY gonadal dysgenesis. PMID- 4295619 TI - [Nicotinacid amide as a stabilizing additive in cold storage of blood]. PMID- 4295621 TI - Acute hemorrhagic cystitis in children. Isolation of adenovirus type II. PMID- 4295622 TI - Lymphography with chlorophyll: effects on pelvic lymphadenectomy and lymph nodes. PMID- 4295623 TI - The possible etiologic relationship of virus to human leukemia. PMID- 4295624 TI - [Content of minerals in human hair of the head in various diseases]. PMID- 4295625 TI - Yields in the radiation degradation of solid carbohydrates. PMID- 4295626 TI - [On the effect of jaundice on the healing of fractures]. PMID- 4295627 TI - [Clinical observations and virus serological diagnosis of polio-like diseases. 3. Facial palsy]. PMID- 4295628 TI - [Study of focal epilepsy]. PMID- 4295629 TI - [ACTH loading test with synthetic ACTH (Ciba 30'920-Ba, Synacthen)]. PMID- 4295630 TI - [Virological examination of feces and sewage, a contribution to the practical evaluation of the poliomyelitis situation]. PMID- 4295631 TI - [Virological studies of surface waters and their results]. PMID- 4295632 TI - [The intratypical differentiation of strains of the poliovirus group (marker determination)]. PMID- 4295633 TI - [Action of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica on tissue cultures]. PMID- 4295634 TI - Estimation of gestational age. Comparison between radiological assessment and maturity scoring. PMID- 4295635 TI - The antihypertensive properties of 1-amino-4-phenyl pyridinium chloride. PMID- 4295636 TI - The assay of milk-ejecting activity in the lactating rat. PMID- 4295638 TI - [Tumors of the hypophysis]. PMID- 4295637 TI - The effect of lipolytic hormones and theophylline on heat production in brown adipose tissue in vivo. PMID- 4295639 TI - [Enzyme levels of blood and cerebrospinal fluid in cerebral arteriosclerosis without focal signs]. PMID- 4295640 TI - [A clinical and experimental study of the effect of grain dust on the respiratory organs]. PMID- 4295641 TI - [Familial Addison's disease. Adrenocortical insufficiency in 4 brothers, and several probable cases in 2 generations of the same family]. PMID- 4295642 TI - [ACTH-prednisone-penicillin in the treatment of dermatomyositis with generalized interstitial calcinosis]. PMID- 4295643 TI - An electron microscopic study of the chorioallantoic membrane following infection with Rous sarcoma virus. AB - Infection of the chick chorioallantoic membrane (CAM) with Rous sarcoma virus (RSV) has been thought by earlier workers (12, 20) to result in the transformation of the ectoderm and then the mesoderm of that organ. In the present study, CAM were infected with 10(4) PFU (pock-forming units) of RSV (Bryan high titre strain) and collected for electron microscopy at 2, 4, and 6 days postinfection. Observations of the fine structural changes in the CAM after RSV infection support a singular role of the mesenchyme in the initiation of the tumors. The ectodermal hyperplasia often associated with RSV tumors of the CAM appears to be a secondary response to the alteration of the underlying mesenchyme. These findings are discussed in detail, and an alternate course of RSV transformation of the CAM by way of the vascular bed is suggested. PMID- 4295644 TI - Formation of membrane-glycogen arrays in rat hepatoma cells. PMID- 4295645 TI - Activity of ribonuclease, acid phosphatase, and phosphodiesterase in Tetrahymena pyriformis during growth. PMID- 4295646 TI - [Cholangiography by massive perfusion]. PMID- 4295647 TI - [On the diagnosis of the brachial plexus paralysis in children]. PMID- 4295648 TI - [Scintigraphic semiological findings in tumors of the liver]. PMID- 4295649 TI - Biochemical studies of transitions from rest to activity. PMID- 4295651 TI - Studies on the serological and interfering properties of avian leucosis virus isolates from field outbreaks of disease and from three vaccines. PMID- 4295650 TI - The influence of neural activity on neural metabolism of glucose and phospholipid. PMID- 4295652 TI - [Determination of vanillyl mandelic acid in urine. Comparison of the Armstrong and Pisano methods]. PMID- 4295653 TI - [Effect of subacute administration of discrete doses of ACTH in medium grade myasthenia. (Serial electromyographic study)]. PMID- 4295654 TI - [The thyroid gland, adrenal cortex and gonads--with reference to the metabolism of thyroid hormones, the adrenal cortex and sex steroid hormones]. PMID- 4295655 TI - Rare incidence of malignant renal tumours in infancy and childhood and long-time survival. PMID- 4295656 TI - Malignant tumours of the kidney and ureter. PMID- 4295657 TI - Selective agents in cultivation of clostridia. PMID- 4295658 TI - The analysis of individual molecular species of polar lipids. PMID- 4295659 TI - Interrelationship between angiotensin and vascular alpha adrenergic receptors. PMID- 4295661 TI - [Histochemical study of enzymes in malignant melanoma of the choroid]. PMID- 4295660 TI - Comparison of iv and ia infusion of vasoactive agents on dog forelimb blood flow. PMID- 4295663 TI - The effect of photooxidation and histidine reagents on Murex trunculus haemocyanin. PMID- 4295662 TI - [The crying cat syndrome. Description of a case]. PMID- 4295664 TI - Studies on the synthesis and intracellular accumulation of protocollagen in organ culture of embryonic cartilage. PMID- 4295665 TI - Influence of pH on the conformation of angiotensin II and analog peptides. PMID- 4295666 TI - Medical staff conference. Herpes simplex meningoencephalitis. AB - These discussions are selected from the weekly staff conferences in the Department of Medicine, University of California Medical Center, San Francisco. Taken from transcriptions, they are prepared by Drs. Martin J. Cline and Hibbard E. Williams, Assistant Professors of Medicine, under the direction of Dr. Lloyd H. Smith, Jr., Professor of Medicine and Chairman of the Department of Medicine. PMID- 4295667 TI - Abnormal response of the pulmonary artery of the rabbit after high frequency sympathetic nerve stimulation. PMID- 4295668 TI - Dissociation of depolarization and ganglionic blockade induced by nicotine. PMID- 4295669 TI - The actions of benzoquinonium in the isolated cat tenuissimus muscle. PMID- 4295670 TI - Effects of 5-methylpyrazole-3-carboxylic acid (U-19425) and nicotinic acid on lipolysis in vitro and in vivo and on cyclic-3',5'-AMP phosphodiesterase. PMID- 4295671 TI - Studies on the mechanism of the hypertensive effect of prostaglandin F2-alpha. PMID- 4295672 TI - [Acute "steroid diabetes" in patients treated with glucocorticoids]. PMID- 4295673 TI - Differences in isozyme patterns of nucleic and cytoplasmic lactate dehydrogenase of rat liver cells. PMID- 4295674 TI - Analysis of antibodies against synthetic angiotensin II by the passive haemagglutination technique. PMID- 4295675 TI - Radioimmunoassay of angiotensin. PMID- 4295676 TI - Fine structure of nerve fibres in smooth muscle of the vas deferens in normal and reserpinized rats. PMID- 4295677 TI - Effect of bromide ions on junctional transmission. PMID- 4295678 TI - Adrenal-pituitary responsiveness during therapy with an oral contraceptive. PMID- 4295679 TI - Familial aldosterone deficiency: enzyme defect, diagnosis, and clinical course. PMID- 4295680 TI - Studies on the metabolism of angiotensin. PMID- 4295681 TI - [Cystic pseudotumors of the popliteal fossa in knee arthrography]. PMID- 4295682 TI - [Reovirus infections in young children]. PMID- 4295684 TI - [Susceptibility of herpes simplex virus to IDU]. PMID- 4295683 TI - Pharmacologic assistance to the failing circulation. PMID- 4295685 TI - [Experimental study of the localization of herpes simplex virus antigen in the stroma of the rabbit cornea]. PMID- 4295686 TI - [Influence of various factors on the proliferation of herpes simplex virus. II. With regard to the problem of tolerance of the herpes simplex virus for IDU]. PMID- 4295687 TI - An enzymic and fluorophotometric method for estimating urea concentrations in nanoliter specimens. PMID- 4295688 TI - The enzymic determination of galacturonic acid. PMID- 4295689 TI - The separation of nucleic acids on a modified methylated albumin-kieselguhr (MAK) column. PMID- 4295690 TI - [Parotid mixed tumor of unusual dimensions. Clinical case]. PMID- 4295691 TI - Penta-acid triglycerides of Chamaepeuce afra seed oil. PMID- 4295692 TI - [Cooperation between mitochondria and the rest of the cell for renewal of mitochondrial lipids from apple parenchyma]. PMID- 4295693 TI - [Distribution of phosphatides in the entire calf eye lens]. PMID- 4295695 TI - [Eccrine spiradenoma. Apropos of 2 cases]. PMID- 4295694 TI - [Inhibition by ATP of malate dehydrogenase, of alcohol dehydrogenase and of lactate dehydrogenase of Hevea brasiliensis latex]. PMID- 4295696 TI - Permeation kinetics of glycerol and dimethyl sulfoxide in Novikoff hepatoma ascites cells. PMID- 4295697 TI - Structure of diene-phosphonous dihalide addition products and of derived phospholenes and phospholene oxides. PMID- 4295698 TI - On the mechanism by which calcium and magnesium affect the spontaneous release of transmitter from mammalian motor nerve terminals. AB - 1. The frequency of miniature end-plate potentials (m.e.p.p.s) was recorded from neuromuscular junctions in rat diaphragm phrenic nerve preparations in vitro after preparations had soaked in solutions containing Ca in concentrations between 10(-10) and 10(-2)M and a similar range of [Mg].2. Ethylenediamine tetra acetate (EDTA) and ethyleneglycol bis (beta-aminoethyl ether) tetra-acetate (EGTA) buffers were added to prepare solutions with [Ca] and [Mg] below 10(-4)M. A computer program was used to estimate the free [Ca(2+)] in these solutions, and it was shown that the effects of Ca could be attributed to the free [Ca(2+)] in the bathing solution.3. M.e.p.p.s could still be detected without difficulty after soaking preparations for 6-8 hr in solutions containing EDTA or EGTA buffers and no added Ca. The basal frequency was unchanged upon exhibition of Ca in concentrations up to 10(-5)M and/or Mg in concentrations up to 10(-3)M.4. Ca in concentrations of and above 10(-4)M accelerated m.e.p.p. frequency from the basal level. This effect reached a maximum in [Ca] of 10 mM and raising the [Ca] above this level did not further change frequency. These effects were explained by the combination of Ca molecules with a nerve terminal receptor site. It was postulated that this combination allosterically activated the spontaneous release mechanism.5. Mg could accelerate m.e.p.p. frequency in the absence of added Ca. The interactions of Ca and Mg upon m.e.p.p. frequency indicated that Ca and Mg competed for the same sites.6. Raising the [H(+)] of the bathing medium accelerated m.e.p.p. frequency. This effect was thought to be exerted partly by combination with the same receptor sites as Ca and Mg and partly by variation of the ionization of the CaCl(2) of the bathing solution. PMID- 4295699 TI - The effects of depolarization of motor nerve terminals upon the release of transmitter by nerve impulses. AB - 1. Depolarizing currents were applied to motor nerve terminals in the rat phrenic nerve-diaphragm muscle preparation in vitro.2. During the passage of depolarizing currents the amplitude of the presynaptic nerve action potentials and of end plate potentials (e.p.p.s) was reduced in proportion to the current strength.3. The reduction in e.p.p. amplitudes was shown to be due to a reduction in the number of quanta released.4. An excess of Mg ions or the previous application of a hyperpolarizing current could prevent the reduction of e.p.p. amplitudes and quantal contents by depolarizing current.5. Depolarizing current application prevented later hyperpolarizing currents affecting e.p.p. amplitudes. PMID- 4295700 TI - Evidence for the vesicle hypothesis. AB - 1. The relationship of synaptic vesicles to the synaptic cleft was examined with the electron microscope at neuromuscular junctions in the rat diaphragm before and after bathing the preparation in a physiological salt solution for 2 hr.2. A population of vesicles was defined which appeared to ;touch' the axoplasmic membrane. These vesicles were found to be aggregated adjacent to axoplasmic densities which lay opposite the mouths of post-synaptic junctional folds.3. Soaking in the salt solution and modifications of this solution increased the proportion of folds opposed by presynaptic densities with associated vesicles.4. Soaking in solutions with 20 mM-KCl depleted both the specific vesicle population and the whole population of terminal vesicles. The effect was shown in paired experiments to be a specific effect of the 20 mM-KCl, and it was prevented by a concomitant increase of the bathing MgCl(2) concentration.5. Soaking in solutions with a raised osmotic pressure reduced the specific but not the general vesicle population.6. It is suggested that these observations support the vesicle hypothesis and that the specific vesicle population forms part of a feed-back mechanism adjusting transmitter synthesis and mobilization to the rate of release of transmitter. PMID- 4295702 TI - The effect of adrenaline on the contraction of human muscle--one mechanism whereby adrenaline increases the amplitude of physiological tremor. PMID- 4295701 TI - Disuse in the lateral geniculate nucleus of the cat. AB - 1. An attempt has been made to produce disuse in the lateral geniculate nucleus (LGN) of the cat, in the synapses between the optic nerve fibres and the principal cells of the nucleus. Evidence is produced that destruction of the visual receptor cells by iodoacetate or 1,5-di(p-aminophenoxy) pentane dihydrochloride effectively silences the optic nerve discharge and so achieves this result.2. Disuse of the LGN synapses does not cause any decrease in synaptic efficiency. The LGN response to a single stimulus to the optic nerve was not appreciably altered, and the depression which normally follows single or repeated stimuli was much reduced or absent. This increased responsiveness was unaffected by prolonged tetanization of the optic nerve during the experiment.3. Two possible explanations of the increased responsiveness are suggested: a post synaptic ;decentralization'-hypersensitivity and an increased output of transmitter per impulse. The relevance of these results to theories of learning is discussed.4. The LGN response of adult cats kept in complete darkness for periods of up to 966 days was not appreciably different from that in the normal cat and there was little or no increased responsiveness. This suggests that many retinal ganglion cells continue to discharge in total darkness for long periods. There is a possibility that disuse may develop after a long time in the dark. PMID- 4295703 TI - The detection of renin in juxtaglomerular cells. PMID- 4295704 TI - Presynaptic depolarization of dorsal column fibres by adequate stimulation. PMID- 4295705 TI - Evidence for structural changes during the action potential in nerves from the walking legs of Maia squinado. PMID- 4295706 TI - The hepatic arteriography. PMID- 4295707 TI - [Effects of angiotensin on the kidney in liver cirrhosis]. PMID- 4295708 TI - Ultrastructural evaluation of the canine hypothalamic-neurohypophysial system in diabetes insipidus associated with pituitary neoplasms. PMID- 4295709 TI - The lesions of porcine adenoviral infection in germfree and pathogen-free pigs. PMID- 4295711 TI - [Anaerobic spirogenic bacteria in powdered milk]. PMID- 4295710 TI - [Pneumoencephalographic and neurological objectification of effect of radiotherapy in a child with spongioblastoma of the pons]. PMID- 4295712 TI - An autoradiographic study of satellite cells in autonomic ganglia. PMID- 4295713 TI - [Further studies on the cellular storage of carboxymethylcellulose and polyphloretin phosphate]. PMID- 4295714 TI - [Contribution to the knowledge of the structure and metabolism of the heart valves of cattle]. PMID- 4295715 TI - [Salivary type mixed tumors of the skin (chondroid syringoma). Presentation of 2 cases with facial localization]. PMID- 4295716 TI - [Rosenthal's "fibers" and spongioblastoma of the central nervous system. II. Electron microscopic studies on the significance of Rosenthal's "fibers"]. PMID- 4295717 TI - [Secretion of estrone and estradiol by the embryonic ovary of te duck, cultivated in vitro]. PMID- 4295719 TI - [Experimental infection of the testis with rhinotracheitis (IBR) virus]. PMID- 4295718 TI - [Extracellular space and turnover rates of phosphorylated fractions and free nucleotides of uterine muscle. Effects of adrenaline]. PMID- 4295720 TI - [Diphosphopyridin nucleotide in the urine in progressive muscular dystrophy]. PMID- 4295721 TI - Serological responses of horses immunized with live attenuated African horse sickness vaccine. PMID- 4295722 TI - Comparative study on neutralization tests in Japanese encephalitis. PMID- 4295723 TI - "Pagetoid" change in the bronchial mucosa. PMID- 4295724 TI - [Considerations on ovarian tumors with endocrine activity. On the subject of neoplasms of the female genital system]. PMID- 4295725 TI - [The constituents of plankton in the principal bodies of water of the province of Ferrara]. PMID- 4295726 TI - [Varicella and corticoids (presentation of a fatal case and review of the literature)]. PMID- 4295727 TI - Primary hepatoma deoxyribonucleic acid from the Bantu. PMID- 4295728 TI - Management of patients with Wilm's tumor. PMID- 4295729 TI - Mixed tumors in ectopic sites. PMID- 4295730 TI - Hernia repair: an out-patient procedure. PMID- 4295731 TI - Comparison of clinical observations on patients infected with Entamoeba histolytica, with serological titres of their sera and virulence of their amoebae to rats. PMID- 4295732 TI - [Abdominal form of hepatolenticular degeneration as a result of epidemic hepatitis]. PMID- 4295733 TI - [The use of ACTH and steroid hormones in the combined treatment of neurities of the facial nerve]. PMID- 4295734 TI - [The role of the common herpes virus (herpes simplex) in neurologic infections]. PMID- 4295735 TI - [Nevobasiloma]. PMID- 4295736 TI - Metastasis to the chamber angle from mucoid breast carcinoma. PMID- 4295738 TI - Serum angiotensinase activity in cirrhosis. PMID- 4295737 TI - Effect of postmortem interval on histochemical reactions of the myocardium. PMID- 4295739 TI - Antihypertensive effect of an isolated phospholipid. PMID- 4295740 TI - [Angiographic study of a case of tympano-jugular paraganglioma]. PMID- 4295741 TI - [Nucleic acids in senile keratosis, Bowen's disease and Paget's disease]. PMID- 4295742 TI - [On amino acid modifications after high dose irradiation: dipole diffusion of the ESR lines for high radical concentrations]. PMID- 4295743 TI - Sniffly schoolchildren. PMID- 4295744 TI - Prolonged peritoneal dialysis in patients awaiting renal transplantation. PMID- 4295745 TI - [Fibroadenoma intracanaliculare phyllodes mammae (cystosarcoma phyllodes)]. PMID- 4295746 TI - Symposium on equine bone and joint diseases. Age and species differences in bone. PMID- 4295748 TI - Studies with puromycin on the mechanism of negative feedback inhibition of ACTH secretion by glucocorticoids. PMID- 4295747 TI - [Therapy of the nephrotic syndrome]. PMID- 4295749 TI - [Nevus syringocystadenosus papilliferus in linear arrangement]. PMID- 4295750 TI - Development in hamsters of antibodies against surface antigens present in cells transformed by papovavirus SV40. PMID- 4295751 TI - Auriculotemporal syndrome secondary to vertical sliding osteotomy of the mandibular rami: report of case. PMID- 4295752 TI - Wilms' tumor in bone marrow aspirate. PMID- 4295753 TI - The origin of acetylcholine released from guinea-pig intestine and longitudinal muscle strips. AB - 1. Strips of longitudinal muscle can be obtained from guinea-pig ileum either retaining or free from Auerbach's plexus.2. The denervated strip is unresponsive to electrical stimulation by brief shocks, whether given singly or in trains; it also fails to respond to nicotine or dimethylphenylpiperazinium iodide (DMPP), and eserine causes no spasm.3. Denervated strips neither contain detectable acetylcholine (< 0.4 ng/mg), nor release it spontaneously (< 5 pg/mg/min) or in response to stimulation (< 31 pg/mg/min). The acetylcholine metabolism of the innervated strip is therefore that of the adherent Auerbach's plexus. Innervated strips had a mean acetylcholine content of 28 ng/mg, a mean resting output of 94 pg/mg/min and an output in response to stimulation at 10 c/s of 700-1200 pg/mg/min.4. By comparing the responses of innervated and denervated strips it was concluded that arecoline, methylfurmethide, alpha,beta-ethylal-gamma-tri methylammonium propanediol iodide (2268 F), muscarine, histamine, tremorine, oxytocin, and substance P, like acetylcholine, act primarily on the smooth muscle directly; and that angiotensin, barium, potassium, m-bromophenyl choline ether and 5-hydroxytryptamine have a progressively increasing proportionate effect on the nerve plexus. Nicotine and DMPP were inactive in the absence of the plexus.5. The longitudinal muscle with its accompanying plexus contains about one quarter of the acetylcholine of the whole ileum, and is responsible for about one fifth of the output to electrical stimulation.6. The volley output of acetylcholine by the innervated strip declines sharply as rate of stimulation increases. Output of acetylcholine was reduced by morphine and by cocaine, particularly when resting or when stimulated at low rates.7. Acetylcholine output by whole ileum from guinea-pig declines in the absence of glucose, but is insulin-independent. Output by strips of ileum from rats made diabetic with alloxan was similar to that from normal rats.8. The similarity in properties of acetylcholine output from innervated strips, where it must come from nervous tissue, to that from whole ileum, and the insulin-independence of output from whole ileum suggest that the whole of the acetylcholine output of intestine is nervous in origin.9. Comparison of the acetylcholine metabolism of the innervated strip with that of the superior cervical ganglion suggests that the typical features of the former (high resting output, high volley output at low rates, low minute output at high rates of stimulation, and sensitivity to morphine) may be linked with the absence of specialized neuro-effector junctions and represent a relatively primitive transmission process. PMID- 4295755 TI - Reticulospinal inhibition of interneurones. AB - 1. The effect of electrical stimulation of the brain stem on interneurones in the dorsal horn and intermediary region has been investigated in decerebrate cats after partial transection of the spinal cord.2. Stimuli that effectively depress reflex transmission without giving a primary afferent depolarization inhibit the discharge evoked from the flexor reflex afferents in interneurones.3. Brain stem stimulation did not give post-synaptic potentials in the great majority of interneurones but effectively depressed the excitatory post-synaptic potentials (EPSPs) and inhibitory post-synaptic potentials (IPSPs) evoked from the flexor reflex afferents in these interneurones.4. IPSPs were, however, evoked in five of seventy-eight intracellularly recorded interneurones. These five interneurones were monosynaptically activated from primary afferents.5. It is tentatively postulated that a dorsal reticulospinal system inhibits reflex transmission by giving post-synaptic inhibition in first order interneurones. The results are also discussed in relation to effects on interneurones from other descending pathways. PMID- 4295754 TI - Reticulospinal inhibition of transmission in reflex pathways. AB - 1. The effect of electrical stimulation of the brain stem on reflex transmission has been investigated in decerebrate cats after partial transection of the spinal cord.2. Brain stem stimuli that do not evoke inhibitory post-synaptic potentials (IPSPs) in motoneurones or primary afferent depolarization may still effectively depress the excitatory and inhibitory synaptic actions evoked from the flexor reflex afferents (FRA) and from Ib afferents. There is no effect on post-synaptic potentials from Ia afferents or on Renshaw IPSPs. The depression is not associated with any measurable change in conductance over the motoneuronal membrane.3. There is also inhibition from the brain stem of transmission from the FRA (but not from Ia and Ib afferents) to primary afferent terminals and to ascending spinal pathways.4. It is concluded that this inhibition from the brain stem is exerted at an interneuronal level in spinal reflex paths.5. The inhibitory action is evoked from the region of Magoun's inhibitory centres in the brain stem and is mediated by axons with a conduction velocity of at least 20 m/sec. The axons are distributed in the dorsal part of the lateral funicle.6. The pathway mediating the inhibition from the brain stem is named the dorsal reticulospinal system. Its possible role in maintaining the decerebrate control of reflexes is discussed and related to the problem of a selective control of some paths from a primary afferent system. PMID- 4295756 TI - The reflex regulation of arterial pressure during sleep in man. PMID- 4295758 TI - Pituitary adrenocortical function in multiple sclerosis. PMID- 4295757 TI - Vasomotor responses in the hind limbs of foetal and new-born lambs to asphyxia and aortic chemoreceptor stimulation. AB - 1. Hind limb blood flow was measured in lambs of from 91 days gestation (delivered by Caesarean section) to 1 month after birth (term is about 147 days), under chloralose anaesthesia. Vascular resistance/100 g wet wt. increased progressively with age. There was reflex femoral vascular tone from the earliest age studied, as shown by vasodilatation on cutting the sciatic nerve.2. On asphyxia by cord occlusion reflex femoral vasoconstriction began earlier and was somewhat greater in older foetal lambs. At all ages, and after denervation of the hind limb, there was vasodilatation after local ischaemia, and a vasoconstriction of delayed onset during asphyxia attributed to release of noradrenaline into the circulation. The vasoconstrictor effect of noradrenaline in immature lambs was at least as great as at term or in the new-born.3. Injections of minimal effective doses of cyanide were used to localize possible chemoreceptor sites in foetal lambs. Injection into the left atrium caused a rise of arterial pressure, femoral vasoconstriction and a complex change in heart rate (usually bradycardia) but rarely any respiratory movement. After atropine, cyanide caused a large tachycardia. All responses were much reduced or abolished by cervical vagotomy.4. Injection of the same doses of cyanide into a jugular vein, the right ventricle, pulmonary or common carotid arteries of foetal lambs caused negligible cardiovascular or respiratory effects, whereas injection into the carotids of new born lambs caused a profound hyperpnoea.5. It is concluded that the aortic chemoreceptors are active in the foetus, are supplied from the left heart, and that they probably represent the primary defence in blood gas homeostasis by their effects on the circulation. PMID- 4295759 TI - Control of ventricular fibrillation during induced hypothermia in cats after blocking the adrenergic neurons with bretylium. PMID- 4295760 TI - Angiotensin and tyramine tachyphlylaxis in isolated rat aorta. PMID- 4295761 TI - Noradrenaline and sympathetic transmission. PMID- 4295762 TI - [On a charge-transfer complex of lysozyme]. PMID- 4295763 TI - Isolation of isopimpinellin from the fruits of Ammi majus L. natural coumarins. IV. PMID- 4295766 TI - [Duodenal dyskinesia and digestive migraine]. PMID- 4295765 TI - [Evaluation of pituitary-adrenal reserve in patients with systemic lupus erythematosus treated with steroids]. PMID- 4295764 TI - [Enzymatic degradation of cytotoxic purine derivatives]. PMID- 4295767 TI - [Action of Carbocromene in acute and chronic coronary insufficiency]. PMID- 4295768 TI - The family of the surgical patient. PMID- 4295769 TI - [Stokvis reaction (pentdyopent reaction)]. PMID- 4295770 TI - [Epidemiological studies on adenovirus infections]. PMID- 4295771 TI - Comparison of the traumatic deciduoma with the normal decidual reaction in mice. PMID- 4295772 TI - The effect of reserpine implantation in subcortical structures on ACTH secretion and on locomotor activity. PMID- 4295773 TI - [Production of silicosis through inhalation of amorphic arc silicic acid]. PMID- 4295774 TI - [Incidence and distribution of antibodies against causal agents of respiratory infections in the serum of cattle in Italy. II. Serum neutralization of infectious rhinotracheitis virus]. PMID- 4295775 TI - [Incidence and distribution of antibodies against the causal agents of respiratory infections in the serum of cattle in Italy. 3. Hemagglutination inhibition by "Myxovirus parainfluenzae 3"]. PMID- 4295776 TI - Clearing-factor lipase in adipose tissue. Studies with puromycin and actinomycin. AB - 1. When adipose tissue from starved rats is incubated in a medium containing glucose, insulin, heparin and actinomycin (5mug./ml.) the total clearing-factor lipase activity of the system increases at least tenfold over a period of 9hr. In the absence of actinomycin, enzyme activity also increases, but to a lesser extent and for only about 3hr. Some enzyme activity appears in the incubation medium in both the presence and the absence of actinomycin. 2. When the glucose and insulin of the incubation medium are replaced by pyruvate and heparin is omitted, an increase in the total clearing-factor lipase activity in the presence of actinomycin still occurs, but only after a lag of several hours. When only heparin is omitted from the medium, the rise in enzyme activity begins immediately, but there is a shoulder in the time-course curve after a few hours. In the absence of heparin, little enzyme activity appears in the incubation medium. 3. The increases in enzyme activity in the presence of actinomycin are prevented if puromycin (0.5mg./ml.) is present in the incubation medium. 4. Catecholamines and corticotrophin inhibit the increase in enzyme activity caused by actinomycin. 5. The clearing-factor lipase activity of adipose tissue from fed animals declines with a half-life of between 1 and 1.5hr. when the tissue is incubated in the presence of puromycin. The clearing-factor lipase activity of adipose tissue from starved animals is stable under similar circumstances, as is the raised activity found after such tissue has been incubated in the presence of actinomycin. 6. Clearing-factor lipase extracted from adipose tissue of fed animals is less stable in solution than that extracted from the tissue of starved animals after this has been incubated in the presence of actinomycin. PMID- 4295777 TI - The kinetics of the reversible inhibition of heart lactate dehydrogenase through the formation of the enzyme-oxidized nicotinamide-adenine dinucleotide-pyruvate compounds. AB - The inhibition of lactate dehydrogenase at high pyruvate concentration was studied in three ways. First, a rapid decrease in the rate of the enzyme reaction was observed; secondly, the rate of formation of a pyruvate-NAD(+) compound was followed by the change in E(325); thirdly, the rate of quenching of the protein fluorescence was measured. The data obtained at pH6.0 at different temperatures and ionic strengths as functions of pyruvate, NAD(+) and enzyme concentrations show that the extent of inhibition can be correlated with the reversible formation of a compound between pyruvate and enzyme-bound NAD(+). It is suggested that the detailed kinetic analysis of the formation of this abortive ternary compound will give pertinent information about properties of the enzyme-NAD(+) compound involved in the normal catalytic process. PMID- 4295778 TI - Chloroplast and cytoplasmic low-molecular-weight ribonucleic acid components of the leaf of Vicia faba L. AB - 1. A method for the extraction of plant nucleic acids and their separation on methylated-serum-albumin-kieselguhr columns is described. It is demonstrated that the characteristics of the elution profiles of material from the same source are consistently reproducible. 2. Major dissimilarities were found in the elution profiles of nucleic acids from root and from leaves of Vicia faba L. These dissimilarities were confirmed by polyacrylamide-gel electrophoresis. 3. Four distinct types of low-molecular-weight RNA were demonstrated to be present in leaves, clearly distinguished by their behaviour when chromatographed on methylated-serum-albumin-kieselguhr columns. (a) Both cytoplasmic and chloroplast ribosomes contained a low-molecular-weight RNA, and these components were distinct from each other. (b) The chloroplast possessed a unique ;soluble' RNA (i.e. RNA that is not precipitated by centrifugal forces that sediment ribosomes) which was not present in the rest of the cell. (c) A soluble component, probably transfer RNA, was found in both the chloroplasts and in the cytoplasm. 4. The components distinguishable by methylated-serum-albumin-kieselguhr column chromatography could not be distinguished by sucrose-density-gradient centrifugation. PMID- 4295779 TI - [Antigenicity of polynucleotide complexes]. PMID- 4295780 TI - Properties of a ribonucleate 2'-nucleotidohydrolase in a mouse lymphosarcoma. PMID- 4295781 TI - Mitochondrial DNA. I. Preparation and properties of mitochondrial DNA from chick liver. PMID- 4295782 TI - Adenyl cyclase of Brevibacterium liquefaciens. PMID- 4295783 TI - A dual-label technique for comparing the rates of synthesis of nucleic acid fractions separated by methylated albumin-kieselguhr chromatography from cells in different states of activity. PMID- 4295784 TI - Stability of radiation-induced organic free radicals. Decay by heat. AB - The rate of free radical decay was measured at various temperatures using electron paramagnetic resonance spectroscopy. Rate constants determined from first-order decay kinetics were used to determine the activation energy for the process of free radical decay. The similarity between the temperature dependence of free radical decay by heat and that of electrical conductivity has led us to consider the possibility that the two processes may be related. Mechanisms by which a population of electron-hole conducting states may lead to free radical decay are outlined and experimental data relating to these mechanisms are discussed. PMID- 4295786 TI - [Studies on reserve function of the adrenal cortex in children with total urinary 17-hydroxycorticosteroids as an indicator. 1. Its urinary excretion by successive loading of ACTH in healthy children]. PMID- 4295785 TI - [Effects of adrenal cortex hormones on iodinated amino acid fraction in the rat thyroid gland]. PMID- 4295787 TI - [Studies on adrenal cortex reserve function of the adrenal cortex in children with total urinary 17-hydrooxycorticosteroids as an indicator. 2. Its urinary excretion by successive loading of ACTH in various pediatric diseases]. PMID- 4295788 TI - Studies on Brown FK. II. Degradative changes undergone in vitro and in vivo. PMID- 4295789 TI - [Phosphatases in semen]. PMID- 4295790 TI - [Cortisone therapy of rheumatism]. PMID- 4295791 TI - Enzymatic reactions at termini of DNA. PMID- 4295792 TI - Radiological notes. Bilateral Wilms' tumors. PMID- 4295793 TI - Presynaptic effect of oxygen on neuromuscular transmission in the frog. PMID- 4295794 TI - Histochemical studies of the formazan reaction. I. A theoretical review of some of the factors that can affect the conversion of periodate-oxidized mucosubstances into formazans. PMID- 4295795 TI - Histochemical studies of the formazan reaction. II. The conversion of periodate reactive mucosubstances into diphenyl and phenyl-4'-diazo-3, 3'-dimethoxybiphenyl formazans and related derivatives. PMID- 4295796 TI - An analogue device for computing variance of time intervals as a function of the mean. PMID- 4295797 TI - [Hysteriosis in cross circulation]. PMID- 4295798 TI - Elements of neurography. PMID- 4295799 TI - [Orbital mixed tumor with a starting point in the lacrimal gland]. PMID- 4295800 TI - [To the problem of the effect of hormone therapy (ACTH, prednisolone) on the protein composition of the blood]. PMID- 4295801 TI - [Certain problems of the clinical picture and pathological anatomy of the insulomas]. PMID- 4295802 TI - [Function of the adrenal cortex in women with gastro-duodenal ulcer]. PMID- 4295803 TI - [Motor disorder in focal damage to the mediobasal portion of the temporal lobe]. PMID- 4295804 TI - A light and electron microscopy study of an unusual widespread nuclear inclusion body disease. A possible residuum of an old herpesvirus infection. PMID- 4295805 TI - Peripheral nerve lesion in spongy degeneration of the central nervous system. PMID- 4295806 TI - Simultaneous generalized cytomegalic inclusion disease and Pneumocystis carinii pneumonia. A case of a 2 year 5 month old girl. PMID- 4295807 TI - Marine bacteria and their possible relation to the virus inactivation capacity of sea water. PMID- 4295808 TI - The effect of angiotensin II infusion, renal hypertension and nephrectomy on salt appetite of sodium-deficient sheep. PMID- 4295809 TI - The catecholamines in the central artery of the rabbit ear. PMID- 4295811 TI - Studies on (Na+-K+)-activated ATPase. XIX. Occurrence and properties of a (Na+ K+)-activated ATPase in Escherichia coli. PMID- 4295810 TI - Characterization of succinate semialdehyde dehydrogenase from rat brain. PMID- 4295812 TI - Purification and properties of dichlorophenol-stimulated NADH oxidase from rat uterus. PMID- 4295813 TI - The effect of some metabolites on glucose-6-phosphate dehydrogenase activity in loach embryos. PMID- 4295814 TI - Inorganic pyrophosphatase activity of human placental alkaline phosphatase. PMID- 4295815 TI - Activation and stability of lysosomal acid phosphohydrolase. PMID- 4295816 TI - Desensitization of kidney fructose-1,6-diphosphatase by acetic anhydride. PMID- 4295817 TI - Activation by electrolytes and polylysine of poly(A) synthesis by Clostridium perfringens polynucleotide phosphorylase. PMID- 4295818 TI - [Influence of prednisolone on myocarditis in the course of experimental infection with MHV-3 virus: histological, electrocardiographic and biochemical studies]. PMID- 4295819 TI - [Influence of digoxin on respiratory chromoproteins of the myocardium (preliminary note)]. PMID- 4295820 TI - The effects of prostaglandins E1 and E2 on the smooth muscle of the dog spleen and on its responses to catecholamines, angiotensin and nerve stimulation. PMID- 4295821 TI - The effects that patients have on their families in a community care and a control psychiatric service--a two year follow-up. PMID- 4295822 TI - [Position of the pharyngeal hypophysis in the hypothalamus-adenohypophysis system]. PMID- 4295823 TI - Effect of corticotropin (ACTH) on tissue mast cell of rat. PMID- 4295824 TI - Arrhenoblastoma of the ovary: a review of the literature and report of two cases. PMID- 4295825 TI - [Subacute mumpsthyroiditis and its management]. PMID- 4295826 TI - [Polyneuritis during the course of chronic uremia. Follow-up after renal transplantation (10 personal cases)]. PMID- 4295827 TI - Mouse cellular DNA enclosed in polyoma viral capsids (pseudovirions). PMID- 4295828 TI - Production of SV40 virus in heterokaryons of transformed and susceptible cells. PMID- 4295829 TI - Isolation of adenovirus-associated viruses from man. PMID- 4295830 TI - An experimental model for internal denaturation of linear DNA molecules. PMID- 4295831 TI - The keratosulfate-like mucopolysaccharide of chick allantoic fluid. PMID- 4295832 TI - Flavoproteins of mitochondrial fatty acid oxidation. PMID- 4295833 TI - Adenosine 3',5'-monophosphate in rat uterus: acute elevation by estrogen. PMID- 4295834 TI - Inducers of interferon and host resistance. 3. Double-stranded RNA from reovirus type 3 virions (reo 3-RNA). PMID- 4295835 TI - [Monoamines and the central nervous system. I. Photomyoclonic threshold and serotonin]. PMID- 4295836 TI - Tetanus. PMID- 4295837 TI - [Neurohumoral mechanisms of radiation injuries of the dentomaxillary system]. PMID- 4295838 TI - Bile acid chemistry. 3. Stepwise side-chain shortening by way of sodium per iodate oxidation of alpha-hydroxy bile acids into corresponding aldehydes. PMID- 4295839 TI - [Protective media in drying type A foot-and-mouth disease virus]. PMID- 4295840 TI - Congenital hypophosphatasia in a Nigerian neonate. PMID- 4295841 TI - Irrigation of anterior chamber with neomycin-polymyxin solution in intraocular surgery. PMID- 4295842 TI - Renal adenomas induced by dimethylnitrosamine. Enzyme histochemistry in the rat. PMID- 4295843 TI - [Demonstration of 3-indolyl-acetaldehyde during tryptophan metabolism in Rhizobium]. PMID- 4295844 TI - [Paraneoplastic Cushing's syndrome in primary liver carcinoma]. PMID- 4295845 TI - Lysosomal enzymes associated with vitreous hyalocyte granules. 1. Intracellular distribution patterns of enzymes. PMID- 4295846 TI - Further investigations by electron microscopy of herpes simplex virus in the corneal stroma of rabbits with experimental keratitis. PMID- 4295847 TI - [Animal experiments on absorption viremia per vaginam with poliomyelitis virus]. PMID- 4295848 TI - Antigenic relationship of the gram-negative organism causing canine abortion to smooth and rough brucellae. AB - The use of whole-cell antigens in agglutination and agglutinin-absorption tests showed that the organism causing abortion in dogs is similar to rough Brucella abortus, B. melitensis, and B. ovis, but different from smooth Brucella cultures. Water-soluble antigens obtained by ultrasonic treatment and examined by immuno electrophoresis and gel diffusion show extensive cross-reactions within the genus Brucella, but little or no cross-reaction with similar antigens from other gram negative genera in the family Brucellaceae. The dog organism showed near identity with rough and smooth Brucella cultures on the basis of immuno-gel diffusion tests with water-soluble antigens, but it lacked the lipopolysaccharide-endotoxin associated with the agglutinogen of smooth brucellae. These findings support the proposal of Carmichael and Bruner for the designation of a new species, "Brucella canis." PMID- 4295849 TI - Effects of electrocoagulation of the foetal lamb hypophysis on growth and development. PMID- 4295850 TI - Changes in plasma cortisol induced by dexamphetamine and chlordiazepoxide given alone and in combination in man. PMID- 4295851 TI - [The placenta--the chorionic endocrinium and chorionic tumors]. PMID- 4295853 TI - [The enigma of La Mauresse]. PMID- 4295852 TI - Corticosteroids in the treatment of chronic asthma. PMID- 4295854 TI - Restoration of the respiration inhibited by rotenone following the addition of glucose to Ehrlich ascites tumor cells. I. Effects of metabolic inhibitors. PMID- 4295855 TI - [Preparation of neuroglia for microelectrophoresis of the ribonucleic acid bases]. PMID- 4295856 TI - On the role of ubiquinone in mitochondria. II. Redox reactions of ubiquinone under the control of oxidative phosphorylation. PMID- 4295857 TI - [Preparation of radioactively tagged pyridoxal-5'-phosphate]. PMID- 4295859 TI - A project to relieve overcrowding. PMID- 4295858 TI - The discharged chronic patient's utilization of health resources: a preliminary report. PMID- 4295860 TI - [A micromethod for rapid transesterificatio n of lipids on thin layer plates with sodium methylate for gas chromatographic analysis of fatty acid methyl ester]. PMID- 4295861 TI - The quantitative determination of some mitragyna oxindole alkaloids after separation by thin-layer chromatograppy. I. Ultraviolet spectrophotometry. PMID- 4295862 TI - A chromatographic method for the quantitative determination of cholesterol 14 methylhexadecanoate (carcinolipin) in biological materials. PMID- 4295863 TI - [The chromatography of proteins and nucleic acids on paper and thin layers]. PMID- 4295864 TI - Thin-layer and column chromatography of erythromycins and some degradation products. PMID- 4295865 TI - A rapid preparative thin-layer chromatographic technique for serum lipids. PMID- 4295866 TI - Biosynthesis of beta-glucuronides of retinol and of retinoic acid in vivo and in vitro. AB - After the intraportal injection of retinol-6,7-(14)C to rats, the O-ether derivative of retinol, retinyl -glucosiduronate, appears in the bile. Both retinoyl -glucuronide and retinyl -glucosiduronate are also synthesized in vitro when washed rat liver microsomes are incubated with uridine diphosphoglucuronic acid (UDPGA) and either retinoic acid or retinol, respectively. The synthesis of retinoyl -glucuronide was also demonstrated in microsomes of the kidney and in particulate fractions of the intestinal mucosa. The glucuronides were characterized by their UV absorption spectra, by their quenching of UV light or fluorescence under it, by their thin-layer chromatographic behavior in two solvent systems, and by the identification of products released during their hydrolysis by -glucuronidase. With retinoic acid as the substrate, the UDP glucuronyl transferase of rat liver microsomes had a pH optimum of 7.0, a temperature optimum of 38 degrees C, and a marked dependence on the concentrations of both retinoic acid and UDPGA, but was unaffected by a number of possible inhibitors, protective agents, and competitive substrates. The conversion of retinal to retinoic acid and the synthesis of retinoyl -glucuronide from retinoic acid could not be detected in whole homogenates, cell fractions, or outer segments of the bovine retina. PMID- 4295867 TI - Characterization of vitamin K from bovine liver. AB - Concentrated fractions of vitamin K from bovine liver were purified by thin-layer chromatography and fractions were analyzed by UV spectroscopy and mass spectrometry. The chromatographic behavior of the purified vitamins was compared with that of known compounds on thin layers of silica gel, either untreated or impregnated with silver nitrate or paraffin. The principal forms of vitamin K recovered from bovine liver were highly lipophilic. Two fractions were obtained which collectively gave identifiable mass spectra of menaquinone-10, menaquinone 11, and menaquinone-12. PMID- 4295868 TI - Mass spectrometry of derivatives of cyclopropene fatty acids. AB - Diketo fatty acids prepared by ozonization of cyclopropene fatty acids have been separated and purified by chromatographic techniques. Mass spectra of esters of these compounds and of methanethiol adducts of cyclopropene acid esters are reported and interpreted. Location of the ring from examination of mass spectra of these derivatives appears to be a straightforward matter. PMID- 4295869 TI - Analysis of fatty acids of human red cells without lipid extraction. AB - Exposure of human red cells to 2 N HCl for 18-20 hr at 110 degrees C appears to release the total fatty acid, which can then be esterified for GLC analysis. This technique is simpler and may be more reliable than the conventional methods that depend on lipid extraction of the red cells. PMID- 4295870 TI - Crisis: paradigms of intervention. PMID- 4295871 TI - The therapeutic milieu of the art department at the Allan Memorial Institute. PMID- 4295872 TI - Some criteria of clinical change and measurement. PMID- 4295873 TI - Remotivation for return to community life. PMID- 4295874 TI - Nursing care plans: survey of status and opinions about current usage. PMID- 4295875 TI - David HP: Auxiliary personnel in nursing--World Health Organization. PMID- 4295877 TI - Psychiatric drugs & trends. Look-alike and sound-alike drugs. PMID- 4295876 TI - Speaking out. On: is nursing tuned-in to the turned-on generation? PMID- 4295878 TI - [Tumors of arterio-venous anastomoses (glomus type)]. PMID- 4295879 TI - [Diagnostic errors in Barre-Masson tumors]. PMID- 4295880 TI - MNA economic security program; past, present and future. PMID- 4295881 TI - Cerebral tumors in infancy. 66 clinicoanatomical case studies. PMID- 4295882 TI - Multiple hemangiomata with thrombopenia. An unusual case with comments on steroid therapy. PMID- 4295883 TI - Panel discussion on ulcerative colitis. PMID- 4295884 TI - Clinicopathological conference. PMID- 4295885 TI - Repair of ptosis using human sclera. PMID- 4295886 TI - [Specific vaccine therapy and recurrent herpetic keratitis]. PMID- 4295887 TI - Inflammatory changes in newly formed vessels of carrageenin-induced granulomas after systemic 5-hydroxytryptamine, bradykinin, kallikrein, or lysolecithin. PMID- 4295888 TI - Isolation of cytomegalovirus and clinical manifestations of infection at different ages. PMID- 4295889 TI - The metabolism of isolated pneumocytes from rabbit lung. PMID- 4295890 TI - Some properties of cytoplasmic RNA fractions of the mouse Ehrlich ascites carcinoma. PMID- 4295891 TI - Effects of angiotensin and norepinephrine infusions on total plasma volume and extracellular fluid space in man. PMID- 4295892 TI - In vivo dialysis of faeces as a method of stool analysis. 3. The effect of intestinal antibiotics. PMID- 4295893 TI - Early and late after discharges of amphibian sympathetic ganglion cells. PMID- 4295894 TI - [Antiviral activity of thiazole-thiourea derivatives]. PMID- 4295895 TI - [Studies of oligosaccharides. VII. Fractionation and effect on tumor cells of the acid hydrolysate of chondroitin sulfate]. PMID- 4295897 TI - Speaking out. On: principle and responsiblity. PMID- 4295896 TI - Community mental health in the Netherlands. The story of Dr. Arie Querido. PMID- 4295898 TI - Psychiatric drugs and trends. The weapon--education...the target--drug abuse. PMID- 4295899 TI - Rescue fantasy in the nurse therapist relationship with a psychotic child. PMID- 4295901 TI - Teaching behavioral observation to psychiatric nursing students. PMID- 4295900 TI - The nurse therapist. PMID- 4295902 TI - Hypothalmic-pituitary-adrenal function in thyrd disorders: effects of methopyrapone infusion on plasma corticosteroids. PMID- 4295903 TI - The antigenic use of periodate-treated adrenocorticotropic hormone (ACTH). PMID- 4295904 TI - Conformational changes of acetylcholinesterase. PMID- 4295905 TI - Inhibition of yeast alcohol dehydrogenase by N1-benzylpyridinium chlorides. PMID- 4295906 TI - Pulmonary and mediastinal lymphography. PMID- 4295907 TI - Total myelography with radiopaque emulsions. PMID- 4295908 TI - Several early angiographic findings in brain abscess including "the ripple sign". PMID- 4295909 TI - The diagnosis of intracranial cysts by means of the brain scan. PMID- 4295910 TI - Angiography of Wilms's tumor. PMID- 4295911 TI - [Histoenzymatic variations in the cells of Ehrlich's ascitic and solid tumors]. PMID- 4295912 TI - [Lysosome changes in mice with Ehrlich's ascitic and solid tumors]. PMID- 4295913 TI - Immunochemical studies of foot-and-mouth disease. II. Characterization of RNA free viruslike particles. PMID- 4295914 TI - A quantitative electron microscopic study of the virus particles found in cells infected with Rous sarcoma virus. PMID- 4295915 TI - Amino acid composition and C-terminal sequence of foot-and-mouth disease virus protein. PMID- 4295916 TI - Reversible inhibition of induction of mengovirus RNA polymerase and of virus maturation in Novikoff rat hepatoma cells by phenethyl alcohol. PMID- 4295917 TI - Development of S and T antigens and oncogenicity in hamster embryonic cell lines exposed to SV40. PMID- 4295918 TI - Internuclear transfer of SV40-T-antigen in absence of infectious virus. PMID- 4295919 TI - Studies on the mechanism of enhancement of adenovirus 7 infection in African green monkey cells by simian virus 40: formation of adenovirus-specific RNA. PMID- 4295920 TI - Surface layer in tumor cells transformed by adeno-12 and SV40 viruses. PMID- 4295921 TI - Paromomycin in the treatment of intestinal amebiasis; a short course of therapy. PMID- 4295922 TI - Plasma "cortisol" response to Synacthen in patients on long-term small-dose prednisone therapy. PMID- 4295923 TI - Hypothalamo-pituitary-adrenal function in patients on long-term adrenocorticotrophin therapy. PMID- 4295924 TI - Electron microscope observation of herpes-like particles in the iris. PMID- 4295925 TI - Ultrastructure of tumor cells during mitosis. PMID- 4295926 TI - Ultracytochemical studies on aberrant structures in avian virus tumor cells. PMID- 4295927 TI - Rectal and colonic mucosal biopsy findings and faeces, sigmoidoscopy, and histopathological correlation in amoebiasis and other colitis. PMID- 4295928 TI - Mercury(II) stimulation of malate dehydrogenase activity. PMID- 4295929 TI - The 6-O-methylglucose-containing lipopolysaccharide of Mycobacterium phlei. Identification of D-glyceric acid and 3-O-methyl-D-glucose in the polysaccharide. PMID- 4295930 TI - Serial hormone assays in a patient with secondary amenorrhoea treated with clomiphene and gonadotrophins. PMID- 4295931 TI - Synthesis of a protected C-terminal delta-aminovaleric acid analog of the peptide sequence occurring at positions 11-19 in adrenocorticotropins. PMID- 4295932 TI - A collagenaselike substance produced by eggs of Schistosoma mansoni. PMID- 4295933 TI - Cowper's gland carcinoma. Report of a case. PMID- 4295934 TI - Problems of correct interpretation of radioisotope renograms: experimental observations and clinical experiences. PMID- 4295935 TI - [Cross-resistance relationship among capreomycin, kanamycin, viomycin and streptomycin resistance of Mycobacterium tuberculosis]. PMID- 4295936 TI - Insulin-secreting tumors of the pancreas. PMID- 4295937 TI - Primary tumors and cysts of the mediastinum. PMID- 4295938 TI - Inhibitory effect of 1,2-bis(2-benzimidazolyl)-1,2-ethanediol derivatives on poliovirus. PMID- 4295939 TI - High titre T antigen with minimal amounts of structural antigen in adenovirus infected cells treated with hydroxyurea. PMID- 4295940 TI - Polyoma virus-induced release of inhibition of cellular DNA synthesis caused by iododeoxyuridine. PMID- 4295941 TI - Effect of cocaine, desipramine and angiotensin on uptake of noradrenaline in tissues of pithed rats. PMID- 4295942 TI - Holographic model of temporal recall. PMID- 4295943 TI - Electron spin resonance study of nitroxide radicals from diethylhydroxylamine, dioctylhydroxylamine and n-hydroxypyrrolidine. PMID- 4295944 TI - Failure to induce transplantation resistance against polyoma tumour cells with syngeneic embryonic tissues. PMID- 4295945 TI - Effect on the guinea-pig taenia coli of the substitution of strontium or barium ions for calcium ions. PMID- 4295946 TI - External chemical messengers. IV. Pineal gland. PMID- 4295947 TI - Gas chromatography for detection of viral infections. AB - Gas chromatograms of sertim extracts of dogs inoculated with canine infectious hepatitis virus showed two metabolites not observed in uninoculated animals. Chromatograms of extracts of tissue cultures of dog kidney, inoculated with viruses causing canine hepatitis, herpes, and distemper, and a parainfluenza virus similar to simian virus-5, each showed two or more different metabolites. Two of the distinguishing products from cultures inoculated with hepatitis virus were chromatographically indistinguishable from those found in serums of the animals. PMID- 4295948 TI - Dimethyl sulfoxide: an inhibitor of liver alcohol dehydrogenase. AB - Dimethyl sulfoxide inhibits horse liver alcohol dehydrogenase. In the direction of aldehyde reduction, this inhibition is competitive with aldehyde, with an inhibition constant of 5 x 10(-3)M. Dimethyl sulfoxide reacts with the binary complex consisting of enzyme and the reduced form of nicotinamide -adenine dinucleotide to form a highly fluorescent ternary complex, with a dissociation constant similar to the inhibition constant. The inhibition of aldehyde reduction can be interpreted as due to competition between aldehyde and dimethyl sulfoxide for the carbonyl binding site of the above-mentioned binary complex. PMID- 4295949 TI - The presence of human enteric viruses in sewage and their removal by conventional sewage treatment methods. PMID- 4295950 TI - Effect of angiotensin and norepinephrine upon urate clearance in man. PMID- 4295951 TI - Eosinophilic spongiosis in pemphigus. A report of an unusual hitological change in pemphigus. PMID- 4295952 TI - Pseudomonas aeruginosa in dermatology. PMID- 4295953 TI - Aerobic glycolysis, oxygen uptake, and enzyme activity of the electron transport system in neoplastic and non-neoplastic ovarian tissue grafted into the spleen of C57BL mice. PMID- 4295954 TI - The influence of whole-body exposure to x-rays or neutrons on the life span distribution of tumors among male rats. PMID- 4295955 TI - Ribonuclease activity of ribonucleoprotein particles isolated from livers of rats fed 4-dimethylaminoazobenzene, primary liver tumors, and Novikoff hepatoma. PMID- 4295956 TI - Base compositions of RNA of nuclear fractions obtained by sequential extraction with saline solutions. PMID- 4295957 TI - Hormonal control of ascorbic acid transport in rat adrenal glands. PMID- 4295958 TI - Site of action of trophic hormones upon the biosynthetic pathways to steroid hormones. PMID- 4295959 TI - Species differences in inducibility of phenylethanolamine-N-methyl transferase. PMID- 4295960 TI - Effects of androgens on incorporation of labeled amino acids into proteins by prostate mitochondria. PMID- 4295961 TI - Inhibition of adrenal progesterone biosynthesis by 3',5'-cyclic AMP. PMID- 4295962 TI - Homotransplantation of articular cartilage and isolated chondrocytes. An experimental study in rabbits. PMID- 4295963 TI - Phospholipids in the nervous system of molluscs. PMID- 4295964 TI - [Quantitative distribution of phospholipids in neurons and glial cells isolated from rat cerebral cortex]. PMID- 4295965 TI - Localization of gamma-aminobutyric-alpha-oxoglutaric acid transaminase in mouse brain. PMID- 4295966 TI - Effect of certain drugs on perfused human placenta. 8. Angiotensin-II antagonists. PMID- 4295967 TI - Intracranial aneurysm with panhypopituitarism with associated aneurysms of thoracic and abdominal aortas. PMID- 4295968 TI - Sero-epidemiological study of cytomegalovirus infections in Melbourne children and some adults. PMID- 4295969 TI - Isolation of human cytomegalovirus from the circulating leucocytes of a leukaemic patient. PMID- 4295970 TI - Peptide inhibitors of the renin-angiotensin system. PMID- 4295971 TI - Herpesvirus infection of human mesodermal tissue (cornea) detected by electron microscopy. PMID- 4295972 TI - Stimulus-induced release of substances from olfactory bulb using the push-pull cannula. PMID- 4295973 TI - Functioning islet cell adenoma in the newborn. Report of a case with failure of diazoxide. PMID- 4295974 TI - Quantitative gas chromatography of adrenal cortical steroids. PMID- 4295975 TI - Identification of estra-1,3,5(10),16-tetraen-3-ol (estratetraenol) from the urine of pregnant women (1). PMID- 4295976 TI - Reduced quinolines and quinolinium compounds. I. Reduction of quinoline analogs of model compounds for coenzyme I. PMID- 4295977 TI - [Histological and histochemical changes in the placental villi following cobalt administration]. PMID- 4295978 TI - Determination of blood corticoids using the in vitro resin uptake of 3H prednisolone. PMID- 4295979 TI - Studies on the hydrolysis of gel-filtered urinary oestrogens. PMID- 4295980 TI - The lipid-mobilizing effect of some pituitary gland perparations. II. Preparation of a human pituitary lipid-mobilizing factor (LMF) with hypocalcaemic and hyperglycaemic effects in rabbits. PMID- 4295981 TI - A regenerating system for studies of phosphoryl transfer from ATP. PMID- 4295982 TI - Separation of water-soluble steroid and carotenoid precursors by DEAE-cellulose column chromatography. PMID- 4295983 TI - A factor for coupling NAD to hydrogenase in Hydrogenomonas eutropha. PMID- 4295984 TI - Inhibition of the multiplication of Myxovirus and Arbovirus by chemically modified ribonucleic acids from the host cells. PMID- 4295985 TI - Fluorescence of D-glyceraldehyde-3-phosphate dehydrogenase-substrate complexes. PMID- 4295986 TI - Studies on alkaline phosphatase. Phosphorylation of calf-intestinal alkaline phosphatase by 32P-labelled pyrophosphate. AB - 1. A purified preparation of alkaline phosphatase from calf-intestinal mucosa was phosphorylated by (32)P-labelled PP(i) at a serine residue on the enzyme. Under the conditions employed, up to 0.15mum-labelled sites were obtained from 1mum [(32)P]PP(i). 2. The phosphorylated enzyme was labile, the rate of dephosphorylation being similar to the overall rate of substrate hydrolysis. 3. A stopped-flow technique was used to determine the number of phosphomonoesterase active sites, which agreed with the number of (32)P-labelled sites. 4. It is concluded that calf-intestinal alkaline phosphatase is both a phosphomonoesterase and a pyrophosphatase. PMID- 4295987 TI - Mass-spectrometric evidence for methyl and ethyl esters of long-chain fatty acids in ox pancreas. PMID- 4295988 TI - The isolation of rat liver plasma membrane fragments. PMID- 4295989 TI - Glucose and mannose diphosphates in the red blood cell. PMID- 4295990 TI - Glucose as a regulator of glycogen phosphorylase in rat diaphragm. II. Effect of glucose and related compounds on phosphorylase phosphatase. PMID- 4295991 TI - The isolation of a mutant of Bacillus cereus deficient in phosphate uptake. PMID- 4295992 TI - Acetylcholine-sensitivity of thalamic neurones: its relationship to synaptic transmission. PMID- 4295993 TI - Histochemical differentiation in beagle aorta. PMID- 4295994 TI - Iron utilization and metabolism in the chick. PMID- 4295995 TI - [Malignant tumor of the thymus and Cushing's syndrome]. PMID- 4295996 TI - [Recent progress in the knowledge of acute pancreatitis]. PMID- 4295997 TI - [Value and limitation of the perfusion test with angiotensin]. PMID- 4295998 TI - [What is the current status of therapeutic possibilities in severe juandice?]. PMID- 4295999 TI - [Is the herpes virus responsible for acute necrotizing encephalitis?]. PMID- 4296000 TI - [Hepatography using lipiodol by trans-splenic route. Experimental study. Preliminary clinical results]. PMID- 4296001 TI - [Our experience with acute necrotizing encephalitis. Demonstration of herpes virus by the electron microscope]. PMID- 4296002 TI - [Application of contrast-increasing methods in abrodil myelography]. PMID- 4296003 TI - Experimental studies of intralymphatic administration of radiotherapy with particular emphasis on lymphatic dynamics and lymph node response to lymphography. PMID- 4296004 TI - Lymphographic evaluation of abnormal lymph flow in protein-losing gastroenteropathy secondary to chronic constrictive pericarditis. PMID- 4296005 TI - 99mTc pertechnetate scanning of salivary glands. PMID- 4296006 TI - Cerebral synaptic transmission and behavioral effects of dimethoxyphenylethylamine: a potential psychotogen. AB - Dimethoxyphenylethylamine, like mescaline which it resembles, impairs cerebral synaptic transmission and behavior in cats. It has properties associated with hallucinogens and, on this score, qualifies as a potential inducer of psychosis. The idea of such an endogenous inducer is thus reaffirmed by the candidacy of dimethoxyphenylethylamine. PMID- 4296007 TI - Terminals of single Ia fibers: distribution within a pool of 300 homonymous motor neurons. AB - The excitatory postsynaptic potentials produced in motoneurons by impulses in single afferent fibers (Ia) have been recorded with the aid of an averaging computer. These responses were used to map the distribution of the terminals of single fibers within the pool of 300 motoneurons of the medial gastrocnemius muscle. Twelve Ia fibers were studied in separate experiments. Monosynaptic excitatory postsynaptic potentials were found in 94 percent of the 77 motoneurons investigated. This finding indicates that each of the 300 motoneurons must receive afferent fibers from almost all of the spindles of the muscle it innervates. PMID- 4296008 TI - [1st clinical experiences with treatment of hypophyseal tumors with cobalt-60 Kleinfeld pendulum irradiation]. PMID- 4296009 TI - [The importance of special outpatient clinics for vascular diseases]. PMID- 4296010 TI - Corticotrophin treatment in multiple sclerosis. PMID- 4296011 TI - Lactate and pyruvate levels in blood, cerebrospinal fluid and brain tissue. PMID- 4296012 TI - Zoster in children. PMID- 4296013 TI - Herpesvirus hominis (simplex) infection with recurrences during infancy. PMID- 4296014 TI - Ring-G chromosome, a new G-deletion syndrome? PMID- 4296015 TI - The mechanism of action of CDP-glucose oxidoreductase. PMID- 4296016 TI - Crystalline transfer factors from Escherichia coli. PMID- 4296017 TI - The energy-dependent accumulation of phosphate by blowfly mitochondria and its effect on the rate of pyruvate oxidation. PMID- 4296018 TI - Requirement of substrate for adenosine 5'-monophosphate binding to liver fructose 1,6-diphosphatase. PMID- 4296019 TI - A re-evaluation of the fractionation of high molecular weight RNA by MAK chromatography. PMID- 4296020 TI - Enzymatic solubilization of microsomal NADH-cytochrome b5 reductase by lysosomes. PMID- 4296021 TI - Studies on the respiratory chain-linked reduced nicotinamide-adenine dinucleotide dehydrogenase. I. Effect of diethyl ether on particulate NADH dehydrogenase. PMID- 4296022 TI - Induction of respiratory deficiency by repression of the respiratory system in a mutant of Saccharomyces cerevisiae. PMID- 4296023 TI - Composition and properties of the membrane-bound respiratory chain system of Micrococcus denitrificans. PMID- 4296024 TI - Light-induced electron transport in Chromatium strain D. I. Isolation and characterization of Chromatium chromatophores. PMID- 4296025 TI - Light-induced electron transport in Chromatium strain D. II. Light-induced absorbance changes in Chromatium chromatophores. PMID- 4296026 TI - Electron paramagnetic resonance studies on photosynthetic bacteria. I. Properties of photo-induced EPR-signals of Chromatium D. PMID- 4296027 TI - Brain and consciousness. PMID- 4296028 TI - Effects of cooling and rewarming on Na, K, and tension changes in rat tail artery. PMID- 4296029 TI - Studies of the energy-transfer system of submitochondrial particles. I. Competition between oxidative phosphorylation and the energy-linked nicotinamide adenine dinucleotide transhydrogenase reaction. PMID- 4296030 TI - Studies of the energy-transfer system of submitochondrial particles. 2. Effects of oligomycin and aurovertin. PMID- 4296031 TI - A polyribonucleotide containing alternation P=O and P=S linkages. PMID- 4296032 TI - [Modification of Aschaffenburg-Mullen technic for the determination of milk phosphatase]. PMID- 4296034 TI - [The effect of aminopeptidase on experimental renal hypertension in rats]. PMID- 4296033 TI - [Enzyme patterns of benign and malignant changes in human tissue. Enzyme studies on human tumors. 3]. PMID- 4296035 TI - A review of the experimental aspects of Bell's palsy. PMID- 4296036 TI - [Torn test and leukocytose test after simultaneous administration of ACTH in children with infectious nonspecific polyarthritis]. PMID- 4296037 TI - Problems relating psychological and electrophysiological observations in sensory perception. PMID- 4296038 TI - Molecular mechanisms in learning. PMID- 4296039 TI - [Thin layer chromatographic separation of vitamin A alcohol and calciferolen]. PMID- 4296040 TI - Energy transfer in poly-l-tyrosine as a function of the degree of ionization of the phenolic hydroxyls. II. Electron spin resonance study of the triplet state. PMID- 4296041 TI - The mechanism of internuclear transmission of SV40-induced complement fixation antigen in heterokaryocytes. PMID- 4296042 TI - Effect of phenoxybenzamine on neural and humoral control of sweat glands. PMID- 4296043 TI - In vitro cultivation of mouse mammary tumor virus: detection of MTV production by radioisotope labeling and identification by immune precipitation. PMID- 4296044 TI - Evidence for large precursor proteins in poliovirus synthesis. PMID- 4296045 TI - [The treatment of shock with isoproterenol]. PMID- 4296046 TI - [The diagnosis of pharyngo-conjunctival fever]. PMID- 4296047 TI - [Technical advantages in main bronchus resection right and left]. PMID- 4296048 TI - Clinical vestibular examinations and their results. PMID- 4296049 TI - Theca cell tumor. An ultrastructural study. PMID- 4296050 TI - The changing prognosis and treatment in cancer of the ovary. A report of 235 patients with primary ovarian carcinoma 1952-1961. PMID- 4296051 TI - Synthesis of 4-O-beta-D-glucopyranosyl-D-xylose. 4-O-beta-D-glucopyranosyl-D arabinose, 4-O-beta-D-glucopyranosyl-2-deoxy-D-glucose, 4-O-beta-D-glucopyranosyl D-mannose, and 4-O-beta-D-glucopyranosyl-D-glucosamine by cellobiose phosphorylase from Clostridium thermocellum. PMID- 4296052 TI - Pyridine nucleotide changes during thermogenesis in brown fat tissue in vivo. PMID- 4296053 TI - Trihydroxycoprostanic acid from crocodilians. PMID- 4296054 TI - The pathway of biosynthesis of nicotinamide-adenine dinucleotide in rat mammary gland. AB - 1. The pathway of NAD synthesis in mammary gland was examined by measuring the activities of some of the key enzymes in each of the tryptophan, nicotinic acid and nicotinamide pathways. 2. In the tryptophan pathway, 3-hydroxyanthranilate oxidase and quinolinate transphosphoribosylase activities were investigated. Neither of these enzymes was found in mammary gland. 3. In the nicotinic acid pathway, nicotinate mononucleotide pyrophosphorylase, NAD synthetase, nicotinamide deamidase and NMN deamidase were investigated. Both NAD synthetase and nicotinate mononucleotide pyrophosphorylase were present but were very inactive. Nicotinamide deamidase, if present, had a very low activity and NMN deamidase was absent. 4. In the nicotinamide pathway both enzymes, NMN pyrophosphorylase and NMN adenylyltransferase, were present and showed very high activity. The activity of the pyrophosphorylase in mammary gland is by far the highest yet found in any tissue. 5. The apparent K(m) values for the substrates of these enzymes in mammary gland were determined. 6. On the basis of these investigations it is proposed that the main, and probably only, pathway of synthesis of NAD in mammary tissue is from nicotinamide via NMN. PMID- 4296055 TI - A direct pathway for the conversion of propionate into pyruvate in Moraxella lwoffi. AB - 1. The identity of the organism previously known as Vibrio O1 (N.C.I.B. 8250) with a species of Moraxella is established. 2. The ability of cells to oxidize propionate is present only in cells with an endogenous respiration and this ability is increased 80-fold when the organism is grown with propionate. 3. Isocitrate lyase activity in extracts from propionate-grown cells is the same as that in extracts from lactate-grown cells, about tenfold greater than that in extracts from succinate-grown cells and slightly greater than half the activity in extracts from acetate-grown cells. 4. With arsenite as an inhibitor conditions were found in which the organism would catalyse the quantitative oxidation of propionate to pyruvate. When propionate was completely utilized pyruvate was metabolized further to 2-oxoglutarate. 5. The oxidation of propionate by cells was incomplete both in a ;closed system' with alkali to trap respiratory carbon dioxide and in an ;open system' with an atmosphere of oxygen+carbon dioxide (95:5). Acetate accumulated. Under these conditions [2-(14)C]- and [3-(14)C] propionate gave rise to [(14)C]acetate. The rate of conversion of [2 (14)C]propionate into (14)CO(2), although much less than the rate of conversion of [1-(14)C]propionate into (14)CO(2), was slightly greater than the rate of conversion of [3-(14)C]propionate into (14)CO(2). 6. The oxidation of propionate by cells was complete in an ;open system' with an atmosphere of either oxygen or air. Under these conditions very little [1-(14)C]propionate was converted into (14)C-labelled cell material. The conversion of [2-(14)C]- and [3-(14)C] propionate into (14)C-labelled cell material occurred at an appreciable rate, the rate for the incorporation of [3-(14)C]propionate being slightly more rapid. In the absence of a utilizable nitrogen source part of the [(14)C]propionate was incorporated into some reserve material, which was oxidized when added substrate had been completely utilized. 7. [(14)C]-Pyruvate produced from [(14)C]propionate was chemically degraded. The C((1)) of propionate was found only in C((1)) of pyruvate. At least 86% of C((2)) of pyruvate was derived from C((2)) of propionate and at least 92% of C((3)) of pyruvate from C((3)) of propionate. 8. These results are incompatible with the operation of any of the previously described pathways for propionate metabolism except the direct one, perhaps via an activated acrylate. PMID- 4296056 TI - Effect of a lipid extract of frog skin on short-circuit current and sodium transport of isolated frog skin. PMID- 4296057 TI - Irreversible inactivation of (Na+-K+)-dependent ATPase and K+-dependent phosphatase by fluoride. PMID- 4296058 TI - The conformation dependent hydrolysis of DNA by micrococcal nuclease. PMID- 4296059 TI - Repression of isocitrate lyase synthesis in seeds germinated in the presence of glucose. PMID- 4296060 TI - The effect of 1,1,1-trichloro-2,2-bis(para-chlorophenyl)ethane on ribonucleic acid metabolism in Musca domestica L. PMID- 4296061 TI - Degradation of thymus DNA and crab poly d(A-T) by micrococcal nuclease in the presence of actinomycin D. PMID- 4296062 TI - [Fractionation study of the ribonucleic acids of Escherichia coli by filtration on dextran del]. PMID- 4296063 TI - [Extraction of polyphosphoinositides from rat brain. Application to the determination of polyphosphoinositides]. PMID- 4296064 TI - [In vitro metabolism of adipose tissue. V. Heterogeneity and subheterogeneity of the pool of NEFA in epididymal adipose tissue in the normal mouse. In vitro effects of glucose, adrenalin and insulin]. PMID- 4296065 TI - [Biochemical study of plankton. II. onsaponifiables and sterols of a plankton marine animal]. PMID- 4296066 TI - [Chemotaxonomic research on vascular plants. One the presence of 6-methylchrysin in the fern Lonchitis tisserantii Alston and Tardieu]. PMID- 4296067 TI - [Elevation of the so-called prostatic acid phosphatase in women]. PMID- 4296068 TI - Evidence for dual physiological formsof ergosterol in Saccharomyces cerevisiae. PMID- 4296069 TI - Comparison of the effect of the pyrogens, etiocholanolone and bacterial endotoxin on plasma cortisol and growth hormone in man. PMID- 4296070 TI - Clinical evaluation of urinary cortisol determinations by competetive protein binding radioassay. PMID- 4296071 TI - Effect of estrogens on mature height in tall girls: a controlled study. PMID- 4296072 TI - Growth hormone secretion enhanced by androgens. PMID- 4296073 TI - Lysosomes in the spleen of the chick embryo. I. Description in the normal spleen. PMID- 4296074 TI - Lysosomes in the spleen of the chick embryo. II. Changes during the graft-versus host reaction. PMID- 4296075 TI - Histological and histochemical observations of the hemolymph cells in the crayfish, Orconectes virilis. PMID- 4296076 TI - Insulin-secreting bronchial carcinoid tumor with widespread metastases. PMID- 4296077 TI - Multiple primary carcinomas of the breast and stomach. PMID- 4296078 TI - Granular cell myoblastoma of the breast. PMID- 4296079 TI - Herpes simplex virus infections of the nervous system. Problems in laboratory diagnosis. PMID- 4296080 TI - Myotubular myopathy. PMID- 4296081 TI - Concentration of technectium 99m by the choroid plexus. Experimental demonstration in vivo. PMID- 4296082 TI - The effect of triiodthyronine on neuromuscular junctions of isolated rat diaphragm. PMID- 4296083 TI - Identification and estimation of tritium-labeled reserpine in biological material by a combination of thin-layer chromatography and liquid-scintillation radioassay. PMID- 4296084 TI - Renal effects of val 5-angiotensin 11-amide, vasopressin and diuretics in the rat, as influenced by water diuresis and by ethanol anesthesia. PMID- 4296085 TI - Functional identity of rat-liver microsomal glucose 6-phosphatase and inorganic pyrophosphatase. PMID- 4296086 TI - Liver response tests. 8. Factors influencing the activities of liver-microsomal phosphatases. PMID- 4296087 TI - Effects of x-irradiation on the synthesis of rapidly labelled RNA in experimental tumour of the rat. PMID- 4296088 TI - Free radical yields in x-irradiated glycine peptides. PMID- 4296089 TI - Free radical formation in a gamma-irradiated pyrimidine-purine co-crystal complex. PMID- 4296090 TI - Case report: granular cell myoblastoma. PMID- 4296091 TI - Nerve conduction and the effect of local anesthesia. PMID- 4296092 TI - A note on foot and mouth disease. (Epizootic aphtha). PMID- 4296093 TI - Skeletal maturation in juvenile diabetes mellitus. PMID- 4296094 TI - Mechanism of action and metabolic fate of vitamin D. PMID- 4296095 TI - A case of migratory intraocular foreign body. PMID- 4296096 TI - Comparison of the in vitro cytology of hamster embryo cell lines transfored "spontaneously" or by SV40: with contrast of sarcomas induced in the homologous host. PMID- 4296097 TI - Supporting role of the adrenal cortex in the induction of hyperfibrinogenemia. PMID- 4296098 TI - Histidinaemia: a child and his family. PMID- 4296099 TI - [The toxicity of acrylonitrile]. PMID- 4296100 TI - Mixed tumors of human salivary gland. Histogenesis. PMID- 4296101 TI - Serum folate and FIGLU excretion in patients with trophoblastic tumours. PMID- 4296102 TI - Genetic and viral influences of mammary tumours in BR6 mice. PMID- 4296103 TI - [On the fate of patients with occupational dermatitis]. PMID- 4296104 TI - Routine preparation of silica gel media using silicate solutions of varying pH. PMID- 4296105 TI - Heterogeneity in the properties of 7 S and 19S rabbit-neutralizing antibodies to herpes simplex virus. PMID- 4296106 TI - Interaction of some polyvinyl pyridine oxides with polysilicic acid and its relationship to their ability to inhibit silica fibrosis. PMID- 4296107 TI - Molecular conformation of thymidine and a comparison with some electron spin resonance results. PMID- 4296108 TI - Identification of rhinovirus stran D.C. PMID- 4296109 TI - Neurotrophic control of contracture in slow muscle fibres. PMID- 4296110 TI - Paget's disease of the vulva. Report of 10 cases. PMID- 4296111 TI - Maternal urinary estriol excretion after dehydroepiandrosterone-sulfate infusion and adrenal stimulation and suppression. PMID- 4296112 TI - Nasopharyngeal angiofibroma in the juvenile. PMID- 4296113 TI - The laboratory diagnosis of human parasitic amoebae. PMID- 4296114 TI - The influence of food intake and ergot alkaloids upon vagogenic atrioventricular heart block of the Wenckebach type. PMID- 4296115 TI - The clinical significance of lymphatico-venous anastomosis. Its implications in lymphangiography. PMID- 4296116 TI - [A case of the auriculo-temporal syndrome of Frey]. PMID- 4296117 TI - Pregnancy following Wilms' tumor. PMID- 4296119 TI - Malignant tumors in smallpox vaccination scars: a report of 24 cases. PMID- 4296118 TI - Cytochemical and ultrastructural studies of the intestinal mucosa of children with celiac disease. PMID- 4296120 TI - Activity of enzymes in the endometrium, caruncles, and uterine rinsings of progestogen-treated and naturally cycling ewes. PMID- 4296121 TI - Electric dipole theory of chemical synaptic transmission. AB - In this paper we propose that chemicals such as acetylcholine are electric dipoles which when oriented and arranged in a large array could produce an electric field strong enough to drive positive ions over the junction barrier of the post-synaptic membrane and thus initiate excitation or produce depolarization. This theory is able to explain a great number of facts such as cleft size, synaptic delay, nonregeneration, subthreshold integration, facilitation with repetition, and the calcium and magnesium effects. It also shows why and how acetylcholine could act as excitatory or inhibitory transmitters under different circumstances. Our conclusion is that the nature of synaptic transmission is essentially electrical, be it mediated by electrical or chemical transmitters. PMID- 4296122 TI - Changes in blood vessel permeability during degeneration and regeneration in peripheral nerves. PMID- 4296123 TI - The enzymatic assay of pyruvic and lactic acids. A definitive procedure. PMID- 4296124 TI - An improved method for measuring human blood bile acids. PMID- 4296125 TI - Two-deimensional thin-layer chromatography of neuraminic acid-containing lipids. PMID- 4296126 TI - The relationship of NADH-dependent diaphorase activity and methemoglobin reduction in human erythrocytes. PMID- 4296127 TI - The metabolism of glyoxylate in blood from normal subjects and patients with primary hyperoxaluria. PMID- 4296128 TI - Electrophoretic characterization of amebal glucose phosphate isomerases. PMID- 4296129 TI - Metabolism of Plasmodium berghei. I. Krebs cycle. PMID- 4296130 TI - A study of bacteria and lethal factors in fluids from experimental intestinal obstruction in dogs. PMID- 4296131 TI - The foot and mouth disease virus content of guinea-pig epidermis after mechanical injury. PMID- 4296132 TI - Influence of irradiation on the susceptibility of the guinea-pig to infection with Clostridium welchii type A. PMID- 4296133 TI - Further investigations on enterovirus-neutralising substances in human and animal sera. PMID- 4296134 TI - Structure and function of mitochondria in crithidia fasciculata. PMID- 4296135 TI - Mouse hyperaemic corpora lutea assay of prolcatin. PMID- 4296136 TI - Prevention of bacteriuria resulting from indwelling catheters. PMID- 4296137 TI - [Lipid pattern of health human serum and cerebrospinal fluid in thin layer chromatography]. PMID- 4296138 TI - Bistability caused by substrate inhibition of peroxidase in an open reaction system. PMID- 4296139 TI - Amino-acid composition of "Tubulin" constituting microtubules of sperm flagella. PMID- 4296140 TI - Pressure effects on survival of mice with transplantable leukaemia. PMID- 4296141 TI - A case of congenital epulis. PMID- 4296142 TI - The nurse as a central figure in a medical health center. PMID- 4296143 TI - Analysis of the 5'-terminal nucleotide sequences of ribonucleic acids. II. Comparison of the 5'-terminal nucleotide sequences of ribosomal RNA's from different organisms. PMID- 4296144 TI - Herpes simplex encephalitis. PMID- 4296145 TI - [On the effect of D-and L-penicillamine on transaminase]. PMID- 4296146 TI - Measurement of plasma cortisol in the diagnosis of Cushing's syndrome. PMID- 4296147 TI - Smallpox studies in Madras City, India. PMID- 4296148 TI - Comparative studies of cell-culture-propagated avian pox viruses in chickens and turkeys. PMID- 4296149 TI - Susceptibility of turkeys to infectious laryngotracheitis. PMID- 4296150 TI - Infectious disease exposure in a wild turkey population. PMID- 4296151 TI - Focal degenerative myopathy in turkeys. PMID- 4296152 TI - A case of pancreatic disease with peptic ulceration. PMID- 4296153 TI - [A basic study on the affinity of encephalitis viruses for human tissues. Multiplication of Japanese B encephalitis and its related viruses in human tissue cultures]. PMID- 4296154 TI - Polynucleotidase activity of animal and plant tissue phosphodiesterases. PMID- 4296155 TI - Enzymatic oxidation of 14C-labelled betaine by the marine microbe Achromobacter cholinophagum. PMID- 4296156 TI - Liver glucokinase of the biotin deficient rat. PMID- 4296157 TI - The chain termini of polynucleotides formed by limited enzymic fragmentation of wheat embryo ribosomal RNA. 1. Studies of snake venom phosphodiesterase. PMID- 4296158 TI - Acute leukemias and Burkitt's lymphoma. Present status of therapy. PMID- 4296159 TI - Host defenses in leukemia and Burkitt's tumor. PMID- 4296160 TI - Tumors of the kidney in cattle, sheep and pigs. PMID- 4296161 TI - The parafollicular cells of the thyroid gland as a possible site of production of thyrocalcitonin. An electron microcopic examination of the thyroid gland of the rat after stimulation by calcium acetate and vitamin D3. PMID- 4296162 TI - [Influence of angiotensin on the argentaffin system of the guinea pig]. PMID- 4296163 TI - [Study of pituitary-adrenal function in bronchitic-asthmatic syndromes. I. ACTH and metopirone tests]. PMID- 4296164 TI - The cells of Cajal-Retzius in the developing human brain. PMID- 4296165 TI - A simple twenty-four hour test to evaluate hypothalamus-pituitary-adrenal cortical function. PMID- 4296166 TI - Changes in adrenocortical responsiveness to ACTH infusion in aging goats. PMID- 4296167 TI - Cytology of cerebrospinal fluid in the diagnosis of malignancy. PMID- 4296168 TI - Tritiated folic acid (H F.A.). Excretion tests for the study of folic acid absorption. PMID- 4296169 TI - Stimulation of the cat stellate ganglion by angiotensin. PMID- 4296170 TI - Electromechanical and pharmacomechanical coupling in vascular smooth muscle. PMID- 4296171 TI - On the presence of a renin-like activity in erythropoietin preparations. PMID- 4296172 TI - Hirano J, Masson GM: Effects of dietary sodium on hypertensive disease caused by renin. PMID- 4296173 TI - Islet cell tumor in the neonate. Studies in carbohydrate metabolism and therapeutic response. PMID- 4296174 TI - Inflammatory pseudotumors of the lung: a report of two cases and brief review of the literature. PMID- 4296175 TI - [The interaction of chickenpox virus with cells of the chick embryo chorio allantois]. PMID- 4296176 TI - Effect of some drugs on p-nitrophenylphosphatase activity in brain and live tissue of the rat with special reference to influence of phenothiazines on membranes of brain tissue. PMID- 4296177 TI - False adrenergic transmitter release from the isolated cat heart. PMID- 4296178 TI - Studies in hypophosphatasia and response to high phosphate intake. PMID- 4296179 TI - A pox disease in monkeys transmitted to man. Clinical and histological features. PMID- 4296180 TI - [Advantages of the evaluation of metacarpal and phalangeal nuclei for radiographical determination of bone age. Case studies of conenital adrenogenital syndrome]. PMID- 4296181 TI - Auditory function and lesions of the pons. PMID- 4296182 TI - Successful total adrenal autotransplantation into the spleen of dogs. PMID- 4296183 TI - A serological survey of mucosal disease and infectious bovine rhinotracheitis in cattle in Australia and New Guinea. PMID- 4296184 TI - Suspected adenovirus bronchitis in Arab foals. PMID- 4296185 TI - Canine distemper. PMID- 4296186 TI - The influence of cyclic 3', 5'-AMP and theophylline on oxygen consumption of rats. PMID- 4296187 TI - Base sequence differences between the ribosomal and "ribosomal precursor" ribonucleic acids from Ehrlich ascites cells. PMID- 4296188 TI - The filipin complex. PMID- 4296189 TI - Light-induced free radicals of retinal, retinol, and rhodopsin. PMID- 4296190 TI - Erythritol metabolism by Propionibacterium pentosaceum. The role of L-erythrulose 1-phosphate. PMID- 4296191 TI - A study of the conformational properties of bovine pancreatic ribonuclease A by electron paramagnetic resonance. PMID- 4296192 TI - Mechanisms of steroid oxidation by microorganisms. 13. C22 acid intermediates in the degradation of the cholesterol side chain. PMID- 4296193 TI - Mechanisms of steroid oxidation by microorganisms. XIV. Pathway of cholesterol side-chain degradation. PMID- 4296194 TI - Steroid treatment in the nephrotic syndrome in childhood. PMID- 4296195 TI - Synacthen Depot--Adrenal response in normal subjects and corticotrophin-treated patients. PMID- 4296196 TI - [regulation of the contribution of precursors of ribonucleic acids in the nuclei of animal cells]. PMID- 4296197 TI - [Transfer of nucleotides across the membrane of cell nuclei]. PMID- 4296198 TI - Inhibition of eledoisin by morin on the isolated guinea pig ileum. PMID- 4296199 TI - Patterns of three-dimensional growth in vitro in collagen-coated cellulose sponge: carcinomas and embryonic tissues. PMID- 4296200 TI - Electron spin resonance studies of photo-sensitized decomposition of methyl alcohol in the presence of p-benzoquinone. PMID- 4296201 TI - Proprties of ATP-ase of the BAI strain A virus. 3. Relationship of ATP-ase to the active transport of sodium and potassium ions. PMID- 4296202 TI - Antigens of the liver plasma membranes and mouse hepatoma. PMID- 4296203 TI - Comparative study of mouse leukaemias induced by Mazurenko, Friend and Graffi viruses, using the in vitro cytotoxic test. PMID- 4296204 TI - Biological oxidations and energy conservation. PMID- 4296205 TI - Lysosomes in the spleen of the chick embryo. I. Description in the normal spleen. PMID- 4296206 TI - Characterization of a herpes-like virus recovred from Burkitt lymphoma cells(P3 J) and propagated in dog thymus cells. 1. An electron microscope study. PMID- 4296207 TI - Characterization of a herpes-like virus recovered from Burkitt lymphoma cells(P3 J) and propagated in dog thymus cells. 1. An electron microscope study. PMID- 4296208 TI - Observations on the transformation of human amnion cell cultures by simian virus 40. PMID- 4296209 TI - Biological behavior through successive transplant generations of transplantable tumors derived originally from primary chemically induced and spontaneous sources in mice. PMID- 4296210 TI - Characteristics of the in vitro assay of murine sarcoma virus (Moloney) and virus infected cells. PMID- 4296211 TI - Observations on the nature of the herpes-type EB virus in cultured Burkitt lymphoblasts, using a specific immunofluorescence test. PMID- 4296212 TI - Studies on the acute inflammatory response. I. Involvement of the central nervous system in certain models of inflammation. PMID- 4296213 TI - [Excretion of 17-ketosteroid fractions in leukemic patients following ACTH therapy]. PMID- 4296214 TI - [Conformities of quartz-conditioned hemolysis]. PMID- 4296215 TI - [Hemolysis of warm and cold blood erythrocytes by quartz]. PMID- 4296216 TI - [Effect of some so-called antiproteolytics and hormones on release of thyroid hormones]. PMID- 4296217 TI - +On a procedure for determination of the adrenal cortex secreion rate of cortisol and dehydroepiandrosterone. PMID- 4296218 TI - [Results of transsphenoidal hypophysectomy with radiogold in consideration of the complications, problems following treatment and hormonal control]. PMID- 4296219 TI - [Results of primary and combined operative-stereotaxic irradiation of pituitary adenomas]. PMID- 4296220 TI - [Case of mucoepidermoid carcinoma of the parotid gland]. PMID- 4296221 TI - Questions of hospital patients--unasked and unanswered. PMID- 4296222 TI - Evaluation of management and therapy of the mentally retarded. PMID- 4296223 TI - [Study of adrenal cortex reserve; a rapid method]. PMID- 4296224 TI - Response of Ips confusus to synthetic sex pheromones in nature. AB - The first flight response of bark beetles to synthetic sex pheromones under natural conditions is reported. Two insect species predaceous on this bark beetle also responded. The synthetic compounds delivered in an airstream from a substrate of Carbowax 20M on Chromosorb A appear to elicit the same response as the natural attractant from male-infested bolts of ponderosa pine elicits. PMID- 4296225 TI - [Oxygen consumption and lipid peroxidation of the extramitochondral cytoplasmic fractions of liver and Yoshida's ascites hepatoma]. PMID- 4296226 TI - [Application of the isofixation technic in the complement fixation test for the intratypical differentiation of polio virus strains of type I]. PMID- 4296227 TI - The regulation of aldosterone secretion by the renin-angiotensin system under various conditions. PMID- 4296228 TI - Mycoplasma pharyngeal flora in civilians. PMID- 4296229 TI - Bronchial arterial perfusion with cytotoxic agents for bronchogenic carcinoma. Preliminary report. PMID- 4296230 TI - [Anthropology of New Ireland (Neumecklenburg) in the Melanesian South Sea. II. The observations on the collected skulls]. PMID- 4296231 TI - Tumours of salivary glands. A review of 204 cases with 5-year follow-up. PMID- 4296232 TI - The stability of the protective antigen and histamine-sensitizing factor of Bordetella pertussis to acid and alkali. PMID- 4296233 TI - Lipohyperplasia of the ileocecal valve. PMID- 4296234 TI - Susceptibility of various types of cell cultures to three strains of bovine parainfluenza 3 virus. PMID- 4296235 TI - Feline viruses. I. Characterization of four isolates and their effect on young kittens. PMID- 4296236 TI - The effect of 5-iodo-2'-deoxyuridine on the multiplication of infectious bovine rhinotracheitis virus. PMID- 4296237 TI - [On the diagnosis of adrenal cortex insufficiency]. PMID- 4296238 TI - Inhibition of fatty acid stimulation of gluconeogenesis by (+)-decanoylcarnitine in perfused rat liver. PMID- 4296239 TI - Studies on the mechanism of antilipolytic action of prostaglandin E1. PMID- 4296240 TI - [First attempts of pulmonary scintigraphy with a new tracer. Preliminary note]. PMID- 4296241 TI - Role of the redox state of nicotinamide adenine dinucleotides in the regulation of metabolic processes. PMID- 4296242 TI - The activation and inactivation of muscle phosphorylase. PMID- 4296243 TI - Deoxycorticosterone secretion in chronic experimental heart failure and during infusion of angiotensin II. PMID- 4296244 TI - Effects of antilymphocyte serum on virus oncogenesis. PMID- 4296245 TI - Influence of mammary tumor virus infection on the acceptance or rejection of transplanted ML+ leukemias. PMID- 4296246 TI - Serologic screening of rhesus and grivet monkeys for SV40 and the foamy viruses. PMID- 4296247 TI - Efficacy of interferon in the treatment of mice with established Friend virus leukemia. PMID- 4296248 TI - Further purification of a human placental inhibitor to hemagglutination by H-1 virus. PMID- 4296249 TI - Poliovirus replication and cytopathogenicity in monolayer hamster cell cultures fused with beta propiolactone-inactivated Sendai virus. PMID- 4296250 TI - Stimulatory effects of insulin and glucagon on phenylethanolamine-N-methyl transferase of rat adrenal. PMID- 4296251 TI - Rate of disappearance of exogenous dog renin from the plasma of nephrectomized dogs. PMID- 4296252 TI - Rhinoviruses: the isolation and characterization of three new serologic types. PMID- 4296253 TI - [Our experience with a new medication administered orally in the treatment of coronary insufficiency]. PMID- 4296254 TI - [Hemorrhages from uterine fibromyoma are not of organic origin, but purely functional and hormonal]. PMID- 4296255 TI - [Penicline in pediatrics]. PMID- 4296256 TI - [Injectable ampicillin. Study of its efficacy in operative sequelae in pediatric urology]. PMID- 4296257 TI - [Asthma and tuberculosis]. PMID- 4296258 TI - [Chronic pancreatitis and pleurisy]. PMID- 4296259 TI - [The peroral metoclopramide test in gastroduodenal radiology]. PMID- 4296260 TI - [New study of O.C.T. in minor hepatic disorders and sequelae of hepatitis]. PMID- 4296261 TI - [Use of assur in 103 cases of influenza and adenovirus infections]. PMID- 4296262 TI - [Systematic hormone determination and treatment with gonadotropins, estrogens and progesterone in the prevention of spontaneous abortion]. PMID- 4296263 TI - [The bradycardia-inducing effect of guanethidine]. PMID- 4296264 TI - [Study of fatigue and its physiopathologic consequences in subjects spending the winter in Antarctica]. PMID- 4296265 TI - [Apropos of the functional origin of certain types of chronic jaundice]. PMID- 4296266 TI - Comparison of reagent-impregnated paper strips and conventional methods for identification of Enterobacteriaceae. PMID- 4296267 TI - Fatal bronchial asthma: an analysis of terminal treatment in twenty cases. PMID- 4296268 TI - The pathogenesis of peritoneal adhesions: an ultrastructural study. PMID- 4296269 TI - Effect of cigarette smoke on resistance to respiratory infection. PMID- 4296270 TI - A clinical, roentgenological, and physiological study of magnetite workers. PMID- 4296271 TI - Pulmonary hazards of lymphography. PMID- 4296272 TI - Clinical and experimental studies of pulmonary oil embolism. PMID- 4296273 TI - Pulmonary function studies. PMID- 4296274 TI - Effect of variola and vaccinia viruses on the mitosis of cultured human amnion cells. PMID- 4296275 TI - Changes in the cortical thickness of the clavicle according to age. PMID- 4296276 TI - Sero-epidemiologic studies of Sendai virus infection on Taiwan. PMID- 4296277 TI - Experimental hypertrophic neuropathy: an electron microscope study. PMID- 4296278 TI - Arterial catecholamine and enzyme histochemistry in migraine. PMID- 4296279 TI - Recurrent cranial nerve palsies of dysglobulinaemic origin. PMID- 4296280 TI - Classification of the neuromuscular disorders. Appendix A to the Minutes of the Meeting of the Research Group on Neuromuscular Diseases, held in Montreal, Canada, on 21 September, 1967. PMID- 4296281 TI - [3H]uracil accumulation in motor neurons compared with that occurring in blocks of nerve tissue, liver, muscle and plasma in the rat. PMID- 4296282 TI - [A biochemical study on hepatic fibrosis due to low protein diet (soba powder)]. PMID- 4296283 TI - Immunization by selective infection with type 4 adenovirus grown in human diploid tissue cultures. I. Safety and lack of oncogenicity and tests for potency in volunteers. PMID- 4296284 TI - [On the study of the implantation of ascites tumor in urinary bladder. IV. Effect of antitumor agents (1)]. PMID- 4296285 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 19-1968. PMID- 4296286 TI - [Cushing's syndrome with pigmentation. (II)]. PMID- 4296287 TI - [Physiopathology and treatment of dysnatremia]. PMID- 4296288 TI - Demonstration by plaque reduction technique of immunologic relationship between canine herpes virus and herpes simplex virus. PMID- 4296289 TI - Effect of repeated inoculation of interferon preparations on infection of mice with encephalomyocarditis virus. PMID- 4296290 TI - Antibody to rhinovirus in human sera. I. Standardization of a neutralization test. PMID- 4296291 TI - Antibody to rhinovirus in human sera. II. Heterotypic responses. PMID- 4296292 TI - Pressor response to angiotensin II in hypertension. Correlation with plasma renin activity and response to norepinephrine and metaraminol. PMID- 4296293 TI - Glial-nodule encephalitis associated with generalized cytomegalic inclusion body disease. PMID- 4296294 TI - Fine structure of herpes simplex virus hepatoadrenal necrosis in the newborn. PMID- 4296295 TI - A general procedure for degrading radioactive aldoses. PMID- 4296296 TI - An evaluation of alumni group psychotherapy: for patients discharged from a group living program. PMID- 4296297 TI - [Scintigraphy with 203-Hg and 99m-Tc in the diagnosis of brain tumors]. PMID- 4296298 TI - [The treatment of gout and the internal medical treatment of uric acid nephrolithiasis]. PMID- 4296299 TI - [On the morphology of the lungs in virus diseases in infancy and childhood]. PMID- 4296300 TI - A new serologic test for adenovirus infection. PMID- 4296301 TI - Immunosuppression during acute murine cytomegalovirus infection. PMID- 4296302 TI - [Hygienic studies on baby powder. (1). Quartz and talc particles in lung preparations of the newborn infants and school children]. PMID- 4296303 TI - [Idiopathic orthostatic hypotension]. PMID- 4296304 TI - [Angiographic and histopathological study of supratentorial cerebral tumors. Casuistic contribution]. PMID- 4296305 TI - N-terminal disulphide knot of human fibrinogen. PMID- 4296306 TI - Fate of angiotensin I in the circulation. PMID- 4296307 TI - Wide distribution of leukaemia virus in strains of laboratory mice. PMID- 4296308 TI - The effects of pyrrolizidine alkaloids and d-tubocurarine on mitochondrial metabolism. PMID- 4296309 TI - Immune response of chickens following heat exposure or injections with ACTH. PMID- 4296310 TI - Free and conjugated steroid estrogen fractions of hens' urine. PMID- 4296311 TI - Liver opacification following lymphangiography: Pathogenesis and clinical significance. PMID- 4296312 TI - [Rare differential diagnosis of suspicious tuberculous spondylitis in early childhood]. PMID- 4296313 TI - [Adrenal gland neoplasms]. PMID- 4296314 TI - Influence of adrenocorticotrophic hormone on the DNA synthesis of epidermal and gastrointestinal cells in the mouse. PMID- 4296315 TI - Trnasglucosyl-amylase of Candida tropicalis. AB - Transglucosyl-amylase was purified 96-fold and partially characterized. The K(m) value with dextrin as substrate was 9.1 mg/ml. Glycerol, an acceptor of d glucose, appeared to inhibit dextrin hydrolysis noncompetitively. The energy of activation of the enzyme was 7,920 cal/mole. Indirect determinations showed that synthesis of d-glucosyl glycerol was significantly affected by the nature of the amylaceous substrate. Glucosyl-glycerol synthesis did not increase as incubation temperature was raised from 50 to 60 C. Direct determinations by gas-liquid chromatography indicated that the synthesis of glucosyl glycerol, as a function of the concentration of either enzyme, substrate, or glycerol, traced a curvilinear path approaching 15 mg/ml as the maximum. When enzyme, substrate, and glycerol at high concentrations were varied in all possible combinations, however, conditions for producing as much as 47.5 mg/ml of glucosyl glycerol were established. PMID- 4296316 TI - Synergism between hyperoxia and antibiotics for Pseudomonas aeruginosa. AB - Three strains of Pseudomonas aeruginosa were directly exposed on the surface of membrane filters to hyperoxic atmospheres. One of the three strains was found to be sensitive to oxygen. Colonies failed to appear during 18 hr of incubation in pure oxygen at 1 atm, but about 40% of the bacteria recovered to produce colonies upon reincubation in air. Similar killing was produced by 10 hr of oxygen exposure. No inhibition or killing was observed with two other strains. Streptomycin (1mug/ml) and kanamycin (5mug/ml) were more effective in killing the oxygen-sensitive strain in the presence of 60 to 70% oxygen than in air, but polymyxin B (5mug/ml) did not show a synergistic effect under such conditions. PMID- 4296317 TI - Stimulation by phenethyl alcohol of aerobic fermentation in Mucor rouxii. PMID- 4296318 TI - A split pathway of electron transport in mitochondria. PMID- 4296319 TI - Aldolase isozymes in rat tumor cells. PMID- 4296320 TI - Subcellular distribution of cytochrome c in rat liver. Methods for its extraction and purification. AB - 1. A method for the extraction and purification of cytochrome c from rat liver is described. The method depends on multiple chromatography on Amberlite IRC-50 with elution with ammonium phosphate buffers of differing ionic composition and pH, interspersed with gel filtration with Sephadex G-25. Conditions leading to denaturation are avoided and the product is chromatographically pure. 2. The method may be used for the quantitative analysis of cytochrome c either in unfractionated liver or in subcellular fractions. 3. Two pools of cytochrome c were detected, one extractable at pH4.0 with distilled water and the other extracted from the residues of the first extraction with 0.15m-sodium chloride. 4. For subcellular distribution studies the liver was homogenized in 0.3m-sucrose and a nuclear fraction (washed thoroughly to remove trapped mitochondria), a mitochondrial fraction, a heavy microsomal fraction, a standard microsomal fraction and the cell sap were isolated. The mitochondrial fraction was subfractionated further by density-gradient centrifugation. Each fraction was analysed for protein, RNA, DNA, succinate-neotetrazolium oxidoreductase and glucose 6-phosphatase. 5. A total of 123mug. of cytochrome c was obtained/g. wet wt. of rat liver. 6. Values for the percentage subcellular distribution of cytochrome c are: nuclear fraction, 24.4; mitochondrial fraction, 57.2; heavy microsomal fraction, 5.2; standard microsomal fraction, 10.6; cell sap, 2.7. 7. Three out of the eight mitochondrial subfractions separated by gradient centrifugation contained 76% of the cytochrome c and 85% of the succinate neotetrazolium oxidoreductase present in the mitochondrial fraction. 8. In unfractionated liver 94% of the cytochrome c was extracted at pH4.0 with water whereas in most of the subcellular fractions the corresponding value was approx. 75-80%. PMID- 4296321 TI - Studies on glycogen synthesis in pigeon liver homogenates. Glycogen synthesis from glucose monophosphates and uridine diphosphate glucose. AB - Comparative time-course studies of glycogen synthesis from glucose 6-phosphate, glucose 1-phosphate and UDP-glucose show that glucose 1-phosphate forms glycogen at an initial rate faster than that obtained with glucose 6-phosphate and UDP glucose. After 5min. the rates from glucose monophosphates are considerably slower. 2,4-Dinitrophenol decreases glycogen synthesis from both glucose monophosphates, whereas arsenate and EDTA increase glycogen synthesis from glucose 1-phosphate and inhibit the reaction from glucose 6-phosphate, galactose and galactose 1-phosphate. Mitochondria-free pigeon liver cytoplasmic fraction forms less glycogen from glucose monophosphates than does the whole homogenate. 2 Deoxyglucose 6-phosphate inhibits glycogen synthesis from glucose monophosphates. Glycogen formation from UDP-glucose is relatively unaffected by dinitrophenol, by arsenate, by EDTA, by 2-deoxyglucose 6-phosphate and by the removal of mitochondria from the whole homogenate. PMID- 4296322 TI - An improved synthesis of isopentenyl pyrophosphate. AB - 1. Isopentenol was converted into isopentenyl phosphate with phosphoryl chloride in ether containing pyridine. 2. The isopentenyl phosphate reacted in 2 methylpropan-2-ol-water with morpholine and dicyclohexylcarbodi-imide to give isopentenyl phosphoromorpholidate. 3. The isopentenyl phosphoromorpholidate, with inorganic phosphate in pyridine containing tributylamine, gave isopentenyl pyrophosphate. The yield of pyrophosphate from monophosphate was 80-85% and the yield of pyrophosphate from isopentenol 40-60%. [1-(14)C]-Isopentenyl pyrophosphate was prepared by this method. 4. The yield of isopentenyl pyrophosphate from isopentenyl phosphate was substantially improved, in comparison with the yields obtained by published methods via the phosphoramidate, by the use of the phosphoromorpholidate. PMID- 4296323 TI - Effect of mercurial compounds on structure-linked latency of lysosomal hydrolases. AB - 1. A partially purified lysosomal preparation was obtained from adult mouse livers by sucrose-density-gradient centrifugation of a large-granule fraction. 2. This lysosome-enriched subfraction was contaminated approx. 10% by mitochondrial cytochrome c oxidase and malate dehydrogenase. 3. Free acid phosphohydrolase and beta-glucuronidase contributed less than 10% of the total (Triton X-100 solubilized) activity in contrast with approx. 30% free N-acetyl-beta-d glucosaminidase when assayed in an iso-osmotic incubation system. 4. Exposure of the lysosomal preparation to inorganic Hg(2+) ions and organic mercurials (p chloromercuribenzoate, phenylmercuric acetate) induced an irreversible loss of structure-linked latency with resulting enzyme activation. 5. Maximal activation was related to log [Hg(2+)] and pH. The response was all-or-none for individual particles; the dose-response curve portrayed the variation in particle resistance within the lysosomal population. 6. l-Cysteine and GSH totally prevented Hg(2+) ion-induced hydrolase activation. Ascorbate provided approx. 50% protection. 7. The three lysosomal hydrolases were differentially activated at constant [Hg(2+)], suggesting a different pattern of binding, unique for each enzyme studied. PMID- 4296324 TI - Changes in hepatic lipigenesis during development of the rat. AB - 1. Changes in the activities of ATP citrate lyase, ;malic' enzyme, glucose 6 phosphate dehydrogenase, pyruvate kinase and fructose 1,6-diphosphatase, and in the ability to incorporate [1-(14)C]acetate into lipid have been measured in the livers of developing rats between late foetal life and maturity. 2. In male rats the activities of those systems directly or indirectly concerned in lipogenesis (acetate incorporation into lipid, ATP citrate lyase and glucose 6-phosphate dehydrogenase) fall after birth and are maintained at a low value until weaning. After weaning these activities rise to a maximum between 30 and 40 days and then decline, reaching adult values at about 60 days. ;Malic' enzyme activity follows a similar course, except that none could be detected in the foetal liver. Pyruvate kinase activity is lower in foetal than in adult livers and rises to slightly higher than the adult value in the post-weaning period. Fructose 1,6 diphosphatase activity rises from a very low foetal value to reach a maximum at about 10 days but falls rapidly after weaning to reach adult values at about 30 days. 3. Weaning rats on to a high-fat diet caused the low activities of acetate incorporation, ATP citrate lyase, glucose 6-phosphate dehydrogenase and pyruvate kinase, characteristic of the suckling period, to persist. ;Malic' enzyme and fructose 1,6-diphosphatase activities were not altered appreciably. 4. No differences could be detected in hepatic enzyme activities between males and females up to 35 days, but after this time female rats gave higher values for acetate incorporation, glucose 6-phosphate dehydrogenase activity and ;malic' enzyme activity. 5. The results are discussed in relation to changes in alimentation and hormonal influences. PMID- 4296325 TI - Nicotinamide-adenine dinucleotide-specific isocitrate dehydrogenase from pea mitochondria. Purification and properties. AB - 1. A method of stabilizing the enzyme by using glycerol is described. 2. A purification procedure is presented giving a higher purification than previously described. 3. Data showing substrate activation and activation by citrate are presented. 4. Kinetic constants for NAD(+), NADH and certain bivalent metal ions are given. 5. Pronounced inhibitory buffer effects are described. 6. A brief comparison between the NAD-specific isocitrate dehydrogenase from peas and that from other sources is made. PMID- 4296326 TI - The separation of vanillate O-demethylase from protocatechuate 3,4-oxygenase by ultracentrifugation. AB - 1. Protocatechuate 3,4-oxygenase in the soluble part of a cell-free extract of Pseudomonas fluorescens (strain T) sedimented more rapidly than vanillate O demethylase under specified conditions in a preparative ultracentrifuge. 2. The supernatant from this process contained vanillate O-demethylase and formaldehyde dehydrogenase, and when supplemented with NADH oxidized vanillate with an uptake of 1 mole of oxygen/mole of substrate and accumulation of protocatechuate. 3. This uptake was decreased to 0.5mole/mole of substrate in the presence of semicarbazide as trapping agent for formaldehyde. 4. Reasons are presented for the process of methyl group removal from vanillate being oxidative demethylation. PMID- 4296327 TI - Metabolic changes during phosphate deprivation in euglena in air and in oxygen. AB - 1. Euglena cells were grown in culture media containing either 20mm-phosphate or 20mum-phosphate, with ethanol or glucose as the sole source of carbon, and gassed with either air+carbon dioxide (95:5) or oxygen+carbon dioxide (95:5) at atmospheric pressure. 2. After growth in low-phosphate medium with ethanol as substrate, the cells developed signs of oxygen toxicity, as indicated by a decreased rate of respiration, a decreased net synthesis of paramylum and a failure to resume growth on replenishment of phosphate. 3. After growth in low phosphate medium with glucose as substrate, the signs of oxygen toxicity were less apparent. 4. During phosphate deprivation the carotenoid content of Euglena increased more than threefold. This increase was largely prevented by exposure of the cells to oxygen+carbon dioxide (95:5) during growth. Oxygenation appears to interfere with ring closure of the common carotenoid precursor. 5. Mitochondria obtained from Euglena exposed to oxygen during phosphate deprivation, i.e. when signs of oxygen toxicity were evident, had greatly decreased activities of succinate dehydrogenase, succinate-cytochrome c oxidoreductase and NADH cytochrome c oxidoreductase, compared with mitochondria obtained from Euglena exposed to oxygen in medium containing 20mm-phosphate. PMID- 4296329 TI - Enzymatic hydrolysis of sphingolipids. VII. Hydrolysis of gangliosides by a neuraminidase from calf brain. PMID- 4296328 TI - Quantitative analysis of simple lipid classes by thin-layer chromatography. PMID- 4296330 TI - Spin-labelled lipid-protein complexes. PMID- 4296331 TI - Glycolipids containing glucose and uronic acids in Pseudomonas species. PMID- 4296332 TI - Studies on sphingosines. XIV. On the phytosphingosine content of the major human kidney glycolipids. PMID- 4296333 TI - Alterations in the molecular species of rat liver lecithin by corn-oil feeding to essential fatty acid-deficient rats as a function of time. PMID- 4296334 TI - Effects in vitro and in vivo of synthetic phosphatidate phosphatase inhibitors. PMID- 4296335 TI - Phospholipids in tissues of the eye. I. Isolation, characterization and quantitative analysis by two-dimensional thin-layer chromatography of diacyl and vinyl-ether phospholipids. PMID- 4296336 TI - Phospholipids in the tissues of the eye. II. Composition and incorporation of 32Pi of phospholipids of normal rat and calf lens. PMID- 4296337 TI - Plasma angiotensinase activity in relation to the breakdown of phenylthiocarbamyl angiotensin II amide in hypertensive and normotensive patients. PMID- 4296338 TI - Blood angiotensinase activity in relation to the breakdown of angiotensin II amide and nonisotopic phenylthiocarbamyl-angiotensin II amide in hypertensive and normotensive patients. PMID- 4296339 TI - [Preparation of a hyperimmune sheep antiserum to B virus (Herpersvirus simiae) and its use for the early prevention of B virus infections]. PMID- 4296340 TI - [Hemagglutinin of Myxovirus parainfluenzae. V. Concentration of hemagglutinins type 1, 2 and 3 using organic solvents]. PMID- 4296341 TI - [Nosocomial infections caused by adenovirus type 3]. PMID- 4296342 TI - [Development of nonspecific reactivity in ontogenesis]. PMID- 4296343 TI - [Contribution to the study of the mechanism of hypoglycemia in fructose intolerance]. PMID- 4296344 TI - Origin of urinary enzymes hydrolysing beta-naphthylamides of L-leucine and L glutamic acid. PMID- 4296345 TI - The deposition of lipid and the composition of neutral lipids in the fat body of Sarcophaga bullata (Diptera). PMID- 4296346 TI - The carotenoid pigments of Daphnia magna Straus. I. The pigments of animals fed . Chlorella pyrenoidosa and pure carotenoids. PMID- 4296347 TI - Composition of plasma lipoproteins of the spiny dogfish Squalus acanthias. PMID- 4296348 TI - Nucleotide sequence homologies in nuclear and cytoplasmic ribonucleic acid from rat liver and hepatomas. PMID- 4296349 TI - A cytochemical comparison between the activity of lactic dehydrogenase diphosphopyridine nucleotide-diaphorase system in the testis and epididymis compared to some semen characteristics. PMID- 4296350 TI - Thin-layer chromatography of some trimethylsilylated carbohydrates. PMID- 4296351 TI - The effect of methoxy substitution and configuration on the thin-layer chromatographic behaviour of some closed E ring oxindole alkaloids. PMID- 4296352 TI - Tritium detection by beta-radioluminescence in standard media for thin-layer chromatography. PMID- 4296353 TI - [A method for the separation of testosterone and epitestosterone with silica gel thin layer chromatography]. PMID- 4296354 TI - Thin-layer chromatography and determination of thiamine salts, phosphoric esters, disulphides, and their respective thiochromes. PMID- 4296355 TI - Automatic chromatographic analysis of the dinitrophenylene and dinitrophennyl derivatives of lysine and tyrosine. PMID- 4296356 TI - Development and localization of virus-specific antigens during the multiplication of herpes simplex virus in BHK 21 cells. PMID- 4296357 TI - Analysis of molluscum-induced interference in mouse embryo cells: growth of encephalomyocarditis virus and dose-response relationships in molluscum-inhibited cultures. PMID- 4296358 TI - Recombination between conditional lethal mutants within a strain of foot-and mouth disease virus. PMID- 4296359 TI - Electron microscopy of poliovirus antigen antibody precipitates extracted from gel diffusion plates. PMID- 4296360 TI - The nucleic acid of Sendai virus and ribonucleic acid synthesis in cells infected by Sendai virus. PMID- 4296361 TI - Quantitative histochemical analysis of glycolytic intermediates and cofactors with an oil well technique. PMID- 4296362 TI - The site of ferricyanide reduction by reductases within mitochondria as studied by electron microscopy. PMID- 4296363 TI - Effect of 1-beta-D-arabinofuranosylcytosine on DNA synthesis. II. In rabbit kidney cells infected with herpes viruses. PMID- 4296364 TI - Glucose-6-phosphatase deficiency caused by radiation-induced alleles at the albino locus in the mouse. PMID- 4296365 TI - [Study of the adrenal function with betamethasone]. PMID- 4296366 TI - Epidemiologic features of trophoblastic disease. PMID- 4296367 TI - Hirsutism and benign androgenic hyperplasia of the adrenals. PMID- 4296368 TI - Giant nonfunctioning islet cell tumor. Survival after pancreaticoduodenectomy. PMID- 4296369 TI - Studies of the biosynthesis of polymyxin B. PMID- 4296370 TI - Interaction between colloidal montmorillonite and cells of Rhizobium species with different inogenic surfaces. PMID- 4296371 TI - Control of muscle glycogen phosphorylase activity by insulin. PMID- 4296372 TI - Activities of glycolytic enzymes during the early stages of differentiation in the cellular slime mold Dictyostelium discoideum. PMID- 4296373 TI - Two forms of copper (II) in fungal laccase. PMID- 4296374 TI - A comparative study of the regulation of nicotinamide-adenine dinucleotide biosynthesis. PMID- 4296375 TI - Mechanism of formation of sulphhaemoglobin. PMID- 4296376 TI - [Tissue culture atlases of brain tumors. 2. Glioblastoma, medulloblastoma, ependymoma and pinealoma]. PMID- 4296377 TI - Autonomic involvements in polyneuritis and its related disorders. PMID- 4296378 TI - [Von Recklinghausen's disease and brain tumors]. PMID- 4296379 TI - [Surgery of glioblastoma multiforme and its follow-up results]. PMID- 4296380 TI - Electron microscopic and biochemical characteristics of nuclei and nucleoli isolated from rat liver. AB - Rat liver nuclei were freed of cytoplasmic contamination by washing with Triton-X 100 and subsequent centrifugation through 2.2 M sucrose. Electron microscopic examination showed that the outer membranes of the nuclei had been removed, but that the nuclei otherwise resembled the nuclei of intact liver. Morphological studies, chemical estimations of DNA, RNA, and protein and the estimation of cytoplasmic "marker" enzymes suggested that contamination of nuclei by cytoplasmic components was limited. These nuclei were obtained in yields of about 70% and were suitable for the isolation of nucleoli. Nucleoli were isolated by the breaking of the nuclei by ultrasound and subsequent differential centrifugation. In ultrastructural appearance, the isolated nucleoli resembled nucleoli in intact tissue. However, at high magnifications the "granular" component of isolated nucleoli appeared to consist of tightly twisted fibers. The nucleoli could be obtained in yields of at least 30%, and the values for the chemical composition of the isolated nucleoli agreed with values previously reported. PMID- 4296381 TI - Distribution of phosphatases in the golgi region and associated structures of the thoracic ganglionic neurons in the grasshopper, Melanoplus differentialis. AB - The neuronal perikarya of the grasshopper contain sudanophilic lipochondria which exhibit an affinity for vital dyes. These lipochondria are membrane-delimited and display acid phosphatase activity; hence they correspond to lysosomes. Unlike those of most vertebrates, these lysosomes also hydrolyze thiamine pyrophosphate and adenosine triphosphate. Like vertebrate lysosomal "dense bodies," they are electron-opaque and contain granular, vesicular, or lamellar material. Along with several types of smaller dense bodies, they are found in close spatial association with the Golgi apparatus. The Golgi complexes are frequently arranged in concentric configurations within which these dense bodies lie. Some of the smaller dense bodies often lie close to or in association with the periphery of dense multivesicular bodies. Further, bodies occur that display gradations in structure between these multivesicular bodies and the dense lysosomes. Acid phosphatase activity is present in the small as well as the larger dense bodies, in the multivesicular bodies, and in some of the Golgi saccules, associated vesicles, and fenestrated membranes; thiamine pyrophosphatase is found in both the dense bodies and parts of the Golgi complex. The close spatial association of these organelles, together with their enzymatic similarities, suggests the existence of a functional or developmental relationship between them. PMID- 4296382 TI - Effect of prostaglandin E1 on the permeability response of the isolated collecting tubule to vasopressin, adenosine 3',5'-monophosphate, and theophylline. AB - The effect of prostaglandin E(1) (PGE(1)) on the water permeability response to vasopressin, theophylline, and cyclic adenosine 3',5'-monophosphate (C-AMP) of isolated, perfused collecting tubules of the rabbit was investigated in vitro. Prostaglandin is a naturally occurring substance present in a number of tissues, including kidney. It has been implicated in the action of a variety of hormones, many of which are known to exert their physiological effects through the intermediacy of the C-AMP system. In the collecting tubule, PGE(1) (10(-7) M) elicited a minimal increase in net water absorption along an osmotic gradient. However, when administered in association with a concentration of vasopressin (2.5 muU ml(-1)) selected to induce a submaximal increment in water absorption, the effect of the latter was reduced by approximately 50%. Theophylline (5 x 10( 3) M) also increased net water absorption, an effect not previously demonstrated in renal tissue. This effect was potentiated by the simulataneous addition of PGE(1). In contrast, PGE(1) did not influence the increase in net water absorption induced by C-AMP (10(-2) M). Since C-AMP is responsible for the permeability effects of vasopressin in renal tissue, the present results are consistent with the view that PGE(1) interferes with the action of the octapeptide by competing with it at a site which influences the generation of C AMP. In addition it is proposed that prostaglandin may be an important modulator of the action of vasopressin. The tubule is exquisitely sensitive to the hormone, responding to as little as 0.25 muU ml(-1). It is conceivable that in the intact animal prostaglandin may serve to dampen the effects of small amounts of residual hormone and thereby prevent overshoots in permeability which might otherwise occur. PMID- 4296383 TI - Late effect of estrogen on endotoxin response in the rat. PMID- 4296384 TI - Primary malignant osseous and soft tissue tumors. PMID- 4296385 TI - [Clinical asects of amyloidneuropathy]. PMID- 4296386 TI - [Neuropathy due to collagen diseases]. PMID- 4296387 TI - A concentrated psychiatric placement program: first six months' evaluation. PMID- 4296388 TI - Sperm-agglutinating autoantibodies in relation to male infertility. PMID- 4296389 TI - [Immediate and remote results of the treatment of Wilms' tumor in children]. PMID- 4296390 TI - [Anesthesia and specifications for the safety of operations in patients with infectious nonspecific (rheumatoid) polyarthritis and Bechterew disease]. PMID- 4296391 TI - [On phagocytic activity and some cytochemical changes in the leukocytes in rheumatism]. PMID- 4296392 TI - Cytopathologic changes of lymphatic tissues of cattle with the bovine virus diarrhea-mucosal disease complex. PMID- 4296393 TI - The release of noradrenaline by the sympathetic post-ganglionic nerves to the spleen of the cat in response to low frequency stimulation. PMID- 4296394 TI - [Changes in the hypertensive effects of angiotensin by adrenergic and anti adrenergic agents]. PMID- 4296395 TI - Eye signs in patients with Cushing's syndrome and pituitary tumors. PMID- 4296396 TI - Transient postictal hemianopsia. PMID- 4296397 TI - Some esterases of the pea (Pisum sativum L.). PMID- 4296398 TI - The inhibition of yeast alcohol dehydrogenase by 2-bromo-2-phenylacetaldehyde. PMID- 4296399 TI - Studies on the thyroidal UDPG pyrophosphorylase: partial purification and some of its properties. PMID- 4296400 TI - Studies on the ribonuclease activity of Proteus mirabilis. PMID- 4296401 TI - The non-specific nature of the nucleoside diphosphatase of rat liver microsomes. PMID- 4296402 TI - Purification and properties of ATP-sulphate adenylyltransferase from liver. PMID- 4296403 TI - [Treated case of temporal lobe tumor with pituitary adenoma associated with acromegaly]. PMID- 4296404 TI - [2 autopsied cases of eosinophilic pituitary adenoma followed by acute postoperative diabetes mellitus]. PMID- 4296405 TI - [Electroencephalography of closed head injury. 1. Incidence of its abnormality in the chronic stage]. PMID- 4296406 TI - Control of succinate oxidation by succinate-uptake by rat-liver mitochondria. PMID- 4296407 TI - The action of phospholipase A on the plasma membranes of rat liver cells. PMID- 4296408 TI - The phosphoinositide inositolphosphohydrolase of guinea-pig intestinal mucosa. PMID- 4296409 TI - Biological regulation of liver microsomal inorganic pyrophosphate-glucose phosphotransferase, glucose 6-phosphatase, and inorganic pyrophosphatase. Differential effects of fasting on synthetic and hydrolytic activities. PMID- 4296410 TI - Ribosomal change in liver after partial hepatectomy and acute stress. PMID- 4296411 TI - Purification and properties of a bovine adrenal 21-dehydrosteroid reductase. PMID- 4296412 TI - Spectrophotometric identification of an active site-specific acyl glyceraldehyde 3-phosphate dehydrogenase. The regulation of its kinetic and equilibrium properties by coenzyme. PMID- 4296414 TI - Food poisoning caused by heat-sensitive Clostridium welchii. A report of five recent outbreaks. PMID- 4296415 TI - The isolation and characterization of foot-and-mouth disease virus from clinically normal herds of cattle in Botswana. PMID- 4296416 TI - Lack of adaptation in lipogenesis by hepatoma 9121. AB - The "minimal deviation" hepatoma 9121, implanted in rats, was shown to biosynthesize fatty acids from acetate-1-(14)C at the same rate as normal rat liver but faster than host liver. Feeding the host animals a fat-deficient diet caused fatty acid biosynthesis to be increased 3- to 13-fold in liver, but the dietary regimen did not influence fatty acid biosynthesis in the tumor tissue. Oxygen consumption and the oxidation of acetate and mevalonate to CO(2) were all affected by the dietary manipulation in liver but not in hepatoma. The fat deficient diet decreased incorporation of acetate and mevalonate into cholesterol by the liver of control animals, increased it in the liver of host animals, and had no effect on this process in hepatoma. Thus, the transplantable tumor has lost the adaptive power of its parent tissue to respond to the dietary stimulus. The changes in fatty acid composition in total lipids in response to the fasting and refeeding were also markedly different in hepatoma from those in liver of the host animals. These results support the concept that this tumor is characterized by a loss of some metabolic controls. PMID- 4296417 TI - [Considerations and proposals on rickets prophylaxis]. PMID- 4296418 TI - The sarcomatous transformation of mammary carcinoma of mice in isologous transplantates, in cell culture, and in reimplantates. PMID- 4296419 TI - Tumour induction in the rat by a mixture of two non-carcinogenic aminoazo dyes. PMID- 4296420 TI - [The role of environment and heredity in the incidence of cancer and leukemia]. PMID- 4296421 TI - [Experimental hypertension]. PMID- 4296422 TI - [Diagnosis in nephrovascular hypertension]. PMID- 4296423 TI - [On synergetic relationships between nonspecific resistance increase and specific immunity (Experimental studies on foot-and-mouth disease (FMD) virus-infected mice)]. PMID- 4296424 TI - [On the diagnosis of solid adenoid ovarial tumors]. PMID- 4296425 TI - Recent experience with major hepatic resection. PMID- 4296426 TI - Occurrence of prostaglandin E2 in the human stomach, and a study of its effects on human isolated gastric muscle. PMID- 4296427 TI - Studies on the mode of action of clofibrate: effects on hormone-induced changes in plasma free fatty acids, cholesterol, phospholipids and total esterified fatty acids in rats and dogs. PMID- 4296428 TI - Plasma esterase and acid ribonuclease following the injection of heparin in dogs. PMID- 4296429 TI - [Circular and radial techniques in thin-layer chromatography]. PMID- 4296430 TI - [Thin-layer chromatography of fatty acids on silanized silica gel]. PMID- 4296431 TI - [Chromatographic properties of silica gel of different pore structures]. PMID- 4296432 TI - Separation of cholesterol esters. A comparison between paper and thin layer chromatography. PMID- 4296433 TI - Comparison of column, thin-layer and paper chromatography of oxidized alkyl oleates. PMID- 4296434 TI - [Thin-layer chromatographic determination of meso-inositol on ready-for-use plates]. PMID- 4296435 TI - Peripheral entrapment neuropathies. PMID- 4296436 TI - A method for the determination of plasma renin activity in small samples. PMID- 4296437 TI - [A fatal outcome after intravenous administration of triiotrast in urography]. PMID- 4296439 TI - Come down to earth and warm the soup. PMID- 4296438 TI - Inhibition of the phosphodiesterase activity of commercial E. coli phosphatase. PMID- 4296440 TI - Meeting "the increasing demand for the educated nurse". PMID- 4296441 TI - Granulosa-theca cell tumors. A clinical review of 102 patients. PMID- 4296442 TI - Gallamine (Flaxedil) and synaptic transmission in the spinal cord. AB - A paralyzing dose of gallamine (Flaxedil) (1 to 2 milligrams per kilogram of body weight) has no effect on synaptic transmission in the cat's spinal cord. In spinal cats ventilated with oxygen, we stimulated a dorsal spinal root and recorded the compound ventral root potential. The reflex potential was not affected by 6.25 milligrams of gallamine per kilogram. Giving 12.5 milligrams of gallamine per kilogram had no significant effect on the monosynaptic spike height, but the polysynaptic response rose briefly to 12 percent above control. Increased magnitude of the polysynaptic response appeared related to a concomitant rise in blood pressure. PMID- 4296443 TI - "Tactile" stimulus intensity: information transmission by relay neurons in different trigeminal nuclei. AB - Comparison of the information transmitted about the intensity of a steady "tactile" stimulus applied to facial skin by single trigemino-thalamic neurons in nucleus oralis and nucleus caudalis indicates that little information loss occurs at the medial lemniscal synaptic relay (nucleus oralis), but that it is gross within the nucleus caudalis. PMID- 4296444 TI - [Japanese encephalitis--past, present and future]. PMID- 4296445 TI - [Japanese encephalitis virus as a member of the arbovirus group]. PMID- 4296446 TI - [Mosquito vector of Japanese encephalitis virus--its ecology and physiology]. PMID- 4296447 TI - [Japanese encephalitis in animals]. PMID- 4296448 TI - [Electron microscopic studies of the Japanese encephalitis virus]. PMID- 4296449 TI - [Japanese encephalitis virus--variation of its antigen structure]. PMID- 4296450 TI - [Contribution of electron microscopy to the neuropathological study of Japanese encephalitis]. PMID- 4296451 TI - [Clinical aspects of Japanese encephalitis--with special reference to the authors' cases in the past 10 years]. PMID- 4296452 TI - [Electroencephalography of Japanese encephalitis]. PMID- 4296453 TI - [Virological and serological diagnosis of Japanese encephalitis]. PMID- 4296454 TI - [Treatment of Japanese encephalitis]. PMID- 4296455 TI - [Sequelae of Japanese encephalitis from the viewpoint of neuropsychiatry]. PMID- 4296457 TI - [Japanese encephalitis vaccine--its preparation, effect and evaluation]. PMID- 4296456 TI - [Neuropathology of Japanese encephalitis from the acute to chronic stage--with reference to its current status, etiology, relation to clinical features and orientation to future studies]. PMID- 4296458 TI - Neurologic disorders in renal failure. PMID- 4296459 TI - [Histo-enzymatic aspects of the rat liver after treatment with insulin]. PMID- 4296460 TI - [The histological description and taxonomy of anterior pituitary adenoma based on a study of about a hundred cases]. PMID- 4296461 TI - Accuracy and value of needle biopsy of the parotid gland. PMID- 4296463 TI - Pathologic quiz case 2. PMID- 4296462 TI - Hypoglycemia in Meniere's disease. PMID- 4296464 TI - The thymus and the pituitary-adrenal axis in anencephaly. A correlation between experimental foetal endocrinology and human pathological observations. PMID- 4296465 TI - Comparative studies of type 1 and type 2 & 'herpes simplex' viruses. PMID- 4296466 TI - [Diagnosis of chorionepithelioma and associated diseases of the trophoblast. General report on the material of the Research Center for Chorionepithelioma]. PMID- 4296467 TI - [Undesirable side effects of psychopharmaceuticals on the endocrine system]. PMID- 4296469 TI - [Remarks on the subject of tumors with the granular cells of Abrikosov]. PMID- 4296468 TI - [Considerations on diencephalic function in patients with psoriasis]. PMID- 4296470 TI - Enzymatic synthesis of glycerol 1-phosphate (D-alpha-glycerophosphate). Inorganic pyrophosphate-glycerol phosphotransferase and inorganic pyrophosphate-glucose phosphotransferase compared. PMID- 4296471 TI - Homocitrate formation in Neurospora crassa. Relation to lysine biosynthesis. PMID- 4296472 TI - General nature of "Wurster's blue shunts" in the respiratory chain. PMID- 4296473 TI - Erythritol metabolism by Propionibacterium pentosaceum. The over-all reaction sequence. PMID- 4296474 TI - Vitamin B 12 biosynthesis. Evidence for a new precursor vitamin B 12 5' phosphate. PMID- 4296475 TI - Relationship of injury to chemical carcinogenesis in the lungs of rats. PMID- 4296476 TI - Immunochemical studies on human lung cancer antigens soluble in 50 per cent saturated ammonium sulfate. PMID- 4296477 TI - Mechanism of induction of ovarian tumors in the mouse by 7,12 dimethylbenz[a]anthracene. 3. Tumor induction in organ culture. PMID- 4296478 TI - Hepatotoxic and carcinogenic effects of dimethylnitrosamine in low dosage. Light and electron microscopic study. PMID- 4296479 TI - Enhancing effect of a riboflavin analog on azo-dye carcinogenesis in rats. PMID- 4296480 TI - In vitro viral transformation of chemically transformed cells. PMID- 4296481 TI - [Electron microscopic observation on the effect of actinomycete Streptomyces punicens (viomycin) in the vestibular apparatus]. PMID- 4296482 TI - [Surgical treatment of congenital chest wall defect associated with congenital deformity of the hand]. PMID- 4296484 TI - [Typing of Cl. welchii. 2. Distribution of Cl. welchii types C and D in Hokkaido]. PMID- 4296483 TI - [Comparative studies on the blood pressure effect of alpha- and beta-Angiotensin II in intravenous infusions]. PMID- 4296485 TI - [Emergency respiratory resuscitation in acute trichloroethylene poisoning]. PMID- 4296486 TI - [Neurography]. PMID- 4296487 TI - [3 cases of synovial sarcoma]. PMID- 4296488 TI - [Case of hemangioma of the left knee joint]. PMID- 4296489 TI - Behaviour and morphology of pregnancy responsive mammary tumours in mice. PMID- 4296490 TI - [The activity of nucleases and acid adn alkaline phosphatases in renal tumors induced in rats by dimethylnitrosamine (histochemical study)]. PMID- 4296491 TI - Nephrotic syndrome in children. PMID- 4296492 TI - [Apropos of 10 intracranial hemorrhages occurring during anticoagulant treatments]. PMID- 4296493 TI - [Generalized infections by Candida albicans in children (apropos of 17 cases)]. PMID- 4296495 TI - [Study of a system of bibliographic documentation]. PMID- 4296494 TI - [Results obtained in epileptics by measurement of the temperature of the cerebrospinal fluid]. PMID- 4296496 TI - [Our experience with new antibiotics in pediatrics]. PMID- 4296497 TI - [Dynamic study of the urinary excretion of electrolytes in arterial hypertension]. PMID- 4296498 TI - [Cardiac manifestations associated with Steinert's disease. (Apropos of 10 cases)]. PMID- 4296499 TI - [Cystic degeneration of the adventitia of the popliteal artery. Apropos of a further case]. PMID- 4296500 TI - [Clinical and cytologic study of a 2nd case of xanthomatous IgA myeloma with circulating anti-lipoprotein antibodies]. PMID- 4296501 TI - [Central nervous system hemorrhages associated with acute leukemia. (Apropos of a rare localization revealing the disease)]. PMID- 4296502 TI - [Digestive "breakdowns"]. PMID- 4296503 TI - Chacko-Nair egg-enriched selective medium in the diagnosis of pathogenic Neisseriae. PMID- 4296505 TI - VI. Chemical transmission at the neuromuscular junction: concepts and consequences. PMID- 4296504 TI - Norethisterone jaundice in two sisters. PMID- 4296506 TI - 3. Interaction of psychotropic drugs with agents employed in clinical anesthesia. PMID- 4296507 TI - Cultivation of fused cells resulting from treatment of cells with HVJ. II. Division of binucleated cells resulting from fusion of two KB cells by HVJ. PMID- 4296508 TI - The effect of cortisone on glucose-6-phosphatase during development. PMID- 4296509 TI - The binding of DNA to residual protein in mammalian nuclei. PMID- 4296510 TI - Studies with carcinogens and tumor-promoting agents in cell culture. PMID- 4296511 TI - Selective effects of L-fucose on BHK21 hamster fibroblasts and on BHK21 cells transformed by infections with polyoma virus. PMID- 4296512 TI - Nuclear fraction of Bacillus subtilis as a template for ribonucleic acid synthesis. AB - A "nuclear fraction" prepared from Bacillus subtilis was a more efficient template than purified deoxyribonucleic acid for the synthesis of ribonucleic acid by exogenously added ribonucleic acid polymerase isolated from B. subtilis. The initial rate of synthesis with the nuclear fraction was higher and synthesis continued for several hours, yielding an amount of ribonucleic acid greater than the amount of deoxyribonucleic acid used as the template. The product was heterogenous in size, with a large portion exceeding 23S. When purified deoxyribonucleic acid was the template, a more limited synthesis was observed with a predominantly 7S product. However, the ribonucleic acids produced in vitro from these templates were very similar to each other and to in vivo synthesized ribonucleic acid as determined by the competition of ribonucleic acid from whole cells in the annealing of in vitro synthesized ribonucleic acids to deoxyribonucleic acid. Treatment of the nuclear fraction with heat (60 C for 15 min) or trypsin reduced the capacity of the nuclear fraction to synthesize ribonucleic acid to the level observed with purified deoxyribonucleic acid. PMID- 4296513 TI - Initiation of bacterial spore germination. AB - To investigate the problem of initiation in bacterial spore germination, we isolated, from extracts of dormant spores of Bacillus cereus strain T and B. licheniformis, a protein that initiated spore germination when added to a suspension of heat-activated spores. The optimal conditions for initiatory activity of this protein (the initiator) were 30 C in 0.01 to 0.04 m NaCl and 0.01 m tris(hydroxymethyl)aminomethane (pH 8.5). The initiator was inhibited by phosphate but required two co-factors, l-alanine (1/7 of K(m) for l-alanine inhibited germination) and nicotinamide adenine dinucleotide (1.25 x 10(-4)m). In the crude extract, the initiator activity was increased 3.5-fold by heating the extract at 65 C for 10 min, but the partially purified initiator preparation was completely heat-sensitive (65 C for 5 min). Heat stability could be conferred on the purified initiator by adding 10(-3)m dipicolinic acid. A fractionation of this protein that excluded l-alanine dehydrogenase and adenosine deaminase from the initiator activity was developed. The molecular weight of the initiator was estimated as 7 x 10(4). The kinetics of germination in the presence of initiator were examined at various concentrations of l-alanine and nicotinamide adenine dinucleotide. PMID- 4296514 TI - K+-stimulated phosphatase of microsomes from gastric mucosa. PMID- 4296515 TI - The relation of karyotypic change to loss of contact inhibition of division in human diploid cells after SV40 infection. PMID- 4296516 TI - Studies on carcinogenesis by avian sarcoma viruses. VI. Differential multiplication of uninfected and of converted cells in response to insulin. PMID- 4296517 TI - The interaction of closed circular DNA with intercalative dyes. I. The superhelix density of SV40 DNA in the presence and absence of dye. PMID- 4296518 TI - Early and late helix-coil transitions in closed circular DNA. The number of superhelical turns in polyoma DNA. PMID- 4296519 TI - [2 rare cases of malignant synovioma]. PMID- 4296520 TI - [Remote results of the surgical treatment of cancer of the stomach]. PMID- 4296521 TI - Pathophysiology of hypertension. PMID- 4296522 TI - [On 2 cases of vulvar hidradenoma]. PMID- 4296523 TI - [Technic for the cytochemical diagnosis of endometrial carcinoma]. PMID- 4296524 TI - Renal-pressor hypertension secondary to unilateral hydronephrosis. PMID- 4296525 TI - Association of cytomegalovirus infection with the postperfusion syndrome. PMID- 4296526 TI - [Preventive effect of exogenous interferon in cultures of chick embryo fibroblasts following x-irradiation]. PMID- 4296527 TI - The influence of L-thyroxine on the metabolism of ethanol in rat liver. PMID- 4296528 TI - Bioassay of prolonged corticotropin preparations, with the international working standard on living guinea pigs. PMID- 4296529 TI - Experimental studies on continuous or intermittent selective brain cooling by means of carotico-carotid shunt in dogs, especially on the application of polarographic measurement in the prevention of cerebral anoxia. PMID- 4296530 TI - [On lymphepithelioma in childhood. (Lymphopithelioma complicated by generalized cytomegalic inclusion disease)]. PMID- 4296531 TI - [On embryonal malignant hepatoma in early childhood]. PMID- 4296532 TI - [Report on the characteristics of foot-and-mouth disease virus capable of being used as live vaccines]. PMID- 4296533 TI - [Study of the preservation of infectious ribonucleic acid extracted from foot-and mouth disease virus]. PMID- 4296534 TI - Interference in modified foot-and-mouth disease viruses. PMID- 4296535 TI - An early stage in the comparison of methods of modification of a field strain of foot-and-mouth disease, type A (Turkey 19-64). PMID- 4296536 TI - [Survival in cattle of the modified foot-and-mouth disease virus]. PMID- 4296537 TI - Typing of the foot-and-mouth disease virus. Result of diagnosis and typing of foot-and-mouth disease virus. PMID- 4296538 TI - Left ventricular function in children studied by increasing peripheral resistance with angiotensin. PMID- 4296539 TI - [Clinico-radiological and neuropsychiatric findings in a group of prematures examined years later]. PMID- 4296540 TI - [On the behavior of erythrocytic enzymes after administration of amino acids in vitro]. PMID- 4296541 TI - [Clinical contribution to the study of malignant tumors of the kidney in childhood]. PMID- 4296542 TI - [On 3 cases of gomus tumor of the extremities. (Clinical contribution)]. PMID- 4296543 TI - An extra-adrenal response to sodium loading revealed by thymectomy. PMID- 4296544 TI - Recent developments in the therapy of gout. PMID- 4296545 TI - [Restorative surgery in childhood]. PMID- 4296546 TI - [Current clinical and therapeutic problems in multiple sclerosis]. PMID- 4296547 TI - [Immuno-virological research on an epidemic of acute diseases of the respiratory tract with viral etiology in premature infants. Myxovirus of the parainfluenza type 3 of hemadsorbent virus type 1]. PMID- 4296548 TI - [Multiple malignant neoplasms in the same patient]. PMID- 4296549 TI - [Tuberous sclerosis and intraventricular tumors]. PMID- 4296550 TI - [Considerations on 3 cases of association of intracranial aneurysm and tumors]. PMID- 4296551 TI - [Clinical experience in the use of interferonogen in the treatment of adenoviral and herpetic lesions of the eye]. PMID- 4296552 TI - [Interferon, inducers of its formation -- interferonogens and prospects of their use in viral diseases of the eye (literature survey)]. PMID- 4296553 TI - [Congenital absence of the thumb]. PMID- 4296555 TI - Plasma renin activity after bleeding in rats with transected or destroyed medulla spinalis. PMID- 4296554 TI - [Concentration of nucleotides and other acid-soluble P compounds in the rat blood during erythrocyte maturing and aging]. PMID- 4296556 TI - Studies on cell-reaction of the nasal epithelium during the fusion to palatine shelves. PMID- 4296557 TI - [Secretion in vitro of hyaluronic acid and of collagen by transformed human embryonic cells in culture by Rous sarcoma virus]. PMID- 4296558 TI - [Determination of luteinizing hormone (LH) based on its action in vitro in the biosynthesis of progesterone]. PMID- 4296559 TI - [Biologic activity of human interferon on the simian species in vitro and in vivo]. PMID- 4296560 TI - [Estrogen-producing ovarian tumors]. PMID- 4296561 TI - [Clinical studies on ACTH in the blood. II. Effects of SU-4885 and stress on ACTH in the blood and its diural variations]. PMID- 4296562 TI - [Clinical studies on ACTH in the blood. 3. Fate of exogenous ACTH in the blood measured by immuoassay and bioassay]. PMID- 4296563 TI - [Patterns of adrenal steroids present in the blood]. PMID- 4296564 TI - [Pituitary hormones]. PMID- 4296565 TI - [Blood corticotropin levels and synthesis and release of corticotropin in adrenal failure]. PMID- 4296566 TI - [Clinical studies of ACTH. 1. Extra-adrenal effect of ACTH on cortisol metabolism]. PMID- 4296567 TI - [Response to the administration of ACTH in young, old and pregnant women]. PMID- 4296568 TI - [Histamine metabolism via histamine nucleotides]. PMID- 4296569 TI - [Effect of lidocaine on ganglionic transmission]. PMID- 4296571 TI - [Studies on liver metabolism in phosphatic diabetes]. PMID- 4296573 TI - [Nil nocere. Neurologic complications of anticoagulant therapy]. PMID- 4296572 TI - Correlation of transmitter release with membrane properties of the presynaptic fiber of the squid giant synapse. AB - Depolarization of the presynaptic terminal by current produced a postsynaptic potential (PSP) which increased with increasing presynaptic polarization and then reached a plateau. Iontophoretic injection of tetraethylammonium ions (TEA) into the presynaptic axon near the terminal produced a prolonged presynaptic spike. The resulting PSP is increased in size and its time course closely followed that of the presynaptic spike. The presynaptic fiber no longer exhibited rectification and strong depolarizations revealed that the PSP reached a maximum with about 110 mv depolarization. Further depolarization produced a decrease in PSP amplitude and finally transmission was blocked. However, a PSP then always appeared on withdrawal of the depolarizing current. Under the conditions of these experiments, the PSP could be considered a direct measure of transmitter release. Bathing the TEA-injected synapse with concentrations of tetrodotoxin (TTX) sufficient to block spike activity in both pre- and postsynaptic axons did not greatly modify postsynaptic electrogenesis. However, doubling TTX concentration reversibly blocked PSP. Thus the permeability changes to Na and K accompanying the spike do not appear necessary for transmitter release. Some other processes related to the level of presynaptic polarization must be involved to explain the data. The inhibition of transmitter release by strong depolarizations appears to be related to Ca action. A membrane Ca current may also be necessary for normal transmitter release. PMID- 4296574 TI - [On the immunology of histones from rat hepatoma and normal rat liver]. PMID- 4296575 TI - [Cytometric studies on tumor cells following 5-fluorouracil treatment]. PMID- 4296576 TI - Transmission of somatic sensory volleys through ascending spinal hindlimb pathways during sleep and wakefulness. PMID- 4296577 TI - [The elimination of hardly soluble dust particles from the respiratory zone of the lungs (alveolar cleansing)]. PMID- 4296578 TI - [Pulmonary elimination of insoluble particles]. PMID- 4296579 TI - [Experimental studies on the pulmonary elimination of radioactive aerosols using profile scanning and total body counting]. PMID- 4296580 TI - [Experimental study of the elimination of dust from the lungs. VI. Effect of acute inflammation produced by diazomethane on the pulmonary distribution and elimination of quartz dust in rabbits]. PMID- 4296581 TI - Effects of angiotensin and noradrenaline on flow and composition of the renal lymph. PMID- 4296582 TI - [Effect of changes in the sodium concentration in the suspension medium and of strophanthin on the oxygen absorption of isolated rat kidney cells]. PMID- 4296583 TI - [Contamination of the population with adenovirus type 18, cancerogenic in animal experiments]. PMID- 4296585 TI - [Multiplication of poliomyelitis viruses in human leukocyte cultures]. PMID- 4296584 TI - [Studies on the biochemical differentiation of Mycoplasma]. PMID- 4296586 TI - [Linitis plastica]. PMID- 4296587 TI - [Simplified management and after care of genu valgum]. PMID- 4296588 TI - [On the diagnosis of islet-cell adenoma using visceral angiography]. PMID- 4296589 TI - [Proliferation of the endometrium and vaginal epithelium through conjugated estrogens]. PMID- 4296590 TI - The lectins of some Polish plants. IV. Effect of sodium periodate. PMID- 4296591 TI - [Hormone therapy of aplastic anemia]. PMID- 4296592 TI - [Malate dehydrogenase of Aspergillus niger]. PMID- 4296593 TI - [Conformational changes in lactic dehydrogenase under inhibition]. PMID- 4296594 TI - [Specificity of snake venom phosphodiesterases to phosphodiester bonds formed by minor ribonucleotides]. PMID- 4296595 TI - [On the action of muscle relaxants under conditions of modified immunogenic reactivity of the body]. PMID- 4296596 TI - [Extramitochondrial oxidation in liver cells and in hepatoma]. PMID- 4296597 TI - [Electromyographic studies in the diagnosis of latent neuropathy in chronic alcoholism]. PMID- 4296598 TI - [Clinical trials of a new water-soluble contrast medium: sodium, calcium and magnesium metrizoate]. PMID- 4296599 TI - Krukenberg tumour primary in the jejunum. A case report. PMID- 4296600 TI - [Absence of favorable effects of pressor agents on cardiac output and peripheral circulatory flow in advanced shock]. PMID- 4296601 TI - [Results of adrenal exploration in 70 cases of hemochromatosis using the Thorn test (with urinary steroid determination)]. PMID- 4296602 TI - [Median values and limits of normality of bone age in children aged 9 months to 12 years in Sao Paulo]. PMID- 4296603 TI - Mechanisms of interaction between a phosphoinositide anticoagulant and a phospholipid activator in the Stypven type conversion of prothrombin to thrombin. PMID- 4296604 TI - [On the behavior of some enzymes in the fetal adrenal glands of cattle]. PMID- 4296605 TI - [Changes of cerebral bioelectric activity induced by carotid angiography in intracranial expansive processes]. PMID- 4296606 TI - [The 2,3-diphosphoglycerate and glucose-1,6-diphosphate content of the red cell: technics of determination]. PMID- 4296607 TI - Branchial cleft remnants suggesting tuberculous lymphadenitis. PMID- 4296608 TI - Multicentric reticulohistiocytosis. Report of a case with histochemical studies. PMID- 4296609 TI - Erythema elevatum diutinum. PMID- 4296610 TI - Extramammary Paget's disease. PMID- 4296611 TI - [Enzymes of energy producing metabolism in nevus cells. A histochemical study]. PMID- 4296613 TI - [Contribution to the study of comedocarcinoma of the breast]. PMID- 4296614 TI - Some biophysical properties of a vibriophage and its DNA. PMID- 4296612 TI - [The Langerhans cells. Results of newer experimental studies. II]. PMID- 4296615 TI - Phenethyl alcohol: reversible inhibition of synthesis of macromolecules and disaggregation of polysomes in rat hepatoma cells. PMID- 4296616 TI - Cooperative study on cardiac catheterization. Complications involving the nervous system. PMID- 4296617 TI - Cooperative study on cardiac catheterization. Summary. PMID- 4296618 TI - [Metabolic regulation of thyroid hormone--tetraiodothyroacetic acid]. PMID- 4296619 TI - [Casuistic contribution to the study of viral encephalopathies]. PMID- 4296620 TI - Immunochemical study of beta-corticotropin-(1-24)-tetracosa-peptide. PMID- 4296621 TI - [Histopochemistry of some enzyme activities of glucide metabolism in the normal and pathological human vulvar epithelium]. PMID- 4296622 TI - [The effect of Natulan on energy metabolism]. PMID- 4296623 TI - [Comparative electron microscopy studies of normal human pancreas islands and a hormonally-active islet cell carcinoma with hyperinsulinism]. PMID- 4296624 TI - [On transient spinal ischemia in arteriosclerotic disease of the bifurcation of the aorta with various degrees of its chronic occlusion]. PMID- 4296625 TI - Experimental studies in mice on the late effects of radioactive and nonradioactive contrast media. PMID- 4296626 TI - [Excretion of pregnanediol and pregnenolone in the urine of newborn infants. Stimulation through chorinc gonadotropin and ACTH]. PMID- 4296627 TI - [The problem of inclusion bodies in tumors. I. Animals]. PMID- 4296628 TI - [Embryonal sarcoma. Histochemical and histoenzymatic study of 6 cases]. PMID- 4296629 TI - [Soft tissue sarcomas (experience of the Institut Jules Bordet]. PMID- 4296630 TI - [Tansformation, in gelatinized media, of a diploid strain of human embryonic cells by Rous virus (Schmidt-Ruppin strain)]. PMID- 4296631 TI - [Chemotherapy and chemoprophylaxis of surgical infections]. PMID- 4296632 TI - [Nuclear volume determinations in liver, adrenal gland and thyroid gland following experimental changes in the anterior pituitary-thyroid gland system]. PMID- 4296633 TI - [Adrenal hirsutism (3beta-hydroxysteroid dehydrogenase deficiency). Studies using a chromatographic separation of the 17-ketosteroid fraction in the urine. 1. Dehydroepiandrosterone-forming adrenocortical adenoma]. PMID- 4296634 TI - [On the enzymatic activity of the adrenal cortex during functional changes in the anterior pituitary-thyroid gland system]. PMID- 4296635 TI - The active sequence in the ACTH molecule responsible for inhibition of the extinction of conditioned avoidance behaviour in rats. PMID- 4296636 TI - Hypersensitivity olipid mobilizing agents in essential fatty acid (EFA) deficient rats. PMID- 4296637 TI - [Plasmatic adrenocorticotropin activity in patients treated with ultrasonic therapy of the pituitary gland according to the Arslan method]. PMID- 4296638 TI - [Early histochemical enzyme changes in the experimental myocardial infarct of rats]. PMID- 4296640 TI - [Alteration of the tuberculin reaction by microbial polysaccharide]. PMID- 4296639 TI - [Isolation and differeniation of adenovirus type 8 in epidemic keratoconjunctivitis in Leipzig]. PMID- 4296641 TI - [Enzymatic synthesis of (5-3H)D-fructose-1,6-bisphosphate, (5-3H)D-fructose-6 phosphate, (5-3H)D-glucose-6-phosphate and (5-3H)D-glucose]. PMID- 4296642 TI - [Comparative ESR studies on the iron-containing active center of lant ferredoxin and xanthine oxidase]. PMID- 4296643 TI - E.S.R. spectra of free radicals induced in nucleic acid purine and pyrimidine bases and selected analogues by exposure to hydrogen atoms. PMID- 4296644 TI - Effects of whole-body irradiation and radio-mimetic chemicals on the acid RNAse and phosphodiesterase levels of rat intestinal homogenate. PMID- 4296645 TI - Quantitative thin-layer chromatography of trimethylsilyl ethers of hydroxylic steroids. PMID- 4296646 TI - The effect of methoxy substitution and of configuration on the thin-layer chromatographic behaviour of some heteroyohimbine alkaloids. PMID- 4296647 TI - Chromatography of beta-carbolines. PMID- 4296648 TI - Concerning thin-layer electrophoresis of carbohydrates. PMID- 4296649 TI - Detection of rearrangement reactions by silver nitrate thin-layer chromatography. PMID- 4296650 TI - Standardization of aqueous silicic acid for thin-layer chromatography. PMID- 4296651 TI - A screening technique for indian hemp (Cannabis sativa L.). PMID- 4296652 TI - The separation of ten tobacco alkaloids by thin-layer chromatography. PMID- 4296653 TI - Separation of the pyridine-monocarboxylic and 2-pyridine-dicarboxylic acids by two-dimensional ion-exchange thin-layer chromatography. PMID- 4296654 TI - Identification of the nitrate esters of five alkyl alcohols by thin-layer chromatography. PMID- 4296655 TI - [Separation of mono-, di-, and triphosphate nucleosides by thin layer chromatography on silica]. PMID- 4296656 TI - XIX. Paper chromatographic identification of sphingomyelins and their N-acyl derivatives. PMID- 4296657 TI - Biochemistry of sphingolipids. XX. Chromatographic identification of the erythro configuration of sphingosine bases isolated from human brain sphingomyelins. PMID- 4296658 TI - [New technic of radiooculography with Methiodal with simultaneous anesthesia and injection of the contrast medium]. PMID- 4296659 TI - Effects of furosemide uring antidiuresis and antinatriuresis induced by angiotensin. PMID- 4296660 TI - [Role of the kidney in the metabolism of protein hormones]. PMID- 4296661 TI - [Quantitative histochemistry of the human nephron]. PMID- 4296662 TI - [Enzymatic anomalies and human nephropathies]. PMID- 4296663 TI - NMR spectroscopy of methyl derivatives of galactose. PMID- 4296664 TI - On the possible involvement of charge transfer complexes (redox systems) in radioprotection. PMID- 4296665 TI - [On the nature of kinin hormones]. PMID- 4296666 TI - [Moadon in the management of child seizures]. PMID- 4296667 TI - [Clinical aspects of hypopituitarism]. PMID- 4296668 TI - [On the development of the cardiac muscle and conductive system muscle of the rat and the guinea pig. Histological, histochemical and electrophysiological studies]. PMID- 4296669 TI - [Results of late examination following elbow joint dislocations]. PMID- 4296670 TI - Prerequisites for the natriuretic effect of val-5-angiotensin II amide in the rat. PMID- 4296671 TI - Metabolic adaptations to chronic heat exposure in the golden hamster. PMID- 4296672 TI - Effect of hormones on ceruloplasmin and copper concentrations in the plasma of the rat. PMID- 4296673 TI - Acid-base behavior of separated canine renal tubule cells. PMID- 4296674 TI - Steroidogenic response in normal dogs receiving blood from dogs with caval constriction. PMID- 4296675 TI - Antibody patterns of parainfluenza viruses in human populations on Taiwan. PMID- 4296676 TI - Fractionation of Bacillus subtilis DNA by use of poly-L-lysine kieselguhr columns. PMID- 4296677 TI - Deaminase activity of commercial spleen phosphodiesterase. PMID- 4296678 TI - Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics. PMID- 4296679 TI - Gradation of specificity with regard to sugar among nucleases. PMID- 4296680 TI - Selenium as an acid labile sulfur replacement in putidaredoxin. PMID- 4296681 TI - Carcinoma of the breast. Histologic and clinical features of apocrine tumors. PMID- 4296682 TI - Alteration in liver lipid and lipid fatty acid composition after partial hepatectomy in the rat. PMID- 4296684 TI - Studies on nucleolar 4 to 6 S ribonucleic acid of Novikoff hepatoma cells. PMID- 4296683 TI - Natural activators for liver fructose 1,6-diphosphatase and the reversal of adenosine 5'-monophosphate inhibition by muscle phosphofructokinase. PMID- 4296685 TI - Control of glycogenolysis in the toad's urinary bladder. The effect of anaerobiosis, sodium transport, and arginine vasotocin. PMID- 4296687 TI - Chemistry and metabolism of 3-deoxy-D-mannooctulosonic acid. I. Stereochemical determination. PMID- 4296686 TI - Release of prostaglandin from rat epididymal fat pad on nervous and hormonal stimulation. PMID- 4296688 TI - Rapid labeling of mitochondrial lipids by labeled orthophosphate and adenosine triphosphate. PMID- 4296689 TI - Acyl dihydroxyacetone phosphate. Characterization of a 32P-labeled lipid from guinea pig liver mitochondria. PMID- 4296690 TI - Respiratory processes in brown adipose tissue. PMID- 4296691 TI - Neonatal infection caused by adenovirus type 7. PMID- 4296692 TI - A search for the reservoir of cytomegalovirus in salivary gland tissue. PMID- 4296693 TI - The incidence of cytomegaloviruria and postmortem cytomegalic inclusions in children with acute leukemia. PMID- 4296694 TI - Effect of exogenous dopamine on rat adrenal ascorbic acid. PMID- 4296695 TI - Studies on the radiocalcium uptake and the adenosine triphosphatases of skeletal and cardiac sarcoplasmic reticulum fractions (SRF). PMID- 4296696 TI - Mechanism of action of norepinephrine in eliciting an eating response on injection into the rat hypothalamus. PMID- 4296697 TI - Blood flow and free fatty acid release from the epigastric adipose tissue of rabbits. PMID- 4296698 TI - A dual effect of calcium ions on neuromuscular facilitation. AB - 1. The changes in neuromuscular facilitation produced by varying extracellular calcium and magnesium concentrations have been studied at the frog neuromuscular junction using intracellular recording and automatic averaging of responses.2. When [Ca] was elevated three effects were observed: a large increase in transmitter release by the first impulse; a decrease in facilitation at short intervals between impulses; and a prolongation of the time course of the facilitated release. If the release by the first impulse is kept at constant level, by raising both [Ca] and [Mg], facilitation becomes greater at all impulse intervals.3. The results have been discussed in terms of the hypothesis that the action of calcium is responsible for neuromuscular facilitation. PMID- 4296699 TI - The role of calcium in neuromuscular facilitation. AB - 1. The hypothesis is put forward that a residue of the ;active calcium' which enters the terminal axon membrane during the nerve impulse is responsible for short-term facilitation.2. This suggestion has been tested on the myoneural junction by varying the local calcium concentration so that during the first of two nerve impulses [Ca](o) is either much lower than, or raised to a level approaching that, during the second impulse. Facilitation is much larger in the latter case, which is in accordance with the ;calcium hypothesis'.3. A short pulse of depolarization focally applied to the junction is followed by a brief period of very intense facilitation. This can be seen in the tetrodotoxin-treated preparation, e.g. by lengthening the depolarization from 1 to 2 msec which can cause a more than fifty-fold increase in transmitter release. This large ;early facilitation' (which presumably occurs also during the course of a normal action potential) is discussed in relation to the ;calcium hypothesis'. PMID- 4296700 TI - Prolonged remissions in acute myelocytic leukemia in adults. PMID- 4296701 TI - Combined liver-kidney isotope scans. Diagnosis of abdominal masses in children. PMID- 4296702 TI - [Phosphotransacetylase and the biogenic inhibiting material of acetate activation in respect to the acetylphosphatase in leeches (Hirudo medicinalis)]. PMID- 4296703 TI - [The Rous sarcoma virus (R.S.V.); its defectivity and viral oncogenesis]. PMID- 4296704 TI - [Retrograde jugulography for jugular glomangiomas of the middle ear]. PMID- 4296705 TI - [On the problem of the effect of ACTH and corticosteroids on the course of chickenpox]. PMID- 4296706 TI - [Behavior of some enzymes and metabolites in the erythrocytes of normal subjects]. PMID- 4296707 TI - Toxoplasma gondii and cytomegalovirus: mixed infection by a parasite and a virus. AB - Human fibroblasts infected in vitro with cytomegalovirus are relatively resistant to infection by Toxoplasma gondii during the first 4 days of virus infection. After 5 days, however, the cytomegalovirus-infected cells become susceptible to the parasites. The toxoplasmas replicate in paracentral rosettes surrounded by host cell mitochondria. This growth configuration differs from that seen in human fibroblasts infected in vitro with toxoplasma only but resembles the pattern seen in doubly infected cells found in human necropsy tissue. PMID- 4296708 TI - [On the submicroscopic structure of gram negative pathogenic bacteria]. PMID- 4296709 TI - Stellate ganglionic transmission and myocardial contractile force during halothane anesthesia. PMID- 4296710 TI - Plasma levels of ACTH and cortisol in man during diethyl ether anesthesia and surgery. PMID- 4296711 TI - Induction of an inhibitor of influenza virus hemagglutination by treatment of serum with periodate. AB - Serum is commonly treated with potassium periodate to destroy nonspecific inhibitors of influenza virus hemagglutination. We have observed, however, that such treatment of serum without pre-existing inhibitor produced high titers of inhibitor against certain strains of influenza virus. Inhibitor was induced in the serum from several different animal species but not in hamster or mouse serum. Periodate treatment of serum albumin, fraction V, from several animals, including man, creates this inhibitor. Our data indicate that the inhibitor induced in the serum of various animal species differs in its mechanism of induction and in its resistance to receptor-destroying enzyme and trypsin. Hemagglutination by B/Singapore/3/64, B/Colorado/2/65, B/Georgia/1/65, and B/Massachusetts/3/66 strains of influenza virus is inhibited by periodate-treated human serum at dilutions as high as 1:5,120. The routine use of periodate treatment of serum in diagnostic and surveillance studies of influenza virus infections is not recommended. PMID- 4296712 TI - Hyperinsulinism. Surgical results and management of occult functioning islet cell tumor: review of 154 cases. PMID- 4296713 TI - Effects of bilateral adrenalectomy and continuous light on the circadian rhythm of corticotropin in female rats. PMID- 4296714 TI - Effects of cortisone on renal sodium excretion in rabbits. PMID- 4296715 TI - Fibrinoid necrosis of placental villi. PMID- 4296716 TI - Orf. Report of 19 human cases with clinical and pathological observations. PMID- 4296717 TI - The pathology of renal cancer. PMID- 4296718 TI - The unique association between salivary gland cancer and breast cancer. PMID- 4296720 TI - Electromyography in collagen disease. PMID- 4296719 TI - Antihypertensive actions of diuretics. Comparative study of an aldosterone antagonist and a thiazide, alone and together. PMID- 4296721 TI - Intestinal alkaline phosphatase activity in familial hypophosphatasia. PMID- 4296722 TI - Neuroendocrine reactions and the radiation-induced variations in rat intestinal alkaline ribonuclease levels. PMID- 4296723 TI - ESR studies of spin transfer in irradiated nucleic acid--cysteamine systems. PMID- 4296724 TI - Agent of disease contracted from green monkeys. AB - An infectious agent obtained from patients who became ill after exposure to tissues of African green monkeys is viral in character. By electron microscopy, the agent appeared cylindrical, 90 to 100 nanometers in diameter, and 130 to 2600 nanometers in length. Cross-striations at 5-nanometer intervals and a core diameter of 45 nanometers were observed. The agent was completely resistant to the effects of the metabolic inhibitor 5-bromodeoxyuridine, which may mean that RNA is the genetic material. It was sensitive to ether and relatively sensitive to destruction by heat. PMID- 4296725 TI - Discussion of the natural history of vesicular stomatitis. PMID- 4296726 TI - Genetic changes in attenuated poliovirus strains cultivated on human intestine in vitro. PMID- 4296727 TI - Serodifferentiation of type 3 poliovirus strains isolated 1960-1965 from patients and healthy vaccinees. Characterization of strains associated with disease in vaccinated persons and household contacts. PMID- 4296728 TI - The safety of human diploid cell strains for man: a controlled study of symptoms occurring after the administration of WM-3 living attenuated poliovirus vaccine prepared in the WI-38 human diploid cell strain. PMID- 4296729 TI - Viruses and disease. II. An outbreak of parainfluenza Type 2 in a children's home. PMID- 4296730 TI - Rhinovirus infections in a student population: isolation of five new serotypes. PMID- 4296731 TI - Public health nursing in California State Hospitals for the mentally retarded. PMID- 4296732 TI - Pathology of vestibular disorders vertigo of peripheral origin: histopathology. PMID- 4296733 TI - Official statement. The Doman-Delacato treatment of neurologically handicapped children. PMID- 4296734 TI - Gas gangrene in abdominal surgery. PMID- 4296735 TI - The influence of cortisol and adrenocorticotropic hormone on the sedimentation rate of the red blood cells. PMID- 4296736 TI - The incidence of buccal pigmentation in caucasoids and negroids in Britain. PMID- 4296737 TI - Oral herpetic infection in adults. Clinical, histological and cytological features. PMID- 4296738 TI - Multiple granular-cell myoblastoma (schwannoma) in a child. PMID- 4296739 TI - Some electrophysiological methods for studying the action of narcotic agents in animals, with special reference to industrial solvents: a review. PMID- 4296740 TI - Adenomatoid ameloblastoma. An analysis of nine cases by histopathological and electron microscopic study. PMID- 4296741 TI - Studies on infectious mononucleosis. 3. Clinical data, serologic and epidemiologic findings. PMID- 4296742 TI - Inflammatory pseudotumors of the stomach. Follow-up report and correction. PMID- 4296743 TI - Ultrastructure of myoepithelial cells in human mammary gland tumors. PMID- 4296744 TI - Embryonic ependymoma arising in a cerebral hemisphere. PMID- 4296745 TI - Embryonal rhabdomyosarcoma. An ultrastructural study. PMID- 4296746 TI - Cystosarcoma phylloides. An ultrastructural study. PMID- 4296747 TI - Malignant mixed tumors of the major salivary glands. Special reference to the histologic structure in metastases. PMID- 4296748 TI - Secretion of various endocrine substances by ACTH-secreting tumors--gastrin, melanotropin, norepinephrine, serotonin, parathormone, vasopressin, glucagon. PMID- 4296749 TI - Mixed differentiation of primary carcinoma of the urinary bladder. PMID- 4296751 TI - Clinical assessment of growth-rate in human tumours. PMID- 4296750 TI - Influence of pituitary, thyroid, and adrenal hormones on norepinephrine turnover and metabolism in the rat heart. PMID- 4296752 TI - Incidence of Clostridium perfringens in fish and fish products. PMID- 4296753 TI - Hemadsorption by herpes simplex-infected cell cultures. PMID- 4296754 TI - Electron paramagnetic resonance studies on melanins. I. The effect of pH on spectra at Q band. PMID- 4296755 TI - A hexacoordinated low-spin cobalt(II) complex. PMID- 4296756 TI - Transplantability of cycasin-induced tumors in rats, with emphasis on nephroblastomas. PMID- 4296757 TI - Long-term propagation of a murine erythroblastosis virus in vitro. PMID- 4296758 TI - Influence of host genotype on responses to four strains of avian leukosis virus. PMID- 4296759 TI - Secretion of cortisol, corticosterone and aldosterone in children with hypopituitarism. PMID- 4296760 TI - The ultrastructure of human mixed salivary tumors. PMID- 4296761 TI - Intermittent corticosteroid treatment of demyelinating diseases in childhood. PMID- 4296762 TI - Abortive transformation by polyoma virus. PMID- 4296763 TI - Blastomogenic effect of dimethylnitrosamine on pregnant rats and their offspring. PMID- 4296764 TI - [Effect of ultrasonic waves to the sensitivity of bacterial cells to polypeptide antibiotics (gramicidin S and polymyxin M)]. PMID- 4296765 TI - Tonic and phasic changes in threshold of arousal during desynchronized sleep. PMID- 4296766 TI - Cerebellar responses evoked by somatic afferent volleys during sleep and waking. PMID- 4296767 TI - Transmission of sensory information throug ascending spinal hindlimb pathways during sleep and wakefulness. PMID- 4296768 TI - [Heterogenet and properties of lactic dehydrogenase of the serum of the goose]. PMID- 4296769 TI - [Modifications of the metabolism of the phospholipids of E. coli consecutive to the action of colchicine K]. PMID- 4296770 TI - [Postpartum metabolic status in diabetis mellitus]. PMID- 4296771 TI - A superior thin-layer chromatographic procedure for the separation of aza arenes and its application to air pollution. PMID- 4296773 TI - The detection of diethylstilboestrol (DES) in urine by thin-layer chromatography. PMID- 4296772 TI - Phospholipids of human hair lipids. PMID- 4296774 TI - A common solvent impurity resembling a tocopherol. PMID- 4296775 TI - Thin-layer chromatographic separation and detection of methysergide and methergine. PMID- 4296776 TI - The identification of some amino acids in the presence of 50 percent glycerol, on silica gel thin layers. PMID- 4296777 TI - Determination of the degradation products of ethylenebis(dithiocarbamates) by thin-layer chromatography and some investigations of their decomposition in vitro. PMID- 4296778 TI - [Virus infections of the respiratory tract in childhood]. PMID- 4296779 TI - [Melanophore-stimulating activity of amino acids]. PMID- 4296780 TI - [Magnetic resonance in pharmacologic research]. PMID- 4296781 TI - The in vivo effect of ACTH on the activity in lipase in rat adrenal. PMID- 4296782 TI - [Neurotropic carcinogenic effect of phenyldimethyltriazene on rats]. PMID- 4296783 TI - [On the alkali-ion effect on partial reactions of ribosomal peptide synthesis]. PMID- 4296784 TI - [Toxicologic study and experimental antitumor activity of rubidomycin (13,057 R.P.)]. PMID- 4296785 TI - [Anticancer chemotherapy with rubidomycin (preliminary note on 14 cases]. PMID- 4296786 TI - Two pathways transmitting vestibulospinal influences from the lateral vestibular nucleus of Deiters to Extensor Fusimotor Neurones. PMID- 4296787 TI - [The glycerol-1-phosphate oxidase compensation phenomenon of Pette and Bucher in skeletal and heart muscle of different animal classes (rat and pigeon)]. PMID- 4296789 TI - A serologic survey for arbovirus antibodies in inhabitants of a southwest Taiwan village. PMID- 4296788 TI - [Study of B.S.P. metabolites and some histo-enzymologic modifications under the influence of aspartic acid]. PMID- 4296790 TI - [Radioisotope procedures, laterally divided kidney function tests and the angiotensin infusion test in patients with hypertension and renal artery stenosis]. PMID- 4296791 TI - [Value of cortisone in the management of virus encephalitis]. PMID- 4296792 TI - Control by factors in serum of multiplication of uninfected cells and cells infected and converted by avian sarcoma viruses. PMID- 4296794 TI - [Follow-up examinations in long-term ambulatory management of fast-type, absolute arrythmias with digitoxin]. PMID- 4296793 TI - A growth regulating factor in rat liver. PMID- 4296795 TI - [Polyetiology of a viral meningitis epidemic]. PMID- 4296796 TI - [On the problem of intravenous ACTH injection tolerance]. PMID- 4296797 TI - [On resorption and distribution of methyl-ethyl-succinimide (MES) in serum and cerebrospinal fluid in children]. PMID- 4296799 TI - Polyneuropathy in children. PMID- 4296798 TI - [Comparative studies of "bone age" and "tooth age" of children in families and in nurseries during the ages of 6 to 30 month]. PMID- 4296800 TI - Skeletal development as a measure of biological development. PMID- 4296801 TI - Skeletal age of children with congenital heart disease. PMID- 4296803 TI - [Enzyme histochemical studies on the effect of gonadotropins on the infantile rat ovary]. PMID- 4296802 TI - [Guinea pig diseases caused by Cl. perfringens type A]. PMID- 4296804 TI - [Estradiol and progesterone induced changes in experimental deciduoma of the rat]. PMID- 4296805 TI - [Therapy of hyperemesis using cortisone and ACTH]. PMID- 4296806 TI - The influence of embryonic tissue on growth of transplantable chrysoidin hepatoma. PMID- 4296807 TI - Studies on the adaptive properties of CoxsackieA4 viruses. PMID- 4296808 TI - Effect of long-term administration of ACTH and adrenocortical hormones on the course of hydrazide convulsions. PMID- 4296810 TI - [The effect of kinin hormones on urine dilution and urine concentration. 1. Studies on diuresis]. PMID- 4296809 TI - Influence of drugs, rate changes and temperature on myocardial stimulation by hypoxia. PMID- 4296811 TI - [Study of a case of amnesic encephalitis of herpetic origin]. PMID- 4296812 TI - [Comparative study of the pressor effect of beta-angiotensin II, of ethyladrianol and of mephentermine]. PMID- 4296813 TI - [On the clinical aspects and therapy of parotid gland tumors]. PMID- 4296814 TI - [Management of diabetic retinopathies using conjugated estrogens]. PMID- 4296815 TI - [The influence of aldosterone and aldosterone antagonists on the pressor effect of synthetic Angiotensin II in primary chronic adrenal cortex insufficiency (M. Addison)]. PMID- 4296817 TI - [Ribonuclease activity in the nervous system and its tumors]. PMID- 4296816 TI - [ACTH determination in the plasma from the cranial bulb of the jugular vein]. PMID- 4296818 TI - [Unusual surgical recanalization of the trachea in cylindroma]. PMID- 4296819 TI - [Experiences with discography of the cervical and lumbar spine]. PMID- 4296820 TI - [A biological assay for immune serums of swine infected with hoof and mouth disease (MKS)]. PMID- 4296821 TI - [On the resistance of shigellae to antibiotics in the course of acute dysentery in children]. PMID- 4296822 TI - [On the diagnosis of pertussis with the immunofluorescence method]. PMID- 4296823 TI - Infectious RNA derived from bovine virus diarrhoea virus. PMID- 4296824 TI - Behcet's syndrome with neurological manifestations in two sisters. PMID- 4296825 TI - Life threatening disease. An unusual case of severe burns, meningitis, obstructive hydrocephalus and neuroblastoma in a child under age two. PMID- 4296826 TI - Cystic disease of liver and kidney with portal hypertension. A cause of sudden unexpected hematemesis. PMID- 4296827 TI - Angiography in abdominal tumours in childhood with particular reference to neuroblastoma and Wilms' tumour. PMID- 4296828 TI - [Smallpox in Regensburg. A clinical and epidemiological analysis of 2 patients]. PMID- 4296829 TI - The mechanism of end product inhibition of serine biosynthesis. II. Optical studies of phosphoglycerate dehydrogenase. PMID- 4296830 TI - The mechanism of end product inhibition of serine biosynthesis. 3. Physical and chemical properties of phosphoglycerate dehydrogenase. PMID- 4296831 TI - Location of chromophoric residues in proteins by solvent perturbation. IV. Tyrosyl residues in ribonuclease. PMID- 4296832 TI - Activation of skeletal muscle phosphorylase kinase by adenosine triphosphate and adenosine 3',5'-monophosphate. PMID- 4296833 TI - Reversal of phosphorylase kinase activation. PMID- 4296834 TI - Studies on the phospholipid requirement of glucose 6-phosphatase. PMID- 4296835 TI - The anaerobic incorporation of 32P into adenosine triphosphate by Hymenolepis diminuta. PMID- 4296836 TI - The effect of cysteine on L-alpha-glycerophosphate and lactate dehydrogenase reactions. PMID- 4296837 TI - Kinetics and substrate binding of myosin adenosine triphosphatase. PMID- 4296838 TI - The biosynthesis of folic acid. 8. Purification and properties of the enzyme that catalyzes the production of formate from carbon atom 8 of guanosine triphosphate. PMID- 4296839 TI - Purification and properties of citraconase. PMID- 4296840 TI - A comparison of glycopeptides derived from soluble and insoluble collagens. PMID- 4296841 TI - An electron paramagnetic resonance study of the iron and copper complexes of transferrin. PMID- 4296842 TI - Kinetic studies on the mechanism of the malate dehydrogenase reaction. PMID- 4296843 TI - Reconstitution of the mitochondrial oxidation chain from individual components. PMID- 4296844 TI - Conditioned glycemic responses in the control of food intake. PMID- 4296846 TI - Granular cell myoblastoma: report of case. PMID- 4296845 TI - Oxidative phosphorylation in mitochondria of developing rat brain. PMID- 4296847 TI - Cardiovascular actions of guancydine in normotensive and hypertensive animals. PMID- 4296848 TI - Acute nephritis presenting with a normal urine. Report of a case. PMID- 4296849 TI - Linitis plastica associated with complete situs inversus. Report of a case. PMID- 4296850 TI - [Adrenal cortex hormone secretion disorders and their clinical aspects]. PMID- 4296851 TI - [Clinical aspects of catecholamine secretion disorders]. PMID- 4296852 TI - Ultracytochemical changes of the glucose-6-phosphatase (D-glucose-6-phosphate phosphohydrolase) activity in liver cells of the rat treated with phenobarbital. PMID- 4296853 TI - [On asymptomatic peripheral polyneuropathies]. PMID- 4296854 TI - Salvage of "sleeve-like" amputation of a digit. PMID- 4296855 TI - Hepatography with oily contrast medium injected via the portal vein system. PMID- 4296856 TI - [Pancreopathic hypoglycemia]. PMID- 4296857 TI - [Evolution of the interrenal organ in the female Gambusia sp. (Fish, Teleostei)]. PMID- 4296858 TI - [The plasma level of free corticosterone in birds after hypophysectomy or hypothalamo-hypophysis disconnection]. PMID- 4296859 TI - Demonstration of a viral protein intervening in the reproduction of avian smallpox virus. PMID- 4296860 TI - A change in growth potential of cells after conversion by Rous sarcoma virus. PMID- 4296861 TI - [Carotid gland tumor (paraganglioma, glomus tumor) of the neck]. PMID- 4296863 TI - [Differential compleion of mitosis in neuroectodermal and mesodermal tumors]. PMID- 4296862 TI - Nuclear RNA patterns in rat liver and hepatomas. PMID- 4296864 TI - [Neurogenous endothoracic tumors in infants and adults]. PMID- 4296865 TI - Carcinoid of the bronchus. PMID- 4296866 TI - Comparative chronic toxicity of three oral estrogens in rats. PMID- 4296867 TI - Evidence for the presence of 2-(o-cresyl)-4H-1:3:2-benzodioxaphosphoran-2-one in cat intestine following tri-o-cresyl phosphate administration. PMID- 4296869 TI - [Fibrosing angioma of the myocardium, at the same time, a contribution to the recognition of hamartomas and paraphrased myocardial lesions]. PMID- 4296868 TI - [Contribution to the arterial supply of subendocardial myofibrils in experimental myocardial infarct of the rat, using enzyme-histochemical examination methods]. PMID- 4296870 TI - [Studies on safety tests of inactivated poliomyelitis vaccines. IV. Comparative safety tests in rhesus monkeys and long-tailed monkeys (Cercopithecus aethiops)]. PMID- 4296871 TI - [Studies on safety tests of inactivated poliomyelitis vaccines. V. Pathomorphological changes in the CNS of rhesus monkeys (Macaca rhesus) and long tailed monkeys (Cercopithecus aethiops) following intracerebral and intralumbar inoculation with inactivated poliovirus types I, II, and 3]. PMID- 4296872 TI - [Comparative virological, fluorescence serological and cytological studies with a bovine para-influenza-3-virus]. PMID- 4296873 TI - Trophoblastic diseases in Taiwan. PMID- 4296874 TI - [The behavior of serum phosphatides under the influence of muscle relaxants]. PMID- 4296875 TI - Control of fatty acid synthesis in homogenate preparations of mouse hepatoma BW 7756. PMID- 4296876 TI - The oxidation of horseradish peroxidase by periodate. PMID- 4296877 TI - Glycogen synthesis and I to D conversion of glycogen synthetase in ascites hepatoma cells. PMID- 4296878 TI - The effect of catecholamines on the adenyl cyclase of frog and tadpole hemolysates. PMID- 4296879 TI - Comparative histochemical distribution of glycogen and alkaline phosphatases in the placenta. PMID- 4296881 TI - [Enzyme histochemistry of human brain tumors and their tissue culture. II. Oxydoreductases in ependymomas with quantitative findings]. PMID- 4296880 TI - [Cytochemical demonstration of cytochrome oxidase and peroxidases in fungi]. PMID- 4296882 TI - [Cytochemical localization and characterization of phosphate splitting enzymes in the sarcotubular system of cross striated muscles]. PMID- 4296883 TI - [Enzymatic reactions in tritium-water, IV. Apparent nullification of the stereospecificity of enzymatic tritium transfer by means of NAD]. PMID- 4296884 TI - [Isolation and purification of amyloid]. PMID- 4296885 TI - [Measurement of insulin activity in isolated fat cells]. PMID- 4296886 TI - [Studies on the biosynthesis of cyclitol, 18. On the mode of action of the enzyme from Candida utilis in converting D-glucose-6-phosphate to L-1-O-phospho-myo inositol]. PMID- 4296887 TI - Acute infectious bovine rhinotracheitis and salmonellosis in a dairy herd. PMID- 4296888 TI - Oxidative phosphorylation in Micrococcus denitrificans. 3. ATP-supported reduction of NAD+ by succinate. PMID- 4296889 TI - Lipids of Streptomyces sioyaensis. PMID- 4296890 TI - Development of hepatic lesions in calves fed with ragwort (Senecio jacobea). PMID- 4296891 TI - Agar gel diffusion studies of paravaccinia viruses. PMID- 4296892 TI - Isolation of parainfluenza virus from the lungs and nasal passages of sheep showing respiratory disease. PMID- 4296893 TI - Effects of hypophysectomy and several hormone replacement therapies upon patterns of nucleic acid and protein synthesis and enzyme levels in lactating rat mammary glands. PMID- 4296894 TI - Synthesis of the four pairs of side-chain epoxides epimeric at carbon 20 derived from 5-beta-pregnan-3-alpha-ol. PMID- 4296895 TI - The mode of development of Japanese encephalitis virus in the mosquito Culex tritaeniorhynchus summorosus as observed by the fluorescent antibody technique. PMID- 4296897 TI - Comparative studies on the breeding habits of a laboratory adapted variant and wild colonies of Culex tritaeniorhynchus summorosus, the principal vector of Japanese encephalitis. PMID- 4296896 TI - Hemagglutination inhibition antibody titers against Japanese encephalitis virus from human and pig sera of Amami-Oshima Island. PMID- 4296898 TI - [Adrenocorticotropic effects of beta 1-24 tetracosapeptide. (Study of excretion of 17-OHCS, of 17-KS and of pregnanetriol)]. PMID- 4296900 TI - Methylcholanthrene-induced sarcoma in singly fractured bone of mice. PMID- 4296899 TI - [Studies on mycobacteria for pyrophosphate uptake, pyrophosphatase activity and their influencing through ionizing radiation]. PMID- 4296901 TI - [Biological properties of virus strains, reproduced from infectious ribonucleic acid neurotropic foot-and-mouth disease virus mutants]. PMID- 4296902 TI - [Virological and serological studies of the internal eye in foot-and-mouth diseased cattle. I. Virus demonstration and tenacity test]. PMID- 4296903 TI - [Virological and serological studies of the internal eye in foot-and-mouth diseased cattle. II. Neutralization test and intraocular infection of guinea pigs]. PMID- 4296904 TI - Growth characteristics of Japanese encephalitis virus in chick embryo cells with special reference to the applicability of the culture to the production of inactivated vaccine. PMID- 4296905 TI - Murine cytomegalovirus: observations on growth in vitro, cytopathic effect, and inhibition with 5-Iododeoxyuridine. PMID- 4296907 TI - [Glucocorticoids and glucose metabolism. 2. Studies on the influence of metopirone on glucose tolerance with and without additional application of adrenocorticotropic hormone and prenisolone]. PMID- 4296908 TI - [The role of the pyramidal system in sensomotor integration]. PMID- 4296906 TI - [On histochemical enzyme demonstration in skin pathogenic fungi. II. Dermatophytes]. PMID- 4296909 TI - [Effect of hydrolytic enzymes on the so-called pseudo-end groups of DNA]. PMID- 4296910 TI - [Physiologic mechanisms of macrostructural changes in peripheral blood proteins under different functional states of the central nervous system]. PMID- 4296912 TI - [On the differential diagnosis of alveolar cell carcinoma (bronchial carcinoma or malignant pulmonary adenomatosis)]. PMID- 4296911 TI - [On the disturbance of the reflex and coordination activity of the spinal cord during intoxication with pyrophos]. PMID- 4296913 TI - [On clinical aspects of sudden unilateral isolated vestibular nerve disorders]. PMID- 4296914 TI - [The influence of angiotensin II on the tubular phosphate back resorption in humans. A contribution on the method of action of angiotensin]. PMID- 4296915 TI - [Differential diagnosis of primary amenorrhea]. PMID- 4296916 TI - [Management of postabortion anuria]. PMID- 4296917 TI - [Virus hepatitis and pregnancy. Frequency and reciprocal influence]. PMID- 4296918 TI - [Medicamentous therapy of rheumatic diseases in the spa?]. PMID- 4296919 TI - [Studies of phosphate therapy of urinary calculi]. PMID- 4296920 TI - [The biochemical basis of the biosynthesis of cholesterol and fatty acids]. PMID- 4296921 TI - [Biochemistry, pharmacology and clinical use of Angiotensin. I. Biochemistry]. PMID- 4296922 TI - [2 cases of a granular cell myoblastoma]. PMID- 4296923 TI - [On the assessment of the results of serological reactions. I. Individual titers]. PMID- 4296924 TI - [Metabolically conditioned forms of imbecility and their diagnosis. II. Galactosemia]. PMID- 4296925 TI - [Benign tumors of the larynx]. PMID- 4296926 TI - [The so-called myoblastic myoma and its malignant disease course]. PMID- 4296928 TI - [Susceptibility of baby mice to the virus of vesicular stomatitis in intracerebral and intraperitoneal infection]. PMID- 4296927 TI - Rabbits' corneal cells studied in tissue cultures. II. Enzyme reactions. PMID- 4296929 TI - [Oncolysis of malignant gliomas through apathogenic clostridia (strain "M 55")]. PMID- 4296930 TI - [Our experience with corticosteroid therapy in severe cerebral trauma]. PMID- 4296931 TI - [Simultaneous occurrence of basilar impression and brain tumor]. PMID- 4296932 TI - The roentgenographic findings in total lipodystrophy. PMID- 4296933 TI - Wilms' tumor. PMID- 4296934 TI - Toxoplasmosis complicating malignancy. Experience at the National Cancer Institute. PMID- 4296935 TI - Chemodectomas (nonchromaffin paragangliomas) of the head and neck. A clinicopathologic study. PMID- 4296936 TI - Inhibition of thymidylate kinase and DNA polymerase by the periodate oxidation product of beta-D-ribosyl-6-methylthiopurine. PMID- 4296937 TI - The utilization of trytophan and its metabolites for pyridine nucleotide synthesis in tumors and host liver. PMID- 4296938 TI - Sequential morphologic changes in aflatoxin B carcinogenesis in the rat. PMID- 4296939 TI - Immunosuppressive and antitumor activity of periodate oxidation product of beta-D ribosyl-6-methylthiopurine. PMID- 4296940 TI - Localization of "spontaneous" and Rous sarcoma virus-induced breakage in specific regions of the chromosomes of the Chinese hamster. PMID- 4296941 TI - Acceleration of leukemogenesis in AKR mice by grafts, cell suspensions, and cell free centrifugates of thymuses from preleukemic AKR donors. PMID- 4296942 TI - Murine sarcoma virus (Harvey): characteristics of focus formation in mouse embryo cell cultures, and virus production by hamster tumor cells. PMID- 4296943 TI - Studies on carcinogenesis by avian sarcoma viruses. 8. Glycolysis and cell multiplication. PMID- 4296944 TI - Report on the workship on virus induction by cell association. PMID- 4296945 TI - Birth order and desire for and participation in psychiatric posthospital services. PMID- 4296947 TI - Further properties of the balanced-detector electron spin resonance spectrometer. PMID- 4296948 TI - Practical methods of dating skeletal remains: a preliminary study. PMID- 4296946 TI - Complications of cardiac catheterization and angiography. Catheterization laboratory experience in a small hospital. PMID- 4296949 TI - Studies on the pancreatitis in a mouse hepatitis virus (MHV-3) infection. PMID- 4296950 TI - Influence of chronic exercise and electrical stress on hepatic glucose-6 phosphatase activity in rats. PMID- 4296951 TI - An uncommon indication for chlorpheniramine. PMID- 4296952 TI - Vascular responses in mesenteric arteries from genetic and renal hypertensive rats. PMID- 4296953 TI - Control of reduced diphosphopyridine nucleotide oscillations in beef heart extracts. I. Effects of modifiers of phosphofructokinase activity. PMID- 4296954 TI - Control of reduced diphosphopyridine nucleotide oscillations in beef heart extracts. II. Oscillations of glycolytic intermediates and adenine nucleotides. PMID- 4296955 TI - Control of reduced diphosphopyridine nucleotide oscillations in beef heart extracts. 3. Purification and kinetics of beef heart phosphofructokinase. PMID- 4296956 TI - Association of alpha-S-casein C in the alkaline pH range. PMID- 4296957 TI - Vitamin D3 induction of a calcium-binding protein in the uterus of the laying hen. PMID- 4296958 TI - Adenine nucleotide inhibition of pea malate dehydrogenase. PMID- 4296959 TI - Studies of the electron transport systems of heart muscle: biochemical and antigenic properties of a soluble DPNH dehydrogenase. PMID- 4296960 TI - Formation of delta-3-isopentenyl monophosphate and pyrophosphate in the latex of Hevea brasiliensis. PMID- 4296961 TI - Facial paralysis and otological symptoms due to secondary carcinoma. PMID- 4296962 TI - On metabolites of acetyldigoxin-beta in the heart muscle and blood of rats after oral administration of glycoside. PMID- 4296963 TI - The toxic proteins of cobra venom. PMID- 4296964 TI - The effects of neuromuscular blocking agents on mitochondria. IV. Effects of d tubocurarine, pyrrolizidine alkaloids and magnesium on oxidative phosphorylation. PMID- 4296965 TI - The metabolism of the octamethylene-1,8-dithiol moiety of bis(O acetylthiamine)octamethylene-18,-disulfide in rat and man. PMID- 4296967 TI - Corticotrophin in multiple sclerosis and retrobulbar neuritis. PMID- 4296966 TI - The intracellular distribution of mercury in rat liver after a single injection of mercuric chloride. PMID- 4296968 TI - Treatment for facial palsy. PMID- 4296970 TI - Heat and radiation resistance and activation of spores of Clostridium welchii. PMID- 4296969 TI - Studies on the pharmacology of alpha-methyl-3,4-dihydroxyphenylalanine (alpha methyl-dopa) and alpha-methyl-norepinephrine. I. PMID- 4296971 TI - Low temperature growth characteristics of clostridia. PMID- 4296972 TI - Magnetic resonance studies on irradiated crystals of chloroacetyl DL-alanine. PMID- 4296973 TI - Biological timing and the dento-facial complex. PMID- 4296974 TI - Kinins, beta-adrenergic receptors and functional vasodilatation in the submaxillary gland of the cat. AB - 1. The close arterial infusion of bradykinin into the submaxillary gland of the cat produced a pronounced hyperaemia that could be blocked by simultaneous perfusion of the gland with blood containing carboxypeptidase B. Carboxypeptidase B, however, failed to reduce the vasodilatation of chorda tympani nerve stimulation suggesting that the kinins are not involved in the regulation of submaxillary gland blood flow.2. Isoproterenol injections produced pronounced salivary gland vasodilatation. Beta-adrenergic blocking drugs reduced or abolished the hyperaemia of isoproterenol and reduced that of chorda tympani nerve stimulation. The combination of beta-blocking drugs and atropine could abolish or reduce further this nerve induced hyperaemia.3. The above results suggest that stimulation of cholinergic and beta-adrenergic receptors could account for the chorda tympani induced hyperaemia. Conclusive proof of this possibility remains to be determined. PMID- 4296975 TI - Pharmacology of pH effects on carotid body chemoreceptors in vitro. AB - 1. The carotid body and the carotid nerve were removed from anaesthetized cats and placed in a small Perspex channel through which Locke solution (at various pH values and usually equilibrated with 50% O(2) in N(2)) was allowed to flow. The glomus was immersed in the flowing solution while the nerve was lifted into oil covering the saline. Sensory discharges were recorded from the nerve and their frequency was used as an index of receptor activity. At times, a small segment of carotid artery, containing pressoreceptor endings, was removed together with the glomus. In this case, pressoreceptor discharges were recorded from the nerve.2. The amplitude of either chemo- or pressoreceptor discharges was not changed by strong acid solutions. Acid decreased the frequency of the baroreceptor discharges only when pH fell to less than 4.0. Solutions at low pH increased the chemosensory discharge, but acid depressed the increased chemoreceptor discharge elicited by KCl. These experiments indicated that H(+) ions probably acted as membrane ;stabilizers' without depolarizing either the nerve fibres or endings.3. Acid solutions increased the action of acetylcholine chloride (AChCl) (100-200 mug) on chemoreceptors. This effect probably was due either to inactivation of tissue cholinesterase or to enhanced sensitivity of the sensory endings to ACh.4. Choline chloride (10(-3)M), which favours ACh synthesis, protected the preparation against decay during prolonged experimentation. Hemicholinium-3 (HC 3), which blocks ACh synthesis in low concentrations (10(-5)M), depressed the chemosensory response to acid and to hypoxia when such stimuli were applied repeatedly. This concentration of HC-3 did not change effects of applied ACh.5. Substances which affect ACh release markedly changed the chemoreceptor discharge increase induced by acidity and other forms of stimulation. In the absence of Ca(2+), acid, anoxia, and interruption of flow provoked receptor depression while receptor excitation induced by ACh and KCl persisted. All stimuli excited and showed increased effectiveness as the Ca(2+) concentration was raised, but their effects declined as Ca(2+) was increased above normal values. Mg(2+) ions depressed the chemoreceptor effects induced by all these stimuli. The action of Mg(2+) was not due entirely to nerve ending block. Morphine sulphate (which decreases ACh release in other structures) also depressed the receptor response to acid and flow interruption.6. Cholinergic blocking agents such as mecamylamine, hexamethonium, atropine, dihydro-beta-erithroidine (DHE), HC-3 (10( 4)M), choline and acetylcholine (in combination with choline) depressed the effects of acid and ACh on the chemoreceptors. The effect induced by interruption of flow was depressed only by mecamylamine and DHE.7. Agents which affect the fate of released ACh, such as acetylcholinesterase and eserine salicylate, did not affect clearly the response of chemoreceptors to acid.8. The results suggest that acid stimulates chemoreceptor fibres through an indirect mechanism, viz. through increased release and/or decreased destruction of a presynaptic transmitter from the glomus cell. This transmitter is probably ACh (see following paper, Eyzaguirre & Zapata, 1968). PMID- 4296977 TI - Acetylcholine stimulation of the phosphodiesteratic cleavage of guinea pig brain phosphoinositides. PMID- 4296978 TI - Castor bean FDPase from endosperm tissue: properties and partial purification. PMID- 4296976 TI - The release of acetylcholine from carotid body tissues. Further study on the effects of acetylcholine and cholinergic blocking agents on the chemosensory discharge. AB - 1. Both carotid bodies were removed from cats and placed in a small Perspex channel through which Locke solution was allowed to flow under a layer of paraffin oil. Stimulation of the upstream (;donor') organ elicited an increased sensory discharge in the downstream (;detector') preparation (Loewi effect).2. This effect was enhanced by eserine, depressed by hexamethonium and blocked by either mecamylamine or acetylcholinesterase. The Loewi effect did not disappear when chronically denervated (4 days) ;donor' carotid bodies were stimulated.3. These experiments led to the conclusion that ACh is released by the carotid body tissues (probably from the glomus cells) during stimulation and that this substance is responsible for the initiation of the chemosensory discharges.4. In single preparations the chemosensory endings proved to be very sensitive to ACh especially in the presence of eserine which, in all probability, inactivated the tissue cholinesterase. Curarizing agents such as mecamylamine, hexamethonium, (+) tubocurarine and atropine blocked the response of the sensory endings to applied ACh in what appeared to be ;surmountable' antagonism. PMID- 4296979 TI - The effect of growth on the levels of acylphosphatase and some glycolytic enzymes in rat muscle. PMID- 4296980 TI - Treatment of diseases of the ovaries affecting growth and development. PMID- 4296981 TI - Curare and acetylcholine receptor substance. PMID- 4296982 TI - In vitro regulation of the lipolysis of adipose tissue. PMID- 4296983 TI - Effect of bromide ions on junctional transmission. PMID- 4296984 TI - Single strand scissions of DNA caused by a carcinogen, 4-hydroxylaminoquinoline 1 oxide. PMID- 4296985 TI - Mechanically induced free radicals in bone. PMID- 4296986 TI - Validity of a method measuring transmitter release from the central nervous system. PMID- 4296987 TI - Electron spin resonance of ferromagnetic particles in airborne dust. PMID- 4296988 TI - Vascular reactivity in human hypertension. PMID- 4296989 TI - Vascular reactivity in experimental hypertension. PMID- 4296990 TI - The morphological basis for the sympathetic control of blood vessels. PMID- 4296991 TI - The low energy portion of the electron spectrum established within and emitted from irradiated conducting materials. PMID- 4296992 TI - Malignant tumours of the genito-urinary tract in childhood. PMID- 4296993 TI - Complications in the management of surgical disease of the major salivary glands. PMID- 4296994 TI - Mediastinal cysts and tumors. An analysis of 96 cases. PMID- 4296996 TI - Use of isoxsuprine in uterosalpingography and uterotubal insufflation. PMID- 4296995 TI - [Clinical aspects of parainfluenzal infection in adults]. PMID- 4296997 TI - A method for radiologic detection of fetal maturity. PMID- 4296998 TI - The presence of a vasoconstrictive substance in toxemia. PMID- 4296999 TI - Prolonged remission of diarrhea due to nonbeta islet cell tumor of the pancreas by radiotherapy. PMID- 4297000 TI - Duration of prophylactic effect of statolon against mengovirus in mice. AB - Intraperitoneal injection of statolon into mice is known to exert a protective effect against a subsequent infection with a variety of viruses owing to stimulation of production of interferon. To study the duration of such protection, groups of mice were treated with 350 mug of statolon at 69, 55, 41, 27, 13, 6, or 1 day prior to a challenge with mengovirus. Other groups were treated with 760 mug at 1 to 6 days before challenge. Ten days after inoculation with the virus, LD(50) determinations were made for each group. Mice which received statolon 1 to 5 days before infection were significantly more resistant to the virus than nontreated controls; no protection could be demonstrated in the other groups. PMID- 4297002 TI - [Possibilities of homotransplantation depending on tissue metabolism]. PMID- 4297001 TI - Use of phenolphthale in diphosphate agar with polymyxin as a selective medium for the isolation and enumeration of coagulase-positive staphylococci from foods. PMID- 4297003 TI - Reaction of the carcinogen 4-hydroxyaminoquinoline 1-oxide with sulfhydryl groups of proteins. PMID- 4297005 TI - Inhibition of hexobarbital metabolism by diethylnitrosamine. PMID- 4297004 TI - Plasma "angiotensinase" activity as a determinant of angiotensin pressor action and tachyphylaxis in the rat. PMID- 4297006 TI - Effects of acetone on responses of a number of tissues to biogenic amines. PMID- 4297007 TI - Studies of phosphorus metabolism by isolated nuclei. X. Nucleolar nucleosidediphosphatase activity. PMID- 4297008 TI - Methylation of RNA by mouse organs and tumors: ionic stimulation in vitro. PMID- 4297009 TI - RNA-DNA hybrids formed by ribosomal RNA from a rat hepatoma. PMID- 4297010 TI - Studies on messenger RNA from peanut plants: in vitro polyribosome formation and protein synthesis. PMID- 4297011 TI - The number of superhelical turns in mitochondrial DNA. PMID- 4297012 TI - Viral diseases of laboratory animals. PMID- 4297013 TI - [On prevention and treatment of sympathetic disease]. PMID- 4297014 TI - A new method for the microdetermination of free and total nonprotein-bound tryptophan in plasma. PMID- 4297015 TI - Gluconeogenesis in mouse kidney cortex. II. Glucose production and enzyme activities in newborn and early postnatal animals. PMID- 4297017 TI - Angiotensin infusion: a clinical evaluation as a screening test for renovascular hypertension. PMID- 4297018 TI - Effects of the potent nephrotogenic aminonucleoside of puromycin on phospholipid metabolism in rat kidney cortex subcellular fractions. PMID- 4297019 TI - Utilization of energy sources for potassium accumulation in EDTA-treated cells of Escherichia coli. PMID- 4297020 TI - Rabbit ileal loop response to strains of Clostridium perfringens. AB - The ligated loop of the rabbit intestine was investigated as a possible experimental model for the study of Clostridium perfringens food poisoning. The method of preparation of the challenge inoculum was important in determining whether a given strain would provoke a response. When cultures were grown for 4 hr at 37 C in Skim Milk (Difco), 14 of 29 type A strains isolated from food poisoning outbreaks consistently produced exudation of fluid and consequent dilation of the ileal segments. In contrast, 15 of the 18 strains derived from other sources failed to elicit a response. By use of different inoculum preparations, nearly all strains could be made to give at least an occasional positive loop reaction. Diarrhea was not obtained in rabbits by intraluminal injection into the normal ileum or by per os administration of the cultures. Lecithinase, purified and in concentrated culture supernatant fractions, failed to produce a response in the isolated ileal loops. PMID- 4297022 TI - Nature of unsaponifiable lipids of a Mycoplasma strain grown with isopentenyl pyrophosphate as a substitute for sterol. AB - Mycoplasma sp., strain J, which is unable to convert mevalonic acid to isopentenyl pyrophosphate (IPP) will grow with IPP as a substitute for sterol. (14)C-labeled IPP is incorporated into its unsaponifiable lipid. This unsaponifiable lipid was separated into three (14)C-labeled fractions, all of which possess spectral and chromatographic characteristics of polyterpenes. PMID- 4297021 TI - Isoleucine and valine metabolism of Escherichia coli. XV. Biochemical properties of mutants resistant to thiaisoleucine. AB - Thiaisoleucine-resistant mutants of Escherichia coli strain K-12 which exhibited reduced isoleucyl soluble ribonucleic acid synthetase activity were isolated. Resistance was apparently achieved by the selection of a synthetase with a 10 fold decrease in apparent affinity for thiaisoleucine. This mutation also resulted in a 2.5-fold decrease in apparent affinity for the natural substrate, l isoleucine, and less activity than found in wild type. The mutants grew more slowly than wild type and were derepressed for three of the five enzymes in the pathways to isoleucine and valine. PMID- 4297023 TI - Reduced nicotinamide adenine dinucleotide oxidation by Thiobacillus neapolitanus and Thiobacillus strain C. PMID- 4297024 TI - Insulinoma. PMID- 4297025 TI - Hyperinsulinism: a report of 12 cases at the University of Iowa Hospitals. PMID- 4297026 TI - Some biological characters of cell lines derived from normal rabbit kidney. PMID- 4297027 TI - Bronchiolar damage and emphysema: a study in rats. PMID- 4297028 TI - Effects of manganese on the response of aortic strips to angiotensin and norepinephrine contractions. PMID- 4297029 TI - The absence of sympathetic role in anti-ChE-induced changes in cholinergic transmission. PMID- 4297030 TI - Selective labeling of histamine in rat gastric mucosa: application to measurement of turnover rate. PMID- 4297031 TI - Free-radical intermediates in the reaction of the hydroxyl radical with amino acids. PMID- 4297032 TI - [Study by electron paramagnetic resonance and spectrophotometry of absorption of the primary processes in photochemistry of frozen aqueous solutions at 77 degree K of aromatic amino acids and polypeptides]. PMID- 4297033 TI - Studies on the correlation between the clinical course of mammary carcinoma and the mode of neoplastic infiltration. PMID- 4297034 TI - Clinical evaluation of damage to the superior cluneal nerves. PMID- 4297035 TI - Group psychotherapy in the sixties. PMID- 4297036 TI - Biosynthesis of phosphatides of N-ethyl analogs of choline in vivo and in vitro. PMID- 4297037 TI - Free radicals in human skin before and after exposure to light. PMID- 4297038 TI - Photoenhancement of the electron spin resonance signal from melanins. PMID- 4297039 TI - Studies on adrenal cortical cytochrome P-450. I. Effects of substrates and electron donors on its catalytic, spectral, and electron paramagnetic resonance properties. PMID- 4297040 TI - Organic structural specificity and sites of coenzyme Q in succinoxidase and DPNH oxidase systems. PMID- 4297041 TI - Mechanism of oxidation and phosphorylation of naphthoquinol diphosphates. PMID- 4297042 TI - [On the histochemical properties and origin of lipofuscin in certain pathological conditions of the liver]. PMID- 4297043 TI - [Histophysiology and histopathology of nonspecific phosphatases of the liver and kidney]. PMID- 4297044 TI - The lipid composition of Mycoplasma laidlawii strain B. AB - 1. Total lipid was extracted from Mycoplasma laidlawii strain B with chloroform methanol mixtures and fractionated into neutral lipid, glycolipid and phospholipid components by chromatography on silicic acid. 2. Saponification of the glycolipid fraction, which represented nearly half of the total lipid, yielded two glycosides for which the structures O-alpha-d-glucopyranosyl-(1-->1) d-glycerol and O-alpha-d-glucopyranosyl-(1-->2)-O-alpha-d-glucopyranosyl-(1-->1) d-glycerol were established. 3. The ratio of monoglucosyl diglyceride to diglucosyl diglyceride increased with the age of the culture, though the total glycolipid concentration remained virtually constant. The glycolipid concentration was unaffected by the addition of cholesterol to the culture medium. 4. The phospholipid fraction consisted of two components, phosphatidylglucose and phosphatidylglycerol. Organisms harvested at acidic pH also contained O-amino acyl esters of phosphatidylglycerol. No lipids containing inositol could be detected. PMID- 4297045 TI - The action of digitonin on rat liver mitochondria. Phospholipid content. AB - 1. The amount and types of phospholipid and the fatty acid composition of the various phospholipids were examined in intact rat liver mitochondria, in mitochondria devoid of their outer membrane (preparation A) and in very small pieces derived from the disruption of the inner-membrane complexes (preparation B). The latter two preparations were obtained by digitonin treatment and carry out oxidative phosphorylation. 2. The ratio mug.atoms of phospholipid P/mg. of protein was 0.163 for intact mitochondria, decreased to 0.118 on removal of the outer membrane and increased markedly to 0.292 on disruption of the inner membrane complex. 3. Examination of the various types of phospholipid present showed that the molar proportions cardiolipin:phosphatidylcholine:phosphatidylethanolamine were approx. 1:6:6 for intact mitochondria and 1:3:3 for preparations A and B. 4. There was a correlation between the recovery of cardiolipin and adenosine triphosphatase activity in the conversion of intact mitochondria into preparations A and B. 5. The fatty acid contents of the various types of phospholipid purified by thin layer chromatography were identical in all three preparations. Our results show a considerably higher content of arachidonic acid and lower content of oleic acid for phosphatidylcholine, phosphatidylethanolamine and phosphatidylinositol than have previously been reported for mitochondrial phospholipids. PMID- 4297046 TI - Fractionation of native and denatured transforming deoxyribonucleic acid from Bacillus subtilis. AB - 1. Native DNA from Bacillus subtilis was fractionated by stepwise elution from methylated albumin, the transforming activity being confined to two out of four fractions. Partial separation of DNA active in transformation for the arginine marker from that showing activity for the histidine and tryptophan markers was achieved. 2. Partial denaturation of DNA at 90 degrees and 93.5 degrees resulted in the preferential destruction of transforming activity for the histidine and tryptophan markers. 3. Denaturation of DNA at 100 degrees followed by chromatography on methylated albumin yielded five fractions, two of which exhibited residual activity. Redenaturation at 100 degrees resulted in the interconversion of four out of the five fractions. Redenaturation of fractions labelled with (15)N and (2)H suggested the presence of a specific component that did not readily take part in the interconversions. PMID- 4297047 TI - A study of the heterogeneous 37S ribonucleic acid induced by foot-and-mouth disease virus. AB - 1. The 37s RNA induced in baby-hamster kidney cells by infection with foot-and mouth-disease virus was examined on sucrose gradients and by filtration through Sepharose 4B. 2. The RNA sedimented faster (37s) and as a broader band than the 35s RNA from purified virus. 3. Treatment with deoxyribonuclease, Pronase or amylase did not alter the sedimentation profile of the 37s RNA. 4. Treatment of individual fractions of the RNA with phenol, dimethyl sulphoxide or methylCellosolve did not decrease the sedimentation rate of the faster sedimenting molecules. 5. Sedimentation in sucrose gradients of different ionic strengths or containing EDTA had no effect on the heterogeneous nature of the profile. 6. On filtration through Sepharose 4B columns, the 37s virus-induced RNA was eluted before viral RNA. 7. Only 20% of the rapidly sedimenting RNA was incorporated into complete virus particles. PMID- 4297048 TI - Studies in phytosterol biosynthesis. Mechanism of biosynthesis of cycloartenol. AB - 1. The mechanism of cycloartenol biosynthesis in leaves of Solanum tuberosum was investigated with the use of [2-(14)C,(4R)-4-(3)H(1)]mevalonic acid. 2. The (3)H/(14)C atomic ratio in cycloartenol was 6:6, the same as that in squalene; this eliminates lanosterol as a possible biosynthetic precursor of cycloartenol, and indicates that a hydrogen migration from C-9 to C-8 occurs. 3. Chemical isomerization of the cycloartenol to lanosterol ((3)H/(14)C ratio 5:6) and parkeol ((3)H/(14)C ratio 6:6) confirms the hydrogen migration from C-9 to C-8. 4. Possible mechanisms for the biosynthesis of cycloartenol and parkeol are discussed. 5. The (3)H/(14)C ratio for 24-methylenecycloartanol was 6:6, demonstrating that the hydrogen atom at C-24 is retained during alkylation of the cycloartenol side chain. PMID- 4297049 TI - Binding of phosphate ligands to ribonuclease A. PMID- 4297050 TI - Fructose diphosphatase from rabbit liver. IX. Isolation and kinetic properties of the enzyme-substrate complex. PMID- 4297051 TI - Ionic properties of acidic lipids. Phosphatidylinositol. PMID- 4297052 TI - The sterols of Ochromonas danica and Ochromonas malhamensis. PMID- 4297053 TI - Studies on the biosynthesis of the erythromycins. 3. Isolation and structure of 5 deoxy-5-oxoerythronolide B, a shunt metabolite of erythromycin biosynthesis. PMID- 4297054 TI - Transfer ribonucleic acids from Escherichia coli treated with 5-fluorouracil. PMID- 4297055 TI - Preparation of a mannopentaose, mannohexaose, and mannoheptaose from Saccharomyces cerevisiae mannan. PMID- 4297056 TI - Effects on mammalian adipose tissue of fragments of bovine insulin and of certain synthetic peptides. PMID- 4297057 TI - Studies on structures of polar dyes derived from the liver proteins of rats fed N methyl-4-aminoazobenzene. II. Identity of synthetic 3-(homocystein-S-yl)-N-methyl 4-aminoazobenzene with the major polar dye P2b. PMID- 4297058 TI - Studies on plasma membranes. V. On the lipid dependence of some phosphohydrolases of isolated rat-liver plasma membranes. PMID- 4297059 TI - Studies on plasma membranes. VI. Differences in the effect of temperature on the ATPase and (Na+-K+)-ATPase activities of plasma membranes isolated from rat liver and hepatoma. PMID- 4297061 TI - The lipid composition of rat-liver plasma membranes. PMID- 4297060 TI - Studies on plasma membranes. VII. A leucyl-beta-naphthylamidase-containing repeating unit on the surface of isolated liver and hepatoma plasma membranes. PMID- 4297062 TI - Comparative X-ray diffraction and electron microscope studies of isolated mitochondrial membranes. PMID- 4297063 TI - On coupling factors of oxidative phosphorylation. PMID- 4297064 TI - Cleavage of phycocyanobilin from C-phycocyanin. PMID- 4297065 TI - Electron spin resonance of non-haem iron in xanthine oxidase. PMID- 4297066 TI - Pituitary peptides. Naturally occurring analogues of porcine corticotropin. PMID- 4297067 TI - [Formation of complexes between p-benzosemiquinone and imidazole and its derivatives]. PMID- 4297068 TI - Electron spin resonance of four human hemoglobins. PMID- 4297069 TI - Fructose I,6-diphosphatase of mouse Ehrlich ascites tumor and its comparison with the enzymes of liver and skeletal muscle of the mouse. PMID- 4297070 TI - Extracellular collagenase produced by Streptomyces madurae. PMID- 4297071 TI - The intracellular localization of exonuclear and endonuclear "phosphodiesterase" activity by histochemical methods. PMID- 4297073 TI - Kinetic studies on DNA polymerase. PMID- 4297072 TI - Characterization and measurement of delta-aminolaevulinate synthetase in bone marrow cell mitochondria. PMID- 4297074 TI - [Detection of a specific viral antigen in the cells of Wistar rats infected with chicken erythroblastosis virus]. PMID- 4297075 TI - [A comparative study of some enzymes of transplantable human leukemia cells with acquired in vitro resistance to viruses]. PMID- 4297076 TI - [Halogenation of ribonucleic acids. VI. Influence of bromination on the transforming activity of Haemophilus influenzae DNA]. PMID- 4297077 TI - [Chromosomal evolution of a clone of human cells transformed by Rous sarcoma virus]. PMID- 4297078 TI - The glycolytic pathway in adult liver fluke, Fasciola hepatica. PMID- 4297079 TI - Histochemical detection of several enzymes in Cryptomphallus and Blaptica and its relation to neuromuscular transmission. PMID- 4297080 TI - Studies of the metabolism of Echinococcus granulosus. X. The mechanism of production of volatile fatty acids. PMID- 4297081 TI - Depletion of ascorbic acid from the adrenal of the intact embryo of Gallus domesticus by adrenocorticotrophic hormone or histamine. PMID- 4297082 TI - Studies of metabolism in embryonic development. II. Biosynthesis of lipids in embryonated trout ova. PMID- 4297083 TI - [On the treatment of epithelial neoplasms of the salivary glands]. PMID- 4297084 TI - Participation of potassium chloroplatinate in peroxidase-catalyzed oxidations by the extract of Japanese radish root. PMID- 4297085 TI - Alpha-glucan-phosphorylase in the striated muscle of the developing embryo of Gallus domesticus. PMID- 4297086 TI - [Phosphatases in rheumatic diseases]. PMID- 4297087 TI - Investigation of polymyxin E derivatives by thin-layer chromatography. PMID- 4297088 TI - Quantitative thin-layer chromatography of benzyloxycarbonyl dipeptide phenylhydrazides. PMID- 4297089 TI - An improved method for the separation and removal of organochlorine insecticides from thin-layer plates. PMID- 4297090 TI - The effects of a microlayer of silica on the retention of mandibular complete dentures. PMID- 4297091 TI - Resistance to alveolar monocytes to rabbitpox virus following intratracheal injection of parainfluenza-3 virus. PMID- 4297092 TI - Comparison of endotoxin blockade by estrogenic substances and hydrocortisone. PMID- 4297093 TI - The macrophage in allograft immunity. I. Effects of silica as a specific macrophage toxin. PMID- 4297094 TI - Activation of lateral geniculate neurons by electrical stimulation of superior colliculus in cats. PMID- 4297095 TI - The histogenesis of experimental viral mouse leukaemia. PMID- 4297096 TI - Mesothelioma of spermatic cord. PMID- 4297097 TI - Granular-cell schwannoma (myoblastoma). PMID- 4297098 TI - Biochemistry and physiology of taurine and taurine derivatives. PMID- 4297099 TI - [Pneumopathies caused by nitrous vapors. Apropos of a recently observed case]. PMID- 4297100 TI - [Association of an idiopathic hemochromatosis, a dyslipemia, and a dilation of the mesenteric lymphatic network]. PMID- 4297101 TI - [The neuro-psychic complications of chronic alcoholism]. PMID- 4297102 TI - [Non-myelomatous IgG and IgA paraproteinemias]. PMID- 4297103 TI - [Certainly malignant erythremias and minimal erythroleukemias (apropos of 11 cases)]. PMID- 4297104 TI - [Megakaryocytic hyperplasia and qualitative abnormalities of the megakaryocyte platelet series associated with acute myeloblastic leukemia]. PMID- 4297105 TI - [A case of anuria from osmotic nephropathy after perfusions of low molecular weight dextran]. PMID- 4297106 TI - [Neuro-psycho-social considerations apropos of a case of intersexuality]. PMID- 4297107 TI - [Peculiarities of small cell bronchial carcinoma]. PMID- 4297108 TI - [Reflections on the diagnosis of stomach cancer at onset]. PMID- 4297109 TI - [Absence of metabolic repercussions after widespread and prolonged cutaneous application of a corticoid ointment in young children]. PMID- 4297110 TI - [Thyroid osteosis]. PMID- 4297111 TI - [Meningeal listeriosis in a cirrhotic]. PMID- 4297112 TI - [Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses]. PMID- 4297113 TI - [Accelerometric and EMG study of abnormal movements and pathologic reflexes]. PMID- 4297114 TI - [2 cases of hemangiosarcoma of the liver. (Nosologic discussion)]. PMID- 4297115 TI - [Lymphoid hepatosplenomegaly]. PMID- 4297116 TI - [Is there a medical treatment for coxarthrosis?]. PMID- 4297117 TI - [Metoclopramide and hyperemesis gravidarum: a comparative evaluation in four cases]. PMID- 4297118 TI - [Treatment of hypercalcemia with phosphates]. PMID- 4297119 TI - A method for quantitative elution of microgram quantities of steroids from silica gel layers. PMID- 4297121 TI - Antigenic relationships among frog viruses demonstrated by the plaque reduction and neutralization kinetics tests. PMID- 4297120 TI - Further studies on the incorporation of cell DNA into polyoma-related particles. PMID- 4297122 TI - Group-specific viral antigens in the milk and tissues of mice naturally infected with mammary tumor virus or Gross leukemia virus. PMID- 4297123 TI - Further studies on RSV production form transformed cells. PMID- 4297124 TI - The inhibition of rabies virus by arabinosyl cytosine. Studies on the mechanism and specificity of action. PMID- 4297125 TI - The self-assembly of spherical viruses with mixed coat proteins. PMID- 4297126 TI - Relation between the adsorption to cells and antigenic properties in poliovirus particles. PMID- 4297127 TI - [Change in serological type of the causative agent of pertussis]. PMID- 4297128 TI - [Soluble complement-fixing antigen of phase I Bordetella pertussis]. PMID- 4297129 TI - [Characteristics of a soluble antigen of Haemophilus pertussis obtained by sucrose extraction]. PMID- 4297130 TI - Renal arterial hypertension. PMID- 4297131 TI - Estrogen effect on spontaneous atherosclerosis. Experimental studies in white carneau pigeon. PMID- 4297132 TI - Mono- and dimethyl phosphatidates from different subtypes of choline and ethanolamine glycerophosphatides. PMID- 4297133 TI - Drug reactions. I. A protein contaminant causing penicillin hypersensitivity. PMID- 4297134 TI - Dose-response relationship in angiotensin bioassay. PMID- 4297135 TI - [On the effect of heparin and corticoid therapy on the number of circulating eosinophils]. PMID- 4297136 TI - DNA and RNA content at successive postmitotic intervals in chick embryo fibroblasts infected with Rous sarcoma virus. PMID- 4297137 TI - [On the problem of food poisoning caused by Cl. perfringens of type A]. PMID- 4297138 TI - [Domestic animals as carriers of enteroviruses in man]. PMID- 4297139 TI - [Laboratory diagnosis of food poisoning caused by Cl. perfringens]. PMID- 4297140 TI - [On a new method for the determination of diamine oxidase activity]. PMID- 4297142 TI - [Linkage of heptose units in the core polysaccharide of lipopolysaccharides from R-mutants of Salmonella minnesota]. PMID- 4297141 TI - [Properties of a soluble inorganic pyrophosphatase from rat liver cell nuclei]. PMID- 4297143 TI - The basic proteins of cobra venom. I. Isolation and characterization of cobramines A and B. PMID- 4297144 TI - Bidimensional thin-layer chromatography of carbohydrates on silica gel impregnated with boric acid. PMID- 4297145 TI - Quantitative thin-layer chromatography of neutral lipids using semi-specific colorimetric and titrimetric techniques. PMID- 4297146 TI - Systematic identification of psychotropic drugs by thin layer chromatography. II. PMID- 4297147 TI - Renin and erythropoietin in normotensive and in hypertensive patients. PMID- 4297148 TI - Systemic corticosteroids in dermatology. PMID- 4297149 TI - Cancer of the urogenital tract: Wilms' tumor and neuroblastoma. Wilms' tumor. PMID- 4297151 TI - Radiation therapy in Wilms' tumor. PMID- 4297150 TI - The place of surgery in Wilms' tumors. PMID- 4297152 TI - Wilms' tumor. Comment. The prevention of metastases. PMID- 4297153 TI - [Case of spontaneous hypoglycemia]. PMID- 4297154 TI - Changes in structural, physiological and pharmacological properties of insect excitatory nerve-muscle synapses after nerve section. PMID- 4297155 TI - External chemical messengers. V. More functions of the pineal gland. PMID- 4297156 TI - Hypo-hyperparathyroidism. PMID- 4297157 TI - The effect of corticotrophin on hypothalmic-pituitary-adrenal function of children. PMID- 4297158 TI - Viral and cellular growth and sequential increase of protein and DNA during fowlpox infection in vivo (32700). PMID- 4297159 TI - Viomycin. Further degradative studies. PMID- 4297160 TI - Studies on DNA from low-density particles of SV40. I. Heterogeneous defective virions produced by successive undiluted passages. PMID- 4297161 TI - Studies on DNA from low-density particles of SV40. II. Noninfectious virions associated with a large-plaque variant. PMID- 4297162 TI - Electron microscopic study of cell fusion by HVJ virions. PMID- 4297164 TI - Controlled double infection with unrelated animal viruses. PMID- 4297163 TI - Role of hydrogen and disulfide bonds in polyoma capsid structure. PMID- 4297165 TI - The sedimentation profiles of cytoplasmic polyribosomes in mammalian cells productively and abortively infected with herpes simplex virus. PMID- 4297167 TI - Metabolic effects of hormones and drugs which may be mediated by the adenyl cyclos--cyclic 3-5 AMP system. PMID- 4297168 TI - [Detection of complement fixing antibodies against respiratory syncytial virus in groups of the population of the Federal Territory of Amapa, Brazil]. PMID- 4297170 TI - [Examination of foot-and-mouth disease virus strains with regard to their suitability for modified virus vaccine preparation]. PMID- 4297169 TI - Pituitary adenoma. Preoperative symptomatology in a series of 260 patients. PMID- 4297171 TI - [Immunochemical properties of preparations of bacteriophage 2C DNA]. PMID- 4297172 TI - [On the treatment of chronic surgical infections]. PMID- 4297173 TI - [Clinical studies on ACTH in the blood. I. Blood ACTH levels in normal subjects and in various endocrine diseases; effect of various steroids]. PMID- 4297174 TI - [Loss of transmission and ultrastructural change in the rat sympathetic ganglion placed in different incubation conditions]. PMID- 4297175 TI - [Biochemical basis for activity differences between sorbitol and fructose]. PMID- 4297176 TI - [On the mechanism of action of inducer substances. I. Fractionation of calf thymus chromatin and characterization of a specific DNA-protein complex]. PMID- 4297177 TI - [Synthesis of a new peptide substrate for collagenase according to the Merrifield method]. PMID- 4297178 TI - [Studies on the biosynthesis of cyclic compounds. XIX. On a D-glucose-6-phosphate to L-1-O-phospho-myo-inositol conversion enzyme from higher plants]. PMID- 4297179 TI - Electron paramagnetic resonance of beef-heart ferricytochrome c. PMID- 4297180 TI - Quantitative analysis on thin layer chromatograms: a theory for light absorption methods with an experimental verification. PMID- 4297182 TI - A rapid micro-method for the separation, identification and estimation of the purine bases: caffeine, theobromine and theophylline. PMID- 4297181 TI - Chromatographic studies on Canada balsam and some resin acids. PMID- 4297183 TI - Chromatographic investigation of fatty alcohols. PMID- 4297184 TI - Thin-layer chromatography of substituted glycosides. PMID- 4297185 TI - Thin-layer partition chromatography for urinary metabolites of cortisol. PMID- 4297186 TI - Identification of some naturally occurring alkyl-substituted phenols in cashew nut shell liquid by chromatographic techniques. PMID- 4297187 TI - Studies in prebiotic synthesis. II. Synthesis of purine precursors and amino acids from aqueous hydrogen cyanide. PMID- 4297188 TI - [Cushing's syndrome caused by a non-endocrine pulmonary tumor]. PMID- 4297189 TI - [Studies on the antigenic structure of anatoxins of Clostridium perfringens, Cl. oedematiens, Cl. septicum and Cl. tetani by determining their fixation properties]. PMID- 4297190 TI - [Biological diagnosis of pituitary nanism]. PMID- 4297191 TI - [Radiotherapy in neoplasms of the parotid gland. Clinico-statistical considerations on 71 cases]. PMID- 4297192 TI - [Intense activities of lactate dehydrogenase in aerobically growing diatoms]. PMID- 4297193 TI - [On the disposal of inhaled particles]. PMID- 4297194 TI - The lecithinase (alpha toxin) activity of strains of Clostridium perfringens. PMID- 4297195 TI - The effect of glucagon and insulin on the prothrombin response to coumarin anticoagulants. PMID- 4297196 TI - Herpes-type virus recovery from "virus-free" frog kidney tumors. PMID- 4297197 TI - Plaque titration of herpes simplex with antibody-free liquid overlay. PMID- 4297198 TI - Sarocoplasmic reticulum. VI. Microsomal Ca2+ transport in genetic muscular dystrophy of mice. PMID- 4297199 TI - The effects of 6-thioguanine and endotoxin on experimental St. Louis and Japanese B encephalitis virus infections in Chiroptera. PMID- 4297200 TI - "Alveolar" and whole lung phospholipids of newborn lambs. PMID- 4297201 TI - Cortical modulation of transmission of the afferent volley through the lateral geniculate body. PMID- 4297202 TI - Resting saliva of men as a reflex. PMID- 4297204 TI - Preliminary studies on the development of a bovine parainfluenza 3 virus vaccine. PMID- 4297203 TI - Synaptic mechanism of central inhibition. PMID- 4297205 TI - [Therapeutic results in 45 cases of apparently extracorpuscular hemolytic anemia]. PMID- 4297206 TI - Contributions to the problem of the viral aetiology of certain acute nephrites in children. PMID- 4297207 TI - The biochemistry of copper. PMID- 4297208 TI - [Value of an anxiospasmolytic combination in colonic diseases and dyspepsia]. PMID- 4297209 TI - [Mucoproteinuria in radiation injuries. II. Hormonal treatment of mucoproteinuria in the experimental radiation syndrome]. PMID- 4297210 TI - [Iron storage in tissue culture and its effect on the action of diphtheria toxin and poliomyelitis virus]. PMID- 4297211 TI - Relationship between in-vitro studies of gastrointestinal muscle and motility of the alimentary tract in vivo. PMID- 4297212 TI - The response of the internal anal sphincter in man to stimulation of the presacral nerve. PMID- 4297213 TI - Medical management of chronic renal failure. PMID- 4297214 TI - Hyperplasia of the juxtaglomerular complex with secondary aldosteronism without hypertension (Bartter's syndrome). PMID- 4297216 TI - Electron paramagnetic resonance. PMID- 4297215 TI - [Relative prevalence of polioviruses in the city of Lima. (From January 1965 to January 1966)]. PMID- 4297218 TI - The four fundamental functions of the X-plasty. PMID- 4297217 TI - Glomus tympanicum tumors. PMID- 4297219 TI - The effect of temperature on the survival rate of Entamoeba histolytica (Schaudinn, 1903) cysts in water. PMID- 4297220 TI - Comparative studies of chick embryo cam cell cultures infected with variola and vaccinia viruses. PMID- 4297221 TI - [6-Years of pacemaker therapy]. PMID- 4297222 TI - [Changes in plasma ACTH activity by oral administration of SU-4485]. PMID- 4297223 TI - Studies on the role of viruses in somatic mutation. PMID- 4297224 TI - Effects of prostaglandins on adenosine 3',5'-monophosphate levels in fat and other tissues. PMID- 4297225 TI - Ethanolamine deaminase, a cobamide coenzyme-dependent enzyme. I. Purification, assay, and properties of the enzyme. PMID- 4297226 TI - The diagnosis and treatment of pigmented villonodular synovitis. PMID- 4297227 TI - A fatal illness associated with two viruses: an intermediate adenovirus type (21 16) and influenza A2. PMID- 4297228 TI - [Differential diagnosis of para-influenza and influenza]. PMID- 4297229 TI - [Theca-lutein cysts of the ovaries in normal pregnancy]. PMID- 4297230 TI - [Anatomo-clinical considerations on some cases of synovial tumors]. PMID- 4297231 TI - [Contribution to the study of the histogenesis of renal tumors induced by dimethylnitrosamine in the rat]. PMID- 4297232 TI - [An indirect method for the diagnosis of trypanosomiasis: the number of lymphocytes with PAS-positive granules in the peripheral blood]. PMID- 4297233 TI - [Study of the effect of corticosteroid hormones, ACTH and the primary antitubercular drugs on sodium and potassium metabolism in tuberculous patients]. PMID- 4297234 TI - The effects of botulinum toxin on the pattern of innervation of skeletal muscle in the mouse. PMID- 4297236 TI - [Experience in the specific prevention of infectious laryngotracheitis]. PMID- 4297237 TI - [3 cases of multiple cancer]. PMID- 4297239 TI - Nephrectomy: review of 200 cases. PMID- 4297238 TI - [Isolation and enzymatic properties of the cell membrane of Ehrlich-ascites tumor cells]. PMID- 4297240 TI - Hospital return rates and prerelease referrals. PMID- 4297241 TI - [On the fine hyperstructure of the electron spin resonance spectrum of irradiated glycine in the temperature range between 330 degrees K and 77 degrees K]. PMID- 4297242 TI - [Effect of inhibitors on changes in cytochrome oxidase activity in early development of the sea urchin]. PMID- 4297243 TI - [The reasons for lowered intensity in the metabolism of different phospholipid fractions in the rat brain under oxygen starvation of the organism]. PMID- 4297245 TI - [Detection of coenzyme Q10 in rats' mitochondria and tissues by the EPR method]. PMID- 4297244 TI - [Changes in the respiration process of vegetative tissue under gamma irradiation]. PMID- 4297246 TI - Potential health hazards of materials used by artists and sculptors. PMID- 4297247 TI - [Some complications of treatment with ACTH and corticosteroids]. PMID- 4297248 TI - [After care of irradiated genital carcinoma using the Viscum album preparation Iscador for the prevention of recurrences]. PMID- 4297249 TI - Coexistent diabetes mellitus and isolated ACTH deficiency: report of a case. PMID- 4297251 TI - [Cylindroma of the scalp]. PMID- 4297250 TI - [A giant tumor of the kidney in a child]. PMID- 4297252 TI - Cocarcinogenic effects of chemicals and radiation. BNWL-280. PMID- 4297253 TI - The reduction of reactor effluent water radionuclide concentrations by the addition of sodium silicate to process water. BNWL-235 2. PMID- 4297254 TI - [Estrogen therapy for the climacteric syndrome]. PMID- 4297255 TI - [Effect of N-isopropyl noradrenaline and phenylephrine on the retention of dust in animal experiments]. PMID- 4297256 TI - Neurohumeral factors in experimental glaucoma. PMID- 4297257 TI - [Anatomo-pathological and virological study of murine infection with encephalomyocarditis virus (Columbia-SK strain) in otorhinolaryngology]. PMID- 4297258 TI - [The use of angiotensin II in surgical treatment of pheochromocytoma]. PMID- 4297259 TI - Tartaric acid metabolism. 3. The formation of glyceric acid. PMID- 4297260 TI - Tartaric acid metabolism. IV. Crystalline L-malic dehydrogenase from Pseudomonas acidovorans. PMID- 4297261 TI - Tartaric acid metabolism. V. Crystalline tartrate dehydrogenase. PMID- 4297262 TI - The isolation of an antimycin-resistant mutant of orulopsis utilis. PMID- 4297263 TI - Studies on dihydroorotate dehydrogenase by electron paramagnetic resonance spectroscopy. II. Electron paramagnetic resonance and optical spectra and titrations. PMID- 4297264 TI - Studies on dihydroorotate dehydrogenase by electron paramagnetic resonance spectroscopy. 3. Kinetic studies by rapid freezing. PMID- 4297265 TI - Chemical characterization of D-lactate dehydrogenase from Escherichia coli B. PMID- 4297266 TI - Kinetics of Escherichia coli B D-lactate dehydrogenase and evidence for pyruvate controlled change in conformation. PMID- 4297267 TI - Effects of various salts on the binding of indole compounds with bovine albumin. PMID- 4297268 TI - Biosynthesis of a bacterial lipopolysaccharide. VI. Mechanism of incorporation of abequose into the O-antigen of Salmonella typhimurium. PMID- 4297270 TI - Metallo-enzymes released from Escherichia coli by osmotic shock. II. Evidence that 5'-nucleotidase and cyclic phosphodiesterase are zinc metallo-enzymes. PMID- 4297269 TI - Metallo-enzymes released from Escherichia coli by osmotic shock. I. Selective depression of enzymes in cells grown in the presence of ethylenediaminetetraacetate. PMID- 4297271 TI - Prufication and properties of D-fructose 1,6-diphosphatase from swine kidney. PMID- 4297272 TI - Role of enzyme-enzyme interactions in the regulation of glycolysis. Inactivation of D-fructos 1,6-diphosphatase by kidney cortex mitochondria. PMID- 4297273 TI - Magnetic resonance studies on inactivated forms of creatine kinase. PMID- 4297274 TI - Cleavage of cholesterol side chain associated with cytochrome P-450, flavoprotein, and nonheme iron-protein derived from the bovine adrenal cortex. PMID- 4297275 TI - [19. Cortisone premedication and abdominal surgery]. PMID- 4297276 TI - [20. Clinical and experimental data on wound healing following corticoid administration]. PMID- 4297277 TI - [32c. Endocrine related consciousness disorders following surgery]. PMID- 4297278 TI - [73. Osteoradionecrosis of the hip joint and possibilities in its management]. PMID- 4297279 TI - [Therapeutic possibilities in cylindromatous tumors of the maxillary sinus]. PMID- 4297280 TI - [The clinical aspects of complications of steroid therapy and their presentation]. PMID- 4297281 TI - [Assessment of the function of the adrenal glands in nephritis and its corticosteroid therapy]. PMID- 4297282 TI - Continuing care--the relationship between the acute medical center and community resources. PMID- 4297283 TI - Fetal alpha-globulin of bone serum differing from fetuin. PMID- 4297284 TI - [Silicic acid in metabolism]. PMID- 4297285 TI - Hormonal control of ketosis in the chronically hypophysectomized, pancreatectomized rat. PMID- 4297286 TI - The mechanism of action antilipolytic agents: a comparison of the effects of PGE1, insulin, tolbutamide, and phenformin on lipolysis induced by dibutryl cyclic AMP. PMID- 4297287 TI - Effect of imidazole upon insulin secretion. PMID- 4297288 TI - An outbread of pox in chimpanzees. PMID- 4297289 TI - Neoplasms of ducks in Andhra Pradesh. II. A report of four intra-hepatic tumours. PMID- 4297290 TI - Entrapment neuropathy of the central nervous system. II. Cranial nerves I-IV, VI VIII, XII. PMID- 4297291 TI - Clinical and laboratory findings in patients with hepatoma: a preliminary report. PMID- 4297292 TI - [Fructose diphosphate phosphatase as a metabolic regulator of glyconeogenesis]. PMID- 4297293 TI - The effect of caesium ions of neuromuscular transmission in the frog. PMID- 4297294 TI - Virus-directed protein synthesis in different animal and human cells. AB - The relative proportions of viral gene products (viral proteins) that are synthesized in different types of animal cells infected with the same RNA virus inoculum were compared. The relative rates of synthesis of the various virus proteins late in infection were remarkably constant regardless of cell type infected. This was true in cell lines that produced only small amounts of virus and virus proteins, as well as in those that gave large yields of viruses and virus proteins. PMID- 4297295 TI - Diagnosis of granular cell myoblastoma by fine-needle aspiration biopsy. PMID- 4297296 TI - Metabolism of cholic acid in germfree animals after the establishment in the intestinal tract of deconjugating and 7 alpha-dehydroxylating bacteria. PMID- 4297297 TI - Fatal varicella generalisata in a child with immunopathy and neurological retardation. PMID- 4297298 TI - Properties of the rough microsomes. PMID- 4297299 TI - The effect of some cancer-therapeutic agents on the transplantability and growth of an SV40 sarcoma in rat. PMID- 4297300 TI - The ultrastructure of normal and pathological IgM immunoglobulins. PMID- 4297301 TI - Replication of poliovirus RNA studied by gelfiltration. PMID- 4297302 TI - [Recent data on the therapy of sinusitis]. PMID- 4297303 TI - [The kidney tumor risk in the aniridic child]. PMID- 4297304 TI - [The effect of ACTH on the function of the thyroid gland in young rabbits in injury to and regeneration of the skeletal musculature]. PMID- 4297305 TI - A case of cylindroma of the mandible. PMID- 4297306 TI - Enzymatic determination of creatine in serum and cerebrospinal fluid. PMID- 4297307 TI - Determination of unconjugated etiocholanolone in human plasma using gas-liquid chromatography. PMID- 4297308 TI - The influence of hemolysins on the ATPase activity and the composition of the erythrocte membrane. PMID- 4297309 TI - [Research on the excretion of urinary homogentisic acid by heterozygotes for alkaptonuria]. PMID- 4297311 TI - P Persistence of enzymatic activities in stored and geologically preserved soils. PMID- 4297310 TI - Enzymatic decrease of NADH2 in the presence of gamma-glutamylhydroxamic acid. PMID- 4297312 TI - [Simultaneous excision of the stomach and gynecologic organs in a case of Krukenberg's cancer]. PMID- 4297313 TI - Complications in cattle following vaccination with a combined bovine viral diarrhea-infectious bovine rhinotracheitis vaccine. PMID- 4297314 TI - Pathogenesis and pathology of infection in calves with strains of reovirus types 1 and 2. PMID- 4297316 TI - [Mixed tumor of the soft palate and secondary epithelioma]. PMID- 4297315 TI - Pathogenesis and pathology in calves of infection by Bedsonia alone and by Bedsonia and reovirus together. PMID- 4297317 TI - Continuous culture of mixed populations. PMID- 4297318 TI - Synergistic action of polysorbate 80 and polymyxin B sulphate on Pseudomonas aeruginosa. PMID- 4297319 TI - The fine structure of wound repair in an insect (Rhodnius prolixus). PMID- 4297320 TI - Quantitative determination of some synthetic antiparkinsonism agents. PMID- 4297321 TI - Stability of diosgenin. PMID- 4297322 TI - Determination of free salicylic acid in buffered aspirin tablets. PMID- 4297323 TI - Separation and determination of polymyxin B in formulations. PMID- 4297324 TI - Quantitative determination of diethylstilbestrol by thin-layer chromatography. PMID- 4297325 TI - Antitumor agents from Bursera microphylla (Burseraceae) I. Isolation and characterization of deoxypodophyllotoxin. PMID- 4297326 TI - Inhibition in IA inhibitory pathway by impulses in recurrent motor axon collaterals. PMID- 4297327 TI - The effects of prostaglandins E1 and E2 on ovarian steroidogenesis. PMID- 4297328 TI - [Central and peripheral neural symptoms of causative systemic lupus erythematosus]. PMID- 4297329 TI - Effects of hydration and dehydration on cyclic adenosine 3',5'-monophosphate concentration in the rat kidney. PMID- 4297330 TI - Electron spin resonance of a gamma-irradiated single crystal of 3'-cytidylic acid. PMID- 4297331 TI - The synthesis of collagen and protocollagen hydroxylase by fibroblastic and nonfibroblastic cell lines. PMID- 4297332 TI - Loss of T-antigen from somatic hybrids between mouse cells and SV40-transformed human cells. PMID- 4297333 TI - Viral DNA in polyoma- and SV40-transformed cell lines. PMID- 4297334 TI - Effect of bretylium and guanethidine on transmission to sweat glands in the cat. PMID- 4297335 TI - The chelate structure of Micrococcus aerogenes rubredoxin. PMID- 4297336 TI - Cyclic adenosine monophosphate, CA++, and membranes. PMID- 4297337 TI - Specific inhibition of virus growth in cells treated with phospholipase C. PMID- 4297338 TI - [Histoenzymologic studies of the caudal neurosecretory system of Cyprinus carpio L]. PMID- 4297339 TI - Histoenzymatic study of the tongue mucosae in different species. PMID- 4297341 TI - [Electron microscopic histochemistry of nucleoside phosphatases of the retina. II. Fine structural localization of nucleoside phosphatases and other phosphatases of the retina]. PMID- 4297340 TI - A chromatographic analysis of the lipid of cat and dog kidneys. PMID- 4297342 TI - The African custom of tooth mutilation in America. PMID- 4297343 TI - [Influence of stresses on the plasma potassium and sodium levels in the pregnant and nonpregnant rat and in the fetus]. PMID- 4297344 TI - [Stability of aqueous penicillin solutions]. PMID- 4297345 TI - The effect of irradiation on the cultured human leucocytes with special reference to the survival after large doses. PMID- 4297346 TI - Radioautographic study on RNA labeling in rat liver parenchyma during DAB carcinogenesis. PMID- 4297347 TI - The induction of benign and malignant liver tumors by urethan in newborn rats. PMID- 4297348 TI - The relationship of hepatoma in rainbow trout to aflatoxin contamination and cottonseed meal. PMID- 4297349 TI - [Hormone-producing tumors]. PMID- 4297350 TI - [Radioimmunoassay of hormones]. PMID- 4297351 TI - [Comparative vasographic and scintigraphic studies in liver tumors]. PMID- 4297352 TI - [Histochemical studies on intracellular glycogen metabolism in AH l3 ascites tumor cells. 1. Autoradiographic study on the AH l3 cell cycle]. PMID- 4297353 TI - [Histochemical studies on intracellular glycogen metabolism in AH 13 ascites tumor cells. 2. AH 13 cell cycle and intracellular reaction of glycogen, phosphorylase and UDPG-glycogen glucosyltransferase]. PMID- 4297354 TI - [Histochemical studies on intracellular glycogen metabolism in AH 13 ascites tumor cells. 3. Autoradiographic study on RNA synthesis in the AH-13 cell and intracellular glycogen in the cell cycle]. PMID- 4297355 TI - [Radiotherapy of kidney neoplasms in children]. PMID- 4297357 TI - [Problems in the outpatient CARE OF MENTAL DISORDERS]. PMID- 4297356 TI - [Radiotherapeutic problems in childhood]. PMID- 4297358 TI - [Effect of angiotensin and vasopressin on the vascular territory of the mesentery dependant on vascular tone in the dog]. PMID- 4297359 TI - [The effect of placental gonadotropic hormones on the genital organs of hypophysectomized infantile female rats]. PMID- 4297362 TI - Ulcerogenic tumor of the pancreas diagnosed preoperatively by bioassay. PMID- 4297360 TI - The foetal adrenal cortex in the human. Its ultrastructure at different stages of development and in different functional states. PMID- 4297363 TI - Unusual locations and manifestations of glomus tumors (glomangiomas). PMID- 4297364 TI - Can breast carcinoma be anticipated? A follow-up of benign breast biopsies. PMID- 4297365 TI - Bronchial adenoma. PMID- 4297366 TI - On the theory of silicosis. IV. The topochemical interaction. PMID- 4297367 TI - Role of silica in progressive massive fibrosis. In coal workers' pneumoconiosis. PMID- 4297369 TI - Chemical biology of in vivo and in vitro wounds. PMID- 4297368 TI - Successful metyrapone therapy of the ectopic ACTH syndrome. PMID- 4297370 TI - Proteases and antiproteasic substances in the inflammatory response. PMID- 4297371 TI - Heparin: molecular weight and degradation studies. PMID- 4297374 TI - Sialic acid contents and controls of normal and malignant cells. PMID- 4297375 TI - Fasting in obese females. II. Plasma renin activity and urinary aldosterone. PMID- 4297372 TI - Liver microsomal inorganic pyrophosphate-glucose phosphotransferase: alterations in activity-pH profiles by cortisone in vivo. PMID- 4297376 TI - Virology in a general hospital. PMID- 4297373 TI - On the reversibility of the first segment of glycolysis in ascites tumor cells. PMID- 4297377 TI - Friedlander's pneumonia. A report of 11 cases and appraisal of antibiotic therapy. PMID- 4297378 TI - Biological studies on an anti-androgen (SH 714). PMID- 4297380 TI - Estrogens and gastric secretion. PMID- 4297379 TI - Comparative enzyme histochemistry of immature and mature stages of Fasciola hepatica. PMID- 4297381 TI - Effect of phytohemagglutinin on ascites tumor and SV40 induced sarcoma of hamsters. PMID- 4297382 TI - Physical chemical properties of SV40 induced tumor ("T") antigen. PMID- 4297383 TI - Inhibitory effect of hypothalamic implants of corticosterone on adrenocortical response to auditory stimulation. PMID- 4297384 TI - Rapid liberation of potassium ions from brain mitochondria. PMID- 4297385 TI - Studies on the mechanism of action of the adrenocorticotropic hormone in fat mobilization. PMID- 4297386 TI - Visualization of acyl phosphatase after zone electrophoresis and thin-layer gel filtration. PMID- 4297387 TI - Natural fatal infection of an owl monkey (Aotus trivirgatus) with Herpes T virus. PMID- 4297388 TI - Intervertebral discolysis with collagenase. PMID- 4297389 TI - Diagnosis and treatment of entrapment neuropathies. PMID- 4297390 TI - Studies on poliovirus inhibitors in sera of domestic animals. I. Distributions and properties of poliovirus inhibitors in bovine and equine sera. PMID- 4297391 TI - Investigative studies with quartz rods for high energy laser transmission. PMID- 4297392 TI - Peripheral nerve injuries--diagnosis and treatment. PMID- 4297393 TI - Morphology and development of viruses in mammary carcinoma of mice. PMID- 4297394 TI - Biological membranes: regulatory functions. PMID- 4297395 TI - Preoperative radiation. PMID- 4297396 TI - Adrenocortical response to craniocerebral trauma. PMID- 4297397 TI - The effect of transient renal anoxia and portacaval transposition on canine arterial blood pressure. PMID- 4297398 TI - Ulcerative colitis in the elderly patient. PMID- 4297399 TI - Tumorigenicity of the antigen-forming defective virions of imian virus 40. PMID- 4297400 TI - Effect of magnesium trisilicate on the infectivity of tobacco mosaic virus. PMID- 4297401 TI - Recovery of SV40 virus with genetic markers of original inducing virus from SV40 transformed mouse cells. PMID- 4297402 TI - The effect of polycations on the interaction of viral RNA with mammalian cells: studies on the infectivity of single- and double-stranded poliovirus RNA. PMID- 4297403 TI - Virus isolations from children with acute respiratory illness. A comparison of a family study group and a group of nursery infants. PMID- 4297404 TI - Parasitic serologic studies in Somaliland. PMID- 4297405 TI - Simian hemorrhagic fever. 3. Isolation and characterization of a viral agent. PMID- 4297406 TI - Further studies of the Xavante Indians. IX. Immunologic status with respect to various diseases and organisms. PMID- 4297408 TI - Systemic herpes simplex infection in a newborn treated with intravenous idoxuridine. PMID- 4297407 TI - Plasma cortisol levels in protein-calorie malnutrition. PMID- 4297409 TI - Influence of growth hormone on results of allergization in guinea pigs. PMID- 4297411 TI - Glomus tumour of palate. PMID- 4297410 TI - [Adult Wilm's tumor of the kidney]. PMID- 4297412 TI - Deja vu--as related to diagnostic categories in psychiatric and neurosurgical patients. PMID- 4297413 TI - Localisation of human placental factor in malignant teratoma of testis. PMID- 4297414 TI - A case of renal dysplasia and relation to "bilateral nephroblastomatosis". PMID- 4297415 TI - The effects of bradykinin, angiotensin and acetylcholine on the bovine adrenal medulla. AB - 1. The response of the adrenal medulla to the intra-arterial injection of angiotensin, bradykinin and acetylcholine and to splanchnic nerve stimulation has been investigated in day-old and 3- to 18-month-old calves and in adult cats.2. Bradykinin and angiotensin had no appreciable effect on catecholamine release in the day-old calf nor did these peptides potentiate the response of the gland to acetylcholine.3. In older calves the response of the gland to bradykinin and angiotensin was marginally above the control output, whereas acetylcholine and splanchnic nerve stimulation caused a 10-100 fold increase in the rate of secretion. The response to acetylcholine but not to the peptides was related to the dose administered.4. The adrenal medulla of the cat was stimulated by angiotensin and bradykinin but the maximum amounts released by the peptides were much smaller than the discharge elicited either by splanchnic nerve stimulation or by acetylcholine. No dose-response relationship could be found for either adrenaline or noradrenaline released by angiotensin, or for noradrenaline released by bradykinin. The slight increase in adrenaline output which followed the injection of bradykinin was dependent on the dose but the slope of the curve (b = 0.161) was much less than that for acetylcholine (b = 0.636). PMID- 4297416 TI - The effect of oestrogen and progesterone on the pressor action of angiotensin in the rat. AB - 1. A comparison was made between the pressor responses to angiotensin in rats during different stages of the oestrous cycle, pregnancy, pseudopregnancy and also following oestrogen and progesterone treatment.2. No evidence for an effect of oestrogen on the response to angiotensin was found.3. Pregnancy and pseudopregnancy were found to diminish the pressor response to angiotensin.4. Progesterone treatment also diminished the response to angiotensin.5. It is suggested that the decrease in pressor response in pregnancy and pseudopregnancy is attributable to progesterone.6. The possible mode of action of progesterone is discussed. PMID- 4297418 TI - Electrical activity observed in guinea-pig olfactory cortex maintained in vitro and its modification by changes in the ionic composition of the bathing medium. PMID- 4297419 TI - Anti-microbial drugs in animal feeds. PMID- 4297417 TI - Termination and functional organization of the ventral spino-olivocerebellar path. AB - 1. The spino-olivocerebellar path ascending through the ventral funiculus (VF SOCP) was investigated in decerebrate cats with the cord transected in the third cervical segment except for the left ventral funiculus. The climbing fibre responses evoked in Purkinje cells were studied by recording from single cells and by recording the mass activity at the cerebellar surface or in the molecular layer.2. In the spinal cord the forelimb component of the VF-SOCP occupies a medial part and the hind limb component a lateral part of the ventral funiculus.3. The main projection of the limb nerves through the VF-SOCP is to the lateral two thirds of the vermis of the anterior lobe. The projection area consists of three sagittally arranged bands: a lateral band receiving olivary axons activated exclusively from the ipsilateral hind limb, an intermediate band receiving olivary axons activated bilaterally from the hind limbs, and a medial band receiving olivary axons activated bilaterally from the forelimbs. Some olivary neurones are activated from all four limbs.4. The latency of the climbing fibre responses was about 22 msec on stimulation of ipsilateral hind limb nerves and about 20 msec on stimulation of ipsilateral forelimb nerves. The responses evoked from contralateral nerves had a latency which was about 3 msec longer than the latency of the corresponding ipsilateral responses.5. The olivary neurones were usually activated from all tested muscle and skin nerves in the limb(s) constituting the receptive field. Cutaneous afferents and groups II and III muscle afferents were responsible for the excitation elicited by single shock stimulation of the nerves. Brief repetitive stimulation revealed additional activation from mainly Ib, but also Ia, afferents in ipsilateral hind limb nerves.6. Natural stimulation of receptors evoked responses in about half of the olivary neurones tested. The responses were elicited by strong pressure against deep structures. Inhibitory effects were seldom observed. PMID- 4297420 TI - Virus etiologic studies of human leukemia. PMID- 4297421 TI - Neurologic manifestations and complications of lymphoma. PMID- 4297422 TI - [Recurrent oral ulceration]. PMID- 4297423 TI - [Malignant hepatoma with splenic metastasis]. PMID- 4297424 TI - [Comparative studies of urinary steroids in pemphigus]. PMID- 4297425 TI - [Clinical study on the conduction velocity of peripheral motor nerves]. PMID- 4297426 TI - [Membrane properties and neuromuscular transmission of obliquely-striated muscle]. PMID- 4297427 TI - [Effect of nystatin, trichomycin and levorin on the growth of human parasitic intestinal Protozoa in cultures]. PMID- 4297428 TI - [A simple method for the preparation of high grade complement fixing enterovirus antigen]. PMID- 4297429 TI - [Histochemical study of some enzymes in the hypertrophied myocardium in experimental renal hypertension]. PMID- 4297430 TI - [Biochemistry of energy metabolism and its disorders in vertebrate embryos]. PMID- 4297431 TI - [Phasic and tonic components in the pyramidal effects on motor neurons]. PMID- 4297432 TI - [On myoblastic myoma of the eye]. PMID- 4297433 TI - [Contribution to the differential diagnosis of virilism from clinical aspects of a case of hypernephroid ovarian tumor]. PMID- 4297434 TI - [Changes in plasma phospholipids in acute hepatitis]. PMID- 4297435 TI - Neutron activation analysis of potassium in biologic material with the use of a new separation method . PMID- 4297436 TI - [On the classfication a5blagoveshchenskaia NS, Vaishenker PG, Bal'sevich SI, Garbuzov MI: [On the classification of glomus tumors of the middle ear as a function of localization and the direction of their growth]. PMID- 4297437 TI - [The activity of acetylation processes and lipid metabolism in children with eczema]. PMID- 4297438 TI - [Differential anaomopathologic diagnosis of influenza and adenovirus infection]. PMID- 4297440 TI - [Present possibilities of cytodiagnosis]. PMID- 4297439 TI - [Excretion and metabolism of dehydroepiandrosterone in the newborn]. PMID- 4297441 TI - [Demonstration of Bordetella pertussis antibodies by the latex slide test in comparison to agglutination and complement fixation test]. PMID- 4297442 TI - [Sodium desoxycholate extract according to Barta from Bordetella pertussis as an antigen for the serological antibody demonstration in the complement fixation reaction and in latex slide test]. PMID- 4297443 TI - [The effect of adrenal gland extirpation and corticoid therapy on serum heparin content]. PMID- 4297445 TI - O: Renin-angiotensin system in normal and toxemic pregnancies. IV. Inactivation of angiotensin in toxemic pregnancy. PMID- 4297444 TI - Cytological features of viral respiratory tract infections. PMID- 4297446 TI - Kidney. PMID- 4297447 TI - Regulation of the adenohypophysis. PMID- 4297449 TI - Oculocutaneous metastases from carcinoma of the urinary bladder. Case report and review of the literature. PMID- 4297448 TI - Solid-cystic hidradenoma of the skin. Clinical and histopathologic study. PMID- 4297450 TI - Environmental carcinogens. PMID- 4297451 TI - Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. I. Neurologic, genetic, and electrophysiologic findings in hereditary polyneuropathies. PMID- 4297453 TI - [Attempted transplantation of Yoshida's ascites hepatoma into the articular cavity in the rat]. PMID- 4297452 TI - Neuromuscular changes with alloxan hyperglycemia. Electrophysiological, biochemical, and histological study in rats. PMID- 4297454 TI - Antibiotic topical spray in a simulated combat wound. II. Neomycin-bacitracin polymyxin B, and penicillin. PMID- 4297457 TI - The Doman-Delcato treatment of neurologically handicapped children. PMID- 4297456 TI - Intracranial tumours in infancy. PMID- 4297455 TI - [Stereotaxic hypophyseal implantation of yttrium 90 by a transorbital approach. Technic and results]. PMID- 4297458 TI - A method of preparing adrenal cell suspensions and its applicability to the in vitro study of adrenal metabolism. PMID- 4297459 TI - Suppression of pituitary gland hormone content by pituitary tumor hormones. PMID- 4297460 TI - Inhibition of inosine monophosphate-dehydrogenase by thyroid hormones in vitro. PMID- 4297462 TI - Avian helper cell and its role in the in vitro transfer of Rous virus (Prague strain) genome from rat tumour cells to chick cells. PMID- 4297463 TI - Viral group specific antigen in mammalian Rous tumours detected by complement fixation and fluorescent antibody tests. PMID- 4297461 TI - Effects of steroids and ACTH on pyruvate and acetate metabolism by the sheep adrenal cortex in vitro. PMID- 4297464 TI - Minute chromatin bodies in two mouse tumours induced in vivo by Rous sarcoma virus. PMID- 4297465 TI - The energy-linked incorporation of diphosphopyridine nucleotide into rat liver mitochondria. Requirements for incorporation. PMID- 4297466 TI - Allosteric properties of nucleoside diphosphatase and its identity with thiamine pyrophosphatase. PMID- 4297467 TI - Biosynthesis of mannophosphoinositides by Mycobacterium phlei. Enzymatic acylation of the dimannophosphoinositides. PMID- 4297468 TI - On the mechanism of phenethyl alcohol-induced loss of polyribosomes and their re formation after reversal in rat hepatoma cells. PMID- 4297469 TI - The metal complexes of peptides and related compounds. 3. Copper(II) complexes of glycylglycylglycine in 3.0 M (Na)ClO4 medium. PMID- 4297470 TI - Kinetic studies on the inhibition of a (D(-)-specific lactate dehydrogenase by adenosine triphosphate. PMID- 4297471 TI - Participation of aminoacyl transfer ribonucleic acid in aminoacyl phosphatidylglycerol synthesis. II. Specificity of alanyl phosphatidylglycerol synthetase. PMID- 4297472 TI - Respiratory activity of intact, isolated parenchymal cells from rat liver. PMID- 4297474 TI - A new enzyme with the glycolytic function of pyruvate kinase. PMID- 4297473 TI - Structural studies on nicotinamide adenine dinucleotide-linked L-glycerol 3 phosphate dehydrogenase crystallized from rat skeletal muscle. PMID- 4297475 TI - Adrenal hyperplasia--a case report of delayed onset of the congenital form or an acquired form. PMID- 4297476 TI - Effect of dexamethasone on ACTH release induced by lysine vasopressin in man; time interval between dexamethasone and vasopressin injection. PMID- 4297477 TI - Metabolic fate of histidylleucine, a metabolite of angiotensin I. PMID- 4297478 TI - Sites of action of sodium depletion on aldosterone biosynthesis in the dog. AB - Secretion of cortisol, corticosterone, and aldosterone was measured in vivo in normal and sodium-depleted hypophysectomized dogs. Biogenesis of steroids was then measured in vitro with outer slices of the adrenals of the same dogs. In some studies, metyrapone or puromycin was added. In vivo, sodium depletion stimulated the production of cortisol, corticosterone, and aldosterone. In vitro, tissues from sodium-depleted animals released more aldosterone, but less corticosterone than those from sodium-replete controls. The results are interpreted to indicate that (a) biosynthesis of aldosterone is regulated at at least two sites in the biosynthetic pathway. The final conversion, that of corticosterone to aldosterone, is stimulated by sodium depletion. This effect persists for at least 3 hr while slices from sodium-depleted dogs are incubated in vitro. Stimulation at this site is thus relatively stable in vitro; its activation by sodium depletion is not inhibited by puromycin in the dog. Stimulation at this site can explain, at least in part, the increased effectiveness of adrenocorticotropin (ACTH) on aldosterone biogenesis during sodium depletion.(b) the earlier site at which sodium depletion stimulates the secretion of aldosterone is "above" the position of desoxycorticosterone in the pathway; it is probably at the conversion of cholesterol to pregnenolone. Stimulation at this site is quickly lost during incubation of adrenal slices. It is thus relatively unstable in vitro; its activation by sodium depletion is inhibited by puromycin in the dog. PMID- 4297479 TI - Studies on the mode of action of diphtheria toxin. VI. Site of the action of toxin in living cells. AB - Using the technique of radioautography, it has been shown that a probable maximum of only 25-50 molecules iodine-125-labeled toxin per cell is bound by human HeLa cells treated with approximately 10(7) molecules of toxin per cell, or just under one saturating dose. Radioautographs of sections from labeled cells locate most if not all of the toxin molecules fixed to the outer cell membrane. Under identical conditions far less label is taken up by mouse L cells. It is probable that the resistance of this species to diphtheria toxin can be accounted for in terms of the failure of mouse cells to bind the toxin protein. The irreversible inhibition of protein synthesis in a living cell culture by a few molecules of toxin located at the cell surface is discussed in relation to the known interaction between toxin, NAD, and transferase II in mammalian cell extracts. PMID- 4297480 TI - Thiamine monophosphate, a normal constituent of rat plasma. PMID- 4297481 TI - Effect of calcium and vitamin D3 upon the fecal excretion of some metals in the mature male rat fed a high fat, cholesterol diet. PMID- 4297482 TI - Schistosomal granuloma with muco-epidermoid carcinoma of parotid gland. PMID- 4297483 TI - Soft-tissue sarcomas of infants and children: a clinicopathologic study of 135 cases. PMID- 4297484 TI - [Lack of carcinogenic effect of photolyzed diethylnitrosamine]. PMID- 4297485 TI - Herpes simplex encephalitis: report of two fatal cases in Singapore. PMID- 4297486 TI - [Rat deciduoma and "chemical splenectomy" using ethylpalmitate]. PMID- 4297487 TI - Atypical adrenal hyperfunction: in vivo studies and incubations of adrenal tissue with 4-14C progestrone. PMID- 4297488 TI - [Storage of actinomycetes]. PMID- 4297490 TI - [Comparative study of the clearance of blood serum from kanamycin and florimycin (viomycin) in rabbits]. PMID- 4297489 TI - [Use of ristomycin during the selection of active variants of Proactinomyces fructiferi var. ristomycini]. PMID- 4297491 TI - [Antiviral activity of the antibiotic rubomycin]. PMID- 4297492 TI - [Determination of the sensitivity of acidophilic bacteria toward antibiotics and furazolidone]. PMID- 4297494 TI - [Specific anti-herpetic vaccination. Personal results]. PMID- 4297493 TI - The electron spin resonance spectra of chemically modified lysozyme irradiated in the solid state. PMID- 4297495 TI - [Bullous toxicoderma (bullous allergoderma) after sulfamide-retard (associated with profuse herpes)]. PMID- 4297496 TI - [Cytochemical studies of mouse embryo cells in early stages of infection with oncogenic polyoma virus]. PMID- 4297497 TI - Functioning of the hypothalamo-pituitary-adrenal system during postnatal development in rats. PMID- 4297498 TI - Morphological changes in the hypothalamo-pituitary-adrenal system during early postnatal period in rats. PMID- 4297499 TI - The effect of corticosteroid concentrations in the blood of gravid rats on the adrenocorticotropic function of hypophysis of the fetus. PMID- 4297500 TI - Histostructure of adenohypophysis of human fetuses and contents of somatotropic and adrenocorticotropic hormones. PMID- 4297501 TI - Collagenases in mammalian cells. PMID- 4297502 TI - Observations on the use of live and inactivated virus vaccines against sheep pox. PMID- 4297503 TI - A successfully treated case of Pseudomonas endocarditis, with review of the literature. PMID- 4297504 TI - [Histology of lid tumors with special consideration of juvenile melanoma (Spitz) and hidradenoma papilliferum]. PMID- 4297505 TI - [On the therapy of dacryostenosis in the clinic and in practice]. PMID- 4297506 TI - [Studies of the effect of synthetic angiotensin II on blood sugar levels in persons with manifest and latent diabetes mellitus]. PMID- 4297508 TI - [Chronophysiology and chronopathology]. PMID- 4297507 TI - [Hormones and cancer]. PMID- 4297509 TI - [Surgery of the adrenal gland]. PMID- 4297511 TI - [Nil nocere'. Generalized fatal varicella during high-dosage corticosteroid therapy. Report of 2 cases]. PMID- 4297510 TI - [Glucocorticoids and serum calcium content]. PMID- 4297512 TI - [Notice of two cultures and a biopsy of Burkitt's tumor seen under the electron microscope]. PMID- 4297513 TI - [Removable orthodontic appliance in relation to the phosphomonoesterase activity in the gingival mucosa]. PMID- 4297514 TI - [The effect of isologous cells on the servival and growth of ascitic hepatoma 22]. PMID- 4297515 TI - [Gonadal tumors in women with negative sex chromatin]. PMID- 4297516 TI - [Transformation of guinea pig and golden hamster embryo cello by Rous virus]. PMID- 4297517 TI - [Malignization of adenomatous tumors of the epididymis]. PMID- 4297518 TI - [On the incidence and prognosis of malignant tumors in children]. PMID- 4297519 TI - [The effect of nicotinic acid and propranolol on the lipolytic action of catecholamines and peptide hormones in vitro]. PMID- 4297520 TI - [On hematogenous metastazing of nasal and paranasal sinus carcinoma]. PMID- 4297521 TI - Some observations on hydrolysis of oestrogen conjugates in bovine urine. Formation of oestratetraenol. PMID- 4297522 TI - Hepatorenal syndrome. A review. PMID- 4297523 TI - Compression of the posterior tibial nerve. (The tarsal tunnel syndrome). PMID- 4297524 TI - Enzymic synthesis of vitamin B 12. PMID- 4297525 TI - Enzyme localization in the inner and outer mitochondrial membranes. PMID- 4297526 TI - The possible failure of 15N to affect fhe ESR spectrum of the non-heme iron proteins of Azotobacter vinelandii. PMID- 4297527 TI - Lysis of spheroplasts of Escherichia coli by a non-ionic detergent. PMID- 4297528 TI - Pseudo-allosteric behavior of firefly luciferase. PMID- 4297529 TI - Changes of plasma renin concentration during pressor infusions of renin in the conscious dog: the influence of dietary sodium intake. PMID- 4297530 TI - Chemoreception and efferent sensory impulses in Lumbricus terrestris Linn. PMID- 4297531 TI - Biochemical studies of purine catabolism in Ceratitis capitata. PMID- 4297532 TI - On the phospholipids of Ascaris lumbricoides. PMID- 4297533 TI - Immunochemical studies on Salmonella. 13. Chemical changes appearing on the specific polysaccharide of S. cholerae suis (6-2,7) after its conversion by phage 14(6,7). PMID- 4297534 TI - Pulsed incorporation of 32P by the soluble oscillating glycolytic system from Saccharomyces carlsbergensis. PMID- 4297535 TI - Somatic afferent input to posterior thalamic neurones and their axon projection to the cerebral cortex in the cat. AB - 1. A technique of reversible block of synaptic transmission through the dorsal column nuclei and the trigeminal nucleus caudalis (n. caudalis) has been employed to assess the somatic afferent input to individual posterior thalamic neurones in the cat. The axon projection to the cerebral cortex of these neurones has been identified by antidromic activation following cortical stimulation.2. Unitary responses in the nucleus ventralis posterolateralis (VPL) evoked by cutaneous stimulation were abolished or depressed following block of transmission in the dorsal column nuclei. Block in n. caudalis, however, depressed unitary responses in nucleus ventralis posteromedialis (VPM) evoked by facial skin stimulation in less than 10% of cells.3. A more complex source of the somatic input to the posterior nuclear region of the thalamus (PO) was found. It was most commonly noted that PO unitary activity evoked by cutaneous stimulation of the face was unaffected by block of synaptic transmission in n. caudalis. No uniform effect was observed on unitary responses in PO evoked by limb stimulation when transmission in the dorsal column nuclei was blocked.4. Antidromic activation from the cerebral cortex was seen in 69% of ventrobasal neurones. Most cells (66%) had ;antidromic cortical fields' restricted to a region consisting of a third to a half of the specific somatic projection areas. In 10% of cells evidence was obtained for discontinuous cortical ;antidromic fields' suggesting subcortical bifurcation of the projecting axon.5. An axon projection to the cortex was found in 35% of PO cells, about half of which projected only to specific somatic projection areas. Evidence for subcortical branching of the axon was obtained for seven PO cells. PMID- 4297536 TI - Frequencygrams of spindle primary endings elicited by stimulation of static and dynamic fusimotor fibres. AB - 1. Frequencygrams of cat spindle primary endings, obtained by the method described by Bessou, Laporte & Pages (1968), were elicited by the stimulation of single static and dynamic fusimotor fibres.2. Stimulation of static fibres by single stimuli may elicit: (i) no response, (ii) responses of small amplitude, (iii) responses of large amplitude with a pause after the rising phase.3. Stimulation of static fibres by repetitive stimuli gives frequencygrams resembling records of tetanic contraction of skeletal muscle. At a frequency of stimulation of 180-200/sec periodic oscillations are perceptible on the plateau of the frequencygram.4. Stimulation of dynamic fibres by single stimuli may elicit: (i) no response, (ii) responses smaller and longer than the responses given by static fibres.5. When the muscle is stretched the amplitude of the responses elicited by dynamic fibres decreases whereas the amplitude of the responses given by static fibres increases.6. Frequencygrams obtained by repetitive stimulation of dynamic fibres show periodic oscillations only at low rates of stimulation. At rates of stimulation higher than the minimal rate giving frequencygrams with a smooth contour, the amplitude of the frequencygram increases. PMID- 4297537 TI - On the mechanism by which calcium and magnesium affect the release of transmitter by nerve impulses. AB - 1. The relationship between the quantal content of end-plate potentials (e.p.p.s) and the bathing [Ca] and [Mg] was determined at neuromuscular junctions in the rat diaphragm in vitro.2. E.p.p.s were recorded intracellularly from preparations exposed to solutions with [Ca] between 0.05 and 10 mM and [Mg] between 0.1 and 12.5 mM. The quantal content of e.p.p.s was increased by raising the [Ca] over this range and decreased by raising the [Mg]. There appeared to be competition of Mg with Ca at three sites in the nerve terminal membrane.3. A kinetic scheme based on competition of Ca and Mg at three sites could quantitatively explain the effects of Ca and Mg upon the quantal content of e.p.p.s and also the effects of these ions upon miniature end-plate potential frequency. PMID- 4297538 TI - Electron microscopy of siliceous spicules from the freshwater sponge Heteromyenia. PMID- 4297539 TI - Bilateral diffuse Wilms tumor: a 5-year survival. PMID- 4297541 TI - Intramural lesion of esophagus. PMID- 4297540 TI - Erythropoietin alterations in human genitourinary disease states: correlation with experimental observations. PMID- 4297542 TI - Intensive antibiotic treatment for burns complicated by Pseudomonas infection. PMID- 4297543 TI - [Acquired methemoglobinemia: study of erythrocytic enzymatic patterns]. PMID- 4297544 TI - Toxicity of mercury perchloride when used as an anti-cancer agent in colorectal surgery. PMID- 4297546 TI - Ascorbic acid for treatment of feline rhinotracheitis. PMID- 4297545 TI - Pyrophosphate in the 5' terminal position of a viral ribonucleic acid. AB - A pancreatic ribonuclease digest of carbon-14-labeled Satellite Tobacco Necrosis Virus RNA was fractionated, according to charge, by column chromatography. Individual fractions were dephosphorylated with alkaline phosphomonoesterase and rechromatogramed. The fraction originally containing oligonucleotides with seven negative charges separated into two components corresponding to five and two negative charges, respectively, and therefore must have contained a terminal trinucleotide 5'-pyrophosphate, in addition to the internal hexanucleotides. Other fractions when similarly treated were found to contain only internal oligonucleotides. PMID- 4297548 TI - [Ganglionic action of angiotensin]. PMID- 4297547 TI - [On the histogenesis of cylindroma. An enzyme histochemical study]. PMID- 4297549 TI - [Adrenocorticotropic activity of a synthetic ACTH in humans]. PMID- 4297550 TI - [Pyrophosphatase activity of alkaline phosphatase]. PMID- 4297552 TI - [Influencing of the ACTH-effect by inhibitors of protein synthesis]. PMID- 4297551 TI - [Comparison between a chemical assay and a biological assay of renal renin]. PMID- 4297553 TI - [Cortical influence upon synaptic transmission in the spinal trigeminal nucleus of the cat]. PMID- 4297554 TI - [On the hypertensive reaction to angiotensin II]. PMID- 4297555 TI - [Accumulation of p,p'-DDT and o,p'-DDT in the adrenal cortex and their importance for the metabolism of corticosterone and cortisol]. PMID- 4297556 TI - [Characterization of cells in culture by cytoenzymology]. PMID- 4297557 TI - [Quantitative analysis of biliary acids in the blood by direct densitometry on thin layer chromatography]. PMID- 4297558 TI - [Local immunity in virus infection of the digestive tract]. PMID- 4297559 TI - Extent of release and elimination of noradrenaline at peripheral adrenergic nerve terminals. PMID- 4297560 TI - [On the usability of the so-called phospholipid-demonstration methods in dermatohistology. II. Nonstaining methods]. PMID- 4297561 TI - [A new method of clinical evaluation of the results of drug resistance determination]. PMID- 4297562 TI - Photochemistry of the DNA-acridine dye complexes. PMID- 4297563 TI - [Role of the renin-angiotensin system in homeostasis of the internal environment]. PMID- 4297564 TI - [Coagulases of bacilli of the genus Bordetella]. PMID- 4297565 TI - [Theory of cyclic variations in the occurrence of tumors derived from glia]. PMID- 4297566 TI - Clinical diagnosis of hepatoma. Importance of bruit. PMID- 4297567 TI - [Hypothalamo-hypophysial control of adrenocortical function in the duck]. PMID- 4297568 TI - Factors affecting the toxicity and metabolism of OMPA (octamethylpyrophosphoramide) in rats. PMID- 4297569 TI - Release of renin from dog kidney cortex slices in vitro. PMID- 4297572 TI - Newer and second-line drugs in the treatment of drug-resistant tuberculosis in children. PMID- 4297571 TI - [Metabolism and blood circulation studies in absolute nutrition deficiency]. PMID- 4297573 TI - [Contribution to the knowledge of tumors of the ovary in childhood and puberty]. PMID- 4297574 TI - [On the mechanism of potentiation of catecholamine action following chronic postganglionic sympathetic denervation]. PMID- 4297570 TI - [The physiological role of adipose tissue]. PMID- 4297575 TI - [Preoperative approach to the histologic diagnosis of subtentorial tumors in adults]. PMID- 4297577 TI - [Experimental ulcerogenic effect of various corticosteroids]. PMID- 4297576 TI - [Value of modern technics of photoscintigraphy in the diagnosis of expanding intracranial processes]. PMID- 4297578 TI - [Use os Synacthen as a rapid corticotropin test of adrenal function]. PMID- 4297579 TI - [On the indication for surgery of hypertension in unilateral kidney disease]. PMID- 4297581 TI - [On the significance of the renal excretion of pyrophosphate]. PMID- 4297580 TI - [The treatment of urogenital tuberculosis with current drugs]. PMID- 4297582 TI - Satellitism and related phenomena in plant and animal viruses. PMID- 4297583 TI - A syndrome of retarded development with characteristic appearance. PMID- 4297584 TI - Wilms' tumor and congenital heart disease: report of a case and family. PMID- 4297585 TI - Sex-dependent vascular changes in young, adult, aged, and hypertensive rats. PMID- 4297586 TI - Production of herpes simplex virus by HeLa cells treated with 5-fluoro-2' deoxyuridine. PMID- 4297588 TI - Biological effects of urban air pollution. V. A study of effects of Los Angeles atmosphere on laboratory rodents. PMID- 4297587 TI - Study of chloroquine toxicity and a drug-induced cerebrospinal lipodystrophy in swine. PMID- 4297589 TI - Mixed malignant tumor of the liver in an adult. Case report and review of some features. PMID- 4297590 TI - Generalized cytomegalic inclusion disease of the newborn. Localization of inclusions in the kidney. PMID- 4297591 TI - Marek's disease. II. Propagation of the Connecticut-A isolate in cell cultures. PMID- 4297592 TI - Avian influenza A and paramyxo viruses complicating respiratory disease diagnosis in poultry. PMID- 4297593 TI - Enzymes and intermediates of the pentose phosphate pathway in liver hepatomas. PMID- 4297594 TI - Hexokinase activity and glycolytic capacity of plasma membranes of hepatomas. PMID- 4297595 TI - Brucella abortus in fresh cream and cream products. PMID- 4297596 TI - A continuous spectrophotometric method for the determination of leucine aminopeptidase. PMID- 4297597 TI - Determination of urinary testosterone and epitestosterone in men, women, and children. PMID- 4297598 TI - Production of Arneil-Dekanski factor in vitro by plasma of renal hypertensive rats. PMID- 4297599 TI - Lactic dehydrogenase activity in neuron-free spinal cord tissue obtained by a new method. PMID- 4297600 TI - Clonal analysis of embryonic Chinese hamster cells transformed by Schmidt-Ruppin RSV in vitro. PMID- 4297601 TI - The pineal gland. PMID- 4297602 TI - Protein and RNA metabolism of squid axons (Dosidicus gigas). PMID- 4297603 TI - Evidence for a host cell component in vesicular stomatitis virus. PMID- 4297604 TI - Adsorption, penetration and uncoating of herpes simplex virus. PMID- 4297605 TI - Isolation of a transmissible agent resembling rubella virus from an apparently healthy human embryo lung cell culture. PMID- 4297606 TI - Production of infectious RNA and serum-blocking antigen by poliovirus temperature sensitive mutants. PMID- 4297607 TI - Pepsin digestion of virus particles in canine hepatitis using epon-embedded material. PMID- 4297608 TI - Influence of adrenalectomy and ureteral ligation on the consequences of renal artery constriction in rats. PMID- 4297609 TI - Virus inactivation on clay particles in natural waters. PMID- 4297610 TI - DW 75: a new and potent synthetic corticotrophin analogue. PMID- 4297611 TI - Synovial sarcoma in the scapular region of a 12-year-old child: a case report. PMID- 4297612 TI - Enanthems associated with uncommon viral syndromes. PMID- 4297613 TI - Triple antibiotic tulle. PMID- 4297614 TI - Comparison of two lots of immune serum globulin for prophylaxis of infectious hepatitis. PMID- 4297615 TI - Monkey pox. I. Clinical, virologic and immunologic studies. PMID- 4297616 TI - Effects of angiotensin, norepinephrine and renal artery constriction on erythropoietin production. PMID- 4297617 TI - Extra-renal and renal control of erythropoietin production. PMID- 4297618 TI - Malignant lymphoproliferative diseases: interactions between immunological abnormalities and oncogenic viruses. PMID- 4297619 TI - Growth and physiological development during adolescence. PMID- 4297620 TI - Histochemical studies on the mamillary body of the rabbit. PMID- 4297621 TI - Comparison of lesions in acute and chronic African swine fever. PMID- 4297622 TI - The antigenic relationship of bovine and human strains of parainfluenza-3 virus demonstrated by immunodiffusion. PMID- 4297623 TI - Studies on the pathogenesis of infectious bovine rhinotracheitis following aerosol exposure. PMID- 4297624 TI - Aflatoxin risks and control measures. PMID- 4297625 TI - Incorporation of radioactivity from methionine-methyl-14C into phospholipids by Nocardia polychromogenes. PMID- 4297626 TI - Mode of action and base specificity of a nuclease from the silkworm. PMID- 4297627 TI - Comparative studies on the glucose oxidases of Aspergillus niger and penicillium amagasakiense. PMID- 4297628 TI - Adenosine triphosphate and pyrophosphate dependent phenylalanine racemase of Bacillus brevis Nagano. PMID- 4297629 TI - Studies on leukocyte metabolism. I. PMID- 4297631 TI - Cancer of the urogenital tract: Wilms' tumor and neuroblastoma. Neuroblastoma. PMID- 4297630 TI - Factors modifying host resistance to viral infection. 3. Effect of whole body x irradiation on experimental encephalomyocarditis virus infection in mice. AB - The resistance of mice to encephalomyocarditis (EMC) virus was markedly decreased by prior exposure to whole body X-irradiation. In contrast to non-irradiated controls, the course of EMC virus infection in X-irradiated animals was characterized by (a) an enhanced mortality, (b) shortening of the incubation period, (c) higher levels of virus in the blood during the viremic phase and persistence of the viremia until death, (d) failure to develop detectable serum levels of neutralizing antibody, and (e) the earlier appearance and higher levels of virus in brain and heart tissue. The level of interferon in the serum during the course of infection was similar in both groups. The administration of relatively small quantities of anti-EMC virus neutralizing antibody to X irradiated mice during the early phases of the infection with EMC virus restored their resistance to levels comparable to nonirradiated animals. An alteration of local organ defense mechanisms in the central nervous system could not be demonstrated. It is proposed that (a) the inability of the X-irradiated animal to elaborate specific neutralizing antibody was a critical determinant in their failure to clear the viremia, (b) this increase in the level and duration of the viremic phase resulted in the exposure of target organs to a greater inoculum of virus, and (c) the enhanced mortality observed in irradiated mice reflected this greater target organ involvement. The experimental model presented, therefore, suggests that the immunologic response is a critical determinant of host resistance during this primary systemic virus infection. PMID- 4297632 TI - Cancer of the urogenital tract: Wilms' tumor and neuroblastoma. Comment. Cure and the growth rate of childhood tumors. PMID- 4297633 TI - Association of recurrent herpes simplex with neuralgia. PMID- 4297634 TI - Interrelationship between angiotensin and catecholamines. PMID- 4297635 TI - Passive cellular immunity in tumor-bearing mice. PMID- 4297636 TI - Comparative studies on the structure and properties of two selected strains of Japanese encephalitis virus. PMID- 4297637 TI - Chainin: a new methylpentaene antibiotic from a species of Chainia. PMID- 4297638 TI - [The radiation effect on the DNA synthesis in tumor cells]. PMID- 4297639 TI - Gliomas of the quadrigeminal plate and eye movements. PMID- 4297640 TI - The future of vaccines against viral diseases. PMID- 4297642 TI - Paget's disease of perianal skin. PMID- 4297643 TI - Autoimmunity in oral diseases, with special reference to recurrent oral ulceration. PMID- 4297641 TI - Chemical mediators in the central nervous system. PMID- 4297644 TI - Cyanovinyl phosphate: a prebiological phosphorylating agent? AB - Cyanovinyl phosphate may be prepared by the addition reaction of phosphate to cyanoacetylene. Kinetic studies have established that cyanovinyl phosphate undergoes a slow pseudo-first-order hydrolysis in aqueous solution. Cyanovinyl phosphate converts uridine to uridine monophosphate and phosphate to pyrophosphate. PMID- 4297645 TI - Cytological studies on host-parasite relations in experimental leprosy of mice. PMID- 4297646 TI - Plasma angiotensinase activity in rabbits with experimental renal hypertension. PMID- 4297647 TI - Influence of reticuloendothelial function on the growth of transplantable rat ascites hepatoma (AH-130). PMID- 4297648 TI - Structure of simian virus 40. 3. Alkaline degradation of the virus particle. PMID- 4297649 TI - Oxidation of methylmalonate semialdehyde to propionyl coenzyme A in Pseudomonas aeruginosa grown on valine. PMID- 4297650 TI - Pleomorphic adenoma of the palate. A case report. PMID- 4297651 TI - The treatment of mixed parotid tumours. A report of 183 cases. PMID- 4297652 TI - [6d. Renovascular hypertension. Pathogenetic principles and clinical picture]. PMID- 4297654 TI - [Application of electron spin resonance in the study of biology]. PMID- 4297653 TI - Current concepts of burn injury. 3. PMID- 4297655 TI - Maturity as a biological concept. PMID- 4297656 TI - [Neoplasms of the salivary glands]. PMID- 4297657 TI - Electrical pacing of the heart with observations on the single and paired electrical stimuli during acute reversible experimental heart failure in the anaesthetized dog. PMID- 4297659 TI - [Special institutions insure care]. PMID- 4297658 TI - The cytochrome oxidase activity of pneumoconiotic tissue as parameter of cellular hypoxia. PMID- 4297660 TI - [Biological characteristics of tumor cells and their possibilities for microbiological diagnosis]. PMID- 4297661 TI - [On some results of the laboratory diagnosis of bone sarcoma]. PMID- 4297662 TI - [Neuroblastoma and kidney sarcoma in childhood]. PMID- 4297663 TI - [Clinical and therapeutic problems in synovial sarcoma]. PMID- 4297664 TI - [On the histochemistry of venous autotransplants]. PMID- 4297665 TI - A case of orf (ecthyma contagiosum; contagious pustular dermatitis) contracted by a human from a wild Alaskan mountain goat. PMID- 4297666 TI - Varicella pneumonia in pregnancy. PMID- 4297667 TI - [Use of acetoxan and prodigiozan in combination with antibiotics in mixed purulent infection]. PMID- 4297668 TI - [Specificity in fatty acid composition of phospholipids of mitochondrial membranes]. PMID- 4297669 TI - Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice. PMID- 4297671 TI - Histometrical estimation of the corticotrophin secreting cells in the adenohypophysis of bilaterally adrenalectomized rats. PMID- 4297670 TI - Cytochemical studies on the second gradient axis of fertilized oyster eggs. IV. On the activity of ATPase and reduced NAD dehydrogenase. PMID- 4297672 TI - [Extrahypophyseal corticotropic tumors]. PMID- 4297673 TI - [Electron microscopy study of an androgen-forming adrenocortical adenoma]. PMID- 4297674 TI - Studies on methionyl transfer RNA synthetase. 1. Purification and some properties of methionyl transfer RNA synthetase from Escherichia coli K-12. PMID- 4297675 TI - [Isolation of poliovirus in poliomyelitic patients vaccinated with Sabin vaccine]. PMID- 4297676 TI - Partial antagonism of experimental botulinal intoxication. PMID- 4297677 TI - Neuroblastoma: a viral etiology? PMID- 4297678 TI - Biotransformation studies on 1-chloro-2,3-propanediol dinitrate. PMID- 4297679 TI - Development and evaluation of a sampling device for the analysis of pharmaceutical aerosols. PMID- 4297680 TI - Effect of mescaline on nicotinamide adenine dinucleotide synthesis in the central nervous system. PMID- 4297681 TI - Treatment of diseases of the testes affecting growth and development. PMID- 4297682 TI - [Demonstration of 3-hydroxyanthranilic acid oxygenase in Saccharomyces cerevisiae]. PMID- 4297683 TI - Genetic aspects of tumors of the nervous system. II. PMID- 4297684 TI - Aldosterone deficiency in chronic renal failure. PMID- 4297685 TI - [On the diagnosis of gliomas]. PMID- 4297686 TI - Daunomycin pharmacological activity at the cellular level. PMID- 4297687 TI - [Trial of rubidomycin in 11 cases of solid tumors in children]. PMID- 4297688 TI - [Considerations on cancer of the male breast based on 9 cases]. PMID- 4297689 TI - Relation of pock size on chorioallantoic membrane to antigenic type of herpesvirus hominis. PMID- 4297690 TI - Studies of adenovirus type 3 infection treated with methisazone and trifluorothymidine. PMID- 4297691 TI - Human cytomegalovirus, observations of intracellular lesion development as revealed by phase contrast, time-lapse cinematography. PMID- 4297692 TI - Hemagglutinin of rabies and some other bullet-shaped viruses. PMID- 4297693 TI - The influence of serotonin on oxidative metabolism of brain mitochondria. PMID- 4297694 TI - Experimental infections of chimpanzees with human rhinovirus types 14 and 43. PMID- 4297695 TI - Histochemical investigation of hepatic adenosine triphosphatase and glucose-6 phosphatase activity in hemorrhagic shock. PMID- 4297696 TI - Yellow fever vaccine. I. Development of a vaccine seed free from contaminating avian leukosis viruses. PMID- 4297697 TI - Histamine hypersensitivity of mice induced by 5'-AMP. PMID- 4297698 TI - Pyelonephritis in the mouse. 3. Therapeutic experiments. PMID- 4297699 TI - Reovirus type 2: production of and sensitivity to interferon in human amnion cells. PMID- 4297700 TI - Induction of the interferon system by various inducers. PMID- 4297701 TI - A variant of parainfluenza type 2 virus. PMID- 4297702 TI - Two cases of metastasizing scirrhous gastric carcinoma simulating idiopathic retroperitoneal fibrosis. PMID- 4297703 TI - [The technical artifice of Lamy and Bricot applied to the Soupault-Bucaille reconversion operation. (Apropos of 2 cases)]. PMID- 4297704 TI - [Studies on the development of giant cells in mouse macrophage cultures infected with mouse hepatitis virus (MHV-3)]. PMID- 4297705 TI - [Antibacterial therapy in the newborn infant]. PMID- 4297706 TI - [On the clinical course, etiology and therapy of familial forms of atrophic myotonias]. PMID- 4297707 TI - [Determination of aldosterone in paroxysmal myoplegia]. PMID- 4297708 TI - The effect of reserpine on transmission in the spinal cord. PMID- 4297709 TI - Is the tonic decerebrate inhibition of reflex paths mediated by monoaminergic pathways? PMID- 4297710 TI - Differences in the subcellular localization of choline, acetylcholine and atropine taken up by mouse brain slices in vitro. PMID- 4297711 TI - [Virilirence tumors of the ovaries]. PMID- 4297712 TI - [Glucocorticoids and glucose metabolism. I. Comparative studies on the glucose increasing effect of adrenocorticotropic hormones and newer glucocorticoids]. PMID- 4297713 TI - New methods of production and partial purification of an antiviral substance from Penicillium cyaneo-fulvum. PMID- 4297714 TI - [Influence of adrenocorticotropic hormone on the nonesterified fatty acid composition of normal human plasma]. PMID- 4297715 TI - Screening for disorders of amino acid metabolism by thin-layer high voltage electrophoresis. PMID- 4297716 TI - Beta-alaninuria following human renal allotransplantation. PMID- 4297717 TI - Segregation of a nonhemadsorbing African swine fever virus in tissue culture. PMID- 4297718 TI - High mortality in a Florida swine herd infected with the encephalomyocarditis virus. An accompanying epizootiologic survey. PMID- 4297719 TI - [Tumor immunology]. PMID- 4297720 TI - [Induction of the "stripping enzyme" in different viruses of the smallpox vaccinia group]. PMID- 4297721 TI - [Effect of cortisone on enzyme induction in isolated liver]. PMID- 4297723 TI - Peripheral neuropathies. PMID- 4297722 TI - Histochemical mapping of succinic dehydrogenase and cytochrome oxidase in the diencephalon and basal telencephalic centers of the brain of squirrel monkey (Saimiri sciureus). PMID- 4297724 TI - Fatty acid composition of serum cholesteryl ester fractions isolated by thin layer chromatography. PMID- 4297725 TI - [Reiter's syndrome]. PMID- 4297726 TI - Hereditary brachial and cranial neuritis genetically linked with ocular hypotelorism and syndactyly. PMID- 4297728 TI - Effects of nervous system lesions on phantom experience in amputees. PMID- 4297727 TI - Steroid therapy of non-infantile (childhood) myoclonic epilepsy. PMID- 4297729 TI - [On 100 cases of pleomorphic adenoma of the parotid gland]. PMID- 4297730 TI - [On lymph-sialo-adenography]. PMID- 4297731 TI - [Unusual benign tumors of the trachea. Leiomyoma, intratracheal struma]. PMID- 4297732 TI - ATPase activity of membrane ghosts obtained from mitochondria. PMID- 4297733 TI - Induction of mannitol dissimilation in Mycobacterium phlei. PMID- 4297734 TI - [Cytomegalovirus infection--problems in experimental technics and clinical evaluation]. PMID- 4297736 TI - Sorbents and catalysts for respirator cartridges and gas mask canisters. PMID- 4297735 TI - Metal and mineral concentrations in lungs of bituminous coal miners. PMID- 4297737 TI - Colorimetric personal dosimeter for hydrazine fuel handlers. PMID- 4297738 TI - Laser destruction of experimental tumors: state of the art and protection of personnel. PMID- 4297740 TI - [Electron microscopic findings on the ultrastructure and viruses of the vesicles of varicella]. PMID- 4297739 TI - [Observations on the physiopathology of the regulation of aldosterone in the course Schwartz-Bartter Syndrome]. PMID- 4297741 TI - Sensitivity of Klebsiella bacilli to antibiotics. PMID- 4297742 TI - Multiple antibiotic resistance of Shigella flexneri 6. PMID- 4297743 TI - Resistance of Shigella sonnei to antibiotics. PMID- 4297744 TI - [Detection and determination of cyanide in biological material]. PMID- 4297745 TI - The orf viruses in man and animals. PMID- 4297746 TI - Immunochemical analysis of Mycoplasma pneumoniae. 2. Properties of chloroform methanol extract from M. pneumoniae. PMID- 4297747 TI - [Ultrastructural findings in the regional lymph nodes after intralymphatic radiotherapy in cases of carcinoma of the bladder]. PMID- 4297748 TI - [The hereditary fixation of the dentition. An attempt at a molecular-genetic interpretation]. PMID- 4297749 TI - Effect of antibiotics on vascular permeability. PMID- 4297750 TI - Influence of antibiotics on pregnancy. Cumulative study on trichomycin administered patients. PMID- 4297751 TI - Ultrastructural and cytochemical observations on B-16 and Harding-Passey mouse melanomas. The origin of premelanosomes and compound melanosomes. PMID- 4297752 TI - [Resuscitation of the burned patient]. PMID- 4297753 TI - [Collins' "risk period" in malignant tumors of childhood]. PMID- 4297754 TI - [Chemotherapy of herpes infection with new 5-alkyluracildeoxyribosides]. PMID- 4297755 TI - [Qualitatively and quantitatively different effects of alpha-methyldopa treatment on cats according to a dosage scheme]. PMID- 4297756 TI - [Influence of diuretics on 3',5'-AMP-phosphodiesterase]. PMID- 4297758 TI - [Effect of an negative potassium balance on hormonal and enzymatic regulation of carbohydrate metabolism]. PMID- 4297757 TI - [Dependency of glycogen synthetic and degradative enzymatic reactions upon insulin secretion]. PMID- 4297759 TI - Drugs affecting transmitter release from motor nerve terminals. PMID- 4297760 TI - I. Organisation of spinal units. History of the National Spinal Injuries Centre, Stoke Mandeville Hospital, Aylesbury. PMID- 4297761 TI - The organisation of a Spinal Injuries Unit at Royal Perth Hospital, Perth, Western Australia. PMID- 4297762 TI - [Immunization against "market pneumonia" of cattle]. PMID- 4297763 TI - [Renal angiography in childhood]. PMID- 4297764 TI - [The relationships between vaccinia on hands of milkers, udder smallpox, papulous stomatitis and contagious ecthyma]. PMID- 4297765 TI - [Comparative studies on the carbohydrate metabolism of erythrocytes in healthy rats and of reticulocytes in rats with phenylhydrazinemia]. PMID- 4297766 TI - [Radiological diagnosis of glomus tumors in the ear region]. PMID- 4297767 TI - [Histochemical findings in a mixed tumor of the external auditory meatus]. PMID- 4297768 TI - [On neurosecretory innervation of the adenohypophysis in teleost fishes, especially in the Hippocampus cuda and Tinca tinca]. PMID- 4297769 TI - Peripheral neuropathy in chronic disease of the respiratory tract. PMID- 4297770 TI - Postappendectomy fistula due to residual fecalith. PMID- 4297771 TI - Hepatic effects following abdominal irradiation in children: detection by Au198 scan and confirmation by histologic examination. PMID- 4297772 TI - N6-(Delta 2-isopentenyl)adenosine: biosynthesis in vitro by an enzyme extract from yeast and rat liver. PMID- 4297773 TI - Community psychiatry. PMID- 4297774 TI - Involuntary movements in multiple sclerosis. PMID- 4297775 TI - Cytomegalic inclusion-body disease associated with acquired autoimmune haemolytic anaemia. PMID- 4297776 TI - The effect of propranolol on circulatory adaptations to volume and pressure loads. PMID- 4297777 TI - Fragility of liver mitochondria in ethanol-fed rats. PMID- 4297778 TI - Case records of the Angell Memorial Animal Hospital. PMID- 4297779 TI - Identification and cobamide coenzyme-dependent formation of 3,5-diaminohexanoic acid, an intermediate in lysine fermentation. PMID- 4297780 TI - Influence of added pyruvate on brain metabolism. A Pasteur-like effect, reversible by electrical stimulation. PMID- 4297781 TI - Properties of the nicotinamide adenine dinucleotide-binding sites of L-alpha glycerophosphate dehydrogenase. PMID- 4297782 TI - Allosteric interactions of a regulatory nicotinamide adenine dinucleotide specific glutamate dehydrogenase from Blastocladiella. A molecular model for the enzyme. PMID- 4297783 TI - A soluble cytochrome P-450 functional in methylene hydroxylation. PMID- 4297784 TI - Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. PMID- 4297785 TI - The biogenesis of mitochondria. 3. The lipid composition of aerobically and anaerobically grown Saccharomyces cerevisiae as related to the membrane systems of the cells. AB - The growth conditions known to influence the occurrence of mitochondrial profiles and other cell membrane systems in anaerobic cells of S. cerevisiae have been examined, and the effect of the several growth media on the lipid composition of the organism has been determined. The anaerobic cell type containing neither detectable mitochondrial profiles nor the large cell vacuole may be obtained by the culture of the organism on growth-limiting levels of the lipids, ergosterol, and unsaturated fatty acids. Under these conditions, the organism has a high content of short-chain saturated fatty acids (10:0, 12:0), phosphatidyl choline, and squalene, compared with aerobically grown cells, and it is especially low in phosphatidyl ethanolamine and the glycerol phosphatides (phosphatidyl glycerol + cardiolipin). The high levels of unsaturated fatty acids normally found in the phospholipids of the aerobic cells are largely replaced by the short-chain saturated acids, even though the phospholipid fraction contains virtually all of the small amounts of unsaturated fatty acid present in the anaerobic cells. Such anaerobic cells may contain as little as 0.12 mg of ergosterol per g dry weight of cells while the aerobic cells contain about 6 mg of ergosterol per g dry weight. Anaerobic cell types containing mitochondrial profiles can be obtained by the culture of the organism in the presence of excess quantities of ergosterol and unsaturated fatty acids. Such cells have increased levels of total phospholipid, ergosterol, and unsaturated fatty acids, although these compounds do not reach the levels found in aerobic cells. The level of ergosterol in anaerobic cells is markedly influenced by the nature of the carbohydrate in the medium; those cells grown on galactose media supplemented with ergosterol and unsaturated fatty acids have well defined mitochondrial profiles and an ergosterol content (2 mg per g dry weight of cells) three times that of equivalent glucose-grown cells which have poorly defined organelle profiles. Anaerobic cells which are low in ergosterol synthesize increased amounts of squalene. PMID- 4297786 TI - The large-scale separation of peroxisomes, mitochondria, and lysosomes from the livers of rats injected with triton WR-1339. Improved isolation procedures, automated analysis, biochemical and morphological properties of fractions. AB - Improved, largely automated methods are described for the purification and analysis o peroxisomes, lysosomes, and mitochondria from the livers of rats injected with Triton WR-1339. With these new methods, it has become possible to obtain, in less than 6 hr and with reliable reproducibility, mitochondria practically free of contaminants, as well as the rarer cytoplasmic particles in amounts (about 100 mg of protein) and in a state of purity (95%) that make them suitable for detailed biochemical studies. The results obtained so far on these preparations have made more conclusive and precise previous estimates of the biochemical and morphological properties of the three groups of cytoplasmic particles. In addition, peroxisomes were found to contain essentially all the L alpha-hydroxy acid oxidase of the liver, as well as a small, but significant fraction of its NADP-linked isocitrate dehydrogenase activity. Another small fraction of the latter enzyme is present in the mitochondria, the remainder being associated with the cell sap. The mitochondrial localization of the metabolically active cytoplasmic DNA could be verified. The relative content of the fractions in mitochondria, whole peroxisomes, peroxisome cores, lysosomes, and endoplasmic reticulum was estimated independently by direct measurements on electron micrographs, and by linear programming (based on the assumption that the particles are biochemically homogeneous) of the results of enzyme assays. The two types of estimates agreed very well, except for one fraction in which low cytochrome oxidase activity was associated with mitochondrial damage. PMID- 4297787 TI - The occurrence in yeast of cytoplasmic granules which resemble microbodies. PMID- 4297788 TI - The detection and estimation of pentachlorophenol in natural latex by thin-layer chromatography. PMID- 4297789 TI - Thin-layer chromatography of vitamin D and related sterols. PMID- 4297790 TI - Simultaneous Graves' disease and Cushing's syndrome with unusually low levels of plasma cortisol. PMID- 4297791 TI - Endocrine function in thalassemia major. PMID- 4297792 TI - Enterohepatic metabolism of estriol-3-sulfate-16-glucosiduronate in women. PMID- 4297793 TI - Bilateral carcinoma of the breast in a patient with Klinefelter's syndrome. PMID- 4297795 TI - The development of bovine syndactylism. PMID- 4297794 TI - Failure of placental microsomes to aromatize testosterone sulfate. PMID- 4297796 TI - A comparative in vivo and in vitro study of normal peripheral nerve and nerve tumors. PMID- 4297797 TI - Uptake of peroxidase and other proteins by murine brain tumors. PMID- 4297798 TI - Apparent nucleoside phosphatase activity in the neurofibrillary tangles of Alzheimer's disease. PMID- 4297800 TI - Ganglionic actions of alpha,alpha'-bis-(dimethylammoniumacetaldehyde diethylacetal)-p,p'-diacetylbiphenyl dibromide (DMAE). PMID- 4297799 TI - Thermal alteration in receptor activity of the rat fundal strip. PMID- 4297801 TI - The antiarrhythmic properties of ICI 46037, a quaternary analog of propranolol. PMID- 4297802 TI - Formation of a "false" adrenergic transmitter in cats pretreated with 4-methyoxy 3,5-dihydroxyphenylalanine and its effects on postganglionic sympathetic transmission. PMID- 4297803 TI - Angiotensin, cocaine and desipramine: comparison of effects on blood pressure responses to norepinephrine, tyramine and phenylephrine in the pithed rat. PMID- 4297804 TI - The actions of angiotensin II on canine myocardial and plasma catecholamines. PMID- 4297805 TI - The herpes simplex virus and the nervous system. Review of the literature. PMID- 4297806 TI - Tissue hormones: angiotensin, bradykinin and the regulation of regional blood flows. PMID- 4297807 TI - Hypoglycemia: tolbutamide and leucine tests in insulinoma. PMID- 4297808 TI - Disturbances of pituitary function in central nervous system disease. PMID- 4297809 TI - Effects of local anaesthetic on the state of water in frog nerves. PMID- 4297810 TI - Activation of isolated lysosomes by poliovirus-infected cell extracts. PMID- 4297811 TI - Biological activity of synthetic 1-39 human corticotropin. PMID- 4297812 TI - New enzymatic route for the inactivation of angiotensin. PMID- 4297813 TI - RNA synthesis in yeast mitochondria: a derepressible activity. PMID- 4297814 TI - Trapping of free radicals formed by gamma-irradiation of organic compounds. PMID- 4297815 TI - Rat tissue DPNH-cytochrome c reductase activity in altered thyroid states. PMID- 4297816 TI - Hemorrhagic diathesis in laboratory rodents. PMID- 4297817 TI - Postnatal changes in the pituitary-adrenal axis of the rat. PMID- 4297818 TI - Effect of metals upon the conversion of adenosine triphosphate to adenosine 3',5'monophosphate in lipocytes. PMID- 4297819 TI - Purification of a horse placental inhibitor to hemagglutination by H-1 or HB viruses. PMID- 4297820 TI - Intensive nursing and lactational performance during extended lactation. PMID- 4297821 TI - Plaque formation by rhinoviruses. PMID- 4297822 TI - The effect of dimethyl sulfoxide (DMSO) on cellular systems. PMID- 4297823 TI - Fractionation of an esterase from calf spleen implicated in the detoxification of bacterial endotoxin. PMID- 4297824 TI - The management of ulcerative colitis. PMID- 4297825 TI - The ultracentrifugal patterns and chemical composition of ribosomal RNA from liver and hepatoma. PMID- 4297826 TI - [Presence of some hydrolases and oxidoreductases in Leydig cells in the testes of pubescent rats]. PMID- 4297827 TI - Histochemical studies on the cerebellum of squirrel monkey (Saimiri sciureus). PMID- 4297828 TI - Topochemistry of hydrolytic enzymes in relation to Golgi apparatus in transplanted spontaneous mammary cancer of C3H mice. PMID- 4297829 TI - Functional analysis of subcortical interactions between thalamic somatosensory relay-nuclei. PMID- 4297830 TI - [Strains of "super-dependent" poliovirus which require cytotoxic doses of guanidine for development]. PMID- 4297831 TI - [Effect of pulmonary lipoproteins on the cytotoxic activity of silica. I. Inhibition of the hemolytic effect of a submicronic amorphous silica by bovine pulmonary thromboplastic lipoprotein]. PMID- 4297832 TI - [Effect of pulmonary lipoproteins on the cytotoxic activity of silica. II. Inhibition of the hemolytic effect of a submicronic amorphous silica by surface active lipoprotein from rat lung]. PMID- 4297833 TI - [Observations on the influence of hyperbaric oxygenation on experimental mouse hepatitis caused by MHV-3 virus]. PMID- 4297834 TI - [Preliminary observations on the influence of acute CCl-4 poisoning on experimental mouse hepatitis caused by MHV-3 virus]. PMID- 4297835 TI - [Adrenal hirsutism (3-beta-hydroxysteroid dehydrogenase deficiency). Studies using a chromatographic separation of the urinary 17-ketosteroid fraction. 2. Dehydroepiandrosterone-forming adrenal hyperplasia and constitutional hirsutism]. PMID- 4297837 TI - [Demonstration and reaction of the rat liver following intraportal application of lipiodol ultra fluid]. PMID- 4297836 TI - [On the histophysiology of the rat adrenal cortex following thioacetamide (TAA) injection and ACTH stimulation]. PMID- 4297838 TI - [Lymphographic demonstration of chyluria]. PMID- 4297840 TI - [The renin activity in renal artery stenosis in the peripheral blood and in kidney venous blood in comparison with other kidney function tests]. PMID- 4297839 TI - [The treatment of choriocarcinoma and malignant testicular neoplasms]. PMID- 4297841 TI - The virus causes of coughs and colds. PMID- 4297842 TI - [Clinical aspects of virus diseases]. PMID- 4297843 TI - [On the regulation of renin secretion through angiotensin]. PMID- 4297844 TI - [The effect of lithium chloride on the blood pressure actions of renin, angiotensin and noradrenaline in rats]. PMID- 4297845 TI - [Urinary pyrophosphate level in lithiasis. Results of clinical studies on orthophosphate prevention of recurrent lithiasis]. PMID- 4297846 TI - [Brain tumors in the small child]. PMID- 4297847 TI - The interaction of different phospholipids on the blood clotting mechanism. PMID- 4297848 TI - [Clinical electrodiagnosis of the peripheral nervous system with special reference to stimulation-current diagnosis]. PMID- 4297849 TI - [Animal experimental studies on the behavior of potassium and sodium in the blood and heart muscle during histamine shock and orthostatic collapse]. PMID- 4297850 TI - [On the clinical aspects of urachus carcinoma]. PMID- 4297851 TI - Human chorionic gonadotrophin excretion in men and women with invasive trophoblast assayed by an immunological and a biological method. PMID- 4297852 TI - Hypothalamo-pituitary-adrenal function in hypercorticosteroid states. PMID- 4297853 TI - Ovarian activities of pyridine nucleotide dependent dehydrogenases in the rat during pregnancy and lactation. PMID- 4297854 TI - Some aspects of transmission at the nerve-smooth muscle junction in the longitudinal muscle of the guinea pig ileum. PMID- 4297856 TI - Electron microscopy of bovine papilloma and deer fibroma viruses. PMID- 4297857 TI - Experimental production of canine tracheobronchitis (kennel cough) with canine herpesvirus isolated from naturally infected dogs. PMID- 4297858 TI - Charcoal agglutination test for the detection of antibodies to infectious canine hepatitis virus: comparison of charcoal agglutination, complement-fixation, and serum-neutralization tests. PMID- 4297859 TI - Granular cell myoblastoma of the canine tongue: case reports. PMID- 4297860 TI - Inhibition of hepatic gluconeogenesis in guinea pig by phenformin. PMID- 4297861 TI - In vitro effects of phenformin hydrochloride: observations using isolated fat cells. PMID- 4297862 TI - [Cytochemical study of the action of levomycetin on tissue culture cells]. PMID- 4297863 TI - [Study of toxicity of polymyxin M and its action on endotoxin of Salm. pullorum]. PMID- 4297864 TI - [On the action of antibiotics on the body regulatory system]. PMID- 4297865 TI - [Polarimetric method of determination of ristomycin A in eluates]. PMID- 4297866 TI - Oxidation-reduction components of a reduced diphosphopyridine nucleotide dehydrogenase. PMID- 4297867 TI - Action of spleen phosphodiesterase uponsoluble ribonucleic acid. PMID- 4297868 TI - Comparison of amino acid polymerization factors isolated from rat liver and rabbit reticulocytes. PMID- 4297869 TI - Deproteinization of cell extract with silicic acid. PMID- 4297870 TI - Involvement of transfer ribonucleic acid in early reactions of polyphenylalanine synthesis. PMID- 4297871 TI - [Histochemical study of iron and cytochrome oxidase in the myocardium in experimental myocarditis]. PMID- 4297872 TI - Natural history of herpetic infection. PMID- 4297873 TI - Pleomorphic adenoma in the neck of a child. PMID- 4297874 TI - Induction of thymidine-3H incorporation in multinucleated myotubes by Rous sarcoma virus. PMID- 4297875 TI - An X-band electron spin resonance spectrometer with a ruby maser preamplifier. PMID- 4297877 TI - [Studies on the character of heterogenous serological reactions in humans in natural infection with some myxoviruses]. PMID- 4297876 TI - The impairment of glucogenesis by gram negative infection. PMID- 4297878 TI - [Conditions of formation of anatoxins of Clostridium perfringens, Cl. Oedematiens and Cl. septicum from toxins obtained in casein media]. PMID- 4297879 TI - Phosphorus depletion in man. PMID- 4297880 TI - The oncogenicity of human adenoviruses in hamsters. PMID- 4297881 TI - Long term maintenance of cell cultures under agar overlay and development of herpes T plaques. PMID- 4297882 TI - The action of cortisone on the metabolism of the normal, intoxicated, or vitamin B12 protected liver cell. PMID- 4297883 TI - Amoebic meningoencephalitis. PMID- 4297884 TI - Virological examination of children with acute exanthematous disease. PMID- 4297885 TI - Saturated fatty acids in poliovirus host cell interaction. I. Stimulation and inhibition of virion uptake. PMID- 4297886 TI - Saturated fatty acids in poliovirus host cell interaction. II. Model experimental on stimulation of phagocytosis. PMID- 4297887 TI - Studies of etiology of laryngeal papilloma and an autogenous laryngeal papilloma vaccine. PMID- 4297888 TI - Protective effect of sucrose and mannitol against vasoconstriction induced by angiotensin II in the kidney. PMID- 4297889 TI - Correlation between renal renin content and number of juxtaglomerular granular cells. PMID- 4297890 TI - [Comments on the epithelial and connective-tissue interaction in cutaneous tumors: apropos of epithelial proliferation in histiocytofibromas]. PMID- 4297891 TI - [Subacute sclerosing leukoencephalitis with fulminant course]. PMID- 4297892 TI - Control of erythritol dehydrogenase in Schizophyllum commune. PMID- 4297894 TI - Variation of ESR signal amplitude with duration of tumor growth. PMID- 4297893 TI - Nitrate reduction in Aerobacter aerogenes. I. Isolation and properties of mutant strains blocked in nitrate assimilation and resistant against chlorate. PMID- 4297895 TI - [Therapy of regional enteritis]. PMID- 4297896 TI - Electron spin resonance study on the interaction between chemical carcinogens and tissue components. II. Free radicals produced by stirring aromatic hydrocarbons with tissue components such as skin homogenates or proteins. PMID- 4297898 TI - Methods for identifying neuroplasmic components conveyed to muscle cells via the axons. PMID- 4297897 TI - DNA content of rat ascites hepatoma cells with hyppo- and hyper-diploid number of chromosomes. PMID- 4297899 TI - Degradation of yeast ribonucleic acid by polynucleotide phosphorylase from Azotobacter agilis (vinelandii). II. Effect of terminal phosphate of ribonucleic acid and effect of ribonucleoside 5'-diphosphate. PMID- 4297900 TI - Studies on cytochrome oxidase of yeast. I. Purification and enzymatic activity of cytochrome oxidase from saccharomyces oviformis M2. PMID- 4297901 TI - Electron spin resonance studies of free radicals in gamma-irradiated amino acid crystals: alpha-amino isobutyric acid and L-lysine-HCl-2H2O. PMID- 4297902 TI - Angiotensinase activity using human crude angiotensin. PMID- 4297903 TI - Acid angiotensinase, renin, and acid adenosine triphosphatase in rat kidney lysosomes. PMID- 4297904 TI - The role of mammals as primary and supplementary hosts. PMID- 4297905 TI - Japanese encephalitis vaccine including a preliminary report on dengue fever and Chikungunya vaccines. PMID- 4297906 TI - Vector control in Asia. PMID- 4297907 TI - Epidemics of mosquito-borne virus diseases in the Pacific area, exclusive of dengue and Chikungunya viruses with emphasis on the past five years. PMID- 4297908 TI - A phase cinematography study on morphological changes of FL-line cells following the infection of poliovirus. PMID- 4297909 TI - Studies on the protection test of pertussis vaccine. Immunization period and protectivity. 3. Influence of heat and formation on the vaccine preparation. PMID- 4297910 TI - [Remote sequels of hypsarhythmic encephalopathy]. PMID- 4297911 TI - [Introlymphatic radiotherapy in the treatment of lymph node metastases of carcinoma of the bladder]. PMID- 4297912 TI - [Muscle transplants in definitive post-traumatic paralysis of the peripheral nerves]. PMID- 4297913 TI - Electron paramagnetic resonance of chlorophyll-water aggregates. PMID- 4297914 TI - Action of hydrogenated ergot alkaloids upon transmission to sweat glands in the cat. PMID- 4297915 TI - Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability. PMID- 4297916 TI - The activation of amino acids for biosynthesis of gramicidin S. PMID- 4297917 TI - [Virus encephalitis]. PMID- 4297918 TI - [Virus rhinitis]. PMID- 4297919 TI - [Cytomegaly]. PMID- 4297921 TI - [Experience with reducing temporary work incapacity in diseases of the peripheral nervous system]. PMID- 4297920 TI - [Glucocorticoid function of the adrenal cortex in patients with lupus erythematosus]. PMID- 4297922 TI - Realistic utilization: levels of preparation. PMID- 4297923 TI - The development of the psychoanalytic concept of depression. PMID- 4297924 TI - A behavior rating scale for assessing nursing care requirements of psychiatric patients. PMID- 4297925 TI - A parent speaks. PMID- 4297927 TI - The organization of psychiatric services in the USSR and the role of the nurse. PMID- 4297928 TI - Psychiatric drugs and trends. The alarming comeback of gonorrhea. PMID- 4297926 TI - The penthouse--a discharge oriented unit. PMID- 4297929 TI - Geriatrics. PMID- 4297930 TI - [Non-familial ulcero-mutilating acropathia of the lower extremities]. PMID- 4297931 TI - [The role of cytomegalic disease in neonatal pathology]. PMID- 4297932 TI - [Attempts at the experimental selection of a myelotropic strain of the MHV-3 virus]. PMID- 4297933 TI - Porcine polioencephalomyelitides. PMID- 4297934 TI - Factitious genital sclerogranuloma. PMID- 4297935 TI - Topical spray of antibiotics in simulated combat wounds. IV. Dose factor. PMID- 4297936 TI - [Relation between digitalis therapy and oxidative metabolism of the myocardium (preliminary note)]. PMID- 4297937 TI - The mechanism of glucose 6-phosphate-D-myo-inositol 1-phosphate cyclase of rat testis. The involvement of hydrogen atoms. AB - Comparison of the initial (3)H/(14)C ratios in specifically labelled d-glucose 6 phosphates with the final ratios in myo-inositol produced by glucose 6-phosphate d-myo-inositol 1-phosphate cyclase from rat testis showed that, during the conversion, the hydrogen atoms at C-1 and C-3 were fully retained, one hydrogen atom was lost from C-6, and that at C-5 was apparently retained to the extent of 80-90%. The loss of (3)H could not be stimulated by addition of unlabelled NADH, and when unlabelled substrate was used (3)H from [(3)H]NADH and [(3)H]water was not incorporated. Treatment of the enzyme with charcoal abolished the activity, and this was restored to 25-50% of the original activity by NAD(+). The charcoal treated enzyme again apparently gave 85% retention of hydrogen with [5 (3)H]glucose 6-phosphate as substrate in the presence of NAD(+) alone, but the retention was decreased to 65% with excess of NADH. The results are interpreted as indicating that the cyclization proceeds by an aldol condensation in which C-5 is oxidized by NAD(+) in a tightly-bound ternary complex, and that the apparent loss of (3)H when untreated enzyme is used is due to an isotope effect. It is suggested that after treatment with charcoal some exchange of NADH with an external pool may take place. PMID- 4297938 TI - Specific binding of [14C] piericidin A in the reduced nicotinamide--adenine dinucleotide dehydrogenase segment of the mitochondrial respiratory chain. PMID- 4297939 TI - Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro. AB - 1. A method was devised for the isolation of islets of Langerhans from rabbit pancreas by collagenase digestion in order to study the influx and efflux of K(+) in islets during insulin secretion. 2. Glucose-induced insulin release was accompanied by an increased rate of uptake of (42)K(+) by the islets of Langerhans, though this was not the case for secretion in response to tolbutamide. Ouabain significantly inhibited the uptake of (42)K(+) by islet tissue. 3. No significant increase in the rate of efflux of (42)K(+) was demonstrated during active insulin secretion. 4. Slices of rabbit pancreas were incubated in media of different K(+) content, and rates of insulin release were determined. Alteration of the K(+) concentration of the medium between 3 and 8mm had no effect on the rate of insulin release by pancreas slices. However, decrease of the K(+) concentration to 1mm resulted in inhibition of secretion in response to both glucose and to tolbutamide. Conversely, an increase in K(+) concentration increased rates of insulin release in response to both these stimuli. 5. It is concluded that, though unphysiological concentrations of K(+) may influence the secretion of insulin, fluxes of K(+) in the islets do not appear to be important in the initiation of insulin secretion. PMID- 4297940 TI - Activity of nicotinamide-adenine dinucleotide pyrophosphorylase in liver nuclei. Effects of partial hepatectomy, hepatotoxins and dietary changes. AB - 1. The activity of NAD pyrophosphorylase is lower in nuclei isolated from regenerating rat liver than in normal nuclei, and this is due to leakage of the enzyme from the nuclei during the isolation. 2. The NAD pyrophosphorylase activity is lower in liver nuclei from newborn rats, and from rats on a protein free diet, but no leakage occurs in these cases. 3. Poisoning with alpha-amanitin brings about a transient enhancement of NAD pyrophosphorylase activity in mouse liver nuclei. 4. No changes of enzyme activity were observed after 72hr. starvation, administration of actinomycin D or infection with MHV3 virus. PMID- 4297941 TI - The distribution of monoamine oxidase and alpha-glycerophosphate dehydrogenase in pig brain. AB - Activities of the enzymes monoamine oxidase (EC 1.4.3.4), alpha-glycerophosphate dehydrogenase (EC 1.1.99.5) and cytochrome oxidase (EC 1.9.3.1) were determined in homogenates and in the mitochondrial fraction prepared from individual regions of pig brain. The variation in the activity of alpha-glycerophosphate dehydrogenase paralleled that of cytochrome oxidase, but this was not the case with monoamine oxidase. The differences in the activities of the enzymes among homogenates of the various regions of the brain persisted in mitochondria prepared from these homogenates. The purification of these three enzymes paralleled each other when mitochondria were prepared, suggesting that the three enzymes are bound to the same particles. PMID- 4297942 TI - Relations between conformations and activities of lipoamide dehydrogenase. 3. Protein association-dissociation and the influence on catalytic properties. PMID- 4297943 TI - Kinetic isotope effects in enzymatic oxidations of D-[1-H]glucose and D-[1-2 H]glucose. PMID- 4297944 TI - The sterochemistry of hydrogen transfer catalysed by D(-)-3-hydroxybutyrate dehydrogenase. PMID- 4297945 TI - The localisation of acid phosphatase activity changes in lysosomes in the adrenal zona fasciculata of intact and hypophysectomized rats following ACTH administration. PMID- 4297946 TI - The specific cytochemical demonstration in the electron microscope of periodate reactive mucosubstances and polysaccharides containing vic-glycol groups. PMID- 4297947 TI - Antibodies against Enteroviruses in different age groups. PMID- 4297948 TI - Electrolyte alterations in vascular smooth muscle and hypotensive activity of a new chalcone derivative. PMID- 4297949 TI - New developments in antibiotic interference thresholds of microbial assays. PMID- 4297950 TI - [Cases of gas gangrene treated with hyperbaric oxygen]. PMID- 4297951 TI - [On an episode of alimentary toxinfection caused by Cl. perfringens]. PMID- 4297952 TI - [Synovial sarcoma]. PMID- 4297953 TI - A virilizing adrenal tumor with borderline elevation of urinary 17-ketosteroids. PMID- 4297954 TI - The natural history of cirrhosis. Experience with an unselected group of patients. PMID- 4297955 TI - Myopathy associated with pigmentation following adrenalectomy for Cushing's syndrome. PMID- 4297956 TI - Renin, angiotensin, corticosteroids, and electrolyte balance in Addison's disease. PMID- 4297957 TI - [How to treat gout]. PMID- 4297958 TI - [The behavior of enzymes in Euglena gracilis. 1]. PMID- 4297959 TI - [The diagnostic value of glutamic acid dehydrogenase]. PMID- 4297960 TI - Evidence for the release and depletion of the postsynaptic inhibitory transmitter by pilocarpine. PMID- 4297962 TI - [The influence of skin transplantation on the success of a syndactylia operation]. PMID- 4297963 TI - General base catalysis in the reactions of transfer ribonucleic acid ligases. PMID- 4297964 TI - Purification and partial characterization of collagenolytic enzymes from Clostridium histolyticum. PMID- 4297965 TI - Sulfenyl halides as modifying reagents for polypeptides and proteins. I. Modification of tryptophan residues. PMID- 4297967 TI - Nicotinamide adenine dinucleotide kinase from Azotobacter vinelandii cells. Reversible inactivation of the enzyme. PMID- 4297966 TI - Purification, properties and mechanism of interconversion of kidney phosphorylase. PMID- 4297969 TI - Pseudocollagenase: a protease from Clostridium histolyticum. PMID- 4297968 TI - Stereospecificity of hydrogen transfer by bovine adrenal 3 beta-hydroxysteroid dehydrogenase. PMID- 4297961 TI - [Vasoactive substances belonging to the body and pharmacologic agents with peripheral point of application]. PMID- 4297970 TI - [Change in the electron paramagnetic resonance spectrum of animal tissue during heat treatment]. PMID- 4297971 TI - [Model representations of the organization of synapses on neuron dendrites for memory of signals with different impulse and interval ratios]. PMID- 4297972 TI - [Kinetic character of two interconvertible forms of pyruvate kinase in the human erythrocyte]. PMID- 4297973 TI - [Local interactions of cells in cell complexes of ascitic hepatoma 22]. PMID- 4297974 TI - [Adrenocorticotropic factor synthesis by cell-free system of Escherichia coli B, under the effect of ribonucleic acid from bovine adenohypophyses]. PMID- 4297975 TI - [Study of interoceptive impulsation in puppies by electroencephalography]. PMID- 4297976 TI - [Thin layer chromatographic separation of porphyrins, hemin and lipids on Silica Gel H plates for the determination of the erythrocyte porphyrins as their methyl esters]. PMID- 4297977 TI - Quantitative analysis of rat liver phospholipids by a two-step thin-layer chromatographic procedure. PMID- 4297978 TI - The painful tumours of the skin. PMID- 4297979 TI - Ischemic mononeuropathy and mononeuropathy multiplex in diabetes mellitus. PMID- 4297980 TI - Control of cardiac-muscle contraction. PMID- 4297981 TI - [Late surgery for sequelae of the ischemic syndrome]. PMID- 4297982 TI - [Diagnostic and therapeutic value of selective carotid angiography in a case of nasopharyngeal hemangiofibroma of male puberty]. PMID- 4297983 TI - [Ossification disorders in treated hypothyreosis]. PMID- 4297984 TI - [Reichstein's S substance in humans]. PMID- 4297985 TI - [On 2 cases of tympano-jugular tumors]. PMID- 4297986 TI - [Remote follow-up of visual function of patients operated on for pituitary adenoma. Study of 20 cases]. PMID- 4297987 TI - [Considerations on mixed tumors of the salivary glands]. PMID- 4297988 TI - [Serum growth hormone levels in patients with brain tumors]. PMID- 4297989 TI - [Tumors of the brain in patients with diseases of the major blood vessels of the head]. PMID- 4297990 TI - [On hypoglycemic conditions simulating tumors and vascular diseases of the brain]. PMID- 4297991 TI - [On the pathogenesis of endocrine disorders in the slow development of occlusive hydrocephalus of neoplastic and inflammatory origin]. PMID- 4297992 TI - [The importance of after-treatment and after care of tuberculosis patients following discharge from the sanatorium]. PMID- 4297993 TI - [The determination of the tryptophan-perchloric acid reaction (TPR) and the serum LDH for the control of gynecologic carcinoma therapy with special consideration of cytostatic therapy]. PMID- 4297994 TI - [Role of Soviet neuropathologists in developing the semeiotics of sensory and motor disorders]. PMID- 4297995 TI - [Development of Soviet neurologic semeiology]. PMID- 4297996 TI - Experimental evaluation of the threshold limit of cristobalite--calcined diatomaceous earth. PMID- 4297997 TI - Quantitative determination of phosphatidal ethanolamine and other phosphatides in various tissues of the rat. PMID- 4297998 TI - [Immunologic determination of ACTH]. PMID- 4298000 TI - [Considerations of the values of plasma corticotropic activity and their variations under the influence of various treatments in 8 cases of Cushing's disease]. PMID- 4297999 TI - [Aspects of the metabolism of cortisol and cortexolone (or of compound S) in the normal condition and in Cushing's disease]. PMID- 4298001 TI - [Studies on the secretion and metabolism of cortisol in obesity and Cushing's disease]. PMID- 4298003 TI - Behavior of poliovirus towards dextran sulphate and relationship between this character and other genetic markers. PMID- 4298002 TI - [Suprahypophyseal orgin of Cushing's disease. Therapeutic deductions]. PMID- 4298004 TI - [Study of the hepatic phospholipids in induced steatosis by carbon tetrachloride]. PMID- 4298005 TI - Paramagnetic anisotropy measurements on acid ferrimyoglobin and ferrimyoglobin fluoride. PMID- 4298006 TI - Degradation of angiotensin II by a carboxypeptidase of rabbit liver. PMID- 4298007 TI - Differences in turnover between histones and their acetyl N-terminal groups. PMID- 4298008 TI - Specific unmasking of ribosomal proteins under the influence of chelating agents and increased ionic strength. PMID- 4298009 TI - [Peripheral neuropathy in familial primary amyloidosis, with special reference to 10 cases in one family and a review of the literature]. PMID- 4298010 TI - [Intervention of a nuclease in the inhibitory action of supra-optimal temperatures on the development of a poliovirus]. PMID- 4298011 TI - [Destruction of cellular sensitivity to the action of an exogenous interferon after infection by the leukemia-sarcoma complex virus of the mouse]. PMID- 4298012 TI - [Enzymatic conversion of n-butyraldehyde to n-butanol in Clostridium acetobutylicum]. PMID- 4298013 TI - The reduction of SU-4885 by adrenal glands and other tissues and its inhibition by ACTH. PMID- 4298014 TI - [IR demonstration of some drugs after thin layer chromatography, preparative purification and isolation]. PMID- 4298015 TI - [Treatment with massive doses of synthetic corticoids and hypothalamopituitary adrenocortical function with reference to acute leukemia]. PMID- 4298017 TI - [Autopsy case of Cushing's syndrome caused by malignant thymoma]. PMID- 4298016 TI - [Studies on the mechanism of ACTH-secretion with special reference to the bioassay of C.R.F. in vitro]. PMID- 4298018 TI - [Case of anterior pituitary hyperplasia following adrenalectomy in Cushing's syndrome]. PMID- 4298019 TI - [Studies on the functional position of the zona glomerulosa in the adrenal cortex during the blockade of 18-hydroxylation with SU 5482]. PMID- 4298020 TI - [Drop-like storage of fluorescent-dye labeled protein corpuscles in the proximal kidney tubules]. PMID- 4298021 TI - Enzyme histochemical investigations of the inhibitory effect of zinc on the injurious action of carbon tetrachloride on the liver. PMID- 4298022 TI - [Enzymatic studies on glomerular basement membranes]. PMID- 4298023 TI - [Integration of mitochondrial respiration and cytoplasmic glycolysis]. PMID- 4298024 TI - [On a case of mucoepidermoid tumor of the palate]. PMID- 4298025 TI - [On the concept and histogenesis of mixed tumors. Considerations on 3 cases of neoplastic disease of the minor glands of the oral cavity]. PMID- 4298026 TI - [The aphthoses of the mouth mucosa]. PMID- 4298027 TI - [Obesity and diabetic disease]. PMID- 4298028 TI - [Study of the correlation between length of history of obesity and reduction of glucose tolerance]. PMID- 4298029 TI - [Hypopituitarism occurring in a hyperthyroidism patient 4 years after an intrasellar isotopic treatment]. PMID- 4298030 TI - [Bilateral hematomas of the adrenal glands. Complication of anticoagulant treatment. (Apropos of 1 further anatomo-clinical case]. PMID- 4298031 TI - [The mode of action of the hypoglycemic sulfamides]. PMID- 4298032 TI - [A gene dysplasia not previously known: frequently degenerative sclero-atrophying and keratodermic genodermatosis of the extremities]. PMID- 4298034 TI - [Auriculo-ventricular block with ventricular hyperexcitability and Adams-Strokes syndrome. Emergency treatment]. PMID- 4298033 TI - [Scleroderma with diffuse myocardial and vascular lesions]. PMID- 4298035 TI - [Electrophoresis on cellulose acetate in the diagnosis of hemoglobinoses in Abidjan]. PMID- 4298036 TI - [The mosaic XY-XXY]. PMID- 4298038 TI - [Contribution to the study of the pathogenesis of diverticuloses and their morbid associations]. PMID- 4298037 TI - [Apropos of l case of Moschcowitz's disease]. PMID- 4298039 TI - Effect of whole-body gamma-irradiation on the subcellular distribution of proteinases in rat thymus. PMID- 4298040 TI - [Renin-angiotensin-system and intrarenal vascular resistance]. PMID- 4298042 TI - [Excretion of individual steroid in various forms of hypocorticism]. PMID- 4298041 TI - [Pituitary tumors in children and adolescents]. PMID- 4298043 TI - [Total syndactylia and total radioulnar synostosis in 2 brothers. A contribution on the genetics of syndactylia]. PMID- 4298044 TI - [On clinical aspects of primary lung sarcoma]. PMID- 4298046 TI - [On the pathogenesis of chronic diencephalic syndromes of infectious etiology]. PMID- 4298045 TI - [The immediate and remote sequelae of serous viral meningitis]. PMID- 4298047 TI - [The pathogenesis of rheumatic diseases with nervous system diseases. Acute and chronic rheumatic pachy-leptomeningo-encephalitis, myelitis and rheumatic sclerosis of the brain and spinal cord]. PMID- 4298048 TI - [Psychological disturbances in influenza]. PMID- 4298050 TI - Medical problems from Vietnam. PMID- 4298049 TI - [On the course of drug psychoses]. PMID- 4298051 TI - Residual ethiodol after lymphography in diagnosis of lymphoma. PMID- 4298052 TI - Chloroquine neuromyopathy. PMID- 4298053 TI - Release of chronic psychiatric patients into the community. PMID- 4298054 TI - A case of adult coeliac disease resistant to treatment. PMID- 4298055 TI - Urethan carcinogenesis and nucleic acid metabolism: in vitro interactions with enzymes. PMID- 4298056 TI - Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck. PMID- 4298057 TI - The influence of transplantable rat mammary carcinomas and the Walker carcinoma 256 on the lipid composition of the muscle and liver of the host. PMID- 4298058 TI - The nucleolar RNA of minimal deviation hepatomas. PMID- 4298059 TI - Particles resembling murine leukaemia virus in New Zealand black mice. PMID- 4298060 TI - The cytochemical localization of glucose-6-phosphatase within the liver of the developing chick embryo. PMID- 4298061 TI - Collagenolytic activity in regenerating forelimbs of the adult newt (Triturus viridescens). PMID- 4298062 TI - Lesch-Nyhan syndrome. Pathology and pathologic physiology. Summary. PMID- 4298063 TI - Possible mechanism for increased purine biosynthesis de novo in Lesch-Nyhan syndrome. PMID- 4298064 TI - Possible functions of hypoxanthine-guanine phosphoribosyltransferase and their relation to the biochemical pathology of the Lesch-Nyhan syndrome. PMID- 4298065 TI - Lesch-Nyhan syndrome. Management and treatment. PMID- 4298067 TI - Transfer of defective Rous sarcoma virus genome from Chinese hamster embryonic cells to chicken cells. PMID- 4298066 TI - Rational approaches to the treatment of the Lesch-Nyhan syndrome. PMID- 4298068 TI - Study of antibodies induced in rabbits in the process of viral carcinogenesis. PMID- 4298069 TI - Isolation of encephalomyocarditis (EMC) virus strains in India. PMID- 4298070 TI - The regulation of fatty acid biosynthesis in rat hepatomas. PMID- 4298071 TI - A phospholipase specific for sphingomyelin from Clostridium perfringens. PMID- 4298072 TI - An adenosine 3',5'-monophosphate-dependant protein kinase from rabbit skeletal muscle. PMID- 4298073 TI - Enzymic adenosine diphosphate ribosylation of histone and poly adenosine diphosphate ribose synthesis in rat liver nuclei. PMID- 4298074 TI - 5'-adenylyl-O-tyrosine. The novel phosphodiester residue of adenylylated glutamine synthetase from Escherichia coli. PMID- 4298075 TI - The detection and identification of intermediates of the pentose phosphate cycle and related compounds. PMID- 4298076 TI - Increased sensitivity of the thyroid in iodine-depleted rats to the goitrogenic effects of thyrotropin. AB - The present studies demonstrate that iodine depletion increases the sensitivity of the thyroid to the goitrogenic effects of thyrotropin. Iodine depletion was induced by feeding rats a low iodine diet containing propylthiouracil for 10-14 days before hypophysectomy. Accumulation of iodine in the thyroid after hypophysectomy was prevented by continuing the antithyroid drugs in the diet. Doses of thyrotropin as low as 3 mU/100 g of body weight per day produced significant thyroid enlargement in 3-7 days in iodine-depleted rats. Adding propylthiouracil or perchlorate to the diet during treatment with thyrotropin did not reduce or augment the goitrogenic response to thyrotropin in iodine-depleted rats. Increasing the level of circulating iodide also did not reduce the goitrogenic response to thyrotropin. The increased sensitivity of the iodine depleted thyroid gland may provide an explanation for the development of thyroid enlargement without requiring an increased level of circulating thyrotropin. PMID- 4298077 TI - Effect of norepinephrine, epinephrine, and angiotensin on blood flow in the internal carotid artery of man. AB - Internal carotid artery blood flow and arterial pressure were measured with a sine-wave electromagnetic flowmeter and a pressure transducer in 22 patients during control period and after the intravenous and intracarotid administration of norepinephrine, epinephrine, and angiotensin. Intravenous infusion of both norepinephrine and angiotensin was accompanied by an increase in cerebral vascular resistance. Administration of norepinephrine, epinephrine, and angiotensin into the internal carotid artery failed to alter blood flow immediately. However, when the systemic blood pressure increased, a concomitant passive rise in blood flow did not occur. Thus, at this time cerebral vascular resistance was significantly increased. It is concluded that these drugs do not have a direct action on the cerebral vessels, but that the increased cerebral vascular resistance after their administration is due to autoregulation or to a combination of autoregulation and reduced arterial carbon dioxide pressure (P(CO2)) secondary to hyperventilation. Similar studies were carried out in the external carotid artery of six patients. Within 10 sec after injection blood flow was markedly reduced, indicating a direct vasoconstricting action on this vascular bed. PMID- 4298078 TI - Antibody to human follicle-stimulating hormone: cross-reactivity with three other hormones. AB - Antibodies directed against human follicle-stimulating hormone (FSH) were demonstrated in rabbit serum by neutralization of biological activity. Antibodies that bound FSH-(131)I were produced in rabbits and guinea pigs by repeated injections of FSH. By (131)I immunochemical methods, we found that at least 90% of the FSH-(131)I-binding antibody failed to distinguish the four human glycoprotein hormones: FSH, luteinizing hormone, chorionic gonadotropin, and thyrotropin, purified as well as endogenous hormone in plasma. Neither growth hormone, adrenocorticotropin, nor a variety of glycoproteins or animal plasmas were able to react with these antibodies. PMID- 4298079 TI - [Diet therapy of diseases of the digestive organs: with special reference to the fat diet for the diseases of the biliary tracts and the liver]. PMID- 4298080 TI - Sertoli cell tumor (androblastoma): a case report. PMID- 4298081 TI - SV40-transformed hamster prostatic tissue: a model of human prostatic malignancy. PMID- 4298082 TI - [Enzymatic histochemistry of the rat nephron]. PMID- 4298083 TI - Histochemical and histoenzymological studies of tibial growing cartilage in pituitary dwarfism. PMID- 4298085 TI - [Study of the distribution of drug resistant forms of causative aents of dysentery in Dnepropetrovsk]. PMID- 4298084 TI - [Histochemical study of visual cells in the chicken]. PMID- 4298086 TI - [Study of the action of ethyleneimines, ultraviolet rays and their combination on the producent of florimycin --Act. floridae strain 4024]. PMID- 4298087 TI - [Chemical method for determination of ristomycin]. PMID- 4298089 TI - [Cytomorphological and enzymocytochemical studies of tissue cultures treated with pertussis toxin]. PMID- 4298088 TI - [Study of the action of polymyxin M on dysentery bcteria in experimental and clinical conditions according to data from Gomel]. PMID- 4298091 TI - [Evaluation of the bone age in children with primary and secondary cleft palate]. PMID- 4298090 TI - [Pituitary-adrenal correlation]. PMID- 4298092 TI - [Cause of presumed ischialgias: non-traumatic stricture of the peroneal nerve]. PMID- 4298093 TI - [Characterization of peroxidase as a component of the oxidative system in plants]. PMID- 4298094 TI - [The characteristics of glycerophosphatase of Clostridium perfringens]. PMID- 4298095 TI - [On the mechanism of variation in the sensitivity of organs to physiologically active substances, accompanying changes in the concentration of hormones in the organism]. PMID- 4298096 TI - [Some problems of information transmission along the nerve fiber]. PMID- 4298097 TI - [An etiologic and anatomo-pathologic contribution to the study of glioblastoma multiforme (with a presentation of a personal case observed in a six year old child)]. PMID- 4298098 TI - [Histopathologic considerations in a case of generalized cytomegaly]. PMID- 4298099 TI - [On the diuretic and antidiuretic power of a sulfato-alkalino-silicic, medio mineral thermal water in subjects of various ages (water of Val Masino)]. PMID- 4298100 TI - [Morphologic studies of the rabbit's inguinal gland. II. Histochemistry of oxydoreductases]. PMID- 4298101 TI - A method for the electron microscopic demonstration of cytochrome oxidase in fresh and formalin-prefixed tissues. PMID- 4298102 TI - Enzyme histochemistry of the mesenteric and dorsal root ganglion cells of cat and squirrel monkey. PMID- 4298103 TI - Electron microscope studies of phosphatases in the small intestine of Rana temporaria during larval development and metamorphosis. PMID- 4298105 TI - Enzyme activities as electron microscopic markers of bile and bile thrombi in the study of cholestasis. PMID- 4298104 TI - [Enzyme histochemical studies of the nervous system. I. The content of some oxidoreductases in the cerebral ganglion of the earthworm (Eisenia foetida) with special consideration of the neurosecretory system]. PMID- 4298106 TI - [Relationship of invasive amebiasis to the liver, biliary tract and gallbladder]. PMID- 4298107 TI - [On formation of lysolecithin owing to intracellular damage by quartz dust]. PMID- 4298109 TI - [Studieson biological radiation protection. 75. Studies on the effect of cysteine and methionine on the formation of free radicals in freeze-dried rat liver]. PMID- 4298110 TI - Thrombocytopenia in guinea pigs infected by encephalomyocarditis virus (EMC). PMID- 4298108 TI - [Functional and morphological changes in the rat kidney following local irradiation]. PMID- 4298111 TI - [Growth characteristics of various neuroectodermal tumors and human embryonic brain in monolayer cultures]. PMID- 4298112 TI - [On the problem of ovulation stimulation by intravenously administered estrogens]. PMID- 4298113 TI - [Peculiar aspect of the reflex defense reactions in focal disorders of the structure of the hippocampal formation]. PMID- 4298114 TI - Histochemical and histoenzymological study of tibial growing cartilage in Hurler's syndrome. PMID- 4298115 TI - Comparative physiology of serotonin and melatonin. PMID- 4298116 TI - [On the neurotropic behavior of foot-and-mouth disease standard A virus after intracerebral inoculation. 3. Development of a virus strain with neurotropic properties for the guinea pig]. PMID- 4298117 TI - [A simple method for the enrichment of virus in tissue culture fluid by adsorption on calcium phosphate]. PMID- 4298118 TI - [Studies on the population composition of foot-and-mouth disease virus during the course of a modification in the central nervous system of mice]. PMID- 4298119 TI - [Familial episode of Reovirus type I infection of an enteritic nature]. PMID- 4298120 TI - Pelvic arteriography in invasive trophoblastic neoplasia. PMID- 4298121 TI - Idiopathic facial palsy. PMID- 4298123 TI - Differences in the growth-promoting effect of normal and peritumoral dermis on epidermis in vitro. PMID- 4298122 TI - Hereditary hemolytic anemias associated with specific erythrocyte enzymopathies. PMID- 4298124 TI - Aberrations in pulmonary function due to lymphangiography. PMID- 4298125 TI - Organic phosphorus mineralization and phosphatase activity in soils. PMID- 4298126 TI - Growth and age-classes in the prairie vole, Microtus ochrogaster. PMID- 4298127 TI - Weight of bone in the fetus--a preliminary report. PMID- 4298128 TI - [Rare picture of a fibromyxoepithelioma of the pterygopalatine fossa]. PMID- 4298129 TI - The properties, developmental formation, and estrogen induction of ornithine aminotransferase in rat tissues. PMID- 4298130 TI - A method for the separation of cyclic adenosine 3',5'-monophosphate from other adenine nucleotides by high voltage ionophoresis on paper. PMID- 4298131 TI - [Sero-epidemiological study on neutralizing antibody against Adenovirus type-3 in school children after an outbreak of pharyngo-conjunctival fever]. PMID- 4298132 TI - [Neutralizing antibody titer against Japanese encephalitis virus in healthy adults living in Kumamoto prefecture]. PMID- 4298133 TI - [Pathological observation on an acute case of polyradiculoneuropathy having cranial and spinal paralysis]. PMID- 4298134 TI - Mass enteric live adenovirus vaccination during epidemic ARD. PMID- 4298135 TI - [Demonstration of varicella-zoster virus in ultrathin sections]. PMID- 4298136 TI - Endocrine syndromes associated with pancreatic islet cell tumors. PMID- 4298138 TI - [The value of lymphography in the diagnosis and therapy of malignant lymphogranuloma]. PMID- 4298137 TI - [Adrenal cortex physiopathological aspects of complicated gastric and duodenal ulcers]. PMID- 4298139 TI - Immunization against respiratory virus infections. PMID- 4298140 TI - [An electron microscopic study on the central nervous system of mice with experimental Japanese encephalitis]. PMID- 4298141 TI - [Hyspsarrhythmia and spasm in flexor treated by cortrophin Z. Study of 8 cases]. PMID- 4298142 TI - Cyclic 3',5'-adenosine monophosphate phosphodiesterase produced by the slime mold Dictyostelium discoideum. AB - An enzyme that hydrolyzes cyclic ',5'-adenosine monophosphate to 5'-adenosine monophosphate was found in the culture medium of the cellular slime mold Dictyostelium discoidum. The enzymatic activity shows a pH optimum of 7.5, and magnesium is required for maximum activity. The enzyme is not inhibited by caffeine. It has a Michaelis-Menten constant of 2 x 10(-3)M and its molecular weight is around 300,000. PMID- 4298143 TI - [Research on the presence of antibodies against viruses of the groups A, B, and D (Bunyamwera) in inhibitants of the Oltenia region]. PMID- 4298144 TI - [Diagnostic significance of secretion from the mammary papilla]. PMID- 4298145 TI - [Review. Physiopathology and treatment of urolothiasis]. PMID- 4298146 TI - [Old and new on butter yellow]. PMID- 4298147 TI - The vascularization of the hypothalamic-hypophyseal region of the Eastern Brook Trout, Salvelinus fontinalis. PMID- 4298148 TI - The effects of essential fatty acid deficiency on the skin of the mouse. PMID- 4298149 TI - [On the significance of spirometric examinations prior to bran surgery and their therapeutic consequences in the postoperative phase]. PMID- 4298150 TI - Observations on the growth andregression of Rous sarcoma in rats and mice of a non-inbred strain. PMID- 4298151 TI - A comparative study of arteriography and scintillation scanning in space occupying leions of the liver. PMID- 4298152 TI - [Epizootiology and prevention, in the territory of the Federal Republic of Germany, of virus diseases of cattle affecting the mucous membranes]. PMID- 4298153 TI - The mucosal diseases in the Netherlands. PMID- 4298154 TI - [Growth of the aphthous virus in dispersed cell cultures; new possibility of obtaining a high infectious titer]. PMID- 4298156 TI - [Hyde's nodular prurigo]. PMID- 4298155 TI - Avian leukosis. PMID- 4298159 TI - [Relation between time of appearance of tumors and dose of injected cells in a polyomahamster system]. PMID- 4298158 TI - [Alterations of ultrastructure of the aortic wall of the rabbit after atherogenic treatment: preventive action of a silicium derivative]. PMID- 4298157 TI - [Action of a methanolic extract from Amanita phalloides upon cultivated hepatocytes. I. Glycogen and glucose-6-phosphatase variations]. PMID- 4298160 TI - Effects of corticosterone on oxidative metabolism in different tissues of the rat. PMID- 4298162 TI - Experimental opacification of the substernal lymph nodes in animals. PMID- 4298161 TI - Response of "prolactin-secreting" cells of Tilapia mossambica to environmental salinity. PMID- 4298163 TI - [Results of irradiation of rectal carcinomas 1952-1963]. PMID- 4298164 TI - Helminths as vehicles and synergists of microbial infections. PMID- 4298165 TI - [On the pathogenesis of complications of cerebral angiography in several types of neuroectodermal tumors]. PMID- 4298166 TI - [Neoformation of vessels in glioblastoma multiforme]. PMID- 4298168 TI - [Cytological impressions from the wound surface after excision of brain tumors]. PMID- 4298167 TI - [Dynamics of neurological symptoms in patients with brain tumors during combined therapy (operation plus betatron electromagnetic radiation)]. PMID- 4298169 TI - Amphotericin B therapy in the treatment of presumed histoplasma chorioretinitis. A further appraisal. PMID- 4298170 TI - Metabolism and blood levels following infusion of a radioactive analog of angiotensin. PMID- 4298171 TI - Deterministic nature of baroreceptor firing. PMID- 4298172 TI - Kinetics of renin-angiotensinogen reaction in plasma of normal and nephrectomized rats. PMID- 4298173 TI - Hemagglutinating activity of enteroviruses recovered in two primary cell lines and a stable line. AB - A microhemagglutination technique was used to detect hemagglutinating properties of enteroviruses recovered in two primary cell lines, monkey kidney (MK) and human amnion (HAm), and in a continuous cell line, human embryonic lung (HEL). During a 3-year period, 1,528 isolations of enteroviruses were tested for hemagglutinating activity and hemagglutination inhibition response; 96.3% of the viruses were also identified by virus neutralization tests. Enteroviruses recovered in HEL were far less likely to develop hemagglutinins than viruses isolated in MK or HAm. Of the enteroviruses known to agglutinate human type O cells, 77.8% of the primary viral isolates from MK, 62.1% of the isolates from HAm, and 20.3% of the isolates from HEL exhibited this property. An additional 8.1% of the isolations obtained in HEL hemagglutinated human cells after a single passage in MK. The microhemagglutination technique using microtiter equipment was simple to perform, saved time and valuable typing sera, and helped to obtain identifications rapidly. PMID- 4298174 TI - Angiotensin-infusion test. Correlation with renin activity in peripheral venous blood. PMID- 4298176 TI - Mucoepidermoid carcinoma of the parotid gland. PMID- 4298175 TI - Postabortal septicemia due to Clostridium welchii. Treatment with exchange transfusion. PMID- 4298177 TI - Clear cell hidradenoma of the breast. PMID- 4298178 TI - Primary hepatocellular carcinoma in three male siblings. PMID- 4298179 TI - Survival in males with surgically treated localized cancer of the lung. PMID- 4298180 TI - Ultrastructure of the chondroid regions of benign mixed tumor of salivary gland. PMID- 4298181 TI - The development defects associated with neuroblastoma--etiologic implications. PMID- 4298182 TI - Mesenchymal hamartoma of the liver. PMID- 4298183 TI - Effect of fluoride on the metabolic activity of thyroid slices. PMID- 4298184 TI - Acute effects of angiotensin-II-amide on aldosterone and corticosterone secretion by morphine-pentobarbital treated rats. PMID- 4298185 TI - Effects of small doses of thyroid hormones on thyroid weight in hypothyroid rats. PMID- 4298186 TI - Inhibition of adrenal cortical secretion by amino-glutethimide in dogs. PMID- 4298187 TI - Marmoset liver organ culture infected with herpes virus. PMID- 4298188 TI - The management of facial palsy. PMID- 4298189 TI - Brachial plexus avulsion. A review of diagnostic procedures and report of six cases. PMID- 4298190 TI - Nerve root conduction studies during lumbar disc surgery. PMID- 4298191 TI - [Bovine enteroviruses. 2. Neutralizing antibodies in the sera of cattle from Kenya]. PMID- 4298192 TI - Electrophoretic mobility of isolated nuclei from rat ascites hepatoma cells and normal liver cells. PMID- 4298193 TI - Examination of fibres in beer. PMID- 4298194 TI - Diffusion of antibiotics from plasma into prostatic fluid. PMID- 4298195 TI - Photoparamagnetism in solid nucleic acid-cationic dye complexes. PMID- 4298196 TI - Tumour production in adult mice by syngeneic embryonic cultured cells containing the incomplete Rous virus. PMID- 4298197 TI - Influence of efferent fibres on a receptor. PMID- 4298199 TI - Virology: United States-Soviet Health Exchange visit 1967. PMID- 4298198 TI - Electron spin resonance in organic chemistry. Determination of structure and conformation of paramagnetic substances is demonstrated. PMID- 4298200 TI - Spinal cord lesions and rehabilitation: Review of cases discharged from the Duke Medical Center, Neurosurgical Division (1959-1964). PMID- 4298201 TI - Diagnostic value of the simultaneous determination of urinary free and conjugated cortisol in Cushing's syndrome. PMID- 4298202 TI - Current problems in the use of the oncolytic drugs. PMID- 4298203 TI - Monkeypox: experimental infection in chimpanzee (Pan satyrus) and immunization with vaccinia virus. PMID- 4298204 TI - Tissue fractionation and catecholamines. II. Intracellular distribution patterns of tyrosine hydroxylase, dopa decarboxylase, dopamine-beta-hydroxylase, phenylethanolamine N-methyltransferase and monoamine oxidase in adrenal medulla. PMID- 4298205 TI - Sites of impulse formation within the atrioventricular junction of the rabbit. PMID- 4298206 TI - Changes in sodium balance and hemodynamics during development of experimental renal hypertension in dogs. PMID- 4298207 TI - Effects of sympathetic nerve stimulation on the pulmonary arterial tree of the isolated lobe perfused in situ. PMID- 4298208 TI - [Studies on lytic and non-lytic response of the cells infected with polyoma virus]. PMID- 4298209 TI - [Influence of polyoma virus on the tooth buds]. PMID- 4298211 TI - [Information processing in lower animals]. PMID- 4298212 TI - [Information processing in the central nervous system]. PMID- 4298210 TI - The correlation of the fasting serum tyrosine level to the clinical status of patients with rheumatoid arthritis. PMID- 4298213 TI - Endocrine factors in congestive heart failure. PMID- 4298214 TI - A rapid radioimmunoassay for human placental lactogen. Application to normal and pathologic pregnancies. PMID- 4298215 TI - Ambiguous genitals in a female infant associated with luteoma of pregnancy. Report of a case. PMID- 4298216 TI - Effect of an intrauterine contraceptive device on biochemical composition of uterine fluid. PMID- 4298217 TI - Glomus jugulare tumors. I. Historical background. PMID- 4298218 TI - Treatment of malignant tumors of minor salivary glands. PMID- 4298219 TI - The kinetics of cyanide and fluoride binding by ferric horseradish peroxidase. PMID- 4298220 TI - Evidence for an acid-catalyzed alpha,beta epimerization in pyridine nucleotides. PMID- 4298221 TI - Mechanisms of the primary acid modification reaction of reduced diphosphopyridine nucleotide models. PMID- 4298222 TI - On the localization of alkaline phosphatase and cyclic phosphodiesterase in Escherichia coli. PMID- 4298223 TI - Purification and properties of the luciferase and of a protein cofactor in the bioluminescence system of Latia neritoides. PMID- 4298224 TI - Inosine 5'-phosphate dehydrogenase. Kinetic mechanism and evidence for selective reaction of the 6-chloro analog of inosine 5'-phosphate with a cysteine residue at the inosine 5'-phosphate site. PMID- 4298225 TI - A simple method for isolating highly purified yeast phenylalanine transfer ribonucleic acid. PMID- 4298226 TI - Oxidative degradation of aromatic hydrocarbons by microorganisms. I. Enzymatic formation of catechol from benzene. PMID- 4298227 TI - Spin-labeled hemoglobin subunits. PMID- 4298228 TI - Kinetics of coupled enzymes. Creatine kinase and myosin A. PMID- 4298229 TI - Fatty acid biosynthesis. IV. Properties of acetyl-CoA carboxylase in lactating rabbit mammary gland. PMID- 4298230 TI - Effect of sphingomyelinase from Clostridium perfringens on the metabolic activity and phospholipid composition of thyroid slices. PMID- 4298232 TI - Separation of sphingosine, dihydrosphingosine and phytosphingosine by chromatography on columns of silica gel. PMID- 4298231 TI - Effects of myo-inositol deficiency upon the lipid composition of the yeast, Saccharomyces carlsbergensis. PMID- 4298233 TI - Factors affecting the synthesis of 2,3-diphosphoglycerate in hemolysates of human erythrocytes. PMID- 4298234 TI - Studies on the biosynthesis of nicotinamide-adenine dinucleotide in the brain. PMID- 4298235 TI - The concentration of HCG in the plasma and spinal fluid of patients with trophoblastic tumours in the central nervous system. PMID- 4298236 TI - Effect of splenectomy on hepatic tumorigenesis. A morphological study. PMID- 4298237 TI - A study of the interdependence of red cell and bone marrow stem cell populations. PMID- 4298238 TI - The role of sensory nerve endings in neurogenic inflammation induced in human skin and in the eye and paw of the rat. PMID- 4298239 TI - Effect of angiotensin on the response to noradrenaline and sympathetic nerve stimulation, and on 3H-noradrenaline uptake in cat mesenteric blood vessels. PMID- 4298240 TI - Angiotensin in the analysis of the intrinsic nerve supply of isolated intestines. PMID- 4298241 TI - Removal of angiotensins from the systemic circulation. PMID- 4298242 TI - Effectiveness of radiation therapy in the management of sarcoma of the soft somatic tissues. PMID- 4298243 TI - Ultrastructural studies in Wilms's tumor. PMID- 4298244 TI - [Orofaciodigital syndrome. Clinical features and genetics]. PMID- 4298245 TI - [Roentgenologic diagnosis of postgastrectomy syndrome and postoperative ulcer]. PMID- 4298246 TI - Electrodiagnosis of polyneuropathy. PMID- 4298247 TI - [Possibilities for the use of thermography]. PMID- 4298248 TI - Measurement of testosterone and 17-ketosteroids in plasma by the double isotope dilution derivative technique. PMID- 4298250 TI - C3H-Avy--a high hepatoma and high mammary tumor strain of mice. PMID- 4298249 TI - Auditory detection and perception in normal man and in patients with adrenal cortical insufficiency: effect of adrenal cortical steroids. AB - Auditory detection thresholds for sinusoidal tones and various tests of auditory perception were determined in 12 patients with adrenal cortical insufficiency (seven with Addison's disease and five with panhypopituitarism) and compared to those in normal volunteers. In adrenal cortical insufficiency auditory detection sensitivity was significantly more acute than normal, and judgments of loudness and of the contralateral threshold shift were made at levels more than 20 db below those of normal subjects. Thus both the lower and the upper limits of the dynamic auditory range are significantly decreased in these patients. Speech discrimination ability of the patients was significantly impaired as was their difference limens, their alternate binaural loudness balances, and their ability to localize tones in space. Treatment of the patients with deoxycorticosterone acetate decreased serum potassium concentration, raised serum sodium concentration, and produced gains in body weight but did not alter auditory detection or perception. Treatment with prednisolone or with maintenance doses of carbohydrate-active steroids returned auditory detection and perception to normal in every patient tested. The inability of the untreated patients to perform the various auditory perception tasks indicates that they have a defect in their ability to integrate incoming sensory stimuli. This defect may be related to the alteration in the timing of transmission of neural impulses along axons and across synapses which occurs in these patients when their carbohydrate-active steroid is removed. This decreased integrative capacity occurs at the same time that they are able to detect many types of sensory stimuli significantly better than normal subjects. This interrelationship between increased detection sensitivity and decreased perceptual ability is dependent upon the absence of carbohydrate-active steroids, for when these steroids are replaced both detection sensitivity and perceptual ability revert to normal. PMID- 4298251 TI - Susceptibility of mammary tissues of different strains of mice to tumor development. PMID- 4298252 TI - Influence of mammary tumor virus on the tumor-producing capabilities of nodule outgrowth free of mammary tumor virus. PMID- 4298253 TI - Propagation of the mammary tumor agent (Bittner virus) in the absence of mammary glands in mice. PMID- 4298254 TI - Time of appearance of viral activity in red blood cells of mice infected naturally or artificially with mammary tumor virus. PMID- 4298255 TI - Biological properties of B particles from C3H and C3Hf mouse milk. PMID- 4298256 TI - Immunology of the mouse mammary tumor virus (MTV). Electron microscopic studies of interaction between MTV and specific antibody in immunodiffusion. PMID- 4298257 TI - Electron microscopic and bioassay studies of milk from mice of high and low mammary-cancer and high and low leukemia strains. PMID- 4298258 TI - The effects of some anti-oestrogens on the deciduoma reaction and delayed implantation in the mouse. PMID- 4298260 TI - Single versus multiple dose dactinomycin therapy of Wilms's tumor. A controlled co-operative study conducted by the Children's Cancer Study Group A (formerly Acute Leukemia Co-operative Chemotherapy Group A). PMID- 4298259 TI - Intermittent steroid therapy. Its effect on hypothalamic-pituitary-adrenal function and the response of plasma growth hormone and insulin to stimulation. PMID- 4298261 TI - The hypothalamic-pituitary axis. PMID- 4298262 TI - Prevention of metastases. PMID- 4298263 TI - The fine structure of an intraoral granular-cell myoblastoma. PMID- 4298264 TI - [Interrelationship between polyoma virus and L cells]. PMID- 4298265 TI - (Na+K+)-activated ATPase in kidney cell membranes of normal and methyprednisolone treated rats. PMID- 4298266 TI - The presence of K+dependent phophatase in intestinal epithelial cell brush borders isolated by a new method. PMID- 4298268 TI - Effects of ATP and Na+ on a K+-activated phosphatase from red blood cell membranes. PMID- 4298267 TI - Stimulatory effect of Na+ and ATP on the release of acetylcholine from synaptic vesicles. PMID- 4298269 TI - Physical state of cytochrome oxidase. Relationship between membrane formation and ionic strength. PMID- 4298270 TI - Inhibition of partial reactions in bacterial photosynthesis by 3-(3,4 dichlorophenyl)-i, i-dimethylurea. PMID- 4298271 TI - The role of ammonium sulfate precipitation in the removal of substances which interfere with enzymatic hydrolysis of conjugated estrogens in pregnancy urine. PMID- 4298272 TI - Visible, optical rotatory dispersion, and paramagnetic resonance spectra of the L histidine--cu(II)--L-threonine complex. PMID- 4298273 TI - [Fibrous osteodysplasia of the temporal bone]. PMID- 4298274 TI - [Contributions to the study of the relationships between the pituitary gland and the adrenal glands in healthy infants]. PMID- 4298275 TI - [Hepatitis in an infant with positive isolation of the cytomegalovirus]. PMID- 4298276 TI - [Electron spin resonance studies of the frozen animal tissues]. PMID- 4298277 TI - [Synthesis of uridine-5'-monophosphoric acid (UMP) in bone marrow of chicks, infected with myeloblastosic virus]. PMID- 4298278 TI - [The significance of the hydrogen index for the effect of imidazole and its derivatives on myoneural transmission of stimulation]. PMID- 4298279 TI - [On the participation of the hypophyseal adrenocorticotropic hormone in adrenaline secretion by the adrenal glands]. PMID- 4298280 TI - [Glucocorticoid activity in adrenal cortex of rats after thermal trauma]. PMID- 4298281 TI - The purification and properties of guanosine diphosphate glucose pyrophosphorylase of pea seedlings. PMID- 4298283 TI - [Adrenal cortex insufficiency and kidney failure]. PMID- 4298282 TI - [Behavior of the epidermis over the histiocytomas in acute psoriatic onset (with observations on the structure of histiocytomas, especially on the behaviot of mast cells)]. PMID- 4298284 TI - [Difficulties in the diagnosis of cerebellar tumors]. PMID- 4298285 TI - [Introspective study of the treatment of peripheral palsy of the upper extremity]. PMID- 4298286 TI - [A case of glomus tumor--chemodectoma--of the larynx]. PMID- 4298287 TI - [Clinical contribution on the diagnosis and therapy of diseases of the submaxillary salivary gland]. PMID- 4298288 TI - [Multiple salivary gland tumors]. PMID- 4298289 TI - Endocrine disorders of the pancreas. PMID- 4298290 TI - [Gout and myxedema]. PMID- 4298291 TI - [Lupoid syndromes after absorption of isoniazid. Study of 6 cases]. PMID- 4298292 TI - [Pathogenesis of necrosis of the femoral head in adults]. PMID- 4298293 TI - [Synovectomy in the treatment of inflammatory rheumatism]. PMID- 4298294 TI - [Atypical psychotic tuberculosis]. PMID- 4298295 TI - [On a case of hypersomnolence with disorders of alimentary behavior, sexual excitation and behavior disorders]. PMID- 4298296 TI - [Physical and physiopathological basis of pulmonary scintillography]. PMID- 4298297 TI - [Indications and results of pulmonary scintillography with the scintillation camera]. PMID- 4298298 TI - [Exogenous diffuse pulmonary granuloma]. PMID- 4298299 TI - [Medico-surgical problems posed by suppurations from the convexity of the right lobe of the liver]. PMID- 4298301 TI - [Lymphography of the chyliferous intestines]. PMID- 4298300 TI - [The brushing technic of endobronchial diagnosis]. PMID- 4298302 TI - [Congenital malformations associated with stenosis of the portal vein]. PMID- 4298303 TI - [Apropos of 4l cases of pilonidal disease with coccy-perineal localization]. PMID- 4298304 TI - [Methandrostenolone, growth and puberty in young girls]. PMID- 4298305 TI - [Evidence of hypersensitivity of the bronchial muscaluture of asthmatics]. PMID- 4298306 TI - [Remarks on contraception]. PMID- 4298307 TI - Influence of pyrophosphate on the crystallisation of uric acid and magnesium ammonium phosphate and its implications in phosphate therapy for urolithiasis. PMID- 4298308 TI - [Change in the bioelectric activity of the brain in young children during ftorotan (fluothane) anesthesia]. PMID- 4298309 TI - [Transsternal phlebography in breast cancer]. PMID- 4298311 TI - [Animal experiment contribution on the problem of increased resistance to a virus infection by physical training (infection with foot-and-mouth disease (FMD) virus of mice trained to swim)]. PMID- 4298310 TI - [Are the speridions in the cell nuclei of diseased tissue of pathognomonic significance?]. PMID- 4298313 TI - Serological data on the distribution of some enteroviruses in Bulgaria. PMID- 4298312 TI - [Antigens of connective tissue. II. Demonstration and trials of the chemical characterization of non-collagenous connective tissue antigens]. PMID- 4298314 TI - [The protective action of cell walls and cytoplasm of Bordetella pertussis]. PMID- 4298315 TI - [Studies on the blood flow of the human kidney following operations on the abdomen]. PMID- 4298316 TI - [Study of various metabolic processes of heart failure in experiments. XI. Involvement of the adrenocortical mechanism in progressive aortic constriction and after the administration of diphtheria toxins observed in radiologic, electrocardiographic and metabolic changes in the myocardium]. PMID- 4298317 TI - [On the role of enteric viruses in the pathology of the nervous system]. PMID- 4298318 TI - [Cylindroma (adenocystic carcinoma) of the salivary glands]. PMID- 4298319 TI - [Simultaneous occurence of a congenital defect of the hand and congenital hyperplasia of the foot. A contribution to W. Muller's malformation therapy of oscillatory variation towards a normal condition]. PMID- 4298320 TI - Electron microscopy of hepatic cell lesions induced by electrocution. PMID- 4298321 TI - [Split-or full thickness skin grafts in surgical treatment of syndactylia]. PMID- 4298323 TI - [Synaptic ultrastructures in the epiphysis of the Chelonia. Presence of synaptic bands at the level of articulations between pseudosensory cells and nerve terminals in the epiphysis of Pseudemys scripta elegans and Pseudemys picta]. PMID- 4298322 TI - Electron-spin-resonance evidence for interaction of protons with Mo(V) in reduced forms of xanthine oxidase. PMID- 4298324 TI - [Study of the mechanism of the induction in Syrian hamster cells transformed by the SV 40 virus: action of temperature on the formation of heterokaryons]. PMID- 4298325 TI - [Characteristics of cultures of 1st explantation of cells of papilloma induced by the Shope virus in the domestic rabbit]. PMID- 4298326 TI - [Pleomorphic sialoadenomas in the soft palate]. PMID- 4298327 TI - Newer antiviral agents--comparative assays in vivo and in vitro. PMID- 4298328 TI - [Lactate dehydrogenase in the cerebrospinal fluid of children. Optimal substrate and coenzyme concentrations, normal values]. PMID- 4298329 TI - Further studies on the oxidation of extramitochondrial reduced nicotineamide adenine dinucleotide in Landschuetz ascites tumor cells. PMID- 4298330 TI - [Fundamentals and development of chemotherapy for bacterial infections]. PMID- 4298332 TI - Studies on the chemical isomerization of vitamin D. IV. Identification of vitamin D2 and its related compounds by thin layer chromatography. PMID- 4298333 TI - [Autopsy case of malignant synovioma]. PMID- 4298331 TI - [Action mechanism of antibacterial and antifungal drugs]. PMID- 4298334 TI - Glycolipids of hamster fibroblasts and derived malignant-transformed cell lines. PMID- 4298336 TI - [Incidence of acute diseases of the respiratory tract in students of the city of Jassy in the period 1961-1966]. PMID- 4298337 TI - [Research on the physiological variations of plasma angiotensin]. PMID- 4298335 TI - A human interferon that crosses the species line. PMID- 4298339 TI - [Electromyography as a neurological aid]. PMID- 4298338 TI - [On the relationship between negative effects and positive effects of ACTH therapy in myasthenic patients]. PMID- 4298340 TI - The effect of lincomycin on neuromuscular transmission. PMID- 4298341 TI - [Removal of a carotid body tumor with transsection and suturing of both branches of the carotid artery]. PMID- 4298342 TI - [Hypoglycemic syndrome in islet cell tumor of the pancreas]. PMID- 4298343 TI - ["Steroid" pancreatitis (review of the literature)]. PMID- 4298344 TI - [Remote sequelae of tetanus]. PMID- 4298345 TI - Hemopexin of rabbits. PMID- 4298346 TI - [Neurophysiological and biochemical regulatory mechanisms of wakefulness function]. PMID- 4298347 TI - [Recommendations of the workshop group "Female Genital Tuberculosis" on the diagnosis therapy and metaphylaxis of tuberculous diseases of the female genitalia]. PMID- 4298348 TI - [Studies of metabolic processes during a drug enhanced choleresis in rats]. PMID- 4298349 TI - [Ultrastructural characteristics of differentiation of primary bronchial cancers. II. The bronchial cylindromas]. PMID- 4298350 TI - [Evaluation of the secretory power of the testes (Recent works)]. PMID- 4298351 TI - [Fatigue and endocrine glands]. PMID- 4298352 TI - [Non-tumoral hirsutism. Pathogenesis and therapeutic trials]. PMID- 4298353 TI - [Plasma level of ACTH in the course of Cushing's syndrome]. PMID- 4298354 TI - [Hypopituitarism of hypothalamic origin]. PMID- 4298355 TI - [Electroencephalography and tumor in the acute phase. B. The EEG in the initial stage of space requiring cerebral processes. Morphological part]. PMID- 4298356 TI - [Electroencephalometric examinations]. PMID- 4298357 TI - [Clinical observations]. PMID- 4298358 TI - [The electroencephalogram in the early phase of hemispheral tumors]. PMID- 4298359 TI - [Electroencephalography and tumor in the acute phase. D. Conclusions]. PMID- 4298361 TI - [A study of the structure of paramagnetic centers in monocrystals of gamma irradiated L-cystine dihydrochloride under the effect of light]. PMID- 4298360 TI - [Phototransformation of porphyrins in frozen solutions. Oxidative medium]. PMID- 4298362 TI - [Optical properties of biopolymers in the field of electron absorption bands]. PMID- 4298363 TI - [The effect of lyophilization on the ESR spectrum of animal tissue]. PMID- 4298364 TI - [Changes in the antioxidative activity of liver and tumor lipids in the process of development of Zeidel's ascitic hepatoma and its treatment with antineoplastic agents]. PMID- 4298365 TI - [Detection of myeloblastosis virus antigen in cell cultures]. PMID- 4298366 TI - [Electronic representation of ion exchanges through the membrane of the neuron: diffusion of the depolarization wave]. PMID- 4298367 TI - [Histochemichal enzyme studies in Candida albicans]. PMID- 4298368 TI - [Determination of body length and age of human fetus on the basis of bone measurements of the skull basis]. PMID- 4298369 TI - [Determination of body length and age of human fetuses on the basis of gross size of the facial bones]. PMID- 4298370 TI - [Determination of body length and age of human fetuses on the basis of first hand and first foot root bone measurement, as well as the size of the atlas and epistropheus vertebral arch]. PMID- 4298371 TI - [Effects of adenosine 3',5'-cyclic monophosphate (cyclic AMP) on the circulatory system and renal function]. PMID- 4298372 TI - [Influencing of lung function using lymphography with oily contrast medium]. PMID- 4298373 TI - [On the "so-called adamantinoma" of the long bones. Singular observations as a contribution to differential diagnosis]. PMID- 4298374 TI - [On the etiology of pertussis encephalosis]. PMID- 4298375 TI - [The importance of angiography in the treatment of islet cell tumors]. PMID- 4298376 TI - [Treatment with conjugated estrogens]. PMID- 4298377 TI - [Necrobiosis lipoidica diabeticorum (Oppenheim-Urbach)]. PMID- 4298378 TI - [On the effect of quartz on lysosomes in vitro]. PMID- 4298379 TI - [Growth of transplanted tumors in rats with alloxan diabetes]. PMID- 4298380 TI - Changes in phosphate content associated with "green ear" disease of Bajra. PMID- 4298381 TI - [Disturbances of carbohydrate metabolism in potassium deficiency]. PMID- 4298382 TI - Acute viral respiratory infections in Switzerland 1967. PMID- 4298383 TI - [Clinical contribution on the differential diagnosis of peripheral facial diplegia]. PMID- 4298384 TI - [The classification of the virus]. PMID- 4298385 TI - [The neurosurgical treatment of pain]. PMID- 4298386 TI - [Glucose-6-phosphate dehydrogenase in the clinic: enzymatic deficit and qualitative variations]. PMID- 4298387 TI - [Hemostasis in obstetrics. 10 years of experience. New facts on thromboplastin formation]. PMID- 4298388 TI - [The effects of motor activity in a case of maduromycosis of the foot. Clinical, biologic and radiologic aspects after 17 years of development]. PMID- 4298389 TI - [Contribution to the pathogenesis of herpes corneae simplex]. PMID- 4298390 TI - [Problems of rehabilitation in coronary disease from the view pointa of the ambulatory heart specialist]. PMID- 4298392 TI - [The technic of the "cigarette plastic surgery" for the commissure formation in the partition of syndactylia]. PMID- 4298391 TI - [The disease picture of acute toxic epidermolsis in children caused by drug intolerance. Report on 4 personal cases]. PMID- 4298393 TI - [Synovitis villosa pigmentosa: diagnosis and differential diagnosis]. PMID- 4298394 TI - [On the clinical diagnosis of malignant synoviomas]. PMID- 4298395 TI - Esophageal varices in the absence of cirrhosis, Incidence and characteristics in congestive heart failure and neoplasm of the liver. PMID- 4298396 TI - Vaccination of beef calves before weaning with a live-virus bovine myxovirus parainfluenza-3 vaccine. PMID- 4298397 TI - Attempts to relate bovine papilloma virus to the cause of equine sarcoid: immunity to bovine papilloma virus. PMID- 4298398 TI - pH resistance of foot-and-mouth disease virus and its complement-fixing antigen. PMID- 4298400 TI - Studies on Chikungunva virus. 3. Infective ribonucleic acid from partially purified virus: its biological assay and some of its basic characteristics. PMID- 4298399 TI - Endocrine relations between mother and fetus. PMID- 4298402 TI - Peripheral brachial neuropathy secondary to lightning shock with recurrent fractures of the 5th metacarpal bone. Case report. PMID- 4298401 TI - Studies on lysosomes. IX. Localization of bacteriophages and thorotrast and their inflammatory properties. PMID- 4298403 TI - Conservative (supportive) treatment of severe ulcerative colitis. Methods and results. PMID- 4298404 TI - Modification of the transfer function of proline transfer ribonucleic acid synthetase by temperature. PMID- 4298405 TI - Separation and detection of biogenic amines by thin-layer chromatography. Micro analysis of tissue amines and of enzymes involved in their metabolism. PMID- 4298406 TI - Peroral infection and resistance to reinfection with encephalomyocarditis virus in the mouse. PMID- 4298407 TI - Virologic aspects in studies of Japanese and tick-borne encephalitis. PMID- 4298408 TI - Correlation between clinical pattern and pathological findings in Cushing's syndrome. PMID- 4298409 TI - The dynamic behaviour of proteins during catalysis. PMID- 4298410 TI - [Protuberances on the cell surface of Escherichia coli B following action of polymyxin B]. PMID- 4298411 TI - Current concepts of burn injury. II. PMID- 4298412 TI - The anterior and posterior meningeal branches of the vertebral artery. PMID- 4298413 TI - Considerations on the permanence of psychiatric rehabilitation. PMID- 4298414 TI - Facilitated proton transfer in enzyme catalysis. It may have a crucial role in determining the efficiency and specificity of enzymes. PMID- 4298415 TI - [On so-called familial acroosteolysis with nervous system disease]. PMID- 4298416 TI - [The fatty acid composition of individual lipid fractions of fetal and maternal rat liver as well as of the placenta and its changes at the end of pregnancy]. PMID- 4298417 TI - [Localization and organization of ribosomes in liver and hepatoma tissues]. PMID- 4298419 TI - [Glucoactive adrenocortical function in the aged. Plasma and urinary steroids under basal conditions. ACTH stimulation test, and inhibition tests using 6 methylprednisolone and dexamethasone]. PMID- 4298418 TI - [Clinical and biological study of an inhibitor of adrenocortical hormone synthesis: aminoglutethinide]. PMID- 4298420 TI - [Cushing's syndrome caused by a malignant thymus tumor secreting corticotropin]. PMID- 4298421 TI - Comparative pathogenicity of vesicular stomatitis virus and its plaque type mutants. PMID- 4298422 TI - Improved techniques for the detection of foot-and-mouth disease virus in carrier cattle. PMID- 4298423 TI - The experimental production of a formalin-killed Japanese encephalitis virus vaccine from porcine kidney cell cultures. PMID- 4298424 TI - Histopathological and virological studies on monkeypox. PMID- 4298427 TI - [Studies on the nucleic acid metabolism of monkey kidney tissue culture cells after infection with SV40. 3. Studies on the mechanism of virus-directed DNA synthesis increases]. PMID- 4298425 TI - [Masked genome in foot-and-mouth disease virus and the behavior of the masked genome virus in thermal inactivation]. PMID- 4298426 TI - Interaction of interferon with chick embryo cells. PMID- 4298428 TI - [Research on immunity and proteinemia in silicosis. I. Effects of silica on the production of antibodies]. PMID- 4298431 TI - [On various strains of Salmonella typhimurium with multiple resistance to antibiotics, due to R factor]. PMID- 4298430 TI - [Enzymatic aspects of the host cell-virus relation. I. Meaning of the presence of lactate dehydrogenase and of glutamic-oxaloacetic transaminase in cell cultures infected with cytopathogenic viruses of DNA and RNA type]. PMID- 4298429 TI - [Research on immunity and proteinemia in silicosis. II. Effects of silica on anaphylaxis]. PMID- 4298433 TI - Effects of piercidin A on the metabolism of isolated adipose cells. PMID- 4298432 TI - Inhibition of biliary secretion by icterogenin and related triterpenes. I. Effect of icterogenin, rehmannic acid and oleanolic acetate on liver mitochondria in vitro. PMID- 4298434 TI - Study on the effect of 3-acetylpyridine on blood glucose concentration. PMID- 4298435 TI - Site of foot-and-mouth disease virus-ribonucleic acid synthesis and some properties of its double-stranded ribonucleic acid. PMID- 4298436 TI - Difference in binding of 2-acetylaminofluorene to rat liver deoxyribonucleic acid and ribosomal ribonucleic acid in vivo. PMID- 4298437 TI - [The effect of penicillin and some semisynthetic penicillins on the respiratory chain enzymes of Staphylococcus aureus 209-P]. PMID- 4298438 TI - [The biosynthesis of nicotinamide mononucleonucleotide in heart muscle]. PMID- 4298439 TI - [Hydrolysis of seryl pyrophosphates by inorganic pyrophosphatase of yeast]. PMID- 4298440 TI - [EMR identification of ferro-cysteine complexes in biological systems]. PMID- 4298442 TI - [Study of acid soluble phosphate compounds from Clostridium perfringens]. PMID- 4298441 TI - [Synthesis of adrenocorticotropic-like substance in Escherichia coli cell-free system induced by informational RNA from bovine adenopituitary glands]. PMID- 4298444 TI - [Biological determination of intermedine in hypophysis and placenta of human embryos]. PMID- 4298443 TI - [On the mechanism of ubiquinone functioning in mitochondrial respiratory chain]. PMID- 4298445 TI - [A note concerning fractional centrifugation of rat liver]. PMID- 4298447 TI - [Radiology of Paget's disease of the breast]. PMID- 4298448 TI - [Some problems of radiodiagnosis of non-palpable neoplasms of the breast]. PMID- 4298446 TI - A 'short1 feedback mechanism controlling FSH secretion. PMID- 4298449 TI - [Breast sarcomas]. PMID- 4298450 TI - [Glandular epithelioma of the breast: metastases in the homolateral brachial plexus?]. PMID- 4298451 TI - [Effect of angiotensin on sodium and urine excretion in dogs in conditions of unilateral, acute renal artery stenosis]. PMID- 4298453 TI - Hydrogen addition radicals of stilbestrol, hexestrol, and benzestrol. PMID- 4298452 TI - [Research on the physiological properties and protein composition of renal extracts with renin activity from various animal species]. PMID- 4298454 TI - [Effect of perchlorate on the thyroid gland of euthyroid persons]. PMID- 4298455 TI - [Indication establishment and dosimetry in endolymphatic therapy with I-131 lipiodol]. PMID- 4298457 TI - [The value f various loading tests in the diagnosis of insuloma]. PMID- 4298456 TI - [On a functional examination of the adrenal cortex for the purpose of radiotherapy]. PMID- 4298459 TI - [Virus isolation from patients with infectious hepatitis]. PMID- 4298458 TI - [Contribution to the diagnosis of islet cell tumors]. PMID- 4298460 TI - [Diagnosis and therapy of gastric secretion and motility disorders. (At the same time, a contribution to the study of secretory capability of the gastric mucosa during the action of vasoactive substances]. PMID- 4298461 TI - [What conclusions can be reached from experimental tumor research concerning the relationship between hormones and tumor formation?]. PMID- 4298462 TI - [Clinical features of paraneoplastic endocrinopathies]. PMID- 4298463 TI - [Pathology of ectopically hormone-producing tumors]. PMID- 4298464 TI - [Experiences with the angiotensin infusion test according to Kaplan and Silah in the diagnosis of hypertension]. PMID- 4298465 TI - [On the rhythm of secretion of hormones from the human adrenal cortex during several days of observation]. PMID- 4298466 TI - [The effect of lithium chloride on the blood pressure action of renin, angiotensin and noradrenaline in rats]. PMID- 4298467 TI - [Experimental results of chronopharmacology of corticosteroids]. PMID- 4298468 TI - [Mass cells and lipid metabolism]. PMID- 4298469 TI - [On secondary brain stem symptoms in tumors of the base of the brain]. PMID- 4298470 TI - Studies on the histochemical distribution of oxidative enzymes in sympathetic ganglion cells of rat. PMID- 4298472 TI - Histochemical localization of ACTH and TSH in the human hypophysis. PMID- 4298471 TI - [Histologic-histochemical studies on the effect of ACTH on the isolated adrenal gland of juvenile mice and adult frogs]. PMID- 4298473 TI - Studies on the histochemical distribution of phosphatases in sympathetic ganglion neurons of rat. PMID- 4298474 TI - [Content of some phosphatases in the testicles of the rat, mouse and guinea pig after estrogen treatment]. PMID- 4298475 TI - [Thiazol blue dyes in histochemistry. Indirect demonstration of cytochrome oxidase]. PMID- 4298477 TI - Preparation of cytomegalovirus immune serum in rabbits with alkaline-extracted virus. PMID- 4298476 TI - The thymus of the adult stressed dog, a predominantly epithelial organ. A histological, histochemical and statistical study. PMID- 4298478 TI - Natural history of Sendai virus infection in mice. PMID- 4298479 TI - Characteristics of vaccine-induced and natural infection with adenovirus type 4 in naval recruits. PMID- 4298480 TI - A community study of respiratory infections in the tropics. II. The spread of six rhinovirus isolates within the community. PMID- 4298481 TI - A community study of respiratory infections in the tropics. 3. Introduction and transmission of infections within families. PMID- 4298482 TI - The role of a neighborhood service center in community mental health. PMID- 4298483 TI - Electron microscopic studies of capillaries in experimental chronic granulomas. PMID- 4298484 TI - A case of ovarian arrhenoblastoma. PMID- 4298486 TI - [Apropos of 16 cerebral tumors observed over 10 years among the entrants to a women's department]. PMID- 4298485 TI - [Chemical and immunologic relationships in the Actinomycetales. IV. Chemical composition of the lipids of 4 strains of Streptomyces and 1 strain of N. (Str.) gardneri]. PMID- 4298487 TI - Synthesis, biological activity., and metabolism of 22,23-3H vitamin D4. PMID- 4298488 TI - Investigation of the component reactions of steroldemethylation: preparation and properties of yeast demethylase activity. PMID- 4298489 TI - Inhibition and release of respiration in particles from Alcaligenes faecalis. PMID- 4298490 TI - Thyroid hormone action on mitochondria. II. Effect of dinitrophenol. PMID- 4298491 TI - Transference of triplet state excitation energy from tyrosine to tryptophan. I. Amino acids in simple and mixed solutions. PMID- 4298492 TI - Studies on chemical mechanisms of the action of neurotransmitters and hormones. I. Relationship between hormone stimulated 32P incorporation into phosphatidic acid and into phosphatidylinositol in pigeon pancreas slices. PMID- 4298493 TI - Studies on chemical mechanisms of the action of neurotransmitters and hormones. II. Increased incorporation of 32P into phosphatides as a second, adaptive response to pancreozymin or acetylcholine in pigeon pancreas slices. PMID- 4298494 TI - Curdlan: a bacterial gel-forming beta-1,3-glucan. PMID- 4298495 TI - L-O-Methylthreonine--synthesis and mode of action as an isoleucine antagonist. PMID- 4298496 TI - Subcellular distributions and properties of rat liver phosphodiesterases. PMID- 4298497 TI - The mechanism of liver alcohol dehydrogenase. PMID- 4298498 TI - Investigations on the biogenesis of chlorophyll a. I. Purification and mass spectra of maleimides from the oxidation of chlorophyll and related compounds. PMID- 4298499 TI - Reduction of hydroxylamine by rat liver mitochondria. PMID- 4298500 TI - [Muco-epidermoid carcinoma of the palate. (Observations on a 14-years-old patient)]. PMID- 4298501 TI - Glomus tumor of the stomach. Report of a case. PMID- 4298502 TI - [On the phosphate turnover of phosphatides of tumor cells in culture]. PMID- 4298504 TI - Neurology of depression. PMID- 4298503 TI - Effects of avenaciolide on lipolysis and on glucose, amino acid and palmitic acid metabolism in isolated adipose cells. PMID- 4298505 TI - The chronic patient in the community. A two-year follow up of 338 chronic patients. PMID- 4298506 TI - The mental health services in the Soviet Union. PMID- 4298507 TI - [Infectious diseases and pregnancy]. PMID- 4298508 TI - [Is the subacute progressive panencephalitis a measle disease? A contribution to the clinical picture, morphology and etiology]. PMID- 4298510 TI - [The Sanarelli-Shwartzman phenomenon in the light of modern research. 3]. PMID- 4298509 TI - [Studies on the angiotensin-aldosterone system in sodium-loaded rats]. PMID- 4298511 TI - [Angiotensin resistance and hyperaldosteroniam with normal blood pressure]. PMID- 4298513 TI - Studies of aldehyde oxidase by electron paramagnetic resonance spectroscopy. II. Kinetic studies by rapid freezing. PMID- 4298512 TI - Studies of aldehyde oxidase by electron paramagnetic resonance spectroscopy. I. Spectra at equilibrium states. PMID- 4298514 TI - Biosynthesis of long chain fatty acids by subcellular particles of mature brain. PMID- 4298515 TI - Controle of the metabolism and lipolytic effects of cyclic 3',5'-adenosine monophosphate in adipose tissue by insulin, methyl xanthines, and nicotinic acid. PMID- 4298516 TI - Vitamin D-dependent calcium-binding protein. Purification and some properties. PMID- 4298517 TI - Vitamin D-dependent calcium-binding protein. Response to some physiological and nutritional variables. PMID- 4298518 TI - Studies on cytochrome c peroxidase. XI. A crystalline enzyme reconstituted from apoenzyme and manganese protoporphyrin IX. PMID- 4298519 TI - Class separation of flavour volatiles by liquid chromatography on silica gel at 1 degree. PMID- 4298520 TI - Control of bleeding during surgery on vascular tumors of the head. PMID- 4298521 TI - [Studies on bovine enteroviruses. 1. Isolation and properties]. PMID- 4298522 TI - [Studies on bovine enteroviruses. II. Serial passages and growth curves in various cell cultures]. PMID- 4298523 TI - [Studies on bovine enteroviruses. 3. Hemagglutination]. PMID- 4298524 TI - [Studies on bovine enteroviruses. IV. Neutralizing antibodies in the Kyushu district]. PMID- 4298525 TI - [The modification of experimental exophthalmos in animals by various hormones]. PMID- 4298527 TI - [Studies on the plasma amino acid changes during the insulin-stress test in man]. PMID- 4298528 TI - [Corticoid therapy from the surgical viewpoint of abdominal complications]. PMID- 4298526 TI - [Virus-induced fever. (Results and problems)]. PMID- 4298529 TI - The binding of noradrenaline to monophosphoinositide: in vitro studies. PMID- 4298530 TI - [Apropos of an experience with the polychemotherapy of cancer]. PMID- 4298531 TI - [Methylated bases in t-RNA of cerebral tumors]. PMID- 4298532 TI - [The intraductal carcinoma of the breast is never a carcinoma in situ]. PMID- 4298533 TI - [Malignant granular cell myoblastomyoma]. PMID- 4298535 TI - [So-called benign mixed tumors of submandibular salivary gland; report of two cases]. PMID- 4298534 TI - Ultrastructure of a so-called granular cell myoblastoma. PMID- 4298536 TI - A skeleton which was not considered as a criminal case. PMID- 4298537 TI - [Late results of prosthetic treatment in 2 cases of hereditary odontogenesis imperfecta]. PMID- 4298538 TI - Type II syndactyly. PMID- 4298539 TI - Evaluation of deficiency of 21-hydroxylation in patients with congenital adrenal hyperplasia. PMID- 4298540 TI - Planography during pneumoencephalography. The diagnosis of lesions affecting the optic pathways. PMID- 4298541 TI - Clear cell hidradenoma of the eyelid. PMID- 4298542 TI - The chronology of primary herpes simplex infection of the eye and adnexal glands. PMID- 4298543 TI - [Collet-Sicard syndrome]. PMID- 4298545 TI - Ultrastructural studies on nucleic acids of nucleolar granular components in Novikoff hepatoma cells. PMID- 4298546 TI - [Clinical and serological data on adenovirus infections observed in Puglia]. PMID- 4298547 TI - [Study of the action of potassium atractylate (Atractyloside) on experimental infection with MHV-3 virus]. PMID- 4298548 TI - [Report of the activity of the virology laboratory of the Clinica Medica de Bari in the 15-year period of 1960-1964]. PMID- 4298544 TI - Histamine-sensitizing factors from microbial agents, with special reference to Bordetella pertussis. PMID- 4298549 TI - Immunosuppressive effects of macrophage antiserum. PMID- 4298550 TI - Studies on serum complement lvel in rabbits bearing tumours of Shope papilloma carcinoma complex. PMID- 4298551 TI - Detection of antigens of a new diethylnitrosamine-induced transplantable hepatoma by delayed hypersensitivity. PMID- 4298552 TI - Observations on the nature of a genetic cellular resistance to avian tumor viruses. PMID- 4298553 TI - Antigenicity of a new diethylnitrosamine-induced transplantable guinea pig hepatoma: pathology and formation of ascites variant. PMID- 4298555 TI - Infection of the vulva and cervix with a genital strain of herpes simplex virus. PMID- 4298554 TI - Acute necrotizing haemorrhagic encephalitis presenting clinically as a space occupying lesion. A clinico-pathological study of six cases. PMID- 4298556 TI - Cytomegalic inclusion-body disease. PMID- 4298559 TI - Interactions between chlorophyll and water in the solid state: electron spin resonance. PMID- 4298558 TI - [On an unusual case of metastatic vertebral cylindroma]. PMID- 4298557 TI - [Current trends in the prevention and treatment of severe accidents of intolerance to iodized contrast media]. PMID- 4298560 TI - Agglutinating antibodies in the sera of chickens with regressing Rous sarcomas. PMID- 4298561 TI - Rhabodomyosarcoma simulating nasopharyngeal angiofibroma. PMID- 4298562 TI - [Distribution of intracellular ADP, ATP and orthophosphate in the resting and tetanically stimulated frog musculature by means of a fractionated extraction]. PMID- 4298563 TI - Transformation of animal cells by oncogenic DNA viruses. PMID- 4298564 TI - [Considerations on a case of Krukenberg's syndrome]. PMID- 4298565 TI - [Toxin production by Cl. perfringens of types A and D on synthetic media]. PMID- 4298566 TI - [Nitrosohemoglobinemia in nitrite poisoning]. PMID- 4298567 TI - [Experimental-clinical study of endogenous and exogenous interferons]. PMID- 4298568 TI - [Experimental-clinical study of combined use of antibiotics and prodigiozan]. PMID- 4298570 TI - [On the suitability of 2 isologous tumor-host systems for chemotherapeutic studies]. PMID- 4298569 TI - [Achievements of Soviet selection of strains--producers of antibiotics]. PMID- 4298571 TI - [On the problem of malignant gliomas of the brain. I]. PMID- 4298572 TI - Effects of reserpine, furosemide and hydrochlorothiazid on modifications of the pressure response to bradykinin and angiotensin provoked in the rat by guanethidine. PMID- 4298574 TI - [Polarographic evaluation of magnesium silicate thin layer chromatograms]. PMID- 4298573 TI - [Some studies on the enzymatic synthesis of glucosamine-6-phosphate in rat liver homogenates and their modification in vivo]. PMID- 4298576 TI - [Metastasizing retroperitoneal chemodectoma (nonchromaffin paraganglioma)]. PMID- 4298575 TI - [Indications for lymphography in malignant tumors of the urogenital tract]. PMID- 4298577 TI - [On the angiographic demonstration of glomus tumors]. PMID- 4298578 TI - [Lymphogram with contrast media conversion in the colon in metastasis-dependent, retroperitoneal lymphatic block]. PMID- 4298579 TI - [Inhibition of lactate dehydrogenase by adenosine phosphate]. PMID- 4298580 TI - [Changes in concentration of effectors of key gluconegenesis enzymes in rat liver under gluconeogenetic conditions]. PMID- 4298581 TI - [Enzymes of fructose metabolism. Activity and distribution in the rat liver]. PMID- 4298582 TI - [On the degradation of sorbitol by bacteria from rat feces]. PMID- 4298583 TI - [Specificity and localization of the effect of estrogens on electron transport]. PMID- 4298584 TI - [Japanese B encephalitis and immunity]. PMID- 4298585 TI - [Dysplastic developmental disorders in the cranio-facial region with malformations of the extremities]. PMID- 4298588 TI - [Virus-induces intestinal infections]. PMID- 4298587 TI - [The effect of noradrenalin and angiotensin on kidney function and plasma renin level in a patient with secondary aldosteronism and arterial hypotension]. PMID- 4298589 TI - The interaction between angiotensin and sympathetically-induced vasoconstriction in the isolated perfused central ear artery of the rabbit. PMID- 4298586 TI - [Studies on the pattern and distribution of enzymes in human gastrointestinal mucosa. II. Histochemical and supplementary isoenzyme studies. II]. PMID- 4298590 TI - A comparison of the concentrations of steroids in the adrenal gland with the rates of their secretion. PMID- 4298591 TI - The conversion of angiotensin I to angiotensin II in vivo. PMID- 4298593 TI - Intercalation into DNA. PMID- 4298592 TI - Evidence against the participation of acetylcholine in transmission at sympathetic adrenergic nerve terminals. PMID- 4298594 TI - [Biological role of copper compounds]. PMID- 4298595 TI - [Contribution to the knowledge of the origin of the adrenocorticotropic hormone]. PMID- 4298597 TI - Interactions of L-glutamic acid, gamma-aminobutyric acid and Pyridoxal-5' phosphate at ehe neuronal level. PMID- 4298596 TI - [Use of electronic paramagnetic resonance for detection of free radicals in fatty acids]. PMID- 4298599 TI - [Surgery of progressive cancer. Pancreatic cancer and cholangioma]. PMID- 4298598 TI - [Pituitary syndromes of diencephalic origin. Clinical application of pituitary stimulation tests]. PMID- 4298600 TI - [Evaluation of the effect of Longmire-Sanford surgery of cholangioma]. PMID- 4298601 TI - [Synthesis of glucuronic acid "in vitro" and "in vivo" after whole body irradiation in rats]. PMID- 4298602 TI - Changes in circulating lymphocytes induced by the administration of ACTH in cocks. PMID- 4298603 TI - [Effect of some antibiotics on the transfer of the resistance to tetracycline and chloramphenicol by means of the episome factor (Rtf)]. PMID- 4298604 TI - [Clinico-morphological characteristics of the liver in experimental dysentery, treated by chlortetracycline in combination with ACTH and cortisone]. PMID- 4298606 TI - [On the problems of malignant degeneration of gliomas of the cerebrum (II)]. PMID- 4298605 TI - [Study of the sensitivity of polyresistant strains of microbial causative agents of purulent infections to kanamycin sulfate]. PMID- 4298607 TI - [Autoradiographic, immunofluorescence and morphological studies on the distribution and effect of o-aminoazotoluene (OAAT)in the mouse liver]. PMID- 4298608 TI - [On the mechanism of electron transport in the oxidation-reduction chain in experimental myocardial infarct]. PMID- 4298609 TI - [Qualitative identification of particular fractions of brain phospholipids employing infrared spectroscopy]. PMID- 4298610 TI - [Participation of serine and histidine in formation of purine bases of nucleotides and nucleic acids in hepatoma]. PMID- 4298611 TI - [Substrate effect on heat inactivation of NADH oxidase and its fractions]. PMID- 4298612 TI - [Some features of solubilazation of enzymes from lysosomes and sarcoplasmic reticulum of the rat heart]. PMID- 4298613 TI - [Hypophyseo-adrenocortical function in diseases of the diencephalo-hypophysis and its related regions (with special reference to diurnal rhythm and ACTH test)]. PMID- 4298614 TI - [Clinical experiences with the hemostyptic Presomen]. PMID- 4298615 TI - [Catecholamines]. PMID- 4298616 TI - [2,3-diphosphoglycerate metabolism in the erythrocytes of the newborn and of adults]. PMID- 4298617 TI - [Comparative biochemical studies of erythrocytes from the blood of the newborn and of adults]. PMID- 4298618 TI - [Measles antibodies in the serum of patients with multiple slcerosis]. PMID- 4298619 TI - [Relations between sodium metabolism of the erythrocytes and vascular reactibility in normotensive subjects with a family history of hypertension]. PMID- 4298620 TI - [Multifocal and pluricentral cancerization by oncogenic Polyoma virus]. PMID- 4298621 TI - [On clinical aspects of adrenal cortex insufficiency]. PMID- 4298622 TI - [Atypical EEG findings in brain atrophy]. PMID- 4298623 TI - [On differential diagnosis of labyrinthine and retrolabyrinthine vestibular nerve disorders]. PMID- 4298624 TI - [Extensive sclerosing hemangioma of the paranasal sinuses and its clinical complications]. PMID- 4298625 TI - [Epidemiological studies of common cold diseases. Diagnosis and therapy]. PMID- 4298626 TI - [The West-syndrome and its treatment with ACTH]. PMID- 4298627 TI - [Lymphography]. PMID- 4298628 TI - [Persistent disorders of ACTH secretion following surgery of an adrenal cortex adenoma in 3 cases of Cushing's syndrome]. PMID- 4298629 TI - Liver biopsy in human leptospirosis: a light and electron microscopy study. PMID- 4298630 TI - [The mass density of Herpes simplex virus in a cesium chloride-water gradient. Relations to the plaque morphology on HeLa cells and to the serological type]. PMID- 4298631 TI - [Pathology and clinical picture of alveolar-cell carcinoma appearing as a circular focus]. PMID- 4298632 TI - Antibody formation in cell cultures. 1. Membrane cultures of lymphoid cells: a system for studies of long term secondary antibody responses to poliovirus. PMID- 4298633 TI - [Staphylococci resistant to semisynthetic penicillins, isolated from patients]. PMID- 4298634 TI - [Effect of streptomycin, D-cycloserine, kanamycin and florimycin on the prothrombin time in albino mice and rabbits]. PMID- 4298635 TI - Plasma renin activity and angiotensin pressor dose in hypertension correlation and diagnostic implications. AB - Data obtained from 65 hypertensive patients showed a clear-cut positive correlation between peripheral plasma renin activity and the pressor response to exogenous angiotensin II (r =+0.75). For the various causes of hypertension, the mean values of plasma renin concentration were found to correspond closely to the mean values of the angiotensin pressor dose. In individual cases, however, the pressor dose of angiotensin was not found to be a reliable gauge of peripheral venous renin activity.It was impossible to establish a causal diagnosis from the results of the angiotensin infusion test or the renin level in peripheral blood under normal conditions. If, however, determinations are carried out on the renal venous effluent with sodium restriction and with the patient in the upright position the renin level is very valuable both in the diagnosis of renovascular hypertension and in predicting the probable outcome of surgical treatment. PMID- 4298636 TI - Cancer of the pancreas. PMID- 4298637 TI - [Modern trends in the therapy and prevention of tetanus (with presentation of personal cases in the infantile age)]. PMID- 4298639 TI - The chromosomes of forty-two primary Rous sarcomas of the Chinese hamster. PMID- 4298638 TI - [Considerations on the composition and mechanism of production of white bile in rats poisoned with alpha-naphthyl-isothiocyanate]. PMID- 4298640 TI - Dental silicate cements. VI. Infrared studies. PMID- 4298641 TI - Early external auditory canal tumors. PMID- 4298642 TI - [Study of lipid metabolism in premature and full-term newborn infants, using Silverman's lipiodol test]. PMID- 4298643 TI - Inclusion compounds of cyclodextrins. PMID- 4298644 TI - [Angiomatous tumors]. PMID- 4298645 TI - [Treatment of infections caused by herpes simplex viruses and viruses of the group zoster-varicella in the light of modern views]. PMID- 4298646 TI - [On sodium and potassium metabolism in epidemic hepatitis]. PMID- 4298647 TI - Incorporation of methyl groups by viral and cellular RNA of HEp 2 cells after poliovirus infection. PMID- 4298648 TI - Interferon-stimulating and in vivo antiviral effects of various synthetic anionic polymers. PMID- 4298649 TI - Action of guanidine on the replication of poliovirus RNA. PMID- 4298650 TI - Induction of cellular mRNA synthesis in BSC-1 cells infected by SV40. PMID- 4298651 TI - Isolation and structure of the nucleocapsid of HVJ. PMID- 4298652 TI - Density difference of DNA of human herpes simplex viruses, types I and II. PMID- 4298653 TI - [Diagnostic and therapeutic use of synthetic beta 1-24 corticotropin (30'920-BA Synacthen Ciba)]. PMID- 4298654 TI - [Neurohormonal conditions of the regulation of pigment reactions]. PMID- 4298655 TI - [Cytochemical characteristics of nucleoprotein structure in cells in tissue culture under normal conditions and under the effects of viruses]. PMID- 4298656 TI - Melanocyte-stimulating and corticotrophic activities in human foetal pituitary glands. PMID- 4298658 TI - Hamartoma of the tongue. Report of a case. PMID- 4298657 TI - Vasopressor drugs and catecholamines. PMID- 4298660 TI - Juvenile nasopharyngeal fibroma in female adult. Report of a case. PMID- 4298659 TI - Granular cell schwannoma (myoblastoma). Report of cases. PMID- 4298661 TI - Nicotinamide adenine dinucleotide in the treatment of chronic schizophrenic patients. PMID- 4298662 TI - Bacitracin and polymyxins. PMID- 4298663 TI - Experimental chemotherapy of tuberculosis. PMID- 4298665 TI - Infusion of liver tumours. PMID- 4298664 TI - Renal tumours and hypertension. PMID- 4298666 TI - Herpes encephalitis. PMID- 4298667 TI - [Aldosterone secretion, plasma renin activity and nephrotic syndromes in rats]. PMID- 4298668 TI - [Some histoenzymologic aspects of the mesothelial shealth of the seminal ducts in rats]. PMID- 4298669 TI - [Attempt at analysis of the source of mass respiratory disease in a group of children]. PMID- 4298670 TI - [Degradation of ethanol in the infant organism following intravenous administration]. PMID- 4298671 TI - Glucagon. PMID- 4298672 TI - Adipose tissue dynamics and regulation, revisited. PMID- 4298673 TI - Deterioration of esophageal peristalsis in patients with alcoholic neuropathy. PMID- 4298674 TI - Effect of the intestinal bacterial flora on acute gastric stress ulceration. PMID- 4298675 TI - Diagnosis and management of the megacolon of ulcerative colitis. PMID- 4298676 TI - [Uncommon blood vessel tumors of the skin. Clinical picture, pathological anatomy and histology as well as classification]. PMID- 4298677 TI - [Benign mucosal pemphigoid in otorhinolaryngology]. PMID- 4298678 TI - [Staphylogenous impetigo and impetigo infected artifacts, lupus erythematosus chronicus, Boeck's sarcoidosis, lupus miliaris faciei, eczema herpeticatum, eosinophilic granuloma, acanthosis, nigricans, subungual melanoma]. PMID- 4298679 TI - [Biosynthesis of folic acid- and NAD-analogs]. PMID- 4298680 TI - A study of the effects of remotivation on social competence, social interest and personal neatness. PMID- 4298681 TI - Conflict: the nurse as therapist and researcher. PMID- 4298682 TI - Hong Kong and its millions of refugees. PMID- 4298683 TI - Discharged psychiatric patients' visits to a former treatment center: a nursing dilemma. PMID- 4298685 TI - Lay literature as an adjunctive teaching tool. PMID- 4298684 TI - The student nurse. PMID- 4298686 TI - International trends. WHO in Europe. PMID- 4298687 TI - Speaking out. on: dealing with irresponsible acting-out behavior in these United States. PMID- 4298688 TI - Psychiatric drugs & trends. The "Brand Name" game. PMID- 4298689 TI - [Classification attempt concerning anaerobic spore-forming bacilli based on fermentation types]. PMID- 4298690 TI - [Electrophoresis with application of the magnetic field. I. Studies on enzymes produced by Clostridium perfringens]. PMID- 4298692 TI - [Hiatal hernia and carcinoma of the cardia. Clinical-diagnostic importance]. PMID- 4298691 TI - [Clinical studies on the effect of diethyldioxystilbene diphosphate on the adrenal cortex]. PMID- 4298693 TI - Acute infectious lymphocytosis. An etiologic and epidemiologic study of an outbreak. PMID- 4298694 TI - Effect of glucagon on heart. PMID- 4298695 TI - [A contribution to the knowledge of the dento-olivary pathway. Anatomical study of 2 cases of hypertrophic degeneration of the olivary nucleus following limited softening of the tegmentum mesencephali]. PMID- 4298696 TI - Induction of antibodies to porcine ACTH in rabbits with nonsteroidogenic polymers of BSA and ACTH. PMID- 4298697 TI - Interferon production in cell lines derived from patients with infectious mononucleosis. PMID- 4298698 TI - Phospholipase activity of the delta hemolysin of Staphylococcus aureus. PMID- 4298699 TI - Isolation of human enteroviruses from beagle dogs. PMID- 4298700 TI - Rare earth metals and soft-tissue calcification. PMID- 4298701 TI - Presence of antibodies to simian virus 40 (SV40) T antigen in rhesus monkeys infected experimentally or naturally with SV40. PMID- 4298702 TI - The incidence of complement-fixing antibodies to herpes simplex and herpes-like viruses in man and rhesus monkeys. PMID- 4298704 TI - Criteria for physiological stress produced by increased chronic acceleration. PMID- 4298705 TI - The preparation and characterization of large oligoribonucleotides. PMID- 4298703 TI - Immunofluorescent study on early virus-cell interaction in Shope papilloma in vitro system. PMID- 4298706 TI - Experimental approaches to the determination of the nucleotide sequences of large oligonucleotides and small nucleic acids. PMID- 4298708 TI - [Cytomegalic inclusion disease in a newborn twin diagnosed by the isolation of a cytomegalovirus]. PMID- 4298707 TI - Ionic interaction of sulfatide with choline lipids. AB - Aqueous systems of sphingomyelin-sulfatide and lecithin-sulfatide were compared with aqueous systems of the individual lipids. The acid capacity of the mixed lipids increased, a result of the formation of an ionic bond between the sulfate of one molecule and the positive nitrogen of the other, making the phosphate available for direct titration. Cholesterol reduces this ionic interaction, probably because of the increased spacing of the ionized groups. PMID- 4298710 TI - The structure of regular viruses in relation to their subunit amino acid composition. PMID- 4298709 TI - Vinomycin I. The amino acid sequence of viomycin. PMID- 4298711 TI - The fine structure of vesicular stomatitis virus. PMID- 4298712 TI - The nucleic acid of the parainfluenza virus SV5. PMID- 4298713 TI - Productive and abortive infections of simian and nonsimian cells with a simian adenovirus SV15. II. Viral biosynthesis and effects of chemical inhibitors. PMID- 4298714 TI - Production of a potent complement-fixing murine leukemia virus-antiserum from the rabbit and its reactions with various types of tissue culture cells. PMID- 4298715 TI - Ornithine transcarbamoylase in Shope papilloma. PMID- 4298716 TI - [Studies on the sensitivity of grafts in the child]. PMID- 4298717 TI - [Current methods of study and morphologic findings in B-cell adenoma of the pancreas]. PMID- 4298718 TI - [On the physiopathology and surgery of hyperinsulinism]. PMID- 4298719 TI - [Progress in the clinical pathology of the adrenal cortex]. PMID- 4298720 TI - [The excretion of adrenal gland hormones after acute diseases, injuries and surgery]. PMID- 4298722 TI - Changes in circulating lymphocytes induced by the administration of ACTH in cocks. PMID- 4298721 TI - [Histochemical reaction of some dehydrogenases in the testis of rats, guinea pigs and mice after estrogen and ICSH treatment]. PMID- 4298723 TI - High blood pressure and oral contraceptives. Changes in plasma renin and renin substrate and in aldosterone excretion. PMID- 4298724 TI - Treatment of pseudomonas infection of the rabbit cornea. Comparative study. PMID- 4298725 TI - The diagnosis of trophoblastic tumours of testis. PMID- 4298726 TI - Acute and chronic effects of iodide on thyroid radioiodine metabolism in iodine deficient rats. PMID- 4298727 TI - Analysis of the Koritz-Hall hypothesis for the regulation of steroidogenesis by ACTH. PMID- 4298728 TI - [On the problem of sectional direction in nuclear wall pores in the electron microscopic picture]. PMID- 4298729 TI - In vitro neoplastic transformation of uveal and retinal tissue by oncogenic DNA viruses. PMID- 4298730 TI - Studies on the effect of bacterial endotoxin on primary herpetic keratitis. PMID- 4298731 TI - Metabolism of D-fructose in Aerobacter aerogenes: analysis of mutants lacking D fructose 6-phosphate kinase and D-fructose 1,6-diphosphatase. AB - The relative significance of the pathways for the conversion of d-fructose to d fructose 1,6-diphosphate via d-fructose 1-phosphate or d-fructose 6-phosphate in Aerobacter aerogenes PRL-R3 was assessed by observing growth patterns of mutants lacking either d-fructose 6-phosphate kinase or d-fructose 1,6-diphosphatase. The mutant lacking d-fructose 6-phosphate kinase grew well on d-fructose or glycerol but not on d-glucose, whereas the mutant lacking d-fructose 1,6-diphosphatase grew on d-glucose but not on d-fructose or glycerol. The data indicate that the pathway of d-fructose metabolism is primarily through d-fructose 1-phosphate rather than d-fructose 6-phosphate. PMID- 4298733 TI - Effect of age on the crystallinity of collagen. II. Density, reactivity, and composition. PMID- 4298734 TI - The effect of hypophysectomy on the aging of collagen fibers in the tail tendon of the rat. PMID- 4298732 TI - Purification and properties of L-alanine dehydrogenase from Desulfovibrio desulfuricans. AB - The l-alanine dehydrogenase from cell-free extracts of Desulfovibrio desulfuricans was purified approximately 56-fold. The Michaelis constants for the substrates of the amination reaction and the pH optima for the reactions catalyzed by this enzyme closely agree with those reported for other l-alanine dehydrogenases. Pyruvate was found to inhibit the amination reaction. The enzyme was absolutely specific for l-alanine and nicotinamide adenine dinucleotide. Its sensitivity to para-chloromecuribenzoate suggests that sulfhydryl groups may be necessary for enzymatic activity. These extracts also contained a nicotinamide adenine dinucleotide phosphate-specific glutamic dehydrogenase which was separated from the l-alanine dehydrogenase during purification. PMID- 4298735 TI - Preparation and screening of aminoacridines for induction of lung tumor fluorescence in rats. PMID- 4298736 TI - A treatment of corticosteroid-dependent lepromatous patients in persistent erythema nodosum leprosum. A clinical evaluation of G.30320 (B663). PMID- 4298737 TI - Malabsorption of iron secondary to iron deficiency. PMID- 4298739 TI - Effect of pH on the formation and intermolecular transfer of radiation-induced unpaired spins in frozen aqueous mixtures. PMID- 4298738 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1968. PMID- 4298740 TI - Free radical yields in polytetrafluoroethylene as the basis for a radiation dosimeter. PMID- 4298741 TI - Role of intermolecular reactions in the formation of secondary radicals in proteins irradiated in the dry state. PMID- 4298742 TI - [The role of the vegetative nervous system in the transmission of the distant effects of ionizing radiations]. PMID- 4298743 TI - [Secretion control of adrenal cortex hormones]. PMID- 4298744 TI - [Recent concept of primary aldosteronism]. PMID- 4298745 TI - [Adrenal cortex hyperfunction due to heterotopic ACTH-producing tumor (heterotopic ACTH syndrome)]. PMID- 4298746 TI - Cell proliferation: enhancement by extracts from cell surfaces of polyoma-virus transformed cells. AB - Dispersion of confluent monolayers of BHK21 cells with ethylenediaminetetraacetate yields a material that inhibits cell proliferation, whereas identical extraction of polyoma-virus-transformed cells provides material which enhances cellular proliferation. The material was partially characterized. PMID- 4298747 TI - Interferon: protection of cells infected with an intracellular protozoan (Toxoplasma gondii). AB - Chick and mouse cell monolayers treated with interferon were significantly protected from destruction by toxoplasma. The results suggest that fewer numbers of organisms were released from interferon-treated cells. Interferons were uniformly more active in a viral assay than in a toxoplasma assay, and they had the same properties in both assays. The data suggest that interferon activity may be directed against organisms phylogenetically higher than viruses. PMID- 4298748 TI - Effect of mesenteric traction on peripheral vascular resistance. PMID- 4298749 TI - [Cytomegalic inclusion disease]. PMID- 4298750 TI - [The use of micro-doses of copper and manganese in geriatrics]. PMID- 4298751 TI - [Experimental portal hypertension in chronic intrahepatic vascular occlusion]. PMID- 4298752 TI - Studies on the histochemical distribution of glucose-6-phosphatase, glucose-6 phosphate dehydrogenase, beta-glucuronidase and glucosan phosphorylase in olfactory bulb of rat. PMID- 4298753 TI - [On the enzyme histochemistry of rat ovary during postnatal development]. PMID- 4298755 TI - [On the utilization of enzyme histochemical methods for the classification of skin-pathogenic fungi]. PMID- 4298756 TI - [Anatomo-clinical aspects of malignant cholangioma. Review of literature and case report]. PMID- 4298754 TI - [Enzyme histochemical reaction patterns as indicators of the level of differentiation of epithelial skin tumors]. PMID- 4298757 TI - [Cytomegalic diseases]. PMID- 4298758 TI - [Differentiation potencies and clinical aspects of primary osteogenic sarcomas]. PMID- 4298759 TI - [Comparative studies of the acetate-2-14C incorporation in the mitochondriae lipids from liver and hepatoma]. PMID- 4298760 TI - [Partial angiectatic gigantism. (Klippel-Trenaunay-Weber syndrome)]. PMID- 4298761 TI - [Quantitative assay of phospholipids in rat heart muscles by means of thin-layer chromatography on silica gel]. PMID- 4298763 TI - [Inhibition of succinate oxidation by oxaloacetate]. PMID- 4298762 TI - [The protective effect of substrates under inactivation of NADH oxidase and succinate oxidase by cobra venom and trypsin]. PMID- 4298764 TI - [Succession in RNA synthesis in fibroblasts infected with Sendai virus]. PMID- 4298765 TI - [Characteristics of the nature and mechanism of action of plant folate reductases]. PMID- 4298766 TI - [Some physico-chemical characteristics of the complex of NAD-H2 and malate dehydrogenases in Micrococcus lysodeikticus membranes]. PMID- 4298767 TI - [Synthesis of uridilic nucleotides and TMP in bone marrow of chickens infected with avian myeloblastosis virus]. PMID- 4298768 TI - [Super-thin layer chromatography of vitamin B6 and its derivatives]. PMID- 4298769 TI - [The effects of substrates on the reconstitution of NADH-oxidase from its fragments]. PMID- 4298771 TI - [Glomus tumor of the esophagus]. PMID- 4298770 TI - [Radical formation in irradiated molecular mixtures of bovine serum albumin and organic mercaptans]. PMID- 4298772 TI - [Malignity and benignity of synovial blastomas. (Differential diagnosis and treatment)]. PMID- 4298773 TI - [On changes in thyroid function induced by ACTH during an operative intervention]. PMID- 4298774 TI - The effect of hyperbaric oxygen on the prevention of experimental C1. Welchii infection. PMID- 4298775 TI - [On the occupation risk of cement workers]. PMID- 4298776 TI - [The secretory mammary gland]. PMID- 4298777 TI - ["Calcium gout" with nephrocalcinosis due to long-term dihydrotachysterine therapy]. PMID- 4298778 TI - [Developmental trends and conformities in the hormone therapy of climacteric disorders]. PMID- 4298779 TI - Vasopressin test for corticotrophin release in man. PMID- 4298780 TI - The influence of chemical agents on the accumulation of adenosine 3',5'-Phosphate in slices of rabbit cerebellum. PMID- 4298781 TI - Studies on adenosine 3',5'-phosphate in rabbit cerebral cortex. PMID- 4298782 TI - Inhibition of activated lipolysis by acidosis. PMID- 4298784 TI - [Pulmonary histiocytoma]. PMID- 4298783 TI - [Nicotine and pentetrazol-induced EEG changes in normal and hypothyroid rabbits]. PMID- 4298785 TI - [Comparison of renin activity, angiotensin infusion test, separate urine studies according to Rapoport and isotope nephrogram in renal artery stenosis]. PMID- 4298786 TI - [Glycolysis and hexokinase activity in the subcellular fraction of the rabbit myocardium in adrenalinic myocarditis]. PMID- 4298788 TI - [Study of glutaminase and asparaginase activities in normal tissues and malignant tumors]. PMID- 4298787 TI - [Conversion of ribonucleotides in the blood of animals under the effect of RNA and insulin injections]. PMID- 4298789 TI - [Role of pyruvic acid in the Crabtree effect mechanism in NK/1y tumors]. PMID- 4298790 TI - [Fragmentation of liver DNA depending on the age of the animals]. PMID- 4298791 TI - [Comparative study on the inhibition effect of caprolactam and analogous compounds on kinins and factors of the fibrinolytic system]. PMID- 4298792 TI - [Studies on the problem of biological degradation of structural collagen]. PMID- 4298793 TI - Histochemical studies of glucose-6-phosphatase activity in the early proliferative stage of liver carcinogenesis. PMID- 4298794 TI - [The influence of a fractionated x-irradiation on the NAD-content of solid tumors and the host liver]. PMID- 4298795 TI - [Delayed type hypersensitivity in tumor-bearing rats]. PMID- 4298797 TI - [Thrombelastographic studies before and after radical vaginal uterus extirpations as well as during consequent radiotherapy (Coutard) in patients with and without thromboembolism prevention]. PMID- 4298796 TI - [The significance of aerobe mixed infection in gas gangrene]. PMID- 4298798 TI - Changes in the amount of adrenergic transmitter in the female genital tract of rabbit during pregnancy. PMID- 4298799 TI - Glucose metabolism and response to insulin of isolated fat cells and epididymal. fat pads. PMID- 4298800 TI - Effect of adrenaline, noradrenaline, angiotensin and renal nerve stimulation on intrarenal distribution of blood flow in dogs. PMID- 4298801 TI - Considerations on the cause of disappearance of the adrenergic transmitter in uterine nerves during pregnancy. PMID- 4298802 TI - Control of brain serotonin and norepinephrine by specific neural systems. PMID- 4298803 TI - Serotonin participation in the vagal inhibitory pathway to the stomach. PMID- 4298804 TI - Stimulation-induced release of serotonin. PMID- 4298805 TI - Discussion of stimulation-induced release of serotonin. PMID- 4298806 TI - Evidence for an excitatory transmitter role of serotonin in molluscan central synapses. PMID- 4298807 TI - Discussion of evidence for an excitatory transmitter role of serotonin in molluscan central synapses. PMID- 4298808 TI - Serotonin effects on central neurons. PMID- 4298809 TI - Granular cell myoblastoma of the breast. PMID- 4298810 TI - Necrotizing infections of subcutaneous tissue and fascia. PMID- 4298811 TI - Serological studies of the T and tumor antigens of the oncogenic simian adenoviruses. AB - Tumor-specific antigens and antisera were prepared for eight of the oncogenic simian adenoviruses. Complement-fixation tests revealed three distinct serological subgroups. This grouping was maintained in studies of virus-infected cells (T antigens) although high titered preparations were obtained for only the major subgroup I. The current grouping is as follows: (I) SV1, SV11, SV25, SV33, SV34, SV38; (II) SV20, SV23; (III) SA 7. Antigens from each subgroup were rapidly inactivated at 56 C, and group II and III antigens were also markedly inactivated at 37 C. One of the tumors (SV1) also contained SV40 T antigen, suggesting origin from a simian adenovirus-SV40 "hybrid." PMID- 4298812 TI - Effect of statolon-induced interferon on antibody formation. AB - The effect of statolon-induced interferon on immune response was investigated. Young adult Swiss albino mice were immunized with chicken red blood cells or infectious mengovirus. The red blood cells were injected three times and the virus twice at 2-week intervals, with or without treatment with statolon 24 hr before the inoculations. The effect of interferon on antibody formation was measured by determinations of hemagglutinating, hemolytic, and virus-neutralizing antibodies in the sera of treated and nontreated groups. The hemagglutinin and hemolysin titers after each successive inoculation were equal in both groups, indicating that interferon had no effect on their production. A decrease in the primary response to the viral antigen was associated with interferon induction; the booster response was unaffected. The possible use of interferon inducers as attenuants for immunization with live virulent viruses is discussed. PMID- 4298813 TI - Correlations between free radical production and viability of lyophilized bacteria. AB - When Serratia marcescens cultures were treated with dilute solutions of phenol or hydrogen peroxide before drying or by lyophilization at suboptimal pH, the log of the number of cells surviving lyophilization was correlated with subsequent free radical production by the dried cells. Since the rate of free radical production and rate of death were similarly affected by temperature, the log of the number of cells surviving after 6 days was inversely related to the free radical concentration at that time. Free radicals were produced in proportion to the log of oxygen pressure, and viability was inversely related to oxygen tension; again, free radical concentration appeared to be correlated with the death of organisms. PMID- 4298814 TI - Gas chromatographic detection of in vivo activity of equine infectious anaemia virus. PMID- 4298815 TI - Production of phosphatase by Aspergillus awamori var. kawachii in a low phosphate medium. AB - The effect of phosphate on the production of phosphatases by Aspergillus awamori var. kawachii was studied. In a high phosphate medium, little phosphatase was produced, and the phosphatase activity was predominately for beta glycerophosphate. In a low phosphate medium, the production of phosphatase was increased and activity for glucose-6-phosphate predominated. Medium containing 1 mg of phosphorus per 100 ml was optimal, and the amount of phosphatase produced in this medium was about 200 times that produced in a high phosphate medium. By means of column chromatography on diethylaminoethyl cellulose, the phosphatase produced in the high phosphate medium was found to be eluted mainly at fraction e; the phosphatase of the low phosphate medium was separated into fractions a, b, c, and d. Thus, the phosphatase fractions produced in the low phosphate medium were different from those of the high phosphate medium. Since no specific effect on the production of esterases was observed when various phosphate esters were used as substrates, the enzymes of phosphate metabolism appear to be activated by nonspecific phosphate sources. PMID- 4298817 TI - [Early diagnosis of acoustic tumors by electric gustometry]. PMID- 4298816 TI - Comparison of the capsular polysaccharides isolated from Klebsiella pneumoniae type 1, 2 and 3. PMID- 4298818 TI - Pharmacological actions of pseudoscopine and some of its derivatives. PMID- 4298819 TI - Hypophosphatasia: review and report of case. PMID- 4298820 TI - Lipid alterations in beagles produced by atherogenic stress and vitamin A. PMID- 4298821 TI - The relation between quantum content and facilitation at the neuromuscular junction of the frog. AB - 1. Experiments were done on the neuromuscular junction of the frog to study facilitation of the end-plate potential (e.p.p.) produced by one or more conditioning shocks applied to the motor nerve. Neuromuscular transmission was blocked with Mg (+)-tubocurarine chloride.2. In Mg-blocked preparations, facilitation increased with increasing Mg concentrations in the range 14-34 mM. The increase in facilitation was related specifically to the decrease in mean quantum content of the e.p.p., and was most marked with quantum contents less than 10.3. Facilitation in curarized preparations was similar in magnitude to that in preparations blocked with the lower Mg concentrations. Interaction between facilitation and depression in curarized preparations was consistent with the idea that facilitation was due to an increase in probability of transmitter release and depression to depletion of transmitter. PMID- 4298823 TI - [Case of tracheal adenoma]. PMID- 4298822 TI - [Case of bizarre leiomyoblastoma in the stomach]. PMID- 4298824 TI - [Epidemiological and serological studies of a swimming-pool focus of adenoviral infections]. PMID- 4298825 TI - Familial multiple endocrine adenopathy (primary hyperparathyroidism and Zollinger Ellison syndrome) in two siblings. PMID- 4298826 TI - Pigmented villonodular synovitis of the wrist joint. PMID- 4298827 TI - Solitary neural tuberculoid leprosy. PMID- 4298828 TI - [Malignant neoplasms of childhood. II. Radiodiagnostic premises]. PMID- 4298829 TI - [Lights and shadows in mammography]. PMID- 4298830 TI - [On eight studies of eosiophil granulomas of the maxilla]. PMID- 4298832 TI - [Resorption of primary tumors induced by virus SV40 in immunized animals]. PMID- 4298831 TI - [A case of mixed intrasinoidal tumor]. PMID- 4298833 TI - Angiofibroma in the frontal sinus of a dog. PMID- 4298836 TI - The role of cell membranes in the development of herpes virus. PMID- 4298835 TI - Isolation and properties of enterovirus receptors. PMID- 4298834 TI - [Tracing of viruses of tick-borne and Japanese encephalitis in cultures of transplanted cells using the fluorescent antibody method]. PMID- 4298837 TI - [Influence of some salts on the stability of the epizootic aphthous virus at temperature of 37 and 50 degrees C]. PMID- 4298838 TI - [Paroxysmal hemoglobinuria due to cold]. PMID- 4298840 TI - Geriatric clinics in local authority health centres. PMID- 4298841 TI - [Hygienic assessment of efficacy of hydroirrigation of the air in foundry cleaning rooms]. PMID- 4298839 TI - Spontaneous intraperitoneal rupture of primary liver-cell carcinoma. PMID- 4298843 TI - [Vascular effect of angiotensin]. PMID- 4298842 TI - Immunogenicity and specificity of collagen. V. Demonstration of three different antigenic determinants on calf collagen. PMID- 4298844 TI - [Insulin in the blood and in the tumor in nesidoblastomas. (Apropos of a personal case)]. PMID- 4298846 TI - Neurosurgical complications affecting the oculomotor, trochlear, and abducent nerves. PMID- 4298845 TI - hypertrophic interstitial neuropathy and cataracts. PMID- 4298847 TI - Delayed neurological sequelae of electrical injuries. PMID- 4298848 TI - Interagency planning for aftercare of mental patients in the community. PMID- 4298850 TI - [Content of ash and phosphorus, specific conductivity and phosphatase activity of light commercial honeys]. PMID- 4298849 TI - [Response of the adrenal gland cortex to synthetic ACTH (30.920-Ba) in normal patients and those with endocrine disorders]. PMID- 4298851 TI - [Breast tumors in men]. PMID- 4298853 TI - [On the removal from the register of patients with seroresistant syphilis]. PMID- 4298854 TI - [Angiofibroma of the stomach]. PMID- 4298852 TI - Radiocarbon: analysis of inorganic carbon of fossil bone and enamel. AB - Carbon dioxide from calcium carbonate in fossil bone can be selectively separated from carbon dioxide in bone apatite by hydrolyzing the sample first in acetic acid and then in hydrochloric acid. Radiocarbon analyses of the inorganic carbon dioxide in three samples of known age clearly show calcium carbonate in fossil bone to be secondary and the carbonate of bone apatite to be indigenous and suitable for dating in some cases. Agreement between dates on collagen-bone apatite pairs increases the level of confidence. PMID- 4298855 TI - [The effect of ACTH on some functions of the organism under "flat land" conditions and in the high mountains]. PMID- 4298856 TI - [Treatment with secondary antitubercular agents]. PMID- 4298857 TI - [Ultraweak luminescence of liver mitochondria in chemically induced carcinogenesis]. PMID- 4298858 TI - [Clinical aspects of serous meningitis of adenoviral etiology]. PMID- 4298859 TI - [The role of the nervous system in the development and outcome of peptone and allergic shock]. PMID- 4298860 TI - [The enzyme-histochemical behavior of the liver after intravenous papain application]. PMID- 4298861 TI - Soluble and particle-bound hexokinase in normal and tumour tissues of rats. PMID- 4298862 TI - [Neurons in the ventral cochlear nucleus, homolaterally stimulated by electrical stimulation on the base of the cochlear coil: centrifugal inhibition by contralateral sound application (guinea pigs)]. PMID- 4298863 TI - [Morphological-cytological contribution on the biological characteristics of the cylindroma]. PMID- 4298865 TI - [Corticotropo-corticoadrenal dynamics in prolonged cortisone treatment]. PMID- 4298864 TI - [Research on the lipid peroxidase inhibitors present in the cells of Yoshida ascites hepatoma]. PMID- 4298867 TI - [Lymphography and lymphoscintigraphy of the pelvis in venereal lymphopathy in the buboes condition]. PMID- 4298866 TI - [Micrognathism in an unusual malformation syndrome]. PMID- 4298868 TI - Preparation and structure-activity relationship of reagents for cytochrome oxidase activity: potential for light and electron microscopy. PMID- 4298869 TI - [The Papanicolaou method in the early diagnosis of intraductal cancer of the breast]. PMID- 4298870 TI - [Radiotherapy of malignant tumors of the maxillary sinus]. PMID- 4298872 TI - [On the influence of kinin hormones on gastric juice secretion. I. Effect of beta L-Asp-1-angiotensin II]. PMID- 4298871 TI - [Attempts at eradication of salmonella enteritis infections in children]. PMID- 4298873 TI - [On precocious puberty. I. Physiological principles and examination technics]. PMID- 4298874 TI - [Pyrophosphate levels of the urine in lithiasis]. PMID- 4298875 TI - [Nil nocere. Rachitis prevention in the newborn period]. PMID- 4298876 TI - [RNA containing tumor viruses]. PMID- 4298877 TI - [Depot-nitroglycerin for after care and rehabilitation following heart infarction]. PMID- 4298878 TI - [Studies on the mechanism of action of angiotensin on the isolated aorta preparation and on the blood pressure of rats and guinea pigs]. PMID- 4298879 TI - [Effect of diazepam on presynaptic inhibition and other spinal reflexes]. PMID- 4298881 TI - [Mechanical neuropathies]. PMID- 4298880 TI - [Action of acetylcholine, bradykinin and angiotensin on the liver blood flow of the anesthetized dog and on the pressure in the ligated ductus choledochus]. PMID- 4298882 TI - [The drug treatment of renal tuberculosis]. PMID- 4298883 TI - [Peripheral nervous system diseases in morbus Gaucher. New data based on electron microscopy]. PMID- 4298884 TI - [Endocrinal disorders of suprahypophyseal origin]. PMID- 4298885 TI - [Islet cell tumors not producing insulin]. PMID- 4298886 TI - [Animal experiment studies on the problem of small intestine motility in peritonitis]. PMID- 4298887 TI - [Diseases of the motoric end plate including myasthenia gravis]. PMID- 4298888 TI - [Conservative management of kidney calculi]. PMID- 4298889 TI - [Chemotherapy of malignant tumors as seen from the aspect of various specific laboratory studies]. PMID- 4298890 TI - [Studies on a senile female swamp lynx (Lynx rupelli Brandt) with special reference to the endocrine organs]. PMID- 4298891 TI - [Relationship between herpes zoster and gravidity, possibly exacerbation, also due to drugs]. PMID- 4298892 TI - [Progress in the diagnosis and therapy of trophoblastic tumors]. PMID- 4298893 TI - [Diagnostic value of pelvic angiography in trophoblastic tumors]. PMID- 4298894 TI - [Diagnostic and therapeutic value of selective transcutaneous catheterization of the hypogastric arteries and their branches in trophoblastic tumors]. PMID- 4298895 TI - [The immunological determination of chorionic gonadotropins in the diagnosis, prognosis and therapeutic control of trophoblastic tumors]. PMID- 4298896 TI - [Prospects of antiblastic chemotherapy in the treatment of autochthonous trophoblastic tumors. (Description of 2 clinical cases)]. PMID- 4298897 TI - [Catheterization of the pulmonary artery in regional chemotherapy for primary or metasatic localizations of trophoblastic tumors]. PMID- 4298898 TI - [In vitro methods of culture and identification of Rous sarcoma and poultry leucosis virus]. PMID- 4298899 TI - [The renin-angiotensin-aldosterone system in late gestosis]. PMID- 4298900 TI - [Jurubin, a nitrogen containing steroidsaponin of a new structural type from Solanum paniculatum L; concerning the structure of paniculidin]. PMID- 4298902 TI - [A case of congenital epulis]. PMID- 4298901 TI - [Frequency, etiology and therapy of subclinical azotemia in a cattle herd]. PMID- 4298903 TI - [Mediastinal chemodectoma]. PMID- 4298904 TI - Trench mouth in children. PMID- 4298905 TI - Lymphangiography. PMID- 4298906 TI - [Use of the microscope in surgery of the central nervous system]. PMID- 4298907 TI - [Clinical forms of diabetes and its therapeutic management]. PMID- 4298908 TI - [Tumors of the minor salivary glands]. PMID- 4298910 TI - [Research on the elimination of some enteric viruses in communities of children, in correlation with anti-poliomyelitis vaccination]. PMID- 4298909 TI - [Rhinoviruses]. PMID- 4298912 TI - Cytomegalovirus inclusion disease (CID): the cytomegalovirus. PMID- 4298911 TI - [Hydrogen transfer through coenzyme models in aqueous medium]. PMID- 4298913 TI - The influence of ACTH and adrenal cortex hormones on the reaction of the complement fixation test in the course of trichinellosis. PMID- 4298914 TI - [The care of denture wearers. A clinical psychologicial study]. PMID- 4298915 TI - [Electroencephalographic picture in a family with two brothers affected by pigmentary retinopathy, hypoacusia and polydactylia]. PMID- 4298916 TI - Angiotensin blood levels in hypovolemic shock during osmotic diuresis. PMID- 4298917 TI - Suppression of inflammation and histidine decarboxylase by protein synthesis inhibitors. PMID- 4298918 TI - Comparative chromatography of the chloroplast pigments. PMID- 4298919 TI - [Effect of preliminary treatment of Actinomycetes spores with ultrasound on the mutagenic effect of ultraviolet rays]. PMID- 4298920 TI - [Clearance of the body of the rabbit from polymyxin M]. PMID- 4298921 TI - Inhibition of cyclic 3',5'-nucleotide phosphodiesterase by phenothiazine and reserpine derivatives. PMID- 4298922 TI - DNA methylated in vitro by a monofunctional alkylating agent as a substrate for a specific nuclease from Micrococcus lysodeikticus. PMID- 4298923 TI - Cytochromes a and a3. Catalytic activity and spectral shifts in situ and in solution. PMID- 4298924 TI - Enzymatic reduction of nitrate with flavin nucleotides reduced by a new chloroplast NADH-specific diaphorase. PMID- 4298925 TI - Separation of microchonria, peroxisomes and lysosomes by zonal centrifugation in a Ficoll gradient. PMID- 4298927 TI - [Results obtained in Rumania in the contral of the last European epizootic of aphthous fever caused by type O virus]. PMID- 4298926 TI - A nitrite-reducing enzyme from Nitrosomonas europaea. Preliminary characterization with hydroxylamine ad electron donor. PMID- 4298928 TI - Experimental gas gangrene with food-poisoning Clostridium perfringens type A. PMID- 4298929 TI - [Bleeding from congenital vascular anomalies of the head and neck and from tumors]. PMID- 4298931 TI - [Tumors between benign and malignant. Semimalignancy, questionable dignity, precancerosis]. PMID- 4298930 TI - [Primary cancer of the free portion of the small bowel]. PMID- 4298932 TI - [Acne and acneiform eruptions]. PMID- 4298934 TI - [Clinically demonstrable organic disorders in alcoholism]. PMID- 4298933 TI - Nephrotoxicity of anti-infective drugs. PMID- 4298935 TI - Effect of alloxan diabetes and insulin administration on the incidence of pituitary necrosis caused by hexadimethrine bromide in rats. PMID- 4298936 TI - [Clinical studies on the adrenocorticotropic hormone. II. Studies on the mechanism of pituitary corticotropin secretion with synthetic lysine vasopressin]. PMID- 4298937 TI - Effect of Enovid on liver enzymes and accessory reproductive organs of male rat. PMID- 4298938 TI - Studies in experimental tuberculosis: effect of reduced food consumption in infected guinea-pigs on carbohydrate metabolism. PMID- 4298939 TI - Insulin-like activity in experimental tuberculosis and the effect of insulin administration on carbohydrate metabolism. PMID- 4298941 TI - Blood cholesterol levels, autochthonous intestinal flora and Clostridium perfringens recovery in rhesus monkeys fed a high sucrose diet. PMID- 4298940 TI - Studies on the phospholipids of mouse spleen on infection with Plasmodium berghei. PMID- 4298942 TI - Effect of corticotropin on aldosterone excretion and plasma renin in normal subjects, in essential hypertension and in primary aldosteronism. PMID- 4298943 TI - Effects of glucocorticoid administration on aldosterone excretion and plasma renin in normal subjects, in essential hypertension and in primary aldosteronism. PMID- 4298944 TI - Thyroxine transport and turnover in major nonthyroidal illness. PMID- 4298945 TI - Epinephrine synthesis in Cushing's syndrome. PMID- 4298946 TI - Tissue culture assay of helper activity of murine leukemia virus for murine sarcoma virus. PMID- 4298947 TI - Subcellular localization of tritium labeled vitamin D3 in rat intestinal mucosa. PMID- 4298949 TI - [Case of lung cancer with adrenal cortex hyperfunction]. PMID- 4298950 TI - [Primary adenoid carcinoma and adenocarcinoma of the midportion of esophagus]. PMID- 4298951 TI - [Autopsy case of juvenile hepatoma with liver cirrhosis due to schistosomiasis japonica]. PMID- 4298952 TI - [Diaplacental carcinogenic effect of diethylnitrosamine in rats]. PMID- 4298953 TI - Growth in suckling-mouse brain of "IBV-like" viruses from patients with upper respiratory tract disease. PMID- 4298954 TI - [Pituitary insufficiency occuring in an acromegalic patient 20 years after surgical intervention]. PMID- 4298955 TI - [What are the errors to avoid in the treatment of pulmonary tuberculosis?]. PMID- 4298956 TI - [New method of chemotherapy in psychiatry with a neuroleptic with prolonged effect: fluphenazine enanthate]. PMID- 4298957 TI - [Permeability of the blood-brain barrier in various blastomatous diseases of the brain and spinal cord]. PMID- 4298958 TI - [Wilms' tumor in a newborn infant]. PMID- 4298959 TI - [Clinico-morphological characteristics of vagus nerve tumors]. PMID- 4298960 TI - [Pneumography and pneumotomography in the diagnosis of tumors of soft tissues of the extremities]. PMID- 4298961 TI - [New therapeutic methods in chronic polyarthritis]. PMID- 4298962 TI - [Metabolic and functional regulation of the cardiovascular system during aging]. PMID- 4298963 TI - [Age dependent changes of body constitution based on adipose tissue and musculature evaluation]. PMID- 4298965 TI - [Clinical case contribution to the catamnesis of young woman after laryngectomy]. PMID- 4298964 TI - [Phosphatide metabolism of the intima in various forms of experimental arteriosclerosis]. PMID- 4298966 TI - [The significance of aerobe mixed infection in gas gangrene. II. The behavior of the Welch-Fraenkel gas gangrene bacillus in aerobic mixed infections (in vivo)]. PMID- 4298967 TI - [Characteristics of several circadian rhythms in patients with diencephalic pathologies]. PMID- 4298968 TI - The biochemistry of supporting materials in organisms. PMID- 4298969 TI - [Histochemical study of the distribution of acetyl cholinesterase and NAD diaphorase in the human brain]. PMID- 4298970 TI - [Intra-peritoneal embryonic tumor presumably of nephrogenic origin, Wilms' type of tumor, but with 2 normal kidneys, in an adolescent of 15 years]. PMID- 4298971 TI - The effect of 5-iodo-2'-deoxyuridine on herpes simplex virus infections in guinea pig skin. PMID- 4298973 TI - The interaction between phosphoryl transferase and submitochondrial particles. PMID- 4298972 TI - Oxidative phosphorylation in Escherichia coli. PMID- 4298974 TI - Histochemical studies on deoxyribonuclease activity in normal and azo dye-fed rat livers by the modified phosphatase method. PMID- 4298975 TI - Activity of the cell-sap factor inhibiting DNA synthesis of rat ascites hepatoma cells in normal tissues, various malignant and minimal deviation hepatomas, as well as livers during the course of carcinogenesis. PMID- 4298976 TI - Some characteristics in the pathway of RNA synthesis in hepatoma cells. PMID- 4298977 TI - Sensory traces versus the psychological moment in the temporal organization of form. PMID- 4298978 TI - ACTH versus corticosteroids. PMID- 4298979 TI - Presence of deoxycompounds in irradiated carbohydrates. PMID- 4298980 TI - Cooperative study in the evaluation of therapy in multiple sclerosis; ACTH vs placebo in acute exacerbations. Preliminary report. PMID- 4298981 TI - An hypothesis for the action of vitamin D on bone. PMID- 4298982 TI - [Acute ulceronecrotic enterocolitis in infants. Relationship with cytomegalia]. PMID- 4298984 TI - [Identification of the defective sarcoma RVA-2 virus by means of the mouse leukemia virus]. PMID- 4298983 TI - [To the problem of the mechanism of inhibition of some pathologic processes under the effect of additional nonspecific stimulants]. PMID- 4298985 TI - Properties of Aujeszky's disease virus strains isolated from swine pneumonia cases. Prelininary report. PMID- 4298986 TI - Aspects of glycogen synthesis and degradation. PMID- 4298987 TI - The diagnosis and management of the glycogen storage diseases. PMID- 4298988 TI - Phosphorescence from sulfur-containing bases in Escherichia coli t-RNA. PMID- 4298989 TI - An E. coli mutant with cryptic UDP-sugar hydrolase and altered metabolite regulation. PMID- 4298990 TI - Vesicular stomatitis virus RNA: complementarity between infected cell RNA and RNA's from infectious and autointerfering viral fractions. PMID- 4298992 TI - II. The dissociation of the alcohol dehydrogenases. PMID- 4298991 TI - The mechanism of action of UDPG dehydrogenase. PMID- 4298993 TI - Inhibition by citrate of pyruvate dehydrogenase in rat liver mitochondria. PMID- 4298994 TI - The role of ubiquinone in the respiratory chain of Acetobacter xylinum. AB - 1. Whole cells of Acetobacter xylinum were found to contain a quinone of the ubiquinone (coenzyme Q) group. The quinone was isolated from the cells and crystallized. It was identified by its physical, chemical and spectroscopic properties as a ubiquinone with 10 isoprene units (ubiquinone-10). No naphthaquinone was detected in the cells. 2. Cell-free extracts prepared by means of a French pressure cell were separated into three fractions by differential centrifugation. The ubiquinone was located predominantly in the particulate fraction sedimenting at 33000g, which also contained most of the NADH oxidase and malate oxidase activities. The concentration of ubiquinone-10 in extracts was similar to that of the flavoproteins and about three times the concentration of the individual cytochromes. 3. Aerobic incubations of crude extracts with either NADH or malate resulted in reduction of the endogenous ubiquinone-10 to steady state concentrations of 55 and 40% of the total quinone respectively. In the presence of cyanide more than 95% of the endogenous ubiquinone-10 was reduced by either NADH or malate. 4. The initial rate of reduction of endogenous ubiquinone 10 by malate and the rate of ubiquinol oxidation, in A. xylinum extracts, were found to be compatible with the overall rate of malate oxidation with oxygen. 5. The effects of various respiratory inhibitors on the oxidation-reduction reactions of the endogenous quinone indicate that its position on the respiratory chain is between the malate flavoprotein dehydrogenase and the cytochrome chain. PMID- 4298995 TI - Studies on ferrochelatase. The enzymic formation of haem in proplastids, chloroplasts and plant mitochondria. AB - 1. Ferrochelatase was demonstrated in the chloroplasts and proplastids isolated from the primary leaves of beans (a dicotyledon) and oats (a monocotyledon). It was also detected in chloroplasts from etiolated bean seedlings made green by illumination before being harvested. The specific activities of the three types of bean organelles are similar, as are the specific activities of the oat proplastids and chloroplasts. 2. Chloroplasts from young spinach leaves also contain ferrochelatase; these chloroplasts were tested for their ability to form magnesium tetrapyrroles and found unable to catalyse the insertion of Mg(2+) into mesoporphyrin IX. 3. Ferrochelatase was also detected in potato tuber mitochondria. 4. Ferrochelatase activity in these plant preparations is much less stable on storage than similar preparations from bacteria and animal tissues. 5. Temperature affects the activities of spinach chloroplast ferrochelatase and rat liver ferrochelatase differently. Activity of the chloroplast enzyme increases as the temperature rises from 20.6 degrees to 26 degrees , but becomes increasingly inactivated as the temperature rises further to 38 degrees . The initial velocity of the mammalian enzyme, however, increases as the temperature rises from 25.8 degrees to 65 degrees , but the enzyme is inactivated after several minutes at 65 degrees . PMID- 4298996 TI - A temperature-induced lesion in amino acid-transfer ribonucleic acid attachment in a psychrophile. PMID- 4298997 TI - Incorporation of specifically labeled [14C] glucose into herpes simplex DNA. PMID- 4298998 TI - Amino acid content and elemental composition of selected strains of Clostridium perfringens. PMID- 4298999 TI - Tumorigenicity of N-nitrosohexamethyleneimine. PMID- 4299000 TI - Soluble RNA ethylase activity of normal and neoplastic mouse tissues. PMID- 4299001 TI - The establishment of a cell line of human hormone-synthesizing trophoblastic cells in vitro. PMID- 4299002 TI - Verrucae: virus structure, localization of antigens, and comparison with the Shope papilloma. PMID- 4299003 TI - Myelin as a locus for radioantibody absorption in vivo in brain and brain tumors. PMID- 4299004 TI - The study of normal and malignant cell antigens by mixed agglutination. PMID- 4299005 TI - Action of a neutral lipid fraction on arterial blood pressure of adrenalectomized or hypophysectomized cats. PMID- 4299007 TI - [Concerning the action of solasodine on the adrenal glands]. PMID- 4299008 TI - Avian leucocytic responses induced by stress and corticoid inhibitors. PMID- 4299006 TI - [On the mechanism of action of imidazole- and pyrazoledicarboxylic acid derivatives on the pituitary-adrenal system]. PMID- 4299009 TI - Adenovirus infections in Delhi: isolation from tonsils and a serological survey. PMID- 4299010 TI - Use of ultrasonic aerosols with ventilatory assistors. PMID- 4299011 TI - Aldosterone hypersecretion in "non-salt-losing" congenital adrenal hyperplasia. AB - Patients with the "non-salt-losing" form of the adrenogenital syndrome were studied before and after suppression of adrenal cortical activity with carbohydrate-active steroids. The response of aldosterone secretion to sodium deprivation was measured; in some patients response to adrenocorticotropic hormone (ACTH) was measured as well. The aldosterone secretion was normal and responded normally to sodium deprivation in all patients studied during suppression with carbohydrate-active steroids. This finding suggests that 21 hydroxylation of progesterone is normal in this syndrome. The sole abnormality in the production of aldosterone in these patients was found to be excessive secretion of aldosterone while they were not receiving suppressive doses of carbohydrate-active steroids. This finding strongly supports the view that the biogenetic pathways through which aldosterone is produced from progesterone are intact in this syndrome. No patient showed hypertension or hypokalemic alkalosis despite very high aldosterone secretion rates. This observation suggests that the hyper-aldosteronism is secondary to a tendency to sodium loss in the patient whose ACTH production is not suppressed. These studies provide additional evidence in support of the hypothesis that the salt-losing and "non-salt-losing" forms of adrenogenital syndrome are genetically and biochemically distinct. PMID- 4299012 TI - Effect of dibutyryl cyclic adenosine 3',5'-monophosphate, theophylline, and other nucleotides upon calcium and phosphate metabolism. AB - The effect of dibutyryl cyclic adenosine 3',5'-monophosphate upon calcium and phosphate metabolism in thyroparathyroidectomized rats was undertaken in an effort to clarify the possible role of adenosine 3',5'-monophosphate (3',5' AMP) in parathyroid hormone action. The infusion of dibutyryl cyclic 3',5' AMP at a rate of 3 mg/hr into thyroparathyroidectomized rats leads to changes in calcium, phosphate, and hydroxyproline excretion, and calcium and phosphate concentrations in plasma that are qualitatively similar to those induced by parathyroid hormone given at a rate of 5 mug/hr. The effect of dibutyryl cyclic 3',5' AMP upon calcium and hydroxyproline mobilization from bone is blocked by thyrocalcitonin administration in the same way that thyrocalcitonin blocks PTH effects. Other closely related nucleotides do not act in the same way. These data indicate that dibutyryl cyclic 3',5' AMP produces effects similar to parathyroid hormone in thyroparathyroidectomized rats, and support the notion that 3',5' AMP is an intermediate in the mechanism of PTH action. However, the changes in magnesium and potassium excretion are different after dibutyryl cyclic 3',5' AMP infusion from those seen after PTH infusion. Also, theophylline was found to potentiate the action of smaller doses of dibutyryl 3',5' AMP, but not that of PTH. PMID- 4299013 TI - A direct synaptic connexion between the left and right giant cells in Aplysia. AB - 1. In Aplysia fasciata, intrasomatic stimulation of the giant cell (RGC) of the right upper quadrant of the abdominal ganglia is followed after a constant delay by the appearance of a synaptic potential recorded in the giant cell (LGC) of the left pleural ganglion.2. The synaptic potential recorded in the LGC soma has a biphasic form (hence biphasic post-synaptic potential or BPSP) consisting of a fast depolarizing phase of about 200-800 muV amplitude and 0.15-0.25 sec duration, followed by a slow hyperpolarizing phase of about 200-800 muV amplitude and 1-3 sec duration.3. During repetitive stimulation summation results in an over-all hyperpolarization at low frequencies (less than 5/sec) and an over-all depolarization for higher frequencies. Very high frequencies (25/sec) of stimulation of the RGC may elicit a spike in the LGC.4. Stimulation with two shocks showed increasing effects with shorter intervals on both the depolarizing and hyperpolarizing phase. These effects were progressive and there was no falling out of one of the two phases as might be expected if the BPSP was a composite of an inhibitory post-synaptic potential (IPSP) and an excitatory post synaptic potential (EPSP).5. The effects of artificially imposed polarization of the LGC through a second micro-electrode suggest that the BPSP results from a chemical transmission mechanism for both its depolarizing and hyperpolarizing phases but electrical transmission cannot be excluded.6. Curare has no effect on the BPSP and thus excludes a cholinergic transmission mechanism. Chloride ions injected into the LGC soma do not appear to modify the BPSP and hence it is concluded that the hyperpolarizing phase is different from IPSPs of the same cell.7. No synaptic potential is recorded in the RGC following stimulation of the LGC, except in a single preparation in which the RGC soma was situated in the right pleural ganglion. In this case the synaptic potential recorded in both giant cells following stimulation of the other, was biphasic in form.8. It is concluded that the BPSP is a unitary monosynaptic potential which is a characteristic feature of the organization of these two giant cells. PMID- 4299015 TI - Greater specificity of 19S than 7S antibodies on haemagglutination-inhibition tests with closely related group B arboviruses. PMID- 4299014 TI - An examination of the effects of osmotic pressure changes upon transmitter release from mammalian motor nerve terminals. AB - 1. When the frequency of miniature end-plate potentials (m.e.p.p.s) was measured at neuromuscular junctions in rat diaphragm nerve preparations in vitro bathed in solutions having osmolarities between 200 and 700 m-osmoles/l. it was found that m.e.p.p. frequency was transiently increased by exposure to osmotic gradients exceeding 75 m-osmoles/l., and then declined, within 1 hr, to a steady level slightly higher than the control level of frequency. Smaller osmotic gradients caused a maintained increase in m.e.p.p. frequency. E.p.p. quantal content was initially increased and later profoundly decreased upon exposure of preparations to solutions with an osmotic pressure of 500 or 600 m-osmoles/l. but was unaffected by less hypertonic solutions.2. Variation of the Ca or Mg content of the bathing solutions did not alter these effects of osmotic pressure on the early transient increase in m.e.p.p. frequency or e.p.p. quantal content but affected the late steady increase in m.e.p.p. frequency.3. The value of the transient increase in m.e.p.p. frequency was exponentially related to the osmotic gradient in the range 0-300 m-osmoles/l. with a Q(10) of 1.95 (range 11-34 degrees C). Greater osmotic gradients did not further increase m.e.p.p. frequency. Variation of the ionic strength of the bathing medium did not influence osmotic effects upon frequency.4. The discrepancy between the effects of osmotic gradients upon spontaneous and nerve-impulse induced transmitter release was explained by an occlusion of the osmotic effects by depolarization of nerve terminals. Time-course studies showed that in the presence of 20 mM-KCl the m.e.p.p. frequency increase in response to an increase in osmotic pressure was small and was followed by a reduction in frequency to below control levels while osmotic pressure changes had no immediate effect upon m.e.p.p. frequency in solutions containing 30 mM-KCl.5. It was concluded that increased osmotic gradients could release transmitter by a mechanism independent of Ca and of nerve terminal depolarization.6. It is suggested that the initial transient effects of changes of osmotic gradient upon transmitter release are related to flow of water through the nerve terminal membrane, while the later effects are related to nerve terminal volume changes. PMID- 4299016 TI - Cytochrome oxidase activity during treatment of copper deficiency. PMID- 4299017 TI - Management of colostomy, ileostomy, and ileal conduit. PMID- 4299020 TI - [Antigen components of the poliovirus in the complement fixation test]. PMID- 4299019 TI - [Study on adrenocortical function in functional menstrual disorders]. PMID- 4299018 TI - Quantitative measurement of inhibition of aliesterases, acylamidase, and cholinesterase by EPN and Delnav. PMID- 4299021 TI - [Antibodies against para-influenza-3-virus in agricultural domestic animals in Syria]. PMID- 4299022 TI - Histochemical localization of alkaline ribonuclease and phosphodiesterase I in the central nervous system of the rat. PMID- 4299023 TI - [Effect of noradrenalin, adrenalin, ACTH and hydrocortisone on the mobilization of free fatty acids in endotoxic fever and during normal body temperature]. PMID- 4299024 TI - [Nonbacterial endocarditis caused by carcinoma of the pancreas]. PMID- 4299025 TI - [Contribution to the diagnosis of cylindroma of the tongue]. PMID- 4299026 TI - [Management of mental and autonomic disorders in the climacterium]. PMID- 4299027 TI - [Scope and tasks of the specialty neurosurgery]. PMID- 4299028 TI - [Microadenomatosis of the pancreas as the cause of hyperinsulinism]. PMID- 4299029 TI - [On the surgical treatment of tumors of the parotid gland]. PMID- 4299030 TI - [Electroencephalography in malignant tumors of the brain]. PMID- 4299031 TI - [Clinico-etiological and therapeutic aspects of peripheral facial paralysis]. PMID- 4299032 TI - [Recent fundamentals on tumor therapy]. PMID- 4299033 TI - [Mycoplasma infections of the respiratory tract]. PMID- 4299034 TI - [Use of elementary electromyography in the diagnosis of neuromuscular diseases]. PMID- 4299035 TI - Evidence for a precursor in the biosynthesis of insulin. PMID- 4299036 TI - The survival of the virus of infectious laryngotracheitis. PMID- 4299037 TI - [The dose dependent adrenocorticotropic effect of beta-1-24-corticotropin in comparison with natural ACTH]. PMID- 4299038 TI - [The effect of single or long-term administration of 3'-methyl-4 dimethylaminoazobenzole on various metabolic functions of the rat liver]. PMID- 4299039 TI - [Surgical management of peripheral hypoplasia of the hand]. PMID- 4299040 TI - [Cow pox in the light of present modern virological knowledge]. PMID- 4299041 TI - [Technique of the COFAL test]. PMID- 4299042 TI - [The importance of complement fixing antibodies in natural rhinopneumonitis infection in gravid mares]. PMID- 4299043 TI - Induction of a high incidence of damage to the X chromosomes of Rattus (Mastomys) natalensis by base analogues, viruses, and carcinogens. PMID- 4299044 TI - [Estrogens in ophthalmology. Experimental studies]. PMID- 4299045 TI - Primary carcinoma of the liver in infancy. Report of a case. PMID- 4299046 TI - [Occurrence of enteroviruses in healthy children in Bulgaria]. PMID- 4299047 TI - [On the chemistry of the bensolglycols, XVI. Synthesis of inositol monophosphates]. PMID- 4299048 TI - [Pospischill-Feyrter aphthoid]. PMID- 4299050 TI - [Tolerance to viomycin, at the same time a report on experience with intravenous application]. PMID- 4299049 TI - [Effect of ATP, cyclic AMP, adenosine and dipyridamole on isolated helical strips from the protal vein, renal and coronary arteries]. PMID- 4299051 TI - [Study of the orbit with contrast media]. PMID- 4299052 TI - [Serologic study of para-influenza in Spain]. PMID- 4299053 TI - [The currently suitable laboratory diagnosis of the adrenal gland cortex function]. PMID- 4299054 TI - [A case of dysplasia acrodentalis]. PMID- 4299055 TI - The use of an in vitro test of delayed type hypersensitivity for the detection of specific tumor antigen of transplantation type induced by SV 40 virus. PMID- 4299056 TI - [Substitution plasty in meso- and pharyngeal tumors. Special part]. PMID- 4299057 TI - [On the reconstruction of nose defects]. PMID- 4299058 TI - [Immune adherence assay of virus specific antigens and antibodies. I. Elaboration of the method with Herpesvirus hominis and its serological specificity]. PMID- 4299059 TI - [Phosphatases of staphylococci and micrococci]. PMID- 4299060 TI - [Studies on the glycogen content in neuroepithelial brain tumors]. PMID- 4299061 TI - [The steroid ulcer: its pathogenesis, occurrence, localization and sex pertinence]. PMID- 4299062 TI - [The surgical management of bronchial adenoma]. PMID- 4299063 TI - [Malignant glomus tumor of the stomach]. PMID- 4299064 TI - Transmission of atrial waves to the blood vessels of the digits and outer ear in cases of atrial flutter. PMID- 4299065 TI - Effect of brief carotid sinus pressure on digital vascular tone. PMID- 4299066 TI - Effect of rapid distension of large arteries and veins on the vascular tone of the fingers. PMID- 4299067 TI - Hypermineralocorticoidism. PMID- 4299068 TI - The metopirone test of pituitary corticotrophin release. Evaluation of 101 tests. PMID- 4299070 TI - Prodromal trigeminal sensory neuropathy in progressive systemic sclerosis. PMID- 4299069 TI - Incidence and clinical significance of tumor embolization to the lungs. PMID- 4299071 TI - [Development of antibiotic chemistry in the USSR]. PMID- 4299072 TI - Plasma renin and angiotensinogen levels in pathological states associated with oedema. PMID- 4299073 TI - [On negative results in the cell-free transplantation attempts of chemically induced sarcomas]. PMID- 4299074 TI - [Lysogeny and viral cancerogenesis]. PMID- 4299075 TI - [Postsynaptic, auditory, crossed, efferent inhibition in ventral cochlear nucleus and its blockade by strychnine nitrate (in guinea pigs)]. PMID- 4299076 TI - Motor conduction in the deep palmar branch of the ulnar nerve. PMID- 4299077 TI - Conformational transition in biological membrane studyed by the spin label method. PMID- 4299078 TI - Selection of fructose 6-phosphate kinase mutants in Escherichia coli. PMID- 4299079 TI - Activation of malate-linked reductions of NAD and flavoproteins in Ascaris muscle mitochondria by phosphate. PMID- 4299081 TI - Identification of the major glycolipid from Mycoplasma sp., strain J as 3,4,6 triacyl-beta-Glucopyranose. PMID- 4299080 TI - An NADH dependent cleavage of DTNB by the alpha-ketoglutarate dehydrogenase complex. PMID- 4299082 TI - A charge-transfer intermediate in the mechanism of reduced diphosphopyridine nucleotide oxidation by ferric ions. PMID- 4299083 TI - The reduction of ferric o-phenanthroline complexes by reduced diphosphopyridine nucleotide. PMID- 4299084 TI - Transfer ribonucleic acids in Escherichia coli. Multiplicity and variation. PMID- 4299085 TI - Lipid class and fatty acid composition of rat liver plasma membranes isolated by zonal centrifugation. PMID- 4299086 TI - Phosphatidate phosphohydrolase activity in liver cell surface membranes. PMID- 4299087 TI - Viral antibody levels and clinical status in acute exacerbations of chronic bronchitis: a controlled prospective study. AB - A controlled prospective study was made of a group of patients with chronic bronchitis, in which serum antibodies against a group of viruses and Mycoplasma pneumoniae were estimated at regular intervals. Sixteen significant rises in antibody titre were shown, of which eight were associated with clinical acute exacerbations of bronchitis. In individual patients no correlation was found between the number of acute exacerbations or the aetiological agent and persistent change in ventilatory function as expressed by the F.E.V.(0.75).This study was compared with the results of a previous parallel investigation of the same patients done to study the significance of rhinovirus infections. In the present investigation 12% of the acute exacerbations were associated with the 11 agents tested compared with 14% associated with rhinoviruses in the earlier work. PMID- 4299089 TI - [The role of pancreatic diagnosis for the correct indication for pancreatic surgery]. PMID- 4299090 TI - Neurovascular syndromes related to the clavicle. PMID- 4299092 TI - Brain stem pathways modifying activity in the tuberal region of the hypothalamus. PMID- 4299091 TI - Preoperative preparation and postoperative care of the colon. PMID- 4299093 TI - [Angiography of the vertebral artery through selective catheterization and its results]. PMID- 4299094 TI - Peptide hormones in plasma. PMID- 4299095 TI - The evolution of primary aldosteronism: 1954-1967. PMID- 4299096 TI - Identity of nuclear NAD nucleosidase with a polyADP-ribose forming enzyme in Ehrlich ascites tumor cells. PMID- 4299097 TI - Elicitation of skin test reactions by complexes of penicillin or its derivatives with solubilized erythrocyte stroma receptors. PMID- 4299098 TI - Cancer of the breast with metastasis to the fallopian tube. PMID- 4299099 TI - Influence of photoirradiation on the oxidation-reduction state of thioredoxin reductase. PMID- 4299100 TI - Studies on the action of insulin in isolated adipose tissue cells. I. Stimulation of incorporation of 32P-labeled inorganic phosphate into mononucleotides in the absence of glucose. PMID- 4299101 TI - Inhibitors of protein biosynthesis. V. Effects of emetine on protein and nucleic acid biosynthesis in HeLa cells. PMID- 4299102 TI - Malic dehydrogenase. VII. The catalytic mechanism and possible role of identical protein subunits. PMID- 4299104 TI - Adrenergic neurons in the cat superior cervical ganglion and cervical sympathetic nerve trunk. A histochemical study. PMID- 4299103 TI - Physicochemical studies of the carcinoembryonic antigens of the human digestive system. AB - A procedure has been described for the purification of the carcinoembryonic antigens (CEA) of the human digestive system. Tumor tissue extraction in 0.6 M perchloric acid followed by paper block electrophoresis and column chromatography on Sephadex G-200 resulted in highly purified CEA preparations as determined by both immunological and physicochemical criteria. The properties and composition of five different purified CEA preparations derived from digestive system cancer metastases were examined. The findings demonstrated a high degree of uniformity amongst these samples. Sedimentation coefficients ranged from 6.9 to 8S. Each sample showed the presence of 14 different amino acid residues and six different carbohydrate constituents (four of which could be quantitated with the amount of material available for analyis). Studies of a purified CEA preparation from a primary hepatoma yielded results which, in some respects, differed from those obtained with the CEA samples of metastatic tumor origin. The implications of these variations were discussed with regard to the probable presence of non-CEA components in the hepatoma preparation. Of primary importance was the observation that the few normal adult digestive system tissues tested failed to show the presence of constituents similar to the CEA. This finding would seem to indicate that, in the adult, the carcinoembryonic antigens of the human digestive system are qualitatively tumor-specific and are not dectectable in comparable normal tissues. PMID- 4299105 TI - Studies on the cortical control of the adrenal medulla in the rat. PMID- 4299106 TI - Effect of inhalation anesthetics on monosynaptic and plysynpatic transmission in the spinal cord. PMID- 4299107 TI - Antagonism of experimental cyanide toxicity in relation to the in vivo acitivity of cytochrome oxidase. PMID- 4299108 TI - [Organic acids and shock states]. PMID- 4299109 TI - Detection of biologically defective molecules in component I of polyoma virus DNA. PMID- 4299110 TI - Thrombin-induced platelet release reaction and platelet lysosomes. PMID- 4299111 TI - Transfer of Rous virus genome from rat tumour cells to chick cells at high temperature. PMID- 4299112 TI - Congenital cytomegalic inclusion disease with porencephaly. PMID- 4299113 TI - [Exchange transfusion and hemodialysis in Clostridium perfringens sepsis after illegal abortion]. PMID- 4299114 TI - Corticofugal control of the presynaptic inhibition in the spinal trigeminal nucleus of the cat. The effect of pyramidotomy and barbiturates. PMID- 4299115 TI - [Ninhydrin test and sensory nerve action potentials in the clarification of peripheral nerve lesions. Comparative studies]. PMID- 4299116 TI - Replication of polyoma virus DNA. I. A resting cell system for biochemical studies on polyoma virus. PMID- 4299117 TI - [Diagnostic difficulties in malignant synovioma]. PMID- 4299118 TI - A discssion of control of brain serotonin and norepinephrine by specific neural systems. PMID- 4299119 TI - The metabolism of the alkylphosphate antagonists and its pharmacologic implications. PMID- 4299120 TI - Antiviral agent from lambda-infected Escherichia coli K-12. I. Isolation. AB - Phagicin, which is an antiviral agent active against deoxyribonucleic acid (DNA) viruses such as vaccinia and herpes simplex, has been identified as a phage internal protein. It was found in infected Escherichia coli lysates, but could also be obtained by disruption of the purified infective particles after incubation with LiCl at 46 C for 15 min or by sonic treatment. After centrifugation at high speed, the antiviral activity was found in the DNA phase and could be separated by chromatography on Sephadex gels with 0.2 M phosphate buffer (pH 7.5) as the eluent. Phagicin present in lysates after removal of infective particles was nondialyzable and was bound to nucleic acids. It could be released during precipitation of nucleic acids by streptomycin sulfate, and in this form it could be easily dialyzed. The antiviral activity of phagicin was specific for herpes simplex and vaccinia viruses. PMID- 4299121 TI - Syndactylism, dyschromia, and the arsenical dilemma. PMID- 4299123 TI - Treatment problems leading to readmissions of schizophrenic patients. PMID- 4299122 TI - Eccrine poroma. PMID- 4299124 TI - [Induced fluorenscence in the study of tissue culture cells infected with viruses. 3. Nnucleic acids in tissue culture cells infected with Picorna viruses]. PMID- 4299125 TI - Interaction of polypeptide hormones with lipid monolayers. AB - 1. The interaction between lipid monolayers spread on the surface of water and oxytocin, [8-arginine]-vasotocin and [1-asparagine-5-valine]-angiotensin II in the subphase was investigated in a Langmuir surface trough by studying the changes in pressure produced on injection of various quantities of the polypeptide solution under the film. 2. The effect of 2m- and 4m-urea on the character of the adsorption is reported. 3. Structures for the adsorbed films formed in this way are suggested. 4. If the lipid monolayer is taken as a suitable model of cell membranes, then it may be supposed that the effect of such structures forming in cell membranes would be to provide effective ;pores' to facilitate the movement of water and other small molecules across the membrane. PMID- 4299126 TI - A comparison of the effects of NN'-dicyclohexylcarbodi-imide, oligomycin A and aurovertin on enrgy-linked reactions in mitochondria and submitochondrial particles. AB - 1. The effects of dicyclohexylcarbodi-imide, oligomycin A and aurovertin on enzyme systems related to respiratory-chain phosphorylation were compared. Dicyclohexylcarbodi-imide and oligomycin A have very similar functional effects, giving 50% inhibition of ATP-utilizing and ATP-generating systems at concentrations below 0.8nmole/mg. of submitochondrial-particle protein. Aurovertin is a more potent inhibitor of ATP synthesis, giving 50% inhibition at 0.2nmole/mg. of protein. However, aurovertin is a less potent inhibitor of ATP utilizing systems: the ATP-driven energy-linked nicotinamide nucleotide transhydrogenase is 50% inhibited at 3.0nmoles/mg. of protein and the ATP-driven reduction of NAD(+) by succinate is 50% inhibited at 0.95nmole/mg. of protein. 2. With EDTA-particles (prepared by subjecting mitochondria to ultrasonic radiation at pH9 in the presence of 2mm-EDTA) the maximum stimulation of the ATP-driven partial reactions is effected by similar concentrations of oligomycin A and dicylcohexylcarbodi-imide, but the latter is less effective. The stimulatory effects of suboptimum concentrations of dicyclohexylcarbodi-imide and oligomycin A are additive. Aurovertin does not stimulate these reactions or interfere with the stimulation by the other inhibitors. 3. Dicyclohexylcarbodi-imide and oligomycin A stimulate the aerobic energy-linked nicotinamide nucleotide transhydrogenase of EDTA-particles, but the optimum concentration is higher than that required for the ATP-driven partial reactions. Aurovertin has no effect on this reaction. 4. The site of action of dicyclohexylcarbodi-imide is in CF(0), the mitochondrial fraction that confers oligomycin sensitivity on F(1) mitochondrial adenosine triphosphatase. PMID- 4299127 TI - The redox state of the nicotinamide-adenine dinucleotides in rat liver homogenates. AB - 1. The redox state of the NAD couple of rat liver mitochondria, as measured by the [beta-hydroxybutyrate]/[acetoacetate] ratio, rapidly changed in the direction of oxidation during the preparation of homogenates in a saline medium. The value of the [beta-hydroxybutyrate]/[acetoacetate] ratio fell from 2.3 to 0.15 in 10min. EDTA diminished the fall and succinate prevented it. 2. The redox state of the rat liver cytoplasm, as measured by the [lactate]/[pyruvate] ratio, changed slightly in the direction of reduction during the preparation of homogenate. This was prevented by succinate. 3. In unsupplemented homogenates the differences in the redox states of mitochondria and cytoplasm decreased. Succinate and EDTA together maintained the differences within the physiological range. A measure of the ability of the mitochondria to maintain different redox states in mitochondria and cytoplasm is the value of the expression [lactate][acetoacetate]/[pyruvate][beta-hydroxybutyrate]. If there are no differences in the redox states of the NAD in the two cell compartments the value of the expression is 444 at 37 degrees . The value in the intact rat liver is between 4.7 and 21. 4. alpha-Oxoglutarate or glutamate were still more effective than succinate in maintaining high [beta-hydroxybutyrate]/[acetoacetate] ratios in the homogenates because these substrates supply a reducing agent of NAD(+) and, through succinate, an inhibitor of the oxidation of NADH. 5. When supplemented with alpha-oxoglutarate and EDTA, homogenates readily adjust the redox state of the beta-hydroxybutyrate dehydrogenase system after it has been upset by the addition of either acetoacetate or beta-hydroxybutyrate. 6. Amytal and rotenone raised the value of the [beta-hydroxybutyrate]/[acetoacetate] ratio. This is taken to indicate that the reduction of acetoacetate in the homogenates was not an energy-linked process. 7. 2,4-Dinitrophenol shifted the [beta hydroxybutyrate]/[acetoacetate] ratio in the presence of succinate in favour of oxidation because it inhibited the oxidation of succinate and accelerated the oxidation of NADH. 8. Rotenone increased the rate of ketone-body formation of liver homogenates, though it decreased the rate of oxygen uptake. PMID- 4299128 TI - Microsomal ring-fission of cis- and trans-acenaphthene-1,2-diol. AB - 1. The ring-fission of cis- and trans-acenaphthene-1,2-diol by rat liver microsomes was studied. 2. 1,8-Naphthalic acid was detected and isolated after microsomal incubations of the diols. 3. The accompanying reduction of NAD(+) was followed spectrophotometrically. 4. The optimum pH for the microsomal reaction was 9.4 for the oxidation of the cis-diol and 9.8 for that of the trans-diol. 5. p-Chloromercuribenzoate and 2,4-dichlorophenol inhibited the reaction. 6. Possible mechanisms for the microsomal ring-fission, involving 1,8-naphthalic aldehyde, are discussed. PMID- 4299129 TI - A rapid simple method for the assay of renin in rabbit plasma. AB - 1. EDTA (10mm), 2,3-dimercaptopropan-1-ol (10mm) and chlorhexidine gluconate (0.005%, w/v) cause complete inactivation of plasma enzymes that degrade angiotensin I, but have no effect on the reaction of renin with its substrate. The reagents were termed the selective inhibitors. 2. Thus it is possible to measure renin in plasma by its ability to catalyse the release of angiotensin I. 3. Sterile plasma, treated with the selective inhibitors, is incubated with renin substrate (500-1000ng. of angiotensin content/ml.) at pH6 at 42 degrees for 6hr. 4. Under these conditions the reaction obeys first-order kinetics. Renin activity is calculated in terms of the percentage release of the angiotensin content/hr. 5. As described, the assay is sufficiently sensitive to measure renin in the plasma of all normal rabbits. By extending the length of the incubation, much lower activities can be measured. PMID- 4299130 TI - Properties of renin substrate in rabbit plasma with a note on its assay. AB - 1. Rabbit plasma enzymes that degrade angiotensin I are inhibited completely by the combination of 2,3-dimercaptopropan-1-ol (10mm), EDTA (10mm) and chlorhexidine gluconate (0.005%, w/v). These compounds do not modify the reaction of renin with renin substrate and are termed the selective inhibitors. 2. The renin substrate concentration of plasma can be measured as angiotensin I content by incubating plasma plus the selective inhibitors with renin for a time sufficient to allow complete utilization of renin substrate. 3. This reaction obeys first-order kinetics to substrate concentrations of at least 1000ng. of angiotensin I content/ml. In general, the renin substrate concentrations of normal rabbit plasmas are less than 1000ng. of angiotensin I content/ml. Thus the time required for the complete release of angiotensin I from normal plasma is inversely related to renin activity and is independent of renin substrate concentration. 4. A method for the assay of renin substrate, taking these reaction kinetics into account, is presented. PMID- 4299131 TI - The mechanism of disulphide reduction by mitochondria. AB - 1. Cystamine was reduced to the corresponding thiol by rat liver mitochondria, even in the presence of rotenone or antimycin A. 2. The reduction of disulphides was stimulated by the accumulation of NADH or by the addition of NADH to osmotically ;shocked' mitochondria. 3. Energy made available by oxidative phosphorylation was not essential for the reduction of disulphides. 4. Cystamine was not reduced during the oxidation of NADH by ultrasonically treated particles, which had lost their capacity for oxidation of alpha-oxo acids. 5. In intact mitochondria, arsenite and other inhibitors of vicinal dithiols caused a decrease in the capacity for reduction of disulphides concomitantly with an inhibition of the oxidation of alpha-oxo acids. 6. Isolated lipoamide dehydrogenase reduced cystamine at the expense of NADH, provided that lipoic acid was also present. 7. It is concluded that in mitochondria the reduction of cystamine and related disulphides is probably brought about by interaction with reduced lipoic acid, generated by the alpha-oxo acid dehydrogenase complexes during the oxidation of alpha-oxo acids or by reaction of lipoamide dehydrogenase with NADH. PMID- 4299133 TI - Orf. PMID- 4299132 TI - Inhibition of protein synthesis by an RNA fraction from myeloblastosis virus. PMID- 4299134 TI - A new ultrasensitive method for the determination of proteolytic activity. PMID- 4299135 TI - Light absorption of flavosemiquinone metal chelates. PMID- 4299136 TI - [Correlation of the unspecific permeable mitochondrial space with the "intermembrane space"]. PMID- 4299137 TI - [Kinetic studies of some mechanisms of lactate dehydrogenase with the tritium isotope effect]. PMID- 4299138 TI - Decline and restoration of glycolysis in homogenates from ischemic livers. PMID- 4299139 TI - Adenovirus myocarditis in mice. An electron microscopic study. PMID- 4299140 TI - [Studies on specific partial hydrolysis of sRNA]. PMID- 4299141 TI - [Enzymes of fructose metabolism. Measurement of enzyme activities in the rat kidney]. PMID- 4299142 TI - Induced hypersensitivity to combinations of serotonin and histamine in a strain of mice ordinarily highly resistant to histamine sensitization. PMID- 4299143 TI - Indirect inguinal hernia in congenital rubella. PMID- 4299145 TI - [Considerations on allergic reactions produced by iodized contrast media]. PMID- 4299144 TI - [Contribution to the study of the incidence of drug allergy]. PMID- 4299146 TI - [Unusual reaction after endobronchial administration of lipiodol]. PMID- 4299147 TI - [Vascularization of cerebral tumors. Study by selective peroperative angiography]. PMID- 4299148 TI - Normal growth with subnormal growth-hormone levels. PMID- 4299149 TI - Fluorescent-antibody test for cytomegalovirus macroglobulin. PMID- 4299150 TI - Hypoglycemia and the central nervous system. PMID- 4299151 TI - Acute and subacute neuropathies. PMID- 4299153 TI - [Studies on the activity of certain enzymatic systems in agricultural workers exposed to the action of organophosphorus insecticides]. PMID- 4299152 TI - [Contributions to the viral etiological problem of some acute nephritis cases in children]. PMID- 4299154 TI - Lysosomes and the responses of cells to toxic materials. PMID- 4299155 TI - The release and assay of hormones in the circulation. PMID- 4299156 TI - Choline acetyltransferase: regional distribution in the abdominal ganglion of Aplysia. AB - Using a new microassay, we have determined the properties and the regional distribution of choline acetyltransferase in the abdominal ganglion of Aplysia. Enzyme concentrations in homogenates of groups of cells and in single identified cells indicate that neurons which function as neurosecretory cells, and which do not form chemical synapses with other cells or with peripheral structures, have little or no ability to synthesize acetylcholine; neurons which are involved in visceromotor integrations, and which connect with each other or with the periphery, have a substantial concentration of the enzyme. PMID- 4299157 TI - [A comparative study of mouse leukemia viruses by the transplantation resistance method]. PMID- 4299158 TI - [On the value of chloroquine in the treatment of malignant tumor diseases]. PMID- 4299159 TI - [Therapy results and prognosis of stomach cancer]. PMID- 4299160 TI - Induction of sorbitol dehydrogenase by sorbitol in Aspergillus niger. PMID- 4299161 TI - [Preliminary study of a strain of Herpesvirus bovis isolated in a pneumonic lesion in a calf]. PMID- 4299162 TI - [The infectious diseases of the respiratory organs in chickens]. PMID- 4299163 TI - [Report on 5 years of cancer registrations (1954-1958) in malignant neoplasms of the nose and its sinuses]. PMID- 4299164 TI - The adrenal cortex. I. Historical aspects. II. Clinical considerations. PMID- 4299165 TI - [Recent acquisitions on neurogenic amyotrophy in the pediatric age. Description of a case of early juvenile neurogenic amyotrophy (Graveleau type?)]. PMID- 4299166 TI - [Tumors in childhood (clinico-statistical considerations)]. PMID- 4299167 TI - [Tumors in the newborn]. PMID- 4299168 TI - [Primary intrathoracic tumors in children]. PMID- 4299169 TI - [Tumors of the urinary tract in children]. PMID- 4299171 TI - [2 cases of hyperinsulinism caused by beta islet cell adenoma]. PMID- 4299170 TI - Diminished effect of sympathetic nerve stimulation in cats pretreated with 5 hydroxydopa; formation and liberation of false adrenergic transmitters. PMID- 4299172 TI - [Calcitonin (physiological data)]. PMID- 4299173 TI - [Exploration of the thyrocalcitonin function in thyropathies by the induced hypercalcemia test]. PMID- 4299174 TI - [Preliminary trial of classification of the syndromes of thyrocalcitonin hyper hyposecretion]. PMID- 4299175 TI - [Study of disorders of glycoregulation in the course of chronic hepatopathies of alcoholic origin]. PMID- 4299177 TI - [Current bacteriologic and epidemiological aspects of Salmonelloses (apropos of 536 Salmonella strains isolated in Lorraine)]. PMID- 4299176 TI - [The Achilles reflexogram and its changes induced by vitamin B 12 in obesity]. PMID- 4299178 TI - [Cystoadenomas and cystoadencarcinomas of the pancreas]. PMID- 4299179 TI - [Biological and clinical study of diffuse atrophy of the small intestine]. PMID- 4299180 TI - [Anatomo-pathologic study of 7 cases of diffuse atrophy of the small intestine]. PMID- 4299181 TI - [Immediate action of Aix thermal operations on some elements of circulating blood in rheumatism patients]. PMID- 4299182 TI - [A new antibiotic in the treatment of infections caused by gram positive bacteria: lincomycin. In vitro study and clinical experience]. PMID- 4299183 TI - [Sulfurous acid and its salts in food processing and storage. A review of literature]. PMID- 4299184 TI - [The ultrastructure of pseudomucinous ovarian cystomas]. PMID- 4299185 TI - [Experimental in-vitro studies on double bacterial and viral infection per vaginam]. PMID- 4299186 TI - The 7H11 medium for the cultivation of mycobacteria. PMID- 4299187 TI - Vasopressin in the evaluation of pituitary-adrenal function. PMID- 4299188 TI - The circulating lymphocyte--its role in infectious mononucleosis. PMID- 4299189 TI - Immunohistochemical identification of actomyosin in myoepithelium of human tissues. PMID- 4299190 TI - The effects of vitamin D2 and dietary phosphorus on oxidative enzymes in the epiphyseal cartilage of rachitic rats. A histochemical study. PMID- 4299191 TI - Acute tibial pain. PMID- 4299193 TI - Morphologic and biochemical studies of dog heart mitochondria after short periods of ischemia. PMID- 4299194 TI - Histochemical study of effects of hypoxia and isoproterenol on rat myocardium. PMID- 4299192 TI - Hepatoma following carbon tetrachloride poisoning. PMID- 4299195 TI - Cholangiocarcinoma causing hypercalcemia and hypophosphatemia without skeletal metastases (pseudohyperparathyroidism). PMID- 4299197 TI - Studies of enzyme activities in uterine and ovarian tumours. 3. A comparison of enzyme activity in patient's serum with the enzyme activity of the fluids in different cystic ovarian tumours. PMID- 4299198 TI - [Chromatography of oleandomycin in thin layer on silica gel]. PMID- 4299196 TI - [Acquired hemolytic anemias]. PMID- 4299199 TI - [Antiviral effect of RNA in mice and in tissue culture]. PMID- 4299200 TI - [Isolation and properties of lecithinase from Clostridium perfringens]. PMID- 4299201 TI - [On the role of the lipid component of kinasine in its specific stimulating action upon glycolysis]. PMID- 4299203 TI - Heterogeneity in the ability of rabbit 7S and 19S neutralizing antibodies to differentiate between intratypic antigenic variants of Herpes simplex virus. PMID- 4299202 TI - Pathological findings after long-term sulfonylurea therapy. PMID- 4299205 TI - Further investigation of histochemistry of fructose-1,6-diphosphate D glyceraldehyde-3-phosphate-lyase in the rat brain. PMID- 4299204 TI - Electron microscopic observations of the interaction of macrophages and lymphocytes in a virus-induced murine lymphoma. PMID- 4299206 TI - Primary carcinoma of the liver in east Pakistan. PMID- 4299207 TI - [Pathogenesis and industrial hygiene of silicosis]. PMID- 4299208 TI - Infections in recipients of liver homografts. PMID- 4299209 TI - Treatment and prevention of rheumatic fever and rheumatic heart disease. PMID- 4299210 TI - Isolation of a bovine rhinovirus. PMID- 4299211 TI - Studies on hepatic glycolytic enzymes of normal and scorbutic guinea pigs administered acetoacetate. PMID- 4299212 TI - [On the importance of molecular configuration for the development of radiation injury]. PMID- 4299213 TI - [Stabilization of vitamin preparations. II. Syrup of vitamin D3 and its stabilization]. PMID- 4299214 TI - [Treatment, by controlled ionokinesis, of chronic coronary insufficiency and arteriopathies of the lower extremities]. PMID- 4299215 TI - Transmission in sympathetic ganglia. PMID- 4299216 TI - Mechanism of diazoxide hyperglycemia in animals. PMID- 4299217 TI - Biochemical aspects of the hyperglycemic action of diazoxide. PMID- 4299218 TI - The effects of diazoxide and benzothiadiazine diuretics upon phosphodiesterase. PMID- 4299220 TI - Inhibition of insulin release by diazoxide and its relation to catecholamine effects in man. PMID- 4299219 TI - Further studies on diazoxide suppression of insulin release from abnormal and normal islet tissue in man. PMID- 4299221 TI - Studies on diazoxide-induced hyperglycemia: an extrapancreatic mechanism. PMID- 4299223 TI - Metabolic effects of diazoxide in normal subjects, patients with diabetes mellitus, and patients with organic hypoglycemia. PMID- 4299222 TI - Clinical use of diazoxide and studies of the mechanism of its hyperglycemic effects in man. PMID- 4299224 TI - The therapeutic application of diazoxide in pediatric hypoglycemic states. PMID- 4299225 TI - Clinical experience with diazoxide. PMID- 4299226 TI - Control of hypoglycemia with diazoxide and hormones. PMID- 4299228 TI - Lipid chemistry and metabolism. PMID- 4299227 TI - Clinical and physiologic studies using diazoxide in the treatment of hypoglycemia. PMID- 4299229 TI - Isolation of cytomegalovirus from the blood leucocytes of a patient with post transfusion mononucleosis. PMID- 4299230 TI - Clinical, physiological and pathological observations in a case of progressive autonomic nervous system degeneration associated with Holmes-Adie syndrome and peripheral neuropathy. PMID- 4299231 TI - Antibodies to reoviruses, parainfluenza 3 virus, encephalomyocarditis virus and infectious bovine rhinotracheitis virus in porcine serums. PMID- 4299232 TI - Oxidation-reduction properties of the mitochondrial flavoprotein chain. PMID- 4299233 TI - Enzyme localization in the inner and outer membranes of rat liver mitochondria. PMID- 4299234 TI - [Study of radical stages of low-temperature radiolysis of some heteroaromatic compounds-components of nucleic acids]. PMID- 4299235 TI - [Kinetic regularities of changes in free radical content during malignant growth and action of inhibitors of radical processes]. PMID- 4299236 TI - [ESR analysis of x-ray primary effect on wheat seeds]. PMID- 4299238 TI - [On the possibility of explaning the protective action of polyanions and cysteine in radiolysis by a mechanism of energy transfer]. PMID- 4299237 TI - [Formation of free radical states under the action of visible light on chlorophyll containing systems]. PMID- 4299240 TI - [Semiquinoid free radicals in mitochondrial respiration and phosphorylation]. PMID- 4299239 TI - [Oxidation of NAD-H2 by subcellular fractions with participation of peroxidase and oxygen]. PMID- 4299241 TI - [Structural analysis of lecithins by thin-layer chromatography]. PMID- 4299243 TI - Meningioma of the optic nerve. PMID- 4299244 TI - The hypophyseal-adrenocortical response to various different stressing procedures in ACTH-treated rats. PMID- 4299242 TI - [Purification of enzyme complex of malate- and NAD-H2-dehydrogenases from membranes of Micrococcus lysodeikticus]. PMID- 4299245 TI - Effects of substrates and hormones on glycogen content of the mouse hemidiaphragm in vitro. PMID- 4299246 TI - The influence of norethindrone and mestranol on pituitary-adrenal function. PMID- 4299247 TI - On the viral etiology of epidermodysplasia verruciformis Lewandowsky-Lutz. Electron microscope studies. PMID- 4299248 TI - [Anterior pituitary gland insufficiency in sarcoidosis]. PMID- 4299249 TI - Chromosome breakage induced by a carcinogenic hydrocarbon in Chinese hamster cells and human leukocytes in vitro. PMID- 4299251 TI - Oral polio immunization of the newborn infant; a possible method for overcoming interference by ingested antibodies. PMID- 4299250 TI - Aortography in children with abdominal masses. PMID- 4299252 TI - [Inzellen--hypertensin in the treatment of severe shock]. PMID- 4299253 TI - [Unusual cause of bilateral paralysis of the anterior tibial muscle]. PMID- 4299254 TI - Changes in structure of human bone with age. PMID- 4299255 TI - Isolation of a receptor complex for a tumor specific agglutinin from the neoplastic cell surface. PMID- 4299256 TI - Antiviral properties of 1-phenoxymethyl-3,4-dihydro and 1,2,3,4 tetrahydroisoquinolines. PMID- 4299257 TI - Radiation enhancement of SV40 transformation in 3T3 and human cells. PMID- 4299258 TI - Evidence of infection with influenza viruses in migratory waterfowl. PMID- 4299259 TI - [A radioimmunological determination of angiotensin]. PMID- 4299260 TI - [The juxtaglomerular apparatus and renin secretion in experimental arterial hypertension]. PMID- 4299261 TI - [The physiological relationship between the renin-angiotensin system and aldosterone]. PMID- 4299262 TI - [Sodium in experimental hypertension]. PMID- 4299263 TI - [Renin and aldosterone in human arterial hypertension (excluding Conn's syndrome)]. PMID- 4299264 TI - Specific cleavage of viral proteins as steps in the synthesis and maturation of enteroviruses. PMID- 4299265 TI - Spin-labeled hemoglobin derivatives in solution and in single crystals. PMID- 4299266 TI - Hydrogen-addition radicals formed in the aromatic rings of amino acids, polyamino acids, and proteins. PMID- 4299267 TI - Prompt stimulation of the organic binding of iodine in the thyroid by adenosine 3',5'-phosphate in vivo. PMID- 4299268 TI - Localization of nucleotide phosphohydrolase activity within vaccinia. PMID- 4299269 TI - A method for determining the fraction of the viral genome transcribed during infection and its application to adenovirus-infected cells. PMID- 4299270 TI - [Peripheral nerve diseases of vascular origin]. PMID- 4299271 TI - [Results of therapy of the immunodepressive type in 40 patients with severe rheumatoid polyarthritis]. PMID- 4299272 TI - [Influence of endocrinohormonal factors on viruses and on clinical and experimental viral diseases]. PMID- 4299273 TI - [Use of type specific serum for differentiation of the rates of adsorption, on cultured cell receptors, of several strains of enteroviruses (polio 3, ECHO 1 and 7, Coxsackie A 9, B 1 and B 5)]. PMID- 4299274 TI - In vitro assembly of poliovirus-related particles. PMID- 4299275 TI - [The renal response to angiotensin during pregnancy and the puerperium in subjects with gestosic syndromes]. PMID- 4299276 TI - [Carcinosarcoma of the uterus with unusual histological differentiation]. PMID- 4299277 TI - [Estimation of serum levels of endogenous angiotensin by the infusion test of exogenous agniotensin]. PMID- 4299278 TI - [Studies on the isolation and characterization of equine influenza virus]. PMID- 4299279 TI - [Functional after-care of surgically managed fractures of the hip and femur]. PMID- 4299280 TI - [Fractionation of rat liver microsomes. I. Biochemical characteristics and enzymatic activities of the subfractions obtained on density gradient]. PMID- 4299281 TI - [Nuclear phospholipids of rat liver in compensatory hypertrophy]. PMID- 4299282 TI - [Histologic images in pumiced and non-pumiced burn patients in Africa]. PMID- 4299283 TI - [Treatment of experimental amebiasis in rats with niridazole]. PMID- 4299284 TI - Automated procedure for serum aldolase estimation. Fructose-1, 6-diphosphatase and fructose-1-phosphatase. PMID- 4299285 TI - Optimum reaction conditions for human lactate dehydrogenase isoenzymes as they affect total lactate dehydrogenase activity. PMID- 4299286 TI - A comparison of reduced-NAD preparations from four commercial sources. PMID- 4299287 TI - [The protracted clinical course of hepatitis in ambulatory after care of hepatitis]. PMID- 4299290 TI - [On the problem of the etiology of infectious hepatitis]. PMID- 4299289 TI - [ACTH in the therapy of infantile epilepsy]. PMID- 4299288 TI - [Possible alternative to the corticoid treatment of hyperandrogenic endocrine diseases with ovulation inhibitors]. PMID- 4299291 TI - Endolymphatic infusion of I-131 in the treatment of malignant melanoma: early experiences. PMID- 4299292 TI - Treatment of alcoholism. PMID- 4299293 TI - [The anatomo-pathologic consequences of abdominal irradiations]. PMID- 4299294 TI - [Clinical forms, development and medical treatment of actinic intestinal lesions. (Ano-rectitis and recto-sigmoiditis, colonic or small intestinal lesions post curie and radiotherapy possibilities in the course of treatment of cancers of the uterine cervix and other rarer abdominal lesions)]. PMID- 4299295 TI - [The radiologic diagnosis of actinic lesions of the intestine]. PMID- 4299297 TI - [The surgical treatment of actinic lesions of the intestine]. PMID- 4299296 TI - [The prevention of digestive radiolesions]. PMID- 4299298 TI - [The concentration of histamine in the blood and in the gastric juice in patients with gastric or duodenal ulcer]. PMID- 4299299 TI - [Histological and histochemical characteristics of oncogenic (Hurthle cell) carcinoma of the thyroid gland and its lung metastases]. PMID- 4299300 TI - [On the clinical picture of organic isthmoplegias]. PMID- 4299301 TI - [Primary adenocarcinoma of the vulva (hidradenocarcinoma vulvae)]. PMID- 4299303 TI - [A case of disseminated reticulo-nodular form of pulmonary alveolar cancer]. PMID- 4299302 TI - [Surgical risk in elderly women]. PMID- 4299304 TI - [Platelets and viruses]. PMID- 4299305 TI - [Bronchial adenomas]. PMID- 4299306 TI - [Glomus tumors of the stomach]. PMID- 4299307 TI - [On pseudo-vascular initial symptoms of intracranial expansive processes]. PMID- 4299309 TI - [Evaluation of the usefulness of roentgenological examination in the diagnosis of neoplastic abdominal tumors]. PMID- 4299308 TI - [Peripheral nerve diseases in chronic hypoglycemic states]. PMID- 4299310 TI - [Surgical treatment of insulinoma]. PMID- 4299311 TI - [Histoclinical interpretation of benign synovioma with malignant course]. PMID- 4299313 TI - [A case of poxvirus infection in a cow milker]. PMID- 4299314 TI - [Pseudodiphtheritic conjunctivitis caused by type 3 Adenovirus]. PMID- 4299312 TI - [Virologic examinations of sewage]. PMID- 4299316 TI - [Free radicals in irradiated fatty acids]. PMID- 4299315 TI - [Effect of mass oral preventive vaccination on the epidemiological situation of poliomyelitis in Poland]. PMID- 4299317 TI - [Aldosteronuria in the hypertensive patient with Addison's disease]. PMID- 4299318 TI - [Leukoconcentration method in malignant neoplasms]. PMID- 4299319 TI - [Sex chromatin content in parenchymal and stromal cells of malignant breast tumors]. PMID- 4299320 TI - [The status of the central and peripheral nervous systems in patients with a history of tetanus]. PMID- 4299321 TI - [The effect of biologically active components of Transcarpathian mineral water on intestinal enzyme activity]. PMID- 4299322 TI - [On idopathic orthostatic hypotension of the "gravitational" type. Remarks from observed case]. PMID- 4299323 TI - [On therapeutic procedure following intervertebral disk surgery]. PMID- 4299324 TI - [Chemical uniformity of polymyxin M]. PMID- 4299325 TI - [Effect of antibiotic 255 on some viruses]. PMID- 4299326 TI - [Use of amino acids and pathogenic and non-pathogenic E. coli with increased resistance to a number of antibiotics in experiments in vitro and in the process of treatment of patients with colienteritis]. PMID- 4299327 TI - [Effect of interferon on the dynamics of antibody formation in chickens in avian pseudopest]. PMID- 4299328 TI - [Preliminary results of clinical trial of the antineoplastic antibiotic bruneomycin]. PMID- 4299329 TI - Peripheral neuropathy associated with disulfiram (Antabuse) therapy. PMID- 4299330 TI - [A case of thecoma of the ovary in a pregnant woman]. PMID- 4299331 TI - Abortion in a dairy herd vaccinated for infectious bovine rhinotracheitis. PMID- 4299332 TI - Bluetongue disease in cattle. PMID- 4299333 TI - [On the thin-layer chromatographic separation and identification of tuberculostatic antibiotics]. PMID- 4299334 TI - The quantitative thin layer chromatography of corticosteroids. PMID- 4299336 TI - [Focus of adenovirus infection in a nursery in the city of Bucharest]. PMID- 4299335 TI - Effect of intake of copper, molybdenum and sulphate on copper metabolism in sheep. II. Copper status of the newborn lamb. PMID- 4299337 TI - [Observations on the nuclear morphology of some strains of Entamoeba dysenteriae isolated in Rumania]. PMID- 4299338 TI - [Salivary gland tumors. II]. PMID- 4299339 TI - [Pseudosarcoma of the larynx coexistent with epithelial paratypia]. PMID- 4299340 TI - [Contribution to case reports on tongue adenomas, originating from salivary glands]. PMID- 4299341 TI - [Treatment of special types of breast cancer]. PMID- 4299342 TI - [Results of treatment of breast cancer Paget's type]. PMID- 4299343 TI - [Unusual coincidence of mixed tumor and sarcoidosis of the parotid gland]. PMID- 4299344 TI - [Behavior of the kallikrein-bradykinin system in the course of blood pressure increases]. PMID- 4299345 TI - [The responsibility of the psychiatrist in early dismissals]. PMID- 4299346 TI - [Carcinogenic alkylating substances. II. Bis-(morpholino-)methane]. PMID- 4299347 TI - On the effects of blastomogenic substances on the organism during embryogenesis. PMID- 4299348 TI - Induction of nephroblastomas in the rat with dimethylnitrosamine. PMID- 4299349 TI - [In vivo studies on the effect of Trenimon (I). Changes of biochemical parameters and inhibition of cell proliferation of Ehrlich ascites tumor cells]. PMID- 4299350 TI - [On the nomenclature and pathogenesis of salivary gland tumors]. PMID- 4299351 TI - Steroid determinations in six cases of hyperplasia and three cases of tumour of the adrenal cortex. PMID- 4299352 TI - Latency time, maximal amplitude and electromyography in diabetic patients. PMID- 4299353 TI - [Prolactin adenoma in a irl whose mother had had a pituitary adenoma with amenorrhea-galactorrhea]. PMID- 4299355 TI - Pathogenesis of monkey pox. PMID- 4299354 TI - Bactericidal activity of mouse lung in reovirus infection. PMID- 4299356 TI - Factors modifying host resistance to viral infection. I. Effect of immunosuppressive drugs on experimental infection of mice with encephalomyocarditis virus. PMID- 4299357 TI - Effect of 6,9-diamino-2-ethoxyacridine on bacteriophages and animal viruses. PMID- 4299358 TI - Inhibition of replication of herpes simplex and vaccinia viruses in vitro by Escherichia coli and lipopolysaccharide. PMID- 4299359 TI - Phosphoinositides of Corynebacterium xerosis. PMID- 4299360 TI - [Properties of NAD-kinase from pigeon liver]. PMID- 4299361 TI - [The effects of various chemical compounds on the lecithinase of C1. perfringens]. PMID- 4299362 TI - [Reversed electron transfer and parallel changes in the SH-group content of mitochondria after addition of cysteine]. PMID- 4299363 TI - [Polarimetric studies of the conformational changes in D-glyceric aldehyde-3 phosphate dehydrogenase]. PMID- 4299364 TI - [Action of spleen and venom phosphodiesterases in transfer-RNA acetylated at the 2 ribose hydroxyl]. PMID- 4299365 TI - [Fractionation of apyrase from Mimosa pudica leaves into ADPase and Mn++ activated ATPase]. PMID- 4299367 TI - Comparative studies on the histological picture of lesions in chick chorio allantoic membranes infected with vaccinia, smallpox and alastrim viruses. PMID- 4299366 TI - [The isolation and properties of Clostridium perfringens collagenase]. PMID- 4299368 TI - [The serum cerebrospinal fluid enzyme levels in acute cerebral circulatory accident]. PMID- 4299369 TI - Chromosome analysis of Rous tumours in the rabbit. PMID- 4299371 TI - Continuous determination of the clearance of 131-I-diatrizoate, an inulin substitute. PMID- 4299370 TI - Mechanism of enhancement of eccrine sweating by localized heating. PMID- 4299373 TI - Isoelectric analysis of cytolytic bacterial proteins. PMID- 4299372 TI - Bordetella pertussis-induced alteration of the normal hyperglycemic response of mice to 3',5'-adenosine phosphate. AB - Blockade of the adrenergic receptors or the injection of Bordetella pertussis vaccine prevented the normal hyperglycemic response of CFW mice to exogenous cyclic 3',5'-adenosine phosphate (3',5'-AMP). The cyclic nucleotide was also ineffective in offsetting the histamine hypersensitivity of the beta adrenergically blocked and the pertussis-sensitized groups. These observations suggest that the autonomic malfunction occurs at a point(s) subsequent to release of 3',5'-AMP. Neither the hyperglycemic effect of epinephrine or 3',5'-AMP, or both, nor the histamine sensitivity of pertussis-pretreated animals was influenced by the subcutaneous administration of theophylline. PMID- 4299375 TI - Fine structure of laminaran of Eisenia bicyclis. PMID- 4299374 TI - Action mechanism of phenothiazine derivatives on mitochondrial respiration. PMID- 4299376 TI - Oxidative phosphorylation in Micrococcus denitrificans. IV. Further characterization of electron-transfer pathway and phosphorylation activity in NADH oxidation. PMID- 4299377 TI - Oxidative phosphorylation in Micrococcus denitrificans. V. Effects of iron deficiency on respiratory components and oxidative phosphorylation. PMID- 4299379 TI - The primary structure of valine-I transfer ribonucleic acid from Torulopsis utilis. PMID- 4299380 TI - Nasolabial cysts: report of two cases. PMID- 4299381 TI - Sebaceous gland adenoma of the buccal mucosa: report of case. PMID- 4299378 TI - Studies on erythrocyte glycolysis. VII. Changes of glycolytic intermediates in erythrocytes during storage in acid-citrate-dextrose medium. PMID- 4299382 TI - Auriculotemporal syndrome after injection into the temporomandibular joint: report of case. PMID- 4299383 TI - [Histopathology of the Wilm's tumor. Comparison with histogenesis of the kidney]. PMID- 4299384 TI - [Case of juvenile primary hepatoma]. PMID- 4299385 TI - [Bizarre leiomyoblastoma of the small intestine]. PMID- 4299386 TI - [Determination of antibody titer and its response to therapy prior to using technics with greater risk in perinatal hemolytic disease]. PMID- 4299387 TI - A method for the propagation of large amounts of Rous sarcoma virus. PMID- 4299388 TI - Focus formation by murine sarcoma virus: enhancement by DEAE-dextran. PMID- 4299389 TI - Structure of simian virus 40. IV. The polypeptide chains of the virus particle. PMID- 4299390 TI - Evidence for differences in size and composition of the poliovirus-specific polypeptides in infected HeLa cells. PMID- 4299391 TI - Proteins of Rous sarcoma virus. PMID- 4299392 TI - [On the problem of antibiotic combinations in Pseudomonas aeruginosa in vitro]. PMID- 4299393 TI - [Cytogenetic studies of ascites hepatoma in the rat after several years of heterologous growth in hamsters]. PMID- 4299394 TI - [Immunological properties of Graffi virus-induced leukemias of the AKR mouse strain]. PMID- 4299395 TI - [Extreme hyperthermia studies on 4 different tumors in rats]. PMID- 4299396 TI - [Diaplacentally induced kidney tumors in the rat]. PMID- 4299397 TI - Metabolism and mechanism of action of estrogens. IX. Metabolism of estrone by microsomes from rat liver and transplanted hepatocellular carcinomas including minimal deviation (Morris 5123 C, 7800, 9121) hepatomas. PMID- 4299398 TI - [On the problem of the cusative relation between the inhibition of glycolysis and the cystostatic effect of trenimon]. PMID- 4299399 TI - [Spontaneous mutations in acetic acid bacteria. I. Mutations in antibiotic resistance]. PMID- 4299400 TI - [The problem of inclusion bodies in neoplasms. II. In man]. PMID- 4299401 TI - [Detection of a membrane antigen in the polyoma-- hamster neoplasm system]. PMID- 4299402 TI - [Embryonal sarcoma. Karyotype study of 7 cases]. PMID- 4299403 TI - [Neoplasms on bladder exstrophy]. PMID- 4299404 TI - [On the effect of ouabain on the metabolism of bovine and calf lenses]. PMID- 4299405 TI - [Synthesis and incorporation of a 14C-and 3H-labeled 4-dimethylallyl-tryptophan and a 14C-labeled 4-dimethylallyl-tryptamine as well as incorporation of a 14C labelled Dimethylallyl-pyrophosphate]. PMID- 4299406 TI - [Studies on the reactivity of macrophages to enterovirus infections. I. Effect of phytohemagglutinin on macrophage cultures]. PMID- 4299407 TI - [Studies on the reactivity of macrophages to enterovirus infections. II. Macrophage culture reaction to the virus introduction]. PMID- 4299408 TI - [Studies on the reactivity of macrophages to enterovirus infections. 3. Reproduction of wild, attenuated and intermediate strains of Poliomyelitis virus in macrophage culture]. PMID- 4299409 TI - [The adrenal response to prolonged treatment with corticotropin]. PMID- 4299410 TI - [Behavior of serum phosphatase during viral hepatitis]. PMID- 4299411 TI - Action of angiotensin in normal, adrenalectomized, and renal hypertensive trained dogs. PMID- 4299412 TI - [A case of hepatoma in a child treated by left-sided hepatolobectomy]. PMID- 4299413 TI - [Results of treatment of myocardial infarction associated with shock in relation to the kind of administered drugs]. PMID- 4299414 TI - [Chorioepitheliosis]. PMID- 4299415 TI - [Penetrating mole: pulmonary metastasis. Maternal death by amethopterin]. PMID- 4299416 TI - A myxovirus isolated from a case of infectious hepatitis. PMID- 4299417 TI - [Waldenstrom's disease. Rheumatologic manifestations]. PMID- 4299418 TI - [Intravenous tolbutamide test in secondary failure of antidiabetic sulfonamides]. PMID- 4299419 TI - [Meteorological factors and acute cerebral vascular accidents]. PMID- 4299420 TI - [Single and chronic intrapulmonary round shadows]. PMID- 4299421 TI - [Study of the fixation and metabolism of arginine aspartate by the radioisotope method]. PMID- 4299422 TI - [Tumors of the thymus. Apropos of surgical statistics in 103 cases]. PMID- 4299423 TI - [Mucoviscidosis in adults]. PMID- 4299424 TI - [Chyloperitoneum and bilateral elephantiasis]. PMID- 4299425 TI - [Apropos of a case of surgical removal of pulmonary angioma in an infant]. PMID- 4299426 TI - [Headache, asymmetrical orbito-ocular insertion and transverse dislocation of the atlanto-occipital joint]. PMID- 4299427 TI - [Apropos of hepatic hamartoma]. PMID- 4299428 TI - [Rectal tuberculosis: a now rare diagnostic pitfall]. PMID- 4299430 TI - [Diagnostic possibilities of perfusion cholecystocholangiography]. PMID- 4299429 TI - [Different response of the superficial and deep lymph nodes to therapy in malignant lymphoreticulopathies]. PMID- 4299431 TI - [Contribution on the clinical aspects of infantile mediastinal tumors: analysis of 59 clinical cases]. PMID- 4299432 TI - [Steroid hormones in the menopause. Case report contribution to the therapeutic problem of climacteric psychoses with sex hormones]. PMID- 4299433 TI - [The effect of catecholamine, hypertensin and vasopressin injections on the liver circulation in dogs]. PMID- 4299434 TI - [Studies on the oncogenic transformation of hamster kidney cells in vitro using the simian virus SV 40]. PMID- 4299435 TI - Hydrolitic enzymes in cells of the prostate gland and seminal vesicles of castrated white rats. PMID- 4299436 TI - [The excretory function of oncocytes. Cytologic, karyometric and enzyme histochemical studies]. PMID- 4299437 TI - [Elaboration of type B viral particles in the thymus of the mouse. Electron microscopical study]. PMID- 4299438 TI - [Infection of ischemic tissue with gas gangrene bacillus]. PMID- 4299440 TI - [Neonatal discovery of hypophosphatasia. Bone improvement. Fatal convulsant encephalopathy]. PMID- 4299439 TI - [Enzyme histochemical studies of mechanically induced hydronephrosis in rabbits]. PMID- 4299441 TI - [Hormonal treatment of 58 cases of infantile spasms. Results and long-term psychological prognosis]. PMID- 4299442 TI - [Experimental studies os syncarcinogenesis in esophageal carcinoma]. PMID- 4299443 TI - [The evaluation of the incidence of bronchial and stomach carcinomas in the autopsy material of the 1st Pathologisch-anatomisches Institut zu Brno]. PMID- 4299444 TI - [Immunologic cross experiments with o-aminoazotoluene hepatomas and a spontaneous liver tumor in mice]. PMID- 4299445 TI - [Cytologic and cytochemical characterization of a Graffi virus-infected Gross leukemia and its cell clones]. PMID- 4299446 TI - [Enzymatic and chemical characterization of isolated hepatocytes]. PMID- 4299447 TI - [Study of the triglycerides of lymphatic chylomicrons separated by silica gel chromatography impregnated with silver nitrate: evidence of endogenous origin of triglycerides]. PMID- 4299448 TI - [Test of the pharyngeal curette in the study of carriers of aphthae virus]. PMID- 4299449 TI - [Mixed tumor of the nasal septum]. PMID- 4299450 TI - [Spectrophotometric determination of riboflavin based on quantitative photoreduction]. PMID- 4299451 TI - [Eye manifestations in lesions of the corpus callosum]. PMID- 4299452 TI - [Functional status of the adrenal cortex in berylliosis]. PMID- 4299453 TI - [Plasma insulin, glucagon and somatotropin in 4 cases of hypoglycemia due to Langerhansian adenoma]. PMID- 4299454 TI - [Unusual fluctuation of insulin requirements in eosinophilic hypophyseal adenoma (diabetic acromegaly)]. PMID- 4299456 TI - Fine structural changes in rat liver cells in response to prolonged thioacetamide. PMID- 4299455 TI - [Insulin producing and non-insulin producing pancreatic tumors with endocrine disease features]. PMID- 4299457 TI - [Treatment of pain from the neurosurgical viewpoint]. PMID- 4299458 TI - Renin and angiotensin in health and disease. PMID- 4299459 TI - [Secondary hyperaldosteronism]. PMID- 4299460 TI - [Contribution on double formation of the esophagus in the neck region]. PMID- 4299461 TI - [Functional study of the Kultchitzky-Masson cell system by the induced serotonin test in gastrectomized patients. Its value in the dumping syndrome]. PMID- 4299463 TI - [Contraception in France. Survey of 10 years activity and perspectives for the future]. PMID- 4299462 TI - [Pleural effusion and chronic pancreatopathies. (Apropos of 7 cases)]. PMID- 4299464 TI - [Surgical treatment of heart diseases of newborns]. PMID- 4299465 TI - [Clinical and biological study of the application of alpha-tocopheryl-quinone for 5 years of primary and secondary muscular diseases and for 1 case of scleroderma]. PMID- 4299466 TI - [Results of conventional radiotherapy of glioblastomas]. PMID- 4299468 TI - [On the implantation of ascites tumor cells into the peritoneum]. PMID- 4299467 TI - [Bronchial adenoma (clinical picture, diagnosis and surgical treatment)]. PMID- 4299469 TI - [Arrhenoblastoma of the ovaries (2 case reports)]. PMID- 4299470 TI - [Malignant arrhenoblastoma of the ovary (a case report)]. PMID- 4299471 TI - [Studies on a lipolytic substance isolated from porcine hypophyses (fraction H). Extraction and purification of the lipolytic fraction]. PMID- 4299472 TI - [The reactivity of the adrenal cortex in various domestic species under normal and pathological conditions (experimental and clinical observations)]. PMID- 4299473 TI - [Metastatic mammary tumors in the dog. II. Clinico-pathological studies on mammary sarcoma and carcino-sarcoma]. PMID- 4299474 TI - [The development of petechial hemorrhages on the under-surface of the tongue in the horse and its relation to infection with the virus of equine infectious anemia]. PMID- 4299475 TI - [Derivatives of viomycin. I. Preparation and properties of viomycin nicotinate and isonicotinate]. PMID- 4299476 TI - [Derivatives of viomycin. II. Preparation and properties of some viomycin penicillinates]. PMID- 4299477 TI - [Stabilization of vitamin drugs. 3. Effect of sterilization on the stability of injectible solutions of vitamin D 3]. PMID- 4299478 TI - [Phosphatase activity of mycobacteria]. PMID- 4299479 TI - [Study of the relations between the tumorigenic virus of quail and Rous sarcoma virus]. PMID- 4299480 TI - [Experimental studies on animals on the use of pyrrolidino-methyl-tetracycline and penicillin G on the prophylaxis and therapy of gas gangrene]. PMID- 4299481 TI - [On the problem of the toxic effect of trivalent antimony preparations]. PMID- 4299482 TI - The influence of reserpine on the inhibition of ACTH-secretion induced by exogenous ACTH or a corticoid injection. PMID- 4299483 TI - [Studies of the etiopathogenesis of contact eczemas. 2. Chromate allergy and contact eczema. On the nature and frequency of casual relations and aspects of the corresponding clinical picture]. PMID- 4299484 TI - [On tumors of heterotipic mammary rudiments]. PMID- 4299486 TI - [Observations on a case of acrocephalo-syndactyly with special reference to the oro-facial picture]. PMID- 4299487 TI - [Cylindromas of the maxilla]. PMID- 4299488 TI - [On a case of hepatoma]. PMID- 4299485 TI - [Histochemical and biochemical studies of a pancreatic tumor in a patient with Zollinger-Ellison syndrome]. PMID- 4299490 TI - [Preserved tissue for use in the tropics]. PMID- 4299489 TI - [Problems posed by the control of products containing several antibiotics]. PMID- 4299491 TI - [Psoriatic polyarthritis and amyloidosis]. PMID- 4299492 TI - [Essential myasthenia gravis and myastheniform syndromes]. PMID- 4299493 TI - [Biology of the intervertebral disk]. PMID- 4299494 TI - [The genetic risk of oral contraceptive products]. PMID- 4299495 TI - [Polypoid mucosecreting adenocarcinoma of the cecum of the "pseudo-appendicular" form in a young boy of 14]. PMID- 4299496 TI - [Anteposition of the ulnar nerve]. PMID- 4299497 TI - [The effect of hydrocortisone and insulin on glucoso-6-phosphatase activity in rat kidney]. PMID- 4299498 TI - [Interaction of heparin with polymyxin M and streptomycin]. PMID- 4299499 TI - [Studies of glutamate dehydrogenase activity in normal tissues and in malignant tumors]. PMID- 4299500 TI - [Reversible suppression of electron transfer between cytochromes B and C]. PMID- 4299501 TI - [Inhibition of protein and nucleic acid biosynthesis by phenol compounds in vivo experiments]. PMID- 4299502 TI - [Effect of aminazine on the activity of oxidative enzymes in the motor analyzer of the cat brain]. PMID- 4299503 TI - [Mechanism of deamination of some L-amino acids in malignant tumors]. PMID- 4299504 TI - [Enzymatic transformation of NAD in cellular fractions of normal and denervate skeletal muscles]. PMID- 4299505 TI - [Changes in the extent of the crabtree effect in ascitic lymphoma NK/ly induced by hydrocortisone]. PMID- 4299506 TI - [Quantitative determination of the nucleic acids in isolated cell nuclei of the thymus]. PMID- 4299507 TI - [Comparative studies on the effect of monosaccharides and hormones on insulin secretion of isolated pancreatic tissue of various mammals and frogs]. PMID- 4299508 TI - Combination of potassium perchlorate and propylthiouracil in the treatment of thyrotoxicosis. PMID- 4299509 TI - A correlative study of endocrine rhythms in rats. PMID- 4299510 TI - Isolation of inorganic pyrophosphate from bovine and human teeth. PMID- 4299511 TI - [Cytomegalovirus hepatitis and pericarditis]. PMID- 4299512 TI - Hypothalamic-pituitary-adrenal function in the elderly. PMID- 4299513 TI - The determinants of left ventricular isovolumetric contraction time. PMID- 4299514 TI - Herpes simplex virus infection of the cornea. PMID- 4299515 TI - A case of foetal vaccinia. PMID- 4299516 TI - Breast cancer after exposure to the atomic bombings of Hiroshima and Nagasaki. PMID- 4299517 TI - Effects of vagal stimulation on S-A and A-V nodes. PMID- 4299518 TI - A renin-inactivating system in rat plasma. PMID- 4299519 TI - Effects of protein deficiency on certain adaptive responses to exercise. PMID- 4299520 TI - Effect of polynucleotides on aminoacyl transfer ribonucleic acid synthetases. 3. Inhibition of glutamyl transfer ribonucleic acid synthetase by natural polynucleotides. PMID- 4299521 TI - Fluorophenylalanine inhibition of tumors in mice on a phenylalanine-deficient diet. PMID- 4299522 TI - Some observations on the physicochemical properties of hemoglobin M-Hyde Park. PMID- 4299524 TI - Isolation and properties of mitochondrial RNA from yeast. PMID- 4299523 TI - Triphosphoinositide phosphomonoesterase in rat kidney cortex. II. Purification and characterization. PMID- 4299525 TI - Evidence for a substrate-mediated change in conformation of rabbit muscle aldolase. PMID- 4299526 TI - Reconstitution of the repeating unit of the mitochondrial inner membrane. PMID- 4299527 TI - Electron paramagnetic resonance spectroscy. Free radical signals associated with ozonization of linoleic acid. PMID- 4299528 TI - The survival of smallpox virus (variola minor) in natural circumstances. PMID- 4299530 TI - Corticotrophin preparations. PMID- 4299529 TI - [Therapeutic results in female genital tuberculosis]. PMID- 4299532 TI - Use of and limitations to the indirect hemagglutination test in the diagnosis of intestinal amebiasis. PMID- 4299531 TI - Use of newborn and infant animals in carcinogenicity testing. PMID- 4299533 TI - The quartz-iodine lamp for color and black-and-white photomicrography. PMID- 4299534 TI - Effect of magnesium deficiency on blood and liver transketolase activity and on the recovery of enzyme activity in thiamine-deficient rats receiving thiamine. PMID- 4299535 TI - Some compounds active as antirhinovirus in the plaque inhibition test. PMID- 4299536 TI - Gc group distributions in patients with cancer. PMID- 4299537 TI - Enchancement of the infectivity of simian virus 40 deoxyribonucleic acid with diethylaminoethyl-dextran. PMID- 4299538 TI - Induction of hepatomas by 4-aminobiphenyl and three of its hydroxylated derivatives administered to newborn mice. PMID- 4299539 TI - Multiplication of avian leukosis virus in the reproductive system of the rooster. PMID- 4299540 TI - Plasma cell leukemia in BALB-c mice inoculated with subcellular material. I. Incidence and morphology. PMID- 4299541 TI - Oncolytic potentials of nonhuman viruses for human cancer. II. Effects of five viruses on heterotransplantable human tumors. PMID- 4299542 TI - Dimethylnitrosamine-induced hepatic cell carcinoma in rainbow trout. PMID- 4299543 TI - Studies on L cells persistently infected with polyoma virus: relationship between D particle and other virus-like particles. PMID- 4299544 TI - The H-2 locus and viral leukemogenesis as studied in congenic strains of mice. PMID- 4299546 TI - Experimental improvements in the use of Silastic cuff for peripheral nerve repair. PMID- 4299545 TI - Cellular composition during tumor induction in rats by cycad husk. PMID- 4299547 TI - Nonaqueous titration of theophylline combinations with acetous perchloric acid. PMID- 4299548 TI - Effect of deuterium oxide on the culturing of Penicillium janczewskii. II. Isolation of fully deuterated griseofulvin. PMID- 4299549 TI - Epithelial cell malignancies of the parotid gland. PMID- 4299550 TI - Free radicals as possible contributors to tobacco-smoke carcinogenesis. PMID- 4299551 TI - Selective removal of components of tobacco smoke by filtration. PMID- 4299552 TI - Sequence analysis of specific areas of the 16S and 23S ribosomal RNAs. PMID- 4299553 TI - Regulation of citrate synthase and microbial taxonomy. PMID- 4299555 TI - [On emulsions in the subarachnoid space]. PMID- 4299554 TI - Enzymatic inactivation of streptomycin by R factor-resistant Escherichia coli. PMID- 4299556 TI - Dexamethasone-suppressible adrenocortical tumor. PMID- 4299558 TI - Bioelectronics. Intermolecular electron transfer may play a major role in biological regulation, defense, and cancer. PMID- 4299557 TI - [Level of serum gonadotropin in 50 cases of acromegaly]. PMID- 4299559 TI - Recovery of micro-quantities of steroids from silica gel following repeated thin layer chromatography. PMID- 4299560 TI - [Mice in cages. Some relations between behavior and adrenal cortex function]. PMID- 4299561 TI - [Determination of coagulase, phosphatase and DNase in staphylococcus]. PMID- 4299562 TI - [Pulmonary dusting and experimental infection. V. Effect of quartz dust on Calmette-Guerin bacillus infection in guinea pigs]. PMID- 4299564 TI - [Oxidation and splitting of aminophenol ethers. 4. On glycol splitting reagents]. PMID- 4299563 TI - [On the histology and histochemistry of xanthomatous histiocytoma]. PMID- 4299565 TI - [On the conversion of some enamines of beta-dicarbonyl-compounds with hypophosphorous acid]. PMID- 4299567 TI - [Problems of renovascular hypertension. Report on a international symposium on April 21-22, 1967 in Titisee-Schwarzwald]. PMID- 4299566 TI - [Toxicity of triphenylmethane dyes. Malachite green as an uncoupling agent of oxidative phosphorylation in vivo and in vitro]. PMID- 4299568 TI - [A new antibiotic with antineoplastic activity: rubidomycin (13.057 R.P.). II. Experimental antitumor activity]. PMID- 4299569 TI - [Blood pressure effect of adrenaline, noradrenaline, angiotensin and vasopressin on narcotized and despinalized golden hamsters]. PMID- 4299570 TI - [Puncture and contrast demonstration of the internal jugular vein. Application and diagnostic significance]. PMID- 4299571 TI - Action mechanism of glucose oxidase of Aspergillus niger. PMID- 4299572 TI - Comparison of Chlorobium thiosulphatophilum cytochrome c-555 with c-type cytochromes derived from algae and nonsulphur purple bacteria. PMID- 4299573 TI - Effect of phenobarbital on electron transport system, oxidation and reduction of drugs in liver microsomes of rats of different age. PMID- 4299575 TI - Characterization of the body weight-decreasing toxicities in mice by the lymphocytosis-promoting factor and the heat-labile toxin of B. pertussis and endotoxin. PMID- 4299574 TI - [Warning signs and early diagnosis of cancer of the breast]. PMID- 4299576 TI - Attempts at analysis of toxicity of pertussis vaccine. I. Body weight-decreasing toxicity in mice. PMID- 4299577 TI - An assay method for corticotropin-releasing activity by intrapituitary microinjection in the rat. PMID- 4299578 TI - [A contribution to the clinical diagnosis of the ectopic ACTH syndrome]. PMID- 4299579 TI - [Sacro-coccygeal tumors in children. Anatomical study of 15 cases]. PMID- 4299580 TI - [Drugs with an effect on the transmission of stimuli in the peripheral nervous system]. PMID- 4299581 TI - [Clinical contribution to glomus jugulare tumors]. PMID- 4299582 TI - Encephalitis in the newborn pup due to a canine herpesvirus. PMID- 4299583 TI - Spontaeous bluetongue in Texas white-tailed deer. PMID- 4299584 TI - [Horse sickness caused by type 9 virus in Central Africa: serological survey]. PMID- 4299585 TI - [Survey on the infection of cattle by parainfluenza 3 virus in Central Africa. Application to serological tests of pleuropneumonia]. PMID- 4299586 TI - [Occurrence of horse sickness virus type 9 in the Republic of Algeria: identification of virus strains isolated in 1965-1966]. PMID- 4299587 TI - Effect of hypophysectomy on the adrenal 17-hydroxycorticosteroid secretion in response to eserine in dogs. PMID- 4299588 TI - [A gigantic cylindroma of the paranasal sinuses]. PMID- 4299589 TI - [Intracellular distribution and some properties of soluble and lipid-bound catalase in normal liver and transplanted hepatoma]. PMID- 4299590 TI - [Effect of salin and sarcolysine on oxidative phosphorylation in mitochondria of tumor and normal cells]. PMID- 4299591 TI - [Effect of ACTH on glycogen levels in tissues of rats with acute hypoxyia]. PMID- 4299592 TI - [Age-related changed in the level of iron in tissues and DNA preparations from albino rats]. PMID- 4299593 TI - [The activity of glucose-6-phosphatase in the liver and kidney of hypophysectomized rats and induction of its synthesis after administration of ACTH and hydrocortisone]. PMID- 4299595 TI - [Glomus tumor of the mesentery of the large intestine (1 case)]. PMID- 4299594 TI - [Effect of nicotinamide on NAD levels and enzyme disintegration in the skeletal muscles of rabbits in normal conditions and after denervation]. PMID- 4299597 TI - [Study of autoimmunity in tumors induced by Rous virus in guinea pigs]. PMID- 4299596 TI - [On the histomorphology of lymph nodes after lymphography]. PMID- 4299598 TI - [Cellular ultrastructure of hepatomas induced in rats by 2-acetylaminofluorene]. PMID- 4299599 TI - [Determination of 4-methyluracil in the serum of normal and tumorous rats]. PMID- 4299600 TI - [Results of treatment of tumors of the testis]. PMID- 4299601 TI - [On the clinical picture and morphology of adenomatosis of the lungs in man]. PMID- 4299602 TI - [The effect of cancerogenous compounds on the free radical content in animal tissues]. PMID- 4299603 TI - [Free radicals and tumor growth]. PMID- 4299604 TI - [Light microscopic and radioautographic findings during cancerization of the rat liver with methyl-allyl-nitrosamine]. PMID- 4299606 TI - [The clinical picture of postural hypotension]. PMID- 4299605 TI - [Histochemical studies on the carcinoma of the corpus uteri. Enzyme distribution in the infiltrating parts of the tumor]. PMID- 4299607 TI - [Unusual tumors of the breast. Observation on the coincident appearance of a carcinoma and a sarcoma]. PMID- 4299608 TI - [Malignant hepatoma in a young female patient; survival after hepatic resection and removal of diaphragmatic and endothoracid metastasis]. PMID- 4299609 TI - Effect of epsilon amino caproic acid on adrenergic nerve function and tissue monoamine levels. PMID- 4299610 TI - [The cellular transplanted chloroleukemia. Electron microscopic results]. PMID- 4299611 TI - [ACTH in the treatment of multiple sclerosis]. PMID- 4299613 TI - [Introduction to neurohistochemistry]. PMID- 4299612 TI - [Oxidase, phosphatase]. PMID- 4299614 TI - Bovine herpes mammillitis virus. 3. Observations on experimental infection. PMID- 4299615 TI - [Clinical studies on urinary 17-ketogenic steroid fractions. 2. ACTH test in normal subjects and patients with various endocrine disorders]. PMID- 4299616 TI - [Our experiences with treatment of rheumatic fever with corticoids]. PMID- 4299617 TI - [Exceptional and very rapid improvement in a case of chronic pluricavitary tuberculosis treated with ethanbutel. (Clinical note)]. PMID- 4299618 TI - Peripheral nerve compression syndromes in the lower limb. PMID- 4299619 TI - Studies on the histochemistry of phosphatase enzymes in the juxtaglomerular complex. PMID- 4299620 TI - [Enzyme histochemical studies on cover slip tissue cultures in vivo]. PMID- 4299621 TI - Hydrolysis of riboflavin 5'-phosphate by phosphatases of rat kidney. PMID- 4299622 TI - [Morphological studies on the inguinal glands of rabbits. I. Histotopochemistry of various hydrolases]. PMID- 4299623 TI - Further study of the relationship between pre- and postsynaptic potentials in the squid giant synapse. AB - The minimal presynaptic depolarization (MPD) for producing a detectable postsynaptic potential (PSP) was lower than 25 mv in normal or tetrodotoxin (TTX) containing seawater. The MPD was about 10 mv when a small amount of tetraethylammonium ions (TEA) was injected into the presynaptic terminal. Application of linearly increasing depolarizing current to the normal presynaptic terminal at times produced a PSP before a presynaptic spike was evoked; the rate of rise of the resulting PSP was much slower than that of a PSP triggered by the normal presynaptic spike. A brief depolarizing pulse that preceded the presynaptic spike in normal seawater or the initial transient presynaptic depolarization in TTX decreased the PSP. It increased the PSP when it was applied during the spike or initial transient depolarization. Hyperpolarizing pulses had the reverse effect. The Off-PSP was also modified by inserting pulses at an initial part of the recovery phase of the strong presynaptic depolarization. These results indicate further that increases in Na(+) and K(+) conductance during presynaptic spike activity are not a requirement for transmitter release; the rate of release of transmitter can be controlled by electrical manipulation of the presynaptic terminal; there is a superficial correspondence between the time courses of presynaptic depolarization and the resulting PSP. Thus presynaptic depolarization appears to be only the first step in the series of events constituting excitation-transmitter release coupling. It may not be a necessary step for the release mechanism. PMID- 4299624 TI - [Experimental chemotherapy of Proteus vulgaris infection]. PMID- 4299626 TI - [Studies on steroid hormone stimulation therapy for chronic lung tuberculosis]. PMID- 4299625 TI - [Experimental chemotherapy of pseudomonas aeruginosa infections]. PMID- 4299627 TI - [Rhinovirus]. PMID- 4299628 TI - [Anatomic base of the clinical syndrome of median tarsal canal]. PMID- 4299629 TI - [Primary palatal tumors]. PMID- 4299630 TI - [Struma lingualis]. PMID- 4299631 TI - [Symposium on problems of essential arterial hypertension. Etiopathogenesis of essential hypertension]. PMID- 4299632 TI - [On the treatment of childhood enecephalopathies with spasm and hypsarrhythmia]. PMID- 4299633 TI - [On the finding of enteroviruses in the sewage at various stages of treatment in a sewage treatment plant with filtering beds]. PMID- 4299634 TI - [Experimental pathological studies on the metastasis of ascites tumors]. PMID- 4299635 TI - [Arachnoidal accumulations in the dura mater of the brain (experimental study)]. PMID- 4299636 TI - [Adaptation at the tissue level to different distributions of feeding in time]. PMID- 4299638 TI - [Estrogens in the menopause and senescence and their effect on the endometrium]. PMID- 4299637 TI - [Comparative studies on the metabolism of molds and dermatophytes. 2. Keratin degradation]. PMID- 4299640 TI - [Influence of experimental sodium chloride depletion on water-electrolyte metabolism, blood pressure and reaction ability of the vascula system in young hypertonics]. PMID- 4299641 TI - [Comparative studies on the behavior of equine rhinopneumonitis virus in different cell cultures]. PMID- 4299639 TI - [Model experiments in vitro for the proof of anaphylactoid effects]. PMID- 4299642 TI - Development of an attenuated live virus vaccine against sheep pox. PMID- 4299643 TI - [Studies on the localization of an ECBO virus in calf kidney cells with the help of a fluorescent antibodies]. PMID- 4299644 TI - [On the syndromology of lesions of Jacobson's nerve and Jacobson's anastomosis (recognition of disorders of the pre- and postsynaptic membrane of the cholinoreceptor)]. PMID- 4299645 TI - [Methods of determination of the sensitivity of cholera vibrios antibiotics]. PMID- 4299647 TI - [Effect of gramicidin C on the oxidative phosphorylation of Staphylococcus aureus]. PMID- 4299646 TI - [Effect of the combination of antibiotics on cholera vibrios]. PMID- 4299648 TI - The inhibition of glucose-6-phosphatase by phlorizin and structurally related compounds. PMID- 4299649 TI - Different oligomycin sensitivities of the Na++K+-activated adenosinetriphosphatase and its partial reactions. PMID- 4299650 TI - Specific anion binding effects on the reactive sites of hemerythrin. PMID- 4299651 TI - Antilipolytic acition of valinomycin and nonactin in isolated adipose cells through inhibition of adenyl cyclase. PMID- 4299652 TI - [On the modifications of orthodromic transmission of labyrinthic impulses through the vestibular neclei during sleep and wakefulness]. PMID- 4299654 TI - [Research on variations in the excitability of specific thalamic neurons during the sleep-wakefulness cycle]. PMID- 4299653 TI - [Tonic action exerted by the vestibular nuclei on postural tone in frogs]. PMID- 4299655 TI - [Power spectrum of the human electroencephalogram. 3. Modifications induced by intermittent sensory stimulations]. PMID- 4299656 TI - [Evidence for a natural inhibitor of renal origin of the renin-angiotensin system in man]. PMID- 4299657 TI - [Biochemical changes in the blood caused by the penetration of dichloroethan fumes through the skin]. PMID- 4299658 TI - The effect of heterologous antilymphocytic serum on the oncogenic activity of polyoma virus. PMID- 4299659 TI - [Glycogen metabolism in animal tissues--its regulation and disorders]. PMID- 4299660 TI - [Biosynthesis of collagen]. PMID- 4299662 TI - [Infectious enterotoxemia of camels caused by C1. perfringens, type C]. PMID- 4299663 TI - [Effects of aminazin on the blood coagulation system in some nervous system diseases]. PMID- 4299661 TI - [On the treatment of urogenital bilharziasis]. PMID- 4299664 TI - [State of the pituitary-adrenal system in patients with eosinophilic pituitary adenoma]. PMID- 4299665 TI - [Lipids and arteriosclerosis]. PMID- 4299666 TI - [Some criteria of the detection of interrelationships between bacteria and viruses. 3. Characteristics of respiration in intestinal bacterial in the adsorption of enteroviruses on them]. PMID- 4299667 TI - [Apropos of the pathogenesis of myasthenia gravis]. PMID- 4299668 TI - [Nervous system disorders in hyperinsulinism (syndrome of amyotrophic lateral sclerosis in adenoma of the pancreas)]. PMID- 4299669 TI - [Hypothalamic disorders in the initial period of bronchila asthma in children]. PMID- 4299670 TI - [The use of adrenal cortex hormones in rheumatic diseases of the nervous system and collagenoses in the neurological clinic (Review of the literature)]. PMID- 4299671 TI - [On the clinical aspects of lesions of the central nervous system in influenza and adenovirus infections in children]. PMID- 4299672 TI - [Psychopathologic and electroencephalographic characteristics of organic hyperinsulinism caused by insuloma]. PMID- 4299673 TI - [Clinical and experimental studies on iron metabolism in malignant neoplasms. 5. Isolation and purification of tumor ferritin and its intratumor cell distribution at the level of the electron microscope]. PMID- 4299674 TI - Effect of maternal and fetal hypophysectomy or adrenalectomy on the fetal extra adrenal chromaffin tissue of the rat. PMID- 4299675 TI - Secretory responses and respiratory enzymes of the rat's submaxillary gland after repeated teeth amputations. PMID- 4299677 TI - Serum placental lactogen levels in patients with molar pregnancy and trophoblastic tumors. PMID- 4299676 TI - Effect of directly and indirectly acting sympathomimetic amines on adrenergic transmitter granules. PMID- 4299679 TI - [Obliterating bronchiolitis. A propos of a case in a 10-month-old infant]. PMID- 4299678 TI - Thin-layer chromatography of keto acid dinitrophenylhydrazones of biological interest. PMID- 4299680 TI - A kinetic study of the production of light-induced ESR signals in Rhodospirillum rubrum chromatophores. PMID- 4299681 TI - The catalytic hydrolysis of phosphate ester bonds by thermal polymers of amino acids. PMID- 4299682 TI - Nucleotides associated with potato starch grains. PMID- 4299683 TI - Rate of ubiquinone oxidation in electron transport particles reduced by succinate. PMID- 4299684 TI - Purification and properties of rabbit muscle fructose 1,6-diphosphatase. PMID- 4299686 TI - Inhibition of viral hemagglutination by aggregated orosomucoid. PMID- 4299685 TI - The effect of carnitine, fatty acyl carnitine, and fatty acyl coenzyme A on mitochondrial contraction. PMID- 4299687 TI - A polarization of fluorescence study of alcohol dehydrogenase and its binary and ternary complexes. PMID- 4299688 TI - Stoichiometry of uncoupler to respiratory assembly in oxidative phosphorylation. PMID- 4299689 TI - Fourth national conference on Indian health. I. Respiratory infections. PMID- 4299690 TI - Occupational health in agriculture. Animal-borne diseases. PMID- 4299691 TI - Induction of deciduomata in normal and histamine-depleted rats. PMID- 4299692 TI - [Development-dependent mitochondrial enzyme activities in honey bee castes]. PMID- 4299693 TI - WHO collaborative studies on enterovirus reference antisera: second report. AB - This paper summarizes the results of the second part of co-operative studies undertaken by the WHO International Reference Centre for Enteroviruses and a number of WHO Regional Virus Reference Centres, WHO Virus Collaborating Laboratories and other laboratories in a comprehensive testing programme of enterovirus equine antisera. The studies were designed to appraise the specificity of immune serum prepared in horses against 16 representative prototype enteroviruses (polioviruses 2 and 3, coxsackieviruses A7, B1, B2, B4, B5 and B6 and echoviruses 1, 2, 3, 5, 7, 9, 12 and 17). Tests for neutralizing antibody were performed not only against the homologous viruses but also against the homotypic strains available in each laboratory. Tests for heterotypic antibody were made against the entire group of enteroviruses, reoviruses 1-3 and adenoviruses 1-11, 13 and 17. Each serum sample represented a pool of the individual bleedings taken from a group of horses before and after immunization with each virus antigen. The results showed that the homologous geometric mean titres of the immune sera ranged from 7000 to 36 000, whereas the preinoculation sera were negative. Results of the homotypic tests showed the usefulness of the sera. The specificity of the haemagglutination-inhibiting antibody of the sera against coxsackieviruses A7, B1, B5, B6 and echoviruses 3, 7, 12 was demonstrated. The results of the tests performed in tissue culture and mice are discussed. Co-operative testing of other enterovirus equine antisera is now in progress. PMID- 4299694 TI - [Study on the inactivation effect of beta-propiolactone on the Motol virus in animal experiment]. PMID- 4299695 TI - [Angiotensin II in the diagnosis of mineral-corticosteroid secretion disorders]. PMID- 4299696 TI - Morphological and histochemical studies on the autografts and homografts of the guinea-pig thyroid gland. (3.) Non-specific esterases, acid phosphatase, thiamine pyrophosphatase, and PAS-positive material. PMID- 4299697 TI - The activity of some hydrolytic enzymes in experimental hypoxia of the brain. PMID- 4299698 TI - [Antibiotic therapy of alveolar wounds]. PMID- 4299699 TI - Collagenase activity of gingival tissue affected with periodontal disease. PMID- 4299701 TI - [Virus demonstration in diseases of the cornea and conjunctiva]. PMID- 4299700 TI - Renin secretion in the perfused dog kidney. PMID- 4299702 TI - Activity of 3',5'-AMP phosphodiesterase in liver and adipose tissue of normal and diabetic rats. PMID- 4299703 TI - Maternal factor in the "hybrid effect" given by a spontaneous mammary carcinoma of C3H mice. PMID- 4299704 TI - A simple method for the determination of angiotensin I converting enzyme. PMID- 4299705 TI - The solid phase syntheses of 5-isoleucine-angiotensin I and 5-isoleucine (10 14C(U),-leucine)-angiotensin I. PMID- 4299707 TI - [On the diagnostic value of the angiotensin infusion test]. PMID- 4299706 TI - Levels of enzymes involved in glycolysis, gluconeogenesis, glycogenesis and hexosemonophosphate shunt in rat thyroid. PMID- 4299708 TI - What do we know about viruses? 4. Cytomegaloviruses. PMID- 4299709 TI - [The effect of specific polysaccharides of typhoid bacteria and proteus, with structure partially modified by acid hydrolysis, acetylation or oxidation, on the radiation resistence of mice]. PMID- 4299710 TI - Effectiveness of N1, N1-anhydrobis (beta-hydroxyethyl) biguanide hydrochloride (ABOB) in the treatment of pharyngoconjunctival fever. PMID- 4299711 TI - Physics of tissue damage. ORNL-4168. PMID- 4299712 TI - [Experience in the treatment of dyspepsia in calves]. PMID- 4299713 TI - [The morphology and functional pathology of tumors of the adenohypophysis in the dog]. PMID- 4299714 TI - Studies on cartilage formation. XI. Phosphoglucomutase and glucose-6-phosphatase activities of articular surface in various stages of regeneration. PMID- 4299715 TI - [Clinical virusology in acute respiratory infection in pediatrics]. PMID- 4299717 TI - Carcinoma of the esophagus involving the vagus nerves associated with gastric retention simulating pyloric obstruction. A case report. PMID- 4299716 TI - Amebic liver abscess. PMID- 4299718 TI - Azathioprine terapy of ulcerative colitis. PMID- 4299719 TI - Hydrogen cyanide and phenylthiocarbamide sensitivity, mid-phalangeal hair and color blindness in Yucatan, Mexico. PMID- 4299720 TI - A comparative study of the antigens of some of the 'histolytica-type" strains of Entamoeba. A qualitative and quantitative evaluation of antigens by indirect hemagglutination, gel-precipitation, and immunoelectrophoresis. PMID- 4299721 TI - Comparison of intradermal and serologic tests for the diagnosis of amebiasis. PMID- 4299722 TI - Studies to determine neutralizing antibody in sera from animals recovered from African swine fever and laboratory animals inoculated with African virus with adjuvants. PMID- 4299724 TI - Immune response of steers inoculated with chemically-treated foot-and-mouth disease virus preparations previously studied in swine. PMID- 4299723 TI - Enzyme studies in the embryonate egg and in tissue culture following inoculation with different viruses. PMID- 4299725 TI - Inhibition of antibody production in rats and mice by intravenous injection of interferon-inducing amounts of Sindbis virus or E. coli. PMID- 4299726 TI - A carrier cell line of measles virus in Lu 106 cells. PMID- 4299727 TI - Differences between the structures of poliovirus and Sindbis virus infectious ribonucleic acids. PMID- 4299729 TI - Characteristics of a C strain of foot-and-mouth disease virus propagated in BHK 21 cells. PMID- 4299728 TI - Influence and production of interferon in Rauscher virus infected mice. PMID- 4299730 TI - A clinical trial of Glenn type 3 attenuated poliovirus vacine. PMID- 4299731 TI - Interfering action of myxovirus on polyoma virus in primary mouse embryo cell cultures. PMID- 4299732 TI - [Characterization of various representatives of the Columbia-SK-virus group with fluorescent antibodies. I. The reproduction cycle of Mengo virus in L cells]. PMID- 4299733 TI - Recovery of cytomegalovirus from the submaxillary glands of ground squirrels. PMID- 4299734 TI - The development of antibodies against Sendai virus in childhood. PMID- 4299735 TI - Host-cell involvement in the expression of the guanidine-dependent phenotype of poliovirus. PMID- 4299736 TI - The influence of cations on the thermal inactivation of vesicular exanthema of swine virus. PMID- 4299737 TI - Biochemical studies on the teratogenic action of Bidrin and other neuroactive agents in developing hen eggs. PMID- 4299738 TI - Kinetic studies on the formation and destruction of the vasopressor polypeptide, substance A. PMID- 4299739 TI - ESR signal of mitochondria, microsome and hepatoma cell. PMID- 4299741 TI - Comparative studies on phospholipid metabolism in different tissues of guinea pig. II. With special reference to phosphoinositides. PMID- 4299740 TI - O-isopropylidene derivatives of D-allulose (D-psicose) and D-erythro-hexopyranos 2,3-diulose. PMID- 4299742 TI - Pathogenesis of sheep pox. PMID- 4299743 TI - [Lymphoadenography in the surgical therapy of neoplasms]. PMID- 4299744 TI - Tumors of the pancreas. PMID- 4299745 TI - Granulosa cell tumour and fibrosing thecoma (a report of two cases). PMID- 4299746 TI - Studies on the exophthalmos-producing substance in Bufo regularis. PMID- 4299747 TI - Histometric and histochemical studies of the hypothalamo-hypophyseal neurosecretory system of spontaneously hypertensive rats and rats with experimental hypertension. PMID- 4299748 TI - [Rheumatism and the endocrine system]. PMID- 4299749 TI - [Pituitary-adrenocortical function in corticoid management of skin diseases]. PMID- 4299750 TI - [Gas chromatographic estimation of urinary pregnanetriol, pregnanetriolone and pregnanetetrole before and during administration of ACTH, metopirone and corticosteroids in patients with congenital adrenal hyperplasia]. PMID- 4299751 TI - [Renal lesion and blood pressure change by injection of submicron crystalline silica suspension into renal artery]. PMID- 4299752 TI - [Weight loss and anorexia]. PMID- 4299754 TI - Oncogenesis and poliomyelitis vaccine. PMID- 4299753 TI - Parathyroid hormone-like action of N6-2'-O-dibutyryladenosine-3'5' (cyclic) monophosphate on bone explants in tissue culture. PMID- 4299755 TI - [On the formation of pigments and antibiotics in the species Streptomyces californicus (Waksman et Curtis 1916) Waksman et Henrici 1948]. PMID- 4299756 TI - The influence of the foetal adrenals on the development of the spleen of the rabbit foetus. PMID- 4299757 TI - Acute respiratory illnesses in university (1962-1966), military and industrial (1962-1963) populations. PMID- 4299758 TI - Biochemical study on the host response to tuberculous infection. IV. Influences of isoniazid, streptomycin, nicotinamide, and cortisone. PMID- 4299759 TI - Aortopulmonary collateral flow in patients with pulmonary disease. PMID- 4299760 TI - The nature of "depolarization block". PMID- 4299761 TI - Potentiation of muscle relaxants by quinidine. PMID- 4299762 TI - Potentiation of muscle relaxants by quinidine. PMID- 4299763 TI - Monosynaptic transmission in the cat's spinal cord. A quantitative measure of anesthetic dose. PMID- 4299764 TI - Hyperprolinaemia in two successive generations of a North American Indian family. PMID- 4299765 TI - The prognosis of lupus nephritis. Role of clinical-pathologic correlations. PMID- 4299766 TI - [On a rare case of glomic tumor located in the inferior vestibular fornix]. PMID- 4299768 TI - [Use of tumor cells of different animal ascitic strains for primary selection of antitumor antibiotics]. PMID- 4299767 TI - The problem of local recurrence after treatment of soft tissue sarcoma. PMID- 4299769 TI - [Studies for the production of genetically pure avirulent lines of hoof-and-mouth disease virus by means of the plaque method and of "limiting infective dilutions"]. PMID- 4299770 TI - Comparative studies with the Zilber (Carr) strain of Rous sarcoma virus (Z-RSV). 3. Suppression of viral replication and focus formation by interferon in vitro. PMID- 4299771 TI - Differentiation of reoviruses and picornaviruses by density gradient centrifugation. PMID- 4299772 TI - Foot-and-mouth disease in swine. I. The immune response of swine of chemically treated and non-treated foot-and-mouth disease virus. PMID- 4299774 TI - Properties of a new type 3 attenuated poliovirus. VI. Alimentary tract resistance in children fed previously with type 3 Sabin vaccine to reinfection with homologous and heterologous type 3 attenuated poliovirus. PMID- 4299773 TI - The influence of the host cell, ionic strength and chymotrypsin on foot-and-mouth disease virus electrophoretic mobility. PMID- 4299776 TI - The role of game animals in the epizootiology of rinderpest and malignant catarrhal fever in East Africa. PMID- 4299775 TI - Assessment of long-acting synthetic corticotrophin in hypersensitive asthmatics and normal subjects. AB - The synthetic polypeptide depot-tetracosactrin (Synacthen-Depot) was given to nine steroid-treated asthmatic patients hypersensitive to animal corticotrophin. Eight had a satisfactory increase in plasma and urinary 17-hydroxycorticosteroids (17-OHCS). The remaining patient had been shown previously to have adrenal suppression. None of the patients developed allergic reactions to depot tetracosactrin, and seven have been receiving regular injections of the polypeptide twice weekly for the past eight months.In 13 normal subjects intramuscular injections of 1 mg. and 0.5 mg. of depot-tetracosactrin and 40 units of corticotrophin-gel were equally potent in raising the plasma 17-OHCS, but depot-tetracosactrin had a significantly longer action than corticotrophin gel. PMID- 4299777 TI - Glomus tumours of the temporal bone. PMID- 4299778 TI - Sarcomas and sarcomatoid and mixed malignant tumors of the kidney in adults. 3. PMID- 4299779 TI - Carcinoma of the male breast following radiation. Report of a case occurring 35 years after radiation therapy of unilateral prepubertal gynecomastia. PMID- 4299780 TI - Conceptual unity of the Mullerian tumor group. A histologic study. PMID- 4299781 TI - Central mucoepidermoid tumors of the jaws. Review of the literature and case report. PMID- 4299782 TI - Testicular neoplasms in an infant. PMID- 4299783 TI - Primary carcinoma of the liver in Mexican adults. PMID- 4299784 TI - [Diagnostic procedures in cytomegalic inclusion disease]. PMID- 4299785 TI - [Methods and results of clinical neuropharmacology]. PMID- 4299787 TI - The pathology of murine runting and its modification by neomycin sulphate gavages. PMID- 4299786 TI - A simple index for the measurement of the runting syndrome and its use in the study of the influence of the gut flora in its production. PMID- 4299788 TI - Estimation of liver and intestine lipids of rat by silicic acid column chromatography. PMID- 4299789 TI - Separation of retinol from neutral lipids and phospholipids by silicic acid. PMID- 4299790 TI - Phytase from Bacillus subtilis. PMID- 4299791 TI - Adenovirus infections in Kottayam (Kerala): a preliminary report. PMID- 4299792 TI - Isolation of kanamycin and paromamine inactivated by E. coli carrying R factor. PMID- 4299793 TI - Biological timing and the dento-facial complex. 3. PMID- 4299795 TI - Pulsatile blood flow of gliomas studies with implanted impedance electrodes. PMID- 4299796 TI - Dangers of oxidized cellulose in chiasmal surgery. Report of two cases. PMID- 4299794 TI - Taste changes in vitamin A deficiency. AB - Taste preferences were studied in two groups of rats depleted of vitamin A by dietary restriction. One group received sufficient vitamin A acid supplement to maintain normal growth. The other group was repleted with vitamin A alcohol after the classical deficiency symptoms had appeared; this group gradually lost normal preferences for NaCl and aversion to quinine solutions during depletion. Vitamin A alcohol repletion tended to restore taste preferences to normal. In contrast, the group receiving vitamin A acid showed normal taste preferences throughout the depletion period. When the vitamin A acid supplement was removed taste preferences became abnormal and returned to normal when vitamin A acid was restored. Peripheral gustatory neural activity of depleted rats without any form of vitamin A was less than normal both at rest and when the tongue was stimulated with NaCl solutions. Histological examination showed keratin infiltrating the pores of the taste buds. Accessory glandular tissues were atrophied and debris filled the trenches of the papillae. It is concluded that vitamin A acid can provide the vitamin A required for normal taste, as contrasted with its inability to maintain visual function. It is suggested that the effect of vitamin A is exerted at the receptor level, as a result of its role in the biosynthesis of mucopolysaccharides, which have been recently identified in the pore area of taste buds, as well as being present in the various secretions of the oral cavity. PMID- 4299797 TI - [Cytomegalic inclusion disease]. PMID- 4299798 TI - [Medullary scintigraphy. Technic with intravenous injection of Tc99m]. PMID- 4299799 TI - Glucose-6-phosphatase activity of mouse pancreatic islets. PMID- 4299800 TI - Glyceraldehyde 3-phosphate dehydrogenase from pig muscle. PMID- 4299801 TI - Proposed mode of action of histamine. PMID- 4299802 TI - [The importance of the renin-angiotensin system during pregnancy. A current problem]. PMID- 4299803 TI - [A little known polydysplasia with patchy dermal hypoplasia]. PMID- 4299805 TI - Nucleic acid molecules: new microdiffusion technique for visualization. AB - A microdiffusion technique, developed for visualization of nucleic acid molecules in the electron microscope, requires less than 0.01 microgram of nucleic acid. Although originally developed for free nucleic acids, the method can be applied to virion suspensions for direct visualization of their genomes; less than 10(10) virions per milliliter are required. Results agree well with those yielded by the diffusion technique of Lang, Kleinschmidt, and Zahn. PMID- 4299806 TI - Herpesvirus type 2: association with carcinoma of the cervix. AB - By utilizing the kinetics of neutralization, it was found that an antibody response to type 1 (oral) and type 2 (genital) herpesvirus infection could be independently measured and correlated with type of virus isolated from the patient. The presence of antibodies to type 1 and type 2 herpesvirus was examined in patients with carcinoma of the cervix, in matched controls, random controls, and patients with other types of malignancy. Antibodies to type 2 were found with greater frequency in patients with carcinoma of the cervix (83 percent) than in the other groups tested (0 to 20 percent). The data suggest an association of genital herpesvirus and carcinoma of the cervix. PMID- 4299804 TI - Engrams in the human brain. Mechanisms of memory. PMID- 4299807 TI - Excited electronic states of DNA. PMID- 4299808 TI - Induction of collagenolytic and proteolytic activities in rat and human fibroblasts by anti-inflammatory drugs. AB - Confluent monolayers of either mouse or diploid human fibroblasts contained no measurable amounts of either collagenolytic (pH 5.5) or proteolytic (pH 7.5) activities. Within a few hours after exposure of these cells to antiinflammatory drugs, significant amounts of these enzymatic activities were demonstrable extracellularly. These activities were profoundly decreased in cultures simultaneously treated with the anti-inflammatory drugs and cycloheximide or actinomycin D. PMID- 4299809 TI - [A case of restoration of the thumb in congenital defective development of the hand]. PMID- 4299810 TI - [On free transplantation to the wound surface following resection of the maxilla]. PMID- 4299811 TI - [On the symptomatology of intrathoracic tumors]. PMID- 4299812 TI - [The secondary sensitivity of mycobacteria]. PMID- 4299813 TI - Studies on the histochemical distribution of oxidative enzymes in olfactory bulb of rat. PMID- 4299814 TI - A comparative study on the localization of certain enzyme activities in the testes of the Indian desert gerbil and the house shrew. PMID- 4299815 TI - Clinical virology and viral surveillance in a pediatric group practice: the use of double-seeded tissue culture tubes for primary virus isolation. PMID- 4299817 TI - A subclinical outbreak of human rhinovirus 31 infection in chimpanzees. PMID- 4299816 TI - Respiratory syncytial virus associated with acute respiratory infections in Trinidadian patients. PMID- 4299818 TI - Bovine papular stomatitis: experimental transmission from man. PMID- 4299819 TI - Studies on the biosynthesis of nicotinamide adenine dinucleotide (NAD) in mammals and its regulatory mechanism. I. PMID- 4299820 TI - The resolution of some steps of the reactions of lactate dehydrogenase with its substrates. AB - 1. The reaction of pig heart lactate dehydrogenase (EC 1.1.1.27) with NAD(+) and lactate to form pyruvate and NADH was followed by rapid spectrophotometric methods. The distinct spectrum of enzyme-bound NADH permits the measurement of the rate of dissociation of this compound. 2. The reduction of the first mole equivalent of NAD(+) per mole of enzyme sites can also be observed, and is much more rapid than the steady-state rate of NADH production. 3. At pH8 the dissociation of the enzyme-NADH complex is rate-determining for the steady-state oxidation of lactate. At lower pH some other step after the interconversion of the ternary complex and before the dissociation of NADH is rate-determining. Other evidence for a compulsory-order mechanism is provided. PMID- 4299821 TI - A spectrophotometric method for the microdetermination of periodate. AB - 1. A method is described for measuring the concentration of periodate over the range 0.2-20mum by adding 1,2-di-(p-dimethylaminophenyl)ethane-1,2-diol to a sample solution. Periodate cleaves this compound to from two molecules of p dimethylaminobenzaldehyde, the extinction of which is then read at 352mmu. 2. The method has been used to follow the course of periodate oxidations of serine methyl ester, ribonuclease A and ribonuclease S-protein. Addition of the reagent stops further periodate reaction by reducing the remaining periodate to iodate. 3. The presence of protein does not interfere with the assay. PMID- 4299822 TI - Detection of infectious bovine rhinotracheitis (IBR) by immunofluorescence. AB - Infectious bovine rhinotracheitis can be readily and accurately diagnosed by direct fluorescent antibody techniques on infected bovine embryo kidney monolayers. Non-specific fluorescence was encountered in direct observation of bovine nasal secretions and cotyledon impressions. PMID- 4299823 TI - Plaque morphology of Teschen disease viruses and certain pig enteroviruses in primary pig kidney monolayer cultures. AB - Plaque patterns and diameters of four virulent strains and one tissue culture mutant of Teschen disease virus were compared with six pig enteroviruses isolated in the United States. They are described as they were produced in primary pig kidney monolayer cultures. Reproducible plaques, with similar characteristics and class-types of each of the viruses tested were obtained with the application of a 45-minute virus adsorption time. Their morphologic characteristics and the proportion in which the plaque types appeared may assist in the differentiation of these virus strains. PMID- 4299824 TI - Streptozotocin: depression of mouse liver pyridine nucleotides. PMID- 4299825 TI - The investigation of some antigens of Zajdela ascitic rat hepatoma cells. PMID- 4299827 TI - Chronotropic and pressor responses to angiotensin in rats anaesthetised with urethane. PMID- 4299826 TI - Glycolysis in chick embryo cell cultures transformed by Rous sarcoma virus. PMID- 4299828 TI - Effects of curare-like agents on the block of tetanic contractions produced by neostigmine in the rat. PMID- 4299829 TI - An action of 5-hydroxytryptamine on the frog motor end-plate. PMID- 4299830 TI - [Results of radiotherapy in glomus tumors]. PMID- 4299831 TI - Evaluation of a family care program for released mental patients. PMID- 4299832 TI - Effects of viomycin and polymyxin B on protein synthesis in vitro. PMID- 4299834 TI - Effect of the chelating agents, EDTA, 2,2'-bipyridine, 8-hydroxyquinoline and pyrophosphoric acid, on norepinephrine uptake by rabbit aorta. PMID- 4299833 TI - Structure and base sequence in the cohesive ends of bacteriophage lambda DNA. PMID- 4299835 TI - Relaxant effect of cyclic adenosine 3',5'-monophosphate on the isolated rabbit ileum. PMID- 4299836 TI - Herpesvirus hominis infection at a smallpox vaccination site. PMID- 4299837 TI - [Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders]. PMID- 4299838 TI - [Excision of hepatic lobe for primary cancer of the liver]. PMID- 4299839 TI - Experimental herpes virus infection in young puppies. PMID- 4299840 TI - [Evaluation of peripheral nerve palsy in newborn babies]. PMID- 4299841 TI - [Function of the adrenal cortex in patients with lung cancer]. PMID- 4299842 TI - [Classification and identification of slowly growing atypical mycobacteria]. PMID- 4299843 TI - A morphological and histochemical study of the subcommissural organ of young and old sheep. PMID- 4299844 TI - Cyclic AMP. PMID- 4299846 TI - Histidinemia and atopic dermatitis. PMID- 4299845 TI - Pemphigus foliaceus or erythema multiforme. PMID- 4299847 TI - Tinea rubrum. 1. Tinea pedis and cruris. 2. Verrucous dermatitis perianal. Extramammary Paget's disease. PMID- 4299848 TI - Biochemical and clinical studies in familial goitre caused by an iodotyrosine deiodinase defect. PMID- 4299849 TI - [Interaction of phosphates with electron acceptors]. PMID- 4299850 TI - [Determination of the parameters of ESR spectra of free radicals by internal standards]. PMID- 4299851 TI - [Comparative characterization of radical states, originating in crystalline trypsin under irradiation by protons with the energy of 660 mv and gamma quantums]. PMID- 4299852 TI - [Study of ubiquinones in mitochondria and tissues of animals and plants of vitamin K in E. coli B bacteria using the ESR method]. PMID- 4299854 TI - Leprosy. PMID- 4299853 TI - A planned approach to the surgical patient with iatrogenic adenocortical insufficiency. PMID- 4299855 TI - [Study of the karyotypic sex of a transplantable neoplasm in the polyoma-hamster system]. PMID- 4299856 TI - Tumors of the scapula. A review of the literature and an analysis of 31 cases. PMID- 4299857 TI - Changes in thyroid secretion produced by inhibition of iodotyrosine deiodinase. PMID- 4299858 TI - Relation of the mass of heterotopic pituitary tissue to its ability to secrete ACTH and TSH in response to amino-glutethimide. PMID- 4299859 TI - Hypocalcemic effect of imidazole in rats. PMID- 4299860 TI - Alteration of adrenocortical steroidogenesis in the rat by inhibition of cholesterol biosynthesis. PMID- 4299861 TI - Enzymes of glucose formation and turnover in x-irradiated rats. PMID- 4299862 TI - A comparison of the effects of x-radiation on the relative rates of incorporation of labelled thymidine and cytidine into mitochondrial and nuclear DNA of Morris hepatomas. PMID- 4299863 TI - Pathway for oxidative dissimilation of glycerol in Bacillur subtilis. PMID- 4299865 TI - The effect of fasting on glucose utilization in the isolated perfused rat liver. PMID- 4299864 TI - Hemorrhagic cystitis: adenovirus type 11. PMID- 4299866 TI - [Histologic and histochemical aspects of familial gingival fibromatosis]. PMID- 4299867 TI - [Clinical considerations on mixed salivary tumors in a central mandibular position]. PMID- 4299868 TI - [Histoenzymologic study of 3 cases of intestinal atrophy]. PMID- 4299869 TI - [Importance of erythrocyte magnesium in the diagnosis and treatment of certain tetanies]. PMID- 4299870 TI - [Nobel prize for Henry Hallet Dale and Otto Loevi in 1936 for discovery and explanation of chemical transmission of nervous impulses]. PMID- 4299872 TI - [The mesenchymomas. Attempted anatomo-clinical restatement]. PMID- 4299871 TI - [Study of the synchronization of motor neuron discharges in persons with poliomyelitis]. PMID- 4299873 TI - [A case of Schilder's diffuse encephalitis periaxialis. I. Anatomo-clinical study]. PMID- 4299874 TI - [The embryoid morphogenesis of germinal tumors]. PMID- 4299875 TI - [Demonstration of the virus of hemocytoblastic reticular mice leukemia (Mazurenko) from leukemia ascites]. PMID- 4299876 TI - Functional morphology of the pars intermedia of the rat hypophysis as revealed with the electron microscope. 3. Effects of dexamethasone on the pars intermedia of rats under various experimental conditions. PMID- 4299877 TI - [On the mechanism of reaction of quinones with hydroxyl-ions]. PMID- 4299878 TI - [Free radical states of cell and subcellular structures]. PMID- 4299879 TI - [I. On the nature of free radical states of plant tissues]. PMID- 4299880 TI - [Electron spin resonance in animal tissues in some kinds of tissue hypoxia]. PMID- 4299881 TI - [Cylindroma in disseminated elements and cranial bone lesions]. PMID- 4299882 TI - [Can adenomatoid malfrmation of the lung be observed in an older child? (Apropos of a case)]. PMID- 4299883 TI - [Discrimination of the nerve information routes by treatment of the group of impulses set apart on the nerve]. PMID- 4299884 TI - [Extraction of stimulon from cells transformed by adenovirus 12 or by simian virus 40 (SV 40)]. PMID- 4299885 TI - [On the interrelationship of antibiotics with heparin]. PMID- 4299886 TI - [Effect of strophantin on some indices of energy metabolism in the kidneys]. PMID- 4299887 TI - In vitro and in vivo evaluation of enduracidin, a new peptide antibiotic substance. PMID- 4299888 TI - Antiviral activity of trichothecin. PMID- 4299889 TI - Antiviral activity of brefeldin A and verrucarin A. PMID- 4299890 TI - Serum turbidity responses of anti-inflammatory drugs in endocrine-deficient rats. PMID- 4299891 TI - Regulation of pyridine nucleotide coenzymes. PMID- 4299892 TI - The biosynthesis of NAD in the liver of irradiated mice. PMID- 4299893 TI - Polymerization of ADPR moiety of NAD by nuclear enzyme preparation. PMID- 4299894 TI - Poly adenosine diphosphate ribose synthesis and nicotinamide adenine dinucleotide transglycosidases. PMID- 4299895 TI - Suppression of growth of herpes simplex virus in chick embryo fibroblasts at 40 degrees C. PMID- 4299896 TI - [The surgical treatment of a patient with renovascular hypertension and the significance of the renin-angiotensin system in its development]. PMID- 4299897 TI - [The practitioner and psychiatric after care]. PMID- 4299898 TI - Site of the inhibiting action of diphenylhydantoin on the release of corticotrophin in epileptic patients. PMID- 4299899 TI - [New studies on cancerostasis]. PMID- 4299900 TI - Treatment of concer in childhood. PMID- 4299901 TI - Diencephalic syndrome of emaciation: a case report with special reference to the mechanism of hypothalamic dysfunction. PMID- 4299902 TI - [Inactivation of alkaline phosphatase solutions with gamma-radiation Co60 and the study of various properties of irradiated phosphatases]. PMID- 4299903 TI - [Structures of pathways and centers of pain sensitivity. Morphological and functional bases of analgesic surgery]. PMID- 4299904 TI - [Causalgia and other sympathetic reflex dystrophies]. PMID- 4299905 TI - [Therapy of neoplastic pain with neurolytic agents]. PMID- 4299906 TI - [Classification and pathogenesis of Felty's syndrome. (2 cases studying hematologic anomalies by isotope technic)]. PMID- 4299907 TI - [Serologic tests of German measles by hemagglutination inhibition in hospital patients. Study of 800 serums]. PMID- 4299908 TI - [A Vibrio foetus infection in a man having myeloid splenomegaly and an acute polyvisceral tuberculosis]. PMID- 4299909 TI - [Clinical classification of asthma]. PMID- 4299910 TI - [Intra-arterial infusions in the treatment of cancer]. PMID- 4299911 TI - [Treatment of meningeal hemorrhage by intraspinal injection of betamethasone phosphate]. PMID- 4299912 TI - Studies on phenolic steroids in human subjects. XI. The biosynthesis and proof of structure of estriol-3,16-diglucosiduronate. PMID- 4299913 TI - [Isolation of viral RNA from infected cells by thermal fractionation]. PMID- 4299914 TI - [Clinical picture and surgical treatment of vasucular tumors of the spinal cord]. PMID- 4299915 TI - [Cholinesterase activity in the tissues of glial tumors of the brain]. PMID- 4299916 TI - [Efficacy of active immunization in the prevention of intrauterine Clostridium perifringens infection in pregnant mice]. PMID- 4299917 TI - [Preliminary electron microscopic study of Myxovirus parainfluenzae II]. PMID- 4299918 TI - [Study of plasma growth hormone and ACTH levels in various states of pituitary adrenal dysfunction]. PMID- 4299919 TI - [Experimental contributions to the recognition of dermatitis pustulosa in sheep. 3. The resistance of infectious and complement binding antigen against increased temperatures]. PMID- 4299920 TI - [Experimental contributions to the recognition of dermatitis pustulosa in sheep. V. Investigations into the development of immunity against the dermatitis pustulosa virus at various places of the body surface]. PMID- 4299921 TI - [Experimental contributions to the recognition of dermatitis pustulosa in sheep. VI. The specificity of the complement binding reaction with dermatitis pustulosa antigen]. PMID- 4299922 TI - [Experimental contributions on the recognition of dermatitis pustulosa in sheep. VII. Studies of the processes in the cold complement binding reaction with dermatitis pustulosa antigen]. PMID- 4299923 TI - [The fractionation of foot-and-mouth disease hyperimmune serum from cattle by combination of gel filtration and column electrophoresis]. PMID- 4299924 TI - [The action of the detergent RBS-25 on various animal viruses]. PMID- 4299925 TI - [On the etiology of milker's nodes]. PMID- 4299926 TI - [Experimental studies on the influence of dust on the formation of the roentgen picture in pneumoconioses]. PMID- 4299927 TI - [Development of occupational risk and working conditions in the asbestos industry during the last 20 years]. PMID- 4299928 TI - [On a rare case of angioma of the masseter muscle]. PMID- 4299929 TI - [Spectrophotometric determination of alpha and beta isomers of NAD]. PMID- 4299931 TI - [Effect of dithiophos and malathion on the effect of some narcotic compounds]. PMID- 4299932 TI - [E.S.R. signals observed on the retina and optic nerve]. PMID- 4299930 TI - [Age related aspects of the reaction of the organism to catecholamines]. PMID- 4299933 TI - [Disturbances of pulmonary function after lymphography]. PMID- 4299934 TI - [Action of serotonin and crustacean diabetogenic hormone on muscle phosphorylase]. PMID- 4299935 TI - Effects of some vertebrate hormones on lipid mobilization in the insect fat body. PMID- 4299936 TI - Response of the interrenal gland of rainbow trout (Salmo gairdneri) to stress. PMID- 4299937 TI - Histochemical and biochemical studies of the corpuscles of Stannius of the teleost fish Colisa ialia. PMID- 4299939 TI - Representation of information in neurons and sites for molecular participation. PMID- 4299938 TI - [Clinical aspects of 3rd ventricle tumors]. PMID- 4299940 TI - The neuronal membrane. PMID- 4299941 TI - Osteosarcomas appearing in Syrian hamsters after treatment with extracts of human osteosarcomas. PMID- 4299942 TI - Demonstration of cell-bound and humoral immunity against neuroblastoma cells. PMID- 4299943 TI - The integrated state of viral DNA in SV40-transformed cells. PMID- 4299944 TI - Generation of slow postsynaptic potentials without increases in ionic conductance. PMID- 4299945 TI - Mechanism of DNA chain growth, II. Accumulation of newly synthesized short chains in E. coli infected with ligase-defective T4 phages. PMID- 4299946 TI - An early alteration in the phospholipid metabolism of lymphocytes by phytohemagglutinin. PMID- 4299947 TI - Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors. PMID- 4299949 TI - [Biosynthesis of ADP ribose polymer from NAD with nuclear enzymes]. PMID- 4299948 TI - Physical properties of Rous Sarcoma Virus RNA. PMID- 4299950 TI - Experimental investigation of shake emulsions of radiopaque oils in the cranial subarachnoid space. PMID- 4299951 TI - [The angiographic diagnosis of unusual renal cortex tumors]. PMID- 4299952 TI - [Current knowledge of histoenzymology at the level of the normal and pathologic human kidney]. PMID- 4299953 TI - [Compression of the esophagus by an inferior lobar cancer of the left lung]. PMID- 4299954 TI - [Peptic ulcer after gastroenterostomy and mucous diverticula of the orifice of the anastomosis]. PMID- 4299955 TI - [Syndrome of the afferent loop after gastrectomy]. PMID- 4299956 TI - [4 cases of muco-erosive gastric cancer]. PMID- 4299957 TI - [Hypertrophic gastritis and prepyloric epithelioma]. PMID- 4299958 TI - [Hypertrophic gastritis and cardic-curvature epithelioma]. PMID- 4299959 TI - [Radiologic image of tumoral infiltration of the posterior surface of the greater curvature of the stomach centered by an immense ulceration: reticulosarcoma]. PMID- 4299961 TI - [Gastric localization of Hodgkin's disease]. PMID- 4299960 TI - [2 duodenal diverticula and gastric cancer]. PMID- 4299962 TI - [Leiomyoma of the second duodenum]. PMID- 4299963 TI - [Hernia of the small intestine in a retroduodenal fossette. Importance of selective arteriography of the superior mesenteric artery]. PMID- 4299964 TI - [Post-traumatic stenosis of the small intestine]. PMID- 4299965 TI - [Selective arteriography of the superior mesenteric artery in the Peutz-Jeghers syndrome]. PMID- 4299966 TI - [Stenotic form of Crohn's terminal ileitis]. PMID- 4299967 TI - [Carcinoid tumor of the terminal ileum]. PMID- 4299968 TI - [Lymphosarcoma of the terminal ileum]. PMID- 4299969 TI - [Invagination of the appendix on cancer of the cecum]. PMID- 4299970 TI - [Double cancer of the colon]. PMID- 4299972 TI - [Sigmoid cyst]. PMID- 4299971 TI - [Invaginated rectosigmoid villose tumor]. PMID- 4299973 TI - [Apropos of inflammatory tumors of the cecum]. PMID- 4299974 TI - [Torsion of the great epiploon]. PMID- 4299975 TI - [Segmental benign stenosis of the common bile duct]. PMID- 4299976 TI - [Pseudotumoral sclerous odditis]. PMID- 4299977 TI - [A case of duodeno-cholecysto-colic fistula of lithiasic origin]. PMID- 4299978 TI - [Recurrent lithiasis of the common bile duct]. PMID- 4299979 TI - [Hydatid cyst of the convexity of the liver]. PMID- 4299980 TI - [Primary cancer of the liver in a child detected by angiography and treated by exeresis and antimitotics]. PMID- 4299981 TI - [Right diaphragmatic eventration simulating a hydati cyst of the liver in a 5 year-old child]. PMID- 4299982 TI - [Apropos of a hepatoma: role of regional chemotherapy]. PMID- 4299983 TI - [Cancer of the body of the pancreas with hepatic metastases]. PMID- 4299984 TI - [Calcification of the splenic artery]. PMID- 4299985 TI - [Test of an antiviral treatment in some cutaneo-mucosal diseases]. PMID- 4299986 TI - [The virology of acute respiratory tract infections. 1. A survey on the etiology in children]. PMID- 4299987 TI - [The virology of acute respiratory tract infections. 2. Isolation of viruses in hospitalized children]. PMID- 4299988 TI - [On the clinical manifestations of tumors of the frontal lobe of the brain]. PMID- 4299989 TI - [Electron microscopic study of glioblastoma multiforme]. PMID- 4299990 TI - [On extrapyramidal pathology in tumors of the optic thalamus]. PMID- 4299991 TI - [Specific functions of the female organism in tumors of the 3rd ventricle (clinical, functional and morphologic studies)]. PMID- 4299992 TI - [Electrophoretic study of cerebrospinal fluid proteins in gliomas of the cerebral hemispheres]. PMID- 4299993 TI - [On the clinical characteristics of epileptic seizures in cerebral convexital arachnoiditis]. PMID- 4299994 TI - Vascular response to vasopressin as reflected in angiography. An experimental study in the dog. PMID- 4299995 TI - [On the problem of infiltrations of the central nervous system in virus-induced murine leukemias]. PMID- 4299996 TI - [Experiments for the demonstration of the Graffi leukemia virus in tissues of infected animals of various species]. PMID- 4299997 TI - [Karyometric observations on the periodic acid-Schiff positive cells of the hypophysis of rats with Walker or Jensen tumors]. PMID- 4299998 TI - [On clinical aspects of the primary liver carcinoma. Catamnetic studies of 124 patients]. PMID- 4299999 TI - Community and hospital outbreak of epidemic keratoconjunctivitis. PMID- 4300000 TI - Wilms' tumor metastatic to the orbit. PMID- 4300001 TI - Collagenolytic activity in bovine corneal epithelium. PMID- 4300002 TI - Genetic transmission of mammary tumor inciting viruses in mice; possible implications for murine leukemia. PMID- 4300003 TI - The influence of antibodies in vivo and in vitro on cellular and cell-free preparations of atype 3 avian leukosis virus. PMID- 4300005 TI - Interactions of RNA oncogenic viruses and cells. PMID- 4300004 TI - Avian leukemia and sarcoma studies. PMID- 4300006 TI - Leukosis viruses of chicken structure, antigenic behaviour and cell interactions. PMID- 4300007 TI - Recent studies on leukemia and solid tumors in mice and man. PMID- 4300008 TI - Correlative biological and ultrastructural studies on Rous sarcoma virus in various hosts. PMID- 4300009 TI - Antibodies in primates to human and simian viruses: a comparative study. PMID- 4300010 TI - Biochemical studies on cells infectd with RNA-containing tumor viruses. PMID- 4300011 TI - Role of immunological tolerance in viral leukemogenesis of the mouse. PMID- 4300012 TI - Recent studies on the etiology of mouse leukemia and lymphomas. PMID- 4300013 TI - Electron microscopic studies on the organ distribution of GRAFFI leukemia virus in leukemic and preleukemic mice. PMID- 4300014 TI - Ability of an erythropoietic virus to initiate erythropoiesis in hypertransfused polycythemic mice. PMID- 4300015 TI - Multiplicity of cell response to a murine erythroblastosis virus. PMID- 4300016 TI - Pathology of virus leukemia in the mouse. PMID- 4300017 TI - Studies on virus attenuation in mouse leukemia. PMID- 4300018 TI - Biological and physical properties of a leukemogenic agent of a new type of viral murine leukemia. PMID- 4300019 TI - [Homeostasis of the cerebral, retinal and cochlear circulation]. PMID- 4300020 TI - [Horton's syndrome and its ocular manifestations]. PMID- 4300021 TI - [The absence of interaction between nervous and chemical stimulation on respiration inmedium intensity muscular activity]. PMID- 4300022 TI - [State of oxido-reduction of the NAD-NADH system of the tissues in dogs treated with thyroxine]. PMID- 4300023 TI - [State of oxido-reduction of blood NAD-NADH in dogs treated with small doses of triiodothyronine]. PMID- 4300024 TI - [Research on experimental electrocardiography. I. Effect of Myxovirus para influenzae type 1 on the ECG of newborn rats]. PMID- 4300025 TI - [Research on experimental electrocardiography. II. Action of Myxovirus parainfluenzae type 1 on the ECG of adult rats]. PMID- 4300026 TI - [Research on experimental electrocardiography. 3. Action of Myxovirus parainfluenzae type 1 on the ECG in adult and newborn mice]. PMID- 4300027 TI - [Research of complement fixing antibodies for certain respiratory viruses, Mycoplasma pneumoniae and Coxiella burneti in a community during the first trimester of 1967]. PMID- 4300028 TI - [Pigment and internal diseases]. PMID- 4300030 TI - Development of black down feathering in hybrid chick embryos (cross New Hampshire male with light Sussex female) after pituitary implantation. PMID- 4300029 TI - The effect of nickel chloride on the permeability of the blood-brain barrier. PMID- 4300031 TI - [Papers filled with adsorption media as finished thin-layer plates]. PMID- 4300032 TI - Basic aspects of the interaction of oncogenic viruses with heterologous cells. PMID- 4300033 TI - Surface morphology of frog striated muscle as prepared for and examined in the scanning electron microscope. PMID- 4300034 TI - Are the excitatory nerves to the circular muscle of the guinea-pig ileum cholinergic? PMID- 4300035 TI - Factors affecting vascular responses to haemorrhage in the rat. PMID- 4300036 TI - Noradrenaline as a transmitter in the spinal cord. PMID- 4300037 TI - [Speed of disappearance of plasma renin activity and variations in plasma angiotensin after bilateral nephrectomy in 2 hypertensive patients]. PMID- 4300038 TI - The effect of human growth hormone on growth of patients with hypopituitarism. A combined study. PMID- 4300039 TI - Multiplication of infectious canine hepatitis virus in HeLa cells. PMID- 4300040 TI - [The clinical picture, diagnosis and surgical treatment of hormonal-active tumors of the adrenal cortex]. PMID- 4300041 TI - [The function of the adrenal cortex in thyrotoxicosis]. PMID- 4300043 TI - [Sodium excretion in obese juveniles]. PMID- 4300042 TI - [Pathology of ectopic hormone-producing neoplasms]. PMID- 4300044 TI - Epinephrine: effect on uptake of iodine by dispersed cells of calf thyroid gland. AB - In isolated thyroid cells I-epinephrine (0.1 and 10.0 micrograms per milliliter), norepinephrine and isoproterenol consistently stimulated the accumulation and organic binding of iodine. The effect was partially inhibited by phentolamine, but not propranolol, and hence may be mediated by alpha receptors. Theophylline did not mimic or enhance the epinephrine effect, suggesting that the latter may not result from activation of adenyl cyclase. PMID- 4300045 TI - Brain alcohol dehydrogenase. AB - Significant alcohol dehydrogenase activity has been demonstrated in the soluble fraction of rat brain and is very similar to the liver enzyme in kinetic properties and responses to inhibitors. A cerebral mechanism that oxidizes ethanol may play a significant role in local adjustments during exposure to ethanol and in the pathogenesis of the neural disorders associated with chronic alcohol ingestion or withdrawal. PMID- 4300046 TI - [Pancreatectomy for insuloma]. PMID- 4300048 TI - [Granular cell myoblastoma with pseudocarcinomatous epithelial proliferation of the vocal cord]. PMID- 4300047 TI - [A hygienic study of certain amylolytic enzyme preparations isolated from cultures of molds of the genus Aspergillus]. PMID- 4300049 TI - [The influence of 1 mol MgC12 and 2 mol NaC1 on the inactivation at 50 degrees C of foot-and-mouth disease virus (MKS)]. PMID- 4300050 TI - [Production of high quality interferons by means of strains of smallpox virus, which had been attenuated in cell culture passages]. PMID- 4300051 TI - Culture isolation and identification of clostridia. PMID- 4300052 TI - Congenital cysts of the liver in infancy and childhood. PMID- 4300053 TI - Percutaneous needle aspiration biopsy of the lung. PMID- 4300054 TI - Centrally mediated orthostatic hypotension. Report of cases. PMID- 4300055 TI - The physiology of neuromuscular transmission. PMID- 4300056 TI - Mechanisms of halothane-induced muscle relaxation. PMID- 4300057 TI - Effects of halothane on neuronal tissue. Neurophysiological aspects. PMID- 4300058 TI - Biological properties of a transplantable islet-cell tumor of the golden hamster. 3. Electron microscopic studies. PMID- 4300059 TI - Actions of immobilizing drugs on synaptic transmission. PMID- 4300060 TI - [Changes in the higher nervous activity and behavior of dogs during suboccipital administration of ACTH]. PMID- 4300061 TI - [Effect of reactivators of cholinesterase TMB-4 and 2-PAM on the effectiveness of muscle relaxants]. PMID- 4300062 TI - [Comparative effect of aprolidine and atropine on the toxicity of some phosphoorganic compounds]. PMID- 4300063 TI - [The spectra of electron paramagnetic resonance of blood in workers exposed to the action of phenol vapors]. PMID- 4300064 TI - [Maturation and degranulation of mast cells in the human skin. Electron microscopic studies]. PMID- 4300065 TI - Neuromuscular syndromes associated with carcinoma. PMID- 4300066 TI - Septic arthritis of the knee due to Clostridium welchii. Report of two cases. PMID- 4300067 TI - Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB). AB - A new method for demonstrating cytochrome oxidase activity, based upon the oxidative polymerization of 3,3'-diaminobenzidine (DAB) to an osmiophilic reaction product, has improved the localization of this enzyme over methods based upon the Nadi reaction, in both the light and electron microscopes. The reaction product occurs in nondroplet form, which more accurately delineates the localization of cytochrome oxidase in mitochondria of heart, liver, and kidney. In electron microscopic preparations the excess reaction product is found to overflow into the intracristate spaces and into the outer compartment between inner and outer limiting mitochondrial membranes. This finding suggests that the enzymatic activity of cytochrome c is located on the inner surface of the intracristate space which is the outer surface of the inner mitochondrial membrane. Succinic dehydrogenase activity has also been located at this site by using an osmiophilic ditetrazolium salt, TC-NBT. Considered together, the sites of reactivity of both parts of the respiratory chain have implications for the chemiosomotic hypothesis of Mitchell who suggests a mechanism of energy conservation during electron transport in the respiratory chain of the mitochondrion. PMID- 4300069 TI - Peer group membership of young women with cancer. PMID- 4300068 TI - Unusual aspects of ultrastructural differentiation in rat hepatoma cells. PMID- 4300070 TI - Control of fluid absorption in the renal proximal tubule. AB - Glomerulotubular balance was investigated in isolated, perfused rabbit proximal tubules in vitro in order to evaluate some of the mechanisms proposed to account for the proportionate relationship between glomerular filtration rate and fluid absorption generally observed in vivo. The rate of fluid transport from lumen to bath in proximal convoluted tubules in vitro was approximately equal to the estimated normal rate in vivo. The absorption rate in proximal straight tubules however was approximately one-half as great. If the mechanism responsible for maintenance of glomerulotubular balance is intrinsic to the proximal tubule, as has been proposed on the basis of micropuncture studies, the rate of fluid absorption in vitro should be directly related to the perfusion rate and/or tubule volume. In the present studies absorption rate was only minimally affected when perfusion rate was increased or the tubule distended. Thus, glomerulotubular balance is not mediated by changes in velocity of flow of the tubular fluid or tubular diameter and therefore is not an intrinsic property of the proximal tubule. It has also been proposed that glomerulotubular balance results from a humoral feedback mechanism in which angiotensin directly inhibits fluid absorption by the proximal convoluted tubule. In the present experiments, angiotensin was found to have no significant effect on absorption rate. PMID- 4300071 TI - [Gonadotropin releasing factor in the hypothalamus of female rats]. PMID- 4300072 TI - A method of recording pulmonary ventilation. PMID- 4300073 TI - [Studies on the early symptoms of so-called pancreas head neoplasms]. PMID- 4300074 TI - [Mucosal cancer of the stomach in a 19 year old]. PMID- 4300075 TI - [Current information on the gamma motor system]. PMID- 4300076 TI - [Case of arrhenoblastoma followed by conception shortly after its excision]. PMID- 4300077 TI - [Autoantibodies in mouse strain C3HA with transplanted hepatomas]. PMID- 4300078 TI - [Repeat surgery for recurring thecoma of the ovary]. PMID- 4300079 TI - [Treatment of cancer of the stomach after perforation]. PMID- 4300080 TI - [Puerperal care after discharge from the hospital. Survey on puerperal care in a medium sized city in Tohoku area]. PMID- 4300081 TI - [Home care of the patient following percutaneous ureteral implantation]. PMID- 4300082 TI - [Pregnancy kidney disorders and actual situation of after care - from the health center's viewpoint]. PMID- 4300084 TI - Trends and problems in nursing. PMID- 4300083 TI - The nurses role in intravenous incompatibilities. PMID- 4300085 TI - D.D.S.: cancer detective. PMID- 4300087 TI - [Combined dactinomycin and radiotherapy in the treatment of nephroblastoma of children and its metastases]. PMID- 4300086 TI - [Tissue hormones. A review]. PMID- 4300088 TI - [Synergistic action of antibiotics on Bacillus pyocianaeus]. PMID- 4300089 TI - Sensitivity of herpes simplex virus, vaccinia virus, and adenoviruses to deoxyribonucleic acid inhibitors and thiosemicarbazones in a plaque suppression test. AB - Herpes simplex and vaccinia viruses and adenovirus types 1, 2, 5, and 7 were tested by plaque suppression methods for sensitivity to halogenated deoxyuridines (5-iodo-, 5-bromo-, 5-chloro-, and 5-fluoro-), cytosine arabinoside, isatin-beta thiosemicarbazone, and N-methylisatin-beta-thiosemicarbazone. After incubation for 12 days in HeLa cell cultures, vaccinia virus plaques were still readily suppressed by deoxyribonucleic acid (DNA) inhibitors and thiosemicarbazones. Herpes simplex virus plaques were likewise suppressed by at least three DNA inhibitors. Adenovirus plaques were not suppressed by DNA inhibitors or thiosemicarbazones. 5-Fluoro-2'-deoxyuridine could not be shown to have any antiviral activity, but it did produce a substantial lethal action on the cells. PMID- 4300090 TI - Effect of the route of inoculation on antibody formation in guinea pigs immunized with parinfluenza virus vaccines. AB - The efficiency of the intramuscular route of immunization of guinea pigs was compared with the intraperitoneal route when trivalent parainfluenza virus vaccine was employed as immunogen. When the routes of immunization were compared by effective dose 50, the intramuscular route was more effective. Likewise, a statistical evaluation of conversion rates and of titers revealed significantly higher values for the intramuscular than for the intraperitoneal route to all three components in two of the lots of vaccine tested. PMID- 4300091 TI - Detoxification of liquid cultures of Bordetella pertussis by forced aeration at high pH. AB - Cultures of Bordetella pertussis cultivated in shake flasks were invariably highly toxic for mice, but cultures of the same strain grown in vortex-aerated vessels were nontoxic at the time of harvest. Results reported here indicate that toxin is present during the early log phase in vortex-aerated cultures, but is lost as the cultivation proceeds. The loss of toxicity is apparently due to denaturation of the toxin by the combined influence of vigorous aeration and elevated pH. PMID- 4300092 TI - Clostridium perfringens type A infection of ligated intestinal loops in lambs. AB - Clostridium perfringens type A suspended in fresh medium was injected into ligated intestinal loops of lambs. Within 7 hr after inoculation, the fluid volume of the loops increased up to seven times. No significant accumulation of fluid occurred in loops receiving grown culture, culture supernatant fluid, or medium alone. alpha-Antitoxin injected along with C. perfringens in fresh medium into intestinal loops did not prevent the accumulation of fluid. It is concluded that alpha-toxin plays no major role in C. perfringens type A enteritis. PMID- 4300093 TI - Enhancement of mengovirus nucleic acid infectivity by putrescine. PMID- 4300094 TI - [Preliminary results concerning the study of immunofluorescence as a rapid method for the diagnosis of whooping cough]. PMID- 4300095 TI - [Studies on the sensitivity of some culture media to the inoculation with a minimal number of anaerobic spores. I. Media based on enzymatic digests of animal products]. PMID- 4300096 TI - [Production of interferon in tissue cultures and "in vivo" following infection with Brucella suis]. PMID- 4300097 TI - Studies on the incorporation of 14-C-sodium acetate into the phospholipids of phytohaemagglutinin-stimulated and unstimulated lymphocytes. PMID- 4300098 TI - [Atypical absences in babies and toddlers]. PMID- 4300099 TI - Protein synthesis in nuclei isolated from frozen and thawed mouse liver. PMID- 4300100 TI - Fusion of cells by HVJ: requirement of concentration of virus particles at the site of contact of two cells for fusion. PMID- 4300101 TI - Histotypic self-organization by trypsin-dissociated and EDTA-dissociated chick embryo cells. PMID- 4300102 TI - Biochemistry of shellfish lipids. VII. Occurrence of mannose-6 phosphate in corbicula glycolipid. PMID- 4300103 TI - The origin of hybrid variants derived from subtype strains of foot-and-mouth disease virus. PMID- 4300104 TI - Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells. PMID- 4300105 TI - The effect of 5-fluoro-deoxyuridine on the replication of viral DNA and synthesis of polyoma capsid protein. PMID- 4300106 TI - Influence of animal genotype and age on the amount of circulating interferoh induced by Newcastle disease virus. PMID- 4300107 TI - The use of batch-type zonal ultracentrifuge rotors for the isolation and purification of viruses. PMID- 4300108 TI - Rescue of Rous sarcoma virus in mixed cultures of virogenic mammalian and chicken cells, treated and untreated with Sendai virus and detected by focus assay. PMID- 4300109 TI - Observations on complete and empty capsids of foot-and-mouth disease virus. PMID- 4300110 TI - Analysis of nearest neighbour base frequencies in the RNA of a mammalian virus: encephalomyocarditis virus. PMID- 4300111 TI - Incorporation of labelled phosphate into phospholipids in squid giant axons. PMID- 4300112 TI - Carcinogenic and chronic effects of 4,4'-diaminodiphenylmethane, an epoxyresin hardener. PMID- 4300113 TI - L-Glutamate at insect excitatory nerve-muscle synapses. PMID- 4300114 TI - [On the problem of the so-called pseudosarcoma of the larynx]. PMID- 4300115 TI - [The content and acetylation of tubazid in the lungs of white rats during its administration in combination with ACTH, cortisone and DOCA]. PMID- 4300117 TI - Urinary excretion of steroids by beagle dogs following administration of adrenocorticotrophic hormone. LF-38. PMID- 4300116 TI - [On the irradiation of desoxyribonucleic acids with ultraviolet and visible lights]. PMID- 4300118 TI - Viruses isolated from Beagle dogs exposed to aerosols of 90Sr and 144Ce. LF-36. PMID- 4300119 TI - Evidence for divalent metal sequestration by dog kidney microsomes. SAM-TR-67-88. PMID- 4300120 TI - A method for digital calculation of absolute free radical concentrations. NADC-MR 6804. PMID- 4300121 TI - [Effect of NAD-H2 and sodium ascorbate on corticosteroid biosynthesis in homogenates of pig adrenal cortex]. PMID- 4300122 TI - [A case of malignant synovioma of unusual localization]. PMID- 4300123 TI - [Enzyme histochemical and radioautographic studies during cancerization of the rat liver with diethylnitrosamine]. PMID- 4300124 TI - [Various pathophysiologic peculiarities of depressive states]. PMID- 4300125 TI - Giant retroperitoneal mucocele simulating pseudomyxoma peritonei and mucinous adenocarcinoma. PMID- 4300126 TI - Studies in viral respiratory infections among Finnish servicemen. PMID- 4300127 TI - A gastric factor in the pathogenesis of the Zollinger-Ellison syndrome. PMID- 4300129 TI - Surgical abnormalities in urachus remnants in adults. PMID- 4300128 TI - Identification of the diarrheogenic hormone associated with non-beta islet cell tumors of the pancreas. PMID- 4300130 TI - Alveolar proteinosis. Its experimental production in rodents. PMID- 4300131 TI - Human herpesvirus infection. Its fine structure identification in paraffin embedded tissue. PMID- 4300132 TI - Hepatocarcinoma associated with biliary cirrhosis. A case due to congenital bile duct atresia. PMID- 4300133 TI - [Pathological diagnosis of muscular diseases. (2)]. PMID- 4300134 TI - Hydroxysteroid dehydrogenase activity in human skin. I. Histochemical techniques for the demonstration of 3-beta-hydroxysteroid dehydrogenase, and a method for the semiquantitation of its activity. PMID- 4300135 TI - Effects of physostigmine on the afterdischarge and slow postsynaptic potentials of bullfrog sympathetic ganglia. AB - 1. The effects of anticholinesterases (anti-ChEs) (physostigmine, prostigmine and TEPP) on the afterdischarges and the extracellular and intracellular slow potentials of bullfrog sympathetic ganglia were studied.2. The anti-ChEs augmented the early afterdischarge, the late negative potential and the slow excitatory postsynaptic potential. This indicated that the nature of the early afterdischarge was cholinergic (muscarinic) and that the late negative potential or the slow excitatory postsynaptic potential generated the early afterdischarge.3. Since the anti-ChEs increased the positive potential, the depression of the early afterdischarge observed in the presence of an antiChE was explained to be caused by the increased inhibitory effect of the enhanced positive potential.4. Prostigmine and tetraethyl pyrophosphate did not show any appreciable effects on the late afterdischarge, the late late negative potential nor the late slow excitatory postsynaptic potential. This indicated that the nature of the late afterdischarge was non-cholinergic and that the late late negative potential or the late slow excitatory postsynaptic potential generated the late afterdischarge.5. Physostigmine reversibly depressed the late afterdischarge, the late late negative potential and the late slow excitatory postsynaptic potential. The depressant action of physostigmine was not due to its anti-ChE action. PMID- 4300136 TI - Bioassay of long duration corticotrophin preparations on guinea-pigs. PMID- 4300137 TI - Enzymatic assay of the prostaglandins. PMID- 4300138 TI - Presence and properties of dihydrofolate reductases within the genus Trypanosoma. PMID- 4300139 TI - Cyclic AMP as a mediator of hormonal metabolic effects in brown adipose tissue. PMID- 4300140 TI - Anti-arrhythmic ancd local anaesthetic activity of some beta-receptor blocking compounds. PMID- 4300141 TI - Adrenergic mechanisms in hypertension. PMID- 4300142 TI - Metabolic actions associated with stimulation of alpha- and beta-receptors for adrenaline in smooth muscle. PMID- 4300143 TI - Electromyography in the diagnosis and treatment of myasthenia gravis. PMID- 4300144 TI - The effect of chlorpromazine on cerebral glucose, ATP, ADP, AMP and ATPase in the mouse. AB - 1. Administration of chlorpromazine 10 mg/kg intraperitoneally to mice produced no alteration in cerebral adenosine triphosphate (ATP), adenosine diphosphate (ADP) or adenosine monophosphate (AMP). In these animals there was an increase in the glucose content of the supernatants of homogenates of liver and brain following acid hydrolysis.2. Chlorpromazine 40 mg/kg intraperitoneally did not affect Mg(++) activated adenosine triphosphatase (ATPase) activity in the brain. PMID- 4300145 TI - Changes in the adrenocortical cells of bullfrogs following hormonal stimulation. PMID- 4300146 TI - Steroid responses to ACTH-like polypeptides. PMID- 4300147 TI - Medullary carcinoma of the thyroid--a cause of Cushing's syndrome: report of two cases. PMID- 4300148 TI - Limb regeneration in Ambystoma larvae during and after treatment with adult pituitary hormones. PMID- 4300149 TI - Differentiation of nerve terminals in the crayfish opener muscle and its functional significance. AB - Junctional potentials (jp's) recorded from superficial distal fibers of the crayfish opener muscle are up to 50 times larger than jp' in superficial central fibers when the single motor axon that innervates the muscle is stimulated at a frequency of 1/sec or less. At 80/sec, in contrast, central jp's are up to four times larger than those observed in distal fibers. The tension produced by single muscle fibers of either type is directly proportional to the integral of the time voltage curve minus an excitation-contraction coupling threshold of 3 mv. Distal fibers therefore produce almost all the total muscle tension at low frequencies of stimulation and central fibers add an increasingly greater contribution as their nerve endings begin to facilitate in response to increased rate of motor discharge. Differentiation of muscle membrane characteristics (input resistance, space constant, time constant) cannot account for these differences in facilitation ratios. The mechanism of neuronal differentiation is not based upon the size or effectiveness of transmitter quanta, since equal sized jp's have equal variances;: mjp sizes and variances are also equal. No differences were found between fiber types in rates of transmitter mobilization, density of innervation, or the relationship between transmitter release and terminal depolarization. Single terminals on distal fibers were found to release transmitter with a greater probability than central terminals. More effective invasion of distal terminals by the nerve impulse at low frequencies can account for the difference. PMID- 4300151 TI - An immuno-cytopathogenic interaction between sensitized leukocytes and epithelial cells carrying a persistent noncytocidal myxovirus infection. PMID- 4300150 TI - Isolated epithelial cells of the toad bladder. Their preparation, oxygen consumption, and electrolyte content. AB - Epithelial cells of the toad bladder were disaggregated with EDTA, trypsin, hyaluronidase, or collagenase and were then scraped free of the underlying connective tissue. In most experiments EDTA was complexed with a divalent cation before the tissue was scraped. Q(OO2), sucrose and inulin spaces, and electrolytes of the isolated cells were measured. Cells disaggregated by collagenase or hyaluronidase consumed O(2) at a rate of 4 microl hr(-1) dry wt( 1). Q(OO2) was increased 50% by ADH (100 U/liter) or by cyclic 3',5'-AMP (10 mM/liter). Na(+)-free Ringer's depressed the Q(OO2) by 40%. The Q(OO2) of cells prepared by trypsin treatment or by two EDTA methods was depressed by Na(+)-free Ringer's but was stimulated relatively little by ADH. Two other EDTA protocols produced cells that did not respond to Na(+) lack or ADH. The intracellular Na(+) and K(+) concentrations of collagenase-disaggregated cells were 32 and 117 mEq/kg cell H(2)O, respectively. Cation concentrations of hyaluronidase cells were similar, but cells that did not respond to ADH had higher intracellular Na(+) concentrations. Cells unresponsive to ADH and Na(+) lack had high sucrose spaces and low transcellular membrane gradients of Na(+), K(+), and Cl(-). The results suggest that trypsin and EDTA disaggregation damage the active Na(+) transport system of the isolated cell. Certain EDTA techniques may also produce a general increase in permeability. Collagenase and hyaluronidase cells appear to function normally. PMID- 4300152 TI - Neutralizing activity in nasal secretions and serum in resistance of volunteers to parainfluenza virus type 2. PMID- 4300153 TI - A new measure of the sensitivity of electron spin resonance spectrometers. PMID- 4300155 TI - [Current drug therapy of organic hypoglycemia]. PMID- 4300154 TI - [Adenoma of the islands of Langerhans and pregnancy. (Apropos of 2 cases)]. PMID- 4300156 TI - [Severe hypoglycemia in a woman with pituitary adenoma and adenoma of the islands of Langerhans]. PMID- 4300159 TI - Common codon characteristic of aminoacids capable to antagonize the antipolio action of guanidine and d-penicillamine. PMID- 4300157 TI - Method for measuring hormonal effects on conversion of adenosine triphosphate to adenosine 3', 5'-monophosphate by isolated lipocytes. PMID- 4300158 TI - Phosphorylase activity and glycogen levels in the adrenal cortex of rats subjected to acute ACTH stimulation. PMID- 4300160 TI - [Deep electrical burn complicated by anuria and Pseudomonas aeruginosa sepsis]. PMID- 4300161 TI - The value of the angiotensin infusion test in the diagnosis of true renovascular hypertension. PMID- 4300162 TI - Renal carcinoma. A 10-year study. PMID- 4300163 TI - Spectrophotometric determination of serum magnesium by eriochrome black T. PMID- 4300164 TI - Measurements of thallium in biologic materials by atomic absorption spectrometry. PMID- 4300165 TI - A comparison of properties of renin obtained from the kidney and uterus of the rabbit. PMID- 4300167 TI - Abolition of circadian periodicity of plasma 17-OHCS levels in the cat. PMID- 4300166 TI - Myogenic transmission of antral slow waves across the gastroduodenal junction in situ. PMID- 4300168 TI - Enhancement of parainfluenza 2 virus hemagglutinin. AB - A comparison was made of the three previously described methods of enhancement of parainfluenza 2 virus hemagglutinin (HA): ultrasonic oscillation, adsorption to erythrocytes and elution (AE), and Tween-ether (TE) treatment. TE treatment resulted in the maximal elevation of HA titer, complete loss of infectivity, and the maximal loss of heat stability of HA. Ultrasonic oscillation caused the least elevation of HA titer, minimal loss of infectivity, and the least loss of heat stability of both HA and infectivity. The effect of AE remained intermediate. It is suggested that the changes produced by these three methods are varying degrees of disruption of virus particles. Growth studies on parainfluenza 2 virus are also presented. PMID- 4300169 TI - Production of nuclease-formine 5'-nucleotide by Aspergillus quercinus in a low phosphate medium. AB - The production of ribonucleic acid (RNA)-depolymerase-forming 5'-nucleotides (5' nuclease) was investigated with the fungus Aspergillus quercinus in media containing 68, 10, 5, 3, 1, and 0.5 mg of phosphorus per 100 ml. Yields were maximal with 5 mg of phosphorus per 100 ml. RNA-depolymerase-forming 3' nucleosides (3'-nuclease) and phosphomonoesterase were maximal in media containing 1 and 0.5 mg of phosphorus per 100 ml. The 5'-nuclease was purified approximately 530-fold with a recovery of 84% by column chromatography on diethylaminoethyl-cellulose and by gel filtration through Sephadex G-100. The purified enzyme was capable of acting on both deoxyribonucleic acid and RNA, and the 5'-mononucleotides produced were identified by paper chromatography. The enzyme 5'-nuclease appears to be one of the repressible exonucleases that are active in the production of 5'-mononucleotides. PMID- 4300170 TI - Rhinovirus plaque formation in WI-38 cells with methylcellulose overlay. AB - A sensitive, reliable plaque assay system is described for five rhinoviruses using freshly prepared methylcellulose overlay and human embryonic diploid cells. Circular plaques with irregular edges, 2 mm in size, were formed by rhinoviruses 1A, 2, 6, and 13 after 6 or 7 days of incubation. A fifth rhinovirus, 17, formed a 1- to 2-mm feather plaque after 14 days of incubation. Plaque counts of rhinoviruses 1A and 13 were not affected by varying the pH of the overlay from 6.9 to 7.5. Plaque sizes and plaque-forming unit values of high passage rhinoviruses 1A and 13 were equivalent when tested at 26, 31, or 36 C. The rhinoviruses tested were sensitive to incubation at 40 C or heating at 50 C. Enhancement of plaques was observed when Mg(++) was incorporated into agar overlays, but enhancement did not occur when Mg(++) was added to methylcellulose overlays. PMID- 4300174 TI - [Experimental contribution to the knowledge of dermatitis pustulosa in sheep. IV. The cultivation of the dermatitis pustulosa virus in tissue culture]. PMID- 4300171 TI - Survey of microorganism for the production of extracellular phytase. AB - A culture enrichment technique was used to isolate phytase-producing microorganisms. Also, microorganisms from various culture collections were tested for their phytase-producing ability. A number of the Aspergillus niger group produced extracellular phytase which dephosphorylated calcium phytate in acidic solution. A soil isolate, A. ficuum NRRL 3135, produced the most active phytase in a cornstarch-based medium. Production of phytase was strongly repressed by inorganic phosphates and required a high carbon to phosphorus ratio in the medium. PMID- 4300173 TI - Lecithinase production by Clostridium perfringens in chemicallly defined media. PMID- 4300172 TI - Appearance of mouse-lethal toxin in liquid cultures of Bordetella pertussis. AB - The mouse-lethal toxin present in liquid cultures of most smooth strains of Bordetella pertussis is known to originate in the cytoplasm of the organism but to be most lethal for mice when released into the supernatant fluid. It is also recognized that cell degeneration and lysis occur in liquid cultures during the stationary and decline phases of growth. For these reasons, it is generally believed that most of the toxicity demonstrable in liquid cultures at the time of harvest is released during the later stages of cultivation, when high alkalinity and aging of cells favor lysis. However, the results reported here have indicated that high levels of mouse-lethal toxicity arise during very early log phase and that the peak of toxicity is reached before the end of the log phase. No further increase in toxicity was observed during stationary and decline phases. The very early appearance of toxicity could not be explained by the presence in the inoculum of a proportion of dead and degenerating cells, and it is concluded that the toxin is produced mainly by actively growing cells. This was confirmed by tests on organisms growing in continuous culture. Electron-microscopic examination of cells from a very early log-phase culture revealed the presence of large numbers of small vesicles on the cell walls of about 5% of the population. It is suggested that these vesicles may be associated with the releases of toxin from living cells. It is concluded that no useful reduction in the toxicity of cultures would result from harvesting before the end of the log phase of growth. PMID- 4300175 TI - [Experimental contribution to the knowledge of dermatitis pustulosa in sheep. 8. The determination of precipitating antigen in the pustular material by means of the agar gel test]. PMID- 4300177 TI - [Light and electron microscopic studies of a new bovine herpesvirus]. PMID- 4300176 TI - [Experimental contribution to the knowledge of dermatitis pustulosa in sheep. IX. The detection of the relations of the dermatitis pustulosa virus to other viruses of the variola group by means of the complement binding reaction and the agar gel test]. PMID- 4300178 TI - [Isolation and identification of another new bovine herpesvirus]. PMID- 4300179 TI - [Immunofluorescent studies with the viruses of infectious bovine rhinotracheitis and bovine herpes in calf kidney cell cultures]. PMID- 4300180 TI - [Tumors of the carotid corpuscle]. PMID- 4300181 TI - Studies on human angiotensin. PMID- 4300183 TI - Evidence for humoral factors participating in the renin-substrate reaction. PMID- 4300182 TI - Kinetics of renin-renin substrate. PMID- 4300184 TI - Individualities of vascular smooth muscles in response to angiotensin. PMID- 4300186 TI - Composition of tubular fluid in the macula densa segment as a factor regulating the function of the juxtaglomerular apparatus. PMID- 4300185 TI - Mechanisms involved in the progressive pressor response to very small amounts of angiotensin in conscious rabbits. PMID- 4300187 TI - Studies on the preparation and properties of renin. PMID- 4300188 TI - Relationship between intrarenal hydrostatic pressure and hemodynamically induced changes in sodium excretion. PMID- 4300189 TI - The metabolic fate of vitamin D3-3H in chronic renal failure. AB - The absorption and metabolism of vitamin D(3)-(3)H was studied in eight patients with chronic renal failure. Although the intestinal absorption of vitamin D(3) (3)H was normal, the metabolic fate of the vitamin was abnormal as characterized by a twofold increase in fractional turnover rate, an abnormal accumulation of biologically inactive lipid-soluble metabolites, and the urinary excretion of both vitamin D(3)-(3)H and biologically inactive metabolites. Neither alterations in water-soluble vitamin D(3) metabolites nor qualitative abnormalities in protein-binding of vitamin D(3) were observed in the uremic subjects. Although hemodialysis proved ineffectual in reversing the observed abnormalities in vitamin D(3) metabolism and excretion, renal homotransplantation was completely successful in this regard. These experiments support the conclusion that the resistance to therapeutic doses of vitamin D often seen in patients with chronic renal failure and renal osteodystrophy results from an acquired defect in the metabolism and excretion of vitamin D. PMID- 4300190 TI - Pulmonary capillary thrombosis in septicemia due to gram-positive bacteria. PMID- 4300191 TI - [Enzyme histochemistry. An introduction]. PMID- 4300192 TI - [On a method of studying the structure of the stomach wall in cancer]. PMID- 4300193 TI - [The effect of dichlorodiphenyldichloroethane on transplanted animal tumors]. PMID- 4300195 TI - [On the antigenic specificity of experimental rat tumors]. PMID- 4300194 TI - [The development of the viral theory of tumor origin]. PMID- 4300196 TI - [Morphologic changes in tissue cultures of chick fibroblasts inoculated with Rous virus]. PMID- 4300198 TI - [Diagnostic possibilities of lymphography in tumors of the urinary bladder]. PMID- 4300197 TI - [The effect of disordered thyroid gland function on metastatic Brown-Pearce tumors]. PMID- 4300199 TI - [The tumor cell in tissue culture: eaneerogenesis and biological characteristics (progress and achievements during the years of Soviet rule)]. PMID- 4300200 TI - [On the radiosensitivity of mixed tumors of the parotid gland]. PMID- 4300201 TI - [The effect of thymectomy on the growth of Rous sarcoma in chicks]. PMID- 4300202 TI - [Rous sarcoma virus isolated from tumors developing in chicks after administration of 9, 10-dimethyl-1,2-benzanthracene (DMBA)]. PMID- 4300203 TI - [Histochemical detection of various energy metabolism enzymes in tumors with various growth rates]. PMID- 4300204 TI - [The study of the disorder of tooth development in mice of a mutant line of microphthalmia]. PMID- 4300205 TI - [Clinical and experimental studies on iron metabolism in young tumor-bearing subjects. 3. Non-hemin iron ratio in malignant tissue and principal organs in pediatric patients with malignant tumors]. PMID- 4300206 TI - Search for perinatal viral infection. A prospective, clinical, virologic, and serologic study. PMID- 4300208 TI - Visceral involvement by herpes simplex virus in eczema herpeticum. PMID- 4300207 TI - Viral infections in hospitalized neonates. PMID- 4300209 TI - Niridazole in amebic dysentery and hepatic amebiasis. PMID- 4300210 TI - A clinical trial of thiabendazole in strongyloidiasis. PMID- 4300211 TI - Ceruminoma. PMID- 4300212 TI - [A case of linitis plastica]. PMID- 4300213 TI - [On testicular neoplastic pathology in old men: apropos of 2 seminomas and 1 embryonal carcinoma in men in their seventies]. PMID- 4300214 TI - [Syndactyly and polydactyly: genetic and surgical problems]. PMID- 4300215 TI - [Current status of the struggle against Pseudomonas aeruginosa]. PMID- 4300216 TI - Cytomegalovirus disease presenting as hepatitis. PMID- 4300217 TI - Evidence suggesting a relationship between polyoma virus-induced transplantation antigen and normal embryonic antigen. PMID- 4300218 TI - Electron microscopic studies of radiation-induced leukemia in mice: virus release following total-body x-ray irradiation. PMID- 4300219 TI - Effects of hydroxyurea on polyoma virus replication. PMID- 4300220 TI - Role of the mammary tumor virus in the immunogenicity of spontaneous mammary carcinomas of BALB/c mice and in the responsiveness of the hosts. PMID- 4300222 TI - Carcinogenesis by avian sarcoma viruses. PMID- 4300221 TI - The role of the viral genome in oncogenesis. PMID- 4300223 TI - A possible role of transfer RNA in the mechanism of carcinogenesis. PMID- 4300224 TI - Metabolic regulation and enzyme alterations in the Morris hepatomas. PMID- 4300225 TI - Summary of discussion on neoplasms. PMID- 4300226 TI - [Study on early breast cancer]. PMID- 4300227 TI - Compression of digital nerves by Pacinian corpuscles. A report of two cases. PMID- 4300229 TI - Fatal herpesvirus hominis (herpes simplex virus) infections in children. Clinical, pathologic, and virologic characteristics. PMID- 4300228 TI - Familial fatal varicella. PMID- 4300230 TI - Hemodynamic balance and the kidney. PMID- 4300231 TI - [Carcinoma of the rectum and sigmoid with metastases into the ovaries (Krukenberg tumor)]. PMID- 4300232 TI - [The technique of operative roentgenomanometry of the biliary tract]. PMID- 4300233 TI - [Function of the adrenal in rheumatic heart disease]. PMID- 4300234 TI - [Surgical treatment of adrenal gland tumors]. PMID- 4300235 TI - [Lymphography and intralymphatic infusion of drugs in oncological clinical practice]. PMID- 4300236 TI - [Amyloidosis of the oral cavity and pharynx]. PMID- 4300237 TI - Acute polyneuritis requiring artificial respiration. PMID- 4300238 TI - [Pleomorphic adenomas of the submandibular and sublingual salivary gland]. PMID- 4300239 TI - [Pleomorphic adenomas of the small salivary glands]. PMID- 4300240 TI - Salivary gland tumors occurring after radiation of the head and neck area. PMID- 4300242 TI - In vivo activity of an inhibitor of influenza virus-induced ribonucleic acid polymerase. PMID- 4300241 TI - Tumors of the deep lobe of the parotid gland. PMID- 4300243 TI - Newer aspects of glucose fermentation in cancer growth and control. PMID- 4300244 TI - Subcellular distribution of monoamine oxidase activity in rat liver and vas deferens. PMID- 4300245 TI - [Curare block of the posterior cricoarytenoid muscle and the diaphragm in relation to respiratory innervation]. PMID- 4300246 TI - Infusion of liver tumours. PMID- 4300248 TI - Oncogenic action of bovine papilloma virus in hamsters. PMID- 4300247 TI - Rate of inactivation of smallpox and vaccinia viruses by fixatives used in histological methods. PMID- 4300249 TI - [Report from Man, Ivory Coast]. PMID- 4300250 TI - The bloodless greater omentum for myocardial revascularization. PMID- 4300251 TI - Inappropriate antidiuretic hormone secretion in carcinoma of the lung. PMID- 4300252 TI - Effects of aflatoxin B1 and other carcinogens upon nucleolar RNA of various tissues in the rat. PMID- 4300253 TI - Parallel orientation of fibroblasts in vitro. PMID- 4300255 TI - [The explanted cancer cell]. PMID- 4300254 TI - [Pharmacological and biochemical properties of pyridylethylhydrazines and pyridylethylamines]. PMID- 4300256 TI - [Collagenase in cells of highly developed animals]. PMID- 4300257 TI - Effect of long term in vivo application of phenanthroline. Penicillamine and further chelating agents on the synthesis of collagenous and non-collagenous proteins in fibrotic liver and wound granulation tissue. PMID- 4300259 TI - Administrative implications of small group experiences. PMID- 4300258 TI - Enzyme activities in liver, muscle, and adipose tissue of calves and steers. PMID- 4300260 TI - The nurse's role in the informal group. PMID- 4300261 TI - Factors in interpersonal and family relationships and alcoholism. PMID- 4300262 TI - Patients speak out. PMID- 4300263 TI - Occupational therapy demonstration for nursing students. PMID- 4300264 TI - Musical rhythm motivation. PMID- 4300265 TI - Psychiatric drugs and trends. The National Coordinating Council on Drug Abuse Education and Information. PMID- 4300266 TI - Geriatrics. Soviet Union. PMID- 4300267 TI - The use of the pressor assay of renal venous blood in evaluation of renal hypertension. PMID- 4300268 TI - [Studies of 2-mercaptoethanol sensitivity of the antisera against Japanese encephalitis virus. 4. Relationship between inoculum size and antibody production in artificially inoculated swine]. PMID- 4300269 TI - [Differential diagnosis of malignant and benign thyroid tumors]. PMID- 4300270 TI - [Insulinoma]. PMID- 4300271 TI - [Diagnosis and study of the mode of transmission of varicella by the fluorescent antibody technic]. PMID- 4300273 TI - [Criteria for identification of Clostridium welchii. 4. Sporulation]. PMID- 4300272 TI - [Cytomegaloviruria among healthy children in a nursery school]. PMID- 4300274 TI - Functioning tumors of the pancreas. PMID- 4300276 TI - Our nurses are nursing. PMID- 4300275 TI - [The histological criterion in prognosis of mammary cancer]. PMID- 4300277 TI - [A tumor from arteriovenous anastomoses in the lung]. PMID- 4300278 TI - [Free radicals in the tissue of sarcomas]. PMID- 4300279 TI - [On the cytological diagnosis of malignant tumors of the distal region of the large intestine]. PMID- 4300280 TI - [The combined effect of stress reactions and extracts of Eleutherococcus on the inoculation of tumor cells by intravenous administration]. PMID- 4300281 TI - [Resection of the humerus in metastasis of a hydronephroma]. PMID- 4300282 TI - [Bronchitis and the pneumonic syndrome. 32. Pathological anatomy of the pneumonic syndrome]. PMID- 4300283 TI - [On the problem of the status of neuromuscular transmission in myotonic disease]. PMID- 4300284 TI - [On the characteristics of energy metabolism in neurons and glial cells (review of the literature)]. PMID- 4300285 TI - Change in the phage type of Staphylococcus aureus as a result of lysogenizatio. PMID- 4300286 TI - Comparative study on the interferon production by the leukocytes of healthy and leukaemic subjects. PMID- 4300287 TI - Performance characteristics of dust respirators, bureau of mines approved and non approved types. PMID- 4300288 TI - Fibrous and mineral content of cosmetic talcum products. PMID- 4300289 TI - Nature of anaemia in rheumatoid arthritis. IX. Folate metabolism in patients with rheumatoid arthritis. PMID- 4300290 TI - Primary structure of insoluble tendon collagen. II. N- and C-terminal positional analysis of collagenolytic breakdown products of trypsin-pretreated collagen. PMID- 4300291 TI - Respiratory mechanisms in the Flexibacteriaceae. I. Studies on the terminal oxidase system of Leucothrix mucor. PMID- 4300293 TI - Primary structure of insoluble tendon collagen. I. N- and C-terminal positional analysis of collagenolytic breakdown products of native collagen. PMID- 4300292 TI - Cellular membranes: the isolation and characterization of the plasma and smooth membranes of HeLa cells. PMID- 4300294 TI - Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. I. Incorporation of choline into phosphatidylcholine of mitochondria and other membranous structures and effect of metabolic inhibitors. PMID- 4300295 TI - Cryoglobulinemic neuropathy. Incidence and clinical characteristics. PMID- 4300296 TI - Vertigo. An explanation--labyrinthine arrhythmia. PMID- 4300298 TI - [Adrenal cortex]. PMID- 4300297 TI - Endocrine abnormalities in bronchial carcinoma. PMID- 4300299 TI - [ACTH or adrenocortical hormone therapy in myasthenia gravis, myotonia and herpes zoster]. PMID- 4300300 TI - Respiratory disease in children caused by parainfluenza viruses. Description of an acute outbreak. PMID- 4300301 TI - Slowly evolving widespread diffuse alimentary tract carcinoma (linitis plastica). PMID- 4300303 TI - Kinetic and equilibrium study of the adsorption of 2,4-dichlorophenoxy acetic acid on some surfaces. PMID- 4300304 TI - Metabolic basis of aminonucleoside nephrosis in rats. I. Inhibition of alpha oxoglutarate oxidation by aminonucleoside. PMID- 4300302 TI - Incidence of primary carcinoma of the liver in the west of Scotland between 1949 and 1965. PMID- 4300305 TI - Excretion of catecholamine catabolites by normal children. PMID- 4300306 TI - Radioimmunoassay of angiotensin. PMID- 4300307 TI - New enzymatic method for measurement of paraldehyde: correlation of effects with serum and CSF levels. PMID- 4300308 TI - Dietary factors and hepatoma in rainbow trout (Salmo gairdneri). I. Aflatoxins in vegetable protein feedstuffs. PMID- 4300309 TI - Study of the antigenic specificity of Graffi leukemic cells. PMID- 4300310 TI - Resistance to small amounts of Bittner mammary tumor virus in offspring of C57BL female mice with the virus. PMID- 4300311 TI - Pyeloplasty by modified ureteroneopyelostomy. PMID- 4300313 TI - Systemic lupus erythematosus complicated by coccidioidomycosis. PMID- 4300312 TI - Evaluation of polymyxin catheter lubricant and impregnated catheters. PMID- 4300314 TI - [Ascites attractant of ascites hepatoma]. PMID- 4300316 TI - Mechanism of regression of tumours induced by polyoma virus in rabbits. PMID- 4300315 TI - [Radioisotope scanning in the diagnosis of cancer]. PMID- 4300317 TI - A foot and mouth disease syndrome in pigs caused by an enterovirus. PMID- 4300318 TI - Functional interactions between biogenic amines, 3',5'-cyclic AMP and manganese. PMID- 4300319 TI - Age variations of acid deoxyribonuclease activity in mouse liver nuclei. PMID- 4300321 TI - [Effects of various diseases on the hemodynamics of the fingers]. PMID- 4300320 TI - The effect of tranylcypromine on synthesis of macromolecules and enzyme activities in neurons and glia. PMID- 4300322 TI - [4 cases of oculodentodigital syndrome]. PMID- 4300324 TI - Urinary bladder opacification following lymphangiography. PMID- 4300323 TI - [Cyto-chemical detection of phosphatase activity by electron microscopy]. PMID- 4300325 TI - [Studies on plasma angiotensinase. Hypertension and plasma angiotensinase]. PMID- 4300326 TI - [Three treated cases of congenital cystoma of the common bile duct and the analysis of the cases in Japan]. PMID- 4300327 TI - [Local administration of polymyxin B in the field of urology]. PMID- 4300328 TI - Patient isolator systems in cancer chemotherapy. The use of high-dose "nonabsorable" antibiotics in the reduction of bowel flora. PMID- 4300330 TI - Cure of adult Wilms' tumor with distant metastasis? A case report. PMID- 4300329 TI - Second primary neoplasms in children. PMID- 4300332 TI - Kinetic studies of temperature changes and oxygen uptake concomitant with substrate oxidation by mitochondria: the enthalpy of succinate oxidation during ATP formation by mitochondria. PMID- 4300331 TI - Membrane systems of mitochondria. VI. Membranes of liver mitochondria. PMID- 4300333 TI - [Can the carrier of active materials in dragees have a teratogenic effect]. PMID- 4300335 TI - [3. Kinetics of changes of free radical content in the development of ascitic sarcoma 37]. PMID- 4300334 TI - Electroencephalographic changes after intravenous administration of antibiotics. PMID- 4300336 TI - [Test for ACTH-secreting capacity using synthetic lysine-8-vasopressin and metopirone]. PMID- 4300337 TI - [On the adrenocortical reserve test for infants using synthetic ACTH]. PMID- 4300338 TI - [Limited experience in adrenocortical function tests in infants]. PMID- 4300339 TI - The plain chest radiograph in seventy-five cases of primary carcinoma of the liver. PMID- 4300340 TI - [Suppression of viral and chemical carcinogenesis by artificial heterogenization]. PMID- 4300341 TI - [Clostridium perfringens spheroplasts and their ability to synthesize proteins of the exoantigenic complex]. PMID- 4300342 TI - [Toxic reactions during treatment with viomycin in pulmonary tuberculosis]. PMID- 4300344 TI - [Studies on the effect of a porphyrinogenic agent (DDC) on hepatoma cells]. PMID- 4300343 TI - [Localization of enzymes and biological activity in bacterial cell envelope]. PMID- 4300345 TI - [Studies in neuroradiography]. PMID- 4300346 TI - [Studies on the nervous control of the salt composition of saliva in the dog. First report. Electrophysiological studies on the activities of the so-called salt nerve]. PMID- 4300347 TI - Reflex potentials of the vagus nerve at various levels evoked by stimulations of various peripheral nerves. PMID- 4300348 TI - Wilms' tumor and congenital aniridia. PMID- 4300349 TI - [Aldosterone and the juxtaglomerular system in some forms of symptomatic hypertension]. PMID- 4300350 TI - Studies of bacterial susceptibility of heart valves. PMID- 4300351 TI - [Hemagglutination inhibition antibody and 2-mercapto-ethanol sensitive antibody to Japanese encephalitis in canine serum]. PMID- 4300352 TI - Effects of coffee ingestion on oral glucose tolerance curves in normal human subjects. PMID- 4300354 TI - [Frey's syndrome]. PMID- 4300353 TI - Blood pyruvate and lactate during febrile human infections. PMID- 4300355 TI - [Hunt's syndrome]. PMID- 4300356 TI - [Urinary excretion of 5-hydroxyproline in lung cancer]. PMID- 4300357 TI - [Distribution of the nonspecific phosphomonoesterases in the spinal cord of the chicken]. PMID- 4300358 TI - [On the sex specific differences in the enzyme pattern of the rat]. PMID- 4300359 TI - [Comparative histochemical studies on the phosphatase content of capillaries]. PMID- 4300360 TI - [DPNH-diaphorase detection in the preimplantation stages in rodents]. PMID- 4300361 TI - Effects of genetic cellular resistance on cell transformation and virus replication in chicken hematopoietic cell cultures infected with avian myeloblastosis virus (BAI-A). PMID- 4300362 TI - Replication of Sendai virus. I. Comparison of the viral RNA and virus-specific RNA synthesis with Newcastle disease virus. PMID- 4300363 TI - A genetic map of poliovirus temperature-sensitive mutants. PMID- 4300364 TI - Induction with hydroxylamine of guanidine resistance in poliovirus. PMID- 4300366 TI - [Contribution to the cytology of bronchiolo-alveolar cancers]. PMID- 4300365 TI - Enzyme-histochemical studies on the hypothalamus with specil reference to the supraoptic and paraventricular nuclei of squirrel monkey (Saimiri sciureus). PMID- 4300367 TI - A complement fixing antigen from an M rhinovirus (brief report). PMID- 4300368 TI - Two types of morphological transformation of bovine kidney cells infected in vitro with SV40. PMID- 4300369 TI - The effect of trauma on production of herpes interferon in guinea pigs. PMID- 4300370 TI - Intestinal pain. Participation of other visceral sensations. PMID- 4300372 TI - [The use of laser microsonde in otosclerosis research]. PMID- 4300373 TI - [On the pathogenesis of viral infections in ENT field]. PMID- 4300376 TI - [On the malignancy degree of recurrent parotid tumors]. PMID- 4300374 TI - [Histochemical enzyme studies of laryngeal muscles of the human]. PMID- 4300375 TI - [Clinical evaluation of tryptophan demonstration in the salivary glands]. PMID- 4300371 TI - [Treatment with antibiotic agents with special reference to their relation to otorhinolaryngology]. PMID- 4300377 TI - [On amyloidosis of the upper respiratory tract]. PMID- 4300378 TI - Inhibition of mitochondrial electron transport by piericidin A and related compounds. PMID- 4300379 TI - The inhibition of microsomal glucose 6-phosphatase by metal-binding agents. PMID- 4300380 TI - Effects of the solvent medium on polyvalylribonuclease aggregation. PMID- 4300381 TI - [Separation of pea seedling mitochondria from chloroplast fragments by density gradient centrifugation]. PMID- 4300382 TI - [Some characteristics of fructosediphosphatase from loach embryo]. PMID- 4300383 TI - [Localization of inorganic polyphosphates and nucleoside polyphoshates in cells of yeast Endomyces magnusii]. PMID- 4300384 TI - [On the catalytic functions of peroxidase]. PMID- 4300385 TI - [Concerning the inactivation of glyceraldehyde-3-phosphate dehydrogenase]. PMID- 4300386 TI - [Interaction of histomes with phosphoproteins and some other phosphorus containing compounds]. PMID- 4300387 TI - [Dephosphorylation of glucosamine-6-phosphate in rat liver homogenates. IV]. PMID- 4300388 TI - [Paget's disease of the breast developing over a 2 year period in an 82-year-old woman]. PMID- 4300389 TI - [Abdominal cutaneous gangrene after aortography]. PMID- 4300390 TI - [Comparative action of phospholipases A and C on NADH2-oxidase systems and succinate-oxidase of myocardium]. PMID- 4300391 TI - [Action of phospholipids A and C on lipids obtained from sub-mitochondrial preparations]. PMID- 4300392 TI - [Action of phospholipases A and C on the succinate-cytochrome c reducatase system of myocardium]. PMID- 4300393 TI - Pharmacologic actions of tetrodotoxin studied by direct perfusion of the sinus node. PMID- 4300394 TI - Isolation from a salivary gland of granules containing renin and kallikrein. PMID- 4300395 TI - Augmented sympathetic neurotransmitter activity in the peripheral vascular bed of patients with congestive heart failure and cardiac norepinephrine depletion. PMID- 4300396 TI - Laboratory cultivation of some human parasitic amoebae. PMID- 4300397 TI - Chemical and oxidative properties of coupled mitochondria from Aspergillus niger. PMID- 4300398 TI - The interaction of polyoma DNA with DNA polymerase. PMID- 4300399 TI - Mode of action of viomycin on Rhizobium meliloti. PMID- 4300400 TI - 19th Annual Meeting of the Histochemical Society, New Orleans, April 8-9, 1968. Symposium on critical evaluation of morphologic histochemical techniques for demonstrating enzymes. Evaluation of the specificity of enzyme histochemical reactions. PMID- 4300401 TI - Cytomegaloviruses in stored urine specimens. A quantitative study. PMID- 4300402 TI - Effect of ACTH on the electrical properties of adrenocortical cells. PMID- 4300404 TI - [Use of ACTH and hydrocortisone in treatment of acute diffuse peritonitis]. PMID- 4300403 TI - [On the specificity of the tumor cell-characteristic agglutinins of "wheat germ lipase"]. PMID- 4300405 TI - [Intralymphatic infusion of chemotherapeutic preparations]. PMID- 4300407 TI - [DNA splitting enzymes in rat hepatoma and liver extracts]. PMID- 4300406 TI - [On the prevention of postoperative recurrences in cancer of the ovaries]. PMID- 4300409 TI - [Metastasis of stomach cancer to the skin and tonsils (2 cases)]. PMID- 4300408 TI - [Correlation of the electrophoretic characteristics of blood serum proteins with the immunologic status of the organism in experimental hepatomas]. PMID- 4300410 TI - Ultrastructural basis of excitation and inhibition in mammalian autonomic ganglia. An electron cytochemical study. PMID- 4300411 TI - [So-called granuloma pyogenicum, with special emphasis on its pathogenesis]. PMID- 4300412 TI - [Effect of ectromelia virus on the development of the mouse fetus, with special reference to its effect on the development of the head region]. PMID- 4300413 TI - Granular cell myoblastoma of bronchus. PMID- 4300414 TI - [Serological detection of infectious rhinotracheitis in cattle in Slovakia]. PMID- 4300416 TI - [Studies on stomatitis palpulosa with reference to the differential diagnosis]. PMID- 4300415 TI - [Comparative fluorescence immunological and cytopathological studies with various virus strains of the mucosal disease of cattle]. PMID- 4300418 TI - Mucoepidermoid tumors of salivary glands in Western India. PMID- 4300417 TI - [On the histamine liberating effect of neomycin: the reactivity of neomycin with heparin]. PMID- 4300419 TI - [Chromatography of spleen phospodiesterase on sulphoethylcellulose and study of the enzyme's endonuclease activity]. PMID- 4300420 TI - [Isolation and purification of guanyl-ribonuclease from actinomycetes]. PMID- 4300421 TI - [The low-temperature luminescence spectra of adenine and its derivatives]. PMID- 4300422 TI - [Oxo- and amino acid photo-oxidation sensitized by chlorophyll]. PMID- 4300423 TI - [Intermediate steps of anaerobic cleavage of carbohydrates in human thrombocytes]. PMID- 4300424 TI - [On the biosynthesis of inorganic polyphosphates in Neurospora crassa]. PMID- 4300425 TI - [The properties of ribonuclease F]. PMID- 4300426 TI - [The study of the formation of lecithinase by Clostridium perfringens type A]. PMID- 4300427 TI - [The action of AMP, glucose-1-phosphate and glycogen on the enzymic and structural properties of native and acetylated phosphorylase a]. PMID- 4300428 TI - Bilateral ureteric metastases causing complete anuria. PMID- 4300429 TI - [Toxicological characteristics of some bis-chloromethyl derivatives of aromatic hydrocarbons]. PMID- 4300430 TI - [The lipid composition of microsomal fractions in the liver and hepatoma]. PMID- 4300431 TI - [Hematologic diversification of induced leukemias following the in-vitro cultivation of the mouse myeloid leukemia virus]. PMID- 4300432 TI - [Phosphofructokinase activity in normal and tumor tissues of rats]. PMID- 4300433 TI - [Studies on the heterogenicity of phosphatases in the porcine ovary]. PMID- 4300435 TI - Effects of collagenase on developing epithelia in vitro: lung, ureteric bud, and pancreas. PMID- 4300436 TI - Herpes simplex virus types 1 and 2 in various diseases. PMID- 4300434 TI - [On the histochemical demonstration of enzymes of the energy producing metabolism in dermatophytes of the genus Trichophyton]. PMID- 4300437 TI - Daunomycin in the treatment of acute leukaemia and neoplastic diseases in childhood. PMID- 4300438 TI - [On the differential diagnosis of benign and semimalignant tumors of the nasal septum]. PMID- 4300439 TI - [Suture of the extratemporal segment of the facial nerve]. PMID- 4300440 TI - Extended care closes gaps in continuity of care. PMID- 4300441 TI - Extramammary Paget's disease of the anus. PMID- 4300442 TI - Biochemistry laboratory experiment. Polarized fluorescence. PMID- 4300443 TI - [Radiological representation of retroperitoneal tumors at the level of duodenal structure]. PMID- 4300444 TI - A place for both the old and the new. PMID- 4300446 TI - [Content of a renin-like substance in normal and toxemic human placentas]. PMID- 4300445 TI - [Personal reflections on cancer of the prostate]. PMID- 4300448 TI - [On parotid gland surgery]. PMID- 4300447 TI - [Serum protein binding of ACTH. I. Studies using dextran gel filtration and H3 ACTH]. PMID- 4300449 TI - [Therapy of pseudomonas meningitis]. PMID- 4300451 TI - Culture characteristics of brain neuroglial cells from chickens infected with Rous sarcoma virus. PMID- 4300450 TI - Supraspinal control of transmission in the polysynaptic reflex pathway to montoneurones during sleep. PMID- 4300452 TI - [Nosology and diagnosis of myeloproliferative syndrome]. PMID- 4300453 TI - [Leukocytic alkaline phosphatase in acute leukemia and chronic myeloproliferative syndrome]. PMID- 4300455 TI - [Vaquez's diseas. Clinical and developmental study. Apropos of 144 cases]. PMID- 4300454 TI - [Primary and secondary thrombocythemia: apropos of 39 cases]. PMID- 4300456 TI - [Colloquy with the practitioner. The problem of artificial dermatitis]. PMID- 4300457 TI - [Results of surgical section and repair of the recurrent nerve]. PMID- 4300458 TI - Raeder's paratrigeminal syndrome. PMID- 4300459 TI - Oral poliovirus vaccination and breast feeding. PMID- 4300460 TI - [Studies on the corticotropic effectiveness of a synthetic, ACTH-like pentacosapeptide in man]. PMID- 4300461 TI - [Clinical experience with estriolsuccinate in corrective plastic surgery of the nose]. PMID- 4300462 TI - Granular cell myoblastoma. Report of three cases in the chest wall and review of the literature. PMID- 4300463 TI - [Relation between the blood-pressure effect of angiotensin II and the mean arterial pressure, serum sodium, serum potassium, serum angiotensinase and plasma renin in man]. PMID- 4300464 TI - [An uncommon dysontogenetic tumor of the bladder]. PMID- 4300465 TI - [The childhood hepatoma--review of literature and contribution to its etiology]. PMID- 4300466 TI - The conjugating mechanism in a case of etiocholanolone fever. PMID- 4300467 TI - [Total pancreatectomy for hypoglycemic langerhansian tumor (insuloma)]. PMID- 4300468 TI - [Various aspects of the ontogenesis of sleep in newborn infants. Its significance in the context of the fetal-maternal pair]. PMID- 4300469 TI - [Experience with the use of Visotrast in gastrointestinal diagnosis in children]. PMID- 4300470 TI - [Studies on the action duration of a new synthetic ACTH depot preparation]. PMID- 4300471 TI - [The use of the paramagnetic probing method for the study of the nucleic acid- water system]. PMID- 4300472 TI - [In vitro interaction between lymphoid cells and kidney cells of hamsters infected with polyoma virus]. PMID- 4300473 TI - Hypertrophic neuropathy: a report of Dejerine-Sottas disease in two sibs. PMID- 4300474 TI - Formation of giant polynuclear cells in cell lines by HVJ virus. PMID- 4300475 TI - Treatment of diabetic neuropathy with diphenylhydantoin. PMID- 4300476 TI - [Benign synovioma of the tendon shealth of the flexor of the little finger. Osseous radiographic and arteriographic aspects]. PMID- 4300477 TI - [Immunological conditions following natural infection with foot-and-mouth disease virus and after vaccination]. PMID- 4300478 TI - [Inactivation of foot-and-mouth disease virus with special consideration of tenacity and disinfection]. PMID- 4300479 TI - [Epizootiology of foot-and-mouth disease]. PMID- 4300480 TI - [Frequency distribution and forms of infantile cytomegaly in lower Austria]. PMID- 4300481 TI - [On carcinoma of the large intestine, with special reference to the juvenile age]. PMID- 4300483 TI - [Enzyme activities of the liver and epididymal adipose tissue in the rat in a state of nutritional obesity]. PMID- 4300482 TI - [Our experience in early diagnosis of cancer of the uterus and breast]. PMID- 4300484 TI - [The coenzyme A and the activity of coenzyme A synthetase in hepatoma in the white rat]. PMID- 4300485 TI - [Action of 3,5,3-triiodothyroacetic acid (TA3) on the state of oxidoreduction of the respiratory enzymes]. PMID- 4300486 TI - [On the diagnosis of enteroviruses. 3. Isolation of polioviruses]. PMID- 4300487 TI - [Cervical spinal cord angioma with recurrent attacks]. PMID- 4300488 TI - [Hepatitis epidemica and panmyelophthisis. Comments on the paper of B. Leinweber et al., published in Deutsch Med Wschr 92 (1967), 841]. PMID- 4300489 TI - Primary carcinoma of the liver. PMID- 4300490 TI - [On surgery of endocrine organs]. PMID- 4300491 TI - [The kidneys and vitamin D]. PMID- 4300493 TI - [Congenital granulocellular epulis]. PMID- 4300492 TI - [Carcinoma of the pancreas in childhood]. PMID- 4300494 TI - [On various aspects of African horse sickness in Morocco]. PMID- 4300495 TI - [Virus diseases of the respiratory tract in cattle]. PMID- 4300496 TI - [Myocardium infarct in horses with infectious anemia]. PMID- 4300497 TI - [On 2 cases of cystic pyeloureteritis studied with large doses of iodized contrast medium in a glucose solution]. PMID- 4300498 TI - Optic neuritis. PMID- 4300499 TI - [On the intravenous viomycin therapy]. PMID- 4300500 TI - [Transumbilical portal catheterization (a study of 120 umbilical portographies)]. PMID- 4300501 TI - [Study of the activity of some hydrolases (alkaline and acid phosphatases, acid proteinase and alanylglycine dipeptidase) of the oviduct of Rana esculenta during the reproductive cycle]. PMID- 4300502 TI - [High phosphatase content in the pineal body of swine]. PMID- 4300504 TI - [On malignant renal neoplasms in childhood]. PMID- 4300503 TI - [Carpal tunnel syndrome of the median nerve and compression syndrome of the ulnar nerve in the wrist joint]. PMID- 4300505 TI - A study of the possible basis of age-dependent resistance of mice to poxvirus diseases. PMID- 4300506 TI - The lactose synthetase particles of lactating bovine mammary gland. Preparation of particles with intact lactose synthetase. AB - 1. The particulate form of lactating bovine mammary lactose synthetase activity is shown to be more highly organized than previously reported. 2. A novel method of shattering frozen mammary tissue with effective cell disruption is described. 3. The apparent subcellular distribution of lactose synthetase was shown to reflect the method of homogenization. 4. After mild homogenization particles associated with a high content of intact lactose synthetase activity sedimented in the lysosome size range between 5x10(4) and 3x10(5)g-min. 5. Lactose synthetase was dissociated and solubilized by VirTis homogenization and ultrasonic treatment. The activities and behaviour of UDP-galactose hydrolase, succinate dehydrogenase, beta-glucuronidase and phosphodiesterase I were compared. 6. Inhibition of UDP-galactose hydrolase by UTP and alpha-lactalbumin was observed. PMID- 4300509 TI - The nature of soil humic acid. PMID- 4300507 TI - The lactose synthetase particles of lactating bovine mammary gland. Characteristics of the particles. AB - 1. The conditions that promoted the solubilization of particulate lactose synthetase were effective for solubilizing the thiamine pyrophosphatase of the Golgi apparatus but differed from those effective for beta-glucuronidase or acid phosphatase of lysosomes. 2. Lactose synthetase-containing particles did not bind Mg(2+) or Cs(+) ions, suggesting that they are not related to endoplasmic reticulum membranes. 3. Intact lactose synthetase and thiamine pyrophosphatase particles banded isopycnically at a density of 1.143 in a sucrose gradient. The dissociated ;A' sub-unit of lactose synthetase, UDP-galactose hydrolase, p nitrophenyl phosphate acid phosphatase, alkaline phosphatase and phosphodiesterase I were associated with particles of a broad density range from 1.12 to 1.20. Lysosomal enzymes beta-glucuronidase, arylsulphatase and beta glycerophosphate acid phosphatase were associated with particles of density 1.20, 1.175 and 1.15 respectively. 4. Rate-zonal sedimentation studies indicated that lactose synthetase particles have S(20,w) values exceeding 24000s, corresponding to spherical particles of diameter exceeding 5.4x10(-5)cm. 5. Electron micrographs of lactose synthetase particles purified over 20-fold revealed small spherical bodies (0.1-0.5mu) resembling lysosomes, the smaller of which were attached to membranes, and larger heterogeneous spherical or oval bodies (0.7 1.8mu) resembling lipofuscin secretory granules. 6. The relationship between lactose synthetase particles and the Golgi origin of secretion granules is discussed. PMID- 4300508 TI - Post-mortem glycolysis in ox skeletal muscle. Effect of pre-rigor freezing and thawing on the intermediary metabolism. AB - 1. Ox sternomandibularis muscle was ;slow-frozen' by placing it in air at -22 degrees or ;fast-frozen' by immersion in liquid air or acetone-solid carbon dioxide. In all cases muscles were frozen pre-rigor. Changes in length, pH and the concentrations of P(i), creatine phosphate, hexose monophosphate (glucose 1 phosphate+glucose 6-phosphate+fructose 6-phosphate), fructose diphosphate (fructose 1,6-diphosphate+(1/2) triose phosphate), lactate, ATP, ADP, AMP and NAD(+) during freezing and during subsequent thawing were determined. In addition some measurements were made of the changes in alpha-glycerophosphate, 3 phosphoglycerate, 2-phosphoglycerate, phosphoenolpyruvate and pyruvate concentrations during slow freezing. 2. Appreciable shortening and marked changes in chemical composition took place during slow freezing but not during fast freezing. 3. During slow freezing the hexose monophosphate concentration fell and fructose 1,6-diphosphate and triose phosphate increased substantially. Increases also took place in 3-phosphoglycerate, 2-phosphoglycerate and phosphoenolpyruvate, but not in pyruvate. 4. On thawing, most of the chemical changes were similar to those in unfrozen muscle post mortem, but took place much more rapidly; loss of NAD(+) was particularly rapid. Fast-frozen muscle metabolized at a faster rate on thawing than did slow-frozen muscle. 5. The overall changes in length during freezing and thawing were about the same in slow frozen as in fast-frozen muscle. PMID- 4300511 TI - The metabolism of 2-fluroic acid by Pseudomonas fluorescens F2. PMID- 4300510 TI - The chemistry of flavines and flavorproteins. Photoreduction of flavines by amino acids. AB - 1. Flavines are photoreduced through their triplet states by amines and amino acids (e.g. EDTA and dl-phenylglycine). The anaerobic photoreduction of FMN and several other flavines with dl-phenylglycine was analysed in terms of a detailed kinetic scheme. 2. The reaction produces equimolar amounts of benzaldehyde, carbon dioxide and reduced flavine. 3. The sensitivity of the rates to substituents in the dl-phenylglycine can be described by a Hammett rho-value of 1.1. 4. Phenylacetic acid behaves differently from dl-phenylglycine or benzylamine towards a series of flavines. 5. The photoreductions are quenched by several aromatic compounds. From the effects of light-intensity and temperature, and by comparison with potassium iodide quenching, it is concluded that inhibition by the aromatic compounds is not simply a collisional process. 6. FAD reacts more slowly than FMN both in the photoreduction and in dark reduction by NADH. Urea and dimethyl sulphoxide decrease the intramolecular interaction in FAD, but they have no effect on the rate of dark reduction of FAD compared with FMN. In contrast, the photoreduction of FAD is quicker in urea. PMID- 4300512 TI - Mineral translocation in germinating wheat grain. PMID- 4300513 TI - [Isolation of a bacterial parasite active on Gram-positive bacteria from samples of polluted water]. PMID- 4300515 TI - [Effect of quaternary ammonium compounds on the Newcastle disease virus and para influenza virus]. PMID- 4300514 TI - [On surgical treatment of hand deformities]. PMID- 4300516 TI - [Periodic ophthalmia as a symptom of virus diseases in the horse and cattle]. PMID- 4300517 TI - [The effect of low air temperature on the development of experimental silicosis]. PMID- 4300518 TI - [Diseases of the peripheral nervous system and degenerative disorders of the musculoskeletal system in miners (based on studies in the Kuzbass coal mines)]. PMID- 4300519 TI - [Ulcerative colitis (etiology, clinical picture and therapy)]. PMID- 4300520 TI - [Crohn's ileocolitis]. PMID- 4300521 TI - [Herpes in strange locations]. PMID- 4300522 TI - [Apropos of a post-phlebitic edema cured by psychosomatic methods]. PMID- 4300523 TI - [Comparative study of 100 cases of sero-negative (rheumatoid?) polyarthritis and 100 cases of sero-positive rheumatoid polyarthritis (R.P.)]. PMID- 4300524 TI - [On chronic stenosis of the small intestine]. PMID- 4300525 TI - [Psychopathologic aspects of male polygonosomy (Klinefelter's syndrome and XYY karyotype)]. PMID- 4300526 TI - [Osteomalacia]. PMID- 4300527 TI - [The effect of high doses of raubasine on the rehabilitation of patients with cerebrovascular disorders]. PMID- 4300528 TI - [The role of catecholamines in the clinical manifestations of the hyper- and hypothyroidism syndromes]. PMID- 4300529 TI - [Thyroid insufficiency without bradycardia]. PMID- 4300530 TI - [Paraneoplastic Cushing's syndrome. Total regression after removal of a malignant pulmonary tumor. 2-and-one half-year follow-up]. PMID- 4300532 TI - [Behavior of attenuated foot-and-mouth disease virus strains in the suckling mouse]. PMID- 4300531 TI - [Acute hemolytic anemia after the consumption of fava beans. Familial case study on glucose-6-phosphate dehydrogenase deficiency]. PMID- 4300533 TI - [Evaluation of adrenal cortex function in viral hepatitis]. PMID- 4300535 TI - Examination in vitro of the virus inhibitory action of a new benzthiazole derivative. PMID- 4300534 TI - Comparison of interferon production in vitro by leukocytes from healthy and polycythaemic persons. PMID- 4300536 TI - [Apropos of ovarian arrhenoblastoma]. PMID- 4300537 TI - [Theca cell tumor of the ovaries]. PMID- 4300538 TI - [Umbilical metastasis in ovarian carcinoma]. PMID- 4300539 TI - Histochemical study of the cerebral cortex in rats thyroidectomised at birth. PMID- 4300540 TI - Acetylcholine activation of carotid body chemoreceptor A fibers. PMID- 4300541 TI - [Hemagglutinin of Myxovirus influenzae. VI. Concentration of hemagglutinin with salts of simple anions]. PMID- 4300542 TI - The influence of adrenocortical hormones and vitamins upon tryptophan metabolism in man. PMID- 4300544 TI - The influence of oestradiol on the enzyme activities of regenerating vaginal epithelium in mice. PMID- 4300543 TI - [Friedreich's ataxia with peripheral nerve involvement resembling peroneal muscular atrophy]. PMID- 4300545 TI - The mechanism of pathogenicity of Pseudomonas aeruginosa. V. Isolation and properties of the proteinases toxic for larvae of the greater wax moth Galleria mellonella L. PMID- 4300546 TI - Enzymatic activity of basidiomycetes. II. Oxidation and dehydrogenation of NADH2 in Oudemansiella mucida. PMID- 4300548 TI - [Action specificity of neuraminidase. The action of bacterial neuraminidase on isomeric N,O-diacetylneuraminic acid glycosides in the submaxilllary mucin of horse and cow]. PMID- 4300547 TI - Biosynthesis and composition of phosphatides in outer and inner mitochondrial membranes. PMID- 4300549 TI - Reciprocal relations and proximity of bases in pyridine dinucleotides. PMID- 4300550 TI - Paramagnetic resonance study of Nitric Oxide hemoglobin. PMID- 4300551 TI - The enzymatic reduction of retinal to retinol in rat intestine. PMID- 4300552 TI - Metabolism of pyridinium precursors of pyridine nucleotides in perfused rat liver. PMID- 4300553 TI - Reactions of oxygenated cytochrome oxidase. PMID- 4300554 TI - Unidirectional inhibition of glutamate dehydrogenase by metabolites. A possible regulatory mechanism. PMID- 4300556 TI - The glycopeptide linkage of ribonuclease B. PMID- 4300555 TI - On the mechanism of action of adrenocorticotropic hormone. The inhibitory site of cycloheximide in the pathway of steroid biosynthesis. PMID- 4300557 TI - Cortisol binding affinity of plasma transcortin (CBA) as studied by competitive adsorption. PMID- 4300558 TI - Suppression of testosterone and androstenedione porduction rates with dexamethasone in women with idiopathic hirsutsm and polycystic ovaries. PMID- 4300560 TI - Effects of prednisone on vitamin D metabolism in man. PMID- 4300559 TI - A testicular-interstitial-cell-stimulating gonadotrophin in a child with hepatoblastoma and sexular precocity. PMID- 4300561 TI - Diurnal variation in the concentrations of solvolyzable steroids in human plasma. PMID- 4300562 TI - Plasma corticotrophin estimations in Addison's disease and following adrenalectomy for Cushing's disease. PMID- 4300563 TI - Lack of prolonged activity of a new ACTH preparation (DW-75) in human subjects. PMID- 4300564 TI - Biosynthesis of 18-hydroxydeoxycorticosterone from deoxycorticosterone-4-14C by the human adrenal gland. PMID- 4300565 TI - Effect of withdrawal of arginine and other amino acids on the synthesis of tumour and viral antigens of SV 40 virus. PMID- 4300566 TI - The complement-fixation test for avian leukosis. PMID- 4300567 TI - The neutralization of Rous sarcoma virus. PMID- 4300568 TI - Requirement of arginine for the replication of herpes virus. PMID- 4300569 TI - Tarsal tunnel syndrome. PMID- 4300570 TI - The hepatocarcinogenicity of some disubstituted 4-dimethylaminobenzenes. PMID- 4300571 TI - Studies in bullous diseases. Immunofluorescent serologic tests. PMID- 4300572 TI - Studies of liver glycogenoses, with particular reference to the metabolism of intravenously administered glycerol. PMID- 4300573 TI - Functional differentiation of glycogenoses of the liver with respect to the use of glycerol. PMID- 4300574 TI - Oxidation of NADH during contractions of circulated mammalian skeletal muscle. PMID- 4300576 TI - [Preparation of foot-and-mouth disease diagnostic serum with the use of rabbit tissue antigen]. PMID- 4300575 TI - [Minor tuberculostatic drugs]. PMID- 4300577 TI - [Identification of epizootic strains of the Ai variant of foot-and-mouth disease virus]. PMID- 4300578 TI - Infectious bovine rhinotracheitis: correlation of fetal and placental lesions with viral isolations. PMID- 4300579 TI - Infectious bovine rhinotrachetis: relationship of level of maternal antibody titer to incidence of fetal death and abortion. PMID- 4300580 TI - Electron microscopic studies on the development of vesicular stomatitis virus. PMID- 4300581 TI - The use of interferon production as a marker in the development of a modified strain of foot-and-mouth disease virus. PMID- 4300582 TI - Growth of Sendai virus in organ cultures of mouse tissue. PMID- 4300583 TI - [Characterization of various representatives of the Columbia-SK virus group with fluorescent antibodies. II. Adaptation of Columbia-SK viruses to L cells]. PMID- 4300584 TI - Some factors affecting interferon production by foot-and-mouth disease virus in bovine tissue cultues. PMID- 4300585 TI - Interference between modified and virulent strains of foot-and-mount disease virus. PMID- 4300586 TI - Morphologic characteristics and nucleic acid type of transmissible gastroenteritis virus of pigs. PMID- 4300587 TI - Comparative study of vesicular stomatitis virus and its plaque type mutant. PMID- 4300588 TI - A carrier state in hamster-embryo cells with the Naples strain of phlebotomus fever virus. PMID- 4300589 TI - Ionizing irradiation of foot-and-mouth disease virus and its ribonucleic acid. PMID- 4300590 TI - Electron spin resonane of iron-nitric oxide complexes with amino acids, peptides and proteins. PMID- 4300591 TI - Proteins of the human intervertebral disc. The association of collagen with a protein fraction having an unusual amino acid composition. PMID- 4300592 TI - One-electron reactions in biochemical systems as studied by pulse radiolysis. I. Nicotinamide-adenine dinucleotide and related compounds. PMID- 4300593 TI - Mechanism of oxidative phosphorylation in the chemoautotroph Nitrobacter agilis. PMID- 4300595 TI - Piericidin A and inhibition of respiratory chain activity in Escherichia coli K12. PMID- 4300594 TI - Cytochrome c552 and nitrite reduction in Escherichia coli. PMID- 4300596 TI - Inhibitor of spinach chloroplast fructose-1,6-diphosphatase by MgATP--,MgADP-and magnesium pyrophosphate (MgP207--). PMID- 4300597 TI - An effect of corticotropin on adrenal fatty acid synthesis. PMID- 4300598 TI - [REO virus infections in Costa Rica]. PMID- 4300599 TI - [The influence of modified dextrane preparations on the nonspecific resistance to infection]. PMID- 4300600 TI - [Reparative process in conditions of extirpation of the pituitary gland and of the hormonal effects]. PMID- 4300601 TI - The effect of piericidin A on energy-linked processes in submitochondrial particles. PMID- 4300602 TI - Differentiation of various types of cholinergic and other spasmogenic actions on the isolated guinea-pig ileum. PMID- 4300603 TI - Oxygen diffusion impairment as a sequel in a case of varicella pneumonia treated with adrenocortical steroids. PMID- 4300604 TI - Spontaneous nephroblastomas in laboratory rats. PMID- 4300605 TI - Neoplasia in nonhuman primates. PMID- 4300606 TI - Diagnosis and handling of B virus in a rhesus monkey (Macaca mulatta). PMID- 4300607 TI - Primary lung cancer. A twenty year experience. PMID- 4300609 TI - [Cystosarcoma phyllodes]. PMID- 4300608 TI - [Carinii pneumocystis and cytomegalic disease in an adult with Hodgkin's disease]. PMID- 4300610 TI - [Symptoms of tumors in the region of the optic chiasm and their practical significance]. PMID- 4300611 TI - [Effects of various phosphorus compounds on nitrogen fixation in azotobacter chroococcum]. PMID- 4300612 TI - Behavior in cattle of Iranian strains of foot-and-mouth disease virus subjected to serial passage in different kinds of cells. PMID- 4300613 TI - Behavior of foot-and-mouth disease virus on serial passage in different kinds of cells. A contribution to experimental epidemiology at cell level. PMID- 4300614 TI - Feline herpes virus: isolations and experimental studies. PMID- 4300616 TI - [An unusual localization of glioblastoma multivorme in the adult]. PMID- 4300615 TI - Clinical and endocrinological aspects of virilizing adrenocortical adenoma. PMID- 4300617 TI - Isolation of herpes-T virus from a spontaneous disease in squirrel monkeys (Saimiri sciureus). PMID- 4300618 TI - Distribution of virus neutralizing antibodies to different strains of rous sarcoma virus among "normal" chicks. PMID- 4300619 TI - The tween-ether treated hemagglutinin of parainfluenza 2 virus. PMID- 4300620 TI - Experimental infection with Sendai virus in mice. PMID- 4300621 TI - Direct electron-microscopy of organ culture for the detection and characterization of viruses. PMID- 4300622 TI - [The use of primary calf testis cell cultures for virology work]. PMID- 4300623 TI - Serum neutralization test with western equine encephalitis (WEE) and japanese encephalitis (JE) viruses using the agar cover slip (ACS) inoculation technique. PMID- 4300624 TI - The fate of murine hepatitis virus (MHV-3) after intravenous injection into susceptible mice. PMID- 4300625 TI - Changes in protein and nucleic acid metabolism in baby hamster kidney cells infected with foot-and-mouth disease virus. PMID- 4300626 TI - Some improved techniques for the study of rhinoviruses using HeLa cells. PMID- 4300628 TI - Temperature optima of mammalian and amphibian viruses in cell cultures of homeothermic and poikilothermic origin. PMID- 4300627 TI - Nature of febrile response to intravenous injection of large amounts of herpes simplex virus in guinea pigs. PMID- 4300629 TI - [Contribution to the density of plaque-variants of herpesvirus ho- minis in cesium chloride water gradient]. PMID- 4300630 TI - Selection of variants of rhinoviruses. PMID- 4300631 TI - [Cytochemical studies on the effects of boric acid and phenylboric acid on various oxidases and dehydrogenases in Oospora lactis (Fres.) Sacc. (cf. Geotrichum candidum Link.)]. PMID- 4300632 TI - [Enzyme histochemistry of the testis of domestic mammals. II. Hydrolases in the testis of the goat and pig]. PMID- 4300633 TI - Formation of the thymine radical in irradiated DNA. PMID- 4300634 TI - Techniques for DNA hybridization in vitro using non-radioactive DNA and DNA made radioactive by neutron activation, alkylation with radioactive alkylating agents, and by exchange with 3H2O. PMID- 4300635 TI - Alterations in vitro of amino acid incorporating activity of liver preparations of non-starved normal and stress-induced rats. PMID- 4300636 TI - Concerning the site of action of deoxyadenosine (deoxyadenosinetriphosphate) upon the synthesis of nucleic acids in the cancer cell. PMID- 4300637 TI - [The Motol virus. A study on the further properties of this virus]. PMID- 4300639 TI - [On the rehabilitation of nephrectomized patients]. PMID- 4300638 TI - [Hyperemesis gravidarum--causes and consequences of systemic disorders]. PMID- 4300640 TI - Induction of deoxycytidylate deaminase and uridine kinase and activation of cellular DNA synthesis in the course of transformation of chicken embryo cells infected by Rous sarcoma virus in vitro. PMID- 4300641 TI - [An electron microscopy study of the localization of synthetic, cytoprotective polymers against silica in the mouse liver (polyvinyl pridine-N-oxide and poly-p dimethylaminostryrene-N-oxide)]. PMID- 4300642 TI - [Qualitative and quantitative variations of nonesterified fatty acids in human plasms under the effect of intravenous perfusion of adrenocorticotropin hormone]. PMID- 4300643 TI - [Virological and clinical studies in congenital and postnatal cytomegalies]. PMID- 4300644 TI - [Neurophysiological studies of the mecahnism of action of thylethoxyphosphoryl paranitro-phenolate (armin) on the transmission of impulse on nuro-muscular synapses]. PMID- 4300645 TI - [Activity of hydrolases in the epithelium of the gallbladder of Rana temporaria L. under non-experimental conditions]. PMID- 4300646 TI - [Histometric and histochemical studies on the adrenal cortex of guinea pigs after treatment with aldosterone, DOCA, cortisone, and ACTH]. PMID- 4300647 TI - An electron microscopic study on the possible site of production of ACTH in the anterior pituitary of mice. PMID- 4300648 TI - Adrenal hyperaemia caused by corticotrophin. PMID- 4300649 TI - Adrenal responses to corticotrophin in the presence of an inhibitor of protein synthesis. PMID- 4300650 TI - In vitro corticosteroid biosynthesis in adrenals of rats uraemic after bilateral nephrectomy. PMID- 4300651 TI - Steroid hormone production following adrenal stimulation in the rhesus monkey. PMID- 4300652 TI - Plasma corticosteroid, plasma insulin and blood sugar of normal fasting and diabetic subjects with or without hypercorticism. PMID- 4300653 TI - The effect of exogenous corticotrophin on steroid excretion in the newborn. PMID- 4300654 TI - A clinical observation on the use of gonadotropins in the treatment of ulcerative colitis. PMID- 4300655 TI - Histochemical study of aminopeptidase in malignant neoplasms of the female genitals. PMID- 4300656 TI - Topical antibiotic spray in contaminated crush wounds in animals. PMID- 4300657 TI - Alterations in reticulo-endothelial functions as produced by the administration of bacterial toxins. PMID- 4300658 TI - Management of esophageal lesions caused by chemical burns. PMID- 4300660 TI - Drug withdrawal state. An EEG sleep study. PMID- 4300659 TI - Pancreaticoduodenectomy for Zollinger-Ellison syndrome. PMID- 4300661 TI - Quantitative haemadsorption. A fast and reliable screening test for anti myxoviral agents. PMID- 4300662 TI - Evidence for a single structural polypeptide in foot-and-mouth disease virus. PMID- 4300664 TI - [The use of intravenous carbocaine in grave neoplastic and neurological pain]. PMID- 4300663 TI - [Peculiarities of the reaction of the anterior portion of the pituitary gland of the guinea pig in disturbance of the sex hormone balance]. PMID- 4300665 TI - Tumours of the liver, kidney and lungs in rats fed Encephalartos hildebrandtii. PMID- 4300666 TI - Cell-free transmissible leukoses in Syrian hamsters, probably of viral aetiology. PMID- 4300667 TI - Microvascular effects of vasoactive agents in shock. PMID- 4300668 TI - Congenital cytomegalovirus infection treated with idoxuridine. PMID- 4300669 TI - Long-acting synthetic corticotrophin in dermatology. PMID- 4300670 TI - Effect of halothane and methoxyflurane anaesthesia on plasma cortisol concentration in relation to major surgery. PMID- 4300671 TI - [Tumors of the submaxillary and sublingual glands. Clinical contribution of 30 cases]. PMID- 4300672 TI - Oxidation of exogenous reduced nicotinamide adenine dinucleotide by liver mitochondria from essential fatty acid-deficient rats. PMID- 4300673 TI - Effect of protein intake on tissue amino acid levels and the enzymes of serine biosynthesis in the rat. PMID- 4300674 TI - Extended hemodialysis in children with chronic renal failure. PMID- 4300675 TI - The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. PMID- 4300677 TI - Actions of anticholinesterase agents upon ganglionic transmission in the dog. PMID- 4300676 TI - Impulse transmission via nicotinic and muscarinic pathways in the stellate ganglion of the dog. PMID- 4300678 TI - A study of the alteration in receptor activity of the rat fundal strip by urea. PMID- 4300679 TI - A simple, sensitive method for the assay of adenyl cyclase. PMID- 4300680 TI - Malignant transformation in vitro by oncogenic viruses. PMID- 4300681 TI - The second messenger. PMID- 4300682 TI - People who care. PMID- 4300683 TI - Human circadian rhythms and the 48 hour day. PMID- 4300684 TI - Physical exercise and alcohol metabolism in man. PMID- 4300685 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 45-1968. PMID- 4300686 TI - [Traumatic paralysis of the sciatic in peace time. Considerations on 40 operated cases]. PMID- 4300687 TI - Genital infection with Herpesvirus hominis types 1 and 2 in children. PMID- 4300688 TI - Glycogen storage in a hepatoma: dephosphophosphorylase kinase defect. PMID- 4300689 TI - Persistent angiographic abnormalities after cure of malignant trophoblastic disease. PMID- 4300690 TI - Radiation therapy of brachial plexus syndrome from breast cancer. PMID- 4300691 TI - Treatment of Clostridium welchii infection with hyperbaric oxygen. PMID- 4300692 TI - The epithelium in wound healing. PMID- 4300693 TI - Biosynthesis of trans-geranylgeranyl pyrophosphate in endosperm of Echinocystis macrocarpa Greene. PMID- 4300694 TI - Conversion of 14C-labeled geranylgeranyl pyrophosphate to phytoene by a soluble tomato plastid enzyme system. PMID- 4300695 TI - Effect of menadione on the electron transport pathway of yeast mitochondria. PMID- 4300696 TI - Studies on the synthesis of fatty acids by a beef heart mitochondrial enzyme system. PMID- 4300697 TI - A phosphatidylinositol kinase in rat kidney cortex. PMID- 4300698 TI - The isolation of infectious bovine rhinotracheitis virus from bovine semen. PMID- 4300699 TI - 25-hydroxycholecalciferol. A biologically active metabolite of vitamin D3. PMID- 4300700 TI - A dimer of diphosphopyridine nucleotide. PMID- 4300701 TI - 5-carboxymethyluridine, a novel nucleoside derived from yeast and wheat embryo transfer ribonucleates. PMID- 4300703 TI - Feedback inhibition of glutamine synthetase of Neurospora crassa by nicotinamide adenine dinucleotide. PMID- 4300702 TI - Fractionation of transfer ribonucleic acid on a methylated albumin-silicic acid column. I. Preparation of the column. PMID- 4300704 TI - Fructose diphosphatase from rabbit liver. X. Isolation and kinetic properties of the enzyme--adenosine monophosphate complex. PMID- 4300705 TI - Purification, properties, and allosteric activation of nucleoside diphosphatase. PMID- 4300706 TI - The phosphofructokinase of Dictyostelium discoideum. PMID- 4300707 TI - Parathyroid hormone and renal cell metabolism. PMID- 4300708 TI - Amino acid transfer factors from yeast. II. Interaction of three partially purified protein fractions with guanosine triphosphate. PMID- 4300710 TI - Histoenzymatic activities of three KB cell lines latently infected by Myxovirus parainfluenzae, type 3, strain EA-102. I. Aminopeptidase activity. PMID- 4300709 TI - The cyclic phosphodiesterases (3'-nucleotidases) of the enterobacteriaceae. PMID- 4300711 TI - Histoenzymatic activities of three KB cell lines latently infected by Myxovirus parainfluenzae, type 3, strain EA-102. II. Hydrolytic and oxidative enzyme activity. PMID- 4300712 TI - Variation in susceptibility of chick embryo tissues to infection with Rous sarcoma virus in vitro. PMID- 4300713 TI - Action of pyridine-2-aldoxime methochloride (PAM) on neuromuscular transmission in vitro and in vivo. PMID- 4300714 TI - Cylindroma (remote) and giant follicular lymphoblastoma with paraplegia following radiation therapy in a 62-year-old woman. PMID- 4300715 TI - Encephalo-myelo-radiculo-neuropathy. PMID- 4300716 TI - Hepatocarcinogenicity of the herbicide maleic hydrazide following parenteral administration to infant Swiss mice. PMID- 4300717 TI - Growth of the XV40-adeno 7 hybrid virus in human diploid cells. PMID- 4300719 TI - The tarsal tunnel syndrome. PMID- 4300718 TI - Virus particles in bone marrow megakaryocytes and susceptibility of mice to virus induced leukemia. PMID- 4300720 TI - Potentiation of the biologic activity of ACTH by human plasma. A preliminary study. PMID- 4300721 TI - Effect of adrenocorticotropin and glucocorticoids on insulin secretion. PMID- 4300722 TI - Toxicity of combines histamine and serotonin in normal, pertussis -sensitized, and beta-adrenergically blocked mice. PMID- 4300723 TI - Malignant tumors of childhood masquerading as acute surgical conditions. PMID- 4300724 TI - Approach to tumors of the nose, nasopharynx and paranasal sinuses. PMID- 4300725 TI - Polybactrin soluble in neurosurgical practice. PMID- 4300726 TI - A comparison between the inhibitory effect of perchlorate on iodide and pertechnetate concentrations in saliva in man. PMID- 4300727 TI - Egg transmission studies of type II leukosis infection (Marek's disease). PMID- 4300728 TI - The effect of hypophysectomy on the lipid pattern of the adrenal cortex in mice with spontaneous adrenocortical lipid depletion. A histological study. PMID- 4300729 TI - Comparative histological and sputumcytological studies of the bronchial epithelium in inflammatory and neoplastic lung disease. PMID- 4300730 TI - Growth in rat of a sarcoma derived from rat kidney cells transformed in vitro by SV40. PMID- 4300732 TI - Types of contacts in vitro between rous mouse tumour cells and chicken fibroblasts as studied with the electron microscope. PMID- 4300731 TI - The effect of an oral contraceptive as a preparatory mechanism in the generalized Shwartzman reaction in rabbits. PMID- 4300733 TI - Investigations on the enzymes and toxins of staphylococci. Separation of lipase from phosphatase and spectophotometric analysis of the "egg yolk reaction". PMID- 4300734 TI - [Aspects of the electronic structure of phenothiazines]. PMID- 4300735 TI - EPR studies of psychotropic drug interactions at cell membranes. PMID- 4300736 TI - The action of phenothiazines and some pyridazone derivatives on respiratory enzymes in vivo and in vitro. PMID- 4300738 TI - [The nucleic acid aynthesis in pig kidney cells after infection with the virus of foot-and-mouth disease]. PMID- 4300737 TI - [Extracellular dehydration]. PMID- 4300739 TI - [Different sensitivity of various cell culture systems to ribonucleic acid from, for cell cultures noninfectious, foot-and-mouth disease virus]. PMID- 4300740 TI - Homotypic and heterotypic antibody response in infants to adenovirus vaccine. PMID- 4300741 TI - Studies on the pathogenesis of African swine fever. I. Quantitative studies on the sequential development of virus in pig tissues. PMID- 4300742 TI - Quantitative studies on the quality, effects of aggregation and thermal inactivation of vesicular stomatitis virus. PMID- 4300743 TI - Inhibitory effects evoked through ventral reticulospinal pathways. PMID- 4300744 TI - [Effect of imipramine and desipramine on noradrenaline-liberation in sympathetic neurons under calcium-efficiency conditions]. PMID- 4300745 TI - [Presence of a phosphatase in the in vitro RNA synthesis system of the R17 phage]. PMID- 4300746 TI - [Study of the mechanism of the induction of the development of SV 40 virus in transformed Syrian hamster cells: kinetics of the appearance of infectious DNA]. PMID- 4300747 TI - [Augmentation of the synthesis of serotonin in rats selectively deprived of paradoxical sleep]. PMID- 4300748 TI - [Occurrence of primary bilateral breast carcinomas]. PMID- 4300749 TI - [The clinical picture and therapy of rabies]. PMID- 4300750 TI - [Inhibition of insulin secretion by alpha adrenergic stimulatory agents]. PMID- 4300751 TI - [Gravimetric methods for determination of Parkopan, Spasman and Dispasmol. 2. On the analysis of some spasmolytics]. PMID- 4300752 TI - [Addison's disease cured after antitubercular antibiotherapy. Hormone study and discussion]. PMID- 4300753 TI - [Studies on a biologic radiation protection. 87. On the effect of sulfur containing organic substances on x-ray induced radicals in freeze dried rat liver]. PMID- 4300755 TI - [Effect of serotonin on some pathways of oxidative metabolism in the mitochondria of rabbit heart muscle]. PMID- 4300754 TI - [On two types of catalase in liver and transplantable hepatoma]. PMID- 4300756 TI - [Improved method for the preparation of carnosine from meat, and quantitative determination of carnosine by paper chrmatography]. PMID- 4300757 TI - [What does massive-dose estrogen therapy accomplish in the monophasic cycle and in oligomerrhea?]. PMID- 4300759 TI - Respiratory virus infections other than influenza. PMID- 4300758 TI - [Gas gangrene in uterine infections and its treatment]. PMID- 4300760 TI - Serologic surveys of Arctic populations and some virus diseases of interest. PMID- 4300761 TI - Pathophysiological aspects of human adjustment to cold. PMID- 4300762 TI - The triplet state of pyridoxal. PMID- 4300763 TI - Some properties of the polynucleotide phosphorylase and ribonuclease II of Escherichia coli 1113B. PMID- 4300764 TI - Site of action of adrenocorticotropic hormone (ACTH) in adrenal cell cultures. PMID- 4300765 TI - Induction of cellular DNA synthesis in chick embryo fibroblasts infected with Rous sarcoma virus in culture. PMID- 4300766 TI - NADH oxidase in blue-green algae. PMID- 4300768 TI - Herpesvirus hominis infections. PMID- 4300767 TI - Acute necrotizing lepromatous lymphadenitis: an erythema-nodosum-leprosum-like reaction in lymph nodes. AB - Histological examination of lymph-node biopsy specimens in 12 patients with erythema nodosum leprosum showed almost complete replacement of the node by lepromatous granuloma, together with considerable polymorph infiltration. Ziehl Neelsen staining demonstrated numerous Mycobacterium leprae present in the nodes. The majority of these patients were very ill, and responded to prednisolone or corticotrophin.It is suggested that the histological appearances may represent an intensive inflammatory response in the lymph nodes followed by avascular aseptic necrosis. PMID- 4300769 TI - [Pharmacology of isolated veins]. PMID- 4300770 TI - Antibiotics--1968. Review. PMID- 4300771 TI - Bilateral Wilms' tumor. Diagnosis and management. PMID- 4300772 TI - The Synacthen test of adrenal cortical function in children. PMID- 4300773 TI - [Infantile pneumonia in adenovirus infection]. PMID- 4300774 TI - Pathogenesis of Rous sarcoma virus in the chick embryo with particular reference to vascular lesions. PMID- 4300775 TI - [Modifications of carbohydrate metabolism observed during hepatocarcinogenesis induced by DAB. I. Studies on glycogen metabolism]. PMID- 4300776 TI - Altered properties of Fujinami-virus-infected duck cells and murine sarcoma virus infected rat cells. PMID- 4300777 TI - The molecular and electronic structure of vitamin B12r, cobaloximes(II), and related compounds. PMID- 4300778 TI - [Mucoid pseudocysts of the peripheral nerves]. PMID- 4300779 TI - The intraspinal distribution of some depressant amino acids. PMID- 4300780 TI - Lipid composition of glial cells isolated from bovine white matter. PMID- 4300781 TI - Relation of dreaming and REM sleep: the effects of REM deprivation under two conditions. PMID- 4300782 TI - Experience in a growth and development clinic with particular reference to growth hormone deficiency. PMID- 4300783 TI - Paget's disease of the nipple. PMID- 4300784 TI - Pancreatic islet cell tumour demonstrated by aortography. PMID- 4300786 TI - Sleep and dream patterns in twins. Markov analysis of a genetic trait. PMID- 4300785 TI - Virus infections. PMID- 4300787 TI - Control of epinephrine synthesis by the pituitary and adrenal cortex: possible role in the pathophysiology of chronic stress. PMID- 4300788 TI - [Recent data on the phenomena of lipolysis in adipose tissue]. PMID- 4300789 TI - [Hormonal regulation of enzymes correlated with steroidogenesis of the adrenal gland]. PMID- 4300790 TI - Electron paramagnetic resonance signal produced by ferricyanide in photosynthetic plant materials. PMID- 4300791 TI - [Proposal of prophylactic measures against abortion in mares due to rhinopneumonia virus]. PMID- 4300792 TI - Encephalopathy and fatty degeneration of the viscera in childhood: II. Report of a case with isolation of influenza B virus. PMID- 4300793 TI - [The lipolytic action of ACTH. II. Studies of obese children]. PMID- 4300794 TI - [On hypophosphatasia]. PMID- 4300795 TI - In vitro uptake of ascorbic acid-1-14-C by adrenal glands of different species of animals. PMID- 4300796 TI - Porcine enterovirus antisera prepared in chickens. PMID- 4300797 TI - Reaction of young adult sheep to vaccination and infection with myxovirus parainfluenza 3. PMID- 4300798 TI - An improved method for the isolation and identification of bluetongue virus by intravenous inoculation of embryonating chicken eggs. PMID- 4300799 TI - [On the problem of the etiology of spontaneous leukemia in mice of strain C57]. PMID- 4300800 TI - The displacement of stages 4 and REM sleep with a full night of sleep. PMID- 4300801 TI - [On vasorenal hypertension, radiographic and physiologic aspects]. PMID- 4300802 TI - The unusual in urology. PMID- 4300803 TI - [The occurrence of intestinal parasites in school children in the Tygerberg area]. PMID- 4300804 TI - Insect salivary glands: stimulation of fluid secretion by 5-hydroxytryptamine and adenosine-3',5'-monophosphate. AB - Low concentrations (10(-9)M) of 5-hydroxytryptamine increase the rate of fluid secretion by isolated salivary glands of adult Calliphora. 5-Hydroxytry ptamine is present in Calliphora brain. Adenosine-3',5'-monophosphate (cyclic AMP) also stimulates fluid secretion and may be involved in the mode of action of 5 hydroxytryptamine. PMID- 4300805 TI - [Some peculiarities in the accumulation of thiamine and its phosphates in the erythrocytes of rats]. PMID- 4300806 TI - [A study of the activity of blood enzymes in healthy infants during the 1st year of life]. PMID- 4300807 TI - [On the histogenesis of adenomatosis of the lungs in man]. PMID- 4300808 TI - Peripheral inhibition n crustacean muscle. PMID- 4300809 TI - Electron spin resonance investigations on ferricytochrome c compounds. PMID- 4300810 TI - The influence of Bordetella pertussis on the kinetics of antibody production to sheep red blood cells in NMRI mice. PMID- 4300811 TI - On the mannophosphoinositides of Mycobacterium 607. PMID- 4300812 TI - Separation by gas-liquid chromatography of the glycerol and erythritol glycosides of D-glucopyranose and maltose. Periodate and methylation studies on a synthetic "polymaltose". PMID- 4300814 TI - Analysis of antibiotics by gas chromatography. I. Lincomycin. PMID- 4300813 TI - Separation, identification and estimation of Cr3 complex ions. Thin-layer chromatography and diffuse reflectance spectroscopy. PMID- 4300815 TI - [The effect of angiotensin II on general and renal hemodynamics]. PMID- 4300816 TI - [On glomus tumor of the finger phalanges]. PMID- 4300817 TI - [Treatment of Cushing's syndrome]. PMID- 4300818 TI - [Some observations on the determination of urinary 17-ketosteroids in various climacteric conditions]. PMID- 4300819 TI - [Observations on the plasmatic angiotensinase activity in the course of pregnancy and the puerperium in subjects with gestosic syndrome]. PMID- 4300820 TI - [Primary tumors and cysts of the liver in children]. PMID- 4300821 TI - [The use of polymyxin in surgical practice]. PMID- 4300822 TI - [The effect of various gamma aminobutyric acid doses on the total and individual phospholipid levels in whole blood entering and leaving the brain]. PMID- 4300824 TI - Subclinical cytomegalovirus infections and cytomegalovirus mononculeosis after open heart surgery. PMID- 4300823 TI - [Glycolytic oxidoreduction connected with phospgorylation in extracts from muscles of control rabbits and vitamin E deficient animals]. PMID- 4300825 TI - Aftercare of the psychiatric patient: an 1847 view. PMID- 4300826 TI - Lung cancer following atomic radiation. PMID- 4300827 TI - Ethambutol in re-treatment of pulmonary tuberculosis. PMID- 4300828 TI - Kinetic and spectrophotometric studies on the renaturation of deoxyribonucleic acid. AB - The kinetics of the renaturation of Escherichia coli DNA in 0.4-1.0m-sodium chloride at temperatures from 60 degrees to 90 degrees have been studied. The extent of renaturation was a maximum at 65 degrees to 75 degrees and increased with ionic strength, and the rate constant increased with both ionic strength and temperature. The energy and entropy of activation of renaturation were calculated to be 6-7kcal.mole(-1) and -40cal.deg.(-1)mole(-1) respectively. It has been shown that renaturation is a second-order process for 5hr. under most conditions. The results are consistent with a reaction in which the rate-controlling step is the diffusion together of two separated complementary DNA strands and the formation of a nucleus of base pairs between them. The kinetics of the renaturation of T7-phage DNA and Bordetella pertussis DNA have also been studied, and their rates of renaturation related quantitatively to the relative heterogeneity of the DNA samples. By analysis of the spectra of DNA at different stages during renaturation it was shown that initially the renatured DNA was rich in guanine-cytosine base pairs and non-random in base sequence, but that, as equilibrium was approached, the renatured DNA gradually resembled native DNA more closely. The rate constant for the renaturation of guanine-cytosine base pairs was slightly higher than for adenine-thymine base pairs. PMID- 4300829 TI - Aspects of the chemistry of D-glyceraldehyde 3-phosphate dehydrogenase. AB - Crystalline d-glyceraldehyde 3-phosphate dehydrogenase from lobster tail contains 4 moles of NAD(+) bound and reacts specifically with 4 moles of iodoacetic acid/mole of tetramer. The essential thiol group of d-glyceraldehyde 3-phosphate dehydrogenase appears to react with iodoacetic acid with a rate constant for the overall process that is independent of the extent of carboxymethylation. The d glyceraldehyde 3-phosphate dehydrogenase-NAD(+) absorption band has a variable molar extinction coefficient in the presence of phosphate that may be correlated with a proton dissociation of pK 6.86. The binding of NAD(+) to d-glyceraldehyde 3-phosphate dehydrogenase weakens as alkylating agents react with the enzyme, and NAD(+) promotes the reactivity of the essential thiol group. It is suggested that, on binding to d-glyceraldehyde 3-phosphate dehydrogenase, NAD(+) lowers the pK of the essential thiol group, resulting in a catalytic role of NAD(+) in the reaction catalysed by d-glyceraldehyde 3-phosphate dehydrogenase. If this theory is correct, then it is likely that a proton will be liberated during the phosphorolysis of the acyl-enzyme rather than in the redox step. PMID- 4300831 TI - Electron paramagnetic resonance observations on biogenic semiquinone and 5-methyl phenazinium radicals. PMID- 4300830 TI - Diversity and nature of ribosomal pools in hepatoma 7800 and host liver. AB - 1. The ribosomal components in the postmitochondrial supernatant of a rat hepatoma (hepatoma 7800) and the corresponding host liver were examined for diversity and functional competence. 2. The ;free' and ;membrane-bound' polyribosomes of both tissues were equally active in vivo and had equilibrated with newly synthesized ribosomes 4hr. after administration of [6-(14)C]orotic acid. 3. The inactive monomer-dimer pool in hepatoma 7800 was unattached to membranes and a larger fraction of the polyribosomes was free in hepatoma than in liver. 4. By using sensitivity to puromycin as a criterion, evidence was obtained that most of the polyribosomes in hepatoma 7800 were active in vivo. 5. Actinomycin, azaguanine and carbon tetrachloride caused marked conversion of polyribosomes into inactive monomers and dimers in the host liver and moderate conversion in the hepatoma. 6. Significant accumulation of ferritin and shifts in the mean polyribosome size to the lighter species occurred in the host liver of rats bearing large hepatomas. PMID- 4300832 TI - A histochemical study of the reticuloendothelial system of human marrow--its possible transport role. PMID- 4300833 TI - Tetanus toxin and spinal inhibition. PMID- 4300834 TI - Effects of ACTH, dexamethasone and asphyxia on electrical activity of the rat hypothalamus. PMID- 4300835 TI - Presynaptic inhibition of cuneate transmission by widespread cutaneous inputs. PMID- 4300836 TI - Management of schizfphrenia in the community. PMID- 4300837 TI - Biochemical and quantitative electron microscopic evidence for heterogeneity of mitochondria from Saccharomyces cerevisiae. PMID- 4300838 TI - High resolution autoradiographic studies of the uptake of 3H-5-uridine into condensed and dispersed chromatin of nuclei and granular and fibrillar components of nucleoli of Novikoff hepatoma ascites cells. PMID- 4300840 TI - The inhibition of mevalonic kinase by geranyl and farnesyl pyrophosphates. PMID- 4300839 TI - Nutritional requirements of mouse adrenal cortex tumor cells in culture. PMID- 4300841 TI - The complete and centralised treatment of paraplegia. PMID- 4300842 TI - [Mechanism of secretion of renin]. PMID- 4300843 TI - [Action of angiotensin on the sympathetic nervous system]. PMID- 4300844 TI - [Production and excretion of corticosteroids in primary hyperaldosteronism]. PMID- 4300845 TI - [Can angiotensin have a vasodilating action?]. PMID- 4300846 TI - [The effect produced on the rat nephron by microinjections of angiotensin II in the peritubular capillaries]. PMID- 4300847 TI - [The influence of water uptake on natriuresis due to angiotensin in rats]. PMID- 4300848 TI - [Circulatory removal of angiotensin: a problem of vascular and molecular specificity]. PMID- 4300849 TI - [Secondary aldosteronism]. PMID- 4300850 TI - [A study of the pressor effect of angiotensin (Kaplan's test) and of renin activity in chronic renal failure treated by repeated extra-renal dialysis. The effect of diuretics, fluid loss and potassium depletion]. PMID- 4300851 TI - [The reinin- angiotensin-aldosterone system in essential and renovascular hypertension]. PMID- 4300852 TI - [The renin-angiotensin system during normal and pathologic pregnancy]. PMID- 4300853 TI - [Radiotherapy of Wilm's tumor]. PMID- 4300854 TI - [Pleomorphic adenoma (mixed tumor) of the lip]. PMID- 4300856 TI - Simultaneous bilateral nephrectomy and renal allotransplantation for bilateral Wilms' tumor. PMID- 4300857 TI - Use of bone age in the diagnosis of short children. PMID- 4300855 TI - Studies of sterility of calf venous blood. PMID- 4300859 TI - [Further study of the problem of tumor specificity of N-acetyl-D-galactosamine in 2 ascites tumors]. PMID- 4300860 TI - Somnolence in rhesus monkey following intracerebral inoculation. PMID- 4300858 TI - Hepatoma and groundnuts in the West Nile district of Uganda. PMID- 4300861 TI - [On the vasopressor effect and inactivation of angiotensin in essential and renal as well as experimental hypertension]. PMID- 4300862 TI - [On several cases of Capdepont's disease]. PMID- 4300863 TI - [Structure-analytical observations of endocrine correlations]. PMID- 4300864 TI - [Studies on the antibacterial effect of newer antibiotics on Welch-Fraenkel gas gangrene bacilli (Cl. perfringens)]. PMID- 4300865 TI - [Degradation of polypeptide-metal complexes. VI. Degradation of the Ni2+ angiotensin complex by H2O2]. PMID- 4300866 TI - Tartaric acid metabolism. 8. Crystalline tartronic semialdehyde reductase. PMID- 4300867 TI - Alterations in lactate dehydrogenase of the brain, heart, skeletal muscle, and liver of rats of various ages. PMID- 4300868 TI - Enzymatic desaturation of stearyl acyl carrier protein. PMID- 4300869 TI - Hypopituitarism associated with cavernous sinus thrombosis. Report of a case. PMID- 4300870 TI - The release of adenosine triphosphate from frog skeletal muscle in vitro. AB - 1. Active frog sartorius muscle in vitro liberates a substance into the bathing solution which has a pronounced stimulatory action on the frog heart.2. The stimulatory effect is not due to an increase in the K(+) concentration of the bathing solution, nor is it due to the liberation of catecholamines.3. In a molecular sieve chromatography procedure the stimulatory substance can be eluted in a single fraction which shows a maximum absorption of U.V. light at a wave length of 265 nm, indicative of the presence of substances containing a purine ring.4. Low concentrations (10(-7)-10(-8) g/ml.) of adenosine triphosphate (ATP), adenosine diphosphate (ADP) and uridine triphosphate (UTP) have a marked stimulatory action on the frog heart. The action of ATP and ADP on the heart is qualitatively very similar to that of the muscle bathing solution, while the action of UTP is distinctly different. The triphosphates of inosine, cytidine and guanosine stimulate the heart when in high concentration only. Adenosine and adenosine monophosphate do not stimulate the heart.5. Incubation of the muscle bathing solution and of solutions of ATP with the enzyme apyrase for the same time produces a similar marked reduction in the stimulatory action of both on the heart. Apyrase catalyses the break-down of nucleotide triphosphates to monophosphates.6. The elution behaviour of the stimulatory substance determined by molecular sieve chromatography is the same as that for ATP.7. The muscle bathing solution causes light to be emitted from firefly lantern extract, the pattern of light emission being similar to that produced by nucleotide triphosphates.8. The concentrations of ATP having the same quantitative action on the frog heart and on firefly extract as a given muscle bathing solution are almost identical, whereas the matching concentrations of ADP and UTP in the two methods of assay are widely different.9. It is concluded that ATP is released from active frog skeletal muscle in vitro. This release may play an important part in the reactive hyperaemia of muscular exercise since ATP has a powerful vasodilator action. PMID- 4300873 TI - [Glomus tumor with primary intra-osseous development. Case report]. PMID- 4300872 TI - [The behavior of the gestosic placenta in the regulation of glucide metabolism]. PMID- 4300874 TI - [Umbilical fibriangioma simulating an umbilical hernia]. PMID- 4300871 TI - A study of the mechanism of quantal transmitter release at a chemical synapse. AB - 1. The nerve-muscle preparation of the cutaneous pectoris of the frog has been used to study quantal transmitter release.2. When the osmotic pressure of the external solution is raised 1.5-2 fold, the frequency of miniature end-plate potentials (m.e.p.p.s) rises by 1.5-2 orders of magnitude. This effect is independent of the presence of Ca(2+) ions and of the nature of the substances by which the osmotic pressure has been increased.3. In Ca(2+) free hypertonic solution the nerve impulse still invades the nerve terminals but does not alter the frequency of the m.e.p.p.s.4. The arrival of the impulse in the terminals causes an immediate increase in the rate of quantal release, provided divalent cations are present whose passage through the axon membrane is facilitated by excitation (Ca(2+), Sr(2+), Ba(2+)).5. Divalent cations which penetrate only slightly (Mg(2+), Be(2+)) lower the frequency of m.e.p.p.s and suppress the end plate potential (e.p.p.) evoked by an impulse, in the presence of Ca(2+) ions. Be(2+) is a more effective inhibitor than Mg(2+).6. In Ca(2+) free solutions, adding Mg(2+) causes an increase in the frequency of m.e.p.p.s evoked by depolarization of the nerve endings or by treatment with ethanol.7. The trivalent cation La(3+) is more effective than divalent cations are in increasing the frequency of m.e.p.p.s. The tetravalent cation Th(4+) also raises the m.e.p.p. frequency.8. The observations summarized in paragraphs 2-7 indicate that the frequency of m.e.p.p.s at a constant temperature depends only on the concentration of uni-, di- and trivalent cations inside the nerve ending. It is suggested that the internal cation concentration influences the adhesion between synaptic vesicles and the membrane of the nerve ending.9. For a model experiment, artificial phospholipid membranes have been used to study the effect of uni-, di , tri- and tetravalent cations on the adhesion process. At pH 7-7.4, the time required for adhesion to take place decreases with increasing cation concentration in the bath. Ca(2+) ions are 100-1000 times more effective than K(+) ions; La(3+) and Th(4+) ions are still more effective. The ;adhesion time' decreases when the pH is lowered; it increases greatly with lowering of temperature.10. The hypothesis is put forward that the mutual adhesion of artificial vesicles made of phospholipid membranes, and the adhesion between synaptic vesicles and the membrane of the nerve ending arise by a common mechanism. In both cases, the important factor is the influence of cations on the electric double layer at the membrane surface. PMID- 4300875 TI - [Statistical data on cases of tumors observed at the Clinica Pediatrica dell'Universita di Napoli from 1952 to 1964]. PMID- 4300876 TI - [Myoid tumors of the stomach]. PMID- 4300877 TI - Studies on the formation of hyperplastic focus by variola virus in human cell cultures. II. Virus growth and focus formation in HeLa cell cultures. PMID- 4300878 TI - Herpes simplex virus DNA. PMID- 4300880 TI - SV40 T antigen induction and transformation in human fibroblast cell strains. PMID- 4300879 TI - Distribution and translation of poliovirus RNA in guanidine-treated cells. PMID- 4300882 TI - The lipids of paramyxoviruses: a comparative study of Sendai and Newcastle disease viruses. PMID- 4300881 TI - Cellular interactions of several enteroviruses and a reovirus after treatment with sodium borohydride or carbohydrases. PMID- 4300883 TI - Some remarks on the morphology of virus particles of the B type and their isolation from mammary tumors. PMID- 4300884 TI - In vitro cultivation of the mouse mammary tumor virus: replication of MTV in tissue culture. PMID- 4300885 TI - Use of mixed hemagglutination technique in detection of virus-induced antigen(s) on SV40-transformed cell surface. PMID- 4300886 TI - Ultraviolet inactivation of MM virus RNA in terms of sodium chloride concentrations. PMID- 4300887 TI - [Animal experimental studies of the pathogenesis of cardiopulmonary complications after lymphography]. PMID- 4300888 TI - Sulphatase activity in human epidermis and various tumours. PMID- 4300889 TI - Two rare forms of tumour in the hypothalamo-hypophysial system. Infundibular choristoma and glioblastoma infiltrating the pituitary. PMID- 4300891 TI - Structural and functional changes in rat kidney during CCl4 intoxication. PMID- 4300890 TI - Studies on cellular autophagocytosis. The formation of autophagic vacuoles in the liver after glucagon administration. PMID- 4300892 TI - Granular cell myoblastoma of the breast. PMID- 4300893 TI - Synovial sarcoma of the anterior abdominal wall. PMID- 4300894 TI - Plaque formation by 55 rhinovirus serotypes. AB - Plaque production by 55 rhinoviruses in several lines of HeLa cells is reported. Forty-nine types produced macroscopic plaques under the conditions described previously employing 30 mM MgCl(2) and 30 mug/ml of DEAE-dextran in overlay and M HeLa cells. Basically three kinds of plaques were observed: clear large and intermediate sized plaques and small turbid plaques. Five rhinoviruses produced plaques only in a sensitive clonal line isolated from the M HeLa line. Rhinovirus type 4 produced plaques after the pretreatment of cells with actinomycin D. Enhancement of plaque formation by MgCl(2) has been demonstrated to date with 17 rhinoviruses. Some rhinoviruses were enhanced either by DEAE-dextran or by dextran sulfate in the overlay. No inhibitors were found in any of 10 bovine sera tested. Rhinovirus type 2 was visualized inside HeLa cells by electron microscopy and there appeared to be a very high ratio of physical particles per infectious unit of virus. PMID- 4300896 TI - Methods for detecting food-borne enteroviruses. AB - A method previously reported for detecting virus in a model system composed of cottage cheese contaminated with coxsackievirus type A9 has been adapted to detecting selected strains of enteroviruses in a variety of foods. Bentonite is omitted and serum is added for extracting virus from low-protein foods. Samples of foods, usually 25 g, must contain at least 3 to 4 plaque-forming units for a 50% probability of detecting virus. Sensitivity in detecting echovirus type 6 was lower than that for the other viruses used. After extraction from potato salad, poliovirus type 2 was completely reactivated if it had been neutralized with coproantibody, but it was only partially reactivated if neutralized with hyperimmune rabbit serum. PMID- 4300895 TI - Activities of arginine dihydrolase and phosphatase in Streptococcus faecalis and Streptococcus faecium. AB - Strains of Streptococcus faecalis and S. faecium are known to produce ammonia from arginine, but only S. faecalis couples the adenosine triphosphate (ATP) produced through the arginine dihydrolase pathway to growth processes. The specific activities of the arginine dihydrolase enzymes were found to be much lower in S. faecium (0.01 to 0.10) than in S. faecalis (0.24 to 1.60). Phosphatase activities in both strains were similar (up to 0.11), but equaled or exceeded the activities of the arginine dihydrolase enzymes in S. faecium. The failure of S. faecium to show increased growth in arginine media is explained on the basis of low activities of the arginine dihydrolase enzymes coupled with sufficient phosphatase activity to negate any benefit from ATP formed. PMID- 4300897 TI - Susceptibility of salmonellae to cephalosporins and to nine other antimicrobial agents. AB - Three cephalosporin-related antibiotics and nine other antimicrobial agents were studied for in vitro effectiveness against 54 recently isolated strains of Salmonella. Minimal inhibitory concentrations determined by the plate dilution method demonstrated the following percentages of resistance: ampicillin, 6%; tetracycline, 13%; streptomycin, 52%; sulfadiazine, 94%; cephaloglycin, 96%; and lincomycin, 100%. No strains were resistant to cephalothin, cephaloridine, chloramphenicol, colistimethate, kanamycin, and polymyxin B. The commonest serotype studied, S. typhimurium, showed the greatest antibiotic resistance, with 21% resistant to ampicillin, 36% resistant to tetracycline, and 71% resistant to streptomycin. Cephalothin and cephaloridine were highly effective in vitro but inhibitory concentrations of 20 to 40 mug of cephaloglycin per ml were required for the majority of Salmonella strains. PMID- 4300898 TI - Production of reference enteroviruses. AB - Forty-five human enterovirus reagents of certified purity and quality were prepared for use as seed viruses and as immunizing antigens. One of the reagents was ampouled as "untreated" seed virus, whereas 14 were ampouled as "MgCl(2) stabilized" reagents. The remaining 30 reagents were ampouled as "untreated" seed viruses and as "MgCl(2)-stabilized" reagents. Thirty of the reagents were propagated on primary African green monkey kidney cells, 3 on primary baboon kidney cells, 3 on primary rhesus monkey kidney cells, and the remaining 9 on human amnion cells. Forty-two of the viral antigens were concentrated for use in the production of high-titered specific antisera in large animals. PMID- 4300899 TI - Lecithinase activity of mutant and wild strains of Clostridium perfringens. PMID- 4300900 TI - Virucidal properties of dimethyl sulfoxide. PMID- 4300901 TI - The nature of toxins of herpes simplex virus. I. Syncytial giant cell producing components in tissue culture. PMID- 4300904 TI - Drug responses in ganglia perfused with sodium acetate. PMID- 4300903 TI - Studies on the site of replication of vesicular stomatitis virus. PMID- 4300902 TI - A study on the mechanism of polyoma-induced activation of the cellular DNA synthesizing apparatus. Synchronization by FUdR of virus-induced DNA synthesis. PMID- 4300905 TI - Studies on rat paw edema induced by S. aureus. PMID- 4300906 TI - Effect of bretylium tosylate on angiotensin pressor responses in the pithed rat. PMID- 4300907 TI - Antagonistic effects of beta-adreneric blocking agents on responses to adrenaline in vascular smooth muscle. PMID- 4300908 TI - Embolic mononeuropathy and bacterial endocarditis. PMID- 4300909 TI - [Changes in the respiratory organs in experimental dust inhalation with silica aerogel]. PMID- 4300910 TI - [Characteristics of the development of pneumoconiosis during the administration of various dusts (experimental study)]. PMID- 4300911 TI - [Immunomorphologic changes in the organs of white rats in experimental silicosis]. PMID- 4300912 TI - [Cytomegalic pneumonia and focal necrosis of the adrenal glands with calcium deposits in an infant]. PMID- 4300913 TI - [Papillary hidradenoma of the skin]. PMID- 4300914 TI - [Cytomorphologic and histologic characteristics of some forms of primary cancer of the liver]. PMID- 4300915 TI - [Morphologic criteria of the functional activity of the adrenal cortex]. PMID- 4300917 TI - Regulation of pyruvate carboxylase by coenzyme A and acyl coenzyme A thio esters. PMID- 4300918 TI - Investigation of the conformation of beta-diphosphopyridine nucleotide (beta nicotinamide-adenine dinucleotide) and pyridine dinucleotide analogs by proton magnetic resonance. PMID- 4300916 TI - Photochemical and electron transport reactions of bacterial photosynthesis. PMID- 4300919 TI - Glycopeptides from fibrinogen and fibrin. PMID- 4300920 TI - The binding of adenosine triphosphate to myosin. PMID- 4300921 TI - Phosphohydrolase and phosphotransferase activities of intestinal glucose 6 phosphatase. PMID- 4300922 TI - Induction of phosphopyruvate carboxylase in neonatal rat liver by adenosine 3',5' cyclic monophosphate. PMID- 4300923 TI - [On the principle of the information transmission during electric stimulation of the nerve cell]. PMID- 4300924 TI - [Inhibiting effect of of N', N'-anhydrobis(beta-hydroxyethyl)biguanide hydrochloride (ABOB) on the multiplication of Sendai virus (Paramyxovirus parainfluenzaeI) in tissue culture of calf kidney]. PMID- 4300925 TI - Melanoma with a coincidental acoustic neurinoma. Case report. PMID- 4300926 TI - Diagnosis of acoustic neurinoma by pneumoencephalo-roulette tomography. Technical note. PMID- 4300928 TI - [Neural transmission in the longitudinal muscle membrane of annelida]. PMID- 4300927 TI - [The correlation of the secretion of water, salt and protein of the rabbit salivary gland. 1. The changes in water, salt and protein in rabbit saliva after injection of autonomic action drugs and pituitary-adrenal hormones]. PMID- 4300930 TI - Propagation of B77 virus and three strains of Rous sarcoma virus in Japanese quail. PMID- 4300929 TI - Susecptibility of ducklings to different strains of Rous sarcoma virus and to other avian tumour viruses. PMID- 4300931 TI - Biochemical and histochemical of aerobic oxidative metabolism of oral tissues: VI. Oxidase histochemistry of human gingiva--pre and post gingivectomy. PMID- 4300932 TI - Diabetes mellitus: induction in mice by encephalomyocarditis virus. AB - Hyperglycemia and lesions of the pancreatic islets of Langerhans developed in some, but not all, adult mice infected with a variant of the encephalomyocarditis virus. Large amounts of virus were recovered from the pancreas during acute stages of infection. At this time blood glucose concentrations were markedly elevated and the islets of Langerhans exhibited focal necrosis and degranulation of beta cells. Evidence of abnormal glucose metabolism persisted for varying periods after recovery from the infection. The islets of Langerhans of chronically hyperglycemic mice were distorted and decreased in size, and the beta cells were degranulated. Encephalomyocarditis virus appears to cause diabetes mellitus by reducing the mass of functional beta cells of the islets of Langerhans. PMID- 4300933 TI - [Experiences and therapeutic results following conventional roentagen and cobalt 60 teletherapy of malignant kidney and kiney pelvis neoplasms]. PMID- 4300934 TI - [On the characteristics of the common forms of stomach cancer]. PMID- 4300935 TI - [Experiences in recognizing and treating chemodectomas of the carotid gland]. PMID- 4300936 TI - [Clinical experience with the use of Bamfolin. 1]. PMID- 4300937 TI - Herpes simplex infection of the female genital tract. I. Incidence of infection. PMID- 4300939 TI - [Foot-and-mouth disease: a world problem]. PMID- 4300938 TI - Enzymatic degradation and electrophoresis of human angiotensin I. PMID- 4300940 TI - [Studies on live foot-and-mouth disease virus vaccines]. PMID- 4300941 TI - Are observation wards obsolete? A review of one year's experience in an acute male psychiatric admission unit. PMID- 4300942 TI - A clinical investigation of phobias. PMID- 4300943 TI - The action of antibiotics on heteroglucan production by strains of Azotobacteriaceae. PMID- 4300944 TI - Isolation and purification of the D(-)beta-hydroxybutyric dehydrogenase of Azotobacter vinelandii. PMID- 4300945 TI - [Consideration on a case of bronchiolo-alveolar carcinoma]. PMID- 4300946 TI - [Contribution to the morphological and pathogenetic study of myxomatous and myxomatoid tumors of the breast]. PMID- 4300947 TI - [Experience with the cyclophosphamide massive-dose therapy in inoperable bronchial carcinoma]. PMID- 4300948 TI - Mucoepidermoid tumor of lacrimal gland. PMID- 4300949 TI - [Studies on riboflavin tetrabutyrate (B2-But) and its effects on p dimethylaminoazobenzene (DAB) induced hepatoma or degenerated liver of the rat; ESR spectra of the subfraction of lipoperoxide extracted from the liver and several enzyme activities of the same tissue]. PMID- 4300950 TI - Iron-adjuvant interactions observed with diffuse reflectance spectroscopy. PMID- 4300951 TI - Heterogeneous catalysis of aspirin degradation in chloroformic solution and its relationship to the determination of salicylic acid in buffered aspirin products. PMID- 4300952 TI - Quantitative determination of gallamine triethiodide. PMID- 4300954 TI - An outbreak of swine pox-like disease in Tottori prefecture, Japan. PMID- 4300953 TI - [Histochemical and electron microscopic studies on the function and fine structure of human gastric parietal cells]. PMID- 4300955 TI - Hydrogenated pteridine derivatives with high group transfer potential. PMID- 4300956 TI - Pressor response to infusion of angiotensin into the portal vein of the rat. PMID- 4300957 TI - Role of leucocidin and triphosphoinositide in the control of potassium permeability. PMID- 4300958 TI - Isolation of membrane-associated tumour-specific antigens from rat hepatomas induced by aminoazo dye. PMID- 4300959 TI - Double infections of cultured cells. PMID- 4300960 TI - Vitamins, sugars and ethanol metabolism in man. PMID- 4300961 TI - Mechanisms of sustained increases of firing rate of neurones in the rat cerebral cortex after polarization: role of protein synthesis. PMID- 4300962 TI - Density gradient centrifugation of red blood cells carrying the mammary tumour virus. PMID- 4300963 TI - [Carcinogenic mechanisms from the viewpoint of sensitivity to adrenal hormones]. PMID- 4300964 TI - [Morphology of tumor viruses with special reference to type A mouse tumor virus particles]. PMID- 4300965 TI - [Septicemia due to Leptotrichia vaginalis]. PMID- 4300966 TI - Regulation of activity and biosynthesis of enzymes controlling gluconeogenesis and glycolysis. PMID- 4300967 TI - Response of calves to intravenous and repeated intradermal inoculation of bovine papilloma virus. PMID- 4300968 TI - Isolation of a parainfluenza virus from sentry dogs with upper respiratory disease. PMID- 4300969 TI - Relationship of donor age to adsorption of foot-and-mouth disease virus by mouse tissues. PMID- 4300970 TI - [Morphologic aspects of the hypothalamo-hypophyseal neurohumoral transmission (innervational relationships in the neurohypophysis of mammals)]. PMID- 4300971 TI - Nerve compression syndrome in derangements of the proximal and distal radial ulnar joints. PMID- 4300972 TI - Some studies of infectious bovine rhinotracheitis (IBR) virus infection in calves. AB - Six dairy calves, six and one-half to nine months old, were exposed to a strain of infectious bovine rhinotracheitis (IBR) virus of bovine fetal origin by one of the various routes - nasal, vaginal, preputial or contact. Neither after initial exposure nor following challenge of their immunity did any of these animals manifest the IBR respiratory syndrome, although two of them (inoculated per vagina/prepuce) developed pustular vulvovaginitis or balanoposthitis. Also, one five-day old dairy calf which had received colostrum and milk of its IBR-immune dam, was inoculated intranasally with the same strain of IBR virus. This animal exhibited severe signs of IBR. The virus was recovered from all but three of the seven calves after initial exposure and from all but one animal following challenge of their immunity. Immune responses of these calves resembled those of adult cattle. PMID- 4300973 TI - A virus associated with vulvitis and balanitis in the horse-- preliminary report. PMID- 4300974 TI - ESR studies of the role of manganese in the process of ascorbic acid oxidation. PMID- 4300975 TI - Preferential chromosome loss in a Rous rat sarcoma in response to environmental changes. PMID- 4300976 TI - Synergism of the Schmidt-Ruppin strain of the Rous sarcoma virus and cytidine triphosphate in the induction of chromosome breaks in human cultured leukocytes. PMID- 4300977 TI - Mechanism of chromosome breakage--a new theory. PMID- 4300978 TI - Histochemical study of enzyme systems in frozen dried tissue. PMID- 4300981 TI - Observations on fibroma in poultry. PMID- 4300980 TI - [Incorporation of glucose-carbon into the free amino acids of mouse brain under the influence of pyritinol]. PMID- 4300979 TI - [Recovery and characterization of a soluble glucose-6-phosphatase from pig liver]. PMID- 4300982 TI - Psychoanalytic theory of the instinctual drives in relation to recent developments. PMID- 4300983 TI - Structure and amount of positional isomers of monounsaturated fatty acids in human depot fat. AB - Positional isomers of decenoic, dodecenoic, and tetradecenoic acids of human adipose tissue have been separated by gas-liquid chromatography and their amounts determined by oxidative cleavage. The following acids have been shown to be present: 7-decenoic, 8-decenoic, 9-decenoic, 7-, 8-, and 9-dodecenoic, and 7-, 8 , 9-, and 11-tetradecenoic acids. Among all isomers of the even-numbered acids from C(10) to C(18) the cis-9-isomer predominates. With increasing chain length, however, the content of 9-isomer decreases and the number of isomers increases. No 3- or 5-enoic acids could be detected. The origin and biosynthesis of all isomers are discussed. PMID- 4300984 TI - Granular cell myoblastoma of the vulva. PMID- 4300985 TI - Adrenocortical activity of the African. PMID- 4300986 TI - Studies o the levels of 17 hydroxy-corticoids in 24-hour specimens of urine from five quadriplegic patients and two paraplegic patients admitted to the Royal North Shore Hospital, Sydney. PMID- 4300987 TI - Overlapping conformation changes in spin-labeled hemoglobin. PMID- 4300988 TI - Early effects of 3',5'-adenosine monophosphate on the fluxes of calcium end potassium in the perfused liver of normal and adrenalectomized rats. PMID- 4300991 TI - [On biochemistry of malignant growth]. PMID- 4300990 TI - The biological activity of 25-hydroxycholecalciferol, a metabolite of vitamin D3. PMID- 4300989 TI - Polynucleotide sequence homologies among polioviruses. PMID- 4300992 TI - [Differences in replication and transformation effects of polyoma virus in mice, hamsters, and rats]. PMID- 4300993 TI - [Immunological studies on virus and cell interaction with a mouse leukemia virus]. PMID- 4300995 TI - [Data on the determination of ephedrine. II. Determination of the ephedrine content of some drugs by perchloric acid in non-aqueous medium]. PMID- 4300996 TI - [Functional phenomena and disease]. PMID- 4300997 TI - [Cytologic and cytochemical characteristics of the A-cells in the pancreatic islets of Langerhans]. PMID- 4300994 TI - [Relations between Rous sarcoma virus and avian leukosis virus]. PMID- 4300999 TI - Inhibition of the anticoagulant activity of neodymium chloride by sodium pyrophosphate. PMID- 4300998 TI - [On the effect of kinin-hormones on the mechanism of urine dilution and urine concentration. II. Studies during hydropenia and eliguria as well as during osmotic diuresis with hypertonic mannitol solutions]. PMID- 4301000 TI - [The group of Rous sarcoma and leukosis viruses--a survey of the present information on this subject]. PMID- 4301001 TI - Nature of the increase in liver microsomal glucose-6-phosphatase activity during the early stage alloxan-induced diabetes. PMID- 4301002 TI - [Function tests of the adrenal cortex]. PMID- 4301003 TI - Gonadotrophic regulation of precursor incorporation into ovarian RNA, protein, and acid-soluble fractions. I. Effects of pregnant mare serum gonadotrophin (PMSG), follicle-stimulating hormone (FSH), and luteinizing hormone (LH). PMID- 4301004 TI - Sensitivity to angiotensin and adrenocorticotrophic hormone in the sodium deficient rat. PMID- 4301005 TI - Regulation of adrenal growth. Differences in the effects of ACTH in normal and dexamethasone-suppressed guinea pigs. PMID- 4301006 TI - Development of 3T3-like lines from Balb-c mouse embryo cultures: transformation susceptibility to SV40. PMID- 4301007 TI - Membrane glycoprotein biosynthesis: changes in levels of glycosyl transferases in fibroblasts transformed by oncogenic viruses. PMID- 4301008 TI - [The immunity phenomenon and neuromuscular diseases]. PMID- 4301009 TI - [Diagnosis and management of drug allergy]. PMID- 4301010 TI - [Autopsy case of acromegaly with cardiomegaly]. PMID- 4301011 TI - [My field of research--basic and applied neurophysiology]. PMID- 4301013 TI - Cancer of the male breast. A report of 40 cases. PMID- 4301014 TI - [Variation in the depression of radiation-induced mitosis arrest through addition of a nicotinic acid derivative]. PMID- 4301012 TI - Characteristics of REM sleep following different conditioned rates of waking eye movement in the monkey. PMID- 4301015 TI - [Study of the splanchnic circulation and its changes induced by the action of adrenaline, noradrenaline and hypertensin]. PMID- 4301016 TI - [The action of various hypophyseal peptides on the Variations of free fatty acids in the perfusion system of the isolated rat liver]. PMID- 4301017 TI - [Histochemical activity changes of some enzymes of the citric acid cycle and the succinic oxidase system in various organs of the rat following whole-body irradiation]. PMID- 4301018 TI - [Appraisal of the radiation changes and metastatic lesions of the lymphatic system of the pelvis with the aid of lymphography]. PMID- 4301019 TI - [Induction of tumors in monkeys with Rous virus]. PMID- 4301020 TI - [On chicken immunity in Rous sarcoma]. PMID- 4301022 TI - Migration of radiation damage in DNA. PMID- 4301021 TI - [The influence of STH and ACTH on the antitumor effect and toxicity of dipin in hypophysectomized rats with sarcoma 45]. PMID- 4301024 TI - Gas gangrene of the anterior abdominal wall. PMID- 4301023 TI - Cinecystourethrography in patients with spinal cord injuries. PMID- 4301025 TI - Bacterial cytochromes. PMID- 4301026 TI - The poxviruses. PMID- 4301027 TI - The oncogenic DNA viruses: a review of in vitro transformation studies. PMID- 4301029 TI - Criteria for assessing effects of drugs on postsynaptic inhibition. PMID- 4301030 TI - [Neuronal structure and interneuronal connections in the visual cortex of the pig]. PMID- 4301028 TI - [Actions of diazoxide on the cardiovascular system, on the metabolism of the myocardium and on sympathetic discharges]. PMID- 4301031 TI - [Laboratory diagnosis of infectious bovine rhinotracheitis (BR)]. PMID- 4301032 TI - [On the demonstration of Clostridium (C1.) welchii toxin with the intracutaneous test in immunized guinea pigs]. PMID- 4301033 TI - [Studies on the occurrence of adenovirus antibodies in pigs of various ages]. PMID- 4301034 TI - [Chemotherapeutic studies on advanced tuberculosis in mice]. PMID- 4301035 TI - The effect of encephalomyocarditis-virus ribonucleic acid on amino acid incorporation in two mammalian cell-free protein-synthesizing systems. PMID- 4301036 TI - The solubilization and partial fractionation of the thiol components of isolated nuclei. PMID- 4301038 TI - Studies on isoniazid-copper interaction. PMID- 4301037 TI - The mechanism of thyrotrophin action in relation to lipid metabolism in thyroid tissue. AB - 1. The effects of thyrotrophin in vitro on the incorporation of [(14)C]-glucose, glycerol, -palmitate and -oleate into the lipids of thyroid tissue were examined. 2. Thyrotrophin increased the incorporation of these (14)C-labelled precursors into phosphatidylinositol specifically. 3. Thyrotrophin also increased the proportion of (14)C radioactivity from labelled glucose, glycerol, palmitate and oleate incorporated into the 1,2-diglycerides. 4. The addition of thyrotrophin to thyroid slices for 10min., after 2hr. of prelabelling with [(14)C]glycerol, also increased the proportion of (14)C radioactivity incorporated into the 1,2 diglyceride fraction. 5. After incubation of thyroid tissue with [1 (14)C]palmitate, thyrotrophin caused a two- to three-fold increase in the specific radioactivity of palmitate isolated from phosphatidylinositol and 1,2 diglycerides. In contrast, the specific radioactivity of palmitate isolated from the choline and ethanolamine phosphoglycerides, 1,3-diglycerides and triglycerides was not increased by thyrotrophin. PMID- 4301040 TI - Studies of an established canine kidney-cell line. PMID- 4301039 TI - Enzyme studies on the esterification of vitamin D in rat tissues. AB - 1. The mechanism of vitamin D esterification in the rat was studied with liver, small-intestinal mucosa, pancreatic juice and blood plasma as enzyme sources and [1-(3)H]cholecalciferol, [U-(14)C]ergocalciferol and [4-(14)C]cholesterol as substrates. 2. No esterification of vitamin D could be detected with liver preparations nor with homogenates or acetone-dried powder extracts of intestinal mucosa. 3. Pancreatic juice esterified [1-(3)H]cholecalciferol with oleic acid, and specificity studies indicated that a cholesterol-esterifying enzyme was using vitamin D as substrate. 4. Plasma cholesterol-esterifying enzyme also esterified vitamin D. 5. The specificity of the esterification reaction is discussed in relation to (a) the molecular structure of the substrates and (b) their availability, in a micellar solution, to the enzyme. 6. It is concluded that cholesterol-esterifying enzymes esterify vitamin D in vivo during absorption from the small intestine and while it is transported in blood. PMID- 4301041 TI - [Collision tumors of the lung]. PMID- 4301042 TI - Sedimentation pattern of soluble protein from thyroids of iodine deficient rats; acute effects of iodide. PMID- 4301043 TI - Steoid delta-isomerase of the bovine adrenal gland: kinetics, activation by NAD and attempted solubilization. PMID- 4301044 TI - Mixed cryoimmunoglobulinaemia in infectious mononucleois and Cytomegalovirus mononucleosis. PMID- 4301045 TI - Proline as an intermediate in the reductive deamination of ornithine to delta aminovaleric acid. AB - Fresh extracts of cells of Clostridium botulinum reduced a limited amount of ornithine to delta-aminovaleric acid, but at high substrate concentrations a considerable amount of an amino compound accumulated which was neutral at pH 4.2. Aging of the extracts at -10 C or freezing and thawing resulted in the loss of the ability to produce delta-aminovaleric acid, but the ability to produce the neutral compound was retained. This compound was separated by column chromatography, and was found to be identical to dl-proline with respect to (i) R(F) upon paper chromatography, (ii) migration rates upon paper ionophoresis, (iii) spectrum of the product of the ninhydrin reaction, (iv) oxidation with d amino acid oxidase, and (v) rate of reduction to delta-aminovaleric acid by cell extracts. The intermediate role of proline in the reduction of ornithine to delta aminovaleric acid was indicated by (i) rate studies with and without an added electron donor and with and without inhibitors of proline reductase, (ii) the initial accumulation of radioactive proline to the exclusion of radioactive delta aminovaleric acid from (14)C-l-ornithine in the presence of low levels of carrier proline, and (iii) the initial accumulation of proline at low levels prior to a significant accumulation of delta-aminovaleric acid in reaction mixtures in which the latter compound was the primary product after a longer incubation time. The conversion of ornithine to proline was the rate-limiting step in the presence of a good electron donor (alanine). The mechanism of the conversion of ornithine to proline has not been established. Preliminary data indicated that it may involve an oxidation to glutamic-gamma-semialdehyde and its equilibrium product, Delta(1) pyrroline-5-carboxylic acid. PMID- 4301046 TI - Site in cell-free protein synthesis sensitive to diphtheria toxin. AB - The effects of diphtheria toxin on cell-free protein synthesis in a bacterial system, and preparations obtained from animals that were sensitive and resistant to toxin were examined. In the presence of nicotinamide adenine dinucleotide (NAD), toxin inhibited the incorporation of amino acids by endogenous and synthetic polynucleotides in both rat liver and guinea pig liver cell-free systems that were exposed to 6 Lf units per ml of toxin. A cell-free system derived from Streptococcus faecalis was resistant to high concentrations of toxin. Dialyzed toxin-antitoxin floccules that are formed in the presence of NAD and the 105,000 x g supernatant fluid from rat liver contain NAD. Such floccules are also active in protein synthesis in the absence of added transferase I or II. An operational model presents the view that the intoxication complex is formed at the ribosomal level and occurs in two steps. First, the toxin molecule binds to transferase II and alters its stereospecific relationship to transferase I, but it does not result in an inactive complex. Second, the stereospecific alteration in transferase I, but it does not result in an inactive complex. Second, the stereospecific alteration in transferase II caused by the binding of diphtheria toxin allows NAD to bridge between transferase I and II, which then results in an inactivated complex. The sensitivity of the cell-free system derived from the normally resistant rat implies that in some cells the cell membrane serves as a permeability barrier to the toxin molecule. The resistance of bacterial cell-free protein synthesizing systems to diphtheria toxin may reflect basic differences between transferase enzymes from bacterial and mammalian sources. PMID- 4301047 TI - Staphylococcal hyaluronate lyase: purification and characterization studies. AB - Staphylococcal hyaluronate lyase (hyaluronidase) derived from a pathogenic strain of staphylococcus was purified by means of salt fractionation with ammonium sulfate and gel filtration through Sephadex G-100. Most of the enzyme activity from concentrated culture supernatant fluids of staphylococci was obtained in a fraction precipitated by 90 to 100% saturation with ammonium sulfate. A small amount of enzyme was also precipitated by 80 to 90% saturation with the salt. The hyaluronidase-rich fractions did not contain other staphylococcal enzymes, such as coagulase, protease, lipase, and staphylokinase. These enzymes were present in the original concentrates. Molecular sieving chromatography of the partially purified enzyme by filtration through Sephadex G-100 resulted in a further increase in specific enzyme activity. However, more than one active peak was obtained after gel filtration, thus suggesting that there may be more than one molecular form of the enzyme. Immunodiffusion in agar gel of the chromatographically purified enzyme fraction, with immune serum from rabbits injected with concentrated staphylococcal culture supernatant fluids, indicated that there was one major antigen. A similar antigen, giving reactions of identity with the purified material, was present in the original culture supernatant fluid. PMID- 4301049 TI - Combined surgical-radiological treatment of parotid gland fistulae. PMID- 4301048 TI - Tumours and other diseases of the salivary glands in relation to general physiology and pathology. PMID- 4301050 TI - Radioautographic study of epidermal cell proliferation and migration in normal and neoplastic tissues of rabbits. PMID- 4301051 TI - Interferon response and age-related resistance of germfree mice to mouse hepatitis virus. PMID- 4301052 TI - Effects of cortisone on interferon response of germfree mice to mouse hepatitis virus. PMID- 4301053 TI - Paraganglioma (chemodectoma) of the middle ear and mastoid. PMID- 4301054 TI - [Errors in the diagnosis of insuloma]. PMID- 4301056 TI - [The extraction and chemical purification of the antibiotic florimycin]. PMID- 4301055 TI - [On the angiotensin resistance of non-hypertensive types of chronic pyelonephritis]. PMID- 4301057 TI - [Treatment with pituitary stimulation in rheumatoid arthritis. Physiopathological and clinical data on posterior-pituitary opotherapy]. PMID- 4301058 TI - Morphological conversion, hyperconversion and reversion of mammalian cells treated in vitro with N-nitrosomethylurea. PMID- 4301059 TI - Assessing skeletal maturity: comparison of the atlas and individual bone technics. PMID- 4301060 TI - Cytochrome as a guide to classifying bacteria: taxonomy of Microbacterium thermosphactum. PMID- 4301061 TI - Production of self-directed antibody by tumour cells. PMID- 4301062 TI - Vinca alkaloid neuropathy: nerve biopsy studies in rats and in man. PMID- 4301063 TI - Glucose metabolism in five neuromuscular disorders. PMID- 4301064 TI - [Ultrastructural study of Masson's glomus tumor. Anatomo-clinical report]. PMID- 4301065 TI - [A new technic of myeloradiculography with resorbable hydrosoluble iodized contrast medium without spinal anesthesia]. PMID- 4301066 TI - [Destruction of the foot-and-mouth disease virus in milk products through temperature]. PMID- 4301067 TI - [Studies on the reduction of pulmonary volume through excitment and its hormonal control in the horse]. PMID- 4301068 TI - Herpetic keratoconjunctivitis: therapy with synthetic double-stranded RNA. AB - A study was undertaken in rabbits to determine how late in the course of keratoconjunctivitis caused by herpes simplex recovery could be effected by an inducer of interferon. Interferon was induced by means of synthetic double stranded RNA copolymer formed with polynosinic acid: polycytidilic acid RNA. Therapy promotes recovery from severe and fully established keratoconjunctivitis for which treatment was begun as late as 3 days after virus inoculation. No drug toxicity was observed in the therapeutic dose range. These findings further support the proposed role of the interferon mechanism in the natural recovery of already established viral infection. They also suggest the usefulness of interferon inducers in viral infections of man. PMID- 4301069 TI - Chromatographic separation and photometric analysis of the components of Nile blue sulphate. PMID- 4301070 TI - Arrhenoblastoma in an Indian Desi hen. PMID- 4301071 TI - Studies on acute Marek's disease. I. Characteristics of isolate GA in chickens. PMID- 4301072 TI - Survival of Marek's disease agent in litter and droppings. PMID- 4301073 TI - Surface properties of acidic phospholipids: interaction of monolayers and hydrated liquid crystals with uni- and bi-valent metal ions. PMID- 4301074 TI - Isolation of a membrane fraction enriched in nerve-end membranes from rat brain by zonal cetrifugation. PMID- 4301075 TI - Human liver glucose-6-phosphatase: characteristics of the detergent-solubilized enzyme. PMID- 4301076 TI - The reaction between NAD+ and rabbit-muscle glyceraldehydephosphate dehydrogenase. PMID- 4301077 TI - Serological survey of human arbovirus infections in Southeastern British Columbia. PMID- 4301078 TI - Self-induced waking: changes in dreams and sleep patterns. PMID- 4301079 TI - [Treatment with new antitubercular agents]. PMID- 4301080 TI - [A 5-year period (1961-65) of activity of the dispensary of mental health and mental prophylaxis in the province of Pescara]. PMID- 4301081 TI - Current trends in group therapy with children. PMID- 4301082 TI - The interconnexions of the muscle layers of the human colon. PMID- 4301083 TI - [Cerebral gamma-planigraphy with radioiodide serum albumin (RISA)]. PMID- 4301085 TI - [The mammary tumor virus]. PMID- 4301084 TI - Hand, foot and mouth disease in South Australia. PMID- 4301086 TI - Inhibitor of antibiotics in bacteriologic agar. PMID- 4301087 TI - A new overlay for plaquing animal viruses. PMID- 4301088 TI - Age difference in the intestinal phosphomonoesterase activity of mice. PMID- 4301089 TI - Inhibition of adrenal steroidogenesis by glutethimide. PMID- 4301090 TI - Fetal and maternal responses to in utero angiotensin infusions in Macaca mulatta. PMID- 4301091 TI - Prevention of viral and transplant tumors in hamsters employing killed and fragmented homologous tumor cell vaccines. PMID- 4301092 TI - [Difficulties in the diagnosis of various tumorous kidney affections in childhood]. PMID- 4301093 TI - [Basis of multielectrode technic and its clinical significance]. PMID- 4301094 TI - [Effects of valium in the course of various phases of spontaneous night sleep]. PMID- 4301095 TI - Study of forced circus movements. PMID- 4301096 TI - NAD-ase activity and glycolysis in Ehrlich-Lettre carcinoma and liver cell particulates. PMID- 4301097 TI - Hydrolysis of higher fatty acid esters of p-nitrophenol by rat liver and kidney lysosomes. PMID- 4301098 TI - [Study of cell changes in wound infiltrate in tissue culture in the organism]. PMID- 4301099 TI - [The effect of adrenocorticotrophic hormone of the hypophysis on the reparative process in the adrenal cortex]. PMID- 4301100 TI - [The effect of lactoflavin, nicotinic acid amide or dipyridamol on the cancerogenic action of diethylnitrosamine in rats]. PMID- 4301101 TI - [Hemodynamic mechanisms of arterial hypotension present during desynchoronized sleep in the cat]. PMID- 4301102 TI - [Behavior of coronary vascular resistance in experimental coronary insufficiency. Preliminary note]. PMID- 4301103 TI - Interstitial pulmonary fibrosis, atypical epithelial changes and bronchiolar cell carcinoma following busulfan therapy. PMID- 4301104 TI - Carcinoma of the pancreas. Results of treatment. PMID- 4301105 TI - [On the association of a histiocytoma with a basalioma]. PMID- 4301106 TI - New method for isolating nicotinamide-adenine dinucleotide (NAD) from baker's yeast. PMID- 4301107 TI - [Metabolic problems of high altitude adaptation]. PMID- 4301108 TI - [Carcinoma of the male breast]. PMID- 4301109 TI - Immune paralysis of thymus cells by bovine serum albumin. PMID- 4301110 TI - Photometric demonstration of aggregation of slime mould cells showing effects of temperature and ionic strength. PMID- 4301111 TI - Habituation in relation to state in the human neonate. PMID- 4301112 TI - [Studies on the nature of the substance responsible for the inhibition of O streptolysin in the serum of mice with virus hepatitis MHV-3 and with necrosis form CCl4]. PMID- 4301113 TI - [Viral synthesis in cells infected simultaneously with guanidine sensitive and guanidine dependent poliovirus]. PMID- 4301114 TI - [Atypical localization of a Barre-Masson tumor]. PMID- 4301115 TI - [Glomus tumor of the stomach (1 case)]. PMID- 4301116 TI - [On the histogenesis of ovarian tumors (experimental study)]. PMID- 4301117 TI - [On the products of hydrolysis of DNA with extracts from tumors]. PMID- 4301118 TI - [Comparative cytomorphologic study of cell cultures following infection with various strains of herpes simplex virus]. PMID- 4301119 TI - [Inhibitory effect of 6-azauridine on the reproduction of herpes simplex virus]. PMID- 4301120 TI - [Dynamics of the formation of viral proteins in amniotic cells infected with adenovirus types 4 and 7]. PMID- 4301121 TI - [Reproduction of various viruses in leukocyte cultures]. PMID- 4301122 TI - [Polymers for the purification and concentration of virus preparations]. PMID- 4301123 TI - [Experimental study of antibody changesin successive immunization of rats with influenza virus A2 and parainfluenza virus types 1-3]. PMID- 4301124 TI - [Immunoreactivity of the lymphoid organs of a non-susceptible animal following inoculation with poliomyelitis virus]. PMID- 4301125 TI - [The relationship between the dose of virus OV4O (SV4O) and the rapidity of onset of the cytopathic effect in tissue culture]. PMID- 4301126 TI - [Morphologic anc cytochemical study of leukemia cells sensitive and resistant of Coxsackie B3 virus]. PMID- 4301127 TI - [Inhibitors of adenovirus hemagglutination and spontaneous hemagglutinins in the sera of animals and humans]. PMID- 4301128 TI - [Experimental rhinovirus infection in man]. PMID- 4301129 TI - [Arteriosclerosis and calciphylaxis]. PMID- 4301130 TI - [On recognition of lung chemodectomas]. PMID- 4301131 TI - [Cytomegaly in adults]. PMID- 4301132 TI - [Lymph node findings in asbestosis]. PMID- 4301133 TI - The cryptophthalmos-syndactyly syndrome. PMID- 4301134 TI - Malignant mesodermal mixed tumor (mesenchymoma) of the orbit. PMID- 4301135 TI - Treatment of nephoroblastoma (Wilms' tumour). PMID- 4301136 TI - The oxidized forms of cytochrome oxidase. PMID- 4301137 TI - Retailing of barbecued chickens--a Canadian survey. PMID- 4301138 TI - Effect of some mutagenic virogens and carcinogens on deoxyribonucleic acid. PMID- 4301139 TI - [Histochemical study of uterine muscle: glucose-6-phosphatase]. PMID- 4301140 TI - [Observations of breast cancer during pregnancy and the lactating period]. PMID- 4301141 TI - [3 cases of bilateral breast cancer]. PMID- 4301143 TI - [Study of neural tumors produced by the administration of methylnitrosourea to rats]. PMID- 4301142 TI - [Value of the evaluation of antidiuretic secretions for the diagnosis of the maliganancy of brain tumors]. PMID- 4301144 TI - [Correlation of microelements and the activity of respiratory enzymes during acute hypoxic hypoxia]. PMID- 4301145 TI - [On changes in activity of several respiratory enzymes and tissue respiration in liver under the influence of various pathogenic factors]. PMID- 4301146 TI - Proteins in bioelectricity: the control of ion movements across excitable membranes. PMID- 4301147 TI - Enzyme secretion in mouse pancreas mediated by adenosine-3'5'-cyclic phosphate and inhibited by adenosine-3'-phosphate. PMID- 4301148 TI - Spin-labeled mitochondrial lipids in Neurospora crassa. PMID- 4301149 TI - Changes in fluorescence, turbidity, and birefringence associated with nerve excitation. PMID- 4301150 TI - [Magnetic resonance absorption in organisms]. PMID- 4301151 TI - [Experimental research with a new opaque contrast medium (Duroliopaque)]. PMID- 4301152 TI - [Results of cortisone withdrawal in 58 cases of rheumatoid polyarthritis]. PMID- 4301153 TI - [Faculte Mixte de Medecine et de Pharmacie de Rennes. Chair of Neurology and Psychiatry. Inaugural lesson]. PMID- 4301154 TI - [Intestinal endometriosis]. PMID- 4301155 TI - [Surgical treatment of mitral valve diseases in children]. PMID- 4301156 TI - [Treatment of interventricular communication in children]. PMID- 4301157 TI - [Postpartum metrorrhagia due to drugs administered during pregnancy and postpartum]. PMID- 4301158 TI - [Study of 100 cases of angina treated by amiodarone]. PMID- 4301159 TI - [Animal experimental studies on various smallpox vaccines in a cowpox challenge experiment on white mice]. PMID- 4301160 TI - Composition and structure of urinary stone. PMID- 4301161 TI - Adenovirus type 3 epidemic associated with intermittent chlorination of a swimming pool. PMID- 4301162 TI - Fibrosis in coal workers. PMID- 4301163 TI - Quartz content in fibrosis. PMID- 4301165 TI - Pontine relay from cerebral cortex to cerebellar cortex and nucleus interpositus. PMID- 4301164 TI - [Sexual excitement in the rabbit caused by intraventricular injection of ACTH]. PMID- 4301166 TI - Direct inhibitory innervation of teleost oculomotor neurons by cerebellar Purkinje cells. PMID- 4301167 TI - Excitability changes in dendrites of thalamic neurons during prolonged synaptic activation. PMID- 4301168 TI - Synaptic action of specific visual inpulses upon cat's parastriate cortex. PMID- 4301169 TI - The nature of tetraplegia in infectious tetanus. PMID- 4301170 TI - EMG analysis of myasthenic ACTH deterioration. PMID- 4301171 TI - Action of tetrodotoxin on spinal motoneurons of the cat. PMID- 4301172 TI - Analysis of spontaneous subthreshold activity in spinal motoneurons of the cat. PMID- 4301173 TI - Behavioral effects of electrical stimulation of group I muscle afferents in acute thalamic cats. PMID- 4301174 TI - Contrasting effects of two identified amygdaloid efferent pathways on single hypothalamic neurons. PMID- 4301175 TI - Receptive fields of single optic nerve fibers in a mammal with an all-cone retina. II: directionally selective units. PMID- 4301176 TI - [On primary malignant tumors of the biliary ducts at the hilar level]. PMID- 4301178 TI - BHK 21 cell cultures for the large-scale production of foot-and-mouth disease virus. PMID- 4301177 TI - Hypernatremia due to hypodipsia and elevated threshold for vasopressin release. Effects of treatment with hydrochlorothiazide, chlorpropamide and tolbutamide. PMID- 4301179 TI - Latent ECSO virus infections of sucking pigs. I. Isolation of latent enteroviruses from tissue cultures, obtained from kidneys of apparently healthy sucking pigs. PMID- 4301181 TI - [A pock-like disease in the rhinoceros (Diceros bicornis L.)]. PMID- 4301180 TI - Epizootiological aspects of the presence of haeminhibiting (HI) antibodies agianst viruses influenza A10equine (Prague) 56 and Parainfluenza 3(PI 3) in horse sera in Croatia. PMID- 4301182 TI - [The illusion of attenuated foot-and-mouth disease virus by interference between avirulent and virulent virus of the same strain]. PMID- 4301183 TI - [Studies on the formation of precipitating antibodies in pock diseases in pigeons]. PMID- 4301184 TI - Aglossia-adactylia syndrome. PMID- 4301185 TI - Wilms' tumor, congenital heart defects, pheochromocytomas and thyroid cancer. PMID- 4301186 TI - Effect of adrenergic agents on toad bladder response to ADH, 3',5'-AMP, and theophylline. PMID- 4301187 TI - Cytomegalovirus mononucleosis. PMID- 4301188 TI - [Development of resistance to nalidixic acid in experiments in vitro and cross resistance with other preparation in pathogenic and nonpathogenic strains of E. coli]. PMID- 4301189 TI - Plasma cell and lymphocytic reaction in the Syrian hamster to transplanted homologous tumor cells transformed in vitro "spontaneously" or by SV 40. PMID- 4301190 TI - Neoplastic transformation induced by simian virus 40 in Syrian hamster neuroglial and meningeal cell cultures. PMID- 4301191 TI - Studies of the resistance and susceptibility to viral superinfection of adenovirus 12 hamster tumor cells. PMID- 4301192 TI - Polyoma virus infection in neonatally thymectomized hamsters. PMID- 4301194 TI - The weeping mother, an unusual source of variola virus. PMID- 4301193 TI - Some behavioral studies of simian virus 40 (SV 40). PMID- 4301195 TI - A virus disease of captive vervet monkeys (Cercopithecus aethiops) caused by a new herpesvirus. PMID- 4301197 TI - Search for a human leukemia virus. PMID- 4301196 TI - The search for human hepatitis viruses. PMID- 4301198 TI - Intrinsic interference: a unique interference system used in assaying non cytopathic viruses. PMID- 4301200 TI - Plaque variants by Sindbis virus. PMID- 4301199 TI - Studies on human adenoviruses as inducers of interferon in chick cells. PMID- 4301201 TI - The adsorption and elution of parainfluenza 2 virus. PMID- 4301202 TI - [The pathological anatomy of pemphigus in connection with its treatment with steroid hormones]. PMID- 4301203 TI - [Histochemical peculiarities of mucus and changes in collagen in the mucous form of cancer of the large intestine]. PMID- 4301207 TI - Infusion of liver tumours. PMID- 4301208 TI - The inhibition of mammalian mitochondrial NADH oxidation by chloramphenicol and its isomers and analogues. PMID- 4301209 TI - Nucleotide clusters in deoxyribonucleic acids. I. Isolation of purine oligonucleotides. PMID- 4301210 TI - Two deoxyribonucleases from Novifoff ascites hepatoma cells. PMID- 4301211 TI - Reversal of mitochondrial swelling associated with fatty acid oxidation. II. Effects of cytochrome c and carnitine on contraction of fatty acid swollen mitochondria. PMID- 4301213 TI - Regulatory interactions of dehydroepiandrosterone and its sulfate in rat testis tissue. PMID- 4301212 TI - Studies on the chemical constitution of cell-wall lipopolysaccharides from Neisseria perflava. PMID- 4301214 TI - The proteins of rapeseed (Brassica napus L.) soluble in salt solutions. PMID- 4301215 TI - Gluconeogenesis in rats during cold acclimation. PMID- 4301216 TI - [Early stages of healing of damaged dental pulp in the light of morphological and histochemical studies]. PMID- 4301217 TI - Body motility during sleep and its relation to the K-complex. PMID- 4301218 TI - Changes in phosphatase enzymes following denervation of the vallate papilla of the rat. PMID- 4301219 TI - Emetine on adrenergic transmission. PMID- 4301220 TI - [Modifications of carbohydrate metabolism observed during hepatocarcinogenesis by DAB. II. Modification of the relative role of the Embden-Meyerhof pathway]. PMID- 4301221 TI - An investigation of the mechanifm of the luminescent peroxidation of luminol by stopped flow techniques. PMID- 4301222 TI - Studies on cytochrome c peroxidase. XII. Crystalline synthetic enzymes containing unnatural heme prosthetic groups. PMID- 4301223 TI - Inosinic acid dehydrogenase of sarcoma 180 cells. PMID- 4301224 TI - Studies on mutarotases. II. Investigations of possible rate-limiting anomerizations in glucose metabolism. PMID- 4301225 TI - The purification and properties of rat liver nicotinamide adenine dinucleotide kinase. PMID- 4301226 TI - The occurrence of diphosphoinositide and triphosphoinositide in Saccharomyces cerevisiae. PMID- 4301227 TI - Purification and properties of deoxyribonucleic acid polymerase from rat liver mitochondria. PMID- 4301228 TI - The occurrence of autoacceleration during hydrolysis of nucleic acids by micrococcal nuclease. PMID- 4301229 TI - Functional consequences of modification of kidney fructose 1,6-diphosphatase by pyridoxal 5'-phosphate. PMID- 4301230 TI - [Multiple glomic tumors (bilateral glomus jugulare associated with a carotid glomus). Apropos of a case]. PMID- 4301231 TI - Slow synaptic responses and excitability in sympathetic ganglia of the bullfrog. PMID- 4301232 TI - Intracellular analysis of slow inhibitors and excitatory postsynaptic potentials in sympathetic ganglia of the frog. PMID- 4301233 TI - Effect of atropine on the latency of cochlear potentials. PMID- 4301234 TI - [Critical study of the angiotensin perfusion test]. PMID- 4301236 TI - [Bilateral Wilms' tumor]. PMID- 4301235 TI - "Trophic" influences of nerve on muscle. PMID- 4301237 TI - Specificity of ribonuclease Ch from Chalaropsis species. AB - A ribonuclease is produced by the fungus Chalaropsis sp. that appears to have an absolute specificity for 3'-guanylic acid residues in ribonucleic acid. PMID- 4301238 TI - [Non-atheromatous stenosis of the digestive arterial trunks]. PMID- 4301239 TI - [Familial dyschondrosteosis. Study of 3 cases (mother and her 2 sons)]. PMID- 4301240 TI - [Scintigraphy in the diagnosis of jaundice]. PMID- 4301241 TI - [Diazepam anesthesia in the practice of external electric shock]. PMID- 4301242 TI - Testosterone production by rabbit testis slices. PMID- 4301243 TI - [Respiratory phosphorylation and energy of activation of phosphatase in roots of tobacco infected with tobacco mosaic virus]. PMID- 4301244 TI - [Use of cortisol and its derivatives in clinic practice]. PMID- 4301245 TI - ["Epilepsy" and hypoglycemic syndrome in tumor of the pancreatic islet tissue]. PMID- 4301246 TI - [Carcinogenic nitrosamines]. PMID- 4301247 TI - [The importance of various tonic reflexes in the differentiation of tumors of the frontal lobe]. PMID- 4301248 TI - [Virus neutralizing and antibrain antibodies in multiple sclerosis and multiple encephalomyelitis]. PMID- 4301249 TI - Corticotrophin treatment in multiple sclerosis. PMID- 4301250 TI - Mast cells in INH-induced neuropathy of the rat. PMID- 4301251 TI - Influence of corticosteroids on the hypothalamic control of sciatic-evoked potentials in the brain stem reticular formation and the hypothalamus in the rat. PMID- 4301252 TI - Effect of muscular exertion on the reaction of the pituitary-adrenocortical axis in trained and untrained rats. PMID- 4301254 TI - Ethanol-induced hypoglycemia. PMID- 4301255 TI - Reflux pancreatography. An evalauation of contrast agents for studying the pancreas. PMID- 4301256 TI - Peritoneal extravasation of oily contrast medium following lymphography. PMID- 4301257 TI - Liver scans in children: abdominal masses simulating metastatic disease. PMID- 4301258 TI - Submaxillary sialography in combination with pneumoradiography and tomography. PMID- 4301260 TI - [X-ray induced changes of the antigenic structure of ascites tumor cells in the rat studied with immunofluorescence]. PMID- 4301259 TI - Aldosterone production after suppression of corticotropic secretory activity. PMID- 4301261 TI - Sleep and birbiturates: some experiments and observations. AB - To determine the effect of barbiturates on sleep two subjects, after a control period, received 200 mg. of sodium amylobarbitone for 26 nights. All night sleep records taken during this period showed that the barbiturate shortened the delay to sleep, increased the total sleep period, lengthened the delay to rapid eye movement (R.E.M.) sleep, and depressed R.E.M. sleep. After five nights R.E.M. sleep returned to baseline values -that is, showed tolerance. On stopping the drug withdrawal phenomena were seen, even to this small dose of the drug.In a second experiment a subject dependent on 600 mg. of Tuinal was found to have low normal R.E.M. sleep while on drugs. On withdrawal, delay to sleep increased and total sleep time fell. R.E.M. sleep was doubled and the delay to R.E.M. became abnormally short.These findings suggest that hypnotics allow sleep to be "borrowed," and that patients should be supported while they are being withdrawn. PMID- 4301262 TI - Peripheral neuropathy in metachromatich leucodystrophy. PMID- 4301263 TI - Treatment of vitiligo. PMID- 4301264 TI - [Histomorphology and cytochemistry of experimental beryllium granulomas in the guinea pig skin]. PMID- 4301265 TI - [Hidradenoma papilliferum. An enzym histochemical and electron microscopic study]. PMID- 4301266 TI - Synovial sarcoma in Indians. (Observations on 22 cases with an emphasis on morbid anatomy). PMID- 4301267 TI - Immunological studies with human breast tumours. PMID- 4301268 TI - Comparative metabolic studies on the ovaries of the mice susceptible and resistant to breast cancer. PMID- 4301269 TI - Hepatoblastoma of the liver. (Report of a case). PMID- 4301270 TI - [Renovascular hypertension]. PMID- 4301272 TI - Chromosome pulverization in chinese hamster cells induced by Sendai virus. PMID- 4301271 TI - The relative sensitivity of various reagents for the detection and differentiation of sugars and sugar derivatives in glycoproteins. PMID- 4301273 TI - Cellular phase of chromosome pulverization induced by Sendai virus. PMID- 4301274 TI - Experimental aerosol transmission of Yaba virus in monkeys. PMID- 4301275 TI - Immunologic response of monkeys to aerosols of Yaba virus. PMID- 4301276 TI - [On symptomatology and diagnosis of generalized cytomegalic inclusion disease in pregnant women]. PMID- 4301277 TI - [On the technic of tryptophan-perchloric acid reaction]. PMID- 4301278 TI - The role of potassium and calcium ions in the effect of epinephrine on cardiac cyclic adenosine 3',5'-monophosphate, phosphorylase kinase, and phosphorylase. PMID- 4301280 TI - [Cytomegalovirus mononucleosis following blood transfusion]. PMID- 4301279 TI - [Isolation of adenovirus type 8 in patients with epidemic keratocojunctivitis]. PMID- 4301281 TI - [Methyl bromide poisoning]. PMID- 4301282 TI - [Methyl bromide poisoning]. PMID- 4301283 TI - [A new light on the etiology of periodontal diseases?]. PMID- 4301284 TI - Functional classification of glioblastoma. PMID- 4301285 TI - [Cancer and virus]. PMID- 4301286 TI - [On regulation of the daily rhythm of adrenal cortex hormones in corticosteroma]. PMID- 4301287 TI - [On the reaction of basophil and eosinophil leukocytes to hormones and heparin]. PMID- 4301288 TI - [A method of biological standardization of ACTH by cross trials on intact rats]. PMID- 4301289 TI - [The clinico-radiologic characteristics of the status of the skeleton in the neuroendocrine form of the diencephalic syndrome (Itsenko-Cushing type)]. PMID- 4301290 TI - [The effect of certain corticoids and ACTH on the functional activity of the thyroid gland under experimental conditions and in clinical patients]. PMID- 4301291 TI - [The effect of cortisone on the level of oxidized and reduced forms of nicotinamide-adenine dinucleotide in rat liver homogenate and on the optic density of mitochondria]. PMID- 4301293 TI - [Participation of the adrenal glands and the adrenocorticotropic hormone of the pituitary gland in the change in phagoccytic activity of rat blood leukocytes during the action of strong sound stimulus]. PMID- 4301292 TI - [The role of the adrenal glands in adaptive reactions in the chilling of newborn animals in the process of development of their reactivity]. PMID- 4301294 TI - [Acid phosphomonoesterase activity in the adrenal glands in experimental hypercholesteremia]. PMID- 4301295 TI - [A study of cholesterol biosynthesis in the rat liver after stimulation of the adrenal cortex with ACTH]. PMID- 4301296 TI - Cancer of the prostate:estrogen therapy: natural conjugated estrogen vs. Stillbestrol: A point of view. PMID- 4301297 TI - [Behavior of total-body and regional radioactivity in patients subjected to intra lymphatic radiotherapy]. PMID- 4301298 TI - [Influence of the stimulation of the trigeminal nerves on the vago-vagal reflex]. PMID- 4301299 TI - [Eye exploratory movements]. PMID- 4301300 TI - [The differential diagnosis of growth retardation in childhood]. PMID- 4301301 TI - [Salivary duct carcinoma. A group of salivary gland tumors analogous to mammary duct carcinoma]. PMID- 4301302 TI - Reversible inhibition of the reproduction of DNA viruses by glycosides of 2 phenethyl alcohol and related compounds. PMID- 4301303 TI - The angiotensin I converting enzyme activity of subtilisin BPN' (Nagarse), a crystalline enzyme from Bacillus subtilis. PMID- 4301304 TI - [Current incidence of herpetic encephalitis in adults: on a personal series of 8 cases confirmed by electron microscopy]. PMID- 4301305 TI - [Determination of the effect in vitro of various antiseptics on the equine rhinopneumonitis virus]. PMID- 4301306 TI - [Presence of cytomegalic virus in some rodents of Equatorial Africa]. PMID- 4301307 TI - A new method of phallography (PhG). PMID- 4301308 TI - Cystosarcoma phylloides. PMID- 4301309 TI - [Studies on Japanese encephalitis virus in tissue culture. Growth experiments with Japanese encephalitis virus in PK and PS cell cultures observed by the fluorescent antibody method and the plaque assay technique]. PMID- 4301310 TI - Effect of poxvirus infection on host cell deoxyribonucleic acid synthesis. AB - Deoxyribonucleic acid (DNA) synthesis was studied in poxvirus-infected cells by measuring (14)C-thymidine incorporation into viral and host cell DNA. A complete separation of the two species of DNA was achieved by combining the previously used "Dounce method" with a separation method based on different reannealing properties of viral and vertebrate DNA. Shortly after infection of HeLa cells with poxviruses, a burst of viral DNA synthesis occurred in the cytoplasm, but a rapid inhibition of host-cell DNA synthesis in the nucleus was observed. This inhibition of cellular DNA synthesis was also found if an accumulation of viral DNA was prevented. At high multiplicites, ultraviolet-irradiated virus inhibited host-cell DNA synthesis to the same extent as fully infectious poxvirus. Under the same conditions, heating at 60 C for 15 min caused a decrease in the ability of cowpox virus to inhibit host-cell DNA synthesis, but did not produce the same effect on vaccinia virus strain WR. PMID- 4301311 TI - Rescue of temperature-sensitive poliovirus. AB - A temperature-sensitive strain of type 1 poliovirus, LSc, was functionally rescued when infected cells were incubated at 40 C in the presence of Mahoney, a temperature-resistant strain of type 1 poliovirus. The rescue value was 9% of the mutant yield obtained under permissive conditions. Rescued virus underwent replication, because the progeny of (32)P-labeled LSc were not radiosensitive. Serum inactivation studies with Mahoney specific antiserum indicated that a small amount of phenotypic mixing occurred among the rescued particles. The temperature sensitive event occurred between 2 and 4 hr postinfection in the developmental cycle of LSc. Neither viral polymerase activity nor virus-induced ribonucleic acid could be demonstrated in infected cells between 2 and 4 hr after infection at 40 C with the temperature-sensitive mutant. PMID- 4301312 TI - Biosynthesis of host and viral deoxyribonucleic acid during hyperplastic fowlpox infection in vivo. AB - The synthesis of deoxyribonucleic acid (DNA) during in vivo infection of chick epithelium with fowlpox virus was examined by incorporation of tritiated thymidine into the acid-insoluble fraction. The proportion of precursor incorporated into host and viral DNA at various times after infection was determined by chromatography on columns of methylated albumin-kieselguhr. The first 60-hr period of infection was characterized by the synthesis of predominantly host DNA, the rate of production of which increased markedly over the control between 36 and 48 hr postinoculation (PI). Although the replication of viral DNA began between 12 and 24 hr PI, the rate of synthesis was very low during the first 60 hr. In contrast, an abrupt increase in the rate of viral DNA synthesis occurred between 60 and 72 hr PI, concomitantly with a sharp decline of host DNA synthesis. Subsequently, between 72 and 96 hr, the ratio of synthesis of viral DNA to host DNA progressively increased to a maximum of greater than 2:1. The temporal relationship of this biphasic pattern of host and viral DNA synthesis to hyperplasia and viral replication is discussed. PMID- 4301314 TI - Specific role of each human leukocyte type in viral infections. II. Phytohemagglutinin-treated lymphocytes as host cells for vesicular stomatitis virus replication in vitro. AB - The mitogenic agent, phytohemagglutinin (PHA), added to human mixed leukocyte cultures and to lymphocyte cultures converted small lymphocytes into lymphoblasts and increased lymphocyte susceptibility to vesicular stomatitis virus (VSV). Maximum virus yields were 30- to 1,000-fold higher in PHA-treated than in control cultures. VSV replicated to peak titers before lymphocytes were morphologically transformed by PHA, and virus titers fell as lymphoblast destruction began. PHA neither induced significant VSV replication in polymorphonuclear leukocyte cultures, nor increased the large virus yields in monocyte cultures. The treatment of PHA with heat, digestive enzymes, rabbit anti-PHA serum and serial dilutions failed to dissociate that portion of the PHA extract responsible for the conversion of lymphocytes into virus-susceptible cells from those components responsible for leukoagglutination or lymphocyte transformation. PMID- 4301313 TI - Role of adenovirus structural proteins in the cessation of host-cell biosynthetic functions. AB - Two of the adenovirus capsid proteins, the fiber and the hexon, complexed with either KB cell or type 5 adenovirus deoxyribonucleic acid (DNA). Maximal binding occurred at 0.01 m NaCl; increasing the ionic strength of the reaction mixture to 0.2 m NaCl resulted in a decrease in the association of either antigen to DNA. Variations of pH between 6.3 and 8.4 did not affect the binding of fiber antigen to DNA. Below pH 7.5, however, there was a small decrease in the ability of the hexon to bind nucleic acid. The association between the adenovirus structural proteins and DNA was reversible and was independent of whether the DNA was native or denatured. The fiber or hexon protein inhibited the DNA-dependent ribonucleic acid (RNA) polymerase and the DNA polymerase from KB cells. On a weight basis, the fiber protein inhibited enzymatic activity to a greater extent than the hexon. Increasing the template DNA concentration decreased this inhibition. The inhibition of the DNA-dependent RNA polymerase activity by either antigen could be reversed by increasing the ionic strength of the reaction mixture. After infection of KB cells with type 5 adenovirus, the levels of DNA and RNA polymerases remained unchanged for 15 to 20 hr. Thereafter, the specific activity of both enzymes decreased. By 30 hr postinfection, the polymerase activities were only about 30% of the enzyme activities in uninfected cells. PMID- 4301315 TI - Hybrid of monkey and human adenoviruses. AB - Following joint replication of monkey SA7 adenovirus (C8 strain) and human adenovirus type 2 in green monkey kidney tissue culture, a virus possessing the properties of a hybrid was obtained. It was designated Ad2C8. Ad2C8 preparations contained two types of viral particles: human adenovirus type 2, and hybrid particles. The hybrid virions multiplied in green monkey kidney cells in the presence of human adenovirus types 1, 2, and 3, but not 3 and 7, and acquired the capsid of the helper adenovirus. The hybrid can serve as a helper for human adenoviruses. It can apparently induce T antigen of the C8 virus but, in contrast to the latter, does not induce tumors in hamsters. PMID- 4301316 TI - Electron microscopy of herpes simplex virus. I. Entry. AB - Although capsids of herpes simplex virus were encountered within phagocytic vesicles, they were more commonly observed free within the cytoplasm. Stages in the release of virus from vesicles were not seen. There appeared to be five distinct steps in the process whereby the virus initiates infection: attachment, digestion of the viral envelope, digestion of the cell wall, passage of the capsid directly into the cytoplasm, and digestion of the capsid with release of the core. Antibody probably interferes with the first two stages. PMID- 4301318 TI - Replication of defective simian virus 40 and a monkey cell-adapting component in human kidney cells. PMID- 4301319 TI - Unilaateral proptosis secondary to intracerebral glioblastoma. PMID- 4301317 TI - Electron microscopy of herpes simplex virus. II. Sequence of development. AB - Examination of infected cells at sequential intervals after infection revealed that the first viral forms to appear were capsids enclosing cores of low density. Not until the 6th hr were dense cores encountered, and at approximately the same time enveloped virus was seen. Envelopment occurred most frequently in close proximity to the nuclear surface, although the process was also encountered within the nuclear matrix and in the cytoplasm. There was often extensive proliferation of the nuclear membrane. Envelopment of the virus by budding from the cell surface was not observed. It was concluded that enveloped virus consitutes the infectious particle and that the unenveloped capsid is unstable outside the cell. Nevertheless, it is likely that capsids enclosing infectious nucleic acid can pass directly from one cell to another after fusion has taken place. PMID- 4301320 TI - Cytosarcoma phyllodes mammae. PMID- 4301321 TI - [Mixed tumors and their malignant degeneration]. PMID- 4301322 TI - [Effect of psychotropic drugs on brain NAD metabolism]. PMID- 4301323 TI - [The dream andthe body. Contribution to psychosomatic theory]. PMID- 4301324 TI - [Arteriography in spinal cord compression]. PMID- 4301325 TI - [Syndrome of elective inexcitability of afferent fibers of fusorial origin]. PMID- 4301326 TI - [Clinical and physiopathological study of contractures]. PMID- 4301327 TI - [S-100 protein and human cerebral tumors]. PMID- 4301328 TI - Studies on the fractionation of urinary 11-deoxy-17-ketosteroids with gas-liquid chromatography, with special reference to the evaluation of determination procedures and results in aged subjects and in several pathological conditions. PMID- 4301329 TI - The inactivation of foot-and mouth disease virus by chemicals and disinfectants. PMID- 4301330 TI - [On various results of the study of the oncogenicity of viruses]. PMID- 4301331 TI - [Isolation of thermoresistant mutants of herpes simplex virus by the plaque method]. PMID- 4301332 TI - [Cytomorphologic study of experimental herpes in relation to the serologic types of the etiologic agent]. PMID- 4301333 TI - [The effect of infection with virus MHV-3 on the content of nitrogen, phosphorus, fat and dry substance of various organs of mice]. PMID- 4301334 TI - [Complement fixing antigen in mammalian tissue culture cells infected with the Rous chicken sarcoma virus]. PMID- 4301335 TI - [Study of the genetic characteristics of the foot and mouth disease virus in the process of attenuation]. PMID- 4301336 TI - [Immunoluminescent analysis of varuses with the contrast of non-specific luminescence]. PMID- 4301337 TI - [Early results (initial effects) of the treatment with mogadan in propulsive petit mal epilepsy]. PMID- 4301338 TI - [Contribution to the problem of the occurrence of an RNA in the membranes of the endoplasmic reticulum]. PMID- 4301339 TI - Development of pediatric cardiology. PMID- 4301340 TI - A controlled study of all-night sleep in overactive imbecile children. PMID- 4301341 TI - Distribution of ACTH in the hypophysis of Necturus. PMID- 4301342 TI - Effect of adenine and nicotinamide on amino acid incorporation of cell-free systems inhibited by diphtheria toxin and NAD. PMID- 4301343 TI - [On the pathologic anatomy of malignant synoviomas]. PMID- 4301344 TI - [On glomic tumors and glomangiomas of the stomach]. PMID- 4301345 TI - [Histochemical study of liver enzymes in chronic hepatitis and cirrhosis of the liver]. PMID- 4301346 TI - [Adenomas of the trachea]. PMID- 4301347 TI - Statistical analysis of membrane potential fluctuations. Relation with presynaptic spike train. AB - In a study of integration at the single neuron level, the relationships between the postsynaptic membrane potential and the presynaptic spike train were analyzed. Fluctuations in membrane potential of neurons in the visceral ganglion of Aplysia were measured and described by histograms. The histogram estimates the probability density function of the membrane potential. Comparisons were made among histograms when there was no synaptic input, and when there was a single input in which variations were made in the PSP (postsynaptic potential) sign, i.e. excitatory or inhibitory, and arrival statistics, e.g. slow or fast, regular, Poisson-like, or patterned. This was examined in cells where the membrane potential was constant and in cells in which there was spontaneous pacemaker activity. The form of the histogram depended on whether the neuron was spontaneously quiescent or a pacemaker, or whether it received presynaptic input and, if it did, on the sign and temporal characteristics of such input. From such histograms the mean firing rate of output spike trains can be predicted; additional information of a temporal nature is required, however, to predict features of the interval structure of the output train. Suggestions are made concerning the way the nervous system might utilize the information summarized in the membrane potential histogram. PMID- 4301348 TI - How can the voluntary bodies best assist in the global attack on tuberculosis. A panel discussion held in Paris on September 20th and 21st 1962. PMID- 4301349 TI - [Diagnosis of brain metastasis from a smear of cerebrospinal fluid]. PMID- 4301350 TI - Two unusual cases of segmental colitis. Fibroplastic linitis of the colon due to gastric carcinoma and regional colitis with retroperitoneal fibrosis. PMID- 4301351 TI - [On the problem of the treatment of West syndrome]. PMID- 4301352 TI - Effects of ACTH and cortisol on water movement in isolated intestine of the eel, Anguilla japonica. PMID- 4301353 TI - Post menopausal bleeding related to estrogen therapy. An increasing problem. PMID- 4301354 TI - Effect of the number of primed cells on the production of IgM and IgG antibodies in an adoptive secondary response. PMID- 4301355 TI - Effect of reticuloendothelial system stimulation on resistance to Rous sarcoma virus infection in chicks. PMID- 4301356 TI - Mast cells in the nervous system. PMID- 4301357 TI - Cutaneous and penile bovine fibropapillomatosis and its control. PMID- 4301358 TI - Interferon response of human leukocytes during intrauterine and postnatal life. PMID- 4301359 TI - [Suicide occurring among mental patients after departure from the psychiatric hospital and its relation to depressive states occurring during the same period. Apropos of these cases]. PMID- 4301360 TI - Demyelinating disease in a woman from tropical South America with features of multiple sclerosis and neuromyelitis optica. Clinical, protein chemistry and pathological findings. PMID- 4301361 TI - Experimental diphtheritic neuropathy. A pathological and electrophysiological study. PMID- 4301362 TI - The pathology of the muscle spindle. A study of biopsy material in various muscular and neuromuscular diseases. PMID- 4301363 TI - Cytomegaloviremia following congenital infection. PMID- 4301365 TI - [Case of primary hepatoma secondary to acute viral hepatitis]. PMID- 4301364 TI - Screening of newborn infants for cytomegalovirus infection. PMID- 4301366 TI - [Inconsistent correlation between sporulation and heat-resistance of Cl. perfringens]. PMID- 4301367 TI - [Bronchial cancer and pleural mesothelioma in asbestosis (2 further cases)]. PMID- 4301368 TI - [General medical measures in neoplastic diseases and their complications]. PMID- 4301369 TI - Impaired secretion of epinephrine in response to insulin among hypophysectomized dogs. PMID- 4301370 TI - The normal and abnormal pancreatic scan. PMID- 4301371 TI - Radiologic case presentation no. 4. PMID- 4301372 TI - Epidermolysis bullosa and amyloidosis: a case report. PMID- 4301373 TI - ACTH drip in prednisone resistant pemphigus. PMID- 4301375 TI - [Cytochrome oxidase activity of cortex tissue during experimental traumatic shock]. PMID- 4301374 TI - [Serotonin effect on the activity of nucleosidetriphosphate hydrolases of rabbit brain and liver]. PMID- 4301376 TI - [Glomus tumor of the stomach]. PMID- 4301377 TI - [Osteosynthesis in pathological fractures of the femur and humerus]. PMID- 4301378 TI - [The effect of protein synthesis inhibitor on Krebs II cells infected with EMC virus]. PMID- 4301379 TI - [On the histochemical features of salivary gland tumors]. PMID- 4301380 TI - [Clinico-electromyographic studies in scleroderma and dermatomyositis]. PMID- 4301381 TI - Rifampin and ethambutol in the retreatment of advanced pulmonary tuberculosis. PMID- 4301382 TI - A continuing study of patients with "open negative" status at Battey State Hospital. PMID- 4301383 TI - [Distribution of the range of natural sensitivity to antitubercular preparations in cultures of strains of mycobacterum BCG]. PMID- 4301384 TI - Long-term dwarfing effects of corticosteroid treatment for childhood nephrosis. PMID- 4301385 TI - [Secondary carcinoma in primary non-malignant mixed tumors of the salivary glands]. PMID- 4301386 TI - [Photoreduction of pyridine nucleotide by chromatophores from Rhodopseudomonas capsulata with molecular hydrogen]. PMID- 4301387 TI - Citramalate lyase of Clostridium tetanomorphum. PMID- 4301388 TI - Vascular reactivity studies in hypertension. PMID- 4301389 TI - The effects of alpha-adrenergic receptor blockade and sympathetic denervation of the pressor action of angiotensin in man. PMID- 4301390 TI - Interactions between angiotensin, noradrenaline and serotonin on the peripheral blood vessels in man. PMID- 4301391 TI - Effect of hydroxyurea on ribonucleotide reductase. PMID- 4301392 TI - Ferredoxin dependent synthesis of alpha-ketoglutarate and pyruvate by extracts of the green photosynthetis bacterium Chloropseudoonas ethylicum. PMID- 4301393 TI - Effects of the oxidation state, ligands, detergents and aging on the conformation of cytochrome oxidase. PMID- 4301394 TI - Effect of 5-fluorouracil and 5-bromo-2'-deoxyuridine on the induction of thymidine kinase in polyoma virus-infected mouse embryo cells. PMID- 4301395 TI - Disaccharidase activity of renal tissue. PMID- 4301396 TI - Rapid diagnosis of herpesvirus hominis infections in superficial lesions by immunofluorescent antibody technics. AB - Scrapings from lesions of the skin and mucous membranes of 14 patients suspected of suffering from suspected Herpesvirus hominis infections were examined by both fluorescent antibody and routine isolation techniques. There was complete correlation between results by both methods in all 14 cases, 12 being positive. No positive fluorescence was obtained from scrapings of seven control patients with a variety of skin diseases. Thirteen patients with corneal lesions were similarly investigated. Of the 10 scrapings which showed positive fluorescence, nine were confirmed by virus isolation. It is suggested that as more antiviral agents become available the application of a fluorescent antibody technique for testing virus sensitivity in tissue culture could become a practical method. PMID- 4301397 TI - Iliacus haematoma syndrome as a complication of anticoagulant therapy. PMID- 4301398 TI - [Management of dermatitis herpetiformis]. PMID- 4301399 TI - [Prerequisites for neurovirological and neurotoxicological tests in animal experiment]. PMID- 4301400 TI - [Therapy of toxic colon dilation]. PMID- 4301401 TI - [Comparative diagnostic investigations in fetuses and foals with rhinopneumonitis virus infection (equine virus abortion)]. PMID- 4301402 TI - Determination of 3',5'-adenosine monophosphate with a method based on a radioactive phosphate exchange reaction. PMID- 4301403 TI - Studies on the respiratory chain-linked reduced nicotinamide adenine dinucleotide dehydrogenase. XV. Interactions of piericidin with the mitochondrial respiratory chain. PMID- 4301404 TI - Isolation and characterization of beta-methylene-l-(+)-norvaline from Lactarius helvus. PMID- 4301405 TI - Studies on heart phosphofructokinase. Thiol groups and their relationship to activity. PMID- 4301406 TI - The enzymatic carboxylation of phosphoenolpyruvate. IV. The binding of manganese and substrates by phosphoenolpyruvate carbosy-kinase and phosphoenolypyruvate carboxylase. PMID- 4301407 TI - Cytochrome P-450 involvement in the oxidation of n-octane b cell-free extracts of Corynebacterium sp. strain 7E1C. PMID- 4301408 TI - Characteristics of microbial diphosphopyridine nucleotidases containing exceptionally large amounts of polysaccharides. PMID- 4301409 TI - Diagnostic value of liver function tests and Entamoeba histolytica antibody studies in East Africans. AB - Liver function tests and Entamoeba histolytica (E.H.) antibody titres have been studied in a variety of tropical and liver diseases. Patients with hepatic amoebiasis had a raised E.H. antibody titre and tended to have a low pseudocholinesterase activity. In two cases of amoebic liver abscess, which were treated by aspiration and emetine, there was a remarkable drop in the E.H. antibody titre. In a number of other hepatic and tropical conditions the E.H. antibody titre was not significantly raised and the liver function tests were typical of the various conditions studied. PMID- 4301410 TI - Rgulation of intestinal alkaline phosphatase levels in the rat. Role of the adrenal cortex. AB - Bilateral adrenalectomy produces a reduction in the alkaline phosphatase concentration in rat intestine, which is not prevented by the administration of saline, but is prevented by the administration of cortisone. The administration of A.C.T.H. to normal rats leads to a rise in intestinal alkaline phosphatase levels associated with a small increase in the weight of the adrenals, while the administration of hydrocortisone produces large increases in the enzyme, even with doses which cause significant hypoplasia of the adrenal glands. The significance of these findings in relation to mechanisms of fat absorption and the treatment of steatorrhoea is discussed. PMID- 4301411 TI - Serologic relationship o a simian Herpes virus (SA8) and Herpes simplex virus: heterogeneity in the degree of reciprocal cross-reactivity shown by rabbit 7S and 19S antibodies. PMID- 4301412 TI - Granular cell myoblastoma of the bladder: report of a case. PMID- 4301413 TI - Carcinoma of the urachus: Report of two cases and review of the literature. PMID- 4301414 TI - Enlarged jugular foramen. PMID- 4301415 TI - [Diabetic neuropathy of the eye]. PMID- 4301416 TI - [Changes in the production of adrenal cortex hormones in old age]. PMID- 4301417 TI - [On the possible peculiarities of hypoglycemic disease in women]. PMID- 4301418 TI - [The differential aspect of the diencephalic syndrome of the Itsenko-Cushing disease type]. PMID- 4301419 TI - Effect of connective tissue and collagen on platelet lactate production: role of acid mucopolysaccharides. PMID- 4301420 TI - Studies on the physico-chemical inactivation of rabbit inerferons. PMID- 4301422 TI - Attempts to infect rhesus monkeys with human type 4 adenovirus. PMID- 4301421 TI - Histological effects of procedural and environmental factors on isolated rat heart preparations. PMID- 4301424 TI - The mammary tumor virus in organs of mice: normal distribution and postinoculation localization. PMID- 4301423 TI - Virus carrier cells and virus-free cells in fetal rubella. PMID- 4301425 TI - Kinetics of the development of factors responsible for inerferon-induced resistance. PMID- 4301426 TI - Antithyroid effects of 3-amino-1,2,4-triazole. PMID- 4301427 TI - Yaba tumor virus. I. Studies on pathogenesis and immunity. PMID- 4301428 TI - Radiation responeses of embryonal and SV40 transformed hamster cells in culture. PMID- 4301429 TI - Method for increasing the diagnostic capacity of the complement fixation test in some resporatory virus infections. PMID- 4301430 TI - Increased susceptibility to murine hepatitis virus infection by treatment with iron salts. PMID- 4301431 TI - The spectrum of rhinovirus inhibitor by 2-(alpha-hydroxybenzyl)-benzimidazole and D-(-)-2-(alpha-hydroxybenzyl)-benzimidazole HC1. PMID- 4301432 TI - Recovery of virus from bulls affected with foot-and-mouth disease. PMID- 4301433 TI - [Long-term results of Billroth 1 resections of the stomach in cancer]. PMID- 4301434 TI - [Cylindromas of the nose and associated sinuses (Morphological study)]. PMID- 4301435 TI - [Autologic reaction of serum precipitation in mice of the C3HA line with extracts of normal tissue and hepatomas]. PMID- 4301436 TI - [Antitumor activity of various derivatives of nitrosourea]. PMID- 4301437 TI - [A strain of guinea pig tumor cells]. PMID- 4301438 TI - [Various types of cell transformation in vitro by viruses]. PMID- 4301439 TI - [A study of the correlation between the production of interferon by the whole organism and its leukocytes]. PMID- 4301440 TI - [Complement fixing antibodies to various viruses inducing acute respiratory diseases in children of various ages]. PMID- 4301441 TI - [Setting up the neutralization reaction for group B arboviruses in tissue culture]. PMID- 4301442 TI - [Study of the effect of the toxins of intestinal bacteria on various enteroviruses]. PMID- 4301443 TI - [Conditions for the detection of the transforming activity of Rous virus in chick embryo tissue cultures]. PMID- 4301444 TI - [Virologic studies in amicrobial urethritis]. PMID- 4301446 TI - [Covered perforated amebic abscess of the liver]. PMID- 4301445 TI - [Activation of a filterable agent in human embryo tissue culture infected with polyoma virus]. PMID- 4301447 TI - [On the intraepidermal metastasis]. PMID- 4301448 TI - Clearing-factor lipase in adipose tissue. A possible role of adenosine 3',5' (cyclic)-monophosphate in the regulation of its activity. AB - 1. The rise in clearing-factor lipase activity that occurs when epididymal fat bodies from starved rats are incubated in appropriate media in vitro is inhibited in the presence of 6-N-2'-O-dibutyryl-3',5'-(cyclic)-AMP (1mm). 2. Inhibition occurs at a concentration of glucose in the incubation medium of 1.3mg./ml. or less, but not at a glucose concentration of 2.4mg./ml., unless caffeine (1mm), an inhibitor of 3',5'-(cyclic)-nucleotide phosphodiesterase, is also present. Caffeine (5mm) alone inhibits the rise in clearing-factor lipase activity at a glucose concentration of 2.4mg./ml. of medium. 3. The concentration of free fatty acids in the epididymal fat bodies normally falls during incubations in vitro as the rise in clearing-factor lipase activity occurs. In the presence of 1mm-6-N-2' O-dibutyryl-3',5'-(cyclic)-AMP, however, either the tissue free fatty acid concentration is increased or it does not fall to the same extent. The concentration of glucose in the incubation medium is important in determining the direction and extent of the changes in tissue free fatty acid concentration that occur in the presence of 6-N-2'-O-dibutyryl-3',5'-(cyclic)-AMP. 4. Free fatty acid concentrations in epididymal fat bodies in vivo rise as the clearing-factor lipase activity of the tissue falls during starvation. 5. The possibility that the concentration of 3',5'-(cyclic)-AMP in adipose tissue may regulate clearing factor lipase activity, and that the regulation may occur through effects of the nucleotide on tissue free fatty acid concentrations, is discussed. PMID- 4301449 TI - Changes in the concentrations of some phosphorylated intermediates and stimulation of glycolysis in liver slices. AB - 1. The concentrations of some phosphorylated glycolytic intermediates and of NADH were measured in glycolysing rat liver slices. 2. In anaerobically incubated liver slices the concentration of hexose monophosphates decreases during the first 20min. of incubation, whereas the concentrations of fructose diphosphate and triose phosphates increase progressively. 3. In liver slices from fed rats, previously exposed to oxygen, the stimulated anaerobic glycolysis is accompanied by an increase in the concentration of hexose monophosphates; fructose diphosphate and triose phosphates maintain the concentrations reached at the end of the aerobic preincubation. 4. The same pattern in the concentration of glycolytic phosphorylated intermediates is seen under all conditions where aerobic preincubation brings about a stimulation of anaerobic glycolysis. A similar pattern is also found in liver slices from fed rats incubated anaerobically in the presence of fructose; these slices display a high glycolytic activity, which is not further affected by previous aerobic incubation. 5. The concentration of NADH decreases in liver slices during exposure to oxygen; during the subsequent anaerobic glycolysis the concentration increases but is always lower in preincubated than in non-preincubated liver slices. 6. The results of the present experiments suggest that the limiting step mainly affected by the preliminary exposure to oxygen might be at the level of the utilization of triose phosphates. PMID- 4301450 TI - The displacement of calcium ions from phospholipid monolayers by pharmacologically active and other organic bases. AB - 1. The binding of (45)Ca(2+) to a monolayer of phosphatidylinositol at the air water interface was maximal when the separation of the phospholipid head groups approximated to the diameter of a hydrated Ca(2+) ion. 2. The displacement of Ca(2+) adsorbed on monomolecular films of phosphatidylinositol by a series of drugs (both narcotic and excitatory) and other organic bases was related to the ability of the bases to penetrate into the film. 3. With films of phosphatidylinositol at constant area, and at an initial surface pressure of 10dynes/cm., the displacement of Ca(2+) by increasing concentrations of the local anaesthetic, tetracaine, was linearly related to the change in surface pressure (Deltapi) caused by the penetration of the drug. 4. Deltapi and the displacement of Ca(2+) showed a related fall when the initial surface pressure of the phosphatidylinositol film was increased from 4 to 40dynes/cm. both at a constant bulk tetracaine concentration and when this latter concentration was adjusted to keep it at a constant ratio to the surface density of phosphatidylinositol molecules. 5. The displacement of Ca(2+) from phosphatidylinositol films by cetyltri-methylammonium ions was directly compared with the surface concentration of the base in the film, measured by using labelled base and a surface radioactivity technique. 6. The ability of a series of straight-chain aliphatic amines to displace Ca(2+) from phosphatidylinositol films increased with the number of carbon atoms up to C(12). However, there was a marked jump in the displacing activity after hexylamine, and this could probably be correlated with the carbon chain's being of sufficient length to just reach the hydrophobic fatty acid chains of the orientated phospholipid molecules with the charges on both substances in juxtaposition. PMID- 4301451 TI - Leaf extract purification by silver nitrate-silica gel thin-layer chromatography. PMID- 4301452 TI - Maintenance of axonal conduction and membrane permeability in presence of extensive phospholipid splitting. PMID- 4301453 TI - Induction of collagenolytic and proteolytic activities by anti-inflammatory drugs in the skin and fibroblast. PMID- 4301454 TI - Regional and subcellular distribution of adenyl cyclase and 3',5'-cyclic nucleotide phosphodiesterase in brain and pineal gland. PMID- 4301455 TI - Properties of hemoglobin M. Unequivalent nature of the alpha and beta subunits in the hemoglobin molecule. PMID- 4301456 TI - Isolation and amino acid composition of insoluble elastin. Bovine foetal and adult aorta and ligamentum nuchae. PMID- 4301457 TI - Aniridia and wilms's tumour (nephroblastoma). PMID- 4301459 TI - Effects of divalent cations on K+ transport in rat liver and Morris hepatoma 5123tc. PMID- 4301460 TI - Some ultrastructural features of Yoshida ascites hepatoma. PMID- 4301458 TI - Characterization of four transplantable mammotropic pituitary tumor variants in the rat. PMID- 4301461 TI - Comparative incorporation of tritiated thymidine and cytidine into the mitochondrial and nuclear DNA and RNA of two transplantable hepatomas (3924a and h-35tc2) and host livers. PMID- 4301462 TI - Micro-determination of human plasma renin activity with the addition of homologous substrate. PMID- 4301463 TI - Cystathioninuria in hepatoblastoma. PMID- 4301464 TI - Interference of pyrophosphate in the determination of orthophosphate. PMID- 4301465 TI - Abnormal urinary excretion of p-hydroxyphenyllactic acid in Wilms' tumor. PMID- 4301466 TI - [Alkaline phosphatase and acid phosphatase of the saliva and serum in diseases of the periodontium]. PMID- 4301467 TI - [Chromolymphography of the upper extremities]. PMID- 4301468 TI - X-radiation from positive ion beams incident on insulator targets. PMID- 4301469 TI - Enzyme histochemistry of the choroid plexus in rat and squirrel monkey. PMID- 4301470 TI - Innervation of the vesical detrusor muscle by the ganglia of the pelvic plexus. PMID- 4301471 TI - Human urinary polypeptides with parathyroid-like activity. PMID- 4301472 TI - Stimulation and inhibition of ACTH release in patients with pituitary disease. PMID- 4301473 TI - Serum renin activity during normal pregnancy: effect of alterations of posture and sodium intake. PMID- 4301474 TI - Effect of iodized oil on serum TSH determined by immunoassay in endemic goiter subjects. PMID- 4301475 TI - Measurement of plasma angiotensin II and correlation with renin activity. PMID- 4301477 TI - Automated enzymatic fluorometric method for the determination of pyruvic and lactic acids in blood. AB - A simple automated fluorometric method for the estimation of lactate and pyruvate is described. Analyses can be performed at 60/hour and can conveniently determine pyruvate and lactate in the ranges 0-5 mg. and 0-30 mg/100 ml. The methods give a high degree of analytical precision and good yields from recovery experiments. PMID- 4301476 TI - Thyroid carcinoma and Cushing's syndrome. A report of two cases with a review of the common features of the "non-endocrine" tumours associated with Cushing's syndrome. AB - Two cases of thyroid carcinoma and Cushing's syndrome are reported. Nine other previously published cases of this association are reviewed: in one the thyroid tumour was described as medullary, in two as papillary, and in the other six as anaplastic, undifferentiated, atypical, or solid carcinoma. Both of our own cases were medullary carcinomas of the thyroid, and on reviewing the histology of five of the other cases all proved to be medullary carcinoma with identifiable amyloid in the stroma. A consideration of the temporal relationships of the development of the carcinoma and of Cushing's syndrome suggested that in the two cases with papillary carcinoma these conditions could have been unrelated, but that in eight of the nine cases with medullary carcinoma there was evidence that thyroid carcinoma was present at the time of diagnosis of Cushing's syndrome. The other main groups of the so-called ;non-endocrine' tumours associated with Cushing's syndrome are briefly reviewed, and evidence that a surprising number of these cases are related to carcinoid tumours is put forward. Medullary carcinoma of the thyroid is also probably related to this group of tumours. It is suggested that the great majority of the tumours associated with Cushing's syndrome are derived from cells of foregut origin which are endocrine in nature. In neoplasms derived from these cells the polypeptide hormone may well be imperfectly formed, and possess an amino-acid sequence in common with ACTH or other biologically active polypeptides. PMID- 4301479 TI - [Zollinger-Ellison syndrome and pancreas cystadenoma]. PMID- 4301478 TI - Calfhood viral diseases and early vaccination studies. PMID- 4301480 TI - [Histochemical changes of NAD-diaphorase and glucose-6-phosphate dehydrogenase of various organs in rat after whole body x-irradiation]. PMID- 4301481 TI - Mental retardation and dermatoglyphics in a family with the oral-facial-digital syndrome. PMID- 4301482 TI - [Choroid tumor of a special glomic type]. PMID- 4301483 TI - The cation-sensitive phosphatases of the leucocyte cell membrane. PMID- 4301484 TI - Organizational difference of cell surface "hematoside" in normal and virally transformed cells. PMID- 4301485 TI - Interaction of homologous transfer RNA with yeast aminoacyl-RNA synthetases. PMID- 4301487 TI - Selective desensitization of the allosteric glutamic dehydrogenase from Blastocladiella by Hg. PMID- 4301486 TI - Glutamate dehydrogenase in nuclear and mitochondrial fractions of rat liver. PMID- 4301488 TI - Ornithine activating enzyme from Bacillus brevis. PMID- 4301490 TI - Complexes of chicken heart lactic dehydrogenase with coenzymes and substrates. PMID- 4301489 TI - The role of calcium (Ca++) in TSH and dibutyryl 3'5' cyclic AMP stimulation of thyroid glucose oxidation and phospholipid synthesis. PMID- 4301491 TI - [Persistance of the adrenocortical circadian rhythm in the course of submaximal corticoid inhibition obtained with a preparation with delayed absorption]. PMID- 4301492 TI - [The nephrogram under the effect of angiotensin]. PMID- 4301493 TI - [Malignity of the mixed tumors]. PMID- 4301494 TI - Chemodectoma of lung. AB - The histological and histochemical features of a primary chemodectoma of lung are described and compared with previously reported pulmonary chemodectomata. The tumour is of interest because, although there is physiological evidence that chemoreceptors are present in the lung, they have not yet been located anatomically. PMID- 4301495 TI - Optimal concentration of nicotinamide adenine diphosphate in pyruvate assays. PMID- 4301496 TI - Histopathology of fatal adenovirus infection of the respiratory tract in young children. AB - Type 7 adenoviruses were isolated from lung tissue obtained at the necropsies on five children aged 8 to 15 months. The clinical and radiological findings were those of bronchiolitis and pneumonia. Four children had an extensive necrotizing bronchitis and bronchiolitis. The surviving bronchial epithelium, and all bronchial epithelium in the fifth case, was proliferating. There was evidence that this proliferation was a virus-induced effect and not reparative. There was virus tropism to alveolar lining cells with a pneumonia showing mononuclear cellular reaction, necrosis, and hyaline membranes. Distinctive necrotizing lesions were found in the bronchial glands of all cases. Two contrasting types of intranuclear inclusions were present in all lesions and their significance and inter-relationships are discussed. These pathological changes are specific for infections by a limited number of adenovirus serotypes. PMID- 4301497 TI - Ossification in the sternum as a means of assessing skeletal age. AB - The centres of ossification in the sternum were investigated to determine whether there was any correlation between ossification in the sternum and chronological age. But this proved to be of no value in assessing skeletal age, although it may be of use in assessing skeletal maturity for pathological or forensic purposes. PMID- 4301498 TI - Morphogenesis of testicular tumours. AB - A case is described in which death resulted from multiple trophoblastic teratomatous metastases arising, apparently, from a seminoma of the left testis. This occurrence is discussed and related to similar cases recorded in the literature. It is concluded that these cases continue to provide some evidence for the seminomatous origin of teratomas. PMID- 4301499 TI - Absorption of antibiotics during peritoneal dialysis in patients with renal failure. AB - Cloxacillin, ampicillin, cephaloridine, kanamycin, and polymyxin B were administered singly in the dialysis fluid of patients having peritoneal dialysis for chronic renal failure. Therapeutic blood levels could be attained with all the drugs by the end of 12 hours of dialysis, using a concentration in the dialysis fluid which did not produce any local toxic symptoms. Absorption rates across the peritoneum were higher for cephaloridine, ampicillin, and cloxacillin than for kanamycin and polymyxin B. The serum half-lives after termination of dialysis were in excess of 11 hours, except that for cloxacillin which had a half life of about 2.5 hours. PMID- 4301500 TI - A study in vitro of the sensitivity to antibiotics of Bacteroides fragilis. AB - During a two-year period of observation Bacteroides species were isolated from specimens of pus and vaginal swabs from 115 patients in this hospital. Thirty five representative strains proved on examination to be Bacteroides fragilis. Minimal inhibitory and minimal bactericidal concentrations of six antibiotics for these strains were determined. All strains were resistant to streptomycin, neomycin, and polymyxin, slightly sensitive to penicillin and ampicillin, and fully sensitive to tetracycline, chloramphenicol, erythromycin, and lincomycin. The minimum bactericidal concentrations of chloramphenicol, erythromycin, and lincomycin were two to four times the minimal inhibitory concentrations. Tetracycline failed to exert any consistent bactericidal effect.The treatment of patients with infections caused by B. fragilis is discussed in the light of the findings in vitro. PMID- 4301501 TI - Cytochrome oxidase activity in the gastric mucosa of patients with iron deficiency. AB - Cytochrome oxidase activity was assessed histochemically in gastric biopsies taken from 22 iron-deficient patients. Activity was strong only in parietal cells, and the total amount of activity appeared to be proportional to the number of parietal cells present in the sections. No evidence was found of diminished activity within parietal cells. PMID- 4301502 TI - [Therapeutic possibilities of isotopic lymphography in genital cancers in women]. PMID- 4301503 TI - Ovarian phospholipid composition and incorporation of [1-14C] acetate into the phospholipid fatty acids of ovaries from non-pregnant and pregnant rabbits. PMID- 4301504 TI - Mechanism of resistance to enteroviruses of some primate cells in tissue culture. AB - Two cell lines, M10-45-2 and L-41, were studied, each of which possessed specific resistance either to poliovirus or to coxsackievirus. Infection of M10-45-2 cells with poliovirus ribonucleic acid (RNA) and L-41 cells with infectious coxsackievirus RNA was accompanied by production of complete viruses in each of the resistant cell lines. During incubation of the cells with the virus to which they were resistant, the amount of infectious virus did not decrease. Treatment with glycine-HCl buffer solution (pH 2.5) of resistant M10-45-2 cells after incubation with poliovirus at 0 C did not result in recovery of infectious virus, although such release did take place after treatment of sensitive M10 cells. Infection of resistant cells with virus containing poliovirus RNA and coxsackievirus proteins resulted in production of poliovirus in M10-45-2 cells but not in L-41 cells. The resistant cells are apparently unable to adsorb the virus to which they are resistant. PMID- 4301505 TI - Destruction of L cells by Mengo virus: use of interferon to study the mechanism. AB - Interferon, when added to L cells, inhibited the synthesis of infectious Mengo viral ribonucleic acid, hemagglutinins, and infectious virus by 85 to 95%. Serum blocking antigens were also reduced by the action of interferon, but threefold excess amounts of these antigens accumulated in interferon-treated cultures above the amounts expected for the quantity of infectious virus that was produced in these cultures. Radioautographic analysis showed that 28 to 36% of the cells of an interferon-treated population synthesized viral ribonucleic acid and 36 to 47% produced viral antigens as determined by an immunofluorescence technique. Despite the reductions in synthesis of viral components, all cells in an interferon treated culture underwent cytopathic effects at the same time as cells in infected cultures which had not been treated with interferon. The results are compatible with the hypothesis that the cell destruction which results from the infection of L cells with Mengo virus is due to a protein which is coded for by the virus but is not a component of the mature virion. PMID- 4301506 TI - In vitro chick embryo cell response to strain MC29 avian leukosis virus. AB - Strain MC29 avian leukosis (myelocytomatosis) virus induced infection, elaboration of virus, and morphological alteration in chick embryo cells in vitro. Virus liberation began within 18 hr, morphological change was detectable at about 40 hr, and the cultures could be completely altered within 80 hr after infection. Altered cells were about half the volume and grew at approximately twice the rate of uninfected elements. The output of virus estimated by electron microscopy was about 140 particles per cell per hr. Deoxyribonucleic acid remained constant, but ribonucleic acid increased in both infected and control cells in adjustment to culture environment. The rates of uptake and incorporation of (3)H-uridine and the incorporation of (3)H-thymidine increased in the infected cells with onset of morphological change but were unaffected by processes of infection and virus elaboration per se. Incorporation of a (14)C-amino acid mixture was slightly greater in the infected than in control cells. The speed of continuity of infection and massive morphological alteration constitute a unique response to avian tumor viruses, and the system gives promise of singular value for detailed studies of the processes of infection and morphological change. PMID- 4301508 TI - Effects of ultraviolet irradiation on the transforming and plaque-forming capacities of simian adenovirus SA7. PMID- 4301507 TI - Herpes simplex virus-host cell relationships in organized cultures of mammalian nerve tissues. AB - Studies on the replication of herpes simplex virus in organized cultures of rat central nervous system (CNS) and peripheral nervous system (PNS) tissue demonstrated synthesis of intra- and extracellular virus, as determined by plaque assay on HEp-2 cells. Newly synthesized intracellular virus appeared 12 to 14 hr after inoculation of CNS, followed 10 hr later by the appearance of extracellular virus. In PNS cultures, where higher inputs of virus were introduced, intracellular virus appeared 6 to 8 hr after inoculation, followed by extracellular virus 12 hr later. Polykaryocyte formation was observed in CNS and PNS tissue involving neuroglial, meningeal, or Schwann cells. Neuron somas did not participate in polykaryocyte formation, but they underwent progressive morphological changes starting with increased cytoplasmic granularity followed by nucleolar distortions and disintegration, margination of nuclear chromatin, and the appearance of intranuclear inclusions. Finally, all recognizable cellular detail was lost. Immune serum globulin failed to inhibit both the progressive nature of the cytopathic effect and the synthesis of intracellular virus. These findings are discussed in relation to other in vitro systems, as well as to disease processes in man and animals. PMID- 4301509 TI - Enhancing effect of diethylaminoethyl-dextran on the focus-forming titer of a murine sarcoma virus (Harvey strain). PMID- 4301510 TI - Growth inhibition of Newcastle disease virus upon superinfection of poliovirus in the presence of guanidine. PMID- 4301511 TI - [Control of the treatment progress. Studies on uropepsin excretion during the treatment]. PMID- 4301512 TI - [Diagnosis and management of islet cell tumors]. PMID- 4301513 TI - Rose of cyclic AMP in hormone actions. PMID- 4301514 TI - Abnormalities of vitamin B12 and folic acid metabolism--their influence on the nervous system. PMID- 4301515 TI - [On the activity of enzymes at the level of nuclear pores and other structures of the prothoracic secretory cells embedded in epon]. PMID- 4301516 TI - [Comparative histological, histochemical and electron mecroscopic studies of lacrimal glands. VI. Human lacrimal gland]. PMID- 4301517 TI - [The ultrastructure of the mucoepidermoid carcinoma]. PMID- 4301518 TI - [On the morphological classification of primary pulmonary arteriopathies with pulmonary hypertension]. PMID- 4301519 TI - Effects of hypophysectomy of ACTH on the changes induced by hexadimethrine bromide. PMID- 4301520 TI - Follow-up study of 100 cases of pseudotumor cerebri. PMID- 4301521 TI - Studies on vascular permeability in peripheral nerves. 3. Permeability changes of vasa nervorum and exudation of serum albumin in INH-induced neuropathy of the rat. PMID- 4301523 TI - [Study of development of the carpal bones of children. 1. Normal developmental pattern]. PMID- 4301522 TI - Histochemical and electron microscopic observations on "onion bulb" formations in a case of hypertrophic neuritis of 25 years duration with onset in childhood. PMID- 4301524 TI - [Electrolyte metabolism in diseases of the central nervous system in children. 2. Electrolyte metabolism in focal epilepsy]. PMID- 4301525 TI - Development of strains of Cryptococcus neoformans resistant to nystatin, amphotericin B, trichomycin and polymyxin B. PMID- 4301527 TI - Attempts to map the poliovirus genome by analysis of selected recombinants. PMID- 4301526 TI - The effect of mutagens on the marker of poliovirus. PMID- 4301528 TI - Histopathology of sarcomas induced in hamsters by clones of in-vitro SV40 transformed homologous heart cells. Attempts to correlate morphologic features and degree ofoncogenic potential. PMID- 4301529 TI - [The night sleep of schizophrenics in the early stage of development. Polygraphic study by telemetry]. PMID- 4301530 TI - Growth stimulation of polyoma virus treated hamster cells in soft agar by conditioned medium. PMID- 4301531 TI - [Primary liver carcinoma in infants and childhood]. PMID- 4301533 TI - Cytotoxic, hemolytic and phospholipase contaminants of commerical neuraminidases. PMID- 4301535 TI - Evaluation of physical maturity at adolescence. PMID- 4301532 TI - Latent virus infections in primate tissues with special reference to simian viruses. PMID- 4301534 TI - Comparison of the adrenocorticotrophic activities of two synthetic polypeptides: synacthen and DW 75. AB - The adrenocorticotrophic activities of two synthetic polypeptides, Synacthen (Ciba) and DW 75 (Sandoz), were compared in two groups of patients having a variety of arthritic disorders. Compared with Synacthen, injected either intramuscularly or intravenously, intravenous DW 75 was found to have a longer duration of adrenocorticotrophic activity (measured by plasma 11 hydroxycorticosteroid levels) in both groups of patients, while intramuscularly administered DW 75 did not appear to be absorbed well. PMID- 4301536 TI - A study of the mechanism of polymyxin M inactivation. PMID- 4301537 TI - Transplacentar induction of neurogenic malignomas by 1,2-diethyl-hydrazine, azo-, and azoxy-ethane in rats. PMID- 4301538 TI - Responses of oculomotor nucleus and marginal gyrus in sleep. PMID- 4301539 TI - Carcinogenicity of tetraethyl lead. PMID- 4301540 TI - Immunofluorescent localization of beta-corticotropin in the rat pituitary. PMID- 4301541 TI - [The importance of lymphocyte glycogen for the study of chronic lymphocytic leukemias]. PMID- 4301542 TI - [Adenyl cyclase in rat brain]. PMID- 4301543 TI - [Stimulation of phosphate elimination by infusion of 3',5'-AMP (cyclic AMP) into the renal artery--a possible mechanism of action of parathyroid hormone]. PMID- 4301544 TI - [Plasticity of synaptic function in the isolated rat sympathetic ganglion]. PMID- 4301545 TI - [Influence of pyramidal tracts on the nucleus of the trigeminal nerve spinal tract in cats]. PMID- 4301546 TI - [Action of converting enzyme on synthetic substrates]. PMID- 4301547 TI - [Electron spin resonance measurements on heme-hemoglobin systems of natural blood]. PMID- 4301548 TI - [Toxic effect of oxygen under pressure on conduction and transmission in the isolated rat superior cervical ganglion]. PMID- 4301549 TI - In vitro comparative evaluation of metronidazole and other anti-amoebic drugs against Entamoeba histolytica. PMID- 4301550 TI - Anti-variola and anti-vaccinia principles from seeds of Banakadali (Ensete superbum, Cheesm, Musaceae). PMID- 4301551 TI - Transformation of mammalian cells by animal viruses. PMID- 4301552 TI - Recurrent inhibition in the giant-fibre system of the crayfish and its effect on the excitability of the escape response. PMID- 4301554 TI - Influence of vasopressin and of a crude CRF preparation on pituitary ACTH-release in posterior-lobectomized rats. PMID- 4301553 TI - Gas gangrene abscess of the brain. PMID- 4301555 TI - [Electroneuromyographic research in sympathetic and somatic pain syndromes (modifications of the H responses at the level and of the silent period at the bulbar level)]. PMID- 4301556 TI - [Neurologic complications of leukemias. Disease of the peripheral nervous system and of the meninges in a clinical case of chronic lymphatic leukemia]. PMID- 4301558 TI - The chromophore and partial structure of viomycin. PMID- 4301557 TI - [Depth dosis calculations for the 60CO eye applicators CKA 5-11 (Stallard's method)]. PMID- 4301559 TI - [Treatment of lumbosacral radiculitis with mineral-radon baths]. PMID- 4301560 TI - [Antacid effect of a magnesium trisilicate-1-hyoscyamine combination preparation (Neoplex B)--clinical and function analytical studies]. PMID- 4301561 TI - Pulmonary stenosis in patients with the Turner phenotype in the male. PMID- 4301562 TI - Effect of an exercise program on the perennially asthmatic child. PMID- 4301563 TI - Kinetic studies on the cyclic phosphodiesterase with 3' nucleotidase activity from Proteus mirabilis. PMID- 4301564 TI - Stimulation of glucose utilization and inhibition of lipolysis by polyene antibiotics in isolated adipose cells. PMID- 4301565 TI - Structural requirements for the action of steroids as inhibitors of electron transfer. PMID- 4301566 TI - Rhein: an inhibitor of mitochondrial oxidations. PMID- 4301567 TI - Spectrophotometric analysis of rat liver lactate dehydrogenase-coenzyme and coenzyme analog complexes. PMID- 4301568 TI - FDPases of the castor bean endosperm and leaf: properties and partial purification. PMID- 4301570 TI - Inactivation of yeast alcohol dehydrogenase by N-alkylmaleimides. PMID- 4301569 TI - Synthesis of indoleacetic acid from tryptophan via indolepyruvic acid in cell free extracts of pea seedlings. PMID- 4301571 TI - Studies on dextran and dextran derivatives. XIV. Metal binding properties of succinyl- and phthalyl-dextrans. PMID- 4301572 TI - Evaluation of N1-(omega-bromoacetamidoalkyl)nicotinamides as inhibitors of dehydrogenases. PMID- 4301573 TI - Arenal cells in tissue culture. I. Assay of steroid products; steroidogenic responses to peptide hormones. PMID- 4301574 TI - Glycoprotein biosynthesis: studies on the receptor specificity of the polypeptidyl: N-acetylgalactosaminyl transferase from bovine submaxillary glands. PMID- 4301575 TI - Purification and some properties of yeast citrate synthase. PMID- 4301576 TI - [The relationship between stomatitis papulosa and other diseases in man and animal]. PMID- 4301577 TI - Thyrotropin hormone deficiency with a peripheral neuropathy. PMID- 4301578 TI - Mononeuritis multiplex in lepromatous leprosy. PMID- 4301579 TI - A denaturation map of polyoma virus DNA. PMID- 4301580 TI - [Effect of synthetic angiotensin on the intestine and search for its antagonists]. PMID- 4301581 TI - [Occupational hygiene in the grading and concentration of coal]. PMID- 4301582 TI - Motor innervation of the coronary arteries of the cat. AB - 1. The effect on coronary vascular resistance of selective stimulation of the Adelta, B and sC fibre groups of the post-ganglionic cardiac sympathetic nerves was studied. The main left coronary artery was perfused at constant flow. The oxygen saturation of coronary sinus blood was measured continuously.2. Stimulation of the peripheral ends of the cut Adelta afferent fibres, normally excited by myocardial ischaemia, had no effect on coronary vascular resistance; these fibres do not evoke an axon reflex in the heart.3. Stimulation of the preganglionic B fibres that run without synapse through the stellate ganglion also had no measurable effect on coronary resistance.4. Stimulation of the post ganglionic sC fibres of the cardiac sympathetic nerves caused coronary vasodilatation which occurred earlier than, and was initially independent of the decrease in coronary sinus oxygen saturation.5. The injection of noradrenaline into the perfusion system had the same effect as stimulation of the sC fibres. In the K(+)-arrested heart, both noradrenaline and stimulation of the post ganglionic nerves elicited coronary vasodilatation without changing the oxygen saturation of coronary sinus blood.6. The intracoronary injection of acetylcholine caused coronary vasodilatation followed by an increase of coronary sinus oxygen saturation.7. Vagal stimulation caused brady cardia and a fall in coronary resistance.8. Propranolol blocked coronary vasodilatation elicited by sympathetic stimulation or noradrenaline without affecting the vasodilatation due to myocardial ischaemia or acetylcholine. Atropine blocked coronary vasodilatation evoked by acetylcholine without affecting that due to ischaemia or noradrenaline. Therefore smooth muscle of the coronary arteries has at least three different receptor sites from which vasodilatation can be elicited.9. Hypertensin caused coronary vasoconstriction.10. The presence of sympathetic cholinergic vasodilator fibres innervating the coronary arteries could not be demonstrated. PMID- 4301583 TI - Histopathology of an enzootic diarrheal disease in cattle. PMID- 4301584 TI - [Aleukemic tumor-like reticulosis in association with cytomegaly in a 3 and one half-month-old infant]. PMID- 4301585 TI - Spin-label studies of the excitable membranes of nerve and muscle. PMID- 4301586 TI - "Big insulin": a new component of plasma insulin detected by immunoassay. PMID- 4301587 TI - Conformation studies with polypeptides by rotatory dispersion and thin-film dialysis. PMID- 4301588 TI - Enzymatic joining of polynucleotides, V. A DNA-adenylate intermediate in the polynucleotide-joining reaction. PMID- 4301589 TI - Mitochondrial origin of membrane-associated heterogeneous RNA in HeLa cells. PMID- 4301590 TI - The role of Factor B in the energy transfer reactions of oxidative phosphorylation. PMID- 4301591 TI - Incorporation of oligodeoxynucleotides into DNA. PMID- 4301592 TI - Inducers of interferon and host resistance, V. In vitro studies. PMID- 4301593 TI - Rescue of infectious SV40 after fusion between dfferent SV 40-transformed cells. PMID- 4301594 TI - The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study. PMID- 4301596 TI - [Immunohistochemical studies on myosin in malignant tumors of childhood]. PMID- 4301597 TI - [Mononucleosis-like blood findings in cytomegaly]. PMID- 4301595 TI - Polypeptide cleavages in the formation of poliovirus proteins. PMID- 4301598 TI - [Continuous intra-arterial infusion of 5-fluor-2-deoxyuridine in primary and metastatic liver cancer]. PMID- 4301599 TI - [Malignant adenomatosis of the lungs]. PMID- 4301600 TI - [Glomus tumor of the hip]. PMID- 4301601 TI - [Parainfluenza viruses and their role in acute respiratory diseases]. PMID- 4301602 TI - [The effect of ACTH on arterial pressure levels and blood electrolyte ratios]. PMID- 4301603 TI - [Results of treatment of patients with pemphigus with corticosteroids and other preparations]. PMID- 4301604 TI - [The effect of antibacterial and hormone therapy on the secretory function of the stomach in pulmonary tuberculosis patients]. PMID- 4301605 TI - [Metabolis of ribonucleic acids in pathology of the sciatic nerve (experimental study)]. PMID- 4301606 TI - [Changes in motor chronaxy in diskogenic cervical radiculo-autonomic syndromes]. PMID- 4301607 TI - Treatment of intracranial gliomas and metastatic carcinomas by local application of cytostatic agents. PMID- 4301608 TI - [Diagnosis of adenovirus infection by use of fluorescent antibody technique]. PMID- 4301609 TI - Epidemiology of adenovirus-associated virus infection in a nursery population. PMID- 4301610 TI - Enteroviruses within an estuarine environment. PMID- 4301612 TI - The carrier state in pertussis. PMID- 4301611 TI - The use of rivanol treatment for removal from sera of nonspecific inhibitors of enterovirus and reovirus hemagglutination. PMID- 4301613 TI - Oral activity cycles in mild chronic schizophrenia. PMID- 4301614 TI - [On the existence of 2 kinds of smooth muscle cells in the carotid wall of bovines]. PMID- 4301615 TI - Foot-and-mouth disease. PMID- 4301616 TI - Metabolism of animal cells infected with nuclear DNA viruses. PMID- 4301617 TI - [Cytochemical aspects of the function of the thyroid gland]. PMID- 4301618 TI - [Oncogenic action of a strain of polyoma virus in Swiss white mice. (Histological study)]. PMID- 4301619 TI - [Visual and somatosensory evoked potentials during sleep in man]. PMID- 4301620 TI - Non-chromaffin paraganglioma of the kidney with distant metastases. PMID- 4301621 TI - Immunofluorescent study of the inhibitory effect of N1-N1-anhydro-bis (beta hydroxyethyl) biguanide (ABOB) on the multiplication of Sendai virus in tissue cultures. PMID- 4301622 TI - Histochemical demonstration of certain phosphomonoesterases in the Vater-Pacini receptors in cats. PMID- 4301625 TI - Cu2+ in non axial-field: a model for Cu2+ in copper enzymes. PMID- 4301623 TI - TSH-like actions of dibutyryl-cAMP on isolated bovine thyroid cells. PMID- 4301624 TI - Formate dehydrogenase from the pea seedling. PMID- 4301626 TI - Primary periodic paralysis associated with hyperkalemic and hypokalemic attacks and with hemolytic bilirubinemia. PMID- 4301628 TI - Effect of hydrocortisone and ACTH upon the bioelectric activity of spinal cord. PMID- 4301627 TI - Corticotrophin secretion capacity in multiple sclerosis. PMID- 4301629 TI - [An autoradiographic study of proliferation of the corneal epithelium infected with vaccinia virus]. PMID- 4301630 TI - The application of Triton X 100 colloid scintillation counting in biochemistry. PMID- 4301631 TI - A social and clinical study of geriatric admissions to a psychiatric hospital. PMID- 4301632 TI - [Influence of vitamin D upon growth]. PMID- 4301633 TI - [Electron microscopy of the sites of respiratory enzymes in Escherichia coli]. PMID- 4301634 TI - Protection by anoxia of the scrapie agent and some DNA and RNA viruses irradiated as dry preparations. PMID- 4301635 TI - Temperature-sensitive events in the growth of variola virus in HeLa cells. PMID- 4301636 TI - The effect of 5-bromodoxyuridine and actinomycin D on the multiplication of transmissible gastroenteritis virus. PMID- 4301637 TI - Morphological transformation of human embryonic liver cells by simian virus 40. PMID- 4301638 TI - Observations on the fine structure and replication of varicella virus in cultivated human amnion cells. PMID- 4301639 TI - The inhibition of decubitus ulceration with ACTH. PMID- 4301640 TI - Cystosarcoma phyllodes: a unique case with multiple unilateral lesions and ipsilateral axillary metastasis. PMID- 4301641 TI - [Adrenotropic effect of a natural and synthetic ACTH preparation with gelatin addition in intramuscular injections]. PMID- 4301642 TI - Electron spin resonance linewidths in met myoglobin. PMID- 4301643 TI - Relation between blood groups and resistance to infection with influenza and spome picornaviruses. PMID- 4301644 TI - Demonstration of a pseudo-cowpox virus in New Zealand. PMID- 4301645 TI - [Trophoblastic tumors. Titration of chorionic gonadotropins]. PMID- 4301646 TI - Brush border particulates of renal tissue. AB - Particulates containing a large part of the alkaline phosphatase activity of renal tissue were separated from homogenates and from ribosomal preparations by zonal centrifugation. The particles had a high content of phospholipid and cholesterol that was not removed by treatment with I percent deoxycholate. Enzymatic activities concentrated with the particles were the alkaline phosphatase, a peptidase resistant to proteolysis, glucose-6-phosphatase, inorganic pyrophos-phatase, and adenosine triphosphatase. The particles accumulated leucine with no stimulation from soluble factors and with inhibition by other amino acids; the accumulation was stimulated by adenosine triphosphate and was not inhibited by puromycin. The particles appear to be derived from the membranes of the brush borders of tubular cells. PMID- 4301647 TI - Basis for the acquisition of malignant potential by mouse cells cultivated in vitro. AB - Balb/c mouse embryo lines maintained in culture for over 200 generations under conditions that minimize cell-cell contact do not become tumorigenic. Lines cultivated under conditions where there is extensive cell contact become tumor producing within 30 generations. The tissue-culture property that correlates best with tumorigenicity is the loss of contact inhibition of cell division. PMID- 4301648 TI - Cellular aspects of the control of color changes. AAAS Symposium, 29 December 1968 Dallas, Texas. PMID- 4301649 TI - Radiobiological damage: a new class identified in barley seeds stored after irradiation. AB - A new class of radiobiological damage has been identified in irradiated barley seeds. Consisting of both physiological and genetic damage, it appears to be independent of oxygen and long-lived free radicals, and develops very slowly during storage after irradiation. Increasing the storage temperature accelerates its development. PMID- 4301650 TI - Visual cortex neurons: response to stimuli during rapid eye movements. AB - While awake, unanesthetized monkeys held their eyes stationary, a motionless or slowly moving stimulus falling on the receptive field of striate cortex neurons produced an excitatory response. When a rapid eye movement was made across the same stimulus, many of these neurons continued to give an excitatory response. But the discharge of other neurons was unchanged or was suppressed during the eye movement. PMID- 4301651 TI - [Evaluation of intraperitoneal administration of polymyxin B sulfate]. PMID- 4301652 TI - [Osteogenic sarcoma secondary to irradiation after radical mastectomy for breast carcinoma: an autopsy case]. PMID- 4301653 TI - Zoonoses in Britain: some present and potential hazards to man. Skin diseases. PMID- 4301654 TI - A short communication on another simplified micromethod for performing chromosome preparations from peripheral blood. PMID- 4301655 TI - Granular cell tumors (myoblastomas) involving the bronchus and skin. Report of a case. PMID- 4301656 TI - [Clinico-statistical contribution to the study of molar degeneration of the villus, with special reverence to "mole destruens"]. PMID- 4301657 TI - Studies on the pathogenesis of parainfluenza type 3 virus infection in hamsters. PMID- 4301659 TI - [Autoradiographic observations on the uptake of 3H-uridine in herpes-induced giant cells]. PMID- 4301658 TI - Immunological relationship between herpes simplex virus and B virus. PMID- 4301660 TI - [On the effect of neomycin and polymyxin on the multiplication of poliomyelitis virus in tissue cultures. (Short report)]. PMID- 4301661 TI - [Sleep EEG and epilepsy in cats with chronic epileptic lesions]. PMID- 4301663 TI - Energy-linked reduction of nicotinamide adenine dinucleotides in cells of Rhodospirillum rubrum. PMID- 4301662 TI - Decreased hepatic microsomal drug metabolism after the injection of a mixture containing somatotropin, corticotropin and prolactin. PMID- 4301664 TI - Reconstitution of succinic-coenzyme Q reductase and succinic oxidase activities by a highly purified, reactivated succinic dehydrogenase. PMID- 4301665 TI - [The effect of acrylamide and its hydrogenated derivative on the EPR spectrum and the growth of normal and tumorous animal tissues]. PMID- 4301666 TI - [Free radical states with localization of the unpaired electron on the sulfur atom in yeast cells]. PMID- 4301667 TI - [Experience in modeling presynaptic ingibition]. PMID- 4301668 TI - [Adsorption of chlorophyll a and b on polyacrylonitrile in powder form]. PMID- 4301669 TI - [Change in neuron ultrastructure of rain worms in the reinforcement of biosynthetic activity connected with cell excitation]. PMID- 4301670 TI - [1. On the biochemical nature of the "sulfur" signal of electron spin resonance in yeast cells]. PMID- 4301671 TI - Intermittent and pulsating exophthalmos. PMID- 4301672 TI - Changes in DNA and RNA in the rat adenohypophysis following bilateral adrenalectomy, sham adrenalectomy, and the chronic injection of cortisol. PMID- 4301673 TI - Restoration of adrenal-regeneration hypertension in corticosterone-blocked rats by ACTH. PMID- 4301675 TI - Chemotherapy in dental practice. Polypeptide antibiotics. 3. Polymyxin. PMID- 4301674 TI - [Pigmented villo-nodular synovitis of the knee]. PMID- 4301676 TI - [Observations on the changes of eosinophils and basophils in allergic dermatoses and bullous dermatoses]. PMID- 4301677 TI - [The effect of lysine-vasopressin on the concentration of 11 hydroxycorticosteroids in the plasma of endocrine-well children, as test of pituitary function]. PMID- 4301678 TI - [A contribution to A-hypervitaminosis]. PMID- 4301679 TI - The formation and reactions of hydrogen atoms in gamma-irradiated deoxyribonucleic acid gels. PMID- 4301680 TI - Coenzyme A-linked aldehyde dehydrogenase from Escherichia coli. I. Partial purification, properties, and kinetic studies of the enzyme. PMID- 4301681 TI - Identification and analysis of multiple glycine transport systems in isolated mammalian renal tubules. PMID- 4301682 TI - Oligonucleotides produced by digestion of KB cell ribosomal 5 S ribonucleic acid with specific nucleases. PMID- 4301684 TI - A study of the threonyl adenylate complex with threonyl transfer ribonucleic acid synthetase and its reaction with hydroxylamine. PMID- 4301683 TI - The divergence in reactivity of aminoacyl transfer ribonucleic acid synthetases of Escherichia coli with hydroxylamine. PMID- 4301685 TI - The role of lysyl residues in the structure and reactivity of cytochrome B5 reductase. PMID- 4301686 TI - Cytomegalic inclusion disease in the adult. AB - The distribution of infected cells in 13 necropsies on adults with cytomegalovirus disease is reported and discussed in relation to the local damage caused by the infection and predisposing factors. The distribution, with lung as the most common site, but other organs such as thyroid, liver, and colon not infrequently involved, agrees fairly well with other series. No heavy infection confined to one organ was found, and it is concluded that a truly localized infection in the adult probably does not occur. Evidence of destructive inflammatory changes attributable to the virus was scanty; a lymphocyte and plasma cell infiltrate was sometimes found, and microglial nodules were found in a case with inclusions in the brain. In one case heavy cytomegalovirus infection in the colon was associated with, and probably caused, marked colonic ulceration which led to the death of the patient. THE MAJOR PREDISPOSING FACTOR TO INFECTION IN THIS SERIES WAS CORTICOSTEROID THERAPY: eight of the 13 patients had been treated with steroids and one had Cushing's syndrome associated with a bronchial carcinoma. Three of the other four patients had a very few inclusions only. Adrenal involvement was not found in any of the steroid-treated patients but was present in two of the four patients not treated with steroids where adrenal sections were available. It is concluded that most adult patients with cytomegalovirus infection have impaired immune mechanisms, and that heavy infection may rarely lead to a clinically serious disease. PMID- 4301687 TI - Contiguous but dissimilar epithelial neoplasms of the urinary bladder. AB - An unusual tumour of the urinary bladder is described. It consists of two distinct nodules each with a quite different histological appearance, one being mucus-secreting adenocarcinoma, the other transitional cell carcinoma. Where the nodules are in contact there is little intermingling of the two histological patterns and it is suggested that the findings are probably due to the collision of two separate neoplasms. Metaplastic changes are present in the bladder mucosa adjacent to the tumour. The significance of these changes in the pathogenesis of adanocarcinoma is discussed. PMID- 4301689 TI - Routine multipurpose gas chromatographic assay for urinary corticosteroids. AB - THE USE OF A ROUTINE ASSAY FOR URINARY STEROIDS IS DESCRIBED THAT IS THOUGHT TO SATISFY THE FOLLOWING NEEDS: the measurement of low levels of 17 hydroxycorticosteroid excretion; the assessment of adrenocortical activity during prednisolone therapy; the diagnosis of the adrenogenital syndrome and the monitoring of its treatment using any available urine specimen; the very early diagnosis of pregnancy using any available urine specimen. It may also prove of value in the assessment of progesterone secretion and metabolism during pregnancy. PMID- 4301688 TI - Glucagon test for insulinoma: a chemical study in 25 cases. AB - The capillary blood glucose response to lmg of intramuscular glucagon was determined in 13 patients with insulinoma and in 33 normal controls; the insulinoma patients showed a normal initial rise, but this was followed by an abnormally large fall, reaching hypoglycaemic levels between 90 and 180 minutes in every case. In 14 insulinoma patients the response of venous blood glucose and also plasma insulin to lmg of intravenous glucagon was compared with 10 normal controls; there was an abnormally large rise of plasma insulin in 10 of the 14 patients, and in the majority the venous blood glucose was below normal throughout the test. In these 14 patients the plasma insulin response was also determined after oral and intravenous glucose, after oral leucine, and after intravenous tolbutamide, and the value of these tests in the recognition and differential diagnosis of insulinoma was compared with that of the intravenous glucagon test. PMID- 4301690 TI - [The treatment of epiletic seizures in childhood]. PMID- 4301691 TI - [Histochemical studies on the effects of arequine on motor cells of the anterior horn cells of the spinal cord]. PMID- 4301692 TI - [Studies on cutaneous nervous changes in Recklinhausen's disease]. PMID- 4301693 TI - [Cytomegalic inclusion disease. A survey]. PMID- 4301694 TI - [Cytomegalic inclusion disease in infants. Five cases, three of them with malformations, all with brain changes]. PMID- 4301695 TI - [Sleep and sleeping medicines]. PMID- 4301696 TI - [Neurectomy and anesthetic blocks of the peripheral trunk in P.V.D]. PMID- 4301697 TI - [New x-ray diagnostic examinations of the liver]. PMID- 4301698 TI - [Sex chromatin content in pre-irradiated andnonirradiated female breast carcinomas]. PMID- 4301699 TI - [Renal mechanisms in hypertension]. PMID- 4301700 TI - [The renin-angiotensin-aldosterone axis. Pathophysiological mechanisms and differential diagnostic patterns]. PMID- 4301702 TI - [On phospholipid content of muscles]. PMID- 4301703 TI - [Effect of pangamic acid (vitamin B 15) on the efficiency of experimental training]. PMID- 4301701 TI - [On the role of vitamin C in connective tissue formation]. PMID- 4301704 TI - [Qualitative changes in collagen and its role in the process of carcinogenesis]. PMID- 4301705 TI - [Study of the composition of the DNA nitrogen bases in the livers of albino rats differing in age]. PMID- 4301706 TI - [The levels of synthesis and degradation of thiaminediphosphate in subcellular particles of albino rat liver]. PMID- 4301708 TI - [A case of acute brachioscapular paralysis of Personage-Turner]. PMID- 4301707 TI - [The phosphoprotein phosphatase activity of functionally different muscles at various periods after denervation]. PMID- 4301709 TI - [Angiotensin and saluretics in nephrogenic diabetes insipidus of early infancy]. PMID- 4301711 TI - [Experimental studies on the treatment of silicosis]. PMID- 4301710 TI - [Statistical report on the grading of glioma. II. Catamnesis of glioblastoma and patient age]. PMID- 4301712 TI - Studies on the cytotoxic action of silica dusts on macrophages in vitro. PMID- 4301713 TI - Polyvalent parainfluenza CF antigen for serodiagnosis. PMID- 4301715 TI - Evidence of an infective component sensitive to ribonuclease in the brain homogenate fo mice inoculated with MM virus. PMID- 4301714 TI - [Studies on the thermal inactivation of foot-and mouth disease virus]. PMID- 4301717 TI - [Behavior of 3 strains of Entamoeba histolytica in various culture media]. PMID- 4301716 TI - Bovine enteroviruses: apparent correlation between antigenic characters and capacity to grow in the presence of small concentrations of 2-(alpha hydroxybenzyl)-benzimidazole. PMID- 4301718 TI - [Changes induced by fasting in the enzyme pattern of the rat liver and effects of chlorpromazine]. PMID- 4301719 TI - [Effect of some neuroleptic drugs and antihistaminics on the changes of the enzyme pattern induced by ischemia in the rat liver]. PMID- 4301720 TI - [Study of the changes of some enzyme activities in the liver of rats subjected to acute intoxication with allyl alcohol and of the effect of the preventive administration of chlorpromazine]. PMID- 4301722 TI - [Synthesis of fatty acids in the rat liver mitochondria. VI. Submitochondrial enzyme localization and effect of citrate]. PMID- 4301721 TI - [Biochemical research on the changes in the liver of rats treated with parenteral administration of non-physiological macromolecular substances. 3. Behavior of some hepatic enzymes after treatment with dextrans of various molecular weights, with polyvinylpyrrelidene and with "Emagel"]. PMID- 4301723 TI - [Proteinuria caused by angiotensin: electrophoretic study]. PMID- 4301724 TI - Experimental studies on bacteriocinogeneity in Cl. perfringens type A. 3. Chemical structure of isolated bacteriocines. PMID- 4301725 TI - [Adrenalitis inclusio-necroticans in the Landry-Guillain-Barre-Syndrome]. PMID- 4301726 TI - [Unusual site of synovial sarcoma (synovioma malignum)]. PMID- 4301727 TI - [Reaction of 4,5-dibromo-6-pyridazones with cysteine and the SH-groups of yeast alcohol dehydrogenase]. PMID- 4301728 TI - [Inhibition of alpha-aminoisobutyric acid transport into isolated adipose tissue by N6,02'-dibutyryladenosine 3',5'-phosphate]. PMID- 4301729 TI - Cerebral arterial spasm. 2. Experimental evaluation of mechanical and humoral factors in pathogenesis. PMID- 4301730 TI - Cerebral arterial spasm. 3. Partial purification and characterization of a spasmogenic substance in feline platelets. PMID- 4301731 TI - Effect of angiotensin on urine flow and electrolyte excretion in normal and toxemic pregnancy. PMID- 4301732 TI - [The significance of some tests for the differential diagnosis of unilateral nephropathies with arterial hypertension]. PMID- 4301733 TI - [Clinical data on the diagnostic use of angiotensin II in hypertensive disease]. PMID- 4301734 TI - [The angiotensin test in the diagnosis of renovascular hypertension]. PMID- 4301735 TI - [Comparison of renographic findings and the hypertensin test with the Kaplan method in patients with unilateral nephropathy]. PMID- 4301736 TI - [Studies on the course of spasms (paroxismal spasms) in children]. PMID- 4301737 TI - [Results of treatment and clinical and electroencephalographic evolution in infantile spasms]. PMID- 4301738 TI - [Therapy of bronchial asthma with synthetic delayed-action corticotropin]. PMID- 4301739 TI - [The effect of bethanide on aldosterone secretion in patients with renovascular hypertension]. PMID- 4301740 TI - Fibro-fatty proliferation of the median nerve. PMID- 4301741 TI - The effect of atropine and related drugs on the EEG and behaviour. PMID- 4301742 TI - [Effect of biophysical factors on the redox processes and biological oxidation. VII. Effect of ultrasonics on enzymes of the glycoltic chain]. PMID- 4301743 TI - The effect of acute anemia on the radiosensitivity of V2 rabbit sarcoma. PMID- 4301744 TI - Case of the month from the AFIP. An exercise in radiologic-pathologic correlation. PMID- 4301745 TI - [Mucoid adenocarcinoma of the endometrium]. PMID- 4301746 TI - [Identification of the herpesvirus by electron microscopy in a curable neurosurgical type of acute necrotizing encephalitis]. PMID- 4301747 TI - [Microradiographic study fo the arterial circulation of the brain]. PMID- 4301748 TI - [Prevention of experimental allergic encephalomyelitis by immunological technics]. PMID- 4301749 TI - [Progressive muscular atrophy of a circumscribed spinal type in a single limb]. PMID- 4301750 TI - [Clinical contribution to the knowledge of amyotrophies of parietal origin]. PMID- 4301751 TI - [Corticotropin-producing tumors illustrated by a case of prostate cancer]. PMID- 4301752 TI - Haemagglutinins from marine sponges. PMID- 4301753 TI - [Primary liver cancer originating from bile ducts with a giant metastasis in the sternum]. PMID- 4301754 TI - [Duodeno-colic fistula of malignant origin]. PMID- 4301755 TI - The neural transmission of herpes simplex virus in mice. Light and electron microscopic findings. PMID- 4301756 TI - Histologic study of tissue reaction in canaries, and chicken embryos infected with a pox agent, isolated from parakeets. PMID- 4301757 TI - Comparative metabolism of two vinyl phosphorothionate isomers (thiono phosdrin) by the mouse and the fly. PMID- 4301758 TI - [Hypokalemic hypertension]. PMID- 4301759 TI - [Adenovirus infections of the upper respiratory tract and its various complications]. PMID- 4301760 TI - On the role of microtubules in movement and alignment of nuclei in virus-induced syncytia. AB - Infection of baby hamster kidney (BHK21-F) cells with the parainfluenza virus SV5 causes rapid and extensive cell fusion. Time-lapse cinematography shows that when cells fuse, their nuclei migrate straight to the center of the syncytium at rates of 1-2 micro/min. Nuclei are often arranged in long, tightly packed, parallel rows in syncytia derived from the fibroblastic BHK21-F cells. Polarization microscopy shows birefringent material between and parallel to these rows of nuclei, and electron microscopy shows bundles of cytoplasmic microtubules, approximately 250 A in diameter, and filaments, approximately 80 A in diameter, parallel to and between the rows of nuclei. Colchicine treatment causes disappearance of microtubules from BHK21-F cells and an apparent increase in the number of 80-A filaments. Although colchicine-treated, SV5-infected cells fuse, their nuclei do not migrate or form rows but remain randomly scattered through the syncytial cytoplasm. Incubation at 4 degrees C does not disrupt microtubules in BHK21-F cells. Rows of nuclei have been isolated from SV5-induced syncytia, and the nuclei in them have been found to be intimately associated with microtubules but not with other cytoplasmic structures. These results suggest that microtubules demarcate cytoplasmic channels through which nuclei migrate and that they may also be involved in the mechanism of nuclear movement. PMID- 4301761 TI - Ovarian lipoid cell tumor: urinary steroid response to adrenocorticotropin and chorionic gonadotropin. PMID- 4301762 TI - Traumatic hypopituitarism occurring before puberty: survival 35 years untreated. PMID- 4301763 TI - Response of hyperlipemic subjects to carbohydrates, pancreatic hormones and prolonged fasting. PMID- 4301764 TI - Adrenocortical function in Stein-Leventhal syndrome. PMID- 4301765 TI - A case of glucocorticoid-responsive hyperaldosteronism. PMID- 4301766 TI - Effects of cyclic 3',5'-adenosine monophosphate and dibutyryl cyclic 3',5' adenosine monophosphate on basal and stimulated thyroid function. PMID- 4301767 TI - Aqueous vasopressin provocative test of anterior pituitary function. PMID- 4301768 TI - [Considerations on a new case of asbestosis associated with lung cancer]. PMID- 4301769 TI - Inhibitory effect of the beta-sympatolytic drug propranolol on lipolysis induced by noradrenaline ACTH in normal and hyperthyroid rats. PMID- 4301771 TI - [Changes in anterior pituitary function due to electric stimulation of the hypothalamus]. PMID- 4301770 TI - [A study of ACTH and cortisone antagonism in combination with anticoagulants on the basis of blood coagulation and capillary resistance]. PMID- 4301773 TI - [ACTH secretory function of the pituitary gland transplanted to the kidney cortex of rats]. PMID- 4301772 TI - [Pituitary-adrenal function in rats with hereditary diabetes insipidus]. PMID- 4301774 TI - [Study on the ACTH releasing mechanism by micro-injection of CRF in the anterior pituitary gland]. PMID- 4301775 TI - [Role of the associated systems to the hypothalamus-pituitary-adrenal functions]. PMID- 4301776 TI - [Biosynthesis and feedback mechanism of ACTH]. PMID- 4301777 TI - [Intensive program for the control of tuberculosis in a selected area]. PMID- 4301778 TI - Inhibition of cell growth in vitro by adenosine 3',5'-monophosphate. AB - Adenosine 3',5'-monophosphate, at a concentration of 40 micrograms per milliliter, inhibits the growth of HeLa and strain L cells in culture. The inhibition becomes progressively greater during the incubation of the cells. Adenosine 5'-monophosphate and adenosine, metabolites of adenosine 3',5' monophosphate, do not affect the growth of either cell culture. This suggests that 3',5'-monophosphate enters the cell without alteration. Dibutyryl-adenosine 3',5'-monophosphate, reported to have a greater activity than adenosine 3'5' monophosphate on several tissues, inhibited the growth of the cells much less. PMID- 4301779 TI - Staphylococcal nuclease: size and specificity of the active site. AB - The dissociation constants and standard free energies of complex formation determined with staphylococcal nuclease and a series of 5' phosphoryloligothymidyl derivatives of increasing chain length suggest that maximum stability is reached with an oligonucleotide containing three nucleotide units. A proposed model of the active site that contains other knowledge of the specificity and the catalytic mechanism of this enzyme postulates the existence of three nonequivalent phosphate binding subsites and a closely related phosphodiester hydrolytic subsite. PMID- 4301780 TI - Peptides. PMID- 4301781 TI - Protection against hypertension due to renal allograft rejection by portacaval transposition and renal artery stenosis in dogs. PMID- 4301782 TI - Central venous pressure and blood volume determinations after alpha-adrenergic blockade in experimental posthemorrhagic shock in dogs. PMID- 4301783 TI - [Contribution on the mechanism of corticosteroid hormone action on mitochondrial metabolism in rat brain and heart]. PMID- 4301784 TI - [Functional behavior of nuclear volumes in the adrenal cortex zones]. PMID- 4301785 TI - [Additional electron microscopic studies on epitheloid vascular-wall cells; observations on glomus tumors (Masson)]. PMID- 4301786 TI - [On the chemodifferentiation of the neurosecretory hypothalamic nuclei in the rat]. PMID- 4301787 TI - Nuclear inclusion bodies in vaginal smears. PMID- 4301788 TI - Enzymatic changes in fluorescent alveolar macrophages of the lungs of cigarette smokers. PMID- 4301789 TI - Regulatory phenomena in mammalian serine metabolism. PMID- 4301790 TI - "Vestigial" enzymes during embryonic development. PMID- 4301792 TI - Studies on the role of RNA and protein synthesis in the lipolytic action of growth hormone in isolated fat cells. PMID- 4301791 TI - Regulation of gluconeogenesis and glycolysis: studies of mechanisms controlling enzyme activity. PMID- 4301793 TI - Microfluorometric study of responses of the cytosol to mitochondrial substrates. PMID- 4301794 TI - The redox state of nicotinamide adenine dinucleotide in the cytoplasm and mitochondria of rat liver. PMID- 4301795 TI - The redox state of nicotinamide adenine dinucleotide in the cytoplasm and mitochondria of rat liver. General discussion. PMID- 4301796 TI - Studies on the biosynthesis of NAD by a direct method of tracing metabolism in vivo. PMID- 4301797 TI - Swine diseases in Japan. PMID- 4301798 TI - Investigation of the HI titre of Japanese encephalitis of swine on Taiwan, Republic of China. PMID- 4301799 TI - Regional epizootiology and prophylaxis of foot-and-mouth disease (India). PMID- 4301800 TI - The incidence and distribution of the different types of the foot-and-mouth disease virus in India. PMID- 4301801 TI - [Seroneutralization of sub-types A of foot-and-mouth disease virus on a cellular system. Establishment of a relation between the titre of the serum and the titre of the virus]. PMID- 4301802 TI - Epizootiology and prophylaxis of foot-and-mouth disease in Iran. PMID- 4301803 TI - [Study in the Razi Institute of foot-and-mouth disease virus strains isolated in the Middle East from 1962 to 1967. Influence on the control of foot-and-mouth disease]. PMID- 4301804 TI - The eradication of foot-and-mouth disease in Thailand. PMID- 4301805 TI - [Epizootiology and regional control of foot-and-mouth disease in domestic animals]. PMID- 4301807 TI - [Morphological changes in the diencephalon and the telencephalon following disorders of the regulatory system adenohypophysis--adrenal cortex. II. Results in the guinea pig following administration of metopirone (SU 4885)]. PMID- 4301806 TI - [The status of the liver in essential fatty acid deficiency and dietary cholesterol loading]. PMID- 4301808 TI - [Comparative histological, histochemical and electron microscopic studies of the lacrimal glands. V. Cattle]. PMID- 4301809 TI - [Comparative histological, histochemical and electron microscopic studies of lacrimal glands. IV. Dog]. PMID- 4301810 TI - [Functional morphology of the interrenal organ of the Rana temporaria L]. PMID- 4301811 TI - Effects of various peptides on aldosterone production of sodium deficient rats. PMID- 4301812 TI - [New practical methods for clinical assessment of adrenal cortex function. Experience with a gas chromatography method for the quantitative determination of free C21-17-hydroxycorticosteroids in plasma and urine]. PMID- 4301813 TI - Oxandrolone effect on growth and bone age in idiopathic growth failure. PMID- 4301814 TI - Stimulation of growth hormone secretion in monkeys by adrenalin, pitressin and adenosine-3'5'-cyclic monophosphoric acid (3'5'-AMP). PMID- 4301815 TI - The impaired response to metyrapone in patients taking oestrogen. PMID- 4301816 TI - Dissociation of stimulatory effects of corticotrophin on adrenal corticosterone and protein synthesis following hypophysectomy. PMID- 4301817 TI - Microchemical assays of glucose and glucose-6-phosphate in mammalian pancreatic beta-cells. PMID- 4301818 TI - Acute enzyme histochemical changes in the zona glomerulosa of the rat adrenal cortex. II. The effect of bilateral nephrectomy either alone or followed by peritoneal dialysis with 5 percent glucose. PMID- 4301819 TI - Effect of angiotensin on sympathetic nerve activity. PMID- 4301821 TI - The mechanism of the partial inhibition of fermentation in yeast by nickel ions. PMID- 4301820 TI - Tumors of biliary epithelium and ulcerative colitis. PMID- 4301822 TI - The reaction of pituitary interstitial cell-stimulating hormone with periodate. PMID- 4301824 TI - A study of the mechanisms of cutaneous sensory loss in leprosy. PMID- 4301823 TI - The interaction of N-ethylmaleimide and ACTH on isolated fat cells. PMID- 4301825 TI - [A lesser-known form of angiomatosis, angiosclerosis of Favre and Fiessinger]. PMID- 4301826 TI - [Viral pleuro-pulmonary diseases. 3. Lung diseases and adenovirus infections in Dakar]. PMID- 4301827 TI - [Hyperesthesia and nerve anastomosis]. PMID- 4301828 TI - Influence of angiotensin on the hemodynamic response to exercise in normotensive subjects. PMID- 4301829 TI - Evaluation of a synthetic 25 amino acid corticotrophin in normal man. PMID- 4301830 TI - Studies on insulin secretion in vitro from isolated islets of the rat pancreas. PMID- 4301831 TI - Renin-angiotensin-aldosterone system and sodium balance in experimental renal hypertension. PMID- 4301832 TI - Inhibition of vasopressin-induced ACTH release from the pituitary by glucocorticoids in vitro. PMID- 4301833 TI - Inhibition by pentobarbital of ether-induced ACTH secretion in the rat. PMID- 4301834 TI - Effects of glucagon on carbohydrate synthesis and enzyme activity in rat liver. PMID- 4301835 TI - Dependence of hormonal yield on the collection method for human pituitary glands. II. LH, ACTH and GH. PMID- 4301836 TI - Time course for corticotrophin release from ectopic pituitary grafts. PMID- 4301837 TI - Effect of exogenous ACTH on precursor utilization in lemming adrenal steroidogenesis. PMID- 4301838 TI - Effect of physical exercise on tissue respiration of endocrine glands. PMID- 4301839 TI - Some endocrine and behavioural effects of chlordiazepoxide in septal-lesioned rats. PMID- 4301840 TI - [Metabolic balance studies during oral administration of Fluocortolone]. PMID- 4301841 TI - Adrenocorticotrophic hormone and acquisition of a passive avoidance response: a replication and extension. PMID- 4301842 TI - Succinic dehydrogenase and cytochrome oxidase of mitochondria of chick liver, heart, and skeletal muscle during embryonic development. PMID- 4301844 TI - The effects of cardiac glycosides and their interaction with catecholamines on glycolysis and glycogenolysis in skeletal muscle. PMID- 4301843 TI - The form of sodium-calcium competition at the frog myoneural junction. AB - The times required for a steady rate of miniature end-plate potential discharge to be reached in response to changes in extracellular [K(+)], [Na(+)], and [Ca(++)] have been measured. In the presence of 15 mM KCl, Ca(++) raises and Na(+) lowers the steady-state mepp frequency; but the depressive effect on Na(+) is not specific: Li(+) can replace Na(+) to a large extent. Mepp frequency has been found to depend on the ratio of [Ca(o) (++)]/[Na(o) (+)]. It is assumed that in the steady state, intracellular sodium will change when extracellular sodium is changed. Because both intracellular and extracellular sodium at motor nerve endings affect acetylcholine release, it is proposed that mepp frequency depends on the ratio [Ca(o)] [Na(i)](2)./[Na(o)](2) Two models are proposed. Firstly, to account for the action of sodium and calcium a carrier is postulated for which Ca(++) and Na(+) compete. The carrier determines a maximum level of intracellular Ca(++) far lower than predicted by the Nernst equation for Ca. Secondly, to account for activation of acetylcholine release by a small influx of Ca(++), the ions are presumed to enter the nerve ending in a two stage process through a small intermediate compartment and to act on the acetylcholine release site in this region rather than after entering directly into the cell. PMID- 4301845 TI - The circulatory effects of catecholamines and ouabain in glucocorticoid-deficient animals. PMID- 4301846 TI - [On corticosteroid osteopathies]. PMID- 4301847 TI - [Remote results of the surgical treatment of primary cancer of the liver and the extrahepatic bile ducts]. PMID- 4301848 TI - [Endemic nephropathy in Yugoslavia]. PMID- 4301849 TI - Selective retention of corticosterone by limbic structures in rat brain. PMID- 4301850 TI - Conversion of angiotensin I to angiotensin II by cell-free extracts of dog lung. PMID- 4301851 TI - Antineoplastic activity of aflatoxin B1. PMID- 4301852 TI - [Influence of hydrochlorothiazide and other sulfamoyl diuretics on the activity of 3',5'-AMP phosphodiesterase in rat kidney]. PMID- 4301853 TI - Histochemical method for demonstrating Na-K-ATPase and K-phosphatase at the fine structural level. PMID- 4301854 TI - An analysis of some inhibitory mechanisms in the spinal cord of the frog (Xenopus laevis). PMID- 4301855 TI - [High energy phosphates and O2 consumption of frog sartorius after change from in vivo to in vitro conditions]. PMID- 4301856 TI - Secobarbital and nocturnal physiological patterns. PMID- 4301857 TI - The relationship of glucocorticoids to the early changes of liver triglycerides content after partial hepatectomy in rats. PMID- 4301858 TI - [Echo virus infections in Switzerland during the past 12 years]. PMID- 4301859 TI - Studies on the fixation and development of cellular transformation by Rous sarcoma virus. PMID- 4301860 TI - Evidence that gene 56 of bacteriophage T4 is a structural gene for deoxycytidine triphosphatase. PMID- 4301861 TI - In vitro replication of mouse sarcoma virus (Moloney strain) in bovine embryo skin cells. PMID- 4301862 TI - [On ways of reducing the toxic effects of antitumorous preparations]. PMID- 4301863 TI - [Electrophysiologic studies of the sensory nerve apparatus of the stomach in cancer]. PMID- 4301864 TI - [Detection of sialic acids in metastases of cancer of the stomach by the histochemical method]. PMID- 4301865 TI - [Experimental-histological study of the histogenesis of various forms of angiofibromatosus]. PMID- 4301866 TI - [Status and morphological characteristics of the adrenal cortex of rats during carcinogenesis induced by a minimal dose of strontium-90]. PMID- 4301867 TI - [The susceptibility of the white mouse at varying ages for myotropic F. & M. strains]. PMID- 4301868 TI - [Pickwick's syndrome and the primary alveolar hypoventilation syndrome]. PMID- 4301869 TI - [Clinical and electrophysiologic characteristics of peripheral nerve disorders in metachromatic leukodystrophy (7 cases)]. PMID- 4301870 TI - [On the connection between carcinosarcoma of the breast with giant fibroadenoma and mastopathy]. PMID- 4301871 TI - [On the problem of the histogenesis of stomach cancer]. PMID- 4301872 TI - [Early histochemical changes in the liver of young rats during protein-choline insufficiency]. PMID- 4301873 TI - An epidithiapiperazinedione antiviral agent from Aspergillus terreus. PMID- 4301874 TI - A critical evaluation of the contamination, by lysosomes, of preparations of outer membrane of mitochondria. PMID- 4301875 TI - Localization of phospholipase A2 in outer membrane of mitochondria. PMID- 4301877 TI - Fructose 1,6-diphosphatase from rabbit liver. XI. Relation between the adenosine 5'-monophosphate binding and the allosteric inhibition. PMID- 4301876 TI - Early effects of gibberellic acid on barley aleurone layers. PMID- 4301878 TI - Enzymatic phosphorylation of serine by inorganic pyrophosphate. PMID- 4301879 TI - Negative cooperativity in enzyme action. The binding of diphosphopyridine nucleotide to glyceraldehyde 3-phosphate dehydrogenase. PMID- 4301880 TI - Adenosine 5'-phosphorothioate. A nucleotide analog that is a substrate, competitive inhibitor, or regulator of some enzymes that interact with adenosine 5'-phosphate. PMID- 4301881 TI - Interaction between energy charge and metabolite modulation in the regulation of enzymes of amphibolic sequences. Phosphofructokinase and pyruvate dehydrogenase. PMID- 4301882 TI - [Studies on the oxidative fraction obtained by chymotrypsin hydrolysis of glyceraldehyde-3-phosphate dehydrogenase]. PMID- 4301883 TI - [Electron spin resonance studies of catalase complexes]. PMID- 4301884 TI - Purification and properties of sugar-non-specific nuclease in pupa of silkworm, Bombyx mori Linne. PMID- 4301885 TI - Factors affecting the cation requirement of a halophilic NADH dehydrogenase. PMID- 4301886 TI - Reactions of DPN+ and pyruvate. PMID- 4301888 TI - A method for the determination of estriol in urine during pregnancy. PMID- 4301887 TI - Plasma levels of immunoreactive corticotrophin in patients with Cushing's syndrome. AB - Plasma levels of immunoreactive corticotrophin (A.C.T.H.) have been determined in 56 patients with Cushing's syndrome by means of a homologous radioimmunoassay. In untreated Cushing's disease (bilateral adrenal hyperplasia due to excessive A.C.T.H. secretion from the pituitary) plasma values ranged from 40 to 200 mumug./ml., between 8 and 10 a.m., compared with a range in normal subjects of 12 to 60 mumug./ml. Considerably raised levels, often above 2,000 mumug./ml., were found in patients with Cushing's disease after bilateral adrenalectomy. A.C.T.H. concentrations were usually higher in patients with bilateral adrenal hyperplasia associated with ectopic A.C.T.H. production than in patients with untreated Cushing's disease; whereas plasma A.C.T.H. was undetectable in the presence of an adrenocortical tumour. All patients with Cushing's syndrome failed to show the normal circadian rhythm of circulating A.C.T.H. levels. PMID- 4301889 TI - A study of the determination of lactic dehydrogenase isoenzymes by means of agar gell and strach-agar gel zymograms. PMID- 4301890 TI - Effects of "dream deprivation" on dream content: an attempted cross-night replication. PMID- 4301891 TI - [Thiabendazole effect in dracunculosis]. PMID- 4301892 TI - [Regurgitation esophagitis treated with Gaviscon]. PMID- 4301893 TI - [The effect of hormones on the status of the basal membrane of regenerating skin]. PMID- 4301894 TI - [A contribution to the problem of intravenous urography in myeloma]. PMID- 4301895 TI - [On the diagnosis of brain tumors with Hg197-neohydrine gamma-encephalography]. PMID- 4301896 TI - [Acute hemorrhagic enteritis caused by Welchia perfringens in zebus of Senegal]. PMID- 4301897 TI - [Study of ready-to-use thin films for the chromatography of aflatoxins]. PMID- 4301898 TI - [Bilateral arrhenoblastoma of the ovaries with malignization]. PMID- 4301899 TI - [Malignant androsteromas of the adrenals (2 cases)]. PMID- 4301900 TI - [Changes in the function of the adrenal cortex and the insecretory function of the stomach in patients with cancer of the stomach]. PMID- 4301901 TI - [Results of gastrectomy in cancer of the cardia and lower third of the esophagus]. PMID- 4301902 TI - [Reproduction of Rous sarcoma virus in vitro (strain 6)]. PMID- 4301903 TI - [Increase in the resistance of cells to the toxic effect of a chemical carcinogen by virus SV40]. PMID- 4301904 TI - [Studies of the ependyma and ependymal organs in the diencephalon of lower vertebrates (Neoceratodus, Urodela, Anura)]. PMID- 4301905 TI - [Karyometric studies of the clarification of the osmo-or volume regulatgry role of the subcommissural organ and its functional connection with the adrenal cortex]. PMID- 4301906 TI - Nephrolithiasis in inflammatory bowel disease. PMID- 4301908 TI - Characterization of N4,O2'-dimethylcytidine, a rare nucleoside constituent of Escherichia coli 16-S RNA. PMID- 4301907 TI - Canine submandibular-gland hyaluronidase. Identification and subcellular distribution. AB - 1. Submandibular glands from four species of mammal have been shown to contain a hyaluronidase active at acid pH; glands from dog and cat had a much higher content of this enzyme than has been found in other sources. 2. Product formation from hyaluronate after 24hr. incubation was almost the same as with testicular hyaluronidase, indicating that the enzyme is an endo-poly-beta-hexosaminidase. 3. When submandibular-gland homogenates were fractionated by the scheme developed for liver by de Duve, Pressman, Gianetto, Wattiaux & Appelmans (1955), all the enzymes assayed, except cytochrome c oxidase, were found to occur partly in the soluble fraction and partly in the particulate fractions. Among the particular fractions, the highest specific activity was found in the heavy-mitochondrial fraction for cytochrome c oxidase, in the microsomal fraction for alkaline phosphatase and in the light-mitochondrial fraction for acid phosphatase, beta-N acetylhexosaminidase and acid-active hyaluronidase. 4. Release of the enzyme activity from the sedimentable fractions occurred in 0.1% Triton X-100 or after high-speed homogenization. 5. Stimulation of dogs by pilocarpine was found to decrease the hyaluronidase content of the submandibular gland by 5% and to cause the occurrence of a corresponding amount of acid-active hyaluronidase in the submandibular saliva. 6. The results are discussed in relation to the subcellular localization of hyaluronidase. PMID- 4301909 TI - The modification of nucleosides and nucleotides. X. Evidence for the important role of inosine residue in codon recognition of yeast alanine tRNA. PMID- 4301910 TI - RNA fractions in normal rat liver and Morris 5123D hepatoma. PMID- 4301911 TI - Studies on tissue specificities of nuclear and ribosomal RNA using the DNAxRNA hybridization technique. PMID- 4301912 TI - Sucrose density-gradient analysis of Euglena gracilis RNA isolated with macaloid. PMID- 4301913 TI - Purification of nucleoside triphosphatases from pea seedling ribosomes. PMID- 4301914 TI - RNA with amino acid-acceptor activity isolated from an oncogenic virus. PMID- 4301915 TI - A phosphate activated glutaminase in rat liver different from that in kidney and other tissues. PMID- 4301917 TI - The fate of parenterally injected 14C-hyaluronidase. PMID- 4301916 TI - [Enzymes of energy-producing metabolism in human adipose tissue]. PMID- 4301918 TI - [Comparative study of metabolic changes in rat liver after administration of ethanol and other compounds. II. Intraperitoneal injection of fructose]. PMID- 4301919 TI - [Influence of vitamin D3 on the activity of thyrocalcitonin in rat thyroid glands]. PMID- 4301920 TI - Purification of collagenase. IV. Separation and identification of clostridial collagenases by disc electrophoresis on polyacrylamide gel. PMID- 4301921 TI - [Receptors of neurotransmitters. IV. Receptor of serotonin and sialic acid metabolism in smooth muscle]. PMID- 4301922 TI - [Enzymatic estimation of fructose-1-phosphate]. PMID- 4301923 TI - Pseudogout, hyperparathyroidism, and Carpal-Tunnel syndrome. A case report. PMID- 4301924 TI - [On a simple method of "immunization" against cancer--an expanded reproduction attempt]. PMID- 4301925 TI - Cytomegalic inclusion disease of the inner ear. PMID- 4301926 TI - [Plasmatic angiotensinase activity in normal pregnancy and the puerperium]. PMID- 4301927 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 52-1968. PMID- 4301928 TI - Input-output relation of the vestibular system during sleep and wakefulness. PMID- 4301929 TI - [Glomus tumor]. PMID- 4301932 TI - Bronchiolar carcinoma of the lung. PMID- 4301930 TI - [Isolation of adenovirus type 2. Study of an outbreak in the Casa de Cuna]. PMID- 4301931 TI - [Bacteriological study and current antibiogram of infections caused by anaerobic bacteria]. PMID- 4301933 TI - Adenosine monophosphates and phosphorylase activity in frog stomachs. PMID- 4301934 TI - Adenosine monophosphates and glycogenolysis in frog gastric mucosa. PMID- 4301936 TI - Inhibition of angiotensin and its protection by a cofactor in blood. PMID- 4301935 TI - Converting enzyme in CC14-treated renal hypertension. PMID- 4301937 TI - Interrelationship of physical factors affecting sodium reabsorption in the dog. PMID- 4301938 TI - Effects of angiotensin on stroke volume and regional blood flow and resistance. PMID- 4301939 TI - [Radiotherapy of pineal tumors; assessment of its effect with consecutive oil ventriculography]. PMID- 4301940 TI - [Case of non-tumoral stenosis of the sylvian aqueduct]. PMID- 4301941 TI - [Three patterns on the glass surface produced by cultured astrocytoma glioblastoma-series]. PMID- 4301942 TI - [Treatment of malignant brain tumors by BAR therapy]. PMID- 4301943 TI - [Mechanism of synthesis of glucose-1,6-diphosphate in human red corpuscles]. PMID- 4301944 TI - [On the inhibition by excess substrate of beta-hydroxysteroid dehydrogenase from Pseudomonas testosteroni]. PMID- 4301945 TI - [On the NAD and NADH2 content of liver, heart and kidney of normal and alcohol treated rats]. PMID- 4301946 TI - [Purine nucleoside phosphorylase activity in serum, liver and spleen tissue during the course of experimental infection with MHV-3 virus]. PMID- 4301947 TI - Inhibitory effect of dehydroacetic acid on induction of hepatoma in rats fed 4 (dimethylamino) azobenzene. PMID- 4301948 TI - Partial purification and properties of nicotinamide-adenine dinucleotide nucleosidase and interaction between enzyme and its protein inhibitor. PMID- 4301949 TI - Cellular oxidation-reduction stae of some NAD-linked reactions in diabetic rat liver, and the effect of coenzyme Q administration. PMID- 4301950 TI - [Study on fatty acid metabolism in the myocardium with reference to epinephrine sensitive lipase in vitro]. PMID- 4301952 TI - [Basic study on chemotherapy of urinary tract infection. II. Effect of urine pH on antibacterial activity of chemotherapeutics on Escherichia coli]. PMID- 4301951 TI - [Role of noradrenaline and angiotension on cerebral circulation in juvenile essential hypertension]. PMID- 4301953 TI - Brain tumors induced with Rous sarcoma virus, Schmidt-Ruppin strain. I. Induction of brain tumors in adult mice with Rous chicken sarcoma cells. PMID- 4301954 TI - Studies on poliovirus inhibitors in sera of domestic animals. 3. A comparison of physico-chemical properties of poliovirus inhibitors and specific antibodies. PMID- 4301955 TI - A preliminary report on infection of the lizard, Takydromus tachydromoides, with Japanese encephalitis virus. PMID- 4301956 TI - Isolation of Japanese encephalitis virus from mosquitoes by means of the plaque formation method with chick embryo fibroblast monolayers. PMID- 4301957 TI - A simple method for the serum neutralization with Japanese encephalitis (JE) virus utilizing plaque inhibition by agar-diffused antibody. PMID- 4301958 TI - Effects of dibutyryl cyclic 3',5'-adenosine monophosphate on the renal function. PMID- 4301959 TI - [The climacteric syndrome and its therapy in gynecological practice]. PMID- 4301960 TI - [Research on the possibility of the use of non-silica sand in a foundry to prevent silicosis]. PMID- 4301961 TI - [The practitioner and indications for anticancerous chemotherapy]. PMID- 4301962 TI - [Melanocytes and the hormonology of pigment reactions]. PMID- 4301963 TI - [Depot-ACTH in the ambulatory management of obstructive bronchial diseases]. PMID- 4301964 TI - [The properties of new substrates for the determination of pancreas enzymes]. PMID- 4301965 TI - [Studies on the effect of nicotinic acid on stimulated lipolysis]. PMID- 4301966 TI - [Various aspects in the metabolism of glutamic acid in the different structures of the motor analyzer]. PMID- 4301967 TI - [Thin-layer chromatography for biological alkylation agents]. PMID- 4301968 TI - Distribution volume and metabolic clearance rate of renin in anesthetized nephrectomized dogs. PMID- 4301969 TI - Statistical analysis of data from countercurrent distribution. I. Method for estimation of quantity and partition coefficient of each compound in the distribution. PMID- 4301970 TI - Statistical analysis of data from countercurrent distribution. II. Some applications and limitations of the method. PMID- 4301971 TI - A method for quantitative determination of phosphonate phosphorus in the presence of organic anc inorganic phosphates. PMID- 4301972 TI - The use of specific macromolecular complexing agents for enzyme purification: beef heart dehydrogenase. PMID- 4301973 TI - [Change in sensitivity toward penicillin and penicillinase activity in cultures of Staphylococci after acquiring resistance toward ristomycin, sekazin and novobiocin in vitro]. PMID- 4301975 TI - [Experiments on the induction of transplantation immunity against o aminoazotoluene-hepatomas in syngeneic Fl-hybrid mice]. PMID- 4301974 TI - A study of the physical properties of the immunizing antigen of foot-and-mouth disease virus and the effect of various inactivating agents on its structure. PMID- 4301976 TI - Neuro-ophthalmology. PMID- 4301977 TI - Adenyl cyclase activity in the chronically denervated cat heart. PMID- 4301978 TI - Adenyl cyclase in plasma membrane preparations of sea urchin eggs and its increase in activity after fertilization. PMID- 4301979 TI - Rates of exchange of isotopic hydrogen between reduced substrates of coupled NAD dependant dehydrogenases. PMID- 4301980 TI - The effect of cyclic 3',5'-AMP on catabolite repression of beta-galactosidase synthesis in Escherichia coli. PMID- 4301981 TI - Solubilization of bound lactate dehydrogenase by NADH in homogenates of trout skeletal muscle as a function of tissue concentration. PMID- 4301983 TI - Endocrine ophthalmopathy. PMID- 4301984 TI - [The indication for the treatment of malignant and semimalignant extremity neoplasms]. PMID- 4301985 TI - Sequence determination in nucleic acids. PMID- 4301986 TI - Oxidative phosphorylation. PMID- 4301988 TI - Effects of catecholamines on the gastrocnemius muscle of the domestic fowl. PMID- 4301987 TI - Absence of effects of prostaglandins E1 and E2 on ganglionic transmission. PMID- 4301989 TI - Formation and identification of 3-keto-5-aminohexanoic acid, a probable intermediate in lysine fermentation. PMID- 4301990 TI - Inhibition of enzyme activities by free fatty acids. PMID- 4301992 TI - Effect of age on oxidative phosphorylation in the rat. PMID- 4301991 TI - Diacyl myoinositol monomannoside from Propionibacterium shermanii. PMID- 4301993 TI - Replication and complementation of human adenoviruses and simian papovavirus at an elevated temperature. AB - The simian papovavirus SV40 replicated as well in simian cells incubated at 41 C as in cells incubated at 37 C, although the latent period was shortened at the elevated temperature. Human adenoviruses differed in their responses to the elevated temperature. Some serotypes, such as 3, 4, 5, 7, 8, 16, and 21, replicated as well, or almost as efficiently, in human cells incubated at 41 C as in cells incubated at 37 C, whereas with other serotypes, such as 1, 2, 6, 12, and 14, maximal yields in cultures incubated at 41 C were much lower than the yields from companion cultures incubated at 37 C. This difference was also detected in simian cells co-infected with SV40 and a human adenovirus; maximal complementation occurred with some serotypes at the elevated temperature but not with other serotypes. The degree of complementation observed in the simian cells at 41 C was directly correlated with the ability of the adenovirus to replicate at 41 C in human cells. Therefore, the capacity of SV40 to serve as a helper virus is not affected by the elevated temperature, showing that the complementation event supplied by the simian virus is heat-stable between 37 and 41 C. Maximal complementation appeared to depend upon a characteristic present in the adenovirus genome. PMID- 4301994 TI - Incorporation of iododeoxyuridine into cellular deoxyribonucleic acid synthesized after infection with simian virus 40. AB - Primary monkey kidney cells (Cerocpithecus aethiops) in the stationary phase of growth were labeled with (14)C-thymidine for 24 hr prior to infection with simian virus 40 (strain 777). (3)H-deoxyadenosine and 5-iodo-2'-deoxyuridine (IUdR) were added to some of the cultures 24, 48, or 72 hr after infection; 24 hr later the deoxyribonucleic acid (DNA) was extracted from these cultures and centrifuged in a CsCl density gradient. The portion of DNA which had become heavier because of incorporation of IUdR could be seen as a second peak in the sedimentation profile. This peak contained (14)C as well as (3)H activity. The possibility that the (14)C-labeled cellular DNA might be degraded and used for the synthesis of viral DNA could be excluded. On the basis of these results, it must be assumed that the infection of monkey kidney cells with simian virus 40 induces the synthesis of cellular DNA. PMID- 4301995 TI - Infective substructures of Sendai virus from infected Ehrlich ascites tumor cells. AB - Increase of infectivity for embryonated eggs was observed in Ehrlich ascites tumor cells after intraperitoneal inoculation of Sendai virus into tumor-bearing mice. Virus-induced actinomycin-resistant ribonucleic acid consisting of 14S, 18S, 22S, 35S, and 48S was synthesized, and S antigen was produced in infected cells. The infectivity was suggested to be due to viral ribonucleoprotein for the following reasons: (i) the infectivity was unaffected by V antiserum but was abolished by whole hyperimmune serum, (ii) the infectivity was resistant to ribonuclease, (iii) virus particles were found neither in cells nor on red blood cell stroma treated with cellular extracts, (iv) structures similar to Sendai virus ribonucleoprotein with a maximal length of 10,500 A were observed in cellular extracts. PMID- 4301996 TI - [Action site and results of corticoid therapy in leukoses?]. PMID- 4301997 TI - Factors controlling the interconversion of enzyme-substrate compounds of pig heart lactate dehydrogenase. PMID- 4301998 TI - Some aspects of the mechanisms involved in adrenergic neurotransmission. PMID- 4301999 TI - The antiviral activity of 3,4-dihydro-1-isoquinolineacetamide hydrochloride in vitro, in ovo, and in small laboratory animals. PMID- 4302000 TI - Preservation of infectious cytomegalovirus. PMID- 4302001 TI - [The status of the liquor in glioma of the cerebral hemispheres extending to the cortex and membranes]. PMID- 4302003 TI - The proteins specified by herpes simplex virus. I. Time of synthesis, transfer into nuclei, and properties of proteins made in productively infected cells. PMID- 4302002 TI - Nucleotide accumulations in Escherichia coli infected with some bacteriophage T4 amber mutants. PMID- 4302004 TI - Control of DNA synthesis in cells infected with polyoma virus. PMID- 4302005 TI - Shared group-specific antigen of murine and feline leukemia viruses. PMID- 4302006 TI - Observations on polyoma virus filaments. PMID- 4302007 TI - Absence of homology between polyoma or SV40 viral DNA and mitochondrial DNA from virus-induced tumors. PMID- 4302008 TI - Comparative electron micrographs of sowthistle yellow vein and vesicular stomatitis viruses. PMID- 4302009 TI - Structural relationships between the RNA of mammary tumor virus and those of other RNA tumor viruses. PMID- 4302010 TI - [Neurogenic tumors of the thyroid gland]. PMID- 4302011 TI - Perihepatic hematoma. A benign condition simulating malignancy on the hepatic photoscan. PMID- 4302012 TI - Granular cell myoblastoma of duodenum. A review of literature and case report. PMID- 4302013 TI - Defectiveness of interferon production and of rubella virus interference in a line of African green monkey kidney cells (Vero). AB - Vero cells, a line of African green monkey kidney cells, failed to produce interferon when infected with Newcastle disease, Sendai, Sindbis, and rubella viruses, although the cells were sensitive to interferon. Further, infection of Vero cells with rubella virus did not result in interference with the replication of echovirus 11, Newcastle disease virus, or vesicular stomatitis virus, even in cultures where virtually every cell was infected with rubella virus. Under the same conditions, BSC-1 cells and other cells of primate origin produced interferon and showed rubella virus interference. The results indicate that the presence of rubella virus in the cell does not in itself exclude multiplication of other viruses and that rubella virus interference appears to be linked to the capability of the cell to produce interferon. PMID- 4302014 TI - Herpes simplex virus products in productive and abortive infection. 3. Differentiation of infectious virus derived from nucleus and cytoplasm with respect to stability and size. AB - Approximately 67% of infectivity is associated with the nucleus 8 hr after productive infection of HEp-2 cells with herpes simplex virus. Comparison of nuclear and cytoplasmic infectious virus and macromolecular aggregates labeled with (3)H-thymidine or with (3)H-choline revealed the following. (i) Cytoplasmic infectious virus and macromolecular aggregates banded in CsCl at a density corresponding to enveloped nucleocapsids. The virus was relatively stable; there was only 50% loss of infectivity and only 16% of the virions became disaggregated. (ii) Nuclear macromolecular aggregates banded in CsCl solution at a density corresponding to unenveloped nucleocapsids and, moreover, both the infectious virus and aggregates were highly unstable. (iii) In sucrose density gradients, the nuclear macromolecular aggregates and infectivity sedimented as a single band and migrated more slowly than the corresponding cytoplasmic material. (iv) The infectivity of nuclear and cytoplasmic virus is readily inactivated by digestion with phospholipase C and with pronase. We conclude the following. (i) Cytoplasmic virus consists of enveloped nucleocapsids. (ii) Nuclear virus consists of nucleocapsids covered with lipid or partially enveloped. (iii) The molecular integrity of viral lipids is essential for infectivity. (iv) The envelope protects the nucleocapsid and accelerates adsorption to cells; it is not, however, inherently essential for infectivity. PMID- 4302015 TI - Chromosomal and autoradiographic studies of cells infected with herpes simplex virus. AB - The induction of chromosomal aberrations by herpes simplex virus (HSV) and the interaction between viral deoxyribonucleic acid (DNA) and chromosomes have been studied (i) by infection of the BHK-21 line of hamster kidney cells at multiplicities ranging from 0.5 to 100 followed by 1-hr pulses of (3)H-thymidine preceding preparation at varying intervals of metaphases and autoradiography, and (ii) by use of (3)H-thymidine-labeled HSV for infection, chromosomal, and autoradiographic analyses at intervals thereafter. The results revealed that (i) chromosomal lesions develop prior to, and thus are independent of, viral DNA synthesis; (ii) HSV is capable of replicating in cells during the late G-2 period or in metaphase; (iii) most of the viral DNA remains unassociated with chromosomes and is not detectable at sites of chromosomal lesions; (iv) the capacity of the virus to cause chromosomal aberrations is four times less sensitive to inactivation by ultraviolet (UV) irradiation than its infectious property; and (v) after large doses of UV, invasion of the nuclei by the irradiated virus is reduced. These observations indicate that the chromosomal lesions induced by HSV result most likely from action of an early enzyme under control of the viral genome. This explanation is proposed also for the effects of adenovirus type 12 on chromosomes. PMID- 4302016 TI - Structure and development of viruses as observed in the electron microscope. IX. Entry of parainfluenza I (Sendai) virus. AB - After attachment, the uncoating of Sendai virus, which was accompanied by dissolution of the plasma membrane and fusion of virus to cell, proceeded quickly. Nucleoprotein filaments were found at stages of transit from virus to cytoplasm. PMID- 4302017 TI - Effects of x-irradiated aqueous solutions on vesicular stomatitis virus. AB - Infectivity of vesicular stomatitis virus was inactivated by suspending the virus in aqueous salt solutions that had previously been subjected to X-irradiation. This viral inactivation did not appear to be attributable to hydrogen peroxide or to long-lived free radicals generated by X-irradiation of the salt solutions. Indirect evidence suggested that the deleterious effects on the virus were caused by chemical species resulting from interaction of free water molecules with anions in the solution. Inactivation of infectivity was associated with distortion of the outer layer of the virion, as determined by electron microscopy, and with consequent impairment of adsorption to otherwise susceptible cells. PMID- 4302018 TI - Electron microscopic study of the morphogenesis of vesicular stomatitis virus. AB - Except for the rate, vesicular stomatitis virus (VSV) grows as well at 25 C as at 37 C in primary chick embryo fibroblast cells and in a pig kidney cell line [PK(H13)]. Maximal yields were reached at about 28 hr at 25 C and 10 hr at 37 C in these cells. Morphogenesis, as observed by electron microscopy, was similar at the two temperatures. The main feature was accumulation of virus in intracytoplasmic vacuoles. Mode of release of VSV has been controversial; both budding (as displayed by myxoviruses) and maturation at membranes of cytoplasmic vacuoles (as with arboviruses) have been claimed. Our observations support the latter view, and the apparent dichotomy in interpretation is discussed. PMID- 4302019 TI - Electron microscopy of herpes simplex virus. 3. Effect of hydroxyurea. AB - The effect of hydroxyurea on the development of herpes virus is mediated through its inhibitory action on deoxyribonucleic acid (DNA) synthesis. Concentrations of the drug that suppress the production of infectious virus cause typical developmental anomalies: failure in formation of the normally dense cores or "complete" viral particles, and either faulty or no envelopment of viral capsids by membranes. The synthesis of viral capsids and virus-stimulated nuclear and cytoplasmic membranes, however, is not interrupted. Combining these results with those of time sequence experiments, the following hypotheses can be presented regarding viral development. Protein synthesis, which is characterized by capsids enclosing cores of low density, precedes DNA synthesis, which is characterized by the appearance of dense cores. Capsids with dense cores are selectively transported to the cytoplasm. Envelopment generally takes place as capsids pass from the nucleus to the cytoplasm. The process of envelopment is also selective, with the result that the majority of particles that have an envelope contain a full quota of DNA. PMID- 4302020 TI - Electron microscopy of herpes simplex virus. IV. Studies with ferritin-conjugated antibodies. AB - Small aggregates of viral antigen were encountered in the nuclear matrix. The capsids did not tag with antibodies specific for the virus or for the host cell. This observation remains unexplained. Nuclear and cytoplasmic membranes, as well as the envelope of the virus, reacted with both types of antibodies and appear, therefore, to contain host cell and viral protein. Large amounts of viral antigen are synthesized within the cytoplasm. This antigen was either diffusely spread or localized at the surface of membranes. The surface of infected cells contains viral antigen, which accumulates as infection progresses. At circumscribed sites, the cell wall becomes altered antigenically and structurally so as to resemble the envelope of the virus. Hypotheses are presented regarding the manner in which cell fusion occurs. PMID- 4302022 TI - Genetic variance in skeletal and dental maturity status of Caucasian dizygotic twins. PMID- 4302023 TI - 3. Effect of morphine and nalorphine on brain phospholipid metabolism. PMID- 4302021 TI - Studies on streaming. I. Inhibition of protoplasmic streaming and cytokinesis of Chaos chaos by adenosine triphosphate and reversal by magnesium and calcium ions. AB - In Chaos chaos streaming, motility, and cytokinesis were inhibited nearly 100% for several hours by 2.5-5 mM sodium adenosine triphosphate (ATP)(1) added to culture fluid. All three effects were completely prevented by the addition of equimolar Mg(++) or Ca(++) ions but not Na(+) to the ATP/culture fluid solution. The effects of ATP were not reproduced by EDTA, EGTA, colchicine, or AMP. Sodium pyrophosphate produced about 50% inhibition at 5 mM. Studies with (14)C-ATP showed that 5 x 10(-5) to 5 x 10(-4) mmole of ATP was firmly associated with each milliliter of packed cells after an hour's incubation at 24 degrees C. Labeling studies also showed that prevention of the ATP effects by Mg(++) ions was not due to a decrease in the amount of ATP associated with the cells. PMID- 4302024 TI - [Differences in activity and intracellular localization of hexokinase between normal liver and hepatomas in the rat]. PMID- 4302025 TI - [Changes of the activity of some liver enzymes following partial denervation of the rat liver of the ductus choledochus]. PMID- 4302026 TI - [On the effect of tolbutamide on the hexadimethrine bromide-induced changes in organs and on the toxicity of histamine, serotonin and various histamine liberators]. PMID- 4302027 TI - An autopsy case of stunted growth with fatty liver cirrhosis, hepatoma, hypogonadism, osteoporosis and lipid pneumonia. PMID- 4302028 TI - Association of thyroid carcinoma and chemodectoma. PMID- 4302030 TI - Gustatory sweating. PMID- 4302029 TI - [On the viral etiology of acute laryngotracheobronchitis in childhood]. PMID- 4302031 TI - Cytological changes of Escherichia coli caused by polymyxin E. PMID- 4302032 TI - Production of interferon-like inhibitor induced by extract from Rous sarcoma. I. Inhibition of Rous sarcoma virus infection and properties of the inhibitor produced. PMID- 4302033 TI - Production of interferon-like inhibitor induced by extract from Rous sarcoma. II. Properties of the inducer in the extract. PMID- 4302034 TI - [An unusual type of cutaneous metastases]. PMID- 4302035 TI - Toxicology and carcinogenic action of pyrrolizidine alkaloids. PMID- 4302037 TI - [Clinical picture of pituitary tumors]. PMID- 4302036 TI - Synergism between cyclopropenoid fatty acids and chemical carcinogens in rainbow trout (Salmo gairdneri). PMID- 4302038 TI - [Heterotopic ACTH-producing tumors]. PMID- 4302039 TI - [Ovarian tumors]. PMID- 4302040 TI - Relation of the centrally evoked pressor effect of angiotensin II to the calcium ion. PMID- 4302041 TI - [Evaluation of the bioelectrical and histochemical phenomena in the ovum cells in birds]. PMID- 4302042 TI - [Teratoma of the fetal sacro-coccygeal region resulting from a difficult delivery]. PMID- 4302043 TI - Periodate oxidation of acid polysaccharides inhibition by the electrostatic field of the substrate. PMID- 4302045 TI - Differences in maturity, physical, and motor traits for boys of high, average, and low gross and relative strength. PMID- 4302044 TI - [Giant adrenal gland tumor (angiographic and pneumographic aspects)]. PMID- 4302046 TI - [Neuromuscular transmission in myasthenia gravis]. PMID- 4302047 TI - [Enzymatic activity in the cerebrospinal fluid in diseases of the nervous system]. PMID- 4302048 TI - [Studies on the oxido-reductive reaction in the cerebrospinal fluid]. PMID- 4302049 TI - [Cellular receptors for animal viruses]. PMID- 4302050 TI - ["Partial study of the corticoadrenal reserve in elderly patients"]. PMID- 4302051 TI - [Adenoid cystic carcinoma in the field of oral surgery and experiences in its irradiation therapy]. PMID- 4302052 TI - Strokes-modern treatment. PMID- 4302053 TI - [Adrenal cortical hormone therapy for induction of ovulation]. PMID- 4302054 TI - [Stiff man syndrome. Clinical, electrologic and therapeutic details]. PMID- 4302055 TI - [The essentially tremulous forms of Parkinson's syndrome. Prognostic importance of a mixed tremor (combined intention tremor and resting tremor)]. PMID- 4302056 TI - [Physical therapy reeducation of primary or secondary peripheral facial paralysis]. PMID- 4302057 TI - [Importance of the intravenous administration of trimipramine in the treatment of depressive states]. PMID- 4302058 TI - [Apropos of a case; study of the concept of psychogenic psychosis]. PMID- 4302059 TI - Serum lipid studies in multiple sclerosis. PMID- 4302061 TI - [Histochemical studies on the glandula orbitalis externa of the white mouse]. PMID- 4302060 TI - Enzyme histochemistry of the cerebral cortex of squirrel monkey and rat. PMID- 4302062 TI - [On the statistical distribution of different measured dimensions in cyto- and histophotometry]. PMID- 4302063 TI - The effect of cortisone and ACTH on behaviour of beta-glucuronidase and beta galactosidase in stomach mucosa of white rat. PMID- 4302064 TI - Isotope scanning of brain tumors using 99mTc. PMID- 4302065 TI - Effect of angiotensin on the dog kidney. PMID- 4302066 TI - Ovarian tumors investigated by histochemical and enzyme histochemical methods. PMID- 4302067 TI - Incidence and histochemical investigation of enzymatically active cells in stroma of ovarian tumors. PMID- 4302068 TI - Review of diagnostic audiometry. PMID- 4302069 TI - Afferent nerve fibers in the external branch of the superior larygneal nerve in the cat. PMID- 4302070 TI - Otolaryngological aspects of thyroid cancer. PMID- 4302071 TI - Facial paralysis in cephalic herpes zoster. PMID- 4302072 TI - Anaphylaxis and skin homograft rejection: effect of simultaneous splenectomy and thymectomy in rats and guinea pigs. PMID- 4302074 TI - Motor-point biopsies in carcinomatous neuropathy. PMID- 4302073 TI - [On pathology and genesis of extra-mammary Paget's disease]. PMID- 4302075 TI - A new ocular syndrome. PMID- 4302077 TI - Trimethoprim. PMID- 4302076 TI - Acquired cytomegalovirus infection. PMID- 4302078 TI - Herpes simplex cervicitis. PMID- 4302079 TI - Idiopathic facial palsy. PMID- 4302080 TI - Osmotic and ionic regulation in gold fish following removal of the corpuscles of Stannius or the pituitary gland. PMID- 4302081 TI - Endocrine factors in the development of transplantable adrenal cortical tumors. I. Inhibition of the growth rate by corticotropin (ACTH). PMID- 4302082 TI - [Cellular conversion induced in vitro by murine sarcoma virus (Moloney strain). An analysis of dose-response curves]. PMID- 4302083 TI - Immunologic studies on Graffi-virus-infected spontaenous Gross leukemia of AKR mice. PMID- 4302084 TI - The differential action of neonatal thymectomy in mice infected with Murine Sarcoma Virus-Harvey (MSV-H). PMID- 4302085 TI - Polyoma virus replication in ascitic cells. PMID- 4302086 TI - Susceptibility of Praomys (Mastomys) natalensis to the Murine Sarcoma Virus Harvey (MSV-H). PMID- 4302087 TI - The basis of the tumorigenicity of BHK 21 cells. PMID- 4302088 TI - Relationships of chromosomal and pathological findings in Rous sarcoma virus induced tumours in the mouse. PMID- 4302089 TI - Contribution to the diagnosis and treatment of tumors of the glomus jugulare. PMID- 4302090 TI - Periodic postoperative mammography. PMID- 4302091 TI - Studies on production and purification of cytochrome C of Candida krusei and its properties. PMID- 4302092 TI - Mode of action of piericidin A on the phosphorylating respiratory chains. PMID- 4302093 TI - Isolation and characterization of a glycopeptide from a mucinous carcinoma in a human stomach. PMID- 4302094 TI - Production of the inducer for macrophage and granulocyte colonies by leukemic cells. PMID- 4302095 TI - Lipids of cancer tissues. 3. Glycolipids of human hepatoma tissue. PMID- 4302096 TI - Further study on the faster running glycolipid in brain. PMID- 4302097 TI - [Changes of statural and osseous growth after medical or surgical therapy in adrenal diseases in childhood]. PMID- 4302098 TI - [Reactivity of the newborn animal to drugs. Preliminary report. I. Comparative action of some biological mediators on isolated portions of the gastrointestinal tract]. PMID- 4302099 TI - [Virological research in 43 newborn infants with acute respiratory diseases]. PMID- 4302100 TI - [Endoerythrocytic bioenzymology in sickle-cell disease and microdrenpanocytosis]. PMID- 4302101 TI - [Brief therapy of viral hepatitis]. PMID- 4302102 TI - [Adjuvant role of the lipopolysaccharide from Bordetella pertussis in the induction of experimental allergic encephalomyelitis. Induction of a subacute form in the rabbit and inhibition of this adjuvant effect]. PMID- 4302103 TI - [Studies of the protective effect of hyperimmune anti-nervous system serum against experimental allergic encephalomyelitis]. PMID- 4302104 TI - [Static and dynamic characteristics of electron spin resonance spectra]. PMID- 4302105 TI - [Determination of free radicals in the retina by electron spin resonance]. PMID- 4302106 TI - [Effect of the potassium ion on the variations of vasopressive action of angiotensin in vivo: determination during extra-renal dialysis]. PMID- 4302107 TI - [Significance of angiography for the diagnosis of trophoblastic tumors its method and the interpretation of its findings]. PMID- 4302108 TI - [Hemorrhagic and necrotic lesions of the adrenal glands (anatomo-clinical study of 32 cases)]. PMID- 4302109 TI - [Functional and histologic disorders of the kidney in 3 cases of severe and chronic potassium deficiency]. PMID- 4302110 TI - [Coarctation of the aorta and renal ischemia]. PMID- 4302111 TI - [Complications of lymphography]. PMID- 4302112 TI - [Apropos of a bilio-intestinal fistula apparently non-lithiasic]. PMID- 4302113 TI - [Blocking of the thyroid gland during brain scintigraphy]. PMID- 4302114 TI - [Uraemic polyneuropathy. A clinical study]. PMID- 4302115 TI - [Adenoma of the lungs]. PMID- 4302116 TI - [Intrathoracic neurogenic tumors]. PMID- 4302117 TI - [Presence of glutathione in normal and tumorous tissues of humans and animals]. PMID- 4302118 TI - [Virogenicity of tumors arising in mice after the administration of cell cultures infected with Rous virus]. PMID- 4302119 TI - [Experimental studies on the relation between the thyroid gland and hypophysis during the larval development and metamorphosis of Xenopus laevis Daudin]. PMID- 4302120 TI - The ultrastructure of the nuclei and the behaviour of the sex chromosomes of human spermatogonia. PMID- 4302121 TI - [Various data on the epidemiology of adenovirus diseases]. PMID- 4302122 TI - [Comparative characteristics of the metabolism of brucellae]. PMID- 4302123 TI - [Prevention of natural focal diseases in connection with assimilation of new regions in Siberia and the Far East]. PMID- 4302124 TI - [Determination of the sensitivity of the plague microbe to antibootics]. PMID- 4302125 TI - [Study of wrist bone development in children. 3. Wrist bone development in simple obesity in a child]. PMID- 4302127 TI - Selective enhancement of glycolytic activity by incubation of yeast cells in sugars and polyols. PMID- 4302126 TI - [Electrolyte metabolism in central nervous system diseases of children. 3. Electrolyte metabolism in cerebral palsy]. PMID- 4302128 TI - The value of radiation therapy for pituitary and parapituitary tumours. PMID- 4302129 TI - Arrhenoblastoma of the ovary in an adolescent. PMID- 4302130 TI - The mechanism of supersensitivity to norepinephrine induced by cocaine in rat isolated vas deferens. PMID- 4302131 TI - DOPA-decarboxylase activity in sciatic nerves of the rat after constriction. PMID- 4302132 TI - Platelet lipids. II. In vitro incorporation of 1-14-C palmitic acid into lipid fractions of rabbit platelets. PMID- 4302133 TI - Depression of spinal motoneurones by noradrenaline, 5-hydroxytryptamine and histamine. PMID- 4302134 TI - Mitochondrial enzyme activity in "senescent" and virus-transformed human fibroblasts. PMID- 4302135 TI - Evaluation of the increased risk of gastrointestinal bleeding following intracranial surgery in patients receiving high steroid dosages in the immediate postoperative period. PMID- 4302136 TI - Nonchromaffin paraganglioma of the orbit. PMID- 4302137 TI - Relationship of route of inoculation and nature of toxin preparation to bioassay of Clostridium perfringens alpha-toxin in mice. AB - The toxicity of Clostridium perfringens was determined in mice utilizing three different routes of inoculation. There was marked variation in the minimum lethal dose with the different routes; the largest amount was required for the intracutaneous route, less for the intravenous route, and least with the intraperitoneal route. The relationship of toxicity to the lecithinase content of different toxin preparations was assayed. It was found that the toxicity of toxin preparations in different states of purification was not correlated with their lecithinase content. PMID- 4302139 TI - Cytochrome C552 in Agrobacterium tumefaciens. PMID- 4302138 TI - Purification and properties of cytochrome c-553 and cytochrome B-560 from Tetrahymena pyriformis. PMID- 4302140 TI - Multiplication in and transmission by Aedes aegypti of vesicular stomatitis virus. PMID- 4302142 TI - A program of resocialization for a long-term regressed schizophrenic patient. PMID- 4302143 TI - A rational approach to short-term counseling. PMID- 4302141 TI - Treatment drop-outs and the role of the crisis therapist. PMID- 4302144 TI - Planning playgrounds for the handicapped. PMID- 4302146 TI - Movigenic intervention: an expanded dimension. PMID- 4302145 TI - Nursing apparel and psychiatric patients: a comparison of uniforms and street clothes. PMID- 4302147 TI - International trends. PMID- 4302148 TI - The "generic equivalency" game. PMID- 4302149 TI - [Incidence of subclinical and latent infections of cytomegalovirus in a nursery during 1962-67]. PMID- 4302150 TI - Facial myokymia. PMID- 4302151 TI - Infection of adult mouse macrophages in vitro with cytomegalovirus. PMID- 4302152 TI - Flow responses to angiotensin in innervated and denervated kidneys. PMID- 4302153 TI - "Treatment-resistance" to idoxuridine in herpetic keratitis. PMID- 4302154 TI - Development of delayed dermal hypersensitivity in guinea pigs immunized with inactivated respiratory syncytial virus vaccines. PMID- 4302155 TI - Studies on Sendai virus cell fusion factor. PMID- 4302156 TI - Histochemical studies on phosphatase and arylsulphatase activity in human carious dentine. PMID- 4302157 TI - Live vaccines against influenza, adenoviruses, measles, and mumps. PMID- 4302158 TI - Physiologic and pathologic changes in acrylamide neuropathy. PMID- 4302159 TI - [Further contribution to the study of the antigenic structure of E. histolytica]. PMID- 4302160 TI - Effects of magnesium and calcium on neurones in the central nervous system. PMID- 4302161 TI - Alloxan and lactic acid dehydrogenase activity of the cornea. PMID- 4302162 TI - Orbital malignant non-chromaffin paraganglioma. Alveolar soft tissue sarcoma. PMID- 4302163 TI - [Brain tumors in man]. PMID- 4302164 TI - [Virogenic leukoencephalitis of man. On the etiology and pathogenesis of van Bogaert's subacute sclerosing leukoencephalitis]. PMID- 4302165 TI - [Effects of bilateral adrenalectomy on the cytology of the distal lobe of the pituitary of the green frog (Rana esculenta); attempt to identify the cells responsible for the secretion of corticotropic hormone]. PMID- 4302166 TI - [Relationship between structure and function in mitochondria of the rat adrenal cortex. Theory of vesiculization]. PMID- 4302167 TI - [Quantitative study of phasic phenomena of paradoxal sleep during and after its instrumental deprivation]. PMID- 4302168 TI - [Locus ceruleus, paradoxal sleep, and cerebral noradrenaline]. PMID- 4302169 TI - A fluorescent spot test for creatine kinase. PMID- 4302170 TI - [Simultaneous fluorometric determination of free cortisol and corticosterone in urine after thin-layer chromatography]. PMID- 4302171 TI - Perchloric acid interference in sodium and potassium determinations by atomic absorption. PMID- 4302172 TI - [Studies on the viral etiology of aphthosis. (II)]. PMID- 4302173 TI - Vascular responses to norepinephrine, angiotensin, vasopressin and serotonin. PMID- 4302174 TI - [Studies on carbohydrate metabolism in vitamin B6-deficient albino rat]. PMID- 4302175 TI - Localization of cell-bound penicillinase in Bacillus licheniformis. AB - When protoplasts are prepared from Bacillus licheniformis (strain 749/C, constitutive for penicillinase), approximately 60% of the cell-bound penicillinase is released. The remainder is retained by the protoplast and cannot be removed by washing. This release is specific, in that less than 7% of the cellular reduced nicotinamide adenine dinucleotide (NADH) dehydrogenase and alpha glucosidase is liberated by the treatment. The freed penicillinase is excluded from G-200 Sephadex, and it is partially sedimented with a force of 65,000 x g for 20 hr. It is probably attached to characteristic tubular and vesicular structures with single-layered membranes that are comparable to structures previously described in intact penicillinase-forming cells. The specific activity of the organelle is more than six times that of twice washed peripheral membrane; furthermore, about 8% of the protein of the structure is penicillinase. At substrate concentrations (benzylpenicillin) of about one-fifth the K(m) value, whole cells show a slight permeability restriction, although this does not occur in isolated particles and protoplasts. PMID- 4302176 TI - Activation of Hageman factor by collagen. AB - Purified acid-soluble and insoluble human collagen accelerated the clotting of plateletpoor plasma in silicone-treated tubes. The clot-promoting effect did not appear to be due to thromboplastic activity since the collagen preparations did not activate factor X in the presence of factor VII and calcium. Instead, collagen appeared to accelerate clotting by activating Hageman factor (factor XII) on the basis of the following findings: collagen increased the clot promoting activity of partially purified Hageman factor but exerted no further effect in the presence of kaolin, a known activator of Hageman factor; clot promoting eluates were obtained from collagen exposed to normal, hemophilic, or PTC-deficient plasma but not from collagen exposed to Hageman or PTA-deficient plasma. The collagen molecule itself appeared to be required for the clot promoting activity since digestion with collagenase or thermal denaturation at pH 2.5 (about 35 degrees C) resulted in very marked reduction in clot-promoting activity. Since thermal denaturation is associated with transformation of collagen structure from triple helical to random coil form, it is suggested that the native form of collagen is essential for the ability to activate Hageman factor. Blockage of the free amino groups by treatment with nitrous acid or dinitrofluorobenzene only slightly reduced the clot-promoting activity of collagen. In contrast, since addition of cationic proteins to collagen markedly reduced pro-coagulant activity it is suggested that negatively charged sites on the collagen molecule are critical for Hageman factor activation. This suggestion is supported by the finding that pepsin treatment of collagen, which removes the predominantly negatively charged telopeptides, results in significant decrease in coagulant activity. Esterification of collagen, which neutralizes 80-90% of the free carboxyl groups, reduced coagulant activity by over 90% and it is suggested that the free carboxyl groups of glutamic and aspartic acids provide the negatively charged sites critical for Hageman factor activation. PMID- 4302177 TI - Degradation of collagen by a human granulocyte collagenolytic system. AB - This report suggests a mechanism for collagen degradation mediated by human granulocytic leukocytes. A specific collagenase, which is extractable from human granulocytes, has been partially purified by DEAE chromatography. This collagenolytic enzyme is operative at physiological pH and is inhibited by EDTA, cysteine, and reduced glutathione but not by human serum. The enzyme cleaves the collagen molecule into two specific products, without loss of helical conformation. Electron micrographs of segment long spacing aggregates indicate that the cleavage occurs one-quarter of the length from the carboxy terminal end of the molecule. Experiments with crude extracts from granulocytes suggest that the specific products of granulocyte collagenase activity are then degraded by other proteases present in the human granulocyte. PMID- 4302178 TI - Incorporation of orthophosphate-32P into erythrocyte phospholipids in normal subjects and in patients with hereditary spherocytosis. AB - The in vitro incorporation of inorganic (32)P into erythrocyte phospholipids has been studied in normal subjects and in splenectomized patients with hereditary spherocytosis (HS). Phosphatidic acid (PA) was the only lipid measurably labeled in both kinds of cells. The actual turnover rate of PA phosphate was determined by simultaneously isolating inorganic phosphate (P(i)) and adenosine triphosphate (ATP) and determining their specific activities. This turnover is very small: 1.3 mumoles P/liter of erythrocytes per hr in normal cells and 4.0 mumoles P in HS erythrocytes when either ATP or cellular P(i) is considered the immediate precursor. This value represents less than 0.1% of the total membrane lipid phosphate. Incorporation of added (32)P(i) into the other phosphatides, including phosphatidyl serine, was essentially zero in both kinds of cells. The effects of stimulation and inhibition of active cation transport, metabolic depletion, and extracellular phosphate concentration on both the degree of labeling and the actual turnover of PA phosphate were studied. In any given experiment, the degree of labeling of PA depended on the specific activities of the other intracellular phosphates (P(i) and ATP). The actual turnover rate of PA phosphate, however, did not vary with active transport or metabolic depletion. The greater turnover of PA phosphate in HS erythrocytes may be due to the somewhat younger age of these cells. The results suggest that the very low turnover of PA phosphate in erythrocytes is mediated by nonspecific enzyme reactions, and that it is quantitatively insignificant in both normal and HS erythrocytes. The results also emphasize the importance of measuring intracellular phosphate precursors in any study evaluating cellular phospholipid turnover from added (32)P(i). PMID- 4302179 TI - Studies on collagenase from rheumatoid synovium in tissue culture. AB - Fragments of synovium from patients with rheumatoid arthritis survive in defined tissue culture medium in the absence of added serum and, after 3-4 days, release into the medium enzyme capable of degrading undenatured collagen. Maximal activity is observed at pH 7-9 but the enzyme is inactive at pH 5. At temperatures of 20 degrees and 27 degrees C, collagen molecules in solution are cleaved into 3/4 and 1/4 length fragments with minimal loss of negative optical rotation, but with loss in specific viscosity of approximately 60%. Above 30 degrees C the fragments begin to denature and denaturation is complete at 37 degrees C. If the enzyme is not inhibited at this stage the large fragments are broken down further to polypeptides of low molecular weight. Reconstituted collagen fibrils and native fibers at 37 degrees C are cleaved to the low molecular weight fragments, although the fibrils are resistant to breakdown at lower temperatures (20 degrees -27 degrees C). It is proposed that the production of such an enzyme by inflamed and proliferating rheumatoid synovium may be responsible for some of the destruction of collagenous structures that accompanies rheumatoid arthritis. PMID- 4302181 TI - Effect of heat treatment and storage temperature on phosphatase reactivation in butter. PMID- 4302182 TI - Strain MC29 avian leukosis virus: immunologic relationships to other avian tumor viruses. PMID- 4302180 TI - Radioimmunoassay of ACTH in plasma. AB - Techniques are described in detail for a radioimmunoassay of plasma adrenocorticotropin (ACTH) that is capable of detecting hormone in unextracted normal human plasma at 1:5 dilution under the conditions described. The sensitivity of the assay is at the level of 1 mumug/ml (equivalent to 0.014 mU/100 ml). In normal subjects ACTH concentrations averaged 22 mumug/ml (equivalent to 0.308 mU/100 ml) plasma at 8-10 a.m. In a smaller group the concentrations averaged 9.6 mumug/ml (equivalent to 0.134 mU/100 ml) at 10-11 p.m. Although a circadian rhythm in normal subjects was not always well marked throughout the daytime hours, plasma ACTH usually fell to its lowest value in the late evening. In hospital patients who were not acutely ill, concentrations were infrequently above 100 mumug/ml in the morning and usually fell to significantly lower levels in the late evening. Severely ill hospital patients occasionally exhibited a.m. concentrations above 200 mumug/ml. In a group of subjects showing frequent spiking of plasma 17-OHCS concentrations throughout the day parallel spiking of plasma ACTH as well was generally observed.Metyrapone produced marked increases in plasma ACTH within 24 hr in all cases and generally within 3-6 hr except when started late in the day. Dexamethasone brought about a persistent reduction in plasma ACTH in a patient under continued treatment with metyrapone.Hypoglycemia, electroshock, surgery under general anesthesia, histalog and vasopressin administration were usually followed by significant increases in plasma ACTH concentration. Prior administration of dexamethasone blocked the response to hypoglycemia. Marked elevations in plasma ACTH were observed in patients with adrenal insufficiency off steroid therapy, in Cushing's disease after adrenalectomy even in the presence of persistent hypercortisolemia, and in some untreated patients with Cushing's disease. Umbilical cord blood contained higher plasma ACTH concentrations than maternal blood at delivery in seven of eight cases. After suppression of ACTH secretion by dexamethasone or cortisol. ACTH disappeared from plasma with half-times ranging from 22 min to 30 min in three cases studied. PMID- 4302183 TI - [Formation of poly ADP-ribose from NAD by nuclear enzyme preparations]. PMID- 4302184 TI - Reduction of rapid-eye-movement sleep after electroconvulsions--an experiment in cats on the mode of action of electroconvulsive treatment. PMID- 4302185 TI - Enhancement of infectivity of murine cytomegalovirus in vitro by centrifugal inoculation. AB - Centrifugation of murine cytomegalovirus inocula from a variety of sources onto secondary mouse embryo cell monolayers at 1,900 x g for 30 min regularly revealed 10- to 100-fold more infectious virus than could be found in the same materials using standard inoculation methods. Virus demonstrable only by centrifugation was present throughout the entire growth cycle in a constant proportion to virus measured without centrifugation. Extracellular growth curves of both populations revealed an 18- to 21-hr latent period, followed by a long-linear increase over the next 12 hr; final yield was 30 plaque-forming units (PFU) per cell. Centrifugation of cells prior to inoculation or after standard adsorption and removal of inoculum failed to result in any significant change in measured virus titer. However, even after 4-hr adsorption, the supernatant inoculum could be transferred and centrifuged onto a fresh monolayer resulting in the same increment of measurable virus. Neutralizing antibody and interferon were equally efficacious against 100 PFU of virus as defined by either method. Thus, this newly identified population of cytomegalo-virus represents the vast majority of potentially infectious units and appears to differ solely in ease of adsorption onto cell monolayers. PMID- 4302186 TI - Replication of mengovirus in HeLa cells preinfected with nonreplicating poliovirus. AB - The replication of mengovirus in HeLa cells preinfected with poliovirus in the presence of 10(-3) M guanidine was investigated. Although host cell protein synthesis is inhibited by the presence of nonreplicating poliovirus, it is found that mengovirus ribonucleic acid (RNA) and protein synthesis proceed normally under the same conditions. Furthermore, no effects on mengovirus growth by poliovirus can be detected either when Mengo protein synthesis is interrupted by Acti-Dione or when its RNA synthesis is reduced by incubation at 28 C. It is suggested that the poliovirus inhibitory factor may be able to distinguish between an RNA element required in the protein-synthesizing apparatus of the host cell and a comparable element in that of the heterologous virus. PMID- 4302188 TI - Chromosomal aberrations and cloning efficiency in adenovirus type 12-infected hamster cells. AB - The fate of hamster cells, abortively infected with adenovirus type 12, has been studied by correlation of chromosomal aberrations with induction of T antigens and cloning efficiency. The incidence of chromosomal changes paralleled to some extent the T antigen formation, but was inversely related to the cloning efficiency of the cells. At an input multiplicity of 100, within 24 hr after infection, nearly all of the cells or metaphases revealed the presence of T antigens and chromosomal lesions, respectively, but no clones of cells were obtained. Inhibition of cellular deoxyribonucleic acid synthesis was not noted during this period. Increasing doses of ultraviolet irradiation reduced, successively, the capacity of the virus to induce chromosomal aberrations and correspondingly improved cloning efficiency of the exposed cells. It is concluded that most, if not all, cells revealing chromosomal lesions 24 hr after infection fail to enter further mitoses. PMID- 4302187 TI - Antiviral activity of polyacrylic and polymethacrylic acids. I. Mode of action in vitro. AB - Polyacrylic acid (PAA) and polymethacrylic acid (PMAA) were investigated for their antiviral properties in tissue culture. Compared to other related polyanions, as dextran sulfate, polystyrene sulfonate, polyvinyl sulfate, and polyphloroglucinol phosphate, PAA and PMAA were found to be significantly more antivirally active and less cytotoxic. PMAA added 24 hr prior to virus inoculation inhibited viral growth most efficiently but it was still effective when added 3 hr after infection. Neither a direct irreversible action on the virus nor inhibition of virus penetration into the cell could explain the antiviral activity of PMAA. PMAA inhibited the adsorption of the virus to the host cell and suppressed the one-cycle viral synthesis in tissue cultures inoculated with infectious RNA. PMID- 4302189 TI - Persistence of the viral genome in adenovirus type 12-infected hamster cells. AB - Induction of T antigen by adenovirus type 12 was studied in growing and growth inhibited cultures of the Nil-2 line of Syrian hamster cells. At a viral input multiplicity of 10, neoantigen was present in 100% of the cells by 24 hr. T antigen gradually disappeared in descendants of these cells so that 2 weeks after infection only 1% gave specific immunofluorescence. When cellular replication was prevented by addition of fluorodeoxyuridine, T antigen persisted in all cells for the 2-week period. Upon infection of growing cultures with purified (3)H-labeled adenovirus type 12 and autoradiographic analysis of the cells at various times thereafter, a gradual reduction in labeled nuclear loci was noted which paralleled the decrease in T antigen-containing cells. In nongrowing cultures, no change in labeled loci was noted. Correlation of T antigen and labeled loci revealed that fluorescent cells contained, on the average, about 10 times more silver grains than nonfluorescent cells. All of 92 preselected fluorescent cells showed labeled loci, whereas, of 100 nonfluorescent cells, 18 were free of silver grains. The implications of these findings are discussed. PMID- 4302190 TI - Use of zonal ultracentrifuge systems for biophysical studies of rhinoviruses. AB - This paper reports the use of zonal ultracentrifuge techniques to conduct biophysical studies of rhinoviruses grown with WI-38 cells. Good clean-out of infectivity from rhinovirus harvests was obtained with the continuous-flow B-V and B-IX rotors. Use of the B-V rotor resulted in the successful concentration of rhinovirus infectivity and antigenicity. Additional purification was achieved by the combined use of continuous-flow centrifugation and isopycnic banding procedures. Two particle sizes were found to be associated with the virus infected cell harvests. The infectious 22-nm particle banded in density ranges of 1.38 to 1.40 g/cm(3) in CsCl and 1.26 to 1.27 g/cm(3) in potassium citrate. The 8.0 nm capsomere was composed of 2.0 nm subunits and banded with a density of protein at 1.28 g/cm(3) in CsCl. Equivalent sedimentation coefficients of 155 or 185, depending on particle density in sucrose, were calculated from rate zonal experiments by use of the B-IV zonal rotor. PMID- 4302192 TI - Stabilization of enveloped viruses by dimethyl sulfoxide. PMID- 4302191 TI - Early step in Sendai virus-mediated rescue of Rous sarcoma virus from virogenic mammalian cells. PMID- 4302193 TI - Spin-labelled haemoglobin and the haem-haem interaction. PMID- 4302194 TI - Recent developments in pathophysiologic studies of the renin-angiotensin system. PMID- 4302195 TI - Hypertension and unilateral hydronephrosis. PMID- 4302196 TI - Importance of the bursa of fabricius in resistance to disease. 1. Resistance to certain virus diseases. PMID- 4302197 TI - [A particular complement fixation reaction applied to the study of tumors]. PMID- 4302198 TI - [Intensive program for the control of tuberculosis in a selected area]. PMID- 4302199 TI - Zoonoses in Britain: some present and potential hazards to man. Primate diseases. PMID- 4302200 TI - [On tumor RNA as an agent of malignant degeneration]. PMID- 4302201 TI - [Incidence of tumors in mice after the administration of syngenous tissue culture containing incomplete Rous virus]. PMID- 4302202 TI - ["Immunochemical endgrouping" with Helix agglutinins of ascites tumor cells. Comparison with the blood cells of animals]. PMID- 4302203 TI - [On 4 cases of the auricule-temporal syndrome (Frey's syndrome)]. PMID- 4302204 TI - [Experience of the precipitation reaction for the practical diagnosis of infection of fowls with the viruses of infectious laryngotracheitis and infectious bronchitis as well as with CELO virus]. PMID- 4302205 TI - [Multiplication of Aujeszky's virus in the spinal ganglia of the rabbit]. PMID- 4302207 TI - [Borders of lung segments and lamellar atelectasis in children]. PMID- 4302206 TI - [On the histoenzymological characteristics of hydrolytic enzymes in arteries in beginning arteriosclerosis]. PMID- 4302208 TI - [Effects of acute alcoholic intoxication on the distribution and activity of succinate dehydrogenase and cytochrome oxidase in the liver of the rat]. PMID- 4302209 TI - [Nonspecific phosphatases and their role in the morpho- and histogenesis of skeletal tumors]. PMID- 4302210 TI - [Quantitative evaluation of cytochrome oxidase activity (histochemical study)]. PMID- 4302211 TI - Arteriography in the diagnosis of liver tumours. PMID- 4302212 TI - [Diagnosis and therapy of islet cell adenomas]. PMID- 4302213 TI - [Therapy of Cushing's syndrome]. PMID- 4302214 TI - [Contribution on the clinical picture of the Verner-Morrison syndrome]. PMID- 4302215 TI - [Determination of elapsed time of the syringe injection by means of enzyme histochemical method]. PMID- 4302216 TI - [Mouth diseases caused by herpes simplex virus]. PMID- 4302217 TI - [Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa]. PMID- 4302218 TI - Fibroblastoid transformation of malignant myeloblasts in vitro. PMID- 4302219 TI - [Parotid metastasis of a paraganglioma jugulare-tympanicum]. PMID- 4302221 TI - [Inhibition of lactate dehydrogenase by nicotinamide adenine dinucleotide]. PMID- 4302220 TI - [On a component of the mixture of brain gangliosides, which is transferred to the Tay-Sachs ganglioside under the influence of neuraminidase]. PMID- 4302222 TI - [Kinetic studies on mitochondrial NADH-semidehydroascorbate-oxidoreductase (EC 1.6.5.4) in rat liver]. PMID- 4302223 TI - Inositol phosphates obtained from a phosphatido-peptide fraction of pig aorta. PMID- 4302224 TI - Studies on polypeptides. XLI. The synthesis of [5-valine, 6-beta-(pyrazolyl-3) alanine]-angiotensin II, a potent hypertensive peptide. PMID- 4302225 TI - Serological diagnosis of amoebiasis by immunofluorescence. AB - A positive serological diagnosis of amoebiasis could be made by immunofluorescence in 66 of 78 established cases, taking a serum titre of 16 or higher as diagnostic: at this level there were no false positives among 94 control sera. The test is simple and may be carried out on amoebic smears stored for several months in 2-octanol. The serological activity is largely confined to the IgG immunoglobulin fraction and is specific for Entamoeba histolytica; cross reactions were not detected with other protozoa. Gel diffusion serological analysis permitted a positive diagnosis of amoebiasis in 60 of the 78 cases, and, combining this with the immunofluorescence test, raised the diagnostic score to 71 cases. PMID- 4302226 TI - [Studies on the effect of 2-mercaptoethanol on the antisera against Japanese encephalitis virus. 5. Fractionation of swine sera by sephadex G-200 gel filtration]. PMID- 4302227 TI - [Effects of gentamycin and other antibiotics on Pseudomonas pyocyanea]. PMID- 4302228 TI - Effects of testosterone on adenosine triphosphate and nicotinamide adenine dinucleotide levels, and on nicotinamide mononucleotide adenylytransfersee activity, in the ventral prostate of castrated rats. PMID- 4302229 TI - The relationship between the pH-induced spectral change in ferriprotoheme and the substrate-induced spectral change of the hepatic microsomal mixed-function oxidase. PMID- 4302230 TI - [Experimental tumors of the central nervous system]. PMID- 4302231 TI - [Enzyme histochemistry of experimental tumors of the central nervous system]. PMID- 4302232 TI - [Aspects of the development of renal complications in pregnancy]. PMID- 4302233 TI - [Duodenal migraine]. PMID- 4302234 TI - [Child abuse]. PMID- 4302235 TI - [On the prognosis of Paget's disease of the female breast]. PMID- 4302236 TI - [On the problem of overbridging defects of the peripheral nerves]. PMID- 4302237 TI - [Pharmacokinetics of antitubercular agents]. PMID- 4302238 TI - [Frequency of side-effects of tuberulostatics and its relation to the applied combination]. PMID- 4302239 TI - Effects of transplanted pituitary glands from non-arteriosclerotic virgin and arteriosclerotic breeder donors to hypophysectomized rats. PMID- 4302240 TI - Structure-activity relationships of the adrenocorticotropins and melanotropins: the synthetic approach. PMID- 4302241 TI - Aerosol bronchography. A preliminary report. PMID- 4302242 TI - The variable fate of oily contrast media after lymphography compared with residues in other sites. PMID- 4302244 TI - Roentgenographic abnormalities in phenotypic females with gonadal dysgenesis. A comparison of chromatin positive patients and chromatin negative patients. PMID- 4302243 TI - Hepatic oil embolization following lymphangiography in a child with neuroblastoma. PMID- 4302245 TI - [The effect of vasoactive polypeptides on bronchial muscle and lung circulation]. PMID- 4302246 TI - Antibodies to enzymatic breakdown products of yeast tRNA. PMID- 4302247 TI - [Synthesis of peptides and peptide acting substances]. PMID- 4302248 TI - [On the different behavior, in some human products of secretion and of excretion, of factors neutralizing measles virus and poliomyelitis virus]. PMID- 4302249 TI - Dwarfism, oligophrenia and degeneration of the elastic tissue in skin and cornea. A new syndrome? PMID- 4302250 TI - [The lipids of human placenta during pregnancy. I. Quantitative determination of phosphatides by 2-dimensional thin layer chromatography]. PMID- 4302251 TI - Comparative studies on K -p-nitrophenylphosphatase, K -acylphosphatase and (Na + K)adenosinetriphosphatase in synaptosomes of rat brain. PMID- 4302252 TI - [Interactions between polypeptides and catecholamines]. PMID- 4302253 TI - The delayed effect of ACTH administration on the plasma corticoid level of normal elderly persons and patients with chronic brain syndrome. PMID- 4302254 TI - Infectious bovine rhinotracheitis: clinical review, immunity, and control. PMID- 4302255 TI - Bovine myxovirus parainfluenza-3 and its role in bovine respiratory disease. PMID- 4302256 TI - Lipid composition of chloroplasts isolated by aqueous and nonaqueous techniques. AB - Chloroplasts isolated from tobacco leaves in 0.5 M sucrose solution (the 1000 g pellet) contained 83% of the total cellular monogalactosyl diglyceride, 88% of the digalactosyl diglyceride, 76% of the sulfolipid, and 74% of the phosphatidyl glycerol. Phosphatidyl inositol was concentrated in the 15,000 g pellet. Phosphatidyl choline and phosphatidyl ethanolamine were concentrated in the 15,000 g supernatant fraction. Chloroplasts isolated from tobacco leaves by a nonaqueous technique in hexane-carbon tetrachloride show a glycerolipid composition similar to that found in chloroplasts isolated in the aqueous system, even though some lipid, particularly monogalactosyl diglyceride, is extracted by the organic solvent during the process. PMID- 4302257 TI - Thin-layer chromatography of the phosphoinositides. AB - Thin-layer chromatography for the separation of mono-, di-, and triphosphoinositides (0.3-3 micro g total phosphorus) is described. PMID- 4302258 TI - Effect of diet, dietary regimens and strain differences on some enzyme activities in rat tissues. PMID- 4302259 TI - In vivo and in vitro studies of gluconeogenesis in meal-fed and nibbling rats. PMID- 4302260 TI - Serotonin infusion in rats with experimental renovascular hypertension. PMID- 4302261 TI - Toxicity of emetine to isolated embryonic chick-heart cells. PMID- 4302262 TI - Mechanism of flow improvement by the addition of fine particles to bulk solids. PMID- 4302263 TI - [Attempts to shorten the fracture healing time]. PMID- 4302264 TI - Reversion of properties in cells transformed by polyoma virus. PMID- 4302265 TI - Erythrocyte ATP: D-fructose-6-phosphate 1-phosphotransferase (phosphofructokinase) activity in children with normalG trisomic mosaic Down's syndrome and in normal and Down's syndrome controls. PMID- 4302267 TI - [Vitamin D3 determination in accordance with egg shell formation in the Japanese quail]. PMID- 4302268 TI - Electrodermal levels and fluctuations during normal sleep. PMID- 4302266 TI - Carbohydrate metabolism in cancer cells and the molecular correlation concept. PMID- 4302269 TI - [Tumors of small salivary glands]. PMID- 4302270 TI - [Palpation relief. An important symptom in breast cancer]. PMID- 4302271 TI - [On the question of ploidy of astrocytomas and glioblastomas multiforme (cytophotometric study of the content of DNA in the nuclei)]. PMID- 4302272 TI - [Immunologic study of surface antigen extracted with sodium deoxycholate from the whooping cough microbe]. PMID- 4302273 TI - [Inactivation of pharmacologically active peptides by hemolysate fractions]. PMID- 4302274 TI - Slipped upper femoral epiphysis. Clinical study on aetiology. PMID- 4302275 TI - Treatment of American cutaneous leishmaniasis with cycloguanil pamoate. PMID- 4302276 TI - Respiratory infections in the American tropics. PMID- 4302277 TI - Cholelithiasis in rabbits: effects of bile constituents and hormones on dissolution of gallstones. PMID- 4302278 TI - Immunodiffusion of bluetongue virus. PMID- 4302279 TI - Aberrant characteristics and virus-like particles of bovine mammary cell cultures. PMID- 4302281 TI - Localization of lecithinase activity in Clostridium perfringens. PMID- 4302282 TI - Photodynamic antiviral substance extracted from chlorella cells. PMID- 4302280 TI - Modified biochemical tests for characterization of L-phase variants of bacteria. AB - Biochemical capabilities of bacterial and L-phase organisms of 15 bacterial strains were examined by using a variety of modified routine diagnostic biochemical tests. The results demonstrated that 13 of the tests examined were suitable for use with L-phase variants, that L-phase variants and revertant bacterial phase organisms retained diagnostically significant capabilities of the respective bacterial or L-phase organisms from which they were derived, and that the 13 biochemical tests could be usefully employed to relate a given L-phase variant to a given bacterial phase organism, to distinguish L-phase variants of different species, and to aid in the identification of nonreverting L-phase variants. PMID- 4302283 TI - Survival of a picornavirus and its infectious ribonucleic acid after aerosolization. PMID- 4302284 TI - Viral depuration by assaying individual shellfish. AB - A study was carried out to further evaluate the practicability of viral depuration by assaying individual shellfish. The Northern quahaug and a strain of the type 1 attenuated poliovirus were used as the working model. Two types of depuration systems were employed: the small experimental tanks and a pilot-size tank with a capacity of approximately 24 bushels (836 liters) of shellfish. Volumes of the individual shellfish samples were found uniform throughout the experiments when a prior selection for the weight of the shellfish was made. There was also no significant difference in volumes of the individual samples during the course of depuration (24 to 96 hr). Under controlled hydrographic conditions, however, the uptake of virus in individual shellfish varied considerably. In general, the individual variability reached 10- to 100-fold. This wide variation would explain the variability of viral contents obtained in pooled samples during depuration as reported previously. During a later phase of depuration, although a great majority of shellfish were free of the virus, a few still harbored minimal amounts of contaminants. The presence of virus in some of the shellfish after various periods of depuration would, theoretically, be obscured by the pooling of the sampled shellfish. Further examination of the negative samples by assaying larger quantities than those routinely used revealed that a few still contained virus. To simulate naturally polluted shellfish as closely as technically possible, shellfish were polluted with minimal amounts of virus. The shellfish were cleansed more rapidly by the depuration process than were those polluted with more virus. Since the naturally polluted shellfish were shown to contain less virus than those studied in the laboratory, it is anticipated that the former type of shellfish may be cleansed more readily by this process within a reasonable period of time. Justification for a field trial of depuration in this country is presented. PMID- 4302285 TI - [Purification of human placental prolactin by selective precipitation with lead perchlorate]. PMID- 4302286 TI - [Action of thyroid hormones on the oxidoreduction state of respiratory coenzymes]. PMID- 4302287 TI - [Detection of enteroviruses in patients of the Rudolf-Virchow hospital before and following oral polio immunizations 1960 and 1962]. PMID- 4302288 TI - [The so-called lobular carcinoma of the breast. Pathological and clinical consequences]. PMID- 4302289 TI - [Problems of nerve suture]. PMID- 4302290 TI - Functional significance of the tubular agranular endoplasmic reticulum in the adrenocortical cells of albino rats. PMID- 4302291 TI - Effects of dibutyryl cyclic AMP on adrenal growth and steroidogenic capacity. PMID- 4302292 TI - Stimulation of progesterone release and estrous behavior by ACTH in ovariectomized rodents. PMID- 4302294 TI - Induction of hepatoma and systemic amyloidosis in mice by 4 (dimethylamino)azobenzene feeding. PMID- 4302293 TI - Steroid hormone transformations by endocrine organs from pregnant mammals. 3. Biosynthesis and metabolism of progesterone by the Mare placenta in vitro. PMID- 4302295 TI - The characterization and thin-layer chromatographic quantitation of the human metabolite of 7-deoxy-7(S)chlorolincomycin (U-21,251 F). PMID- 4302297 TI - Lymphocytosis and histamine sensitization of mice by fractions from Bordetella pertussis. AB - Administration of Bordetella pertussis cell extracts induced in mice hypersensitivity to histamine, as well as pronounced leukocytosis and hypoglycemia. The leukocytosis was mainly caused by an increase in the small lymphocytes in the circulating blood, and it was most pronounced 3 to 4 days after injection of B. pertussis extracts. Rabbit antimouse lymphocyte serum produced a decrease in the lymphocyte count in normal mice, as well as in mice treated with B. pertussis extracts. This depression in lymphocytes was observed whether the antilymphocyte serum was given 1 day or 2 days after the administration of B. pertussis extracts. The increased histamine sensitivity and hypoglycemia of mice treated with B. pertussis extract were not affected by treatment with antilymphocyte serum, although a marked lymphopenia was present. These observations indicate that the three phenomena observed in pertussis treated mice are independent of each other. PMID- 4302296 TI - Comparative intermediary metabolism of vegetative cells and microcysts of Myxococcus xanthus. AB - Crude extracts of both vegetative cells and glycerol-induced microcysts of Myxococcus xanthus contained the following enzyme activities: phosphofructokinase, phosphoglucoisomerase, fructose-1,6-diphosphatase, fructosediphosphate aldolase, glyceraldehyde-3-phosphate dehydrogenase, phosphopyruvate carboxylase, citrate synthase, isocitrate dehydrogenase, alpha ketoglutarate dehydrogenase, succinate dehydrogenase, malate dehydrogenase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, phosphoglucomutase, and uridine diphosphate glucose pyrophosphorylase. With the exception of isocitrate dehydrogenase, which was present at a fivefold higher concentration in microcysts, all activities in extracts from both types of cells were essentially equal. Hexokinase and pyruvate kinase could not be detected in extracts from either type of cell. Microcysts metabolized acetate at a lower rate than did vegetative cells. Most of this decrease was reflected in a substantial decrease in ability of microcysts to oxidize acetate to CO(2). In addition, microcysts and vegetative cells showed a different distribution of (14)C-label from incorporated acetate. PMID- 4302298 TI - Respiratory components of Aspergillus niger mitochondria. AB - The respiratory components of tightly coupled mitochondria from the filamentous fungus Aspergillus niger were studied. Cytochromes a + a(3), b, and c + c(1) were identified by difference spectra. The cytochrome spectra were qualitatively similar to yeast and rat liver mitochondria. The mitochondria contained, per gram of protein, an average of 2.9 and 7.0 mumoles of ubiquinone and nicotinamide adenine dinucleotide, respectively. PMID- 4302299 TI - Molar growth yields as evidence for oxidative phosphorylation in Streptococcus faecalis strain 10Cl. AB - During the aerobic growth of Streptococcus faecalis strain 10C1, with limiting levels of glucose as the substrate, a molar growth yield (Y) of 58.2 g (dry weight) per mole of glucose was obtained. Under these conditions of growth, glucose was dissimilated primarily to acetate and CO(2). The incorporation of (14)C-glucose into cell material was no greater under aerobic conditions than during anaerobic growth. Assuming an adenosine triphosphate coefficient of 10.5, the aerobic Y cannot be explained solely on the basis of substrate phosphorylation and would appear to substantiate previous enzymatic evidence for oxidative phosphorylation in this cytochromeless species. With mannitol as the substrate, an aerobic Y of 64.6 was obtained. Extracts of mannitol-grown cells contained a nicotinamide adenine dinucleotide (NAD)-linked mannitol-1-phosphate (M-1-P) dehydrogenase. The difference in aerobic Y values with mannitol and glucose as substrates would indicate that the in vivo P/O ratio from the oxidation of reduced NAD generated by the oxidation of M-1-P approximates 0.6. The Y values with pyruvate and glycerol as substrates under aerobic conditions were 15.5 and 24.7, respectively. PMID- 4302300 TI - Cytology of spore formation in Clostridium perfringens. AB - The sequential morphological events in spore formation by Clostridium perfringens type D were observed in Ellner's medium where 80 to 100% of the cells formed spores. Gross structural changes were studied with the light microscope under phase-contrast, and in fixed cells by the use of both nigrosin and Giemsa preparations. Fine structure was examined with the electron microscope in both thin sections and frozen-etched preparations. During the first 3 hr of incubation, the original rod-shaped cells became ellipsoid to ovoid in shape; by 5 to 6 hr, subterminal spores had developed within these enlarged cells. The fine structural sequence was in most respects identical to that in other Bacillaceae, although some stages were illustrated with particular clarity. A unique feature was the development of a convoluted, membranous exosporium which adhered to the outer surface of the two coats and had an unusual fine structure resembling a rectangular array of subunits. PMID- 4302301 TI - [Phosphorylated polysaccharides in nature]. PMID- 4302302 TI - Distribution and fatty acid composition of phosphoglycerides in normal human brain. AB - A thin-layer chromatographic procedure for the isolation of tissue phospholipids and their subsequent analysis is described. The method has been applied to the determination of the fatty acids of phosphoglycerides in human brain from the early fetal stage to old age. The study shows changes in the distribution and fatty acid composition of each phosphoglyceride in normal brain, although they are quite small after early childhood. A lipid-specific fatty acid pattern for each of the four major phosphoglycerides was found. Besides this, the pronounced differences between fatty acids of the lipids from the cerebral cortex and from the adjacent white matter justify speaking of a tissue-specific fatty acid pattern for brain phosphoglycerides. The phospholipids of cerebral white matter contained more monoenoic acid but much less polyunsaturated fatty acid than those of cerebral cortex. The brain phosphoglycerides also showed an age-dependent fatty acid pattern. With increasing age the concentration of the fatty acids of the linoleate family diminished while that of the linolenate family increased. Brain inositol phosphoglycerides, the fatty acid composition of which has not been studied systematically before, were characterized by a large concentration of arachidonate which was nearly as high for white as for gray matter and showed only small changes with age. PMID- 4302303 TI - Comments on the action of quaternary ammonium compounds at the receptor site. PMID- 4302304 TI - Analysis of simian virus 40-induced transformation of hamster kidney tissue in vitro. V. Variability of virus recovery from cell clones inducible with mitomycin C and cell fusion. AB - Clones of simian virus 40-transformed hamster kidney cells from which infectious virus could be recovered and clones which did not yield virus by the overlay technique were subjected to chemical (mitomycin C) induction and to co cultivation and fusion studies with indicator cells. The results of these studies indicate that the complete viral genome is present in all clones tested but that considerable heterogeneity with respect to inducibility exists among the clones. It is suggested that differences either in the number of viral genomes per transformed cell or in the status of the viral genome in transformed cells exist among the various clones. Furthermore, the inducibility of the clones may be correlated with their malignant potential. PMID- 4302305 TI - [Autopsy case of primary malignant mixed tumors of the liver, with a review of the literature]. PMID- 4302306 TI - [Nephrotic syndrome--follow-up results of steroid therapy]. PMID- 4302307 TI - [Recent progress in synthetic ACTH--several basic problems]. PMID- 4302308 TI - [Have we made advances in the surgical treatment of bronchial carcinomas?]. PMID- 4302309 TI - Physicochemical characteristics of rubella antigens theta and iota. PMID- 4302310 TI - Individual variations in rate of skeletal maturation. PMID- 4302311 TI - Identification of plasma angiotensinase as aminopeptidase. PMID- 4302312 TI - Failure to induce scurvy by ascorbic acid depletion in a patient with Hurler's syndrome. PMID- 4302313 TI - Thermography as an investigative method. PMID- 4302314 TI - [Immunologic diagnosis of acute pulmonary disease]. PMID- 4302315 TI - Breakdown in maternal protection: infections. PMID- 4302316 TI - [Cerebral angiography by means of catheterization]. PMID- 4302317 TI - [Apropos of 13 benign tumors of the stomach]. PMID- 4302318 TI - [Gastric lipoma revealed by digestive tract hemorrhage]. PMID- 4302319 TI - [Comparative radiologic and anatomic studies of ulcerative colitis]. PMID- 4302320 TI - [The future of surgical patients with portacaval anastomosis (study of the long term resuls with 100 surgical patients between 1959 and 1964)]. PMID- 4302321 TI - [Disorders of water-electrolyte metabolism associated with decompensated cirrhosis. The danger of various therapeutic drugs]. PMID- 4302322 TI - [Diagnosis and treatment of idiopathic hemochromatosis]. PMID- 4302323 TI - [Osteoporosis and mastocytosis. Apropos of 2 cases]. PMID- 4302324 TI - [Lymphography and cancer of the penis]. PMID- 4302325 TI - [Clinical value of haptoglobin and seromucoid determination in Hodgkin's disease]. PMID- 4302326 TI - [Effect of sodium bicarbonate therapy with Vichy water on hiatal hernia and gastroesophageal reflux]. PMID- 4302327 TI - [Importance of selective arteriography in the diagnosis of hypoglycemic Langerhansian tumors. Apropos of 3 cases]. PMID- 4302329 TI - [Primary tuberculosis of the liver. Apropos of a case]. PMID- 4302328 TI - [Hypoglycemia induced by hypoglycemic sulfamides. 4 cases including of voluntary massive poisoning]. PMID- 4302330 TI - [Therapeutic effectiveness and clinical tolerance in children of a medication combining in the same preparation of a tetracycline base with lyophilized lactobacillus]. PMID- 4302331 TI - Synthetic beta 1-24-corticotropin stimulation of cortisol biosynthesis by rabbit adrenal tissue. PMID- 4302332 TI - Isolation of crystalline estriol-3-glucuronide from human pregnancy urine. PMID- 4302333 TI - [Level of reduced glutathion and some liver enzyme activities during simple alloxan and acido-ketotic diabetes in mice]. PMID- 4302334 TI - [On the cytochemistry and cytophysiology of autonomic neurons]. PMID- 4302336 TI - [Changes caused by x-rays in the chromosomes of cells of ascites tumor]. PMID- 4302335 TI - [Change in the activity of nonspecific phosphatases in the liver of several mammals by the administration of a carcinogen]. PMID- 4302337 TI - [Anti-beta 1-24 corticotropin antibodies]. PMID- 4302338 TI - [ACTH]. PMID- 4302339 TI - Cylindroma involving the paranasal sinuses. PMID- 4302340 TI - Vitamin K1-3H in man. Its intestinal absorption and transport in the thoracic duct lymph. PMID- 4302341 TI - [Chromosomal studies of trophoblastic tumor]. PMID- 4302342 TI - [Effect of 17 beta-estradiol on RNA polymerase of normal and cancerous hepatic cells]. PMID- 4302343 TI - Analysis of factors affecting lactic dehydrogenase subunit composition determinations. PMID- 4302344 TI - An analog model for acetylcholine release by motor nerve endings. PMID- 4302345 TI - [Chemotherapeutic activity and diffusion properties of the second series antituberculous preparations]. PMID- 4302346 TI - [Malignant degeneration of the stomach ulcer]. PMID- 4302347 TI - [Effect of ACTH on behavior of the acidophilic leukocytes and leukergia in peripheral blood of patients after cerebral apoplexy]. PMID- 4302348 TI - [Mechanisms of cell transformation by SV40 and polyoma virus. 1]. PMID- 4302349 TI - [Effect of angiotensin and nonadrenaline in pressor and non pressor doses on the urinary secretion of sodium in uncompensated cirrhotic patients]. PMID- 4302350 TI - [Renal transplantation, arterial hypertension and plasma renin levels in dogs]. PMID- 4302351 TI - [Para-influenza viruses]. PMID- 4302352 TI - Methodology and techniques in visual field studies. PMID- 4302353 TI - The effect of ochratoxin A on glycogen storage in the rat liver. PMID- 4302356 TI - [A contrast study of the maxillary sinuses with sergosin solutions]. PMID- 4302355 TI - Systematic radiologic approach for the diagnosis of temporal bone disease. PMID- 4302354 TI - Ophthalmological aspects of neuroblastomatosis: a study of 53 verified cases. PMID- 4302357 TI - [The nature of infectivity in Ehrlich ascites carcinoma cells infected by Sendai virus]. PMID- 4302358 TI - [Activity of succinate dehydrogenase in ascites cells of Ehrlich carcinoma infected by herpesvirus]. PMID- 4302359 TI - [Use of Ehrlich ascites carcinoma in working with para-influenza viruses]. PMID- 4302360 TI - [Serologic diagnosis of para-influenza infection in children ill with acute respiratory diseases]. PMID- 4302361 TI - [On the role of "latent" adenovirus in the occurrence of outbreaks of acute respiratory diseases]. PMID- 4302362 TI - [Embryos and embryonal tissue culture of Japanese quail as a possible "leukosis less" system for the production of vaccine and virologic studies]. PMID- 4302363 TI - [Irreversible inactivation of vaccinia and poliomyelitis viruses with homologous antibodies in the presence of cofactor]. PMID- 4302364 TI - [A study of the duration of persistence of viral antigen in the lymphoid organs of non-susceptible animals]. PMID- 4302365 TI - [Comparative study of the sensitivity of various cell cultures to herpes simplex virus]. PMID- 4302366 TI - [Use of the method of quantitative calculation of fluorescing cells in the study of the periods of absorption and permeability to para-influenza type 2 virus in sensitive cells]. PMID- 4302367 TI - The topographic and subcellular distribution of some cation-activated phosphohydrolases in rat brain. PMID- 4302368 TI - [The enzymatic activity of the blood in diagnosis of diseases of the liver and bile ducts]. PMID- 4302370 TI - Selection of therapy of glomus jugulare tumors. PMID- 4302369 TI - The cholinergic system in insect development. PMID- 4302371 TI - Glomus jugulare tumors. Long-term tumors. PMID- 4302372 TI - Jugular venography. PMID- 4302373 TI - Neuro-otologic tests and examination. PMID- 4302374 TI - Radiologic diagnosis of neuro-otological problems by conventional radiology. PMID- 4302375 TI - [A study of the conditions of the formation of interferon in a tissue culture of fibroblasts of chick embryo infected with Japanese encephalitis virus]. PMID- 4302376 TI - Action of various sympathomimetic amines on the isolated stripped vas deferens of the guinea-pig. AB - 1. The contractile potencies of some sympathomimetic amines and cholinergic drugs were studied in the isolated, stripped vas deferens of the guinea-pig.2. alpha Methylnoradrenaline, adrenaline and metaraminol produced the same relative maximal responses as noradrenaline, which served as reference drug; on the other hand, octopamine, dopamine and alpha-methyldopamine were much less active. Short term pretreatment of the animals with reserpine did not affect the maximal relative responses.3. Tyramine, alpha-methyl-m-tyramine and hordenine methiodide had little effect on the untreated preparation. In the presence of just threshold concentrations of noradrenaline, the relative maximal responses to tyramine and hordenine methiodide were markedly increased.4. The relative maximal response to carbachol was the same as that to noradrenaline, while that to DMPP was smaller. In contrast to carbachol, the action of DMPP was potentiated by pretreatment of the preparation with noradrenaline. PMID- 4302377 TI - The interaction between angiotensin and sympathetic vasoconstriction in the isolated artery of the rabbit ear. AB - 1. Infusions or injections of angiotensin into the isolated ear artery preparation of the rabbit produced only feeble vasoconstrictions and depressed the sensitivity of the preparation to sympathetic stimulation, tyramine and noradrenaline.2. The anti-sympathetic effect of angiotensin was not prevented or reversed by noradrenaline or cocaine.3. The vasoconstrictor response to angiotensin was usually markedly increased during sympathetic stimulation or other procedures which liberate endogenous noradrenaline (for example, infusion of tyramine), but not when the perfusion pressure was raised by increasing the flow rate or by infusing noradrenaline.4. The vasoconstrictor action of tyramine was also potentiated by sympathetic stimulation.5. The potentiation by sympathetic stimulation of the responses to angiotensin was prevented by reserpine, guanethidine and phentolamine in concentrations which abolished sympathetic vasoconstriction.6. It is suggested that angiotensin facilitates the release of endogenous noradrenaline and owes part of its vasoconstrictor activity to this property. PMID- 4302378 TI - The mobilization of free fatty acids from rabbit adipose tissue in situ. AB - 1. The epigastric adipose tissue of rabbits has been prepared so that the effects of close arterial injections and infusions on blood flow and release of free fatty acids (FFA) can be studied. The effects of pharmacologically active agents and hormone preparations have been investigated.2. Release of FFA was stimulated by synthetic adrenocorticotrophic hormone (ACTH), alpha and beta melanophore stimulating hormone (MSH), porcine growth hormone, glucagon, thyrotropic hormone (TSH) and luteotropic hormone (LTH). Single injections of fat-mobilizing agents produce a sustained rise in the release of FFA.3. Although pitressin caused release of FFA, synthetic vasopressin and oxytocin failed to do so. The FFA releasing activity of pitressin has therefore been attributed to a contaminant.4. Catecholamines were found not to stimulate release of FFA from this fat depot, but were found to increase plasma FFA when infused intravenously.5. Injections of acetylcholine, histamine, bradykinin, 5-hydroxytryptamine, synthetic arginine vasopressin, and lysine vasopressin, oxytocin, angiotensin and FSH did not stimulate release of FFA although marked effects on blood flow were produced.6. Injections of prostaglandin E(1) gave sustained increases in blood flow, and inhibited FFA release when stimulated by growth hormone.7. The mobilization of FFA is sometimes associated with an increased rate of blood flow. PMID- 4302379 TI - Effect of rabbit antibodies against angiotensin-II on the pressor response to angiotensin-II and renal hypertension in the rat. AB - 1. In the intact or nephrectomized rat, the pressor responses to synthetic angiotensin-II-amide, beta-angiotensin-II and native "rat angiotensin" could be inhibited by intravenous injection of rabbit serum containing antibodies against synthetic angiotensin-II-amide.2. The pressor responses to vasopressin or noradrenaline were not influenced by anti-angiotensin serum.3. A single injection of anti-angiotensin serum inhibited the pressor responses to angiotensin-II-amide for a period of 2.5 hr.4. Intravenous infusion or daily intraperitoneal injection of anti-angiotensin serum did not influence blood pressure levels in renal hypertensive rats. PMID- 4302380 TI - Non-specific inhibitory effects of morphine-like drugs on transmission in the superior cervical ganglion and guinea-pig isolated ileum. PMID- 4302381 TI - Neurophysiological methods in anaesthesia research. PMID- 4302382 TI - Anaesthetic action of magnesium ions. PMID- 4302383 TI - Nuclear magnetic resonance studies of junctional transmitter-receptor interactions. PMID- 4302384 TI - Suppression studies in affective disorders. PMID- 4302385 TI - Enzymic flux rates in vivo through the Embden-Meyerhof pathway and the nucleotides of the mouse liver. PMID- 4302386 TI - Oxygen consumption in adult Echinostoma revolutum. PMID- 4302387 TI - Carbohydrate utilization by Entamoeba histolytica. PMID- 4302388 TI - Histochemical changes in rat adrenal cortex influenced by thioacetamide and ACTH. PMID- 4302389 TI - Mode of action of rat liver phosphodiesterase on a polymer of phosphoribosyl adenosine monophosphate and related compounds. PMID- 4302390 TI - Deacylated transfer ribonucleic acid as a factor for peptide chain initiation in rabbit reticulocyte systems. PMID- 4302391 TI - Biosynthesis of branched chain deoxysugars. IV. Isolation of cytidine diphosphate 6-deoxy-3-C-methyl-2-O-methyl-4-O-(O-methyl-glycolyl)-L-aldohexopyranoside from Azotobacter vinelandii. PMID- 4302392 TI - Glutamine phosphoribosylpyrophosphate amidotransferase. Purification, substructure, amino acid composition, and absorption spectra. PMID- 4302393 TI - The accumulation of glucose 6-phosphate from glucose and its effect in an Escherichia coli mutant lacking phosphoglucose isomerase and glucose 6-phosphate dehydrogenase. PMID- 4302394 TI - [Study on the promotion of longitudinal bone growth, with special reference to enzyme activities in the epiphyseal growth plate]. PMID- 4302395 TI - Studies in fluorescence histochemistry. V. The influence of trace metals on the fluorescence of periodate-oxidized mucosubstance salicylhydrazones. PMID- 4302396 TI - Role of the vagus nerve in the control of the concentration of angiotensin II in the circulation. PMID- 4302397 TI - Synthesis of functional proteins in x-irradiated mammalian cells. PMID- 4302398 TI - Behaviour of infectious RNA from four different viruses in continuously subcultured Aedes aegypti mosquito embryo cells. PMID- 4302399 TI - Viruses isolated from sheep. PMID- 4302401 TI - Mixed mesodermal tumour of the uterus occurring after radiotherapy. PMID- 4302400 TI - Skeletal renewal and metabolic bone disease. PMID- 4302402 TI - Dysmorphogenesis: the role of infection. PMID- 4302403 TI - [On a case of histiocytoma of the vulva with unusual trabecula-like structure]. PMID- 4302404 TI - [Case of primary liver cancer with a compressed shadow on the radiogram]. PMID- 4302405 TI - [Statistical observations of cystosarcoma phyllodes]. PMID- 4302406 TI - [Study on the risk of pneumoconiosis through artificial abrasives, in a polishing wheel factory]. PMID- 4302407 TI - [Hereditary multiple glomus tumors (Barre-Masson's disease)]. PMID- 4302408 TI - [Influence of the believe in magics on the form of mental disorders in patients from southern Italy]. PMID- 4302409 TI - Studies of wheat-embryo ribosomal RNA. I. PMID- 4302410 TI - Effect of gamma-radiation on aqueous solutions of DNA's of different base composition. PMID- 4302411 TI - Enhancement by 2,4-dichlorophenoxyacetic acid of chromatin RNA polymerase in soybean hypocotyl tissue. PMID- 4302412 TI - Increased cardiovascular reactivity caused by depletion of endogenous renin in dogs. PMID- 4302413 TI - [The lipolytic action of ACTH. 3. Comparison of the lipolytic and corticoadrenal response to extrative and synthetic corticotropin in obese children]. PMID- 4302414 TI - [Indications, possibilities and limitations of medical therapy of regional ileitis (Crohn's disease)]. PMID- 4302415 TI - [Humoral factors and motility of the intestine. I. Kinino-hormones]. PMID- 4302416 TI - [Cortisolemia after corticotropin in various physiopathological situations]. PMID- 4302417 TI - Conflicting hypotheses on experimental silicotic fibrogenesis: new experimental data. PMID- 4302418 TI - Role of connective tissues in large pulmonary airways. PMID- 4302419 TI - Some features of the central co-ordination of a fast movement in the crayfish. PMID- 4302420 TI - Amechanical model of the mammalian muscle spindle. PMID- 4302421 TI - [Metastases in 717 consecutive autopsies for malignant tumors]. PMID- 4302422 TI - [Apropos of 274 primary malignant tumors of the vulva treated by the Fondation Curie from 1945 to 1965. Therapeutic results]. PMID- 4302423 TI - [Results and problems in functional diagnosis]. PMID- 4302424 TI - [The biologic effect of synthetic human corticotropine(alpha-h-ACTH) in man. (Preliminary report)]. PMID- 4302425 TI - [An unusual case of arrhenoblastoma]. PMID- 4302426 TI - [Relationship between recruiting responses and levels of awareness in cats. Analysis by a medical data processing computer]. PMID- 4302427 TI - [Studies on the metabolism of nicotinamide adenine dinucleotide (NAD) in the brain]. PMID- 4302428 TI - Mode of action of insulin in the regulation of protein biosynthesis in muscle. PMID- 4302429 TI - The actions of insulin and catabolic hormones on the plasma membrane of the fat cells. PMID- 4302430 TI - Neural control of anterior pituitary functions. PMID- 4302433 TI - [Myxovirus]. PMID- 4302432 TI - Iunes M: [Effect of angiotensin on the urinary secretion of sodium in normal persons]. PMID- 4302431 TI - Endocrine factors in the pathogenesis of plasma cell tumors. PMID- 4302434 TI - [Hepatitis syndrome]. PMID- 4302435 TI - [Precocious puberty]. PMID- 4302436 TI - [On the reactivity of skin arterioles in hypertension under the influence of histamine]. PMID- 4302437 TI - [Determination of blood serum cholesterol]. PMID- 4302438 TI - [Cerebral tumor and suspect death]. PMID- 4302439 TI - [3 cases of glomus jugulare tumor treated by radiotherapy]. PMID- 4302440 TI - Effects of calcium and magnesium on sympathetic transmission in human fallopian tube. PMID- 4302441 TI - [Study of hemagglutinin inhibiting antibodies of certain respiratory myxoviruses in a sample of the population of Riyad (Saudi Arabia)]. PMID- 4302442 TI - [Cytomorphological characteristics of phyllode tumors of the breast and its diagnostic singificance]. PMID- 4302443 TI - [Moot questions on the histogenesis of hormone-producing tumors of the ovaries]. PMID- 4302444 TI - [Abrikosov's tumor in the stomach]. PMID- 4302445 TI - Respiratory control in submitochondrial particles obtained by sonication. PMID- 4302446 TI - Lysolecithin inhibition of mitochondrial metabolism. PMID- 4302447 TI - The intramembrane location of alcohol anesthetics. PMID- 4302448 TI - [Virological aspects of an outbreak of poliomyelitis in Honduras]. PMID- 4302450 TI - [Maternal vitamin imbalances and embryonal malformations. 3. Effects of single deficiencies of vitamin B 2 or B 12 or folic acid]. PMID- 4302449 TI - [Phosphatase activity in various forms of keratinization]. PMID- 4302451 TI - [Clinical behavior of soft tissue sarcoma]. PMID- 4302452 TI - [Congenital intrahepatic bile duct cysts with calcinosis and malignant degenerations]. PMID- 4302453 TI - [Study of the relation between the concentration of ATP and NADH and the increased synthesis of porphyrins in the liver of white rats during experimentalporphyria]. PMID- 4302454 TI - [Effects of a monoanime oxidase inhibitor on sleep in rats]. PMID- 4302455 TI - [02 and CO2 partial pressures in experimental and human cancerous pleural and peritoneal effusions]. PMID- 4302456 TI - [Clinical presentation of erysipelas carcinomatosum]. PMID- 4302457 TI - [On the possible consequences of the diffusion of the virus after poliomyelitis vaccination with attenuated poliovirus vaccine]. PMID- 4302458 TI - [Studies on the transplacental transmission of antipoliomyelitis immunoglobulins]. PMID- 4302459 TI - [Biochemical changes in rabbit eyes caused by poisoning with trichlor-ethylene]. PMID- 4302460 TI - [On the reversibel biochemical changes in lens and retina of rabbit eyes due to carbon disulfide poisoning]. PMID- 4302461 TI - [Neuronitis vestibularis]. PMID- 4302462 TI - Preservation of glucose 6-phosphatase activity in formaldehyde-fixed fresh frozen sections. PMID- 4302463 TI - [Splenoganglionic amylosis and hydatid cyst of the liver. Antomoclinical case]. PMID- 4302466 TI - [Mechanism of cell transformation by SV40 and polyoma virus. 2]. PMID- 4302465 TI - [Serum protein bidning of ACTH. II. Studies using density-gradient centrifugation and H3-ACTH]. PMID- 4302464 TI - [Gastric secretion analysis in the Zollinger-Ellison syndrome]. PMID- 4302467 TI - [The diagnostic importance of meningeal branches of the internal carotid artery]. PMID- 4302468 TI - [Possibilities and limitations of lymphography using oily contrast media]. PMID- 4302469 TI - [Kinetic studies following intralymphatic administration of radioactive substances. Its significance for the diagnosis and therapy of malignant tumors]. PMID- 4302470 TI - [Lympho-lymphatic and lymphovenous shunt variations (demonstrated on an intrahepatic lipidol depositing following lymphography]. PMID- 4302471 TI - [Lymphographic findings in chronic pancreatitis]. PMID- 4302472 TI - Cytomegalovirus infection complicating open-heart surgery. PMID- 4302473 TI - [Properties of Vipera lebetina venom phosphodiesterase]. PMID- 4302474 TI - [Some peculiarities in the metabolic activity of thiamine monophosphate]. PMID- 4302475 TI - [The nature of macrophagic cell resistance to infection by viral nucleic acids]. PMID- 4302476 TI - [Cordiamin effect on the respiration and oxidative phosphorylation in the heart tissue of rabbits]. PMID- 4302478 TI - [Adrenergic mechanisms as basis of pharmacological agent action. I]. PMID- 4302477 TI - [On the adaptive changes in enzymatic constellations of lysosomes and mitochondria]. PMID- 4302479 TI - [Radiotherapy in childhood]. PMID- 4302480 TI - [Relationships between weight of tumor transplanted in embryonated eggs and weight of its host]. PMID- 4302482 TI - [Infections with an adenovirus related to type 31 and wtih other adenoviruses with a higher type number]. PMID- 4302481 TI - [Effect of Bordetella pertussis on the lymphatic tissue of mice. II. Proliferating cell systems in the spleen after the injection of Bordetella pertussis]. PMID- 4302483 TI - [Primary mucinous adenocarcinoma of the renal pelvis and ureter: a case report and review of literature]. PMID- 4302484 TI - Mixed haemadsorption with Herpes simplex virus. PMID- 4302485 TI - [On the amount of dust in the vicinity of cement plants in view of possible damage to health. II]. PMID- 4302486 TI - [Detection of complement-fixing serum antibodies against the respiratory syncytial virus in a smaple of the population of Rome]. PMID- 4302487 TI - Cystosarcoma phyllodes of the breast. A statisical study of forty cases. PMID- 4302488 TI - The effect of bone marrow transplantation on the survival of patients with advanced cancer. PMID- 4302489 TI - [The isolation and some properties of the plasma membranes from animal cells]. PMID- 4302490 TI - [The influence of regular muscle activity on the activity of the enzymes operating the conversion of glycogen and glucose-6-phosphate in muscles and liver]. PMID- 4302491 TI - [Study of phosphorus compounds of mitochrndria from Neurospora crassa]. PMID- 4302492 TI - [Seryl-pyrophosphate in the phosphotransferase reaction catalyzed by alkaline phosphatase from E. coli]. PMID- 4302493 TI - [Cytochromes of Micrococcus lysodeikticus]. PMID- 4302494 TI - [Electron spin resonance study of catalase and some catalase compounds]. PMID- 4302495 TI - [Electron spin resonance studies of cytochrome C and some cytochrome C compounds]. PMID- 4302496 TI - Potentiation by silica of the growth of Mycobacterium tuberculosis in macrophage cultures. PMID- 4302497 TI - The production and effect of interferon in organ cultures of calf trachea. PMID- 4302498 TI - Enzymatic analysis of sclera. PMID- 4302499 TI - Quantitative histochemistry of histamine, and histidine decarboxylase in the stomach of rat, pig, and dog in various functional states. PMID- 4302500 TI - Epidemiology of pancreatic cancer in Connecticut. PMID- 4302501 TI - Radicals formed by electron transfer to pyrimidine derivatives. PMID- 4302502 TI - Radical formation in cysteamine free base and cystamine.2HCl by reaction with atomic hydrogen and by gamma-irradiation. PMID- 4302503 TI - [Review on dental biochemistry]. PMID- 4302504 TI - [Endocrinological study on prostatic carcinoma: anti-androgenic therapy and extragonadal androgens (analysis of 17-ketosteroid fractions by gas-liquid chromatography]. PMID- 4302505 TI - [Study on androgen metabolism in urological fields. Study on urinary testosterone glucuronide]. PMID- 4302506 TI - [The activity of renin and angiotensinase in blood plasma of patients with acute myocardial infarct]. PMID- 4302507 TI - [Effect of unilateral injuries of the kidneys on the blood pressure level and urinary excretion of aldosterone in the rat]. PMID- 4302508 TI - [Biological and pharmacological studies on Tuberactin, a new antibiotic]. PMID- 4302509 TI - Effect of different proteins (casein, gluten, zein) and supplements of amino acids (lysine, tryptophan) on hepatic injuries induced by p dimethylaminoazobenzene. PMID- 4302510 TI - [Evaluation of left ventricular efficiency during infusion of beta-angiotensin II. Studies with the polygraphic method]. PMID- 4302511 TI - [Post-vaccinal study of a poliovirus I epidemic]. PMID- 4302512 TI - The syndrome of congenital adrenocortical unresponsiveness to ACTH. Report of six cases. PMID- 4302513 TI - Prevention of the normal postnatal increase in drug-metabolizing enzyme activity in rat liver by a pituitary tumor. PMID- 4302514 TI - Renal function in the iso- lated perfused kidney. PMID- 4302515 TI - Cander risk in intraductal papilloma and papillomatosis. PMID- 4302516 TI - [Virological studies on the explanation of intrauterine embryonal defects]. PMID- 4302517 TI - [Primary duodenal cancer]. PMID- 4302518 TI - [Influence of reagents on measurement values in LDH and transaminase determinations]. PMID- 4302519 TI - [Effect of ionizing radiation on Mg metabolism]. PMID- 4302520 TI - [Liver enzymes in acute carbon tetrachloride poisoning. A contribution to the mechanism of serum enzyme variations]. PMID- 4302521 TI - [Determination of prostate phosphatase with alpha-naphthyl phosphate in the presenec of bilirubin]. PMID- 4302522 TI - [An approved method for the routine determination of protein-bound iodine (PBI)]. PMID- 4302523 TI - [Ca++, histidine, and Zn++ as factors in the formation of giant cells by herpesivirus hominis]. PMID- 4302524 TI - [Substrates and competitive inhibitor of assimilatory and dissimilatory nitrate reductase of Aerobacter aerogenes]. PMID- 4302526 TI - [Special synapses in the midbrain of the carp (Cyprinus carpio)]. PMID- 4302527 TI - [Histological observations on the so-called salivary mixed tumor with special reference to the relation between the tumor growth and mucoid stubstance]. PMID- 4302525 TI - [Occurrence of hemagglutination inhibiting abtibodies for parainfluenza viruses in various animal species]. PMID- 4302528 TI - The control of corpus luteum function in the ferret. PMID- 4302529 TI - Renal stone. PMID- 4302530 TI - Meningiomas and fibroblastic neoplasia in calves induced with the bovine papilloma virus. PMID- 4302531 TI - The heterogeneity of DNA polymerases in rat liver and hepatomas. PMID- 4302532 TI - Nonvirus-associated antigens in virus-induced mouse mammary tumors. PMID- 4302533 TI - The antigenicity and immunogenicity of cell-free extracts of chemically induced murine sarcomas. PMID- 4302534 TI - S-adenosylmethionine synthetase activity in some normal rat tissues and transplantable hepatomas. PMID- 4302535 TI - Antigenic characteristics of lymphomas induced by radiation leukemia virus (RadLV) in mice and rats. PMID- 4302536 TI - Comparative studies of fluorinated pyrimidines with various cell lines. PMID- 4302537 TI - Metabolic properties of mouse transplantable adenocarcinoma. PMID- 4302538 TI - Angiotensin and the Stouffer prize. PMID- 4302539 TI - Diminished baroreflex sensitivity in high blood pressure. PMID- 4302540 TI - [Progress and problems in the diagnosis and therapy of urogenital tuberculosis]. PMID- 4302541 TI - Oral medicine seminar. No. 16--oral cancer. PMID- 4302542 TI - Teratological studies with sulphonamides and their implications. PMID- 4302543 TI - The effect of rubella and herpesvirus homonis on the pre- and post-implantation stages of pregnancy in laboratory animals. PMID- 4302544 TI - Enzyme ontogeny in normal and hemimelic limbs of mice. PMID- 4302545 TI - Hepatorenal glycogenosis (type I glycogenosis) and carcinoma of the liver. PMID- 4302546 TI - Norethandrolone in cystic fibrosis of the pancreas. PMID- 4302547 TI - Reserpine- and chlorpromazine-induced changes in hypothalamo-hypophyseal-adrenal system in rats in the presence and absence of hypothermia. PMID- 4302548 TI - Some features of barbiturate interaction and inhibition of NADH-cytochrome C oxidoreductase in respiring systems. PMID- 4302549 TI - The direct effect of norepinephrine of angiotensin on the pulmonary veins of intact dogs. PMID- 4302550 TI - Nursing rediscovered. PMID- 4302551 TI - Foreword and general management. PMID- 4302552 TI - Treatment of metabolic neuropathies. PMID- 4302553 TI - Treatment of toxic and drug induced neuropathies. PMID- 4302554 TI - Treatment of deficiency and alcoholic neuropathies. PMID- 4302556 TI - Avian virus-induced tumors. PMID- 4302555 TI - Treatment of neuropathies accompanying inflammatory, vascular and neoplastic conditions. PMID- 4302557 TI - [Granular cell myoblastoma. 4 cases encountered in a review of oral cavity biopsies at the I. A. P]. PMID- 4302558 TI - "Asterinsaure"--an acetylenic carotenoid. PMID- 4302559 TI - Tissue culture study of glioblastoma cells with addition of autologous lymphocytes. PMID- 4302560 TI - [Effect of sound on the reaction of collicular neurons]. PMID- 4302561 TI - [Clinical and biologic symptoms of secretory beta-Langerhansian cell adenoma]. PMID- 4302562 TI - [Angiography of hypoglycemic Langerhansian adenoma]. PMID- 4302563 TI - [Langerhansian hyperplasia and tumors with beta cells. Histology and ultrastructure]. PMID- 4302564 TI - [Surgical treatment of Langerhansian adenoma]. PMID- 4302565 TI - [Nonsecretory nesidioblastoma of ectopic localization (duodenal)]. PMID- 4302566 TI - Hepatic lobectomy for hepatoblastoma in infants and children. PMID- 4302567 TI - Cholinergic link hypothesis and sympathetic transmission at the nictitating membrane of the dog. PMID- 4302568 TI - [Elective suppression of paradoxal sleep in cats by alpha-methyl DOPA]. PMID- 4302569 TI - [Study of the course of sleep in the young rat during the 1st postnatal month]. PMID- 4302570 TI - [Abnormal presence of isozymes of lactic dehydrogenase, heart type, in experimental hepatomas]. PMID- 4302571 TI - Reduction and detection of aromatic nitro-compounds on thin layers of silica gel. PMID- 4302572 TI - Improved thin-layer chromatographic separation of amanita toxins on Silica Gel G chromatoplates. PMID- 4302573 TI - Variations in the cell cycle during azo dye hepatocarcinogenesis. PMID- 4302574 TI - Enhancement of urethan induction of hepatomas in mice by prior partial hepatectomy. PMID- 4302575 TI - Observations on a cell line producing mammary tumor virus. PMID- 4302576 TI - Methods for detection of antibody to the mammary tumor virus. PMID- 4302577 TI - Establishment of a cell line from an inbred mouse strain for viral transformation studies: simian virus 40 transformation and tumor production. PMID- 4302578 TI - Site of genetic regulation on hypophysial graft-induced mammary gland development. PMID- 4302579 TI - Quantitative distribution of virions in virus-induced murine leukemia. PMID- 4302580 TI - Preliminary note. Identity of a herpesvirus antigen from Burkitt lymphoma of man and the Lucke adenocarcinoma of frogs. PMID- 4302581 TI - Current trends in nursing education with implications for nursing service. PMID- 4302582 TI - In vivo effects of anti-angiotensin II on the renin-system. Share of the reninsystem in the normal blood pressure level, and the mechanism of the changed response to renin in nephrectomised rats. PMID- 4302583 TI - Virus-like particles in Rous rat sarcoma. PMID- 4302584 TI - Investigations on the enzymes and toxins of staphylococci. Relations of pH to growth and production of enzymes. PMID- 4302585 TI - [Seborrheal (senile) wart]. PMID- 4302586 TI - [Insulin-producing adenomas of the pancreas]. PMID- 4302587 TI - [Effect of novocaine and vitamin C on the fibrogenic action of quartz dust]. PMID- 4302588 TI - Zoster encephalitis: a case report. PMID- 4302589 TI - [Peritoneal perfusion with antienzymes in the therapy of acute experimental pancreatitis]. PMID- 4302590 TI - [Behavior of serum phosphates in prostatic neoplasms after hormonal stimulation. (Experimental study)]. PMID- 4302591 TI - The effect of hypnotics on rapid eye movement (REM). PMID- 4302592 TI - [Endoccinological changes as a result of obesity in juveniles]. PMID- 4302593 TI - Histochemistry of human cervical posterior root ganglion cells and a comparison with anterior horn cells. PMID- 4302594 TI - Histidine regulatory mutants in Salmonella typhimurium. V. Two new classes histidine regulatory mutants. PMID- 4302595 TI - Histidine regulatory mutants in Salmonella typhiumium. VI. Dominance studies. PMID- 4302596 TI - Primary mucoid adenocarcinoma of the prostate gland with bladder invasion. PMID- 4302597 TI - [Principles of histochemical localization of cytochrome oxidases and peroxidases]. PMID- 4302598 TI - The effect of the seed of Musa superba Roxb. on small-pox virus. PMID- 4302599 TI - [Endemic nephropathy in Yugoslavia]. PMID- 4302600 TI - [Clinical picture and therapy of urachal carcinoma]. PMID- 4302601 TI - [Preparation ofhyperimmune influenza, para-influenza, and adenovirus sera]. PMID- 4302602 TI - [Circulation of respiratory viruses among children during the years 1948-1956]. PMID- 4302603 TI - [Dynamics of changes in the non-specific phosphatases in the central nervous systems of white mice infected with the virus of acute human encephalomyelitis]. PMID- 4302604 TI - [Formation of hemaglutinins and infectious Sendai virus in the cells of Ehrlich's ascites carcinoma]. PMID- 4302605 TI - [A study of polyoma virus in various tissue culture systems. Chronic infection of transplantable APO-1 cells induced by polyoma virus]. PMID- 4302606 TI - [The effect of cystine on the chromatographic behavior and thermostability of variants of poliomyelitis virus]. PMID- 4302607 TI - [A method of producing hyperactive sera against various respiratory viruses]. PMID- 4302608 TI - [Micromethod for the HI test in the diagnosis of influenza and para-influenza infections]. PMID- 4302609 TI - [Principles and new results in the histochemical demonstration of dehydrogenases with tetrazolium salts]. PMID- 4302610 TI - Ultrastructural observations on the droplets of experimentally-induced goitres in Xenopus laevis with especial reference to the development of Uhlenhuth colloid cells. PMID- 4302611 TI - Methotrexate therapy in trophoblastic disease at the Provinical Taipei Hospital (1955-1966). A re-evaluation and proposals. PMID- 4302612 TI - Central actions of lidocaine--synaptic transmission. PMID- 4302613 TI - Action of lidocaine in the central nervous system. PMID- 4302614 TI - The electromechanical response to stimulation by the Block-Aid Monitor. PMID- 4302615 TI - Local anesthetic seizures. PMID- 4302616 TI - Influence of microorganisms on mammalian metabolism and nutrition, with specific reference to oxygen, consumption, carbon dioxide production, and colonic temperature. PMID- 4302617 TI - [Cylindromas of the skin]. PMID- 4302618 TI - [Data towards the histochemical characteristics of brain tumors in rats]. PMID- 4302619 TI - [On morphological grouping and clinical anatomical comparisons in malignant synoviomas]. PMID- 4302620 TI - [Histochemical study of the enzymes of the liver in humans with chronic hepatitis and cirrhosis]. PMID- 4302621 TI - Effect of gold salts and other drugs on the release and activity of lysosomal hydrolases. PMID- 4302622 TI - The assay of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate in biological materials by enzymatic radioisotopic displacement. PMID- 4302623 TI - The theoretical basis for the measurement. PMID- 4302624 TI - Investigations of inter- and intramolecular interations in flavin--adenine dinucleotide by proton magnetic resonance. PMID- 4302625 TI - Studies on oxidative phosphorylation. XVI. Sulfhydryl involvement in the energy transfer pathway. PMID- 4302626 TI - [Cytochrome-C-oxidase of liver mitochondria in the guinea pig in anaphylactic shock]. PMID- 4302627 TI - Bronchopneumonia with serious sequelae in children with evidence of adenovirus type 21 infection. AB - Twenty-five cases of severe pneumonitis occurring among children aged 3 to 18 months were observed in Auckland, New Zealand, in 1965. An apparent relationship was established between a uniform disease picture and recovery of adenovirus type 21. Two died, and of the survivors 60% had permanent lung damage, probably resulting from obliterative bronchiolitis. Twenty per cent. were left with proved bronchiectasis. The possible relationships of adenovirus pneumonia to malnutrition or a genetic factor on the one hand and to the development of bronchiectasis on the other are discussed. PMID- 4302628 TI - Radioactive selenium labeling of rat insulin in vivo. PMID- 4302629 TI - [Some data on the status of the organ of sight in persons engaged in the production of construction glass]. PMID- 4302630 TI - Motor nerve terminals as the site of initial functional changes after denervation. AB - For the cat soleus nerve-muscle system, motor nerve section 48 hr prior to in situ experiment causes certain characteristic transmission losses. Responses to repetitive stimulation are sharply altered: The capacity to transmit iterative stimulation is severely reduced; post-tetanic potentiation and the post-tetanic repetition of soleus nerve terminals responsible for it are also greatly impaired; a phenomenon of post-tetanic depression was frequently observed. However, function of the extramuscular axons appears normal and single impulse transmission is usually not seriously affected. The loss of reactivity to repetitive stimulation has been traced to soleus motor nerve terminals. In view of these data and the known absence of denervation hypersensitivity at this time, the earliest functional failure may be said to occur in the unmyelinated terminals. This subacutely denervated preparation therefore offers a simple means of evaluating motor nerve terminal responsiveness. PMID- 4302631 TI - Transcription during bacteriophage T4 development: requirements for late messenger synthesis. PMID- 4302632 TI - Morphogenesis of poliovirus. I. Association of the viral RNA with coat protein. PMID- 4302633 TI - [On the origin of silicosis]. PMID- 4302634 TI - Embryotoxic activity of hypoglycin-A in the rat. PMID- 4302635 TI - Morphological changes in the rat hypothalamus and adrenal cortex in the early postnatal period after ACTH and hydrocortisone administration, stress, and adrenalectomy. PMID- 4302636 TI - Vasopressin test in central nervous system-pituitary disorders. PMID- 4302637 TI - On the sulfur components of iron-sulfur proteins. I. The number of acid-labile sulfur groups sharing an unpaired electron with iron. PMID- 4302638 TI - Early release of growth inhibition in cells infected with Rous sarcoma virus. PMID- 4302639 TI - Regulation of transcription of the SV40 DNA in productively infected and in transformed cells. PMID- 4302640 TI - Inhibition by nucleotides of liver microsomal glucose-6-phosphatase. PMID- 4302641 TI - Flavoproteins of the electron transport system and the site of action of amytal, rotenone, and piericidin A. PMID- 4302642 TI - [Inhibition of the lipolytic effect of ACTH using specific antibodies]. PMID- 4302643 TI - [The adrenocorticotropic effect of a synthetic beta-1-24 corticotropin derivative]. PMID- 4302644 TI - [Lymphography and intra-osseous pelvic phlebography in the diagnosis of metastasing tumors of the urinary bladder]. PMID- 4302645 TI - [Studies on the enzymatic determination of galactose with galactose oxidase]. PMID- 4302646 TI - [Contrast media]. PMID- 4302647 TI - The effects of different preparative approaches on the ultramorphological appearance of the Kirkman-Robbins hepatoma in the hamster. PMID- 4302648 TI - [Angiography of benign tumors of the liver]. PMID- 4302649 TI - [Neurinomas of the acoustic nerve and other tumors of the ponto-cerebellar angle. Otovestibular aspects and their neurological correlations]. PMID- 4302650 TI - [Possibility of using histo- and cytochemical determination of phosphorylase in the diagnosis of breast tumors]. PMID- 4302651 TI - [Parallel detection of nucleoproteids in breast tumors in cytological and histological preparations]. PMID- 4302652 TI - [2 rare tumors of the trachea]. PMID- 4302653 TI - Malignant neoplasms of the central nervous system, Onatrio Cancer Foundation clinics, 1950-1964. PMID- 4302654 TI - Neurogenic control of the blood pressure in hypertension. PMID- 4302655 TI - [Effect of tropic hormones on the regeneration of adrenal glands in Sprague Dawley rats]. PMID- 4302656 TI - [Hypophyseal reserve in patients after halothane and ether anesthesia]. PMID- 4302657 TI - [Changes in some enzymes of the liver during the evolution of intestinal occlusion. Experimental study. I]. PMID- 4302658 TI - [Clinical and immunological research on 30 patients affected by recurring herpes after specific vaccination]. PMID- 4302659 TI - Modern cultism. PMID- 4302660 TI - Intrabulbar inoculation of Japanese encephalitis virus to mice. PMID- 4302661 TI - [Determination of plasma renin]. PMID- 4302662 TI - [Cl. perfringens and alimentary toxinfections]. PMID- 4302663 TI - Hypotheses on physiological roles of prostaglandins. PMID- 4302664 TI - Cytochrome oxidase. PMID- 4302665 TI - [Observations on the cytopathic effect of Herpes simplex virus]. PMID- 4302666 TI - [Contribution to the study of cytomegalic disease. Problems in differential diagnosis from toxoplasmosis]. PMID- 4302667 TI - [Viruses causing paralysis in Mexico]. PMID- 4302668 TI - [The inferior vena cava syndrome]. PMID- 4302669 TI - [The functional morphology of the normal and pathological myocardium]. PMID- 4302670 TI - [The regulation of myocardial metabolism]. PMID- 4302671 TI - [Electrotherapy of the heart and its after care]. PMID- 4302672 TI - [Calcifying aortic stenosis as an osteogenic cardiopathy]. PMID- 4302674 TI - The two stages of slow wave sleep in the cat and their relation to REM sleep. PMID- 4302675 TI - The effect of high doses of 5-hydroxytryptophan on a patient with trisomy 21. Clinical, chemical and EEG correlations. PMID- 4302676 TI - Monosynaptic reflex during natural sleep in the kitten. PMID- 4302677 TI - Organismic supercategories. I. Proposals for a general unitary theory of systems. PMID- 4302678 TI - Phosphonolipids. XVII. Synthesis of ethylene glycolphosphonic acid analogues of lecithins. PMID- 4302679 TI - [Intraocular complications in mixed tumor of the orbit]. PMID- 4302680 TI - Enhancement of radiation effects by phosphate buffer at 77 degrees K. PMID- 4302681 TI - Mucus producing carcinoma of the kidney. Report of a case. PMID- 4302682 TI - Adrenocorticotropins. XXXIX. The solid phase synthesis of methion-glutamyl histidyl-phenylalanyl-arginyl-tryptophyl-glycine. PMID- 4302683 TI - The fine structure of proliferating cells in preneoplastic rat livers during azo dye carcinogenesis. AB - The continuous feeding of the carcinogenic aminoazo dye DAB to rats produces hyperbasophilic foci in the preneoplastic livers. After injections of thymidine (3)H into the rats, such foci were isolated from the livers and studied by radioautography with the phase-contrast and electron microscopes. In these foci, the only cells found to be proliferating, as determined by the uptake of thymidine-(3)H into their nuclei, were a poorly differentiated type; well differentiated hepatocytes in the same regions were not labeled with the isotope. The labeled cells had an irregular cell outline and a high nucleocytoplasmic ratio; the cytoplasm had almost completely lost the specialized elements characteristic of hepatocytes; the irregular nuclei with prominent nucleoli, the altered mitochondria, and the increased free ribosomes noted in these cells are features which are characteristic of neoplastic cells induced by DAB. Thus, it seems likely that the hyperbasophilic foci represent the sites of extensive dedifferentiation of hepatocytes followed by rapid cellular proliferation, leading to neoplastic growth. PMID- 4302684 TI - Synergistic effect in viral-bacterial infection. I. Combined infection of the respiratory tract in mice with parainfluenza virus and Hemophilus influenza. PMID- 4302685 TI - Behavior of equine infectious anemia virus in cell culture and development of a diagnostic test for the disease. PMID- 4302686 TI - The ultrastructure of a tumor of the glomus jugulare. PMID- 4302687 TI - Glomus tumor of the nasal cavity. PMID- 4302688 TI - Hyperbaric oxygen radiotherapy and the need for preliminary myringotomy. PMID- 4302689 TI - Tumors of major salivary glands. Review of 100 consecutive cases treated at the Royal Victoria Hospital, Montreal, Canada. PMID- 4302690 TI - [Contribution to the study of influenzal, adenoviral and ornithosic antibodies in umbilical cord blood]. PMID- 4302691 TI - [Collection of blood on filter paper disks for the purpose of serological studies]. PMID- 4302692 TI - Oncogenicity of mixtures of adeno-associated virus and adenovirus type 12. PMID- 4302693 TI - Mossbauer effect in the ferredoxin of Euglena. PMID- 4302694 TI - Biological significance of a peculiar pattern of hormone release from iodine deficient rat goitres. PMID- 4302695 TI - Central pressor effect of angiotensin mediated by the parasympathetic nervous system. PMID- 4302696 TI - Cellular and humoral immunity to different types of human neoplasms. PMID- 4302697 TI - Antibody synthesis in vitro by lymph nodes from hamsters bearing adenovirus 12 tumours. PMID- 4302698 TI - Mediastinal cysts and tumors. PMID- 4302699 TI - [Effect of aminoglutethimide on excretion of ACTH and adrenal hormones]. PMID- 4302700 TI - Pediatric neurology. PMID- 4302701 TI - The in vivo effects of quartz and carbon dusts on the activity of cytochrome C oxidase and the DNA and RNA content of lung tissue. PMID- 4302702 TI - [Notes on estimation of the renin activity of plasma by Boucher's method]. PMID- 4302703 TI - Studies of the development of congenital anomalies in embryos of riboflavin deficient, galactoflavin fed rats. II. Role of the terminal elec-tron transport systems. PMID- 4302704 TI - [Current data on the pharmacology of diuretics]. PMID- 4302705 TI - Dialysis and transplantation: some interactions and comparisons. PMID- 4302706 TI - [Experimental findings on the question of intertype relations in the para influenza virus family]. PMID- 4302707 TI - [Permeability of the blood-brain barrier to various strains of poliovirus]. PMID- 4302708 TI - [Development of tumors in Syrian hamsters during their infection by Shope rabbit papilloma virus]. PMID- 4302709 TI - [On an outbreak of epidemic keratoconjunctivitis in Moscow in 1963-4]. PMID- 4302710 TI - [On the problem of the spread of rhinovirus infections among adults and young children]. PMID- 4302711 TI - [The influence of structural differences of the gyral and sulcal areas of the acoustic projection cortex on primary induced acoustic responses]. PMID- 4302712 TI - [The influence of angiotensin on the glucose blood level in rabbits]. PMID- 4302713 TI - Biosynthesis of rubber. PMID- 4302714 TI - The biochemistry of the functional psychoses. PMID- 4302715 TI - Ketogenesis and its regulation. PMID- 4302716 TI - Experiences with AGA thermovision in breast disease and survey programmes. PMID- 4302717 TI - A new method for the quantitative determination of monosaccharides, amino sugars and N-acetylneuraminic acid and of 6-deoxyhexose (fucose) in the presence of other sugars. AB - 1. Monosaccharides, amino sugars and N-acetylneuraminic acid were determined by using an original colorimetric assay procedure, based on the detection of formaldehyde released after periodate oxidation. A range of these compounds was investigated by this method and they were all found to obey Beer's law within the concentration range 0-0.6mumole/ml. 2. A simple method for the determination of 6 deoxyhexose concentration in the presence of other monosaccharides is also described. 3. The optimum pH for the release of formaldehyde from sugars by periodate oxidation was 7.0-7.5. 4. The methods described have considerable advantages over existing assay systems and their particlar value in automatic colorimetry, where the use of concentrated acids is undesirable, is discussed. PMID- 4302718 TI - The effect of infection with fowl-plague virus on protein synthesis in chick embryo cells. PMID- 4302719 TI - Ribonucleic acid synthesis in fowl-plague virus-infected chick-embryo cells. PMID- 4302720 TI - The incorporation of [14C3]glycerol into lipids by dispersed bovine mammary cells. PMID- 4302721 TI - Enzymatic hydrolysis of phosphosphingolipids by Clostridium perfringens phospholipase C. PMID- 4302722 TI - Fluorescence and protein structure. XIV. Tyrosine fluorescence in helical muscle proteins. PMID- 4302723 TI - Probe of subunit structure in fungal p-diphenol oxidase by treatment with guanidine hydrochloride and at high pH. PMID- 4302724 TI - Isolation of collagens of high hydroxyproline, hydroxylsine and carbohydrate content from muscle layer of Ascaris lumbricoides and pig kidney. PMID- 4302725 TI - The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea-pig ileum longitudinal muscle strip. AB - 1. Noradrenaline and adrenaline reduce the output of acetylcholine by the guinea pig ileum longitudinal strip by up to 80%, both in resting conditions and after stimulation. The effect is graded with dose, and is detectable with noradrenaline 2 x 10(-7) g/ml. Adrenaline is approximately 4 times as active as noradrenaline, and its action after being washed out is more persistent.2. If resting output is high, both amines have a proportionately greater effect and their action, as dosage is increased, is to reduce resting output to a basal level, relatively constant from strip to strip, of about 10 ng/g/min.3. With stimulation, the effect of the amine is greater at low frequencies, when the output per volley is high, than at high frequencies. The effect is reduced by increasing the number of shocks delivered. There thus appears to be a basal output per volley, of the order of 1-2 ng/g/volley, which can be reached either by relatively rapid stimulation, by prolonged stimulation, or by treatment with these amines.4. If noradrenaline is applied during continued stimulation at 40/min, the depression of acetylcholine output during its presence is followed by an augmented output when the drug is withdrawn. The magnitude of this "overshoot" increases with the duration of noradrenaline exposure.5. Phenylephrine 4 mug/ml. and amphetamine 20 mug/ml. reduced the acetylcholine output, but isoprenaline 1 mug/ml., dopamine 1 mug/ml. and methoxamine 10 mug/ml. were ineffective.6. Phenoxybenzamine reduced the resting output and increased the stimulation output. Of the two other blocking agents examined, phentolamine had no effect on either resting or stimulation output and ergotamine transiently reduced stimulation output. The effect of phenoxybenzamine was not due to a reaction with either adrenoceptive or muscarinic receptors.7. Phenoxybenzamine, phentolamine and ergotamine abolished the effect of adrenaline and noradrenaline on both resting output and on output in response to stimulation.8. In strips obtained from animals treated with reserpine and guanethidine, a rise in resting acetylcholine output and in stimulation output at low frequencies was found. In these conditions, noradrenaline was still effective.9. Reducing the hydroxytryptamine content of the strips by treatment with p-chloro-(+/-)-phenylalanine did not significantly affect acetylcholine output.10. It is concluded that acetylcholine output by the nervous networks of the longitudinal strip is under the normal control of the sympathetic by a species of presynaptic inhibition mediated by alpha receptors. This implies that for a tissue under dual autonomic control, withdrawal of sympathetic control will lead to a parasympathetic response which is not only unopposed but also itself enhanced. PMID- 4302726 TI - Inhibition by lidoflazine of the contractile response of the rat isolated colon to angiotensin. AB - 1. In the rat isolated ascending colon, lidoflazine in a concentration of 5 x 10( 7)M slightly enhanced the response to angiotensin, but in a concentration of 10( 6)M it was a strong and unsurmountable antagonist.2. Exposure to lidoflazine (10( 6)M) also inhibited the contractile responses to acetylcholine, 5 hydroxytryptamine and barium ions. The antagonism of acetylcholine and 5 hydroxytryptamine was unsurmountable and quantitatively similar to that of angiotensin. The antagonism of barium ions was much weaker and probably competitive.3. The inhibitory effect of papaverine (10(-5)M) showed a pattern similar to that found for lidoflazine.4. It is concluded that the antagonism of angiotensin by lidoflazine in the rat colon is non-specific. PMID- 4302727 TI - Post-tetanic and drug-induced repetitive firing in the soleus muscle of the cat. AB - 1. The effects of a high frequency indirect tetanus on the responses to subsequent infrequently applied nerve shocks have been compared in the tibialis anterior and soleus muscles of cats and rabbits.2. Post-tetanic augmentation of twitches in the cat soleus muscle was shown to be partly due to repetitive firing and partly due to increased synchronization of the muscle fibre response. Post tetanic repetitive firing was not evident in the responses of the other three muscles studied.3. Post-tetanic repetitive responses in the cat soleus muscle and nerve did not originate in the nerve trunk and were not produced by direct muscle stimulation; they were abolished by doses of tubocurarine smaller than those necessary to reduce the twitch tension below the pre-tetanic level. These findings support the conclusion of others that the repetitive firing originates at the neuromuscular junction.4. The repetitive firing could not be explained by an increase in the sensitivity of the motor endplates to acetylcholine, suggesting that an increase in and/or a prolongation of the output of transmitter from the motor nerve contributes to it.5. The cat soleus muscle was shown to be more sensitive to neostigmine than were the other three muscles studied, and acetylcholinesterase determinations showed that this muscle possesses less enzyme activity.6. It is concluded that an increase in transmitter output, coupled with a weaker cholinesterase activity, probably accounts for the post-tetanic repetitive activity in the cat soleus muscle.7. Post-tetanic repetitive firing was absent in cat soleus muscles which had been cross-innervated with the nerve formerly innervating a fast-contracting muscle. PMID- 4302728 TI - Preparation and evaluation of standardized amoeba antigen from axenic cultures of Entamoeba histolytica. AB - The successful mass cultivation of Entamoeba histolytica strains in pure culture has made it possible to produce pure amoeba antigens, which should improve the prospects for immunodiagnostic research and simplify the interpretation of the results obtained in tests for amoeba antibodies.The authors have mass-produced immunodiagnostic antigens for amoebiasis serology from 2 axenic strains of E. histolytica and standardized them as dry powders, which upon reconstitution contained approximately 1.8 mg N/ml, or roughly the equivalent of 10 x 10(6) amoebae per ml.The antigens were evaluated with 121 sera from subjects in Costa Rica, South Africa, Taiwan, Thailand and the USA, 49 of the sera being from cases of amoebic liver abscess, 41 from symptomatic intestinal amoebiasis, 19 from asymptomatic intestinal amoebiasis, and 12 from subjects presumed not to have amoebiasis.Positive results with the indirect haemagglutination test were obtained with 100% of amoebic liver abscess sera, 90.2% of those from symptomatic intestinal amoebiasis, 57.9% of those from asymptomatic intestinal amoebiasis, and 16.7% of the normal sera. Positive complement-fixation tests for the respective groups were obtained in 83.8%, 63.3%, 10.5% and 0%, and positive agar gel diffusion in 79.6%, 53.7%, 0% and 0%.These results compare favourably with earlier reports of similar studies in which non-axenic cultures were used and agree well with those of investigators in different parts of the world to whom samples of the axenic antigens were sent.The authors conclude that the axenic antigens from either strain used, or from the 2 strains pooled, are of broad usefulness in the detection of amoebic antibodies, but point out that the limitations of the tests now used in amoeba serology are not yet clearly understood and that the pattern of antibody persistence after infection requires further study. PMID- 4302729 TI - [Incidence of viral infections among the population of Easter Island. Serological study]. PMID- 4302730 TI - [Action of thyroid hormones on the oxidoreduction state of respiratory coenzymes]. PMID- 4302731 TI - [Research on the mechanism of oxidations in Pseudomonas fluorescens. IV. Role of dihydroorotate dehydrogenase]. PMID- 4302732 TI - Radioimmunoassay of ACTH and growth hormone. PMID- 4302733 TI - [Glyco-active corticosteroid hormones and the nervous system: study of their transit across the blood-cerebrospinal fluid barrier. Deductions for therapeutic purposes]. PMID- 4302734 TI - [Tyrosyl-tRNA synthetase of Escherichia coli. 1. Study of the complexes tyrosyl AMP:enzyme and tyrosinyl-AMP:enzyme]. PMID- 4302735 TI - Interrelationships between parasites and their hosts. IV. Cytochrome c oxidase thermal-acclimation patterns in a larval trematode and its host. PMID- 4302736 TI - Enzyme histochemistry of the adult liver fluke, Fasciola hepatica. PMID- 4302737 TI - [Considerations on a case of adenoma of the islands of Langerhans in an aged patient]. PMID- 4302738 TI - Separation of polyphosphates by anion exchange thin layer chromatography. PMID- 4302739 TI - The use of silver nitrate impregnated silica gel layers in the separation of monoterpene hydrocarbons. PMID- 4302740 TI - Effects of exogenous adrenocorticotropic hormone on palatogenesis in A-Jax mice. PMID- 4302741 TI - Immunochemical studies of foot-and-mouth disease. V. Antigenic variants of virus demonstrated by immunodiffusion analyses with 19S but not 7S antibodies. AB - Three antigenic variants of foot-and-mouth disease virus, type A, strain 119, were demonstrated in Ouchterlony analyses utilizing serum collected from guinea pigs 7 days postinfection (DPI). Such antisera contain antibodies of the 19S class. Guinea pig antisera that contained antibodies of the 7S class were unable to distinguish between the antigenic variants. Similarly, 19S antibody was able to demonstrate antigenic differences in trypsin- and chymotrypsin-treated viruses that were not detected by 7S antibody-containing antisera. One of the antigenic variants of virus is apparently the wild type and is tentatively considered to have two antigenic determinant groupings termed the a- and b-sites (140S-ab). The 140S-ab variant was the sole or predominant antigenic type produced in guinea pigs and in large plaque-forming- and tissue culture-low passage sources of the virus. Another antigenic variant appears to possess only the b-site (140S-b) and was the major constituent in tissue culture-high passage virus preparations. The third variant, a small plaque former, was also devoid of the a-site and contains an antigenic determinant that is related to, but not identical with, the b-site. This variant appears to be a minor constituent of tissue culture-high passage virus. 7-DPI serum could be absorbed with a suitable concentration of tissue culture-high passage virus to remove antibody reactive with the b-determinant site. This absorbed serum still precipitated 140S-ab virus by virtue of still containing antibody reactive with the a-determinant site; however, the neutralizing activity was eliminated. This suggests that the b-site is critical with respect to neutralization while the a-site is noncritical. PMID- 4302742 TI - [Clinical experience with the use of cold packs on the chest-back region for the treatment of high fever and encephalitis symptoms]. PMID- 4302743 TI - [Antiviral activity of benzimidazole derivatives. I. Synthesis and antiviral activity of hydroxyalkylbenzimidazole derivatives]. PMID- 4302744 TI - Effect of pH on the protective action of interferon in L cells. AB - The pH of the solution in which interferon was applied to L cells determined the level of resistance developed against challenge with vesicular stomatitis virus (VSV). No inhibition of challenge virus was observed when interferon was applied to cells at pH 6.0. At pH 6.5, partial inhibition of VSV replication was observed and inhibition was maximum at pH 7.0. Evidence was obtained that interferon interacted with L cells at pH 6.0, but that resistance did not develop until the cells were placed in a medium at pH 7.0. These effects were explained by data showing that exposure of cells to a medium at pH 6.0 reversibly inhibited both ribonucleic acid and protein synthesis. PMID- 4302745 TI - Kinetics of viral deoxyribonucleic acid, protein, and infectious particle production and alterations in host macromolecular syntheses in equine abortion (herpes) virus-infected cells. AB - Infection of exponential-phase suspension cultures of mouse fibroblast cells (L M) with equine abortion virus (EAV) resulted in inhibition of cell growth and marked alterations in host metabolic processes. The synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid was inhibited within 4 hr after infection and was suppressed by more than 90% by the time of maximal virus replication (14 to 18 hr). The overall rate of protein synthesis, however, was similar in uninfected and virus-producing cells as determined by measurements of net protein and isotope incorporation. The time course of viral DNA and protein synthesis and assembly into mature virus was determined with the inhibitors 5 fluorodeoxyuridine (FUdR) and cycloheximide, respectively. Thus, viral DNA synthesis was essentially completed at 14 hr, and viral protein and infectious virus synthesis was completed at 18 hr. Although the number of plaque-forming units (PFU) produced by FUdR-treated cells (10(3) to 10(4) PFU/ml) was at least 3 logs less than that produced by untreated cells, the yield of physical particles (as determined by electron microscopy) was approximately the same at 30 hr after infection. Besides being relatively non-infective, the particles produced in FUdR treated cells appeared morphologically incomplete as they contained little or no nucleoid material. PMID- 4302746 TI - Effect of anticellular serum on the attachment of enteroviruses to HeLa cells. AB - Anticellular serum (ACS), in the absence of an active complement system, was shown to inhibit the attachment of poliovirus types 1 and 2, echovirus type 6, and coxsackievirus types A13, B1, and B3 to viral receptors of live HeLa cells. This is the first report to provide evidence that ACS has an inhibitory effect on the interaction between host cells and coxsackieviruses of group B. The titer of inhibitory activity of ACS varied inversely with the cell concentration used, the reaction being virtually completed after an incubation period of 30 min at 37 C. The inhibitory activity of ACS persisted for more than 4 hr at 37 C, and was shown to be reversible at pH 2.0, revealing that although the receptors for attaching virus were inactivated by ACS the inactivation was not permanent. These findings are consistent with the concept that antibodies in the ACS combine with and blockade viral receptors located at the cell surface. An antiserum with a specificity for inhibiting attachment of coxsackievirus B1 was obtained by dual absorption of ACS with cells saturated with coxsackievirus type B3 and chymotrypsin-treated cells. These findings offer an approach whereby the antigenic relationship of viral receptors to other constituents of the cell surface can be studied. PMID- 4302747 TI - Cellular origin of a mouse leukemia viral ribonucleic acid. AB - Mouse erythroblastosis virus, a member of the mouse leukemia virus group, was obtained from chronically infected C(3)H mouse embryo cells and purified on sucrose gradients. The ribonucleic acid (RNA) extracted from ribonuclease-treated virus consisted of a rapidly sedimenting (72S) species and a more slowly sedimenting component (4 to 30S). The 72S RNA did not contain base sequences homologous to deoxyribonucleic acid (DNA) from infected cells as determined by hybridization studies. In contrast, the slowly sedimenting RNA enclosed within the virus had base sequences homologous to DNA from infected and uninfected C(3)H mouse embryo cells. PMID- 4302748 TI - Isolation of defective lysogens from Simian virus 40-transformed mouse kidney cultures. AB - Rescue of simian virus 40 (SV40) from hamster and murine cell lines transformed by nonirradiated or by ultraviolet (UV)-irradiated SV40 (10(-3) to 10(-5) survival) was studied. A combination of tests was employed to detect induction of SV40 synthesis: (i) co-cultivation with susceptible monkey kidney (CV-1) cells; (ii) treating mixtures of transformed and CV-1 cells with UV-irradiated Sendai virus (UV-Sendai) prior to co-cultivation; and (iii) plating untreated or UV Sendai-treated mixtures of transformed and CV-1 cells with freshly trypsinized CV 1 cells. The first and second tests provided a measure of the total infectious SV40 yield per culture, and the third test provided a measure of the frequency of induction (fraction of transformed cells giving rise to infectious centers). With the combination of tests, SV40 was rescued in all trials from TSV-5 hamster cells, mKS-BU100 mouse cells, and from several lines of mouse kidney cells transformed by UV-irradiated SV40 (mKS-U lines). The frequency of induction was about 7 x 10(-2) for TSV-5 cells, about 3 x 10(-3) for mKS-BU100 cells, greater than 10(-4) for the mKS-U lines which were "good" yielders, and about 10(-5) to 10(-4) for the mKS-U lines which were "average" yielders. SV40 of a plaque type different from parental virus was rescued from four of the mKS-U cell lines. Virus was also easily rescued from: (i) tumor cells produced from the mKS-A line of transformed mouse kidney cells; (ii) mouse kidney cells transformed by SV40 which had been rescued from mKS-BU100 cells; and (iii) tumor cells (HATS) which had been produced by inoculating newborn hamsters with SV40 rescued from mKS BU100 cells. The frequency of induction of HATS cells was of the same order of magnitude as the frequency of induction of TSV-5 cells. In a study of the kinetics of virus induction, it was shown that SV40 could be detected 28, 40, and 48.5 hr after UV-Sendai treatment of mixtures of CV-1 and TSV-5, HATS, or mKS BU100 cells, respectively. Although all of the mKS-U lines contained the SV40 specific tumor antigen, some were poor virus yielders (SV40 was recovered in less than 50% of the trials) and five lines were rare virus yielders (SV40 recovered only once in four or more trials). Forty-eight mKS-U lines were nonyielders; SV40 was never recovered by any test used thus far. UV-Sendai-treated mixtures of pairs of nonyielder mKS-U lines with CV-1 cells also did not yield infectious virus. Various factors affecting rescue have been discussed. The mKS-U lines which were poor virus yielders, rare yielders, or which never yielded virus have been classified tentatively as "defective lysogens" which contain mutational lesions at loci essential for detachment of SV40 from integration sites or for SV40 replication, or for both. PMID- 4302749 TI - Characterization of intracellular ribonucleic acid specific for the murine sarcoma-leukemia virus complex. AB - Virus particles were continuously produced by a cell line (78A1) of rat embryo fibroblasts that had been transformed by the murine sarcoma-leukemia virus complex. Since most of the mature virions were found in the extracellular fluid and were not cell-associated, a measurable quantity of viral ribonucleic acid (RNA) could not be extracted from these cells. Cycloheximide, a protein inhibitor, was successfully used to accumulate viral RNA within the cells. This ribonuclease-sensitive RNA, with a sedimentation coefficient of 71S, had the same base composition as the high molecular weight RNA (S(20,w) = 71) isolated from purified virions released by the transformed cells. PMID- 4302750 TI - Interferon production in mice by vesicular stomatitis virus. PMID- 4302751 TI - Viral agents in hepatitis. A review. PMID- 4302752 TI - [Experimental diaplacental carcinogenesis]. PMID- 4302753 TI - Conformational similarities of vitamin D and cholesterol as enzyme substrates. PMID- 4302754 TI - Mode of action of morphine-like drugs on autonomic neuro-effectors. PMID- 4302755 TI - Synthesis and activity of RNA polymerase of a temperature sensitive poliovirus mutant at an elevated temperature. PMID- 4302756 TI - Transformation of human blood lymphocytes under the influence of smallpox antigen. PMID- 4302757 TI - [On the cell cycle of ascites tumor]. PMID- 4302758 TI - Growth of ascites tumor and cell cycle. PMID- 4302759 TI - [Radical pancreatectomy for malignant secreting insuloma]. PMID- 4302760 TI - [Changes in lungs due to lymphography of extremities using oily media]. PMID- 4302761 TI - Trisomy 13-15. PMID- 4302762 TI - The superior and inferior mesenteric veins as collateral channels in inferior vena cava obstruction. PMID- 4302763 TI - [Action of vasodilators (p-oxyphenyl-butylaminoethanol) on the phosphatase activity of the kidney]. PMID- 4302764 TI - [Inhibition of the hemolytic activity of a submicronic amorphous silica by chicken egg yolk lipovitellin, phospholipids and steroids]. PMID- 4302765 TI - [Anatomo-histological aspects of the sheep ovary after inoculation of vaccinia virus]. PMID- 4302766 TI - [Physiological and pharmacological significance of prostaglandins]. PMID- 4302767 TI - [Statistical survey (1955-1965) of hepatic diseases autopsied at the Department of Pathology, Tokyo University]. PMID- 4302768 TI - [Niemann-Pick disease in adults in hepato-spleno-pulmonary form]. PMID- 4302769 TI - [Study in internal medicine of a drug combination with vascular effects. Apropos of 82 cases using eutergine]. PMID- 4302770 TI - [A study of the reproduction of type 2 para-influenza virus by the fluorescent antibody technic]. PMID- 4302771 TI - Changes of plasma renin in the adrenalectomized dog under different conditions. PMID- 4302772 TI - Relaxation spectrometry of biological systems. PMID- 4302773 TI - Comparative NADH-diaphorase content of isoniazid-resistant and isoniazid susceptible Mycobacterium tuberculosis. PMID- 4302774 TI - Hyponatraemia and renovascular hypertension. Case report with plasma renin and vascular sensitivity studies. PMID- 4302775 TI - Identification of the incubation product of Boucher's renin activity assay, by means of radioimmunoassays for angiotensin I and angiotensin II, and a converting enzyme preparation from lung tissue. PMID- 4302776 TI - Synthesis of N-acetylated deoxyribonucleoside 5'-triphosphates and their utilization in enzymatic formation of single-stranded polydeoxyribonucleotides. PMID- 4302777 TI - The properties of molecular fragments obtained on treating calfskin collagen with collagenase from Clostridium histolyticum. PMID- 4302778 TI - Molecular fragments of rat skin collagen obtained on collagenase digestion. PMID- 4302779 TI - The interconversion of liver glycogen synthetase a and b in vitro. PMID- 4302780 TI - The role of glucose, glucagon and glucocorticoids in the regulation of liver glycogen synthesis. PMID- 4302781 TI - Effects of ethanol infusion on the redox state and metabolite levels in rat liver in vivo. PMID- 4302782 TI - The biochemical morphology and morphogenesis of hepatomas. PMID- 4302783 TI - Activity of metronidazole against experimental tetanus and gas gangrene. PMID- 4302784 TI - Cyanide metabolism in higher plants. 3. The biosynthesis of beta-cyanolanine. PMID- 4302785 TI - Regulation of beta-galactosidase synthesis in Escherichia coli by cyclic adenosine 3',5'-monophosphate. PMID- 4302786 TI - Studies on the mechanism of fatty acid synthesis. XXI. The role of fructose 1,6 diphosphate in the stimulation of the fatty acid synthetase from pigeon liver. PMID- 4302787 TI - Synthesis of triacetic acid lactone by the pigeon liver fatty acid synthetase complex. PMID- 4302788 TI - The pyruvate-phosphate dikinase reaction. The fate of phosphate and the equilibrium. PMID- 4302789 TI - The nature of disaccharidases in human leukocytes. PMID- 4302790 TI - [Case of rectal cancer in a youth]. PMID- 4302791 TI - [Surgery of malignant tumors in infants and children]. PMID- 4302792 TI - [Radiation therapy of malignant tumors in children]. PMID- 4302793 TI - [Malignant tumors of the head and neck in children]. PMID- 4302794 TI - [Malignant tumors of the urinary tract and genital organs in children]. PMID- 4302795 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 5-1969. PMID- 4302796 TI - [The value of biologic half-life and cortisol secretion rate in the field of cortico-adrenal exploration]. PMID- 4302797 TI - [An observation of Conn's syndrome. Clinical and biological study]. PMID- 4302798 TI - [Effect of ACTH on the urinary excretion of adrenaline]. PMID- 4302799 TI - [Results of histological and histochemical examinations of rats treated with alpha-chymotrypsin]. PMID- 4302800 TI - Studies on the RNA from avian myeloblastosis virus. PMID- 4302801 TI - Chemical composition of the parainfluenza virus SV5. PMID- 4302802 TI - Evidence for the possible existence of two envelope antigenic determinants and corresponding cell receptors for avian tumor viruses. PMID- 4302803 TI - Dimethyl sulfoxide enhancement of transformation by polyoma virus. PMID- 4302804 TI - [An epidemiological and clinico-laboratory study of group diseases of an adenoviral nature]. PMID- 4302805 TI - [Comparative study of the reproduction of viruses of the subgroup variola vaccinia in L cells]. PMID- 4302806 TI - [Use of quantitative calculations of cytomorphologic changes in the characterization of the infectious process induced by adenoviruses in tissue culture. A study of the dynamics of adenovirus type 4 infection in a culture of amniotic cells]. PMID- 4302807 TI - [Various findings obtained in studying a transplantable strain of Shope rabbit carcinoma]. PMID- 4302808 TI - [Effect of prolonged passage of cells of hamster tumors induced by simian virus 40 on the isolation of the oncogenic virus and superinfection]. PMID- 4302809 TI - [Concentration of para-influenza viruses types 1, 2, and 3 on the erythrocytes of various species of animals and man]. PMID- 4302810 TI - [Experience in the rehabilitation of myocardial infarct]. PMID- 4302811 TI - Age-dependent changes in the level of lysosomal enzymes in the lymphatic organs of the guinea pig. PMID- 4302812 TI - Surgical problems in hemipelvectomy. PMID- 4302813 TI - Haemolytic-uraemic syndrome: survival after prolonged oliguria. PMID- 4302814 TI - [Studies of swine. 23. The effect of long term mineralo- and glucocorticoid application on the behavior of various electrolytes, glucose and leukocytes in the blood as well as 17-ketosteroids in the urine of clinically healthy and bilaterally adrenalectomized swine]. PMID- 4302815 TI - [Studies of swine. XXIV. The behavior of various electrolytes, glucose and leukocytes in the blood as well as 17-ketosteroids in the urine of clinically healthy as well as unilaterally and bilaterally adrenalectomized animals after different loading in the form of temperature changes as well as work output]. PMID- 4302816 TI - [Studies of swine. XXV. The effect of thyroidectomy on the bilaterally adrenalectomized animal]. PMID- 4302817 TI - [On the production of gas gangrene serum in general and of polyvalent gas gangrene aphylacto-serum of the horse especially using the simultaneous immunization method with the 4 known gas gangrene types in uno]. PMID- 4302818 TI - [Polyneuropathies]. PMID- 4302819 TI - Effect of non-pressor doses of synthetic B-angiotensin II. in adrenocortical insufficiency. PMID- 4302820 TI - [ESR studies on the radical structure in x-irradiated L-leucine hydrochloride]. PMID- 4302821 TI - Alteration of the microwave saturation behaviour after heat treatment in electron spin resonance studies of free radicals produced in DL-valine by x-irradiation. PMID- 4302822 TI - [Study of doubling time variations in pulmonary metastases of rectocolonic cancers treated by fluoro-5-uracil]. PMID- 4302823 TI - [Study of the inhibiting action of charcoal opposing the fibrosing action of quartz]. PMID- 4302824 TI - [Rhythmic activity and unit activity activated by flaxedil in the lumbar spinal cord of the cat]. PMID- 4302825 TI - [Intermediary metabolites of glycolysis and adenine nucleotides in rat liver in vivo. I. Effects of an ischemic cycle]. PMID- 4302826 TI - [Analysis of the activity of spinal cord neurons involved in the elaboration of a flexion reflex of cutaneous origin in cats]. PMID- 4302827 TI - [Intemediary metabolites of glycolysis and adenine nucleotides of rat liver in vivo. II. Effects of 2,4-nitrophenol]. PMID- 4302828 TI - [Influence of the administration of ACTH on the sialic acid content of normal human nasal secretion]. PMID- 4302829 TI - [Experimental studies on the effect of one ACTH dose. A contribution to the knowledge of homeostatic regulation]. PMID- 4302830 TI - Fetal infections. PMID- 4302831 TI - [The "cervico-facial gustatory hyperemia-hyperhidrosis" syndrome]. PMID- 4302832 TI - Nicotinamide deficiency and adrenocortical steroids. PMID- 4302833 TI - [Genetic characteristics of poliomyelitis strains isolated in Poland]. PMID- 4302834 TI - [Cancer of the gallbladder]. PMID- 4302835 TI - [A case of hemolytic anemia acquired through anti-erythrocyte autoantibodies (AEA) during chronic hepatitis]. PMID- 4302836 TI - Mesenteric nerve stimulation by intracarotid administration of angiotensin. PMID- 4302837 TI - Increased activity in sympathetic nerves induced by angiotensin. PMID- 4302838 TI - Hepatic extraction of angiotensin after carbon tetrachloride intoxication. PMID- 4302839 TI - [Rate of propagation of the sphygmic wave in the course of artificially induced hypertensive states]. PMID- 4302840 TI - [Studies on the disinfection of Enteroviruses in sewage. II. Inactivation of Poliomyelitis virus under the effect of combined availabe chlorine]. PMID- 4302841 TI - [The reaction of mitochondria to several damaging influences]. PMID- 4302842 TI - [Contribution to the study of experimental silicosis. I. Initial pulmonary changes produced by inhalation of silicious dust studies with optical and electron microscopes]. PMID- 4302843 TI - [Contribution to the study of experimental silicosis. II. Changes of the lung in rats exposed to prolonged inhalation of silicious dust studies with the electron microscope]. PMID- 4302844 TI - [Sterile and apyrogenic filtration]. PMID- 4302845 TI - [Angiosarcoma? Case for diagnosis]. PMID- 4302846 TI - [Stapolidex in dermatology]. PMID- 4302847 TI - [Abrikosov's tumor of the scalp]. PMID- 4302848 TI - [Value of combined quinacrine-aureomycin-corticotherapy in pemphigus: pemphigus vulgaris, followed for 8 years, cured at the present time; seborrheic pemphigus followed for 14 years with stabilization verging on cure]. PMID- 4302849 TI - [Angiofibroma in a cluster on the external ear]. PMID- 4302850 TI - [Photochemical and enzymatic reduction of flavodoxin isolated from Desulfovibrio gigas]. PMID- 4302851 TI - [Development of polyoma virus on explants of newborn mouse salivary glands]. PMID- 4302852 TI - [Histologic observations apropos of 2 cases of Masson's glomic tumors]. PMID- 4302853 TI - [On so-called cystic degeneration of peripheral nerve trunks]. PMID- 4302854 TI - [Age problems in neurosurgery]. PMID- 4302855 TI - [Cytotoxic action of quartz on macrophages and its prevention with synthetic polymers]. PMID- 4302856 TI - Effects of silica dust on some erythrocyte enzymes. PMID- 4302857 TI - [The method of solid-phase peptide synthesis]. PMID- 4302858 TI - [Hydrocyanic acid in the defense secretion of the earthrunner Pachymerium ferrugineum. XXXV. On arthropod defense substances]. PMID- 4302859 TI - Role of the liver in systemic puridine nucleotide metabolism. PMID- 4302860 TI - [Mammography in carcinoma of the breast. Radiological semeiotics]. PMID- 4302861 TI - [Hormones, nucleic acids and gene activity: new prospects in endocrinology]. PMID- 4302863 TI - [Immunological phenomena in chronicization of the hepatitis virus]. PMID- 4302862 TI - [Corticosteroid therapy in hepatic diseases]. PMID- 4302864 TI - [Sporadic adenoviral diseases in military personnel]. PMID- 4302865 TI - Mechanism of the musculotropic activity of angiotensin on the isolated guinea-pig seminal vsecile. PMID- 4302866 TI - Effects of some local anaesthetics on abnormalities of neuromuscular transmission produced by neostigamine in rats. PMID- 4302867 TI - On the bias of the distribution of the 2'-O-methylribonucleotide constituents of yeast transfer RNA. PMID- 4302868 TI - Low molecular weight RNA of the chromatin fraction from Novikoff hepatoma and rat liver nuclei. PMID- 4302869 TI - Electron microscopic study of the tertiary structure of covalently closed polyoma virus DNA. PMID- 4302870 TI - Transcription of the tryptophan operon of Escherichia coli in vitro. I. Detection and quantitative determination of specific RNA. PMID- 4302871 TI - Biosynthesis of tyrocidine by a cell-free enzyme system of Bacillus brevis ATCC 8185. II. Amino acid substitution in tyrocidine. PMID- 4302872 TI - The enzymic synthesis of adenylyl-(3'-5')-cytidine. PMID- 4302873 TI - Loganin from Mytragyna parvifolia Korth. PMID- 4302874 TI - [Interference microscopic study of medulloblastoma and glioblastoma cells]. PMID- 4302875 TI - The mode of formation of intracytoplasmic structures in tumours induced by viruses of the avian sarcoma leucosis group. PMID- 4302877 TI - Growth characteristics of axenic strains of Entamoeba histolytica Schaudinn, 1903. PMID- 4302876 TI - [Studies on the clinical and endocrinoligical significance of chorionic gonadotropins]. PMID- 4302878 TI - Subcellular distribution of enzymes in Ochromonas malhamensis. PMID- 4302879 TI - O2-polarographic studies on soluble and mitochondrial enzymes of Crithidia fasciculata; glycerophosphage enzymes. PMID- 4302880 TI - [An experiment in the treatment of malignant neoplasms with cyclophosphane]. PMID- 4302881 TI - [On the side-effects of ACTH in patients earlier subjected to long-term treatment with adrenal cortex hormones]. PMID- 4302882 TI - [On the functional state of the adrenal cortex during mitral defect of the heart]. PMID- 4302883 TI - [Factors influencing the effects of the antineoplastic action of antineoplastic agents. 3. Combined effects of mitomycin C and zymosan on tumors in rats]. PMID- 4302884 TI - Experimental induction of various kinds of tumors in ICR mice with cigarette tar. PMID- 4302885 TI - [Histopathologic peculiarities of the myoneuropathy caused by chloroquine diphosphate]. PMID- 4302886 TI - [Lymphography in cancer of the ovary. Observations on 37 cases]. PMID- 4302887 TI - [Mechanism of protein synthesis inhibition by antibiotics]. PMID- 4302888 TI - [FDPase and glycogen synthetase in liver cancer--comparison with enzymes of the liver and muscles]. PMID- 4302889 TI - [Cytochrome C peroxidase]. PMID- 4302890 TI - [Therapy of rheumatic fever]. PMID- 4302891 TI - [Short feedback mechanisms in the control of pituitary hormone secretion]. PMID- 4302892 TI - [Biological characteristics of synthetic ACTH]. PMID- 4302893 TI - [Metabolism of pituitary hormones in vivo]. PMID- 4302894 TI - [Chemical structure of pituitary hormones in the blood]. PMID- 4302895 TI - [Tests of anterior pituitary gland function]. PMID- 4302896 TI - [Common cold syndromes]. PMID- 4302897 TI - [Viral encephalitis]. PMID- 4302898 TI - [Enterovirus infections]. PMID- 4302899 TI - [Virus infections with exanthema]. PMID- 4302900 TI - [Congenital anomaly and virus infections]. PMID- 4302901 TI - [Effects of viral vaccines and related problems]. PMID- 4302902 TI - [Current problems in the application of ACTH]. PMID- 4302903 TI - [Experience in the use of iodopaste in diseases of the peripheral nervous system]. PMID- 4302904 TI - Effect of angiotensin II on urinary sodium excretion in normal subjects and in cirrhotic patients. PMID- 4302905 TI - The pharmacological actions of some guanidine esters and their relationship to tetrodotoxin. PMID- 4302906 TI - Synacthen depot. PMID- 4302907 TI - Japanese encephalitis studies in Vellore, South India. II. Antibody response of patients. PMID- 4302908 TI - Japanese encephalitis studies in Vellore, South India. 3. Neutralizing activity of human survey sera. PMID- 4302909 TI - Japanese encephalitis studies in Vellore, South India. IV. Search for virological and serological evidence of infection in animals other than man. PMID- 4302910 TI - Hepatoma in childhood. Report of two cases. PMID- 4302911 TI - Treatment of malignant brain tumors by local methotrexate. A preliminary report. PMID- 4302912 TI - Cushing's syndrome induced by the ectopic production of ACTH by a bronchial carcinoid. PMID- 4302913 TI - Growth hormone secretion during nocturnal sleep in normal subjects. PMID- 4302914 TI - Plasma 11-deoxycorticosteroid and ACTH response to metyrapone (plasma metyrapone test). PMID- 4302915 TI - Juvenile nasopharyngeal angiofibroma. Awareness in anesthesia of the juvenile nasopharyngeal angiofibroma. PMID- 4302916 TI - [Immuno-sero-epidemiological studies on Japanese encephalitis. I. Neutralizing and hemagglutination inhibition antibodies against Japanese encephalitis virus in healthy children from Kumamoto]. PMID- 4302917 TI - [Immuno-sero-epidemiological studies on Japanese encephalitis. II. Hemagglutination inhibition and neutralizing antibodies against Japanese encephalitis virus in slaughtered swine bred in various districts of Kumamoto prefecture, in 1966 and 1967]. PMID- 4302918 TI - Intestinal protozoa of the baboon Papio doguera Pucheran, 1856. PMID- 4302919 TI - [On pathogenesis and clinical course of meningeal lesions in influenza and influenza-like diseases]. PMID- 4302920 TI - [Tuberculostatic drugs of the second series. (Review of literature)]. PMID- 4302921 TI - [Increase of argentaffine cells of the duodenum of the guinea pig following intraperitoneal injection of angiotensin]. PMID- 4302923 TI - [The accident in old age]. PMID- 4302922 TI - [Stimulation of the adrenal gland by intramuscular by administered synacthen in various dosages]. PMID- 4302924 TI - [Postoperative and posttraumatic after care in old age]. PMID- 4302925 TI - Virus-induced diabetes in mice. PMID- 4302926 TI - Grand Rounds. Infantile cytomegalic inclusion disease vs. chronic gastrointestinal disturbances. PMID- 4302927 TI - The management of multiple sclerosis. II. Serial neurologic examinations and use of corticotropin and glucocorticoids. PMID- 4302928 TI - Skeletal renewal and metabolic bone disease. PMID- 4302929 TI - Effect of prlonged ACTH treatment on adrenal circulation in rats. PMID- 4302930 TI - Bilateral effects of skin stimulation on thalamic neurons. PMID- 4302931 TI - Prostaglandins: enzymatic analysis. AB - By, means of al specific nicotinamide-adeninie dinucleotide-dependent prostaglanidin dehydrogenase from swine lung, an enizymatic method has been developed for the assay of prostaglandins. The method permits analysis with a lower limit of 10(-12) mole of prostaglandin. PMID- 4302932 TI - [On changes of the hemoconcentration in the so-called progeria-like syndrome]. PMID- 4302933 TI - [Activity of phosphoprotein-phosphatase in the course of regeneration of liver of rats]. PMID- 4302935 TI - Ethyl silicate (tetraethyl orthosilicate, tetraethoxy silane) (C2H5)4-SiO4. PMID- 4302934 TI - Characterization and solubility of metals associated with asbestos fibers. PMID- 4302936 TI - Free silica (quartz) analysis by x-ray diffraction utilizing the pellet technique. PMID- 4302937 TI - Metronidazole in chronic intestinal amoebiasis. PMID- 4302938 TI - Sensitivity of microorganisms to antibiotics produced by them. PMID- 4302939 TI - Morphological and physiological investigations on the action of polymyxin B on Escherichia coli. PMID- 4302940 TI - Enzymic properties of a mutant of Escherichia coli K12 lacking nitrate reductase. PMID- 4302941 TI - Vitamin E-deficiency in the guinea pig: effect of succinate on mitochondrial nad linked oxidation. PMID- 4302942 TI - [The qualitative and quantitative composition of phospholipids in normal dog blood]. PMID- 4302943 TI - [Stimulation of viral multiplication by anti-interferon serum: influence on the number of plaques]. PMID- 4302944 TI - [Kinetics of development of Rous sarcoma virus (Schmidt-Ruppin strain). Estimation of maturation time by electron microscope autoradiography]. PMID- 4302945 TI - [Evidence for a specific repressor in the cells of different species transformed by SV 40 virus]. PMID- 4302946 TI - [Hormonal changes and clinical effects produced in patients treated with a delyed action preparation of synthetic ACTH]. PMID- 4302947 TI - [Parallelism between nephrocalcitopotropic and estrogenic activity of some anabolic steroids, androgens, progestational hormones and estrogens]. PMID- 4302948 TI - [Hereditary odontogenesis imperfecta]. PMID- 4302949 TI - The effect of nitrogen mustard on anaphylaxis in the pertussis-vaccinated mouse. PMID- 4302950 TI - Public health problems relating to the Vietnam returnee. PMID- 4302951 TI - The tarsal tunnel syndrome. Diagnosis and treatment. PMID- 4302952 TI - [Clinical studies of cochleotoxicosis due to viomycin and kanamycin during tuberculostatic treatment (a prophylactic attempt)]. PMID- 4302953 TI - [Cylindroma of the external ear canal]. PMID- 4302954 TI - [Inhibition of lipolysis in adipose tissue by methylisoxazolcarboxylic acids]. PMID- 4302955 TI - "Induction" of viral antigen in established cell line (SP-8) derived from Shope virus-induced cutaneous papilloma of rabbits. PMID- 4302956 TI - Prevalence of reticuloendotheliosis in chickens: immunofluorescence studies. PMID- 4302957 TI - Effect of statolon on acute and persistent murine leukemia and sarcoma virus infections. PMID- 4302958 TI - Experimental infection of rhesus with simian virus 40 (SV40). PMID- 4302959 TI - A comparison of the efficacy of endogenous, exogenous, and combined endogenous exogenous interferon in the treatment of mice infected with encephalomyocarditis virus. PMID- 4302960 TI - A rapid in vivo assay for SV40 tumor immunity in hamsters. PMID- 4302961 TI - Plasma 17-hydroxycorticosteroid response to ACTH in M. mulatta: dose, age, weight, and sex. PMID- 4302962 TI - Characterization of a cytomegalo-like virus isolated from spontaneously degenerated equine kidney cell culture. PMID- 4302963 TI - The effects of insulin on lipolysis evoked by cyclic AMP and its dibutyryl analog. PMID- 4302964 TI - [Remarks on the clinical value of the diagnosis of tumor cells in the cerebrospinal fluid. (Contribution to the question of an indication for surgery in malignant brain tumors]. PMID- 4302965 TI - [Clinico-therapeutic considerations on cephalic herpes zoster]. PMID- 4302966 TI - [Storage disease of medicamentous origin. Apropos of 5 cases. Histochemical and ultrastructural study]. PMID- 4302967 TI - [Paradoxical analogy of the effects on the renal circulation of hypertensive and hypotensive agents]. PMID- 4302968 TI - Ovarian tumours in children. Report of a rare case, a thecoma in a 12-year-old girl. PMID- 4302969 TI - [Associated aniridia and nephroblastoma]. PMID- 4302970 TI - [Thygeson's keratitis]. PMID- 4302971 TI - [Local administration of an anabolic hormone in ophthalmology]. PMID- 4302972 TI - [Vascular action of angiotensin: balance between peripheral vasoconstrictive influences and vasodilating influences of central origin]. PMID- 4302973 TI - [Influence of angiotensin on ganglionic transmission]. PMID- 4302974 TI - [Antagonism of vitamins A and D at the level of the lysosomes: study in mice in vivo]. PMID- 4302975 TI - [Development of glycolytic enzymes in the liver during the rat perinatal period]. PMID- 4302976 TI - [The improvement of the fit of model casts by influencing the expansion of the investment compound 'Modellgubeinbettmasse Law']. PMID- 4302977 TI - [Bronchiolo-alveolar carcinoma. (Clinico-anatomo-histological contribution)]. PMID- 4302978 TI - [Treatment of cancer of the liver by regional perfusion]. PMID- 4302979 TI - [Therapeutic indications in breast cancer excluding osseous and visceral metastases]. PMID- 4302980 TI - Survival rates in peripheral bronchogenic carcinomas up to four centimeters in diameter presenting as solitary pulmonary nodules. PMID- 4302982 TI - [Islet cell tumor]. PMID- 4302981 TI - [Data on the further study of the etiology and pathogenesis of hypertension]. PMID- 4302983 TI - [Peripheral nerve and muscle biopsy in various types of peripheral nerve diseases its diagnostic significance and its relationship to function]. PMID- 4302984 TI - Glucagon stimulation of adenyl cyclase activity of cardiac muscle. PMID- 4302985 TI - [Neurogenic tumors in rats following intraperitoneal application of N-nitroso-N methylurea]. PMID- 4302986 TI - In vitro passages of hamster tumour cells induced with Schmidt-Ruppin strain of Rous sarcoma viruse: their oncogenicity, morphology and karyology. PMID- 4302987 TI - Estrogens in the menopause and postmenopause. PMID- 4302988 TI - [Contribution on the problem of prevention and treatment of severe complications following the use of iodiene containing constrast media]. PMID- 4302989 TI - [Diagnosis, prophylaxis, treatment and after care of late pregnancy toxemias (E.P.H.-complex)]. PMID- 4302990 TI - [Prolonged post-traumatic coma and its characteristic polygraphic aspects]. PMID- 4302991 TI - [Methylmalonic aciduria. Study of its occurrence in clinical material]. PMID- 4302992 TI - In vivo study of the inflammatory basophilic responses in mucosal colitis and transmural colitis. PMID- 4302993 TI - [New antibiotics, with the exception of penicillins, streptomycin, tetracyclines and chloramphenicol]. PMID- 4302994 TI - The isolation of nucleic acids from gram-positive bacteria. PMID- 4302995 TI - Stereochemical studies on the microquantitative detection of vitamin D by gas liquid chromatography. PMID- 4302996 TI - Reaction mechanism and stereospecificity of 20 beta-hydroxysteroid dehydrogenase. PMID- 4302997 TI - On the fragmentation of mitochondria by diethylstilbesterol. II. On the relation of the released proteins to the mitochondrial membranes. PMID- 4302998 TI - Virus infections and respiratory disease of childhood. PMID- 4302999 TI - [Neuromuscular paralyzing action of saxitoxin]. PMID- 4303000 TI - Synacthen depot used in general practice. PMID- 4303001 TI - [Phospholipid ethers. Synthesis of dipalmityl-1,2-oxy-3-glyceryl phosphoric acid and dipyro(dipalmityl-1,2-oxy-3-glyceryl phosphoric) acid]. PMID- 4303002 TI - Time-course of enzyme adaptation. I. Effects of substituting dietary glucose and fructose at constant concentrations of dietary protein. PMID- 4303003 TI - Comparative mitochondrial function in two strains of Aspergillus niger. PMID- 4303004 TI - Isolation and characterization of antigenic components of rat glomerular basement membrane. PMID- 4303005 TI - An analysis of the lumbosacral dermatomes in man. PMID- 4303006 TI - [Significance of differential diagnosis of benign cholangioma and liver metastases]. PMID- 4303007 TI - Biochemical identification and characterization of the multiple forms of alkaline phosphatase in the developing duodenum of the mouse. PMID- 4303008 TI - [Recent data on the physiopathologic metabolism of aldosterone]. PMID- 4303009 TI - Skeletal maturation. PMID- 4303010 TI - Cancer-customs, habits and usages and environment. PMID- 4303011 TI - The riddles of cancer cells. PMID- 4303012 TI - Pathology of primary malignant neoplasms of the kidney. PMID- 4303013 TI - Malignant tumours of kidney. Clinical presentation. PMID- 4303014 TI - Malignant tumours of the kidney: diagnosis & surgical management. PMID- 4303015 TI - Radiation treatment in renal cancer: a review. PMID- 4303017 TI - Acute respiratory disease. PMID- 4303016 TI - Fibrous xanthoma of synovium (giant-cell tumor of tendon sheath, pigmented nodular synovitis). A study of one hundred and eighteen cases. PMID- 4303018 TI - Derangement of regional cerebral blood flow and of its regulatory mechanisms in acute cerebrovascular lesions. PMID- 4303019 TI - Working together. 3. PMID- 4303020 TI - Role of tissue histamine in reparative processes. PMID- 4303021 TI - [Clinical and therapeutic considerations on benign tracheo-bronchial tumors]. PMID- 4303022 TI - Preferred centripetal conduction of dendritic spikes in alligator Purkinje cells. AB - Dendritic action potentials in alligator Purkinje cells tend to have a unidirectional preference which favors centripetal over centrifugal propagation. This unidirectional tendency funnels the peripherally evoked dendritic spikes into the lower dendrites and soma of these cells, and it allows the peripheral dendritic branches to operate to a certain extent as partially independent functional units. PMID- 4303023 TI - Pituitary-adrenal influences on fear responding. AB - In a passive avoidance situation, hypophysectomized male rats show less fear than normal rats, whereas adrenalectomized rats show greater fear than normals. These results probably occur because hypophysectomized rats lack adrenocorticotrophic hormone, which increases arousal or emotionality, whereas adrenalectomized animals lack certain adrenal steroids, which inhibit excitatory effects. The results indicate that adrenocorticotrophic hormone and certain adrenal steroids have opposite effects in regulating fear-motivated behavior. PMID- 4303024 TI - Pituitary hormones: international colloquium. PMID- 4303025 TI - [Laryngeal fibro-angiomas as a diathetic manifestation]. PMID- 4303026 TI - A technique for the enzymatic diagnosis of glycogen storage disease on very small tissue specimens. PMID- 4303027 TI - Acute cerebellar ataxia associated with herpes simplex virus infection. PMID- 4303028 TI - [On the transmission of signals from stretch receptors to the dorsal spino cerebellar tract]. PMID- 4303029 TI - [States of wakefulness and sleep in neuro-endocrine regulation]. PMID- 4303030 TI - [Electrophysiological effects of adrenalectomy and adrenocortical hormones on the brain]. PMID- 4303031 TI - Contributions of EPR spectroscopy to our knowledge of oxidative enzymes. PMID- 4303032 TI - Enzymology of the nucleus. PMID- 4303033 TI - Extrinsic cotton effects and the mechanism of enzyme action. PMID- 4303034 TI - Control of aldosterone secretion by the renin-angiotensin system and by corticotropin. PMID- 4303035 TI - [Existence of capsulatum form histoplasmosis on the Ivory Coast. Description of first autochthonous human case with isolation of the strain]. PMID- 4303036 TI - Care in the balance. PMID- 4303037 TI - [On an acute anti-acetylcholine effect of hemicholinium no. 3 on the guinea pig atrium]. PMID- 4303038 TI - "Care in the balance". PMID- 4303039 TI - [The role and importance of lysosomes in pathology]. PMID- 4303040 TI - [A case of polyneuritis in the course of long-term treatment with nitrofurantoin]. PMID- 4303041 TI - [Microbiology of meat products. I. Microbiological study of manufactured meat products]. PMID- 4303042 TI - [Thecoma, granulosa cell carcinoma and arrhenoblastoma of the ovaries]. PMID- 4303043 TI - [Tumor of the posterior part of left temporal lobe with clinical picture of psychosis]. PMID- 4303044 TI - Cassava as food in Nigeria. PMID- 4303045 TI - Nucleic acids and protein synthesis in cancer cell mitochondria. I. Nucleic acids in rat hepatoma mitochondria. PMID- 4303046 TI - Anterior meningeal branch of the vertebral artery. PMID- 4303047 TI - Hepatoma presenting as extrahepatic biliary obstruction. Report of a case. PMID- 4303048 TI - Two new candidate enterovirus serotypes, isolated from CSF. PMID- 4303049 TI - The virus watch program: a continuing surveillance of viral infections in metropolitan New York families. VI. Observations of adenovirus infections: virus excretion patterns, antibody response, efficiency of surveillance, patterns of infections, and relation to illness. PMID- 4303050 TI - The titration of rhinoviruses and of antibodies against them by means of the photometric hemaggregation-inhibition test. PMID- 4303051 TI - Chromatographic separation of vitamins D2 and D3 and related compounds. PMID- 4303052 TI - Chromatography of vitamin A compounds on silicic acid columns. PMID- 4303054 TI - Determination of nucleoside composition of ribonucleic acid by gas-liquid chromatography. PMID- 4303053 TI - Chemical and ionization interferences in the atomic absorption spectrophotometric measurement of sodium, potassium, rubidium, and cesium. PMID- 4303055 TI - A method for colorimetric assay of inositol and some of its phosphate derivatives. PMID- 4303056 TI - Determination of nucleoside composition of ribonucleic acid by thin-layer chromatography. PMID- 4303057 TI - Rapid spectrophotometric assay for nicotinic acid. PMID- 4303058 TI - Electrophoresis of peptides on thin layers of silica gel. PMID- 4303059 TI - A polynucleotide ligase from polyoma virus-infected mouse cells. PMID- 4303060 TI - Immunological evidence for the absence of a polyoma virus-specific deoxyribonucleic acid polymerase. PMID- 4303061 TI - The localization of the neutral glycosphingolipids in rat liver cells. PMID- 4303062 TI - The incorporation of (14C) palmitate into glycerides and phospholipids of liver homogenates from fed and starved rats. PMID- 4303063 TI - Metabolism of vitamin D3 in man. PMID- 4303064 TI - Isomers of glucosaminylphosphatidylglycerol. PMID- 4303065 TI - The pyrophosphatase activity of pig kidney alkaline phosphatase and its inhibition by magnesium ions and excess of pyrophosphate. AB - 1. Pig kidney enzyme resembles other non-specific alkaline phosphatases in its ability to hydrolyse inorganic pyrophosphate (PP(i)). 2. Studies of enzyme velocity as a function of PP(i) concentration show that Michaelis-Menten kinetics are obeyed when a constant PP(i)/Mg(2+) concentration ratio is maintained, but velocity-substrate concentration curves are sigmoid when the concentration of PP(i) is increased but that of Mg(2+) is kept constant. The enzyme is inhibited when the total PP(i) concentration is greater than the total concentration of Mg(2+). Pyrophosphatase activity is activated by Mg(2+), but if the concentration of the metal ion is increased to a value in excess of the total PP(i) concentration Mg(2+) is then strongly inhibitory. 4. It appears that the enzyme is most active towards the complex ion MgPP(i) (2-). The enzyme probably hydrolyses PP(i) (4-) also, but this is a poorer substrate and its competition with MgPP(i) (2-) leads to inhibition. At high Mg(2+) concentrations Mg(2)PP(i) is formed. This complex appears to be a potent inhibitor. 5. Sigmoid plots of v against s and of v against i result from interactions occurring between Mg(2+) and PP(i) (4-) leading to MgPP(i) (2-) and Mg(2)PP(i), and are not indicative of allosteric behaviour. PMID- 4303066 TI - Continuous coupled assay for acetyl-coenzyme A production: correction of observed rates. PMID- 4303067 TI - The metabolism of thymol by a Pseudomonas. AB - 1. Pseudomonas putida when grown with thymol contained a meta-fission dioxygenase, which required ferrous ions and readily cleaved the benzene nucleus of catechols between adjacent carbon atoms bearing hydroxyl and isopropyl groups. 2. 3-Hydroxythymo-1,4-quinone was excreted towards the end of exponential growth and later was slowly metabolized. This compound was oxidized by partially purified extracts only when NADH was supplied; the substrate for the dioxygenase appeared to be 3-hydroxythymo-1,4-quinol, which was readily and non-enzymically oxidized to the quinone. 3. 2-Oxobutyrate (0.9 mole) was formed from 1 mole of 3 hydroxythymo-1,4-quinone with the consumption of 1 mole of oxygen; acetate, isobutyrate and 2-hydroxybutyrate (which arose from the enzymic reduction of 2 oxobutyrate) were also formed. 4. These products, which were produced only when the catechol substrate contained a third hydroxyl group, appeared to result from the enzymic hydrolysis of the ring-fission product. PMID- 4303068 TI - Soluble and insoluble phosphofructokinase in rat muscle. PMID- 4303069 TI - The effect of bilirubin on the human platelet. PMID- 4303070 TI - Shigella keratitis: a case report. PMID- 4303071 TI - Chronic granulomatous disease. PMID- 4303072 TI - Clinical staging of Wilms' tumor. PMID- 4303073 TI - Pagophagia and iron lack. PMID- 4303074 TI - Isolation of Japanese encephalitis virus from natural sources by means of plaque techniques in chick embryo monolayer cell cutlures. PMID- 4303075 TI - Long persistence of anti-dengue antibodies in the serum of native residents of some Japanese main islands. PMID- 4303076 TI - [Peripheral neuropathies in chronic kidney failure, in continous dialysis treatment and after kidney transplantation]. PMID- 4303077 TI - [Primary neuropathic amyloidosis, an unusual cause of steatorrhea]. PMID- 4303078 TI - [Secondary antitubercular drugs in the treatment of childhood tuberculosis]. PMID- 4303079 TI - Assay of plasma angiotensin. PMID- 4303080 TI - [On the pathogenesis and prognosis of serratus muscle paralysis]. PMID- 4303081 TI - Prostaglandin stimulation of rat corticosteroidogenesis. AB - Prostaglandins and their C20:(omega)6 fatty acid precursors are present in rat adrenal glands. Small doses of prostaglandins (PGE(1), PGE(2), or PGF(1infinity) 1.4 to 2.4 micromolar) increased steroidogenesis in the superfused adrenal glands obtained from hypophysectomized rats. This effect was mimicked in part by both adrenocorticotropin and its postulated intracellular intermediate adenosine 3', 5'-cyclic monophosphate; all three responses were inhibited by cycloheximide. PMID- 4303082 TI - [Molecular memory and coding of perception. II. Biologic and clinical data]. PMID- 4303083 TI - [Influence of monoamine oxidase inhibitors on the vasopressor activity of angiotensin. Experimental study]. PMID- 4303084 TI - [Experimental study of an intravascularly injectable solution of fatty acid esters of iodized poppyseed oil (A.G. 52-315)]. PMID- 4303085 TI - [Histologic study of the liver, spleen, kidney and lungs after injection of a solution of fatty acid ethyl esters of iodized poppyseed oil combined with surface-active agents (A.G. 52-315)]. PMID- 4303086 TI - [Malignant synovioma]. PMID- 4303087 TI - [Inactivation inhibition of ACTH by plasma albumin in vitro]. PMID- 4303088 TI - Involvement of suprahypothalamic structures in the hormonal feedback action of corticosteroids. PMID- 4303089 TI - Angiotensinase activity in blood plasma of the rat. PMID- 4303090 TI - The role of the liver in angiotensinogen production. PMID- 4303091 TI - Comparison of right atrial and right ventricular single and paired pacing in the canine heart. PMID- 4303092 TI - Mechanism of thiosulfate oxidation by Thiobacillus intermedius. PMID- 4303093 TI - Fructose 1,6-diphosphatase of rat tissues and transplantable rat hepatomas. PMID- 4303094 TI - A chick serum fraction that stimulates alkaline phosphatase activity in embryonic chick femora in culture. PMID- 4303095 TI - Exogenous NADH oxidation and particulate fumarate reductase in Mycobacterium phlei. PMID- 4303096 TI - Spin-labeling as a general method in studying antibody active site. PMID- 4303097 TI - The relation between membrane structure and NADH: (acceptor) oxidoreductase activity of erythrocyte ghosts. PMID- 4303098 TI - Terpene biosynthesis: formation of nerol, geraniol, and other prenols by an enzyme system from Pinus radiata seedlings. PMID- 4303099 TI - Nonheme iron protein as a possible site of rotenone inhibition of mitochondrial NADH dehydrogenase. PMID- 4303100 TI - Fructose diphosphatase from rabbit muscle. II. Amino acid composition and activation by sulfhydryl reagents. PMID- 4303101 TI - Immunological studies of liver, kidney, and muscle fructose 1,6-diphosphatases. PMID- 4303102 TI - Effects of D2O on the allosteric properties of bovine liver glutamic dehydrogenase. PMID- 4303103 TI - Calcification in a mucus-producing carcinoma of the stomach. Case report. PMID- 4303104 TI - The carinogenicity of N-hydroxy-N-2-fluorenyl-acetamide and the matabolism of N-2 fluorenyl-acetamide in Praomis (mastomys) natalensis. PMID- 4303105 TI - Distribution of a basic azo-dye-binding protein in normal rat tissues anc carcinogen-induced hepatomata. PMID- 4303106 TI - Rates of incorporation of tritium-labeled thymidine into the mitochondrial and nuclear DNA of normal rat liver, regenerating liver, and four hepatomas with different growth rates and their host livers. PMID- 4303107 TI - [Value of serology in the etiologic diagnosis of acute non-bacterial lung diseases in adults (apropos of 1047 cases)]. PMID- 4303108 TI - [Inhibition by Intensain of phosphodiesterease from rat hearts]. PMID- 4303109 TI - Signs of cerebral hypoxia in hyperventilation. PMID- 4303110 TI - The activity of neurons in the lateral geniculate body during wakefulness and natural sleep. PMID- 4303111 TI - Propagation of mouse hepatitis virus (MHV-3) in monolayer cell cultures from liver of newborn mice. PMID- 4303112 TI - [On the localization of estrogen production in the human placenta]. PMID- 4303113 TI - Combined action of Rous sarcoma virus and chemical carcinogen in rats. PMID- 4303114 TI - Chemical structure of circulin B. PMID- 4303115 TI - Hydrolysis of aminoacetonitrile: peptide formation. PMID- 4303116 TI - D-5-Chloro-2-(alpha-hydroxybenzyl) benzimidazole and 1-alkyl-5-chloro-2-(alpha hydroxybenzyl) benzimidazoles as inhibitors of poliovirus multiplication. PMID- 4303117 TI - Positive correlation of responsiveness to catecholamines of the rat liver glycogenolytic receptor with other alpha-receptor responses. PMID- 4303118 TI - [Lipiodol embolism following lymphography. (I. Clinical part)]. PMID- 4303119 TI - [A case of cerebral embolism following lymphography]. PMID- 4303120 TI - Report of the panel for the symposium on immunity to selected equine infectious diseases. PMID- 4303121 TI - Partial resection of the uterus for chorioadenoma destruens. PMID- 4303122 TI - Role of alkyl substitution in 2,3-disubstituted and 3-substituted 4-quinazolones on the inhibition of pyruvic acid oxidation. PMID- 4303123 TI - The synthesis and biological properties of some dibenzazepines and dibenzazonines related to protostephanine. PMID- 4303124 TI - Stimulation of the reticuloendothelial system in tumor-bearing rats. PMID- 4303125 TI - [Simultaneous occurrence of lung adenomatosis in mother and daughter]. PMID- 4303126 TI - [Lung embolism after lymphography with oily contrast media]. PMID- 4303127 TI - [Sarcoidosis of the nervous system]. PMID- 4303128 TI - Isolation and biochemical characteristics of the nuclear envelope. PMID- 4303129 TI - In vitro evidence of neutral collagenase activity in an invasive mammalian tumour. PMID- 4303130 TI - Relation between collagen synthesis and collagen proline hydroxylase activity in mammalian cells. PMID- 4303131 TI - Inhibition of rhinovirus by isatin thiosemicarbazone analogues. PMID- 4303132 TI - Dysfibrinogenemia in a patient with primary hepatoma. First observation of an acquired abnormality of fibrin monomer aggregation. PMID- 4303133 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 8-1969. PMID- 4303134 TI - Crohn's disease: natural history and treatment. PMID- 4303135 TI - The medical treatment of ulcerative colitis. PMID- 4303137 TI - [Trophoblastic tumors]. PMID- 4303136 TI - Nephropathy and viroses. PMID- 4303138 TI - [Effect of high doses of synthetic ACTH on the function of the hypothalamo hypophyseal-adrenal cortex system]. PMID- 4303139 TI - [Management of multiple sclerosis]. PMID- 4303140 TI - Care of the foaling mare and foal. PMID- 4303141 TI - [Recent data on the development of virus-induced tumors]. PMID- 4303142 TI - Quantitative histochemistry of hypothalamus. II. Thiamine pyrophosphatase, nucleoside diphosphatase and acid phosphatase in the activated supraoptic nucleus of the rat. PMID- 4303143 TI - Cytofluorometric study of mast cell polyanions. II. Adult rat peritoneal mast cells regenerating after polymyxin treatment. PMID- 4303144 TI - Primary malignancy of the liver in childhood. PMID- 4303145 TI - Infectious mononucleosis--a current concept and treatment. PMID- 4303146 TI - [Renin-angiotensin system in patients with circulatory insufficiency]. PMID- 4303147 TI - [Preliminary observations on the prognosis of recurrent herpes after specific vaccination]. PMID- 4303148 TI - [Considerations on an unusual clinical case of malignant mole]. PMID- 4303149 TI - [A comparative study of hepatic scanning and liver function tests]. PMID- 4303150 TI - [The state of adrenocorticotropic function of the pituitary and adrenal cortex in immobilization of the extremity and bone fracture during experiments]. PMID- 4303151 TI - [Debatable problems of aging of the skeleton]. PMID- 4303152 TI - [Sanitary conditions of the irregation waters of the orchands in the Sao Paulo district. II. Isolation of enteroviruses]. PMID- 4303153 TI - [The amebic abscess of the liver. Clinical and therapeutic aspects]. PMID- 4303154 TI - [Pharmacological inhibition and stimulation of ovulation]. PMID- 4303155 TI - [Amitotic cell division. An electronmicroscopical study on the adrenal cortex cells of Rana temporaria L]. PMID- 4303156 TI - [Multiple carcinomas of the gastrointestinal tract. (Large intestine polyposis and carcinogenesis)]. PMID- 4303157 TI - [Wilms' tumor in horseshoe kidney]. PMID- 4303158 TI - Rate of ethanol metabolism in fed and starved rats after thyroxine treatment. PMID- 4303159 TI - Collagenolytic activity in middle ear cholesteatoma. PMID- 4303160 TI - Isolation of virus from herpetic keratitis. Influence of idoxuridine on isolation rates. PMID- 4303161 TI - Theories and known observations about hormonal treatment of endometriosis-in situ, and endometriosis at the enzyme level. PMID- 4303162 TI - Activation of cardiac adenyl cyclase by thyroid hormone. PMID- 4303163 TI - Cloning of Burkitt lymphoma cells cultured in vitro. PMID- 4303164 TI - Adenosquamous carcinoma of the nasal, oral and laryngeal cavities. A clinicopathologic survey of ten cases. PMID- 4303165 TI - Primary Krukenberg tumor of ovary. Review of literature and case report. PMID- 4303166 TI - Ultrastructure of a hemangiopericytoma and a glomus tumor. PMID- 4303167 TI - Asymptomatic production of ACTH. Radio immunoassay in squamous cell, oat cell and adenocarcinoma of the lung. PMID- 4303168 TI - Some epidemiologic aspects of neoplastic diseases in Israeli immigrant population. 3. Brain tumors. PMID- 4303169 TI - Epidemiologic aspects of neoplastic diseases in Israeli immigrant population. II. Malignant neoplasms in childhood. PMID- 4303170 TI - Rhabdomyoma of larynx. Ultrastructural study and comparison with granular cell tumors(myoblastomas). PMID- 4303171 TI - Hepatoblastoma in the adult. PMID- 4303172 TI - Glomus tumors of the stomach. PMID- 4303173 TI - Elastofibroma--a degenerative pseudotumor. PMID- 4303174 TI - [Granular cell myoblastoma in the breast - pseudocarcinoma]. PMID- 4303175 TI - Medial and anterior tarsal tunnel syndrome. PMID- 4303176 TI - [Viruses and tumors]. PMID- 4303177 TI - The picodna viruses. H, RV, and AAV. PMID- 4303178 TI - The induction of cancer by combinations of viruses and other agents. PMID- 4303180 TI - The evaluation of left ventricular myocardial function in patients undergoing cardiac surgery. PMID- 4303179 TI - The use of cytotoxic drugs in the surgery of malignant disease. PMID- 4303181 TI - Cytomegalovirus mononucleosis following renal haemodialysis. PMID- 4303182 TI - [Treatment of brain edema with corticotropin hormone. (ACTH)]. PMID- 4303183 TI - [Colonic neoplasms in young subjects]. PMID- 4303184 TI - [Indications and methods of treatment in early scoliosis (apropos of 62 cases)]. PMID- 4303185 TI - The complications of Phisohex. PMID- 4303186 TI - [On the spectrophotometric study of the secondary structure of the nucleic acids in nucleoproteides]. PMID- 4303187 TI - Malignant mesenchymal tumours of the corpus uteri. PMID- 4303189 TI - Adenoid cystic carcinoma of the palate. PMID- 4303188 TI - [Histotopography of the enzymes related to carbohydrate metabolism and of uridine diphosphoglucose dehydrogenase in human epidermis]. PMID- 4303190 TI - Reflexes and their relationship to behavioural state in the newborn. PMID- 4303192 TI - [A very unusual case of tumor of the larynx. Unexpected anatomopathologic diagnosis]. PMID- 4303191 TI - Topical treatment of ulcerative mammary carcinoma by thiotepa compresses. PMID- 4303193 TI - [Giant cell tumor of the tendon sheaths. Apropos of 5 observations]. PMID- 4303194 TI - [Trophoblastic disease. Considerations on 40 cases observed in the Clinica Ostetrica e Ginecologica of the University of Sassari]. PMID- 4303195 TI - [Aminophenols as hydrocyanic acid antidotes]. PMID- 4303196 TI - K+ minus dependent phosphatase activity observed in the presence of both adenosine triphosphate and Na+. PMID- 4303197 TI - Simplification of mouse lactate dehydrogenase electrophoretic patterns. PMID- 4303198 TI - Citrate synthases: allosteric regulation and molecular size. PMID- 4303199 TI - The properties and subcellular distribution of phosphatidylinositol kinase in mammalian tissues. PMID- 4303200 TI - Chloride ion as a modifier of 2',3'-cyclic phosphodiesterase purified from halophilic Vibrio alginolyticus. PMID- 4303201 TI - The binding of ADP to myosin. PMID- 4303202 TI - On the nature of the free radical formed during the primary process of bacterial photosynthesis. PMID- 4303203 TI - Cytochrome oxidase and its derivatives. IX. Spectrophotometric studies on the rapid reaction of ferrous cytochrome c oxidase with molecular oxygen under conditions of complete and partial oxygenation. PMID- 4303204 TI - [Modification of the symptom of sensitivity to carbon dioxide conferred upon Drosophila by the vesicular stomatitis virus adapted to this insect (VSVD)]. PMID- 4303205 TI - [Cancerogenic power of urethane in Sprague rats]. PMID- 4303206 TI - [Study of chromosome aberrations during human viral diseases]. PMID- 4303207 TI - [Modifications by phenobarbital of the electric properties of neurons with a stable membrane potential (giant A neuron of Aplysia)]. PMID- 4303208 TI - [Effects of phenobarbital on the autoactive nuerons]. PMID- 4303209 TI - [Effect of imidazole on lipolysis of epididymal adipose tissue of white rats in vitro]. PMID- 4303210 TI - [Attempt to protect newborn hamster against polyoma tumor by repeated virus injections]. PMID- 4303211 TI - [Comparisons in vivo of the tritiated thymidine and uridine uptake by human normal and cancerous tissues]. PMID- 4303212 TI - Prostaglandins. PMID- 4303213 TI - [Comparative enzyme studies on snake venoms, with special reference to their casein-splitting proteases]. PMID- 4303214 TI - [Hepatic fribrocholanigiomatosis. Presentation of a case and considerations on its differential diagnosis extra-hepatic biliary obstruction]. PMID- 4303215 TI - Fluoride toxicity in the mouse. PMID- 4303216 TI - Immunofluorescence and cellular fraction studies on the multiplication of infectious canine hepatitis virus. PMID- 4303217 TI - Effect of sodium desoxycholate on infectious canine hepatitis virus, and an additional description of a small associated virus. PMID- 4303219 TI - Wilms' tumor metastiatic to mandible and oral mucosa. Report of a case. PMID- 4303218 TI - [Biological and clinical significance of isoenzymes in pediatrics]. PMID- 4303220 TI - [A further case of amyloid neuropathy]. PMID- 4303221 TI - Virus infections of the upper respiratory tract (abridged). PMID- 4303222 TI - Virus infections of the upper respiratory tract. PMID- 4303223 TI - Syndactyly and ring constrictions. PMID- 4303224 TI - [The significance of subtraction in neuroradiology]. PMID- 4303225 TI - Biogenic amines and the states of sleep. PMID- 4303226 TI - [Action of epsilon-aminocaroic acid in intolerance to contrast media containing organic iodine]. PMID- 4303227 TI - Pleuro-pulmonary amoebiasis. PMID- 4303228 TI - [Intrauterine developed scar on the back of an infant with multiple abnormalities]. PMID- 4303229 TI - Skeletal maturation of Danish school children in relation to height, sexual development, and social conditions. PMID- 4303230 TI - Actinomycin D and transverse lines of growing bones. PMID- 4303232 TI - [Studies on the production of anaerobic toxins. 2. Type A Clostridium perfringens toxin]. PMID- 4303231 TI - The influence of hormone treatment on the natural evolution of the idiopathic nephrotic syndrome in childhood. PMID- 4303233 TI - Corticotrophin secreetion capacity after long-term corticotrophin treatment in multiple sclerosis. PMID- 4303234 TI - [The chemical structure of the receptor substance active in the adsorption of TBE viruses on erythrocytes]. PMID- 4303235 TI - [Glutamate dehydrogenase in the photosynthetic bacterium Rhodospirillum rubrum]. PMID- 4303236 TI - The blink reflex as a diagnostic procedure. PMID- 4303237 TI - [Serological, virological and clinical investigations in an epidemic outbreak of adenovirus]. PMID- 4303238 TI - Pertussis vaccine research in the Rijks Instituut voor de Voklsgezondheid (the Netherlands). PMID- 4303239 TI - Antibodies to the group II lumpy skin disease viruses in the sera of cattle in Kenya. PMID- 4303240 TI - [On the reliability of the Hoyt-Morrison reaction in viral hepatitis (preliminary note)]. PMID- 4303241 TI - [On a case of cytomegalic disease with hypergamma M globulin]. PMID- 4303242 TI - [Corticotropic insufficiency of the arterior lobe of the pituitary gland in the infant]. PMID- 4303244 TI - Anti-SV-40 complement-fixing antibodies in the serum of children. PMID- 4303243 TI - [On the pathogenesis of the so-called malignant hypertension]. PMID- 4303246 TI - [Clinical characteristics of adenovirus diseases in military personnel]. PMID- 4303245 TI - [Responses of primary and secondary muscle spindle afferents to sinusoidal mechanical stimulation. II. Variation in the static component of the stimulus]. PMID- 4303247 TI - [Rapid determination of smallpox vaccine virus in tissue cultures by the method of fluorescent antibodies]. PMID- 4303248 TI - Histochemical studies of the cestode Diphyllobothrium dendriticum Nitzsch, 1824. PMID- 4303250 TI - Can nurses in general hospital participate in research. PMID- 4303249 TI - [Comparative histological, histochemical, and electron microscopical studies on lacrimal glands. I. Rabbit and cat]. PMID- 4303251 TI - The nursing role in a children's day hospital. PMID- 4303252 TI - Intervening when the patient is delusional. PMID- 4303253 TI - "Growth" and development. PMID- 4303254 TI - Antabuse program for alcoholics Racine County. PMID- 4303255 TI - International trends. PMID- 4303256 TI - Speaking out. On: the psychiatric aide, salaries and walk-out. PMID- 4303257 TI - Psychiatric drugs & trends. Guinea pigs behind bars. PMID- 4303258 TI - Use of punishment procedures in management of behavioral difficulties of the severely retarded. PMID- 4303260 TI - Technology and learning in nursing. PMID- 4303259 TI - [Nursing care of convalescent pediatric patients]. PMID- 4303261 TI - Toward rehabilitating the geriatric patient. PMID- 4303262 TI - Dynamics of change. PMID- 4303263 TI - Regional Medical Programs. PMID- 4303264 TI - Histological observations of cysticercus cyst walls of the liver of rats in relation to the precancerous stage in the Watanabe I tumor. PMID- 4303265 TI - Assessment of skeletal age in the first five years of life. PMID- 4303266 TI - Suppressed plasma renin activity in hypertension. PMID- 4303267 TI - Manipulation by corticotropin and cortisol of aldosterone secretion in primary aldosteronism. PMID- 4303268 TI - Combination chemotherapy in accelerated phase of chronic granulocytic leukemia. PMID- 4303269 TI - Endoplasmic reticulum and phenotypic variability in normal and neoplastic liver. PMID- 4303270 TI - [Ultrastructural changes in the zona fasciculata of the suprarenal gland of rats following ACTH administration]. PMID- 4303271 TI - [Ultrastructural study on progressive ocular muscular dystrophy with particular regard to mitochondrial transformation]. PMID- 4303272 TI - Histochemical studies on carbohydrate metabolism in the olfactory bulb of the rabbit. PMID- 4303273 TI - Dimensional changes of a cristobalite investment by heating, cooling and reheating. PMID- 4303274 TI - [Binding of proteohormones to plasma proeins]. PMID- 4303275 TI - [Arterial aneurysm and intracraneal arteriovenous angioma]. PMID- 4303276 TI - Peripheral compression lesions of the ulnar nerve. PMID- 4303277 TI - Spontaneous paralysis of the anterior interosseous nerve. PMID- 4303278 TI - The arcade of Frohse and its relationship to posterior interosseous nerve paralysis. PMID- 4303279 TI - A search for the causes of severity in smallpox. PMID- 4303280 TI - Surgical treatment of diseases of salivary glands. PMID- 4303281 TI - Granular cell myoblastoma occurring in the upper lip: report of case. PMID- 4303282 TI - [Epidemiological and clinical study of primary cancer of the liver with special reference to a nation-wide survey]. PMID- 4303283 TI - [Electron microscopic findings of Paget's disease]. PMID- 4303284 TI - [Case of pulmonary alveolar epithelioma]. PMID- 4303285 TI - [Repeated surgery in cancer of the large intestine]. PMID- 4303286 TI - [Surgical therapy of cancer of the rectum (analysis of 600 operations)]. PMID- 4303287 TI - [On early diagnosis of lung cancer]. PMID- 4303288 TI - [Cancer of the thyroid gland in light of the experience of the surgeon and morphologist]. PMID- 4303289 TI - [Some problems of surgery of stomach cancer]. PMID- 4303290 TI - Acute respiratory infections in aircrew under training with special reference to influenza and adenovirus infections. PMID- 4303291 TI - Effects of nervous system lesions on phantom experience in amputees. PMID- 4303292 TI - [Findings on ovarian tumors with endocrine activity]. PMID- 4303293 TI - [Autopsy case of thorotrast-induced liver cancer complicated by thyroid cancer]. PMID- 4303294 TI - [Gas gangrene septicemia. 2 cases with intravascular hemolysis and protracted shock]. PMID- 4303295 TI - Isopycnic separation of subcellular components from poliovirus-infected and normal HeLa cells. AB - A rapid method for determining the density of ribonucleoprotein particles and complexes has been developed. The method involves glutaraldehyde fixation of sucrose gradient fractions and immediate centrifugation for 5 hours through preformed cesium chloride gradients. There is little or no aggregation of particles, so that components which co-sediment in sucrose gradients are resolved by the cesium chloride gradient. By this method the densities of HeLa cell ribosomes, polyribosomes, and subribosomal particles have been determined. Furthermore, the poliovirus replication complex has been separated from polyribosomes and its density has been found to be unaffected by treatment with ethylene-diaminetetraacetic acid. PMID- 4303296 TI - Histone phosphorylation: stimulation by adenosine 3',5'-monophosphate. AB - Adenosine cyclic 3',5'-monophosphate at a concentration of 10-(7)M causes a four to sixfold increase in the rate of histone phosphorylation catalyzed by a liver enzyme preparation. This observation suggests a mechanism for the induction of RNA synthesis by those hormones that cause increases in the concentration of cyclic AMP. PMID- 4303297 TI - [The use of morphocycline in experimental anaerobic infection]. PMID- 4303298 TI - [Evaluation of the functional state of the adrenal cortex in patients with epydermophytosia of feet]. PMID- 4303299 TI - [Acute adrenal insufficiency cuased by discontinuation of corticosteroid treatment]. PMID- 4303300 TI - Colistin sulfate versus sodium colistimethate. PMID- 4303301 TI - Vasopressin test in an adrenocorticotrophic-hormone-producing tumor. PMID- 4303302 TI - Vasopressin test in an adrenocorticotrophic-hormone-producing tumor. PMID- 4303303 TI - Cranial mononeuropathy as the first sign of intracranial metastases. PMID- 4303304 TI - Congenital adrenal hyperplasia secondary to 17-hydroxylase deficiency. Two sisters with amenorrhea, hypokalemia, hypertension, and cystic ovaries. PMID- 4303305 TI - Experimental dietary hepatoma in rainbow trout. The role of cottonseed meals and other diets. PMID- 4303306 TI - [Medullary carcinoma, oncocytoma and parastruma in the framework of epithelial neoplasms of the thyroid. Histological and histogenetic study]. PMID- 4303307 TI - [Epidemic of pharyngoconjunctival fever in a youth camp caused by adenovirus type 3]. PMID- 4303308 TI - [Share of adenoviruses in respiratory tract diseases in a group of children observed for a long time]. PMID- 4303309 TI - Reflex regulation of arterial pressure during sleep in man. A quantitative method of assessing baroreflex sensitivity. PMID- 4303310 TI - Fine structural localization of acetylcholinesterase at a cholinergic vasodilator nerve-arterial smooth muscle synapse. PMID- 4303311 TI - [Statistically defined control of fowl pox vaccinations]. PMID- 4303312 TI - [The occurrence of mycoplasma and virus antibodies in chicken with and without diseases of the respiratory system]. PMID- 4303313 TI - Tissue response to intraperitoneal asbestos with preliminary report of acute toxicity of heart-treated asbestos in mice. PMID- 4303314 TI - [The natural radioactivity and solubility of dust containing silicon]. PMID- 4303315 TI - Kinetics of NAD reduction in the nucleus and the cytoplasm. PMID- 4303316 TI - [1-0-alpha-glucopyranosyl-(1-2)-0-alpha-D-glucopyranosyl-glycerol from the glycolipids of streptococcus faecalis and Streptococcus lactis]. PMID- 4303317 TI - Alk-1-enyl ethers of glycerol and thanediol. PMID- 4303318 TI - [Crystallization and biochemical properties of glycerol-3-phosphate dehydrogenase from human liver]. PMID- 4303319 TI - On the localization of poly ADPribose synthetase in the nucleus. PMID- 4303320 TI - [Studies on the biosynthesis of cyclitols. XXI. An enzyme system capable of phosphorylating myo-inositol to phytic acid]. PMID- 4303321 TI - A serologic study on some respiratory viral and rickettsial infections in a rural community. PMID- 4303322 TI - Astereognosis not of cortical origin. PMID- 4303323 TI - Effects on ACTH release, of intrapituitary injections of posterior pituitary hormones and several amines in the hypothalamus. PMID- 4303324 TI - Role of catecholamine and adenosine in the ischemic response following release of a renal artery occlusion. PMID- 4303325 TI - A simplifiel method for the preparation of high titer polyoma virus. PMID- 4303326 TI - Electron microscopic study of virus particles in experimentally mixed tumor cells. PMID- 4303327 TI - Various antibody holding status against viruses in Cercopithecus aethiops and Macaca irus. I. The presence of neutralizing antibodies to measles virus and polio virus. PMID- 4303328 TI - Various antibody holding status against viruses in Cercopithecus aethiops and Macaca irus. II. The presence of neutralizing antibody against herpes virus, ECHO virus and simian virus 40. PMID- 4303329 TI - The use of beta-propiolactone and ultraviolet irradiation for the treatment of viral contamination of canine serum. PMID- 4303331 TI - Neurological diseases in Korea. PMID- 4303330 TI - [Ultrasonics in complex treatment of patients witn tuberculosis]. PMID- 4303332 TI - Absorption studies in neurological disorders. PMID- 4303333 TI - Peripheral neuropathy and carcinoma. PMID- 4303334 TI - A malignancy involving the cranial nerves with a possible geographic distribution. PMID- 4303335 TI - [Oxidation of carbohydrates by periodic acid]. PMID- 4303336 TI - [Primary carcinoma of the small intestine. (Case reports)]. PMID- 4303337 TI - [On hereditary infantile spinal amyotrophias. Genetic, histochemical and ultrastructural aspects]. PMID- 4303338 TI - [Immunoelectrophoretic properties of adenovirus antigens]. PMID- 4303340 TI - [Detection of the antigen of Rous sarcoma virus (strain no. 6) in a culture of chick fibroblasts by the fluorescent antibody technique]. PMID- 4303339 TI - [A study of the plaque-forming activity of monkey papovavirus SV40 (OV40)]. PMID- 4303341 TI - [Use of leukocyte cultures for studying cytomegalovirus infection in man]. PMID- 4303342 TI - [Immunofluorescent detection of a specific surface antigen in cells infected or transormed by polyoma virus]. PMID- 4303343 TI - [Use of organ cultures in the study of respiratory viruses (preliminary report)]. PMID- 4303344 TI - [Cytadsorption reaction]. PMID- 4303345 TI - [Clinical, laboratory diagnostic, electrophonocardiographic, and roentgenologic studies with consideration of the ACTH-test in Moller-Barlow's disease and of acropachy in the dog. II. Acropachy]. PMID- 4303348 TI - The thoracic glanglia of the grasshopper, Melanoplus differentialis: fine struc- ture of the perineurium and neuroglia with special reference to the intracellular distribution of phosphatases. PMID- 4303347 TI - Pituitary vascularity and ACTH release in rats with hypothalamic lesions. PMID- 4303349 TI - [Comparative histollgical, histochemical and electron microscopic studies on the lacrimal gland. II. Goats]. PMID- 4303350 TI - Influence of some streptomyces antibiotics on the inner ear of the guinea pig. Electrophysiological and histological study. PMID- 4303351 TI - [Test for oxytetracycline hydrochloride (Tetran R) in oculentum oxytetracycline formula mumber IV preparation]. PMID- 4303352 TI - [Results of cooperative clinical study of the new antineoplastic antibiotic, bruneomycin]. PMID- 4303353 TI - [Change in the sensitivity to antibiotics of pathogenic staphylococci, isolated in Tiflis during 1961-1966]. PMID- 4303354 TI - [Ristomycin A and B. Structure of the carbohydrate part of the molecule]. PMID- 4303355 TI - [Development of resistance of Mycobacterium tuberculosis to cycloserine, ethionamide, kanamycin, florimycin in experiments in vitro]. PMID- 4303346 TI - A review of neuroendocrinology, 1966-67. PMID- 4303357 TI - [Industrial hygiene and toxicology studies with hydrophobe amorphous silicic acids II. Precipitating silicic acid D 500]. PMID- 4303356 TI - [Levomycetin and tis combinations with other drugs in the treatment of abdominal typhus]. PMID- 4303358 TI - [The anaerobic flora of the natural cavities of the human body. I. A simple method for the isolation of Cl. perfringens from the intestine]. PMID- 4303359 TI - [Serological, virological and clinical diagnosis of sporadic cases of adenovirosis]. PMID- 4303360 TI - The deposition and metabolism of polyphosphoinositides in rat and guinea-pig brain during development. AB - 1. The deposition of triphosphoinositide and diphosphoinositide in rat and guinea pig cerebral hemispheres during growth was measured. 2. The maximum increase in concentration of both of these phospholipids occurs during the period of myelination, but in the rat some di- and tri-phosphoinositide is present before significant myelination begins. 3. In guinea-pig cerebral hemispheres the polyphosphoinositides remaining after post-mortem breakdown are selectively enriched in dissected white matter compared with grey matter. 4. The polyphosphoinositides in the cerebral hemispheres of rats were labelled with injected (32)P very rapidly; the specific radioactivities were in the order triphosphoinositide>diphosphoinositide>monophosphoinositide>total lipid phosphorus. 5. The synthesis of triphosphoinositide in rat forebrain occurs at an appreciable rate before, and at the start of, myelination, but the amount formed per gram of tissue is four to five times greater in adult rat brains, thus maintaining a constant turnover time (about 1hr.) for the whole triphosphoinositide fraction. This indicates that the rapid turnover of triphosphoinositide is independent of myelin deposition. 6. The specific radioactivity of the brain acid-soluble phosphorus pool referred to a constant dose of (32)P/g. body wt. falls rapidly with age, reaching a minimum at 13-14 days, and then rises again. The specific radioactivities of the polyphosphoinositides reflect this change. 7. Part of the polyphosphoinositides in rat and guinea-pig cerebral hemispheres is rapidly hydrolysed post mortem leaving a stable portion resistant to further breakdown. 8. The rate and extent of post-mortem hydrolysis of the polyphosphoinositides in both species decrease with age. 9. After (32)P labelling, the specific radioactivity of the triphosphoinositide remaining in the cerebral hemispheres of the rat after post mortem breakdown is lower than the original triphosphoinositide fraction, suggesting two metabolically distinct pools. PMID- 4303361 TI - The metabolism of polyphosphoinositides in hen brain and sciatic nerve. AB - 1. The distribution of individual phospholipids was determined in hen brain and compared with that in sciatic nerve obtained in a previous investigation. Sciatic nerve is more enriched in the myelinic phospholipids ethanolamine plasmalogen, phosphatidylserine and sphingomyelin, but it contains relatively less triphosphoinositide, and much less diphosphoinositide, than the brain. 2. The course of incorporation of intraperitoneally injected (32)P into the acid-soluble phosphorus, phosphoinositides and total phospholipids of hen brain and sciatic nerve was followed. Although the maximum specific radioactivity in sciatic nerve of acid-soluble phosphorus is 4.5 times, and that of triphosphoinositide six times, that in the brain, the relative rate of triphosphoinositide phosphorus synthesis per gram of brain is three times that in sciatic nerve. 3. Administration of the demyelinating agent tri-o-cresyl phosphate to hens has no significant effect on the amounts or the rate of (32)P incorporation into the total phospholipids of the sciatic nerve. However, the rate of incorporation of (32)P into triphosphoinositide, although not its concentration, is raised from the first day after administration of the drug and remains thus 13 and 23 days later. 4. The incorporation of (32)P into polyphosphoinositides of hen brain slices in vitro was studied. The recovery of triphosphoinositide from the slices is markedly increased in the presence of EDTA, although the rate of incorporation of (32)P is unaffected. The incorporation of (32)P is dependent on the presence of Mg(2+) and Ca(2+) in the medium, and is decreased when Na(+) is replaced with K(+) or cholinium ions. PMID- 4303362 TI - Gluconeogenesis in developing rat kidney cortex. AB - 1. Gluconeogenesis in developing rat kidney cortex was studied by assaying the activities of two enzymes, glucose 6-phosphatase and phosphoenolpyruvate carboxykinase, and by measuring glucose formation in tissue slices. 2. Glucose 6 phosphatase and phosphoenolpyruvate carboxykinase are present in late foetal (21 22-day-old) tissue and increase rapidly postnatally. Maximum activity of phosphoenolpyruvate carboxykinase occurs at 7 days of age, followed by a decline to the adult level. Glucose 6-phosphatase activity rises during the first 2 postnatal weeks and then declines. 3. Late foetuses synthesize glucose from both pyruvate and l-glutamate. The rate increases during the first 2 weeks to above adult levels. Synthesis is always higher from pyruvate than from glutamate. 4. The effect of 24hr. starvation was studied in perinatal animals. The results indicate that the ability to increase the rate of glucose synthesis as a result of starvation is not present at birth, but develops some time after the second postnatal day. PMID- 4303363 TI - Lactate dehydrogenase isoenzymes of sperm cells and tests. AB - 1. The kinetic and metabolic properties of lactate dehydrogenase isoenzyme LDH(x) from human sperm cells and rat testes were studied. 2. LDH(x) shows a sensitivity to inhibition by stilboestrol diphosphate, urea and guanidinium chloride different from that of the LDH-H(4) and LDH-M(4) isoenzymes. 3. About 10 and 20% of the total lactate dehydrogenase activity of testes and sperm cells respectively were associated with particulate fractions. In sperm cells 11% was localized in the middle piece and 18.8% in the head fraction. LDH(x) was found in all particulate fractions of sperm cells. The middle piece contained 41.0% of total LDH(x) activity and showed high succinate dehydrogenase activity. 5. The pH dependence of lactate/pyruvate and NAD(+)/NADH concentration ratios were estimated. Lactate dehydrogenase in sperm cells has maximal activity with NADH as coenzyme at pH7.5 and with NADPH as coenzyme at pH6.0. At pH6.0 a 10% greater oxidation of NADPH than of NADH was found. At acid pH lactate hydrogenase may function as an enzyme bringing about transhydrogenation from NADPH to NAD(+). 6. In agreement with the stoicheiometry of the lactate de- hydrogenase reaction, the lactate/pyruvate concentration ratio decreased with increasing pH. 7. The lactate/pyruvate and NAD(+)/NADH concentration ratios were estimated with glucose, fructose and sorbitol as substrates and as a function of time after addition of these substrates. During a 20min. period after the addition of the substrates, changes in lactate/pyruvate and NAD(+)/NADH concentration ratios were noticed. Increasing concentration of the substrates mentioned gave rise to asymptotic increases in lactate and pyruvate. 8. Sorbitol did not act as a substrate for LDH(x). 9. The findings described are consistent with the idea that LDH(x) is different from other known lactate dehydrogenase isoenzymes, but that it has a metabolic function similar to that of the isoenzymes of other tissues. PMID- 4303364 TI - The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans. PMID- 4303365 TI - [Diagnostic practice in intestinal malabsorption]. PMID- 4303366 TI - Characteristic and selective aggregate-forming activity of neoplastic cells in culture. PMID- 4303367 TI - Electron spin resonance study on the interaction between the chemical carcinogens and tissue components. 3. Determination of the structure of the free radical produced either by stirring 3,4-benzopyrene with albumin or incubating it wtih liver homogenates. PMID- 4303368 TI - Effect of growth of rhodamine sarcoma in rat on some liver enzyme activities. PMID- 4303369 TI - Cytological individuality of hepatoma cell lines derived from a single Donryu rat. PMID- 4303370 TI - The distribution of thiamine diphosphate-phosphohydrolase in the neurosecretory nuclei of the rat following osmotic stress. PMID- 4303372 TI - [Aspiration of mucus or smear for bacteriological identification of B. pertussis?]. PMID- 4303371 TI - [Contribution to the histochemistry of lactate dehydrogenase]. PMID- 4303373 TI - [The problem of ulcerations of the mouth in general medicine with special reference to herptico-herpetiform lesions]. PMID- 4303374 TI - [Syndrome of hypersplenism in the course of adenosplenic tuberculosis. Illustration of an unusual case]. PMID- 4303375 TI - [Serological and epidemiological studies of cytomegaloviruses]. PMID- 4303376 TI - [On the thermal resistance of C. perfringens, an agent of alimentary poisoning. I. Technics of demonstration in feces]. PMID- 4303377 TI - A review of psychoendocrine research on the pituitary-adrenal cortical system. PMID- 4303378 TI - Urinary androsterone, etiocholanolone, and dehydroepiandrosterone responses to 72 hr. avoidance sessions in the monkey. PMID- 4303379 TI - "Over-all" hormonal balance as a key to endocrine organization. PMID- 4303380 TI - "Intracerebral steal" in man recorded by a heat clearance technique. PMID- 4303381 TI - Biochemical basis of tissue acidosis. PMID- 4303382 TI - [Renal insufficiency in decompensated liver cirrhosis. Report of 5 cases and a review of the pathophysiology]. PMID- 4303383 TI - [Cytomegalovirus and cytomegaly. A review and a preliminary report of our results]. PMID- 4303384 TI - [Cytomegalic inclusion disease. A review and a case report]. PMID- 4303385 TI - [3 cases of acquired cytomegalic virus infection]. PMID- 4303386 TI - [Data on the study of adenovirus infection in chronic tonsillitis]. PMID- 4303387 TI - [Nobel prizes for John F. Enders, Frederick Ch, Robbins and Thomas H. Weller in 1954 for discovery of the possibility of growing poliomyelitis virus on various tissue media]. PMID- 4303388 TI - [Methods for the determination of renin activity in plasma]. PMID- 4303389 TI - [Micromethod for the enzymatic determination of acetoacetic acid and D-(-)-beta hydroxybutyric acid in blood and tissues]. PMID- 4303390 TI - [On cathepsin and phosphoprotein phosphatase in the soluble fraction from mouse and rat brain tissue]. PMID- 4303391 TI - [Comparative histological, histochemical, and electron-microscopical studies on lacrimal glands. 3. Sheep]. PMID- 4303392 TI - [Communication on the etiology of viral diseases. 4th quarter and yearly review 1967. II]. PMID- 4303393 TI - [Corticosteroid hormones in the treatment of chronic lympholeukosis]. PMID- 4303394 TI - Booster effect of oral poliovaccine. Trials in persons previously immunized with inactivated vaccine. PMID- 4303395 TI - Enzymatic conversion of phenylpyruvate to phenylacetate. PMID- 4303396 TI - Aminopropanol dehydrogenase activity in rat-liver preparations. PMID- 4303397 TI - The enthalpy change in the hydrolysis of the phosphate esters of myo-inositol. PMID- 4303398 TI - Metabolism of 2,3-diphosphoglycerate and glycolysis in humna red blood cells under the infleucne of dipyridamole and inorganic sulfur compounds. PMID- 4303399 TI - Perodate oxidation, pKa and conformation of hexuronic acids in polyuronides and mucopolysaccharides. PMID- 4303400 TI - ACTH release by purified hypothalamic CRF preparation as assayed by intrapituitary microinjection. PMID- 4303401 TI - [Intracellular distribution of acid exonuclease in rat liver]. PMID- 4303402 TI - Rubredoxin from a nitrogen-fixing variety of Desulfovibrio desulfuricans. PMID- 4303403 TI - 3 alpha-hydroxysteroid: NAD oxidoreductase activity in crystalline preparations of 20 beta-hydroxysteroid: NAD oxidoreductase. PMID- 4303404 TI - [Participation of the pituitary-adrenal system in the synthesis and release of catecholamine in the adrenal medulla]. PMID- 4303405 TI - [Interrelation between adrenal cortical and medullary secretion]. PMID- 4303406 TI - [Relation between the pituitary-adrenal system and the adrenal medulla]. PMID- 4303407 TI - [Electron microscopic studies on the relation between the adrenal cortex and medulla in rats]. PMID- 4303408 TI - Genetics of octanol dehydrogenase in Drosophila metzii. PMID- 4303409 TI - [Experimental studies and clinical experieces with linocomycin]. PMID- 4303410 TI - Differential effects of hypothalamic deafferentation on responses to different stresses. PMID- 4303411 TI - Effects of steroid hormones on drug-metabolizing enzyme systems in liver microsomes. PMID- 4303412 TI - Glycosyl glycerides from Streptococcus hemolyticus strain D-58. PMID- 4303413 TI - On the deoxyribonucleases, K1 and K2, isolated from mycelia of Aspergillus oryzae. I. Isolation and purification of DNases K1 and K2. PMID- 4303414 TI - The two deoxyribonucleases, K1 and K2, isolated from mycelia of Aspergillus oryzae. II. Determination of 5'- and 3'-termini of the DNA fragments produced by DNases K1 and K2. PMID- 4303415 TI - Quantitative determination of Clostridium welchii phospholipase C activity in aqueous reaction medium. PMID- 4303416 TI - Application of the isotope dilution method to microanalytical determination of five classes of sphingoglycolipids in tissues. I. Preparation and properties of tritium labelled sphingoglycolipids. PMID- 4303417 TI - Interaction between normal and transformed bovine fibroblasts in culture. II. Cells transformed by polyoma virus. PMID- 4303418 TI - Use of field modulation with boxcar integrator to measure relaxation time in electron spin resonance experiments. PMID- 4303419 TI - Inhibition of interferon production by chloroquine diphosphate. PMID- 4303420 TI - On some problems of complications in the central nervous system due to vaccination. PMID- 4303421 TI - Interference phenomenon in the culture of chick embryo cells infected with Schmidt-Ruppin strain of Rous sarcoma virus. PMID- 4303422 TI - Cytomegalovirus infection in children in Japan. PMID- 4303423 TI - Enhanced replication of Newcastle disease virus in cell culture co-infected with certain other viruses. PMID- 4303424 TI - [Physio-psychological study on sleep, with special reference to the electroenephalogram]. PMID- 4303425 TI - [Cerebrospinal fluid changes in patients with tumours of the cerebral hemispheres]. PMID- 4303426 TI - [Chiari's disease and the Budd-Chiari syndrome]. PMID- 4303427 TI - [On evoked myography in pelvic pain and sciatica]. PMID- 4303428 TI - [Case of multiple glomus tumor in the right lower limb]. PMID- 4303429 TI - Disseminated intravascular coagulation in the newborn. PMID- 4303430 TI - [Isolation of the virus of cytomegalic inclusion disease in children with different diseases]. PMID- 4303431 TI - [Carotid-cavernous fistula in a boy. Embolization with lipiodol-wax]. PMID- 4303432 TI - [Changes of the electroencephalographic pattern of spontaneous nocturnal sleep in circulatory disorders of the pons and medulla oblongata]. PMID- 4303433 TI - Comparison of the pressor activity and the renin content of the renal venous effluent in patients suspected of suffering from surgically remediable hypertension. PMID- 4303434 TI - Further studies on renal lesions of New Zealand black (NZB-BL) strain mice. PMID- 4303435 TI - [Paget's disease localized in the vulva]. PMID- 4303436 TI - [Position of zoonoses among infectious diseases from the epidemiological viewpoint]. PMID- 4303437 TI - [Experimental studies on the method of in vitro lipolysis]. PMID- 4303438 TI - Responses to steroids of Xiphophorus ACTH cells in organ culture. PMID- 4303439 TI - Non-specific esterase in cerebral tumors. A histochemical study. PMID- 4303440 TI - [Local application of Polymyxin B for gram-negative infections in urology]. PMID- 4303441 TI - Visual form agnosia. A specific defect in visual discrimination. PMID- 4303442 TI - Trichloroethylene neuropathy. PMID- 4303443 TI - Concentration by Diaflo ultrafiltration of murine leukemia and sarcoma viruses grown in tissue cultures. PMID- 4303444 TI - Studies of the significance of tumor antigens in induction and repression of neoplastic diseases: presidential address. PMID- 4303445 TI - Electron microscopy of the irises of chickens with spontaneous ocular leukosis. PMID- 4303446 TI - Enzymes of thymidine triphosphate synthesis in selected Morris hepatomas. PMID- 4303447 TI - Morphologic and biologic characteristics of the canine cutaneous histiocytoma. PMID- 4303448 TI - Central cholinergic pathways. PMID- 4303449 TI - Behavioral aspects of cholinergic transmission. PMID- 4303450 TI - Invited discussion: postreinforcement synchronization and the cholinergic system. PMID- 4303451 TI - Is the central cholinergic nervous system overexploited? PMID- 4303453 TI - Central cholinergic transmission and its behavior aspects. Introductory remarks. PMID- 4303452 TI - Application of control systems theory to physiology. Adrenal glucocorticoid control system. PMID- 4303454 TI - Central cholinergic transmission and its behavioral aspects. Historical introduction. PMID- 4303455 TI - Significance of acetylcholinesterase in central synaptic transmission. PMID- 4303456 TI - Acceleration of liver cell proliferation in vitro by N-nitrosodimethylamine. PMID- 4303457 TI - Renal metabolic response to acid base changes. I. Enzymatic control of ammoniagenesis in the rat. AB - Experiments were done on rats to investigate the nature of the renal response to metabolic acidosis and the changes in enzyme activity associated with increased ammoniagenesis. When metabolic acidosis was induced with oral feeding of ammonium chloride for 48 hr, there was an increase of activity of the enzyme phosphoenolpyruvate carboxykinase (PEPCK) in whole kidneys as well as in the kidney cortex. There was no change in PEPCK in liver, and glucose-6-phosphatase showed no change in kidney or liver in response to metabolic acidosis. The increase in PEPCK activity in kidney cortex varied with the degree of acidosis and there was a close correlation between cortical PEPCK activity and urinary ammonia. Kidney cortex mitochondrial PEPCK did not change in response to metabolic acidosis. An increase in PEPCK occurred as early as 6 hr after NH(4)Cl feeding, before there was any increase in kidney glutaminase I activity. Rats fed sodium phosphate, or given triamcinolone intramuscularly, developed a metabolic alkalosis, but there was increased urinary ammonia and an increase in activity of renal cortical PEPCK. Triamcinolone plus ammonium chloride induced a greater increase of PEPCK activity than triamcinolone by itself; on the contrary, the rise of glucose-6-phosphatase induced by triamcinolone was not enhanced by acidosis. Glucose-6-phosphatase from control and acidotic rats had identical kinetic characteristics. The results indicate that increased PEPCK activity is constantly related to increases of urinary ammonia. It is proposed that the increase of PEPCK activity is the key event in the ammoniagenesis and gluconeogenesis which follow on metabolic acidosis. PMID- 4303458 TI - Studies on phenolic steroids in human subjects. 8. Metabolism of estriol-16 alpha-glucosiduronate. AB - 6,7-(3)H-Estriol-16alpha-glucosiduronate-(14)C was administered to eight women (nine studies) by several routes: both injection and infusion (300 min) into the cubital vein, injection into the portal vein system, ingestion and instillation into the duodenum, jejunum, and ileum. Urine, collected from 0-2, 2-4, 4-8, 8-12, and 12-24 hr, was analyzed by countercurrent distribution for its content of radioactive 3- and 16-glucosiduronate (E(3)-3Gl,E(3)-16Gl) and sulfoglucosiduronate (E(3)-3S,16Gl) of estriol as well as for (3)H/(14)C ratio of each conjugate. After peripheral injection 50-60% of the injected E(3)-16Gl was excreted unchanged along with about 5% as E(3)-3S,16Gl with an unchanged (3)H/(14)C ratio, indicating direct sulfation of the injected E(3)-16Gl. During a 300 min infusion, urinary excretion closely resembled that following injection. But 2-4 hr after the end of the infusion excretion of E(3)-3S, 16Gl stopped, excretion of E(3)-3Gl (17%/24 hr) with an elevated (3)H/(14)C ratio started, and excretion of E(3)-16Gl continued (70%/24 hr), but with a rapidly increasing (3)H/(14)C ratio. This indicated sequestration in a sluggishly metabolizing compartment where two processes occurred: (a) extensive hydrolysis of E(3)-16Gl followed by reconjugation at either C3 or C16 with unlabeled uridine diphosphate glucuronic acid (UDPGA), thereby increasing the (3)H/(14)C ratio; and (b) transconjugation from C16 to C3, thereby producing E(3)-3Gl with finite (3)H/(14)C ratios. Instillation into various segments of the small intestine produced results qualitatively similar to those after intravenous infusion, whereas ingestion and intraportal injection resembled peripheral intravenous injection. Therefore, we have postulated the possibility of an enteric circulation (in addition to an enterohepatic circulation) in which the steroid or its conjugates are transported into the small intestine in the succus entericus, modified, and then reabsorbed and excreted in the urine-a process which requires several hours. PMID- 4303459 TI - Studies on phenolic steroids in human subjects. IX. Role of the intestine in the conjugation of estriol. AB - In order to compare the enteric circulation of estriol-16alpha-glucosiduronate (see preceding paper) with that of estriol (E(3)), labeled estriol was administered to six women by several routes: both injection and infusion (300 min) into the cubital vein, injection into the portal vein system, ingestion and instillation into the jejunum and ileum. Urine, collected from 0-2, 2-4, 4-8, 8 12, and 12-24 hr, was analyzed by countercurrent distribution for its content of radioactive 3- and 16-glucosiduronate (E(3)-3Gl,E(3)-16Gl) and sulfoglucosiduronate (E(3)-3S,16Gl) of estriol. After peripheral injection of E(3), E(3)-16Gl was excreted rapidly and E(3)-3S,16Gl at a slower and more constant rate. E(3)-3Gl was barely detectable after infusion. After injection of E(3) into the portal vein, the excretion of E(3)-3S,16Gl was greater and quicker than after peripheral injection. Even in a subject with a complete bile fistula, the urinary excretion of E(3)-3S,16Gl was essentially unchanged. Ingestion also produced the same result. Only after instillation into the ileum was a large and rapid excretion of E(3)-3Gl obtained, whereas the excretion of E(3)-3S,16Gl, and E(3)-16Gl were depressed. These results together with those of the preceding paper suggest that E(3) does not readily appear in the small intestine except via a hepatoenteric circulation that produces very little E(3)-3Gl. When present in the distal segment of the small intestine, however, absorption, conjugation, and elimination proceed readily. PMID- 4303460 TI - Ventricular function in noncardiacs with alcoholic fatty liver: role of ethanol in the production of cardiomyopathy. AB - Since many patients with cardiomyopathy have a history of chronic ethanolism often associated with malnutrition, we have evaluated left ventricular (LV) function in alcoholics with fatty liver, who had no clinical evidence of cardiac or nutritional disease. During an afterload test of LV function the pressor response to angiotensin evoked a threefold rise of enddiastolic pressure in the alcoholic group which was substantially greater than the 4 mm Hg rise in control subjects. The stroke volume and stroke work response in the noncardiac alcoholic was significantly less than in controls. Diminished LV function was corroborated in the noncardiac alcoholic at rest, using a contractility index. To evaluate the dose-response relationship of ethanol in the production of cardiac malfunction, two groups of noncardiac alcoholic subjects were studied acutely at low and moderate dose levels. After 6 oz, ventricular function, myocardial blood flow, and metabolism were not significantly affected. After 12 oz, there was a progressive rise of end-diastolic pressure and decrease of stroke output at a mean blood alcohol level of 150 mg/100 ml, reverting toward control by 4 hr. The coronary effluent transiently evidenced leakage of cell constituents, despite an increase of coronary blood flow, suggesting a direct but reversible cardiac injury. Myocardial extraction of triglyceride was enhanced, whereas FFA uptake was reduced. A possible role of myocardial triglyceride accumulation in heart muscle was considered in pathogenesis. Chronic ingestion of 16 oz of Scotch daily by an alcoholic subject while on a normal diet produced, after 12 wk, a progressive increase of heart rate and size, circulation time, and venous pressure, and a ventricular diastolic gallop. Normal values were restored within 7 wk after interrupting alcohol. These several studies suggest that the cumulative effects of repeated ingestion of ethanol in intoxicating doses can produce diminished LV function before clinical evidence of cardiac abnormality, or heart disease not necessarily related to malnutrition. PMID- 4303461 TI - [Clinical studies on preventive chemotherapy after removal of hydatidiform mole]. PMID- 4303462 TI - Studies of the zeta potential of cells and a silica particle in varying concentrations of albumin, calcium, sodium, plasma, and bile. PMID- 4303463 TI - Glomus tumor simulating nerve root compression and Raynaud's phenomenon. Case report. PMID- 4303464 TI - Solitary intramedullary carcinomatous metastasis in the spinal cord. Case report. PMID- 4303465 TI - Cytochemistry of sea urchin gametes. 3. Acid and alkaline phosphatase activity of spermatozoa and fertilization. PMID- 4303466 TI - Inhibition of angiotensinases in the rat plasma and kidney. PMID- 4303467 TI - Studies on parainfluenza virus infections among infants and children in Sendai. I. Isolation and identification methods of parainfluenza viruses. PMID- 4303468 TI - A new cell line of calf kidney and its susceptibility to viruses. PMID- 4303469 TI - Interference with virus infection induced by RNA in chick embryo cells. PMID- 4303470 TI - Studies on parainfluenza virus infections among infants and children in Sendai. II. Serologic and epidemiologic investigation. PMID- 4303471 TI - Effect of actinomycin-D on DNA synthesis in African green monkey kidney cultures uninfected and infected with SV40. PMID- 4303472 TI - Effect of corticotropin and adrenocortical hormone on the blood flow through brown adipose tissue in the rat. PMID- 4303473 TI - Inactivation and mutagenesis due to the photodynamic action of acridines and related dyes on extracellular bacteriophage T4B. PMID- 4303474 TI - Sleep cycle characteristics in infants. PMID- 4303475 TI - Proton magnetic resonance studies of human cyanomethemoglobin. PMID- 4303476 TI - The transcription of the SV40 genome in productively infected and transformed cells. PMID- 4303477 TI - Human cell strains susceptible to focus formation by human adenovirus type 12. PMID- 4303478 TI - The role of the lac promotor locus in the regulation of beta-galactosidase synthesis by cyclic 3',5'-adenosine monophosphate. PMID- 4303480 TI - The mechanism of the pyruvate, phosphate dikinase reaction. PMID- 4303479 TI - Interaction of aminoacyl transferase II and guanosine triphosphate: inhibition by diphtheria toxin and nicotinamide adenine dinucleotide. PMID- 4303481 TI - Conformational properties of polyformycin: a polyribonucleotide with individual residues in the syn conformation. PMID- 4303482 TI - Biological activity of 25-hydroxycholecalciferol, a metabolite of vitamin D3. PMID- 4303483 TI - Morphological and histochemical properties of the regenerated mucosa in the ileum of the rat. PMID- 4303484 TI - Drug induced inhibition of fibrin stabilization. PMID- 4303485 TI - Basic science and pancreatic surgery. A study in anatomy, physiology and pathology. PMID- 4303486 TI - Pitfalls in the diagnosis of pneumonia. PMID- 4303487 TI - Pneumonia in childhood. PMID- 4303488 TI - The effect of actinomycin D on the transcription and replication of simian virus 40 deoxyribonucleic acid. PMID- 4303489 TI - In vitro products of a membrane-free foot-and-mouth disease virus ribonucleic acid polymerase. PMID- 4303490 TI - Viropexis of vesicular stomatitis virus by L cells. PMID- 4303491 TI - Kinetics of neutralization of sensitized herpes simplex virus with antibody fragments. PMID- 4303492 TI - [Pelvic arteriography in evaluation of trophoblastic pathology]. PMID- 4303493 TI - Metastasizing nasopharyngeal angiofibroma. A case report. PMID- 4303494 TI - Maxillary sinus angiofibroma treated with cryosurgery. PMID- 4303495 TI - Conjoint family therapy for alcoholics. PMID- 4303496 TI - Effects of DNA on free radical production from the carcinogens 4-nitro-and 4 hydroxyamino-quinoline 1-oxides in aqueous medium at 77 degrees K. PMID- 4303497 TI - Influence of particle size on physicochemical properties of pharmaceutical powders. VII. Fluidity and packing property of binary mixtures. PMID- 4303498 TI - [Purification of HCG from the normal villi and trophoblastic tumor and the comparison of their biochemical characteristics]. PMID- 4303499 TI - [Endocrinological studies on the hormone milieu of chorionic tumor patients. 1. Chorionic gonadotropin and nucleic acid levels in normal pregnancy and chorionic tumor]. PMID- 4303500 TI - [Endocrinological studies on the hormone milieu of chorionic tumor patients. 2. Study on delta-5-3-beta-hydroxysteroid dehydrogenase activity and endocrinological analysis of chorionic tumor patients]. PMID- 4303501 TI - Kalafungin, a new broad spectrum antibiotic. Isolation and characterization. PMID- 4303502 TI - Mycophenolic acid: antiviral and antitumor properties. PMID- 4303503 TI - Studies on the EPR and light absorption spectra of horse erythrocyte catalase and its derivatives. PMID- 4303504 TI - Purification and properties of ascorbate oxidase from cucumber. PMID- 4303505 TI - The purification of prenyltransferase and isopentenyl pyrophosphate isomerase of pumpkin fruit and their some properties. PMID- 4303506 TI - Oxidation and reduction of copper proteins: note added to the previous report on the state and activity of copper atoms in copper proteins. PMID- 4303507 TI - [Myoblastoma of the laryns or Abrikossof's tumor]. PMID- 4303508 TI - [ACTH secretion mechanism--experimental study]. PMID- 4303509 TI - [Mixed tumors]. PMID- 4303510 TI - Antiviral activity of selected Catharanthus alkaloids. PMID- 4303511 TI - A glucose-responsive insulinoma. PMID- 4303513 TI - A case of Klippel-Weber syndrome. PMID- 4303512 TI - Acute lymphocytic leukemia in children: maintenance therapy with methotrexat administered intermittently. Acute Leukemia Group B. PMID- 4303514 TI - [Study on polymyxin B]. PMID- 4303515 TI - [Treatment of malignant tumors in infants with antineoplastic agents]. PMID- 4303516 TI - [Chemotherapy of brain tumors]. PMID- 4303517 TI - Experimental bronchopneumopathy due to SO2 in the dog. PMID- 4303518 TI - [Use of different types of ACTH in the evaluation of patients with hypophyseal tumors. Findings in 28 cases]. PMID- 4303519 TI - Histochemical demonstration of glycogen synthetase in the normal human epidermis. PMID- 4303520 TI - Fatty acid composition of cerebrosides and cerebroside sulphatides in cerebral oedema. PMID- 4303521 TI - Potentiation by smooth muscle stimulants of the hypogastric nerve--vas deferens preparation from normal and castrated guinea-pigs. PMID- 4303522 TI - Abnormal estrogen responses to ACTH stimulation in the polycystic ovary syndrome. PMID- 4303523 TI - Studies on antigens from axenically cultivated Entamoeba histolytica and Entamoeba histolytica-like amebae. PMID- 4303524 TI - Studies on parainfluenza type 2 and 4 viruses obtained from patients with common colds. AB - Four agents which were obtained from adults with common colds were cultivated and identified-one was influenza type B and the others were parainfluenza viruses of types 2 and 4. Their cultivation was assisted by the use of organ cultures of human embryo tracheal or nasal epithelium. They infected and caused typical common colds in volunteers. PMID- 4303525 TI - Studies on lipoic acid uptake by bacteria. 3. Intracellular distribution of enzymes. PMID- 4303526 TI - The in vitro product of poliovirus polymerase. PMID- 4303527 TI - Inhibition by adrenocorticotrophin of gonadotrophin-induced ovulation in immature female rats. PMID- 4303528 TI - Adenosine 3',5'-monophosphate (cyclic AMP) as the mediator of the actions of melanocyte stimulating hormone (MSH) and norepinephrine on the frog skin. PMID- 4303529 TI - Morphology and hormone production of rat hypophyseal and adrenocortical tissue in tissue culture. PMID- 4303530 TI - Effect of chlorpropamide on the permeability of the urinary bladder of the toad and the response to vasopressin, adenosine-3',5'-monophosphate and theophylline. PMID- 4303531 TI - Growth hormone and phosphorylase activity in adipose tissue. PMID- 4303532 TI - Effect of high sodium intake on the response of the rat adrenal to angiotensin II. PMID- 4303533 TI - Lingually induced inhibition of masseteric motoneurones. PMID- 4303534 TI - Inhibitory effect of immune serum on carcinogenesis in mice neonatally infected with murine sarcoma virus (Harvey). PMID- 4303535 TI - Interaction of Rous sarcoma virus with rat embryo fibroblasts of inbred Lewis strain in vitro. PMID- 4303536 TI - Labelled tocopherols in man. Intestinal absorption and thoracic-duct lymph transport of dl-alpha-tocopheryl-3,4-14C2 acetate dl-alpha-tocopheramine-3,4-14C2 dl-alpha-tocopherol-(5-methyl-3H) and N-(methyl-3H)-dl-gamma-tocopheramine. PMID- 4303537 TI - Enzyme activity and immunoelectrophoretic pattern in the guinea pig in avitaminosis C. PMID- 4303538 TI - Studies on adenylylstreptomycin, a product of streptomycin inactivation by E. coli carrying the R-factor. PMID- 4303539 TI - The structure of the guanido amino acid moiety of viomycin. PMID- 4303540 TI - Mechanism of action of phenomycin: comparative study with diphtheria toxin. PMID- 4303542 TI - Electron microscopic studies on mode of action of polymyxin. PMID- 4303541 TI - Fractionation and characterization of the plasma and mesosome membrane of Listeria monocytogenes. AB - Protoplasts of Listeria monocytogenes strain 42 were fractionated after control lysis on a Ficoll (a polysucrose) density gradient. Visually, five zones could be recognized in the gradient. The first one was composed of amorphous cytoplasmic solutes (fraction 1a) and a mixture of particles (fraction 1b). These were: (i) light particles that were lipase-sensitive and composed of six subunits and (ii) heavy particles, sensitive to ribonuclease and devoid of fine structure. The second zone consisted of tubules and vesicles still harboring cytoplasmic components (fraction 2), whereas the third zone contained only empty vesicles and protoplast ghosts (fraction 3). The material congregating into the fourth zone was morphologically identical to that of the third (fraction 3a). The fifth and heaviest zone contained a mixture of (i) particles without any substructure and (ii) partly lysed protoplasts (fraction 4). Fractions 1b and 4 were the richest in nucleic acids (ribonucleic acid, 11.4 and 9.4%, respectively; deoxyribonucleic acid, 5.1 and 4.8%, respectively), whereas fraction 1b had the highest protein contents (74.6%). Phospholipids were mainly found in fractions 2 and 3. Except for fraction 1, all materials contained significant amounts of protein-bound phosphorus. The main concentrations of four enzymes were: glucose-6-phosphate dehydrogenase (fraction 1a); adenosine triphosphatase and reduced nicotinamide adenine diphosphate oxidase (fraction 3); nitro blue tetrazolium chloride reductase (fraction 2). Fractionation of strain 42 after addition of (32)P during the mid-log phase of growth revealed that the radio-activity was mainly detected in fraction 1b, when growth in the presence of the marker was allowed for 10 min, and in fraction 2, when growth was allowed for 90 min. The vesicles of fraction 2, often tubular, are probably of mesosomal origin, whereas those of fraction 3, which are always spherical, represent, most likely, the bulk of the cell plasma membrane. Our data showed slight chemical differences between these two fractions, but the differences in enzymatic activities and lipid-phosphorus incorporation during long pulse experiments were most dramatic. PMID- 4303543 TI - Acquired cytomegalovirus infection and retardation of somatic growth. PMID- 4303544 TI - The effect of theophylline on amine-induced cardiac phosphorylase activation and cardiac contractility. PMID- 4303545 TI - Drinking caused by the intracranial injection of angiotensin into the rat. PMID- 4303546 TI - [Basic and clinical studies of muscle relaxants]. PMID- 4303547 TI - [Hydrocortisone level in the blood of patients with mitral stenosis in connection with surgical intervention]. PMID- 4303548 TI - Lung function studies after the intralymphatic injection of emulsions of ethiodol in dogs. PMID- 4303549 TI - The influence of anti-inflammatory drugs on the glycoprotein biosynthesis in vitro. PMID- 4303550 TI - A practical method for the fractionated fluorimetric estimation of estrogens in pregnancy urine. PMID- 4303551 TI - The detection of androsta-4,16-dien-3-one in peripheral plasma of adult men. PMID- 4303552 TI - The role of human fetal adrenals in steroidogenesis: effect of adrenocorticosterone on urinary excretion of estrogens in pregnancy. PMID- 4303553 TI - [Isolation of mitochondria and yolk structures from fish embryos]. PMID- 4303554 TI - [The para-influenza virus infection in infancy. Virological, serological and clinical studies]. PMID- 4303555 TI - Fever therapy in aestival conjunctivitis. PMID- 4303556 TI - [The auriculotemporal syndrome]. PMID- 4303557 TI - [Allergy and synthetic ACTH]. PMID- 4303558 TI - Isolated adrenocorticotrophic hormone deficiency in acute intermittent porphyria. PMID- 4303559 TI - [Broncho-alveolar carcinoma]. PMID- 4303560 TI - [Sudden unilateral vestibular diseases]. PMID- 4303561 TI - [On so-called non-chromaffin paraganglioma of soft tissues. Case contribution]. PMID- 4303562 TI - Studies on the biosynthesis of nicotinamide adenine dinucleotide (NAD) in mammals and its regulatory mechanism. II. PMID- 4303563 TI - An agar disc method for testing the sensitivity of microorganisms to antibiotics. PMID- 4303564 TI - Effect of prostaglandin E-1 (PGE-1) on the vascular responsiveness to norepinephrine and angiotensin in the anesthetized rat. PMID- 4303565 TI - [Antimicrobial effect of potential isothiocyanate components. 4]. PMID- 4303566 TI - [Histological and enzyme-histochemical investigations of rat kidneys after polyvinylpyridine-N-oxide (PVNO)]. PMID- 4303567 TI - Extracellular unit recording from the thalamus in chronically implanted patients with movement disorders. PMID- 4303568 TI - [Angioplethysmographic and arteriographic research in a case of subungual glomus tumor]. PMID- 4303569 TI - [Enzyme histochemical demonstration of the fresh myocardial infarction in cases of suspected violent death]. PMID- 4303570 TI - [On the problem of corroborative significance of finding diatoms in the greater circulatory system]. PMID- 4303571 TI - [Influence of blood alcohol on diatom findings in drowned bodies]. PMID- 4303572 TI - Hydrocephalus as a sequela of experimental myxovirus infections. PMID- 4303573 TI - Changes of phenylalanyl-tRNA of Morris hepatoma 5123 revealed by reverse phase chromatography. PMID- 4303574 TI - [Contribution to the x-ray diagnosis of "cylindromas" of the maxillary region]. PMID- 4303575 TI - [Significance of mammography as a mass-screening technic in tumor detection. 1st results in 1080 examined women]. PMID- 4303576 TI - [On secondary carcinoma in the remaining breast following radical breast surgery]. PMID- 4303578 TI - Studies with the radioimmunoassay for angiotensin II, and its application to measurement of renin activity. PMID- 4303577 TI - Retrobulbar blockade in Endotoxin and horse-serum induced uveal response in rabbits. PMID- 4303579 TI - Stimulation and suppression of aldosterone secretion in patients with an aldosterone-producing adenoma. PMID- 4303580 TI - Plasma dehydroepiandrosterone sulfate in normal and pathological conditions. PMID- 4303581 TI - Role of renin in adaptation to sea water in euryhaline fishes. PMID- 4303582 TI - [On the problem of reinervation of the heart]. PMID- 4303583 TI - [On the therapy of herpes simplex keratitis with heparin and trypsin]. PMID- 4303584 TI - [Type and distribution of viral particles in primary and transplanted mammary neoplasms in mice (R3-Dm-Se)]. PMID- 4303585 TI - [Titration of Rhinopneumonitis equorum virus in vitro cultures using an indicator virus]. PMID- 4303586 TI - [Behavior of some enzymes in the blood during acute ethylism]. PMID- 4303587 TI - [Contraction of collagen in NaCLO4 solution]. PMID- 4303588 TI - [On the carcinogenic effect of N-nitrosohexamethyleneimine]. PMID- 4303589 TI - [Effect of clinical exacerbations and ACTH therapy on the level of lipids in blood serum of patients with sclerosis]. PMID- 4303590 TI - [A case of bilateral paralysis of peroneal nerve in luminal poisoning]. PMID- 4303591 TI - [Results of treatment of embryonal nephroma (Wilms's tumor)]. PMID- 4303592 TI - [Multiple acute duodenal ulcers during oral corticoid therapy]. PMID- 4303593 TI - [Defects of oncogenic viruses]. PMID- 4303594 TI - [Resistance of viruses of the subgroup smallpox-vaccinia to treaments primarily damaging the protein coat of the nucleic component of the virus]. PMID- 4303595 TI - [Isolation of oncogenic viruses of the papovavirus group by the mixed culture method]. PMID- 4303596 TI - [Specific soluble antigen in normal and malignant tissues containing the mammary gland cancer virus]. PMID- 4303597 TI - [Phenotypic manifestations of various genetic characteristics of herpes simplex virus in relation to conditions of culturing]. PMID- 4303598 TI - [On the joint effect of interferon and histone on the cytopathic effect of vesicular stomatitis virus]. PMID- 4303599 TI - [Contribution on the etiology of intrahepatic bile duct cysts]. PMID- 4303600 TI - [Bronchiolo-alveolar carcinoma. (Physiopathological, experimental and clinical contribution to the study of so-called malignant pulmonary adenomastosis)]. PMID- 4303601 TI - Effect of corticotrophin and cortisone on the incorporation of 3H-thymidine into the deoxyribonucleic acids (DNA) of the regenerating liver in the white rat. PMID- 4303602 TI - Hypothalamo-pituitary-adrenal response during major surgical stress. PMID- 4303603 TI - Pituitary-adrenal function in patients given long-term adrenal steroid therapy. PMID- 4303604 TI - Congenital ocular anomalies in 800 mentally deficient patients. PMID- 4303605 TI - [Effect of vibration on the functional state of the adrenal cortex]. PMID- 4303606 TI - Effect of corticotropin on gastric acid, pepsin, and mucus secretion in dogs with fistulas. PMID- 4303607 TI - Ulceration of intramural gastric neoplasms. PMID- 4303608 TI - [Histoenzymology of the endocrine pancreas treated by biguanidine in the guinea pig]. PMID- 4303609 TI - [Histochemical study of the intestinal mucosa in children. I. The normal duodeno jejunal mucosa]. PMID- 4303610 TI - [Histochemical study of the intestinal mucosa in children. II. Celiac disease]. PMID- 4303611 TI - [Histochemical research on the activity of carbohydrate enzymes in adipose tissue]. PMID- 4303612 TI - [ATP-ase activity in various types of artery]. PMID- 4303613 TI - Effect of an erotic movie on the sleep and dreams of young men. PMID- 4303614 TI - Blood pressure changes during EEG-monitored sleep. A comparative study of hypertensive and normotensive Negro women. PMID- 4303615 TI - [Serological study of foot-and-mouth disease virus strains in the Middle East]. PMID- 4303616 TI - [Comparatve serological and immunological study of strains of foot-and-mouth disease virus type "O" isolated in Europe between 1963 and 1966]. PMID- 4303617 TI - [Typing of foot-and-mouth disease virus. World Reference Laboratory for Foot-and Mouth Disease, Pirbright, Great Britain. Quarterly Cumulative Report]. PMID- 4303618 TI - [Typing of the foot-and-mouth disease virus. Nong-Sarai (Thailand)]. PMID- 4303619 TI - [Republic of the Ivory Coast. Law No. 63-328 of 29th July 1963, on sanitary regulations regarding animals in the Ivory Coast]. PMID- 4303620 TI - [2 cases of severe amniotic constriction]. PMID- 4303621 TI - [Meningeal forms of cerebral tumors]. PMID- 4303622 TI - [Epidemiology of poliomyelitis in Senegal]. PMID- 4303623 TI - [Skin reaction of healthy pregnant women and women with late toxemia to angiotensin II]. PMID- 4303624 TI - Activation of adenyl cyclase by glucagon in cat and human heart. PMID- 4303625 TI - [Phosphodiesterase I. Specific proof after disk electrophoresis and occurrence in plants]. PMID- 4303626 TI - Enzyme histochemical reactions of mouse ova. PMID- 4303627 TI - Interaction of cocaine with angiotensin and tyramine on the isolated rabbit aortic strips. PMID- 4303628 TI - Actions of interferon in tissue cultures harboring mouse leukemia virus. PMID- 4303629 TI - Differentaiation in vitro of chick embryo adrenal glands. PMID- 4303630 TI - [Synaptic mechanisms of vestibulo-spinal influences on alpha-motoneurons]. PMID- 4303631 TI - [Effect of bromide on spinal postsynaptic inhibition]. PMID- 4303632 TI - Role of adenovirus in the causation of acute respiratory disease in Egypt. PMID- 4303633 TI - [Study on the determination of nucleus DNA in chorionic cancer using microspectrophotometry]. PMID- 4303634 TI - [Study on the fluctuation of urinary pregnandiol in pregnancy labor, the puerperium and chorionic caner, using gas-liquid chromatography]. PMID- 4303635 TI - [Significance of pelvic angiography for the diagnosis of chorionic cancer]. PMID- 4303636 TI - [Spontaneous tumorigenesis in thymectomized mice (BALB-cf-R3-Se substrain)]. PMID- 4303637 TI - [Effect of dexamethasone on ventricular fluid pressure in cases of intracranial hypertension]. PMID- 4303638 TI - [Gastric motility and pH during natural human sleep]. PMID- 4303639 TI - [Clinico-laboratory study of adenoivrus infections arising in children with tuberculosis]. PMID- 4303640 TI - [Bacteriostatic activity of preparations of the 2d series and criteria of the resistance to them]. PMID- 4303641 TI - [Intravenous chemo-hormonotherapy in experimental tuberculosis and its effect on some biological properties of the disease-producing agent]. PMID- 4303642 TI - [Poliomyelitis vaccination, Sabin type, in 1-month-old and 3-month-old infants]. PMID- 4303644 TI - [Auto-interference of viruses isolated in infectious hepatitis]. PMID- 4303643 TI - [Mixed mesodermal tumor of the uterus]. PMID- 4303645 TI - [Metastatic alveolar carcinosis with differentiation of ciliary cells in extrapulmonary primary tumors. A contribution to the clinical cases of the so called alveolar cell carcinomas]. PMID- 4303646 TI - [On the analysis of changes in the innervation of muscles during the development of spastic contractures and their treatment in children]. PMID- 4303647 TI - [Transmitter substance release from carotid body chemoreceptors]. PMID- 4303648 TI - Amino acid fortification and the protein problem. PMID- 4303649 TI - Pseudomonas aeruginosa keratitis: mixed infections of the eye. PMID- 4303650 TI - Photochemistry of antibiotics. I. Oxidative coupling of o-aminophenol by photoirradiation. PMID- 4303651 TI - [Nonfilarial palpebral elephantiasis suspected to be angiofibroma: report of a case with autopsy findings]. PMID- 4303653 TI - Glycolipids from rat kidney. PMID- 4303652 TI - [Prognostic and therapeutic assessment of ovarian cancer on the basis of the enzyme status]. PMID- 4303654 TI - Studies on chemically modified cytochrome c. I. The acetylated cytochrome c. PMID- 4303655 TI - Specificity of phenotypic adaptation of Bacillus cereus to tetracycline. PMID- 4303656 TI - Chemically mediated transmission at a giant fiber synapse in the central nervous system of a vertebrate. AB - The hatchetfish, Gasteropelecus, possesses large pectoral fin adductor muscles whose simultaneous contraction enables the fish to dart upwards at the approach of a predator. These muscles can be excited by either Mauthner fiber. In the medulla, each Mauthner fiber forms axo-axonic synapses on four "giant fibers," two on each side of the midline. Each pair of giant fibers innervates ipsilateral motoneurons controlling the pectoral fin adductor muscles. Mauthner fibers and giant fibers can be penetrated simultaneously by microelectrodes close to the synapses between them. Electrophysiological evidence indicates that transmission from Mauthner to giant fiber is chemically mediated. Under some conditions miniature postsynaptic potentials (PSP's) are observed, suggesting quantal release of transmitter. However, relatively high frequency stimulation reduces PSP amplitude below that of the miniature potentials, but causes no complete failures of PSP's. Thus quantum size is reduced or postsynaptic membrane is desensitized. Ramp currents in Mauthner fibers that rise too slowly to initiate spikes can evoke responses in giant fibers that appear to be asynchronous PSP's. Probably both spikes and ramp currents act on the same secretory mechanism. A single Mauthner fiber spike is followed by prolonged depression of transmission; also PSP amplitude is little affected by current pulses that markedly alter presynaptic spike height. These findings suggest that even a small spike releases most of an immediately available store of transmitter. If so, the probability of release by a single spike is high for any quantum of transmitter within this store. PMID- 4303657 TI - A rectifying electrotonic synapse in the central nervous system of a vertebrate. AB - The adductor muscles of the pectoral fins of the hatchetfish Gasteropelecus are innervated by bilateral pools of about 40 motoneurons which lie primarily in the first spinal segment. A pair of giant fibers on each side of the medulla send processes ventroposteriorly to the motoneuron pools. Electrophysiological evidence indicates that giant fibers are presynaptic to ipsilateral motoneurons, but not to contralateral ones. Transmission across the giant fiber, motoneuron synapse is electrically mediated as is indicated by direct measurement of electrotonic spread in either direction across the synapse, and by the extremely short latency of the giant fiber postsynaptic potentials (PSP's) in the motoneuron. The coupling resistance across the synapse was calculated from measurements of input and transfer resistance. The coupling resistance rectifies in such a way as to facilitate spread of depolarization from giant fiber to motoneuron, and to oppose transmission in the opposite direction. As a consequence of rectification, the giant fiber PSP in a motoneuron is augmented by hyperpolarization of the motoneuron. The coupling resistance calculated on the basis of this effect is in good agreement with calculations from input and transfer resistance data. Rectification at the electrotonic synapses may permit the motoneurons to act in small swimming movements as well as to fire synchronously in an extremely fast escape reflex mediated by Mauthner and giant fibers. PMID- 4303658 TI - [Hereditary radicular neuropathy with sensory loss: study of a French-Canadian family]. PMID- 4303659 TI - [Frequency and significance of clinical and patho-anatomical diagnosis of acute renal failure in 1,000 deceased and autopsied patients]. PMID- 4303660 TI - Distortions of normal bone cell metabolism induced in multiple myeloma. PMID- 4303661 TI - Estradiol production after ovariectomy for carcinoma of the breast. PMID- 4303662 TI - Goodbye to the menopausal ovary. PMID- 4303663 TI - [Effect of vitamin C on the leukocytogram in chronic furfurol poisoning]. PMID- 4303664 TI - [On the problem of epithelial neoplasms of liver in children]. PMID- 4303665 TI - Thyroid-stimulating hormone and prostaglandin E1 stimulation of cyclic 3',5' adenosine monophosphate in thyroid slices. AB - Thyroid-stimulating hormone increased the cyclic 3',5'-adenosine monophosphate concentration in dog thyroid slices during a 1-minute incubation period and produced a maximum effect soon thereafter. The elevation persisted for at least 30 minutes. The concentrations of the cyclic 3',5'-adenosine monophosphate increased as the TSH concentration was increased from 0.125 to 50 milliunits per milliliter. Prostaglandin E(1), which increases glucose oxidation in dog thyroid slices, also increased the concentration of cyclic 3',5'-adenosine monophosphate. Although sodium fluoride stimulates thyroid adenyl cyclase, it did not increase concentration of cyclic 3',5'-adenosine monophosphate. Carbamylcholine and menadiol sodium diphosphate augment glucose oxidation in dog thyroid slices but do not change concentrations of cyclic 3',5'-adenosine monophosphate. PMID- 4303666 TI - [On the fluorescence of the chick embryo liver tissue in the visible region of the spectrum]. PMID- 4303667 TI - [Modern aspects of shock treatment]. PMID- 4303668 TI - [Presenting symptom ptosis--purposeful differential diagnostic procedure]. PMID- 4303669 TI - [Osteometry of the age changes in the pelvic bones and the whole pelvis in the cow]. PMID- 4303670 TI - [2 case reports of mixed tumors of the salivary glands characterized by "double metastasis"]. PMID- 4303671 TI - Neutralization kinetics of poliovirus by specific antiserum during the course of immunization of rabbits. PMID- 4303672 TI - Microscopic skin lesions in cattle with foot-and-mouth disease. PMID- 4303673 TI - Thermostability of cytomegalovirus strains. PMID- 4303674 TI - The cellular site of virus replication in the intestine of chicks infected with an avian adenovirus. PMID- 4303675 TI - Rct-marker tests on isolates from WM3 and Sabin type 3 attenuated poliovirus vaccines. PMID- 4303676 TI - Detection of polioviruses in human cerebrospinal fluid. PMID- 4303677 TI - Decreased insulin growth dependence in transformed hamster cells. PMID- 4303678 TI - [On the mechanism of action of angiotensin, with special reference to possible interference with glycide and lipid metabolism]. PMID- 4303679 TI - [Hypocalcemic effect of ACTH in man]. PMID- 4303680 TI - [The urinary elimination of 17-hydroxycorticosteroids and 17-ketosteroids in some dynamico-idiopathic functional tests in simple obesity, hirsutism and ovarian polycystic disease]. PMID- 4303681 TI - Studies on the biochemistry and fine structure of silica shell formation in diatoms. IV. Fine structure of the apochlorotic diatom Nitzschia alba Lewin and Lewin. PMID- 4303682 TI - [Oxidation of reduced nicotinamide-adenine dinucleotide in Rhodospirillum rubrum. I. Characterization of a soluble NADH dehydrogenase]. PMID- 4303683 TI - [On the regulation of the NAD-NADH ratio in yeast cells in relation with the pre incubation]. PMID- 4303684 TI - Thermostimulation of conidiation and succinic oxidative metabolism of neurospora crassa. PMID- 4303685 TI - On the metabolism of a myo-inositol-mannoside in Saccharomyces cerevisiae. PMID- 4303686 TI - [Periodate reaction of various phenylethanolamines. 2. Report on glycol splitting reagents]. PMID- 4303687 TI - [Effect of Aerosil and "filling material R 972" on the flow properties of zinc oxide]. PMID- 4303688 TI - [Mechanism and quantitative course of sorption of cationic drugs on colloidal silicic acid. 18. Report on the effect of pharmaceutic aids in preparation of drugs]. PMID- 4303689 TI - [African horse-sickness (Pestis equorum)]. PMID- 4303690 TI - Post-vaccination reactions in donkeys vaccinated with African horse-sickness polyvalent vaccines. PMID- 4303691 TI - Excretion of fowl plague virus by immune and non-immune fowls. PMID- 4303692 TI - [Study of alkylating agents for the inactivation of foot-and-mouth disease virus and the preparation of a new inactivated vaccine]. PMID- 4303693 TI - Attenuation of foot-and-mouth disease virus type "O" by serial passages in goats. PMID- 4303694 TI - [The role of foot-and-mouth disease antibodies of sera in BHK 21 industrial cell cultures used for the production of vaccines]. PMID- 4303695 TI - Occurrence and survival of foot-and-mouth disease virus in external lesions and discharges of experimentally infected buffalo-calves. PMID- 4303696 TI - [Typing of foot-and-mouth disease virus. World Reference Laboratory for Foot-and Mouth Disease Virus, Pirbright (Great Britain). Cumulative quarterly report]. PMID- 4303697 TI - [Typing of the foot-and-mouth disease virus. Nong-Sarai (Thailand)]. PMID- 4303698 TI - [Recent findings on viral diseases of the herpes group]. PMID- 4303699 TI - [The cell system for the synthesis of peptide hormones]. PMID- 4303700 TI - [Influence of high frequency stimulation of afferent nerves on motor neuron excitability]. PMID- 4303701 TI - [Post-traumatic synovioma]. PMID- 4303702 TI - [Hypoglycemic tumors of the pancreas]. PMID- 4303703 TI - [Estrogens and sex hormones--combination preparations. 1]. PMID- 4303704 TI - [Paget's disease of breast]. PMID- 4303705 TI - [Control mechanisms of cell division in mammalian cells "in vitro"]. PMID- 4303706 TI - [Aspartate-transcarbamylase acitivity in some human malignant tumors]. PMID- 4303707 TI - [Hemagglutination-inhibiting antibodies for parainfluenza 3 (HA-l) virus in bovine sera]. PMID- 4303708 TI - [On the symptomatology of peripheral disorders of the facial nerve]. PMID- 4303709 TI - [The importance of cytology for lung surgery]. PMID- 4303710 TI - [Chromosomes and virus]. PMID- 4303711 TI - [Virulence of Clostridium perfringens D-the pathogene of sheep enterotexemia]. PMID- 4303712 TI - [Mulspilication of the vaccinal strain of foot-and mouth disease virus in the culture of various cells]. PMID- 4303713 TI - [Obtaining attenuated strains of virus hepatitis in ducklings]. PMID- 4303714 TI - [On the etiology of papillomatosis]. PMID- 4303715 TI - Excretion of individual unconjugated 17-oxosteroids by normal female subjects. PMID- 4303716 TI - [Adsorption of lipoproteins. Treatment of sera with absorbents. I]. PMID- 4303717 TI - [Adsorption of coliphages. Treatment of sera with absorbents. II]. PMID- 4303718 TI - [Observations on the therapeutic effect of hysterosalpinography in sterility]. PMID- 4303719 TI - [Colorimetric determination of glycerol after periodic oxidation. Application in the determination of glycerides]. PMID- 4303720 TI - [Mediastinal teratoma (on a basis of an observation on a tridermic teratoma)]. PMID- 4303721 TI - [Infantile aortic aneurysm caused by aortic localization of "cytomegalic disease". Contribution to the study of viral arteritis]. PMID- 4303722 TI - [Pathology of primary benign and malignant tumors of the thrachea, with special reference to salivary type cylindroma and cylindroma like neoplasms]. PMID- 4303724 TI - New types of respiratory deficient mutants in Saccharomyces cerevisiae. I. A segregational mutant with ineffective respiration. PMID- 4303723 TI - [Influence of the uterus on the development of experimental oovarian tumours]. PMID- 4303725 TI - Some biologic and metabolic properties of the 186th passage of mouse chrysoidin hepatoma. PMID- 4303726 TI - [Adipokinetic effect of beta 1-24-corticotropin in humans]. PMID- 4303727 TI - [Studies on the mechanism of photoreduction of pyridine nucleotide by chromatophores from Rhodospirillum rubrum]. PMID- 4303728 TI - [Oxydation of reduced nicotinamide-adenine nucleotide in Rhodospirillum rubrum. II. On a reversible temperature-dependent activation of apoNADH dehydrogenase]. PMID- 4303729 TI - [Enzymes of the electron-transport particles of Rhodospirillum rubrum: properties of NADH and succinate cytochrome c reductase]. PMID- 4303730 TI - [Percutaneous resorption of corticosteroids. II. Resorption of flucocinolone acetonide through normal rat skin and its influence]. PMID- 4303731 TI - [Sensitivity of pathogenie microorganisms to bread-spectrum-antibiotics of the chloramphenicol- and tetracycline group in vitro]. PMID- 4303732 TI - [Some mechanisms of degradation and stabilization of the reconstructed respiratory chain of mitochondria in connection with the investigation of the mechanism of its formation]. PMID- 4303733 TI - [Investigation of the specificity of glycosidases of an enzyme preparation from Clostridium perfrigens (type A)]. PMID- 4303734 TI - [The site of action of deoxyadenosine on the synthesis of nucleic acids in the cancer cells]. PMID- 4303735 TI - [Mechanism of inhibition of mitochondrial respiratory chain by zinc ions]. PMID- 4303736 TI - [Some characteristics of soluble polysaccharides from Candida tropicalis and Candida viswanathii]. PMID- 4303737 TI - [On enzymic cleavage of cerebrosides]. PMID- 4303738 TI - [Benign synovioma (pathomorphology and histogenesis)]. PMID- 4303739 TI - Rapid plasma cortisol method using micro-columns. PMID- 4303740 TI - [Relation of body height and body weight to calendar age and skeletal age]. PMID- 4303741 TI - [Statistical, anatomopathological and clinical findings in 20 years of tumor and pseudotumor pathology of the hand]. PMID- 4303742 TI - [The biochemical basis of pain]. PMID- 4303743 TI - [Poliomyelitis due to poliovirus 3, with fatal outcome in an infant vaccinated with Sabin vaccine]. PMID- 4303744 TI - [Oxidation of L-arabitol by a polyalcohol dehydrogenase from sheep seminal vesicles]. PMID- 4303745 TI - Preliminary characterization of the collagenolytic activity of rat bone. PMID- 4303746 TI - [Study of the role of alveolar macrophages in respiratory physiopathology. Contribution of recent experimental technics to the study of cytotoxic action of mineral particles (silica and carbon), or infectious (grippal virus)]. PMID- 4303747 TI - [Research on healthy carriers of Cl. perfringens with heat-resistant spores]. PMID- 4303748 TI - [Preparations of the 2d series in the complex treatment of middle-aged and elderly patients with pulmonary tuberculosis]. PMID- 4303749 TI - [On a case of peripheral paralysis of the facial nerve due to a contralateral temporal tumor]. PMID- 4303750 TI - [Treatment of hypsarrhthmic myoclonic encephalopathy in children with levoglutamine and ACTH in high doses]. PMID- 4303751 TI - [The effect of adrenalectomy on the giant cells of developing cortex of the adrenal gland in the rat]. PMID- 4303752 TI - [Observation of spin echo of Na23 nuclei in living cells]. PMID- 4303753 TI - [The mechanism of action of interferon on smallpox virus multiplication and cellular metabolism]. PMID- 4303754 TI - [The effect of interferon on the production of hemagglutinins in chick fibroblasts infected with smallpox virus]. PMID- 4303755 TI - [Morphogenesis of persistent infection by adenovirus types 2 and 3 in tissue culture FL]. PMID- 4303756 TI - [Pathogenicity of chicken sarcoma virus for amphibians and reptiles]. PMID- 4303757 TI - [Histochemical study of oxidation-reduction enzymes in the process of viral carcinogenesis]. PMID- 4303758 TI - [A study of viruses isolated from patients with Botkin's disease and persons who had contact with them]. PMID- 4303759 TI - [Mutagenic and inactivating effect of hydroxylamine in treating infectious RNA and native poliomyelitis virus]. PMID- 4303760 TI - [Sensitivity according to age of cultures of pig embryo kidney cells to foot and mouth disease virus]. PMID- 4303761 TI - [Results of the campaign against virus infections in the USSR over the past 50 years]. PMID- 4303762 TI - [Morphologic criteria of tumorogenicity of various cell cultures in heterotransplant experiments with hamsters]. PMID- 4303763 TI - [Chronic infection of cells by polyoma virus in vitro]. PMID- 4303764 TI - [The effect of poliovirus on the electrokinetic potentials of susceptible cells]. PMID- 4303765 TI - [Sensitivity of various virus--cell systems to preparations of human interferon]. PMID- 4303766 TI - [Viremia in adenovirus infections in newborns]. PMID- 4303767 TI - [Detection of latent adenoviruses in tonsil and adenoid tissues after ultraviolet irradiation]. PMID- 4303768 TI - [Chicken myeloblastosis virus in cell cultures. Myeloblastosis virus in chick fibroblast cultures]. PMID- 4303769 TI - [Entamoeba histolytica and man]. PMID- 4303770 TI - Neuroglia proliferation studies in tissue culture. PMID- 4303771 TI - The influence of age on infection in experimental Herpes simplex encephalo-myelo neuritis of mice as demonstrated by fluorescent antibody method. PMID- 4303772 TI - The effect of estrogen on intravenous glucose tolerance in woman. PMID- 4303773 TI - Effect of trace metals on placental metabolism. PMID- 4303774 TI - Palpable axillary lymph nodes in cancer of the breast. Structural and biologic considerations. PMID- 4303775 TI - Studies of Burkitt lymphoma cells. 3. Equilibrium density gradient centrigugation of virus particles isolated from Burkitt lymphoma cell lines. PMID- 4303776 TI - Preoperative irradiation of cancer of the lung. Preliminary report of a therapeutic trial. A collaborative study. PMID- 4303777 TI - Histologic effects of endolymphatic radiotherapy. PMID- 4303778 TI - Indirect thyroid lymphography in the dog using radio-iodinated lipiodol ultra fluid. PMID- 4303779 TI - Effects of necrotic tumor on hepatic cells in the rat. An ultrastructural study. PMID- 4303780 TI - Glomangioma. An ultrastructural study. PMID- 4303781 TI - Neoplasms of the nervous system in Thailand. PMID- 4303782 TI - [Roentgen picture of glomangiomas of the temporal bone]. PMID- 4303783 TI - Localization and characteristics of the cortical waves associated with eye movement in the cat. PMID- 4303784 TI - Macroelectrode responses with stimulation and recording within hippocampus and related structures during different states of consciousness. PMID- 4303785 TI - Induction of both emotional behavior and a novel form of REM sleep by chemical stimulation applied to cat mesencephalon. PMID- 4303786 TI - [Adrenal cortex and ovarian intervention in the pathogenesis of minor hyperandrogenism. I. Study of fractionated urinary 17-ketosteroids in basal and dynamic conditions in 30 women with hirsutism]. PMID- 4303787 TI - [Respiratory function studies in subjects with occupational exposure to pumice dust]. PMID- 4303788 TI - Hepatocellular carcinoma in a fowl. PMID- 4303789 TI - Some determinants of the effects of VAL-5-angiotensin II amide on glomerular filtration rate and sodium excretion in dogs. AB - In 12 dogs anesthetized with chloralose, angiotensin (angiotensin II amide) given intravenously increased the glomerular filtration rate (GFR) of an ischemic kidney while simultaneously having little effect on the GFR of the contralateral kidney. In the ischemic kidney, in 14 of 30 observations, increments of GFR greater than 100% of mean control GFR (9 ml/min) occurred in response to angiotensin. The magnitude of the increase in GFR produced by angiotensin was independent of dose (range 0.005-0.050 mug/kg per min), the degree of accompanying pressor response, and alterations in renal blood flow (RBF) (electromagnetic flow-meter). In the ischemic kidney, increments of GFR could be produced by sub-pressor doses of angiotensin. Dissociations between increments of GFR and sodium excretion occurred. Equivalent increments of GFR in the ischemic kidney in dogs receiving either 5% glucose in water or 10% mannitol in 0.3% saline were associated with natriuresis only in the latter group: a) as an initial response of the contralateral kidney to renal arterial constriction (RAC) in spite of a concomitant reduction in RBF and an unchanged GFR; b) in the ischemic kidney on giving angiotensin. The natriuresis produced by angiotensin was independent of the magnitude of elevations in blood pressure, altered filtration fraction, and was associated with a further reduction in RBF. After release of RAC in the dogs receiving mannitol, an antinatriuresis was again observed in response to angiotensin. The presence of unilateral renal ischemia allowed the demonstration of a differential action of angiotensin on the GFR of an ischemic and nonischemic kidney. The natriuresis in response to angiotensin requires, in addition to mannitol, the participation of undefined factors invoked by unilateral renal ischemia. PMID- 4303790 TI - Effect of mixed micellar lipid on the absorption of cholesterol and vitamin D3 into lymph. AB - The absorption of endogenous cholesterol, labeled with tracer doses of cholesterol (14)C or cholesterol-(3)H and of near physiological doses of vitamin D(3)-(3)H was studied in rats with cannulated intestinal lymphatics. The effects of administering mixed micellar solutions of fatty acid, monoglyceride, and bile salt on the absorption of these labeled sterols was determined. It was observed that the specific activity of free cholesterol and the amounts of vitamin D(3) appearing in lymph were significantly increased during the intraduodenal administration of mixed micellar solutions of either linoleic or palmitic acid, in contrast to control rats receiving a micellar solution of taurocholate. These increases were related linearly to the lymph triglyceride level. In addition it was observed that when the linoleic acid solution was administered there was a more marked increase in the ratio of the specific activities of free and esterified cholesterol in lymph than with either the palmitic acid or taurocholate solutions. Additional studies in rats with intact lymphatics showed that the uptake of labeled cholesterol and vitamin D(3) from the intestinal lumen into the wall was similar whether the sterols were administered in taurocholate or in mixed micellar solution. These findings suggest that mixed micellar lipid increased the rate of appearance of labeled free cholesterol and vitamin D(3) in lymph by enhancing their transport out of the intestinal mucosa, rather than by an effect on uptake. PMID- 4303791 TI - Activation of aldosterone secretion in primary aldosteronism. AB - Angiotensin infusion evokes marked increases in aldosterone secretion in primary aldosteronism and little change in secondary aldosteronism. The low plasma renin activity of primary aldosteronism and the elevated plasma renin activity of secondary aldosteronism are thought to account for this differential response. The effect of angiotensin on aldosterone and 18-hydroxycorticosterone secretion was studied during adrenal vein catheterization in seven patients with primary aldosteronism (whose plasma renin activity had been elevated following spironolactone therapy), one hypertensive patient with normal plasma renin activity and normal aldosterone secretion, two patients with secondary aldosteronism who had elevated plasma renin activity, and one anephric patient whose plasma renin activity was 0. Adrenal venous aldosterone and 18 hydroxycorticosterone were measured before and after a ten min sub-pressor angiotensin infusion. The cells of the aldosterone-producing adenoma (APA) respond to small increases in plasma angiotensin with large increases in secretion of aldosterone and 18-hydroxycorticosterone. The dose of angiotensin capable of evoking this response from the aldosterone-producing adenoma produces little or no change in the secretion of the steroids from nontumorous glands. The augmentation of aldosterone secretion, induced by angiotensin, in primary aldosteronism is due solely to increased secretion by the adenoma and not by the contralateral zona glomerulosa. The increased sensitivity of the aldosterone producing adenoma is characteristic of the tumor. This response is independent of fluctuations in endogenous plasma renin activity. This sensitivity is not blunted by high plasma renin activity, nor is it a function of tumor mass for the effect is observed in aldosterone-producing adenomas regardless of size. ACTH injection after angiotensin infusion resulted in a marked increase in aldosterone concentration in the effluent from the nontumorous adrenal, but was not capable of producing further increases in aldosterone concentration in the effluent from the APA. In view of this exquisite sensitivity to infused angiotensin, it may be that the small variations in endogenous plasma renin activity that have been observed in primary aldosteronism may be capable of evoking large changes in aldosterone secretion in patients with aldosterone-producing adenomas. PMID- 4303792 TI - Cytophotometric quantitation of glucose 6-phosphatase activity in rat liver. PMID- 4303793 TI - Correlation between the neutralizing activity of human serum against Herpes simplex virus and a simian herpesvirus (SA8). PMID- 4303794 TI - A system of tissue cultures for the study of a mouse leukemia virus. PMID- 4303795 TI - Effect of intranasal reovirus infection on antibacterial activity of mouse lung. PMID- 4303796 TI - Spread of enteric live adenovirus type 4 vaccine in married couples. PMID- 4303797 TI - Studies of a newly recognized poxvirus of monkeys. PMID- 4303798 TI - The fibre size and content of the radial and sural nerves. PMID- 4303799 TI - Primitive reflex activity in primary and symptomatic Parkinsonism. PMID- 4303800 TI - Thalidomide neuropathy: a clinical electrophysiological, and histological follow up study. PMID- 4303801 TI - Globular neuropathy. A disorder of axons and Schwann cells. PMID- 4303802 TI - Histochemistry of Rathke pouch tumours. PMID- 4303803 TI - Gas-liquid chromatographic analysis of sural nerves in peripheral neuropathies. PMID- 4303804 TI - Cytochemistry of sea urchin gametes. I. Intramitochondrial localization of glycogen, glucose-6-phosphatase, and adenosine triphosphatase activity in spermatozoa of Paracentrotus lividus. PMID- 4303805 TI - [The dynamics of arterial pressure and the level of 17-hydroxycorticosteroids in the blood and urine in patients with hypertension during loading with ACTH]. PMID- 4303806 TI - [The role of pyridoxine in the pathogenesis and therapy of the spastic hypsarrhythmia syndrome. Studies and considerations on 56 cases]. PMID- 4303807 TI - Effect of BCG and allogeneic tumor cells on adenovirus type 12 tumorigenesis in mice. PMID- 4303808 TI - Relationship between virion incidence and pathological stage in virus-induced leukaemia. PMID- 4303809 TI - Nuclear sheets in epithelial and connective tissue cells. PMID- 4303810 TI - Inhibition of gastric acid secretion in vitro by prostaglandin E1. PMID- 4303811 TI - Nerve involvement in leprosy. Pathogenesis and significance. PMID- 4303812 TI - Central effect of the secondary endings of muscle stretch receptors in man. PMID- 4303813 TI - Neurological diagnosis of ruptured cervical discs. PMID- 4303814 TI - Femoral neuropathy with abdominal pain. PMID- 4303815 TI - Venesection therapy in idiopathic haemochromatosis. An analysis of 40 treated and 18 untreated patients. PMID- 4303816 TI - Poliovirus crystals within the endoplasmic reticulum of endothelial and mononuclear cells in the monkey spinal cord. AB - The lumbar motor columns of a cynomolgus monkey that had become tetraplegic after experimental infection with a highly virulent strain of type 3 poliovirus were examined by electron microscopy. Crystalline aggregates of poliovirus occurred within the endoplasmic reticulum of endothelial cells as well as of mononuclear inflammatory cells. This finding suggests that the endoplasmic reticulum might be much more involved in poliovirus multiplication than has been previously supposed. PMID- 4303817 TI - Incidence of thrombosis in portal venous stasis and hypertension. PMID- 4303818 TI - Sporotrichosis and nocardiosis in a patient with Boeck's sarcoid. PMID- 4303819 TI - [Studies on the effect of angiotensin II on blood circulation in normal pregnancy]. PMID- 4303820 TI - [Pulmonary hypertension and glomangiomatosis of the lungs]. PMID- 4303821 TI - Fetal hamartoma of kidney. A benign, symptomatic, congenital tumor, not a form of Wilms' tumor. PMID- 4303822 TI - Susceptibility of Bordetella pertussis to nine antimicrobial agents. PMID- 4303823 TI - Antiviral effectiveness of chlorine bleach in household laundry use. PMID- 4303824 TI - The enzymic conversions of 13-hydroperoxy-cis-9-trans-11-octadecadienoic acid into 13-hydroxy-12-oxo-cis-9-octadecenoic acid. PMID- 4303825 TI - Anthelmintics, new and old. PMID- 4303826 TI - Differentiation of pseudoinflammatory colloid carcinoma from colitis cystica profunda. PMID- 4303827 TI - [4 cases of synovial tumors arising in the tendon sheaths]. PMID- 4303828 TI - Investigation of human malignant tumors in India for simian virus 40 etiology. PMID- 4303829 TI - Multiplication of avian leukosis virus in endocrine organs of congenitally infected chickens. PMID- 4303830 TI - Etiology of Burkitt's lymphoma--an alternative hypothesis to a vectored virus. PMID- 4303831 TI - A search for avian leukosis virus and antiviral activity in the blood of leukemic and nonleukemic adults and children. PMID- 4303832 TI - Energy expenditure and nitrogen metabolism of rats bearing a transplantable anterior pituitary tumor. PMID- 4303833 TI - Ultrastructure of Wilms' tumor. I. Epithelial cell. PMID- 4303834 TI - Subacute "poliomyelitis" and Hodgkin's disease. PMID- 4303835 TI - The neurological complications of ankylosing spondylitis. PMID- 4303836 TI - Conductance changes during pyramidally induced postsynaptic potentials in red nucleus neurons. PMID- 4303837 TI - Slow inhibitory and excitatory postsynaptic responses in single cells of mammalian sympathetic ganglia. PMID- 4303838 TI - Comparative study of acetylcholine and 5-hydroxytryptamine receptors on single snail neurons. PMID- 4303839 TI - Radioisotopes in malignancies in children. Use in the study of involvement by primary and metastatic processes in brain and liver. PMID- 4303840 TI - Glomus jugulare tumor. PMID- 4303841 TI - Glomus jugulare tumor. PMID- 4303842 TI - [Recent progress in the study of synthetic ACTH. Its clinical application]. PMID- 4303843 TI - The recorded body-sway response to galvanic stimulation of the labyrinth: a preliminary study. PMID- 4303844 TI - [Canditoxin, a new toxic substance isolated from Candida albicans. 5. Enzymic activity, with special reference to phosphatase]. PMID- 4303845 TI - Changes in surface antigens of SV40-virus transformed cells. PMID- 4303846 TI - The effect of exogenous dopamine on ACTH secretion. PMID- 4303847 TI - Adrenal cortical control of adrenal medullary function. PMID- 4303848 TI - Skin test potency in guinea pigs of Entamoeba histolytica antigen (histolyticin) prepared from axenically cultivated amebas. PMID- 4303849 TI - Adrenergic receptor blockers on pressor activity of incubated human plasma. PMID- 4303850 TI - Effect of cycloheximide on the antiviral action of interferon. PMID- 4303851 TI - Viral inhibition of the phytohemagglutinin response of human lymphocytes and application to viral hepatitis. PMID- 4303852 TI - Immunology of mouse mammary tumor virus. PMID- 4303853 TI - Giant fibroadenoma (benign cystosarcoma phylloides): report of case in 13-year old girl. PMID- 4303854 TI - Portal diversion in glycogen storage disease. PMID- 4303855 TI - [Does there exist a painful, autonomous, peripheral maxillary facial syndrome?]. PMID- 4303856 TI - The effects of vasoactive drugs on reticuloendothelial function in experimental shock and combined injury. PMID- 4303857 TI - [Pulmonary adenomatosis in newborn infants]. PMID- 4303858 TI - [Antimicrobial effect of potential isothiocyanate producers. 3]. PMID- 4303859 TI - [Tritium incorporation in ascitic tumor cells during incubation with glycerin-2-T and its modification by D- and L-glycerinaldehyde]. PMID- 4303860 TI - [Differential diagnosis of lung infarction, demonstrated on surgical patients]. PMID- 4303861 TI - Ethambytol in the retreatment of pulmonary tuberculosis. United States Public Health Service cooperative trial. PMID- 4303862 TI - [Treatment of drug resistant chronic pulmonary tuberculosis with a number of tuberculostatics]. PMID- 4303863 TI - The treatment of drug resistant chronic pulmonary tuberculosis with new tuberculostatics. PMID- 4303864 TI - The clostridial flora of marine sediments from a productive and from a non productive area. PMID- 4303866 TI - An immunologic comparison of five murine leukemia viruses grown in tissue culture. PMID- 4303865 TI - Serological characterization of gamma-M(19 S) and gamma-G(7 S) rabbit antibiodies in response to Entamoeba histolytica antigens. PMID- 4303867 TI - Quantitative immunochemical determination of the isozymes of aspartate aminotransferase in rat livers and transplantable rat hepatomas. PMID- 4303869 TI - Ultrastructure of chick embryo cells altered by strain MC29 avian leukosis virus. PMID- 4303868 TI - Changes in virus attachment and other surface properties of L4946 mouse leukemia cells on adaptation of growth in tissue culture. PMID- 4303870 TI - The effect of mumps virus on the resistance of Burkitt lymphoma cell lines to various viruses. PMID- 4303871 TI - Effect of herpes simplex virus on cultured Burkitt tumor cells and its failure to influence the Epstein-Barr virus carrier state. PMID- 4303872 TI - [Proceedings of the conference on the recent studies on tumors of probable viral origin, with special reference to African lymphoma. June 5-6, 1965. Introduction to the problem]. PMID- 4303873 TI - Deep spreading carcinoma of the stomach causing death within seven months of last normal x-ray examination. PMID- 4303874 TI - Fine structure of the pars distalis and interrenals of Taricha torosa after administration of metopirone (SU-4885). PMID- 4303875 TI - Physiological evidence for a pituitary-adrenocortical feedback mechanism in the eel (Anguilla rostrata). PMID- 4303876 TI - Interconversions of estrogens and related developmental effects in sand dollar eggs. PMID- 4303877 TI - Poliovirus antibody response in serum and nasal secretions following intranasal inoculation with inactivated poliovaccine. PMID- 4303878 TI - Preparation of rabbit immune serum with neutralizing activity against a simian cytomegalovirus (SA6). PMID- 4303879 TI - Immune response of cattle to different serotype antigens in monovalent and trivalent foot-and-mouth disease vaccines. PMID- 4303880 TI - Mammary tumor virus potentiation of endogenous prolactin effect on mammary gland differentiation. PMID- 4303881 TI - Demonstration of tumor-specific immunity against antigens unrelated to the mammary tumor virus in spontaneous mammary adenocarcinomas. PMID- 4303882 TI - Response of hyperplastic alveolar nodule outgrowth-line D1 to mammary tumor virus, nodule-inducing virus, and prolonged hormonal stimulation acting singly and in combination. PMID- 4303883 TI - Acquired immunological tolerance and carcinogenesis by the mammary tumor virus. I. Influence of neonatal infection with the mammary tumor virus on the growth of spontaneous mammary adenocarcinomas. PMID- 4303884 TI - Acquired immunological tolerance and carcinogenesis by the mammary tumor virus. II. Immune responses influencing growth of spontaneous mammary adenocarcinomas. PMID- 4303885 TI - Nephroblastoma (Wilms tumor) and congenital aniridia. PMID- 4303886 TI - Spinal cord representation of the peripheral neural pathways of the micturition reflex. PMID- 4303887 TI - The action of staphylococcal alpha toxin and the venom from Bitis gabonica on rat stomach strip. PMID- 4303888 TI - [Hidradenoma of the ceruminous glands of the external auditory canal]. PMID- 4303889 TI - [Mixed tumor of the trachea]. PMID- 4303890 TI - [Unusual causes of neonatal jaundice]. PMID- 4303891 TI - [Clinico-radiological characteristics of adenoviral disease and influenza in early childhood]. PMID- 4303892 TI - [Diagnosis of mixed acute respiratory viral infections in young children]. PMID- 4303893 TI - [Clinical significance of the determination of phosphatase activity in the neutrophils of the blood]. PMID- 4303894 TI - [Paget's carcinoma of the mammary gland (morphology, clinical picture, therapy)]. PMID- 4303895 TI - [Study of some current viral encephalitides in the Socialist Republic of Rumania]. PMID- 4303896 TI - [Liver diseases in amoeba infections]. PMID- 4303897 TI - [On the growth and increase of eye tumors]. PMID- 4303898 TI - Electron microscopic study of isolated Kupffer cells. PMID- 4303899 TI - Analysis of excitation process in squid giant axons under bi-ionic conditions. PMID- 4303900 TI - Inactivation of angiotensin in shock. PMID- 4303901 TI - Plasma renin activity in hypertensive rats after treatment with renin preinhibitor. PMID- 4303902 TI - Influence of glycolysis on NADH content in human erythrocytes. PMID- 4303903 TI - Effects of gallamine and physostigmine on transmission through the cuneate nucleus. PMID- 4303904 TI - Renal extraction of PAH, GFR, and UNaV in the rat during infusion of angiotensin. PMID- 4303905 TI - Antagonism of angiotensin by hydralazine on renal blood flow and erythropoietin production. PMID- 4303906 TI - Caffeine effects on transmitter depletion and mobilization at motor nerve terminals. PMID- 4303907 TI - Influence of cycling, pregnancy, labor, and suckling on corticosterone-ACTH levels. PMID- 4303908 TI - Hyperbaria in experimental bile peritonitis. PMID- 4303909 TI - Spontaneous mammary adenocarcinoma in mice: influence of thymectomy and reconstitution with thymus grafts or spleen cells. PMID- 4303910 TI - Regulatory properties of a plant NAD: isocitrate dehydrogenase. The effect of inorganic ions. PMID- 4303911 TI - Malate dehydrogenases of ox kidney. 2. Two substrate kinetic and inhibition analyses. PMID- 4303912 TI - The reversible removal of one specific copper(II) from fungal laccase. PMID- 4303913 TI - The substrate specificity of pigeon liver NAD kinase. PMID- 4303914 TI - [On the possible use of inhalation of potassium carbonate for the prevention of pneumoconiosis]. PMID- 4303915 TI - The oxidation of exogenous and endogenous cytochromeC in mitochondria. A biochemical and ultrastructural study. AB - The effect of the nonionic detergent Lubrol on the oxidation of endogenous and exogenous cytochrome c by cytochrome oxidase in intact and fragmented mitochondria was studied. Mitochondria and mitochondrial fragments from liver, kidney, heart, and skeletal muscle have been used. Negatively stained preparations of intact mitochondria showed the particles of Fernandez-Moran on the matrix side of their inner membrane system: under these conditions, the oxidation rate of externally added cytochrome c was very high, and it was stimulated very poorly by Lubrol. Mechanical fragmentation of liver mitochondria yielded vesicles with a smooth external profile: also under these conditions, the oxidation of externally added cytochrome c was very high, and poorly stimulated by Lubrol. The oxidation of endogenous cytochrome c was also unaffected by Lubrol. On the other hand, fragmentation of heart and skeletal muscle mitochondria yielded vesicles having numerous particles of Fernandez-Moran on their external profiles. Under these conditions, the oxidation of exogenous cytochrome c was low and was markedly stimulated by Lubrol. On the contrary, no activation of the oxidation of endogenous cytochrome c was induced by the detergent. The results indicate a difference in the permeability properties of the two faces of the inner mitochondrial membrane: a permeability barrier for cytochrome c is suggested to exist at the inner face. PMID- 4303916 TI - The effect of temperature on ATP levels in cells of an ascitic hepatoma. PMID- 4303918 TI - Glomangioma of external ear. PMID- 4303917 TI - Studies on the inhibitory properties of sodium thioglycollate on the germination of wet spores of clostridia. PMID- 4303919 TI - The effect of local blockage of motor nerve terminals. AB - 1. Electrophoretic application of tetrodotoxin (TTX) was used to study the effect of localized blockage of impulses in motor nerve terminals.2. Under suitable conditions it can be shown that local production of end-plate potentials ceases distal to the site of TTX application, while it continues without diminution at proximal sites of the same terminal arborization.3. It is concluded that electrotonic spread of an action potential wave along a motor nerve terminal is insufficient to elicit transmitter release. Active propagation in the terminals is an essential requirement for neuromuscular transmission. PMID- 4303920 TI - The re-distribution of cytochrome oxidase, noradrenaline and adenosine triphosphate in adrenergic nerves constricted at two points. AB - 1. The experiments correlate certain changes in the ultrastructure of cat hypogastric nerves constricted at two points with the distribution of a mitochondrial enzyme (cytochrome oxidase), noradrenaline (stored in some of the vesicles with an electron dense core, i.e. granular vesicles) and adenosine triphosphate (ATP) (present in noradrenaline storage granules, mitochondria and the soluble fraction of the axon).2. Noradrenaline (NA) and granular vesicles accumulated proximal but not distal to both constrictions. The total amount of NA and the concentration of granular vesicles above the first constriction was greater than that present in a similar piece of normal nerve, indicating that the cell body was continuing to produce the transmitter despite injury to its axon. The granular vesicles proximal to the first constriction were found in swollen or distorted axons and in new axonal outgrowths. It was concluded that the movement of NA in these constricted nerves was only centrifugal in direction.3. Mitochondria and cytochrome oxidase accumulated on both sides of the two constrictions, indicating a bi-directional movement of mitochondria in the damaged axons. The possibility that some of the increase in the cytochrome oxidase could be related to an increase in the number of mitochondria in cells other than neurones is considered.4. The adenosine triphosphate content increased on both sides of the two constrictions. This increase developed more slowly and was less marked than that of the other two substances.5. It was concluded that (a) there was a close correlation between the behaviour of noradrenaline and granular vesicles and between cytochrome oxidase and mitochondria, (b) the dense cored vesicles and the mitochondria moved independently of one another and at different rates after constriction of non-myelinated axons, (c) while some of the changes may be attributed to an obstruction to the free movement of axoplasm others may be due to an active reaction to axonal injury, and (d) localized intraaxonal synthesis of noradrenaline and cytochrome oxidase did not occur between the two constrictions. PMID- 4303921 TI - Adrenal secretion rates and adrenal tissue concentrations of pregnenolone, progesterone, 11 beta OH-androstenedione and some other steroids in young pigs and dogs. AB - 1. The rates were measured at which a number of different steroids were secreted by the adrenal gland of the eviscerated and nephrectomized young pig and dog.2. In addition to cortisol and corticosterone the following steroids were consistently found to be present in the adrenal venous blood: pregnenolone, progesterone, 11betaOH-progesterone, androstenedione, 11betaOH-androstenedione and adrenosterone.3. The sum of the latter steroids could amount to as much as 30% of the total steroid secretion.4. A severe deficit in the blood volume increased the secretion of pregnenolone and the 17-oxo steroids in the pig.5. alpha-ethyltryptamine failed to inhibit ACTH release if the animals were eviscerated and nephrectomized, or if they were anaesthetized with chloralose instead of pentobarbitone sodium.6. The same steroids as in the adrenal venous blood were found in extracts from the adrenal glands of a number of species.7. The amount of individual steroids present in the adrenal gland of the stressed pig and dog was compared with the rate at which each had been secreted immediately before the excision of the gland.8. There was a positive correlation between the adrenal concentrations and the secretion rates of cortisol, the major glucocorticoid secreted by the pig and the dog.9. In contrast, the rate at which pregnenolone was secreted did not show a consistent relationship to its concentration in the gland.10. A storage mechanism for pregnenolone in the adrenal cortex is proposed. PMID- 4303923 TI - Colostomy and its management. PMID- 4303922 TI - Urinary excretion of polymyxin B sulfate and sodium colistimethate in dogs. PMID- 4303924 TI - The effects of fever on sleep and dream patterns. PMID- 4303925 TI - Angiographic findings in 16 patients with juvenile nasopharyngeal angiofibroma. PMID- 4303926 TI - Angiographic features of cavernous hemangioma of liver. PMID- 4303927 TI - A new method for radiographic visualization of the bronchopulmonary lymphatic system. PMID- 4303928 TI - [Preservation of erythrocytes by freezing in the presence of glycerol and sorbitol. II. Dosage of glycerol and sorbitol in the blood. Behavior of these polyalcohols at contact with the erythrocytes]. PMID- 4303929 TI - [On recognition of lung chemodectomas]. PMID- 4303930 TI - [Elevated protein synthesis in liver puncture specimen of patients with acute hepatitis]. PMID- 4303931 TI - [Demyelinizing organophosphor compounds and lipogenesis of peripheral nerves]. PMID- 4303932 TI - [Considerations on the genesis of so-called medulloblastoma]. PMID- 4303933 TI - Rhinovirus infections in an industrial population. IV. Infections within families of employees during two fall peaks of respiratory illness. PMID- 4303934 TI - Salt-losers and non salt-losers in congenital adrenal hyperplasia. PMID- 4303935 TI - [The prevention of food poisoning in communal environments]. PMID- 4303936 TI - Glycerylphosphorylcholine diesterase: effects of dietary choline deficiency. PMID- 4303937 TI - Simple method for isolation of crude mono- and digalactosyl diglycerides from wheat flour. PMID- 4303939 TI - Immunization of day-old chicks against fowl pox. PMID- 4303938 TI - Metabolic effects of imidazole in adipose tissue. PMID- 4303940 TI - [Interactions of silicogenic dusts and lysosomes]. PMID- 4303941 TI - Action of strychnine on the specific somatosensory projection pathway. PMID- 4303942 TI - Some pharmacological effects of halothane in fowls. PMID- 4303943 TI - Thin-layer chromatography of carbohydrates on silica gel impregnated with sodium acetate, monosodium phosphate and disodium phosphate. PMID- 4303944 TI - [The relationship between chemical structure and chromatographic behavior of cardiac glycosides. VI. Problems arising in thin-layer chromatographic structure analysis using silica gel as adsorbent]. PMID- 4303945 TI - The role of elution solvent in quenching of Ittrich estrogen fluorescence reaction observed with silica gel eluates. PMID- 4303946 TI - Separation of mental-EDTA complexes by thin-layer chromatography. PMID- 4303947 TI - A longitudinal study of the urinary excretion of individual steroids in children from 8 to 12 years old. PMID- 4303948 TI - The regulation of aldosterone production in normal and sodium-deficient rats. PMID- 4303949 TI - A simple method for the separate estimation of 11-deoxy and 11-oxygenated 17 hydroxycortico-steroids in human urine. PMID- 4303950 TI - Failure of stilboestrol to stimulate corticosteroid excretion in hypophysectomized guinea-pigs. PMID- 4303951 TI - Vaccination with live type 4 adenovirus: evaluation of antibody response and protective efficacy. PMID- 4303952 TI - Genetic marker studies on poliovirus type 1 strains from the Blackburn poliomyelitis outbreak in 1965. PMID- 4303953 TI - Sero-epidemiological study of reovirus infection amongst the normal population of the Chandigarh area--northern India. PMID- 4303954 TI - Bacteriological aspects of air-conditioning plants. PMID- 4303955 TI - The persistence of foot-and mouth disease virus in sheep. PMID- 4303956 TI - Relationship of electrical activity in pontine reticular formation and lateral geniculate body to rapid eye movements. PMID- 4303957 TI - Experiences in laboratory diagnosis of adenovirus infections in routine medical practice. PMID- 4303958 TI - [Some regulations of growth and oxygen consumption by Candida cultures on different substrates]. PMID- 4303959 TI - [Sigmund Freud and the dream research of today]. PMID- 4303960 TI - Studies on the toxicity of chloroform on the isolated rabbit heart under different conditions of coronary circulation. PMID- 4303961 TI - Changes in distal sodium reabsorption during angiotensin infusion in response to furosemide. PMID- 4303962 TI - [Current views of masculinizing tumors of the ovary]. PMID- 4303963 TI - [The clinical picture of intestinal schistosomiasis]. PMID- 4303964 TI - [Combined hormone therapy of patients with diffuse forms of alopecia]. PMID- 4303965 TI - [Mixed tumor of the middle ear with malignant course]. PMID- 4303966 TI - Transmission of mouse leukemia by oral route. PMID- 4303967 TI - [Eye movements during sleep (preliminary note)]. PMID- 4303968 TI - Enzymatic changes in asphyxia, experimental pulmonary edema, and drowning. PMID- 4303969 TI - Rhabdomyosarcohepatoma in an adult and embryonal hepatoma in a child. PMID- 4303970 TI - Gas-liquid chromatographic studies of urinary 17-ketosteroids in three patients with adrenocorticotropin-producing bronchogenic carcinoma. PMID- 4303971 TI - Asymptomatic solitary pulmonary nodule. A study of resected cases. PMID- 4303972 TI - [Central scotomas in sellar and suprasellar tumors]. PMID- 4303973 TI - The rat as experimental model in sequential radiologic study of the thoracic duct. PMID- 4303974 TI - [Hereditary craniofacial dysostosis and syndactylia. A contribution to the study of relations between Apert's disease and Crouzon's disease]. PMID- 4303975 TI - Pathogenesis of hypoglycemia in hamsters with a transplantable islet-cell tumor. PMID- 4303976 TI - [Effect of angiotensin on coronary circulation]. PMID- 4303977 TI - [Research on the pathogenesis of poliomyelitis. Proposed new scheme]. PMID- 4303978 TI - [Oto-neurosurgical collaboration in the total ablation of a tympano-jugular glomus tumor with intracranial extension]. PMID- 4303980 TI - [Some problems of corticosteroid metabolism in patients with pulmonary tuberculosis]. PMID- 4303979 TI - [Purification and characterization of red cell angiotensinase]. PMID- 4303981 TI - [On the effect of anabolic steroids on normal and denervated muscle]. PMID- 4303982 TI - [Hypophyseo-adrenal hormones in the treatment of tuberculosis]. PMID- 4303983 TI - [Complement-fixing antibody in mammals with Rous sarcoma]. PMID- 4303984 TI - [A study of the effect of herpes simplex virus on human diploid cells (strin HLDC 4)]. PMID- 4303985 TI - [A study of the infectious and transforming activity of Rous virus in various tissue cultures]. PMID- 4303986 TI - [A study concerning the detection and typing of foot and mouth disease virus by means of the fluorescent antibody technic]. PMID- 4303987 TI - [On serologic reactions to myxoviruses in parotitis in humans]. PMID- 4303988 TI - [Production of herpes simplex mutants resistant to dextran sulfate]. PMID- 4303989 TI - [Detection of an intracranial arteriovenous fistula in a tympano-jugular glomus tumor]. PMID- 4303990 TI - [Action of Bordetella pertussis on the lymphatic tissue of mice. I. Increase in the spleen weight of white mice following injection of Bordetella pertussis]. PMID- 4303991 TI - Studies on the role of adenylcyclase in insulin secretion. PMID- 4303992 TI - Role of free fatty acids in glucose homeostasis. PMID- 4303993 TI - Hepatoblastoma and hepatoma in infancy and childhood. Light and electron microscopic studies. PMID- 4303994 TI - Femoral compression neuropathy in hemorrhagic disorders. PMID- 4303995 TI - [Human interferons induced in vitro by synthetic polynucleotides]. PMID- 4303996 TI - The use of guanidine thiocyanate to fractionate DNA-like RNA adsorbed on methylated bovine albumin-kieselguhr columns. PMID- 4303997 TI - Some properties of ribonucleoprotein particles in the isolated nucleoli of mouse ascites tumor cells. PMID- 4303999 TI - Primary infection of herpes simplex causing necrotic cervicitis. PMID- 4303998 TI - Tertiary structure determinants in transfer RNA. I. Pseudouridine. PMID- 4304000 TI - Studies on glutamic oxalacetic transaminase in the rat. 3. Hormonal control of isoenzyme levels in liver by the pituitary-adrenal system. PMID- 4304001 TI - [Control of adrenal medulla function by the adrenal cortex]. PMID- 4304002 TI - Three different midpoint oxidation-reduction potentials of cytochrome oxidase from bovine heart muscle. PMID- 4304003 TI - Biochemistry of shellfish lipids. IX. Enzymatic hydrolysis of ceramide 2 aminoethylphosphonate and sphingoethanolamine. PMID- 4304004 TI - Radiological differentiation between Wilm's tumour and neuroblastoma in abdominal masses. PMID- 4304005 TI - Cytomegalic inclusion disease. PMID- 4304006 TI - Separation of toad venom constituents on silica gel impregnated glass filter paper. PMID- 4304007 TI - EAN as a model for idiopathic polyneuritis. PMID- 4304008 TI - Neurofibrillary degeneration induced by Vinca alkaloids: clinical and experimental. PMID- 4304009 TI - Reversal of sleep-waking cycle: effect on sleep stage pattern and certain neuroendocrine rhythms. PMID- 4304010 TI - Presynaptic neuromuscular inhibition by delta-aminolevulinic acid, a porphyrin precursor. PMID- 4304011 TI - Hereditary neuropathy manifested by pressure palsies--a Schwann cell disorder? PMID- 4304012 TI - Polyneuropathy in the osteosclerotic form of multiple myeloma. PMID- 4304013 TI - Intranuclear inclusions in bovine embryo cell cultures infected with bovine virus diarrhoea-mucosal disease virus. PMID- 4304014 TI - Biochemistry of functional neural crest tumors. PMID- 4304015 TI - A semiautomated method which does not require digestion for the determination of serum thyroxine iodine (T4). PMID- 4304016 TI - Demonstration of glucagon in islet cell adenomas of the pancreas by immunofluorescent technic. PMID- 4304017 TI - Is conservative therapy ever justified in stage I (IA) cancer of the ovary? PMID- 4304018 TI - [A median cervical cyst with squamous epithelial foci and partly atypical thyroid tissue]. PMID- 4304019 TI - The endocrine function of the pancreas. PMID- 4304020 TI - Somatic sensation. PMID- 4304021 TI - In vitro evaluation of an acidulated phosphate fluoride prophylaxis paste. PMID- 4304022 TI - Potassium dependent phosphatase in bovine parotid gland. PMID- 4304023 TI - Tumors of the minor salivary glands. A report of 46 cases. PMID- 4304024 TI - Pleomorphic lymphoma and gastric adenocarcinoma (collision neoplasm) associated with monoclonal macroglobulinemia and amyloidosis. A case report. PMID- 4304025 TI - Combination chemotherapy using cyclophosphamide, vincristine, methotrexate and 5 fluorouracil in solid tumors. PMID- 4304026 TI - Intra-epidermal eccrine poroma: a histochemical and enzyme-histochemical study. PMID- 4304027 TI - Factors influencing distribution of Ultra Fluid Lipiodol (U.F.L.) following intrathyroid injection. PMID- 4304028 TI - Adenoid cystic carcinoma (cylindroma) of the trachea: case report with 9-year follow-up. PMID- 4304029 TI - [Pathogenesis of the polyradiculoneuritic syndrome and its treatment with ACTH. On the differential diagnosis of diseases simulating poliomyelitis]. PMID- 4304030 TI - Gero J: Range of the sympathetic control of the dog femoral artery. PMID- 4304031 TI - Thyrotropin release in vitro: stimulation by cyclic 3',5'-Adenosine monophosphate. PMID- 4304032 TI - Activation of skeletal adenyl cyclase by parathyroid hormone in vitro. PMID- 4304033 TI - Hypercalcemic and hypophosphatemic effects of dibutyryl cyclic AMP in rats after parathyroidectomy. PMID- 4304034 TI - Inhibition of lactation and luteal function in postpartum rats by hypothalamic implantation of prolactin. PMID- 4304035 TI - Comparison of assays for corticotrophin-releasing activity. PMID- 4304036 TI - Red cell agglutination kinetics: a method for automatic recording with the fragiligraph. PMID- 4304037 TI - On the storage and mobilization of organic resources in the hepatopancreas of a crab (Paratelphusa hydrodromus). PMID- 4304038 TI - Pressor response to angiotensin I during cardio-pulmonary bypass. PMID- 4304039 TI - Regional blood flows during desynchronized sleep in the cat. PMID- 4304040 TI - [Studies on the organotropism of the carcinogenic effect of N-nitroso-N methylurea (NMU) in rats]. PMID- 4304041 TI - 'Spontaneous' occurrence of Yaba tumor in a monkey colony. PMID- 4304042 TI - The effect of estrogen and castration on a spontaneous pancreatic islet change in rats. PMID- 4304043 TI - Antiviral activity of certain substituted purine and pyrimidine nucleosides. PMID- 4304044 TI - Cranial nerve disease. PMID- 4304045 TI - The chiasmal syndrome. PMID- 4304046 TI - Investigations on the adrenocortical function of normal dogs. PMID- 4304047 TI - The production of antibodies to porcine corticotrophin and to Synacthen. PMID- 4304049 TI - Inhibition of norepinephrine re-uptake by angiotensin in brain. PMID- 4304048 TI - Hormonal control of glycerolphosphate dehydrogenase in the rat brain. PMID- 4304050 TI - Reinnervation of spinal cord by cholinergic neurons. PMID- 4304051 TI - Analysis of slow inhibitory postsynaptic potential of bullfrog sympathetic ganglion. PMID- 4304052 TI - Cytomegalovirus infection after renal transplantation. Report of a case with viremia and atypical lymphocytosis. PMID- 4304053 TI - Immunization against Marek's disease using a live attenuated virus. PMID- 4304055 TI - Comparison of the diagnostic accuracy of liver scans, liver function tests and liver biopsies. PMID- 4304054 TI - Corticosteroids and ACTH in the management of the atopic child. PMID- 4304056 TI - Electron microscopy as an aid to the rapid identification of animal viruses. PMID- 4304057 TI - [Enzyme histochemical findings in muscle spindles]. PMID- 4304058 TI - [Enzyme histochemical findings in nuclear excavations of meningiomas]. PMID- 4304059 TI - [On the effect of trenimon on some histochemical reactions in the rat's testis]. PMID- 4304060 TI - [Sensitivity of the distribution area of the trigeminal nerve. Paths of transmission]. PMID- 4304061 TI - [The use of the oxidase test in the hygienic-bacteriological analysis of water]. PMID- 4304062 TI - Transmission of more than one sensory modality-message along a single axon. PMID- 4304063 TI - [Amebiasis, a challenge to the understanding of pathological mechanism]. PMID- 4304064 TI - [Simple apparatus to apply silica gel to microscopic slides]. PMID- 4304065 TI - [Electrolyte determination for examination of the function of the adrenal cortex]. PMID- 4304066 TI - [Comparative virulence of Entamoeba histolytica strains isolated from patients and different groups of carriers]. PMID- 4304067 TI - [On the mechanism of DDT resistance in insects. Changes in tissue respiration in houseflies (M. domestica) in the process of increasing DDT resistance]. PMID- 4304068 TI - [On a case of histiocytoma of the vulva with unusual trabecular structure]. PMID- 4304069 TI - [Electromyographic study of chronic uremic patients. Preliminary observations]. PMID- 4304070 TI - [Probable neurophysiological effects of psychopharmaca]. PMID- 4304071 TI - [Psychopharmacological effects on the data processing in the brain]. PMID- 4304072 TI - [Functional state of the leukocytes in healthy premature infants and in infants with cranial-brain birth trauma]. PMID- 4304073 TI - [Use of electroaerosols in the complex treatment of acute pneumonia in children given aid at home]. PMID- 4304074 TI - [The effectiveness of active planned prevention of rickets with videin D3 in a mountainous rural locality]. PMID- 4304075 TI - [The urocytogram in the menopause]. PMID- 4304076 TI - [Symptomatic nocturnal myoclonus]. PMID- 4304077 TI - [Clinico-polygraphic considerations on essential "slow sleep" narcolepsy]. PMID- 4304078 TI - [Excretion of 17-oxycorticosteroids in some infectious diseases]. PMID- 4304079 TI - [Significance of allergy in the pathogenesis of hepatites and cholecystoangiocholites]. PMID- 4304080 TI - [The mesenchymal defense reaction in the brain of the golden hamster after transplantation of human cerebral tumors]. PMID- 4304081 TI - Effect of the Finnish sauna-bath on the urinary excretion of 17-OH corticosteroids and blood eosinophil count in allergic and healthy persons. PMID- 4304082 TI - A comparative study of sleep parameters during pregnancy. PMID- 4304083 TI - A screening test for neuromuscular disturbances in adynamia episodica hereditaria. Clinical and electrophysiological study. PMID- 4304084 TI - Studies of bladder stone disease in Thailand. X. Effect of orthophosphate and nonfat dry milk supplementations on urine composition. PMID- 4304085 TI - Cell cultures of bovine embryonic skin: growth and characterization. PMID- 4304086 TI - Neutralization of canine herpesvirus by dog and human serums: a survey. PMID- 4304087 TI - [Is iodine poisoning after peroperative cholangiography possible?]. PMID- 4304088 TI - Functional classification of cell types of the anterior pituitary gland accomplished by electron microscopy. PMID- 4304089 TI - [Usefulness of intravenous administration of angiotensin as a diagnostic test for arterial renovascular hypertension]. PMID- 4304090 TI - The metabolism and biological activity of esterified vitamin D in the rat. PMID- 4304091 TI - Experimental adenovirus infection in calves. AB - Twenty-four dairy calves ranging in age from six to 15 weeks were divided so that 10 were inoculated with bovine adenovirus serotype 1 (BA-1), eight were inoculated with bovine adenovirus serotype 3 (BA-3), and six were inoculated with control tissue culture and fluids.Post-inoculation serum samples from most of the calves presented evidence of adenovirus infection, but none of the animals exhibited signs of respiratory or enteric disease. Histopathological examination of lung tissue was not considered to be specific for adenovirus pneumonia, but was characterized by peribronchial cuffing and slight aspiration pneumonia. BA-1 was not isolated from any of the inoculated calves, and BA-3 was only recovered from the feces of two animals. Reasons for the discrepancy between these results and those of other workers are considered, and the etiology of peribronchial cuffing is briefly discussed. PMID- 4304092 TI - Effect of ketone bodies and ACTH on the transmethylation reaction (S-adenosyl methionine independent system) in rats. I. PMID- 4304093 TI - [Chemotherapy of human virus infections. 3. Experence with chloroguanidine derivatives]. PMID- 4304094 TI - [Vaginal cytologic studies on the dosage-effect relation of conjugated estrogens (Presomen) in postmenopause women]. PMID- 4304095 TI - Movement of 131-I rose bengal out of the brain tumor bed. PMID- 4304096 TI - Chemotherapeutic agents. PMID- 4304097 TI - Influence of the anterior pituitary on the aldosterone secretory response to dietary sodium restriction in the rat. PMID- 4304098 TI - Replication of murine sarcoma virus-Harvey (MSV-H) in tissue cultures of virus induced sarcomas. PMID- 4304099 TI - A new DNA-exonuclease in cells infected with herpes virus: partial purification and properties of the enzyme. PMID- 4304100 TI - Mechanism of plaque inhibition of poliovirus possessing the d marker. PMID- 4304101 TI - The infectivity of polyoma virus DNA for mouse embryo cells in the presence of diethylaminoethyl-dextran. PMID- 4304102 TI - Studies on the nature and genetic control of an antigen in normal chick embryos which reacts in the COFAL test. PMID- 4304103 TI - Anti-viral activity of 5,6-dichloro-1-(2'-deoxy-beta-d ribofuranosyl)benzimidazole and related derivatives. PMID- 4304104 TI - Circulating interferon in mice infected with the lactate dehydrogenase-elevating virus. PMID- 4304105 TI - Inhibitory effect of interferon perparation on the development of foci of altered cells induced in vitro by mouse sarcoma virus. PMID- 4304106 TI - Mass in right upper quadrant of the abdomen. PMID- 4304107 TI - [Unusual kind and localization of salivary gland tumors in the retrotonsillar parapharyngeal space]. PMID- 4304108 TI - [Problems related to the etiology of virus hepatitis]. PMID- 4304109 TI - [Evaluation of enzymatic activity of cytochrome c preparations]. PMID- 4304110 TI - [Histochemical research on the role of enzymatic hydrolysis in the appearance of otosclerosis]. PMID- 4304111 TI - [On Pelomyxa palustris Greeff]. PMID- 4304112 TI - [Extended semicastration, lymphadenectomy and extended lymphadenectomy, radiotherapy and cystostatic triple-drug interval therapy of germinal testicular neoplasms]. PMID- 4304113 TI - [Study on pertussis using nerve tissue culture. 1. Study of the influence of solution containing pertussis organisms on cultu.ed nerve elements]. PMID- 4304114 TI - [Study on pertussis using nerve tissue culture. 2. Study on the influence of pertussis toxin on cultured nerve elements]. PMID- 4304115 TI - [On changes in plasma free 11-hydroxycorticosteroids values after continuous administration of ACTH in infants. 1. Plasma free 11-hydroxycorticosteroids values following continuous administration of ACTH in health infants]. PMID- 4304116 TI - [On changes in plasma free 11-hydroxycorticosteroids value following continuous administration of ACTH in infants. 2. Plasma free 11-hydroxycorticosteroids values following continuous administration of ACTH in various pediatric diseases]. PMID- 4304117 TI - [Effect of pretreatment by immunity adjuvants on the multiplication of foot-and mouse disease virus in adult mouse]. PMID- 4304118 TI - [Inactivation by U.V., X and gamma radiation of 2 properties of SV-40 virus: infectivity and induction of early nuclear antigen]. PMID- 4304119 TI - [Demonstration of gastro-secretogogue activity of pancreatic origin. Apropos of a case of insinoma and 3 cases of Zollinger-Ellison syndrome]. PMID- 4304120 TI - The effects of air pollutants on mucociliary clearance. PMID- 4304121 TI - Some observations on Clostridium perfringens strains isolated in Iran. PMID- 4304122 TI - [Isolation of a bacteriophage active for Welchia agni, var. Wilsdoni "Type D"]. PMID- 4304123 TI - [Changes of the antigenic structure of W. agni var. paludis C at the time of its transformation in anatoxine]. PMID- 4304124 TI - [Toxi-infections provoked by food infected by anaerobic bacteria especially by W. perfringens and W. agni]. PMID- 4304125 TI - Study of the role of Clostridia in swine gastroenteritis. PMID- 4304126 TI - Intestinal Clostridium perfringens in arthritis and parakeratosis induced by dietary factors. Experimental studies in pigs. PMID- 4304127 TI - [Contribution to the etiological study of Welchii infections in animals]. PMID- 4304128 TI - The occurrence in Denmark of necrotizing enteritis in piglets caused by Clostridium perfringens type C. PMID- 4304129 TI - Typing of the foot-and-mouth disease virus. Cumulative Quarterly report. PMID- 4304130 TI - Typing of the foot-and-mouth disease virus. Results of diagnosis and typing of foot-and-mouth disease virus. PMID- 4304131 TI - Melanotic progonoma in an African infant. PMID- 4304132 TI - An EPR study of live and dead Drosophila adults under aerobic conditions. PMID- 4304133 TI - [Bacteriology of whooping cough. Identification of Bordetellas isolated from children in Rio de Janeiro]. PMID- 4304134 TI - Immunobiological relationship of goat pox and sheep pox viruses. PMID- 4304135 TI - Gas-liquid chromatography of ergocalciferol and cholecalciferol in nanogram quantities. PMID- 4304136 TI - [Thin layer chromatography of n-alkyl tin binding to siliconized silica gel]. PMID- 4304137 TI - Genetic influence on the development of renal hypertension in parabiotic rats. Evidence for a humoral factor. AB - The effects of several renal manipulations including uninephrectomy, unilateral renal artery constriction, and a combination of these two (Goldblatt procedure) were studied in two strains of rats with opposite constitutional predispositions to experimental hypertension. The protective value of intact renal tissue to protect against hypertension was shown to be genetically determined. The Goldblatt procedure carried out on only one member of a parabiotic pair induced hypertension in this operated rat but significant hypertension developed in the intact partner only when the operated animal belonged to the strain predisposed to hypertension. It was speculated that there were qualitative differences in the pressor signals of the two strains of rats. In the strain genetically predisposed to hypertension there are at least two pressor principles: (a) one which is common to both strains, not transmittable via the parabiosis junction and presumably related to the renin-angiotensin system; and (b) a second which is specific for the hypertension-prone strain and can be transmitted through the parabiosis junction. This transmittable agent is probably identical with the factor that produces salt hypertension and is associated with the salt-excreting mechanism. PMID- 4304138 TI - The occurrence and properties of leukocytosis and lymphocytosis-stimulating material in the supernatant fluids of Bordetella pertussis cultures. AB - 1. Leukocytosis- and lymphocytosis-stimulating activity was present in fluid cultures of B. pertussis. The activity was found primarily in the culture supernatant fluid. 2. The sequential changes in the leukocyte response were similar to those previously observed following injection of intact bacteria into mice. 3. Activity was destroyed by heat and was diminished, but not abolished, by prolonged treatment with proteolytic enzymes. 4. A water-insoluble fraction of the culture supernatant fluid was isolated which contained virtually all of the activity. The specific activity was more than 100-fold greater than that of the intact bacteria, and injection of microgram quantities produced a response. 5. The distribution of histamine-sensitizing factor followed that of leukocytosis stimulating activity. In contrast, mouse protective antigen was localized to the bacterial pellet. PMID- 4304140 TI - Peripheral nerve syndromes. PMID- 4304141 TI - Forensic medicine. PMID- 4304139 TI - Studies on the entry of viruses into the central nervous system of mice via the circulation. Differential effects of vasoactive amines and CO2 on virus infectivity. AB - The inhalation of CO(2) exerted a selective action on the entry of viruses into the CNS of mice via the circulation. In 6 wk old animals, the infectivity of poliovirus, vaccinia, and vesicular stomatitis viruses was enhanced, whereas the entry of herpesviruses and of a neurotropic influenza virus was not affected. However, in 3 to 4 wk old mice, inhalation of the gas enhanced the infectivity of all the viruses. To explain the relationship of age to the animals' response to CO(2), it was proposed that CO(2) inhalation, by increasing the rate of cerebral blood flow, served to increase the exposure of some extraneural cell(s) to virus, possibly the cerebrovascular endothelial cell, in which virus replicated and reached the brain parenchyma by direct extension of the infectious process. Consequent to maturation, the postulated target cell developed resistance to certain viruses, while its susceptibility to others remained unchanged. Inoculation of adrenalin or serotonin simultaneously with virus into the circulation enhanced the CNS infectivity of all the viruses tested in both 4 wk and 6 wk age groups of mice. The enhancing effects were completely inhibited by the action of an alpha-adrenergic blocking agent; it was therefore concluded that hemodynamic changes produced by the contractile response of the smooth muscle cells in the vessel walls mediated the enhancing effect. It was suggested that a vasopressor response invoked in the peripheral vessels, with a consequent increase in cerebral blood flow, increased virus dosage to the CNS. In addition, a direct effect of the vasoactive amine on the cerebral vessels, resulting in the disruption of an anatomical "barrier", was considered as a contributory factor in increasing the transfer of virus to the CNS from the circulation. PMID- 4304142 TI - [Congenital generalized cytomegalic inclusion disease, diagnosed during life]. PMID- 4304143 TI - [A limited form of adenomatosis of the lungs]. PMID- 4304144 TI - Eye movement ativity during sleep and intellectual function in mental retardation. AB - A positive relation was found between the amount of eye movement during rapid-eye movement or paradoxical sleep and estimates of intellectual level in a group of retarded adults. This result supports the hypothesis that during sleep the brain carries out processes important for cognitive function. PMID- 4304145 TI - [Autoimmune hemolytic anemia with lymphatic nodules in the bone marrow]. PMID- 4304146 TI - [An electron microscope study of the cell occlusions of macrophage type found in the synovial fluid during Behcet's syndrome]. PMID- 4304147 TI - [Acute traumatic tetraplegia without bone lesions. (Study of 40 cases)]. PMID- 4304148 TI - [Mucopolysaccharidosis of Hurler type I without mental retardation in an adult and his two cousins]. PMID- 4304149 TI - [Budd-Chiari's syndrome with cranial venous thrombosis during Marchiafava-Micheli hemolytic disease]. PMID- 4304150 TI - [Therapy of pulmonary stenosis with an intact intraventricular septum]. PMID- 4304151 TI - Effects of vasoactive agents on intestinal blood flow and motility in the dog. PMID- 4304152 TI - Preventive psychiatry for the family: theory, approaches, and programs. PMID- 4304153 TI - Glioblastoma multiforme: its treatment and some factors effecting survival. PMID- 4304154 TI - Antagonistic actions between dibutyryl adenosine-3',5'-cyclic monophosphate and insulin on the metabolism of the surviving rat diaphragm. PMID- 4304155 TI - The role of anticodon in the acceptor function of tRNA. PMID- 4304156 TI - Influence of metal ions on the orthophosphatase and inorganic pyrophosphatase activities of human alkaline phosphatase. PMID- 4304157 TI - A product-inhibition study of the mechanism of mitochondrial octanoly-coenzyme A synthetase. AB - By a study of the product-inhibition kinetics of the octanoyl-CoA synthetase from ox liver mitochondria, evidence was obtained consistent with the hypothesis that the enzyme reacts by a Bi Uni Uni Bi Ping Pong type of mechanism in which the order of addition and evolution of substrates and products is CoA, octanoate, octanoyl-CoA, ATP, PP(i) and AMP. There is also evidence that more than one molecule of CoA can add to the enzyme and that it may act as an allosteric activator. PMID- 4304158 TI - Temperature and the regulation of enzyme activity in poikilotherms. Properties of rainbow-trout fructose diphosphatase. AB - 1. The properties of fructose diphosphatase from the liver of rainbow trout (Salmo gairdnerii) were examined over the physiological temperature range of the organism. 2. Saturation curves for substrate (fructose 1,6-diphosphate) and a cofactor (Mg(2+)) are sigmoidal, and Hill plots of the results suggest a minimum of two interacting fructose 1,6-diphosphate sites and two interacting Mg(2+) sites per molecule of enzyme. 3. Mn(2+)-saturation curves are hyperbolic, and the K(a) for Mn(2+), which inhibits the enzyme at high concentrations, is 50-100-fold lower than the K(a) for Mg(2+). 4. Fructose diphosphatase is inhibited by low concentrations of AMP; this inhibition appears to be decreased and reversed by increasing the concentrations of Mg(2+) and Mn(2+). Higher concentrations of AMP are required to inhibit the trout fructose diphosphatase in the presence of Mn(2+). 5. The affinities of fructose diphosphatase for fructose diphosphate and Mn(2+) appear to be temperature-independent, whereas the affinities for Mg(2+) and AMP are highly temperature-dependent. 6. The pH optimum of the enzyme depends on the concentrations of Mg(2+) and Mn(2+). In addition, pH determines the K(a) for Mg(2+); at high pH, K(a) for Mg(2+) is lowered. 7. The enzyme is inhibited by Ca(2+) and Zn(2+), and the inhibition is competitive with respect to both cations. 8. The possible roles of these ions and AMP in the modulation of fructose diphosphatase and gluconeogenic activity are discussed in relation to temperature adaptation. PMID- 4304159 TI - Synthesis of 10,11-dihydrofarnesyl pyrophosphate from 6,7-dihydrogeranyl pyrophosphate by prenyltransferase. AB - The syntheses of 6,7-dihydrogeraniol and of its pyrophosphate are described. It is shown that this analogue of geranyl pyrophosphate is a substrate for liver prenyltransferase and that the product synthesized by this enzyme from it and isopentenyl pyrophosphate is 10,11-dihydrofarnesyl pyrophosphate. The K(m) value for 6,7-dihydrogeranyl pyrophosphate was determined to be 1.11+/-0.19mum as compared with 4.34+/-1.71mum for geranyl pyrophosphate. The maximum reaction velocity with the artifical substrate was, however, only about one-fourth of that observed with geranyl pyrophosphate. The binding of isopentenyl pyrophosphate to the enzyme was not affected by the artificial substrate. PMID- 4304160 TI - Analogues of geranyl pyrophosphate as inhibitors of prenyltransferase. AB - Six analogues of geranyl pyrophosphate (the monophosphates of geraniol and tetrahydrogeraniol, and the pyrophosphates of nerol, octan-1-ol, tetrahydrogeraniol and citronellol) were synthesized, and were found to be inhibitors of pig liver prenyl- (geranyl-)transferase. The effects of each analogue were analysed in kinetic experiments, which showed the pyrophosphates of citronellol, tetrahydrogeraniol and octan-1-ol to be the most potent inhibitors. The results are interpreted to support a previous hypothesis that the main forces in the binding of substrates to prenyltransferase are non-specific lipophilic forces and a pyrophosphate-binding force. PMID- 4304162 TI - Systemic corticosteroids and folic acid antagonists in the treatment of generalized pustular psoriasis. Evaluation and prognosis based on the study of 104 cases. PMID- 4304161 TI - A comparison of the properties of the phosphofructokinases of the fat body and flight muscle of the adult male desert locust. AB - 1. Phosphofructokinase was isolated, and partially purified by ammonium sulphate fractionation, from the fat body and flight muscle of the desert locust. 2. Ammonium sulphate appears to stabilize the enzymes, but does not activate them. 3. Both flight-muscle and fat-body enzymes give sigmoidal hexose monophosphate concentration-activity curves, which are characteristic of regulatory enzymes. 4. At low ATP concentrations both the enzyme activities increase rapidly with increasing ATP concentrations, but above an optimum concentration ATP becomes inhibitory. This optimum concentration is 0.2mm for the fat-body enzyme and 0.1mm for the flight-muscle enzyme. 5. AMP activates both the enzymes; half-maximal activation occurs at 10mum in each case, the effect being independent of substrate concentration. 6. 3',5'-(cyclic)-AMP (0.5mm) and P(i) (1mm) activate the flight-muscle enzyme, but have no effect on the fat-body enzyme. 7. FDP (1mm) inhibits both enzymes, and with the flight-muscle enzyme this inhibition is increased by increasing the ATP concentration. 8. Citrate, phosphoenolpyruvate and alpha-glycerophosphate have no effect on either enzyme under the assay conditions used. 9. The properties of phosphofructokinases from the locust are compared with those of phosphofructokinases from other sources. PMID- 4304163 TI - Afferent respiratory pathways in the avian vagus. PMID- 4304164 TI - Pyruvate metabolism in peripheral neuropathy. PMID- 4304165 TI - Age determination of bone fragments. PMID- 4304166 TI - Essential fatty acid dificiency and the testis: lipid composition and the effect of preweaning diet. PMID- 4304167 TI - Hematin formation and pancreatitis. PMID- 4304168 TI - Degradation of (131 I) insulin and inhibition of post-heparin lipolytic activity by collagenase. PMID- 4304169 TI - Detailed analysis of neuromuscular transmission in a patient with the myasthenic syndrome sometimes associated with bronchogenic carcinoma. PMID- 4304170 TI - Clinicopathologic conference. Renal insufficiency following renal transplant. Resume of case. PMID- 4304171 TI - [Modifications of lymphocyte recirculation induced by antigenic stimulation, ACTH and cortisone]. PMID- 4304172 TI - [Liver scanning and angiography of the hepatic artery]. PMID- 4304173 TI - Evaluation of local anaesthetics in man. Studies on the blocking effects of some local anaesthetics and their late effects on nerve transmission. PMID- 4304174 TI - Regulation of peripheral circulation in anaesthesia. PMID- 4304175 TI - Isoelectric fractionation, analysis, and characterization of ampholytes in natural pH gradients. VII. The isoelectric spectra of fungal laccase A and B. PMID- 4304176 TI - Conversion of alpha-L-angiotensin amide to beta-L-angiotensin during enzymatic degradation. PMID- 4304177 TI - [Experimental study of the toxicity of triiodoferous contrast media used in arteriography]. PMID- 4304178 TI - Double blind evaluation of the haemostatic effect of adrenochrome monosemicarbazone, conjugated oestrogens and epsilonaminocaproic acid after adenotonsillectomy. PMID- 4304179 TI - [Correlation of brain scans and the morphology of brain tumors]. PMID- 4304180 TI - Radiometric method for determination of glucose 6-phosphatase activity in liver. PMID- 4304181 TI - Determination of enzymatic activity in polyacrylamide gels. I. Enzymes catalyzing the conversion of nonreducing substrates to reducing products. PMID- 4304182 TI - Vitiligo. HepATOMA. PMID- 4304183 TI - [Positive myelography using ethylmonoiodostearate]. PMID- 4304184 TI - [The chemotherapy of solid tumors in childhood]. PMID- 4304185 TI - [Characteristics and treatment of choriocarcinoma and related trophoblastic tumors in women]. PMID- 4304186 TI - Tumor response to phenylalanine-tyrosine-limited diets. PMID- 4304187 TI - Glycolysis-dependent exchange of diphosphopyridine nucleotide-3H in red blood cells and ascites cells. PMID- 4304188 TI - Resolution and reconstitution of the mitochondrial electron transport system. II. Reconstitution of succinoxidase from individual components. PMID- 4304189 TI - The metabolism of isolated fat cells. 8. Amino acid transport in ghosts. PMID- 4304191 TI - The estimation of kinetic constants for the lactate dehydrogenase system by the use of integrated rate equations. PMID- 4304190 TI - Human hypoxanthine phosphoribosyltransferase. II. Kinetics and chemical modification. PMID- 4304192 TI - Configuration of the ketosidic bond of sialic acid. PMID- 4304193 TI - Importance of sulfhydryl groups for lipolytic action in the isolated fat cell. PMID- 4304194 TI - Presence and location of an unusual amino acid, epsilon-N-trimethyllysine, in cytochrome c of wheat germ and Neurospora. PMID- 4304195 TI - Intraneural lipoma of the median nerve. Report of two cases and review of the literature. PMID- 4304196 TI - Effect of sodium deficiency on adrenal sensitivity to angiotensin and ACTH in the rat. PMID- 4304197 TI - The stability of endogenous and exogenous corticotrophin in rat plasma as established by a bioassay in intact rats. PMID- 4304198 TI - Application of the coated charcoal separation method to the radio-immunoassay of plasma corticotrophin. PMID- 4304199 TI - The plasma corticotrophin response to insulin hypoglycaemia, lysine-vasopressin and metyrapone in pigs. PMID- 4304200 TI - Problems in the determination of urinary 1-oxygenated steroids. PMID- 4304201 TI - The possible role of adenyl cyclase in thyrocalcitonin release. PMID- 4304203 TI - [Physiological and chemical processes in the development and transmission of neural stimulations]. PMID- 4304202 TI - Active calcium and strontium transport in human erythrocyte ghosts. AB - Both calcium and strontium could be transported actively from erythrocytes if adenosine triphosphate, guanosine triphosphate, or inosine triphosphate were included in the hypotonic medium used to infuse calcium or strontium into the cells. Acetyl phosphate and pyrophosphate were not energy sources for the transport of either ion. Neither calcium nor strontium transport was accompanied by magnesium exchange, and the addition of Mg(++) to the reaction medium in a final concentration of 3.0 mmoles/liter did not promote the transport of either ion. In the absence of nucleotide triphosphates, the addition of 1.5 mmoles/liter of Sr(++) to the reaction solution did not bring about active calcium transport and similarly 1.5 mmoles/liter of Ca(++) did not bring about active strontium transport. The inclusion of 1.5 mmoles/liter of Ca(++) or Sr(++) in the reaction medium did not interfere with the transport of the other ion when the erythrocytes were infused with adenosine triphosphate. PMID- 4304204 TI - [Resistance in vitro of Psudomonas aeruginosa to gentamicin compared with colistin and polymyxin B]. PMID- 4304205 TI - [Fulminating course in primary liver cell carcinoma]. PMID- 4304206 TI - Neonatal canine herpesvirus infection: a review of present knowledge. PMID- 4304207 TI - [Several indices of the state of neurohumoral regulation in bronchial asthma in children of preschool and early school age]. PMID- 4304208 TI - [Effect of Bordetella pertussis on the lymphatic tissue of mice. IV. The effect of Bordetella pertussis on the kinetics of antibody formation in mice treated with cyclophosphamide]. PMID- 4304209 TI - [Experience in the use of the ACM-2 apparatus for analgesic purposes]. PMID- 4304210 TI - Stereotaxic transsphenoidal biopsy and cryosurgery of pituitary tumors. PMID- 4304211 TI - Decreased glycolytic enzyme activity in epiphyseal cartilage of cortisone-treated rats. PMID- 4304212 TI - Beta-aspartylhydroxamic acid: its action as a feedback inhibitor and a repressor of asparagine synthetase in Lactobacillus arabinosus. PMID- 4304214 TI - [On cylindroma of the breast and the cylindromatous appearance of various mastopathies]. PMID- 4304213 TI - The effects of dietary protein on the hepatic enzymes of serine metabolism in the rabbit. PMID- 4304215 TI - [Rare observation of a multiple regional glomus tumor of the limbs]. PMID- 4304216 TI - [Clinico-pathological conference. Cholangiocarcinoma with hypercalcemia and hypophosphatemia]. PMID- 4304217 TI - Plasma cortisol and response to corticotrophin in airways obstruction. PMID- 4304218 TI - Today's drugs. PMID- 4304219 TI - [On the efferent pathway of reflex adrenaline secretion evoked by stimulation of forelimb afferent nerves]. PMID- 4304220 TI - Aftercare for mentally abnormal offenders in the Netherlands. PMID- 4304221 TI - Mechanism of renal hypertension. Utilization of phentolamine (Regitine) test in essential, renal and angiotensin induced hypertension. PMID- 4304222 TI - Biochemical basis of obligate autotrophy in Nitrosomonas europaea. AB - The specific activities of isocitric dehydrogenase, alpha-ketoglutaric dehydrogenase, succinic dehydrogenase, malic dehydrogenase, and reduced nicotinamide adenine dinucleotide (NADH) oxidase were determined in extracts of Nitrosomonas europaea and compared with the corresponding values for Anacystis nidulans and autotrophically grown Hydrogenomonas eutropha. In common with other obligate autotrophs and in contrast to facultative autotrophs, Nitrosomonas extracts lacked alpha-ketoglutaric dehydrogenase and KCN-sensitive NADH oxidase activity and had low succinic dehydrogenase activity. The Nitrosomonas NADH oxidase appeared to be of the peroxidase type. PMID- 4304223 TI - Conversion of glucose-1-phosphate to 3-keto-glucose-1-phosphate by cells of Agrobacterium tumefaciens. AB - Incubation of resting cells of Agrobacterium tumefaciens with glucose-1-phosphate resulted in the accumulation of a new sugar phosphate in the suspending medium. Approximately 80% of the glucose-1-phosphate consumed was converted to the new compound, which was identified as alpha-d-ribo-hexopyranosyl-3-ulose-1-phosphate (3-ketoglucose-1-phosphate). Both utilization of glucose-1-phosphate and accumulation of 3-ketoglucose-1-phosphate were inhibited by 2,4-dinitrophenol, polymyxin, and d-glucose, which are inhibitors of the glucoside transport system of this bacterium but are not inhibitors of d-glucoside-3-dehydrogenase, which is the 3-ketoglucose-1-phosphate-forming enzyme. Consequently, it was concluded that glucose-1-phosphate penetrates into intracellular space by means of an active transport system. The glucose-1-phosphate is converted to 3-ketoglucose-1 phosphate by d-glucoside-3-dehydrogenase, and the 3-ketoglucose-1-phosphate formed reaches the extracellular space by passing through the surface layer of the bacterium. PMID- 4304224 TI - Reduced nicotinamide adenine dinucleotide oxidase and alpha-ketoglutaric dehydrogenase activity by Thiobacillus thiooxidans. PMID- 4304225 TI - Control of gluconeogenesis in liver. 3. Effects of L-lactate, pyruvate, fructose, glucagon, epinephrine, and adenosine 3',5'-monophosphate on gluconeogenic intermediates in the perfused rat liver. PMID- 4304226 TI - Mammalian metabolism of glutaric acid. PMID- 4304227 TI - Coenzyme binding to L-alpha-glycerophosphate dehydrogenase. PMID- 4304228 TI - The biosynthesis of folic acid. IX. Purification and properties of the enzymes required for the formation of dihydropteroic acid. PMID- 4304229 TI - The effect of deuterium oxide on the fluorescence of reduced nicotinamide adenine dinucleotide free in solution and in complexes with liver alcohol dehydrogenase. PMID- 4304230 TI - Biosynthesis of a cell wall glucomannan in mung bean seedlings. PMID- 4304231 TI - The amino acid composition and other properties of thermostable glyceraldehyde 3 phosphate dehydrogenase from Bacillus stearothermophilus. PMID- 4304232 TI - The separation and partial characterization of L-histidinol phosphatase and an alkaline phosphatase of Saccharomyces cerevisiae. PMID- 4304233 TI - Cushing's syndrome and adrenal medullary insufficiency with bilateral adrenal calcification. PMID- 4304234 TI - The influence of mitomycin C, actinomycin D and ultraviolet light on the replication of the viruses of foot-and-mouth disease and vesicular stomatitis. PMID- 4304235 TI - Independent action of antidiuretic hormone, theophylline and cyclic 3',5' adenosine monophosphate on cell membrane permeability in frog skin. AB - 1. The effects of antidiuretic hormone (ADH), theophylline and cyclic 3',5' adenosine monophosphate (AMP) on membrane potentials in frog skin have been investigated.2. Membrane potentials across the outer and inner facing membranes were recorded in both normal and current clamped skins. In the latter condition active transport of sodium had been abolished by ouabain or metabolic inhibitors, but ionic gradients were maintained by passing current through the skin from the inside.3. ADH increases the potential across the outer facing membranes and reduces the skin resistance. The results are consistent with ADH causing an increase in permeability of the outer facing membranes to sodium ions.4. Theophylline reduces the skin potential by reducing specifically the potential across the outer facing membranes. At the same time the skin resistance is reduced. Theophylline acts by increasing the permeability of the outer facing membranes to chloride ions.5. Cyclic 3',5'-AMP causes a biphasic potential change accompanied by an increase in skin resistance.6. Metabolic inhibitors block the response of the skin to ADH but not to theophylline.7. Separate explanations for the increase in sodium transport by ADH, theophylline and cyclic 3',5'-AMP are discussed. It is not necessary to involve cyclic AMP in order to explain the effects of either ADH or theophylline. PMID- 4304236 TI - Ultrastructure and function of the chromaffin cells in the superior cervical ganglion of the rat. PMID- 4304237 TI - Natural herpes simplex infection in the owl monkey (Aotus trivirgatus). PMID- 4304238 TI - Segmental demyelinization in Dejerine-Sottas disease: light, phase-contrast, and electron microscopic studies. PMID- 4304239 TI - Experimental hypertrophic neuropathy: change in fascicular area and fiber spectrum after acute crush injury. PMID- 4304240 TI - [Serologic comparison of cytomegaloviruses among Japanese and American strains]. PMID- 4304241 TI - [Contribution to the laboratory diagnosis of reovirus infections]. PMID- 4304242 TI - [Viral hepatitis and occupational disease with special reference to our research in the examination points and hospitals of Ruhr miners]. PMID- 4304243 TI - [Peculiar neurologic and urologic aspects of tumors developing in spina bifida occulta in adults and older children. Apropos of 2 cases of lumbosacral lipoma surgically treated]. PMID- 4304244 TI - An evaluation of the remote effects of cancer on the nervous system. PMID- 4304245 TI - A retrospective study of sarcoma of the breast and the results of treatment. PMID- 4304246 TI - Regional cerebral blood flow in tumour patients. PMID- 4304247 TI - The regional circulation in brain tumors. PMID- 4304248 TI - Tissue hypoxia: cellular oxygen requirements with special regard to the in vivo pO2 of the brain. PMID- 4304249 TI - Active center of DNA polymerase. PMID- 4304250 TI - 25-Hydroxycholecalciferol: stimulation of bone resorption in tissue culture. AB - 25-Hydroxycholecalciferol stimulates release of previously incorporated calcium 45 from fetal rat bones in doses of 0.9 to 27 units per milliliter. This effect cannot be produced by much larger doses of vitamin D(3). Comparison of stimulation of bone resorption by 25-hydroxycholecalciferol and parathyroid hormone reveals similarities with respect to time course, dose-response slope, and inhibition by calcitonin. PMID- 4304252 TI - [On the occasion of 2 cases of hyperthyreosis in children]. PMID- 4304251 TI - Allantoinase: association with amphibian hepatic peroxisomes. AB - Differential and density-gradient centrifugation studies have estaiblished an associatiotn between allaintoinase and peroxisomes from the liver of the frog Rana pipiens. The presence of allantoincase in the peroxisome indicates. a iricolytic function for this orgainelle in the liver of amphibians. PMID- 4304253 TI - [Histochemical behavior of isocitrate, succinate and malate dehydrogenase and of cytochrome oxidase in rat organs following total body irradiation]. PMID- 4304254 TI - Severe occult juvenile myasthenia gravis responsive to long-term corticosteroid therapy. PMID- 4304255 TI - [On pathogenesis and treatment of allergic respiratory diseases in young children]. PMID- 4304256 TI - Bronchial asthma with adreno-cortical hypofunction. PMID- 4304257 TI - All-night sleep studies of acute schizophrenics. PMID- 4304258 TI - The growth of varicella-zoster virus in tissue fragments. PMID- 4304259 TI - Effect of endotoxin from Serratia marcescens on the permeability of vessels in hepatomas and carrageenin granulomas of rats. PMID- 4304260 TI - Insulin secretion by the ovine fetus in utero. PMID- 4304261 TI - Pituitary-adrenal stimulating effect of superior mesenteric venous constriction. PMID- 4304262 TI - Assay of corticotropin-releasing factors by injection into the anterior pituitary of intact rats. PMID- 4304263 TI - Effects of thyroxine upon biosynthesis of flavin mononucleotide and flavin adenine dinucleotide. PMID- 4304264 TI - Stimulation of gluconeogenesis in rat liver slices by epinephrine and glucocorticoids. PMID- 4304265 TI - Plasma corticosteroid response to stress in four species of wild mice. PMID- 4304266 TI - Adrenocortical function in monkeys after forebrain removal or pituitary stalk section. PMID- 4304267 TI - Brief hospital treatment of schizophrenia--early results of a multiple-hospital study. PMID- 4304268 TI - Amebiasis, a familial disease. I. The food handler as a transmitter of amebiasis. PMID- 4304269 TI - Ameboma of colon and rectum. A report of 58 cases. PMID- 4304270 TI - Viruses and neoplasia. The search for viruses in human neoplasms. PMID- 4304271 TI - [Generation of angiotensin in vitro before and after binephrectomy in man]. PMID- 4304272 TI - [On the use of monoamine oxidase inhibitor benazid in autonomic ganglionitis]. PMID- 4304273 TI - [Benign neurogenic tumors of the lung]. PMID- 4304274 TI - [Plasma and urine renin concentration in patients with and without pathologic proteinuria]. PMID- 4304275 TI - [Enzyme histochemical studies on nucleoside phosphate and carbohydrate metabolism during cancerization of the rat liver with diethylnitrosamine (DENA) by measured oral application of the cancerogenic substance]. PMID- 4304276 TI - Electron microscopy and electron microscopic autoradiography of splenic cell cultures from mice with amyloidosis. PMID- 4304277 TI - [Clinical-virological characteristics of adenovirus infections in newborn infants]. PMID- 4304278 TI - [The clinical course of parainfluenzal diseases in children]. PMID- 4304279 TI - Increased synthesis of hyaluronic acid by a mouse cell line chronically infected with Rauscher leukaemia virus. PMID- 4304280 TI - [Irregular hepatectomy for primary cancer of the liver]. PMID- 4304281 TI - [Transmissibility of infectious ribonucleic acid from neurotropic foot-and-mouth disease virus from murine brains to the brains of small laboratory animals]. PMID- 4304282 TI - [Experimental study in rats of the effect of radon on the normal and dusted lung]. PMID- 4304283 TI - Biological effects of radiation-induced free radicals in fern spores. PMID- 4304284 TI - [The dominant infectious agents in the densely populated area of Korhogo and beyond in the north of the Ivory Coast]. PMID- 4304285 TI - Simultaneous determination of urinary estriol, pregnanediol, and pregnanolone by gas-liquid chromatography. PMID- 4304286 TI - A simple nonchromatographic determination of glycerophosphatide in serum. PMID- 4304287 TI - Altered pathways of urinary corticosteroid excretion in liver disease studied by a clinical laboratory method. PMID- 4304288 TI - [On the treatment of endocrinous crises]. PMID- 4304289 TI - Dynamics of cytopathic effect of Sendai virus with action of N1, N1 anhydrobis (beta-hydroxyethyl (biguanide) ABOB). PMID- 4304290 TI - [Electrical properties of neurons and synaptic transmission in sympathetic ganglia]. PMID- 4304291 TI - [Histochemistry of enzymes in developing neuroglia]. PMID- 4304292 TI - [Tomography of glomus tumors of the ear]. PMID- 4304293 TI - [Rapid procedure for subtraction in daily routine work]. PMID- 4304294 TI - [Rare bone dysplasias]. PMID- 4304295 TI - Sttudies on pyrocatechase. II. Electron spin resonance and other properties of iron in the active center. PMID- 4304296 TI - Effect of substrate on the conformation of myosin. PMID- 4304297 TI - Enzymatic joining of polynucleotides. VI. Activity of a synthetic adenylylated polydeoxynucleotide in the reaction. PMID- 4304298 TI - Nonpolar interactions of inhibitors with the nicotinamide adenine dinucleotide binding sites of L-alpha-glycerophosphate dehydrogenase. PMID- 4304299 TI - Studies on the adrenocorticotropic hormone-activated adenyl cyclase of a functional adrenal tumor. PMID- 4304300 TI - Influence of organic solutes on the reactions of oxidative phosphorylation. PMID- 4304301 TI - The role of deoxyribonucleic acid in ribonucleic acid synthesis. XVI. The purification and properties of ribonucleic acid polymerase from yeast: preferential utilization of denatured deoxyribonucleic acid as template. PMID- 4304302 TI - Digestive activity of lysosomes. 3. The digestion of lipids by extracts of rat liver lysosomes. PMID- 4304303 TI - Separation of a factor indispensable for coupled phosphorylation from the particulate fraction of Mycobacterium phlei. PMID- 4304304 TI - Monodehydroascorbic acid-transhydrogenase activity and coenzyme concentrations in tissues of ascorbic acid-deficient and control guinea pigs. PMID- 4304305 TI - [Epidemiology of liver cancer]. PMID- 4304306 TI - [Racial and regional characteristics of ESR spectra intensity of the human black hair]. PMID- 4304307 TI - [Electron microscope observations on inclusion bodies in swine pox]. PMID- 4304308 TI - Influence of electrical stimulation and lesion in limbic structure upon biosynthesis of adrenocorticoid in the rabbit. PMID- 4304309 TI - Influence of corticosterone implantation in limbic structure upon biosynthesis of adrenocortical steroid. PMID- 4304311 TI - Spleen or large left hepatic lobe? PMID- 4304310 TI - Pituitary ACTH release and avoidance behaviour of rats with cortisol implants in mesencephalic reticular formation and median eminence. PMID- 4304312 TI - [Antibiotic sensitivity of Clostridium perfringens strains]. PMID- 4304313 TI - [Krukenberg tumor (anatomo-clinical considerations on a case)]. PMID- 4304314 TI - [The alkaline phosphomonoesterase I in the tooth germ]. PMID- 4304315 TI - [Immunologic study of the cerebrospinal fluid proteins]. PMID- 4304317 TI - [Several problems concerning the etiologic mechanism of peripheral nerve diseases]. PMID- 4304316 TI - [A case of associated multiple sclerosis and cerebral glioblastoma]. PMID- 4304318 TI - [Peripheral neuritis--an experimental study]. PMID- 4304320 TI - [Peripheral nerve disorders in collagen diseases]. PMID- 4304319 TI - [Porphyria and peripheral nerve diseases]. PMID- 4304321 TI - [Amyloidosis and peripheral nerve diseases]. PMID- 4304322 TI - [Unusual cranial neuropathy--Garcin's syndrome and migrating, disseminated, multiple cranial neuropathy]. PMID- 4304323 TI - [Peripheral nerve diseases causing perforating ulcer and defects of extremities, with special reference to hereditary sensory radicular neuropathy]. PMID- 4304324 TI - [Peripheral neuropathy in malignant tumors]. PMID- 4304325 TI - Comparison of three rhesus groups for antibody patterns to some viruses: absence of active simian virus 40 transmission in the free-ranging rhesus of Cayo Santiago. PMID- 4304326 TI - Enzootic sendai infection in laboratory hamsters. PMID- 4304327 TI - Examination of various avian species for neutralizing antibody and susceptibility to rous sarcoma virus. PMID- 4304328 TI - Bluetongue in sheep: viral assay and viremia. PMID- 4304329 TI - Bluetongue in cattle: viremia. PMID- 4304330 TI - Enzymes of equine erythrocytes: changes during equine infectious anemia. PMID- 4304331 TI - Modification of foot-and-mouth disease viruses in primary dog kidney cell cultures. PMID- 4304332 TI - Some characteristics and developmental aspects of rat uridine diphosphogalactose 4-epimerase. PMID- 4304333 TI - Presence in liver of a 3':5'-cyclic AMP stimulated kinase for the I form of UDPG glycogen glucosyltransferase. PMID- 4304334 TI - Malate dehydrogenase in leaf peroxisomes. PMID- 4304335 TI - Studies on rat liver ribonucleases. 3. Further studies on heterogeneity of liver lysosomes--intracellular localization of acid ribonuclease and acid phosphatase in rats of various ages. PMID- 4304336 TI - X-ray modification of the catalytic and allosteric functions of fructose-I, 6 diphosphatase. PMID- 4304337 TI - [Influence of ACTH and prolactin injection on gestation in hypohysectomized female Gambusia]. PMID- 4304339 TI - A study of malignant tumour of synovial origin. PMID- 4304338 TI - Choriocarcinoma and related trophoblastic tumors in women. PMID- 4304340 TI - The histogenesis and clinical significance of acidophilic bodies in various liver diseases. PMID- 4304341 TI - Biosynthesis and inactivation of the adrenergic transmitter substance. PMID- 4304343 TI - Physiological aspects of cholinergic and monoaminergic neurones. PMID- 4304342 TI - Spontaneous activity of single neurones in the hypothalamus of rabbits during sleep and waking. AB - 1. A method is described for recording from single cells in the hypothalamus of unanaesthetized freely moving rabbits. Behaviour, bodily movement, skin and brain temperatures and e.e.g. were monitored.2. Patterns of unit firing during slow sleep, paradoxical sleep and waking were studied in several regions of the hypothalamus, thalamus and in the septum.3. Of the 144 cells analysed from waking to slow sleep, fifty-six (39%) decreased mean firing rates, thirty (21%) increased spike discharges and fifty-eight (40%) showed no marked change. Dorsal hypothalamic and massa intermedia thalamic cells fired in brief high frequency clusters during slow sleep with a characteristic ;bimodal' interspike interval histogram. Waking and paradoxical sleep abolished these cluster discharges with a concomitant change to an ;asymmetric' histogram.4. Of the thirty-two cells observed during the three states of waking, slow sleep and paradoxical sleep, a majority (twenty-five or 78%) showed their highest rates of spontaneous discharge during paradoxical sleep. Discharge rates of cells sometimes changed in the course of paradoxical sleep according to the presence or absence of phasic events such as myoclonic motor activity. Two hypothalmic cells were almost totally arrested during paradoxical sleep.5. Analysis of unit firing rates during spontaneous rises in brain temperature during waking and paradoxical sleep revealed that a majority of the neurones (22/24) changed their discharge rates in relation to behaviour rather than to brain temperature. Two cells did appear to respond specifically to the central thermal stimulus.6. Hypothalamic cells do not behave as a homogeneous population in relation to changes in the state of arousal of the rabbit. Spontaneous changes in cell discharge related to sleep-waking behaviour must be considered in any interpretation of hypothalamic unit activity as related to neuroendocrine or autonomic mechanisms. PMID- 4304344 TI - Effects of catecholamines on the cholinergic neuromuscular transmission in fish red muscle. AB - 1. The effects of adrenaline and noradrenaline on neuromuscular transmission and the question of whether these catecholamines act on the presynaptic nerve terminal or on the post-synaptic membrane were investigated using the fin muscles of the silver carp.2. Noradrenaline (10(-8)-10(-6) g/ml.) had no effect on membrane potential or input resistance of the membrane. In contrast, adrenaline (10(-8)-10(-6) g/ml.) hyperpolarized the membrane and increased the input resistance.3. Noradrenaline had no effect on the amplitude of the miniature junction potentials but caused them to become more frequent.4. Adrenaline enhanced the amplitude of the miniature junction potentials and slightly increased their frequency. These effects of adrenaline were partly due to the increased input resistance of the post-synaptic membrane, and probably did not involve the presynaptic terminals.5. Both noradrenaline and adrenaline increased the amplitude and prolonged the falling phase of the excitatory junction potentials (e.j.p.s).6. Noradrenaline enhanced the amplitude and prolonged the duration of the extracellularly recorded excitatory junction current. No such effect was observed with adrenaline.7. Adrenaline but not noradrenaline enhanced the amplitudes of acetylcholine potentials evoked by iontophoretic application of acetylcholine.8. Noradrenaline and adrenaline had no effect on the compound action potentials of the nerve supplying the red muscle, recorded by the sucrose gap method. PMID- 4304345 TI - Adrenocortical insufficiency related to oral contraceptives. PMID- 4304346 TI - [Effect of polymyxin on phytopathogenic bacteria]. PMID- 4304347 TI - [On the microcirculatory activity of angiotensin in normal subjects]. PMID- 4304348 TI - Infection of hamster spleen and thymus with herpes simplex virus in vitro and in vivo. PMID- 4304349 TI - Susceptibility of human lymphoblasts (RPMI 7466) to viral infections in vitro. PMID- 4304350 TI - In vitro stimulation of renin production by epinephrine, norepinephrine, and cyclic AMP. PMID- 4304351 TI - Metabolism of lecithin and virus-induced cell fusion. PMID- 4304352 TI - The effect of interferon on focus formation and yield of murine sarcoma virus in vitro. PMID- 4304353 TI - Glucagon and epinephrine responsive adenyl cyclase activity of regenerating rat liver. PMID- 4304354 TI - Reversal of streptozotocin diabetes with nicotinamide. PMID- 4304355 TI - [The juxtaglomerular cell granule and its significance]. PMID- 4304356 TI - Rapid eye movement sleep deprivation: a central-neural change during wakefulness. AB - Three adult cats were deprived of rapid eye movement sleep for six separate periods of up to 32 days. Animals were allowed normal amouints of sleeping time during which rapid eye movement sleep was interrupted, whenever it occurred, by human observers who continually monitored the animals and their electrocortical activity. Cortical responses evoked by pairs of acoustic clicks were recorded during wakefulness. Recovery functions derived from these data were facilitated during periods of deprivation of rapid eye movement sleep and returned to base line values when animals were allowed normal amounts of this sleep phase. This change was noted repeatedly within, as well as between, subjects. It did not occur during control periods when non-rapid eye movement sleep was interrupted on identical schedules, nor did it occur when the cats were deprived of all sleep for 22 hours a day for 5 days. PMID- 4304357 TI - Polyoma virus gene activity during lytic infection and in transformed animal cells. AB - Randomly labeled RNA's from animal cells either productively infected or transformed by polyoma virus were used to measure virus DNA transcription. During lytic infection, 50 percent of polyoma virus DNA was expressed. In two different polyoma-transformed hamster cell lines, the same 20 percent of the virus genome was transcribed. About 10 percent of polyoma DNA was expressed in the one mouse transformed cell line examined. PMID- 4304358 TI - Endocrine control of adrenal progesterone secretion in the ovariectomized rat. AB - In the ovariectomized rat, the adrenal gland secretes progesterone. Adrenocorticotropin treatment elevates concentrations of this steroid in plasma, and inhibitors of adrenocorticotropin or progesterone biosynthesis lower the concentration. Adrenocorticotropin controls progesterone secretion by the adrenal but not by the ovary. Adrenal progesterone and its mode of control may have important influences on reproductive processes. PMID- 4304359 TI - Fusidic acid: inhibition of factor T2 in reticulocyte protein synthesis. AB - The steroid antibiotic fusidic acid inhibits reticulocyte protein synthesis. This inhibition appears to be due to interference with the activity of the T(2) supernatant fraction, and strengthens the proposition that T(2) is functionally analogous to the G-factor of bacterial protein synthesis, which is also specifically inhibited by this antibiotic. PMID- 4304361 TI - Partial inactivation of angiotensin II by plasmin. PMID- 4304360 TI - Mammary tumor virus antigen: sensitive immunoassay. AB - A rapid, sensitive immuno-assay for mammary tumor virus antigen based on inhibition of passive hemagglutination has been developed. The method permits measurement of this antigen in mouse milk from which the fat has been removed. PMID- 4304362 TI - [On the effect of hyperthermia on respiration and respiratory enzymes]. PMID- 4304363 TI - [Studies on total serum lipids in children. 3. On variations in total serum lipids following drug administration in healthy infants and in various diseases]. PMID- 4304364 TI - Polyneuropathy in childhood. PMID- 4304365 TI - "Retinal anlage" tumors. Melanotic progonoma, melanotic adamantinoma, pigmented epulis, melanotic neuroectodermal tumor of infancy, benign melanotic tumor of infancy. PMID- 4304367 TI - [Apropos of umbilical pathology related to evolutional changes of the umbilical mesenteric duct: 2 original case reports. I. Vascular-stromal residues of the umbilical--mesenteric duct. II. Adenoma from residues of umbilical-mesenteric duct]. PMID- 4304366 TI - Cerebral gigantism. PMID- 4304369 TI - [Contractile response of isolated smooth muscles to repeated stimulations by angiotensin]. PMID- 4304368 TI - Adrenal medullary contribution to the progressive pressor response to angiotensin in the rabbit. PMID- 4304370 TI - [Anorexia nervosa. Case report and endocrinological findings]. PMID- 4304371 TI - [Exhaltation of hydrocyanic acid in cyanide poisoning]. PMID- 4304372 TI - [Experimental studies with cyclic imides. I. Modification of hypophyseal-adrenal axis by thalidomide]. PMID- 4304373 TI - Electron-spin-resonance evidence for enzymic reduction of oxygen to a free radical, the superoxide ion. AB - 1. An electron-spin-resonance signal with g( parallel)2.08 and g( perpendicular)2.00 is observed by the rapid-freezing technique during the oxidation of substrates by molecular oxygen catalysed by xanthine oxidase at pH10. 2. The intensity of this signal is shown to depend on oxygen rather than on enzyme concentration, indicating that it is due to an oxygen free radical and not to the enzyme. 3. The same species is shown to be produced in the reaction at pH10 between hydrogen peroxide and periodate ions. Studies with this system have facilitated comparison of the properties of the oxygen radical with data in the literature on the products of pulse radiolysis of oxygenated water over a wide pH range. 4. It is concluded that the species observed is the superoxide ion, O(2) ( ), and that the stability of this ion is greatly increased in alkaline solution. A mechanism explaining the alkaline stability is proposed. 5. The importance of O(2) (-) in the enzymic reaction is discussed. PMID- 4304374 TI - [Study of an interferon induced by the foot-and-mouth disease virus strain C (Loupoigne) in the testicular cells of the calf]. PMID- 4304376 TI - Effect of an extract of UV-irradiated linolenic acid on azo dye carcinogenesis. PMID- 4304375 TI - [Epizootiology of clostridium infections]. PMID- 4304377 TI - Evidences for a hypocalcemic factor from pituitary gland. PMID- 4304378 TI - Sir Henry H. Dale, O.M., G.B.E., M.D., F.R.C.P., F.R.S. PMID- 4304379 TI - Rapid titration of high concentrations of SV40 virus by immunofluorescence. PMID- 4304380 TI - Chemistry of lipid of the posthemyolytic residue or stroma of erythrocytes. XVI. Occurrence of ceramide pentasaccharide in the membrane of erythrocytes and reticulocytes of rabbit. PMID- 4304381 TI - Water and electrolyte shifts in the presence of two vasoactive substances. PMID- 4304382 TI - Renal function in the European eel (Anguilla anguilla L.): effects of the caudal neurosecretory system, corpuscles of Stannius, neurohypophysial peptides and vasoactive substances. PMID- 4304383 TI - Evidence for thyrocalcitonin binding to protein in plasma. PMID- 4304384 TI - The inactivation of poliovirus in aerosols. PMID- 4304385 TI - Synthesis of natural human angiotensin I. PMID- 4304386 TI - Vertical transmission of murine leukemia virus. PMID- 4304387 TI - Vertical transmission of murine leukemia virus through successive generations. PMID- 4304388 TI - Preliminary report on virus-like particles in a transplantable rat mammary carcinoma. PMID- 4304389 TI - Phorbol ester tumor-promoting agents and membrane stability. PMID- 4304390 TI - A comparative cytologic study of the cultivation of hepatomas of different growth rates. PMID- 4304391 TI - Additional studies of interferon production by human leukemic leukocytes in vitro. PMID- 4304392 TI - Lymphocytosis-promoting factor produced by Bordetella pertussis. Partial purification and characterization. PMID- 4304393 TI - [Reoviruses]. PMID- 4304394 TI - Genetics and cancer. PMID- 4304395 TI - Random coil conformation of polypeptide hormone precursor protein in endocrine cells. PMID- 4304398 TI - Autofluorescence of visual receptors. PMID- 4304397 TI - Free radical reactions modify cellular damage. PMID- 4304396 TI - 220 MHz proton magnetic resonance spectrum of NADH. PMID- 4304399 TI - Control of Marek's disease by the use of inoculated chicken embryo fibroblasts. PMID- 4304400 TI - Increased tyrosine hydroxylase activity after drug-induced alteration of sympathetic transmission. PMID- 4304402 TI - [Syndrome of aspetic meningitis. Etiological study of some cases in the City of Sao Paulo. Clinical and laboratory considerations]. PMID- 4304401 TI - [Prenatal diagnosis of placental insufficiency]. PMID- 4304403 TI - [Isolation of enterobacteriaceae and enteroviruses from normal children and children with acute diarrhea]. PMID- 4304404 TI - [Hypertensive activity in renal venous blood. Results of animal experimental studies]. PMID- 4304405 TI - [Treatment of patent arteriovenous ductus]. PMID- 4304406 TI - The measurement of urinary testosterone glucuronide by competitive protein binding and validation by a double isotope derivative assay. PMID- 4304407 TI - [Considerations on the etiology of facial paralysis. I]. PMID- 4304408 TI - A combined bovine parainfluenza and adenovirus vaccine. PMID- 4304409 TI - [A study of the antiviral and interferonogenic activity of various copolymers of vinylpyrrolidone]. PMID- 4304410 TI - [Myelogenic bone tumors]. PMID- 4304411 TI - [Use of O-nitrophenylbutyrate as source of error in the measurement of the 2-PAM reactivity potential of alkylphosphate-poisoned serum cholinesterase]. PMID- 4304412 TI - [Immuneadherence as an assay for antibodies and antigens. II. Immuneadherence hemadsorption as an assay for cell and specific antigens on culture cells]. PMID- 4304413 TI - [Inapparent virus infections in poultry and their significance with special reference to an agent isolated for the first time. I]. PMID- 4304414 TI - Aspects of oral development in relation to litter size in rats. PMID- 4304415 TI - An ultrastructural and histochemical study of rat atrial myocardium. PMID- 4304416 TI - Fine structure of Leydig cells from an arrhenoblastoma of the ovary. PMID- 4304417 TI - Systemic effects of intestinal revascularization. PMID- 4304418 TI - In vitro culture of spleen cells from a case of Gaucher's disease. PMID- 4304419 TI - Cleveland Clinic Fire Survivorship Study, 1929-1965. PMID- 4304420 TI - Ozone and lipid peroxidation. PMID- 4304421 TI - Comparison of motor and sensory nerve conduction velocity in early uremic polyneuropathy. PMID- 4304422 TI - [Kidney function, electrolyte and carbohydrate metabolism. The works of Gerhard Senft]. PMID- 4304423 TI - The course and prognosis in some types of carcinomatous neuromyopathy. PMID- 4304424 TI - Peripheral neuropathy and myopathy associated with carcinoma of the lung. PMID- 4304425 TI - A comparative study of peripheral nerve conduction in diabetes and non-diabetic chronic occlusive peripheral vascular disease. PMID- 4304427 TI - Enhancement by angiotensin of pressor responses to endogenous noradrenaline in the pithed rat. PMID- 4304426 TI - Sustained complete autonomic blockade. AB - 1. A 3-hr period of complete autonomic blockade was induced in anaesthetized sheep and dogs using a continuous intravenous infusion of trimetaphan camphorsulphonate and atropine. Circulatory, respiratory and metabolic parameters were studied over 24 hr or until the animal died, whichever came first.2. After termination of the blockade all animals remained hypotensive and within a few hours all died in irreversible shock which was not accompanied by any of the otherwise characteristic respiratory or metabolic consequences of circulatory failure.3. Administration of trimetaphan alone for a similar period was innocuous.4. When during complete autonomic blockade a continuous infusion of dopamine or hypertensin was additionally administered mortality rate was halved but all survivors remained hypotensive. PMID- 4304428 TI - Magnetic resonance studies of anaesthetics in cyto-membranes. PMID- 4304429 TI - Blood angiotensin II levels of normal and hypertensive subjects. AB - A specific radioimmunoassay for angiotensin II has shown that its normal concentration in arterial blood is 2.4+/-1.2 (S.D.) mmug./l00 ml.; the venous level is consistently below this value, being usually 50-75% of it. Definite rises in blood angiotensin II levels were found in some patients with hypertension, both essential and secondary to renal disease. Extremely low levels were observed in two anephric women, and in one patient with Conn's syndrome. This radioimmunoassay offers a valuable alternative to renin bioassay in evaluation of the role of the renal pressor system in clinical disorders associated with hypertension and aldosteronism. PMID- 4304430 TI - The treatment of Wilms' tumour with special reference to actinomycin D. PMID- 4304431 TI - Histochemical studies on steroid diabetes of guinea pigs with special reference to Langerhans islets of the pancreas. PMID- 4304432 TI - Adenohypophysial glycogenolysis in relation to ACTH release induced by intrapituitary injection of a purified hypothalamic CRF. PMID- 4304433 TI - [Effect of hypophysectomy and ACTH administration on the development of experimental arteriosclerosis in rats]. PMID- 4304434 TI - Entamoeba histolytica: effect of metal ions, metal binders, therapeutics, antibiotics, and inhibitors on aldolase activity. PMID- 4304435 TI - Cytochrome c oxidase in migrating larvae of Ascaris lumbricoides var. suum. PMID- 4304436 TI - Studies on the mode of action of diphtheria toxin. VII. Toxin-stimulated hydrolysis of nicotinamide adenine dinucleotide in mammalian cell extracts. AB - When diphtheria toxin and NAD are added to soluble fractions containing aminoacyl transfer enzymes isolated from rabbit reticulocytes or from HeLa cells, free nicotinamide is released and, simultaneously, an inactive ADP ribose derivative of transferase II is formed. The reaction is reversible, and in the presence of excess nicotinamide, toxin catalyzes the restoration of aminoacyl transfer activity in intoxicated preparations. In living cultures of HeLa cells, the internal NAD concentration is sufficiently high to account for the rapid conversion, catalyzed by a few toxin molecules located in the cell membrane, of the entire cell content of free transferase II to its inactive ADP ribose derivative. Completely inactive ammonium sulfate fractions containing soluble proteins isolated from cells that have been exposed for several hours to excess toxin, can be reactivated to full aminoacyl transfer activity by addition of nicotinamide together with diphtheria toxin. Transferase II appears to be a highly specific substrate for the toxin-stimulated splitting of NAD and thus far no other protein acceptor for the ADP ribose moiety has been found. PMID- 4304437 TI - Communicability of enteric live adenovirus type 4 vaccine in families. PMID- 4304438 TI - Hereditary epidermolysis bullosa. PMID- 4304439 TI - Inactivated myxovirus vaccines, atypical illness, and delayed hypersensitivity. PMID- 4304440 TI - Some physiochemical properties of Yaba poxvirus deoxyribonucleic acid. AB - Yaba tumor poxvirus deoxyribonucleic acid (DNA) has a density of 1.6905 in CsCl and its T(m) value in 0.015 m citrate in saline is 82.3. The guanine plus cytosine content estimated from these properties was taken to be 32.5 +/- 0.5%, a value 2 to 3% less than for DNA from other poxviruses reported to date. PMID- 4304441 TI - Characteristics of the syrian hamster ribonucleic acid present in cells transformed by polyoma, simian virus 40, or adenovirus 12. AB - Ribonucleic acids of known specific activities were separately prepared from hamster cells transformed by polyoma, simian virus 40 (SV40), and adenovirus 12. When increasing amounts of these labeled ribonucleic acids were added to nitrocellulose filters containing immobilized (14)C-hamster deoxyribonucleic acid (DNA), about 5% of the DNA sites were saturated in each case. An additive saturation-hybridization experiment indicated that a portion of the 5% of the hamster DNA transcribed in SV40-transformed cells was also transcribed in polyoma transformed cells. In addition, a separate region of the hamster genome was also transcribed in polyoma-transformed cells. PMID- 4304442 TI - Isolation of naturally occurring viruses of the murine leukemia virus group in tissue culture. AB - A tissue culture cell system for isolation and identification of members of the murine leukemia virus group (the complement fixation for murine leukemia test) was modified to permit the isolation of naturally occurring virus from leukemic and normal mice. The important factors for increasing the sensitivity of the test were the use of National Institutes of Health (NIH) strain Webster Swiss embryo cell cultures and the selection of rat-immune sera having complement-fixing antibodies to tissue culture antigens of both the Gross and FMR subgroups. In all, 163 strains of mouse leukemia virus, from 11 inbred mouse strains, have been isolated. Representative virus isolates were shown to possess the properties of the murine leukemia virus group; i.e., they were chloroform-sensitive, noncytopathic agents which replicated in mouse embryo tissue culture and produced group-reactive, complement-fixing antigen and budding C-type particles visible by electron microscopy. These viruses could serve as helpers in the rescue of Moloney sarcoma virus genome from non-producer hamster sarcoma cells, yielding pseudotypes. All of the 19 field isolates tested were neutralized by Gross passage A antiserum but not by potent antisera to the Moloney, Rauscher, and Friend strains. Virus was recovered regularly from embryos and from the plasma and spleen of adult mice of high leukemic strains. In low leukemic mouse strains, different patterns of virus detection were observed. In C3H/He mice, virus was occasionally present in embryos and was found in 40% of adult spleens. BALB/c mice were virus-negative as fetuses or weanlings, but spleens of more than half of the mice over 6 months of age yielded virus. NIH mice have never yielded virus. In reciprocal matings between AKR and BALB/c mice, virus recovery from embryos was maternally determined. The development of tissue culture isolation procedures made possible for the first time the application of classical infectious disease methods to the study of the natural history of murine leukemia virus infection. PMID- 4304443 TI - Multiple group-specific antigen components of avian tumor viruses detected with chicken and hamster sera. AB - Multiple group-specific (gs) components of the avian leukosis-sarcoma viruses were detected by immunodiffusion (Ouchterlony) tests with sera from hamsters bearing tumors induced by sarcoma viruses and with sera from adult chickens immunized with avian sarcoma or leukosis viruses. Immune hamster sera detected up to four components, whereas chicken sera detected at least one. The hamster and chicken sera identified a similar antigen, as indicated by reactions of identity. Relatively few chicken sera containing neutralizing antibody to avian sarcoma or leukosis viruses reacted in immunodiffusion with the gs antigen. The gs components were released from the virion by various means of disruption, including freezing and thawing. Tests with tissues from normal chickens and from chickens with Marek's disease failed to demonstrate any reactions with hamster or chicken gs antiserum. PMID- 4304444 TI - Origin of the thymidine kinase induced by polyoma virus in productively infected cells. AB - Cells of the 3T3 mouse line efficiently supported the multiplication of polyoma virus, and the infectious process was accompanied by a marked increase in thymidine kinase (TK) activity. Two lines of 5-bromodeoxyuridine-resistant 3T3 cells have been isolated. As expected, these cells incorporated practically no exogenous thymidine into their deoxyribonucleic acid (DNA) and contained negligible TK activity. Like the parental 3T3 cells, TK(-) lines were susceptible to productive infection by polyoma virus, but infection did not lead to an increase in TK activity. Since kinase activity did appear after infection with another virus (vaccinia) known to contain the gene(s) for that enzyme, it is concluded that TK is not one of the gene products of polyoma virus. As induction of cellular DNA synthesis by polyoma virus occurs normally when the TK(-) cells are infected in the stationary phase, TK cannot play a role in the determination of this phenomenon. PMID- 4304445 TI - Reversion in polyoma-transformed cells: retransformation, induced antigens and tumorigenicity. AB - We studied the properties of two morphologically reverted cell clones isolated as chromosomal segregants from a "hybrid" clone of BHK 21/13 hamster fibroblasts, transformed with polyoma virus. Both clones were less tumorigenic than control transformed cells. They contained no detectable polyoma-specific complement fixing antigen. Induced transplantation antigen also appeared to be lost or reduced. Both clones could be retransformed with polyoma virus, suggesting that their reversion is due to the loss of viral genes from the transformed cell. PMID- 4304446 TI - Markers of rubella virus strains in RK13 cell culture. AB - When tested on RK(13) cell cultures, strains of rubella virus could be differentiated by their ability to form small or large plaques. Large plaques were produced by the HPV-77 and Cendehill strains, and also by a laboratory stock strain (West Point), after only 14 passages in RK(13) culture. Five wild-type rubella viruses, isolated and passaged only a few times in African green monkey kidney tissue culture, grew well in RK(13) cell culture, but they were sensitive to agar inhibitors and, therefore, formed small plaques. On the other hand, RA27/3, an attenuated strain grown in WI-38 human fibroblast cells, developed low titers in RK(13) cells and also produced small plaques. We concluded that the morphological differences between small-plaque and large-plaque viruses depended on their sensitivity to agar inhibitors and on the pH of the medium during plaque formation. PMID- 4304447 TI - Filamentous structures of type 2 Herpesvirus hominis infection of the chorioallantoic membrane. AB - In view of recent recognition of the existence of two Herpesvirus hominis (HVH) types with antigenic and biological differences, an electron microscopic study was undertaken of pocks produced on the choriallantoic membrane of embryonated eggs after infection with type 1 and type 2 HVH strains. Besides the typical morphological features of herpesvirus infection noted by several investigators, it was observed that type 2 HVH also produced microtubules measuring approximately 19 nm in both nucleus and cytoplasm. Although the nature of these filamentous structures is still unclear, consideration is given in this paper to the possibility that they may represent viral structural subunits, aberrant forms or neoantigens. PMID- 4304448 TI - New nuclear ribonucleic acid in cell cultures infected with polyoma virus. PMID- 4304449 TI - [The efficacy of complex therapy of patients with tuberculosis and diabetes mellitus]. PMID- 4304450 TI - A review of the recent research on sleep and dreaming. PMID- 4304451 TI - [Restoration of the function of the hand in radial nerve paralysis]. PMID- 4304453 TI - Myxedema and ataxia. PMID- 4304452 TI - Inherited predisposition to generalized amyloidosis. Clinical and pathological study of a family with neuropathy, nephropathy, and peptic ulcer. PMID- 4304454 TI - Unilateral numbness of the face and the basal cisternogram. PMID- 4304455 TI - [Effect of sodium dipropylacetate on certain varieties of epileptogenic encephalopathies in infants]. PMID- 4304456 TI - Fauna of Catal Huyuk: evidence for early cattle domestication in Anatolia. AB - Analysis of the remains of cattle from Catal Huyuk indicates that cattle were domesticated in Anatolia by 5800 B.C., and strongly suggests that they were probably domestic at least 500 years earlier. This is the earliest known evidence for the domestication of cattle in the Near East. PMID- 4304458 TI - [Neck-arm syndrome]. PMID- 4304457 TI - Infections and pregnancy: a review. PMID- 4304459 TI - [Paget's disease]. PMID- 4304460 TI - Pneumonia in gnotobiotic pigs produced by simultaneous inoculation of a swine adenovirus and mycoplasma hyopneumoniae. PMID- 4304461 TI - [Morphological changes in the diencephalon and the telencephalon after disturbance of the regulatory circuit adenohypophysis-adrenal cortex. I. Results in guinea pigs after administration of natural and synthetic ACTH]. PMID- 4304462 TI - [Attempts of demonstration of viruses in the vaginal]. PMID- 4304463 TI - Evaluation of laboratory problems of glassblowers working fused quartz. PMID- 4304464 TI - Treatment of herpes simplex keratitis. A review. PMID- 4304465 TI - Treatment of uveitis with methotrexate. PMID- 4304466 TI - Surgical management of solid tumors in childhood. PMID- 4304467 TI - Response to radiation therapy of osseous lesions detected on radioisotope bone scans. PMID- 4304468 TI - Angiographic manifestations of Wilms' tumor. An observation of six cases. PMID- 4304469 TI - [Anatomo-clinical remarks on a case of chemodectoma of the tympanic glomus]. PMID- 4304470 TI - [On the histogenesis of hepatic carcinoma. Apropos of specific fetoproteins]. PMID- 4304471 TI - [Prognosis of sarcoma of the uterine body]. PMID- 4304472 TI - [Syn-polydactyly in an ox]. PMID- 4304473 TI - The perception-hallucination continuum. (A re-examination). PMID- 4304474 TI - [Study of discharge synchronization of human motor neurons based on cross number correlation analysis of interferential electromyograms]. PMID- 4304475 TI - [Evoked potentials in the posterior ventro-lateral thalamic nucleus in response to stimulation of mesenteric nerves and gastro-intestinal receptors]. PMID- 4304476 TI - [Analysis of hypothalamic influences on mono- and polysynaptic potentials of the spinal cord and on the electrocorticogram]. PMID- 4304477 TI - [Origin of trace depression of a sympathetic ganglion]. PMID- 4304478 TI - Study of typability of staphylococci in relation to their resistance to antibiotics. PMID- 4304479 TI - Melanoameloblastoma: report of case. PMID- 4304480 TI - [Results of hormone treatment in propulsive-petit mal-epilepsy]. PMID- 4304481 TI - [Canditoxin, a new toxic substance isolated from a strain of Candida albicans. 6. Kinds of intracellular phosphatases and their fluctuations during the growth of the toxin-producing organism]. PMID- 4304482 TI - [On the histochemical study of larval and adult stages of Alveococcus multilocularis (Leuckart, 1863) Abuladse, 1959]. PMID- 4304483 TI - [Autohistioradiographic research on the localization in the central nervous system of poliovirus, type 3, attenuated with the Sabin method and labeled with I 131]. PMID- 4304484 TI - Unexpected high incidence of tumours in thymectomized mice treated with anti lymphocytic globulin and Mycobacterium leprae. PMID- 4304485 TI - Induction of liver and lung tumours in mice by 6-aminochrysene administered during the 1st 3 days of life. PMID- 4304486 TI - Pressor response to angiotensins I and II and renin in rats treated with carbon tetrachloride. PMID- 4304487 TI - Solubilization and some properties of the erythrocyte receptor for adenovirus type 7 haemagglutinin. PMID- 4304489 TI - [Primary carcinoma of the liver in children]. PMID- 4304488 TI - [Intracranial hypertension due to septal cyst blocking Monro's foramen]. PMID- 4304490 TI - [On the differential diagnosis of osteoglastic metastases and chylothorax]. PMID- 4304491 TI - [Neurologic complications of cavum cancers. Study of 160 personal cases of malignant cavum tumors]. PMID- 4304492 TI - [Polygraphic study of intermediate phases of sleep of mental patients compared with eye movement phases]. PMID- 4304493 TI - [On malignant synoviomas with epithelium-like structures]. PMID- 4304494 TI - [Characteristic of Wilm's tumor cell line in vitro]. PMID- 4304495 TI - [Artificial induction of transplant types of viral antigens during chemical carcinogenesis]. PMID- 4304496 TI - [Oncogenic properties of polyoma virus strain 13-Moscow]. PMID- 4304497 TI - [On the significance of Bursa Fabricii in tumor induction in chickens by Rous sarcoma virus]. PMID- 4304498 TI - [Remote results of the surgical treatment of ovarian theca-cell tumors]. PMID- 4304499 TI - [On the combined treatment of "mixed" tumors of the parotid gland]. PMID- 4304500 TI - [On the treatment of parapsoriasis and mycosis fungoides (results of the clinical climate therapy on the North Sea)]. PMID- 4304501 TI - [Studies on the effect of various hormones and vitamins on the metabolism of the sulfated mucopolysaccharides of the connective tissue]. PMID- 4304502 TI - [Examination of the dynamic behavior of 17-ketosteroids and 17 hydroxycorticosteroids in women with gonadal dysgenesis]. PMID- 4304503 TI - [Detection of serum antibodies neutralizing Reoviruses in a sample of the population of Rome]. PMID- 4304504 TI - [Detection of serum antibodies against Reoviruses, Adenoviruses and Coxiella burneti in a group of inhabitants of Riyad (Saudi Arabia)]. PMID- 4304505 TI - [Detection of hemagglutination-inhibiting antibodies against some respiratory Myxoviruses in a group of individuals of Swat (northwestern Pakistan)]. PMID- 4304506 TI - [Detection of serum antibodies neutralizing Reoviruses in a sample of the population of Accra (Ghana)]. PMID- 4304507 TI - [Morphological changes in the internal organs caused by the lecithinase-C of Cl. welchii, type A]. PMID- 4304508 TI - [Cytomegaly, cirrhosis and cancer of the pancreas in a patient with gummatous visceral syphilis]. PMID- 4304509 TI - Triglyceride synthesis by the small-intestinal epithelium of the pig, sheep and chicken. AB - 1. A comparative study was made of triglyceride synthesis by the intestinal epithelium of pigs, sheep and chickens. In pig and chicken tissue both the glycerol 3-phosphate and the monoglyceride pathway of triglyceride synthesis were operative, but the former pathway predominated in sheep tissue. 2. The fatty acid specificity of the glycerol 3-phosphate pathway was studied in pig and sheep total-homogenate preparations. Maximum incorporation was obtained with myristic acid and palmitic acid under optimum conditions for each fatty acid. Lauric acid, myristic acid, oleic acid, linoleic acid and linolenic acid were inhibitory at concentrations above their optimum, but octanoic acid, decanoic acid, palmitic acid and stearic acid did not show this effect. 3. Subcellular fractionation located the glycerol 3-phosphate and monoglyceride pathways of triglyceride synthesis in the microsomes in all instances. Phosphatidate phosphohydrolase was associated with both the microsomes and the particle-free supernatant. 4. Glycerol 1-mono-oleate was incorporated into triglycerides to a greater extent than glycerol 1-mono-palmitate or glycerol 1-monostearate by microsomal preparations from pig and chicken. 5. A lipase specific for monoglycerides was detected in the particle-free supernatant of all the species examined. PMID- 4304510 TI - The osmotic stability of lysosomes from adult and foetal guinea-pig liver tissue. AB - 1. Lysosome-rich fractions were obtained from foetal liver tissues as early as 35 days uterine age. Foetal lysosomes showed the same ;structure-linked latency' and acid hydrolytic potentiality characteristic of their adult counterparts. 2. The osmotic stability of lysosome-rich fraction from foetal guinea-pig liver tissue was greater than that of the corresponding adult lysosome fractions, p nitrophenyl-phosphatase being used as marker enzyme. 3. The observation was confirmed by using beta-glycerophosphatase and phenolphthalein beta-glucuronidase as alternative marker enzymes. p-Nitrophenyl phosphate and beta-glycerophosphate appear to act as substrates for the same enzyme. 4. By using p nitrophenylphosphatase activity measurements it was shown that the osmotic stability of foetal lysosomal fractions decreased with increasing foetal age, but at no time achieved the degree of osmotic instability characteristic of adult lysosomal fractions. 5. The correlation of these findings with the intracellular environment of lysosomes is discussed. PMID- 4304511 TI - Incorporation of [32P]orthophosphate into brain-slice phospholipids and their precursors. Effects of electrical stimulation. AB - 1. The incorporation of [(32)P]phosphate into phospholipids was measured in slices cut from the pial surface of guinea-pig cerebral cortex; incorporation into the phosphorus of some water-soluble precursors of phospholipid was measured under similar conditions. 2. Slices subjected to overall electrical stimulation at a frequency of 5pulses/sec. differed from control slices in their pattern of phospholipid labelling. After 1hr. of stimulation, incorporation of [(32)P]phosphate into phosphatidylcholine, ethanolamine phospholipid and cardiolipin was respectively 54, 55 and 58% of the control value, and that into phosphatidylinositol was 186% of control. Phosphatidic acid labelling tended to increase with electrical stimulation, but the statistical significance of this change was marginal. Labelling of phosphatidylglycerol and di- and tri phosphoinositides was not affected significantly by electrical stimulation. 3. Electrical stimulation of the tissue altered the specific radioactivities of water-soluble precursors of phospholipid. 4. The turnover rates of the phosphate groups of phospholipids were estimated approximately from the specific radioactivities of phospholipids and their precursors. Phosphatidylinositol (and its lipid-soluble precursors) showed the largest change in turnover rate in response to electrical stimulation of the tissue; the turnover rates of other lipids were also affected. Changes in the specific radioactivity of phospholipids did not correspond to changes in turnover in these experiments. PMID- 4304512 TI - Phospholipid exchange reactions within the liver cell. AB - 1. Isolated rat liver mitochondria do not synthesize labelled phosphatidylcholine from CDP-[(14)C]choline or any phospholipid other than phosphatidic acid from [(32)P]phosphate. The minimal labelling of phosphatidylcholine and other phosphoglycerides can be attributed to microsomal contamination. However, when mitochondria and microsomes are incubated together with [(32)P]phosphate, the phosphatidylcholine, phosphatidylinositol and phosphatidylethanolamine of the reisolated mitochondria become labelled, suggesting a transfer of phospholipids between the two fractions. 2. When liver microsomes or mitochondria containing labelled phosphatidylcholine are independently incubated with the opposite un labelled fraction, there is a substantial and rapid exchange of the phospholipid between the two membranes. Exchange of phosphatidylinositol also occurs rapidly, whereas phosphatidylethanolamine and phosphatidic acid exchange only slowly. There is no corresponding transfer of marker enzymes. The transfer of phosphatidylcholine does not occur at 0 degrees , and there is no requirement for added substrate, ATP or Mg(2+), but the omission of a heat-labile supernatant fraction markedly decreases the exchange. 3. After intravenous injection of [(32)P]phosphate, short-period labelling experiments of the individual phospholipids of rat liver microsomes and mitochondria in vivo give no evidence for a similar exchange process. However, the incubation of isolated microsomes and mitochondria with [(32)P]phosphate also fails on reisolation of the fractions to demonstrate a precursor-product relationship between the individual phospholipids of the two membranes. 4. The intraperitoneal injection of [(32)P]phosphate results in a far greater proportion of the dose entering the liver than does intravenous administration. After intraperitoneal administration of [(32)P]phosphate the specific radioactivities of the individual phospholipids are in the order microsomes > outer mitochondrial membrane > inner mitochondrial membrane. 5. The incorporation of (32)P into cardiolipin is very slow both in vivo and in vitro. After labelling in vivo the radioactivity in the cardiolipin persists compared with that of the other phospholipids, whose specific radioactivities in the microsomes and mitochondrial fragments decay at a similar rate to that of the acid-soluble phosphate pool. 6. The possibility of phospholipid exchange processes occurring in the liver cell in vivo is discussed, and it is suggested that only a small but highly labelled part of the endoplasmic reticulum lipoprotein pool is involved in the transfer. PMID- 4304513 TI - [Role of catecholamines concerned in adrenocortical hormone metabolism]. PMID- 4304514 TI - [Clinical study on effect of simultaneous use of xylitol in the prevention of adrenal cortical hypofunction in corticoid therapy]. PMID- 4304515 TI - [Personal experience with infusion cholangiography]. PMID- 4304516 TI - [Neurophysiological characteristics of the cortex isolated from nervous subcortical influences]. PMID- 4304517 TI - [The action of calcium and magnesium on dendrite potentials]. PMID- 4304518 TI - [Thermal influence on excitation summation in the extensor reflex center]. PMID- 4304519 TI - [Postsynaptic neuron potentials of the motor cortical area in awake rabbits]. PMID- 4304520 TI - [Cerebellar influence on intermediate spinal neurons in precollicular cats]. PMID- 4304521 TI - [Study of the interaction of interoceptive and somatic reflex spinal centers]. PMID- 4304522 TI - [Effect of prolonged stimulation of the posterior spinal roots on anterior root potentials in listenon treated frogs]. PMID- 4304523 TI - [On the role of posterior root depolarization in inhibition of monosynaptic flexor reflexes by somatic afferent impulses]. PMID- 4304524 TI - [Functional exploration of the adrenal cortex in basal and dynamic conditions in hypercorticism of the Cushing type]. PMID- 4304525 TI - [Cortisolemic response after administration of synthetic LVP and ACTH in a group of subjects pretreated with dexamethasone]. PMID- 4304526 TI - [Aspects of hypophyseal and adrenocortical function in acromegaly]. PMID- 4304527 TI - [Clinical studies on the stimulation and suppression of the pituitary adrenocortical system. I. Studies on the adrenocortical-stimulating effects of synthetic beta-1-24 ACTH preparations]. PMID- 4304528 TI - [Clinical studies on the stimulation and suppression of the pituitary adrenocortical system. II. Studies on the pituitary-adrenocortical suppression test]. PMID- 4304529 TI - [Clinical studies on the stimulation and suppression of the pituitary adrenocortical system. 3. Studies on the pituitary adrenocortical suppression after long-term glucocorticoid treatment]. PMID- 4304530 TI - [Experimental studies on the ACTH secretion mechanism]. PMID- 4304531 TI - [Clinical observations on plasma growth hormone (HGH) levels]. PMID- 4304532 TI - Bacteremic shock due to gram-negative bacilli. Some concepts of pathogenesis and management based on recent developments. PMID- 4304533 TI - [Pathogenesis of renal hypertension]. PMID- 4304534 TI - [Studies on thin-layer chromatography of compounds having a chelating ability. IX. Relation between the adsorptivity on silica gel and chelating ability]. PMID- 4304535 TI - Comparison of high-pressure oxygen and oxygen-carbon dioxide mixtures in treatment of Clostridium perfringens infection in mice. PMID- 4304536 TI - [Studies on the mechanism of action of diphtheria toxin]. PMID- 4304537 TI - [Secondary lung cancer presenting a diffuse shadow in the lung]. PMID- 4304538 TI - [Case of thoracocolic fistula]. PMID- 4304539 TI - [Case of primary lung cancer in young children]. PMID- 4304540 TI - [Comparative study of primary liver cancer in Japan and Taiwan]. PMID- 4304541 TI - [Autopsy case of subacute hepatitis]. PMID- 4304542 TI - [Perforating duodenal ulcer simulating Japanese encephalitis--acute gastric dilatation and feasibility of parenteral infusion]. PMID- 4304543 TI - [The renin, angiotensin and aldosterone system in secondary hypertension]. PMID- 4304544 TI - [Resection of the trachea in intra-tracheal tumors using cardiopulmonary bypass]. PMID- 4304545 TI - Immunization against adenovirus infections. PMID- 4304546 TI - [Fatal infection with adenovirus type 7. Some immunological aspects]. PMID- 4304547 TI - [Gene structure of influenza viruses]. PMID- 4304548 TI - [Parainfluenza and related diseases]. PMID- 4304549 TI - [Oxygenase]. PMID- 4304550 TI - [Host cell changes caused by animal virus infection, with special reference to electron microscopic morphology]. PMID- 4304551 TI - [Membrane-bound hemoproteins in anaerobically grown yeast cells]. PMID- 4304552 TI - [Histochemical study of brain enzymes]. PMID- 4304553 TI - [New possibilities in venous hepatography; spleno-portal hepatography by means of oil contrast]. PMID- 4304554 TI - [Serio-angiographic study of the morpho-dynamic aspects of various expansive intracranial processes]. PMID- 4304555 TI - [Significance of the combined use of radiosensitizing agents on radiotherapy of malignant encephaloma]. PMID- 4304556 TI - [Experiences with abdominal aortography in children]. PMID- 4304557 TI - [Situs inversus totalis in 2 sisters with one case complicated by stomach cancer]. PMID- 4304558 TI - [Enzymatic character of metaplasia of intestinal epithelium in chronic gastritis]. PMID- 4304559 TI - Thyrocalcitonin: ultracentrifugation in gradients of sucrose. AB - Analysis of thyrocalcitonin, by density-gradient ultracentrifugation at high speed, showed that its molecular weight (5000 to 6000) is considerably less than was heretofore recognized. PMID- 4304560 TI - Release of coordinated behavior in crayfish by single central neurons. AB - By stimulating and recording from the same interneuron at two separate points, we have shown that coordinated output to the postural abdominal muscles of crayfish can be produced by electrical stimulation of a single cell. Several central neurons can individually initiate one type of movement(for example, flexion),each producing a unique abdominal geometry. PMID- 4304561 TI - [Autopsy case of an aged person dying of obstructive jaundice during the treatment of rectal cancer--triple neoplasms of the digestive system]. PMID- 4304562 TI - [Experimental research on the stimulation viral antibody formation under the influence of thymus extracts. II. The kinetics of adenoviral antibodies in guinea pigs]. PMID- 4304563 TI - [Data on some viral enzymes]. PMID- 4304564 TI - [Large benign tumors of the breast (fibroadenoma intracanaliculare phyllodes)]. PMID- 4304565 TI - [The use of antibiotics in surgical practice]. PMID- 4304566 TI - Some aspects of the interaction between polyoma virus and cell DNA. PMID- 4304567 TI - Adenoviruses: the nature of the virion and of controlling factors in productive or abortive infection and tumorigenesis. PMID- 4304568 TI - Distinguishing features of well differentiated mucinous adenocarcinoma of the rectum and colitis cystica profunda. PMID- 4304569 TI - Seasonal variation in adenosine triphosphate and nicotinamide adenosine dinucleotide in normal term placenta. PMID- 4304570 TI - Method for testing virus stocks for viral contaminants. AB - A practical method for testing the purity of virus stocks has been developed and applied to reference stocks of enteroviruses. The method requires the use of a reference antiserum that is substantially free from heterotypic antibody. When selected dilutions of this antiserum are reacted with high concentrations of virus, virus intentionally allowed to escape neutralization is recovered and then identified. A contaminating virus present as a minor component of the population has a far greater probability of being revealed under the conditions of this "breakthrough" test than under the commonly used virus identity tests which customarily employ approximately 100 TCD(50) of virus and, therefore, only identify the major component of the virus population. The breakthrough test described has been used for tests of 104 reference stocks of all the enteroviruses that propagate in monkey kidney cells and human amnion cells. Although all the materials had been previously tested and approved by the commonly employed virus identity test, the breakthrough test in two instances revealed contaminating heterotypic enteroviruses present at a very low titer in the stocks. Without resorting to the stringent, elaborate, and expensive tests for absolute purity, such as those that are required to assure safety of vaccines, the use of the breakthrough test described provides reasonable assurance of purity for stock viruses to be employed as diagnostic reagents or for general laboratory research purposes where a multiplicity of viral agents and antisera are required. PMID- 4304571 TI - Enhancement of the infectivity of rhinovirus ribonucleic acid by diethylaminoethyl dextran. PMID- 4304572 TI - Inactivation of poliovirus type 1 by the Kelly-Purdy ultraviolet seawater treatment unit. AB - Three experiments were conducted to determine the effect of ultraviolet (UV) radiation on poliovirus-contaminated seawater. In two of the experiments, the effectiveness of the Kelly-Purdy UV Seawater Treatment Unit to inactivate poliovirus type 1 (T(1)) suspended in continuously flowing seawater was determined. In experiment 1, the observed survival ratio of poliovirus T(1) was 2.3 x 10(-4) (99.98% reduction) in 15.7 sec. No virus was detected (<0.2 plaque forming unit/ml) in 20.6 seconds. The calculated half-life value was 1.29 sec. In experiment 2, the observed survival ratio of poliovirus T(1) was 5.9 x 10(-4) (99.94% reduction) in 11.7 sec. No virus was detected in 15.7 sec. The calculated half-life value was 1.37 sec. In experiment 3, a laboratory-controlled UV experiment designed to closely simulate the geometry of the continuously flowing seawater system, the observed survival ratios of poliovirus T(1) were 9.7 x 10( 3) (99.03% reduction) and 3.6 x 10(-4) (99.96% reduction) in 15 and 30 sec, respectively; the calculated half-life value was 2.38 sec. A statistically significant difference was found between the inactivation rates of poliovirus T(1) in the two test systems. This rate difference was attributed primarily to UV dosage and stirring effects. The data indicated that UV radiation effectively inactivated poliovirus T(1) in flowing seawater. These results validate the efficacy of the Kelly-Purdy UV Seawater Treatment Unit for use in commercial depuration systems. PMID- 4304573 TI - Virucidal effect of transient electric arcs in aqueous systems. AB - Bacterial and animal viruses were inactivated by high voltage electrical discharges in water. The sensitivity of phages to the immediate component of this effect was correlated to the sensitivity to ultraviolet radiation. Transient electrical arcs in weak electrolytes also generated chemical compounds which were virucidal against phages T3, T5, and varphiX174 but were only slightly virucidal against phages T2 and T4. PMID- 4304574 TI - Inhibition of respiration in submitochondrial particles by N,N' dicyclohexylcarbodiimide: the effect of sodium, potassium, and antibiotics which alter membrane permeability. PMID- 4304575 TI - The enzymic deacylation of esterified mono- and di-saccharides. I. The isolation and purification of an esterase from wheat germ lipase. PMID- 4304576 TI - Physical and chemical studies of Mengo virus variants. II. Chromatographic behavior and chemical composition. PMID- 4304577 TI - Phosphonolipids. XIX. Synthesis of a naturally occurring ceramide aminoethylphosphonate and its enantiomer. PMID- 4304578 TI - Phospholipid metabolism in the molluscs. I. Distribution of phospholipids in the water snail Lymnaea stagnalis. PMID- 4304579 TI - Pleomorphic adenoma, "mixed tumor," minor salivary gland of the palate. Case report. PMID- 4304580 TI - Granular-cell myoblastoma--an unusual rectal neoplasm. Report of a case. PMID- 4304581 TI - Acute renal vein hypertension: oliguria, hormone infusion, and volume expansion. PMID- 4304582 TI - [Anesthesia, surgery and adrenocortical function. 1. Preoperative evaluation of adrenocortical function with a new synthetic beta 1-24 ACTH]. PMID- 4304584 TI - External power and recent concepts in control of limb prostheses. PMID- 4304583 TI - The differential effect of anesthetics on muscle relaxation. PMID- 4304585 TI - Correction concerning electron paramagnetic resonance in human bone mineral. PMID- 4304586 TI - Metabolism of coumarin in man. PMID- 4304587 TI - Induction of sexual excitement by the action of adrenocorticotrophic hormone in brain. PMID- 4304588 TI - Antigenic and biologic differences in herpesvirus hominis. PMID- 4304589 TI - Congenital rubella: the significance of virus persistence. PMID- 4304591 TI - The evaluation of antiviral drugs in volunteers. PMID- 4304590 TI - Interference in human viral infections: present status and prospects for the future. PMID- 4304592 TI - Laboratory aids to the control of smallpox in countries where the disease is not endemic. PMID- 4304593 TI - Multiplicity reactivation of animal viruses. PMID- 4304594 TI - Chemodectoma of the anterior mediastinum. Report of a case of probable aortic body origin with arteriographic findings. PMID- 4304595 TI - Force, shortening, and work in muscular contraction: relative contributions to overall energy utilization. AB - The amounts of energy used during muscular contraction under different loads have been compared by measurement of the total amount of disturbance of the concentration of reduced nicotinamide-adenine dinucleotide during the period of oxidative recovery. The results are in quantitative agreement with the concept that three parameters determine the energy utilization: namely the time-integral of the force development, the time-integral of the shortening process, and the mechanical work. PMID- 4304596 TI - Cytochromes: chemical and structural aspects. PMID- 4304597 TI - Phenotype: postnatal development. PMID- 4304598 TI - [Problems of physiopathology and diagnosis in Addison's disease]. PMID- 4304599 TI - [Experimental concogenesis of the adrenal cortex. Cytopathology of some adrenal cortex tumors experimentally induced in Wistar white rats]. PMID- 4304600 TI - [Action of corticotropin and cortisone on the testicle of the white rat]. PMID- 4304601 TI - Chemotherapy and surgery in the treatment of gestational trophoblastic neoplasms. PMID- 4304602 TI - [Anomalies of the upper extremity]. PMID- 4304603 TI - Long time survivals of patients with cancer of the eye and surrounding structures treated with radiation therapy. PMID- 4304604 TI - Removal of AMP from NADH solutions. PMID- 4304605 TI - Application of glass fiber chromatography for separation of C19 steroids. PMID- 4304606 TI - Studies of hypertension and carbohydrate intolerance associated with Wilms tumor. PMID- 4304607 TI - [Abrikosov tumor of the larynx]. PMID- 4304608 TI - [Study of the polyadenylic acid and polyuridylic acid complexes]. PMID- 4304610 TI - [Structural proteins of the Rous sarcoma virus (Schmidt-Ruppin strain). Electrophoretic study on polyacrylamide gel]. PMID- 4304609 TI - [Interaction of pyruvate and glutamate oxidation in swine heart mitochondria]. PMID- 4304611 TI - [On a strain of Poliovirus requiring semicarbazide]. PMID- 4304612 TI - Focal nodular hyperplasia of the liver: the solitary cirrhotic liver nodule. PMID- 4304613 TI - [The Miguel F. Jimenez lecture. Structural biochemical bases involving the transmission of nerve impulses]. PMID- 4304614 TI - A strategy for discharging long-term patients. PMID- 4304615 TI - Ascochlorin, a new antibiotic, found by the paper-disc agar-diffusion method. I. Isolation, biological and chemical properties of ascochlorin. (Studies on antiviral and antitumor antibiotics. I). PMID- 4304616 TI - New antiviral antibiotics; xanthocillin X mono- and dimethylether, and methoxy xanthocillin X dimethylether. I. Isolation and characterization. (Studies on antiviral and antitumor antibiotics. V). PMID- 4304617 TI - Effect of selected antibiotics and other inhibitors on competence development in Haemophilus influenzae. PMID- 4304618 TI - [Electron microscopic study of the synovial cells and leukocytes in the synovial fluid form a pseudogout syndrome]. PMID- 4304619 TI - Cerebellar glioblastomas. PMID- 4304620 TI - Effects of conditioning afferent volleys on variability of monosynaptic responses of extensor motoneurons. PMID- 4304621 TI - Effect of muscle and cutaneous afferent nerve volleys on excitability fluctuations of Ia terminals. PMID- 4304622 TI - Electrical activity in cat olfactory cortex produced by synchronous orthodromic volleys. PMID- 4304623 TI - Synaptic organization of cat olfactory cortex as revealed by intracellular recording. PMID- 4304624 TI - Hyperpolarizing influence of trigeminal nucleus caudalis on primary afferent preterminals in trigeminal nucleus oralis. PMID- 4304625 TI - Responsiveness of thalamic and cortical motor relays during arousal and various stages of sleep. PMID- 4304626 TI - [Extramammary Paget's disease, with special reference to the pathology of the initial stage]. PMID- 4304627 TI - Enzyme activities in isolated glomeruli of the rat with renal hypertension. PMID- 4304628 TI - The effect of mercuric chloride, of bilateral ureteral ligation and of bilateral nephrectomy on plasma renin substrate concentration in rats. PMID- 4304629 TI - [Follow-up study of pulmonary tuberculosis patients returned to work through the aftercare institution in certain iron works]. PMID- 4304630 TI - [The activity of leukocyte phosphatase in inflammatory diseases]. PMID- 4304631 TI - Plaque formation by herpes simplex viruses in GMK (established grivet monkey kidney) cells. PMID- 4304632 TI - Neurotransmitter quantum released from sympathetic nerves in cat's skeletal muscle. PMID- 4304633 TI - [Differential diagnosis of the Bartter syndrome]. PMID- 4304634 TI - Rapid corticotropin test with 1-24 peptide. PMID- 4304635 TI - Carbohydrate metabolism of choriocarcinoma in continuous tissue culture. PMID- 4304636 TI - [Clinical and genetic contribution to the orofacialdigital syndrome]. PMID- 4304637 TI - Sleep, dreaming and drugs. PMID- 4304638 TI - Controversies in the treatment of rheumatoid arthritis. PMID- 4304639 TI - Toxic chemicals and peripheral neuropathy: clinical and epidemiological features. PMID- 4304640 TI - Toxic chemicals and peripheral neuropathy: experimental studies. PMID- 4304641 TI - Toxic chemicals and peripheral neuropathy. PMID- 4304642 TI - Toxic chemicals and peripheral neuropathy. PMID- 4304643 TI - Toxic chemicals and peripheral neuropathy. PMID- 4304644 TI - [Adrenocortical reactivity in neuropsychiatric disorders with special reference to findings of the EEG and PEG]. PMID- 4304645 TI - [On acute hemorrhagic leukoencophalitis--(Hurst). Autopsy case occuring in the course of scleroderma with pathological changes in the peripheral nerves]. PMID- 4304646 TI - [Development of phosphatides during differentiation of crystalline lens cells]. PMID- 4304647 TI - [On the comparative metabolism of bovine olfactory and respiratory mucous membranes. I. Energetics]. PMID- 4304648 TI - [A method for the detection of peptides separated by column chromatography: application to the analysis of collagen hydrolysates]. PMID- 4304649 TI - A system of secondary prevention in a psychiatric aftercare clinic of a general hospital. PMID- 4304650 TI - Dynamics and significance of cerebral protein metabolism. PMID- 4304651 TI - [Control of renin secretion. 1. Renin secretion in the perfused dog kidney]. PMID- 4304652 TI - Metabolism of adenosine 3',5'-monophosphate by epithelial cells of the toad bladder. AB - When whole urinary bladders of the toad were incubated with adenosine 3',5' monophosphate-(3)H (cyclic AMP-(3)H) > 95% of the radioactivity could be extracted from the tissue with trichloroacetic acid (TCA). The TCA-soluble radioactivity was separable by cation-exchange (Dowex-50) chromatography into residual cyclic AMP-(3)H, 5'-AMP-(3)H, adenosine diphosphate (ADP)-(3)H and inosine-(3)H. Thus, neither substantial tight binding of cyclic AMP to TCA precipitable cell constituents nor any novel metabolite of cyclic AMP were found. On exposure of cyclic AMP-(3)H to a crude homogenate of the epithelial cells scraped from the mucosal face of the bladder, the principal metabolite was inosine-(3)H, whereas 5'-AMP-(3)H was either absent or present in undetectible amounts. However, when the homogenate included added 5'-AMP (2 x 10(-2) mole/liter), substantial quantities of 5'-AMP-(3)H were recovered. Metabolism of cyclic AMP-(3)H by homogenates of the epithelial cell scrapings from the bladder was strongly stimulated by alkalinization over the range in pH of 6-9. Theophylline inhibited metabolism of cyclic AMP only to a limit of 50%, the inhibition being limited to the OH(-)-stimulated component. These results suggest the possibility that a second pathway for metabolism of cyclic AMP may exist. If such is the case, its relationship, if any, to the ultimate biological effects of cyclic AMP within cells will be studied. PMID- 4304653 TI - Regulation of DNA synthesis in fat cells and stromal elements from rat adipose tissue. AB - The incorporation of tritiated thymidine into the deoxyribonucleic acid (DNA) of adipose fat and stromal cells was followed under a variety of conditions. After in vitro incubation of adipose slices or up to 2 days after in vivo injection of the isotope, all DNA radioactivity was in the stromal cell fraction. From 2 to 15 days after thymidine injection total tissue DNA radioactivity was constant, while between 2 and 5 days after injection label in fat cell DNA increased markedly. Thus new labeled fat cells, initially collected in the stromal pool, required 2-5 days after completion of DNA synthesis to accumulate sufficient lipid to be harvested in the fat cell fraction. Fasting before thymidine injection practically abolished DNA synthesis in primordial fat cells and reduced less drastically formation of stromal elements. However fasting sufficient to deplete lipid stores by 50% neither destroyed mature fat cells nor impaired their capacity to reaccumulate fat with refeeding. Other studies evaluated the role of new fat cell formation in the process of lipid accretion accompanying refeeding. These experiments indicated that at least during the early phase of rapid weight gain, accumulation of fat was due to deposition of triglyceride in existing cells rather than to accelerated formation of new fat cells. Studies with hypophysectomized rats demonstrated that pituitary ablation variably affected stromal DNA synthesis and nearly abolished the formation and (or) maturation of primordial fat cells. In these animals growth hormone markedly enhanced thymidine incorporation into stromal DNA but had no effect on fat cell precursors. In intact animals the predominant effect of growth hormone was also on the stromal fraction, although an action of the hormone of lesser magnitude on fat cell precursors was also evident. PMID- 4304654 TI - Metabolism and rate of secretion of aldosterone in the bullfrog. AB - A study of the metabolism of aldosterone in the bullfrog was undertaken to provide a measurable metabolite for the indirect isotope dilution technique for measuring secretory rates. The rate of excretion of labeled aldosterone was considerably slower in the frog than in man and made necessary the collection of excretory products for 5 days to insure reasonably complete recovery of metabolites. The major identifiable metabolite was a tetrahydro derivative subsequently identified as 3beta-hydroxy-5beta-tetrahydroaldosterone. This metabolite was excreted partly in the free form and partly as a glucuronic acid conjugate. The pH 1-hydrolyzable conjugate of aldosterone was not detected. For the measurement of secretory rates, aldosterone-(3)H was injected into the dorsal lymph space and the animal placed in a bath to provide an environment of constant electrolyte composition and intake and a means of collecting excretory products. Urine and bath fluid were collected for 5 days, tetrahydroaldosterone was isolated, and its specific activity determined for the calculation of the aldosterone secretory rate. The rate of secretion of aldosterone in the bullfrog was increased by a tap water bath and by bovine adrenocorticotropic hormone, decreased by a saline bath and by dexamethasone, and unchanged by valine-5 angiotensin amide. PMID- 4304655 TI - The activity of enzymes in the rabbit uterus and effect of progesterone and oestradiol. PMID- 4304656 TI - Lack of effect of dexamethasone on the adrenocortical response to corticotrophin in sheep with adrenal autotransplants. PMID- 4304657 TI - Lipolysis in chicken adipose tissue in vitro. PMID- 4304658 TI - Building on a bone; or how Dr. Krogman parlays skeletal elements into diverse careers. PMID- 4304659 TI - [Proliferation kinetics of autochthonous malignant tumors following hypophysectomy]. PMID- 4304661 TI - Thyroxine-induced acute enhancement of pituitary-adrenal function in the rat. PMID- 4304660 TI - [Primitive liver neoplasm with monoclonal dysglobulinemia of IgA type]. PMID- 4304662 TI - Failure of corticosterone to suppress pituitary ACTH release in rats exposed to various noxious stimuli. PMID- 4304663 TI - Fat embolism: an experimental study (II). Evaluation of smooth muscle relaxants in its treatment. PMID- 4304664 TI - Mucinous adenocarcinoma of the urachus. PMID- 4304665 TI - Radioautographic and radiochemical analysis of postnatal collagen formation in mouse dermal skin. PMID- 4304666 TI - [Characterization of muscle fibers in a cephalopod (Octopus vulgaris Lam.), based on some histoenzymologic reactions]. PMID- 4304667 TI - Cell culture techniques for primary isolation of Marek's disease-associated herpesvirus. PMID- 4304668 TI - The morphologic response of the turkey oviduct to certain pathogenic agents. PMID- 4304669 TI - Pleliminary observations on possible synergism between infectious laryngotracheitis virus and hemophilus gallinarum. PMID- 4304670 TI - Evidence for a herpesvirus as an etiologic agent of marek's disease. PMID- 4304671 TI - Transmission of classical Marek's disease by affected and carrier birds. PMID- 4304672 TI - Early changes in bursa of fabricius from Marek's disease. PMID- 4304673 TI - Studies on an ocular infectious laryngotracheitis vaccine. PMID- 4304674 TI - Avian leukosis-sarcoma viruses and antibody in field flocks, and their relationship to "leukosis" mortality. PMID- 4304675 TI - Owl pox inclusion-body formation in skin epithelium of chicks. PMID- 4304676 TI - [Experimental peritoneal lesions caused by various silica dusts]. PMID- 4304677 TI - Polyneuritis. PMID- 4304678 TI - [Single stage nephrectomy and heminephrectomy in a child for bilateral Wilm's tumor]. PMID- 4304679 TI - Induction of sexual excitement with intraventricular ACTH; permissive role of testosterone in the male rabbit. PMID- 4304680 TI - Working hypothesis: viral etiology of autoimmune diseases. PMID- 4304681 TI - [Outbreak of food poisoning caused by Cl. perfringens]. PMID- 4304682 TI - [On the thermoresistance of Cl. prepfringens, causal agent of alimentary toxinfection. II]. PMID- 4304683 TI - 'Granular-cell myoblastoma' in the horse. A report of 4 cases. PMID- 4304684 TI - Blood cells and chemistry of young chickens during daily ACTH and cortisol administration. PMID- 4304685 TI - The availability of phytate phosphorus in soybean meal before and after treatment with a mold phytase. PMID- 4304686 TI - Effect of phytate on the calcium requirement of chicks. PMID- 4304687 TI - Radiosensitivity and biological properties of tumors. XIV. Correlation between mitochondrial structure, oxidative metabolism, and radiosensitivity. PMID- 4304688 TI - Prevention by arginine glutamate of the carcinogenicity of acetamide in rats. PMID- 4304689 TI - Altered sensitivity to drugs following repeated injections of a cholinesterase inhibitor to rats. PMID- 4304690 TI - [Cl. perfringens in the intestinal contents of newborn infants]. PMID- 4304691 TI - [Clinico-anatomical parallels in adenoviral pneumonia]. PMID- 4304692 TI - [The state of acetylation processes and of some lipid metabolid indices in children with infectious nonspecific arthritis]. PMID- 4304693 TI - [Etiology and pathogenesis of croup in acute respiratory disease in children]. PMID- 4304694 TI - [Necrotic enteritis caused by Cl. perfringens of the C and F types (review of the literature)]. PMID- 4304695 TI - An autopsy case of islet-cell carcinoma with Cushing's syndrome. PMID- 4304696 TI - Role of host factors in the induction of leukemia by radiation and virus. PMID- 4304697 TI - [Histochemistry of the mucus secreted by a tumor of the human colon (Z 516) in long duration organotypic culture]. PMID- 4304698 TI - [Apropos of a case of severe hypoglycemia. Present possibilities of diagnosis and treatment]. PMID- 4304699 TI - [On surgical treatment of the glomus jugulare tumor]. PMID- 4304700 TI - [A simple method of plastic surgery of finger syndactylia in children]. PMID- 4304701 TI - [The surgical treatment of syndactylia]. PMID- 4304703 TI - [Neuropathological aspects of Karwinskia humboldtiana intoxication. Experimental study]. PMID- 4304702 TI - [Pulmonary adenomatosis or alveolar adeno-carcinoma]. PMID- 4304704 TI - Effects of bleomycin on transplantable mouse tumors. PMID- 4304705 TI - Antiviral activity of mycophenolic acid. Studies on antiviral and antitumor antibiotics. IV. PMID- 4304706 TI - Further studies of the infectivity and stability of extracts and homogenates derived from scrapie affected mouse brains. PMID- 4304707 TI - The use of bacteriocidal agents in the primary isolation of Mycoplasma mycoides. PMID- 4304708 TI - Foot-and-mouth disease in wildlife in Rhodesia and other African territories. A serological survey. PMID- 4304709 TI - The isolation of adenoviruses and enteroviruses from pig tissues. PMID- 4304710 TI - Carcinogenesis in tissue culture. 8. Spontaneous malignant transformation of rat liver cells in long-term culture. PMID- 4304711 TI - Lipids of cancer tissues. IV. Glycolipids of human gastric carcinoma. PMID- 4304712 TI - Chemical structure of the main glycolipid of hog erythrocytes. PMID- 4304713 TI - On the glucocerebroside in the brain of old patients. PMID- 4304714 TI - [Change in the activity of certain enzymes in the blood serum in mechanical jaundice during the pre- and postoperative periods]. PMID- 4304715 TI - [New technic of myeloradiculography with resorbable water soluble iodide contrast media without spinal anesthesia]. PMID- 4304716 TI - [On the problem of foreign viruses in viral vaccines, produced on the chick embryo base. 1. Group of poultry tumor viruses]. PMID- 4304718 TI - [Epileptic manifestations in a patient with pancreatic insulinoma]. PMID- 4304717 TI - [Solubility of drugs as criterion for drug liberation from fat-like, galenic bases (Cetylium phthalicum, lasupol G) with reference to viscosity increasing adjuvant substances]. PMID- 4304719 TI - [Clinical aspects and etiology of angina in children with adenovirus infection]. PMID- 4304720 TI - [Clinico-laboratory parallels in influenza and adenoviral infection in children in the 1st year of life]. PMID- 4304722 TI - Effect of ultraviolet light on the epidermis. 3. Histochemistry of cell respiration and phosphorylation. PMID- 4304723 TI - [Study on cytomegalovirus infection. 1. Study on cytomegalic inclusion disease in infants using autopsy materials]. PMID- 4304721 TI - [On the frequency of astrocytic glia changes ("liver glia") in hepatogenic diseases, especially liver cirrhosis, and their dependency of the functional state of the organ]. PMID- 4304724 TI - [Study on cytomegalovirus infection. 2. Study on human cytomegalovirus infection in cultured cells]. PMID- 4304725 TI - Serum "Angiotensinase activity" and female steroidal hormones. PMID- 4304726 TI - Ectopic inhibition of the complexes of the electron transport system by rotenone, piericidin A, demerol and antimycin A. PMID- 4304727 TI - Site-specific uncoupling and inhibition of oxidative phosphorylation by biguanides. II. PMID- 4304729 TI - Detection by immunodiffusion of mouse mammary tumor virus in milk samples and correlation with tumor development. PMID- 4304728 TI - Activation Ca2+ uptake by acetyl phosphate in muscle microsomes. PMID- 4304730 TI - Profiles of total ribonucleoprotein particles from normal rat liver, primary liver tumors, and Novikoff hepatoma. PMID- 4304731 TI - An ultrastructural study of the toxic and carcinogenic effects of 2-amino-5 azotoluene on the livers of schistosome-infected and uninfected mice. PMID- 4304732 TI - The effect of phleomycin on the replication of papovavirus SV40 and other DNA viruses in simian cells. PMID- 4304734 TI - Chromosomes of "minimal deviation" hepatomas: a further report on diploid tumors. PMID- 4304733 TI - Ultrastructural modifications of the cell surface and intercellular contacts of some transformed cell strains. PMID- 4304735 TI - Protection against mammary tumors in mice by immunization with purified mammary tumor virus preparations. PMID- 4304736 TI - Effect of ethanol exposure during embryogenesis and the neonatal period on the incidence of hepatoma in C3H male mice. PMID- 4304738 TI - Family group counseling. PMID- 4304737 TI - Delays in arranging aftercare. PMID- 4304739 TI - Inhibitory effect of lysolecithin on electron transfer from NADH to cytochrome b. PMID- 4304740 TI - Plasma membranes of the rat liver. Isolation and enzymatic characterization of a fraction rich in bile canaliculi. AB - A method is described for the rapid isolation of a plasma membrane fraction containing a high concentration of intact bile canaliculi from the rat liver. Isolated bile canaliculi retain most of the ultrastructural features exhibited in the intact liver cell. The final fraction contains 5'-nucleotidase activity at approximately the same concentration as that in previous preparations of plasma membranes. In the presence of 0.01 M Mg(++), 5'-nucleotidase exhibits a double pH optimum at pH values of 7.5 and 9.5. The activities of glucose-6-phosphatase and alkaline phosphatase are present in low amounts. Cytochrome P-450 is not detectable. Na(+)-K(+)-activation of ATPase is observed to the extent of 20-36% in about half of the assays. The availability of a method for preparation of intact bile canaliculi should prove useful for studying the biochemical events associated with the transport of bile constituents into canaliculi. PMID- 4304741 TI - Morphogenetic aspects of multilayering in Petri dish cultures of human fetal lung fibroblasts. AB - Randomly seeded Petri dish cultures of embryonic human lung fibroblasts generate, in the course of their growth, highly ordered cellular arrangements. Thick, bilaterally symmetrical ridges with an axial polarity and an orthogonal, multilayered internal organization are observed within stationary cultures. The generation of these structures has been investigated. Ridges result from the spontaneous aggregation of cells in postconfluent cultures brought about by directed cell movements. These movements are promoted by the localized production of extracellular matrix sheets containing collagen, which provide new substrates for cellular colonization. Cells that have colonized one matrix substrate may secrete another above themselves, which will in turn be colonized. By a continuation of this cycle, thick stacks consisting of alternate layers of cells and matrix are produced to yield the observed aggregations. The distribution and shape of ridges in a culture imply that matrix substrates are confined to specific locations. The suggested control hypothesis assumes that all the cells in fibroblast cultures are potential producers of a single species of matrix. The serviceability of this matrix as a substrate for cellular colonization, however, is destroyed if the producer cells are motile. Matrix substrates, therefore, are only made by nonmotile cells. PMID- 4304743 TI - Incorporation of radioactivity from 14C-sugars into macromolecules in poliovirus infected or guanidine-treated HeLa cells. PMID- 4304742 TI - Ultrastructural and biochemical changes in brown fat in cold-exposed rats. AB - During the first 3 days of exposure of rats to 5 degrees C, the nitrogen concentration of interscapular brown fat increased by 50% and remained at this elevated level for the duration of the 8-wk observation period, while the mass of tissue increased fourfold. The concentration of both DNA and RNA per unit nitrogen reached a maximum after 3 days, then declined; however, the total quantity of each continued to rise. The concentration of various respiratory enzymes decreased during the first few days and then increased, but at different rates. The morphological changes in mature brown fat cells during cold acclimation were observed to be: a reduction in fat droplet size during the first 3 days, followed by a gradual increase in size through 6 wk in the cold; a continual increase in the amount of intermitochondrial ground substance during the first 3 wk, with increased granularity and glycogen content after 1 wk; initial disappearance of glycogen between mitochondria, followed by the reappearance of a few isolated particles in the intermitochondrial ground substance after 1 wk in the cold; initial increase in the density of intramitochondrial matrix for the first 3-4 days, followed by a gradual return to the control density; loss in integrity of mitochondrial outer membranes during the first 4 days, followed by gradual but incomplete restoration; temporary loss of the dense material in lipid droplets during the first 24 hr, with return after 1 wk in the cold; and a 40% increase in mitochondrial diameter within 1 day, followed by a decrease in diameter within 1 wk to a constant value about 15% larger than the controls. PMID- 4304744 TI - Incorporation of lipids into herpes simplex virus particles. PMID- 4304745 TI - A metastatic Wilm's tumour in the nasopharynx. PMID- 4304746 TI - Results of a comparison of serologic tests used to detect human antibodies to a herpesvirus (HLV) associated with Burkitt's lymphoma. PMID- 4304747 TI - Growth in vitro and ultrastructure of cells from a medullary carcinoma of the human thyroid gland: transformation by simian virus 40 and evidenc of thyrocalcitonin and prostaglandins. PMID- 4304748 TI - [Anterior pituitary gland function tests, with special reference to ACTH]. PMID- 4304749 TI - Antiviral effect of daunomycin. PMID- 4304750 TI - [Clinical manifestations of the untoward reaction of corticosteroid therapy in children with rheumatism]. PMID- 4304752 TI - [Histochemical research of the mucopolysaccharides in the so-called mixed tumors of the salivary glands]. PMID- 4304751 TI - [Effects of stilbestrol and similar drugs on the oxidation reduction of cytochrome b]. PMID- 4304753 TI - [The granulosa cell tumor of the oral cavity (Abrikosoff's myoblastoma) 3 clinical cases]. PMID- 4304754 TI - Auditorially evoked responses. A tool for assessing the patient's ability to hear during various states of consciousness. PMID- 4304755 TI - [Enzyme studies in the oxygen damaged respirated rabbit lung]. PMID- 4304756 TI - [The behavior of granulocyte oxidases in neuroleptoanalgesia]. PMID- 4304757 TI - [Anti-and orthodromic response of respiratory neurons in the brain stem]. PMID- 4304758 TI - Fibrinogen response to corticotropin preparations in rabbits. PMID- 4304759 TI - Adrenal steroidogenesis and serum renin in rats bred for juxtaglomerular granularity. PMID- 4304760 TI - Mechanism of neuromuscular blockade by tetraethylammonium. PMID- 4304761 TI - [Studies on the histoenzymology of the white rat's ovary during ontogenesis and the estral cycle]. PMID- 4304762 TI - Characterization of bacteria by gas chromatography: comparison of trimethylsilyl derivatives of whole-cell hydrolysates. AB - A method for the formation of the trimethylsilyl (TMS) derivatives of the whole cell hydrolysate of bacteria was developed. The TMS derivatives were examined by gas-liquid chromatography. TMS profiles of various bacteria at the genus and species level were compared. Differences in TMS profiles of Listeria, Neisseria, and Clostridium were significant as were differences between the TMS profiles of C. perfringens and C. sporogenes. Two types of C. perfringens, two serotypes of L. monocytogenes, and one culture of C. sporogenes and N. meningitidis were studied. The possible application of TMS profiles as an aid in differentiating closely related organisms which are troublesome to separate by conventional means is discussed. PMID- 4304763 TI - Sporulation, heat resistance, and biological properties of Clostridium perfringens. AB - A sporulation medium for 134 Clostridium perfringens strains, including types A, B, C, D, E, and F, was devised according to Grelet's observation that sporulation occurred when cultural environment became limited in any nutritional requirement indispensable for the growth of the organism. Sporulation took place most prominently when 10% cooked-meat broth (pH 7.2) containing 3% Proteose Peptone and 1% glucose was used for the preculture and 2% Poli Peptone medium (pH 7.8) was used for the subculture medium. Sometimes, terminal spores could be observed. A correlation between sporulation and heat resistance was examined by use of C. perfringens strains isolated from samples heated at different temperatures. Almost all strains isolated from unheated samples and from those heated at lower temperatures gave rise to spores in our sporulation medium, but the spores were weakly heat-resistant, whereas strains isolated from samples heated at 100 C for 60 min were highly heat-resistant but sporulated poorly. A majority of these heat resistant strains were non-gelatinolytic and definitely salicin-fermenting. PMID- 4304764 TI - Antibiotic additives for the isolation of Chondrococcus columnaris from fish. PMID- 4304765 TI - Influence of adrenal cortical hormones on the norepinephrine-induced lipolysis. PMID- 4304767 TI - Plasma membranes of liver cells of the chick embryo. I. Isolation procedures. PMID- 4304766 TI - Specificity of the dehydrogenases of maize endosperm. PMID- 4304769 TI - Effects of ATP and Ca2+ on a K+-activated phosphatase from red blood cell membranes. PMID- 4304768 TI - Alpha-aminoisobutyric acid uptake in isolated mouse fat cells. PMID- 4304770 TI - A spin-label study of erythrocyte membranes. PMID- 4304771 TI - The stepwise acceleration of phosphatidyl choline synthesis in phytohemagglutinin treated lymphocytes. PMID- 4304772 TI - The chromatographic separation of phosphonolipids from their phospholipid analogs. PMID- 4304773 TI - The in vitro degradation of dihydrosphingosine. PMID- 4304774 TI - Isomerization of 5-androsten-3,17-dione by hepatic tissue. PMID- 4304775 TI - Steroid estrogen conjugates of hen's urine: formation in vivo of steroid estrogen monosulphates and disulphates from injected estradiol-17-beta. PMID- 4304776 TI - [Trials of immunization against fowl plague by inactivated virus]. PMID- 4304778 TI - Histologic changes in incipient carcinoma of the breast. PMID- 4304777 TI - Endocrine influences on human mammary cancer formation. A critique. PMID- 4304779 TI - Team approach tthe study of diseases of the breast. PMID- 4304780 TI - Genital herpetic infection. Association with cervical dysplasia and carcinoma. PMID- 4304781 TI - Urinary testosterone production and metabolism in man: sequential effects of dexamethasone, estrogen, ACTH and HCG. PMID- 4304782 TI - The effect of thyroxine and cortisol on some dehydrogenases and lysosomal enzymes activities in rat pineal cultures. PMID- 4304783 TI - Histochemistry of the pancreatic islets in golden hanster Mesocricetus auratus Waterhouse 1839. PMID- 4304784 TI - Nonequilibrium alpha adrenergic blockade and neuroleptic activity of N ethoxycarbonyl-1,dihydroquinoline (BC-347). PMID- 4304785 TI - Adrenalectomy in cases of severe renal sclerosis. PMID- 4304786 TI - [Sudden death in a young subject: tumor of lateral ventricle]. PMID- 4304787 TI - [Changes of alkaline phosphatase serum levels during D3 hypervitaminosis. Experimental research]. PMID- 4304788 TI - Granular-cell myoblastoma of the vulva. PMID- 4304789 TI - Malignant mixed mullerian tumors of the uterus. A clinicopathologic study of 9 patients. PMID- 4304790 TI - [Tablet preparation by direct pressing]. PMID- 4304791 TI - [On the antimicrobial effect of peracetic acid. 5. Studies on the virucidal effect]. PMID- 4304793 TI - [On the treatment of climacteric and dysmenorrhoic symptomes with Presomen]. PMID- 4304792 TI - [Neonatal administration of cortex hormones of corticotropine in the rat, thymolytic effects and repercussions on the development of immunologic humoral reactivity]. PMID- 4304794 TI - [On the combination of conjugated estrogens with Librium (Menrium) for treatment of climacteric complaints]. PMID- 4304795 TI - Anaesthesia in patients with disturbances of cerebral and coronary circulation. PMID- 4304796 TI - The distribution of alkaline glycerophosphatase in the embryonic, regenerative, and normal mature tails of Hemidactylus bowringi (Gray). PMID- 4304797 TI - Selective celiac angiography with special reference to carcinoma of the liver. PMID- 4304798 TI - Conjugated estrogenic substances. PMID- 4304800 TI - Analytical applications of the phosphatase enzyme system. Determination of bismuth, beryllium and pesticides. PMID- 4304799 TI - Effects of reovirus type 1 on the developing mouse embryo. PMID- 4304801 TI - Determination of mercury residues in potatoes, grain and animal tissues using perchloric acid digestion. PMID- 4304802 TI - Genetic and epigenetic control of several isozymic systems in Tetrahymena. PMID- 4304803 TI - Genetic and epigenetic forms of malate dehydrogenase in Neurospora. PMID- 4304804 TI - Significance of substrate inhibition of dehydrogenases. PMID- 4304805 TI - Drosophila alcohol dehydrogenase: in vitro changes of isozyme patterns. PMID- 4304806 TI - Protection of lactate dehydrogenase isozymes from heat inactivation and enzymatic degradation. PMID- 4304807 TI - An ESR study of short-lived radicals derived from pyrimidines in aqueous solution. PMID- 4304808 TI - Studies on ribonucleic acid synthesis in nuclei isolated from rat liver. PMID- 4304809 TI - Ribonucleic acid synthesis in relation to precursor pools in regenerating rat liver. PMID- 4304810 TI - [Study of the effects of methylation on the behavior of DNA]. PMID- 4304811 TI - Symptomatic optic neuritis (etiological factors in acute optic neuritis). PMID- 4304812 TI - Psychological factors and prognosis in peripheral neuropathy. PMID- 4304813 TI - The experimenter variable in dream research. PMID- 4304814 TI - Sleep patterns and EEG recordings in twin idiot savants. PMID- 4304815 TI - [Deficiency of cytochrome oxidase in Saccharomyces cerevisiae strains requiring threonine for growth. 1. Genetic relationships]. PMID- 4304816 TI - [Deficiency of cytochrome oxidase in Saccharomyces cerevisiae strains requiring threonine for growth. 2. Metabolic relationships]. PMID- 4304817 TI - The effect of vitamin A deficiency on myelination in the central nervous system of the rat. PMID- 4304818 TI - [Epidemiology of Japanaese B encephalitis]. PMID- 4304819 TI - [Ultramicromorphologic study of cervical cancer of the human uterus]. PMID- 4304820 TI - [Clinical aspects of metastatic chorionic tumors]. PMID- 4304821 TI - The effect of antirenin on the blood pressure of the rat with exprimental renal hypertension. PMID- 4304822 TI - [Electron microscopic study of a case of insulinoma, compared with normal beta cells of the islets of the same person]. PMID- 4304823 TI - On lumpers and splitters, or the nosology of genetic disease. PMID- 4304824 TI - Neuropathology. PMID- 4304825 TI - Pharmacology of the central nervous system. PMID- 4304826 TI - Neuro-endocrine relationships. PMID- 4304827 TI - Peripheral nerve surgery. PMID- 4304829 TI - Effects of anticonvulsant drugs upon patterns of seizure discharge and brain thresholds: some implications for memory mechanisms. PMID- 4304828 TI - The neuroses. PMID- 4304830 TI - The after-care of the patient in the x-ray department. PMID- 4304831 TI - [Acute necrosing encephalitis in adults: demonstration of the herpesvirus by electron microscopy]. PMID- 4304832 TI - [Chemical substances involved in the neural conduction of peripheral nerves]. PMID- 4304833 TI - Gynecology and obstetrics. PMID- 4304834 TI - Clinical and pathologic observations after orthotopic transplantation of the human liver. PMID- 4304835 TI - [Oncological aspects of immunological endocrinology]. PMID- 4304836 TI - Observations on distribution of NADH oxidase in particles from dark-grown and light-grown Rhodospirillum rubrum. PMID- 4304837 TI - An EPR signal generated by the ethanolamine deaminase-coenzyme B 12 complex in the presence of substrate. PMID- 4304838 TI - Epinephrine induced formation of adenosine 3', 5'-monophosphate in mouse skeletal muscle. PMID- 4304839 TI - Effect of cytosine arabinoside 5'-triphosphate on mammalian DNA polymerase. PMID- 4304841 TI - Chromosomal evolution of a secondary clone from the SV40 transformed human cell line, W18 Va2. PMID- 4304842 TI - Nucleotide sequence studies with ribonucleic acids from liver and hepatoma of the rat using DNA-RNA hybridization. PMID- 4304840 TI - Evidence for direct hydrogen transfer during glyceraldehyde-3-phosphate dehydrogenase catalysis. PMID- 4304843 TI - The effect of esteroproteases from mouse submaxillary gland on the growth of rat hepatoma cells in tissue culture. PMID- 4304844 TI - [Cytokinetic studies on human blood monocytes]. PMID- 4304845 TI - [The cytochemistry of mononuclear cells in Rebuck's skin window preparation]. PMID- 4304846 TI - [The monocyte leukemia]. PMID- 4304847 TI - [Studies on the genetic and environmental variability of serum fructose-1,6 diphosphate aldolase in monozygotic and dizygotic twins]. PMID- 4304848 TI - [Formation of complexes by pyrimidine derivatives. VII. Copper (II) complexes with adenine-1-oxide]. PMID- 4304849 TI - The relative nephrotoxicities of polymyxin B sulfate, sodium sulfomethyl polymyxin B, sodium sulfomethyl-colistin (colymycin), and neomycin sulfate. PMID- 4304850 TI - D-mannitol metabolism by Aspergillus candidus. AB - Pathways of mannitol biosynthesis and utilization in Aspergillus candidus NRRL 305 were studied in cell-free extracts of washed mycelia prepared by sonic and French pressure cell treatments. A nicotinamide adenine dinucleotide-linked mannitol-1-phosphate (M1P) dehydrogenase was found in French pressure cell extracts of d-glucose-grown cells, whereas a specific mannitol-1-phosphatase was present in extracts prepared by both methods. The existence of these two enzymes indicated that mannitol may be synthesized in this organism by the reduction of fructose-6-phosphate. A specific nicotinamide adenine dinucleotide phosphate linked mannitol dehydrogenase was also identified in both extracts. This enzyme may have been involved in mannitol utilization. However, the level of the mannitol dehydrogenase appeared to be substantially reduced in extracts from mannitol-grown cells, whereas the level of M1P dehydrogenase was increased. A hexokinase has been identified in this organism. Fructose-6-phosphatase, glucose isomerase, and mannitol kinase could not be demonstrated. PMID- 4304851 TI - The development of patterened activity by implanted ganglia and their peripheral connexions in Periplaneta americana. PMID- 4304852 TI - Excitation and habituation of the crayfish escape reflex: the depolarizing response in lateral giant fibres of the isolated abdomen. PMID- 4304853 TI - The synaptic link between the sensory and motoneurones in the eye-withdrawal reflex of the crab. PMID- 4304855 TI - [The importance of the morphologic structure of the tumor to the outcome of surgical treatment of stomach cancer]. PMID- 4304854 TI - Deprivation of paradoxical sleep and brain glycogen. PMID- 4304856 TI - Case for diagnosis. PMID- 4304857 TI - [Influence of ACTH on some aspects of hydrocarbonate metabolism. II. Development of glycemia, fructosemia and phosphohexose isomerase (IFH) in adrenalectomized and normal rats]. PMID- 4304858 TI - New light-sensitive cofactor required for oxidation of succinate by Mycobacterium phlei. AB - Irradiation of the electron transport particles of Mycobacterium phlei with light at a wavelength of 360 manometers resulted in a loss of oxidase activities of succinate and the reduced form of nicotinamide adenine dinucleotide. The lesion in the two pathways caused by irradiation of the particles differs. The succinoxidase pathway was more labile to irradiation than the pathway linked to nicotinamide adenine dinucleotide. Restoration of succinoxidase activity (up to 50 to 60 percent) occurred on addition of a thermostable, water-soluble material obtained from Mycobacterium phlei cells or with an extract of mitochondria from boiled rat liver. Other known cofactors, such as flavine adenine dinucleotide, flavine mononucleotide, benzo- and naphthoquinones, as well as sulfhydryl agents, failed to restore succinoxidase activity after irradiation. Water-soluble material from Mycobacterium phlei appears to function between the flavoprotein and cytochrome b on the succinoxidase pathway. In contrast to the requirements for restoration of the pathway linked to nicotinamide adenine dinucleotide, restoration of succinoxidase does not occur with quinones or other cofactors such as flavine adenine dinucleotide. PMID- 4304859 TI - Molecular order of participation of inhibitors (or activators) in biological systems. AB - From a Hill plot it is frequently possible to determine whether exactly one, two, or several inhibitor (or activator) molecules are involved in a critical rate determining biological process. PMID- 4304860 TI - [Evolution of early hepatoma in the rainbow trout]. PMID- 4304861 TI - [Electron microscopic study of viral particles in the mouse thymus gland during leukemogenesis with urethane]. PMID- 4304862 TI - [Tumors of arterio-venous anastomoses (glomuses) as a cause of patients' protracted suffering]. PMID- 4304863 TI - [Clinico-roentgenologic features of a malignant synovioma following a prolonged course]. PMID- 4304864 TI - [Paradoxes of acute appendicitis]. PMID- 4304865 TI - [Behavior of the spleen and adrenal glands during the evolution of tumoral grafts in the rat]. PMID- 4304866 TI - [On the alpha glycerophosphate dehydrogenase activity in the chick embryo brain]. PMID- 4304867 TI - [3H-thymidine autoradiography studies on the origin of reactive cells in the brain of mice infected with Japanese encephalitis virus]. PMID- 4304868 TI - Biochemistry of hypoxia: current concepts. II. Biochemical derangements associated with hypoxia and their measurement. PMID- 4304869 TI - The early effects of experimental exposure, manipulation, and temporary ischaemia on the rabbit kidney. A histological and biochemical study. PMID- 4304870 TI - Osteoclastoma of the petrous temporal bone. PMID- 4304871 TI - Freezing injury in relation to loss of enzyme activities and protection against freezing. PMID- 4304872 TI - Stability of purified foot and mouth disease virus after freeze-drying and storage. PMID- 4304873 TI - [Management of hirsutism using cyproterone acetate]. PMID- 4304874 TI - [A new test for the LH-releasing function of the hypothalamo-pituitary axis]. PMID- 4304876 TI - [Studies on glucose-6-phosphatase in liver and kidney. I. Basic properties of glucose-6-phosphatase in the rat liver and kidney]. PMID- 4304875 TI - [Changes in adenohypophysial RNA, plasma ACTH activity and plasma corticosterone following various acute stimuli in rats]. PMID- 4304877 TI - [Experimental studies on adrenal cortex hypofunction. Metabolic changes of the adrenal gland of rabbits under short- or long-term administration of synthetic steroid hormones or ACTH]. PMID- 4304878 TI - Adrenal oxidative enzymes in ox and sheep. The histochemical demonstration of some pathways involved in chromaffin granule synthesis. PMID- 4304879 TI - Mottled areas of intra-abdominal calcification. PMID- 4304880 TI - [Anaerobic wound infection in changing times]. PMID- 4304881 TI - Experience with a rapid oral metyrapone test and the plasma ACTH content in determining the cause of Cushing's syndrome. PMID- 4304882 TI - Plasma glucose response to natural vasopressin in maturity onset diabetics and adult nondiabetics. PMID- 4304883 TI - [Endocrinological study on patients subjected to orbitoventromedical undercutting, with special reference to 17-hydroxycorticosteroid excretion]. PMID- 4304884 TI - [Several problems of the clinical aspects and cytological diagnosis of inclusion cytomegaly in children in the 1st year of life]. PMID- 4304885 TI - [Wilms' tumor in a horseshoe kidney]. PMID- 4304886 TI - [Allergy induced simultaneously by isoniazide, streptomycine and P.A.S]. PMID- 4304887 TI - [Combination of chemotherapy and electrocoagulation in the treatment of gingival cancers]. PMID- 4304888 TI - [Studies on the localization of the herpes simplex virus after healing of the skin recidives. Cultivation of cells from the area hit by the recidive oruption]. PMID- 4304889 TI - The mechanism of aluminium in the prevention of pneumoconiosis. PMID- 4304890 TI - [A study of the properties of host antigens in the structure of myxoviruses]. PMID- 4304891 TI - [On the question of interferon production in mice]. PMID- 4304892 TI - [An outbreak of acute respiratory infections among adults caused by adenovirus serotype 14]. PMID- 4304893 TI - [Dynamics of the inactivation of poliomyelitis and ECHO 7 viruses by gamma-rays]. PMID- 4304894 TI - [A study of the sensitivity to adenoviruses of SOTs calls treated with kanamycin]. PMID- 4304895 TI - [The use of hydroxylamine in the preparation of inactivated viral antigens]. PMID- 4304896 TI - [A study of the correlation of the RCT-40 marker of poliomyelitis type 3 virus with neurovirulence for monkeys]. PMID- 4304897 TI - [Incorporation of the tumor determinant of SV40 virus in adenoviruses]. PMID- 4304898 TI - [On the immunology of guinea pig tumors induced by Rous sarcoma virus]. PMID- 4304899 TI - [A comparative study of cytologic changes in various cell cultures infected with human para-influenza viruses types 1, 2, 3 and 4]. PMID- 4304900 TI - [Japanese encephalitis in the Primorsk region in 1965]. PMID- 4304901 TI - [On the mechanism of the cytopathic effect of pertussis microbes on tissue culture]. PMID- 4304902 TI - [Prevention of Japanese encephalitis in the Primorsk region]. PMID- 4304903 TI - The proposed ACGIH mass limits for quartz: review and evaluation. PMID- 4304904 TI - Effects of sucrose and dactinomycin on hepatic acid hydrolases. PMID- 4304905 TI - The one-hour synthetic corticotrophin test for rapid assessment of adrenal function. PMID- 4304906 TI - [Induction of mammary tumors by injections of PS leukemia acellular extracts into young mice of other strains]. PMID- 4304908 TI - On the occurrence of neoplasms in domestic fowl--an angiosarcoma and a malignant hepatoma. PMID- 4304907 TI - Use of intravenous vitamin D3 in the detection of vitamin D deficiency. PMID- 4304909 TI - [Studies on the isolation of variola virus in a continuous monkey kidney cell culture, and properties of the isolated virus]. PMID- 4304910 TI - Cystic abdominal tumor in a 66 year old man. PMID- 4304911 TI - Amino acid activation and formation of amino acyl s-RNA in bovine parotid gland. PMID- 4304912 TI - Subacute denervation: a means of disclosing mammalian motor nerve terminals as critical sites of acetylcholine and facilitatory drug actions. PMID- 4304913 TI - Investigations on a series of heterocyclic hemicholinium-3 analogs. PMID- 4304914 TI - Neurogenic basis for the rise in blood pressure evoked by nicotine in the cat. PMID- 4304915 TI - Subcellular localization of monoamine oxidase in rat tissues. PMID- 4304916 TI - Effect of cold on plasma protein-thyroxine interaction in the guinea pig. PMID- 4304923 TI - Cell physiology. Essential element. PMID- 4304920 TI - Microstructure of "lypochondria" from cultured cells. PMID- 4304924 TI - Temperature dependence of the EPR signal in tendon collagen. PMID- 4304925 TI - Detection and investigation of a new type of ESR signal characteristic of some tumour tissues. PMID- 4304926 TI - New vitamin D metabolite localized in intestinal cell nuclei. PMID- 4304927 TI - Curve-fitting of allosteric binding data. PMID- 4304928 TI - Facilitation of peptide synthesis by the use of 4-picolyl esters: synthesis of va15-angiotensin II. PMID- 4304929 TI - Susceptibility of the domestic pig to influenza B virus. PMID- 4304930 TI - Significance of a complement-fixing antigen associated with herpes-like virus and detected in the Raji cell line. PMID- 4304931 TI - Ependymomas induced in hamsters inoculated with an avian adenovirus (CELO). PMID- 4304932 TI - The histographic analysis of human muscle biopsies with regard to fiber types. 2. Diseases of the upper and lower motor neuron. PMID- 4304933 TI - Israel. PMID- 4304934 TI - Clinical laboratory experiences with a more attenuated Enders' measles virus vaccine (Moraten) combined with smallpox vaccine. PMID- 4304936 TI - Photoprocesses and molecular associations. PMID- 4304935 TI - Actions of sympathomimetic amines and their antagonists on skeletal muscle. PMID- 4304937 TI - Some electron spin resonance characteristics of human female breast tumours. PMID- 4304938 TI - Drug addicts in a therapeutic community. Outline on the California Rehabilitation Center Program, Corona. PMID- 4304939 TI - A treatment strategy of dealing with an entrenched long hospitalized patient group. PMID- 4304940 TI - Psychiatric aftercare in a general hospital. A system of prevention in the community. PMID- 4304941 TI - Changes in drinking behavior in rats in response to large doses of alcohol. PMID- 4304942 TI - [Surgical management of liver cancer with reference to primary hepatoma]. PMID- 4304944 TI - Retinal processing of visual images. PMID- 4304943 TI - [Enzyme histochemistry of human liver]. PMID- 4304945 TI - Hydroxamic acids in nature. AB - The hydroxamic acid bond occurs in products from fungi, yeast, bacteria, and plants. The -CON(OH)-bond arises by oxidation of a free or bound amino group in a unit structure which is often closely related to conventional amino acids. Products are known with one, two, or three hydroxamic acid groups per molecule. The chemistry of the ferrichrome type compounds, which are ferric trihydroxamate containing peptides, has been worked out in detail and includes a complete crystallographic analysis of the ferrichrome A molecule. The trihydroxamates form potent complexes with ferric ion, called siderochromes, and these are believed to play a role in the metabolism of the metal ion in microorganisms. The actual physiological activity observed ranges from that of growth factor, antibiotic, antibiotic antagonist, tumor inhibitor or cell-division factor. The precise molecular mechanism whereby these substances exert their potent beological activity remains to be elucidated. PMID- 4304946 TI - Selective release of enzymes from bacteria. AB - A group of hydrolytic enzymes, including phosphatases and nucleases, is selectively released from E. coli and certain other Gram-negative bacteria by a process designated as osmotic shock. This procedure involves exposure of the cells to ethylenediaminetetraacetate (EDTA) in 0.5 molar sucrose followed by a sudden osmotic transition to cold, dilute MgCl(2). Osmotic shock also results in an alteration of the permeability barrier of the bacterial cell and a depletion of the pool of acid-soluble nucleotides, but there is no loss of viability. On being restored to growth medium, the shocked cells recover after a lag period. Formation of spheroplasts by treatment with EDTA and lysozyme leads to selective release of the same group of enzymes. We believe that the selectively released enzymes are confined in a region between the bacterial cell wall and the cytoplasmic membrane. Histochemical studies indicate such a localization. Further, the enzyme activities are measurable with intact cells, even when the substrate is a nucleotide, to which whole cells are impermeable. Another piece of evidence concerns a mutant E. coli with a defective cell wall. In contrast to normal bacteria, this organism loses one of these enzymes into the medium in the course of growth. After osmotic shock, the bacteria show reduced uptake of sulfate,betagalactosides, galactose, and certain amino acids. Furthermore, the shock treatment causes the release of nondialyzable factors able to bind sulfate, galactose, and the same amino acids. A possible interpretation of these observations is the following: the binding proteins occupy sites near the bacterial surface, and they may be components of active transport systems responsible for the concentrative uptake of these nutrients. PMID- 4304947 TI - Dormin (Abscisin II), inhibitor of plant DNA synthesis? AB - Dormin (abscisin II), inhibits growth of Lemna minor cultures. At 1 part per million (3.8x10(-6)M), the culture appears nearly completely dormant but can be revived readily by transferring it to fresh medium free of dormin. The cytokinin benzyladenine, but not auxin or gibberellin, will counteract the dormin effect. Quantitative restoration of normal growth by cytokinin, however, can be achieved only if the dormin concentration does not exceed a critical level. Separation, after phenol-detergent extraction, of nucleic acids on methylated albumin kieselguhr columns showed suppression of nucleic acid synthesis by dormin in all fractions. Inhibition of the synthesis of the DNA fraction seems to precede that of RNA. Cytokinins reverse the process. They promote synthesis of all nucleic acid fractions, but again DNA seems to lead. Further work on the interaction of dormin with growth-promoting hormones might be facilitated by adopting the Monod model of allosteric transition, with, for example, DNA polymerase as the protein, dormin as the inhibitor, and cytokinin or other growth promoters as activators. PMID- 4304949 TI - "Galactose dehydrogenase", "nothing dehydrogenase," and alcohol dehydrogenase: interrelation. PMID- 4304948 TI - Primordial germ cells in blood smears from chick embryos. AB - The feasibility of studying avian primordial germ cells in blood smears has been demonstrated. Blood smears prepared from chick embryos of stages 13 to 15 (48 to 55 hours) contained primordial germ cells, which were revealed by the periodic acidSchiff reaction. The presence of glycogen in the cytoplasm of the primordial germ cells facilitated their selective identification. PMID- 4304950 TI - "Galactose dehydrogenase", "nothing dehydrogenase", and alcohol dehydrogenase: interrelation. PMID- 4304951 TI - Regulation of the adrenal cortex secretory pattern by adrenocorticotropin. AB - Adrenal gland homogenates from rabbits stimulated for 28 days with adrenocorticotropin have been shown to synthesize cortisol. The total amount of cortisol formed was the same whether progesterone-4-(14)C or Delta(5) pregnenolone-4-(14)C was used as exogenous substrate. However, when Delta(5) pregnenolone substrate was used the specific activity of the isolated cortisol was four times as great as when progesterone was used. PMID- 4304952 TI - Nature and mechanisms of oxygenases. PMID- 4304953 TI - Potassium, corticosterone, and adrenocorticotropic hormone release in vitro. AB - Incubation of rat adenohypophyses in a high concentration of potassium increases adrenocorticotropic hormone release. This increased release is suppressed by the addition of corticosterone to the incubating medium. Our findings are consistent with a process of "stimulus-secretion coupling" proposed for other glands and suggest that corticosterone may operate directly on the adenohypophysial cell membrane to inhibit releasing mechanisms. PMID- 4304954 TI - Encephalic cycles during sleep and wakefulness in humans: a 24-hour pattern. AB - Twenty-four-hour polygraphic tracings from normal humans indicate that a pattern of alternating periods of the presence and absence of rapid eye movement, shown to exist for normal sleep, exist over all 24 hours of the daily period. This finding suggests that the so-called sleep-dream cycle of human sleep is not specific to sleep, but is a general activity pattern of the brain. PMID- 4304955 TI - Information processing in the nervous system. PMID- 4304956 TI - Calcified tissues. PMID- 4304957 TI - Preliminary characterization of some ectopic hormones. PMID- 4304959 TI - [Hepatography by intrasplenic injection of oily contrast medium (ultra-fluid lipiodol): its value in the diagnosis of intraphepatic tumor formations]. PMID- 4304960 TI - [Arteriography of primary tumors of the liver]. PMID- 4304958 TI - The hormonal regulation of glycogen metabolism in muscle. PMID- 4304961 TI - Effect of corticotrophin therapy on pituitary-adrenal function. PMID- 4304962 TI - [Epidemiological aspects of myxovirus para-influenzae infections. Serological investigation carried out on 170 sera in the East of France]. PMID- 4304963 TI - [Study and interpretation of giant and multinucleated Entamoeba histolytica observed in culture]. PMID- 4304964 TI - [Medicamentous therapy within the scope of electrotherapy for arrhythmias]. PMID- 4304965 TI - [Influencing the endometrium and vaginal epithelium through the administration of conjugated estrogenic substances in combination with a psychopharmacologic agent]. PMID- 4304967 TI - [Clinical evolution and chromosome study of a case of Albright's syndrome]. PMID- 4304966 TI - [On a case of resuscitation in the Zanoli-Vecchi postoperative convulsive syndrome]. PMID- 4304968 TI - [Fetal and congenital cytomegalic disease. Significance of prenatal incubation period]. PMID- 4304969 TI - [Fetal poisonings and endocrine complications]. PMID- 4304970 TI - [Occuet congenital cytomegalic disease. A contribution to its diagnosis]. PMID- 4304971 TI - [Diagnostic nerve tissue biopsies]. PMID- 4304972 TI - [Osteopathies in antiepileptic long-term therapy (preliminary report)]. PMID- 4304973 TI - [On anasarca]. PMID- 4304974 TI - [The importance of chemotherapeutic agents in the treatment of malignant trophoblastic tumors]. PMID- 4304976 TI - Effect of hormones on the growth of virus-transformed hamster prostatic tissue. PMID- 4304975 TI - [Systemic and regional hemodynamics during treatment with angiotensin]. PMID- 4304977 TI - Rejection of skin isografts from donors with leukemia. PMID- 4304978 TI - [The effect of antibacterial preparations on the activity of succinate dehydrogenase ancytochrome oxidase in the tissue of guinea pigs in experimental tuberculosis]. PMID- 4304979 TI - [Virologic survey of sewage in the city of Bydgoszcz. I]. PMID- 4304980 TI - [Studies of river water sewage and water supply in the city of Poznan for presence of cytopathogenic viruses]. PMID- 4304981 TI - [The effects of estrone on myomatous cells and the surrounding myometrium in tissue culture]. PMID- 4304982 TI - [Changes in mitochondrial enzymes at protein depletion]. PMID- 4304983 TI - [Karyotype and histologic changes in anomalous gonadal development in man. II. True hermaphroditism]. PMID- 4304984 TI - [Bilateral thecoma of the ovary with carcinomatous evolution]. PMID- 4304985 TI - Purification and properties of 5-phosphoribosyl pyrophosphate amidotransferase from adenocarcinoma 755 cells. PMID- 4304986 TI - Energy-linked reactions in photosynthetic bacteria. 3. Further studies on energy linked nicotinamide-adenine dinucleotide reduction by Rhodospirillum rubrum chromatophores. PMID- 4304987 TI - Promitochondria of anaerobicallly grown yeast. II. Lipid composition. PMID- 4304989 TI - Electron paramagnetic resonance studies of nitric oxide hemoglobin derivatives. I. Human hemoglobin subunits. PMID- 4304988 TI - Rate of isotope exchange in enzyme-catalyzed reactions. PMID- 4304990 TI - Synthesis of acetylcholine in the electric organ of Torpedo. PMID- 4304991 TI - A comparative study on the phosphoglyceric acid cycle in mammalian erythrocytes. PMID- 4304992 TI - Molt cycle regulation of nucleotide pyrophosphatase in the hepatopancreas of the blue crab, Callinectes sapidus Rathbun. PMID- 4304993 TI - Cytochrome oxidase-succinic dehydrogenase activities and the melanin pigment cycle in poikilothermic vertebrates. PMID- 4304994 TI - The effect of starvation, feeding, glucose and ACTH on the liver glycogen levels of Tilapia mossambica. PMID- 4304995 TI - Effect of propranolol and phentolamine on canine and bovine responses to TSH. PMID- 4304996 TI - In vivo and in vitro studies of steroid production by a luteoma and an adrenal cortical carcinoma in mice. PMID- 4304997 TI - Effects of adrenocorticotropic hormone on rat adrenal corticosteroidogenesis in vivo. PMID- 4304998 TI - Failure of theophylline to potentiate stimulated thyroidal glucose oxidation and phospholipogenesis. PMID- 4304999 TI - Effects of theophylline, prostaglandin E-1 and adrenergic blocking agents on TSH stimulation of thyroid intermediary metabolism. PMID- 4305000 TI - Effects of adrenal cortical hormones and thyroxine on phosphorylase activity in muscle. PMID- 4305002 TI - Effect of glucagon, adenosine-3',5'-monophosphate and theophylline on free fatty acid release by rat liver slices and on tissue levels of coenzyme A esters. PMID- 4305001 TI - Adrenal cells in tissue culture. II. Steroidogenic responses to nucleosides and nucleotides. PMID- 4305003 TI - Relation of the pituitary to the sodium-retaining effects of adrenal enucleation. PMID- 4305004 TI - Preparation of 16-alpha-hydroxypregnenolone-3-sulfate and a study of its anomalous behavior during hydrolysis. PMID- 4305005 TI - Interruption of pregnancy in the rat by administration of ACTH. PMID- 4305006 TI - Adenyl cyclase activity in the rabbit ovary. PMID- 4305007 TI - Protein fluorescence and inactivation of glutamate dehydrogenases during treatment with silver. PMID- 4305008 TI - Insomnia following parachlorophenylalanine in the rat. PMID- 4305009 TI - Effects of angiotensin--II on coronary smooth muscle. PMID- 4305010 TI - Isolation of human leukocyte granules using colloidal silica-polysaccharide density gradients. PMID- 4305011 TI - The primary structure of valine-I transfer ribonucleic acid from Torulopsis utilis. I. Complete digestion with pancreatic ribonuclease and ribonuclease T1. PMID- 4305013 TI - Biochemical and morphological characterization of microvilli isolated from intestinal mucosal cells. PMID- 4305012 TI - Enzyme distribution in subcellular fractions of intestinal mucosal cells. PMID- 4305014 TI - ESR study of L-alanine-1-13C irradiated at low temperatures. PMID- 4305015 TI - Note on the aetiology of acute laryngotracheobronchitis in children. Findings in the autumn of 1965 and the spring of 1966. PMID- 4305016 TI - Degradation of cytosin-containing bacterial and bacteriophage DNA after infection of Escherichia coli B with bacteriophage T4D wild type and with mutants defective in genes 46, 47 and 56. PMID- 4305017 TI - Antitumor immunity in the Shope papilloma-carcinoma complex. IV. Search for a transmissible factor increasing the frequency of tumor regression. PMID- 4305018 TI - Cytomegaloviruses as common adventitious contaminants in primary African green monkey kidney cell cultures. PMID- 4305020 TI - Adrenocortical responsiveness in patients with renal transplants receiving prednisone. PMID- 4305019 TI - [Effect of inhalation anesthetics on paradoxical sleep]. PMID- 4305021 TI - Liver disease, renal function, and the renin-angiotensin system. PMID- 4305022 TI - Identification of purine ribosidase in the glioblastoma. PMID- 4305023 TI - Surgical treatment of amebiasis. PMID- 4305024 TI - Local and topical anesthetics in ophthalmology. PMID- 4305025 TI - Renal cell carcinoma in children. Report of two cases. PMID- 4305026 TI - Estimation of renin activity in human amniotic fluid of normal and toxemic pregnant women. PMID- 4305027 TI - The activation of virus synthesis in polyoma-transformed cells. PMID- 4305028 TI - Viropexis of herpes simplex virus by HeLa cells. PMID- 4305029 TI - Studies of avian leukosis group-specific complement-fixing serum antibodies in pigeons. PMID- 4305030 TI - Isolation of viruses using specific immunoadsorbents. PMID- 4305031 TI - [Submicroscopic demonstration of phosphorylase in skeletal muscle of the guinea pig following infection with the virus of foot-and-mouth disease]. PMID- 4305032 TI - [Serum antibodies against Adenoviruses, Reoviruses and Coxiella burnetii in subjects of Swat (northwestern Pakistan)]. PMID- 4305033 TI - [Detection of hemagglutination-inhibiting antibodies against measles virus and mumps virus and complement-fixing antibodies against the respiratory syncytial virus in subjects of Swat (northwestern Pakistan)]. PMID- 4305034 TI - [Galactose-induced pancreatic dystrophy and pancreatitis. Histological, histochemical, and electron microscopic studies]. PMID- 4305036 TI - E.P.R. absorption by the vapour phase of cigarette smoke, condensed and examined at low temperatures. PMID- 4305035 TI - [New method of study of substances active on neuromuscular transmission]. PMID- 4305037 TI - [On the technic of intrauterine transfusion in Rh incompatibility by means of surface demonstration with lipiodol-ultrafluid]. PMID- 4305038 TI - [Studies on additional Iscador therapy in the management of women with surgically and radiotherapeutically treated genital carcinoma]. PMID- 4305040 TI - Carbenicillin and Pseudomonas aeruginosa infection of burns. PMID- 4305039 TI - [Enzyme content of Hofbauer cells in the human placenta and its functional significance]. PMID- 4305041 TI - Polyamide-silica gel thin-layer chromatography of red food dyes. PMID- 4305042 TI - Use of a liquid chromatograph in lipid class separation. PMID- 4305043 TI - [The separation of tomatidenol, solasodine and soladulcidine and yamogenin, diosgenin and tigogenin by thin-layer chromatography]. PMID- 4305044 TI - Enzyme diversion applied to the kinetic estimation of glucose-6-phosphatase activity. PMID- 4305045 TI - Relationship between adipose lipoprotein lipase activity and compounds which affect intracellular lipolysis. PMID- 4305047 TI - [On the life cycle of Entamoeba histolytica]. PMID- 4305046 TI - [On the mechanism of antiamoebal effect of monomycin]. PMID- 4305048 TI - [A case of giant seminoma treated surgically with 5-year favorable results]. PMID- 4305049 TI - [The effect of cytochrome c on postischemic kidney failure]. PMID- 4305050 TI - [Hypophosphatasia in children]. PMID- 4305051 TI - [Contract roengenography in the diagnosis of patency of the eustachian tubes]. PMID- 4305052 TI - [Virilizing tumors of the adrenal glands in girls]. PMID- 4305053 TI - [Videin D3 in the prevention of rickets in premature children]. PMID- 4305055 TI - [The Guillain-Barre-Syndrome in children]. PMID- 4305054 TI - [Use of a complex of low-molecular substances to speed up acclimatization to hypoxia]. PMID- 4305056 TI - [Cockayne's syndrome]. PMID- 4305057 TI - Myocardial function in patients with coronary artery disease. PMID- 4305058 TI - Chemodectoma of an aortic body. PMID- 4305059 TI - Primary cystic carcinoma of the liver. PMID- 4305060 TI - [Cytogenetics of Mus (Leggada) minutoides musculoides Temm. and similar forms. Study of a population of the Ivory Coast]. PMID- 4305061 TI - Transient neurologic complication of positive contrast orbitography. PMID- 4305062 TI - Recurrent herpes simplex conjunctival ulceration. PMID- 4305063 TI - Synovial collagenase: its presence in culture from joint disease of diverse etiology. PMID- 4305064 TI - Enzymatic synthesis of oligoguanylic acids containing 2'-5' phosphodiester linkages. PMID- 4305065 TI - The ability of reduced nicotinamide mononucleotide to function as a hydrogen donor in the glutamic dehydrogenase reaction. PMID- 4305066 TI - Two distinct transfer enzymes from rabbit reticulocytes with ribosome dependent guanosine triphosphate phosphohydrolase activity. PMID- 4305067 TI - The structure of an NAD-pyruvate complex. PMID- 4305068 TI - [On several tests of the value of saponin used alone as an adjuvant in the preparation of foot-and-mouth disease vaccine]. PMID- 4305069 TI - The structure of a free radical produced from questiomycin A. Photochemistry of antibiotics. II. PMID- 4305070 TI - Intranuclear crystal formation of poliovirus: electron microscopic observations. PMID- 4305072 TI - [Studies of the virus in feces and of the changes in antibody movement in patients with Heine-Medin disease hospitalized from 1960 to 1966]. PMID- 4305071 TI - [On a case of herpetic superinfection]. PMID- 4305073 TI - Febrile infectious mononucleosis-like syndrome following splenectomy: an example of post-transfusion mononucleosis. PMID- 4305074 TI - Orthocresyl phosphate neuropathy: report of an outbreak in Fiji. PMID- 4305075 TI - Radiation effects on cold-induced growth response of interscapular brown fat. PMID- 4305076 TI - Toward control of viral infections of man. PMID- 4305077 TI - Glucagon-sensitive adenyl cylase in plasma membrane of hepatic parenchymal cells. AB - The plasma membrane of hepatic parenchymal cells contains an adenyl cyclase system that is stimulated by glucagon. Adrenocorticotropin and epinephrine do not stimulate this adenyl cyclase, and very little cyclic phospho-diesterase activity is present in the membrane. These findings support the concept that glucagon exerts its regulatory action in the liver by stimulating adenyl cyclase activity in the plasma membrane. PMID- 4305078 TI - Hallucinogen-tranquilizer interaction: its nature. AB - Study of the competition between hallucinogens and tranquilizers at cerebral synapses and on behavior in various species of animals indicates a continuum of effects from protection to dominance of tranquilizer toxicity as the dose of tranquilizer increases. Data on cat and monkey behavior, supplementing that on the rat, show that it is possible to arrive at a tranquilizer dose that can aggravate instead of protect, in accord with the competitive inhibitory nature of the interaction of hallucinogen and tranquilizer. PMID- 4305079 TI - [Contribution on the choice of parameters in a biological model]. PMID- 4305080 TI - Some problems in the estimation of localized activity. PMID- 4305081 TI - [Clinical, laboratory diagnostic, electrophonocardiographic, and roentgenologic studies with consideration of the ACTH test in Moller-Barlow's disease and acropachy of the dog. I. Moller-Barlow's disease]. PMID- 4305082 TI - A bacterial factor capable of solubilizing cholinesterase from plaice body muscle. PMID- 4305083 TI - Basic studies on the mechanism of action of vitamin D. PMID- 4305084 TI - 25-Hydroxycholecalciferol, the probable metabolically active form of vitamin D. Isolation, identification, and subcellular location. PMID- 4305085 TI - Absorption of vitamin D3 oleate in the rat. PMID- 4305086 TI - Vitamin D-induced calcium-binding protein of intestinal mucosa. Relation to vitamin D dose level and lag period. PMID- 4305087 TI - Absorption and metabolism of vitamin D3 in man. PMID- 4305088 TI - Amebic abscess of the liver. Experience with 15 cases in 3 and one-half years in California. PMID- 4305089 TI - Non-staphylococcal pseudomembranous colitis. PMID- 4305090 TI - Determination of free hydrogen cyanide in river water by a solvent-extraction method. PMID- 4305092 TI - Twitch, tetanus and posttetanic potentiation as indices of nerve-muscle block in man. PMID- 4305091 TI - Neurologic complications following spinal anesthesia with lidocaine: a prospective review of 10,440 cases. PMID- 4305093 TI - The effects of small incremental doses of d-tubocurarine on neuromuscular transmission in anesthetized man. PMID- 4305094 TI - Biochemical changes in rat liver in response to treatment with drugs and other agents. I. Effects of anticonvulsant, anti-inflammatory, hypocholesterolaemic and adrenergic beta-blocking agents. PMID- 4305095 TI - Biochemical changes in rat liver in response to treatment with drugs and other agents. II. Effects of halothane, DDT, other chlorinated hydrocarbons, thioacetamide, dimethylnitrosamine and ethionine. PMID- 4305096 TI - The influence of oligomycin on the actions of epinephrine and theophylline upon the perfused rat heart. PMID- 4305097 TI - Acetaldehyde--an inhibitor of the enzymatic oxidation of 5 hydroxyindoleacetaldehyde. PMID- 4305099 TI - The hydroxyproline of elastin. PMID- 4305098 TI - On a relationship between ion transport and thiamine in nervous tissue. PMID- 4305100 TI - The mechanism of binding of flavin-adenine dinucleotide to the apoenzyme of glucose oxidase and evidence for the involvement of multiple bonds. PMID- 4305102 TI - The structural basis of the catalytic function of staphylococcal nuclease. PMID- 4305101 TI - Determination of melting sequences in DNA and DNA-protein complexes by difference spectra. AB - A graphical formula is presented for determining the base ratio of melted DNA. By use of this formula, the composition of sequences which melt in different portions of the melting curves of Clostridium DNA, Escherichia coli DNA, and mouse DNA were determined. As the DNA melts, the per cent of adenine and thymine (AT) in the melted sequences decreases linearly with temperature. The average composition of sequences which melt in a given part of the melting curve is proportional to the base ratio of the DNA. The concentration and average composition of sequences were determined for three parts of the melting curves of the DNA samples, and a frequency distribution curve was constructed. The curve is symmetrical and has a maximum at about 56% AT. The distribution of GC-rich sequences on the E. coli chromosome was estimated by shearing, partially melting, and fractionating the DNA on hydroxylapatite. GC-rich sequences appear to occur every thousand base pairs, and have a maximum length of about 180 base pairs. The graphical formula was applied to the determination of the composition of sequences which melt in different parts of the melting curve of chromatin. Throughout the melting curve, the composition of the melting sequences is about 60% AT, which appears to suggest that relatively long sequences are melting simultaneously. Their melting temperature may be a function of the composition of the protein on different parts of the DNA. The problem of light scattering in DNA protein and DNA was also investigated. A formula is presented which corrects for light scattering by relating the intensity of the scattered light to the rate of change of absorbance of DNA with wavelength. PMID- 4305103 TI - The relationship between Mg2+-stimulated ATPase activity and glycogen content in rat liver. PMID- 4305105 TI - Fine structure of glomus tumor: similarity of glomus cells to smooth muscle. PMID- 4305106 TI - Chemodectoma of the orbit. PMID- 4305104 TI - Microradiographic investigations of calcifications of the female breast. PMID- 4305108 TI - Action of the venom of Microbracon hebetor Say on larvae and adults of Philosamia cynthia Hubn. PMID- 4305107 TI - Evaluation of a high dose cyclophosphamide regimen in childhood tumors. PMID- 4305109 TI - Concomitant neoplasia in the liver of a hen. PMID- 4305110 TI - Reovirus-specific, single-stranded RNA's synthesized in vitro with enzyme purified from reovirus-infected cells. PMID- 4305111 TI - Peripheral neuropathies. PMID- 4305113 TI - Stomach cancer associated with carcinoid tumor of rectum. PMID- 4305112 TI - Note on the uptake of serotonin by subcellular granules of brain. PMID- 4305114 TI - Pathological study of metastatic involvements of the stomach cancers. I. PMID- 4305115 TI - [Autopsy case of cancer of the gastric mucosa with rapid wide-spread metastases]. PMID- 4305116 TI - Role of haemichromes in the formation of inclusion bodies in haemoglobin H disease. PMID- 4305117 TI - Selective inhibition of vaccinia virus by the antibiotic rifampicin. PMID- 4305118 TI - Proinsulin and the biosynthesis of insulin. PMID- 4305119 TI - Androgen studies in a patient with lipoid-cell tumor of the ovary. PMID- 4305120 TI - The neuromuscular system and the re-education of movement. PMID- 4305121 TI - Granular cell myoblastoma of the eye. Case report. PMID- 4305123 TI - Sodium excretion in obese adolescents. PMID- 4305122 TI - Studies of plasma renin activity in patients with hypertension. PMID- 4305124 TI - Some renal histochemical lesions in rats chronically poisoned with carbon tetrachloride. PMID- 4305125 TI - Oculomotor control: a possible function of rem sleep. PMID- 4305126 TI - [Nasal cylindroma with rapid and fatal evolution in a 1-year-old infant]. PMID- 4305127 TI - Adsorption of bacterial alpha-amylase on quartz and denaturation of adsorbed enzyme by shaking. PMID- 4305128 TI - [Comparative study of 2 different types of hormone therapy in dysmenorrhea]. PMID- 4305129 TI - [Effect of beta rays on neural transmission in the isolated rat cervical sympathetic ganglion]. PMID- 4305131 TI - [Various observations on the character of development of mixed tumors of the salivary glands]. PMID- 4305132 TI - [Angioma and telangiectasia in scleroderma (apropos of 5 cases of the so-called C.R.S.T. syndrome)]. PMID- 4305130 TI - [Influence of diphosphonates on the deposition and dissolution ofccalcium phosphate in vitro and in vivo]. PMID- 4305133 TI - [Bronchoscopic diagnosis of a benign tumor (cylindroma) obstructing the orifice of the left main trunk. Treatment by bronchotomy, curettage, completed by a left inferior lobectomy. Commentary]. PMID- 4305134 TI - [Actinophage of lysogenic culture Proactinomyces (Nocardia) fructiferi, producer of the antibiotic ristomycin]. PMID- 4305135 TI - [On a case of exudative enteropathy]. PMID- 4305136 TI - [An unusual cause of unilateral exophthalmos in a child]. PMID- 4305137 TI - [An enzyme-histochemical study of the action mechanism of Solcoseryl on epithelisation]. PMID- 4305138 TI - [Cytodiagnosis in lung diseases. Its importance and its value. A study of 945 cases]. PMID- 4305139 TI - [Does the recent knowledge on the renin-angiotensin system have clinical applications?]. PMID- 4305141 TI - [On the problem of pulmonary adenomatosis]. PMID- 4305140 TI - [Intravital diagnosis of pulmonary adenomatosis in a patient]. PMID- 4305142 TI - [Follow-up care of discharged transverse paraplegia patients]. PMID- 4305143 TI - [On some antigens in cells of Seidel's ascitic hepatoma]. PMID- 4305144 TI - [Generalized cytomegaly]. PMID- 4305145 TI - [The effect of ACTH and glucocorticoids on the phagocytic activity of leukocytes and cells of the reticuloendothelial system (review of the literature)]. PMID- 4305146 TI - [Rapid diagnosis of respiratory virus infections]. PMID- 4305147 TI - [Detection of a new specific antigen in cells infected with myxoviruses]. PMID- 4305148 TI - [Transformation of cultures of monkey embryonic tissue by the Carr-Zil'ber strain of Rous virus]. PMID- 4305149 TI - [Physico-chemical differences in antibodies to arboviruses at various periods of time after single immunization of animals]. PMID- 4305150 TI - [On the resistance of chick embryos to Rous sarcoma virus]. PMID- 4305152 TI - Sporadic aniridia and Wilms' tumor. PMID- 4305153 TI - ATP dependent conformational change in "spin labelled" sarcoplasmic reticulum. PMID- 4305151 TI - [The effects of the host's nutrition on the development of parasitic protozoa]. PMID- 4305154 TI - The incorporation of p-hydroxybenzoate and isopentenyl pyrophosphate into polyprenylphenol precursors of ubiquinone by broken cell preparations of Rhodospirillum rubrum. PMID- 4305155 TI - Studies on oxidative phosphorylation. XVII. Physical and chemical properties of factor B. PMID- 4305156 TI - Studies on ultrastructural dislocations in mitochondria. II. On the dislocation induced by lyophilization and the mechanism of uncoupling. PMID- 4305157 TI - Isolation of chitin and glucan from the cell wall of the yeast form of Paracoccidioides brasiliensis. PMID- 4305158 TI - Glycerolphosphate oxidoreductases and the glycerophosphate cycle in ehrlich ascites tumor cells. PMID- 4305159 TI - The biogenesis of mitochondria. IX. Formation of the soluble mitochondrial enzymes malate dehydrogenase and fumarase in Saccharomyces cerevisiae. PMID- 4305160 TI - The copper catalyzed oxidation of cysteine to cystine. PMID- 4305161 TI - Horse muscle acyl phosphatase: purification and some properties. PMID- 4305163 TI - Studies on epsilon-prototoxin of Clostridium perfringens type D. I. Purification methods: evidence for multiple forms of epsilon-prototoxin. PMID- 4305162 TI - Structural basis of group G streptococcal antigenicity. PMID- 4305165 TI - Studies of gluconeogenic mitochondrial enzymes. 3. The conversion of alpha ketoglutarate to glutamate by bovine liver mitochondrial glutamate dehydrogenase and glutamate-oxaloacetate transaminase. PMID- 4305164 TI - Studies on gluconeogenic mitochondrial enzymes. II. The conversion of glutamate to alpha-ketoglutarate by bovine liver mitochondrial glutamate dehydrogenase and glutamate-oxaloacetate transaminase. PMID- 4305166 TI - Studies of gluconeogenic mitochondrial enzymes. IV. The conversion of oxaloacetate to fumarate by bovine liver mitochondrial malate dehydrogenase and fumarase. PMID- 4305167 TI - Energy conversion-linked changes of carotenoid absorbance in Rhodospirillum rubrum chromatophores. PMID- 4305168 TI - Effect of exercise on alpha-glycerophosphate dehydrogenase activity in skeletal muscle. PMID- 4305169 TI - On the site of discrimination of chicks against vitamin D. PMID- 4305170 TI - The enzymic synthesis of O-alpha-D-glucopyranosyl (1-6)-2-amino-2-deoxy-D glucopyranose and its N-acetyl derivative. PMID- 4305171 TI - Surgical management of cervical paragangliomata. PMID- 4305172 TI - Effect of cortisone and corticotropin on gastric secretion and peptic ulceration in the dog. PMID- 4305173 TI - Granular cell myoblastoma of the breast. PMID- 4305174 TI - [Pregnancy following left-sided lobectomy of the liver during recurring hepatoma]. PMID- 4305175 TI - [A case of oral gas gangrene poisoning with fatal outcome]. PMID- 4305176 TI - Effect of collagenase on the behaviour of cells from young and old donors in culture. PMID- 4305178 TI - Intrinsic and extrinsic factors of molecular ageing. PMID- 4305177 TI - Gas chromatographic analysis of urinary 17-ketosteroids response to gonadotrophin and ACTH in young and old persons. PMID- 4305179 TI - [The influence of dowtherm A on some hematologic and biochemical parameters in rats]. PMID- 4305180 TI - Further implication of murine leukemia-like virs in the disorders of NZB mice. AB - Further evidence implicating murine leukemia-like virus in the disorders of NZB mice was afforded by a study of antigens associated with murine leukemia virus (MuLV). MuLV group antigens were prevalent in extracts of spleen, kidney, and, to a lesser extent, thymus throughout a substantial portion of the life span of NZB mice as well as in extracts of lymphomas and sarcomas indigenous to the strain. G (Gross) soluble antigen, type-specific antigen, was first detected in plasma of untreated NZB mice at 3 months of age. G soluble antigen production increased thereafter in line with age, with 50% of reactions becoming positive at 5.3 months and 100% at 7 to 9 months. From months 3 to 9, the time-response curve for positive conversion of direct antiglobulin (Coombs) tests in untreated NZB mice corresponded closely to that for G soluble antigen production. Beyond the 9th month, G soluble antigen underwent elimination from the plasma of NZB mice, with positive reactions reduced to 50% at 13.3 months and to 0% at 18 months. G natural antibody was first detected in the serum of NZB mice at about 10 months of age and increased thereafter in line with age. The curves for G antibody production and G soluble antigen elimination bore a reciprocal relation to each other with crossover at 50% response occurring at 13.3 months. Significant proteinuria, a functional manifestation of membranous glomerulonephritis, became increasingly prevalent in female NZB mice as G soluble antigen was eliminated from plasma. Cumulative mortality of female NZB mice, mainly attributable to renal glomerular disease, increased in phase with G antibody production. MuLV group antigens were identified in the glomerular lesions by the immunofluorescence method. Positive conversion of direct antiglobulin tests was significantly delayed by vaccinating baby NZB mice with formaldehyde-inactivated cell-free filtrates of older NZB mouse spleens. The plasmas of vaccinated NZB mice with negative direct antiglobulin reactions at 4 to 7 months were likewise negative when tested for G soluble antigen. The 50% response time for G antibody production in the vaccinated NZB mice occurred at 7.3 months, that is, 6 months earlier than in untreated NZB mice. The collective findings implicate murine leukemia-like virus in the etiology of autoimmune hemolytic disease and membranous glomerulonephritis, as well as malignant lymphoma, of NZB mice and suggest that virus-specified cell-surface and soluble antigen is a factor in the immunopathogenesis of the renal disease and possibly also the autoimmune hemolytic disease. PMID- 4305181 TI - [Electron microscope and histocytochemical studies of human placental villi]. PMID- 4305182 TI - Peripheral dysostosis: investigation of metabolic and endocrine functions. PMID- 4305183 TI - A case of Bartter's syndrome with abnormal renin response to salt load. PMID- 4305184 TI - Congenital cytomegalovirus infection associated with low birth weight. PMID- 4305185 TI - Rhinovirus infections in nursery school children. PMID- 4305186 TI - Plasma renin in Bartter's syndrome: response of depression of stimuli for renin release. PMID- 4305187 TI - A case of glycogen storage disease. PMID- 4305188 TI - Metabolism and serum protein binding of 3H-vitamin D4 in vitamin D-resistant rickets. PMID- 4305189 TI - Growth in familial hypophosphatemic vitamin D-resistant rickets. PMID- 4305190 TI - Further experience in treatment of juvenile nasopharyngeal angiofibroma. PMID- 4305191 TI - [Systolic liver sounds in primary liver carcinoma]. PMID- 4305192 TI - [Management of climacteric disorders using a new combination drug Menrium]. PMID- 4305193 TI - Here today--gone today. PMID- 4305194 TI - [Cerebral blood circulation. Indications and surgical technics]. PMID- 4305195 TI - [On a case of survival after acute poisoning by a mixture of hydrogen sulfide and hydrocyanic acid]. PMID- 4305196 TI - [Characteristics of the ovarian-adrenal reaction to extreme influences]. PMID- 4305197 TI - An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine. PMID- 4305198 TI - Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine. PMID- 4305199 TI - Respiratory virus immunization. I. A field trial of two inactivated respiratory virus vaccines; an aqueous trivalent parainfluenza virus vaccine and an alum precipitated respiratory syncytial virus vaccine. PMID- 4305200 TI - Field evaluation of a respiratory syncytial virus vaccine and a trivalent parainfluenza virus vaccine in a pediatric population. PMID- 4305201 TI - Epidemiologic studies of latent virus infections in captive monkeys and baboons. I. Overall plans and virus isolations with special reference to SV40 and foamy viruses. PMID- 4305202 TI - Epidemiologic studies of latent virus infections in captive monkeys and baboons. II. Serologic evidence of myxovirus infections with special reference to SV5. PMID- 4305203 TI - Experimental infection of monkeys with Langat virus. 3. Infection produced by virus feeding. PMID- 4305204 TI - [On the angiotensinase activity of the kidney of the rat]. PMID- 4305205 TI - [On the angiotensinase activity of rat brain homogenates]. PMID- 4305206 TI - [On the angiotensinase activity of rat liver homogenates]. PMID- 4305207 TI - [Action of some hormones (insulin, STH, TSH, FSH, LH) on the angiotensinase of human erythrocytes in vitro]. PMID- 4305208 TI - [Biochemical changes in the brain of the chick embryo caused by Newcastle disease virus]. PMID- 4305209 TI - [Anthocyanin glycosides and oxidation of retinol in the presence of NAD]. PMID- 4305210 TI - [Analysis of the protective power of the polyoma virus irradiated by ultra-violet rays against the transplanted polyoma tumor]. PMID- 4305211 TI - [Enzyme activity of rat fibroblasts cultivated in vitro. Cytoenzymologic study]. PMID- 4305212 TI - [Analysis of the constituent phospholipids in the yeasts Endomycetales, Cryptococcaceae and Sporobolomyces]. PMID- 4305213 TI - [On 2 cases of mixed tumor of the palate]. PMID- 4305214 TI - [Incidence of infection with respiratory syncytial virus in undifferentiated acute respiratory diseases]. PMID- 4305215 TI - [Pre-hispanic Mexican pediatrics]. PMID- 4305216 TI - Disseminated herpes simplex in a newborn. A consequence of infection in the mother. PMID- 4305217 TI - [Poliomyelitis immunization]. PMID- 4305218 TI - [On the problem of revaccination against poliomyelitis. Results of a reinfection experiment using the poliovirus type 1, strain "LSc, 2ab (Sabin)". 4 and half years following original vaccination]. PMID- 4305219 TI - [Lobar pneumonia caused by Pseudomonas aeruginosa]. PMID- 4305220 TI - [Malignant struma. Surgical experience report]. PMID- 4305221 TI - [Pharmacology of some vasoactive agents]. PMID- 4305222 TI - [Isolation and properties of Nitrosomonas europaea cytochrome c]. PMID- 4305223 TI - [Epidemiological significance of the presence of anti-influenza and anti adenovirosis antibodies in the mother and newborn infant]. PMID- 4305224 TI - [Clinico-etiological study of an epidemic of adenovirus infection appearing in a closed community of children]. PMID- 4305225 TI - [Cystic arachnoiditis and adenovirus infection]. PMID- 4305226 TI - Drugs and sleep. PMID- 4305227 TI - Hypothalamic pituitary stimulating and inhibiting hormones. PMID- 4305228 TI - [The detection of intracranial tumours by ultrasonic tomography (preliminary results obtained in adults by using an experimental device)]. PMID- 4305229 TI - [Varicellar pneumopathy. Apropos of an observation]. PMID- 4305230 TI - [The survival and multiplication of Cl. perfringens in food products]. PMID- 4305231 TI - [On the epidemiology of reovirus infections in children's collectives]. PMID- 4305232 TI - [The role of Cl. perfringens lecithinase in the effect of the toxin on tissue cultures]. PMID- 4305233 TI - [Observations on the radioprotective effect of the adenosine triphosphate- diphosphopyridine nucleotide association. Research with the use of Fe59]. PMID- 4305234 TI - An electron cytochemical demonstration and biochemical analysis of adenosine triphosphatase activity in cancer cell plasma membrane. PMID- 4305235 TI - [Considerations on 2 cases of mixed tumors of the minor salivary glands]. PMID- 4305237 TI - [Scanning of brain tumors. Observations on 101 cases]. PMID- 4305236 TI - [Research on phosphatases of the mouse placenta. Hydrolysis of steroid phosphates]. PMID- 4305238 TI - [Contribution to odontodysplasia]. PMID- 4305239 TI - [Mechanism of restoration of adrenergic transmitter stores after their ex- haustion in axonal endings]. PMID- 4305240 TI - [On the mechanism responsible for prolonged contralateral influences in the spinal cord on exposure to single stimuli]. PMID- 4305241 TI - [Influence of dorsal root section on mono- and polysnyaptic spinal reflexes]. PMID- 4305242 TI - [Functional and biochemical changes in cardiac muscle with experimental training]. PMID- 4305243 TI - [Role of the vagus and splanchnic nerves in transmission of hypothalmic influences on gastric secretion]. PMID- 4305245 TI - Neutralization of the anticomplementary activity of an amorphous silica by some proteins. PMID- 4305244 TI - [Studies on glucose-6-phosphatase in the liver and kidney, IV. Role of the pituitary-adrenal system in experimental diabetics]. PMID- 4305246 TI - [The acid soluble erythrocyte nucleotides in hereditary spherocytosis. Studies on 3 family groups]. PMID- 4305247 TI - Formation of thymyl radicals in gamma-irradiated frozen aqueous systems: as E.S.R. study. PMID- 4305249 TI - Control of renin secretion in the anesthetized dog. 1. Relationship between renin secretion and plasma sodium concentration in the peritoneal dialyzed dog. PMID- 4305248 TI - Liver enzyme histochemistry: a comparative study of sheep, calf and rat. PMID- 4305250 TI - [Changes in enzyme levels of the serum and liver tissue in experimental hypoxia of the liver]. PMID- 4305252 TI - [Results following Billroth I]. PMID- 4305251 TI - [Data from experimental study of strains of Entamoeba histolytica recovered from patients with amoebiasis and from healthy carriers]. PMID- 4305253 TI - [Viscosity measurement on aqueous Aerosil-dispersion with the Brookfield synchro lectric viscosimeter]. PMID- 4305254 TI - The role of the adrenals in changes of liver triglycerides content after partial hepatectomy in rats of different ages. PMID- 4305255 TI - [Renin--facts and hypotheses]. PMID- 4305256 TI - [C cells of the normal human thyroid]. PMID- 4305257 TI - [Present state of the dynamic studies of the adrenal cortex (excepting and aldosterone function)]. PMID- 4305258 TI - [Psychotropic drugs]. PMID- 4305259 TI - [Some problems of a dispensary after-treatment of children recovering from epidemic hepatitis]. PMID- 4305260 TI - [Biosynthesis of nicotinic acid in lemurs of the Macaca rhesus species]. PMID- 4305261 TI - [Influence of phosphorus-rich diets containing different amounts of fat and vitamin D on the osteogenesis in growing albino rats]. PMID- 4305262 TI - [Biological activity of plant polyphenols]. PMID- 4305263 TI - Anti-I agglutinins in non-human sera. PMID- 4305264 TI - [The functional status of the brain in hormonal therapy of patients with bronchial asthma]. PMID- 4305265 TI - [Characteristics of ischemic disorders of nerve trunks in obliterative endarteritis]. PMID- 4305266 TI - [A case of bronchiolar cancer simulating pleural mesothelioma]. PMID- 4305267 TI - Hypovolemic shock: microcirculatory changes during and after specific therapy. PMID- 4305268 TI - Islet cell tumors and hypoglycemia. PMID- 4305269 TI - [On the sensitivity of microflora of burn wounds to antibiotics]. PMID- 4305270 TI - Activation and inhibition of purified phosphotransacetylase of Escherichia coli B by pyruvate and by NADH2 and certain nucleotides. PMID- 4305271 TI - Clostridium perfringens polynucleotide phosphorylase: interconversion of heavy and light molecular weight species. PMID- 4305272 TI - Inhibition of beta-D-galactosidases by D-galactal. PMID- 4305273 TI - Tryptophan-mediated substrate inhibition of anthranilate-5 phosphoribosylpyrophosphate phosphoribosyltransferase. PMID- 4305274 TI - Thymidine salvage pathway in normal and leukemic leukocytes with effects of ATP on enzyme control. PMID- 4305275 TI - [Experimental shock caused by silica and its prevention with heparin]. PMID- 4305276 TI - [Effects of total sympathectomy on hemodynamic changes in desynchronized sleep]. PMID- 4305277 TI - [Regional hemodynamics during desynchronized sleep in the cat]. PMID- 4305278 TI - Hormones in human pituitary sinusoid blood: concentration of LH, GH and TSH. PMID- 4305279 TI - Cytomegalic adrenocortical hypoplasia and increased plasma 20-alpha-hydrozypregn 4-en-3-one in a man exhibiting the features of selective mineralocorticoid deficiency. PMID- 4305280 TI - Comparison of the effect of ACTH and an inhibitor of 3-beta-hydroxysteroid dehydrogenase on the synthesis of adrenal microsomal proteins. PMID- 4305281 TI - Compounds which stabilize and organize the tetrameric isozymes of lactate dehydrogenase. PMID- 4305282 TI - Determination of corticosteroid-binding proteins by an adsorption method. PMID- 4305284 TI - [A benign tumor of the sudoriparous glands. Nodular hidradenoma. Apropos of a case]. PMID- 4305283 TI - Hepatic lobectomy in childhood: effectws of x-ray and chemotherapy. PMID- 4305285 TI - [Case report of juvenile hepatoblastoma fetal type with successful hepatic lobectomy]. PMID- 4305286 TI - [Studies on Trichomonas vaginalis in the urological field. 4]. PMID- 4305287 TI - [The possibilities to study the function of the human cells in clinical cell research]. PMID- 4305289 TI - [Findings on the use of BHK21 cultures in research on modified or attenuated foot and-mouth disease viruses]. PMID- 4305288 TI - Histochemistry of 3 beta-hydroxysteroid dehydrogenase in human adrenal cortex in various pathological conditions. PMID- 4305291 TI - [Characteristics of vasomotor disorders in tumors of the pituitary region]. PMID- 4305290 TI - [Intravenous hormono-chemotherapy of pulmonary tuberculosis in case of drug resistant mycobacteria]. PMID- 4305292 TI - [Occurrence of giant cells in the lung]. PMID- 4305293 TI - Properties of phosphorylase kinase and its control in skeletal muscle. PMID- 4305294 TI - The role of cyclic AMP in the control of liver metabolism. PMID- 4305295 TI - Hormonal and non-hormonal control of glycogen synthesis-control of transferase phosphatase and transferase I kinase. PMID- 4305296 TI - The effects of ethanol on the metabolic activities of the liver. PMID- 4305297 TI - Nucleic acids of tumor viruses. PMID- 4305298 TI - Spectrofluorometry of dihydroxyphenylacetic acid in urine. PMID- 4305299 TI - The occurrence of bone and cartilage in mammary tumors. PMID- 4305300 TI - The chemical senses. PMID- 4305301 TI - Adrenal response to ACTH in patients with Prader-Willi syndrome, simple obesity, and constitutional dwarfism. PMID- 4305302 TI - Laboratory diagnosis of Japanese encephalitis. Comparison of the fluorescent antibody technique with virus isolation and serologic tests. PMID- 4305303 TI - Different responses of white and brown adipose tissue to drugs affecting lipolysis. PMID- 4305304 TI - Inhibition of L-alpha-glycerophosphate dehydrogenase by alkylammonium chlorides. PMID- 4305305 TI - Increased monoamine oxidase activity in isoproterenol-stimulated submaxillary glands. PMID- 4305306 TI - Mechanism of inhibition of histidine decarboxylase (Clostridium welchii) by 4 bromo-3-hydroxybenzyloxamine and amino-oxyacetic acid. PMID- 4305307 TI - Chemodectoma. PMID- 4305308 TI - Serum inhibitors of myxoviruses. PMID- 4305309 TI - The synthesis of hyaluronic acid in vitreous. II. The presence of soluble transferase and nucleotide sugar in the accellular vitreous gel. PMID- 4305310 TI - Diffuse external otitis--treatment of 175 ears with a new preparation (Synalar Otic). PMID- 4305311 TI - Polyamide layer chromatography of organophosphorus pesticides. PMID- 4305312 TI - Studies of metyrapone responses in patients with pituitary disease. PMID- 4305313 TI - A modified ovarian cholesterol depletion assay for luteinizing hormone. PMID- 4305314 TI - A comparison of the in-vitro actions of thyroid-stimulating hormone and cyclic 3',5'-adenosine monophosphate on the mouse thyroid gland. PMID- 4305315 TI - [Mandibular cylindroma]. PMID- 4305316 TI - [Transient anuria in decompensated liver cirrhosis during angiotensin (Hypertensin) infusion]. PMID- 4305318 TI - [Free radicals induced by the action of ultraviolet radiation on certain constituants of deoxyribonucleic acid]. PMID- 4305317 TI - Psychology of the scientist. 28. Speculations on nonverbal creativity. PMID- 4305319 TI - The effect of cobalt on the ultrastructure of mitochondria. PMID- 4305320 TI - Radiological characteristics of brain tumors infiltrating corpus callosum. PMID- 4305321 TI - Sleep disturbances in the acute alcoholic psychoses. PMID- 4305322 TI - Effects of chemotherapeutic agents on two lines of human breast carcinomas in tissue culture. PMID- 4305323 TI - Comparative investigation (skin tests) with natural and synthetic corticotrophin in allergic patients. PMID- 4305324 TI - Gluconeogenesis in biotin deficiency: in vivo synthesis of pyruvate holocarboxylase in biotin deficient rat liver. PMID- 4305325 TI - The physicochemical basis of the functioning of biological membranes: the conformation of valinomycin and its K+ complex in solution. PMID- 4305327 TI - Aflatoxicosis and trout hepatoma. PMID- 4305328 TI - [Importance of cytology in urologic oncology]. PMID- 4305326 TI - Purification and properties of 2, 3-diphosphoglyceric acid phosphatase from human erythrocytes. PMID- 4305329 TI - [Neurologic complications following lower leg and ankle injuries with special reference to tarsal tunnel and anterior tibialis syndromes]. PMID- 4305330 TI - Steroid dehydrogenases and steroids in gonads of the seaperch Cymatogaster aggregata Gibbons. PMID- 4305331 TI - Blood glucose in male toads (Bufo bufo): annual variation and hormonal regulation. PMID- 4305332 TI - Some evidence for the presence of a corticotrophin releasing factor (CRF) in the duck (Anas platyrhynchos). PMID- 4305333 TI - [Cytologic data on the adenohypophysis of the roach, a teleost fish]. PMID- 4305334 TI - Prolonged ganglionic facilitation and the positive afterpotential. PMID- 4305335 TI - Possible reactivating and sensitizing action of neuromyally acting agents. PMID- 4305336 TI - Effects of adrenocorticotropic hormone on avoidance behaviour of intact and adrenalectomized rats. PMID- 4305337 TI - [Primary vascular tumors of the lung (from 4 cases)]. PMID- 4305338 TI - Influence of microorganisms on oxygen consumption, carbon dioxide production and colonic temperature of rats. PMID- 4305339 TI - Modification of epinephrine-induced inhibition of transmission by tropolone and desipramine (desmethylimipramine) in the perfused superior cervical ganglion. PMID- 4305341 TI - Changes in ultrastructure and electroretinogram of bulfrog retina during development. PMID- 4305340 TI - Microbial contamination of antibiotic ophthalmic ointments. PMID- 4305342 TI - [Adrenal cortex and mineral metabolism. 1]. PMID- 4305343 TI - [On differential diagnosis of sellar and parasellar tumors]. PMID- 4305344 TI - Calcification in mucinous cell carcinoma of the stomach. PMID- 4305345 TI - [Toxic encephaloenteritis-epidemic caused by adenoviruses of type 3]. PMID- 4305346 TI - Functional reactivation and cytological restoration of pituitary grafts by continuous local intravascular infusion of median eminence extracts. PMID- 4305347 TI - A comparative study of the antitumor and antiviral activity of 1-beta-D arabinofuranosyl-5-fluorocytosine (FCA) and 1-beta-D-arabinofuranosylcytosine (CA). PMID- 4305348 TI - Mouse bone collagenase: isolation, partial purification, and mechanism of action. PMID- 4305349 TI - Effects of growth hormone administration on hepatic excretion of bromsulfalein (BSP). PMID- 4305351 TI - Temporal protection of chick embryo against endotoxin by isoproterenol, polymyxin B sulfate, and hydrocortisone. PMID- 4305350 TI - Effects of pargyline and amphetamine upon acute stress responses in rats. PMID- 4305352 TI - Interferon action in heterokaryons. PMID- 4305354 TI - Mixed tumors of salivary glands: a report from the Tumor Registry of the University of Michigan Medical Center. PMID- 4305353 TI - [Determination of renin activity and aldosteronuria in 24 hypertensives]. PMID- 4305355 TI - The Reynold L. Haas Memorial Lecture: gynecologic curiosities and concepts. PMID- 4305356 TI - [Afferent paresis and afferent ataxia in the clinical picture of focal lesions of the brain]. PMID- 4305357 TI - [The significance of statokinetic disorders in the neurologic diagnosis of tumors of the temporal lobe of the brain]. PMID- 4305358 TI - [Renin and angiotensin]. PMID- 4305359 TI - [Beta-langerhansian, insulin secreting tumor in a woman with diabetes mellitus. A case and review of the literature]. PMID- 4305360 TI - Hormonal regulation of myocardial adenosine 3',5'-monophosphate. PMID- 4305361 TI - The role of the alpha-glycerophosphate cycle in the control of carbohydrate oxidation in heart and in the mechanism of action of thyroid hormone. PMID- 4305362 TI - UDPglucose: alpha-I,4-glucan alpha-4-glucosyltransferase in heart regulation of the activity of the transferase in vivo and in vitro in rat. A dissociation in the action of insulin on transport and on transferase conversion. PMID- 4305363 TI - The influence of insulin and epinephrine on adenosine 3',5'-phosphate and glycogen transferase in muscle. PMID- 4305364 TI - Subcellular distribution of 3-hydroxy-3-methylglutaryl-CoA synthase, acetoacetyl CoA thiolase and NAD kinase in Saccharomyces cerevisiae. PMID- 4305365 TI - Fructose-1,6-diphosphatase and phosphopyruvate carboxykinase in bovine lactating mammary gland. PMID- 4305366 TI - Formation of a cobamide containing divalent cobalt by the ribonucleotide reductase of Lactobacillus leichmanii. PMID- 4305367 TI - Nucleotide diphosphate sugar pyrophosphatase activity in the skin of alloxan diabetic rats. PMID- 4305368 TI - [Inhibitors of adrenocrotical secretion]. PMID- 4305370 TI - Gel filtration behavior of calcium and magnesium salts in normal and stone forming urines. PMID- 4305369 TI - Catecholamine synthesis in rabbits with neurogenic hypertension. PMID- 4305371 TI - A general colorimetric procedure for the estimation of enzymes which are linked to the NADH-NAD+ system. PMID- 4305372 TI - Variant alkaline phosphatase in human hepatocellular cancers. PMID- 4305373 TI - [3 cases of septal tumors developed in the lateral ventricle with behavioral problems. "Schizophrenia" and cerebral tumors]. PMID- 4305374 TI - [Mental and pseudocerebellar semiology of thalamic tumors]. PMID- 4305375 TI - Parotid fluid cortisol and cortisone. AB - Parotid fluid corticosteroids, substantially comprised of cortisol and cortisone, were previously demonstrated to rise to far greater levels 4 hr after administration of ACTH than they did in the third trimester of pregnancy, although the plasma total corticosteroid concentrations were similar in these two states. It was therefore suggested that only nonproteinbound corticosteroid gains access to parotid fluid. In the present study parotid fluid cortisol and cortisone and plasma dialyzable cortisol concentrations have been measured in normal men before and 2 hr after 40 U ACTH, and, in another group, before and after 10 days of diethystilbestrol (5 mg daily). Total plasma cortisol rose from a mean of 6.3 to 17.9 mug/100 ml after ACTH and from 14.6 to 39.4 mg/100 ml after the estrogen. However parotid fluid cortisol plus cortisone rose from 0.8 to 2.6 mug/100 ml after ACTH and to only 2.2 after estrogen. This rise resembled that of the plasma dialyzable cortisol (control 0.4, ACTH 1.8, estrogen 1.2 mug/100 ml) rather than the increase in total plasma cortisol which was over twice as high after estrogen as after ACTH. Thus parotid fluid corticosteroids seem to be a good measure of nonprotein-bound corticosteroid, the cortisol available to the cell. The total amount of cortisol plus cortisone excreted is approximately constant, independent of parotid fluid flow rate. Cortisone exceeds cortisol in parotid fluid in the basal state, but after ACTH the situation is reversed. PMID- 4305376 TI - Plasma progesterone and 17-hydroxyprogesterone in normal men and children with congenital adrenal hyperplasia. AB - Plasma 17-hydroxyprogesterone (17-OHP) concentrations in normal men averaged 0.094 mug/100 ml. Studies using suppressive doses of androgens and glucocorticoids showed that 90% of the 17-OHP originated from the Leydig cell. The 17-OHP production rate was 1.8 mg/24 hr. Plasma 17-OHP has a marked circadian variation, the 8 p.m. values being only 40% of the 8 a.m. values. Plasma luteinizing hormone measured in the same samples did not vary. The adrenal cortex has the capacity to synthesize and secrete 17-OHP and progesterone since adrenocorticotrophic hormone (ACTH) caused a fourfold increase in these plasma steroids. In children with congenital adrenal hyperplasia, plasma 17-OHP levels were 50-200 times those of normal men and plasma progesterone was increased 6- to 10-fold over normal men. PMID- 4305378 TI - [Ovaribran in postmenopausal syndromes]. PMID- 4305377 TI - [Some aspects of steroid diabetes]. PMID- 4305379 TI - [Contribution to the study of myocardial damage in viral pneumopathies in infants]. PMID- 4305380 TI - [Mediastinoscopy. Results and complications]. PMID- 4305382 TI - [Progress in clinical diagnosis of peripheral nerve diseases. Record of the past 10 years]. PMID- 4305381 TI - [Report of 7 years of endolymphatic radiotherapy in the treatment of malignant lymphomas]. PMID- 4305383 TI - [Physiological myoclonus of the paradoxical phase of sleep]. PMID- 4305384 TI - [Digestive tract hemorrhages following ingestion of anti-inflammatory drugs]. PMID- 4305385 TI - [The heart in hyperthyroidism (83 cases). I. Clinical study]. PMID- 4305386 TI - [The heart in hyperthyroidism (83 cases). II. Treatment of cardiothyrotoxicosis]. PMID- 4305387 TI - [On 3 cases of hereditary cancer (cancerous degeneration of xeroderma pigmentosum)]. PMID- 4305388 TI - [Certain indices of cardiovascular activity in adenovirus diseases]. PMID- 4305389 TI - [The functional status of the adrenal cortex and corticosteroid therapy in infectious hepatitis and liver cirrhosis]. PMID- 4305391 TI - Mixed hemadsorption technique for study of avian leukosis-sarcoma viruses: standardization of the technique. PMID- 4305390 TI - A gel diffusion precipitin test for bovine papilloma virus. PMID- 4305392 TI - Mixed hemadsorption technique for study of avian leukosis-sarcoma viruses: studies with avian leukosis viruses. PMID- 4305393 TI - Search for natural nidality of influenza and parainfluenza viruses in Illinois. PMID- 4305394 TI - Immunodepression by viruses. PMID- 4305395 TI - Rapid identification of viruses by indirect immunofluorescence: standardization and use of antiserum pool to nine respiratory viruses. AB - The indirect fluorescent antibody test employing treated and standardized antisera and conjugated antiglobulin has been used successfully, in conjunction with a technique for growing and staining virus cell systems in situ on microscope slides, in the identification of nine respiratory viruses. By using pooled antisera in a single test, the presence or absence of these viruses was determined in 18 to 45 hr after inoculation of slide microtissue culture. PMID- 4305397 TI - Delay of poliovirus plaque formation with use of fresh bovine serum in the growth medium of host cells. AB - The plaque formation of poliovirus in HeLa cell monolayers was decreased upto 95% when the host cells were subcultured several times in a growth medium containing fresh bovine serum prior to their inoculation with virus. Extended incubation of infected cell monolayers indicated that the inhibition was in the form of a delay in plaque formation rather than a permanent inhibition of it. The inhibitory factor, which was found in most bovine sera, was very unstable and disappeared after storage of the serum at -20 C for a few weeks or at 36 C within a few days. In HeLa-cell monolayers, the fresh serum brought about a decrease in the plaque formation of all three poliovirus types as well as that of poliovirus ribonucleic acid. The plaque formation of poliovirus in monkey heart and HEp-2-cell monolayers was decreased irregularly by the use of fresh serum in the growth medium of these cells. Speculations were made as to the possible mode of action of the bovine serum inhibitor. PMID- 4305396 TI - Immunogenicity of namogram to milligram quantities of inactivated foot-and-mouth disease virus. I. Relative virus-neutralizing potency of guinea pig sera. AB - Quantitative antigen dose-neutralizing antibody response curves were established in guinea pigs for purified foot-and-mouth disease virus (FMDV), type A, strain 119, inactivated for 48 hr with N-acetylethyleneimine (AEI). Inactivation of FMDV by 0.05% AEI at 25 C occurred without virus degradation and followed first-order kinetics over a 10(8)-fold decrease in plaque-forming units (PFU) extrapolating to 10(-5) PFU/ml at 48 hr. The AEI-treated virus was administered in doses ranging from 10 ng to 2.62 mg, alone or emulsified in oil adjuvant. Sigmoidal dose-response curves were obtained with 160 ng as the minimum effective dose. The maximum effective dose was 163 mug and 2.62 mg or more at 6 and 28 through 84 days postinoculation, respectively. Oil adjuvant had little effect at 6 days postinoculation, but its use markedly increased the amount of neutralizing antibody obtained at the later testing periods. PMID- 4305398 TI - Modified Sabouraud medium containing neomycin and polymyxin. AB - A commercially available antibiotic mixture effectively decreased overgrowth of Sabouraud medium by gram-negative flora frequently found in the sputum of hospitalized patients. PMID- 4305399 TI - Foot-and-mouth disease virus: stability of neutralizing antibody after freeze drying and air-drying. AB - It is possible to stabilize foot-and-mouth disease antiserum by either freeze drying in bottles or air-drying on paper for periods of 7 months. PMID- 4305400 TI - Effects of actinomycin D on the oligonucleotide composition of nucleolar 45-S RNA of Novikoff hepatoma ascites cells. PMID- 4305401 TI - Herpes zoster and multiple sclerosis. AB - No significant difference was found between 50 consecutive patients with multiple sclerosis and matched controls in respect of previous infection with rubella or measles and chicken-pox, or of previous vaccination and immunizing injections. Significantly more patients had a past history of herpes zoster compared with the controls. PMID- 4305402 TI - Observations on an effect of ACTH, dexamethasone, and dimethyl sulfoxide on the "out of strain" transplantation and lethality of strain 2 guinea pig leukemia L2C NB to strain 13 and Hartley animals. PMID- 4305403 TI - Influence of dichlorophenylamino-imidazoline on the pressor response in the rat. PMID- 4305404 TI - [Review of corneal viral infection in its histopathological aspects]. PMID- 4305406 TI - Separation of cyclic-3',5'-adenosine monophosphate from other adenine nucleotides. PMID- 4305405 TI - Studies on the biosynthesis of the lipid and protein components of a membraneous cytochrome oxidase preparation of rat liver mitochondria in vivo. PMID- 4305407 TI - Hormonal and nutritional requirements for limb regeneration and survival of adult newts. PMID- 4305408 TI - The role of a renal thirst factor in drinking induced by extracellular stimuli. AB - 1. Rats in normal fluid balance drank water 1-2 hr after complete ligation of the inferior vena cava either above or below the renal veins. At the same time there was a fall in urine flow and excretion of electrolyte, especially after caval ligation above the renal veins, so that the animals ended the initial 6 hr period in positive fluid balance.2. Caval ligation was relatively ineffective as a stimulus to drinking after bilateral nephrectomy, but was effective in rats made anuric by ureteric ligation.3. Rats subjected to caval ligation and offered a choice between water and 1.8% saline (w/v) drank water, despite the increasing hypotonicity of the body fluids thereby resulting.4. During the secondary polydipsia, which generally occurred on about the third day after caval ligation as renal function was recovering, there was an increased preference for 1.8% saline.5. Constriction of the aorta above the renal arteries, or constriction of both renal arteries, also caused drinking, oliguria and the development of positive fluid balance.6. Constriction of the aorta below the renal arteries, or after nephrectomy, was ineffective as a stimulus to drinking.7. Saline extracts of renal cortex caused rats in normal water balance to drink. Activity was destroyed by boiling the extract for 10 min. Renal medullary and hepatic extracts were without effect on drinking.8. It proved impossible to separate dipsogenic and pressor activities of renal extracts during the different stages of fractionation which lead to the production of renin; disappearance of one activity was invariably accompanied by disappearance of the other.9. Dipsogenic and pressor actions were greater in nephrectomized rats than in normal rats.10. Both extractable dipsogenic factor and extractable pressor activity were reduced by treating the rat with DOCA and saline for several weeks beforehand.11. The renal dipsogen therefore has similar properties to renin. It may prove to be identical with renin, particularly in view of the fact that angiotensin also stimulates drinking.12. Adrenalectomy did not affect drinking induced by renin or by caval ligation.13. It is concluded that the renin angiotensin system may play a role in the genesis of the thirst which follows certain extracellular stimuli. PMID- 4305409 TI - The 1969 look in drug abuse control. PMID- 4305410 TI - Geriatrics. PMID- 4305411 TI - Mental health, psychotherapy, and the new psychotherapist. PMID- 4305412 TI - Courage to change. PMID- 4305413 TI - Perception of nursing role in a developing mental health center. PMID- 4305414 TI - Attitudes and behavior in response to nursing staff in mufti. PMID- 4305416 TI - Woodbridge State School. PMID- 4305415 TI - Modifying behavior: the case of Alice. PMID- 4305417 TI - Training psychiatric nurses in developing countries. PMID- 4305418 TI - Bacteremia and thrombus accumulation on prosthetic heart valves in the dog. PMID- 4305419 TI - Morphological and biochemical studies of virus (SV40) transformed prostatic tissue. PMID- 4305420 TI - [Antigenicity of tetracosactide (beta 1-24 ACTH). 1. Antigenicity of tetracosactide in rabbits]. PMID- 4305421 TI - [Antigenicity of tetracosactide (beta 1-24 ACTH). 2. Antigenicity of tetracosactide in guinea pigs]. PMID- 4305422 TI - [Large varicose ulcers infected by pyocyanic bacillus. Staphylococcal septicemia. Death due to renal insufficiency and uremic coma]. PMID- 4305423 TI - The critical incident form as a tool. PMID- 4305424 TI - Acute cardic care; the role of the registered nurse. A joint statement by the Minnesota State Medical Association, the Minnesota Heart Association and the Minnesota Nurses Association. PMID- 4305425 TI - Viral flora of chick and duck tissue sources. PMID- 4305426 TI - Characteristics of cell culture systems. Viral flora of canine tissues. PMID- 4305428 TI - Viral flora of primate tissues--discussion. PMID- 4305427 TI - Viral flora of tissue sources--simian and human. PMID- 4305429 TI - Variable susceptibility of human cell strains to SV40 transformation. PMID- 4305430 TI - Documentation and classification of oncogenic viruses. PMID- 4305431 TI - Viral oncogenesis and results of inoculation of normal and transformed cells into nonhuman primates. PMID- 4305433 TI - Detection of latent viruses in kidney tissues. PMID- 4305432 TI - Latent viral infections in donor tissues and in recipients of vaccines. PMID- 4305434 TI - Cooperative and antagonistic interactions among RNA tumor viruses. PMID- 4305435 TI - Viral oncogenicity and viral vaccines--general comments. PMID- 4305436 TI - Monitoring vaccines for human oncogenicity. PMID- 4305437 TI - Monitoring vaccines for human oncogenicity--discussion. PMID- 4305439 TI - Veterinary vaccines. PMID- 4305438 TI - Identification of established cell lines with reference to karyology. PMID- 4305441 TI - Experience with vaccines--general comments. PMID- 4305440 TI - Experience with an established cell line for veterinary vaccine production. PMID- 4305442 TI - Large-scale cultivation of animal cells in roller bottles for production of decigram amounts of pure foot-and-mouth disease virus. PMID- 4305443 TI - Rheumatoid arthritis. 2. Systemic manifestations. PMID- 4305444 TI - Sleep, dreams and computers. PMID- 4305445 TI - Immunological aspects of carcinogenesis. PMID- 4305447 TI - Quantum-mechanical investigations of the electronic structure of nucleic acids and their constituents. PMID- 4305446 TI - The interaction of chemical carcinogens and cells in vitro. PMID- 4305449 TI - Observations on the clinical features of carcinoma of the pancreas. PMID- 4305448 TI - Effect of flavonoids and related substances. II. Antiviral effect of quercetin, dihydroquercetin and dihydrofisetin. PMID- 4305450 TI - [On a case of recurrent peripheral neuropathy of the lower limbs with mild muscle hypertrophy. A neurophysiological study]. PMID- 4305451 TI - [Gammagraphic diagnosis of intracranial expansive processes with 99Tc pertechnate]. PMID- 4305452 TI - [Epidemic of pharyngo-conjunctival fever of adenovirus etiology in a home for infants]. PMID- 4305453 TI - [Sensitivity of referent human diploid cell strain WI-38 to different viruses. I. Enteroviruses]. PMID- 4305455 TI - Lipiodol absorption and urinary lodide excretion as a screening test for steatorrhea. PMID- 4305454 TI - [Contribution to the problems of long-term epidemiologic studies of acute viral respiratory diseases (ARD). I. Significance of longitudinal studies of acute respiratory diseases for the detection of influenza viruses in the pre-epidemic stage]. PMID- 4305456 TI - [Lipolytic activity of ACTH. IV. Research in the effect of extracted and synthetic corticotropin in nephrotic patients in the interval period of cyclic steroid therapy]. PMID- 4305457 TI - [Prolonged pregnancy]. PMID- 4305458 TI - [Effect of acidifying agents on the behavior of certain enzymes in ovarian cortex]. PMID- 4305459 TI - [Etiopathogenesis and therapy of Gross' mouse virus leukemia]. PMID- 4305460 TI - The preparation and properties of deflavo xanthine oxidase. PMID- 4305461 TI - Sugar phosphate phosphohydrolase. II. Effects of glucose on its activity and biosynthesis in Neisseria meningitidis. PMID- 4305462 TI - Conversion of light to chemical free energy. I. Porphyrin-sensitized photoreduction of ferredoxin by glutathione. PMID- 4305463 TI - Mechanism of action of amino acid transfer ribonucleic acid ligases. PMID- 4305464 TI - Destruction of insulin effector system of adipose tissue cells by proteolytic enzymes. PMID- 4305465 TI - The separation of the phosphodiesterase and deoxyribonuclease II activities of bovine spleen. PMID- 4305466 TI - Regulatory mechanisms involving nicotinamide adenine nucleotides as allosteric effectors. I. Control characteristics of malate dehydrogenase. PMID- 4305467 TI - Optical rotatory dispersion of mitochondrial reduced diphosphopyridine nucleotide dehydrogenase from cardiac tissue. PMID- 4305468 TI - The nature of tetraphenylboron-dissociated brain and brain tumor cells. PMID- 4305469 TI - [Precocious puberty]. PMID- 4305470 TI - [Remote results of 163 operations of adenoma of the pituitary gland]. PMID- 4305472 TI - [Histoenzymatic studies in hematology]. PMID- 4305471 TI - [A case of hypoglycemic beta-langerhansian adenoma and secreting parathyroidian adenoma: polyadenomatosis]. PMID- 4305473 TI - [Clinical studies on a pleiomorph adenoma of the minor salivary glands of the palate]. PMID- 4305474 TI - [Characteristics of the immunological reaction in children with parainfluenza]. PMID- 4305475 TI - [The role of copper in phosphorus-calcium metabolism (review of the literature)]. PMID- 4305476 TI - [Roentgenologic studies of the salivary glands with special reference to the aimed fractionated sialography]. PMID- 4305477 TI - Glycogenolytic effect of dibutyryl cyclic adenosine 3',5'-monophosphate in perfused rat liver. PMID- 4305478 TI - Stress-induced alterations in arylesterase activity in the rat. PMID- 4305479 TI - The effect of ethanol and cyanide on NAD-NADH2 ratios in rat liver. PMID- 4305480 TI - The biochemical mechanism of action of the antinematodal drug tetramisole. PMID- 4305481 TI - Effects of chlorpromazine on behaviour of some enzymes of rat liver in different experimental conditions. PMID- 4305482 TI - Studies on poisoning by Macrozamia communis. I. Biochemical disturbances in the liver. PMID- 4305483 TI - Hedamycin and rubiflavin complexes with deoxyribonucleic acid and other polynucleotides. PMID- 4305484 TI - Studies on the mechanism of inhibition of glutamine synthetase by methionine sulfoximine. PMID- 4305485 TI - Interaction of the 5-methylphenazinium cation radical with deoxyribonucleic acid. PMID- 4305488 TI - Inhibition of phospholipase C by phosphonate analogs of glycerophosphatides. PMID- 4305486 TI - Studies on the kinetics of formation and dissociation of the actomyosin complex. PMID- 4305487 TI - Rat kidney glycerylphosphorylcholine diesterase. PMID- 4305489 TI - The structures of enzymically produced diphosphoinositide and triphosphoinositide. PMID- 4305490 TI - The turnover of myelin in the adult rat. PMID- 4305492 TI - The detection of lipids on thin-layer chromatograms with the periodate-Schiff reagents. PMID- 4305491 TI - Studies on the reaction of cytochrome c with corticosteroids. PMID- 4305493 TI - Factors in the diagnosis of breast disease. PMID- 4305494 TI - Adenoid cystic carcinoma of the breast. PMID- 4305495 TI - Simulation of phosphate excretion by the renal arterial infusion of 3'5'-AMP (cyclic AMP)-a possible mechanism of action of parathyroid hormone. PMID- 4305496 TI - Interactions of parathyroid hormone, thyroxine and calcitonin. PMID- 4305497 TI - Changes in DNA-bound amino acids in experimental tumor transplants. PMID- 4305498 TI - The sex-dependent difference in the development of liver tumors in mice administered dimethylnitrosamine. PMID- 4305499 TI - Acid hydrolase activity during the induction and transplantation of hepatomas in the rat. PMID- 4305500 TI - Inhibition of the growth of mouse polyoma tumors by lymph node fragments from specifically immunized rats. PMID- 4305501 TI - Stimulation of aldosterone secretion by sodium depletion in nephrectomized rats. PMID- 4305503 TI - Sensitivity of the adrenal corticosterone response to ACTH as a function of time after hypophysectomy. PMID- 4305502 TI - In vivo effect of sex hormones on the in vitro synthesis of prolactin and growth hormone in normal and pituitary tumor-bearing rats. PMID- 4305504 TI - [Electron microscopic observations with experimental poloimyelitis]. PMID- 4305506 TI - The effect of heat-treatment and UV-irradiation on x-ray induced electron spin resonance centers in valine. PMID- 4305505 TI - [Decreased reactivation of reduced RNase by Zajdela-hepatoma-ascites cells]. PMID- 4305507 TI - Effects of dopamine and ACTH on steroid sensitive single neurones in the basal hypothalamus. PMID- 4305508 TI - [Physiologic investigations of the innervation of smooth muscles of bird feathers (Mm. pennarum)]. PMID- 4305509 TI - The effect of haloperidol on the sleep cycle of the cat. PMID- 4305510 TI - Liver regeneration after partial hepatectomy in rats exposed before the operation to the stress stimulus. PMID- 4305511 TI - Adrenal and clinical responses to corticotrophin and prednisone in inflammatory disease of the colon. PMID- 4305512 TI - [Cramps in childhood. 2. Epilepsy--types of attacks--diagnosis--therapy]. PMID- 4305513 TI - [Paradoxic sleep and neuropsychiatric illnesses]. PMID- 4305515 TI - Dehydrogenase and nucleoproteid histochemistry of the juxtaglomerular complex. PMID- 4305514 TI - [Supplementary studies on the problem of tumor specificity of N-acetyl-D galactosamine in the rat]. PMID- 4305516 TI - Response of the adrenal gland to the activation of the subcommissural organ in the pigeon. PMID- 4305517 TI - [Recent observations on vitamin B 12 deficiency and neurological degeneration in monkeys in captivity]. PMID- 4305518 TI - [Study of pertussis using nerve tissue culture. 3. Effect of pertussis toxoid and the action of immune serum on cultured nerve elements]. PMID- 4305519 TI - Penetration of circulating fluorescent proteins into walls of arterioles and venules in rats with intermittent acute angiotensin-hypertension. PMID- 4305520 TI - Cancer metastasis to the cirrhotic liver. A study of experimental and autopsy material. PMID- 4305521 TI - Improved methods for gonococcal sampling and examination on a large scale. PMID- 4305522 TI - Respiratory syncytial virus complement fixing antibodies. Evidence of the 7S nature of antibodies determined with dextran added to the test system. PMID- 4305523 TI - Distribution of protein-bound N-acetylneuraminic acid in subcellular particulate fractions prepared from rat whole brain. PMID- 4305524 TI - Ketogenesis in vitro. PMID- 4305525 TI - Sources of nitrogen as rate-limiting factors for purine biosynthesis de novo in Ehrlich ascites tumor cells. PMID- 4305526 TI - [Complications in oil lymphography--a report on 1,000 lymphographic examinations]. PMID- 4305527 TI - Value of tomography in the diagnosis of the glomus jugulare tumors. PMID- 4305528 TI - Experimental studies on the effect of antibiotics and anticancer compounds on the phagocytic activity of the reticuloendothelial system (R.E.S.). PMID- 4305529 TI - The susceptibility of Clostridium perfringens type A to ampicillin and penicillin G in vitro. PMID- 4305530 TI - Inhibition by pyrophosphate and polyphosphate of aortic calcification induced by vitamin D3 in rats. PMID- 4305531 TI - Incorporation of phospholipid precursors into isolated rat liver mitochondria. PMID- 4305533 TI - Breakdown of double-stranded RNA by bull semen ribonuclease. PMID- 4305532 TI - [Studies on the structure of ferredoxin]. PMID- 4305535 TI - A convenient spectrophotometric assay for phosphodiesterases, using dinucleoside monophosphates as substrates. PMID- 4305534 TI - Studies of the energy-transfer system of submitochondrial particles. Kinetic studies of the effect of oligomycin on the respiratory chain of EDTA particles. PMID- 4305536 TI - Stimulation of fructose 1,6-diphosphatase by sulfhydryl reagents and interaction between the different enzymic sites in the molecule. PMID- 4305537 TI - Cytochrome oxidase apoprotein in "petite" mutant yeast mitochondria. Reconstitution of cytochrome oxidase by combining apoprotein with cytohemin. PMID- 4305538 TI - The nucleotide sequence of N-formyl-methionyl-transfer RNA. Products of complete digestion with ribonuclease T-1 and pancreatic ribonuclease and derivation of their sequences. PMID- 4305539 TI - [Certain aspects of the activity of receptor formations]. PMID- 4305540 TI - [On Wedenski's pessimal inhibition in muscle fibers on the "tonic" skeletal muscle system of the frog]. PMID- 4305541 TI - [Influence of stimulation of posterior spinal roots on the size of motoneuron synapses and on anterior root potentials]. PMID- 4305542 TI - [Influence of physical training on neurohumoral changes and protein morphogenesis]. PMID- 4305543 TI - Study of a blood-free medium for transport and growth of Bordetella pertussis. PMID- 4305544 TI - [Peripheral nerve disorders in acute SLE]. PMID- 4305545 TI - [Combined chemotherapeutic and surgical treatment of patients with neglected forms of cancer of the stomach]. PMID- 4305546 TI - [A case of mixed tumor of the parotid gland]. PMID- 4305547 TI - Post synaptic stimulation of the electrogenic sodium pump. PMID- 4305548 TI - [2 cases of nonchromaffin paraganglioma (chemodectoma) of the mediastinum]. PMID- 4305550 TI - [Viral neuropathy]. PMID- 4305549 TI - [Viral hepatitis. Introductory report]. PMID- 4305551 TI - [Experimental contribution to the study of dysplastic fibrosocystic processes of the tongue]. PMID- 4305552 TI - Bronchiolar (alveolar cell) carcinoma of lung. PMID- 4305553 TI - [Determination and evaluation of the activity of Angiotensin II]. PMID- 4305554 TI - [Diagnostic significance of the angiotensin infusion test]. PMID- 4305555 TI - [Acute renal failure following abortion]. PMID- 4305556 TI - [Observations on the fine struture of Entamoeba histolytica in vitro and in experimental amebiasis in the rat. Ultrastructural research]. PMID- 4305558 TI - [On the clinical features of maxillary cylindroma (adenoid cystic carcinoma)]. PMID- 4305559 TI - [Several problems of radiation therapy of Wilms tumor in children]. PMID- 4305557 TI - Recent advances in antibiotics. PMID- 4305561 TI - Runting syndromes, autoimmunity, and neoplasia. PMID- 4305560 TI - The carcinogenic action and metabolism of urethan and N-hydroxyurethan. PMID- 4305562 TI - Cyclic AMP: role of the medicinal chemist. PMID- 4305563 TI - Hormonal effect on nucleolar RNA polymerase in normal liver and hepatoma cells. PMID- 4305564 TI - Glycolytic regulation in rat liver and hepatomas. PMID- 4305565 TI - Analysis of nucleic acid derivatives at the subnanomole level. 3. A tritium labeling procedure for quantitative analysis of ribose derivatives. PMID- 4305566 TI - Cyclic 3',5'-nucleotide phosphodiesterase. A continous titrimetric assay. PMID- 4305567 TI - Enzymic assay method for inorganic pyrophosphate. PMID- 4305568 TI - Synthesis of nicontinamide-adenine dinucleotide by NAD pyrophosphorylase on a column of hydroxylapatite. PMID- 4305569 TI - Enzymic analysis of cyclic 3', 5'-AMP in mammalian tissues and urine. PMID- 4305571 TI - Biochemical changes in rat liver in response to treatment with drugs and other agents. 3. Effects of centrally acting drugs. PMID- 4305572 TI - [Special technics for the examination of paranasal sinuses]. PMID- 4305573 TI - Effect of theophylline on acid secretion of stimulated human gastric mucosa. PMID- 4305574 TI - On the heterogeneity of skeltal muscle fibers: the intermediate fibers. PMID- 4305575 TI - [On the chemodifferentiation of rat stem ganglia]. PMID- 4305576 TI - [Polarographic determination of sergosin]. PMID- 4305577 TI - [Physician's responsibility in the use of anabolic steroids in relation to the voice]. PMID- 4305578 TI - Studies on the adaptation of Afircan horse sickness virus to adult hamsters. PMID- 4305579 TI - Phospholipids of Nocardia coeliaca. AB - The lipids of Nocardia coeliaca were separated into at least 10 components by the use of thin-layer chromatography. Phosphatidylcholine was the most abundant phospholipid in this organism, accounting for 25 to 40% of the total phospholipids. The major fatty acid components of the phosphatidylcholine were 14 methyl-pentadecanoic acid (41%), the other C(15) and C(17) iso- and anteiso-fatty acids (29%), and palmitic acid (13.5%). The next most abundant phospholipid was phosphatidylethanolamine (25 to 30%), followed by phosphatidylinositol (11 to 14%) and cardiolipin (7 to 15%). Phosphatidylethanolamine and phosphatidylinositol were very similar to the phosphatidylcholine in fatty acid composition, whereas cardiolipin was characterized by a higher content of palmitic acid (30%). In all of the phospholipids examined, only trace amounts of monounsaturated fatty acids were present. When washed cells of N. coeliaca were incubated with methionine-methyl-(14)C for 1 to 3 hr, the radioactivity was mainly incorporated into the choline moiety of the phosphatidylcholine. In contrast, acetate-1-(14)C or glycerol-1-(14)C was incorporated much more slowly into the phosphatidylcholine than into the other phospholipids and neutral lipids. No phosphatidylcholine was detected in 10 other species of Nocardia examined. PMID- 4305580 TI - Restoration by ubiquinone of Azotobacter vinelandii reduced nicotinamide adenine dinucleotide oxidase activity. AB - Extraction with pentane virtually abolished reduced nicotinamide adenine dinucleotide oxidase activity in small particles from Azotobacter vinelandii, but activity was largely restored by added ubiquinone. PMID- 4305581 TI - Radical formation in x-irradiated glycine HC1. PMID- 4305583 TI - [Malignant synovioma of the sacro-iliac joint]. PMID- 4305582 TI - The neuroanatomy of Hymenolepis diminuta and H. nana. PMID- 4305584 TI - [On the surgical treatment of primary cancer of the liver]. PMID- 4305585 TI - The influence of 5HT on the heart phosphorylase activity in the snail, Lymnaea stagnalis L. PMID- 4305586 TI - Chromatin phosphatides and phosphoprotein. PMID- 4305587 TI - The use of estrone-protein conjugates in the study of the in vivo fate of antigen. PMID- 4305588 TI - Effect of muscle acyl phosphatase on the amino acid incorporation in cell-free systems. PMID- 4305589 TI - [Contribution to the study of hypophosphatasia]. PMID- 4305590 TI - Renal hypertension in rabbits immunized with angiotensin. PMID- 4305591 TI - [Pseudogout syndrome]. PMID- 4305592 TI - Understanding physical change. PMID- 4305593 TI - [Significance of measuring the urinary excretion of folic acid for the diagnosis of lung and bronchial neoplasms]. PMID- 4305595 TI - Cancer of the gastrointestinal tract in young people. PMID- 4305594 TI - Diseases of sweat and sebaceous glands, hair and nails. PMID- 4305596 TI - Accumulation of 3H-noradrenaline in cardiac and smooth muscle of rats with experimental hypertension. PMID- 4305597 TI - Studies of control of tissue protein levels: differential responses of tumor and liver to fasting. PMID- 4305598 TI - Synaptic responsiveness in the lateral geniculate nucleus of the alert cat. PMID- 4305599 TI - The effect of retinal illumination and retinal blockade on synaptic transmission in the lateral geniculate nucleus of the cat. PMID- 4305600 TI - Cytomegalovirus infection during pregnancy. A prospective study and report of six cases. PMID- 4305602 TI - ESR studies of copper(II) complex ions. PMID- 4305601 TI - D-Fructose-1,6-diphosphatase of navy bean (Phaseolus vulgaris L.) leaves. PMID- 4305603 TI - The interaction of organic and inorganic phosphates with hemoglobin. PMID- 4305604 TI - Studies on ribonuclease produced by Rhizopus sp. I. Crystallization and some properties of the ribonuclease. PMID- 4305605 TI - Allergic encephalomyelitis: cleavage of the C-tryptophyl bond in the encephalitogenic basic protein from bovne myelin. PMID- 4305606 TI - Control of ATP-dependent CO2 fixation in extracts of Hydrogenomonas facilis: NADH regulation of phosphoribulokinase. PMID- 4305607 TI - Inhibitors of photophosphorylation and photoreduction by chromatophores from Rhodospirillum rubrum. PMID- 4305608 TI - Inhibition of energy transfer reactions in mitochondria by hydroxylamine. PMID- 4305609 TI - Incorporation of tritiated thymidine into the cytoplasm of PAS positive reticular cells in x-irradiated mouse thymus. PMID- 4305610 TI - Eye signs of hypophosphatasia. PMID- 4305611 TI - Multiple congenital abnormalities associated with cryptophthalmia. PMID- 4305612 TI - A new enzyme for the interconversion of pyruvate and phosphopyruvate and its role in the C4 dicarboxylic acid pathway of photosynthesis. AB - 1. An enzyme was isolated from leaves of tropical grasses that catalyses the reversible conversion of pyruvate, ATP and orthophosphate into phosphopyruvate, AMP and pyrophosphate. A requirement for Mg(2+) could not be replaced by Mn(2+) or Ca(2+). 2. By replacing orthophosphate with [(32)P]orthophosphate or with arsenate, evidence was provided that the orthophosphate consumed appears in pyrophosphate. 3. Without Mg(2+) or 2-mercaptoethanol the enzyme was rapidly and irreversibly inactivated. EDTA only partially replaced the requirement for the thiol compound. The enzyme was considerably more unstable at 0 degrees or when frozen than at 22 degrees . Even with the best conditions devised the enzyme lost about 25% of its activity every 3hr. 4. The activities of the enzyme in leaves of the tropical grasses sugar cane (Saccharum hybrid var. Pindar), maize (Zea mays) and sorghum (Sorghum vulgare) were comparable with their maximum photosynthesis rates. The enzyme was not detectable in leaf extracts from several other plants. 5. Its role in photosynthesis is discussed. PMID- 4305613 TI - Sources of alcohol dehydrogenase (NAD+-linked) in the cockroach, Leucophaea maderae. PMID- 4305615 TI - A technique of two phase carotid angiopolygraphy. PMID- 4305614 TI - Regulation of NAD-specific alcohol dehydrogenases in Neurospora crassa. PMID- 4305617 TI - Linitis plastica of the colon. PMID- 4305616 TI - The direct irradiation of cerebral gliomata. PMID- 4305618 TI - Effect of ACTH and metyrapone on estriol, 17-hydroxycorticosteroid, 17 ketosteroid, pregnanediol and pregnanetriol excretion late in pregnancy. PMID- 4305619 TI - Thyroid iodine content and turnover in euthyroid subjects: validity of estimation of thyroid iodine accumulation from short-term clearance studies. PMID- 4305620 TI - Evidence that chlorpropamide and vasopressin share a common site of action. PMID- 4305621 TI - Temporal aspects of anticholinergic-and anticholinesterase-induced amnesia for an appetitive habit. PMID- 4305622 TI - Retrograde amnesia produced by hypothermia in rats. PMID- 4305623 TI - Idiopathic hypoglycemia: a study of twenty-six children. PMID- 4305624 TI - Virus-like particles in sera of patients with infectious and serum hepatitis. PMID- 4305625 TI - Adenovirus infection in intussusception in children in Taiwan. PMID- 4305626 TI - Prevalence of antibodies to EB virus and other herpesviruses. PMID- 4305627 TI - Hepatitis virus at last? PMID- 4305628 TI - Acute gout--definitely a medical emergency. PMID- 4305629 TI - Mistaken diagnosis of benign parotid tumor with facial paralysis. PMID- 4305630 TI - Paget's disease in the female breast. PMID- 4305631 TI - Infectious replicative intermediate of poliovirus: purification and characterization. PMID- 4305632 TI - Analysis of poliovirus-specific RNA in infected HeLa cells by polyacrylamide gel electrophoresis. PMID- 4305633 TI - Some characteristics of an isolated group antigen common to most strains of murine leukemia virus. PMID- 4305635 TI - Absence of repressor in SV40-transformed cells. PMID- 4305634 TI - The interaction of tritium-labelled mengo virus RNA and L cells: the effects of DMSO and DEAE-dextran. PMID- 4305636 TI - Correlation between the synthesis of DNA and histones in polyoma virus-infected mouse embryo cells. PMID- 4305637 TI - Utilization of substrate analogs by mengovirus induced RNA polymerase. PMID- 4305639 TI - The ionization constant of nicotinamide-adenine dinucleotide. PMID- 4305640 TI - New fluorometric method for the determination of cortisol in serum. PMID- 4305641 TI - [Value of technetium-99m in cerebral scintigraphy]. PMID- 4305638 TI - Postirradiation malignant neoplasms of the uterine fundus. PMID- 4305642 TI - [Aortographic exploration of various abdominal tumors in children]. PMID- 4305643 TI - [Nephroblastoma and aniridia]. PMID- 4305644 TI - Histochemical observations on the developing foot of normal, oligosyndactylous (Os-plus) and syndactylous (sm-sm) mouse embryos. PMID- 4305645 TI - [Activity of 4 dephosphorylating enzymes during morphogenesis of the primary palate in rats. (Alkaline phosphatase, acid phosphatase, ATP- and AMPases)]. PMID- 4305646 TI - Lack of cell proliferation in the foci of variola virus-infected FL cells. PMID- 4305647 TI - Immune hemadsorption by cells infected with poxviruses. PMID- 4305648 TI - L.C.A.O.-M.O. calculations on isomeric methyleneindenes. PMID- 4305649 TI - Sleep patterns during afternoon naps in the young and elderly. PMID- 4305650 TI - Hyperemia of the salivary gland in cytomegalic inculusion disease. PMID- 4305651 TI - An electron microscopic study of human salivary gland tumors. Pleomorphic adenoma and adenoid cystic carcinoma. PMID- 4305652 TI - [Problem of corticosteroid administration in intensive treatment of acute cerebrovascular accidents]. PMID- 4305653 TI - The antiviral activity of 9-beta-D-arabinofuranosyladenine (ARA-A). PMID- 4305654 TI - Effects of some anticholinergic drugs on antidromic activity in the rat phrenic nerve-diaphragm preparation. PMID- 4305655 TI - Response of the nictitating membrane to prostaglandin E1 and angiotensin. PMID- 4305656 TI - Catalase of tumor-bearing animals. I. Combined immunochemical and enzymic determination of catalase in liver cell fractions. PMID- 4305657 TI - Catalase of tumor-bearing animals. II. Chromatographic analysis of liver catalase. PMID- 4305658 TI - Antitumor effect of actinomycin-D on transplantable Wilms tumor in rats. PMID- 4305659 TI - Distribution of N-methyl [14C]-bis (3-mesyloxypropyl)-amine hydrochloride and its metabolites in normal and tumor-bearing rats. PMID- 4305661 TI - Establishment of a milk agent-free substrain C3HeB-Os and effect of foster nursing on occurrence of mammary tumors. PMID- 4305660 TI - Effectiveness of cytosine arabinoside therapy on leukemia (L-1210) of the central nervous system in mice arising during methotrexate treatment. PMID- 4305662 TI - Induction of liver tumor in mice injected at birth with liver tumor extract. PMID- 4305663 TI - [Metabolic changes in the course of hyperbaric radiotherapy]. PMID- 4305664 TI - Thymidine kinases from normal and tumor tissues. PMID- 4305665 TI - The lens capsule. Studies on the carbohydrate units. PMID- 4305666 TI - Metabolism of pyruvate and L-lactate by rat adipose tissue. PMID- 4305667 TI - The enzymes of the galactose operon in Escherichia coli. II. The subunits of uridine diphosphogalactose 4-epimerase. PMID- 4305668 TI - Stimulation of tryptophanase synthesis in Escherichia coli by cyclic 3',5' adenosine monophosphate. PMID- 4305670 TI - A modification of Kerley's method for the microscopic determination of age in human bone. PMID- 4305669 TI - Further studies on the sites of action of clopamide and furosemide. PMID- 4305671 TI - Measurement of acidity and equilibria in glacial acetic acid with the glass calomel electrode system. PMID- 4305672 TI - Effect of polysorbate 80 and of sodium lauryl sulfate on the photodegradation of flavin mononucleotide: a kinetic study with electron spin resonance. PMID- 4305673 TI - Synthesis of ribonucleic acid in cells infected with LSc poliovirus at elevated temperatures. AB - The synthesis of viral ribonucleic acid (RNA) was detected within 2 hr after infection with LSc poliovirus at 35 C. This RNA eluted as a single peak with 0.9 m NaCl on methylated albumin celite columns, was sensitive to ribonuclease, precipitated in the presence of 2 m LiCl, and had an S(20) value at 34 +/- 2 in linear sucrose gradients. When cells were infected at 39 to 40 C, there was also early synthesis of RNA. However, 2 hr after infection this synthesis was drastically inhibited. The absence of net RNA synthesis at 39 to 40 C during the late stages of infection was not caused by rapid degradation of newly formed RNA, since the RNA produced between 1 and 2 hr at 39 to 40 C was still present 3.5 hr after infection. There was a 3 log(10) inhibition in the production of infectious virus when p-fluorophenylalanine was present in the medium at a concentration of 25 mug/ml. This concentration of analogue had little effect upon the production of viral polymerase and viral RNA. Virus grown in the presence of analogue at a concentration of 10 mug/ml exhibited increased heat sensitivity compared to control virus. However, viral polymerase exhibited no change in sensitivity to heat or manganese when cells were exposed to 25 mug of p-fluorophenylalanine per ml during infection. p-Fluorophenylalanine had a relatively selective effect on viral capsid protein but did not reverse the inhibition of synthesis of viral RNA at 39 to 40 C. PMID- 4305674 TI - Recombination between guanidine-resistant and dextran sulfate-resistant mutants of type 1 poliovirus. AB - Mixed infection of monkey kidney cells with two mutants of the LSc2ab strain of poliovirus, one resistant to guanidine and the other resistant to both dextran sulfate and 2-(alpha-hydroxybenzyl)-benzimidazole (HBB), yielded progeny in which the number of gua(r)dex(r) particles exceeded by a factor of 7 to 10 the expected number of similar particles occurring through spontaneous mutation; recombination would explain the fairly high excess of doubly mutant particles that was obtained. Scoring of HBB resistance in 50 gua(r)dex(r) clones suggested that, during recombination, resistance to dextran sulfate is not associated with HBB resistance. PMID- 4305675 TI - Specific effect of guanidine in the programming of poliovirus inhibition of deoxyribonucleic acid synthesis. AB - Inhibition of HeLa cell deoxyribonucleic acid (DNA) synthesis, which occurred by the 4th to 5th hr after infection with poliovirus, could be blocked completely by guanidine only when it was present before the 2nd hr. At the 2nd hr, there was no significant ribonucleic acid (RNA)-replicase activity, and addition of guanidine inhibited all production of virus but allowed 57% of maximal DNA inhibition to develop. Maximum DNA inhibition developed in cells infected for 4 hr in the presence of guanidine when the guanidine was removed for a 10-min interval. RNA replicase activity was not enzymatically detectable and viral multiplication did not develop in these cells unless the interval without guanidine was extended to 60 min. The interpretation of the data was that the effect of guanidine on viral induced inhibition of DNA synthesis was distinct and not a consequence of the inhibition of RNA-replicase. PMID- 4305676 TI - The inhibitory effect of diphtheria toxin on amino acid incorporation by a bacterial cell-free system. PMID- 4305677 TI - [Can admission to hospital be advoided?]. PMID- 4305678 TI - Metabolism of glyceryl 1-14C-trilinoleate in rat testis. PMID- 4305679 TI - Another look at corticotrophin therapy: clinical and biochemical assessment. PMID- 4305680 TI - [Our experiences with Conevril in diseases of the peripheral nervous system]. PMID- 4305681 TI - [Virus infections of the oral mucosa and aphthous diseases with still unknown etiology]. PMID- 4305682 TI - [Medical virology and its importance in medical practice]. PMID- 4305683 TI - [Clinical aspects and therapy of shigellosis in childhood]. PMID- 4305684 TI - Cytomegalovirus infection and the postperfusion syndrome. Recognition of primary infections in four patients. PMID- 4305685 TI - Results of treatment and clinico-electroencephalographic evolution of infantile spasms. PMID- 4305686 TI - Blood renin levels in various types of arterial hypertension. Preliminary communication. PMID- 4305687 TI - The effect of ACTH upon patients having regional enteritis. PMID- 4305688 TI - Medical grand rounds from the University of Alabama Medical Center. PMID- 4305689 TI - [Clinical and therapeutic problems of tumorous forms of angioma in otorhinolaryngology]. PMID- 4305690 TI - [Neurophysiologic observations on the subject of depression]. PMID- 4305691 TI - [Viomycin derivatives. IV. Preparation and properties of some penicillinates]. PMID- 4305692 TI - One-electron-transfer reactions in biochemical systems. II. The reaction of free radicals formed in the enzymic oxidation. PMID- 4305693 TI - Electron transport and phospholipase activity in encysting cells of the ciliate Colpoda steinii. PMID- 4305694 TI - Proteolipids. V. The activity of lipid cytochrome C. PMID- 4305695 TI - Inactivation of lyophilized DPNH dehydrogenase from Escherichia coli by oxygen. PMID- 4305696 TI - Generation of reducing power in chemosynthesis. V. The mechanism of pyridine nucleotide reduction by nitrite in the chemoautotroph Nitrobacter agilis. PMID- 4305697 TI - Delayed light studies on photosynthetic energy conversion. II. Effect of electron acceptors and phosphorylation cofactors on the millisecond emission from chloroplasts. PMID- 4305698 TI - Induction of respiratory metabolism in illuminated Chlorella pyrenoidosa and isolated spinach chloroplasts by the addition of vitamin K5. PMID- 4305700 TI - Interaction between NADH and succinate during simultaneous oxidation by non phosphorylating submitochondrial particles from bovine heart. PMID- 4305699 TI - Energy-linked reactions in digitonin particles from beef-heart mitochondria. PMID- 4305701 TI - [Lipolytic activity of ACTH. I. Research on the effect of extracted and synthetic corticotropin on normal subjects]. PMID- 4305703 TI - [On the immunohistologic localization of ACTH in the rat pituitary]. PMID- 4305702 TI - Transitory primary aldosteronism-like condition. PMID- 4305704 TI - Catalase activity of serum and hepatic tissue in experimental murine hepatitis by MHV-3 virus and in acute experimental CCl-4 poisoning. PMID- 4305706 TI - [Aerosil and its use in pharmaceutical practice]. PMID- 4305705 TI - [Comparative study of metabolic changes in rat liver after administration of ethanol or other compounds. IV. The case of an intraperitoneal injection of glucose]. PMID- 4305707 TI - Cytomegalovirus infection in chronic liver disease. PMID- 4305708 TI - Small intestinal histochemical and histological changes in ulcerative colitis. PMID- 4305710 TI - [Results obtained from bronchologic investigation of primary bronchopulmonary cancers. Theoretical and practical deductions]. PMID- 4305709 TI - Aetiology of ulcerative colitis. PMID- 4305711 TI - Biosynthesis of squalene and cholesterol by cell-free extracts of adult rat brain. AB - Cell-free extracts of adult rat brain incubated with mevalonic acid-2-(14)C synthesize (14)C-labeled nonsaponifiable fractions consisting largely of squalene (14)C. If the cofactor concentrations of the incubation medium are adjusted, much of the squalene can be induced to undergo turnover, with a resultant increase in (14)C-labeled digitonin-precipitable sterols, which include a small amount of cholesterol. The synthesis of labeled sterols is markedly increased in the presence of Mg(++) and depressed by nicotinamide. ATP, NADH, GSH, and glucose-6 phosphate are required for optimal synthesis of digitonin-precipitable material but, unlike Mg(++), are not essential. The cofactor-adjusted extracts also synthesize a complex ester mixture containing, in addition to cholesterol-(14)C, several compounds less polar than cholesterol. The biosynthesis of cholesterol in the extracts is a slow process; at least 12 hr of incubation is required for maximal sterol biosynthesis. A complex mixture of hydrocarbons accompanies squalene in the incubated extracts. PMID- 4305712 TI - Mechanism of squalene biosynthesis: evidence against the involvement of free nerolidyl pyrophosphate. AB - Several mechanisms that utilize farnesyl pyrophosphate and nerolidyl pyrophosphate as condensing substrates have been postulated for the asymmetric condensation reaction in squalene biosynthesis. Although there is ample evidence that farnesyl pyrophosphate is a substrate for this reaction, there has been no information concerning the role of nerolidyl pyrophosphate. We have made the following observations that demonstrate that nerolidyl pyrophosphate cannot be a free intermediate in squalene biosynthesis. (a) There is no significant interconversion of farnesyl pyrophosphate and nerolidyl pyrophosphate in a squalene-synthesizing system from yeast. (b) Nerolidyl-1-(3)H(2) pyrophosphate is not converted to squalene in the presence or absence of farnesyl pyrophosphate. (c) The addition of unlabeled nerolidyl pyrophosphate to incubation mixtures does not alter the relative loss of alpha-hydrogens from farnesyl pyrophosphate during its conversion to squalene. The synthesis of nerolidyl-1-(3)H(2) pyrophosphate is described. Chromatographic methods for the separation of pyrophosphate esters of triprenols and terpenols are included. PMID- 4305713 TI - Phospholipid metabolism during bacterial growth. AB - Haemophilus parainfluenzae incorporates glycerol and phosphate into the membrane phospholipids without lag during logarithmic growth. In phosphatidyl glycerol (PG), the phosphate and unacylated glycerol moieties turn over and incorporate radioactivity much more rapidly than does the diacylated glycerol. At least half the radioactivity is lost from the phosphate and unacylated glycerol in about 1 doubling. The total fatty acids turn over slightly faster than the diacyl glycerol. In phosphatidyl ethanolamine (PE), which is the major lipid of the bacterium, ethanolamine and phosphate turn over and incorporate radioactivity at least half as fast as the phosphate in PG. The glycerol of PE did not turn over in 4 bacterial doublings. In phosphatidic acid the glycerol turns over at one third the rate of phosphate turnover. By means of a modified method for the quantitative recovery of 1,3-glycerol diphosphate from cardiolipin, the phosphates and middle glycerol of cardiolipin were shown to turn over more rapidly than the acylated glycerols during bacterial growth. There is no randomization of the radioactivity in the 1- and 3-positions of the glycerol in the course of 1 doubling. The fatty acids of PG turn over faster than those in PE. In both lipids the 2-fatty acids turn over much faster than the 1-fatty acids. At both positions the individual fatty acids have their own rates of turnover. The distribution of fatty acids between the 1- and 2-positions is the same as in other organisms, with more monoenoic and long-chain fatty acids at the 2-position. The different rates of turnover and incorporation of radioactivity into different parts of the lipids suggest that exchange reactions may be important to phospholipid metabolism. PMID- 4305714 TI - Phosphorus determination in phosphoglycerides from thin-layer chromatograms. AB - Phosphoglyceride phosphorus is readily determined directly on silica gel removed from thin-layer chromatograms, without elution, by a nondigestive procedure with a sulfuric-periodic acid reagent. The method is specific for hydrolyzable phosphoglyceride containing two acid-hydrolyzable groups. Cariolipin reacts only partially, while sphingomyelin, diether lecithin, and phosphonate cephalin fail completely to react. PMID- 4305715 TI - Evaluation of radiotherapy of tumors in the pineal region by ventriculographic studies with iodized oil. PMID- 4305716 TI - Intracranial arteriovenous malformation, pulmonary arteriovenous fistula, and malignant glioma in the same patient. Case report. PMID- 4305717 TI - Alveolar cell (bronchiolar) carcinoma of the lung. PMID- 4305719 TI - [Determination of plasma angiotensinase activity in patients with hypertensive disease and symptomatic renal hypertension]. PMID- 4305718 TI - [Microelement levels and the activity of several enzymes in the myocardium and blood during hemodynamic disorders]. PMID- 4305720 TI - Renal cortical tubular glycogen localization in glycogenosis type II (Pompe's disease). PMID- 4305721 TI - [Hormone therapy in geriatrics]. PMID- 4305722 TI - Cytoplasmic RNA synthesis in adrenal: rapid, selective stimulation by adrenocorticotropic hormone (ACTH). PMID- 4305724 TI - Adenyl cyclase and adenosine 3',5'-cyclic phosphate phosphodiesterase in the receptor tissues of neurohypophysial hormones. PMID- 4305725 TI - Interaction of ouabain with drugs activating lipolysis in vitro. PMID- 4305723 TI - Adenosine 3',5'-monophosphate stimulation of uterine amino acid uptake in vitro. PMID- 4305726 TI - Relation of fatty acid oxidation tgluconeogenesis: effect of pentenoic acid. PMID- 4305727 TI - [On the clinical diagnosis of islet cell adenoma. Clinical experiences and diagnostic procedure in organic hyperinsulism]. PMID- 4305728 TI - [The significance of epileptic seizures in temporal lobe tumors]. PMID- 4305729 TI - The paradoxical dexamethasone reponse phenomenon. PMID- 4305730 TI - [Metabolism of nucleoside diphosphate sugars]. PMID- 4305731 TI - [Radioimmunoassay of plasmatic ACTH]. PMID- 4305732 TI - [Problems posed by the formation of antibodies directed against protein molecules of a molecular weight lower than 5,000]. PMID- 4305733 TI - [The Poland's syndrome]. PMID- 4305734 TI - [Association of antineoplastic agents in the treatment of lung neoplasms. A study of 173 cases]. PMID- 4305736 TI - [Psychosomatic outlooks of asthma]. PMID- 4305735 TI - [Syndrome of vertebral-subclavian collateral circulation. Apropos of a case associated with a right aortic arch]. PMID- 4305737 TI - [Clinical assays of norgestrel associated with ethinyl estradiol]. PMID- 4305738 TI - [Differential diagnosis of venous pain]. PMID- 4305740 TI - [On intrauterine pathology in viral infections]. PMID- 4305739 TI - [Metanephroma]. PMID- 4305741 TI - [Hormonal regulation of blood coagulation (review of the literature)]. PMID- 4305742 TI - Instrumentation for study of neuroregulatory agents and behavior. PMID- 4305743 TI - Respiratory virus vaccines. 8. Field evaluation of trivalent parainfluenza virus vaccine among preschool children in families, 1967-1968. PMID- 4305744 TI - Descriptive epidemiology of interstitial pneumocystic pneumonia. An analysis of 107 cases from the United States, 1955-1967. PMID- 4305745 TI - Lung perfusion in bronchiolo-alveolar carcinoma. A case report. PMID- 4305746 TI - [Electron microscopic study of an intracranial teratoma]. PMID- 4305747 TI - [Preliminary experiences with lymphography with liposoluble contrast medium in cadavers]. PMID- 4305748 TI - [Research on lymphography. I. Structural lymph-node changes during lymphography]. PMID- 4305749 TI - [Research on lymphography. II. Cytological and radiological study after injection of radiopaque substances into the guinea-pig and mouse peritoneum]. PMID- 4305750 TI - [Action of angiotensin II on renal function on man in different conditions of hydration. I. Total body hydration]. PMID- 4305751 TI - [Action of angiotensin II on renal function in man in different conditions of hydration. II. Extracellular hydration]. PMID- 4305752 TI - [The action of angiotensin II on renal function in man in different conditions of hydration. 3. Antidiuresis (spontaneous or induced)]. PMID- 4305753 TI - [Immuno-cytological observations on the localization of ACTH in the pituitary gland of the dog]. PMID- 4305754 TI - [Phosphorus, alkaline phosphomonoesterase and cholinesterase in the maternal and fetal blood at the time of birth]. PMID- 4305755 TI - [Action of thyroxin on glucose-6-phosphatase of the liver, ineffectiveness on phosphofructokinase of the kidney, on phosphoglycerate kinase of the liver and muscle, on aldolase of the kidney, on phosphorylase of the liver, on lactate dehydrogenae of the liver and on glucose-6-phosphatase of the kidney]. PMID- 4305756 TI - [Lack of effect of 64 hours of fasting on the glucose-6-phosphatase, phosphoglucomutase and phosphorylase of the liver in adult sheep]. PMID- 4305757 TI - Bovine para-influenza 3 vaccine studies. AB - A bovine para-influenza 3 modified live virus vaccine was studied in colostrum deprived calves. A single dose of vaccine induced antibody responses and afforded protection against experimental challenge. This was evidenced by reduced clinical disease and virus excretion as compared to unvaccinated control calves. The vaccine virus did not spread from vaccinated calves to contact controls. PMID- 4305758 TI - Immunofluorescent studies of bovine para-influenza 3 virus. I. Cell cultures and experimentally infected hamsters. AB - Immunofluorescent techniques were used to follow the replication of the SF-4 strain of bovine para-influenza 3 (PI-3) virus in Madin-Darby Bovine Kidney (MDBK), secondary bovine kidney (BK), Embryonic Bovine Trachea (EBTr) cell cultures and experimentally infected hamsters. The virus replicated equally well in MDBK and secondary BK cell cultures but less successfully in EBTr cultures. Nuclear fluorescence was not observed in the cell systems studied. Infection was limited to the epithelial lining of the upper respiratory tract, trachea and bronchi of experimentally infected hamsters. Virus was most easily identified in smears prepared from turbinate mucosa suggesting a potential diagnostic technique for use in identifying PI-3 infected animals. PMID- 4305759 TI - Immunofluorescent studies of bovine para-influenza 3 virus. II. Experimentally infected calves. AB - Fluorescent antibody (FA) studies of tissues from three colostrum deprived calves inoculated intranasally with the SF-4 strain of bovine para-influenza 3 (PI-3) virus indicated that these calves developed a mild upper respiratory infection but infected cells were not identified in the lower respiratory tract. Three other calves inoculated intranasally and intratracheally with PI-3 virus developed more severe clinical signs of infection and virus was identified, by FA techniques, in the upper and lower respiratory tract of all three calves and in the spleen of one calf. PI-3 virus was detected in smears of nasal epithelium from five of six calves at some time during the observation period. PMID- 4305760 TI - Equine infectious anemia: preliminary investigation of the complement-fixation test for the demonstration of antibodies and antigen. AB - Clinical field cases of equine infectious anemia were studied and the disease was reproduced experimentally in horses. Attempts were made to adapt the complement fixation test to the detection of antibodies in the serum of infected animals and to the demonstration of antigens in tissue extracts.A moderate complement-fixing antibody response was demonstrated in the serum of horses shortly after primary exposure to the infectious agent. However, this reactivity was of short duration and occurred with normal as well as with infected saline tissue extracts. It was therefore concluded that this reaction was not specific for equine infectious anemia. Possibly it is due to the appearance of auto-tissue antibodies. The value of this reaction in the diagnosis of the infection was limited because of its short duration and absence in chronic infection and following re-exposure to the infectious agent. PMID- 4305761 TI - Antibody production in milk serum after virus instillation of goat mammary gland. 3. Response to herpes simplex virus. AB - Three attempts were made to propagate HERPES SIMPLEX virus in the mammary gland of goats. No active virus resulted. In one instance a marked clinical response was induced in the portion which had been instilled. Repeated instillations induced the synthesis of neutralizing antibody. PMID- 4305762 TI - A serum neutralization test for infectious bovine rhinotracheitis based on colour reaction and cytopathic effects in cell culture. AB - A serum neutralization (SN) test based on a combination of indicator colour change in medium and cytopathic (CP) effect in cells has been devised for the detection of infectious bovine rhinotracheitis antibodies. Serum dilutions of 1:6, 1:18 and 1:54 are made in a medium containing phenol red and are mixed in equal quantities with a suspension of virus containing 100 cell culture infectious doses (CCID(50)) per volume of mixture. The serum-virus mixtures are held in small glass tubes and are covered with a layer of mineral oil. Following a two hour period of incubation at 37 degrees C a quantity of bovine fetal kidney cells is added to each tube to detect the presence of unneutralized virus. After four to six days incubation the results of the SN test may be read by microscopic examination for CP effect by means of an inverted microscope, or by observing the colour of the phenol red. PMID- 4305763 TI - [Effect of a vitamin ADE preparation on spermatic quality and offsprings of bulls used for insemination]. PMID- 4305764 TI - [The role of the factor of the "aging" of dust in the development of experimental silicosis]. PMID- 4305765 TI - [Experimental data on the assessment of the hygienic value of polymorphic transformations of silica in industrial brick]. PMID- 4305766 TI - [Electrodiagnosis of stimulation and electrodiagnosis of detection in peripheral neurogenic disorders. Attempt at correlation]. PMID- 4305767 TI - Glycogen in the normal human testis: a histochemical and histoenzymatic study. PMID- 4305768 TI - The effect of lysine vasopressin and hypothalamic extracts on the rate of corticosterone secretion in rats treated with dexamethasone and pentobarbitone. PMID- 4305769 TI - The delta5-3beta-hydroxysteroid dehydrogenase of bovine adrenal microsomes. PMID- 4305770 TI - The maintenance of lactation in the rabbit after hypophysectomy. PMID- 4305771 TI - Comparative histochemical studies on the inflammatory and-or vitral reaction after infliction of incised wounds in the skin and adipose tissue of guinea-pigs. PMID- 4305772 TI - Ovarian dysfunction associated with an anticonvulsant drug. PMID- 4305773 TI - [Experimental dream deprivation and mental changes]. PMID- 4305774 TI - [Epileptic seizure as the 1st symptom of a brain tumors]. PMID- 4305775 TI - [Rehabilitation of schizophrenics]. PMID- 4305776 TI - [Some considerations on the biologic behavior of cylindroma]. PMID- 4305777 TI - Arterial portography: patterns of venous flow. PMID- 4305778 TI - The many facets of alveolar-cell carcinoma of the lung. PMID- 4305779 TI - [Dynamic tests of the function of the renin-angiotensin-aldosterone system]. PMID- 4305780 TI - [Indices of reactivity of the organism in various degrees of activity of the rheumatic process]. PMID- 4305781 TI - Phosphorylation of protein in liver and kidney mitochondria of the rat. PMID- 4305782 TI - On the inhibition mechanisms of viomycin synthesis by inorganic phosphate. PMID- 4305783 TI - [Study on beta-glucuronidase activity in children. 3. Beta-glucuronidase activity of the blood and tumor tissue in malignant tumor in children]. PMID- 4305784 TI - [On the isolation and properties of desoxyamino sugar from ristomycin]. PMID- 4305785 TI - [General characteristic of flocculants and mechanism of flocculation]. PMID- 4305786 TI - Electron microscopic observations on glioblastoma. PMID- 4305787 TI - [Glucose-6-phosphatase activity of rabbit adrenal glands (biochemical and histoenzymologic study)]. PMID- 4305789 TI - [Action of estrogens on myocardial and kidney NADH2-oxidase systems]. PMID- 4305788 TI - [Action of gestational hormones and corticoids on myocardial respiratory systems]. PMID- 4305790 TI - [Possibilities of use and evaluation of laboratory investigation in diseases of the upper respiratory tract of the chicken]. PMID- 4305791 TI - [Contribution to the peripheral nerve paralysis of the posterior limb in the dog with particular reference to the peroneal nerve]. PMID- 4305792 TI - [Determination and occurrence of fetal vibrio infection caused by the bull in northwestern Germany and suggestions for its control]. PMID- 4305793 TI - [On the determination of testosterone and additional alpha, beta-unsaturated ketosteroids of the C19 series in urine]. PMID- 4305794 TI - [Histochemical changes in the supraoptic nucleus of the rat following metyrapone injection]. PMID- 4305795 TI - [Ultrastructural and enzyme histochemical behavior of the rat pineal body following functional phase change caused by continuous illumination and constant darkness]. PMID- 4305796 TI - [Studies in the field of substances with antiviral activity. Derivatives of 2,4 dioxo-3-oxyiminochromane]. PMID- 4305797 TI - Acetylcholine and related enzymes in the neural lobe and anterior hypothalamus of the rabbit. AB - 1. Acetylcholine (ACh), cholinesterases and choline acetyltransferase (choline acetylase) were estimated in the neural lobe and hypothalamus of the adult male rabbit. Acetylcholine was also estimated in the neural lobes and hypothalami of some other mammals.2. Acetylcholine-like activity was measured by bio-assay using the leech dorsal muscle preparation.3. Characterization experiments indicated that about 90% of the activity measured was due to acetylcholine.4. Mean acetylcholine content in the neural lobe of the rabbit, after extraction with perchloric acid, was 4.38 +/- 0.98 mug/g fresh tissue, and 4.87 +/- 1.53 mug/g in the hypothalamus.5. Acetylcholine was also found to be present, in comparable concentrations, in the neural lobe of man and in the neural lobes and hypothalami of ox, rat and hedgehog.6. Acetylcholinesterase, present in the neural lobe and hypothalamus of the rabbit, hydrolysed 1.74 +/- 0.11 mu-moles of substrate/min/g and 3.78 +/- 0.60 mu-moles substrate/min/g fresh tissue respectively.7. The concentration of butyrylcholinesterase was about one tenth that of acetylcholinesterase in both tissues.8. Choline acetyltransferase present in the neural lobe and in the hypothalamus synthesized 87 +/- 22 mug ACh/hr/g fresh tissue and 378 +/- 149 mug respectively. PMID- 4305798 TI - Transmission from pregnanglionic fibres in the hypogastric nerve to peripheral ganglia of male guinea-pigs. AB - 1. Intracellular records were obtained from ganglion cells of the pelvic plexus of male guinea-pigs.2. The input resistance of cells which responded to intracellular stimulation varied from 40 to 150 MOmega. Slope resistance decreased when the membrane was hyperpolarized. Time constants varied from 5 to 200 msec. Resting membrane potentials ranged from 40 to 70 mV.3. Action potentials in response to direct stimulation were followed by a prolonged phase of after-hyperpolarization.4. A second type of cell was also impaled which did not respond to electrical stimulation. These cells had resting membrane potentials in the range 60-70 mV, input resistances of less than 20 MOmega and time constants of less than 3 msec.5. In most ganglion cells, stimulation of the hypogastric nerve evoked action potentials which were often followed by a secondary phase of depolarization indicating continuing transmitter action.6. Orthodromic responses were generally ;all-or-nothing' and could not be graded with changes in stimulus strength. The latency of orthodromic responses indicated that ganglion cells were innervated by both B and C fibres in the hypogastric nerve.7. Orthodromic responses were blocked by tubocurarine, 5 x 10(-5) g/ml., and dihydro-beta-erythroidine, 10(-5) g/ml.8. Spontaneous, excitatory post synaptic potentials of up to 4.8 mV in amplitude were observed. The frequency of their discharge was greatly increased by repetitive stimulation of the hypogastric nerve.9. The ultrastructure of the pelvic ganglia was studied by electronmicroscopy. Two types of ganglion cell process were observed, fine (0.1 mu) branching tufts thrown up from the soma within the surrounding capsule and longer, thicker (1 mu) extracapsular processes. Synapses were found to occur most frequently between the varicose terminal segments of preganglionic axons and the small intracapsular processes.10. Similarities between the properties of the pelvic ganglia innervated by the hypogastric nerve and those of the parasympathetic division of the autonomic nervous system are discussed. PMID- 4305799 TI - [Study of vectors of Japanese encephalitis in the Maritime Territory]. PMID- 4305800 TI - [Therapeutic indications of indomethacin in pediatrics]. PMID- 4305801 TI - [On the use of some new antibiotics in the therapy of neonatal infections due to gram-negative bacilli. II. Bacteriologic studies]. PMID- 4305802 TI - [The combined action of magnesium fluosilicate and molybdenum in the treatment of experimental caries in the white rat]. PMID- 4305803 TI - [Statistical data concerning the socalled "mixed tumors" of the salivary glands]. PMID- 4305804 TI - Fractionation of equine infectious anemia virus by diethylaminoethyl cellulose chromatography and sucrose density gradient centrifugation. PMID- 4305805 TI - Characteristics of the complement-fixing antigen of equine infectious anemia virus. PMID- 4305806 TI - A perfused vein preparation sensitive to plasma kinins. PMID- 4305807 TI - [Isolation and characterization of chromaffin noradrenaline granules from pig adrenal medulla]. PMID- 4305808 TI - [131-I lymphography of endolymphatic radiotherapy]. PMID- 4305809 TI - [Corticosteroid treatment of children with chronic aspecfic respiratory diseases. 3. Treatment with predniso (lo) ne and body height increase]. PMID- 4305810 TI - Congenital anomalies in children with malignancy. PMID- 4305811 TI - The contribution of adrenergic mechanisms to frequency potentiation and to paired stimulation in guinea pig isolated atrial tissue. PMID- 4305812 TI - Electromyogram suppression during sleep, dream recall, and orientation time. PMID- 4305813 TI - Vertical eye-movement during REM sleep: effects of age and electrode placement. PMID- 4305814 TI - [Contribution of sialography to the study of certain affections of the submandibular gland]. PMID- 4305815 TI - [Surgical treatment of liver tumors]. PMID- 4305816 TI - [The stimulating effect of linol on the formation of group-specific complement fixing antibodies with respect to adenoviruses]. PMID- 4305817 TI - [Two cases of food toxinfection caused by Cl. perfringens type A]. PMID- 4305818 TI - [The use of electron microscopy in association with cytochemistry in the study of bacterial enzymes]. PMID- 4305819 TI - Some effects of vitamin D 3 on collagen synthesis in rachitic chick cortical bone. PMID- 4305820 TI - Toxicologic investigations on a new anti-arrhythmic compound: 1,5-dimorpholino-3 (l-naphthyl)-pentane (DA 1686). PMID- 4305821 TI - Hemodynamic responses to vasopressin before and during infusion of sympathomimetic amines and angiotensin in anesthetized dogs. PMID- 4305822 TI - The combined effect of chlorprothixene and 4-hydroxy-5-fluoropyrimidene on the protein synthesis of various tumour cells. PMID- 4305823 TI - [Influence of the type of aneothesia on blood pressure, heart rate and pressor response to various pharmacodynamic stimulus in dogs]. PMID- 4305824 TI - Indeterminacy, the synapse, the mnemic microstate, and the psyche. PMID- 4305825 TI - Antibodies to Herpesvirus hominis types 1 and 2 in the rabbit. PMID- 4305826 TI - Sleep-induced behavioral response. Relationship to susceptibility to hypnosis and laboratory sleep patterns. PMID- 4305827 TI - The sleep characteristics of the normal aged male. PMID- 4305828 TI - Some correlates of rapid eye movement sleep in the normal aged male. PMID- 4305829 TI - Inhibition by gamma-hexachlorocyclohexane of acetylcholine-stimulated phosphatidylinositol synthesis in cerebral cortex slices and of phosphatidic acid inositol transferase in cerebral cortex particulate fractions. PMID- 4305830 TI - Distribution and properties of CDP-diglyceride:inositol transferase from brain. PMID- 4305831 TI - Biochemical changes in beta, beta'-iminodipropionitrile-treated rat brain and prevention of toxicity by ethionine. PMID- 4305832 TI - A comparative study of brain and liver mitochondria from new-born and adult rats. PMID- 4305833 TI - Ultrastructural localization of inosine-5'-diphosphatase and glucose-6 phosphatase activities in the crayfish vas deferens. PMID- 4305835 TI - The geographic pathology of children's lymphomas. PMID- 4305834 TI - The lymphomas of Brazilian children. PMID- 4305836 TI - Sleep now, pay later. PMID- 4305837 TI - Antilipolytic effect of N6,2'-O-dibutyryl-3' ,5'-adenosine monophosphate in vivo. PMID- 4305838 TI - Exchange coupling in two dimeric copper adenine complexes. PMID- 4305839 TI - [Histopathological and histochemical studies on age-related changes in the intervertebral discs, regional ligaments and vascular systems of the lumbar vertebrae]. PMID- 4305841 TI - Problem solving in arranging for comprehensive home care. PMID- 4305840 TI - [Total gastrectomy. Material from Gjovik fylkessykehus, Nor- way 1936-1967]. PMID- 4305842 TI - [Immunofluorescence in the diagnosis of Bordetella pertussis]. PMID- 4305843 TI - [Radiation-induced sarcoma of the skull]. PMID- 4305844 TI - [Diuresis, natriuresis and urinary aldosterone due to angiotensin II in patients with icterigenous hepatitis]. PMID- 4305845 TI - [Endocrine disorders and Scheuermann's disease]. PMID- 4305846 TI - Growth and regression of rabbit tumours induced by polyoma virus. PMID- 4305847 TI - Responsiveness of enzymes in liver to growth of Novikoff hepatoma. PMID- 4305848 TI - Postoperative gas gangrene. PMID- 4305850 TI - Androgens and growth. PMID- 4305849 TI - Sources of gas gangrene in hospital. AB - Of four cases of postoperative gas gangrene in three hospitals three followed amputation of legs with gangrenous lesions, and one followed gastrectomy. Clostridium welchii was isolated from the wounds and the faeces of each patient; small numbers of Cl. welchii were found on the floors of the theatres where the operations had been performed.Two infections occurred in one hospital on successive days. Typing of strains of Cl. welchii from these patients showed that they were serologically distinct. Further studies suggested that in each of the four cases infection was probably acquired from the patients' intestinal flora, probably through faecal contamination of skin.In 76 patients sampling of the skin with surface contact plates showed occasional heavy contamination of the thighs, groins, and buttocks with Cl. welchii, most of which were present as spores or sporing bacilli; Cl. welchii was more commonly found in patients with incontinence of faeces. Compresses of povidone-iodine applied for 30 minutes were found greatly to reduce the numbers of Cl. welchii, and swabbing with 70% alcohol was effective in some cases; washing with soap and water had no effect on the numbers of Cl. welchii on the skin. PMID- 4305851 TI - Allergic intolerance to tetracosactrin. PMID- 4305852 TI - [Cyclic 3,5-adenosine monophosphate, a probable intermediate of the hypothalamic hormone FRF action]. PMID- 4305853 TI - [Presence of particles with nucleocapside appearance associated with mitochondria in hamster cells transformed by Rous virus]. PMID- 4305854 TI - [Is the rolling cure still up to date? Critical literature review on drug therapy of the stomach and duodenal ulcer]. PMID- 4305855 TI - [Plasma renin activity in peripheral venous blood under various stimulation conditions]. PMID- 4305856 TI - [On the problem of malignant tumors in infancy and childhood]. PMID- 4305857 TI - [Histopathological and histochemical studies of the inclusion bodies in malignant catarrhal fever of cattle]. PMID- 4305858 TI - [First isolation of equine abortion virus from aborted fetus in Western Germany]. PMID- 4305859 TI - [Compounds acting on xanthine oxidase. IV. Thiosemicarbazidebenzoic acids]. PMID- 4305860 TI - [The role of sanitary-preventive measures in reducing the incidence of peripheral nervous system diseases in industrial workers]. PMID- 4305862 TI - The potentiating influence of imipramine on ganglionic effects of catecholamines. PMID- 4305861 TI - The effect of 1, 1-dimethyl-4-phenylpiperazinium iodide on transmission in the superior cervical ganglion of the cat. PMID- 4305863 TI - The effect of atropine and curarine on the time course of the end-palate potential in frog sartorius muscle. PMID- 4305864 TI - Sulfomycins, a series of new sulfur-containing antibiotics. I. Isolation, purification and properties. PMID- 4305865 TI - Molecular and crystal structure of viomycidine. PMID- 4305866 TI - Long biological half-life of vitamin D3 and its polar metabolites in human serum. PMID- 4305867 TI - [Isolation and enzymatic characterization of a brushborder fraction from rat kidney]. PMID- 4305868 TI - [Electron microscopic studies of the junction of tumor and connective tissue in breast carcinoma of women]. PMID- 4305869 TI - St. Louis encephalitis in St. Louis County, Missouri, during 1966. PMID- 4305870 TI - The production of sustained hypertension in dogs by a single transient anoxic episode. PMID- 4305871 TI - [Antiviral properties of streptothricins A, B, C, D, F]. PMID- 4305872 TI - [Effect of the conditions of cultivation on growth and formation of polymyxin M]. PMID- 4305874 TI - [Blood flow through the hypophysis, thyroid gland, and adrenal glands in experimental animals]. PMID- 4305873 TI - [Use of antibiotics in burns in dogs]. PMID- 4305875 TI - [Scleroderma and pregnancy]. PMID- 4305876 TI - Studies on cytochrome oxidase. IV. Optical rotatory dispersion of hematin a. PMID- 4305877 TI - Studies on cytochrome oxidase. V. Factors affecting the optical rotatory dispersion of hematin a. PMID- 4305878 TI - Inhibitory effect of physiological bicarbonate ion levels on the activities of glucose 6-phosphate phosphohydrolase. PMID- 4305879 TI - Characterization and quantitative determination of the hydroxylysine-linked carbohydrate units of several collagens. PMID- 4305880 TI - Reaction of myosin with 1-fluoro-2, 4-dinitrobenzene at low ionic strength. PMID- 4305881 TI - The structure of a glycopeptide from human orosomucoid (alpha-acid glycoprotein). PMID- 4305882 TI - Pyrophosphate binding to and adenosine triphosphatase activity of myosin and its proteolytic fragments. Implications for the substructure of myosin. PMID- 4305883 TI - 220 MHz nuclear magnetic resonance spectra of oxidized and reduced pyridine dinucleotides. PMID- 4305884 TI - Measurement of binding of phosphate ligands to ribonuclease A by direct and competive dialysis rate techniques. PMID- 4305886 TI - Innervation and neural excitation of ventral muscle fibres of the larva of the waxmoth, Galleria mellonella. PMID- 4305885 TI - Chemical and ultrastructural identification of 5-hydroxytryptamine in an identified neuron. AB - The two largest cells in a typical ganglion of the leech (Hirudo medicinalis) nervous system are the colossal cells of Retzius. These cells show a positive chromaffin reaction, and it has been suggested that they contain 5 hydroxytryptamine (5-HT). In this study, the presence of 5-HT in the colossal cells was confirmed by microspectrofluorometry and by thin-layer chromatography and spectrofluorometry of extracts of individually dissected and pooled colossal cell bodies. A single colossal cell body was found to contain, on the average, 3.8 x 10(-10) g (6mM) 5-HT. Electron microscopy shows that the colossal cells are distinguished by the presence of 1000 A granules with irregular, electron-opaque cores. Since the granules are distributed in the same pattern as the 5-HT fluorescence, we have suggested that they contain 5-HT. Furthermore, a chromaffin reaction modified for the electron microscope provides evidence that 5-HT is present in the granule cores. These data can now serve as a basis for further studies on the metabolism, distribution, and function of 5-HT in these identified neurons. PMID- 4305887 TI - The distribution of factor S in the cockroach, Periplaneta americana, and its role in stress paralysis. PMID- 4305888 TI - The morning recall of rapid eye movement period reports given earlier in the night. PMID- 4305889 TI - The effects of hearing one's own voice on dream content: a replication. PMID- 4305890 TI - [Current value of sinusography in the study of chronic maxillary sinusitis (contribution of a new technic based on utilization of an opaque medium in suspension)]. PMID- 4305891 TI - [Epithelioma of the duodenum. Apropos of 9 cases]. PMID- 4305892 TI - [Serological investigations of some aspects of adenoviral endemics in the city of Bucharest]. PMID- 4305893 TI - [Severe complications of introducing into the circulation iodized contrast media. Treatment of one of the most frequent manifestations: collapse]. PMID- 4305894 TI - The influence of ACTH and corticosteroids on the rhythm of adrenocortical function in the 10-day-rebound-phenomenon. PMID- 4305895 TI - Disturbances of plasma cortisol circadian rhythm and of cortisol-ACTH feedback mechanism in central nervous system diseases. PMID- 4305896 TI - Circadian rhythmicity of pituitary adrenal function under resting and stress conditions in rats. PMID- 4305897 TI - [Study of human cases of Venezuelan equine encephalomyelitis. Laboratory diagnosis]. PMID- 4305898 TI - [On the problem of studying the rigidity and flexibility of the human rib]. PMID- 4305899 TI - Growth studies of calcium oxalate in the presence of various ions and compounds. PMID- 4305900 TI - [Influence of butyl-hydroxy-toluene (BHT) on the cytochrome oxidase activity in rat liver]. PMID- 4305901 TI - [Evidence for bicatenoid ribonucleic acids during the viral multiplication cycle by interferon induction in mice]. PMID- 4305903 TI - Effects of adenosine triphosphate and inorganic pyrophosphate on carbon dioxide fixation by isolated spinach chloroplasts. PMID- 4305902 TI - Inhibition of glycolysis in Ehrlich ascites tumor cells incubated with formimino L-glutamate. PMID- 4305904 TI - The present status of the diagnosis and treatment of periphlebitis retinae (Eales' disease). PMID- 4305905 TI - [Experimental vaccination of canaries against pox]. PMID- 4305906 TI - [Pharmacological proprerties of N-(beta-diethylaminoethyl)-2,6 dimethylbenzaldoxime and O-(beta-diethylaminoethyl)-2,6-dimethylbenzaldoxime]. PMID- 4305907 TI - [Antiviral potentials. I. Higher acyl derivatives of thiopurine bases and amantidine; adamantanoyl-derivatives]. PMID- 4305909 TI - [Antiviral potentials. 3. Propoxides and glycidyl esters]. PMID- 4305908 TI - [Antiviral potentials. II. Thiosemicarbazones of substituted acetophenones]. PMID- 4305910 TI - [Antiviral potentials. VII. p-Alkoxybenzenesulfonylbiguandie]. PMID- 4305911 TI - [Some data on the effect of small concentration of silicon dioxide in the air on the health of the child population]. PMID- 4305912 TI - [On the pathogenesis of food poisoning caused by Cl. perfringens, type A]. PMID- 4305913 TI - [Cl. perfringens in food products and in semi-finished products of the canning industry]. PMID- 4305914 TI - [Experiences in improving working conditions at the ore enriching plant of the Zaval'evsk Graphite Combine]. PMID- 4305915 TI - [The organization of, and achievements in the control of quartz dust and silicosis in the People's Republic of Bulgaria]. PMID- 4305916 TI - A soluble factor related to the energy-linked transhydrogenase reaction of Rhodospirillum rubrum chromatophores. PMID- 4305917 TI - Magnetic resonance studies of the interaction of cupric ion with native and modified forms of ribonuclease. PMID- 4305918 TI - A case of mixed salivary tumour of the palate. PMID- 4305919 TI - [Studies on the effect of angiotensin II on catecholamine metabolism in man]. PMID- 4305920 TI - [Peripheral neurological disorders in Fabry's disease (angiokeratoma corporis diffusum universale). Clinical and electron microscopic findings in a case]. PMID- 4305921 TI - [Kidney tumors without macrohematuria]. PMID- 4305922 TI - [Hereditary form of pyloric hypertrophic stenosis in adults associated with somatic malformations]. PMID- 4305923 TI - [Current treatment of juvenile rheumatoid arthritis (juvenile chronic polyarthritis) and Still's syndrome]. PMID- 4305924 TI - [Status epilepticus as the first manifestation of a brain disease]. PMID- 4305925 TI - Blood flow through organs of the rat after an intravenous injection of agniotensin. PMID- 4305926 TI - [Experiences with Terracortil gel in the general practice]. PMID- 4305927 TI - [Peculiarities of the accumulation of neutral red in the organs of the mouse at various intervals after the administration of radiation-protective agents]. PMID- 4305928 TI - [Clinical aspects of intrarenal hemodynamics]. PMID- 4305929 TI - [Organic neurological symptoms in Itsenko-Cushing disease]. PMID- 4305931 TI - [On soluble fractions of the agent of whooping cough]. PMID- 4305930 TI - Fatal varicella generalisata in a child with immunopathy and hereditary neurological syndrome. A report with autopsy, electron microscopy and virus isolation. PMID- 4305932 TI - Melanosis of sheep liver. I. Chemistry of the pigment. PMID- 4305933 TI - Studies on poisoning by Macrozamia communis. II. Effects of modifying agents upon changes induced in the liver by Macrozamia communis. PMID- 4305935 TI - Inactivation of foot-and-mouth disease virus in milk. PMID- 4305934 TI - Catalysis of disulfide interchange in acid media by selenium and tellurium oxy acids. PMID- 4305937 TI - [Influence of the level of plasma angiotensinogen on the variation of plasma renin activity in rats]. PMID- 4305936 TI - [Diagnostic and therapeutic problem posed by uterine chorioadenoma]. PMID- 4305938 TI - [Distribution of pyrimidine oligonucleotides of Herpesvirus hominis DNA and in that of host cells (kidney of fetal sheep)]. PMID- 4305940 TI - [Our experiences with the treatment with ACTH and pyrabutol in lumbo-sciatic syndromes]. PMID- 4305939 TI - The influence of pyrophosphate analogues (diphosphonates) on the precipitation and dissolution. PMID- 4305941 TI - [Topics at the 3d International Congress of Endocrinology: ACTH]. PMID- 4305942 TI - Characteristics of after-care patients. PMID- 4305943 TI - Site of corticotropin-releasing factor (CRF) releasing elements: effect of lesions on ACTH release and adenohypophysial blood flow. PMID- 4305945 TI - The effect of hypertonic solution on the wet weight and contractions of rat uterus and vas deferens. AB - The role of propagated activity in the responses to agonist drugs was studied for the rat uterus and vas deferens. Hypertonic solutions were used to inhibit propagation of activity by shrinking cells. Tissue weight was used to indicate cell volume. Hypertonic solutions after 10 min caused weight loss and reduced the size of contractions in response to submaximal doses of drugs, to KCl, and to external electrical stimulation. Contractions in response to KCl and drugs were diminished to a similar degree in the vas deferens, but in the uterus, drug contractions were depressed much more. Prolonged action of hypertonic solution also differed for the two tissues. In the uterus, weight changes correlated with changes in size of the drug-induced contractions. Uterine contractions reduced in hypertonic solution could be increased by using supramaximal doses of drug. When stimulation was applied to one end of the uterus in a three compartment bath, propagation of spontaneous drug- and KCl-induced contraction occurred, but it was prevented by placing hypertonic solution in the center compartment. An increase of the KCl to 44 mM in the hypertonic solution restored propagation. These experiments yielded no evidence of propagated responses in the rat vas deferens. It was concluded that propagated activity plays a role in drug-induced contractions in the rat uterus but not in the rat vas deferens. Hyperpolarization of shrunken cells might be involved in inhibition of propagation by hypertonic solutions. PMID- 4305946 TI - Inhibitory miniature potentials in the stretch receptor neurons of crayfish. AB - Intracellular microelectrodes inserted into the soma of crayfish stretch receptor neurons record frequent fluctuations of the membrane potential. Time course, amplitude, and interval distribution indicate that they are miniature potentials. At the average resting potential the polarity of the miniature potentials depends on the anion used in the microelectrode: KCl electrodes record depolarizing, K citrate or K(2)SO(4) electrodes, hyperpolarizing miniature potentials. The inhibitory postsynaptic potentials (i.p.s.p.'s) show a similar polarity change. The reversal potentials of i.p.s.p.'s and miniature potentials are equal and within 10 mv of the resting potential, more negative with K citrate (or K(2)SO(4)), less negative with KCl electrodes. Reversal can be accomplished by changing the membrane potential by stretching or by current passing. Injection of Cl(-) into the soma or replacement of external Cl by propionate results in an abrupt increase of the amplitude of the miniature potentials lasting for several minutes. The miniature potentials like the i.p.s.p.'s are reversibly abolished by the application of picrotoxin and gamma-aminobutyric acid. They are not affected by tetrodotoxin, nor by acetylocholine, eserine, or atropine. It is concluded that the miniature potentials represent a spontaneous quantal release of transmitter substance from inhibitory nerve terminals, and that the transmitter substance predominantly increases the Cl(-) permeability of the postsynaptic membrane. The effect of the spontaneously released transmitter on the behavior of the receptor neuron is considerable. The membrane conductance is increased by up to 36% and the excitability is correspondingly depressed. PMID- 4305947 TI - [Tensional regulation of chronic renal insufficiency patients treated by hemodialysis. Roles in constrictive action of angiotensin and renin activity]. PMID- 4305949 TI - [Diagnosis and its problems in neuromuscular diseases, special reference to electromyography--neurogenic or myelogenic]. PMID- 4305948 TI - [Diagnosis and its problems in neuromuscular diseases, with special reference to the differentiation of the components and its abnormalities]. PMID- 4305950 TI - Rehabilitation of the cancer patient. PMID- 4305951 TI - A heart transplantation. 6. Pathological aspects. PMID- 4305953 TI - Primary liver carcinoma in Brisbane. PMID- 4305952 TI - A heart transplantation. 7. Microbiology and antibiotic chemotherapy. PMID- 4305954 TI - Viruses infecting cattle and their role as endogenous contaminants of cell cultures. PMID- 4305955 TI - Satellite viruses, helper viruses, and synergistic action. PMID- 4305956 TI - Primary herpes infection of right second finger. Report of a case. PMID- 4305957 TI - A sensitive electrocardiographic sign in myocarditis associated with viral infection. PMID- 4305958 TI - Familial pituitary dwarfism associated with an abnormal sella turcica. PMID- 4305959 TI - [A comparative assessment of treatment of rickets with D3 videin and an alcoholic solution of vitamin D2]. PMID- 4305960 TI - A phosphatidase produced by Sclerotium rolfsii. PMID- 4305961 TI - Enhancement of responses to chemical carcinogens by nononcogenic viruses and antimetabolites. PMID- 4305963 TI - Bioassays with inbred mice: their relevance for the random-bred animal. PMID- 4305962 TI - Tumor-promoting agents in two-stage carcinogenesis. PMID- 4305966 TI - Hormones in social amoebae and mammals. PMID- 4305965 TI - Electroencephalography. PMID- 4305964 TI - General neurophysiology (bioelectrical aspects). PMID- 4305967 TI - Adenyl cyclase activity in rat pineal gland: effects of chronic denervation and norepinephrine. AB - Adenyl cyclase activity in the pineal gland of rats was determined by measuring the rate of formation of radioactive cyclic 3',5'-adenosine monophosphate from (14)C-labeled adenosine triphosphate. Norepinephrine added in vitro to pineal homogenates enhanced this activity, while denervation of the pineal gland by superior cervical ganglionectomy did not significantly reduce it. The enzyme in these denervated glands was more responsive to the stimulatory effects of norepinephrine. PMID- 4305968 TI - Diphtheria toxin subunit active in vitro. AB - Exposure of diphtheria toxin to dithiothreitol (and similar thiols) resulted in a subunit which was active in catalyzing the adenosine diphosphateribosylation of mammalian aminoacyl-transferase II in the presence of nicotinamide adenine dinucleotide. At the same time there was a marked increase in total ADP ribosylation activity. A molecule which was apparently identical to the derived subunit in size and activity was detected in partially purified preparations of toxin. PMID- 4305969 TI - Immune drug-induced haemolytic anemias. PMID- 4305971 TI - Alteration of a cat small intestine mechanoreceptor response by ionizing radiation. NRDL-TR-68-99. PMID- 4305970 TI - Use of enzyme hydrolysis in the rapid analysis of blood estrogens. PMID- 4305972 TI - Deoxyribonucleotide synthesis and the role of vitamin B12 in erythropoiesis. PMID- 4305973 TI - Viruses in carcinogenesis. PMID- 4305974 TI - An equine genital infection resembling coital exanthema associated with a virus. PMID- 4305975 TI - Hydrogen bonding of vitamin D and egg lecithin in the solid state. A possible molecular role for vitamin D in calcium binding by membranes. PMID- 4305976 TI - Distribution of (Na+-K+)-stimulated ATPase activity in rat intestinal mucosa. PMID- 4305977 TI - Thallium activation of K+-activated phosphatases from beef brain. PMID- 4305978 TI - [Cylindromas and their histogenesis]. PMID- 4305979 TI - [Contribution to the histochemistry of ethmoido-maxillary cylindroma]. PMID- 4305980 TI - [Functional adrenocortical activity and developmental stages of laryngeal carcinoma]. PMID- 4305981 TI - Rhinoviruses of bovine origin. PMID- 4305982 TI - [Intermediate metabolites of glycolysis and adenine nucleotides of rat liver in vivo. 3. Modifications produced by fasting]. PMID- 4305983 TI - [Polygraph study of sleep in swine]. PMID- 4305985 TI - [Buccal ulceration in general medicine with a special study of herpetic and herpetiform lesions]. PMID- 4305984 TI - [Comparison of 4 cytoplasmic enzyme activities of diploid and heteroploid cells cultivated in vitro]. PMID- 4305986 TI - [A simple method for the determination of cortisol in urine and plasma and its application to the assessment of adrenal cortex function]. PMID- 4305987 TI - [Influence of hypophysectomy on ischemic adrenal cortex necrosis in rats]. PMID- 4305988 TI - The effect of cortisone, ACTH, and TSH on mast cell count and on mast cell nonspecific esterase. PMID- 4305989 TI - [Study of adrenal cortex function on the basis of the corticosteroid content of fowl urine]. PMID- 4305990 TI - The antidiuretic activity of the hypothalamus, hypophysis and blood plasma under various states of water metabolism and adrenergic transmission. PMID- 4305991 TI - [Influence of hypophysectomy and pituitary hormones on dextran edema in rats]. PMID- 4305992 TI - [EXOGENOUS AND ENDOGENOUS ACTH activities in native human plasma]. PMID- 4305993 TI - [Enterovirus infections]. PMID- 4305994 TI - Amputation neuroma. A case history. PMID- 4305995 TI - Human skin collagenase: localization and distribution in normal human skin. PMID- 4305996 TI - Human skin collagenase: relationship to the pathogenesis of epidermolysis bullosa dystrophica. PMID- 4305997 TI - Multiple glomus tumors. An ultrastructural study. PMID- 4305998 TI - [Comparison of the action of barbiturates and chloralose on the potentials of the dorsal root]. PMID- 4305999 TI - [Influence of vasomotor tonus on renal circulatory response to angiotensin]. PMID- 4306000 TI - [Action of noradrenaline on the net flow of sodium and permeability to water of frog skin]. PMID- 4306001 TI - [Lasting modifications, induced by somatic stimulation, of the frequency of spontaneous discharge in cortical neurons in rats: difference among the routes assuring primary excitation and prolonged activation]. PMID- 4306002 TI - [Extra-adrenal role of corticotropin in difficulties following adrenalectomy in rabbits]. PMID- 4306003 TI - [Microphysiologic study of cerebral cortex projections on the ventrolateral nucleus in cats]. PMID- 4306004 TI - [The sympathetic ganglion synapse, indicator of the action site of 3 anesthetics]. PMID- 4306005 TI - [Attempt at identification of cells secreting adrenocorticotropic hormone in the distal lobe of the hypophysis of green frogs after administration of a corticostatic substance, metyrapone]. PMID- 4306006 TI - [Effect of somatic sensorial stimulation on the visual field of neurons in the region of the geniculate bodies in cats anesthesitized by chloralose]. PMID- 4306007 TI - [Depolarization of the afferences to the nucleus cuneatus and the nucleus gracilis produced by stimulation of the cerebral stem]. PMID- 4306008 TI - [Presynaptic inhibition of spinal phenomena caused by pilar stimulation using the spines of cats]. PMID- 4306009 TI - [Observations on the behavior of plasma angiotensin activity during congestive cardiac failure]. PMID- 4306010 TI - [An additional report of experiences in the treatment of dyspepsia in infants]. PMID- 4306011 TI - Organization of the histidine-3 region of Neurospora. PMID- 4306012 TI - Deep electrical burn complicated by anuria and pseudomonas septicaemia. PMID- 4306013 TI - Complex synaptic configurations in planarian brain. AB - Complex synaptic configurations which appear to have especial evolutionary and functional significance are shown in the neuropil of the brain of the planarian Dugesia dorotocephala. Some of the endings in these synaptic attachments contain dense core vesicles, suggesting that nonadrenaline or serotonin or both are neurotransmitters at a more primitive phyletic level than reported hitherto. The spatial proximity and connectivity of the synapses suggest modes of action permitting greater functional complexity to the planarian brain than previously supposed. Closely adjacent cellular processes which contain polysomal ribosomes, unusual in the neuropil, suggest synaptic transmission-protein synthesis coupling and a possible role in memory. PMID- 4306014 TI - Neoplastic transformation in vitro of hamster lens epithelium by simian virus 40. AB - Hamster lens epithelium infected with simian virus 40 underwent transformation in vitro and produced tumors when injected into homologous hosts. Undisturbed lens epithelium in man and experimental animals has not been observed to undergo neoplastic change. The virus-induced tumors contained undifferentiated cells that were either polygonal or spindle-shaped. Their origin from lens epithelium seems certain since it is possible to isolate this unique structure free of connective tissue and blood vessels. PMID- 4306015 TI - Observations on current antibiotic usage in the surgical patient. PMID- 4306016 TI - The biochemical basis of adrenal surgery. PMID- 4306019 TI - Immunocytochemistry of acidophil granules of human pituitary. PMID- 4306018 TI - Lipids in cerebrospinal fluid. XII. In multiple sclerosis and retrobulbar neuritis. PMID- 4306020 TI - Electromyography in spinal cord injury. PMID- 4306021 TI - Natural and "induced" sleep. PMID- 4306022 TI - Anterior interosseous nerve palsy. PMID- 4306023 TI - [Synchronous and paradoxical sleep]. PMID- 4306024 TI - [On the problem of pathophysiological mechanisms of narcolepsy, hypersomnia, and conditions of dissociated sleep]. PMID- 4306025 TI - [Some metabolic and regulatory aspects in myasthenia]. PMID- 4306026 TI - The metabolism of pregnenolone and progesterone by cobra adrenal tissue in vitro and the effect of ACTH on product yield-time curves. PMID- 4306027 TI - Suppression by dexamethasone of interrenal activity in adult sockeye salmon (Oncorhynchus nerka). PMID- 4306028 TI - Kinetic and regulatory properties of heart muscle pyruvate dehydrogenase. PMID- 4306029 TI - The effect of flavin isomers and analogues upon the color of bacterial bioluminescence. PMID- 4306030 TI - The bacterial oxidation of vitamin B6. VI. Pyridoxal dehydrogenase and 4 pyridoxolactonase. PMID- 4306032 TI - Electron paramagnetic resonance and circular dichroism studies on milk xanthine oxidase. PMID- 4306031 TI - The bacterial oxidation of vitamin B6. VII. Purification, properties, and mechanism of action of an oxygenase which cleaves the 3-hydroxypyridine ring. PMID- 4306033 TI - The role of molybdenum in xanthine oxidase and related enzymes. Reactivity with cyanide, arsenite, and methanol. PMID- 4306034 TI - Transport of amino acids by confluent and nonconfluent 3T3 and polyoma virus transformed 3T3 cells growing on glass cover slips. PMID- 4306035 TI - New observations on the substrate specificity of cathepsin C (dipeptidyl aminopeptidase I). Including the degradation of beta-corticotropin and other peptide hormones. PMID- 4306036 TI - Periodate oxidation of pseudouridine 5'-phosphate and spectral characterization of the products. PMID- 4306037 TI - Antimicrobial agents. Selection and use. PMID- 4306038 TI - The foetal sheep: morphogenesis of the nervous system and histochemical aspects of myelination. PMID- 4306040 TI - Course of air-borne infection caused by B virus (herpesvirus simiae). I. Lethal inhalation dose of B virus for rabbits. PMID- 4306039 TI - Use of the fluorescent antibody method in the diagnosis of M. parainfluenzae. I. Proliferation of M. parainfluenzae types 1, 2 and 3 in monkey kidney tissue cultures. PMID- 4306041 TI - Lipid composition of human, bovine and sheep pineal glands. PMID- 4306043 TI - Simplified premedication for brain scans and other radioisotope tests. PMID- 4306042 TI - Tetanus toxin and amino acid levels in cat spinal cord. PMID- 4306044 TI - The effect of substrates and inhibitors on the rate of respiration of the infective larvae of Strongyloides ratti Sandground, 1925. PMID- 4306045 TI - Alpha-keto acid dehydrogenase complexes. X. Regulation of the activity of the pyruvate dehydrogenase complex from beef kidney mitochondria by phosphorylation and dephosphorylation. AB - This paper reports the discovery that the activity of the multienzyme pyruvate dehydrogenase complex from beef kidney mitochondria is regulated by a phosphorylation-dephosphorylation reaction sequence. The site of this regulation is the pyruvate dehydrogenase component of the complex. Phosphorylation and concomitant inactivation of pyruvate dehydrogenase are catalyzed by an ATP specific kinase (i.e., a pyruvate dehydrogenase kinase), and dephosphorylation and concomitant reactivation are catalyzed by a phosphatase (i.e., a pyruvate dehydrogenase phosphatase). The kinase and the phosphatase appear to be regulatory subunits of the pyruvate dehydrogenase complex. PMID- 4306047 TI - Donor-acceptor interactions of nitrogen. AB - The nitrogen atoms of organic molecules readily enter into donor-acceptor interactions, giving off an electron from their lone pair. Under favorable conditions the acceptor can form free radicals. S and O atoms behave likewise but less intensely. PMID- 4306046 TI - Incorporation of branched-chain fatty acids into myxoviruses. AB - The incorporation of free fatty acids into myxoviruses was shown, using branched chain fatty acids as molecular markers. The presence of isostearic or phytanic acid was detected by gas-liquid chromatography in the phospholipid fraction of the A(0)/PR8/34 strain of influenza virus. Uptake of free fatty acids into the virus varied from 8 to 11 per cent and was accompanied by a shift in the fatty acid profile. Infected allantoic fluids from eggs treated with branched-chain acids possessed higher hemagglutinin activity when compared to fluids infected under normal conditions. Attempts to detect branched-chain acids in Sendai virus were unsuccessful. Shifts in acyl chain composition persisted after three passages of modified viruses in the absence of branched-chain acids. Force-area curves at an air-water interface revealed the cross-sectional area of branched chain acids to be greater than their straight-chain homologs. It is suggested that hydrophobic interactions can alter the configuration of envelope proteins. Such changes may have an important role in the selection of fragments of influenza viral genome and can conceivably alter viral genotype. PMID- 4306048 TI - Strain MC29 avian leukosis virus release by chick embryo cells infected with the agent. PMID- 4306049 TI - Mammary tumor virus activity in mammary tissues of hormone-stimulated BALB-cfC3H Crgl mice. PMID- 4306050 TI - A technic for the preparation of isolated rat adrenal cells. PMID- 4306051 TI - Prevention of drop in adrenocortical activity in the 7-day-old rat by pretreatment with ACTH. PMID- 4306052 TI - Absence of infectious virus from a line of SV40-transformed human liver cells. PMID- 4306053 TI - Enhancing effect of the murine sarcoma virus (MSV) on the replication of the mouse hepatitis virus (MHV) in vitro. PMID- 4306054 TI - Hypoglycemia and its relationship to histamine sensitization in mice. PMID- 4306055 TI - Enhancement of vesicular stomatitis virus following adsorption with poly-L ornithine. PMID- 4306056 TI - Abortive infection of human cell cultures by a canine adenovirus. PMID- 4306057 TI - Fate of labeled polyoma virus DNA in cell cultures. PMID- 4306058 TI - Nucleoside phosphatase activity in atrial and ventricular myocardium of the rat: a light and electron microscopic study. PMID- 4306059 TI - Oysters and human viruses: effect of seawater turbidity on poliovirus uptake and elimination. PMID- 4306060 TI - Treatment of median sternotomy infection by mediastinal irrigation with an antibiotic solution. PMID- 4306061 TI - Genetic characteristics of poliovirus strains isolated in Poland. PMID- 4306062 TI - Association between autoregulation and pressure dependency of renal vascular responsiveness in dogs. PMID- 4306063 TI - Cutaneous venoconstrictor response to local cooling in the dog. Unexplained by inhibition of neuronal re-uptake of norepinephrine. PMID- 4306064 TI - The biochemical mechanism of selective heat sensitivity of cancer cells. I. Studies on cellular respiration. PMID- 4306065 TI - [Effect of anti-inflammatory compounds on the intensity of inflammatory edema at differet seasons of the year]. PMID- 4306066 TI - [Glycogen content in the liver and muscles and 17-oxycorticosteroid level in the blood of animals during repeated administration of solasodine]. PMID- 4306067 TI - [The present status of physiological dream research]. PMID- 4306068 TI - [Isolation of herpes simplex virus in patients from the city of Rio de Janeiro]. PMID- 4306069 TI - Beta-adrenergic receptors in human platelets. PMID- 4306070 TI - Antigenic relationships among the coronaviruses of man and between human and animal coronaviruses. PMID- 4306071 TI - Density of BAI strain A avian leukosis virus-antibody complexes relative to antigen-antibody ratio. PMID- 4306072 TI - [Effect of culture methods on the biological activities of Bordetella pertussis]. PMID- 4306073 TI - Metaphase figures of rat chromosomes incorporated into mouse cells. PMID- 4306074 TI - Adenoid cystic carcinoma of the uterine cervix. Report of a case and review of 4 cases. PMID- 4306075 TI - The use of plasma cortisol estimations in the management of colitis. PMID- 4306077 TI - Moss-ill--a possible hypocalcaemia of hill ewes. PMID- 4306078 TI - [The function of dreams: psychoanalytic and neurophysiologic connections]. PMID- 4306076 TI - [Role of the mediodorsal thalamic nucleus in temporal lobe seizures--an experimental study]. PMID- 4306079 TI - [Comparative gel immuno-diffusion of Aujeszky and Herpes simplex viruses]. PMID- 4306080 TI - [Tarsal tunnel syndrome]. PMID- 4306081 TI - [Effects on bone of parathyroid hormone]. PMID- 4306082 TI - [Angiofibroma of the conjunctiva (clinical contribution)]. PMID- 4306083 TI - [Cytomorphologic findings on cutaneous histiocytomas]. PMID- 4306084 TI - Effect of ozone. On pyridine nucleotide reduction and phosphorylation of Euglena gracilis. PMID- 4306085 TI - [On the role of para-influenza-3-virus in respiratory enzootic diseases of calves]. PMID- 4306087 TI - Phage 4 and polymyxin B sensitivity of rough strains of classicial V. Cholerae. PMID- 4306086 TI - [Contributions on the differentiation of clostridia. IV. Detection and neutralization of hemolysins in pathogenic clostridia]. PMID- 4306088 TI - [Herpes gestationis]. PMID- 4306089 TI - [Fibroadenomas, phyllode tumors and mammary sarcomas (apropos of 2 cases of progressive sarcomatous transformation of a clinically and histologically initially benign mammary nodule]. PMID- 4306090 TI - Old people leaving hospital. A follow-up of 200 discharged geriatric patients. PMID- 4306091 TI - Immunochemical studies of an organ-specific thermostable antigen of bovine brain. PMID- 4306092 TI - Cytopathic enteroviruses in Delhi area. I. From cases of diarrhoea and healthy controls. PMID- 4306093 TI - The mode of action of an intrauterine contraceptive device. PMID- 4306094 TI - Relationship of viruses to reproductive problems. PMID- 4306095 TI - What's new with bovine respiratory problems. PMID- 4306096 TI - Assessment of cerebral lesions by rapid sequential scintiphotography. PMID- 4306097 TI - Pressure gradients and lymph flow in the canine thoracic duct. PMID- 4306098 TI - The absence of central sympathetic stimulation by low doses of angiotensin in the cat. PMID- 4306099 TI - [Study on parainfluenza 3 virus infection in dromedaries in Chad]. PMID- 4306100 TI - Calcium pyrophosphate dihydrate crystal deposition disease. PMID- 4306101 TI - Chronic idiopathic neutropenia. Treatment with corticosteroids and mercaptopurine. PMID- 4306102 TI - Comparison of total and prostatic fraction serum acid phosphatase levels in patients with differentiated and undifferentiated prostatic carcinoma. PMID- 4306103 TI - Nonepidermoid cancer of the gum. PMID- 4306104 TI - Nonfunctional, nonchromaffin paragangliomas of the retroperitoneum. PMID- 4306105 TI - Extra-uterine Mullerian tumors. A review of the literature and the report of a case. PMID- 4306106 TI - Herpes simplex virus infection and depressive illness. PMID- 4306107 TI - Electrophysiology of the lizard cochlea. PMID- 4306108 TI - Organ specific effect of thioacetamide on liver glycogen. PMID- 4306110 TI - The relationship of intrarenal artery and renal intrapelvic pressure. PMID- 4306109 TI - Preparation of fat cell-"free" rat mammary gland. PMID- 4306112 TI - The discharged mentally ill patient: aftercare and maintenance in the community. PMID- 4306111 TI - [On the possibility of cholangiocholecystography in positive reaction to iodide solution]. PMID- 4306113 TI - The significance of the nerve cell. PMID- 4306114 TI - LDH isozyme activities in subcellular fractions of liver and hepatoma. PMID- 4306115 TI - [Possibilities of the scintigraphic method in the diagnosis of endocranial expanding processes]. PMID- 4306116 TI - [Neuropsychiatric, metabolic and surgical aspects of hyperinsulism due to pancreatic insular adenoma]. PMID- 4306117 TI - [On a rare case of synovial sarcoma with prevailing neurologic symptoms]. PMID- 4306118 TI - [The effect of ACTH and cortisone in combination with microwaves on absorption in the knee joint (experiment)]. PMID- 4306119 TI - [On the state of electrolyte metabolism in schizophrenia]. PMID- 4306121 TI - The mononucleotides. PMID- 4306120 TI - [Longitudinal polygraphic study of sleep in 11 patients with delirium tremens. Physiopathological considerations on "sleep deprivation"]. PMID- 4306123 TI - Functioning beta slet cell tumors. Preoperative tests and surgical approach. PMID- 4306122 TI - Experience with hepatic resection in childhood. PMID- 4306124 TI - Characteristics of nonbacteremic Pseudomonas pneumonia. PMID- 4306125 TI - Reversible respiratory paralysis associated with polymyxin therapy. PMID- 4306126 TI - Treatment of breast cancer with medroxyprogesterone acetate. PMID- 4306127 TI - The neuropathy of Sjogren's syndrome. Trigeminal nerve involvement. PMID- 4306128 TI - Chronic laxative-induced hyperaldosteronism and hypokalemia simulating Bartter's syndrome. PMID- 4306129 TI - NIH clinical staff conference. Burkitt's tumor. PMID- 4306130 TI - Metabolism of arterial tissue and its relation to atherosclerosis. PMID- 4306131 TI - Histochemistry of the development of atherosclerosis. PMID- 4306133 TI - The control of lipid biosynthesis in liver particles. PMID- 4306132 TI - Vascular enzyme activities and susceptibility of arteries to atherosclerosis. PMID- 4306134 TI - Enzymic omega-oxidation: stoichiometry of the omega-oxidation of fatty acids. PMID- 4306136 TI - Susceptibility of Bonnet monkey (M. radiata) kidney cell cultures to human enteroviruses. PMID- 4306135 TI - Great-toe extensor reflexes in the diagnosis of lumbar disc disorder. AB - The tendon reflexes obtainable from the extensors of the great toe require practice to elicit, but have been found particularly valuable in the assessment of lesions affecting the fifth lumbar nerve root, especially compression radiculopathy from disc prolapse. PMID- 4306137 TI - Cytopathic enteroviruses in Delhi area. II. From cases of febrile illnesses with neurological involvements. PMID- 4306138 TI - Japanese encephalitis studies in Vellore, South India. V. Experimental infection and transmission. PMID- 4306139 TI - Pyridine nucleotides: nicotinamide adenine dinucleotide and the cholinergic mechanisms. PMID- 4306140 TI - Binding of ADP-ribose polymer with histone. PMID- 4306141 TI - Isolation and base composition of sites on lambda phage DNA which bind with RNA polymerase of Escherichia coli. PMID- 4306142 TI - Glycine metabolism by rat liver mitochondria. II. Methylene tetrahydrofolate as the direct on carbon donor in the reaction of glycine synthesis. PMID- 4306144 TI - The effect of aldosterone and angiotensin on the intestinal transport of sodium and water in the rat. PMID- 4306143 TI - Glycine metabolism by rat liver mitochondria. 3. The glycine cleavage and the exchange of carboxyl carbon of glycine with bicarbonate. PMID- 4306145 TI - Effect of angiotensin-II-amide on renal function in the clawed toad, Xenopus laevis Daudin. PMID- 4306147 TI - [Hemodynamic modifications during natural sleep in cats]. PMID- 4306146 TI - Studies on the influence of renal nerves on the regulation of aldosterone secretion. PMID- 4306148 TI - [Protection against audiogenic crises in mice by nicotinamide]. PMID- 4306149 TI - [Relation between facilitation and depression at the level of the motor plate in frogs]. PMID- 4306150 TI - [Apropos of the action mechanism of staphylotoxin]. PMID- 4306151 TI - [Centrifugal systems controlling somatosensory afferences of the hindlimb in phalangers]. PMID- 4306152 TI - [Cutaneous vascular capacitance and resistance in humans with normal or interrupted neural routes]. PMID- 4306153 TI - [Elementary activity recorded from the hypothalamus during waking and sleep in rabbits chronically bearing electrodes]. PMID- 4306154 TI - [Histiocytoma. Case of isolated subcutaneous histiocytoma of the breast in an infant]. PMID- 4306155 TI - [Nodular hidradenoma of the left leg]. PMID- 4306156 TI - [Clear-cell sarcoma of the heel]. PMID- 4306157 TI - [Synovial sarcoma of the left pelvis]. PMID- 4306158 TI - [Classification of the Haemophilus species using disks containing X (hemin) and V (DPN) factors]. PMID- 4306159 TI - Crisis in myasthenia gravis. PMID- 4306160 TI - Necrotizing encephalomyelopathy. Report of a case with relapsing polyneuropathy and hyperalaninemia and with manifestations resembling Friedreich's ataxia. PMID- 4306162 TI - Viruses in circulating lymphocytes. PMID- 4306161 TI - A prospective study of the role of cytomegalovirus in post-transfusion mononucleosis. PMID- 4306163 TI - Abnormal fibrinogen synthesis questioned. PMID- 4306165 TI - Radiation-induced free radicals in frozen nitric acid solutions. PMID- 4306164 TI - Abnormal fibrinogen synthesis questioned. PMID- 4306166 TI - Free radicals in gamma-irradiated 2-deoxy-D-ribose: electron spin resonance of single crystals and polycrystalline material. PMID- 4306167 TI - Electron spin resonance of gamma-irradiated single crystals of 9-methyladenine. PMID- 4306168 TI - Effects of head irradiation on paradoxical sleep (EEG afterreaction) in the rabbit. PMID- 4306170 TI - How do viruses cause cancer? New Horizons for Radiologists Lecture. PMID- 4306169 TI - Extralymphatic extravasation of ethiodol during lymphography. PMID- 4306172 TI - [Insulin secretion in normal personsand diabetics]. PMID- 4306171 TI - Histochemical study on plasma cells. PMID- 4306173 TI - [Obtention of M. parainfluenzae 4 (A and B) hemagglutinin utilizable for the hemagglutination inhibition reaction]. PMID- 4306174 TI - [Comparative susceptibility of primary cultures of monkey kidney, human (WI 38) diploid cells and a continuous line of human (AM-57) amnion for the isolation of non-poliomyelitic enteroviruses]. PMID- 4306175 TI - [Blood pressure response to vasoactive substances and blood pressure regulatory mechanisms in pheochromocytoma]. PMID- 4306176 TI - [On the metabolism of silicic acid: I. The silicic acid deficient keeping and nutrition of rats]. PMID- 4306177 TI - [The significance of dust elimination from the lungs in the research of pneumoconiosis]. PMID- 4306178 TI - [On the metabolism of silicic acid. II. The resorption of silicic acid in rats on low and high Si02 concentration in the fodder]. PMID- 4306179 TI - The effect of spermine and oxidized spermine on the enzymic degradation of DNA. PMID- 4306180 TI - Ribonucleic acid-degrading enzymes associated with purified ribosomes from Neurospora crassa mycelia. PMID- 4306181 TI - Incidence of cytomegalic inclusion disease. PMID- 4306182 TI - [Nature of the evoked bioelectrical responses of the associative cortex in their recording from various cortical layers]. PMID- 4306183 TI - [On the synthesis of mediator in the terminal part of adrenergic neurons]. PMID- 4306184 TI - [Morphological analysis of synaptic alterations due to their prolonged activation]. PMID- 4306185 TI - [Inhibition of polysynaptic reflex responses during stimulation of the medullary reticular formation]. PMID- 4306186 TI - [Horizontal cells of the retina as the regulators of synaptic transmission]. PMID- 4306187 TI - [On the role of the corpus callosum in the interahemispheral transmission and bilateral synchronization of seizure activity]. PMID- 4306188 TI - [Correlation between polarization level and velocity of wave impulse transmission in skeletal muscle fibers]. PMID- 4306189 TI - [Metabolism of 6-dehydro-6-chloro-17-alpha-acetoxy-progesterone in rabbits. 1]. PMID- 4306190 TI - [Fractional determination of 4 types of neutral steroid glucuronides (11-deoxy-C 19 steroid, 11-deoxy-C-21 steroid, 11-oxy-C-19 steroid, 11-oxy-C-21 steroid) and 3 types of steroid glucuronides (11-deoxy-neutral steroid, pregnanediol, 11-oxy neutral steroid) by gas-liquid chromatography. 2. Clinical study]. PMID- 4306191 TI - Interpretation of the multiple forms of pig heart lipoamide dehydrogenases. PMID- 4306192 TI - Adenosine diphosphatase in the electron transfer particle. PMID- 4306193 TI - In vitro synthesis of poliovirus ribonucleic acid: role of the replicative intermediate. AB - Poliovirus ribonucleic acid (RNA) polymerase crude extracts could be stored frozen in liquid nitrogen without loss of activity or specificity. The major in vitro product of these extracts was viral single-stranded RNA. However, after short periods of incubation with radioactive nucleoside triphosphates, most of the incorporated label was found in replicative intermediate. When excess unlabeled nucleoside triphosphate was added, the label was displaced from the replicative intermediate and accumulated as viral RNA. It is concluded from this experiment that the replicative intermediate is the precursor to viral RNA. In addition, some of the label was chased into double-stranded RNA. The implications of this finding are discussed. PMID- 4306195 TI - Proteins of vesicular stomatitis virus. I. Polyacrylamide gel analysis of viral antigens. AB - Infection of L cells with vesicular stomatitis virus results in the release, into the cell-free fluid, of four antigenic components separable by rate zonal centrifugation on sucrose gradients. The largest antigens are the infectious (B) particle and a shorter noninfectious, autointerfering (T) particle. The two small antigens are characterized by sedimentation coefficients of approximately 20S and 6S. Treatment of purified B or T particles with sodium deoxycholate results in the release from the particle of a nucleoprotein core which can be purified on sucrose gradient and which has a sedimentation coefficient characteristic of the virus from which it arose. Utilizing purified antigens labeled with (14)C-amino acids during growth, we examined the protein constituents of each antigen by acrylamide-gel electrophoresis. The proteins of B and T particles are identical, each containing one minor (virus protein 1) and three major (virus proteins 2, 3, and 4) proteins, numbered in order of increasing mobility. Virus protein 3 originates from the nucleoprotein core, whereas proteins 2 and 4 come from the coat. The origin of virus protein 1 is not known. The 20S antigen contains a single protein equivalent to virus protein 3, whereas the 6S antigen shows a single protein which is similar to, but probably distinct from, virus protein 2. PMID- 4306194 TI - Structural proteins of vesicular stomatitis viruses. AB - Three major and three minor structural proteins were identified by polyacrylamide gel electrophoresis of purified infectious virions of the Indiana serotype of vesicular stomatitis (VS) virus disrupted with acetic acid, 0.5 m urea, sodium dodecyl sulfate (SDS), and 2-mercaptoethanol. Molecular weights of the six virion proteins were estimated by comparative electrophoretic migration of known marker proteins in the presence of SDS. The following values were obtained: major proteins P6 congruent with 34,500, P5 congruent with 59,500, and P4 congruent with 81,500; minor proteins P3 congruent with 140,000, P2 congruent with 186,000, and P1 congruent with 275,000. P1 did not disaggregate in 8 m urea, but P2 and P3 did. The possibility that P1 is an uncleaved large polypeptide chain could not be ruled out. Six identical protein components were dissociated from Indiana VS virions grown in chick and mouse cells; no cellular proteins could be detected in purified virions. Of six proteins identified in virions of the New Jersey serotype, only the smallest protein (P6) could be distinguished from any of the six proteins of the Indiana serotype on the basis of migration in SDS gels. The defective T particles of Indiana VS virus contained the same six proteins in essentially the same proportions as those of the infectious B virions. Only P6 and P5 could be cleanly separated by preparative gel electrophoresis. PMID- 4306196 TI - Differential inhibition of attachment and eclipse activities of HeLa cells for enteroviruses. AB - Receptor activities of HeLa cells were evaluated for ability to both attach and eclipse enteroviruses after exposure of cells to acid or heat. A modified procedure of acid (pH 1.5) elution of cell-associated virus, as compared with other procedures, provided a general method for the optimal recovery of receptor bound enteroviruses. With this procedure, eclipse of virus operationally was considered to be that amount of virus infectivity which was determined initially to be cell-associated and which was not dissociable from the cells. HeLa cells killed by heating at 56 C for 30 min could not attach or eclipse poliovirus T1, but they attached and eclipsed coxsackieviruses B1 and B3, and they attached echovirus 6 but did not eclipse it. HeLa cells treated at pH 2.5 for 10 min at 2 C could not attach or eclipse poliovirus T1, but they attached coxsackieviruses B1 and B3 and echovirus 6, although these viruses were not eclipsed. These results showed that, within the operational definition of virus eclipse, the eclipse activity of HeLa cells for some viruses can be irreversibly inactivated without impairing the activity of the receptors for attaching these viruses. The data provided additional evidence that HeLa cells possess specific receptors for the different enteroviruses. PMID- 4306197 TI - Immunochemical studies of phospholipids. V. Rabbit antiserum against cardiolipin antigen and its possible application to histochemistry. PMID- 4306198 TI - Response to 4-dimethylaminoazobenzene (DAB) of mammalian cells in culture. PMID- 4306199 TI - In vitro activity of N',N'-anhydrobis (beta-hydroxyethyl) biguanide hydrochloride (ABOB) against parainfluenza viruses. PMID- 4306200 TI - Some observations on the behavior of Culex tritaeniorhynchus summorosus, the prinicipal vector of Japanese encephalitis in Japan. PMID- 4306201 TI - [Cytological findings in rare lung tumors]. PMID- 4306202 TI - [Change in the mineral and protein metabolism in calcified rat tissue in the prolonged administration of hydrocortisone, DOCA and ACTH]. PMID- 4306204 TI - [Comparative assessment of the principle of sorptive adhesion in the extraction of cataracts]. PMID- 4306203 TI - [On the pathogenesis and complex therapy of anemia of the brain]. PMID- 4306205 TI - [Modification of the general condition and water-electrolyte balance in old rats by a vitamin complex]. PMID- 4306206 TI - Solid-cystic hidradenoma: an enzyme histochemical, biochemical, and electron microscopic study. PMID- 4306207 TI - Nucleic acids and protein synthesis in cancer cell mitochondria. II. Amino acid incorporation into proteins of rat liver and hepatoma cell mitochondria. PMID- 4306208 TI - A method of column chromatographic isolation of major phospholipid components on Escherichia coli. PMID- 4306209 TI - [Physiopathological problems posed by myasthenia gravis]. PMID- 4306210 TI - A comparison between methods of calculating skeletal age (Greulich-Pyle). PMID- 4306211 TI - A review of the action of isoniazid. PMID- 4306212 TI - Cavitary bronchiolar carcinoma. A case report. PMID- 4306213 TI - Cross-resistance relationships between capreomycin, kanamycin, and viomycin resistances in tubecle bacilli from paients. PMID- 4306214 TI - Glomus tumour in an African. PMID- 4306215 TI - Theprostaglandins: biologically active lipids with implications in circulatory physiology. PMID- 4306216 TI - Physiological and pathological variations of plasma angiotensin II in man. Correlation with renin activity and sodium balance. PMID- 4306217 TI - Quantitative analysis of the pathophysiology of hypertension. PMID- 4306218 TI - The role of vessel wall reactivity in experimental hypertension. PMID- 4306219 TI - Phosphorylethanolamine and hypophosphatasia. PMID- 4306220 TI - [Antiviral potentials. X. p-Alkoxybenzenesulfonylbiguanides]. PMID- 4306221 TI - [Effect of the rigidity of the molecule of myorelaxants on the curare-like mechanism of action]. PMID- 4306222 TI - [Effect of stimulation of the central m-cholinoreactive structures on the hypophyseal-adrenocortical system]. PMID- 4306223 TI - [Effect of adrenalectomy, adrenaline and ACTH on the antineoplastic action and antimitotic effect of thiophosphamide]. PMID- 4306225 TI - [Transmission of rhythmical impulses through degenerating central synaptic terminals]. PMID- 4306224 TI - [Effect of derivatives of 1-adamantanamide on the system of virus polyoma--cell]. PMID- 4306226 TI - [Tissue adaptation to chronic hypoxia through generations]. PMID- 4306227 TI - [Stimulation of synaptic responses to rhythmical stimulation of phasic and tonic muscle fibers]. PMID- 4306228 TI - Free radical destruction by gamma-irradiation at 77 degrees K. PMID- 4306229 TI - Neuromuscular synapses in the cockroach extensor tibiae muscle. PMID- 4306230 TI - [Current observation on histogenesis of mixed tumor of the salivary gland]. PMID- 4306231 TI - [Studies on nuclease produced by Serratia marcescens]. PMID- 4306233 TI - Oncogenicity of infectious canine hepatitis virus in hamsters. PMID- 4306232 TI - Antigenic relationship among strains of infectious canine hepatitis virus. PMID- 4306234 TI - Characteristics in tissue culture of infectious canine hepatitis virus-induced hamster tumor cells. PMID- 4306236 TI - [Systems theory of homogenous layers. I. Mathematical principles]. PMID- 4306235 TI - [Computation and measurement of the information flow in nerve fibers]. PMID- 4306237 TI - [Poliovirus neutralization test by the microtiter method]. PMID- 4306238 TI - [Leakage of enzymes from the dispersed rat liver cells]. PMID- 4306239 TI - Effects of angiotensin and other peptides on ciliary movement of frog esophagus. PMID- 4306240 TI - Amoebiasis: its meaning and diagnosis. PMID- 4306241 TI - Synthesis of 25-hydroxycholecalciferol, the biologically effective metabolite of vitamin D. PMID- 4306242 TI - Ethanol induced increase of the ratio between hydroxy- and ketosteroids in human pregnancy plasma. PMID- 4306244 TI - [Characteristics of the sex chromatin content of the cells of malignant tumors of the ovaries]. PMID- 4306243 TI - The specificity and mechanism of the Kober reaction. PMID- 4306245 TI - [Experimental tumors of the central nervous system in rabbits]. PMID- 4306246 TI - [The state of the argyrophil fibers in the stroma of cancerous tumors of the breasts]. PMID- 4306247 TI - [A serologic survey of group A and B arboviruses in 6 regions of Azerbaijan]. PMID- 4306248 TI - [A discriminant method for the differential diagnosis of para-influenza and adenovirus diseases in children]. PMID- 4306249 TI - [A comparative study of the cultural properties of human and simian para influenza viruses]. PMID- 4306250 TI - [The influence of specific factors on the intensiveness of phagocytosis by virus infected cells]. PMID- 4306251 TI - [Changes in the level of various microelements in tissue culture infected with canine infectious hepatitis virus]. PMID- 4306252 TI - [The use of gradient centrifugation for the purification of Sendai virus]. PMID- 4306253 TI - [Characteristics of strains of rhinoviruses isolated from patients]. PMID- 4306254 TI - [Reactogenic and immunogenic properties of an attenuated strain of varicella virus]. PMID- 4306256 TI - [The luminescence microscopy method in the diagnosis of para-influenza diseases]. PMID- 4306255 TI - [Infection of mammals with chicken leukosis virus. I. Experience with chicken erythroblastosis virus in Wistar rats]. PMID- 4306257 TI - [Peculiarities of intracranial neoplasms of the aged in diagnosis and treatment]. PMID- 4306258 TI - [Age-induced peculiarities of the course of oxidation processes in the myocardium]. PMID- 4306259 TI - [On the ultrastructure of Paget's disease of the mamillae]. PMID- 4306261 TI - Markers differentiating type 3 parainfluenza virus grown at 25 and 37 C. AB - Serial passage of the 64-2389 strain of type 3 parainfluenza virus in cercopithecus monkey kidney tissue cultures at low temperatures resulted in the selection of a variant which had a higher efficiency of plaque formation at 25 C than the parent line grown at 37 C. The cold variant, unlike the parent strain, plaqued readily at 25 C, and at 37 C it produced significantly larger plaques. Virus titers of the cold variant in hamster lungs were significantly lower and this was probably caused by the stimulation of interferon by the cold variant during the early phase of the infection. The cold variant, like the virus grown at 37 C, also induced the synthesis of interferon late in the infection. Hamsters responded to the intranasal inoculation of each virus line by the development of hemagglutinating-inhibiting antibodies in the sera. PMID- 4306260 TI - Study of delayed hypersensitivity to myxoviruses induced by vaccines. AB - The delayed hypersensitivity response of guinea pigs to Bacillus Calmette-Guerin (BCG) and myxovirus vaccines was investigated by use of the techniques of skin testing and inhibition of macrophage migration. A serum antibody response to the injected vaccines was readily demonstrable. Parainfluenza type 2 virus consistently failed to induce a delayed hypersensitivity state in 15 animals, even with the use of a virus adjuvant emulsion. Respiratory syncytial virus occupied an intermediate position in that positive delayed type skin tests of an erythematous nature were elicited following inoculation, but only two of seven guinea pigs yielded a positive migration inhibition test. In mumps-inoculated animals, skin testing gave rise to erythematous delayed skin reactions which varied from 0 to 20 mm in size. Migration inhibition could be demonstrated in 7 of 21 animals. In almost all guinea pigs inoculated with BCG, large, indurated, erythematous skin reactions were elicited, and inhibition of macrophage migration was readily demonstrated. The degree of skin reactivity was positively correlated with inhibition of macrophage migration. If the skin reaction to a specific antigen exceeded 9 mm of erythema, that antigen also inhibited macrophage migration. Skin testing proved to be the most sensitive indicator of viral hypersensitivity. Migration inhibition was demonstrated only when a greater than 8-mm skin reaction was evoked. This cellular hypersensitivity appeared to be a qualitative phenomenon, the expression of which could be heightened by the use of adjuvant. The applicability and sensitivity of the migration inhibition technique is considered relative to its use for in vitro monitoring of effects of viral vaccine inoculations. PMID- 4306262 TI - Microneutralization test for determination of rhinovirus and coxsackievirus A antibody in human diploid cells. AB - A method for determination of serum-neutralizing antibody titers to rhinovirus type 16 and coxsackievirus type A-4 in human diploid cells (WI-38) grown in Microtiter plates is described. A good correlation was observed when comparing neutralization tests in WI-38 and other cells. The WI-38 Microtiter method is relatively simple and economical. It is suitable for those laboratories which are required to conduct large-scale serological evaluation of antibodies for rhinoviruses and coxsackie A viruses. This system also can be used for cytomegalovirus and varicella-zoster virus, which grow relatively slowly. PMID- 4306263 TI - Minicultures of mammalian cells in a new plastic plate. AB - A new disposable micro tissue culture plate was developed and tested for use in virological procedures. Miniature mammalian cell cultures (minicultures) were grown in these plates. Each plate contained 96 circular cultures in flat wells (7 mm in diameter). Replicate titrations of a number of viruses were performed in various tissues. Excellent reproducibility was demonstrated. Mean infectivity titers determined by miniculture methods were generally within 0.6 log(10)/ml of macro tube titrations. Standard tissue culture assay techniques such as hemadsorption, interference titration, and microneutralization were easily carried out with this method and were very reproducible. Development of this noncytotoxic disposable micro tissue culture plate now permits the routine performance of rapid, reliable, and reproducible tissue culture tests at a very significant reduction in cost and labor. PMID- 4306264 TI - Concentration and purification of herpesviruses (simplex, cytomegalo, and EB) in a zonal ultracentrifuge. AB - By using the BXIV zonal ultracentrifuge rotor, it was possible to efficiently concentrate and partially purify members of the herpesvirus group by pelleting the virus onto a double sucrose cushion. PMID- 4306266 TI - Rabbit intestinal microsomal inorganic pyrophosphate-glucose phosphotransferase: sugar inhibitor specificity. PMID- 4306267 TI - Roles of collagenases and other proteolytic enzymes in the dispersal of animal tissues. PMID- 4306268 TI - Intramitochondrial localization of 5-aminolaevulinate synthase induced in rat liver with allylisopropylacetamide. PMID- 4306265 TI - Purification and properties of the enzyme ATP-sulfurylase and its relation to vitamin A. PMID- 4306269 TI - UDP-D-glucuronate 4-epimerase in blue-green algae. PMID- 4306270 TI - Interconvertible forms of muscle phosphorylase phosphatase. PMID- 4306271 TI - The role of the reticular activating system in the regulation of ACTH secretion. PMID- 4306272 TI - Differential effects of sodium butyrate and physostigmine upon the activities of para-sleep in acute brain stem preparations. PMID- 4306273 TI - 2',3'-cyclic nucleotide 3'-phosphohydrolase in the brain of the "Jimpy" mouse, a mutant with deficient myelination. PMID- 4306274 TI - Developmental patterns in the central nervous system of birds. V. Cerebral electrical activity, forebrain function and behavior in the chick at the time of hatching. PMID- 4306275 TI - Inhibition of transmission in the recurrent inhibitory pathway to motoneurones. PMID- 4306276 TI - A study on the effect of Flagyl on Entamoeba histolytica. PMID- 4306277 TI - Enzymes of protein and phosphate catabolism in rat bone. I. Enzyme properties in normal rats. PMID- 4306279 TI - The part played by the extracellular components (collagen and albumin) in the decrease in reactivity of adipose tissue in old rats. PMID- 4306278 TI - Enzymes of protein and phosphate catabolism in rat bone. II. Changes in vitamin D deficiency. PMID- 4306280 TI - Changes in the structure of collagen in the direction of ageing in relation to decreased lipomobilization in rats. PMID- 4306281 TI - Comparative studies on the sensitivity of some of the methods of complement fixation test commonly used for typing of foot and mouth disease virus. PMID- 4306282 TI - Metabolic interlock. Regulatory interactions exerted between biochemical pathways. PMID- 4306283 TI - Spectrophotometric titration of ferredoxins and Chromatium high potential iron protein with sodium dithionite. PMID- 4306284 TI - Structure of cell wall lipopolysaccharide from Salmonella typhimurium. I. Linkage between o side chains and R core. PMID- 4306285 TI - Regulation and mechanism of phosphoribosylpyrophosphate synthetase. I. Purification and properties of the enzyme from Salmonella typhimurium. PMID- 4306286 TI - Studies of the electron transport chain of extremely halophilic bacteria. II. Salt dependence of reduced diphosphopyridine nucleotide oxidase. PMID- 4306287 TI - Lactate dehydrogenase of lobster (Homarus americanus) tail muscle. I. Physical and chemical properties. PMID- 4306288 TI - Lactate dehydrogenase of lobster (Homarus americanus) tail muscle. II. Kinetics and regulatory properties. PMID- 4306289 TI - Enzymatic synthesis of deoxyribonucleic acid. XXVII. Chemical modifications of deoxyribonucleic acid polymerase. PMID- 4306291 TI - The properties of glycogen synthetase and regulation of glycogen biosynthesis in rat brain. PMID- 4306290 TI - Enzymatic synthesis of deoxyribonucleic acid. 28. The pyrophosphate exchange and pyrophosphorolysis reactions of deoxyribonucleic acid polymerase. PMID- 4306292 TI - Electron spin-echo studies of relaxation processes in high-spin ferrimyoglobin. PMID- 4306293 TI - The separation of herpes virus-specific antigens by polyacrylamide gel electrophoresis. PMID- 4306294 TI - The preparation of 'monoprecipitin' antisera to herpes virus specific antigens. PMID- 4306295 TI - The binding of DNA polymerase to polyoma DNA. PMID- 4306296 TI - Comparison of the antiviral activity in vitro of some non-steroidal anti inflammatory drugs. PMID- 4306297 TI - Biological markers for differentiation of herpes-virus strains of oral and genital origin. PMID- 4306298 TI - Specific tumour antigen induced by chick embryo lethal orphan (CELO) virus. PMID- 4306299 TI - [Cytochemical study on the pathological synovial fluid]. PMID- 4306300 TI - Immunochemical characterization of plaque mutants of simian virus 40. AB - Analysis of large and small plaque mutants of simian virus 40 using antisera prepared against each has revealed quantitative and possibly qualitative antigenic differences for each plaque type. A sensitive micro radioisotope precipitation test permitted evaluation of immunochemical similarities and differences of capsid antigens by inhibition of precipitation. PMID- 4306302 TI - Contrasting effects of polycations on plaquing efficiency of encephalomyocarditis virus variants. AB - Polycation treatment of L cell monolayers affected plaquing efficiency of both the r(+) and r variants of the encephalomyocarditis virus. Plaque formation by r(+) variant was decreased markedly by three structurally different types of synthetic basic polymers, diethylaminoethyl dextran, hexadimethrene (polybrene), and basic polyamino acids. In contrast, these same substances increased substantially the number of plaques formed by the r variant. The effect on the two variants was observed when polycations were applied to the cells before or simultaneously with the introduction of virus. The molar concentration and size of the polymer proved important. Thus, basic polyamino acids of low molecular weight were significantly more inhibitory for the r(+) variant than were those of high molecular weight. On the other hand, plaquing efficiency of the r variant was increased by relatively large polyamino acids, but not by polymers of small size. Basic polyamino acids inhibited r(+) plaque formation to a greater degree at low than at high pH values. However, plaquing efficiency of the r variant in polycation-treated cultures was not affected by changes in pH. Basic polymers appear to bind to cell membranes and affect either attachment or uptake of the viruses. The evidence suggests that the substances influence by different mechanisms the interaction of the r(+) and r variants with cells. PMID- 4306301 TI - Simian virus 40 deoxyribonucleic acid replication. I. Effect of cycloheximide on the replication of SV40 deoxyribonucleic acid in monkey kidney cells and in heterokaryons of SV40-transformed and susceptible cells. AB - Infectious deoxyribonucleic acid (DNA) was extracted from green monkey kidney (CV 1) cultures at various times after the cultures were infected with simian virus 40 (SV40) at input multiplicities of 0.01 and 0.1 plaque-forming unit (PFU) per cell. A pronounced decrease in infectious DNA was observed from 3 to 16 hr after virus infection, suggesting that structurally altered intracellular forms may have been generated early in infection. Evidence is also presented that SV40 DNA synthesis requires concurrent protein synthesis. DNA replication was studied in the presence and absence of cycloheximide in: (i) SV40-infected and uninfected cultures of CV-1 cells; (ii) cultures synchronized with 1-beta-d arabinofuranosylcytosine (ara-C) for 24 to 30 hr prior to the addition of cycloheximide; and (iii) in heterokaryons of SV40-transformed hamster and susceptible monkey kidney cells. DNA synthesis was determined by pulse-labeling the cultures with (3)H-thymidine at various times from 24 to 46 hr after infection. In addition, the total infectious SV40 DNA was measured. Addition of cycloheximide, even after early proteins had been induced, grossly inhibited both SV40 and cellular DNA syntheses. The activities of thymidine kinase, DNA polymerase, deoxycytidylate deaminase, and thymidylate kinase were measured; these enzyme activities remained high for at least 9 hr in the presence of cycloheximide. SV40 DNA prelabeled with (3)H-thymidine before the addition of cycloheximide was also relatively stable during the time required for cycloheximide to inhibit further DNA replication. PMID- 4306303 TI - Interactions between Sendai virus and human erythrocytes. AB - Concentrated Sendai virus, when adsorbed to erythrocytes at 4 C, caused invaginations in the plasma membrane. Following elevation of the temperature to 37 C, the plasma membrane became fused with the viral envelope before dissolution of the virions and rupture of the cells. Cell lysis was accompanied by rapid and total loss of hemoglobin to the extracellular space. Following aqueous pyridine extraction, the hemoglobin-free ghosts remaining were found to be devoid of N acetylneuraminic acid and to have solubility properties different from those of normal erythrocyte ghosts. By the action of viral neuraminidase, bound N acetylneuraminic acid was also liberated from purified virus receptor substance whose electrophoretic mobility was thereby substantially reduced. Cu(++) selectively inhibited hemolysis and neuraminidase without interfering with hemagglutination and attachment. Neuraminidase appeared to be essential for Sendai virus hemolysis; viral particle size may also be a critical factor in this process. PMID- 4306304 TI - Formation of viral ribonucleic acid and virus in cells that are permissive or nonpermissive for murine encephalomyelitis virus (GDVII). AB - GDVII virus growth in BHK-21 cells, a permissive host for the virus, resembled productive infections with other picornaviruses. Virus yields ranged from 100 to 600 plaque-forming units (PFU)/cell. Virus replication in HeLa cells, a nonpermissive host for GDVII virus, was characterized by virus yields of only 0.1 to 5 PFU/cell. Similar low yields of virus have been obtained from HeLa cells at all multiplicities of input up to 6,000 per cell. The progeny particles from HeLa cells were, like the infecting particles, restricted in the HeLa cell host. Despite the great difference in final yields of virus from BHK-21 and HeLa cells, the times when maximal yields were reached were similar. GDVII virus stock grown in BHK-21 cells was designated HeLa(-). A variant of GDVII virus which is capable of extensive growth in HeLa cells was obtained. This variant, designated HeLa(+) GDVII virus, was passaged serially in HeLa cells. Virus yields of 50 to 150 infective virus particles per cell were obtained from infection of HeLa cells with HeLa(+) GDVII virus. The major species of HeLa(+) virus-specific ribonucleic acid (RNA) produced was single stranded and sedimented with an S value of 35S. The rate of accumulation of HeLa(+) virus-specific RNA in HeLa cell cultures was about four times that of HeLa(-) RNA. The amount of virus-specific HeLa(+) RNA formed in HeLa cells was several-fold greater than that of HeLa(-) RNA. With HeLa(-) parent GDVII virus undergoing productive replication in BHK-21 cells or abortive replication in HeLa cells, the major species of virus-specific RNA produced was single stranded and sedimented with an approximate S value of 35S. The amount of HeLa(-) virus-specific RNA extracted from BHK-21 cells was several fold greater than the amount obtained from HeLa cells. PMID- 4306306 TI - Titration and extensive serial passages of Yaba virus in vitro. PMID- 4306305 TI - Oral and genital bovine herpesviruses. PMID- 4306307 TI - Replication of human adenovirus in green monkey kidney cells transformed by adeno 7-SV40 hybrid virus. PMID- 4306308 TI - Immunochemical and biochemical studies of fungi. 13. On the galactomannans isolated from mycelia and culture filtrates of several filamentous fungi. PMID- 4306309 TI - Electron microscopic observations of the cells infected with varicella-zoster virus. PMID- 4306310 TI - Abbott's "AA"; admission by appointment. PMID- 4306311 TI - [Study on laryngeal cancer among women. 2. Case of laryngeal cancer complicated by ovarian arrhenoblastoma]. PMID- 4306312 TI - Changes in daily urinary excretion of follicle-stimulating and luteinizing hormones caused by ethinyl-estradiol and conjugated equine estrogens (Premarin) in low doses. PMID- 4306313 TI - [Participation of host factors in induction of leukemia using viruses and radiation]. PMID- 4306314 TI - [Experimental bases of the pathophysiology of the renin-angiotensin system]. PMID- 4306315 TI - [Plasma renin activity and pressure-raising angiotensin dosage]. PMID- 4306316 TI - [Comparative studies on the decomposition of angiotensin II and angiotensin II amide by peptidases of human plasma]. PMID- 4306317 TI - [Renin-angiotensin-aldosterone system in blood pressure regulation disorders]. PMID- 4306318 TI - [Experimental amebiasis. Finding of a pathogenic type of E. histolytica in immune tolerant white mice]. PMID- 4306320 TI - Malignant melanoma: treatment by endolymphatic radio-isotope infusion. PMID- 4306319 TI - Nature of anaemia in rheumatoid arthritis. XI. Changes in iron metabolism induced by the administration of corticotrophin. PMID- 4306321 TI - [In vivo effect of streptonigrin on the ultrastructure of Yoshida ascites hepatoma]. PMID- 4306322 TI - Effects of somatosensory stimulation on dream content. PMID- 4306323 TI - Clostridium perfringens meningitis. Report of a case with neuropathological observations. PMID- 4306324 TI - Growth of paramyxoviruses in anucleate cells. PMID- 4306325 TI - [Quartz and P204 effect on the oxygen consumption of isolated alveolar macrophages of guinea pigs under special experimental conditions (teflon film method)]. PMID- 4306326 TI - Reconstitution of respiratory control of succinate oxidation in submitochondrial particles. PMID- 4306327 TI - Adenyl cyclase activity in human platelets. PMID- 4306328 TI - Significance of the so-called J-shaped sella in the diagnosis of intracranial aneurysm. PMID- 4306329 TI - Thermolability of growth promoting substances in the culture medium of Entamoeba histolytica. PMID- 4306330 TI - [Study of the action of monoperphthalic acid on yeast ribonucleotides and ribonucleic acids]. PMID- 4306331 TI - [The mechanism of action of thyrotropic hormone]. PMID- 4306332 TI - [Action of insulin on the plasma membrane]. PMID- 4306333 TI - [Control exercized by adrenalin on turnover time of ATP and ADP at the level of glycolysis and oxidative phosphorylations in muscle]. PMID- 4306334 TI - Metanephrine: cardiovascular responsiveness in normotensive and renal hypertensive dogs. PMID- 4306335 TI - Effect of vitamin D2 on hormone-stimulated lipolysis in vitro. PMID- 4306336 TI - [Adenoid-cystic carcinoma of the Bartholin's gland]. PMID- 4306337 TI - An electrophysiological and psychophysical study of two forms of congenital night blindness. PMID- 4306338 TI - Recurrence of herpes simplex virus in rabbit eyes: results of a three-year study. PMID- 4306339 TI - Pulmonary function tests in a Sheffield steel works. PMID- 4306341 TI - Studies of PPLO infection. V. Inhibition of lymphocyte mitosis and antibody formation by mycoplasmal extracts. AB - Extracts of five arginine-utilizing mycoplasmas inhibit PHA-induced lymphocyte mitosis, while extracts of five glucose-utilizing mycoplasmas do not. Evidence is presented supporting the view that the inhibitory factor is the enzyme arginine deiminase. This enzyme inhibits the reactions of human lymphocytes to antigens as well as PHA, and the secondary production of antibody by rabbit lymph node fragments in vitro. Addition of enzyme to the cells several days after the initial mitotic or antigenic stimulus reduces, but does not abolish, further cellular activity. The production of serum proteins by hepatoma cells is totally unaffected by the mycoplasmal extract. It is concluded that arginine is an essential amino acid for the small lymphocyte, but not for the transformed cell nor for a number of other cell types. Suggestive evidence has been obtained that other enzymes similarly affect lymphocyte reactions. PMID- 4306342 TI - Data on the distribution of Clostridium perfringens in the environment of man. Communication 1. PMID- 4306340 TI - Comparison of reactions of antibodies to rat collagen and to rat kidney in the basement membranes of rat renal glomeruli. AB - By in vivo and in vitro methods of immunofluorescence, antibody to rat collagen and to rat kidney show the same regular, linear fluorescence following the outlines of the renal glomerular capillaries. Absorption of each antiserum with its homologous antigen completely removed the antibody for immunofluorescence, while absorption with the heterologous antigen had no effect. The nephrotoxicity persisted in the anti-kidney serum absorbed with collagen. By pretreatment of frozen normal rat kidney sections with various enzymes followed by immunofluorescence, it was shown that trypsin and hyaluronidase had no effect on the subsequent fluorescence of either antibody; papain reduced the fluorescence; and pepsin and Pronase acted on both antigens so that no fluorescence was present. One preparation of neuraminidase, derived from V. cholerae, reduced fluorescence of both antibodies in some preparations, but the same enzyme derived from influenza virus or C. perfringens had no effect on either. Collagenase completely prevented fluorescence of the antibody to collagen and had no effect on that to rat kidney. The findings in this study show that the antibody to collagen is directed to collagen in rat renal glomerular basement membranes and that the antibody to rat kidney reacts with some antigen other than collagen in these membranes. PMID- 4306343 TI - Variability of variola and alastrim virus. PMID- 4306344 TI - [On the quantitative analysis of barbiturates using thin-layer chromatography]. PMID- 4306346 TI - [Studies on myocardial metabolism in the ischemic heart. II. Studies by the electron spin resonance method]. PMID- 4306345 TI - The action of phenylmethylsulfonyl fluoride on human acetylcholinesterase, chymotyrpsin and trypsin. PMID- 4306347 TI - Amino acid analysis after degradation of angiotensinII by rat kidney lysosomes. PMID- 4306348 TI - [Hyperadrenocorticism]. PMID- 4306349 TI - [Hyperadrenocorticism]. PMID- 4306350 TI - [Hyperadrenocorticism--evaluations of the methods of ACTH extraction from the tissue]. PMID- 4306351 TI - [Infrared thermometry in diagnosis of breast diseases]. PMID- 4306353 TI - An identification of the radical giving rise to the light-induced electron spin resonance signal in photosynthetic bacteria. PMID- 4306354 TI - ESR studies of chlorophyll one-electron photochemistry in solution: kinetics of reversible quinone reduction and general redox mechanisms. PMID- 4306352 TI - The possible role of glycoproteins in neural function. PMID- 4306355 TI - Results of treatment of myocardial infarction accompanied by shock in relation to drugs applied. PMID- 4306356 TI - Experimental studies of the neomycin-induced malabsorption syndrome. PMID- 4306357 TI - Alcohol dehydrogenase: in vitro studies of its relationship to hepatic lipid synthesis in the rat. PMID- 4306358 TI - [Outbreak of infectious anemia among horses on a farm--an epidemiological experiment]. PMID- 4306359 TI - [In memoriam Henry H. Dale (1875-1968)]. PMID- 4306360 TI - [Alveolar proteinosis and pulmonary cytomegalic inclusions associated with thymic alymphoplasia]. PMID- 4306361 TI - [Demonstration of a cochicine-like effect in poliovirus infected tissue culture cells after interruption of virus reproduction with guanidine]. PMID- 4306362 TI - A new influenza A virus infection in turkeys. IV. Experimental susceptibility of domestic birds to virus strain turkey-Ontario 7732-1966. PMID- 4306363 TI - A new influenza A virus infection in turkeys. V. Pathology of the experimental disease by strain turkey-Ontario 7732-66. PMID- 4306364 TI - [The infection of mice with the mouse hepatitis virus (MHV 3). I. Analysis of several experimental data from the view point of the single hit theory]. PMID- 4306365 TI - Virus growth inhibition by ethidium chloride and other dyes. PMID- 4306366 TI - Properties of the CV1 strain of vaccinia virus. I. Studies in cell culture. PMID- 4306367 TI - The epizootiological importance of foot-and-mouth disease carriers. II. The carrier status of cattle exposed to foot-and-mouth disease following vaccination with an oil adjuvant inactivated virus vaccine. PMID- 4306368 TI - Virulence, adsorbability, and antigenicity of foot-and-mouth disease virus selected by adsorption with homogenized mouse kidney. PMID- 4306369 TI - Viral susceptibility of some in vitro cultured tissues from baboons (Papio sp.). PMID- 4306370 TI - Isolation of adenoviruses from baboons (Papio sp.) with respiratory and enteric infections. PMID- 4306371 TI - Cytological studies on cytomegalovirus infected mouse cells. PMID- 4306372 TI - The development of an attenuated foot-and-mouth disease virus vaccine by modification and cloning in tissue cultures of BHK21 cells. PMID- 4306373 TI - Transformation of hamster embryo fibroblasts by SV40-adeno 7 hybrid virus and the properties of the transformed cells. PMID- 4306375 TI - Physicochemical studies of equine infectious anemia virus. II. Sensitivity of the virus to trypsin. PMID- 4306374 TI - Physicochemical studies of equine infectious anemia virus. I. Buoyant density of the virus. PMID- 4306376 TI - [Morpho-biologic aspects of Zollinger-Ellison syndrome]. PMID- 4306377 TI - [Clinical aspects of Zollinger-Ellison syndrome]. PMID- 4306378 TI - Influence of 6-azauridine on the multiplication of the parainfluenza 3 virus. PMID- 4306379 TI - [Poliomyelitis in Cambodia. Epidemiologic data apropos of a recent epidemic]. PMID- 4306380 TI - [Antigenic study of 6 strains of Entamoeba histolytica by indirect immunofluorescence. Results compared, for 1 of the strains, of smears on slides and frozen sections]. PMID- 4306381 TI - [Manifestation of specificity observable by detection of phosphohydrolases in fixed rodent testicular tissue]. PMID- 4306382 TI - Studies on L-ascorbic acid derivatives. II. L-Ascorbic acid 3-phosphate and 3 pyrophosphate. PMID- 4306383 TI - [The effect of hypophysectomy on renal function undergoing compensatory hypertrophy]. PMID- 4306384 TI - [Neuronal mechanisms of cortico-spinal motor systems]. PMID- 4306385 TI - [Role of segmental interneurons in cross inhibition of the flexor reflex]. PMID- 4306386 TI - [Time relations of the discharges of motoneurons innervating different muscles in man]. PMID- 4306387 TI - [Climacteric complaints in internal medical practice. Results of a treatment with conjugated estrogens]. PMID- 4306388 TI - Central and reflexogenic cardiovascular actions of prostaglandin E1. PMID- 4306389 TI - Data transmission between neurons. PMID- 4306390 TI - [Early experiments on the changes in cells and chromosomes in cultures of cells of human tissue and of monkey kidneys following treatment with various additives]. PMID- 4306391 TI - [Possibilities of drug therapy of gynecologic malignancies]. PMID- 4306393 TI - Viremia and immunological responses in horses infected with equine infectious anemia virus. PMID- 4306392 TI - [Unusual course of cranial arteritis]. PMID- 4306394 TI - [On lymph flow and lymph composition of the dog liver as a function of hemodynamics]. PMID- 4306395 TI - [Lipolysis on isolated fat cells of obese mice]. PMID- 4306396 TI - [Influence of theophylline and imidazole on the effect of histamine on the guinea pig heart]. PMID- 4306397 TI - [Studies on the site of application of 5-methylisoxazole-3-carboxylic acid in the lipolytic system of adipose tissue]. PMID- 4306398 TI - [Antagonistic influencing of circulatory reactions following angiotensin and vasopressin in the anesthetized dog]. PMID- 4306399 TI - [Postsynaptic effect of hemicholinium no. 3 on the guinea pig atrium]. PMID- 4306401 TI - [On complications in the aerosol method of vaccinating birds against pseudoplague]. PMID- 4306400 TI - [The use of orange-red luminescing serum in the rapid diagnosis of avian variola diphtheria]. PMID- 4306402 TI - [On renovasography]. PMID- 4306404 TI - Effects of experimental renal hypertension on aldosterone biosynthesis by rat adrenal tissue. PMID- 4306403 TI - Semiquantitative estimation of urinary pregnanetriol, pregnanetriolone and tetrahydro S in the investigation of adrenocortical function. PMID- 4306405 TI - A radio-bioassay for corticotrophin. PMID- 4306407 TI - Clostridium perfringens food poisoning. PMID- 4306406 TI - [Experimental study on the acute toxicity of a food additive, Syloid (amorphous silica) administered orally]. PMID- 4306408 TI - [Histochemical enzyme-examination of normal and pathological mucous membranes of human maxillary cavity]. PMID- 4306409 TI - [Enzyme activity of unspecific phosphomonoesterase in tonsils, adenoids and lymph nodes]. PMID- 4306410 TI - [An in vitro test for the determination of hemagglutinating properties of various antibiotics as well as of antibiotics-lysozyme interactions]. PMID- 4306411 TI - [Differential diagnosis of solitary structures in the breast]. PMID- 4306412 TI - Effect of veratrine and tetraethylammonium on hippocampal homosynaptic and heterosynaptic post-tetanic potentiation. PMID- 4306413 TI - [On the problem of application of the method of foam flotation for the concentration of enteroviruses in water]. PMID- 4306414 TI - Relationship between uridine kinase activity and rate of incorporation of uridine into acid-soluble pool and into RNA during growth cycle of rat hepatoma cells. PMID- 4306415 TI - Neuroglia and the myelin-bearing cell: a symposium. Immunological factors in experimental allergic encephalomyelitis and multiple sclerosis as revealed by cultures of mammalian nerve tissue. PMID- 4306416 TI - [Anterior pituitary function test]. PMID- 4306417 TI - [Adrenal cortex function tests and their interpretation]. PMID- 4306419 TI - [ACTH]. PMID- 4306418 TI - [Pancreatic function tests]. PMID- 4306420 TI - [Angiotensin]. PMID- 4306421 TI - [Renin]. PMID- 4306422 TI - Studies on morphological precursors of the mouse hepatoma induced with o aminoaxotoluene. I. Approach to the methodology. PMID- 4306423 TI - [Clinical picture and prognosis of liver cirrhosis]. PMID- 4306424 TI - [Clinicopathological conference No 147. Chief complaint: dysphoria of the cardiac space and weight loss]. PMID- 4306425 TI - [Prevention of pancreatic fistulas after exeresis of a langerhansian adenoma. Application to the pancreatic biopsies]. PMID- 4306426 TI - [Insulin-secreting langerhansian beta-cell tumor in a woman with diabetes mellitus. Case report and literature review]. PMID- 4306427 TI - Physiological aspects of the motor system. PMID- 4306429 TI - Peripheral neuropathies following the administration of heterologous immune sera. A critical evaluation. PMID- 4306428 TI - Multiple aneurysms in a case of acromegaly. PMID- 4306430 TI - [Pseudopolypoid esophageal cancer or "the story of a ghost tumor"]. PMID- 4306431 TI - [Metastatic neoplastic stenosis of the middle 3rd portion of the esophagus]. PMID- 4306432 TI - [Cancer of the esophagus and hiatal hernia]. PMID- 4306433 TI - [Degenerated ulcer and ulcerated cancer of the stomach]. PMID- 4306434 TI - [Apropos of a rare stomach tumor: carcinoid tumor]. PMID- 4306435 TI - [Gastric localizations of chronic lymphoid leukemia]. PMID- 4306436 TI - [2 cancers of the large gastric tuberosity]. PMID- 4306437 TI - [Digestive lymphosarcomatosis simulating benign ulcerated gastric tumors]. PMID- 4306438 TI - [Traumatic rupture of the stomach]. PMID- 4306439 TI - [Bilio-digestive fistula and cancer of the stomach]. PMID- 4306440 TI - [Gastric schwannoma]. PMID- 4306441 TI - [Niche of the 3d duodenum and pancreatic cancer]. PMID- 4306442 TI - [Glandular epithelioma of the jejunum]. PMID- 4306443 TI - [Leiomyoma of the small intestine discovered by arteriography]. PMID- 4306444 TI - [Crohn's disease of the jejunum fistulized in the sigmoid]. PMID- 4306445 TI - [Crohn's disease with duodenal and ileocecal localizations]. PMID- 4306446 TI - [Meckel's diverticulum]. PMID- 4306447 TI - [Schwannoma of the small intestine and ileo-ileal invagination]. PMID- 4306449 TI - [Dieulafoy's treacherous period of quiet and lacunar image of the cecum]. PMID- 4306448 TI - [Appendicitis with a tumoral form]. PMID- 4306450 TI - [Colic invagination of a cancer of Bauhin's valva]. PMID- 4306451 TI - [Enormous cancer of the transverse colon without evocative radiologic signs]. PMID- 4306452 TI - [Triple localization of a recto-colic cancer]. PMID- 4306453 TI - [A new case of Crohn's disease of the colon]. PMID- 4306454 TI - [Alveolar echinococcosis of the liver]. PMID- 4306455 TI - [Huge mega-bladder]. PMID- 4306456 TI - [Aberrant pancreas of the gastric antrum]. PMID- 4306457 TI - [On the study of lymphoreticular reactions in human tonsil cell suspensions]. PMID- 4306458 TI - [Contribution to the development of lung cancer: transformation of a peripheral circular focus carcinoma into a central lung cancer]. PMID- 4306459 TI - [Value of mass chest X-ray for the diagnosis of lung cancer]. PMID- 4306460 TI - [Late results in the surgical treatment of lung cancer diagnosed by mass chest X ray]. PMID- 4306461 TI - The suppression of catechol oxidase activity during the enzymic hydroxylation of p-coumaric acid by spinach leaf phenolase. PMID- 4306462 TI - Hydrolase activities in differentiating plant tissues. PMID- 4306463 TI - The periodate oxidation of bovine bone sialoprotein, and some observations on its structure. AB - 1. Bovine bone sialoprotein (mol.wt. 23000) contains N-acetylneuraminic acid and N-glycollylneuraminic acid, fucose, galactose, mannose, N-acetylgalactosamine and N-acetylglucosamine residues in the form of a very small number, perhaps one, of highly branched oligosaccharide structures linked covalently to peptide. 2. Periodate oxidation of the sialoprotein results in quantitative destruction only of the sialic acid and fucose residue consistent with the earlier findings of their positions as terminal groups. 3. Terminal sialic acid residues are attached to galactopyranose residues by 2,3-linkages, and to some N-acetylgalactosamine residues (at C-6). 4. Sequential Smith degradation indicates that N acetylgalactosamine residues may be present as points of branching (linked in C 1, C-3 and C-6) and N-acetylglucosamine residues are located in the inner part of the structure, adjacent to the carbohydrate-peptide bond(s). 5. Mannose residues appear to be linked in the 1,3-positions. PMID- 4306465 TI - Complex-formation between triphosphoinositide and experimental allergic encephalitogenic protein. PMID- 4306464 TI - The isolation and properties of experimental allergic encephalitogenic protein. AB - 1. Experimental allergic encephalitogenic (EAE) protein was isolated from ox spinal cord by a modification of the method of Martenson & LeBaron (1966). 2. The protein was examined by acrylamide-gel electrophoresis and its amino acid composition determined. 3. Sedimentation-velocity runs in the ultracentrifuge indicate a molecular weight of about 15100 at pH7.8, and calculation suggests that approx. 137 amino acid residues are present per molecule. 4. Gel-filtration and diffusion studies suggest that the protein is non-globular. 5. Optical rotatory-dispersion measurements show the protein to have no helical secondary structure even at pH values near to the isoelectric point. In the presence of triphosphoinositide, changes in the optical rotatory dispersion of the protein could be interpreted to mean that it develops a small degree of secondary structure. 6. On treatment with cyanogen bromide the experimental allergic encephalitogenic protein is split into at least two fragments, the larger of which is only about 12% smaller than the parent protein and is antigenically active, and the smaller of which is devoid of antigenic activity. PMID- 4306466 TI - Complex-formation between triphosphoinositide and experimental allergic encephalitogenic protein. AB - 1. Reactions between triphosphoinositide and the basic experimental allergic encephalitogenic (EAE) protein were examined in aqueous solution and in a biphasic solvent system (chloroform-methanol-water, 8:4:3, by vol.). 2. In the absence of salt an insoluble complex (I) is formed containing triphosphoinositide and EAE protein in proportions that represent complete neutralization of lipid and protein at the pH concerned. 3. In the presence of a low concentration (0.05m) of sodium chloride an insoluble positively charged complex (II) forms. It contains triphosphoinositide and EAE protein in a lower concentration ratio than complex I. This complex, which has a constant composition between pH7.5 and pH10, can take up additional micellar triphosphoinositide producing complex I, which can then be solubilized by excess of triphosphoinositide. 4. The complexes are dissociated by more concentrated sodium chloride solutions and low concentrations of calcium chloride, suggesting that they are largely stabilized by electrostatic bonds. The protein recovered after dissociation is immunologically active and has the same electrophoretic mobility as the original. 5. Water-insoluble ternary complexes containing triphosphoinositide, EAE protein and large amounts of phosphatidylcholine can be prepared. From these, chloroform-methanol (2:1, v/v) extracts only phosphatidylcholine. 6. An insoluble ternary complex of Ca(2+) ion, EAE protein and triphosphoinositide can be prepared by adding calcium chloride to a complex I preparation solubilized by excess of triphosphoinositide. 7. EAE protein will also form complexes with other acidic phospholipids, e.g. phosphatidic acid, phosphatidylserine and phosphatidylinositol, but not with phosphatidylcholine or phosphatidylethanolamine. The phosphatidylinositol and phosphatidylserine complexes are chloroform soluble, i.e. proteolipids. 8. The possibility that complexes between EAE protein and acidic phospholipids occur in vivo is discussed. Triphosphoinositide and EAE protein occur in ox brain myelin in approximately the same concentration ratios as they do in complex II, formed at physiological salt concentration and pH. PMID- 4306467 TI - Effect of iron deficiency on certain iron-dependent enzymes in haemopoietic tissue in bone marrow. PMID- 4306468 TI - [Research on oxidation mechanisms in Pseudomonas fluorescens. VI. Regulation of catalase activity]. PMID- 4306469 TI - [Contribution to cytomegalovirus inclusion disease in the newborn]. PMID- 4306470 TI - [Contribution to the viral etiology of acute respiratory diseases of children in nurseries]. PMID- 4306471 TI - [Examination of the secretory capacity of the stomach using Lambling's method in 41 children]. PMID- 4306472 TI - Experimental and theoretical approaches to neural processing in the central auditory pathway. PMID- 4306473 TI - Metabolic effects of feeding aspirin to rats at simulated altitude. PMID- 4306474 TI - Kidney function in the high-altitude native. PMID- 4306475 TI - Effect of cold exposure and ACTH on RNA, DNA and protein content in adrenal and liver of rats and ground squirrels. PMID- 4306476 TI - Effects of conditioning and some drugs on cold adaptation in rats. PMID- 4306477 TI - Mechanism of induction of cytochrome oxidase in yeast. I. Kinetics of induction and evidence for accumulation of cytoplasmic and mitochondrial precursors. PMID- 4306478 TI - Effect of ACTH on the metabolism of pregnenolone-7 alpha-3H and cortisol-4-14C in young and elderly men. PMID- 4306479 TI - Studies on the efficiency of adrenocortical 11 beta-hydroxylation in the human subject. PMID- 4306480 TI - Pituitary-adrenal function in arrested hydrocephalus. PMID- 4306481 TI - Human growth hormone release during sleep: electroencephalographic correlation. PMID- 4306483 TI - Embryonal carcinoma of the pineal region. PMID- 4306482 TI - 2,4-diaminopyrimidines. The cyclization of 6-phenacylthio and related derivatives to thieno[2,3-d]pyrimidines and thiazolo[3,2-c]pyrimidines. PMID- 4306484 TI - The effect of hyperbaric oxygen on mitochondrial enzymes, lipid peroxides and adenosine triphosphate-induced contraction of mitochondria in organ cultures and cell fractions of rat liver. PMID- 4306485 TI - [Cholinesterase, 5-nucleotidase, ATP-ase, lactate dehydrogenase and fructosediphosphate aldolase activity in the organs and body fluids of Vipera aspis (venom excluded)]. PMID- 4306486 TI - [Radioangiographic study of circulation in the villi and intervillous space of isolated human placental cotyledon kept viable by perfusion]. PMID- 4306487 TI - [Contribution to the study of hypophosphatasia]. PMID- 4306489 TI - [Multiple pagetoid epitheliomas appearing on an area formerly strongly irradiated by x-rays]. PMID- 4306488 TI - [Recurrent herpes of the face and vulva with very unusual, extensive, inflammed adenopathy]. PMID- 4306490 TI - Active acromegaly with anterior pituitary failure. PMID- 4306491 TI - EMPIRICISM AND MAGIC IN Aztec pharmacology. PMID- 4306492 TI - Further experiments with alcohol-treated hepatitogenic serum. PMID- 4306493 TI - [So-called mixed (or epitheliomas of altered stoma), parotid and non-parotid tumors. Remarks apropos of 117 operated cases]. PMID- 4306494 TI - Herpes simplex panuveitis. A clinical report. PMID- 4306495 TI - Chronic herpes simplex infection of the ocular adnexa. Persistence of virus in the rabbit after enucleation. PMID- 4306496 TI - Prophylaxis of herpetic keratoconjunctivitis with interferon inducers. Preliminary observations. PMID- 4306497 TI - [On the inhibitory effect of phosphate compounds on experimental vascular calcinosis]. PMID- 4306498 TI - Aldolase. II. Spectrophotometric determination using an ultraviolet procedure. PMID- 4306499 TI - Enzyme content of casts in chronic renal disease. PMID- 4306500 TI - Alteration by oral contraceptives of normal menstrual changes in plasma renin activity, concentration and substrate. PMID- 4306501 TI - Pathological lesions, including tumors, in rats after 4,4'-diaminodiphenylmethane and gamma-butyrolactone. PMID- 4306502 TI - Studies on the role of the thymus in viral tumorigenesis. I. Effect of thymectomy on induction of hyperplastic alveolar nodules and mammary tumors in BALB-cfC3H mice. PMID- 4306503 TI - Studies on the role of the thymus in viral tumorigenesis. II. Effect of thymectomy on induction of hyperplastic alveolar nodules in BALB-c mice infected with mammary tumor virus at various ages. PMID- 4306504 TI - Inhibition of the growth of cultured cells by arginase and soluble proteins from mouse skin. PMID- 4306505 TI - Infection with Entameba histolytica and the clinical syndrome of amebiasis. Incidence in a general hospital in Israel. PMID- 4306507 TI - Flavin and pyridine nucleotide oxidation-reduction changes in perfused rat liver. I. Anoxia and subcellular localization of fluorescent flavoproteins. PMID- 4306506 TI - A comparison of the effects of lipolytic and antilipolytic agents on adenosine 3',5'-monophosphate levels in adipose cells as determined by prior labeling with adenine-8-14C. PMID- 4306508 TI - Structures of the D-galactose oligosaccharides from earthworm cuticle collagen. PMID- 4306509 TI - Isolation and enzymatic properties of the mitochondrial reduced diphosphopyridine nucleotide dehydrogenase. PMID- 4306510 TI - Inhibitors and activators of the mitochondrial reduced diphosphopyridine nucleotide dehydrogenase. PMID- 4306512 TI - Enzymes of nucleic acid metabolism from wheat seedlings. I. Purification and general properties of associated deoxyribonuclease, ribonuclease, and 3' nucleotidase activities. PMID- 4306511 TI - Properties of pure acyl phosphatase from bovine brain. PMID- 4306513 TI - Interaction of a spin-labeled analogue of nicotinamide adenine dinucleotide with alcohol dehydrogenase. 3. Thermodynamic, kinetic, and structural properties of ternary complexes as determined by nuclear magnetic resonance. PMID- 4306515 TI - Association-dissociation reactions of mitochondrial isocitric dehydrogenase induced by protons and various ligands. PMID- 4306514 TI - Structure and function of transfer ribonucleic acid. 3. Some properties of a complex between valyl transfer ribonucleic acid synthetase and transfer ribonucleic acid specific for valine. PMID- 4306516 TI - Purine N-oxides. 28. The reduction of purine N-oxides by xanthine oxidase. PMID- 4306518 TI - On the production and release of chemical transmitters and related topics in cellular control. PMID- 4306517 TI - Findings of antibodies to animal influenza viruses in human sera and their significance for the study of interviral antigenic relationship. PMID- 4306519 TI - Viral enteric infections among diarrhoeal and non-diarrhoeal infants in Tehran, Iran. PMID- 4306520 TI - [Cytomegalic inclusion diseases in children, its clinical forms and intravital diagnosis]. PMID- 4306521 TI - Complementation and transformation by temperature-sensitive mutants of polyoma virus. PMID- 4306522 TI - Temperature-sensitive mutants of polyoma virus. PMID- 4306523 TI - Properties of clonal lines of murine sarcoma virus transformed Balb-3T3 cells. PMID- 4306524 TI - The N-terminal amino acid of an avian leukosis group-specific antigen from avian myeloblastosis virus. PMID- 4306525 TI - Concerning the egress of herpes simplex virus from infected cells: electron and light microscope observations. PMID- 4306526 TI - [Pediatric guidelines. 16. Advice to children with liver diseases]. PMID- 4306527 TI - A histochemical study on the distribution and localization of beta-glucuronidase activity in cerebral tumors. PMID- 4306528 TI - The influence of pituitary hormones and norepinephrine on the size of adipose cells in organ culture. PMID- 4306529 TI - [The impulse currents of low frequency and the perspectives of their use for the prevention of pain aggravation in radicular syndrome]. PMID- 4306530 TI - [Adenovirus infection in Dakar. Sero-epidemiologic survey]. PMID- 4306532 TI - E.S.R. studies of nitroxide probes in lecithin-water systems. PMID- 4306533 TI - Spontaneous activity of cat hippocampal neurons in sleep and wakefulness. PMID- 4306531 TI - [On various pharmacodynamic and biologic properties of venom of serpents of the genus Bothrops (B. jararaca, B. atrox, B. lanceolatus and B. carribeaus)]. PMID- 4306534 TI - Correlated firing of hippocampal neuron pairs in sleep and wakefulness. PMID- 4306535 TI - [Combined hormonal therapy of climacteric syndrome using tristeroid preparation "Trophobolene"]. PMID- 4306536 TI - [Mixed mesodermal malignant tumors of the generative tract]. PMID- 4306537 TI - Susceptibility to polymyxin B in penicillin G-induced Proteus mirabilis L forms and spheroplasts. AB - A polymyxin B-resistant strain of Proteus mirabilis was converted into L forms and spheroplasts in the presence of penicillin G. This treatment caused a 400 fold increase in polymyxin B susceptibility. The acquired susceptibility was in the range of the natural susceptibility reported for susceptible gram-negative bacteria ( approximately 1 mug/ml). The high susceptibility to polymyxin B was lost as soon as the spheroplasts and L forms were allowed to reconvert into the bacillary form in penicillin-free media. This behavior is strong evidence that the natural resistance of Proteus strains to polymyxins is due to the impermeability of the outer cell wall structures to these antibiotic substances. PMID- 4306538 TI - Sensitivity of Pseudomonas aeruginosa to normal serum and to polymyxin. AB - Strains of Pseudomonas aeruginosa isolated from clinical material were very variable in their sensitivity to the bactericidal action of normal serum mediated by the complement system. Fifty per cent killing end points ranged from 0.015 ml to greater than 0.4 ml. Most of the strains with relatively greater sensitivity to serum were isolated from patients with cystic fibrosis. Immunization of rabbits resulted in antisera with enhanced levels of bactericidal antibody, except with one strain which was resistant to the bactericidal action of normal serum and antiserum. When P. aeruginosa was cultivated at 41 C instead of at 37 C, it was significantly more sensitive to serum and to several antibiotics, thereby implicating fever as a host defense mechanism in Pseudomonas infections. In contrast to their heterogeneity to serum bactericidal activity, the strains were relatively homogeneous in their sensitivity to polymyxin, with no apparent association between their sensitivity to the two antimicrobial agents. PMID- 4306539 TI - Collagenolytic activity of bacteria. AB - Actively growing aerobic and anaerobic bacteria were screened by a plate assay, with reconstituted guinea pig collagen as a substrate, for their ability to produce a collagenolytic factor. Collagenolytic activity was not demonstrated among the aerobic organisms tested, with the exception of one strain of Staphylococcus aureus (only when grown under anaerobic conditions). Collagenolytic activity, however, was detected in cultures of Clostridium tetani and Bacteroides species other than B. melaninogenicus. Collagenolytic activity of these organisms could be confirmed by measuring the amount of hydroxyproline liberated from the collagen gel during growth. Although collagenase production by Pseudomonas aeruginosa has been suggested in previous reports, our results were negative. An extracellular fraction of P. aeruginosa was able to hydrolyze a synthetic hexapeptide Cbz-glycyl-l-prolyl-glycyl-glycyl-l-prolyl-l- alanine, but was without detectable effect on reconstituted collagen. PMID- 4306540 TI - Malate utilization by a group D Streptococcus: physiological properties and purification of an inducible malic enzyme. AB - Growth of Streptococcus faecalis in the presence of l-malate resulted in the induction of a "malic enzyme" [l-malate:nicotinamide adenine dinucleotide (NAD) oxidoreductase (decarboxylating), E.C. 1.1.1.39]. Synthesis of the malic enzyme did not appear to be subject to catabolite repression by intermediate products of glucose or fructose dissimilation. However, malate utilization was inhibited during growth in the presence of glucose or fructose. The purified enzyme was specific for malate as substrate and NAD as cofactor. Mn(+2) or Mg(+2) was required for optimal activity and NH(4)Cl stimulated the reaction rate. Several lines of indirect evidence suggested that the streptococcal malic enzyme was involved primarily with energy production and not biosynthesis. PMID- 4306541 TI - Effect of copper deficiency on chick bone collagen and selected bone enzymes. PMID- 4306542 TI - Potassium activated phosphatase from human red blood cells. The mechanism of potassium activation. AB - 1. The kinetic behaviour of the K-activated phosphatase in human red blood cell membranes has been investigated. The concentration of Mg required to give optimal activation is independent of substrate and K concentration, suggesting that Mg combines with the enzyme at a site that is independent of and non-interacting with the substrate and K sites.2. The effects of K are competitively antagonized by Na. Ouabain in suitable concentrations selectively abolishes the activating effect of K.3. Comparison between the hydrolysis of acetylphosphate by intact red cells and by fragmented ghosts suggests that the active site for the substrate is only accessible at the internal surface of the cell membrane.4. The plot of the total rate of p-nitrophenylphosphate hydrolysis versus substrate concentration can be fitted at any K concentration by a rectangular hyperbola. The effect on the total rate of increasing K concentration is exerted mainly on the apparent affinity for the substrate, which increases about 5 times as K goes from 0 to 55 mM. There is also a much smaller increase in the maximum velocity (about 1.3 times) for the same range of K concentrations.5. If the difference between the activity in the absence and in the presence of K is plotted as a function of substrate concentration, the curves obtained are no longer hyperbolic but pass through a maximum and then tend to a lower value.6. This kinetic behaviour can be explained much more easily by assuming that a single enzyme is responsible for the hydrolysis of the substrate in the presence and in the absence of K. A simple kinetic model based on this assumption was developed and when experimentally determined constants were fitted into the equations that predict its behaviour a reasonably good agreement between theory and experiment was obtained.7. In the ;single enzyme' model inhibitors that selectively abolish the K-dependent activity would act by blocking the combination of the enzyme with K. A simple treatment based on this idea was developed for the case of Na and its predictions were fulfilled by the experimental results.8. In the ;single enzyme' model the K coupled hydrolysis is always larger than the difference between the rates in the presence and in the absence of K, and when K concentration is non-limiting the K coupled rate is equal to the total rate. PMID- 4306543 TI - Correlation between transmission and structure in avian ciliary ganglion synapses. AB - 1. Extracellular responses from post-ganglionic axons of pigeon and chick isolated ciliary ganglia were elicited by stimulation of the presynaptic nerve. Intracellular recordings were also obtained from newly hatched pigeon and chick ganglion cells. The fine structure of ganglia from pigeons of various ages was examined with the electron microscope.2. In ganglia from chick embryos and pigeons up to 10 days old, the extracellular response was unimodal with a long latency and could be blocked by the addition of D-tubocurarine (D-TC) or hexamethonium to the bathing solution. A bimodal extracellular response appeared in pigeons about 10 days after hatching. Only the second peak of the response could be blocked by D-TC or hexamethonium. The response recorded from 22 to 26 day-old pigeons was similar to that seen in the adult.3. The intracellular recordings from ganglion cells of 2-week-old pigeons exhibit two post-synaptic potentials elicited by presynaptic stimulation. The first post-synaptic potential appears to be due to current flow through the ganglion cell during the presynaptic action potential. The second is chemically mediated. In pigeons from 1 to 6 days old, only the second post-synaptic potential is observed.4. The presynaptic terminals in the 4-day-old birds were in the form of calyces. In pigeons 7 days old or older, boutons appeared. The boutons were presumably formed as a result of cleavage of calyciform nerve terminals. Myelin was seen first in the 7-day-old pigeon, was well developed in the 16-day-old bird, and persisted in the adults.5. In adult ganglia, the first component of the extracellular response decreased and was finally abolished after 10-12 hr of superfusion with Tyrode solution. The second component of the response increased concomitantly. The only anatomical change noted in the ganglia after soaking was the disruption and separation of the myelin lamellae from each other and from around the ganglion and presynaptic terminals.6. It is concluded that the myelin is necessary for electrical transmission in the pigeon ciliary ganglion. PMID- 4306545 TI - [Skin window method in clinical studies of malignant diseases]. PMID- 4306544 TI - Changes in carotid sinus baroreceptor activity induced by angiotensin. PMID- 4306547 TI - [Roentgenodiagnosis of tumors and tumor-like formations of the mammary glands]. PMID- 4306546 TI - [Detection of exophthalmus producing factor (EPF) in hyperthyroidism and its sensitization by carticotropin]. PMID- 4306548 TI - [Malignant paraganglioma of the stomach (one case)]. PMID- 4306549 TI - [Roentgenomorphologic parallels in nodular forms of cancer of the mammary glands]. PMID- 4306550 TI - [On the localization of Ag and Lp by means of density gradient ultracentrifugation]. PMID- 4306551 TI - Effects of some cancer-chemotherapeutic agents, especially cyclophosphamide, on an SV40 sarcoma in rat. PMID- 4306553 TI - [The effect of hypophysectomy on the proliferative activity of normal and malignant tissue]. PMID- 4306552 TI - Comparative effects of tumor extracts on lymphocyte transformation in peripheral blood cultures of healthy persons and patients with breast cancer. PMID- 4306554 TI - [A study of the activity of L-asparaginase in Escherichia coli of various types]. PMID- 4306555 TI - [The diffusion factor of C1. perfringens types A, B, C, D, E and F]. PMID- 4306556 TI - [A study of diphtheria toxin and anatoxin by the method of electron paramagnetic resonance]. PMID- 4306557 TI - [Glial function in the view of recent histochemical findings]. PMID- 4306558 TI - Calcifying epithelial odontogenic tumour. PMID- 4306559 TI - Corticotrophin and its synthetic analogues. PMID- 4306560 TI - [Attempt at active specific immunotherapy in liver carcinoma]. PMID- 4306561 TI - [Serum inhibitors of streptolysin O in primary liver cancer]. PMID- 4306562 TI - [Inclusion bodies in 2 primary liver cancers in man]. PMID- 4306563 TI - [Comparative study of primary liver carcinoma in Europe and black Africa]. PMID- 4306564 TI - [Neurologic forms of primary liver cancer (clinical and electroencephalographic study)]. PMID- 4306565 TI - [Medullary compression due to clinically inapparent liver cancer metastasis (apropos of 10 cases)]. PMID- 4306566 TI - [Our experience with surgical treatment of primary liver cancer]. PMID- 4306568 TI - [Primary liver cancer in children (apropos of 2 Senegalese cases)]. PMID- 4306567 TI - [Various surgical exereses of hepatocarcinoma in African Negroes]. PMID- 4306569 TI - The two kinds of doctor. PMID- 4306570 TI - [Emergency urology in infants and children]. PMID- 4306571 TI - [On mucinous prostate carcinomas]. PMID- 4306573 TI - [Plain radiology findings in vascular abnormalities of the skin and subcutaneous tissue]. PMID- 4306572 TI - Localization of the hypotenisve effect of 2-(2-6-dichlorophenylamino)-2 imidazoline hydrochloride (St 155, Catapresan). PMID- 4306575 TI - An attempt to type some of the untyped enteroviruses with antisera prepared against two of these untyped viruses. PMID- 4306574 TI - [A new immersion liquid for detecting free crystalline silicon dioxide under the microscope]. PMID- 4306576 TI - Neonatal smiling and rapid eye movement states. PMID- 4306578 TI - Acute hepatitis due to Herpes simplex virus in an adult. AB - A case is described of herpetic hepatitis in a pregnant woman with primary herpetic stomatitis. Intranuclear inclusion bodies and virus particles were found in hepatocytes, and herpes virus was isolated from a liver biopsy and from oral swabs but not from blood. From rising titres of neutralizing and complement fixing antibody it is concluded that the oral infection was a primary one. Factors predisposing to the hepatitis are discussed. PMID- 4306577 TI - Electron microscopic observations on the virus particles in Herpes simplex encephalitis. AB - Cerebral cortex from eight fatal cases of Herpes simplex encephalitis has been studied by electron microscopy. The diagnosis had been based on clinical findings, necropsy evidence of bitemporal necrosis, and histological confirmation of intranuclear inclusions with a lymphocytic inflammatory response, even though virus cultures were unsuccessful. Virus particles were seen predominantly in nuclei in six of these cases, utilizing tissue which had been preserved in formalin for up to four years or had been embedded in paraffin. Although demonstration of these particles is only indicative of the herpes group and not specifically of Herpes simplex, electron microscopy of either biopsy or postmortem material may be a useful adjunct in making the diagnosis and can be accomplished before virological studies have been completed. PMID- 4306579 TI - [Carcinoid tumor of the right main bronchus treated by bronchotomy and broncho anastomosis. Correction of respiratory and circulatory disorders]. PMID- 4306580 TI - Labeled dopamine concentration in human adrenal medulla and in neuroblastoma. PMID- 4306581 TI - [Therapeutic practice. XV. Therapy of the nephrotic syndrome]. PMID- 4306582 TI - [Angiotensin]. PMID- 4306583 TI - Sodium metabolism. PMID- 4306584 TI - [The effect of alloxan diabetes and hunger on the level of acetylation coenzyme and nicotineamide-adenine dinucleotide in the liver in rats of various ages]. PMID- 4306585 TI - [Thecoma and adenocarcinoma of the endometrium. (Anatomo-clinical observations on a case)]. PMID- 4306586 TI - Acute peripheral neuropathy. PMID- 4306587 TI - [Contribution on the clinical aspects and therapy of testicular tumors]. PMID- 4306588 TI - Purification and characterization of bluetongue virus. PMID- 4306589 TI - Morphology of bluetongue virus. PMID- 4306590 TI - Lipids of plasma membranes of monkey and hamster kidney cells and of parainfluenza virions grown in these cells. PMID- 4306591 TI - Multiple antigenic components of the group-specific antigen of the avian leukosis sarcoma viruses. PMID- 4306592 TI - The formation of variants with a reversion of properties of transformed cells. II. In vitro formation of variants from polyoma-transformed cells. PMID- 4306593 TI - The structure of the mammary tumor virus. PMID- 4306594 TI - [On the modification of serum lipids in healthy postmenopausal women by conjugated estrogens. II]. PMID- 4306595 TI - Binding of NAD+ to rabbit-muscle glyceraldehydephosphate dehydrogenase as studied by optical rotatory dispersion and circular dichroism. PMID- 4306596 TI - Nucleotidase activities in the soluble fraction of rat liver homogenate. Partial purification and properties of a 5'-nucleotidase with pH optimum 6.3. PMID- 4306597 TI - Relation of cerebrospinal fluid circulation to the ACTH-suppressing effects of corticosteroid implants in the rat brain. PMID- 4306598 TI - Responsiveness to lipolytic hormones, and inactivation of adrenocorticotropin, by adipose tissue slices and free fat cells from different mammalian species. PMID- 4306599 TI - Lipolytic activity of synthetic porcine secretin. PMID- 4306600 TI - Immunoassayable insulin content of subcellular fractions of rat islets. PMID- 4306601 TI - Stimulation of thyroid hormone secretion by dibutyryl cyclic-AMP. PMID- 4306602 TI - Adrenal cells in tissue culture. IV. Use of an inhibitor of steroid synthesis for the study of ACTH action. PMID- 4306603 TI - Effect of corticotropin-releasing factor, dexamethasone and actinomycin D on the release of ACTH from rat pituitaries in vivo and in vitro. PMID- 4306604 TI - Acute effect of overtransfusion of plasma renin activity in the rat. PMID- 4306606 TI - Dexamethasone suppression of ACTH release: effect of the interval between steroid administration and the application of stimuli known to release ACTH. PMID- 4306605 TI - Adrenal sterol metabolism in the hamster following ACTH and cortisol administration. PMID- 4306607 TI - Suppression of the hypothalami- c-pituitary-adrenal axis in the newborn dog. PMID- 4306608 TI - Intra- oral removal of large juvenile angiofibroma. PMID- 4306609 TI - [Synaptic transmission of proprioceptive and cutaneous discharges through the Burdach nucleus]. PMID- 4306610 TI - [Synaptic potentials of the neurons of the main sensory trigeminal nucleus]. PMID- 4306611 TI - [Primary hyperparathyroidism]. PMID- 4306612 TI - "Retrograde" metastasis of primary carcinoma of the liver to the stomach. PMID- 4306613 TI - Differential responses to fasting and subsequent feeding by microsomal systems of rat liver: 6- and 9-desaturation of fatty acids. AB - Hepatic microsomal preparations from nonfasted, fasted, and fasted-fed rats were employed, together with cofactors, in studies of 9-desaturation of stearate-1 (14)C and 6-desaturation of linolenate-1-(14)C. Prior fasting sharply reduced 9 desaturation but did not affect 6-desaturation; feeding restored 9-desaturation. Position of desaturation was determined by permanganate-periodate oxidation and separation of the dicarboxylic acids. Feeding after fasting stimulated both desaturase systems but either dl-ethionine or actinomycin D prevented this. Dietary carbohydrate or saturated fat increased 9-desaturation and dietary protein increased 6-desaturation. Insulin treatment of nonfasted rats increased 9 desaturation but not 6-desaturation. High dietary unsaturated fat (20% safflower oil) stimulated 6-desaturation but inhibited the 9-desaturation response to feeding. The results indicate that the two desaturases are distinct and are inducible in response to different substances. PMID- 4306614 TI - Lipid abnormalities in foam cell reticulosis of mice, an analogue of human sphingomyelin lipidosis. AB - The lipid changes in the inheritable foam cell reticulosis of mice discovered by Lyons, Hulse, and Rowe have been reexamined. The major abnormality in thymuses from homozygous-abnormal animals has been identified as an increase in the concentration (per milligram of protein) of sphingomyelin and cholesterol. This increase is associated with normal sphingomyelin-cleaving activity. The lipid compositions of the liver and spleen in the homozygous-abnormal animal and of the thymus in the heterozygous-abnormal mouse are normal. The disorder appears to be chemically analogous to those forms of human sphingomyelin lipidosis (Niemann Pick disease) that are not accompanied by a decrease in tissue sphingomyelinase. PMID- 4306615 TI - Preparative thin-layer and column chromatography of prostaglandins. PMID- 4306616 TI - Evidence for separate monoglyceride hydrolase and triglyceride lipase in post heparin human plasma. AB - Post-heparin plasma contains an enzyme or enzymes with both triglyceride lipase (TGL) and monoglyceride hydrolase (MGH) activities. A simple and reproducible radioactive assay for measurement of MGH activity was developed and used, with a previously reported assay for TGL, to study lipolysis in plasma. After the injection of heparin, enzymatic activity against both tri- and monoglycerides appeared and disappeared from plasma at approximately the same rates. However, in contrast to TGL activity, MGH activity was: (a) much greater, (b) considerably less heat-sensitive, (c) unaffected by three inhibitors (NaCl, protamine, and pyrophosphate), (d) not influenced by radical changes in fat and carbohydrate content of the diet, and (e) normal in familial Type I hyperlipoproteinemia. The dichotomy between MGH and TGL activities in patients with genetic deficiency of TGL constitutes strong evidence that these are two different enzymes. The findings further indicate that when post-heparin lipolytic activity is measured for the purpose of detecting TGL deficiency, it may be necessary to perform the assay with a substrate free from partial glycerides. PMID- 4306620 TI - Regeneration of the liver after hepatectomy. PMID- 4306619 TI - Characterization of two BALB-c infant thymus cell lines infected with lympholeukemogenic virus. PMID- 4306618 TI - Detection of antibodies against the mammary tumor virus with the antiglobulin consumption test. PMID- 4306617 TI - Hemorrhagic lesions produced by Claude's chicken tumor-10 virus. PMID- 4306621 TI - [Enzymology of milk]. PMID- 4306622 TI - Paget's disease of the breast: the influence of the presence or absence of an underlying palpable tumor on the prognosis and on the choice of treatment. PMID- 4306623 TI - [Noradrenaline-dependent vasoconstrictor action of angiotensin in the isolated aortic strip preparation of the rat]. PMID- 4306624 TI - [Effect of angiotensin II on tubular sodium and water reabsorption in the rat]. PMID- 4306625 TI - [Isolation and enzymatic characterization of a brushborder fraction of rat kidney]. PMID- 4306626 TI - [Epidemiological and bacteriological study of food poisoning epidemics in the district of Paris in 1966-1967]. PMID- 4306627 TI - Formation of extracellular adenosine triphosphate by tumour cells. PMID- 4306628 TI - Blockade of the phosphorylase alpha-activating effects of catecholamines and adenosine 3',5'-monophosphate (cyclic AMP) in high K+ or choline buffer media. PMID- 4306629 TI - The effect of nerve stimulation on the uptake of noradrenaline into the adrenergic nerve terminals. PMID- 4306631 TI - Inhibitory processes in gustation. PMID- 4306630 TI - The effect of nerve stimulation on catecholamines taken up in adrenergic nerves after reserpine pretreatment. PMID- 4306632 TI - Relation of afferent nerve excitability to impulse generation in the frog spindle. PMID- 4306633 TI - The amoebicidal activity and toxicity of natural emetine, (plus or minus)-2 dehydroemetine and (--)-2-dehydroemetine. PMID- 4306635 TI - [Determination of renin activity in normal and hypertensive patients]. PMID- 4306634 TI - Total lipodystrophy. PMID- 4306636 TI - [Antimicrobial effect of potential isothiocyanate-formers. 5]. PMID- 4306637 TI - Quantum yield for the photoproduced electron paramagnetic resonance signal in chromatophores from Rhodospirillum rubrum. PMID- 4306638 TI - The 5'-linked termini of plant ribosomal ribonucleic acids. PMID- 4306639 TI - The state of iron in hemerythrin. A Mossbauer study. PMID- 4306640 TI - The synthesis of 5-fluorouridine 5'-phosphate by a pyrimidine phosphoribosyltransferase of mammalian origin. I. Some properties of the enzyme from P1534J mouse leukemic cells. PMID- 4306641 TI - Pyridine coenzymes. VII. Catalysis of the hydration of the reduced form by iodoaromatic compounds. PMID- 4306642 TI - The purification and properties of rat muscle glycogen phosphorylase. PMID- 4306644 TI - [A study of the effect of bacterial endotoxins on oxidative phosphorylation in the liver]. PMID- 4306643 TI - Conformational changes in the molecular control of muscle contraction. PMID- 4306645 TI - Phosphodiesterase in psoriasis. PMID- 4306646 TI - [Action of pyronine on the multiplication of encephalomyocarditis virus (EMC) in mice]. PMID- 4306647 TI - [Synthesis of "repressor" to SV40 virus during productive and abortive infection]. PMID- 4306648 TI - [Kinetics of cell membrane antigen in the polyoma virus--hamster system]. PMID- 4306649 TI - Hemodynamic changes during sleep in hypertensive patients. PMID- 4306650 TI - [Histochemical studies on certain enzymes in dental pulp in the course of parodontopathy]. PMID- 4306651 TI - [Behavior of glycogen and PAS-positive substances in human placenta in various stages of its development]. PMID- 4306652 TI - Age at menarche: a new method of prediction and retrospective assessment based on hand x-rays. PMID- 4306653 TI - Decreased rate of synthesis of immunoglobulin (IgG) in rats infected with moloney leukemia virus. PMID- 4306654 TI - [Histopathological and histochemical changes in the liver of dogs during extracorporeal perfusion]. PMID- 4306655 TI - [Gelatinous carcinoma of the appendix]. PMID- 4306656 TI - [Genital malignancies from 1956-1965 in the district of Potsdam]. PMID- 4306657 TI - [Family planning following abortion for decrease of peripartal mortality]. PMID- 4306658 TI - [Methods and results of detection of bronchial carcinoma]. PMID- 4306659 TI - [Treatment of sympathoma in children]. PMID- 4306661 TI - An analysis of the polyoma virus DNA-RNA hybridization reaction in vitro. PMID- 4306660 TI - ATP level and control of glycolysis in Novikoff ascites-hepatoma cells. PMID- 4306662 TI - 20 Beta-hydroxysteroid:NAD oxidoreductase activity towards 3 beta-hydroxypregn-5 en-20-one sulphate and related free steroids. PMID- 4306664 TI - Interactions of glucagon and insulin on the metabolism of perfused livers from fasted rats. PMID- 4306663 TI - Visualisation in the electron microscope and size of RNA from animal cells. PMID- 4306665 TI - [Evidence for the mechanism of action of sodium ethacrynate on rat liver mitochondria]. PMID- 4306666 TI - Reaction of amino acid-tRNA synthetases with 2'-deoxyadenosine triphosphate. PMID- 4306669 TI - [On summation effects in the reflex swallowing center]. PMID- 4306670 TI - [Incoordination of physiological functions as an index of fatigue]. PMID- 4306671 TI - Adenyl cyclase in cell-free extracts of Escherichia coli. PMID- 4306672 TI - Release of norepinephrine from hypothalamus and amygdala by rewarding medial forebrain bundle stimulation and amphetamine. PMID- 4306673 TI - Discussion on scope and application of current audiometric tests. PMID- 4306675 TI - Structural and functional abnormalities in mitochondria isolated from ischemic dog myocardium. PMID- 4306674 TI - Biochemistry of cerebral tumours: sodium, potassium, calcium, phosphorus, magnesium, copper and sulphur contents of astrocytomata, medulloblastomata and glioblastomata multiforme. PMID- 4306676 TI - Changes in phospholipid composition of human aorta with age. PMID- 4306678 TI - Phospholipid composition of human, bovine and frog myelin isolated on a large scale from brain and spinal cord. PMID- 4306677 TI - Isolation of highly purified human and bovine brain endothelial cells and nuclei and their phospholipid composition. PMID- 4306679 TI - Variations among vertebrates of lung phospholipid case composition. PMID- 4306680 TI - [Gentamicin (Refobacin) in the bactericidal cure treatment]. PMID- 4306681 TI - [A method for studing motor reactions of ascarids]. PMID- 4306682 TI - [Matisma--the evil eye. Diagnosis and therapy on crete]. PMID- 4306683 TI - [Cytomegalic inclusion disease in adults]. PMID- 4306684 TI - [Secondary hyperaldosteronisms]. PMID- 4306685 TI - Motor nerve conduction velocity and the electromyograph in pellagra. PMID- 4306686 TI - [The prognostic significance of cancer cells detected on the margins of the resected portion of the stomach]. PMID- 4306687 TI - [Complications of lymphography with iodolipol]. PMID- 4306688 TI - [The surgical treatment and prevention of intestinal obstruction due to adhesions with the aid of corticosteroids and anticoagulants]. PMID- 4306689 TI - [Tropical medicine problems and experiences in the DDR demonstrated by Rostock medical records]. PMID- 4306690 TI - [Enzyme-histochemical investigation of the infundibulum and neural lobe in the normal and bilaterally adrenalectomized rat]. PMID- 4306691 TI - [Isolation of serologically active components from Bord. pertussis and Bord. parapertussis by the chloroform-salt extraction method]. PMID- 4306692 TI - [The effect on tissue cultures of the toxins of Cl. perfringens types B, C, D, F]. PMID- 4306693 TI - Congenital fistula of the lacrimal sac. PMID- 4306695 TI - Area of pons necessary for traumatic stress-induced ACTH release under pentobarbital anesthesia. PMID- 4306694 TI - Central nervous system lesions that block release of ACTH caused by traumatic stress. PMID- 4306696 TI - Implications of redistribution equilibria in reactions of biological importance. PMID- 4306697 TI - [Interaction of ristomycin with heparin]. PMID- 4306699 TI - [Effect of polymyxin M on the functional status of kidneys in rabbits]. PMID- 4306698 TI - [Comparative study of effects of vancomycin and ristomycin on some biochemical processes of Staphylococcus aureus 209 P]. PMID- 4306700 TI - Effect of ascorbic acid on pulmonary silicosis of guinea pigs. PMID- 4306701 TI - Ultrastructural characteristics of adenoid cystic carcinoma of salivary glands. PMID- 4306703 TI - Aneurysm of the internal carotid artery presenting in the middle ear. PMID- 4306702 TI - The resident's page. PMID- 4306704 TI - Nasopharyngeal angiofibroma. PMID- 4306705 TI - [Incidence of cardiogenic shock in patients with acute myocardial infarct. A few remarks on mortality and therapeutic possibilities]. PMID- 4306706 TI - Determination of the molecular weight of proteins, esterases, and basic phospho monoesterases in the hemolymph of Galleria mellonella L. prepupa and pupa using a thin-layer chromatography. PMID- 4306707 TI - Simian virus 40 infection of uninoculatedAfrican green monkeys (Cercopithecus aethiops) revealed by repeated cell passages. PMID- 4306708 TI - Allergic encephalomyelitis: inhibition of cellular passive transfer by exogenous and endogenous steroids. PMID- 4306709 TI - Antagonism of polymyxin B and kanamycin sulfate by Liquoid (sodium polyanetholsulfonate) in vitro. PMID- 4306711 TI - [On inhibitory responses of neuronal complexes]. PMID- 4306710 TI - [Infulence of inhibition of proprioceptive impulses on functional development of the central nervous system in chick embryos]. PMID- 4306713 TI - Immunological relationship between herpes simplex and varicella-zoster viruses demonstrated by complement-fixation, neutralization and fluorescent antibody tests. PMID- 4306712 TI - Surface structure of foot-and-mouth disease virus. PMID- 4306714 TI - Alkaline degradation of polyoma virus. PMID- 4306715 TI - The relation of the DNA polymerase to an early temperature-sensitive event in the replication of variola virus. PMID- 4306716 TI - A possible subunit structure of Rous sarcoma virus RNA. PMID- 4306717 TI - The immunological specificity of thymidine kinases in cells infected by viruses of the herpes group. PMID- 4306719 TI - Feline herpesvirus infection in fused cultures of naturally resistant human cells. AB - Feline herpesvirus (FHV) attaches to, but does not penetrate, naturally resistant human embryonic lung cells. When the cells with attached virus are subsequently fused with inactivated Sendai virus, FHV causes characteristic cytopathic effects, but no infectious virus can be recovered from the infected cells. PMID- 4306718 TI - Replication of poliovirus in phytohemagglutinin-stimulated human lymphocytes. AB - Poliovirus replication has been studied in human lymphocytes during the course of blastogenesis under phytohemagglutinin (PHA) stimulation. Enhancement of virus replication in PHA-stimulated leukocyte cultures was due to an increase in number of virus-producing cells. Virus yield was approximately 10 plaque-forming units (PFU) per producing cell, both in stimulated and in nonstimulated cultures. Adsorption and penetration studies showed that freshly drawn lymphocytes (unlike other leukocytes) were resistant to virus infection, but they became susceptible to the virus during PHA stimulation. Also, the eclipse of the virus after penetration was enhanced during blastogenesis of the lymphocytes. Our findings suggested that the monocytes in the leukocyte cultures were infected initially. In PHA-stimulated cultures, the virus then spread to lymphocytes which became susceptible to virus infection during blastogenesis. Polymorphonuclear cells died within 24 to 48 hr after initiation of the cultures and apparently could not support poliovirus replication. PMID- 4306722 TI - Potentiation by an antagonist. PMID- 4306721 TI - Heterokaryon formation of simian virus 40-transformed cells in the presence of ultraviolet-irradiated Sendai virus. AB - Most simian virus 40-transformed mouse kidney lines form heterokaryons with CV-1 cells in the presence of ultraviolet-irradiated Sendai. However, two nonyielder lines, mKS-U2 and mKS-U20, fuse poorly. PMID- 4306720 TI - Substiuted sialic acid prosthetic groups as determinants of viral hemagglutination. AB - Inhibitors of hemagglutination by type A2 influenza virus and a recently isolated strain of type B influenza virus were separated by sucrose density gradient centrifugation and agarose gel filtration from horse serum. Using selected reagents, it was demonstrated that the active substituent on the horse serum inhibitor of A2 influenza virus was 4-O-acetyl-N-acetylneuraminic acid; however, the active substituent on the inhibitor of the influenza B virus was shown to be N-acetylneuraminic acid (NANA). Sodium metaperiodate treatment of a component of horse serum resulted in a 10 to 15-fold enhancement of inhibitory activity against the type B virus, whereas the A2 inhibitor was completely destroyed. Since this enhancement did not occur with influenza B viruses isolated prior to 1965, it was considered that this sensitivity to an oxidized NANA glycoside may have been a reflection of an antigenic change which occurred at that time. The use of different virus strains and selected chemical reagents to define the important sialic acid prosthetic groups active in inhibition was described. PMID- 4306723 TI - Serum immunoglobulin levels in postmature infants. PMID- 4306724 TI - [Peripheral rheographic changes following hypertensin infusion]. PMID- 4306725 TI - [Clinical-statistical contribution on salivary gland tumors treated at the department of dentistry and maxillofacial plastic surgery of the united municipal hospitals of Venice]. PMID- 4306726 TI - [Ectopic endocrine syndromes]. PMID- 4306727 TI - [The relationship between sex chromatin content and clinical course in cancer of the mammary glands]. PMID- 4306728 TI - [Comparative biochemical study of the activity of phosphodiesterases from the normal rat liver and Seidel's ascitic hepatoma]. PMID- 4306729 TI - [On the resistance of chick embryo cultures to Rous virus]. PMID- 4306730 TI - [Cancer of the second mammary gland]. PMID- 4306731 TI - [Contrast medium embolism following lymphography]. PMID- 4306732 TI - [An analysis of electroencephalogram changes based on the fields of average velocity change of the biopotentials in tumors of the cerebellum]. PMID- 4306733 TI - [Various features of extrapyramidal pathology in tumors of the brain in children (clinico-morphologic study)]. PMID- 4306734 TI - [Tumors of the hypophysis in Itsenko-Cushing disease]. PMID- 4306735 TI - Viral-induced enzymes and the problem of viral oncogenesis. PMID- 4306736 TI - The role of cyclic AMP in hormone actions. PMID- 4306737 TI - [Determination of plasma and urinary cortisol by competition]. PMID- 4306738 TI - Granular cell myoblastoma of larynx. Two case reports. PMID- 4306739 TI - Salivary gland neoplasms in childhood. PMID- 4306741 TI - Effects of sodium deficiency, potassium deficiency and uremia upon the steroidogenic response of rat adrenal tissue to serotonin, potassium ions and adrenocorticotropin. PMID- 4306740 TI - The adrenal gland and lactogenesis. PMID- 4306742 TI - Effects of morphine intoxication on brain catecholamine neurons. PMID- 4306743 TI - The ultrastructure of brown adipose tissue in perinatal rats. PMID- 4306745 TI - [Role of the splanchnic nerves in the transmission of impulses from the hypothalamus on absorption in the small intestine]. PMID- 4306744 TI - [Functional relations of the motor and intermediate neurons of the hypoglossal nerve nucleus in the cat]. PMID- 4306746 TI - Influence of respiration, stroke volume, and heart rate on pulmonary capillary pulsatility. PMID- 4306748 TI - Clinical and laboratory differentiation of recurrent intraoral herpes simplex virus infections following fever. PMID- 4306747 TI - Ferrous-activated nicotinamide adenine dinucleotide-linked dehydrogenase from a mutant of Escherichia coli capable of growth on 1, 2-propanediol. AB - A nicotinamide adenine dinucleotide-linked dehydrogenase has been partially purified from a mutant of Escherichia coli K-12 able to grow on l-1,2-propanediol as carbon and energy source. This enzyme catalyzes the dehydrogenation at carbon 1 of l-1,2-propanediol, glycerol, 1,3-propanediol, ethylene glycol, and ethyl alcohol. The purified protein requires added ferrous or managanous ions. The V(max) and the apparent K(m) for a given substrate vary with the particular metal used. PMID- 4306749 TI - Adrenal corticosteroids in submaxillary fluid. PMID- 4306751 TI - The role of propionic acid as a precursor of methylmalonic acid in normal and vitamin B12-deficient man. PMID- 4306750 TI - Direct fluorescence quantitation on thin-layer chromatograms. PMID- 4306753 TI - Tumor development and induction of resistance by Rous sarcoma virus in Japanese quail. PMID- 4306752 TI - Alpha toxoid of Clostridium perfringens. I. Purification and toxoiding of alpha toxin of C. perfringens. PMID- 4306754 TI - Purification of beta-toxin of Clostridium perfringens type C. PMID- 4306755 TI - Colitis--its etiology, diagnosis and treatment. PMID- 4306756 TI - [Endocrinology]. PMID- 4306757 TI - Virus-associated gain and loss of proliferative and neoplastic properties of normal and virus-transformed diploid cell lines. PMID- 4306758 TI - Inactivation of Rous Sarcoma Virus preparations detected by density gradient centrifugation. PMID- 4306759 TI - Immunological studies of choriocarcinoma. IV. The antigenicity of trophoblast. PMID- 4306760 TI - Alternate-day prednisone therapy. Evaluation of delayed hypersensitivity responses, control of disease and steroid side effects. PMID- 4306761 TI - [Biochemical and histochemical study of phosphatase activity in the adrenal glands of the rabbit]. PMID- 4306762 TI - Clinical pathologic correlations of copper. PMID- 4306763 TI - Family treatment of folie a deux. PMID- 4306764 TI - Psychiatric aftercare in a general hospital: some basic principles and their implications for community psychiatry. PMID- 4306765 TI - Generation of adrenergic and cholinergic potentials in sympathetic ganglion cells. AB - Norepinephrine elicited a hyperpolarizing response, and acetylcholine (during nicotinic blockade) elicited a depolarizing one. Both responses showed no increase in membrane conductance. The norepinephrine response was suppressed by initial depolarization; the acetylcholine response (frog cells); by hyperpolarization. These neurotransmitters apparently can activate electrogenic mechanisms which do not involve movement of ions down their electrochemical gradients. PMID- 4306766 TI - Amebiasis in Peace Corps volunteers. Clinical profile of amebiasis in American volunteers in India. PMID- 4306768 TI - Effect of botulinum toxin on speed of skeletal muscle contraction. PMID- 4306769 TI - A simple method for the detection of low concentration of viruses in large volumes of water by the membrane filter technique. PMID- 4306770 TI - Sympathetic ganglionic transmission and the cardiovascular changes of the defense reaction in the cat. PMID- 4306771 TI - Hemodynamic patterns during desynchronized sleep in intact cats and in cats with sinoaortic deafferentation. PMID- 4306767 TI - Clinical application of a simple, specific bioassay technique for measuring renin activity. PMID- 4306772 TI - Phosphatidate phosphohydrolase in frog intestinal tissue. PMID- 4306774 TI - The evolution of endopeptidases--V. Common and different traits of bovine and crayfish trypsin. PMID- 4306773 TI - Lipid metabolism in helminth parasites--VI. Synthesis of 2-cis,6-trans farnesol by Hymenolepis diminuta (Cestoda). PMID- 4306775 TI - [Effect of supra-optimal temperature on nucleolar ribonucleoproteins and RNA. 1. Ultrastructural study]. PMID- 4306776 TI - [Effect of supra-optimal temperature on nucleolar ribonucleoproteins and RNA. II. Biochemical study]. PMID- 4306777 TI - Regulation of melanin synthesis in mammalian cells, as studied by somatic hybridization. 3. A method of increasing the frequency of cell fusion. PMID- 4306778 TI - Composition and metabolism of phospholipids in cataract. PMID- 4306779 TI - [Studies on plasma 17-hydroxycorticosteroid levels in normal pregnant women and newborn infants]. PMID- 4306780 TI - Biochemical and pathological changes in rats fed brominated cottonseed oil for 80 days. PMID- 4306781 TI - Alcohol still much in demand. PMID- 4306782 TI - Antibody in polyacrylamide gel, a solid phase reagent for radioimmunoassay. PMID- 4306783 TI - The murine runting syndrome and neoplasia. PMID- 4306784 TI - The antibody activities of 19S and 7S fractions from rabbit antisera to Bordetella pertussis. PMID- 4306785 TI - Passive cutaneous anaphylaxis in the rat, induced with two homologous reagin-like antibodies and its specific inhibition with disodium cromoglycate. PMID- 4306786 TI - Mitotic and nonmitotic multiple-layered perfusion cultures. AB - Cell types in addition to those previously described (Kruse et al. 1963. J. Nat. Cancer Inst. 31:109; Kruse and Miedema. 1965. J. Cell Biol. 27:273) were found to form multiple-layered cultures by perfusion-culture technique. Dense populations containing 43 x 10(6) embryonic rat muscle (NF-ER) cells, 23 x 10(6) diploid human tonsillar (NF-JAM) cells, 77 x 10(6) human pleural effusion isolate (RPMI 2650) cells, 35 x 10(6) embryonic diploid human lung (Flow 2000) cells, 21 x 10(6) bovine lung (FB4BM) cells, 108 x 10(6) bat lung (Tb1Lu) cells, and 81 x 10(6) SV-40 virus-transformed embryonic diploid human lung (WI-38VA13A) cells were obtained in 6-14 days from dilute inocula in T-60 or T-75 flasks; these were equivalent to about 4, 3, 3, 4, 2, 4, and eight monolayers, respectively. Perfusion of an NF-ER culture for 6 wk with medium plus 10% whole calf serum yielded a cell density equivalent to 12 monolayers (140 x 10(6) cells per T-75 flask). This culture exhibited random labeling of nuclei from bottom to top after pulsing for 90 min with thymidine-(3)H. Medium plus 0.1% serum maintained NF-JAM cultures at constant viable cell numbers with virtual absence of thymidine-(3)H labeling. Similar results were obtained with WI-38 cultures, but WI-38VA13A cells continued active DNA synthesis and mitosis in medium with 0.1% serum to form 16 20 layers of cells (191-239 x 10(6) cells per T-75 flask) in 27 days. WI-38VA13A cells ceased proliferation and became nonviable rapidly in serumless medium. PMID- 4306787 TI - Inorganic pyrophosphatase of rat liver mitochondria. Correlation of latency with catalytic properties and intramitochondrial location. AB - Stimulation of Mg(2+)-dependent inorganic pyrophosphatase activity several fold by disruption of mitochondrial membranes does not appreciably alter the catalytic properties of the enzyme. Stimulation is due to increased accessibility of substrate to the enzyme, which is not solublized on activation. The enzyme is attached to the inside of the inner membrane, and under physiological conditions probably hydrolyzes only intramitochondrially-produced PP(i). PMID- 4306788 TI - Enzyme cytochemistry of gastric parietal cells at a fine structure level. Cytochemical separation of the endoplasmic reticulum from the "tubulovesicles". PMID- 4306790 TI - Amoebic meningo-encephalitis. PMID- 4306789 TI - Correlated morphometric and biochemical studies on the liver cell. II. Effects of phenobarbital on rat hepatocytes. AB - The changes occurring in rat hepatocytes during a 5 day period of treatment with phenobarbital were determined by morphometric and biochemical methods, particular attention being paid to the endoplasmic reticulum. The hepatocytic cytoplasm played an overwhelming part in the liver hypertrophy, while the hepatocytic nuclei contributed to only a moderate extent. The endoplasmic reticulum accounted for more than half of the increase in cytoplasmic volume. The increase in the volume and number of hepatocytic nuclei in the course of phenobarbital treatment was associated with changes in the ploidy pattern. Until the 2nd day of treatment both the rough-surfaced endoplasmic reticulum (RER) and the smooth-surfaced endoplasmic reticulum (SER) participated in the increase in volume and surface of the whole endoplasmic reticulum (ER). Subsequently, the values for RER fell again to control levels, whereas those for SER continued to increase, with the result that by the 5th day of treatment the SER constituted the dominant cytoplasmic element. The specific volume of mitochondria and microbodies (peroxisomes) remained constant throughout the duration of the experiment, while that of the dense bodies increased. The specific number of mitochondria and microbodies displayed a significant increase, associated with a decrease in their mean volume. The phenobarbital-induced increase in the phospholipid and cytochrome P 450 content of the microsomes, as well as in the activities of microsomal reduced nicotinamide-adenine dinucleotide phosphate-cytochrome c reductase and N demethylase, was correlated with the morphometric data on the endoplasmic reticulum. PMID- 4306791 TI - Nuclear magnetic resonance study of the interaction between acetylcholine and horse serum cholinesterase. PMID- 4306792 TI - A mechanism for the action of penicillamine in the treatment of Wilson's disease. PMID- 4306793 TI - Effect of pyrophosphate on hydroxyapatite and its implications in calcium homeostasis. PMID- 4306794 TI - The pyridine nucleotide cycle. PMID- 4306795 TI - Estimation of angiotensin in blood by the preparation of isotopic derivatives. PMID- 4306796 TI - Renin and euryhalinity in the Japanese eel, Anguilla japonica. PMID- 4306797 TI - Aldolase C in brain tumour. PMID- 4306798 TI - Improved graft survival after treatment with Bordetella and anti-lymphocyte serum. PMID- 4306799 TI - Increased yields of stomatitis virus from hamster cells injected with mycoplasma. PMID- 4306800 TI - Tumors of the jaws in Korea. Report of 157 cases. PMID- 4306801 TI - Localization of the cardiac sympathetic synapses in the dog. PMID- 4306802 TI - Effect of inhibitors of protein synthesis on renal pressor factors. PMID- 4306803 TI - Different cell culture characteristics of two strains of murine sarcoma virus. PMID- 4306804 TI - Dissociation of multiple polyoma virus functions by ultraviolet irradiation. PMID- 4306805 TI - Effect of angiotensin on the denervated kidney in the dog. PMID- 4306806 TI - Inhibition of human cytomegalovirus in vitro by double-stranded polyribocytidylic inosinic acid (poly Ir.Cr). PMID- 4306807 TI - 1-methyl-1-nitrosourea depression of brain nicotinamide adenine dinucleotide in the production of neurologic toxicity. PMID- 4306808 TI - Plaque assay of Herpesvirus hominis on human embryonic fibroblasts. PMID- 4306809 TI - The prevention of acute renal failure in the rat by long-term saline loading: a possible role of the renin-angiotensin axis. PMID- 4306811 TI - A comparison of immune cytolysis and virus-induced fusion of sensitive and resistant cell types. PMID- 4306810 TI - Interferon and resistance to upper respiratory virus illness. PMID- 4306812 TI - [Physiopathology of renovascular hypertension]. PMID- 4306813 TI - Structural and functional properties of Escherichia coli DNA polymerase. PMID- 4306814 TI - Joining of DNA strands by DNA ligase of E. coli. PMID- 4306815 TI - Enzymes involved in the early stages of repair of ultraviolet-irradiated DNA. PMID- 4306816 TI - On the mechanism of the polynucleotide joining reaction. PMID- 4306817 TI - DNA replication in vitro. I. Synthesis of single-stranded phi X174 DNA in crude lysates of phi X-infected E. coli. PMID- 4306819 TI - Cardiac output and postganglionic sympathetic activity during acute respiratory alkalosis. PMID- 4306818 TI - The state of the DNA of polyoma virus and SV40 in transformed cells. PMID- 4306820 TI - The effects of nondepolarizing relaxants and anticholinesterases on the neuromuscular refractory period of anesthetized man. PMID- 4306821 TI - Prenarcotic doses of barbiturates as an aid in localizing diseased brain tissue. PMID- 4306822 TI - Malic dehydrogenase isoenzymes in green stem tissue of Opuntia: isolation and characterization. PMID- 4306824 TI - [Cytochrome oxidase solubilization at high pH. I. Effects of pH, Ca2+ and Mg2+ on the reversible solubilization of cytochrome oxidase and cytochrome b by synthetic zeolites and by EDTA]. PMID- 4306823 TI - Properties of an adenyl cyclase partially purified from frog erythrocytes. PMID- 4306825 TI - Cytochrome oxidase solubilization at high pH. II. Separation and partial isolation of cytochrome oxidase from beef heart mitochondria without use of detergents or sonic oscillations. PMID- 4306826 TI - Restoration of gluconeogenesis in biotin-deficient rats. PMID- 4306828 TI - On the mycobactericidal effect of the interaction isoniazid--copper. PMID- 4306827 TI - Phosphatidylinositol kinase in rat kidney cortex. II. Subcellular distribution and kinetic properties. PMID- 4306829 TI - [Virus excretion in equine abortion (rhinopneumonitis)]. PMID- 4306830 TI - [Experimental contributions to the knowledge of dermatitis pustulosa in sheep. I. Attempt to purify the dermatitis pustulosa virus and to separate the complement fixating antigens from the elementary bodies]. PMID- 4306831 TI - [Experimental contributions to the knowledge of the dermatitis pustulosa in sheep. II. The behavior of the complement fixating and the infectious antigens in various pH-ranges]. PMID- 4306832 TI - [On the occurrence of inclusion rhinitis in a stock of swine]. PMID- 4306834 TI - Growth characteristics of rhinoviruses in human gingival cells. PMID- 4306833 TI - [Studies on the nucleic acid metabolism of monkey kidney cell cultures after infection with SV 40. V. Virus replication during inhibition of cellular DNA synthesis]. PMID- 4306835 TI - Simultaneous rise in complement-fixing antibodies against herpesvirus hominis and varicella-zostervirus in patients with chickenpox and shingles. PMID- 4306836 TI - Establishment, steady state and cure of a chronic infection of LLC cells with West Nile virus. PMID- 4306837 TI - Basal urinary pyrophosphate excretion in pseudogout. PMID- 4306838 TI - Regulation of the enzymes involved in the biosynthesis of 2,3-dihydroxybenzoic acid in Aerobacter aerogenes and Escherichia coli. PMID- 4306839 TI - The action of crystalline lactate dehydrogenase from rabbit muscle on glyoxylate. PMID- 4306840 TI - The incorporation of [2-14C]glycine and delta-amino[4-14C]-laevulinic acid into the prosthetic groups of cytochrome oxidase and other cytochromes in yeast adapting to oxygen. PMID- 4306841 TI - Mechanism of puromycin activation of tadpole liver glycogen synthetase. PMID- 4306842 TI - Nucleotide inhibition of adenyl cyclase activity in fat cell membranes. PMID- 4306843 TI - The effect of gonadotropins on testicular adenyl cyclase. PMID- 4306844 TI - On the deposition and utilization of inorganic pyrophosphate in Tetrahymena pyriformis. PMID- 4306845 TI - The photocatalytic action of adsorbed riboflavin. PMID- 4306846 TI - Carbenoid intermediates from the photolysis of haloalkylcobalamins. PMID- 4306847 TI - Survey of pyridine nucleotide metabolism in Tetrahymena pyriformis. PMID- 4306848 TI - Electron paramagnetic resonance spectra of some vitamin B 12 derivatives. PMID- 4306849 TI - Nicotinamide-adenine dinucleotide photoreduction in Rhodospirillum rubrum chromatophores. PMID- 4306850 TI - Reactivity of Anacystis nidulans cytochrome c-554 with cytochrome oxidases. PMID- 4306852 TI - The effect of glucose on the electron-transport systems of the aerobic bacteria Azotobactervinelandii and acetobacter suboxydans. PMID- 4306851 TI - Effect of anions on oxidative phosphorylation in submitochondrial particles. PMID- 4306853 TI - Distribution of alpha-tocopherol in beef heart mitochondria. PMID- 4306855 TI - [Antigenic properties of a "Graffi" pseudotype of the murine rhabdomyosarcoma virus (MSV)]. PMID- 4306854 TI - Liver transplantation in man--3, Studies of liver function, histology, and immunosuppressive therapy. AB - The experience gained from 13 hepatic transplant operations is described, with particular reference to the findings in nine patients who survived the immediate operative period. A major problem was found to be infection. Fulminant pneumonia caused death in two adults, at a time when liver function was virtually normal. Infection related to bile fistula and sepsis may be overcome by an improved method of biliary drainage by cholecyst-dochostomy, which was carried out in the last two patients. Jaundice in the second week due to rejection was observed in several patients. The striking histological change was centrilobular cholestasis. The jaundice, which was not prevented by administration of antilymphocyte globulin, was rapidly controlled by temporarily increasing die dose of prednisone. One patient who survived for four and a half months and who had a poor tissue match subsequently developed chronic rejection with progressive cholestatic jaundice. Five of the patients were able to go home and at time of publication two are alive and well 14 and 20 weeks after treatment. PMID- 4306856 TI - [Morphologic cell transformation and virus replication after in vitro infection of human cells with Moloney strain murine sarcoma virus]. PMID- 4306857 TI - [Heterotransmission of avian myeloblastoma virus (AMV) to the hamster]. PMID- 4306858 TI - The effect of vasoactive drugs on local coronary flow. PMID- 4306859 TI - The quantitative determination of bile salts in bile using thin-layer chromatography and 3 alpha-hydroxysteroid dehydrogenase. PMID- 4306860 TI - [On the action of ouabain-, nicotini acid- and potassium-free incubation media on the ACTH stimulated lipolysis in isolated fat cells]. PMID- 4306861 TI - A simple rapid method for the determination of total nitrogen in urine. PMID- 4306862 TI - [Serological findings in primary chronic polyarthritis]. PMID- 4306863 TI - [On the mechanism of the effect of deoxycorticosterone on the transmission of excitation in sympathetic ganglia]. PMID- 4306865 TI - Deficits in shock-avoidance performance after amygdala-hippocampus separation. PMID- 4306864 TI - [Nervous influences on the activity of the adrenal cortex]. PMID- 4306866 TI - An electron microscopic study of target fibers, target-like fibers and related abnormalities in human muscle. PMID- 4306867 TI - Comparison and analysis of the teratogenic effects of serotonin, angiotensin-II, and bradykinin in mice. PMID- 4306868 TI - Studies on mechanism of action of salicylates. V. Effect of salicylic acid on enzymes involved in mucopolysaccharides synthesis. PMID- 4306869 TI - Adenosine 3',5'-monophosphate-dependent protein kinase from brain. PMID- 4306871 TI - Toxicity of parathion, systox, octamethyl pyrophosphoramide, and methyl parathion in man. PMID- 4306870 TI - A study of the measurement of cholinesterase by constant-pH titration: the effect of hemolysins and a comparison with the electrometric technique. PMID- 4306872 TI - [Changes in the lungs following radiation therapy of patients with cancer of the mammary glands]. PMID- 4306873 TI - [The effect of irradiation and neonatal thymectomy on the growth of polyoma tumors in rabbits]. PMID- 4306874 TI - [Patterns in the growth of rat and hamster embryo tissue cultures under normal conditions and after polyoma virus transformation]. PMID- 4306875 TI - [Immunologic characteristics of a virus inducing resistance to Rous virus in chick embryo cultures]. PMID- 4306876 TI - [On the pathomorphology of tumors induced by benzocholine 69]. PMID- 4306878 TI - [On various toxigenic properties of Cl. perfringens types D and E]. PMID- 4306877 TI - [The use of antibiotics in otologic practice]. PMID- 4306879 TI - [Complement fixing antibodies to adenoviruses in children with infectious hepatitis]. PMID- 4306880 TI - [Electron-microscopic study of the secretion of the toxin of Cl. perfringens by means of specific ferroglobulin]. PMID- 4306881 TI - [The effect of acute respiratory virus diseases on antibody formation in dysentery in children at an early age]. PMID- 4306882 TI - The susceptibility of some Australian fauna to infection with foot and mouth disease virus. PMID- 4306883 TI - A comparison of the pharmacology of the isolated rabbit ear and its central artery. PMID- 4306884 TI - Changes of nuclear RNA in hepatomas as revealed by RNA-DNA hybridization. PMID- 4306885 TI - ACTH and decubitus ulceration: an experimental study. AB - 1. Ulcers due to neurectomy with excision of the sciatic nerve are more severe than those due to tenotomy and can be inhibited by a single dose of ACTH.2. Timing and mode of administration of ACTH to prevent decubitus ulceration is critical and depends on its ability to prevent the separation of endothelial cells. PMID- 4306886 TI - Muscarinic component of splanchnic-adrenal transmission in the dog. AB - 1. The effect of atropine on catecholamine release evoked by stimulation of the splanchnic nerve was studied in the adrenal medulla of the dog. The magnitude of the catecholamine release was estimated biologically on the basis of the pressor response occurring in the perfused and acutely sympathectomized hindquarters of the same dog by comparing it with responses elicited by intravenous injection of adrenaline.2. Atropine reduced the responses to nerve stimulation, and appeared to have a more prominent effect on the responses elicited by stimulation at moderate frequency (10 pulses/sec).3. Hexamethonium or nicotine caused a more powerful, but not complete, blockade of transmission; the subsequent injection of atropine caused a further inhibition of the residual responses, leading to a complete, or near complete, abolition of the release by nerve stimulation.4. The data were taken as evidence that transmission of impulses through muscarinic receptors occurs in normal conditions in the adrenal medulla of the dog, though this type of transmission is less prominent than that through nicotinic receptors. PMID- 4306887 TI - The action of general anaesthetic agents on root responses of the frog isolated spinal cord. AB - 1. The action of volatile and barbiturate general anaesthetic agents on synaptic transmission in the frog isolated spinal cord has been studied by recording ventral root synaptic potentials and spike discharges evoked by volleys in a dorsal root and in the lateral column fibres.2. Some observations on the distribution of the lateral column fibres and the characteristics of the dorsal root potentials have been presented.3. Volatile agents depressed and eventually abolished all components of the ventral root responses. Failure of motoneurone discharge was the result of two factors, a decrease in the slope of the synaptic potential and an elevation of the critical depolarization required to trigger propagated impulses.4. Barbiturate compounds, in contrast, readily abolished polysynaptic components of the ventral root responses, but the short latency discharge produced by lateral column stimulation was potentiated, and was accompanied by a lowering of the firing threshold of motoneurones. The mechanism of this potentiation by barbiturate compounds is discussed.5. It is concluded that volatile agents act predominantly on the initial segment and subsynaptic elements of the motoneurone, whereas barbiturate compounds depress the presynaptic or postsynaptic components of interneuronal synapses. PMID- 4306889 TI - Benzoyl esterases of fungi. PMID- 4306888 TI - The effect of metals on the S-S polypeptide receptor in depolarized rat uterus. AB - 1. Metals potentiate the contractile effects of S-S polypeptides in depolarized rat uterus. Their order of potency is Co(++)>/=Co(+++)>/=Mn(++)>/=Ni(++)>/= Mn(+++)>Zn(++)>/=Mg(++)>Fe(++)>Fe(+++)>/= Ca(++)>Be(++)=Sr(++)=Ba(++)=Cu(++)=O.2. S-S polypeptides with relatively weak oxytocic activity such as lys-vasopressin, arg-vasopressin and orn-vasopressin are strongly potentiated by metals while highly active polypeptides such as oxytocin are weakly potentiated.3. Potentiation by metals was specific for S-S polypeptides; other polypeptides (bradykinin, hypertensin) as well as acetylcholine and isoprenaline were unaffected.4. Potentiation by metals occurs rapidly and is fully reversible. In all cases some activity was retained by S-S polypeptides even in the complete absence of metals.5. A scheme which could account for the observed effects has been formulated. This assumes the formation of a ternary complex between receptor, metal and polypeptide leading to improved alignment between polypeptide and receptor.6. Analogies are discussed between metal enzymes and the S-S polypeptide receptor for which the term metal receptor is proposed. PMID- 4306891 TI - Manganese in the fresh water clam. PMID- 4306890 TI - Estrogen conjugates of hen's urine. PMID- 4306892 TI - [On myeloplaxic tumor of the synovial membrane of the knee (clinical, histomorphological and histochemical study)]. PMID- 4306893 TI - Noradrenergic rather than serotonergic basis of reward in the dorsal tegmentum. PMID- 4306894 TI - Collagenase production by human dermis in vitro. PMID- 4306895 TI - Lateral inhibition in a motor output system. I. Reciprocal inhibition in Dipteran flight motor system. PMID- 4306896 TI - Lateral inhibition in a motor output system. II. Diverse forms of patterning. PMID- 4306897 TI - Organization of the retina of the mudpuppy, Necturus maculosus. II. Intracellular recording. PMID- 4306898 TI - Discharge patterns of brain-stem respiratory neurons during Hering-Breuer reflex evoked by lung inflation. PMID- 4306899 TI - Some possible neural correlates of combination tones. PMID- 4306900 TI - Time course of minimal corticomotoneuronal excitatory postsynaptic potentials in lumbar motoneurons of the monkey. PMID- 4306901 TI - Block of arachnoid villus by subarachnoid hemorrhage. PMID- 4306902 TI - Inhibition of norepinephrine uptake in hearts by angiotensin II and analogs. PMID- 4306903 TI - Selective augmentation of the pressor responses to catecholamines by metanephrine. PMID- 4306904 TI - Influence of d-tubocurarine, decamethonium and succinylcholine on repetitively evoked end-plate potentials. PMID- 4306905 TI - Effects of alpha,alpha'-bis-(dimethylammoniumacetaldehyde diethylacetal)-p,p' diacetylbiphenyl bromide (DMAE) on neuromuscular transmission. PMID- 4306906 TI - Antimicrobial prophylaxis. PMID- 4306907 TI - Function of the pancreatic B-cells in hamsters bearing a transplantable islet cell tumor. PMID- 4306908 TI - Concentration of the virus of foot and mouth disease by foam flotation. PMID- 4306910 TI - Fundamentals of mammographic diagnoses of benign and malignant diseases. PMID- 4306909 TI - [Effects of a vasopressin-corticoid association in patients having an astrocytoma or cerebral metastasis. Evolutive study using complementary methods]. PMID- 4306911 TI - [Cortisone therapy syntonized with the circadian rhythm of the cortico-adrenal incretion]. PMID- 4306912 TI - [Occupational allergy to protein hormones in the pharmaceutical industry]. PMID- 4306913 TI - [Water and electrolyte metabolism in the kidney, with special reference to the third factor]. PMID- 4306914 TI - The absence of "heme-heme" interactions in hemoglobin. PMID- 4306915 TI - Tumor-specific antigens detected by inhibition of macrophage migration. AB - Tumor-specific antigens of a guinea pig hepatoma induced by diethylnitrosamine were detected by the inhibition of migration of specifically sensitized macrophages from capillary tubes, and by the local passive transfer of delayed skin hypersensitivity and the suppression of growth of intradermally same injected tumor. PMID- 4306916 TI - Virus-like antigen, antibody, and antigen-antibody complexes in hepatitis measured by complement fixation. AB - Complement fixation techniques are described for measuring a virus-like antigen associated with viral hepatitis. Antigen was found in the blood of 98 percent of 130 patients, with the serum form of hepatitis, from whom multiple samples were obtained. Antibodies arising during hepatitis are usually combined with antigen and cause anticomplementary activity in the serum, which is reversible with excess antigen or antibody. Tests for antigen and specific anticomplementary activity can be used diagnostically and to screen blood donors for hepatitis carriers. PMID- 4306917 TI - Radiation leukemia virus: quantitative tissue culture assay. AB - Radiation leukemia virus does not propagate in tissue cultures from either Swiss or C57BL mouse embryos, but it does augment focus formation by the defective Moloney leukemia pseudotype of murine sarcoma virus in Swiss mouse cells and thus can be quantitatively assayed. PMID- 4306918 TI - [Congenital malformations of the coronary arteries and their treatment]. PMID- 4306920 TI - Function of sympathetic nerves in blood vessels. PMID- 4306919 TI - [Contribution on the functional morphology of the neurohypophysis. 3. On the influence of corticoid or ACTH treatment on the appearance of "gomori-positive" granules in the outer layer of the median eminence in rats and mice following bilateral adrenalectomy of hypophysectomy]. PMID- 4306921 TI - Tumors of the new born. PMID- 4306922 TI - Importance of minor salivary gland tumors for the general practitioner. PMID- 4306923 TI - [Physical properties of polymethyl methacrylates filled with silicica gel for dental materials]. PMID- 4306924 TI - Chylous ascites. Management with medium-chain triglycerides and exacerbation by lymphangiography. PMID- 4306925 TI - Granular cell myoblastoma of the common bile duct. PMID- 4306926 TI - Angiography of the gastrointestinal tract: results and experience. PMID- 4306927 TI - Uterosalpingography. PMID- 4306928 TI - Mixed mesodermal tumors. PMID- 4306930 TI - [Chromatography on silica gel cylinders. Technic and applications]. PMID- 4306929 TI - Herpes simplex. Clinical aspects and electron microscopic findings. PMID- 4306932 TI - Chromatography of cyclic 3'5'-adenosine monophosphate on silica gel glass microfiber sheets. PMID- 4306931 TI - Non-fatal Clostridium perfringens bacteremia. PMID- 4306933 TI - 2-(alkyl- and arylamino)-5-nitrothiazole derivatives with antiamebic, antitrichomonal, and antimalarial properties. PMID- 4306934 TI - [Clinical and experimental observations on so-called polyneuritis caused by tricresylphosphates]. PMID- 4306936 TI - [A manual mechanical injector with timer and radiopaque indicator]. PMID- 4306935 TI - Studies on adrenal cortical function in patients with lung cancer. PMID- 4306937 TI - Secretin-like choleresis produced by a diarrheogenic non-beta islet cell tumor of the pancreas. PMID- 4306938 TI - Immunologic and virus studies with human sarcomas. PMID- 4306939 TI - Renal cortical tumors: a 40-year statistical study. PMID- 4306941 TI - [The functional state of the cerebral vessels in supratentorial tumors]. PMID- 4306940 TI - [The significance of stato-kinetic disorders in the diagnosis of tumors of the parietal lobes]. PMID- 4306942 TI - [Diagnostic importance of cutaneous electrophoretic tests in the clinical picture of brain tumors]. PMID- 4306943 TI - Aspiration biopsy of salivary gland tumors. IV. Morphologic studies on smears and histologic sections from 45 cases of adenoid cystic carcinoma. PMID- 4306944 TI - Effect of raphanin on the multiplication of some RNA and DNA viruses in, and interferon production by, cultured cells. PMID- 4306945 TI - [On the problem of extracranial "metastasizing" of gliomas through implantation]. PMID- 4306946 TI - [Data from follow-up after parotid gland tumor operations]. PMID- 4306947 TI - [A case of pharyngeal synovioma]. PMID- 4306948 TI - Primary hepatoma in Uganda. A prospective clinical and epidemiologic study of forty-six patients. PMID- 4306949 TI - [Tumor of the glomus caroticum and carotid artery anomaly]. PMID- 4306950 TI - [Dynamics and contractility of the left ventricle]. PMID- 4306951 TI - Tetraphenylborate stimulation of phospholipid labeling in goldfish brain. PMID- 4306952 TI - Solubilization of a neutral phenazyl free radical by DNA. PMID- 4306953 TI - Electron paramagnetic resonance of nitric oxide cytochrome C. PMID- 4306954 TI - Action of 3',5'-cyclic adenosinemonophosphate on the protein synthesizing capacity of thyroid polyribosomes in vitro. PMID- 4306955 TI - Adenyl cyclase in human platelets: activity and responsiveness. PMID- 4306956 TI - Assignment of tryptophan indole NH proton resonances of lysozyme. PMID- 4306957 TI - Rapidly oxidizable equivalents in the terminal portion of the respiratory chain of uncoupled rat liver mitochondria. PMID- 4306958 TI - The enzymic degradation of 3',5' cyclic AMP in strains of E. Coli sensitive and resistant to catobolite repression. PMID- 4306959 TI - Effects of deoxyfrenolicin on isolated adipose cells. I. Glucose and fructose utilization. PMID- 4306960 TI - Comparison of assay methods for studying O,O-diethyl, O-p-nitrophenyl phosphate (paraoxon) detoxication in vitro. PMID- 4306961 TI - Studies with tryptophan metabolites in vitro. 3. The effect of schistosomicidal drugs on kynureninase and kynurenine transaminase of normal mouse liver. PMID- 4306962 TI - Inhibiting effect of angiotensin on potassium accumulation of adrenal cortex. PMID- 4306963 TI - Hormone-secreting tumours of the pancreas. PMID- 4306964 TI - [Surveillance of patients wearing cardiac pacemakers]. PMID- 4306965 TI - Biosynthesis of lipids in subcellular fractions of frog liver. PMID- 4306967 TI - A relationship between ionic environment and hormonal activation of phosphorylase in an insect. PMID- 4306966 TI - The bursa of fabricius and adrenal cortical activity of Gallus domesticus. PMID- 4306968 TI - [Electromyographical and clinical correlations in the evolution of traumatic lesions of peripheral nerves]. PMID- 4306969 TI - Hypnic physiological myoclonias in man: an EEG-EMG study in normals and neurological patients. PMID- 4306970 TI - A segmental neurocutaneous manifestation. Report of a case of nevus unius lateralis and unilateral hypotrophy. PMID- 4306971 TI - Selective inhibition of bacterial enzymes by free fatty acids. AB - Octanoic acid inhibits, in vitro, the bacterial enzymes glucose-6-phosphate dehydrogenase, phosphofructokinase, pyruvate kinase, fumarase, lactate dehydrogenase, and the malic enzyme of Arthrobacter crystallopoietes. The free fatty acid appears to act as an inhibitor of lipogenesis, although it does not affect the rate of gluconeogenesis. To demonstrate that this inhibition may be of physiological significance in vivo, those enzymes not involved in lipogenesis, such as fructose-1, 6-diphosphatase, phosphoglucomutase, phosphohexoisomerase, aconitase, nicotinamide adenine dinucleotide phosphate (NADP) isocitrate dehydrogenase, NADP glutamate dehydrogenase, malate dehydrogenase, and isocitrate lyase, were assayed and found not to be inhibited by the free fatty acid. PMID- 4306972 TI - Recent microbiological studies with gentamicin. PMID- 4306973 TI - Use of gentamicin in combinations with other antibiotics. PMID- 4306974 TI - Sensitivity tests of klebsiella, enterobacter, and serratia. PMID- 4306975 TI - Nephrotoxicity of aminoglycosides and gentamicin. PMID- 4306977 TI - Experiences with the new antibiotic gentamicin. PMID- 4306976 TI - Gram-negative rod bacteremia. PMID- 4306978 TI - [Malignant ethmoid bone tumors in woodworkers]. PMID- 4306979 TI - [Early EEG in brain tumors]. PMID- 4306980 TI - A potentiating-factor-dependent neutralizing antibody in calves and rabbits against bovine parainfluenza 3 virus. PMID- 4306981 TI - [Effect of cyclic adenosine-3',5'-monophosphate (3',5'-AMP) and its dibutyryl derivative (DBA) on lipolysis, glycogenolysis and corticosterone synthesis]. PMID- 4306982 TI - Carcinomatous cerebellar degeneration, encephalomyelitis, and sensory neuropathy (radiculitis). Report of a case incorporating both purely degenerative and intense inflammatory changes, with special prominence of the latter in the putamen. PMID- 4306983 TI - [Rheumatoid polyarthritis and chronic lymphoid leukemia. Studies of 7 cases of association of these 2 diseases]. PMID- 4306984 TI - [Forms of passage between Fiessinger-Leroy-Reiter oculo-urethro-synovitis and psoriatic rheumatism. (Apropos of 7 personal cases)]. PMID- 4306985 TI - [The arthropathies of hemochromatosis. Results of a prospective study of 54 patients]. PMID- 4306987 TI - [Treatment of common sciatica]. PMID- 4306986 TI - [Absorption of H3-labelled vitamin D3 in nutritional osteomalacia]. PMID- 4306988 TI - [Pelvic spondylarthritic involvement in Fiessinger-Leroy-Reiter rheumatism]. PMID- 4306990 TI - [Alveolar proteinosis. 2 cases with ultrastructural study]. PMID- 4306989 TI - [Ligature of the intestinal lymphatics and arteriosclerosis (26 months' experience)]. PMID- 4306991 TI - [Milk intolerance syndrome and decrease of lactase activity of the small intestine]. PMID- 4306993 TI - [Serum folic acid activity in fatty liver and alcoholic cirrhosis]. PMID- 4306992 TI - ["Safari fever". Apropos of 18 cases of bilharzic invasion]. PMID- 4306994 TI - [Late sequelae of splenectomy in chronic primary splenomegaly]. PMID- 4306995 TI - [Prevention of pregnancy nephropathies]. PMID- 4306996 TI - [Disorders in left ventricle repolarization during acute cytosteatonecrotic pancreatitis. Electrocardiographic course under the effect of antienzymes]. PMID- 4306997 TI - [Neurophysiologic study of the psychomotor effect of a drug: apropos of bulcocapnine catatonia]. PMID- 4306998 TI - [Behavioral and neurophysiological study of the effect of LSD 25 in the monkey]. PMID- 4306999 TI - [Polygraphic study of "sleep" induced by sodium gamma hydroxybutyrate and diazepam]. PMID- 4307001 TI - [Clinical electroencephalography and psychotropic substances]. PMID- 4307000 TI - [An original psychotropic drug: sulpiride]. PMID- 4307002 TI - [Apropos of some electroencephalographic aspects of the action of psychotropic drugs]. PMID- 4307003 TI - [Clinical practice and research: prospects of the work of the psychologist in psychiatry]. PMID- 4307004 TI - [Digestive intolerance to cereal flour in adults and its prevention by a new method of flour predigestion]. PMID- 4307005 TI - [The practitioner and the expert testimony]. PMID- 4307006 TI - [Therapeutic effect of alpha-tocopher- yl-quinone on muscular disorders of hyperthyroidism and of prolonged treatment by corticoids and antimitotics]. PMID- 4307007 TI - Viruses and embryos. PMID- 4307008 TI - [Cultivation of viruses in a suspension of continuous cells]. PMID- 4307009 TI - [The use of quantitative counts of cytomorphologic changes for the characterization of the infectious process induced by adenoviruses in tissue culture. 2. An objective method of determining the infective titer of adenoviruses and of antibodies neutralizing them]. PMID- 4307011 TI - [Morphogenesis of Sendai virus in Ehrlich ascites carcinoma cells]. PMID- 4307012 TI - [The use of polyethyleneglycol for virus concentration]. PMID- 4307013 TI - [Cultivation of hamster Rous sarcoma cells]. PMID- 4307010 TI - [Humoral factors of immunity to adenoviruses in term and premature children during the course of the first year of life]. PMID- 4307014 TI - Activation of a virus integrated with the cell genome during fusion of cells and the formation of heterokaryons. PMID- 4307015 TI - [Amoebic abscess of the liver]. PMID- 4307016 TI - [Coexistence of an early mucinous cancer with Menetrier's disease]. PMID- 4307017 TI - [Folliculoma of the right ovary]. PMID- 4307018 TI - [Acute-phase protein in neoplastic diseases in children]. PMID- 4307019 TI - Pharmacology of motor nerve terminals. PMID- 4307022 TI - [Ultrastructural and enzymohistochemical observations on renal carcinoma. Correlative and histogenetic study]. PMID- 4307021 TI - In vivo therapy of oncogenic viruses. PMID- 4307023 TI - Peripheral and central phenomena of post-epileptic extinction. PMID- 4307024 TI - Experimental lead neuropathy: a disease of the supporting cells in the peripheral nervous system. PMID- 4307025 TI - Virilizing tumors of the adrenal gland in childhood: report of eight cases. PMID- 4307020 TI - Central synaptic transmission--microelectrophoretic studies. PMID- 4307026 TI - Glioblastoma multiforme. PMID- 4307027 TI - Requirement of a stable secondary structure for the antiviral activity of polynucleotides. PMID- 4307028 TI - Stimulation of DNA synthesis in resting stage human fibroblasts after infection with Rous sarcoma virus. PMID- 4307029 TI - In vitro production of angiotensin I by renal glomeruli. PMID- 4307030 TI - Adenoviruses. PMID- 4307031 TI - Further electron microscopic studies of E. histolytica. PMID- 4307032 TI - Cytochemical observations on Plasmodium berghei and P. gallinaceum. PMID- 4307033 TI - Solid-phase peptide synthesis. PMID- 4307035 TI - Factors affecting recombination of lactate dehydrogenase isoenzyme subunits. PMID- 4307034 TI - Neurosecretion. PMID- 4307036 TI - Enzymatic phosphorylation of D-sedoheptulose with animal liver. PMID- 4307037 TI - The chemotherapy of enterobacterial infections. PMID- 4307038 TI - An E.S.R. study of an X-irradiated single crystal of 5-iododeoxyuridine. PMID- 4307039 TI - E.S.R. study of x-irradiated single crystals of 5-bromodeoxyuridine and 5 iododeoxyuridine. PMID- 4307041 TI - Plasma corticotrophin levels in primary and secondary adrenocortical insufficiency. PMID- 4307040 TI - Hemoproteins in anaerobically grown yeast cells. PMID- 4307042 TI - Influence of HCG on the production of oestrogens by the adrenal gland. PMID- 4307044 TI - Dissociation between production and storage of corticotrophin-releasing factor. PMID- 4307043 TI - Cyclic 3',5'-AMP and ovarian ascorbate depletion. PMID- 4307045 TI - Effect of bromide on evoked release of monoamines from brain slices and intact atria. PMID- 4307046 TI - Metabolism of the angiotensins in isolated perfused tissues. PMID- 4307047 TI - Removal of angiotensin by isolated perfused organs of the rat. PMID- 4307048 TI - Angiotensin accelerates catecholamine biosynthesis in sympathetically innervated tissues. PMID- 4307049 TI - [Allergic encephalitis in a child associated with adenoviral infection]. PMID- 4307050 TI - [Malignant tumors of the liver in children]. PMID- 4307051 TI - Electron spin resonance in biological tissues. PMID- 4307052 TI - Temperature and saturation effects in the ESR spectra of whole tissues. PMID- 4307053 TI - Pharmacological aspects of the coronary circulation. PMID- 4307055 TI - Acetylcholine facilitation, atropine block of synaptic excitation of cortical neurons. AB - Sinigle neurons in cat visual cortex were driven by afferent stimuli to determine the effects of drugs liberated from multibarreled micropipettes on synaptic transmission. Acetylcholine increased, and atropine decreased, the number of neuron discharges fired in response to stimulation of the mesencephalic reticular formation without necessarily affecting responses to other stimuli or affecting spontaneous firing. PMID- 4307056 TI - 25-hydroxycholecalciferol: direct effect on calcium transport. AB - The perfused small intestine from a vitamin D deficient rat exhibits about one half the calcium transport of the intestine from a rat given vitamin D. These levels of calcium transport can be maintained for at least 4 hours. Addition of 2.5 micrograms of 25-hydroxycholecalciferol added to the vitamin D deficient intestine via the arterial blood perfusate induces a rise in calcium transport to +D levels within 2 hours. In contrast, 250 micrograms of vitamin D(3) given in the same manner has no effect on the calcium transport level overa 4-hour period. These data provide strong evidence that 25-hydroxycholecalci ferol represents the metabolically active form of vitamin D(3). PMID- 4307054 TI - The mechanism of action of some antibacterial agents. PMID- 4307057 TI - Islet cell tumors of the pancreas. PMID- 4307058 TI - Clinicopathological conference...cirrhosis and bloody ascites. PMID- 4307059 TI - [On the role of lecithinase C in creating immunity to gas gangrene under experimental conditions]. PMID- 4307060 TI - [Toxin formation by Cl. perfringens type E]. PMID- 4307061 TI - Ultrastructure of multiple pancreatic tumors in a case of Zollinger-Ellison syndrome. PMID- 4307062 TI - Initial high dose irradiation for metastases causing spinal cord compression in children. PMID- 4307064 TI - Appearance of the transverse sinuses by brain scanning. PMID- 4307063 TI - Jugular venography. PMID- 4307065 TI - Consumption coagulopathy and acute renal failure due to gram-negative septicemia after abortion. Complete recovery with heparin therapy. PMID- 4307067 TI - The period and nature of hazard in clinical renal transplantation. I. The hazard to patient survival. PMID- 4307066 TI - The period and nature of hazard in clinical renal transplantation. II. The hazard to transplant kidney function. PMID- 4307068 TI - [Sensory conduction velocity and biopsy findings on the sural nerves in neuropathy]. PMID- 4307069 TI - The activity of oxidative enzymes in short-term explant cultures of gliomas in vitro. I. Coenzyme I-bound dehydrogenases and succinate dehydrogenase. PMID- 4307070 TI - Recording of nerve potential. PMID- 4307071 TI - Erythrocyte membrane of Anadara inflata, a marine bivalve mollusc. PMID- 4307072 TI - Laboratory aids in the diagnosis of endocrine disorders. PMID- 4307073 TI - Cytogenetics and abortion. PMID- 4307074 TI - Genetic factors in carcinoma. PMID- 4307075 TI - [Benign stomach tumors, clinical aspects and roentgen picture]. PMID- 4307077 TI - [Perfusion of the isolated liver. Changes in the time of tissue electronic paramagnetic resonance (or ESR, electrospin resonance)]. PMID- 4307076 TI - [Perfusion of the isolated liver. Enzymatic behavior of the cells of the hepatic reticulo-histiocytic system]. PMID- 4307078 TI - Influence of germ-free status on hepatoma induction by 7,12 dimethylbenz(a)anthracene in C3H mice. PMID- 4307080 TI - Electron microscopy of intranuclear inclusions in a mixed tumor. PMID- 4307079 TI - Malignant transformation of hamster cells by cell-free extracts of bovine papillomas (in vitro). PMID- 4307081 TI - Skin temperature of the rabbit ear during degeneration of its sympathetic nerve supply. PMID- 4307082 TI - [Structural characteristics of the sleep of depressed patients]. PMID- 4307083 TI - [Electroclinical correlations in corticotropin therapy of infantile non hypsarrhythmic epilepsy (catamnestic study)]. PMID- 4307084 TI - [Analysis of the various components of the evoked muscular response in some peripheral nerve lesions]. PMID- 4307085 TI - [Electrophysiological data on the damage of the ulnar verve at the elbow in a case of bilateral Mouchet's syndrome]. PMID- 4307086 TI - The formation by the rabbit of N-acetylglucosaminides of steroid phenolic sulfates. PMID- 4307087 TI - Metabolism of 17-alpha-ethynylestradiol and its 3-methyl ether by the rabbit; an in vivo D-homoannulation. PMID- 4307088 TI - [Signal transmission and signal processing by nerve cells]. PMID- 4307089 TI - [Kidney regeneration after temporary ischemia. Biochemical, histochemical, fluorescent-microscopic and histological studies on the nucleic acid and protein metabolism]. PMID- 4307090 TI - Effect of glucagon on rat heart adenyl cyclase. PMID- 4307091 TI - Study on the stability of lysosome membranes. IV. Protection of liver lysosomes from the labilizing effect of chlorpromazine with succinate and glutamate in vivo. PMID- 4307092 TI - Hypothalamo-pituitary-adrenal function in the rat after prolonged treatment with cortisol. AB - 1. Cortisol, administered subcutaneously every day for long periods, caused growth retardation, adrenal atrophy and impaired hypothalamo-pituitary-adrenal (HPA) function in the rat.2. The growth rate and the functional activity of the HPA system gradually returned to normal after steroid withdrawal.3. Normal adrenal sensitivity to corticotrophin returned more rapidly than normal pituitary corticotrophic function, suggesting that the initial impairment of HPA function was due both to reduced responsiveness of the adrenal gland to corticotrophin and failure of the pituitary gland to secrete the hormone. PMID- 4307093 TI - [Contribution to the so-called granular neuroma of the oral cavity]. PMID- 4307094 TI - Pagetoid spread of bronchogenic carcinoma. PMID- 4307095 TI - Debridement of dermal ulcers and decubiti with collagenase. PMID- 4307096 TI - [Unusual epipharyngeal tumors]. PMID- 4307097 TI - [Fractionation of perchloric acid-soluble proteins from the cytoplasmic supernatant of rat liver tissue]. PMID- 4307098 TI - Metabolic action of palmitoylcarnitine on rat liver mitochondria. PMID- 4307099 TI - Changed environmental conditions affecting normal body temperature of mice and its effect on the multiplication of foot and mouth disease virus. PMID- 4307100 TI - A note on an embryonal nephroma met with in a fowl. PMID- 4307101 TI - The structure, stereochemistry and reactions of the guanidine moiety of viomycin. PMID- 4307102 TI - Transformation of chick fibroblast cultures with avian myeloblastosis virus. PMID- 4307103 TI - The investigation of adrenergic metabolism with 7H3-norepinephrine in psychiatric disorders. II. Temporal changes in the distribution of urinary tritiated metabolites in affective disorders. PMID- 4307104 TI - [Hereditary disorders of lipid metabolism. Screening of lipids]. PMID- 4307105 TI - [Adaptation of parainfluenza virus 3 to established cell lines]. PMID- 4307106 TI - [Influence of incubation temperature on the development and some genetic features of Vaccinia and Herpes simplex viruses]. PMID- 4307107 TI - A method for microscopy of the mammary gland in the living mouse. PMID- 4307108 TI - [Poisoning with cyanhydric acid. Clinico-therapeutic considerations and presentation of a case]. PMID- 4307111 TI - [Cytomegalic inclusion disease in megacolon]. PMID- 4307109 TI - The assay of ACTH and the action of ACTH and steroids on corticosteroidogenesis in the mouse. PMID- 4307110 TI - [Circulation of lymphocytes]. PMID- 4307112 TI - [Adrenal function test with Synacthen in children]. PMID- 4307113 TI - [Vascular symptoms of retroperitoneal hemangiopericytoma. Their significance and diagnostic value]. PMID- 4307114 TI - [Arterial involvements in Horton's disease]. PMID- 4307115 TI - [Visceral calcinosis induced by intravenous phosphate perfusions in myelomatous hypercalcemia]. PMID- 4307116 TI - [Thoughts on the lymphographic technic]. PMID- 4307119 TI - [On the use of Presomen in the therapy of urogenital hemorrhages]. PMID- 4307117 TI - [Study of the association of a diuretic and a sympatholitic agent and its application in the treatment of hypertension]. PMID- 4307118 TI - Teratogenic effects of carotid ligation on the developing dentition of the Rhesus monkey. PMID- 4307121 TI - [Various criteria for demonstrating the inter-relationships between bacteria and viruses. II. Changes in the electrophoretic motility of Escherichia coli following the adsorption of various viruses to it]. PMID- 4307120 TI - [Amino acid decarboxylases of Bordetella genus microbes]. PMID- 4307122 TI - [The dynamics of arginine deimidase activity in the process of growth and toxin formation by cultures of Cl. perfringens type A]. PMID- 4307123 TI - Adrenergic neuron blockers and transmitter release after sympathetic denervation studied in the conscious rat. PMID- 4307124 TI - Amoebic dysentery precipitated by corticosteroids. PMID- 4307125 TI - Mental nerve palsy in malignant lymphoma. PMID- 4307127 TI - Medullary cancer of the thyroid gland associated with hypercorticism. PMID- 4307126 TI - Hypoglycemia associated with extrapancreatic tumors. An immunofluorescent study. PMID- 4307128 TI - Mixed tumors of the parotid gland. An ultrastructural study. PMID- 4307129 TI - Cancer of the nasopharynx. Factors influencing prognosis. PMID- 4307130 TI - [Neurogenic tumors of the neck]. PMID- 4307131 TI - [Enzymatic determination of citrate in plasma without deproteinization]. PMID- 4307132 TI - Measurement of renin activity in plasma by a radioimmunoassay for angiotensin I. PMID- 4307133 TI - Accommodation of monosynaptic transmission in spinal motoneurone. PMID- 4307134 TI - [Aspects of adrenal cortex function in obesity. VI. The behavior of aldosterone secretion and secretion of its metabolites during some dynamic tests]. PMID- 4307135 TI - Shunt flow in glioblastoma. Study in regional autoregulation. PMID- 4307136 TI - A hereditary neurological disease with facial spasm. PMID- 4307138 TI - Immunization with inactivated poliovirus vaccine and attenuated type 3 poliovirus. I. Vaccination with the WM3 strain in 20 families. PMID- 4307137 TI - Congenital malformation of the central nervous system associated with genital type (type 2) herpesvirus. PMID- 4307139 TI - Long-term anticoagulant prophylaxis after myocardial infarction. PMID- 4307140 TI - Hypertension with inappropriate aldosterone stimulation. PMID- 4307142 TI - [Carpal tunnel syndrome. A follow-up study of 91 operated cases]. PMID- 4307143 TI - [Genetic basis of cell resistance to virus infections]. PMID- 4307144 TI - [Diagnostic difficulties in a case of insuloma of the pancreas with the symptoms of temporal epilepsy]. PMID- 4307145 TI - Pediatric arteriography in abdominal and extremity lesions. Clinical experience, indications, and technic. PMID- 4307148 TI - [Soft-tissue tumors, with special reference to those o hisiocytic origin]. PMID- 4307146 TI - Properties of the trypsinised red cell receptor reacting in reversible agglutination by normal sera. PMID- 4307147 TI - Pituitary control of erythropoiesis. PMID- 4307149 TI - [On cylindroma of the minor salivary glands]. PMID- 4307150 TI - Some principles of surgical and prosthodontic treatment of patients with malignant tumours of the maxilla. PMID- 4307151 TI - Multiple primary carcinomata of the colon. PMID- 4307152 TI - [Animal experimental studies on synthetic peptides with corticotropin activity. A. Comparison with 3rd international Standard for corticotropin]. PMID- 4307153 TI - [Animal experimental studies on synthetic peptides with corticotropin activity. B. Test of a depot-preparation of beta 1-23-corticotropin-23-amide-acetate]. PMID- 4307154 TI - [Comparative studies on the effect of a beta 1-23-corticotropin-23-amide and an ACTH extract in man]. PMID- 4307155 TI - [Pleural mesothelioma in silicosis]. PMID- 4307157 TI - [Trophoblastic tumor and its treatment]. PMID- 4307158 TI - [Apropos of cytologic interpretation of 2 antehypophyseal adenomas with acromegaly]. PMID- 4307156 TI - Mechanism of hormone action. Role of nucleotides in gluconeogenesis. PMID- 4307159 TI - [Scintigraphic studies in diagnosis of glomus jugulare tumors]. PMID- 4307162 TI - Criteria for distinguishing normal from subnormal adrenocortical function using the Synacthen test. PMID- 4307161 TI - Virus infections in patients with malignant disease. PMID- 4307163 TI - [Hypoglycemic insular tumors in adults. Biological and radiologic diagnosis]. PMID- 4307160 TI - Insulin antibodies. PMID- 4307164 TI - [Radiotherapy of malignant neoplasms of the maxillary sinus. (Clinico-statistical contribution)]. PMID- 4307165 TI - [Neoplasms of the facial massif with cylindromatous evolution]. PMID- 4307167 TI - [Arterial hypertension with kidney tumors in children. Influence of preoperative radiotherapy]. PMID- 4307166 TI - [Various aspects of the behavior of cesium-137]. PMID- 4307169 TI - [Surgery of congenital and acquired orificial lesions of the aorta in childhood]. PMID- 4307168 TI - [Contribution to the study of the interference of the renin-angiotensin aldosterone system during the development of chronic alcoholic hepatopathy]. PMID- 4307170 TI - [Contribution to the clinical study of a new neuroleptic: sulpiride]. PMID- 4307171 TI - [Survival in chronic myeloid leukemia following aplasia caused by Misulban]. PMID- 4307172 TI - [Mendelson's syndrome. Apropos of a case in the absence of general anesthesia or coma]. PMID- 4307174 TI - [Determination of the age of the human fetus on the basis of ossification centers of the maxilla]. PMID- 4307173 TI - [Attitude in the presence of chronic constipation]. PMID- 4307175 TI - Recent developments in the identification of human skeletal material. PMID- 4307176 TI - Quantitative determination of formaldehyde liberated with periodate oxidation. PMID- 4307177 TI - Chromosomal aberrations in two cases of inherited aplastic anemia with unusual clinical features. PMID- 4307178 TI - Cytomegalovirus mononucleosis in previously healthy individuals. Five new cases and follow-up of 13 previously published cases. PMID- 4307179 TI - Evidence for glycolysis in bovine retinal microsomes and photoreceptor outer segments. PMID- 4307180 TI - Transport phenomena associated with the deposition and disappearance of pyrophosphate granules in Tetrahymena pyriformis. PMID- 4307181 TI - The biosynthesis and degradation of nicotinamide-adenine dinucleotide during cick embryonic development. PMID- 4307183 TI - Electron spin resonance studies of ribonucleotide reduction catalyzed by the ribonucleotide eductase of Lactobacillus leichmannii. PMID- 4307182 TI - Localization of factor VII (proconvertin) in a microsomal subfraction. PMID- 4307184 TI - Dietary regulationof glycolytic enzymes. 3. Adaptive changes in rat jejunal pyruvate kinase, phosphofructokinase, fructosediphosphatase and glycerol-3 phosphate dehydrogenase. PMID- 4307185 TI - Effects of fasting, diabetes and glucocorticoids on gluconeogenic enzymes in the sheep. PMID- 4307186 TI - Regulation of the synthesis of 5-phosphoribosyl-I-pyrophosphate in intact red blood cells and in cell-free preparations. PMID- 4307188 TI - [On the method of isolating enteroviruses from water]. PMID- 4307189 TI - Foot drop. PMID- 4307187 TI - [The effect of various factors on the multiplication of Cl. perfringens]. PMID- 4307190 TI - Surgical treatment of primary liver cancer. PMID- 4307191 TI - Micropuncture study of the action of angiotensin-II on tubular sodium and water reabsorption in the rat. PMID- 4307192 TI - The effect of an expansion of extracellular fluids on net Na flux in the jejunum of rats. An experimental model for the study of the third factor. PMID- 4307193 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 31-1969. PMID- 4307194 TI - Estrogen replacement therapy. PMID- 4307195 TI - Ultrastructural localization of metabolic enzymes during the human endometrial cycle. PMID- 4307196 TI - [A case of inborn hypophosphatasia]. PMID- 4307197 TI - Tumors of the parapharyngeal space. PMID- 4307199 TI - Evaluation of the role of the feedback effect of corticosteroids in the control of pituitary ACTH release. PMID- 4307198 TI - [Acute kidney alterations following histamine shock]. PMID- 4307200 TI - Effect of angiotensin superfusion on the rate of aldosterone production by incubated rat adrenals. PMID- 4307201 TI - Isolation of rough and smooth microsomes from rat liver by means of a commerically available centrifuge. PMID- 4307202 TI - Fluorometric micro determination of citrate in tissue extracts. PMID- 4307203 TI - Use of the liquid scintillation spectrometer for determining adenosine triphosphate by the luciferase enzyme. PMID- 4307204 TI - Adenyl cyclase assay in fat cell ghosts. PMID- 4307205 TI - Use of polyethyleneimine-cellulose thin layers in assay of pyrophosphate-ATP exchange reactions. PMID- 4307206 TI - [Melatonin and adrenal steroidogenesis]. PMID- 4307207 TI - Coagenase in corneal ulcerations. PMID- 4307208 TI - Prevention of the ulcers of the alkali-burned cornea. Preliminary studies with collagenase inhibitors. PMID- 4307209 TI - Epidemiology of major respiratory diseases of the horse. PMID- 4307210 TI - A selective inactivation of dimethylallyl-transfering activity of prenyltransferase. PMID- 4307211 TI - A new pyruvate kinase isozyme in hepatomas. PMID- 4307212 TI - Flocculating antigen in the sera of haemorrhagic smallpox cases. PMID- 4307213 TI - Metabolic and electrophoretic studies of rat liver sorbitol dehydrogenase. PMID- 4307214 TI - ADP-dependent palmitoylcarnitine sensitivity of mitochondria isolated from the perfused rabbit heart. PMID- 4307215 TI - Biochemical studies on lipopolysaccharides of Salmonella R mutants. 6. Investigations on the structure of the lipid A component. PMID- 4307216 TI - Changes in the short wavelength absorption spectrum of tyrosine as a result of its participation in peptide, or similar bonds. PMID- 4307217 TI - Antibodies against degradation products of polysaccharide antigens. PMID- 4307218 TI - NAD nucleosidase activity in rabbit reticulocytes and erythrocytes. PMID- 4307219 TI - Effect of tolbutamide on the lipolytic response of adipose tissue to adrenaline and ACTH. PMID- 4307221 TI - Histochemical localization of some enzymes in the ampullae of the bull ductus deferens. PMID- 4307220 TI - Mechanism of ovarian cholesterol mobilization by luteinizing hormone. PMID- 4307222 TI - Intranuclear and intranucleolar tubular structures in Novikoff hepatoma cells. PMID- 4307224 TI - Electrical transmission mediated by an identified cholinergic neuron of Aplysia. PMID- 4307223 TI - Hemodynamic spectrum of vasopressor and vasodilator drugs. PMID- 4307226 TI - Recombination and segregation in somatic cell hybrids. PMID- 4307225 TI - Angiotensin teratogenicity in the fetal hamster. PMID- 4307227 TI - Aphasia and rapid eye movement sleep. PMID- 4307228 TI - Signal transmission along retinal rods and the origin of the electroretinographic a-wave. PMID- 4307229 TI - Attenuation of rhinovirus type 15 for humans. PMID- 4307230 TI - Protection against poxviruses. PMID- 4307231 TI - Influence of synthetic (poly I:C) and viral double-stranded ribonucleic acids on adenovirus 12 oncogenesis in hamsters. PMID- 4307232 TI - Alpha-methyl-1-adamantane-methylamine hydrochloride: inhibition of Rous and Esh sarcoma viruses in cell culture. PMID- 4307234 TI - A study correlating virus particle frequency with disease progession in a transmitted murine leukemia. PMID- 4307233 TI - Biological characteristics and viral spectrum of serially cultivated fetal rhesus monkey kidney cells. PMID- 4307235 TI - The hydrolytic activity in normal human and malignant tissue. PMID- 4307236 TI - Passive hemagglutination enhancement by periodate, low pH, and freeze-thaw treatment of aldehyde processed cells. PMID- 4307237 TI - Isolation and growth of rat cytomegalovirus in vitro. PMID- 4307238 TI - Cyclic adenylate and hypothalamic regulatory functions. PMID- 4307240 TI - Hypoproteinemia in mice after treatment with histamine-sensitizing factor from Bordetella pertussis. PMID- 4307239 TI - Refractoriness of KB cell cultures carrying Japanese B encephalitis virus to encephalomyocarditis virus infection. PMID- 4307241 TI - Exercise, stress, and blood clotting in men. PMID- 4307242 TI - [Relation between reaction to a series of bacteriophages and phenotypic characteristics of a group of Welchia perfringens]. PMID- 4307243 TI - [The comparison of contrast media used in sialographic examinations]. PMID- 4307244 TI - Hypothalamicohypophyseal portal system in experimental ovarian tumorigenesis. PMID- 4307245 TI - Somato-sensory evoked cortical potentials in subjects with peripheral nervous lesions. PMID- 4307246 TI - The electromyogram in the evaluation of nerve injuries occurring in hospitalized patients. PMID- 4307247 TI - Natural and melatonin-induced sleep in young chickens--a behavioral and electrographic study. PMID- 4307248 TI - [On the importance of the silanol group of the hydrated silica surface in the pathogenesis of silicosis (experimental study)]. PMID- 4307249 TI - Growth and sporulation of Clostridium welchii in breast and leg muscle of poultry. PMID- 4307251 TI - Comparative study of experimental herpes simplex encephalitis, rabies and Japanese encephalitis demonostrated by fluorescent antibody method. PMID- 4307252 TI - Herpes simplex encephalitis. PMID- 4307250 TI - Effect of antineoplastic agents on microsomal enzymes. PMID- 4307253 TI - Acute focal inclusion encephalitis a clinical pathological entity heretofore unrecognized in Israel (a study of 10 cases). PMID- 4307255 TI - Cerebral lesions in generalized salivary gland virus infection (cytomegalic inclusion disease). PMID- 4307254 TI - Perinatal cytomegalic inclusion encephalitis. PMID- 4307256 TI - An autopsy case of acute hemorrhagic necrotizing encephalitis diagnosed as Japanese encephalitis by means of fluorescent antibody technique. PMID- 4307257 TI - [Acute necrotising encephalitis]. PMID- 4307258 TI - [A propos of regular and radioactive lymphography in chronic lymphocytic leukemias]. PMID- 4307259 TI - [Adrenal reserve in healthy children with normal and enlarged thymus]. PMID- 4307260 TI - [Angiotensin-infusion test in the diagnosis of renovascular hypertension]. PMID- 4307261 TI - [Sleep distrubances--soporifics]. PMID- 4307262 TI - [A histochemical study of proteins, nucleic acids and nonspecific phosphomonoesterases of the skin in experimentl dermatitis]. PMID- 4307263 TI - [Surgical treatment of breast carcinoma. (analysis of 352 cases)]. PMID- 4307264 TI - Arteriography in children with abdominal mass. PMID- 4307265 TI - [Agarose preparation on a laboratory scale]. PMID- 4307266 TI - [A comparative evaluation of the resistance of several enteroviruses and sanitary indicative microorganisms to the effect of active chlorine]. PMID- 4307268 TI - Pituitary adrenocorticotrophic hormone (ACTH) induced hypoglycaemia. PMID- 4307269 TI - Effect of the median eminence of the pigeon (Columba livia domestica L.) on the regulation of adenohypophysial corticotropin secretion. PMID- 4307267 TI - [Cultivation and reproduction of herpes simplex virus in nervous system cell cultures]. PMID- 4307270 TI - A neuropharmacological analysis of hypothalamic and extrahypothalamic mechanisms concerned with the regulation of food and water intake. PMID- 4307271 TI - Chemical mechanisms in the hypothalamus mediating eating and drinking in the monkey. PMID- 4307273 TI - [Effect of sympathicus blockade and increased blood flow through the kidneys on the action of angiotensin on the kidney function in hypertensives]. PMID- 4307272 TI - Physical studies of phospholipids. XI. Ca2+ binding to monolayers of phosphatidylserine and phosphatidylinositol. PMID- 4307274 TI - [Contribution to the epidemiology of respiratory infections caused by adenoviruses type 5]. PMID- 4307275 TI - [Quantitative sensitivity of Clostridium perfringens to neomycin in relation to cultivation technic]. PMID- 4307276 TI - [Peaceful sleep in term and premature babies in the 1st months of life]. PMID- 4307277 TI - [On diencephalo-hypophyseo-adrenocortical function in various diseases]. PMID- 4307278 TI - [On a new procedure for the anatomic and functional reconstruction of the soft palate in extensive resection defects]. PMID- 4307279 TI - [The effect of strychninization of the somatosensory cortex on the evoked activity of neurons in the association area]. PMID- 4307281 TI - [Novel synthesis of l-alpha, beta-diaminopropionic acid]. PMID- 4307282 TI - [The extraction of purified preparations of glutaminase from Clostridium welchii SR-12]. PMID- 4307283 TI - [Examination of the cerebrospinal fluid in supratentorial cerebral tumors. Statistical findings and practical considerations]. PMID- 4307280 TI - [On the toxicity and fibrogenic aspects of lead silicate]. PMID- 4307284 TI - [Enzymological study of acute anicteric hepatitis in Crosti-Giannotti disease]. PMID- 4307285 TI - [Organic hypoglycemia in association with a malignant tumor and an islet cell adenoma. Determining role of blood insulin determination for the etiologic diagnosis and surgical procedure]. PMID- 4307286 TI - [Carotid body tumors and familial glomic disease]. PMID- 4307287 TI - [Cyclic AMP in the brain and its regulation]. PMID- 4307288 TI - [GABA as a neurotransmitter substance]. PMID- 4307289 TI - [Studies on neurochemistry in Japan. 1963-1968]. PMID- 4307290 TI - [Poisoning by ethylene glycol. An antidote: the citrate ion]. PMID- 4307292 TI - Inductive transformation as a basic phenomenon in the genesis of cells of the zona fasciculata and reticularis of the adrenal cortex. PMID- 4307291 TI - [Hyperglycemic coma without ketosis, with dehydration, chlorosodic and potassic deficiency, after treatment with salidiuretics, in nondiabetic patients]. PMID- 4307293 TI - [Histological and histochemical studies on the effect of vitamin A deficiency and hypervitaminosis A on the endometrium of sexually mature rats]. PMID- 4307294 TI - The use of cytostatic drugs in the treatment of trophoblastic neoplasia. PMID- 4307295 TI - Blood pressure responses to angiotensin II following aldosterone and adrenalectomy. PMID- 4307297 TI - [Experiments on the treatment of Pseudomonas corneal ulcer. 2. Comparison of the effect of various antibiotics]. PMID- 4307296 TI - Transmission between adrenergic nerves and smooth muscle in the course of Wallerian degeneration. PMID- 4307298 TI - 6. The fine structure of human photoreceptor synapses. PMID- 4307299 TI - Histochemical and morphologic changes in gastric mucosa of dogs on ulcerogenic regimen. PMID- 4307300 TI - Induction in hamsters of various carcinomas and sarcomas by in-vitro SV40 transformed homologous embryonic skin and subcutaneous tissue cells. Role of target cells in determining tumor morphology. PMID- 4307301 TI - Sucrose interference in the assay of enzymes and protein. PMID- 4307302 TI - Determination of coenzyme A and acetyl CoA in tissue extracts. PMID- 4307303 TI - Method for creating rapid cellular temperature perturbation. PMID- 4307306 TI - [Pain in amputation neuromas]. PMID- 4307304 TI - Carboxyl-terminal sequence of the glycine-arginine-rich histone from bovine lymphosarcoma, Novikoff hepatoma and fetal calf thymus. PMID- 4307305 TI - Neurological disease after partial gastrectomy. AB - Clinical and laboratory signs of neurological disease were found in 14 patients many years after partial gastrectomy. Vitamin B(12) deficiency occurred in most patients, but only those three who had signs of subacute combined degeneration of the cord and no osteomalacia responded well to treatment. PMID- 4307307 TI - Studies on lymphocytosis induced by Hemophilus pertussis. I. Observations of cell counts in media after incubation of thymus cells and lymph node cells. PMID- 4307308 TI - Studies on lymphocytosis induced by Hemophilus pertussis. II. Hematological histochemical observations in experimental animals. PMID- 4307309 TI - Studies on lymphocytosis induced by Hemophilus pertussis. 3. Clinical studies: observations of peripheral blood and cultured lymphocytes in vitro. PMID- 4307310 TI - Studies on the morphogenesis of yeast mitochondria. 1. Development of mitochondrial functions during the growth phases of Saccharomyces cerevisiae. PMID- 4307311 TI - Base sequences of small oligonucleotides. 1. Spectrophotometric determination of the structure of some adenine and guanine containing dinucleoside-monophosphates. PMID- 4307313 TI - Standard Gibbs free energy, enthalpy, and entropy changes as a function of pH and pMg for several reactions involving adenosine phosphates. PMID- 4307312 TI - Purification and properties of the L-cysteinyl ribonucleic acid synthetase of bakers' yeast. PMID- 4307314 TI - An adenosine 3',5'-monophosphate-dependent protein kinase from Escherichia coli. PMID- 4307315 TI - Nicotinic and muscarinic receptors in the cardiac sympathetic ganglia of the dog. PMID- 4307316 TI - Effects of nicotine, dimethylphenylpiperazinium and cholinergic blocking agents at adrenergic nerve endings of the rabbit pulmonary artery. PMID- 4307318 TI - Effect of alpha-methyl dopa on the reserpine-induced suppression of motor activity and the conditioned avoidance response. PMID- 4307317 TI - Effects of environmental lighting and chronic denervation on the activation of adenyl cyclase of rat pineal gland by norepinephrine and sodium fluoride. PMID- 4307319 TI - [Studies on free radicals in tumor tissue of the urinary bladder. 1. Free radicals in human normal bladder mucosa and transitional cell carcinoma of the urinary bladder analyzed with electron spin resonance (ESR)]. PMID- 4307320 TI - [Dermatologic experience with the staphylomycin preparations--staphylomycin-P and Stapolidex]. PMID- 4307321 TI - [Evaluation of risk]. PMID- 4307322 TI - [Bronchial fistulization of a lumbar Pott's abscess. Direct approach to the Pott's focus: drying of the bronchial fistula]. PMID- 4307323 TI - Plasma insulin studies in the diagnosis of insulinoma. PMID- 4307325 TI - [Acute myocarditis in the newborn infant. Its relations with fibroelastosis. Its treatment]. PMID- 4307324 TI - [Treatment of rheumatic cardiopathies]. PMID- 4307326 TI - [Surgery of congenital cardiopathies during the 1st weeks of life]. PMID- 4307327 TI - [Alcoholic hypoglycemia in adults]. PMID- 4307328 TI - [Unpleasant or painful reactions of Parkinson's disease and of the neuroleptic therapy (paresthesia, impatience, cramps, akathisia). Their improvement by alimemazine]. PMID- 4307329 TI - [Effect of thyroid and adrenal dysfunction on changes in tissue concentration of calcium and glucose]. PMID- 4307330 TI - [The role of the correction of hypoxemia in reduction of rhythm disorders accompanying acute respiratory failure. Apropos of 2 cases]. PMID- 4307331 TI - [A case of serious intolerance during treatment by phenindione: preventive measures to be taken]. PMID- 4307333 TI - [Value and indications of fibrogastroscopy. Study on 1st series of 200 cases]. PMID- 4307332 TI - [Are hydrosolubles preferable to iodized oil for hysterosalpingography]. PMID- 4307334 TI - [Auriculo-ventricular block during the acute phase of myocardial infarction. Apropos of 46 cases]. PMID- 4307335 TI - [Thyroid metastasis of a clear-cell epithelioma of the kidney]. PMID- 4307336 TI - [Choice and utilization of antibiotics in gastroenterology. Advantage of a new broad-spectrum antibiotic: etamocycline]. PMID- 4307337 TI - [Thoughts on 125 cases of complete auriculo-ventricular blocks]. PMID- 4307339 TI - Histological study of the hypophysis of the transylvanian lamprey (Eudontomyzon danfordi Regan). PMID- 4307338 TI - Sudden unexpected unexplained death in infants. A comparative clinicopathologic study. PMID- 4307340 TI - Luteoma of pregnancy: steroidogenic and morphologic considerations. PMID- 4307342 TI - Serologic study of a canine adenovirus (Toronto A26/61) infection in dogs. PMID- 4307341 TI - Reoviruses isolated from turkeys with bluecomb. PMID- 4307343 TI - Diagnosis of bluetongue in cattle by intravascular inoculation of chicken embryos and immunofluorescence. PMID- 4307344 TI - Pathologic changes in placentas of ewes inoculated with bluetongue virus. PMID- 4307345 TI - Mechanism of action of aldosterone. PMID- 4307346 TI - Inhibition by formaldehyde of energy transfer and related processes in rat liver mitochondria. II. Effects on energy-linked reactions in intact mitochondria and phosphorylating particles. PMID- 4307347 TI - Partial purification and properties of ATP:GMP phosphransferase from rat liver. PMID- 4307348 TI - RNA synthesis in exponentially growing rat hepatoma cells. I. A caution in equating pulse-labeled polyribosomal RNA with messenger RNA. PMID- 4307349 TI - An improved, reproducible method opreparing rat liver plasma cell membranes in buffered isotonic sucrose. PMID- 4307350 TI - Enzyme activities and ultrastructure of a membrane fraction from human erythrocytes. PMID- 4307351 TI - Enzymatic distinction of rat intestinal cell brush border and endoplasmic reticular membranes. PMID- 4307352 TI - Calcium binding properties of sarcoplasmic reticulum membranes. PMID- 4307353 TI - Synthesis and turnover of membrane protein and lipid in Mycoplasma laidlawii. PMID- 4307354 TI - Quantification of baroreceptor reflexes during anaesthesi in man. PMID- 4307355 TI - Amoebic colitis exacerbated by steroids. PMID- 4307356 TI - The phenomenon of differentiation in murine irus-induced leukemic cells. PMID- 4307357 TI - Host resistance and the biological analysis of avian tumor virus infections. PMID- 4307359 TI - Cholesterol esterase stimulation by luteinizing hormone in luteinized rat ovaries. PMID- 4307358 TI - Cell-bound immune reactions against tumor specific transplantation antigens. PMID- 4307360 TI - Cholesterol side-chain cleavage activity in the adrenal gland of the young rat: development and responsiveness to adrenocorticotropin hormone. PMID- 4307361 TI - Inhibition by dexamethasone of the in vivo pituitary response to corticotropin releasing factor (CRF). PMID- 4307362 TI - Release of ACTH by substances of central nervous system origin. PMID- 4307363 TI - Corticosteroid response to natural and synthetic corticotrophins in the autotransplanted sheep adrenal. PMID- 4307364 TI - Subcellular localization of androgen in the rat ventral prostate in vivo. PMID- 4307365 TI - Glycogen content in the rat testis from postnatal to adult ages. PMID- 4307366 TI - Reverisble inactivation of nicotinamide adenine dinucleotide kinase in extracts of unfertilized sea urchin eggs. PMID- 4307368 TI - [Symptoms of food poisoning caused by Cl. perfringens type A]. PMID- 4307367 TI - Fractionation of nuclei from induced hepatomas by sucrose gradient centrifugation. PMID- 4307369 TI - Miscellaneous viral vaccines. PMID- 4307370 TI - Hepatic abscess. An analysis of 86 cases. PMID- 4307371 TI - On the homeostatic regulation of cortical activation during sleep. PMID- 4307372 TI - The dream scene. PMID- 4307374 TI - A heat-stable nicotinamide adenine dinucleotidase from Pseudomonas fluorescens. PMID- 4307375 TI - Terpene compounds as drugs. VI. Acyclic mono- and sesquiterpene thiocyanates and isothiocyanates. PMID- 4307376 TI - Inverse relationship of interferon production and virus content in cell lines from Burkitt's lymphoma and acute leukemias. PMID- 4307377 TI - Noncovalent binding of a spin-labeled inhibitor to ribonuclease. AB - The stable free radical 2,2,6, 6-tetramethyl-4-hydroxypiperidin-1-oxyl monophosphate has been synthesized; it binds to ribonuclease. The selective changes in the nuclear magnetic resonance spectrum of the enzyme produced by the free radical make it possible to define qualitatively the region of the enzyme to which it binds. The radical appears to occupy a site similar to that to which inorganic phosphate binds which is close to or within the active site of the enzyme. PMID- 4307378 TI - Human growth hormone release: relation to slow-wave sleep and sleep-walking cycles. AB - Release of human growth hormone during sleep is significantly related to slow, synchronized stages of sleep and therefore would seem to be controlled by related neural mechanisms. When sleep-waking cycles are reversed by 12 hours, the release of growth hormone with sleep is reversed; thus release does not follow an inherent circadian rhythm independent of sleep. PMID- 4307379 TI - Hormonal regulation of nucleic acid and protein synthesis. PMID- 4307380 TI - Egg production and disease: adenovirus. PMID- 4307382 TI - [On the reaction of helix-agglutinins with ZAJDELA hepatoma cells with regard to the steric arragement of antibodies]. PMID- 4307381 TI - [Biochemical and clinical aspects of pyrophosphate metabolism. 1. Rateand mechanism of elimination of 32P labeled pyrophosphate from the blood plasma and its distribution within the organism]. PMID- 4307383 TI - [On the mechanism of action of pyrogenic substances on blood sugar changes]. PMID- 4307384 TI - [Malabsorption syndrome caused by a transitory disorder of isomaltose hydrolysis in atrophic infants]. PMID- 4307385 TI - [Contribution of preoperative lipiodol bronchogramm in the practice of thoracic surgery (I)]. PMID- 4307386 TI - Induction of NAD-specific glutamate dehydrogenase in Neurospora crassa by addition of glutamate to the media. PMID- 4307387 TI - Histochemical study of nephroblastoma. PMID- 4307388 TI - Ribonucleic acid depolymerizing enzyme in Entamoeba histolytica. PMID- 4307389 TI - Thron test in leprosy. PMID- 4307391 TI - [The effect of C-vitaminization on the development of experimental pneumoconiosis]. PMID- 4307392 TI - [Experimental studies of the effect of alunite dust on the respiratory organs]. PMID- 4307390 TI - [The application of crossed immunoelectrophoresis in the rapid differential diagnosis between poxvirus and varicella zona virus]. PMID- 4307393 TI - [Clinico-radiographic characteristics of pneumoconiosis in workers of refractory brick and ceramic plants of the Moscow District]. PMID- 4307394 TI - Thyroid function in a family with the Pendred syndrome. PMID- 4307395 TI - Plasma levels of testosterone in male rabbits following copulation. PMID- 4307397 TI - [Study on the renin-angiotensin-aldosterone system. Effects of sodium restriction and postural changes on plasma renin activity and fluctuation in urinary aldosterone]. PMID- 4307396 TI - Renin release from ischemic kidneys following angiotensin infusion in dogs. PMID- 4307398 TI - The ultrastructural distribution of cytochrome oxidase activity in Plasmodium Berghei and P. Gallinaceum. PMID- 4307399 TI - On the functional aspects of a preparation of an inner membrane fraction of liver mitochondria I. PMID- 4307400 TI - [On the treatment of maxillary sinusitis with terracortril gel]. PMID- 4307401 TI - [Malignant nesidioblastome revealed by jaundice]. PMID- 4307402 TI - [Recent aspects of nervous tissue in culture. 2. Use of the nervous tissue culture]. PMID- 4307403 TI - [Ultrastructural characteristics of tumor cells]. PMID- 4307404 TI - [Cytomegaly in relation to biological defects in infants]. PMID- 4307405 TI - [Evolution of RNA synthesis in Ehrlich ascitic cells in the early stages after infection with Sendai virus]. PMID- 4307406 TI - Acute nonsuppurative meningoencephalitis associated with transient amaurosis. PMID- 4307407 TI - Iatrogenesis in anesthesiology. PMID- 4307408 TI - Interaction of a spin-labeled analog of nicotinamide-adenine dinucleotide with alcohol dehydrogenase. I. Synthesis, kinetics, and electron paramagnetic resonance studies. PMID- 4307409 TI - Interaction of a spin-labeled analog of nicotinamide-adenine dinucleotide with alcohol dehydrogenase. II. Proton relaxation rate and electron paramagnetic resonance studies of binary and ternary complexes. PMID- 4307410 TI - Influence of substrates on the dissociation of rabbit muscle D-glyceraldehyde 3 phosphate dehydrogenase. PMID- 4307411 TI - Substrate binding specificity and properties of inosine monophosphate: pyrophosphate phosphoribosyltransferase (EC 2.4.2.8) from Brewers yeast. PMID- 4307412 TI - Rat liver D-beta-hydroxybutyrate dehydrogenase. 3. Inhibition by topical anesthetics. PMID- 4307413 TI - The synthesis of 25-hydroxycholecalciferol. A biologically active metabolite of vitamin D3. PMID- 4307414 TI - Serum free fatty acids, growth hormone, and insulin during trials of ACTH and synthetic subunits. PMID- 4307415 TI - Differential effects of scopolamine and chlorpromazine on REM and NREM sleep in normal male subjects. PMID- 4307416 TI - Comparison of haemodynamic effects of equipressor doses of intravenous angiotensin and noradrenaline in man. PMID- 4307417 TI - An analysis of technetium (99mTcO4-) kinetics: the effect of perchlorate and iodide pretreatment. PMID- 4307418 TI - Skeletal changes following irradiation of childhood tumors. PMID- 4307420 TI - Overlap and the errors of plaque counting. I. The overlap biases of observed counts and their correction. PMID- 4307419 TI - Empirical selection of antibiotics for hand infections. PMID- 4307421 TI - Effect of Sabin poliovirus vaccine on incidence of poliomyelitis in Italy. PMID- 4307422 TI - Electron spin resonance signals in injured nerve. AB - Under certain conditions nerves (such as the frog sciatic) exhibit electron spin resonance signals with several unusual properties: (i) variable g value and linewidth, (ii) anisotropic g tensor, and (iii) g value dependence on temperature. Such a signal must be due to a small ferromagnetic crystal formed when the nerve is subjected to pressure, such as that due to mechanical injury. PMID- 4307423 TI - [Isolation of native ribonucleoprotein from Sendai virus]. PMID- 4307424 TI - [Mixed tumor in maxillofacial region]. PMID- 4307425 TI - Acute respiratory illness in nursery school children: a longitudinal study of the occurrence of illness and respiratory viruses. PMID- 4307427 TI - The accumulation and elimination of crude and clarified poliovirus suxpensions by shellfish. PMID- 4307426 TI - Rhinovirus infections of children in hospital; isolation of three possibly new rhinovirus serotypes. PMID- 4307428 TI - Glomus tumor of the stomach. Report of a case and review of the literature. PMID- 4307430 TI - Surgical resection of intrahepatic bile duct cancer. PMID- 4307431 TI - Malignant abdominal neoplasms in childhood. PMID- 4307429 TI - Roentgen findings in extramedullary hematopoiesis. PMID- 4307432 TI - Insulin stimulatory tests in a patient with islet cell adenoma. PMID- 4307433 TI - Ultrastructural injury of arterial endothelium. II. Effects of vasoactive amines. PMID- 4307435 TI - Pulmonary adenomatosis and peripheral adenocarcinoma of the lung. An ultrastructural demonstration of common morphologic features. PMID- 4307434 TI - Ultrastructural injury of arterial endothelium. 3. Effects of enzymes and surfactants. PMID- 4307436 TI - Breast cancer in a man treated with diethylstilbestrol. PMID- 4307437 TI - Electron spin resonance of Cu(II) in copper-hemoglobin complexes. PMID- 4307438 TI - Poly-(L)-malic acid; a new protease inhibitor from Penicillium cyclopium. PMID- 4307439 TI - Adenyl cyclase and hormone action. 3. Calcium requirement for ACTH stimulation of adenyl cyclase. PMID- 4307440 TI - Demonstration of adenyl cyclase activity in canine cardiac sarcoplasmic reticulum. PMID- 4307441 TI - Comparative effects on RNA polymerase of the whole GAR histone and its peptides containing clusters of basic amino acids. PMID- 4307442 TI - Adenyl cyclase: relationship to stimulated DNA synthesis in parotid glands. PMID- 4307443 TI - Animal cell cultures as a source of hormones. PMID- 4307444 TI - The propagation and cytomorphological effects of bovine parainfluenza type 3 virus in organ cultures of bovine fetal tissues. PMID- 4307445 TI - Effect of triton WR-1339 on rous virus-induced tumors in chickens. PMID- 4307446 TI - An electron microscopic comparison of three strains of bovine parainfluenza-3 virus. PMID- 4307447 TI - Low birthweight and postnatal physical development. PMID- 4307448 TI - The "internal sphincter": is it under sympathetic control? PMID- 4307449 TI - Independence of the effects of epinephrine, glucagon, and adrenocorticotropin on glucose utilization from those on lipolysis in isolated rat adipose cells. PMID- 4307450 TI - Biological mechanisms involved in the formation of deoxy sugars. V. Isolation and crystallization of thymidine diphosphate-D-glucose oxidoreductase from Escherichia coli B. PMID- 4307451 TI - Tryptophan oxygenase of Pseudomonas acidovorans. Purification, composition, and subunit structure. PMID- 4307453 TI - Adenyl cyclase in fat cells. II. Hormone receptors. PMID- 4307452 TI - Adenyl cyclase in fat cells. 1. Properties and the effects of adrenocorticotropin and fluoride. PMID- 4307454 TI - Response of trypsin-treated brown and white fat cells to hormones. Preferential inhibition of insulin action. PMID- 4307455 TI - Beta oxidation in glyoxysomes from castor bean endosperm. PMID- 4307456 TI - Mammalian alpha-keto acid dehydrogenase complexes. V. Resolution and reconstitution studies of the pig heart pyruvate dehydrogenase complex. PMID- 4307457 TI - Stimulation and suppression of aldosterone in plasma of normal man and in primary aldosteronism. AB - The effect of stimulating and suppressive influences on plasma aldosterone in normal man and in patients with primary aldosteronism were studied using a sensitive double-isotope derivative assay for aldosterone. In normal sitting subjects, values were 9.2+/-0.9 (SE) mmug/100 ml and in subjects supine for 1 hr plasma aldosterone was 5.2+/-0.4 (SE) mmug/100 ml. Adrenocorticotropic hormone (ACTH), 0.5 U/hr, produced a rise of 46.8+/-22 (SE) mmug which was similar to the 1-hr effect of an infusion of a synthetic ACTH (beta(1-24), Cortrosyn). Angiotensin II in pressor amounts also increased plasma aldosterone 21.5+/-2.9 (SE) without change in plasma cortisol, whereas a subpressor dose ([unk]) had minimal effect.Fludrocortisone, 1.2 mg/day for 3 days, suppressed plasma aldosterone levels to 1.8+/-0.7 (SE) mmug/100 ml in five normal sitting subjects (P < 0.01); however, dexamethasone, 2 mg/day for 1-2 days, did not lower aldosterone concentration in plasma. In six patients with primary aldosteronism, plasma aldosterone on a normal sodium diet was 39.1+/-4.4 (SE) which differed significantly from normal sitting or supine subjects (P < 0.001). In contrast to the normal subjects, neither a pressor infusion of angiotensin II for 1 hr, nor fludrocortisone, 1.2 mg/day for 3 days, impressively altered plasma aldosterone levels. This approach appears to be useful for the study of the acute physiology and control mechanisms of aldosterone production in normal and hypertensive man. PMID- 4307458 TI - The role of the liver in the metabolism of vitamin D. AB - The metabolism of vitamin D(3) has been studied after intravenous injection of 10 IU of [1,2-(3)H]-vitamin D(3) to vitamin D-deficient rats. The disappearance of the radioactivity from the plasma follows a very peculiar pattern characterized by an early rapid disappearance followed by a rebound of radioactivity before assuming still a third rather slow disappearance rate. The "rebound" phenomenon is concomitant with a rapid release of the radioactivity from the liver and is accounted for by the appearance of 25-hydroxycholecalciferol and other metabolites in the blood. It is postulated that the liver is the major site of transformation of vitamin D(3) into 25-hydroxycholecalciferol. PMID- 4307459 TI - Afferent pathways of stressful stimuli: corticotropin release after partial deafferentation of the medial basal hypothalamus. PMID- 4307461 TI - The renin-angiotensin system in a marsupial (Trichosurus vulpecula). PMID- 4307460 TI - Competitive binding of free and conjugated oestrogens to plasma proteins. PMID- 4307462 TI - Bilateral testicular tumors in untreated congenital adrenocortical hyperplasia. PMID- 4307463 TI - A serological survey in dogs for antibody to human respiratory viruses. PMID- 4307464 TI - Cell-mediated demyelination of peripheral nerve in tissue culture. PMID- 4307465 TI - Mitochondrial cavitation and hypertrophy in rat adrenal cortex due to aminoglutethimide. PMID- 4307466 TI - The renin-angiotensin system in curable hypertension. PMID- 4307468 TI - Paradoxical sleep. PMID- 4307467 TI - Urologic surgery. PMID- 4307469 TI - Breast cancer. PMID- 4307470 TI - [Biosynthesis of isoprenoids--enzyme reaction in carbon chain prolongation due to C5 unit condensation]. PMID- 4307471 TI - Histochemical properties of regenerating mucous membrane in the rat stomach. PMID- 4307472 TI - Neuroglia electrically coupled to neurons. AB - Applied electric current is transmitted between mammalian glial cells grown in tissue culture. A similar electrical coupling exists between certain neurons as well as between neuroglia and neurons. Although this phenomenon may be a peculiarity of mammalian neural cells maintained in culture, it may, on the other hand, represent a phenomenon with greater neurophysiological significance, a process whereby neurons can become silent. PMID- 4307473 TI - Viomycin. PMID- 4307474 TI - The occurrence of precipitating antibodies to bovine adenovirus in sera of farm animals and man in Iran. PMID- 4307475 TI - Apert's anomaly--a transition. PMID- 4307476 TI - Abortion complicated by Clostridium welchii infection and acute renal failure. PMID- 4307477 TI - Bronchiolo-alveolar cell carcinoma of the lung. PMID- 4307478 TI - Effect of conjugated oestrogen upon gonadotrophin excretion patterns in fetile women. PMID- 4307479 TI - Adrenocorticotrophic potency of long-acting corticotrophin preparations during long-term treatment of neurological patients. PMID- 4307482 TI - [On the danger of misdiagnosis of tumor patients in complications following radiotherapy]. PMID- 4307481 TI - A comparison of two methods of determining DPNH-methemoglobin reductase. PMID- 4307480 TI - Electrophysiological studies on peripheral nervous function in multiple sclerosis. PMID- 4307483 TI - [Infectious mononucleosis virus discovered]. PMID- 4307485 TI - [Therapy of anxiety, mental anguish and sleeplessness]. PMID- 4307486 TI - [Diagnosis and therapy of the isolated, unilateral dysfunction of the vestibular nerve]. PMID- 4307487 TI - [Study of the target points of clopamide (Brinaldix) and furosemide (Lasix) in antidiuresis induced by antiotensin infusion]. PMID- 4307484 TI - [Cytohistological data on the lesional and immunological aspects of amorphous silica and of BCG. (Experimental study on the draining lymph-node in guinea pigs)]. PMID- 4307488 TI - [Hemodynamic aspects of the coronary circulation. II. Effect of angiotensin]. PMID- 4307489 TI - [Clinical findings and laboratory diagnosis in Cushing's syndrome]. PMID- 4307491 TI - ["Acquired" primary agammaglobulinemia in adults with Bence Jones proteinuria and hepatic granulomatosis]. PMID- 4307490 TI - [Reactions of the synovial membrane in chronic osteolytic arthropathies]. PMID- 4307492 TI - [Esophageal and gastric ulcer during diaphragmatic lesions. (hernias and eventrations)]. PMID- 4307493 TI - [Endoscopic aspect of hepatic distomatosis]. PMID- 4307494 TI - [A further case of congenital dilatation of intrahepatic bile ducts (Caroli's diseases)]. PMID- 4307495 TI - [Lipoatrophic diabetes. Clinical and biological study of an atypical case]. PMID- 4307496 TI - [Etiology and nosology of calcified aortic stenosis]. PMID- 4307497 TI - [The use of high-dose cyclophosphamide in the treatment of human solid tumors]. PMID- 4307500 TI - [The Bonapartes and homeopathy]. PMID- 4307498 TI - [Operated abscess of pseudo-aneurysmal myocardium and mitral insufficiency]. PMID- 4307499 TI - [The role of rectocolonic polyposis during intestinal bilharziasis]. PMID- 4307501 TI - [Bichat, Laennec--and their times]. PMID- 4307502 TI - [Immortal Bichat]. PMID- 4307503 TI - [Attempt on morphological classification of facial asymmetries]. PMID- 4307505 TI - [Indications and results of the surgical treatment of Fallot's tetralogy]. PMID- 4307504 TI - [Apropos of a case of surgical chyluria. Factors of decompensation. Surgical indications]. PMID- 4307506 TI - [Major hepatectomy for injuries of the liver. Its biologic consequences]. PMID- 4307508 TI - [The effect of prophylactic whooping-cough vaccination. An attempt at an evaluation based on experiences in Denmark]. PMID- 4307507 TI - [Congenital varicella encephalomyelitis in a surviving newborn infant]. PMID- 4307509 TI - [Brain scanning with radioactive isotopes]. PMID- 4307510 TI - [Infection of the concha auriculae by Molluscum contagiosum]. PMID- 4307512 TI - [On group infection with angina of adenoviral etiology]. PMID- 4307511 TI - [On the morphology of fibroma of the base of the skull]. PMID- 4307513 TI - [A modified indirect hemagglutination reaction for detection of antibodies to smallpox vaccine virus]. PMID- 4307514 TI - [Selected virus diseases of the horse]. PMID- 4307515 TI - [Intragenital and extragenital double carcinoma (an autopsy statistical study)]. PMID- 4307516 TI - [Isolation and fluorescence serological study of parainfluenza-3 viruses from vaginal and nasal swabs in cattle]. PMID- 4307517 TI - [Demonstration of alpha toxin of Clostridium welchii using test discs]. PMID- 4307519 TI - [Utilization of amino acids by Bordetella]. PMID- 4307518 TI - [Antigenic and immunogenic properties of the purified collagenase of Cl. histolyticum]. PMID- 4307521 TI - Iodide goiter and the pharmacologic effects of excess iodide. PMID- 4307520 TI - Preparation and testing of duck embryo cell culture rubella vaccine. PMID- 4307522 TI - Zollinger-Ellison syndrome. Clinical and histopathologic manifestations. PMID- 4307523 TI - Granular cell myoblastoma of larynx with papillary adenocarcinoma of thyroid. PMID- 4307524 TI - Laryngeal injection of teflon paste. Report of a case with postmortem study of the larynx. PMID- 4307525 TI - Surgical resection for pulmonary metastases in children. PMID- 4307526 TI - Gas gangrene. Diagnostic problems and the use of the fluorescent-antibody technique for the study of Clostridium perfringens infections. PMID- 4307527 TI - Hormone control of connective tissue. PMID- 4307528 TI - Chemodectoma (non-chromaffin paraganglioma) of the face. PMID- 4307529 TI - The renin-angiotensin system and its relation with the electrolyte balance in experimental hypertension. PMID- 4307530 TI - Incorporation of C14-lysine in the cell fractions of haemocytoblastosis-changed liver of turkey-poults treated with the leucosis strains MC-29 and MC-31. PMID- 4307532 TI - Production of acid mucopolysaccharides in mammalian fibroblast tissue cultures transformed by Rous sarcoma virus. PMID- 4307531 TI - The comparative effects of estrogens on amylase levels of cervical mucus. PMID- 4307533 TI - Use of the nucleic acid hybridization method for the demonstration of DNA homologous to Rous virus RNA in RSV-transformed mammalian cells. PMID- 4307534 TI - [The so-called gustatory sweating]. PMID- 4307535 TI - [Neurohistological changes in endocrine diseases]. PMID- 4307536 TI - Neuromuscular transmission in the longitudinal layer of somatic muscle in the earthworm. PMID- 4307537 TI - Gas chromatographic detection of in vitro and in vivo activities of certain canine viruses. PMID- 4307539 TI - Electrophysiological localization of ulnar nerve lesions. PMID- 4307538 TI - Electrophysiological and histological observations on peripheral nerves in acrylamide poisoning in man. PMID- 4307540 TI - Transient neurological distrubances in disseminated sclerosis: a case report. PMID- 4307541 TI - Hypopituitarism with paranoid psychosis: a description of two cases. PMID- 4307542 TI - Experimental virus-induced hydrocephalus. Relation to pathogenesis of the Arnold Chiari malformation. PMID- 4307543 TI - Metastasizing neuroectodermal tumors of the central nervous system. PMID- 4307545 TI - [Importance of the immunologic tests for the dosage of HCG in the diagnosis of trophoblastic tumors and in the control of the therapeutic response]. PMID- 4307544 TI - [Progress in the diagnosis and therapy of trophoblastic tumors]. PMID- 4307546 TI - [Value of vaginal cytology in the diagnosis of trophoblastic tumors]. PMID- 4307547 TI - [Hepatotoxic effects of beverage alcohol during the administration of fat diet in the rat]. PMID- 4307548 TI - [Rifampicin: a bacteriostatic and bactericidal agent]. PMID- 4307549 TI - [Recent aspects of the nervous tissue in culture. I. Current methods of culture]. PMID- 4307550 TI - [Spontaneous hypoglycemias in adults]. PMID- 4307551 TI - [Some new data on the biochemistry of insulin]. PMID- 4307553 TI - [The causes of diagnostic errors in venous disorders of the limbs vascular state of which does not constitute the main disease. A series of 477 patients]. PMID- 4307552 TI - [Medical treatment of heart failure in infants and young children]. PMID- 4307554 TI - [Comparative study of BSP excretion in young and elderly subjects]. PMID- 4307556 TI - Chronic murine hepatosplenic schistosomiasis mansoni: relative irreversibility after treatment. PMID- 4307555 TI - [Kaliopenia and electrolytic disorders revealing villous tumor of rectum]. PMID- 4307557 TI - Intestinal parasitic infections in the inhabitants of Easter Island. PMID- 4307558 TI - Low temperature strains of Entamoeba histolytica. PMID- 4307559 TI - Activity changes of phosphoprotein phosphatase, acid and alkaline phosphomonoesterases and proteinase during oogenesis and embryogenesis in the teleostean fish, Oryzias latipes. PMID- 4307560 TI - [Histochemical research on smooth muscle fibrocells of the chick embryo amnion]. PMID- 4307561 TI - Isolation of adenoviruses from cattle with conjunctivitis and kerato conjunctivitis. PMID- 4307562 TI - The urinary excretion of inorganic pyrophosphate in hyperparathyroidism, hyperthyroidism, Paget's disease and other disorders of bone metabolism. PMID- 4307563 TI - [Phosphoesterases of actinomycetales]. PMID- 4307564 TI - Immunization with inactivated poliovirus vaccine and attenuated type 3 poliovirus. II. Parallel vaccinations and cross-wise revaccination in school children with the Sabin and WM3 attenuated strains. PMID- 4307565 TI - Extensive intravascular spread of malignant hepatoma. PMID- 4307566 TI - Herpes virus infections of non-human primates: a review. PMID- 4307567 TI - Long survival in a male with 18-trisomy syndrome and Wilms' tumor. PMID- 4307568 TI - Red cell metabolism in the newborn infant. V. Glycolytic intermediates and glycolytic enzymes. PMID- 4307570 TI - [Syn-polydactyly in cattle]. PMID- 4307569 TI - [Renin and arterial hypertension]. PMID- 4307571 TI - [Demostration of infectious bovine thinotracheitis (IBR) and infectious pustulous vulvovaginitis (IPV) virus, clinical features and pathology in 2 outbreaks of a vesicular epidemic]. PMID- 4307572 TI - [Pseudomonas aeruginosa--a bacteriological ghost]. PMID- 4307573 TI - [On the epidemiologic characteristics of adenovirus infections with a diarrhea syndrome]. PMID- 4307574 TI - [Protective antigens of the pertussis microbe isolated by various methods]. PMID- 4307575 TI - [The experimental basis of the aerosol method of disinfections in viral infections. I. A method of quantitative determination of the virus on the surfaces treated with aerosol]. PMID- 4307576 TI - [Some peculiarities of pertussis epidemiology in current conditions]. PMID- 4307578 TI - Skeletal maturation of Danish school children in relation to height, sexual development, and social conditions. PMID- 4307577 TI - [Pressure-flow intensity relations of the hepatic blood supply]. PMID- 4307579 TI - Neutralization of murine typhus toxin by serum of normal human beings and monkeys. PMID- 4307580 TI - Experimental exposure of calves to a bovine rhinovirus. PMID- 4307581 TI - Carotid body and aortic body tumors in a dog--a case report. PMID- 4307582 TI - Types of fat cells and histochemistry of some oxidative enzymes in the interscapular adipose tissue of foetal, young and adult guinea pigs. PMID- 4307584 TI - The occurrence and assay of renin in human urine. PMID- 4307583 TI - The biological actions of 1,10-phenanthroline and 2,2'-bipyridine hydrochlorides, quaternary salts and metal chelates and related compounds. 1. Bacteriostatic action on selected gram-positive, gram-negative and acid-fast bacteria. PMID- 4307585 TI - The redox states of respiratory-chain components in rat-liver mitochondria. II. The "crossover" on the transition from state 3 to state 4. PMID- 4307586 TI - Compound 3 kinetics and chemiluminescence in oscillatory oxidation reactions catalyzed by horseradish peroxidase. PMID- 4307587 TI - Photosynthesis by isolated chloroplasts. IV. Regulation by factors from leaf cells. PMID- 4307588 TI - Studies on the chelate structure of the high-potential iron protein of Chromatium. PMID- 4307589 TI - Some properties of amino acid-acceptor RNA isolated from avian tumour virus BAI strain A (avian myeloblastosis). PMID- 4307590 TI - [Induction of interferon synthesis by double-stranded RNA. I. Application to the study of the multiplication cycle of Mengo virus]. PMID- 4307591 TI - Studies with ubiquinone-depleted submitochondrial particles. Essentiality of ubiquinone for the interaction of succinate dehydrogenase, NADH dehydrogenase, and cytochrome b. PMID- 4307592 TI - An improved method for isolation and identification of hydroxylated testosterone metabolites as trimethylsilyl ethers from biological material. PMID- 4307593 TI - The reduction of flavins by borohydride: 3,4-dihydroflavin. Struction, absorption and luminescence. PMID- 4307594 TI - Biosynthesis of 18-hydroxytestosterone in the human foetal liver. PMID- 4307595 TI - [Bronchiolo-alveolar carcinoma. Considerations on a case]. PMID- 4307596 TI - [Radiographic observations of the development of experimental silicosis in albino rats]. PMID- 4307597 TI - [On the possibility of intravital dissemination of Cl. perfringens in the organs and tissues of slaughter animals]. PMID- 4307598 TI - [On the problem of the possible paths of contamination of sausage items by Cl. perfringens]. PMID- 4307599 TI - [Occupational pathology of the upper limbs in computer center operators]. PMID- 4307600 TI - [On the problem of the degeneration and regeneration of peripheral nerves in experimental exposure to vibration]. PMID- 4307601 TI - The enzymic hydrolysis of phosphatidyl inositol by guinea pig brain: Sub-cellular distribution and hydrolysis products. PMID- 4307602 TI - Acetylcholine as a transmitter in the cat auditory system. PMID- 4307603 TI - [Epidemics of acute diseases of the respiratory system due to adenovirus 7 in premature infants]. PMID- 4307604 TI - [Current trends in the therapy of thyroid tumors in children]. PMID- 4307606 TI - Endocytosis of thyroglobulin and the release of thyroid hormone. PMID- 4307605 TI - [On the use of certain new antibiotics in the therapy of neonatal infections due to gram-negative bacilli. I. Clinical observations]. PMID- 4307607 TI - Sulfhydryl groups in radiation damage. PMID- 4307608 TI - Effect of dietary 2-acetylaminofluorene on rat liver enzymes involved in the anabolism and catabolism of nucleic acid precursors. PMID- 4307609 TI - Energy transfer and radioprotection in biological systems. PMID- 4307611 TI - Chemodectoma in relation to the aortic arch (aortic body tumour). A clinical report. PMID- 4307610 TI - High-dosage short-term corticotrophin therapy in acute asthma. PMID- 4307612 TI - Trial of a new anti-myxovirus compound. PMID- 4307613 TI - [Agar culture of kidney cells of green African marmosets and the cytopathic effect]. PMID- 4307614 TI - [Species specific, heterogenic (Forssman) and group antigens A, B, and N in the capsid of Sendai virus]. PMID- 4307615 TI - [A comparative study of the plaque-forming properties of human and simian para influenza viruses]. PMID- 4307616 TI - Effect of ACTH and hypophysectomy on the interrenal tissue in the common frog, Rana temporaria. PMID- 4307617 TI - The ACTH cells in the adenohypophysis of the Mexican cave fish Anoptichthys jordani, as identified by metopirone (SU 4885) treatment. PMID- 4307618 TI - Adrenergic nerves in the corpora cavernosa penis of some mammals. PMID- 4307619 TI - Salivary gland scinti-scanning with technetium 99m pertechnetate. PMID- 4307620 TI - [The use of chick embryos for study of the toxicity of pertussis microbes]. PMID- 4307621 TI - [Food toxinfection caused by Cl. perfrigens]. PMID- 4307623 TI - [Purification of Cl. perfringens anatoxin by the method of electrophoretic convection]. PMID- 4307622 TI - [Activation of the sigma-toxin of Cl. perfringens type D by the proteinases of types A and D]. PMID- 4307624 TI - [The chemical composition of the whole cell, cell wall and protoplasm of pertussis and parapertussis microbes]. PMID- 4307626 TI - [Diagnosis and treatment of epilepsy]. PMID- 4307625 TI - [The encephalitogenic activity of pertussis bacteria]. PMID- 4307628 TI - Initial high dose irradiation for metastases causing spinal cord compression in children. PMID- 4307627 TI - Movements of ventricular fluid levels due to cerebrospinal fluid formation. PMID- 4307629 TI - Adrenergic mechanisms. PMID- 4307631 TI - [Study of thermosensitive mutants of vesicular stomatitis virus (VSV). Classification of some mutants on a functional basis]. PMID- 4307630 TI - Comparative structural properties of honeybee and rabbit alpha-glycerophosphate dehydrogenases. PMID- 4307632 TI - The occurrence of a soluble glucose 6-phosphatase in cotyledon tissue of Phaseolus vulgaris during germination. PMID- 4307633 TI - Mammalian dihydroorotate--ubiquinone reducatse complex. II. Correlation with cytochrome oxidase, mode of linkage with the cytochrome chain, and general properties. PMID- 4307634 TI - [The endocrinology of puberty and adolescence. Adrenal glands]. PMID- 4307635 TI - Effects of x-irradiation of the DNA and ribonuclease levels of guinea-pig (Cavia porcellus) small intestine. PMID- 4307637 TI - Isozymic structure and pyruvate inhibition of lactate dehydrogenase of ventricle, pectoralis muscle and cerebrum, and total LDH activity of cerebrum during morphogenesis of the house sparrow, Passer domesticus. PMID- 4307636 TI - Electrophysiological investigations of the pigeon iris neuromuscular junctions. PMID- 4307638 TI - Acrasin, Acrasinase, and the sensitivity to acrasin in Dictyostelium discoideum. PMID- 4307639 TI - Inhibition of insulin secretion by aryl-substituted secondary aminoethanols. PMID- 4307640 TI - [Secretion of ACTH and content of vasopressin in hypothalamus in guinea pigs]. PMID- 4307641 TI - Fine needle aspiration biopsy of the liver in healthy adults. Activity of enzymes of glycogen utilization and glucose production. PMID- 4307642 TI - Quantitative estimation of lactate dehydrogenase isoenzymes in serum. I. Review of methods and distribution in human tissues. PMID- 4307643 TI - [On polytopic diseases of the peripheral nervous system in lymphocytic meningitis]. PMID- 4307644 TI - [Enzyme histochemical studies on the villous capillaries of the human placenta in 3 months of pregnancy]. PMID- 4307645 TI - [Experience with telegamma therapy of carcinomas of the epipharynx and the paranasal sinuses]. PMID- 4307647 TI - Metyrapone and pyrogen tests in hyperadrenocorticism: evaluation of blood corticotropin levels. PMID- 4307646 TI - The effect of oestradiol and progesterone on the activity of enzymes in the endometrium and caruncles of the ovariectomized ewe. PMID- 4307648 TI - Inhibition of the response to pituitary adrenocorticotrophic hormone in the hypophysectomized rat by circulatory corticosterone. PMID- 4307649 TI - Premature parturition after infusion of corticotrophin or cortisol into foetal lambs. PMID- 4307650 TI - Step-wise resistance to polymyxin and other agents by Pseudomonas aeruginosa. PMID- 4307651 TI - Effect of norepinephrine on 32P incorporation into individual phosphatides in slices from different areas of the guinea pig brain. PMID- 4307652 TI - A chemical method for the determination of acetylcholine: its application in a study of presynaptic release and a choline acetyltransferase assay. PMID- 4307653 TI - Fractionation of olfactory tissue homogenates. Isolation of a concentrated plasma membrane fraction. PMID- 4307654 TI - Purine and pyrimidine nucleotides in the brain of normal and convulsant rats. PMID- 4307655 TI - The effect of portacaval transposition and renal artery stenosis on the rejection of renal allografts in dogs. PMID- 4307656 TI - Sodium colistimethate (Coly-mycin). PMID- 4307657 TI - Feedback suppression of 'non-stress' pituitary-adrenal function in rats with forebrain removed. PMID- 4307658 TI - [Adenosine-3',5'-monophosphate as a messenger molecule in hormone action]. PMID- 4307660 TI - [Therapy of climacteric disorders with Menrium]. PMID- 4307659 TI - Effect of angiotensin on vascular smooth muscles. PMID- 4307662 TI - [Collagen. I. Natural condition, chemistry, physics, metabolism]. PMID- 4307661 TI - [Problem of primary vascular tumors of the lung]. PMID- 4307663 TI - [Histological and histochemical studies on the rat liver following local and whole body irradiation]. PMID- 4307664 TI - [Essay on symptoms in sialography]. PMID- 4307665 TI - Carbon-14 labeled vasoactive peptides available. PMID- 4307667 TI - Changes of drug resistance of coliform fecal microflora in pigs after total-body x-irradiation. PMID- 4307666 TI - [On the therapy of advanced malignant tumors]. PMID- 4307668 TI - Immunoassays in the diagnoses of endocrine disorders. PMID- 4307669 TI - Changes in enzyme activity and electrolite content in the myocardium in experimental myocardial hypertrophy and insufficiency. PMID- 4307670 TI - Investigations on the enzymes and toxins of staphylococci. Studies on nuclease. PMID- 4307671 TI - Investigation on the enzymes and toxins of staphyloccocci. Activity of phosphatase on sugar phosphates, nucleotides and other esters. PMID- 4307672 TI - Alteration in virulence in strains of Cryptococcus neoformans resistant to amphotericin B and polymyxin B. PMID- 4307673 TI - Reinvestigation of the cause of the increased velocity of reaction between renin and angiotensinogen in plasma from nephrectomised rats. PMID- 4307674 TI - The adrenal weight of mice with spontaneous adrenocortical lipid depletion. A comparison with untreated, ACTH- and dexamethasone-treated C57B1 mice. PMID- 4307675 TI - Histometric studies on the adrenal cortex of mice with spontaneous adrenocortical lipid depletion. A comparison with dexamethasone- and ACTH-treated C57B1 mice. PMID- 4307676 TI - Ocular involvement in neonatal herpes simplex virus infection. PMID- 4307677 TI - Unilateral corneal anesthesia in oculoauriculovertebral dysplasia. PMID- 4307678 TI - Optics and visual physiology. PMID- 4307679 TI - Relationship between the active sites of 2',3'-cyclic phosphodiesterase with 3' nucleotidase activity purified from Vibrio alginolyticus. PMID- 4307680 TI - Substrates for cytochemical demonstration of enzyme activity. IV. Kinetics of the hydrolysis of thymidine-5'(5-bromo-4-chloroindol-3-YL) phosphate by snake venom phosphodiesterase. PMID- 4307682 TI - Collagenase action on the synthetic tripeptide polymers, (gly-pro-ala)n and (gly ala-pro)n. PMID- 4307681 TI - 5 Beta-cholestane-3 alpha,7 alpha,12 alpha,26-tetrol:NAD+ oxidoreductase and 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol-26-al:NAD+ oxidoreductase in rat liver. PMID- 4307683 TI - Ineffectiveness of viomycin-resistant mutants of Rhizobium meliloti. PMID- 4307684 TI - Experimental production of diarrhea in rabbits with Clostridium perfringens. PMID- 4307685 TI - The detection of various bacteria indicative of water pollution by a presence absence (P-A) procedure. PMID- 4307686 TI - REM deprivation and hyperactivity in children. PMID- 4307687 TI - [Composition of phospholipids and their fatty acid content of rabbit erythrocytes and ghosts]. PMID- 4307688 TI - Pyruvate dehydrogenase, substrate specificity and product inhibition. PMID- 4307689 TI - Ethanol blood levels following acute i.v. administration in mice. PMID- 4307690 TI - Localization of acetylcholinesterase activity in myotendinous and myomyous junctions of the striated skeletal muscles of the rat. PMID- 4307691 TI - [Data on a study of the paramagnetic properties of various types of industrial dust and tissues of dust-loaded animals (preliminary report)]. PMID- 4307692 TI - [Experience in the sanation of working conditions in the production of lead silicate]. PMID- 4307693 TI - [On disorder of enzyme metabolism in liver and kidney cells in acute carbon tetrachloride poisoning]. PMID- 4307694 TI - [On the problem of the effect of ammonium perchlorate (PCA) on certain indices of development of the offspring of albino rats]. PMID- 4307695 TI - [Cirrhotic adenocarcinoma of the stomach as a characteristic of dog's plastic linitis, determining splenic metastases]. PMID- 4307696 TI - Effects of diphenylaminoethanol and lidocaine on central inhibition. PMID- 4307698 TI - The effect of 6-azauridine on the peripheral nervous system. II. The action on neuromuscular transmission and on striated muscle. PMID- 4307697 TI - The effects of 6-azauridine on the peripheral nervous system. I. The action on ganglionic transmission. PMID- 4307699 TI - Pharmacological studies on inhibition in the cuneate nucleus of the cat. PMID- 4307700 TI - Effect of adenosine 3',5'-monophosphate on production of glucose and ammonia by renal cortex. AB - In studies employing rat renal cortical slices, the addition of adenosine 3',5' monophosphate (cyclic AMP) to the incubation medium caused an increase in production of glucose from glutamine, glutamate, alpha-ketoglutarate, fumarate, malate, and oxalacetate, but not from glycerol and fructose. These observations suggest that cyclic AMP accelerates a rate-limiting gluconeogenic reaction between oxalacetate and the triose phosphates. The addition to the medium of parathyroid hormone, which is known to increase renal cortical cyclic AMP, also stimulated glucose production from glutamine. When renal cortical slices were incubated in the presence of glutamine, the addition of cyclic AMP caused a fall in tissue glutamate concentration and a rise in ammonia production, as well as an increase in gluconeogenesis. These changes are similar to those observed in renal cortex of rats with induced metabolic acidosis. The present observations are consistent with a previously advanced hypothesis that cortical gluconeogenesis, ammonia production, and glutamate concentration may be interdependent. PMID- 4307701 TI - Studies on the role of angiotensin in experimental renovascular hypertension: an immunologic approach. AB - The role of angiotensin in three forms of experimental hypertension was assessed in rats. First, the acute blood pressure response to injected angiotensin amide and angiotensin acid was determined. Rats made hypertensive with deoxycorticosterone and saline showed exaggerated responses; rats made hypertensive by clipping one renal artery showed depressed responses; and rats made hypertensive by clipping one renal artery and contralateral nephrectomy showed normal responsivity to angiotensin amide but depressed responsivity to angiotensin acid. These findings suggested that different mechanisms may be involved in the three types of hypertension studied. To assess the role of angiotensin in these hypertensive rats the blood pressure response, the presence of antibodies determined by radioimmune techniques, and the degree of refractoriness to injected angiotensin after immunization with angiotensin were studied. None of six rats made hypertensive by deoxycorticosterone and saline, and none of five mock immunized rats with renal hypertension of both types had a fall in blood pressure. By contrast, of the 20 rats with both types of renal hypertension in which antibody determinations were made, 11 had developed a significant antibody titer, of which seven showed a significant reduction in blood pressure at the time of antibody determination, and three of the remaining four had a significant blood pressure reduction earlier in their course. None of the nine renal hypertensive rats without demonstrable antibodies had a reduced blood pressure at the time of antibody determination, and only one had an earlier reduction in blood pressure. The renal hypertensive rats were all refractory to injected angiotensin after immunization. These results suggest a primary role for angiotensin in both forms of renal hypertension. PMID- 4307703 TI - Cultivation of a filterable agent associated with Marek's disease. PMID- 4307702 TI - Normal and abnormal regulation of beta-msh in man. AB - The regulation of plasma beta-melanocyte-stimulating hormone (beta-MSH) in man has been studied utilizing a radioimmunoassay previously described (1). In normal subjects plasma beta-MSH values ranged from 20 to 110 pg/ml. Metyrapone increased and dexamethasone decreased plasma beta-MSH levels. Surgical stress stimulated beta-MSH secretion. Plasma beta-MSH levels were elevated in patients with untreated Addison's disease and untreated congenital adrenal hyperplasia, and these levels fell to normal during glucocorticoid therapy. In patients with Cushing's syndrome due to pituitary adrenocorticotropic hormone (ACTH) excess, plasma beta-MSH was slightly elevated before treatment. In those patients who developed pituitary tumors and hyperpigmentation after bilateral adrenalectomy, plasma beta-MSH was greatly elevated. In patients with Cushing's syndrome due to adrenal tumor, plasma beta-MSH was subnormal. In patients with the ectopic ACTH syndrome, the levels of plasma beta-MSH were high. Plasma beta-MSH had a diurnal variation in normal subjects, patients with Addison's disease, and patients with congenital adrenal hyperplasia; but the normal diurnal variation was lost in patients with Cushing's disease. In patients with high plasma beta-MSH, simultaneous determinations of plasma ACTH showed close correlation between the degree of elevation of ACTH and that of beta-MSH. In extracts of tumors from patients with the ectopic ACTH-MSH syndrome the quantities of the two hormones were roughly equivalent. In patients with hyperpigmentation due to a variety of disorders other than pituitary-adrenal abnormalities, plasma beta-MSH was normal. It is concluded that the secretion of beta-MSH is regulated by the same factors that regulate ACTH. PMID- 4307704 TI - Carcinogenicity and metabolism of aromatic amines in the dog. PMID- 4307705 TI - Cellular analysis of liver carcinogenesis. 3. Comparison of the ultrastructure of hyperplastic liver nodules and hepatocellular carcinomas induced in rat liver by 2-fluorenylacetamide. PMID- 4307706 TI - Granular-cell myoblastoma of the larynx. PMID- 4307707 TI - Comparative stability of benzamide, salicylamide, and some N-substituted derivatives. PMID- 4307708 TI - Flavonoid antagonism of the spasmogenic effect of angiotensin, bradykinin, and eledoisin on guinea pig ileum. PMID- 4307710 TI - Tetrodotoxin-resistant electric activity in presynaptic terminals. AB - 1. The electric properties of the giant synapse in the stellate ganglion of the squid have been further investigated.2. During tetrodotoxin (TTX) paralysis, a local response can be elicited from the terminal parts of the presynaptic axons after intracellular injection of tetraethyl ammonium ions (TEA).3. The response is characterized by an action potential of variable size and duration, whose fall is often preceded by a prolonged plateau. The response, especially the duration of the plateau, is subject to ;fatigue' during repetitive stimulation.4. The TTX resistant form of activity is localized in the region of the synaptic contacts, and shows a marked electrotonic decrement even within less than 1 mm from the synapse. It is found only on the afferent, not on the efferent, side of the synapse.5. During the plateau of the response, the membrane resistance is greatly reduced below its resting value.6. The response depends on presence of external calcium and increases in size and duration with the calcium concentration. Strontium and barium substitute effectively for calcium. Manganese and, to a lesser extent, magnesium, counteract calcium and reduce the response. The response also declines, and ultimately disappears, if sodium is withdrawn for long periods.7. The relation of the local TTX-resistant response to the influx of calcium ions and to the release of the synaptic transmitter is discussed. PMID- 4307709 TI - The interaction of presynaptic polarization with calcium and magnesium in modifying spontaneous transmitter release from mammalian motor nerve terminals. AB - 1. The relationship between motor terminal polarization and miniature end-plate potential (m.e.p.p.) frequency was examined in the presence of various Ca, Mg and K concentrations ([Ca], [Mg] and [K]) and also at modified bathing osmolarity levels. The polarization changes were obtained with ;electrotonic' and ;focal' polarizing currents and with rapid changes in bathing [K].2. M.e.p.p. frequency increased exponentially with electrotonic depolarizing currents, but failed to decrease similarly with hyperpolarizing currents. An increase in bathing [K] to 15 mM increased the sensitivity of the terminals to presynaptic hyperpolarization.3. The slope, on semilogarithmic coordinates, of the function relating m.e.p.p. frequency to electrotonic polarizing currents (the release current function) was unchanged when bathing [Ca] was raised from 2 to 8 mM. When [Ca] was reduced to 0.5 mM the slope of this function was reduced initially but eventually approached the same slope as in control [Ca]. A similar effect was also found in the presence of 15 mM-KCl.4. The relationship between m.e.p.p. frequency and log [K], at various [Ca], resembled the relationships between m.e.p.p. frequency and presynaptic polarizing currents.5. An increase in bathing [Mg] or osmolarity had a similar effect to a reduction of [Ca].6. Tetrodotoxin (TTX) at a concentration of 10(-6) g/ml. was found to reduce m.e.p.p. frequency, at various [K], by a constant fraction of about 30%.7. In some of the junctions ;anodic break-down' was observed. An examination of this phenomenon with focal polarizing currents disclosed an unusual type of ;anodic break-down', with rapid ;on' and ;off' responses. This phenomenon may indicate that release depends on the influx of positively charged particles into the nerve terminals.8. It is concluded that nerve terminal depolarization accelerates exponentially the activity of a membrane component bearing three Ca molecules, the rate of acceleration being independent of bathing [Ca]. PMID- 4307711 TI - Treatment of otitis externa. Report of a clinical trial. PMID- 4307712 TI - Electron spin resonance of an irradiated single crystal of L-tyrosine-HC. AB - Analysis of the electron spin resonance (ESR) of a gamma-irradiated single crystal of L-tyrosine-HCl reveals a free radical formed by loss of an H from the hydroxyl group attached to the ring. Principal g values of the radical are g(x) = 2.0023 +/- 0.0005, g(y) = 2.0067 +/- 0.0005, and g(z) = 2.0045 +/- 0.0005, with g(x) perpendicular to the plane of the ring and g(y) along the CO bond to the ring. Analysis of the hyperfine structure of the spectra shows electron spin density on C((2)) and C((6)) to be 0.24 and on C((4)) to be 0.32. Corresponding spin densities calculated from molecular orbital theory are 0.26 and 0.31, respectively. PMID- 4307713 TI - Hyperfine structure from the four pyrrole nitrogens of heme. AB - Hemin and hematin have been incorporated into single crystals of the condensed ring planar hydrocarbon perylene, the approximate molecular ratio of heme to aromatic being 10(-3). X-ray diffraction and electron paramagnetic resonance (EPR) measurements indicate that these mixed crystals maintain their integrity when subjected to cryogenic temperatures and then returned to room temperature. EPR X-band orientation studies of single crystals at liquid helium temperature have revealed the following two important features: (1) presence of ligand hyperfine structure, which can be used to quantitate the distribution of unpaired metal electron on the ligands and (2) removal of the immediate fourfold symmetry of the ligand field about the metal, as evidenced by the rhombic character of the high-spin ferric system. The ligand hyperfine splittings have been interpreted as arising chiefly from an isotropic Fermi contact interaction. The observed splittings then indicate that 2.7 per cent of an unpaired spin is in each nitrogen 2s orbital. The g-values have been interpreted in terms of the spin Hamiltonian: [Formula: see text] which gives g(x,y) = 6.00 +/- 24E/D and g(z) = 2.00 - 34(E/D)(2). For various hemin and hematin sites these formulae for the g values are nicely obeyed when E/D is in the range 0.015 to 0.03. PMID- 4307714 TI - The relationship of DNA replication to the control of protein synthesis in protoplasts of T4-infected Escherichia coli B. AB - The relationship of DNA replication to the control of early enzyme synthesis and the formation of late proteins was studied in protoplasts of E. coli B cells infected with an amber mutant, T4am130. In this phage-host system the bacterial DNA is not completely degraded, and the onset and the extent of phage DNA synthesis could be regulated by use of 5-fluorodeoxyuridine and thymidine. It was found that DNA replication is necessary for the transcription of "late" regions of the phage genome and, thus, for the synthesis of late proteins. In addition, the sustained synthesis of late RNA and the tail-fiber protein was shown to require the continued replication of DNA. Furthermore, the mechanism regulating the cessation of early enzyme synthesis appeared to become operative shortly after the onset of DNA replication and required a limited amount of DNA synthesis for its full expression. PMID- 4307715 TI - Translocation of mRNA codons. I. The preparation and characteristics of a homogeneous enzyme. AB - This report describes a convenient scheme for the further purification of an E. coli enzyme which is required for the translocation step in protein biosynthesis. The homogeneous enzyme translocase appears to be a relatively large monomeric protein, having a molecular weight of approximately 72,000, and acts in a catalytic fashion during protein synthesis. It is also one of the major soluble macromolecular constituents of rapidly growing E. coli, comprising more than 2 per cent of the protein in ribosome-free extracts. Further, the rate of in vitro protein synthesis is linearly dependent upon the concentration of the pure enzyme until approximately one molecule of translocase is present per ribosome in reaction mixtures. PMID- 4307716 TI - Virus-specific nucleic acids in SV40-exposed hamster embryo cell lines: correlation with S and T antigens. AB - A number of homologous SV40-exposed hamster embryonic cell lines were examined for the presence of RNA complementary to SV40 DNA. Only those lines containing the SV40 T antigen were found to have such virus-specific RNA. In lines containing the SV40 S antigen, but not the SV40 T antigen, virus-specific RNA was not detected. These findings suggest that the S antigen is not coded for directly by the SV40 genome. PMID- 4307717 TI - A fluorescence probe of energy-dependent structure changes in fragmented membranes. AB - The reaction of the fluorochrome, 8-anilino-1-naphthalene-sulfonic acid (ANS), with fragmented membranes from beef heart mitochondria has been studied. ANS fluorescence is found to be enhanced 25-fold on binding to the membrane fragments in the absence of energy conservation, and this enhancement is increased to 35 fold in the membrane energized by substrate plux oxygen. The fluorescence of bound ANS depends upon the energy state of the membrane fragments, as indicated by the effects of ATP, substrates of the respiratory chain, oligomycin, and uncouplers. It is concluded that the changes of ANS fluorescence indicate structural changes of the mitochondrial membrane associated with energy conservation. The time course of energization is readily followed by ANS, and has a half-time of two seconds at 26 degrees . PMID- 4307718 TI - [The demonstration of brain tumors by means of scintillation camera]. PMID- 4307719 TI - [Remote effects of malignant tumors on the nervous system]. PMID- 4307720 TI - [Review of studies on viral oncolysis]. PMID- 4307721 TI - [Splenoportography in certain hepatic and splenic disorders in African Negroes]. PMID- 4307722 TI - [4 atypical cases of primary carcinoma of the liver]. PMID- 4307723 TI - [Bacterial flora of the urine in hospital environment. Investigation of 2,031 pathological cases]. PMID- 4307725 TI - A British abattoir survey of tumours in cattle, sheep and pigs. PMID- 4307724 TI - [Treatment of mental manifestations of chronic cerebral circulatory insufficiency. Clinical and psychometric study]. PMID- 4307726 TI - [Cancerogenic activity of diethylnitrosamine on pigs]. PMID- 4307728 TI - Glucose-6-phosphatase activity in primary rat liver tumors induced by high doses of 4-dimethylaminoazo-benzene. PMID- 4307727 TI - [Pathogenesis of renal sarcomas in rats by polyoma-virus]. PMID- 4307730 TI - [On the pathogenesis and treatment of fulminant and nutatory seizures in children]. PMID- 4307729 TI - [Metabolite analysis of rapidly growing DS-carcinosarcoma on the chick chorioallantois]. PMID- 4307731 TI - Histochemically observable alterations in enzyme pattern of rat myocardium, caused by parathion (E 605). PMID- 4307732 TI - Viral and Mycoplasma pneumoniae infections in exacerbations of chronic lung disease. PMID- 4307733 TI - An enzyme system of Mycobacterium tuberculosis that reacts specifically with isoniazid. I. PMID- 4307734 TI - Studies of a biochemical lesion in experimental tuberculosis in mice. X. Mitochondrial swelling induced by cord factor in vivo and accompanying biochemical change. PMID- 4307736 TI - Adaptation of the parainfluenza 3 (EA-106) virus to a new host. II. The EA-106 strain in cultures of L cells. PMID- 4307735 TI - Adaptation of the parainfluenza 3(EA--106) virus to a new host. I. Adaptation of the strain from tissue lines to the chick embryo. PMID- 4307737 TI - Avian reoviruses. I. Isolation and serological characterization. PMID- 4307738 TI - Avian reoviruses II. Physicochemical characterization and classification. PMID- 4307739 TI - Virus-like particles observed in plasma and white blood cells from birds with Marek's disease. PMID- 4307740 TI - Conformational evidence for the non-identity of cytochromes a and a3 in cytochrome oxidase. PMID- 4307741 TI - Detection and characterization of the phosphorylated form of microsomal glucose-6 phosphatase. PMID- 4307742 TI - Studies on in vitro RNA synthesis by chromatin fractions from rat liver and Novikoff hepatoma. PMID- 4307744 TI - Organophosphate spin-label studies of inhibited esterases, alpha-chymotrypsin and cholinesterase. PMID- 4307745 TI - A flavin-chlorophyll alpha complex resembling the P700 of photosynthesis. PMID- 4307743 TI - Enzymatic pyrophosphorylation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8 dihydropteridine by cell-free extracts of Escherichia coli B. PMID- 4307746 TI - The step sensitive to catabolite repression and its reversal by 3'-5' cyclic AMP during induced synthesis of beta-galactosidase in E. coli. PMID- 4307747 TI - Ultrastructural features of functioning alpha- and beta-cell tumors. PMID- 4307748 TI - Observations on the composition of certain colonic tumors. PMID- 4307749 TI - Contiguous glioblastoma multiforme and fibrosarcoma with extracranial metastasis. PMID- 4307750 TI - Nodular renal blastema. Definition and possible significance. PMID- 4307751 TI - Simultaneous hypoglycemia and acute congestive heart failure. PMID- 4307752 TI - [On the NAD and NADH2 content of the liver, heart, and kidneys of adrenalectomized and alcohol treated rats]. PMID- 4307753 TI - Angiotensin and norepinephrine efflux. PMID- 4307754 TI - [The role of immunity in the rejection of tumours induced by the MSV virus. The effect of antithymocyte serums]. PMID- 4307755 TI - Transformation of a mouse cell line by murine sarcoma virus (Moloney). PMID- 4307756 TI - Effect of herpes simplex virus on human embryonic cells latently infected with reovirus type 3. PMID- 4307758 TI - Carcinogenesis by avian sarcoma viruses. X. The decreased requirement for insulin replaceable activity in serum for cell multiplication. PMID- 4307757 TI - The stimulating effect of complete Freund's adjuvant on tumour induction by polyoma virus in mice and by Rous sarcoma virus in rats. PMID- 4307759 TI - A study of the neutralization of rhinoviruses by means of a plaque-reduction test. PMID- 4307760 TI - The immunologic response of the mouse to aerosols of an attenuated encephalomyocarditis virus strain. PMID- 4307762 TI - Release of gamma-aminobutyric acid into the fourth ventricle induced by stimulation of the cat's cerebellum. PMID- 4307761 TI - The effect of carrageenan on delayed hypersensitivity reactions. PMID- 4307763 TI - Incorporation of 32P in vitro into triphosphoinositide and related lipids of rat superior cervical ganglia and vagus nerves. PMID- 4307764 TI - P-nitrophenyl phosphatases of a membrane fraction from bovine cerebral cortex. PMID- 4307765 TI - Effect of mitomycin C on thymidine-methyl-H3 utilization by Entamoeba histolytica propagated in CLG medium. PMID- 4307766 TI - Carcinoma of cowper's gland: case report. PMID- 4307767 TI - Cancer of the nasopharynx. Review of the literature. Report of 72 cases. PMID- 4307768 TI - [Treatment of cutaneous porphyrias]. PMID- 4307769 TI - [Cytological and cytochemical changes of human malignant cells under the effect of inoculation with Trypanosoma cruzi in tissue culture]. PMID- 4307770 TI - Enzymatic release of phosphate from rat molar enamel by phosphoprotein phosphatase. PMID- 4307771 TI - Reduction of transmitter release by D-tubocurarine. PMID- 4307772 TI - [Psychiatric rehabilitation]. PMID- 4307773 TI - Avian pox in migrant and native birds in Panama. PMID- 4307774 TI - Copper metabolism. PMID- 4307775 TI - Biosynthesis of vitamin A from beta-carotene. PMID- 4307776 TI - [Peripheral paralysis caused by position]. PMID- 4307777 TI - [Electromyography of the posterior muscles of the neck in the prognosis of lesns of the brachial plexus]. PMID- 4307778 TI - [Compression of the posterior tibial nerve and plantar nerves. (So-called tarsal tunnel syndrome)]. PMID- 4307779 TI - [Biochemical properties of Schizosaccharomyces pombe depending on culture conditions and on the action of inhibitors. I. Study of phospholipids]. PMID- 4307780 TI - Kinetic, electrophoretic, and chromatographic studies on glucose-ATP phosphotransferases in rat hepatomas. PMID- 4307781 TI - Induction of brain tumors in newborn hamsters by simian adenovirus SA7. PMID- 4307782 TI - Glutaminase activities and growth rates of rat hepatomas. PMID- 4307783 TI - 1-methyl-1-nitrosourea and dialkylnitrosamine depression of nicotinamide adenine dinucleotide. PMID- 4307784 TI - Hematogenous metastasis of Yoshida ascites Hepatoma in the chick embryo liver: ultrastructural changes in tumor cells. PMID- 4307785 TI - Effect of feeding amino azo dyes on mitochondrial swelling and contraction. Kinetic evidence for deletion of membrane regulatory sites. PMID- 4307787 TI - Virus particles associated with the transplantable Novikoff hepatoma in the rat. PMID- 4307786 TI - Sequential alterations in mitochondrial inner and outer membrane electron transport and in respiratory control during feeding of amino azo dyes; stability of phosphorylation. Correlation with swelling-contraction changes and tumorigenesis threshold. PMID- 4307789 TI - The use of tris buffer for u.v. spectrophotometric assay of GOT and GPT. PMID- 4307788 TI - The source of the nothing dehydrogenase activity in normal serum. PMID- 4307790 TI - Viral and virus-like infections of the female genital tract. PMID- 4307791 TI - Specific transplantation resistance against mouse tumour induced by Mouse Sarcoma Virus (Harvey). PMID- 4307792 TI - Karyological analysis of mouse and rat embryo cells transformed by Murine Sarcoma Virus (Harvey). PMID- 4307793 TI - Report of the panel for the symposium on immunity to selected equine infectious diseases. PMID- 4307794 TI - Immunology of equine influenza. PMID- 4307795 TI - The evaluation of an experimental bivalent equine influenza virus vaccine. PMID- 4307796 TI - On immunity to disease caused by equine herpesvirus 1. PMID- 4307798 TI - Comments on equine herpesvirus infection (equine rhinopneumonitis) and bovine herpesvirus infection (infectious bovine rhinotracheitis). PMID- 4307797 TI - Comparative aspects of immunity against bovine and equine herpesviruses. PMID- 4307799 TI - Biological requirements and control of equine rhinopneumonitis vaccine (live virus). PMID- 4307802 TI - Attitudes of professional nonpsychiatric nurses toward mental illness. PMID- 4307800 TI - Comments on biologic requirements and control of equine rhinopneumonitis vaccine. PMID- 4307804 TI - Creativity with retardation. PMID- 4307803 TI - Service occupation workers preference change and stereotype reduction toward their clients. PMID- 4307801 TI - The dilemma of the alcoholic patient in a psychiatric hospital. PMID- 4307805 TI - Nursing action guide: hallucinations. PMID- 4307806 TI - Psychology, extended care facility, and the community. PMID- 4307808 TI - Psychiatric drugs and trends. Slang terms of drug abusers. PMID- 4307807 TI - Nursing in Greece. PMID- 4307809 TI - Geriatrics. PMID- 4307811 TI - Social problems involved in treating cancer of the larynx. PMID- 4307810 TI - [Experimental studies of the morphology and function of isolated liver perfused with autologous and heterologous blood with special reference to the clearing of the blood of jaundiced patients]. PMID- 4307812 TI - Enterovirus infections of the central nervous system. PMID- 4307813 TI - Iatrogenic modification of tissue responses to infectious agents in the central nervous system. PMID- 4307814 TI - Experimental strangulated intestinal obstruction. PMID- 4307815 TI - [A radiographic study of the wrist bones of obese children]. PMID- 4307816 TI - Platelet adhesiveness in normal and bleeder swine as measured in a Celite system. PMID- 4307817 TI - Glomerular (azotemic) osteodystrophy. PMID- 4307818 TI - Separation and characterization of HeLa alkaline pyrophosphatase isoenzymes. PMID- 4307819 TI - Studies on the subunit structure of rabbit liver fructose diphosphatase. PMID- 4307820 TI - The effects of pyridoxal phosphate on rabbit liver and kidney fructose 1,6 diphosphatases. PMID- 4307821 TI - Phosphoserine phosphatase distribution in normal and neoplastic rat tissues. PMID- 4307822 TI - The possible relationship between ultrastructure and biochemical state of heart mitochondria. PMID- 4307823 TI - Spin-labeled hapten studies of structure heterogeneity and cross-reactivity of the antibody active site. PMID- 4307824 TI - Transformation of mevalonic acid into isoprenoid compounds by enzymes from Pinus radiata. Activation of the overall reaction by phospholipids. PMID- 4307826 TI - Nucleosidediphosphatase activity in plasma membrane of rat liver. PMID- 4307825 TI - Hypoglycemic peripheral neuropathy. PMID- 4307827 TI - Peripheral pathways and properties of uterine afferents in the cat. PMID- 4307828 TI - The bacterial metabolism of flavonoids: hydroxylation of taxifolin. PMID- 4307829 TI - Countercurrent distribution of inosol lipids of plant seeds. AB - The inositol lipids of plant seeds consist of phosphatidyl inositol, the phytoglycolipids, and a previously uncharacterized ceramide-phosphate polysaccharide. These three species have been separated from each other and from the common glycerophosphatides by a series of simple countercurrent distributions, first as the naturally occurring Ca-Mg salts and subsequently in the Na salt form. The new ceramide-phosphate-polysaccharide is present in each of the four plant phosphatides examined (corn, soybean, flax, safflower). It is devoid of glucosamine but contains the other carbohydrate components commonly found in the phytoglycolipids. The basic structural unit of the new glycolipid consists of a ceramide-phosphate-inositol-hexuronic acid moiety to which the other sugars (galactose, mannose, arabinose) are attached. Flax ceramide phosphate-polysaccharide has fucose in addition to the other sugars. PMID- 4307830 TI - The mechanism of heparin stimulation of rat adipocyte lipoprotein lipase. AB - Free fat cells and stromal-vascular cells were prepared from rat adipose tissue by incubation with collagenase. NH(4)OH-NH(4)Cl extracts of acetone-ether powders prepared from fat cells contained lipoprotein lipase activity but extracts of stromal-vascular cells did not. Intact fat cells released lipoprotein lipase activity into incubation medium, but intact stromal-vascular cells did not. The lipoprotein lipase activity of the medium was increased when fat cells were incubated with heparin, and this was accompanied by a corresponding decrease in the activity of subsequently prepared fat cell extracts. Heparin did not release lipoprotein lipase activity from stromal-vascular cells. The lipoprotein lipase activity of NH(4)OH-NH(4)Cl extracts of fat cell acetone powders is increased by the presence of heparin during the assay. This increase is not due to preservation of enzyme activity, but to increased binding of lipoprotein lipase to chylomicrons. Protamine sulfate and sodium chloride have little effect on the binding of lipoprotein lipase to chylomicrons, but they inhibit enzyme activity after binding to substrate has occurred. These inhibitors do, however, inhibit the stimulatory effect of heparin on enzyme-substrate binding. PMID- 4307831 TI - Metabolism of cholesterol in the tissues and blood of the chick embryo. AB - Three artificially inseminated laying White Leghorn hens were given 35-50 micro c of cholesterol-4-(14)C intravenously. Their subsequently produced eggs contained cholesterol-(14)C-labeled yolks. Some of the fertilized eggs were analyzed for cholesterol content and radioactivity. Other eggs were incubated until hatching. The specific activity of the cholesterol contained in the serum and tissues of newly hatched chicks was determined and compared with that of yolk sac, which was taken as representative of egg yolk cholesterol before its metabolic transfer into the chick embryo. The specific activities of cholesterol in intestine, liver, serum, heart, and skeletal muscle and the whole chick were 95-98% of that in yolk sac, but that of brain cholesterol was only 11% of this value. These results indicate that whereas most of the cholesterol in the chick originated from the egg yolk, cholesterol biosynthesis was active in the brain and provided about 90% of its cholestero content. Newly hatched chicks were found to be hyperlipemic compared with older chicks and had fatty livers with a high cholesterol content. Desmosterol was found in 9- and 15-day old chick embryos but not in the newly hatched chicks, in which the only sterol was cholesterol. PMID- 4307832 TI - Long-chain bases in the sphingolipids of atherosclerotic human aorta. AB - Long-chain bases were prepared from human aorta sphingomyelin by a combined enzymatic hydrolysis-alkaline hydrolysis procedure and these bases were isolated by thin-layer chromatography. Aldehydes, obtained from the long-chain bases by periodate oxidation, were converted to 1,3-dioxolane derivatives. Dioxolanes were identified and quantified by gas-liquid chromatography before and after catalytic hydrogenation, and before and after separation into saturated, monoene, and diene dioxolane fractions. The monoene dioxolanes were converted to aldehydes by reductive ozonolysis with dimethyl sulfide and these aldehydes were isolated and identified as dioxolane derivatives. The double bond positions in the major diene component were established by reductive ozonolysis and permanganate-periodate oxidation. Sphingenines in the cerebroside-sulfatide and sulfatide fractions of aorta were converted to aldehydes by the reductive ozonolysis of intact sphingolipids and these aldehydes were analyzed as the dioxolanes. Human aorta sphingomyelin contained significant amounts of 4-hexadecasphingenine, 4 heptadecasphingenine, sphinganine, 4-sphingenine, and 4,x14-sphingadienine. Small amounts of hexadecasphinganine, 4-tetradecasphingenine, a sphingadienine isomer, an unknown sphinganine, and two unknown diene long-chain bases were also found in sphingomyelin. The presence of a branched-chain 4-sphingenine was tentatively established and the possible presence of a sphingenine isomer was suggested. The major sphingenines were the same in the sphingomyelin, sulfatide, and cerebroside sulfatide fractions of human aorta. PMID- 4307833 TI - Separation of neutral lipids of shark liver by "dry-column" chromatography. AB - "Dry-column" chromatography in mixed solvents has been successfully used to separate gram quantities of neutral lipids from shark liver oil into simpler fractions. PMID- 4307834 TI - Dry-column chromatographic isolation of fatty acid esters of phorbol from croton oil. AB - The family of mixed fatty acid esters of 4,9,12,13,20-pentahydroxy-tiglia-1,6 dien-3-one (phorbol) has been isolated from croton oil by column chromatography on silica gel and preparative dry-column chromatography on silica gel HF/254 packed in a cellophane membrane. The tumorpromoting agents are obtained rapidly and with minimum difficulty. PMID- 4307835 TI - [Ulgastrin rolling cure for the treatment of inflammatory diseases of the gastrointestinal tract]. PMID- 4307836 TI - [Laboratory diagnosis of cytomegaly]. PMID- 4307837 TI - Attempts to cultivate the equine infectious anemia virus in various types of cells. PMID- 4307838 TI - Arrhenoblastoma: case report. PMID- 4307839 TI - [Pancreatogenic hypoglycemia]. PMID- 4307840 TI - [Primary quadruple carcinoma]. PMID- 4307841 TI - [Hormonally active ovarian tumors in rabbits induced with methylcholanthrene 2 years after the experiment]. PMID- 4307842 TI - [Concerning the usefulness of cytochemical and electronmicroscopic studies for the evaluation of the grade of damage of live cells in human biopsy material]. PMID- 4307843 TI - [Biological function of quinones]. PMID- 4307844 TI - [Viral diarrhea]. PMID- 4307845 TI - [On the mechanism and function of DNA-ligases]. PMID- 4307846 TI - Free radicals formed in aliphatic polyamino acids by exposure to hydrogen atoms. PMID- 4307848 TI - [XYY constitution]. PMID- 4307847 TI - Microangiopathic haemolytianaemia. PMID- 4307850 TI - The influence of the renin-angiotensin system on renal function: possible role in advanced liver disease. PMID- 4307849 TI - [Multiple cancers (apropos of 100 cases)]. PMID- 4307852 TI - [Electrophysiological analysis of the effect of serotonin upon the sympathetic ganglia during changes in blood sugar level]. PMID- 4307851 TI - Conjugation of steroid hormones by breast-cancer tissue and selection of patients for adrenalectomy. PMID- 4307853 TI - [On the problem of the loss of electric charges by quartz-containing dust in the upper respiratory tract]. PMID- 4307854 TI - [Disinfection of drinking water containing enteroviruses, by products of sodium chloride electrolysis]. PMID- 4307855 TI - [Sanitary-virologic and bacteriologic characteristics of sewage water, mud and soil in suburban zones of Kiev]. PMID- 4307856 TI - [The use of infrared spectrophotometry for detecting the fumes of polymethylsiloxane fluid in the air]. PMID- 4307857 TI - Site of action of venom of Microbracon hebetor Say (Braconidae, Hymenoptera). PMID- 4307858 TI - [On the origin of serum phosphatase in glycosuria]. PMID- 4307859 TI - Relation of virus-induce cell fusion and chromosome pulverization to mitotic events. PMID- 4307861 TI - Skeletal and reticular tissue disorders produced in mice by agent(s) from Sarcoma 37. PMID- 4307860 TI - Survival in childhood malignancies: assessment of the influence of age, sex, and tumor type, with emphasis on "long-term survivors". PMID- 4307862 TI - Rates of albumin and transferrin synthesis in vitro in rat hepatoma-derived H4II EC cells. PMID- 4307864 TI - Report on 141 childhood malignancies observed in Jamaica. PMID- 4307865 TI - Growth and nucleic acid synthesis in normal cells and cells infected with Rous sarcoma virus. PMID- 4307863 TI - Biochemical, pathological, and genetic aspects of a spontaneous mouse hepatoma. PMID- 4307866 TI - Influence of hormones on N-2-fluorenyldiacetamide-induced hyperplastic hepatic nodules in rats. PMID- 4307867 TI - Canine papilloma: the structural characterization of oral papilloma virus. PMID- 4307868 TI - Reproductive capacity and viability at higher temperatures of various transformed hamster cell lines. PMID- 4307869 TI - [Alcoholic steatosis of the liver. II. Study of various metabolic effects of fructose perfusion alone or associated with alcohol in normal humans]. PMID- 4307870 TI - [Cells with lipid inclusions on the border of pulmonary alveoli. Histochemical and ultrastructural study]. PMID- 4307871 TI - "Rescued" SV40: increased transforming efficiency in mouse and human cells. AB - Plaque-size mutants of simian virus 40 (SV40) have been characterized with respect to their ability to transform mouse and human cells in vitro. Large plaque mutants of SV40 were extremely inefficient at transforming mouse or human cells, requiring approximately 50 times more infectious particles per transformation event than did the small plaque mutants. The minute plaque SV40 was the most efficient, requiring less than 10(3) plaque-forming units per transformation in mouse Balb/3T3 cells and only 1.5 x 10(4) plaque-forming units per transformation unit in the "susceptible" human strains. Both small and minute plaque virus were unable to help the large plaque virus to transform. Virus "rescued" from transformed 3T3 cells by cocultivation with monkey kidney cells was more efficient at transformation than the parental type. The increased efficiency could be shown for each plaque type and in human as well as in mouse cells. The property of "high efficiency transformation" is stable through at least two passages in monkey kidney cells. PMID- 4307873 TI - Surface-specific characteristics of a contact-inhibited cell line containing the SV40 viral genome. AB - A cytoagglutinin purified from wheat germ lipase agglutinated five related murine fibroblast cell lines in the order of their saturation densities. One cell line, which was transformed by the oncogenic papova virus SV40 but which had a low saturation density, agglutinated poorly. Preincubation of cells with trypsin increased their agglutinability, but trypsin made no cell line more agglutinable than the cell line with the highest saturation density. PMID- 4307872 TI - The role of individual spleen cells in the interferon response of the intact mouse. AB - A method is described for the detection of interferon production by individual spleen cells of mice after intravenous virus infection. Although mouse spleen plays a major role in the total interferon response to Newcastle disease virus, the number of spleen cells participating is a small fraction of the total, suggesting that interferon formation is to some extent a specialized cell function. Monolayers of mouse embryo cells, after brief contact with agar suspended spleen cells from interferon-producing mice, have roughly circular foci of cells remaining after removal of agar and vesicular stomatitis virus challenge. The numbers of such foci correlate directly with the number of spleen cells, concentration of inducing virus in the inoculum, duration of contact of cells with mouse-embryo indicator monolayers, time after interferon induction, and serum interferon titer. With this technique, evolution of the interferon forming cell response in spleens of virus-infected mice has been studied. PMID- 4307874 TI - Spin-labeled transfer RNA. AB - The alpha-amino group of valyl-tRNA has been combined chemically with a nitroxide spin label through an amide linkage. This spin-labeled aminoacyl-tRNA has an electron paramagnetic resonance spectrum which reflects the mobility of the aminoacyl end of the tRNA molecule. The rate of tumbling of the spin label has been measured as a function of temperature and ionic strength. An abrupt transition in the nature of the motion occurs at a temperature which is sensitive to the ionic strength of the medium. This change in behavior of the aminoacylated spin label occurs at the same temperature as the midpoint of the optical density melting curves in dilute salt solutions. However, when denaturing agents such as dimethylsulfoxide or urea are added to the solution, the spin melting temperature is lower than the melting temperature as measured by the change in optical density. This suggests that under these conditions the local region of the aminoacyl end of the molecule denatures before the rest of the molecule is disrupted. PMID- 4307875 TI - An ESR study of the reaction of OH. free radical with cysteine and related sulfhydryl compounds. UCLA-12-686. PMID- 4307876 TI - [Derivatives of viomycin. 3. Viomycin-methyltetracyclines, their preparation and properties]. PMID- 4307877 TI - Studies of the renin-angiotensin-aldosterone system in patients with hypertension and in normal subjects. PMID- 4307878 TI - Correction of malignant hypertension and returen of renal function following late renal artery embolectomy. PMID- 4307879 TI - Procedure for the evaluation of the virucidal effectiveness of an ethylene oxide gas sterilizer. AB - A quantitative, reproducible method was developed for the evaluation of the virucidal activity of test gases. Using this method, we determined the virucidal effectiveness of a Steri-Vac ethylene oxide gas sterilizer. Wool gabardine material was exposed to high concentrations of herpes simplex, vaccinia, parainfluenza, or polio viruses and was processed through the sterilizer. Two time-temperature cycles of the machine, 29 C for 180 min and 60 C for 48 min, were used in separate experiments. The viruses were exposed to the gas when freshly pipetted onto the fabric or when pipetted on the material and allowed to dry 16 to 24 hr. In two experiments carried out under each condition, the virus titers were reduced by the sterilization process to less than detectable limits. These titer reductions were for the herpes virus >/= 2.7 to 5.0 log, for vaccinia virus >/= 4.0 to 6.1 log, for parainfluenza virus >/= 1.8 to 4.9 log, and for poliovirus >/= 4.9 to 7.7 log. The observed reductions in virus titers were the same whether the virus-contaminated fabrics were sealed in polyethylene packages or held in open petri dishes during exposure to ethylene oxide. PMID- 4307880 TI - Propagation of MM virus in L cells. AB - MM virus (mouse-brain stock) replicated to a limited extent in L cells without cytopathic effects; the average yield was less than 1 plaque-forming unit/cell. Passage in BHK-21 cells resulted in MM virus [MM(BHK)] which replicated to high titers (200 to 300 plaque-forming units/cell) in L cells with complete cytopathic effects. Appearance of mature MM(BHK) virus in L-cell cultures begins 4 hr after infection and is completed by 8 hr. Release of mature virus was slow (less than 1% at 8 hr) but was completed by 24 hr. PMID- 4307881 TI - Propagation of MM virus in continuous cell lines. AB - Baby hamster kidney (BHK), McCoy, and L cell lines were found to be suitable for isolation of MM virus from infected mouse brain tissue. The virus was recovered in high titer in the first passage in BHK and McCoy cells, with concomitant cytopathic effect (CPE). In L cells, virus yield was lower than in the other two cell lines and CPE was incomplete. Adaptation of the virus to BHK and McCoy cells by serial passages was evidenced by accelerated development of the CPE and increase in the virus titer. Plaques were obtained in all three cell lines when inoculated with infected mouse brain or with the tissue culture-propagated virus. In the BHK cells, the virus release preceded the appearance of CPE and maximal yield of virus was obtained after 1 to 3 days of incubation, depending on the size of inoculum. The BHK-propagated virus had the same lethality for mice as did the mouse brain-propagated stock, and there was no difference in the course of the disease caused by the two preparations. PMID- 4307882 TI - Biochemical and clinical characteristics and antibiotic susceptibility of atypical Enterobacter cloacae. AB - The characteristics of an atypical group of the family Enterobacteriaceae resembling Enterobacter cloacae were studied. The urinary tract was the most common source of these organisms, and most strains represented infections of secondary clinical significance. In contrast to typical Enterobacter strains, the atypical strains were highly susceptible to the cephalosporins; otherwise, there was a high degree of susceptibility to five other antibiotics and resistance to ampicillin except in very high concentration. PMID- 4307884 TI - Dapsone and peripheral motor neuropathy. PMID- 4307883 TI - Yellow fever vaccine. II. Antigenicity and neurovirulence of a vaccine seed free from avian leukosis virus. AB - Avian leukosis virus (ALV)-free candidate primary and secondary seed lots were indistinguishable from corresponding ALV-contaminated lots with respect to (i) potency as measured by titration in newborn and weanling mice and in the MA-104 plaque system, (ii) degree of viscerotropism as measured by viremia in monkeys, (iii) neurotropism as determined by the monkey neurovirulence test, and (iv) potency as determined by antibody response in monkeys inoculated by the intracerebral route. PMID- 4307885 TI - Granular cell myoblastoma. PMID- 4307886 TI - The incidence of neoplastic trophoblastic disease in Australia. PMID- 4307887 TI - [Serological diagnosis of human amebiasis using the fluorescent antibody technic]. PMID- 4307888 TI - A structural basis for the transphosphorylation of nucleotides with hydroxyapatite. PMID- 4307889 TI - Sensitivity of newborn mice to carcinogenic agents. PMID- 4307890 TI - Nitrosoamines: a jig-saw puzzle with missing pieces. PMID- 4307891 TI - Carcinogen testing in the new-born mouse. PMID- 4307892 TI - [On the characteristics of strains of Cl. perfringens as agents of food toxinfections]. PMID- 4307893 TI - [Quantitative determination of Cl. perfringens on objects of the external environment]. PMID- 4307895 TI - Effect of temperature on the formation of radicals by hydrogen-atom bombardment. PMID- 4307894 TI - Diabetes mellitus initially presenting as peripheral neuropathy in the upper limb. PMID- 4307896 TI - Cyclic 3',5'-nucleotide phosphodiesterase in brain. PMID- 4307897 TI - The role of histochemical and biochemical preparation methods for the detection of glycogen. PMID- 4307899 TI - Patterns of infections with adenovirus types 4, 7 and 21 in military recruits during a 9-year survey. PMID- 4307900 TI - Granular cell myoblastoma of the esophagus. A case report. PMID- 4307898 TI - The reducing action of elastic tissue in ferric ferricyanide. A histochemical analysis. PMID- 4307901 TI - Adrenal catecholamine and cortisol secretion during extracorporeal circulation in dogs. PMID- 4307902 TI - Immunofluorescence in the study of Marek's disease. I. Detection of antigen in cell culture and an antigenic comparison of eight isolates. AB - The indirect fluorescent-antibody (FA) test was applied to the detection of Marek's disease (MD) antigen in cell culture and antibody in the serum of birds. For the detection of antigen, sera were obtained from birds hyperimmunized with the JM strain of MD. MD antigen could be detected in the nucleus and in the cytoplasm of duck and chick embryo fibroblasts and in those of chick kidney cells infected with material known to contain the MD virus. Uninoculated cultures of chicken cells were always free of MD antigen. When chick kidney cells were infected with a stock cellular preparation of MD virus, infected cells could be detected after 24 hr with the FA test. At this time no cytopathological areas were seen by conventional light microscopy. By 7 days after infection, the same number of infected areas were detected by both methods, and the fluorescent areas coincided with the cytopathological areas. This indicates that the fluorescent areas and the areas with cytopathology are caused by the same agent. A straight line relationship between the dilution of inoculum and the number of fluorescent or morphological foci obtained indicates that one infectious unit produced one fluorescent or morphological focus. In addition, this time sequence study confirmed the cell association of the virus and demonstrated the cell-to-cell spread of infection. Cell cultures inoculated with eight different isolates of MD were tested in all combinations with sera prepared against the same isolates. The antigens were indistinguishable from one another, indicating that either the strains are antigenically identical or there is a common antigen or contaminant in all of them so that they stained equally well. The FA test can detect MD antigen before cytopathological areas develop in cell culture; however, the small size of the area usually examined precludes its use in initial isolations in which only a small number of infectious units are present in the inoculum. MD infected cells contain a heat-stable antigen similar to that found in herpes simplex-infected cells. PMID- 4307903 TI - Effect of ultraviolet irradiation and actinomycin D on polyoma virus replication in mouse embryo cell cultures. AB - Ultraviolet irradiation and actinomycin D impair the capacity of mouse embryo (ME) cells to support the replication of polyoma virus, but not of encephalomyocarditis (EMC) virus. The loss in capacity for polyoma virus synthesis was an "all-or-none" effect and followed closely upon the loss in cellular capacity for clone formation. Cells treated with either agent produced polyoma "T" antigen, but did not synthesize polyoma structural protein. Infection of untreated ME cells with polyoma virus produced marked stimulation of both deoxyribonucleic acid (DNA) synthesis and ribonucleic acid (RNA) synthesis. ME cell cultures irradiated with ultraviolet for 30 sec at 60 muw/cm(2) or treated with actinomycin D at 0.1 mug/ml for 6 hr prior to infection were incapable of synthesizing DNA or RNA, even after infection with polyoma virus. Irradiation of cells during infection produced cessation of synthesis of both RNA and DNA. Addition of actinomycin D during infection did not inhibit DNA synthesis but abolished RNA synthesis and reduced the yield of polyoma virus to 10% of that in untreated infected cultures. Both agents lost the ability to prevent replication of a full yield of polyoma virus when administered 30 hr after infection or later. The period after which neither agent inhibited polyoma replication corresponded with the period at which maximal RNA synthesis in untreated infected cultures had subsided. It can be concluded on the basis of the data presented that the functional integrity of the mouse embryo cell genome is required for the replication of polyoma virus, but not for EMC virus. Whereas the requirement for cellular DNA-dependent RNA synthesis for polyoma virus replication has been demonstrated, the exact nature of the host-cell function remains to be elucidated. PMID- 4307904 TI - Protein composition of the structural components of vesicular stomatitis virus. AB - Digitonin, a sterol glycoside which complexes with cholesterol, stripped off the envelope of vesicular stomatitis (VS) virions and liberated two viral structural proteins, 83% of P6 and 53% of P4. Deoxycholate also disrupted VS virions but released nucleocapsid cores which could be identified by higher buoyant density, ratio of incorporated (3)H-uridine to (14)C-protein, and electron microscopy. The major nucleocapsid protein was P5 but varying amounts of the minor protein aggregate P2 were present, depending on the concentration of urea used for extraction. P2 appeared to be a polymer of P5. Two other minor structural proteins, P1 and P3, could not be located in the virion. From these data, we conclude that the three microscopically identifiable structures of VS virions are each composed primarily of a single major protein, as follows: P6 = envelope protein, P4 = protein of underlying "shell," and P5 = nucleocapsid protein. PMID- 4307905 TI - Fusion of vesicular stomatitis virus with the cytoplasmic membrane of L cells. AB - At an early stage in infection, vesicular stomatitis viruses were attached to the surface of L cells by fusion of the viral and cell membranes. PMID- 4307906 TI - Encephalomyocarditis virus ribonucleic acid polymerase associated with 150S cytoplasmic particles. AB - Cytoplasmic particles which sedimented at 150S were the smallest structures containing detectable viral ribonucleic acid polymerase in mouse cells infected with encephalomyocarditis virus. PMID- 4307908 TI - Double-blind, cross-over study comparing chlordiazepoxide, conjugated estrogens, combined chlordiazepoxide and conjugated estrogens, and placebo in treatment of the menopause. PMID- 4307909 TI - Role of psychotropic therapy in estrogen-deficient menopausal patients. PMID- 4307907 TI - [Surgery of primary hepatoma--clinical course and significance of hepatic resection]. PMID- 4307911 TI - [Clinical study of bone metastases of prostatic tumor]. PMID- 4307910 TI - Effect of endocrines on central nervous system. I. PMID- 4307912 TI - [The diagnosis of acute gynecologic abdomen in relation to its clinico radiological findings. IV. Acute clinico-radiological pattern due to adnexal neoformations: ovarian cysts and cystomas; primary neoplastic processes of the ovary]. PMID- 4307913 TI - [Further results obtained with histochromatographic technics applied to nerve tissue]. PMID- 4307914 TI - Acetylcholine action: biochemical aspects. PMID- 4307915 TI - Quantal secretion from adrenal medulla: all-or-none release of storage vesicle content. AB - Neurogenic secretion of catecholamines from the adrenal medulla in rabbits, induced by administration of insulin, caused decreases in both the dopamine-beta hydroxylase activity and the catecholamine content of the storage vesicle fraction. After sedimentation through a sucrose density gradient, the storage vesicles obtained from insulin-treated animals had the same density and the same ratio of dopamine-beta-hydroxylase to catecholamine as did vesicles from untreated animals. These and other data indicate that neurogenic secretion from the adrenal medulla occurs by an all-or-none release from the storage vesicles. PMID- 4307916 TI - Juvenile angiofibroma. PMID- 4307918 TI - Granular cell myoblastoma. Clinicopathologic study of forty-two patients. PMID- 4307919 TI - Vesicular stomatitis virus infections in Panamanian primates and other vertebrates. PMID- 4307920 TI - Arousal and nonarousal enuretic events. PMID- 4307921 TI - [Research on the etiologic agent of human viral hepatitis]. PMID- 4307923 TI - Recent studies othe possible role of viruses in human cancer. PMID- 4307922 TI - Metabolism and function studied in single neurones. PMID- 4307924 TI - [Enzyme activity of the liver in rats with chronic carbon tetrachloride poisoning]. PMID- 4307925 TI - [Research on the infectious bovine rhinotracheitis virus in Italy]. PMID- 4307926 TI - [Vasoactive polypeptides from blood substrates]. PMID- 4307927 TI - Cytomegalovirus hepatitis in an adult. An autopsy report. PMID- 4307928 TI - Biosynthesis of chlorophylls. PMID- 4307929 TI - Relation between the concentration of ATP and that of NADH and excess porphyrin formation in the liver of rats during experimental porphyria. PMID- 4307930 TI - Congenital cytomegalic inclusion disease following intrauterine transfusion. AB - Congenital cytomegalic inclusion disease occurring in two infants who received intrauterine transfusions for severe haemolytic disease due to rhesus isoimmunization may have been transmitted in the donor blood. PMID- 4307932 TI - Electron spin resonance study of the free radicals of 3-methylcholanthrene oxi derivatives. PMID- 4307931 TI - Relapsing amoebic colitis of 12 year's standing exacerbated by corticosteroids. PMID- 4307933 TI - Effects of trypsin on replication of parainfluenza-3 virus in HEp-2 cell cultures. PMID- 4307934 TI - Aldehyde dehydrogenase in pseudomonads. PMID- 4307935 TI - [Advances and problems of ACTH measurement]. PMID- 4307936 TI - Practically applicable results of twenty years of research in endocrinology. PMID- 4307937 TI - [Some results of a sanitary-virological survey of environmental objects]. PMID- 4307938 TI - Evidence for a methionyl residue in the active site of the cytoplasmic malate dehydrogenase from pig heart. PMID- 4307939 TI - Phosphatase activity of coagulase-positive and coagulase-negative staphylococci and their correlation with pathogenicity. PMID- 4307940 TI - Transplacental transmission of polio antibodies--flocculating and neutralizing. PMID- 4307941 TI - Evaluation in clinical practice of the fluorescent amoebic antibody test. AB - Serum fluorescent antibody levels against Entamoeba histolytica were determined in patients with amoebic infection and in control cases. Titres of 1: 64 or above were obtained only in cases of active or recent amoebic infection, and were recorded in 75.0% of intestinal cases and in 95.2% of extraintestinal cases. Titres given by symptomless carriers of Entamoeba histolytica, though not exceeding 1: 32, were proportionately higher than those obtained in normal subjects or in patients with non-amoebic disorders. PMID- 4307942 TI - A case of fatal Clostridium welchii toxaemia due to ward infection. PMID- 4307943 TI - Incubation of cerebral microsomes with [3H] acetyl phosphate. PMID- 4307945 TI - Wilms' tumor. A current plan of treatment. PMID- 4307944 TI - A technique for functional liver autotransplantation. Observations on survival, function, and regeneration of the autotransplant. PMID- 4307946 TI - Radiotherapy of Wilms' tumor and neuroblastoma. PMID- 4307947 TI - Herpes encephalitis. I. The clinical picture. PMID- 4307948 TI - Herpes encephalitis. II. Pathology of herpes encephalitis. PMID- 4307949 TI - Naturally occurring carcinogens in foods. PMID- 4307950 TI - Mode of action of DDT and allethrin on nerve: cellular and molecular mechanisms. PMID- 4307951 TI - Comparative chronic inhalation toxicity of beryllium ores, bertrandite and beryl, with production of pulmonary tumors by beryl. PMID- 4307952 TI - The metabolic and bactericidal defect in chronic granulomatous disease. PMID- 4307953 TI - The search for human hepatitis virus. PMID- 4307954 TI - A critical review of methodology of sleep learning experiments. PMID- 4307955 TI - Monoamines and the EEG stages of sleep. PMID- 4307956 TI - The influence of centrophenoxine (Lucidril) on the course of sleep deprivtion in alcoholics. PMID- 4307958 TI - Nocturnal sleep of hypersomniacs. PMID- 4307959 TI - The sleep cycle duration in normal and epileptic cats and humans. PMID- 4307957 TI - "Pickwickian syndrome" and the influence of weight reduction on the clinical state and polygraphic picture. PMID- 4307960 TI - A hand-operated, ultrasound scan system for ophthalmic evaluation. PMID- 4307961 TI - [The clinical picture and surgical prospects of rapidly growing gliomas]. PMID- 4307963 TI - Experimental design in clinical drug research: some practical implications. PMID- 4307962 TI - [Demonstration of brain tumors using scintigraphy]. PMID- 4307965 TI - Treatment of ophthalmic hemorrhage by premarin. PMID- 4307964 TI - Gram negative infections in burns and their chemotherapy. PMID- 4307966 TI - [Clinical studies with a synthetic ACTH]. PMID- 4307967 TI - [An interferon-inducing substance in extract from rous sarcoma]. PMID- 4307968 TI - How are insect circadian rhythms controlled? PMID- 4307969 TI - Cyclic AMP regulates catabolite and transient repression in E. coli. PMID- 4307970 TI - Inhibitory effect of interferon on murine sarcoma and leukaemia virus infection in vitro. PMID- 4307971 TI - Chromosome changes in human cells induced by herpes simplex, types 1 and 2. PMID- 4307972 TI - Effect of barbiturates on dream content. PMID- 4307973 TI - Granular-cell myoblastoma of the hard palate. PMID- 4307974 TI - Respiratory changes during seed germination. Histological distribution of respiratory enzymes and mobilization of fat reserves in castor bean endosperm and peanut cotyledons. AB - Germinating peanut cotvledons and germinating castor bean endosperm have been compared with respect to their rates of fat dissimilation and with respect to the anatomical distribution of respiratory activity. The lipid mobilization is much slower in peanut cotyledons than in castor bean endosperm. Light has essentially no effect on either system. As germination progresses, the majority of the succinic dehydrogenase and cytochrome oxidase activities become localized in the vein regions of peanut cotyledons. In the castor bean endosperm these two activities are uniformly distributed throughout the storage parenchyma and increase with germination until the organ becomes soft and visibly senescent. PMID- 4307975 TI - Neoplastic transformation of hamster astrocytes in vitro by simian virus 40 and polyoma virus. AB - Astrocytes in cultures of brain cells from fetal or newborn hamsters undergo neoplastic transformation after infection with simian virus 40 or polyoma virus. Subcutaneous or intracerebral inoculation of the transformed brain cells into newborn or adult hamsters produces progressively enlarging astrocytomas at the sites of injection. Astrocytomas produced by polyomatransformed cell lines are histologically better differentiated, but grow more rapidly and metastasize more frequently, than astrocytomas produced by cell lines transformed by simian virus 40. These observations make available in vitro models of virus-induced oncogenesis in astrocytes and provide simple techniques for obtaining astrocytoma cell lines suitable for screening studies of chemical agents effective against astrocytomas. PMID- 4307976 TI - Human granulocyte collagenase. AB - A collagenase, operative at neutral and alkaline pH, has been extracted from the granule fraction of human granulocytic leukocytes. It digests reconstituted collagen fibrils and reduces the viscosity of collagen solutions. Cleavage of collagen in solution with purified enzyme produces the discrete products characteristic of other animal collagenases. PMID- 4307978 TI - [Malignant hemopathy of the aplastic kind with important nuclear anomalies of granulocytes]. PMID- 4307979 TI - [The passive hemagglutintion reaction in pertussis]. PMID- 4307977 TI - [Prolonged neonatal jaundice due to breast feeding]. PMID- 4307980 TI - [A comparative study of the soluble antigens of the parapertussis and pertussis microbes]. PMID- 4307981 TI - The regulation of ACTH secretion. PMID- 4307982 TI - Production of circulating interferon in the bovine species. PMID- 4307983 TI - Interferon induction in the bovine species by infectious bovine rhinotracheitis virus. PMID- 4307984 TI - Serologic comparisons of infectious canine hepatitis and toronto A26-61 canine adenoviruses. PMID- 4307985 TI - Characteristics of in vitro infection of chicken kidney cell cultures with a herpesvirus from Marek's disease. PMID- 4307986 TI - Susceptibility of cultured mammalian cells to infection with a herpesvirus from Marek's disease and T-virus from reticuloendotheliosis of chickens. PMID- 4307987 TI - Effect of polysorbate 80 and ether on hemagglutination titers of certain myxoviruses. PMID- 4307988 TI - Pyrophosphate as a selective inhibitor of macromolecule synthesis in normal and leukemic leukocytes. PMID- 4307989 TI - Effect of quercetin on membrane-linked activities. PMID- 4307990 TI - 2,4-dinitro-5-ethyleneiminobenzamide (CB 1954): a potent and selective inhibitor of the growth of the Walker carcinoma 256. PMID- 4307991 TI - Kinetic studies of the mechanism of S-adenosylmethionine synthetase from yeast. PMID- 4307992 TI - The action of staphylococcal nuclease on synthetic substrates. PMID- 4307993 TI - Analogs of inosine 5'-phosphate with phosphorus-nitrogen and phosphorus-sulfur bonds. Binding and kinetic studies with inosine 5'-phosphate dehydrogenase. PMID- 4307994 TI - Metabolic control and structure of glycolytic enzymes. 8. Reversal of the dissociation of rabbit muscle pyruvate kinase into unfolded subunits. PMID- 4307995 TI - The stoichiometry and site specificity of the uncoupling of mitochondrial oxidative phosphorylation by salicylanilide derivatives. PMID- 4307996 TI - Comparative studies on the carbohydrate-containing membrane components of normal and virus-transformed mouse fibroblasts. I. Glucosamine-labeling patterns in 3T3, spontaneously transformed 3T3, and SV-40-transformed 3T3 cells. PMID- 4307997 TI - Comparative studies on the carbohydrate-containing membrane components of normal and virus-transformed mouse fibroblasts. II. Separation of glycoproteins and glycopeptides by sephadex chromatography. PMID- 4307999 TI - Catalytic mechanism of pig heart mitochondrial malate dehydrogenase studied by kinetics at equilibrium. PMID- 4307998 TI - Isolation of rat liver mitochondrial membrane fractions and localization of the phospholipase A. PMID- 4308000 TI - Spin-labeled hemoglobin derivatives in solution, polycrystalline suspensions, and single crystals. PMID- 4308001 TI - A mannose- and erythritol-containing glycolipid from Ustilago maydis. PMID- 4308002 TI - Chemistry and metabolism of sphingolipids. Chemical synthesis of 2-amino-1 hydroxyoctadecan-3-one (3-ketosphinganine). PMID- 4308003 TI - The mechanism of action of ethanolamine deaminase. V. The photolysis of enzyme bound alkylcobalamins. PMID- 4308004 TI - Inhibition of glutamine synthetase by methionine sulfoximine. Studies on methionine sulfoximine phosphate. PMID- 4308005 TI - [Lipids of resting skeletal muscle of rats]. PMID- 4308006 TI - [Incubation of 3H-6,7-estrone in the presence of rat and rabbit liver slices]. PMID- 4308007 TI - [Lowering of intracellular levels of ATP and formation of excess porphyrins in white rats]. PMID- 4308008 TI - [Study of the mechanism of loss of sensitivity to the protective action of exogenous interferon in cells infected by murine sarcoma virus]. PMID- 4308012 TI - Precipitin response of cattle to bovine papilloma virus. PMID- 4308009 TI - Effect of chemical carcinogens on virus-induced Rous sarcoma. PMID- 4308014 TI - [Riedel's lobe of the liver]. PMID- 4308011 TI - The oncogenic effects of nontransforming viruses from avian myeloblastosis virus. PMID- 4308013 TI - Hexokinase isozyme patterns of experimental hepatomas of rats. PMID- 4308010 TI - Ribonucleotide reductase activity in cell-free extracts of Yaba poxvirus tumor and normal monkey tissues. PMID- 4308015 TI - Excitability changes in interneurons of an epileptic focus during the development of tonic seizures. PMID- 4308016 TI - Acetylcholine release from motor-nerve endings in rats treated with neostigmine. PMID- 4308017 TI - The presence of inhibitory nerves in the colon after sympathetic denervation. PMID- 4308018 TI - Studies on DNA methylase activity in mammalian tissue. PMID- 4308019 TI - Cytochrome oxidase activity in different hypothalamic areas. Influence of castration. PMID- 4308020 TI - Analysis of the convulsant action of pentylenetetrazol. PMID- 4308021 TI - IgG as the main immobilization factor in rabbit antiserum against Entamoeba. PMID- 4308022 TI - Effects of chronic melatonin and saline injections on pituitary adrenal secretion. PMID- 4308023 TI - The duration of action of the synthetic pentacosapeptide D-serine-1-norleucine-4 valinamide-25-beta-1-25-corticotrophin (DW-75) in man. PMID- 4308024 TI - [The place of scintiphotography in physiopathologic studies]. PMID- 4308025 TI - Synthesis of NAD and catabolism of nicotinic acid in the isolated perfused liver of normal and X-irradiated rat. PMID- 4308026 TI - Electron transport system of the protoheme-requiring anaerobe Bacteroides melaninogenicus. AB - Protoheme is essential for the growth of some strains of Bacteroides melaninogenicus. At low concentrations in the growth medium, protoheme determines the doubling time, total cell yield, and amount of cytochrome per bacterium. At high protoheme concentrations, the doubling time, total cell yield, and amount of enzymatically reducible cytochrome appear to remain nearly constant, and protoheme is accumulated by the cell. The accumulated protoheme can support the growth of the bacterium for at least eight generations in a protoheme-free medium. When growth and cytochrome content are proportional during growth at low protoheme concentrations, the bacteria incorporate 10 to 20% of the total available protoheme into a membrane-bound respiratory system. This respiratory system includes cytochrome c, a carbon monoxide-binding pigment, and possibly flavoproteins. The pigments can be reversibly reduced by reduced nicotinamide adenine dinucleotide or endogenous metabolism and can be oxidized anaerobically by fumarate or by shaking in air. Electron transport is inhibited by 2-n-nonyl-4 hydroxy-quinoline-N-oxide. PMID- 4308027 TI - Disposition of neurotransmitters in experimental mouse glioma. PMID- 4308028 TI - Mitochondrial alterations in the spinal ganglion cells of the rat accompanying the long-lasting sensory disturbance induced by capsaicin. PMID- 4308030 TI - [Experience in the transplantation of corneas dehydrated with silicagel]. PMID- 4308029 TI - Enzymatic degradation of diazinon by rat liver microsomes. PMID- 4308031 TI - Some current problems in infections of the skin with the virus of herpes simplex and varicella-zoster. PMID- 4308033 TI - [Neurologic complications in the patients with diabetes]. PMID- 4308032 TI - [Operative therapy of lung metastases]. PMID- 4308035 TI - Corticosteroidogenic effect of long-acting beta 1-24corticotrophin (CIBA 42.915 BA). PMID- 4308034 TI - [A method of determining anticollagenase in antihistolyticus sera]. PMID- 4308036 TI - Intestinal Clostridium perfringens in rheumatoid arthritis and other collagen diseases. PMID- 4308037 TI - Possible role of amygdala in regulation of gastric secretion in chronic fistula rats. PMID- 4308038 TI - Differential regulation of blood flow to red and white muscle in sleep and defense behavior. PMID- 4308039 TI - [Presence and separation of plant nucleotide glucose pyrophosphorylases]. PMID- 4308040 TI - [Synthesis and biological activity of thyroxine and adrenergic derivatives. XI. Site of action of thyroid hormones and their acetate metabolites on the respiratory chain]. PMID- 4308041 TI - [Determination, with periodate, of compounds subject to peroxidation. II. Cyclohexanepentols]. PMID- 4308042 TI - [Role of 3'-5'-monophosphate cyclic adenosine in the liberation of pituitary TSH]. PMID- 4308043 TI - [Electronic structure and tautometry of 8-azapurines]. PMID- 4308044 TI - [Ribonucleic acids and proteins from cells infected by mouse encephalomyocarditis virus (EMC) in the presence of pyronine]. PMID- 4308045 TI - [Double transformation of hamster cells by Rous and polyoma viruses]. PMID- 4308046 TI - Electrophysiological correlates of visual perceptual masking in monkeys. PMID- 4308047 TI - The rubrospinal tract. II. Facilitation of interneuronal transmission in reflex paths to motoneurones. PMID- 4308049 TI - [The hematopoietic system of the rat in chronic introduction of ammonium perchlorate into the stomach]. PMID- 4308050 TI - Control of cell multiplication in uninfected chicken cells and chicken cells converted by avian sarcoma viruses. PMID- 4308048 TI - [An experimental study of the pathogenicity of flour and grain dust]. PMID- 4308051 TI - Immunoreactive fragments of angiotensin II in blood. PMID- 4308052 TI - T-antigen and DNA synthesis in macrophages infected with polyoma virus. PMID- 4308053 TI - [Current data on cerebral edema. II. Therapeutical aspects]. PMID- 4308056 TI - The structure of the respiratory syncytial virus. PMID- 4308055 TI - Enhancement and inhibition of avian sarcoma viruses by polycations and polyanions. PMID- 4308057 TI - [Virological diagnosis of Herpes simplex virus infections]. PMID- 4308058 TI - [Experimental for achievement of therapeutic sera against respiratory infections from immunized donors]. PMID- 4308054 TI - Studies on mouse leukemia viruses. I. Isolation and characterization of a group specific antigen. PMID- 4308059 TI - [Significance of uropepsin test in hormonal and antibacterial therapy of patients with pulmonary tuberculosis]. PMID- 4308060 TI - Respiratory viruses. Report of a WHO scientific group. PMID- 4308061 TI - [Extraction of the soluble antigens of B. pertussis during cultivation in a fluid nutrient medium]. PMID- 4308062 TI - [The variability of individual properties of subcultures of Cl. perfringens type A grown from separate colonies of strain BP6K (28)]. PMID- 4308063 TI - [Extraction of a highly purified agglutinogen of B. pertussis]. PMID- 4308064 TI - Cytology of carcinoma of the trachea. PMID- 4308065 TI - Studies on hydrolytic enzyme activity in the connective tissue of the human periodontal ligament. Observations apart from areas of inflammation. PMID- 4308066 TI - Carcinoma in pleomorphic adenoma of the parotid gland. PMID- 4308067 TI - A clinical and metabolic study of masculinizing arrhenoblastoma. PMID- 4308068 TI - Brenner's tumor with theca cell luteinization and hormonal function. PMID- 4308069 TI - Free radicals from biological purines and pyrimidines. PMID- 4308070 TI - Charge-transfer complexes in biological systems. PMID- 4308071 TI - Electronic structure of iron in porphyrin complexes. PMID- 4308072 TI - Electron-nuclear and electron-electron spin interactions in the study of enzyme structure and function. PMID- 4308073 TI - Tyrosine fluorescence in proteins. PMID- 4308074 TI - Electronic structures and spectra of flavins: an improved Pariser-Parr-Pople Mo and semiempirical unrestricted Hartree-Fock computations. PMID- 4308075 TI - A proposed mechanism for subunit interaction in hemoglobin. PMID- 4308076 TI - [Possible adverse effects of the antibiotic treatment of infant enteritis]. PMID- 4308077 TI - [Clinical course of salaam convulsions in enzygotic twins]. PMID- 4308078 TI - Enzyme envelopes on colloidal particles. PMID- 4308079 TI - In vitro production of 25-hydroxycholecalciferol. PMID- 4308080 TI - Induction of respiratory control by K+ in mitochondria. PMID- 4308081 TI - A cyclic AMP--stimulated protein kinase in adipose tissue. PMID- 4308083 TI - Cytological evidence for the long "quiescent" stage of gastric cancer in 2 patients with pernicious anemia. PMID- 4308082 TI - Tricholemmoma. PMID- 4308085 TI - [Breast neoplasms]. PMID- 4308084 TI - [Comparative contribution to the structure and metabolism of the myocardium and of red or white muscle]. PMID- 4308086 TI - [Lactate dehydrogenase of the crayfish Oronectes limosus. Isolation and characterization]. PMID- 4308087 TI - [Isolation of cell organelle fractions from rat liver by means of continuous carrier-free electrophoresis]. PMID- 4308088 TI - Antibody pattern against polioviruses in healthy adult population of Lucknow (India). PMID- 4308089 TI - Tarsal tunnel syndrome. PMID- 4308090 TI - Tumor board proceedings. PMID- 4308091 TI - Application of magnesium silicate adsorption chromatography to the determination of mephobarbital and diphenylhydantoin in tablets. PMID- 4308092 TI - Diet and dental caries. The phosphate sequestration hypothesis. PMID- 4308093 TI - [On the Synacthen screening test]. PMID- 4308094 TI - Incorporation of 14C-tryptophan into 14C-protein by cultured rat pineals: stimulation by l-norepinephrine. AB - Organ cultures of individual rat pineals incorporate (14)C-tryptophan into proteins at a nearly constant rate for at least 48 hours. Previous studies have shown that these cultures also convert (14)C-tryptophan to serotonin, melatonin, and 5-hydroxyindoleacetic acid, and release these indoles into the media. The formation of (14)C-protein from (14)C-tryptophan is accelerated by the addition to the culture medium of l-norepinephrine or related catecholamines but is not modified by serotonin, melatonin, or 5-hydroxyindoleacetic acid. One mechanism by which norepinephrine stimulates the synthesis of (14)C-protein from (14)C tryptophan involves increasing the uptake of the (14)C-tryptophan into pineal parenchymal cells, inasmuch as (1) norepinephrine increases the intracellular content of (14)C-tryptophan as well as its conversion to its major products, (14)C-protein and (14)C-indoles; (2) norepinephrine does not stimulate (14)C protein synthesis in pineal organs which contain a previously fixed amount of (14)C-tryptophan; and (3) norepinephrine does not stimulate (14)C-protein synthesis from (14)C-methionine or (14)C-leucine. The finding that norepinephrine, but not serotonin, can stimulate the incorporation of (14)C tryptophan into pineal proteins is consistent with the hypothesis that norepinephrine is the neurotransmitter substance utilized by pineal sympathetic nerve endings. PMID- 4308095 TI - The use of an ethidium analogue in the dye-buoyant density procedure for the isolation of closed circular DNA: the variation of the superhelix density of mitochondrial DNA. AB - The separation between open and closed circular DNA in buoyant CsCl gradients containing intercalating dyes depends on the superhelix density of the closed form. These separations are about 1.8 times larger with propidium iodide than with ethidium bromide. The superhelix densities of mitochondrial DNA from HeLa cells and Lytechinus pictus eggs appear to be about two thirds that of mitochondrial DNA from rat and rabbit liver. PMID- 4308096 TI - The isolation of two enzyme-ribonucleic acid complexes involved in the synthesis of foot-and-mouth disease virus ribonucleic acid. AB - The foot-and-mouth disease virus-RNA polymerase complex was released from membrane particulates present in the cytoplasm of infected baby hamster kidney cells. The soluble polymerase complex was fractionated by zonal centrifugation in sucrose gradients. Two polymerase complexes (RNA and protein complex) active in the cell-free system were isolated and had S-rate ranges of 20-70S and 100-300S, respectively. The light polymerase complex contained 20S double-stranded RNA; and the heavy polymerase complex contained a polydisperse, partially RNase-resistant RNA. The cell-free product of these two polymerase complexes was analyzed by zonal centrifugation in sucrose gradients. The light polymerase complex synthesized only 20S double-stranded RNA. The product of the heavy polymerase complex contained no detectable 20S double-stranded RNA and only a peak of single stranded RNA with S-rate corresponding to 37S viral RNA. A third polymerase complex was isolated with S-rate greater than 300S, and it contained a polydisperse, partially RNase-resistant RNA. This third polymerase complex synthesized both 37S viral RNA and 20S double-stranded RNA in the cell-free system, and it is probably the native polymerase complex still bound to cellular particulates. PMID- 4308097 TI - A quantitative comparison of formation of spontaneous and virus-produced viable hybrids. AB - Ultraviolet-inactivated Sendai virus used in conjunction with a selective system reproducibly gives high yields of viable hybrid cell lines. With two different crosses, the frequency of hybrid colonies obtained after virus treatment was found to be 100 times greater than the frequency of spontaneous hybrids, and this increase was found to show little variation between 33 and 1000 hemagglutinating units of virus. No differences have been found between the properties of hybrids obtained after Sendai treatment and those obtained from untreated mixed cultures of parental cells. PMID- 4308098 TI - Cytochrome oxidase deficiency in Wilson's disease: a suggested ceruloplasmin function. AB - The hypothesis is advanced that ceruloplasmin functions in enzymatic transfer of copper to copper-containing enzymes, such as cytochrome oxidase. To test this hypothesis, leucocytes from Wilson's disease patients, heterozygous carriers, and normal subjects were assayed for cytochrome-oxidase activity. The data reported here show markedly reduced levels of activity in Wilson's disease cases and moderate reductions in heterozygous individuals relative to normal controls. These observations and a close correlation between the level of cytochrome oxidase activity in the leucocytes and ceruloplasmin in the serum tend to support the hypothesis. PMID- 4308099 TI - Differences in the transfer RNA's of normal liver and Novikoff hepatoma. AB - -A comparison of the elution profiles of 18 aminoacyl-tRNA's from Novikoff hepatoma with those from normal liver on a methylated albuminkieselguhr column revealed the occurrence of new species of tRNA for histidine, tyrosine, and asparagine in the hepatoma. In addition, the hepatoma tRNA's for arginine, isoleucine, lysine, methionine, serine, alanine, and tryptophan eluted at a higher salt concentration than the corresponding tRNA's of normal liver. The remaining eight amino acids did not show any significant differences in the elution profiles. PMID- 4308100 TI - A difference in the architecture of the surface membrane of normal and virally transformed cells. AB - Several tissue culture cell lines that were transformed by a tumor virus have been found to react with an agglutinin, while under identical conditions their untransformed parent cell lines did not agglutinate. Since a short treatment of the parent cell line with low concentrations of proteases exposed the same agglutinin receptor sites in a fashion indistinguishable from the transformed cells, it is proposed that both viral and chemical transformation produce changes in the architecture of the membrane, identical to those of the proteases. PMID- 4308101 TI - Scintillation camera scanning of the salivary glands. PMID- 4308102 TI - [Homotransplantation of tissue cultures]. PMID- 4308103 TI - [Anatomo-clinical considerations on breast tumors of the phyllodes type]. PMID- 4308104 TI - [The central nervous apparatus for regulation of osmosis]. PMID- 4308105 TI - [Experimental adrenocortical hemorrhage in anticoagulated rats induced by stimulating the adrenal cortex]. PMID- 4308106 TI - [Induction of brain and spinal cord tumors in rabbits with N-methyl-N nitrosourea]. PMID- 4308107 TI - [Cancerization of the rat intestine by 1,2-dimethylhydrazine]. PMID- 4308108 TI - [Determination of the water binding capacity of enzymaticly damaged cartilage and the influence of Rumalon]. PMID- 4308109 TI - Histochemistry of the neuromuscular spindles in the chicken during development. PMID- 4308110 TI - [On the problem of arrhenoblastoma of the ovary]. PMID- 4308111 TI - [Immunologic characterization of sarcomas artificially infected with Graffi leukemia virus. II. Studies on the differentiation between viral and new cellular antigens]. PMID- 4308112 TI - [On the immunologic sensitizability of tumor patients]. PMID- 4308113 TI - [On the problem of quantitative determination of experimental hepatomas using Au198 colloid]. PMID- 4308114 TI - [On a new Soviet method of intracapsular cataract extraction by the use of silica gel]. PMID- 4308115 TI - [Acute pneumonia caused by Bacillus pyocyaneus]. PMID- 4308116 TI - [Morphologic changes in experimental berylliosis of the lungs during treatment with aminoalkylpolyphosphinous acids (phosphororganic complexones)]. PMID- 4308117 TI - [Evaluation of rehabilitation prospects in schizophrenics]. PMID- 4308119 TI - Control of cholesterol synthesis in hepatomas: the effect of bile salts. PMID- 4308118 TI - Occurrence and nature of O-alkyl and O-alk-I-enyl moieties of glycerol in lipids of Morris transplanted hepatomas and normal rat liver. PMID- 4308120 TI - Enzymatic synthesis of lycopene from [4-14C]isopentenyl pyrophosphate. PMID- 4308121 TI - Hydrolysis of steroid phosphates by mouse tissue phosphatases. PMID- 4308123 TI - [Action of ACTH, hydrocortisone and prednisolone on human erythrocytic angiotensinase in vitro]. PMID- 4308122 TI - [Effect of epinephrine on the state of oxidoreduction of NAD in the dog]. PMID- 4308124 TI - [Action of oxytocin on human erythrocytic angiotensinase in vitro]. PMID- 4308125 TI - [Action of parathormone on human erythrocytic angiotensinase in vitro]. PMID- 4308127 TI - [Action of various pH values of human erythrocytic angiotensinase in vitro]. PMID- 4308126 TI - [Protease inhibitors (trasylol and epsilon-aminocaproic acid) on human erythrocytic angiotensinase]. PMID- 4308129 TI - [Comparison of beta 1-24-ACTH and DW-75 for induction of sexual excitation in the rabbit by intraventricular injection]. PMID- 4308128 TI - [Influence of prednisolone on sexual excitation induced in the rabbit by intraventricular injection of beta 1-24-ACTH]. PMID- 4308130 TI - [Effect of aminophylline introduced into the lateral ventricles on sexual stimulation induced in the rabbit by intraventricular injection of beta-1-24 ACTH]. PMID- 4308131 TI - [Preparation and properties of reduced alpha-NAD]. PMID- 4308133 TI - Serological properties of bacterial fractions of the Clostridium perfringens type A strains causing acute food poisonings. PMID- 4308132 TI - X-amidinotransferase in viomycin biosynthesis. PMID- 4308134 TI - [A rare case of multifocal and multiform tumor of salivary gland type]. PMID- 4308135 TI - A possible role for cyclic AMP in gibberellic acid triggered release of alpha amylase in barley endosperm slices. PMID- 4308136 TI - Potentiation of cutaneous inhibition by alcohol. PMID- 4308137 TI - [Morphologic changes in the extraorbital gland of white rats following nutritional copper deficiency]. PMID- 4308138 TI - [Intradermoreaction with inactivated herpes virus. I. Analysis of the factors influencing the reaction]. PMID- 4308139 TI - [Contribution to the study of Pautrier and Woringer lipomelanic reticulosis]. PMID- 4308140 TI - Phosphatases of "Tetrahymena pyriformis". PMID- 4308142 TI - [Tumors of the upper cervical spinal cord]. PMID- 4308141 TI - [State of several hydrolytic enzymes of the vascular wall in arteriosclerosis in men]. PMID- 4308143 TI - [Wilms' tumor in geriatrics]. PMID- 4308145 TI - [Mouth ulcers in general medicine, with a special study of herpetic and herpetiform injuries]. PMID- 4308144 TI - [Micropuncture study of the clamped kidney in unilaterally nephrectomized rats with experimental renal hypertension]. PMID- 4308147 TI - [Ophthalmologic diagnostic possibilities in diseases of the central nervous system]. PMID- 4308146 TI - [Studies on hypophosphatasia]. PMID- 4308148 TI - [Immunity in cattle produced by anti-foot-and-mouth disease vaccines derived from cultured virus]. PMID- 4308149 TI - [The treatment of climacteric complaints with Ovaribran in gynecological practice]. PMID- 4308150 TI - [Diagnostic and therapeutic hints of small peripheral neurology in the everyday medical practice]. PMID- 4308151 TI - [Local lesions of peripheral nerves. Diagnostic and therapeutic aspects]. PMID- 4308152 TI - [Histometric studies of the adrenal glands in rats. The effect of ACTH administration, formalin stress, hypophysectomy and cortisone treatment on the adrenal gland zones]. PMID- 4308153 TI - [Histological study of the morphokinesis of the adrenal cortex]. PMID- 4308156 TI - Some implications of the sleep patterns of pregnancy for postpartum emotional disturbances. PMID- 4308155 TI - The physiological maturity of adolescent psychiatric patients, juvenile delinquents and normal teenagers. PMID- 4308154 TI - [Methods for bacteriological testing of fresh cheeses and yogurts]. PMID- 4308157 TI - [Action of periodic acid on some isoquinolines at the alcoholic or ketonic functional group]. PMID- 4308158 TI - [Role of the adrenal glands in lowering plasma renin associated with an increase in angiotensin]. PMID- 4308159 TI - In vitro and in vivo virostatic properties of alkylated pyrimidines against DNA and RNA viruses. PMID- 4308160 TI - A preliminary note on a recent increase in the incidence of hepatoma in the West Nile District of Uganda. PMID- 4308161 TI - Acute effects of various gonadotropins and other pituitary hormones on preovulatory ovarian progestin secretion in hypophysectomized rats. PMID- 4308162 TI - [On the development of the rat small intestine. Morphologic, histochemical and experimental studies]. PMID- 4308163 TI - Dianemycin, an antibiotic of the group affecting ion transport. PMID- 4308164 TI - Metabolism of cyclic adenosine 3',5'-monophosphate-8-14C by isolated, perfused rat liver. PMID- 4308165 TI - The inhibition by physiological orthophosphate concentrations of hydrolytic and synthetic activities of liver glucose 6-phosphatase. PMID- 4308166 TI - Control of gluconeogenesis in liver. IV. Differential effects of fatty acids and glucagon on ketogenesis and gluconeogenesis in the perfused rat liver. PMID- 4308167 TI - Membranes of animal cells. IV. Lipids of the L cell and its surface membrane. PMID- 4308168 TI - Some properties of an apoceruloplasmin-like protein in human serum. PMID- 4308169 TI - A neurotoxin, toxin alpha, from Egyptian cobra (Naja haje haje) venom. I. Purification, properties, and complete amino acid sequence. PMID- 4308170 TI - Anaerobic oxidation-reduction titrations of fungal laccase. Evidence for several high potential electron-accepting sites. PMID- 4308171 TI - Reduced 1,6-dihydrodiphosphopyridine nucleotide. Chemical properties and enzymatic modification. PMID- 4308172 TI - Studies on the activation of phosphorylase in skeletal muscle by contraction and by epinephrine. PMID- 4308174 TI - Steroidogenesis in a case of hydatidiform mole. PMID- 4308173 TI - Ketogenesis and cholesterol synthesis in normal and neoplastic tissues of the rat. PMID- 4308175 TI - Micro-determination of corticosteroids in ovine peripheral plasma: effects of venipuncture, corticotrophin, insulin and glucose. PMID- 4308176 TI - Management of craniopharyngioma in childhood. PMID- 4308177 TI - The use of radiofibrinogen in the evaluation of the cold areas of the hepatic scans. PMID- 4308178 TI - Excess dietary zinc for the maternal rat, and zinc, iron, copper, calcium, and magnesium content and enzyme activity in maternal and fetal tissues. PMID- 4308180 TI - [Esophageal leukoplasia in liver cirrhosis]. PMID- 4308179 TI - Lipolytic action of serotonin in brown adipose tissue in vitro. PMID- 4308181 TI - [Esophageal necrosis of vascular origin]. PMID- 4308182 TI - [Infectious mononucleosis with pulmonary, pleural and mediastinal involvement]. PMID- 4308184 TI - [Superior mesenteric arteriography and hemorrhagic tumors of the small intestine]. PMID- 4308183 TI - [Crohn's disease revealed by a vesico-intestinal fistula and associated with a carcinoid tumour of the small intestine]. PMID- 4308185 TI - [Mental disorders of General Junot, Duke of of Abrantes]. PMID- 4308187 TI - [Serological properties of a virus isolated from the feces of healthy swine]. PMID- 4308186 TI - Renin-like pressor material in ovarian venous blood of pregnant rabbits. PMID- 4308188 TI - [The influence of the thyroid gland state on enzyme activity of glycogen metabolism of the rat skeletal muscles]. PMID- 4308189 TI - Herpes simplex virus infection detected on routine gynecologic cell specimens. PMID- 4308190 TI - Reversed action of acetylated corticotrophin: inhibition of adreno-cortical secretion. PMID- 4308191 TI - Effect of epinephrine on glucose metabolism in Novikoff ascites hepatoma cells. PMID- 4308193 TI - Occurrence of encephalitis caused by infectious bovine rhinotracheitis virus in calves in hungary. PMID- 4308192 TI - Oestrogen treatment in Cushing's syndrome. PMID- 4308194 TI - Occurrence of influenza A-equi-2 infection of horses in hungary. PMID- 4308196 TI - [Management of children with surgically treated scoliosis at the service for handicapped]. PMID- 4308195 TI - [Pains in diseases and injuries of the peripheral nerves]. PMID- 4308197 TI - [Treatment and follow up care of Bechterew patients]. PMID- 4308198 TI - [Changes in the sleep-waking cycle induced by brain-stem "split" in cats: anatomo functional correlations]. PMID- 4308199 TI - [On interference in the field of enteroviruses]. PMID- 4308200 TI - [Incorporation of choline in cells infected with poliovirus]. PMID- 4308201 TI - [Antipoliomyelitic activity in vitro of amino acids and oligopeptides]. PMID- 4308202 TI - [Further research on the development of poliovirus in "mixed" cultures in presence of guanidine]. PMID- 4308203 TI - [Effect of guanidine antagonists on development of guanidine-dependent viruses]. PMID- 4308204 TI - [State of oxido-reduction of NAD in vivo in the adrenalectomized and medullectomized rat]. PMID- 4308206 TI - [Protection by interferon of human embryo cells against infection by cytomegalic virus]. PMID- 4308205 TI - [Influence of protein-glycan interactions on the hydration potential of corneal stroma]. PMID- 4308207 TI - [Concentration of aphthous stomatitis virus by polyethylene glycol]. PMID- 4308208 TI - [Appearance and persistance of a specific repressor in Syrian hamster cells infected by polyoma virus]. PMID- 4308209 TI - [Clear cell hidradenoma (a contribution to histogenesis)]. PMID- 4308210 TI - [Clinical course of prostatic carcinoma]. PMID- 4308211 TI - [Cardiomechanics and sphygmographic indices after injection of phentolamine in subjects with hypertension induced by angiotensin II. Polygraphic study]. PMID- 4308213 TI - [Elimination of antibiotics and sulfonamides from the human organism during renal insufficiency and the therapeutic consequences]. PMID- 4308212 TI - [Influence of coenzyme A, nicotinamide adenine dinucleotide (NAD), alpha-lipoic acid and cocarboxylase on acute hepatitis (double blind experiment)]. PMID- 4308215 TI - [On the indices for intraabdominal resection of the rectum in cancer]. PMID- 4308217 TI - [Osteolysis of the mandibular angle and its causal-pathogenetic significance for radiculopathies due to intervertebral disk displacement]. PMID- 4308216 TI - [Synthetic analogs of corticotropin. Changes in the N-terminal amino group of the corticotropin-(1-23)-tricosipeptide-amide]. PMID- 4308214 TI - Gingival hyperplasia related to treatment with diphenylhydantoin (diphedan; DH). PMID- 4308218 TI - [Aeromonas hydrophila as a pyrogenic agent]. PMID- 4308220 TI - [Skeletal maturation in Mediterranean anemia]. PMID- 4308219 TI - [Results of 5 years of treatment of mesodermal mixed tumors and carcinosarcomas of the uterus]. PMID- 4308221 TI - [Findings and considerations on 118 cases of reticulohistiocytomas in different sites]. PMID- 4308222 TI - [Hypoglycemia-inducing tumors of the pancreas]. PMID- 4308223 TI - [Emergency treatment of gastric burns caused by ingestion of strong acids: an experimental study]. PMID- 4308224 TI - [Waldenstrom's disease and amyloidosis. (Apropos of an anatomo-clinical case)]. PMID- 4308225 TI - [Diffuse interstitial pulmonary fibrosis revealing a pure visceral form of scleroderma. Clinical and anatomical study]. PMID- 4308226 TI - [Practical advice on the procedure to follow during intravenous cholangiography]. PMID- 4308227 TI - [Resuscitation of the newborn]. PMID- 4308228 TI - [Treatment of Basedow hyperthyroidism by protracted doses of radioactive iodine]. PMID- 4308229 TI - [Role of hormones in magnesium metabolism]. PMID- 4308230 TI - [Broncho-pulmonary mycoses]. PMID- 4308231 TI - [Subacute polyarthritis in adults]. PMID- 4308232 TI - [Study of the preservation of samples of plasma and serum intended for biological analysis]. PMID- 4308233 TI - [Value of a dietary milk for infants in tube feeding]. PMID- 4308234 TI - [Importance of the angiotensin perfusion for the diagnosis of renovascular diseases]. PMID- 4308235 TI - [Luteinization and corpus luteum formation (comparative studies with findings in animals)]. PMID- 4308236 TI - [Immediate results of surgery of primary lung cancer]. PMID- 4308238 TI - [Neuromuscular block induced with procaine amide. (Electromyographic study)]. PMID- 4308237 TI - [X-ray diagnosis of breast cancer]. PMID- 4308239 TI - [Brief considerations on complications of local anesthetics. (Apropos of 3 treated cases)]. PMID- 4308240 TI - Epinephro-phlebography of benign tumours. PMID- 4308241 TI - Scintigraphy and angiography in demonstration of hepatic tumours. PMID- 4308242 TI - Tumor extent as a determining factor in radiotherapy of glioblastomas. PMID- 4308244 TI - [Complementary endocrine treatment of cerebral tumors]. PMID- 4308243 TI - [Irradiation of glioblastoma multiforme. Results with respect to conventional radiotherapy and gamma therapy apropos of 87 cases]. PMID- 4308245 TI - [Radiotherapy of glioblastomas in adults and children]. PMID- 4308247 TI - Biology and morphology of glioblastoma multiforme. PMID- 4308246 TI - [The intracellular protracted long term radiation treatment of pituitary adenoma by means of stereotaxic implantation of iridium 192]. PMID- 4308248 TI - [Gamma-encephalography. Possibilities and limitations in the diagnosis of the presence and extension of glioblastomas]. PMID- 4308250 TI - [Medical treatment of child and adolescent bronchiectasis. (Experience in a specialized climatic center)]. PMID- 4308249 TI - Roentgen sensitivity of cerebral tumours and so-called late irradiation necrosis of the brain. PMID- 4308251 TI - Haemodynamic studies in calves sustained on artificial hearts. PMID- 4308252 TI - Primary signet ring cell carcinoma of the urinary bladder. Report of two cases. PMID- 4308254 TI - [Importance of regional circulation for treatment of cardiogenic shock]. PMID- 4308253 TI - [Significance of catabolic processes in cartilage and their connections to the pathogenesis of degenerative joint diseases. Experimental studies]. PMID- 4308255 TI - [Effects of angiotensin II on the renal function in healthy men in conditions of urinary hypertonicity]. PMID- 4308256 TI - [Effects of angiotensin II on renal function in healthy men in conditions of urinary hypotonicity]. PMID- 4308258 TI - The role of biochemical and neurohumoral factors in the laboratory evaluation of antiepileptic drugs. PMID- 4308257 TI - [On the problem of wound healing]. PMID- 4308260 TI - Effects of anticonvulsant drugs on nerve terminals. PMID- 4308259 TI - The developing animal as a model. PMID- 4308261 TI - Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs. PMID- 4308262 TI - The relationship of optic nerve fiber groups activated by electrical stimulation to the consequent central postsynaptic events. PMID- 4308263 TI - Extraocular muscle intracellular and motor nerve responses to semicircular canal stimulation. PMID- 4308264 TI - An examination of variability of blood chemistry, hematology, and proteins, in relation to age. PMID- 4308265 TI - [On the problems of sleep]. PMID- 4308266 TI - [Paget's disease (report of a case in a male)]. PMID- 4308267 TI - [The use of a deposit of ACTH in the pathology of acute rheumatism (findings in 30 patients)]. PMID- 4308268 TI - Nephroblastoma in a cat: the effects of nephrectomy and occlusion of the caudal vena cava. PMID- 4308269 TI - [On congenital cytomegaly. A clinical case contribtuion]. PMID- 4308270 TI - [2 cases of cytomegaly in an Indian village]. PMID- 4308271 TI - Mosquito control activities of the U.S. armed forces in the republic of Vietnam. PMID- 4308272 TI - Rapid transformation of cells by Rous sarcoma virus. AB - The conditions for synchronous transformation of chick embryo cells by infection with Rous sarcoma virus are studied. Two factors, the treatment of cells with DEAE-dextran and the use of cells which grow rapidly following virus infection, are found to be most important. Under the conditions described, the Schmidt Ruppin strain of Rous sarcoma virus at a multiplicity of higher than 5 induces morphological alteration in about 90 per cent of the cell population within 24 hours after infection. The alteration in the morphology is accompanied by acquisition of the ability of cells to grow in agar medium and by the increased rate of incorporation of thymidine and uridine into nucleic acids. PMID- 4308273 TI - Adenyl cyclase and hormone action. I. Effects of adrenocorticotropic hormone, glucagon, and epinephrine on the plasma membrane of rat fat cells. AB - A large number of hormones, of diverse molecular structure, evoke characteristic responses in target cells via the intermediary 3',5'-AMP, the specificity of hormone action upon cell type being achieved by selective stimulation of adenyl cyclase. In the fat cells of rat adipose tissue, adenyl cyclase is stimulated by a number of hormones of disparate molecular structure, posing the question whether this cell type posesses multiple cyclase systems with distinctive specificities for individual hormones, or a single cyclase with broad specificity to a variety of hormones. Studies of the stimulatory effects of adenocorticotropin, glucagon, and epinephrine upon the adenyl cyclase of the rat fat cell "ghosts" (plasma membrane sacs) have shown that distinctive selectivity sites for each of these hormones can be differentiated. The beta-adrenergic blocking agent Ko 592 abolished the stimulatory effect of epinephrine without influencing adenocorticotropin or glucagon; Ca was required for adenocorticotropin action, but not for glucagon or epinephrine. Dose-response curves show that the affinity of hormones to the cyclase system was in the order: glucagon > adenocorticotropin >> epinephrine; the magnitude of cyclase activation by maximal doses of hormones had a reversed order. Combinations of maximal doses of hormones failed to produce additive stimulation. The results show that in the membrane of the fat cell a single catalytic unit of adenyl cyclase is coupled to distinctive selectivity sites for three lipolytic hormones. PMID- 4308275 TI - Vitamin D3-stimulated template activity of chromatin from rat intestine. AB - Administration of vitamin D to rats deficient in this vitamin markedly increases the template activity for DNA-dependent RNA synthesis by rat intestinal mucosal chromatin. The maximum stimulation of template activity occurs three hours after a dose of 2000 international units of vitamin D(3) is given. These results support the concept that vitamin D functions by initiating the transcription of DNA into mRNA, which codes for functional protein(s) involved in calcium transport in the small intestine. PMID- 4308274 TI - On the mechanism of action of adrenocorticotropic hormone: the binding of cyclic 3',5'-adenosine monophosphate to an adrenal cortical protein. AB - The binding of cyclic 3',5'-adenosine monophosphate (cyclic AMP) within the adrenal cortical cell was studied. Cyclic AMP binds specifically to a protein which is associated predominantly with the microsomal fraction of the cell. The binding protein was purified approximately 100-fold. PMID- 4308276 TI - [Etiology and prevention of peripheral nerve lesions in the psychiatric clinic]. PMID- 4308278 TI - [True and false adverse effects of thymoanaleptic medications]. PMID- 4308280 TI - [Hepatic coma in cirrhosis]. PMID- 4308277 TI - [Prescription of corticotherapy on alternate days for long periods]. PMID- 4308279 TI - [Focal medionecrosis and its relationship with arteriosclerosis]. PMID- 4308281 TI - [Radiologic diagnosis of ovarian dermoid cysts]. PMID- 4308283 TI - Generation and survival of angiotensin in nonrefrigerated plasma. An explanation for presence of pressor material in human plasma protein solutions used clinically. PMID- 4308282 TI - [Comments on the treatment of solid tumors with 5-fluorouracil]. PMID- 4308285 TI - Metabolism of oestriol-3-sulphate-16-glucosiduronate in pregnant women. PMID- 4308284 TI - [A rare case of delayed, complete, and sporadic osteogenesis imperfecta]. PMID- 4308286 TI - Nuclear shape variations in the fascicular zone of the rat adrenal gland. I. Effect of corticotrophin. PMID- 4308287 TI - Corticosteroids in human blood. 3. Free and conjugated 17-hydroxycorticosteroids in healthy people and patients with Cushing's syndrome, before and after administration of corticotrophin. PMID- 4308288 TI - Chromophobe pituitary adenoma with acromegaly and TSH-induced hyperthyroidism associated with parathyroid adenoma. Acromegaly and parathyroid adenoma. PMID- 4308290 TI - Glycogen content of leukocytes of some animal species. PMID- 4308289 TI - Diagnosis of Cushing's syndrome. The differentiation between adrenocortical hyperplasia and adrenocrotical adenoma by means of lysine-vasopressin. PMID- 4308291 TI - [Derivatives of viomycin. V. Di(oxytetracyclinemethyl)viomycin and tri(oxytetracyclinemethyl)viomycin, preparation and properties]. PMID- 4308292 TI - Clearing-factor lipase in adipose tissue. Distinction of different states of the enzyme and the possible role of the fat cell in the maintenance of tissue activity. AB - 1. Incubation of intact epididymal adipose tissue from fed rats at 37 degrees in an albumin solution at pH7.4 in vitro results in rapid loss of clearing-factor lipase activity until a low activity, stable to prolonged incubation, is attained. The clearing-factor lipase activity of intact tissue from starved rats, which is initially much less than that of tissue from fed rats, is mainly stable to incubation at 37 degrees . 2. Much of the clearing-factor lipase activity of intact epididymal adipose tissue from fed rats is inactivated by collagenase. The enzyme activity of intact tissue from starved rats is not inactivated by collagenase. 3. The clearing-factor lipase activity of fat cells isolated from the epididymal adipose tissue of fed rats is stable to prolonged incubation at 37 degrees . It represents only a small proportion of the total activity of the intact tissue. In starved rats, the isolated fat cells contain a much higher proportion of the activity of the intact tissue. Their activity is also stable at 37 degrees . 4. Incubation of isolated fat cells in a serum-based medium leads to a progressive rise in clearing-factor lipase activity. Actinomycin increases the extent of this rise in activity. No rise in clearing-factor lipase activity occurs when stromal-vascular cells isolated from epididymal adipose tissue are incubated in the medium. 5. The findings indicate that less than 20% of the activity of intact adipose tissue from fed rats is retained when fat cells are isolated from the tissue by collagenase treatment. The activity that is lost could be that which normally functions in the uptake of triglyceride fatty acids by the tissue. PMID- 4308293 TI - An improved system for the separation of metabolites of isotopically labelled vitamin D3 on silicic acid columns. PMID- 4308294 TI - The adenosine triphosphate inhibition of the pyruvate kinase reaction and its dependence on the total magnesium ion concentration. AB - 1. The effects of ATP, PP(i) and EDTA on the skeletal-muscle pyruvate kinase reaction at various concentrations of magnesium (where ;magnesium' refers to total Mg(2+), both free and in the form of complexes) were investigated. The reaction rate was determined as the amount of pyruvate formed in a recorded time of incubation. 2. At 44mm-magnesium the K(m) values for ADP and phosphoenolpyruvate were unaltered by the presence of ATP up to 6.8mm in systems buffered with either tris-hydrochloric acid or glycylglycine-sodium hydroxide, but the K(m) values were different in these systems. The K(m) for one substrate was independent of the concentration of the second substrate. 3. At 10mm magnesium in the tris-hydrochloric acid system ATP inhibited the reaction competitively with respect to ADP and phosphoenolpyruvate. In the glycylglycine sodium hydroxide system the inhibition appeared to be non-competitive. At 10mm magnesium the K(m) values were lower than at 44mm-magnesium and dependent on the system used. 4. In the tris-hydrochloric acid system the reaction rate rose with increasing magnesium concentration up to a maximum at a concentration 10-20 times that of ADP. Further increase inhibited the reaction and at 44mm-magnesium the rate was 25-50% of its maximum. This inhibition paralleled that produced by increasing trimethylammonium chloride concentrations and was not due to a specific effect of the Mg(2+) ion. 5. In the presence of 6.8mm-ATP no reaction occurred below 4-6mm-magnesium, and further increase apparently abolished the inhibition as the reaction rate increased and became equal to those obtained in the absence of ATP at 10-25mm-magnesium. Further increase in magnesium concentration gave reaction rates that were slightly higher in the presence of ATP than in its absence. The maximal rate in the presence of ATP was distinctly lower than in its absence. When 6.8mm-PP(i) or 6.8mm-EDTA was present the variations in reaction rate with rising magnesium concentration were similar to that obtained in the presence of ATP below 6-8mm-magnesium but further increase in the magnesium concentration resulted in an increase in the rate up to a maximum comparable with that of the control. The effect of pure chelation was thus a displacement of the reaction maximum to higher magnesium concentrations without changing the maximal rate. When correction had been made for this effect, ATP gave inhibition at 44mm-magnesium that was competitive with respect to ADP (K(i) 2.1x10(-2)m). This degree of inhibition is far less than was reported earlier and its importance for the mechanism of the pyruvate kinase reaction is discussed. PMID- 4308295 TI - Effect of actinomycin D and guanidine on the formation of a ribonucleic acid polymerase induced by foot-and mouth-disease virus and on the replication of virus and viral ribonucleic acid. AB - The RNA-dependent RNA polymerase induced in baby-hamster kidney cells by infection with foot-and-mouth-disease virus can be detected as early as 60min. after infection, which is 60min. before viral RNA synthesis commences. The time at which the polymerase can first be detected coincides with the latest time at which actinomycin D (50mug./10(7) cells) or guanidine (1mg./10(7) cells) inhibits virus replication. However, by increasing the concentration of guanidine, viral replication can be inhibited later in the growth cycle, casting doubt on the validity of the hypothesis that guanidine acts specifically on the formation of the viral RNA polymerase. PMID- 4308296 TI - [Effect of pH on the activity of yeast glyceraldehyde-3-phosphate dehydrogenase]. PMID- 4308297 TI - [The purification and properties of uridine diphosphate glucose-4-epimerase from mung bean (Phaseolus aureus)]. PMID- 4308298 TI - [Studies on phospholipids in morphologically different areas of the central nervous system]. PMID- 4308299 TI - [Tumor lipids. An investigation of the phospholipids of the Jensen sarcoma]. PMID- 4308300 TI - [Adenosinetriphosphatase activity of nuclear envelopes and from the cells of rat liver, Zaigdel hepatoma of rats and Ehrlich ascites tumour of mice]. PMID- 4308301 TI - Virus antibody levels in multiple sclerosis. PMID- 4308302 TI - Mouse hepatitis virus (MHV3) infection in chronic murine schistosomiasis mansoni. PMID- 4308303 TI - The role of hemodynamic factors on urinary calcium and magnesium excretion. PMID- 4308304 TI - Urinary levels of testosterone and epitestosterone in Down's syndrome (mongolism). PMID- 4308305 TI - A simple method for separate determination of the main 17,21-dihydroxy-20 ketosteroids. PMID- 4308306 TI - Erythrocyte 2, 3-diphosphoglycerate mutase: an optical test in hemolysates. PMID- 4308307 TI - Implications and applications of emission and atomic absorption spectroscopy for biological problems. PMID- 4308308 TI - [Contralateral synkineses. Clinical and electromyographic studies in idiopathic and symptomatic form]. PMID- 4308310 TI - Collagenase in the cornea. PMID- 4308309 TI - Peptidase in the cornea. PMID- 4308311 TI - Transmission of mammary tumor virus by female GR mice: results of egg transplantation. PMID- 4308312 TI - Respiration and protein synthesis in Escherichia coli membrane-envelope fragments. I. Oxidative activities with soluble substrates. AB - This paper describes experiments conducted with membranous and soluble fractions obtained from Escherichia coli that had been grown on succinate, malate, or enriched glucose media. Oxidase and dehydrogenase activities were studied with the following substrates: nicotinamide adenine dinucleotide, reduced form (NADH), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH), succinate, malate, isocitrate, glutamate, pyruvate, and alpha-ketoglutarate. Respiration was virtually insensitive to poisons that are commonly used to inhibit mitochondrial systems, namely, rotenone, antimycin, and azide. Succinate dehydrogenase and NADH, NADPH, and succinate oxidases were primarily membrane-bound whereas malate, isocitrate, and NADH dehydrogenases were predominantly soluble. It was observed that E. coli malate dehydrogenase could be assayed with the dye 2,6 dichlorophenol indophenol, but that porcine malate dehydrogenase activity could not be assayed, even in the presence of E. coli extracts. The characteristics of E. coli NADH dehydrogenase were shown to be markedly different from those of a mammalian enzyme. The enzyme activities for oxidation of Krebs cycle intermediates (malate, succinate, isocitrate) did not appear to be under coordinate genetic control. PMID- 4308313 TI - Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. II. Phosphatidylcholine synthesis during growth cycle and fluctuation of mitochondrial density. AB - The incorporation of methyl-labeled choline into phosphorylcholine and phosphatidylcholine of cellular membranes by Novikoff rat hepatoma cells (line N1S1-67) during growth in suspension culture was investigated. Upon initiation of a fresh culture at 10(5) cells/ml, the rate of synthesis of phosphorylcholine by the cells was four to five times greater than that of the synthesis of phosphatidylcholine. While the rate of synthesis of the latter remained relatively constant, the rate of phosphorylation of choline decreased progressively during the course of the growth cycle of the culture to 10-20% of the initial rate when the culture reached stationary phase at 3 x 10(6) cells/ml. The decrease in phosphorylcholine synthesis during the growth cycle was not due to depletion of choline in the medium or a decrease in its concentration, but was correlated with a decrease in choline kinase activity of the cells as measured in cell-free extracts. Newly synthesized phosphatidylcholine was detectable in cells only as an integral part of cellular membranes. Its distribution among various cytoplasmic membrane structures separated by isopycnic centrifugation in sucrose density gradients remained relatively constant during the growth cycle. About 50% was associated with the mitochondria, and the remainder with plasma membrane fragments and other membranous structures with mean densities of about 1.15 and 1.13 g/cm(3), respectively. However, the density of the mitochondria increased from about 1.167 g/cm(3) in early exponential phase cells to about 1.190 g/cm(3) in stationary phase cells. The finding that the density of the entire propulation of mitochondria changed simultaneously and progressively is in agreement with the view that mitochondria grow by addition of phospholipids and structural proteins and increase in number by division. PMID- 4308314 TI - Japanese encephalitis in South India. A summary of recent knowledge. PMID- 4308315 TI - Blood groups and lung cancer. PMID- 4308316 TI - Low resolution study of crystalline L-lactate dehydrogenase. PMID- 4308317 TI - Salivary gland inclusion disease in the tar- sier. PMID- 4308318 TI - Spontaneous lesions in a colony of Chinese hamsters. PMID- 4308319 TI - Isolation and characterisation of the glycopeptides of the structural glycoprotein of corneal stroma. PMID- 4308320 TI - [Comparative study of the process of activation and potentiation in mixtures of sterile and o-sterile toxins, type A, of Cl. perfringens and Cl. oedematiens]. PMID- 4308321 TI - [On the O-streptolysin efct onthe occurrence of experimental gas infection]. PMID- 4308322 TI - [Application of the immunofluorescence method to the diagnosis of parainfluenzal and adenoviral diseases]. PMID- 4308323 TI - [Roentogenological diagnosis of abdominal tumors]. PMID- 4308324 TI - Facial palsy: a medical emergency. PMID- 4308325 TI - Adenosine-3',5'-phosphate: identification as acrasin in a species of cellular slime mold. AB - Acrasin, the chemotactic agent responsible for aggregation in thecellular slime molds, has been identified for one species, Dictyostelium discoideum, as adenosine-3', 5'-phosphate. PMID- 4308326 TI - Synthesis of a model relating to the chromophores of capreomycin and viomycin. PMID- 4308327 TI - [A new instrument for testing surface sensitivity and surface reflexes]. PMID- 4308328 TI - [Cooperation between hospital practice and general practice from the viewpoint of the clinician]. PMID- 4308329 TI - The preferential loss of the polylysine- or polyornithine-stimulated activity of Clostridium perfringens polynucleotide phosphorylase during proteolysis. AB - 1. An improved method for the purification of Clostridium perfringens polynucleotide phosphorylase (nucleoside diphosphate-polyribonucleotide nucleotidyltransferase, EC 2.7.7.8) is described. The product was stable and was highly stimulated by polylysine or polyornithine. 2. It migrated as a single enzyme during sucrose-density-gradient centrifugation, and no separation of polymerization and phosphorolytic activities was observed. 3. Trypsin digestion caused a rapid, preferential loss of the polylysine- or polyornithine-stimulated activity, which was prevented by low concentrations of polyornithine. 4. The protection by polyornithine was not specific. 5. It is concluded that charge effects on the clostridial polynucleotide phosphorylase itself are primarily responsible for the stimulation of this enzyme by polylysine or polyornithine. PMID- 4308330 TI - The influence of the size and nature of basic activators on Clostridium perfringens polynucleotide phosphorylase-catalysed polyadenylic acid synthesis. AB - 1. Basic oligo- and poly-(amino acids) stimulate polyadenylic acid synthesis by purified Clostridium perfringens polynucleotide phosphorylase (nucleoside diphosphate-polyribonucleotide nucleotidyltransferase, EC 2.7.7.8). 2. The effectiveness of the activators increases with chain length up to approx. 20-30 residues. 3. Polymers of the l and dl series are equally effective on a weight for-weight basis. 4. l-Lysine, d-lysine, diethylamine and triethylamine, as hydrochlorides or hydrobromides, all stimulate the reaction markedly if their concentration is high enough. Their effect is similar to that of sodium chloride. 5. The size of the product depends primarily on the Mg(2+) concentration and basic polymers have a relatively limited effect on it. 6. Polyadenylic acid itself undergoes an Mg(2+)-catalysed non-enzymic hydrolysis. PMID- 4308333 TI - [Winkelman-McLeod dermal duct tumor (a case)]. PMID- 4308332 TI - Biosynthesis of abscisic acid: incorporation of radioactivity from [2 14C]mevalonic acid by intact fruit. PMID- 4308334 TI - Comparative epidemiological features of Japanese encephalitis in the Republic of Korea, China (Taiwan) and Japan. AB - The epidemiology of Japanese encephalitis in the Republic of Korea from 1949 to 1966 is described and comparisons are made with the situations in Japan and China (Taiwan). Some similarities and some differences are noted. Recent epidemics in Korea coincided with those in southern Japan but the annual fluctuations were more distinct in Korea. The disease mainly affected children in Korea and, in contrast to the situation in Japan, persons in the older age-groups were rarely affected. The authors also discuss the geographical pathology of Japanese encephalitis in Korea. PMID- 4308331 TI - The conversion of steroid 7,9-dienes into cholesterol. PMID- 4308335 TI - Trsmission of smallpox by contact and by aerosol routes in Macaca irus. AB - Smallpox is believed not to occur naturally in species other than man. However, reports of several epizootics of an exanthematous disease, similar to smallpox, in wild monkeys have raised the question of a simian reservoir. If such a reservoir for smallpox exists, the eradication of this disease from the world would be a difficult or impossible task. Transmission of smallpox in Macaca irus has been studied to determine whether transmission occurs and if infection chains can be maintained by this species.Transmission was consistently accomplished by both contact and aerosol routes. In the contact transmission studies, the smallpox infection was maintained through 6 passages but was lost with the seventh passage. The virulence of the virus did not appear to increase as the virus was serially passed in monkeys. Continuing studies of the possible occurrence of smallpox and of monkeypox in simian populations are warranted. PMID- 4308336 TI - Active transport of Cl- across the isolated intestinal mucosa of Testudo hermanni. PMID- 4308337 TI - [Intranuclear viroid particles in breast cancer]. PMID- 4308338 TI - Superinfection of tumors with viruses. PMID- 4308339 TI - Electron histochemical evidence of different types of mossy fibre endings in the cerebellar cortex. PMID- 4308340 TI - The involvement of cyclic 3',5'-adenosine monophosphate in the growth hormone release mechanism (s). PMID- 4308341 TI - Transcarbamylase activity and Na2H32PO4 transport in mammalian cells in culture. PMID- 4308342 TI - [Case of gastric cancer in pregnancy]. PMID- 4308344 TI - Chondromatosis: report of case. PMID- 4308343 TI - Amoebiasis in India. PMID- 4308345 TI - [Which diagnosis would you make?]. PMID- 4308347 TI - [Thoughts on various criteria of pathogenicity of staphylococci based on an "in vitro" study of 25 strains isolated from pathological specimens]. PMID- 4308348 TI - [Intravenous infusion of angiotensin for the diagnosis of arterial hypertension (Kaplan-Silah test)]. PMID- 4308346 TI - [Carbohydrate metabolism and carcinoma]. PMID- 4308349 TI - [Hypophyseal reserve in patients with peptic ulcer]. PMID- 4308350 TI - [Primary hepatic cancer and liver cirrhosis]. PMID- 4308351 TI - [Therapy of malignant tumors in childhood]. PMID- 4308352 TI - [Contribution to the angiographic diagnosis and surgical treatment of paragangliomas of the carotid body]. PMID- 4308353 TI - [Primary articular chondrocalcinosis and its clinical aspects]. PMID- 4308354 TI - [Transorbital B-echoencephalography]. PMID- 4308355 TI - Renin-angiotensin-aldosterone system in hypertension. The clinical usefulness of measuring components of thisystem. PMID- 4308356 TI - [Diagnosis and incidence of rare lung diseases. Report on a period of ten years (1958-1967)]. PMID- 4308357 TI - [Significance of renin in physiopathology and diagnosis]. PMID- 4308358 TI - [Treatment possibilities of insulin resistance]. PMID- 4308359 TI - [Experience with the homologous growth hormone in hyposomatotropism]. PMID- 4308360 TI - [Virus neutralizing antibodies against an animal experimental tumor virus (adenovirus 18) in patients with neoplastic diseases in comparison with the normal population]. PMID- 4308362 TI - [Primary neoplasms of the pelvic bones. Radiographic patterns and radiographic differential diagnosis]. PMID- 4308361 TI - [Searches for viruses during autopsies. Can a virus be held responsible for certain cases of sudden death in childhood]. PMID- 4308363 TI - [Investigation of ribonucleic acids induced by Sendai virus in the cells of Ehrlich ascites carcinoma]. PMID- 4308364 TI - [Tumour lipids. Distribution of phospholipids in mitochondria and microsomes of the Zajdela ascites rat hepatoma]. PMID- 4308365 TI - [Enzymes of hexosomonophosphate shunt in the early development of loach]. PMID- 4308367 TI - [Ectron spin resonance of substituted hn-Jerchel radicals]. PMID- 4308366 TI - [Lipids from the regenerating rat liver]. PMID- 4308368 TI - [Lipid transport hepatography in experimental occlusion of the biliary ducts]. PMID- 4308369 TI - [Hydrocortisone influence in synaptic transmission changes in the sympathetic ganglion]. PMID- 4308370 TI - [On the reliability of certain tests performed to detect carriers of hepatitis virus in transfusion practice]. PMID- 4308371 TI - [On a case of congenital adrenal hyperplasia with hypertension]. PMID- 4308372 TI - The effect of nitrogen starvation on Tenebrio molitor L. PMID- 4308373 TI - [Follow-up study of radial nerve injury. A review of 213 cases]. PMID- 4308374 TI - [Circulation and metabolism of cerebral tumors. Preoperative study]. PMID- 4308375 TI - [The application method of treating inflammatory corneal diseases with promethium 147]. PMID- 4308376 TI - [Epidemiologic peculiarities and preventive measures in an outbreak of epidemic keratoconjunctivitis in a hospital]. PMID- 4308378 TI - [Clinical value of the determination of serum 5'nucleotidase. Comparative study with serum alkaline phosphatases]. PMID- 4308377 TI - [Inhibition of natriuretic effect of angiotensin by spirolactones and salidiuretics in cirrhosis and arterial hypertension]. PMID- 4308379 TI - [Problems raised by fluorometric determination of plasma cortisol in congenital hyperplasia of adrenal glands]. PMID- 4308380 TI - [Interferon production in gelified medium: its utilization for a neutralization test by anti-interferon serum]. PMID- 4308381 TI - [Parapertussis]. PMID- 4308382 TI - [A case of malignant neoplasm in a 3-year-old child with hemigigantism of the body]. PMID- 4308383 TI - [A case of association of primary tuberculosis and cytomegaly]. PMID- 4308384 TI - [Nucleolytic enzymes in analytics]. PMID- 4308385 TI - [Localization of specific nucleases and their role in nucleic acid metabolism]. PMID- 4308386 TI - [Electron spin resonance and its application in biochemistry]. PMID- 4308388 TI - Factors in the maturation of the adrenal. PMID- 4308387 TI - [REACTION OF THE HYPOPHYSIS (ACTH) f rtftse o the changes of blood estrogen level]. PMID- 4308389 TI - Facilitatory and inhibitory influences on the pituitary-adrenal system: a study with chlorpromazine. PMID- 4308390 TI - The cental nervous system and pituitary-adrenocortical feedback mechanisms. PMID- 4308391 TI - [Our experience in pelvic lymphography with chlorophyll lipiodol]. PMID- 4308392 TI - [Studies on the silica content in guinea pig organs exposed to dusts and fumes during experimental welding with EP47-28P electrodes]. PMID- 4308393 TI - [Studies on the silica content in the liver and kidney of guinea pigs exposed to the action of dusts and fumes during welding with EP52-28P electrodes]. PMID- 4308394 TI - [Clinical picture of angina and pharyngitis of adenoviral etiology]. PMID- 4308395 TI - [On the current early therapy methods of exsudative pulmonary tuberculosis in adults]. PMID- 4308397 TI - Myoclonic encephalopathy of infants. A report of two cases and observations on related disorders. PMID- 4308396 TI - Gastric mucus and the gastric mucous barrier. A review. PMID- 4308398 TI - Atrial septal defect: results of repair in adults. PMID- 4308399 TI - Sensitivity of chick embryos to chlorpromazine. PMID- 4308400 TI - Studies on the solubilization of 2',3'-cyclic nucleotide 3'-phosphohydrolase from bovine brain. PMID- 4308401 TI - Studies on in vitro RNA synthesis in human brain tumor nuclei. PMID- 4308402 TI - Projections of the slow-conducting myelinated fibers of the splanchnic nerve on the motor cortex of the cat. PMID- 4308403 TI - Sustained evoked potential changes of the spinal cord. PMID- 4308404 TI - Steroid-sensitive neurones in rat brain: anatomical localization and responses to neurohumours and ACTH. PMID- 4308405 TI - Some factors modulating neural activities in peripheral auditory centers. PMID- 4308406 TI - Malignant non-chromaffin paraganglioma of thigh involving bone locally. PMID- 4308407 TI - Studies on the ability of compounds to block the diabetogenic activity of streptozotocin. PMID- 4308408 TI - Glomus jugulare tumors. PMID- 4308409 TI - Release of acetylcholine at voluntary motor nerve endings by H. H. Dale, W. Feldberg, M. Vogt. PMID- 4308410 TI - Relation between electrical changes during nerve activity and concentration of choline esterase by D. Nachmansohn and B. Meyerhof. PMID- 4308411 TI - Effects of lowered muscle temperature upon neuromuscular blockade in man by Eleanor Zaimis, Thomas H. Cannard, and Henry L. Price. PMID- 4308412 TI - Mode of action of streptolydigin. AB - Streptolydigin and rifamycin inhibit the catalytic function of ribonucleic acid (RNA) polymerase. Streptolydigin can inhibit polymerization after the reaction has started, whereas rifamycin is effective only if it is preincubated with RNA polymerase prior to the addition of substrates. The same relationships are observed with respect to these two antibiotics if the nucleoside triphosphate pyrophosphate exchange reaction is used in the assay system. The inhibitory effect of streptolydigin is reversible by further addition of RNA polymerase but not by addition of deoxyribonucleic acid to the assay system. PMID- 4308413 TI - Histamine-sensitizing factor, mouse-protective antigens, and other antigens of some members of the genus Bordetella. AB - The three species of the genus Bordetella-B. pertussis, B. parapertussis, and B. bronchiseptica-have many antigens in common. Studies on representative strains of these species have shown that there are only a few specific antigens in each species. Whole-cell vaccines and extracts from B. pertussis contained specific mouse-protective antigen and a histamine-sensitizing factor. In addition, whole cell vaccines and some saline extracts protected mice against intracranial challenge with B. bronchiseptica. Cells and a saline extract of B. parapertussis also protected against B. bronchiseptica but not against B. pertussis. Whole cells of B. bronchiseptica protected against B. bronchiseptica, but only one of three saline extracts protected against this challenge. Neither whole cells nor saline extracts from B. bronchiseptica protected against B. pertussis. The antigen in B. pertussis responsible for cross-protection against B. bronchiseptica was less resistant to heat than the protective antigen in B. bronchiseptica. Since histamine-sensitizing factor was not detected in B. bronchiseptica or B. parapertussis cells or extracts, this factor is not required to protect mice against B. bronchiseptica challenge. Whether B. pertussis vaccines protected against B. bronchiseptica by a nonspecific mechanism was not established, but it is clear that the specific antigen responsible for protection against B. pertussis was found only in B. pertussis and not in B. bronchiseptica or B. parapertussis. PMID- 4308414 TI - Once-a-day neurally stimulated and basal ACTH secretion phases in man and their response to corticoid inhibition. PMID- 4308415 TI - Effect of adrenocorticotropin on desoxycorticosterone, corticosterone and aldosterone excretion. PMID- 4308416 TI - Guinea pig adrenal 3-beta-hydroxysteroid dehydrogenase: is there more than one enzyme? PMID- 4308419 TI - Entero-and myxoviral infections of the central nervous system. PMID- 4308417 TI - Neurotransmission in central nervous tissue: a study of isolated rabbit retina. PMID- 4308418 TI - [Current status of nephrology]. PMID- 4308420 TI - Structural difference in sites on the surface membrane of normal and transformed cells. PMID- 4308421 TI - Immune complexes in mice infected neonatally with Moloney leukaemogenic and murine sarcoma viruses. PMID- 4308422 TI - Iprindole: an antidepressant which does not block REM sleep. PMID- 4308423 TI - Dietary iodine and goiter in Ceylon. PMID- 4308424 TI - [Hunter's dermatoses]. PMID- 4308426 TI - Virus abortion in california. PMID- 4308425 TI - Screening of food handlers. PMID- 4308428 TI - Differential diagnosis of avian viral respiratory diseases: a comparison of fluorescent antibody and virus isolation techniques. PMID- 4308427 TI - Foot-and-mouth disease in man--notes on a recent case. PMID- 4308430 TI - [Benign insuloma--3 case reports]. PMID- 4308429 TI - [Hanot-Kiener disease, diffuse mesenchymatous hepatitis with nodular lymphomatosis. Histological and cytological study; tri-dimensional reconstruction]. PMID- 4308431 TI - [On the diagnosis of intestinal amebiasis]. PMID- 4308432 TI - [Cytophotometric studies of the DNA and histone content of experimentally-induced tumors of the central nervous system of the rat]. PMID- 4308433 TI - [On the modification of the Theurer's treatment with autogenous blood. Countersensitization]. PMID- 4308434 TI - [Action of various hypertensive drugs on pulmonary and systemic hemodynamics]. PMID- 4308436 TI - [Physiology and physiopathology of the neuromuscular junction]. PMID- 4308435 TI - [Hepatic inactivation of synthetic angiotensin II injected into the human portal vein through the umbilicus]. PMID- 4308437 TI - [Sleep and dream deprivation]. PMID- 4308438 TI - [Studies on the effect of vagotomy on certain histochemical reactions of the stomach glands]. PMID- 4308439 TI - [Studies of the influence of vagotomy on histochemical responses in the epithelial cells and duodenal glands]. PMID- 4308440 TI - [Resistance of tubercle bacilli to cycloserine, viomycin and ethionamide in patients suffering from pulmonary tuberculosis]. PMID- 4308441 TI - [Enzymological studies on theca cell neoplasms]. PMID- 4308442 TI - Determination of the ability of streptomycetes to utilize carbon sources by the method of culturing on silica gel. PMID- 4308443 TI - [Serum antibodies hemagglutino-inhibiting the hemadsorption viruses of types 1 and 3 and croup associated in individuals from Accra (Ghana)]. PMID- 4308444 TI - [Which influence does antibiotic therapy have on neonatal mortality?]. PMID- 4308446 TI - [Persistance of a stimulated character in primitive virus cultivated in the presence of anti-interferon serum]. PMID- 4308445 TI - [Small intestinal agenesis with multiple abnormalities]. PMID- 4308448 TI - [Regulation of the alcohol dehydrogenases Saccharomyces cerevisiae]. PMID- 4308450 TI - [Therapy of multiple sclerosis]. PMID- 4308447 TI - [Evaluation of the conductive velocity of individual motor nerve fibre bundles. A neurophysiological study]. PMID- 4308449 TI - Liver 3':5'-nucleotide phosphodiesterase and its activity in rat livers perfused with insulin. PMID- 4308451 TI - [Isolation of poliomyelitis virus and various enteroviruses from the sewage of the city of Dushambe]. PMID- 4308452 TI - [A comparative-experimental study of the absorption of proteins onto the surface of quartz dust modified by various silanes]. PMID- 4308453 TI - [Contribution on mammography]. PMID- 4308454 TI - [Current treatment of trophoblastic tumors]. PMID- 4308455 TI - Enzyme histochemistry of the pars intermedia of ox pituitary gland. PMID- 4308456 TI - Cilia in cell-cultured fibroblasts. I. On their occurrence and relative frequencies in primary cultures and established cell lines. PMID- 4308457 TI - A method for extraction and chromatographic isolation, purification and identification of tetrahydrocannabinol and other compounds from marihuana. PMID- 4308458 TI - [On a case of corneal abscess due to Bacillus pyocyaneus]. PMID- 4308459 TI - [Peptic ulcer in childhood]. PMID- 4308460 TI - [Myoclonic encephalopathy with hypsarrhythmia in children]. PMID- 4308461 TI - [Intravenous hormono-chemotherapy of patients with chronic forms of pulmonary tuberculosis]. PMID- 4308462 TI - [Asymptomatic infection with foot-and-mouth disease in humans]. PMID- 4308463 TI - [Changes in blood pressure level in boys during puberty. I. Pressure and indices of somatic maturity]. PMID- 4308464 TI - [Gastro-enterological practice in general medicine]. PMID- 4308465 TI - [Acute renal failure revealing Kahler's disease. Recovery with a 13-month follow up. Value of peritoneal dialysis]. PMID- 4308466 TI - [Orchitis, the only manifestation of a paratyphoid B fever]. PMID- 4308467 TI - [A case of reversible exsudative enteropathy during lymphoma]. PMID- 4308468 TI - [Dangerous diagnostical cross-roads: the sub-hepatic cross-roads]. PMID- 4308469 TI - [Comparative study of oral treatment in diabetes]. PMID- 4308470 TI - [Diagnosis, therapy and prognosis of malignant testicular neoplasma]. PMID- 4308471 TI - [Detection, purification and characteristics of a peptidyl-peptide-hydrolase (collagenase) from liver and spleen of the rabbit]. PMID- 4308472 TI - [Animal experiment study on the pathogenesis of placenta praevia]. PMID- 4308473 TI - [Detection of thermo-resistant strains of Cl. perfringens type A in the feces of humans]. PMID- 4308474 TI - Sleep. PMID- 4308476 TI - Properties of the corticotrophin-releasing factor of the rat median eminence. PMID- 4308475 TI - Effects of chemical and enzymatic modifications of glucagon on its activation of hepatic adenyl cyclase. PMID- 4308477 TI - Response of rat adrenal tissue to ACTH in a flowing system. PMID- 4308478 TI - Role of cyclic AMP in mediating the effects of MSH, norepinephrine, and melatonin on frog skin color. PMID- 4308479 TI - Interrelationships between thyrocalcitonin, parathyroid hormone and vitamin D: control of serum calcium in hypervitaminosis D. PMID- 4308481 TI - Hypothalamic control of ACTH release from ectopic pituitary glands. PMID- 4308480 TI - 2-Thiophenecarboxylic acid: a hypoglycemic, antilipolytic agent with hypocalcemic and hypophosphatemic effects in rats. PMID- 4308482 TI - Long-term feeding studies of methyl ethyl cellulose ('Edifas' A) and sodium carboxymethyl cellulose ('Edifas' B) in rats and mice. PMID- 4308483 TI - Synergism in carcinogenesis. PMID- 4308484 TI - Carcinogenicity of sterigmatocystin. PMID- 4308485 TI - Free radicals in irradiated single crystals of 5-halo-uracil derivatives: 5 bromouracil, 5-bromodeoxyuridine and 5-iododeoxyuridine. PMID- 4308486 TI - Schwann-cell proliferation in chronic neuropathies. PMID- 4308487 TI - Role of interferon in replication of virulent and attenuated strains of measles virus. PMID- 4308488 TI - Rescue of Rous sarcoma virus from virogenic mammalian cells associated with chicken cells and treated with Sendai virus. PMID- 4308489 TI - Electrophoretic properties of foot-and-mouth disease virus strains and the selection of intra-strain mutants. PMID- 4308490 TI - A host-cell DNA function involved in the replication of avian tumour viruses and of fowl-plague virus. PMID- 4308491 TI - Activation of a mammary tumour virus in O20 strain mice by x-irradiation and urethane. PMID- 4308492 TI - Antiviral and cytotoxic effects of mycophenolic acid. PMID- 4308493 TI - The structure of foot-and-mouth disease virus protein. PMID- 4308494 TI - [Histochemical and biochemical studies on the effects of anticancer agents on glycogen metabolism in AH13 ascites hepatoma]. PMID- 4308495 TI - Studies on mitochondrial tRNA from animal cells. I. A comparison of mitochondrial and cytoplasmic trna and aminoacyl-tRNA synthetases. PMID- 4308497 TI - [Electron structure of the prosthetic group and tertiary structure in hemoproteins. 3. pH-dependent hemoglobin(3)-dodecyl sulfate complexes]. PMID- 4308496 TI - Methylation of mammalian DNA: studies on Novikoff hepatoma cells in tissue culture. PMID- 4308498 TI - Heterogeneity of polyoma virus DNA: isolation and characterization of non infectious small supercoiled molecules. PMID- 4308500 TI - [New chemotherapy of malignant tumors in pediatrics]. PMID- 4308499 TI - Some aspects of the pharmacology of valyl-beta-(pyrazolyl-3)-L-alanyl6 angiotensin II. PMID- 4308502 TI - [3 Cases of skin tumors]. PMID- 4308503 TI - [Case of jugal bone melanotic progonoma in a child]. PMID- 4308501 TI - [Autopsy case of mucinous cell carcinoma of the stomach with extensive calcification]. PMID- 4308504 TI - [Determination of 17-ketogenic steroids. 1. Comparison between indirect and direct methodw with NaBi03 and NaIO4 methods]. PMID- 4308505 TI - [Effect of hypoxia of the myocardium on the reactivity of the coronary vessels]. PMID- 4308506 TI - The effect of alpha-methyl-para-tyrosine on sleep patterns of the monkey. PMID- 4308507 TI - Potentiation of the anticalorigenic action of the adrenergic beta-receptor antagonist MJ 1999 by cyclic 3',5'-AMP. PMID- 4308509 TI - Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation. PMID- 4308508 TI - Cofactor requirements for metabolism of alpha-amino-n-butyric acid by brain homogenates. PMID- 4308510 TI - Phospholipid metabolism and adrenal medullary activity. I. The effect of acetylcholine on tissue uptake and incorporation of orthophosphate-32P into nucleotides and phospholipids of bovine adrenal medulla. PMID- 4308511 TI - The effect of Ca++ omission on the secretion of catecholamines and the incorporation of orthophosphate-32P into nucleotides and phospholipids of bovine adrenal medulla during acetylcholine stimulation. PMID- 4308513 TI - Induction of rat kidney tumours by ethyl methanesulphonate and nervous tissue tumours by methyl methanesulphonate and ethyl methanesulphonate. PMID- 4308512 TI - Human brain protein, drugs and dreams. PMID- 4308515 TI - Longstanding haemochromatosis with polyarthritis and terminal hepatoma. PMID- 4308514 TI - Remitting demyelinating disease associated with myeloproliferative syndrome and histiocytosis of the spleen. PMID- 4308516 TI - Insulinoma presenting with episodic attacks of transient unconsciousness. PMID- 4308517 TI - Malignant disease in juveniles. PMID- 4308518 TI - The value of mercury perchloride and other agents in reducing tumour recurrence in colon anastomosis. PMID- 4308519 TI - Irrigation via self-retaining rectal tube in prevention of suture-line recurrent carcinoma. PMID- 4308520 TI - [Alpha to delta nocturnal routine trip]. PMID- 4308521 TI - Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo. AB - Two diphosphonates containing the P-C-P bond, CH(3)C(OH)(PO(3)HNa)(2) and H(2)C(PO(3)HNa)(2), inhibit the crystallization of calcium phosphate in vitro and prevent aortic calcification of rats given large amounts of vitamin D(3). The diphosphonates therefore have effects similar to those described for compounds containing the P-O-P bond but are active when administered orally. PMID- 4308522 TI - [Hypoglycemia in Langerhans' island tumor--our cases and statistical and surgical observation]. PMID- 4308523 TI - [Problems of blood coagulation disorders in neurosurgery]. PMID- 4308524 TI - Neuropathological studies on myelomatosis. PMID- 4308525 TI - Two studies of childhood dreaming. PMID- 4308526 TI - Roentgenologic studies of cerebrospinal fluid formation in the dog. PMID- 4308527 TI - Lipid embolism to the brain following lymphography. Case report and experimental study. PMID- 4308528 TI - Vascular structure of glioblastomas. PMID- 4308529 TI - Mammographic technique: need for routine spot roentgenograms. PMID- 4308530 TI - Effects of insecticides on mammalian cells and virus infections. PMID- 4308531 TI - The significance of simian viruses to the monkey colony and the laboratory investigator. PMID- 4308532 TI - Recent advances in the study of simian viruses. PMID- 4308533 TI - Subhuman primates in experimental viral oncology. PMID- 4308534 TI - Diseases of primates affecting the choice of species for toxicologic studies. PMID- 4308535 TI - In vitro antiviral activity of mycophenolic acid and its reversal by guanine-type compounds. AB - With the agar diffusion test and BS-C-1 cells, mycophenolic acid was found to give a straight-line dose-response activity in inhibiting the cytopathic effects of vaccinia, herpes simplex, and measles viruses. Plaque tests have shown 100% reduction of virus plaques by mycophenolic acid over drug ranges of 10 to 50 mug/ml and virus input as high as 6,000 plaque-forming units (PFU) per flask. Back titration studies with measles virus inhibited by mycophenolic acid have indicated that extracellular virus titers were reduced by approximately 3 logs(10) and total virus was reduced by 1 log(10). The agar diffusion test system lends itself readily to drug reversal studies. Mycophenolic acid incorporated into agar at 10 mug/ml gave 100% protection to virus-infected cells. Filter paper discs impregnated with selected chemical agents at concentrations of 1,000 mug/ml (20 mug per filter paper disc) were placed on the agar surface. Reversal of the antiviral activity of mycophenolic acid was indicated by virus breakthrough in those cells in close proximity to the filter paper disc. Chemicals showing the best reversal of the antiviral activity of mycophenolic acid were guanine, guanosine, guanylic acid, deoxyguanylic acid, and 2,6-diaminopurine. The reversal of antiviral activity was confirmed by titrations of virus produced with various amounts of both mycophenolic acid and guanine present and by isotope tracer methods with uptakes of labeled uridine, guanine, leucine, and thymidine in treated and nontreated, infected and noninfected cells as parameters. All antiviral effects of mycophenolic acid at 10 mug/ml could be reversed to the range shown by untreated controls by the addition of 10 mug/ml of those chemicals exhibiting reversal activity. PMID- 4308536 TI - Fluorescent-antibody studies with antisera against heated and unheated poliovirus type 1. AB - Fluorescent-antibody (FA) reagents were prepared from sera of guinea pigs immunized with either native infectious poliovirus type 1 or poliovirus type 1 which had been heated at 56 C for 30 min. Conjugates made from sera of animals immunized with heated virus gave higher direct FA staining titers on air-dried, acetone-fixed, infected cells than conjugates made from sera of animals immunized with native infectious virus. Evidence was obtained that complement-fixing antibody reactive with heated antigen was responsible for the FA staining. Two conjugates prepared from sera of guinea pigs immunized with heated poliovirus type 1 were successfully used to identify 21 type 1 viruses isolated from a group of 44 stool suspensions studied as unknowns. These conjugates did not stain any of 23 heterologous enteroviruses present in the remainder of the stools and gave minimal non-specific staining. PMID- 4308537 TI - Insulinoma in childhood. PMID- 4308538 TI - Variation in the size of the kidney during nephro-angiography in anaesthetised dogs. PMID- 4308539 TI - [The significance of enzyme diagnosis for the general practitioner]. PMID- 4308540 TI - [New investment without adhesive agents]. PMID- 4308541 TI - [Collagenolytic activity during root resorption of bovine deciduous tooth. I. Activity of collagenase]. PMID- 4308542 TI - The effect of antioxidant-deficiency on phospholipid composition in the chick brain. PMID- 4308544 TI - Evaluation of nerve injuries by evoked potentials and electromyography. PMID- 4308543 TI - Biosynthesis of aspartic, glutamic, gamma-aminobutyric acids and glutamine in brain of rats deprived of total sleep or paradoxical sleep. PMID- 4308545 TI - Regional cerebral blood flow in patients with intracranial tumors. PMID- 4308546 TI - Ultrasonic echo examination as an aid in diagnosis of congenital bile duct lesions. PMID- 4308547 TI - [Study on the renin-angiotensin-aldosterone system. Evaluation of the dynamics of renal renin and adrenal cortex aldosterone production in the chronic stage of Goldblatt's rats]. PMID- 4308548 TI - Physical studies of lipid-lipid and lipid-protein interactions. PMID- 4308549 TI - Triglyceride sub-classes of dog plasma and organs. PMID- 4308551 TI - [Cholelithiasis in scorbutic guinea pigs]. PMID- 4308550 TI - The relation of carnitine to the formation of phosphatidyl-beta-methylcholine by Tenebrio molitor L. larvae. PMID- 4308552 TI - Skin lesions of the breast. PMID- 4308553 TI - Food-and-mouth disease viremia. PMID- 4308554 TI - Immunogenicity of nanogram to milligram quantities of inactivated foot-and-mouth disease virus. II. Comparative response of guinea pigs and steers. PMID- 4308555 TI - Outbreak of malignant catarrhal fever in kansas. PMID- 4308556 TI - [Comparative study of the effects of Ayerogen with equanil sodium sulphate in climacteric women]. PMID- 4308557 TI - [Neurological complications of diabetes mellitus]. PMID- 4308558 TI - [Massive corticotherapy in the treatment of septicemic collapse]. PMID- 4308559 TI - [Effect on glycemic equilibrium of massive corticotherapy used in the treatment of septic collapse in metabolic resuscitation]. PMID- 4308560 TI - [Electromanometric study of the action of metoclopramide in man]. PMID- 4308561 TI - [Apropos of myasthenia gravis and its treatment]. PMID- 4308562 TI - [The position of general practitioner in relation to gerontology]. PMID- 4308563 TI - [Clinical trial of a new antihypertensive agent]. PMID- 4308564 TI - Electron microscopic study on RNA of cytoplasmic polyhedrosis virus of the silkworm. PMID- 4308565 TI - Inhibition of poliovirus replication by N-methylisatin-beta-4':4' dibutylthiosemicarbazone. PMID- 4308566 TI - The effect of magnesium on the intracellular crystallization of rhinovirus. PMID- 4308568 TI - Selective failure of protein synthesis in herpesvirus-infected cells deprived of arginine. PMID- 4308567 TI - Multiplicity of viral genomes in an SV40 transformed hamster cell line. PMID- 4308570 TI - The metabolism of small and of large amounts of progesterone in man. PMID- 4308569 TI - [On the increased spindle activity in the sleep EEG of children with phenylketonuria]. PMID- 4308571 TI - Immunological studies on the membrane systems of cancer cells. I. Immunochemical analysis of membrane fractions from cancer cells. PMID- 4308572 TI - Desynchronized sleep during human ontogenesis. PMID- 4308574 TI - Are stages of sleep really necessary? PMID- 4308573 TI - Vigilance changes in rats with different levels of nonspecific excitability. PMID- 4308575 TI - The nature of all night sleep patterns. PMID- 4308576 TI - Quantitative representation of the course of sleep based on the frequency distribution of EEG patterns. PMID- 4308577 TI - Relation of sleep onset to rapid eye movement sleep. PMID- 4308578 TI - Waking fantasies following interrupted and completed REM periods. PMID- 4308579 TI - Penile erections during sleep. PMID- 4308580 TI - Tourniquet poditis--an experimental pedal inflammation in the rat. PMID- 4308582 TI - Immunohistological studies of mice infected with bordetella pertussis. PMID- 4308581 TI - Entamoeba histolytica-like amoebae occurring in man. AB - Six Entamoeba histolytica-like amoebae of the Laredo-type are compared with classical E. histolytica strains with regard to morphology, temperature tolerance, response to hypotonic solutions, antigenic make-up, pathogenicity, sensitivity to drugs, and biochemistry. Sharp discontinuities are shown to exist between the 2 groups in some parameters, sufficient, under certain conditions, to justify creation of a new species designation for the Laredo-type amoebae. Nevertheless, this action is not recommended at the present time because of the small number of "aberrant" strains so far isolated, and because of the limited comparative studies so far carried out.Entamoeba moshkovskii is compared with the Laredo-type E. histolytica. No consistent distinction can be made between the 2 groups except for the sources of the strains-the former is free-living and the latter parasitic. It is therefore suggested that E. moshkovskii may actually be a parasite of the Laredo type, only incidentally encountered in free-living environments because of its wide temperature and tonicity tolerances. Since, here too, only limited studies are so far available, it is suggested that the term "moshkovskii-like E. histolytica" be used until sufficient data are accumulated to assign these amoebae to a more precise location in the taxonomic scheme. PMID- 4308583 TI - [Phosphatase activity of soil actinomycetes]. PMID- 4308585 TI - [Symposium on problems in the clinical pharmacology of coronary dilators. Introduction]. PMID- 4308586 TI - [Action of reactivators in phosphoric acid ester poisoning]. PMID- 4308584 TI - [Nipiopharmacology of the anterior hypophysis hormones]. PMID- 4308587 TI - [On the mechanism of the cardiac effects of 2-bromo-LSD]. PMID- 4308588 TI - [Hormonal influences on the formation of cyclic adenosine 3'-5'-monophosphate in the rat kidney]. PMID- 4308590 TI - Melanotic neuroectodermal tumour of infancy. Report of 2 cases. PMID- 4308589 TI - [Effect of heterocyclic lipolysis inhibitors on the activity of 3',5'-AMP phosphodiesterase]. PMID- 4308592 TI - [The association of polymyxin and terramycin in external dermatological therapy]. PMID- 4308591 TI - [Dangers in the use of various rheumatic drugs]. PMID- 4308593 TI - Metabolic events associated with steroid biosynthesis in adrenal tissue cultures. PMID- 4308594 TI - Failure to diagnose Addison's disease and value of tetracosactrin (Synacthen) stimulation test. PMID- 4308595 TI - [Dogs--carriers of intestinal adenoviruses antigenically close to similar viruses in man. II]. PMID- 4308596 TI - [Extraction of dry concentrated toxin from Cl. perfringens type E]. PMID- 4308597 TI - Synergistic and inhibitory activity of various hormones on the exophthalmo producing factor in sera of patients suffering from endocrine exophthalmos. PMID- 4308598 TI - The half-life of porcine corticotrophin in pigs. PMID- 4308601 TI - Rapid fluorometric analysis of plasma corticosteroids as a test of adrenocortical function in the dog. PMID- 4308600 TI - Quantitative relationship of preexisting homotypic antibodies to excretion of poliovirus types 1, 2, and 3 following the feeding of trivalent attenuated poliovirus vaccine. PMID- 4308599 TI - Inhibitory effect of diphenylhydantoin on the feedback control of corticotrophin release. PMID- 4308602 TI - Physicochemical characteristics of a bovine enterovirus prototype. PMID- 4308603 TI - Characterization of Cal-1 strain of acute Marek's disease agent. PMID- 4308604 TI - Syndactyly in an Aberdeen Angus calf. PMID- 4308605 TI - Ribonucleases. PMID- 4308606 TI - Enzymes in DNA metabolism. PMID- 4308607 TI - Polypeptide hormones. PMID- 4308608 TI - Chemical synthesis of peptides. PMID- 4308609 TI - Management of nonpalpable breast carcinoma discovered by mammography. PMID- 4308611 TI - [Treatment of hypersensitivity to sun rays by means of ACTH]. PMID- 4308610 TI - Nucleic acid metabolism in the ruminant. Determination of nucleic acids in digesta. PMID- 4308612 TI - Temporal relationships of puromycin and ACTH effects on cultured hamster adrenal glands. PMID- 4308613 TI - The presence of alkenyl and alkyl glycerides, and choline and ethanolamine plasmalogens in a marine worm. PMID- 4308614 TI - Paralysing venoms of solitary wasps. PMID- 4308615 TI - Lipids of the larvae and adults of Trogoderma granarium (Coleoptera). PMID- 4308616 TI - Effect of hydroxylamine on respiration and oxidative phosphorylation. PMID- 4308617 TI - [Species specific polysaccharide-rich cell membrane antigens of Dictyostelium discoideum]. PMID- 4308619 TI - The effect of tegretol on some elementary neuronal mechanisms. PMID- 4308618 TI - The subcellular distribution of acyltransferases which catalyze the synthesis of phosphoglycerides. PMID- 4308621 TI - Electron microscopic studies of anterior pituitary glands of vitamin E-deficient male mice. PMID- 4308620 TI - Studies on the serum proteins of chimeras. 3. Detection of donor-type C'5 in allogeneic and congenic post-irradiation chimeras. PMID- 4308622 TI - Correlation of electron microscopic and biochemical studies on constricted monoaminergic nerves. PMID- 4308623 TI - [Simple rapid measurement of urinary HCG and its clinical application. Slide test Gravindex]. PMID- 4308624 TI - The effects of theophylline, diazoxide and imidazole on isoproterenol-induced inhibition of the rabbit ileum. PMID- 4308625 TI - Inhibitory effects of alloxan on mammalian adenyl cyclase. PMID- 4308626 TI - The effect of digitalis on the excitability of autonomic nerves. PMID- 4308627 TI - An ultrastructural study of the adrenocorticotrophic hormone-secreting cell in the rat adenohypophysis during adrenal cortical regeneration. PMID- 4308629 TI - Reduced adenosine 3',5'-monophosphate phosphodiesterase activity in the pancreas and adipose tissue of spontaneously diabetic mice. PMID- 4308628 TI - A comparison of the properties of pyruvate kinase from hepatoma 3924-A, normal liver and muscle. PMID- 4308630 TI - Mg2+-induced shrinkage in mitochondria isolated from Yoshida ascites hepatoma. PMID- 4308631 TI - Formation of prototrophs in mixtures of two auxotrophic mutants of Serratia marcescens HY by a transducing bacteriophage produced by some auxotrophs. PMID- 4308632 TI - [Glycogen metabolism abnormalities]. PMID- 4308633 TI - [Paralyzing sciatica. (Clinico-therapeutic considerations on 70 operated patients)]. PMID- 4308634 TI - [Non-traumatic progressive paralysis of the deep branch of the radial nerve]. PMID- 4308635 TI - [The paradoxical phase of sleep, dreams and the psychosomatic unity]. PMID- 4308636 TI - [Physiopathologic significance of binephrectomy in arterial hypertension]. PMID- 4308637 TI - [Experimental immuno-pathologic studies on silicosis. 3. Influence of a state of immunologic hypersensitivity on silicogenic fibrosis]. PMID- 4308638 TI - Cyclic adenosine monophosphate: possible mediator for norepinephrine effects on cerebellar Purkinje cells. AB - Microelectrophoretic application of norepinephrine or cyclic adenosine monophosphate reduces the discharge frequency of Purkinje cells in the rat cerebellum. In contrast, other nucleotides accelerate the discharge rate of most units. Parenterally administered theophylline, which inhibits the hydrolysis of cyclic adenosine monophosphate enhances the effects of norepinephrine and cyclic adenosine monophosphate. Therefore, norepinephrine may be able to regulate Purkinje cells functionally by metabolic stimulation of cyclic adenosine monophosphate synthesis. PMID- 4308639 TI - C-fiber responses in the ventrolateral column of the cat spinal cord. AB - Saphenous nerve C-fiber volleys generate, in the ventrolateral column of the cat spinal cord, a conducted postsynaptic response revealed by averaging the integrated temporally dispersed axonal discharges. This finding is compatible with the hypothesis that the feline ventrolateral column includes a major pathway related to nociception. PMID- 4308640 TI - [For child psychiatry]. PMID- 4308641 TI - [SA hemoglobinosis and osteomyelitis]. PMID- 4308642 TI - [Contribution to the study of the repartition of hemoglobins in Africans and Madagascans]. PMID- 4308643 TI - [New studies on a relationship between hemoglobins and rhesus factors in Africans]. PMID- 4308645 TI - [A case of stiff man syndrome]. PMID- 4308644 TI - [Thalassemia minor in a Swedish family]. PMID- 4308646 TI - [Treatment of depressive states by amitriptyline. Trial of the "drinkable solution" form]. PMID- 4308648 TI - [Generalized follicular mucinosis revealing cutaneous and bronchopulmonary histiomonocytic reticulosis oa case]. PMID- 4308647 TI - [Is the portal system thrombosis of the cirrhotic patient latent?]. PMID- 4308650 TI - [Hemorrhagic necrosis of the digestive tract and heart failure]. PMID- 4308649 TI - [Significance and biological consequences of several histological and ultrastructural anomalies observed in subacute alcoholic hepatitis]. PMID- 4308651 TI - [Launosis-Bensaude symmetric adenolipomatosis and disorders of lipid metabolism]. PMID- 4308652 TI - [Value of retrograde humeral arteriography in cervico-thoracic pathology]. PMID- 4308653 TI - [Radiologic examination of Egyptian mummies in Danish museums]. PMID- 4308654 TI - [Contribution to the study of the narrow lumbar canals. Radiological technique and normal value]. PMID- 4308655 TI - [Study of the lumbar osseous canal in common vertebral sciatica]. PMID- 4308656 TI - [Sciatica and cauda equina syndrome due to pseudo-spondylolisthesis]. PMID- 4308658 TI - [Thyroid nodule: diagnostic and therapeutic problems]. PMID- 4308659 TI - [Fatty embolism of the retina]. PMID- 4308657 TI - [Hypercalcemia and electroencephalographic anomalies. Apropos of an observation of Kahler's disease with hypercalcemia]. PMID- 4308660 TI - [Generalized cutaneous trichophytids]. PMID- 4308661 TI - [Report on long-term corticotherapy by delayed-action methylprednisolone in 100 gastric ulcer patients]. PMID- 4308662 TI - [Certification of decease]. PMID- 4308663 TI - [Severe toxic hepatitis]. PMID- 4308664 TI - [Acute poisoning by short-acting barbiturates. Current clinical and medico-legal aspects]. PMID- 4308666 TI - [Regional medico-legal centre. Experience in Lyon]. PMID- 4308665 TI - [Fatal therapeutic complications]. PMID- 4308667 TI - [Influence of the geomagnetism of cosmic origin on the human organism]. PMID- 4308668 TI - [Clinical study in neurology of 50 mg pentazocine pills by a double-blind method]. PMID- 4308669 TI - [Primary bronchial cancer before the age of 40]. PMID- 4308670 TI - [Tuberculosis in a general medicine department in black Africa]. PMID- 4308671 TI - [Present developmental aspect of infectious endocarditis. According to hospital statistics of 103 consecutive cases collected in the last 12 years]. PMID- 4308672 TI - ["Allergic" granulomatous angeitis]. PMID- 4308673 TI - [Deficiencies of the abdominal wall in aged persons]. PMID- 4308674 TI - The minimal infectious dose of adenovirus type 4; the case for natural transmission by viral aerosol. PMID- 4308675 TI - Diseases of the facial nerve. PMID- 4308676 TI - [Urinary excretion of 6-beta-hydroxycortisol and other polar corticosteroids in puberty and its changes by ACTH loading]. PMID- 4308677 TI - A clinical syndrome and EEG-sleep changes associated with amino acid deprivation. PMID- 4308678 TI - [Jaffe-Lichtenstein's fibrous dysplasia. (Apropos of a case with biological anomalies)]. PMID- 4308679 TI - The stability of angiotensinamide in aqueous solution. PMID- 4308680 TI - [Blood serum level of copper in neoplasms of the respiratory tract]. PMID- 4308681 TI - Biochemical studies on marine shellfish lipid. II. Glycolipid of oyster mantle. PMID- 4308682 TI - Studies on cytochrome b-555 from larvae of the housefly, Musca domestica L. I. Purification and properties of cytochrome b-555. PMID- 4308683 TI - Nucleotide sequence of tyrosine transfer RNA from Torulopsis utilis. PMID- 4308684 TI - Phosphatases and differentiation of the Golgi apparatus. PMID- 4308685 TI - Recovery of cholinesterase activity in organophosphate treated insects. PMID- 4308686 TI - Electron microscopic studies of polyoma DNA released in protein monolayers. PMID- 4308687 TI - Allosteric changes in citrate synthase observed by electron microscopy. PMID- 4308688 TI - Interaction between cytomegalovirus and Newcastle disease virus as mediated by intrinsic interference. AB - Cytomegalovirus (CMV) was demonstrated to induce intrinsic interference to Newcastle disease virus (NDV) in human fibroblast cells under noncytopathic conditions. This interference is unique in that (i) cytomegalovirus is the first DNA virus demonstrated to have this property and (ii) the state of interference was transient and progressively lost as the condition of the cells changed with the development of cytopathic effect. These observations are consistent with the view that the newly formed protein responsible for interference with NDV has a limited half-life and is no longer made when cytopathic conditions are produced by CMV. PMID- 4308689 TI - Ribonucleic acid synthesis in cells infected with herpes simplex virus. I. Patterns of ribonucleic acid synthesis in productively infected cells. AB - HEp-2 cells were pulse-labeled at different times after infection with herpes simplex virus, and nuclear ribonucleic acid (RNA) and cytoplasmic RNA were examined. The data showed the following: (i) Analysis by acrylamide gel electrophoresis of cytoplasmic RNA of cells infected at high multiplicities [80 to 200 plaque-forming units (PFU)/cell] revealed that ribosomal RNA (rRNA) synthesis falls to less than 10% of control (uninfected cell) values by 5 hr after infection. The synthesis of 4S RNA also declined but not as rapidly, and at its lowest level it was still 20% of control values. At lower multiplicities (20 PFU), the rate of inhibition was slower than at high multiplicities. However, at all multiplicities the rates of inhibition of 18S and 28S rRNA remained identical and higher than that of 4S RNA. (ii) Analysis of nuclear RNA of cells infected at high multiplicities by sucrose density gradient centrifugation showed that the synthesis and methylation of 45S rRNA precursor continued at a reduced but significant rate (ca. 30% of control values) at times after infection when no radioactive uridine was incorporated or could be chased into 28S and 18S rRNA. This indicates that the inhibition of rRNA synthesis after herpesvirus infection is a result of two processes: a decrease in the rate of synthesis of 45S RNA and a decrease in the rate of processing of that 45S RNA that is synthesized. (iii) Hybridization of nuclear and cytoplasmic RNA of infected cells with herpesvirus DNA revealed that a significant proportion of the total viral RNA in the nucleus has a sedimentation coefficient of 50S or greater. The sedimentation coefficient of virus-specific RNA associated with cytoplasmic polyribosomes is smaller with a maximum at 16S to 20S, but there is some rapidly sedimenting RNA (> 28S) here too. (iv) Finally, there was leakage of low-molecular weight (4S) RNA from infected cells, the leakage being approximately three-fold that of uninfected cells by approximately 5 hr after infection. PMID- 4308690 TI - Influence of the rate of cell growth and cell density on interferon action in chick embryo cells. AB - Chick embryo cells became more sensitive to the action of interferon the longer they remained in culture. This phenomenon was found even before confluency had been reached. The relative insensitivity of newly seeded cells was not due to a loss of receptors. Cells synthesizing deoxyribonucleic acid (DNA) at a high rate were less sensitive to interferon action than cells synthesizing DNA at a low rate, but the inhibition of DNA synthesis had no effect on interferon action. An increase in the number of cells used for seeding resulted in an earlier appearance of increased sensitivity to interferon action. These results are discussed in relation to the induction process in animal cells. PMID- 4308691 TI - [Phosphorus acid isolation from apatite produced by silicate bacteria]. PMID- 4308692 TI - [Observations of potentiation of toxins of Clostridium perfringens and Clostridium histolyticum]. PMID- 4308693 TI - [On joint action of toxins of Clostridium perfringens, Cl. oedematiens and Cl. septicum and biological products of Cl. butyricum on hemolytic and lethal properties of these toxins]. PMID- 4308694 TI - [Study of the activity of various combinations of toxins of Clostridium perfringens, Cl. oedematiens and Cl. septicum in in vitro and in vivo experiments]. PMID- 4308695 TI - [Adaptation of Sonne and Flexner dysentery bacteria to antibiotics and some biological properties of adapted subcultures]. PMID- 4308696 TI - [Some data on the character and nature of adenovirus inclusion]. PMID- 4308697 TI - [Some enzymes of carbohydrate metabolism in fungi of the genus Fusarium]. PMID- 4308698 TI - [Immunofluorescent investigations of serological homogeneity of Cl. perfringens and its radiation mutants]. PMID- 4308700 TI - [Electron microscopy in the study of cutaneous epithelial precancerous conditions]. PMID- 4308699 TI - [Phosphatase activity of intact cells of Bacillus subtilis and Bacillus mesentericus]. PMID- 4308701 TI - [Effect of prolonged treatment with adrenocortical hormones on the growth of children with lipid nephrosis]. PMID- 4308702 TI - [Diagnostic usefulness of intravenous infusions of angiotensin solution (Kaplan's test) in patients with arterial hypertension]. PMID- 4308703 TI - An alkaline phenylbutazone preparation. PMID- 4308704 TI - [On plaque formation by the herpes simplex virus]. PMID- 4308705 TI - [A familial outbreak of adenovirus type 21 infection (follicular conjunctivitis)]. PMID- 4308706 TI - [On the possible conversion of 5'-hydroxymethlcytosine into cytosine in tumor cells]. PMID- 4308707 TI - [Obtaining highly purified preparations of Cl. histolyticum lethal factor]. PMID- 4308708 TI - [Study on the glycolytic ability of cell-free ascites Ehrlich tumor extract]. PMID- 4308709 TI - [Epidemiologic material from the study of Japanese encephalitis in the Primorsk area in 1965]. PMID- 4308711 TI - [On the effect of adrenalectomy, adrenal hormones and ACTH on the resistance of developing rats to staphylococcal exotoxin and the endotoxin of Escherichia coli]. PMID- 4308710 TI - [An electron microscopic study of Cl. perfringens in the process of toxin formation]. PMID- 4308712 TI - [A study of the soluble antigens of strains of Cl. perfringens isolated from the feces of healthy persons]. PMID- 4308713 TI - Diurnal variations of the plasma cortisol level in diabetes insipidus. PMID- 4308714 TI - [Pathological study of familial primary amyloidosis with peripheral and autonomic nervous disorders as a main symptom, with special reference to 2 autopsy cases and literature review]. PMID- 4308715 TI - Coumarin-induced skin necrosis in a sixteen-year-old girl. PMID- 4308716 TI - Adenosine 3',5' monophosphate as an inhibitor of ovulation and reproduction. PMID- 4308717 TI - Study on the antituberculous activity of tuberactinomycin, a new antimicrobial drug. PMID- 4308718 TI - Nicotinamide adenine dinucleotide levels and nadase activity in polymorphonuclear leukocytes, alveolar macrophages, and erythrocytes of tuberculous guinea pigs. PMID- 4308719 TI - [Preparation of glucose-6-phosphate uniformly labeled with 14C]. PMID- 4308720 TI - A naturally occurring indolylpteridine. PMID- 4308721 TI - Binding of adenosine 5'-monophosphate and substrate by rabbit liver fructose 1,6 diphosphatase. PMID- 4308722 TI - Chemical structure of the insoluble hyphal wall glucan of Phytophthora cinnamomi. PMID- 4308723 TI - The rates of binding of reduced nicotinamide-adenine dinucleotide analogs to liver alcohol dehydrogenase. PMID- 4308724 TI - The fructose 1,6-diphosphatase of Dictyostelium discoideum. PMID- 4308725 TI - Regulation of the activity of L-aspartate beta-decarboxylase by a novel allosteric mechanism. PMID- 4308726 TI - Phosphoramidates. V. Probable identity of rat liver microsomal glucose 6 phosphatase, phosphoramidase, and phosphoramidate-hexose phosphotransferase. PMID- 4308727 TI - Different allosteric properties of nucleoside diphosphatase isoenzymes from rat liver. PMID- 4308729 TI - Abnormal height in children. PMID- 4308731 TI - [The effect of depancreatization on the function of the myoneural synapse in frogs]. PMID- 4308730 TI - The regulation of glycolysis in mammalian erythrocytes. PMID- 4308732 TI - [On the role of gluco-and mineralocorticoids in the regulation of sucrose hydrolysis and enzyme synthesis in the small intestine]. PMID- 4308734 TI - Ca2+ uptake and acetyl phosphatase of skeletal muscle microsomes. Inhibition by Na+, K+, Li+, and adenosine triphosphate. PMID- 4308735 TI - Isolation, morphology, and composition of the nuclear membrane from rat liver. PMID- 4308733 TI - Hormones and cholesterol ester metabolism. PMID- 4308736 TI - Action of micrococcal nuclease on polymers of deoxyadenylic and deoxythymidylic acids. PMID- 4308737 TI - Studies on the kinetic mechanism and allosteric nature of bovine brain hexokinase. PMID- 4308738 TI - The regulation of rat liver xanthine oxidase. Conversion in vitro of the enzyme activity from dehydrogenase (type D) to oxidase (type O). PMID- 4308739 TI - An experimental approach to the study of the folding of staphylococcal nuclease. PMID- 4308740 TI - Structural studies on polypeptide hormones. I. Fluorescence. PMID- 4308741 TI - Evidence for an internal antigen in foot-and-mouth disease virus. PMID- 4308743 TI - [Histochemical study in changes of phenotype of cancer cells--biological properties and enzyme histochemical findings of AH13 in vivo and in vitro]. PMID- 4308742 TI - Malignant myoblastoma. A case report. PMID- 4308744 TI - Neurocutaneous melanosis and melanomas in children. PMID- 4308745 TI - [Early diagnosis and treatment of hypertension and renal vascular hypertension]. PMID- 4308746 TI - Cytomegalovirus infection of the cervix: an "incidental" finding of possible clinical significance. Report of a case. PMID- 4308747 TI - Prediction of outcome of pregnancy by vaginal cytology. Evaluation of the "estrogen test". PMID- 4308748 TI - Herpes vulvitis. PMID- 4308749 TI - [Biosynthesis and metabolism of nicotinamide adenine dinucleotide in the brain]. PMID- 4308751 TI - [Research on the reactivation of phosphatase and the possibilities of reuse of a solid substrate with p-nitrophenylphosphate]. PMID- 4308750 TI - [Evolution of enzymatic acivities of rat liver preserved in deep cold]. PMID- 4308752 TI - [Nontumorous stenoses and obstructions of the aqueduct of Sylvius]. PMID- 4308754 TI - [Levels of urinary 6-beta-hydroxycortisol and other polar corticosteroids in children with severe diseases and its fluctuation by ACTH loading]. PMID- 4308753 TI - [A case of severe cresol poisoning]. PMID- 4308755 TI - [Levels of urinary 6-beta-hydrocortisol and other polar corticosteroids in healthy children and its fluctuation by ACTH loading]. PMID- 4308756 TI - [Mixed mesodermal tumor of the uterus]. PMID- 4308757 TI - [Experimental study of the antitumor activity of an antibiotic isolated from Actinomyces fumigatus]. PMID- 4308758 TI - [ESR studies on x-irradiated salts of leucine. II. Radical yield and radical kinetics in irradiated L-leucine-HCl]. PMID- 4308759 TI - [Age and rate of ossification of the distal epiphyseal cartilages of the leg bones in young males]. PMID- 4308760 TI - [Behavior of the diaphorase of coenzyme I (NAD) during degeneration of the sciatic nerve in hooded rats after nerve freezing]. PMID- 4308761 TI - [The role of renin in the pathophysiology and diagnosis, excluding pregnancy and its complications]. PMID- 4308763 TI - [Cytomegalovirus infection, with special reference to primary infection in infants]. PMID- 4308762 TI - [Treatment of pulmonary tuberculosis in patients resistant to major drugs with second line drugs]. PMID- 4308764 TI - Systematic transference interpretations in the sleep laboratory. A new approach to psychoanalytic research. PMID- 4308765 TI - [Determination of antitumor activity in rat ascites hepatomas by agar diffusion technique]. PMID- 4308766 TI - [Changes in renal hemodynamics and function in cardiac insufficiency]. PMID- 4308767 TI - [Effects of streptomycin-resistance of Mycobacterium tuberculosis on induction rate of resistance to kanamycin, viomycin and capreomycin and on cross-resistance among these drugs]. PMID- 4308768 TI - [Inactivation of hemagglutinating activity of HVJ hemagglutinating virus of Japan with sulfhydryl compounds and sodium borohydride]. PMID- 4308769 TI - [Genetics in ophthalmology (a review of the foreign literature)]. PMID- 4308770 TI - [Case of cylindroma (adenoid cystic carcinoma) of the external auditory canal]. PMID- 4308771 TI - [Clinical symptoms of malignant synovioma]. PMID- 4308772 TI - [Adrenal gland function in thyrotoxicosis]. PMID- 4308773 TI - [Some problems of the effect of irradiation of the diencephalo-hypophyseal region in the pathological state on the endocrine glands]. PMID- 4308775 TI - [Condition of carbohydrate metabolism in the initial and atypical forms of Itsenko-Cushing disease]. PMID- 4308776 TI - [ACTH and pituitary-adrenal system]. PMID- 4308774 TI - [Pathogenetic mechanism of diabetes insipidus and the problems of its therapy]. PMID- 4308778 TI - [The significance of the liver in the regulation of fractional composition of ll oxycorticosteroids of blood plasma]. PMID- 4308777 TI - [The effect of the adrenal cortex hormones on adrenalin synthesis in the adrenal glands of chick embryos and chicks]. PMID- 4308779 TI - [Chemical synthesis of proteins]. PMID- 4308780 TI - [Study of the megakaryocyte system in hepato-splenic schistosomiasis]. PMID- 4308781 TI - Free radicals in bone grafts sterilized by ionizing radiation. PMID- 4308782 TI - [The microflora of the small intestine of patients with chronic colitis before and after complex treatment in the Essentuki health resort]. PMID- 4308783 TI - Experimental peritonitis in irradiated rabbits. PMID- 4308784 TI - Massive gangrene of the colon secondary to carcinoma of the rectum. Case report. PMID- 4308787 TI - Exfoliative cytopathologic studies in organ transplantation. I. The cytologic diagnosis of cytomegalic inclusion disease in the urine of renal allograft recipients. PMID- 4308786 TI - Morphologic and pathologic aspects of intercalated disc of the heart. PMID- 4308788 TI - Lymphatic and visceral irradiation from endolymphatic infusion in the rabbit. PMID- 4308785 TI - Quantitative aspects of lipolysis and reesterification in human adipose tissue in vitro. PMID- 4308789 TI - Serial brain scanning with technetium 99m and scintillation camera. PMID- 4308790 TI - Liver and spleen scintiscanning with indium 113m. A clinical pathologic correlation. PMID- 4308792 TI - Roentgenologic manifestations of malignant tumors of the nasopharynx. PMID- 4308791 TI - Liver irradiation in children: acute changes with transient leukopenia and thrombocytopenia. PMID- 4308793 TI - Treatment of cancer of the nasal cavity. PMID- 4308794 TI - The diagnostic problems of isolated, circumscribed breast tumors. PMID- 4308795 TI - Stage 4 sleep in schizophrenia. PMID- 4308798 TI - Viral growth patterns in an iris organ culture system. PMID- 4308797 TI - Neuromuscular disorder following gastric resection. PMID- 4308796 TI - Effects of selected phenothiazines on REM sleep in schizophrenics. PMID- 4308799 TI - [Studies on the teratogenic effect of hydroxyurea during the early and embryonic development of mice]. PMID- 4308800 TI - A bovine strain of Myxovirus parainfluenza type 3. Experimental transmission and a survey of antibodies in cattle in Australia and New Guinea. PMID- 4308801 TI - The isolation of Myxovirus parainfluenza type 3 from sheep in Australia. PMID- 4308802 TI - [Kinetic investigation on the enzymatic hydroxylation of phenazone, oxidative O demethylation of codeine and N-demethylation of aminophenazone by rat liver microsomes]. PMID- 4308803 TI - Inhibition of ethanol metabolism in vivo by administration of pyrazole. PMID- 4308804 TI - Study on the stability of lysosome membranes. V. Changes in the stability of liver lysosomes of rats kept at different temperatures after treatment with chlorpromazine. PMID- 4308805 TI - Creutzfeldt-Jakob's disease: a histochemical study. PMID- 4308806 TI - Recurrent and chronic relapsing Guillain-Barre polyneuritis. PMID- 4308807 TI - Control by brain stem reticular formation of sensory transmission in Burdach nucleus. Analysis of single units. PMID- 4308808 TI - Mechanism of the effects of furosemide on renin secretion in anesthetized dogs. PMID- 4308809 TI - Non-carcinogenicity of hexamethylenetetramine in mice and rats. PMID- 4308810 TI - [Comparative study of metabolic disturbances in the rat liver caused by administration of ethanol or other substances. I. Effect of an intraperitoneal injection of ethanol]. PMID- 4308811 TI - Carcinogenicity of ponceau MX in the mouse. PMID- 4308812 TI - A case of metastatic carcinoma of choroid from breast. PMID- 4308814 TI - Pastes on normal and "white-spot" enamel. The effect of fluoride-containing prophylaxis. PMID- 4308813 TI - Labortary studies concerning the development of a stannous fluoride-phosphate prophylactic paste. PMID- 4308815 TI - [The function of the lateral geniculate body]. PMID- 4308816 TI - [The 3d factor and associated problems]. PMID- 4308817 TI - [Bartter's syndrome--case report and literature review]. PMID- 4308818 TI - [A case of simultaneous bilateral mixed tumor of the parotid gland]. PMID- 4308821 TI - A sibship with Bartter's syndrome: failure of total adrenalectomy to correct the potassium wasting. PMID- 4308819 TI - [5-year follow-up of treatment of mesodermal mixed tumors and uterine carcinosarcomas]. PMID- 4308820 TI - My field of research--cell malignancy in vitro. PMID- 4308822 TI - Malignant hepatoma presenting as a spinal lesion. PMID- 4308823 TI - Aplasias of the anterior thoracic wall, the pectoral muscles, and the breast. PMID- 4308824 TI - [Changes in the activity of mitochondrial enzymes under experimental liver ischemia]. PMID- 4308825 TI - [Changes in enzyme activity of mitochondria, endoplasmic reticulum and lysosomes during liver regeneration]. PMID- 4308826 TI - [Polyneuritis--polyradiculitis--polyneuropathy]. PMID- 4308828 TI - [The polyneuropathies]. PMID- 4308827 TI - [Neuropathological aspects of polyneuritis and polyneuropathies]. PMID- 4308829 TI - [EMG studies of peripheral nerve diaeases]. PMID- 4308830 TI - Human liver alcohol dehydrogenase: inhibition by pyrazole and pyrazole analogs. PMID- 4308832 TI - Studies on plasma angiotensinase activity in normal and toxemic pregnancy. PMID- 4308831 TI - Studies on the stereospecificity of liver alcohol dehydrogenase (LADH) for 3beta hydroxy-5beta-steroids. Inhibition effect of pyrazole and of a 3alpha hydroxycholanoic acid. PMID- 4308834 TI - Histochemical observation on the phosphatase activities of the differentiating taste bud. PMID- 4308833 TI - Serum ornithine carbamoyl transferase activity (S-OCT) after irradiation of malignant tumours and after administration of ACTH. PMID- 4308835 TI - [Contribution to the demonstration of some therapeutically applied salicylamide derivatives on silica gel layers]. PMID- 4308836 TI - [Infectious rhinotracheitis virus (IBR) and Mycoplasma in cattle]. PMID- 4308837 TI - Regulation of glycolysis and L-glycerol 3-phosphate concentration in rat epididymal adipose tissue in vitro. Role of phosphofructokinase. AB - 1. Attempts were made to define the role of phosphofructokinase in glycolytic control and the factors regulating the concentration of l-glycerol 3-phosphate in rat epididymal fat pads incubated in vitro. 2. Glycolysis rates were altered by anoxia or by additions of insulin, adrenaline or both to the incubation medium, and the changes in rate were related to changes in the steady-state concentrations of hexose phosphates, adenine nucleotides, l-glycerol 3-phosphate and citrate in the whole tissue. Measurements were also made of the lactate/pyruvate concentration ratio in the medium after incubation. 3. The mass action ratios of phosphofructokinase, calculated from the whole-tissue concentrations of products and substrates, were less than 0.1% of the value of the ratio at pH7.4 at equilibrium. 4. Only in the presence of adrenaline could the observed stimulation of glycolytic flux be related to a possible activation of phosphofructokinase since, in this situation, the concentration of one substrate, fructose 6-phosphate, was not altered and the concentration of the other, ATP, was decreased. Increased glycolytic flux in the presence of insulin may be explained by an observed increase in the concentration of the substrate, fructose 6-phosphate. Under anaerobic conditions, glycolytic flux was decreased but this did not appear to be the result of inhibition of phosphofructokinase, since the concentrations of both substrates, fructose 6-phosphate and ATP, were decreased. The changes in glycolytic flux with insulin and anoxia may be secondary to changes in the rate of glucose uptake. 5. Changes in l-glycerol 3 phosphate concentration appear to be related both to changes in the concentration of dihydroxyacetone phosphate and to changes in the NADH/NAD(+) concentration ratio in the cytoplasm. They do not seem to be related directly to alterations in glycolytic rate. PMID- 4308838 TI - Metabolism of camphors and related compounds. AB - 1. The metabolism of (+/-)-norcamphor, (+)-camphor, (-)-camphor, (+)-epicamphor, (+/-)-camphorquinone, (+/-)-camphane-2,5-dione and camphane was investigated in rabbits. All the compounds except camphane-2,5-dione increased the content of glucuronide in the urine. 2. (+/-)-Norcamphor was reduced to endo-norborneol; (+) camphor, contrary to expectation, was reduced to (+)-borneol, as well as being hydroxylated to (+)-5-endo-hydroxycamphor and (+)-3-endo-hydroxycamphor, 5-endo hydroxycamphor being the predominant product. (+)-Epicamphor was reduced mainly to (+)-epiborneol; (+/-)-camphorquinone gave 3-endo-hydroxycamphor and 2-endo hydroxyepicamphor, the former being the major metabolite. (+/-)-Camphane-2,5 dione was reduced to 5-endo-hydroxycamphor. Camphane was hydroxylated to borneol and epiborneol, the latter predominating. 3. An explanation of these findings is given in terms of steric hindrance and thermodynamic stability. 4. The possibility was investigated that NADH was involved in the reductions. PMID- 4308840 TI - Persistent respiratory virus infection in tracheal organ cultures. PMID- 4308839 TI - Some enzymic activities and chemical properties of the mesosomes and cytoplasmic membranes of Bacillus licheniformis 6346. AB - 1. The liberation of the vesicles of the mesosomes from protoplasts of Bacillus licheniformis strain 6346 is controlled by the Mg(2+) concentration present during the removal of the walls by lysozyme. 2. The functioning of the cytoplasmic membranes is also critically controlled by the Mg(2+) concentration. 3. The isolated mesosomes and the cytoplasmic membranes differ in their enzymic activities. Both succinate dehydrogenase and NADH oxidase activities are very low or absent from the mesosomes. 4. The cytoplasmic membranes can also be separated into materials of different density. 5. Distribution of the membranes between these fractions is controlled by the Mg(2+) concentration and the growth conditions of the microorganisms. PMID- 4308841 TI - Physiologic control of arterial pressure. PMID- 4308842 TI - Renal and adrenal factors in hypertension: diagnostic approaches. PMID- 4308843 TI - [New knowledge about the physiology of sleep]. PMID- 4308844 TI - Composition of rat liver triacylglycerols and diacylglycerols. PMID- 4308845 TI - Biosynthesis of 6 beta- and 6 alpha-hydroxyprogesterone in the human foetal liver. PMID- 4308847 TI - [Antiviral potentials. XI. Pyrimidine derivatives]. PMID- 4308846 TI - [Biosynthesis of sterols in tobacco tissues cultivated in vitro. Kinetics of the formation of sterols and their precursors]. PMID- 4308848 TI - [Studies on renin in normal pregnancy]. PMID- 4308849 TI - Enzyme histochemistry and hormones of the developing gastrointestinal tract of the chick embryo. I. A histochemical and quantitative study of glycogen, uridine diphosphate glucose-glycogen transglucosylase, glucose-6-phosphatase and phosphorylase. PMID- 4308850 TI - Further cytochemical studies of the mucopolysaccharides of the test cells of Ciona intestinalis L. PMID- 4308851 TI - [Studies on the enzymatic specificity of neuraminidase and N-acyl neuraminatelyase in relation to N-substitution]. PMID- 4308852 TI - Studies on the occurrence and properties of lysosomal phospholipases A1 and A2 and the degradation of phosphatidic acid in rat liver lysosomes. PMID- 4308853 TI - [Change in the optical rotatory dispersion of lactate dehydrogenase from pig heart muscle after addition of urea, coenzyme and SH-blocking reagents]. PMID- 4308854 TI - Affinity labeling of the active site of staphylococcal nuclease. Reactions with bromoacetylated substrate analogues. PMID- 4308855 TI - Purification and partial characterization of the aminoacyl transfer ribonucleic acid binding enzyme from rabbit reticulocytes. PMID- 4308856 TI - Porcine heart lactate dehydrogenase. Optical rotatory dispersion, thermodynamics, and kinetics of binding reactions. PMID- 4308857 TI - Lipid peroxidation in vitro by isolated fat cells of rats. Correlation with total lipolysis, glucose utilization, and dietary tocopherol. PMID- 4308858 TI - Reduction of alpha-ketoglutarate by homogeneous lactic dehydrogenase X of testicular tissue. PMID- 4308859 TI - Structural studies on polypeptide hormones. II. Polarization of fluorescence. PMID- 4308860 TI - Energy-linked ion translocation in submitochondrial particles. I. Ca++ accumulation in submitochondrial particles. PMID- 4308861 TI - Coenzyme A- and nicotinamide adenine dinucleotide-dependent branched chain alpha keto acid dehydrogenase. I. Purification and properties of the enzyme from Bacillus subtilis. PMID- 4308863 TI - Amino acid transport by isolated mammalian renal tubules. II. Transport systems for L-proline. PMID- 4308862 TI - Cyclic guanosine 3',5'-monophosphate in mammalian tissues and urine. PMID- 4308864 TI - Organization of inhibition in abdominal ganglion of Aplysia. I. Role of inhibition and disinhibition in transforming neural activity. PMID- 4308865 TI - Organization of inhibition in abdominal ganglion of Aplysia. II. Posttetanic potentiation, heterosynaptic depression, and increments in frequency of inhibitory postsynaptic potentials. PMID- 4308866 TI - Organization of inhibition in abdominal ganglion of Aplysia. 3. Interneurons mediating inhibition. PMID- 4308867 TI - Some quantitative aspects of pyramidal collateral inhibition. PMID- 4308868 TI - Effects of eye movement, brain-stem stimulation, and alertness on transmission through lateral geniculate body of monkey. PMID- 4308869 TI - The use of 5-iodo-2'-deoxyuridine (IUDR) in Orabase and plastibase for treatment of oral herpes simplex. PMID- 4308871 TI - Role of angiotensin in normal blood pressure regulation. PMID- 4308870 TI - [The influence of the adrenal cortex on adrenaline synthesis in the rat and rabbits fetus and neonate]. PMID- 4308872 TI - [Immune mechanism in neoplastic diseases]. PMID- 4308873 TI - [Retroperitoneal fibroendotheliohistiocytoma demonstrating insulin activity as a cause of severe hypoglycemic episodes]. PMID- 4308874 TI - The synthesis of deoxyribonucleic acid and nuclear proteins by rat hepatoma cells immediately after gamma irradiation. PMID- 4308875 TI - ESR-studies of normal and 5-bromouracil-substituted DNA of Bacillus subtilis after irradiation with ultraviolet light. PMID- 4308876 TI - The reaction of hydrogen atoms with DNA. PMID- 4308877 TI - Experimental infection of calves with bovine adenovirus types 1 and 2. PMID- 4308878 TI - Failure of chicken antisera against porcine enterovirus strain V13 to neutralized at low dilutions. PMID- 4308879 TI - Heat inactivation of foot-and-mouth disease virus in blood products. PMID- 4308880 TI - [On a congenital epulis (apropos of an unusual personal finding)]. PMID- 4308881 TI - [Considerations on the treatment of thyroid cancer]. PMID- 4308882 TI - [Study of the perchlorosoluble protein fraction of the normal and pathological arterial wall]. PMID- 4308883 TI - [Iatrogenic digestive system diseases]. PMID- 4308884 TI - [Mixed tuberculosis: pulmonary and associated extrapulmonary tuberculosis of adults]. PMID- 4308885 TI - [The daytime hospital for psychiatric disorders. Presentation of some current french realizations]. PMID- 4308886 TI - 3-amino-proline from viomycidine. PMID- 4308887 TI - [Preventing diseases of the peripheral nervous system among troops]. PMID- 4308888 TI - [Low frequency impulse currents in therapeutic practice]. PMID- 4308890 TI - Quantitative histochemical analysis of cytomegalic nuclear inclusions. PMID- 4308889 TI - [On enzyme defects of the gastrointestinal tract]. PMID- 4308891 TI - Proliferation of mast cells in peripheral nerves during Wallerian degeneration. A radioautographic study. PMID- 4308892 TI - Ultrastructural study of a nerve biopsy from a case of early infantile chronic neuropathy. PMID- 4308893 TI - Electron microscopic observations in mice infected with Japanese encephalitis. PMID- 4308894 TI - Psychological, psychophysiological, and biochemical correlates of prolonged sleep deprivation. PMID- 4308896 TI - [Comparative study of the in vitro cytotoxic activity, lecithinase activity and lethality in mice of Clostridium welchii alpha-toxin]. PMID- 4308895 TI - [Comparative study of RNA extracted from an attenuated and a virulent poliovirus]. PMID- 4308897 TI - Transmissible gastro-enteritis of swine (TGE). PMID- 4308899 TI - Behavior of sulfhydryl groups of yeast alcohol dehydrogenase for 5,5'-dithiobis(2 nitrobenzoic acid). PMID- 4308900 TI - [The treatment of spontaneous hypoglycemia in inoperable liver cell carcinoma with glucagon]. PMID- 4308901 TI - [Antiviral potentials. 13. Heterocyclic thiosemicarbazones]. PMID- 4308898 TI - [Bacterial resistance to antibiotics in Quebec: study with enterobacteria]. PMID- 4308902 TI - Peptide-secreting tumours with special reference to the pancreas. PMID- 4308903 TI - Effects of corticosteroids on mouse hepatitis virus infection. PMID- 4308904 TI - [2,3-diphosphoglycerate metabolism and glycolysis in human erythrocytes. Influence of sulfate, tetrathionate and disulfite]. PMID- 4308906 TI - Allosteric and kinetic properties of a K-dependent acylphosphatase in rat brain synaptosomes and its possible relation to (Na+K) ATPase. PMID- 4308905 TI - [Changes in the activity o some microsomal liver enzymes following phalloidin poisoning in rats]. PMID- 4308907 TI - Apparent low levels of ubiquinone in rat and human neoplastic tissues. PMID- 4308908 TI - Homogeneity and sequential periodate oxidation of a glycopeptide from Taka amylase A. PMID- 4308909 TI - Electron paramagnetic resonance study of bovine liver catalase. PMID- 4308910 TI - Isolation of a synaptic vesicle fraction from guinea pig brain with the use of DEAE-sephadex column chromatography and some of its properties. PMID- 4308911 TI - Failure of the cirrhotic liver to inactivate renin: evidence for a splanchnic source of renin-like activity. PMID- 4308912 TI - An enzymatic method for the measurement of asparagine and a new assay of asparaginase activity. PMID- 4308913 TI - Fate of Sendai virus ribonucleoprotein in virus-infected cells. AB - The cytoplasmic extracts of Ehrlich ascites tumor cells infected with (32)PO(4) and (3)H-leucine-labeled Sendai virus have been examined during the course of infection with respect to sedimentation behavior and buoyant densities of input virus radioactivity. It was found that (32)P and (3)H radioactivities were coincident, and, at 30 min after infection, the bulk of radioactivity was recovered in the polysome region of a sucrose gradient in the position of Sendai virus ribonucleoprotein (210S). The heterogeneity of radioactivity profiles appeared at 1 hr after infection and increased during 6 hr of incubation. The buoyant densities of input virus components were determined by banding in CsCl gradient. Here again the bulk of coincident (32)P and (3)H radioactivity at 30 min after infection banded at the same density as Sendai virus ribonucleoprotein (1.31 g/cm(3).) This component disappeared at 3 hr after infection, and (32)P and (3)H radioactivities were now found in components banded at densities 1.38, 1.41, 1.45, 1.49, and 1.55 g/cm(3). The results presented are consistent with the idea that virus ribonucleoprotein is retained in the cytoplasm of infected cells during at least 6 hr of incubation, being partly deproteinized in the course of infection. The nature of components which banded at rho = 1.41, 1.45, 1.49, and 1.55 as complexes of partly deproteinized ribonucleoprotein with ribosomes will be described in a separate paper. PMID- 4308914 TI - Relative sensitivities of viruses to different species of interferon. AB - Some viruses were found to be more sensitive than others to the action of interferons from certain species of animals but less sensitive to interferons from other species. Vaccinia virus was the most sensitive to mouse and hamster interferons of five viruses tested, but the least sensitive of these five viruses to human, rabbit, and bat interferons. The relative sensitivities of the viruses to interferons were found to be characteristic for each of the species tested, with those closely related phylogenetically exhibiting similar patterns of relative interferon-induced virus resistance. The amount of synthetic double stranded polynucleotide polyinosinic acid-polycytidylic acid required to induce resistance to each of the viruses in each of the cell species correlated with the interferon sensitivities of the viruses. PMID- 4308916 TI - Transitory free radicals in irradiated animal tissues. PMID- 4308915 TI - Ribonucleic acid synthesis of vesicular stomatitis virus. I. Species of ribonucleic acid found in Chinese hamster ovary cells infected with plaque forming and defective particles. AB - Plaque-forming B particles of vesicular stomatitis virus (VSV) induce the synthesis of virus-specific ribonucleic acid (RNA) in Chinese hamster ovary cells, whereas defective T particles do not. Infection with low input multiplicities of B results in the formation of four species of RNA. During infection with high multiplicities, RNA synthesis begins with mainly these four species of RNA but gradually shifts to a new pattern of RNA synthesis involving five other species of RNA. The change can also be induced by superinfection with T at 2.5 hr after infection with a low multiplicity of B. T added at the same time as B prevents virtually all RNA synthesis. Synthesis of the first group of RNA species correlates with the formation of B particles, whereas synthesis of the second group correlates with the formation of T particles. The various species of RNA formed after infection with VSV particles include single-stranded RNA, a completely double-stranded RNA, and RNA with partially double-stranded regions. These observations begin to establish a molecular basis for understanding the ability of T particles to interfere with the growth of B particles. PMID- 4308917 TI - Histochemical studies on the effect of nerve impulses on exogenous catecholamines taken up into the adrenergic nerves of reserpine-pretreated animals. PMID- 4308919 TI - An E.P.R. study of peptides after U.V. irradiation. PMID- 4308918 TI - On the mechanism of the neuromuscular blocking action of cobalt ion. PMID- 4308920 TI - [Cytochemical studies on epithelium of renal tubuli in experimental conditions]. PMID- 4308921 TI - [The sequelae of hypoglycemia in patients with diabetes mellitus]. PMID- 4308922 TI - [The activity of nonspecific phosphatases of the thyroid gland in diffuse toxic goiter and thyrotoxic adenoma]. PMID- 4308924 TI - [Enteroviruses observed with electron microscope in biopsies of malignant tumors in dog]. PMID- 4308923 TI - [Biosynthesis of ACTH and somatotropin in rat hypophyses following prednisolone block, immobilization and starvation]. PMID- 4308925 TI - [The neoantigens of cancer cells and their significance]. PMID- 4308927 TI - [On the problem of involution of juvenile angiofibroma of the nasopharynx]. PMID- 4308926 TI - Duration of application and change of a regimen with secondary drugs. PMID- 4308928 TI - [Fine structure and genesis of cylindroma adenoidcystic carcinoma of the salivary glands. Further investigations on the role of myoepithelial differentiated cells in salivary gland tumors]. PMID- 4308929 TI - [Is it necessary to perform surgery on cancer metastases to the brain? (Review of the literature)]. PMID- 4308930 TI - [Use of laky blood in diseases of the peripheral nervous system]. PMID- 4308931 TI - [Apropos of the effect of roentgen irradiation on tryptophan pyrrolase and NAD]. PMID- 4308932 TI - [Importance of selective arteriography in the diagnosis of langerhansian carcinoma. Apropos of a case]. PMID- 4308933 TI - Intracellular pO2 control on excitability and synaptic activability in aplysia and helix identifiable giant neurons. PMID- 4308934 TI - Influence of statolon on resistance of mice to influenza. AB - Various interferon inducers are known to elicit protection against lethal or infecting doses of certain viral agents. Because of the relatively high morbidity rate of influenza and its seasonal occurrence, we wished to determine whether statolon-induced interferon might be effective in controlling this disease. Mice were treated intraperitoneally with statolon and challenged with influenza A(2) virus by the intranasal route. Although interferon was present in the serum at the time of virus administration, no change in mortality rate was observed. There was, however, a significant increase in the mean survival time of treated animals. Similar results were obtained when Newcastle disease virus was used as the interferon inducer. To determine the effect of the route of challenge, other mice were treated with statolon or Newcastle disease virus and inoculated with mengovirus by the intranasal or intraperitoneal route. The results demonstrated that the treated mice were protected to similar degree against challenge by either route. It is suggested that the relative ineffectiveness of interferon in protecting mice against influenza is due to an intrinsic characteristic of the virus itself rather than the type of interferon induced or the route of virus challenge. PMID- 4308936 TI - Preparation of primary bovine corneal epithelial cell cultures for use in virological investigations. AB - Primary and secondary cell cultures in sufficient quantity for use in virological investigations were prepared and were found suitable for growth of animal viruses. PMID- 4308935 TI - Response of white mice to cells and culture constituents of Clostridium perfringens. AB - Broth cultures of Clostridium perfringens (ATCC 10543) were fractionated by ammonium sulfate precipitation and Sephadex G-150 chromatography. Components isolated, as well as some enzymes present in the culture, were assayed for toxicity by feeding to white mice. Early work indicated that when a meat-fat starch slurry, infected with C. perfringens, was fed to mice, the intestinal passage time was reduced. By using large numbers of mice as test animals and analyzing the data statistically, we found that C. perfringens and several fractions from the culture supernatant significantly affected the mice. A toxic material present in the supernatant was not identifiable as phospholipase C. Phospholipase C and physphorylcholine affected the intestinal passage time of the mice only when large amounts were given. The enzyme, neuraminidase, and another unidentified compound present in the supernatant affected the passage time when very small amounts were fed to mice. PMID- 4308937 TI - Some morphologic, biologic and metabolic properties of transplantable Kirkman Robbins hepatoma in hamsters. PMID- 4308939 TI - Transmission of labyrinthine volleys through the vestibular nuclei during sleep. PMID- 4308938 TI - The effect of thiazide on the sympathetic nervous system of hypertensive rats. PMID- 4308940 TI - [Cytomegaly in a patient with reticulosarcomatosis and diabetes mellitus]. PMID- 4308942 TI - [Cancer and glomus tumor of the stomach]. PMID- 4308941 TI - [Morphology of the ovaries in mice after general single dose of x-ray irradiation]. PMID- 4308943 TI - [Histoenzymochemical study of autopsy material]. PMID- 4308944 TI - The biosynthesis of terpenoid quinones. PMID- 4308945 TI - Induction of lipase and phytase activities in the aleurine tissue of germinating wheat grains. PMID- 4308946 TI - The structural organization of haem synthesis in rat liver mitochondria. AB - 1. Anaerobic conditions are normally necessary for incorporation of iron into haems and only ferrous iron is used. After addition of succinate to an incubation mixture containing intact or ultrasonically treated mitochondria, Fe(3+) is used, but only if no inhibitors prevent the transfer of electrons from the mitochondrial respiratory chain to oxygen. 2. A dual-wavelength spectrophotometric assay for ferrochelatase is described that has been used for the continuous assay of incorporation of metal ions into porphyrins. Constants are given for the determination of rates of formation of protohaem and cobalt protoporphyrin, mesohaem, cobalt mesoporphyrin and zinc mesoporphyrin. For cobalt mesoporphyrin formation the K(m) for Co(2+) is 11x10(-6)m and that for mesoporphyrin is 5x10(-6)m. 3. An improved method for the separation of inner and outer membranes of mitochondria is described. Mitochondria swollen in hypo osmotic media were contracted in hyperosmotic potassium chloride solution containing ATP and the outer membranes detached by mild ultrasonic treatment. Sucrose inhibited the ATP-induced contraction and decreased the yield of outer membranes. 4. Ferrochelatase is associated with cytochrome oxidase, which is used as a marker for inner mitochondrial membranes. 5. By using as substrate porphyrin dissolved in phospholipid micelles, ferrochelatase activity of intact mitochondria was shown to be latent, and to be liberated by ultrasonic treatment. 6. No ferrochelatase was detectable in microsomes or soluble cell components. PMID- 4308947 TI - [Programs of prevention recently applied in the Ivory Coast]. PMID- 4308948 TI - [Swine adenovirus]. PMID- 4308950 TI - [Epizootiology of equine plague in Spain]. PMID- 4308949 TI - [Diagnosis of equine plague in Spain]. PMID- 4308951 TI - [Notes on African horse-sickness in Tunisia]. PMID- 4308952 TI - Autogenous and virus-induced interferons from lines of lymphoblastoid cells. PMID- 4308953 TI - Thymidine phosphate pools and DNA synthesis after polyoma infection of mouse embryo cells. PMID- 4308954 TI - An antiserum to ovarian mucinous cyst fluid with colon cancer specificity. PMID- 4308955 TI - Increased DNA polymerase activity in a series of rat hepatomas. PMID- 4308956 TI - Separation of DNA polymerase from rat liver and hepatomas. PMID- 4308957 TI - A role for nicotinamide adenine dinucleotide glycohydrolase in the control of glyceraldehyde-3-phosphate dehydrogenase activity. PMID- 4308960 TI - [Quantitative determination of stereoisomers of vitamin A on the basis of extinction gradient-method]. PMID- 4308958 TI - Effect of Rous sarcoma virus infection on recovery of nucleolar RNA, ribonucleoprotein, and DNA synthesis from inhibition by actinomycin D. PMID- 4308959 TI - [Metabolite content and enzyme permeability of isolated human blood cells without substrate and with addition of metabolic poisons]. PMID- 4308961 TI - Application of the fluorescent antibody method in the diagnosis of M. parainfluenzae. II. Identification of newly isolated m. parainfluenzae strains in monkey kidney tissue cultures. PMID- 4308962 TI - Identification of the Motol virus. 2. Relationship to pox viruses. PMID- 4308964 TI - [Effects of parathyroid hormone on the microsomal functions of rat kidney]. PMID- 4308963 TI - Polymyositis presenting as distal muscle weakness. A case report. PMID- 4308965 TI - [Studies on renal hypertension. VI: Studies on renal angiotensinase]. PMID- 4308966 TI - Melatonin and its precursors' effects on 131-I uptake by the thyroid gland under different photic conditions. PMID- 4308968 TI - [Study of the vitamin nutrition of Bac. polymyxa Ross, a polymyxin M producer]. PMID- 4308967 TI - Sleep deprivation: changes of monoamines and acetylcholine in rat brain. PMID- 4308970 TI - [Influence of agar cover composition on the capacity of the poliomyelitis virus to form plaques]. PMID- 4308969 TI - [Study of the effect of Cl. sporogenes proteinases on the hemolytic activity of Cl. perfringens type A toxin]. PMID- 4308971 TI - [Comparative light-and electron microscopic studies on the communicable venereal sarcoma and histiocytoma of the dog]. PMID- 4308972 TI - [Changesi peroxidse nd cytochrome oxidase in the neutrophils in Botkin's disease in children]. PMID- 4308973 TI - [On the gel formation with highly dispersed silica dioxide]. PMID- 4308974 TI - [The effects of ACTH and glucocorticoids on evacuatory function of the stomach in dogs]. PMID- 4308975 TI - [Current views on the mechanism of cellular action of antidiuretic hormone (review of the literature)]. PMID- 4308977 TI - Effect of living and non-living BCG on translocation of quartz dust from the lungs to their regional lymph nodes. An experimental study on rats. PMID- 4308976 TI - [Urinary testosterone and epitestosterone in gynecology practice]. PMID- 4308978 TI - Effect of BCG on translocation of quartz dust from the lungs to their regional lymph nodes after different BCG and quartz dose. An experimental study on rats. PMID- 4308979 TI - Effect of variations in time interval between treatment with BCG and quartz dust on translocation of quartz dust from the lungs to their regional lymph nodes. An experimental study on rats. PMID- 4308980 TI - [Some reflections on Cushing's disease]. PMID- 4308981 TI - [Basedowified goiters]. PMID- 4308982 TI - [Serum enzymes in coronary disease. Clinical value of alpha-hydroxybutyric dehydrogenase]. PMID- 4308983 TI - [Recto-colic melanosis]. PMID- 4308984 TI - [Laparoscopic study of the lymphatic vessels of the small intestines]. PMID- 4308985 TI - [Efficacy of an anti-edema agent in surgery]. PMID- 4308986 TI - [Stenosis of 3 abdominal visceral arteries compared by a new measuring technique at autopsy]. PMID- 4308987 TI - [Megaloblastic anemia with macroglobulinemia in a cirrhotic gastrectomized patient]. PMID- 4308988 TI - [Infrastructural aspects of the traversal of migrating cells throught the alveolar wall of the lung]. PMID- 4308989 TI - Participation of the cell membrane in the formation of "autophagic vacuoles". PMID- 4308990 TI - Autophagocytosis: origin of membrane and hydrolytic enzymes. PMID- 4308992 TI - [On the occurrence of Clostridium perfringens in healthy cattle for slaughter]. PMID- 4308991 TI - [On problems of biochemical changes during muscle activity]. PMID- 4308993 TI - Ultrastructure of synaptic terminals in nucleus infundibularis and nucleus supraopticus of Passer domesticus. PMID- 4308994 TI - [Ultrastructure and histochemistry of the pharyngeal cuticle of Eulalia viridis (Muller) (Polychaeta Errantia, Phyllodocidae) and its relationships with the subjacent epithelium in the digestive cycle]. PMID- 4308995 TI - Vascular reactions after experimental nerve section, suture, and transplantation. PMID- 4308997 TI - Effect of 5-hydroxytryptamine on experimental silicosis in the rat. PMID- 4308996 TI - Effect of reserpine and other drugs on the monoamine metabolism with special reference to the CNS. PMID- 4308998 TI - Conjugated estrogens (Premarin) for spontaneous and surgical bleeding. PMID- 4308999 TI - Substances with antineoplastic activity. 28. Cytostatic and pharmacologic properties of beta-4-methoxybenzoyl-beta-bromacrylic acid sodium salt. PMID- 4309000 TI - Viral infections of female genital tract. PMID- 4309001 TI - Jaundice, ascites, and hepatomegaly. Recurrence in Chinese male. PMID- 4309002 TI - Intermittent peritoneal dialysis. A study of medical complications occurring in 16 patients. PMID- 4309003 TI - Lymphangiography in the evaluation of malignant neoplasms. PMID- 4309004 TI - Effect of aminogluthethymide on urinary excretion of corticotropin and adrenal hormones. PMID- 4309005 TI - The rheumatoid factor and antinuclear antibodies in patients with viral hepatitis. PMID- 4309006 TI - Quantitative studies on the lipolytic response of human subcutaneous and omental adipose tissue to noradrenaline and theophylline. PMID- 4309007 TI - Cytomegalovirus infection among renal allograft recipients. PMID- 4309008 TI - Teratoma of the orbit. PMID- 4309009 TI - [Distribution of hemagglutination inhibition of Japanese encephalitis among inhabitants of the Takatsuki District]. PMID- 4309011 TI - Congenital cytomegalovirus infection associated with multicystic kidney. PMID- 4309010 TI - Hypertelorism, microtia, and facial clefting. A newly described inherited syndrome. PMID- 4309012 TI - The role of collagenase in the alkali-burned cornea. PMID- 4309013 TI - [Metastatic pleurisy in pancreatic cancer with the presence of considerable quantities of amylase in the pleural effuson and a major paraneoplastic peripheral neurologic syndrome]. PMID- 4309014 TI - The precursor of the evoked spindle activity during low voltage fast sleep. PMID- 4309015 TI - Changing concepts in Crohn's disease. PMID- 4309016 TI - Bioassay of parathyroid hormone in vitro with a stable preparation of adenyl cyclase from rat kidney. PMID- 4309017 TI - Vascular compression of the optic nerves relieved by anastomosis of carotid artery to jugular vein. PMID- 4309018 TI - Treatment of myasthenia gravis with adrenocorticotropic hormone (ACTH): massive short-term and maintenance treatment. PMID- 4309019 TI - Vincristine neuropathy: an electrophysiological and histological study. PMID- 4309020 TI - Addison's disease and diffuse cerebral sclerosis. PMID- 4309021 TI - Penicillin-induced interictal discharges from the cat hippocampus. I. Characteristics and topographical features. PMID- 4309022 TI - Penicillin-induced interictal discharges from the cat hippocampus. II. Mechanisms underlying origin and restriction. PMID- 4309023 TI - Neuronal behavior and triggering mechanism in cortical epileptic focus. PMID- 4309024 TI - Gross potential from facial nucleus of cat as an index of neural activity in response to glabella tap. PMID- 4309025 TI - Changes in evoked responses from facial nucleus of cat with conditioning and extinction of an eye blink. PMID- 4309026 TI - Comparison of effects of stimulation of Deiters' nucleus and medial longitudinal fasciculus on neck, forelimb, and hindlimb motoneurons. PMID- 4309027 TI - Changes in correlation between monosynaptic reflexes produced by conditioning afferent volleys. PMID- 4309028 TI - [ACTH-producing cells of the anterior pituitary gland]. PMID- 4309029 TI - [Central nervous control of the pituitary-adrenal system, with special reference to the function of the hippocampus in stress]. PMID- 4309030 TI - [CRF (corticotropin-releasing factor)]. PMID- 4309031 TI - [Factors regulating biosynthesis of ACTH]. PMID- 4309032 TI - [Feedback mechanism of ACTH secretion]. PMID- 4309033 TI - [Feedback mechanism of ACTH secretion]. PMID- 4309034 TI - [Inactivation of ACTH]. PMID- 4309035 TI - [In vivo inactivation of ACTH]. PMID- 4309036 TI - [On serum ACTH]. PMID- 4309037 TI - [Action mechanism of ACTH]. PMID- 4309038 TI - [Observation on the action mechanism of ACTH]. PMID- 4309039 TI - [Effect of ACTH (synthetic) and 3',5'-AMP on cholesterol transformation in the adrenocortical mitochondria of cattle]. PMID- 4309040 TI - [Extra-adrenal action of ACTH]. PMID- 4309041 TI - [Extra-adrenal action of ACTH, with special reference to its effect on carbohydrate and lipid metabolism]. PMID- 4309042 TI - [Biochemical pathology of tumor-bearing animals. 1. Glucose]. PMID- 4309043 TI - Epigastric pain, thrombophlebitis, and neurologic deficit. PMID- 4309044 TI - [Clinico-pathological observations on familial amyloid neuropathy, with special reference to 2 autopsy cases in 1 family]. PMID- 4309045 TI - [Autopsy case of extrahepatic cholangioma accompanied by probable leukemoid reaction]. PMID- 4309046 TI - Viral hepatitis and the Australia-SH antigen. PMID- 4309048 TI - Surgical treatment of the foot and ankle in rheumatoid arthritis. PMID- 4309047 TI - Ectopic production of an alkaline phosphatase isoenzyme in patients with cancer. PMID- 4309049 TI - Free radicals produced in a rigid solution of typtophan by a biphotonic process. PMID- 4309050 TI - Photochemistry of tobacco mosaic virus RNA. Effect of HCN. PMID- 4309051 TI - Electron spin resonance studies of the triplet states of monoanionic thymine. PMID- 4309052 TI - [Assessment of the functional state of the adrenal cortex in liver diseases]. PMID- 4309053 TI - [The effect of hydrocortisone on the rat liver nicotinamide-adenine dinucleotide]. PMID- 4309054 TI - [Assessment of the stages of obtaining hormones and of their purity using immunological methods. Detection of thyrotropin derivative]. PMID- 4309055 TI - The stimulatory effect of cyclic adenosine 3'5'-monophosphate on DNA-directed synthesis of beta-galactosidase in a cell-free system. AB - A cell-free system allowing for synthesis of beta-galactosidase enzymatic activity has been developed. This system requires DNA containing the beta galactosidase gene, a cell-free extract of Escherichia coli bacteria, and the low molecular-weight components necessary for transcription of the DNA and translation of the resulting messenger RNA. Such a system is useful for studying enzyme synthesis, as well as its regulation. The gene for beta-galactosidase is part of the lac operon whose expression is under the control of the lac repressor. In whole cells the lac repressor inhibits almost all of the gene expression for beta-galactosidase. In the cell-free system, we had previously been able to repress about half the gene expression. Adding cyclic adenosine 3'5' monophosphate to the cell-free system improved the yield of beta-galactosidase enzymatic activity by 8 to 30 times and the efficiency of repression from 50 to 95 per cent. PMID- 4309056 TI - Biradical spin labeling for nerve membranes. AB - We have explored the behavior of pair interaction in a suitable biradical when it is bound by van der Waals' forces in a nerve membrane. We have concomitantly examined a set of model solvents to represent this situation. It appears that the biradical suffers a restriction of internal motion with a minimal restraint on its external motion in the nerve medium. The biradical is so situated as not to respond to the passage of the action potential. PMID- 4309057 TI - Immunochemistry of the capsular polysaccharide of an acinetobacter. AB - The capsular polysaccharide of a strain, BD4, of Acinetobacter calco-aceticus (A.c-a), composed of L-rhamnose and D-glucose, 4:1, precipitates all streptococcal group B antisera tested, as well as streptococcal group G antisera and antipneumococcal (Pn) type XXIII serum. Nonreducing end groups of L-rhamnose, known to be major determinants of the antigens giving rise to these antisera, are thus identified in A.c-a, which also precipitates anti-Pn VI sera. Both the rhamnose and glucose in the capsular polysaccharide (S) of Pn VI are linked 1,3-, as is the rhamnose in Pn S II, which also precipitates anti-Pn VI because of this linkage. A.c-a and S II precipitate the same fraction of anti-Pn VI, identifying a second portion of the rhamnose of A.c-a as 1,3-linked. This is confirmed by the stability of a portion of the rhamnose on oxidation of A.c-a with periodate, and 1,3-linked glucose or a periodate-stable branch point is also indicated in the same way. Two features of the fine structure of A.c-a have thus been established and a third indicated. PMID- 4309058 TI - [Case of insulinoma with multiple stomach ulcer in an aged woman]. PMID- 4309059 TI - [Function of the mucosal cells of the small intestine after gastrectomy. 2]. PMID- 4309060 TI - [Interesting case of heterotopic ACTH syndrome caused by cancer of the large intestine]. PMID- 4309061 TI - [Study on the etiological factors in neonatal jaundice and chemotherapy]. PMID- 4309062 TI - Electron microscopic localization of enzymes in Mycobacterium tuberculosis. PMID- 4309063 TI - Cyclic guanosine monophosphate: effects on short-circuit current and water permeability. AB - In the isolated toad bladder, cyclic guanosine monophosphate induces an increase in short-circuit current similar to that produced by cyclic adenosine monophosphate. In contrast, cyclic guanosine monophosphate has no effect on water permeability in this organ. This finding raises the possibility that different and independent intra-cellular secondary messengers may exist. PMID- 4309064 TI - Extraparticulate chain interaction between different electron transport particles. AB - Interaction or cross-linking between the respiratory chains of the electron transport particles of bacterial origin occurs with a mixture of active and inactive particles. Interaction between bacterial particles and liver sub mitochondrial particles also occurs. Irradiation of the bacterial particles at 360 nanometers resulted in the destruction of quinone and consequent loss of ability of reduced nicotinamide adenine, dinucleotides to reduce cytochromes b, c(1), c, and a plus a(3). A mixture of both irradiated and untreated particles in the presence of the reduced dinucleotide resulted in the reduction of cytochromes c and a plus a(3), in an amount equivalent to the total concentration of these cytochromes in both types of particles. In contrast, the amount of cytochrome b reduced was equivalent to half the particle concentration or to that observed with the active particles alone. The rate of reduction of cytochromes c and a plus a(3) with the mixture of particles was similar to that with the active particles alone. The interaction or cross-linking between the particulate respiratory chains of bacteria or of bacterial and mammalian systems occurs after cytochrome b and before or at cytochrome c. PMID- 4309065 TI - Experimental herpes encephalitis: crystalline arrays in endoplasmic reticulum. PMID- 4309066 TI - [Veterinary polymyxin and its use in diseases of the young of animals]. PMID- 4309068 TI - Characteristics of two new avian tumor virus subgroups. PMID- 4309067 TI - A comparative study of the DNA density and behavior in tissue cultures of fourteen different herpesviruses. PMID- 4309069 TI - [Morphologic and histochemical changes in the bodies of guinea pigs caused by the C-lecithinase of Cl. welchii type A. 3. Pathomorphologic and histochemical changes in the immune organism]. PMID- 4309070 TI - [Obtaining dry, diagnostic Cl. perfringens type E antiserum]. PMID- 4309071 TI - [Various criteria for demonstrating the relationships between bacteria and viruses. I. Bacteria of the Escherichia coli group as adsorbents of enteroviruses]. PMID- 4309072 TI - [The association of staphylococci with respiratory viruses in acute pneumonia]. PMID- 4309073 TI - [The study of the accommodation ratio in denervated muscles with reference to other electrodiagnoses]. PMID- 4309074 TI - [Neurosurgical considerations and chemotherapeutic aspects]. PMID- 4309075 TI - Tumors of salivary glands. PMID- 4309076 TI - [Physico-chemical, biological and serologic properties of 2 enteroviruses isolated from cattle]. PMID- 4309077 TI - [Influence of the suspension media on the stability of the aftosa virus at different temperatures]. PMID- 4309078 TI - [The importance of initial chemotherapy in tuberculosis control programs]. PMID- 4309079 TI - [Isolation of a cellular strain from a tumor of chemical origin in hamsters]. PMID- 4309080 TI - Search for viral etiology of human leukemia and lymphomas: past efforts and future perspectives. PMID- 4309081 TI - [Round table discussion on mycotoxins]. PMID- 4309082 TI - [Effects of chlorpromazine and hydrocortisone on changes in the enzyme pattern induced by ischemia in rat liver]. PMID- 4309083 TI - [An epidemic episode of poliomyelitis in the City of Taranto. Virological and serological data]. PMID- 4309084 TI - Assay of the antibiotic activity of serum. AB - One of the drawbacks of the "tube dilution" method for the assay of antibiotics in human serum has been illustrated by utilizing serum-sensitive and serum resistant strains of Escherichia coli. In the case of serum-sensitive strains, it was found that fresh serum alone may account for the same degree of inhibition and thus yield minimal inhibitory concentrations identical to those obtained with serum combined with antibiotics, that is, "simulated" serum assay specimens. This fallacy of the method is discussed with regard to those instances in which laboratories were merely to utilize the patient's own coliform organism as the test organism, or with respect to the assay of, for example, polymyxins, in which inadvertently a R(ough) and therefore, serum-sensitive strain of E. coli were to be used as the indicator organism. It is recommended that serum-resistant laboratory strains of Staphylococcus aureus or E. coli of known antibiotic susceptibility be employed as the test organisms proper in order to circumvent the inherent bactericidal activity of serum. PMID- 4309085 TI - [Primary liver cancer in children (apropos of 2 Senegalese cases)]. PMID- 4309086 TI - Quantitative thin-layer chromatographic determination of hippuric acid in rat urine. PMID- 4309087 TI - [Advances and problems in the determination of the renin activity of the blood]. PMID- 4309088 TI - [Advances and problems in angiotensin measurement]. PMID- 4309089 TI - [Hyperosmolar diabetic coma: physiopathologic considerations and therapy]. PMID- 4309090 TI - [Experimental studies on the problem of the hepatoprotective effect of tolbutamide]. PMID- 4309091 TI - The roles of synthesis and degradation in the regulation of catalase levels in the neoplastic tissues. PMID- 4309093 TI - [Study of the enzymatic activities of liver and epididymal adipose tissue of Wistar H rats during a hyperlipidic diet. II. Reversibility when placed on the control diet]. PMID- 4309094 TI - Rhinoviruses and parainfluenza viruses of horses. PMID- 4309092 TI - [Study of the enzymatic activity of liver and epididymal adipose tissue of Wistar H rats during longterm administration of a hyperlipidic diet. I. Development of activities with time]. PMID- 4309095 TI - Comments on rhinoviruses and parainfluenza viruses of horses. PMID- 4309096 TI - Report of the panel for the symposium on immunity to selected equine infectious diseases. Summary. PMID- 4309099 TI - [Compartmentalization of enzymic activities in the spermatozoa of certain gastropod mollusca. I. Localization of dehydrogenases]. PMID- 4309098 TI - Identification of adenosine-3',5'-monophosphate as the bacterial attractant for myxamoebae of Dictyostelium discoideum. AB - Adenosine-3',5'-cyclic monophosphate was shown to be the compound found in Escherichia coli responsible for the attraction of the amoebae of the cellular slime mold Dictyostelium discoideum. A number of other nucleotides were tested and the following were active: tubercidin-3',5'-cyclic monophosphate, N(6)-2'-O dibutyryl-adenosine-3',5'-cyclic monophosphate, 5'-methylene adenosine-3',5' cyclic monophosphonate, guanosine-3',5'-cyclic monophosphate, uridine-3',5' cyclic monophosphate, cytidine-3',5'-cyclic monophosphate, inosine-3',5'-cyclic monophosphate, and thymidine-3',5'-cyclic monophosphate. They were less active than adenosine-3',5'-cyclic monophosphate. It is suggested that cyclic adenosine monophosphate secreted by the bacteria is used by the amoebae as a means of sensing and orienting towards food. PMID- 4309097 TI - Inhibition of protease production of various bacteria by ammonium salts: its effect on toxin production and virulence. AB - Production of protease by many bacteria was found to be inhibited by ammonium salts, and the enzyme production was more sensitive to the salts than was growth of the organisms. Inhibition of protease production by some pathogenic bacteria may result in the recognition of an exotoxin which otherwise would have been digested by the protease. In the case of Pseudomonas aeruginosa, qualitatively different toxicities could be demonstrated in the culture fluids, depending on the presence or absence of protease in such a fluid. The toxicity of the culture in the presence of a high titer of protease may be due primarily to the protease, whereas the toxicity exhibited in the absence of protease could be due to proteinacious exotoxin. Producers of high titers of protease tended to be less virulent in vivo than producers of low titers of the enzyme, which exert their toxicities by a separate exotoxin. PMID- 4309100 TI - Comparison of lipid effects on K+-Mg2+ activated p-nitrophenyl phosphatase and Na+-K+-Mg2+ activated adenosine triphosphatase of membrane. PMID- 4309101 TI - Metabolism of the phosphoinositides in guinea-pig brain synaptosomes. PMID- 4309102 TI - Early events in herpes simplex virus infection: a radioautographic study. AB - The early events in herpes simplex virus infection were studied by means of radio autography. The virus was rapidly taken up by the host cells and uncoated. Viral deoxyribonucleic acid (DNA) reached the nuclear sites of replication in 15 to 30 min after infection. The viral DNA occasionally associated with chromosomes or condensed chromatin but was more frequently found to be randomly distributed. Viral progeny appeared 3 hr after infection. These particles did not show any particular spatial relationship to the parental DNA. The morphological latent period lasted 2.5 hr. PMID- 4309103 TI - 25-hydroxycholecalciferol, the active form of vitamin D--Wisconsin scores again. PMID- 4309104 TI - Central nervous system infections of viral etiology: the changing pattern. PMID- 4309106 TI - Specificity of natural human agglutinins against red cells modified by trypsin and other agents. PMID- 4309105 TI - [Experimental immuno-pathological studies on silicosis. IV. Influence of hypersensitivity reactions towards exogenous and endogenous antigens on silicogenic fibrosis]. PMID- 4309107 TI - [Results of the treatment with hyperbaric oxygen of carbon monoxide poisoning. Apropos of 43 cases]. PMID- 4309108 TI - [Waldenstrom's macroglobulinemia]. PMID- 4309109 TI - The isolation of foot-and-mouth disease virus from African buffalo (Syncerus caffer). PMID- 4309110 TI - Renal artery stenosis and hypertension. Observations on current status of therapy from a study of 115 patients. PMID- 4309111 TI - Further observations on hypoglycaemia in hepatocellular carcinoma. PMID- 4309112 TI - Heat stroke in the aged. PMID- 4309113 TI - [Tarsian canal syndrome. Apropos of 2 further cases]. PMID- 4309114 TI - [Influence of riboflavin deficiency on the activity of acid phosphatase in maternal and fetal organs of rats]. PMID- 4309115 TI - Dynamic asymmetries in the corticosteroid feedback path and distribution metabolism-binding elements of the adrenocortical system. PMID- 4309116 TI - Parameters of the stimulus initiating the adrenocortical response to hemorrhage. PMID- 4309118 TI - Some aspects of visual information input and transmission. PMID- 4309117 TI - Dynamic testing and modeling of adrenocortical secretory function. PMID- 4309119 TI - Interferon and cyclic-3'5'-adenosine monophosphate: potentiation of antiviral activity. PMID- 4309120 TI - Zonal centrifugation of microsomes from rat liver: resolution of rough- and smooth-surfaced membranes. PMID- 4309123 TI - Conformative response of xanthosine 5'-phosphate aminase. PMID- 4309122 TI - Phosphatidate biosynthesis in mitochondrial subfractions of rat liver. AB - 1. After conventional fractionation of rat liver homogenates in 0.88m-sucrose the mitochondrial fraction was subjected to short-term water lysis followed by separation of the resulting membrane preparations. 2. Phosphatidate formation was measured in all subcellular fractions and subfractions and was compared with the distribution of succinate dehydrogenase, monoamine oxidase, rotenone-insensitive NADH cytochrome c reductase, arylsulphatase, urate oxidase, arylesterase and glucose 6-phosphatase. 3. The results obtained indicated that mitochondria were capable of synthesizing phosphatidate, though this activity was only about one third of the total homogenate activity. 4. Mitochondrial phosphatidate formation was located predominantly in the outer mitochondrial membrane. Although this membrane preparation was found to be significantly contaminated by the microsomal fraction, this contamination was estimated to account for not more than about 20% of the total phosphatidate formation observed in preparations of outer mitochondrial membrane. PMID- 4309124 TI - Metabolic control and structure of glycolytic enzymes. IV. Nicotinamide-adenine dinucleotide dependent in vitro reversal of dissociation and possible in vivo control of yeast glyceraldehyde 3-phosphate dehydrogenase synthesis. PMID- 4309121 TI - Studies in vivo on the biosynthesis of collagen and elastin in ascorbic acid deficient guinea pigs. AB - 1. After the administration of labelled proline to guinea pigs deprived of ascorbic acid for 15 days, the dorsal skin was examined 5 days later in an attempt to detect the presence of hydroxyproline-deficient collagen (protocollagen). The extent of incorporation of proline into skin collagens indicated a severe impairment of collagen synthesis. 2. A comparison of proline and hydroxyproline specific radioactivities in diffusible peptides obtained by treatment with collagenase of either purified skin collagens or direct hot trichloroacetic acid extracts of skin failed to indicate the presence of protocollagen. Possible reasons for this are discussed. 3. The incorporation results did not indicate an inability of normal collagen, i.e. collagen hydroxylated to the normal degree, to cross-link in scurvy. 4. Incorporation of labelled proline into aortic elastin isolated from the same animals did not indicate a decrease in elastin biosynthesis in ascorbic acid deficiency, beyond that attributable to the inanition accompanying the vitamin deficiency. The proline/hydroxyproline specific-radioactivity ratio in elastin from scorbutic guinea pigs was about 6:1 in contrast with the 1:1 ratio in control groups. It is concluded that the formation of elastin hydroxyproline was ascorbate-dependent and that a hydroxyproline-deficient elastin is formed and retained in scurvy. The formation of desmosines was unimpaired in scorbutic animals. 5. Studies with chick embryos confirmed the formation of elastin hydroxyproline from free proline. Incorporation of free hydroxyproline into elastin hydroxyproline was negligible. 6. Digestion of solubilized samples with collagenase indicated that the hydroxyproline in guinea-pig aortic elastin preparations was not derived from contamination by collagen. It is suggested that most if not all of the hydroxyproline in the guinea pig elastin preparations investigated can be considered an integral part of the elastin molecule. PMID- 4309125 TI - Metabolic control and structure of glycolytic enzymes. VII. Destabilization and inactivation of yeast glyceraldehyde 3-phosphate dehydrogenase by adenosine phosphates and chymotrypsin. PMID- 4309126 TI - Visible absorption and electron spin resonance spectra of the isolated chains of human hemoglobin. Discussion of chain-mediated heme-heme interaction. PMID- 4309127 TI - 2-keto-4-hydroxybutyrate. Synthesis, chemical properties, and as a substrate for lactate dehydrogenase of rabbit muscle. PMID- 4309128 TI - Studies on adrenal cortical cytochrome P-450. II. Effects of inhibitors of 11 beta hydroxylation on its optical and magnetic properties. PMID- 4309129 TI - Microbial sulfolipids. 3. The disulfate of (+)-1,14-docosanediol in Ochromonas danica. PMID- 4309130 TI - Effects of inorganic pyrophosphate on Neurospora crassa phenylalanine transfer ribonucleic acid ligase in heterologous aminoacylation reactions. PMID- 4309131 TI - On the nature of transfer ribonucleic acid isolated from polyphenylalanyl transfer ribonucleic acid. PMID- 4309132 TI - Poly-5-methyldeoxycyctidylic acid and some alkylamino analogs. PMID- 4309133 TI - Preparation of the 2,4-dinitrophenyl esters of thymidine 3'-and thymidine 5' phosphate and their use as substrates fof phosphodiesterases. PMID- 4309134 TI - Partial purification and preliminary characterization of estrogen-binding globulins from human plasma. PMID- 4309135 TI - Steric effects in the glyceraldehyde 3-phosphate dehydrogenase catalyzed hydrolysis of acyl phosphates. An example of substrate-induced cooperativity. PMID- 4309136 TI - [Interactions between diethylaminoethyl-dextran and deoxyribonucleic acid]. PMID- 4309137 TI - Activity of serum ribonuclease after partial hepatectomy and acute stress in the rat. PMID- 4309139 TI - A simplified procedure for the assay of 5'-nucleotidase. PMID- 4309138 TI - Rapidly labeled cytoplasmic RNA in normal and phytohaemagglutinin-stimulated human lymphocytes. PMID- 4309140 TI - Cytochromes P-450 and b5 in human liver microsomes. PMID- 4309141 TI - Specific transfer of hydrogen from estradiol to progesterone as a regulating principle for progesterone metabolism in the liver of the female rat. PMID- 4309142 TI - Natural occurrence of a new pyridine nucleotide consisting of nicotinamide adenine dinucleotide and adenosine diphosphate ribose joined through a ribosidic link. PMID- 4309143 TI - Preparation and physicochemical properties of human erythrocuprein. PMID- 4309144 TI - Studies on cytochrome c peroxidase. XIV. Recombination of apoenzyme with protoheme dialkyl esters and etioheme. PMID- 4309145 TI - Studies on cytochrome c peroxidase. XV. Comparison of manganese porphyrin containing cytochrome c peroxidase, horseradish peroxidase, and myoglobin. PMID- 4309146 TI - The two-step formation and inactivation of acylphosphatase by agents acting on glyceraldehyde phosphate dehydrogenase. PMID- 4309147 TI - Ligand-induced resistance of staphylococcal nuclease and nuclease-T to proteolysis by subtilisin, alpha-chymotrypsin, and thermolysin. PMID- 4309148 TI - The chromium, manganese, and cobalt complexes of transferrin. PMID- 4309149 TI - The mechanism of 6-deoxyhexose synthesis. 3. Purification of deosythymidine diphosphate-glucose oxidoreductase. PMID- 4309150 TI - The identification of cis-11,12-methylene-2-hydroxyoctadecanoic acid from Thiobacillus thiooxidans. PMID- 4309151 TI - Adenine phosphoribosyltransferase from monkey liver. Specificity and properties. PMID- 4309152 TI - Isolation of diphosphopyridine nucleotide-dependent L-fucose dehydrogenase from pork liver. PMID- 4309153 TI - Rajagopalan KV, Handler P: Purification and properties of inosinic acid dehydrogenase from Escherichia coli. PMID- 4309154 TI - Enthalpy of hydrolysis of the 3' bond of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate. PMID- 4309155 TI - Estrogenic antagonism of metabolic effects of administered growth hormone. PMID- 4309156 TI - Radioimmunoassayable ACTH in dexamethasone nonsuppressible Cushing's syndrome. PMID- 4309157 TI - Observations on cultured cells infected with rinderpest virus by means of fluorescent antibody technique. PMID- 4309159 TI - Decreased 17-hydroxycorticosteroid and VMA excretion during sleep following glutethimide administration in man. PMID- 4309158 TI - ACTH sensitive adenyl cyclase in bovine adrenal cortex membrane fractions. PMID- 4309160 TI - [Changes of E. histolytica from culture under the influence of emetine and fumagillin]. PMID- 4309161 TI - [Extracellular phosphomonoesterase of Bacillus amylozyma]. PMID- 4309162 TI - [Actual tuberculosis therapy. An attempt to simplify and to determine a schedule of tuberculosis chemotherapy]. PMID- 4309163 TI - [Some rare forms of cerebral attacks in children]. PMID- 4309164 TI - [Systemic manifestations of rheumatoid arthritis]. PMID- 4309165 TI - [On the cytologic intravital diagnosis of cytomegalic inclusion disease in children]. PMID- 4309167 TI - [Frey's syndrome]. PMID- 4309166 TI - Sleep and dream studies: current state of the art. PMID- 4309168 TI - [Mucus producing carcinoma of the kidney]. PMID- 4309169 TI - [Endocrine syndromes associated with pancreatic islet cell tumors]. PMID- 4309170 TI - [Suitability of a buffered gelatin-saccharose medium for freeze drying of Bordetella pertussis in comparison with other protective media]. PMID- 4309171 TI - [Development and testing of a combined vaccine against parainfluenza 3, mucosal disease and Pasteurella haemolytica infection in cattle]. PMID- 4309172 TI - The transfer function of frog myoneural junctions. I. The influences of fatigue, facilitation, and depression upon impulse transmission in vitro. PMID- 4309173 TI - Influence of thiazinamium on subcellular p-nitrophenylphosphatase in rat cerebral cortex. PMID- 4309174 TI - [Complex ester grouping in the molecules of ristomycin A and B]. PMID- 4309175 TI - [Effect of kanamycin and florimycin on intracellular located Mycobacterium tuberuclosis and some regularities of interaction of these antibiotics with body cells]. PMID- 4309176 TI - Equilibrium kinetic study of the mechanism of mitochondrial and supernatant malate dehydrogenases of bovine heart. PMID- 4309177 TI - Regulation of the biosynthesis of purine nucleotides in Schizosaccharomyces pombe. II. Kinetic studies of IMP dehydrogenase. PMID- 4309178 TI - Rabbit intestinal glucose-6-phosphate phosphohydrolase and inorganic pyrophosphate-glucose phosphotransferase: inhibition by phlorizin. PMID- 4309179 TI - Cyclic phosphodiesterase having 3'-nucleotidase activity from Bacillus subtilis. Purification and some properties of the enzyme. PMID- 4309180 TI - L-Alpha,gamma-diaminobutyrate-activating enzyme from Bacillus polymyxa. Properties and distribution. PMID- 4309181 TI - The role of essential-SH groups of yeast alcohol dehydrogenase. PMID- 4309182 TI - Stereospecific aging of phosphonylated cholinesterases. PMID- 4309183 TI - Transmural electrical stimulation of the ureter. PMID- 4309184 TI - [CELO virus in gosslings]. PMID- 4309185 TI - Resistance of rabbits and guinea pigs to the diabetogenic effect of streptozotocin. PMID- 4309186 TI - Early insulin synergistic activity of growth hormone. PMID- 4309187 TI - Characteristics of family caretakers. PMID- 4309189 TI - Reactivity of plasmalogens: kinetics of acid-catalyzed hydrolysis. AB - The acid-catalyzed hydrolysis of the alpha,-unsaturated ether group of two plasmalogens, lysophosphatidal choline and lysophosphatidal ethanolamine, and several model compounds (isobutyl vinyl ether, 1-butenyl ethyl ether, and dihydropyran) was studied by determining the true second-order rate constants. The results indicate that the chemical reactivity of the substituted vinyl ether group in plasmalogens is not appreciably affected by the presence of a bulky substituent on the -carbon. Activation energies, enthalpies, and entropies were also determined (from measurements of the rate constants at different temperatures). PMID- 4309188 TI - Isolation and identification of phospholipids of bovine rhodopsin. AB - Phospholipids present in digitonin solutions of bovine rhodopsin have been identified and assayed. Digitonin interferes with extraction of lipids by the usual methods; digitonin was therefore removed from the preparation as an ergosterol digitonide, soluble in absolute ethanol but precipitated in 80% ethanol. The supernatant 80% ethanol contained one portion of the phospholipid, mainly choline and ethanolamine phosphoglycerides with traces of serine phosphoglyceride and sphingomyelin. The rhodopsin residue (free from digitonin) was extracted with chloroform-methanol 2:1; this extract contained the rest of the phospholipid, which consisted only of choline and ethanolamine phosphoglycerides. Plasmalogens were not found, but could have decomposed during the procedures. PMID- 4309190 TI - Synthesis of lipids from acetate by human preputial and abdominal skin in vitro. AB - Lipogenesis in vitro from acetate-1-(14)C was studied in human preputial skin and abdominal skin. Radioactive lipids were separated by column chromatography on Florisil and by thin-layer chromatography on silica gel. Radioactivity was incorporated chiefly into the triglyceride, sterol, and polar lipid fractions, while lesser amounts of (14)C were found in the hydrocarbon, wax, diglyceride, monoglyceride, and fatty acid fractions; labeling of steryl esters was minimal. On thin-layer chromatography, the radioactive polar lipids had mobilities similar to lysolecithin, phosphatidyl choline, phosphatidyl ethanolamine, and phosphatidic acid. The radioactive fatty acids of the different lipid fractions were separated by gas-liquid chromatography. The major (14)C-labeled acids were 16:0 and 18:0. Radioactivity was also detected in acids 14:0, 15:0, 16:1, 18:1, 18:2, 20:0, 20:1, 22:0, 24:0, 24:1, and 26:0. No radioactivity could be detected in arachidonic acid, although this fatty acid comprises 9% of the chromatographed fatty acids. The pattern of incorporated (14)C was different from the percentage mass composition of the fatty acids. Skin is therefore active in the biosynthesis of a wider variety of lipids than previously demonstrated. PMID- 4309191 TI - Tissue distribution of glycosphingolipids in a case of Fabry's disease. AB - A survey was made of the glycolipid composition of various tissues, including liver, spleen, kidney (cortex and medulla), lymph node, pancreas, prostate gland, heart muscle, thenar muscle, gastrointestinal smooth muscle, frontal cerebral cortex, anterior thalamus, brain stem, a peripheral autonomic ganglion, and renal arterial intima and media, from a patient who died with Fabry's disease. The tissues had been fixed in formalin for 3 yr. Analytical data on trihexosyl ceramide from heart muscle and pancreas indicate a structure identical to trihexosyl ceramide from kidney: galactosylgalactosylglucosyl ceramide. Fatty acid compositions of trihexosyl ceramide and dihexosyl ceramide revealed a wide range of fatty acids, with 16:0, 18:0, 20:0, 22:0, 24:0, and 24:1 predominating. These glycolipids comprised 10-41% of the total lipid in the formalin-fixed organs studied. Trihexosyl ceramide predominated in all tissues and was the only glycolipid found in muscle tissues, lymph node, and arterial tissues. Dihexosyl ceramide was found in kidney, pancreas, liver, spleen, and cerebral tissues. The accumulation of trihexosyl ceramide in cardiac muscle and arterial tissues may account in part for the cardiovascular complications so prominent in Fabry's disease. PMID- 4309193 TI - Determination of individual conjugated bile acids in human bile. AB - A method has been developed and validated for the determination of the six major conjugated bile acids, cholesterol, and total phospholipids in bile of human subjects previously injected with 4-(14)C-cholesterol. The procedure is designed for use with 5-10 ml of duodenal or T-tube bile and eliminates difficulties associated with existing methods for bile acid determination, in particular the requirement for preliminary saponification under pressure or the use of paper chromatography. Saponification under pressure is employed only in steps where partial destruction of the steroid moiety of conjugated bile acids is not a crucial matter. A preliminary Folch extraction and washing step separated free cholesterol and phospholipids (bottom layer) from the six major conjugated bile acids (top layer). The conjugated bile acids were then fractionated cleanly by thin-layer chromatography to give four groups, the (14)C content of each of which was determined. A second aliquot of the top layer was used to determine (after deconjugation) the radioactivity ratio of deoxycholic acid to chenodeoxycholic acid for the two unresolved groups (dihydroxycholanoic acid conjugates with glycine and taurine, respectively). A third aliquot was used for determination of specific activities of the methyl esters of cholic, chenodeoxycholic, and deoxycholic acids derived from the total bile salts. Appropriate calculations yielded the concentration in bile of all six major bile acid conjugates. PMID- 4309192 TI - Identification of ceramide phosphorylethanolamine and ceramide phosphorylglycerol in the lipids of an anaerobic bacterium. AB - Nearly half the phospholipids isolated from the anerobic bacterium Bacteroides melaninogenicus are phosphosphingolipids. The two major phosphosphingolipids have been characterized as ceramide phosphorylethanolamine and ceramide phosphorylglycerol. The long-chain bases of these phosphosphingolipids appear to have branched and normal saturated carbon chains of 17, 18, and 19 atoms; the phosphate is at the 1-position of the long-chain base. The composition of the amide-linked fatty acids of the phosphosphingolipids differs from that of the ester-linked fatty acids of the diacylphosphoglycerides in having a higher percentage of 14:0, 17:0, and 18:0 acids as well as containing nearly all the monoenoic fatty acids found in the bacterial lipids. The finding of phosphosphingolipids in bacteria is exceedingly rare and to our knowledge ceramide phosphorylglycerol has not been previously found in nature. PMID- 4309194 TI - Composition of alkoxylipids of human heart and aorta. AB - The major alkoxylipids of human heart and aorta are alkyl and alk-1-enyl diacyl glycerols, alkyl acyl and alk-1-enyl acyl glycerophosphoryl cholines, and the corresponding glycerophosphoryl ethanolamines. There are no pronounced differences in the composition of corresponding classes of alkoxylipids from heart, aorta, and other human tissues previously reported. PMID- 4309195 TI - Minor footnote to Michigan Medical History: the Lansing strain of poliomyelitis virus. PMID- 4309196 TI - [Therapeutic trial of multiple sclerosis using immunosuppressive agents]. PMID- 4309197 TI - [Adenovirus infections and ornithosis among military recruits]. PMID- 4309198 TI - Review of virus respiratory infections in the Milwaukee area, 1955-65. PMID- 4309199 TI - The presence of the adult-type pattern of adrenal steroids in the one day old rat. PMID- 4309200 TI - Conjugation of androsterone by the guinea-pig kidney in vitro. AB - Radioactive androsterone was incubated with kidney slices from guinea pigs in a Ringer bicarbonate buffer. For analysis, the radioactivity was partitioned between chloroform and water for the separation of non-polar and polar steroids. After multiple chromatography procedures, the non-polar fraction was shown to contain androsterone and at least four other similar steroids, not identified in this study. The polar fraction yielded numerous conjugates from which androsterone glucuronide and androsterone sulphate in approximately equal quantities were isolated and characterized. PMID- 4309202 TI - Phosphoenolpyruvate carboxytransphosphorylase. V. Mechanism of the reaction and the role of metal ions. PMID- 4309201 TI - Phosphoenolpyruvate carboxytransphosphorylase. 3. Comparison of the fixation of carbon dioxide and the conversion of phosphenolpyruvate and phosphate into pyruvate and pyrophosphate. PMID- 4309204 TI - Sequential degradation of nucleic acids. Degradation of Escherichia coli B phenylalanine transfer ribonucleic acid. PMID- 4309203 TI - Spin-label studies of glycerinated muscle fibers. PMID- 4309205 TI - Pentose synthesis in Escherichia coli. PMID- 4309206 TI - The oxidation of thioethers by bromine. A model system for oxidative phosphorylation. PMID- 4309207 TI - The role of G factor in protein synthesis. Studies on a temperature-sensitive Escherichia coli mutant with an altered G factor. PMID- 4309208 TI - The pathways of corticosteroid biosynthesis by homogenates of adrenal tissue from rabbits stimulated with adrenocorticotropin. PMID- 4309209 TI - Chemical synthesis of three deoxyribododecanucleotide chains of defined sequence. PMID- 4309210 TI - Ligand interactions with hemoprotein P-450. II. Influence of phenobarbital and methylcholanthrene induction processes on P-450 spectra. PMID- 4309211 TI - The biosynthesis of bacteriochlorophyll. The characterization of latter stage intermediates from mutants of Rhodopseudomonas spheroides. PMID- 4309212 TI - The conformation of angiotensin II in aqueous solution. II. Dialysis and gel filtration behavior of [Asn 1-Val 5]-angiotensin II. PMID- 4309213 TI - [Action of heparin on human erythrocytic angiotensinase in vitro]. PMID- 4309214 TI - Postoperative gas gangrene. PMID- 4309215 TI - Postoperative clostridial infections in Britain. AB - Eighty-five cases of clostridial infection, including 56 cases of gas gangrene, followed "clean" surgical operations performed in British hospitals in the course of two years. Nearly all the serious infections followed amputations of the leg for ischaemia or other operations on the leg in which a foreign body was implanted. All the infections were sporadic, and the evidence suggested that the infecting organism usually came from the bowel of the patient. Nearly half of the operations were performed in modern theatres with satisfactory ventilation and unexceptionable arrangements for the sterilization of instruments and dressings.Skin sterilization was often carried out perfunctorily or with agents with poor sporicidal activity. Total eradication of spores from the skin is, however, difficult to achieve, and recontamination may occur during the operation. Hence it is considered justifiable to give penicillin prophylactically to the small group of patients at serious risk from postoperative gas gangrene. PMID- 4309216 TI - [Research on the regulation of carbohydrate metabolism in vivo. I. Action of ethionine]. PMID- 4309218 TI - [Electrophoretic separation on polyacrylamide gels of mono, bi, and pluricatenary forms of poliovirus ribonucleic acid]. PMID- 4309217 TI - [Study of the formation of n-butanol in Clostridium acetobutylicum]. PMID- 4309219 TI - [Morphological changes in the lungs after experimental intrabronchial administration of oily contrast media]. PMID- 4309220 TI - On the mechanism of the enzymatic conversn of cholest-5-ene-3-beta, 7-alpha-diol into 7-alpha-hydroxycholest-4-en-3-one. PMID- 4309221 TI - [Spatial summation within the receptive field center of lateral geniculate body neurons in the cat]. PMID- 4309223 TI - Drugs and dreams, a synthesis. PMID- 4309222 TI - Electron histochemical observation of succinic dehydrogenase activity in various parts of neurons. PMID- 4309225 TI - Some considerations of motor and electrical acitivity in states of diminished awareness. PMID- 4309224 TI - ACTH-excess and increased urinary pressor activity. PMID- 4309226 TI - Susceptibility of various strains of chicken to the oncogenicity of Yaba virus. PMID- 4309227 TI - [On the incidence of cytomegalic virus infections]. PMID- 4309228 TI - [Experimental hypertension, especially on spontaneously hypertensive rats]. PMID- 4309229 TI - Preparation of radioactively labeled monodisperse silica spheres of colloidal size. PMID- 4309231 TI - The hierarchy of resort in curative practices: the Admiralty Islands, Melanesia. PMID- 4309230 TI - Traditional healers and their female clients: an aspect of Nigerian sickness behavior. PMID- 4309232 TI - Urban illness: physicians, curers and dual use in Bogota. PMID- 4309233 TI - Effect of nitrofurazone on the aerobic metabolism of uniformly labelled [14C]glucose in tissue slices of rat testes. PMID- 4309234 TI - Tinel's percussion test. PMID- 4309235 TI - [Fungal 5'-phosphodiesterases and their properties]. PMID- 4309236 TI - Specific inhibition of an antibody response by affinity labelling. PMID- 4309237 TI - In vivo studies of the FBJ murine osteosarcoma virus. PMID- 4309238 TI - Treatment of Cushing's disease. Correction of hypercortisolism by o,p'DDD without induction of aldosterone deficiency. PMID- 4309239 TI - Catecholamine-secreting paraganglioma of glomus-jugulare region resembling pheochromocytoma. PMID- 4309240 TI - Hereditary deafness in man. PMID- 4309241 TI - Persistence of foot-and-mouth disease virus in lymph nodes and blood of experimentally infected buffalo-calves in West Pakistan. PMID- 4309242 TI - Respiratory infection of lambs with an ovine strain parainfluenza virus type 3. PMID- 4309243 TI - [Some considerations on the treatment of eczema in infants and eczema in early childhood with cortisone and ACTH]. PMID- 4309244 TI - Hormonal pattern in bronchial asthma (reversible obstructive lung disease). 1. Role of adrenal steroids. PMID- 4309245 TI - Effect on the lungs and their regional lymph nodes of BCG and quartz dust. An experimental study on rats. PMID- 4309246 TI - Effect of BCG on translocation of quartz dust from the lungs to their regional lymph nodes. An experimental study on rats. PMID- 4309247 TI - The problem of the chronic excretor of tubercle bacilli. PMID- 4309248 TI - Visceral and behavioral responses to intraduodenal fat. AB - Introduction of milk or corn oil into the duodenum of the cat evokes an increase in superior mesenteric blood flow (blocked by atropine), an inhibition of gastric and duodenal motility, and sedation. Cholecystokinin-pancreozymin mimics the mesenteric vascular effect of intraduodenal fat and seems to have a sedating action. PMID- 4309249 TI - Energy flux and membrane synthesis in photosynthetic bacteria. AB - Synthesis of the energy-converting membrane complex of the photosynthetic purple bacterium Rhodopseudomonas capsulata during growth under different conditions of energy flux was studied by examining the disorganizing effects of polymyxin B, with or without lysozyme, on integrity of the cell envelope. Cells growing with a limited supply of energy show an elevated bacteriochlorophyll content and increased resistance to breakdown of the "permeability barrier" by these agents. It seems that purple bacteria respond to energy restriction by preferentially synthesizing excess bacteriochlorophyll-membrane which, in effect, toughens the cell integument. PMID- 4309250 TI - Clinical epidemiology of leukemia. PMID- 4309252 TI - Natural occurrence and experimental study of pox and Haemoproteus infections in a mute swan (Cygnus olor). PMID- 4309251 TI - Exposure of vaccinated bulls and steers to airborne infection with foot-and mouth disease. PMID- 4309253 TI - Scintillation counting of 14CO2 from in vitro systems: a comparison of some trapping agents. PMID- 4309254 TI - Liquid scintillation radioassay of thin-layer chromatograms: problems in the use of external standard quench correction. PMID- 4309255 TI - [Cycasin-induced renal tumors in the Wistar rat with special consideration of the adenoma]. PMID- 4309256 TI - Porphyrins derived from the prosthetic group of myeloperoxidase. PMID- 4309257 TI - The mechanism of cycloheximide inhibition of protein synthesis in rabbit reticulocytes. PMID- 4309258 TI - The regulation of glycolate metabolism in Chlamydomonas reinhardtii. PMID- 4309261 TI - Rapid resolution of flavin-adenine dinucleotide and its mononucleotides on cellulose layers using aqueous ammonium salts and formic acid. PMID- 4309260 TI - Phenoxy radical intermediates in the enzymatic degradation of lignin model compounds. PMID- 4309259 TI - Cell wall composition and protoplast formation of some Oomycete species. PMID- 4309263 TI - [Effect of L-malate on oxidation of citrate and D-isocitrate in mitochondria of potato tubercles]. PMID- 4309262 TI - Brain monoamines and adrenocortical activation. AB - 1. The effect of a pharmacologically induced increase or depletion of brain monoamines (5-hydroxytryptamine, noradrenaline, dopamine) was investigated with respect to adrenocortical function.2. No strict correlation was found between the depletion of brain amine stores induced by prenylamine or p-chlorophenylalanine and adrenocortical activation, even at times in which the peak effect of brain amine depletion occurs.3. Restraint stress causes a manifest increase in brain 5 hydroxytryptamine while decreasing the cerebral noradrenaline and dopamine content. This stress strongly stimulates corticosterone secretion by the adrenals.4. A monoamine oxidase inhibitor, nialamide, at a dose which causes an evident increase in brain amine concentrations, does not modify plasma corticosterone. At the same dose it was, furthermore, unable to prevent the adrenocortical stimulation induced by restraint stress.5. Brain amine content does not seem to play an important part in the control of corticotrophin releasing factor in corticotrophin secretion by the pituitary gland. The relationship between hypothalamic monoamines and other neurohumours is discussed. PMID- 4309264 TI - [Adaptation of a cytomegalic virus from fieldmice (Apodemus sylvaticus) on various heterologous cells, human included]. PMID- 4309265 TI - [Intercellular reactions. Demonstration of an inhibitor of protein synthesis diffusing in cells incubated at high concentration]. PMID- 4309267 TI - [Synergism and antagonism of some substances with angiotensin]. PMID- 4309266 TI - [The cycle of the mammary adenocarcinoma virus in mice and its relations to milk secretion]. PMID- 4309268 TI - [Demonstration of a polyoma virus strain not inducing a transplantation protection antigen]. PMID- 4309269 TI - [Phosphoglucomutase and glucose-6-phosphatase activities of the retina and anthocyanoside extracts from Vaccinium myrtillum (study in vitro and vivo)]. PMID- 4309270 TI - [Effect of destruction of neurons containing catecholamines of the mesencephalon on the wake-sleep cycle in cats]. PMID- 4309271 TI - [Biologic activities of phospholipids of the so-called atypical and scotochromogenic P6 Mycobacterium strain]. PMID- 4309272 TI - [Cytologic modifications of the pituitary and interrenal gland of the green frog, Rana esculenta L., after unilaternal adrenalectomy]. PMID- 4309273 TI - [Respiratory manifestations in drepanocytosis]. PMID- 4309274 TI - The mechanism of plateau formation by anemone toxin. PMID- 4309276 TI - [ACTH or glucocorticoid treatment?]. PMID- 4309275 TI - [Report of experience with homologous liver transplantation]. PMID- 4309277 TI - Lithium and the electroencephalogram during sleep. PMID- 4309278 TI - Adjuvant properties of alginate in bacterial, viral and protein vaccines. PMID- 4309280 TI - [The soft palate and multiple cancer]. PMID- 4309279 TI - Evaluation of metopiron and ACTH tests in prolonged corticosteroid treatment of chronic asthma. PMID- 4309281 TI - The genesis of dermatoglyphics. PMID- 4309282 TI - Fifty-two forms of childhood cancer: United States mortality experience, 1960 1966. PMID- 4309283 TI - [Coincidence of 4 primary malignant tumors. Tracheal resection and direct anastomosis in the treatment of tracheal tumors]. PMID- 4309284 TI - [Cytomegalia in children with acute leukemia and neoplasms]. PMID- 4309285 TI - [Diurnal urine excretion of catecholamines and DOPA in tumors of the sympathetic nervous system in children]. PMID- 4309286 TI - [Primary tumor of the heart in combination with cytomegalia in a 5-year-old child]. PMID- 4309287 TI - [Autoimmune thyroiditis (pathogenesis, clinical picture, diagnosis and treatment)]. PMID- 4309288 TI - [Treatment of some endocrine diseases by administration of radioactive yttrium into hypophysis]. PMID- 4309289 TI - [Secretion of corticosteroids by adrenal glands of guinea pigs after hypophysectomy]. PMID- 4309290 TI - [Nature of the insular apparatus of the pancreas in chronic stress]. PMID- 4309291 TI - Biological effects of ultrasound: non-toxicity to poliovirus. PMID- 4309292 TI - Studies on the relation of melatonin to sleep. PMID- 4309293 TI - Some guanidine esters and their possible relationship to the action of tetrodotoxin. PMID- 4309294 TI - Thermoregulation in the rat: interactions of cholinergic and adrenergic agents in the hypothalamus. PMID- 4309295 TI - The pharmacology of 2-imino-5-benzoyloxy-hexahydropyrimidine. PMID- 4309296 TI - Effect of EDTA and other chelating agents on norepinephrine uptake by rabbit aorta in vitro. PMID- 4309297 TI - Pharmacological and biochemical correlates of 5-hydroxytryptamine entry into the central nervous system during maturation. PMID- 4309298 TI - NAD effects on the biochemistry and psychological performance of alcoholics under ethanol stress. PMID- 4309299 TI - [Development of poliomyelitis virus in Staphylococcus aureus cells]. PMID- 4309300 TI - Sarcoma of the stomach: a review of 39 cases. PMID- 4309301 TI - Effect of maternal antibody on Marek's disease. PMID- 4309302 TI - Buffalopox virus. PMID- 4309305 TI - [On a method of explantation of the human tonsil]. PMID- 4309303 TI - [On the nature of the diseases of peripheral nervous system]. PMID- 4309304 TI - [Electron microscopic study of an extra-mammary Paget's disease]. PMID- 4309306 TI - The active chemical state of D-glyceraldehyde 3-phosphate in its reactions with D glyceraldehyde 3-phosphate dehydrogenase, aldolase and triose phosphate isomerase. AB - Glyceraldehyde 3-phosphate exists as the geminal diol and the free aldehyde in the molar ratio 29:1 in aqueous solution. The rate constant of the conversion of diol into aldehyde is 8.7x10(-2)sec.(-1) in the pH range 7.3-8.6 at 20 degrees . The free aldehyde is the substrate for d-glyceraldehyde 3-phosphate dehydrogenase. Over a wide concentration range of enzyme the rate of conversion of diol into aldehyde is the rate-limiting process in the catalytic oxidation of d-glyceraldehyde 3-phosphate by NAD(+). Aldolase and triose phosphate isomerase both liberate d-glyceraldehyde 3-phosphate as the aldehyde. This suggests that the relatively slow diol-aldehyde interconversion does not restrict the rate of glycolysis. PMID- 4309307 TI - Purification of a trifunctional enzyme, catalysing three steps of the histidine pathway, from Neurospora crassa. AB - 1. A procedure is described for the purification of an enzyme from Neurospora crassa that has three catalytic functions. These are 1-N-(5'-phosphoribosyl)-ATP pyrophosphohydrolase, 1-N-(5'-phosphoribosyl)-AMP cyclohydrolase and histidinol dehydrogenase (l-histidinol-NAD oxidoreductase, EC 1.1.1.23), and are responsible for the catalysis of reactions 2, 3 and 10 in the histidine pathway. The ratio of these three catalytic activities remains approximately the same throughout the purification procedure. Evidence is presented that the purified preparations contain a single protein exhibiting association-dissociation equilibria. PMID- 4309308 TI - Amino acid uptake in isolated chick embryo heart cells. AB - 1. The preparation of cell suspensions by treatment of chick embryo hearts with collagenase at various stages of development is described. 2. Measurements of oxygen consumption, incorporation of labelled leucine into protein and accumulation of labelled alpha-aminoisobutyric acid against a concentration gradient indicated a long-lasting viability of the isolated heart cells in vitro; a satisfactory preservation of subcellular structures, including plasma membrane, was assessed by electron-microscopic examination. 3. The rate of alpha aminoisobutyric acid accumulation by cardiac cells isolated from hearts at different stages of embryological development decreased with aging; insulin stimulated the intracellular accumulation of this amino acid analogue. 4. Insulin increased the uptake by isolated heart cells of several (14)C-labelled naturally occurring amino acids; however, the fraction of amino acid taken up by the cells that was recovered free intracellularly, and therefore the concentration ratio (between intracellular water and medium), was enhanced by the hormone only with glycine, proline, serine, threonine, histidine and methionine. When isolated heart cells were incubated in the presence of a mixture of labelled amino acids, the addition of insulin increased the disappearance of radioactivity from the medium. 5. The general pattern of amino acid transport (in the absence and in the presence of insulin) in isolated cardiac cells was similar to that found in intact hearts, suggesting that the biological preparation described in this paper might be useful for studies of cell permeability and insulin action. PMID- 4309309 TI - Isomers of glucosaminylphospatiylglycerol in Bacillus megaterium. AB - 1. The lipids of Bacillus megaterium were extracted and three lipids containing glucosamine were identified. One of these is not a phospholipid, but the other two, which differ in their chromatographic behaviour, contain phosphorus, glycerol, fatty acid and d-glucosamine in the molar proportions 1:2:2:1. 2. In both phosphoglycolipids, the fatty acids are bound in ester linkage, and both yield 2,5-anhydromannose and 3-sn-phosphatidyl-1'-sn-glycerol on treatment with sodium nitrite. 3. Both phosphoglycolipids were N-acetylated and, after removal of fatty acids by mild alkaline hydrolysis, in both cases N-acetylglucosamine was quantitatively released by beta-N-acetylhexosaminidase. 4. The glucosaminylglycerols derived from the two phosphoglycolipids by partial acid hydrolysis differ in their behaviour towards periodate. In one case 1 mole of periodate is rapidly consumed/mole of glucosaminylglycerol, but in the other case under identical conditions the consumption of periodate is negligible. 5. The phosphoglycolipids were identified as 1'-(1,2-diacyl-sn-glycero-3-phosphoryl)-3' O-beta-(2-amino-2-deoxy-d-glucopyranosyl)-sn-glycerol and as 1'-(1,2-diacyl-sn glycero-3-phosphoryl)-2'-O-beta-(2-amino-2-deoxy-d-glucopyranosyl)-sn-glycerol. 6. Both phosphoglycolipids are good substrates for phospholipase A: neither is a substrate for phospholipase C from Clostridium perfringens, and only the 3' glucosaminide is a substrate for phospholipase D. PMID- 4309310 TI - Presence, induction and possible role of glucose 6-phosphatase in mammalian pancreatic islets. AB - 1. Pancreatic islets from several mammalian species were investigated for hydrolytic activity towards glucose 6-phosphate. Both the total phosphatase activity towards this substrate and the proportion cleaving glucose 6-phosphate in preference to beta-glycerophosphate varied widely between species. In pancreatic-islet homogenates prepared from mice and guinea pigs there was a higher rate of liberation of P(i) at pH6.7 from glucose 6-phosphate than from beta-glycerophosphate. In these two species cortisone treatment enhanced the enzyme activity towards glucose 6-phosphate but not that towards beta glycerophosphate. Simultaneous injections of ethionine or puromycin blocked this stimulating effect of cortisone. 2. With whole homogenates of mouse pancreatic islets, inverse plots of the relationship between glucose 6-phosphate concentration and enzyme activity suggested the simultaneous action of two enzymes with different K(m) values. After fractionation of islets from obese hyperglycaemic mice by differential centrifugation, one of these enzymes could be shown to be localized in the microsome fraction. It had K(m) for glucose 6 phosphate about 0.5mm and optimum pH6.7. It split glucose 6-phosphate in preference to beta-glycerophosphate, glucose 1-phosphate, fructose 6-phosphate and fructose 1,6-diphosphate. Incubation of the microsomes at pH5.0 and 37 degrees for 15min. decreased the enzyme activity by about 80%. Glucose was a potent inhibitor, the type of inhibition being neither strictly competitive nor non-competitive. It is suggested that the results indicate the presence of glucose 6-phosphatase in mammalian endocrine pancreas, and that this enzyme may play a role in the metabolic regulation of release of insulin. PMID- 4309313 TI - A survey of sheep sera for antibodies to an ovine strain of parainfluenza 3 virus. PMID- 4309312 TI - The isolation of a basic coupling factor from preparations of factor F3. PMID- 4309311 TI - 1-Anilinonaphthalene-8-sulphonate, a fluorescent conformational probe for glutamate dehydrogenase. AB - 1. The interaction of 1-anilinonaphthalene-8-sulphonate with ox liver glutamate dehydrogenase was examined. 2. The fluorescence of the dye is enhanced 100-fold on binding. 3. A further enhancement is observed when NADH and GTP are added to the enzyme. 4. By using this property of the dye to measure conformational equilibria in the enzyme the effects of coenzyme, inhibitors, enzyme concentration, ionic strength and pH on the allosteric transitions were studied. 5. GTP and NADH interact with the enzyme in a heterotropic manner. 6. The rate of the structural transition brought about by GTP and NADH is biphasic with half lives of 34 and 200msec. 7. The relation of these observations to regulatory mechanisms is discussed. PMID- 4309315 TI - [Necessity of pure precursors to express a transformation character in BHK 21-13 cells]. PMID- 4309316 TI - [Clinical and angiographic findings in islet cell adenoma]. PMID- 4309314 TI - Serological findings in bovine herpes mammillitis. PMID- 4309317 TI - Tetrazolium salt reduction studies in slide histochemistry. I. Observations on the reductase activity of experimental tumours implanted in the mouse brain and liver, as measured by optical densitometry. PMID- 4309318 TI - Tetrazolum salt reduction studies in slide histochemistry. II. A quantitative study in two experimental tumour models. PMID- 4309320 TI - Detection and separation of aliphatic polycarboxylic acids by reversed-phase partition thin-layer chromatography. PMID- 4309319 TI - [Development and chemical differentiation of the rat kidney with special reference to sex differences]. PMID- 4309321 TI - [The effect of Menrium on the vaginal cell picture in female castrates and the influencing of so-called climacteric disorders]. PMID- 4309322 TI - [The effect of ACTH on the steroidogenesis in the adrenal glands of rat embryos in experiments in vitro]. PMID- 4309323 TI - [The effect of ACTH on cholesterol metabolism and blood proteins]. PMID- 4309324 TI - [One of the possible mechanisms of the blood ACTH content rise in traumatic shock]. PMID- 4309325 TI - [Tuberculosis endemic disease on the Ivory Coast and clinical aspects of tuberculosis in Africa]. PMID- 4309327 TI - [Physiotherapy of posttraumatic peripheral paralyses]. PMID- 4309326 TI - [Findings on the success of vaccination and revaccination with live and inactivated vaccines against poliomyelitis]. PMID- 4309328 TI - [Casts in after care of injuries of peripheral nerves]. PMID- 4309329 TI - Pelvic arteography in malignant trophoblastic neoplasia. PMID- 4309331 TI - [Quantitative separation of estrogens from oil solutions by thin layer chromatography and their gas chromatographic and colorimetric determination]. PMID- 4309330 TI - [Separation and determination of testosterone esters in oil solutions]. PMID- 4309332 TI - [Synthesis of nucleic acids in cells derived from HS6 tumor and infected by herpetic virus]. PMID- 4309333 TI - [Latent infection in laboratory mice. Isolation of reovirus type 3]. PMID- 4309334 TI - [n the morphologic characters of normal, virus infected or tumor inducing mouse cells in primary or line culture]. PMID- 4309335 TI - 5-Phosphoribosyl pyrophosphate synthetase from Ehrlich ascites tumor cells. PMID- 4309336 TI - Transfer areas and clean zones in operating suites. PMID- 4309338 TI - Contribution on the etiology of acute stenosing laryngotracheobronchitin in children. PMID- 4309337 TI - The isolation of parainfluenza 4 subtypes A and B in England and serological studies of their prevalence. PMID- 4309339 TI - Measurement of reticuloendothelial system phagocytosis and catabolism: a new method. PMID- 4309340 TI - Lysosomal enzyme release in mouse strains susceptible and resistant to antigen antibody complex induced anaphylactic shock. PMID- 4309341 TI - Effects of cholera on the human hypothalamus and hypophysis. II. PMID- 4309342 TI - [Bang's disease and the peripheral nervous system]. PMID- 4309343 TI - Bacteriophage sigma factor for RNA polymerase. PMID- 4309344 TI - Interactions of proteins and lipids: structure and polymorphism of protein-lipid water phases. PMID- 4309345 TI - Does strychnine block inhibition post-synaptically? PMID- 4309346 TI - Encoding of nerve signals from retinal rods. PMID- 4309347 TI - Metabolic and morphologic studies of hepatocarcinogenesis in the rat. ANL-7535. PMID- 4309348 TI - Survival of mice under daily gamma irradiation: progress report for incidence of some tumors. ANL-7535. PMID- 4309350 TI - Effect of rapid eye movement (dreaming) sleep deprivation on retention of avoidance learning in rats. Rep No 563. PMID- 4309353 TI - Histochemical studies of alkaline phosphatase in carcinoma of the liver. PMID- 4309351 TI - Phosphohydrolase activity of a Bacillus species. PMID- 4309355 TI - Congenital cytomegalovirus infection. PMID- 4309354 TI - Calcified carcinoma of the colon superimposed on chronic ulcerative colitis. PMID- 4309356 TI - Glutaraldehyde-treated cells in the indirect hemagglutination tests for amebiasis. PMID- 4309357 TI - Indirect hemagglutination and ameba-immobilization tests and their evaluation in intestinal and extraintestinal amebiasis. PMID- 4309352 TI - Experimental study on atherosclerosis--an attempt at its prevention and treatment. PMID- 4309358 TI - Hydrolytic enzymes in the neonatal rat lung. PMID- 4309359 TI - Enzyme suppression by Mycobacterium bovis. PMID- 4309360 TI - Studies on the location of sulfhydryl groups in erythrocyte membranes with magnetic resonance spin probes. PMID- 4309361 TI - Sarcoplasmic reticulum. 8. Use of 8-anilino-1-naphthalene sulfonate as conformational probe on biological membranes. PMID- 4309362 TI - ESR probing of macromolecules: function and operation of structural units within the active site of alpha-chymotrypsin. PMID- 4309363 TI - Reversed energy conversion reactions of bacterial photophosphorylation. PMID- 4309364 TI - Altered properties of thymidine kinase induced in hamster kidney cells by adenovirus types 5 and 12. PMID- 4309365 TI - Effect of substrates on reconstitution of the mitochondrial respiratory chain under various conditions. PMID- 4309366 TI - A nitrite reductase with cytochrome oxidase activity from Micrococcus denitrificans. PMID- 4309367 TI - Purification and properties of cytochromes c of Azotobacter vinelandii. PMID- 4309368 TI - Electron spin resonance studies of free radicals derived from plastoquinone, alpha- and gamma-tocopherol and their relation to free radicals observed in photosynthetic materials. PMID- 4309369 TI - [2 cases of intracranial adenoid cystic carcinoma]. PMID- 4309370 TI - [Medulloblastoma and pituicytoma]. PMID- 4309371 TI - [Infundibulo-pituicytoma and granular-cell myoblastoma--clinical study]. PMID- 4309373 TI - [Influence of fasting on golden hamster anterior pituitary cells. Electron microscope study]. PMID- 4309372 TI - [Case of muscular dystrophy associated ith coincidental lower motor neuron lesion]. PMID- 4309374 TI - [Effects of disulfram on sleep states in cats]. PMID- 4309375 TI - [New data on the influence of ultraviolet irradiation of Polyoma virus on the transplantation antigen]. PMID- 4309377 TI - [Effect of sodium salicylate and of ACTH on the regeneration of the corneal epithelium under experimental conditions]. PMID- 4309376 TI - The isolation of estrone sulfate and estradiol-17 beta sulfate from stallion testes. PMID- 4309378 TI - Virus particles in epidermodysplasia verruciformis with carcinoma. PMID- 4309379 TI - The effect of luteinizing hormone and adenosine 3',5'-monophosphate on progesterone biosynthesis by bovine granulosa cells in culture. PMID- 4309380 TI - Transformation of cells cultured from human brain tissue. PMID- 4309381 TI - Studies on polymer of adenosine diphosphate ribose. VI. Radioautographic demonstration of incorporation of NAD into nuclear macromolecule. PMID- 4309382 TI - [Study of the chemotherapeutic effect of sanguinarine]. PMID- 4309383 TI - [Experimental studies on the effect of low oxygen inhalation on adrenocortical secretion--by the retention cannula method for collecting lumbo-adrenal venous blood in the dog]. PMID- 4309384 TI - [The determination of alpha-ketoglutaric acid in bacterial cultures]. PMID- 4309385 TI - Transplantation of spontaneous hepatomas in C3H mice; biological and biochemical studies. PMID- 4309386 TI - Modes of action of three bacteriostatic agents in their inhibitory effect on induction of hepatoma in rats fed 4-(dimethylamono)-azobenzene. I. Effect on metabolic fate of 4-(dimethylamino)azobenzene. PMID- 4309387 TI - Immunological studies on in vivo liver catalase-depressing substance. PMID- 4309388 TI - Interference of leukemogenesis by mammary tumorigenesis in a colony of AKR mice. PMID- 4309389 TI - In vitro culture of human cancer cells for cancer chemotherapy. II. In vitro drug sensitivity of cultured suspended cell line of gastric carcinoma origin. PMID- 4309391 TI - Diagnosis and management of mediastinal masses in children. PMID- 4309390 TI - Effect of histological fixation on carbohydrate-rich tissue compounds and their periodate consumption. PMID- 4309392 TI - Acid angiotensinase as a lysosomal enzyme. PMID- 4309394 TI - Centrally mediated vasopressor effect of angiotensin II in man. PMID- 4309393 TI - Responses of the cardiac sympathetic receptors to various substances. PMID- 4309395 TI - Heat resistance and alpha-toxigenicity of Clostridium perfringens strains in normal intestines of Japanese. PMID- 4309396 TI - Ibaraki virus, an agent of epizootic disease of cattle resembling bluetongue. I. Epidemiologic, clinical and pathologic observations and experimental transmission to calves. PMID- 4309397 TI - Ibaraki virus, an agent of epizootic disease of cattle resembling bluetongue. II. Isolation of the virus in bovine cell culture. PMID- 4309398 TI - Incorporation of 32P into phospholipids of influenza A and parainfluenza 1 viruses. PMID- 4309399 TI - [Acute pancreatitis in a 11-year-old boy as complication from viral common cold]. PMID- 4309400 TI - Hydrocephalus in hamsters, ferrets, rats, and mice following inoculations with reovirus type I. I. Virologic studies. PMID- 4309401 TI - Hydrocephalus in hamsters, ferrets, rats, and mice following inoculations with reovirus type I. II. Pathologic studies. PMID- 4309402 TI - The fine structure of brown adipose tissue. 3. The effect of cold exposure and its mediation in newborn rats. PMID- 4309403 TI - Clinical observations on cancer patterns at the non-white hospital Baragwanath, Johannesburg, 1948-1964. PMID- 4309404 TI - Atypical peripheral (bronchiolar) adenoma of the lung. PMID- 4309406 TI - [Lines of transplantable OKB cells]. PMID- 4309407 TI - [Isolation of cytomegalovirus from children with various forms of malignant neoplasms]. PMID- 4309408 TI - [On the roentgenodiagnosis of synovial sarcomas]. PMID- 4309405 TI - Improved method for measurement of renin activity in human plasma. PMID- 4309409 TI - [The clinical picture and treatment of synovial sarcomas of the extremities]. PMID- 4309411 TI - Alterations of some proteosynthetic reactions in the course of immunisation with heterologous proteins. PMID- 4309410 TI - The neurologist's view of radiation therapy of nervous tissue. PMID- 4309412 TI - The virus watch program: a continuing surveillance of viral infections in metropolitan New York families. 8. PMID- 4309414 TI - [Apropos of a case of incontinentia pigmenti]. PMID- 4309415 TI - [Summary of ten years of studies on the subject of the nervous system of the skin]. PMID- 4309413 TI - Ecologic studies of vesicular stomatitis virus. I. Prevalence of infection among animals and humans living in an area of endemic VSV activity. PMID- 4309416 TI - [Research on carbon-quartz interactions in development of pneumoconioses of miners]. PMID- 4309417 TI - [Our experience with surgical treatment of syndactylias of the hand]. PMID- 4309418 TI - Positional distribution of fatty acids in brain polyphosphoinositides. PMID- 4309420 TI - [Neurologic diseases caused by enteroviruses in children]. PMID- 4309421 TI - [Tumors of the endocrine pancreatic tissue]. PMID- 4309419 TI - Treatment of adenovirus infection of the eye with 5-iodo-2'-deoxyuridine. A double-blind trial. PMID- 4309422 TI - [Mediastinal neoplasms, Report on 22 surgical cases]. PMID- 4309423 TI - [Disease due to cytomegalic inclusion]. PMID- 4309424 TI - [Cl. perfringens type A as the causative agent of acute gastrointestinal diseases in young children]. PMID- 4309425 TI - [On the effect of the addition of copper-containing compounds to quartz dust on the development of experimental silicosis in rats]. PMID- 4309426 TI - [On the problem of the accumulation of lipids in lung macrophages in experimental silicosis]. PMID- 4309427 TI - [Liver resection in tumors of the child]. PMID- 4309429 TI - [Are brain metastases curable?]. PMID- 4309428 TI - Dextrochrysin, a new antibiotic. PMID- 4309430 TI - [Treatment of inflammatory conditions of the external auditory passage with a combination of polymyxin B, neomycin and fluocinolone acetonide]. PMID- 4309431 TI - [Histolopic and enzymatic study of contusive lesions of the encephalon]. PMID- 4309432 TI - [Calcifications in pituitary adenomas]. PMID- 4309433 TI - Relief of uremic polyneuropathy after bilateral nephrectomy. PMID- 4309435 TI - [On the phagocytic activity of migrating macrophages in skin windows in patients with viral hepatitis]. PMID- 4309434 TI - [Tumoral pulmonary embolism]. PMID- 4309436 TI - [On further knowledge of chlorophylls and hemins. XXIX. The reversible alteration of optical and magnetic properties of titanium-octaethylporphine through protonation]. PMID- 4309437 TI - [Immunization of poultry against pseudoplague]. PMID- 4309438 TI - [Absolute age determination of subfossil bones by the derivatographic method. Preliminary report]. PMID- 4309439 TI - Fate of angiotensin I and II in the human pulmonary circulation. PMID- 4309441 TI - Plain film roentgen diagnosis of amebic hepatic abscess. PMID- 4309440 TI - Treatment of infectious granulomas of the liver and infectious mononucleosis. Treatment of hepatic schistosomiasis, tuberculosis, syphilis and echinococcus cyst. PMID- 4309442 TI - Functional hepatoma demonstrated with rose bengal scanning. PMID- 4309443 TI - Recent advances in pediatric surgery. PMID- 4309444 TI - Some recent advances in endocrine surgery. PMID- 4309445 TI - Clinical advances in the treatment of cancer. PMID- 4309446 TI - Progress in abdominal surgery. PMID- 4309447 TI - Tumors of the salivary glands. PMID- 4309448 TI - [Histochemical study of the genesis of mouse metanephros]. PMID- 4309449 TI - Effect of morphine on cerebral glycolytic intermediates and enzymes of rats in vitro. PMID- 4309450 TI - Comparison of the biochemical alterations elicited in livers from rats treated with carbon tetrachloride, chloroform, 1,1,2-trichloroethane and 1,1,1 trichloroethane. PMID- 4309451 TI - Identification of somatotropin as the hormone in a mixture of somatotropin, adrenocorticotropic hormone and prolactin which decreased liver drug metabolism in the rat. PMID- 4309452 TI - Serological studies in infectious mononucleosis. AB - Serological investigations performed on 27 patients with illnesses resembling infectious mononucleosis showed a significant increase in high antibody titres (more than 1:40) to EB virus in 11 of the 12 who developed heterophile antibodies. Two of these patients, however, had a significant increase in antibody titre to cytomegalovirus and rubella virus, respectively. Of 15 patients who failed to develop heterophile antibodies, one had a high antibody titre to EB virus, the others generally having undetectable or low antibody titres. The insidious onset of the illness in many patients together with the fact that EB virus antibodies rose to high titres rapidly reduced the value of this investigation diagnostically.EB virus antibody was still present in the sera of five patients who had had well-authenticated heterophile-antibody-positive infectious mononucleosis some four to seven years previously. Twenty-seven out of 70 (39%) healthy nurses had antibody at a level of more than 1:10 to EB virus. The presence of EB virus antibody in different population groups appears to be related to such factors as age and socioeconomic status. PMID- 4309453 TI - Weak ankles. A study of common peroneal entrapment neuropathy. AB - Twenty-three patients were seen with entrapment neuropathy in a two-and-a-half year period. Symptoms consisted of pain, paresis, and paraesthesia in the distribution of the common peroneal nerve. Some degree of paresis was often present, which in five patients was severe enough to cause drop foot. In 20 patients decompression of the entrapped nerve at the neck of the fibula was quickly and completely successful. It is suggested that the ankle weakness which frequently follows sprains and other forced inversion injuries may often be at least partially due to entrapment of the common peroneal nerve. PMID- 4309454 TI - A tetrodotoxin-resistant primary afferent depolarization. PMID- 4309455 TI - Sleep of unrestrained chimpanzee: cortical and subcortical recordings. PMID- 4309457 TI - An electroencephalographic study of nocturnal sleep in temporal lobe epilepsy. PMID- 4309456 TI - Pyramidal excitation of lemniscal neurons and facilitation of sensory transmission in the spinal trigeminal nucleus of the cat. PMID- 4309458 TI - Effect of diazonium derivatives on myosin A adenosine triphosphatase. II. A possible conformational change induced by ATP. PMID- 4309459 TI - The isolation of cytopathogenic enteroviruses from the sewage in Moscow and the Moscow district in 1963-1964. 2. The efficacy of purification of sewage from cytopathogenic enteroviruses. PMID- 4309460 TI - Vascular invasion by glioma cells in man: an electron microscopic study. PMID- 4309461 TI - "Ephphatha, or, some advice to stammerers". PMID- 4309463 TI - Immunization of mice against Ehrlich ascites tumour using a hamster-Ehrlich ascites tumour hybrid cell line. PMID- 4309462 TI - Computer-generated plots of results of antimicrobial-susceptibility tests. PMID- 4309464 TI - [Study of the adrenal gland function using a synthetic delayed-action ACTH]. PMID- 4309466 TI - The metabolic and endocrine response to acute medical stress. PMID- 4309467 TI - Treatment of ovarian carcinoma: surgical aspects. PMID- 4309465 TI - Effects of drugs on placental function and their relation to congenital abnormalities. PMID- 4309468 TI - The effect of small doses of human ACTH on serum corticosteroid levels in man. PMID- 4309469 TI - Skin, liver, and corneal lesions produced by injections of high infectious titer and UV-irradiated preparations of herpes simplex virus in rabbits and guinea pigs. PMID- 4309470 TI - The effect of dextrans on zeta potential. PMID- 4309471 TI - Enhanced virus yields and decreased interferon production in mycoplasma-infected hamster cells. PMID- 4309472 TI - Serum immunoglobulins in multiple sclerosis patients. PMID- 4309474 TI - Resistance to virus challenge in mice infected with protozoa or bacteria. PMID- 4309473 TI - The effect of proinsulin on the immunoassay of insulin and its possible relation to states of hyperinsulinemia. PMID- 4309475 TI - Purine analogs as potential anticytomegalovirus agents. PMID- 4309476 TI - Adrenal response to excess corticotropin in coronary-prone men. PMID- 4309477 TI - Adrenal response to hypophysectomy in the newborn dog. PMID- 4309478 TI - The pathology of experimental infectious canine hepatitis in neonatal puppies. PMID- 4309479 TI - Observations on the histopathology of bovine herpes mammillitis. PMID- 4309480 TI - Human diploid cell transformation by DNA extracted from the tumor virus SV40. AB - The DNA isolated from simian virus 40 (SV40) can transform human fibroblast cells in tissue culture. Clonal lines of DNA-transformed human cells have been obtained that have properties characteristic of cells transformed by whole virus. They all contain SV40 T-antigen, and infectious virus can be recovered by cocultivation. This is the first demonstration of a permanent genetic alteration produced in human cells by purified DNA. PMID- 4309481 TI - [Experimental gingivitis]. PMID- 4309482 TI - Nursing care approaches for operant reinforcement with psychiatric patients. PMID- 4309483 TI - Toward a greater understanding of mutual withdrawal in a psychiatric setting. PMID- 4309484 TI - Psychiatric nursing in a unique environment. PMID- 4309485 TI - An adjunct to training psychiatric acids in behavioral modification techniques. PMID- 4309486 TI - Group treatment for handicapped children. PMID- 4309487 TI - Therapy of being-with: reentrance to existence. PMID- 4309488 TI - Health systems in the socialized countries. PMID- 4309489 TI - Psychiatric drugs & trends. The bitter and the sweet of sweeteners. PMID- 4309490 TI - Speaking out on: caring plus standards. PMID- 4309491 TI - Geriatrics (automobile driving). PMID- 4309492 TI - Going home. PMID- 4309493 TI - Studies in situ on the neuroendocrine system of the giant water bug, Belostoma indica (Lep. and Serv.) (Heteroptera: Belostomatidae). PMID- 4309494 TI - Activation of cardiac glycogen phosphorylase by calcium. PMID- 4309496 TI - Morphological description of cell cultures containg a Type-II (Marek's) leukosis virus (JM strain). PMID- 4309495 TI - Influence of prostaglandin E1 on the terminal vascular bed. PMID- 4309497 TI - Bioassay of cell cultures containing a Type-II leukosis virus (JM strain). PMID- 4309498 TI - Chicken embryo lethal orphan virus: virus localization and histopathology in chicken embryos. PMID- 4309499 TI - Studies on acute marek's disease. XI. propagation of the GA isolate of marek's disease in tissue culture. PMID- 4309500 TI - The fibrogenic action of silica. PMID- 4309501 TI - Persistence of the steroidogenic effect of adenosin-3',5'-monophosphate in vitro: evidence for a third factor during the steroidogenic effect of ACTH. PMID- 4309502 TI - Fetal secretion of glucocorticoids. PMID- 4309503 TI - [Electron microscopic cytochemistry of the nucleus and the nucleolus]. PMID- 4309504 TI - Molecular states of cytochrome oxidase. PMID- 4309505 TI - Fine structure of Sendai virus nucleocapsid. PMID- 4309506 TI - Course of air-borne infection cause by B virus (Herpesvirus simiae) II. Distribution of B virus in the organism of rabbits and histopathological changes in the organs. PMID- 4309507 TI - Angiotensin II analogs. I. Synthesis and biological evaluation of [Gly-1,Gly 2,Ile-5]-angiotensin II, [Ac-Gly-1,Gly-2,Ile-5]-angiotensin II, and [Gly-1,Gly 2,Ile-5,His(Bzl)-6]-angiotensin II. PMID- 4309508 TI - Angiotensin II analogs. II. Cyclo-(-Val-Tyr-Ile-His-Pro-Phe-). PMID- 4309509 TI - Serological epidemiology of reovirus infection. 1. PMID- 4309510 TI - Progress at home with a mentally retarded child. PMID- 4309512 TI - The cranial mononeuropathies. PMID- 4309511 TI - Trigeminal sensory neuropathy. PMID- 4309513 TI - Effect of glutethimide and aminoglutethimide on the pituitary-adrenal system. PMID- 4309514 TI - Relief of decerebrate rigidity by viscero-somatic reflex action. PMID- 4309515 TI - Safety in a pharmacology laboratory. PMID- 4309516 TI - Iontophoretic application of acetylcholine to thermoregulatory centers of rats. PMID- 4309518 TI - [Suppression of proliferation of transplantable tumors induced by Friend virus in rats, with special reference to alloplasia of the tumor cells by virus infections]. PMID- 4309517 TI - [Budd-Chiari syndrome, with special reference to secondary Budd-Chiari syndrome]. PMID- 4309519 TI - [Antineoplastic spectrum of vincristine sulfate in transplantable ascite hepatoma in rats]. PMID- 4309520 TI - [Mechanism of ACTH secretion in the pituitary gland]. PMID- 4309521 TI - [Protein-binding corticotropin and hypothalamic corticotropin]. PMID- 4309522 TI - A comparative evaluation of metronidazole and other amoebicidal drugs on the strains of Entamoeba histolytica. PMID- 4309523 TI - Serum electrophoretic patterns in angiography. PMID- 4309524 TI - Modification of insulin response and alloxan diabetes by hypothalamic lesions in rats. PMID- 4309525 TI - Three cases of hepatocellular carcinoma with unusual presentation. PMID- 4309526 TI - Lipolytic activity of ACTH and its fragments on isolated fat cells of the rat: inhibition by different types of antisera. PMID- 4309527 TI - Distribution of enzymes in mesophyll and parenchyma-sheath chloroplasts of maize leaves in relation to the C4-dicarboxylic acid pathway of photosynthesis. AB - 1. Mesophyll and parenchyma-sheath chloroplasts of maize leaves were separated by density fractionation in non-aqueous media. 2. An investigation of the distribution of photosynthetic enzymes indicated that the mesophyll chloroplasts probably contain the entire leaf complement of pyruvate,P(i) dikinase, NADP specific malate dehydrogenase, glycerate kinase and nitrite reductase and most of the adenylate kinase and pyrophosphatase. The fractionation pattern of phosphopyruvate carboxylase suggested that this enzyme may be associated with the bounding membrane of mesophyll chloroplasts. 3. Ribulose diphosphate carboxylase, ribose phosphate isomerase, phosphoribulokinase, fructose diphosphate aldolase, alkaline fructose diphosphatase and NADP-specific ;malic' enzyme appear to be wholly localized in the parenchyma-sheath chloroplasts. Phosphoglycerate kinase and NADP-specific glyceraldehyde phosphate dehydrogenase, on the other hand, are distributed approximately equally between the two types of chloroplast. 4. After exposure of illuminated leaves to (14)CO(2) for 25sec., labelled malate, aspartate and 3-phosphoglycerate had similar fractionation patterns, and a large proportion of each was isolated with mesophyll chloroplasts. Labelled fructose phosphates and ribulose phosphates were mainly isolated in fractions containing parenchyma-sheath chloroplasts, and dihydroxyacetone phosphate had a fractionation pattern intermediate between those of C(4) dicarboxylic acids and sugar phosphates. 6. These results indicate that the mesophyll and parenchyma sheath chloroplasts have a co-operative function in the operation of the C(4) dicarboxylic acid pathway. Possible routes for the transfer of carbon from C(4) dicarboxylic acids to sugars are discussed. PMID- 4309528 TI - The small-scale isolation and characterization of adrenocorticotrophin. AB - Several methods for isolating adrenocorticotrophin from small quantities of porcine and bovine pituitary tissue are compared. Initial extraction of the hormone by an acid-acetone technique was simpler and more efficient than one employing acetic acid extraction and ether precipitation. Subsequent purification procedures utilizing adsorption of the peptide on to oxycellulose realized the highest yields. CM-cellulose-column chromatography followed by Sephadex-gel filtration were suitable final steps for obtaining highly purified adrenocorticotrophin. The purity of the hormone was demonstrated by determining its amino acid composition, C-terminal analysis, polyacrylamide-gel electrophoresis, chymotrypsin digestion and paper electrophoresis and by radioimmunoassay and bioassay. Adrenocorticotrophin was found to be rapidly destroyed in intact and especially in homogenized glands kept at room temperature. At 4 degrees the rate of destruction was less rapid and at -20 degrees losses were minimal. PMID- 4309529 TI - Changes in the concentrations of hepatic metabolites on administration of dihydroxyacetone or glycerol to starved rats and their relationship to the control of ketogenesis. AB - 1. Glycerol and dihydroxyacetone, both antiketogenic and readily metabolized, but differing in their effects on the redox state of the hepatic NAD couples, were given to starved rats and the contents of metabolites were measured in freezeclamped liver and in the blood. The object was to study the effects of changes in the redox state and of the availability of oxidizable substrates on the rate of ketone-body formation. 2. Intramuscular administration of dihydroxyacetone, glycerol or glucose to starved rats decreased the concentrations of acetoacetate and 3-hydroxybutyrate in the blood by 70-80% within 60min., whereas there was no major change in the free fatty acid concentration. 3. Dihydroxyacetone, but not glucose or glycerol, caused an immediate and sustained twofold increase in the blood lactate concentration. 4. Dihydroxyacetone and glycerol caused a rapid fall in the hepatic concentrations of ketone bodies, dihydroxyacetone being more effective. 5. This decrease was not accompanied by significant changes in the concentrations of acetyl-CoA, long chain acyl-CoA or free CoA. 6. The hepatic glycerophosphate concentration rose about 40-fold on administration of glycerol, whereas with dihydroxyacetone the increase was only about 50%. The large increase in glycerophosphate concentration after administration of glycerol was completely prevented by pretreatment of the rats with tri-iodothyronine. Triiodothyronine-treated rats showed the same decrease in ketone-body concentrations after administration of glycerol as the untreated rats. 7. Glycerol and dihydroxyacetone caused an increase in the hepatic lactate concentration; the pyruvate concentration rose only after injection of dihydroxyacetone. 8. Both compounds increased liver glycogen. 9. Calculation of the [free NAD(+)]/[free NADH] ratios indicated that dihydroxyacetone increased the ratio in cytoplasm and mitochondria, whereas glycerol caused a prompt fall in both compartments, followed at 10min. by a slight rise in the mitochondrial compartment. 10. Dihydroxyacetone did not alter the hepatic content of ATP. 11. The findings suggest that the main reason for the antiketogenic effect of glycerol and dihydroxyacetone was a consequence of their ready metabolism and the provision of an increased supply of C(3) intermediates for conversion into oxaloacetate. Under the test conditions, neither the hepatic content of alpha-glycerophosphate nor the redox state of the NAD couples appeared to play a major role in the regulation of ketogenesis. PMID- 4309530 TI - The inhibition of pyruvate and Ls(+)-isocitrate oxidation by succinate oxidation in rat liver mitochondria. AB - 1. The effects of succinate oxidation on pyruvate and also isocitrate oxidation by rat liver mitochondria were studied. 2. Succinate oxidation was without effect on pyruvate and isocitrate oxidation when respiration was maximally activated with ADP. 3. When respiration was partially inhibited by atractylate, succinate oxidation severely inhibited the oxidation of pyruvate and isocitrate. 4. This inhibitory effect of succinate was associated with a two- to three-fold increase in the reduction of mitochondrial NAD(+) but no change in the reduction of cytochrome b. 5. It is concluded that, in the partially energy-controlled state, respiration is more severely inhibited at the first phosphorylating site than at the other two. 6. The effects of succinate oxidation are compared with those of palmitoylcarnitine oxidation. It is concluded that a rapid flow of electrons directly into the respiratory chain at the level of cytochrome b is in itself inadequate to inhibit the oxidation of intramitochondrial NADH. 7. The effects of succinate oxidation on pyruvate oxidation were similar in rat heart and liver mitochondria. PMID- 4309531 TI - Chemical modification of glutamate dehydrogenase by 2,4,6 trinitrobenzenesulphonic acid. AB - 1. Modification with 2,4,6-trinitrobenzenesulphonic acid was studied for its effect on the structure, activity and response to regulatory effectors of ox liver glutamate dehydrogenase. 2. The modification affected amino groups only, and the relative reactivities of the amino groups of the enzyme are described. 3. A biphasic inactivation of the enzyme was observed and analysis of the course of inactivation and of modification showed that the rapid reaction of one amino group/subunit leads to loss of 80% of the enzymic activity. 4. NADH retarded the inactivation by 2,4,6-trinitrobenzenesulphonic acid, the protection increasing with NADH concentration. This, together with the previous observation, suggests that the rapidly reacting group is essential for the activity of the enzyme. 5. The effects of modification on the optical-rotatory-dispersion and sedimentation behaviour of the enzyme were studied. 6. The enzyme's response to the allosteric effector GTP was rapidly lost on modification, whereas its response to ADP was unaffected. Comparison of the inactivation and desensitization suggests that the reactive amino group is essential for both activity and GTP response, and that only a completely unmodified enzyme oligomer responds fully to GTP. 7. The merits of chemical-modification studies of large enzymes are discussed critically in connexion with the interpretation of these results. PMID- 4309532 TI - Stereochemistry of phytoene biosynthesis by isolated chloroplasts. AB - The incorporation of [2-(14)C,(5R)-5-(3)H(1)]MVA* and [2-(14)C,5-(3)H(2)]MVA into geranylgeraniol and phytoene by a preparation of ;non-aqueous' bean leaf chloroplasts has been studied. In the formation of phytoene from two molecules of geranylgeranyl pyrophosphate, the loss of hydrogen is stereospecific, the hydrogen atom lost from C-1 of each molecule of geranylgeranyl pyrophosphate being that which was originally the pro-S hydrogen atom from C-5 of mevalonate. All the pro-R hydrogen atoms from C-5 of mevalonate are retained. These results with a cell-free system confirm and extend the observations made in previous work with tomato slices. PMID- 4309533 TI - Brain hexokinase. The preparation of inner and outer mitochondrial membranes. PMID- 4309534 TI - Myosin modification as studied by spin labeling. PMID- 4309535 TI - Characterization of rat heart myosin. II. Enzymatic properties. PMID- 4309536 TI - The synthesis of guanosine 5'-diphosphate D-rhamnose. PMID- 4309537 TI - Kinetic studies of the mechanism and allosteric activation of the reaction catalyzed by nucleoside diphosphatase. PMID- 4309538 TI - Purification and properties of two vitamin B12 binders from chicken serum. PMID- 4309539 TI - [Preliminary note on use of an inactivated vaccine against equine plague]. PMID- 4309540 TI - [Presence of antibodies in sheep serum inhibiting hemagglutination with myxovirus parainfluenza]. PMID- 4309541 TI - [Virus-like bodies in cells of lymphosarcoma of dog]. PMID- 4309542 TI - [Synergic oncogenic effect of 2-N-fluorenylacetamide and carbon tetrachloride on rat liver]. PMID- 4309543 TI - [Synergic oncogenic action of 4-dimethylaminoazobenzole and carbon tetrachloride on rat liver]. PMID- 4309544 TI - [Myoepithelial clear cell tumor of the parotid gland]. PMID- 4309545 TI - Estimation of 5'-nucleotidase activity in nervous tissue. PMID- 4309546 TI - Some clinical aspects of peripheral nerve lesions. PMID- 4309547 TI - [Histochemical studies of the human myometrium in the course of labor]. PMID- 4309548 TI - [Clinical aspects of renovasular hypertension]. PMID- 4309549 TI - [Therapy of thyrotoxicosis]. PMID- 4309550 TI - Mossbauer studies of bonding in iron porphyrin-ligand systems. PMID- 4309552 TI - Effects of electroanesthesia on synaptic ultrastructure. PMID- 4309551 TI - [Acoustic tomography of intracranial expansive processes. Preliminary results in the adult using an experimental apparatus]. PMID- 4309553 TI - Relationships between the concentration of liver metabolites and ketogenesis in chickens fed "carbohydrate-free" diets. PMID- 4309554 TI - Respiration of isolated liver mitochondria from chickens fed "carbohydrate-free" diets. PMID- 4309555 TI - [Data on the mechanism of angiotensin vascular action produced by the use of alpha and beta adrenergic inhibitors]. PMID- 4309556 TI - [Thermogenesis and post-contractile fluorescence variations of amphibian striated muscle]. PMID- 4309557 TI - [Natriuretic and hydrosmotic responses to theophylline in Rana esculenta after adaptation to low temperature]. PMID- 4309558 TI - [Intestinal absorption and silicon blood transport in ovariectomized rats]. PMID- 4309559 TI - [Effects of weaning as a function of age on the wake-sleep cycle in guinea pigs]. PMID- 4309560 TI - [Multi-unit activity of subcortical structures during waking and sleeping in cats]. PMID- 4309561 TI - [Hippocampus neuronal discharges during waking and sleeping]. PMID- 4309562 TI - [Effect of 8-lysinevasopressin in man on the plasma concentration of corticotropic and somatotropic hormones]. PMID- 4309563 TI - [Study of the peri-ependyma of the cat oval fasciculus]. PMID- 4309564 TI - [Effects of unilateral adrenalectomy on pituitary and adrenal gland cytology in Rana esculenta L]. PMID- 4309565 TI - [Remarks on fetal and maternal glycemias and insulinemias in rats]. PMID- 4309566 TI - [Action of thyroid hormones by the oxido-reduction state of the NAD-NADH system in vivo]. PMID- 4309567 TI - [Centrifugal influences exerted on pigeon retina]. PMID- 4309568 TI - [Neurons containing monoamines in cat brain stem. II. Biochemical and neurophysiologic study]. PMID- 4309569 TI - [Comparative localization of spontaneous rhythmic cortical activities of sleeping and waking in free cats]. PMID- 4309570 TI - [Discussion of the ganglionic action of angiotensin. Importance of doses and techniques to determine physiologic influence]. PMID- 4309571 TI - [Role of barosensitive zones in determining the renal vasomotor reactions set off by a continuous intravenous intake of angiotensin]. PMID- 4309572 TI - [Effect of ouabain and cyclic A.M.P. on the catecholamine output of the isolated adrenal gland]. PMID- 4309573 TI - [Characteristics of spontaneous transitory activation during slow and rapid sleep in man]. PMID- 4309574 TI - [The depth of paradoxal sleep in cats: threshold of reticular stimulation and detection of significant or insignificant sound stimuli]. PMID- 4309575 TI - [Interaction of ouabain and lipolytic drugs]. PMID- 4309576 TI - [Studies of the enterovirus effect on the course of dysentery in children]. PMID- 4309577 TI - [Ulcerous lesions of the intestines in cytomegaly]. PMID- 4309578 TI - Rapid eye movements and rapid eye movement periods. PMID- 4309579 TI - [Localization and dynamics of virus-specific RNA synthesis in Ehrlich ascites carcinoma cells infected with Sendai virus]. PMID- 4309580 TI - [Lysosomal factors of the resistance of transformed cells to reinfection with homologous virus]. PMID- 4309581 TI - [5 years of observing monkeys infected with simian virus 40 during the 1st days of life]. PMID- 4309582 TI - [Concentration and purification of parainfluenza type 3 virus and adenoviruses types 4 and 6 by ammonium sulfate sedimentation]. PMID- 4309583 TI - [A study of the intestina; viral flora of children ill with rheumatism]. PMID- 4309584 TI - [Histochemical investigations of carcinogenesis in rat liver after continuous application of diethylnitrosamine]. PMID- 4309585 TI - [Histochemical investigations of carcinogenesis in rat liver after time-limited application of diethylnitrosamine]. PMID- 4309586 TI - [The effect of phenobarbital and halogenated hydrocarbons on nitrosamine carcinogenesis]. PMID- 4309587 TI - [Angiomatic variations of benign giant cell synovioma]. PMID- 4309588 TI - [Peliosis hepatis. Recent contributions on the role of hormonal factors]. PMID- 4309589 TI - Purification of mouse brain phosphoserine phosphohydrolase and phosphotransferase. PMID- 4309590 TI - Calcium-binding protein and calcium absorption after vitamin D administration. PMID- 4309591 TI - A study on some spectral properties of P-450 in a submicrosomal particle. PMID- 4309592 TI - Studies on oxidative phosphorylation. XIX. Functional site of factor B in energy transfer reactions. PMID- 4309593 TI - Neuropathy induced by hemorrhage. PMID- 4309594 TI - Posterior interosseous nervepalsy in the absence of trauma. PMID- 4309595 TI - The effects of pH and citrate on the activity of nicotinamideA-denine dinucleotide-specific isocitrate dehydrogenase from pea mitochondria. AB - 1. The effect of pH on the co-operative activation of the NAD-specific isocitrate dehydrogenase from pea mitochondria by isocitrate is shown. 2. The interlinked effects of pH on the affinity of the NAD-specific isocitrate dehydrogenase for isocitrate and the dependence of the pH optimum on the substrate concentration are presented. 3. A consideration of the conditions of pH and substrate concentration under which citrate activates the NAD-specific isocitrate dehydrogenase demonstrates similarities between the binding of isocitrate and citrate. 4. A comparison of the effects of citrate and pH on the gross structure of the enzyme is investigated by density-gradient centrifugation. 5. The kinetic interpretations of these results are briefly considered. 6. The metabolic significance of these studies is discussed. PMID- 4309596 TI - The effects of calcium and magnesium ions on the adenosine triphosphatase and inosine triphosphatase activities of myosin A. AB - 1. The effects of Ca(2+) and Mg(2+) on the enzymic activity of myosin were studied with myosin preparations treated by the ion-exchange resin Chelex-100. A reaction mixture containing 0.05m-potassium chloride was chosen in which the effects of univalent ions such as K(+), Na(+) and Cl(-) do not change significantly with small variations in their concentrations. 2. The relationship between the rate of hydrolysis of ATP or ITP and the concentration of Ca(2+) suggests that a relatively weak binding of Ca(2+) either to myosin or to the substrate nucleotide is responsible for the activation of the enzymic activity. According to the experiments with an ultrafiltration technique, the binding of Ca(2+) to myosin proceeds in at least two steps, the first occurring at one site on every 500000 atomic mass units of myosin with an apparent association constant, K(app.), 1.3x10(6)m(-1), and the second seeming to be so weak that its binding parameters cannot be determined by the method used. The first type of Ca(2+) binding is not observable with N-ethylmaleimide-modified myosin, yet this modified myosin shows activation by Ca(2+) of its adenosine triphosphatase and inosine triphosphatase. 3. The inhibition by Mg(2+) can be related to a binding reaction of Mg(2+) with myosin having K(app.) approximately 10(6)m(-1). Mg(2+) replaces the Ca(2+) bound tightly to myosin. The K(app.) for Mg(2+)-myosin binding calculated by assuming a competition between Ca(2+) and Mg(2+) for the same site is 2.1x10(5)-3.0x10(5)m(-1). When myosin is modified with a thiol reagent (p-mercuribenzoate) at a certain ratio to myosin, the inhibition by Mg(2+) becomes unobservable. 4. The behaviour of the hydrolytic activity of myosin on ATP or ITP in the presence of both Ca(2+) and Mg(2+) is consistent with the explanation that the inhibition by Mg(2+) is due to the tight binding of Mg(2+) to myosin, whereas the activation by Ca(2+) is caused either by a weak binding of Ca(2+) to myosin or by CaATP(2-) or by both. PMID- 4309597 TI - Artificial substrates for prenyltransferase. AB - Four out of 16 new allylic pyrophosphates synthesized were found to be artificial substrates for liver prenyltransferase (EC 2.5.1.1). These were the trans-and the cis-3-ethyl-3-methylallyl, the 3,3-diethylallyl and the (mixture of cis and trans) 3-methyl-3-n-propylallyl pyrophosphates. The products synthesized from these substrates and isopentenyl pyrophosphate were the appropriate homo- and bishomo-farnesyl pyrophosphates. Substitution of 3,3-dimethylallyl pyrophosphate at C-2 with a methyl group destroyed its reactivity with the enzyme. Neither the unsubstituted allyl pyrophosphate nor the cis- or trans-3-methylallyl pyrophosphate could be condensed with isopentenyl pyrophosphate. Thus the simplest allylic substrate for prenyltransferase is 3,3-dimethylallyl pyrophosphate. PMID- 4309598 TI - Dietary regulation of glycolytic enzymes. IV. PMID- 4309599 TI - Organ culture of fetal rat pancreas. I. Insulin release induced by caffeine and by sugars and some derivatives. PMID- 4309600 TI - Studies on the action of insulin in isolated adipose tissue cells. II. 3',5' Nucleotide phosphodiesterase and antilipolysis. PMID- 4309601 TI - Carnitine and derivatives in embryonic chick tissue. PMID- 4309602 TI - Biosynthesis of cyanide from [2-14C-15N]glycine in Chromobacterium violaceum. PMID- 4309603 TI - Determination of enzymatically produced adenosine 3',5'-monophosphate. PMID- 4309604 TI - Synthesis and regulatory properties of an adenosine 5'-phosphate analogue, N6 methoxyadenosine 5'-phosphate. PMID- 4309605 TI - Effects of prednisoloe on esterases in heteroploid cells on human origin. PMID- 4309606 TI - Clearance studies of angiotensin II and [35S] phenylthiocarbamyl-angiotensin II in the sheep and dog. PMID- 4309607 TI - Studies on the secretion of pancreatic glucagon. PMID- 4309608 TI - Effects of tetanization on transmitter dynamics. PMID- 4309609 TI - Urethral resistance: its components and implications. I. Smooth muscle component. PMID- 4309610 TI - Ovine urolithiasis: some mineralogic and physiologic observations. PMID- 4309611 TI - The effect of silicosis on the antibacterial defense mechanisms of the murine lung. PMID- 4309612 TI - Pericarditis and myocarditis in germfr and colostrum-deprived pigs experimentally infected with a porcine polioencephalomyelitis virus. PMID- 4309613 TI - Cerebral physiology in dogs after brain-tumor induction with Schmidt-Ruppin Rous sarcoma virus: experiences with radioiodinated normal and antiviral immunoglobulin G. PMID- 4309614 TI - Electron microscopic observations on the association of viruses with membrane systems in hamster tumor cells propagated in tissue culture. PMID- 4309615 TI - Malignant lymphomas of extrathymic origin induced in rats by murine erythroblastosis virus. PMID- 4309616 TI - Central benign and malignant neural neoplasms of the jaws: a review. PMID- 4309617 TI - [Eye drops containing antibiotics and corticosteroids. Review of literature]. PMID- 4309618 TI - Pseudohypophosphatasia. PMID- 4309619 TI - Foot and mouth disease in Great Britain. PMID- 4309620 TI - The composition of nervous membranes. PMID- 4309621 TI - Ion movements in isolated preparations from the mammalian brain. PMID- 4309622 TI - Radicals induced in thymine and some of its derivatives by ionizing radiation and thermal hydrogen atoms. PMID- 4309623 TI - The bacterial content of the small intestine of young calves. PMID- 4309624 TI - [Chemical study on inhibition of calcification]. PMID- 4309625 TI - [Inapparent infections of bacterial origin]. PMID- 4309626 TI - Synaptic current at the squid giant synapse. AB - Transmission in the giant synapse of squid was studied by measuring synaptic currents in the voltage-clamped postsynaptic giant axon. These currents varied linearly with the axon's membrane potential, and showed an intercept on the voltage axis at, or near, the sodium equilibrium potential. The intercept shifted in seawater containing less sodium by even more than the shift in the sodium equilibrium potential. It is concluded that the transmitter at this synapse causes a significant change in the sodium conductance only. PMID- 4309627 TI - Cyclic adenosine monophosphate: stimulation of melatonin and serotonin synthesis in cultured rat pineals. AB - Dibutyryl cyclic adenosine monophosphate, like norepinephrine, stimulates the synthesis of labeled melatonin and serotonin from tryptophan labeled with carbon 14 by rat pineals in organ culture. Unlike norepinephrine, dibutyryl cyclic adenosine monophosphate does not enhance the accumulation of labeled tryptophan or protein within the pineal. These findings are compatible with the hypothesis that cyclic adenosine monophosphate mediates some, but not all, of the effects of norepinephrine. PMID- 4309628 TI - Oculomotor neurons in fish: electrotonic coupling and multiple sites of impulse initiation. AB - Oculomotor neurons are electrotonically coupled in three teleosts. Electron microscopy revealed axosomatic synapses with close appositions of pre- and postynaptic membranes. Similar junctions are associated with electrotonic coupling in many other cases. Stimulation of the ipsilateral eighth nerve usually initiated impulses at sites distant from the cell bodies; stimulation of the ipsilateral ophthalmic nerve initiated impulses close to the cell bodies. Electrotonic coupling may synchronize impulses arising near the, cell bodies to generate synchronous muscle contractions. Impulses arising distant from the cell bodies may lead to contractions of graded strength. PMID- 4309629 TI - Axonal transport of proteins in experimental neuropathies. AB - Axoplasmic flow of proteins is interrlupted in cats with neuropatlhy induced by acrylamide, but it is niot initerrupted in nzormlal cats and in those with neuropathy induced by tri-orthocresyl phiospliate. The proteins move from lumbosacral motor neurons along the ventral roots and from ganglion cells toward the spinal cord along the dorsal roots at about 1(1/2) millimeters per day. PMID- 4309630 TI - Rapid eye movement sleep: asleep-dependent process. PMID- 4309631 TI - [Sciatica and cauda equina syndrome due to the narrowing of the spinal canal after posterior lumbosacral arthrodesis]. PMID- 4309632 TI - [EPR-spectra of cation radicals of promazine and chlorpromazine]. PMID- 4309633 TI - Assay of arbovirus neutralizing antibody by micro methods. PMID- 4309634 TI - Effect of acclimation temperature on mitochondrial enzymes in fish. BNWL-714. PMID- 4309635 TI - A specific enzymic assay of D-glyceraldehyde and dihydroxyacetone. PMID- 4309636 TI - A rapid assay for 14C-labeled hydroxylysine in collagen and related materials. PMID- 4309637 TI - Interference by oxidized lipids in the determination of protein by the Lowry procedure. PMID- 4309638 TI - ["Uterine leioblastoma" (myoid tumors of the uterus)]. PMID- 4309639 TI - [Considerations apropos of a case of tracheal tumor]. PMID- 4309640 TI - [Contribution of the preoperative lipiodol bronchogram to the practice of thoracic surgery. II]. PMID- 4309641 TI - [On the determination of radioactively labeled diatoms in the organs]. PMID- 4309642 TI - [Changes in the concentration of thiol groups in prophase of mitosis in normal and tumor cells]. PMID- 4309643 TI - [Tissue redox enzymes in experimental iron deficiency state]. PMID- 4309644 TI - [The mitotic regime of cultures of transplantable cell line CA-SV-40-63-1]. PMID- 4309645 TI - A method for the determination of the molecular distribution of free and esterified cholesterol in serum by thin-layer chromatography. PMID- 4309646 TI - Quantitative determination of phospholipid classes in human serum by combined thin-layer chromatography and phosphorus analysis. PMID- 4309647 TI - [Structure and function of the juxtaglomerular apparatus of the kidney under normal conditions]. PMID- 4309648 TI - [Treatment of malignant cancer in children]. PMID- 4309649 TI - A method for determination of 3',5'-cyclic adenosine monophosphate based on adenosine triphosphate formation. PMID- 4309650 TI - [Evaluation of the pituitary ACTH reserve in patients irradiated for cerebral neoplasms]. PMID- 4309651 TI - [Change in the function of adrenal glands during splenectomy in patients with hemorrhagic diathesis at different methods of use of steroid hormones]. PMID- 4309652 TI - [Periodate cleavage of 3,4,16-triacetylcevine]. PMID- 4309653 TI - Phosphodiesterase of some snake and arthropod venoms. PMID- 4309654 TI - Effect of pH, temperature, antivenin and functional group inhibitors on the toxicity and enzymatic activities of Crotalus atrox venom. PMID- 4309655 TI - [Changes in the activity of endoplasmic reticulum enzymes in the ischemic rat liver]. PMID- 4309656 TI - [A morpho-biochemical study of the mitochondrial subfractions isolated from the cerebral cortex of rats]. PMID- 4309657 TI - [Malignant transformation of cells in vitro by chemical carcinogens and viruses. I. The absence of synergism at a combined action of carcinogens and polyoma virus]. PMID- 4309658 TI - [On the biological activity of provitamin D3]. PMID- 4309659 TI - [Effect of fatigue on tryptophan pyrrolase, phosphoprotein phosphatase and pyrophosphatase activities of albino rat tissues]. PMID- 4309660 TI - [On DNA fragmentation in cell nucleus due to age of the animal]. PMID- 4309661 TI - [The diagnostic value of the high heel symptom]. PMID- 4309662 TI - [On the etiology and pathogenesis of paresthetic meralgia]. PMID- 4309663 TI - [Infectious allergy. 8. Histochemical changes in various redox enzymes in cardiac muscle following sensitization with diphtheria exotoxin]. PMID- 4309664 TI - The simultaneous fluorimetric determination of corticosterone and cortisol in human plasma. PMID- 4309665 TI - Establishment of new ascites hepatomas. PMID- 4309666 TI - Immunological studies on the membrane systems of cancer cells. II. Immunochemical specificity of the mitochondria from chemical carcinogen induced carcinoma cells. PMID- 4309667 TI - Right hepatic lobectomy in children. PMID- 4309668 TI - [Nasopharyngeal cancers in Vietnam: epidemiology, clinical aspects, possible etiologic factors]. PMID- 4309669 TI - [Jugulo-tympanic glomus tumor. 2 cases]. PMID- 4309670 TI - Changes in the patterns of synthesis of ribonucleic acid species in immature rat uterus in response to oestrdiol-17 beta. AB - 1. After treatment of immature rats with diethylstilboestrol, the wet weight and RNA content of uterine tissue increased rapidly, reaching a peak at 40hr. After an initial lag of a few hours, the acid-soluble ribose and protein contents also rose to maxima at 40hr. No increase in DNA content occurred until at least 24hr. after treatment. 2. The RNA from immature rat uterus isolated at various times up to 6hr. after administration of oestradiol-17beta was labelled by injecting [(3)H]uridine and [(3)H]guanosine intraperitoneally 30min. before the animals were killed. It was fractionated on columns of kieselguhr coated with methylated serum albumin and the radioactivity in fractions corresponding to transfer RNA, 7s RNA, ribosomal RNA, Q(1)-RNA, Q(2)-RNA and DNA-like RNA was determined. 3. The radioactivity of the whole RNA increased steadily for 6hr. after hormone treatment. The earliest changes occurred in the Q(1)-RNA (ribosomal RNA precursor), whereas at longer time-intervals the radioactivity of the ribosomal RNA, 7s RNA and transfer RNA increased by four- to five-fold. The radioactivity of the DNA-like RNA increased by about 50%, but only at the longer time intervals. 4. It is concluded that one of the earliest changes in response to oestradiol treatment is a major increase in synthesis of ribosomal RNA followed later by a similar increase in synthesis of transfer RNA and by a much smaller increase in synthesis of DNA-like RNA. The change in synthesis of ribosomal RNA in immature rat uterus may represent one of the most important responses to oestradiol treatment. PMID- 4309671 TI - Control of respiration and metabolism in growing Klebsiella aerogenes. The role of adenine nucleotides. AB - 1. A rapid-sampling technique was used to obtain perchloric acid extracts of cells growing in a chemostat culture, so that meaningful values for ATP content could be obtained in spite of the fact that the turnover time for the total ATP content was about 1sec. 2. For steady-state growth, it was found that, in a glucose-limited chemostat culture, the ATP/ADP concentration ratio was approximately constant with changes in dissolved-oxygen tensions above the critical value, but fell when the culture was grown under oxygen-limited conditions and was at a minimum in anaerobically grown cultures. The steady-state ATP content was lower in cells growing under nitrogen-limited conditions with glucose in excess than in glucose-limited cells. The steady-state ATP content was independent of growth rate at growth rates over 0.1hr.(-1). 3. When the respiration rate of the cells was stimulated by lowering the oxygen tension the ATP content did not increase, indicating either an increased turnover rate of ATP or a fall in the P/O ratio. The sudden addition of extra glucose or succinate to a glucose-limited culture increased the respiration rate of the cells, but the ATP content quickly returned to the steady-state value after initial perturbations. This control over ATP content is explained in terms of regulation by adenine nucleotides of the catabolism and anabolism of glucose. An exception to this control over ATP content was found when the respiration rate was stimulated by addition of an antifoam. PMID- 4309672 TI - The influence of metal ions on the orthophosphatase and inorganic pyrophosphatase activities of human alkaline phosphatase. AB - 1. The differential effects of adding Zn(2+) and Mg(2+) on the orthophosphatase and inorganic pyrophosphatase activities of human intestinal alkaline phosphatase were studied. 2. In the presence of excess of Zn(2+), inorganic pyrophosphatase activity is inhibited. At higher concentrations of pyrophosphate, hydrolysis of this substrate takes place, but is inhibited competitively by the Zn(2+) pyrophosphate complex. This complex also acts as a competitive inhibitor of orthophosphate hydrolysis. 3. Excess of Mg(2+) also inhibits pyrophosphatase action by removal of substrate; at low concentrations, this ion activates pyrophosphatase, as is the case with orthophosphatase. 4. It is concluded that, when interactions between metal ions and pyrophosphate are taken into account, the effects of these ions are consistent with the view that alkaline phosphatases possess both orthophosphatase and inorganic pyrophosphatase activities. PMID- 4309673 TI - The subcellular distribution of 32P-labelled phospholipids, 32P-labelled ribonucleic acid and 125I-labelled odoprotein in pig thyroid slices. Effect in vitro of thyrotrophic hormone and dibutyryl-3',5'-(cyclic)-adeosine onophosphate. AB - 1. The incorporation in vitro of [(32)P]phosphate into phospholipids and RNA and of [(125)I]iodide into protein-bound iodine by pig thyroid slices incubated for up to 6hr. was studied. The subcellular distribution of the labelled products formed after incubation with radioactive precursor in the nuclear, mitochondrial, smooth-microsomal, rough-microsomal and cell-sap fractions was also studied. 2. Pig thyroid slices actively took up [(32)P]phosphate from the medium during 6hr. of incubation; the rate of incorporation of (32)P into phospholipids was two to five times that into RNA. 3. The uptake of [(125)I]iodide by the slices from the medium was rapid for 4hr. of incubation, 6-10% of the label being incorporated into iodoprotein. 4. Much of the (32)P-labelled phospholipid accumulated in mitochondria and microsomes, whereas the nuclear fraction contained most of the (32)P-labelled RNA. After 2hr. of incubation most of the (32)P-labelled cytoplasmic RNA accumulated in the rough-microsomal fraction. The major site of localization of proteinbound (125)I was the smooth-microsomal fraction, and gradually increasing amounts appeared in the soluble cytoplasm fraction, suggesting a vectorial discharge of [(125)I]iodoprotein (presumably thyroglobulin) from smooth vesicles into the colloid. 5. The addition of 0.1-0.4 unit of thyrotrophic hormone/ml. of incubation medium markedly enhanced the accumulation of (32)P-labelled phospholipids in the microsomal fractions and to a much smaller extent that of (32)P-labelled RNA without any increase in the total uptake of the label. Almost simultaneously the hormone increased the uptake of [(125)I]iodide by the slices and enhanced the accumulation of protein-bound (125)I in the smooth-microsomal fraction. 6. As a function of time of incubation, thyrotrophic hormone had a biphasic effect on [(125)I]iodide uptake and protein bound (125)I formation, the stimulatory effect being reversed after 4hr. of incubation. 7. 6-N-2'-O-Dibutyryl-3',5'-(cyclic)-AMP, but not 3',5'-(cyclic)-AMP or 5'-AMP, mimicked the action of thyrotrophic hormone on iodine uptake as well as on iodination of protein. On the other hand, the mimicry by 6-N-2'-O-dibutyryl 3',5'-(cyclic)-AMP of the stimulatory effect of thyrotrophic hormone on the formation of labelled thyroid phospholipids and RNA was only an apparent one resulting from an enhanced uptake of [(32)P]phosphate. 8. It is concluded that thyrotrophic hormone causes a co-ordinated increase in the formation or accumulation of phospholipids, RNA and iodoprotein associated with the endoplasmic reticulum, and that 6-N-2'-O-dibutyryl-3',5'-(cyclic)-AMP mimics the more rapid effects of thyrotrophic hormone on transport and metabolic functions of thyroid cells, but does not influence their slower biosynthetic responses to the hormone. PMID- 4309674 TI - Analogues of ribose 5-phosphate and 5-phosphoribosyl pyrophosphate. The preparation and properties of ribose 5-phosphorothioate and 5-phosphoribosyl 1 methylenediphosphonate. AB - 1. 5-Phosphoribosyl 1-methylenediphosphonate was isolated after reaction of ribose 5-phosphate and O-adenylyl methylenediphosphonate with 5-phosphoribosyl pyrophosphate synthetase from Ehrlich ascites-tumour cells. 2. The analogue reacted with adenine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase and nicotinamide phosphoribosyltransferase [K(m) (analogue)/K(m) (5-phosphoribosyl pyrophosphate) 0.17, 0.19 and 6.3 respectively; V(max.) (analogue)/V(max.) (5-phosphoribosyl pyrophosphate) 0.011, 0.26 and 1.1 respectively]. 3. The analogue was not a substrate for 5-phosphoribosyl pyrophosphate amidotransferase or orotate phosphoribosyltransferase. 4. Ribose 5 phosphorothioate was synthesized by allowing ribose to react with thiophosphoryl chloride in triethyl phosphate. The analogue was a substrate for 5-phosphoribosyl pyrophosphate synthetase from Ehrlich ascites-tumour cells. When this reaction was coupled to either adenine phosphoribosyltransferase or hypoxanthine phosphoribosyltransferase, adenosine 5'-phosphorothioate or inosine 5' phosphorothioate was formed respectively. PMID- 4309675 TI - The distribution of phospholipase D in developing and mature plants. AB - 1. The distribution of phospholipase D (phosphatidylcholine phosphatido hydrolase, EC 3.1.4.4) was examined in the tissues of a number of plants and seeds. 2. The highest activities were found in various swollen storage tissues of certain plants: cabbage, central stalk; cauliflower, flower; celery, swollen leaf stalk; Kohl rabi, swollen stem; carrot, root; pea and marrow, seed. 3. Appreciable activity was retained in pea seeds for at least 1 year after drying. After germination and growth in the dark the total activity present in the cotyledons and also in the whole seedling decreased. 4. In the growing pea seedling (7 days old), about 3% of the total activity was in the plumule, 9% in the root and the remainder in the cotyledons. However, the activity in the root on a dry-weight basis was higher than that in the cotyledons. In both the root and the plumule the activity on a wet- or a dry-weight basis was highest in the growing tip. 5. The activity per dry weight in the roots and aerial parts of pea plants declined to low values as growth continued, but roots struck from cuttings of mature plants showed the same high activity as found in roots from young seedlings with cotyledons attached. 6. The total phospholipids present in the cotyledons of pea seeds were depleted on germination and growth. Of the individual phospholipids, phosphatidylcholine and phosphatidylethanolamine showed the same loss in 11 days as the whole phospholipid fraction, whereas phosphatidylinositol was decreased to a greater extent and cardiolipin and phosphatidylserine were not decreased. There was no increase of phosphatidic acid, as might have been expected if the phospholipids had disappeared through phospholipase D hydrolysis. 7. It is concluded that phospholipase D in plant storage tissues and seeds may be related to the rapid growth involved in their formation rather than being necessary for the utilization of their food reserve substances. PMID- 4309676 TI - [Isolation and characterization of contractile proteins from infusoria Tetrahymena pyriformis]. PMID- 4309677 TI - [Isolation and characterization of phosphodiesterases from the cells of Zajdela ascites hepatoma]. PMID- 4309678 TI - [RNA synthesis in isolated liver and hepatoma cell nuclei and the action of olivomycin and echinomycin on it]. PMID- 4309679 TI - [Data on enzyme activity in sarcolemmic membrane of rabbit skeletal muscles]. PMID- 4309680 TI - [Preparation and alkali hydrolysis of apyrimidinic DNA]. PMID- 4309681 TI - [Effect of transforming agents on collagenase]. PMID- 4309682 TI - [Effect of adenine nucleotides on the activity of glyceraldehyde-3-phosphate dehydrogenases from different sources]. PMID- 4309683 TI - Immunofluorescence studies in human leukemia. PMID- 4309684 TI - [Statistics on brain tumors and glioma]. PMID- 4309685 TI - Further developments of International Biological Standards for anaerobic immunological substances. PMID- 4309686 TI - [Immuno-prevention of enterotoxemia in sheep]. PMID- 4309687 TI - The prevention of enterotoxaemia (pulpy kidney disease) by vaccination. PMID- 4309688 TI - [Enterotoxemia: diagnosis and prevention]. PMID- 4309689 TI - Dynamics of immunomorphological changes in the organs of chickens after immunization with BPL vaccine and after challenge with fowl plague virus. PMID- 4309690 TI - Further observations on prognostic factors in cancer of the female breast. PMID- 4309691 TI - Atypical epithelial hyperplasia associated with breast cancer and fibrocystic disease. PMID- 4309692 TI - Mucous gland tumors of paranasal sinuses. PMID- 4309693 TI - Treatment of pulmonary metastatic disease with radiation therapy and adjuvant actinomycin D. Preliminary observations. PMID- 4309694 TI - Adenoid cystic carcinoma of the breast. An analysis of 21 cases. PMID- 4309695 TI - Development of myeloblastoma with massive breast and ovarian involvement during remission in acute leukemia. PMID- 4309696 TI - Conversion of D-mannuronolactone into D-mannaric acid in mammalian systems. PMID- 4309697 TI - [New endocrine disorders attracting current interest--anterior pituitary gland]. PMID- 4309698 TI - [New endocrine disorders attracting current interest--adrenal system]. PMID- 4309699 TI - [Case of Cushing's syndrome caused by pancreatic tumor]. PMID- 4309700 TI - [Functional classification and postnatal development of the anterior pituitary cells in mice]. PMID- 4309701 TI - [Relationship between ultrastructure and function of the anterior pituitary gland in birds]. PMID- 4309702 TI - [Special studies on endocrine diseases--Addison's disease]. PMID- 4309703 TI - [Development of methods for determination of steroids using impregnant thin layer chromatography]. PMID- 4309704 TI - Serotonin-induced swelling of rat liver mitochondria. PMID- 4309705 TI - Granular localization of corticotropin-releasing activity in horse hypophysial stalk homogenate. PMID- 4309706 TI - Electrom microscopic study of the anencephalic adenohypophysis with reference to the adrenocorticotrophs and their correlation with the functional differentiation of the hypothalamus during the foetal life. PMID- 4309707 TI - Pyrophosphate enhancement of hypocalcemic effect of thyrocalcitonin in rat. PMID- 4309708 TI - ACTH secretion from the pituitary transplanted in apposition with the adrenal cortex under the renal capsule. PMID- 4309709 TI - Pituitary regulation of preovulatory estrogen secretion in the rat. PMID- 4309710 TI - Effect of cold exposure on amino acid transport and incorporation into rat anterior pituitary in vitro. PMID- 4309711 TI - Effects of chloroquine pretreatment on lethal dose of morphine and on morphine metabolism in rats. PMID- 4309712 TI - Haemorrhage and the sensitivity of canine mesenteric vascular bed to angiotensin and norepinephrine. PMID- 4309713 TI - [Effects of cyclic 3', 5'-AMP and theophylline on the smooth muscle and heart preparation]. PMID- 4309714 TI - Cytochemical demonstration of nucleoside phosphatase activity in myelinated nerve fibers of the rat. PMID- 4309715 TI - Characteristics of antibody to a limited antigenic stimulus. PMID- 4309716 TI - Continuous splitting off of phosphate from phosvitins by phosphoprotein phosphatase. PMID- 4309717 TI - Inhibitory effect of substrate analogs on isopentenyl pyrophosphate isomerase and prenyltransferase. PMID- 4309718 TI - Isolation and characterization of enzymes with nicking action from phage T4 infected Escherichia coli. PMID- 4309719 TI - Localization of cytochrome c peroxidase in anaerobically grown yeast cells. PMID- 4309720 TI - Studies on oxygenases. I. Comparative studies on 3,4-dihydroxyphenylacetate-2,3 oxygenase and pyrocatechase by electron spin resonance spectroscopy. PMID- 4309721 TI - Isolation and comparison of phosphorylase b isozymes in pig heart. PMID- 4309722 TI - Transport of calcium into adipose tissue in response to adrenocorticotropic hormone. PMID- 4309723 TI - The growth requirements of Haemophillus aphrophillus. PMID- 4309724 TI - A comparative study of standard methods and organ culture for the isolation of respiratory viruses. PMID- 4309725 TI - The effect of cyclophosphamide on Sendai virus infection of mice. PMID- 4309726 TI - The effect on drinking in the rat of intravenous infusion of angiotensin, given alone or in combination with other stimuli of thirst. AB - 1. Intravenous infusion of angiotensin causes rats which are in water balance to drink water.2. The mean amount of angiotensin needed to initiate drinking was 29.1 +/- 4.6 mug/kg (S.E. of mean) in twenty normal rats, and 15.7 +/- 2.1 mug/kg in thirty-four nephrectomized rats.3. The nephrectomized rat is therefore more sensitive to this action of angiotensin than the rat with intact kidneys.4. The rates of infusion (0.05-3.0 mug/kg(-1) min(-1)) which cause drinking are comparable to those used to produce other effects in rats.5. Angiotensin restores the drinking response of the nephrectomized rat subjected to caval ligation to a value similar to that obtained in the uninfused normal rat subjected to caval ligation.6. The effects of angiotensin and hypertonic saline on drinking are additive when both substances are administered to nephrectomized rats.7. These experiments provide further support for the view that the renin-angiotensin system is concerned in extracellular thirst. PMID- 4309727 TI - A possible role of acetylcholine in the central control of body temperature in sheep. PMID- 4309728 TI - The rate of penetration of K+ into the intertransverse caudal muscles of the rat. PMID- 4309729 TI - Interferon-like inhibitor detected in culture fluids of normal HeLa cells. PMID- 4309730 TI - [Congenital hemolytic anemias with glutatione metabolism disorders (excluding glucose-6-phosphate dehydrogenase deficiency)]. PMID- 4309731 TI - [Enzyme deficit of the Embden-Meyerhof pathway]. PMID- 4309732 TI - [Measurements of RISA uptake in cerebral tumors and its significance for histological diagnosis]. PMID- 4309733 TI - Studies on phenolic steroids in human subjects. XII. In vitro metabolism of estradiol-6,7-3H-3-glucosiduronate-14C and of estrone-6,7-3H-glucosiduronate by human placental estradiol-17beta-dehydrogenase. PMID- 4309734 TI - The tensile strength of wounds and factors that influence it. PMID- 4309735 TI - [Infectious enterotoxemia of sheep in the Mongolian People's Republic]. PMID- 4309736 TI - [The ontogenesis of viruses of Aujeszky's disease and fowl pseudoplague]. PMID- 4309737 TI - [Comparative assessment of the use of vaccine against fowl pseudoplague of strains B1 and La-Sota]. PMID- 4309738 TI - [Insuloma]. PMID- 4309739 TI - [The formation of corticosteroids in the administration of cetamiphen]. PMID- 4309740 TI - [An outbreak of adenoviral pneumonia]. PMID- 4309741 TI - [A comparative study of the antigenic and immunogenic properties of the anatoxin of Cl. perfringens, concentrated and purified by various methods]. PMID- 4309742 TI - Studies on fibrinolytic enzymes in the field of obstetrics and gynecology, especially tissue activator. 4. Antifibrinolytic action of sex hormones, especially a conjugated estrogen (Premarin) and its application. PMID- 4309743 TI - Adenoviruses of animals other than man. PMID- 4309744 TI - The etiology and control of urolithiasis. PMID- 4309745 TI - [Physiology, enzymology, biochemistry and pharmacology of the beta cells in the islets of Langerhans of the pancreas]. PMID- 4309746 TI - [Use of silica gel and microorganisms for growing Niphargus virei (hypogeal Crustacea Amphipoda) in artificial media]. PMID- 4309747 TI - Glycerylphosphorylcholine diesterase: effects of metal-binding agents. PMID- 4309748 TI - Kinetic studies on the interaction of TMPD with cytochrome c and cytochrome c oxidase. PMID- 4309749 TI - Polypoid adenocarcinoma of the cervical esophagus. PMID- 4309750 TI - Temperature and the regulation of enzyme activity in poikilotherms. Properties of lungfish fructose diphosphatase. AB - 1. The properties of fructose diphosphatase from liver of South American lungfish (Lepidosiren paradoxa) were examined. 2. Saturation curves for substrate (fructose diphosphate) and both cofactors (Mn(2+) and Mg(2+)) are sigmoidal and Hill plots of these results suggest about 2 interacting substrate and cofactor sites/molecule of enzyme. 3. Mn(2+) is an efficient positive modulator of the enzyme and K(a) for Mn(2+) is about 20-30-fold lower than the K(a) for Mg(2+). 4. Lungfish fructose diphosphatase is inhibited by low concentrations of AMP, and the affinity of the enzyme for AMP is insensitive to temperature. 5. The affinities of fructose diphosphatase for fructose diphosphate and Mn(2+) appear to be dependent on temperature, whereas affinity for Mg(2+) is temperature independent. 6. The pH optimum of the enzyme depends on the presence of the particular cofactor. As pH increases, the K(a) values of both cations are lowered, maximum velocities are increased and the saturation curves for cofactor become hyperbolic. 7. The possible roles of these ions, pH and substrate in the modulation of fructose diphosphatase and gluconeogenic activity in the lungfish are discussed in relation to aestivation and temperature adaptation. PMID- 4309751 TI - Characteristics of cells dissociated from mouse mammary glands. I. Method of separation and morphology of parenchymal cells from lactating glands. PMID- 4309752 TI - [Data on the etiology of primary herpetic gingivostomatitis]. PMID- 4309753 TI - [Labelling of essential amino acid residues of pig heart lactate dehydrogenase with (carbonyl-14C)3-(2-bromoacetyl) pyridine]. PMID- 4309754 TI - Non-degraded incorporation of highly polymerized DNA and isolated metaphase chromosomes into cultured mammalian cells and replication of the incorporated heterologous chromosomes in the cultured cells. PMID- 4309755 TI - [Experimental contribution to the relationship between kidney and erythropoiesis: PAS-positive erythroblasts in the bone marrow of bilaterally nephrectomized rats]. PMID- 4309757 TI - Ischio-rectal fossa tumour. PMID- 4309756 TI - [Determination of the angiotensinase-(aminopeptidase-)activity in blood using a DPN. H-dependent optical test]. PMID- 4309759 TI - [Primary aldosteronism (Conn's syndrome)]. PMID- 4309760 TI - [Preparations for treatment of hypoparathyreoidism (antitetanics). 36]. PMID- 4309761 TI - [The effect of corticosteroid hormones on cerebral metabolism (review of the literature)]. PMID- 4309762 TI - [Hyperaldosteronism and the renin-angiotensin system]. PMID- 4309763 TI - [Barr bodies and tumor sex in breast neoplasms]. PMID- 4309764 TI - [Contribution to the diagnosis and therapy of malignant bone and soft tissue neoplasms. Treated cases from 1960-1965]. PMID- 4309765 TI - [Activation of alkaline and acid phosphatase in ganglion cells following x irradiation on the guinea pig brain (200 kV)]. PMID- 4309766 TI - Histochemical investigation of the mucosa of the exteriorized small intestine of the rat exposed to x-radiation. PMID- 4309767 TI - Cancer of the breast in women. A retrospective clinical study of 2416 cases. PMID- 4309768 TI - [To which extent ar x-rays responsible for the development of malignant diseases in children? II. Ossification disorders of the hand bones in leukemic children]. PMID- 4309769 TI - Intracellular distribution of respiratory enzymes in hamster and rat brown fat. ANL-7535. PMID- 4309772 TI - Angiography in primary hepatic tumours in children. PMID- 4309771 TI - [Case of ketotic hypoglycemia]. PMID- 4309773 TI - Angiography in Wilms' tumour. PMID- 4309774 TI - Renal pelvis appearances in nephro- and neuroblastomas. Diagnostic value of true lateral projections. PMID- 4309775 TI - Mandibular erosion in tumours of the major salivary glands. PMID- 4309776 TI - Down's syndrome: a study of sleep patterns related to level of mental retardation. PMID- 4309777 TI - "Panta'rhei"--and so flow our nerves. PMID- 4309778 TI - Flurandrenolone (Cordran) tape and carbohydrate metabolizing enzymes. Use in the epidermis of people with psoriasis. PMID- 4309779 TI - Histogenesis of skin appendage tumors. PMID- 4309780 TI - Eczema herpeticum. PMID- 4309781 TI - Heterogeneity of paramagnetic species in two iron-sulfur proteins: Clostridium pasteurianum ferredoxin and milk xanthine oxidase. PMID- 4309782 TI - The nature of the intramolecular cross-link in collagen. PMID- 4309783 TI - Hormone stimulation of ketogenesis in rat liver homogenates. PMID- 4309784 TI - Polymerization of 5'-desoxyribonucleotides with beta-imidazolyl-4(5)-propanoic acid. PMID- 4309785 TI - Studies on non-heme iron proteins and the piericidin A binding site of submitochondrial particles from Candida utilis cells grown in media of varying iron concentrations. PMID- 4309786 TI - Differences in RNA from rat liver and hepatoma revealed by DNA-RNA hybridization. PMID- 4309787 TI - Substrate induced spin state changes in cytochrome P-450. PMID- 4309788 TI - Sphingolipids of animal nervous tissue. I. A comparative study of polar lipids sphingosine bases. PMID- 4309789 TI - Inhibition of sterol synthesis in vitro by metabolites of phenylalanine. PMID- 4309790 TI - Enzymatic hydrolysis of glycerophosphoryl esters. II. Cleavage of d-glycerol-1 phosphoryl-L-glycerol. PMID- 4309791 TI - Studies of the heme components of cytochrome c oxidase by EPR spectroscopy. PMID- 4309792 TI - One-electron transfer reactions in biochemical systems. IV. A mixed mechanism in the reaction of milk xanthine oxidase with electron acceptors. PMID- 4309793 TI - Amniotic fluid in a case of multiple congenital anomalies. PMID- 4309794 TI - Tumor induction in C57BL-6 mice by a single administration of cycasin. PMID- 4309795 TI - Influence of toyocamycin on RNA synthesis in chick embryo cells noninfected and infected with strain MC29 avian leukosis virus. PMID- 4309796 TI - Studies on chemical carcinogens. IX. Homolytic degradation of O,O'-Diacetyl-4 hydroxyaminoquinoline 1-oxide (1-acetoxy-4-acetyloxyimino-4-dihydroquino- line). PMID- 4309797 TI - Lysosomal enzymes in aquatic species. I. Distribution and particle properties of muscle lysosomes of the goldfish. PMID- 4309798 TI - A comparative study of gamma-aminobutyric acid uptake in crustacean nerve-muscle preparations. PMID- 4309799 TI - Studies of long term administration of aflatoxin to rats as a natural food contaminant. PMID- 4309800 TI - Myocardial adenyl cyclase: activation by thyroid hormones and evidence for two adenyl cyclase systems. AB - The mechanism responsible for the hyperdynamic circulatory state in hyperthyroidism has not been defined. Although certain cardiac manifestations resemble those caused by excessive adrenergic stimulation, recent evidence suggests that thyroid hormone exerts an effect on the heart that is independent of the adrenergic system. Since the inotropic and chronotropic effects of norepinephrine appear to be mediated by activation of adenyl cyclase, the possibility that thyroxine and triiodothyronine are also capable of activating adenyl cyclase was examined in the particulate fraction of cat heart homogenates.L-thyroxine and L-triiodothyronine increased the conversion of adenosine triphosphate-(32)P (ATP-(32)P) to cyclic 3',5'-adenosine monophosphate (32)P (3',5'-AMP-(32)P) by 60 and 45% respectively (P < 0.01). A variety of compounds structurally related to the thyroid hormones, but devoid of thyromimetic activity did not activate adenyl cyclase: these included 3,5-diiodo L-thyronine, L-thyronine, 3,5-diiodotyrosine, monoiodotyrosine, and tyrosine. D thyroxine activated adenyl cyclase and half maximal activity was identical to that of the L-isomer. Although the beta adrenergic blocking agent propranolol abolished norepinephrine-induced activation of adenyl cyclase, it failed to alter activation caused by thyroxine. When maximal concentrations of L-thyroxine (5 x 10(-6) moles/liter) and norepinephrine (5 x 10(-5) moles/liter) were incubated together, an additive effect on cyclic 3',5'-AMP production resulted. THIS INVESTIGATION DEMONSTRATES: (a) thyroid hormone is capable of activating myocardial adenyl cyclase in vitro and (b) this effect is not mediated by the beta adrenergic receptor. Moreover, the additive effects of norepinephrine and thyroxine suggest that at least two separate adenyl cyclase systems are present in the heart, one responsive to norepinephrine, the other to thyroid hormone. These findings are compatible with the hypothesis that the cardiac manifestations of the hyperthyroid state may, in part, be caused by the direct activation of myocardial adenyl cyclase by thyroid hormone. PMID- 4309801 TI - Hormonal regulation of lipolysis and phosphorylase activity in human fat cells. AB - Prostaglandin E(1) (PGE(1)) at a concentration of 1 ng/ml antagonized theophylline, and norepinephrine induced release of glycerol and free fatty acids (FFA) in human fat cell preparations. Insulin at higher doses also inhibited theophylline-stimulated lipolysis. The N(6)-2-0'dibutyryl derivative of cyclic adenosine monophosphate (DCAMP) stimulated lipolysis. Prostaglandin E(1) did not significantly inhibit the lipid mobilizing effects of DCAMP. Changes in glycogen phosphorylase activity after treatment with theophylline, norepinephrine, DCAMP, and PGE(1) paralleled those of lipolysis. These results suggest that in man as in experimental animals lipolysis and phosphorylase activity are regulated through processes involving cyclic AMP and that PGE(1) appears to exert its antilipolytic effect in human fat cells, as in rat fat cells, by interfering at the level of adenyl cyclase with the accumulation of cyclic AMP. PMID- 4309803 TI - Assessment of hypothalamic-pituitary-adrenal function in the geriatric age group. PMID- 4309802 TI - Pseudohypoparathyroidism: defective excretion of 3',5'-AMP in response to parathyroid hormone. AB - Urinary excretion of cyclic adenosine 3',5'-monophosphate (3',5'-AMP) was tested in normal subjects and patients with pseudohypoparathyroidism, idiopathic hypoparathyroidism, surgical hypoparathyroidism, and pseudopseudohypoparathyroidism under basal conditions and after a 15 min infusion of purified parathyroid hormone. Basal excretion of the nucleotide was less than normal in the patients with hypocalcemic disorders and greater than normal in pseudopseudohypoparathyroidism. Parathyroid hormone caused a marked increase in excretion of 3',5'-AMP in all subjects except those with pseudohypoparathyroidism; nine patients with this disorder did not respond to the hormone and four showed a markedly deficient response. Radioimmunoassay showed that parathyroid hormone circulated in increased amounts in plasma from patients with pseudohypoparathyroidism and became undetectable when serum calcium was increased above 12 mg/100 ml. Suppression of parathyroid hormone secretion by induction of hypercalcemia did not alter the deficient response to exogenous hormone. The results indicate that: (a) parathyroid hormone circulates in abnormally high concentrations in pseudohypoparathyroidism and secretion of the hormone responds normally to physiological control by calcium; (b) testing urinary excretion of 3',5'-AMP in response to infusion of purified parathyroid hormone appears to be an accurate and sensitive index for establishing the diagnosis of pseudohypoparathyroidism; and (c) the metabolic defect of the disorder can be accounted for by a lack of or defective form of parathyroid hormone-sensitive adenyl cyclase in bone and kidney. PMID- 4309804 TI - The gibbon (Hylobates lar); a new primate host for Herpesvirus hominia. I. A natural epizootic in a laboratory colony. PMID- 4309805 TI - Monkey pox. IV. Modification of disease pattern by antilymphocytic sera. PMID- 4309806 TI - Herpes simplex infection of the female genital tract. II. Association of cytopathic effect in cell culture with site of infection. PMID- 4309807 TI - Australia antigen and viral hepatitis. PMID- 4309808 TI - [Study of adrenal estrogen]. PMID- 4309809 TI - Alkaline phosphodiesterase activity of goat brain cortex ribosomes. PMID- 4309810 TI - The biosynthesis of triiphosphoinositide by purified myelin of peripheral nerve. PMID- 4309811 TI - Cytochrome oxidase activity in platelet-free preparations of Plasmodium knowlesi. PMID- 4309812 TI - Succinic dehydrogenase and cytochrome oxidase in the liver of mice infected with Trypanosoma cruzi. PMID- 4309814 TI - Protective effect of interferon and polyacrylic acid in newborn mice infected with a lethal dose of vesicular stomatitis virus. PMID- 4309815 TI - Pulmonary activation of synthetic angiotensin I. PMID- 4309816 TI - Effects of neurohypophyseal hormones, theophylline and nucleotides on the smooth muscle of the toad bladder. PMID- 4309817 TI - Retained products of conception. Histologic viability of placental polyps. PMID- 4309818 TI - Radiation therapy of brain-stem tumors. PMID- 4309819 TI - Megavoltage radiation therapy and lymphangiography in ovarian cancer. PMID- 4309820 TI - Malignant tumors of the ovary managed with postoperative megavoltage irradiation. PMID- 4309821 TI - Herpetic sciatica. PMID- 4309822 TI - Postirradiation malignant neoplasms of the uterine fundus. PMID- 4309823 TI - The relationship between the transport of glucose and cations across cell membranes in isolated tissues. V. Stimulating effect of ouabain, K+-free medium and insulin on efflux of 3-O-methylglucose from epidimal adipose tissue. PMID- 4309824 TI - Adenine nucleotide metabolism of blood platelets. V. Subcellular localization of some related enzymes. PMID- 4309825 TI - The effect of acute exercise on amino acid incorporation into mitochondria of rabbit tissues. PMID- 4309826 TI - RNA synthesis in Taper hepatoma and mouse-liver cells. PMID- 4309827 TI - Altered transfer RNA methylase patterns induced by an avian oncogenic virus. PMID- 4309828 TI - The nature of inhibitors of DNA synthesis in rat-liver hepatoma cells. PMID- 4309829 TI - Erythrocytic enzyme defects in infancy. Biochemistry of erythrocytes of the newborn. PMID- 4309830 TI - Polysyndactyly, a new mutant gene in the mouse. PMID- 4309831 TI - Humoral immunity factors to parainfluenza viruses type 1, 2 and 3 in infants under the age of one year. PMID- 4309832 TI - Course of air-borne infection caused by B virus (Herpesvirus simiae). 3. Immunofluorescence findings in some organs of rabbits infected with large doses of B-virus aerosol. PMID- 4309833 TI - Effect of 1 percent phenol on several bacterial and viral species. PMID- 4309834 TI - Dynamics of incidence of antibiotic-(chemotherapeutic-) resistant E. coli in pigs and types of polyresistance of the isolated strains depending on addition of aureovit12 C20 to food. PMID- 4309835 TI - Methaqualone (Quaalude-300) and REM sleep. PMID- 4309836 TI - Time cycle for intracellular synthesis of mirine leukaemia virus. PMID- 4309837 TI - Morphology of ascites sarcoma RAB I of the mouse. PMID- 4309838 TI - [Symptom complex of acromegaly and Itsenko-Cushing disease of primary diencephalic genesis]. PMID- 4309839 TI - Cytomegalovirus infection in infancy: report of 9 cases and brief review of the literature. PMID- 4309840 TI - Cancer of the lung in Natal Bantu--a new cancer problem. A review of 472 cases, 1964-1966. PMID- 4309841 TI - Inactivation of the bovine mammillitis herpesvirus by disinfectants. PMID- 4309842 TI - Association of herpes-like virus infection with infectious mononucleosis. PMID- 4309843 TI - Factors affecting urate excretion following diuretic administration in man. PMID- 4309844 TI - Cushing's syndrome with a paradoxical response to dexamethasone. PMID- 4309845 TI - Persistent antidiuresis with hypoaldosteronism and sodium wasting in hypopituitarism. PMID- 4309846 TI - Bilateral multiple otosclerotic foci and endolymphatic hydrops, histopathological case report. PMID- 4309847 TI - Antiviral activity of 9-beta-D-arabinofuranosyladenine. 3. Reduction in evidence of encephalitis in treated herpes Simplex-infected hamsters. PMID- 4309848 TI - Antiviral activity of 0-beta-D-arabinofuranosyladenine. IV. Activity against intracerebral herpes simplex virus infections in mice. PMID- 4309849 TI - Antiviral activity of 9-beta-D-arabinofuranosyladenine. V. Activity against intracerebral Vaccinia virus infections in mice. PMID- 4309850 TI - Inhibitory effect of statolon on murine leukemia and sarcoma viruses in cell culture. PMID- 4309851 TI - Atraumatic nasal biopsy for studies of respiratory virus infection in volunteers. PMID- 4309852 TI - Incidence of cytomegalovirus infection in uremic patients. PMID- 4309853 TI - Effect of the nutritional environment on the development of resistance to polymyxin B in Pseudomonas aeruginosa and its prevention by atabrine. PMID- 4309854 TI - 25-hydroxycholecalciferol. The probable metabolically active form of vitamin D3: its identification and subcellular site of action. PMID- 4309855 TI - The nature of vitamin D resistance of patients with chronic renal disease. PMID- 4309856 TI - Clinical experience with human growth hormone immunoassay by a two-antibody method. PMID- 4309857 TI - Acanthosis nigricans and obesity, an endocrine abnormality? PMID- 4309858 TI - [Effects of vaious substances on the myocardial polarographic oxygen in the dog]. PMID- 4309859 TI - Intermolecular disulfide oss-linkages in the collagen from the muscle layer of Ascaris lumbricoides. PMID- 4309860 TI - Collagen-protein-polysaccharide interactions in human intervertebral disc. PMID- 4309861 TI - On the binding of adrenocorticotropin to proteins during isolation. PMID- 4309862 TI - Aglossia congenita with bony fusion of the jaws. PMID- 4309863 TI - Adrenal function during topical oral corticosteroid treatment. AB - Plasma cortisol (hydrocortisone) levels were measured in 42 subjects before and during administration of topical oral corticosteroids. Topical administration of 0.3-0.4 mg. of betamethasone disodium phosphate daily caused partial suppression of adrenal function in 8 out of 10 subjects tested. The adrenal function remained normal in 14 patients treated with 10 mg. of hydrocortisone hemisuccinate daily for periods of up to three years. Betamethasone 17-valerate also failed to cause adrenal suppression in doses of 0.4 mg. per day in 17 patients. The adrenal glands failed to respond normally to stimulation with Synacthen (tetracosactrin) in selected subjects with depressed plasma cortisol levels. Therapeutic doses of topical oral hydrocortisone hemisuccinate and betamethasone 17-valerate may be used in adults with oral lesions without fear of affecting adrenal function. Betamethasone disodium phosphate, however, should be avoided, as it may cause adrenal suppression. PMID- 4309864 TI - [Survival beyond 3 years from the ill effects of medically treated bronchial carcinomas]. PMID- 4309865 TI - Metabolic differentiation of distinct muscle types at the level of enzymatic organization. PMID- 4309866 TI - The subcellular distribution of lysophospholipase in bovine adrenal medulla. PMID- 4309867 TI - A quantitative study of the biosynthesis of cytochrome c. PMID- 4309868 TI - Spectroscopic differentiation of the electron-accepting sites in fungal laccase. Association of a near ultraviolet band with a two electron-accepting unit. PMID- 4309869 TI - Regulation of the level of key enzymes of glycolysis and gluconeogenesis in liver. PMID- 4309870 TI - The proption of the incorporation of leucine into albumin to that into totaprotein in rat liver and hepatoma Morris 5123 TC. PMID- 4309871 TI - Thrombosthenin M. Purification and interaction with thrombin. PMID- 4309872 TI - An optical rotatory dispersion vestigation of fungal laccase. PMID- 4309873 TI - Koch's phenomenon involving the flexor tendon sheath. Adjuvant-induced tenosynovitis in man. PMID- 4309874 TI - Ionic permeability of the inhibitory postsynaptic membrane of lobster muscle fibers. AB - Reversal potentials (E(IPSP)) of the inhibitory postsynaptic potential and the membrane resting potentials (E(M)) of lobster muscle fibers were determined with intracellular recording under a variety of ionic conditions. E(IPSP) is solely dependent on the electromotive force of anionic batteries; i.e., on the electrochemical gradient for a "mobile" fraction of intracellular Cl (Cl(i)) which is considerably smaller than the total intracellular Cl. The active inhibitory membrane is more permeable to certain "foreign" anions in the order NO(3) > SCN > Br > Cl. The membrane is impermeable to BrO(s), isethionate, and methylsulfate, but is slightly permeable to acetate and propionate. The level of Cl(i) appears to be determined in part by some active (pump?) process and most of the anions studied appear to interfere with the steady-state level of Cl(i). PMID- 4309875 TI - Identification of vitamin D3 in human skin. PMID- 4309876 TI - Influence of diethylaminoethyl-dextran on uptake and degradation of polyoma virus deoxyribonucleic acid by mouse embryo cells. AB - The uptake of (32)P-labeled polyoma virus deoxyribonucleic acid (DNA) (I and II + III) by mouse embryo cells was increased from two- to fivefold in the presence of 500 mug of diethylaminoethyl-dextran (DEAE-D) per ml. This concentration of DEAE D gives maximal enhancement of infectivity; however, the increase is many thousand-fold. As the DEAE-D concentration was increased from 0 mug/ml, uptake and infectivity increased to flat maxima and then decreased in a similar manner, except that at low DEAE-D concentrations uptake was relatively much greater than infectivity. Several other polycations also increased DNA uptake but did not enhance infectivity, and uptake of viral DNA was unaffected by the presence of mouse DNA, although infectivity was reduced. Thus, increased uptake is not the sole basis for the enhancement of infectivity produced by DEAE-D. The possibilities that DNA complexed with DEAE-D penetrates more rapidly or is stabilized against degradation do not completely account for enhancement since complexes formed in mixtures of DNA and DEAE-D, which sedimented heterogeneously from 40 to 60S, were infectious only for monolayers treated with DEAE-D. A more likely factor in enhancement is inhibition of the cellular nuclease activity detected, since virus DNA exposed to cells was much more degraded in the absence than in the presence of DEAE-D. The nuclease activity produced single-strand breaks in double-stranded DNA. Treatment of monolayers with deoxyribonuclease after adsorption of DNA in the presence of DEAE-D reduced cell-associated radioactivity by about 70%, although the number of plaques formed was not affected. In the absence of DEAE-D, 90 to 100% was removed by deoxyribonuclease. Thus, in both cases most of the DNA was adsorbed extracellularly. The greater deoxyribonuclease-resistant fraction in the presence of DEAE-D would be consistent with another possibility: that enhancement results from an increase in DNA penetration rate due to some action of DEAE-D on the cell. PMID- 4309877 TI - Site of host restriction of simian virus 40 mutants in an established African green monkey kidney cell line. AB - A previously described large-plaque morphology mutant of SV40 (SV-L) in primary African green monkey kidney (AGMK) cells has been shown to be restricted in the established AGMK line CV-1. The site of restriction is an early step in infection, involving the virus particle. A block in penetration or uncoating has been tentatively proposed. Restriction is observed in a number of other established lines, including monkey, human, and mouse. Independent large-plaque mutants were isolated in AGMK and their properties were compared with SV-L (temperature restriction, host restriction, and virion antigen). They can be separated into two classes. Both are restricted on CV-1, though to a lesser degree than SV-L. Further-more, both are coat mutants as determined by immunological analysis of their virions, suggesting a relationship between coat mutants associated with large-plaque morphology in AGMK and host restriction in established cell lines. Temperature restriction is seen with one but not the other of the mutants. PMID- 4309879 TI - Analysis of the ribonucleic acid of murine leukemia virus. AB - Cells producing the Rauscher strain of murine leukemia virus (MLV) were exposed to (3)H-uridine, and labeled virus was collected at hourly intervals. Ribonucleic acid (RNA) extracted from virions (vRNA) had a characteristic single peak when analyzed by electrophoresis in polyacrylamide-agarose composite gels. Exposure of vRNA to dimethyl sulfoxide, urea, formaldehyde, or heat altered the mobility to a faster moving form (vRNA'). This vRNA' sedimented more slowly than native vRNA in sucrose gradients. Incubation of labeled virions at 37 C resulted in fragmentation of viral RNA which was detectable only after denaturation. Also, large differences in the temperature required for the change from vRNA to vRNA' were seen with alterations in NaCl concentration. These experiments demonstrate that the vRNA of MLV is held in a specific conformation by hydrogen bonds distributed over a large part of the molecule. The possibility that an undefined factor is associated with viral RNA is discussed. PMID- 4309878 TI - Biological effects of substituting cytosine for 5-hydroxymethylcytosine in the deoxyribonucleic acid of bacteriophage T4. AB - Previous work from this laboratory has shown that the cytosine-containing T4 deoxyribonucleic acid (DNA) made by deoxycytidine triphosphatase (dCTPase) amber mutants is extensively degraded, and that nucleases controlled by genes 46 and 47 participate in this process. In this paper, we examine other consequences of a defective dCTPase. Included are studies of DNA synthesis and phage production, and of the control of both early and late protein synthesis after infection of Escherichia coli B with various T4 mutants defective in genes 56 (dCTPase), 42 (dCMP hydroxymethylase), 1 (deoxynucleotide kinase), 43 (DNA polymerase), 30 (polynucleotide ligase), 46 and 47 (DNA breakdown) or e(lysozyme). By varying the temperature of infection with a temperature-sensitive dCTPase mutant, we have been able to control intracellular dCTPase activity, and thus vary the cytosine content of the phage DNA. We have produced and characterized viable T4 phage in which cytosine replaces 20% of the 5-hydroxymethylcytosine (HMC) in the DNA. We present evidence which suggests that intact, cytosine-containing T4 DNA is much less efficient than is normal T4 DNA in directing the synthesis of tail-fiber antigen. Lysozyme production is much less affected by progressively decreasing dCTPase activity; however, complete substitution of cytosine is correlated with a depression of lysozyme synthesis greater than expected from the defective synthesis of DNA. Low but significant lysozyme synthesis is observed late after infection of E. coli B with T4 amber mutants defective in a number of genes controlling DNA synthesis. The "20% cytosine" T4 phage, once produced, can initiate an apparently normal infection at permissive temperatures; the synthesis of early enzymes, DNA, and phage does not appear to be impaired. Two roles for HMC in T4 DNA have been indicated previously: (i) involvement in host-controlled restriction of the phage, in which glucosylation of the hydroxymethyl group plays a crucial role (16, 29, 53, 58), and (ii) protection of vegetative DNA against phage-controlled nucleases, a protection not dependent on glucosylation (41, 66, 67). A third role is suggested by our present results: transcription of at least some late genes can occur only from HMC-containing DNA and not from cytosine containing DNA. PMID- 4309880 TI - Electron microscopic observations on the ribonucleic acid of murine leukemia virus. AB - The ribonucleic acid (RNA) of murine leukemia virus (MLV) Rauscher strain was observed by the aid of electron microscopy with the use of the protein monolayer technique. RNA was observed directly after release from virus particles or after isolation by sedimentation in sucrose density gradients. Molecules were found in an extended linear form. Many of the RNA filaments released by detergent treatment contained curled regions, suggesting the linear filaments were originally coiled within the virus particle. The relationship of the curled areas to the containment of the RNA within the virus particle is discussed, and a mechanism for the inclusion of RNA in the budding virion is proposed. Treatment of the extended MLV-RNA with dimethyl sulfoxide resulted in the collapse of the molecule forming a tangled complex. Treatment with urea or heating at 50 C in 3 mm NaCl also produced this effect. Also under the conditions in which MLV-RNA was linear, RNA from Rous sarcoma virus also was linear, but Newcastle disease virus RNA and ribosomal RNA of rat liver had collapsed structures. The results indicated that the RNA of MLV, and perhaps other RNA-containing tumor viruses, has a specific unique conformation dependent upon hydrogen bonds. PMID- 4309881 TI - Molecular weight of poliovirus ribonucleic acid. AB - Purified poliovirus single- and double-stranded ribonucleic acids (RNA) were examined by electron microscopy. The length of both molecules was found to be 2.37 mum. The uncorrected sedimentation coefficient for single-stranded RNA is 33S, as compared to 27S for the RNA of tobacco mosaic virus. It is calculated from these results that the molecular weight of the sodium form of poliovirus is 2.6 x 10(6) daltons. PMID- 4309882 TI - Replication of canine herpesvirus. II. Virus development and release in infected dog kidney cells. AB - The studies reported in this paper demonstrate that, although canine herpesvirus differs from other herpesviruses in that it is characterized by a restricted host range, the pattern of virus development in the permissive host closely resembles that previously described for herpes simplex virus. These experiments also reveal the formation in the infected dog kidney cells of a system of tubules and channels in which virions accumulate. It is suggested that these membrane-bound structures serve to protect enveloped virus from being uncoated in the cytoplasm and function in virus release from the infected cells. PMID- 4309883 TI - Mengovirus-induced cytopathic effect in L-cells: protective effect of interferon. AB - The effect of interferon on mengovirus-induced cytopathic effect (CPE) in L cells, the cut-off of host-cell protein synthesis, and production of mature virus were found to be dependent on the concentration of interferon. CPE and inhibition of host protein synthesis were not affected until the concentration of interferon was increased 100-fold over that required to reduce viral yields by 90%. PMID- 4309884 TI - Entry and release of poliovirus as observed by electron microscopy of cultured cells. AB - Cells of differing culture types were inoculated with poliovirus at 37 C, sampled at intervals during the replicative cycle, and examined in thin sections by electron microscopy. The earliest samples, taken at 2 and 5 min postinoculation, showed virus particles adjacent to the exterior of the plasma membrane and others that had apparently penetrated it directly; later samples showed fewer such particles or none. Particles lying in the peripheral cytoplasm frequently appeared swollen and distorted in shape. No sign of virus entry by a pinocytotic process was found at any time. At 3 hr, and subsequently during the replication cycle, particles of progeny virus appeared in the cytoplasm. They were found free in the cytoplasmic matrix, aligned along the elements of filamentous complexes, and enclosed within vesicles. Some of the vesicles were found to be open to the extracellular space, indicating a likely mechanism of virus release. PMID- 4309885 TI - Genetic analysis with human--mouse somatic cell hybrids. PMID- 4309886 TI - Abortive transformation by the Tsa mutant of polyoma virus. PMID- 4309887 TI - Cerebral blood flow during sleep in patients with raised intracranial pressure. PMID- 4309888 TI - [Electron spin resonance spectrometer operating in the range of 112 MHz used in biological laboratories]. PMID- 4309889 TI - Cytochrome a3: destruction by light. AB - Spectroscopic measurements on cultures of Prototheca zopfii irradiated with blue light revealed that inhibition of respiration was accompanied by destruction of cytochrome a(3). One of the three b-type cytochromes and one of the two c-type cytochromes of this organism were also affected. Cytochrome oxidase of yeast (not resolved into the a and a(3) components) and cytochrome a(3) of beef-heart mitochondria were also destroyed by blue light. PMID- 4309890 TI - [Postsynaptic potentials in spinal motoneurons under rubro-spinal influences]. PMID- 4309891 TI - Renal autoregulation during infusion of noradrenaline, angiotensin and acetylcholine. PMID- 4309892 TI - Acute neuromuscular transmission failure in vas deferens after reserpine. PMID- 4309893 TI - Is noradrenaline an inhibitory transmitter to motoneurones? PMID- 4309894 TI - Control of spontaneous ventricular fibrillation during induced hypothermia in cats by acute cardiac sympathectomy. PMID- 4309895 TI - Role of peripheral chemoreceptors on adrenocortical secretory rates during hypoxia. PMID- 4309896 TI - Control of airborne dust produced by pneumatic jackpicks. II. PMID- 4309897 TI - A nationwide serum survey of Colombian military recruits, 1966. I. Description of sample and antibody patterns with arboviruses, polioviruses, respiratory viruses tetanus, and treponematosis. PMID- 4309898 TI - An outbreak of respiratory infection in children associated with rhinovirus types 16 and 29. PMID- 4309899 TI - Evidence for protective effect of an inactivated rhinovirus vaccine administered by the nasal route. PMID- 4309900 TI - Serologic evidence of arbovirus infections in wild ruminants. PMID- 4309901 TI - Total hepatic angiography and vascular dynamics in liver disease. PMID- 4309902 TI - Treatment of neoplasms of the liver. PMID- 4309903 TI - A role for glucagon in cardiac therapy. PMID- 4309904 TI - Stabilized neutral orthotolidine, SNORT, colorimetric method for chlorine. PMID- 4309905 TI - Partial purification and some properties of the factor in normal and leukaemic human urine stimulating mouse bone marrow colony growth in vitro. PMID- 4309906 TI - Variations in the ability of yeasts cultured in oxygen-controlled environments to oxidize NADH. PMID- 4309907 TI - Inhibition of mammalian uridinediphosphoglucose 4-epimerase by the dithiothreitol stimulated formation of NADH. PMID- 4309908 TI - Properties of the xanthine oxidase from human liver. PMID- 4309909 TI - Similar modifying effects of oligomycin and ATP on the K+-dependent p nitrophenylphosphatase activity of the (Na+ + K+)-activated ATPase. PMID- 4309910 TI - Reaction of the sulphydryl groups of lobster-muscle glyceraldehyde-3-phosphate dehydrogenase with organic mercurials. PMID- 4309911 TI - Kinetic studies of succinate dehydrogenase by electron paramagnetic resonance spectroscopy. PMID- 4309912 TI - Mechanism of the salicylate hydroxylase reaction. 3. Characterization and reactivity of chemically or photochemically reduced enzyme-flavin. PMID- 4309913 TI - Wilms' tumor and congenital aniridia. PMID- 4309914 TI - On the possible role of crystals in the origins of life. I. The adsorption of nucleosides, nucleotides and pyrophosphate by apatite crystals. PMID- 4309915 TI - Action of the Trenimon "Bayer" cytostatic on the morphological picture and some histochemical reactions of the intestinal mucosa of the rat. PMID- 4309916 TI - Hepatic amoebiasis; amoebic hepatitis and amoebic abscess with particular reference to connective tissues reaction and distribution of amoebae. PMID- 4309917 TI - Amoebiasis in an experimental model--some observations. PMID- 4309918 TI - Free radicals in pyrimidines: E.S.R. of gamma-irradiated single crystals of alloxantin. PMID- 4309919 TI - Isolation and identification of clostridia from North Sea sediments. PMID- 4309920 TI - Neomycin-containing media in the isolation of Clostridium botulinum and food poisoning strains of Clostridium welchii. PMID- 4309921 TI - Persistent rubella virus infection in hamster lung cells. PMID- 4309922 TI - Relationship between potentiation of H-1 growth by human adenovirus 12 and inhibition of the 'helper' adenovirus by H-1. PMID- 4309923 TI - Surface structure of vesicular stomatitis virus. PMID- 4309924 TI - Inherent photosensitivity of herpes virus and other enveloped viruses. PMID- 4309925 TI - Surveillance of paralytic poliomyelitis in the United States. 1966 and 1967 cases, and 1965-1967 cases associated with oral poliovirus vaccine. PMID- 4309927 TI - Hyponatremia in pituitary insufficiency. PMID- 4309926 TI - Studies on the lipids of sheep red blood cells. 3. The fayy acid composition of phospholipids in HK and LK cells. PMID- 4309929 TI - Occurrence and levels of 5-hydroxytryptamine in Schistosoma mansoni. PMID- 4309928 TI - Inhibition of trans-synaptically increased tyrosine hydroxylase activity by cycloheximide and actinomycin D. PMID- 4309930 TI - [Immunological aspects of multiple sclerosis]. PMID- 4309931 TI - Factors affecting the release of melanocyte-stimulating hormone in mammals. PMID- 4309932 TI - Loss of sleep. PMID- 4309933 TI - Immune responses to virus-induced tumours. PMID- 4309934 TI - [The fine structure of cornivore plague virus]. PMID- 4309935 TI - Histochemical studies on thiaminepyrophosphatase localization in the adult, embryonic and neoplastic liver cells using light and electron microscopy. PMID- 4309936 TI - Electron microscopic studies on the localization of guanosine-5'-triphosphatase A activity in cell nuclei. PMID- 4309937 TI - [Histological and histochemical studies on the mouth epithelium of the oam nest building Anabantidae]. PMID- 4309938 TI - [The PAS and Hale-PAS reactions in the adrenal medulla of white rats during cold stress]. PMID- 4309939 TI - Histochemical studies on the distribution of phosphatases in Trichomonas vaginalis. PMID- 4309940 TI - Antagonism between prostaglandin E2 and phenoxybenzamine on noradrenaline release from the cat spleen. PMID- 4309941 TI - Glucose 6-phosphatase: a multifunctional enzyme. PMID- 4309942 TI - Facial nerve tumors. PMID- 4309943 TI - The effect of various 3'5' cyclic nucleotides on gluconeogenesis and glycogenolysis in the perfused rat liver. PMID- 4309944 TI - After-care for alcoholics--a follow-up study. PMID- 4309945 TI - 32P-Distribution in oligonucleotides of rapidly sedimenting nucleolar RNA's of hepatomas and normal rat liver. PMID- 4309946 TI - Inhibition of spontaneous breast tumors in a high MTV strain. PMID- 4309948 TI - Search for herpes simplex, mumps and lymphocytic choriomeningitis associated with central nervous system disease at Vellore, Southern India. PMID- 4309947 TI - Study of antiviral activity of tender leaves of Margosa tree (Melia azadericta) on vaccinia and variola virus: a preliminary report. PMID- 4309949 TI - Problems in haemagglutination test with faecal viruses. PMID- 4309950 TI - Traveling-wave velocity in the human cochlea. PMID- 4309951 TI - Time-domain measurements of cochlear nonlinearities using combination click stimuli. PMID- 4309953 TI - The association of cholesterol, 5'-nucleotidase, and alkaline phosphodiesterase I with a distinct group of microsomal particles. PMID- 4309952 TI - Lipids of Acanthamoeba castellanii. Composition and effects of phagocytosis on incorporation of radioactive precursors. AB - The lipids of Acanthamoeba castellanii (Neff) consist of 52% neutral lipids and 48% polar lipids. Triglycerides account for 75% and free sterols for 17% of the neutral lipids. The major phospholipids are phosphatidylcholine (45%), phosphatidylethanolamine (33%), phosphatidylserine (10%), a phosphoinositide (6%), and diphosphatidylglycerol (4%). The phosphoinositide is unique in that it contains fatty acids, aldehyde, inositol, and phosphate in the ratio of 1.4:0.5:1.1, but it contains no glycerol. Sphingomyelin, cerebrosides, psychosine, and glycoglycerides were not detected, but small amounts of unidentified long chain bases and sugars are present. The rates of uptake of palmitate-1-(14)C and of its incorporation into glycerides and phospholipids were not affected by the phagocytosis of polystyrene latex beads. Although phagocytosis usually decreased the uptake by amebas of phosphate-(32)P, serine-U (14)C, and inositol-2-(3)H, their subsequent incroporation into phospholipids was not demonstrably stimulated or inhibited by phagocytosis. Phagocytosis did seem to increase the incorporation into ameba phospholipids of phosphatidylcholine-1 ,2-(14)C but not that of phosphatidylethanolamine-1 ,2-(14)C. These experiments, in which the incorporation of radioactive precursors into total cell lipids was measured, do not, of course, eliminate the possibility that localized effects may occur. PMID- 4309954 TI - Phagocytosis of latex beads by Acahamoeba castellanii (Neff). 3. Isolation of the phagocytic vesicles and their membranes. AB - A method is described for the rapid and efficient isolation of phagocytic vesicles from large scale cultures of Acanthamoeba castellanii (Neff) that have been incubated with polystyrene latex beads. Cells were allowed to phagocytose latex beads for 30 min and then were homogenized, and the phagocytic vesicles were isolated by one centrifugation through several layers of sucrose. Identity and purity of the phagocytic vesicles were determined by electron microscopy, chemical analyses, and assays of acid phosphatase, alpha- and beta-glucosidase, and reduced nicotinamide adenine dinucleotide dehydrogenase. When phagocytosis was allowed to occur for longer periods the phagocytic vesicles appeared to fuse with each other and perhaps with digestive vacuoles. The resultant vesicles which contained many beads were heavier than those which consisted of only one bead or a few beads with a closely applied membrane. Ultrasonication ruptured the isolated vesicles, and the membranes could then be isolated in 30-50% yield based on phospholipid analysis. These membranes were essentially free of acid hydrolases and, presumably, other soluble proteins, as was also indicated by their low ratio of protein to phospholipid. The membranes have been prepared both as closed vesicles and as open sheets. PMID- 4309955 TI - Collagenases in human synovial fluid. AB - An enzyme which degrades native collagen at neutral pH has been isolated from cultures of rheumatoid synovium in vitro, but little or no collagenolytic activity has been found in homogenates of fresh rheumatoid synovium. Similar to most other mammalian collagenases this synovial enzyme is readily inhibited by serum proteins. Proteins of synovial fluid are derived largely from serum and synovial fluid from noninflamed joints was found to inhibit synovial collagenase; the inhibitor was destroyed by trypsin, but not by hyaluronidase. Inhibitory activity was reduced in approximately one-half of the fluids from patients with rheumatoid arthritis. In a total of nine synovial fluids, collagenolytic activity was detectable. This activity was not present in constant amounts in synovial fluids aspirated at different times from the same patient and tended to vary inversely with the titer of inhibitory proteins. The collagenolytic activity in the synovial fluids from different patients was variably inhibited by serum proteins. Two distinct collagenases were detected in some rheumatoid synovial fluids and separated by gel filtration. One, labeled "B" enzyme, with an estimated molecular weight 20,000-25,000 resembled the collagenase obtained from synovial cultures. The other, labeled "A" enzyme degraded collagen fibrils as well as collagen in solution. Disc electrophoresis on acrylamide gels and electron microscopy of segment long spacing (SLS) aggregates of reaction products of the enzymes at 27 degrees C demonstrated that both "A" and "B" enzymes cleaved collagen molecules at a point three-quarters from the amino terminal end of the molecule. Thus collagen degradation in rheumatoid arthritis could result from the operation of these two collagenases. PMID- 4309956 TI - Lipid metabolism in human platelets. II. De novo phospholipid synthesis and the effect of thrombin on the pattern of synthesis. AB - Washed human platelets were incubated with radioactive glycerol; the platelets were able to synthesize de novo the major phosphoglycerides including phosphatidic acid, phosphatidylinositol, phosphatidyl choline, phosphatidyl ethanolamine, and phosphatidyl serine. The specific activities of the phosphoglycerides obtained after glycerol incorporation indicate that phosphatidic acid, phosphatidylinositol, and phosphatidyl choline are metabolically active relative to phosphatidyl ethanolamine and that formation of phosphatidyl serine occurs to a much more limited extent. When platelets were incubated with bovine thrombin, 1 U/ml, the pattern of glycerol incorporation into phospholipid was changed. There was a 3-fold decrease in the total incorporation into lipid in 30 min with a relative 5-fold decreased incorporation into phosphatidyl choline and phosphatidyl ethanolamine and a 5-fold increased incorporation into phosphatidyl serine. The increased incorporation into phosphatidyl serine. The increased incorporation into phosphatidyl serine was maximal within the first 2 min but was transient, since within 20 minutes, the rate returned to that seen in platelets incubated with glycerol alone. Purified human thrombin also produced this same effect on phospholipid synthesis in platelets. Trypsin produced effects on phosphoglyceride formation similar to those seen with thrombin, and the trypsin-induced effect was inhibited by prior incubation of trypsin with soybean trypsin inhibitor, suggesting that proteolysis may be required for the observed effects on phospholipid synthesis. PMID- 4309957 TI - The effect of valinomycin on the toad bladder: antagonism to vasopressin and aldosterone. PMID- 4309958 TI - The distribution and concentration of 75Se-selenomethionine in man. PMID- 4309960 TI - Vitamin D3 metabolism in renal osteodystrophy. PMID- 4309961 TI - Femoral neuropathy secondary to retroperitoneal hemorrhage. PMID- 4309959 TI - Release to the cerebral ventricles of substances with possible transmitter function in the caudate nucleus. AB - 1. One caudate nucleus of the anaesthetized cat was superfused by perfusing the anterior horn of one lateral cerebral ventricle. The perfusates were examined for their content in acetylcholine (ACh), dopamine, homovanillic acid (HVA) and 5 hydroxytryptamine (5-HT), at rest and after a variety of stimuli.2. When prostigmine was added to the perfusion fluid, ACh appeared in the effluent; its concentration tended to rise in the course of an experiment. Various afferent stimuli, all of which caused evoked responses recorded from the contra-lateral caudate nucleus, increased the ACh content of the effluent. Effective stimuli were noise and electrical stimulation of afferent nerves or of certain regions of the brain including the ipsi-lateral substantia nigra.3. The dopamine content of the effluent was extremely low (of the order of 50 pg/min) at rest, but, on occasion, rose sharply when the substantia nigra was stimulated electrically with trains of pulses repeated once every 3 sec. The results were inconsistent.4. Since dopamine in tissue is rapidly transformed enzymically into HVA, the appearance of this acid in the perfusate was examined.5. At rest, HVA was found to appear in the effluent at a rate of 2-8 ng/min. Its concentration was rapidly depressed by increasing the depth of anaesthesia.6. Stimulation of the substantia nigra for periods of 3 or 4 min caused an increment in the HVA content of the effluent lasting 1 hr or more. It was frequently seen when two points of the substantia nigra were stimulated simultaneously, less regularly with only one stimulating electrode, and rarely if this was placed in the most caudal part of the substantia nigra.7. These results strongly support the view that there is a dopaminergic nigro-striatal pathway. The following assumption would explain the erratic appearance of dopamine and the long duration of increments in HVA: many of the axons originating in the substantia nigra end either in the putamen or in parts of the caudate nucleus which are far away from the ventricular surface; any dopamine released from these axons will not reach the ventricular surface at all, and HVA will, at best, reach it very slowly.8. Small amounts of 5-HT appeared in the ventricular perfusate, and the quantity rose after the administration of monoamine oxidase inhibitors. It was not increased by the type of stimuli used in this work to elicit the release of ACh or HVA. PMID- 4309962 TI - Mucinous urachal adenocarcinoma. A case report and a review of the literature. PMID- 4309964 TI - Hepatic source of plasma amino acids. PMID- 4309963 TI - Current concepts. Vitamin D. PMID- 4309965 TI - Web-foot or syndactylism in the fowl. PMID- 4309966 TI - Perceptual aspects of psychopathology. PMID- 4309967 TI - Schizophrenia: evidence of a pathologic immune mechanism. PMID- 4309968 TI - Electron paramagnetic resonance study of x-ray and gamma-ray irradiated peptides in the solid state. PMID- 4309969 TI - The value of selective angiography in the diagnosis of tumors in pancreas and liver. PMID- 4309970 TI - Differentiation of intrahepatic and extraheptic masses by arteriography. PMID- 4309971 TI - Effect of liver cell fragments on Entamoeba histolytica in monobacterial cultures. PMID- 4309972 TI - A surface-active lysosome in Entamoeba histolytica. PMID- 4309973 TI - Studies on the urinary excretion, biological effects and origin of oestrogens in post-menopausal women. PMID- 4309974 TI - A subcellular agent inducing plasma cell leukemias in mice. The relation of this agent to amyloidosis and chronic murine pneumonia. PMID- 4309975 TI - Studies on syndrome of diabetes insipidus associated with oligosyndactyly in mice. PMID- 4309976 TI - Angiotensin-protective cofactor. PMID- 4309977 TI - Regulation of riboflavin-metabolizing enzymes in riboflavin deficiency. PMID- 4309978 TI - In vivo perfusion of proximal tubules of the rat: glomerulotubular balance. PMID- 4309979 TI - Effects of fasting and diabetes on fatty acid synthesis by heart mitochondria. PMID- 4309980 TI - [Non-cancerous mastopathies]. PMID- 4309981 TI - Effects of streptozotocin in a patient with islet cell carcinoma. PMID- 4309982 TI - Critical evaluation of specificity in electron microscopical radioautography in animal tissues. PMID- 4309983 TI - Enzymic activities during the transformation of crypt to columnar intestinal cells. PMID- 4309984 TI - Response of somatic cell hybrids to exposure to adenovirus type 2 and 12. PMID- 4309985 TI - Studies on induced cellular autophagy. II. Characterization of the membranes bordering autophagosomes in parenchymal liver cells. PMID- 4309986 TI - The composition and structure of the carbohydrate of pineapple stem bromelain. PMID- 4309987 TI - The isolation and structure identification of uridine 5-(2-acetamido-2-deoxy alpha-D-glucopyranosyluronic acid pyrophosphate) from Micrococcus lysodeikticus cells. PMID- 4309988 TI - Characterization of a phosphatase specific for phosphorylated histones and protamine. PMID- 4309989 TI - Assembly of the mitochondrial membrane system. I. Characterization of some enzymes of the inner membrane of yeast mitochondria. PMID- 4309990 TI - The behavior of horse liver alcohol dehydrogenase in guanidine hydrochloride solutions. PMID- 4309991 TI - Inhibition of glucagon effects in perfused rat liver by (+)decanoylcarnitine. PMID- 4309992 TI - [Studies on bacterial and viral flora of resected tonsils]. PMID- 4309993 TI - Observations on synovial sarcoma in Indians. PMID- 4309994 TI - Mouse cytomegalovirus: placental infection. PMID- 4309995 TI - Murine leukemialike virus and the immunopathologic disorders of New Zealand black mice. PMID- 4309996 TI - Effects of procaine, pentobarbital and halothane on synaptic transmission in the central nervous system. PMID- 4309997 TI - A comparison of the sensitivity to chemical stimuli of adrenergic and cholinergic neurons in the cat stellate ganglion. PMID- 4309998 TI - Trans-synaptic induction of adrenal tyrosine hydroxylase. PMID- 4309999 TI - Dissociation of the increased formation of cardiac adenosine 3',5'-monophosphate from the positive inotropic effect of norepinephrine. PMID- 4310000 TI - The cardiovascular effects of cranial artery infusions of acetylcholine in the dog and their relevance to the angiotensin response. PMID- 4310001 TI - Dose-dependent, biphasic effects of angiotensin on fluid transfer by rat colon. PMID- 4310002 TI - Identification of adenosine triphosphate in human plasma and the concentration in the venous effluent of forearm muscles before, during and after sustained contractions. AB - 1. When diluted human plasma is perfused through a frog heart, a marked augmentation of the heartbeat is produced which is very similar in action to that of low concentrations of adenosine triphosphate (ATP) on the heart.2. It was established that the substance in the plasma responsible for the heart stimulation was ATP. The following tests were used: (a) the diluted plasma emitted light from firefly lantern extract characteristic of the light signal produced by a solution of ATP; (b) the stimulatory effect on the frog heart and luminescent effect upon the firefly extract were abolished by incubation of the plasma solution with the enzyme apyrase, which converts ATP to adenosine monophosphate (AMP); AMP does not stimulate the heart or cause light to be emitted from firefly extract; (c) the stimulatory substance in the plasma was eluted through a column of Sephadex G-25 in the same pattern as ATP; and (d) simultaneous assay of plasma solutions on frog heart and firefly extract produced the same quantitative result as that produced by a solution of ATP.3. The amount of ATP in plasma from the venous blood of resting subjects ranged from 0.19 to 0.95 mug/ml. (mean 0.63 mug/ml., S.D. +/- 0.25); up to half of the ATP detected could be attributed to blood platelet damage. Simultaneous arterial and venous samples of blood from four subjects at rest had mean concentrations of 0.19 mug/ml. (0.07-0.26 mug/ml.) and 0.70 mug/ml. (0.57-0.84 mug/ml.) respectively.4. The concentration of ATP in the venous effluent from exercising forearm muscles was measured. The venous concentration consistently increased over the resting values in response to exercise while in one subject little change occurred in the arterial blood concentration during the exercise. It was concluded that the ATP was added to the blood in its passage through the muscle bed.5. The origin of the ATP, including erythrocytes, blood platelets and active skeletal muscle, is discussed. PMID- 4310004 TI - An automatic 2+2 dose assay using the rat blood pressure. PMID- 4310003 TI - Vascular resistance in the perfused isolated rat tail. PMID- 4310005 TI - Further evidence that acetylcholine is not a transmitter at chemoreceptors. PMID- 4310006 TI - [Electromyography in neurogenic and pseudoneurogenic disorders of eye movement. V. Synkinetic movements]. PMID- 4310007 TI - [Sellar and suprasellar tumors]. PMID- 4310008 TI - [Studies of the early diagnosis of diabetic microangiopathies, using the skin clearance test with RISAH]. PMID- 4310010 TI - [Epitheliomas and cutaneous melanoblastoma]. PMID- 4310009 TI - [Malignant tumors of the uterus: uterine cervix and body]. PMID- 4310011 TI - [Phenylketonuria. 3. Evaluation of early treatment]. PMID- 4310012 TI - [Evaluation of adreno-cortical activity in the newborn]. PMID- 4310013 TI - [Analysis of 45 cases of cancer of the gallbladder]. PMID- 4310014 TI - The influence of transplantable Crocker sarcoma on growth of transplantable chrysoidin hepatoma in mice. PMID- 4310015 TI - High frequency electro-shock seizures and their antagonism in developing mice. 3. Effects of cortisol, corticosterone, deoxycorticosterone, dexamethasone and a synthetic corticotropine. PMID- 4310016 TI - [Abrikosoff's tumor]. PMID- 4310017 TI - Adenyl cyclase and phosphodiesterase activities in brain areas of man, monkey and rat. PMID- 4310018 TI - Hyperreactio luteinalis: postpartum persistence. PMID- 4310019 TI - Viral isolations from bovine eye tumors. PMID- 4310021 TI - Malignant mixed tumors of salivary gland origin. PMID- 4310020 TI - Comparative study of the effect of three antibiotics on renal function. AB - 1. Therapeutic doses of colistin sulphomethate sodium B.P. (Colomycin), pento-N sulphomethylpolymyxin B sodium (Thiosporin) and ampicillin B.P. (Penbritin) as well as normal saline have been given to volunteers with normal kidney function.2. A blind crossover technique was used and the effects of the compounds on blood levels and clearances of urea and creatinine studied.3. All four treatments resulted in some changes in the parameters measured but were reversible. The most marked changes were found with pento-N sulphomethylpolymyxin B sodium and were also associated with severe side-effects.4. In contrast to penicillins it is established that the process of tubular secretion sensitive to probenecid block plays no part in the renal excretion of polymyxins. PMID- 4310022 TI - Defective photochemical repair in epithelium predisposed to field cancerization. PMID- 4310023 TI - Detection of a small virus in a cultivated human Wilms' tumor. PMID- 4310024 TI - Effect of hypocalcemia and vitamin D-induced hypercalcemia on the incidence of metastases in rats. PMID- 4310025 TI - Aldolase isozymes in human tissue and serum. With special reference to cancer diagnosis. PMID- 4310026 TI - [The problem of the so-called transplant lung]. PMID- 4310027 TI - [Congenital adrenogenital salt-losing syndrome with development of a prostate gland in a female infant]. PMID- 4310028 TI - [Enzyme histochemistry of solid and tubular basal cell adenomas of the salivary glands]. PMID- 4310029 TI - Assessment of a test of adrenocortical function using beta1-25 corticotrophin. PMID- 4310030 TI - Synthesis of corticotrophin-like polypeptides and protein by bovine hypothalamus, median eminence and pituitary tissue slices. PMID- 4310031 TI - Autoradiographic studies of uridine-5-H3 uptake in Entamoeba histolytica in the CLG medium. PMID- 4310032 TI - Lysosomal hydrolases in Acanthamoeba sp. PMID- 4310033 TI - [Neurogenic tumors of the oral cavity. Clinical case report]. PMID- 4310034 TI - Longitudinal banded pigmentation of nails following adrenalectomy for cushing's syndrome. PMID- 4310035 TI - Childhood cancer and congenital defects. A study of U.S. death certificates during the period 1960-1966. PMID- 4310036 TI - The replete pediatrician and the etiology of lower respiratory tract infections. Presidential address to the Society for Pediatric Research. PMID- 4310037 TI - [The use of modified stimulation test in the diagnosis of adrenal cortex diseases]. PMID- 4310038 TI - [Effect of the synthetic corticotropin on the weight and morphologic picture of adrenal glands of the rat]. PMID- 4310039 TI - [Diabetic polyneuropathy in the light of our cases]. PMID- 4310040 TI - [Study on the classification of common viral encephalitides]. PMID- 4310041 TI - [Action of thymic extracts (B and II B) on the development of Ehrlich's ascites carcinoma. (Biological and biochemical aspects)]. PMID- 4310042 TI - [Morphological and biochemical changes in the lung of the white mouse vaccinated with type 5 adenovirus. I. Morphological lesions]. PMID- 4310043 TI - [Specific resistance to tumors of viral etiology. 1. Resistance to tumors induced by various oncogenic viruses, and certain characteristic traits of this phenomenon]. PMID- 4310044 TI - [The molecular organization of biological membranes]. PMID- 4310045 TI - [Biochemical bases of light reception]. PMID- 4310046 TI - [A study of comparative effectiveness of polymyxin M and monomycin in the treatment of children with intestinal coli infection]. PMID- 4310047 TI - [The effect of videin D3 therapy of children with rickets]. PMID- 4310048 TI - [Paradoxical sleep]. PMID- 4310049 TI - Biochemical patterns in brain tumours. II. Enzymes of the tricarboxylic acid cycle. PMID- 4310050 TI - Formation of extracellular adenosine triphosphate by human erythrocytes. PMID- 4310051 TI - Effects of radiation damage to bone marrow on susceptibility of chicks to erythroleukemia virus. PMID- 4310052 TI - Replication of oncogenic viruses in virus-induced tumor cells-their persistence and interaction with other viruses. PMID- 4310053 TI - Methylation of herpes-simplex-virus deoxyribonucleic acid. PMID- 4310054 TI - The delayed neurotoxic effect of some organophosphorus compounds. Identification of the phosphorylation site as an esterase. AB - 1. Organophosphorus compounds that produce a delayed neurotoxic effect in hens phosphorylate a specific site in the brain soon after administration. 2. Phosphorylation of the specific site by di-isopropyl [(32)P]phosphorofluoridate in vitro is blocked by the prior addition of phenyl phenylacetate. 3. A small proportion of the total activity of hen brain hydrolysing phenyl phenylacetate in vitro was shown to be due to an enzyme different from two others previously described. 4. This enzyme is only slightly inhibited in vitro by concentrations of tetraethyl pyrophosphate and paraoxon (diethyl 4-nitrophenyl phosphate) up to 64mum and is completely inhibited by 6mum-di-isopropyl phosphorofluoridate and 128mum-mipafox. 5. It is also inhibited in vivo by effective doses of neurotoxic organophosphorus compounds but not by high doses of non-neurotoxic analogues. 6. It is deduced that the active site of this enzyme is the phosphorylation site associated with the genesis of delayed neurotoxicity. PMID- 4310055 TI - "Rapidly appearing" molybdenum electron-paramagnetic-resonance signals from reduced xanthine oxidase. AB - Further electron-paramagnetic-resonance studies relating to the role of molybdenum in the enzymic mechanisms of xanthine oxidase were carried out. The classification of the various molybdenum signals obtained on reducing the enzyme is briefly discussed. The group of ;Rapidly appearing' signals, which are obtained with all substrates within the turnover time and which show interaction with exchangeable protons, were studied in detail. Signals with salicylaldehyde, purine and xanthine in H(2)O and in 95% D(2)O were examined at 9 and 35GHz and interpreted with the help of computer simulation. Molybdenum atoms in a number of different chemical environments are involved, each substrate giving rise to two superimposed spectra with slightly different parameters; g values and proton splittings were determined. The spectrum with salicylaldehyde is believed to represent the reduced enzyme alone not in the form of a complex with substrate and its two constituents are believed to represent the two molybdenum atoms bonded slightly differently within the enzyme molecule. With purine and xanthine the spectra are thought to represent complexes of reduced enzyme with substrate molecules. With xanthine one signal-giving species shows coupling to two equivalent protons, whereas in all the other species observed two non-equivalent protons are involved. The origin of the protons is discussed in the light of the direct hydrogen-transfer mechanism implicated earlier for the enzyme. It is concluded that the proton derived from the substrate is located at least 3a from the molybdenum atom with which it interacts. PMID- 4310056 TI - Complex-formation between reduced xanthine oxidase and purine substrates demonstrated by electron paramagnetic resonance. AB - The origin of the Rapid molybdenum electron-paramagnetic-resonance signals, which are obtained on reducing xanthine oxidase with purine or with xanthine, and whose parameters were measured by Bray & Vanngard (1969), was studied. It is concluded that these signals represent complexes of reduced enzyme with substrate molecules. Xanthine forms one complex at high concentrations and a different one at low concentrations. Purine forms a complex indistinguishable from the low concentration xanthine complex. There are indications that some other substrates also form complexes, but uric acid, a reaction product, does not appear to do so. The possible significance of the complexes in the catalytic cycle of the enzyme is discussed and it is suggested that they represent substrate molecules bound at the reduced active site, waiting their turn to react there, when the enzyme has been reoxidized. Support for this role for the complexes was deduced from experiments in which frozen samples of enzyme-xanthine mixtures, prepared by the rapid-freezing method, were warmed until the signals began to change. Under these conditions an increase in amplitude of the Very Rapid signal took place. Data bearing on the origin of the Slow molybdenum signal are also discussed. This signal disappears only slowly in the presence of oxygen, and its appearance rate is unaffected by change in the concentration of dithionite. It is concluded that, like other signals from the enzyme, it is due to Mo(v) but that a slow change of ligand takes place before it is seen. The Slow species, like the Rapid, seems capable of forming complexes with purines. PMID- 4310057 TI - The distribution of vitamin D3 metabolites in human serum and tissues. PMID- 4310058 TI - The metabolism of 4-hydroxypyridine by Agrobacterium sp.: a new ring cleavage of the pyridine nucleus. PMID- 4310059 TI - Studies in vitro on the effects of 1H,2H,4H(5H)-octafluorocyclohexane and 1H,4H(2H)-nonafluorocyclohexane on enzymes and organelles. AB - A comparison has been made of the effect of 1H,2H,4H(5H)-octafluorocyclohexane, which is highly toxic (LD(50) 17mg./kg. in rats), and of 1H,4H(2H) nonafluorocyclohexane, which is relatively non-toxic (LD(50)>440mg./kg. in rats), on the respiration of rat liver homogenates and mitochondria in vitro. 1H,2H,4H(5H)-Octafluorocyclohexane strongly inhibited the respiration of both homogenates and mitochondria, but neither compound had any significant effect on glycolysis or on glutamate dehydrogenase or NADH-cytochrome c reductase activity. 1H,2H,4H(5H)-Octafluorocyclohexane, however, caused a very marked inhibition of cytochrome oxidase activity, causing an almost complete lesion in this region of the respiratory chain. 1H,4H(2H)-Nonafluorocyclohexane was without effect in this respect. A marked decrease in turbidity of mitochondrial suspensions at 520nm. was caused by addition of both compounds, the effect being greater with 1H,2H,4H(5H)-octafluorocyclohexane. ATP, Mg(2+) and bovine serum albumin did not reverse these changes. Mitochondrial adenosine triphosphatase activity was increased twofold by the toxic compound, but only slightly by the non-toxic compound. Electron-microscopic examination of mitochondria treated with 1H,2H,4H(5H)-octafluorocyclohexane revealed gross morphological damage, whereas the effect of 1H,4H(2H)-nonafluorocyclohexane appeared to be merely to cause swelling. The results obtained account, to some extent at any rate, for the toxic effects of 1H,2H,4H(5H)-octafluorocyclohexane. PMID- 4310060 TI - Multiple light-induced reactions of cytochromes b and c in Rhodopseudomonas spheroides. AB - Illumination of chromatophore preparations from Rhodopseudomonas spheroides causes the oxidation of a cytochrome c and a slight oxidation of a cytochrome b with a maximum at 560nm. When illuminated in the presence of antimycin A the oxidation of cytochrome c was more pronounced and cytochrome b(560) was reduced; the dark oxidation of cytochrome b(560) was biphasic in the presence of succinate, but not in the presence of NADH, a less effective reductant. Split beam spectroscopy showed that, in addition to the reduction of cytochrome b(560), another pigment with maxima at 565 and 537nm. was reduced and was more rapidly oxidized in the dark than cytochrome b(560). This pigment, tentatively identified as cytochrome b(565), was also detected in spectra at 77 degrees k, after brief illumination at room temperature; the maxima at 77 degrees k were at 562 and 536nm. In the absence of antimycin A, light caused a transient reduction of cytochrome b(565) and an oxidation of cytochrome b(560). Dark oxidation of b(565) was rapid, even in the presence of antimycin A and succinate. Difference spectra, at 77 degrees k, of ascorbate-reduced minus succinate-reduced chromatophores or of anaerobic succinate-reduced minus aerobic succinate-reduced chromatophores suggested that two cytochromes c were present, with maxima at 547 and 549nm. When chromatophores frozen at 77 degrees k were illuminated both these cytochromes c were oxidized, indicating a close association with the photochemical reaction centre. A scheme involving two reaction centres is proposed to explain these results. PMID- 4310061 TI - The importance of alpha-glycerophosphate oxidase in oxidation of extramitochondrial reduced nicotinamide-adenine dinucleotide in vertebrate and insect muscle. PMID- 4310062 TI - The effects of calcium ions on the activites of hexokinase, phosphofructokinase and fructose 1,6-diphosphatase from vertebrate and insect muscles. PMID- 4310063 TI - [Some electrographic characteristics of sleep in schizophrenic patient]. PMID- 4310064 TI - Meningeal tumors induced in calves with the bovine cutaneous papilloma virus. PMID- 4310065 TI - Primary tumors in the CNS of carnivores. PMID- 4310066 TI - [Pituitary-adrenal reserve after prolonged treatment with dexamethasone in some skin diseases]. PMID- 4310067 TI - [Regularities in the changes of activity of several rat liver enzymes after total single-dose irradiation (histoenzymologic research)]. PMID- 4310068 TI - [Activity changes of several oxidation-reduction enzymes in plants with various radiosensitivity]. PMID- 4310069 TI - [Effect of radiation on the process of secretion of adrenocorticotropic hormone (ACTH) from the anterior lobe of the hypophysis into the blood]. PMID- 4310070 TI - [Solitary hepatoma in the process of cancerisation. Rules for hepatectomy]. PMID- 4310071 TI - [Contribution of histoenzymological technics to the study of congenital hypotonias]. PMID- 4310072 TI - [Clinical or infraclinical peripheral neuropathies and latent diabetes; angiopathic aspects]. PMID- 4310073 TI - [Klinefelter's syndrome with mosaicism XY-XXY-XXYY]. PMID- 4310074 TI - Organ-culture propagation of infectious canine hepatitis virus. PMID- 4310075 TI - Armour-Baldwin tools up for stockpiling of clostridium perfringens antitoxin to meet emergency needs. PMID- 4310076 TI - [Comparison of diagnostic usefulness of determinations of N-acetyl-beta-D glucosaminase in epidemic hepatitis with other enzymatic tests (SGOT, SGPT, NADP)]. PMID- 4310077 TI - [Pharmacodynamic aspects of associations of hypertension with other medicinal factors]. PMID- 4310078 TI - Immunochemistry of a formamide-extracted antigen from Clostridium perfringens cell walls. AB - The type-specific antigen of a strain of Clostridium perfringens involved in food poisoning was isolated from the cell wall by the use of hot formamide. The antigen appears to consist of polysaccharide or mucopeptide. The formamide extract was shown to be heterogeneous by gel filtration on Sephadex G-200. The serologically active fraction contained about 25% of the amount of protein present in the original formamide extract. Hexosamine, acetyl groups, and carbohydrate also were detected. The formamide extract showed a high degree of serological activity. The serological activity was increased twofold on Sephadex gel filtration. PMID- 4310079 TI - Specificity and evolutionary divergence of the antigenic structure of the polypeptide chain elongation factors. AB - Antisera have been prepared against two electrophoretically homogeneous "polypeptide chain elongation factors," T and G, from Escherichia coli. Inactivation and precipitation tests showed that these two fractions were antigenically distinct with no cross-reaction. The immune inactivation curve of G factor from E. coli was distinguishable from that of G factor from Pseudomonas fluorescens. Mammalian factors were not inhibited by antibody directed against the E. coli T and G factors. By Ouchterlony diffusion tests, the antisera also detected significant antigenic variability among different bacterial species. It is concluded that the factors have undergone considerable evolutionary divergence in their antigenic structure. PMID- 4310080 TI - Mechanism of action of the antifungal antibiotic pyrrolnitrin. AB - Pyrrolnitrin at 10 mug/ml inhibited the growth of Saccharomyces cerevisiae, Penicillium atrovenetum, and P. oxalicum. The primary site of action of pyrrolnitrin on S. cerevisiae was the terminal electron transport system between succinate or reduced nicotinamide adenine dinucleotide (NADH) and coenzyme Q. At growth inhibitory concentrations, pyrrolnitrin inhibited endogenous and exogenous respiration immediately after its addition to the system. In mitochondrial preparations, the antibiotic inhibited succinate oxidase, NADH oxidase, succinate cytochrome c reductase, NADH-cytochrome c reductase, and succinate-coenzyme Q(6) reductase. In addition, pyrrolnitrin inhibited the antimycin-insensitive reduction of dichlorophenolindophenol and of the tetrazolium dye 2,2'-di-p nitrophenyl-(3,3'-dimethoxy-4,4'-bi-phenylene)5,5'-diphenylditetrazolium. The reduction of another tetrazolium dye, 2-p-iodophenyl-3-p-nitrophenyl-5 phenyltetrazolium chloride, that was antimycin-sensitive, was also inhibited by pyrrolnitrin. The antibiotic had no effect on the activity of cytochrome oxidase, and it did not appear to bind with flavine adenine dinucleotide, the coenzyme of succinic dehydrogenase. In whole cells of S. cerevisiae, pyrrolnitrin inhibited the incorporation of (14)C-glucose into nucleic acids and proteins. It also inhibited the incorporation of (14)C-uracil, (3)H-thymidine, and (14)C-amino acids into ribonucleic acid, deoxyribonucleic acid, and protein, respectively. The in vitro protein synthesis in Rhizoctonia solani and Escherichia coli was not affected by pyrrolnitrin. Pyrrolnitrin also inhibited the uptake of radioactive tracers, but there was no general damage to the cell membranes that would result in an increased leakage of cell metabolites. Apparently, pyrrolnitrin inhibits fungal growth by inhibiting the respiratory electron transport system. PMID- 4310081 TI - Multiple forms of lactate dehydrogenase in Staphylococcus aureus. AB - Activities for nicotinamide adenine dinucleotide (NAD)-dependent and NAD independent forms of lactate dehydrogenase (LDH) were measured in cell-free extracts of Staphylococcus aureus strain PS 6 for the d and l isomers of lactate. Data obtained for the NAD-dependent lactate dehydrogenases indicate that oxidation of both isomers of lactate is due to both an l-lactate-specific LDH and a lactate racemase. After acrylamide gel electrophoresis, two bands exhibiting LDH activity were detected in crude or in partially purified cell-free extracts. The fast band exhibited LDH activity that was not NAD-dependent for both isomers of lactate, whereas, the slow band had very high NAD-dependent LDH activity for the l isomer but just detectable activity or the d isomer. Both bands appeared when d-lactate was used as the substrate, but only the slow band was formed when l-lactate was the substrate. NAD-dependent LDH, in apparent association with a nonspecific tetrazolium-reducing protein, is responsible for the production of the slow band. PMID- 4310082 TI - Violagabriellae variant of Staphylococcus epidermidis on normal human skin. AB - Twenty-seven strains of a reddish violet pigment-producing variety of Staphylococcus epidermidis have been recovered from normal human skin. They closely resemble the previously unique Castellani strain, named Micrococcus violagabriellae, which was placed by K. J. Steel in S. epidermidis. These strains are classified as S. epidermidis by using the Baird-Parker schema; however, besides the pigment produced, they also differ from S. epidermidis in proteolytic activity and effect on litmus milk. The variety seems to be part of the normal flora of the human axilla. PMID- 4310083 TI - Ileal loop fluid accumulation and production of diarrhea in rabbits by cell-free products of Clostridium perfringens. AB - The ability of cell extracts and culture filtrates of various strains of C. perfringens to produce ileal loop fluid accumulation and overt diarrhea in rabbits was tested. Good correlation was obtained in the ability of whole cells and a toxic factor (present in cell extracts and concentrated culture filtrates) to produce both fluid accumulation in ileal loops and diarrhea when injected into the normal ileum of the rabbit. The toxic factor was present in cell-free preparations when cells were grown in a sporulation medium, but not when they were grown in an asporogenic medium. The factor was shown to be heat labile, nondialyzable, and was inactivated by Pronase but not by trypsin, lipase, or amylase. Loss of activity occurred at pH 1.0, 3.0, 5.0, and 12.0. PMID- 4310084 TI - The effects of glucagon, dibutyryl cyclic adenosine 3',5'-monophosphate, and concentration of free fatty acid on hepatic lipid metabolism. PMID- 4310085 TI - Hormonal regulation of transfer ribonucleic acid and transfer ribonucleic acid methylating enzymes during development of the mouse mammary gland. PMID- 4310086 TI - Insulin-receptor interaction in isolated fat cells. I. The insulin-like properties of p-chloromercuribenzene sulfonic acid. PMID- 4310087 TI - Effect of thyroid-stimulating hormone and prostaglandins on thyroid adenyl cyclase activation and cyclic adenosine 3',5',-monophosphate. PMID- 4310088 TI - An extracellular nuclease from Serratia marcescens. II. Specificity of the enzyme. PMID- 4310089 TI - Purification and properties of lactaldehyde dehydrogenase from Escherichia coli. PMID- 4310090 TI - Kinetics of malic-lactic transhydrogenase. Abortive complex formation with substrates and products. PMID- 4310091 TI - Synthesis of carbamyl phosphate synthetase in amphibian liver in vitro. The effect of thyroxine. PMID- 4310092 TI - Reconstitution of succinate-coenzyme Q reductase (complex II) and succinate oxidase activities by a highly purified, reactivated succinate dehydrogenase. PMID- 4310093 TI - Inhibition of horse liver alcohol dehydrogenase by L-3,3',5-triiodothyronine. PMID- 4310094 TI - [Column and paper chromatographic demonstration of an acid and phosphatase stable phosphorus compound in plants]. PMID- 4310095 TI - Transplantable hepatomas induced in strain-2 guinea pigs by diethylnitrosamine: characterization by histology, growth, and chromosomes. PMID- 4310096 TI - Antigenic specificity of hepatomas induced in strain-2 guinea pigs by diethylnitrosamine. PMID- 4310097 TI - Tumor-specific antigens: detection by local transfer of delayed skin hypersensitivity. PMID- 4310098 TI - Propagation and behavior in chicken kidney cultures of the agent associated with classical Marek's disease. PMID- 4310099 TI - Recovery of a hamster-specific, focus-forming, and sarcomagenic virus from a "noninfectious" hamster tumor induced by the Kirsten Mouse sarcoma virus. PMID- 4310100 TI - Localization of viral antigen in chickens infected with Marek's disease herpesvirus. PMID- 4310101 TI - Host-tumour relationship. XXV. Hyaluronidase activity in blood serum and ascitic fluid of rats during growth of transplanted tumours. PMID- 4310102 TI - Biological role of charge transfer complexes of aromatic hydrocarbon oxi derivatives in chemical carcinogenesis. PMID- 4310103 TI - Enhanced virus content of chicken tumours induced by the Schmidt-Ruppin strain of Rous sarcoma virus. PMID- 4310104 TI - [Use of the Silver-Shirkey lipiodol test in the study of intestinal absorption of lipids in children]. PMID- 4310105 TI - [Physiopathology of hypersomnias]. PMID- 4310106 TI - [Neurophysiological characteristics of nercoleptic symptoms]. PMID- 4310107 TI - [Monobrachial motorsensory form of multiple sclerosis]. PMID- 4310108 TI - A quantitative study on transformation of hamster embryo cells in vitro by murine sarcoma viruses (Harvey and Moloney). PMID- 4310109 TI - Study of poliovirus infection of human and monkey cells by indirect immunoferritin technique. PMID- 4310111 TI - Studies on EB virus of Burkitt's lymphoblasts. PMID- 4310110 TI - Specific requirement of serine for the growth of Newcastle disease virus. PMID- 4310112 TI - Cellular DNA and protein synthesis in reovirus-infected L cells. PMID- 4310113 TI - [Extra-adrenal lipolytic effect of an adrenocorticotropic pentacosapeptide: its influence on the free fatty acids in human plasma]. PMID- 4310114 TI - Newer viral exanthems. PMID- 4310115 TI - Nonchromaffin paraganglioma of the orbit. PMID- 4310116 TI - The effect of angiotensin on the heart rate of the turtle. PMID- 4310117 TI - Cuproproteins: a model and system derived from tricyanoaminopropene (TRIAP) and copper. PMID- 4310118 TI - Structure and function in mycoplasma. PMID- 4310119 TI - Peripheral neuropathy in tropical (nutritional) ataxia in Nigeria. Light and electron microscopic study. PMID- 4310120 TI - [Antimicrobial effect of the new oral antidiabetic HB 419]. PMID- 4310121 TI - Paradoxical sleep rebound in the rat. Effects of physical procedures involved in intracisternal injection. PMID- 4310122 TI - Inhibitory synaptic pathways linking specific and nonspecific thalamic nuclei. PMID- 4310123 TI - [Infectious power of Herpesvirus hominis DNA in cell culture]. PMID- 4310124 TI - [Treponema lipids. On the presence of a galactolipid in Treponema reiteri]. PMID- 4310125 TI - Osteocytic osteolysis. PMID- 4310126 TI - Correlation of psychological variables and progress in physical rehabilitation. PMID- 4310127 TI - Endocrine aspects of child psychoses. PMID- 4310128 TI - Studies on the 19S type immunological memory to phi chi 174 phage in an in vitro system. PMID- 4310129 TI - The antibody response and morphological changes following immunization of pig foetuses with phi chi 174 phage. PMID- 4310130 TI - The effect of sodium barbitone, alone and together with ACTH and amphetamine, on the behaviour of the rat in the multiple "T" maze. PMID- 4310131 TI - Pharmacological properties of feline red nucleus. PMID- 4310132 TI - Vesicular stomatitis virus (VSV) infection in rabbit eye: role of antibody and interferon. PMID- 4310133 TI - Isolation of the anti-inflammatory principles from Achillea millefolium (Compositae). PMID- 4310134 TI - Herpes simplex virus pneumonia. Occurrence in an allotransplanted lung. PMID- 4310135 TI - [Radioactive gold treatment of effusions caused by neoplasms]. PMID- 4310136 TI - [Rehabilitation of patients with malignant neoplasms in North Rhine-Westfalia]. PMID- 4310137 TI - [The carpal and tarsal tunnel syndrome; the quadrant syndrome]. PMID- 4310139 TI - Clinical experience using dehydrated corneal grafts in large corneal wounds. PMID- 4310138 TI - Regulation of insulin secretion. PMID- 4310141 TI - [Possible isolation of the ectromelic virus in the course of experiments on suckling mice]. PMID- 4310140 TI - [Incidence and level of influenza and adenovirus antibodies in various species of domestic animals]. PMID- 4310142 TI - [Studies on the development of skeletal muscles in the guinea-pig. II. Topochemical studies of some oxidoreductases]. PMID- 4310143 TI - [Presence of calciferol 3 in higher plants]. PMID- 4310144 TI - Studies on the metabolites of vitamin D. PMID- 4310145 TI - Changes in glycogen synthetase and phosphorylase during muscular contraction. PMID- 4310146 TI - Direct demonstration of superoxide anion production during the oxidation of reduced flavin and of its catalytic decomposition by erythrocuprein. PMID- 4310147 TI - On the formation of the superoxide anion radical during the reaction of reduced iron-sulfur proteins with oxygen. PMID- 4310148 TI - DNA-dependent RNA polymerase from E. coli: studies on the role of sigma in chain initiation. PMID- 4310149 TI - Inactivation of rat liver glycogen synthetase by 3':5'-cyclic nucleotides. PMID- 4310150 TI - Platelet aggregation. I. Regulation by cyclic AMP and prostaglandin E1. PMID- 4310151 TI - Muscle-type aldolase isolated from a liver tumor. PMID- 4310153 TI - [Protective effect of normal rat peritoneal fluid against lysis of erythrocytes by silica]. PMID- 4310152 TI - [Perfusion of the isolated liver: measurement of the enzymatic activities of the tissue]. PMID- 4310154 TI - [Delta-aminolevulinic-oxidative activity in neoplastic tissues of the digestive system]. PMID- 4310155 TI - [Adenosine deaminase in cell metabolism. I. Relation between enzyme activity and rate of DNA synthesis in various rat tissues]. PMID- 4310156 TI - [Kinetics of NADH accumulation. Method of studying the regulation of glycolysis in Hevea brasiliensis latex]. PMID- 4310157 TI - [Regulation of carbohydrate metabolism in vivo. II. Action of ethanol]. PMID- 4310158 TI - [Latent in vitro infection of hamster cells by SV5 and herpes virus. Electron microscope demonstration of a double viral production]. PMID- 4310159 TI - [Unusual cultural characteristics of a strain of herpesvirus hominis]. PMID- 4310160 TI - The epithelial-connective tissue junction as seen after enzymatic digestion. PMID- 4310161 TI - The origin of collagenase in periodontal tissues of man. PMID- 4310162 TI - The effect of alterations in external environment on the dentogingival junction. PMID- 4310163 TI - Transformation of odontogenic epithelium by polyoma virus in vitro. PMID- 4310164 TI - [Tumors of the soft tissues]. PMID- 4310165 TI - [Involvement and paralysis of the ulnar nerve in elbow arthrosis]. PMID- 4310166 TI - Mammary tumor virus (MTV) virions in a transplantable ependymoblastoam. PMID- 4310167 TI - Interstrain resistance to polyoma virus oncogenesis and runting in inbred mice treated with antilymphocyte serum (ALS). PMID- 4310168 TI - Effect of dihydroergotamine and propranolol on dibutyryl cyclic 3',5'-AMP-induced lipolysis in isolated rat fat cells. PMID- 4310169 TI - Correlation between propagation of a bovine enterovirus and development of receptor-like material in tissue mince. PMID- 4310170 TI - Tumor antigens. II. Immunological studies of tissue and tumor antigens and serum protein production by murine interstitial cell tumors of the testis and a hepatoma. PMID- 4310171 TI - Glucose-6-phosphate dehydrogenase in normal and malignant mouse tissues and cells propagated in vitro. PMID- 4310172 TI - Further observations on the inhibitory effect of myxoviruses on a transplantable murine leukemia. PMID- 4310173 TI - Influence of polyamines on induction of interferon and resistance to viruses by synthetic polynucleotides. PMID- 4310174 TI - Lipolytic activity of ribonucleotide and deoxyribonucleotide 3',5'-cyclic monophosphates in isolated rat fat cells. PMID- 4310175 TI - Methanol solubility of acid-precipitated proteins: a possible source of error in incorporation studies. PMID- 4310176 TI - Induction of tumor-specific transplantation immunity in hamsters with cell fractions from adenovirus and SV40 tumor cells. PMID- 4310177 TI - Typing of Herpesvirus hominis strains by a direct immunofluorescent technique. PMID- 4310178 TI - Effect of antibiotics on bacterial flora of rats with intestinal blind loops. PMID- 4310179 TI - Normal myocardial adenyl cyclase activity in hyperthyroid cats. PMID- 4310180 TI - Polyinosinic-cytidylic acid complex (poly I:C) and viral infections in mice. PMID- 4310181 TI - Concanavalin A-induced sensitization of mice to histamine. PMID- 4310182 TI - [A case of pulmonary adenomatosis]. PMID- 4310183 TI - Studies on experimental cerebral edema. I. Modification of glial triphosphatase activity in cerebral edema of the cat. PMID- 4310184 TI - Electron and fluorescence microscopical studies on the nucleus caudatus putamen of the rat after unilateral lesions of ascending nigro-neostriatal dopamine neurons. PMID- 4310185 TI - Herpes simplex encephalitis. PMID- 4310186 TI - Role of virucides in controlling virus dissemination by fabrics. PMID- 4310187 TI - Glial footplates in the bowfin. I. Fine structure and chemistry. PMID- 4310188 TI - [Characteristics of a bovine enterovirus (M80) combined with mucosal diseases]. PMID- 4310189 TI - Membranous structures associated with translation and transcription of poliovirus RNA. AB - Poliovirus RNA and proteins are synthesized in association with distinct membranous structures that were separated by means of Isopycnic centrifugation of cytoplasmic extracts in discontinuous sucrose-density gradients. Viral RNA is replicated in a structure that contains rapidly labeled replicative intermediate RNA and viral RNA polymerase associated with the smooth membrane fraction. In sucrose gradients this viral RNA replication complex is distributed at densities in the range of 1.12 to 1.18 grams per cubic centimeter. Viral proteins are synthesized on polyribosomes bound to membranes and sediment with polyribosomes at densities of less than 1.25 grams per cubic centimeter. PMID- 4310190 TI - [Current status of the question of specific antigens of virus-induced tumors and leukemias]. PMID- 4310191 TI - [Clinical syndromes of testicular dysgenesis in gynecological practice]. PMID- 4310192 TI - [Activity of 3beta-hydroxysteroid dehydrogenase and sec. alcohol dehydrogenase in the rat ovarian cycle]. PMID- 4310193 TI - Absence of catecholamines from islet cells of human pancreas and a beta-cell tumour in man. PMID- 4310194 TI - [Tinctorial properties of sulfated polyanion (SP 54)]. PMID- 4310196 TI - Growth in children with thalassaemia major and effect of two different transfusion regimens. PMID- 4310195 TI - [Functional development of the duodenal glands in the golden hamster]. PMID- 4310197 TI - [Histochemistry of articular cartilage and tissue of the chondro-osseous border of the head of the 1st metatarsal bone in normal state and in several pathological conditions (arthrosis)]. PMID- 4310198 TI - [Identification of alkylating agents. II. Identification of different classes of alkylating agents by a modification of the color reaction with 4-(4-nitrobenzyl) pyridine (NBP)]. PMID- 4310199 TI - [Chemical constitution and teratogenic effect in rats. II. N-alkylurea, N alkylsulfonamide, N,N-dialkylacetamide, N-methylthioacetamide, chloracetamide]. PMID- 4310200 TI - The effect of alpha-methyldopa on the vasoconstrictor responses of the rat mesenteric artery preparation to nerve stimulation. PMID- 4310201 TI - Effect of sympathomimetic amines on the response of the perfused mesenteric artery preparation to adrenergic nerve stimulation. PMID- 4310202 TI - [Contents of commercial papain]. PMID- 4310203 TI - [Pharmacological studies on isolated smooth muscle organs of the gold hamster]. PMID- 4310204 TI - [Phosphatases of mouse under effect of polyvinyl sulfate]. PMID- 4310205 TI - Effects of radiation on the central nervous system. PMID- 4310206 TI - [Presence of free radicals in frog heart]. PMID- 4310207 TI - [Sensitivity of man-hamster interspecies heteropolykaryocytes induced by SV5, to poliovirus]. PMID- 4310208 TI - [Australia-Antigen and Virushepatitis]. PMID- 4310209 TI - The peripheral neuropathy of Krabbe's (globoid) leukodystrophy. PMID- 4310210 TI - Motor unit frequency control in facial neuropathy. PMID- 4310211 TI - [Visual field defects in brain tumors]. PMID- 4310212 TI - From target-theory to molecular radiobiology. PMID- 4310213 TI - [Polyneuritis and polyneuropathies due to drug therapy]. PMID- 4310214 TI - [Urethral catheterization. Care and complications of the permanent cather]. PMID- 4310215 TI - [Lysosomes in the liver parenchymal cells of the spawning humpback salmon]. PMID- 4310216 TI - [Comparative autoradiographic study of the effect of polyoma virus on cell proliferation in embryonic tissues in mice and hamsters in vitro]. PMID- 4310217 TI - [Acute necrotic encephalitis. Apropos of 4 anatomo-clinical cases]. PMID- 4310218 TI - The inner membrane of the rat liver mitochondrion as the site of incorporation of radioactively labeled precursors into nucleic acid and protein in vitro. PMID- 4310219 TI - Purification and properties of 3-phosphoglyceric acid mutase from caprine erythrocytes. PMID- 4310220 TI - Phosphorylation linked to ascorbate oxidation in Mycobacterium phlei. PMID- 4310221 TI - Carbonyl groups associated with mitochondrial ATP synthesis. PMID- 4310222 TI - Phosphoserine phosphatase: development formation and hormonal regulation in rat tissues. PMID- 4310223 TI - Effects of dinitrophenol, dicyclohexyl carbodimide and oligomycin on respiration, glycogen synthesis, and glycolysis in Novikoff ascites-hepatoma cells. PMID- 4310224 TI - Isoenzymes of beta-isopropylmalate dehydrogenase from Pseudomonas aeruginosa. PMID- 4310225 TI - [Histochemical and histoenzymological properties of the epithelial band of the crista ampullaris]. PMID- 4310226 TI - [Camera-scintigraphy of the salivary glands with technetium 99m-pertechnetate]. PMID- 4310227 TI - [Differential diagnostial diagnostic value of the EEG lead with open eyes in intracranial processes. Behavior of the physiological and pathological activity]. PMID- 4310229 TI - [Analysis of the mechanism of poitive inotropic effect of agiotensin on the heart muscle]. PMID- 4310228 TI - [Relationship between surface potential and transmission inhibition in the superior cervical ganglion of the cat]. PMID- 4310230 TI - [Pharmacological effects of analogues of angiotensin substituted in position 5]. PMID- 4310231 TI - [Relationship between the tonus of the canine mesenteric vascular bed and its sensitivity to various vasoconstrictor agents]. PMID- 4310232 TI - [Conduction pathways of cat solar plexus sympathetic ganglia]. PMID- 4310233 TI - [Gastric juice release in dogs under the effect of injections of excessive amounts of ACTH or prednisolone]. PMID- 4310234 TI - Neuroendocrinological studies in mental disorders and psychotropic drugs. I. On the circadian rhythm of the plasma adrenocortical hormone in mental patients and methamphetamine- and chlorpromazine-treated animals. PMID- 4310235 TI - The determination of ammonia in arterial and venous blood by immediate fixation. PMID- 4310236 TI - Giant pleomorphic nuclei in the hamster-adenovirus tumor cell lines after treatment with HVJ. PMID- 4310237 TI - Increase of glycogen and oligosaccharide contents in ascites tumor cells under the influence of alkylating agents. PMID- 4310238 TI - Studies on siomycin. I. Physicochemical properties of siomycins A, B and C. PMID- 4310239 TI - Studies on the factor, responsible for increased triglyceride synthesis in tetracycline-treated rat. PMID- 4310240 TI - Studies on microbial degradation of carbenicillin. PMID- 4310241 TI - [Collagenase, with special reference to collagenolytic enzymes of animal tissue]. PMID- 4310242 TI - Notes on laboratory colonization of Culex tritaeniorhynchus summorosus, the principal vector of Japanese encephalitis in Japan. PMID- 4310243 TI - [Endocrine function of the kidney. Renal renin]. PMID- 4310244 TI - [Effect of some silica dust on the acid phosphatase activity in the erythrocytes]. PMID- 4310245 TI - [Effect of desoxyribonuclease on herpes simplex virus]. PMID- 4310246 TI - [Submicroscopic structure of a radiation mutant]. PMID- 4310248 TI - [Comparative study of the action of vancomycin and ristomycin on processes in Staphylococcus 209-K]. PMID- 4310247 TI - [Comparative study of bacterial phosphomonoesterases and PHOSPHODIESTERASES HYDROLYZING NUCLEIC ACIDS AND NUCLEOTIDES]. PMID- 4310249 TI - [Multiple primary colon cancer]. PMID- 4310250 TI - [Surgical treatment of the thoracic outlet compression syndrome]. PMID- 4310251 TI - Changes in ultrastructure and synaptic transmission in the sympathetic ganglion during various metabolic conditions. PMID- 4310252 TI - Presynaptic spike and excitatory postsynaptic potential in sympathetic ganglion: their modifications by pharmacological agents. PMID- 4310253 TI - Synaptic transmission in the senosry relay neurons of the thalamus. PMID- 4310254 TI - Forms of spontaneous and evoked postsynaptic potentials of cortical nerve cells. PMID- 4310255 TI - The functional organization within the ommatidium of the lateral eye of limulus. PMID- 4310256 TI - Effects of catecholamines in the cat superior cervical ganglion and their postulated role as physiological modulators of ganglionic transmission. PMID- 4310257 TI - Metabolic effects of nerve impulses and nerve-growth factor in sympathetic ganglia. PMID- 4310258 TI - [Transportal lipidic hepatography. Experiments and perspectives]. PMID- 4310259 TI - [Pharmacologic stimulation of the exocrine function in opaque contrast radiography of the pancreas]. PMID- 4310260 TI - Effect of carbon tetrachloride on the rates of lipid peroxidation and hydrolysis of pyrophosphates in isolated mitocondria. PMID- 4310261 TI - [Pharmacology of synaptic transmission]. PMID- 4310262 TI - [Studies in the field of chemical transmission of nerve excitation]. PMID- 4310263 TI - [Effect of phosphororganic substances on the transmission of neural ascitation]. PMID- 4310264 TI - [Generalized cytomegaly in children]. PMID- 4310265 TI - [Viremia in adenovirus infection]. PMID- 4310266 TI - [Disorders of the nerve trunks of the extremities in acute circulatory disorders]. PMID- 4310267 TI - [Treatment of peripheral nervous system diseases with Caucasian mumie]. PMID- 4310268 TI - [Anatomic-physiologic characteristics of the lateral femoral cutaneous nerve and its pathologic individuality]. PMID- 4310269 TI - [Benign pityriasic circinate erythema in a child: a new entity? 2 cases]. PMID- 4310270 TI - [Cholelithiasis associated with carcinoma of the gallbladder]. PMID- 4310271 TI - Metallocinium cations, nucleic acids and proteins. PMID- 4310272 TI - [Chromosome studies in malignant cellular proliferations of the endometrium]. PMID- 4310273 TI - [Glutamine synthetase in carps (Cyprinus carpio). Observations on tissue and intracellular distribution]. PMID- 4310274 TI - The hypersensitivity of adipose tissue to norepinephrine and other lipolytic agents during blockade of free fatty acids (FFA) mobilization. PMID- 4310275 TI - Distribution and metabolism of the periodate oxidation product of 9-beta-D ribosyl-6-methylthiopurine. PMID- 4310276 TI - Studies on immunosuppression by purine nucleoside analogues. I. Effects on the immune response to sheep red blood cells in mice. PMID- 4310277 TI - Model experiments for the study of iron transfer from transferrin to ferritin. PMID- 4310278 TI - Cooperative and non-cooperative conformational effects of the coenzyme on yeast glyceraldehyde-3-phosphate dehydrogenase. PMID- 4310279 TI - [Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa]. PMID- 4310280 TI - The effect of 5-hydroxytryptamine, dimethylphenylpiperazinium and acetylcholine on transmission and surface potential in the cat sympathetic ganglion. PMID- 4310281 TI - A new ganglion-stimulating compound: 2-imino-1,3-diaza-4-carboxyethyl cycloheptane hydrochloride (OG 30). PMID- 4310282 TI - Importance of the calcium ion in rhythmic fluctuation in renal pressure produced by angiotensin II. PMID- 4310283 TI - [Pharmacological studies of adenosine 3',5'-monophosphate and related compounds. 1. Effects of adenosine 3',5'-monophosphate and N6-2'-O-dibutyryl 3',5'-adenosine monophosphate on the renal function]. PMID- 4310284 TI - Antitumor activity of mycophenolic acid. PMID- 4310285 TI - Structure of the DNA of bacteriophage fd. I. Absence of non-phosphodiester linkages. PMID- 4310286 TI - Studies on the mechanism of action of salicylates. VII. Effect of a few anti inflammatory agents on uridine-5'-diphosphoglucose dehydrogenase. PMID- 4310287 TI - Water pollution. Microbiology. PMID- 4310288 TI - Outline of purification and some properties of histamine-sensitizing factor from Bordetella pertussis. PMID- 4310289 TI - Chemical carcinogenesis with DAB and lysosome. PMID- 4310290 TI - Antigenic structure and phase variation in Bordetella pertussis. PMID- 4310291 TI - [Therapy of hydrocyanic acid poisoning]. PMID- 4310292 TI - [Peculiarities of fine structure and virus reproduction]. PMID- 4310293 TI - Silicoextraction of senile and complicated cataracts. PMID- 4310294 TI - Histochemical studies on the release of the adrenergic transmitter by nerve impulses in combination with drugs, especially adrenergic neuron blocking agents. PMID- 4310295 TI - The similarities of the angiotensin and bradykinin action on the central nervous system. PMID- 4310296 TI - The adrenergic innervation of the human parotid gland. PMID- 4310297 TI - [Ischemic neuropathies: clinical and electromyographic examination]. PMID- 4310298 TI - [The effect of ACTH and prednisolone on the nuclear sex chromatin pattern]. PMID- 4310299 TI - [Electrocardiographic changes in diencephalic syndrome of the Cushing's syndrome type]. PMID- 4310300 TI - [Central cholinoreactive systems and adrenocorticotrophic function of the hypophysis]. PMID- 4310301 TI - [Changes of the 11-beta-hydroxylase activity in the adrenal glands under the effect of prolonged ACTH administration]. PMID- 4310302 TI - [Stress and compensatory hypertrophy of the adrenal glands in conditions of prolonged reserpine administration]. PMID- 4310303 TI - [Effects of sex hormones on the activity of 3-beta-ol-dehydrogenase in the rat adrenal cortex]. PMID- 4310304 TI - [Electromyography]. PMID- 4310305 TI - [Polyneuropathies]. PMID- 4310306 TI - [Chronic subdural hematoma]. PMID- 4310307 TI - [Enzymatic mechanisms of methylation]. PMID- 4310308 TI - [Functional disorders of the pituitary-adrenal cortex system in stomach cancer]. PMID- 4310309 TI - [An electron microscopic study of the morphology of pertussis microbes treated with ultrasound]. PMID- 4310311 TI - [Identification of an antigen isolated from B. pertussis with agglutinogen factor 2]. PMID- 4310310 TI - [The effect of various antibiotics on Cl. perfringens type A in experiments in vitro]. PMID- 4310312 TI - The epidemiology of amoebiasis. PMID- 4310313 TI - Involvement of adenosine 3',5'-monophosphate in release of ACTH. PMID- 4310315 TI - Persistent infection with herpes simplex virus in vitro. 1. Establishment and characteristics of persistent herpes simplex virus infection in Earle's L cells. PMID- 4310314 TI - Intermittent corticotrophin therapy. Study of lymphocyte transformation in vitro in rheumatoid arthritis. PMID- 4310316 TI - The oxidation-reduction potential of copper in cytochrome oxidase. PMID- 4310318 TI - Isolation of a tetrasaccharide common to MM, NN and MN antigens. PMID- 4310317 TI - Pleiotropic deficiency of carbohydrate utilization in an adenyl cyclase deficient mutant of Escherichia coli. PMID- 4310319 TI - Localization of isotope from (2-14C) glucose and (6-14C) glucose in deoxypentose moieties of herpes simplex DNA. PMID- 4310320 TI - Evidence that 3-phosphoserine may be a precursor of vitamin B6 in Escherichia coli. PMID- 4310321 TI - Effects of added nucleotides on renal carbohydrate metabolism. AB - 1. The regulatory effects that adenine nucleotides are known to exert on enzymes of glycolysis and gluconeogenesis were demonstrated to operate in kidney-cortex slices and in the isolated perfused rat kidney by the addition of exogenous ATP, ADP and AMP to the incubation or perfusion media. 2. Both preparations rapidly converted added ATP into ADP and AMP, and ADP into AMP; added AMP was rapidly dephosphorylated. AMP formed from ATP was dephosphorylated at a lower rate than was added AMP, especially when the initial ATP concentration was high (10mm). Deamination of added AMP occurred more slowly than dephosphorylation of AMP. 3. Gluconeogenesis from lactate or propionate by rat kidney-cortex slices, and from lactate by the isolated perfused rat kidney, was inhibited by the addition of adenine nucleotides to the incubation or perfusion media. In contrast, oxygen consumption and the utilization of propionate or lactate by slices were not significantly affected by added ATP or AMP. 4. The extent and rapidity of onset of the inhibition of renal gluconeogenesis were proportional to the AMP concentration in the medium and the tissue, and were not due to the production of acid or P(i) or the formation of complexes with Mg(2+) ions. 5. Glucose uptake by kidney-cortex slices was stimulated 30-50% by added ATP, but the extra glucose removed was not oxidized to carbon dioxide and did not all appear as lactate. Glucose uptake, but not lactate production, by the isolated perfused kidney was also stimulated by the addition of ATP or AMP. 6. In the presence of either glucose or lactate, ATP and AMP greatly increased the concentrations of C(3) phosphorylated intermediates and fructose 1,6-diphosphate in the kidney. There was a simultaneous rise in the concentration of malate and fall in the concentration of alpha-oxoglutarate. 7. The effects of added adenine nucleotides on renal carbohydrate metabolism seem to be mainly due to an increased concentration of intracellular AMP, which inhibits fructose diphosphatase and deinhibits phosphofructokinase. This conclusion is supported by the accumulation of intermediates of the glycolytic pathway between fructose diphosphate and pyruvate. 8. ATP or ADP (10mm) added to the medium perfusing an isolated rat kidney temporarily increased the renal vascular resistance, greatly diminishing the flow rate of perfusion medium for a period of several minutes. PMID- 4310322 TI - Intramolecular energy transfer in adrenocorticotropin. PMID- 4310323 TI - Reversible dissociation of yeast glyceraldehyde 3-phosphate dehydrogenase by adenosine triphosphate. PMID- 4310324 TI - Nuclear magnetic resonance study of the conformation of nicotinamide--adenine dinucleotide and reduced nicotinamide--adenine dinucleotide in solution. PMID- 4310325 TI - Kinetics of the oxidation of benzyl alcohol by acid permanganate. PMID- 4310326 TI - [Effect ofprogesterone and prolactin injection on gestation of Gambusia sp. females (Fishes Teleosts) without pituitaries]. PMID- 4310327 TI - In vitro ACTH assay: influence of strain on responsiveness of rat adrenals. PMID- 4310328 TI - [Ultrastructure and reproductive function of the adenohypophysis in teleostei]. PMID- 4310329 TI - The action of glycine on cortical neurones. PMID- 4310330 TI - Cytomegalovirus infection. A case report. PMID- 4310331 TI - Separation of specific antibodies to TSTAs of adeno 12 and polyoma tumors. PMID- 4310332 TI - The properties of sarcomas induced in Wistar rats byRous sarcoma virus (Schmidt Ruppin). PMID- 4310334 TI - Oocyte destruction and ovarian tumorigenesis after direct application of a chemical carcinogen (9:0-dimethyl-1:2-benzanthrene) to the mouse ovary. PMID- 4310333 TI - Activation of Rous virus in the transplanted golden hamster tumour with the aid of artificial heterokaryon formation. PMID- 4310335 TI - Pulmonary adenomatosis in opossums (Didelphis virginiana). PMID- 4310336 TI - Epidermal changes caused by squirrel poxvirus. PMID- 4310337 TI - A report of three bile duct carcinomas occurring in pigeons. PMID- 4310338 TI - Isolation and characterization of paecilomycerol, a new steroidal antiviral antibiotic. Studies on antiviral and antitumor antibiotics. XXI. PMID- 4310339 TI - Multiple endocrine adenoma peptic ulcer complex. Clinicopathological study of a case. PMID- 4310341 TI - Some characteristics of hemagglutination of certain strains of "IBV-like" virus. PMID- 4310340 TI - Terminal respiration in minute mutants of Drosophila. PMID- 4310342 TI - Application of antibiotic ointment to the site of venous catheterization--a controlled trial. PMID- 4310343 TI - Risk of infection with intravenous indwelling catheters: effect of application of antibiotic ointment. PMID- 4310344 TI - Mechanism of persistent herpes simplex virus infection in vitro. PMID- 4310345 TI - Metabolites of vitamin D3 and their biologic activity. PMID- 4310346 TI - The management of massive pulmonary embolism following hysterosalpingography. PMID- 4310347 TI - Studies on the biosynthesis of nuclear asis proteins. I. Incorporation of L lysine-14C in isolated rat hepatoma nuclei. PMID- 4310348 TI - The effect of zinc on the production of various toxins of Clostridium perfringens. PMID- 4310349 TI - The effect of calcium on the production of various toxins of Clostridium perfringens. PMID- 4310350 TI - Methods of sampling population of the Japanese encephalitis vector mosquitoes. A preliminary report. PMID- 4310351 TI - Syringocystadenoma papelliferum. PMID- 4310352 TI - Hypermineralocorticoid-induced hypertension. PMID- 4310353 TI - [Our clinical experience with a new hypertensive drug: beta-L-angiotensin II (Ciba 33'902 BA)]. PMID- 4310354 TI - Antibody response in piglets by simultaneous inoculation with attenuated viruses of Japanese encephalitis and hog cholera. PMID- 4310355 TI - Hemagglutin of Japanese encephalitis virus produced in embryonic swine kidney cell cultures. PMID- 4310356 TI - Growth characteristics and persistent infection of Japanese encephalitis virus in bovine kidney cell culture at different temperatures. PMID- 4310357 TI - Response of swine to an attenuated strain of Japanese encephalitis virus obtained by passage in bovine kidney cell cltures. PMID- 4310358 TI - Structural relationships in microbial peptides. PMID- 4310359 TI - Inhibitory effect of a synthetic interferon inducer on murine sarcoma and leukaemia virus infection in vitro. PMID- 4310360 TI - Neutralization of Graffi leukaemia virus. PMID- 4310361 TI - Cyclic 3',5'-adenosine monophosphate in human blood platelets. PMID- 4310362 TI - Rapid eye movements and dream imagery: are they related? PMID- 4310363 TI - Lung tap in childhood. Bacteria, viruses, and mycoplasmas in acute lower respiratory tract infections. PMID- 4310364 TI - Antibiotics and their effect on Bordetella pertussis in the nasopharynx. PMID- 4310365 TI - Comparative decay characteristics of the light generated free radical in chromatophores and chloroplasts. PMID- 4310366 TI - [Insulin stimulus therapy in collagen diseases]. PMID- 4310367 TI - [On the clinical findings and therapy of benign giant cell synovioma (pigmented villonodular synovitis, tenosynovitis and bursitis)]. PMID- 4310368 TI - Isolation and purification of an alkaline ribonuclease from human placenta. PMID- 4310369 TI - Subcellular distribution and function of ubiquinone in Salmonella typhimurium. PMID- 4310370 TI - Accumulation of azide in mitochondria and the effect of azide on energy metabolism. PMID- 4310372 TI - Histochemical studies on the distribution of esterases, monoamine oxidase and dephosphorylating enzymes in the area postrema of the squirrel monkey. PMID- 4310371 TI - [Interrelations of the regulatory areas of adrenal cortex and thyroid gland]. PMID- 4310373 TI - [Histochemical changes in the human liver in traumatic shock]. PMID- 4310374 TI - [Histochemical behavior of various dehydrogenases in the Leydig cells of the rat testis during simultaneous treatment with estrogen and gonadotropin]. PMID- 4310375 TI - Quantitative determination of phosphoinositides. PMID- 4310376 TI - The structure of myo-inositol pentaphosphates. PMID- 4310377 TI - Inositol phosphates, glycosides, and some 5-carbon cyclitols. PMID- 4310378 TI - Some characteristics of the d-glucose-6-phosphate: cycloaldolase (NAD+ dependent) from Neurospora crassa. PMID- 4310379 TI - Studies on myo-inositol metabolism in galactosemia. PMID- 4310380 TI - Physical properties and interactions of phosphoinositides. PMID- 4310382 TI - Aspects of phosphate ester chemistry as applied to the phosphoinositides. PMID- 4310381 TI - Ion-exchange chromatography of inositol polyphosphates. PMID- 4310383 TI - Functional activity in glands and synaptic tissue and the turnover of phosphatidylinositol. PMID- 4310384 TI - Acetylcholine-stimulated phosphodiesteratic cleavage of phosphoinositides: hypothetical role in membrane depolarization. PMID- 4310385 TI - Physiological significance of polyphosphoinositides in brain. PMID- 4310386 TI - Metabolism and function of polyphosphoinositides in nervous tissue. PMID- 4310387 TI - Polyphosphoinositide biosynthesis in developing rat brain homogenates. PMID- 4310389 TI - [Hydrocyanic acid poisoning in cattle caused by grazing on sugar cane (Saccharum officinarum) and supplemental feeding of fruits of the algarrobo tree (Prosopis juliflora)]. PMID- 4310388 TI - The metabolism of the polyphosphoinositides in kidney: studies on the phosphatidylinositol kinase. PMID- 4310390 TI - [Changes in urinary excretion of pregnanediol and pregnenolone in pregnancy after administration of ACTH]. PMID- 4310391 TI - [Erythropoietin mediation of the erythropoietic effect of ACTH, hydrocortisone and prednisolone]. PMID- 4310392 TI - Plasma cortisol monitoring and use of ACTH in asthma. PMID- 4310393 TI - Quantitative determination in urine of hippuric acid and m- or p-methylhippuric acid, metabolites of toluene and m- or p-xylene. PMID- 4310394 TI - [Thermosensitive vesicular stomatitis virus (SVS) mutants. Maturation mutants]. PMID- 4310395 TI - [Variations of hamster fibroblast antigenicity transformed by SV 40 then cloned (TSV5C12) as they are maintained in tissue culture or propagated in animals]. PMID- 4310396 TI - The effects of respiratory acidosis on a sensory relay system. PMID- 4310397 TI - Lipid content and composition of the tse-tse fly, Glossina morsitans Westwood. PMID- 4310398 TI - Rous sarcomas in mice: the chromosomal progression in primary tumours. PMID- 4310399 TI - Interference between tow strains of the mouse mammary tumour virus in the GR mouse strain. PMID- 4310400 TI - [Potentiating effect of choline on the action of phenylacetate. I. Effect on the isolated ileum of the guinea pig]. PMID- 4310401 TI - Sequential effects of chemically different carcinogens, dimethylnitrosamine and 4 dimethylaminoazobenzene, on hepatocarcinogenesis in rats. PMID- 4310402 TI - Transplantable mouse tumor line induced by injection of SV40-transformed mouse kidney cells. PMID- 4310403 TI - The lipids of normal diploid (WI-38) and SV40-transformed human cells. PMID- 4310404 TI - Some factors affecting carbohydrate metabolism in hepatic tissues of different growth rates. PMID- 4310405 TI - [Relative ultraviolet radiation target size of certain functions of the Polyoma virus]. PMID- 4310406 TI - Studies on P-450. VI. The spin state of P-450 solubilized from bovine adrenocortical mitochondria. PMID- 4310407 TI - Cerebral and visceral glycolipids in a case of Tay-Sachs disease. PMID- 4310408 TI - Spectrophotometric and electron spin resonance studies of NADH2-cytochrome c reductase complex. PMID- 4310410 TI - EPR studies on cytochrome oxidase at 20 degree K. PMID- 4310411 TI - Granular cell myoblastoma in the thyroid gland. Report of a case. PMID- 4310409 TI - Studies on chemically modified cytochrome c. II. The trinitrophenylated cytochrome c. PMID- 4310412 TI - The internal-external bonds of the memory process. PMID- 4310413 TI - Regenerative loop. PMID- 4310414 TI - Altered states of awareness. PMID- 4310415 TI - An experimental study on the phagocytosis of ascites tumor cells against benzidine yellow system pigments. PMID- 4310416 TI - Parallel changes in cytoplasmic and mitochondrial redox state of rat liver. Effects of ethanol, sorbitol and thyroid hormones. PMID- 4310417 TI - Effect of phenethyl alcohol on bacterial bioluminescence. PMID- 4310418 TI - [Physiological variations in the urinary excretion of aldosterone]. PMID- 4310419 TI - [Angiodysplasias of the hand]. PMID- 4310420 TI - [Histologic examination with the freezer in surgical practice]. PMID- 4310421 TI - [Fluorescent antibody studies in adenoviral pneumopathies with lethal outcome]. PMID- 4310423 TI - [Neonatal cytomegalovirosis]. PMID- 4310422 TI - [Reaction velocity of the enzymatic formation of angiotensin in vitro as a function of the electrolyte composition of the incubation medium]. PMID- 4310424 TI - [Clinical picture of ulcerogenic adenoma of the pancreas (Zollinger-Ellison syndrome)]. PMID- 4310425 TI - [The effect of ACTH on adrenergic agents in some forms of nervous, mainly hypothalamic, pathology]. PMID- 4310428 TI - [Para-influenzal infection of cattle (review of foreign literature)]. PMID- 4310426 TI - [Order of intracellular processes in stimulation of water and sodium transport with antidiuretic hormone in the frog bladder]. PMID- 4310427 TI - [Adenyl cyclase and the possible mechanism of action of some hormones]. PMID- 4310429 TI - [Nitrogenous components of the nutrient medium in culturing Clostridium perfringens type D]. PMID- 4310430 TI - [The etiology of infectious enterotoxemia in sheep]. PMID- 4310431 TI - Multiple tumors of the major salivary glands. PMID- 4310432 TI - Cancer of the sublingual salivary gland. PMID- 4310433 TI - Isolation of a canine herpesvirus from a dog with malignant lymphoma. PMID- 4310434 TI - Serologic evidence of bluetongue in wild ruminants of North America. PMID- 4310436 TI - Mucous-secreting cyst of the middle ear. Possible origin from the first pharyngeal pouch. PMID- 4310437 TI - Neonatal inclusion conjunctivitis in Australia. PMID- 4310435 TI - Secretory characteristics of phaeochromocytoma and related tumours. Their diagnostic and clinical significance. PMID- 4310438 TI - Antilymphocytic serum in experimental allergic encephalomyelitis. AB - Antilymphocytic and antithymic sera (raised in rabbits) are highly potent in preventing or alleviating experimental allergic encephalomyelitis in guinea-pigs. Good results are obtained when treatment is begun as late as 10 days after challenge. No protracted disease was seen from the use of antilymphocytic serum. Attempts to use this serum therapeutically once the disease was clinically established gave equivocal results. Antilymphocytic serum appears to have a non specific stressor effect as well as its specific action, and possibly this adrenocorticotrophic-hormone (antiphlogistic) effect may ameliorate a developing encephalitis. The presence of an antimacrophagic factor in antilymphocytic serum may be important in increasing local reaction to injection of the serum and perhaps also in diminishing the appearance of haematogenous elements in the nervous lesions. PMID- 4310439 TI - Mechanism of action of epinephrine and glucagon on the canine heart. Evidence for increase in sarcotubular calcium stores mediated by cyclic 3',5'-AMP. PMID- 4310440 TI - Pseudorenin. A new angiotensin-forming enzyme. PMID- 4310441 TI - Structural and functional characterization of dog heart microsomes. PMID- 4310442 TI - The nursing referral program in a V.A. hospital. PMID- 4310443 TI - [Inactivation of adrenocorticotropic hormone (ACTH). I. Inactivation of ACTH in the normal human plasma, and relationship between the structure and stability of ACTH]. PMID- 4310444 TI - [Inactivation of adrenocorticotropic hormone (ACTH). 2. Distribution of exogenous ACTH in vivo]. PMID- 4310445 TI - [Inactivation of adrenocorticotropic hormone (ACTH). 3. Inactivation of ACTH by tissues]. PMID- 4310446 TI - Radioimmunoassay of peptide hormones. PMID- 4310447 TI - [Diurnal variation of plasma cortisol concentration in patients with various diseases and negative feedback mechanism of the pituitary-adrenal axis]. PMID- 4310449 TI - [Clinical investigation on human growth hormone secretion in hypothalamo pituitary and thyroid diseases]. PMID- 4310448 TI - [Radioimmunoassay of human growth hormone and its clinical application]. PMID- 4310450 TI - [Adrenocortical hormones and aging process]. PMID- 4310452 TI - Cystosarcoma phyllodes. A study of 15 cases. PMID- 4310451 TI - [Iodine discharge test using KClO4 together with a small quantity of inorganic iodine]. PMID- 4310453 TI - Decreased interferon sensitivity and production in cells transformed by SV40 and other oncogenic agents. PMID- 4310454 TI - Induction experiments with adenovirus and polyoma virus transformed cell lines. PMID- 4310455 TI - Concomitant immunity in hamsters bearing DMBA-induced tumor transplants. PMID- 4310456 TI - The antigenic structure of nephroblastomas. PMID- 4310457 TI - Further experience using cryosurgery in otolaryngology. PMID- 4310458 TI - Pathologic findings in brain tumors treated with local methotrexate. PMID- 4310459 TI - A review of current laboratory studies with Entamoeba histolytica. PMID- 4310460 TI - Adrenal secretion of androgens and oestrogens. PMID- 4310461 TI - A comparison between the uptakes of radioactive perchlorate and iodide by rat and guinea-pig thyroid glands. PMID- 4310462 TI - The fate of free and conjugated oestrogens injected into the Graffian follicle of equines. PMID- 4310463 TI - Depressors of interferon synthesis: further studies on the production, action and properties of the so-called enhancer. PMID- 4310464 TI - Purification of Encephalomyocarditis virus. PMID- 4310465 TI - Radioautographic evidence of DNA synthesis in well-differentiated cells of human skin papillomas (verrucae vulgares). PMID- 4310466 TI - Antimicrobial therapy in theoy and practice. I. Clinical pharmacology. PMID- 4310467 TI - Antimicrobial treatment of pertussis. PMID- 4310468 TI - Cytomegalovirus infections in newborn infants. PMID- 4310469 TI - Simultaneous determination of thiamine and 2-(1-hydroxyethyl) thiamine in biological materials. PMID- 4310470 TI - Reaction products of vitamin D3 with Nield reagent, bisteroids A and B. PMID- 4310471 TI - Effect of vitamin D3 on the calcium binding factor in rat intestinal mucosa. PMID- 4310472 TI - Role of ring substitution on the inhibition of nicotinamide adenine dinucleotide dependent oxidations by 2-methyl-3-ortho-tolyl-6-hydroxy-4-quinazolone. PMID- 4310474 TI - The response of human gastric tissue eosinophils to ACTH infusion and to long term treatment with prednisone. PMID- 4310475 TI - The mechanism of photosynthesis. PMID- 4310476 TI - Polyol pathway in aorta: regulation by hormones. AB - Aldose reductase is present in human and rabbit aortas and provides a mechanism whereby hyper-glycemia can alter the metabolism of the arterial wall. Aortic sorbitol concentration is regulated by ambient glucose concentration and is increased by epinephrine, isoproterenol, dibutyryl-3',5'-adenosine monophosphate, ouabain, and angiotensin II. PMID- 4310477 TI - Cell transformation by viruses. PMID- 4310478 TI - Preliminary observations on Marek's disease in ducks and other avian species. PMID- 4310479 TI - Regional enteritis and entero-colitis: a study of 74 patients over 15 years. PMID- 4310480 TI - [Anterior tibial syndrome following lower leg surgery. False diagnosis as peroneal paresis]. PMID- 4310481 TI - [Serologic studies on the distribution of antibodies against the viruses of mucosal disease, of infectious rhinotracheitis or pustular vulvovaginitis and parainfluenza-3 in cattle of Hessen]. PMID- 4310482 TI - Cyclic 3',5'-nucleotide phosphodiesterase of fish (Salmo gairdnerii) brain. PMID- 4310483 TI - Influence of hyperthyroidism on the effects of norepinephrine on myocardial adenyl cyclase activity and contractile state. PMID- 4310484 TI - Effects of chlorpromazine and propranolol on in vitro thyroid activation by thyrotropin, long-acting thyroid stimulator and dibutyryl cyclic-AMP. PMID- 4310485 TI - Effect of ovariectomy on pituitary secretion of ACTH. PMID- 4310486 TI - Actinomycin D in vivo: paradoxical and nonspecific effects on adrenal cortex. PMID- 4310487 TI - In vitro release of ACTH: effects of potassium, calcium and corticosterone. PMID- 4310488 TI - Formation of estrogens by the pregnant mare. I. Metabolism of 7-3H dehydroisoandrosterone and 4-14C-androstenedione injected into the umbilical vein. PMID- 4310489 TI - Corticosteroid synthesis in adrenal enucleated rats before the onset of hypertension. PMID- 4310490 TI - Effects of ACTH and cyclic-AMP in vitro on incorporation of 3H-leucine and 14C orotic acid into protein and RNA in the presence of an inhibitor of cholesterol side chain cleavage. PMID- 4310491 TI - The separation of rat liver cells in colloidal silica-polyethylene glycol gradients. PMID- 4310492 TI - Autoradiographic studies of HeLa-S3 cells persistently infected with hemadsorption type 2 virus. PMID- 4310494 TI - [Clinical variaties of androgenism of ovarian origin. I. Stein-Leventhal syndrome, idiopathic hirsutism and ovarian thecomatosis]. PMID- 4310493 TI - Development of SV40 coat protein antigen in nonpermissive nuclei in heterokaryocytes. PMID- 4310495 TI - Measurement of plasma aldosterone by gas chromatography with electron capture detection. PMID- 4310496 TI - [Estriol "clearance" and creatinine clearance during normal spontaneous labor and labor induced by oxytocin infusion]. PMID- 4310497 TI - Effect of diphenylhydantoin on the metabolism of metyrapone and release of ACTH in man. PMID- 4310498 TI - Hyperaldosteronism in hypertensive congenital adrenal hyperplasia. PMID- 4310499 TI - Prophylaxis and treatment of endemic goiter in Peru with iodized oil. PMID- 4310500 TI - Evidence for a two-pool system governing the excretion of radioactive urinary estrogen conjugates during the first eight hours following the administration of extrone-6,7-3H to male subjects. Probable role of the enterohepatic circulation. PMID- 4310501 TI - Circadian rhythms of plasma growth hormone and cortisol after insulin. PMID- 4310502 TI - Constant light: effect on circadian pattern and phase reversal of steroid and electrolyte levels in man. PMID- 4310503 TI - Effect of circulating fragments of angiotensin II on radioimmunoassay in arterial and venous blood. PMID- 4310504 TI - Lasting biological effects of early environmental influences. IV. Notes on the physicochemical and immunological characteristics of an enterovirus that depresses the growth of mice. AB - Physicochemical and immunological techniques have been used in an attempt to characterize a filterable agent, separated from the intestines of mice raised under ordinary conditions of husbandry, which produces a lasting depression of weight in specific pathogen-free (SPF) mice when administered to them orally shortly after birth. Although this agent has not yet been identified, it will be tentatively designated here as enterovirus. The mouse enterovirus can be readily sedimented by ultracentrifugation and by precipitation at pH 4.3; it does not pass through cellophane membranes. Its infective power is completely destroyed by ultraviolet radiation, but is resistant to heating at 56 degrees C, exposure to ether, treatment with trypsin, ribonuclease, and deoxyribonuclease. Dialysis and treatment with ether and nucleases greatly increase the infective activity of the intestinal filtrates containing the enterovirus, a finding which suggests that these procedures eliminate or destroy some inhibitory substance(s). The mouse enterovirus causes hemagglutination of mouse red blood cells. When injected into rabbits, it elicits in them an immune response that renders their serum capable of neutralizing its weight-depressing activity. As measured by inhibition of hemagglutination or complement fixation, the sera of infected mice do not exhibit any significant activity against usual mouse viruses. Centrifugation of the mouse enterovirus in 50%-20% sucrose gradient gave almost complete recovery of the infectivity and of hemagglutinating activity in the same fraction. In contrast, the protein content of the material was distributed through the various fractions. Consequently, this procedure resulted in a marked increase of specific activity. PMID- 4310505 TI - Functional characterization of neuronal circuitry of frog cerebellar cortex. PMID- 4310506 TI - Neuronal interactions in frog cerebellum. PMID- 4310507 TI - Afferent inhibition at input to visual cortex of the cat. PMID- 4310508 TI - Posttetanic potentiation of monosynaptic and disynaptic actions from supraspinal structures on lumbar motoneurons. PMID- 4310509 TI - Bovine splenic nerve: characterization of noradrenaline-containing vesicles and other cell organelles by density gradient centrifugation. AB - 1. Homogenates of bovine splenic nerves were subjected to differential and sucrose density gradient centrifugation. From the low-speed supernatant a high speed sediment (mitochondria, lysosomes, microsomes and noradrenaline (NA) vesicles) was obtained. By density gradient centrifugation of this sediment it was shown that NA vesicles are slightly less dense than mitochondria, but denser than microsomes.2. In further experiments a mitochondrial and a microsomal sediment were obtained. The mitochondrial sediment was fractionated with a short centrifugation time over a density gradient ranging from 0.6 to 1.2 M sucrose. Mitochondria (fumarase and succinate-dehydrogenase) and lysosomes (acid ribonuclease and deoxyribonuclease) sedimented to the bottom of the tube. The highest concentration of NA vesicles was found in a medium position. There was only a small amount of microsomes (glucose-6-phosphatase) present.3. The microsomal sediment was centrifuged for 150 min over a density gradient ranging from 0.8 to 1.4 M sucrose. The microsomes remained on the top of the gradient. There were also some mitochondria and lysosomes present. The NA vesicles were found in highest concentration in the middle of the gradient (at about 1.2 M sucrose).4. With the use of these two density gradients, the subcellular distribution of dopamine-beta-hydroxylase, monoamine oxidase and ATPase was studied. Dopamine-beta-hydroxylase was found to be localized in the NA vesicles. Monoamine oxidase was mainly recovered in mitochondria; a small part of the enzyme appeared to be microsomal. ATPase was present in microsomal elements. PMID- 4310510 TI - Hydronephrosis secondary to ureteral obstruction by metastatic breast cancer. PMID- 4310511 TI - Progressive ventral sensory loss in sensory radicular neuropathy and hypertrophic neuritis. PMID- 4310512 TI - Clinical studies on interferon. I. Interferon production in children with viral diseases. PMID- 4310513 TI - Silent reversal of acromegaly: pituitary apoplexy resulting in panhypopituitarism. PMID- 4310514 TI - Inhibition of the effects of angiotensin II on adrenal steroid production by dietary sodium. AB - The pressor octapeptide, angiotensin II, can stimulate the production of aldosterone by the adrenal cortex. The present results show that in the dog a high-sodium diet can eliminate the steroidogenic action of angiotensin II, which is thus dissociated from the pressor action which remains. Angiotensin II was infused intravenously for 48 hours into conscious, undisturbed hypophysectomized dogs that were receiving each day either 60 or 200 mEq of dietary sodium. Blood pressure and secretion of aldosterone, corticosterone, and cortisol were measured (1) throughout the infusion in some dogs, and (2) at the end of the infusion in all dogs. In those dogs receiving 60 mEq of sodium, angiotensin II elevated the blood pressure and produced sustained increases of secretion of aldosterone, corticosterone, and cortisol. In those dogs receiving 200 mEq of sodium, angiotensin II, while retaining its pressor activity, had no effect on the production of aldosterone, corticosterone, or cortisol after 24 hours. Thus, if angiotensin II can produce hypertension clinically, there need not be secondary aldosteronism as well. PMID- 4310515 TI - Genetic control by the hr-locus of susceptibility and resistance to leukemia. AB - Leukemia was observed in 45 per cent of hairless mice at 8 to 10 months of age and 72 per cent at 18 months. The incidence of leukemia in normal heterozygous mice of the same age is about one per cent at 10 months and increases to 20 per cent at 18 months. Other tumors are rare; two mammary adenocarcinomas occurred in heterozygotes, and an epidermal squamous cell carcinoma was found in a hairless mouse. Murine leukemia virus was isolated from normal and leukemic mice of both genotypes on SWR/J- and C57L/J-METC, but not BALB/cJ-METC. If this virus is responsible for the leukemia in HRS/J mice, the mutant gene (hr) enhances susceptibility and the wild-type allele (+) induces resistance to leukemogenesis, i.e., malignant transformation of reticulo-endothelial tissues occurs rather than inhibition of viral replication as both genotypes harbor virus in high titers. The two types of HRS/J mice, hr/hr and hr/+, are congenic, i.e., they differ only with respect to one allele (hr or +) at the mutant locus. This single gene difference should lend itself to analysis of the interaction of a specific gene and murine leukemia virus. PMID- 4310517 TI - Stimulation of anterior pituitary adenyl cyclase activity and adenosine 3':5' cyclic phosphate by hypothalamic extract and prostaglandin E1. AB - Hypothalamic extract, containing the releasing factors for anterior pituitary hormones, within minutes stimulated adenyl cyclase activity and adenosine 3':5' cyclic phosphate (cyAMP) concentrations in rat anterior pituitary in vitro. Cerebral cortical extract was ineffective and hypothalamic extract had no effect on these parameters in posterior pituitary or thyroid. Prostaglandin E(1) also increased adenyl cyclase activity and cyAMP levels in anterior pituitary tissue. Although NaF augmented adenyl cyclase activity, it did not elevate cyAMP. Epinephrine, norepinephrine, histamine, serotonin, dopamine, and vasopressin did not increase either adenyl cyclase or cyAMP. The increased adenyl cyclase and cyAMP produced by hypothalamic extract was associated with greater luteinizing hormone release from anterior pituitary in vitro. PMID- 4310518 TI - Hemoglobin A: an electron paramagnetic resonance study of the effects of interchain contacts on the heme symmetry of high-spin and low-spin derivatives of ferric alpha chains. AB - Hemoglobin, the oxygen-binding heme protein of blood is composed of four subunits of two types, alpha and beta. Although the protein when isolated is diamagnetic, by oxidation it can be converted to various paramagnetic ferric forms exhibiting specific electron paramagnetic resonance (EPR) spectra. Using electron paramagnetic resonance, we have shown that the symmetry of the heme of isolated ferric alpha chains is different from that of the heme of these same subunits when associated with ferric beta chains in the parent tetramer. The high-spin form of the isolated ferric alpha chains shows a clearly resolved departure from tetragonal symmetry in contrast to ferrihemoglobin A, where the environment of the iron of all four chains is nearly tetragonal. This difference in heme symmetry suggests that the maintenance of tetragonal symmetry in the hemoglobin tetramer must be brought about by the configuration the alpha chains assume due to their contact with the beta chains. When isolated from the tetramer, some parts of the alpha chain must undergo physical displacement from a configuration that had been stabilized by the beta chains.Although differences in symmetry between monomer and tetramer are seen with high-spin forms, no such difference exists with two low-spin ferric forms. Here the symmetries of iron are primarily governed by the immediate ligand environment of the iron and not by the state of association of the protein. PMID- 4310516 TI - Replication and properties of DNA in nicotinamide adenine dinucleotide deficiency of Escherichia coli cells. AB - When niacin-requiring E. coli was starved of niacin, a precursor of nicotinamide adenine dinucleotide (NAD), the cells elongated and synthesis of DNA was inhibited while syntheses of RNA and protein continued. The cellular NAD concentration decreased to less than one tenth of the normal level in niacin deficiency, but no change in DNA ligase level was detected. The apparent inhibition of DNA synthesis can be explained as due to reduction in the activity of the cofactor, NAD, for the enzyme. The DNA synthesized in this state was small in an alkaline sucrose gradient but of normal size in a neutral sucrose gradient. The molecules had a double-stranded structure, as judged by hydroxyapatite chromatography. The small pieces of DNA were integrated into normal-size DNA molecules on addition of niacin, when the cellular NAD concentration was restored to the normal level but DNA synthesis was not. It is suggested that this small DNA is an intermediate in DNA replication. PMID- 4310519 TI - [Surgical method for polysyndaktylie]. PMID- 4310521 TI - [So-called mixed tumors of the sweat glands of the skin]. PMID- 4310520 TI - Metabolism in vitro of (4-14C) testosterone by liver homogenates of normal and carbon tetrachloride injured rats. PMID- 4310522 TI - [A study of replication of foot-and-mouth disease virus in infected cells]. PMID- 4310523 TI - Immunological studies on the membrane systems of cancer cells. 3. Immunospecificities of the mitochondria from virus-induced tumors by the precipitin reaction in agar gel. PMID- 4310524 TI - Cytochrome oxidase in a cytochrome oxidaserich submitochondrial membrane. PMID- 4310525 TI - Fractionation of proteins from perchloric acid filtrates of human sera and of its ethanol fractions by chromatography on DEAE-cellulose. PMID- 4310526 TI - [Granular cell myoblastoma of the urinary bladder: report of a case]. PMID- 4310527 TI - Mitral regurgitation in muscular subaortic stenosis. PMID- 4310528 TI - [Detection of complement-fixing antibodies against adenovirus in a population sample from Accra (Ghana)]. PMID- 4310529 TI - [Detection of complement-fixing antibodies against herpes simplex virus in a sample of population from Accra (Ghana)]. PMID- 4310530 TI - Ultrastructural study of epidermodysplasia verruciformis Lewandowsky and Lutz. Demonstrations of the virus and its correlation with clinical changes. PMID- 4310531 TI - Substrate specificity of adenyl cyclase from rat fat cell ghosts. PMID- 4310532 TI - EPR studies on reduction of oxygen to superoxide by some biochemical systems. PMID- 4310533 TI - The mechanism by which leucine and arginine stimulate insulin release in vitro. PMID- 4310534 TI - Subcellular distribution of two enzyme systems which degrade 3'-phosphoadenosine 5'-phosphosulfate ("active sulfate"). PMID- 4310536 TI - [Biosynthesis of progesterone in vitro in the corpus luteum of pseudopregnant rats: influence of Ca2+ and Mg2+ on the stimulating effects of luteinizing hormone, cyclic 3',5'-adenosine monophosphate or a high concentration of potassium]. PMID- 4310535 TI - [Wax D of a human virulent strain of Mycobacterium tuberculosis]. PMID- 4310537 TI - [Enzymatic activity of glycolysis in the iver of normal and diabetic subjects]. PMID- 4310538 TI - Relationship of phagocytic activity to pathogenicity of mouse hepatitis virus as affected by triolein and cortisone. PMID- 4310539 TI - Rhinovirus infection of vervet monkeys. A model of human rhinovirus disease. PMID- 4310540 TI - Osteogenesis imperfecta: effect of magnesium administration on pyrophosphate metabolism. PMID- 4310541 TI - A spin-labeled lipid for probing biological membranes. PMID- 4310542 TI - Glucose and galactose transport across a water-butanol-phospholipid interface. PMID- 4310543 TI - [Influence of cultivation in vitro on the enzyme model of intracranial tumors]. PMID- 4310544 TI - The intra-mitochondrial localization of flavoproteins previously assigned to the respiratory chain. PMID- 4310545 TI - [Properties and regulation of a phosphatase of Euglena gracilis, biosynthesis and inactivation]. PMID- 4310546 TI - A new sulfinic amino acid: homohypotaureine (3-aminopropanesulfinic acid). Isolation, determination and chromatographic behaviour compared with sulfinic and sulfonic derivatives of cysteine and homocysteine. PMID- 4310547 TI - [Presence of polyunsaturated acids in bacteria: isolation of hexatriacontapentaene-4,8,12,16,20-oic acid and acid analogs from Mycobacterium phlei lipids]. PMID- 4310548 TI - Electron histochemical study of 1:2-glycol groups in experimental hamster amyloid. PMID- 4310549 TI - Periodate oxidation of acid polysaccharides. II. Rates of oxidation of uronic acids in polyuronides and acid mucopolysaccharides. PMID- 4310550 TI - Production of free radicals in reduced glutathione and penicillamine by thermal hydrogen atoms and X-radiation. PMID- 4310551 TI - Influence of method of infection on the pathogenesis of infectious laryngotracheitis. PMID- 4310552 TI - Pathogenesis of bovine parainfluenza 3 virus infection in organ cultures. PMID- 4310553 TI - Primary liver tumours of cattle in Ceylon. PMID- 4310554 TI - A standardized serum neutralization test for feline viral rhinotracheitis. I. Virus assay. PMID- 4310555 TI - A standardized serum neutralization test for feline viral rhinotracheitis. II. The virus-serum system. PMID- 4310556 TI - [Estrogen secretory activity in chorionic tumors]. PMID- 4310557 TI - [Diagnosis of renovascular hypertension by means of differential renal function studies]. PMID- 4310558 TI - Various antibody holding status against viruses in Cercopithecus aethiops and Macaca irus. 3. The presence of antibodies to coxsackie, rubella, Japanese encephalitis, influenza and parainfluenza viruses. PMID- 4310559 TI - [Effect of heterogenic ribonucleic acids on the infection of cells by virus]. PMID- 4310560 TI - [Abdominal mass of uncertain nature]. PMID- 4310561 TI - [Neoplastic cells and L-glucose]. PMID- 4310562 TI - [Relationship between radiosensitivity and cell cycle time in 5 lines ascites hepatoma]. PMID- 4310563 TI - [Poisoning of 2 women performing artificial respiration in a case of poisoning with sodium and copper cyanides]. PMID- 4310564 TI - [Arterial hypertension and inadequate stimulation of aldosterone secretion. A new syndrome]. PMID- 4310565 TI - [Treatment of obstructive bronchopathies with long-acting tetracosactide (synthetic corticostimuline)]. PMID- 4310566 TI - [Activity of cytochrome-C-oxidase in mitochondria of liver tissue during transfusion of heterogenic blood]. PMID- 4310567 TI - [Latent anemias in patients with cancer]. PMID- 4310569 TI - Intestinal calcium absorption: nature of defect in chronic renal disease. AB - When compared to that of normal animals, calcium-binding protein activity of duodenal mucosa obtained from uremic rats was decreased. There was no change in this activity after vitamin D(3), therapy. In contrast, prior treatment with 25 hydroxycholecalcijerol resulted in increased transport of calcium-45 and calcium binding protein activity in the intestine. PMID- 4310568 TI - Some effects of pH and temperature upon normal human red cell adenosine triphosphate. PMID- 4310570 TI - Herpes simplex virus: dry mass. AB - Dry mass of herpes simplex virus particles was measured by quantitative electron microscopy after isolation by surface spreading and critical-point drying of infected cells. The core weighed about 2 x 10(-16) gram, the empty naked capsid 5 x 10(-16) gram, the full naked capsid 7 x 10(-16) gram, and the enveloped nucleocapsid 13 x 10(-16) gram. PMID- 4310571 TI - [Bacterial infections in a department of general medicine]. PMID- 4310572 TI - [Acute appendicitis with hematuria]. PMID- 4310573 TI - [Milk-alkali syndrome and chronic renal failure. (apropos of a case)]. PMID- 4310574 TI - [Multiple myeloma with colonic involvement]. PMID- 4310575 TI - [Hepatic coma, caused by viral hepatitis, successful treatment by hyperbaric oxygen]. PMID- 4310576 TI - Catechol and indole derivatives in a transplantable islet-cell tumour of the golden hamster. PMID- 4310577 TI - Picture of the month. Focal dermal hypoplasia (Goltz's syndrome). PMID- 4310578 TI - Ultrastructural observations on epidermal cells in Paget's disease of the breast. PMID- 4310579 TI - A role of the central nervous system in the cardiovascular actions of nicotine. PMID- 4310580 TI - [Calcium dependence of the action of drugs on guinea pig ileum and the relation to their mechanism of action]. PMID- 4310581 TI - Potentiation by desmethylimipramine of ganglionic inhibition by catecholamines. PMID- 4310582 TI - Release from brain tissue of compounds with possible transmitter function: interaction of drugs with these substances. PMID- 4310583 TI - Enhanced release of transmitter during sympathetic nerve stimulation in the presence of angiotensin. PMID- 4310584 TI - Inhibition of angiotensin pressor responses with diethyl-dithiocarbamate (DDC). PMID- 4310585 TI - The effect of theophylline on sodium transport across frog-skin in the absence of chloride. PMID- 4310586 TI - The mechanism of potentiation of inotropic responses to phenylephrine by theophylline. PMID- 4310587 TI - The effects of hyoscine and anticholinesterases on cholinergic transmission to the smooth muscle cells of the avian gizzard. AB - 1. Intracellular recordings were made from smooth muscle cells of the pigeon and chick gizzards. Hyoscine (10(-6) g/ml.) blocked, within 2 min, the excitatory junction potentials (E.J.P.s) evoked by transmural stimulation. As the amplitudes of E.J.P.s decreased, their durations also decreased. Hyoscine had no effect on the inhibitory junction potentials (I.J.P.s) evoked by transmural stimulation.2. Initially, physostigmine or neostigmine (10(-7) - 5 x 10(-6) g/ml.) caused a marked increase in the amplitudes of E.J.P.s, without affecting their time courses. Sometimes, anticholinesterases caused a single stimulus to evoke multiple E.J.P.s.3. After several minutes in the presence of high concentrations (10(-6) - 5 x 10(-6) g/ml.) of anticholinesterases the muscle cells were depolarized by about 15-20 mV, and thus the amplitudes of I.J.P.s evoked by transmural stimulation were larger than under control conditions. E.J.P.s summed at much lower stimulation frequencies than normal, an observation which indicated that high concentrations of anticholinesterases increased the durations of the E.J.P.s. Repetitive stimulation evoked a membrane depolarization which persisted for as long as 10 sec after stimulation was stopped.4. These results are discussed in terms of the action of the drugs at the nervesmooth muscle junction and on ganglion cells in the myenteric plexus. PMID- 4310588 TI - Effects of cyclic 3',5'-AMP and other adenine nucleotides on the melanophores of the lizard (Anolis carolinensis). AB - 1. Cyclic 3',5'-AMP has been reported to darken skins of the frog, Rana pipiens. This suggests that cyclic 3',5'-AMP may mediate the action of MSH on amphibian chromatophores. Since MSH also darkens skins of the lizard, Anolis carolinensis, we investigated the effects of cyclic 3',5'-AMP and other nucleotides on Anolis melanophores to determine whether cyclic 3',5'-AMP may be the intracellular mediator of hormone action on melanophores of another vertebrate class.2. Cyclic 3',5'-AMP, itself, causes a rapid melanin granule aggregation within melanophores of Anolis. This response is, however, somewhat nonspecific in that both 5'-ATP and 5'-ADP also lighten the skins by aggregating the melanin granules. Another nucleotide, 5'-AMP, darkens the skins by dispersing melanin granules. Cyclic 2',3'-AMP does not darken or lighten Anolis skins.3. Dibutyryl cyclic 3',5'-AMP, which is considered to be better able to penetrate membranes and resist degradation by a specific phosphodiesterase, maximally darkens Anolis skins, as does MSH. This darkening by the potent dibutyryl cyclic 3',5'-AMP suggests that cyclic 3',5'-AMP may be the intracellular mediator of melanin granule dispersion within Anolis melanophores leading to skin darkening.4. Other evidence supporting the first-messenger-second-messenger hypothesis for melanophore regulation is discussed.5. The differences in responses of Anolis melanophores to adenine nucleotides may relate to the ability of these agents to penetrate melanophore membranes; thus, the nucleotides could exert their effects either intracellularly or extracellularly on the plasma membrane. PMID- 4310589 TI - Automatic determination of lactic acid in blood. PMID- 4310590 TI - An azomethine-hypophosphorous acid addition compound as a new colorimetric reagent for iron. PMID- 4310591 TI - The effect of flavin coenzymes on the activity of erythrocyte enzymes. PMID- 4310592 TI - Effect of nitrate esters of androgen steroids on the succinate oxidase and NADH cytochrome c reductase activity of isolated rat liver mitochondria. PMID- 4310593 TI - Choline esterase activity in the nervous system and the innervated organs of the scorpion, Heterometrus fulvipes. PMID- 4310594 TI - Cycloheximide-induced ultrastructural changes in the adrenal cortex of the rat. PMID- 4310595 TI - Increased primary immune response and priming in mice to subimmunogenic doses of sheep erythrocytes by Bordetella pertussis. PMID- 4310596 TI - Generalized eruptive histiocytoma in a dog. PMID- 4310597 TI - Studies on the primary structure of ribosomal 28 S ribonucleic acid and its nucleolar precursors. Isolation of an electrophoretically homogeneous fragment rich in guanylic and cytidylic acids. PMID- 4310598 TI - Purification and properties of lysyl transfer ribonucleic acid synthetase from bakers' yeast. PMID- 4310599 TI - Purification and properties of a nucleoside triphosphate pyrophosphohydrolase from red cells of the rabbit. PMID- 4310600 TI - Lipid composition of rat liver plasma membranes. PMID- 4310601 TI - Independent smulation of secretion and protein snthesis in rat parotid gland. The influence of epinephrine and dibutyryl cyclic adenosine 3',5'-monophosphate. PMID- 4310602 TI - Hydrolysis of guanosine 5'-triphosphate associated wh binding of aminoacyl transfer ribonucleic acid to ribosomes. PMID- 4310603 TI - Mass spectrometric study on the mechanism of D-glucose 6-phosphate-L-myo-inositol 1-phosphate cyclase. PMID- 4310604 TI - Control of gluconeogenesis from amino acids in the perfused rat liver. PMID- 4310605 TI - Effects of glucagon on amino acid transport and utilization in the perfused rat liver. PMID- 4310606 TI - A new spin label specific for the active site of serine enzymes. PMID- 4310607 TI - The presence of tightly bound copper in ribulose diphosphate carboxylase from spinach. PMID- 4310608 TI - Action of adenosine 3',5'-monophosphate-dependent histone kinase in vivo. PMID- 4310609 TI - The treatment of neonatal Escherichia Coli meningitis. Case reports. PMID- 4310610 TI - [Formation of cyclic guanosine-3',5'-monophosphate in various rat tissues]. PMID- 4310611 TI - [A blood pressure increasing principle in the rat submaxillary gland]. PMID- 4310612 TI - [Mechanism of action of papaverine on isolated coronary vessels]. PMID- 4310613 TI - [Circulation and respiration in cyanide poisoning and therapy with ferrihemoglobin-forming and cobalt compounds]. PMID- 4310614 TI - [Influence of cardio- and vasoactive substances on phosphodiesterase activity]. PMID- 4310615 TI - [Effect of phosphodiesterase inhibitors on the heart]. PMID- 4310616 TI - [Mechanism of the antilipolytic effect of phenylisopropyladenosine (PIA) in vitro]. PMID- 4310617 TI - [Action of pH and PO2 on the membrane potential of epithelial receptor cells in the pseudobranch of a teleostean fish]. PMID- 4310618 TI - Non-identity between pulmonary bradykininase and converting-enzyme activity. PMID- 4310619 TI - [Cylindroma of the thoracic trachea]. PMID- 4310620 TI - Extrinsic nervous control of gastric motility. An experimental study in the cat. PMID- 4310621 TI - Antigens induced by the mouse leukemia viruses. PMID- 4310622 TI - Cardiopulmonary resuscitation. II. PMID- 4310623 TI - Hidradenocarcinoma: report of a case. PMID- 4310624 TI - Incidence of trophoblastic neoplasia in Iraq. PMID- 4310625 TI - [Histoenzymological investigation of exocrine pancreas. I. General view]. PMID- 4310626 TI - The scope of interanomeric glycosyl transfer reactions: hetero-dialdoside synthesis by enzymic glucosylation of D-galactose and D-mannose. PMID- 4310627 TI - Vitamin D esters: non-specific storage form of vitamin D in the rat. PMID- 4310628 TI - [Octopine dehydrogenase. Purification and catalytic properties]. PMID- 4310629 TI - [Structure and role of carbohydrate fractions of glycoproteins implicated in blood coagulation]. PMID- 4310630 TI - Peripheral neuropathy in a person sensitive to dynamite. PMID- 4310631 TI - Chromosome abnormalities in patients with syndactyly. AB - Chromosome studies on 105 patients with syndactyly included two trisomy-21 mongols, a chromatin-positive boy with 47, XXY, a chromatin-negative short girl with 45,X0 and a boy with a familial D/D translocation. Chromosome patterns were normal in the other cases which included three patients with acrocephalosyndactyly and one patient with oro-facial-digital syndrome.The incidence of chromosome abnormalies was greater than expected since syndactyly of the fingers is uncommon in the chromosome disorders.THIS INCIDENCE MAY BE RELATED TO THE INCREASED MATERNAL AGE (MEAN: 29.4 years) of the syndactyly group compared to maternal age (mean: 26.64 years) of the control group although, paradoxically, four mothers of the five patients with chromosome abnormalities were young. PMID- 4310632 TI - Angiographic and histologic studies of the vascularization of peripheral nerve tumors. PMID- 4310633 TI - Theory of step-wise excitation in gastropod heart. PMID- 4310634 TI - Antigenic relationship between SL-leukemia cells and other murine leukemia cells. PMID- 4310635 TI - The use of postal questionnaires in a service context. PMID- 4310636 TI - [New antigens in SV40 transformed cells. I. Demonstration of three new antigenic constituents in several cell lines of different species transformed by the SV40]. PMID- 4310637 TI - New antigens in cells transformed by the SV40 virus. II. Evidence of their cytoplasmic localization in a cell line (TSV5 CL2) of hamster fibroblasts transformed by SV40. PMID- 4310638 TI - Prevention of carcinogenesis by murine sarcoma virus (Harvey) following injections of immune sera during the latent period. PMID- 4310639 TI - Biological activity and separation of a leukaemogenic virus from murine sarcoma virus-Harvey (MSV-H). PMID- 4310640 TI - The inhibition by cytosine arabinoside of the replication of murine leukemia and sarcoma viruses in mouse embryo cultures. PMID- 4310641 TI - Rous sarcoma virus production in mixed cultures of mammalian Rous sarcoma cells and chick embryo cells. PMID- 4310642 TI - The formation of variants with a reversion of properties of transformed cells. 3. Reversion of the structure of the cell surface membrane. PMID- 4310643 TI - Murine sarcoma virus: titration patterns and interference by a murine leukemia virus. PMID- 4310644 TI - Studies on plasma membranes. IX. A survey of enzyme activities displayed by plasma membranes isolated from normal and preneoplastic livers and primary and transplanted hepatomas of the rat. PMID- 4310645 TI - Studies on plasma membranes. X. A survey of enzyme activities displayed by plasma membranes isolated from mouse liver and three mouse hepatoma strains. PMID- 4310646 TI - Assay of polyoma virus infectivity by haemagglutinin induction. PMID- 4310647 TI - Mitochondria of the higher plants. PMID- 4310648 TI - The analysis of body water compartments in postoperative craniotomy patients. 3. The effects of dexamethasone. PMID- 4310649 TI - Infections of the central nervous system due to pseudomonas aeruginosa. PMID- 4310650 TI - Scaling and refractoriness in pulse trains. PMID- 4310651 TI - Renal allotransplantation for bilateral renal tumors. PMID- 4310652 TI - Histochemical studies of small and large bowels. 1. Some enzymatic activities of normal human and laboratory animals. PMID- 4310653 TI - Histochemical studies of small and large bowels. 2. Histological and histochemical changes of human small intestine in various pathological states (results of intestinal biopsies in 102 cases). PMID- 4310654 TI - [Biosynthesis and inactivation of the pineal body hormones]. PMID- 4310655 TI - The blood vessel permeability of peripheral nerve during primary demyelination and the effect of A.C.T.H. therapy on the permeability and on the functional disability. PMID- 4310656 TI - Outside time and inside time. PMID- 4310657 TI - Post-vaccinial sensory polyneuropathy with myoclonus. PMID- 4310660 TI - Pharmacology of synaptic monoamine transmission. PMID- 4310658 TI - Sleep, natural and unnatural. PMID- 4310661 TI - [Paraneoplastic encephalomyelitis. Apropos of an anatomical and clinical observation]. PMID- 4310662 TI - [Case of thorotrast-induced canceer of the liver with epidural metastasis to the spinal cord]. PMID- 4310663 TI - [Incidence of adenovirus antibodies in patients with various clinical forms of chronic rheumatism]. PMID- 4310664 TI - A progress report on aftercare. PMID- 4310665 TI - Tumours of the chemoreceptor system. PMID- 4310666 TI - [Guyon's tunnel syndrome]. PMID- 4310667 TI - Platelet aggregation. II. Adenyl cyclase, prostaglandin E1, and calcium. PMID- 4310668 TI - Application of electron spin resonance to the study of the structure of human serum lipoproteins. PMID- 4310669 TI - Diagnosis of herpes virus hominis keratitis by immunofluorescence. PMID- 4310670 TI - Studies on 2',3'-cyclic nucleotide-3'-phosphohydrolase from brain. PMID- 4310671 TI - 3-Deoxy-D-gluco-octulosonic acid. PMID- 4310672 TI - [Neoplasms of small salivary glands of the oral cavity]. PMID- 4310673 TI - [A method for the preparation of ceramide from brain gangliosides and the nature of their sphingosine bases]. PMID- 4310674 TI - [Evolution of endopeptidases. X. Cleavage specificity of low molecular weight protease from Astacul leptodactylus Esch]. PMID- 4310675 TI - Electroencephalogram and rapid eye movements during free imagery and dream recall. PMID- 4310676 TI - [Sialo-mucoid in the nasal secretion and virus infections]. PMID- 4310677 TI - [Food poisoning epidemic caused by Clostridium perfringens]. PMID- 4310678 TI - [Cl. welchii as the cause of food poisoning]. PMID- 4310679 TI - [Nonchromaffin paraganglioma with retroperitoneal localization]. PMID- 4310680 TI - [Study of steroid estrogens in their AZO compound forms by thin-layer chromatography on silica gels]. PMID- 4310681 TI - [Glucocorticoid function of the adrenal cortex in various primary lesions of the liver]. PMID- 4310682 TI - [17-ketosteroids, 17-hydroxycorticosteroids and dehydroepiandrosterone in diurnal urine in chronic toxoplasmosis]. PMID- 4310683 TI - [Condition of excitability of the adrenoreactive structures of the central nervous system during ACTH and hydrocortisone administration]. PMID- 4310684 TI - [Corticosteroid biosynthesis in the adrenal glands of human fetuses. II. Conversion of pregnenolone and effect of ACTH on hydrocortisone synthesis]. PMID- 4310685 TI - [Significance of the hypophysis in plasma hydrocortisone binding with transcortin in guinea pigs]. PMID- 4310686 TI - [Effects of sex factors on the androst-4-en-3,17-dione formation]. PMID- 4310687 TI - [The effect of thyroxine on the concentration of acetylation coenzyme and nicotinamide-adenine-dinucleotide in the liver of albino rats of various ages]. PMID- 4310688 TI - [The brain injured following initial care]. PMID- 4310689 TI - The complementary aspect in the relation between biological and psychodynamic psychiatry. PMID- 4310690 TI - [Our experience with hormone treatment of infantile encephalopathies with spasms and hypsarrhythmia]. PMID- 4310691 TI - [Hormone therapy of various epileptic disorders in childhood]. PMID- 4310692 TI - [Metabolism of tryptophan in the course of corticosteroid therapy of some infantile convulsive syndromes]. PMID- 4310693 TI - [Our experience with treatment of infantile encephalopathies with ACTH and corticoids]. PMID- 4310694 TI - [Comparison of treatment with ACTH and Nitrazepam in some forms of infantile convulsive syndromes]. PMID- 4310695 TI - [Variety of electroencephalographic and clinical responses to ACTH treatment in infantile epilepsy]. PMID- 4310696 TI - [Therapeutic considerations on hypsarrhythmic encephalopathy]. PMID- 4310697 TI - [Use of synthetic ACTH in hypsarrhythmia]. PMID- 4310698 TI - [Corticosteroid therapy of acute viral ataxia in the pediatric age]. PMID- 4310699 TI - [Our experience with the clinical and therapeutic aspects of spasms in flexion]. PMID- 4310700 TI - [Action of ACTH in a case of photogenic epilepsy]. PMID- 4310701 TI - [Results of corticotropin therapy in a subject with attacks of speech arrest]. PMID- 4310702 TI - [ACTH therapy of 80 patients with non-hypsarrhythmic epilepsy in the evolutive age]. PMID- 4310703 TI - [Examination of case histories of some myoclonic encephalopathies collected at the Clinica Pediatrica of Padua]. PMID- 4310704 TI - [ACTH therapy of infantile epileptic disorders]. PMID- 4310705 TI - [Changes of cortisolemia during ACTH therapy in subjects with convulsive encephalopathies]. PMID- 4310706 TI - [On the biological properties of some fibrinogen degradation products (FDP)]. PMID- 4310707 TI - Carcinoma of the lung in Iceland. A summary and some reflections concerning more recent principles for diagnosis and treatment. PMID- 4310708 TI - Chemodectoma of the lung. PMID- 4310709 TI - [Result of postoperative radiotherapy of breast carcinoma]. PMID- 4310710 TI - [Corticotherapy in bronchial asthma in adults, based on personal observations]. PMID- 4310711 TI - [Possibilities and limits of the fluorescent antibody detection of ectromelia virus in organ tissue]. PMID- 4310712 TI - Immunological relationships of some oncogenic DNA viruses. I. Transplantation immunity studies. PMID- 4310713 TI - Immunological relationships of some oncogenic DNA viruses. II. Primary tumour inhibition studies. PMID- 4310714 TI - Lipids of ocular tissues. I. The phospholipids of mature rabbit and bovine lens. PMID- 4310715 TI - Phospholipids in tissues of the eye. 3. Composition and metabolism of phospholipids in human lens in relation to age and cataract formation. PMID- 4310716 TI - Diether phosphinate lecithin: chemical synthesis and effects on phospholipase C. PMID- 4310717 TI - Carbohydrate components of bovine-kidney gangliosides. PMID- 4310718 TI - Heterogeneity of lipid composition of microsome subfractions from aorta and liver. PMID- 4310719 TI - The effect of polypeptide hormones on lipid monolayers. ii. The effect of insulin analogues, vasopressin, oxytocin, thyrocalcitonin, adrenocorticotropin, and 3',5'-cyclic AMP on the uptake of Ca2+ by monomolecular films of monooctadecyl phosphate. PMID- 4310720 TI - Phosphate transport in Bacillus cereus. PMID- 4310721 TI - Enrichment of 5'-nucleotidase in membrane fragments isolated from Acanthamoeba sp. PMID- 4310722 TI - Mechanism of the "antidiuretic hormone-like" action of hypertonic media on the frog urinary bladder. PMID- 4310723 TI - On the impermeability of the outer mitochondrial membrane to cytochrome c. I. Studies on whole mitochondria. PMID- 4310724 TI - Evidence on the safety and efficacy of live poliomyelitis vaccines currently in use, with special reference to type 3 poliovirus. PMID- 4310725 TI - [Comparative observations relative to the encystment of Entamoeba histolytica in vivo and in vitro]. PMID- 4310726 TI - Drug therapy of amoebiasis. PMID- 4310727 TI - Drug trials in amoebiasis. PMID- 4310728 TI - A serological study of Cytomegalovirus infection in the population of Easter Island. PMID- 4310729 TI - Pathogenesis of hypertension and implications for its therapeutic management. PMID- 4310730 TI - Long-lasting synaptic inhibition and its transmitter in the snail Helix aspersa. PMID- 4310731 TI - [Long-term therapy of immunologic diseases with special reference to the use of immunosuppressive agents]. PMID- 4310732 TI - [Listeria monocytogenes. XII. 1. Selective culture media. 2. Search for Listeria monocytogenes in vaginal secretions]. PMID- 4310733 TI - [The use of the agar diffusion reaction for the diagnosis of Cl. perfringens]. PMID- 4310734 TI - Angiography of vascular lesions of the face and neck. PMID- 4310735 TI - Role of ACTH in the secretion of free dehydroepiandrosterone and its sulfate ester in man. PMID- 4310736 TI - Studies on heterologous antilymphocyte and antithymocyte sera. IV. Further evidence for a preferential effect on antigen-sensitive cells. PMID- 4310737 TI - In vitro immune responses of rabbits with persistent adenovirus type 5 infection. PMID- 4310738 TI - Reaginic-type of antibody in mice stimulated by extracts of Bordetella pertussis. PMID- 4310739 TI - Varying specificity of systemic lupus erythematosus sera for histone fractions and a periodate-sensitive antigen associated with histone. PMID- 4310740 TI - Studies on the neutralization of Japanese encephalitis virus. II. Variations in reaction properties of virus to antibody during replication in PS cell cultures. PMID- 4310741 TI - Ultrastructure of galactogen in the albumen gland of Helix pomatia. PMID- 4310742 TI - [Case of cancer and cystosarcoma phyllodes of the bilateral breast]. PMID- 4310743 TI - Inhibition of herpes virus adsorption on cells by protamine. PMID- 4310744 TI - Thermoinactivation of HF and M strains of herpes simplex virus in various conditions. PMID- 4310745 TI - Antimicrobial susceptibility of enterobacteriaceae and nonfermenting gram negative bacilli. PMID- 4310746 TI - The use of the complement fixation test for indication of specific antigen in chicken embryo tissue cultures with the different sensitivity to Rous virus. PMID- 4310747 TI - Peculiarities of complement fixation test in hamsters with sarcoma caused by various strains of Rous sarcoma virus. PMID- 4310748 TI - Antigenic characteristics of tumors induced in Syrian hamsters by Simian virus 40. PMID- 4310749 TI - Femoral neuropathy in scurvy. PMID- 4310750 TI - [Effect of the hyperthyroid state duration on the blood cholesterol conte and pharmacodynamic action of ACTH and epinephrine against this background in rats]. PMID- 4310751 TI - [Corticosteroid biosynthesis in the rat adrenal glands in normal conditions and under ACTH stimulation. Participation of progesterone]. PMID- 4310752 TI - [Problems of the mentally ill outside the hospital (remarks of the social assistant)]. PMID- 4310753 TI - [Arrhenoblastoma of the ovary. 3rd case reported in Venezuela]. PMID- 4310754 TI - Lung cancer in a mining district in Rhodesia. PMID- 4310755 TI - [Behavior of succinic acid dehydrogenase and cytochrome oxidase in Trichomonas vaginalis]. PMID- 4310756 TI - Parasitological studies on liver abscess in Cheju Island. PMID- 4310757 TI - The neoductuli in the rabbit liver with dietary, experimental icterogenic steatosis (Chisiu type). (Histochemical and histoenzymatic study). PMID- 4310758 TI - The relative role of recapture and of de novo synthesis for the maintenance of neurotransmitter homeostasis in noradrenergic nerves. PMID- 4310759 TI - Postpartum amenorrhea-galactorrhea of hypothyroidism. PMID- 4310760 TI - Alveolar cell carcinoma. An electron microscopic study. PMID- 4310761 TI - Extensive pseudomonal pneumonia ultimately responding to polymyxin therapy. PMID- 4310762 TI - Pyrophosphate and diphosphonates in calcium metabolism and their possible role in renal failure. PMID- 4310764 TI - Primary gene products of an arbovirus. PMID- 4310763 TI - Fructose-1,6-diphosphatase of Acinetobacter: inhibition by ATP and citrate. PMID- 4310765 TI - [Radioimmunoassay of the hypophyseal function of somatotropin, gonadotropins and corticotropin]. PMID- 4310766 TI - Cyclic modes in neural net models. PMID- 4310767 TI - Experimental applications of endoscopy. PMID- 4310768 TI - The Zollinger-Ellison syndrome in a child. AB - The Zollinger-Ellison syndrome was encountered in a boy aged 11 years who presented with a bulbar duodenal ulcer causing intractable pain and bleeding. The diagnosis was made by finding an overnight fasting gastric secretion of 1,300 ml containing 134 m-equiv/HCl, and little change of secretion after maximal histamine stimulus. A circumscribed non-beta islet cell pancreatic tumour was excised, with antrectomy. Postoperative acid secretion was normal and the boy was well after being followed up for 15 months. The diagnosis and management are discussed, as the view that total gastrectomy must be performed in all cases of the Zollinger-Ellison syndrome is questioned. PMID- 4310769 TI - Rapid tests of adrenal cortical function using plasma 11-hydroxycortico-steroid determination. PMID- 4310770 TI - "Activation" of vitamin D by the liver. AB - Isolation of the liver from the circulation of rats eliminates almost completely their ability to convert [1,2]-(3)H vitamin D(3) into its biologically active metabolite, 25-hydroxycholecalciferol, as well as certain other metabolites. It is concluded that the liver is the major if not the only physiologic site of hydroxylation of vitamin D(3) (cholecalciferol) into 25-hydroxycholecalciferol. The osteodystrophy and the higher requirements for vitamin D observed in hepatic insufficiencies may be due to an inability of the liver to transform vitamin D into its metabolically active form. PMID- 4310771 TI - Hypophosphatasia: a case report. PMID- 4310772 TI - Adenoid-cystic carcinoma of the larynx. PMID- 4310773 TI - Granular cell myoblastoma of laryngopharynx. PMID- 4310774 TI - Polymyxin Bduced respiratory paralysis reversed by intravenous calcium chloride. PMID- 4310775 TI - [Screening and transcortin binding capacity of ectopic ACTH producing lung cancer]. PMID- 4310776 TI - Cutaneous histiocytomas of dogs. PMID- 4310777 TI - Yaba virus tumors. PMID- 4310778 TI - Some implications of sleep research for psychiatry. PMID- 4310779 TI - Sleep characteristics of patients with angina pectoris. PMID- 4310780 TI - [Endocrinological study of arrhenoblastoma]. PMID- 4310781 TI - Physical and chemical studies on ceruloplasmin: crystallization of desialized human ceruloplasmin asialoceruloplasmin. AB - Completely or partially desialized human ceruloplasmin crystallizes as blue hexagonal prisms terminating at both ends in shallow pyramids. PMID- 4310782 TI - Tumors of the chest wall. PMID- 4310783 TI - Peripheral neuropathy in experimental coyotillo poisoning in goats. PMID- 4310784 TI - [Free oxidation in the respiratory chain as a mechanism of oxidative hydroxylation]. PMID- 4310785 TI - Host specificity and pathogenicity of pox viruses from wild birds. PMID- 4310786 TI - Structure of p-bromocarbobenzoxy-glycyl-prolyl-leucyl-glycine. PMID- 4310787 TI - Dynamics of pyridine nucleotide in the placenta and the effect on it of sexagens. PMID- 4310788 TI - Renal and splenic pituitary homograft to hypophysectomized rat during pregnancy and lactation. PMID- 4310789 TI - Diagnosis of non-depolarising block. PMID- 4310790 TI - Formation of hemichromes from oxidized hemoglobin subunits. PMID- 4310791 TI - Localization of the atractyloside-sensitive nucleotide binding sites in rat liver mitochondria. PMID- 4310792 TI - Reconstitutively active NADH dehydrogenase. PMID- 4310793 TI - Cytochemical studies on the second gradient axis of fertilized oyster eggs. V. On the activity of glucose-6-phosphatase, glucose-6-phosphate dehydrogenase and malate dehydrogenase and the relationship between egg nucleolus and egg periphery. PMID- 4310794 TI - Effect of ketone bodies and ACTH on the transmethylation reaction (S adenosylmethionine dependent system) in rats. II. PMID- 4310795 TI - Studies on rat-liver phosphatases. I. Effect of acetoacetate. PMID- 4310796 TI - Quantitative study on the transpulmonary passage of tumor cells. PMID- 4310797 TI - Specific gravity of liver cells during hepatocarcinogenesis by N nitrosodiethylamine in rats. PMID- 4310798 TI - Electron spin resonance study on the free radicals produced from carcinogenic aminonaphthols and N-hydroxy-aminonaphthalenes. PMID- 4310799 TI - Malignant transformation of an established kidney cell line from African green monkey by the Schmidt-Ruppin strain of Rous sarcoma virus. PMID- 4310800 TI - Follow-up study of nerve lesions in leprosy using the time intensity curve test. PMID- 4310801 TI - The localization of glucose-6-phosphate hydrolysing enzyme in hepatocytes, red blood cells and leukocytes in the liver of the newborn rat. PMID- 4310802 TI - Electron microscopic studies of experimental viral hepatitis in mice. I. Virus Particles and their relationship to hepatocytes and kupffer cells. PMID- 4310803 TI - Electron microscopic studies of experimental viral hepatitis in mice. II. Ultrastructural changes of hepatocytes associated with virus multiplication. PMID- 4310804 TI - Determination of vitamin D in blood. PMID- 4310805 TI - [Passive transfer of acquired resistance by peritoneal exudate cells and spleen cells of mice immunized with ectromelia virus]. PMID- 4310806 TI - Anti-lipolytic effects of beta-hydroxybutyrate. PMID- 4310807 TI - Mechanism of action of antilipolytic agents: comparison of the effects of insulin, tolbutamide, and phenformin on lipolysis induced by dibutyryl cyclic AMP plus theophylline. PMID- 4310808 TI - Central American leishmaniasis. PMID- 4310809 TI - [Catecholamines and adrenergic drugs. Pharmacodynamics and clinical aspects of anesthesiology]. PMID- 4310810 TI - [Current data on steroid metabolism in chronic leukemia]. PMID- 4310811 TI - Leukaemia and cytomegalovirus infection. PMID- 4310812 TI - Growth of vesicular stomatitis virus in Ehrlich ascites tumour cells. An electron microscopic study. PMID- 4310813 TI - Dose effects of chlorpromazine on human sleep. PMID- 4310814 TI - The effects of local x irradiation on the relative rates of incorporation of thymidine-methyl-5-3H and cytidine-5-3H into mitochondrial and nuclear DNA of Morris hepatoma 3924A. PMID- 4310815 TI - Whole-lung irradiation for metastatic tumor. PMID- 4310816 TI - [Lactate production from fumarate by Rana esculenta liver mitochondria]. PMID- 4310817 TI - Carinal resection, left pneumonectomy, and right lung anastomosis for adenocystic basal cell carcinoma (cylindroma). PMID- 4310818 TI - [3 cases of phosphoric ester poisoning]. PMID- 4310819 TI - Neuromuscular blocking activity of gentamicin in cats and mice. PMID- 4310820 TI - [Pathogenesis and symptomatology of adrenal gland insufficiency in children]. PMID- 4310821 TI - [Current principles and results in the treatment of malignant tumors in children]. PMID- 4310822 TI - [Selective microdochectomy for the diagnosis and therapy of pathologic breast secretion]. PMID- 4310823 TI - Destruction and restoration of the insulin effector system of isolated fat cells. PMID- 4310824 TI - Purification and properties of nascent f2 phage ribonucleic acid. PMID- 4310825 TI - Regulation of inducible enzyme synthesis in Escherichia coli by cyclic adenosine 3', 5'-monophosphate. PMID- 4310826 TI - Repression of beta-galactosidase synthesis by glucose in phosphotransferase mutants of Escherichia coli. Repression in the absence of glucose phosphorylation. PMID- 4310827 TI - Two reduced nicotinamide adenine dinucleotide dehydrogenases from the photosynthetic bacterium, Rhodospirillum rubrum. PMID- 4310828 TI - Interaction of coenzyme with differently prepared zinc-free (apo) horse liver alcohol dehydrogenases. PMID- 4310829 TI - Azotobacter vinelandii ribonucleic acid polymerase. 8. Pyrophosphate exchange. PMID- 4310830 TI - Purification and properties of two types of diphosphopyridine nucleotide-linked glycerol 3-phosphate dehydrogenases from chicken breast muscle and chicken liver. PMID- 4310831 TI - Isolation of human hepatocuprein and cerebrocuprein. Their identity with erythrocuprein. PMID- 4310832 TI - Studies on rates of abortive ternary complex formation of lactate dehydrogenase isozymes. PMID- 4310833 TI - Reductive titrations of iron-sulfur proteins containing two to four iron atoms. PMID- 4310834 TI - Monoxygenases. VII. Camphor ketolactonase I and the role of three protein components. PMID- 4310835 TI - Fructose 1,6-diphosphatase from rabbit liver. XII. Effect of substrate and adenosine monophosphate on the ionization of the tyrosyl residues. PMID- 4310836 TI - Enzymatic breakage of deoxyribonucleic acid. I. Purification and properties of endonuclease II from T4 phage-infected Escherichia coli. PMID- 4310837 TI - The differential inactivation of histidinol dehydrogenase from Salmonella typhimurium by sulfhydryl reagents. PMID- 4310838 TI - Surface antigens on interspecies hybrid cells. PMID- 4310839 TI - Differentiation of cross-reacting simian cytomegalovirus strains by late 19S rabbit neutralizing antibodies. PMID- 4310840 TI - The use of egg albumin conjugates for the purification of antibody. PMID- 4310841 TI - The relation of changes in sodium transport to protein-bound disulfide and sulfhydryl groups in the toad bladder epithelium. PMID- 4310842 TI - Norepinephrine turnover in brain and stress reactions in rats during paradoxical sleep deprivation. PMID- 4310843 TI - Further observations on hepatic drug metabolism in rats treated with a mixture of somatotropin, corticotropin and prolactin. PMID- 4310844 TI - Inhibition of estrogen-induced cyclic AMP elevation in rat uterus. II: By glucocorticoids. PMID- 4310845 TI - [Curiosities in medical history]. PMID- 4310846 TI - [Primary tumors at the bifurcation of the carotid artery. Contribution on the pathology, clinical aspects and case reports]. PMID- 4310847 TI - [Attempted use of the interference phenomenon for detection of probable human leukemia virus]. PMID- 4310848 TI - The behavioral effects of nicotinamide adenine dinucleotide in chronic schizophrenia. PMID- 4310849 TI - Longitudinal studies of the effect of monoamine oxidase inhibitors on sleep in man. PMID- 4310850 TI - [Changes in the levels of blood pressure during puberty in boys. II. Blood pressure and indices of somatic growth]. PMID- 4310851 TI - [Cytologic study of punctates in mammary gland diagnosis]. PMID- 4310852 TI - [Significance and effect of biological age on results of competitions among athletes during puberty]. PMID- 4310853 TI - [Myositis ossificans circumscripta. Histochemical and ultrastructural study of 1 case]. PMID- 4310854 TI - [Ultrastructure of "target fibers"]. PMID- 4310855 TI - [Thorotrast damage. Review and report of 3 cases]. PMID- 4310856 TI - Feline rhinovirus: characterization of an isolate. (brief report). PMID- 4310857 TI - The occurrence of virus particles in Rous hamster sarcoma. PMID- 4310858 TI - Comparative electron microscopic study of Rous sarcoma in Syrian hamster and rat. PMID- 4310859 TI - EEG effects of postoperative irradiation treatment of brain tumours. PMID- 4310860 TI - [Exeresis of a voluminous glomic tumor with extracorporeal circulation and deep hypothermia]. PMID- 4310861 TI - The uptake of nucleosides by cells in culture. I. Inhibition by heterologous nucleosides. PMID- 4310862 TI - The uptake of nucleosides by cells in culture. II. Inhibition by 2-mercapto-1 (beta-4-pyridethyl)benzimidazole. PMID- 4310863 TI - An RNA fraction from myeloblastosis virus having properties similar to transfer RNA. PMID- 4310864 TI - Deacylation of aminoacyl transfer RNA: comparison of enzyme preparations from different tissues of the rabbit. PMID- 4310865 TI - Regulatory significance of transfer RNA charging levels. I. Measurements of charging levels in livers of chow-fed rats, fasting rats, and rats fed balanced or imbalanced mixtures of amino acids. PMID- 4310866 TI - Effect of iron deficiency on nucleotide levels in Mycobacterium smegmatis. PMID- 4310867 TI - [Blocking action of the SV 40 virus repressor by a constitutive factor of cells tolerant for this virus]. PMID- 4310868 TI - [Infrastructure, relation, and distribution of viral and intraviral particles in generalizing mammary adenocarcinomas in mice]. PMID- 4310869 TI - [Clinical-experimental studies on the inhibitory effect of various corticoids]. PMID- 4310870 TI - Conduction velocity of optic nerve fibers innervating lateral geniculate body and superior colliculus in the rat. PMID- 4310872 TI - Effect of intake of copper, molybdenum and sulphate on copper metabolism in sheep. IV. Production of congenital and delayed swayback. PMID- 4310871 TI - Isolation and biological properties of secretory granules from rat anterior pituitary glands. AB - A method is described for the isolation of secretory granules from rat anterior pituitary glands. The method consists of differential and isopycnic gradient centrifugations, followed by filtration of the zones containing granules on Nuclepore filters to remove mitochondria. Highly purified granules were obtained as indicated by electron microscopy. Major parts of the thyrotropin (TSH) and adrenocorticotropin (ACTH) were recovered in a single fraction of granules as were follicle-stimulating (FSH) and luteinizing (LH) hormones. The somatotropin (STH) and prolactin (LTH) were recovered in separate granule fractions. The major parts of the six different hormones were associated with their respective granule fractions as shown by bioassays specific for each of the hormones. The diameters of granules in sections of intact rat pituitary glands and in isolated pellets were measured, and the means and ranges were in close agreement. These results contribute to the identification of the cell types which produce the different pituitary hormones. PMID- 4310873 TI - Immunofluorescence studies of parainfluenza 3 virus in the lungs of lambs. PMID- 4310874 TI - Cellular pathology of calves experimentally infected with bovine herpes mammillitis virus. PMID- 4310875 TI - Foreign-body reaction in the liver of a drug addict. PMID- 4310876 TI - Potential coenzyme inhibitors. 3. Some reactions of substituted nicotinamide and dihydronicotinamide derivatives. PMID- 4310877 TI - Synthesis and activity of some N-substituted alpha-(2-n-hexyl-4,5 dimethoxyphenyl) ethylamines against Entamoeba histolytica. PMID- 4310878 TI - Immunological responses to early and late intrauterine virus infections. PMID- 4310879 TI - Subclinical central nervous system disease of neonates: a prospective study of infants born with increased levels of IgM. PMID- 4310880 TI - Congenital cytomegalovirus infection: laboratory methods of detection. PMID- 4310881 TI - Statistical measurement of signal transmission in the central nervous system of the crayfish. PMID- 4310882 TI - A computer simulated model of a second order sensory neurone. PMID- 4310883 TI - The care of patients with long-term illness after their discharge from hospital. PMID- 4310884 TI - Pressor responsiveness to renin and angiotensin in renal hypertensive rats. PMID- 4310885 TI - [Adrenal reserve in children with normal and enlarged thymus]. PMID- 4310886 TI - [Results of therapy of Wilms tumors after 10 years of follow-up studies]. PMID- 4310887 TI - [Somatic development of children with cleft palate]. PMID- 4310888 TI - [Etiology of febrile exanthemas in a military environment and the hemagglutination inhibition test applied to the rubella virus]. PMID- 4310889 TI - Liver-function tests in primary cancer of the liver in the Bantu. PMID- 4310890 TI - Subcellular particles of human platelets. A biochemical and electron microscopic study with particular reference to the influence of fractionation techniques. PMID- 4310891 TI - [Pathology of calcareous emboli during calcified valvular diseases of the left side of the heart]. PMID- 4310892 TI - [A case of psychosomatic amenorrhea]. PMID- 4310893 TI - [Algodystrophy of the upper limb during radio-iodine treatment]. PMID- 4310894 TI - [Single plasmacytoma of the lung]. PMID- 4310895 TI - [Tuberculosis of post-menopausal endometrium. 2 cases with post-menopausal metrorrhagia]. PMID- 4310896 TI - [Leukemias and the alimentary tract]. PMID- 4310897 TI - [Prevention of thrombo-embolic complications (100 patients with hip surgery)]. PMID- 4310898 TI - [Tumors with endocrine activity producing amyloid. A morphological study in insulinomas and in calcitoninoma]. PMID- 4310899 TI - [Peculiarities of the regulatory effect of adenine nucleotides and other cofactors on the ability of mitochondria to bind exogenous NAD during ontogenesis]. PMID- 4310900 TI - [Effects of insulin and RNA on ribonucleoside di- and triphosphatases in liver nuclei and mitochondria of rabbits with alloxan-induced diabetes]. PMID- 4310901 TI - [Changes in the content of some phospholipids in the blood serum of rabbits during starvation]. PMID- 4310902 TI - [Use of paper chromatography and IR-spectroscopy in study of brain phosphoinositides]. PMID- 4310903 TI - [Effect of organic phosphate cholinesterase inhibitors on the content of gangliosides and other lipids in rabbit brain]. PMID- 4310904 TI - [Hydrolytic enzymes in a cell culture infected by smallpox vaccine virus]. PMID- 4310905 TI - [Problems of long-term aftercare following pacemaker implantation]. PMID- 4310906 TI - [Virological problems in hepatitis]. PMID- 4310907 TI - [Titration of the leukemogenic and immunogenic activity of Graffi mouse leukemia virus]. PMID- 4310908 TI - Oncogenicity of bovine papilloma virus. PMID- 4310909 TI - Factors in fusion of cells by HVJ. PMID- 4310910 TI - Conditional lethal mutants of animal viruses. PMID- 4310911 TI - Modifying health-care services for schizophrenic patients. PMID- 4310912 TI - [Mental disorders and infectious central nervous diseases in children]. PMID- 4310913 TI - Studies on angiotensin-induced glycosuria. PMID- 4310914 TI - Effect of aldosterone on angiotensin-induced glycosuria. PMID- 4310915 TI - Mechanism of angiotensin-induce glycosuria. PMID- 4310916 TI - Tonic and phasic events during sleep: psychological correlates and implications. PMID- 4310917 TI - The effect of reserpine and monoamine oxidase inhibitors on paradoxical sleep in the monkey. PMID- 4310918 TI - Morphine effects on human REM state, waking state and NREM sleep. PMID- 4310919 TI - Clinical and laboratory studies of ectopic humoral syndromes. PMID- 4310920 TI - [The histoenzymological characteristics of hydrolytic enzymes of the arterial wall at the initial stage of atherosclerosis]. PMID- 4310921 TI - Psychosocial factors modifying host resistance to experimental infections. PMID- 4310922 TI - Immunological parameters of the host-parasite relationship in neoplasia. PMID- 4310923 TI - Emotions and immunity. PMID- 4310924 TI - Sleep deprivation and EEG slow wave activity in chronic schizophrenia. PMID- 4310925 TI - [Determination of biogenic amines in animal and human skin as well as tumors by a thin-layer chromatographic method (Seiler technic). 3. 5-Hydroxytryptamine (serotonin)]. PMID- 4310926 TI - Activation in vitro of glucose-6-phosphatase, inorganic pyrophosphate-glucose phosphotransferase and related enzymes: relationship to microsomal membrane structure. PMID- 4310927 TI - Molecular structure in phospholipid essential to activate (Na+ K+ Mg2+)-dependent ATPase and (K+ Mg2+)-dependent phosphatase of bovine cerebral cortex. PMID- 4310928 TI - Alpha-adrenergic inhibition of Na+ transport: the interaction of vasopressin and 3',5'-AMP. PMID- 4310929 TI - Gel filtration of marker enzymes of plasma membrane and endoplasmic reticulum from rat liver. PMID- 4310930 TI - [Phospholipids of the cell nucleus and its membrane in rat liver. Composition and metabolism]. PMID- 4310931 TI - Reduced forms of the flavoprotein from egg-yolk. PMID- 4310932 TI - Use of rabbit cornea continuous cell line for the diagnosis of infectious bovine rhinotracheitis and equine rhinopneumonitis infections. PMID- 4310933 TI - The tricarboxylic acid cycle and associated reactions in Moniezia expansa (Cestoda). PMID- 4310934 TI - Feline viruses. XI. Isolation of a virus similar to a myxovirus from cats in which urolithiasis was experimentally induced. PMID- 4310935 TI - Platelet lipids (3). In vitro incorporation of 1-14C linoleic acid into lipid fractions of rabbit platelets. PMID- 4310936 TI - Preparation, derivation and partial characterization of organ-specific antigens from human brain. PMID- 4310937 TI - Susceptibility and resistance of various strains of Mycoplasma hyorhinis to antisera, polymyxins and low pH values. PMID- 4310938 TI - [Serological and immunological studies on Japanese encephalitis]. PMID- 4310939 TI - Vascular responses of the spleen to rapid haemorrhage in the anaesthetized cat. AB - 1. Splenic blood flow, splenic weight and arterial pressure were recorded in cats anaesthetized with sodium pentobarbitone. The mechanisms of the splenic contraction and vasoconstriction which followed rapid haemorrhage were investigated.2. When splenic arterial pressure was decreased progressively by mechanical occlusion of the coeliac artery, the decrease in splenic blood flow was proportional to the decrease in pressure; splenic weight did not change.3. After denervation of the spleen and adrenalectomy, haemorrhage resulted in a decrease in splenic flow which was similar to but slower than that in the innervated spleen; there was no splenic contraction. After splenic denervation, adrenalectomy and nephrectomy, haemorrhage caused a smaller decrease in flow but this response was still greater than that expected as a consequence of the reduced arterial pressure.4. Infusions of small doses of angiotensin caused splenic vasoconstriction with little change in splenic weight. Larger doses reduced both flow and weight.5. The splenic flow and weight responses to stimulation of the sympathetic nerves remained unimpaired when splenic blood flow was substantially reduced for 1-2 hr by haemorrhage.6. It is concluded that after a rapid haemorrhage, the splenic contraction is due only to activity of the splenic nerves and the adrenal medullae. The decrease in splenic flow is due to the reduction in arterial pressure, activity of the splenic nerves and the adrenal medullae, and the actions of angiotensin and some unidentified vasoconstrictor substance. PMID- 4310940 TI - Transmission from vasoconstrictor and vasodilator nerves to single arterial smooth muscle cells. PMID- 4310941 TI - Inhibitory post-synaptic potentials in the cerebral cortex. PMID- 4310942 TI - The iodide space in rabbit brain. AB - 1. The iodide space in rabbit brain varies greatly depending on the conditions under which it is determined.2. When (131)I(-) only is used the iodide space 4 hr after administration of the marker is of the order of 2%. The iodide content of the cerebrospinal fluid (c.s.f.) is about 1% of that of the serum.3. Depression of the active iodide transport by perchlorate increases the space to 8.2% and the iodide content of the c.s.f. to 26% of that of the serum.4. The active iodide transport can also be depressed by saturation with unlabelled iodide. Up to a serum iodide concentration of 5 mM the space determined after 5 hr remained constant at 2.7%. The iodide space grew when the serum iodide content was enhanced from 5 to 20 mM, to become constant at a value of 10.6% on further increase of the serum iodide (up to 50 mM). The iodide content of the c.s.f. increased in a similar manner as the space with the iodide concentration of the serum to about 1/3 of the serum concentration. The iodide space of the muscle was independent of the plasma iodide content.5. From 4 to 8 hr after administration of (131)I(-) alone or with unlabelled iodide (to a serum concentration of 15 mM) the iodide space remained relatively constant.6. When (131)I(-) was administered in the fluid with which the ventricles were perfused an iodide space of about 7% was attained after about 5 hr.7. In experiments in which (131)I(-) was administered intravenously and the sink action of the c.s.f. was eliminated by perfusion of the ventricles with a perfusate containing as much (131)I(-) as the plasma, the iodide space was 10.2%. When in addition active iodide transport was depressed by perchlorate the space increased to 16.8%.8. Intravenous administration of labelled and unlabelled iodide (to a serum concentration of 20 40 mM) and ventricle perfusion with the same concentration of (131)I(-) and unlabelled iodide as in the plasma yielded an iodide space of 20.8%. In similar experiments the iodide concentration of the perfusate was so adjusted that after 5 hr perfusion its iodide content hardly changed during the passage through the ventricles. Under these conditions the iodide concentration of the extracellular and perfusion fluids can be considered to be near equal. The iodide space computed on the basis of the iodide content of the outflowing fluid was 22.5%.9. The large iodide space could be equated with the extracellular space if the iodide remained extracellular. This seems to be the case in the muscle where the iodide space is similar to the inulin space.10. The large effects on the iodide space of perchlorate and saturation with unlabelled iodide in experiments in which the marker was administered intravenously and in the perfusate (7 and 8) suggests the presence of an active iodide transport from the brain extracellular fluid into the blood over the blood-brain barrier. PMID- 4310943 TI - Adenosine 3',5'-monophosphate (cyclic AMP) as the intracellular mediator of the action of secretin on the exocrine pancreas. PMID- 4310944 TI - Effect of barbiturates on 'quantal' synaptic transmission in spinal motoneurones. AB - 1. Monosynaptic excitatory post-synaptic potentials (EPSPs) produced in triceps surae motoneurones of the cat by stimulation of single afferent fibres in the muscle nerve were recorded with intracellular electrodes before and after the administration of thiopentone or pentobarbitone.2. The average amplitude of the ;unit' EPSP was 0.11-0.21 mV and remained unchanged after the administration of the barbiturates (10 mg/kg, I.V.).3. Mean quantum content (m) ranged from 1.9 to more than 5 before drug administration. The m was reduced by thiopentone (10 mg/kg, I.V.) and pentobarbitone (10 mg/kg, I.V.) by 23.1 and 24.7% respectively.4. The barbiturates, in the doses employed, produced no alterations in the input resistance of the motoneurone membrane or in the strength-duration relation obtained by passing depolarizing current pulses through the micro electrode.5. It is concluded that the action of thiopentone and pentobarbitone, in the doses used, is confined to the presynaptic nerve terminals and results in a reduction in the amount of transmitter released by afferent impulses. PMID- 4310945 TI - [Angiographic localization of islet cell tumors of the pancreas]. PMID- 4310946 TI - [The dermatologic case. 43. Abrikosoff's tumor]. PMID- 4310947 TI - [Surgical experiences in acoustic nerve with special reference to the translabyrinthine method]. PMID- 4310948 TI - [A case of adenocarcinoma which developed on the basis of papillary syringocystadenoma]. PMID- 4310949 TI - [Pathogenesis of arterial hypertension. Current trends and prospectives]. PMID- 4310950 TI - [Intestinal absorption of iron]. PMID- 4310952 TI - Alpha chloralose and nocturnal physiological patterns. PMID- 4310951 TI - [Phospholipid-splitting enzymes. 2]. PMID- 4310953 TI - [Differential diagnosis of acute leukemia by means of cytochemical methods]. PMID- 4310954 TI - [Electrotherapy of peripheral paralysis]. PMID- 4310955 TI - Pregnancy following treatment of mammary carcinoma. PMID- 4310956 TI - [Factors antagonistic to interferon extracts from tumors induced by murine sarcoma virus in hamsters]. PMID- 4310957 TI - [Neurilemmoma of the vagus nerve]. PMID- 4310958 TI - [Diagnosis and therapy of cutaneous glomus tumors]. PMID- 4310959 TI - [Partial replacement of the trachea. Emergency operation in stenosing cylindroma]. PMID- 4310960 TI - [Complement-fixing antibodies against the cytomegalovirus in children and adults]. PMID- 4310961 TI - [Hemangiomas]. PMID- 4310962 TI - [Vitamin D. New findings in the action mechanism of cholecalciferol]. PMID- 4310963 TI - [Hydrogen pathways in the mitochondrion of Saccharomyces carlsbergensis]. PMID- 4310964 TI - [Preparation of Neurospora crassa mitochondria, using a corundum disk-grinder and some of its properties]. PMID- 4310965 TI - [Cytochrome oxidase and associated with it a labelled protein from 14C-labelled mitochondria of Neurospora crassa]. PMID- 4310966 TI - [3',5'-cyclo-AMP as effector in the interconversion system of heart muscle pyruvate dehydrogenase]. PMID- 4310967 TI - [Structure of heat-treated poliovirus particles]. PMID- 4310968 TI - [Simple method for radioactive labelling of the membrane-specific polypeptide antibiotic polymyxin B: synthesis of the biologically active (1-14C)mono-N-acetyl derivative]. PMID- 4310969 TI - [Hydrolysis of complex lipids by lysosomal enzymes from rat liver]. PMID- 4310970 TI - [Effect of phenobarbital upon lysosomal enzymes]. PMID- 4310971 TI - [The identity of pepsitensin]. PMID- 4310972 TI - [Comparative studies on the antigenicity of ACTH-Z and synthetic ACTH]. PMID- 4310973 TI - [Anti SV-40 complement fixing antibodies in the serum of children]. PMID- 4310974 TI - [Evaluation of the occurrence of neoplastic diseases in children and the frequency of the different forms in case records of the Clinica Pediatrica in Genua in the period 1950-67]. PMID- 4310975 TI - [Microradiographic study of the skeleton in giants and dwarfs]. PMID- 4310976 TI - [Clinico-radiological peculiarities in precocious puberty in children]. PMID- 4310977 TI - [Some blood enzyme activity in hypervitaminosis D2 in children]. PMID- 4310978 TI - [Presence of hydrocyanic acid in cormophytes. 5. Cyanogenic compounds in Parietales and related families]. PMID- 4310979 TI - [Von Hippel-Lindau disease, cancer of the head of the pancreas, hypoglycemic islet cell adenoma. Comparison of tumor radiologic aspects of angiomatous nature revealed by selective arteriography]. PMID- 4310980 TI - [Ventriculo-cisternostomy under radioscopic control for obstructive hydrocephalus]. PMID- 4310981 TI - [Various aspects of the clinical picture and therapy of Sheehan's syndrome]. PMID- 4310982 TI - [Effect of blood corticosteroid level of pregnant rats on adrenocorticotropic function of the fetal pituitary gland]. PMID- 4310983 TI - Angiographic diagnosis of pancreatic disease. PMID- 4310984 TI - [Hemoptysis in Rendu-Osler-Weber's disease]. PMID- 4310985 TI - [Effect of silicagel desiccation on the sterility of donor's cornea in its experimental infection]. PMID- 4310986 TI - [Effects of various disease conditions of the upper extremity on the peripheral circulation, with special reference to photoelectric plethysmography of the finger tip]. PMID- 4310987 TI - [Enzyme activity of the synovial membrane and fluid]. PMID- 4310988 TI - [Immuno-epidemiology of acute infectious diseases during infancy]. PMID- 4310989 TI - Determination of phosphate and phosphomonoesterases in biologic materials. PMID- 4310990 TI - A single-oven gas chromatograph with a simple, all-quartz, flame ionization detector. PMID- 4310991 TI - Evaluation of electron spin resonance for quantitative determinations of gadolinium, chromium, iron, copper and manganese. PMID- 4310992 TI - Effects of hypnotics on sleep patterns, dreaming, and mood state: Laboratory and home studies. PMID- 4310993 TI - Sleep of the body. PMID- 4310994 TI - Effect of antidepressant drugs on sleeping and dreaming. 3. On the depressed patient. PMID- 4310995 TI - The sleep rhythms of subcortical nuclei: some observatis in man. PMID- 4310996 TI - Gas-chromatographic estimation of urinary vanillylmandelic acid after transformation to vanillin methoxime trimethylsilyl ether. PMID- 4310997 TI - [Ocular observations in generalized cytomegalic inclusion disease]. PMID- 4310998 TI - Effect of morphine on cholinergic receptors. PMID- 4310999 TI - Studies on the effect of diazepam (Valium) on neuromuscular transmission in skeletal muscles. PMID- 4311000 TI - Chemical composition of some bovine nephroliths with special reference to silica nephroliths. PMID- 4311001 TI - Malignant head catarrah (?). A case report. PMID- 4311002 TI - [Result of Japanese encephalitis surveillance in 1967]. PMID- 4311003 TI - A comparison of two methods for the separate estimation of 11-deoxy and 11 oxygenated 17-hydroxycorticosteroids in urine. PMID- 4311004 TI - Experimental endogenous lipid pneumonia and silicosis. PMID- 4311005 TI - Light- and electron-microscope studies on the granular cell myoblastoma of the tongue. PMID- 4311006 TI - Aging of aortic smooth muscle cells in rats and rabbits. A morphologic and biochemical study. PMID- 4311007 TI - The effect of portacaval transposition on radiation nephritis-induced hypertension in the dog. PMID- 4311008 TI - [Clinicopathological conference. No. 153]. PMID- 4311009 TI - Breast cancer after prophylactic subcutaneous mastectomies and reconstructionwith silastic prostheses. PMID- 4311010 TI - Auriculotemporal syndrome (Frey's syndrome), secondary to fracture of the mandibular condyle. PMID- 4311011 TI - Mouse leukemia virus activation by chemical carcinogens. AB - The induction of lymphomas in C57BL mice by methylcholanthrene, urethan, or diethylnitrosamine was accompanied by the development of murine leukemia viral antigen in most of the lymphoid tumors. The cell-free transmission of lymphomas induced by methylcholanthrene and the development of antibody to murine leukemia virus prior to the detection of overt lymphoma in these mice suggest that unmasking of a latent leukemia virus is an indigenous actuating cause of the lymphomas. PMID- 4311012 TI - Fine structure and biochemical properties of purified cytochrome oxidase. PMID- 4311013 TI - Paralytic poliomyelitis in an unimmunized child. Apparent result of a vaccine derived poliovirus. PMID- 4311014 TI - Neonatal herpetic infection. Report of two premature infants treated with systemic use of idoxuridine. PMID- 4311015 TI - Sino-aortic reflexes and arterial pH, PO2, and PCO2 in wakefulness and sleep. PMID- 4311016 TI - Serotonin mediation of circadian periodicity of plasma 17-hydroxycorticosteroids. PMID- 4311017 TI - Intrarenal blood flow and PAH extraction during angiotensin infusion. PMID- 4311018 TI - Location of synaptic connections in canine sympathetic cardiac innervation. PMID- 4311019 TI - Electrophysiological properties of Limulus heart and effect of drugs. PMID- 4311020 TI - Release of infectious canine hepatitis virus. PMID- 4311021 TI - Pathogenesis of canine herpesvirus in specific-pathogen-free dogs: 5- to 12-week old pups. PMID- 4311022 TI - Pathogenesis of bovine mamillitis virus infection in cattle. PMID- 4311023 TI - Intratemporal facial palsy. PMID- 4311024 TI - Localization of glycosyl transferase activities in a Golgi apparatus-rich fraction isolated from rat liver. PMID- 4311025 TI - The incorporation of p-hydroxybenzoic acid and isopentenyl pyrophphate into ubiquinone precursors by cell-free preparations of rat tissues. PMID- 4311026 TI - On the phosphorescence of collagen. PMID- 4311027 TI - Equilibrium and kinetic studies on the reversible dissociation of yeast enolase by neutral salts. PMID- 4311028 TI - Isolation of 17-alpha-estradiol 17-beta-D-glucopyranoside from rabbit urine, and its synthesis and characterization. PMID- 4311029 TI - Interactions of lipids with a membrane structural protein from myelin. PMID- 4311030 TI - Studies on lysyl transfer ribonucleic acid synthetase from Escherichia coli. PMID- 4311031 TI - N6-(delta-2-isopentenyl) adenosine. Biosynthesis in transfer ribonucleic acid in vitro. PMID- 4311032 TI - Dinitrophenylation and thiolysis in the reversible labeling of a cysteine residue associated with the nicotinamide-adenine dinucleotide site of rabbit muscle glyceraldehyde 3-phosphate dehydrogenase. PMID- 4311033 TI - Spin labeling of vitamin B 12. PMID- 4311034 TI - The reaction of L-serine O-sulfate with aspartate aminotransferase. PMID- 4311035 TI - Lipid composition of synaptic plasma membranes isolated from rat brain by zonal centrifugation. PMID- 4311036 TI - Structure of succinoglucan, and exocellular acidic polysaccharide of Alcaligenes faecalis var. myxogenes. PMID- 4311037 TI - The significance of intermediary plateau regions in enzyme saturation curves. PMID- 4311039 TI - Chromatography and radioimmunoassay of angiotensin II and metabolites in blood. PMID- 4311038 TI - Phosphorescence and energy transfer in enzymes. PMID- 4311040 TI - Electron spin resonance study on single crystals of haemoglobin M Kankakee. PMID- 4311042 TI - Electron spin resonance study of the transition metal-binding site of concanavalin A. PMID- 4311041 TI - Properties of hemoglobin M, Milwaukee-I variant and its unique characteristic. PMID- 4311043 TI - Sclerosing injections for esophageal varices. PMID- 4311044 TI - [In vivo synaptic transmission in the smooth muscle cells of the guinea-pig vas deferens]. PMID- 4311045 TI - The effects of alpha amylase on collagen-proteoglycans and collagen-glycoprotein complexes in connective tissue matrices. PMID- 4311046 TI - Effect of electrical stimulation of the medial mid-brain reticular formation and administration of ACTH on the plasma electrolytes. PMID- 4311047 TI - Cardiovascular responses to hypertension and hypotension in dogs with denervated hearts. PMID- 4311048 TI - Hereditary infections with mammary tumor viruses in mice. PMID- 4311049 TI - Hepatoma and renal tubule adenoma in rats fed aflatoxin and cyclopropenoid fatty acids. PMID- 4311050 TI - Pituitary mammotropic tumor in rats: evidence for a dosage effect on organ weight and liver drug metabolism. PMID- 4311051 TI - High-yield isolation of mouse mammary tumor virus. PMID- 4311052 TI - Antigenic and oncogenic properies of a cell line derived frm a hamster brain tumor induced by simian adenovirus 7. PMID- 4311053 TI - An electron microscope study of glycogen formation in novikoff ascites-hepatoma cells. PMID- 4311054 TI - Pathogenesis of Bartter's syndrome. PMID- 4311055 TI - So-called Bartter's syndrome. PMID- 4311056 TI - Transient changes in EEG sleep patterns of married good sleepers: the effects of altering sleeping arrangement. PMID- 4311057 TI - Dreams of subjects with loss of memory for recent events. PMID- 4311058 TI - Community nursing services as perceived by posthospatalized patients. PMID- 4311059 TI - Potentiation of venoconstriction by alpha,alpha'-bis (dimethylammoniumacetaldehyde diethylacetal)-p,p'-diacetylbiphenyl dibromide, DMAE. PMID- 4311060 TI - Pancreatic islet cell carcinoma with hyperinsulinism and probable, ectopic ACTH MSH secretion. PMID- 4311061 TI - The nature of the enzymically catalysed binding of glucose to the protein coat of Colpoda steinii cysts. PMID- 4311062 TI - An automatic apparatus for the study of enzyme kinetics. AB - A continuous-flow apparatus is described for automatically plotting substrate saturation curves, and is suitable for use with a variety of enzymes. A linear concentration gradient of the variable substrate is combined with a fixed proportion of the other substrates and the enzyme, and after passing through a reaction coil the product concentrations are measured spectrophotometrically. Use of a 4cm. flow cell and modified spectrophotometer permits accurate measurement of NADH concentration in the region of 0.1mum. Precise control over reaction times and substrate concentration is achieved by using power-driven syringes with an integral mixer. Specimen results are given for yeast alcohol dehydrogenase. PMID- 4311063 TI - The enzymic hydroxylation of protocollagen models. AB - 1. Synthetic polymers of l-prolyl-l-prolylglycine of defined chain length, (Pro Pro-Gly)(n), were found to be substrates for the enzyme protocollagen-proline hydroxylase, with optimum chain length n=5. Boiling the polymer (Pro-Pro-Gly)(15) increased its activity as a substrate but had no effect on (Pro-Pro-Gly)(5). 2. Protection of both or one of the N- and C-terminal groups made (Pro-Pro-Gly)(3) a better substrate, and collagenase digestion of hydroxylated tert.-pentyloxy carbonyl-(Pro-Pro-Gly)(3) benzyl ester indicated that the central prolyl residues were the major points of hydroxylation. 3. The results suggest that the long chain peptides are optimum substrates but that a triple-stranded structure is inhibitory for hydroxylation. PMID- 4311065 TI - The regulation of L-asparaginase activity in rats and mice. Effects of normal and malignant growth, of sex and of dietary changes. AB - 1. The activity of l-asparaginase was very low in the liver of newborn rats and mice, and increased within a few days of birth. 2. In rats, but not in mice, the enzyme activity was higher in females than in males, was enhanced by administration of oestradiol, and was decreased by gonadectomy. 3. The enzyme activity decreased in mice starved or fed on a low-protein diet; in rats it was enhanced by starvation, by feeding them on a high-protein diet, or by administration of l-asparagine. 4. The asparaginase activity was decreased in regenerating liver, and was almost absent in the Morris hepatoma 5123. PMID- 4311064 TI - Properties of the inactive ribosomal components in rat liver and hepatoma. AB - 1. The relative concentrations of the inactive ribosomal components were compared in normal and regenerating rat liver and in two transplantable rat hepatomas (hepatomas 7800 and 5123D). 2. The size of the ribosomal-subunit pools in normal liver was not significantly affected by partial hepatectomy or neoplasia although, as shown previously, significant changes do occur in the monomer pool. 3. Further, the subunit pools in both liver and hepatoma were not significantly influenced by several treatments that caused dramatic changes in the size of the ribosomal monomer (and dimer) pools. 4. The high concentration of inactive monomers and dimers in the hepatomas appears to arise from limitations at the translational level, since they can be incorporated into pre-existing polyribosomes under the influence of cycloheximide. PMID- 4311066 TI - Purification and characterization of bovine enteroviruses. PMID- 4311067 TI - Composition of the phospholipid fraction of Corynebacterium diphtheriae. PMID- 4311068 TI - [Angiographic characteristics of metastatic brain tumor]. PMID- 4311069 TI - The effect of triiodothyronine on cyclic AMP, phosphorylase, and adenyl cyclase in rat heart. PMID- 4311070 TI - Nucleotide sequences from specific areas of the 16S and 23S ribosomal RNAs of E. coli. PMID- 4311071 TI - Labeling of alpha-P of nucleoside triphosphates by in vivo incorporation of 32P in rat liver. PMID- 4311072 TI - [Electron spin resonance investigation of hemin-mercaptan complexes]. PMID- 4311073 TI - Age-correlated changes in lysosomal enzyme activities: an index of ageing? PMID- 4311074 TI - Comparison of chemically induced and virus-induced chromosome aberrations. PMID- 4311075 TI - Vesicular stomatitis virus autointerference. PMID- 4311076 TI - The herpesvirion and its precursors made in productively and in abortively infected cells. PMID- 4311077 TI - Heterogeneous DNof simian virus 40. PMID- 4311078 TI - Studies on lactic dehydrogenase in health and in diseases. PMID- 4311079 TI - Cytogenetic and nuclear studies on A9 and B82 cells fused together by sendai virus: the early phase. PMID- 4311080 TI - Primary aldosteronism in a hypertensive acromegalic patient. PMID- 4311081 TI - Occurrence of a virilizing syndrome with 21-hydroxylase deficiency after pregnancy. PMID- 4311082 TI - Application of a radioimmunoassay for angiotensin I to the physiologic measurements of plasma renin activity in normal human subjects. PMID- 4311083 TI - [Pneumoconiosis and pulmonary tuberculosis]. PMID- 4311084 TI - [Approach to the determination of normal values of 17-hydroxycorticosteroids (Porter-Silber chromogen) in human urine]. PMID- 4311085 TI - [Simplified identification of Clostridium perfringens-antitoxin disc method]. PMID- 4311086 TI - Effects of hydrocortisone on the metabolism of muscular lipids. PMID- 4311087 TI - Studies on morphological precursors of the mouse hepatoma induced with o aminoazotoluene. II. Sequence to the development of hepatoma and its gradation with strain SL mice. PMID- 4311088 TI - Cell transformation by polyoma virus and SV40. PMID- 4311089 TI - Vasopressin test in tumours of the sellar region. PMID- 4311090 TI - Cottonseed meal and tumors. PMID- 4311091 TI - Advances in the treatment of respiratory disorders. PMID- 4311092 TI - Advances in the treatment of endocrine disorders. PMID- 4311093 TI - [Current progress in the study of vitamin D--discovery of active vitamin D]. PMID- 4311094 TI - Enzyme histochemical studies of senile plaques and the plaque-like degeneration of arteries and capillaries (Scholz). PMID- 4311095 TI - Study of dreams by using "REMP-awakening technique" psychophysiological study of dreams in normal subjects. 1. PMID- 4311096 TI - Psychophysiological study on the dreams of chronic schizophrenics--studies on the dreams of psychotics. I. PMID- 4311097 TI - [Specificity of chemotherapy in various fields--internal medicine]. PMID- 4311098 TI - [Nephrotoxicity of antimicrobial agents]. PMID- 4311099 TI - [2 cases of ACTH producing lung tumor]. PMID- 4311100 TI - Variations in REM dreaming and the effectiveness of behavior in group therapy. PMID- 4311101 TI - [Clinical aspects of supratentorial vestibular pathology. Case records of 54 cases]. PMID- 4311102 TI - Dreaming and nitrous oxide. PMID- 4311103 TI - Drug-induced changes in blood pressure as recorded by direct and indirect methods. PMID- 4311104 TI - Fructose 1,6-diphosphatase from rabbit liver. 13. The number of Mn++ binding sites measured with 54Mn++. PMID- 4311105 TI - Role of multiple binding sites in the inhibition of NADH oxidase by piericidin and rotenone. PMID- 4311106 TI - The hydrolysis of phosphoenol pyruvate catalyzed by rabbit liver fructose-1,6 diphosphatase. PMID- 4311107 TI - Inhibition by viomycin of cell-free protein synthesis in sensitive and resistant strains of Rhizobium meliloti. PMID- 4311108 TI - Hyperparathyroidism associated with malignant tumors of nonparathyroid origin. PMID- 4311109 TI - Paget's disease of the male breast. PMID- 4311110 TI - Enzyme histochemical study of primary hepatic carcinoma in Thailand. PMID- 4311111 TI - Hepatoblastoma in infant sisters. PMID- 4311112 TI - Bronchiolar carcinoma: a valid clinicopathologic entity? A study of 30 cases. PMID- 4311113 TI - Endolymphatic radiotherapy. A comparison of radiogold and radioiodine against the VX2 tumor in the rabbit. PMID- 4311114 TI - Comparative ultrastructure of atypical ductal hyperplasia, intraductal carcinoma, and infiltrating ductal carcinoma of the breast. PMID- 4311115 TI - Early phases in the development of breast cancer. PMID- 4311116 TI - Prognosis of breast cancer based on pathologic type. PMID- 4311117 TI - Breast xeroradiography. PMID- 4311118 TI - Viruses as possible etiologic factors in human breast cancer. PMID- 4311119 TI - Studies of human milk in relation to the possible viral etiology of breast cancer. PMID- 4311120 TI - A new approach to mammary tumorigenesis in rodents. PMID- 4311121 TI - Mammary carcinoma. A discussion of therapeutic methods. PMID- 4311122 TI - [Infrared thermometry in the differential diagnosis of breast neoplasms]. PMID- 4311123 TI - [A case of poisoning due to cutaneous application of an antifungal agent]. PMID- 4311124 TI - [Some findings on corticotropinic function in acromegaly: effects of hypophysial block with triamcinolone on the nyctohemeral rhythm of plasma cortisol]. PMID- 4311125 TI - [Functional evaluation of the adrenal cortex in acromegalic patients: test of fast stimulation with synthetic ACTH (beta 1-24 corticotropin)]. PMID- 4311126 TI - The effect of density-delayed pupation on cytochrome oxidase activity in Drosophila melanogaster. PMID- 4311127 TI - Histochemical study of oxidative and hydrolytic enzymes in the abnormal human parathyroid. PMID- 4311128 TI - Ataxia-telangiectasia with gastric adenocarcinoma. PMID- 4311129 TI - Morphological studies on the peripheral small arteries of spontaneously hypertensive rats. PMID- 4311130 TI - Hyperbaric oxygen in gas gangrene. PMID- 4311131 TI - The function of the adrenal glands during prolonged corticosteroid therapy. PMID- 4311132 TI - A study of the effect of corticotrophin on skeletal maturation and linear growth on six patients with severe asthma. PMID- 4311133 TI - The effects of corticosteroid and ACTH therapy on growth and on the hypothalamic pituitary adrenal axis of children. PMID- 4311134 TI - Physiology of the adrenal cortex in childhood. PMID- 4311135 TI - [The use of desiccated cornea in eye burns]. PMID- 4311136 TI - Fine structure of smooth muscle and neuromuscular junctions in the foot of Helix aspersa. PMID- 4311137 TI - [Approach on removal of juvenile angiofibroma from the palatoalar fossa and retromandibular region]. PMID- 4311138 TI - Treatment of acute ischemic pain in the leg by induced hypertension. PMID- 4311139 TI - Histoenzymology of the developing human hippocampus. PMID- 4311140 TI - Aseptic osseous necrosis and corticosteroid therapy. PMID- 4311141 TI - Renal disease in juvenile rheumatoid arthritis. PMID- 4311142 TI - [Gonadal dysgenesis with karyotype 46 XY]. PMID- 4311143 TI - [Blood gonadotrophins in the normal child and during puberty]. PMID- 4311144 TI - Binding and properties of NAD+ in glyceraldehydephosphate dehydrogenase from lobster-tail muscle. PMID- 4311145 TI - Function and role of NAD+ in mechanism of action of rabbit-muscle glyceraldehydephosphate dehydrogenase. PMID- 4311146 TI - Regulatory properties of primate sperm phosphofructokinase. PMID- 4311147 TI - Cyclic 3',5'-nucleotide phosphodiesterase. Preparation of a partially inactive enzyme and its subsequent stimulation by snake venom. PMID- 4311148 TI - Enzymatic hydrolysis of adenosine 3'-5'-cyclic phosphorothioate. PMID- 4311149 TI - The renin-like enzyme of rabbit uterus. PMID- 4311150 TI - Stabilization of deoxycytidylate deaminase from mammalian tissues. PMID- 4311151 TI - Intermediates in the hydrolysis of ATP by human alkaline phosphatase. PMID- 4311152 TI - Lysosomal localization of sphingomyelinase in rat liver. PMID- 4311153 TI - [Intrauterine infections due to cytomegalic virus]. PMID- 4311154 TI - [Research on calcium-phosphorus metabolism in viral hepatitis]. PMID- 4311155 TI - [Surgical treatment of pituitary adenoma]. PMID- 4311156 TI - [Etiology of "viral" diarrhea in early childhood]. PMID- 4311157 TI - [Adrenal cortex function in patients with lesions of the limbic system structures]. PMID- 4311158 TI - [Role of the pituitary gland in the regulation of transcortin binding capacity in man]. PMID- 4311159 TI - [Regulation of the dehydroepiandrosterone secretion by the adrenal cortex]. PMID- 4311160 TI - [Value of some auxiliary methods in the diagnosis of hyperparathyroidism]. PMID- 4311161 TI - [Glucocorticoid function of the adrenal glands in dogs and guinea pigs following administration of some dichlordiphenyldichlorethane isomers]. PMID- 4311162 TI - [Granular cell myoblastoma]. PMID- 4311163 TI - The oxidation of neuraminyl groups: a new protein-coupling agent. PMID- 4311164 TI - [Intensity of renewal of phospholipid phosphorus in pigeon myocardium]. PMID- 4311165 TI - [Mechanism of the effect of physical work on cholesterol metabolism. Effect of prolonged administration of pangamic acid (vitamin B 15) on muscle chemism]. PMID- 4311166 TI - [Rare site for a glomus tumor]. PMID- 4311167 TI - [Experimental-clinical evaluation of non-citrated blood prepared with a new sorbent]. PMID- 4311168 TI - [Direct cervical lymphangioadenography in oncologic patients]. PMID- 4311169 TI - [Lymphangiography in congenital elephantiasis of the extremities in children]. PMID- 4311170 TI - [The method of silicodesication of the donor cornea and its use in lamellar keratoplasty]. PMID- 4311171 TI - [Synovial sarcoma of the inguinal region]. PMID- 4311172 TI - [Surgical treatment of chemodectomas of the carotid gland]. PMID- 4311173 TI - [Features of the utilization of parenterally administered labelled enzymes in tumor-affected bodies of animals]. PMID- 4311174 TI - [A histochemical study of the activity of various enzymes in induced tumors of the kidneys in animals]. PMID- 4311175 TI - [Determination of nucleic acids in cells infected by Rous sarcoma virus by means of ultraviolet microscopy]. PMID- 4311176 TI - Incorporation of alanine-14C and leucine-14C into protein of Escherichia coli under the influence of insulin. PMID- 4311177 TI - Isolation and partial characterization of the exocellular polysaccharides of Penicillium charlesii. II. The occurrence of phosphate groups in high molecular weight polysaccharides. PMID- 4311178 TI - Molecular size and feedback-regulation characteristics of bacterial asartate transcarbamulases. PMID- 4311179 TI - Purification and properties of acyl phosphatase from human erythrocytes. PMID- 4311180 TI - The hydroxylamine reductase of mitochondria. PMID- 4311181 TI - Stabilit of the glycosidic bond of S-adenosylsulfonium compounds toward acid. PMID- 4311182 TI - Glutamine synthetase of Neurospora crassa. Inactivation by urea and protection by some substrates and allosteric effectors. PMID- 4311183 TI - Metabolic activities of mechanically and enzymatically prepared rat liver cells. PMID- 4311184 TI - Methionine biosynthesis in Ochromonas malhamensis. PMID- 4311185 TI - Nasal mucosal absorption of tetracosactrin as indicated by rise in plasma fluorogenic corticosteroids. AB - Tetracosactrin has been administered to six healthy dexamethasone-suppressed subjects by nasal insufflation. The pronounced increase of the plasma fluorogenic corticosteroids suggests that the peptide is well absorbed by this route. PMID- 4311186 TI - Lymphoma and glandular fever. PMID- 4311187 TI - Intermittent corticotrophin treatment: ventilatory tests in asthmatic subjects. AB - Ventilatory tests (F.E.V.(1)/F.V.C.) have been studied in 16 asthmatic subjects during intermittent administration of corticotrophin, and the responses correlated with the plasma cortisol levels. The improvement in respiratory function was found to last for a longer period than the enhanced adrenocortical activity. PMID- 4311188 TI - Influence of amphetamines on plasma corticosteroid and growth hormone levels in man. AB - Plasma fluorogenic corticosteroid and immunoreactive growth hormone levels rose significantly after the intravenous administration of methylamphetamine to healthy young men at various times of the day. The rise in corticosteroids was most pronounced in the evening and was accompanied by an increase in circulating levels of immunoreactive corticotrophin. Oral dexamphetamine also resulted in significant rises in plasma corticosteroids but not in growth hormone. These hormonal changes were accompanied by evidence of mild central stimulation. Though they may be part of an associated and non-specific response, it is more likely that they represent specific effects of amphetamines on centres in the hypothalamus or midbrain controlling secretion of corticotrophin and growth hormone releasing factors. PMID- 4311189 TI - Comparison of depot tetracosactrin and corticotrophin gel. AB - Depot tetracosactrin has been compared with corticotrophin gel in 12 inpatients of a rheumatic diseases unit Every patient received one subcutaneous infection each of the synthetic and the animal preparation, with serial measurements of plasma 11-hydroxycorticosteroids, 12-hourly urinary 11-hydroxycorticosteroids, and 17-oxogenic steroids. The duration of action of the depot tetracosactrin was virtually twice that of corticotrophin gel, the dose relationship being about 0.25 mg. of depot tetracosactrin to 50 units of gel. Local reaction to the injection of depot tetracosactrin was relatively frequent. PMID- 4311190 TI - Delay of hormonally induced diabetes by amino-glutethimide and metyrapone in partially pancreatectomized rats bearing transplantable pituitary tumors. Concomitant failure to prevent splanchnomegaly. PMID- 4311191 TI - Independent variation of glucagon and epinephrine responsive components of hepatic adenyl cyclase as a function of age, sex and steroid hormones. PMID- 4311192 TI - An acute effect of estradiol on steroid hydroxylation by the rat adrenal. PMID- 4311193 TI - Serotonin inhibition of in vitro insulin release from golden hamster pancreas. PMID- 4311194 TI - Reactions involved in the conversion of ornithine to proline in Clostridia. AB - An enzyme system which converts ornithine to proline was partially purified from extracts of cells of Clostridium botulinum and of Clostridium PA 3670 by fractionation with ammonium sulfate and by dialysis in the presence of 0.01 m ornithine. Nicotinamide adenine dinucleotide (NAD) was the only cofactor required for maximal activity of the partially purified system. A possible intermediate in the conversion was accumulated when a high concentration of proline was used as substrate and the NAD was maintained in the oxidized state by adding lactic dehydrogenase. Small but significant amounts of this or a similar compound were trapped with either ornithine or proline as substrate when o-aminobenzaldehyde was added to reaction mixtures. The accumulation of the o-aminobenzaldehyde reaction product was NAD-dependent with both substrates. The compound accumulated from proline was identified as Delta(1)-pyrroline-5-carboxylic acid on the basis of the melting point of the 2,4-dinitrophenylhydrazone, and by paper chromatography of the reaction product formed with o-aminobenzaldehyde. Also, extracts of C. botulinum cells oxidized reduced NAD (NADH) in the presence of the product from proline or in the presence of Delta(1)-pyrroline-5-carboxylic acid, but did not do so in the presence of the other possible intermediate, Delta(1) pyrroline-2-carboxylic acid. (14)C-Delta(1)-pyrroline-5-carboxylic acid was reduced to (14)C-proline by these extracts in the presence of NADH. These data indicate that the conversion of ornithine to proline by C. botulinum and Clostridium PA 3679 cells involves an oxidation of ornithine to glutamic-gamma semialdehyde which undergoes ring closure to Delta(1)-pyrroline-5-carboxylic acid. The latter compound is then reduced to proline. PMID- 4311195 TI - Phosphorylation and the reduced nicotinamide adenine dinucleotide oxidase reaction in Streptococcus agalactiae. AB - Cell-free extracts from aerobically grown Streptococcus agalactiae cells possess a reduced nicotinamide adenine dinucleotide (NADH) oxidase which is linked to oxygen. It is inhibited by cyanide, although cytochromes evidently are not involved. Adenosine triphosphate (ATP) formation occurs during the reaction, but 66 to 75% of the total ATP is formed nonoxidatively. The remaining 25 to 35% of the ATP formation is related to the oxidation of NADH. The formation of ATP in the oxidative reaction can be prevented by excluding oxygen or adding cyanide to prevent NADH oxidation. It can also be prevented by adding methylene blue or pyruvate, which bypasses electron transport to oxygen, but does not interfere with NADH oxidation. Potential sources of ATP, such as glycolysis, the pyruvate oxidase reaction, or the oxidative pentose cycle, are not present, and the high nonoxidative ATP formation is ascribed to the adenylate kinase reaction. The reaction requires adenosine diphosphate (ADP) as a phosphate acceptor. NADH oxidation is independent of ADP. Antimycin A, amytal, and 2,4-dinitrophenol decreased, but did not prevent, oxidative formation of ATP. P:O ratios ranged from 0.15 to 0.25. All of the oxidative activity was in the soluble portion of the cell-free extracts. PMID- 4311196 TI - Effects of some hormonal and other factors on the excretion of guanosine 3',5' monophosphate and adenosine 3',5'-monophosphate in rat urine. PMID- 4311197 TI - Determination of guanosine 3',5'-monophosphate in tissues and of guanyl cyclase in rat intestine. PMID- 4311198 TI - Cyclic nucleotide-dependent protein kinases. 3. Purification and properties of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain. PMID- 4311199 TI - Composition and synthesis of gangliosides in rat hepatocyte and hepatoma cell lines. PMID- 4311201 TI - Idoxuridine in herpesvirus encephalitis. PMID- 4311200 TI - Herpesvirus hominis encephalitis in Michigan. Report of thirteen cases, including six treated with idoxuridine. PMID- 4311202 TI - Cytomegalovirus infection in pregnancy. PMID- 4311203 TI - Thorium dioxide angiography causing bile duct carcinoma; a case report with radiological studies. PMID- 4311204 TI - [The course of acute respiratory disease in early childhood depending on the causative agent]. PMID- 4311205 TI - [Pathogenetic bases of the use of prednisolone in the treatment of children with Botkin's disease]. PMID- 4311206 TI - Growth of herpes simplex virus in adult human skin organ cultures. PMID- 4311207 TI - Mediation of the mitogenic action of growth hormone by adenosine 3'5' monophosphate (cyclic AMP). PMID- 4311208 TI - Viability of foot-and-mouth disease virus in oil emulsions. PMID- 4311209 TI - Effect of antithymocyte serum on herpesvirus hominis (type 1) infection in adult mice. PMID- 4311210 TI - Yaba tumor virus. II. Studies on inactivation and reactivation. PMID- 4311211 TI - Evidence for the susceptibility of primary fetal mouse cells in culture to coxsackievirus A13. PMID- 4311212 TI - Inducers of interferon and host resistance. VII. Antiviral efficacy of double stranded RNA of natural origin. PMID- 4311213 TI - Induction of the interferon mechanism by single-stranded RNA: potentiation by polybasic substances. PMID- 4311214 TI - Growth of ultraviolet-damaged herpesvirus in xeroderma pigemntosum. PMID- 4311215 TI - Potassium ions asymmetrically activate erythrocyte membrane phosphatase. AB - In Reconstituted ghosts of human red cells, the cell membrane phosphatase is activated by external, but not by internal, potassium. This finding is consistent with the possible participation of the membrane system responsible for cation transport. PMID- 4311216 TI - Simian virus 40 in polio vaccine: follow-up of newborn recipients. AB - Soon after birth, when susceptibility to carcinogens should be enhanced, a group of children received oral polio vaccine which was later found to contain significant amounts of simian virus 40. Eight years after the incident, no cancer deaths have been observed among the vaccinated children, but continued surveillance is needed before concluding that simian virus 40 is innocuous to man. PMID- 4311217 TI - [Metabolism of nicotinamide coenzymes following total-body irradiation. I. Catabolism of NAD and excretion of its metabolites]. PMID- 4311218 TI - [Surgical stress and the function of the adrenal cotex--acute adrenal insufficiency in surgery]. PMID- 4311219 TI - Studies on ACTH-binding antibodies: characterization of immunological specificities. PMID- 4311220 TI - Necrotizing infectious enteritis in piglets, caused by Clostridium perfringens type C. 3. Pathological changes. PMID- 4311221 TI - Necrotizing infectious enteritis in piglets, caused by Clostridium perfringens type C. IV. Bacteriological diagnosis. PMID- 4311222 TI - Individual differences in the frequency of hippocampal theta activity in relation to the nonspecific (constitutional) excitability level in rats. PMID- 4311223 TI - The relation between the duration of quiet and paradoxical sleep in infants. PMID- 4311224 TI - Congestive heart failure: biochemical and physiologic observations. PMID- 4311225 TI - Purification of complement-fixing antigens of Rickettsia orientalis by ether extraction. PMID- 4311226 TI - [Immunological research on L-alpha1-fetal protein or fetuin in primary tumors of the liver and malignant teratomas of the child (18 positive cases)]. PMID- 4311227 TI - Varicella-Zoster encephalomyelitis. A morphologic and virologic study. PMID- 4311228 TI - Effects of cold injury on six enzymes in rat brain. PMID- 4311229 TI - Experimental herpes simplex uveitis. The isolation of herpesvirus in an iris organ culture system. PMID- 4311230 TI - A new resin system restorative designed for universal anterior and posterior applications: report of a clinical study. PMID- 4311231 TI - Levels of glutathione in schizophrenic patients. (A biochemical-clinical study). PMID- 4311232 TI - [Interrelationship between microvibration and autonomic nervous and endocrine environment of menstrual disorder]. PMID- 4311233 TI - [In vitro experimental studies on the renin-angiotensin system and corticosteroid biosynthesis in the rats]. PMID- 4311234 TI - [The radiotherapy of the intraocular melanoblastoma as a biological model at the amelanotic melanoblastoma 3 Fortner of the golden hamster]. PMID- 4311235 TI - Bile duct carcinoma in a goat, with metastasis in the lungs. PMID- 4311236 TI - Plasma insulin: fluctuations in the "big" insulin component in man after glucose and other stimuli. AB - Plasma was filtered on G50 Sephadex, and two components of circulating insulin, "little" insulin and "big" insulin, were measured by immunoassay. The former component is indistinguishable from insulin, whereas the latter more closely resembles proinsulin and the other insulin-like substances isolated from the pancreas. In thin normal subjects, the fraction of plasma insulin that was big insulin (per cent "big"). 15-30 min after oral glucose, was less than 5%; per cent big rose 2- to 8-fold over the next hour and by 90-120 min represented 5-29% of the plasma insulin. In young thin subjects with idiopathic glucose intolerance associated with normal concentrations of plasma insulin, an identical pattern of big insulin was observed. In thin subjects in whom elevations of per cent big at 90-120 min during the standard test were only modest, starvation for 48 hr before the glucose administration resulted in a more pronounced rise in the per cent big insulin. Early after glucose administration to obese and acromegalic subjects, the per cent big was higher than in thin subjects. The magnitude of the elevation was roughly correlated with elevations in the fasting plasma insulin concentration. By 90-120 min, the per cent big in obese and acromegalic patients was the same range as in the thin subjects. Intravenously administered arginine and tolbutamide in a small number of subjects yielded a response that was similar to oral glucose; the per cent big was low early after stimulation and increased with time. In two patients with islet cell carcinomas, the per cent big was in the same range as in normal subjects. PMID- 4311237 TI - Decreased myocardial adenyl cyclase activity in hypothyroidism. AB - It has been suggested that hypothyroidism may alter the responsiveness of the heart to sympathetic stimulation. To define more precisely the interrelationship between hypothyroidism and catecholamine responsiveness we: (a) studied the effects of norepinephrine and fluoride on the activation of adenyl cyclase in the particulate fraction of heart homogenates from euthyroid and hypothyroid cats; and (b) assessed the contractile response of isolated right ventricular papillary muscles from the same cats to increasing concentrations of norepinephrine. It was found that maximal accumulation of cyclic 3',5'-adenosine monophosphate (3',5' AMP) was significantly lower at peak norepinephrine concentrations in the hypothyroid (284 +/-5 pmoles) than in the euthyroid group (326 +/-10 pmoles) (P < 0.02). However, the K(m) for norepinephrine was similar in both groups (1-2 x 10( 5) moles/liter), and there was no apparent change in the threshold concentration. Fluoride-mediated increases in Cyclic 3',5'-AMP accumulation were also significantly lower in the hypothyroid (585 +/-25 pmoles) as compared to the euthyroid group (790 +/-20 pmoles) (P < 0.02). In contrast, norepinephrine produced a similar augmentation of contractility in isolated papillary muscles from the hypothyroid and euthyroid cats. It thus appears that although the hypothyroid state is associated with a decrease in the total amount of myocardial adenyl cyclase per milligram of tissue capable of being activated by norepinephrine or fluoride, there is no change in the sensitivity of the enzyme to norepinephrine stimulation. Moreover, the finding that the inotropic response to norepinephrine is unaltered in hypothyroidism is compatible with the hypothesis that only a fraction of the total intracellular cyclic 3',5'-AMP produced by norepinephrine activation of adenyl cyclase is required to elicit the inotropic response. PMID- 4311238 TI - [House epidemic due to adenovirus]. PMID- 4311239 TI - [Experimental studies on the intralamellar use of antibiotics]. PMID- 4311240 TI - [Conservative treatment of dacryostenosis]. PMID- 4311241 TI - Studies on the carbohydrate metabolism of third-stage Haemonchus contortus larvae. PMID- 4311242 TI - Immunologic tolerance and adoptively transferred immunity in polyoma virus tumor repression. PMID- 4311243 TI - Sleep: physiologic aspects. PMID- 4311244 TI - The glioma-polyposis syndrome. PMID- 4311245 TI - Pulmonary infection due to rhinovirus type 13. PMID- 4311246 TI - Nature of renal phosphate leak. PMID- 4311247 TI - Fluoride toxicity in the chick. PMID- 4311248 TI - Genetic resistance to leukosis caused by the JM virus in the fowl. PMID- 4311249 TI - On the conformations of hallucinogenic molecules and their correlation. AB - There are only a few possible conformations of D-lysergic acid diethylamide and hallucinogenic derivatives of tryptamine and phenylethylamine. Of these possible conformations there is a high structural correlation among the probable conformations of active hallucinogenic molecules and between these conformations and the known conformations of several central nervous system transmitter molecules. PMID- 4311250 TI - A nondefective (competent) adenovirus-SV40 hybrid isolated from the AD.2-SV40 hybrid population. AB - A new nondefective hybrid virus has been plaque-isolated from the Ad.2-SV40 hybrid population. This virus replicates efficiently with one-hit kinetics in both human embryonic kidney and African green monkey kidney cells, induces an SV40 specific antigen which is detectable by immunofluorescence and complement fixation using sera from SV40 tumor-bearing hamsters, and produces SV40-specific RNA detectable by DNA-RNA hybridization. The SV40-specific antigen induced by this virus is heat-stable, sensitive to inhibitors of DNA synthesis, serologically different from SV40 T and viral antigens, and is an unrecognized SV40 antigen. PMID- 4311251 TI - Biochemical evidence for induction by polyoma virus of replication of the chromosomes of mouse kidney cells. AB - It was shown earlier that in cultures of contact-inhibited mouse kidney cells infection with polyoma virus induces replication of the chromosomal DNA. In this paper we present evidence, based on analyses of isolated chromatin, that, parallel with and as a consequence of the virus-induced synthesis of cellular DNA, the chromosomal proteins are synthesized in the proportions characteristic of normal chromosome replication. These results are compatible with the hypothesis that polyoma virus activates (or derepresses) a regulatory system of the host cell which controls initiation of chromosome replication. PMID- 4311252 TI - Gangliosides in DNA virus-transformed and spontaneously transformed tumorigenic mouse cell lines. AB - In mouse cell lines transformed by SV40 virus, a decrease was observed in the higher ganglioside homologues disialo-ceramidetetrahexoside and monosialo ceramidetetrahexoside. Such change was observed only in cells which carry the virus genome, and it correlated with increased saturation density in tissue culture and with rejection in immunologically competent syngeneic host. This indicates that the change is one of the virus-regulated functions, and it is postulated that it relates to the rejection of the virus-transformed cells. PMID- 4311253 TI - Interaction of the carbohydrate-binding protein concanavalin A with normal and transformed cells. AB - It has been shown that the carbohydrate-binding protein concanavalin A (ConA) can agglutinate leukemic cells and cells transformed by polyoma virus, simian virus 40, chemical carcinogens, and X-irradiation. This protein did not agglutinate normal cells under the same conditions. The agglutination was reversed by competition with alpha-methyl-D-glucopyranoside (alpha-MG), a carbohydrate that strongly binds to ConA, but not by the carbohydrates alpha-methyl-L fucopyranoside or N-acetylglucosamine, with no binding or weak binding to ConA. Destruction of the alpha-MG binding sites of the native protein by removal of bivalent metal ions abolished the agglutination produced by the native protein. The treatment of cells with trypsin resulted in the agglutination of normal cells by ConA and a decrease of agglutinability of transformed cells. When nonagglutinating untransformed 3T3 cells were infected with simian virus 40 and normal rat cells were infected with polyoma virus, the infected cells became agglutinable several days after virus infection. The percentage of cells agglutinated, about 50 per cent, was much higher than the percentage of cells hereditarily transformed. The results indicate that the surface membrane of transformed cells contains sites that interact with the alpha-MG binding sites of ConA, that such sites can be found on the surface membrane of normal cells after treatment with trypsin, and that the change in the surface structure from normal to transformed occurs in cells that are abortively transformed. PMID- 4311254 TI - An assessment of various methods of treatment of idiopathic orthostatic hypotension. PMID- 4311255 TI - [Anemia during pregnancy]. PMID- 4311256 TI - [Avitaminosis K in the newborn infant]. PMID- 4311257 TI - [Digestive morbidity associations of coronary disease. Pathogenesis]. PMID- 4311258 TI - [Effect of small doses of incorporated radioactive substances on processes of cholinergic transmission]. PMID- 4311259 TI - Granular cell "myoblastoma" of the breast. PMID- 4311260 TI - Carcinoma of the body of the uterus in Jamaica. PMID- 4311261 TI - The treatment of (intestinal amoebiasis) with a single dose of humatin. PMID- 4311262 TI - [Histology, histochemistry and ultrastructure of islet tumors]. PMID- 4311263 TI - [Rare tumors of the female genital tract: mullerian tumor of the uterus. Definition of the concept of mullerian tumor and its distinction from mesodermal mixed tumors]. PMID- 4311264 TI - [Fibroangioma of the small intestine. Apropos of 4 observed cases]. PMID- 4311265 TI - [Anatomo-pathological and clinical considerations on a tumor of synovial origin]. PMID- 4311266 TI - Action of polymixin and compound 48-80 on calcification in vitro. PMID- 4311267 TI - [Influence of ion factors on the pressor action of exogenous angiotensin in humans]. PMID- 4311268 TI - [The isoenzymes of lactate dehydrogenase (LDH) and of leucine aminopeptidase (LAP) in some hepatopathies of the infantile age]. PMID- 4311269 TI - [Appearance of zonality in the liver (histochemical study)]. PMID- 4311270 TI - [Involvement of the eye in hereditary metabolic diseases in children]. PMID- 4311271 TI - [Goals and results of our retinoblastoma department]. PMID- 4311272 TI - [Therapeutic possibilities of unilateral congenital cataract]. PMID- 4311273 TI - [Visually evoked EEG potential of the visual cortex in optic nerve diseases]. PMID- 4311274 TI - [Multiple abnormalities resembling Apert's syndrome]. PMID- 4311275 TI - [On the direct and indirect renal effects of angiotensin II in humans]. PMID- 4311276 TI - [Incubation of female rat and rabbit liver slices with 3H-6,7-estron sulfate]. PMID- 4311277 TI - [Cell wall of a virulent human strain of Mycobacterium tuberculosis. 1. Preparation and chemical analysis]. PMID- 4311278 TI - [Experimental study of the action of some carcinogens on the trout liver]. PMID- 4311279 TI - [Allergic reactions during bronchography with the use of sulfoiodol and barium sulfate]. PMID- 4311280 TI - [Study of the role of adenoviruses in epidemic hepatitis (Botkin's disease)]. PMID- 4311281 TI - [Serological types of strains of B. pertussis isolated in the Warsaw area and evaluation of their histamine-sensitisation potential for mice]. PMID- 4311282 TI - [Use of tissue culture for isolation of herpes simplex virus]. PMID- 4311284 TI - [Survival of poliovirus in a frozen state]. PMID- 4311283 TI - [Early changes in cells infected with adenovirus]. PMID- 4311285 TI - [Radiation therapy of soft tissue sarcomas]. PMID- 4311286 TI - [The Zollinger-Ellison syndrome in ectopic ulcerogenic pancreatic neoplasm in the liver]. PMID- 4311287 TI - [Anesthesiologic considerations on some cases of tracheal resection for neoplasms]. PMID- 4311288 TI - [Granulocytic intranuclear inclusion bodies and infection of type 3 parainfluenza myxovirus]. PMID- 4311289 TI - [Clinico-statistical observations on 62 cases of tumors of the parotid gland treated with cesium therapy]. PMID- 4311290 TI - Cyclic AMP and enzyme secretion by the isolated rabbit pancreas. PMID- 4311291 TI - [Faculty of Medicine of Paris, Chair of Electroradiology: inaugural lecture]. PMID- 4311292 TI - [Oral contraceptives and cell division]. PMID- 4311293 TI - [Disorders of heme synthesis during anemia and chronic liver diseases]. PMID- 4311294 TI - [Unusual radiologic aspect of a mediastinal hematoma]. PMID- 4311295 TI - [Treatment of tetanus with diazepam in patients over 60. Apropos of 26 cases]. PMID- 4311296 TI - [Current questions on the drug therapy of hyperthyroidism]. PMID- 4311297 TI - Schwann cell "necrosis" in unmyelinated nerve fibres of patients with polyneuropathy. PMID- 4311298 TI - Fine structure and enzyme histochemistry of developing duodenal epithelium of the chicken. PMID- 4311299 TI - [Enzyme histochemical studies of the salt gland of ducks (Anas platyrhynchus). II. Cytochemical localization of some hydrolases]. PMID- 4311300 TI - [Angiofibroma of the nose in a 14-day-old infant girl]. PMID- 4311301 TI - [Malignant tumors of the middle ear]. PMID- 4311302 TI - [On the effect of the adenylic acid system on the activity of yeast alcohol dehydrogenase]. PMID- 4311303 TI - [Electron spin resonance studies on the reaction of azide catalase with hydrogen peroxide]. PMID- 4311304 TI - Relation between chromosomal changes and succinodehydrogenase activity in the Detroit-6 (VA) cell line. PMID- 4311305 TI - [Effect of morphocycline, levomycetin and their combination on pathogenic Clostridia and experimental anaerobic (gaseous) infection]. PMID- 4311306 TI - [Stimulation of interferon formation in tissue culture by means of 8 mercaptoadenine]. PMID- 4311307 TI - [Current methods of determination of the sensitivity of bacteria to antibiotics and their significance for rational antibiotic therapy]. PMID- 4311308 TI - [Modulation of synaptic transmission in the somato-sensory system during deep sleep]. PMID- 4311309 TI - [Reproduction of the extra-adrenal effects on the CNS of ACTH using pituitary extracts]. PMID- 4311310 TI - [Karyotype studies of an ascites tumor (Yoshida hepatoma)]. PMID- 4311311 TI - Titanium in mandibular replacement. PMID- 4311312 TI - [Occurrence and distribution of cytomegalovirus infection in the area of Lyon (preliminary serologic survey using complement fixation tests)]. PMID- 4311313 TI - Comparative histochemical studies on the activity of some enzymes in chick embryo chorio-allantoic membranes infected with vaccinia smallpox viruses. PMID- 4311314 TI - [Pathogenetic considerations on idiopathic congenital nystagmus]. PMID- 4311315 TI - [Benign tumors of the tongue. Observations and considerations on the more unusual forms]. PMID- 4311316 TI - Correlates of home dream recall: reported home sleep characteristics and home dream recall. PMID- 4311317 TI - Some effects of pentobarbital and strychnine on transmission through the ventrobasal complex of the cat thalamus. PMID- 4311318 TI - Comparative effects of reserpine on the sleep cycle of man and cat. PMID- 4311319 TI - A brain perfusion technique adapted for the study of drugs which may affect the peripheral circulation through a central action. PMID- 4311320 TI - Effect of false transmitters on norepinephrine synthesis. PMID- 4311321 TI - Mechanism of vascular resistance changes produced in skin and muscle by halothane. PMID- 4311322 TI - Simultaneous assay of angiotensin I and II and determination of converting enzyme activity. PMID- 4311323 TI - Angiotensin blocking actions of guancydine. PMID- 4311324 TI - [Prevention of hemorrhage in eye surgery]. PMID- 4311325 TI - [Unusual peripheral neuropathies. Introduction. Anatomo-pathology]. PMID- 4311326 TI - [Unusual peripheral neuropathies. Introduction. Electrophysiology]. PMID- 4311327 TI - [Acute peripheral neuropathies associated with brucellosis. 2 cases]. PMID- 4311328 TI - [Peripheral neuropathy caused by hypokalemia in patients taking laxatives. 2 cases]. PMID- 4311329 TI - [Chronic peripheral neuropathy and perphyria]. PMID- 4311330 TI - [Effect of x-ray contrast substances on the dose field]. PMID- 4311331 TI - [Primary neoplasms of the trachea]. PMID- 4311332 TI - [Cervical myelopathies caused by narrowness of the spinal canal]. PMID- 4311333 TI - [Hepatitis and cytomegalovirus]. PMID- 4311334 TI - [Symptoms ascribed to enterobiosis, analyzed among children living in an institution]. PMID- 4311335 TI - [Isoniazid and carcinogenesis]. PMID- 4311336 TI - [A clinical form of angina pectoris: Prinzmetal's angor]. PMID- 4311337 TI - [Scapulo-peroneal myopathies 14 cases including 8 with facial involvement]. PMID- 4311338 TI - [Tarsal tunnel syndrome and local post-traumatic disease. 1 case]. PMID- 4311339 TI - [Comparative early and late results obtained in the reduction of auricular fibrillation by medical treatment ad electric countershock]. PMID- 4311340 TI - [The course of acute leukemia. 456 cases]. PMID- 4311341 TI - [A case of endocardial fibroelastosis with anaerobic corynebacteria in the endocavital thrombus]. PMID- 4311342 TI - [Tuberculous Nemesis]. PMID- 4311343 TI - [Mucopolysaccharides in tumors of the ovaries]. PMID- 4311344 TI - [Induction of tumors in adult rats with Rous chick sarcoma virus]. PMID- 4311345 TI - [Morphologic characteristics of spontaneous tumors and leukoses in 1st generation C47B1XCBA hybrid mice]. PMID- 4311346 TI - [Prognosis following resection of the stomach for cancer from the point of view of medical disability evaluation]. PMID- 4311347 TI - [Use of infectious and oncogenic viruses as helpers for defective Rous virus]. PMID- 4311348 TI - [The infectivity of Sendai virus ribonucleoprotein]. PMID- 4311349 TI - [The effect of DEAE-dextran on the multiplication of para-influenza viruses types 1, 2, and 3]. PMID- 4311350 TI - [Cross immunofluorescence between adenoviruses of various types]. PMID- 4311351 TI - [Obtaining hemaglutinating antgens of para-influenza viruses]. PMID- 4311352 TI - [Ultrastructure of the blood platelets in thrombasthenia]. PMID- 4311353 TI - [Thyroxine-binding capacity and iodine content of the serum during the use of iodine-containing x-ray contrast agents]. PMID- 4311354 TI - [Study on acute respiratory tract infections in children. 2. Virological and seroepidemiological study on acute respiratory tract infections in children]. PMID- 4311355 TI - [Encephalogram changes in common manifestations of herpetic primoinfection]. PMID- 4311356 TI - Sleep and instinctive behavior. PMID- 4311357 TI - Electrophysiological investigations on the pathways from cerebral cortex to the anterior lobe of cerebellum. PMID- 4311358 TI - An electrical investigation of the efferent pathways from the vestibular nuclei. PMID- 4311359 TI - Dorsal root potentials in the lumbar cord evoked from the vestibular system. PMID- 4311360 TI - Vestibular control of transmission in primary afferents to the lumbar spinal cord. PMID- 4311361 TI - Primary afferent depolarization in the lumbar cord evoked from the fastigial nucleus. PMID- 4311362 TI - [Adrenal cortex function tests using ACTH synthesized with 24 amino acids]. PMID- 4311363 TI - [Column chromatography--isolation and analysis of lipid soluble low-molecular compounds]. PMID- 4311364 TI - [Delayed reaction of Hodgkin's disease lymphocytes to phytohemagglutinin]. PMID- 4311365 TI - [Endogenous idiohypophyseal diabetes mellitus]. PMID- 4311366 TI - [Diagnosis of secondary hyperaldosteronism]. PMID- 4311367 TI - Further studies of the viruses of the chimpanzee I. Viral infection of colony maintained chimpanzees. PMID- 4311368 TI - Further studies of the viruses of the chimpanzee. II. Viral infection in recently imported chimpanzees captured in Africa. PMID- 4311369 TI - [Stereotactic interstitial brachytherapy using Ir192-"GammaMed" in infiltrating brain neoplasms]. PMID- 4311370 TI - [Electrolytes as determining factors of hemagglutination in myxovirus]. PMID- 4311371 TI - [Effect of 2,6-dichlorphenylamino-imidazoline-HCl on blood pressure and plasma renin activity in rats]. PMID- 4311372 TI - [Blood volume distribution and angiotensin determination in plasma]. PMID- 4311373 TI - [Renin, angiotensinase and converting enzyme determinations on single microdissected juxtaglomerular apparatus and parts of the nephron]. PMID- 4311374 TI - Effect of hormones on muscle action potentials, contractions and temperature in rats. PMID- 4311375 TI - [Kinins--an example of tissue hormones]. PMID- 4311376 TI - Axoplasmic transport in the crayfish nerve cord. AB - Axoplasmic proteins in the crayfish nerve cord were labeled by the incorporation of high specific activity (3)H-leucine that was injected into one of the abdominal ganglia. The labeled proteins moved caudad as a sharply defined peak at 1.1 mm/day. The level of radioactivity in the cord decreased slowly as the peak approached the tail. From the sharpness of the peak and the low decrement of label with distance it is deduced that the axoplasm is probably a gel, and some of it is not consumed as it is transported along the axon but reaches the terminal and, perhaps, the synaptic regions. PMID- 4311377 TI - RNA synthesis in cells infected with herpes simplex virus. II. Evidence that a class of viral mRNA is derived from a high molecular weight precursor synthesized in the nucleus. AB - Viral RNA extracted from the cytoplasmic polyribosomes of human epidermoid carcinoma no. 2 cells infected with herpes simplex virus (mRNA) had a sedimentation coefficient between 10S and 20S while that from nuclei of infected cells varied in size from 10S to >80S. Estimates of the maximum molecular weight of viral RNA from its sedimentation coefficients suggest that at least 10 per cent of the viral genome is transcribed as a single molecule. The ratio of RNA of different sizes found in the nuclei of cells pulse labeled for 12 minutes was approximately the same as those found in cells labeled for longer intervals implying that either some classes of viral mRNA were made as small molecules or that the large viral RNA molecules were cleaved soon after synthesis. Cytoplasmic mRNA competed to a level of at least 80 per cent in viral DNA-RNA hybridization tests with >50S RNA extracted from nuclei of infected cells. This is consistent with the hypothesis that viral mRNA is produced by cleavage of a large precursor RNA molecule. PMID- 4311378 TI - The replication of the ring-shaped DNA of polyoma virus. I. Identification of the replicative intermediate. AB - The replication of the ring-shaped polyoma DNA has been investigated. The replicative intermediate has been identified and characterized; it consists of molecules containing both circular and nicked strands, not longer than the strands of the DNA found in viral particles. The findings exclude certain proposed methods of replication of ring-shaped DNA and are compatible with Cairns' model. PMID- 4311379 TI - Stable free-radical forms of plasma proteins or simpler related structures which induce brain excitatory effects. AB - Stable free radicals have been prepared from purified plasma proteins, pituitary peptides, and simpler related structures like 5-OH tryptophan and melatonin by oxidation with the free-radical nitrosyl disulfonate in alkaline solution under controlled conditions. The presence of tyrosine or trytophan amino acid residues in the protein was found essential for free-radical formation. These red-colored, stable free radicals showed electron spin resonance spectra in aqueous solutions at room temperature and maintained this characteristic for weeks when stored at 5 degrees C. Illumination, by visible light, of the free-radical proteins and peptides separated from excess nitrosyl disulfonate by salt fractionation or chromatography enhanced the free-radical concentration in the light. The increased signal decayed in the dark. Intravenous administration of the free radical proteins or peptides into rabbits equipped with chronic cranial electrodes and sedated with a small dose of pentobarbital caused a sudden EEG arousal accompanied by behavioral changes indicative of brain excitation. Illumination of the free-radical compounds prior to administration enhanced the effects. Untreated control proteins or peptides had no effects. The observations are interpreted to suggest the involvement of free-radical structures in the transfer of energy in nervous tissue. PMID- 4311381 TI - [Method for the study of chemical structure of the bacterial cell wall. 3. Identification and determination of structural constituents of cell wall peptide glycan]. PMID- 4311380 TI - [Phospholipid splitting enzymes. 3]. PMID- 4311382 TI - [Morphologic change in the comparative pathology of child and adult]. PMID- 4311384 TI - [Formation of the general practitioner]. PMID- 4311383 TI - he effect of depot ACTH on the adrenal cortex in high and low spontaneous activity. PMID- 4311385 TI - [Anatomo-pathological study of digital hippocratism]. PMID- 4311387 TI - [sychiatric hospitalization in open wards]. PMID- 4311386 TI - [Encephalopathy and tuberculostatics]. PMID- 4311388 TI - [Significance of the viscosity of the oil preparations in lymphography]. PMID- 4311389 TI - [An electron microscopic study of foot-and-mouth disease virus]. PMID- 4311390 TI - [Biological properties of the A22 foot-and-mouth disease virus]. PMID- 4311391 TI - [Detection of avian leukosis in chick embryos by the method of Rubin]. PMID- 4311392 TI - [Isolation of foot-and-mouth disease virus from swine that is apathogenic to cattle]. PMID- 4311393 TI - [The viability of foot-and-mouth disease virus in air]. PMID- 4311394 TI - [Polychemotherapy of malignant tumors and hemoblastoses]. PMID- 4311395 TI - [Activity of aminopeptidase towards angiotensin II-amide in the serum during normal health, pregnancy, hypertension and liver disease]. PMID- 4311396 TI - [pH-dependence, inhibition and reactivation of angiotensin II and angiotensin II amide splitting enzymes in human plasma]. PMID- 4311397 TI - Comparative trial with highly purified natural ACTH, synthetic ACTH 1-24 peptide and synthetic ACTH 1-39 peptide. PMID- 4311398 TI - The effect of pyruvic acid on the growth of Bordetella pertussis. PMID- 4311399 TI - Nervous system complications in bacterial endocarditis. PMID- 4311400 TI - The effect of oral framycetin upon colon flora and upon abscess formation about colon wounds in dogs. PMID- 4311401 TI - Biochemical changes in the musculus complexus of the chick (Gallus domesticus). PMID- 4311402 TI - The lipid composition of whole plasma of Hampshire sheep, Ovis aries. PMID- 4311403 TI - Intracellular distribution of enzymes catalyzing succinate production from glucose in Rangia mantle. PMID- 4311404 TI - Some interesting skin tumours met with in the skin department General Hospital Madras between 1964 and 1968. PMID- 4311405 TI - Determination of prostaglandins by gas-liquid chromatography. PMID- 4311406 TI - Single-stage clean-up of animal tissue extracts for organochlorine residue analysis. PMID- 4311407 TI - Analytical and preparative column chromatography of neutral lipids with continuous monitoring of the eluate by a flame ionization detector. PMID- 4311408 TI - Detection of chlorpromazine and thioridazine metabolites in human erythrocytes. PMID- 4311409 TI - A simple thin-layer chromatography method for separating the ergotoxine alkaloids. PMID- 4311410 TI - The separation of neomycin sulphate, polymyxin B sulphate and zinc bacitracin. PMID- 4311411 TI - [Problems in herpes virus infections]. PMID- 4311412 TI - [Hypertension and endocrinology]. PMID- 4311413 TI - Electron microscopy of equine infectious anemia virus. AB - Equine infectious anemia (EIA) virus was observed in thin sections of infected cultured horse leukocytes by electron microscopy. The virus particles had a spherical shape and were between 80 and 120 nm in diameter. Most of them contained an electron-dense nucleoid 40 to 60 nm in diameter. They were observed to form by a process of budding from the plasma membrane and appeared to have thin surface projections. The particles described were not detected in uninfected cultured cells, and their appearance could be prevented by adding EIA immune serum to the inoculum. The implications of these findings in the classification of EIA virus are discussed. PMID- 4311414 TI - [Surgico-clinical study of 54 cases of cystadenoma phyllodes--including 2 malignant cases]. PMID- 4311415 TI - [Hypoglycemia and its countermeasures]. PMID- 4311416 TI - [Pathological biochemistry of tumor-bearing animals. 4. Application of experimental tumors for clinical study. Cholinesterase]. PMID- 4311417 TI - [Peripheral nerve biopsy]. PMID- 4311418 TI - Ultrastructure of an intermediate Sertoli-Leydig cell tumor. A histogenetic misnomer. PMID- 4311419 TI - [Neuralgic amyotrophy]. PMID- 4311420 TI - [Activity of cytochrome oxidase in the kidney of rats in the course of experimental crush syndrome]. PMID- 4311421 TI - The dependency of intrarenal distribution of single nephron filtration rates on dietary salt intake (micropuncture studies). PMID- 4311422 TI - Reactions to pathogenic viruses. PMID- 4311423 TI - The epidemiology of viruses: antigenicity and evolution. PMID- 4311424 TI - The general practitioner and the virus laboratory. PMID- 4311425 TI - [Treatment of infantile encephalopathies with spasms and hypsarrhythmia]. PMID- 4311426 TI - [Electrophoretic behavior of serum proteins and total proteinemia in children treated with high doses of ACTH. (Radial electrophoresis on cellulose acetate gel)]. PMID- 4311427 TI - [Surgical case of double tumor of the uterus and stomach]. PMID- 4311428 TI - The grading of commercially bred laboratory animals. PMID- 4311429 TI - Six years experience with herpes simplex virus in a children's home. PMID- 4311430 TI - [Clinical and biological study of a case of paraneoplastic hypercorticism in association with a malignant nesidioblastoma]. PMID- 4311431 TI - Application of test of adrenocortical sensitivity to bioassay of ACTH and to assessment of possible altered adrenocortical sensitivity. PMID- 4311432 TI - Brain monoamines and stimulation or inhibition of ACTH release. PMID- 4311433 TI - Further studies on the mechanism of the musculotropic activity of angiotensin and tyramine on the isolated guinea-pig seminal vesicle. PMID- 4311434 TI - An experimental study of current therapeutic approaches to endotoxin shock. PMID- 4311435 TI - [Effect of a trypsin and kallikrein inactivator in MHV3 induced experimental hepatitis in mice]. PMID- 4311436 TI - [Virus-induced chromosome changes in human amniotic cells in continuous line (AUP cells) chronically infected with Myxobvirus parainfluenzae 2 (Virus CA)]. PMID- 4311437 TI - Calcium ion-induced uptakes and transormations of substrates in liver mitochondria. AB - Substrate-depleted rat liver mitochondria will reaccumulate malate, succinate, oxoglutarate, beta-hydroxybutyrate and glutamate if provided with an energy source and Ca(2+) (or Ca(2+) and Mn(2+)). The energy requirement for ion uptake by fresh mitochondria causes a transient oxidation of their NADH and presumably this leads to an increased oxaloacetate concentration. A consequence is the promotion of formation of citrate, which tends to remain in the particles, provided the pH is above 7. Analyses made of systems blocked with fluorocitrate show that citrate accumulates when Ca(2+) is added with the following substrates; (a) pyruvate in the presence of ATP or malate, (b) palmitoyl-l(-)-carnitine in presence of malate and (c) oxoglutarate. Lowering the pH, even to 6.8, causes the citrate to emerge. This could be the basis of a cellular control mechanism. The generation of citrate in response to Ca(2+) can explain the stoichiometry of one proton ejected per Ca(2+) ion taken up. The new carboxyl group formed from acetyl CoA when it condenses with oxaloacetate provides an internal anionic charge and a proton to emerge when Ca(2+) enters. PMID- 4311438 TI - Investigations on metabolites of vitamin D in rat bile. Separation and partial identification of a major metabolite. AB - 1. Young rats with cannulated bile ducts were given 0.34mg. of [1alpha (3)H]cholecalciferol or 0.54mg. of [(14)C]ergocalciferol by intravenous infusion. Of the radioactivity in the dose of [1alpha-(3)H]cholecalciferol 31% was recovered in bile within 24hr. 2. The metabolites in bile were separated by gradient-elution column chromatography on silicic acid into five components, all more polar than cholecalciferol or 25-hydroxycholecalciferol. [(14)C]Ergocalciferol gave a similar pattern of metabolites in bile. 3. The three most polar metabolites were shown to be ionic. The major component has been identified as a glucuronide conjugate, which was not identical with synthetic cholecalciferyl glucuronide. PMID- 4311439 TI - Nicotinate, quinolinate and nicotinamide as precursors in the biosynthesis of nicotinamide-adenine dinucleotide in barley. AB - 1. The relative efficiencies of nicotinate, quinolinate and nicotinamide as precursors of NAD(+) were measured in the first leaf of barley seedlings. 2. In small amounts, both [(14)C]nicotinate and [(14)C]quinolinate were quickly and efficiently incorporated into NAD(+) and some evidence is presented suggesting that NAD(+) is formed from each via nicotinic acid mononucleotide and deamido NAD. 3. [(14)C]Nicotinamide served equally well as a precursor of NAD(+) and although significant amounts of [(14)C]NMN were detected, most of the [(14)C]NAD(+) was derived from nicotinate intermediates formed by deamination of [(14)C]nicotinamide. 4. Radioactive NMN was also a product of the metabolism of [(14)C]nicotinate and [(14)C]quinolinate but most probably it arose from the breakdown of [(14)C]NAD(+). 5. In barley leaves where the concentration of NAD(+) is markedly increased by infection with Erysiphe graminis, the pathways of NAD(+) biosynthesis did not appear to be altered after infection. A comparison of the rates of [(14)C]NAD(+) formation in infected and non-infected leaves indicated that the increase in NAD(+) content was not due to an increased rate of synthesis. PMID- 4311440 TI - Temperature and the regulation of enzyme activity in poikilotherms. Fructose diphosphatase from migrating salmon. AB - 1. The calculated energy charge of the liver cell from migrating salmon is very low (0.464), in keeping with the extended starvation and high rates of muscular and biosynthetic activity of these organisms. 2. Affinity of fructose 1,6 diphosphatase for substrate increases with a decrease in temperature. 3. Arrhenius plots of the saturation kinetics are complex and suggest an interconversion of one or more forms of the enzyme; this interconversion is dependent on the identity of the cofactor. 4. Affinity of salmon fructose 1,6 diphosphatase for its allosteric inhibitor (AMP) is lower than in other fructose 1,6-diphosphatases and this enzyme-AMP interaction is largely insensitive to temperature. The functional significance of diminished AMP-sensitivity is that it allows normal or high fructose 1,6-diphosphatase activity during a low energy charge. 5. These findings suggest mechanisms for the maintenance of high rates of gluconeogenesis in salmon during spawning migration. PMID- 4311441 TI - The configuration of 2,6-diamino-3-hydroxypimelic acid in microbial cell walls. AB - beta-Hydroxydiaminopimelic acid, together with some diaminopimelic acid, occurs in the cell-wall mucopeptide of certain Actinomycetales. These components were converted into their di-DNP derivatives and separated by chromatography. Hence the relative proportions present in the cell walls of a number of species were measured. The problem of acid-induced inversion of configuration was studied. Of the diaminohydroxypimelic acids isomer B (see Scheme 2; amino groups meso, hydroxy group threo to its neighbouring amino group) always predominated but a small proportion of isomer D (amino groups l, hydroxy group erythro) also occurred. The configuration of the diaminohydroxypimelic acids was determined by periodate oxidation to glutamic gamma-semialdehyde, which underwent spontaneous ring-closure. Reduction with sodium borohydride produced optically active proline, the configuration of which was determined by direct measurement of the optical rotation of DNP-proline. Un-cross-linked diaminohydroxypimelic acid in the cell wall was oxidized with periodate in the presence of ammonia. Since the remaining amino group was bound in peptide linkage, ring-closure was prevented and borohydride reduction of the aldehyde-ammonia presumed to be present resulted in the formation of ornithine. The quantity of ornithine was used as a measure of the degree of cross-linking. PMID- 4311442 TI - Separation of the bovine colostrum M-1 glycoprotein into two components. AB - 1. Two glycoproteins were isolated from the M-1 acid glycoprotein fraction of bovine colostrum. 2. The lighter glycoprotein had a molecular weight of 7200, contained about 28.4% of carbohydrate, and had an absorption maximum at 275nm. The heavier glycoprotein had a molecular weight of 12000, contained 39.0% of carbohydrate, and had no absorption maxima in the 240-300nm. range of the spectrum. 3. The carbohydrate moiety of both glycoproteins was removable from the polypeptide moiety under the conditions of the beta-elimination reaction. 4. Periodate oxidation experiments showed that sialic acid was linked to galactose in both proteins. PMID- 4311443 TI - Ribosome formation in rat liver: evidence for post-transcriptional control. PMID- 4311444 TI - [Stepwise synthesis of oligonucleotides. V. The enzymatic synthesis of diribonucleoside monophosphates of unspecified base sequences]. PMID- 4311445 TI - Reversal of N-methylisatin-beta-4',4'-dibutylthiosemicarbazone inhibition of poliovirus RNA synthesis by a photoproduct of actinomycin D. PMID- 4311446 TI - Inhibitor-contaminated NADH: its influence on dehydrogenases and dehydrogenase coupled reactions. PMID- 4311447 TI - [Aging and the adrenal cortex]. PMID- 4311448 TI - [The effect of protein synthesis inhibitors on hemagglutinin formation and on cell destruction after infection with encephalomyocarditis virus]. PMID- 4311449 TI - [Enzymatic hydrolysis of pyrophosphate bonds in serylpyrophosphates]. PMID- 4311450 TI - [Some new data on the biological effects of microwaves]. PMID- 4311451 TI - [Activation of Rous virus in "virusless" tumors of golden hamsters by artificial heterokaryons]. PMID- 4311452 TI - Hyperlactacidemia as a factor of thrombocyte adhesiveness. PMID- 4311453 TI - Influence of adrenal cortex on thyrocalcitonin content of the rat thyroid. PMID- 4311454 TI - The cytochemistry of some enzyme activities in Stellaria media embryos. PMID- 4311455 TI - [Therapeutic possibilities in tracheal tumors]. PMID- 4311456 TI - [2 cases of glomic tumors of the middle ear confined to the promontory]. PMID- 4311457 TI - The effects of protein synthesis inhibitors on angiotensin stimulated colonic fluid transfer. PMID- 4311458 TI - The effects of hypercarbia on synaptic transmission in the cuneate nucleus. PMID- 4311460 TI - [Physiopathology of renal hypertension]. PMID- 4311459 TI - The preferential release of newly synthesized transmitter by a sympathetic ganglion. AB - 1. The acetylcholine (ACh) store of cat's superior cervical ganglia was replaced with radioactive ACh by perfusion, during stimulation, with [(3)H]choline-Locke solution. Perfusion was continued with Locke containing unlabelled choline (Ch) (in physiological concentration) and the release of labelled and unlabelled ACh was measured.2. Electrical stimulation of the preganglionic sympathetic nerve (20/sec or 5/sec), or stimulation by perfusing with raised K, released ACh that had a lower specific radioactivity than ganglionic ACh. The proportion of released ACh that was labelled was slightly higher when stimulation was at lower frequency or by K.3. Preganglionic nerve stimulation released, in the first few minutes, ACh that had a specific activity 70-80% of ganglionic ACh, but after 5 min the proportion of label in the released ACh fell to 35-45% of that in the ganglion.4. It is concluded that newly synthesized ACh is released before equilibration with preformed stores, and the significance of this to the mechanism of transmitter release is discussed. PMID- 4311462 TI - [Dermatomyositis associated with development of bronchial epithelioma]. PMID- 4311461 TI - Studies of diarrhoeal diseases in Iran. I. Occurrence of bacterial infection in pre-school children on the central plateau of Iran. PMID- 4311463 TI - [A case of pituitary adenoma associated with a right parietal cystic glioma]. PMID- 4311464 TI - [Pancreatic tumor with endocrinic function]. PMID- 4311465 TI - Corticotrophin release induced by injection of formalin in rats with hemisection of the spinal cord. PMID- 4311466 TI - Pituitary-thyroid function of the rat after suppression of ACTH release by dexamethasone implants in the median eminence. PMID- 4311467 TI - Converting enzyme activity in experimental cirrhosis of the rat. PMID- 4311468 TI - [Effect of 2 anabolic steroids on "essential" delayed growth]. PMID- 4311470 TI - [Acute urinary retention in herpes zoster]. PMID- 4311469 TI - [Treatment of pituitary dwarfism with synthetic anabolic drugs]. PMID- 4311471 TI - [Appearance of infectious ribonucleic acid during a one-step growth cycle of foot and-mouth disease virus in pig kidney cells]. PMID- 4311472 TI - [Krukenberg's syndrome]. PMID- 4311473 TI - [Bronchopulmonary malignant neoplasms in females]. PMID- 4311474 TI - [Difficulties in the anatomo-clinical diagnosis of malignant tumors of the trachea]. PMID- 4311475 TI - [Tumor in the first year of life, especially on 62 nephroblastomas of newborn infants]. PMID- 4311476 TI - [The modelling of a neuron from the point of view of N.E. Vvedenskii's theory]. PMID- 4311477 TI - [New data on the mechanism of the overall effect of local anesthetics]. PMID- 4311478 TI - [Effect of antibiotics on the adhesive properties of thrombocytes]. PMID- 4311479 TI - [Effect of ACTH and corticosteroids on the fibrin stabilizing factor]. PMID- 4311480 TI - [Toxicology of ammonium perchlorate during repeated action on the organism]. PMID- 4311481 TI - [Effect of ACTH injections on the impulse activity of mesencephalic neurons]. PMID- 4311482 TI - [Effect of autonomic ganglia isolation on changes in certain physiological indices in muscle caused by ACTH administration]. PMID- 4311483 TI - [Angiographic and tomographic examination of localized glomus tumors in the aural region]. PMID- 4311484 TI - [Angiographic findings in hypophyseal adenoma]. PMID- 4311485 TI - [The postnatal development of the rat harderian gland. II. Enzyme-histochemical studies]. PMID- 4311486 TI - [Participation of the ventral posterior-lateral nucleus of the cat's thalamus in the transmission of afferent visceral signals]. PMID- 4311487 TI - [Morphologic aspects of experimental bronchial silicosis induced in rats by crystobalite and tridimite]. PMID- 4311488 TI - [Clinical use of a new synthetic ACTH]. PMID- 4311490 TI - [Tympano-jugular paragangliomas. (Considerations on 5 cases)]. PMID- 4311489 TI - [Motives and reasons which justify the use of ACTH in the therapy of epilepsy]. PMID- 4311492 TI - [Central and peripheral neuropathy associated with hyperthyroidism in a male patient]. PMID- 4311491 TI - [The association of hyperthyroidism and gynecomastia. Endocrinologic exploration of a case]. PMID- 4311493 TI - [Misleading manifestations of intestinal malabsorption]. PMID- 4311494 TI - [Intestinal enzymes of fat digestion]. PMID- 4311495 TI - [Auricular barotrauma]. PMID- 4311496 TI - [Aftereffects of single adrenal cortex stimulation on the course of urinary aldosterone excretion]. PMID- 4311497 TI - [An apparatus for the production and photodocumentation of agar gel enzyme electrophoretograms]. PMID- 4311498 TI - [Hepatitis in monkeys after inoculation with adenoviruses from patients with viral hepatitis. I. Determination of enzymatic activity during the course of the disease]. PMID- 4311500 TI - [Adaptive changes in the activity of certain blood enzymes in healthy infants]. PMID- 4311499 TI - [Epidemiology of pseudomonas infections]. PMID- 4311501 TI - [Dynamics of toxin formation in Cl. perfringens types D and E]. PMID- 4311502 TI - [Species differences in fractions of soluble antigens of parapertussis and pertussis microbes]. PMID- 4311503 TI - [Immunogenic and antigenic properties of soluble pertussis antigens]. PMID- 4311504 TI - [On the possibility of using diethylpyrocarbonate (Piref) for inactivation of pathogenic microbes]. PMID- 4311505 TI - [Cylindroma of the nasal cavity originating from the left nasal concha]. PMID- 4311506 TI - Studies on the intestinal absorption of labelled fat-soluble vitamins (A, D, E, and K) via the thoracic-duct lymph in the absence of bile in man. PMID- 4311507 TI - [Necrotizing encephalitis with cerebral cytomegalic inclusion disease in an adult -possible double viral infection in the brain]. PMID- 4311508 TI - [Histopathological study of protracted Japanese encephalitis--report of a case with 151-day duration]. PMID- 4311509 TI - The pterygopalatine fossa and canal. PMID- 4311510 TI - The disappearance of a large intracranial deposit of pantopaque twenty years after myelography. PMID- 4311511 TI - Clinical experience with a new type of contrast medium in carotid arteriography. PMID- 4311512 TI - Defective DNA animal viruses. PMID- 4311513 TI - Tumors arising from pericytes. Ultrastructure and organ culture of a case. PMID- 4311514 TI - Delayed hypersensitivity in mature pulmonary pertussis. PMID- 4311515 TI - Biosynthesis of glycosaminoglycans (mucopolysaccharides) in leukemic myeloid cells. PMID- 4311517 TI - Fish liver tryptophan pyrrolase: the apparent absence of both hormonal regulation and substrate induction. PMID- 4311516 TI - Nature of the increase in liver microsomal glucose-6-phosphatase activity during the early stages of alloxan-induced diabetes. PMID- 4311518 TI - Induction of glutamine synthetase by cortisol. PMID- 4311519 TI - Isochorismic acid: a new intermediate in the biosynthesis of 2,3-dihydroxybenzoic acid. PMID- 4311520 TI - The enhancement of phosphoryl transfer by adenosine 3',5'-monophosphate in the presence of a membranous fraction from canine kidney. PMID- 4311521 TI - UDP-glucose:glycogen alpha-4-glucosyltransferase I kinase activity of purified muscle protein kinase. Cyclic nucleotide specificity. PMID- 4311522 TI - The lipid composition of mitochondrial and microsomal fractions of human myocardial homogenates. PMID- 4311523 TI - Electrical transmission between the cells of vertebrate cardiac muscle. PMID- 4311524 TI - Neuromusclar transmission in the heart of the lobster Homarus americanus. PMID- 4311525 TI - Localization and mode of action of cardioexcitatory agents in molluscan hearts. PMID- 4311526 TI - Excitation and transmission in cardiac tissues. PMID- 4311527 TI - Association of viral ribonucleoprotein with polysomes. PMID- 4311528 TI - Administration by nasal spray of an 18 amino acid synthetic polypeptide with corticotropic action. PMID- 4311529 TI - [Electron microscopic observations of microstructure and phosphatase active portions of the human amniotic epithelium]. PMID- 4311530 TI - [Adreno-cortical steroid therapy and ACTH therapy]. PMID- 4311531 TI - Integrative activity in the nervous system: closed circuits and interneurons. PMID- 4311532 TI - Binding of spermatozoa with surface active spin labels. PMID- 4311533 TI - [Sporulation and heat-resistance of food-poisoning strains of Cl. perfringens]. PMID- 4311534 TI - [Histochemical study of the skeletal muscle--histochemical findings of the normal and hypofunctional muscles]. PMID- 4311535 TI - [Case of tarsal tunnel syndrome caused by neurilemmoma]. PMID- 4311537 TI - [Generalized thorotrastosis after ascending pyelography]. PMID- 4311536 TI - [Hashimoto's disease. Anatomical and clinical study]. PMID- 4311538 TI - The pharmacology of spinal postsynaptic inhibition. PMID- 4311539 TI - [Alveolar carcinoma]. PMID- 4311540 TI - [Analysis of bloodsucking population of Culex tritaeniorhynchus, a vector of Japanese encephalitis]. PMID- 4311541 TI - [Benign tumors of the breast]. PMID- 4311542 TI - [Physical diagnosis of breast cancer--radiological diagnosis]. PMID- 4311543 TI - Recent studies on the mode of action of scorpion neurotoxins. A review. PMID- 4311544 TI - The proteins of the parainfluenza virus SV5. 1. Separation of virion polypeptides by polyacrylamide gel electrophoresis. PMID- 4311545 TI - Induction of transplantation resistance to Rous sarcoma isograft by avian leukosis virus. PMID- 4311546 TI - Cell interaction with a synthetic polynucleotide and interferon production in vitro. PMID- 4311547 TI - [Adrenal cortex hyperfunction in a bronchial carcinoma patient with a high ACTH level. Regression following antimitotic combination therapy]. PMID- 4311548 TI - [Primary muscular tumors of the lung]. PMID- 4311549 TI - Familial hyperlipoproteinemia type 3. PMID- 4311550 TI - Focal epithelial hyperplasia in a Mexican Indian. PMID- 4311551 TI - Multiple glomus tumors with a family history. PMID- 4311552 TI - Acquired hemangiomata. PMID- 4311553 TI - Solid hidradenoma. PMID- 4311554 TI - Dream time (REM) and psychotherapy. Correlates of REM time with a patients behavior in psychotherapy. PMID- 4311555 TI - [Glomus jugulare tumor with special reference to the radiogram of the jugular foramen]. PMID- 4311556 TI - [Inappropriate secretion of antidiuretic syndrome with positive ADH bioassay]. PMID- 4311558 TI - Plaque assay of poliovirus in plastic chambers. PMID- 4311557 TI - The pathology and treatment of haematoma of the nasal septum. PMID- 4311559 TI - Soluble reduced nicotinamide adenine dinucleotide oxidase from Bacillus cereus T spores and vegetative cells. I. Purification. PMID- 4311560 TI - Soluble reduced nicotinamide adenine dinucleotide oxidase from Bacillus cereus T spores and vegetative cells. II. Properties. PMID- 4311561 TI - The importance of implantation site in cerebral carcinogenesis in rats. PMID- 4311562 TI - Isolation and chemical characterization of a cell-surface sialoglycopeptide fraction from novikoff ascites cells. PMID- 4311563 TI - Effect of hepatocarcinogens on hepatocyte DNA synthesis and cortisone induction of tryptophan oxygenase. PMID- 4311565 TI - The ultrastructure of canine cutaneous papilloma. PMID- 4311564 TI - Response of bone marrow to MC29 avian leukosis virus in vitro. PMID- 4311566 TI - Amino acid transport in rat liver and Morris hepatomas: effect of protein diet and hormones on the uptake of alpha-aminoisobutyric acid-14C. PMID- 4311567 TI - Mechanism of the reduced production of aldosterone in response to loading with physiological saline solution in the rat. PMID- 4311568 TI - Ruby laser damage and pigmentation of the iris. PMID- 4311569 TI - [Angiographic demonstration of an insuloma and an accessory spleen]. PMID- 4311571 TI - Phenotypically variant adrenal tumor cell cultures with biochemical lesions in the ACTH-stimulated steroidogenic pathway. PMID- 4311570 TI - [The periodic acid-Schiff reaction of chitin]. PMID- 4311572 TI - Density dependent inhibition of cell growth in cultures of primary and established lines of cells. PMID- 4311573 TI - Haemorrhagic smallpox. PMID- 4311574 TI - Conjunctivitis and subclinical infection in smallpox. PMID- 4311575 TI - Variability in the characteristics of pocks produced on the chick chorioallantois by white pock mutants of cowpox and other poxviruses. PMID- 4311576 TI - A comparative study of methods for the diagnosis of respiratory virus infections in childhood. PMID- 4311578 TI - Tumours of connective tissues in cattle, sheep and pigs. PMID- 4311577 TI - Airborne excretion of foot-and-mouth disease virus. PMID- 4311579 TI - Aortic body tumours in a boxer dog with a review of the literature. PMID- 4311580 TI - Studies upon the mechanism of reserpine-induced arrest of egg transport in the mouse oviduct. I. The effect of hormone replacement. PMID- 4311581 TI - [Allergy of enteroflora--cross-reactivities between Clostridium perfringens and the organs]. PMID- 4311582 TI - Serodifferentiation of poliovirus strains. II. Modified Wecker test on type 3 poliovirus strains. PMID- 4311583 TI - Antigenic characterization of poliovirus strains by neutralization kinetic studies and the modified Wecker technique. PMID- 4311584 TI - Variants of Japanese encephalitis virus cytopathic for L mouse fibroblasts and lass human epithelial cells. PMID- 4311585 TI - Selective determination of hemolytic activity of alpha or theta toxin of Clostridium perfringens. PMID- 4311586 TI - Heat-labile toxin of Bordetella pertussis purified by preparative acrylamide gel electrophoresis. PMID- 4311587 TI - [Cancer in childhood]. PMID- 4311588 TI - Synthesis of cyclic AMP in Dictyostelium discoideum and Polysphondylium pallidum. PMID- 4311589 TI - Phosphatase release of inorganic phosphorus in Lake Kinneret. PMID- 4311590 TI - [The importance of lymphography for the diagnosis of regional lymph node metastases in kidney and urinary bladder tumors]. PMID- 4311591 TI - [X-ray diagnosis of juvenile angiofibromas of the epipharynx]. PMID- 4311592 TI - [Demonstration of intradural cranial nerve sections in the pneumoencephalogram]. PMID- 4311593 TI - The development of a vaccine for bovine herpes mammillitis. PMID- 4311594 TI - [Radiologic study of the liver with thorotrast deposit--cases of thorotrast liver cancer]. PMID- 4311595 TI - Pathogenesis of hypertension in rabbits with coarctation of the abdominal aorta. PMID- 4311596 TI - [Some indices of nicotinic acid metabolism and the possibility of its use in the combined treatment of laryngeal cancer]. PMID- 4311597 TI - [Etiology of acute inflammatory diseases of upper respiratory tract and lymphadenoid pharyngeal ring (of N.I. Pirogov)]. PMID- 4311599 TI - [In vitro action of lysine-vasopressin on the concentration of ribo- and deoxyribonucleic acids in malignant cerebral tumors. New perspectives on the host tumor relationship in cancerology]. PMID- 4311598 TI - Studies on the pathogenesis and mechanism of hematologic diversification by re isolation of the myeloid leukemia virus (Graffi). PMID- 4311600 TI - [The use of delayed-action beta 1-24-corticotropin in the functional exploration of the adrenal cortex]. PMID- 4311601 TI - [Hypothalamo-hypophyso-adrenal activity under corticotherapy. Comparative study of ACTH, Synacthene, metopirone, lysine-vasopressin and pyrogen tests]. PMID- 4311602 TI - [Tropho-mesoblastoma of the ovary. Hormonal determination]. PMID- 4311603 TI - [Dysplastic replicas of endocrine tumors of the ovary]. PMID- 4311604 TI - [Vulvar hidradenoma]. PMID- 4311605 TI - [Tumor lipids. Phospholipid composition of nuclei from rat liver, ascites hepatoma and Jensen sarcoma]. PMID- 4311606 TI - [Protective effect of respiratory chain substrates on inactivation of mitochondrial electron transfer particles by proteolytic enzymes and cobra venom]. PMID- 4311607 TI - Overdose of tricyclic anti-depressants and deductions concerning their cerebral action. PMID- 4311608 TI - [Clinical features and treatment of carpal tunnel syndrome]. PMID- 4311609 TI - [Contrast media storage in the liver following foot lymphography (hepatography)]. PMID- 4311610 TI - On the mechanism of sensitivity to leucine in the case of "leucine sensitive hypoglycemia". (I). PMID- 4311611 TI - [Demonstration of FSH in swine by different immunologic methods]. PMID- 4311612 TI - The role of cyclic adenosine-3',5'-monophosphate (AMP) in gastrointestinal secretion. PMID- 4311613 TI - Effect of intravenous glucagon on circulating levels of growth hormone and 17 hydroxycorticosteroids. PMID- 4311614 TI - Anomalous response to metyrapone in Cushing's syndrome due to adrenocortical adenoma. PMID- 4311616 TI - Anabolic and androgenic affect of testosterone in sexually immature boys and its dependency on growth hormone. PMID- 4311615 TI - Effectiveness of long-term human growth hormone therapy for short stature in children with growth hormone deficiency. PMID- 4311618 TI - [Studies on adreno-cortical function of patients with tonsillar disease]. PMID- 4311617 TI - C-21 steroid metabolism and conjugation in the human premature neonate. I. Urinary excretion and the response to ACTH. PMID- 4311619 TI - Polydeoxyribouridylic acid and its complexes with polyribo- and deoxyriboadenylic acids. PMID- 4311620 TI - DNA of herpes simplex virus is not a substrate for methylation in vivo. PMID- 4311621 TI - Crystalline ternary complexes of lactate dehydrogenase. PMID- 4311622 TI - [Renin-angiotensin system. II. Renal angiotensinase activity]. PMID- 4311623 TI - Interaction of cassaine (an alkaloid showing digitalis-like actions) with drugs stimulating lipolysis in vitro. PMID- 4311624 TI - Comparative synthesis of herpes simplex virus by neonatal and mature human fibroblasts. PMID- 4311626 TI - [Significance of determination of renin-angiotensin system in hypertension]. PMID- 4311625 TI - Tricarboxylic acids cycle dehydrogenases and lactate-dehydrogenase interaction in the amphibian embryos mitochondria. PMID- 4311627 TI - [Renovascular hypertension in pregnancy]. PMID- 4311628 TI - Developmental abnormalities in the rat induced by the amino acid leucine. PMID- 4311629 TI - [Adaptation of a rat tumor to Syrian golden hamsters during 150 passages]. PMID- 4311630 TI - [Metabolism of the digitalis sugar digitoxose in the rat]. PMID- 4311631 TI - [Effect of angiotensin on the function of isolated rabbit hearts and noradrenaline release at rest and during sympathetic nerve stimulation]. PMID- 4311633 TI - [Colominic acid]. PMID- 4311632 TI - [Serum level of seromucoid-alpha-1 in patients with various neurological syndromes]. PMID- 4311634 TI - [Induction of phosphomonoesterases in microorganisms. I. Enzymatic induction depending on the condition of the culture]. PMID- 4311635 TI - [Gardner's syndrome]. PMID- 4311636 TI - Analysis of SV40-induced transformation of hamster kidney tissue in vitro. VI. Characteristics of mitomycin C induction. PMID- 4311637 TI - The participation of sendai virus ribonucleoprotein in virus-specific polysome formation. PMID- 4311638 TI - Transformation of mouse 3T3 cells by T antigen-forming defective SV40 virions (T particles). PMID- 4311639 TI - Polypeptide components of virions, top component and cores of reovirus type 3. PMID- 4311640 TI - In vitro assembly of polioviruses. I. Kinetics of the assembly of empty capsids and the role of extracts from infected cells. PMID- 4311641 TI - Temperature sensitive mutants of an avian sarcoma virus. PMID- 4311643 TI - [Identification of enterovirus by means of fluorescent antibodies]. PMID- 4311642 TI - [Growth of herpes viruses in human leucozyte cultures]. PMID- 4311644 TI - [Adenovirus 6 as the cause of epidemics]. PMID- 4311645 TI - [Intestinal invagination in monkeys of the species Saguinus (Oedipomidas) oedipus as a possible consequence of adenovirus infection]. PMID- 4311646 TI - Descending monosynaptic and reflex control of gamma-motoneurones. PMID- 4311647 TI - Bloody ascites: diagnostic implications. PMID- 4311648 TI - Cervical chemodectomas. Clinical consideration in sixteen cases. PMID- 4311649 TI - The response of reduced pyridine nucleotide to calcium-induced alkalinity. PMID- 4311650 TI - Genital infection with type 2 Herpes virus hominis. A commonly occurring venereal disease. PMID- 4311651 TI - The origin of inorganic pyrophosphate in urine. PMID- 4311652 TI - Isolated gastric parietal cells: oxygen consumption, electrolyte content and intracellular pH. PMID- 4311653 TI - [The syphilis of Ulrich von Hutten. Sensational studies of a group of experts of the medical school of the University of Zurich]. PMID- 4311654 TI - Nickel toxicity in young growing mice. PMID- 4311655 TI - Intranasal removal of a tumor from the dorsum of the nose. A case report. PMID- 4311656 TI - Carcinoma of the breast--a clinical study. PMID- 4311657 TI - Current trends in the chemotherapy of brain tumors with special reference to glioblastomas. PMID- 4311658 TI - Surgical treatment of unilateral optic nerve gliomas. PMID- 4311659 TI - Experimental intervertebral discolysis with collagenase. PMID- 4311660 TI - Herpesviruses and cancer. PMID- 4311661 TI - Rifampicin inhibits focus formation in chick fibroblasts infected with Rous sarcoma virus. PMID- 4311662 TI - Experimental infection of gibbons with rhinovirus. PMID- 4311663 TI - Antigenic variation among strains of rhinovirus type 51. PMID- 4311664 TI - Evolution of the autonomic innervation of visceral and cardiovascular systems in vertebrates. PMID- 4311666 TI - Two cases of pox in recently imported peregrine falcons (Falco peregrinus). PMID- 4311665 TI - [Renin-angiotensin research]. PMID- 4311667 TI - [Cerebral glioblastoma with cerebellar metastasis (Case report)]. PMID- 4311668 TI - Nerve impulses and trophic effect. Absence of fibrillation after prolonged and reversible conduction block. PMID- 4311669 TI - Neuropathological correlates of low-voltage EEG foci. PMID- 4311670 TI - Peripheral nerve involvement in Fabry's disease. PMID- 4311672 TI - Oral manifestations of primary hypophosphatasia. A case report. PMID- 4311671 TI - [Nosology of muscular rheumatism]. PMID- 4311673 TI - Apocrine cystadenoma. A report of two cases occurring on the prepuce. PMID- 4311674 TI - Carcinoma of the kidney. PMID- 4311675 TI - Treatment of Wilms' tumour: a review of 25 cases seen at the Sheffield Centre for Radiotherapy from 1950 to 1966 inclusive. PMID- 4311676 TI - [Differential diagnosis of papilledema (results of fluorescence retinography)]. PMID- 4311677 TI - [The differential diagnosis of binasal visual field defects]. PMID- 4311679 TI - Electron microscopy of effect of polymyxin on Escherichia coli lipopolysaccharide. AB - Polymxyin treatment of isolated lipopolysaccharide from Escherichia coli resulted in the breakdown of its structure. PMID- 4311680 TI - The effects of cyanide on oxygen consumption in bovine dental pulp. PMID- 4311681 TI - Carcinoma-in-situ of the breast. PMID- 4311683 TI - Paraganglioma. PMID- 4311682 TI - Lactic dehydrogenases of strains of the genus Leuconostoc. PMID- 4311684 TI - Carcinoma of the colon in childhood. PMID- 4311685 TI - [Effect of environmental factor and physical factor on pulmonary fibrosis]. PMID- 4311687 TI - [Pathological biochemistry of tumor-bearing animals. 3. Application of experimental tumors to clinical study. Transaminases]. PMID- 4311686 TI - [Syndrome of congenital adrenocortical unresponsiveness to ACTH]. PMID- 4311688 TI - The avian leukosis complex. PMID- 4311689 TI - Nursing after-care in psychiatry. PMID- 4311690 TI - Competitive inhibition of uridine incorporation by 6-azauridine in uninfected and mengovirus-infected Novikoff hepatoma cells. PMID- 4311691 TI - Androgen responses to stress. I. Psychoendocrine relationships and assessment of androgen activity. PMID- 4311692 TI - Contributions to the study of myocardial involvement during viral pneumopathies of sucklings. PMID- 4311693 TI - [Possible synergism of radiation and virus in leukemogenesis]. PMID- 4311694 TI - Peroxidase-mediated virucidal systems. AB - Peroxidase (myeloperoxidase or lactoperoxidase), hydrogen peroxide, and a halide such as iodide, bromide, or chloride form a potent virucidal system that is effective against polio and vaccinia viruis, particularly at a low pH. The peroxidase-halide-hydrogen peroxide system may contribute to the host defense against certain viral infections. PMID- 4311696 TI - The growth patterns of spontaneous mouse tumors. PMID- 4311695 TI - [Surgical stress and the function of the adrenal cortex--acute adrenal insufficiency in surgery]. PMID- 4311698 TI - Seal pox. Case history. PMID- 4311697 TI - [Adrenoreceptors and structure of their active centers]. PMID- 4311699 TI - Enzymes in periodontal disease. PMID- 4311701 TI - Action-oriented group therapy as a training method for psychiatric student nurses. PMID- 4311702 TI - Meeting the needs of parents with a mentally retarded child. PMID- 4311700 TI - [Histochemical studies on adenoid cystic carcinoma]. PMID- 4311703 TI - The new look. PMID- 4311704 TI - Family crisis intervention. PMID- 4311705 TI - A group therapy experience with regressed patients. PMID- 4311706 TI - Actual problems of significance, spreading, treatment and control. PMID- 4311707 TI - Politics and public care agencies. PMID- 4311709 TI - Geriatrics. PMID- 4311708 TI - Look-alike and sound-alike drugs. PMID- 4311710 TI - Education as preparation for change. PMID- 4311711 TI - [Mixed tumors of parotid gland]. PMID- 4311712 TI - [Electroencephalographic studies on the influence of radiotherapy of cerebral tumors on the effect of thiopental in humans]. PMID- 4311713 TI - [Clinical and anatomopathological data on the problem of carcinoma ex ulcera of the stomach]. PMID- 4311714 TI - Determination of quartz. Evaluation of the differential thermal analysis method. PMID- 4311715 TI - [The so-called pilar tumor of the scalp]. PMID- 4311716 TI - Evaluation of the effectiveness of temazepam on the insomnia of patients with neurosis and endogenous depression. PMID- 4311717 TI - [Electrophysiological contribution on the effect of 7-chloro-1,3-dihydro-3 hydroxy-5-phenyl-2H-1,4-benzodiazepine-2-one on day time sleep after night shift. Preliminary report]. PMID- 4311718 TI - [Effect of hormones on physical and chemical properties of connective and supporting tissue. 2]. PMID- 4311719 TI - Effects of spino-bulbo-spinal reflex volleys on flexor motoneurons of hindlimb in the cat. PMID- 4311721 TI - The role of the interstimulus interval in heterosynaptic facilitation in Aplysia californica. PMID- 4311720 TI - Spontaneous and reflex discharge of a sympathetic nerve during "para-sleep" in decerebrate cat. PMID- 4311722 TI - Pituitary-adrenal response to stress in rats with hypothalamic islands. PMID- 4311723 TI - Relation between hypothalamic heat production and intra- and extracranial circulatory factors. PMID- 4311724 TI - A comparative study of the role of the cerebral arterial blood in the regulation of brain temperature in five mammals. PMID- 4311725 TI - The time course of facilitation and inhibition in the olfactory bulb, investigated with double pulse stimulation of the lateral olfactory tract. PMID- 4311726 TI - A histochemical study of experimentally induced malignant skin tumours. PMID- 4311728 TI - Exacerbations in chronic bronchitis. PMID- 4311727 TI - Latent cytomegalovirus infection in blood donors. AB - Twenty-one out of 32 apparently healthy blood donors aged 21 to 65 years yielded positive complement fixation tests with a cytomegalovirus antigen, at titres ranging from 1:8 to 1:64. Virus was present in leucocyte cultures of fresh peripheral blood of two seropositive subjects from a total of 35 donors examined. Plasma and 48-hour stored blood specimens failed to disclose virus in culture. Viruria could not be demonstrated, and there was no evidence of recent illness in the study group. These findings suggest that subclinical viraemia is not uncommon in blood donors. PMID- 4311729 TI - [Reserved pool of the adrenal cortex in infants]. PMID- 4311730 TI - Studies on experimental autoimmune thymitis in guinea-pigs. PMID- 4311731 TI - [Comparative studies of the etiology of herpetic and aphthous stomatitis and recurrent aphthae]. PMID- 4311732 TI - Effect of triamcinolone on various calcifying connective-tissue reactions. PMID- 4311733 TI - [Hormone-induced phosphaturia: the effect of parathormone in comparison with other hormones]. PMID- 4311734 TI - [Relations between the juxtaglomerular apparatus and zona glomerulosa during NaCl loading, -deficiency and thirst]. PMID- 4311735 TI - [Effect of a single dose of ACTH. Animal experiments and clinical findings]. PMID- 4311736 TI - [Analytical studies of steroid hormones in hyperemesis gravidarum]. PMID- 4311737 TI - [Angiochemical receptors and other new intrapulmonary argentiffin structures related to the regulation of the lesser circulation]. PMID- 4311738 TI - [Nature of the synaptic receptors]. PMID- 4311740 TI - [A case of hepatoma in the scrotum]. PMID- 4311739 TI - A comparative study of different culture techniques and therapeutic efficacy of newer antibiotics in pertussis. PMID- 4311741 TI - Otosclerosis and osteogenesis and imperfecta. PMID- 4311742 TI - Poliovirus replicative intermediate: structural basis of infectivity. PMID- 4311743 TI - Endocrine function in multiple sclerosis. PMID- 4311744 TI - Response to long-term administration of human growth hormone in Turner's syndrome. PMID- 4311745 TI - Effects of slow wave sleep deprivation on human growth hormone release in sleep: preliminary study. PMID- 4311746 TI - [2 cases of idiopathic thrombopenic purpura treated effectively with imuran and glucocorticoids]. PMID- 4311747 TI - [Differential diagnosis and combined treatment of parotid gland tumors]. PMID- 4311748 TI - Effects of gamma radiation on the chemical and physical properties of lactate dehydrogenase. PMID- 4311749 TI - Electron spin resonance of irradiated single crystals of orotic acid. PMID- 4311750 TI - The effects of adrenocorticotrophin hormone and metyrapone on the excretion of urinary steroids by beagle dogs burdened with strontium-90. PMID- 4311751 TI - [Vesicular stomatitis. A survey]. PMID- 4311752 TI - [Electron microscope and experimental investigations on degranulation in tissue mast cells]. PMID- 4311753 TI - [Features of the carcinogenic effect of 3,3'-benzidine dicarboxylic acid]. PMID- 4311754 TI - [Diagnosis of mammary gland tumors by means of radioactive phosphorus]. PMID- 4311755 TI - [Rare forms of ovarian tumors and their treatment]. PMID- 4311756 TI - [ACTH as a prophylactic against the Jarisch-Herxheimer reaction]. PMID- 4311757 TI - [The intra-epidermal epithelioma (so-called Borst-Jadassohn): does this concept constitute an entity in the histopathological sense or not? A histomorphological and histochemical study]. PMID- 4311758 TI - [2 cases of anaphylactic shock after administration of antibiotics]. PMID- 4311759 TI - Histo-enzymological investigations on the muscle fibres of a cephalopode (Octopus vulg. Lam.). PMID- 4311760 TI - Early in-vitro SV40-mediated morphologic transformation of primary hamster cells. Its correlation with the development of the oncogenic state. PMID- 4311761 TI - An ultrastructural study of follicular cells in the human anterior pituitary. PMID- 4311762 TI - An electron microscopic study of the regenerating adrenal gland during the development of adrenal regeneration hypertension. PMID- 4311764 TI - Respiratory viruses. PMID- 4311763 TI - Pathophysiology of epidemic St. Louis encephalitis. I. Inappropriate secretion of antidiuretic hormone. II. Pituitary-adrenal function. 3. Cerebral blood flow and metabolism. PMID- 4311766 TI - Kaposi's varicelliform eruption. Two cases caused by herpesvirus hominis infection complicating Darier's disease. PMID- 4311765 TI - Evaluation of stimulation and suppression tests in the etiological diagnosis of Cushing's syndrome. PMID- 4311767 TI - The neuromuscular blocking action of gentamicin. PMID- 4311768 TI - Simplified feedback in neuromuscular retraining: an automated approach using electromyographic signals. PMID- 4311769 TI - [On the physiopathology of the consumption coagulopathy]. PMID- 4311770 TI - A myocardial sarcolemma preparation and the ouabain-sensitive (Na plus-K plus) ATPase. PMID- 4311773 TI - Nucleoside phosphate levels in normal and tumour cells and their significance. PMID- 4311772 TI - Ribonucleic acid as affected by hepatocarcinogenesis. PMID- 4311771 TI - Pharmacological studies of sleep and dreaming: chemical and clinical relationships. PMID- 4311774 TI - Serum zinc levels in hepatocellular carcinoma. PMID- 4311775 TI - Calculation and measurement of semiconduction activation energy and electron mobility in cytochrome oxidase, with evidence that charge carriers are polarons, which may couple oxidation to phosphorylation. PMID- 4311776 TI - The renal action of angiotensin in rats after expansion of plasma volume or of extracellular fluid. PMID- 4311777 TI - Cardiovascular and respiratory changes during sleep in normal and hypertensive subjects. PMID- 4311778 TI - Variation of killing power of human sera against Bordetella pertussis. PMID- 4311780 TI - The utilization of exogenous pyrimidines and the recycling of uridine-5' phosphate derivatives in Saccharomyces cerevisiae, as studied by means of mutants affected in pyrimidine uptake and metabolism. PMID- 4311779 TI - [Activity of 13 enzymes of intermediary metabolism in livers of young rats recovering from protein malnutrition]. PMID- 4311781 TI - Replication of poliovirus RNA studied by gel filtration and electrophoresis. PMID- 4311782 TI - On the role of quinones in bacterial electron transport. The respiratory system of Bacillus megaterium. PMID- 4311783 TI - Structural investigations on T1 lipopolysaccharides. PMID- 4311784 TI - Chemical synthesis and quantitative estimation of 3-deoxy D-manno-octulosonic acid. PMID- 4311785 TI - Radical formation in cysteamine-HCl gamma-irradiated in the dry state and in frozen aqueous solution. PMID- 4311786 TI - Dream recall in the normal aged. PMID- 4311787 TI - Serum "seromucoid" and physical exercise. PMID- 4311788 TI - Enzymatic synthesis of the antigen carrier lipid. PMID- 4311789 TI - [Application of the fluorescent antibody technic to diagnosis of Japanese encephalitis]. PMID- 4311790 TI - Murine sarcoma and leukemia viruses: assay using clonal lines of contact inhibited mouse cells. AB - A continuous cell line of highly contact-inhibited cells (NIH/3T3) has been developed from NIH Swiss mouse embryo cultures. Its growth properties are similar to those of 3T3 and BALB/3T3. Although 3T3 is relatively insensitive to focus formation by murine sarcoma viruses, cloned lines of both NIH/3T3 and BALB/3T3 have been isolated that are highly sensitive to sarcoma virus focus formation and leukemia virus growth. The sensitivity and specificity are comparable to those found with primary embryo cells. MSV-transformed lines of NIH/3T3 have been obtained. PMID- 4311791 TI - Incorporation of precursors into ribonucleic acid, protein, glycoprotein, and lipoprotein of avian myeloblastosis virions. AB - Freshly explanted leukemic myeloblasts produce avian myeloblastosis virus (AMV) at a constant rate without any obvious cytopathic effect; therefore, subviral components are continually synthesized at a steady rate. The incorporation of various radioactive precursors into virions was monitored by determination of radioactivity in purified virus after density equilibrium sedimentation in preformed sucrose gradients. The kinetics of incorporation of (3)H-uridine have shown that there is an average time interval of 3 to 4 hr (half-life) between the time viral ribo-nucleic acid (RNA) is synthesized and the time it is released as a mature virus particle; this represents the average time interval spent by AMV RNA in an intracellular pool. Studies with (14)C-phenylalanine have revealed that some protein synthesis takes place at or near the cell surface immediately prior to maturation and release of virus. (14)C-glucosamine also appears to be incorporated into the outer viral envelope shortly before maturation. On the other hand, there is an average lag of about 16 to 20 hr before (14)C ethanolamine incorporated into intracellular lipoprotein appears in free virions; this probably reflects the kinetics of replacement of cellular surface membrane. Actinomycin D inhibits AMV-RNA within 30 min but permits the maturation of AMV to continue for at least 2 hr. AMV released in the presence of actinomycin D contains AMV-RNA synthesized before the addition of the drug. PMID- 4311792 TI - Simian virus 40-induced T and tumor antigens. AB - Antigen extracts from simian virus 40 (SV40) transplanted hamster tumors were studied by rate-zonal centrifugation. Three species or molecular forms of antigen were demonstrated. The major antigen component corresponded to a molecular weight of 65,000 to 75,000, and two larger species were detectable in smaller quantities. Similar studies were carried out on SV40 virus-induced T antigen from BSC-1 cells. Three antigen components were again detected. Quantitative differences in the expression of "T" and tumor antigen species were reproducibly found. PMID- 4311793 TI - Properties of simian virus 40 rescued from cell lines transformed by ultraviolet irradiated simian virus 40. AB - Simian virus 40 (SV40) strains have been rescued from various clonal lines of mouse kidney cells that had been transformed by ultraviolet (UV)-irradiated SV40. To learn whether some of the rescued SV40 strains were mutants, monkey kidney (CV 1) cells were infected with the rescued virus strains at 37 C and at 41 C. The SV40 strains studied included strains rescued from transformed cell lines classified as "good," "average," "poor," and "rare" yielders on the basis of total virus yield, frequency of induction, and incidence of successful rescue trials. Four small plaque mutants isolated from "poor" yielder lines and fuzzy and small plaque strains isolated from an "average" and a "good" yielder line, respectively, were among the SV40 strains tested. Virus strains rescued from all classes of transformed cells were capable of inducing the transplantation antigen, and they induced the intranuclear SV40-T-antigen, thymidine kinase, deoxyribonucleic acid (DNA) polymerase, and cellular DNA synthesis at 37 C and at 41 C. With the exception of four small plaque strains rescued from "poor" yielders, the rescued SV40 strains replicated their DNA and formed infectious virus with kinetics similar to parental SV40 at either 37 or 41 C. The four exceptional strains did replicate at 37 C, but replication was very poor at 41 C. Thus, only a few of the rescued virus strains exhibited defective SV40 functions in CV-1 cells. All of the virus strains rescued from the "rare" yielder lines were similar to parental SV40. Several hypotheses consistent with the properties of the rescued virus strains are discussed, which may account for the significant variations in virus yield and frequency of induction of the transformed cell lines. PMID- 4311794 TI - Variation in properties of plaque progeny of PARA (defective simian papovavirus 40)-adenovirus 7. AB - One hundred and twelve progeny from double plaque-purified clones were derived from the original PARA (defective simian papovavirus 40)-adenovirus 7 population. These progeny were found to differ in their oncogenic potential in newborn hamsters with progeny from 20 clones not inducing any tumors during 1 year of observation. The varying tumorigenicity of the individual clonal progeny was not related to the titer of PARA (particle aiding replication of adenovirus) in the inoculum. There was a perfect correlation between the tumor antigen content of the tumor cells and the antibody response of the tumor-bearing host. The tumors containing both adenovirus and simian papovavirus 40 (SV40) tumor antigens appeared earlier than those carrying only SV40 tumor antigen. Progeny from clones which induced mixed tumors also produced tumors which contained only SV40 tumor antigen. Three variants of PARA were isolated which induced the synthesis of SV40 tumor antigen in the cytoplasm of infected simian cells; all other clones yielded progeny which induced synthesis of SV40 tumor antigen in the nucleus. PMID- 4311795 TI - Variants of defective simian papovavirus 40 (PARA) characterized by cytoplasmic localization of simian papovavirus 40 tumor antigen. AB - Three isolates of PARA (particle aiding replication of adenovirus)-adenovirus 7 out of a total of 112 clonal progeny derived by two successive plaque purifications in green monkey kidney cells (GMK) were found to induce the synthesis of simian papovavirus40 (SV 40) tumor (T) antigen in the cytoplasm of infected cells. The variant viruses induced plaque formation in human embryonic kidney cells which followed one-hit kinetics. In GMK cells, plaque formation followed two-hit kinetics which converted to first-order kinetics in the presence of additional helper adenovirus type 7. Analysis of plaque progeny from human cells showed that the progeny could replicate only in human cells, whereas progeny from monkey cells could multiply in both human and monkey cells. Heterologous human adenoviruses were able to enhance plaque formation by the variant viruses in monkey kidney cells. Neutralization tests indicated that both components of the populations had a type 7 adenovirus capsid. All three viruses were capable of inducing SV40 transplantation immunity in weanling hamsters. These results indicate the three variants are PARA-adenovirus 7 populations. Response of the induction of the synthesis of the cytoplasmic antigen to metabolic inhibitors was the same as for the synthesis of the nuclear SV40 T antigen. Different pools of sera which reacted with the intranuclear SV40 T antigen also detected the cytoplasmic antigen induced by the variant viruses. An adsorption experiment with cells containing either nuclear or cytoplasmic T antigen to remove tumor antibody from hamster sera also indicated that it is probably SV40 T antigen which is responsible for the cytoplasmic reaction. The species of the host cell-human, simian, or rabbit-appeared to play no role in the altered localization of this antigen. It is postulated that these PARA variants are further defective in some virus-mediated transport mechanism which shifts the T antigen from the cytoplasm to the nucleus. PMID- 4311796 TI - Host-dependent restriction of mengovirus replication. AB - Mengovirus infection of a restrictive cell line, Maden's bovine kidney (MDBK), results in a virus yield 1,000-fold less than that obtained from productively infected cell lines such as L cells or Ehrlich ascites tumor cells (EAT). Cells of both types of host systems are infected with comparable efficiencies and are completely killed as a consequence of infection. Infective center assays, coupled with the observation of total cell killing, suggest that comparable numbers of cells synthesize viral antigen and release virus in both types of host system. Viral-specific ribonucleic acid (RNA) synthesis is initiated and proceeds in an identical fashion for approximately 4 hr after the infection of MDBK, EAT, or L cells. At this time, viral RNA synthesis in MDBK ceases, whereas viral RNA synthesis in EAT and L-cells continues at a linear rate. These results indicate that none of the early viral events leading to the initiation of viral-specific RNA synthesis constitutes the primary site of mengovirus restriction in MDBK. Rather it appears that the cessation of viral RNA synthesis in restrictive cells constitutes the primary limiting event. Based on its delayed interaction with mengovirus RNA synthesis, it appears that the host-related restrictive agent is initially compartmentalized and then released as a consequence of infection subsequent to those early events in mengovirus infection leading to the initiation and continued synthesis of viral RNA. PMID- 4311797 TI - In vitro transformation by adenovirus-simiam virus 40 hybrid viruses. IV. Properties of clones isolated from cell lines transformed by adenovirus 2-simiam virus 40 and adenovirus 12-simiam virus 40 transcapsidant hybird viruses. AB - Clones were isolated from hamster cells transformed by the adenovirus 2-SV40 and adenovirus 12-SV40 transcapsidant hybrid viruses. The clones were characterized with respect to their cytomorphology, virus and antigen content, and the histomorphology of tumors induced by transplantation of the clonal sublines to hamsters. Three different cellular and colonial morphologies were observed. Clones with an SV40 morphology gave rise to tumors predominantly with an SV40 histology, whereas clones with an adenovirus morphology produced typical adenovirus tumors upon transplantation of the transformed cells. Clones which had features of both SV40 and adenovirus transformed cells gave rise to "intermediate" and adenovirus tumors. The results indicate that multiple events occur during transformation and tumorigenesis by the transcapsidant virus populations and provide an explanation for the multiplicity of findings which have been reported with these virus populations. PMID- 4311798 TI - In vitro transformation by the adenovirus-simian virus 40 hybrid viruses. V. Virus-specific ribonucleic acid in cell lines transformed by the adenovirus 2 simian virus 40 and adenovirus 12-simian virus 40 transcapsidant hybrid viruses. AB - The ribonucleic acid-deoxyribonucleic acid hybridization technique was utilized to determine the presence of adenovirus (ad) and SV40 genetic information and to determine which ad genomes were present in clones of hamster cells transformed with the ad 2-SV40 and ad 12-SV40 transcapsidant hybrid virus populations. The results were correlated with the morphology of the transformed cells and colonies. It was found that cells transformed by either transcapsidant virus which had an SV40 morphology contained the ad 7 and SV40 genomes, whereas cells with a typical ad morphology contained only ad genetic information. Cells and colonies with morphological features of both ad- and SV40-transformed cells contained either the ad 2, or ad 12 genomes, depending on the transcapsidant used, together with the ad 7 and SV40 genomes. The results indicate the following: at least three different events occurred during transformation of hamster cells by the transcapsidant virus populations; the morphology of the resulting clones is determined by the viral genome(s) present; the linkage of the ad 7-SV40 genomes is confirmed since the ad 7- SV40 genomes were never found to be dissociated; the defective ad 7-SV40 genomes are capable of causing transformation; and the transcapsidant particle is probably composed of only ad 7 and SV40 genetic information. PMID- 4311799 TI - Electrophoretic characterization of foot-and-mouth disease virus-specific ribonucleic acid. AB - Foot-and-mouth disease virus (FMDV)-specific ribonucleic acid (RNA) was analyzed by electrophoresis on 0.5% agarose gels. Four classes of RNA were resolved as a function of mobility in agarose: two classes of slowly migrating multistranded RNA, the infectious viral RNA with intermediate mobility, and a minor fast-moving class of lower-molecular-weight single-stranded RNA. The major RNA species were infectious viral RNA and the slowest migrating class of multistranded RNA. The latter RNA was polydisperse when analyzed by sucrose gradient centrifugation, it was partially ribonuclease resistant, and it was the predominant RNA species labeled during the initial period of (3)H-uridine triphosphate incorporation in the cell-free system. Heat treatment studies indicated that part of the slowest moving RNA was degraded at 60 C and almost complete degradation was detected at 100 C. It was concluded that this RNA is the replicative intermediate in viral RNA synthesis. The second class of multistranded RNA contained both a ribonuclease-resistant RNA and a second RNA peak which was detected only after heat treatment at temperatures above 75 C. Fractions of FMDV-specific RNA isolated by sucrose gradient centrifugation were analyzed by agarose-gel electrophoresis. Infectious viral RNA was detected only in the 37S zone and was the major species of RNA in this part of the gradient. The ribonuclease-resistant RNA (the 20S zone) contained about equal amounts of multistranded RNA (both classes) and the low-molecular-weight single-stranded RNA. All sucrose gradient fractions between 20 and 40S were found to contain the replicative intermediate, although the major portion was detected in the 20 to 25S region. PMID- 4311800 TI - Polynucleotide ligase activity in cells infected with simian virus 40, polyoma virus, or vaccinia virus. AB - The conversion of simian virus 40 (SV40) component II deoxyribonucleic acid to component I has been used to assay polynucleotide ligase in extracts of tissue culture cells. All cell types examined, including chicken, hamster, mouse, monkey, and human cells, contained adenosine triphosphate-dependent ligase. After infection of mouse embryo, monkey kidney, and HeLa cells with polyoma virus, SV40, and vaccinia virus, respectively, the enzyme activity increased, but its cofactor requirement was unchanged. In vaccinia virus-infected cells, the increased activity was localized in the cytoplasm. Ligase induction occurred in the presence of cytosine arabinoside but was prevented by puromycin. Rifampicin blocked the production of infectious vaccinia particles but had little effect on the induction of ligase. PMID- 4311802 TI - [Plasma levels of ACTH and cortisol in man during gamma-hydroxybutyrate anesthesia and surgery]. PMID- 4311801 TI - Inhibition of host cell ribosomal ribonucleic acid methylation by foot-and-mouth disease virus. AB - A study of protein and ribonucleic acid (RNA) synthesis in cells infected by foot and-mouth disease virus has indicated possible mechanisms of viral control over host cell metabolism. Foot-and-mouth disease virus infection of baby hamster kidney cells resulted in 50% inhibition of host cell protein synthesis at 180 min postinfection. A viral-induced interference with host cell RNA methylation was observed to be more rapidly inhibited than protein synthesis. To determine the nature of methylation inhibition, the kinetics of several host cell methylated RNA species were examined subsequent to virus infection. Data from sucrose zonal centrifugation and methylated albumin kieselguhr chromatography showed that methylation of nuclear RNA was inhibited 50% at 60 min postinfection. Inhibition of nuclear ribosomal RNA precursors and formation of nascent ribosomes correlated with inhibition kinetics of nuclear RNA methylation. It is suggested that the viral interference with the host nuclear RNA methylation is directly responsible for the observed loss of nascent ribosome formation. Moreover, early in the infectious cycle, methylation inhibition of host cell RNA could, in part, account for the cessation of host protein synthesis. PMID- 4311803 TI - [Angiotensinases]. PMID- 4311805 TI - Insensitivity of mitochondrial RNA synthesis to mengovirus infection in CHO cells. PMID- 4311807 TI - Intraoral minor salivary gland tumors. Report of thirty-eight cases. PMID- 4311804 TI - Initiation of SV40 DNA-directed protein synthesis with N-formylmethionine in vitro. PMID- 4311806 TI - Adenoid cystic carcinoma of the floor of the mouth presenting by metastases. PMID- 4311808 TI - [Time course of skeletal muscle respiration (rat) during contraction]. PMID- 4311809 TI - Behavioral measurement of neural poststimulation excitability cycle: pain cells in the brain of the rat. AB - A new technique in which elicited behavior of the freely moving rat is used to measure the poststimulation excitability cycle of the central neurons mediating that behavior has been adapted from accepted methods of neurophysiology. A continuous train of pairs of brief pulses was delivered to pain systems in the midbrain. Rate of lever pressing to achieve 3-second rests from this stimulation was measured as a function of the interval separating the pulses within pairs. Evidence for latent addition, absolute refractory period, temporal summation, and adaptation was demonstrated. Obtained relationships suggested that three sets of fibers may carry the aversive signal and that synaptic integration of pain in the brain may be related to Stevens' power law functions. PMID- 4311811 TI - Adrenocortical function in patients on long-term corticosteroid treatment. PMID- 4311810 TI - [Neonatal hepatic insufficiency due to anoxia]. PMID- 4311812 TI - [The so-called alveolar soft part sarcoma interpreted as a prelipoblastoma]. PMID- 4311813 TI - [For the differentiation between dysontogenetic cysts and retention cysts of the vocal cords]. PMID- 4311814 TI - Preparation of ribosome-free membranes from rat liver microsomes by means of lithium chloride. AB - 1. Treatment of washed rat liver microsomes in a medium containing 0.12m-sucrose, 12.5mm-potassium chloride, 2.5mm-magnesium chloride and 25mm-tris-hydrochloric acid buffer, pH7.6, with 2m-lithium chloride at 5 degrees for 16hr. leads to the formation of membranes free of ribosomes and ribosomal subunits. 2. Confirmation of the absence of ribosomes from lithium chloride-prepared membranes was obtained by treatment of the membranes with sodium deoxycholate, followed by sucrose density-gradient centrifugation, which showed the complete absence of ribosomes. 3. Treatment of membranes with phenol, followed by sucrose-density-gradient analysis of the isolated RNA, showed the presence of a small amount of 4s material. Repetition of the phenol extraction procedure in the presence of liver cell sap as a ribonuclease inhibitor again showed the presence of only 4s material. The 4s RNA was shown to be transfer RNA by the fact that it had the same capacity for accepting (14)C-labelled amino acids as isolated transfer RNA from rat liver pH5 enzyme. 4. Analysis showed that microsomes and membranes possessed similar glucose 6-phosphatase, NADH-2,6-dichlorophenol-indophenol reductase, NADH-neo-tetrazolium reductase, NADH-cytochrome c reductase and ribonuclease activities. 5. (3)H-labelled ribosomal RNA binds to membranes. However, isolation of the bound RNA by the phenol extraction procedure, followed by sucrose-density-gradient analysis, shows the RNA to be degraded to 7s material. Very little breakdown of (3)H-labelled ribosomal RNA bound to membranes occurs if the binding and isolation are carried out in the presence of liver cell sap. PMID- 4311815 TI - The hormonal control of protein synthesis. PMID- 4311816 TI - Localization of N-acetyl-beta-glucosaminidase on rat liver membranes. PMID- 4311817 TI - Enzyme distributions in an amoeba during encystment. PMID- 4311818 TI - Lipolytic activity in the pancreas. PMID- 4311819 TI - Lysosomes in hepatomas. PMID- 4311820 TI - Interaction of salicylates with rat liver lysosomes. PMID- 4311821 TI - The metabolism of nicotinamide-adenine dinucleotide in various classes of rat liver nuclei. PMID- 4311822 TI - Subcellular fractionation of Saccharomyces carlsbergensis by zonal centrifugation. PMID- 4311823 TI - The haem--protein interaction in cytochrome P-450. PMID- 4311825 TI - Structural studies on colanic acid, the common exopolysaccharide found in the enterobacteriaceae, by partial acid hydrolysis. Oligosaccharides from colanic acid. AB - The exopolysaccharide slime colanic acid has been isolated from representative strains of Escherichia coli, Salmonella typhimurium and Aerobacter cloacae. Analysis showed that each polymer contained glucose, galactose, fucose and glucuronic acid, together with acetate and pyruvate. The molar proportions of these components were 1:1.8:1.9:1:1:1 approximately. On the basis of periodate oxidation of the natural and deacetylated polysaccharide, glucose is proposed as the site of the acetyl groups. The pyruvate is attached to galactose. Three neutral oligosaccharides and ten electrophoretically mobile oligosaccharides were isolated and partially characterized. Four of the fragments were esters of pyruvic acid. Most oligosaccharides were isolated from all three polysaccharide preparations. Three further oligosaccharides were isolated from carboxyl-reduced colanic acid and sodium borotritide was used to label the glucose derived from glucuronic acid in these fragments. One trisaccharide was obtained from periodate oxidized polysaccharide. On the basis of these oligosaccharides a repeating hexasaccharide unit of the following structure is proposed: [Formula: see text] The significance of this structure in colanic acid biosynthesis is discussed. PMID- 4311824 TI - The synthesis of nicotinamide-adenine dinucleotide and poly (adenosine diphosphate ribose) in various classes of rat liver nuclei. AB - 1. The activities of NMN adenylyltransferase and an enzyme that synthesizes poly (ADP-ribose) from NAD were investigated in the various classes of rat liver nuclei fractionated by zonal centrifugation. 2. The highest specific activities of these two nuclear enzymes occur in different classes of nuclei. In very young and in mature rats it was shown that a correlation exists between DNA synthesis and NMN adenylyltransferase activity, but in rats of intermediate age this correlation is less evident. The highest activities of the enzyme that catalyses formation of poly (ADP-ribose) are in the nuclei involved in the synthesis of RNA. 3. The significance of these results in relation to NAD metabolism is discussed. PMID- 4311826 TI - The metabolism of D-glucarate by Pseudomonas acidovorans. AB - 1. Dehydratases that converted d-glucarate into 4-deoxy-5-oxoglucarate were partially purified from Klebsiella aerogenes and Pseudomonas acidovorans. 2. When d-glucarate was metabolized to 2,5-dioxovalerate it appeared that water and carbon dioxide were removed from 4-deoxy-5-oxoglucarate in one enzymic step: 4,5 dihydroxy-2-oxovalerate was not an intermediate in this reaction. 3. A method for the enzymic determination of d-glucarate is described. PMID- 4311827 TI - Influence of insulin on cyclic 3',5'-AMP phosphodiesterase activity in liver, skeletal muscle, adipose tissue, and kidney. PMID- 4311829 TI - [Effects of angiotensin on the peripheral circulation in normal and hypertensive subjects]. PMID- 4311828 TI - Effects of glucocorticoids and insulin on 3',5'-AMP phosphodiesterase activity in adrenalectomized rats. PMID- 4311830 TI - [Neuropathies of subacute development during serious pulmonary tuberculosis]. PMID- 4311831 TI - [Polygraphic study of night sleep in a chronic alcoholic in withdrawal]. PMID- 4311832 TI - [Structural flexibility and enzyme function]. PMID- 4311833 TI - Demonstration of N-acetyl-D-galactosamine in tumor cells by the immunofluorescence technic. PMID- 4311835 TI - [Activity of the hypothalamo-hypophyseal-adrenal system and of certain metabolic regulatory mechanisms in early acute disorders of the brain]. PMID- 4311834 TI - The major hydrocarbon of a cockroach cuticular wax. PMID- 4311836 TI - [Intravenous infusion of angiotensin following surgical treatment of arterial hypertension]. PMID- 4311837 TI - [Peripheral neuropathy combined with chronic renal insufficiency]. PMID- 4311838 TI - An improved adenosine triphosphatase assay for physical particles of avian myeloblastosis virus (AMV). PMID- 4311839 TI - Characterization of tumor-specific transplantation immunity reactions in immunodiffusion chambers in vivo. PMID- 4311840 TI - Neoplastic transformation and derivation of a focus-forming sarcoma virus in cultures of rat embryo cells infected with a murine osteosarcoma (FBJ) virus. PMID- 4311841 TI - Effects of cations and organic compounds on inactivation of poliovirus with urea, guanidine, and heat. PMID- 4311842 TI - Influence of angiotensin II on the systemic and pulmonary circulations of intact anesthetized dogs. PMID- 4311843 TI - A simple chemical method for the measurement of plasma angiotensin. PMID- 4311844 TI - Inhibition of Friend virus-induced splenomegaly by an associated lymphatic leukemia virus. PMID- 4311845 TI - Investigations on a tissue antagonist of interferon (TAI). PMID- 4311846 TI - Isolation of cytomegalovirus from a cohort of 100 infants throughout the first year of life. PMID- 4311847 TI - Propagation of mammalian viruses in protista. IV. Experimental infection of C. albicans and S. cerevisiae with polyoma virus. PMID- 4311848 TI - Cell-mediated complementation of human adenoviruses by simian papovavirus. PMID- 4311849 TI - [Changes of post-synaptic activity of the neurons of the lateral geniculate nucleus following diffuse retinal stimulation]. PMID- 4311850 TI - [Peripheral neuropathy in hypothyroidism: electromyographic considerations]. PMID- 4311851 TI - [Clinical and electroencephalographic correlations in 90 pituitary adenomas]. PMID- 4311852 TI - [Generalized herpes simplex changing into the clinical picture of erythema exsudativum multiforme (herpetid)]. PMID- 4311853 TI - [Stromal mastocytosis of viral-induced transplantable adenocarcinomas of the rat]. PMID- 4311854 TI - [The antibicrobical action of new aminoguanidones]. PMID- 4311855 TI - [Studies on precipitation, ion exchange chromatography and electrophoretic mobility of tissue-culture viruses in the presence of water soluble linear polycondensation and polymerisation products]. PMID- 4311856 TI - Detection and separation of simultaneous Enterovirus and intestinal Chlamydia infection of calves. PMID- 4311857 TI - [Compatibility of hypertension and halothane]. PMID- 4311858 TI - Effect of treatment on tryptophan metabolism in childhood epilepsy. PMID- 4311859 TI - Coexistence of antibodies against chronic respiratory disease, infectious laryngotracheitis, and infectious bronchitis on poultry farms of Uttar Pradesh, Andhra Pradesh, and Madras. PMID- 4311860 TI - Celo virus infection in chickens: clinical and serological response to experimental and accidental infection. PMID- 4311861 TI - Marek's disease herpesvirus: in vivo and in vitro infection of kidney cells of different genetic strains of chickens. PMID- 4311862 TI - Serum albumin production by hepatoma cells in culture: direct evidence for stimulation by hydrocortisone. PMID- 4311863 TI - The enzymatic phosphorylation of sphinganine. PMID- 4311864 TI - No effect of guanidine on an improved in-vitro system for viral RNA polymerase. PMID- 4311865 TI - On the problem of efficient antibiotic therapy of infections caused by Pseudomonas aeruginosa. PMID- 4311866 TI - Management of foot drop in adults after permanent peroneal nerve loss. PMID- 4311867 TI - Regulation of the formation of acid phosphatases by inorganic phosphate in Aspergillus ficuum. AB - Two types of extracellular acid phosphatases are synthesized by Aspergillus ficuum NRRL 3135: a nonspecific orthophosphoric monoester phosphohydrolase (EC 3.1.3.2) with an optimum pH of 2.0, and an enzyme with restricted specificity, a mesoinositol-hexaphosphate phosphohydrolase (EC 3.1.3.8; phytase) with an optimum pH of 5.5. Although the pH 5.5 enzyme is termed a phytase, both enzymes hydrolyze phytin. Synthesis of the enzymes is repressed by high orthophosphate concentrations in the fermentation medium. The highest total level for each enzyme is synthesized in low orthophosphate medium. In high orthophosphate medium, more pH 5.5 enzyme is produced than pH 2.0 enzyme. In low orthophosphate medium, more pH 5.5 enzyme is produced than pH 2.0 enzyme during the early stages of growth, but the reverse occurs after 5 days. The enzymes are differentiated by heat denaturation at acid and alkaline pH levels. They are separated into two distinct fractions on Sephadex G-100 followed by carboxymethylcellulose column chromatography. This indicates that the two enzymes are structurally different. The K(m) for both enzymes is 1.25 mm when calcium phytate is the substrate. Orthophosphate competitively inhibits the pH 2.0 (K(i) = 1.1 x 10(-2)m) but not the pH 5.5 phosphatase. Neither enzyme is denatured by 50% (w/v) urea or inhibited by 0.01 m tartrate. Thus, they differ from human prostatic phosphatase. PMID- 4311868 TI - Carbohydrate transport in Clostridium perfringens type A. AB - Resting-cell suspensions of Clostridium perfringens actively transported glucose and mannose but not six other carbohydrates which would support at least limited growth of the microorganism. Competition studies suggested that glucose and mannose were transported by a common mechanism which was highly specific. Analyses of intracellular pools demonstrated that the accumulated carbohydrates were present as phosphorylated derivatives, not as free carbohydrates, and specificity data indicated that phosphorylation occurred at the transport level rather than via the soluble hexokinase. PMID- 4311869 TI - Streptolydigin, an inhibitor of oxidative phosphorylation in rat liver mitochondria. AB - Streptolydigin interferes with oxidative phosphorylation in rat liver mitochondria. The agent acts primarily as an uncoupler of respiration-associated phosphorylation but also impairs respiration to various degrees depending on the substrate. Streptolydigin partially inhibits electron flow at a point past the cytochrome b and prior to the cytochrome c reduction site. Streptolydigin also inhibits the function of the enzyme ribonucleic acid polymerase in whole bacterial cells and cell-free systems. The streptolydigin concentrations that cause effective inhibition of ribonucleic acid polymerase in cell-free systems are approximately 10 times less than those required to inhibit oxidative phosphorylation in mitochondria. PMID- 4311870 TI - Phosphorylation of methyl-alpha-D-glucopyranoside in polymyxin B-treated Salmonella typhimurium. AB - Phosphoenolpyruvate-dependent phosphorylation of methyl-alpha-d-glucopyranoside in Salmonella typhimurium is increased by the membrane active polypeptide antibiotic polymyxin B whereas active transport ability is abolished. PMID- 4311871 TI - Glucose degradation in Clostridium perfringens type A. AB - Cell-free extracts of Clostridium perfringens were found to contain all the enzymes of the Embden-Meyerhof pathway of glycolysis in addition to lactic acid dehydrogenase and the pyruvate-clastic system. Neither glucose-6-phosphate dehydrogenase nor 6-phosphogluconate dehydrogenase activities could be demonstrated, suggesting the absence of the conventional hexose-monophosphate pathway in this organism. PMID- 4311872 TI - Transfer RNA from tumor tissue. PMID- 4311874 TI - Pink cell (oncocytic) metaplasia in a fibro-adenoma of the human breast: electron microscope observations. PMID- 4311873 TI - An enzyme histochemical study of some dehydrogenases in abnormal human mammary tissue. PMID- 4311875 TI - Changes in the reactivity of the skin blood vessels of the rabbit with age. PMID- 4311876 TI - Natural selection of long-lived macrophages in experimental granulomata. PMID- 4311877 TI - Early morphological and histochemical consequences of peripheral nerve section in lambs of normal and low copper status. PMID- 4311878 TI - An electrophysiological study of the innervation of the smooth muscle of the colon. AB - 1. Micro-electrodes were used to examine transmission from intrinsic and extrinsic nerves to single cells of the longitudinal and circular muscle coats of colons from guinea-pigs and rabbits.2. When intrinsic nerves were stimulated, inhibitory junction potentials (IJPs) were observed in over 90% of the cells of the longitudinal coat and nearly all of the cells of the circular coat. The characteristics of IJPs in the guinea-pig and rabbit were similar. Facilitation of two or three successive IJP's was sometimes observed. The IJPs were unaffected by guanethedine but were blocked by procaine. IJPs could not be elicited by stimulation of either the pelvic parasympathetic or periarterial sympathetic nerves. In some cells, the IJP was preceded by a brief depolarization, which probably results from the stimulation of excitatory nerves to the same cell.3. Excitatory junction potentials (EJPs) were observed in about 5% of cells of the longitudinal coat in response to stimulation of the intramural nerves. When the pelvic nerves were stimulated, EJPs were observed in most cells of both the longitudinal and circular muscle coats. The EJP in the guinea-pig colon was blocked by hyoscine.4. The interaction of the IJP evoked by intrinsic nerve stimulation and the EJP evoked by pelvic nerve stimulation was examined. When both nerve supplies were stimulated together, only an IJP was observed.5. The nature of the innervation of the colon and the origin of intrinsic non-adrenergic inhibitory neurones is discussed. PMID- 4311880 TI - Insulin biosynthesis and secretion--a still unsettled topic. PMID- 4311879 TI - Transmission from vasoconstrictor and vasodilator nerves to single smooth muscle cells of the guinea-pig uterine artery. AB - 1. Previous studies have shown that perivascular nerve stimulation of the uterine artery of the guinea-pig evokes an adrenergic constrictor response and a dilator response with two components. The first of these, only present during pregnancy, is cholinergic. The second is non-cholinergic and is present at all times. Intracellular recording from single smooth muscle cells in isolated arterial segments has now been used to investigate the transmission processes associated with these responses.2. The mean resting membrane potential of the muscle cells was 60.7 mV in arteries from both virgin animals (range 50-68 mV) and from animals in late pregnancy (range 48-76 mV).3. Low frequency perivascular stimulation evoked excitatory junction potentials (EJPs) which reached a maximum amplitude of about 5 mV, lasted about 900-1000 msec, and showed facilitation at frequencies of stimulation of 0.1 Hz or above and summation at frequencies of stimulation of 1.2 Hz or above.4. These EJPs were abolished by exposure of the tissue to bretylium (2 x 10(-6) g/ml.). It is therefore concluded that the EJPs were due to transmission from adrenergic nerves.5. Perivascular stimulation at frequencies above 10 Hz evoked a depolarizing response which was often surmounted by a small (5 mV) local spike potential. Such depolarizing responses were associated only with localized contractions of the arterial muscle.6. In the presence of low extracellular K(+) concentrations, perivascular stimulation at frequencies above 10 Hz gave rise to a depolarizing response topped by an action potential of up to 50 mV amplitude, and more generalized contraction of the tissue than was seen in normal K(+) solution.7. After blockade of the adrenergic vasoconstrictor fibres, no response to perivascular stimulation was observed normally. However, following moderate depolarization of the membrane with noradrenaline, stimulation evoked a hyperpolarization of up to 6 mV in amplitude.8. This response showed no discrete junction potentials, had a latency of up to 2000 msec and was only observed with stimulation at frequencies of 2 Hz or greater. The response was obtained in both pregnant and non-pregnant animals, and was unaffected by hyoscine, but was abolished by cinchocaine.9. No changes in membrane potential attributable to transmission from cholinergic dilator nerves could be revealed in arteries from pregnant animals. Furthermore, high concentrations of acetylcholine had no polarizing effect on the muscle cells. It is suggested that the cholinergic dilator nerves may not act via changes in membrane potential. PMID- 4311881 TI - Adrenocorticotrophic-hormone deficiency in chronic myelogenous leukemia after treatment. PMID- 4311882 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 4-1970. PMID- 4311883 TI - Trigeminal sensory neuropathy and bell's palsy. PMID- 4311884 TI - Diagnosis and treatment of trophoblastic disease. A report from the Southeastern Regional Center. PMID- 4311885 TI - Carcinoma of the vulva. Influence of radical operation on cure rate. PMID- 4311886 TI - Antigens of virus-induced tumors. PMID- 4311888 TI - Sleep loss and cerebral excitability. PMID- 4311887 TI - Action of curare and magnesium on striated muscle of stress-susceptible pigs. PMID- 4311889 TI - Dynamics of uterine circulation in pregnant and nonpregnant sheep. PMID- 4311890 TI - Effects of changes in serum calcium on hypocalcemic response to thyrocalcitonin in the rat. PMID- 4311891 TI - Automated measurement of phosphatases. PMID- 4311892 TI - Anaerobic reductive titrations with solid diluted sodium dithionite in an apparatus suitable for EPR spectroscopy. PMID- 4311894 TI - Atypical pneumonia in young men with rhinovirus infections. PMID- 4311893 TI - Potential medical problems in personnel returning from Vietnam. PMID- 4311895 TI - Unusual clinical manifestations and angiographic findings in a patient with the Zollinger-Ellison syndrome. PMID- 4311896 TI - The fibrinogen-fibrin system in human intracranial tumor tissues: an immunohistological study. PMID- 4311898 TI - New in psychiatry. Moditen injectable therapy and follow-up care. PMID- 4311897 TI - Fractionation of deoxyribonucleic acid from multiple-drug-resistant staphylococci on poly-L-lysine-kieselguhr columns. PMID- 4311899 TI - The role of cyclic AMP in the control of carbohydrate metabolism. PMID- 4311900 TI - Significance of human plasma insulin Sephadex fractions. PMID- 4311901 TI - Effects of prostaglandin E-1 on the hypothalamo-hyophyseal-adrenocortical axis in rats. PMID- 4311902 TI - Effects of thyroid hormones on the guinea pig. PMID- 4311903 TI - Absorption and conjugation of metyrapone during diphenylhydantoin therapy: mechanism of the abnormal response to oral metyrapone. PMID- 4311904 TI - Production of steroids by in vitro superfusion of endocrine tissue. II. Steroid output from bisected whole, capsular and decapsulated adrenals of normal intact, hypophysectomized and hypophysectomized-nephrectomized rats as a function of time of superfusion. PMID- 4311905 TI - Enzymatic activities of cortisol hydroxylation at C-2a and C-6 beta in liver, adrenal and spleen homogenates of L2C-NB leukemia-bearing guinea pigs. PMID- 4311906 TI - Iodine metabolism in thyroid slices: effects of TSH, dibutyryl cyclic 3',5'-AMP, NaF and prostaglandin E-1. PMID- 4311907 TI - Failure of "bound insulin" to affect glucose metabolism of brown fat cells. PMID- 4311909 TI - Effects of ACTH and an inhibitor of 3 beta-hydroxysteroid dehydrogenase on the synthesis of adrenocortical mitochondrial proteins. PMID- 4311908 TI - Acute effects of adrenocorticotropin on the levels of various lipids in the adrenals of hypophysectomized rats. PMID- 4311910 TI - Determination of elastolytic activity with 125-I and 131-I labelled elastin. PMID- 4311911 TI - Uridine diphosphoacetylglucosamine pyrophosphatase activity during connective tissue growth. PMID- 4311912 TI - Hydrolysis of condensed phosphates by a partially purified phosphatase from cactus phylloclades. PMID- 4311913 TI - A study of the mechanism of electron transfer in cytochrome c. Chromium as a probe. PMID- 4311914 TI - Studies on cytochrome c peroxidase. XVI. Recombination of apoenzyme with spin labeled protoheme. PMID- 4311915 TI - Studies on poly adenosine diphosphate-ribose. VII. Methods of separation and identification of 2'-(5"-phosphoribosyl)-5'-adenosine monophosphate, ribosyladenosine monophosphate, and phosphoribosyladenosine. PMID- 4311917 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. XX. Characterization of ASU-particles. PMID- 4311916 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. XIX. Purification and characterization of a new coupling factor (F5). PMID- 4311918 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. XXI. Resolution of submitochondrial particles from bovine heart mitochondria with silicotungstate. PMID- 4311919 TI - Electron paramagnetic resonance study of the stereochemistry of nitrosylhemoglobin. PMID- 4311920 TI - Derivatives of 2,3,4,5,6-penta-O-benzyl-myo-inositol. PMID- 4311921 TI - Studies on Japanese B encephalitis virus vaccines from tissue culture. X. Characterization of a 37 degreeC passage line attenuated strain of OCT-541 virus. PMID- 4311922 TI - [ATP citrate lyase]. PMID- 4311923 TI - A histochemical study of enzyme changes and ultrastructure of the jejunal mucosa in protein-depleted rats. PMID- 4311924 TI - Reactions to a questionnaire survey: some sources of respondent resistance. PMID- 4311925 TI - Electron microscopic changes in mitochondria of the intestinal epithelium and the liver in mice and D-avitaminotic rats after peroral distribution of sodium fluoride. PMID- 4311926 TI - [Plasma levels of ACTH and cortisol in man during halothane anesthesia and surgery]. PMID- 4311927 TI - [Biochemistry of the erythrocyte, with special reference to glycolytic enzymes]. PMID- 4311929 TI - In vivo replication of normal and tumor cells: relation to cancer chemotherapy. PMID- 4311928 TI - Cochlear blood flow in response to vasodilating drugs and some related agents. PMID- 4311930 TI - Control of the reversion of properties in transformed cells. PMID- 4311931 TI - Chemospecific synaptic repression as a possible memory store. PMID- 4311932 TI - Translation of RNA from encephalomyocarditis virus in a mammalian cell-free system. PMID- 4311934 TI - Spin-label study of the iodine-lecithin interaction. PMID- 4311933 TI - Stimulation by cyclic AMP of intrinsic protein kinase activity in ox brain membrane preparations. PMID- 4311935 TI - Cyclic 3',5'-AMP and uterine contractility. PMID- 4311936 TI - Salivary gland enlargement and functional changes during feeding of pancreatin to rats. (Possible relation to functional changes in cystic fibrosis). PMID- 4311937 TI - Some recent neurophysiological contributions to the problem of brain and behavior. PMID- 4311938 TI - Proinsulin and the biosynthesis of insulin. PMID- 4311939 TI - Metabolic events associated with steroid hydroxylation by the adrenal cortex. PMID- 4311940 TI - [Infections caused by respiratory viruses in children of Sao Paulo. II. Adenovirus: isolation and serological study]. PMID- 4311941 TI - [Neuromyopathy and atypical cutaneous syndrome associated with cancer of the esophagus]. PMID- 4311942 TI - [Jean Fernel, unsuccessful reformer of the medicine of the Renaissance]. PMID- 4311943 TI - [Hormone therapy of eye diseases (review of the literature)]. PMID- 4311945 TI - [Masculinizing ovarian tumor (ovarian arrhenoblastoma)]. PMID- 4311944 TI - [Histological and histochemical aspects of osteogenesis in chick embryos treated with parathyroid hormone]. PMID- 4311946 TI - [Estimation of the binding capacity of cortisol on plasma proteins (transcortin) by filtration on sephadex gel (results in the normal subject)]. PMID- 4311947 TI - [Therapeutic possibilities in tracheal tumors]. PMID- 4311948 TI - [Opacification of the internal auditory tube. In case of what unilateral perception hypoacousia is it justified?]. PMID- 4311949 TI - [Congenital megatrachea with dyskinesia]. PMID- 4311951 TI - [Therapeutic action of a new antibiotic-corticoid association used for instillations in otology]. PMID- 4311950 TI - [Gentamicin and auricular toxicity]. PMID- 4311952 TI - [Characteristics of RNA synthesized in the presence of actinomycin D in mouse plasmacytoma]. PMID- 4311953 TI - [Sporadic cases of pharyngo0conjunctival fever and follicular conjunctivitis in Eastern Slovakia in the year 1962-1968]. PMID- 4311954 TI - [Suppurative lymphadenitis of the cervical lymph nodes caused by Pseudomonas aeruginosa in a 15-year-old boy]. PMID- 4311955 TI - [Bordetella pertussis as an immunological adjuvant]. PMID- 4311956 TI - [Effect of Clomid on the activity of microsomal NAD-specific 17beta hydroxysteroid dehydrogenase in the liver of infantile female guinea pigs]. PMID- 4311957 TI - [Action of antiviral antibodies on some viruses isolated from patients with infectious hepatitis]. PMID- 4311958 TI - [Fibrinolytic activity of the toxins of Cl. perfringens, Cl. oedematiens and Cl. septicum in mono- and mixed gas infection]. PMID- 4311959 TI - [On Wiedemann-Beckwith syndrome. First Italian case]. PMID- 4311960 TI - [A case of non-hereditary odontogenesis imperfecta]. PMID- 4311961 TI - [Nephrotic syndrome during thyreostatic treatment with sodium perchlorate]. PMID- 4311962 TI - [The gastro-camera in stomach diagnosis]. PMID- 4311963 TI - The development of the cerebellum of vertebrates in relation to the control of movement. PMID- 4311964 TI - Activation of glutathionase in rat liver during carcinogenesis. PMID- 4311965 TI - [Nuclear margin changes in herpes simplex virus-infected HeLa cells]. PMID- 4311966 TI - Dry mass of human viruses, as determined by quantitative electron microscopy. PMID- 4311967 TI - [Neurology in hippocratic medicine. Overview]. PMID- 4311968 TI - [The use of conjugated estrogens in ophthalmology]. PMID- 4311969 TI - [Treatment of chronic destructive forms of pulmonary tuberculosis with drugs of the second series in different combinations]. PMID- 4311970 TI - [Clear cell hidradenoma]. PMID- 4311971 TI - [On the state of contamination of meat products for sale in the city of Modena with Cl. perfringens of an "enterotoxic" type]. PMID- 4311972 TI - [Studies of the presence of fecal carriers of Cl. pe fringens of an "enterotoxic" type in the healthy population of the city of Rimini]. PMID- 4311973 TI - [On the presence of fecal carriers of "enterotoxic" Cl. perfringens in groups of food handlers and of healthy subjects examined at home]. PMID- 4311974 TI - [The pathogenesis of odontogenic infection]. PMID- 4311975 TI - [Hormone examination in children with Klinefelter's syndrome]. PMID- 4311976 TI - [Pediatric guiding principles: 28. Urinary tract infection]. PMID- 4311977 TI - [Electrokymography in the dispensary care of patients with myocardial infarct]. PMID- 4311978 TI - [Salivary gland neoplasms at rare locations]. PMID- 4311979 TI - [Factors participating in the formation of Cl. perfringens BP6K alpha-toxin in media of determined chemical composition. I. The mechanism of the stimulating effect of an excess of arginine on toxin formation]. PMID- 4311980 TI - [The effect of proteolytic enzymes on the activation of the prototoxins of Cl. perfringens types D and E]. PMID- 4311981 TI - [An electron microscopic study of the fine structure of toxigenic and weakly toxigenic strains of Cl. perfringens]. PMID- 4311982 TI - [Effect of endocrine system on the permeability of the hematolabyrinthine barrier]. PMID- 4311983 TI - Chromophobe adenomas of the pituitary gland in Cushing's disease. PMID- 4311984 TI - The growth of the ventral prostate, the dorsolateral prostate, the coagulating glands and the seminal vesicles in castrated male rats injected with ACTH and-or insulin. PMID- 4311985 TI - Studies on the mode of action of alpha-methyldopa. PMID- 4311986 TI - An automated fluorometric alkaline phosphatase microassay with 4 methylumbelliferyl phosphate as a substrate. PMID- 4311987 TI - Cardiopulmonary function in uranium miners. PMID- 4311988 TI - Cellular aspects of the control of physiological color changes in crustaceans. PMID- 4311989 TI - Cellular aspects of the control of physiological color changes in fishes. PMID- 4311990 TI - Cellular aspects of the control of physiological color changes in amphibians. PMID- 4311991 TI - Physiological color changes in reptiles. PMID- 4311992 TI - Benign tumors of lung and tracheobronchial tree. PMID- 4311993 TI - Granular cell myoblastoma of the larynx. PMID- 4311994 TI - Granular cell myoblastoma of the tongue. PMID- 4311995 TI - Ion-dependent activation and inhibition of ribonucleotide reductase from Lactobacillus leichmannii. PMID- 4311996 TI - Phosphate and mannose transfer from guanosine diphosphate mannose to yeast mannan acceptors. PMID- 4311997 TI - Congenital cytomegalovirus infection: clinical, pathological and virological studies of two fatal cases. AB - Two infants severely ill at birth as a result of congenital cytomegalovirus infection were born in Halifax, Nova Scotia, in April and July 1968. Both died within seven weeks. Clinical, pathological and virological studies including serology and electron microscopy were made both before and after death. Cytomegalovirus was isolated in tissue culture from urine specimens from both infants during life and from organ tissues, blood and ascitic fluid after death. Large inclusion-bearing cells mixed with the erythrocytes and leukocytes were seen within the lumina of pulmonary blood vessels. A brief general discussion is presented of the various clinical manifestations of congenital cytomegalovirus infection and of the different serum antibody patterns found in these two pairs of mothers and infants. PMID- 4311999 TI - [The role of antiviral chemotherapy in dentistry]. PMID- 4311998 TI - Prevalence of cytomegalovirus infection in a normal urban population in Nova Scotia. AB - During 1967 and 1968 a seroepidemiological survey was conducted on the prevalence of CF antibodies to CMV in the normal population of the Halifax-Dartmouth metropolitan area of Nova Scotia. Samples of 550 sera, collected from all age groups, including newborns, were processed. At birth, 34% of infants possess antibodies, presumably of maternal origin, and there follows a decline until at 2 years of age only 4% of children exhibit evidence of infection. There is a gradual increase up to 16% by 20 years of age, and thereafter this is maintained until by 40+ years half the population possesses antibodies.A more detailed analysis of cord sera indicated that approximately 60% of women of childbearing age possess no antibodies and are susceptible to primary CMV infection. Among these, age and gravidity are not significant factors.These data indicate that CMV infection is fairly widespread in this community, although comparative studies suggest that it is less so than in some other areas, such as Easter Island, where a more homogeneous pattern of overcrowding and poor sacioeconomic conditions prevails. PMID- 4312000 TI - Positive inotropic effects of dibutyryl cyclic adenosine 3',5'-monophosphate. PMID- 4312001 TI - [Electromyography and speed of motor conduction in nerve compression]. PMID- 4312002 TI - Susceptibility of dinucleotides bearing either 3'- or 5'-monophosphate to micrococcal nuclease. PMID- 4312003 TI - Alterations in the characteristics of sugar uptake by mouse cells transformed by murine sarcoma viruses. PMID- 4312004 TI - Cerebral gigantism: concentrations of amino acids in plasma and muscle. PMID- 4312005 TI - Cell size, macromolecule composition, nuclear number, oxygen consumption and cyst formation during two growth phases in unagitated cultures of Acanthamoeba castellanii. PMID- 4312006 TI - Interaction of acetylcholine with different cholinergic nerve receptors. PMID- 4312007 TI - Windborne dispersal of foot and mouth virus. PMID- 4312008 TI - Suppression of pituitary-adrenal function with physiological plasma levels of corticosterone. PMID- 4312009 TI - The effect of a CRF preparation on ACTH release in rats bearing hypothalamic dexamethasone implants: a study on the "implantation paradox". PMID- 4312010 TI - Vincristine therapy in an infant with probable hepatoblastoma. PMID- 4312011 TI - Hereditary adrenocortical unresponsiveness to ACTH. PMID- 4312012 TI - Antibiotic guidelines for hand infections. PMID- 4312013 TI - Angiographic investigations in portal hypertension. PMID- 4312014 TI - Effects of ovariectomy and hypervitaminosis A on lysosomes of the rat conceptus. PMID- 4312016 TI - [Carnosine and anserine formation in tumors in vitro]. PMID- 4312015 TI - [Renewal intensity of phospholipid phosphorus in pigeon pectoral muscle]. PMID- 4312017 TI - Prophylaxis and treatment of endemic goiter with iodized oil in rural Ecuador and Peru. PMID- 4312018 TI - Angiofibromatous polyp of the pharynx. PMID- 4312019 TI - Retention of differentiated function in clonal animal cell lines, particularly hormone-secreting cultures. PMID- 4312020 TI - Isolation and partial characterization of beef heart proteolipid. PMID- 4312021 TI - Lipid-iodine association in the rat thyroid gland. PMID- 4312023 TI - [Electron spin resonance studies of radiation-induced radicals of alpha-D glucose, beta-D-glucose and D-glucuronic acid]. PMID- 4312022 TI - [Electron spin resonance spectroscopy of some radiation-induced free radicals of DL-valine, N-acetyl-DL-valine and glycyl-DL-valine]. PMID- 4312024 TI - [Subcalcaneum exostosis and decompression of the tarsal canal (9 cases)]. PMID- 4312025 TI - Vincristine sulfate and radiation therapy in metastatic Wilms' tumor. PMID- 4312026 TI - Ultrastructure of adenoid cystic carcinoma. PMID- 4312027 TI - Wilms' tumor in an adult. PMID- 4312028 TI - Radiation-induced skin cancer of the head and neck. PMID- 4312029 TI - Hemorrhagic cystitis and cytomegalic inclusions in the bladder associated with cyclophosphamide therapy. PMID- 4312030 TI - Intracellular recording in extensor motoneurons of spastic cats. PMID- 4312031 TI - Characteristics of the reaction between diphtheria toxin, pyridine coenzymes and the GTP-splitting transfer factor FI. PMID- 4312033 TI - Inhibition of tumor growth by nucleoside cyclic 3'-5'-monophosphates. PMID- 4312032 TI - The use of synthetic substrates for the determination of mammalian collagenases. Is collagenolytic activity present in mitochondria? PMID- 4312034 TI - Carbohydrate metabolism in experimental Bacillus Calmette-Guerin infection. PMID- 4312035 TI - The molecular structure of SV40 virions. PMID- 4312036 TI - Multiple forms of D (-)3-hydroxybutyrate dehydrogenase in Rhizobium. PMID- 4312037 TI - Internal components of adenovirus. PMID- 4312038 TI - Fate of adenovirus during the early phase of infection. PMID- 4312039 TI - Egg production and disease: adenovirus. PMID- 4312040 TI - Comparison of two canine adenoviruses. PMID- 4312041 TI - Behaviour of some enzymes of the cell envelope of baker's yeast during the digestion of the cell wall. PMID- 4312042 TI - Studies on the nuclear 4 to 7 s RNA of the Novikoff hepatoma. PMID- 4312043 TI - Absolute barrier isolation and antibiotics in the treatment of experimental burn wound sepsis. PMID- 4312044 TI - The combined otolaryngology-neurosurgery approach to extensive benign tumors. PMID- 4312045 TI - Influence of contralateral noise stimulation on tone decay and SISI tests. PMID- 4312047 TI - [A case of small intestine carcinoma]. PMID- 4312046 TI - [What I know from experience about langerhansian adenoma]. PMID- 4312048 TI - [Viral hepatitis]. PMID- 4312049 TI - [Description of a case of hypophosphatasia]. PMID- 4312050 TI - [Changes induced by betamethasone on the intradermic response to angiotensin in children]. PMID- 4312051 TI - [Primitive forms of neurosychological attitude]. PMID- 4312053 TI - [The clinical picture of spinal angiomatosis]. PMID- 4312052 TI - [The so-called paralysis curve of the goldsol reaction in nonsyphiliic neuropathies]. PMID- 4312054 TI - [Classification of neuromuscular diseases]. PMID- 4312055 TI - [Poland syndrome as part of Marfan's disease]. PMID- 4312056 TI - [Contribution of the radiologic study to the diagnosis of primary carcinoma of the gallbladder]. PMID- 4312057 TI - [Treatment of kidney tumors in childhood]. PMID- 4312058 TI - Body distribution of intralymphatically injected radioactive colloid and oil. PMID- 4312059 TI - Rubella-like bone changes in congenital cytomegalic inclusion disease. PMID- 4312060 TI - The spectrum of angiographic findings in hepatoma. PMID- 4312061 TI - [The action of the Rous virus in vitro]. PMID- 4312062 TI - Tubular effect of angiotensin II on the toad kidney. PMID- 4312063 TI - The action of chlorpromazine on the neuromuscular junction. PMID- 4312064 TI - Infections in 18,000 infants and children in a controlled study of respiratory tract disease. I. Adenovirus pathogenicity in relation to serologic type and illness syndrome. PMID- 4312065 TI - Immunologic response to cytomegalovirus infection in renal allograft recipients. PMID- 4312066 TI - Comparison of protective effect of neutralizing antibody in serum and nasal secretions in experimental rhinovirus type 13 illness. PMID- 4312067 TI - Metastatic mucinous adenocarcinoma of the eye. PMID- 4312068 TI - An improved procedure for preparation of inner membrane vesicles from rat liver mitochondria by treatment with digitonin. PMID- 4312069 TI - Studies on the nucleotide specificity of mitochondrial inner membrane particles. PMID- 4312071 TI - Ultrastructural and conformational changes in gas vacuole membranes isolated from Microcystis aeruginosa. PMID- 4312070 TI - Structural analyses of rat liver phosphoglycerides. PMID- 4312072 TI - Glycine metabolism by rat liver mitochondria. IV. Isolation and characterization of hydrogen carrier protein, an essential factor for glycine metabolism. PMID- 4312073 TI - The hydrolysis of estrone sulfate by rat kidney microsomal sulfatase. PMID- 4312074 TI - Terpene biosynthesis: utilization of neryl pyrophosphate by an enzyme system from Pinus radiata seedlings. PMID- 4312075 TI - Spectroscopy and structure of hemerythrin. PMID- 4312076 TI - UDPacetylglucosamine dehydrogenase from Achromobacter georgiopolitanum. PMID- 4312077 TI - [Experimental ovariectomy followed by unsuccessful formation of decidua and infiltrating proliferation of trophoblast; interpretation of analogous human findings during neoplastic distruction of ovarin parenchyma]. PMID- 4312078 TI - [Solitary and multiple glomus tumors]. PMID- 4312080 TI - [Potentiation of supersegmentary synaptic influences on alpha-motoneurons]. PMID- 4312079 TI - [Actual occurrence of swine influenza in Western Slovakia during 1967]. PMID- 4312081 TI - [Ontogenetic development of the respiratory and cardiovascular systems in rats under conditions of training (mechanism of vagal tonus initiation)]. PMID- 4312082 TI - Postabortal anuria due to clostridial infection. PMID- 4312083 TI - The importance of the renin angiotensin system in hypertension due to coarctation of the aorta. PMID- 4312084 TI - [Histochemical study of a variety of pulmonary alveolar cells: cells containing complex lipid inclusions]. PMID- 4312085 TI - [Influence of different aldehydes on preservation of the structure of cultivated cells and the demonstrability of 4 phosphatases]. PMID- 4312086 TI - [Influence of the pH value on localization of 4 phosphatases in cultured chick heart myoblasts]. PMID- 4312087 TI - Morphochemical analysis of mucous cells in the skin and slime glands of hagfishes. PMID- 4312088 TI - A note on the use of p-fluorophenylhydrazine for the cytochemical demonstration of periodate-reactive mucosaccharides and polysaccharides in the electron microscope. PMID- 4312090 TI - Histochemical studies on the enzymes of glycogen metabolism in hamster epididymis. PMID- 4312089 TI - Localization of acetylcholinesterase in the rat myoneural junction. PMID- 4312091 TI - [Experience with a new amebicide, ethychlordiphene]. PMID- 4312092 TI - [Current perspectives in the control of bronchial asthma. Synacthen Depot]. PMID- 4312093 TI - [On allergy to sex hormones. Diagnostic considerations and therapeutic possibilities]. PMID- 4312094 TI - [Fructose-l,6-diphosphatase in the human placenta]. PMID- 4312095 TI - [Initial observations on the ossification time of the sesamoid of the little finger (ouxologic and radiographic findings)]. PMID- 4312096 TI - The role of the renin-angiotensin system in the control of aldosterone secretion. PMID- 4312097 TI - The role of the renin-angiotensin system in the control of aldosterone in man. PMID- 4312098 TI - Studies on the loci of action of stimuli to the biogenesis of aldosterone. PMID- 4312099 TI - Cardiovascular reflexes and the control of aldosterone production and sodium excretion. PMID- 4312100 TI - [Effect of depolarizing muscle relaxants in oncologic patients]. PMID- 4312101 TI - [Effect of succinylcholine at fractional intravenous administration in surgical patients]. PMID- 4312102 TI - [Diagnosis of nesidioma]. PMID- 4312103 TI - [Multilocular cyst of the kidney in a male infant: report of a case]. PMID- 4312104 TI - Decreased incidences of resistance to antimicrobial agents among Escherichia coli and Klebsiella-enterobacter. Observations in a university hospital over a 10-year period. PMID- 4312105 TI - Suppressed plasma renin activity in essential hypertension. Roles of plasma volume, blood pressure, and sympathetic nervous system. PMID- 4312106 TI - Isolation of a RNA-dependent RNA polymerase from virus infected myeloblasts. PMID- 4312107 TI - Further cytophysiologic evidence for the dentity of the cells that produce adrenocorticotrophic hormone. PMID- 4312108 TI - Production of steroids by in vitro superfusion of endocrine tissue. 3. Corticosterone output from rat adrenals stimulated by adrenocorticotropin or cyclic 3',5'-adenosine monophosphate and the inhibitory effect of cycloheximide. PMID- 4312109 TI - Parathyroid hormone-sensitive adenyl cyclase in isolated renal tubules. PMID- 4312110 TI - Pituitary-adrenal function in the squirrel monkey. PMID- 4312111 TI - Functional relationship between the pars intermedia and ACTH secretion in the rat. PMID- 4312112 TI - Effect of ACTH on enzymatic defect produced in vivo by a competitive inhibitor of 3-beta-hydroxysteroid dehydrogenase. PMID- 4312113 TI - Effect of selective surgical interruption of the anterior pituitary's blood supply on ACTH release. PMID- 4312114 TI - Clofibrate inhibits lipid synthesis and ACTH-stimulated steroidogenesis by rat adrenal tissue. PMID- 4312115 TI - Specific retention of an inhibitor of 3-beta-hydroxysteroid dehydrogenase in enzyme-containing tissues of the rat. PMID- 4312116 TI - Composite restorative resins. Council on Dental Materials and Devices. PMID- 4312117 TI - Cytology and growth characteristics of human tumour astrocytes transformed by Rous sarcoma virus. PMID- 4312118 TI - [Aldolase- and hexokinase-isoenzymes in hepatoma]. PMID- 4312119 TI - [Control factor of dehydroepiandrosterone secretion of the adrenal gland of newborn infants]. PMID- 4312120 TI - Stimulation of insulin and growth hormone secretion by adenine nucleotides in primates. PMID- 4312121 TI - Hypophosphatasia. Histopathology of human temporal bones. PMID- 4312122 TI - Synovial sarcoma of the hand. PMID- 4312123 TI - Replicating molecules of polyoma virus DNA. PMID- 4312124 TI - End-vessel reactivity and capillary clearance in diabetes mellitus. PMID- 4312125 TI - Explant culture of rat liver. I. Method, morphology, and cytogenesis. PMID- 4312126 TI - Viral synthesis after simultaneous infection with guanidine-sensitive and guanidine-dependent polioviruses. PMID- 4312127 TI - Adenyl cyclase activity in isolated fat cells from cold exposed rats. PMID- 4312129 TI - On being a patient. PMID- 4312128 TI - Activity of various fractions of bradykinin potentiating factor against angiotensin I converting enzyme. PMID- 4312130 TI - Psychiatric nursing: challenge of the future. PMID- 4312132 TI - Oxidative enzymes in milk and their value as indicators of sub-clinical mastitis in the cow. PMID- 4312131 TI - Relevance of sodium transport pool measurements in toad bladder tissue for the elucidation of the mechanism whereby hormones stimulate active sodium transport. PMID- 4312133 TI - [A study on relationship between pathogenicity and urease-production in coagulase negative staphylococci (staphylococcus albus)]. PMID- 4312134 TI - Herpes simplex hepatitis in an adult. A case report with virological and electron microscopical examination at autopsy. PMID- 4312135 TI - The adrenocorticotropic effect of D-serine-1-norleucine-4-valinamide-25-beta-1-25 corticotropin (DW 75). A comparison with genuine ACTH. PMID- 4312136 TI - Functions of the adenohypophysis: special position of thyrotrophic function. PMID- 4312137 TI - [Growth assays of 4 strains of Smallpox virus in RK13 and BHK21 tissue culture]. PMID- 4312138 TI - [Viral particle specific serums, used in complement fixation tests of foot-and mouth disease virus]. PMID- 4312139 TI - [Information supplied by the radio-immunologic determination of the plasma somatotropic hormone during fasting and after administration of insulin, arginine and glucose per os in 14 cases of nanism in child. Demonstration of an isolated somatotropin deficiency in 2 cases]. PMID- 4312140 TI - [Presentation of photographic documents and filus relative to multinucleated trophozoites of Entamoeba histolytica in vitro. Interpretation and discussion]. PMID- 4312142 TI - [Sensitivity to ampicillin of 578 bacterial strains isolated in Africa]. PMID- 4312143 TI - [Prostaglandins]. PMID- 4312141 TI - [Are there 2 pathogenic types of leprous reaction? Therapuetical results]. PMID- 4312144 TI - The effect of angiotensin on isolated rabbit renal tubules. PMID- 4312145 TI - The cardiovascular response to vertebral artery infusions of angiotensin in the dog. PMID- 4312146 TI - Efferent pathways of the cardiovascular response to vertebral artery infusions of angiotensin in the dog. PMID- 4312147 TI - Alterations in carbohydrate metabolism in Jamaican children with severe malnutrition. PMID- 4312148 TI - Response of kidney and salivary gland G-6-PD and renin to adrenalectomy, angiotensin, bradykinin and meralluride. PMID- 4312149 TI - [1-Alkyl-3-bromoacetyl-pyridinium bromides as inhibitors of lactate dehydrogenase from swine heart]. PMID- 4312150 TI - Interrelationship between salvage pathway and synthesis de novo of adenine nucleotides in kidney slices. PMID- 4312151 TI - [Osseous senescence]. PMID- 4312152 TI - [Therapy of thymomegaly. Observations on 100 cases]. PMID- 4312153 TI - [The angiotensin skin test in childhood]. PMID- 4312154 TI - [Bone marrow transplantation after administration of large doses of a radioactive solution of yttrium silicate with Y90 in experimental leukemia]. PMID- 4312155 TI - [Treatment of patients with acute leukemia in the remission stage]. PMID- 4312156 TI - [Lipoma of the esophagus]. PMID- 4312157 TI - [Infiltrating form of cancer of the lower 3d part of the esophagus]. PMID- 4312158 TI - [Cancer on a scar of caustic stenosis of the esophagus dating from childhood]. PMID- 4312160 TI - [Calcified cancer of the stomach]. PMID- 4312159 TI - [Prepyloric ulcerative cancer. Practical value of fibrous gastroscopy]. PMID- 4312161 TI - [An unusual form of gastric lymphosarcoma with multiple ulcerations]. PMID- 4312162 TI - [Benign tumor of the pyloric antrum prolapsed into the duodenum. Associated duodenal ulcer]. PMID- 4312163 TI - [Lymphoid tumor of the stomach]. PMID- 4312164 TI - [Gastric schwannoma]. PMID- 4312165 TI - [Nontumurous ileal stenosis]. PMID- 4312166 TI - [Recurring stenosis of the jejunum]. PMID- 4312167 TI - [Upper jejunal stenosis: Crohn's disease?]. PMID- 4312168 TI - [2 cases of large benign schwannoma of the mesentery]. PMID- 4312170 TI - [Stenosis of an old latero-lateral ileo-ileal anastomosis]. PMID- 4312169 TI - [Ileo-intracolic intussusception of Meckel's diverticulum]. PMID- 4312172 TI - [Dissecting abscess of the wall of the sigmoid]. PMID- 4312171 TI - [Carcinoid tumor and foreign body of the small intestine. Diagnosis in 3 stages]. PMID- 4312173 TI - [Foreign body in the sigmoid colon]. PMID- 4312174 TI - [Giant megasigmoid]. PMID- 4312175 TI - [Difficulties in interpretation of some aspects of peroperative cholangiography]. PMID- 4312176 TI - [Massive digestive hemorrhage due to erosion of the gastroduodenal artery into a pseudocyst of the pancreas]. PMID- 4312177 TI - [Place of the selective arteriography in the islet cell tumor. 2 cases]. PMID- 4312178 TI - [Diaphragmatic hernia through Larrey's fissure]. PMID- 4312179 TI - [Peculiarities of morphological changes in peripheral nervous system in experimental allergic polyneuritis]. PMID- 4312180 TI - [On the functional state of the pituitary-adrenal system in multiple sclerosis and acute disseminated encephalomyelitis]. PMID- 4312181 TI - [Neurohumoral regulation of the lability of myoneural synapses in schizophrenic patients]. PMID- 4312182 TI - Blood circulation in the intestine of the cat under halothane anaesthesia. PMID- 4312183 TI - [Submicroscopic and enzyme histochemical changes in rat pineal body during puberty]. PMID- 4312184 TI - [An antimycin A and alkane sensitive, soluble NADH2 dehydrogenase from rat liver. II. Kinetic studies of the effect of substrate and acceptor on the enzyme activity]. PMID- 4312185 TI - [Thin layer chromatographic isolation of aldosterone from the urine of pregnant women using polyamide and silica gel layers]. PMID- 4312186 TI - [The use of a fluorometric method for the determination of unconjugated 11 hydroxycorticosteroids with a "Spekol" measuring device]. PMID- 4312188 TI - [An antigen community between ascites tumor cells of mouse and rat on the one hand and dog erythrocytes on the other]. PMID- 4312187 TI - [An antimycin A-sensitive, soluble NADH2 dehydrogenase from the rat liver. 3. Kinetic studies of the effect of inhibitors]. PMID- 4312189 TI - [The Reissner's fiber as a receptor model for biogenous amines. I. Binding of noradrenaline and adrenaline]. PMID- 4312190 TI - Enzyme histochemistry of the bovine ovaries in normal and cystic conditions. PMID- 4312191 TI - [Enzyme histochemistry of salivary gland tumors]. PMID- 4312192 TI - Electron microscopic studies concerning the structural mechanism of the development of mental disturbance in experimental chronic methamphetamine poisoning. PMID- 4312193 TI - [The incorporation of IDU into viral DNA of herpes simplex virus]. PMID- 4312194 TI - Acute parotitis associated with parainfluenza 3 virus infection. PMID- 4312195 TI - Manifest dream content in normal and psychopathologic states. PMID- 4312196 TI - [Localization of fibrin in human tumors]. PMID- 4312197 TI - [Characteristics of glycogen levels in tumors of mesodermal origin]. PMID- 4312198 TI - [Possibility of using Coons' method for detecting a myogenic component of Wilms' tumor]. PMID- 4312199 TI - Studies on the mechanism of inhibitionof the mitochondrial electron transport by antimycin. II. Antimycin as an allosteric inhibitor. PMID- 4312200 TI - The localization of plmitoyl-CoA: carnitine palmitoyl-transferase in rat liver. PMID- 4312201 TI - Inhibition of photosynthesis in isolated spinach chloroplasts by added fructose 1,6-diphosphatase. PMID- 4312202 TI - The subcellular localization of alcohol dehydrogenase activity in baker's yeast. PMID- 4312203 TI - Succinate dehydrogenase. II. The effect of phospholipases on particulate and soluble succinate dehydrogenase. PMID- 4312204 TI - An extractable collagenase from crustacean hepatopancreas. PMID- 4312205 TI - Phosphotransacetylase of Escherichia coli B, activation by pyruvate and inhibition by NADH and certain nucleotides. PMID- 4312206 TI - The zinc requirement of dinucleotide pyrophosphatase in mammalian organs. PMID- 4312207 TI - Purification and properties of a ribonuclease from Avena leaf tissues. PMID- 4312208 TI - Effects of cetyltrimethylammonium bromide on catalytic properties of kidney microsomal glucose-6-phosphatase, inorganic pyrophosphate-glucose phosphotransferase and inorganic pyrophosphatase activities. PMID- 4312210 TI - Detection of guanyl cyclase in mammalian tissues. PMID- 4312209 TI - Purification and properties of endopeptidase from rabbit red cells and its process of degradation of angiotensin. PMID- 4312211 TI - Relationship of L-alanine and L-glutamate dehydrogenases of Bacillus thuringienses. PMID- 4312212 TI - NAD-specific isocitrate dehydrogenase from a plant source. Sigmoid kinetics and enzyme stability. PMID- 4312213 TI - Inhibition of adenine phosphoriboxyltransferase by pyrophosphate. PMID- 4312214 TI - Acid and alkaline ribonucleases of plasma. PMID- 4312215 TI - Electron paramagnetic resonance spectra of amine oxidase from Aspergillus niger. PMID- 4312216 TI - (Mg2+ Na+ K+)-ATPase activity of liver from tumor bearing rats. PMID- 4312217 TI - Observations on the reflex response to muscle vibration in man and its voluntary control. PMID- 4312218 TI - [Enzymatic depletion and chick embryo cartilage regeneration cultured in vitro]. PMID- 4312219 TI - [Kinetics of the development of Rous sarcoma virus (Schmidt-Ruppin strain). Estimation of RNA synthesis time. Electron microscope autoradiography study]. PMID- 4312220 TI - [Depletion of chick embryo vertebral cartilage by a mixture of enzymes and its regeneration in culture in vitro]. PMID- 4312221 TI - [Preparation and study of some biological properties of 3',5'-adenosine phosphoric acid analogs]. PMID- 4312222 TI - [Effect of ethanol on the relationship NAD+ NADH in rat stomach mucosa]. PMID- 4312223 TI - [Organization and differentiation of mature mouse mammary tumor virus particles]. PMID- 4312224 TI - [Development kinetics of Rous sarcoma virus (Schmidt-Ruppin strain). Estimation of arginine incorporation time into viral proteins. Electron microscope autoradiographic study]. PMID- 4312225 TI - The production of alpha-hydroxyglutaric acid from glutamic acid by cell-free preparations of Peptococcus aerogenes. PMID- 4312226 TI - Lactic dehydrogenase isozyme distributions in various cell types of the mammalian liver. PMID- 4312228 TI - [Chemical neurotransmission in the central nervous system]. PMID- 4312227 TI - Fractionation of DNA on columns of poly-L-lysine supported on kieselguhr. PMID- 4312230 TI - Adenoviral pneumonia and its complications in infancy and childhood. PMID- 4312229 TI - Cation transport. I. Metabolic activity of the polyphosphoinositide complex in isolated renal cortex tubules. PMID- 4312231 TI - Unilateral hyperlucent lung: a complication of viral pneumonia. PMID- 4312232 TI - Iodoventriculography in hydromyelia. PMID- 4312233 TI - Renal arteriography in the pediatric age group. PMID- 4312235 TI - Current treatment of Wilms tumor. PMID- 4312234 TI - The autonomic innervation of human submandibular and parotid glands. PMID- 4312237 TI - Hepatocancerogenesis in mice with the simutaneous administration of diethylnitrosamine and the virus Motol. PMID- 4312236 TI - [Criteria for identification of Clostridium perfringens. 5. Capsule formation and urease production]. PMID- 4312238 TI - Erythroblastosis and erythroblastic leukemia in rats induced by material from chick erythroblastosis. PMID- 4312239 TI - Investigations on the transformation of fibroadenoma of the breast into malignant cystosarcoma phyllodes. PMID- 4312240 TI - The acute effects of reserpine on the sleep-wakefulness cycle in rabbits. PMID- 4312241 TI - [Ontogenesis of sleep and waking states in mammals]. PMID- 4312242 TI - [Treatment of bronchial asthma using a synthetic beta 1-18 corticotropin derivative]. PMID- 4312243 TI - [Effect of several sugars and coenzymes on ethanol disappearance speed in rabbit blood]. PMID- 4312245 TI - [Theophylline and insulin secretion]. PMID- 4312244 TI - [Hyperglycemia provoked in vivo in rats and rabbits by xanthine base-cyclic AMP combinations]. PMID- 4312246 TI - [Beta-glucuronidase activity of the cerebrospinal fluid of patients with brain tumors]. PMID- 4312247 TI - The role of the hospital laboratory in the diagnosis of viral diseases. I. Basic concepts. PMID- 4312248 TI - Adverse cutaneous reaction to oral contraceptives. PMID- 4312249 TI - Intestinal parasites. PMID- 4312251 TI - Primary liver-cell carcinoma in a young thoroughbred horse. PMID- 4312250 TI - Reversible dissociation of tetrameric rabbit muscle glyceraldehyde 3-phosphate dehydrogenase into dimers or monomers by adenosine triphosphate. PMID- 4312252 TI - A review of the literature: collagen: its physical characteristics and degradation. PMID- 4312253 TI - [Functions in ambulatory care and rehabilitation of patients in a district]. PMID- 4312254 TI - The nurse migrates. PMID- 4312255 TI - Utilization--a vehicle for the effective delivery of patient care services. PMID- 4312256 TI - [Inactivation by rat kidney homogenates of angiotensin following unilateral renal ischemia, adrenalectomy and pretreatment with DOC and sodium chloride]. PMID- 4312257 TI - Fair and pleasing medicines. PMID- 4312259 TI - [I wonder if my public health nurse knows that I have been in the hospital]. PMID- 4312260 TI - [The sluice gate institute. Procedures applied at discharge]. PMID- 4312258 TI - [Improved communication]. PMID- 4312261 TI - [Interaction between tumor viruses and cells]. PMID- 4312262 TI - [Histotopochemistry and histopathochemistry of peripheral nervous system in the case of injuries and tumors]. PMID- 4312263 TI - A case of homologous liver transplantation. PMID- 4312264 TI - The differential diagnosis of benign cholangioma and liver metastases. PMID- 4312265 TI - Effects of thyrotropin, sodium fluoride and ions on thyroid slice metabolism. PMID- 4312266 TI - Studies on phenolic steroids in human subjects. 13. A rapid assay of urinary estrogen conjugates in pregnancy. PMID- 4312267 TI - [Orthodontics in Copenhagen]. PMID- 4312268 TI - Wilms' tumor: the evolution of a treatment program. PMID- 4312269 TI - Electron paramagnetic resonance study of free radical products of the reaction of ninhydrin with amino acids, peptides and proteins. PMID- 4312270 TI - Circular dichroism of proteins of known and unknown conformations. PMID- 4312271 TI - [Malignant tumours in childhood. Results of a cooperative therapeutic study using cyclophosphamide anal x-rays]. PMID- 4312272 TI - [The effect of ACTH on the endocrine organs of castrated rats]. PMID- 4312273 TI - Pyrophosphate enhancement of thyrocalcitonin effect in tissue culture. PMID- 4312274 TI - [Functional study on the control of dynamic and static fusimotor fiber activity by the mesencephalic, pontine and bulbar reticular formations in the cat]. PMID- 4312275 TI - [Studies on the light-induced cytochrome oxidation in the photosynthetizing purple bacteria Rhodopseudomonas sp]. PMID- 4312276 TI - Modification of the indirect haemagglutination test for amoebiasis. AB - Optimal conditions for carrying out the indirect haemagglutination test with sheep erythrocytes were studied using the microtitre system. The age of the erythrocytes, concentration of reagents, time and temperature of tanning, sensitization, and incubation are described with reference to replication of titres. Sera from patients with amoebic colitis were used to evaluate the test conditions. PMID- 4312277 TI - Chemodectoma of the orbit. AB - The histological and clinical features of a primary chemodectoma arising in the orbit are described. It is suggested that the tumour may have arisen from chemoreceptor tissue in the area of the lacrimal gland. PMID- 4312278 TI - Plasma "cortisol" levels in right and left ventricular failure. AB - Plasma ;cortisol' values are reported in 36 patients during or following right ventricular failure, and 12 during or following left ventricular failure. In patients with right ventricular failure the normal circadian rhythm was abolished with elevation of midnight values. Disturbance of rhythm was less marked in left ventricular failure, although midnight values were usually raised. Dexamethasone suppression of plasma ;cortisol' levels was abolished or reduced in right ventricular failure. These results confirm our earlier findings and further support our contention that the disturbance of circadian rhythm is not due to a simple stress mechanism. The results are of importance in the differential diagnosis of Cushing's syndrome based on plasma ;cortisol' values, if there is concomitant right ventricular failure. PMID- 4312280 TI - Studies on the susceptibility of organ cultures to infection and on the localization of the virus in the cultures. PMID- 4312279 TI - Binding of antibiotics to tissue homogenates. PMID- 4312281 TI - [Role of several viruses in the etiology of pneumonia in children]. PMID- 4312282 TI - [Diagnostic method and its clinical usefulness in hypothalamo-hypophyseo-adrenal insufficiency in children]. PMID- 4312284 TI - [Antibiotic therapy in infancy]. PMID- 4312286 TI - [Renin, angiotensin, aldosterone and arterial hypertension. I]. PMID- 4312283 TI - [Cytochemical examinations in the differentiation of acute leukemias]. PMID- 4312285 TI - Electrical properties and synaptic connections of the sympathetic neurons in the rat and guinea-pig superior cervical ganglion. PMID- 4312287 TI - [Secondary amenorrhea, the first symptom of hepatoma]. PMID- 4312289 TI - [The problem of ischemic vascular peripheral neuropathy]. PMID- 4312288 TI - [The tarsal tunnel syndrome. Clinical picture and results of operative surgery based on 39 own observations]. PMID- 4312290 TI - Cortical unit activity in desynchronized sleep. AB - Bursts of unit firing associated with surface positive electroencephalogram waves and rapid eye movements account for the mean increase in discharge rate in desynchronized sleep over that of the synchronized phase. Firing rate begins to change toward the value it will assume in desynchronized sleep in the minute before the usual electrographic criteria of desynchronized sleep are present. PMID- 4312292 TI - Biochemical changes in the interscapular brown adipose tissue of rats during the cold acclimation process. Effect of ionizing radiation on growth of brown fat. ANL-7409. PMID- 4312294 TI - Induction of ultrastructural lesions in rat adrenal cortex by 3-acetylpyridine. ANL-7409. PMID- 4312291 TI - [Hormonal activity of the adrenal cortex in patients with atherosclerotic cardiosclerosis with chronic circulatory insufficiency]. PMID- 4312293 TI - The distribution of mitochondrial enzymes in rat liver after various treatments, in liver from other species, and in rat heart. ANL-7409. PMID- 4312295 TI - [Depression of inhibitory postsynaptic components of responses to flashes of light during application of an auditory stimulus]. PMID- 4312296 TI - [Histochemical studies of some enzyme changes during aging of sausages]. PMID- 4312297 TI - [Determination of rhodopsin and its resynthesis in homogenates of retina]. PMID- 4312298 TI - [Tumor lipids. The phospholipid composition of Zajdela ascites rat hepatoma plasma membranes]. PMID- 4312299 TI - [On the mechanism of action of yeast inorganic pyrophosphatase]. PMID- 4312300 TI - [Isolation and characteristics of deoxydribonuclease from Bac. mesentericus]. PMID- 4312301 TI - [Phosphorylation of histones from liver and hepatoma ascites cells]. PMID- 4312302 TI - [Investigation of amino acid synthesis in normal tissues and tumors of man and animals]. PMID- 4312304 TI - Cardiovascular responses of the cat to mesenteric intra-arterial administration of nicotine, cyanide and venous blood. PMID- 4312303 TI - [Determination of molecular weight of the enzyme and non-enzyme proteins of bacterial membranes employing radiation inactivation and disk-electrophoresis]. PMID- 4312305 TI - Serum electrolyte abnormalities associated with the administration of polymyxin B in febrile leukemic patients. PMID- 4312306 TI - [Central mechanisms determining the character of catecholamine effect on sympathetic tonus and vasomotor reflex]. PMID- 4312307 TI - [Antineoplastic activity and toxicity of dipin during some effect on the thymus gland]. PMID- 4312308 TI - [Effect of ACTH and cortisone on the behavior of some enzymes in the epithelium and glands of the jejunum and colon in the white rats]. PMID- 4312310 TI - [Latent viruses in the salivary glands]. PMID- 4312309 TI - [Histochemical studies on the embryogenesis of cross-striated muscles in guinea pigs in the 1st half of pregnancy]. PMID- 4312311 TI - Saphenous nerve conduction in man. PMID- 4312312 TI - Methods of tendon jerk reinforcement. The role of muscle activity in reflex excitability. PMID- 4312313 TI - The effect of local pressure in diphtheritic neuropathy. PMID- 4312314 TI - Compartmental redistribution of 99mTc-pertechnetate in the presence of perchlorate ion and its relation to plasma protein binding. PMID- 4312315 TI - [Malignant mixed tumor of the thumb]. PMID- 4312316 TI - [Dissecting mole (chorioadenoma destruens)]. PMID- 4312317 TI - [Synoviosarcoma of the elbow]. PMID- 4312318 TI - Carbon monoxide intoxication with peripheral neuropathy. PMID- 4312319 TI - Increase of cytochromes a and a3 in rat kidney mitochondria in response to administration of aldosterone in vivo. PMID- 4312320 TI - [The etiology of sporadic respiratory infections in young children]. PMID- 4312321 TI - [Evolution of the diagnosis of influenza]. PMID- 4312322 TI - [The role of alunite in the formation of focal shadows in the lungs]. PMID- 4312323 TI - [Complications in bronchography]. PMID- 4312328 TI - [Bilateral renal dysplasia in an infant]. PMID- 4312330 TI - [Chronic peripheral nerve diseases of uncertain origin]. PMID- 4312329 TI - [A fluorimetric assay for unconjugated 11-beta-hydroxy-corticosteroids in small serum samples (0.1--0.3ml) and their value in pediatric endocrine diagnosis]. PMID- 4312331 TI - [Associated monolateral lesion of the motor trigeminal and facial nerve]. PMID- 4312332 TI - Heart tone. PMID- 4312333 TI - Congenital and neonatal anomalies linked with viral infections in experimental animals. PMID- 4312334 TI - Endobronchial granular cell myoblastoma. A report of three cases and review of the literature. PMID- 4312335 TI - A histochemical and electron microscopic study of Gaucher cells. PMID- 4312336 TI - The pancreatic beta cell. Demonstration with peroxidase-labeled antibody technique. PMID- 4312337 TI - [Histochemical study of several enzymes in the vascular wall in rabbits with renal hypertension]. PMID- 4312340 TI - The effect of ethyl alcohol on inferred visual dreaming. PMID- 4312339 TI - Histochemical comparison of the effects of a carcinogenic and a non-carcinogenic derivative of tricycloquinazoline. PMID- 4312341 TI - Antidepressant drugs and sleep. PMID- 4312343 TI - A fourth dimension of consciousness. PMID- 4312342 TI - LSD and the sleep-dream cycle. PMID- 4312344 TI - Dreams in narcolepsy, hypersomnia and dissociated sleep disorders. PMID- 4312345 TI - Telepathy and dreams. PMID- 4312346 TI - Peripheral hormonal and metabolic correlates of rapid eye movement sleep. PMID- 4312347 TI - Drugs and dreams, a synthesis. PMID- 4312348 TI - The effects of drugs on the EEG sleep patterns of normal humans. PMID- 4312349 TI - Sleep. PMID- 4312350 TI - Modification of subsequent intracerebral infection with Bordetella pertussis by previous local brain irradiation. PMID- 4312351 TI - Fast and slow mammalian muscles after denervation. PMID- 4312352 TI - [Urinary 17-hydroxycorticosteroid fractions]. PMID- 4312353 TI - [Experimental studies on the mechanism of ACTH secretion]. PMID- 4312354 TI - [Hexokinase and glucokinase in the rat liver. II. Effects of thyroid and pituitary hormones on enzyme activity]. PMID- 4312355 TI - [Diagnostic procedures in exanthematous diseases, with special reference to some viral exanthemas]. PMID- 4312356 TI - [Hormone therapy of muscular atrophy]. PMID- 4312357 TI - [Case of cerebral mass showing a right cerebellar hemispherical syndrome]. PMID- 4312359 TI - Separation of conjugated urinary estrogens on columns of sephadex. II. Sequential separations. PMID- 4312358 TI - Respiration and protein synthesis in Escherichia coli membrane-envelope fragments. II. Effects of fatty acids and albumin on respiration. AB - Fatty acids inhibited the ability of Escherichia coli membrane-envelope fragments to catalyze the oxidation of succinate and nicotinamide adenine dinucleotide, reduced form (NADH) and also inhibited the response of the Clark oxygen electrode to nonenzymatic oxygen uptake. In all cases, unsaturated fatty acids were much more inhibitory than saturated fatty acids. Albumin afforded complete protection from inhibition in the nonenzymatic oxygen-uptake experiments but only partial protection for the respiratory activities of the membrane fragments. The succinoxidase activity was totally inhibited by bovine serum albumin at concentrations that inhibited succinate dehydrogenase only slightly and NADH oxidase not at all. The E. coli acellular preparation showed no dehydrogenase or oxidase activity for any of the fatty acids under a variety of conditions. These conditions included variations of pH, concentration of fatty acids, and the presence or absence of albumin, CoA, ATP, NAD, cysteine, succinate, and carnitine. It thus appears that E. coli grown in the absence of fatty acid can not use fatty acids as an energy source. PMID- 4312360 TI - The structure of viruses of the papilloma-polyoma type. V. Tubular variants built of pentamers. PMID- 4312362 TI - Nuclear fragmentations and associated fibrils in giant cell tumor of bone. PMID- 4312361 TI - Studies on the bacteriophage MS2. VII. Structure determination of the longer polypurine sequences present in the pancreatic ribonuclease digest of the viral RNA. PMID- 4312363 TI - Effect of a DNA tumour virus on antibody forming cells in neonatally infected hamsters. PMID- 4312364 TI - Transformation and virus growth by murine sarcoma viruses in human cells. PMID- 4312365 TI - Prevalence, incidence and persistence of EB virus antibody in young adults. PMID- 4312366 TI - Long-term follow-up of renal functions of 108 children who underwent nephrectomy for malignant disease. PMID- 4312367 TI - The incidence of cytomegalovirus, herpes simplex, rubella, and toxoplasma antibodies in microcephalic, mentally retarded, and normocephalic children. PMID- 4312368 TI - Telepathic perception in the dream state: confirmatory study using EEG-EOG monitoring techniques. PMID- 4312369 TI - [Spinal epidural abscess]. PMID- 4312370 TI - [Hypnosis in chronic sleep disorders]. PMID- 4312371 TI - Carcinogenesis by RNA sarcoma viruses. XII. A quantitative study of infection of rat cells in vitro by avian sarcoma viruses. PMID- 4312372 TI - The step in cellular DNA synthesis blocked by Newcastle disease or mengovirus infection. PMID- 4312373 TI - Induction of virus synthesis in polyoma transformed cells by ultraviolet light and mitomycin C. PMID- 4312375 TI - A type of chick embryo cell that fails to support formation of infectious RSV. PMID- 4312374 TI - Ethylene production by detached leaves infected with tobacco mosaic virus. PMID- 4312376 TI - [Food ingestion and the way it effects motoricity of the large intestine]. PMID- 4312377 TI - [Toxico-hygienic characteristics of oxymethylfurfural]. PMID- 4312378 TI - [Glomus tumor of the plantar aspect of the foot]. PMID- 4312379 TI - Ampicillin sensitivity in infectious mononucleosis. PMID- 4312380 TI - The effect of adrenergic drugs on the isolated tracheal tube in vitro and on the bronchial resistance to inflation in vivo. PMID- 4312382 TI - [Injuries of the cutaneous nerves on the forearm]. PMID- 4312381 TI - [Influence of local anesthetics on the excitation activity of bradykinin on smooth muscle. II. Potentiation of bradykinin contraction in the guinea pig ileum]. PMID- 4312383 TI - [Diagnostic value of the combination of gammaencephalography, electroencephalography, echo-encephalography, arteriography, and pneumoencephalography in brain tumors]. PMID- 4312384 TI - [Diagnosis and therapy of cerebral hemorrhage in children]. PMID- 4312385 TI - [The value of local diagnosis in Gerstmann's Syndrome]. PMID- 4312387 TI - [The clinical picture of glioblastoma multiforme in patients of younger age groups]. PMID- 4312386 TI - [Rapid clinical diagnosis of brain tumors]. PMID- 4312388 TI - Isolation and characterization of terminal polynucleotide fragments from bacteriophage ribonucleic acids. PMID- 4312389 TI - Mechanistic studies on equine liver alcohol dehydrogenase. I. The stoichiometry relationship of the coenzyme binding sites to the catalytic sites active in the reduction of aromatic aldehydes in the transient state. PMID- 4312390 TI - Phospholipid class and fatty acid composition of golgi apparatus isolated from rat liver and comparison with other cell fractions. PMID- 4312391 TI - The composition and structure of carbohydrate moiety of stem bromelain. PMID- 4312392 TI - Biosynthesis of cyclic diterpenes in extracts from seedlings of Ricinus communis L. II. Conversion of geranylgeranyl pyrophosphate into diterpene hydrocarbons and partial purification of the cyclization enzymes. PMID- 4312393 TI - [Current aspects of infectious diseases. 2]. PMID- 4312394 TI - [Plasma renin activity in pheochromocytoma]. PMID- 4312395 TI - Are beta-receptors involved in the uptake by cardiac sympathetic nerves of infused and released noradrenaline? PMID- 4312396 TI - Nonspecific denervation supersensitivity in the rat vas deferens "in vitro". PMID- 4312397 TI - [Hygienic characteristics of fluxed agglomerate dust]. PMID- 4312398 TI - [The silicon content of internal organs of miners and sandblasters in silicotuberculosis]. PMID- 4312400 TI - [Pulmonary histiocyto-fibroxanthoma with vascular malformation]. PMID- 4312401 TI - Relationship between nucleolus and nuclear bodies in human mixed salivary tumors. PMID- 4312399 TI - Gram-negative bacilli in burns. AB - In a period of two years, 865 strains of Gram-negative bacilli other than Pseudomonas aeruginosa isolated from burns were identified by a range of tests. The commonest species were Proteus mirabilis, Escherichia coli, and Enterobacter cloacae. Many strains of Klebsiella aerogenes, Enterobacter aerogenes, and Bacterium anitratum were also found.A large proportion of the strains were tested for sensitivity to nalidixic acid, ampicillin, kanamycin, chloramphenicol, tetracycline, and carbenicillin, and smaller numbers of strains were tested for sensitivity to cephaloridine, polymyxin, streptomycin, sulphadiazine, sulfamylon, and trimethoprim. The proportion of strains sensitive and resistant to different antibacterial agents varied widely with species of bacteria. A large proportion of the strains of E. coli and P. mirabilis were resistant to ampicillin, which was much used in treatment; resistance appeared least often towards nalidixic acid, kanamycin, trimethoprim, and gentamicin. Multiple resistance occurred less often among strains of E. coli than among Klebsiella spp, Enterobacter spp, and P. mirabilis. Phage and serological typing of Ps. aeruginosa showed that most infections of burns with this organism were due to strains previously found in other patients in the same ward. Taken with other evidence, this supported the view that most infections with Ps. aeruginosa were not acquired from the patient's own flora but from sources in the hospital environment. PMID- 4312402 TI - Evolution of steroids and their value in the control of rheumatic disease. PMID- 4312403 TI - Malignant hepatoma: evaluation of surgical (including needle biopsy) material from 69 cases. PMID- 4312404 TI - Chemotherapeutic agents in childhood malignancies. PMID- 4312405 TI - Chromosomes and abortions. PMID- 4312406 TI - Study on the action of olivine on macrophages "in vitro". PMID- 4312407 TI - [Acute or subacute cardiomyopathy observed in Abidjan. Etiologic approach apropos of 26 cases]. PMID- 4312408 TI - [Characteristics of psychophysiological activity during sleep: a contribution to evaluation technics]. PMID- 4312409 TI - Neurologic surgery. PMID- 4312410 TI - Amniocentesis: a new approach to some old problems in obstetrics. PMID- 4312411 TI - [Culture medium dependency of nuclease biosynthesis in proteus strains]. PMID- 4312412 TI - [Contribution to the so-called postperfusion syndrome]. PMID- 4312413 TI - [Pendred's syndrome]. PMID- 4312414 TI - [Reliability of the determination of 17-ketosteroids by gas chromatography and correlation with the values obtained by the Zimmermann method]. PMID- 4312415 TI - [Biochemical and histochemical studies of fructosephosphate aldolase in tumors of the nervous system. Isoenzymes of fructosephosphate aldolase. 8]. PMID- 4312416 TI - Effect of phenobarbital on rat liver acyl-phosphohydrolases. PMID- 4312417 TI - Electroencephalographic study of diazepam on patients with diagnosis of episodic behavioral disorders. PMID- 4312418 TI - Effect of silica gel on stability and biological availability of ascorbic acid. PMID- 4312419 TI - [A case of glomus jugulare tumor]. PMID- 4312421 TI - [Effects of an association of oxytocin and ACTH on the clinical and electroencephalographic manifestations of edematogenic cerebral lesions]. PMID- 4312420 TI - [Cerebral edema. Therapeutic considerations]. PMID- 4312422 TI - [Erotic changes in epilepsy and brain tumors]. PMID- 4312423 TI - Specificity of the renin-like enzyme of rabbit uterus. PMID- 4312424 TI - The enzymic composition of the isolated cell wall and plasma membrane of baker's yeast. AB - A study was made of the enzyme content of the isolated cell walls and of a plasma membrane preparation obtained by centrifugation after enzymic digestion of the cell walls of baker's yeast. The isolated cell walls showed no hexokinase, alkaline phosphatase, esterase or NADH oxidase activity. It was concluded that these enzymes exist only in the interior of the cell. Further, only a negligible activity of deamidase was detectable in the cell walls. Noticeable amounts of saccharase, phosphatases hydrolysing p-nitrophenyl phosphate, ATP, ADP, thiamin pyrophosphate and PP(i), with optimum activity at pH3-4, and an activity of Mg(2+)-dependent adenosine triphosphatase at neutral pH, were found in the isolated cell walls. During enzymic digestion, the other activities appearing in the cell walls were mostly released into the medium, but the bulk of the Mg(2+) dependent adenosine triphosphatase remained in the plasma-membrane preparation. Accordingly, it may be assumed that the enzymes released into the medium during digestion are located in the cell wall outside the plasma membrane, whereas the Mg(2+)-dependent adenosine triphosphatase is an enzyme of the plasma membrane. This enzyme differs from the phosphatases with pH optima in the range pH3-4 with regard to location, pH optimum, substrate specificity and different requirement of activators. PMID- 4312425 TI - [Respiratory system in cerebral edema]. PMID- 4312426 TI - A comparison of the effects of suxamethonium and tubocurarine in patients in London and New York. PMID- 4312428 TI - Trigeminal sensory neuropathy. PMID- 4312427 TI - Virus in genital warts. PMID- 4312429 TI - [Sensitization by metabolic inhibitors of isolated rat intestine to the effects of sympathomimetics. The case of adrenaline]. PMID- 4312431 TI - [Antigen specificity of a group of avian oncogenic viruses in clones of hamster cells transformed by Rous virus]. PMID- 4312430 TI - [Carcinogenic action of sodium cyclymates in mice]. PMID- 4312433 TI - [New chemical substances with therapeutic effect: synthetic ACTH]. PMID- 4312432 TI - The influence of the pituitary gland on sodium conservation, and plasma renin and renin substrate concentrations in the rat. PMID- 4312434 TI - Study of the reciprocal relationship of the exoantigens of Clostridium perfringens type A in the culture medium and the bacterial cells during cultivation. PMID- 4312435 TI - [The hyperbaraic oxygen therapy in gas gangrene infections in gynecology]. PMID- 4312436 TI - [Significance of vasoconstriction with angiotensin II for the evacuation of blood glucose to the tissues]. PMID- 4312438 TI - Immune response of rabbits to purified papovavirus SV40. PMID- 4312439 TI - Intracellular recordings from cat cochlear nucleus during tone stimulation. PMID- 4312440 TI - Excitability changes and inhibitory mechanisms in neocortical neurons during seizures. PMID- 4312437 TI - Further purification of the glycoprotein that induces nephrotoxic antibody: isolation of the active polysaccharide fraction mainly composed of glucose. PMID- 4312441 TI - Organization of flight motoneurons of diptera. PMID- 4312442 TI - Differential effects of septal and olfactory volleys on intracellular responses of hippocampal neurons in awake, sitting monkeys. PMID- 4312443 TI - [Ventriculography using an emulsion of "Lipiodol F"]. PMID- 4312444 TI - [Paralysis of the brachial plexus in breast cancer]. PMID- 4312446 TI - [Hornsyld Hospital as a convalescent department. 3-year assessment of the surgical section]. PMID- 4312445 TI - [Broncho-pulmonary cancer with true or degraded hypercorticism]. PMID- 4312447 TI - [Chronic idiopathic hypokalemia with hyperkaliuria in a very young infant. (Bioclinical and histological study)]. PMID- 4312448 TI - Pathogenesis of ulcers of the alkali-burned cornea. PMID- 4312449 TI - Human pituitary growth hormone. Studies of the tryptophan residue. PMID- 4312450 TI - An investigation of the products of an enzymic hydrolysis of collagens. PMID- 4312451 TI - The glutamyl linkages in collagen. PMID- 4312452 TI - Free energy of subunit interactions. Hemerythrin. PMID- 4312453 TI - Electron paramagnetic resonance of nitric oxide--protoheme complexes with some nitrogenous base. Model systems of nitric oxide hemoproteins. PMID- 4312454 TI - Requirement of different sulfhydryl groups in the activation and transfer reactions of isoleucyl transfer ribonucleic acid synthetase. PMID- 4312456 TI - Comparison of metal-binding properties of trans-1,2-cyclohexanediol diphosphate and deacylated phosphoinositides. PMID- 4312455 TI - Permeation as the rate-limiting step in the phosphorylation of uridine and choline and their incorporation into macromolecules by Novikoff hepatoma cells. Competitive inhibition by phenethyl alcohol, persantin, and adenosine. PMID- 4312457 TI - Use of venom exonuclease at low pH for preparation of mononucleoside diphosphates. PMID- 4312458 TI - Chloroquine and synthesis of aminoacyl transfer ribonucleic acids. Tryptophanyl transfer ribonucleic acid synthetase of Escherichia coli and tryptophanyladenosine triphosphate formation. PMID- 4312459 TI - Chloroquine and synthesis of aminoacyl transfer ribonucleic acids. Conformational changes in tryptophanyl and tryptophan transfer ribonucleic acids. PMID- 4312460 TI - Synthesis of some nucleotides derived from 3'-deoxythymidine. PMID- 4312461 TI - Enzymatic synthesis of deoxyribonucleic acid. XXXIV. Termination of chain growth by a 2',3'-dideoxyribonucleotide. PMID- 4312462 TI - Effect of adenosine monophosphate on the reactivity of thiol groups of D-fructose 1,6-diphosphatase from rabbit liver. PMID- 4312463 TI - A model for the role of metal ions in the enzyme-catalyzed hydrolysis of polyphosphates. PMID- 4312464 TI - Glucokinase of Dictyostelium discoideum. PMID- 4312465 TI - The enzymatic synthesis of hydroxymethyldihydropteridine pyrophosphate and dihydrofolate. PMID- 4312467 TI - Intracellular pH of the peritoneal macrophage effects by silica and by drugs affecting cell metabolism. PMID- 4312466 TI - The acid-soluble nucleotides of the copepod Euchaeta japonica Marukawa. PMID- 4312468 TI - Converting enzyme content of different tissues of the rat. PMID- 4312469 TI - Enhanced synaptic effectiveness following prolonged changes in synaptic use. PMID- 4312470 TI - Glycogenosis type II: glycogen storage in cell cultures from muscle. PMID- 4312471 TI - Calcium dependent corticosteroid release from the perfused cat adrenal gland. PMID- 4312472 TI - Dual localization of beta-glucuronidase and acid phosphatase in lysosomes and in microsomes. II. Membrane-associated enzymes. PMID- 4312473 TI - Anti angiotensin activity of plasma and R.B.C. in cirrhosis of liver and nutritional hypoproteinaemia. PMID- 4312474 TI - Control of citric acid cycle activity in rat heart mitochondria. PMID- 4312475 TI - Allosteric properties of glutaraldehyde-modified glycogen phosphorylase b. Selective desensitization of homotropic cooperativity. PMID- 4312476 TI - Phosphorylation sites, cytochrome complement, and alternate pathways of coupled electron transport in Euglena gracilis mitochondria. PMID- 4312477 TI - An inducible alternate terminal oxidase in Euglena gracilis mitochondria. PMID- 4312478 TI - Biological mechanisms involved in the formation of deoxysugars. VI. Role and function of enzyme-bound nicotinamide adenine dinucleotide in thymidine diphosphate D-glucose oxidoreductase. PMID- 4312480 TI - [Acute hemobilia and hemoperitoneum caused by cancer of the gallbladder]. PMID- 4312479 TI - [Carcinoids of the duodenum. Their relations with Langerhansian tumors and Zollinger-Ellison syndrome]. PMID- 4312481 TI - Microbial culture preservation with silica gel. PMID- 4312482 TI - Sensitivity of Pseudomonas aeruginosa to polymyxin B sulphate and EDTA: role of the divalent cation of the growth medium. PMID- 4312483 TI - A liveborn infant with complete triploidy (69,XXX). PMID- 4312484 TI - [Clinical study on continuous 5-FU infusion for the treatment of primary liver cancer]. PMID- 4312485 TI - [The management of ocular circulatory disturbances with lamuran]. PMID- 4312486 TI - Simple comparison technique for measuring g-values in electron spin resonance spectroscopy. PMID- 4312487 TI - Alteration of the RNA-DNA ratio of rat liver associated with the prevention of AZO dye carcinogenesis by dietary chloramphenicol. PMID- 4312488 TI - Stein-Leventhal syndrome with masculinizing ovarian tumors. Report of 3 cases. PMID- 4312489 TI - [Global results of exfoliative cytology in 200 cases of primary broncho-pulmonary cancer]. PMID- 4312490 TI - [Anatomic substratum of therapeutic effects obtained in chorioepithelioma by hormonal treatment (A.C.T.H. plus estrogens, testosterone plus estrogens)]. PMID- 4312491 TI - [Ocular myopathy. A familial case of oculo-pharyngeal and skeletal muscular dystrophy with late onset]. PMID- 4312492 TI - [Catatonia and catatonic syndromes. Case report]. PMID- 4312493 TI - [Malignant lymphoreticulopathy and toxoplasmosis]. PMID- 4312494 TI - [Nutritional fat intolerance in adults]. PMID- 4312495 TI - [I.V. diazepam in cardiologic practice]. PMID- 4312496 TI - [Beta radiotherapy of eustachian tube swellings. 2500 applications. 23 years' analysis]. PMID- 4312497 TI - [Unusual onset of acute leukemia]. PMID- 4312498 TI - [Significance of the determination of somatotropin in delayed growth]. PMID- 4312499 TI - [Rheumatism and its cardiac localizations in the African Negro (418 cases observed over a 6-year period in Dakar)]. PMID- 4312500 TI - [Sulpiride, an unusual neuroleptic anti-autism and thymoanaleptic drug]. PMID- 4312501 TI - [Rheumatoid polyarthritis in the adult manifesting as agammaglobulinemia]. PMID- 4312503 TI - [Treatment of the chronic coronary insufficiency. 100 cases]. PMID- 4312502 TI - [Phlebothrombosis and magnesium]. PMID- 4312505 TI - [Malabsorption disorders and diarrhea in the diabetic]. PMID- 4312504 TI - [Esophago-gastric disorders in diabetes mellitus]. PMID- 4312506 TI - [Constipation of the diabetic. The paradoxic gastric secretory deficiency syndrome constipation of the diabetic]. PMID- 4312507 TI - [Morphologic abnormalities of the sub-mesocolic digestive tract in the diabetic. Colonic dilatation atony. Gastric secretory deficiency and colonic dilatation atony syndrome]. PMID- 4312508 TI - [Anal disorders in the diabetic]. PMID- 4312509 TI - [Pressure tracings in constant rate hysterography]. PMID- 4312511 TI - Electrophoretic patterns of ribosomal proteins from liver and hepatomas. PMID- 4312510 TI - [Clinical trial of a new sympathoplegic hypotensive agent]. PMID- 4312512 TI - [Lipid composition of the cytoplasmic fractions of Morris hepatoma 5123 and of the liver]. PMID- 4312513 TI - [Distribution of fatty acids in glycerophospholipids of variously differentiated hepatomas]. PMID- 4312514 TI - [Study of the microsomal factors controlling protein synthesis in cell-free systems of liver and hepatoma]. PMID- 4312515 TI - [Oxidation of glutamate in the mitochondria of Yoshida's ascites hepatoma]. PMID- 4312516 TI - Industrial diseases of the central nervous system. PMID- 4312517 TI - [Role of the adrenal glands in the regulation of the kidney activity (literature rediew)]. PMID- 4312518 TI - [Adverse effect of steroid hormone therapy during pregnancy on the embryo and fetus development]. PMID- 4312519 TI - Preliminary evaluation of a decentralized community mental health clinic. PMID- 4312520 TI - Antacids. PMID- 4312521 TI - Facial pain. PMID- 4312522 TI - [What happens when one sleeps?]. PMID- 4312523 TI - Neoplastic transformation of hamster astrocytes and choroid plexus cells in culture by polyoma virus. PMID- 4312524 TI - Comprehensive community mental health centers: a progress report 1969. PMID- 4312525 TI - Intervening in hostile behavior through dyadic and-or group intervention. PMID- 4312526 TI - Teaching through role-play. PMID- 4312527 TI - Utilization of body temperature indicator in psychiatric and geriatric setting. PMID- 4312528 TI - Psychosomatic illness and personality: a brief review of pertinent literature. PMID- 4312530 TI - Accidents--rarely accidental. PMID- 4312529 TI - Intensiveactivity program. PMID- 4312531 TI - Drug abuse--the 1969 social concern. 1. PMID- 4312532 TI - Immunoelectrophoresis of rabbit antisera against phospholipid haptens. PMID- 4312533 TI - Glycolipids from rabbit kidney. PMID- 4312535 TI - [Liaison nurse for Ornskoldsviks hpital]. PMID- 4312534 TI - A critical evaluation and review of ACTH (corticotrophin) in the treatment of acute exacerbations of multiple sclerosis. PMID- 4312536 TI - [The informational stress syndrome]. PMID- 4312537 TI - Progressive multifocal leukoencephalopathy. Identification of virions in paraffin embedded tissues. PMID- 4312538 TI - Cell origin of collagenase in normal and wounded corneas. PMID- 4312539 TI - Open questions in the study of the "trophic" function of the nerve cell. PMID- 4312540 TI - Pneumonia with rapid widespread breakdown of lung tissue. PMID- 4312541 TI - Carbohydrate metabolism in flight muscle of the tsetse fly (Glossina) and the blowfly (Sarcophaga). PMID- 4312542 TI - Corticosteroids9including ACTH) in Crohn's disease. PMID- 4312543 TI - Biosynthesis of amono acids by ruminal microorganisms. PMID- 4312544 TI - Properties of a soluble nitrogenase in Azotobacter. AB - A nitrogenase system that remains in the supernatant fluid after centrifuging for 3 hr at 180,000 x g can be extracted from Azotobacter vinelandii by osmotic lysis of the bacteria. This nitrogenase preparation is oxygen-labile and appears to be similar, though not identical, to that obtained from Clostridium pasteurianum. The particulate characteristic and oxygen stability of previously described preparations are likely due to the method of cell disruption, e.g., in the French pressure cell. The data support a nitrogenase model system in the intact cell in which oxygen-labile enzymes are protected from oxygen by the extensive internal membranous system which Azotobacter synthesize only when they fix nitrogen. PMID- 4312545 TI - 2,4-diaminovaleric acid: an intermediate in the anaerobic oxidation of ornithine by Clostridium sticklandii. AB - The oxidation of ornithine in the presence of proline by crude extracts of Clostridium sticklandii cells was stimulated by nicotinamide adenine dinucleotide, coenzyme A, alpha-ketoglutarate, dimethylbenzimidazolyl cobamide (DBC) coenzyme, MgCl(2), and adenosine diphosphate. Deletion of various cofactors resulted in the accumulation of a new dibasic amino acid which was identified as 2,4-diaminovaleric acid. Both the oxidation of ornithine to alanine and acetate and the conversion of ornithine to 2,4-diaminovaleric acid were stimulated by addition of DBC coenzyme, and both were inhibited by intrinsic factor, an inhibitor of cobamide coenzyme-dependent reactions. This inhibition was reversed by addition of DBC coenzyme. However, the oxidation of 2,4-diaminovaleric acid was insensitive to added intrinsic factor. The data indicate that 2,4 diaminovaleric acid represents the first intermediate in the oxidation of ornithine by C. sticklandii. PMID- 4312547 TI - Biosynthesis of cytidine diphosphate diglyceride by human platelets. AB - Homogenates of human platelets contain an enzyme which catalyzes the formation of cytidine diphosphate diglyceride from cytidine triphosphate and phosphatidic acid. The enzymatic activity could not be dissociated from platelet particles and the greatest specific activity was found in the membrane fraction. The K(m) for cytidine triphosphate was 0.16 mmole/liter and the apparent K(m) for phosphatidic acid was 6.2 mmoles/liter. The pH optimum was 7.0 and the most effective buffers were triethanolamine-HCl and Tris-HCl. The reaction was dependent on the presence of divalent cations, magnesium being the most effective of those investigated. Monovalent cations did not alter the reaction rate. Evidence is presented that the cytidine diphosphate diglyceride produced can serve as a precursor for the synthesis of phosphatidylinositol. No difference was found in the enzymatic activity in platelets from normal subjects and from patients with diseases known to interfere with platelet thromboplastic function. PMID- 4312546 TI - A new method for the measurement of acute alterations in thyroxine deiodination rate in man. AB - A newly devised dual labeled iodine isotopic method is described for the detection and quantitation of alterations in thyroxine (T(4)) deiodination rate in man. This method employs the principle of a constant (125)I infusion to serve as a reference source for the generation of (131)I derived from the deiodination of T(4)-(131)I. Measurement of these two iodide isotopes are made in serially timed urine collections and are expressed in terms of a ratio value. Using this technique, it was possible to measure accurately the effects of a single dose of 6-propylthiouracil (6-PTU) in producing inhibition of T(4) deiodination in euthyroid subjects. It was also possible to assess the time of onset, duration of action, and degree of inhibition produced by 6-PTU. Employing single doses of 6 PTU, ranging from 100 to 1000 mg, there was found to be a log dose relationship with a degree of inhibition observed in T(4) deiodination. In control studies T(4) deiodination rate was found to be constant for periods ranging up to 72 hr in normal ambulating subjects. The acute administration of many other agents was employed in an attempt to alter the T(4) deiodination rate. These included diphenylhydantoin, methimazole, triiodothyronine, thyroxine, thyroid stimulating hormone (TSH), adrenocorticotropin (ACTH), hydrocortisone, predinsolone, potassium iodide, epinephrine, and oxytocin. No detectable change in T(4) deiodination rate was observed with these agents in the dosage ranges employed in this study. The lack of any observable alteration in the T(4) deiodination rate in response to this array of drugs and hormones appears to indicate that the availability of T(4) to intracellular sites of deiodination and possibly action is well modulated to resist abrupt changes. PMID- 4312548 TI - Course of air-borne infection caused by B virus (Herpesvirus simiae). 4. Role of alveolar macrophages of the lungs in inhalation B-virus infection of rabbits. PMID- 4312549 TI - Lymphomatous lesions induced in chickens by cellular inoculum. PMID- 4312550 TI - Electron reactions in gamma-irradiated thymidine and cystamine. PMID- 4312552 TI - Trigeminal sensory neuropathy in connective-tissue disease. PMID- 4312551 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 9-1970. PMID- 4312553 TI - Acetylcholine sensitivity and distribution on mouse neuroblastoma cells. AB - Action potentials resulted from iontophoretic application of acetylcholine to cloned mouse neuroblastoma cells maintained in culture. Cell bodies were sensitive to acetylcholine, but half the cells were insensitive along one of their processes, suggesting an analogy with normal axons and dendrites. Some cells were electrically coupled via their processes, but no chemically mediated synaptic transmission was seen. PMID- 4312554 TI - Overgrowth stimulating factor released from Rous sarcoma cells. AB - An assay is described for a nonzviral factor from the medium of Rous sarcoma cells which stimulates rapid and sustained cellular overgrawth in crowded chick embryo cultures. The factor is nondialyzable and thermnolabile and is released in large amounts several days after the first visible transformation of newly infected chick embryo cells. PMID- 4312555 TI - Primary adenoid cystic carcinoma of the breast. PMID- 4312559 TI - [In vitro synthesis of interferon in various simian tissues]. PMID- 4312560 TI - Ultrastructural features of extramammary Paget's disease. PMID- 4312561 TI - [Histochemistry of capillaries in psoriasis vulgaris]. PMID- 4312562 TI - [Alveolar cell carcinoma]. PMID- 4312563 TI - [The effect of contrast media type on the vascular caliber in experimental angiography]. PMID- 4312564 TI - [The use of a synthetic corticotropin in some forms of epilepsy in childhood]. PMID- 4312565 TI - [Permeation of NAD from the blood stream into the liver cells]. PMID- 4312566 TI - [Scleroderma and alveolar pulmonary carcinoma]. PMID- 4312567 TI - [Histochemical detection of hydrolytic enzymes in Yoshida's sarcoma]. PMID- 4312568 TI - [Modified stroma epithelioma or mixed breast tumor: a case]. PMID- 4312569 TI - [The psychiatric patient in general hospital: intrahospital consultation, inpatient service and after care]. PMID- 4312570 TI - [Current concepts on adenosine cyclic 3',5'-phosphate]. PMID- 4312571 TI - [Therapy of Wilms' tumors in children (38 cases)]. PMID- 4312572 TI - [Vaccination against rubella at the Lariboisiere Hospital]. PMID- 4312573 TI - [Use of progestational hormones in the treatment of advanced stages of breast and gynaecologic carcinoma]. PMID- 4312575 TI - [Glomus tumors of the stomach]. PMID- 4312574 TI - [Synthesis of critical and pathogenic thoughts on the alimentary canal in the diabetic. 190 cases]. PMID- 4312576 TI - [Barre-Masson disease]. PMID- 4312577 TI - [The value of roentgenographic examination in the diagnosis of benign tumors and tumor-like formations of the nasopharynx]. PMID- 4312578 TI - [Use of the Ai variant of deproteinized foot-and-mouth disease virus in the production of vaccine]. PMID- 4312579 TI - [Saponin vaccine from the Ai variant of lapinized foot-and-mouth disease virus]. PMID- 4312580 TI - [Immunobiological properties of vaccine strains of pigeon pox virus]. PMID- 4312581 TI - [Cultivation of erythroblastosis virus in tissue cultures]. PMID- 4312582 TI - [The economic loss caused by the swine pneumonia virus]. PMID- 4312583 TI - [The effect of polymyxin M and chlortetracycline on the motor-secretory function of the stomach in swine]. PMID- 4312584 TI - [The duration of retention of virus in the blood of animals recovering from foot and-mouth disease]. PMID- 4312585 TI - [Contamination of muscle tissue and internal organs of slaughtered animals by Clostridium perfringens]. PMID- 4312586 TI - [Inactivation of foot-and-mouth disease virus in the preparation of a complement fixing antigen]. PMID- 4312588 TI - [The role of the bacterial factor in the etiology of toxic dyspepsia in calves]. PMID- 4312587 TI - [Immunogenic properties of foot-and-mouth disease virus inactivated by various methods]. PMID- 4312589 TI - [Changes in the intestinal microflora of suckling pigs]. PMID- 4312590 TI - [Fractionation of catalase inhibitor isolated from the organs of mice with viral hemocytoblastosis-reticulosis]. PMID- 4312591 TI - [Efficacy of blood and plasma transfusion during the early period of convalescence from infectious hepatitis]. PMID- 4312592 TI - [The use of oxygen in the complex therapy of diseases of the peripheral nervous system]. PMID- 4312593 TI - A new approach to active immunization of sheep by a combined sheep pox and anthrax vaccine. PMID- 4312594 TI - Electron microscopic demonstration of the causative agent of inclusion body rhinitis in pigs. PMID- 4312595 TI - [Comparative studies on the use of the complement fixation test (CF) and serum neutralization test (NT) for diagnosis of parainfluenza-3 (PI-3)-infection of cattle]. PMID- 4312596 TI - Activity of the phenylalanine hydroxylating system in liver of newborn, suckling and adult rats. PMID- 4312598 TI - Biologic and morphologic analysis of growth and cellular pattern of tissues from mice with viral leukemia cultured in vitro. PMID- 4312597 TI - On the release of enzymes upon lysozyme treatment of Streptomyces. PMID- 4312599 TI - Cytochemistry of chronic Nissl disease. PMID- 4312600 TI - [Islet cell adenoma and the intravenous diazoxide test]. PMID- 4312601 TI - [Lysozyme-dependent germination of spores of Clostridium perfringens ATCC 3624 after heat treatment]. PMID- 4312602 TI - [A comparative study of gas produced by 11 anaerobic gas gangrene bacilli grown on a sodium thioglycolate medium, in a vacuum]. PMID- 4312603 TI - [Encephalitogenic activity of Bordetella pertussis]. PMID- 4312604 TI - [Double latent infection with SV5 and herpes viruses in hamster cell culture]. PMID- 4312605 TI - [Isolation and identification of human viruses for diagnostic purposes: results bearing on the years 1961 to 1967]. PMID- 4312606 TI - [The malignancy of epitheliomas with altered stroma called mixed tumors of the submandibular gland. (Apropos of 2 cases)]. PMID- 4312607 TI - [Association of "pneumocystis" pneumonia with a generalized and intrapulmonary cytomegalic inclusion disease. 8 cases]. PMID- 4312608 TI - Purification and properties of two iron-sulfur proteins from Azotobacter vinelandii. PMID- 4312610 TI - Collagenase activity in a particulate fraction from Bacteroides melaninogenicus. PMID- 4312609 TI - A spin label for tyrosine residues. PMID- 4312612 TI - Studies on the nucleotide arrangement in deoxyribonucleic acids. 13. Frequency and composition of purine isostichs in calf-thymus deoxyribonucleic acid. PMID- 4312613 TI - Rous sarcomas in mice: the chromosomal progression in primary tumours. PMID- 4312611 TI - Methylation of transfer RNA and of ribosomal RNA in rat liver in the intact animal and the effect of carcinogens. PMID- 4312614 TI - Rat hepatoma cell surface antigens: demonstration and isolation of membrane associated isoantigens. PMID- 4312615 TI - A shift of liver aldolase towards the muscle type in hepatoma: immunological study. PMID- 4312616 TI - Solubilization and partial fractionation of the sulphur-containing nuclear proteins of hepatoma 223 ascites cells. PMID- 4312617 TI - [Enzyme histochemical studies on experimental glioblastomas in rabbits]. PMID- 4312618 TI - Magnetic susceptibilities of horse erythrocyte catalase and its derivatives in the range from room temperature to 4.2 degrees K. PMID- 4312619 TI - Cytochromes of Bacillus subtilis. 3. Physicochemical and enzymatic properties of cytochromes c-550 and c-554. PMID- 4312620 TI - Effect of parathyroid hormone on rat kidney microsomes in vivo. PMID- 4312621 TI - Stimulation of 14C-leucine incorporation into protein in vitro by rapidly sedimenting nucleolar RNA from AH-130 hepatoma cells. PMID- 4312622 TI - [Bacteriologic problems posed by the ileo-jejuno-colonic transplantation]. PMID- 4312623 TI - Collagenase in bone of man. PMID- 4312624 TI - The intermediate muscle fiber of rats and guinea pigs. PMID- 4312625 TI - Gradient-thickness thin-layer chromatography for the isolation and analysis of trace amounts of free fatty acids in large lipid samples. AB - A thin-layer chromatographic method for quantitative isolation of free fatty acids is described. This method appears to be more satisfactory than existing methods in offering the combination of advantages of specificity, simplicity, rapidity, reproducibility, accuracy, high sensitivity, and applicability as a preparative technique. The method involves chromatography on a thin-layer plate on which the layer of Silica Gel G decreases linearly in thickness from 1000 micro at the base to 125 micro at the upper end. This gradient-thickness design allows the separation and densitometric quantitation of very small traces of free fatty acids from relatively large and complex lipid samples in a single chromatographic step. The method has been shown to be applicable directly to the crude total lipid extracts of several mammalian tissues. It appears to generate little if any artifactual free fatty acids from the breakdown of complex lipids, in contrast to the undesirable behavior of silicic acid columns in this respect. Gradient-thickness thin-layer chromatography promises to be useful for the quantitative isolation of trace amounts not only of other types of lipids but also of classes of compounds other than lipids. PMID- 4312626 TI - Composition of human serum sphingomyelins. AB - Serum sphingomyelins were analyzed by argentation chromatography of the corresponding ceramide diacetates. Six subfractions were obtained. Three of them contained 4-sphingenines in combination with saturated, trans-, or cis-monoenoic fatty acids; the remaining three contained sphingadienine, also in combination with saturated, trans-, or cis-monoenoic fatty acids. Palmitic acid was the principal fatty acid combined with 4-sphingenines, while nervonic acid was the principal fatty acid combined with sphingadienine. About 4% of the total fatty acids of sphingomyelin were trans-monoenoic. They were comprised of many positional isomers of straight-chain C(22-24) compounds. The cis-monoenoic acids made up 33% of the total acids and consisted of almost pure nervonic acid. The rest of the acids were saturated. The 4-sphingenines contained small amounts of iso-C(18) and anteiso-C(19) compounds in addition to the straight-chain C(16-18) bases. PMID- 4312627 TI - Augmentation of pressor response to renin and increased renin release in rats with mercuric chloride intoxication and with bilateral ureteral ligation. PMID- 4312629 TI - [Histological and histochemical changes in the liver in experimental paralytic occlusion of the intestines in a dog]. PMID- 4312628 TI - [Therapeutic possibilities in metastatic cancer of the breast with hypercalcaemia. (Apropos of 2 cases)]. PMID- 4312630 TI - [Crohn's disease involving the colon alone. Apropos of a case]. PMID- 4312631 TI - [2 cases of paradoxal Crohn's disease with banal anal or deceptive rectal onset. Evolutive exacerbations following local manipulations. Ascendent development with late involvement of the ileum]. PMID- 4312632 TI - [Pathologic aspects of Crohn's disease of the colon. Apropos of 3 cases]. PMID- 4312633 TI - [Cytological study of surgical wound drainage fluids after removal of malignant tumors]. PMID- 4312635 TI - [6 purely febrile forms of Hodgkin's disease]. PMID- 4312634 TI - [Chronic gastritis and disseminated polyposis of the stomach associated with a terminal ileitis]. PMID- 4312636 TI - [Goodpasture's syndrome. General review and report of a further case studied by immunofluorescence]. PMID- 4312637 TI - [Diagnostic problems of the Zollinger-Ellison syndrome without ulcer. Apropos of a further case]. PMID- 4312639 TI - [Saint Simon, the good patient]. PMID- 4312638 TI - [The limits of vascular radiology]. PMID- 4312640 TI - [The fetishism of gloves in the last Bourbons]. PMID- 4312641 TI - [Experience in eradicating fowl cholera]. PMID- 4312642 TI - [The effect of selenium on metabolic processes in the chicken]. PMID- 4312643 TI - [Activity of some blood enzymes of breast-fed children in the first month of life and of those receiving additional baby food]. PMID- 4312644 TI - [Effect of pangamic acid on biochemical changes in the blood and tissues of aging organisms during muscular exertion and rest]. PMID- 4312646 TI - [Biological value of hydroponically grown cucumbers and tomatoes]. PMID- 4312645 TI - [The part played by copper and molybdenum in phosphorus-calcium metabolism during rickets (in experiments and clinical practice)]. PMID- 4312647 TI - [Partition chromatography in tracing residual phosphamide in plants]. PMID- 4312648 TI - A particular pharmacological effect on the propagation of experimental strychnine and penicillin epilepsy. PMID- 4312649 TI - Potentiation by angiotensin of responses to endogenously released noradrenaline in the pithed rat. PMID- 4312650 TI - Subcellular fractionation of bovine splenic nerves. PMID- 4312651 TI - Angiotensin and aldosterone in renovascular hypertension. PMID- 4312652 TI - Electron spin resonance measurement on ubiquinone-depleted and ubiquinone replenished submitochondrial particles. PMID- 4312653 TI - The anaerobic interaction of ferrocytochrome c with the "ferric" and "oxygenated" forms of purified cytochrome c oxidase. XVI. Cytochrome oxidase and its derivatives. PMID- 4312654 TI - Oxidative phosphorylation in Azotobacter vinelandii particles. Phosphorylation sites and respiratory control. PMID- 4312655 TI - Oligomycin effects on lipolysis and the oxidative metabolism of brown fat cells. PMID- 4312656 TI - Photoreactions of flavin mononucleotide and a flavoprotein with zwitterionic buffers. PMID- 4312657 TI - Demonstration in vitro of competition between added NADH and glutamate for oxidation by liver mitochondria. PMID- 4312658 TI - Extraction, separation and labeling with 14C-glucose of HeLa cell polyglucose, RNA and DNA and comparison of the molecular weights and buoyant densities of polyglucose from poliovirus-infected and noninfected cultures. PMID- 4312659 TI - Induction of kidney tumours in the rats by feeding Encephalartos hildebrandtii for short periods. PMID- 4312660 TI - Active immunotherapy of L1210 leukaemia applied after the graft of tumour cells. PMID- 4312661 TI - The modification of labeled cytidine and thymidine incorporation into mitochondrial and nuclear DNA in normal liver, hepatoma 3924A and its host liver by isoproterenol. PMID- 4312662 TI - The antigen involved in immune adherence with stratum corneum and human serum. PMID- 4312663 TI - Parainfluenza-3 vaccine in cattle: comparative efficacy of intranasal and intramuscular routes. PMID- 4312664 TI - Epidemiology of vesicular stomatitis virus: some new data and a hypothesis for transmission of the Indian serotype. PMID- 4312665 TI - Moenomycin. VII. Isolation and properties of further components of the antibiotic moenomycin. PMID- 4312666 TI - A reappraisal of copper depletion from cytochrome c oxidase. PMID- 4312667 TI - Cytochrome c oxidase. The bathocuproine effect. PMID- 4312668 TI - Reversible dissociation of tetrameric 7.4 S rabbit muscle glyceraldehyde 3 phosphate dehydrogenase into 4.4 S dimers by' ammonium sulfate and into 3.2 S monomers by KC1. PMID- 4312669 TI - Partial purification and characterization of deoxyribonucleic acid polymerase from KB cells. PMID- 4312670 TI - The isozymes of glutamate-aspartate transaminase. Mechanism of inhibition of dicarboxylic acids. PMID- 4312672 TI - Role of cyclic adenosine 3',5'-monophosphate in the induction of hepatic enzymes. I. Kinetics of the induction of rat liver serine dehydratase by cyclic adenosine 3',5'-monophosphate. PMID- 4312671 TI - The properties of rabbit muscle glyceraldehyde 3-phosphate dehydrogenase labeled with a "reporter group". PMID- 4312673 TI - Pyrimidine biosynthesis de novo in skin. PMID- 4312675 TI - Structure and function of transfer ribonucleic acid. IV. Complexes between valyl transfer ribonucleic acid synthetase and structurally modified transfer ribonucleic acid specific for valine. PMID- 4312676 TI - Preparation and properties of retinal-oxidizing enzyme from rat intestinal mucosa. PMID- 4312677 TI - Synthesis and activity of a new class of heterocyclic compounds against Entamoeba histolytica. 1,2,3,3a-tetrahydro-1-alkylcyclopenta[de]quinolines. PMID- 4312674 TI - Protamine kinase from rainbow trout testis. Partial purification and characterization. PMID- 4312678 TI - Tryptophan and nitrogen metabolism and pregnancy of the rat as affected by dietary supplementations with leucine and with amino acid mixtures. PMID- 4312680 TI - Isolation of a clone of herpes simplex virus highly attenuated for newborn mice and hamsters. PMID- 4312681 TI - Tumor induction in adult mice by SR-RSV material with syngeneic embryo cells. PMID- 4312679 TI - Experimental studies on dynamic behavior of cells in subcutaneous solid tumor (MH 134-C3H-He). PMID- 4312682 TI - Studies on rous sarcoma virus in mice. 3. Three lines of SR-RSV-induced mouse ascites sarcoma. PMID- 4312683 TI - Two cell strains of tissue culture, JTC-15 and -16, from rat ascites hepatomas, AH-66 and -7974. PMID- 4312684 TI - [The biology of dermatophytes. Contributions of electron microscopy to the enzymatic cytochemistry and biochemistry]. PMID- 4312685 TI - Intradural granulomatous neuritis. Report of cases of granulomatous neuropathy of v, xii and ix cranial nerves and of cauda equina. PMID- 4312686 TI - Successful pregnancy in a patient with Sheehan's syndrome. PMID- 4312687 TI - [Granular cell myoblastoma]. PMID- 4312689 TI - [Therapy of necrotizing herpesvirus encephalitis using idoxuridine]. PMID- 4312688 TI - [Electron microscope study of 2 traumatic neuromas]. PMID- 4312690 TI - Interstitial nephritis in a dog associated with infectious canine hepatitis virus. PMID- 4312691 TI - [Polydysplasia with macular dermal hypoplasia]. PMID- 4312692 TI - [Paget's disease of the breast. Electron microscope study of 2 cases]. PMID- 4312693 TI - [The erythro-squamous lesions of the hands in cement workers]. PMID- 4312694 TI - [Enzyme changes in the cytoplasm of cells (established-line) infected by type 5 adenovirus I. Enzymes in noninfected cells]. PMID- 4312695 TI - [Enzyme changes in the cytoplasm of cells (established T line) infected by type 5 adenovirus. 2. Enzymes in infected cells]. PMID- 4312696 TI - A modified method for the isolation of the plasma membrane from rat liver. PMID- 4312697 TI - The solubilization and gel electrophoresis of membrane enzymes by use of detergents. PMID- 4312699 TI - [On an unusual case of adenocystic carcinoma of the breast]. PMID- 4312698 TI - [Inhibition of oxytocin effects on frog skin and bladder by (2-O-ethyltyrosine) oxytocin]. PMID- 4312700 TI - [Demonstration of paradoxal sleep in utero in guinea pigs]. PMID- 4312701 TI - [Tumors of the carotid body]. PMID- 4312702 TI - [Effect of imipramine, dexphenmetrazine and amphetamine sulfate on synchronous and paradoxical sleep in narcolepsy-cataplexy. A polygraphic study]. PMID- 4312703 TI - Inhibition of rat liver adenyl cyclase by adenosine and adenine nucleotides. PMID- 4312704 TI - Collagenolytic enzymes in human serum. PMID- 4312705 TI - The effect of abdominal wounding on the rate of tissue regeneration. PMID- 4312706 TI - The effect o angiotensin II on the platelet aggregation induced by adenosine diphosphate, epinephrine and thrombin. PMID- 4312708 TI - [Immunological aspects of ACTH]. PMID- 4312707 TI - [Simple methods for the quantitative evaluation of blackening in histophotography]. PMID- 4312709 TI - [Multiple malformations in a newborn infant presenting a chromosomic triploidy]. PMID- 4312710 TI - [89 operated bronchopulmonary cancers in women]. PMID- 4312711 TI - Effects of hyperbaric oxygenation on metabolism. VI. Efficacy of protective agents at 5,7,9, and 11 atmospheres of 100 percent oxygen. PMID- 4312712 TI - Influence of synthetic double-stranded ribonucleic acid (poly I:C) on SV40 viral oncogenesis and transplant tumor in hamsters. PMID- 4312713 TI - Effect of hyperphysiological levels of hexestrol on the hepatic metabolism of nicotinate in the mouse. PMID- 4312714 TI - Occurrence of phentypically mixed viruses in the Bryan high-titer strain of Rous sarcoma virus and RSV (RAV-1) stocks. PMID- 4312715 TI - Studies on interferon induction by the mouse mammary tumor virus. PMID- 4312717 TI - Rhinovirus replication in suspension cultures of HeLa cells. PMID- 4312716 TI - Antigenic variation of rhinovirus type 22. PMID- 4312718 TI - [Arrhenoblastoma in pregnancy with delivery of a female fetus]. PMID- 4312719 TI - [Study of iron metabolism in rats with transplantable tumors]. PMID- 4312720 TI - [Some oxidizing-reducing enzymes in the cerebrospinal fluid in otogenic intracranial complications]. PMID- 4312721 TI - [Clinical aspects and diagnosis of pharyngitis in adults with parainfluenzal diseases]. PMID- 4312722 TI - [Treatment of chronic dermatoses with steroids]. PMID- 4312723 TI - [Functional condition of adrenal cortex in sick premature infants]. PMID- 4312724 TI - [Some indices of lipid metabolism in children and adolescents with hypertension]. PMID- 4312725 TI - [Virulogical and serological indices in children with different postvaccinal complications]. PMID- 4312726 TI - Histochemical studies on the effect of imuran on the muscular phase of trichinellosis in mice. PMID- 4312727 TI - Pathomorphology of muscular trichinellosis in comparative histological, histochemical, ultrastructural, autoradiographic and immunofluorescent investigations. PMID- 4312728 TI - Decreased aldosterone production by rat adrenal tissue in vitro due to treatment with 9-alpha-fluorocortisol, dexamethasone and adrenocorticotrophin in vivo. PMID- 4312729 TI - Biosynthesis of adrenal corticosteroids: energy metabolism and the hydroxylases. PMID- 4312730 TI - Deoxycytidylate deaminase and related enzymes of thymidine triphosphate metabolism in hepatomas and precancerous rat liver. PMID- 4312732 TI - Ultrastructure of the glomus jugulare tumor. PMID- 4312733 TI - [Viruses as causal agents of disease]. PMID- 4312734 TI - [Punched-card documentation at the post care of chronic diseases]. PMID- 4312735 TI - Pharmacological redundancy as an adaptive mechanism in the central nervous system. PMID- 4312731 TI - [Terminological problems in glomus tumors]. PMID- 4312736 TI - Effects of antilymphocytic serum on bacterial and viral infections and virus oncogenesis. PMID- 4312737 TI - Effects of antilymphocytic serum on host responses to infectious agents. PMID- 4312738 TI - Effects of antilymphocyte serum on the induction of neoplasms of lymphoreticular tissues. PMID- 4312740 TI - Acute tapioca poisoning in a child. PMID- 4312739 TI - Oestrogen metabolism in liver disease. PMID- 4312741 TI - [The renin--angiotensin--aldosterone system]. PMID- 4312742 TI - The lipids of mitochondria of human gray and white matter. PMID- 4312743 TI - Molecular species of phosphatidyl ethanolamine from egg yolk. PMID- 4312744 TI - Gas liquid chromatographic analysis of sphingosine bases in sphingolipids of human normal and multiple sclerosis cerebral white matter. PMID- 4312745 TI - Phospholipid class and fatty acid composition of developing spinal cord in normal pigs and in congenital tremor (Myoclonia congenita). PMID- 4312746 TI - Evidence for a role of cyclic AMP in neuromuscular transmission. AB - Experiments were undertaken to determine if the effects of epinephrine in promoting neuromuscular transmission were mediated by adenosine 3':5'-cyclic phosphate (cyclic AMP). Dibutyryl cyclic AMP and the methyl xanthines, theophylline and caffeine (which inhibit cyclic AMP hydrolysis), were found to increase the amplitude of the end plate potential in the isolated rat diaphragm. Like epinephrine (which is known to promote cyclic AMP synthesis), these agents appear to facilitate the release of acetylcholine from the motor neuron. This interpretation is supported by the observation that theophylline and dibutyryl cyclic AMP markedly increased the frequency but not the amplitude of the spontaneous miniature end plate potentials. In addition, these drugs increased the number of transmitter packets released in response to nerve stimulation. These results are consistent with the view that cyclic AMP plays a role in the release of acetylcholine and in the "defatiguing effect" of epinephrine. PMID- 4312747 TI - Orientation of lipid spin labels in lecithin multilayers. AB - Nitroxide-labeled stearic acid and cholestane have been incorporated into lecithin multilayers. The pronounced anisotropy of the preparations reflects a nonrandom structure of the lecithin film and demonstrates that these lipid probes can report structural information from lipid regions resembling those thought to occur in membranes. These two probes differ with respect to the orientation of the NO bond to the long axis, but both orient with their long axes perpendicular to the phospholipid film. Simulated spectra, calculated on the basis of a Gaussian distribution of orientations, are in agreement with the experimental results. PMID- 4312748 TI - Electron spin resonance of irradiated single crystals of L-phenylalanine-HCl. AB - Single crystals of L-phenylalanine-HCl have been observed with electron spin resonance after irradiation with a cobalt 60 gamma-ray source. The predominant signals observed are from long-lived benzyl radicals. The results indicate that one form of radiation damage to proteins containing this amino acid is breakage of the carbon-carbon bond to release the benzyl radical from the polypeptide chain. Hyperfine structure due to proton couplings of the two methylene hydrogens and of the hydrogens on the ring of the benzyl radical is observed and analyzed to give the electron spin density on the various carbons. The spin density on the methylene carbon is found to be 0.71; that on carbon C((2)), C((4)), or C((6)) is 0.17. The sum of the spin densities on C((1)), C((3)), and C((5)) is -0.22. PMID- 4312749 TI - Orientation and motion of amphiphilic spin labels in membranes. AB - The paramagnetic resonance spectra of N-oxyl-4','-dimethyloxazolidine derivatives of 12-ketostearic acid, 5-ketostearic acid, 5-ketotricosanoic acid, and 5alpha androstan-3-one-17beta-ol have been observed in sonicated phospholipid dispersions, the walking-leg nerve fibers of Homarus americanus, and in erythrocytes oriented by hydrodynamic shear. The preferred orientation of these spin labels in the nerve and erythrocyte membranes is one in which the long amphiphilic axis is perpendicular to the membrane surface. The resonance spectra indicate that these labels in the nerve fiber are bound to a lipid bilayer very similar to that found in the sonicated phospholipid dispersion, whereas any lipid bilayer in the erythrocyte must be much more rigid. PMID- 4312750 TI - Magnetic resonance studies of spin-labeled creatine kinase system and interaction of two paramagnetic probes. AB - Creatine kinase from rabbit muscle has been specifically labeled with a derivative of a nitroxide free radical on the two essential sulfhydryl groups, one per active site. The conformation in the environment of the enzyme-bound free radical and the change in conformation induced upon binding of the substrate, metal adenosine diphosphate, has been monitored by two parameters of the bound spin label, its electron paramagnetic resonance spectrum and its contribution to the proton relaxation rate of water. The specificity in activation of the enzymic reaction of the series of alkaline earth ions, Mg, Ca, Sr, Ba, was not reflected by differences in conformation of the ternary enzyme metal substrate complexes observable with the spin probe. However, with the inhibitory zinc ion, the conformation of ternary complex was distinctly different. The electron paramagnetic resonance spectra of complexes with two paramagnetic probes, namely, spin-labeled enzyme with paramagnetic metal adenosine diphosphate complexes (Mn(II), Ni(II), and Co(II)) revealed a spin-spin interaction between the protein bound free radical and the paramagnetic metal ions. From the magnitude of the interaction, the distance between the manganous ion and the electron spin of the nitroxide moiety in the MnADP-spin-labeled creatine kinase was estimated to be in the range of 7-10 A. PMID- 4312751 TI - Alpha-keto acid dehydrogenase complexes. XI. Comparative studies of regulatory properties of the pyruvate dehydrogenase complexes from kidney, heart, and liver mitochondria. AB - The activity of the multienzyme pyruvate dehydrogenase complexes, isolated from mitochondria of beef kidney, beef heart, and pork liver, is regulated by phosphorylation and dephosphorylation. Phosphorylation and concomitant inactivation of each of the three complexes are catalyzed by an ATP-specific kinase, and dephosphorylation and concomitant reactivation are catalyzed by a phosphatase. The phosphatase has been separated from the other component enzymes of each pyruvate dehydrogenase complex, and the three phosphatases are functionally interchangeable. The kinase has been isolated from the beef kidney complex, and it is functional with the beef heart and pork liver complexes. ADP is competitive with ATP, and the ADP effect is more pronounced with the kidney kinase than with the liver and heart kinases. Pyruvate protects strongly the heart and liver pruvate dehydrogenase complexes and, to a lesser extent, the kidney complex against inactivation by ATP. Pyruvate apparently exerts its effect on the pyruvate dehydrogenase component of the complex, rather than on the kinase. PMID- 4312752 TI - The acrasin activity of 3',5'-cyclic nucleotides. AB - 3',5'-Cyclic nucleotides are acrasins for the cellular slime mold, Dictyostelium discoideum; they have chemotactic activity on the myxamoebae at very low concentrations. However, not all cyclic nucleotides can evoke the adhesiveness necessary for aggregate formation. 2',3'-Cyclic nucleotides and dibutyrylcyclic adenosine monophosphate are not acrasins, though they enhance the rate of differentiation and morphogenesis. The addition of 3',5'-cyclic nucleotides to agar test plates stimulates the rate of morphogenesis. While the stimulatory effect of cyclic nucleotides is concentration-dependent, it is fairly uniform between pH 5 and 7, with an optimum at pH 6. The acrasins may be metabolized by extracellular phosphodiesterase to 5'-nucelotides which may then stimulate differentiation and morphogenesis. PMID- 4312753 TI - Rates of GDP-induced and GTP-induced depolymerization of glutamate dehydrogenase: a possible factor in metabolic regulation. AB - The rate of the depolymerization of beef liver glutamate dehydrogenase induced by coenzyme and the purine nucleotides guanosine 5'-diphosphate and guanosine 5' triphosphate, which are potent inhibitors of enzymatic activity, has been measured by rapid light scattering techniques and by absorbancy changes with stop flow. It is shown that the rate constant for this process may vary from several milliseconds to several seconds depending upon the nucleotides used. The widely varying rate constants for the nucleotide-induced depolymerization may serve a role in determining the nature of the regulation of enzyme activity by nucleotides. Depolymerization induced by guanosine 5'-diphosphate in the presence of diphosphopyridine nucleotide is slower than in the presence of triphosphopyridine nucleotide as coenzyme, and this difference is apparently due to the isomerization of the enzyme as a result of diphosphopyridine nucleotide binding to a second, nonactive site. This binding, as well as binding of the coenzyme to the active site, may be conveniently measured by a purine nucleotide induced spectral shift in the coenzyme absorption spectrum. It is also shown that complete depolymerization of the enzyme in the presence of guanosine 5' triphosphate is accomplished by about half saturation of the coenzyme active sites (6-8 active "monomer"). PMID- 4312754 TI - Foot-and-mouth disease virus inhibition induced in mice by synthetic double stranded RNA (polyriboinosinic and polyribocytidylic acids). AB - Synthetic 2-stranded RNA-a helical complex formed by duplexing homopolymers of polyriboinosinic and polyribocytidylic acids (poly I:C)-induced host resistance to foot-and-mouth disease virus when microgram quantities were injected into mice. There was a graded response as shown by titrations of polynucleotide complex or virus. Protection was effective for >48 hours after a single injection of polynucleotide complex. Survival and serum interferon titers were directly related. PMID- 4312755 TI - Mouse leukemia virus: "spontaneous" release by mouse embryo cells after long-term in vitro cultivation. AB - BALB/c mouse embryo cells maintained in tissue culture on a schedule of rapid transfer at high cell density develop into tumorigenic lines that have lost contact inhibition of cell division. After several months in culture, certain of these lines begin to release mouse leukemia virus. This virus has properties indistinguishable from those of virus found in adult BALB/c mice. The evidence presented here demonstrates that the murine leukemia virus genome must be present in the original embryo cultures. The possibility that the genetic information for making murine leukemia virus is present in a repressed form in every mouse embryo cell is discussed. PMID- 4312756 TI - Radical transformation in irradiated DNA and its constituents. AB - Electron spin resonance spectroscopy has been used to study transformation of radicals in DNA and a number of its constituents. It was found that in all the bases irradiated at 77 degrees K, hydrogen-addition radicals were formed on warming. The following mechanism of radical transformation has been proposed: damaged species, probably ion-radicals, release hydrogen atoms on warming, which then add to the undamaged bases, preferentially thymine. Thymine need not be the place of the primary damage. PMID- 4312758 TI - [Dynamics of cutaneous histochemical changes during the development of experimental precancerous conditions]. PMID- 4312757 TI - [Biological activity of the products of phototransformation of rat skin sterols]. PMID- 4312759 TI - [Methodological substantiation of indication of viruses of the avian leukosis group]. PMID- 4312760 TI - [Assessing postvaccinal immunity to pox in birds]. PMID- 4312762 TI - [Activity of hexokinases at different stages of malignant degeneration of the liver]. PMID- 4312761 TI - [Biochemical characteristics of bacteriophage SW]. PMID- 4312763 TI - [Effect of high energy radiation on the activity of cytochrome oxidase and succinate dehydrogenase in liver mitochondria and heart muscle of rats]. PMID- 4312764 TI - [Determination of lecithinase activity in Clostridium perfringens by its action upon liver lysosomes in rats]. PMID- 4312765 TI - [Therapy of pulmonary tuberculosis with reserve drugs in the light of our personal observations]. PMID- 4312766 TI - [Clinical findings and therapy of stomach carcinoma developing from stomach ulcer]. PMID- 4312767 TI - [Pathogenesis, clinical findings and prognosis of giant fibroadenoma of the female breast]. PMID- 4312768 TI - [Malignant synovialoma and trauma (a problem of expert opinion)]. PMID- 4312769 TI - Lipid composition of adenovirus-induced tumor. PMID- 4312770 TI - Enzyme changes in the hereditary ataxic rabbit. PMID- 4312771 TI - [Biopsy findings on the T-system and tubular structures in neoplastic cortisone myopathy]. PMID- 4312772 TI - Rate and ways of resolution of hypertensive vascular disease. PMID- 4312773 TI - [Pathological study of toxic polyneuropathy. (I). Experimental induction of polyneuropathy by methylmercury]. PMID- 4312774 TI - Infectious mononucleosis in acute leukemia with rising Epstein-Barr virus antibody titers. PMID- 4312775 TI - Enzymatic control of the metabolic activity of Pseudomonas aeruginosa grown in glucose or succinate media. PMID- 4312776 TI - The effect of ethionine on hepatic gluconeogenesis in the rat. PMID- 4312778 TI - Evidence for a functional pyridine nucleotide cycle in Escherichia coli. PMID- 4312777 TI - The influence of polyenes on cyclic 3',5'-AMP formation and glucose utilization in thyroid. PMID- 4312779 TI - Isolation and identification of a paramagnetic complex from the livers of carcinogen-treated rats. PMID- 4312780 TI - The redox state of the mitochondrial NAD system in cirrhosis of the liver and in chronic quantitative undernutrition in the rat. PMID- 4312781 TI - Developments in steroidal hormonal contraception. PMID- 4312782 TI - [Medio-facial giant cell reticulo-histiocytoma]. PMID- 4312783 TI - [Passage of cortisol in unaltered and unconjugated form into the urine in central type of Cushing's syndrome and in Addison's disease at different levels of ACTH in the organism]. PMID- 4312784 TI - Intracellular localization of phosphodiesterases I and II in rat liver. PMID- 4312785 TI - A method for the large scale preparation of the avian erythrocyte specific histone F2C. PMID- 4312786 TI - Interconversion in vitro of two forms of liver phosphorylase phosphatase. PMID- 4312787 TI - The immunochemistry of Shigella flexneri O-antigens. The structure and biosynthesis of the O-specific side chains of some representative serotypes. PMID- 4312788 TI - The activation of phosphorylase in neonatal rat liver. PMID- 4312789 TI - Carcinomas of the glandular stomach and other organs of rats induced by 4 hydroxyaminoquinoline 1-oxide hydrochloride. PMID- 4312790 TI - NAD biosynthesis in rabbit erythrocytes and reticulocytes after whole-body x irradiation. PMID- 4312791 TI - Synthesis and release of proinsulin and insulin by human insulinoma tissue. PMID- 4312792 TI - A case of a partial defect of the iodide trapping mechanism. PMID- 4312793 TI - Factors influencing the urinary excretion of 3',5'-adenosine monophosphate in humans. PMID- 4312795 TI - Secretion rates of cortisol and aldosterone precursors in various forms of congenital adrenal hyperplasia. PMID- 4312794 TI - Malignant lipid cell tumor of the ovary: clinical, biochemical and etiologic considerations. PMID- 4312796 TI - Effect of hormones on the biosynthesis of nicotinic acid from tryptophan in man. PMID- 4312797 TI - Asymptomatic cytomegalovirus infection following blood transfusion in tumor surgery. PMID- 4312798 TI - Virologic study on an outbreak of infantile diarrhea. PMID- 4312799 TI - Attempts at analysis of toxicity of pertussis vaccine. II. Quantitative determination of the heat-labile toxin by skin reaction. PMID- 4312800 TI - [Carcinoma of the anus and its TNM classification]. PMID- 4312802 TI - Is it bad to be blue? PMID- 4312801 TI - Myelography. Past and present (1935-1968). PMID- 4312803 TI - Mucoid bone marrow without carcinoma deposits. PMID- 4312804 TI - Planning the appropriate operations for islet cell tumors of the pancreas. PMID- 4312805 TI - [Diagnosis, differential diagnosis and therapy of synovialoma]. PMID- 4312806 TI - Intradiscal measurements of pH in patients with lumbar rhizopathies. PMID- 4312807 TI - [Indications, in anesthesia and resuscitation, for various analeptics during cardiogenic shock]. PMID- 4312809 TI - [Cytochemical study of 5l sub-retinal fluids]. PMID- 4312808 TI - [Indications, in anesthesia-resuscitation, for various analeptics during obstetrical shock]. PMID- 4312810 TI - [Periodate reaction of amines. 5. Glycol cleavage reagents]. PMID- 4312811 TI - [Injury and brain tumor]. PMID- 4312812 TI - A direct thiobarbituric acid-reacting chromogen in human red blood cells. PMID- 4312813 TI - Plasma phospholipids in cirrhosis of liver and fatty liver. PMID- 4312815 TI - Proposition for an international angiotensin standard for renin measurement in human plasma. PMID- 4312814 TI - Serum hyaluronidase activity in chronic liver damage. PMID- 4312816 TI - [Some indicators of organic reactivity in acute respiratory diseases in children]. PMID- 4312817 TI - [Intravenous angiotensin test in the differential diagnosis of arterial hypertension]. PMID- 4312818 TI - [The role and significance of molybdenum in the life of organisms]. PMID- 4312819 TI - [Role of the endocrine system in the regulation of the permeability of the hemato labyrinth barrier]. PMID- 4312820 TI - [Effect of ACTH on some aspects of lipid metabolism in normal and adrenalectomized animals]. PMID- 4312821 TI - Neuropathology. PMID- 4312822 TI - General neurophysiology (biochemical aspects). PMID- 4312823 TI - Peripheral nerve surgery. PMID- 4312824 TI - Psychoanalysis. PMID- 4312825 TI - Regional physiology of the nervous system. PMID- 4312826 TI - [Effect of one of the basal proteins of the brain on the activity of some enzymes]. PMID- 4312827 TI - [Carbohydrate metabolism in the liver of fetuses and adult pigs]. PMID- 4312829 TI - [Ultrastructure of capillary walls during the passage of contrast medium particles under prolonged administration of ACTH]. PMID- 4312828 TI - [Gluco-mineralocorticoids in correction of electrolyte balance and corticosteroid excretion disorders in the surgical treatment of nephrolithiasis]. PMID- 4312830 TI - [Clinical-anatomical observations in malignant beta-cell tumors of the pancreas]. PMID- 4312831 TI - [Myoblastomyoma of larynx]. PMID- 4312832 TI - [Diagnosis of tuberculosis in birds with Rous sarcoma]. PMID- 4312833 TI - [Enzymatic activation of liver antigens reacting with normal and anti-hepatoma antibodies in mice]. PMID- 4312834 TI - [Disorders of the functional state of the adrenal cortex in precancerous diseases and cancer of the stomach]. PMID- 4312836 TI - [Dynamics of virus accumulation and electron microscopic demonstration of virus particles in cultures infected with avian leukosis virus]. PMID- 4312835 TI - [Improvements in the methods of diagnosing and treating trophoblastic disease]. PMID- 4312837 TI - [Evaluation of esophago- and gastro-intestinal anastomoses constructed with suturing apparatuses]. PMID- 4312839 TI - [Involvement of peripheral nervous system in tuberculosis]. PMID- 4312838 TI - [Virological diagnosis of adenoviral and paragrippous diseases]. PMID- 4312840 TI - [Course of concomitant diseases in patients with different phases of diabetes mellitus]. PMID- 4312841 TI - [Experimental studies of fibrinogenicity of amorphous silica--aerosil M-300]. PMID- 4312842 TI - [2 kinds of sleep]. PMID- 4312843 TI - Arginine in viomycin biosynthesis. PMID- 4312844 TI - Myelin constituents of human central nervous system. PMID- 4312845 TI - [Epidemiologic findings on Pseudomonas aeruginosa in a premature infant department by the cytochrome oxidase test]. PMID- 4312846 TI - [Adrenocorticotropic reaction to the administration of etiocholanolone]. PMID- 4312847 TI - Collagenase from rat uterus. Isolation and partial characterization. PMID- 4312848 TI - Modulation of heart muscle mitochondrial malate dehydrogenase activity. I. Activation and inhibition by p-mercuribenzoate. PMID- 4312849 TI - Modulation of heart muscle mitochondrial malate dehydrogenase activity. II. p Mercuribenzoate activation, model of a possible allosteric control mechanism for substrate homeostasis. PMID- 4312850 TI - Characterization of antibodies of high affinity and specificity for the digitalis glycoside digoxin. PMID- 4312853 TI - Differential levels of stage IV sleep in a group of clinically similar chronic schizophrenic patients. PMID- 4312852 TI - Amino acid transfer factors from yeast. 3. Relationships between transfer factors and functionally similar protein fractions. PMID- 4312851 TI - The degradation of trans-ferulic acid by Pseudomonas acidovorans. PMID- 4312855 TI - The maximal capacity for sleep: rapid eye movement density as an index of sleep satiety. PMID- 4312856 TI - Neurohumoral aspects of sleep control. PMID- 4312854 TI - Neuronal activity during wakefulness and sleep: some comments. PMID- 4312857 TI - REM deprivation and schizophrenia. PMID- 4312858 TI - Cerebral amino acids during deprivation of paradoxical sleep. PMID- 4312859 TI - Efficiency of verbal learning during sleep as related to the EEG pattern. PMID- 4312860 TI - The sensitivity of cortical neurones to acidic amino acids and acetylcholine. PMID- 4312861 TI - Effect of angiotensin and atropine on the spontaneous release of acetylcholine from cat cerebral cortex. PMID- 4312862 TI - The effect of moderate hypoxia and ischemia on cytochrome oxidase activity and protein synthesis in brain mitochondria. PMID- 4312863 TI - The postsynaptic inhibition of rabbit oculomotor neurones by secondary vestibular impulses and its blockage by picrotoxin. PMID- 4312864 TI - Post-tetanic potentiation at the neuromuscular junction of the frog in the presence of tetrodotoxin. PMID- 4312865 TI - Influence of age on experimental cutaneous calcification. PMID- 4312866 TI - Regulation and mechanism of phosphoribosylpyrophosphate synthetase. II. Excchange reactions catalyzed by the enzyme. PMID- 4312867 TI - Adrenocorticotropin stimulation of 2-ketoglutarate oxidation by isolated rat epididymal adipose tissue. Mediation by cyclic adenosine 3',5'-monophosphate and relationship to lipid metabolism. PMID- 4312868 TI - Catalytic facilitation in vitro by two multienyzme complexes from Neurospora crassa. PMID- 4312869 TI - The diphtheria toxin-dependent adenosine diphosphate ribosylation of rat liver aminoacyl transferase. II. General characteristics and mechanism of the reaction. PMID- 4312870 TI - Electron paramagnetic resonance spectra of manganese (II)-protein complexes. Manganese (II)-concanavalin A. PMID- 4312871 TI - A prospective study of chronic herpes simplex virus infection and recurrent herpes labialis in humans. PMID- 4312872 TI - Evidence for tolerance to SV40 tumor antigen in hamsters bearing para-adenovirus 12 tumor transplants. PMID- 4312874 TI - Immunochemical studies of foot-and-mouth disease. VI. Differences in antigenic determinant site recognition by guinea pig 19S and 7S antibodies. PMID- 4312873 TI - A reaginic type of antibody stimulated by extracts of Bordetella pertussis in inbred strains of mice. PMID- 4312875 TI - Measurement of antibody against human IgG by the neutralization of IgG-sensitized herpes simplex virus. PMID- 4312876 TI - Phospholipids in cultured guinea pig skin. PMID- 4312877 TI - [Panmyelopathy after viral hepatitis]. PMID- 4312878 TI - Effects of black widow spider venom on the frog neuromuscular junction. Effects on end-plate potential, miniature end-plate potential and nerve terminal spike. PMID- 4312879 TI - Effects of black widow spider venom on the frog neuromuscular junction. Effects on the fine structure of the frog neuromuscular junction. PMID- 4312880 TI - Probable occurrence of infectious bovine rhinotracheitis virus in Tanzania in wildlife and cattle. PMID- 4312881 TI - Comparative studies of gliomas in vitro and in vivo. PMID- 4312882 TI - Grades of malignancy of tumours of neuroectodermal origin. PMID- 4312883 TI - Lung cancer in the Hungarian plain. PMID- 4312884 TI - [The effect of ACTH on the plasma steroid level in the trained and untrained organism]. PMID- 4312885 TI - [Clinical and laboratory findings in delayed puberty in boys]. PMID- 4312886 TI - [The Kaplan-Silah angiotensin test]. PMID- 4312887 TI - [Electronic paramagnetic resonance (EPR) in biology and medicine]. PMID- 4312888 TI - [Subunit structure of FDP--aldolase]. PMID- 4312889 TI - [Progress in studies on the molecular mechanism of the infection cycle of poxviruses]. PMID- 4312890 TI - Outbreak of Hong Kong influenza in Milwaukee, winter of 1968-69. PMID- 4312891 TI - [Effects of hormones on intestinal lipolysis]. PMID- 4312892 TI - [A case of aneurysm of the aorta associated with cytomegalic inclusion disease in newborn infants]. PMID- 4312893 TI - [Congenital and acquired cytomegalic disease]. PMID- 4312894 TI - Lung cancer among the Jews. PMID- 4312896 TI - Irradiation of the liver in children: review of experience in the acute and chronic phases, and in the intact normal and partially resected. PMID- 4312895 TI - Moving strip irradiation in the treatment of extensive neoplastic disease in the chest. PMID- 4312897 TI - Calcification of the basal ganglia following radiation therapy. PMID- 4312898 TI - Babesia rodhaini: carbohydrate metabolism and infectivity for rats of cells freed from host erythrocytes. PMID- 4312899 TI - [Adrenocortical function in liver diseases]. PMID- 4312900 TI - The use of sulphite-containing media in the isolation of Clostridium welchii. PMID- 4312901 TI - Separation of conjugated urinary estrogens on columns of sephadex. I. Optimization of conditions. PMID- 4312902 TI - [Symposium on asthma. Effect of air pollution upon bronchial asthma]. PMID- 4312904 TI - To sleep: to die. PMID- 4312903 TI - The pharmacology of disordered sleep. A laboratory approach. PMID- 4312905 TI - Pharmacologic and physiologic aspects of anesthesiology. II. PMID- 4312906 TI - [Value of the Kaplan-Silah angiotensin infusion test in the etiologic diagnosis of arterial hypertension]. PMID- 4312907 TI - [Immunomorphologic reactions of the lungs during tuberculosis inflammation caused by mycobacteria with attenuated virulence (according to histochemical and electron microscopic findings)]. PMID- 4312908 TI - Labelling of antigens by various isotopes. PMID- 4312909 TI - Studies on mycobacterial sensitizing fractions. IV. Fractionation of components of unheated M. tuberculosis and BCG culture filtrates by successive precipitation with CH3COOH, HClO4 and CCl3COOH. PMID- 4312910 TI - Elucidation of factor(s) responsible for growth stimulation in Entamoeba histolytica. PMID- 4312911 TI - The transfer function of frog myoneural junctions. II. The influence of previous conditions in situ upon the invitro responses to pulse trains. PMID- 4312912 TI - Left ventricular function during the early and late stages of scar formation following experimental myocardial infarction. PMID- 4312913 TI - Selective inhibition by chloramphenicol of ACTH-induced reorganization of inner mitochondrial membranes in fetal adrenal cortical cells in tissue cultures. PMID- 4312915 TI - An experimental approach to dreams and telepathy. II. Report of three studies. PMID- 4312914 TI - Sleep disturbance in acute schizophrenic patients. PMID- 4312916 TI - Angiotensin converting enzyme: method of assay and partial purification. PMID- 4312917 TI - Micro procedure for determination of pyrophosphate and orthophosphate. PMID- 4312918 TI - Microdetermination of guanine ribonucleotides by an enzymic amplification technique. PMID- 4312919 TI - A new spectrophotometric micro determination of vicinal diols. PMID- 4312921 TI - Combined screw-cap and rubber-stopper closure for Hungate tubes (pre-reduced anaerobically sterilized roll tubes and liquid media). AB - A double-closured method introduced for Hungate tubes eliminates clamps or special racks to hold the rubber stoppers in place while the tubes are being processed. The system prevents stoppers from being dislodged by gas-producing anaerobes and keeps the stoppers sterile so that the closed system of transfer can be conveniently utilized. Open and closed systems for handling a gas producing anaerobe were compared. Ten tubes containing Clostridium perfringens were opened; the organism was detected in the air by use of an impingement collector. The gloved hand of the operator also revealed the test organism. A similar trial with culture material removed by the closed system (syringe transfer) resulted in no detectable contamination of the environment. PMID- 4312920 TI - Cytomegalovirus in the inner ear. Case report and electron microscopic study. PMID- 4312922 TI - Role of interferon in the propagation of MM virus in L cells. AB - MM virus propagated in mouse brain replicates to low titers in L cells without production of cytopathic effect (CPE). After growing the virus in BHK-21 cells, however, the virus replicates to high titers in L cells with complete CPE. It was found that suspensions of MM virus propagated in L cells directly from the mouse brain contained much more interferon than did suspensions of virus which had first been grown in BHK-21 cells. Mouse brain suspensions of the virus were also found to contain high interferon titers. Treatment of L cells with actinomycin D before infection with mouse brain-grown virus resulted in full virus replication with CPE. BHK-21 cell-grown virus diluted in L cell interferon behaved like mouse brain-grown virus in L cells. It is concluded that the presence of interferon in the inoculum is largely responsible for the suppression of MM virus replication in L cells. PMID- 4312923 TI - Bordetella pertussis serotypes in the United States. AB - To determine the Bordetella pertussis serotypes currently causing whooping cough in the United States, recently isolated cultures from different geographic areas were studied. Specific adsorbed antisera were prepared in our laboratory and used in both tube and slide agglutination tests. Among the 177 cultures isolated during 1966 and 1967 in seven states and one Canadian province, the predominant serotype was 1.3 (or 1.3.6), represented by 85% of the cultures. Fifteen cultures were serotype 1.2.3.4.6. The 376 cultures isolated in the Grand Rapids area during the last 30 years showed a changing pattern from serotype 1.2.3 during the early years to the currently prevailing 1.3 (or 1.3.6). During the 2-year study period, seven cultures of B. parapertussis were isolated in Michigan, and seven were received from other states. One culture of B. bronchiseptica, recovered from a child in Boston, was sent to us. PMID- 4312924 TI - Utilization of electron spin resonance spectroscopy for observation of in vivo response to fungicides. AB - Electron spin resonance studies of the in vivo response to fungicides (chloranil and thiram) by Aspergillus niger of different ages are described. The spores possessed a natural free radical signal which grew rapidly upon application of chloranil. Thiram, on the other hand, produced weak changes in the free radical region but easily detectable changes at lower fields, indicating involvement of copper and iron. In addition, flow experiments are described in which the production and decay of the chloranil semiquinone radical produced in the reaction of solutions of chloranil with extracts of bakers' yeast were monitored, both in the absence and in the presence of several buffers and respiratory chain inhibitors. PMID- 4312925 TI - Antiviral and antitumor antibiotics. XX. Effects of rotenone, deguelin, and related compounds on animal and plant viruses. AB - Rotenoids and related compounds were investigated for their effects on animal and plant viruses. Of 35 compounds examined, rotenone, rotenone norketone, acetylrotenone, acetylrotenone norketone, deguelin, deguelic acid, dehydrodeguelin, and isotubanol norketone, all used at low concentrations, suppressed the growth of Newcastle disease and herpes simplex viruses as determined by the agar diffusion, plaque inhibition method. Most of the compounds likewise decreased the number of necrotic spots on tobacco mosaic virus-infected leaf discs. Only derrisic acid completely inhibited the local lesion formation at subphytotoxic concentrations. Correlation of antiviral activity with respiratory inhibition of these compounds is discussed. PMID- 4312926 TI - Correlations between virulence and other characters of Clostridium perfringens type A. AB - The correlation analysis which has already proved its value in ecology has not yet been applied to the determination of virulence indicators. Its application to a group of Clostridium perfringens type A strains has brought out some characters that may be considered as virulence indicators. This study suggests that the toxicity of the culture supernatant fluids for mice is significantly correlated with the virulence for mice and guinea pigs. A significant correlation was found between the virulence of the fluid cultures for mice or guinea pigs and the coagulation of milk, production of gas (in deep agar), hydrogen sulfide production, and fermentation of glucose, sucrose, maltose, and levulose. PMID- 4312927 TI - An amyloid forming nodular syringocystadenoma. PMID- 4312928 TI - [Hydrocyanic acid-free performance of Gattermann's aldehyde synthesis]. PMID- 4312930 TI - Some derivatives of polyvinylpyridine 1-oxides and their effect on the cytotoxicity of quartz in macrophage cultures. AB - 1. Poly(2-vinylpyridine 1-oxide) counteracts the pathogenic effects normally produced when quartz is injected into or inhaled by animals and the cytotoxic effects when quartz is added to macrophage cultures. The protective action of this polymer has been attributed variously to the formation of an adsorbed layer on the quartz particles, complex formation with monosilicic acid produced by the dissolution of quartz, and strengthening of the membranes or microstructures of the cells.2. Stereoregular forms of poly(2-vinylpyridine 1-oxide), some alkyl derivatives of poly(2-vinylpyridine 1-oxide), poly(3-vinylpyridine 1-oxide) and poly(4-vinylpyridine 1-oxide), a copolymer of 2-vinylpyridine 1-oxide and 2-n propenylpyridine 1-oxide, some poly(1-methyl-2-vinylpyridinium) quaternary salts, and poly(1-methoxy-2-vinylpyridinium iodide), which had previously been synthesized and studied with respect to their viscosities and interaction with silicic acid, were tested for their ability to counteract the cytotoxic effects of quartz in macrophage cultures. The tests were effected both by pretreating the quartz with polymers, and by pretreating the cells.3. Every polymer proved active in one or other of these conditions, but several were active in one test but inactive in the other. Some polymer quaternary salts, which do not contain the N oxide group, were found to be active. A remarkable difference in activity was found between the two stereoregular forms of poly(2-vinylpyridine 1-oxide). Pretreatment of the quartz with some of the polymers increased its cytotoxicity significantly.4. Most of the results could be interpreted on the hypothesis that the polymers form an adsorbed layer on the quartz surface, but it is difficult to apply this explanation to two polymers which are inactive when used to pretreat the macrophages but are active when adsorbed on quartz. PMID- 4312929 TI - Studies on cholinergic transmission in the medial geniculate nucleus. AB - 1. Studies were made on the effects of iontophoretically and intravenously administered cholinergic antagonists on the synaptic responses of medial geniculate (MG) neurones evoked by stimulation of the auditory cortex, inferior colliculus and mesencephalic reticular formation.2. Atropine specifically blocked a proportion of the excitatory responses evoked by stimulating the auditory cortex, inferior colliculus and reticular formation, although it was without effect on some of them.3. Neostigmine and eserine facilitated some excitatory synaptic responses evoked by inferior collicular stimulation.4. It is suggested that the feline MG nucleus receives excitatory cholinergic, as well as non cholinergic, pathways from the auditory cortex, inferior colliculus and lower brain stem. The cholinergic pathways from the auditory cortex may be either corticofugal fibres or recurrent axon collaterals of afferent projections from the MG nucleus to the cortex. Those from the lower brain stem are possibly the cholinesterase-containing fibres described by Shute & Lewis (1967). PMID- 4312932 TI - Germination of Macrophomina phaseoli sclerotia as effected by Pinus lambertiana root exudate. PMID- 4312934 TI - Combined effect of salt concentration and redox potential of the medium on the initiation of vegetative growth by Clostridium welchii. PMID- 4312931 TI - Vascular resistance in the perfused isolated rat tail. AB - 1. A constant flow perfusion system using the isolated rat tail has been developed to facilitate the study of resistance vessel behaviour and the action of vasoactive drugs.2. Baseline resistance remains stable for several hours and dose response curves to bolus injections of pressor agents are reproducible when dialysed bovine serum albumen is used in the perfusion medium to maintain osmotic pressure.3. Noradrenaline, adrenaline, serotonin, vasopressin, angiotensin II, high potassium concentrations and sympathetic nerve stimulation constricted the vascular bed.4. Angiotensin I, bradykinin, histamine, acetylcholine and isoprenaline did not alter vascular resistance under baseline conditions.5. Maximal sensitivity to noradrenaline occurred at 32 degrees to 34 degrees C. Below 30 degrees C, resting tone increased and the pressor effect of noradrenaline was prolonged.6. Low concentrations of (+/-)-propranolol in the perfusate enhanced adrenaline and noradrenaline vasoconstriction, high concentration of (+/-)-propranolol had a direct pressor effect and did not affect catecholamine responses.7. The preparation is a simple and relatively inexpensive adjunct to established methods of studying resistance vessel behaviour under varying experimental conditions. PMID- 4312936 TI - Anatomy of hereditary bovine syndactylism. II. Muscles, tendons, and ligaments. PMID- 4312933 TI - Gas chromatographic analysis of amines and other compounds produced by several species of Clostridium. PMID- 4312935 TI - Anatomy of hereditary bovine syndactylism. I. Osteology. PMID- 4312937 TI - Anatomy of hereditary bovine syndactylism. 3. Angiology. PMID- 4312938 TI - Anatomy of hereditary bovine syndactylism. IV. Neurology. PMID- 4312939 TI - Parotid fluid steroid responses to ACTH and dexamethasone in Cushing's syndrome. PMID- 4312941 TI - Light satellite-band DNA in mouse cells infected with polyoma virus. PMID- 4312940 TI - Genetic influence on the renin-angiotensin system. Evidence for a renin inhibitor in hypertension-prone rats. AB - TWO STRAINS OF RATS WITH OPPOSITE GENETIC PROPENSITY FOR HYPERTENSION WERE TESTED FOR: (a) the sensitivity to injections of angiotensin and renin, and (b) the influence of their plasma on the reaction velocity of renin and its substrate in vitro. Intact hypertension-prone (S) rats on low salt had higher sensitivity to angiotensin and a lower sensitivity to renin than hypertension-resistant (R) rats. High NaCl diet did not change the response of the R rats to these injections, but increased the response to renin and angiotensin in intact S rats. Bilateral nephrectomy caused increased response to renin and a decreased response to angiotensin in the S rats, so that both strains were equivalent after bilateral nephrectomy. In vitro, plasma from intact S rats inhibited the activity of hog renin. Plasma from R rats showed no inhibition. The inhibitor disappeared after bilateral nephrectomy. It was speculated that renin inhibitor may be involved in the development of hypertension by increasing sensitivity to angiotensin and other hypertensinogenic stimuli. PMID- 4312942 TI - [Molecular approach to the mechanism and treatment of herpesvirus keratitis]. PMID- 4312943 TI - [Enzyme histochemical studies on the regenerating rat cornea following heat coagulation of the epithelium]. PMID- 4312944 TI - Granular-cell myoblastoma of the oral cavity. PMID- 4312945 TI - [Practical value of endolymphatic radiotherapy. Isotopic lymphography]. PMID- 4312946 TI - [Comparative activity of 2 types of ribonucleic acids (RNA). A serologic reaction applied to the study of tumors]. PMID- 4312947 TI - Properties of mitochondria from hearts of cattle acclimatized to high altitude. PMID- 4312948 TI - Histochemical study of digitoxin-phosphate-oil cardiopathy. PMID- 4312950 TI - [Synthesis of a deproteinizing enzyme in various cell systems infected by variola group viruses]. PMID- 4312949 TI - [Virus infections and intrauterine pathology]. PMID- 4312951 TI - [Parallel studies of serum antibodies to para-influenza viruses in full-term and premature children]. PMID- 4312952 TI - [Experience in producing adenovirus preparations]. PMID- 4312953 TI - [The transforming activity of SV40 virus in tissue culture]. PMID- 4312954 TI - [The effect of histones from normal and infected cells on the reproduction of various DNA- and RNA-containing viruses]. PMID- 4312955 TI - [Obtaining antisera to para-influenza viruses type 4A and 4B]. PMID- 4312956 TI - [Effect of Bordetella pertussis on the lymphatic tissue of mice. V. Effect of Bordetella pertussis on the preparation of the lymphoreticular tissues for the secondary immunologic reaction]. PMID- 4312957 TI - [Investigations on oncogenic transformation, induction of DNA-synthesis and t antigen formation by UV-irradiated simian virus (SV-) 40]. PMID- 4312958 TI - [Effect of agar and agar extracts on the Sendai virus. I. Inhibition of the hemolytic activity of Sendai virus by agar and aqueous agar extract]. PMID- 4312960 TI - [Cytological studies on the diagnosis and etiology of erythroleukemia]. PMID- 4312959 TI - Inter-relations between iron stores, general factors and intestinal iron absorption. PMID- 4312961 TI - Periodic acid-Schiff reaction in human basophilic leucocytes. PMID- 4312962 TI - Linear systems analysis of the Limulus retina. PMID- 4312963 TI - Endocrinology and the systems paradigm. PMID- 4312964 TI - [Interferon-inducing capacity of double-stranded RNA. II. Studies on Mengo virus replicatative intermediate]. PMID- 4312965 TI - Nonparticipation of transfer RNA in the biosynthesis of polymyxin B. PMID- 4312966 TI - Chromatographic differences between lysyl-tRNA's from avian tumor virus BAI strain A and virus transformed cells. PMID- 4312967 TI - Alteration in the ionic properties of aminoacyltransferase II from rat liver by NAD+ and diphtheria toxin. PMID- 4312968 TI - DNA polymerase activities in Tradescantia paludosa pollen grain nuclei. PMID- 4312969 TI - Intestinal parasites. PMID- 4312970 TI - ["Good and bad luck" of the 1st African experiment of leprosy surgery in a general hospital]. PMID- 4312972 TI - Granular cell myoblastoma. PMID- 4312971 TI - Enzymes of entamoeba histolytica. AB - In spite of extensive studies of the pathogenic activities of Entamoeba histolytica upon animal hosts by many investigators, the factors that govern the pathogenesis of the parasite are still largely unknown. Attempts have been made to determine the factors concerned in the pathogenicity of certain strains of E. histolytica from the aspect of parasite itself and from the point of view of its interaction with the host. The enzyme content of the trophozoites of the amoebae examined has been studied in detail, both in the living organism and in its extracts. The total patterns of proteolytic enzymes and of certain other enzymes were determined to establish whether it was possible to define the invasiveness of the various strains of E. histolytica already established as pathogenic by other workers or in our laboratories. It was found impossible to distinguish clearly between the so-called "pathogenic" and "non-pathogenic" strains of E. histolytica by such means. PMID- 4312973 TI - Current concepts in the detection and treatment of the earliest of the early breast cancers. PMID- 4312974 TI - [Monocytes in infiltrate of psoriatic lesions]. PMID- 4312976 TI - Biosynthesis of labeled mouse tumor ACTH. PMID- 4312975 TI - Effect of vitamin A deficiency on 3beta-hydroxysteroid dehydrogenase activity and corticosterone in the rat adrenal. PMID- 4312977 TI - Persistence of label in rat offspring after maternal administration of a 14C labeled inhibitor of 3beta-hydroxysteroid dehydrogenase. PMID- 4312978 TI - Role of the pituitary in controlling aldosterone production in sodium-depleted rats. PMID- 4312979 TI - Effect of pituitary and ACTH on the maintenance of basal tyrosine hydroxylase activity in the rat adrenal gland. PMID- 4312980 TI - Dibutyryl cyclic AMP, vitamin D and intestinal permeability to calcium. PMID- 4312982 TI - Demonstration of membrane-linked iodoprotein in hepatic microsomes following metabolism of the thyroid hormones. PMID- 4312983 TI - Role of lecithin in the mechanism of TSH action. PMID- 4312981 TI - Requirement of Ca++ and Mg++ ions for the in vitro release of follicle stimulating hormone from rat pituitary glands and in its subsequent biosynthesis. PMID- 4312984 TI - ACTH release evoked by electrical stimulation of brain stem and limbic system sites in the cat: The absence of ACTH release upon infundibular area stimulation. PMID- 4312986 TI - ACTH, Corticosteroids and inhibition of protein synthesis. PMID- 4312985 TI - Proteolysis in thyroid slices: Effects of TSH, dibutyryl cyclic 3', 5'-AMP and prostaglandin E. PMID- 4312987 TI - Inhibition by thyrocalcitonin of the mitogenic actions of parathyroid hormone and cyclic adenosine=3',5'-monophosphate on rat thymocytes. PMID- 4312988 TI - Histochemical study of isolated intratubular cells of the rat testis. I. Hydrolases and phosphorylase. PMID- 4312990 TI - An improved procedure for separation of catecholamines from plasma. PMID- 4312989 TI - Histochemical study of isolated intratubular cells of the rat testis. II. Oxidases and dehydrogenases. PMID- 4312991 TI - Dense core vesiculated axons in the renal portal valve of the domestic fowl. PMID- 4312992 TI - Stimulation of corticosteroid secretion in man with a triazine derivative. PMID- 4312993 TI - Comparison of purified human and procine ACTH in man. PMID- 4312994 TI - Herpes simplex virus infection in infants: a spectrum of disease. PMID- 4312995 TI - 5-iodo-2'-deoxyuridine in neonatal herpesvirus hominis encephalitis. PMID- 4312996 TI - Picrotoxin antagonism of the inhibition of interneurons by glycine. PMID- 4312997 TI - Species difference in the structure of urinary 2-hydroxyestrone glucuronide. PMID- 4312998 TI - A study of the effect of ionizing radiation on resistance, germination, and toxin synthesis of Clostridium botulinum spores, types A, B, and E. COO-1095-3. PMID- 4312999 TI - A simplified determination of urinary testosterone utilizing column and gas liquid chromatography. SAM-TR-68-117. PMID- 4313000 TI - [Experience of the infectious disease consultation department concerning the dispensarization of patients with infectious hepatitis]. PMID- 4313002 TI - [Objectivation of lumbar ischialgia by means of galvanometry and rheography]. PMID- 4313001 TI - [Several characteristics of peripheral nervous system diseases in workers from a sulfur mining and chemical production concern]. PMID- 4313003 TI - [Function of the hypophysis in peptic ulcers]. PMID- 4313004 TI - Oxygen, uptake, transport, and tissue utilization. PMID- 4313005 TI - Tumors of the marmoset produced by Rous sarcoma virus. PMID- 4313006 TI - Structural and regulatory aspects of enzymes in chemotherapy. PMID- 4313007 TI - Effect of p-fluorophenylalanine on the replication of herpes simplex virus. PMID- 4313008 TI - Enzymes of gluconeogenesis in tumor-bearing rats. PMID- 4313009 TI - Effects of ACTH, metopirone and dexamethasone on maternal urinary steroid excretion in late pregnancy. PMID- 4313010 TI - [Determination of 2-deoxysugars and deoxyribonucleic acid]. PMID- 4313011 TI - [X-ray contrast demonstration of the thoracic duct with enterally resorbed iodized oil emulsions in the cat]. PMID- 4313012 TI - [Use of glutaraldehyde in the detection of esterases in seminal epithelium]. PMID- 4313013 TI - [Sleep and hypothalamic gonadotropin regulation in the female rabbit]. PMID- 4313014 TI - [2 rare cases of benign renal muscular neoplasms (benign myoblastoma and benign lipoblastomyoma)]. PMID- 4313015 TI - Correlation between poliomyelitisvirus-reproduction-cycle, chromosomal alterations and lysosomal enzymes. PMID- 4313016 TI - Purification of Sendai virus. PMID- 4313017 TI - Studies on the pathogenesis of monkey pox. II. Dose-response and virus dispersion. PMID- 4313018 TI - Studies on the pathogenesis of monkey pox. 3. Histopathological lesions and sites of immunofluorescence. PMID- 4313019 TI - Hemagglutinin of vesicular stomatitis virus. PMID- 4313020 TI - [Properties of the vesicular stomatitis virus adapted to Drosophila]. PMID- 4313021 TI - A study of the interference phenomenon in vesicular stomatitis virus replication. PMID- 4313022 TI - Homotypic and heterotypic interference among picornavirus ribonucleic acids. PMID- 4313023 TI - Chromatographic analysis of mixed populations of poliovirus. PMID- 4313025 TI - Differential sensitivity to gliotoxin of virulent and attenuated poliovirus strains and its possible use as a genetic marker. PMID- 4313024 TI - Antiviral action of gliotoxin. PMID- 4313026 TI - An interferon-like inhibitor of foot-and-mouth disease virus induced by phytohemagglutinin in swine leukocyte cultures. PMID- 4313027 TI - [Giant cell formation and virus-specific antigens of herpesvirus hominis: information flow from the parental DNA]. PMID- 4313028 TI - Poliovirus inhibition of the phytohemagglutinin response in human lymphocytes. PMID- 4313029 TI - [Reo-3 infection in white mice]. PMID- 4313030 TI - [Fluorescence serology studies on the effects of antiviral agents on virus replication. I. The action of beta-2-DL-thienyl alanine on the replication of Mengo virus]. PMID- 4313032 TI - [Induction of interferon in the brain of baby mice by viruses of the tick-borne encephalitis (TBE) complex]. PMID- 4313031 TI - Enhancement and neutralization of pyrogenicity of influenza viruses by various biologically active substances. PMID- 4313033 TI - [UV inactivation of herpes simplex virus from cell cultures treated with 5 bromodeoxyuridine and 5-iododeoxyuridine]. PMID- 4313034 TI - [Infectious herpesvirus hominis containing bromodeoxyuridine. Determination of the density and of the sedimentation constant in CsCl-H2O density gradient]. PMID- 4313035 TI - The development of neutralizing antibodies in guinea pigs following immunization with human cytomegalovirus. PMID- 4313036 TI - Effect of temperature on synthesis of T and V antigens of papovavirus SV 40 and induction of thymidine kinase. PMID- 4313037 TI - Interaction of non-steroidal antiinflammatory agents with corticosterone binding to plasma proteins in the rat. PMID- 4313038 TI - [Carcinogenic effect of 1,2-dimethylhydrazine in gold hamster]. PMID- 4313039 TI - [Renin-angiotensin-aldosterone system from the clinical viewpoint]. PMID- 4313040 TI - [Neuraminidase as a pathogenic factor in gas gangrene infections with Clostridium perfringens]. PMID- 4313041 TI - Retardation of protein synthesis in rat tumours on inhibiting histamine formation. PMID- 4313042 TI - Purines and cortisone in lipid mobilization. PMID- 4313043 TI - An in vitro system for studying mucus secretion and other physiological activities in human intestinal mucosa. PMID- 4313045 TI - Dissociation of RNA-histone complexes by DNA. PMID- 4313044 TI - The properties of neuraminidase-treated crystalline ceruloplasmin. PMID- 4313046 TI - Effect of sodium fluoride on the epinephrine response of liver and hepatoma adenyl cyclase. PMID- 4313048 TI - Intratypic differentiation of poliovirus strains of type I from pre- and post vaccination groups. PMID- 4313047 TI - Collagen substrate films for localizing collagenolytic activity histologically. PMID- 4313049 TI - Enteroviruses from cases of encephalitis in Pondicherry. PMID- 4313050 TI - Observation on the intraluminal fluid obtained from rat uteri with an intrauterine device in one horn. PMID- 4313051 TI - Effect of nitrate, fumarate, and oxygen on the formation of the membrane-bound electron transport system of Haemophilus parainfluenzae. AB - The composition of the membrane-bound electron transport system of Haemophilus parainfluenzae underwent modification in response to the terminal electron acceptor in the growth medium. H. parainfluenzae was able to grow with O(2), nitrate, fumarate, pyruvate, and substrate amounts of nicotinamide adenine dinucleotide (NAD) as electron acceptors. When O(2) served as the electron acceptor and its concentration was lowered below 20 mum, the bacteria formed more cytochromes b, c, a(1), a(2), and o than were present in the cells grown at 150 to 200 mum O(2). Nitrate and nitrite reductase activities also appeared during growth at the low O(2) concentrations in the absence of added nitrate. Cytochrome levels in cells grown anaerobically with fumarate, pyruvate, or NAD as terminal acceptors were similar to those formed in cells grown at low O(2) concentrations. Cells grown with nitrate had higher levels of cytochromes c, b, and o, and of nitrate and nitrite reductases, than did cells grown with the other acceptors. The formation of cytochrome oxidase a(2) was repressed by the presence of nitrate in the growth medium. The critical O(2) concentration (the O(2) concentration at which the rate of O(2) uptake becomes demonstrably dependent on the O(2) concentration) was about 100 mum in cells grown with nitrate and about 15 mum in cells grown with the other acceptors. A mutant of H. parainfluenzae was found to make about 10% as much cytochrome c as the wild type, and its formation of cytochrome a(2) was not repressed by nitrate. The critical O(2) concentration of the mutant was high when it was grown with nitrate, suggesting that the high levels of cytochrome c and the absence of cytochrome a(2) from the wild type are not responsible for the high critical O(2) concentration. The modifications of the respiratory system induced by changing the terminal electron acceptor were inhibited by the presence of chloramphenicol, which suggests that protein synthesis is involved. PMID- 4313052 TI - In vivo suppression of coding associated with bacteriophage-induced S adenosylmethionine hydrolase. AB - The methylation of ribosomal and transfer ribonucleic acid (RNA) synthesized after the induction of a hydrolase for S-adenosylmethionine by phage T3 infection is reducible to 50% of the methylation of RNA in uninfected cells. Hypomethylated ribosomal RNA is found in 70S particles that dissociate in 100 mum Mg(++) to yield only 30S and 50S subunits. By this criterion, the omitted methyl groups apparently are not required for ribosomal maturation or stability. The rate of production of alkaline phosphatase in a phosphatase amber mutant was examined after phage infection in the presence and in the absence of streptomycin to determine the effect on the translation process consequent to S-adenosyl-l methionine (SAM) hydrolase induction. Significant increases in the rates of phosphatase production were found when ultraviolet-inactivated T3 or streptomycin was added. The effects were cumulative when the cells were treated with both bacteriophage and the drug. Ultraviolet-inactivated T7, a phage closely related to T3 but which does not produce the SAM hydrolase, did not enhance the rate of alkaline phosphatase production. We suggest that the production of SAM hydrolase affects the stability of the translation process by the observed hypomethylation or by mechanisms concerning polyamine metabolism. PMID- 4313053 TI - Regulation of enzymes involved in the conversion of tryptophan to nicotinamide adenine dinucleotide in a colorless strain of Xanthomonas pruni. AB - A colorless strain of Xanthomonas pruni was isolated which is capable of converting tryptophan to nicotinamide adenine dinucleotide (NAD). The enzymes responsible for the conversion of tryptophan to quinolinic acid were shown to be present. Nicotinic acid-requiring mutants were isolated, and it was found that the growth of these mutants can be supported by various intermediates on the pathway from tryptophan to NAD. The first three enzymes on this pathway are induced coordinately by l-tryptophan. Gratuitous inducers of these enzymes include d-tryptophan, alpha-methyl-dl-tryptophan, and 4-methyl-dl-tryptophan; formyl-l-kynurenine and l-kynurenine were not effective as inducers. These data suggest that at least the first three enzymes in the pathway from tryptophan to NAD are under common regulatory control. PMID- 4313054 TI - [Effect of prolonged hydrochlorothiazide administration on the plasma renin activity and aldosterone excretion rate in normal persons]. PMID- 4313055 TI - [Neurological disorders in chronic ethylism in the province of Belluno]. PMID- 4313056 TI - Neuropathy: mono- or poly-? PMID- 4313058 TI - [Traumatic neuritis of the peroneal nerve after correction of tibia vara]. PMID- 4313057 TI - [Eye complications during use of various medicinal substances with general effects (review of the literature)]. PMID- 4313059 TI - [Leukemia in infancy]. PMID- 4313060 TI - [Drepanocytosis]. PMID- 4313061 TI - [Intercoronary anastomosis. Functional value and pathological significance]. PMID- 4313063 TI - [Muscular tuberculosis. Apropos of a case]. PMID- 4313062 TI - [Clinical and biological study of a form of beriberi specific to Vietnam: beriberi after childbirth]. PMID- 4313064 TI - [1st case of human brucellosis due to "Brucella suis" observed in France]. PMID- 4313065 TI - [The specificity of the indirect plaque technic. II. The developmental capacity of various types of antisera against 7S and 19S immunoglobulins by means of the indirect antibody-plaque technic]. PMID- 4313067 TI - [Electromyographic changes in occupational diseases of the peripheral nerves]. PMID- 4313066 TI - [Clinico-anatomic parallels in Itsenko-Cushing disease]. PMID- 4313068 TI - Antibiotic acquistions in a 387-bed general hospital during 1960, 1965, 1967 and 1968. PMID- 4313069 TI - Reidel's lobe of the liver. PMID- 4313070 TI - Visual sensitivity. PMID- 4313071 TI - The isolation and characterization of a hydroxamic acid (aerobactin) formed by Aerobacter aerogenes 62-I. PMID- 4313072 TI - Interaction of N-methyl-N'-nitro-N-nitrosoguanidine with ascites hepatoma cells in vitro. PMID- 4313073 TI - Mode of thyroxine action in the activation of glycogen synthetase of Rana catesbeiana tadpoles. PMID- 4313074 TI - Adrenal corticosteroid involvement in the control of liver glycogen phosphorylase activity. PMID- 4313075 TI - Adrenal corticosteroid involvement in the control of phosphorylase in muscle. PMID- 4313076 TI - Equilibrium kinetic study of enzyme modifier action. PMID- 4313077 TI - Enzyme-substrate kinetics associated with transient state conditions in single living cells. PMID- 4313078 TI - An ATP-incorporating enzyme from rat brain. I. Solubilization and requirements. PMID- 4313079 TI - Enzymatic dephosphorylation 3'-phosphoadenosine 5'-phoaphosulfate to adenosine 5' phosphosulfate in sheep brain. PMID- 4313080 TI - Liver microsomal inorganic pyrophosphate-glucose phosphotransferase and glucose-6 phosphatase. Effects of diabetes and insulin administration in kinetic parameters. PMID- 4313081 TI - The effect of collagenase preparations contaminated with phospholipase C activity on adipose tissue lecithin. PMID- 4313082 TI - The role of hydrocyanic acid in nutrition. PMID- 4313083 TI - Neurological complications of systemic diseases. I. PMID- 4313084 TI - [Lymphography in the diagnosis of local metastases of breast cancer]. PMID- 4313086 TI - Special service: friendly visitor. PMID- 4313085 TI - Lymphocyte transformation in young people. PMID- 4313087 TI - The distrubution of iron in iron-deficient toxin-synthesizing and in excess-iron non-toxin-synthesizing Corynebacterium diphtheriae. PMID- 4313088 TI - [Function of diencephalon-hypophyseal system: 1969 Japan Medical Association prize winning thesis]. PMID- 4313089 TI - Syndactylism with deformity of the pectoralis muscle. Poland's syndrome. PMID- 4313090 TI - [Complications of myelography with methiodal]. PMID- 4313091 TI - [Histoenzymology of the bone marrow in relation to the principal metabolic pathways]. PMID- 4313092 TI - [Cytochemical study of lactic acid in leukemia cells]. PMID- 4313093 TI - [Cytochemical studies and chromosomes in non-hemopathic diseases]. PMID- 4313094 TI - Clinical neurology. PMID- 4313095 TI - Radiology of the skull and central nervous system. PMID- 4313096 TI - Psychosomatic medicine. PMID- 4313097 TI - [Spleno-renal venous anastomoses associated with hepatic cirrhosis]. PMID- 4313098 TI - [Diet therapy in gout]. PMID- 4313099 TI - [Attempt at an anatomo-pathological correlation of coronary atherosclerosis and its implications]. PMID- 4313100 TI - [The true portrait of Antonmarchi, last physician of the emperior]. PMID- 4313101 TI - [Cagliostro, magician or impostor?]. PMID- 4313102 TI - [Kidney tumors in children]. PMID- 4313103 TI - Isolation of Mycoplasma hominis, T-strains, and cytomegalovirus from the cervix of pregnant women. PMID- 4313104 TI - The use of hyperbaric oxygen in the treatment of clostridial septicemia complicating septic abortion. Report of a case. PMID- 4313105 TI - Inhibition of toad bladder responses to neurohypophysial hormones by (4-leucine) oxytocin. PMID- 4313106 TI - Pituitary-adrenal alterations and fear responding. PMID- 4313107 TI - Absence of renin in kidneys of elasmobranchs and cyclostomes. PMID- 4313108 TI - Probenecid inhibition of arginine vasotocin in snakes, frogs, and on frog bladders in vitro. PMID- 4313109 TI - Effect of cord factor on carbohydrate metabolism in mice. PMID- 4313110 TI - Cavitary bronchiolar carcinoma. PMID- 4313111 TI - Streptomycin-induced neuromuscular fatigue in myasthenia gravis. PMID- 4313112 TI - The influence of bradykinin and angiotensin on the muscularis of the digestive tract in experimental animals. PMID- 4313113 TI - Glomus tympanicum tumor in an otosclerotic ear. PMID- 4313114 TI - Transport of reduced nicotinamide-adenine dinucleotide into mitochondria of rat white adipose tissue. AB - Mitochondria from rat white adipose tissue were prepared, exhibiting good respiratory control and P/O ratios. They would not oxidize NADH unless NNN'N' tetramethyl-p-phenylenediamine was added as a carrier of reducing equivalents. These mitochondria were found to oxidize neither l-glycerol 3-phosphate nor l glutamate plus l-malate at significant rates. The activity of aspartate aminotransferase in these mitochondria was found to be low compared with that found in rat liver mitochondria. As a consequence of this, the adipose-tissue mitochondria exhibited very low rates of cytoplasmic NADH oxidation in a reconstituted Borst (1962) cycle compared with liver mitochondria. PMID- 4313115 TI - The role of the cytoplasmic redox potential in the control of fatty acid synthesis from glucose, pyruvate and lactate in white adipose tissue. AB - The metabolism of lactate, pyruvate and glucose was studied in epididymal adipose tissue of starved, normally fed and starved-re-fed rats. Lactate conversion into fatty acid occurred at an appreciable rate only in the adipocyte of starved-re fed animals. NNN'N'-Tetramethyl-p-phenylenediamine, an agent that transports reducing power from the cytoplasm to the mitochondria, caused large increments of fatty acid synthesis from lactate and a smaller one from glucose but a decrease in that from pyruvate. Glucose (1.0mm) increased fatty acid synthesis from lactate 4.3-fold but only 1.67-fold from pyruvate in adipocytes from normally fed animals. 2-Deoxyglucose decreased fatty acid synthesis from lactate to a greater degree (threefold) compared to that from pyruvate in adipocytes from starved-re fed animals. l-Glycerol 3-phosphate contents were approximately equal in epididymal fat-pads, incubated in the presence of lactate or pyruvate, from normally fed animals, whereas the addition of 1mm-glucose resulted in a tenfold increase in l-glycerol 3-phosphate content only in the presence of lactate. The l glycerol 3-phosphate content was tenfold higher in adipose tissue from starved-re fed animals incubated in the presence of lactate than in the presence of pyruvate. 2-Deoxyglucose caused these values to be slightly lowered in the presence of lactate. We suggest that lactate metabolism is limited by the rate of NADH removal from the cytoplasm. In the starved-re-fed state, this occurs by reduction of dihydroxyacetone phosphate formed from glycogen to produce l glycerol 3-phosphate, thus permitting lactate conversion into fatty acid. When glucose is the substrate, and rates of transport are not limiting, the rate of removal of cytoplasmic NADH limits glucose conversion into fatty acid. PMID- 4313116 TI - Ubisemiquinone in membranes from Escherichia coli. PMID- 4313117 TI - Effect of mercuric chloride on the arterial blood pressure of dogs. PMID- 4313118 TI - On the nomenclature of asymmetrically substituted myoinositol derivatives with particular reference to phosphatidylinositols. PMID- 4313119 TI - Silicic acid chromatography of organic acids in blood cells and biological fluids. PMID- 4313120 TI - Enzyme activity determinations in bone and cartilage. PMID- 4313121 TI - Some biochemical characteristics of rodent and human mammary carcinomas. PMID- 4313122 TI - [Effects of carbohydrate depletion and repletion on the activity of some enzymes in liver and epididymal adipose tissue of Wistar H rats fed a high fat diet]. PMID- 4313123 TI - [Effects of insulin on the activity of enzymes in liver and epididymal adipose tissue of Wistar H rats in a state of nutritional obesity]. PMID- 4313124 TI - Disaccharidase content in the small-intestinal mucosa of normal mouse and of mouse with viral MHV-3 hepatitis. PMID- 4313125 TI - Metabolism of ethanol and fructose in the perfused rat liver. PMID- 4313126 TI - Local inhibition of mastocalcergy by calciphylactic challengers. PMID- 4313127 TI - Clinical significance of rheumatoid vasculitis and the incidence of digital vascular lesions. PMID- 4313128 TI - Bacteriology of urinary tract infections. I. A quantitative bacteriologic study with antibiotic sensitivity of the strains isolated. PMID- 4313129 TI - [2 cases of stomach cancer with systemic metastasis]. PMID- 4313130 TI - Hexuronic acid dehydrogenase of Agrobacterium tumefaciens. AB - Growth of Agrobacterium tumefaciens on d-glucuronic acid (GlcUA) or d galacturonic acid (GalUA) induces formation of hexuronic acid dehydrogenase [d aldohexuronic acid: nicotinamide adenine dinucleotide (NAD) oxidoreductase]. The dehydrogenase, which irreversibly converts GlcUA or GalUA to the corresponding hexaric acid with the concomitant reduction of NAD, but not of nicotinamide adenine dinucleotide phosphate was purified 60-fold by MnCl(2) treatment, (NH(4))(2)SO(4) fractionation, chromatography on diethylaminoethyl Sephadex and negative adsorption with Ca(3)(PO(4))(2) gel. The pH optimum is 8.0. Other uronic acids, aldohexoses, aldopentoses, and polyols, are not substrates. Reduced nicotinamide adenine dinucleotide is an inhibitor strictly competitive with NAD. Kinetic data indicate that the dehydrogenase induced by growth on GlcUA may not be identical with that induced by growth on GalUA. PMID- 4313131 TI - Mode of nicotinamide adenine dinucleotide utilization by Escherichia coli. AB - Exogenous nicotinamide adenine dinucleotide is not utilized per se by Escherichia coli, but is converted to nicotinamide and thence to nicotinamide adenine dinucleotide via nicotinate. PMID- 4313132 TI - Role of divalent cations in the action of polymyxin B and EDTA on Pseudomonas aeruginosa. PMID- 4313133 TI - [2 cases of primary multiple cancer found in the course of postoperative irradiation for breast cancer]. PMID- 4313134 TI - Persistent jaundice. Resume of case. PMID- 4313135 TI - [Remote results of clinical observation of the oncolytic action of adenoviruses on cervix cancer]. PMID- 4313136 TI - [A case of arrhenoblastoma of the ovary (arrhenoblastoma trabeculare ovarii)]. PMID- 4313137 TI - [Ultrastructure of adenoid cystic cancer of the breast]. PMID- 4313138 TI - Association of maternal genital herpetic infection with spontaneous abortion. PMID- 4313139 TI - [Anatomo-clinical findings on the so-called sinus tarsi syndrome]. PMID- 4313140 TI - [Surgical problems in the therapy of jugular ganglion neoplasms]. PMID- 4313142 TI - The effect of light and darkness on lactic acid content of the pineal gland. PMID- 4313141 TI - Studies on the mitochondrial electron transport system in Aspergillus. PMID- 4313143 TI - Radiation inhibition of peritoneal adhesions: an experimental study. PMID- 4313144 TI - Isolation of viruses from primary dog cell cultures and the occurrence of viral antibody in donor animals. PMID- 4313145 TI - A trypsin technic for the preparation of isolated rat anterior pituitary cells. PMID- 4313147 TI - Species source of complement in viral-immune and other cytolytic reactions. PMID- 4313146 TI - Heterocyclic thiosemicarbazones: correlation between structure, inhibition of ribonucleotide reductase, and inhibition of DNA viruses. PMID- 4313148 TI - Method for chromosome preparation from mouse peripheral lymphocytes. PMID- 4313149 TI - Immunogenicity of rhinoviruses. PMID- 4313150 TI - A generalized infection of newborn hamsters with type 2 adenovirus. PMID- 4313151 TI - Alpha-glycerophosphate dehydrogenase inhibition in rat heart and adipose tissue. PMID- 4313152 TI - Inhibition of poliovirus by effect of a methylthiopyrimidine derivative. PMID- 4313153 TI - Comparison of antigens from human and chimpanzee herpes-type virus-infected hemic cell lines. PMID- 4313154 TI - Studies of hamster-specific oncogenic virus derived from hamster tumors induced by Kirsten murine sarcoma virus. PMID- 4313155 TI - Attempts at isolation of lymphocytosis-producing factor from supernatant fluids of Bordetella pertussis cultures. PMID- 4313156 TI - Sialographic study of diseases of the major salivary glands. PMID- 4313157 TI - Feline viruses: isolation, characterization, and pathogenicity of a feline reovirus. PMID- 4313158 TI - Pathogenesis of canine herpesvirus encephalitis. PMID- 4313159 TI - Biological and physicochemical properties of ground squirrel cytomegalovirus. PMID- 4313160 TI - Inhibition of foot-and-mouth disease virus by normal bovine serum. PMID- 4313161 TI - Aqueous humor penetration of several antibiotics in the dog. PMID- 4313162 TI - Hereditary methemoglobinemia, toxic methemoglobinemia and the reduction of methemoglobin. PMID- 4313163 TI - Clinical aspects of drug reactions in hereditary hepatic porphyria. PMID- 4313164 TI - Atypical human liver alcohol dehydrogenase. PMID- 4313165 TI - Effects of l-(2-nitro-l-imidazolyl)-3-methoxy-2-propanol and 2-methyl-5 nitroimidazole-l-ethanol against anaerobic and aerobic bacteria and protozoa. AB - 1-(2-Nitro-1-imidazolyl)-3-methoxy-2-propanol (RO 7-0582) and 2-methyl-5 nitroimidazole-1-ethanol (Metronidazole), substances known to be potent trichomonacides, were shown to inhibit obligate anaerobic bacteria in vitro but were essentially without effect at the doses tested against bacteria capable of growing aerobically. A similar effect was noted in vivo in that both substances exhibited good chemotherapeutic activity against infections produced by three species of anaerobic protozoa but were essentially inactive at the doses tested against three species of aerobic protozoa. PMID- 4313166 TI - Interferon production by human leukocytes in vitro: some biological characteristics. AB - Interferon was optimally produced in human peripheral leukocyte cultures incubated for approximately 19 hr in the presence of Sendai virus at a multiplicity of 10 to 50 EID(50)/cell. For determining whether deoxyribonucleic acid (DNA) synthesis per se was essential for interferon production, 1-beta-D arabinofuranosylcytosine (Ara-C), a potent DNA inhibitor was studied for its effect on interferon production in leukocytic and bone marrow cell cultures. These cells showed no impaired capacity to produce interferon when treated with 15 mug of Ara-C per ml. Interferon yields were also determined in leukocyte cultures treated with actinomycin D (0.1 mug/ml) and puromycin (10 mug/ml) at various times before and after virus inoculation. The data suggested that sequential transcriptive and translational events were required for the de novo synthesis of interferon by the infected leukocytes, in a manner similar to other known virus-induced interferon-producing systems. The synthesis of macromolecules and the effects of antimetabolites in leukocytes and bone marrow cell cultures were followed by measuring the incorporation of thymidine-2-(14)C, uridine-5 (3)H, and L-phenylalanine-1-(14)C. The effect of 0.1 mug of actinomycin per ml on the capacity of leukemic leukocytes to produce interferon was also studied. Preliminary data showed that, in contrast to nonleukemic leukocytes, interferon production by leukemic leukocytes was only partially inhibited by actinomycin. PMID- 4313167 TI - Effect of mixed cultures on antibiotic susceptibility testing. AB - Careful studies of the antibiotic susceptibilities of mixtures of bacteria likely to be encountered in clinical cultures have shown that the results obtained are completely unreliable. Mixtures of resistant and sensitive species appeared either as "resistant" or "sensitive" depending upon the organisms and the drug. A number of sensitive species gave reactions interpreted as resistant when tested in combination. Since reactions of bacterial mixtures are completely unpredictable, the authors emphasize that antibiotic susceptibility testing be limited to pure cultures. PMID- 4313168 TI - Growth, sporulation, and germination of Clostridium perfringens in media of controlled water activity. AB - Requirements in terms of water activity (a(w)) for the growth, sporulation, and germination of Clostridium perfringens were determined. Strain A48 was used in all phases, and in addition either NCTC 8239 or NCTC 8797 was used for growth, sporulation, and germination studies. The desired a(w) of the test media was obtained by the addition of one of three solutes: glycerol, sucrose, or sodium chloride. The freezing point depression method was used to determine the a(w). The basal medium for growth and germination was Fluid Thioglycollate Medium. It had an a(w) of 0.995 and produced maximum growth and fastest growth rate among the six levels of a(w) tested. The lowest a(w) supporting growth and germination of C. perfringens was between 0.97 and 0.95 in the test media made with sucrose or sodium chloride and 0.93 or below in the test media adjusted with glycerol. Spore production by C. perfringens in Ellner's or modified medium required a higher a(w) than growth. PMID- 4313169 TI - Production of interferon in serum-free human leukocyte suspensions. AB - The recovery of interferon from Sendai-infected suspensions of purified human leukocytes is dependent on the serum concentration in the incubation medium. Very little interferon is obtained from serum-free suspensions. The data reported demonstrate that the critical macromolecular, age-independent, and species unspecific serum principle can be omitted from the suspensions if the medium is supplemented with a combination of crystalline serum albumin and high concentrations of any one of five studied dipolar ionic buffers [N,N-bis(2 hydroxyethyl) glycine (Bicine), N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid (HEPES), 2-(N-morpholino)ethanesulfonic acid (MES), N tris(hydroxymethyl)methyl-2-amino-ethanesulfonic acid (TES), and N tris(hydroxymethyl)methylglycine (Tricine)]. The optimal combination [TES (1.0%, w/v) and bovine serum albumin (0.8%, w/v)] allows the production of potent preparations of serum-free human interferon. PMID- 4313170 TI - Effectiveness of acetic acid, betadine, amphyll, polymyxin B, colistin, and gentamicin against Pseudomonas aeruginosa. AB - The in vitro effectiveness of three germicides and three chemotherapeutic drugs against hospital-isolated strains of Pseudomonas aeruginosa was determined. Solutions of 1% acetic acid, 0.5% Amphyll, and 0.1% Betadine were bactericidal for six strains tested within 15 min at room temperature. Over a 3-year period at the Albany Medical Center Hospital, the percentages of strains of P. aeruginosa susceptible to polymyxin B, colistin, and gentamicin did not increase. During this 3-year period, polymyxin B and colistin were administered at the hospital but gentamicin was not. PMID- 4313172 TI - Rapid plaque assay for encephalomyocarditis virus. AB - A liquid overlay plaquing technique is described which offers a rapid and simple plaque assay system for small plaque variants of encephalomyocarditis virus. PMID- 4313171 TI - Effect of prehumidification on sampling of selected airborne viruses. AB - Studies were undertaken to determine if a prewetting device (humidifier bulb) used in combination with an all glass impinger (AGI-30) would increase the recovery of airborne mengovirus-37A, vesicular stomatitis virus (VSV), and the S 13 coliphage. Suspensions of T3 coliphage with mengovirus-37A, VSV, or S-13 were aerosolized and collected by using the AGI-30-humidifier bulb combination to sample the aerosols before and after shifts in relative humidities (RH). These studies revealed the following. (i) At low RH values there was a 3 to 4 log increase in recovery of airborne T3 phage; (ii) concomitantly, the recovery of mengovirus-37A and VSV decreased; and (iii) only at the mid-range RH values was the recovery of S-13 enhanced. The prehumidification technique significantly increased the recovery of airborne T3 phage but decreased the recovery of the two animal viruses tested. PMID- 4313173 TI - Quantitation of tail lesions in vaccinia-infected mice. AB - When mice were infected with vaccinia virus via the tail vein, the number of lesions was influenced by the injection site. A site 3 cm from the base of the tail is of greatest practical value. PMID- 4313174 TI - [Hyperplasiogenic multiform glioblastoma and dedifferentiated glioma]. PMID- 4313175 TI - [Histochemical characteristics of ascorbic acid in nervous system tumors]. PMID- 4313176 TI - [Possibilities of postmortem histochemical study of enzyme activity in tissues]. PMID- 4313177 TI - The isolation and characterization of the plasma membrane from chick embryo fibroblasts. PMID- 4313178 TI - The control of fatty acid composition in glycerolipids of the endoplasmic reticulum. PMID- 4313179 TI - [Clinical evaluation of epithelial proliferation in benign breast neoplasms and mastopathies]. PMID- 4313180 TI - [Clinical experience with biliary tract carcinoma]. PMID- 4313181 TI - [Dynamics of corticosteroids among pregnant women]. PMID- 4313182 TI - Blood sugar, serum insulin and free fatty acid interrelationships during intravenous tolbutamide testing in normal young adults and in patients with insulinoma. PMID- 4313183 TI - Cortical influence on single neurons of the lateral reticular nucleus of the cat. PMID- 4313184 TI - Characteristic features of augmenting and recruiting responses in the cerebral cortex. PMID- 4313185 TI - Depression of centrum medianum complex response by rostral thalamic lesion. PMID- 4313186 TI - A study of pituitary and adrenal function in patients with traumatic injuries of the spinal cord. PMID- 4313187 TI - Prospects for the use of double-stranded ribonucleic acid (poly I:C) inducers in man. PMID- 4313188 TI - Variability of herpes simplex virus: isolation of two variants from simultaneous eruptions at different sites. PMID- 4313190 TI - Methylcholanthrene-induced hormonally active ovarian tumors in rabbits after two years of experimenting. PMID- 4313189 TI - Multisystem blood group study in trophoblastic disease. PMID- 4313191 TI - Mechanism of action of 2-mercapto-1(beta-4-pyridethyl)benzimidazole: a reversible inhibitor of interferon activity. AB - 2-mercapto-1(beta-4-pyridethyl)benzimidazole (MPB) inhibited the development of antiviral activity induced by interferon in chick cells. The MPB effect was reversed by washing the cells. The action of MPB was on a step immediately following interferon binding but before the cellular RNA and protein synthesis that appear to be required for interferon action. The step blocked by MPB possibly involves cellular phospholipid synthesis. PMID- 4313192 TI - Induction of stalk cell differentiation by cyclic AMP in the cellular slime mold Dictyostelium discoideum. AB - Cyclic AMP, which is a cell attractant (acrasin) for Dictyostelium discoideum, will cause isolated, unaggregated cells to turn directly into stalk cells containing thick celluloselike walls and large vacuoles. From previous work we know that in the cell mass, acrasin is produced solely in the region of stalk formation during fruiting, that stalk formation involves a high level of catabolism, and that cyclic AMP stimulates catabolic enzymes in other systems. These facts obviously suggest that in the development of D. discoideum, cyclic AMP might be a key factor in stalk cell differentiation. PMID- 4313193 TI - Electron spin resonance studies of lipid-protein interaction in human serum lipoproteins. AB - Spin-labeled derivatives of high density (HDL) and low density (LDL) lipoproteins from human serum were prepared with N-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl) maleimide. At the low ratios of spin label to protein employed, no changes in circular dichroism or immunochemical reactions were detected. The lipoprotein derivatives, labeled in their protein moieties, exhibited electron spin resonance spectra containing signals of strongly immobilized and weakly immobilized components. The strongly immobilized component was relatively more prominent in high density than in low density lipoproteins. Delipidation or addition of detergent greatly reduced the relative magnitude of the highly-immobilized signal. Reaction with specific antibodies did not alter the signals of spin labeled lipoproteins or apoproteins. The signals of the reconstituted complex of spin-labeled apoHDL-phospholipid were indistinguishable from those of a spin labeled apoHDL in the absence of lipid. PMID- 4313194 TI - A study on the transcription of the polyoma viral genome. AB - The transcription of polyoma (Py) viral RNA was studied in primary mouse kidney cell cultures (a) during normal, asynchronous infection, (b) under conditions where Py-induced DNA synthesis was inhibited with 5-fluorodeoxyuridine, and (c) after the synchronized onset of Py-induced DNA synthesis. The results obtained suggest that the bulk of Py RNA transcribed after the (asynchronous or synchronized) onset of Py-induced DNA synthesis, designated as "late" Py RNA, corresponds to the polycistronic transcript of most or all of the genetic information contained in a strand of circular Py DNA. The rate at which late Py RNA is transcribed is related to the amount of free Py DNA present in the cultures. Py-infected cultures contain a second, minor component of Py RNA (of one or possibly more species), designated as "early" Py RNA. At least some of this RNA continues to be transcribed if Py-induced DNA synthesis is inhibited with 5-fluorodeoxyuridine and, possibly, also late during normal infection. PMID- 4313195 TI - Trans-species rescue of defective genomes of murine sarcoma virus from hamster tumor cells with helper feline leukemia virus. AB - This report describes a trans-species rescue of defective MSV genome with helper leukemia virus derived from cats. This rescue was achieved by in vitro co cultivation of hamster tumor cells with feline embryo cells in the presence of helper feline leukemia virus (FeLV), or by inoculation of tumor cells into FeLV infected newborn cats. The rescued focus-forming viruses produced foci in feline embryo cultures but not in cultures of mouse, rat, and hamster species. One isolate was tested and found to induce sarcoma in a kitten. Antigenic and viral interference studies indicated that the focus-forming virus has the viral envelope of FeLV. Virus stocks consisted of a mixture of focus-forming particles and a 1000-fold excess of helper FeLV. Virus assay pattern in feline embryo cultures with or without added helper FeLV indicated that this helper virus is required for the transformation of feline cells. PMID- 4313196 TI - Parathyroid hormone, 3'5' AMP, Ca++, and renal gluconeogenesis. AB - Isolated segments of renal tubules prepared from rat kidney cortex were capable of sustained rates of gluconeogenesis when lactate served as substrate. An increase in external Ca(++), or the addition of parathyroid hormone at a fixed Ca(++) concentration led to enhanced rate of gluconeogenesis. However, parathyroid did not increase gluconeogenesis in the absence of external Ca(++) even though it caused a rise in 3'5' AMP whether Ca(++) was present or absent. Metabolite profiles showed that either an increase in external Ca(++), or the addition of hormone in the presence of calcium led to qualitatively very similar changes. However, the addition of hormone had little effect upon metabolite levels in the absence of extracellular calcium even though an increase in extracellular H(+) enhanced gluconeogenesis under similar conditions. These results are discussed in relationship to the close association of 3'5' AMP and Ca(++) in a variety of cellular systems. PMID- 4313197 TI - Effects of glucose on glycogen synthetase, phosphorylase, and glycogen deposition in the perfused rat liver. AB - An increase in the perfusate glucose concentration from near zero to about 11 mM increased glycogen synthesis in the perfused, isolated rat liver from zero to a value about half the maximum seen in the intact animal. Increased synthesis appeard to due not only to provision of substrate but also to conversion of glycogen synthetase to the active form and of glycogen phosphorylase to the inactive form. These glucose effects, which are apparently independent of changes in levels of hormones or adenosine 3':5'-cyclic phosphate, may be physiologically significant for control of the blood glucose level. PMID- 4313198 TI - Structural studies on reovirus: discontinuities in the genome. AB - The double-stranded RNA genome of reovirus breaks reproducibly into ten segments upon extraction from purified virions. Reovirus-induced messenger RNA's formed in infected cells correspond in length to these ten genomic segments and some real structural and biological implication must be accorded to the ready manner in which the genome is fragmented on attempted isolation. In the present work we have posed the question whether the reovirus genome is a continuous, double stranded molecule or whether there are discontinuities in the complementary strands of RNA that might constitute "weak points" in the structure. To answer this question, a method was developed to estimate the 3'-terminal nucleosides of RNA within intact virions. Approximately as many 3'-ends are free inside the virion as in RNA extracted from purified virus. Thus, the viral genome exists as a discontinuous structure inside the virus particle and both strands of the duplex are interrupted at intervals. PMID- 4313200 TI - Inhibition of hormone-sensitive adenyl cyclase by phenothiazines. AB - Chlorpromazine (3 x 10(-4)M) prevents the stimulation of adenyl cyclase activity in thyroid membranes produced by thyrotropin and prostaglandin, ACTH stimulation of adenyl cyclase in adrenal tissue, and glucagon- and epinephrine-stimulation of adenyl cyclase activity in liver. Baseline activity is unaffected. Parathyroid hormone stimulation of kidney preparations was not inhibited under these conditions. At chlorpromazine concentrations >3 x 10(-4)M F(-)-stimulated cyclase activity of thyroid and adrenal tissue was increased. Other phenothiazines, trifluoperazine, and prochlorperazine, have similar effects on thyrotropin and F( )-stimulated cyclase activity of thyroid. Na(+)- K(+)-dependent ATPase of thyroid is also inhibited by chlorpromazine. Since thymol causes a similar dissociation of hormone- and F(-)-stimulated adenyl cyclase, it is concluded that the surface properties of these agents best account for their effects on adenyl cyclase. PMID- 4313199 TI - Effect of thyrocalcitonin on adenosine 3':5'-cyclic phosphate formation by rat kidney and bone. AB - Thyrocalcitonin (TCT) increased the rate of accumulation of adenosine 3':5' cyclic phosphate (cyclic AMP) when added to incubations containing washed particles from whole rat kidney, adenosine triphosphate (ATP), MgSO(4), and caffeine. The maximum stimulatory effect of TCT, 44 +/- 6.7 per cent, was always less than the 150 to 250 per cent increase produced by parathyroid hormone (PTH). The effect of both hormones together was no greater than that of PTH alone when each was present at a maximally effective concentration. Since neither TCT nor PTH altered the rate of degradation of cyclic AMP by the kidney preparation, it may be inferred that their effects on cyclic AMP accumulation are the result of increased formation of cyclic AMP. Adenyl cyclase activity in homogenates of renal cortex was stimulated to a greater extent by TCT and PTH than was that of medulla, whereas, as reported earlier, the effect of vasopressin was much larger with homogenates of medulla. The accumulation of cyclic AMP in incubations of rat kidney cortex slices was increased 20 to 60 per cent by TCT and 50 to 140 per cent by PTH. The accumulation of cyclic AMP in incubations of rat calvaria was increased about threefold with TCT and nine to tenfold with PTH, while reduced and alkylated TCT had less than 10 per cent of the activity of TCT. These observations are consistent with the view that the physiological effects of TCT and PTH in kidney and bone are secondary to the enhanced formation of cyclic AMP. PMID- 4313202 TI - Deviant illness behaviour: patients of mesmerists. PMID- 4313201 TI - The effect of sodium hypochlorite on Ascaris eggs and cysts of Entamoeba histolytica. PMID- 4313203 TI - [Research on blood adrenaline changes in experimental endotoxin shock]. PMID- 4313204 TI - Host parasite relationships of chimpanzee viruses. ARL-TR-69-9. PMID- 4313205 TI - [Age dependent histochemical changes in the thymus of the Wistar rat]. PMID- 4313206 TI - [Structure and histochemistry of the integument of Echinorhynchus gadi muller (Acanthocephala)]. PMID- 4313207 TI - Discussion: the nature of the Le-a and Le-b antigens in human plasma. PMID- 4313208 TI - Concentration of viruses from sewage and excreta on insoluble polyelectrolytes. AB - The concentration of viruses from sewage by adsorption on and elution from an insoluble cross-linked copolymer of maleic anhydride is described. Viruses either added to sewage or naturally contained in sewage were preferentially adsorbed to this polyelectrolyte at a pH range of 5.0 to 6.0 and were eluted at pH 8.0 to 9.0. In a 2-month survey of viruses in sewage in the spring (April to May 1968), when viruses are at low levels, efficient and economical detection of these agents was accomplished with the polyelectrolyte-concentration method. This method lends itself to the detection of viruses present in minute amounts in fecal samples, urine, sewage, and other natural waters. Large volumes of these fluids can be treated with the polymer described, and virus can be concentrated sufficiently for detection. PMID- 4313210 TI - VERO cells (Cercopithecus aethiops kidney)--growth characteristics and viral susceptibility for use in diagnostic virology. (Brief report). PMID- 4313209 TI - Survival of human pathogens in composted sewage. AB - Studies were conducted to assess the effectiveness of an aerobic composter in destroying pathogens that may possibly be present in raw sewage sludge. Experiments conducted in this study were designed to determine whether or not selected indicator organisms (i.e., Salmonella newport, poliovirus type 1, Ascaris lumbricoides ova, and Candida albicans) could survive the composting process. The results of the assay showed that after 43 hr of composting, no viable indicator organisms could be detected. The poliovirus type I was the most sensitive, being inactivated within the first hour, whereas C. albicans was the most resistant, requiring more than 28 hr of composting for its inactivation. The data from this study indicated that aerobic composting of sewage sludge would destroy the indicator pathogens when a temperature of 60 to 70 C is maintained for a period of 3 days. PMID- 4313211 TI - Dynamic aspects of sleep disturbance in relation to mental illness. PMID- 4313212 TI - An analysis of the electron spin resonance of low spin ferric heme compounds. AB - The electron spin resonance spectra of low spin ferric heme proteins are calculated and compared with experimental spectra recently obtained for a large number of heme proteins. On the basis of observed g values, these heme proteins have been categorized into five prototypes. Since electron spin resonance spectra are quite sensitive to small changes in the local environment about the paramagnetic ion, we have explored in some detail, the possibility that the g value variation in these different types of proteins is due to systematic environmental changes. To this end, we have calculated the g values as a function of tetragonal and rhombic distortions and compared our results with observed behavior. In addition we have also calculated the energy intervals between the low spin states in zero magnetic field and the temperature dependent magnetic moments and studied the effect on these properties also of small symmetry changes. PMID- 4313213 TI - Combined irradiation modalities in the therapy of malignant lymphoma with chylothorax. Case report. PMID- 4313215 TI - [Sensitivity of a referent human diploid cell strain WI-38 to different viruses. II]. PMID- 4313214 TI - Adenovirus infections in Manitoba. AB - This review of adenovirus infections in Manitoba over a five-year period is introduced with a brief presentation on the structure-function relationships of the adenoviruses. Extensive research has resulted in the accumulation of a great deal of basic information, far surpassing our knowledge about the infections that these viruses produce in man. More research is needed on the epidemiological and clinical aspects of these diseases, including methods for prevention and treatment, and earlier methods of diagnosis.Features of 216 adenovirus respiratory infections diagnosed from 1963 to 1967 are reviewed and presented. All infections were diagnosed by showing a four-fold or greater increase. In addition, an adenovirus was isolated from many of the infections. These infections occurred every year in substantial numbers and they were seen during each month of the year, although they were more frequent and severe in the winter. Infants and younger persons were often affected. The most severe disease was a pneumonitis which occurred mainly in infants. Associated symptoms usually arose from the gastrointestinal tract, and were sufficiently common to indicate that one should suspect an adenovirus infection when respiratory and gastrointestinal symptoms occur together in a child.The possible role of adenoviruses in the etiology of other than respiratory diseases is discussed and the features of 96 possible non-respiratory infections are presented. Further work will be required to establish a definite etiologic role of the adenoviruses in most of these infections. PMID- 4313216 TI - A progeria-like syndrome produced by dihydrotachysterol: its prevention by conjugated estrogens (Premarin). PMID- 4313217 TI - Review of results in a geriatric intensive treatment unit: some prospects. PMID- 4313218 TI - Clinicopathologic conference: hepatic failure with clonorchiasis. PMID- 4313219 TI - Benign vaginal tumor coexistent with squamous-cell carcinoma in situ of cervix. PMID- 4313220 TI - [Current problems of chemical cancerogenesis]. PMID- 4313222 TI - Ultrastructure of cortical synapses after failure of presynaptic activity in ischemia. PMID- 4313221 TI - [Cylindroma or adenoid cystic carcinoma. Our personal case of cylindroma of the hard palate]. PMID- 4313224 TI - Effect of phytohemagglutinin on enzymes of thymidine salvage pathway of cultured chronic lymphatic leukemic lymphocytes. PMID- 4313225 TI - Genetic modes of transmission in metabolic bone disease. PMID- 4313223 TI - A possible mechanism for the erythrocytosis associated with hepatocellular carcinoma in man. PMID- 4313227 TI - [Anthracofibrosis in the carbon black industry. (Carbon pneumoconiosis)]. PMID- 4313226 TI - Cystic and pseudocystic lesions of the terminal phalanx with special reference to epidermoid cysts. PMID- 4313228 TI - A new virus of minimal pathogenicity associated with Friend virus. II. Histological changes and immunodepressive effect. PMID- 4313230 TI - Transformation of hamster cells in vivo and in vitro by an adenovirus 4-SV40 hybrid. PMID- 4313229 TI - The distribution of the mouse mammary tumor agent and its antigenicity in milk. PMID- 4313231 TI - Monkey-mouse hybrid cell lines containing the SV40 genome in a partially repressed state. PMID- 4313232 TI - The pattern of protein synthesis in SV40-infected CV-1 cells. PMID- 4313233 TI - Structural proteins of murine erythroblastosis virus. PMID- 4313234 TI - A new virus of minimal pathogenicity associated with Friend virus. I. Isolation by end-point dilution. PMID- 4313235 TI - [Tarsal tunnel syndrome]. PMID- 4313236 TI - Fourteenth Bowditch lecture. Blood-borne signals. The measuring and modelling of humoral communication and control. PMID- 4313237 TI - [Massive rise in S.G.O.T. in cardiology (Literature review apropos of 6 cases)]. PMID- 4313238 TI - [Acute edematous polymyositis]. PMID- 4313239 TI - [Progestogens in the treatment of advanced breast cancer. Clinical study of norethisterone acetate]. PMID- 4313240 TI - [Bone lesions observed in serological trepanematosis. Study of 267 patients]. PMID- 4313241 TI - [Aseptic necrosis of the femoral head and drepanocytosis in a Moroccan woman]. PMID- 4313242 TI - Microbiological aspects of radiopasteurized chicken. NYO-3733-4. PMID- 4313243 TI - Microbiological aspects of radiopasteurized chicken. NYO-3733-7. PMID- 4313244 TI - Microbiological aspects of radiopasteurized chicken. NYO-3733-6. PMID- 4313245 TI - Microbiological aspects of radiopasteurized chicken. NYO-3733-5. PMID- 4313246 TI - Microbiological aspects of radiopasteurized chicken. NYO-3733-3. PMID- 4313248 TI - [The effect of vitamins C, B-1 and B6 on adrenal function in patients with atherosclerotic cardiosclerosis]. PMID- 4313249 TI - [Correction of the frequently occurring syndactylia (modified surgical technic)]. PMID- 4313247 TI - [A comparative study of various methods of determining riboflavin in food products]. PMID- 4313250 TI - Bone age in short boys and tall girls. PMID- 4313251 TI - Epidemiology of primary central nervous system neoplasms. I. Mortality from primary central nervous system neoplasms in Minnesota. PMID- 4313252 TI - Antigenic characterization of parainfluenza 4A and 4B by the hemagglutination inhibition test and distribution of HI antibody in human sera. PMID- 4313253 TI - Antigenic segregation of type 2 poliovirus isolants related and unrelated to Sabin's vaccine strain with modified Wecker technique. PMID- 4313254 TI - Cytomegalovirus isolations associated with pregnancy wastage. PMID- 4313255 TI - Genital herpesvirus (type II) strain differences. PMID- 4313256 TI - The use of multivariate techniques in the study of skeletal populations. PMID- 4313257 TI - Paleodemography of India and Ceylon since 3000 B.C. PMID- 4313258 TI - Approaches to the study of developmental variability in human skeletal populations. PMID- 4313260 TI - Nutritional stress and growth: sex difference in adaptive response. PMID- 4313259 TI - Paleodemography and evolution. PMID- 4313262 TI - Bluetongue virus in white-tailed deer. PMID- 4313261 TI - Neutralizing antibody in experimentally induced respiratory infection in calves. PMID- 4313263 TI - Marek's disease: application of immunofluorescence for detection of antigen and antibody. PMID- 4313264 TI - Lipid utilization in polyoma virus-infected mouse embryo cells. PMID- 4313265 TI - Granular cell myoblastoma of the bronchus. Long-term follow-up after its local resection. PMID- 4313266 TI - [Histologic study of perineural metastases of spinocellular epithelioma]. PMID- 4313267 TI - [Milker's nodes]. PMID- 4313268 TI - Milker's nodule. A clinical and electron microscopic report. PMID- 4313269 TI - [Etiology of epiphysiolysis (epiphysiolisthesis) of the femur head]. PMID- 4313271 TI - The biochemistry and pharmacology of the D-state (dreaming sleep). PMID- 4313270 TI - Death and transfiguration of a problem. PMID- 4313272 TI - Drugs and dreams. IV. Tranquilizers and their effects upon dreams and dreaming in schizophrenic patients. PMID- 4313273 TI - Some considerations of motor and electrical activity in states of diminished awareness. PMID- 4313274 TI - Micromethods for respiratory virus sero-epidemiology. PMID- 4313275 TI - Enzyme histochemistry of the normal and atherosclerotic canine aorta. PMID- 4313276 TI - Effect of prolonged incubation on untyped enteroviruses. PMID- 4313277 TI - Studies of variola virus and immunity in smallpox. I. Variola virus hemagglutinins. PMID- 4313278 TI - Observations on childhood infections with the Epstein-Barr virus. PMID- 4313280 TI - Hepatitis in marmosets. PMID- 4313279 TI - Equine interferon: characterization of a viral inhibitor induced in equine kidney cell cultures with statolon. PMID- 4313281 TI - Hepatitis in marmosets. PMID- 4313282 TI - Neurologic abnormalities complicating severe renal disease. PMID- 4313283 TI - Unitary multiple-spiked responses in cat inferior olive nucleus. PMID- 4313284 TI - Long inhibitory and excitatory pathways converging onto cat reticular and Deiters' neurons and their relevance to reticulofugal axons. PMID- 4313285 TI - Discrimination of different spinal monosynaptic pathways converging into reticular neurons. PMID- 4313286 TI - Renshaw cell mediated inhibition of Renshaw cells: patterns of excitation and inhibition from impulses in motor axon collaterals. PMID- 4313287 TI - Transfer characteristics of excitation and inhibition in cat retinal ganglion cells. PMID- 4313288 TI - Transfer characteristics of excitation and inhibition in the human visual system. PMID- 4313289 TI - Electrophysiological evidence for a mossy fiber input to the cerebellar cortex activated indirectly by collaterals of spinocerebellar pathways. PMID- 4313291 TI - Hospital-acquired herpes zoster following exposure to chickenpox. PMID- 4313290 TI - An evaluation of 10 years' experience with retroperitoneal lymph node dissection for Wilms' tumor. PMID- 4313293 TI - Viral infections in a large urban hospital. PMID- 4313292 TI - Microangiopathic hemolytic anemia with recovery after removal of a huge leiomyoblastoma. PMID- 4313294 TI - Neurotrophic control of protein synthesis in the regenerating limb of the newt, Triturus. PMID- 4313295 TI - Active water-insoluble derivative of renin. PMID- 4313296 TI - Self-annealing of subgroup 2 myxovirus RNAs. PMID- 4313297 TI - Positive alpha-1-foetoprotein tests in pyridoxine deprived baboons: relevance to liver carcinoma in Africans. PMID- 4313298 TI - [Adrenal cortex hyperfunction in the course of lung carcinoma. A case report]. PMID- 4313299 TI - [Hypoglycemia and primary liver cancer. Hormone levels. Action of diazoxide]. PMID- 4313300 TI - Delta-aminolevulinic acid synthetase: induction in embryonic chick liver by glucagon. AB - Glucagon elicits a twofold increase in delta-aminolevulinic acid synthetase activity in the livers of 18-day-old chick embryos. This rise occurs when RNA synthesis is inhibited, but is prevented when protein synthesis is blocked. Cyclic adenosine monophosphate appears not to be involved. PMID- 4313301 TI - Preparation of beating heart cells from adult rats. AB - Suspensions of cardiac cells have been prepared from fragments of hearts from adult rats by prolonged incubation with trypsin and collagenase. In these preparations, about 50 percent of the viable cells routinely exhibit spontaneous contractions ranging from 20 to 120 beats per minute at room temperature. The contractile activity is essentially lost at 2 degrees C but returns to normal as the temperature is increased. The rate of cellular contractions and the percentage of total cells exhibiting contractility are influenced by experimental conditions of cell preparation and the composition of the suspending medium. PMID- 4313302 TI - Intestinal enzymes: indicators of proliferation and differentiation in the jejunum. AB - Some intestinal enZymes were assayed which were related to: (i) Cellular proliferation, for example, aspartate carbamoyltransferase, thymidine kinase, uridine kinase, and dihydroorotase; (ii) cellular differentiation, for example, lactase, invertase, maltase, alkaline phosphatase, and dipeptidase; and (iii) lysosomes, for example, beta-glucuronidase, acid beta-galactosidase, and acid phosphatase. These enzymatic determinations can be used to distinguish the crypt from the villus during healthy or diseased states. PMID- 4313303 TI - Benign mesenchymoma. PMID- 4313304 TI - Alveolar cell carcinoma. PMID- 4313305 TI - Treatment of the Wilms' tumor with actinomycin D. PMID- 4313307 TI - [A rare case of granular cell myoblastoma of vulvar localization]. PMID- 4313308 TI - [Results of a cooperative clinical study of the new antineoplastic antibiotic rubomycin]. PMID- 4313309 TI - [Use of human leukocytic interferon fro the treatment of viral eye diseases]. PMID- 4313310 TI - Isolation of ether-resistant enteroviruses from sewage: methodology. AB - Experiments were conducted to determine whether polio type 1 (Mahoney and coxsackie A8 viruses adsorb onto cotton fibers of sewer swabs. Negative results were obtained. It has been shown that viruses may exist in sewage as free virus particles or as bound (adsorbed) virus particles. The sewer-swab method of sampling is superior because it filters out the bound virus over several days; when collected, it represents a catch (grab) sample at that particular time which may or may not contain free virus. A simple method for the preparation of sewage inocula for virus isolations is described which samples the bound virus fraction. Only ether-resistant viruses can be isolated, and an ultracentrifuge is not required. By this method, an isolation rate between 60 and 80% of positive sewer swabs can be achieved. Corresponding figures of 84 and 96% were achieved by concentration of sewer-swab eluates with an ultracentrifuge. Quantitative studies showed that the virus concentration in raw sewage can be as high as one infectious particle per 0.5 ml. PMID- 4313311 TI - Potentially infectious agents associated with shearling bedpads. I. Effect of laundering with detergent-disinfectant combinations on polio and vaccinia viruses. AB - Glutaraldehyde-tanned woolskin pads which are used for the prevention of decubitus ulcers in bed patients were experimentally contaminated with polio or vaccinia viruses. Two methods of exposure, direct contact and aerosol, were used in separate experiments. Attempts were made to remove or inactivate these virus contaminants by laundering the woolskins in a quaternary ammonium disinfectant, a phenolic disinfectant, or alkalinized glutaraldehyde, in combination with an anionic detergent or a nonionic detergent. The effect of a commercial detergent sanitizer was also studied. The virus titers were significantly reduced in all experiments, but only laundering in glutaraldehyde in combination with either detergent lowered the vaccinia virus titers to below detectable limits. High concentrations of glutaraldehyde altered the texture of the wool and leather apparently by precipitating a component of the detergent onto the fibers. In all the poliovirus experiments, the virus was still detectable on either or both the wool and the leather of the pads after laundering. The rinse water from each experiment was tested for the presence of virus. No vaccinia virus was recovered, but poliovirus was demonstrated in titers up to 10(3) cell culture 50% infectious doses. PMID- 4313313 TI - Detection of agglutinins in chickens infected with JM leukosis virus. AB - Hemagglutinins for sheep red blood cells were detected in sera from JM virus infected single-comb White Leghorn (susceptible S line) chickens. The agglutinins were not sedimented at 97,000 x g and were not affected by freezing and thawing, possibly indicating a soluble hemagglutinating factor. Agglutination titers were read in a relatively short period, after 4 hr of incubation at 4 C. The usefulness of this test for quick and low-cost screening of a large number of samples is indicated. PMID- 4313312 TI - Susceptibility of genital mycoplasmas to antimicrobial agents. AB - The susceptibility of 11 T-strains, 12 strains of Mycoplasma hominis, and a single strain of M. fermentans to 15 antimicrobial agents was determined by study of inhibition of metabolic activity in a broth dilution system. All three species were inhibited by tetracycline, chloramphenicol, streptomycin, gentamicin, and kanamycin, and were relatively resistant to cephalothin, cephaloridine, polymyxin, vancomycin, and ampicillin. Three antimicrobial agents had significant differential effects on these species. Erythromycin was more active against T strains than against M. hominis or M. fermentans. Lincomycin, clindamycin, and nitrofurantoin had greater activity against M. hominis and M. fermentans than against T-strains. The activity of the drugs tested was generally uniform over a wide range of inocula. The effect of pH and the difference between minimal inhibiting and minimal mycoplasmacidal concentrations of the drugs tested were consistent with expectations based on the effects of these drugs on bacteria. PMID- 4313315 TI - Miniature cell culture systems for use in field isolation of viruses: cell stability and sensitivity to selected laboratory-propagated viruses during storage in miniaturized environments. AB - Cell cultures were miniaturized in 1-dr vials or in capillary tubes (100 by 3 mm) and examined for their capacity to maintain normal gross morphology and sensitivity to infection by viruses during storage under a variety of conditions. The purpose of these studies was to determine the feasibility of using such cultures in the field during epidemiological investigations. From the results of this work it was concluded that such a feasibility exists. PMID- 4313314 TI - Polymyxin-coagulase-mannitol-agar. I. A selective isolation medium for coagulase positive Staphylococci. AB - A selective, differential plating medium was developed for the isolation and identification of coagulase-positive and mannitol-fermenting staphylococci. Coagulase produced by growing Staphylococcus aureus caused an opaque zone of fibrin to form around each colony. Several strains of S. aureus produced a visible coagulase reaction by 8 hr, and all strains gave a positive reaction before 12 hr. Mannitol fermentation was usually observed between 12 and 36 hr. Rabbit serum was filtered through Sephadex G-100 to obtain plasmin- and plasminogen-free coagulase-reacting factor (CRF). False-negative reactions, caused by staphylokinase and staphylococcal Muller factor action on plasminogen, were eliminated when this CRF was used. False-positive reactions by lipolytic, coagulase-negative staphylococci were reduced, since gel filtration removed the serum lipoprotein which served as a primary source of opacity. The addition of 75 mug of polymyxin B per ml selectively retarded the growth of S. epidermidis and minimized false-positive reactions caused by citrate-utilizing gram-negative rods. The preparation, characteristics, and use of the medium are presented. PMID- 4313316 TI - Test method for determining the viricidal activity of disinfectants against vesicular stomatitis virus. AB - A test method using embryonating chicken eggs for the evaluation of several types of disinfectants as viricides against vesicular stomatitis virus was developed which gave specific, reproducible results. PMID- 4313317 TI - Inactivation of vesicular stomatitis virus by disinfectants. AB - Twenty-four chemical disinfectants considered to be viricidal were tested. Ten disinfectants were not viricidal for vesicular stomatitis virus within 10 min at 20 C when an LD(50) titer of 10(8.5) virus units per 0.1 ml were to be inactivated. Quantitative inactivation experiments were done with acid, alkaline, and a substituted phenolic disinfectant to determine the kinetics of the virus inactivation. Substituted phenolic disinfectants, halogens, and cresylic and hydrochloric acids were viricidal. Basic compounds such as lye and sodium metasilicate were not viricidal. PMID- 4313318 TI - [Detection of a new variant of the type A Colombia aphthous virus (A27)]. PMID- 4313319 TI - Continuation of studies on the incidence and distribution of different types of foot-and-mouth disease virus in India. PMID- 4313320 TI - [New studies of the frequency and distribution of the different types of aphthous virus in India]. PMID- 4313321 TI - [Quantitative seroprecipitation. Control technic used in a laboratory unit producing antiaphthous vaccine]. PMID- 4313322 TI - [Identification of types of aphthous virus]. PMID- 4313323 TI - [Identification of the types of aphthous virus. Nong Sarai (Thailand)]. PMID- 4313324 TI - [Release of NADH-cytochrome c reductase in rat plasma after CCl4 poisoning]. PMID- 4313325 TI - A discussion of the neurophysiological basis of disturbances in consciousness: a case report in the pons tumor. PMID- 4313327 TI - Verxite flakes for in vivo binding of cesium-134 in cows. PMID- 4313326 TI - Percent cesium-134 and strontium-85 in milk, urine, and feces of goats on normal and verxite-containing diets. PMID- 4313328 TI - Nutritional requirements of rat ascites hepatoma cells of strain JTC-16 (AH-7974) in tissue culture. PMID- 4313329 TI - The virulence to rats of five Entamoeba histolytica-like strains capable of growth at 25 degrees C and attempts to discover simular strains. PMID- 4313330 TI - Isolation and partial characterization of a major inositol-containing lipid in baker's yeast, mannosyl-diinositol, diphosphoryl-ceramide. AB - A polar lipid containing about 20 per cent of the lipid soluble inositol has been purified from cells of Saccharomyces cerevisiae. This compound labeled with (3)H inositol, (32)P(i), or (14)C glucose was isolated from aqueous pyridine extracts by means of paper chromatography. Unlabeled compound was obtained by a differential solubility scheme. Analytical and degradation studies suggest that this compound can be formulated as a mannosyl-diinositol, diphosphoryl-ceramide. It can be converted by treatment with base or acid into a mannosylmonoinositol phosphoryl-ceramide, a composition which relates it to the basic structure of the phytoglycolipids. PMID- 4313331 TI - Transport changes rapidly initiated by serum addition to "contact inhibited" 3T3 cells. AB - Two- to fourfold increases in uridine and phosphate uptake were brought about within 10 to 15 minutes after adding fresh serum to confluent 3T3 cells. The stimulation of transport was specific, since no serum effect was observed for 3-O methyl-D-glucose or amino acids. The early increase in RNA labeling, previously identified by (14)C-uridine incorporation, could be accounted for by this transport effect. Increased labeling with (32)P-phosphate of at least five phospholipids occurred soon after adding serum. This increase, however, could not be accounted for by increased transport. Both of these results suggest that specific early membrane changes are involved in "contact inhibition."The following results are consistent with this suggestion. Uptake of uridine and phosphate by nonconfluent 3T3 cells was higher than by confluent cells and was only slightly increased by fresh serum. In contrast, uptake of these substrates by Polyoma virus-transformed 3T3 cells, which are not subject to "contact inhibition," was not significantly decreased after the cells became confluent, and serum addition had no effect on transport by either nonconfluent or confluent Polyoma virus-transformed 3T3 cells. Fractionation of serum on Sephadex G-200 demonstrated that the factor which stimulated phosphate transport was different from the previously identified factor which stimulates DNA synthesis by confluent 3T3 cells. PMID- 4313332 TI - Hybridization of RNA from Rous sarcoma virus with cellular and viral DNA's. AB - The RNA of Rous sarcoma virus (RSV) hybridizes with DNA's isolated from all eukaryotes tested (animal and plant) with the possible exception of yeast. Bacterial DNA's show no homology to RSV-RNA. DNA's from the oncogenic viruses, adenovirus type 12 and SV40 show significant homology with RSV-RNA, but those from nononcogenic adenoviruses types 2 and 4 are not homologous.RSV-RNA hybridized to all of the DNA's examined has the same, or a closely similar, base composition. Moreover, the melting temperatures of all of the hybrids analyzed are very similar, further suggesting that a common base sequence in DNA functions in hybridization with RSV-RNA. PMID- 4313333 TI - Inhibition of herpes simplex virus by synthetic double-stranded RNA (polyriboadenylic and polyribouridylic acids and polyriboinosinic and polyribocytidylic acids). AB - Two-stranded polyriboadenylic and polyribouridylic acids and polyriboinosinic and polyribocytidylic acids protect against herpes simplex virus-induced cytopathogenicity in HEp 2 cultures, systemic herpes simplex virus infection in mice, and herpes simplex virus-induced keratoconjunctivitis in rabbits. PMID- 4313335 TI - Activation of rabbit liver fructose diphosphatase by coenzyme A and acyl carrier protein. AB - The catalytic activity of rabbit liver fructose diphosphatase is enhanced more than fourfold by treatment with coenzyme A or acyl carrier protein. Other sulfhydryl compounds, such as glutathione or cysteine, are without effect. Activation is reversed by reduced glutathione or cysteine, indicating that the enzyme and activator are linked by disulfide bridges. The activated enzyme derivative can be formed by a disulfide exchange reaction at alkaline pH or by an oxidation reaction which proceeds at neutral pH. The latter process requires O(2) and Cu(++), and is inhibited by EDTA. PMID- 4313334 TI - On the role of DNA synthesis in avian tumor virus infection. AB - Preinfection of chick embryo fibroblasts with an avian tumor virus does not eliminate the requirement of early DNA synthesis for other avian tumor viruses superinfecting the same cells several days after the primary inoculum. The function served by the early DNA in avian tumor virus infection either fails to persist into late infection or is genetically specific for each viral type. PMID- 4313336 TI - Marek's disease herpes virus: a cytomegalovirus. AB - The DNA of herpes viruses associated with Marek's disease of fowl contains 56-57 moles of guanine and cytosine per 100. The composition of its DNA and lack of infectiousness of cell-free preparations suggest that the herpes virus associated with Marek's disease belongs to the herpes virus group B which contains predominantly cytomegaloviruses. PMID- 4313338 TI - [Phases and cycles of nocturnal sleep in epileptic patients. Statistical study of 87 poligraphic recordings]. PMID- 4313337 TI - A stimulation by cyclic 3',5'-adenosine monophosphate of amino acid activation and polymerization in reticulocyte hemolysates. AB - With reticulocyte supernatant, cyclic 3',5'-adenosine monophosphate at concentrations of 10(-3) to 10(-2)M causes stimulation of aminoacyl-tRNA synthetases for some, e.g., valine and leucine, but not all, amino acids; it is highest at nonsaturating concentrations of ATP. Similar concentrations of cyclic 3',5'-adenosine monophosphate are found to stimulate phenylalanine polymerization from phenylalanyl transfer ribonucleic acid on polyuridylic acid-charged reticulocyte ribosomes. The degree of stimulation is highest at low GTP concentrations. It is abolished by addition of phosphoenolpyruvate + pyruvate kinase, which stimulate similarly or more effectively at low GTP levels. Under the conditions of these experiments, cyclic 3',5'-adenosine monophosphate did not appreciably inhibit GTP hydrolysis. PMID- 4313339 TI - [Polyneuropathy due to lead poisoning from water pipes]. PMID- 4313340 TI - [Adrenocortical insufficiency and progressive encephalopathy. Clinical case]. PMID- 4313341 TI - [Reactive and dystrophic vascular changes in glioblastoma multiforme]. PMID- 4313342 TI - Pathology of ectopic ACTH syndrome with emphasis on pituitary Crooke cells and adrenocortical hyperplasia related to ACTH activities in tumor tissues. PMID- 4313343 TI - Cytochemical and ultrastructural studies of chromatolysis in neurones infected with Herpes simplex virus. PMID- 4313344 TI - [Gas gangrene of the stomach. A very rare location of gas edema]. PMID- 4313345 TI - [Biosynthesis and release of insulin in organ cultures of fetal rat pancreas]. PMID- 4313346 TI - [Metabolism and insulin secretion in isolated islets]. PMID- 4313348 TI - The adrenergic innervation in the esophagus and respiratory tract of the rabbit. PMID- 4313349 TI - [The importance of infection for respiratory allergies. V. The factors of specific and unspecific immunity in the patient serum]. PMID- 4313347 TI - [Control of ATP levels in stimulated pancreatic B-cells]. PMID- 4313351 TI - [Lipiodol neurography of the nervous ulnaris]. PMID- 4313350 TI - [Ameloblastic tumors of the maxilla. Statistical data]. PMID- 4313352 TI - [Water pollution of a viral nature]. PMID- 4313353 TI - A trial to obtain in vitro a metronidazol-resistant strain of Entamoeba histolytica. PMID- 4313354 TI - Janus green B and experimental syndactyly in chick embryos. PMID- 4313355 TI - Dopa-decarboxylase and monoamine oxidase activities in a transplantable islet cell tumor of the golden hamster. PMID- 4313356 TI - [Primary cancer of the liver]. PMID- 4313357 TI - [Synacthen Depot. Results of the clinical treatment in neurology. Preliminary note]. PMID- 4313358 TI - [Habit forming drugs (3): morphine addiction]. PMID- 4313359 TI - [Analysis of free amino acid pool and bound amino acids in the early period of cell infection with adenovirus]. PMID- 4313360 TI - Experimental model systems of pneumoconiosis. I. The effect of dusts on subcutaneous sponge implants in the rat. PMID- 4313361 TI - Experimental model systems of pneumoconiosis. II. The effect of direct and intravenous injection of silica on the rat liver. PMID- 4313362 TI - [Metastases in 1000 autopsies of bronchial cancer]. PMID- 4313363 TI - [A new virus disease of the fuso-spheroid group in the coleopteron Phyllopertha horticola L]. PMID- 4313364 TI - [Cortisolemia test after stimulation with synthetic adrenocorticotropic hormones (preliminary note)]. PMID- 4313365 TI - [Interferon in the treatment of virus diseases of the conjunctiva and the cornea]. PMID- 4313366 TI - [Bronchology of tuberculosis. Demonstration of tuberculoses in anomalies and non specific changes using a new contrast medium]. PMID- 4313367 TI - [Calcium retention from common diet in a selected group of preschool children]. PMID- 4313368 TI - [A rare case of abdominal wall synoialoblastoma]. PMID- 4313369 TI - [Experience in the tuberculin therapy]. PMID- 4313370 TI - [Association "epithelial cancer-acute leucosis". 6 personal cases]. PMID- 4313371 TI - [Diabetes mellitus and pulmonary tuberculosis. 200 cases of diabetes observed in East Algeria]. PMID- 4313372 TI - [Complete study of survival in 828 cases of cancer of the breast treated at the Rene-Huguenin Center in 10 years]. PMID- 4313373 TI - [Clinical pharmacology of synthetic ACTH derivatives]. PMID- 4313374 TI - [Contents of free 17-oxycorticosteroids in the blood of patients with lupus erythematosus]. PMID- 4313375 TI - [Hepatitis in monkeys following inoculation of adenovirus isolated from virus hepatitis patients. IV. Immunization and challenge trials]. PMID- 4313376 TI - [Radioautographic studies of DNA metabolism of monkey kidney tissue cultures following infection with SV-40 virus]. PMID- 4313377 TI - Comparison of pituitary-adrenocortical function in asthmatic patients given long term corticosteroid therapy and in asthmatics who have not received adrenal steroids. PMID- 4313378 TI - Chronic lactic acidosis in an adult. A new syndrome associated with an altered redox state of certain NAD-NADH coupled reactions. PMID- 4313379 TI - Abnormal responsiveness of the renin aldosterone system to acute stimulation in patients with essential hypertension. PMID- 4313380 TI - Overall regulation of the circulation. PMID- 4313382 TI - [Primary tumors of the pleura. II. Submesothelial tumors. (Anatomo-clinical considerations on 21 cases)]. PMID- 4313381 TI - Comparative physiology: chromatophores. PMID- 4313383 TI - [Nuclease inhibitors in animal tissues]. PMID- 4313385 TI - [Temporary gigantism in an amoeba of man]. PMID- 4313384 TI - [Arboviruses in Ivory Coast. Serologic survey in the human population]. PMID- 4313386 TI - [The treatment of some infantile malignant neoplasms with Vinca rosea alkaloids]. PMID- 4313387 TI - [Multivalent antibiotic allergy with penicillin and tetracycline anaphylaxis]. PMID- 4313388 TI - [Functional study of glyco-active adrenal glands in the aged patient. I. Steroidemia and steroiduria in basal conditions; load test with ACTH, 6-methyl prednisolone and desamethasone]. PMID- 4313389 TI - [Functional study of the glycoactive adrenal gland in the aged patient. II. Functional tests with metopirone, dexamethasone and bacterial pyretogen]. PMID- 4313390 TI - [Adrenal glands in the obese patient]. PMID- 4313392 TI - [Influence of paleocerebellum on the excitability of mesencephalic reticular formations and certain limbic structures]. PMID- 4313391 TI - Presence of life-shortening factors in spleens of aged mice of long lifespan and extension of life expectancy by splenectomy. PMID- 4313393 TI - [Correlation of summary and cell activity in the zone of focal pathology in brain]. PMID- 4313394 TI - [Dependency of electrical activity parameters in ventricular myocard fibers on frequency and duration of preceding excitation]. PMID- 4313395 TI - Sedimentable and non-sedimentable interfering components in mouse embryo cultures treated with molluscum contagiosum virus. PMID- 4313396 TI - Observations on the structure of the nucleocapsids of some paramyxoviruses. PMID- 4313398 TI - Factors affecting the growth of Rhinovirus 2 in suspension cultures of L132 cells. PMID- 4313397 TI - Patterns of cytopathology and lysosomal enzyme release in poliovirus-infected HEp 2 cells treated with either 2-(alpha-hydroxybenzyl)-benzimidazole or guanidine HCl. PMID- 4313400 TI - Dependence of murine sarcoma virus infection on the cell cycle. PMID- 4313399 TI - Infection of chick embryo fibroblasts with template active RNA from avian myeloblastosis virus. PMID- 4313401 TI - Observations on cultures of rabbit retina infected with vaccinia and herpes simplex virus. PMID- 4313402 TI - Identification of poliovirus temperature-sensitive mutants having defects in virus structural protein. PMID- 4313403 TI - An ultrastructural histochemical study of brown adipose tissue from neonatal rats. PMID- 4313404 TI - Immunofluorescent localization of vitamin D-dependent calcium-binding protein. PMID- 4313405 TI - [Note on protonation of caffeine]. PMID- 4313406 TI - [Hazards of anticoagulants as viewed by the neurologist]. PMID- 4313407 TI - Extracellular enzymes of Blastomyces dermatitidis. PMID- 4313409 TI - [Use of purified para-influenza virus-3-antigen in hemagglutination tests]. PMID- 4313408 TI - Effects of monovalent cations on the spontaneous transmitter release in the neuromuscular junction of toad in the presence of ethanol. PMID- 4313410 TI - [Usefulness of the hemagglutination inhibition test and the complement fixation test for detection of Sendai virus antibodies]. PMID- 4313411 TI - [The decline of persistent antibodies in patients with tumors]. PMID- 4313412 TI - [Determination of 4-hydroxy-3-methoxy-mandelic acid (vanillinmandelic acid) in the urine]. PMID- 4313413 TI - [The binding of thyroid hormones to human serum lipoproteins]. PMID- 4313414 TI - Causes of blindness in Sweden. PMID- 4313415 TI - Fluorescein angiography of the vessels of the iris in pseudoexfoliation of the lens capsule, capsular glaucoma and some other forms of glaucoma. PMID- 4313416 TI - An outbreak of acute respiratory disease in Trinidad associated with para influenza viruses. PMID- 4313417 TI - Antigenic variants of coxsackievirus type A24. PMID- 4313418 TI - Familial systemic paramyloidosis with lattice dystrophy of the cornea, progressive cranial neuropathy, skin changes and various internal symptoms. A previously unrecognized heritable syndrome. PMID- 4313419 TI - [The effect of quartz on the bacterial cell membranes by the example of Micrococcus lysodeicticus]. PMID- 4313420 TI - [Selective cultivation of coagulase-positive staphylococci from chopped meat]. PMID- 4313421 TI - [Comparative studies of pathogenicity determination in staphylococci]. PMID- 4313422 TI - [Importance and significance of guided virological studies in abacterial infectious diseases of the eye. I. Studies of the regional epidemic (kerato )conjunctivitis 1954-1964 in the region of Glauchau]. PMID- 4313424 TI - [Studies of the adsorption of lipids from erythrocyte membranes by silicogenic and nonsilicogenic dust]. PMID- 4313425 TI - Mode of action of viomycin on Rhizobium meliloti. PMID- 4313426 TI - An improved method for the preparation of a stable noninfective western equine encephalomyelitis diagnostic antigen. PMID- 4313423 TI - [Importance and significance of guided virological studies in abacterial infectious diseases of the eye. II. Studies of the infectious abacterial (kerato ) conjunctivitis from the university ophthalmological clinics of Leipzig]. PMID- 4313427 TI - Method for determining Bacillus thuringiensis var. thuringiensis Berliner in soil. PMID- 4313428 TI - Metabolism of Clostridium perfringens type A. I. Cultural conditions which provide stable cell suspensions. PMID- 4313430 TI - Herpetic whitlows: results of treatment with idoxuridine. PMID- 4313429 TI - Tentative method of analysis for antimony content of the atmosphere. 12102-01 69T. PMID- 4313431 TI - Eruptive histiocytoma in a dog. PMID- 4313433 TI - The prognosis in zoster paralysis. PMID- 4313432 TI - Symposium on immunity to selected canine infectious diseases. PMID- 4313435 TI - Retinal anlage tumor of the epididymis: a case report. PMID- 4313436 TI - Virilizing adrenal adenoma: report of a case investigated angiographically. PMID- 4313437 TI - Estrogen therapy and coronary artery disease: experimental studies in pigeons. PMID- 4313434 TI - A defect in pyruvate decarboxylase in a child with an intermittent movement disorder. AB - A patient with an intermittent movement disorder has been found to have an inherited defect in pyruvate decarboxylase ((2-oxo-acid carboxy-lyase, E.C. 4.1.1.1.). The patient is a 9 yr old boy who since infancy has had repeated episodes of a combined cerebellar and choreoathetoid movement disorder. He has an elevated level of pyruvic acid in his blood, an elevated urinary alanine content, and less marked elevations in blood alanine and lactate. Methods were developed to study his metabolic abnormality in dilute suspensions of white blood cells and cultured skin fibroblasts, as well as in cell-free sonicates of fibroblasts. Oxidation of pyruvic acid-1-(14)C and pyruvic acid-2-(14)C by his cells and pyruvate decarboxylase activity in sonicates of his cells were less than 20% of those in cells from control subjects. Oxidation of glutamic acid-U-(14)C, acetate 1-(14)C, and palmitate-1-(14)C was normal, as was incorporation of alanine-U (14)C into protein. The rate of oxidation of pyruvic acid by the father's cells and the activity of pyruvate decarboxylase in the father's sonicated fibroblasts were intermediate between those of the patient and those of controls. Values for the mother were at or just below the lower limits of the ranges in controls. Kinetic data suggested the posibility of several forms of pyruvate decarboxylase in this family. Possible mechanisms relating the chemical abnormality and the clinical symptoms in this patient are discussed. PMID- 4313438 TI - Clinical path conference. Uremia after Wilms's tumor therapy. PMID- 4313439 TI - Pregnancy tests. PMID- 4313440 TI - Perianal Paget's disease. PMID- 4313442 TI - The Narcotic Addict Rehabilitation Act: a change in the federal response to the treatment of narcotic addiction. PMID- 4313441 TI - [Adenoencephalitis in a service man. Case report]. PMID- 4313443 TI - Repair of the vagus. PMID- 4313444 TI - Euplotes eurystomus: histochemical identification of monamine oxidase, phosphomonoesterases, lipase and cytochrome oxidase. PMID- 4313445 TI - [Biochemical and clinical aspects of pyrophosphate metabolism. 2. Studies of the mechanism of enhanced pyrophosphate excretion in urine following orthophosphate loading]. PMID- 4313446 TI - Single and low dosage regimens of metronidazole in amoebic dysentery and amoebic liver abscess. PMID- 4313447 TI - Nitrogen dioxide inhibition of viral-induced resistance in alveolar monocytes. PMID- 4313448 TI - Use of nonimmersed in vitro chicken tracheal preparation for the study of ciliary transport activity. Cigarette smoke and related components. PMID- 4313449 TI - Mucus production and ciliary transport activity. In vivo studies using the chicken. PMID- 4313450 TI - Collagenase inhibitors in prevention of ulcers of alkali-burned cornea. PMID- 4313452 TI - Effects of adenosine compounds on renal function and renin secretion in dogs. PMID- 4313451 TI - Mycobacterium leprae in nerve lesions in lepromatous leprosy. An electron microscopic study. PMID- 4313453 TI - Pathogensis, diagnosis, and treatment of the tarsal-tunnel syndrome. PMID- 4313454 TI - Comparative sensitivity of two techniques of specimen inoculation for the isolation of viruses. PMID- 4313455 TI - [Solid tumor (embryonal abdominal carcinoma) clinically cured with only one dose of a cytostatic (Natulan). A new indication for ibenzmethyzin]. PMID- 4313456 TI - [Desmedt and decamethonium tests in the diagnosis of myasthenia gravis]. PMID- 4313457 TI - [Lipids composition of cytoplasmatic fractions from rat liver and Yoshida ascites hepatoma]. PMID- 4313458 TI - [Clinical aspects and neuropathology of trichloroethylene poisoning]. PMID- 4313459 TI - Pigmented villonodular synovitis of joints. Histological and clinical problems in diagnosis. PMID- 4313460 TI - Respiration of the cochlea and function. PMID- 4313461 TI - Supraspinal and segmental control of static and dynamic gamma-motoneurones in the cat. PMID- 4313463 TI - Effect of training on replicability of assessments of skeletal maturity (Greulich Pyle). PMID- 4313462 TI - Electron microscopic and histochemical observations on the supraoptic nucleus of normal and dehydrated rats. PMID- 4313464 TI - Massive calcification of the brain in a newborn infant. PMID- 4313465 TI - [Virologic study of fatal cases of poliomyelitic paralysis. I. Isolation of poliovirus in autoptic material]. PMID- 4313466 TI - Respiration-linked ATP formation by an "oxidative phosphorylation mutant" of yeast. PMID- 4313467 TI - Organization of the membrane-bound penicillinases of Bacillus licheniformis. PMID- 4313468 TI - Assays of glutamine and its aminotransferase with the enol-borate of phenylpyruvate. PMID- 4313469 TI - Incorporation of 5-iodo-2'-deoxyuridine-131-I into nuclear and mitochondrial DNA of normal and malignant mouse tissues. PMID- 4313470 TI - Redox potentials and phosphorylative efficiency of mitochondria. PMID- 4313472 TI - On the rate law and mechanism of the adenosine triphosphate--pyrophosphate isotope exchange reaction of amino acyl transfer ribonucleic acid synthetases. PMID- 4313471 TI - Equilibration of reducing equivalents among the terminal portions of the mitochondrial respiratory chains. PMID- 4313473 TI - Studies on an aged preparation of nucleoside diphosphatase. Kinetics and reaction mechanism. PMID- 4313474 TI - Alteration of the conformative response and inhibition of xanthosine 5'-phosphate aminase by adenine glycosides. PMID- 4313475 TI - Natural inhibitors of the transfer ribonucleic acid methylases. PMID- 4313476 TI - Primary and secondary effects of angiotensin on the coronary circulation. PMID- 4313477 TI - Lung scleroproteins in age and emphysema. PMID- 4313478 TI - [Study of prostatic carcinogenesis, using 20-methyl-cholanthrene in albino rats]. PMID- 4313479 TI - [Histotopochemical study of intestinal polyposis in connection with its cancerous evolution]. PMID- 4313480 TI - Morphologic findings in human cardiac allografts. PMID- 4313482 TI - The aged patient with a peripheral neuropathy. PMID- 4313481 TI - Electromyographic findings and conduction velocity on N-hexane polyneuropathy. PMID- 4313483 TI - The philosophy of stroke rehabilitation. PMID- 4313484 TI - [Hygienic assessment of working conditions in the wet process of mechanical working of glass and crystal]. PMID- 4313485 TI - Malignant mucocele of the appendix with thromboembolic manifestation. PMID- 4313487 TI - [Diagnosis of bronchial cancer]. PMID- 4313486 TI - [Modification of various forms of edema of the rat footpad by Trasylol]. PMID- 4313488 TI - [Eosinophilic pseudo-tumors of the stomach. Contribution on the differential diagnosis of gastric cancer]. PMID- 4313489 TI - Uremia: newer concepts in pathogenesis and treatment. PMID- 4313490 TI - Gout. PMID- 4313491 TI - Nutritional deficiencies in liver disease. PMID- 4313492 TI - Hypoglycemia: a complex problem. PMID- 4313493 TI - Aldosteronism in hypertensive disease. PMID- 4313494 TI - Collagenase: its physiological and pathological role. PMID- 4313496 TI - [D trisomy associated with diffuse cytomegalic inclusion disease]. PMID- 4313495 TI - Studies in glycogen storage disease. IV. Leukocyte phosphorylase in a family with type VI GSD. PMID- 4313497 TI - [On certain enzymatic changes in a case of methyl-salicylate acute poisoning]. PMID- 4313498 TI - Plasma insulin in disorders of carbohydrate metabolism. PMID- 4313499 TI - [Prognosis after surgical treatment of colonic cancer of the right side]. PMID- 4313500 TI - The requirement of capreomycin, ethambutol and rifampicin in chronic pulmonary tuberculosis in Helsinki on the basis of resistance indications. PMID- 4313501 TI - The onset of effect of ACTH, angiotensin II and raised plasma potassium concentration on the adrenal cortex. PMID- 4313502 TI - An electron paramagnetic resonance study of irradiated frozen aqueous sugar solutions. UCLA 12-724. PMID- 4313503 TI - [Procedure for the hemagglutionation test in myxovirus parainfluenzae 3]. PMID- 4313504 TI - Long term culture of normal and neoplastic human glia. PMID- 4313505 TI - Primary superficial carcinomas of the duodenum. PMID- 4313506 TI - Investigations on the enzymes and toxins of staphylococci. Study of phosphatase using p-nitrophenyl phosphate as substrate. PMID- 4313507 TI - Studies of Echovirus type 6 antigens in immunodiffusion. 2. Immunoelectrophoretic investigation. PMID- 4313508 TI - Studies of echovirus type 6 antigens in immunodiffusion. 3. Antibody response against echovirus 6 antigens in human infections with homologous and heterologous enteroviruses. PMID- 4313510 TI - Two cases of primary carcinoma of the liver in children. PMID- 4313509 TI - Effect of corticotrophin therapy on pituitary-adrenal function. PMID- 4313511 TI - [Transtemporal extralabyrinthine surgery of the internal auditory canal]. PMID- 4313512 TI - [Surgical technic in intratracheal glomus tumor of the upper thoracic part of the trachea]. PMID- 4313513 TI - [Hormone treatment of juvenile nasopharyngeal fibroma]. PMID- 4313514 TI - [Enzyme histochemical studies on the influence of ozothin on the ototoxic effect of streptomycin in guinea pigs]. PMID- 4313516 TI - Studies of herpes zoster virus in vitro. I. Isolation of two variants. PMID- 4313515 TI - [Influence of local pantocain application on enzymes of the cochlea and peripheral vestibular apparatus]. PMID- 4313517 TI - A highly branched alpha-D-glucan of Vibrio parahaemolyticus A55. I. Its isolation and structure. PMID- 4313518 TI - Plaque formation by three variants of the Miyama strain of herpes simplex virus. PMID- 4313519 TI - A comparative study of palmitoyl-CoA synthetase activity in rat-liver, heart and gut mitochondrial and microsomal preparations. PMID- 4313520 TI - The reduction of fungal laccase at high pH. PMID- 4313521 TI - Acetylene reduction with physiological electron donors by extracts and particulate fractions from nitrogen-fixing Azotobacter chroococcum. PMID- 4313522 TI - Further studies on the NADH oxidase of the cytoplasmic membrane of Mycobacterium tuberculosis. PMID- 4313523 TI - Light- and chemically-induced oxidation-reduction reactions in chromatophore fractions of Rhodospirillum rubrum. PMID- 4313525 TI - Chloroplast inorganic pyrophosphatase. PMID- 4313524 TI - Occurrence of both a-type and o-type cytochromes as the functional terminal oxidases in Rhodopseudomonas spheroides. PMID- 4313526 TI - The electron transport systems of heart muscle and yeast: site of inhibition by chloramphenicol. PMID- 4313527 TI - Solubilization and properties of the hydrogenase of Chromatium. PMID- 4313528 TI - Purification and properties of Drosophila malate dehydrogenases. PMID- 4313529 TI - Structural studies on the active center of alpha-glycerolphosphate dehydrogenase. PMID- 4313530 TI - The effect of NAD+ on the catalytic efficiency of glyceraldehyde-3-phosphate dehydrogenase from rabbit muscle. PMID- 4313531 TI - Structure-function studies on glyceraldehyde-3-phosphate dehydrogenase. II. The effects of S-carboxymethylation on enzymatic activity. PMID- 4313532 TI - Purification of aminopeptidase A in human serum and degradation of angiotensin II by the purified enzyme. PMID- 4313533 TI - Application of a rapid colorimetric assay to detect alterations in rat proline imino peptidase. PMID- 4313534 TI - Separation of collagenase and peptidase activities of tadpole tissues in culture. PMID- 4313535 TI - Aspects of the kinetic properties of lysyl-tRNA synthetase from Escherichia coli, strain B. PMID- 4313536 TI - Evidence of a specific copper(II) in human ceruloplasmin as a binding site for inhibitory anions. PMID- 4313537 TI - [A case of cerebellar glioma in the aged]. PMID- 4313539 TI - The conversion of [35S] PTC-angiotensin I to PTC-angiotensin II in plasma of normotensive and hypertensive subjects. PMID- 4313538 TI - Studies with angiotensins I and II; the use of phenylthiocarbamyl-derivatives. PMID- 4313540 TI - Angiotensin blood levels during the evolution of acute renal failure. PMID- 4313541 TI - Heterokaryon formation between alkaline phosphatase variants in a human heteroploid cell line. PMID- 4313542 TI - [Attempt to isolate viruses from aphthous, herpetiform and herpetic ulcerations]. PMID- 4313543 TI - [On the relations between Entamoeba histolytica, Laredo strains, Entamoeba invadens and Entamoeba moshkovskii evaluated according to their sensitivity to anti-amebic drugs]. PMID- 4313544 TI - [Effect of CCl4 on oxidoreductase and phosphatase enzyme activity in the liver of albino rats (histochemical study)]. PMID- 4313546 TI - [Antibody complement fixation for respiratory syncytial virus and adenovirus and hemagglutination inhibition of para-influenza viruses 1, 2 and 3 in a Brazilian children population]. PMID- 4313547 TI - [Isolation and subtype identification of poliovirus strains following the administration of Sabin vaccine]. PMID- 4313548 TI - [Effect of hypoxia on the activity of some nicotinamide-adenine dinucleotide enzymes]. PMID- 4313545 TI - Hypercalcemia and increased parathyroid-hormone activity in a primary hepatoma. Studies before and after hepatic transplantation. PMID- 4313549 TI - [Radioisotope diagnosis of breast neoplasms]. PMID- 4313550 TI - [A method of obtaining chicken serum immune to Rous virus]. PMID- 4313551 TI - [The morphogenesis of muco- and cartilage-like structures in so-called mixed salivary gland tumors]. PMID- 4313552 TI - [Explanation of benign giant cell synoviomas]. PMID- 4313553 TI - [The importance of the spleen in the pathogenesis of murine virus induced leukemias]. PMID- 4313554 TI - [Combined use of biological preparations for emergency prevention of cholera (experimental data)]. PMID- 4313555 TI - Viruses, Mycoplasma pneumoniae and bacteria associated with lower respiratory tract disease among infants. PMID- 4313556 TI - Ecologic studies of vesicular stomatitis virus. II. Results of experimental infection in Panamanian wild animals. PMID- 4313557 TI - Islet-cell adenoma of the pancreas with reversible watery diarrhea and hypokalemia. WDHA syndrome. PMID- 4313558 TI - Dysimmunoglobulinemia associated with hepatobiliary disorders. PMID- 4313559 TI - Interrelationships of renin and aldosterone in a patient with hypoaldosteronism. PMID- 4313560 TI - Disease patterns and vaccine-response studies in isolated Micronesian populations. PMID- 4313561 TI - Studies of arthropod-borne virus infections in chiroptera. VI. Isolation of Japanese B encephalitis virus from naturally infected bats. PMID- 4313562 TI - Studies of arthropod-borne virus infections in chiroptera. VII. Serologic evidence of natural Japanese B encephalitis virus infection in bats. PMID- 4313563 TI - Broadening spectrum of Herpesvirus hominis (Herpes simplex). PMID- 4313564 TI - A new device for monitoring force of thumb adduction. PMID- 4313565 TI - A new theory of the action of muscle relaxants. PMID- 4313568 TI - Scanning and transmission electron microscopic observations of the topographic anatomy of dendritic lesions in the rabbit cornea. PMID- 4313566 TI - Fatal Japanese encephalitis virus infection in immunosuppresed spider monkeys. PMID- 4313567 TI - Spin transfer in gamma-irradiated nucleotide complexes. PMID- 4313569 TI - Endothelial lesions of rabbit cornea produced by herpes simplex virus. PMID- 4313570 TI - Isolation of a Golgi apparatus-rich fraction from rat liver. II. Enzymatic characterization and comparison with other cell fractions. AB - Enzymatic activities associated with Golgi apparatus-, endoplasmic reticulum-, plasma membrane-, mitochondria-, and microbody-rich cell fractions isolated from rat liver were determined and used as a basis for estimating fraction purity. Succinic dehydrogenase and cytochrome oxidase (mitochondria) activities were low in the Golgi apparatus-rich fraction. On the basis of glucose-6-phosphatase (endoplasmic reticulum) and 5'-nucleotidase (plasma membrane) activities, the Golgi apparatus-rich fraction obtained directly from sucrose gradients was estimated to contain no more than 10% endoplasmic reticulum- and 11% plasma membrane-derived material. Total protein contribution of endoplasmic reticulum, mitochondria, plasma membrane, microbodies (uric acid oxidase), and lysosomes (acid phosphatase) to the Golgi apparatus-rich fraction was estimated to be no more than 20-30% and decreased to less than 10% with further washing. The results show that purified Golgi apparatus fractions isolated routinely may exceed 80% Golgi apparatus-derived material. Nucleoside di- and triphosphatase activities were enriched 2-3-fold in the Golgi apparatus fraction relative to the total homogenate, and of a total of more than 25 enzyme-substrate combinations reported, only thiamine pyrophosphatase showed a significantly greater enrichment. PMID- 4313571 TI - Gas gangrene: the spectre still looms. PMID- 4313572 TI - Chemical and biological properties of the purified O antigen of Bordetella pertussis. PMID- 4313573 TI - Production of pathogen free avian cell substrate for production of vaccines. PMID- 4313574 TI - Management of chemodectomas (glomus jugulare). PMID- 4313575 TI - [Midpoint oxidation-reduction potentials of cytochrome oxidase from bovine heart muscle]. PMID- 4313576 TI - Association of a [corrected] murine leukaemia virus from a mouse lymphoma (2731 L) associated [corrected] with reovirus type 3 infection. PMID- 4313577 TI - Surface leukaemic antigen and malignancy of cells in mice infected with Mazurenko virus. PMID- 4313578 TI - Bridging the gap in continuity of care. PMID- 4313581 TI - Paradoxical sleep in two species of avian predator (Falconiformes). AB - Periods of disconjugate. and conjugate eye movements occur during the sleep cycle in Buteo jamaicensis arborealis and Herpetotheres cachinnans chapmanni. Electromyograms are essentially isoelectric throughout sleep. Slow waves appear only in short bursts of low amplitude in contrast to the long trains of high amplitude waves reported for chickens and pigeons. PMID- 4313580 TI - Pineal gland: dibutyryl cyclic adenosine monophosphate stimulation of labeled melatonin production. AB - In organ cultures of intact rat pineal glands, N(6)O(2')-dibutyryl adenosine 3', 5'-monophosphate stimulates the conversion of tritiated trytophan to tritiated melatonin, as does L-norepinephrine. Potential sites of stimulation of melatonin production by dibutyryl cyclic adenosine monophosphate are discussed, based on observations that the dibutyryl analog also stimulates the conversion of serotonin labeled with carbon-14 to carbon-14-labeled melatonin without altering hydroxyin-dole-O-methyl transferase activity or intracellular accumulation of serotonin labeled with carbon-14. PMID- 4313579 TI - Effects of carbon dioxide, bicarbonate and pH on lactate and pyruvate in the brain of rats. PMID- 4313582 TI - Transplantation antigen program. ORNL-4419. PMID- 4313583 TI - [Study of 100 cases of cirrhosis in Brussels. II. Morphologic study and discussion of the validity of histologic classification of cirrhosis]. PMID- 4313584 TI - [Cytochemical study of SIRC cells infected with the rubella virus]. PMID- 4313585 TI - Antigenic characterization of poliovirus strains isolated in Italy (1964-1968) from vaccinated and unvaccinated patients. PMID- 4313586 TI - Continuous monitoring of blood glucose during operation for islet cell adenomas. PMID- 4313587 TI - [Synaptic processes in motor neurons in the course of viscero-somatic reflexes]. PMID- 4313588 TI - [The antigenic properties of DNA entering into the composition of an artificial DNA-protein complex]. PMID- 4313589 TI - [Induced pulmonary adenomatosis in rabbits]. PMID- 4313591 TI - Presence of particles other than the Australia-SH antigen in a case of chronic active hepatitis with cirrhosis. AB - Examination of serum specimens from a patient with chronic active hepatitis proved negative to the Australia-SH antigen by immunodiffusion and by complement fixation. Because the sera were anticomplementary they were examined with the electron microscope, and virus-like structures similar to members of the coronavirus group were identified. The possible significance of this finding in human serum and its relation to mouse hepatitis virus are discussed.A sample of the serum pool containing the MS-1 agent was found negative when examined by immunodiffusion, complement fixation, and electron microscopy. The possible lack of immunological identity between infectious and serum hepatitis is discussed. PMID- 4313592 TI - Clinical and endocrine side-effects of methylprednisolone acetate as used in hay fever. AB - Eight patients were treated with two 80-mg. doses of methylprednisolone acetate (Depo-Medrone), given at an interval of two weeks. Pituitary-adrenal function was assessed before, during, and after treatment.Plasma cortisol levels were depressed maximally 72 hours after each injection of methylprednisolone acetate, and then gradually returned to normal. The adrenocortical response to administered corticotrophin was similarly affected; in seven patients normal values were again recorded three weeks after the second injection of methylprednisolone acetate. One patient whose adrenal function had returned to normal still showed some degree of pituitary suppression eight weeks after his second injection. Several side-effects were noted, and clinically the patients fared less well than a larger series studied during the previous year. PMID- 4313593 TI - A case of endocrine dysfunction with lung carcinoma. PMID- 4313590 TI - Renin and acute renal failure: studies in man. AB - Plasma renin concentration was increased, usually appreciably, in 22 out of 25 patients with acute renal failure, the average value being 226 units/litre (mean for normal subjects 8.2 units/1.). The highest renin values were found in the first 10 days of the disease; lower and sometimes normal values were found subsequently. Unequivocal acute tubular necrosis was present in only two of the eight cases examined post mortem.These findings are compatible with Goormaghtigh's proposal that an excess of renin and angiotensin may act within the kidney to produce acute renal failure. PMID- 4313594 TI - [Chromatographic separation and identification of 3-hydroxy,4-methoxymandelic (iso-VMa) and 4-hydroxy,3-methoxymandelic (VMA) acids in the form of their periodic oxidation derivatives: isovanillin and vanillin. Presence of 3-hydroxy,4 methoxymandelic acid in human urine]. PMID- 4313595 TI - [Structures and activities of polynucleotide phosphorylases]. PMID- 4313596 TI - [Distribution of pyrimidine oligonucleotides in Herpesvirus hominis DNA and in host cells (fetal lamb kidney)]. PMID- 4313597 TI - [Effect of premarin tablets and intravenous injection of premarin on functional uterine bleeding]. PMID- 4313598 TI - Antilipolysis as a tool in the study of clinical and experimental diabetes. Lecture for the 1968 Minkowski Award. PMID- 4313599 TI - An analysis of the lipolysis in vitro of obese-hyperglycaemic and diabetic mice. PMID- 4313601 TI - [On a case of encephalomyocarditis]. PMID- 4313600 TI - [Behavior of certain biologic indices in virus diseases]. PMID- 4313602 TI - The mode of action of antifungal agents: effect of pyrrolnitrin on mitochondrial electron transport. PMID- 4313604 TI - Enzymatic alkylenation of phospholipid fatty acid chains by extracts of Mycobacterium phlei. PMID- 4313603 TI - Isolation and crystallization of acyl phosphatase from rabbit muscle. PMID- 4313605 TI - Evidence for a functional change in the plasma membrane of murine sarcoma virus infected mouse embryo cells. Transport and transport-associated phosphorylation of 14C-2-deoxy-D-glucose. PMID- 4313606 TI - Adenyl cyclase in fat cells. 3. Stimulation by secretin and the effects of trypsin on the receptors for lipolytic hormones. PMID- 4313607 TI - Azotobacter vinelandii ribonucleic acid polymerase. IX. Alternating copolymer of inosinic and cytidylic residues-directed synthesis of alternating copolymer of guanylic and cytidylic residues. PMID- 4313609 TI - Physical and chemical studies on ceruloplasmin. 8. Preparation of N acetylneuraminic acid-1-14C-labeled ceruloplasmin. PMID- 4313608 TI - Azotobacter vinelandii ribonucleic acid polymerase. X. Some physical properties of the alternating copolymers of inosinic and cytidylic residues and of guanylic and cytidylic acid residues. PMID- 4313610 TI - The regulation of gluconeogenesis. The effect of pent-4-enoic acid on gluconeogenesis and on the gluconeogenic metabolite concentrations of isolated perfused rat liver. PMID- 4313611 TI - The formation of a ternary complex between diphtheria toxin, aminoacyltransferase II, and diphosphopyridine nucleotide. PMID- 4313612 TI - Electron paramagnetic resonance studies on iron-sulfur proteins of submitochondrial particles from Candida utilis cells. PMID- 4313613 TI - On the nature of the latency relaxation of frog skeletal muscle. PMID- 4313615 TI - Collagen resorption in carrageenin granulomas. II. Ultrastructure of collagen resorption. PMID- 4313614 TI - Collagen resorption in carrageenin granulomas. I. Collagenolytic activity in in vitro explants. PMID- 4313616 TI - [Diagnosis of malignant tumors of the stomach using P32]. PMID- 4313617 TI - [The practical significance of diagnosing stomach cancer by means of P32]. PMID- 4313618 TI - [Radiotherapy of diseases of the peripheral nervous system]. PMID- 4313620 TI - Arrhenoblastoma in first cousins. Report of 2 cases. PMID- 4313619 TI - Lactate dehydrogenase isoenzymes and proteins in human gliomas. PMID- 4313621 TI - Clostridial organisms in septic abortions. Report of 7 cases. PMID- 4313622 TI - Malignant mixed mullerian tumors of the uterine corpus. PMID- 4313624 TI - Synovial sarcoma and its treatment. PMID- 4313625 TI - [A case of Abrikosov tumor of the larynx]. PMID- 4313623 TI - Biochemical approach to a tumor localizing agent: 51Cr-beta-glycerophosphate complex. PMID- 4313627 TI - [Relationship among physiological indices during sleep and characteristics of dreams--a psychophysiological study on dreams in normal human subjects (II)]. PMID- 4313626 TI - Endolymphatic radiotherapy (ERT) for malignant lymphomas: indications and long term results. PMID- 4313628 TI - [Hemarthrosis in gonarthrosis]. PMID- 4313629 TI - [Suicide and paraplegia]. PMID- 4313630 TI - [Morvan's analgesic panaris and ulcero-mutilating acropathy]. PMID- 4313631 TI - [Migraine and hepato-biliary-digestive system]. PMID- 4313632 TI - [Infections due to "Salmonella Typhi murium" transmitted in pork]. PMID- 4313634 TI - [Content of free 17-oxycorticosteroids in the blood of patients with scleroderma]. PMID- 4313633 TI - Reactivatability of soman-inhibited end plate cholinesterase and neuromuscular transmission. PMID- 4313635 TI - Sendai virus infection of rats as a convenient model of acute respiratory infection. PMID- 4313636 TI - [Contrasting the thoracic duct and distal lymph nodes in lower lymphography]. PMID- 4313638 TI - [The susceptibility of humans to Herpesvirus suis (Aujeszky-virus). II. Antigenetic relations between Herpesvirus suis and Herpesvirus simplex]. PMID- 4313637 TI - [Lines of transplantable cells transformed by SV40 virus in tissue culture]. PMID- 4313639 TI - [The susceptibility of humans to Herpesvirus suis (Aujeszky-virus). 3. Studies on the possible involvement of the virus in abortions]. PMID- 4313640 TI - [Unilateral papilledemas]. PMID- 4313641 TI - [Association of eosinophilic pituitary adenoma with malignant neoplasms of nonneural origin]. PMID- 4313642 TI - [Problems in the management of childhood elbow fractures complicated by nerve injury]. PMID- 4313643 TI - Exfoliative cytopathology of a primary pulmonary malignant histiocytoma. PMID- 4313644 TI - [A case of mixed tumor of the sweat glands]. PMID- 4313645 TI - [Current treatment of Paget's disease of the nipples and mammary area]. PMID- 4313646 TI - Aeromonas and serratia. Comparative study of extracellular deoxyribonuclease production and other biochemical characteristics. PMID- 4313647 TI - Fibrosarcoma of the chest wall following resection and irradiation of carcinoma of the breast. PMID- 4313648 TI - [Intramural myoid tumors of the stomach]. PMID- 4313649 TI - Peripheral neuropathy. PMID- 4313650 TI - [Inactivation of poliomyelitis virus by ultraviolet rays using a series apparatus. Comparison with bacteriologic results]. PMID- 4313651 TI - Granular cell myoblastoma. PMID- 4313652 TI - Histologic classification of liver-cell carcinoma in infancy and childhood and its clinical evaluation. A study of 70 cases collected in Japan. PMID- 4313653 TI - A melanotic ovarian neoplasm resembling the "retinal anlage" tumor. PMID- 4313654 TI - Clear cells of the nipple epidermis. PMID- 4313655 TI - The lipid composition of mitochondrial and microsomal fractions of rat myocardial homogenates. PMID- 4313656 TI - Cardiovascular effects of angiotensin mediated by the central nervous system of the rabbit. PMID- 4313657 TI - Effects of exogenous adenosine 3',5'-monophosphate in man. 3. Increased response and tolerance to the dibutyryl derivative. PMID- 4313658 TI - Medical grand rounds at Yale-New Haven Hospital. Diagnosis and management of hypoglycemia. PMID- 4313659 TI - Clinical evaluation of complement-fixation-reaction and hemagglutination inhibition-test in measles of MS patients. PMID- 4313660 TI - Myxoviruses and multiple sclerosis. PMID- 4313661 TI - The role of host-incorporated antigens in the immune response to measles virus. PMID- 4313662 TI - Host-specific antigens of lipid-containing RNA-viruses. Viruses as a carrier of cell-specific antigens. PMID- 4313664 TI - Possible mechanism of adjuvant action. PMID- 4313665 TI - Cytologic ultrastructural considerations and studies of the pathogenesis of demyelinating processes. PMID- 4313666 TI - Clinical problems of acute necrotizing encephalitis. PMID- 4313663 TI - Chronic viral neuropathies: models for study and food for thought. PMID- 4313667 TI - The comparative study of acute or subacute necrotizing encephalitis in humans to experimental herpes simplex encephalo-myelo-neuritis in newborn to adult mice using fluorescent antibody method. PMID- 4313668 TI - Ultrastructural studies in progressive multifocal leukoencephalopathy, a demyelinating disease of man of probable viral etiology. PMID- 4313669 TI - Quantitative determination of phospholipids in small tissue samples. PMID- 4313670 TI - Ultrastructure of the mammalian adrenal cortex. PMID- 4313671 TI - Effect of adenosine 5'-triphosphate and nicotinamide adenine dinucleotide on oxidative phosphorylation of aged brain mitochondria. PMID- 4313672 TI - [A recent case of combined scleroderma and lung alveolar cancer]. PMID- 4313674 TI - A cookbook of anti-cancer chemotherapy for solid tumors. PMID- 4313673 TI - Transfer of inorganic phosphate across human erythrocyte membranes. PMID- 4313675 TI - The release of H3-norepinephrine in arterial strips studied by the technique of superfusion and transmural stimulation. PMID- 4313676 TI - [Isolation and characterization of a strain of infectious bovine rhinotracheitis virus]. PMID- 4313677 TI - [The effect of pituitary and adrenal cortex hormones on leucocytolysis and phagocytosis]. PMID- 4313678 TI - [The clinical aspects of cylindroma. Problem of malignancy or semimalignancy of cylindromatous tumors]. PMID- 4313679 TI - [Transmission of information of hunger and thirst and its control]. PMID- 4313680 TI - [Lipid metabolism and interrelationship of organs, with special emphasis on neutral fat metabolism]. PMID- 4313681 TI - [Maintenance of blood pressure, with special reference to renin-angiotensin system]. PMID- 4313682 TI - [Thyroid hormone and catecholamines]. PMID- 4313683 TI - [Wilms' tumor. Survival]. PMID- 4313684 TI - Sleep stage characteristics of long and short sleepers. AB - The possibility of different sleep stage characteristics being associated with different sleep lengths was explored by comparing two groups of high school seniors, who characteristically slept 6(1/2) hours or less or who slept 8(1/2) hours or more, with an age-matched control group not selected on the basis of sleep length. All-night electroencephalography was used to examine the sleep stage characteristics of these groups. Compared with the unselected age-matched group, the short sleepers showed no significant diminution in their stage 4 (deep) or rapid eye movement (dream) sleep. The long sleepers were observed to obtain significantly more rapid eye movement sleep than did the other groups. PMID- 4313685 TI - [Histochemical studies of cytochromoxidase activity in the gastric mucosa of patients with iron deficiency anemia]. PMID- 4313686 TI - [Effect of glucocorticoid therapy on the clinical-biochemical morphological and histochemical data in patients with postnecrotic liver cirrhosis]. PMID- 4313688 TI - [Reconstruction of the interdigital space in syndactylia]. PMID- 4313687 TI - [Changes of Wilms tumor following radium therapy]. PMID- 4313689 TI - [Clinical use of synthetic corticotropin in allergy]. PMID- 4313690 TI - [Angiography of the hepatic scintigraphic lacuna]. PMID- 4313691 TI - [Progress in dermatologic therapy]. PMID- 4313692 TI - The intramitochondrial distribution of some enzymes involved in the biosynthesis of rat-liver phospholipids. PMID- 4313693 TI - Incorporation of 33P in soybean phosphatides. PMID- 4313694 TI - Lipid composition of isolated rat-thymus nuclei. PMID- 4313695 TI - On the occurrence of sphinga-4, 8-dienine in oyster glycolipid. PMID- 4313696 TI - Lipid metabolism in bone and bone cells. I. The in vitro incorporation of [14C] glycerol and [14C] glucose into lipids of bone and bone cell cultures. PMID- 4313697 TI - The effects of pyridine nucleotides and glycerol on lipid phosphorylation in rat liver mitochondria. PMID- 4313698 TI - [Neurophysiological mechanisms of delayed responses]. PMID- 4313699 TI - The effect of chain length on the phosphorolysis of oligonucleotides by polynucleotide phosphorylase. PMID- 4313700 TI - The mechanism of action of sucrose phosphorylase. Isolation and properties of a beta-linked covalent glucose-enzyme complex. PMID- 4313701 TI - An examination of the zinc requirement for the catalytic activity of 3 phosphoglyceraldehyde dehydrogenase. PMID- 4313702 TI - An essential histidine in the catalytic activities of 3-phosphoglyceraldehyde dehydrogenase. PMID- 4313703 TI - Stimulation by growth hormone and dexamethasone of labeled cyclic adenosine 3',5' monophosphate accumulation by white fat cells. PMID- 4313705 TI - Regulatory characteristics of the diphosphopyridine nucleotide-specific malic enzyme of Escherichia coli. PMID- 4313704 TI - Evidence for the biologically active form of cholecalciferol in the intestine. PMID- 4313707 TI - Kinetic analysis of the phosphorolysis of oligonucleotides by polynucleotide phosphorylase. PMID- 4313708 TI - Ribonucleic acid content of encephalomyocarditis virus. PMID- 4313706 TI - Adenyl cyclase in cardiac tissue. PMID- 4313709 TI - Particle weight and other biophysical properties of encephalomyocarditis virus. PMID- 4313710 TI - Target molecular weight of foot-and-mouth disease virus and poliovirus. PMID- 4313712 TI - [Cross-striped fibrils in Schwann cells]. PMID- 4313711 TI - [Adrenal cortex function in patients with burns]. PMID- 4313713 TI - [Cholangiomatous mucopolysaccharidosis and cholangioma formation in nitrosamine poisoned rats]. PMID- 4313714 TI - Interactions of angiotensin and cocaine on the output of noradrenaline from isolated rabbit hearts. PMID- 4313715 TI - Synergism between phospholipase A and various peptides and SH-reagents in causing haemolysis. PMID- 4313716 TI - [Acute leukemia in pregnancy terminated in generalized cytomegaly]. PMID- 4313717 TI - [Retinal anlage tumor in 10-month-old child]. PMID- 4313718 TI - Effects of sodium transport stimulating substances on enzyme activities in the toad bladder. PMID- 4313719 TI - Cytotropism of leukemia viruses. PMID- 4313720 TI - A respiratory virus study in Great Britain: review and evaluation. PMID- 4313721 TI - Organ cultures in virology. PMID- 4313722 TI - [Magnesium]. PMID- 4313723 TI - [The relation of angiotensin and aldosterone to renal functions and to the mineral household]. PMID- 4313724 TI - [Steroid therapy and its effect on the functional state of the hypophyseal adrenal system in nonspecific ulcerative colitis]. PMID- 4313725 TI - [The mutual effects of scleroderma diffusum and pregnancy]. PMID- 4313726 TI - [Mechanism of neuromuscular transmission in insects. Effects of tubocurarine chloride and flaxedil (gallamine)]. PMID- 4313727 TI - Plasma metyrapone, adrenocorticotropic hormone, cortisol, and deoxycortisol levels. Sequential changes during oral and intravenous metyrapone administration. PMID- 4313728 TI - Single-dose metyrapone test. PMID- 4313729 TI - Cytomegalovirus infection associated with cardiopulmonary bypass. PMID- 4313730 TI - [Significance of cytomegaly in early childhood patology]. PMID- 4313731 TI - [Pathomorphologic characteristics of cytomegaly]. PMID- 4313732 TI - [Lesions of the brain in cytomegaly]. PMID- 4313733 TI - Hormonal imbalance and the sarcomata. PMID- 4313734 TI - Quantitative dissolution of the membrane and preparation of photoreceptor subunits from Rhodopseudomonas spheroides. PMID- 4313735 TI - Amino acid sequence of cyanogen bromide peptides from the amino-terminal region of chick skicollagen. PMID- 4313736 TI - Ring-opening reaction of 1-(N,N-dimethylcarbamoyl)pyridinium chloride with hydroxide. A model for the alkaline diphosphopyridine nucleotide reaction. PMID- 4313738 TI - Nucleotide pool levels in growing, inhibited, and transformed chick fibroblast cells. PMID- 4313737 TI - Structure of the glycopeptide from bovine visual pigment 500. PMID- 4313739 TI - Further purification and properties of phosphodiesterase from the carrot. PMID- 4313740 TI - Relation of reactivity to structure in pancreatic ribonuclease. I. An analysis of the various reactions with bromoacetate in the pH range 2-7. PMID- 4313741 TI - Relations of reactivity to structure in pancreatic ribonuclease. II. Positions of residues alkylated in certain conditions by bromoacetate. PMID- 4313742 TI - Phosphofructokinase and glycolysis in the livers of rats fed a thrombogenic diet. PMID- 4313744 TI - Potentiation of excitatory junctional potentials and glutamate-induced responses in crayfish muscle by 5'-ribonucleotides. PMID- 4313743 TI - Quantitation of plasma testosterone by improved competitive protein-binding technique. PMID- 4313745 TI - In vitro action of calcium ions on the interrenal corticosteroidogenesis of the eel (Anguilla anguilla L.). PMID- 4313748 TI - Enhancement of haemagglutinin production in polyoma virus-infected Candida by a defined medium and urethan. PMID- 4313747 TI - The inhibitory effect of sodium on the contraction of frog's heart perfused with sucrose solution. PMID- 4313746 TI - Developments in the field of vitamins. PMID- 4313749 TI - Experimental brain tumours in dogs. PMID- 4313750 TI - [Inhibition of reflex responses at the level of segmentary internuncial neurons]. PMID- 4313751 TI - [Analysis of fatigue by short-term tetanization at various frequency of isolated frog skeletal muscle]. PMID- 4313752 TI - The fine structure of equine papillomas and the equine papilloma virus. PMID- 4313753 TI - [Peculiarities of the treatment of malignant neoplasms in children]. PMID- 4313754 TI - [Primary hepatic cancer and polyglobulism: review of literature and presentation of a personal case]. PMID- 4313755 TI - [Renin, angiotensin, aldosterone and arterial hypertension. II]. PMID- 4313756 TI - [Follicular conjunctivitis]. PMID- 4313757 TI - [Insulinoma of the pancreas]. PMID- 4313758 TI - [Histophysiology of neurosecretory elements of the neurohypophysis and adrenocorticotropic function in audiogenic "reflex" epilepsy]. PMID- 4313759 TI - [Clinical forms of peripheral nervous system involvement in diabetes mellitus]. PMID- 4313760 TI - Chemotherapy of chlamydial infections. PMID- 4313761 TI - Drugs and the mechanism of insulin secretion. PMID- 4313762 TI - [A study of the mechanism of induction of SV40 virus development in transformed Syrian hamster cells. II. Kinetics of virion production]. PMID- 4313763 TI - [Immunofluorescent study of the kinetics of the foot-and-mouth disease virus on cell cultures]. PMID- 4313764 TI - In vitro effects of carbenicillin combined with gentamicin or polymyxin B against Pseudomonas aeruginosa. AB - Disodium carbenicillin and gentamicin sulfate have both shown promise in the treatment of infections caused by Pseudomonas aeruginosa. This study was designed to explore possible synergistic relationships among the new as well as the established antimicrobial agents used to treat such infections. With an agar dilution technique, minimum inhibitory concentrations of 27 strains of P. aeruginosa were determined in two-dimensional tests. Graphs of equal biological activity (isobolograms) demonstrated moderate synergistic effects of the carbenicillin-gentamicin combination over therapeutically feasible concentration ranges. In contrast, the combination of carbenicillin and polymyxin B showed only additive or slightly antagonistic effects. Tests of bacterial killing confirmed the presence of carbenicillin-gentamicin synergy in 3 of 6 strains of P. aeruginosa, but did not show true antagonism between carbenicillin and polymyxin B. Clinical trials of both drug combinations are advisable to determine whether therapeutic results can be improved, and whether the dosages of gentamicin or polymyxin B can thereby be reduced to lessen their toxic hazards. PMID- 4313765 TI - Enzymes produced by a Pseudomonas species which inactivate inhibitors of certain viral hemagglutinins. I. Identification and purification of a proteinase and phospholipase C. AB - Filtrates from cultures of a psychrophilic Pseudomonas species, which inactivate serum inhibitors of certain viral hemagglutinins, were shown to contain both lecithinase (phospholipase C) and a proteolytic enzyme with elastase activity. The bacterium was cultivated under conditions favoring production of the respective enzymes, and the enzymes were purified by ammonium sulfate precipitation followed by column chromatography or by gel filtration. The elastase was obtained in crystalline form and was recrystallized. It has properties similar to those of a number of other bacterial elastases but is more heat-labile than most. Although a high degree of purification was achieved for the lecithinase, as evidenced by an increase in specific activity, it was not obtained in crystalline form. Partially purified preparations of the lecithinase had extremely high activity compared to that of commercial preparations of phospholipase C from Clostridium welchii. PMID- 4313766 TI - Isolation of human enterovirus from mussels. AB - Mussels maintained in sea water heavily polluted with domestic raw sewage have been found to harbor human enteroviruses. PMID- 4313767 TI - Accumulation of oxidized diphosphopyridine nucleotide in mouse liver after administration of reduced diphosphopyridine nucleotide. PMID- 4313768 TI - CO as a ligand of photosensitive P-630 transformed from horseradish peroxidase in the presence of indole-3-acetic acid. PMID- 4313770 TI - Exercise deprivation. Sleep and psychological reactions. PMID- 4313769 TI - Biogenesis of mitochondria. 12. The effects of aminoglycoside antibiotics on the mitochondrial and cytoplasmic protein-synthesizing systems of Saccharomyces cerevisiae. PMID- 4313771 TI - Bactericidal action of selected phenanthroline chelates and related compounds. PMID- 4313772 TI - Preparation of a stable noninfective diagnostic antigen for herpes simplex prepared from chick embryo tissue cultures. PMID- 4313773 TI - Wilms' tumor in children. Case histories. PMID- 4313775 TI - Ultrastructural data in cases of necrotizing encephalitis without inclusion bodies. PMID- 4313774 TI - Denervation myotonia: a subclinical electromyographic finding. PMID- 4313776 TI - The environment and function of invertebrate nerve cells. PMID- 4313777 TI - Verbally induced behavioral responses during sleep. PMID- 4313778 TI - Effects of sleep state and method of awakening upon thematic apperception test productions at arousal. PMID- 4313779 TI - Different effect of an auditory stimulus as a function of rapid eye movement and non-rapid eye movement sleep. PMID- 4313780 TI - Digital computer analysis of the electroencephalogram during rapid eye movement sleep state in man. PMID- 4313781 TI - Correlates of home dream recall. I. REM sleep in the laboratory as a predictor of home dream recall. PMID- 4313782 TI - Clinicopathologic conference. Baptist Memorial Hospital. Brain stem glioma in children. PMID- 4313783 TI - Herpesvirus infection in burned patients. PMID- 4313784 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 13-1970. PMID- 4313785 TI - Leukemia, drugs and ACTH. PMID- 4313786 TI - Leukemia, drugs and ACTH. PMID- 4313787 TI - Turban tumors. Endothelioma capitis. PMID- 4313788 TI - [Electron microscopic studies on the SV 40 development in kidney cells of Erythrocebus patas]. PMID- 4313789 TI - Cushing's disease as a psychosomatic disorder: a selective review of the clinical and experimental literature and a report of ten cases. PMID- 4313790 TI - [Present anatomo-pathologic aspects of lung cancer]. PMID- 4313791 TI - Further studies of avian osteopetrosis virus. 2. Communication. PMID- 4313792 TI - Agglutinins in chickens infected with JM leukosis virus. PMID- 4313793 TI - Regional ileitis or carcinoma. PMID- 4313794 TI - [Modification of hormone action, with special reference to interaction among pituitary, pancreatic and adrenocortical hormones]. PMID- 4313795 TI - Histochemical and histo-enzyological investigations of growing cartilage in pseudohypoparathyroidism. PMID- 4313797 TI - Subcellular distributin and arterio-venous differences of synthetic 3H-beta-1-23 corticotrophin-23-amide-acetate in the adrenal of rats. PMID- 4313798 TI - Glucose-6-phosphatase in human endometrium. PMID- 4313796 TI - The plasma 11-hydroxycorticosteroids responseto insulin-induced hypoglycaemia in children and adolescents. PMID- 4313799 TI - [Excretion rates after Sabin oral vaccination against poliomyelitis in Tyrol]. PMID- 4313801 TI - The actions of ethinyloestradiol on the pituitary-adrenal system of the rat. PMID- 4313800 TI - The pharmacology of ambenoxan (2-(3',6'-dioxaheptyl)-aminomethyl-1:4 benzodioxane), a centrally acting muscle relaxant. AB - 1. The intravenous, subcutaneous and oral toxicity of ambenoxan in mice is reported.2. Ambenoxan is a centrally acting skeletal muscle relaxant shown to be effective in mice, rats, rabbits, dogs and monkeys without loss of the righting reflex.3. It had no peripheral neuromuscular blocking properties.4. Decerebrate rigidity was depressed or abolished in the rabbit.5. The effects of strychnine, leptazol, or tremorine were not antagonized.6. In common with other depressants of the central nervous system, ambenoxan prolonged the sleeping time of hexobarbitone.7. Ambenoxan had no local anaesthetic properties.8. In the anaesthetized cat the drug lowered the blood pressure and reduced the pressor response to adrenaline but not to noradrenaline. PMID- 4313802 TI - Relative potencies of some false transmitters on isolated human smooth muscle. PMID- 4313803 TI - The effects of morphine-like substances and their antagonists on transmission at the neuro-effector junction of the myenteric plexus-longitudinal muscle preparation of the guinea-pig ileum. PMID- 4313805 TI - [Studies of Porter-Silber chromogen content in the plasma of schizophrenic and diabetic patients in various loading conditions]. PMID- 4313804 TI - Insulin release by isolated pancreatic islets of the mouse incubated in vitro. PMID- 4313806 TI - [Effect of corticotropin (ACTH) and cortisone on the activity of some glycosidases in the rat intestinal mucosa]. PMID- 4313807 TI - The functioning and functional reserve of the adrenal cortex in relation to age. PMID- 4313808 TI - [Histochemistry of complex lipids. I. Demonstration of vic-glycol groups]. PMID- 4313809 TI - [Histochemistry of complex lipids. II. Reactivity of peroxides]. PMID- 4313810 TI - The enzyme histochemistry of developing brown fat in the fetal rat. PMID- 4313811 TI - Malformative syndrome with cryptophthalmia. PMID- 4313812 TI - Experimental copper deficiency in sheep. PMID- 4313813 TI - [Medical therapy of trophoblastic tumors]. PMID- 4313814 TI - [Preliminary observations on a extensive list of tumors of the theca-granulosa cell complex]. PMID- 4313816 TI - Effects of phlorizin on membrane cation-dependent adenosine triphosphatase and p nitrophenyl phosphatase activities. PMID- 4313815 TI - Inosinic acid dehydrogenase in mammalian tissues. PMID- 4313818 TI - [Renin and angiotensin]. PMID- 4313817 TI - Enhancement of brain glutamate dehydrogenase activity and glutamate oxidation by adenine nucleotides. PMID- 4313819 TI - [Tissue collagenolytic enzymes]. PMID- 4313820 TI - [Peripheral nerve diseases. Physiopathology and classification]. PMID- 4313821 TI - [Critical study of the reinforcement of the adrenal glands at the end of several moths of corticotherapy]. PMID- 4313822 TI - [Some objectives of analysis and algorithms for processing (on electronic computers) summated electric signals in nerves]. PMID- 4313823 TI - [Primary multiple Paget's carcinoma]. PMID- 4313824 TI - [Glomus tumor of the stomach]. PMID- 4313825 TI - [Observation of glomus tumors of the middle ear and jugular vein]. PMID- 4313826 TI - [Stimulators and inhibitors of insulin secretion. Physiological and pharmacological interferences. Synergisms and antagonisms]. PMID- 4313827 TI - [Morphology and histochemistry of insulin secretion]. PMID- 4313828 TI - [A transplantable insuloma of the Syrian hamster Mesocricetus auratus auratus. Review of its properties and of its effects on the host]. PMID- 4313829 TI - Biochemical reactions in essentially nonaqueous systems. PMID- 4313830 TI - Factors which preclude growth of bacteria at low temperature. PMID- 4313831 TI - Studies on the mechanism of freezing damage to mouse liver using a mitochondrial enzyme assay. II. Comparison of slow and rapid cooling rates. PMID- 4313832 TI - Isolation of golgi apparatus from rat liver. 3. Lipid and protein composition. PMID- 4313833 TI - Fine structure of chromatolytic feline motoneurons. PMID- 4313834 TI - Some recent results in the chemistry and stereochemistry of vitamin D and its isomers. PMID- 4313835 TI - [Behavior of the enzymatic systems in renal cells in cercopithecus and rhesus due to the effect of SV 40 virus]. PMID- 4313836 TI - [Elution by guanidine thiocyanate of newly synthesized mammalian cell DNA from methylated albumin kieselguhr columns]. PMID- 4313838 TI - Glyceraldehydephosphate dehydrogenase from liver. I. Isolation and characterization of the bovine liver enzyme. PMID- 4313837 TI - [Changes in the phospholipid content of liver microsomes following various pretreatments of rats and guinea pigs]. PMID- 4313839 TI - Control of multiplication of uninfected rat cells and rat cells converted by murine sarcoma virus. PMID- 4313840 TI - Nuclear alterations in mammalian cells induced by L-canavanine. PMID- 4313842 TI - Polyamide-kieselguhr layer chromatography of antipyretics. PMID- 4313841 TI - A melanin-dispersing effect of cyclic adenosine monophosphate on Fundulus melanophores. PMID- 4313843 TI - Glucose utilization and hepatic enzyme activities in young gnotobiotic ruminants. PMID- 4313845 TI - Virulence of respiratory viruses. PMID- 4313844 TI - Relationship of bacteria to the etiology of periodontal disease. PMID- 4313846 TI - The immunodepressive effect of a murine plasmodium and its interaction with murine oncogenic viruses. PMID- 4313847 TI - Isolectric focusing of Clostridium perfringens alpha- and theta- toxins. PMID- 4313848 TI - Chemodectoma. PMID- 4313849 TI - Initiation of polyribosome formation in poliovirus-infected HeLa cells. PMID- 4313850 TI - Induction of virus multiplication in 3T3 cells transformed by a thermosensitive mutant of polyoma virus. I. Isolation and characterization of Ts-a-3T3 cells. PMID- 4313851 TI - Induction of virus multiplication in 3T3 cells transformed by a thermosensitive mutant of polyoma virus. II. Formation of oligometric polyoma DNA molecules. PMID- 4313852 TI - Interaction of closed circular DNA with intercalative dyes. II. The free energy of superhelix formation in SV40 DNA. PMID- 4313853 TI - Steroid myopathy complicating McArdle's disease. PMID- 4313854 TI - The role of skin areas adjacent to extensor muscles in motor neurone excitability: evidence bearing on the physiology of Babinski's response. PMID- 4313855 TI - Remarkable recovery of a steroid-responsive recurrent polyneuropathy. PMID- 4313856 TI - Changes in the forearm associated with median nerve compression at the wrist in the guinea-pig. PMID- 4313857 TI - [Response of the ovarian tumors induced in intrasplenic ovarian graft to administered gonadotrophic hormones]. PMID- 4313858 TI - Experimental canine herpesvirus in the gnotobiotic dog. PMID- 4313859 TI - Comparative effects of temperature exposure on mass and oxidative enzyme activity of brown fat in insectivores, tupaiads and primates. PMID- 4313861 TI - Phytochemical investigation of Egyptian Senecio. II. Alkaloids of Senecio aegyptius, S. desfontainei, S. vulgaris, S. petasitis and S. mikanioides. PMID- 4313860 TI - Free fatty acids in cultured cells. PMID- 4313863 TI - Sural nerve biopsy. PMID- 4313862 TI - Cytomegalovirus as a cause of mental retardation. PMID- 4313864 TI - [Treatment of hypotension in anesthesiological practice. Indications and limitations of modern hypotensive drugs]. PMID- 4313865 TI - Cyclic adenosine 3',5'-monophosphate formation in brain slices: stimulation by batrachotoxin, ouabain, veratridine, and potassium ions. PMID- 4313866 TI - Ouabain-dependent incorporation of 32P from p-nitrophenyl phosphate into a microsomal phosphatase. PMID- 4313867 TI - [Advances in the diagnosis and evaluation of functional disorders of peripheral nerves]. PMID- 4313868 TI - Observations on the primary structure of the 23S ribosomal RNA from E. coli. PMID- 4313869 TI - Some properties of angiotensin converting enzyme in the lung in vivo. PMID- 4313870 TI - Simultaneous measurement of cytochrome a3 reduction and chemoreceptor afferent activity in the carotid body. PMID- 4313871 TI - The effect of vitamin D on absorption of calcium and the template activity of chromatin in intestines of rats and chicks. PMID- 4313872 TI - [Poliomyelitis in Poland in the years 1966-1967]. PMID- 4313873 TI - [Epidemic of respiratory tract infection in young children caused by type 3 adenovirus]. PMID- 4313875 TI - [Human cytomegalic infection]. PMID- 4313874 TI - Correlation between the radioprotective effect of some substances with neurotropic action and inhibition of the respiratory enzymes. PMID- 4313876 TI - [Relations between the skin and endocrine glands]. PMID- 4313877 TI - [Influence of the lipid extract "B" isolated from the thymus gland on the development of Crocker 180 sarcoma in mice]. PMID- 4313878 TI - [Histological changes of the anterior pituitary and the adrenal gland after the administration of corticotropin and cortisone in male white rats]. PMID- 4313879 TI - [Thecoblastoma; clinical case]. PMID- 4313880 TI - Ultra-structural changes in vestibular sensory end organs after viomycin sulfate intoxication. PMID- 4313881 TI - [Clinical aspects of primary cancer of the liver. Study based on 92 cases]. PMID- 4313882 TI - [Gardner's syndrome with acromegaly and mixed tumor of the parotid. A case]. PMID- 4313883 TI - Studies of lysosomal alpha-glucosidase. I. Purification and properties of the rat liver enzyme. PMID- 4313884 TI - Metabolism and subcellular location of 25-hydroxycholecalciferol in intestinal mucosa. PMID- 4313885 TI - Substituent effects on pyridinium ring-opening reactions. Facile ring opening of 1-(N,N-dimethylcarbamoyl)nicotinamide cation. PMID- 4313886 TI - An electron paramagnetic resonance study of short-lived free radicals from nucleic acid constituents and related compounds in aqueous solution. PMID- 4313887 TI - Effect of D (minus)- and L (plus)-threo-chloramphenicol on nucleotide and related respiratory activities in yeast undergoing metabolic repression and de repression. PMID- 4313888 TI - [Fractionation and characteristics of brain phosphoinositides]. PMID- 4313889 TI - Content, synthesis and collectability of amino acids in various structures of the brains of rhesus monkeys. PMID- 4313890 TI - Inhibitory binocular interaction in the lateral geniculate body of the cat. PMID- 4313892 TI - The cortical projection onto the paramedian reticular and perihypoglossal nuclei (nucleus praepositus hypoglossi, nucleus intercalatus and nucleus of Roller) of the medulla oblongata of the cat. An experimeal-anatomical study. PMID- 4313891 TI - Monosynaptic excitation and inhibition of thoracic motoneurons by fibers in the medial longitudinal fasciculus. PMID- 4313894 TI - Community care--a study of the psychiatric morbidity of a Salvation Army hostel. PMID- 4313893 TI - The fine structure of the later vestibular nucleus in the rat. II. Synaptic organization. PMID- 4313895 TI - [Melanotic progonoma in childhood located in the maxilla]. PMID- 4313896 TI - Cobaloximes(II) and vitamin B12r as oxygen carriers. Evidence for monomeric and dimeric peroxides and superoxides. PMID- 4313898 TI - Analogs of angiotensin II. II. Mechanism of receptor interaction. PMID- 4313897 TI - Analogs of angiotensin II. I. Solid phase synthesis. PMID- 4313899 TI - Influence of endogenous and exogenous cyclic 3',5'-AMP on contractile responses induced by oxytocin and calcium in isolated rat uterus. PMID- 4313900 TI - Effect of glucose on lipolysis and energy metabolism in fat cells. PMID- 4313901 TI - Retroperitoneal seminomas without evidence of primary growth. PMID- 4313902 TI - [Abortion caused by type II Herpesvirus. Isolation of the virus from cultures of zygotic tissues]. PMID- 4313903 TI - [Korsakoff's post-encephalic syndrome]. PMID- 4313904 TI - [Orthostatic hypotension and peripheral neuropathy in the course of bronchial carcinoma]. PMID- 4313905 TI - [Variations in the renin-angiotensin-aldosterone system and in the antidiuretic hormone induced within 5 days by a contraceptive drug. Rapid action of a contraceptive drug on the hormones controlling water and salt metabolism]. PMID- 4313906 TI - Indoleamines and the central nervous system; a sounding of their clinical significance. PMID- 4313907 TI - Steroid hormones: effects on adenyl cyclase activity and adenosine 3',5' momophosphate in target tissues. AB - The adenyl cyclases of chick oviduct and rat prostate were not stimulated by estrogen and testosterone, respectively, suggesting that growth and differentiation of these target tissues are not mediated by adenosine 3',5' monophosphate. Estrogen acutely activated adenyl cyclase in the castrate rat uterus, but this was prevented by administration of DL-propranolol, suggesting that the effect was mediated by catecholamines. Progesterone produced a delayed stimulation of oviduct adenyl cyclase preceding and concomitant with the induction of synthesis of avidin. PMID- 4313909 TI - Encapsidation of free host DNA by simian virus 40: a simian virus 40 pseudovirus. AB - Under specified growth conditions, simian virus 40 encapsidated host DNA in a noncircular form free of viral DNA. Two bands of virus particles were present in cesium chloride equilibrium density centrifugation. The host DNA species contained in the upper band was of a lower molecular weight than the DNA present in the mature virus in the lower band. PMID- 4313908 TI - Cyclic adenosine monophosphate: andromimetic action on seminal vesicular enzymes. AB - Administration of adenosine 3',5'-monophosphate with theophylline produced testosterone-like induction of hexokinase, phosphofructokinase, pyruvate kinase, and glucose-6-phosphate dehydrogenase in the seminal vesicles of both orchidectomized and immature rats. The N(6)-O(2)'-dibutyryl analog of this cyclic nucleotide produced greater increases in vesicular enzyme activities than those induced by the parent compound. The observed enhancement of the key glycolytic enzymes and of hexose monophosphate shunt dehydrogenase was significantly inhibited by actinomycin D and cycloheximide. The evidence indicates that cyclic adenosine monophosphate may be involved as an intermediary in the action of androgenic hormones on male accessory sex organs. PMID- 4313910 TI - [Thromboembolic complications during treatment by estro-progestational drugs. Critical study of 3 cases]. PMID- 4313911 TI - [On a simple method of research in renal physiology, the collection of urine minute by minute]. PMID- 4313912 TI - [Severe thrombopenia due to rubella in adults]. PMID- 4313913 TI - [Must one reveal to the patient his proximate death?]. PMID- 4313914 TI - [Treatment of osseus suppuration by hyperbaric oxygenation]. PMID- 4313915 TI - [Therapeutic results of hyperbaric oxygen in varicose ulcer]. PMID- 4313916 TI - [Familial leukemia]. PMID- 4313918 TI - Studies on the relationship of viruses to the origin of human breast cancer. II. Viruslike particles in human breast tumors. PMID- 4313917 TI - The physiologic regulation of erythrocyte metabolism. PMID- 4313919 TI - Evolution of the juxtaglomerular apparatus in the vertebrate kidneys. PMID- 4313920 TI - On the pressor effect of angiotensin and renin before and after nephrectomy in dogs. PMID- 4313921 TI - [A case of tympano-jugular paraganglioma]. PMID- 4313922 TI - The influence of hormones on melanogenesis. PMID- 4313924 TI - Rat hepatoma DNA polymerase: partial analysis of the in vitro DNA product. PMID- 4313923 TI - A specific binding site for 3',5' cyclic AMP in rat parotid microsomes. PMID- 4313925 TI - Resolution of the methionine synthetase system from Escherichia coli K-12. PMID- 4313926 TI - Solubilization of myocardial adenyl cyclase. PMID- 4313927 TI - Characterization of respiration-deficient mutant of Saccharomyces cerevisiae lacking cytochromes a and c. PMID- 4313928 TI - Four quinone reduction sites in the NADH dehydrogenase complex. PMID- 4313929 TI - Ultraviolet spectral differences between phosphorylase a and b. PMID- 4313930 TI - Suppression of a pleiotropic mutant affecting glycerol dissimilation. PMID- 4313931 TI - A re-examination of the molecular weight of poliovirus RNA. PMID- 4313932 TI - 4-Thiouridine-specific spin-labeling of E. coli transfer RNA. PMID- 4313933 TI - Steroid biosynthesis by cultures of normal human adrenal tissue. PMID- 4313934 TI - Ion-induced water-proton chemical shifts and the conformational stability of macromolecules. PMID- 4313935 TI - Inhibition of mitochondrial respiration by hydroxylamine and its relation to energy conservation. PMID- 4313936 TI - Reduction of fatty acids to alcohols by cell-free preparations of Euglena gracilis. PMID- 4313937 TI - Periplasmic nucleoside diphosphate sugar hydrolase from Bacillus subtilis. PMID- 4313938 TI - Substrate-inhibited lactate dehydrogenase. Reaction mechanism and essential role of dissociated subunits. PMID- 4313939 TI - The influence of alloxan-diabetes and fasting on glycolytic and gluconeogenic enzyme activities of rat intestinal mucosa and liver. PMID- 4313940 TI - Dissociation of lipolysis and protein anabolism by ACTH, bovine growth hormone, and thyroid stimulating hormone in adipose tissue with dibutyryl cyclic AMP and theophylline. PMID- 4313941 TI - The effect of Ca2+ on the adenyl cyclase of calf brain. PMID- 4313942 TI - Mechanism of phosphorylation of phosphoprotein during oogenesis in trout in vivo. PMID- 4313943 TI - Uptake and metabolism of nicotinic acid by human blood platelets. Effects of structure analogs and metabolic inhibitors. PMID- 4313944 TI - [The angiotensin test in the differential diagnosis of hypertension]. PMID- 4313945 TI - [Unitary responses in hypothalamus anterior and median areas associated with variations in arterial pressure and volemia]. PMID- 4313946 TI - [Differential action of sodium gammahydroxybutyrate on dorsal radicular potentials provoked by segmental or cortical stimulation]. PMID- 4313947 TI - [Skeletal changes due to the endogenic and exogenic effect of corticosteroids (radiographic observations)]. PMID- 4313948 TI - [A study of the virucidal efficacy of ultraviolet rays in experimental disinfection of air and surfaces]. PMID- 4313950 TI - Entrapment of the posterior tibial nerve. A case report. PMID- 4313949 TI - Tarsal tunnel syndrome. A case report. PMID- 4313951 TI - [Deep cervico-facial cancer with skin ulcer]. PMID- 4313953 TI - [Bronchial adenoma]. PMID- 4313952 TI - Chronic oral ulceration. PMID- 4313954 TI - A survey of genetic resistance to leukosis-sarcoma viruses in commercial stocks of chickens. PMID- 4313956 TI - Transient myasthenia of the newborn. Clinical and electromyographic studies. PMID- 4313955 TI - [The role of adrenocorticotropic hormone and corticosteroids in the genesis of Itsenko-Cushing disease]. PMID- 4313957 TI - Cooperative study in the evaluation of therapy in multiple sclerosis: ACTH vs placebo in acute exacerbation. PMID- 4313958 TI - Biochemical characteristics of experimental cerebral infarction: Evidence against lysosomal participation in early cell injury. PMID- 4313959 TI - Sensory levels associated with painful lesions affecting the spinal roots in man. PMID- 4313960 TI - Further studies on the pathogenic mechanisms of multiple sclerosis with a proposal for a therapeutic approach. PMID- 4313961 TI - Hypoventilation syndrome and obesity: A polygraphic study. PMID- 4313962 TI - The excitation pattern of fusimotor and alpha-motor fibers after cerebellar ablation. PMID- 4313964 TI - Studies of the ocular countertoriion reflex. PMID- 4313963 TI - Electrically stimulated release of norepinephrine-H3 and serotonin-H3 from mammalian brain slices: a model for studying the effects of drugs on putative central neurotransmitters. PMID- 4313965 TI - Behavioral correlates of blood flow and myoglobin concentration in skeletal muscle in cat. PMID- 4313966 TI - The peripheral neuropathy of globoid cell leukodystrophy. PMID- 4313967 TI - L-dopa reversal of muscular spasm, vomiting and insomnia in a patient with an atypical form of familial dystonia. PMID- 4313968 TI - [Glucocorticoid function of the adrenal cortex in patients with thyrotoxicosis]. PMID- 4313969 TI - [Autopsy data on the incidence of cytomegaly in the Cherkass region]. PMID- 4313970 TI - [Amino acid content of cancerous tumors of the stomach in relation to characteristics of their histological structure]. PMID- 4313971 TI - Adenovirus type 8 keratoconjunctivitis in the United States. 3. Epidemiologic, clinical, and microbiologic features. PMID- 4313972 TI - Silica gel cataract extraction. PMID- 4313973 TI - Determination of lead chelated with ethylenediaminetetra-acetic acid in blood after precipitation of protein with perchloric acid. PMID- 4313974 TI - Retrograde jugular venography. PMID- 4313975 TI - Demonstration of virus particles in human genital warts. PMID- 4313976 TI - Infection of dogs and cats with a canine parainfluenza virus and the application of a conglutinating-complement-absorption test on cat serums. PMID- 4313977 TI - Syndactylism in a neonatal lamb. PMID- 4313978 TI - Relationship of infectious bovine keratoconjunctivitis virus to the virus of infectious bovine rhinotracheitis. PMID- 4313979 TI - Conditions in vitro which affect respiratory control and capacity for respiration linked phosphorylation in brown adipose tissue mitochondria. PMID- 4313980 TI - The nucleotide sequence of methionine transfer RNA-M. PMID- 4313982 TI - Desensitization of yeast phosphofructokinase to ATP-inhibition by a protein fraction from yeast. PMID- 4313981 TI - The properties of mitochondria enriched in vitro with cholesterol. PMID- 4313983 TI - Flavin radical chelates as studies by electron spin resonance and isotopic substitution. PMID- 4313984 TI - Relation of dopa and 5-HTP to convulsions induced by strychnine and leptazol. PMID- 4313985 TI - Two cases of Paget's disease of the nipple. PMID- 4313986 TI - Luteal and endometrial phosphatase activities during the porcine estrous cycle. PMID- 4313987 TI - Hypophosphatasia: case reports. PMID- 4313988 TI - A study of viral etiology of aseptic meningitis and encephalitis in Cairo. PMID- 4313990 TI - Quantitative methods for the concentration of visuses in wastewater. PMID- 4313989 TI - Adenoma of the nipple. PMID- 4313991 TI - New antigens in hamster embryo cells transformed in vitro by bovine papilloma extracts. PMID- 4313992 TI - Effect of hypothalamic stimulation on blood glucose in the rabbit. PMID- 4313994 TI - ESR triplet spectra of acridine dyes. PMID- 4313993 TI - Effects of alpha methyl tyrosine and p-chlorophenylalanine on the regulation of ACTH secretion. PMID- 4313995 TI - ESR spectra of some irradiated donor-acceptor systems. PMID- 4313997 TI - Selective in vitro antiviral effect on myxovirus strains of guanidine derivatives. PMID- 4313996 TI - The development of ideas about the mode of action of insulin. PMID- 4313998 TI - Some properties of alkaline phosphatase in Bacillus species. PMID- 4313999 TI - Heart glycosides in poliovirus host cell interaction. I. Effect of digoxin and digitoxin and their aglucons on one step growth curves. PMID- 4314000 TI - Heart glycosides in poliovirus host cell interaction. II. Effect of the time of addition on stimulatory or inhibitory action. PMID- 4314001 TI - Excitation of photoreceptors. A review. PMID- 4314002 TI - Quantitative determinations by ion-pair extraction. 5. Determination of anions by extraction as ion pairs with a fluorescent cation. PMID- 4314003 TI - [Clinico-hemodynamic findings in obstructive hypertrophic myocardiopathy]. PMID- 4314004 TI - [Hemodynamic aspects of splanchnic circulation and its changes under the influence of sympathomimetic drugs]. PMID- 4314005 TI - Epidemiologic and field observations on avian influenza in Minnesota turkeys. PMID- 4314006 TI - Serology and gross lesions of turkeys inoculated with an avian influenza A virus, a paramyxovirus, and Mycoplasma gallisepticum. PMID- 4314007 TI - Avian influenza virus infections. I. Characteristics of influenza A-turkey Wisconsin-1966 virus. PMID- 4314008 TI - Preincubation treatment of chicken hatching eggs infected with Salmonella pullorum. PMID- 4314009 TI - [Attempts at vaccination against bovine hypodermyiasis with a vaccine containing crude collagenase extracted from Hypoderma lineatum 1st stage larva]. PMID- 4314010 TI - The mode of cerebello-thalamic relay transmission investigated with intracellular recording from cells of the ventrolateral nucleus of cat's thalamus. PMID- 4314012 TI - [Dependence of recurrent inhibition on conditions of antidromal and orthodromal stimulation]. PMID- 4314011 TI - Synaptic potentials recorded in brain slices and their modification by changes in the level of tissue ATP. PMID- 4314013 TI - [On the importance of mediator sources in the terminal parts of noradrenergic neurons for synaptic transmission of impulses to smooth muscle]. PMID- 4314014 TI - [Burkitt's tumor--a literature study with own case reports]. PMID- 4314015 TI - [Microelectronic and microcinematographic investigations on the anti-amebic action of aminosidine]. PMID- 4314016 TI - [Function of adrenal cortex in physiological jaundice in newborn infants]. PMID- 4314017 TI - [Degenerative myelo-radiculo-neuropathy. Review of the literature concerning Dejerine-Sottas disease, Charcot-Marie-Tooth disease and the Roussy-Levy syndrome. Presentation of 6 personal cases]. PMID- 4314018 TI - [Blood serotonin concentration in stomach cancer patients]. PMID- 4314019 TI - [The kinetics of the survival rate of patients following radical surgery for stomach cancer]. PMID- 4314020 TI - [The function of the genome of iivated Sendai virus in the formation of artificial heterokaryons]. PMID- 4314021 TI - [Formation of tumors from cells transformed in vitro by SV40 virus]. PMID- 4314022 TI - [Detection of virus-like formations in cells of transplanted adenocarcinoma 755]. PMID- 4314023 TI - The influence of collengase on the periodontal ligament of orthodontically rotated teeth. PMID- 4314024 TI - Urinary adenosine 3',5'-monophosphate excretion in affective disorders. PMID- 4314025 TI - Preliminary results of azathioprine treatment in severe rheumatic disease. PMID- 4314026 TI - Elasticity of human skin in vivo. A study of the physical properties of the skin in rheumatoid arthritis and the effect of corticosteroids. PMID- 4314027 TI - Lymphangiography. PMID- 4314028 TI - [Spasma-in-flexion syndrome, callosal agenesis, chorioretinal abnormalities]. PMID- 4314029 TI - [Irregular radiologic aspects of metaphyses of the fingers in children with hypothalamo-hypophyseal insufficiency]. PMID- 4314030 TI - Quantitative radiation effects in hemoproteins and their constituents. AB - In order to verify the "radiation protection" effect of prosthetic groups in irradiated conjugated proteins and the influence of their electronic structure on intramolecular excitation transfer, two series of substances were examined. The first was composed of ferrihemoglobin and its constituents and the second was composed of similar hemoproteins with heme groups with major differences in electronic structure. The results point to a strong radiation protection effect of the heme groups and a dependence of radical yield of hemoproteins on the electronic structure of the heme. A possible interpretation of this latter effect is discussed. PMID- 4314032 TI - Primary clostridial pneumonia and empyrema. PMID- 4314031 TI - Evaluation of the calcifying characteristics of biological fluids and inhibitors of calcification. PMID- 4314033 TI - Sural nerve biopsies in pediatric neurological disorders. PMID- 4314034 TI - Ultrastructural-characteristics of surface IgM reactive malignant lymphoid cells. PMID- 4314035 TI - Small angle light scattering of bioparticles. 2. Cells and cellular organelles. PMID- 4314036 TI - Mixed tumour of sub-maxillary gland in a young boy. Report of a case. PMID- 4314037 TI - Processing of 45 s nucleolar RNA. PMID- 4314038 TI - Nerve growth factor in human sera. PMID- 4314039 TI - The administration of the nerve growth factor to children with widespread neuroblastoma. PMID- 4314040 TI - Congenital atypical benign chondroblastoma of a rib. PMID- 4314041 TI - [Use of iodated triglycerides (lipidol) as lipid absorption test in premature infants]. PMID- 4314042 TI - [Sleep research and its clinical aspects]. PMID- 4314043 TI - Pure gonadal dysgenesis with progressive hirsutism. PMID- 4314044 TI - Physiologic and pharmacologic regulation of bone resorption. PMID- 4314045 TI - Postoperative neurological complications of antibiotic therapy. PMID- 4314046 TI - Virus pneumonia in calves. PMID- 4314047 TI - Duality of conduction mechanism in bipolar cells of the frog retina. PMID- 4314048 TI - Effect of diethylpyrocarbonate on the conformation and enzymic activity of d glyceraldehyde-3-phosphate dehydrogenase. PMID- 4314049 TI - Information content of end-plate potentials (short communication). PMID- 4314050 TI - Catecholamines and metabolism of human adipose tissue. I. Comparison between in vitro effects of noradrenaline, adrenaline and theophylline on lipolysis in omental adipose tissue. PMID- 4314051 TI - [Comparative effectiveness of gentamycin and other antibiotics in experiment]. PMID- 4314052 TI - [Incidence of the episomal factor of multiple drug resistance (R-factor) among clinical strains of the causative agent of dysentery]. PMID- 4314053 TI - Reaction mechanism of 20 beta-hydroxysteroid dehydrogenase determined by equilibrium rate exchange. PMID- 4314054 TI - Studies on the respiratory chain-linked reduced nicotinamide adenine dinucleotide dehydrogenase. XVI. Characteristics of the membrane-bound dehydrogenase in Candida utilis and Saccharomyces cerevisiae. PMID- 4314055 TI - Different molecular forms of potato apyrase. PMID- 4314056 TI - Inhibition of respiration in submitochondrial particles by uncouplers of oxidative phosphorylation. PMID- 4314057 TI - Comparative kinetic behavior of the photoinduced EPR signal observed in whole cells and cell free preparations of Rhodospirillum rubrum. PMID- 4314059 TI - Long-term use of depot tetracosactrin. PMID- 4314058 TI - Correlation between angiographic diagnosis and histology of pancre atic insulomas. PMID- 4314060 TI - Rate of disappearance of endogenous insulin from the circulation after removal of insulinomas. AB - In two patients with insulinomas a rapid rate of disappearance of insulin from the circulation was found after the tumours had been removed. In a third case the rate of disappearance was slower but the insulin was not immunologically identical to normal human insulin standards, as it was in the other two cases. PMID- 4314061 TI - [Phosphomonoesterases and embryonic developments]. PMID- 4314062 TI - [Hypophosphatasia with significant changes in teeth and bones in a 4-year-old boy]. PMID- 4314063 TI - Simultaneous determination of cortisol and corticosterone in urine. PMID- 4314064 TI - The natural history of primary and secondary malignant tumours of the liver. 3. The prognosis for patients with hepatic metastases from pancreatic carcinoma verified by laparotomy. PMID- 4314066 TI - Some studies on the effect of androgens on adrenal cortical function of rats. PMID- 4314065 TI - Response of chick oviduct adenyl cyclase to steroid hormones. PMID- 4314067 TI - Stimulation of corticotropin release by corticotropin-releasing factor (CRF) or by vasopressin following intrapituitary infusions in unanesthetized dogs: inhibition of the responses by dexamethasone. PMID- 4314068 TI - Prevention of Mammary gland defects in experimental congenital adrenal hyperplasia due to inhibition to 3 beta-hydroxysteroid dehydrogenase in rats. PMID- 4314069 TI - Circadian rhythm and stress-induced changes in hypothalamic content of corticotropin-releasing activity during postnatal development in the rat. PMID- 4314070 TI - Evaluation of angiotension II metabolism in sheep by radioimmunoassay. PMID- 4314071 TI - Role of catecholamines in stimulating the release of pituitary ovulating hormone(s) in rats. PMID- 4314073 TI - A sporadic case of juvenile amyotrophic lateral sclerosis; semi-quantitative and histo-enzymatical study of the denervated muscles. PMID- 4314072 TI - The effect of tetanus toxin on neuromuscular transmission. PMID- 4314074 TI - [After care of jaw fractures with portable mouth irrigation equipment]. PMID- 4314075 TI - Studies on the development of the gonads in embryos of the domestic pig (Sus scrofa dom. L.). IV. Cells containing PAS-positive grains in the differentiating testis anlage. PMID- 4314076 TI - Histochemical studies on the action of aflatoxins. I. A cytological and cytochemical study of the liver of rats fed a diet contaminated with Aspergillus flavus. PMID- 4314077 TI - Cortisol is secreted episodically by normal man. PMID- 4314078 TI - Effect of cold exposure on serum thyrotropin. PMID- 4314079 TI - Nasopharyngeal angiofibroma of the maxilla: report of case. PMID- 4314080 TI - [Large hematoma within a histiocytoma raising diagnostic problems with melanoma]. PMID- 4314081 TI - Four base-specific nucleoside 5'-triphosphatases in the subviral core of reovirus. PMID- 4314083 TI - Strychnine, glycine and vertebrate postsynaptic inhibition. PMID- 4314082 TI - Hydrolysis of phospholipid esters localized in lysosomes and related structures of rat muscle cells in culture. PMID- 4314084 TI - [Digestive manifestations in respiratory diseases caused by viruses in infants and children]. PMID- 4314085 TI - [Medullary-pheochromocytoma and papillary chemodectoma carcinoma syndromes. Comparative study]. PMID- 4314086 TI - [Reminder of the neuropsychological symptoms of right hemispheric lesions]. PMID- 4314087 TI - Multiple sclerosis: pilot therapeutic trial of immunosuppressants. PMID- 4314088 TI - [2-dimensional chromatography of a corticosteroid mixture on thin layer of KSK silica-gel]. PMID- 4314089 TI - [The molecular heterogeneity of cholinesterases]. PMID- 4314090 TI - [Cyclic adenosine-3',5'-monophosphate and its biological role]. PMID- 4314091 TI - [Activities pentosephosphate cycle hexokinases and dehydrogenases in transplanted mouse hepatomas]. PMID- 4314092 TI - [Splitting of thiamine phosphates in heart muscle in adrenaline-induced myocarditis and in normal animals]. PMID- 4314094 TI - Studies of pituitary-adrenocortical function in ulcerative colitis. PMID- 4314093 TI - [Cordiamin effect on NAD-glucohydrolase in rabbit myocardium]. PMID- 4314095 TI - Adenine compounds on changes in optical density and motility of frog gastric mucosa. PMID- 4314096 TI - Importance of aerobic and anaerobic metabolism in renal concentration and dilution. PMID- 4314097 TI - A phylogenetic study of the renin-angiotensin system. PMID- 4314098 TI - [Cylindroma of the cervix uteri]. PMID- 4314099 TI - Blood groups and their relation to serum phosphohydrolases. PMID- 4314100 TI - Physiology of prostatic phosphohydrolase secretion. PMID- 4314102 TI - Soluble and membrane-associated forms of acid phosphatase associated with the lysosomal fraction of rat liver. PMID- 4314101 TI - 5'-nucleotidase of plasma membranes of the rat liver: studies on subcellular distribution. PMID- 4314103 TI - Some properties and possible physiological functions of phosphotransferase activities of microsomal glucose-6-phosphatase. PMID- 4314105 TI - Clinical application of phosphohydrolase measurements in cancer. PMID- 4314104 TI - Oligo- and polysaccharide inhibition of muscle transferase D phosphatase. PMID- 4314106 TI - Oxidative phosphorylation in fractionated bacterial systems. XLII. The effect of coupling factors on urea-treated particles from M. phlei. PMID- 4314107 TI - Oxidative phosphorylation in fractionated bacterial systems. 43. Coupling factors associated with the NAD+ linked electron transport pathway. PMID- 4314108 TI - The activation and inactivation of the acyl phosphatase activity of glyceraldehyde-3-phosphate dehydrogenase. PMID- 4314110 TI - Studies on myosin catalysis and modification. PMID- 4314109 TI - Analytical differential centrifugation: an analysis of the sedimentation properties of synaptosomes, mitochondria and lysosomes from rat brain homogenates. PMID- 4314111 TI - Structural relations in aldolases purified from rat liver and muscle and Novikoff hepatoma. PMID- 4314112 TI - The identity of the aldolases isolated from rat muscle and primary hepatoma. PMID- 4314113 TI - Fructose diphosphatase from rabbit muscle. 3. Isolation of enzyme-substrate and enzyme-adenosine monophosphate complexes. PMID- 4314114 TI - On the occurrence of respiratory components in calf thymus nuclei. II. Cytochrome oxidase activity. PMID- 4314115 TI - Purine metabolism in germinating wheat embryos. AB - 1. Both the acid-soluble fraction and the nucleic acid fraction of wheat embryos were extensively labelled after incubation for 6hr. in the presence of [8 (14)C]adenine. Subsequent incubation in the absence of labelled adenine resulted in no loss of radioactivity to the medium during a 48hr. period. Radioautography indicated that during this period there was a continuous increase in the radioactivity present in the acid-insoluble fractions of the root and leaf tissues relative to that present in the coleorhiza and coleoptile. 2. During incubation at 25 degrees there was a 26-fold increase in the activity of 3' nucleotidase between 4hr. and 24hr.; the activities of enzymes hydrolysing AMP and IMP increased to a smaller extent. The activities of adenine phosphoribosyltransferase and hypoxanthine phosphoribosyltransferase increased three- to five-fold during incubation at 25 degrees for 24hr. 3. Adenosine kinase, inosine phosphorylase and 5-phosphoribosyl pyrophosphate synthetase activities were high in extracts from dry embryos and did not increase during 48hr. at 25 degrees . 4. The increase in 3'-nucleotidase activity was prevented by cycloheximide, cryptopleurine or incubation at 4 degrees , but not by actinomycin D; these treatments did not depress the activity of the other enzymes measured. 5. The results are discussed in relation to RNA translocation within the wheat embryo during germination. PMID- 4314117 TI - Periodate oxidation studies of human pituitary follicle-stimulating hormone. AB - A preparation of human pituitary follicle-stimulating hormone was subjected to periodate oxidation, borohydride reduction and acid hydrolysis. Comparison of the analysis of the remaining intact carbohydrate and amino acid units with the analyses of the original material and identification of the carbohydrate fragments permit some structural assignments to the molecule of follicle stimulating hormone. The results of radioimmunological assay of fragments of the molecule of follicle-stimulating hormone suggest that, although the carbohydrate component is essential for biological activity, it is not a requirement for immunological activity, which appears to be a function of the protein moiety. PMID- 4314116 TI - The effect of starvation on the incorporation of palmitate into glycerides and phospholipids of rat liver homogenates. AB - 1. Glyceride biosynthesis from glycerol phosphate and [1-(14)C]palmitate was studied in liver homogenates of rats that were fed ad libitum or starved for 36 40hr. The changes in enzyme activity were related to total DNA content or total liver homogenate as these were found to be equivalent and to be the most meaningful parameters. 2. In liver homogenates from fed rats, labelled palmitate was incorporated mainly into phosphatidate (58% of the total incorporation into lipids), diglycerides (25%) and triglycerides (16%), whereas monoglycerides, cholesterol esters and phospholipids other than phosphatidate were labelled only to a small extent. Addition of particle-free supernatant to full homogenates increased the total incorporation of palmitate by 45% and the pattern of incorporation altered to 53% incorporated into triglycerides, 24% into diglycerides and 17% into phosphatidate. This result suggested that, in liver homogenates, phosphatidate phosphohydrolase (EC 3.1.3.4) may be rate-limiting in the biosynthesis of glycerides via the glycerol phosphate pathway. 3. Upon starvation, the amount of palmitate incorporated per liver into total phospholipids plus glycerides was decreased to between 68% and 75% of that observed with fed animals. In homogenates from fed animals 41-44% of the labelled phospholipids plus glycerides was in glycerides; this value increased to between 63% and 75% with starved rats. Of the palmitate incorporated into total phospholipids, between 85% and 86% was found in phosphatidate, independent of the nutritional state of the animal. The ratio of palmitate incorporated into triglycerides/diglycerides rose from 0.7, obtained with fed rats, to 1.0 with starved animals. 4. These results indicate that starvation caused a decrease in the activity (per total liver) of acyl-CoA-glycerol phosphate acyltransferase(s) (EC 2.3.1.15) and an increase in the activity of acyl-CoA-diglyceride acyltransferase (EC 2.3.1.20). The largest change, however, seemed to be related to the increased activity of the phosphatidate phosphohydrolase in the particle free supernatant. 5. The latter enzyme was assayed in the particle-free supernatant with membrane-bound phosphatidate as substrate. In starvation, the activity per total liver was increased to between 130% and 190% and the specific activity to between 180% and 320% of the values for fed rats. PMID- 4314118 TI - Isolation of chick intestinal nuclei. Effect of vitamin D3 on nuclear metabolism. AB - 1. Chick intestinal nuclei were isolated, with practically no contamination from other organelles and whole cells, by centrifugation through 2.4m-sucrose. 2. The proportions of RNA, DNA and protein of the isolated nuclei were unaffected by the vitamin D status of the birds. The RNA/DNA ratio was 0.15. 3. The incorporation of [5-(3)H]orotic acid into the rapidly labelled intestinal nuclear RNA, after a 10min. pulse of the orotic acid, was increased in vitamin D-deficient chicks only 10min. after a 125mug. dose of cholecalciferol. 4. There was no stimulation of the DNA-dependent RNA polymerase activity of the isolated nuclei from birds treated with cholecalciferol. 5. The results are discussed in relation to the changes occurring during the lag period, after administration of cholecalciferol and before Ca(2+) transport is detected, and the function of the vitamin. PMID- 4314119 TI - Metabolism of vitamin D. A new cholecalciferol metabolite, involving loss of hydrogen at C-1, in chick intestinal nuclei. AB - 1. A comparison was made of the nature and intestinal intracellular distribution of the metabolites formed in vitamin D-deficient chicks from [4 (14)C]cholecalciferol and [1-(3)H]cholecalciferol. 2. The simultaneous administration of the two radioactive substances showed the presence in blood, liver, intestine, kidney and bone of cholecalciferol, its ester, 25 hydroxycholecalciferol and a further metabolite of cholecalciferol more polar than 25-hydroxycholecalciferol. The (3)H/(14)C ratios in these four radioactive components were the same as that of the dosed material (4.7:1) with the exception of the most polar material. The (3)H/(14)C ratio was lower in the fourth, most polar, metabolite (0.4:1-1.8:1) in all tissues examined, with the exception of blood. 3. In the chick intestine the polar metabolite accounted for almost 70% of the radioactivity in this tissue after a dose of 0.5mug. of [4-(14)C,1 (3)H]cholecalciferol. This polar metabolite from the intestine also had the lowest (3)H/(14)C ratio of all the tissues. It appears that in the chick intestine the polar metabolite reaches a maximum concentration of 1ng./g. of tissue, above which it cannot be increased irrespective of the dose of the vitamin. 4. The intestinal intracellular organelle with the highest concentration of (14)C radioactivity is the nucleus, and this radioactivity is almost entirely due to the polar metabolite with the lowered (3)H/(14)C ratio, in this case <0.2:1. It appears to be further localized in the chromatin of the nuclei. However, about half of the polar metabolite in the intestine is extranuclear. 5. Double-labelled 25-hydroxycholecalciferol was prepared and after its administration to vitamin D-deficient chicks the polar metabolite with the lowered (3)H/(14)C ratio was detected in liver, kidney, intestine, bone, muscle and heart. 6. None of the polar metabolite with the lowered (3)H/(14)C ratio was detected 16hr. after dosing with either the double-labelled vitamin or the double labelled 25-hydroxycholecalciferol in blood and adipose tissue of vitamin D deficient chicks, nor in the intestine, liver and kidney of supplemented birds. 7. The reasons for this loss of (3)H relative to (14)C are discussed in relation to possible chemical structures of this new polar metabolite. PMID- 4314120 TI - A lipid intermediate in the synthesis of a poly-(N-acetylglucosamine 1-phosphate) from the wall of Staphylococcus lactis N.C.T.C. 2102. AB - 1. The enzymic synthesis of the wall polymer poly-(N-acetylglucosamine 1 phosphate) in Staphylococcus lactis N.C.T.C. 2102 was studied by using UDP [acetyl-(14)C]N-acetylglucosamine and the corresponding nucleotide containing (32)P. 2. Labelled material was extracted from the particulate enzyme preparation with butan-1-ol. Pulse-labelling experiments indicated that this material contained an intermediate in the biosynthesis. 3. The lipid intermediate was partially purified, and chemical and enzymic degradation showed that it was composed of N-acetylglucosamine 1-pyrophosphate in labile ester linkage to an organic-soluble alcohol, possibly a polyisoprenoid alcohol. The methanolysis of sugar 1-pyrophosphate derivatives, including nucleoside diphosphate sugars, is discussed in relation to degradation products obtained from the lipid. 4. The lipids from the particulate enzyme preparation probably contained another compound in which N-acetylglucosamine 1-phosphate is attached to an organic soluble alcohol; this may participate in the biosynthesis of another polysaccharide. 5. The function of the lipid intermediate in polymer biosynthesis is discussed. PMID- 4314122 TI - One-electron reactions of some mitochondrial components studied by pulse radiolysis. PMID- 4314121 TI - Pathways of glycogen synthesis in Novikoff ascites-hepatoma cells. AB - Affinity of glucose, fructose and mannose for tumour hexokinase and their rates of phosphorylation at saturation concentration have been correlated with rates of glycogen synthesis by intact tumour cells at different concentrations of the three substrates. Competition experiments with one sugar labelled and the other sugar unlabelled indicate inhibition of glycogen synthesis by the sugar with a low K(m) for hexokinase. Glycogen synthesis from glucose 1-phosphate in aged cells and from nucleoside in freshly prepared cells is stimulated by fructose and inhibited by glucose. The decrease in glycogen formation from glucose 1-phosphate by oligomycin is partially overcome by increased fructose concentrations. These results are explained by an activation of alpha-glucan phosphorylase by fructose and an inhibition of this enzyme by glucose. It is suggested that differences in localization of glucose 6-phosphate, available to the intact cell in various ways, determine its transformation into glycogen by either the UDP-glucose-alpha glucan glucosyltransferase reaction or by the alpha-glucan phosphorylase reaction. PMID- 4314123 TI - Intramitochondrial distribution of cytochrome P-450 in ox adrenal cortex. PMID- 4314124 TI - The long-wavelength absorption band of cytochrome c oxidase. PMID- 4314125 TI - Cytochrome c redox potentials as a function of the energy state in chromatophores. PMID- 4314126 TI - Phosphorylating respiratory membranes from Azotobacter vinelandii. PMID- 4314127 TI - The effects of calcium ions and adenosine diphosphats on the activity of nicotinamide-adenine dinucleotide-linked isocitrate dehydrogenase of muscle. PMID- 4314128 TI - Changes in subcellular distribution of enzymes during respiratory adaptation of Saccharomyces carlsbergensis. PMID- 4314129 TI - Studies on the phospholipids of yeast mitochondria. PMID- 4314131 TI - Isolation and partial characterization of apiogalacturonans from the cell wall of Lemna minor. AB - 1. A mild, reproducible extraction procedure, using 0.5% ammonium oxalate, was developed for the isolation of polysaccharides containing d-apiose from the cell wall of Lemna minor. On a dry-weight basis the polysaccharide fractions extracted with ammonium oxalate made up 14% of the material designated cell walls and contained 20% of the d-apiose originally present in the cell walls. The cell walls, as isolated, contained 83% of the d-apiose present in L. minor. 2. After extraction with ammonium oxalate, purified polysaccharides were obtained by DEAE Sephadex column chromatography and by fractional precipitation with sodium chloride. With these procedures the material extracted at 22 degrees C could be separated into at least five polysaccharides. On a dry-weight basis two of these polysaccharides made up more than 50% of the material extracted at 22 degrees C. There was a direct relationship between the d-apiose content of the polysaccharides and their solubility in sodium chloride solutions; those of highest d-apiose content were most soluble. 3. All the polysaccharides isolated appeared to be of one general type, namely galacturonans to which were attached side chains containing d-apiose. The d-apiose content of the apiogalacturonans varied from 7.9 to 38.1%. The content of esterified d-galacturonic acid residues in all apiogalacturonans was low, being in the range 1.0-3.5%. Hydrolysis of a representative apiogalacturonan with dilute acid resulted in the complete removal of the d-apiose with little or no degradation of the galacturonan portion. 4. Treatment of polysaccharide fractions with pectinase established that those of high d-apiose content and soluble in m-sodium chloride were not degraded, whereas those of low d-apiose content and insoluble in m-sodium chloride were extensively degraded. When the d-apiose was removed from a typical pectinase-resistant polysaccharide, the remainder of the polysaccharide was readily degraded by this enzyme. 5. Periodate oxidation of representative polysaccharide fractions and apiogalacturonans and determination of the formaldehyde released showed that about 50% of the d-apiose molecules were substituted at either the 3- or the 3' position. PMID- 4314130 TI - Characterization of rapidly labelled rat liver ribonucleic acid showing high affinity for columns of methylated albumin on kieselguhr. AB - Most of the rapidly labelled RNA from rat liver submitted to column chromatography on methylated albumin on kieselguhr remains tightly bound to the column and can only be recovered by elution with m-ammonia. The tightly bound RNA is composed mainly of DNA-like RNA. The binding capacity is dependent not only on base composition but also on molecular size: the heavier RNA molecules show a greater affinity to the column than do the lower-molecular-weight components. Rapidly labelled mouse liver and Saccharomyces cerevisiae RNA show similar behaviour to rat liver RNA on columns of methylated albumin on kieselguhr. PMID- 4314133 TI - [Electron model of synaptic transmission]. PMID- 4314132 TI - The stereospecificity of tritium distribution in [1-3H]- and [1,2-3H2] cholesterol and -cholecalciferol. PMID- 4314134 TI - [Demonstrations of new evolution stages of mouse mammary tumor virus: intracytoplasmic viral infraparticles and the formation of particle A]. PMID- 4314135 TI - [Properties of very active murine leukemogenic virus inhibitor]. PMID- 4314136 TI - The activity of the pituitary cells of the teleost Poecilia during the gestation cycle and the control of the gonadotropic cells. PMID- 4314137 TI - Histochemical studies of the neurosecretory system of Chirocephalus diaphanus Prevost (Crustacea: Anostraca). PMID- 4314138 TI - Microscopic examination of parathion activating microsomes from American cockroach fat body. PMID- 4314139 TI - Action of nicotine on neural synaptic transmission in the American cockroach. PMID- 4314140 TI - Release of a synaptically active material by nicotine in the central nervous system of the American cockroach. PMID- 4314141 TI - [A case of arterial hypertension imputable to an estroprogestational contraceptive. Implication of the renin-angiotensin-aldosterone system]. PMID- 4314142 TI - Differential responses to various ACTH-releasing stimuli in rats with hypothalamic implants of corticosteroids. PMID- 4314143 TI - Effects of isolation of medial basal hypothalamus on pituitary-adrenal and pituitary-ovarian functions. PMID- 4314144 TI - Metabolic and virologic studies in primate liver organ cultures. PMID- 4314145 TI - DNA synthesis in EB virus-containing Burkitt lymphoma cultures during a temperature cycling procedure. PMID- 4314146 TI - A new pressor factor in extract of rat aorta wall. PMID- 4314148 TI - The effect of parenteral and oral immunization on encephalomyocarditis infection in mice. PMID- 4314147 TI - Characterization of reptilian cell lines established at incubation temperatures of 23 to 36 degrees. PMID- 4314149 TI - Induction of interferon in lymphoblastoid cell lines. PMID- 4314150 TI - Herpesvirus hominis types I and II: a specific microindirect hemagglutination test. PMID- 4314151 TI - Differential decrease of "shuttle" enzymes of extramitochondrial NADH2 oxidation of heart muscle during progressive thiamine deficiency. PMID- 4314153 TI - Lactate dehydrogenase in the rat mammary gland. PMID- 4314152 TI - Non-antigen-antibody precipitin reactions observed with dextran sulfate, DEAE dextran, antibiotics, proteins, and phospholipids. PMID- 4314154 TI - EBV antibodies in family contacts of patients with infectious mononucleosis. PMID- 4314155 TI - Strontium inhibition of vitamin D3-induced calcium-binding protein (CaBP) and calcium absorption in chick intestine. PMID- 4314156 TI - [Anatomical pathology of the lymph nodes following lymphography]. PMID- 4314157 TI - [Periodicity of narcoleptic attacks and the circadian rhythm of rapid sleep]. PMID- 4314158 TI - [Acute porphyria with paralyses and stomach carcinoma]. PMID- 4314159 TI - [Contralateral involvement of cranial nerves in posterior cranial fossa tumors]. PMID- 4314160 TI - [Extensive orthostatic hypotension. Anatomical and clinical study]. PMID- 4314161 TI - [Brain tumors revealed by an acute meningeal syndrome: subarachnoid hemorrhage or septic meningitis]. PMID- 4314162 TI - Carcinogenicity testing of selected food additives by parenteral administration to infant Swiss mice. PMID- 4314163 TI - [Phosphatase activity of motor neurons in the spinal cord of rabbits during chromatolysis]. PMID- 4314164 TI - [Histochemistry of the islands of Langerhans in mammals]. PMID- 4314165 TI - Generalized muscular stiffness, fasciculations, and myokymia of peripheral nerve origin. PMID- 4314166 TI - Gluconeogenesis in the kidney cortex. Flow of malate between compartments. AB - 1. Kidney-cortex slices from starved rats were incubated with l-[U-(14)C]lactate or l-[U-(14)C]malate plus unlabelled acetate and the specific radioactivity of the glucose formed was determined. In parallel experiments the specific radioactivity of the glucose formed from [1-(14)C]acetate plus unlabelled l lactate and l-malate was determined. 2. By analytical methods the major products formed from the substrates were measured. The glucose formed was purified by paper chromatography for determination of specific radioactivity. 3. The specific radioactivity of the glucose formed from l-[U-(14)C]lactate agrees with predictions of a model based on interaction of the gluconeogenic and the oxidative pathways. 4. The specific radioactivity of the glucose formed from l-[U (14)C]malate agrees with the predicted value if rapid malate exchange between the cytosol and mitochondria is assumed. 5. The rate of malate exchange between compartments was estimated to be rapid and at least several times the rate of glucose formation. 6. The specific radioactivity of the glucose formed from [1 (14)C]acetate plus unlabelled l-lactate or l-malate agrees with the predictions from the model, again assuming rapid malate exchange between compartments. 7. Malate exchange between compartments together with reversible malate dehydrogenase activity in the mitochondria and cytosol also tends to equilibrate isotopically the NADH pool in these compartments. (3)H from compounds such as l [2-(3)H]lactate, which form NAD(3)H in the cytosol, appears in part in water; and (3)H from dl-beta-hydroxy[3-(3)H]butyrate, which forms NAD(3)H in the mitochondria, appears in part in glucose, largely on C-4. PMID- 4314168 TI - Spinal afferents to SI and SII of the rat thalamus. PMID- 4314167 TI - Interferon response of lymphocytes in disorders with decreased resistance to infections. PMID- 4314169 TI - Synaptic transmission in the degenerating lateral geniculate nucleus. An ultrastructural and electrophysiological study. PMID- 4314170 TI - Isolation of membrane-associated tumour-specific antigen from an aminoazo-dye induced rat hepatoma. PMID- 4314171 TI - Malignant and transforming activity of Rous sarcoma virus. I. Malignant effect of Rous sarcoma virus. PMID- 4314172 TI - Malignant and transforming activity of Rous sarcoma virus. II. The study of variants of Rous sarcoma virus isolated from mouse tumours. PMID- 4314173 TI - Studies on Murine Sarcoma Virus; a morphological comparison of tumorigenesis by the Harvey and Moloney strains in mice, and the establishment of tumor cell lines. PMID- 4314174 TI - Studies on group-specific antigens in tumours induced with avian tumour viruses in rats. PMID- 4314175 TI - [Benign mixed tumor of the deep lobe of the parotid gland]. PMID- 4314176 TI - Electrical transmission among neurons in the buccal ganglion of a mollusc, Navanax inermis. AB - The opisthobranch mollusc, Navanax, is carnivorous and cannibalistic. Prey are swallowed whole by way of a sudden expansion of the pharynx. The buccal ganglion which controls this sucking action was isolated and bathed in seawater. Attention was focused upon 10 identifiable cells visible on the ganglion's rostral side. Two cells were observed simultaneously, and each was penetrated with two glass microelectrodes, one for polarizing the membrane and the other for recording membrane potential variations. The coupling coefficients for direct current flow and action potentials of several identified cells were tabulated. Attenuation was essentially independent of the direction of current flow, but depended upon the relative size of the directly and indirectly polarized cells. The attenuation of subthreshold sinusoidally varying voltages increased with frequency above about 1 Hz. The coupling coefficient for spikes was lower than for DC due to greater high frequency attenuation. There is considerable similarity in the spontaneous PSP's of all cells, which is not due to the electrical coupling but to input from a common source. The 10 cells were not chemically interconnected but some were electrically connected to interneurons which fed back chemically mediated PSP's. The feedback can be negative or positive depending upon the membrane potential of the postsynaptic cell. We conclude that electrical coupling among the 10 cells plays a minor role in sudden pharyngeal contractions but that the dual electrical chemical coupling with interneurons may be important in this respect. PMID- 4314177 TI - Analysis of the neutralizing activity in nasal wash and serum following intranasal vaccinaion with inactivated type 13 rhinovirus. PMID- 4314178 TI - Late 19S rabbit antibody neutralization test for differentiating herpes simplex virus types 1 and 2. PMID- 4314179 TI - Measurement of antibodies to herpesvirus types 1 and 2 in human sera. PMID- 4314180 TI - Purification and serologic tests with adenovirus 2 virion and T antigens. PMID- 4314181 TI - The neuromyopathy of vincristine in man. Clinical, electrophysiological and pathological studies. PMID- 4314183 TI - [Lung neoplasm (mixed tumor of salivary gland type)]. PMID- 4314182 TI - The neuromyopathy of vincristine in the guinea pig. An electrophysiological and pathological study. PMID- 4314184 TI - [Quantitative analysis of serum phospholipids by means of thin-layer chromatography]. PMID- 4314185 TI - Experiences in laboratory diagnosis of parainfluenza viruses in routine medical practice. PMID- 4314186 TI - Clostridium welchii brain abscess following craniotomy for meningioma: a case report. PMID- 4314187 TI - Endogenous collagenase in periodontal disease. PMID- 4314188 TI - The epidemiology of cholera in Calcutta as noted by biotyping the isolates. PMID- 4314189 TI - A synthetic polypeptide--beta 1-24 corticotropin--in the depot form. I. Adrenocorticotropic and pituitary responsiveness following long-term intermittent administration. PMID- 4314190 TI - A synthetic polypeptide--beta 1-24 corticotropin--in the depot form. II. Clinical efficacy of intermittent therapy in asthmatic patients. PMID- 4314191 TI - [Experience with the therapy of multiple sclerosis using ACTH]. PMID- 4314192 TI - Further studies on the hypophyseal--adrenocortical response to various stressing procedures in ACTH-treated rats. PMID- 4314193 TI - The disappearance rate of corticosterone from the blood of ACTH-treated rats. PMID- 4314194 TI - Influence of pituitary hormones (ACTH and ACTH analogues) and corticosteroid on the central nervous system in rats and chicks. Electrophysiological and behavioural studies. PMID- 4314195 TI - [Anesthetic problems raised by surgical cure of langerhansian adenoma. One case]. PMID- 4314196 TI - [Agenesis of the pectoral muscle associated with congenital malformation of the hand: syndactyly and ectrodactyly]. PMID- 4314197 TI - [Pathogenic problems of the "amniotic adhesions". 2 cases]. PMID- 4314198 TI - [Electron spin resonance studies of the reaction kinetics of radiation-induced free radicals of cholesterol]. PMID- 4314199 TI - [Application of radioautography associated with immuno-enzymatic technics for the study of antigens and antibodies]. PMID- 4314200 TI - [Absence of growth stimulation of chick embryo cells infected with avian lymphomatosis virus RAV]. PMID- 4314201 TI - [Persistance of the necessity for DNA synthesis for Rous virus replication in cells preinfected by a related virus]. PMID- 4314202 TI - [Case contribution to the study of synovial sarcoma (presentation of 2 cases with foot localization)]. PMID- 4314203 TI - [Irreversible lesions of the trigeminal nerve caused by chlorinated acetylenes in two patients]. PMID- 4314204 TI - [Somnambulistic psychomotor epilepsy]. PMID- 4314205 TI - [Clinical and polyphysiographic studies in periodic narcolepsy]. PMID- 4314207 TI - [Occupational diseases of the peripheral nerves in animated cartoon artists]. PMID- 4314206 TI - [Electron microscopic myopathological findings in hypercorticism due to an ACTH active liver carcinoma]. PMID- 4314208 TI - A simplified method for the determination of vitamins D2 and D3 in water dispersible preparations by gas-liquid chromatography. PMID- 4314209 TI - [Reaction of alpha-tocopherol with 1,1-diphenyl-2-picrylhydrazyl. IV. The alpha tocopheryl-radical]. PMID- 4314210 TI - [Diagnosis of acute pericarditis in Abidjan. Apropos of 62 cases]. PMID- 4314211 TI - Stress ulcers. PMID- 4314212 TI - [Clinico-radiologic characteristics of synovial sarcoma of the extremities]. PMID- 4314213 TI - [Diagnostic value of the Kaplan-Silah angiotensin infusion test in arterial hypertension of various etiology]. PMID- 4314214 TI - [On the Krukenberg syndrome. Morphological and histochemical study]. PMID- 4314215 TI - [Experimental sleep deprivation in the normal subject]. PMID- 4314216 TI - [Effect of sensory deprivation on experimental sleep inducement]. PMID- 4314217 TI - [Trematoda from amphibians of the Ivory Coast]. PMID- 4314218 TI - Adenosine 3',5'-monophosphate, adrenocorticotropic hormone, and adrenocortical cytosol protein synthesis. AB - In cultures of mouse adrenocortical tumor cells (Sato's minimal deviation Y-1 clonal strain), the acceleration of steroid biosynthesis after exposure to adrenocorticotropic hormone or cyclic adenosine 3',5'-monophosphate is maximum within 15 to 60 minutes and precedes any significant increase in labeling of protein with [4,5-(3)H]leucine. However, when cytosol proteins are separated by acrylamidegel electrophoresis, rapid changes in the amount and labeling of several protein fractions are evident in less than 30 minutes and are no longer evident within 60 minutes. This finding supports the proposal that the effects of tropic hormones and their intracellular mediators involve rapid selective effects on protein synthesis. PMID- 4314219 TI - Phage-typing of Klebsiella strains isolated from the faeces of infants and children. PMID- 4314220 TI - An electron microscopic study of the changes in ACTH- and FSH-producing cells during development of methylandrostenediol hypertension in the rat. PMID- 4314221 TI - Lung disease in Appalachian soft-coal miners. PMID- 4314222 TI - [Adrenal glands and circadian rhythm]. PMID- 4314223 TI - [The use of synthetic ACTH in the adrenal cortex function test]. PMID- 4314224 TI - [Lumbosciatalgic syndrome caused by vertebral metastases from a recurrent mixed tumor of the submandibular gland]. PMID- 4314225 TI - [Nuclear deoxyribonucleic acid (DNA) content in rat kidney after treatment with cortisone and ACTH]. PMID- 4314226 TI - [Nuclear volume in the proximal contorted tubule of rat kidney after treatment with cortisone and ACTH]. PMID- 4314227 TI - Histochemistry of the thymus and a thymoma. PMID- 4314228 TI - The isolation of infectious bovine rhinotracheitis virus from cattle in Northern Queensland. PMID- 4314229 TI - Glutamine phosphoribosylpyrophosphate amidotransferase. Catalytic and conformational heterogeneity of the pigeon liver enzyme. PMID- 4314230 TI - Characterization of a fluorescent complex between auramine O and horse liver alcohol dehydrogenase. PMID- 4314231 TI - Exonuclease (phosphodiesterase) from the testes of Chinook salmon (Oncorhynchus tschawytscha). PMID- 4314232 TI - Formation of (+)-cis-2,3-dihydroxy-1-methylcyclohexa-4,6-diene from toluene by Pseudomonas putida. PMID- 4314233 TI - Regulation of the biosynthesis of purine nucleotides in Schizosaccharomyces pombe. I. Properties of the phosphoribosylpyrophosphate: glutamine amidotransferase of the wild strain and of a mutant desensitized towards feedback modifiers. PMID- 4314234 TI - Regulation of skeletal muscle phosphorylase phosphatase activity. I. Kinetic properties of the active and inactive forms. PMID- 4314235 TI - Regulation of skeletal muscle phosphorylase phosphatase activity. II. Interconversions. PMID- 4314236 TI - Purification and properties of clostridium welchii phospholipase C. PMID- 4314237 TI - Hydrolysis, racemization and absolute configuration of ureidoglycolate, a substrate of allantoicase. PMID- 4314238 TI - [Electron spin resonance of free radicals in x-irradiated cholesterol and 5,6 dihydrocholesterol]. PMID- 4314240 TI - [ESR studies on x-irradiated leucine salts. 3. Structure of radicals in irradiated single crystals of L-leucine, HBr and L-leucine,DBr]. PMID- 4314239 TI - Radiation effects on NADH. PMID- 4314241 TI - [Use of antibiotics in combination with antiperfringens serum in the treatment of experimental gas infection caused by Cl. perfringens in association with Escherichia coli]. PMID- 4314242 TI - Allotransplantation of joints. PMID- 4314243 TI - The localization of cytochrome c oxidase activity during mitochondrial specialization in spermiogenesis of prosobranch snails. PMID- 4314244 TI - Ultrastructural and histochemical studies on the epithelium revestment layer in the tube feet of the starfish Asterina stellifera. PMID- 4314245 TI - Interferon production by mouse peritoneal cells. PMID- 4314246 TI - Radiation, infection, and macrophage function. I. Effects of whole body radiation on dermal tuberculous lesions in rabbits: development, histology, and histochemistry. PMID- 4314247 TI - Leukemoid changes induced in germfree and conventional rats by Rous sarcoma virus. PMID- 4314248 TI - Metabolic control in isolated brown fat cells. PMID- 4314250 TI - [The use of an iodized triglyceride (lipiodol) as a test of absorption of lipids in premature infants]. PMID- 4314249 TI - A mechanism for hormonal activation of lipolysis and respiration in free brown fat cells. PMID- 4314251 TI - [Problems control of avian tumor viruses and viral vaccines]. PMID- 4314252 TI - [Activity of redox enzymes in the dog myocardium]. PMID- 4314253 TI - [Tissues of the oral cavity in hypoferric anemia]. PMID- 4314254 TI - Non-chromaffin paragangliomas. Brief review and clinical-radiological follow-up on nine cases. PMID- 4314255 TI - Cochlear damage from ototoxic antibiotics by intratympanic application. PMID- 4314256 TI - Effects of angiotensin on the autonomic nervous system. PMID- 4314257 TI - [Respiratory viruses in the etiology of acute diseases in hospitalized children]. PMID- 4314258 TI - Vestibular dysfunction in schizophrenia and childhood autism. PMID- 4314259 TI - Permissive effects of hormones on lypolysis. PMID- 4314260 TI - A night hospital program. PMID- 4314261 TI - Social clubs help prevent readmission. PMID- 4314262 TI - [The renin-angiotensin system]. PMID- 4314264 TI - Comparative morphologic and functional studies of neptunium-induced fatty livers in rats. PMID- 4314263 TI - Mediators of tissue damage in leukocyte lysosomes. X. Further studies on human granulocyte elastase. PMID- 4314265 TI - NAD biosynthesis in polymorphonuclear leucocytes of guinea-pigs. I. Nicotinic acid pathway of NAD synthesis in cell-free preparations. PMID- 4314266 TI - Plasma renin in congestive heart failure in man. PMID- 4314267 TI - [Adenovirus infections]. PMID- 4314268 TI - FSR for biologists. PMID- 4314269 TI - Immunologic distinction between infectious and serum hepatitis. PMID- 4314271 TI - Formation of virus-like particles by bone cells in mice with a high incidence of spontaneous leukemia. AB - Bone samples from potentially leukemic and leukemic mice revealed numerous 90-to 110-nanometer particles morphologically identical to murine leukemia virus. Particles were observed budding from plasma membranes of osteocytes and osteoblasts but were most numerous in osteocyte lacunae. Particles were not observed in bone samples from mice which rarely develop leukemia. PMID- 4314270 TI - [Plasmatic lipids in patients with pituitary and parasellar tumors]. PMID- 4314272 TI - [Dental manifestations in various hereditary diseases]. PMID- 4314273 TI - [The clinical picture and diagnosis of delayed radionecrosis of the brain (according to materials from megavolt roentgenotherapy of intracranial neoplasms)]. PMID- 4314274 TI - [17-ketosteroid metabolism in patients with tumors of the hypophysis in the pre- and postoperative period]. PMID- 4314275 TI - [Intra-arterial infusion of antitumor chemopreparations in treating patients with neurosurgical diseases]. PMID- 4314276 TI - ACTH or corticosteroids? A critical review of results and possibilities in the treatment of severe chronic disease. PMID- 4314277 TI - [Morphogenetic study of postaxial syndactyly provoked in rats by hadacinin. I. Analysis of anomalies in adults, fetus at term and embryos at 15, 16, and 17 days]. PMID- 4314278 TI - Haem-plane orientation in single crystal of bonito cytochrome c. PMID- 4314279 TI - [Cells producing adrenocorticotropic hormone]. PMID- 4314280 TI - [A method of isolating large fragments of myocardial fibers from adult animals]. PMID- 4314281 TI - A radioisotopic method for measuring the formation of adenosine 3',5'-cyclic monophosphate in incubated slices of brain. PMID- 4314282 TI - Reconstruction of the glycerolphosphate cycle in suspensions of rat brain mitochondria. PMID- 4314283 TI - [Experimental hematogenous metastasis of a fibrosarcoma in animals with and without spleen]. PMID- 4314284 TI - [Burkitt's lymphoma and infectious mononucleosis have a single etiological factor: the Epstein-Barr virus]. PMID- 4314285 TI - [The behavior of plasmatic corticotropin activity in subjects treated with high doses of a preparation of adrenal cortex extract]. PMID- 4314286 TI - Mycoecology on serpentine soil. PMID- 4314287 TI - [Results of the intradermal hypertension test and Hines-Brown cooling test in various types of arterial hypertension]. PMID- 4314288 TI - [Pathologic hyperlactatemia during treatment with phenformin]. PMID- 4314289 TI - [Meningioma of the clivus revealed by manipulations of the cervical rachis spine]. PMID- 4314290 TI - [Histological changes of the lymph nodes during radiant lymphography]. PMID- 4314291 TI - [Biological and clinical problems in radiant lymphography in gynecological neoplasms]. PMID- 4314293 TI - [Etiology of infectious mononucleosis]. PMID- 4314294 TI - [Study of vestibular adaptation using the pendulum test. Results in pathologic conditions]. PMID- 4314292 TI - [Viral myocarditis]. PMID- 4314295 TI - [Sleep deprivation and eye movements in patients with chronic schizophrenia]. PMID- 4314296 TI - [Study of jactatio capitis during night sleep]. PMID- 4314297 TI - [The electroencephalogram in acute necrotizing encephalitides]. PMID- 4314298 TI - [Microscopic features of species differences of the bones of man and animals. I]. PMID- 4314299 TI - [Anabolic steroids in the treatment of endocrine diseases]. PMID- 4314301 TI - [Preparation and control of variant sera for type O foot-and-mouth disease virus]. PMID- 4314302 TI - [Comparative resistance of foot-and-mouth disease virus to formalin and hydroxylamine]. PMID- 4314300 TI - [Oxygen isotope metabolism catalyzed by hydrolytic enzymes]. PMID- 4314303 TI - [The temperature of the brain]. PMID- 4314304 TI - [Analysis of different electroencephalographic cycles during sleep in 6 chronic schizophrenics; polygraphic correlations (the electrodermogram and the electromyogram)]. PMID- 4314305 TI - Sleep disturbance and serum CPK activity in acute psychosis. PMID- 4314306 TI - Sleep during alcohol intake and withdrawal in the chronic alcoholic. PMID- 4314307 TI - The effect of an interferon inducer on influenza virus. AB - The double-stranded complex of polyriboinosinic acid and polyribocytidilic acid (poly I.poly C) was shown to inhibit effectively the infection of human cells with 4 common human respiratory pathogens-influenza A2, rhinovirus 13, respiratory syncytial and parainfluenza-1 viruses. This protection was observed with levels of poly I.poly C which did not induce the release of detectable amounts of interferon. Mice could be protected from pulmonary influenza A2 infections by intranasal instillation of poly I.poly C before challenge with virus. Administration of poly I.poly C directly to the respiratory tract was found superior to systemic administration in the case of the pulmonary infection studied. PMID- 4314308 TI - Differences of plasma angiotensin concentration in rats with normal blood pressure, experimental renal and neurogenicointeroceptive hypertension. PMID- 4314309 TI - The premature deposition or lysis of glycogen in livers of fetal rats injected with hydrocortisone or glucagon. PMID- 4314310 TI - Electron spin resonance and optical studies of the interaction between NO2 and unsaturated lipid components. PMID- 4314311 TI - Steroid biosynthetic enzymes and the regulation of mammalian reproduction. PMID- 4314312 TI - [Circulation of enteroviruses in the sewage of Voronezh in 1966-1967]. PMID- 4314313 TI - [Use of solid grain sorbents for collecting air samples]. PMID- 4314314 TI - Conditions simulating metastatic lesions of the brain. Report of eight cases. PMID- 4314315 TI - Theca cell tumor of the ovary associated with pregnancy. PMID- 4314316 TI - [Erb's progressive muscular dystrophy--a generalized enzyme loss syndrome?]. PMID- 4314317 TI - [Neurologic and neuropsychic sequelae following amputation]. PMID- 4314318 TI - [The therapeutic effect of corticosteroids on the symptoms and course of multiple sclerosis]. PMID- 4314319 TI - Protection of rabbits against experimental rabies of poly I-poly C. PMID- 4314320 TI - Chemotactic factor associated with invasion of cancer cells. PMID- 4314322 TI - New light-induced EPR signal in Anacystis nidulans. PMID- 4314321 TI - Fatty acid mobilization in obese mice. PMID- 4314323 TI - Electron microscopic and histochemical counterparts of renal glomerular damage in experimental crush syndrome in white rat. PMID- 4314324 TI - Activity of certain enzymes in blood plasma and dialyzing fluid in patients with renal failure treated with peritoneal dialysis. PMID- 4314325 TI - [Glomangiosis of the lung]. PMID- 4314326 TI - Mossbauer spectroscopy of haem proteins. PMID- 4314327 TI - Magnetic resonance studies of enzyme-substrate complexes with paramagnetic probes as illustrated by creatine kinase. PMID- 4314328 TI - [Radiotherapeutic cardiomyopathy. Pathogenic mechanism due to autoantibodies]. PMID- 4314329 TI - [Semiological and radiological aspects of fractures of odontoid apophysis. 6 cases observed in 7 years in a general medicine department]. PMID- 4314330 TI - [Lumbar sympathectomy in atherosclerosis. Statistical study of a series of 106 cases]. PMID- 4314331 TI - [Trans-sexualism: respective value of the biological and psychic determinants. 2 cases]. PMID- 4314332 TI - [Retroperitoneal male chorioepithelioma, apparently primary, in reality secondary to a microscopical testicular tumor]. PMID- 4314333 TI - [Treatment of the climacteric syndrome using Dihydroequilin]. PMID- 4314335 TI - Heart glycosides in poliovirus host cell interaction. 3. Chemical structure and activity. PMID- 4314334 TI - [Comparative biochemical and immunological studies of the homogenates of normal as well as pathologically changed livers]. PMID- 4314336 TI - New selective medium for the isolation of Clostridium perfringens. PMID- 4314337 TI - Bovine infectious keratoconjunctivitis: interactions of Moraxella bovis and infectious bovine rhinotracheitis virus. PMID- 4314338 TI - Viral antibody patterns in laboratory dogs with respiratory disease. PMID- 4314339 TI - [Particle size distribution of dust from the lungs of inhabitants of areas with and without air pollution]. PMID- 4314340 TI - [Aspects of insular-like neogenesis in ductal carcinoma with highly differentiated cells in the pancreas]. PMID- 4314341 TI - Influence of peptides on the output of noradrenaline from isolated rabbit hearts. PMID- 4314342 TI - The challenge of amoebiasis: understanding pathogenic mechanisms. PMID- 4314343 TI - Histochemical differentiation of red and white muscle fibers. PMID- 4314344 TI - [State of the cardiovascular system in patients with Addison's disease]. PMID- 4314345 TI - Experimental Herpes-T infection in hamsters. PMID- 4314346 TI - [Pathogenetic considerations on the occurrence of dysplastic phenomena during diffuse interstitial pulmonary fibrosis. Report of a clinico-pathological case]. PMID- 4314347 TI - [Management of so-called cubital tunnel syndrome]. PMID- 4314348 TI - Comparison of stage four and 1-rem sleep deprivation. PMID- 4314349 TI - Reactions of the rat and hamster endocrine system to aminoglutethimide. PMID- 4314350 TI - [Giant fibroadenomyxoma or phyllodes of the breast]. PMID- 4314351 TI - [Steroid osteopathy (literature review)]. PMID- 4314352 TI - [Activity of some enzymatic systems of corticosteroidogenesis in rats during prolonged administration of various doses of ACTH]. PMID- 4314353 TI - [Comparison of histochemical reaction of the adrenal cortex of rats in response to ACTH, STH and sex hormones administration]. PMID- 4314354 TI - [Hypocorticism of therapeutic orgin. I. Iatrogenic hypocorticism. Post-cortisonic hypocorticism: mechanism, symptoms, palliation]. PMID- 4314355 TI - [Hypocorticism of therapeutic origin. II. Exploration tests of hypothalamohypophyso-adrenal axis: principle and applications]. PMID- 4314356 TI - [Hypocorticism of therapeutic origin. 3. Current survey of ACTH-therapy]. PMID- 4314357 TI - [Articular chondrocalcinosis]. PMID- 4314358 TI - [Microspherocytosis associated with factor IX deficiency]. PMID- 4314359 TI - [Several aspects of the problem of lysosomes]. PMID- 4314360 TI - [Hetero-organic antigens in regenerating liver in rats]. PMID- 4314361 TI - [Kidney and blood pressure regulation]. PMID- 4314362 TI - [Energy metabolism in the myocardium with coronary blood flow disorders]. PMID- 4314364 TI - [Consequences of disturbance of liver function on the renin-angiotensin system]. PMID- 4314363 TI - [The kidney and volume control in blood circulation]. PMID- 4314365 TI - [Modern methods of treating septic endocarditis (review of the literature)]. PMID- 4314366 TI - [Some virological and epidemiological remarks on the encephalitic syndrome with fatty degeneration of the viscera]. PMID- 4314367 TI - [Serology of Bordetella pertussis. I. Distribution of serotypes]. PMID- 4314368 TI - Distribution of a porcine adenovirus after inoculation of experimental animals. PMID- 4314369 TI - [Plaque tests with agarose overlay on Herpes simplex virus and adenovirus]. PMID- 4314370 TI - [Report on the etiology of virus diseases. 1st quarter 1968. 3]. PMID- 4314371 TI - [Deviations of a 1st order reaction in the inactivation of foot-and-mouth disease (FMS) virus with hydroxylamine]. PMID- 4314372 TI - [Continuous low pressure dialysis for concentration of biopolymers. Concentration of suspensions of foot-and-mouth disease (FMD) virus]. PMID- 4314373 TI - Pathogenesis of chronic mouse cytomegalovirus infection in submaxillary glands of C3H mice. PMID- 4314374 TI - [Copper deficiency in ruminants]. PMID- 4314375 TI - Effects of pesticides on nitrite oxidation by Nitrobacter agilis. AB - The influence of pesticides on the growth of Nitrobacter agilis in aerated cultures and on the respiration of N. agilis cell suspensions and cell-free extracts was studied. Two pesticides, aldrin and simazine, were not inhibitory to growth of Nitrobacter, but five compounds [isopropyl N-(3-chlorophenyl) carbamate (CIPC), chlordane, 1,1-dichloro-2,2-bis (p-chlorophenyl) ethane (DDD), heptachlor, and lindane] prevented growth when added to the medium at a concentration of 10 mug/ml. Whereas CIPC and eptam prevented nitrite oxidation by cell suspensions, the addition of DDD and lindane resulted in only partial inhibition of the oxidation. Heptachlor and chlordane also caused only partial inhibition of oxidation, but were more toxic with cell-free extract nitrite oxidase. None of the pesticides inhibited the nitrate reductase activity of cell free extracts, but most caused some repression of cytochrome c oxidase activity. Heptachlor was the most deleterious compound. PMID- 4314376 TI - Hydrolysis of conjugated bile acids by cell-free extracts from aerobic bacteria. AB - By means of an aerobic enrichment culture technique, several bacteria that hydrolyze conjugated bile acids and modify the formed deconjugates were isolated from feces of man, rat, and chicken and from soil. Hydrolase activity was intracellular and extractable, and the yield of the enzymes was increased by adding the conjugated bile acids to the culture media. The hydrolase from bacterium of human origin was stable, having a pH optimum at about 7.0. All bile acid conjugates were hydrolyzed linearly as a function of time. PMID- 4314377 TI - Pathogenicity of Clostridium perfringens for germ-free guinea pigs after oral ingestion. AB - Germ-free guinea pigs died with signs and lesions of acute enterotoxemia after oral ingestion of C. perfringens types B, C, D, and E. The signs and lesions observed resembled those seen in acute enterotoxemia of sheep and cattle and the naturally occurring disease seen in "ex-germ-free" guinea pigs. C. perfringens type A was found to be innocuous. Conventional guinea pigs did not become ill after ingestion of any of the five toxigenic types. PMID- 4314378 TI - Comparative poliovirus permeability of silver, polycarbonate, and cellulose membrane filters. AB - Three types of filters, silver, polycarbonate, and cellulose, were evaluated for permeability toward poliovirus suspended in water, salt-containing, and proteinaceous solvents. The ability of virus to pass through cellulose filters depended on the suspending medium; virus did not pass through cellulose filters in either water or salt solution, whereas the use of protein solutions increased filterability. The virus permeability of both the silver and polycarbonate filters was independent of the suspending medium. Apparently, pore size alone determined their permeability toward poliovirus, and electrostatic forces between filters and the particles being filtered did not appear to play a significant role. Both the silver and polycarbonate filters appear to be promising tools for the separation of viruses from contaminating bacteria and fungi. PMID- 4314380 TI - Growth from spores of Clostridium perfringens in the presence of sodium nitrite. AB - The method by which sodium nitrite may act to prevent germination or outgrowth, or both, of heat-injured spores in canned cured meats was investigated by using Clostridium perfringens spores. Four possible mechanisms were tested: (i) prevention of germination of the heat-injured spores, (ii) prior combination with a component in a complex medium to prevent germination of heat-injured spores, (iii) inhibition of outgrowth of heat-injured spores, and (iv) induction of germination (which would render the spore susceptible to thermal inactivation). Only the third mechanism was effective with the entire spore population when levels of sodium nitrite commercially acceptable in canned cured meats were used. Concentrations of 0.02 and 0.01% prevented outgrowth of heat-sensitive and heat resistant spores, respectively. Nitrite-induced germination occurred with higher sodium nitrite concentrations. PMID- 4314381 TI - [Decomposition of collagen in experimental silicosis following treatment with polyvinylpyridine-N-oxide in dependence on the dosage]. PMID- 4314379 TI - Serratia marcescens: biochemical, serological, and epidemiological characteristics and antibiotic susceptibility of strains isolated at Boston City Hospital. AB - The biochemical, serological, and epidemiological characteristics of 95 strains of Serratia marcescens isolated at the Boston City Hospital were examined. Several strains were shown to be endemic, and the majority of isolates were cultured from urine or respiratory secretions. Serratia species were highly resistant to polymyxin B and the cephalosporins, and various proportions were also resistant to other antibiotics including kanamycin, but all of the isolates were sensitive to gentamicin. The appearance of resistance to kanamycin and nalidixic acid among endemic strains was demonstrated. The nosocomial nature of Serratia infections, particularly those involving the urinary tract, was confirmed. Many clinical bacteriology laboratories currently fail to identify the nonpigmented strains. PMID- 4314382 TI - Revised data on (35S)-atractyloside binding to mitochondrial membranes. PMID- 4314383 TI - Uncoupling of oxygen activation from hydroxylation in a bacterial salicylate hydroxylase. PMID- 4314384 TI - Stimulation of lac mRNA synthesis by cyclic AMP in cell free extracts of Escherichia coli. PMID- 4314385 TI - The interactions of copper and a3 in cytochrome oxidase. PMID- 4314386 TI - Evidence of mitochondrial synchrony in synchronous cell cultures of yeast. PMID- 4314387 TI - Inactivation and repression by ammonium of the nitrate reducing system in chlorella. PMID- 4314388 TI - The effect of catabolite repression and of cyclic 3',5' adenosine monophosphate on the translation of the lactose messenger RNA in Escherichia coli. PMID- 4314389 TI - Acylation of lysine and of arginine-rich histones with carbamyl phosphate and 1,3 diphosphoglycerate. PMID- 4314391 TI - Studies on the nonspecific phosphodiesterase activity of splenic acid deoxyribonuclease. PMID- 4314390 TI - Abscisic acid induced changes in nucleotide composition of rapidly labelled RNA species of pear embryos. PMID- 4314392 TI - Absorption spectrophotometry of perfused rat liver applied to fructose-induced inhibition of respiration. PMID- 4314394 TI - Somatomotor inhibition and excitation by forebrain stimulation during sleep and wakefulness: orbital cortex. PMID- 4314395 TI - Responses of neurons in the raphe nuclei to serotonin, norepinephrine and acetylcholine and their correlation with an excitatory synaptic input. PMID- 4314393 TI - Co-ordination between membrane phospholipid synthesis and accelerated biosynthesis of cytoplasmic ribonucleic acid and protein. AB - 1. The rate of synthesis of membrane phospholipid was studied in rat liver and seminal vesicles by following the incorporation of [(32)P]orthophosphate, [(14)C]choline and [(14)C]glycerol. Particular emphasis was laid on the endoplasmic reticulum, which was fractionated into smooth microsomal membranes, heavy rough membranes, light rough membranes and free polyribosomes. 2. Phospholipid labelling patterns suggested a heterogeneity in the synthesis and turnover of the different lipid moieties of smooth and rough endoplasmic membranes. The major phospholipids, phosphatidylcholine and phosphatidylethanolamine, were labelled relatively rapidly with (32)P over a short period of time whereas incorporation of radioisotope into the minor phospholipids, sphingomyelin, lysolecithin and phosphatidylinositol proceeded slowly but over a longer period of time. 3. The incorporation of orotic acid into RNA and labelled amino acids into protein of the four submicrosomal fractions was also studied. 4. Rapid growth of the liver was induced by the administration of growth hormone and tri-iodothyronine to hypophysectomized and thyroidectomized rats and by partial hepatectomy. Growth of seminal vesicles of castrated rats was stimulated with testosterone propionate. 5. The rate of labelling of membrane phospholipids was enhanced in all major subcellular particulate fractions (nuclear, mitochondrial and microsomal) during induced growth. However, it was in the rough endoplasmic reticulum that the accumulation of phospholipids, RNA and protein was most marked. The effect of hormone administration was also to accelerate preferentially the labelling with (32)P of sphingomyelin relative to that of phosphatidylcholine or phosphatidylethanolamine. 6. Time-course analyses showed that, in all four growth systems studied, the enhancement of the rate of membrane phospholipid synthesis coincided with the rather abrupt increase in the synthesis of RNA and protein of the rough endoplasmic reticulum. Growth hormone and tri-iodothyronine administered to hypophysectomized rats had additive effects in all the biosynthetic processes. The latent period of action of each hormone was maintained so that two waves of proliferation of endoplasmic reticulum occurred if the hormones were administered simultaneously. 7. It is concluded that there is some mechanism in the cell that tightly co-ordinates the formation of membranes, especially those of the endoplasmic reticulum, when an increased demand is made for protein synthesis. PMID- 4314396 TI - On the interaction of picrotoxin with GABA and glycine in the spinal cord. PMID- 4314397 TI - Labyrinthine and neck reflexes recorded from spinal single motoneurons in the cat. PMID- 4314398 TI - Amoebiasis cutis following surgical drainage of a large hepatic, subphrenic and perinephric abscess. PMID- 4314399 TI - Rhinovirus infections in Glasgow in 1962-66. PMID- 4314400 TI - [Comparative action of estrogens and androgens on adrenal modifications induced by thyroxine administration]. PMID- 4314401 TI - [On a particular aspect of the agranular endoplasmic reticulum in interrenal cells of Salamandra salamandra L. stimulated by endogenous ACTH]. PMID- 4314402 TI - Increase of serotonin in the adductors of Anodonta cygnea L. (Pelecypoda) relaxed by nerve stimulation and in relation to the periodic activity. PMID- 4314403 TI - A mixed longitudinal study on skeletal maturation in healthy Finnish children aged 1 to 5 years. PMID- 4314404 TI - Prevalence and duration of postnatally acquired human cytomegalovirus infection. PMID- 4314405 TI - Characteristics of transmission ilure in the squid stellate ganglion: a study of a simple habituating system. PMID- 4314406 TI - Control of prolactin release and its role in color change in the teleost Gillichthys mirabilis. PMID- 4314407 TI - A re-investigation of evidence for cholinergic neuromuscular transmission in insects. PMID- 4314408 TI - [Demonstration of dehydrogenase activity of avian fibroblasts transformed in vitro by Rous sarcoma virus]. PMID- 4314409 TI - Properties of temperature-sensitive mutants of the KENYA 3/57 strain of foot-and mouth disease virus. PMID- 4314411 TI - [Serological studies of Japanese encephalitis (hemagglutination-inhibition, complement fixation and neutralizing antibody response tests in patients with Japanese encephalitis]. PMID- 4314410 TI - Inhibition of poliovirus RNA synthesis by supraoptimal temperatures. PMID- 4314412 TI - [Electron microscope localization of the activity of certain nucleases in ultrathin serial sections]. PMID- 4314413 TI - Effect of fasting and of phenobarbital on the distribution and latency of glucose 6-phosphatase in microsomal sub-fractions of rat liver. PMID- 4314414 TI - Plasma corticosterone and circadian rhythm in generation of the Arneil-Dekanski factor. PMID- 4314415 TI - Interrelations of some pituitary hormones. PMID- 4314416 TI - Shared viral antigen of mammalian leukaemia viruses. PMID- 4314417 TI - The carrier state in cattle in foot-and-mouth disease. PMID- 4314418 TI - Transitory liver antigens and primary hepatoma in man and rat. PMID- 4314419 TI - Experiences in a long-term cultivation of own human diploid cell strains in synthetic medium with growth promoting proteins. PMID- 4314420 TI - Experience with production of attenuated poliovirus in monkey kidney and WI-38 cells. PMID- 4314421 TI - Utilization and control of BHK cells in inactivated foot-and-mouth disease vaccine production. PMID- 4314423 TI - Enzymatic cell-virus relations: lactate dehydrogenase and glutamic-oxaloacetic transaminase in normal and infected tissue cultures. PMID- 4314422 TI - Behaviour of enzyme systems in cercopithecus and rhesus kidney cells in consequence of SV40 virus action. PMID- 4314424 TI - The production of large gnotobiotic animals and their use in the preparation of virus reference sera. PMID- 4314425 TI - Enhancement of viral infectivity with DEAE-dextran: application to development of vaccines. PMID- 4314426 TI - The preparation of viral vaccines containing purified extracted antigens. PMID- 4314427 TI - Testing of vaccines for avian leukosis viruses. PMID- 4314428 TI - Semicontinuous cultivation of Bordetella pertussis. PMID- 4314430 TI - The relevance of agglutinogenic types of Bordetella pertussis in the assay of pertussis vaccines. PMID- 4314429 TI - Animal cell strains as substitutes for primary monkey cultures in testing Salk and other inactivated vaccines for persistent viruses. PMID- 4314431 TI - The role of the serologic type in experimental immunity against B. Pertussis. PMID- 4314432 TI - Experiences with a new combined vaccine against B. parapertussis, Diphtheria, tetanus and B. pertussis employed in a field trial in Prague 10. PMID- 4314433 TI - SV 40 replication in presence of monkey kidney antibodies. PMID- 4314434 TI - The use of an in vitro test for the estimation of presence of the specific tumor antigen of the transplantation type induced by SV 40 virus. PMID- 4314435 TI - Studies with SV 40--adeno 7 hybrid virus. PMID- 4314436 TI - Neutralizing antibodies to simian virus 40 (SV 40) in human sera. PMID- 4314437 TI - Adventitious agents in African green monkey kidney tissue cultures used for the production of live attenuated poliomyelitis vaccine. PMID- 4314438 TI - Presence of viral genome in Chinese hamster embryonic cell transformed in vitro with Bryan strain of Rous sarcoma virus (B-RSV). PMID- 4314439 TI - Establishment and maintenance of a specific pathogen free (SPF) flock of white leghorn chickens. PMID- 4314440 TI - Distinctive features and comparative value of the genetic markers defining the behaviour of poliovirus towards different selective inhibitors. PMID- 4314441 TI - Problems associated with the study of spontaneous mutation towards guanidine resistance in poliovirus. PMID- 4314442 TI - A consideration of the cell substrates used in human virus vaccine preparation. PMID- 4314443 TI - Enzyme activity during the growth and aging of human cells. PMID- 4314444 TI - Relative stability of the characteristic sulfur and doublet resonances in x irradiated native proteins as measured with ESR. PMID- 4314445 TI - 6oCo gamma-radiolysis of liquid formamide: gaseous and high-boiling stable products. PMID- 4314446 TI - Late effects of x-irradiation in chemically protected mice: alteration of tumor incidence after AET-treatment. PMID- 4314447 TI - EPR of fast repair reactions by sulfhydryl and disulfide compounds in aqueous solutions. PMID- 4314448 TI - Current use of hypnotic drugs--is it rational? PMID- 4314449 TI - Selective tosylation of adenosine 5'-monophosphate. PMID- 4314450 TI - [Investigations with magnetic circular dichroism. XI. Adenosine cyclonucleoside]. PMID- 4314451 TI - [Physiopathology of the kidney in congestive heart insufficiency]. PMID- 4314452 TI - The stapediovestibular joint: normal structure and pathogenesis of otosclerosis. PMID- 4314453 TI - Three dimensional observation of the inner ear with the scanning electron microscope. PMID- 4314454 TI - The evolution of Cushing's syndrome as a clinical entity. PMID- 4314455 TI - Ectopic hormone production in cancer and its implication for basic research on abnormal growth. PMID- 4314456 TI - [Embryonal sarcoma in children (6 cases)]. PMID- 4314457 TI - Surgical consideration in disorders of the horizontal and vertical portions of the facial nerve. PMID- 4314458 TI - [Optical and electron microscopy study of a case of acute necrosing encephalitis]. PMID- 4314459 TI - ["Mixed tumors" and uterine sarcoma]. PMID- 4314460 TI - [Mixed malignant mesodermal heterologous tumor of the cervix uteri]. PMID- 4314462 TI - The intracellular distribution of the latent hexokinase in brain. PMID- 4314463 TI - Influence of gibberellic acid on the incorporation of 8-14C adenine into adenosine 3',5'-cyclic phosphate in barley aleurone layers. PMID- 4314461 TI - Stimulation by N6,O2'-dibutyryl adenosine 3',5'-cyclic-phosphate of amino acid transport, protein synthesis, and chondroitin sulfate synthesis in embryonic bone in vitro contrasted with the effects of thyroid hormones. PMID- 4314464 TI - The enzymatic synthesis of N-methylalanine. PMID- 4314465 TI - The metabolism of adenosine 3',5'-cyclic phosphate. II. Some properties of adenosine-3',5'-cyclic-phosphate phosphodiesterase from the rat kidney. PMID- 4314466 TI - The effect of light upon ribonuclease activity of etiolated Lupinus albus hypocotyls. PMID- 4314468 TI - The localization of the hemoglobin messenger RNA on the 40-S ribosomal subunit of rabbit reticulocyte polysomes. PMID- 4314467 TI - The metabolism of adenosine 3',5'-cyclic phosphate. I. Method for the determination of adenyl cyclase and some properties of the adenyl cyclase isolated from the rat kidney. PMID- 4314469 TI - Waldenstrom's macroglobulinemia: correlation between expanded plasma volume and increased serum viscosity. PMID- 4314470 TI - The use of polyoma virus for studies on genetic regulation in mammalian cells. PMID- 4314471 TI - [Control serums]. PMID- 4314473 TI - Effects of hypophysectomy and salinity change on plasma cortisol concentration in the Japanese eel, Anguilla japonica. PMID- 4314472 TI - [Age dependent changes in the activity of lysosomal enzymes (Glycosaminoglycan hydrolases) in human serum and organs]. PMID- 4314474 TI - Control of deoxyribonucleic acid and ribonucleic acid synthesis in pyrimidine limited Escherichia coli. AB - The effects of pyrimidine limitation on chromosome replication and the control of ribosomal and transfer ribonucleic acid syntheses were investigated. Chromosome replication was studied by autoradiography of (3)H-thymine pulse-labeled cells. Pyrimidine limitation did not affect the fraction of cells incorporating radioactive thymine during a short pulse, indicating that when growth is limited by the supply of pyrimidine, the time required for chromosome duplication increases in proportion to the time required for cell duplication. Control of ribosomal RNA and transfer RNA syntheses was examined by chromatographing cell extracts on methylated albumin kieselguhr columns. When growth was controlled by carbon-nitrogen limitation, the ratio of tRNA to total RNA remained roughly constant at growth rates above 0.5 doublings per hour. During pyrimidine limitation, however, the control of rRNA synthesis was apparently dissociated from the control of tRNA synthesis: the ratio of tRNA to total RNA increased as the growth rate decreased. PMID- 4314475 TI - Stimulation of galactokinase synthesis in Escherichia coli by adenosine 3',5' cyclic monophosphate. AB - Adenosine 3',5'-cyclic monophosphate (cyAMP) stimulates the rate of synthesis of galactokinase in glycerol-grown Escherichia coli both when production of the enzyme is induced by d-fucose and when it is repressed by glucose in the presence of inducer. cyAMP also stimulates the synthesis of galactokinase in constitutive strains B78A (R(-)) and R10 (O(c)), and overcomes the transient repression of galactokinase synthesis caused by glucose. PMID- 4314476 TI - Masking of Bacillus megaterium KM membrane reduced nicotinamide adenine dinucleotide oxidase and solubilization studies. AB - Solubilization of a reduced nicotinamide adenine dinucleotide (NADH)-2,6 dichlorophenol indophenol (DCIP) oxidoreductase associated with the membrane NADH oxidase system of Bacillus megaterium KM was effected by treatment with 0.2% sodium deoxycholate, 8 m urea, or buffer (pH 9.0) in the presence of ethyl enediaminetetraacetate. These treatments inactivated membrane NADH oxidase. It was found that membrane NADH oxidase and NADH-DCIP oxidoreductase were masked in membranes. Several procedures, including brief sonic oscillation, treatment with 0.05% deoxycholate, prolonged stirring at 4 C with 10% glycerol, and washing in the absence of Mg(2+), unmasked the oxidase and oxidoreductase activities. It was necessary to study the masking and unmasking of these activities to quantitate adequately the effects of solubilization procedures. Further information on the localization of oxidase and oxidoreductase in subcellular fractions and the effects of electron transport inhibitors on NADH oxidation was also obtained. PMID- 4314477 TI - Endonuclease from Micrococcus luteus which has activity toward ultraviolet irradiated deoxyribonucleic acid: purification and properties. AB - An endonuclease purified approximately 3,200-fold from Micrococcus luteus is active on native ultraviolet-irradiated deoxyribonucleic acid (DNA), but is inactive on unirradiated native or denatured DNA and has no activity toward irradiated denatured DNA. The major type of lesion for the nucleolytic activity is the cyclobutane pyrimidine dimer. The enzyme makes a number of single-strand breaks approximately equal to the number of dimers, but dimers are not excised. This endonuclease-a small molecular weight protein-therefore has all the attributes hypothesized for the first enzyme in the sequential steps in repair of DNA in vivo. Another paper shows that the endonuclease is able to reactivate ultraviolet-irradiated transforming DNA. PMID- 4314478 TI - Endonuclease from Micrococcus luteus which has activity toward ultraviolet irradiated deoxyribonucleic acid: its action on transforming deoxyribonucleic acid. AB - An endonuclease purified from Micrococcus luteus makes single-strand breaks in ultraviolet (UV)-irradiated, native deoxyribonucleic acid (DNA). The purified endonuclease is able to reactivate UV-inactivated transforming DNA of Haemophilus influenzae, especially when the DNA is assayed on a UV-sensitive mutant of H. influenzae. After extensive endonuclease action, there is a loss of transforming DNA when assayed on both UV-sensitive and -resistant cells. The endonuclease does not affect unirradiated DNA. The results indicate that the endonuclease function is involved in the repair of biological damage resulting from UV irradiation and that the UV-sensitive mutant is deficient in this step. We interpret the data as indicating that the various steps in the repair of DNA must be well coordinated if repair is to be effective. PMID- 4314479 TI - Chromatography of microbial lipids by centrifugation through microparticulate gel. AB - An improved apparatus and a procedure are described by which the migration of sample components in column chromatography is accelerated by centrifugal force, thereby making it possible to use beds of densely packed gel prepared with ultrafine silica. This technique was used to resolve components of certain lipid mixtures where other methods have failed, and it has been found generally useful as an adjunct to other methods for the fractionation of lipids. Biologically active phosphoglycolipids from Mycobacterium tuberculosis and a phosphatidylglycerol-like substance from Mycoplasma pneumoniae which formed single spots on thin-layer chromatographic plates were each found to contain a major and several minor components by centrifugal chromatography. The method enabled us to isolate individual components of Wax D from M. tuberculosis rather than a spectrum of components. Minor components were resolved which, although present in insufficient quantity to influence results of chemical analyses, may be responsible for biological activity. The apparatus provides an essentially closed system which reduces highly volatile solvents to minimal evaporation during the chromatographic process. Samples are applied in solution and are not allowed to dry on the columns until after separation has been achieved. Consequently, polar, labile microbial lipids can be resolved without the use of harsh reagents which destroy some of their properties. Single components may be harvested by cutting and removing appropriate segments of the larger chromatograms or by eluting them from the columns. PMID- 4314481 TI - Relationship between phospholipid biosynthesis and the efficiency of the arsenate transport system in yeasts. AB - In studying the possibility that phosphoinositides which formed complexes with arsenic were involved in the arsenate transport system of yeasts, a comparative study of the phospholipid composition and metabolism was carried out both in Saccharomyces carslbergensis and in its arsenate-adapted variant, which showed a deficient inflow of arsenate. It was found that the lipid composition of the two organisms was quite similar, the main classes of phospholipids being phosphatidylcholine, phosphatidylethanolamine, and phosphoinositides. The only difference was a 1.5- to 2-fold increase in the proportion of inositides in the arsenate-adapted cells. When the transport of arsenate became inactivated in the nonadapted yeasts after a 30- to 60-min exposure to 10(-2)m arsenate, an increment of inositides of 29 to 50% over the original level was also detected. A study of the incorporation of radioactivity from uniformly labeled (14)C-maltose and from (32)P-orthophosphate ((32)P(i)) demonstrated a decreased rate of lipid biosynthesis in the arsenate-adapted cells as compared to the normal nonadapted ones. The turnover of the phosphate in phospholipids demonstrated no turnover in phosphatidylcholine and phosphatidylethanolamine, and a slow turnover in phosphoinositides. It could be inferred that a normal rate of phospholipid (phosphoinositides) biosynthesis is necessary to have a normal arsenate uptake and that inositide accumulation impairs both the mechanism responsible for the uptake and accumulation of arsenate and the rate of lipid biosynthesis. No differences were found in the deoxyribonucleic acid or protein content of the two types of cells. Also, the arsenate-adapted cells, once freed of external arsenate, showed an increased uptake of (32)P(i) from low external concentrations of phosphate (10(-6) to 10(-8)m, 10-fold over that observed in AsS cells). These results are indicative of independent behavior in phosphate and arsenate transport systems. PMID- 4314480 TI - D-glucaric acid and galactaric acid catabolism by Agrobacterium tumefaciens. AB - Cell-free extract (crude extract) of Agrobacterium tumefaciens grown on d glucuronate or d-glucarate converts d-glucarate and galactarate to a mixture of 2 keto-3-deoxy- and 4-deoxy-5-keto-d-glucarate. These compounds are then converted by partially purified crude extract to an intermediate tentatively identified as 2,5-diketoadipate. The same enzyme preparation further decarboxylates this intermediate to alpha-ketoglutarate semialdehyde, which is subsequently oxidized in a nicotinamide adenine dinucleotide-dependent reaction to alpha-ketoglutaric acid. Since A. tumefaciens converts d-glucuronic acid to d-glucarate, a pathway from d-glucuronate to alpha-ketoglutarate in A. tumefaciens was determined. PMID- 4314482 TI - Kinetics of the biosynthesis of phospholipids in neurons and glial cells isolated from rat brain cortex. PMID- 4314483 TI - Relationships between energy reserves and function in rat superior cervical ganglion. PMID- 4314484 TI - Levels of metabolites and production of glucose in the lamprey brain. PMID- 4314485 TI - Secondary tumors of the kidney. PMID- 4314486 TI - Intravenous nalidixic acid in urogenital sepsis: report of 25 courses. PMID- 4314487 TI - Lipid and fatty acid composition of brown adipose tissue in rabbit. PMID- 4314489 TI - Chronic effects of trichloroethylene exposure. PMID- 4314488 TI - Tyzzer's disease syndrome in laboratory rats treated with adrenocorticotropic hormone. PMID- 4314491 TI - Viral hepatitis: recent studies of etiology. PMID- 4314490 TI - [Level of spontaneous and provoked values of corticosteroids in schizophrenia]. PMID- 4314492 TI - [Amnesic episodes (transient global amnesia). (Clinical study based on 33 unpublished cases)]. PMID- 4314493 TI - [Surgical possibilities in coronopathy]. PMID- 4314494 TI - [Primary mediastinal seminoma]. PMID- 4314495 TI - [Gentamicin in urology]. PMID- 4314496 TI - [Alcoholic hemochromatosis: anatomo-clinical study]. PMID- 4314497 TI - [Drowned man's lung]. PMID- 4314498 TI - [Diagnosis and treatment of diffuse intravascular coagulation]. PMID- 4314499 TI - [Various frequent disorders in minor sport traumatology: sprains, tendinitis and pulled muscles]. PMID- 4314500 TI - [Acute isolated hepatomegalic form of Hodgkin's disease]. PMID- 4314501 TI - [Injurious effect of continuous electric current on transplanted hepatomas in mice]. PMID- 4314502 TI - The effect of phleomycin on poliovirus RNA replication. PMID- 4314503 TI - Guanidine inhibition of poliovirus: a dependence of viral RNA synthesis on the configuration of structural protein. PMID- 4314504 TI - Synthesis of the RNA of RNA-containing tumor viruses. I. The interval between synthesis and envelopment. PMID- 4314505 TI - Strain-specific antigen of the avian leukosis sarcoma virus group. I. Isolation and immunological characterization. PMID- 4314506 TI - The structural proteins of Mengo virus variants. PMID- 4314507 TI - Synthesis of the virus-specific proteins of a conditionally lethal mutant of poliovirus under nonpermissive conditions. PMID- 4314508 TI - Characterization of a temperature-sensitive mutant of polyoma virus. PMID- 4314509 TI - Dynamics of poliovirus-specific RNA synthesis and the effects of inhibitors of virus replication. PMID- 4314510 TI - Concentration and purification of vesicular stomatitis virus by polyethylene glycol "precipitation". PMID- 4314511 TI - Protection of enteroviruses against heat inactivation by sulfhydryl-reducing substances. PMID- 4314512 TI - Characterization of abnormal DNA formed in polyoma virus-infected cells. PMID- 4314513 TI - Immune responses to H particles of poliovirus. PMID- 4314514 TI - Partial purification of the Epstein-Barr virus and some properties of its DNA. PMID- 4314515 TI - [Clinical aspects and diagnosis of adenoviral diseases]. PMID- 4314516 TI - [Differential diagnosis of acute respiratory diseases]. PMID- 4314517 TI - [A study of adenoviruses circulating among the population and their role in certain diseases]. PMID- 4314519 TI - Hygienic guide series. Hydrogen cyanide. PMID- 4314518 TI - [Allergic manifestations of colloidal cancer of the stomach]. PMID- 4314520 TI - Effects of the intrauterine contraceptive device on endometrial enzyme and carbohydrate histochemistry. PMID- 4314521 TI - Arrhenoblastoma of the ovary. Presentation of a case report and a discussion of the differential diagnosis. PMID- 4314522 TI - Rapid eye movement (REM) sleep in ophthalmic patients. PMID- 4314523 TI - Melanocyte and Langerhans cell population of the cornea and limbus in the albino animal. PMID- 4314524 TI - Effect of BCG on lymphatic lung clearance of dusts with different fibrogenicity. An experimental study on rats. PMID- 4314525 TI - Short-term changes in sleep patterns on arrival at the South Polar Plateau. PMID- 4314527 TI - Primary malignant and benign tumors of the duodenum. A study of 18 cases stressing the clinical and roentgenographic features. PMID- 4314526 TI - Long-term changes in sleep patterns in men on the South Polar Plateau. PMID- 4314528 TI - Hyperpigmentation due solely to increased plasma beta-melanotropin. PMID- 4314529 TI - Autonomic control of the peripheral vascular system. PMID- 4314530 TI - Three hydrolysis methods for 17-ketosteroid sulfates compared by colorimetric and gas-liquid chromatographic analyses. PMID- 4314531 TI - Lactic dehydrogenase inhibitors in NAD. PMID- 4314532 TI - Transplantation of a pancreatic insulinoma into an insulin-resistant patient with juvenile diabetes. PMID- 4314533 TI - The effect of sleep on electroencephalographic abnormalities at a distance from the lesion; an all-night study of 30 cases. PMID- 4314535 TI - Correlation of clinical, parasitological, and serological data of individuals infected with Entamoeba histolytica. PMID- 4314534 TI - Influence of adrenocorticotropin, cortisone, aspirin, and phenylbutazone on the rate of exfoliation and the rate of renewal of gastric mucosal cells. PMID- 4314536 TI - Gastric secretion in duodenal ulcer, with particular reference to the diagnosis of Zollinger-Ellison syndrome. PMID- 4314537 TI - Experimental acute and chronic viral hepatitis. Effect of antithymocyte globulin. PMID- 4314539 TI - An electron nuclear double resonance and electron spin resonance study of semiquinones related to vitamins K and E-1a. PMID- 4314538 TI - Plasma renin activity and blood pressure before and after renal denervation. PMID- 4314540 TI - A paramagnetic monomeric molybdenum(V)-cysteine complex as a model for molybdenum enzyme interaction. PMID- 4314541 TI - A geriatric day ward in an English hospital. PMID- 4314542 TI - Action of a toxic glycolipid of Corynebacterium diphtheriae on mitochondrial structure and function. AB - The toxicity for mice of the cord factor of Cornebacterium diphtheriae, trehalose 6,6'-dicorynomycolate, was studied. The diphtherial cord factor showed a delayed lethal toxicity for mice; the median lethal dose was 120 mug. Mouse liver mitochondria were disrupted in vivo under the toxic action of the diphtherial cord factor into fragments deficient in both respiration and phosphorylation. The site of metabolic defect in the mitochondrial electron transport system was located at the region prior to the level of cytochrome c in the livers of cord factor-intoxicated mice. These effects of the diphtherial cord factor on the host cell mitochondria were essentially similar to those of the cord factor of Mycobacterium tuberculosis, trehalose-6,6'-dimycolate. PMID- 4314543 TI - Purificationa and properties of a fructose-1,6-diphosphate-activated lactate dehydrogenase from Streptococcus faecalis. AB - An l-(+)-lactate dehydrogenase was purified approximately 35-fold from crude extracts of Streptococcus faecalis. The purified enzyme had an absolute and specific requirement for fructose-1,6-diphosphate (FDP) for catalytic activity. The concentration of FDP required for 50% maximal activity was about 0.045 mm. The activator was bound to the enzyme more effectively at pH 5.8 than it was at a neutral or alkaline pH. Activation appeared to involve a conformational change in the enzyme which made the substrate and coenzyme sites more accessible to the respective reactants. Among the evidence supporting this hypothesis was the fact that FDP lowered significantly the apparent K(m) for both pyruvate and reduced nicotinamide adenine dinucleotide. Moreover, the enzyme, which was quite heat stable in the absence of any of the reactants, was rendered heat labile by FDP. PMID- 4314545 TI - D-apiose reductase from Aerobacter aerogenes. AB - A strain of Aerobacter aerogenes PRL-R3 has been isolated which utilizes d-apiose as its sole source of carbon. A new enzyme, d-apiose reductase, was discovered in this strain. The enzyme was not present when the strain was grown on d-glucose. d Apiose reductase catalyzes the nicotinamide adenine dinucleotide-dependent interconversion of d-apiose and d-apiitol. The enzyme is specific for d-apiose and d-apiitol, with a few possible exceptions. The K(m) for d-apiose is 0.02 m. The K(m) for d-apiitol is 0.01 m. The enzyme is almost completely specific for the reduced and oxidized forms of nicotinamide adenine dinucleotide. When cell free extracts were centrifuged at 100,000 x g for 1 hr, the enzyme remained in solution. Optimal activity for the reduction of d-apiose was obtained at pH 7.5 in glycylglycine buffer, whereas for the oxidation of d-apiitol it was obtained at pH 10.5 in glycine buffer. Enzymatic reduction of d-apiose was not appreciably affected by the presence of 0.02 m ethylenediaminetetraacetate. Paper chromatography and specific spray reagents were used to identify d-apiitol and d apiose as the products of this reversible reaction. d-Apiose and d-apiitol did not serve as substrates for ribitol dehydrogenase and d-arabitol dehydrogenase from A. aerogenes PRL-R3. PMID- 4314544 TI - Correlation of bacteria lipid composition with antibiotic resistance. AB - The correlation of bacterial lipid composition with antibiotic resistance was investigated with particular emphasis on those organisms in which resistance may be related to membrane or envelope structure or function, as in resistance to tetracyclines and polymyxin. Chloroform-methanol-extractable lipids, phosphatidyl ethanolamine fractions, and both fatty acids of these lipid fractions and total fatty acids were studied by using thin-layer chromatography, gas chromatography, and infrared spectroscopy. Consistent quantitative differences were found between the fatty acid compositions of sensitive and resistant strains. Most notable was the fact that, in gram-negative organisms, resistant strains showed decreases in cyclopropane acids as compared with sensitive strains. These changes were found to be inherent in the strains and not due to growth stage or culture age. No significant qualitative differences were noted. In contrast, no such variation in fatty acid content was observed in penicillin-sensitive and resistant strains of gram-positive cocci. As significant alterations of fatty acid composition were noted in gram-negative strains resistant to antibiotics, we suggest that resistance is correlated to membrane or envelope lipid composition. PMID- 4314546 TI - The possible mediation by cyclic AMP of parathyroid hormone-induced stimulation of mitotic activity and deoxyribonucleic acid synthesis in rat thymic lymphocytes. PMID- 4314547 TI - Behavior of virus in malignant degeneration of skin lesion in epidermodysplasia verruciformis. PMID- 4314548 TI - [Urinary pyrophosphate and hydroxyproline in bone tumors]. PMID- 4314549 TI - Sarcomas of the calvaria; surgical experience with 14 patients. PMID- 4314550 TI - Comparison of transformation and T antigen induction in human cell lines. AB - Skin fibroblast cultures were established from eight individuals. These cell cultures, together with WI-38 cells, were examined for susceptibility to transformation by SV40 virus. Four transformation-susceptible cell lines (TS), established from patients with Down's syndrome, were found to be three to four times more susceptible to transformation than transformation-resistant cell lines (TR) from normal individuals. TR and TS cell lines were compared for their susceptibility to induction of SV40 T antigen. For dividing cells T antigen was detected in a higher percentage of TS cells than TR cells. For nondividing cells, the reverse was found; T antigen was detected in 10-fold more cells of the TR lines than in cells of the TS lines. Similar results were obtained after infection of cells with CELO virus. Titration of vaccinia virus and influenza virus A2/Scotland/49/57 indicated that TR and TS cells were equally sensitive to the former virus, but TR cells were three to five times more sensitive to influenza virus A2/Scotland/49/57 than were TS cells. PMID- 4314551 TI - Induction of simian virus 40 antigen in BSC1 transformed cells. AB - Heating to 45 C induced in virus-free clones of simian virus 40 (SV40) transformed BSC(1) cells the synthesis of SV40 viral antigen, as evidenced by immunofluorescence. Up to 3.8% of the cells exhibited viral antigen 72 hr after heating to 45 C for 30 min. Depletion of arginine from the medium of the heated cells enhanced and increased the percentage of cells synthesizing viral antigen to 11%. Cytosine arabinoside completely inhibited the induction of the viral antigen. No infectious virus was recovered from the cells in which synthesis of viral antigen was induced. However, small amounts of infectious SV40 virus were rescued from the BSC(1) transformed cells by fusion with rabbit kidney cells or by treatment with mitomycin C. PMID- 4314552 TI - Uncoating of poliovirus by isolated plasma membranes. AB - Poliovirus type I LSc strain labeled with (14)C-uridine was adsorbed onto isolated plasma membranes and incubated with them. When membranes from Hep-2 or Vero cells were used, 22% of the label was converted to a trichloroacetic acid soluble form, when trypsin or ribonuclease was added, the fraction rendered soluble was increased, and when the two enzymes were added in sequence, 85% or more of the label became trichloroacetic acid-soluble. This labilization of poliovirus could be reproduced when butanol-solubilized proteins from membranes were substituted for the whole plasma membranes, but it did not occur with membranes from polio-virus-resistant calf kidney or BHK-21 cells. PMID- 4314553 TI - Polyacetal carboxylic acids: a new group of antiviral polyanions. AB - Chlorite-oxidized oxypolysaccharides are polyacetal carboxylic acids. They inhibited the cytopathic effect of vesicular stomatitis virus in mouse embryo cell cultures challenged at low input multiplicity. After intraperitoneal injection of these compounds in mice, interferon appeared in the circulation. The compounds also protected mice against lethal mengovirus infection and against the development of experimental pox lesions on the tail. Chlorite-oxidized oxyamylose was antiviral only when at least 64% of the glucopyranose units were oxidized, an observation which suggested a correlation between charge density and antiviral effect. The antiviral activity was also influenced by the molecular weight, as demonstrated by the fact that chlorite-oxidized dextrans which had a high intrinsic viscosity were more active than those with low intrinsic viscosity. PMID- 4314554 TI - Antiviral activity of chlorite-oxidized oxyamylose, a polyacetal carboxylic acid. AB - Intraperitoneal injection of chlorite-oxidized oxyamylose (COAM) protected mice against mengo, vaccinia, Semliki Forest, and influenza APR8 viruses. Topical administration in the eye of rabbits partially inhibited the development of experimental herpetic keratoconjunctivitis. COAM resembled polyacrylic acid in many aspects, but it was markedly less toxic. For systemic administration, the therapeutic index was on the order of magnitude of 1:300 to 1:500. Although the in vivo antiviral effect of COAM wore off faster than that of polyacrylic acid, protection lasted for several weeks. Against mengovirus, such prolonged protection was achieved only when polymer and virus were injected intraperitoneally. Protection against intravenous vaccinia virus was not dependent on the injection route of COAM. Experiments on the mode of action of COAM pointed to macrophages as possible mediators of the antiviral effect. The fact that small amounts of interferon appeared in the serum after administration of high doses of COAM suggests that interferon may play a role in the induction of antiviral resistance by COAM. PMID- 4314555 TI - Synthesis and cleavage of enterovirus polypeptides in mammalian cells. AB - Evidence is presented that the entire enterovirus ribonucleic acid genome is translated into a single giant polypeptide of well over 200,000 daltons molecular weight. This giant protein was detected repeatedly in coxsackievirus B1-infected cells, even in the absence of amino acid analogues. The enzymes which cleave this giant protein into smaller structural and enzymatic proteins accumulate with increasing time after infection. It appears that they are either virus-coded proteolytic enzymes or else host enzymes which are activated or released from an intracellular site as a result of virus infection. These cleavage enzymes do not cause grossly apparent cleavage of host-cell proteins. PMID- 4314556 TI - Chemical studies on polyoma and Shope papilloma viruses. AB - Polyoma and Shope papilloma viruses were purified and analyzed by chemical and physical methods. Disc electrophoresis of degraded virions indicated the presence, in both cases, of only one major species of polypeptide subunit. The weight of the peptide chain of polyoma virus was estimated in 8 m urea to be about 45,000 avograms, based on the sedimentation rate in a sucrose-urea gradient and the diffusion coefficient estimated from the differential migration in electrophoresis in gels of different pore size. The presence of a minor peptide of smaller size was suggested by carboxyl-terminal and sedimentation analyses. The amino acid composition of polyoma capsid protein was reported. Chemical analyses showed that polyoma virus and Shope papilloma virus contained 16 and 17.5% deoxyribonucleic acid, respectively. Light scattering by the polyoma virion showed it to have a molecular weight of 22 x 10(6) and a diameter of 54 nm. PMID- 4314557 TI - Trypsinized placental cell cultures for the propagation of viruses and as "feeder layers". AB - The preparation and properties of cell cultures derived from human placental tissue are described and their usefulness for the propagation of animal viruses and as "feeder layers" is indicated. PMID- 4314558 TI - [Symposium: welchii and botulinum bacilli]. PMID- 4314560 TI - [Criteria for identification of Clostridium perfringens. 6. Clostridium paraperfingens sp. nov]. PMID- 4314559 TI - [Symposium: study of carcinogenic adenovirus in Japan]. PMID- 4314561 TI - [Recent trend in neurology]. PMID- 4314562 TI - Irradiation of dihydrothymine in frozen sulfuric acid solutions. PMID- 4314563 TI - Intranasal inoculation of feedlot calves with TELC strain parainfluenza-3 vaccine. PMID- 4314564 TI - Effect of angiotensin on myocardial function. PMID- 4314566 TI - Thyroid hormone in heat-acclimated hamsters. PMID- 4314565 TI - Effect of prolonged infusion of angiotensin II on ionic composition of the arterial wall. PMID- 4314567 TI - Contribution of venous resistance to total vascular resistance in skeletal muscle. PMID- 4314568 TI - Effect of ethyl p-chlorophenoxyisobutyrate on rat adipose lipoprotein lipase activity. PMID- 4314569 TI - Angiotensin receptors. PMID- 4314570 TI - Circadian rhythm of mouse liver phosphoenolpyruvate carboxykinase. PMID- 4314571 TI - Effects of prostaglandins on basal and stimulated thyroid function. PMID- 4314572 TI - Litigation following vaccination of dogs. PMID- 4314573 TI - 5-Amino-4-hydroxyvaleric acid: a new intermediate in 5-aminolevulinate metabolism of Rhodospirillum rubrum. PMID- 4314574 TI - Carbamyl phosphate: glucose phosphotransferase activity of hepatic microsomal glucose 6-phosphatase at physiological pH. PMID- 4314575 TI - Oxygen toxicity and carbon deprivation in Astasia longa. PMID- 4314576 TI - On the specificity of cytidine diphosphate diglycerides in monophosphoinositide biosynthesis by rat brain preparations. PMID- 4314577 TI - Carnitine palmitolyltransferase activity and fatty acid oxidation by livers from fetal and neonatal rats. PMID- 4314578 TI - Studies of the binding of adenine to adenine phosphoribosyltransferase. PMID- 4314579 TI - The role of magnesium ion in the adenine phosphoribosyltransferase reaction. PMID- 4314580 TI - [Transmission experiments with the exanthema virus from horses to cattle]. PMID- 4314581 TI - Influence of UV-inactivated HVJ on RSV rescue in cultures of different virogenic mammalian cells mixed with normal sensitive chicken cells. PMID- 4314582 TI - [Some aspects of the error of hospitalization of aged subjects in psychiatric hospitals]. PMID- 4314583 TI - [Observations on therapy with natural conjugated estrogens in pre- and post menopausal subjects]. PMID- 4314584 TI - [Experimental studies on the problem of sensitivity to beryllium]. PMID- 4314585 TI - A scanning, recording and integrating microinterferometer. PMID- 4314586 TI - [Cleavage of various naphthol carboxylic acid esters by esterases in the tanycyte ependyma of the 3d ventricle of Wistar rats]. PMID- 4314587 TI - Discharge planning. PMID- 4314588 TI - Action of cyclic adenosine 3',5'-monophosphate in vitro on the uptake and incorporation of uridine into ribonucleic acid in ovariectomized rat uterus. PMID- 4314589 TI - The relationship of protein synthesis to early transcriptive events in bacteriophage T4-infected Escherichia coli B. PMID- 4314590 TI - Analysis of the amino acid binding to the proline transfer ribonucleic acid synthetase of Escherichia coli. PMID- 4314591 TI - The stimulatory effect of luteinizing hormone on adenyl cyclase in the bovine corpus luteum. PMID- 4314592 TI - Gluconeogenesis in the isolated perfused rat kidney. PMID- 4314593 TI - Enzymes that destroy blood group specificity. I. Purification and properties of alpha-L-fucosidase from Clostridium perfringens. PMID- 4314594 TI - Purification and properties of ribonucleotide reductase from leukemic mouse spleen. PMID- 4314595 TI - Inhibition of gluconeogenesis by butylmalonate in perfused rat liver. PMID- 4314596 TI - Enhancement of the activity of horse liver alcohol dehydrogenase by modification of amino groups at the active sites. PMID- 4314597 TI - The mechanism of action of ethanolamine deaminase. VI. Ethylene glycol, a quasi substrate for ethanolamine deaminase. PMID- 4314598 TI - Properties of purified methylmalonate semialdehyde dehydrogenase of Pseudomonas aeruginosa. PMID- 4314599 TI - Inhibition of the stearyl coenzyme A desaturase system by sterculate. PMID- 4314600 TI - Requirement for reduced diphosphopyridine nucleotide-cytochrome b5 reductase in stearly coenzyme A desaturation. PMID- 4314601 TI - [Results of therapy of Wilms' tumor in children]. PMID- 4314602 TI - [Surgical treatment of carotid body tumors]. PMID- 4314603 TI - [Plasmatic and erythrocytic angiotensinase activity in subjects with chronic uremia before and after treatment with dialysis]. PMID- 4314604 TI - [Human plasmatic and erythrocytic angiotensinase activity in patients with liver diseases]. PMID- 4314605 TI - [Progress and limitation in x-ray diagnosis of stomach cancer]. PMID- 4314607 TI - Inapparent congenital cytomegalovirus infection. Clinical and epidemiologic characteristics in early infancy. PMID- 4314608 TI - [A case of malignant synovioma of the neck]. PMID- 4314606 TI - Antibody responses to the Epstein-Barr virus and cytomegaloviruses after open heart and other surgery. PMID- 4314609 TI - [Laryngeal myoblastoma]. PMID- 4314611 TI - [Biological activities of a new synthetic corticotropin, (Gly']-ACTH(1-18) octadecapeptide amide(50022-S)]. PMID- 4314610 TI - Sleep patterns following 205 hours of sleep deprivation. PMID- 4314612 TI - [Laboratory indentification of viruses of the leukemia-sarcoma group]. PMID- 4314613 TI - [A study of the properties of attenuated cold variant of type O foot-and-mouth disease virus]. PMID- 4314614 TI - [Age-dependence of some cross sectional measurements and length of the human femur]. PMID- 4314615 TI - Bradykinin induced eosinophilia in "skin windows". PMID- 4314616 TI - Bilateral Wilm's tumor: a case report and a survey of nineteen cases in Japanese literature. PMID- 4314617 TI - A histopathologic study on the effect of alcohol on cirrhosis and hepatoma of autopsy cases in Japan. PMID- 4314618 TI - Topical antibiotic prophylaxis in contaminated wounds. Experimental evaluation. PMID- 4314619 TI - Alkylated pyrimidine derivatives as antiviral agents. I. Syntheses and antiviral screening of alkylpyrimidine and 5-alkyluracil nucleoside. PMID- 4314620 TI - Alkylated pyrimidine derivatives as antiviral agents. II. Inhibition of early stages of viral multiplication by 5-alkyluracil and 5-alkyluracil nucleoside. PMID- 4314621 TI - The effects of DBM on rat ascites tumors and antibody production. PMID- 4314622 TI - [Effects of estrogens on vascular permeability stimulation]. PMID- 4314623 TI - [Some observations on plasma cortisol in the obstetrical and gynecological field]. PMID- 4314624 TI - [Further virological research in acute respiratory diseases of childhood]. PMID- 4314625 TI - [Mixed mesodermal tumor of the uterus (Muller's duct tumors)]. PMID- 4314626 TI - A study of ACTH and CRF in chickens. PMID- 4314627 TI - The role of vasotocin and of CRF in ACTH release in the chicken. PMID- 4314628 TI - Lipids in vitamin A deficient chicken cartilage and new bone. PMID- 4314629 TI - Phosphatase activity of listeria (preliminary report). PMID- 4314630 TI - Course of air-borne infection caused by B virus (Herpesvirus simiae). 5. Significance of viraemia and role of blood leucocytes of B-virus, particularly air-borne infection of rabbits. PMID- 4314631 TI - [Supraglottic glomus tumor (glomus laryngicum superior)]. PMID- 4314632 TI - [BNS-convulsions with hypsarrhythmia in tuberous sclerosis of the brain]. PMID- 4314634 TI - [Differential diagnosis of primary brain sarcomas and glioblastomas]. PMID- 4314633 TI - [Problems of allergic reactivity in surgery]. PMID- 4314635 TI - [Clinical experiment with a new pommade combining terramycin and polymyxin B (Primyxin)]. PMID- 4314636 TI - [Cutaneous histiocytoma with giant cell granulomatous foci (microscopic study)]. PMID- 4314639 TI - [Ultrastructural study of neural receptors of the penis in pigs]. PMID- 4314638 TI - [Quick cytochrome oxidase test for the detection of gonococcal urethritis]. PMID- 4314637 TI - [On the possible structural identity of cutaneous mechanoreceptors. Preliminary study with the electron microscope]. PMID- 4314640 TI - [8th International Symposium on the Progress in Internal Medicine, 10-22-1969. Arterial Hypertension. 3. Physiopathology]. PMID- 4314641 TI - Study of pregnancy ketosis in the rat. PMID- 4314642 TI - [Side effects of corticosteroid treatment in large animals]. PMID- 4314643 TI - [Clinical picture of Rhinovirus infection in adus]. PMID- 4314644 TI - [Experiences in the surgical treatment of lung tumors]. PMID- 4314645 TI - [Pulmonary adenomatosis and its intra vitam radiological diagnosis]. PMID- 4314646 TI - Preservation of the cornea for penetrating keratoplasty. An experimental study. PMID- 4314648 TI - [Study of the effect of ACTH preparations]. PMID- 4314649 TI - [Experience in postoperative irrigation with polymyxin B]. PMID- 4314647 TI - [Studies of some viomycinmethyltetracyclines]. PMID- 4314650 TI - [Endocrine edematous exophthalmos and orbital venous circulatory blocking. Value of phlebography]. PMID- 4314651 TI - Vestibular influences during sleep. VI. Vestibular control of autonomic functions during the rapid eye movements of desynchronized sleep. PMID- 4314652 TI - Modulation of sensory projections in anterolateral column of cat spinal cord by peripheral afferents of different size. PMID- 4314654 TI - [Use of hyperbaric oxygen in various neurologic diseases. (Preliminary report)]. PMID- 4314653 TI - [Significance of enzyme histochemistry in the diagnosis of secondary carcinomas of the skin]. PMID- 4314655 TI - [Experience in anti-aphthous vaccination in pigs]. PMID- 4314656 TI - [Preliminary study of an enterovirus isolated from a lesion of bovine balano posthitis]. PMID- 4314657 TI - [Duration of immunity after the use of anti-aphthous vaccine prepared with 10 and 25 milligrams of saponin per dose]. PMID- 4314658 TI - [The tegumentary stimulotherapy. 2. Electric stimulation]. PMID- 4314659 TI - A comparison of sleep patterns in natural and mandrax- and tuinal-induced sleep. AB - A within-subject comparison of the effects on the overnight sleep EEG of 1 tablet of Mandrax (containing methaqualone base 250 mg. and diphenhydramine hydrochloride 25 mg.) and 200 mg. Tuinal (equal parts of quinalbarbitone sodium and amylobarbitone sodium) in 14 normal subjects is reported.Mandrax-induced sleep was not significantly different from natural sleep in the duration of light, moderate, deep and REM phases. Tuinal produced a significant reduction in REM sleep (P < 0.01) compared with natural sleep and with Mandrax-induced sleep. PMID- 4314661 TI - Inhibition of glyceraldehyde-3-phosphate dehydrogenase by glyoxylate. PMID- 4314660 TI - Effect of different levels of pulse protein (Cicer arietinum) on liver enzymes. PMID- 4314662 TI - [A case of poliomyelitic paralysis caused by type 3 poliovirus in an unvaccinated child. Epidemiological considerations on the circulation of poliomyelitis virus in the vaccinal period]. PMID- 4314664 TI - Effects of pyrophosphate and diphosphonate on fluoride uptake by hydroxyapatite. PMID- 4314663 TI - The effects of diphosphonate, pyrophosphate and sodium foride on drinking habits of Osborne-Mendel rats. PMID- 4314666 TI - [Autopsy case of malignant insulin-producing islet cell tumor and review of the literature]. PMID- 4314665 TI - A FEW ENZYMATIC AND A/Nordio S, Cordone G, Gatti R, Marchi AG, Moscatelli P, Vignola P: A few enzymatic and immunologic researches in children with coeliac disease and other chronic enteropathies and with immunologic deficiencies. PMID- 4314667 TI - [Use of conjugated estrogens in ophthalmology]. PMID- 4314668 TI - [An unusual case of fatal poisoning by magnesium fluosilicate]. PMID- 4314669 TI - [Primary epithelial tumors of the renal pelvis. Critical review of 24 cases]. PMID- 4314670 TI - Quantitative enzyme patterns in the nephron of the healthy human kidney. PMID- 4314671 TI - [Pseudomonas pyocyanea infections in otorhinolaryngology]. PMID- 4314672 TI - [Change in the blood level of 17-hydroxycorticosteroids in the formation of focal and destructive forms of pulmonary tuberculosis]. PMID- 4314673 TI - Subacute toxicity of sterigmatocystin to rats. PMID- 4314674 TI - [Dietetics in hereditary enzyme deficiencies]. PMID- 4314675 TI - [Practical applications of diabetic diet in relation to dietary habits in various European countries]. PMID- 4314676 TI - [Primary mesenteric lymphadenitis due to toxoplasmosis]. PMID- 4314677 TI - [Nail changes in idiopathic hemochromatosis]. PMID- 4314678 TI - [Pneumococcal meningitis. 31 cases]. PMID- 4314679 TI - [Standard radiological signs of tropical liver abscess]. PMID- 4314680 TI - [Mediastinal emphysema, a frequent complication of measles in tropical environment. 46 cases]. PMID- 4314681 TI - [Disturbances and dangers of artificial heart stimulation]. PMID- 4314682 TI - [Inhibition of proliferative activity of partially resected liver after administration of diethylnitrosamine]. PMID- 4314683 TI - Epidemiology of primary central nervous system neoplasms. II. Case-control study. PMID- 4314685 TI - Liver enzymes in hypertension. PMID- 4314686 TI - Benign nonchromaffin paraganglioma of the duodenum. Report of a case and review of the literature. PMID- 4314684 TI - Enteroviruses in rural families and their domestic animals. PMID- 4314687 TI - Cushing's syndrome secondary to a benign paraganglioma. PMID- 4314688 TI - Measurement of acetyl coenzyme A in rat liver. PMID- 4314689 TI - Studies on the chain length determination of large oligomers from MS2 RNA. PMID- 4314690 TI - Interference by carbohydrate and other substances in the estimation of protein with the Folin-Ciocalteu reagent. PMID- 4314691 TI - The quantitative and qualitative analysis of alkyl alpha-glycerol ethers as alkoxy acetaldehydes. PMID- 4314692 TI - [Comparative action of human growth hormone and synthetic anabolics on the growth rate in hypothalamo-hypophyseal dwarfism]. PMID- 4314693 TI - [Therapeutic experience in 7 cases of hypophyseal dwarfism treated by human growth hormone]. PMID- 4314694 TI - [On diverse changes of the hypothalamo-hypophyseal complex in white rats treated with ACTH]. PMID- 4314695 TI - [Cancer metastasis in O.R.L]. PMID- 4314696 TI - [Properties of ectromelia virus in cell cultures]. PMID- 4314697 TI - [Serological characteristics of enteroviruses isolated from pig lungs]. PMID- 4314698 TI - [Vigilance and nyctohemeral rhythms in the rat. Induced variations in the irradiated animal]. PMID- 4314699 TI - Vitamin D stimulation of calcium-dependent adenosine triphosphatase in chick intestinal brush borders. PMID- 4314700 TI - Reaction of inorganic phosphate with mitochondrial respiratory chain. PMID- 4314701 TI - Synthesis of estriol 16-alpha-(alpha-D-glucoside) by enzymic transglucosylation. PMID- 4314702 TI - [Recent acquisitions on curarisation]. PMID- 4314703 TI - Synchronization and coupling of phases in periodic processes of conditioning. PMID- 4314704 TI - [Diagnostic difficulties and treatment of mandibular endothelioma in a 7-year-old child]. PMID- 4314705 TI - Interference of ethanol and sorbitol with hepatic ketone body metabolism in normal, hyper- and hypothyroid rats. PMID- 4314706 TI - Acylglucoses of the corynebacteria and mycobacteria. PMID- 4314707 TI - Effect of ethanol metabolism on redox state of steroid sulphates in man. PMID- 4314709 TI - [Structure of the corynomycolic acids of Corynebacterium hofmanii and their biogenetic implication]. PMID- 4314708 TI - Energy production in rat parotid gland. Relation tonzyme secretion and effects of caium. PMID- 4314710 TI - Regulation of liver pyruvate kinase and the phosphoenolpyruvate crossroads. PMID- 4314711 TI - The dissimilation of higher dicarboxylic acids by Pseudomonas fluorscens. PMID- 4314712 TI - Amniographic diagnosis of trophoblastic disease. PMID- 4314713 TI - Isolation of anaerobic bacteria from clinical specimens. PMID- 4314714 TI - Histologic and lipid studies of sural nerves in inherited hypertrophic neuropathy: preliminary report of a lipid abnormality in nerve and liver in Dejerine-Sottas disease. PMID- 4314716 TI - [Eye changes in cytomegaly]. PMID- 4314715 TI - [Clinical and morphological observations on a case of digital glomangioma]. PMID- 4314717 TI - [The Australia antigen and the hepatitis virus]. PMID- 4314719 TI - [Repercussion of corticotherapy on the hypothalamo-pituitary-adrenal axis function]. PMID- 4314720 TI - [Physiology of ACTH secretion]. PMID- 4314718 TI - [Review of antibiotics]. PMID- 4314721 TI - The isolation of herpes virus from human corneal lesions. PMID- 4314722 TI - [Biological assay of progestinics and antiprogestinics]. PMID- 4314723 TI - Effect of glucosamine and benzylidene-glucosamine on 35SO4-incorporation into cartilage and aortic tissues. PMID- 4314724 TI - Angiographic localization of insulinomas: high reported success rate and two additional cases. PMID- 4314725 TI - Sebaceous lymphadenoma of the parotid gland: associated with a case of bilateral parotid gland tumors. PMID- 4314726 TI - Effect of mercurials on NADH oxidation and energy-linked hydrogen ion gradient in submitochondrial particles. PMID- 4314727 TI - Phosphorylation coupled to NADH oxidation with fumarate in Streptococcus faecalis 10Cl. PMID- 4314728 TI - Some aspects of the binding of Cu (II) to human hemoglobin and its subunits. PMID- 4314729 TI - Preparation and properties of a cyclic 3',5'-nucleotide phosphodiesterase isolated from frog erythrocytes. PMID- 4314731 TI - A neuromuscular syndrome of scapuloperoneal distribution. PMID- 4314730 TI - A theoretical examination of ionic interactions between neural and non-neural membranes. AB - Evidence from electron microscopy indicates that the separation between adjacent membranes of the central nervous system (CNS) is less than 500 A and perhaps as small as 100-250 A. The rapid K(+) efflux associated with the neural action potential may therefore be sufficient to affect the local extracellular potassium concentration and, via their partial dependence upon the potassium equilibrium potential, alter the electrical states of nearby neural and glial membranes. This new concept of a transient and local depolarizing "ionic interaction" between active and inactive membranes of the CNS is here examined theoretically and its magnitude calculated as a function of (a) the intermembrane separation, (b) the membranes' electrochemical characteristics, and (c) the rate at which K(+) can diffuse away from the vicinity of the active (neural) membrane. My results indicate that the interaction is in the millivolt range and therefore significant in the modulation of postsynaptic and presynaptic information processing; in particular configurations the postulated interaction alone may be suprathreshold. Membrane noise and local synchrony in groups of neurons may reflect these local, K(+)-mediated interactions. The transient ionic interaction between active neural and nearby glial membrane is also in the millivolt range; however, the relevance of neuroglia to neuronal function is obscure. Certain pathological states, such as seizure and spreading depression, have an obvious phenomenological correspondence to the results presented here and are briefly discussed. PMID- 4314732 TI - Hereditary hypertrophic neuropathy. Report of two cases of an autosomal recessive variant. PMID- 4314733 TI - [Pharmacological study of asymmetrical O,O,O,O-tetraethyldithiopyrophosphate, a recently synthesized organophosphoric compound]. PMID- 4314734 TI - Responses of neurons in the dorsal nucleus of the lateral lemniscus of cat to binaural tonal stimulation. PMID- 4314736 TI - Rat liver plasma membranes in essential fatty acid deficiency. PMID- 4314735 TI - Corticofugal influence on activity of lateral geniculate neurons in the cat. PMID- 4314737 TI - Management of the narcotic-addicted surgical patient: concepts of medical and surgical care. PMID- 4314738 TI - Wound healing: biochemical events and potential role of collagenase. PMID- 4314740 TI - Bronchial adenoma. PMID- 4314739 TI - Observations on ultrastructural morphology of bronchogenic carcinoma. PMID- 4314741 TI - [Clinical and pathological study of 6 fatal cases of asthma]. PMID- 4314742 TI - [Carcinomatosis of the meninges in a case of primary mucogenous cancer of the ovary]. PMID- 4314743 TI - [Cyclic-AMP]. PMID- 4314745 TI - [Use of delayed-action beta 1-24 corticotropin in the therapy of rheumatoid arthritis]. PMID- 4314744 TI - [Alcohol and carbohydrate metabolism. I]. PMID- 4314746 TI - Emulsified ethiodol as a bronchographic contrast agent. Preliminary observations. PMID- 4314747 TI - Skeletal manifestations of congenital cytomegalic inclusion disease. PMID- 4314748 TI - Early appearance of the secondary vertebral ossification centers. PMID- 4314749 TI - Further studies in lymphokinetic considerations of lymphography and intralymphatic therapy. PMID- 4314750 TI - [Articular chondrocalcinosis and chronic evolutive polyarthritis (3 cases)]. PMID- 4314752 TI - [Colloid in the parathyroid glands]. PMID- 4314751 TI - The electron microscopic demonstration of acetylcholinesterase activity in some cholinergic and non-cholinergic synapses of the rat brain. PMID- 4314753 TI - [Occurrence of cytochrome oxidase, lactate dehydrogenase and glucose-6-phosphate dehydrogenase in the heart wall of the hen (Gallus domesticus L.)]. PMID- 4314754 TI - Renal function, renin activity and endogenous vasoactive substances in cirrhosis. PMID- 4314755 TI - Rapid spectrophotometric method for determination of micro amounts of copper in proteins. PMID- 4314756 TI - Micro method for the quantitative determination of delta 22-sterols. PMID- 4314757 TI - Scintillation counting of 32P without added scintillator in aqueous solutions and organic solvents and on dry chromatographic media. PMID- 4314758 TI - Method of determining oxygen concentrations in biological media, suitable for calibration of the oxygen electrode. PMID- 4314759 TI - Automated multiple enzyme analysis systems. PMID- 4314760 TI - [Equine coital exanthema]. PMID- 4314761 TI - [Fluoresence-serological diagnosis of rhinopneumonitis virus infections. (Preliminary report)]. PMID- 4314762 TI - Effects of adenosine 3',5'-cyclic monophosphoric acid on certain light-induced reactions and on ATPase activity of isolated chromatophores from Rhodospirillum rubrum. PMID- 4314763 TI - Mossbauer spectroscopy of lyophilized rat liver microsomes. PMID- 4314764 TI - Exchange of adenine nucleotides in digitonin-treated mitochondria. PMID- 4314765 TI - The state of copper in stellacyanin and laccase from the lacquer tree Rhus vernicifera. PMID- 4314766 TI - Non-heme iron (iron-sulfur) proteins of Azotobacter vinelandii. PMID- 4314767 TI - Iron metabolism and absorption studies in the X-linked anaemia of mice. PMID- 4314768 TI - Studies on the interaction between serum bactericidal activity and antibiotics in vitro. PMID- 4314770 TI - The effect of adrenocorticotropic hormone and cortisone on the mucous cells of the rat stomach. I. Determination of hexosamines in the fundus and pyloric mucous membrane. PMID- 4314769 TI - [Enzyme-histochemical behavior of Leydig cells in rat testes following estrogen treatment in relation to a spontaneous restitution effect]. PMID- 4314771 TI - The effect of corticotrophine and cortisone on the content of fucose in stomach mucosa of white rats. PMID- 4314772 TI - Studies on succinate oxidation. I. The use of intact tissue sections. PMID- 4314773 TI - Proteins released from chick embryo fibroblasts in culture. II. Studies on cells in different states of culture. PMID- 4314774 TI - Effects of various photoperiods on the temporal distribution of paradoxical sleep in rats. PMID- 4314775 TI - Effect of procaine on asphyxial rigidity. PMID- 4314776 TI - Stereospecificity of the prostaglandin 15-dehydrogenase from swine lung. PMID- 4314777 TI - Microbiological assay of cyclic 3',5'-AMP. PMID- 4314778 TI - [Rate of degeneration of preimplanted rat ova]. PMID- 4314779 TI - [Degeneration rates of preimplanted ova of rats with hypervitaminosis A and vitamin A deficiency]. PMID- 4314780 TI - Isolation of an antibiotic-resistant, lactose-fermenting strain of Proteus rettgeri. PMID- 4314781 TI - [Mycoplasma in human pathology]. PMID- 4314782 TI - Increase in antiviral activity of polynucleotides by thermal activation. PMID- 4314783 TI - [Should the corticotropic activity unit be abandoned?]. PMID- 4314784 TI - [Status of the therapy of multiple sclerosis]. PMID- 4314785 TI - Primate electrophysiology, particularly related to sleep. ARL-TR-69-5. PMID- 4314786 TI - [Stimulation of immunity to isologous transplantable hepatoma 22a and 46 using Freund's adjuvant in C3HA mice]. PMID- 4314787 TI - [The oncogenic effect of urethane and myeloid chlorleukemia virus on adult mice]. PMID- 4314788 TI - [Features of the pathology and treatment of malignant tumors of the carotid body]. PMID- 4314789 TI - [Fluorescent serological studies on the multiplication of adenoviruses of cattle and pigs in tissue cultures]. PMID- 4314790 TI - The first isolation of Myxovirus influenzae A2-equi in Yugoslavia. PMID- 4314791 TI - [The effect of angiotensin II on cerebral circulation]. PMID- 4314792 TI - [Active external hydrocephalus of the posterior fossa]. PMID- 4314793 TI - [Initial trials using very high voltages in neuroradiology]. PMID- 4314794 TI - [Orbital phlebography in the study of tumors of the base of the skull]. PMID- 4314795 TI - "Meningioma blush" in pituitary adenoma. PMID- 4314796 TI - [Peroperative selective angiography in hemispheric cerebral tumors]. PMID- 4314797 TI - Accuracy of brain scanning. Comparison with other procedures for brain tumor detection. PMID- 4314798 TI - [Ethyl mono-iodo-stearate and myelography]. PMID- 4314799 TI - [Clinical experience with the SH 617 (L) suspension in myelography]. PMID- 4314800 TI - Acinar-islet cells in the exocri pancreas of the adult cat. PMID- 4314802 TI - Acute reversal of the sleep-waking cycle in man. Effect on sleep stage patterns. PMID- 4314801 TI - [Multiple congenital malformations in a Congolese child apparently due to trisomy 13-15]. PMID- 4314803 TI - Transient neonatal myasthenia. Clinical and electromyographic studies. PMID- 4314804 TI - Steroidogenesis by the rabbit adrenal gland in vitro. PMID- 4314805 TI - The antigenic component common to all Clostridium perfringens type A strains. PMID- 4314806 TI - [Behavior of plasma phospholipids in normal children. (Thin layer chromatographic analysis)]. PMID- 4314807 TI - [A study of diaminoxidase in the pig's kidney by electron paramagnetic resonance]. PMID- 4314809 TI - The nature of inhibition of mitochondrial malate dehydrogenase by thyroxine, iodine cyanide and molecular iodine. PMID- 4314808 TI - The NAD kinases of Saccharomyces cerevisiae. PMID- 4314811 TI - [Symposium: action mechanism of hormones. 2. Action mechanism of ACTH with special emphasis on the significance of adrenergic agents]. PMID- 4314810 TI - The phosphodiesterases in the rat pancreas. PMID- 4314812 TI - [Symposium: action mechanism of hormones. 5. Hormonal regulation of sugar transport]. PMID- 4314813 TI - [Symposium: action mechanism of hormones. 6. Action mechanism of LH- investigation of c-AMP in vivo]. PMID- 4314814 TI - [Symposium: interrelations among hormones. 1. Pituitary gland; ACTH and MSH]. PMID- 4314815 TI - [On the immunitary condition among children in Savona and the diffusion of poliovirus in the 3 years following mass antipoliomyelitic vaccination]. PMID- 4314816 TI - Preliminary report on the effects of foot and mouth vaccination on semen quality of cross bred bulls. I. PMID- 4314817 TI - Allergy and infection. IX. The significance of susceptibility factors. PMID- 4314818 TI - Hereditary ulnar and fibular dimelia with peculiar facies. A case report. PMID- 4314819 TI - Relationship between sympathetic ganglion activity and audiogenic seizures in mice. PMID- 4314820 TI - Control by prostaglandin E2 of sympathetic neurotrans-mission in the spleen. PMID- 4314821 TI - Long chain fatty alcohols in normal and neoplastic tissues. PMID- 4314822 TI - Three dimensional reconstructions of spherical viruses by fourier synthesis from electron micrographs. PMID- 4314823 TI - Cooperative study in the evaluation of therapy in multiple sclerosis. ACTH vs. placebo--final report. PMID- 4314824 TI - Gold neuropathy. PMID- 4314825 TI - The relationship of nocturnal headaches to sleep stage patterns. PMID- 4314826 TI - [Difficulties in the diagnosis of congenital hyperplasia of adrenal glands]. PMID- 4314828 TI - [Histopathological and developmental study of chronic occupational radiodermatitis of the fingers]. PMID- 4314827 TI - [Masculinizing tumors of the adrenal gland. A case]. PMID- 4314829 TI - [4 cases of calcifying pancreatitis in hemochromatosis]. PMID- 4314830 TI - [Electrical activity of the heart]. PMID- 4314831 TI - [Moschcowitz's syndrome and severe digestive hemorrhage]. PMID- 4314832 TI - [Contribution of thermography to the diagnosis of cerebrovascular diseases]. PMID- 4314833 TI - [Mediastinal hematopoietic tumors. Value of complementary studies, especially isotopic ones]. PMID- 4314835 TI - [Clinicomorphological characteristics and certain problems of the pathogenesis of involvement of the lungs in influenza and adenovirus infections in children]. PMID- 4314834 TI - [Bone tuberculosis in migrants. 6 cases]. PMID- 4314836 TI - [Standardization of polyoma virus-induced rat tumors]. PMID- 4314837 TI - [Cancers in rats and mice fed with commercial fish feeds]. PMID- 4314838 TI - [Drug sensitivity of the so-called atypical mycobacteria]. PMID- 4314839 TI - Comparison of media for direct isolation and transport of Shigellae from Fecal specimens. AB - Xylose-lysine-deoxycholate (XLD) agar, SS agar, and MacConkey agar for isolating shigellae from fecal specimens were compared. XLD agar was superior to both SS agar and MacConkey agar for isolating Shigella sonnei, and both XLD and SS agar were superior to MacConkey agar for isolating S. flexneri. Direct plating of the fecal specimens in the field resulted in a greater yield of shigellae as compared to transporting specimens to the laboratory either in holding media or enrichment broth. Buffered glycerol saline was superior to other transport media evaluated, yielding 83% of shigella isolates when plated within 48 hr as compared to direct plating. The combination of XLD agar and SS agar is recommended for direct isolation of shigellae, and, whenever possible, these solid media should be taken to the bedside and inoculated directly. PMID- 4314840 TI - Unusual Sphaerophorus species from the large intestine of man. AB - An obligately anaerobic, gram-negative microorganism identified as a Sphaerophorus species was recovered from the fecal material of two cancer (chronic myelogenous leukemia and idiopathic thrombocythemia) patients receiving cobalt radiation therapy. The organism, isolated on sheep blood-agar, exhibited extreme pleomorphism (rods, filaments, and spheroids) and was a major component of the anaerobic fecal microflora. In one patient the numbers of Sphaerophorus species (designated as isolate 6-13-68), Bacteroides species, and Clostridium perfringens declined after irradiation; however, they were stable in this same patient after a second therapeutic dose of radiation. The numbers of anaerobes in the other patient remained fairly consistent after radiation. The biochemical and morphological characteristics and carbohydrate fermentation reactions of isolate 6-13-68 most closely resembled those of Sphaerophorus ridiculosis. PMID- 4314841 TI - Dehydrogenase patterns in the study of Bacteroidaceae. AB - Enzyme patterns were obtained by starch-gel electrophoresis of cell-free extracts from organisms in the family Bacteroidaceae. Esterases, phosphatases, and lactic and succinic dehydrogenases were detected but offered no possibility for classification purposes. Alpha-glycerophosphate dehydrogenase and 6 phosphogluconate dehydrogenase were not detected. Zymograms of malic, glutamic, and glucose-6-phosphate dehydrogenases separated Bacteroides species from Sphaerophorus and Fusobacterium species. Malic dehydrogenase and glucose-6 phosphate dehydrogenase were found in Bacteroides but not Sphaerophorus and Fusobacterium. These dehydrogenase zymograms placed three gram-negative, nonsporeforming anaerobic rod isolates with the Bacteroides species. A close correlation was found between the classification of Bacteroidaceae by zymogram analysis and a numerical taxonomy scheme previously published from this laboratory. PMID- 4314842 TI - Use of glutamic acid to supplement fluid medium for cultivation of Bordetella pertussis. AB - The amino acid consumption by Bordetella pertussis growing in broth containing casein hydrolysate was examined. Serine, proline, alanine, glycine, aspartate, and glutamate were rapidly consumed, in a manner which suggested that they supplied the energy requirements of the organism; exhaustion of the energy source appeared to be the main factor limiting the yield of cells. There was no correlation between the utilization of individual amino acids and the phase of growth; uptake appeared to depend only upon relative concentrations. Consumption of threonine, phenylalanine, histidine, leucine, and methionine was slight; consumption of valine and lysine was variable, and isoleucine was excreted. The addition of monosodium l-glutamate (3 mg/ml) to the broth in shaken flasks increased the cell yield by an average of 43.5%. It had no detectable adverse effect upon the agglutin-producing capacity, agglutinability in antisera versus smooth and rough growth phases, mouse-lethal toxicity, histamine-sensitizing factor potency, or intracerebral protective potency of the culture. Broth supplemented with monosodium l-glutamate has been used over a 2-year period to prepare experimental vaccines by both batch and continuous cultivation methods at controlled pH; the cell yields obtained from the supplemented broth have been up to 52% higher than those from the basal broth. The use of glutamate to replace a proportion of casein hydrolysate in the broth caused a reduction in the cell yield, an alteration in cell morphology, and reduction in the mouse-lethal toxicity, the histamine-sensitizing factor potency, and the intracerebral protective potency of the cells. PMID- 4314843 TI - Evaluation of a new incubation-type indole strip test. AB - A total of 189 of Enterobacteriaceae and three strains of Clostridium perfringens were tested with a new incubation-type indole paper strip. This 4-hr incubation test gave the same results as a standard 48-hr indole test, except with some strains of Proteus rettgeri. Results with P. rettgeri varied somewhat according to the medium upon which the organisms had been grown. PMID- 4314844 TI - Endocrine dysfunction with lung carcinoma. PMID- 4314845 TI - Aldolases as liver function tests. Fructose-1-phosphatase and fructose-1,6 diphosphatase. PMID- 4314846 TI - [Mathematical analysis of the spatial distribution of cytochrome oxidase activity in excited and inhibited nerve cell]. PMID- 4314847 TI - Effects of antidepressant drugs of the imipramine type on central 5 hydroxytryptamine neurotransmission. PMID- 4314848 TI - Platelet lipids. IV. 14C labeled acetate incorporation by isolated platelets. PMID- 4314849 TI - Effect of drugs on hepatic drug metabolism in the fetus and newborn. PMID- 4314850 TI - Radicals formed by the reaction of electrons with amino acids in an alkaline glass. PMID- 4314851 TI - [Plethysmography in diabetic arteriopathies]. PMID- 4314852 TI - [Tubal pregnancy with molar degeneration of the ovum]. PMID- 4314853 TI - Effect of dopamine on the biological activity and in vitro release of ACTH and FSH. PMID- 4314855 TI - Rhinovirus inhibition by 3-substituted triazinoindoles. PMID- 4314854 TI - Effect of an oral contraceptive agent on blood pressure response to renin. PMID- 4314856 TI - Growth of parainfluenza virus in perfused human embryonic lung. PMID- 4314857 TI - Cyclic AMP mediation of bradykinin-induced stimulation of mitotic activity and DNA synthesis in thymocytes. PMID- 4314858 TI - Potentiation of the crop-sac stimulating action of prolactin by ATP. PMID- 4314859 TI - Diethylaminoethyl-dextran enhancement of interferon induction by a complexed polyribonucleotide. PMID- 4314860 TI - Potentiation by alpha-methyldopa of pressor responses to angiotensin. PMID- 4314861 TI - Effect of cyclic 3',5'-adenosine monophosphate and theophylline on lymphocyte transformation. PMID- 4314862 TI - Effects of angiotensin on canine renal blood flow. PMID- 4314863 TI - [Form and position changes of the posterior part of the 3rd ventricle and upper part of the aqueduct in pantopaque ventriculography]. PMID- 4314864 TI - [Clinical and radiological diagnosis of hyperinsulinism]. PMID- 4314865 TI - [Acute intestinal amebiasis in infants]. PMID- 4314866 TI - Effect of agar, calf embryo extract, and polyanions on production of foci of transformed cells by Rous sarcoma virus. PMID- 4314867 TI - The formation of variants with a reversion of properties of transformed cells. IV. Loss of detectable polyoma transplantation antigen. PMID- 4314868 TI - Histone synthesis in polyoma- and SV40-infected cells. PMID- 4314869 TI - Wound tumor virus: purification and fractionation of the double-stranded ribonucleic acid. PMID- 4314870 TI - Influence of inhibitors of protein synthesis on interferon formation in mice. II. Comparison of effects of glutarimide antibiotics and tenuazonic acid. PMID- 4314871 TI - Antigens specified by herpesviruses. I. Effect of arginine deprivation on antigen synthesis. PMID- 4314872 TI - Observations on the envelope properties of RSV(O). PMID- 4314873 TI - [The effect of ACTH on the secretion of gastromucoproteins and other components of gastric juice]. PMID- 4314874 TI - Prednacinolone, a new anti-inflammatory steroid. 2. Biochemical and pharmacological properties. PMID- 4314876 TI - A modern approach to the management of childhood asthma. PMID- 4314875 TI - Studies on antiprotozoans. II. Synthesis and biological activity of some N alkylamino-nitroimidazoles. PMID- 4314877 TI - District nursing sister attached to hospital surgical department. AB - An experiment of attaching a district nursing sister to the surgical department of a general hospital was designed to show the use of the district nursing service for the after-care of patients discharged from hospital after surgical treatment. In a 15-week period about 590 bed days were saved, and only six out of 126 patients discharged early had to be readmitted. Most of the patients and the general practitioners who replied to questionaries about the scheme were in favour of it. PMID- 4314878 TI - Foot-and-mouth disease: a definition of the problem and views on its solution. PMID- 4314879 TI - Malate dehydrogenase of ox kidney. Comparison of the reactivity of sulfhydryl groups and their relationship to activities of the mitochondrial and cytoplasmic enzymes. PMID- 4314880 TI - [Amino-acylation of Escherichia coli tRNA-1-Val by phenylalanine-tRNA synthetase of yeast]. PMID- 4314881 TI - Pathways of hydrogen in mitochondria of Saccharomyces carlsbergensis. PMID- 4314882 TI - Regulation of nitrate reductase activity in Neurospora crassa. PMID- 4314883 TI - Influence of detergents on enzymic activity of cactus mitochondria. PMID- 4314884 TI - Retinal function in an isolated, perfused mammalian eye. PMID- 4314886 TI - Modulation in nucleoside diphosphatase activity of mammotrophic cells of the rat adenohypophysis during secretion. PMID- 4314885 TI - Serologic evidence of an etiologic role for bluetongue virus in hydranencephaly of calves. PMID- 4314888 TI - Extranasopharyngeal juvenile angiofibroma--a case report. PMID- 4314887 TI - A quantitative histochemical study of intestinal mucosa after x-irradiation. PMID- 4314889 TI - Antibodies against commonly isolated enteroviruses in sera from cases of epidemic encehalitis and contacts (Lucknow). PMID- 4314890 TI - Catecholamines and dibenzyline in trauma and adaptation to trauma. PMID- 4314891 TI - Chemodectomas of the vagal body. PMID- 4314893 TI - Fringe medicine. PMID- 4314894 TI - [Antineoplastic drugs in the therapy of malignant tumors in children. Evaluation of cases of the Pediatric Clinic of Genoa]. PMID- 4314892 TI - Effect of tetrodotoxin on electrically-induced release of autonomic mediators in the rabbit sinoatrial node. PMID- 4314895 TI - Peripheral nerve and root lesions developing as a result of haematoma formation during anticoagulant treatment. PMID- 4314896 TI - Peripheral sensorimotor neuropathy in association with a seminoma of an undescended testicle. PMID- 4314897 TI - Induction of cytochromes in human cells by oxygen. AB - The mechanism of cytochrome induction in human cells was investigated. Cultured fibroblasts grown in low oxygen had markedly reduced contents of cytochromes A + A(3), B, and C + C(1) as measured by absorption spectra. Chloramphenicol but not cycloheximide or actinomycin blocked the initial increase in cytochrome oxidase activity in cells shifted from low to ambient oxygen, suggesting that initiation of enzyme induction requires mitochondrial but not cytoplasmic protein synthesis or transcription of nuclear genes. Turnover of cytochrome oxidase was demonstrated in cells in stationary phase. PMID- 4314898 TI - Stimulated formation of adenosine 3',5'-cyclic phosphate in cerebral cortex: synergism between electrical activity and biogenic amines. AB - When cortical slices are incubated with adenine-(14)C, adenine nucleotides are labeled in a small and relatively stable pool. The ATP-(14)C of this pool is readily converted to cAMP-(14)C during incubations with depolarizing agents, such as K(+), ouabain, veratridine, or batrachotoxin. During incubations with these agents, release of acetylcholine and of adenosine into the medium is enhanced. The increase in release of adenosine parallels the enhanced formation of cAMP (14)C elicited by depolarizing agents, providing further evidence that adenosine may serve to couple electrical activity in the central nervous system with formation of cAMP. When adenosine or a depolarizing agent are incubated, together with a biogenic amine, such as histamine, serotonin, or norepinephrine, the combined effect on cAMP-(14)C formation in cortical slices is much more than additive. Extracellular levels of biogenic amines could in this manner modulate cAMP formation and biochemical responses in nervous tissue during electrical activity. PMID- 4314899 TI - Translation-level control of amylase and protein synthesis by epinephrine. AB - The synthesis of RNA, protein, and amylase has been studied in normal and epinephrine-treated slices of rat parotid gland. Epinephrine stimulates synthesis of total cell protein and specifically of amylase, but amylase synthesis is preferentially increased. There is no change in either the specific radioactivity or pattern of labeling of total RNA. In the presence of actinomycin D, epinephrine stimulates secretion of amylase, as well as protein and amylase synthesis. RNA synthesis under these conditions is reduced to 10 per cent of control values. Slices obtained from animals treated with actinomycin D nine and a half hours prior to study show responses to epinephrine comparable to those from control animals, with RNA synthesis inhibited by 70 per cent. Since amylase synthesis is stimulated by epinephrine in the absence of RNA synthesis, control of the production of this enzyme is probably exerted at the level of translation.