PMID- 4194533 TI - Contamination of blood stored in plastic packs. PMID- 4194534 TI - Virus-like particles in serum of an apparently healthy Au-SH-antigen-positive blood-donor. PMID- 4194535 TI - Smoking habits and laboratory tests. PMID- 4194536 TI - Ampicillin rashes. PMID- 4194537 TI - Acetazolamide and renal stone formation. PMID- 4194538 TI - Urinary oestrogen profiles and aetiology of breast cancer. PMID- 4194539 TI - Triethylene tetramine. PMID- 4194540 TI - Effect of L-dopa on seborrhoea of parkinsonism. PMID- 4194541 TI - Amantadine versus L-2 dopa and amatadine plus L-dopa. PMID- 4194542 TI - Herpes encephalitis treated with idoxuridine. PMID- 4194543 TI - Rattlesnike bite. PMID- 4194544 TI - Alan Henderson Hunt, D.M.,M.Ch. Oxon. F.R.C.S. PMID- 4194545 TI - Characterization of cell types in the parenchyma of Schistosoma mansoni. PMID- 4194547 TI - Treatment of acute myocardial infarction. 2. Ventricular ectopic arrhythmias. PMID- 4194548 TI - Structure and evolution of immunoglobulins. PMID- 4194549 TI - [Health legislation]. PMID- 4194550 TI - Purification and electron microscopy of sowthistle yellow vein virus. PMID- 4194551 TI - Acylation and deacylation reactions catalyzed by kynurenine formamidase. PMID- 4194552 TI - Immunochemical quantitation of acute phase reactive proteins in myocardial infarction. PMID- 4194553 TI - Inflammatory bowel disease in a family. Observations related to pathogenesis. PMID- 4194554 TI - Electron microscope observations on the chemical component of the sheath of the middle piece of atypical spermatozoa of the pond snail, Cipangopaludina malleata Reeve. PMID- 4194555 TI - Electron microscope autoradiography with special reference to the problem of resolution. PMID- 4194556 TI - The correlative light and electron microscopy of the islets of Langerhans in some lower vertebrates. PMID- 4194557 TI - Electron microscope studies on the release of histamine from rat peritoneal mast cells. PMID- 4194558 TI - Examination of histochemical techniques for demonstrating histamine in mast cells. PMID- 4194559 TI - [Abnormally high tissue levels of brown pigment under amiodarone administration]. PMID- 4194560 TI - Transurethral resection. PMID- 4194561 TI - [Syntheses of aniso-actinocinyl peptides and aniso-actinomycines utilizing deuterium-labelled intermediates]. PMID- 4194562 TI - Less common types of arthritis. PMID- 4194564 TI - [Detection of polycyclic hydrocarbons in the lipid phase of animal cells by electrochemiluminescence]. PMID- 4194563 TI - [Comparative evaluation of the effect of actinomycin 2703 and of orotic acid on the dimensions of spinal motor neurons subjected to motor load]. PMID- 4194565 TI - Cell types in the pituitary of the medaka, Oryzias latipes. PMID- 4194566 TI - Biochemical differentiation of equine anemias. PMID- 4194567 TI - Excretory micturition cystourethrography (EMCU) in the adult age group. PMID- 4194568 TI - The stability of deviant behavior over time: a reassessment. PMID- 4194569 TI - [Experimental studies on antineoplastic activity of daunomycin. II. Effect of ascite tumor cells in vivo]. PMID- 4194570 TI - [Excretion of radioactive iodine (131I) in the gastric juice, bile and pancreatic juice of chickens]. PMID- 4194571 TI - [Clinical experimentation with chlormadinone acetate in gynecology and obstetrics]. PMID- 4194572 TI - Decline of tissue noradrenaline under the influence of a mitotic inhibitor. PMID- 4194573 TI - Cerebral venous and sinus thrombosis. PMID- 4194574 TI - A long follow-up study of 128 cases of intramedullary spinal cord tumours. PMID- 4194575 TI - Intracranial abnormalities of the external carotid system. PMID- 4194576 TI - Method for preparing Neisseria gonorrhoeae fluorescent antibody conjugate. PMID- 4194577 TI - [Gastrin]. PMID- 4194578 TI - [Cancerogenic hydrocarbons in exhaust gases of automobile engines and their possible elimination]. PMID- 4194579 TI - [Regio olfactoria and nervus olfactorius in the gull, Larus argenatatus]. PMID- 4194580 TI - [Development of the keratohyalin granules in the esophageal epithelium]. PMID- 4194581 TI - Time course of anaphylactic histamine release and morphological changes in rat peritoneal mast cells. PMID- 4194582 TI - Interactions between inhibitors of the axonal amine pump and bretylium in the degeneration release of sympathetic transmitter. PMID- 4194583 TI - The release of histamine, heparin and granule protein from rat mast cells treated with compound 48-80 in vitro. PMID- 4194584 TI - Globule leukocyte and mast cell in bile ducts of cattle naturally infected with liver flukes. PMID- 4194585 TI - [Development of levels of residue in products of animal origin after treatment of cattle mange by lindane]. PMID- 4194586 TI - [The development of the photosynthetic apparatus in dark cultures of Rhodopseudomonas capsulata]. PMID- 4194587 TI - The isolation and characterisation of gas-cylinder membranes and alpha-granules from Anabaena flos-aquae D 124. PMID- 4194588 TI - [Relationship between submicroscopic chloroplast structure and type of carbon nutrition of Chlamydobotrys stellata]. PMID- 4194590 TI - [Immunologic tolerance in guinea pigs to contact dermatitis caused by 2,4 dinitrochlorbenzol and dinitrophenol-protein compounds]. PMID- 4194589 TI - [The bacteriochlorophyll content and protein composition of thylakoids of Rhodospirillum rubrum during morphogenesis of the photosynthetic apparatus]. PMID- 4194591 TI - The effect of colchicine on the transport of axonal protein in the chicken. AB - 1. Small doses (1-10mug) of colchicine injected into the ventral horn of the spinal cord of the chicken caused paralysis in the legs. 2. Colchicine had no effect on the incorporation of leucine into proteins of the spinal cord but markedly decreased the total amount of protein flowing into the axons of the sciatic nerve. 3. This axonal flow of protein proceeded at two rates: a high rate (300mm/day) and a low rate (2mm/day). Although both groups of proteins were affected, the slow transport of protein was more profoundly blocked by colchicine. 4. The results suggest that axonal flow is dependent on the neurotubular system in the axon. PMID- 4194592 TI - Proinsulin in B cells of bovine islets demonstrated by fluorescein or peroxidase labeled specific antibody. PMID- 4194593 TI - Somatosensory evoked potentials of the normal human neonate in REM sleep, in slow wave sleep and in waking. PMID- 4194594 TI - Phase coherence of the alpha rhythm during photic blocking. PMID- 4194595 TI - Changes in the form of the cerebral evoked response related to the speed of simple reaction time. PMID- 4194596 TI - The interaction of visual attention and temporal cortex stimulation on electrical activity evoked in the striate cortex. PMID- 4194597 TI - Primary afferent depolarization in the cuneate nucleus induced by stimulation of cerebellar and thalamic non-specific nuclei. PMID- 4194598 TI - Modifications of dorsal root potentials during cortical seizures. PMID- 4194599 TI - The effect of altered drive states on the contingent negative variation (CNV) in rhesus monkeys. PMID- 4194600 TI - Sleep in the opossum Didelphis marsupialis. PMID- 4194601 TI - Mononeuron excitability in man: a novel method of evaluation by modulation of tonic muscle activity. PMID- 4194602 TI - Hippocampal theta activity and response inhibition. PMID- 4194603 TI - The contingent negative variation and the late positive wave of the average evoked potential. PMID- 4194604 TI - A cryoprobe and cryoplate for reversible functional blockade in the brains of chronic animal preparations. PMID- 4194605 TI - Changes in neuronal activity in hypoxia and asphyxia. PMID- 4194606 TI - The influence of hypoxia on synapses of the spinal cord. PMID- 4194607 TI - The relation between EEG, cerebral metabolism and cerebral circulation as well as their disorders caused by anoxia. PMID- 4194608 TI - Current sources of the EEG. PMID- 4194609 TI - Connections between EEG activity and post-synaptic potentials of spinal motoneurones during convulsions. PMID- 4194610 TI - Connections between pH and d.c. potentials of the brain. PMID- 4194611 TI - Animal experiments on the problem of proprioceptive control of eye movements. PMID- 4194612 TI - The learning behavior of rats following experimental carotid occlusion. PMID- 4194613 TI - Electroencephalography and organ transplantation. PMID- 4194614 TI - EEG and "brain death" following anoxia and ischemia. PMID- 4194615 TI - Clinical and EEG findings in "brain death" following severe brain injuries. PMID- 4194616 TI - EEG follow-ups in severe neurological states after hypoglycemia. PMID- 4194617 TI - The flat EEG and angiography in cerebral death. PMID- 4194618 TI - On the numerical relation between reanimation patients, patients with dissociated brain death and potential organ donors in a reanimation centre. PMID- 4194620 TI - EEG course in phenylketonuria. PMID- 4194619 TI - Metabolic illnesses in children, especially dislipidosis. PMID- 4194621 TI - Patterns of synchronization observed in the rabbit's cortex during gradually increasing loss of nerve cells. PMID- 4194622 TI - Thyroid hormone and brain development. An analysis of polygraphic data of hypothyroid babies before and during treatment. PMID- 4194623 TI - The EEG in pyridoxine-dependent convulsions. PMID- 4194624 TI - The EEG in uraemia. PMID- 4194625 TI - Dialysis disequilibrium syndrome. PMID- 4194626 TI - EEG investigations in different methods of dialysis. PMID- 4194627 TI - The EEG in liver disease. PMID- 4194628 TI - Pre- and post-operative EEG records in patients with Cushing's syndrome. PMID- 4194629 TI - EEG findings in acute porphyria. PMID- 4194630 TI - EEG changes in acute poisoning with organic tin compounds. PMID- 4194631 TI - Reactions and interactions of cortically effective stimuli. PMID- 4194632 TI - Further results of stimulation experiments in kittens. PMID- 4194633 TI - Alterations of the cortical oxygen pressure in generalized seizures. PMID- 4194634 TI - Psychological findings in cases with 4-5 c-sec rhythm. PMID- 4194635 TI - Side to side comparison of acoustic evoked potentials in patients with unilateral intracerebral processes, especially with aphasia. PMID- 4194636 TI - Human cortical evoked potentials in dichoptic stimulation. PMID- 4194638 TI - Artefacts in the "silent" EEG. PMID- 4194637 TI - Fourier analysis of on- and off-effects of evoked potentials. PMID- 4194639 TI - The development of sleep spindles during the first 2 years of life. PMID- 4194640 TI - The reaction of alpha activity during exercise. PMID- 4194641 TI - The value of the EEG recorded with open eyes for differential diagnosis of intracerebral processes: behaviour of physiological and pathological activity. PMID- 4194642 TI - Experiments on cholinergic mechanisms for the control of tonic and phasic components of REM sleep. PMID- 4194643 TI - EEG changes in Jakob-Creutzfeldt's disease under the influence of diazepam. PMID- 4194644 TI - EEG changes with facial injuries. PMID- 4194645 TI - Demonstration of technical novelties in the field of clinical electroencephalography. PMID- 4194646 TI - A study of axon reflexes in some neurological disorders. PMID- 4194647 TI - Auditory evoked responses. The basis for a promising objective audiometric test. PMID- 4194648 TI - The effect of diazepam (Valium) and nitrazepam (Mogadon) on picrotoxin induced seizures in rabbits. PMID- 4194649 TI - The size of the ventricular system. A comparative study between echoencephalography and pneumoencephalography. PMID- 4194650 TI - The epileptogenic effect of water-soluble contrast media. A search for less toxic substances. PMID- 4194651 TI - Mitochondrial RNA from cultured animal cells. II. A comparison of the high molecular weight RNA from mouse and hamster cells. AB - Discrete RNA fractions sedimenting slightly slower than 18s ribosomal RNA have been found in mitochondrial preparations from both hamster (BHK-21) and mouse (L 929) cells. This RNA could be separated into two components, present in approximately equimolar amounts, by prolonged zonal centrifugation or acrylamide gel electrophoresis. The hamster components had sedimentation constants averaging 16.8 and 13.4, and molecular weights (estimated by gel electrophoresis) averaging 0.74 and 0.42 x 10(6) daltons. Mixed labeling experiments showed that the mouse components sedimented and electrophoresed 3-6% more slowly than the corresponding hamster components. The RNA from both cell lines resembled mitochondrial ribosomal RNA from yeast and Neurospora in being GC poor, and in addition the larger and smaller components resembled each other in base composition. These results, taken with those of other recent studies, are compatible with the idea that our high molecular weight mitochondrial RNA is ribosomal; such RNA would then constitute a uniquely small size-class of ribosomal RNA. PMID- 4194652 TI - Osmium staining of endoplasmic reticulum and mitochondria in the rat adrenal cortex. AB - The zona fasciculata of the rat adrenal cortex synthesizes and secretes glucocorticoids. As observed after aldehyde fixation, the cells in this zone contain an extensive endoplasmic reticulum (ER), a small Golgi apparatus, a moderate number of lipid droplets, and abundant mitochondria with tubulovesicular cristae. Numerous areas within the endoplasmic reticulum and mitochondrial cristae appear clear. In addition, a small percentage of mitochondria encompasses large, clear areas. After immersion of finely minced adrenal cortex in unbuffered 2% OsO(4) (40-48 hr at 40 degrees C), deposits of osmium are seen within the Golgi apparatus, the entirety of the ER, and occasionally within mitochondria. In some mitochondria, the deposits are within cristae; in others, within vacuoles; in still others, in both cristae and vacuoles. These localizations correspond best to the clear areas found in aldehyde-fixed tissue. Osmium is not deposited in lipid droplets, in bar-containing inclusions, in mitochondrial matrix inclusions, or in the peripheral, outer mitochondrial spaces. Addition of zinc iodide to OsO(4) increases the amount of Golgi apparatus and mitochondrial staining. Adrenocorticotropin (ACTH) does not affect the localization of deposits; hypophysectomy decreases mitochondrial staining. This study (a) emphasizes the necessity for electron microscopic confirmation of osmium localization when this technique is used as a Golgi apparatus stain; and (b) suggests that the ER-staining pattern may be consistent in cells actively synthesizing steroids or steroid-like compounds. PMID- 4194653 TI - [Biochemical, physico-chemical and immunochemical aspects of Waldenstrom's macroglobulinemia]. PMID- 4194654 TI - Cytologic specificity of response to Moloney murine sarcoma virus as evident in a transplantable epithelioid neoplasm of the rat. PMID- 4194655 TI - Transformation and virus production in normal rat thymus cells and those infected with Moloney leukemia virus. PMID- 4194656 TI - Characteristics of a new inbred strain of mice (PBA) with a high tumor incidence: preliminary report. PMID- 4194657 TI - Immunoferritin and immunofluorescent studies with Epstein-Barr virus and herpes simplex virus by use of human sera and hyperimmune rabbit sera. PMID- 4194658 TI - Studies on the antigenic activities of yeasts. V. Effect of alpha-mannosidase digestion on the immunochemical properties of the mannan of Saccharomyces cerevisiae. PMID- 4194659 TI - Pituitary radiotherapy. PMID- 4194660 TI - A theory of self-nonself discrimination. AB - 1) Induction of humoral antibody formation involves the obligatory recognition of two determinants on an antigen, one by the receptor antibody of the antigen sensitive cell and the other by carrier antibody (associative interaction). 2) Paralysis of antibody formation involves the obligatory recognition of only one determinant by the receptor antibody of the antigen-sensitive cell; that is, a nonimmunogenic molecule (a hapten) can paralyze antigen-sensitive cells. 3) There is competition between paralysis and induction at the level of the antigen sensitive cell. 4) The mechanisms of low- and high-zone paralysis, and maintenance of the unresponsive state, are identical. 5) High-zone paralysis occurs when both the carrier antibody and the receptor antibody are saturated, so that associated interactions cannot take place. 6) The mechanisms of paralysis and induction for the carrier-antigen-sensitive cell are identical to those for the humoral-antigen-sensitive cell. 7) The formation of carrier-antigen-sensitive cells is thymus-dependent, whereas humoral-antigen-sensitive cells are derived from bone marrow. Since carrier antibody is required for induction, all antigens are thymus-dependent. 8) The interaction of antigen with the receptor antibody on an antigen-sensitive cell results in a conformational change in an invariant region of the receptor and consequently paralyzes the cell. As the receptor is probably identical to the induced antibody, all antibody molecules are expected to be able to undergo a conformational change on binding a hapten. The obligatory associated recognition by way of carrier antibody (inductive signal) involves a conformational change in the carrier antibody, leading to a second signal to the antigen-sensitive cell. 9) The foregoing requirements provide an explanation for self-nonself discrimination. Tolerance to self-antigens involves a specific deletion in the activity of both the humoral- and the carrier-antigen-sensitive cells. PMID- 4194661 TI - Neoplasia of the solitary kidney. PMID- 4194662 TI - The place of cryoprostatectomy. PMID- 4194663 TI - The newer anti-allergic agents. PMID- 4194664 TI - The antibody deficiency syndrome--clinical considerations. PMID- 4194665 TI - [Studies on extirpated and cultured tick tissues]. PMID- 4194666 TI - [Development and present state of bone plasty in the surgery of cleft palate]. PMID- 4194667 TI - The distribution of characters considered to be microforms of cleft lip and-or palate in a population of normal 18-21 year old subjects. PMID- 4194668 TI - An attempt to treat children with Pierre Robin syndrome orthopaedically. PMID- 4194669 TI - Surgical treatment of palmar and plantar keratosis. PMID- 4194670 TI - Pseudohermaphroditism. PMID- 4194671 TI - Hypospadias and a new method of its surgical treatment. PMID- 4194672 TI - One-stage operation for hypospadias. PMID- 4194673 TI - Contribution to the re-hydration of freeze-dried grafts. I. Re-hydration of rib bone grafts (short report). PMID- 4194674 TI - The revascularization of a free skin autograft. PMID- 4194675 TI - Experiment with many-layered skin grafts. PMID- 4194676 TI - The surgical treatment of skin damaged by radiation. PMID- 4194677 TI - The viability of cartilage transplants. PMID- 4194678 TI - [Indirect demonstration of acid mucopolysaccharides by means of sudan black B]. PMID- 4194679 TI - A histochemical study on the histogenesis of the mixed tumours of the human salivary glands. PMID- 4194680 TI - [Relation between metachromasia and optical amisotropy]. PMID- 4194681 TI - [Demonstration of cholinesterases with coupled staining]. PMID- 4194682 TI - [Double blind test of PPC for prostatic hyperplasia]. PMID- 4194683 TI - [Mechanism of production of auricular fibrillation (role of extrasystole)]. PMID- 4194684 TI - Phage-like particles from a lysogenic Thermomonospora. PMID- 4194685 TI - The action of visible radiation on the formation and properties of Saccharomyces ascospores. PMID- 4194686 TI - Enhancing effect of DEAE-Dextran on inclusion counts of an ovine Chlamydia (Bedsonia) in cell culture. PMID- 4194687 TI - Starch-iodide as a stain for peroxidases. PMID- 4194688 TI - [Serum protein profile of the patients with bronchial asthma]. PMID- 4194689 TI - Electron microscopical and immunological observations on the serum-hepatitis (S.H.) antigen in primary biliary cirrhosis. PMID- 4194690 TI - Combined treatment of parkinsonism with L-dopa and amantadine. PMID- 4194691 TI - Autologous transfusions in uraemic patients. PMID- 4194692 TI - "Free" iron loss in atrophic gastritis, post-gastrectomy states, and adult coeliac disease. PMID- 4194693 TI - Urinary steroid-excretion patterns after acute myocardial infarction. PMID- 4194694 TI - Long-term hepatic support by intermittent multi-species liver perfusions. PMID- 4194695 TI - Detection of thrombosis with iodine-125 fibrinogen. Data reassessed. PMID- 4194696 TI - Control of tuberculosis. PMID- 4194697 TI - Liver disease in ulcerative colitis. PMID- 4194698 TI - Direction for social science. PMID- 4194700 TI - Cholera on the Caspian. PMID- 4194699 TI - Screening for breast and gynaecological lesions. PMID- 4194701 TI - Design of skin flaps. PMID- 4194702 TI - Septic thrombophlebitis and venous cannulas. PMID- 4194703 TI - Screening for breast cancer. PMID- 4194704 TI - Screening for breast and gynaecological lesions. PMID- 4194705 TI - Child care in Czechoslovakia. PMID- 4194706 TI - Abortion analysis. PMID- 4194707 TI - "Central" venous pressure. PMID- 4194708 TI - Carrageenan and the human gut. PMID- 4194709 TI - Carrageenan: effects in animals. PMID- 4194710 TI - Medical care in the United States. PMID- 4194711 TI - Medical care in the United States. PMID- 4194712 TI - Medical care in the United States. PMID- 4194713 TI - Medical care in the United States. PMID- 4194714 TI - Sterilisation. PMID- 4194715 TI - Burkitt lymphoma and malaria. PMID- 4194716 TI - Hepatitis-Associated antigen. PMID- 4194717 TI - Streptokinase for pulmonary embolism. PMID- 4194718 TI - Streptokinase for pulmonary embolism. PMID- 4194719 TI - Intracranial venous thrombosis complicating oral contraception. PMID- 4194720 TI - Prevention of venous thrombosis. PMID- 4194721 TI - Animal sources of Escherichia coli in food. PMID- 4194723 TI - Swallowed neonatal endotracheal tube. PMID- 4194722 TI - Spoons and dip-slides. PMID- 4194724 TI - Plasma-catecholamine estimations. PMID- 4194725 TI - Glucagon and the heart. PMID- 4194726 TI - Coxsackie myocarditis of the newborn. PMID- 4194727 TI - Comparsion of antihypertensive agents. PMID- 4194728 TI - Dialysis circuit monitors. PMID- 4194729 TI - Serum-enzymes in dialysis patients. PMID- 4194730 TI - Carbenicillin in renal failure. PMID- 4194731 TI - Carbenicillin in renal failure. PMID- 4194732 TI - 48-hour kidney storage. PMID- 4194733 TI - Sputum viscosity in cystic fibrosis. PMID- 4194734 TI - Diabetes, diabetic angiopathy, and growth hormone. PMID- 4194735 TI - Etiology of Crohn's disease. PMID- 4194736 TI - Atypical reactions to bromsulphthalein (B.S.P.). PMID- 4194737 TI - Bedside diagnosis of the myasthenic syndrome. PMID- 4194738 TI - Stereostethoscope. PMID- 4194739 TI - Birth control and sex ratio. PMID- 4194740 TI - Anticonvulsant drugs and chromosomes. PMID- 4194741 TI - Cytostatic drugs and inflammation. PMID- 4194742 TI - James Harkness Margerison, M.B. St. And. PMID- 4194743 TI - John Marshall, M.C., T.D., M.B. Glasg., F.R.C.P.G., D.O.M.S. PMID- 4194744 TI - [Treatment of extrasystole and various rhythm troubles by 1215 S: clinical results in 80 patients]. PMID- 4194745 TI - [Transverse myelitis in the course of measles in a 7-year-old boy]. PMID- 4194746 TI - [Histochemistry and ultrastructure of Dubin-Johnson disease (report of 6 cases)]. PMID- 4194747 TI - [Clinical relations between endocrine exophthalmos and thyroid pathology]. PMID- 4194748 TI - [Some aspects of humoral and cellular immunity in acute viral hepatitis. Diagnostic and prognostic prospects]. PMID- 4194749 TI - [Immunological aspects of Sjogren's disease]. PMID- 4194750 TI - [Clinical and experimental data on the action of blockaders of adrenergic beta receptors in ectopic arrhythmias of the heart]. PMID- 4194751 TI - [Microbiological studies of the biotope "oral cavity"]. PMID- 4194752 TI - Genetical aspects in experimental induction of the cleft palate by cortisone in inbred strains of mice. A study of the segregation of the cleft palate and some of the genetically conditioned markers. PMID- 4194753 TI - Some considerations dealing with the role of the graft in the pathology of clinical transplantation. PMID- 4194754 TI - Epidemiologic studies on congenital malformations. Critical review and new conceptions. PMID- 4194755 TI - Contribution to the etiopathology of the cleft lip and palate. PMID- 4194756 TI - Application of tube pedicle flap for covering defects of the conjunctival sac. PMID- 4194757 TI - Classification of scarred neck contractures and their surgical therapy by methods of local plastic operation. PMID- 4194758 TI - Treatment of hypospadias. PMID- 4194759 TI - [Hematic transport of thyroxine in normal, hyperthyroid and hypothyroid subjects]. PMID- 4194760 TI - [Infantile metachromatic leukodystrophy (4 cases)]. PMID- 4194761 TI - Proteinaceous cysts of the ciliary epithelium. II. Their occurrence in nonmyelomatous hypergammaglobulinemic conditions. PMID- 4194762 TI - Dendritic fields of the retinal ganglion cells in the cat. PMID- 4194763 TI - [Somatic sensory properties of red nucleus neurons]. PMID- 4194764 TI - [Treatment of intractable pain due to cancer]. PMID- 4194765 TI - [Justification of a prostatic adenectomy technic based on 650 surgically treated cases]. PMID- 4194766 TI - Continued studies on the axonal transport of nerve proteins to muscle. PMID- 4194767 TI - The effect of hydrocortisone on immunoglobulin metabolism. AB - The serum concentration of all subclasses of IgG (gamma(2)A, gamma(2)B, and gamma(1)) as well as IgA and IgM were reduced in normal and low pathogen mice receiving hydrocortisone acetate. Turnover studies using (131)I-labeled gamma(2)A subclass of IgG demonstrated that high dose corticosteroids cause a significantly shortened survival (increased catabolic rate) which contributes to the observed hypogammaglobulinemia. This increase in fractional catabolism is not due to excess loss in the urine or stool but reflects an increase in endogenous catabolism. PMID- 4194768 TI - Dihydrotestosterone in prostatic hypertrophy. I. The formation and content of dihydrotestosterone in the hypertrophic prostate of man. AB - To explore the relation between androgens and prostatic hypertrophy in man, the concentrations of testosterone, dihydrotestosterone, and androstenedione and the rate of conversion of testosterone to dihydrotestosterone have been measured in normal and hypertrophic prostate tissue. First, a double isotope derivative technique was adapted for the measurement of tissue androgen content in 15 normal and 10 hypertrophic prostates. Although there was no significant difference in the content of androstenedione and testosterone between the two types of tissue, the content of dihydrotestosterone was significantly greater in the hypertrophic tissue (0.60 +/-0.10 mug/100 g) than in the normal glands (0.13 +/-0.05 mug/100 g). Second, a regional study was performed in three normal prostates and four glands with early hypertrophy, and it was demonstrated that the dihydrotestosterone content was two and three fold greater in the periurethral area where prostatic hypertrophy usually commences than in the outer regions of the gland. Finally, the rate of conversion of testosterone to dihydrotestosterone has been measured under standardized conditions in tissue slices from 4 normal and 20 hypertrophic prostates. There was no significant difference in the rate of dihydrotestosterone formation between the two types of gland (6.0 +/-0.8 and 7.8 +/-0.5 mumumoles/15 mg of tissue per hr). While the mechanism by which dihydrotestosterone accumulation occurs remains unexplained, it is possible that the local accumulation of dihydrotestosterone may be involved in the pathogenesis of prostatic hypertrophy in man. PMID- 4194769 TI - Dihydrotestosterone in prostatic hypertrophy. II. The formation and content of dihydrotestosterone in the hypertrophic canine prostate and the effect of dihydrotestosterone on prostate growth in the dog. AB - Three types of studies have been performed in immature, mature, and hypertrophic prostate glands of the dog. First, the concentrations of testosterone and dihydrotestosterone have been measured in the three types of gland. Dihydrotestosterone was the predominant hormone recovered in all prostates studied and was present in approximately five times higher concentration in the hypertrophic as compared to the other types of dog prostate. Second, pharmacological doses of dihydrotestosterone were administered to castrated dogs for 9 months and resulted in a distinct acceleration of prostatic growth as compared to testosterone treatment. Third, the rates of formation and degradation of dihydrotestosterone were measured in normal and hypertrophic tissue and were found to be essentially the same. These observations suggest that dihydrotestosterone accumulation may be causally linked to the development of canine prostatic hypertrophy. However, the mechanism by which dihydrotestosterone accumulates in the prostate remains to be determined. PMID- 4194770 TI - [Role of histamine liberated during the shock induced in dogs by the injection of incompatible heterologous red blood cells]. PMID- 4194771 TI - [Action of some enzyme inhibitors on the conjugation of B.S.P. in bile. (Perfused liver of rats)]. PMID- 4194772 TI - Promising trends in neuroscience. PMID- 4194773 TI - Immunoglobulin allotypic determinants on rabbit lymphocytes. PMID- 4194774 TI - [Histaglobin treatment of bronchial asthma in children]. PMID- 4194775 TI - [Dissociated immunoglobulin deficiency: immunoglobulin G and A deficiency (IgG and IgA) deficiency with immunoglobulin M increase (IgM)]. PMID- 4194777 TI - [Immunofluorescence in visceral lupus erythematosus]. PMID- 4194776 TI - Electromechanical correlations in the mammalian heart muscle. PMID- 4194778 TI - [Passive immunization of children in the course of severe diseases with a gamma globulin preparation (Gamma Venin) for intravenous use]. PMID- 4194779 TI - [Lymphatic vessels in the human pancreas]. PMID- 4194780 TI - [Obtainment and clinical use of human anti-smallpox gamma-globulin with directed action]. PMID- 4194781 TI - [Anti-aorta antibodies and aortic lesions induced by repeated injections of aortic extracts (study in rabbits)]. PMID- 4194782 TI - [Refsum's disease. Case report with ophthalmological data]. PMID- 4194783 TI - [Experimentation with a new heparinoid administered by cutaneous route in medical practice]. PMID- 4194784 TI - [Investigations about biological actions of a lipolytic peptide isolated from pig pituitaries (fraction H). II. Behaviour of lipids, glucose, creatinine, BUN, protein and electrolytes in serum of rabbits within 24 hours after a single injection of fraction H]. PMID- 4194785 TI - [Investigations about biological actions of a lipolytic peptide isolated from pig pituitaries (fraction H). 3. Effect on enzyme activities in adipose tissue and liver]. PMID- 4194786 TI - [Enzyme activity in the human placenta during normal and disturbed pregnancy. I. Glutamate oxalacetate (GOT) and Glutamate pyruvate transaminase (GPT) during normal pregnancy]. PMID- 4194787 TI - Behaviour of mast cells in the skin of mice treated with benzpyrene. PMID- 4194788 TI - Biological variables associated with mothers of children affected with the G1 trisomy syndrome. (Down's syndrome). PMID- 4194789 TI - Multiplication of fowlpox virus in chicken embryo fibroblastic cell cultures. PMID- 4194790 TI - [Pituitary adenoma with thyrotropic cells with hyperthyroidism]. PMID- 4194791 TI - [Cytological study of the distal lobe of the pituitary gland of Alytes obstetricans Laur tadpole, during larval development]. PMID- 4194792 TI - [Influence of airionization on the hypophysis of the albino rat]. PMID- 4194794 TI - [Histochemical data on the neurosecretion of Carausius morosus (phasmid Orthoptera)]. PMID- 4194793 TI - [Histopathological in the hypophysis in 6 cases of hemochromatosis]. PMID- 4194795 TI - [Partial sequence of fragment Fc' of mouse clonal immunoglobulin]. PMID- 4194796 TI - Cross-reactions between human and animal plasma proteins. II. The influence of structural and functional factors. PMID- 4194797 TI - Effects of Escherichia coli on germ-free and gnotobiotic pigs. II. Serum proteins and antibodies. PMID- 4194798 TI - Observations on the immune globulin levels of neonatal calves and their relationship to disease. PMID- 4194799 TI - Hyaline arteriolosclerosis in wild animals. PMID- 4194800 TI - Effect of histomoniasis on the serum proteins of the fowl. PMID- 4194801 TI - Microprobe analysis of Protargol stain deposition in two protozoa. PMID- 4194802 TI - [The dynamics of cardiac contraction in the respiratory phase of respiration in patients with hypertension]. PMID- 4194803 TI - [Phytoresponsiveness and cytogenetics in non-tumoral lymphocytic pathology]. PMID- 4194804 TI - [Immunological aspects during Salmonella Munchen infection in newborn infants and sucklings]. PMID- 4194805 TI - [Radial immunodiffusion and the selectivity index of massive proteinuria. Anatomo clinical correlations]. PMID- 4194806 TI - [Diagnostic value of the alpha 2 globulin and tetracycline fluorescence test in malignant diseases of the respiratory system]. PMID- 4194807 TI - [Long-term therapeutic results in Whipple's disease: 4 personal cases]. PMID- 4194808 TI - [Dihydrostreptomycin]. PMID- 4194809 TI - [Reaction of endogenous and exogenous iodine compounds in the serum with a basic ion exchanger]. PMID- 4194810 TI - Elongated structures present in cells infected with influenza viruses. PMID- 4194811 TI - [Equine arteritis virus: multiplication in BHK 21-cells buoyant density and electron microscopical demonstration]. PMID- 4194812 TI - [Bone tumors. 4. I. Treatment of tumor metastasis. II. Microvascularization of bony tumors]. PMID- 4194813 TI - A research standard for human serum immunoglobulins IgG, IgA and IgM. AB - A pooled human serum, partly diluted, has been distributed into ampoules and freeze-dried in several batches. The freeze-dried material has been examined in an international collaborative assay and certain properties have also been estimated in individual laboratories.On the basis of these tests this material was considered to be suitable for use as a standard for the estimation of IgG, IgA and IgM for clinical purposes using the single-radial-diffusion or similar techniques. Greater uniformity of results than is obtained at present should be achieved if this material were in general use.Estimates of immunoglobulins from different laboratories using this material as a standard showed small but significant variability. This variability was probably related to the heterogeneity of immunoglobulins and of antisera, and it limits the precision of immunoglobulin estimations by techniques at present in use.Batches of this material have been distributed to various centres. 67/68 has been established as the British research standard for human serum immunoglobulins IgG, IgA and IgM for which the unit of potency is defined as the activity present in 0.8147 mg of dry powder. The average activity per ampoule of 67/86 is 100 units of IgG, IgA and IgM. The average activities of other related preparations have been estimated. PMID- 4194814 TI - Lack of seasonal variation in protein-bound iodine. PMID- 4194815 TI - [Therapy using sex hormones]. PMID- 4194816 TI - Iodine metabolism in autoimmune thyroiditis. PMID- 4194817 TI - [Preliminary clinical trials of a new histidine-decarboxylase inhibitor in the therapy of prurigo]. PMID- 4194818 TI - Indications for prostatectomy. PMID- 4194819 TI - [Mosphological study of keratoconus]. PMID- 4194820 TI - Studies on cytophilic antibodies. A mouse serum "antibody" having an affinity for macrophages and fast alpha-globulin mobility. PMID- 4194821 TI - Chemical linkage of polycyclic hydrocarbons to deoxyribonucleic acids and polynucleotides in aqueous solution and in a buffer-ethanol solvent system. PMID- 4194822 TI - [Identification by means of immunofluorescence of glucagon secreting cells in thin sections of epoxy-resin embedded islet tissue (rat, frog)]. PMID- 4194823 TI - [Controlled freeze-drying of cryostat sections]. PMID- 4194824 TI - Ultraviolet absorbing dyes as histochemical reagents. PMID- 4194825 TI - Volume changes accompanying the antibody-antigen reaction. PMID- 4194826 TI - Characteristics of antigenic determinants of intact cell surfaces. PMID- 4194827 TI - Juvenile rheumatoid arthritis--a serologic survey of 200 consecutive patients. PMID- 4194828 TI - Appearance and distribution of ectromelia virus inclusion bodies in experimentally infected mice. PMID- 4194830 TI - Spontaneous renal carcinoma in a New Zealand white rabbit. PMID- 4194831 TI - Two ways to protein. PMID- 4194832 TI - Measles. PMID- 4194833 TI - Familial metaphyseal dysplasia. PMID- 4194834 TI - Blood-groups and nasopharyngeal carcinoma. PMID- 4194835 TI - Prevention of venous thrombosis. PMID- 4194837 TI - Drastic cures for obesity. PMID- 4194838 TI - Side-effects of insulin contaminating commercial glucagon. PMID- 4194839 TI - Smoking, air pollution, bronchitis, and population mobility. PMID- 4194840 TI - Hydroxylysinuria. PMID- 4194841 TI - Cryotherapy in head and neck cancer. PMID- 4194842 TI - Early diagnosis of lung cancer by cytology. PMID- 4194843 TI - Electrophoresis and immunodiffusion techniques on cellulose acetate membrane. PMID- 4194844 TI - [Prevention of decibitus ulcer]. PMID- 4194845 TI - [Severe whooping cough in infants. Current aspects]. PMID- 4194846 TI - [Britical study of the therapy of acute severe cytolytic hepatitis]. PMID- 4194847 TI - [Renal cancer]. PMID- 4194848 TI - [Social security: general aspects. Health insurance]. PMID- 4194849 TI - [New surgical service at the Peupliers Hospital]. PMID- 4194850 TI - [Developments in the cost of health for the nurse]. PMID- 4194851 TI - [Development and trends in maternal-child welfare towards the idea of family welfare]. PMID- 4194852 TI - [Child abuse]. PMID- 4194853 TI - [Where are the students 15 years later?]. PMID- 4194854 TI - [Occupational work for able-bodied elderly persons; an experience]. PMID- 4194855 TI - [Prevention of communicable diseases in schools]. PMID- 4194856 TI - [Intravenous urography]. PMID- 4194857 TI - Some morphological features of bluetongue virus. PMID- 4194858 TI - Diagnosis of hyperthyroidism. Statistical evaluation of laboratory and clinical criteria. PMID- 4194859 TI - Simple method for quantitive densitometry of polyacrylamide gels using fast green. PMID- 4194860 TI - The genetically determined binding of alcian blue by a minor fraction of yeast cell walls. PMID- 4194861 TI - The dissociation in vitro of the alpha- and beta-lipoprotein components of human and rat very low density lipoproteins. PMID- 4194863 TI - Selecting content in medical-surgical nursing for the associate degree nursing program. PMID- 4194862 TI - The wheezing patient. Problems in the differential diagnosis of allergic bronchial asthma. PMID- 4194864 TI - [Studies on the constituents of Lyonia ovalifolia Drude var. elliptica Hand. Mazz. IX. Structure of lyoniol-A(lyoniatoxin), the main component of the toxic principles. (1)]. PMID- 4194865 TI - Selective gamma-g globulin deficiencies in patients with recurrent pyogenic infections. PMID- 4194866 TI - [Familial dysgammaglobulinemia in a case of lupous erythematovisceritis]. PMID- 4194867 TI - Synthesis of immunoglobulin heavy and light chains by the free ribosomes of a mouse plasma cell tumor. AB - Free and membrane-bound ribosomes have been isolated from a mouse plasma cell tumor secreting immunoglobulins, and allowed to synthesize proteins under cell free conditions. Analysis of the products of synthesis by autoradiography of immunoelectrophoresis and peptide maps indicates that both types of ribosomes synthesize heavy and light immunoglobulin chains. PMID- 4194868 TI - Implications of heavy chain disease protein sequences for multiple gene theories of immunoglobulin synthesis. AB - The sequence of the amino-terminal 34 amino acids of gamma-heavy chain disease (gamma-HCD) protein Hi is homologous with the amino-terminal region of immunoglobulin heavy chains. gamma-heavy chain disease is smaller than a normal gamma-chain, but has the carboxy-terminal composition expected for gamma-chains and must, therefore, contain an internal deletion. Comparison of the Hi sequence with that of gamma-heavy chain disease Zu, which also has an internal deletion, indicates that the site of internal deletion is not a constant characteristic of gamma-heavy chain disease proteins. Heavy chains can be assigned to subgroups on the basis of variable region sequences. The variable regions of Hi and one other protein differ significantly from those determined for other heavy chains, and these two proteins are assigned to a new heavy chain variable region subgroup, V(HIV). It has been suggested that single immunoglobulin heavy chains are the products of two separate structural genes and that variable region genetic information is translocated and integrated into common region information. These multiple gene theories make no prediction as to whether DNA or RNA is translocated. gamma-heavy chain disease proteins provide unique information that indicates that if translocation is required for the production of immunoglobulin heavy chains, it is DNA, not RNA, that is translocated. PMID- 4194869 TI - Thyroidal iodine and proteins in autoimmune thyroiditis. PMID- 4194870 TI - The serum proteins identified by means of the Laurell crossed electrophoresis. PMID- 4194871 TI - Metabolism of bence jones proteins in non-myeloma patients with normal renal function. PMID- 4194872 TI - [Intubation technic in the patients with inoperable esophageal cancer]. PMID- 4194873 TI - [The diagnosis of gonorrhea in females]. PMID- 4194874 TI - [Secondary and tertiary actinomycins. II. Conformation and NMR spectrum of pentapeptide lactone]. PMID- 4194875 TI - [Penetration of gamma-globulins from mother to fetus in the rabbit (liuminescent serologic study)]. PMID- 4194876 TI - [DNA replication under conditions of inhibited synthesis of RNA and protein (cytophotometric and autoradiographic study)]. PMID- 4194877 TI - [Enuresis nocturna. Genesis and treatment]. PMID- 4194878 TI - Electron microscope studies of sperm incorporation into the golden hamster egg. PMID- 4194879 TI - Evaluation of laboratory methods for detecting acute TRIC agent infection. PMID- 4194880 TI - Immunoglobulin E-mediated respiratory responses of subhuman primates. Reproducibility and effect of certain pharmacologic agents. PMID- 4194881 TI - [Technical modifications of the bidimensional immunoelectrophoresis method. Application to various biological fluids]. PMID- 4194882 TI - Pulmonary responses to inhaled particles. Role of vasoactive substances. PMID- 4194884 TI - Evaluation of the triiodothyronine suppression test in the treatment of Graves' disease. PMID- 4194883 TI - [Primary melanomas of the nasal fossae and mouth. Histological study of 19 cases]. PMID- 4194885 TI - Metabolic activities of thyroid glands from tapazole treated rats. PMID- 4194886 TI - A whole-mount cholinesterase technique for demonstrating corneal nerves: observations in the albino rabbit. PMID- 4194887 TI - Further experimental studies of dynamic propositions in psychoanalysis. On the function and meaning of regressive thinking. PMID- 4194888 TI - The development of the child's sense of his sexual identity. PMID- 4194889 TI - Effect of water pressure irrigation on stainable material on the teeth. PMID- 4194890 TI - The extent of ischemic damage in the myocardium of the cat after permanent and temporary coronary occlusion. PMID- 4194891 TI - Palliative esophagogastrostomy for inoperable carcinoma of the esophagogastric junction. PMID- 4194892 TI - Plasma protein changes in mild thermal trauma. PMID- 4194893 TI - [Technic of palliative operations in liver alveococcosis]. PMID- 4194894 TI - [Current status of immunological prophylaxis of infectious diseases]. PMID- 4194895 TI - Adult-type Gaucher's disease: a secondary disorder of iron metabolism. PMID- 4194896 TI - [Disamide--an antiarrhythmic agent in cardiovascular diseases]. PMID- 4194897 TI - [Treatment of acute intoxication with anticoagulants]. PMID- 4194898 TI - [The immuno-fluorescent method in study of lupus erythematosus]. PMID- 4194899 TI - [Morphological and immunohistochemical characteristics of nephropathies in systemic lupus erythematosus]. PMID- 4194900 TI - Pick's disease with compound intraneuronal inclusion bodies. PMID- 4194901 TI - Benign fibro-osseous lesions of the mandible and maxilla. A review of 35 cases. PMID- 4194902 TI - Mesonephroma ovarii (hypernephroid carcinoma). Light microscopic and ultrastructural study of a case. PMID- 4194903 TI - [Hormone therapy of prostatic hypertrophy--present status and the future]. PMID- 4194904 TI - [Prostatic hypertrophy and cancer from the metabolic aspect]. PMID- 4194905 TI - [Atypical palliative surgery for several congenital heart defects]. PMID- 4194906 TI - Guinea pig ovary and testis: demonstration of common gonad specific antigens in the ovary and testis. PMID- 4194907 TI - A study of the late form (type Lundborg) of progressive myoclonic epilepsy. PMID- 4194908 TI - The judgment of vowel quality. PMID- 4194909 TI - [Staining of fat inclusions in entomophthorous fungi (Entomophthoraceae, Phycomycetes) by a pigment from Serratia marcescens Bizio]. PMID- 4194910 TI - Discharge of the terminally-ill patient. PMID- 4194911 TI - [Use of Ovosiston in prevention of bleeding after electroconization]. PMID- 4194912 TI - Localization of Treponema pallidum immobilizing antibody in human immunoglobulins. PMID- 4194914 TI - Astrocytes in formalin-fixed paraffin sections. A new modification of Cajal's technic and comparison with the hematoxylin and eosin method. PMID- 4194913 TI - [The serum complement titer in active chronic viral hepatitis]. PMID- 4194915 TI - [Transvesical electroresection of prostate adenomas and stenosing formations of the neck of the urinary bladder]. PMID- 4194916 TI - [Complications following prostatic adenomectomy]. PMID- 4194917 TI - Myocardial necrosis induced by isoproterenol in rats. Changes in serum protein, lipoprotein, lipids and glucose during active necrosis and repair in arteriosclerotic and nonarteriosclerotic animals. PMID- 4194918 TI - [The cigarette as source of carbon monoxide]. PMID- 4194919 TI - [Changes in silver impregnation of nerve elements following the effect of antimonoaminoxidase substances on the organism]. PMID- 4194920 TI - [Immunosuppression of anti-Rh antibodies: mechanism of action and times of administration of the anti-D immunoglobulins]. PMID- 4194921 TI - [Maternal-fetal exchange of gamma globulins in different species of mammals]. PMID- 4194922 TI - [Serum complement in the infants of mothers treated with immunodepressive agents]. PMID- 4194923 TI - [Experimental induction of passive cutaenous anaphylaxis with intraperitoneal injection of antigens]. PMID- 4194924 TI - [Estrin's synchronization in guinea pigs]. PMID- 4194925 TI - Excretion of immunoglobulins in Burkitt's lymphoma. AB - IgM was detected in the urines of 4 out of 17 patients with Burkitt's lymphoma. This IgM emerged from Sephadex G 200 column in two different peaks strongly suggesting sub-units of the intact molecule. IgM was not detected in any of the control urines. The total protein excreted in the urine of Burkitt's lymphoma patients is higher than in controls and may be due to renal involvement. Intact IgA and IgG as well as fragments of IgG were present in the urines of all Burkitt patients as well as in controls. Six of 16 Burkitt's lymphoma patients had reduced serum levels of IgG. Four of these also had reduced serum IgM. The low mean concentration of serum IgM confirms our previous studies. PMID- 4194926 TI - The management of terminal carcinoma with oral potassium permanganate. AB - Oral potassium permanganate has been used in the management of terminal carcinoma in three patients. Symptomatic improvement occurred in all three, with elimination of oral foetor in one patient and diminished requirement of analgesics in the other two. The mental state of each patient was improved and normal activities were resumed. PMID- 4194927 TI - The effect of tumour growth on immune competence. A study of DMBA mammary carcinogenesis in the rat. AB - Circulating antibody response to flagella antigen has been measured in three groups of Sprague-Dawley rats after feeding with 7.12.DMBA in an attempt to differentiate carcinogen and tumour growth as causative agents in the depression of immune response seen in these animals. DMBA fed female rats developing tumours had progressive depression of both primary and secondary response as compared to control animals, and 7S and 19S antibody fractions were equally affected. Removal of tumours did not result in recovery of response. Attempts to prevent tumour development by mammectomy after DMBA feeding were unsuccessful, but the similar number of tumours found in this group was associated with an equal degree of antibody depression to that seen in the first experiment. Male animals fed DMBA did not develop malignant tumours, and showed no depression of immune response. Results suggest that tumour development plays a part in the depression of circulating antibody response seen in these animals, but that it is not directly related to the number of tumours, and is not reversible by tumour excision. PMID- 4194928 TI - A staining technique to demonstrate erythrocyte refractile bodies in cat blood. PMID- 4194929 TI - The effect of haemoglobin on the detection of immunoglobulins in calf sera. PMID- 4194930 TI - Preparation and purification of horse antihuman lymphocyte globulin (ALG). PMID- 4194931 TI - [No. 205. Elementary prescriptions for the prevention and therapy of poliomyelitis]. PMID- 4194932 TI - [Acute and chronic effects of air pollution produced by traffic at a busy crossing on lung function in humans. Determination of CO, Hb and Pb in blood]. PMID- 4194933 TI - Palliative treatment of dysphagia in advanced carcinoma of stomach. PMID- 4194934 TI - Cardiac transplantation in man. 8. Survival and function. PMID- 4194935 TI - Controlled trial of cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood. PMID- 4194936 TI - Ovulation stimulation. Problems of prediction of response to gonadotrophins. PMID- 4194937 TI - Coronary prognostic index for predicting survival after recovery from acute myocardial infarction. PMID- 4194938 TI - Hypercholesterolaemia in borderline hypothyroidism. Stage of premyxoedema. PMID- 4194939 TI - Iron therapy in patients on maintenance haemodialysis. PMID- 4194940 TI - Hyperaluminaemia from aluminum resins in renal failure. PMID- 4194941 TI - Further observations on Kveim test in Crohn's disease. PMID- 4194942 TI - Further assessment of the venous-compression test in hyperparathyroidism. PMID- 4194943 TI - Subacute sclerosing panencephalitis: a zoonosis following aberrant measles. PMID- 4194944 TI - Semiautomatic electrocardiographic monitoring. PMID- 4194945 TI - Pneumatic intermittent-compression legging simulating calf-muscle pump. PMID- 4194946 TI - Laryngeal strombomicroscope. PMID- 4194947 TI - Immunosuppression in nephritis. PMID- 4194948 TI - Treatment of infertility. PMID- 4194949 TI - Children in isolation units. PMID- 4194950 TI - Epidemiology of gallstone disease. PMID- 4194951 TI - Hopeful regulations. PMID- 4194952 TI - Injuries to knee ligaments and hypermobility. PMID- 4194953 TI - Initiation of protein synthesis. PMID- 4194954 TI - Housewives' hands. PMID- 4194955 TI - Drift from science. PMID- 4194956 TI - Revolution in community welfare. PMID- 4194957 TI - A group home project. PMID- 4194958 TI - Medical care in the United States. PMID- 4194960 TI - "Renpenning" syndrome. PMID- 4194959 TI - Intermittent complete heart-block. PMID- 4194961 TI - Effect of anticonvulsant drugs on insecticide residues. PMID- 4194962 TI - Phenobarbitone in posthepatitic unconjugated hyperbilirubinaemia. PMID- 4194963 TI - Portable heparin injector. PMID- 4194964 TI - Beta-hydroxyisovaleric aciduria and beta-methylcrotonylglycinuria: a new inborn error of metabolism. PMID- 4194965 TI - Screening for phenylketonuria. PMID- 4194966 TI - An unusual case of rabies. PMID- 4194967 TI - Immunoglobulins in schizophrenic patients. PMID- 4194968 TI - Lithium distribution in the brains of two manic patients. PMID- 4194969 TI - Congenital chromosome abnormalities and leukaemia. PMID- 4194970 TI - Great corn mystery. PMID- 4194971 TI - The E.E.G. in herpes-simplex encephalitis. PMID- 4194973 TI - Early effect of humanae vitae? PMID- 4194972 TI - Treatment of primary polycythaemia. PMID- 4194974 TI - Studies from the hair. PMID- 4194975 TI - Tetanus: new treatment and prophylaxis. PMID- 4194976 TI - Smoking and frusemide diuresis. PMID- 4194977 TI - Corticotrophin-induced growth-hormone release. PMID- 4194978 TI - Is lyonisation total in man? PMID- 4194979 TI - Multiply resistant staphylococci. PMID- 4194980 TI - Accelerated nucleic-acid synthesis in uraemic lymphocytes. PMID- 4194981 TI - Transformation of xerodermapigmentosum cells by SV40. PMID- 4194982 TI - G.M.C. retention fee. PMID- 4194983 TI - Hypocholesterolaemia in anaemia. PMID- 4194984 TI - [Evaluation of cytostatic effects in rectal tumors]. PMID- 4194985 TI - The diagnosis and treatment of children with learning and developmental problems. A community service for medical group practice. PMID- 4194986 TI - [Acute fatal boric acid poisoning by irrigation of the bladder following prostatectomy]. PMID- 4194987 TI - [Indications and results of clinical radiotherapy]. PMID- 4194988 TI - [The duration of the Q-T phase in hyperthyroidism before and after treatment with cardiac glycosides]. PMID- 4194989 TI - Albumin metabolism and gastrointestinal protein loss in children with nephrotic syndrome. PMID- 4194990 TI - Atypical changes in thyroid follicular cells secondary to radioiodine. PMID- 4194991 TI - [Whipple's disease]. PMID- 4194992 TI - Experimental atherosclerosis in normal and subdiabetic rabbits. I. Short-term studies. PMID- 4194993 TI - Angiotoxic activity of 4'fluoro-10-methyl-1,2-benzanthracene in the rat. PMID- 4194994 TI - Lysosomal site of crystalline deposits in cystinosis as shown by ferritin uptake. PMID- 4194995 TI - Spectrum of aging changes in temporal arteries. Its significance, in interpretation of biopsy of temporal artery. PMID- 4194996 TI - Naturally occurring human antibodies to pepsin-digested IgA. PMID- 4194997 TI - Benign prostatic hypertrophy and uraemia. A review of 315 cases. PMID- 4194999 TI - [Combined enzyme and hemagglutination studies for the detection of hepatitis epidemic and the effect of gamma globulin]. PMID- 4194998 TI - Recurrence of hyperthyroidism shortly after return of normal suppressibility by triiodothyronine. PMID- 4195001 TI - Argyrophilic cells of the dog pancreas following different silver stains. PMID- 4195000 TI - [Immunosuppressive long term therapy of visceral lupus erythematosus]. PMID- 4195002 TI - [Renal amyloidosis in lepromatous leprosy. Case report]. PMID- 4195003 TI - Detection and characterization of DNA in mixed (IgG-IgM) cryoglobulins. PMID- 4195004 TI - The measurement of serum immunoglobulin E levels in healthy adults and children and in children with allergic asthma. PMID- 4195005 TI - A study on the detection of human reagins with rat peritoneal mast cells. PMID- 4195006 TI - The immune responses and lymphoid tissues of neonatally thymectomized, X irradiated mice. PMID- 4195007 TI - Serum lipoproteins of rats bearing transplanted Morris hepatoma 7777. PMID- 4195008 TI - Hematologic findings in certain small cetaceans. PMID- 4195009 TI - Naturally occurring cutaneous streptothricosis in a white-tailed deer (Odocoileus virginianus). PMID- 4195010 TI - Type A enterotoxemia in captive wild goats. PMID- 4195011 TI - Subacute sclerosing panencephalitis-like syndrome in the adult baboon (Papio sp.). PMID- 4195012 TI - The disposition of proteinpolysaccharide in the epiphysial plate cartilage of the young rabbit. PMID- 4195013 TI - A multiple-choice audio-visual discrimination apparatus with quick interchange display and response panels. PMID- 4195014 TI - Medullary tractotomy. A surgical procedure providing relief from severe pain due to cancer of head and neck. PMID- 4195015 TI - A comparative study of blood fibrinolytic activity in normal women, pregnant women and women on oral contraceptives. PMID- 4195016 TI - [Laboratory service of the clinic of the I Moscow Order of Lenin and the Red Banner of Labor Medical Institute named after I. M. Sechenov]. PMID- 4195017 TI - [Contemporary methods of studying megakaryocytes (review of the literature)]. PMID- 4195019 TI - [Clinical significance of determining alkaline phosphatase in peripheral blood leukocytes in infectious hepatitis and obstructive jaundice]. PMID- 4195018 TI - [Several cytochemical changes in blood neutrophils in posthemorrhagic anemia]. PMID- 4195020 TI - [Levels of acid and alkaline phosphatase in peripheral blood leukocytes of healthy mice and rats]. PMID- 4195021 TI - [Comparative evaluation of several methods for the determination of serum seromucoid]. PMID- 4195022 TI - [Critical evaluation of clinico-laboratory methods to determine "permeability" of blood vessels according to the filtration of water and proteins]. PMID- 4195023 TI - [Determination of serotonin in gastric juice by a fluorometric method]. PMID- 4195024 TI - [Extraction-photometric determination of zinc in erythrocytes]. PMID- 4195025 TI - [Obtainment of the gamma-G-globulin fraction with various isoelectric points with the method of electroconvection]. PMID- 4195026 TI - [Photonephelemetric method of determining beta-lysins in serum]. PMID- 4195027 TI - [Use of the passive hemagglutination reaction for the diagnosis of erysipelas]. PMID- 4195028 TI - [Several indices of the morphological composition of the blood and natural immunity in healthy white rats]. PMID- 4195029 TI - [Quantitative determination of antibodies in immune serums by means of the complement fixation reaction]. PMID- 4195030 TI - [Method of detecting parapoliomyelitic virus in sewage sedimentation]. PMID- 4195031 TI - [Use of O-serums in the laboratory diagnosis of intestinal coli infections]. PMID- 4195032 TI - [Identification of Vibrio cholerae fermenting arabinose]. PMID- 4195033 TI - [Use of Levina's method for the isolation and identification of fungi of the genus Candida in a routine laboratory]. PMID- 4195035 TI - [Lyophilization of granular preparations]. PMID- 4195034 TI - [Detection of bacteriuria by way of determining urine catalase]. PMID- 4195036 TI - [Multiple sclerosis. 4. Changes of immunoglobulins in the cerebrospinal fluid]. PMID- 4195037 TI - Gastric cytology. PMID- 4195038 TI - Assessing immunization procedures. PMID- 4195039 TI - [Thyrotoxicosis and psychosis]. PMID- 4195040 TI - Rapid method for separation of blood cells. PMID- 4195041 TI - Endocrine profile of a new progestational steroid. 4,6-dichloro-17 alpha-hydroxy pregna-4,6-diene-3,20-dione, acetate (Ro 7-2133). PMID- 4195042 TI - [Studies on the concentration of aminoglycoside antiboitics in the labyrinthine fluids and their significance for the specific ototoxicity of the aminoglycoside antibiotics]. PMID- 4195043 TI - [Studies on male infertility. Lactic dehydrogenase isozymes of the seminal plasma in infertile men]. PMID- 4195044 TI - Successes and failures in the search for antibiotics. PMID- 4195045 TI - [Histopathology of brain death]. PMID- 4195047 TI - In vivo histamine levels with hypoxia and compound 48-80. PMID- 4195046 TI - Recent progress in pharmacogenetics. PMID- 4195048 TI - Demonstration of the fenesrated membrane (membrana fenestrata) in the human arterial wall by stained tissue segment. PMID- 4195049 TI - The basis of differential staining of ascospores and vegetative cells of yeasts. PMID- 4195050 TI - [Corticosteroids in the prevention and therapy of conduction disorders caused by myocardial infarct]. PMID- 4195051 TI - [The reaction on starvation of A'-neurosecretory cells in silkworms during facultative feeding]. PMID- 4195052 TI - Studies on the immunogenicity of antigen-antibody precipitates. II. The suppressive effect of anti-carrier and anti-hapten antibodies on the immunogenicity of dinitrophenylated human gamma G globulin. PMID- 4195053 TI - Cytochemical detection of cytochrome oxidase activity in bacteria. PMID- 4195055 TI - Physical and biological properties of dengue-2 virus and associated antigens. AB - Dengue virus suspensions from mouse brain and cell culture were fractionated into three components by rate zonal centrifugation in sucrose gradients. Infectious virus sedimented in a single zone and possessed hemagglutinating (HA) and complement fixing (CF) activity. Electron micrographs showed the virion to be a spherical particle 48 to 50 nm in diameter with 7-nm spherical structures on its surface. Buoyant density in CsCl of virions from mouse brain was estimated at 1.22 g/cm(3) and from cell culture at 1.24 g/cm(3). During centrifugation of virions in CsCl, an additional HA component appeared with a buoyant density of 1.18 g/cm(3). It was shown in electron micrographs to consist of virion fragments. A noninfectious component with HA and CF activity sedimented in sucrose more slowly than intact virus, had a buoyant density of 1.23 g/cm(3) in CsCl, and appeared as "doughnut" forms measuring 13.8 to 14 nm in diameter. A third component, with CF activity and no HA activity, sedimented very little in sucrose gradients. Particles of the same size and shape as the spherical subunits on the surface of the virion were observed in electron micrographs. PMID- 4195054 TI - Morphology and entry of enveloped and deenveloped equine abortion (herpes) virus. AB - Selective removal of the envelope of equine abortion (herpes) virus was accomplished by utilizing the nonionic detergent Nonidet P-40 followed by sonic treatment. The deenveloped particles differ significantly in size and buoyant density from the enveloped form. The cellular entry of purified enveloped and purified deenveloped virus was examined by electron microscopy during critical time periods. Both forms appeared to enter cells by a viropexis mechanism in which particles were engulfed by pseudopodia which either surround the virus and fuse with the cell membrane or to other pseudopodia, forming fusion vacuoles containing from one to numerous viral particles. This mode of entry was noted extensively at 5 min postinoculation. Deenveloped particles were apparently infectious only for hamsters, with a large inoculum being required. Contamination by enveloped forms was not noted after exhaustive search by electron microscopy. PMID- 4195056 TI - [A statistical report of nine paraproteinemia cases]. PMID- 4195057 TI - [Fluctuation of immunoglobulin and antibacterial, antitoxic antibody responses in premature, newborn infants and young children. 1. Fluctuation of serum protein and immunoglobulin levels in premature, and newborn infants and young children]. PMID- 4195058 TI - Treatment of Gilbert's syndrome with phenobarbitone. PMID- 4195060 TI - Cancer prevention. PMID- 4195059 TI - Parathyroid hormone and experimental osteosclerosis. PMID- 4195061 TI - ABC of endocrinology. VI. The thyroid gland. PMID- 4195062 TI - Excess male false-positives among infants with phenylketonuria. PMID- 4195063 TI - Availability of candidates for consultant posts in chemical pathology. PMID- 4195065 TI - Prevention of leucocyte-antibody formation. PMID- 4195067 TI - Cataract surgery and intraocular implants. PMID- 4195066 TI - Reed-Sternberg-like cells in lymphocytic lymphoma and chronic lymphocytic leukaemia. PMID- 4195068 TI - Heterotopic ciliated epithelium--mullerian origin? PMID- 4195069 TI - Effect of corticotropin on plasma-growth-hormone. PMID- 4195070 TI - Growth hormone in acute myocardial infarction. PMID- 4195071 TI - Cytogenic analysis of cord-blood lymphocytes. PMID- 4195072 TI - Relationship of diabetic retinopathy to blood-sugar. PMID- 4195073 TI - The electrocardiogram in males with the 47,XYY karyotype. PMID- 4195074 TI - Orange soles. PMID- 4195075 TI - Orange soles. PMID- 4195076 TI - Myalgia and bird-keeping. PMID- 4195077 TI - House-dust, mites, and asthma. PMID- 4195078 TI - Repair of the perineum. PMID- 4195079 TI - Frederick Cecil Wray Capps, F.R.C.S. PMID- 4195080 TI - Kidney function after transplantation. PMID- 4195081 TI - Opening of the cardia. PMID- 4195082 TI - [Unconventional solution of the problems of parking and communication within the district Orrholmen, Karlstad]. PMID- 4195083 TI - Remarks on the nomenclature of cardiac arrhythmias. PMID- 4195084 TI - The electrocardiogram in complicated acute myocardial infarction. PMID- 4195085 TI - Primary and secondary male characteristics: the hairiness and large penis stereotypes. PMID- 4195086 TI - [Classification of chronic hepatitis with special reference to active or aggressive chronic hepatitis]. PMID- 4195087 TI - [Study of plasmas with reference to their selection for the preparation of anti Rh gamma globulins for the prevention of Rh iso-immunization]. PMID- 4195089 TI - [Changes in the blood and global hemostasis during recovery from acute histamine shock]. PMID- 4195088 TI - Pulmonary hyaline membranes in adults receiving oxygen therapy. PMID- 4195090 TI - [The behavior of immunoglobulins in multiple sclerosis]. PMID- 4195091 TI - Whipple's disease: newer concepts of therapy. PMID- 4195092 TI - Morphology of transmissible gastroenteritis virus of pigs. A possible member of coronaviruses. Brief report. PMID- 4195093 TI - Characteristics of transducing group A streptococcal bacteriophages A 5 and A 25. PMID- 4195094 TI - Comparative immunofluorescent studies on measles, canine distemper, and rinderpest viruses. Immunofluorescence of measles, distemper, and rinderpest viruses. PMID- 4195095 TI - [General lead intakes through foodstuffs and beverages]. PMID- 4195096 TI - Ultrastructural organization of spheroplasts induced in Mycobacterium sp. smegmatis by lysozyme or glycine. PMID- 4195098 TI - Compensatory hormonogenic hyperactivity of thyroid homo- and autografts, as well as of regenerates in situ, in the thyroidectomized guinea pig--comparative chemical and radiobiological study. PMID- 4195097 TI - [Pre- and post-operative functional and scintigraphic study in some surgical thyroid diseases]. PMID- 4195099 TI - [State of the chromosome apparatus of the bone marrow elements in healthy persons]. PMID- 4195100 TI - [Method of setting up hemocultures for chromosome analysis]. PMID- 4195101 TI - [Morphocytochemical characteristics of intravital liver puncture in cholecystopancreatitis]. PMID- 4195102 TI - [Cytochemical study of several enzymes in liver cells in children]. PMID- 4195103 TI - [Picture of the peripheral blood in patients with acute pneumonia during the period of the outbreak of influenza A2 (Hong Kong) 68 in January-March 1969]. PMID- 4195104 TI - [Method for obtaining chemical (acid) erythrograms]. PMID- 4195105 TI - [Clinico-laboratory diagnosis of various forms of porphyria and porphyrinuria]. PMID- 4195106 TI - [Spectrographic determination of several microelements in biological media]. PMID- 4195107 TI - [Experience in the use of analytic ultracentrifugation in clinical practice]. PMID- 4195108 TI - [Method of electrophoresis of breast milk proteins]. PMID- 4195109 TI - [Determination of blood sugar by the orthotoluidine method]. PMID- 4195111 TI - [Method of studying allergy in rheumatism]. PMID- 4195110 TI - [Transamidinase and its determination in clinical practice]. PMID- 4195112 TI - [An indicator of an allergic state (antihistaminic factor) in bronchial asthma]. PMID- 4195113 TI - [Methods of studying the microbial invasion of the pharynx, nose and mouth cavity in several respiratory infections (review of the literature)]. PMID- 4195114 TI - [Pipette for the automatic measuring of liquid volumes]. PMID- 4195115 TI - Effects of adhesive drapes on contamination of operation wounds. PMID- 4195116 TI - Intracranial-pressure changes following head injury. PMID- 4195117 TI - The fist as an external cardiac pacemaker. PMID- 4195118 TI - Comparison of fenfluramine and metformin in treatment of obesity. PMID- 4195119 TI - Discriminant function based on steroid abnormalities in patients with lung cancer. PMID- 4195120 TI - Sleep-walking in twins. PMID- 4195121 TI - Treatment of chronic hepatic encephalopathy. PMID- 4195122 TI - Dystrophia myotonica: identification of heterozygotes. PMID- 4195123 TI - A new line on age pigment? PMID- 4195124 TI - Selection of housemen. PMID- 4195125 TI - Finding the typhoid carrier. PMID- 4195126 TI - A living wage. PMID- 4195127 TI - Reserpine in Raynaud's phenomenon. PMID- 4195128 TI - One year's experience in a drug-dependence clinic. PMID- 4195129 TI - Appointment of provisionally registered house-officers by computer match. PMID- 4195130 TI - Continuity of clinical training. PMID- 4195132 TI - Sterilisation of women. PMID- 4195131 TI - Population policy. PMID- 4195133 TI - Immunological approach to ageing. PMID- 4195134 TI - Ketamine. PMID- 4195135 TI - Medical care in the United States. PMID- 4195136 TI - Variants of alpha-fetoprotein. PMID- 4195137 TI - Absence of alpha-1-fetoprotein antigen or antibody in maternal sera. PMID- 4195138 TI - Alpha 1-fetoprotein in Spain. PMID- 4195139 TI - Screening blood donors for Au antigen. PMID- 4195140 TI - Australia antigen and hepatitis. PMID- 4195141 TI - Phenobarbitone in intrahepatic biliary atresia. PMID- 4195142 TI - Battered babies. PMID- 4195143 TI - Free-radical damage in retrolental fibroplasia. PMID- 4195144 TI - Headache and the eye. PMID- 4195145 TI - Psychogeriatric assessment unit. PMID- 4195146 TI - L.A.T.S. and Graves' disease. PMID- 4195147 TI - Blood activity of 125-I-fibrinogen in venous thrombosis. PMID- 4195149 TI - L-dopa in progressive supranuclear palsy. PMID- 4195148 TI - Catecholamine metabolisn in sympathetic-tumour cells. PMID- 4195150 TI - Effects of withdrawing dopa in Parkinson's disease. PMID- 4195151 TI - An epidemic of dysentery in Nicaragua. PMID- 4195152 TI - Role of artificial lighting in decreasing the age of menarche. PMID- 4195153 TI - Growth hormone and diabetic angiopathy. PMID- 4195154 TI - Dialysis circuit monitors. PMID- 4195155 TI - Death attributed to kidney failure in communities with endemic urinary schistosomiasis. PMID- 4195156 TI - Systemic nocardiosis treated with trimethoprim and sulphamethoxazole. PMID- 4195157 TI - Detection of bacteriuria. PMID- 4195158 TI - Mycoplasma and the urogenital tract. PMID- 4195159 TI - Junior hospital staff in training. PMID- 4195160 TI - Against vagotomy. PMID- 4195161 TI - Direction for health service research. PMID- 4195163 TI - Digestion in the newborn. PMID- 4195162 TI - Familial metaphyseal dysplasia? PMID- 4195164 TI - ABO blood groups and Huntington's choera. PMID- 4195165 TI - [Pharmacologic mechanism of dimethyl sulfoxide (DMSO) based on cytological studies in cattle and clinical observations in sport horses]. PMID- 4195166 TI - [The prophylactic value of cattle gamma globulin in colisepsis of calves]. PMID- 4195167 TI - Molar absorbance coefficient of rhodopsin. PMID- 4195168 TI - Clinical value of liver function appraisal by means of 131-I-rose bengal. II. Comparison of the results of 131-I-rose bengal test with other biochemical tests. PMID- 4195169 TI - [The humanity of the human psychoanalytic aspects]. PMID- 4195170 TI - Biochemical abnormalities associated with turkey syndrome '65. PMID- 4195171 TI - Studies on the thyroid activity in the mouse. 2. The effects of stress and other changes in corticotrophin secretion. PMID- 4195172 TI - Immunologic and electron microscopic studies in Goodpasture's syndrome. PMID- 4195173 TI - Development and organization of periodontal membrane and physiologic tooth movement. PMID- 4195174 TI - [Diagnosis of the most important cardiac arrhythmias]. PMID- 4195175 TI - [Value of fluorescent microscopy for the detection of tubercle bacilli]. PMID- 4195176 TI - Interaction of antibiotics with deoxyribonucleic acid. I. Sensitivity of the complexes to nucleolytic enzymes. PMID- 4195177 TI - [The use of fluorescence examination in cytodiagnosis of an orbital neoplasm]. PMID- 4195179 TI - [Cell growth stimulating factors in patients with mononucleosis]. PMID- 4195178 TI - [Gastric acid secretion]. PMID- 4195180 TI - The spoken word: delivering a lecture, reading a paper, and giving a demonstration at congresses and meetings. PMID- 4195181 TI - [The banding of the pulmonary artery as a palliative treatment in the heart interventricular communication of the infant]. PMID- 4195182 TI - [Palliative surgery in transposition of great vessels]. PMID- 4195183 TI - [Hepatic satelite lesion in biliary calculi]. PMID- 4195184 TI - [Simple and reliable investigation: immediate examination of vaginal contents]. PMID- 4195185 TI - Immunological studies with papain and mexicain. II. PMID- 4195186 TI - [Determination of the height of amputation in arterial occlussive disease by intraoperative vital staining]. PMID- 4195187 TI - [Possibilities of a causative therapy of asthma in the child]. PMID- 4195188 TI - A unopette for eosinophil counts. PMID- 4195189 TI - A staining technic for differentiating yeast cells from squamous epithelial nuclei on clinical smears. PMID- 4195190 TI - [Ultrastructure of the carotid artery]. PMID- 4195191 TI - [Data on the mechanism of metachromasia of plant nucleolar RNA through the intermediary of uranyl ions]. PMID- 4195192 TI - Iodine and thyroxine metabolism in anephric patients receiving chronic peritoneal dialysis. PMID- 4195193 TI - Specific demonstration of the human hypophyseal cells which produce adrenocorticotropic hormone. PMID- 4195194 TI - Studies on tryptophan metabolism in male subjects treated with female sex hormones. PMID- 4195195 TI - Thyroglobulin and thyroid acid protease activity in thyroid disease. PMID- 4195196 TI - Thyroid function in euthyroid Jamaicans. PMID- 4195197 TI - Response to synthetic thyrotropin-releasing hormone in man. PMID- 4195198 TI - 9alpha-halogenated progestagens in the maintenance of pregnancy. PMID- 4195199 TI - An electron-microscope study of bacteria in two cases of Whipple's disease. PMID- 4195200 TI - The effect of dose level of intravaginal progestagen on sperm transport, fertilization and lambing in the cyclic Merino ewe. PMID- 4195201 TI - Severe myositis during recovery from influenza. PMID- 4195202 TI - Effect of age on calcium absorption. PMID- 4195203 TI - Failure of corticosteroid therapy to correct the hypercalcaemia of malignant disease. PMID- 4195204 TI - Presentation of cadaveric kidneys for transplantation. PMID- 4195205 TI - Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin. PMID- 4195206 TI - Serum-insulin or plasma-insulin? PMID- 4195207 TI - Gastric secretion in a healthy man, 1949-69. PMID- 4195209 TI - A waste-trap-sterilising method. PMID- 4195208 TI - Rapid correction of acidosis and dehydration of cholera with oral electrolyte and glucose solution. PMID- 4195210 TI - How many people? PMID- 4195211 TI - Recurrent bacteriuria. PMID- 4195212 TI - At what temperature should you keep a baby? PMID- 4195213 TI - Adding drugs to intravenous infusions. PMID- 4195214 TI - Left ventricular hypertrophy and ischaemic heart-disease. PMID- 4195215 TI - Biological age of man. PMID- 4195216 TI - Corticosteroids and corticotrophins. PMID- 4195217 TI - Prospects for social work in general practice. PMID- 4195218 TI - Contamination of meat carcasses by antibiotic-resistant coliform bacteria. PMID- 4195219 TI - What about the colleges? PMID- 4195220 TI - Combined treatment of parkinsonism with L-dopa and amantadine. PMID- 4195221 TI - Registrar General's supplement on abortion. PMID- 4195222 TI - Battered babies. PMID- 4195223 TI - Tests for syphilis in children for adoption. PMID- 4195224 TI - Ageing. PMID- 4195225 TI - Animal sources of Escherichia coli in food. PMID- 4195226 TI - Treatment of chronic moniliasis with lymphocyte transfusions. PMID- 4195227 TI - Ketamine and polyneuropathy. PMID- 4195228 TI - Precordial thumping. PMID- 4195229 TI - Gastrin secretion in the pancreas? PMID- 4195230 TI - Red-cell triosephosphate isomerase and chromosome 5. PMID- 4195231 TI - Diabetes and migraine. PMID- 4195232 TI - Painful deep-vein syndrome. PMID- 4195233 TI - Hyperparathyroidism in chronic renal failure. PMID- 4195234 TI - Role of artificial lighting in decreasing the age of menarche. PMID- 4195235 TI - Aetiology of Crohn's disease. PMID- 4195236 TI - B.C.G. treatment in Crohn's disease. PMID- 4195237 TI - Control of tuberculosis. PMID- 4195238 TI - Syndrome of the sea-blue histiocyte. PMID- 4195239 TI - Infectious hepatitis and Down's syndrome. PMID- 4195240 TI - Medical care in the United States. PMID- 4195241 TI - Control of lymphocyte level in the blood. PMID- 4195242 TI - Effect of psychotomimetic agents on sex ratio? PMID- 4195243 TI - Regular haemodialysis and renal transplantation. PMID- 4195245 TI - Occult blood. PMID- 4195244 TI - Platelet adhesiveness in Hageman trait. PMID- 4195246 TI - Milk-bottle problem. PMID- 4195247 TI - Design of skin flaps. PMID- 4195248 TI - Severe hypoglycaemia after glibenclamide. PMID- 4195249 TI - Robert Francis Jack Henry, M.B. Dubl., F.R.C.S.I. PMID- 4195251 TI - Learning carrels in a clinical course. PMID- 4195250 TI - Automatic hand viewers and cassette play-back units. PMID- 4195252 TI - Individualized instruction for the college curriculum. PMID- 4195253 TI - [Effect of betaine citrate on liver metabolism and regeneration after partial hepatectomy in rats]. PMID- 4195254 TI - Diffuse cutaneous leishmaniasis in Ethiopia. 3. Immunological studies. IV. Pathogenesis of diffuse cutaneous leishmaniasis. PMID- 4195255 TI - [Orthopedic experiences with Celestan-Depot and the combination of betamethasone and phenylbutazone (Celestalgon)]. PMID- 4195256 TI - [Myopathy syndrome in hyperthyroidism]. PMID- 4195257 TI - [New aspects of hematologic and parasitologic diagnosis using fluorescent microscopy]. PMID- 4195258 TI - [Dependence of the penetration velocity of Neutral Red into cells on sorption ability of its diffusion barriers]. PMID- 4195260 TI - [Papillary drusen with a tumoral aspect]. PMID- 4195259 TI - [Cyto-hormonal control of pregnancy. A rapid staining method for vaginal smears]. PMID- 4195261 TI - [Gestagen therapy of endometrial neoplasms]. PMID- 4195262 TI - [Influencing the term in hogs using gestational hormones]. PMID- 4195263 TI - [Streptomycin therapy in pigeons]. PMID- 4195264 TI - [The serum lysozyme in chronic myeloleukosis]. PMID- 4195265 TI - [Familial reticuloendotheliosis in early infancy]. PMID- 4195266 TI - [New studies in the field of Cooley's anemia]. PMID- 4195267 TI - [Cytochemical studies on blood cells in comparative hematology]. PMID- 4195268 TI - [Cytochemical studies on leukocytes in various domestic and laboratory animals]. PMID- 4195269 TI - [Organ changes in healthy rabbits following long-term myelobromol treatments]. PMID- 4195270 TI - Remarks to the haemogram of the pheasants. PMID- 4195271 TI - [Short-term changes of the hemogram in the doe and pheasant following injection of chlorprothixene]. PMID- 4195272 TI - [Phylogenesis of serum proteins, especially of immunoglobulins]. PMID- 4195273 TI - [The pylogenesis of hemostasis]. PMID- 4195274 TI - [Clinical studies in therapy using coagulation-active plasma concentrates]. PMID- 4195275 TI - [Experiences in the preparation and analytical control of Cohn's plasma fraction I]. PMID- 4195276 TI - [Further experimental studies on preparations following a modified method of factor VIII (AHG) isolation by freeze precipitation. II]. PMID- 4195277 TI - [Plasmapheresis for the isolation of coagulating plasma fractions]. PMID- 4195278 TI - [Isolation of the PPSB fraction in a blood bank]. PMID- 4195279 TI - [A human plasma fraction (PPSB) enriched with the coagulation factors II, VII, IX and X]. PMID- 4195280 TI - [In-vivo control of blood coagulation fractions]. PMID- 4195281 TI - [Experiences in the use of Cohn's fraction I]. PMID- 4195282 TI - [Long-term treatment of hemophilia A with plasma fractions]. PMID- 4195283 TI - [The dosage of antihemophilic globulin, or antihemophilic plasma as well as Cohn's fraction I in factor VIII deficiency]. PMID- 4195284 TI - [The use of human gamma globulin in antibiotic resistant pyogenic cases]. PMID- 4195285 TI - [Standardization of the thromboplastin generation test for the determination of antihemophilic globulin A (VIII) and B (IX)]. PMID- 4195286 TI - [Multiple accidental carbon monoxide poisoning during sex relations in a parked car in a garage]. PMID- 4195287 TI - [The value of direct examination of grains in the diagnosis of mycotomas. A new technic of investigation]. PMID- 4195288 TI - [Clinical picture of the pseudo papilledema caused by drusen deposits]. PMID- 4195289 TI - [Morphological methods in the evaluation of contrast media used in cerebral arteriography]. PMID- 4195290 TI - [A comparative study of human allergic antibodies in the Prausnitz-Kuestner test and the passive sensitization test of human isolated smooth muscle organs]. PMID- 4195291 TI - [Long-term prognosis of the neuropsychological development of premature children]. PMID- 4195292 TI - [Autoimmune disease]. PMID- 4195293 TI - [2 cases of myeloma with paraprotein of alpha 2 motility]. PMID- 4195294 TI - [Trans-sacrum anesthesic block in bladder pain]. PMID- 4195295 TI - [Antibodies for formed blood elements and immunoglobulins in chronic liver diseases]. PMID- 4195296 TI - [Scabies. Guiding symptom: pruritus]. PMID- 4195297 TI - [Effect of 3-amino-1,2,4-triazole (amitrol) on the ultrastructure of Azotobacter]. PMID- 4195298 TI - Effect of macrophage engulfment and temperature on the transformation process of Leishmania donovani. PMID- 4195299 TI - The fine structure of human somatic chromosomes studied by scanning electron microscopy and the replica method. PMID- 4195300 TI - Inactivation of "Arvin" by plasma proteins. PMID- 4195301 TI - [Insufficiency of alizarin staining in the study of osteogenesis of the maxilla in man]. PMID- 4195302 TI - Studies on comparison of staining of Treponema pallidum with that of Borrelia recurrentis as seen from long-term preservation of the specimen. I. Positive staining. PMID- 4195303 TI - A contribution to staining of Treponema pallidum in tissue. I. Staining of Treponema pallidum in tissue using silver staining solution with surface-active agents. PMID- 4195304 TI - A contribution to staining of Treponema pallidum in tissue. II. Concentration of silver nitrate solution suitable for staining of Treponema pallidum in tissue. PMID- 4195305 TI - Fluorescence in skin cancer showing verruca senilis in appearance. PMID- 4195306 TI - A contribution to staining of Treponema pallidum in tissue. 3. An evaluation of surface-active agents for staining of Treponema pallidum in tissue. PMID- 4195307 TI - Application of fluorescent dyes to dermatological investigation. V. Fluorescent microscopial study of squamous cell carcinoma. PMID- 4195308 TI - A contribution to staining of Treponema pallidum in tissue. IV. Staining of Treponema pallidum in tissue of syphilid in test-rabbit and man. PMID- 4195309 TI - Application of fluorescent dyes to dermatological investigation. VI. Fluorescent microscopical study of precancerous state and basal cell carcinoma. PMID- 4195310 TI - Symbolic interaction: analysis of listening. PMID- 4195311 TI - [Keratoconus and blue sclera in a congenital anomaly of connective tissue]. PMID- 4195312 TI - [The role of nucleic acids in immunogenesis]. PMID- 4195313 TI - [Structure of immunoglobulins]. PMID- 4195314 TI - [Partial reversible changes of various pathological phenomena by therapy at the molecular level. Chemical and experimental study and methods used in rabbits. I]. PMID- 4195315 TI - Comparison of video-tape and face-to-face interviewing. PMID- 4195316 TI - [The behavior of immunoglobulins during acute icterogenic hepatitis]. PMID- 4195317 TI - [Anti-DNA factors. Their diagnostic and prognostic importance in diffuse lupus erythematosus]. PMID- 4195318 TI - Computerized data analysis of hemodialyzers by a standard protocol shows true effective membrane area. PMID- 4195319 TI - Multiple antibody response following busulfan therapy. PMID- 4195320 TI - [Recent studies on antinuclear factors with special reference to differential diagnostic and genetic viewpoints]. PMID- 4195321 TI - [Serum lipids and serum proteins in old age]. PMID- 4195322 TI - [Immunological activity of residues from penicillin fermentation media and their significance for penicillin allergies]. PMID- 4195323 TI - [The binding of cephalosporin-C-antibiotics to proteins]. PMID- 4195324 TI - [Species specificity of the human gastric mucosa esterase VI A. I. Comparative studies on gastric mucosa extracts of rabbit, guinea pig, rat and men]. PMID- 4195325 TI - Desmosomes and hemidesmosomes in the flagellate Crithidia fasciculata. PMID- 4195326 TI - Ultrastructural studies of spontaneous spermiation in the guinea pig. PMID- 4195327 TI - Fine structure of pars neuro-intermedia of the loach, Misgurnus fossilis L. PMID- 4195328 TI - Fine structure of the vessels of the hypophysial portal system of the white crowned sparrow, Zonotrichia leucophrys gambelii. PMID- 4195329 TI - [Further investigations of hypophysial portal vessels of Zonotrichia leucophrys gambelii]. PMID- 4195330 TI - I-125 labelled thyroid hormones in cultured mammalian nerve tissue. PMID- 4195331 TI - [Studies on the ultrastructure of invertebrate hemocytes. II. On the hemocytes of Golfingia gouldi (Sipunculidae)]. PMID- 4195332 TI - [Fine structure of the kidney of the three-spined-stickleback (Gasterosteus aculeatus L.) during its mucous transformation]. PMID- 4195333 TI - [Embryonic origin and secretory differentiation of calcitonin cells (C cells) in the fetal rat thyroid. Electron microscopic study]. PMID- 4195334 TI - On surgical treatment of prostatic hyperplasia. PMID- 4195335 TI - Malaria: host-defense mechanisms and complications. PMID- 4195336 TI - Methodological observations on the histochemical demonstration of glycogen phosphorylase activity. PMID- 4195337 TI - The bile canaliculi in experimental liver disorders. A cytochemical study in guinea pigs. PMID- 4195338 TI - Effect of anaesthesia on the behaviour of exogenous 5HT in area postrema of rat and mouse brain studies by fluorescence microscopy. PMID- 4195339 TI - [The occurrence of helical arranged ribosomes of Rhodopseudomonas palustris]. PMID- 4195340 TI - Sarcoidosis with atrophic lesions and ulcers and the presence in some sarcoid granulomata of orceinophil fibres. PMID- 4195341 TI - An unusual variant of lupus erythematosus or lichen planus. PMID- 4195342 TI - The cell surface coat of normal keratinocytes and of acantholytic keratinocytes in pemphigus. An electron microscopic study. PMID- 4195343 TI - Symbolism in the treatment of schizophrenia. PMID- 4195344 TI - Human fascioliasis in Shropshire. AB - Five patients with fascioliasis presented with malaise, pruritus, and pain in the right hypochondrium. Eosinophilia, increase in serum gamma globulin, and pyrexia were other features. Four patients treated with oral bithionol recovered completely and it is suggested that this is an effective form of therapy. The double diffusion precipitin test, being speedy and simple, was used as a screening procedure for diagnosis. The source of infection was wild watercress growing in a farm ditch. PMID- 4195345 TI - Propranolol and serum calcium in thyrotoxicosis. PMID- 4195347 TI - [Apropos of the debate on the technics of adenomectomy]. PMID- 4195346 TI - A controlled trial of three regimens of self-administered and supervised chemotherapy for pulmonary tuberculosis. A. General report. PMID- 4195348 TI - [Hemostasis and treatment of the prostatic niche after transvesical adenomectomy]. PMID- 4195349 TI - [Our experience with prostatic adenomectomy]. PMID- 4195351 TI - [Anesthesia-resuscitation in interventions for prostatic adenoma]. PMID- 4195350 TI - [Prostatic surgery. Diverse interventions]. PMID- 4195353 TI - [Prostatic adenomectomy according to the Hryntschak technic]. PMID- 4195354 TI - [Refsum's disease]. PMID- 4195355 TI - [Situation concerning developmental deviation in a child: physician-parent contacts]. PMID- 4195356 TI - [Disopyramide (Rhythmodan) in disorders of ventricular excitability]. PMID- 4195357 TI - [Therapy of leukopenias. Pharmacological and toxicological findings on a thymus extract]. PMID- 4195358 TI - Emetine myopathy. PMID- 4195359 TI - Antineuronal antibodies in patients having myasthenia gravis. PMID- 4195360 TI - Investigation of the symbolic self using the concentric circles method and animal metaphor. PMID- 4195361 TI - Authoritarianism among white and black deaf adolescents: two measures compared. PMID- 4195362 TI - [The cells of the adenohypothysis and the problem of localizing the biosynthesis of corticotropin]. PMID- 4195363 TI - [The luminescent-morphologic method of demonstrating globulins in the affected skin of patients with erythrodermia and discoid lupus erythematosis]. PMID- 4195364 TI - [The mode of discharge of zoosporangia in Saprolegnia monoica (Pringsheim DeBary)]. PMID- 4195365 TI - [Purified phage receptors from Proteus mirabilis VI culture filtrates]. PMID- 4195366 TI - [Light and electron microscopic studies of the effect of Labyrinthula enzyme on bacterial and yeast cells]. PMID- 4195367 TI - [Studies of the importance of chrondroids (mesosomes) for bacteria cells by means of statistical evaluation of electron microscopic images]. PMID- 4195368 TI - [Clinical and blood chemical analytical studies in osteogenesis imperfecta]. PMID- 4195369 TI - [Rapid diagnosis of influenza by the method of indirect fluorescence staining]. PMID- 4195370 TI - [DNA metabolism and antibody production after application of different antigens]. PMID- 4195371 TI - [The bacteriological diagnosis of Vibrio El Tor infection]. PMID- 4195372 TI - Biosynthesis of gramicidin S. PMID- 4195373 TI - Electron microscopy of enzymes. PMID- 4195374 TI - Clinicopathologic study of 53 cases of Brenner's tumors of the ovary. PMID- 4195375 TI - Morphology of alveolar lining layer. PMID- 4195376 TI - The cell population in pancreatic islets of Amphisbaenidae--a light and electron microscopic study. PMID- 4195377 TI - A histochemical and fine structural study of early extracellular connective tissue in the chick embryo. PMID- 4195378 TI - Fine structural study of rat molar cementum. PMID- 4195379 TI - Brunner's glands of the echidna. PMID- 4195380 TI - [An unusually broad type of fimbria]. PMID- 4195381 TI - Advances in asthma. Hypersensitivity mechanisms. PMID- 4195382 TI - [Gomori- and Sterba-positive substance observed in the subcommissural organ during the ontogeny of chicks]. PMID- 4195383 TI - [Changes in the nucleoli in the fibers of rat hypertrophied myocardium during blockage of the synthesis of RNA]. PMID- 4195384 TI - [Synthesis of protein in the embryonic development of the sea urchin following nuclei inactivation]. PMID- 4195385 TI - Immunospecificity of fluorescein-conjugated anti-human beta 1C-globulin method for detection of cell-bound antibody. PMID- 4195386 TI - Specific inhibition of acid phosphatase-3 in pollen of maize by the diazonium salt fast garnet GBC. PMID- 4195387 TI - Histochemical azo coupling reactions of the pigments of obstructive icterus and of hematoidin. I. Diazonium salts used. PMID- 4195388 TI - Exogenous cytochrome c as an ultrastructural tracer. PMID- 4195389 TI - Fluorescent nuclear staining with europium thenolytrifluoroacetonate. PMID- 4195390 TI - An introduction to electrocardiography by an automatic audio-visual technique. PMID- 4195391 TI - [Immunofluorescent study on localization of immunoglobulins in the mucous membrane in chronic maxillary sinusitis]. PMID- 4195392 TI - [Comparative study of argentic staining technic in the impregnation of Paramaecium aurelia]. PMID- 4195393 TI - [Current status of the epidemiology and prophylaxis of post-transfusional hepatitis]. PMID- 4195394 TI - Measles (rubeola) in previously immunized children. PMID- 4195395 TI - Am(1), the first genetic marker of human immunoglobulin A. AB - The genetic markers of human immunoglobulins have significantly contributed to the understanding of the molecular biology of antibody synthesis. Like the Gm markers of IgG, the first genetic marker of serum IgA, a major immunoglubulin of exocrine secretions, has now been defined and termed Am(1). It is inherited as a Mendelian dominant trait and is independent of the Gm and Inv allotypes. Am(1) is localized in the alpha-chains of the gammaA(2) subclass and is independent of the serum gammaA(2) levels. Its polymorphism makes it suitable for studies in population genetics and the molecular biology of IgA globulin. PMID- 4195397 TI - [The C.S.F. protein formula in central nervous system diseases and especially in multiple sclerosis. Study of 218 examinations]. PMID- 4195396 TI - Properties of halves of immunoglobulin light chains. AB - Light polypeptide chains from both normal human gammaG immunoglobulin and Bence Jones proteins can be cleaved into halves by limited proteolysis with trypsin, pepsin, or papain. The fragments were obtained in yields of up to 22 per cent, had molecular weights of 10,000 to 11,000, and were shown by amino acid analysis and antigenic analysis to correspond to variable or constant regions of light chains. Starch gel electrophoresis in urea suggested that each half consisted of a single polypeptide chain. A fragment from the urine of a myeloma patient corresponded almost exactly to the constant half of a gamma-chain and had a compact shape (Stokes radius of 16 A; frictional ratio of 1.1). Similar Stokes radii were estimated both on fragments from normal urine and fragments produced by proteolysis of normal light chains. The results are consistent with the view that most urinary fragments have a catabolic origin and suggest that there is a small stretch of polypeptide chain between the compact V and C regions of light chains which is particularly susceptible to proteolysis. This lends support to the hypothesis that immunoglobulin chains consist of globular domains connected by more extended stretches of polypeptide chain. PMID- 4195398 TI - Allergic protein-losing gastroenteropathy: report of an unusual case. PMID- 4195399 TI - [Comparison of an agent of a communicable disease of monkeys with a vesicular stomatitis virus. II]. PMID- 4195401 TI - Intracellular staining of physiologically identified interneurones in the cat spinal cord. PMID- 4195400 TI - [Fluorochromization of human chromosome plates by means of the Feulgen fluorescent reaction]. PMID- 4195402 TI - Suppurative parotitis in children. PMID- 4195403 TI - Sudden unexpected death (SUD). PMID- 4195404 TI - The effects of d-tubocurarine on spontaneous postganglionic sympathetic activity and histamine release. PMID- 4195405 TI - [Advantage of the use of an estroprogestational drug: 3 mg of chlormadinone acetate + 100 mcg of mestranol in endocrine gynecology]. PMID- 4195406 TI - [Protein-bound iodine of the blood]. PMID- 4195407 TI - [Prophylaxis of rhesus iso-immunization by anti-D immunoglobulin]. PMID- 4195408 TI - [Possible interferences of thyrocalcitonin with thyroid activity. I. Study with the use of extractive thyrocalcitonin]. PMID- 4195409 TI - Dual staining of some sulfated mucopolysaccharides with alcian blue (pH 1.0) and ruthenium red (pH 2.5). PMID- 4195410 TI - A simplified benzoylation-diazonium coupling sequence for demonstrating conjugated proteins. PMID- 4195411 TI - [Vaccinia immune globulin]. PMID- 4195412 TI - [Study of the rheumatoid factor in aged subjects]. PMID- 4195413 TI - [Production of anti-tetanic human gammaglobulins with the aid of a vaccine adsorbed on calcium phosphate]. PMID- 4195414 TI - [Prostatectomy--our hemostatic method]. PMID- 4195415 TI - [Combined ovariectomy and adrenalectomy in the therapy of advanced breast carcinoma]. PMID- 4195416 TI - [Regional hyperoxygenation: an important factor in the potentiation of antineoplastic chemotherapy]. PMID- 4195417 TI - [Methods of hormonal iodine determination in blood]. PMID- 4195418 TI - [Radio-iodine metabolism]. PMID- 4195419 TI - [Comparative studies of experimental pathogenesis of herpes simplex virus in mice. Intracerebral, Intraperitoneal and oral infection of the suckling mice]. PMID- 4195420 TI - Effects of low concentrations of thyroid stimulating hormone: pharmacological experiments in vitro. PMID- 4195421 TI - Treatment of toxic nodular and diffuse goitre with radioactive iodine. Late results and use of carbimazole. PMID- 4195422 TI - Effects of continuous daily administration of 0.3 mg of norehtindrone on the plasma levels of progesterone and on the urinary excretion of pregnanediol and total oestrogens. PMID- 4195423 TI - Demonstration of splenic metallophilic cells in bacterial infectious disease. PMID- 4195424 TI - Experimental amyloidosis induced by immune complex or heat denatur ed DNA. I. An electron microscopic observation. PMID- 4195425 TI - Selective injury of mitochondria with Janus green B and ruby laser light--enzyme morphological and ultrastructural study. PMID- 4195426 TI - Interaction, a teaching tool in chemistry education. PMID- 4195427 TI - [Cutaneous thesaurismosis caused by polyvinylpyrrolidone (Dupont and Lachapelle disease). 3 new cases]. PMID- 4195428 TI - [Changes in plasma transport of T4 during pharmacological treatment]. PMID- 4195429 TI - [Study of plasma transport and metabolism of thyroid hormones in diabetes mellitus and various metabolic diseases]. PMID- 4195430 TI - [Physiopathology of plasma beta-globulin binding 17-beta-hydroxysteroids]. PMID- 4195431 TI - [Rhythm and conduction disorders and amyloidosis. An anatomo-clinical case]. PMID- 4195432 TI - Simplified method for estimation of serum and plasma viscosity in multiple myeloma and related disorders. PMID- 4195433 TI - [Isolation and characterization of antibodies from human sera infected with Echinococcus granulosus]. PMID- 4195434 TI - [Experiences in smallpox vaccination of children with endogenous eczema]. PMID- 4195435 TI - [Thyroid hormone binding proteins in human sera]. PMID- 4195436 TI - [Hydrocephalus]. PMID- 4195437 TI - [Liberation of vasoactive substances in experimental acute hemorrhagic pancreatitis in dogs]. PMID- 4195438 TI - [Fibrinolytics. 46]. PMID- 4195439 TI - Albumin and IgG turnover studies in patients with cirrhosis. PMID- 4195440 TI - Immunoglobulin M (IgM) turnover in hepatitis. PMID- 4195441 TI - The effects of azathioprin in patients with cirrhosis of the liver. PMID- 4195442 TI - Alcoholic hepatitis in the spectrum of ethanol-induced liver injury. PMID- 4195443 TI - [Sero-epidemiological study of resistance to beta-mercaptoethanol in sera with poliomyelitis antibodies]. PMID- 4195444 TI - [Localization of the specific neutralizing activity in poliomyelitis antibodies treated with papain, pepsin and reducing agents]. PMID- 4195445 TI - [Generalized zoster in lymphatic leukemia]. PMID- 4195446 TI - [Histological investigations on guinea pigs (typhoid bacteria excretors) experimentally infected with Salmonella typhi]. PMID- 4195447 TI - Modeling and transfer of composed bone autograft in tubed flap--in experiment. PMID- 4195448 TI - Neurofibromatosis of the head. PMID- 4195449 TI - New method of plastic operation of pharyngoesophageal tract in case of extensive laryngectomy because of cancer. PMID- 4195450 TI - The task of sex and age in formation of Dupuytren's contracture. PMID- 4195451 TI - Contribution to the research of malformations on the hands. PMID- 4195452 TI - Results of tubed pedicle flap plasty in large and complicated eyelid defects. PMID- 4195453 TI - Transplantation of homologous cartilage sterilized in formalin vapours. (Preliminary report). PMID- 4195454 TI - In memoriam Frantisek Burian, the founder of the Czechoslovak plastic and reconstructive surgery. PMID- 4195455 TI - Histamine release inhibition in anti-inflammatory mechanism. PMID- 4195456 TI - Binding of photosensitizing dyes with some biopolymers. PMID- 4195457 TI - Diagnosis of beta thalassaemia in the newborn by means of haemoglobin synthesis. PMID- 4195458 TI - Ultrastructure and distribution of neuronal and glial elements on the motoneuron surface in the lumbosacral spinal cord of the adult cat. PMID- 4195459 TI - Fetoprotein and albumin levels in the blood serum of developing neonatal pigs. PMID- 4195460 TI - Comparative circular dichroism studies of individual eel and human antibodies. PMID- 4195461 TI - Immunoglobulin formation and function in different tissues. PMID- 4195462 TI - Rheumatoid-factor-like substance and antistreptolysin O antibody in leprosy serum. Significance in erythema nodosum leprosum. PMID- 4195463 TI - Leprosy. II. IgA and IgM immunoproteins in leprosy sera. PMID- 4195465 TI - Special aids for the 1971 National Children's Dental Health Week. Bureau of Dental Health Education. PMID- 4195464 TI - Leprosy. 3. A comparison of IgA and IgM immunoproteins of patients with pulmonary tuberculosis and leprosy. PMID- 4195466 TI - Perfusion of the superior cervical ganglion of the cat with anti-permeable substance. PMID- 4195467 TI - The assessment of thyroid function by in-vitro techniques. A comparison of commercial kits. PMID- 4195468 TI - The bile canaliculi in cytological aspiration biopsies from patients with liver disorders. PMID- 4195469 TI - [Study of the influence of thymus extracts on the immunological response in experimental influenza. II. Studies of the action of some thymus extracts in influenza immunization]. PMID- 4195470 TI - [Some data on immunofluorescence]. PMID- 4195471 TI - [New classes of immunoglobulins in rabbit lacrimal secretion and bile]. PMID- 4195472 TI - [Comparative study of the superficial and periventricular limiting zones of the brain]. PMID- 4195474 TI - Method for permanent in situ display of retinal nerve fiber layer anatomy. PMID- 4195475 TI - Acute schistosomiasis Mansoni in 10 boys. An outbreak in Caguas, Puerto Rico. PMID- 4195476 TI - Thyrotoxicosis presenting as choreoathetosis. PMID- 4195473 TI - Infiltrative diseases of the small bowel and malabsorption. PMID- 4195478 TI - Nuclear distribution in the mycelium of Claviceps and the problem of strain selection. AB - Cytological studies of the developing mycelium of Claviceps suggest that genetic uniformity may be obtained in strains derived from single spores. PMID- 4195477 TI - Cytochemical electron microscopic localization o esterase activity in Lactobacillus casei. AB - Enzymes capable of hydrolyzing thiolacetic acid in two strains of Lactobacillus casei were localized by the formation of electron-opaque PbS deposits in vivo in the presence of Pb(NO(3))(2). By electron microscopy, the deposition of PbS appeared primarily at the plasma membrane and at the outer surface of the cell wall. PMID- 4195479 TI - Volutin granules in Zoogloea ramigera. AB - Zoogloea ramigera, a gram-negative bacterium found in activated sludge, formed volutin granules when excess orthophosphate was added to a phosphate-starved culture. These volutin granules were stainable by hydrogen sulfide after lead acetate treatment and extractable by N-perchloric acid but were not adsorbed by activated charcoal. They appeared to consist of inorganic polyphosphate. Optimum granule formation in the arginine broth required 10 g of glucose, 3 mg of phosphate, and 1 to 20 mg of magnesium per liter of medium. At an Mg(2+) concentration of 1 mg/liter, very large granules appeared which often appeared to fill the cell. An excess of glucose, orthophosphate, or magnesium reduced granule formation. In the absence of sulfate, moderate granulation occurred in arginine broth before the addition of excess orthophosphate; granulation did not increase after the addition of phosphate. PMID- 4195480 TI - Application of freeze-etching method to the study of reovirus-infected LLC-MK2 cells. AB - A continuous cell line of rhesus monkey kidney cells, LLC-MK(2), was infected with reovirus type 1 (Lang). The cells were freeze-etched as a method for observing the structural details of the reovirus-induced cytoplasmic inclusion. Information on maturation may be obtained by preparing infected cells for electron microscopy by freeze-etching. PMID- 4195481 TI - Lanthanum staining of Langerhans' cell. Communication of Langerhans' cell granules with extracellular space. PMID- 4195482 TI - Formalin pigment in skin. PMID- 4195483 TI - Macromolecular assemblies of lipid in bile. PMID- 4195484 TI - Immunofluorescent localization of mammary tumor virus antigens in mammary tumor cells in culture. PMID- 4195485 TI - [Distribution of Gomori-positive neurosecretion in the hypothalamo-hypophyseal system of Gobius melanostomus Pallas]. PMID- 4195486 TI - Localization of two species specific antigenic determinants on the peptide chains of calf skin collagen. PMID- 4195487 TI - [Polycythemia vera]. PMID- 4195488 TI - Role of erythrocyte destruction products in the mechanism of erythropoiesis autoregulation. PMID- 4195489 TI - [Cytology of experimental inflammations in childhood leukemia]. PMID- 4195490 TI - [Anaphylactic bone marrow crisis following isoniazid therapy]. PMID- 4195491 TI - [Cytostatic therapy causing the loss of serological activity in thrombocytes]. PMID- 4195492 TI - [Effect of intralipid on platelet adhesiveness]. PMID- 4195493 TI - [Blood coagulation in psychotic patients under the effect of electroshock]. PMID- 4195494 TI - [Tests on blood stains and human excreta by means of the group lectin anti-B1 (Euonymus alata)]. PMID- 4195495 TI - Antigenicity of polypeptides (poly alpha amino acids): calcium-dependent and independent antibodies. PMID- 4195496 TI - Delayed hypersensitivity to insulin and its component polypeptide chains. PMID- 4195497 TI - Independence of allotypic determinants and antibody specificity. PMID- 4195498 TI - Quantitation of canine immunoglobulins. PMID- 4195499 TI - The evolution of the immune response. VII. Antibody to human "O" cells and properties of the immunoglobulin in lamprey. PMID- 4195500 TI - Structural studies of immunoglobulin E. II. Amino terminal sequence of the heavy chain. PMID- 4195501 TI - Measurement of IgA levels in human cord serum by a new radioimmunoassay. PMID- 4195502 TI - [Some physico-chemical, immunochemical and immunoserological data on cryoprecipitable proteins in the course of chronic liver diseases]. PMID- 4195503 TI - [Latex-gammaglobulin reaction. Micromethod using shallow dishes with beakers]. PMID- 4195504 TI - Senate wins clean car race. PMID- 4195505 TI - Iodination and the biological activity of gastrin. PMID- 4195506 TI - Anthropological significance of gamma globulin (Gm and Inv) antigens in Bougainville Island, Melanesia. PMID- 4195507 TI - Mixed lymphocyte cultures and HL-A identity in unrelated subjects. PMID- 4195508 TI - In vitro sensitization of mouse peritoneal mast cells with reaginic antibody. PMID- 4195509 TI - [Recent data on monoclonal immunoglobulins]. PMID- 4195510 TI - [Cryptogenetic hypogammaglobulinemia and genetic determinism of some so-called acquired hypogammaglobulinemias]. PMID- 4195511 TI - [Modifications of the allotypic expression of immunoglobulins during some hemopathies]. PMID- 4195512 TI - Conservative management of genial tubercle fractures. PMID- 4195513 TI - A phantom head for teaching dental radiography. PMID- 4195514 TI - Bubble chamber pictures as a means of demonstrating radiation distribution in biological systems. PMID- 4195515 TI - [Adrenergic innervation of the cerebral vessels]. PMID- 4195516 TI - [Excretion of hexachlorane and its determination by the gas chromatography method]. PMID- 4195517 TI - Silver staining of micro- and oligodendroglia by means of physical development. PMID- 4195518 TI - Silver staining of fibrous neuroglia by means of physical development. PMID- 4195519 TI - Morphological studies of the neural spread of herpes simplex virus to the central nervous system. PMID- 4195520 TI - Comparison of various drug regimens in domiciliary chemotherapy. PMID- 4195521 TI - Pneumocystis carinii infection. A cytologic, histologic, and electron microscopic study of the organism. PMID- 4195522 TI - Histochemical staining of normal and Mycoplasma-infected turkey sinus epithelial cells. PMID- 4195523 TI - Renal transplantation: present status. PMID- 4195524 TI - [Monoclonal gammopathies]. PMID- 4195525 TI - [Immunoglobulins and paraproteins]. PMID- 4195526 TI - The effect of the carrier protein on the immune response and on the induction of tolerance in mice to the 2,4-dinitrophenyl determinant. PMID- 4195527 TI - Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti guinea-pig thyroglobulin serum. I. Light microscopic study. PMID- 4195528 TI - Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti guinea-pig thyroglobulin serum. II. Studies with fluorescent antibody technique. PMID- 4195529 TI - Antibody production in vitro. The effects of anti-allotypic serum on the secondary response of rabbit spleen cell suspensions to sheep erythrocytes (SRC). PMID- 4195530 TI - The recovery of immunological reactivity to some synthetic polypeptides containing proline after the induction of specific immunological tolerance. PMID- 4195532 TI - Studies on intravitreal initiation of the immune response. PMID- 4195531 TI - Auto-allergic reactions following internal irradiation of the liver. PMID- 4195533 TI - The symbolic attitude in psychotherapy. PMID- 4195534 TI - The archetypes in Peter Pan. PMID- 4195535 TI - Prenatal observations on the incisive fissure and the frontal process in man. PMID- 4195536 TI - Changing morphology of the uterine tubes of the domestic pig (Sus scrofa domesticus) with age. PMID- 4195537 TI - The acid-base surface: a three-dimensional visual model for analysis of acid-base information. PMID- 4195538 TI - Non-production of interfering substances by serum from patients with infectious hepatitis. PMID- 4195539 TI - The significance of intermediate fibres in reinnervated human skeletal muscle. PMID- 4195540 TI - Ultrastructural and histochemical correlations of experimental muscle regeneration. PMID- 4195541 TI - Effects of maternal dietary lipotropes on prenatal and neonatal rats. PMID- 4195542 TI - Care and management of a chimpanzee after cross-circulation with a hepatitis patient. PMID- 4195543 TI - Detection of a new serum-antigen in three epidemics of short-incubation hepatitis. PMID- 4195544 TI - HL-A matching in treatment of burned patients with skin allografts. PMID- 4195545 TI - Central venous pressure in clinical management of acute gastrointestinal bleeding. PMID- 4195546 TI - Stimulation of pancreatic secretion by intraduodenal infusion of bile-salts. PMID- 4195547 TI - Hypokalaemia in megaloblastic anaemias. PMID- 4195548 TI - Amitriptyline and cardiac disease. Risk of sudden death identified by monitoring system. PMID- 4195549 TI - Short-term anaphylactic IgG antibodies in human sera. PMID- 4195550 TI - Leucocyte antigens and placental sponge. PMID- 4195551 TI - The at-risk register. PMID- 4195552 TI - Lymphoid stimulation and lymphoid neoplasia. PMID- 4195553 TI - Urinary oestrogens in pill-users may be artefacts. PMID- 4195554 TI - Amyloidosis of Alzheimer's disease: a clue to ageing? PMID- 4195555 TI - Compartmentalisation of ascitic fluid. PMID- 4195556 TI - Neuromuscular disorders in rheumatoid arthritis. PMID- 4195557 TI - Cutting the cost of health care. PMID- 4195558 TI - Coordinated care of the child with spina bifida. PMID- 4195559 TI - Emergency call service. PMID- 4195560 TI - Epidemic Shiga dysentery in Central America. PMID- 4195562 TI - Sterilisation of women. PMID- 4195561 TI - Population policy. PMID- 4195563 TI - Sterilisation of women. PMID- 4195564 TI - Royal College of Physicians of Edinburgh. PMID- 4195565 TI - Contamination of operation wounds. PMID- 4195566 TI - Australia antigen and hepatitis. PMID- 4195568 TI - Junior hospital staff in training. PMID- 4195567 TI - Australia antigen and hepatitis. PMID- 4195569 TI - Thrombolytic therapy in pulmonary embolism. PMID- 4195570 TI - Prostaglandins in fertility control. PMID- 4195571 TI - Carrageenan and galactosaemia. PMID- 4195572 TI - Autoimmunity in diabetes mellitus. PMID- 4195573 TI - Children in isolation units. PMID- 4195574 TI - Selection of housemen. PMID- 4195575 TI - The fist as external cardiac pacemaker. PMID- 4195576 TI - L-dopa, parkinsonism, and depression. PMID- 4195577 TI - L-tryptophan in depression. PMID- 4195578 TI - Exercise and urinary excretion of cyclic A.M.P. PMID- 4195579 TI - Cheese reaction during debrisoquine treatment. PMID- 4195580 TI - Post-vagotomy dysphagia. PMID- 4195581 TI - Vitamin-D treatment in hypoparathyroidism. PMID- 4195582 TI - Vitamin-D treatment in hypoparathyroidism. PMID- 4195583 TI - Tolbutamide test in pituitary disease. PMID- 4195584 TI - Metabolism of progestagens. PMID- 4195586 TI - Assessing the nutritional status of children. PMID- 4195585 TI - N.B.T. test stimulated. PMID- 4195587 TI - Haemoglobin and cholesterol. PMID- 4195588 TI - Stool trypsin assay. PMID- 4195589 TI - Vaccum extraction following cord prolapse. PMID- 4195590 TI - Milk-bottle problem. PMID- 4195591 TI - Patricia Troy, L.R.C.P.I. PMID- 4195592 TI - [Electron microscopic studies of the cartilage. 2. Collagenous fibers in the cartilagenous matrix of the various bone tumors]. PMID- 4195593 TI - [Whipple's disease]. PMID- 4195594 TI - Influence of ototoxic drugs on acetylcholine-induced depression of the cochlear N1 potential. PMID- 4195595 TI - [The problem of using cadaver bone marrow for transfusion purposes. 1. In-vitro viability determination of human bone marrow cells]. PMID- 4195596 TI - Annex I. New agglutination methods for the diagnosis of brucellosis using stained antigens. PMID- 4195597 TI - Maternal and child health nursing. Nursing therapy in a combined treatment approach to rumination. PMID- 4195598 TI - [Dendritic spines of the isolated cortical gyrus of the cat]. PMID- 4195599 TI - Allergy techniques: methods and mechanisms. PMID- 4195601 TI - [Morphologic oriteria of melanoblastoma in cytologic preparations]. PMID- 4195600 TI - Guinea pig ovary and testis: localization of common gonad specific antigens. PMID- 4195602 TI - Ethanol infusions. PMID- 4195604 TI - Sim: the perfect patient. PMID- 4195603 TI - The overhead projector as a blackboard. PMID- 4195605 TI - Carcinoma of the stomach. PMID- 4195606 TI - Ringless needle holder. An aid in training of surgery residents and scrub nurses. PMID- 4195607 TI - Vibrios from fish pen slime which mimic Escherichia coli on violet red bile agar. AB - Organisms from fish pen slime which mimicked coliforms and Escherichia coli on Violet Red Bile Agar were identified as members of the genus Vibrio on the basis of metabolic and morphological characteristics. PMID- 4195609 TI - Morphological studies on equine arteritis virus. PMID- 4195608 TI - Plaque size heterogeneity: a genetic trait of lymphocytic choriomeningitis virus. AB - All of the ten strains of lymphocytic choriomeningitis virus assayed on BHK 21/13S cells showed various degrees of plaque size heterogeneity. The amount of virus released from these plaques was usually very small because of rapid photodynamic inactivation by neutral red. When virus from large and small plaques of a specific strain was plated, the same distribution of plaque size was obtained from each clone. Although it was shown that surface virus could possibly be randomly distributed at the time of addition of neutral red overlays, no virus could be isolated from nonplaque areas. Two different strains of virus (CA1371 and WE) with markedly different plaque size ranges were separated by plaque excision from plates infected with a mixture of both viruses. PMID- 4195610 TI - A novel technique for in situ demonstration of cell viability and cell injury on the respiratory surface of trachea explants. Brief report. PMID- 4195612 TI - [Experiences with a surgical intensive care unit]. PMID- 4195611 TI - Detection and some characteristics of foot-and-mouth disease (FMD) antibodies in bovine saliva. Brief report. PMID- 4195613 TI - Polybenzoid hazards. PMID- 4195614 TI - Thin-layer chromatographic identification of estrogens and progestogens in oral contraceptives. PMID- 4195615 TI - [Laboratory studies of the problem of epidemic hepatitis. II]. PMID- 4195616 TI - Investigations on the fine structure of staphylococcus in relation to its multiplication phases. PMID- 4195617 TI - [Studies on the pathogenesis of Aleutian disease in mink. I. Changes in serum proteins]. PMID- 4195618 TI - Pituitary-adrenal responsiveness during prolonged administration of estrogen and 17-acetoxy-progesterone derived progestin. PMID- 4195619 TI - [Intranuclear changes of HeLa cells by adenovirus type 8 infection]. PMID- 4195620 TI - Eosinophil leukocytes in inflammatory exudate. PMID- 4195621 TI - Immunosuppressive treatment of bronchial asthma. PMID- 4195622 TI - Electron microscopy study of the pox-like virus of Melolontha melolontha L(Coleoptera, Scarabeidae). Virus morphogenesis. PMID- 4195623 TI - Physicochemical studies of equine infectionus anemia virus. 3. Purification and electron microscopic observation of the virus. PMID- 4195624 TI - Characterization of bovine viral diarrhea viruses. V. Morphology of characteristic particles studied by electron microscopy. PMID- 4195625 TI - Electron microscopic studies on bovine ephemeral fever virus. PMID- 4195626 TI - Electron microscopic observations of equine infectious anemia (EIA) virus in cultivated horse leukocytes. (Brief report). PMID- 4195627 TI - A respiratory syncytial virus of bovine origin. PMID- 4195628 TI - [Inhibition of giant cell formation by compound 48-80 after infection with Herpesvirus hominis. II. The activation of lysosomes]. PMID- 4195629 TI - Virus-like particles occurring in cultures of stable pig kidney cell lines. Brief report. PMID- 4195630 TI - Disappointments in the management of patients with malignancy of pancreas, duodenum, and common bile duct. PMID- 4195631 TI - Selective staining of degenerating axons in the central nervous system by a simplified silver method: spinal cord projections to external cuneate and inferior olivary nuclei in the cat. PMID- 4195632 TI - Ultrastructural localization of acid phosphatase in synaptic terminals of the rat substantia gelatinosa Rolandi. PMID- 4195633 TI - [Relations between polyamines and nucleic acids. II. Biochemical and fine structural studies of peripheral nerves during Wallerian degeneration]. PMID- 4195634 TI - Methods in pancreatitis research using living acinar cells. PMID- 4195635 TI - Presence of gammaE in nasal washings and sputum from asthmatic patients. PMID- 4195636 TI - Hypersensitivity responses in monkeys. IV. Sensitization to human serum and nonacceptance of reagin. PMID- 4195637 TI - Immunologic studies on aspirin. Clinical studies with aspiryl-protein conjugates. PMID- 4195638 TI - [Alterations of alpha-2-globulin, gamma-globulin and cytotoxic antibody in canine renal allograft, with special reference to gamma-globulin deposition to the graft using direct immunofluorescent technique]. PMID- 4195639 TI - [N-acetyl-D-galactosamine in tumor cell membranes: demonstration by means of Helix agglutinins]. PMID- 4195640 TI - [Decompression of the intervertebral disk]. PMID- 4195641 TI - [True syringomyelia and gliomatosis with cavitation in children]. PMID- 4195642 TI - Toxicity of the cyanoacrylates. PMID- 4195643 TI - Corneal immune globulin distribution. PMID- 4195644 TI - [Pharmacology of circulatory active substances in stored milk]. PMID- 4195645 TI - Slow evoked cortical potentials and temporal features of stimulation. PMID- 4195646 TI - [Cortical responses evoked by light stimulation in Papio papio]. PMID- 4195647 TI - Dynamic characteristics of visual evoked potentials in the dog. I. Cortical and subcortical potentials evoked by sine wave modulated light. PMID- 4195648 TI - Dynamic characteristics of visual evoked potentials in the dog. II. Beta frequency selectivity in evoked potentials and background activity. PMID- 4195649 TI - Chemical sensitivity of neurons in long-isolated slabs of cat cerebral cortex. PMID- 4195650 TI - Inhibition and paroxysmal activity in long-isolated cortical slabs. PMID- 4195651 TI - [The role of the lemniscal projection areas and tracts in the control of extralemniscal afferents during natural sleep in the cat]. PMID- 4195652 TI - Naso-ethmoidal electrode for recording the electrical activity of the inferior surface of the frontal lobe. PMID- 4195653 TI - EEG analysis based on time domain properties. PMID- 4195654 TI - A digitally controlled constant current stimulator. PMID- 4195655 TI - An improved write-out system for low frequency wave analysers. PMID- 4195656 TI - Electroencephalographic features of posterior fossa tumours in children. PMID- 4195657 TI - Changes in the ventricular system and the EEG 24 hours after pneumoencephalography. PMID- 4195658 TI - Traumatic generalized changes in the EEG. PMID- 4195659 TI - Unusual EEG findings with subdural hematoma in a child. PMID- 4195660 TI - Frequency analysis studies on the sleep EEG of older infants. PMID- 4195661 TI - Treatment of tetanus. PMID- 4195662 TI - A method to determine the efficiency of anti-epileptic drugs on experimental cortical seizures. PMID- 4195663 TI - Narcotic and excitatory phenomena influenced by the analgesic Fentanyl. PMID- 4195664 TI - The EEG of congenitally blind adults. PMID- 4195665 TI - Evoked potentials of different sense modalities in the human thalamus. PMID- 4195666 TI - A micro-electrode technique for the comparison of micro-electroencephalograms. PMID- 4195667 TI - Fatigue as a neurological syndrome. PMID- 4195668 TI - Pseudomyotonia. PMID- 4195670 TI - Ultrasound measurements. PMID- 4195669 TI - Movements of cerebral structures. PMID- 4195671 TI - Surface marking cerebral structures in echo-encephalography. PMID- 4195672 TI - Reflex amplitudes and increasing mental load. PMID- 4195673 TI - Depth electrographic observations in an epileptic patient. PMID- 4195674 TI - Effects of acute marijuana smoking on the EEG. PMID- 4195675 TI - Interrelationships of form and latency of spike discharge from small areas of human cortex. PMID- 4195676 TI - EEG study of maturation in the puppy: photic stimulation and CO2. PMID- 4195677 TI - The EEG in deaf children. PMID- 4195678 TI - Analysis of hippocampal influence on units of mammillary region in awake, sitting squirrel monkeys. PMID- 4195679 TI - Cerebellar induced effects recorded in the cochlear nucleus of the cat. PMID- 4195680 TI - Focal high voltage beta activity: clinical correlations. PMID- 4195681 TI - Regional permeability changes in experimental convulsive disorder. PMID- 4195682 TI - Phasic changes in level of the integrated dark discharge during spontaneous saccades. PMID- 4195684 TI - Simultaneous bilateral summated cortical responses to single and to variably delayed median nerve stimulation. PMID- 4195683 TI - Lateralized EEG changes after induced convulsions. PMID- 4195685 TI - Evoked responses in Down's syndrome of young adults. PMID- 4195686 TI - EEG in Kleine-Levin syndrome. PMID- 4195687 TI - EEG findings in hydrocephalic patients with shunt procedures. PMID- 4195688 TI - Hypsarrhythmic EEG patterns in the first year of life: a 6-12 year clinical outcome. PMID- 4195689 TI - XYY and XXY inmates of security prison: EEG findings. PMID- 4195690 TI - Late brain recovery processes after drug overdose. PMID- 4195691 TI - Occipital spikes during photic stimulation and their relation to visual evoked responses in photosensitive epilepsy. PMID- 4195692 TI - The use of the autoregressive model in EEG analysis. PMID- 4195693 TI - Electro-clinical features of 50 children with tuberose sclerosis. PMID- 4195694 TI - The effect of stimulus context on evoked responses in human frontal cortex. PMID- 4195696 TI - Polarity and distribution of human visual evoked potential (VEP) components as clues to cortical topography. PMID- 4195695 TI - Investigations for the development of a model of an epileptic process. PMID- 4195697 TI - [Spectrophotometric method for quantitative determination of dicoumarin and neodiceumarin]. PMID- 4195698 TI - The dendritic tree of spinal neurons. PMID- 4195699 TI - Histogenesis of cortical layers in human cerebellum, particularly the lamina dissecans. PMID- 4195700 TI - [Immunosuppressive agents in the preventive treatment of the rejection of kidney grafts]. PMID- 4195701 TI - [Renal transplantation. Crisis of acute rejection]. PMID- 4195702 TI - Effects of gamma-globulin with vaccines used with routine immunizations. PMID- 4195703 TI - [Laboratory diagnosis in gastroenterology]. PMID- 4195704 TI - [Radiotelemetric study of intensity of acid formation in the stomach]. PMID- 4195705 TI - [Radiotelemetric study of gastric acidity in different parts of the stomach]. PMID- 4195706 TI - [Comparative value of some methods of calculation of acid and alkaline components of gastric juice]. PMID- 4195707 TI - [Use of preserved cabbage juice as test breakfast]. PMID- 4195708 TI - [Method for quantitative study of excretory processes in the stomach by A. E. Gel'fman and its clinical significance]. PMID- 4195709 TI - [Secretory function of the small intestine transplantant at different times after gastrojejunoplasty]. PMID- 4195710 TI - [Comparative evaluation of stimulants of pancreatic secretion in the diagnosis of chronic diseases of pancreas]. PMID- 4195711 TI - [Cytological diagnosis of gastric diseases]. PMID- 4195712 TI - [Sensitive method of determination of trypsin in duodenal and pancreatic juice]. PMID- 4195713 TI - [Use of differentiated carbohydrate loading and determination of lactase activity in the mucous membrane of the small intestine for functional characteristic of the small intestine]. PMID- 4195714 TI - [Losses of electrolytes, fluid and nitrogen with feces in patients after total colectomy]. PMID- 4195715 TI - [Quantitative determination of Shigella sonnei antigens in urine of patients and bacterial carriers]. PMID- 4195716 TI - [Reaction of delay of adsorption of dye at serological identification of enteropathogenic Escherichia coli]. PMID- 4195717 TI - [Composition of intestinal microflora in healthy subjects]. PMID- 4195718 TI - [Characteristics of enteropathogenic Escherichia coli O111]. PMID- 4195719 TI - [Arrangement, calculation and specificity of reaction of precipitation in agar gel in the diagnosis of rabies]. PMID- 4195720 TI - [Method of arrangement of Coombs' reaction in bacterial variation]. PMID- 4195721 TI - [A new device for the protection from atmospheric oxygen of seedings of anaerobs in celophane bags submerged into fluid medium]. PMID- 4195722 TI - [Tissue discontinuity zones in healthy and pathologic human Descemet's membrane]. PMID- 4195723 TI - The effects of various physical activity levels and dietary carbohydrate source on rat cholesterol levels. PMID- 4195724 TI - Sarcomas after inoculation of newborn hamsters with Herpes virus hominis type 2 strains. PMID- 4195725 TI - Iron in the lactating mammary gland of the rat. PMID- 4195726 TI - Reactions of proinsulin and its derivatives with antibodies to insulin. PMID- 4195727 TI - Production of heparin related mucopolysaccharides by mammalian cells in culture. PMID- 4195728 TI - Antibodies to homologous RNA in the rabbit following stimulation by exogenous RNA. PMID- 4195729 TI - Antibody-forming cells in five organs of hyperimmunized guinea pigs. PMID- 4195730 TI - Diffusion of epsilon aminocaproic acid to the joints. PMID- 4195731 TI - Metabolic neuropathies and myopathies in infancy and childhood. PMID- 4195732 TI - Uraemic polyneuropathy. PMID- 4195733 TI - [Chemotherapy of so-called atypical mycobacterioses]. PMID- 4195734 TI - [Comparison of certain indices of protein metabolism with pathomorphological changes in the liver tissue in experimental diphtheria intoxication]. PMID- 4195735 TI - [Immunochemical studies of group differences in human fetal blood sera]. PMID- 4195736 TI - [Effect of actinomycin on proliferation of the crypt epithelium of the mouse duodenum]. PMID- 4195737 TI - Virus-specific immunofluorescent and precipitin antigens and cell-free virus in the tissues of birds infected with Marek's disease. PMID- 4195738 TI - Antibodies. Structure and function of immunoglobulins. PMID- 4195739 TI - Monoclonal immunoglobulins. PMID- 4195740 TI - Cell-mediated immunity. Antigenic specificity. PMID- 4195741 TI - Immunoglobulins in asthma. PMID- 4195742 TI - The allergic response of rabbit leukocytes and platelets. PMID- 4195743 TI - Animal models of allergic diseases. Monkeys. PMID- 4195744 TI - Antigenic determinants and antibody complementarity. PMID- 4195745 TI - Mechanism of drug action in the therapy of respiratory allergy. PMID- 4195746 TI - Correlation of thyroid-function studies. PMID- 4195747 TI - The regeneration gradients and the effects of budding, feeding, actinomycin and R Nase on reconstitution in Hydra attenuata Pall. PMID- 4195749 TI - [The problem of division of taste buds]. PMID- 4195748 TI - [Effect of inhibitors of nucleinic, protein synthesis and cell division on primary immunologic response]. PMID- 4195750 TI - [Postembryonic mitotic activity in the telencephalic matrix layers of Lebistes reticulatus (Peters 1859) (Teleostei, Pisces)]. PMID- 4195751 TI - [The nerve endings in the taste buds in monkeys as compared to those in man]. PMID- 4195752 TI - [Comparative characteristics of pathohistological and cytological methods in the diagnosis of scleroma]. PMID- 4195753 TI - [Treatment of allergic rhinitis and sinusitis with corticosteroids and gamma globulin]. PMID- 4195754 TI - [Tension of the immunological reactions in patients with chronic tonsillitis]. PMID- 4195755 TI - Coagulation and fibrinolytic studies during continuous use of low dose gestagen. PMID- 4195756 TI - Bedside diagnosis of arrhythmias. PMID- 4195757 TI - [Current problems of asthma in children]. PMID- 4195758 TI - Esophagogastrectomy versus radiation therapy for midesophageal carcinoma. PMID- 4195759 TI - Extracorporeal circulation for support of palliative cardiac surgery in infants. PMID- 4195760 TI - Proposed guidelines for protocol studies. II. Plasma cell myeloma. Prepared by a Committee of the Chronic Leukemia--Myeloma Task Force, National Cancer Institute. PMID- 4195761 TI - Development of new instructional materials in the IMC network. PMID- 4195762 TI - Immunochemical studies on the serum, intestinal secretions and intestinal mucosa in patients with adult celiac disease and other forms of the celiac syndrome. PMID- 4195763 TI - Combinations of agents which induce ATP energized mitochondrial volume changes. PMID- 4195764 TI - Aminoalkenylbenzenesulfonamides with hypotensive and histamine-releasing properties. PMID- 4195765 TI - The demonstration of recent myocardial injury: a simple method suitable for routine use. PMID- 4195766 TI - [Antagonism between histamine liberators and anti-inflammatory drugs in the isolated mast cells]. PMID- 4195768 TI - Measurement of rectal electrical potential difference as an instant screening test for hyperaldosteronism. PMID- 4195767 TI - Hepatitis-associated antigen in Ugandan patients with hepatocellular carcinoma. PMID- 4195769 TI - Extraskeletal calcification complicating oral neutral-phosphate therapy. PMID- 4195770 TI - Impaired fibrinolytic response to exercise in patients with type-IV hyperlipoproteinaemia. PMID- 4195771 TI - Leucocyte phenotypes in Hodgkin's disease. PMID- 4195772 TI - Duplication of alpha-thalassaemia gene in three Greek families with haemoglobin H disease. PMID- 4195773 TI - B.C.G. vaccination and leukemia mortality. PMID- 4195774 TI - Amyloidosis: an expression of immunological tolerance? PMID- 4195775 TI - To weigh and to consider. PMID- 4195777 TI - Uneasy present, uncertain future. PMID- 4195776 TI - Screening outpatients for hyperaldosteronism. PMID- 4195778 TI - Renal disease in old people. PMID- 4195779 TI - Psychological effects of subarachnoid haemorrhage. PMID- 4195780 TI - The patient's tight. PMID- 4195782 TI - Preoperative and postoperative physiotherapy. PMID- 4195781 TI - The world's poliomyelitis. PMID- 4195783 TI - Paying for medical care. Need for debate. PMID- 4195784 TI - Deaths in United Kingdom opioid users 1965-69. PMID- 4195785 TI - Intradermal test and serological tests in suspected brucella infection in man. PMID- 4195786 TI - Coping with incontinence in the home. PMID- 4195787 TI - Screening for breast and gynaecological lesions. PMID- 4195788 TI - Legal abortion and social class. PMID- 4195789 TI - Ineffectiveness of L-dopa as supplement to penicillamine in a case of Wilson's disease. PMID- 4195790 TI - Side-effects of L-dopa in postencephalitic parkinsonism. PMID- 4195791 TI - L-dopa plus decarboxylase inhibitor in depression. PMID- 4195792 TI - Smoking and frusemide diuresis. PMID- 4195793 TI - Long-term hepatic support. PMID- 4195794 TI - Epidemic shiga dysentery in Central America. PMID- 4195795 TI - The beta-blocking effect of practolol in asthmatics. PMID- 4195796 TI - Maternity service. PMID- 4195797 TI - Medical care in the United States. PMID- 4195798 TI - Fetoprotein in pregnant African women. PMID- 4195799 TI - Contamination of meat carcasses. PMID- 4195800 TI - Sleep-walking in twins. PMID- 4195801 TI - Effect of tyrosine on plasma-I.R.I. PMID- 4195802 TI - Circulating heparin-like anticoagulant following portacaval anastomosis. PMID- 4195803 TI - Criteria of rheumatic fever. PMID- 4195804 TI - Silastic sheeting for abdominal-wall defects. PMID- 4195805 TI - Pingelap eye disease. PMID- 4195807 TI - Fluid-balance charts. PMID- 4195806 TI - 46, XY female: anti-androgenic effect of oral contraceptive? PMID- 4195808 TI - Glucose-6-phosphate-dehydrogenase deficiency and age. PMID- 4195809 TI - Pathogenesis of the glomerular lesions in acute pancreatitis. PMID- 4195810 TI - Response of dietary vitamin-B12 deficiency to physiological oral doses of cyanocobalamin. PMID- 4195811 TI - Lithium depletion and atherosclerotic heart-disease. PMID- 4195812 TI - Down's syndrome and presbyacousis. PMID- 4195813 TI - Acute myeloid leukaemia after treatment with cytostatic agents. PMID- 4195814 TI - Evolution of an atypical case of Burkitt lymphoma. PMID- 4195815 TI - The at-risk register. PMID- 4195816 TI - Venereal disease. PMID- 4195817 TI - Tests for syphilis in children for adoption. PMID- 4195818 TI - Epidemiology of gallstone disease. PMID- 4195819 TI - Negative Coombs tests in Chinese on methyldopa. PMID- 4195820 TI - Variability in urinary creatinine. PMID- 4195821 TI - Arthur Doyne Courtenay Bell, D.M. Oxon., F.R.C.P. PMID- 4195822 TI - [Atrial arrhythmia caused by ventricular extrasystole (preliminary report)]. PMID- 4195823 TI - [The behavior of the immunoglobulin level during administration of oral contraceptives]. PMID- 4195824 TI - Correction of celluar metachromasia in cultured fibroblasts in several inherited mucopolysaccharidoses. AB - Cultured fibroblasts from the genetic mucopolysaccharidoses store higher than normal amounts of the polyanionic glycosaminoglycans (mucopolysaccharides); histochemical staining with the cationic dyes toluidine blue O and Alcian blue detects such intracellular accumulation. With these stains as phenotypic markers, correction of the cellular abnormality by fibroblasts derived from different patients and their heterozygous parents has been observed among several genetic types of mucopolysaccharidoses. In this way, syndromes previously considered clinically homogeneous have been separated into distinct groups. PMID- 4195825 TI - Amino acid sequence similarities in two human anti gamma globulin antibodies. AB - Certain individuals with hypergammaglobulinemic purpura contain in their serum anti gamma globulins of restricted heterogeneity. These antibodies, characteristically of the gammaG type, were isolated from two unrelated individuals and their light polypeptide chains were subjected to amino acid sequence analysis. Although these anti gamma globulin antibodies conform to the basic VK(1) sequence, substitutions not previously encountered were found in five positions. The two antibodies were identical with each other up to residue 40 from the N-terminus of the light chains. PMID- 4195826 TI - [Some humoral characteristics of experimental amyloidosis: anti-gamma factors (rheumatoid factor) cryoglobulinemia and metachromasia of the precipitate]. PMID- 4195827 TI - [Ureterovesical reimplantation in ureteral duplication]. PMID- 4195828 TI - [Simultaneous prostatic adenomectomy and plastic surgery for hernia]. PMID- 4195829 TI - [Extrasystole]. PMID- 4195830 TI - [Biological activity of immune complex]. PMID- 4195831 TI - [Detection of surface antigens and antibodies in living cells by immunofluorescence]. PMID- 4195832 TI - Improved methods for calcium and magnesium in epidermis. PMID- 4195833 TI - [Detection of a moderate staphylococcal phage by means of antineoplastic agents]. PMID- 4195834 TI - [Effect of polysynthetic penicillins on causative agents of surgical infections in vitro]. PMID- 4195835 TI - An ultrastructural investigation of calcium-dependent granules in the rat neuropil. PMID- 4195836 TI - Demonstration of degenerating climbing fibres in the molecular layer of the cerebellum. PMID- 4195837 TI - Staining of experimentally-induced chorio-retinal lesions with Disulphine blue and Evans blue. PMID- 4195838 TI - New data and concepts concerning the ventricular gradient. PMID- 4195839 TI - Effect of r-epinephrine-impregnated retraction cord on the cardiovascular system. PMID- 4195840 TI - [Gamma E-immunoglobulin]. PMID- 4195841 TI - [Polyclonal immunoglobulinemia]. PMID- 4195842 TI - [Alpha 1-fetoprotein and cancer-specific protein]. PMID- 4195843 TI - [Resistant otorrhea and blood gamma globulin level (preliminary report)]. PMID- 4195844 TI - Cognitive factors in perceptual dysfunction. PMID- 4195845 TI - Developmental dyslexia: a constitutional disorder of symbolic perception. PMID- 4195846 TI - [Mediators in allergic reactions]. PMID- 4195847 TI - [Gamma globulin and the tourist. Should prophylaxis be recommended?]. PMID- 4195848 TI - [Oral treatment of rhinopharyngeal diseases and of their complications]. PMID- 4195849 TI - [What did Didacta 1970 bring?]. PMID- 4195851 TI - The cardio-thoracic unit. Tan Tock Seng Hospital. PMID- 4195850 TI - Kinins, kininogen and kininogenase activity in pregnancy and hepatic failure. PMID- 4195852 TI - The Golgi apparatus in chick corneal epithelium: changes in intracellular position during development. AB - The intracellular position of the Golgi apparatuses in the basal cell layer of the corneal epithelium in embryonic and hatched chicks has been studied in the light microscope by impregnating the Golgi apparatus with silver. During two distinct periods in development the Golgi apparatuses in the basal cells shift from an apical to basal position. Each of these periods correlates in time with the appearance of an acellular collagenous matrix beneath the epithelium. Examination of the basal epithelial cells in the electron microscope confirms the intracellular shifts in position of the Golgi apparatus. The results suggest that the Golgi apparatus shifts to the basal cell pole of the corneal epithelium in order to excrete connective tissue materials into the developing corneal stroma. PMID- 4195853 TI - Low-resistance junctions between cancer cells in various solid tumors. AB - Electrical coupling, which reveals the presence of specialized low-resistance intercellular junctions, has now been found in four types of tumors, Sarcoma 180, Novikoff hepatoma, and Morris hepatomas 3924-A and 7777. Coupled cancer cells were distinguished from coupled normal cells by intracellular marking techniques. Although the evidence suggests that coupling may be extensive in some cases, it is not possible to say that the coupling was normal. In particular, the results do not exclude less obvious defects in the specialized junctions, such as abnormal distribution or decreased permeability to molecules other than small inorganic ions. The results are discussed in relation to previous studies of coupling in Novikoff hepatomas and in cultures of S1801 and II cell lines. PMID- 4195854 TI - Substructure of microtubules in brain nerve cells as revealed by ruthenium red. PMID- 4195855 TI - The structure of collagen--an X-ray study. PMID- 4195856 TI - What price non-touch technique? PMID- 4195857 TI - The ultrastructure of the skin of human embryos. VII. Formation of the apocrine gland. PMID- 4195858 TI - Epidermal multinucleated giant cell in parapsoriasis guttata and eczematous dermatitis. PMID- 4195859 TI - Skin clearance of iontophoretically administered chromium (51Cr) and sodium (22Na) ions in the guinea pig. PMID- 4195860 TI - Plethysmographic recordings of skin pulses. II. Piezoelectric and photoelectric measurements in psoriasis. PMID- 4195862 TI - Studies on histamine release from skin and from peritoneal mast cells of the rat induced by heat. PMID- 4195861 TI - Experimental pruritus in the unaffected skin of patients with different itching dermatoses. PMID- 4195863 TI - Lymph-node permeability factor: a mediator in delayed hypersensitivity? Experiments using the skin window technique. PMID- 4195864 TI - Delayed reactivity to bacterial and viral extract(s) in different dermatoses. PMID- 4195865 TI - Terminology of contact dermatitis. PMID- 4195866 TI - Lupus erythematosus. Analysis of the sex- and age-distributions of the discoid and systemic forms of the disease in different countries. PMID- 4195867 TI - Linear telangiectasia. PMID- 4195868 TI - The use of standard serological tests for syphilis in screening for auto-immune connective tissue disease. Chronic biological false-positive reactions and anticomplementary activity. PMID- 4195870 TI - Benign gonococcal sepsis. A report of 36 cases. PMID- 4195871 TI - Sensitivity to antibiotics of N. gonorrhoeae isolated in 1966 and 1968 from patients in North Sweden. PMID- 4195869 TI - Non-venereal sclerosing lymphangitis of the penis. A clinicopathologic treatise. PMID- 4195873 TI - The American Association of Orthodontists Audio-Visual Library. PMID- 4195872 TI - Studies on the serum binding of vitamin B 12 in the newborn human infant. PMID- 4195874 TI - Effect of epsilon aminocaproic acid (EACA) on lysis of subcutaneous clots. PMID- 4195875 TI - The neural control of the contractile mechanism in skeletal muscle. PMID- 4195876 TI - Morphactins. PMID- 4195877 TI - Totipotency, variation and clonal development of cultured cells. PMID- 4195878 TI - The pineal gland. PMID- 4195879 TI - [Study with immunoelectrophoresis and simple radial immunodiffusion of the blood of patients with pollinosis in various evolutive stages]. PMID- 4195880 TI - OR technicians. 1. PMID- 4195881 TI - Electron microscopic study of intranuclear glycogen. PMID- 4195882 TI - The mechanism of action of gonadotrophic hormones in amphibians: the stimulation of delta5-3beta-hydroxysteroid dehydrogenase activity in testes of Xenopus laevis Daudin. PMID- 4195883 TI - Fetal erythrocytes in maternal circulation after spontaneous abortion. PMID- 4195884 TI - Functional autonomy in multinodular goiter. PMID- 4195885 TI - Mycoplasma and rheumatoid arthritis. PMID- 4195886 TI - [Characteristics of development in children of mothers with chronic liver diseases]. PMID- 4195887 TI - [Effects of the method of administering the antigen on the titre of tetanic, edematic, septic, anti beta and anti epsilon antitoxins of Welchia agni and on the distribution of proteins in blood serum]. PMID- 4195888 TI - [Oral tegment of the ascending reticular pathways of the pons in mice]. PMID- 4195889 TI - The relationship of complement to allergic disease. PMID- 4195890 TI - Role of the thyroid hormone system in suppression of anaphylaxis due to electrolytic lesion of the tuberal region of the hypothalamus. PMID- 4195892 TI - Effectiveness of topical nasal decongestants. PMID- 4195891 TI - Studies of histamine release from human leukocytes. PMID- 4195893 TI - Abnormal eosinophils, eosinophilia and basophilia in methimazole neutropenia. PMID- 4195894 TI - Nonspecific passive desensitization. XVI. Type O gamma globulin prevents desensitization by types A, B and AB gamma globulins. PMID- 4195895 TI - The role of audio-visual aids in education. PMID- 4195896 TI - [Treatment of tumors of the thyroid gland]. PMID- 4195897 TI - [Acute infectious hepatitis in childhood. Epidemiological findings in the city and province of Mantova and clinico-statistical studies in 248 subjects hospitalized in the 4-year period of 1965-1968]. PMID- 4195898 TI - [Immunohistological study of a case of exanthema associated with infection caused by parainfluenza virus, type 3]. PMID- 4195900 TI - Reliability and convergent validity of a symbolic test for authoritarianism. PMID- 4195899 TI - Development genetics of the lactate dehydrogenase isozymes of fish. PMID- 4195901 TI - Prevention of posttransfusion hepatitis by gamma-globulin. Preliminary report. PMID- 4195902 TI - Structures of schizophrenic forms of expression. PMID- 4195903 TI - Typical findings in pathological grief. PMID- 4195904 TI - Sheep, minks, savages and presenile dementia. The story of slow viruses. PMID- 4195905 TI - [Refsum's disease. Histological, ultrastructural and biochemical study of a peripheral nerve biopsy. Addendum to the report of 1966]. PMID- 4195906 TI - Human secretory immunoglobulins. I. Salivary secretions from individuals with normal or low levels of serum immunoglobulins. PMID- 4195907 TI - Analysis of results of the 1969 comprehensive chemistry survey of the College of American Pathologists. PMID- 4195908 TI - Low protein intake and response to Escherichia coli 055 infection in patas monkeys. PMID- 4195909 TI - Microscopic evaluation of the effects of some vital staining agents on growing bone in rabbits. PMID- 4195910 TI - A new virus in a spontaneous mammary tumor of a rhesus monkey. PMID- 4195911 TI - Invasion of cartilage by an experimental rat tumor. PMID- 4195912 TI - Microspectrofluorometric comparison of acridine orange dye binding in meristematic and parenchymal nuclei of the orchid embryo. PMID- 4195913 TI - Histological staining properties of procion yellow M4RS. PMID- 4195914 TI - Chlorphenesin: a new inhibitor IgE-mediated histamine release. PMID- 4195915 TI - Cytoplasmic inclusions and nuclear changes in cells infected with influenza-B viruses. PMID- 4195916 TI - The laboratory diagnosis of vaginal infections caused by Trichomonas and Candida (Monilia) species. PMID- 4195917 TI - The experimental infection of calves with bacteriaemia-producing strains of Escherichia coli: the influence of colostrum. PMID- 4195918 TI - The pathogenesis of Sendai virus infection in the mouse lung. PMID- 4195920 TI - Substructure in negatively stained flagella of Pteridium spermatozoids. PMID- 4195919 TI - Fine structure of early cartilage calcification. PMID- 4195921 TI - Structural differences between old and young negatively stained red cell membranes. PMID- 4195922 TI - A study of the anatomy of the prostate, prostatic urethra and the urinary sphincter system. PMID- 4195923 TI - The transurethral resection reaction secondary to intraperitoneal extravasation of irrigating solution. PMID- 4195924 TI - Lethal freezing temperatures of the surgical capsule and cryosurgery of the prostate. PMID- 4195925 TI - Cellular compartmentalization of herpesvirus antigens during viral replication. AB - HEp-2 cells infected with herpes simplex virus develop five distinct immunofluorescent elements. Three (small nuclear granules, large nuclear granules, and an amorphous mass filling the nucleus) contain antigens which react with a rabbit serum prepared against boiled infected cell debris. A labeled pool of human antibody revealed antigens making up cytoplasmic granules and those responsible for a diffuse cytoplasmic fluorescence. All five immunofluorescent elements are demonstrable with a rabbit serum prepared against unheated infected cell debris. Viral antigens are segregated in the nucleus or in the cytoplasm; within the limits of detection, each antigen accumulates in one compartment only. The antigens responsible for the diffuse cytoplasmic fluorescence and for the amorphous nuclear mass are synthesized early in infection; they are formed in arginine-deprived cells and exist in a form which does not sediment on centrifugation at 79,000 x g for 2 hr. The antigens comprising the nuclear and cytoplasmic granules arise relatively late in infection; they are not formed in arginine-deprived cells, and they are readily sedimented on centrifugation at 79,000 x g for 2 hr. Heating (60 C for 2 hr) confers on one or more cytoplasmic viral antigens a new specificity; the altered antigens are demonstrable with labeled rabbit anti-boiled infected cell serum which normally does not combine with cytoplasmic antigens. PMID- 4195927 TI - A histochemical and ultrastructural study of intimal bodies of horse arterioles. PMID- 4195926 TI - Reovirus-directed ribonucleic acid synthesis in infected L cells. AB - Reovirus replication in L-929 mouse fibroblasts was unaffected by 0.5 mug of actinomycin per ml, a concentration which inhibited cell ribonucleic acid (RNA) synthesis by more than 90%. Under these conditions of selective inhibition, the formation of both single-stranded and double-stranded virus-specific RNA was detected beginning at 6 hr after infection. The purified double-stranded RNA was similar in size and base composition to virus RNA and presumably was incorporated into mature virus. The single-stranded RNA formed ribonuclease-resistant duplexes when annealed with denatured virus RNA but did not self-anneal, thus indicating that it includes copies of only one strand of the duplex. The single-stranded RNA was polyribosome-associated and may function as the virus messenger RNA. Production of both types of virus-induced RNA required protein synthesis 6 to 9 hr after infection. At later times in the infectious cycle, only double-stranded RNA synthesis was dependent on continued protein formation. PMID- 4195928 TI - Levitation in treatment of large-area burns. PMID- 4195929 TI - Long-term results with iodine-125 treatment for toxic diffuse goitre. PMID- 4195930 TI - Probability of a woman with advanced breast cancer responding to adrenalectomy or hypophysectomy. PMID- 4195931 TI - Long-term continuous intracranial-pressure monitoring by means of a modified subdural pressure transducer. PMID- 4195932 TI - Rapid diagnosis of influenza by immunofluorescent techniques. PMID- 4195933 TI - Lead and delta-aminolaevulinic acid dehydratase levels in mentally retarded children and in lead-poisoned suckling rats. PMID- 4195934 TI - Natural gas: friend or foe? PMID- 4195935 TI - Treatment of chronic hypoxaemia. PMID- 4195936 TI - Occupational health: the next move? PMID- 4195938 TI - Impasse. PMID- 4195937 TI - Experiments on living animals. PMID- 4195939 TI - Cytological examination of endometrium. PMID- 4195940 TI - Printing of The Lancet. PMID- 4195941 TI - After the earthquake. PMID- 4195942 TI - Regional service for acute and chronic dialysis of children. PMID- 4195943 TI - Immunosurveillance and cancer. PMID- 4195944 TI - Ten years of boarding-out in Somerset. PMID- 4195945 TI - Increasing frequency of a syndrome of multiple osseous defects? PMID- 4195946 TI - Therapeutic abortion by local administration of prostaglandin. PMID- 4195947 TI - Social work in general practice. PMID- 4195948 TI - S.H. antigen and chronic liver disease. PMID- 4195949 TI - Liver disease in ulcerative colitis. PMID- 4195950 TI - Muscle relaxation during anaesthesia. PMID- 4195951 TI - Caesarean section under local anaesthesia. PMID- 4195953 TI - Severe myositis during recovery from influenza. PMID- 4195952 TI - Fatal massive liver necrosis after repeated methoxyflurane anaesthesia. PMID- 4195954 TI - Treatment of Parkinsonism with L-dopa and amantadine. PMID- 4195955 TI - Mental symptoms in parkinsonian patients treated with L-dopa. PMID- 4195956 TI - L-asparaginase and pancreatitis. PMID- 4195957 TI - In-vitro cytotoxicity of L-asparaginase on rodent and human neoplastic cells. PMID- 4195958 TI - Detection of bacteriuria. PMID- 4195959 TI - Blood-groups, cholesterol, and myocardial infarction. PMID- 4195961 TI - Amitriptyline and cardiac disease. PMID- 4195960 TI - Effect of dietary fats and carbohydrates on serum-lipids in the rat. PMID- 4195962 TI - Tropical sprue in the Caribbean. PMID- 4195963 TI - Chronic diarrhoea and marasmus. PMID- 4195964 TI - Lymphocyte transformation in coeliac disease. PMID- 4195965 TI - Lactose intolerance following measles. PMID- 4195966 TI - Carrageenan and the human gut. PMID- 4195967 TI - Glomerular lesions in acute pancreatitis. PMID- 4195968 TI - The at-risk register. PMID- 4195969 TI - Recurrence risks for cleft lip and cleft palate in British Columbia Indians. PMID- 4195971 TI - Medical care in the United States. PMID- 4195970 TI - The handless and footless families of Brazil. PMID- 4195972 TI - Long-term remission in acute leukaemia. PMID- 4195973 TI - Toxicity of dithiothreitol. PMID- 4195974 TI - Adam Patrick. PMID- 4195975 TI - Hypothalamo-pituitary-adrenal function in asthmatic patients receiving long-term corticosteroid therapy. PMID- 4195976 TI - Acetone in diabetic ketoacidosis. PMID- 4195977 TI - Small blood-vessels in migraine. PMID- 4195978 TI - Delayed psychosis due to L.S.D. PMID- 4195979 TI - Familial sideroblastic anaemia: problem of Xg and X chromosome inactivation. PMID- 4195980 TI - Serum gamma-glutamyl transpeptidase as a diagnostic aid. PMID- 4195982 TI - Role of myocardium in the modern epidemic of ischaemic heart-disease. PMID- 4195981 TI - Heparin treatment for post-partum renal failure with microangiopathic haemolytic anaemia. PMID- 4195983 TI - Combined treatment of leukaemias and reticuloses. PMID- 4195984 TI - Lung cancer in haematite miners. PMID- 4195985 TI - Like gout. PMID- 4195986 TI - Amantidine and influenza in general practice. PMID- 4195987 TI - The McMaster medical school at Hamilton, Ontario. PMID- 4195989 TI - Burkitt lymphoma and malaria. PMID- 4195988 TI - Trimethylaminuria: the fish-odour syndrome. PMID- 4195990 TI - E.B. virus and lymphomas. PMID- 4195991 TI - Leucocyte phenotypes in Hodgkin's disease. PMID- 4195992 TI - Human lymphoid cell lines: potential hazards to laboratory workers. PMID- 4195993 TI - Intranuclear aggregates in the liver of a patient with serum hepatitis. PMID- 4195994 TI - Iron therapy for haemodialysis patients. PMID- 4195996 TI - Triethylene tetramine dihydrochloride in Wilson's disease. PMID- 4195995 TI - Acute myeloid leukaemia after treatment with cytostatic agents. PMID- 4195997 TI - Coagulation abnormalities in generalised herpes-simplex infection of newborn. PMID- 4195998 TI - Sea-blue-histiocyte syndrome. PMID- 4195999 TI - L-tryptophan in depression. PMID- 4196000 TI - Contaminated antiseptic solutions. PMID- 4196001 TI - The choroid plexus in African sleeping-sickness. PMID- 4196002 TI - Beta-blocking effect of practolol in asthmatics. PMID- 4196003 TI - Perinatal mortality. PMID- 4196004 TI - Plasticisers from P.V.C. PMID- 4196005 TI - Tetraploidy in cells cultured from amniotic fluid. PMID- 4196006 TI - Sympathomimetic agents and serum-lipid levels. PMID- 4196007 TI - Intrauterine administration of prostaglandins. PMID- 4196008 TI - Lactic acidosis in diabetic coma. PMID- 4196009 TI - Solutions for kidney storage. PMID- 4196010 TI - Amyloidosis, Alzheimer's disease, and ageing. PMID- 4196011 TI - Phenformin and blood-urea. PMID- 4196012 TI - Rubella and rheumatoid arthritis. PMID- 4196013 TI - Trisomy 18. PMID- 4196014 TI - Epileptic death due to suffocation during sleep. PMID- 4196015 TI - Treatment of nephroblastoma and neuroblastoma: M.R.C. trials. PMID- 4196016 TI - Klebsiella in faecal flora of renal-transplant patients. PMID- 4196017 TI - Leg-vein thrombosis following myocardial infarction. PMID- 4196018 TI - Seasonal incidence and mortality of ischaemic heart-disease. PMID- 4196019 TI - Metabolic findings in hyperosmolar, non-ketotic diabetic stupor. PMID- 4196020 TI - Sciatica caused by sacral-nerve-root cysts. PMID- 4196021 TI - Fundamental physiological role of parathyroid hormone in acid-base homoeostasis. PMID- 4196022 TI - Bacteria in faeces and food. PMID- 4196023 TI - Thyroid-function tests. PMID- 4196024 TI - Making plans. PMID- 4196025 TI - Delayed overture. PMID- 4196026 TI - Safer roads? PMID- 4196027 TI - The last of the sixties. PMID- 4196029 TI - More than enough. PMID- 4196028 TI - Apathetic thyrotoxicosis. PMID- 4196030 TI - Tasmania's medical school. PMID- 4196031 TI - The relief operation in former Biafra. PMID- 4196032 TI - Audiovisual aids in medical schools. PMID- 4196033 TI - Experiments on living animals. PMID- 4196034 TI - Blood-groups and hypopharyngeal cancer. PMID- 4196035 TI - Immune responses in malaria. PMID- 4196036 TI - Social work in general practice. PMID- 4196037 TI - Social work in general practice. PMID- 4196038 TI - Social work in general practice. PMID- 4196039 TI - Use of the casualty department. PMID- 4196040 TI - Emergency call service. PMID- 4196041 TI - At-risk register. PMID- 4196043 TI - Epidemiology of gallstone disease. PMID- 4196042 TI - Mortality in urinary schistosomiasis. PMID- 4196044 TI - Spontaneous intracerebral haematoma in a patient undergoing haemodialysis. PMID- 4196045 TI - Dilution and transfusion. PMID- 4196046 TI - Coordinated care of the child with spina bifida. PMID- 4196047 TI - Virus-like particles in infectious hepatitis. PMID- 4196048 TI - Au antigen in liver cirrhosis. PMID- 4196049 TI - Infectious hepatitis and Down's syndrome. PMID- 4196050 TI - Aplastic anaemia and infectious hepatitis. PMID- 4196051 TI - H.A.A. at the barber's? PMID- 4196052 TI - Tropical sprue in Africa. PMID- 4196053 TI - Intestinal transport of fructose. PMID- 4196054 TI - Carrageenan: effects in animals. PMID- 4196055 TI - Serum gamma-glutamyl transpeptidase as a diagnostic aid. PMID- 4196056 TI - Preservation of serum-acid-phosphatase. PMID- 4196057 TI - Junior hospital staff in training. PMID- 4196058 TI - Effect of propranolol on serum-thyroxine. PMID- 4196059 TI - Lay hypochondria. PMID- 4196060 TI - Effect of allopurinol on pyrimidine metabolism in the Lesch-Nyhan syndrome. PMID- 4196061 TI - Delayed psychosis due to L.S.D. PMID- 4196062 TI - Abnormal pharmacokinetics of phenytoin in a patient with uraemia. PMID- 4196063 TI - Sex-chromatin and menstrual cycle. PMID- 4196064 TI - Small blood-vessels in migraine. PMID- 4196065 TI - Register of interpreters. PMID- 4196066 TI - Rapid axonal transport of sulfated mucopolysaccharide proteins. AB - When sulfur-35-labeled sodium sulfate is injected intraocularly in the goldfish, labeled sulfated mucopolysaccharides rapidly appear in the contra-lateral optic tectum of the brain, demonstrating the axonal flow of sulfated mucopolysaccharides. The transport rate is the same as that observed for proteins labeled after intraocular injection of tritiated proline. Treatment of the sulfur 35-labeled material with precipitants and enzymes reveals the presence of substances with properties similar to those of heparan sulfate (the major component) and chondroitin sulfate. Dermatan sulfate was not detected. PMID- 4196068 TI - Tumors of the skin. Considerations on total excision. PMID- 4196067 TI - Radioresistance of cooperative function of carrier-specific lymphocytes in antihapten antibody responses. AB - Transfer of lymphoid cells from strain-2 guinea pigs immunized to bovine gamma globulin into syngeneic recipients immunized with dinitrophenyl ovalbumin markedly enhances the secondary antidinitrophenyl response of the recipient to challenge with dinitrophenyl-bovine gamma globulin. This function of the carrier bovine gamma globulin-specific cells is resistant to irradiation with up to 5000 rads, although the capacity of the irradiated cell population to transfer immunologic memory for bovine gamma globulins or to be stimulated by antigen to synthesize DNA in vitro is abolished by this treatment. PMID- 4196069 TI - Benzene hexachloride poisonong. PMID- 4196071 TI - Studies on comparison of staining of Treponema pallidum with that of Borrelia recurrentis as seen from long-term preservation of the specimen. II. Negative staining. PMID- 4196070 TI - Current concepts of the pathogenesis and management of asthma. PMID- 4196072 TI - Study on histologic changes of periodontal membrane incident to experimental tooth movement. PMID- 4196073 TI - Induction of T antigen, new surface antigen, and transplantation immunity by a nontumorigenic variant of type 3 bovine adenovirus. PMID- 4196074 TI - Automation of a quantitative immunochemical microanalysis of human serum transferrin: a model system. PMID- 4196075 TI - A simple way to index, file and retrieve slides. PMID- 4196076 TI - Rubella vaccine. PMID- 4196077 TI - Slides add emphasis to food service training program. PMID- 4196078 TI - Studies on the morphopoiesis of the head of bacteriophage T-even. 8. Multilayered polyheads. PMID- 4196079 TI - Electron microscope observations on actomyosin and actin preparations from Physarum polycephalum, and on their interaction with heavy meromyosin subfragment I from muscle myosin. PMID- 4196080 TI - [Immunoglobulin fraction and reagin activity in the nasal fluid in nasal allergy]. PMID- 4196081 TI - [Immunological studies of the palatine tonsil--with special reference to serum immunoglobulins and complement]. PMID- 4196082 TI - [Effects of the substances causing air pollution (exhaust fume, sulfurdioxide) villus of the tracheal mucosa in guinea pigs--electron-microscopic observation]. PMID- 4196083 TI - Preservation of intercellular substances by the cationic dye alcian blue in preparative procedures for electron microscopy. PMID- 4196084 TI - [Immunoglobulin deficiency syndrome and immunological deficiency syndromes]. PMID- 4196085 TI - [Colorimetric determination of the proteolytic activity of the urine in some diseases]. PMID- 4196086 TI - The drops of life: fluids and electrolytes. PMID- 4196087 TI - The drops of life. I.V. therapy as a nursing responsibility. PMID- 4196088 TI - Hypervolaemia in status asthmaticus. PMID- 4196090 TI - RN reports from Chicago. PMID- 4196089 TI - Good-by, Mary. PMID- 4196091 TI - Effect of L-dopa on seborrhoea of parkinsonism. PMID- 4196093 TI - Death is a family matter. PMID- 4196092 TI - Diagnosing thyroid carcinoma. PMID- 4196094 TI - Abortion: a stormy subject. PMID- 4196095 TI - [Cardiac rhythm disorders (current perspectives)]. PMID- 4196096 TI - A multi-media curricular approachin the making. PMID- 4196097 TI - Carcinogenic natural products. PMID- 4196098 TI - Irradiated humans: microbial flora, immunoglobulins, complement (C'3), transferrin, agglutinins, and bacteriocidins. PMID- 4196099 TI - [Igee and in vitro diagnosis of reagin mediated diseases]. PMID- 4196100 TI - [Optical and electron study of the morphology of nerve transmission at the level of the central nervous system. Findings with a new technic]. PMID- 4196101 TI - [Neuroglia in crustacea. I. Neuroglia in interganglionic connections]. PMID- 4196102 TI - [Advantages of the educational films in prosthetic dentistry]. PMID- 4196103 TI - "Plotting" the basic curriculum. PMID- 4196104 TI - The OR nurse in the patient care circuit. PMID- 4196105 TI - Editorial: the challenge and the future in nursing. PMID- 4196106 TI - Anesthesia for the aged. PMID- 4196107 TI - Change--can nursing make it? PMID- 4196109 TI - An historical review of "Die Symbolik des Traumes". (Chapters I-VI). PMID- 4196108 TI - [Immunosuppressive therapy of lupoid hepatitis]. PMID- 4196110 TI - [Immunochemical studies on split products of human gamma globulins. Studies in serums with hypergammaglobulinemia and paraproteinemia]. PMID- 4196111 TI - Idiopathic infantile arterial calcification--a misnomer? PMID- 4196112 TI - [Presence of tumor-specific immunoglobulins in patients with serous papillary adenoma of the ovary]. PMID- 4196114 TI - Selective zinc iodide-osmium tetroxide impregnation of synaptoid vesicles in the rat neurohyophysis. PMID- 4196113 TI - [Histo-immunological detection of immunoglobulins IgG, IgM and IgA in serous papillary adenocarcinoma of the ovary]. PMID- 4196115 TI - Thyroid function tests: a review. PMID- 4196117 TI - [Karyometric determinations and their relationship to the clinic in infantile parablastic leukemias]. PMID- 4196116 TI - [Cytophotometric determination of nucleic acids in mononuclear blood cells]. PMID- 4196118 TI - [The submicroscopic structure of a new cytoplasmic organelle in lymphocytes and lymphoid cells]. PMID- 4196119 TI - Increased glycogen accumulation in normal stimulated lymphocytes in vitro by modifying the conditions of cultivation. PMID- 4196120 TI - A comparative cytochemical study of leukocytes of some animal species. PMID- 4196121 TI - Bone marrow and spleen interrelation in local irradiation: data of cytometry and Fe59 incorporation. PMID- 4196123 TI - The acid-base conditions of ACD blood during storage. PMID- 4196122 TI - [Plasma erythrocyte sedimentation under the effect of heat and other stabilizing factors]. PMID- 4196124 TI - Naturally occurring anti-CW antibody and the frequency of the CW antigen in blood donors of the county Pest. PMID- 4196125 TI - Effects of deleterious oral habits on the dento-facial complex. PMID- 4196126 TI - Clinical and metabolic study in hypothyroidism. PMID- 4196127 TI - Modern management of the Rh incompatible pregnancy. PMID- 4196128 TI - Seminar on care of the newborn. IV. Newborn hematologic problems. PMID- 4196129 TI - The quantitation of nerve biopsy findings. PMID- 4196130 TI - Cytology of the tonsils. PMID- 4196131 TI - [Space, time and rhythm in the correction of speech disorders with audiovisual methods]. PMID- 4196132 TI - Technical aids in surgery. The palliative operation for obstructive jaundice due to carcinoma of the pancreas. PMID- 4196133 TI - The effect of experimental constriction on the structure of the sciatic nerve. PMID- 4196134 TI - Balloon atrial septostomy in complete transposition of the great vessels. PMID- 4196135 TI - [Clearance mechanism of the RES following application of high doses of Au-198 with regard to the kinetics of distribution and adaptability]. PMID- 4196136 TI - The decision making process in cancer patient care. PMID- 4196137 TI - George Nicholas Papanicolaou (1883-1962). PMID- 4196138 TI - Classes in oncology: George Nicholas Papanicolaou's new cancer diagnosis presented at the Third Race Betterment Conference, Battle Creek, Michigan, January 2-6, 1928, and published in the Proceedings of the Conference. PMID- 4196139 TI - Rhabdomyosarcoma of the middle cranial fossa. PMID- 4196140 TI - Evaluation of EDTA as the chelator in the biuret reagent. PMID- 4196141 TI - [Hazard-adapted therapy of acquired idiopathic nephrotic syndromes in children]. PMID- 4196142 TI - Clinical and immunological studies following immunotherapy with aqueous and alum precipitated reagweed fraction A. PMID- 4196143 TI - IgE levels, antibodies against smooth muscle and eosinophilia in asthmatic patients and normal controls. PMID- 4196144 TI - IgE levels in external secretions. PMID- 4196145 TI - Membrane antigens of human colonic carcinoma and non-tumoral colonic mucosa: results obtained with a new isolation method. PMID- 4196146 TI - The therapeutic dietitian's role in the Alimentation Group. PMID- 4196147 TI - Relationship between a metabolic rhythm and emergence rhythm in Drosophila melanogaster. PMID- 4196148 TI - Physiological factors in the courtship processing of Drosophila melanogaster. PMID- 4196149 TI - Morphogenetic effects of juvenile hormone and juvenile hormone mimics on adult development of Drosophila. PMID- 4196150 TI - Effects of protein-calorie malnutrition on drug metabolism in rat liver microsomes. PMID- 4196152 TI - Quantitative comparison of biological dressings. PMID- 4196151 TI - The separate effects of protein and calorie malnutrition on the development and growth of rat bones and teeth. PMID- 4196153 TI - Carotid perfusion hypothermia for brain surgery using cardiac arrest without bypass. PMID- 4196155 TI - Professional standards review organizations. Analysis of their development and implementation based on a preliminary review of the Hospital Admission and Surveillance Program in Illinois. PMID- 4196154 TI - Neurologic disorders following live measles-virus vaccination. PMID- 4196156 TI - Bacteriological foundations of hospitalism. PMID- 4196157 TI - [Urological problems in paraplegics]. PMID- 4196159 TI - [Promotion of patient oriented behavior in nursing education]. PMID- 4196158 TI - [Nursing education and planning of professional education]. PMID- 4196160 TI - [Inservice education. Report from the practice in a main clinical center]. PMID- 4196161 TI - [Total patient care. V. Aids in practical education]. PMID- 4196162 TI - [Home nursing]. PMID- 4196163 TI - [Creutzfeldt-Jakob's disease. A human spongiform viral encephalopathy]. PMID- 4196164 TI - Clinical and physiopathological considerations on the hyperosmolar states with or without ketoacidosis. PMID- 4196165 TI - Whole body counter studies of iron absorption in patients with subtotal gastrectomy. PMID- 4196166 TI - The use of a nonabsorbable indicator ( 51 CrCl 3 ) method for measuring 14 C labelled fatty-acid absorption in the intestine. PMID- 4196167 TI - Lower pH limit for the existence of blue-green algae: evolutionary and ecological implications. AB - Observations on a wide variety of acidic environments, both natural and man-made, reveal that blue-green algae (Cyanophyta) are completely absent from habitats in which the pH is less than 4 or 5, whereas eukaryotic algae flourish. By using enrichment cultures with inocula from habitats of various pH values, the absence of blue-green algae at low pH was confirmed. PMID- 4196168 TI - Sexual differentiation of pituitary function: apparent difference bewteen primates and rodents. AB - Surges in luteinizing hormone secretion resembling those which occur spontaneously during the menstrual cycle were induced by acute elevations in circulating estrogen concentrations in both male and female rhesus monkeys gonadectomized in adulthood. These experiments demonstrate that in primates, in contrast to rodents, exposure of the hypothalamohypophyseal unit to androgens throughout fetal and postnatal development does not prevent the differentiation of the control system that governs cyclic gonadotropin secretion. PMID- 4196169 TI - Sexual behavior in rhesus monkeys after vasectomy. AB - Vasectomy had no statistically significant effect on the sexual behavior of vigorous adult rhesus monkeys. Of two groups of males matched for level of sexual performance, one was vasectomized and the other underwent sham vasectomy. In sex tests administered within the month after surgery, the groups showed no difference (P .05) in rate of mounting, intromission, or ejaculation, or in any other measure of sexual or sex-related behaviors. PMID- 4196170 TI - Polychlorinated biphenyl- and triphenyl-induced gastric mucosal hyperplasia in primates. AB - Polychlorinated biphenyl or triphenyl ingestion by subhuman primates for 3 months produced hyperplasia and dysplasia of the gastric mucosa. The concentration of the biphenyl within the experimental diet was less than an order of magnitude greater than that occurring in random food samples sold in the United States and less than levels which have occurred in food products as a result of industrial accidents. The increased cellularity, abnormal dysplastic growth pattern, and invasion of the adjacent tissue region indicate compromised gastric function and are suggestive of an eventual neoplastic transformation. PMID- 4196172 TI - [Economizing in intramural health care]. PMID- 4196171 TI - Motor cortex reflexes associated with learned movement. AB - In primates, sensory input can generate reflex motor cortex output in association with learned movement when the sensory input has a strong and direct connection to the motor cortex-for example, when a stimulus calling for repositioning of the hand consists of a perturbation of hand position. This finding supports the proposal that neurons of primate motor cortex may function in a transcortical servo-loop. PMID- 4196173 TI - [Morphology of type A, B, and C oncornaviruses of continuous human and animal cell lines]. PMID- 4196174 TI - [Type C oncornavirus in swine embryonic kidney continuous cell culture (SPEV)]. PMID- 4196175 TI - [Population genetics of vertebrate viruses]. PMID- 4196176 TI - Reproductive function in the human male. Report of a WHO scientific group. PMID- 4196177 TI - The Medical Society of Copenhagen 1772-1972. PMID- 4196178 TI - Health hazards in the use of the laser microprobe for toxic and infective samples. PMID- 4196179 TI - The anginal syndrome associated with normal coronary arteriograms. Report of a six year experience. PMID- 4196180 TI - Oxidation of catechol in plants. 3. Purification and properties of the diphenylene dioxide 2,3-quinone-forming enzyme system from Tecoma leaves. PMID- 4196181 TI - The characterization and regulatory properties of pyruvate kinase from cotton seeds. PMID- 4196182 TI - Fat metabolism in higher plants. LVI. Distribution and nature of biotin in chloroplasts of different plant species. PMID- 4196183 TI - Structure and function of amylases. II. Multiple forms of bacillus subtilis amylase. PMID- 4196184 TI - Carbonic anhydrase catalyzed oxygen-18 exchange between bicarbonate and water. PMID- 4196185 TI - Recovery of function: implications for theories of brain function. PMID- 4196186 TI - The hippocampus and behavioral maturation. PMID- 4196187 TI - The effects of vibratory and electrical stimulation on habituation in the ciliated protozoan, Spirostomum ambiguum. PMID- 4196188 TI - The involvement of calcium in contractility in the ciliated protozoan, Spirostomum ambiguum. PMID- 4196189 TI - Fluorescence polarization and pigment orientation in photosynthetic bacteria. PMID- 4196190 TI - Role of cell wall antolysin in chain formation by a mutant strain of Streptococcus faecalis. PMID- 4196191 TI - Effects of calcium and bound sialic acid on the viscosity of mucin. PMID- 4196192 TI - Representation of the cochlear partition of the superior temporal plane of the macaque monkey. PMID- 4196193 TI - Sulfatide synthesis in neurons: a defect in mice with a hereditary myelination disorder. PMID- 4196194 TI - Distinct projections to the red nucleus from the dentate and interposed nuclei in the monkey. PMID- 4196195 TI - Lithium stimulates secretion of acetylcholine in the absence of extracellular calcium. PMID- 4196196 TI - Brain amino acids in baboons with light-induced epilepsy. PMID- 4196197 TI - [Incertae sedis parasites in comparative pathology]. PMID- 4196198 TI - Human prolactin. PMID- 4196199 TI - Isolation and partial characterization of immunoglobulin from a urodele amphibian (Necturus masculosus). PMID- 4196201 TI - Quantitative analysis of activity in eye muscle motoneurons during saccadic eye movements and positions of fixation. PMID- 4196200 TI - The bentonite granuloma. Characterization of a model system for infectious and foreign body granulomatous inflammation using soluble mycobacterial, histoplasma and schistosoma antigens. PMID- 4196202 TI - Influence of saccadic eye movements on unit activity in simian lateral geniculate and pregeniculate nuclei. PMID- 4196203 TI - Unit activity in prefrontal cortex during delayed-response performance: neuronal correlates of transient memory. PMID- 4196204 TI - GLC determination of nitroglycerin and isosorbide dinitrate in human plasma. PMID- 4196205 TI - Kinetics of -lactamase inactivation of penicillins I: effect of side-chain structure, ionic strength, pH, and temperature. PMID- 4196206 TI - Selenium heterocycles. 8. Synthesis and antibacterial activity of selenosemicarbazide and 1,3,4-selenadiazolylcarbamic acid esters. PMID- 4196207 TI - Field application of immunodiffusion and complement fixation tests for diagnosis of equine infectious anemia. PMID- 4196208 TI - Relationship between histopathological and serological findings in field cases of equine infectious anemia. PMID- 4196209 TI - Some characteristics of high macarbomycin-resistant mutants of Escherichia coli isolated from gnotobiotic pigs. PMID- 4196210 TI - Short term heritable changes affecting viability in Drosophila melanogaster. PMID- 4196211 TI - [Nutritional problems in surgery]. PMID- 4196212 TI - [Giardia lamblia and immunoglobulins, disaccharidases, lactic acid and fecal pH]. PMID- 4196213 TI - [Fracture healing using oxyphenbutazone]. PMID- 4196214 TI - Blood carbonic anhydrase activity in the newborn. PMID- 4196215 TI - Total intravenous nutrition. Experience with fat emulsions and hypertonic glucose. PMID- 4196216 TI - Prevention of postoperative ketosis in the diabetic. Use of high-caloric intravenous solutions. PMID- 4196217 TI - Venobronchial fistula. A rare complication of central venous catheterization for parenteral hyperalimentation. PMID- 4196218 TI - Photic stimulation and visual physiology: implications for behavioral studies. PMID- 4196219 TI - Reversal learning in the developing malnourished rhesus monkey. PMID- 4196220 TI - H-2 histocompatibility alloantigens. Some biochemical properties of the molecules solubilized by NP-40 detergent. PMID- 4196221 TI - RNA polymerase from vegetative cells and spores of Bacillus cereus T. II. Peptide composition. PMID- 4196222 TI - The reaction of hydroxylamine with 4-thiouridine. PMID- 4196223 TI - The regulation of cell growth. I. Identification and partial characterization of a DNA synthesis stimulating factor from the serum of partially hepatectomized rats. PMID- 4196224 TI - Colour coding in rhesus monkey prestriate cortex. PMID- 4196225 TI - Exploratory behavior of cebus monkeys after having been reared in partial isolation. PMID- 4196226 TI - Tacitin: a preliminary evaluation in chronic alcoholic patients presenting the target symptomatology of anxiety. PMID- 4196227 TI - Thioridazine for newly admitted psychiatric patients. PMID- 4196228 TI - U-28,774 (ketozolam): an early evaluation of a new antianxiety agent. PMID- 4196229 TI - Clinical evaluation of a possible catechol-O-methyl transferase inhibitor in endogenous depression. PMID- 4196230 TI - Topical clotrimazole in dermatophytosis. PMID- 4196231 TI - Chlorazepate dipotassium in the treatment of anxiety associated with chronic gastrointestinal disease. PMID- 4196232 TI - The use of fluphenazine enanthate in psychotic patients. PMID- 4196233 TI - A double blind, phase I clinical study oxazepam and protriptyline combined. PMID- 4196234 TI - Hemocytic changes associated with the encapsulation and melanization of some insect parasites. PMID- 4196235 TI - [Carbonic anhydrase in erythrocytes as a maturity index in comparison with parameters of hemoglobin ontogenesis]. PMID- 4196236 TI - [Clinical aspects of the duodenal diverticulum]. PMID- 4196237 TI - The cutaneous mucinoses. PMID- 4196238 TI - Mast cell infiltrates of the skin and the mastocytosis syndrome. PMID- 4196239 TI - Temperature-sensitive initiation of chromosome replication in a mutant of Bacillus subtilis. AB - A mutant of Bacillus subtilis Ts37 has been isolated in which deoxyribonucleic acid (DNA) synthesis is inhibited at high temperature. The results presented here indicate that the process of initiation of DNA replication is temperature sensitive in this mutant. After shifting to 45 C, DNA increases 40 to 50% before synthesis ceases; an inhibition of protein synthesis permits an equivalent amount of DNA to be synthesized. A density shift experiment coupled with a marker frequency analysis shows that DNA synthesized at 45 C is highly enriched in the markers situated at the end of the chromosome. Transforming DNA extracted from a culture which has been incubated at 45 C exhibits the relative transforming efficiency for origin and terminus markers characteristic of completed chromosomes. After a shift back from 45 C to 30 C, reinitiation appears to occur always in the same region of the bacterial chromosome; in addition, replication as well as cell division is synchronized. PMID- 4196240 TI - Acid-base titration of streptococci and the physical states of intracellular ions. AB - Acid titrations of intact and butanol-treated cells of Streptococcus faecalis revealed that nearly all of the intracellular K(+) ions could diffuse into the suspending medium in association with small anions, including ribonucleic acid breakdown products, when the cell membrane was damaged. In contrast, nearly all of the intracellular Mg(2+) ions appeared to be firmly bound to stable internal cell components but could be displaced reversibly by hydronium ions. The cell membrane acted as a barrier to ion movements, and Mg(2+) displacement from intact cells required more acid conditions, by as much as 2.5 pH units, than did displacement from butanol-damaged cells. Some 15 to 20% of the cell magnesium appeared to be associated with surface structures in that it could be removed at pH 7 with ethylenediaminetetraacetic acid or displaced by Co(2+), Ni(2+), Sr(2+), or La(3+). Magnesium could be displaced from isolated cell walls and membranes by hydronium ions in the pH range from 5 to 3, over which carboxyl groups were titrated. Displacement of magnesium from ribosomes also took place between pH 5 and 3, but it was more difficult to identify the magnesium-releasing groups because both protein carboxyl groups and purine and pyrimidine ring nitrogens can become protonated in this pH range. Isolated protoplast membranes remained structurally intact when completely depleted of magnesium. Furthermore, protoplasts isolated from intact cells were found to have greatly enhanced resistance to osmotic shock in acid media, even when solute loss was not extensive. Osmotic resistance was lost when the protoplasts were again placed in neutral media, and this reversibility suggested that acidification caused changes in the physical properties of membranes as well as solute leakage from cells. PMID- 4196241 TI - Macromolecular syntheses during germination and outgrowth of Bacillus subtilis spores. AB - Alanine and glucose used jointly are known to be necessary and sufficient for spore germination in Bacillus subtilis 168. By testing them separately, we have verified that alanine provokes optimal phase-darkening of the spores but inhibits macromolecular syntheses, while glucose is specifically needed for initiating those syntheses. By using them in succession we obtained evidence suggesting that: (i) sporal modifications which lead to phase-darkening must occur before macromolecular synthesis can start; (ii) the amino acid pool, on which the early protein synthesis is solely dependent, expands during incubation in alanine which allows degradative but prevents synthetic activities; and (iii) progression of degradations in alanine not promptly followed by syntheses in glucose produce a metabolic imbalance in the germinating spore. A sharp transition in the origin of building blocks was shown by using a tryptophan-defective mutant. At first the synthesis of proteins depended on pre-existing amino acids from turnover of sporal material since it occurred in the absence of any exogenous amino acid and its rate remained unaltered by supplying either all amino acids except tryptophan or tryptophan alone. Eventually, protein synthesis became dependent strictly on exogenous tryptophan and strongly on the supply of several other amino acids, not required later during vegetative growth. Clearly, by the start of outgrowth, all building blocks must be provided either by endogenous de novo synthesis or by exogenous supply. PMID- 4196242 TI - Inactivation of aspartic transcarbamylase in sporulating Bacillus subtilis: demonstration of a requirement for metabolic energy. AB - The aspartic transcarbamylase (ATCase) activity of Bacillus subtilis cells disappears rapidly from stationary-phase cells prior to sporulation. ATCase activity does not appear in the culture fluid during the stationary phase; hence the enzyme appears to be inactivated in the cells. The enzyme is inactivated normally in two different mutants lacking proteases; the activity is very stable in crude extracts of cells or in the culture fluid. These results suggest that ATCase is not inactivated by the general proteolysis that occurs in sporulating bacteria. The inactivation of ATCase can be completely inhibited after it has begun by oxygen starvation or addition of fluoroacetate. Inhibitors of oxidative phosphorylation and electron transport also interrupt the inactivation of ATCase. The inactivation of ATCase is very slow in two mutant strains that are deficient in enzymes of tricarboxylic acid cycle. Addition of gluconate to stationary cultures of the mutant strains, which is known to restore depleted adenosine 5' triphosphate pools in these bacteria, also restores inactivation of ATCase. These experiments support the conclusion that the generation of metabolic energy is necessary for the inactivation of ATCase in stationary cells. ATCase activity is stable in growing cells in which ATCase synthesis is repressed by addition of uracil; the enzyme is inactivated normally, however, when such cells cease growing. PMID- 4196243 TI - Penicillin-binding component of Bacillus cereus. AB - (14)C-penicillin is irreversibly bound by Bacillus cereus 569. Incubation of penicillin-treated cells in a cell wall digestion medium results in solubilization of approximately 60% of the irreversibly bound lable. The extent of the solubilization is the same when cells are prepared by either a cold or 37 C treatment procedure. However, spheroplasts prepared by the cold treatment are leaky. When the resulting spheroplasts are incubated in supplemented medium, reduced rates and levels of penicillinase synthesis, relative to induced whole cell controls, are observed. Spheroplasts from both cold and 37 C prepared cells exhibit this phenomena, although the spheroplasts from 37 C prepared cells synthesized approximately sixfold higher levels of penicillinase. The size distribution of the label solubilized during the preparation of spheroplasts was examined by using Bio Gel P-150 columns. Although no label appeared in the exclusion volume fractions when the cell wall digest of the 37 C treated cells was chromatographed, approximately 10% of the label from cold-treated cells did appear. These results suggest that the presence of irreversibly bound penicillin is required for the synthesis of induced levels of penicillinase and that the irreversibly bound penicillin can be solubilized as a labile complex with material which is excluded from BioGel P-150. It may be concluded that the penicillin-binding lipoprotein complex which has been previously observed is the penicillin-specific binding site. However, the location of this complex in relation to the cell membrane could not be determined. PMID- 4196244 TI - Induction of superoxide dismutase by molecular oxygen. AB - Oxygen induces superoxide dismutase in Streptococcus faecalis and in Escherichia coli B. S. faecalis grown under 20 atm of O(2) had 16 times more of this enzyme than did anaerobically grown cells. In the case of E. coli, changing the conditions of growth from anaerobic to 5 atm of O(2) caused a 25-fold increase in the level of superoxide dismutase. Induction of this enzyme was a response to O(2) rather than to pressure, since 20 atm of N(2) was without effect. Induction of superoxide dismutase was a rapid process, and half of the maximal level was reached within 90 min after N(2)-grown cells of S. faecalis were exposed to 20 atm of O(2) at 37 C. S. faecalis did not contain perceptible levels of catalase under any of the growth conditions investigated by Stanier, Doudoroff, and Adelberg (23), and the concentration of catalase in E. coli was not affected by the presence of O(2) during growth. S. faecalis, which had been grown under 100% O(2) and which therefore contained an elevated level of superoxide dismutase, was more resistant of 46 atm of O(2) than were cells which had been grown under N(2). E. coli grown under N(2) contained as much superoxide dismutase as did S. faecalis grown under 1 atm of O(2). The E. coli which had been grown under N(2) was as resistant to the deleterious effects of 50 atm of O(2) as was S. faecalis which had been grown under 1 atm of O(2). These results are consistent with the proposal that the peroxide radical is an important agent of the toxicity of oxygen and that superoxide dismutase may be a component of the systems which have been evolved to deal with this potential toxicity. PMID- 4196245 TI - Association of many regions of the Bacillus subtilis chromosome with the cell membrane. AB - Unsheared lysates of Bacillus subtilis 168T(-) containing uniformly labeled deoxyribonucleic acid (DNA) were exposed to varying doses of gamma rays to introduce double-strand scissions in the chromosome. From an estimate of the number-average molecular weight and the amount of DNA bound to membrane after irradiation, about 70 to 90 regions of the bacterial chromosome were detected in membrane fractions. Since this number was independent of the molecular weight of the DNA (i.e., the extent of fragmentation of the chromosome), it is thought to represent an upper limit in the number of membrane-binding sites per chromosome. PMID- 4196246 TI - Intergeneric complementation of anthranilate synthase subunits. AB - Partially purified subunits of anthranilate synthase were prepared from Bacillus subtilis and Pseudomonas aeruginosa. The large component from B. subtilis (I(B)) complements well with the small component from P. aeruginosa (II(P)) to reconstitute a glutamine-reactive anthranilate synthase. This interaction can be demonstrated with crude extracts from a B. subtilis trpX mutant and a P. aeruginosa trpA mutant. Complementation was also observed with the large component from P. aeruginosa (I(P)) and the small subunit from B. subtilis (II(B)). At saturation the heterologous complex I(B)II(P) has 93% of the activity of the homologous complex I(B)II(B), whereas the hybrid I(P)II(B) is only 22% as active as the homologous complex I(P)II(P). PMID- 4196247 TI - Effects of mutational loss of specific intracellular proteases on the sporulation of Bacillus subtilis. AB - Two protease-deficient mutants of Bacillus subtilis 168 (Trp(-)) were isolated and compared with the parental strain with respect to production of intracellular proteases and sporulation. A mutant lacking the metal-requiring "neutral" protease intracellularly sporulated as well as the parental strain. A second mutant, deficient in an as yet uncharacterized intracellular protease, failed to sporulate normally. It is proposed that this new protease is also involved in intracellular protein turnover. PMID- 4196248 TI - Characterization of the polydisperse closed circular deoxyribonucleic acid molecules of Bacillus megaterium. AB - The polydisperse circular deoxyribonucleic acid (DNA) molecules which comprise up to 30% of the total extractable DNA of Bacillus megaterium strain 216 have been purified and partially characterized. Banding in cesium chlorideethidium bromide by "gradient relaxation" in a fixed-angle rotor provided good resolution of circular and chromosomal DNAs for preparative separations. Renaturation studies on purified circular DNA failed to reveal a rapidly renaturing fraction, and DNA DNA hybridization studies indicated that the majority of the chromosomal nucleotide sequences are represented in the heterogeneous-size population of circular molecules. It is concluded that the circular DNA of B. megaterium does not represent typical bacterial plasmid DNA. The possibility that the circular DNA molecules are the result of the expression of a defective bacteriophage is discussed. PMID- 4196249 TI - Role of intestinal microflora in the metabolism of guanidinosuccinic acid. AB - Among a variety of bacteria isolated from the gastrointestinal tracts of rats and humans, only streptococci of group N are capable of degrading guanidinosuccinic acid added to their culture medium. The urinary excretion of guanidinosuccinic acid by germfree rats is greater than that of conventional rats. The excretion of this compound by gnotobiotic rats correlates with the capacity of their intestinal microflora to degrade guanidinosuccinic acid in culture. Thus, guanidinosuccinic acid excretion is low in rats infected exclusively with Streptococcus faecalis, and the excretion is not altered when germfree rats are infected with an organism unable to degrade guanidinosuccinic acid (Lactobacillus). These findings suggest that the intestinal microflora, particularly Streptococcus, play a role in the metabolism of guanidinosuccinic acid by the host. PMID- 4196250 TI - Chorismate mutase from Streptomyces aureofaciens: a heat-stable enzyme. AB - Chorismate mutase from Streptomyces aureofaciens was purified 12-fold. This enzyme preparation did not show any activity when tested for anthranilate synthetase, prephenate dehydrogenase, or prephenate dehydratase. The catalytic activity of chorismate mutase has a broad optimum between pH 7 and 8. The initial velocity data followed regular Michaelis-Menten kinetics with a K(m) of 5.3 x 10( 4) M, and the molecular weight of the enzyme was determined by sucrose gradient centrifugation to be 50,000. Heat inactivation of chorismate mutase, which occurs above temperatures of 60 C, is reversible. The enzyme activity can be restored even when chorismate mutase is treated at the temperature of a boiling-water bath for 15 min. Heat-denatured and renatured enzymes showed the same Michaelis constant and the same molecular weight as the native enzyme. l-Phenylalanine, l tyrosine, l-tryptophan, and metabolites of the aromatic amino acid pathway were tested as potential modifiers of chorismate mutase activity. The activity of the enzyme was inhibited by none of these substances. Chorismate mutase of S. aureofaciens was not repressed in cells grown in minimal medium supplemented with l-phenylalanine, l-tyrosine, or l-tryptophan. PMID- 4196252 TI - Role of reduced exogenous organic compounds in the physiology of the blue-green bacteria (algae): photoheterotrophic growth of a "heterotrophic" blue-green bacterium. AB - Nostoc sp. (strain Mac) was shown to be capable of using glucose, fructose, or sucrose as a sole source of carbon and energy in the dark. In the light in the absence of exogenously supplied CO(2), this strain exhibited a more versatile metabolism. In addition to the three sugars above, glycerol and acetate served as sole sources of carbon. This photoheterotrophic growth in the absence of exogenously supplied CO(2) appears to involve O(2)-evolving photosynthesis. The action spectrum for photoheterotrophic growth on acetate closely resembles the action spectrum for photosynthesis. The physiology of photoheterotrophic growth was further investigated through determinations of stable carbon isotope ratios and measurements of gas exchanges. These investigations suggest that respired CO(2) from substrate oxidation is assimilated by the photosynthetic machinery. PMID- 4196251 TI - Escherichia coli mutants permissive for T4 bacteriophage with deletion in e gene (phage lysozyme). AB - Escherichia coli mutants have been isolated that are permissive for the infection by T4 phage with deletion in the cistron for the phage lysozyme, the e gene. Some, but not all, of these mutants are simultaneously permissive for the infection by T4 phage defective in the t gene, the product of which has also been implicated in the release of progeny phages. Most of these mutants shared the following properties: temperature sensitivity in growth and cell division, increased sensitivity towards a number of unrelated antibiotics and colicins, and increased sensitivity towards anionic detergents (sodium dodecyl sulfate and sodium deoxycholate). The possible biochemical basis for these phenotypes is discussed. PMID- 4196253 TI - Role of reduced exogenous organic compounds in the physiology of the blue-green bacteria (algae): photoheterotrophic growth of an "autotrophic" blue-green bacterium. AB - The unicellular blue-green bacterium Agmenellum quadruplicatum strain BG-1 was found to be capable of rapid photoheterotrophic growth but unable to grow in the dark on a variety of reduced organic substrates. The generation time on glycerol was 12 h, and on CO(2), 3 h. Glycerol carbon was converted into cellular carbon with a very high efficiency. This high efficiency of carbon conversion, the action spectrum for growth on glycerol, cell pigmentation, gas exchange measurements, and immediate ability of photoheterotrophically grown cells to evolve O(2) (upon the addition of CO(2)) suggest the involvement of both photosystems I and II of photosynthesis during photoheterotrophic growth. PMID- 4196254 TI - Deoxyribonucleic acid-membrane complexes in the Bacillus subtilis transformation system. AB - The fate of transforming deoxyribonucleic acid (DNA) in Bacillus subtilis was studied by isolating the DNA-membrane complex on Renografin gradients. Soon after uptake, transforming DNA binds to the cell membrane and displays a greater resistance to shear than the recipient genome-membrane complex. Ten minutes after uptake, a portion of the donor DNA is released from the membrane. Most of the released donor radioactivity represents unintegrated, biologically inactive DNA. Recombinant or integrated DNA is enriched 1.5- to 1.7-fold in the membrane. This enrichment last at least 30 min after termination of DNA uptake, and probably much longer. The data suggest that transforming DNA may be integrated into the recipient genome on, or close to, the cell membrane. PMID- 4196255 TI - Structural difference between walls from hemispherical caps and partial septa of Bacillus subtilis. AB - Walls from partial septa of Bacillus subtilis bacteria are more sensitive than end walls to digestion by B. subtilis autolytic amidase. This result indicates that, after synthesis, B. subtilis septal walls are modified to an amidase resistant form. PMID- 4196256 TI - Mutant of Bacillus subtilis with a temperature-sensitive autolytic amidase. AB - A procedure incorporating a petri plate assay for autolysins has been developed for the systematic isolation of mutants with a temperature-sensitive autolytic amidase. We suggest maa as the name for the gene for this enzyme. One such mutant has been characterized as having a heat-sensitive amidase in a variety of studies with both crude autolysin preparations and purified amidase solutions. PMID- 4196257 TI - Micrococcus lysodeikticus bacterial walls as a substrate specific for the autolytic glycosidase of Bacillus subtilis. AB - The Bacillus subtilis 168 autolytic glycosidase degrades Micrococcus lysodeikticus cells or cell walls, whereas the B. subtilis autolytic amidase does not. The criteria used to establish this fact included: the determination of chemical bonds broken, heat-inactivated kinetics, pH dependence curves, and the physical separation of glycosidase from amidase. The physical separation involved LiCl elution from two different ion-exchange materials, walls from B. subtilis 168 strain betaAO, and walls from mutant strain betaA173 derived from strain betaAO. No evidence was obtained for B. subtilis vegetative bacteria making any more autolysins than one autolytic amidase and one autolytic glycosidase. PMID- 4196258 TI - Large surface blebs on Escherichia coli heated to inactivating temperatures. AB - Large surface blebs were observed with phase-contrast optics on Escherichia coli B/r and B(s-1) heated to temperatures at which colony-forming ability was lost. Characterization of such blebs was consistent with the view that they were formed by a physical process and were bounded by the outer membrane of the cell. A hypothesis for thermal inactivation of E. coli is presented that places membrane damage near the primary lethal event. PMID- 4196259 TI - Minicells of Bacillus subtilis. AB - After nitrosoguanidine (N-methyl-N'-nitro-N-nitrosoguanidine) mutagenesis, two Bacillus subtilis mutants (div IV-A1 and div IV-B1) were isolated that are defective in the location of division site along cell length. Both mutations were transferred into strain CU403 by transformation, and their properties were studied in the CU403 genetic background. Location of divisions in close proximity to cell pole regions in both mutants results in minicell production. Purified minicells contain a ratio of ribonucleic acid to protein comparable to that found in the parent cells. Autoradiographs of (3)H-thymine incorporation into deoxyribonucleic acid (DNA), thymine-2-(14)C incorporation into DNA, electron micrographs, and chemical analyses for DNA all fail to demonstrate DNA in the minicells. Minicells produced by both mutants are highly motile, an indication of functional energy metabolism. Electron micrographs reveal that minicells are produced by a structurally normal division mechanism and that minicells contain a normal cell surface. The div IV-A1 mutation has been mapped by PBS1 transduction linked to ura. The div IV-B1 mutation is closely linked to pheA by both PBS1 transduction and by co-transformation. PMID- 4196260 TI - Stimulation of cell division by croton oil in blue-green bacteria. AB - The potent tumor-promoting agent croton oil, which has been shown previously to be strongly mitogenic in mammalian cells, stimulates cell division in snake mutants of the blue-green bacterium Agmenellum quadruplicatum. PMID- 4196261 TI - Influence of magnesium ions on porosity of the Bacillus megaterium cell wall and membrane. AB - The presence of magnesium chloride (0.01 M) caused a relatively small but significant reduction in the equivalent porosity of the protoplast membrane, but not in that of the cell wall, in intact Bacillus megaterium cells. PMID- 4196262 TI - Prolactin response to thyrotropin releasing hormone in normal subjects. PMID- 4196263 TI - Changes in iodine metabolism and thyroglobulin structure in metastatic follicular carcinoma of the thyroid with hyperthyroidism. PMID- 4196264 TI - L-dopa suppression of TRH-stimulated prolactin release in man. PMID- 4196265 TI - Plasma growth hormone response to thyrotropin-releasing hormone in patients with active acromegaly. PMID- 4196266 TI - The structure of the medial geniculate nucleus (MGN): a cyto- and myeloarchitectonic study in the squirrel monkey. PMID- 4196267 TI - Control of responding by location of auditory stimuli: role of differential and non-differential reinforcement. AB - Sound was presented to monkeys through one of two loudspeakers, each adjacent to a response key. A response on the key adjacent to the sound source was reinforced (correct response). A response on the other key produced a timeout (incorrect response). Under these conditions, over 90% of responses were correct within one or two sessions. When the procedure was changed so that a response on either key was reinforced independently of which speaker was sounding, similar control by location developed within one or two sessions. When conditions were modified by moving the keys away from the immediate vicinity of the speakers, the animals required about 20 sessions to reach a stable level of greater than 90% correct responses under differential reinforcement conditions. No control by location developed under nondifferential reinforcement conditions. PMID- 4196268 TI - Behavioral assessment of pain detection and tolerance in monkeys. AB - Cebus albifrons monkeys received electrical stimulation of the hindlimbs over a wide range of intensities. On trials signalled by a blue light, the animals were permitted to escape shock by pressing a disc, or shock was terminated after 8 sec (free escape). Escape force (disc pressure) was found to increase as stimulation intensity increased well beyond escape threshold, while shock duration curves reached plateau at the mid-range of intensities. The shock duration curves generated by free escape responses should be comparable to pain detection functions obtained by similar operations in humans, and the curves were stable over months of testing, as is generally found in pain-detection studies. On trials signalled by a red light, the animals received intense tail shock immediately after escape responses (punished escape), or, if they endured leg shock for 8 sec without escaping, then they could avoid tail shock with a panel press. The shock duration curves generated by punished escape responses should be comparable to pain tolerance functions as defined for human subjects, and the escape thresholds were considerably higher on red-light trials. As in human studies, the tolerance curves were not stable over repeated testing sessions, and some feature of the paradigm forced a progression toward extremely high levels of tolerance. PMID- 4196269 TI - Operantly conditioned patterns on precentral unit activity and correlated responses in adjacent cells and contralateral muscles. PMID- 4196270 TI - Hippocampal influence on unit activity of hypothalamus, preoptic region, and basal forebrain in awake, stting squirrel monkeys. PMID- 4196272 TI - Peripheral neural determinants of temperature discrimination in man: a correlative study of responses to cooling skin. PMID- 4196271 TI - "Cold" fiber population innervating palmar and digital skin of the monkey: responses to cooling pulses. PMID- 4196273 TI - [Methods for determining the proteolytic activity of rennet preparations]. PMID- 4196274 TI - [Proteolytic degradation of milk proteins by bacteria. 2. The action of psychrophilic and lactic acid producing bacteria on the proteins in milk]. PMID- 4196275 TI - Survival of common bacteria in liquid culture under carbon dioxide at high temperatures. PMID- 4196276 TI - Morphology of receptor innervation of spinal ganglia. PMID- 4196277 TI - A Rhesus incompatible baby. PMID- 4196278 TI - Estrogen formation by the isolated perfused rhesus monkey brain. AB - Perfusion of two isolated brains from immature male rhesus monkeys with [(3)H]androstenedione resulted in the identification of free and conjugated [(3)H]estrone and free [(3)H]estradiol from the perfusates. In the dissected cerebral tissues, estrogens were recovered only from the hypothalamus and limbic system. The production of estrogens from androstenedione during the 40-minute perfusions in these two experiments totaled 1.58 and 2.83 nanograms. PMID- 4196279 TI - The proximal negative response of the primate retina. PMID- 4196280 TI - [Diagnostic significance of some functional reactions of the facial skin in brain tumors]. PMID- 4196281 TI - Thyroidectomy cells and their response to thyrotrophin releasing hormone (TRH) in the rat. PMID- 4196282 TI - Serum lysozyme in pulmonary tuberculosis. PMID- 4196283 TI - Hypothalamic hypothyroidism: diminished thyroidal response to thyrotropin releasing hormone. PMID- 4196284 TI - Bullous retinal detachment. An unusual manifestation of idiopathic central serous choroidopathy. PMID- 4196285 TI - Cyclopia. PMID- 4196286 TI - Pilocarpine uptake by pigmented uveal tissue. PMID- 4196287 TI - Experimental infections with African trypanosomes. V. Preliminary parasitological, clinical, hematological, serological, and pathological observations in rhesus monkeys infected with Trypanosoma rhodesiense. PMID- 4196288 TI - Studies on the immunization of monkeys against dengue. I. Protection derived from single and sequential virus infections. PMID- 4196289 TI - Studies on the immunization of monkeys against dengue. II. Protection following inoculation of combinations of viruses. PMID- 4196290 TI - Vascular changes in the anterior uvea of the rabbit produced by prostaglandins. PMID- 4196291 TI - Expandable silicone implants for scleral buckling. I. Introduction of a new concept. PMID- 4196292 TI - Mitochondrial DNA from Drosophila melanogaster. PMID- 4196293 TI - Postoperative wound infection in colonic and rectal surgery. PMID- 4196294 TI - Long-term anticoagulant treatment after myocardial infarction. A review. PMID- 4196296 TI - [In vivo metabolism of 3-3'-4-5 isoleucine-C 14 in Aspergillus niger Van Tieghem]. PMID- 4196295 TI - [A familial case of dysgenesis of the anterior segment of the eye]. PMID- 4196297 TI - [Properties of an incompatibility system in Podospora anserina fungus and value of this system for the study of incompatibility]. PMID- 4196298 TI - [Ultrastructure and systematic affinities of Microrhopalodina inflats, symbiotic flagellate of the yellow neck termite, Calotermes flavicollis]. PMID- 4196299 TI - [Plasmatic concentrations of prolactin and thyrostimulating hormone during ewe milking: comparative study with effects of TRF]. PMID- 4196300 TI - [Effect of L-Dopa on the secretion of prolactin in eels]. PMID- 4196301 TI - [Concentrations of 17 estradiol, estrone and testosterone in the spermatic vein in man]. PMID- 4196302 TI - [In vivo study of cardiac rhythm in Schistocerca gregaria]. PMID- 4196303 TI - [New anion exchangers--piperidine N-ethylcellulose, di isopropylaminoethylcellulose--for protein chromatography]. PMID- 4196304 TI - [Identification in bovine thyroglobulin of an iodinated dipeptide, tetraiodinated tyrosyltyrosine]. PMID- 4196305 TI - [Partial purification and properties of a deoxyribonuclease from Chlamydomonas reinhardtii]. PMID- 4196306 TI - [Effect of different phospholipases on glomerular basement membranes of the rat kidney]. PMID- 4196307 TI - [Transfer of antigraft immunity in the earthworm, Eisenia foetida Sav]. PMID- 4196308 TI - Acute alcoholic fatty liver in the Rhesus monkey. PMID- 4196309 TI - Renal function in chronic intravascular haemolysis associated with prosthetic cardiac valves. PMID- 4196310 TI - Peptide composition of human plasma apolipoproteins A, B and C. PMID- 4196311 TI - [Interactions between lipoproteins and immunoglobulins]. PMID- 4196312 TI - [Abnormal lipoproteins in human and experimental biliary obstruction]. PMID- 4196314 TI - Dietetics reaches out. PMID- 4196313 TI - [Catamnestic studies in 3-sec spike and wave carriers]. PMID- 4196315 TI - Immunospecific purification of human anti-IgM serum utilizing cord serum immunoadsorbent. PMID- 4196316 TI - Principles of viable preservation of parasitic Protozoa. PMID- 4196317 TI - Babesia canis: the life cycle and laboratory maintenance in its arthropod and mammalian hosts. PMID- 4196318 TI - Babesia argentina: the infectivity and immunogenicity of irradiated blood parasites for splenectomized calves. PMID- 4196319 TI - Learning in monkeys after combined lesions in frontal and anterior temporal lobes. PMID- 4196320 TI - Matching within and between sense modalities in the monkey (Macaca mulatta). PMID- 4196321 TI - [Nutripump for continuous slow enteral feeding]. PMID- 4196322 TI - Dietary effect on liver fatty acid synthetase. PMID- 4196323 TI - [Detection of sources and routes of infection with Pseudomonas aeruginosa in a urologic department]. PMID- 4196324 TI - Osmotic opening of the blood-brain barrier in the monkey without associated neurological deficits. AB - Hypertonic urea or lactamide solutions osmotically open the blood-brain barrier in the monkey without producing gross neurological deficits if the blood supply to the brain is not compromised. The brain is perfused via the left lingual artery when the external and common carotid arteries are clamped temporarily. Hypertonic perfusion, which opens the barrier by opening tight junctions between cerebrovascular endothelial cells, can thus be used to study barrier function and brain pharmacology. PMID- 4196325 TI - Gas-filled structures providing buoyancy in photosynthetic organisms. PMID- 4196326 TI - [Polyploid characteristics of the micronuclei in infusorians]. PMID- 4196327 TI - [Autoradiographic study of the duration of spermatogenesis stages in the cricket]. PMID- 4196328 TI - [DNA content in the macro- and micro-nuclei of Colpoda steini before and after division in reproduction cysts]. PMID- 4196329 TI - On the histogenesis of the cells in fracture callus. Electron microscopic autoradiographic observations in parabiotic rats and studies on labeled monocytes. PMID- 4196331 TI - The development of TSH producing pituitary tumours in the mouse. PMID- 4196330 TI - Catecholamine storage in liver metastases of a malignant carotid body tumour. A biochemical and morphological study. PMID- 4196333 TI - A method of central venous alimentation catheter placement for use in small infants. PMID- 4196332 TI - Interactions between modified phage T4 particles and spheroplasts. PMID- 4196334 TI - Effect of nitrate, ammonia and nitrogen starvation on the regulation of nitrate reductase in Cyanidium caldarium. PMID- 4196335 TI - A comparison of pre-operative and primary radiotherapy in the treatment of carcinoma of the hypopharynx. PMID- 4196336 TI - Thoracic enteric cysts and diverticulae. PMID- 4196337 TI - Massive haemorrhage in elephantiasis neurofibroma. PMID- 4196338 TI - Enzyme typing of malaria parasites. AB - Analysis of various isolates of Plasmodium falciparum from East and West Africa and from South-east Asia showed that some of the parasite enzymes can exist in more than one electrophoretic form. At least one form of each enzyme was common to parasites from all three regions. The enzyme forms could be used to differentiate morphologically indistinguishable samples of P. falciparum. PMID- 4196339 TI - Anthrax. PMID- 4196340 TI - Experimental infection of animals with influenzavirus types A and B. AB - The knowledge that domestic cats were susceptible to infection with freshly isolated A/Hong Kong/68 influenzavirus led to studies on the susceptibility of some other animal species to this virus, as well as to studies on the ability of egg-passaged Hong Kong virus and an Asian virus to infect cats. The ability of a recent isolate of influenzavirus B to infect these animals was also studied. Macaca radiata monkeys could be infected with fresh isolates of A/Hong Kong virus by intranasal instillation or by contact with infected animals. They could also be infected with influenzavirus B by intranasal challenge, but contact transmission was not demonstrated. Mongrel dogs were found to be susceptible to A/Hong Kong/68 virus by intranasal instillation, but not to type B virus. Domestic cats could be infected with A/Hong Kong/68 virus passaged 6 times in eggs. They were also susceptible to infection with an established laboratory strain of Asian virus. Cats could be infected with influenzavirus B either by intranasal challenge or by contact with infected animals. In no case was clinical illness found following infection, but the infected animals shed virus from the throat and developed haemagglutination inhibiting antibodies. PMID- 4196341 TI - Temperature-dependent transition in L-histidine ammonia-lyase. PMID- 4196342 TI - Fractionation of chromatin components. PMID- 4196343 TI - Various blood glucose values in the rat. PMID- 4196344 TI - Preparation of 125I-labelled thyrotrophin-releasing hormone. PMID- 4196345 TI - Falsely high fluorescence in cortisol determinations due to the carbamazepine. PMID- 4196346 TI - Different amounts of insulin secretion following an equal total decrease of blood glucose as an indication of possible extrapancreatic activities of different sulfonylurea drugs. PMID- 4196347 TI - The microbiologic determination of serum folic acid activity. I. Study of the assay system. PMID- 4196348 TI - A trial of haemagglutination, circumoval precipitin and gel diffusion tests in hookworm infection. PMID- 4196349 TI - Effect of cortisone on immunologic cardiac injury in albino rats. PMID- 4196351 TI - Measurement of the infectivity of Trypanosoma cruzi in faeces of Rhodnius by comparison of dose-response curves. PMID- 4196350 TI - The immune response of a cyprinid fish to infections of the acanthocephalan Pomphorhynchus laevis. PMID- 4196352 TI - [Experimental study of electron beam collimation with an adjustable lead collimator]. PMID- 4196353 TI - [Reduction of the dose to the skin in contact with the treatment table for high energy X ray beams]. PMID- 4196354 TI - [1000 cases of pharyngeal cancer treated with radiocobalt. A 5 year follow-up study]. PMID- 4196355 TI - United States-Japan cooperative drug abuse study. PMID- 4196356 TI - Function of the alpha cell in diabetic ketoacidosis. PMID- 4196357 TI - [Study of an abnormal lipoprotein (LP-X) associated with cholestasis]. PMID- 4196358 TI - Auditory processing of biologically significant sounds. PMID- 4196359 TI - Fine structure of the chloroplast membranes of Euglena gracilis as revealed by freeze-cleaving and deep-etching techniques. PMID- 4196360 TI - Effects of chlordiazepoxide upon successive red-green discrimination responses in Japanese monkeys, Macaca fuscata. PMID- 4196361 TI - [The behavior of immunoglobulins and other plasma proteins in chronic myeloid leukemia studied by immunological methods]. PMID- 4196362 TI - [Hypophosphatemia, paresthesia and intense muscular weakness in an undernourished patient under parenteral feeding. Report of a case]. PMID- 4196363 TI - The handling of contaminated abdominal wounds. PMID- 4196364 TI - Ultrastructure and ion distribution of the intestinal cell during experimental vitamin-D deficiency rickets in rats. PMID- 4196365 TI - [Regeneration and cell proliferation of the thymus after cyclophosphamide]. PMID- 4196366 TI - [Role of the mesenchymal cells in the development of arteriosclerosis]. PMID- 4196367 TI - [Facts provided by the ultrastructural study of two cases of malacoplakia]. PMID- 4196368 TI - [Electron microscopy studies on the behavior of smooth muscle cells in the arterial wall under various experimental conditions]. PMID- 4196369 TI - Fatal necrotizing angiitis after sulfadimethoxine therapy presenting as anaphylactoid purpura. PMID- 4196370 TI - Regional variations in mouse skin: quantitation of epidermal compartments in two different body sites. PMID- 4196371 TI - [Number of nuclei in isolated human myocardial cells]. PMID- 4196372 TI - [Development of congophilic stellate deposits in experimental amyloidosis of mice produced by transplanting viable spleen cells]. PMID- 4196373 TI - [Polymorphous giant nuclei in the epithelium of human seminal vesicles]. PMID- 4196374 TI - Puzzling structures in the renal glomeruli of 13 patients. An electron microscopical study. PMID- 4196375 TI - Procedures in radiation therapy dosimetry with 5 to 50 MeV electrons and roentgen and gamma rays with maximum photon energies between 1 and 50 MeV. PMID- 4196376 TI - Electroanesthesia studies: cerebral blood flow and oxygen utilization during electroanesthesia in the rhesus. PMID- 4196377 TI - Genealogical mating activity in free-ranging groups of rhesus monkeys (Macaca mulatta) on Cayo Santiago. PMID- 4196378 TI - In vitro synthesis of DNA spontaneously released by bacteria or frog auricles. PMID- 4196380 TI - [Seasonal changes in Sertoli and Leydig cell activity in the testis of the golden hamster. Karyometric study]. PMID- 4196379 TI - [Maturation and ovulation in vitro of rainbow trout Salmo gairdnerii ovocytes]. PMID- 4196381 TI - [Sensitivity of cat and rabbit pulmonary stretch receptors to changes in CO 2 pressure]. PMID- 4196382 TI - [Effects of 6-hydroxydopamine micro-injections into the nigro-striated system on learning in albino rats]. PMID- 4196383 TI - [Neurohistological study of reticular cells in the mammalian hypothalamus]. PMID- 4196384 TI - [Demonstration of collagen in the extracellular material of axial organs of young chick embryos]. PMID- 4196385 TI - [In vitro cultivation of pieces of young reptile embryo body; experiences of ablation and grafting of somites]. PMID- 4196386 TI - [Optical rotary dispersion of DNP and RNP complexes and acid proteins from the cell nucleus]. PMID- 4196388 TI - [Introduction to multidisciplinary treatment of the human species as a biological entity]. PMID- 4196387 TI - [Preparation and properties of and chain globins of human hemoglobin]. PMID- 4196389 TI - [Structural alterations of the white muscle of the carp (Cyprinus carpio L.) during prolonged fasting]. PMID- 4196390 TI - [Origin of the fast activity of the chronic electromyogram of the intestinal wall]. PMID- 4196391 TI - [Attempt at induction of "stable behavior" with d-amphetamine in emotive and non emotive rats]. PMID- 4196392 TI - [Renal metabolism of 18-hydroxycorticosterone]. PMID- 4196393 TI - [Characterization of a testosterone metabolite in the urine of male guinea pigs: 5 beta-androstane-3 alpha-ol 7-17 dione]. PMID- 4196394 TI - [Early secretion of testosterone by embryonic mouse testis]. PMID- 4196395 TI - [Selective incorporation of GABA H3 into the neurohypophysis of the teleostean fish Gasterosteus aculeatus L. Autoradiographic study]. PMID- 4196396 TI - [Histamine fixation by normal human serum using a Sephadex chromatography technic]. PMID- 4196397 TI - [Modulation of adenyl cyclase activity in the rat heart after colza oil ingestion]. PMID- 4196398 TI - [Demonstration of a cycle, associated with shedding of the coat cycle, for lipids and hydrocarbons in crayfish blood]. PMID- 4196400 TI - [Visualisation of a network phenomenon between "Australia" antigen and anti-Au antibodies (in vitro and in vivo)]. PMID- 4196399 TI - [Influence of gonadotropic hormones on radioactive testosterone synthesis Na 14C acetate by cultivated embryonic mouse testis in vitro]. PMID- 4196401 TI - [Effect of serum from a patient with myasthenia gravis on myoblastes and muscular ribbons of the rat cultured in vitro]. PMID- 4196402 TI - [Nature of antagonisms responsible for Mg++, Cd++ and Zn++ interaction in the growth of Aspergillus niger]. PMID- 4196403 TI - [Nucleolar and mitochondrial alterations and changes in deoxyribonucleic acid synthesis in chick fibroblasts cultivated in vitro with ethidium bromide]. PMID- 4196404 TI - [New data on the regulation of the estrus cycle by the corpus luteum in guinea pigs]. PMID- 4196405 TI - [Role of the cecal wall in the regulation of the amino acid blood level in rabbits]. PMID- 4196406 TI - [Effect of K + and Na + monovalent cations on the intracellular potential of ovocytes from Pleurodeles waltii Michah (urodele amphibian)]. PMID- 4196407 TI - [Insulin and glucagon perinatal hormonogenesis in rats]. PMID- 4196408 TI - [Obtaining specific immune serums of the hypothalamic factor (LH, FSH-RH) which stimulates the liberation of pituitary gonadotropins and the development of the radioimmunologic assay of this peptide]. PMID- 4196409 TI - [Feminizing effect of testosterone and androstenedione on the testis and Mullerian duct from chick embryo cultivated in vitro]. PMID- 4196410 TI - [Electrophysiologic study of the hydrodynamic receptor of the antenna of the lobster Palimurus vulgaris]. PMID- 4196411 TI - [Development of gonads transplanted in the axolotl limb, as a function of the sex of the host. Ovary]. PMID- 4196412 TI - [Organotypic culture of normal liver from newborn rats]. PMID- 4196413 TI - [Embryologic origin of thymus lymphocytes in bird embryos]. PMID- 4196414 TI - [The role of preliminary experience in elimination learning]. PMID- 4196415 TI - [Study of non Mendelian female sterility in Drosophila melanogaster. Hereditary transmission of the degree of efficacy of the reactor factor]. PMID- 4196416 TI - [Study of the contamination of Arenicola marina L. (polychaete, annelids) by cobalt 60]. PMID- 4196418 TI - [Demonstraction of a phospholipase A activity in Achlya bisexualis after culture on lecithin]. PMID- 4196417 TI - [X-ray diffraction study of a DNA with a low percentage of guanine plus cytosine bases]. PMID- 4196419 TI - [A mutant Escherichia coli with abnormalities in division and cellular morphology]. PMID- 4196420 TI - [Effect of an inhibitor of the immunogenic response on the development of tolerance to delta 9 tetrahydrocannabinol]. PMID- 4196421 TI - [Secretory differentiation of reticular cells in the hematopoietic organ of Locusta migratoria immunized against Bacillus thurigiensis. Electron microscopy study]. PMID- 4196422 TI - [Elimination by in vivo pulmonary lavage of inhaled plutonium oxide particles. Determination of the time for intervention]. PMID- 4196423 TI - Ophthalmic care in Greenland. PMID- 4196424 TI - The ocular inflammation produced following intravitreal injection of a stable L phase variant of Neisseria meningitidis. PMID- 4196426 TI - Cytotoxic effect of dimethylsulfoxide on the ultrastructure of cultured Rhesus kidney cells. PMID- 4196425 TI - Echovirus type 17 in the neonate. AB - An outbreak of echovirus type 17 in a neonatal nursery with recovery of virus from the stools of the seven affected infants and the cerebrospinal fluid of one is described. Intensive nursing care and supportive therapy prevented a possible fatal outcome in all instances. A further case in another community is described in which a 5-week-old child succumbed to his illness and echovirus type 17 was isolated from autopsy tissues - lung, liver, kidney and spleen. This child had presumably received poor home care. The suggestion is made that while echovirus type 17 is not frequently associated with adult disease, it may exhibit affinity for infant tissues. This is thought to be the first time that this virus has been associated with clinical disease in a neonatal nursery and also the first account of its recovery from postmortem tissues. PMID- 4196427 TI - Characteristics of the pituitary binding sites for thyrotropin releasing factor. PMID- 4196428 TI - Radioimmunoassay of rhesus monkey follicle stimulating hormone (RhFSH). PMID- 4196429 TI - Gonadal function and the biological and physicochemical properties of follicle stimulating hormone. PMID- 4196430 TI - Hyperthyroidism induced by thyrotropin-releasing hormone in mice. PMID- 4196432 TI - Grading of protein calorie malnutrition. PMID- 4196431 TI - Induced LH surges in the rhesus monkey: strength-duration characteristics of the estrogen stimulus. PMID- 4196433 TI - The kinetics of the killing of mouse tumour cells in vivo by immune responses. PMID- 4196434 TI - Genetic properties of substituted derivatives of N-methyl-4-aminoazobenzene in relation to azo-dye carcinogenesis. PMID- 4196435 TI - [Transitory cell antigens of rat liver. II. Effect of synthesis inhibitors of fetospecific serum proteins in normal young animals and after acute hepatic injury]. PMID- 4196436 TI - Cellular immunity to human urinary bladder carcinoma. I. Correlation to clinical stage and radiotherapy. PMID- 4196437 TI - Cellular immunity to human urinary bladder carcinoma. II. EEffect of surgery and preoperative irradiation. PMID- 4196438 TI - Induction of delayed-type sensitivity-like reactions in the eye by the injection of lymphokines. PMID- 4196439 TI - Prostaglandin synthesis, inhibition, and intraocular pressure. PMID- 4196440 TI - The effect of arterial PCO2 on inner-retinal oxygen availability in monkeys. PMID- 4196441 TI - The effect of arterial PCO2 on inner-retinal oxygen consumption rate in monkeys. PMID- 4196442 TI - Dome fracture of the talus. A report of ten cases. PMID- 4196443 TI - Treatment of defects of the ulna in children by establishing cross-union with the radius. PMID- 4196444 TI - [Surgery of mucosal diverticula of the duodenal window]. PMID- 4196445 TI - Activity of aminoglycoside antibiotics aganst Pseudomonas aeruginosa: specificity and site of calcium and magnesium antagonism. PMID- 4196446 TI - Immunology of Escherichia coli: K antigen and its relation to urinary-tract infection. PMID- 4196447 TI - Comparative activity of sisomicin against mycobacteria in vitro and against Mycobacterium tuberculosis in mice. PMID- 4196449 TI - Fetal-maternal plasma calcium relationships in rat and sheep. PMID- 4196450 TI - [Results of radiation therapy of cancer of the distal portion of the stomach]. PMID- 4196451 TI - A survey to assess potential human disease hazards along proposed sea level canal routes in Panama and Colombia. I. Introduction. PMID- 4196452 TI - A survey to assess potential human disease hazards along proposed sea level canal routes in Panama and Colombia. II. geography of proposed routes. PMID- 4196453 TI - Problems in interpreting tuberculin skin tests. When is a converter not a converter?: a review. PMID- 4196454 TI - Pyrimethamine-induced leukopenia and thrombocytopenia in a patient with malaria and tropical sprue: case report. PMID- 4196455 TI - Case for diagnosis: focal interstitial myocarditis. PMID- 4196456 TI - Building a new wing. PMID- 4196457 TI - The development of a MHCS role in race relations. PMID- 4196458 TI - Mental hygiene command consultation program at an army training center. PMID- 4196459 TI - Experience with drug abuse. PMID- 4196460 TI - A clinical evaluation of 81 heroin addicts in Vietnam. PMID- 4196461 TI - Neuroepidemiology. PMID- 4196462 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 26-1973. PMID- 4196463 TI - Effects of testosterone treatment in adulthood on sexual behaviour of female pseudohermaphrodite rhesus monkeys. PMID- 4196464 TI - Validity of the quadratic fitness function. PMID- 4196465 TI - Early results of Charnley-Muller total hip reconstruction. PMID- 4196466 TI - Complications of total hip replacement arthroplasty. PMID- 4196467 TI - The Amsel frustration effect: interpretations and research. PMID- 4196468 TI - [Blood rifampicin levels in cirrhotic tuberculous patients]. PMID- 4196469 TI - [Bacteriophage typing of Mycobacterium tuberculosis]. PMID- 4196470 TI - [Ossified bronchial carcinoid tumor]. PMID- 4196472 TI - Enhanced emigration of crevicular leukocytes mediated by factors in human dental plaque. PMID- 4196473 TI - Respiratory disease and ABO and rhesus blood groups. PMID- 4196471 TI - Observations on endopeptidases in human carious dentin. PMID- 4196474 TI - Long term maintenance of Theileria annulata strains by freezing at -70 degrees C. PMID- 4196475 TI - [The gas supply of hydrogen bacteria in submerged culture]. PMID- 4196476 TI - Hemophilia B in a phenotypically normal girl with XX (ring) XO mosaicism. PMID- 4196477 TI - Abnormal factor X(factor X Friuli) coagulation disorder. PMID- 4196478 TI - Hypofibrinogenemia after Echis colorata bite in man. PMID- 4196479 TI - Factors influencing the uptake of vitamin B 12 by normoblastic and vitamin B 12 deficient bone marrow cells. PMID- 4196480 TI - Heinz body susceptibility of red cells and exchange transfusion. PMID- 4196481 TI - The fibrinolytic enzyme system in malignant lymphomas. PMID- 4196482 TI - [The spontaneous standardized platelets adhesion and aggregation in the counting chamber. A simple way of determination of platelet function from small blood volumes]. PMID- 4196483 TI - Whole-body autoradiography of 1-tetrahydrocannabinol and 1(6) tetrahydrocannabinol in mouse. Pharmacokinetic aspects of 1 tetrahydrocannabinol and its metabolites. PMID- 4196484 TI - Factors influencing the secretion of human prolactin and growth hormone in menstrual and gestational women. PMID- 4196485 TI - Porcine coronaviruses: co-infection of cell cultures with transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus. PMID- 4196486 TI - [Statistics concerning 1000 cases of pharyngeal epithelioma treated by radiocobalt at the Curie Foundation. Particular study of results in relation to cervical adenopathies]. PMID- 4196487 TI - Heteroxanthin in Euglena gracilis. PMID- 4196488 TI - Action of lysozyme on Anabaena ambigua Rao. PMID- 4196489 TI - [Alcohol components of bacteriophyll a from Rhodospirillum rubrum]. PMID- 4196490 TI - Isolation of and production of antibody to cow chromaffin granule membrane. PMID- 4196491 TI - Membranes of Tetrahymena. 3. The effect of temperature on membrane core structures and fatty acid composition of Tetrahymena cells. PMID- 4196492 TI - An ultrastructural study of the red pulp of the spleen in malaria. PMID- 4196493 TI - Occlusion of the vortex veins. An experimental study. PMID- 4196494 TI - [Ionic force effect on form and dimensions of fibrinogen]. PMID- 4196495 TI - [Dielectric relaxation effects in mitochondrial suspensions in relation to their biological activity]. PMID- 4196496 TI - [Ultracentrifugation of 2 human bronchial mucins]. PMID- 4196497 TI - [Polyphosphates during multicellular development of Dictyostelium discoideum]. PMID- 4196498 TI - [Development of peroxidase activity and organification of iodide in the thyroid gland of Xenopus laevis (Daudin) during metamorphosis]. PMID- 4196499 TI - [Correlation between the expression of HL-A and P systems antigens in hybrid human x mouse cells and culture media (HATG, Standard, BUDR). Possible linkage of HL-A and P loci with the thymidine kinase locus]. PMID- 4196500 TI - [Yeasts and antitumoral vaccination, new data]. PMID- 4196501 TI - [Morphological study, using microcinematography and scanning electron microscopy, of the alveolar histiocyte after in vitro phagocytosis of plutonium oxide]. PMID- 4196502 TI - [Cortisol and corticosterone synthesis during the first week of life in the guinea pig]. PMID- 4196503 TI - [Amino acid composition of proteins from synaptic region membranes]. PMID- 4196504 TI - [Potentiality for organization and differentiation of non segmented somite mesoderm associated with axial tissue (notochord and neural tube) in the Anoures amphibians]. PMID- 4196505 TI - [Catecholamines distribution in caudate nucleus, putamen, pallidum and black substance of the rat brain]. PMID- 4196506 TI - [Haploidy in Theobroma cacao]. PMID- 4196507 TI - [Cytological study of lymphocytes from different lymphoid organs of normal mice]. PMID- 4196508 TI - [Demonstration of a zone adated to ionic transport in the intestine of the common carp (Cyprinus carpio L)]. PMID- 4196509 TI - [Effect of artificial atmospheric ionization on urinary sodium and potassium excretion]. PMID- 4196510 TI - [Coenzyme A of interscapular brown fat and liver during fasting in rats]. PMID- 4196511 TI - [Existence and thermostability of calcium binding proteins in intestinal and gill mucosas of different teleost fishes]. PMID- 4196512 TI - [Autoradiographic study of the effect of androgens on RNA synthesis in tissues of the male mouse genital tract]. PMID- 4196513 TI - [Neurosecretory cells and their localization during the vital cycle in the central nervous system of Crepidula fornicata (Phil.), hermaphrodite gastropod mollusca]. PMID- 4196514 TI - [Effect of previous experimental history on output and topography of responses in rats]. PMID- 4196515 TI - [Decrease in the longevity of Drosophila melanogaster caused by protection against natural ionizing radiations]. PMID- 4196516 TI - [Hydrostatic hyperpressures and survival of embryonal organs in chickens. Effect of compression speed]. PMID- 4196517 TI - [Experimental demonstration of germinal cells in the presumptive lateral mesoderm of the young gastrula of Pleurodeles waltii (urodele amphibian)]. PMID- 4196518 TI - [Structure of cerberiopsin II]. PMID- 4196519 TI - [Comparative study of the primary structure of human B and C and bovine C erythrocytic carbonic anhydrases]. PMID- 4196520 TI - [Demonstration of fixation of an enzyme on a superficial lipid layer]. PMID- 4196522 TI - [Distribution of C 14 -labeled erucic acid in normal or pregnant mice]. PMID- 4196521 TI - [Exogenous and endogenous insulin inhibit hyperlactacidemia induced in dogs by administration of phenformin]. PMID- 4196523 TI - [Effect of different nematodicides on Angiostrongylus cantonensis (Chen, 1935) at different periods of its development, in the rat]. PMID- 4196524 TI - [Relations between immunological events and the genetic control of enzymatic activity of macrophages and lymphocytes]. PMID- 4196525 TI - [Demonstration of a human splenothymic antigen and its presence in leukemias and the fetal thymus]. PMID- 4196526 TI - The Cancer Control Program of the National Cancer Institute. PMID- 4196527 TI - Unproven methods of cancer management. Krebiozen and carcalon. PMID- 4196528 TI - Cookbook cancer therapy. PMID- 4196529 TI - Vaccine trials for osteogenic sarcoma. A preliminary report. PMID- 4196530 TI - Rx of bladder cancer: complex and controversial. PMID- 4196531 TI - Colorectal polyps. PMID- 4196532 TI - William Stewart Halsted (1852-1922). PMID- 4196533 TI - The treatment of wounds with special reference to the value of the blood clot in the management of dead space. IV. Operations for carcinoma of the breast by William S. Halsted, M.D., reprinted from Johns Hopkins Hospital Reports, Vol. II, No. 5, 277-280, 1891. PMID- 4196534 TI - An approach to the control of carcinoma of the endometrium. PMID- 4196535 TI - A comparison of different compounds for TBG-blocking used in radioimmunoassay for tri-iodothyronine. PMID- 4196536 TI - [Studies on metabolic chemical balance using new test amino acid solutions for parenteral feeding]. PMID- 4196537 TI - A new extrapigmentary effect of alpha-MSH. Promotion of sodium uptake in the heart of toads and rats. PMID- 4196538 TI - A study of immunoglobulins in protein calorie malnutrition. PMID- 4196539 TI - Immunoglobulins and C 3 levels in normal Indians: details of methodology, standardization, variation and statistical methods. PMID- 4196540 TI - A new simplified sugar medium for fermentation test with plague, pseudotuberculosis and diphtheria organisms. PMID- 4196541 TI - Viability of N. gonorrhoeae in transport media. PMID- 4196542 TI - [Action of Ercevit P on resorption of retinal hemorrhages]. PMID- 4196543 TI - Peripheral ossifying fibroma: report of case. PMID- 4196544 TI - Preservation and biodegradation of the morphogenetic property of bone matrix. PMID- 4196545 TI - [Identification of Pseudomonas and related organisms]. PMID- 4196546 TI - [Progress in the virological diagnostic procedures in cold syndromes]. PMID- 4196547 TI - "Rynacrom" (sodium cromoglycate). PMID- 4196548 TI - [Treatment of functional intestinal disturbances]. PMID- 4196549 TI - [Systemic dysplasia of the connective tissue. Discussion of 2 cases with uncertain classification]. PMID- 4196550 TI - [Possibilities and limitations of radioiodine therapy in thyroid neoplasms]. PMID- 4196551 TI - Inpatient surgery on an ambulatory basis. PMID- 4196552 TI - [Alpha 1 antitrypsin deficiency during chronic bronchopneumopathies]. PMID- 4196553 TI - Protein calorie malnutrition and infection with hepatitis-associated antigen. PMID- 4196554 TI - Serum concentrations of ampicillin in newborn infants after oral administration. PMID- 4196555 TI - Hyperammonemia: another hazard in parenteral alimentation. PMID- 4196556 TI - Nasogastric tube feedings. Practical considerations in prescription and evaluation. PMID- 4196557 TI - Nutritional care after head and neck surgery. PMID- 4196558 TI - Changing concepts in prenatal care. PMID- 4196559 TI - Virus-like particles in natural scrapie of the sheep. PMID- 4196560 TI - The use of fluorescent antibody technqiues to detect Theileria parva in the salivary glands of the tick Rhipicephalus appendicalatus. PMID- 4196561 TI - Observations on the haematology of experimentally induced Babesia argentina and B. bigemina infections in splenectomised calves. PMID- 4196562 TI - Haemoglobin reactive protein in cattle: partial characterisation. PMID- 4196563 TI - Chemical and microbial degradation of ten selected pesticides in aquatic systems. PMID- 4196565 TI - [10,000 days until the year 2000]. PMID- 4196564 TI - [Fibrous dysplasia and soft tissue myxomas]. PMID- 4196566 TI - [Physiology of nitrate reduction in Pseudomonas aeruginosa]. PMID- 4196567 TI - Laboratory experiments with uropathogenic bacteria and chlorhexidine. PMID- 4196568 TI - Metabolism of radioactive-labeled fat emulsions in the postoperative and posttraumatic period. PMID- 4196569 TI - Vitamin B 12 absorption in protein-calorie malnourished children and during recovery: influence of protein depletion and of diarrhea. PMID- 4196570 TI - Malnutrition studies in Macaca mulatta. II. The effect on organ size and skeletal growth. PMID- 4196571 TI - Value of immunodiffusion tests in the diagnosis of systemic mycotic diseases. PMID- 4196572 TI - Communication among primates. PMID- 4196573 TI - Heart: excitation-contraction coupling. PMID- 4196575 TI - Lymphocyte heterogeneity and function. PMID- 4196574 TI - Normal tissue tolerance to particle and heavy ion radiation. PMID- 4196576 TI - [Pharmacology and toxicology of the anticonvulsant agent clonazepam]. PMID- 4196577 TI - [Trimethoprim levels in the serum, cerebrospinal fluid, and tissues of the guinea pig]. PMID- 4196578 TI - The DNA of Tetrahymena pyriformis GL strain. A mild method for preparation and its characterization. PMID- 4196579 TI - Immunologic studies on intracellular isoenzymes; the mitochondrial and cytoplasmic leucyl-tRNA synthetases. PMID- 4196580 TI - The specific immunoprecipitation of polyribosomes synthesizing an immunoglobulin light chain. PMID- 4196581 TI - A comparison of effective thyroxine ratio and free thyroxine in serum. PMID- 4196582 TI - [Two cases of von Recklinghausen's disease with juxta-basal telangiactasia]. PMID- 4196583 TI - The mechanism of the antihypertensive action of -methyldopa in hypertensive rats. PMID- 4196584 TI - Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin. PMID- 4196585 TI - Diphtheria toxin and related proteins. II. Kinetic studies on intoxication of HeLa cells by diphtheria toxin and related proteins. PMID- 4196586 TI - Diphtheria toxin and related proteins. 3. Reconstitution of hybrid "diphtheria toxin" from nontoxic mutant proteins. PMID- 4196587 TI - Magnetic circular dichroism of cobalt-copper and zinc-copper bovine superoxide dismutase. PMID- 4196588 TI - Transport of vitamin B 12 in Escherichia coli. Location and properties of the initial B 12 -binding site. PMID- 4196589 TI - Oxidation of catechol in plants. IV. Purification and properties of the 3,4,3',4' tetrahydroxydiphenyl-forming enzyme system from Tecoma leaves. PMID- 4196590 TI - Combination of specific antibodies with the human vitamin A-transporting protein complex. PMID- 4196591 TI - Aspergillus fumigatus in samples of moldy silage. PMID- 4196592 TI - Basal body addition in ciliary rows of Tetrahymena pyriformis. PMID- 4196593 TI - [High risk pregnancies. Prognostic value and plasma levels of human chorionic somatomammotropin]. PMID- 4196594 TI - Tyrosine and catecholamine metabolism in wild-type Drosophila melanogaster and a mutant, ebony. PMID- 4196595 TI - Radiologic seminar CXXVII: jejunal diverticulosis. PMID- 4196596 TI - Planning for dialysis and transplantation facilities. PMID- 4196597 TI - Megavoltage port radiography for therapy evaluation. PMID- 4196598 TI - [Acoustic neurilemmoma of prolonged development during an atypical diffused fibromatosis]. PMID- 4196599 TI - Lithium fluoride: an inexpensive calibration check for the general hospital. PMID- 4196600 TI - The value of lumbar spinal tap in the diagnosis of closed head injury. PMID- 4196601 TI - [Purification and modification of the catalytic properties of amine oxidases]. PMID- 4196602 TI - [The biological and therapeutic value of 4-aminopteroylaminoadipic acid]. PMID- 4196603 TI - WHO Expert Committee on Rabies: sixth report. PMID- 4196604 TI - Pharmacogenetics. Report of a WHO scientific group. PMID- 4196605 TI - Reye syndrome. 3. The hypoglycemia. PMID- 4196606 TI - Infantile cirrhosis with hereditary alpha 1 -antitrypsin deficiency. Clinical improvement in two siblings. PMID- 4196607 TI - Tuberculosis of the skin. PMID- 4196608 TI - [Useful data in genetic counseling]. PMID- 4196609 TI - [A case of cyclopia with 13-15 trisomy]. PMID- 4196610 TI - [Complications of juvenile diabetes after 15 years' evolution]. PMID- 4196611 TI - [Headaches in patients with vascular deficiency and their treatment with a raubasine-dihydroergocristine association]. PMID- 4196612 TI - [Chetotaxy of the rhodometopic cercaria: Cercaria doricha pigmentata Wright 1956. Hypothesis on its systematic position]. PMID- 4196613 TI - [Experimental data on the contamination of Anguilla anguilla (L.) by chromium 51 and its excretion]. PMID- 4196614 TI - [Preliminary study of the precocity of satellite chromosomes during meiosis in male Asellus aquaticus Linne (isopod Crustaceae)]. PMID- 4196615 TI - [Postnatal synthesis of hemoglobin F in chickens]. PMID- 4196616 TI - [Comparative study of the biological metabolism of californium and other transuranic elements]. PMID- 4196617 TI - [Effect of DDT on the urogenital tract of chick and quail embryos]. PMID- 4196618 TI - [Demonstration of histidine fluorescence]. PMID- 4196619 TI - [Effect of low temperatures on bacterial luminescence and mechanism of emission]. PMID- 4196620 TI - [Peroxidase activity of certain hemoglobin derivatives and of their complexes with haptoglobin]. PMID- 4196621 TI - [Effect of concanavalin A on the transplantability of transformed cells]. PMID- 4196622 TI - [Evolution of the average age of members of the Academy of Sciences since the foundation of the Academy]. PMID- 4196623 TI - [Evolution of the average age of authors, since 1850, at the time of their publications in chemical sciences]. PMID- 4196624 TI - [Therapy of pyelonephritis]. PMID- 4196625 TI - [Behavior of carbohydrate metabolism in parenteral feeding]. PMID- 4196626 TI - [Determination of the extracellular space with Cr 51 -EDTA in the auricular musculature of guinea pigs]. PMID- 4196627 TI - Disappearance of radioactivity from plasma following intravenous administration of tritiated thyrotrophin-releasing hormone (Ro 8-6270) to man. PMID- 4196628 TI - The visual component in the courtship of Drosophila melanogaster. PMID- 4196629 TI - The lipolytic activity of Micrococcaceae from human and animal sources. PMID- 4196630 TI - The ingestion of gonococci by epithelial cells. PMID- 4196631 TI - Attachment of gonococci to the urethral mucosal cells of patients with gonorrhoea -a critical early stage in the pathogenesis of the infection? PMID- 4196632 TI - Raised intracranial pressure and cerebral blood flow. 2. Supratentorial and infratentorial mass lesions in primates. AB - Changes in cerebral blood flow with increasing intracranial pressure were studied in anaesthetized baboons during expansion of a subdural balloon in one of two different sites. With an infratentorial balloon, cerebral blood flow bore no clear relation to intracranial pressure, but was linearly related to cerebral perfusion pressure. Apart from an initial change in some animals, cerebrovascular resistance remained constant with increasing intracranial pressure, and autoregulation appeared to be lost from the outset. With a supratentorial balloon, cerebral blood flow remained constant as intracranial pressure was increased to levels around 60 mm Hg, corresponding to a cerebral perfusion pressure range of approximately 100 to 40 mmHg. Cerebrovascular resistance fell progressively, and autoregulation appeared to be effective during this phase. At higher intracranial pressure levels (lower cerebral perfusion pressure levels), autoregulation was lost and cerebral blood flow became directly dependent on cerebral perfusion pressure. The importance of the cause of the increase in intracranial pressure on the response of the cerebral circulation and the relevance of these findings to the clinical situation are discussed. PMID- 4196633 TI - Outgrowth of Bacillus cereus spores harboring bacteriophage CP-51 DNA. I. Initiation of bacteriophage development. AB - Time of initiation of bacteriophage CP-51 RNA synthesis, inhibition of host DNA synthesis, initiation of CP-51 DNA synthesis, and release of phage was determined in infected Bacillus cereus cells and outgrowing spores harboring phage DNA. The development of phage in outgrowing spores is initiated 45 min after induction of spore germination and then proceeds at a rate similar to that observed in infected cells. Although spore RNA synthesis is inhibited by the presence of chloramphenicol or puromycin during germination, these antibiotics do not inhibit initiation of phage DNA transcription in outgrowing spores. PMID- 4196634 TI - Rabies group-specific ribonucleoprotein antigen and a test system for grouping and typing of rhabdoviruses. AB - Cell-associated ribonucleoprotein (RNP) was isolated from BHK-21 cells infected with several strains of rabies and rabies-related viruses. The RNP-antigen from rabies and related viruses induced the formation of complement-fixing, precipitating, and immunofluorescent antibodies, and proved to be the group specific antigen common to all rabies viruses. Antigens of the envelope which induce virus-neutralizing antibodies are apparently determinative for the serotype of a virus as evidenced by two-way neutralization tests. A combination of these methods seems to be a useful approach to the serological grouping and typing of rhabdoviruses. PMID- 4196635 TI - Genetic study of suppressor-sensitive mutants of the Bacillus subtilis bacteriophage phi 29. AB - With bacteriophage phi29 of Bacillus subtilis 133, suppressor-sensitive (sus) hydroxylamine mutants have been isolated. Intracistronic and intercistronic quantitative complementation placed the mutants in 13 cistrons, and three-factor crosses have been used to assign an unambiguous order for 10 cistrons. Recombination frequencies have been presented for several regions of the genome to facilitate comparison of the sus system with the previously published temperature-sensitive mapping systems. PMID- 4196636 TI - [Infections during the treatment of leukemia or malignant lymphoma]. PMID- 4196637 TI - [Dosed physical loading as a method of evaluating the results of treating ischemic heart disease]. PMID- 4196638 TI - [Ultrastructure of Streptomyces during the biosynthesis of secondary metabolites. IV. Transport of tetraene antibiotic from the cell into the medium]. PMID- 4196639 TI - [Effect of group B vitamins on the multiplication rate of Salmonella and Brucella]. PMID- 4196640 TI - Protein differences associated with a phototransduction mutant of Drosophila. PMID- 4196641 TI - Phencyclidine action on neural mechanisms of somesthesis. PMID- 4196642 TI - Lecithin-sphingomyelin ratio and a rapid test for surfactant in amniotic fluid. A comparison. PMID- 4196643 TI - Daily fetal movement recording and fetal prognosis. PMID- 4196644 TI - Interocular transfer of reversed and nonreversed discrimination via the anterior commissure in monkeys. PMID- 4196645 TI - Sexual behaviour of White Leghorn cocks bearing basal hypothalamic lesions in various locations. PMID- 4196646 TI - Peripheral and central stimulus detection in auditory pathways of monkeys. PMID- 4196647 TI - A method for the construction and use of contact occluders for small animals. PMID- 4196648 TI - [Determination of alpha-1-antitrypsin and immunoglobulin A in bronchial and pulmonary diseases (151 cases)]. PMID- 4196649 TI - Diabetic keto-acidosis complicated by disseminated intravascular coagulation. PMID- 4196650 TI - Gonococcal arthritis in pregnancy. PMID- 4196651 TI - Anorectal gonorrhea presenting as ulcerative proctitis. PMID- 4196652 TI - Colonization of burns by Streptococcus faecalis related to contaminated porcine xenografts. PMID- 4196653 TI - [Result of perennial administration of depot nitroglycerine in ambulatory angina pectoris]. PMID- 4196654 TI - [On a case of leiomyosarcoma of the kidney]. PMID- 4196655 TI - Massive extracranial hematomas in two squirrel monkeys. PMID- 4196656 TI - [Therapeutic possibilities in multiple epitheliomas of the trunk skin]. PMID- 4196657 TI - Canine alimentary neoplasia. PMID- 4196658 TI - [Morphology of the postembryonal bursa of Fabricius following hormonal bursectomy]. PMID- 4196660 TI - [The fine structure of eosinophilic granulocytes of the domestic duck (Anas platyrhynchos dom.)]. PMID- 4196659 TI - [Structure of brain gangliosides and of neuraminic-acid-containing oligosaccharides in milk]. PMID- 4196661 TI - [Fetal development of the NMRI mouse]. PMID- 4196662 TI - [In-vitro studies on the amino acid secretion in the rumen]. PMID- 4196663 TI - [Urinary estrogen determination in the dog during estrus and pregnancy]. PMID- 4196664 TI - On the pharmacodynamics of Benzatcin. PMID- 4196665 TI - Tremor in diving. PMID- 4196666 TI - Effect of various microorganisms found in cosmetics on the normal and injured eye of the rabbit. PMID- 4196667 TI - Ocular and central nervous system findings in tetraploid-diploid mosaicism. PMID- 4196668 TI - Conjunctivitis associated with Coxsackie B-1 virus in a laboratory worker. PMID- 4196669 TI - Repair after xenon arc photocoagulation. 3. An electron microscopic study of the evolution of retinal lesions in rhesus monkeys. PMID- 4196670 TI - Severe problems with gastric emptying after gastric surgery. PMID- 4196671 TI - [Physiology and pharmacology of sodium, potassium, and calcium movements across the membrane]. PMID- 4196672 TI - The phenogenetics of a super-suppressor in Drosophila melanogaster. II. Suppression and back-mutation. PMID- 4196673 TI - Deep freezing of boar semen. I. Effects of diluent composition, protective agents, and method of thawing on survival of spermatozoa. PMID- 4196674 TI - Radioisotope-survey of metastases of breast carcinoma to bone using Sr-87m and whole body scanner. PMID- 4196675 TI - An exo- -N-acetylglucosaminidase from Bacillus subtilis B; characterization. PMID- 4196676 TI - Kinetic properties of microsomal UDP-glucuronyltransferase. Evidence for cooperative kinetics and activation by UDP-N-acetylglucosamine. PMID- 4196677 TI - Differentiation of homologous forms of hepatic microsomal UDP glucuronyltransferase. I. Evidence for the glucuronidation of o-aminophenol and p nitrophenol by separate enzymes. PMID- 4196678 TI - Differentiation of homologous forms of hepatic microsomal UDP glucuronyltransferase. II. Characterization of the bilirubin conjugating form. PMID- 4196679 TI - [Physico-chemical and biological characteristics of ascitic fluid induced in mice by Freund's adjuvant]. PMID- 4196680 TI - Adrenergic mechanism in Tetrahymena. I. Changes in monoamine oxidase activity during growth. PMID- 4196681 TI - Storage of insecticides in the fat body of Spodoptera littoralis (Boisd.) as a possible mechanism of resistance. PMID- 4196682 TI - Intracellular response by Tetrahymena pyriformis to fluids from unimmunized animals. PMID- 4196683 TI - Resistance to carbon dioxide, an anoxic stress in Drosophila melanogaster. PMID- 4196684 TI - A study of the differentiation of bracts in Drosophila melanogaster using two mutations, H 2 and sv de . PMID- 4196686 TI - [Thyrotropin releasing hormone (TRH)]. PMID- 4196685 TI - [Hypertension caused by vascular lesions in neurofibromatosis]. PMID- 4196687 TI - Mechanical factors in the design of chronic recording intracortical microelectrodes. PMID- 4196688 TI - Immunochemical studies of two human liver carboxyl esterases. PMID- 4196689 TI - The filtration coefficient of the intraocular vasculature as measured by low pressure perfusion in a primate eye. PMID- 4196690 TI - The effect of arterial PCO 2 on relative retinal blood flow in monkeys. PMID- 4196691 TI - The intercellular junctional complexes of retinal pigment epithelia. PMID- 4196692 TI - Effect of exogenous interferon on herpetic keratitis in rabbits and monkeys. PMID- 4196693 TI - Lactase and other enzymes bound to a phenol-formaldehyde resin with glutaraldehyde. PMID- 4196694 TI - Gel filtration of thyroxine-binding proteins. Identification of rat plasma protein fractions separated on sephadex G-200. PMID- 4196695 TI - Separation of NTA and EDTA chelates by thin-layer chromatography. PMID- 4196696 TI - Disodium cromoglycate. PMID- 4196697 TI - High voltage electron microscopy of the central nervous system in Golgi preparations. PMID- 4196699 TI - The hypothermic effect of tetrodotoxin in the unanaesthetized cat. AB - 1. The hypothermic effect on unanaesthetized cats of tetrodotoxin injected I.V. or into the lateral cerebral ventricle was examined.2. At an ambient temperature (T(a)) of 22 degrees C, tetrodotoxin given intraventricularly was over 400 times more potent in lowering body temperature (T(b)) than when given I.V. The magnitude of the hypothermia was dose-dependent for both routes. Decreases in T(b) as great as 6.8 degrees C were induced by infusions or multiple injections of tetrodotoxin into the ventricle.3. Tetrodotoxin also lowered T(b) at T(a) = 13, 30 or 35 degrees C. Tachypnoea, which lasted for longer durations and which became more intense the higher the T(a), accompanied development of hypothermia. Shivering was observed only during recovery from hypothermia at 13 degrees C.4. During the tetrodotoxin-induced hypothermia, animals were still able to regulate against environmental thermal stresses.5. EDTA disodium salt, leucocytic pyrogen and prostaglandin E(1) antagonized the hypothermic effect of tetrodotoxin when they were administered during recovery from tetrodotoxin.6. Activation of heat loss mechanisms, and the absence of compensatory shivering during development of hypothermia after tetrodotoxin administration, plus lowering of T(b) by tetrodotoxin at T(a) above as well as below the thermoneutral temperature, indicate that lowering of the thermoregulatory set-point is the mechanism by which centrally or peripherally administered tetrodotoxin lowers T(b). Further evidence for set-point lowering after intraventricular administration of tetrodotoxin is provided by persistence of the ability to regulate against both heat and cold stresses during hypothermia. The possibility that the decrease in set-point could be due to the well known action of tetrodotoxin to block transient increases in membrane sodium ion conductance is discussed in terms of a recent hypothesis regarding ionic control of the thermoregulatory set-point. PMID- 4196698 TI - Differential release of acetylcholine from the hypothalamus and mesencephalon of the monkey during regulation. AB - 1. In unanaesthetized monkeys acclimated to primate chairs, 101 isolated sites in the hypothalamus and mesencephalon were perfused at a rate of 30-50 mul./min by means of push-pull cannulae. The perfusate, which contained an anticholinesterase, was assayed for acetylcholine (ACh) activity on the guinea pig ileum in the presence of neostigmine.2. The body temperature of each animal was monitored continuously during an experiment by colonic and brain thermistors. To alter the ambient temperature by 15-20 degrees C, either a stream of warm air was passed over the monkey's trunk or containers of ice were placed in its chair chamber to cool the same region.3. Assays of the effluent revealed that the release of ACh varied according to the ambient temperature as follows: elevated only during cooling; elevated only during warming; elevated by both thermal stimuli; suppressed only by cooling; suppressed only by warming; suppressed by both thermal stimuli; elevated during cooling but suppressed by warming; and elevated by warming and suppressed by cooling.4. A composite anatomical ;mapping' of all perfusion sites revealed that in response to either peripheral cooling or warming, the output of ACh varied at only 36% of all sites anterior to the mid hypothalamic plane, but at 65% of those loci caudal to this coronal plane.5. In the anterior, preoptic area, cooling enhanced the output of ACh at 88% of the active releasing sites, whereas warming reduced the release of ACh at 80% of these perfusion loci. Posterior to this region, ACh release was elevated by cooling at about half of the active releasing sites, but lowered by warming at nearly every active perfusion locus. Within the mesencephalon, the ratio of the temperature-induced change in ACh release was similar but in an opposite direction, since the level of ACh in the effluent collected from two out of three sites was augmented by cooling, but diminished by warming.6. These results provide additional evidence for the neurochemical model of Myers & Yaksh (1969), which suggests that a cholinergic pathway originating in the anterior, preoptic region transmits efferent signals for heat production. Further, within the posterior hypothalamic area as well as in the mesencephalon of the monkey, the characteristics of the ACh releasing sites reflect a function delegated primarily to heat gain, although evidence of a cholinergic pathway for the heat loss system is also presented. PMID- 4196700 TI - Scanning electron microscopy of the normal and BCG-stimulated primate respiratory tract. PMID- 4196701 TI - Immunoglobulins as aspecific opsonins. 3. The opsonizing power of fragments of polyclonal and monoclonal immunoglobulin G. PMID- 4196702 TI - The effect of lymphocyte supernatant fluids on the intracellular growth of virulent tubercle bacilli. PMID- 4196703 TI - The induction by Listeria monocytogenes and plant mitogens of lymphocyte supernatant fluids which inhibit the growth of Mycobacterium tuberculosis within macrophages in vitro. PMID- 4196704 TI - An intravenous fat emulsion as a nitrogen sparer: comparison with lucose. PMID- 4196705 TI - Technique of injection into the spinal cord of monkeys. PMID- 4196706 TI - The pathophysiology of irreversible hemorrhagic shock in monkeys. PMID- 4196707 TI - Inhibition of collagen synthesis by the proline analogue cis-4-hydroxyproline. PMID- 4196708 TI - [ETR-test during pregnancy]. PMID- 4196709 TI - [Radioimmunoassay of IgE using Sephadex-bound antibodies]. PMID- 4196710 TI - The use of 7-chlorolincomycin in the treatment of childhood respiratory disease. PMID- 4196711 TI - Aflatoxin B 1 producing potential of isolates of Aspergillus flavus Link ex Fries from cotton, maize and wheat. PMID- 4196712 TI - Clinical and manometric effects of nitroglycerin in diffuse esophageal spasm. PMID- 4196713 TI - Replacement therapy for inherited enzyme deficiency. Use of purified ceramidetrihexosidase in Fabry's disease. PMID- 4196714 TI - The environmental causes of aggression. PMID- 4196715 TI - [Measurement and analysis of long-term 22 Na retention using a whole-body counter]. PMID- 4196716 TI - [Energy calibration for electrons from A 35MeV linear accelerator by thresholds for nuclear reactions]. PMID- 4196717 TI - Tuberculosis drug therapy. A review. PMID- 4196718 TI - The time course of preparatory processes in split-brain monkeys performing a variable foreperiod reaction time task. PMID- 4196719 TI - Modifications in cortically-induced peripheral motor nerve activity induced by the center median in the cat and the squirrel monkey. PMID- 4196720 TI - Urinary epinephrine and norepinephrine responses to chair restraint in the monkey. PMID- 4196721 TI - The enhanced efficacy of disodium cromoglycate (DSCG) in DSCG predosed rats. PMID- 4196722 TI - Serological responses of patas monkeys (Erythrocebus patas) to vaccination against cholera and yellow fever. PMID- 4196723 TI - Vacuole formation in human erythrocyte ghosts. PMID- 4196724 TI - The role of renal arteriography in pediatric hypertension. PMID- 4196725 TI - Symposium on the role of heavy particle radiation in the treatment of cancer. Introduction. PMID- 4196726 TI - Radiobiology of heavy particle radiation therapy: cellular studies. PMID- 4196727 TI - High-LET radiation: clinical facilities available with neutron beams. PMID- 4196728 TI - Pretherapeutic investigations with accelerated heavy ions. PMID- 4196729 TI - A hospital-based superconducting accelerator facility for negative pi-meson beam radiotherapy. PMID- 4196730 TI - Clinical dosimetry for negative pi mesons. PMID- 4196731 TI - Preparation, physiology, and dosimetry of 111 In-labeled radiopharmaceuticals for cisternography. PMID- 4196732 TI - [Bacterial resistance to some cationic surface-active agents]. PMID- 4196733 TI - [Problems of antibiotic and antibacterial long-term therapy in internal medicine]. PMID- 4196734 TI - [Conservative long-term therapy of chronic kidney diseases]. PMID- 4196735 TI - [Therapy of chronic glomerulonephritis using indomethacin]. PMID- 4196736 TI - [Study of some clinical and immunological indices in antibiotic and serum therapy of experimental paratyphoid]. PMID- 4196737 TI - Salivary IgA in periodontal disease. PMID- 4196738 TI - A rapid mycobacterial drug susceptibility test. PMID- 4196739 TI - Laboratory suggestions: a method for teaching the technic of electroimmunodiffusion for detection of the australia antigen and other proteins. PMID- 4196740 TI - Letters to the editor: quantitation of cerebrospinal fluid proteins. PMID- 4196741 TI - Tobramycin: bacteriological evaluation. PMID- 4196742 TI - The effect of Pa CO2 on the metabolism of ischemic brain in squirrel monkeys. PMID- 4196743 TI - Fat metabolism in higher plants. LV. Acetate uptake and accumulation by class I and II chloroplasts from Spinacia oleracea. PMID- 4196744 TI - Choline sulfatase of Pseudomonas aeruginosa. PMID- 4196745 TI - Long-term continuous exposure to sulfuric acid mist in cynomolgus monkeys and guinea pigs. PMID- 4196746 TI - The in vitro incorporation of ( 3 H)thymidine into DNA and of 32 P into phospholipids and RNA in the aorta of Rhesus monkeys during early atherogenesis. PMID- 4196747 TI - Fastigial nucleus connections to the septal region in monkey and cat: a demonstration with evoked potentials of a bilateral pathway. PMID- 4196749 TI - Age effects of social behavior deficits following prefrontal lesions in monkeys. PMID- 4196748 TI - [Prevention of morbus haemolyticus neonatorum and of transitory hyperbilirubinemias of newborn infants through an enzyme inductor combination]. PMID- 4196750 TI - Multiple coding of species-specific vocalizations in the auditory cortex of squirrel monkeys. PMID- 4196751 TI - An ultrastructural study of the centre median and ventrolateral thalamic nuclei of the monkey. PMID- 4196752 TI - An ultrastructural study of the termination of afferent fibres within the ventrolateral and centre median nuclei of the monkey thalamus. PMID- 4196753 TI - The effect of prenatal malnutrition on dimensions of cerebral cortex. PMID- 4196754 TI - [A fertile trisomic male of urodele amphibian Pleurodeles waltlii Michah. Study of its descendants]. PMID- 4196755 TI - [Comparison of lipid metabolism in the hepatopancreas of Pachygrapsus marmoratus Fabricius (brachyourous decapod) in control animals and those with operated ocular pedunculus in relation to the molting cycle]. PMID- 4196756 TI - [Paroxysmal depolarisation of the soma and axonic discharge of the same neuron treated with metrazol (autoactive neurons in Helix)]. PMID- 4196757 TI - [Electron microscope study of early cellular degeneration in articular mesenchyma of the chick embryo]. PMID- 4196758 TI - [Conditioning and extinction with the automated pole climbing technic]. PMID- 4196759 TI - [Radioprotective effect of C 511 injected in mice 24 hours before lethal-dose irradiation]. PMID- 4196760 TI - [Tolerance to delta 9-tetrahydrocannabinol in the hypertensive rat]. PMID- 4196761 TI - [First demonstration of morphological differences in lymphocytes belonging to thymo-dependent and thymo-independent cell populations]. PMID- 4196762 TI - [Influence of histones on phagocytosis of homologous and heterologous erythrocytes by macrophages]. PMID- 4196763 TI - [Functional aspects of thyroid cells studied by means of scanning electron microscopy: intracellular detection of iodine by simultaneous X-ray microdiffraction]. PMID- 4196764 TI - [Relationship between contraction and membrane currents of the smooth muscle fascia of the uterus]. PMID- 4196765 TI - [Circadian rhythm of the effect of carbon monoxide on the emission of carbonic gas by rats in a group]. PMID- 4196766 TI - [New radioisotopic assay of 17 alpha steroid hydroxylase]. PMID- 4196768 TI - [Effect of radioprotection at different periods on the longevity of Drosophila melanogaster]. PMID- 4196767 TI - [Bioelectric reactions of a giant secretory neuron (Aplysia depilans)]. PMID- 4196769 TI - [Theoretical study of the vicinal coupling between NH and NCH 3 protons in N methylacetamide: model of the NC binding of peptide residues]. PMID- 4196770 TI - [Qualitative analysis of wine peptides by means of ion exchange chromatography]. PMID- 4196771 TI - [Genetic independence of 2 molecular forms of bovine erythrocytic carbonic anhydrase]. PMID- 4196772 TI - [Partial purification and study of different properties of 5-hydroxy-tryptophan decarboxylase from rat brain]. PMID- 4196773 TI - [Purification and enzymatic properties of galactosidase from fenugrec germinated seeds]. PMID- 4196774 TI - [2,3-Diphosphoglycerate variation in human erythrocytes in relation to hematocrit]. PMID- 4196775 TI - [Multiplication of the bacteriolytic agent Bdellovibrio bacteriovorus and intensity of bacteriolysis according to the initial density in host bacteria]. PMID- 4196776 TI - [In vitro study of contagious sheep ecthyma virus]. PMID- 4196777 TI - [Immunosuppression and role of interferon in hamsters infected with rabies virus]. PMID- 4196778 TI - [Induction of lymphoblastic transformation with delta-9-tetrahydrocannabinol in mice]. PMID- 4196779 TI - [Monofactorial heredity of autogenesis in Aedes (Ochlerotatus) detritus (Haliday, 1833) (Diptera Culicidae)]. PMID- 4196780 TI - [Cytologic study of the postnatal differentiation of interstitial testis cells of the Japanese quail]. PMID- 4196781 TI - Experimental immunization with attenuated mutants of Pseudomonas aeruginosa. PMID- 4196782 TI - Autodegradation of RNA of bacterial ribosomes. PMID- 4196783 TI - Corticosteroid ointments: comparison by two human bioassays. PMID- 4196784 TI - Value of an acetaminophen-chlorzoxazone combination (parafon forte) in the treatment of acute musculoskeletal disorders. PMID- 4196785 TI - Evaluation of a bacteriostatic soap, P-300, on skin flora of patients in protected environments. PMID- 4196786 TI - A double-blind comparison of thioridazine (Mellaril) versus diazepam (valium) in patients with chronic mixed anxiety and depressive symptoms. PMID- 4196787 TI - On the anti-anxiety properties of a new benzodiazepine, ORF 8063. PMID- 4196788 TI - When to use cytotoxic drugs in rheumatoid arthritis. PMID- 4196789 TI - Planning a treatment program for rheumatoid arthritis. PMID- 4196790 TI - A contribution to the microbiology of urethritis. PMID- 4196791 TI - A comparison between the clearances of inulin, endogenous creatinine and 51 Cr EDTA. PMID- 4196792 TI - Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). I. The locus caeruleus. PMID- 4196794 TI - Increased virulence of the E vaccine strain of Rickettsia prowazeki passaged in the lungs of white mice and guinea pigs. PMID- 4196793 TI - Mechanisms in the suppression of delayed hypersensitivity in the guinea pig by 6 mercaptopurine. AB - The mechanism of suppression, of delayed hypersensitivity to tuberculoprotein by 6-mercaptopurine (6-MP) was studied in guinea pigs. Under the conditions of the protocol, suppression of tuberculin delayed skin test reactivity was not associated with a significantly altered end-organ response to mediators of permeability. No significant alteration of in vivo lymphoid activity, as measured by reconstitution studies, was found. In addition, lymphoid cells from 6-MP treated animals reacted in a fashion similar to those of placebo-treated animals with respect to (a) antigen-induced lymphocyte proliferation, (b) antigen-induced liberation of macrophage inhibitory factor activity, (c) direct inhibition by antigen of peritoneal exudate cell migration. Conversely, suppression was seen in levels of blood monocytes and in vitro function of macrophages from 6-MP-treated animals in several respects: (a) adherence to glass, (b) migratory rate, (c) phagocytic capacity. Therefore, it would appear that a ma]or mechanism of 6-MP induced suppression of delayed hypersensitivity is through its action on effector cells. PMID- 4196795 TI - Use of the microprecipitation method in agar gel (MPA) in the diagnostics of toxoplasmosis. 3. Correlation of MPA, complement-fixation reaction (CFT) and Sabin-Feldman's dye test (SFT) in serodiagnosis of human toxoplasmosis. PMID- 4196796 TI - Prevention of development of carriers in typhoid and paratyphoid fever. PMID- 4196797 TI - Hyaluronidase applied to the gingiva of rhesus monkeys. PMID- 4196798 TI - International trends toward humanization of health services. PMID- 4196800 TI - [Retinopathy in the course of Waldenstrom's macroglobulinemia]. PMID- 4196799 TI - [Distinct rickets during anticonvulsant long-term therapy]. PMID- 4196802 TI - All volunteer: military medicine tomorrow. PMID- 4196803 TI - Case for diagnosis. PMID- 4196801 TI - Contraceptive steroids: modifications of carbohydrate and lipid metabolism. PMID- 4196804 TI - PABA. A more effective sunscreen. PMID- 4196805 TI - A survey to assess potential human disease hazards along proposed sea level canal routes in Panama and Colombia. 3. Survey methods. PMID- 4196806 TI - Patterns of illicit drug use in viral hepatitis patients. PMID- 4196807 TI - Prognostic scales for personality disorders in the Naval Service. PMID- 4196809 TI - The evolution of the support of medical research in the Veterans Administration. PMID- 4196808 TI - Characteristics of naval recruits with histories of drug abuse. PMID- 4196810 TI - [Meningococcal infection in children]. PMID- 4196811 TI - [Disodium cromoglycate in the treatment of grass-pollen asthma]. PMID- 4196812 TI - Aflatoxicosis in the laying Japanese quail (Coturnix coturnix japonica). PMID- 4196813 TI - Nonsusceptibility of some avian species to turkey leucocytozoon infection. PMID- 4196814 TI - Avian riboflavinuria. 8. The fate of the riboflavin-binding protein-riboflavin complex during incubation of hen's eggs. PMID- 4196815 TI - Extraction of calcium from blood fibrin with a solution of tetrasodium ethylenediaminetetraacetate (Na4EDTA). PMID- 4196816 TI - Thyroid metabolism of chickens. 1. Estimation of hormone concentration by the thyroxine binding globulin technique. PMID- 4196817 TI - [Role of the hypothalamo-hypophyseal system in the regulation of the transcortin level in rat plasma]. PMID- 4196819 TI - The nurse's role in parenteral hyperalimentation. PMID- 4196820 TI - 104 days with Rodney K. PMID- 4196821 TI - Dodecyldiaminoethyl glycine as an inhibitor of bacteria, fungi and dental plauqes. PMID- 4196818 TI - [Effect of innervative disorders and the administration of autonomotropic substances on kidney sensitivity to desoxycorticosterone]. PMID- 4196822 TI - [Value of the use of a combination of photons and electrons in radiotherapy]. PMID- 4196823 TI - [A cellular schwannoma within the framework of neurofibromatosis. Histological and ultrastructural study]. PMID- 4196824 TI - [Clinical aspects of current typhoid-parathyphoid diseases based on data from the Ist hopital for Infectious Disease of the city of Yervan]. PMID- 4196825 TI - [Emergency prevention of experimental parathyphoid]. PMID- 4196826 TI - [Denitrification in Hydrogenomonas eutropha strain H 16]. PMID- 4196827 TI - [Biosynthesis of ribosomal RNA in the blue-green alga Anacystis nidulans]. PMID- 4196828 TI - [The indirect immunofluorescence test in the simultaneous diagnosis of Chagas' disease and toxoplasmosis]. PMID- 4196829 TI - (Effect of Lampit on experimental Trypanosoma cruzi infection in mice) PMID- 4196830 TI - Basic thalamic structure and function. Introductory remarks. PMID- 4196831 TI - Some principles of organization in the dorsal lateral geniculate nucleus. PMID- 4196832 TI - The medial geniculate body and associated thalamic cell groups: behavioral studies. PMID- 4196833 TI - On the organisation of the visual cortical projection to the pulvinar in Macaca mulatta. PMID- 4196834 TI - The connections of the dorsomedial nuclei. PMID- 4196835 TI - Chemosterilization of the tropical house mosquito Culex pipiens fatigans Wied.: laboratory and field cage studies. AB - Tris(1-aziridinyl)phosphine sulfide was found to be an excellent sterilant for male Culex pipiens fatigans. When male pupae were exposed to a 0.6% solution for 3 hours, the ensuing adults were rendered permanently sterile with no apparent reduction in their vigour or longevity based on laboratory and field cage studies. Females, however, exposed to the same dosage for the same length of time were partially fertile. PMID- 4196836 TI - WHO cooperative studies on the phage-typing of mycobacteria. 1. Phage lysis of Czechoslovak and Italian strains of Mycobacterium tuberculosis. AB - Although phage-typing of some pathogenic microbes-e.g., Escherichia coli and the genera Salmonella, Staphylococcus, and Streptomyces-is in routine use, little progress has yet been made in the phage-typing of mycobacteria, chiefly because mycobacteriophages possess a polyvalence that prevents the reliable identification of individual species of mycobacterium. Furthermore, laboratories cannot compare their results because they employ different methods and culture media and also because the phages used cannot be accurately identified. It has been shown that internationally reproducible results can be obtained for M. tuberculosis by selecting suitable mycobacteriophages and sensitive culture media, and by using a standardized technique of phage-typing. Under these conditions, phage lysis may be utilized to classify strains of M. tuberculosis. PMID- 4196837 TI - Management and marketing in health care. Some lessons for the United States from the British system. AB - The British health care system has been examined by sociologists, political scientists, and medical care specialists before, but in this presentation a section of the British health care system is viewed through the eyes of modern business management, particularly as to cost and consumer effectiveness. Examination of positive features as well as problems may be helpful in relation to some future health care delivery system in the United States. Cross fertilization between the disciplines of management and medicine has much to offer to the rapidly changing delivery of health care in the United States. PMID- 4196838 TI - Effects of prenatal nutrition upon pregnancy risk. PMID- 4196839 TI - Human placental lactogen in high-risk pregnancy. PMID- 4196840 TI - Hemolytic disease. PMID- 4196841 TI - Calories versus protein in children's nutrition. PMID- 4196842 TI - Hemorrhagic disease due to vitamin K deficiency in a premature infant: a syndrome which may resemble disseminated intravascular coagulation (DIC). PMID- 4196843 TI - Plumbism at the Green Parrot Goat Farm. PMID- 4196844 TI - Decreased performance behavior with carbaryl--an indication of clinical toxicity. PMID- 4196845 TI - Comparative study of peroxidases from the thyroid and the submaxillary gland of goat (Ca pra hiscus). PMID- 4196846 TI - Comparative studies of anti-A agglutinins from various snails of the genus Helix (Helix pomatia and Helix aspersa). PMID- 4196847 TI - Cell density as a selective parameter in Tetrahymena. PMID- 4196848 TI - Changes caused by air-drying and alcohol dehydration of spread insect sperm and fungal spore chromosome fibres. PMID- 4196850 TI - Occurrence of the genotype Cde-Cde in Papua New Guinea. PMID- 4196851 TI - Present status and future problems of medical care in Japan. PMID- 4196849 TI - Histochemical and biochemical studies on the localization and activity of lysosomal enzymes in fracture callus. PMID- 4196852 TI - Blood group genetic patterns and heterogeneity in New Guinea. PMID- 4196853 TI - Degenerative myelopathy in the aging German Shepherd dog: clinical and pathologic findings. PMID- 4196854 TI - Purification and properties of pyocin S2. PMID- 4196855 TI - Immunological cross-reaction between thiol proteases of plant origin: stem and fruit bromelains. PMID- 4196856 TI - Bioautography in paper and thin-layer chromatography and its scope in the antibiotic field. PMID- 4196857 TI - Gonococcal septicemia. PMID- 4196858 TI - A check-list of the species of the genus Leucocytozoon (Apicomplexa, Plasmodiidae). PMID- 4196859 TI - The resorption of cilia in Cyathodinium piriforme. PMID- 4196860 TI - East Coast fever of cattle: 60 Co irradiation of infective particles of Theileria parva. PMID- 4196861 TI - Sublethal cytotoxic effects of mercuric chloride on the ciliate Tetrahymena pyriformis. PMID- 4196862 TI - The conversion of phenylalanine to tyrosine in Tetrahymena pyriformis. PMID- 4196863 TI - [Comparisons of the IgG-IgA ratio in bronchial secretions and blood serum]. PMID- 4196865 TI - Influence of the implantation of Lactobacillus acidophilus in chicks on the growth, feed conversion, malabsorption of fats syndrome and intestinal flora. PMID- 4196864 TI - [Disodium cromoglycate in the treatment of asthma. Clinical and functional results. Value of the measurement of work of breathing]. PMID- 4196866 TI - Changes in relative frequencies of behaviors in pigtail monkeys (Macaca nemistrina) following dorsolateral frontal ablations. PMID- 4196867 TI - The effects of N,N-dimethyltryptamine on operant behavior in squirrel monkeys. PMID- 4196868 TI - [Gastric diverticula: contribution of 2 cases and review of the Spanish and foreign literature]. PMID- 4196869 TI - Electron optical investigations on the morphological alterations produced by subacute sclerosing panencephalitis (SSPE) virus in Cercopithecus aethiops (R 6 CA) kidney cells. PMID- 4196870 TI - Comparative investigations on immunodiffusion methods for detecting Australia antigen. PMID- 4196871 TI - Technique for making evident the precipitation bands obtained in immunodiffusion reactions gel. PMID- 4196872 TI - [Change in virulence of the saprophytic strain Mycobacterium smegmatitis ATCC 607 when mixed with Mycobacterium tuberculosis H37Rv in the mouse peritoneal cavity]. PMID- 4196873 TI - [Development of aspergillus flavus and production of aflatoxin B 1 in mayonnaise]. PMID- 4196874 TI - Sarcocystis in mice inoculated with toxoplasma-like oocysts from cat feces. AB - Sarcocysts morphologically similar to Sarcocystis muris were observed in mice after inoculation with Toxoplasma-like oocysts found in feces of a stray cat. Cats that were fed mice infected with the oocysts shed similar oocysts in their feces. Sarcocysts were found histologically in about 50 percent of mice inoculated with 40,000 or more oocysts and examined 42 days or longer after exposure. Most inoculated mice developed low Toxoplasma dye-test antibody titers 3 to 4 weeks after exposure, but Toxoplasma antibody was usually not detectable in infected cats. PMID- 4196875 TI - [Hydrolysis of the collagen from calf hide by a crystalline protease of Streptomyces griseus]. PMID- 4196876 TI - [Chromatographic study of the cationic and anionic proteases of Streptomyces griseus]. PMID- 4196877 TI - [Aspergillus flavus aminopeptidase]. PMID- 4196878 TI - [Glutamate decarboxylase activity of the limbic system structures of the brain]. PMID- 4196879 TI - [Effect of thiophosphamide on the cobalt level in rabbit organs]. PMID- 4196880 TI - [Experience in the experimental study of leprosy]. PMID- 4196881 TI - [Serum immunoglobulins in foot mycoses in children]. PMID- 4196882 TI - [Electron microscopic study of gonococcal microstructure in the urethral discharge of gonorrhea patients during penicillin and erythromycin therapy]. PMID- 4196883 TI - [Comparative study of serum proteins in acute and chronic schizophrenics and neurotics by the method of radial immunodiffusion Partigen]. PMID- 4196884 TI - Hypothalamo-pituitary interrelationships in thyroid pathology, with special reference to cretinism. PMID- 4196885 TI - Hypothalamic hypothyroidism: its possible relationshp to endemic goiter. PMID- 4196886 TI - Role of the placenta and of plasma hormone binding in the pathogenesis of cretinism. PMID- 4196887 TI - Alcohol preference. PMID- 4196888 TI - Studies of the development of alcohol addiction in infant monkeys. PMID- 4196889 TI - The reinforcing property of ethanol in the rhesus monkey. I. Initiation, maintenance and termination of intravenous ethanol-reinforced responding. PMID- 4196890 TI - Animal models of ethanol dependency. PMID- 4196891 TI - Biochemical and metabolic aspects of alcoholism. PMID- 4196892 TI - [Congenital spondyloepiphyseal dysplasia]. PMID- 4196893 TI - [Combined heart-skin disorders: the LEOPARD syndrome]. PMID- 4196894 TI - The affinity and temporal variation of isoelectric fractions of rabbit anti lactose antibody. PMID- 4196895 TI - Fatty acid synthetase activity in Euglena gracilis variety bacillarius. Characterization of an acyl carrier protein dependent system. PMID- 4196896 TI - Stopped-flow studies of high pH activity and acetazolamide inhibition of bovine carbonic anhydrase. Enzyme-catalyzed hydrolyses of 3-pyridyl and nitro-3-pyridyl acetates. PMID- 4196897 TI - The reaction of phenyl N-methylacetimidate with bovine serum albumin and bovine carbonic anhydrase. PMID- 4196898 TI - Preoperative irradiation for osteogenic sarcoma. PMID- 4196899 TI - Increased alkaline phosphatase in the tissues and hemolymph of the snail Biomphalaria glabrata infected with Schistosoma mansoni. PMID- 4196900 TI - The complex of ATP-dependent deoxyribonuclease from Bacillus subtilis with DNA and its thermostability. PMID- 4196901 TI - Carbon-13 nuclear magnetic resonance studies on thyrotropin-releasing factor and related peptides. PMID- 4196902 TI - Preparation of mammalian gametes and reproductive tract tissues for scanning electron microscopy. PMID- 4196904 TI - [Experiences in radiotherapy of vulvar carcinomas]. PMID- 4196903 TI - Lysis of lyophilized escherichia coli cells with egg-white lysozyme without ethylenediaminetetraacetic acid. PMID- 4196905 TI - Triple massive-dose drug therapy in combined treatment of advanced ovarian carcinoma. PMID- 4196906 TI - A method of correcting for collimator penetration by high energy gamma rays. PMID- 4196907 TI - Development of a single, simple in vitro thyroid function test. PMID- 4196908 TI - [Diagnosis and therapy of esophageal cancer--comparison of the clinical conditions before and after megavolt radiotherapy]. PMID- 4196909 TI - [Clinical nursing and its characteristics]. PMID- 4196910 TI - [Nursing of a patient with emotional problems due to extended hospitalization- problems of a patient with chronic kidney failure and his family]. PMID- 4196911 TI - [Efforts of the patient care team in diet therapy--problems of patients on hemodialysis]. PMID- 4196912 TI - [Prevention of infection at the site of the arteriovenous shunt--instructions for ambulatory hemodialysis patients on change of bandages]. PMID- 4196913 TI - [Nursing process in a case of epilepsy with psychiatric problems]. PMID- 4196914 TI - [Evaluation of complemental nursing care in cataract and stapedectomy patients]. PMID- 4196915 TI - [Tragedy of a young mother. 2. Guilt complex of a mother at the death of her child]. PMID- 4196916 TI - [Psychology in nursing. 3. On the special (VIP) patient]. PMID- 4196917 TI - [Transition in nursing and practical nursing manpower in various type hospitals with 50-99 beds]. PMID- 4196918 TI - [Hypertension, arteriosclerosis, angina pectoris and myocardial infarct]. PMID- 4196920 TI - [Hematological tests. 2. Bone marrow examination and other tests]. PMID- 4196921 TI - [Life science. 3. Life expressed in physiology of the cerebrum]. PMID- 4196919 TI - [Acute poisoning and its treatment]. PMID- 4196923 TI - [Group dynamics in nursing. 12. The structure of communication]. PMID- 4196922 TI - [Death and nursing. 3. Patient's right to know the truth. (1)]. PMID- 4196924 TI - [Geriatrics]. PMID- 4196925 TI - [History and current status of the International Council of Nurses]. PMID- 4196926 TI - [Assistance to aged patients in ambulation following craniotomy]. PMID- 4196928 TI - [Health guidance of expectant mothers in classroom instruction at the hospital outpatient clinic]. PMID- 4196927 TI - [Nursing of a child with leukemia]. PMID- 4196930 TI - [The two languages of nursing and medicine]. PMID- 4196929 TI - [Nursing of a patient with depression]. PMID- 4196931 TI - [Nursing of terminal patients. Nursing experience with a case of myasthenia gravis]. PMID- 4196932 TI - [Inconsistency of social welfare system and attitutdes of the poor. Observation on the conditions of a depressed mining area]. PMID- 4196933 TI - [Expenditures on social welfare. L. Annual increase of the government budget on social welfare]. PMID- 4196934 TI - [Arthropathies of the aged]. PMID- 4196935 TI - [Hemorrhagic diathesis and hemostasis]. PMID- 4196936 TI - [Leukemia and clinical diagnosis]. PMID- 4196937 TI - [Life science. 4. Physiologist's concept of life]. PMID- 4196938 TI - [Contract and responsibility in nursing relationship]. PMID- 4196939 TI - [Death and nursing. 4. The patient's right to know the truth. (2)]. PMID- 4196940 TI - [Group dynamics and nursing. 13. Effect of social power. Leadership. (1)]. PMID- 4196942 TI - [Pediatric nursing]. PMID- 4196941 TI - [Sociological study of food habits]. PMID- 4196943 TI - [Nursing of young depressed heart patients in intensive care units]. PMID- 4196944 TI - [Communication with tracheotomy patients in intensive care units]. PMID- 4196945 TI - [Speech training and training of daily activities of a child with aphasia following a cognition disorder]. PMID- 4196946 TI - [Team conference at the 1st ward of internal medicine, Okayama University. Maintenance of adequate nutrition in a patient with terminal cancer of the liver- efforts toward increased food intake]. PMID- 4196948 TI - [Fundamental problems in social welfare]. PMID- 4196947 TI - [On a visit to sites associated with Florence Nightingale]. PMID- 4196949 TI - [Expenditures in social welfare in Japan. 2. Social welfare budget compared with those of other countries]. PMID- 4196950 TI - [Surgery and the aged]. PMID- 4196951 TI - [Edema]. PMID- 4196952 TI - [Hemorrhagic diathesis]. PMID- 4196953 TI - [The concept of death in psychiatry]. PMID- 4196955 TI - [Death and nursing. 5. The concept of recovery]. PMID- 4196954 TI - [Professional attitude and private lives of the hospital staff in dealing with psychiatric patients]. PMID- 4196956 TI - [Group dynamics in nursing. 14. Basic function of the leader. (2)]. PMID- 4196957 TI - [Biological clocks]. PMID- 4196958 TI - The effects of antimalarial drugs on nucleic acid synthesis in vitro in Tetrahymena pyriformis. PMID- 4196959 TI - The distribution of l-thyroxine labeled with radioactive iodine-125 in the ears of squirrel monkeys. PMID- 4196960 TI - Study of efficiency of some modifications of medium B-2 for the primary cultivation of tubercle bacteria. PMID- 4196961 TI - Detection of vaccinia antigen and antibody by counterelectrophoresis. PMID- 4196962 TI - [Diagnosis and therapy of pyelonephritis in various age groups]. PMID- 4196963 TI - [Examination of the kininases in an oncolytic Clostridium (Strain M55ATCC13732) by means of chelate-forming agents]. PMID- 4196964 TI - [Duodenal diverticulum including the orifice of the papilla Vateri]. PMID- 4196965 TI - [Costs of surgery]. PMID- 4196966 TI - [Parenteral hyperalimentation]. PMID- 4196967 TI - [Evaluation of the meat of animals poisoned by sevin]. PMID- 4196968 TI - Mitotic activity of peritoneum in contact with a regenerating area of peritoneum. PMID- 4196969 TI - Variations in crypt cell cycle time and mitotic time in the small intestine of the rat. PMID- 4196970 TI - The pars distalis of the pituitary as a source of liver growth stimulating factors during liver regeneration. PMID- 4196971 TI - [Principles of therapy with high-energy rays]. PMID- 4196972 TI - [Attempted suicide with glibenclamide]. PMID- 4196974 TI - The influence of temperate bacteriophage phi105 on transformation and transfection in Bacillus subtilis. PMID- 4196973 TI - Myocardial steal produced by coronary vasocilation in chronic coronary artery occlusion. PMID- 4196975 TI - Lactose synthetase in mammary gland of the California sea lion. PMID- 4196976 TI - The effect of 2-mercaptoethanol (ME) and EDTA on the sub-species structure of horse liver alcohol dehydrogenase (LADH) in 8 M urea. PMID- 4196977 TI - The optical rotatory properties of poly- -D-glutamic acid. PMID- 4196978 TI - Conformational studies of anthrax polypeptide, subtilis polypeptide, and synthetic poly- -L-glutamic acid. PMID- 4196979 TI - [Treatment of Lyell's syndrome in a burn center]. PMID- 4196980 TI - The psychiatric nonhospital: a model for change. PMID- 4196981 TI - Control of pain and infection. PMID- 4196982 TI - Storage iron kinetics. 3. Study of desferrioxamine action by selective radioiron labels of RE and parenchymal cells. PMID- 4196984 TI - Insulin response to intravenous alimentation. PMID- 4196983 TI - Brain cholesterol. XVI. Incorporation of different precursors into baboon tissue sterol. PMID- 4196985 TI - Hypothalamic hypopituitarism. A case of panhypopituitarism with TSH and LH deficiency of hypothalamic origin. PMID- 4196986 TI - Cerebrospinal fluid transferrin II studies in ischemic disorders of the central nervous system. PMID- 4196987 TI - Antibiotic stability in solutions used for intravenous nutrition and fluid therapy. PMID- 4196988 TI - Successfully treated candida endophthalmitis in a child. PMID- 4196989 TI - [X-ray diagnosis of the orbit in the original x-ray picture]. PMID- 4196990 TI - [The orbital encephaloceles]. PMID- 4196991 TI - [Circadian rhythms and their role in human physiology and pathology]. PMID- 4196992 TI - Mixed lymphocyte reactivity in rhesus sibships. PMID- 4196993 TI - [Effect of the magnesium content in tRNA preparations of liver on their acceptor capability]. PMID- 4196994 TI - [Determination of the N-acetyl group of polyhedral protein in Borrelinavirus bombycis]. PMID- 4196995 TI - [Bioantioxidants as regulators of oxidative free radical processes at various stages of hepatic carcinogenesis]. PMID- 4196996 TI - [Long-term treatment of cyclothymia with lithium]. PMID- 4196998 TI - Electrical activity of single auditory nerve fibers. PMID- 4196997 TI - The efferent neural supply to the vertebrate ear. PMID- 4196999 TI - Noise-and drug-induced hearing loss in monkeys. PMID- 4197000 TI - [Enteral feeding with continuous low output in burned patients]. PMID- 4197002 TI - [Effect of the drug combination trimethoprim-sulfamethoxazole on the intestinal flora of man in short- and long-term administration]. PMID- 4197001 TI - HOE 296, a new antimycotic compound with a broad antimicrobial spectrum. Laboratory results. PMID- 4197003 TI - The synthesis and metabolic fate of 14 C-viminol, a new analgesic, in the rat and the dog. PMID- 4197004 TI - Immobilized enzymes: the catalytic properties of lactate dehydrogenase convalently attached to glass beads. PMID- 4197005 TI - Specific binding of ribonucleic acid by antiadenosine antibodies. PMID- 4197006 TI - Plasmic degradation of human fibrinogen. II. Further characterization of fragment D. PMID- 4197007 TI - Immunochemical studies on lactate dehydrogenase. PMID- 4197008 TI - Stabilization of Bacillus subtilis -amylase by amino group acylation. PMID- 4197009 TI - [Bronchoscopy in pulmonary tuberculosis with low bacillus levels]. PMID- 4197010 TI - [Value of various methods of homogenization of diagnostic materials by means of natrium hydroxide and trisodium phosphate]. PMID- 4197011 TI - "Photo-onycholysis" due to tetracycline. PMID- 4197012 TI - GENERAL ASPECTS OF INFECTION CONTROL IN THE OPERATING ROOM AND INTENSIVE CARE UNIT. PMID- 4197013 TI - New models in geriatrics and long-term care. PMID- 4197014 TI - Federal government involvement in training medical directors of long-term care facilities. PMID- 4197015 TI - Edema of the spinal cord following experimental impact trauma. PMID- 4197016 TI - Experimental local thalamic application of xylocaine through silicone rubber chemode. PMID- 4197017 TI - Localized renal parenchymal infections in children. PMID- 4197018 TI - Milk-of-calcium in caliceal diverticulum. PMID- 4197019 TI - A study on proteolytic oral microorganisms. PMID- 4197020 TI - [FSH and steroid hormone excretion in breast cancer during chemotherapy]. PMID- 4197021 TI - Metabolism of the hydroxyethylrutosides. Biliary and urinary excretion of 3',4',5 (hydroxyethyl- 14 C), 7-tetra-O-( -hydroxyethyl)-rutoside in rats and monkeys after parenteral administration. PMID- 4197022 TI - [Diagnostic errors from the viewpoint of the roentgenologist]. PMID- 4197023 TI - Protection from exercise-induced asthma by pre-exercise cromolyn sodium and its relationship to serum IGE levels. PMID- 4197024 TI - Thyrotropin releasing hormone: secretion and actions. PMID- 4197025 TI - The purification and properties of an extracellular protease from Aspergillus oryzae NRRL 2160. PMID- 4197026 TI - Iron binding of gastric mucins. PMID- 4197027 TI - Some biochemical properties of a cryomacroglobulin. PMID- 4197028 TI - The unstable oblique distal fibular fracture. PMID- 4197029 TI - Nucleotide metabolism in the whole blood of various vertebrates: enzyme levels and the use of high pressure liquid chromatography for the determination of nucleotide patterns. PMID- 4197030 TI - Clinical implications of Medicare upon an extended-care facility population. PMID- 4197033 TI - Connecticut dentists' views on expanded duty dental auxiliaries--preliminary report. PMID- 4197032 TI - Autologous tooth transplantations. PMID- 4197031 TI - [New local therapy of atrophic vaginitis]. PMID- 4197034 TI - Panoramic radiology--1973. PMID- 4197036 TI - Replantation case and technic. PMID- 4197035 TI - What is our condition to be? PMID- 4197037 TI - A surgical approach to the problem lower denture. PMID- 4197038 TI - Hydrotherapy in dentistry. PMID- 4197039 TI - Carbaryl synergism by substituted 1,3-benzodioxoles and related compounds and inhibition of mixed function oxidase. PMID- 4197040 TI - The marmoset periodontium in health and disease. PMID- 4197041 TI - [Comparative studies on Listeria and Erysipelothrix. I. Analysis of whole antigens]. PMID- 4197042 TI - [Comparative studies on Listeria and Erysipelothrix. II. Analysis of antigenic fractions]. PMID- 4197043 TI - [Economic aspects of family care]. PMID- 4197044 TI - Studies of the metabolism and distribution of prothrombin in healthy men with homologous 125 I-prothrombin. PMID- 4197045 TI - [Severe serogenic hemolytic anemia caused by anti-D fraction in factor VIII concentrate]. PMID- 4197046 TI - The effect of several tissue thromboplastins on the activation of the abnormal factor X (factor X Friuli). PMID- 4197047 TI - Identification of fibrinogen derivatives in plasma samples. PMID- 4197048 TI - Measurement of fibrin proteolysis in vivo by a radioactive fibrin-millipore tube technique. PMID- 4197049 TI - The rhesus monkey as a model for evaluation of the preservation of stored whole blood. PMID- 4197051 TI - A method for preservation of papainized and Rh-sensitized red cells. PMID- 4197050 TI - Selected types of frozen blood for patients with multiple blood group antibodies. PMID- 4197052 TI - Hemolytic disease of the newborn due to anti-Js a . PMID- 4197053 TI - Use of antibody synergism to screen human multiparous sera for lymphocytotoxins. PMID- 4197054 TI - Antisera to lysosomes. Effect on allograft rejection. PMID- 4197055 TI - [Separation of the crystalline complex of Streptomyces griseus proteases and a study of its enzymatic composition]. PMID- 4197056 TI - [Amination and transamination processes in cell-free extracts of tuberuculosis mycobacteria]. PMID- 4197057 TI - [Hippocampus]. PMID- 4197058 TI - [Roentgenological diagnosis of the duodenal bulb diverticula]. PMID- 4197059 TI - [Convulsions in childhood]. PMID- 4197060 TI - [Studies on the autoregulation of cerebrovascular circulation. I. Acute pressure induced changes of the cerebral vascular resistance in normo- and hypercapnia]. PMID- 4197061 TI - [Role of the limbic system in physiological determinism of emotional and social reactivity]. PMID- 4197062 TI - Central venous alimentation. PMID- 4197063 TI - A specific method for the quantitative determination of -glucose-1-phosphate. PMID- 4197064 TI - A compilation of amino acid analyses of proteins. IV. Residues per thousand residues series 1. PMID- 4197066 TI - EDTA prevents the photocatalyzed destruction of the products of catecholamine oxidation. PMID- 4197065 TI - Precipitation of RNA, DNA, and nucleoprotein particles from very dilute solutions. PMID- 4197067 TI - Comparison of NCS solubilization and a wet combustion technique for 14 C measurement in dried biological tissues. PMID- 4197068 TI - THR (lopremone): psychobiological responses of normal women. I. Subjective experiences. PMID- 4197069 TI - THR (lopremone): psychobiological responses of normal women. II. Pituitary thyroid responses. PMID- 4197070 TI - Methaqualone withdrawal. PMID- 4197071 TI - Toxicological and teratological studies of 4((5-chloro-2-oxo-3 benzothiazolinyl)acetyl)-1-piperazine ethanol hydrochloride (Tiaramide hydrochloride), an anti-inflammatory drug. PMID- 4197072 TI - [Studies on the microbial resistance to the drug combination sulfamethoxazole trimethroprim with special reference to enterococci]. PMID- 4197073 TI - Kinetic properties of microsomal UDP-glucuronyltransferase. Regulation by metal ions. PMID- 4197074 TI - Organelle formation in the presence of a protease inhibitor. PMID- 4197075 TI - The use of buoyant density profiles in determining the length and spacing of repeated sequences in DNA. PMID- 4197076 TI - Membrane proteins of Rhodopseudomonas spheroides. IV. Characterization of chromatophore proteins. PMID- 4197077 TI - Uptake of calcium in chromaffin granules of bovine adrenal medulla stimulated in vitro. PMID- 4197078 TI - Transcription of Tetrahymena mitochondrial DNA in vivo. PMID- 4197079 TI - Presence of ergosterol in light-grown and dark-grown Euglena gracilis Z. PMID- 4197080 TI - Diamine oxidase in rabbit liver. 1. Assay conditions and subcellular localization. PMID- 4197081 TI - Diamine oxidase in rabbit liver. 2. Submicrosomal distribution. PMID- 4197082 TI - Dna synthesis in isolated HeLa nuclei. A system for continuation of replication in vivo. PMID- 4197083 TI - [Complete intravenous nutrition in children]. PMID- 4197084 TI - Studies for the effect of some dietary factors prevalent in the oasis on the rate of growth and serum protein fractions of experimental animals. PMID- 4197085 TI - Luetic deafness. PMID- 4197086 TI - A model for experimental vasomotor rhinitis. PMID- 4197087 TI - [Interpretation of the results of a complex radioisotope study of thyroid gland function during "block" by iodine and bromine preparations]. PMID- 4197088 TI - [Radiation therapy of cancer of the mucous membrane of the maxillary alveolar process]. PMID- 4197089 TI - Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver. AB - The CO-difference spectrum of microsomes from rats treated with the polychlorinated biphenyls mixture, Aroclor 1254, has an absorption maximum at 448 nm. With ethylisocyananide as the ligand for reduced microsomes, Aroclor 1254 treatment causes a shift in the 455-nm peak to 453 nm and increases the ratio of absorbance of 455 nm to that at 430 nm from 0.53, obtained with untreated rats, to 1.24. These findings are similar to those seen in rats treated with the polycyclic hydrocarbon, 3-methylcholanthrene, but differ from those that characterize cytochrome P-450 in control or phenobarbital-treated rats. Aroclor 1254 treatment results in a tripling of cytochrome P-448 content and a 10-fold increase in benzo-[a]pyrene hydroxylation. However-unlike 3-methylcholanthrene, but like the phenobarbital type of inducing agents-Aroclor 1254 treatment causes a significant enhancement of ethylmorphine N-demethylase. These data suggest that Aroclor 1254-induced cytochrome P-448 may be catalytically different from the 3 methylcholanthrene-induced P-448 or that the hemoprotein(s) induced by Aroclor 1254 may be a mixture of cytochromes P-448 and P-450 exhibiting catalytic properties of both cytochromes. PMID- 4197090 TI - Independent control of ribosomal gene replication in polytene chromosomes of Drosophila melanogaster. AB - The saturation values for ribosomal RNA hybridization have been determined for DNA from diploid and polytene tissues of Drosophila melanogaster. These values have been measured in XO and XX larvae which have, respectively, one and two nucleolus organizers in the diploid chromosome set. The results show that (1) in diploid cells the ribosomal (r)DNA is present in amounts proportional to the number of nucleolus organizers, (2) in polytene cells the rDNA is under replicated with respect to the euchromatic DNA, and (3) in polytene cells the amount of rDNA is independent of the diploid number of nucleolus organizers. These observations suggest that somatic variations in rDNA content may involve independent polytenization of the nucleolus organizer without change in the number of ribosomal cistrons per organizer. The independent polytenization of rDNA is proposed as the chromosomal explanation for the relative increase in rDNA in flies of the XO constitution. PMID- 4197091 TI - Conformational analysis of thyrotropin releasing factor. AB - Conformational energy calculations on thyrotropin releasing factor and on several of its analogues indicate that the central histidyl residue of the native molecule is in an extended conformation. Some derivatives (with a reduced biological activity) have an altered conformation. Since some substitutions leave the conformation unchanged but alter the biological activity, these substitutions must involve the sites responsible for binding of the hormone to its receptor. PMID- 4197092 TI - Regulation of the -methylgalactoside transport system and the galatose-binding protein by the cell cycle of Escherichia coli. AB - The synthesis of the periplasmic galactose-binding protein of E. coli is regulated by events occurring during its cell cycle, and proceeds in synchronized cells for only a short period after cell division is completed. Transport activity mediated by the beta-methylgalactoside transport system follows closely the synthesis pattern of the binding protein.A mutant, E. coli BUG-6, exhibits temperature-sensitive cell division [Reeve et al. (1970) J. Bacteriol. 104, 1052 1064], synthesizing galactose-binding protein at the permissive but not at the nonpermissive temperature. Galactose-binding protein synthesized at the permissive temperature is not degraded after the culture is shifted to the nonpermissive temperature. Polyacrylamide gel electrophoresis of the periplasmic proteins of BUG-6 grown at the permissive and nonpermissive temperatures suggests that several, but not all, periplasmic proteins are subject to the same regulatory control by the cell cycle as the galactose-binding protein. PMID- 4197094 TI - [SMON and chinoform]. PMID- 4197093 TI - Studies on in vitro DNA synthesis. Purification of the dna G gene product from Escherichia coli. AB - varphiX174 DNA-dependent dNMP incorporation is temperature-sensitive (ts) in extracts of uninfected E. coli dna A, B, C, D, E, and G ts strains. DNA synthesis can be restored in heat-inactivated extracts of various dna ts mutants by addition of extracts of wild-type or other dna ts mutants. A protein that restores activity to heat-inactivated extracts of dna G ts cells has been extensively purified. This protein has also been purified from dna G ts cells and is thermolabile when compared to the wild-type protein. The purified dna G protein has a molecular weight of about 60,000, is insensitive to N ethylmaleimide, and binds poorly to DNA. It does not stimulate heat-inactivated crude extracts of dna B, C, D, or E ts cells and lacks detectable RNA and DNA polymerase activities. PMID- 4197095 TI - Attempted induction of sarcoma in a Cape Chacma baboon with the Snyder-Theilen feline sarcoma virus. PMID- 4197096 TI - [Studies of a new chemical dentin and pulp protective material (rapid-Lasul)]. PMID- 4197097 TI - [Diverticulosis of the small intestine]. PMID- 4197098 TI - [Mechanism of nitroglycerine effect from the aspect of myocardial contractility. Experimental animal studies on the isolated human ventricular myocardium]. PMID- 4197099 TI - [Intraepithelial multiplication of Enterobacteriaceae and its role in the pathogenesis of dysentery and intestinal coli-infection]. PMID- 4197100 TI - [Pseudomonas aeruginosa bacteriophages. I. Isolation, morphology of the negative spots, range of lytic action and the antigenic properties of the bacteriophages]. PMID- 4197101 TI - [Methods for detecting viral contaminants in live rickettsial vaccines obtained from chick embryos]. PMID- 4197102 TI - [Ticks as the media for a Rickettsia habitatl (a survey of the literature)]. PMID- 4197103 TI - [Electron microscope study of division in Bac. subtilis]. PMID- 4197104 TI - Features of cerebellar morphology and organization. PMID- 4197105 TI - Multiple sclerosis: immunoglobulin alterations related to different clinical parameters. PMID- 4197106 TI - The innervation of the cerebral arteries in the monkey. PMID- 4197107 TI - Meningococcal infections. PMID- 4197108 TI - Capillary basement membranes and diabetic microangiopathy. PMID- 4197109 TI - Total parenteral nutrition. PMID- 4197110 TI - Axon diameter and myelin thickness. Unusual relationships in dorsal root ganglia. PMID- 4197111 TI - [Intracardiac conduction disorders. Attempt at classification]. PMID- 4197112 TI - [Temporary circulatory assistance by pulsatile veno-arterial shunt. Results and current limitations of its clinical use]. PMID- 4197113 TI - [Measurement of cardiac output by the thermodilution method. Definition of a new apparatus]. PMID- 4197114 TI - [Recording of the electrical activity of auriculo-ventricular conduction tissue in ventricular tachycardia]. PMID- 4197115 TI - [Hazards of demand pacemaking during the acute stage of myocardial infarct]. PMID- 4197116 TI - [Slow ventricular tachycardia. Value of His bundle recording in their diagnosis]. PMID- 4197117 TI - [Angiographic study of the coronary arteries during exploration of nonobstructive myocardiopathies]. PMID- 4197118 TI - [Anterior left hemiblocks simulating antero-septal infarction. Value of sequential precordial leads]. PMID- 4197119 TI - [Measurement of coronary blood flow with xenon 133 during selective coronarographies. Preliminary study]. PMID- 4197120 TI - [Valsalva's maneuver as an over-all test of myocardial function]. PMID- 4197121 TI - Study of the extracellular polysaccharides produced by a blue-green alga, Anabaena flos-aquae A-37. PMID- 4197122 TI - [Occurrence of bacteriochlorophyll a P and a gin strains of all species of the Rhodospirillaceae]. PMID- 4197123 TI - Purification and properties of two forms of staphylococcal toxin. PMID- 4197124 TI - Water and ions in muscles and model systems. PMID- 4197125 TI - Drug-induced reinstatement of amphetamine self-administration behaviour in monkeys. PMID- 4197126 TI - [Incorporation of tritiated thymidine in renal cell cultures treated with Gerovital H 3 ]. PMID- 4197127 TI - [Several current problems in chemotherapy of tuberculosis]. PMID- 4197128 TI - Fundamentals of infant resuscitation. PMID- 4197129 TI - Problems in the determination of polychlorinated biphenyls. PMID- 4197130 TI - Decrease in pulmonary diffusing capacity during lipid infusion in healthy men. PMID- 4197131 TI - The interaction of radioactive initiation factor IF-2 with ribosomes during initiation of protein synthesis. PMID- 4197132 TI - The subunits of human pituitary thyroid-stimulating hormone. Isolation, properties, and composition. PMID- 4197133 TI - Subunit heterogeneity of thyroglobulin. PMID- 4197134 TI - Meningonema peruzzii gen. et sp. n. (Nematoda: Filarioidea) from the central nervous system of African monkeys. PMID- 4197135 TI - The complete development of the sporogonous stages of Hepatozoon rarefaciens cultured in a Culex pipiens cell line. PMID- 4197136 TI - Sarcocystis in dogs and its probable transmission from cattle. PMID- 4197137 TI - [Incidence of Australia antigen and the corresponding antibody in the Moroccan environment (3.680 serums). Preliminary results]. PMID- 4197139 TI - The malabsorption syndrome. PMID- 4197138 TI - Evolving concepts of thyroid function. PMID- 4197140 TI - Action of levallorphan: macromolecular synthesis and cell division. PMID- 4197141 TI - Analogues of fusaric (5-butylpicolinic) acid as potent inhibitors of dopamine hydroxylase. PMID- 4197142 TI - Levodopa and melanoma. PMID- 4197143 TI - [Diagnosis of jaundice caused by obstruction of the extra-hepatic bile ducts. Study of Au serum lipids and lipoproteins]. PMID- 4197144 TI - A new understanding of hepatitis. PMID- 4197145 TI - [Precipitation reaction of Clq and rheumatoid factor with denatured IgG in agarose gel]. PMID- 4197146 TI - [Pituitary response to TRH (thyrotropin releasing hormone) in normal persons. Use of TRH test in thyroid diseases]. PMID- 4197147 TI - Induction of mating behavior in rats by luteinizing hormone-releasing factor. AB - Ovariectomized female rats treated with estrogen, in dosages too low to provoke mating, displayed this behavior when given subcutaneous injections of synthetic luteinizing hormone-releasing factor (LRF) 48 hours later. Two hours after the injection of LRF, components of female sexual behavior appeared. The lordosis reflex followed mounting by the male, and darting and hopping behavior was quite prevalent. On the other hand, treatment with estrogen followed by luteinizing hormone, follicle-stimulating hormone, or thyrotropin-releasing factor did not induce copulatory behavior. The results suggest that LRF may play a role in induction of mating behavior. PMID- 4197148 TI - Somatic evoked response recording: an adequate test of deafferentation? PMID- 4197149 TI - [Problems in the ambulatory care of kidney diseases]. PMID- 4197150 TI - [Histological and enzyme-histochemical studies on the effect of prolonged testosterone administration on the epiphyseal cartilage of rats]. PMID- 4197151 TI - Electron microscopic study of the endothelium of stored and cryopreserved monkey corneas. PMID- 4197152 TI - Osteomyelitis in hemodialysis patients. PMID- 4197153 TI - Diabetic ketoacidosis associated with mumps virus infection. Occurrence in a patient with macroamylasemia. PMID- 4197154 TI - How effective will national health insurance be? PMID- 4197155 TI - Bilateral hilar adenopathy. PMID- 4197156 TI - Immunochemical studies of AMP:pyrophosphate phosphoribosyltransferase from normal and Lesch-Nyhan subjects. PMID- 4197157 TI - Involvement of a carboxyl group in the active site of Bacillus cereus 569-H penicillinse ( -lactamase I). PMID- 4197158 TI - Inhibition of phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase by uridine diphosphate N-acetylmuramyl peptides. PMID- 4197159 TI - The effect of temperature, age and density of gametocytes, and changes in gas composition on exflagellation of Leucocytozoon simondi. PMID- 4197160 TI - The fine structure of Leucocytozoon simondi. VI. Hepatic schizogony. PMID- 4197161 TI - Corynebacterium diphtheriae in a patient with multiple trauma. PMID- 4197162 TI - Short- and long-term prophylaxis with cromolyn sodium in chronic asthma. PMID- 4197163 TI - A clinical index of disability due to chronic asthma tested during a trial of cromolyn sodium treatment. PMID- 4197164 TI - An evaluation of bacterial contamination of ventilator humidifying systems. PMID- 4197165 TI - Replication pattern and quinacrine fluorescence of the chromosomes of a CV-1 derived African green monkey cell line. PMID- 4197166 TI - Complementation analysis of male fertility among the segregation distorter chromosomes of Drosophila melanogaster. AB - The fecundities of 55 genotypes of the form SD(i)/SD(j) generated by 11 different SD chromosomes have been examined. Five of the genotypes are lethal The fecundities of the rest fall into a pattern of fertility and sterility that is highly suggestive of intracistronic complementation. The complementation leading to male fertility is only partial complementation: the fecundity of most fertile genotypes is less than half that of controls. The three components of the SD system, the Sd locus, the Ac locus, and the modifiers in 2R, were examined separately, and it appears that the complementation is a phenomenon associated with the Sd locus. A hypothesis of the molecular events involved in segregation distortion is formulated in the light of these observations. The model is based on the assumption that the Sd locus produces a multimeric molecule that regulates the activity of the Ac(=Rsp) locus during spermatogenesis. PMID- 4197167 TI - Meiotic behavior of asymmetric dyads in the male Drosophila. AB - Crossing over in the interstitial region of the heterozygous V(4) translocation in Drosophila melanogaster generates asymmetric dyads each consisting of a shorter and a longer chromatid. It was shown previously that in the female the shorter is recovered preferentially (Zimmering 1955); the present work suggests that the same occurs in the male as well. The mechanism in the female is envisioned as involving the non-random inclusion of the shorter chromatid into the functional egg (Novitski 1951); in the male, the two formal possibilities appear to be (1) that some proportion of sperm carrying the longer chromatid derived from an asymmetric dyad undergoes dysfunction, or (2) the longer chromatid is preferentially included into regularly-produced nonfunctional sperm, the nonfunctionality set up at the second division and distinguishing second division daughter cells. PMID- 4197168 TI - Analysis of carbamates as fluorescent 1-dimethylamino-naphthalene-5-sulfonate esters. PMID- 4197169 TI - Trace analysis and fundamental studies by plasma chromatography. PMID- 4197170 TI - Culture for gonorrhea in asymptomatic college women. PMID- 4197171 TI - [Effects of B12 deficiency on protein RNA and DNA contents of Euglena gracilis Z cells in synchronous culture]. PMID- 4197172 TI - [Cyclic structural changes in the nucleus, nucleolus and mitochondria of Euglena gracilis Z in synchronous culture]. PMID- 4197173 TI - [Restoration metabolism of isolated muscles of Amphibia]. PMID- 4197174 TI - [Analysis of folates in fetuses of control rats and of rats with folic acid deficiency]. PMID- 4197175 TI - [Study of delayed current in myocardial fibers of the monkey using the double sucrose-gap method]. PMID- 4197176 TI - [Cytochemical study of haemogregarines from reptiles of Armenia. II. Changes in hemoglobin and total protein levels in the erythrocytes of rock lizards infected with haemogregarines]. PMID- 4197177 TI - Spectral sensitivity in primates: a comparative study. PMID- 4197178 TI - [Neonatal listeriosis]. PMID- 4197179 TI - [Fats in trans-venous feeding]. PMID- 4197180 TI - [Use of lactic enzymes in non-bacterial gastroenteritis]. PMID- 4197181 TI - [Therapeutic results in primary carcinoma of the vulva]. PMID- 4197182 TI - Excretion of urate by the kidneys of Cebus monkeys: a micropuncture study. PMID- 4197183 TI - Plasma kallikrein-kinin system in nonmammalian blood: evolutionary aspects. PMID- 4197184 TI - Uricosuric effect of benziodarone in man and laboratory animals: a comparative study. PMID- 4197185 TI - Nature of the uricosuric action of benziodarone. PMID- 4197186 TI - Changes of plasma glucose and insulin during defense reactions in monkeys. PMID- 4197187 TI - Suction flow drainage in head and neck surgery. A new principle for postoperative suction drainage. PMID- 4197188 TI - Recent advances in the physiology and pathophysiology of potassium excretion. PMID- 4197189 TI - Release of thyroid stimulating hormone from chick anterior pituitary glands by thyrotropin releasing hormone (TRH). PMID- 4197190 TI - Polygammaglutamyl metabolites of methotrexate. PMID- 4197191 TI - A novel technique for the preparation of transport-active membrane vesicles from Pseudomonas aeruginosa: observations on gluconate transport. PMID- 4197192 TI - The synaptic organization in the inferior pulvinar of the rhesus monkey (Macaca mulatta). PMID- 4197194 TI - Radioimmunoassay of testosterone during fetal development of the rhesus monkey. PMID- 4197193 TI - Sympathomimetic anesthetics. PMID- 4197195 TI - Comparison of baboon and human placental lactogens. PMID- 4197196 TI - [Our experiences in the therapy of epilepsy with Morfolep]. PMID- 4197197 TI - [Oto-neurologic picture of Recklinghausen's disease]. PMID- 4197198 TI - [Generalized neurofibromatosis (Recklinghausen's disease) in a small child]. PMID- 4197199 TI - Prenylamine lactate in angina pectoris. PMID- 4197200 TI - Effect of nitrogen mustard and corticoids on experimentally produced villonodular synovitis. PMID- 4197201 TI - Dimethyl sulfoxide in the treatment of experimental brain compression. PMID- 4197202 TI - Shigellosis in rhesus monkeys in quarantine. PMID- 4197203 TI - Use of CT1341 anaesthetic ("Saffan") in monkeys. PMID- 4197204 TI - The cerebral autonomic nervous system. A proposed physiologic function and pathophysiologic response in subarachnoid hemorrhage and in focal cerebral ischemia. PMID- 4197205 TI - [Level of the C1 esterase inhibitor and hemolytic activity of C1 in hypertensive and uremic patients]. PMID- 4197206 TI - [Enzymology and pesticide poisoning]. PMID- 4197207 TI - Correlation between lethality and DNA single-strand breaks in Bacillus subtilis cells treated with N-methyl-N'-nitro-N-nitrosoguanidine. PMID- 4197208 TI - Central neurogenic control of cerebral circulation. Effects of intravertebral injection of pyrithioxin on cerebral blood flow and metabolism. PMID- 4197209 TI - Myasthenia gravis. Cellular response to basic myelin protein compared with cellular and humoral immunity to muscle antigens. PMID- 4197210 TI - Pulp capping in monkeys with a calcium-hydroxide compound, an antibiotic, and a polycarboxylate cement. PMID- 4197211 TI - [Effects of silimarine on the hepatotoxic capacity of butter-yellow combined with a rice diet, in rats]. PMID- 4197212 TI - [Solitary neurofibromatosis of the small intestine as the sole manifestation of von Recklinghausen's disease]. PMID- 4197213 TI - Mechanisms of cholesterol accumulation in atherosclerotic lesions. PMID- 4197214 TI - [Tibio-tarsal denervation in post-traumatic arthrosis]. PMID- 4197215 TI - Nutrition and the liver. PMID- 4197216 TI - Growth and growth hormone in protein calorie malnutrition. PMID- 4197217 TI - [Changes in protein metabolism in patients with stomach cancer operated on with the use of autohemotransfusion]. PMID- 4197218 TI - [Preliminary data on the treatment of gastroduodenal ulcers by feeding through the small intestine via a catheter]. PMID- 4197220 TI - Serological analysis of wheat striate mosaic virus and its soluble antigen. PMID- 4197221 TI - The role of sensitizing antibody in the neutralization of equine arteritis virus by complement or anti-IgG serum. PMID- 4197222 TI - The fate of sensitized equine arteritis virus following neutralization by complement of anti-IgG serum. PMID- 4197223 TI - Viral RNA synthesis in measles virus-infected cells. PMID- 4197224 TI - [Sparial analysis in monkeys of various ages following extirpation of the parietal region of the cerebral cortex]. PMID- 4197225 TI - [Functional characteristics of the hippocampus in lower monkeys]. PMID- 4197226 TI - Technical solution of the problem of investigation of instrumental conditioned reflexes with intragastric reinforcement. PMID- 4197227 TI - Plasma and red blood cell amino acids of Egyptian children suffering from protein -calorie malnutrition. PMID- 4197228 TI - Evaluation of small-scale nutrition programs. PMID- 4197229 TI - Mode of action of rifampin on mycobacteria. I. Electron microscopic study of the effect of rifampin on Mycobacterium tuberculosis. PMID- 4197231 TI - The relative immunogenicity of virulent and attenuated strains of tubercle bacilli. PMID- 4197230 TI - Correlation of in vitro and in vivo kinetics with clinical use of isoniazid, ethambutol, and rifampin. PMID- 4197232 TI - The fate of virulent and attenuated Mycobacteria in guinea pigs infected by the respiratory route. PMID- 4197233 TI - Clearance and inactivation of the vegetative and spore forms of Bacillus subtilis Var niger in rat lungs. PMID- 4197234 TI - Incidence of pulmonary tuberculosis. PMID- 4197235 TI - [The ethmoid labyrinth. I. Systemic concepts of mammalian ethmoid turbinates]. PMID- 4197236 TI - A note on the toxic effects of tricresylphosphate on spinal ganglion of slow loris (Nycticebus cougang cougang). PMID- 4197237 TI - Wheat leaf RNA polymerases. 3. Purification of the soluble RNA polymerase. PMID- 4197238 TI - Permeability of the duodenum of the toad to non-electrolytes. PMID- 4197239 TI - Prognosis of acute renal failure. PMID- 4197241 TI - Administration of disodium cromoglycate to young children. PMID- 4197240 TI - Australia (hepatitis-associated) antigen in patients attending a venereal disease clinic. AB - A total of 1,650 patients attending the venereal disease department at St. Mary's Hospital, London, have been tested for Australia antigen. Twenty-three positive results were obtained, or 1.39%, which is more than 10 times the rate noted by others in blood donor populations in the U.K. and U.S.A. The positive rates among female patients and European male heterosexual patients were 0.36% and 0.19% respectively. High rates were obtained for homosexual patients (3.8%) and non European heterosexual patients (3.1%). The reasons for the higher rates found in these groups merit further study. PMID- 4197242 TI - Characterization and partial purification of -hydroxybutyrate dehydrogenase from sporulating cells of Bacillus cereus T. PMID- 4197243 TI - A cluster of mutations determining erythromycin resistance in Bacillus subtilis. PMID- 4197244 TI - Extracellular carbohydrate antigens from some non-pathogenic Neisseria species. PMID- 4197246 TI - Immunological reactions of Mycobacterium leprae and Mycobacterium lepraemurium grown in cayman. PMID- 4197245 TI - The immunological analysis of soluble human leukemia associated antigens. PMID- 4197247 TI - Improved techniques for assessment of plasma lipoprotein patterns. I. Precipitation in gels after electrophoresis with polyanionic compounds. PMID- 4197248 TI - Immunochemical identification of prostatic tissue-specific acid phosphatase. PMID- 4197249 TI - Immunochemical identification of prostatic tissue-specific acid phosphatase. PMID- 4197250 TI - RIA: an historical note. PMID- 4197251 TI - Objective assessment of a bronchodilator drug combination in asthmatic outpatients. PMID- 4197253 TI - A study of the selectivity of action of oxyphencyclimine hydrochloride on gastric secretion. (selectivity of oxyphencyclimine). PMID- 4197252 TI - Lidoflazine and angina pectoris: a placebo-controlled double-blind study. PMID- 4197254 TI - Effects of hydrochlorothiazide in hypertensive patients and the need for potassium supplementation. PMID- 4197255 TI - A long-term follow-up of fluphenazine enanthate treatment. PMID- 4197256 TI - Milipertine: an early evaluation in severely ill schizophrenics. PMID- 4197257 TI - SCH-12041 in the treatment of acute schizophrenic patients. PMID- 4197258 TI - A double-blind comparison of AL-1021 and chlorpromazine in hospitalized schizophrenics. PMID- 4197259 TI - [Concomitant symptoms in cheilognathopalatoschisis in patients of the Thallwitz Clinic]. PMID- 4197260 TI - In vitro studies of trans- and intraepithelial potentials of the cornea. PMID- 4197262 TI - Kinines and pain in "dry socket". PMID- 4197261 TI - Recent studies on the nature and function of the corneal endothelial barrier. PMID- 4197263 TI - Renal viability and oxygen consumption measurements during preservation. PMID- 4197264 TI - Glutamic acid decarboxylase in spores of Bacillus megaterium and its possible involvement in spore germination. AB - Spores of Bacillus megaterium were examined for glutamic acid decarboxylase (GAD). Although dormant spores showed no GAD activity, spores given sonic treatment and heat-activated spores had high activities when assayed for this enzyme. Several parameters of GAD in heat-activated spores were examined. The effects of KCN, NaN(3), 2,4-dinitrophenol, and KF on GAD activity were examined. Only KCN was an effective inhibitor of GAD activity in heated spores and was also shown to be the only effective inhibitor of GAD activity in vegetative bacteria. Similar patterns of inhibition were obtained with GAD activity and with spore germination, KCN being the only effective inhibitor of both, although at different concentrations. Spore GAD activity in heat-activated spores showed a loss with storage at 4 C; on the other hand, storage at 25 C was not accompanied by a loss, but, to the contrary, showed an increase in GAD activity of about 30%. A comparison of GAD activity at different times during germination, growth, and sporulation showed it to be highest in freshly germinated spores. Although vegetative cells contained GAD activity, the level in log-phase cells was approximately one-half the level obtained with freshly germinated spores. Heat activated mutant spores with a requirement of gamma-aminobutyric acid for germination gave no GAD activity. GAD activity appeared in mutant spores after germination and increased to levels comparable to parent spores after 9 min of germination. PMID- 4197265 TI - Deoxyribonucleic acid synthesis and deoxynucleotide metabolism during bacterial spore germination. AB - Deoxyribonucleic acid (DNA) synthesis during germination of Bacillus megaterium spores takes place in two stages. In stage I (0-55 min) DNA synthesis is slow and there is no detectable net synthesis, whereas in stage II (from 55 min on) the rate of synthesis is much faster and net DNA synthesis occurs. Deoxyribonucleotide pool sizes match the rates of DNA synthesis in stages I and II. The level of deoxyribonucleotide triphosphates is not correlated with the level of deoxyribonucleotide kinases, but rather with that of ribonucleotide reductase activity. PMID- 4197266 TI - Location of the SPO2 attachment site and the bryamycin resistance marker on the Bacillus subtilis chromosome. AB - The attachment site on the Bacillus subtilis chromosome for the lysogenic bacteriophage SPO2 has been mapped by PBS1-mediated transduction and was found to be between spc-2 and lin-2, showing 90% linkage to the former and 30% linkage to the latter marker. In the course of these studies the bry-2 marker was mapped between the cysA14 and str-1 loci. PMID- 4197267 TI - Osmotic behavior of bacterial protoplasts: temperature effects. AB - Among protoplasts released from cells of Bacillus megaterium grown at 20, 30, or 37 C, osmotic swelling in NaCl solution at a given external osmotic pressure was greatest for protoplasts from cells grown at 20 C and least for protoplasts from cells grown at 37 C. Protoplasts from cells grown at lower temperaturs were also less stable to osmotic shock and lysed at higher external osmotic pressures than did protoplasts from cells grown at higher temperatures. But for cells grown at any one temperature, osmotic stabilization was itself temperature dependent so that the higher the ambient incubation temperature, the higher the osmotic pressure needed to prevent lysis of a given fraction of the input protoplast population. However, comparison of the osmotic stability of protoplasts from cells grown at different temperatures at various ambient incubation temperatures revealed that, except at 5 C where no differences were discerned, protoplasts from cells grown at lower temperatures still lysed at higher osmotic pressures than did those from cells grown at higher temperatures. The apparent internal osmolality (28 to 31 atm) did not vary significantly among whole cells from the three growth temperatures. Therefore, the observed differences in osmotic behavior could not be attributed to changes in internal osmotic pressure. Rather, it seemed likely that the differences were due to changes in membrane properties. PMID- 4197269 TI - Oxygen toxicity and the superoxide dismutase. AB - Oxygen caused an increase in the amount of superoxide dismutase in Escherichia coli B but not in Bacillus subtilis. E. coli B cells, induced by growth under 100% O(2), were much more resistant to the lethal effects of 20 atm of O(2) than were cells which contained the low uninduced level of this enzyme. In contrast, B. subtilis, which could not respond to O(2) by increasing its content of superoxide dismutase, remained equally sensitive to hyperbaric O(2) whether grown under 100% O(2) or areobically. The catalase in these organisms exhibited a reciprocal response to oxygen. Thus, the catalase of E. coli B was not induced by O(2), whereas that of B. subtilis was so induced. These results are consistent with the view that superoxide dismutase is an important component of the defenses of these organisms against the toxicity of oxygen, whereas their catalases are of secondary importance in this respect. The ability of streptonigrin to generate O(2) (-), by a cycle of reduction followed by spontaneous reoxidation, has been verified in vitro. It is further observed that E. coli B which contain the high induced level of superoxide dismutase were more resistant to the lethality of this antibiotic, in the presence of oxygen, than were E. coli B which contained the low uninduced level of this enzyme. This difference between induced and uninduced cells was eliminated by the removal of O(2). These results are consistent with the proposal that the enhanced lethality of streptonigrin under aerobic conditions may relate to its in vivo generation of O(2) (-) by a cycle of reduction and spontaneous reoxidation. In toto, these observations lend support to the hypothesis that O(2) (-) is an important agent of oxygen toxicity and that superoxide dismutase functions to blunt the threat posed by this reactive radical. PMID- 4197268 TI - Isolation of two acetyl esterases from extracts of Bacillus subtilis. AB - Acrylamide gel electrophoresis of crude cellular extracts of Bacillus subtilis revealed the presence of two acetyl esterases. Esterase A, the slower migrating enzyme, was found to be present in both vegetative and sporulating cells, whereas esterase B activity was more abundant after exponential growth ceased. Both esterases were present in the supernatant fraction of lysed spheroplasts and in a disrupted spore preparation. Of four pleiotropic asporogenous mutants tested, three exhibited decreased esterase B activity. Esterases A and B were partially purified by differential precipitation and co-chromatographed on diethylaminoethyl (DEAE)-cellulose (pH 7.5) and DEAE-Sephadex (pH 8.5). By employing gel filtration chromatography, the two esterases were separated, and molecular weights of 160,000 and 51,000 were estimated for esterases A and B, respectively. Esterase A was further purified to electrophoretic homogeneity by differential heating and preparative starch block electrophoresis. Sodium dodecyl sulfate-acrylamide gel electrophoresis of purified esterase A yielded a single protein band with a molecular weight of 31,000. The pI values of esterases A and B were determined to be 6.4 and 5.4, respectively. PMID- 4197270 TI - Measurement of the cyanophycin granule polypeptide contained in the blue-green alga Anabaena cylindrica. AB - An assay was developed to determine the amount of cyanophycin granules in blue green algae. The amount of this polypeptide in cells of Anabaena cylindrica was measured as a function of culture age and was compared with changes in other proteinaceous cellular components. The data presented support the notion that the cyanophycin granule is a cellular nitrogen reserve. PMID- 4197271 TI - Mapping of asporogenous mutations of Bacillus subtilis: a minimum estimate of the number of sporeulation operons. AB - Sporulation-specific mutations in Bacillus subtilis have been mapped by transduction and transformation. The mutations caused blocks at stages 0, II, III, and IV of sporulation; more than one phenotype was found for each of these stages. On the basis of the criteria used to define a sporulation operon, a minimum estimate could be made of the number of operons activated during sporulation. Nine operons were identified for stage 0, eight for stage II, five for stage III, and six for stage IV. It is probable that several of these 28 operons are activated in groups so that the number of steps in the dependent sequence of sporulation events should turn out to be less than the number of operons. PMID- 4197272 TI - Use of constructed double mutants for determining the temporal order of expression of sporulation genes in Bacillus subtilis. AB - Double mutants containing two Spo mutations concerned with different stages of sporulation were constructed. In these, the phenotype that is exhibited is that of the earlier sporulation block. The same procedure was applied to sporulation mutants damaged in the same stage of development. The results provide a basis for placing in a temporal order different mutations concerned in stage II and stage IV of spore development. In general, the order indicated by the phenotypes of the double mutants is in agreement with the order derived on biochemical grounds. Double oligosporogenous mutants have also been constructed. Their sporulation incidence is roughly equal to the product of the incidences of the parent strains, idicating that separate factors are involved in overcoming each oligosporogenous block. The number of dependent sequential steps in sporulation is estimated as not less than about 12. PMID- 4197273 TI - Surface structure of gliding bacteria after freeze-etching. AB - Ultrastructural studies of gliding bacteria demonstrate 10- to 11-nm beads on the inner surface of the outer bilayer of Cytophaga columnaris. These were not found in Myxococcus xanthus. On treatment with glutaraldehyde and ethanol, the beads appear in linear arrays. PMID- 4197275 TI - Prophylactic therapy of angina pectoris with organic nitrates: relationship of drug efficacy and clinical experimental design. PMID- 4197276 TI - Pathogenesis of Marek's disease: early distribution of virus and viral antigens in infected chickens. PMID- 4197274 TI - Extractable lipids of gram-negative marine bacteria: phospholipid composition. AB - Phospholipid compositions of 20 strains of marine and estuarine bacteria were determined. Results showed that phospholipids of marine bacteria differed very little from those of nonmarine organisms with phosphatidylethanolamine, phosphatidylglycerol, and diphosphatidylglycerol being the predominant phospholipids in all strains examined. Lyso-phosphatidylethanolamine occurred in significant quantities among a number of the marine bacteria, and two of the isolates contained significant quantities of poly-beta-hydroxybutyrate. Effects of age and growth temperature on the phospholipid composition were also investigated. It is suggested that phylogenetic relationships among bacteria may be correlated with phospholipid composition. PMID- 4197277 TI - Urinary metabolic profiles for choosing test animals for chronic toxicity studies: application to naproxen. PMID- 4197278 TI - Effects of d-amphetamine on schedule-controlled key pressing and drinking in the chimpanzee. PMID- 4197279 TI - Pharmacology of cyanate. I. General effects on experimental animals. PMID- 4197280 TI - [Thyroid gland and pregnancy]. PMID- 4197281 TI - The long-stay hospital--a modern concept. PMID- 4197282 TI - [Experiences with glibenclamide therapy of diabetes]. PMID- 4197283 TI - [The role of immunological factors in the pathogenesis of bronchial asthma]. PMID- 4197284 TI - On the application of knowledge to the patient with genetic disease. PMID- 4197285 TI - Metaplastic bone formation in the lung. PMID- 4197286 TI - [Macrodactyly and fibrolipoma of the median nerve (phacomatosis)]. PMID- 4197287 TI - Encephalopathy and fatty degeneration of viscera: Reye's syndrome. PMID- 4197288 TI - Detecting Marek's disease herpesvirus: evaluation of biological systems. PMID- 4197289 TI - Microimmunodiffusion test for hemorrhagic enteritis of turkeys. PMID- 4197290 TI - Cancer and the evolution of species: a ransom. PMID- 4197291 TI - The skin in disseminated intravascular coagulation. Prospective analysis of thirty-six cases. PMID- 4197292 TI - Subnuclear redistribution of DNA species in confluent and growing mammalian cells. PMID- 4197293 TI - Determination of the binding of thyroxine to plasma proteins by competitive protein-binding analysis. PMID- 4197294 TI - Polyacrylamide gel electrophoresis of human sera collected at different times after meals. PMID- 4197296 TI - Immunochemical study of relationships between erythrocyte glucose-6-phosphate dehydrogenase (G6PD, E.C. 1.1.1.49) of various mammalian species. PMID- 4197295 TI - Evidence for a 5'-nucleotidase in human leukemic leukocytes. PMID- 4197297 TI - Incorporation of 32 P during early amphibian embryogenesis. PMID- 4197298 TI - The biochemical properties of esterases in Cepaea (Mollusca: Helicidae). PMID- 4197299 TI - Experimental induction heating hypophysectomy. PMID- 4197300 TI - Properties of glycogen synthetase in erythrocytes. PMID- 4197301 TI - [Directives for balanced parenteral nutrition]. PMID- 4197302 TI - Enzymic changes in taste buds of monkey following transection of glossopharyngeal nerve. PMID- 4197303 TI - Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet. PMID- 4197304 TI - Protein A from Staphylococcus aureus. XIV. The effect of nitration of protein A with tetranitromethane and subsequent reduction. PMID- 4197305 TI - A new preparative method for isolation of human C3 with affinity chromatography. PMID- 4197306 TI - Immunochemical study of group A streptococcus peptidoglycan solubilized by 8M urea. PMID- 4197307 TI - Histochemical evidence for phosphorylase, branching enzyme and glycogen synthetase activities in rat brain. PMID- 4197308 TI - Hyperlipidemia and diabetes mellitus: can electron microscopy help in the diagnosis. PMID- 4197309 TI - Regulation of growth hormone and prolactin secretion in patients with acromegaly and-or excessive prolactin secretion. PMID- 4197310 TI - Evidence for possible precursors in the synthesis of growth hormone by rat and human fetal anterior pituitary in vitro. PMID- 4197311 TI - Inherited variations in thyroxine transport. PMID- 4197312 TI - Death and dying. A critical review of the literature. PMID- 4197313 TI - Clinical grade, egional cerebral blood flow and angiographical spasm in the monkey after subarachnoid and subdural hemorrhage. PMID- 4197315 TI - [Disinfection of medical machines using peracetic acid-aerosol]. PMID- 4197314 TI - Analyses of proteinases in washing powders. PMID- 4197316 TI - The retro-articular vertebral artery ring of the atlas and its significance. PMID- 4197317 TI - [Variability of innervation of the large vessels]. PMID- 4197318 TI - Diverticulum or aneurysm of left ventricle. PMID- 4197319 TI - Basis of static and dynamic electrocardiographic variations in Wolff-Parkinson White syndrome. Anatomic and electrophysiologic observations in right and left ventricular preexcitation. PMID- 4197320 TI - The acylation of glycerol 3 -phosphate in different rat organs and in the liver of different species (including man). PMID- 4197321 TI - Dysplasia epiphysialis hemimelica with confirmation by knee arthrography. PMID- 4197322 TI - Visual discrimination performance in the monkey: the activity of single cells in infero-termporal cortex. PMID- 4197323 TI - Certain ventromedial hypothalamic afferents. PMID- 4197324 TI - Septic shock (endotoxic shock). PMID- 4197326 TI - [ABO and RH groups in children with alveolar process and palatal clefts]. PMID- 4197325 TI - Gonorrhea: changing concepts in diagnosis and management. PMID- 4197327 TI - A proposed role for ascorbate in the transport of amino acids and ions in the cornea. PMID- 4197328 TI - The toad's (Bufo marinus) lens and urinary bladder as mural membranes: a comparison. PMID- 4197329 TI - [Short-term pilot study of the feasibility of multifactor reduction of coronary risk]. PMID- 4197330 TI - 6-Azauracil induced phenocopies of rudimentary wing mutants and their suppression by a suppressor mutant of rudimentary in Drosophila melanogaster. PMID- 4197331 TI - Somatic resistance to X-ray treatment in Drosophila melanogaster populations with different irradiation backgrounds. PMID- 4197332 TI - In vitro IgM antibody synthesis by human tonsil-derived lymphocytes. PMID- 4197333 TI - Complement: optimal reaction conditions for guinea pig C4. PMID- 4197334 TI - Complement: a reversible temperature-dependent alteration in the reactivity of EAC1 with C4. PMID- 4197335 TI - Lysosomal enzyme release from human leukocytes: mediation by the alternate pathway of complement activation. PMID- 4197336 TI - Antigen-T lymphocyte interactions: inhibition by cytochalasin B. PMID- 4197337 TI - Regulation of ribonucleic acid synthesis in Escherichia coli B-r: an analysis of a shift-up. II. Fraction of RNA polymerase engaged in the synthesis of stable RNA at different steady-state growth rates. PMID- 4197338 TI - Occurrence of heat-dissociable ribosomal RNA in insects: the presence of three polynucleotide chains in 26 S RNA from cultured Aedes aegypti cells. PMID- 4197339 TI - Response to noise of auditory nerve fibers in the squirrel monkey. PMID- 4197340 TI - Role of abducens neurons in vestibuloocular reflex. PMID- 4197341 TI - Location of cells of origin of spinothalamic tract in lumbar enlargement of the monkey. PMID- 4197342 TI - The histopathology of vesical diverticula. PMID- 4197343 TI - Neoplasm in vesical diverticula: report of 4 patients, including a 21-year-old. PMID- 4197344 TI - [Study of the antigenic make-up of some Klebsiella rhinoscleromatis fractions by the agar diffusion method]. PMID- 4197345 TI - [Diagnostic methods for the detection of amino acid metabolism disorders]. PMID- 4197346 TI - Isolation, purification and structure of Aleutian disease virus by immunological techniques. PMID- 4197347 TI - Does the rDNA in the Y chromosome of Drosophila melanogaster magnify? PMID- 4197348 TI - Neural control of social behavior: prefrontal and anterior temporal cortex. PMID- 4197349 TI - Functional dissociation between the inferior and arcuate segments of dorsolateral prefrontal cortex in the monkey. PMID- 4197350 TI - Cross-modal transfer between vision and touch of go, no-go discrimination learning in the monkey. PMID- 4197351 TI - [Immunization against L-asparaginase. Demonstration and characteristics of antibodies. Clinical value]. PMID- 4197352 TI - [Septicemia with Listeria monocytogenes following abortion induced after 2 and one-half months]. PMID- 4197353 TI - Chlorthalidone in the treatment of angina pectoris. PMID- 4197354 TI - [Hereditary myatrophical ataxia--syndrome or diagnosis? Critical remarks on the nosology of hereditary degenerative diseases from the viewpoint of medical genetics]. PMID- 4197355 TI - [Hypothalamic regulation of anterior pituitary secretion]. PMID- 4197356 TI - [Geriatrics and long term medicine]. PMID- 4197357 TI - Effect of trisodium nitrilotriacetate (Na 3 NTA) on the metabolism of selected metal ions. PMID- 4197358 TI - Intestinal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (disodium etidronate) using a deconvolution technique. PMID- 4197360 TI - Sensitization to epinephrine-induced ventricular fibrillation produced by probucol in dogs. PMID- 4197359 TI - Toxicity of (4,4'-(isopropylidenedithio)bis(2,6-di-t-butylphenol)), probucol, in mice, rats, dogs and monkeys: demonstration of a species-specific phenomenon. PMID- 4197361 TI - [The production of antibodies against the "Australia" antigen in rabbits and guinea pigs]. PMID- 4197362 TI - [Stomach diverticula]. PMID- 4197363 TI - [Neurofibromatosis of the cervico-occipital region]. PMID- 4197364 TI - [Effect of the antibiotics resistomycin and resistoflavin on growth, nucleic acid and protein synthesis in Bacillus subtilis]. PMID- 4197365 TI - Effect of aflatoxins on microorganisms. PMID- 4197366 TI - [Determination of serum iron and total iron-binding capacity in blood donors]. PMID- 4197367 TI - [Plasma insulin and glucose levels in diabetics treated with glibenclamide and chlorporpamide]. PMID- 4197368 TI - Hemodynamic changes during complete heart block in the unanesthetized monkey. PMID- 4197369 TI - Detection of medullary thyroid cancer by calcitonin assay in families. PMID- 4197370 TI - Rapid correction of hyponatremia in the syndrome of inappropriate secretion of antidiuretic hormone. An alternative treatment to hypertonic saline. PMID- 4197371 TI - Asthma caused by nickel sensitivity. PMID- 4197372 TI - The early phase of acute myocardial infarction: pharmacologic aspects of therapy. PMID- 4197373 TI - National health plans: some economic and financial aspects. PMID- 4197374 TI - Cromolyn prophylaxis for chronic asthma. PMID- 4197375 TI - Alcoholism and ketoacidosis. PMID- 4197376 TI - Electron microscopic studies on transplantable melanotic and amelanotic melanomas in hamsters. PMID- 4197377 TI - Effects of bacterial products on a Paramecium esterase. PMID- 4197378 TI - Studies of a homologous gene-enzyme system, esterase C, in Drosophila melanogaster and Drosophila simulans. PMID- 4197379 TI - Is hemoglobin A 2 important? PMID- 4197380 TI - The relationship of substrate, growth rate, and maintenance coefficient to single cell protein production. PMID- 4197381 TI - Polysomes of cultured normal and leukaemic lymphocytes: response to phytohaemagglutinin. PMID- 4197382 TI - A method for the measurement of platelet adhesiveness by use of dialysis membranes in a test-cell. PMID- 4197383 TI - [Ulcer of the fornix perforated into the spleen, simulating a gastric diverticulum]. PMID- 4197384 TI - The effect of anticonvulsant therapy upon the absorption of folates. PMID- 4197385 TI - Body potassium and fat-free mass. PMID- 4197386 TI - Effects of long-term feeding of polychlorinated biphenyls (PCB, Clophen A 60) on the length of the oestrous cycle and on the frequency of implanted ova in the mouse. PMID- 4197387 TI - Multiple myeloma proteins: evaluation of laboratory methods as aids for diagnosis. PMID- 4197388 TI - Transmissible mink encephalopathy: studies on the peripheral lymphocyte. AB - Circulating lymphocytes from mink with transmissible mink encephalopathy were studied for the presence of virus particles and for infectivity. Electron microscope examination of phytohemagglutinin-stimulated lymphocyte cultures revealed no evidence of virus-like particles. Circulating lymphocytes were also found to be noninfectious when the transmissible agent could be demonstrated in intact lymphoid organs in infected mink. A lymphopenia was detected in affected mink during the late clinical stage of disease, but this was most likely a secondary effect due to a terminal stress factor. PMID- 4197389 TI - Studies on the virulence of Neisseria gonorrhoeae. I. Relation of colonial morphology and resistance to phagocytosis by polymorphonuclear leukocytes. AB - Colonial varieties of Neisseria gonorrhoeae that are associated with virulence, types 1 and 2, were more resistant to phagocytosis by rabbit exudative polymorphonuclear leukocytes than colonial types of lesser virulence, types 3 and 4. Type 1 bacteria were resistant and type 4 gonococci were susceptible to phagocytosis by human polymorphonuclear leukocytes. Recent local type 1 isolates were similar in resistance to type 1 organisms of a standard laboratory strain (F62). Living and Formalin-treated, heat-killed, type 1 gonococci were equally resistant to phagocytosis. The antiphagocytic property of virulent colonial types was independent of leukotoxic action. Phagocytosis of both type 1 and type 4 gonococci by rabbit and human leukocytes was bactericidal. Rabbit leukocytes were superior to human leukocytes in killing gonococci. The results suggest that N. gonorrhoeae has virulence properties similar to those of extracellular bacterial pathogens, i.e., virulence is associated with antiphagocytic properties. PMID- 4197390 TI - Mumps class-specific immunoglobulins in radioimmunoassay and conventional serology. AB - In assessing the host cell range of bovine parvoviruses, these viruses were found to replicate optimally in actively dividing bovine fetal lung and spleen cells. Other primary bovine fetal cells supported growth to a lesser extent, but bovine line cells and line cells of other animal species tested did not. Minimal infectivity remained after passage of bovine parvovirus in cells from chicken embryos and guinea pig fetuses. During bovine parvovirus replication in bovine fetal lung and spleen cells, production kinetics of infectious virus and hemagglutinins were determined. An eclipse period of 16 h occurred, and viral release from cells was not detected until 30 h after inoculation of bovine fetal lung cells and 36 h after inoculation of bovine fetal spleen cells. Cell associated virus titers were always higher than extracellular virus titers. Hemagglutinins were detected in parallel to infectious virus. PMID- 4197391 TI - Interaction of virulent and avirulent Listeria monocytogenes with cultured mouse peritoneal macrophages. AB - The interaction between smooth and rough Listeria monocytogenes and mouse peritoneal macrophages in culture was investigated. Initially, antibiotics were deleted from the culture medium, and no attempt other than the removal of unphagocytized bacteria by extensive washings was made to control extracellular growth. Under these conditions the monolayers were rapidly destroyed within an 8 h period, and this was associated with increases in the intracellular population of both strains. Extracellular viability counts revealed that washings failed to reduce the bacteria in the medium to less than 10% of the original inoculum. Continuous phagocytosis of Listeria which grew logarithmically in the maintenance media appears to account for the observed changes in the number of intracellular bacteria. The data also indicate that it is primarily the free bacteria in the culture medium which are responsible for the cytotoxic effects. In other experiments streptomycin-penicillin solutions were added to the maintenance media after an initial period of phagocytosis. In the presence of antibiotics, the total number of macrophages per field remained relatively constant, and no morphological alterations in the leukocyte cultures were observable. Extensive intracellular multiplication of either strain was not evident in fixed and stained cover slips. Viable intracellular counts reveal that after 24 h there is almost total killing of the rough variant, whereas the smooth strain tended towards complete survival. PMID- 4197392 TI - Effects of antithymocyte and antimacrophage sera on the survival of mice infected with Listeria monocytogenes. AB - Antisera prepared in rabbits against purified mouse thymocytes (antithymocyte serum; ATS) and peritoneal macrophages (antimacrophage serum; AMS) were injected intraperitoneally into Balb/c mice infected with the bacterium Listeria monocytogenes. When administered near the initiation of infection, the ATS significantly decreased the survival time of the animals and increased the mortality rate. When ATS was administered 6 days after a sublethal dose of L. monocytogenes had been inoculated, an overt disease did not evolve. ATS that significantly potentiated primary listeriosis also had high cytotoxicity titers for thymocytes and lymphoid cells from the peritoneal cavity. Although cytotoxic activity against peritoneal macrophages could be demonstrated in lower dilutions of the ATS, this activity did not appear to correlate with the effects of the sera on listeriosis. The injection of AMS did not enhance the infectious process. In some trials more deaths occurred among mice receiving normal rabbit serum than those receiving AMS. All of the AMS had cytotoxic titers against peritoneal macrophages, and the sera were usually inactive against thymocytes and peritoneal lymphoid cells. Listeria was isolated from fatally infected mice with nearly equal success in all of the serum-treated groups, and the serum treatments did not appear to alter the pattern of gross lesions. The afferent limb of the immune response was markedly affected by the presence of antibodies to lymphocytes. However, antibodies reacting with macrophages did not demonstrably enhance the Listeria process, which depends upon cellular immunity as the principal means of acquired host defense. PMID- 4197393 TI - Nonhemolytic group B streptococci of human, bovine, and ichthyic origin. AB - The biochemical and serological characteristics of nonhemolytic group B streptococci of human, bovine, and ichthyic origin were described. PMID- 4197394 TI - Salivary, nasal wash, and sputum IgA concentrations in atopic and nonatopic individuals. PMID- 4197395 TI - Stimulation of DNA synthesis and 2-deoxy-D-glucose transport in chick embryo cultures by excessive metal concentrations and by a carcinogenic hydrocarbon. PMID- 4197396 TI - Ossifying fibroma of mandible with a case report. PMID- 4197397 TI - [Basic principles of lid reconstruction]. PMID- 4197398 TI - [Internuclear ophthalmoplegia in Morbus Fabry-Anderson]. PMID- 4197399 TI - [Formation of extracellular RNAses by microorganisms on a synthetic medium]. PMID- 4197400 TI - [Streptococcus faecalis tyrosine decarboxylase]. PMID- 4197401 TI - [Toxic properties of the metabolites of some saprophytic bacteria]. PMID- 4197402 TI - Committee on maternal welfare. PMID- 4197403 TI - Kidney transplantation in Fabry's disease. PMID- 4197404 TI - [Lumbal and sacral root-pocket diverticula as the cause of sciatica-like pain]. PMID- 4197405 TI - Cerebral cortical control of movement. PMID- 4197406 TI - Cardiovascular observations in the Macaca nemestrina monkey in Biosatellite 3. PMID- 4197407 TI - Circadian rhythms and sleep-wake activity in the Biosatellite monkey. PMID- 4197408 TI - Wake and sleep cycles in the Biosatellite 3 primate in earth orbital flight. PMID- 4197409 TI - Electrolyte and metabolic problems of weightlessness. PMID- 4197410 TI - The prospect of life on Jupiter. PMID- 4197411 TI - [Effect of blood-circulation-active drugs on dp-dt max and V CEmax of the left ventricle]. PMID- 4197412 TI - [Lesions of the auditory nerve in neurofibromatosis]. PMID- 4197413 TI - Isolation and characterization of a virus infecting a blue-green alga of the genus Synechococcus. PMID- 4197414 TI - Aspects of the developmental morphology of California encephalitis virus in cultured vertebrae and arthropod cells and in mouse brain. PMID- 4197415 TI - Accommodation of the eye during sleep and anesthesia. PMID- 4197416 TI - The oscillatory waves of the primate electroretinogram. PMID- 4197417 TI - Retinal receptive fields: correlations between psychophysics and electrophysiology. PMID- 4197418 TI - Servo-controlled moving stimulus generator for single unit studies in vision. PMID- 4197419 TI - Progress in oral therapy of diabetes mellitus with sulphonylureas of the second generation. PMID- 4197420 TI - Field trial of the efficacy of a previously proposed regimen using minocycline and rifampin sequentially for the elimination of meningococci from healthy carriers. PMID- 4197421 TI - Massive hemorrhage associated with circulating antibodies to factor V. PMID- 4197423 TI - Induced hypothermia: its place in modern hospital practice. PMID- 4197424 TI - [Biomechanical analysis of disordered ossification in coxa vara and its normalisation by corrective osteotomies]. PMID- 4197422 TI - Experimental calcification of the myocardium. Ultrastructural and histochemical investigations. AB - Focal areas of calcification are frequent in rat myocardium 30 and 60 days after administration of dihydrotachysterol. These areas are PAS-positive, stain deeply with alcian blue and show high affinity for colloidal iron. Calcification is almost completely confined to intracellular structures. Small clusters of needle shaped crystals are first found in apparently undamaged mitochondria in undamaged myocardial cells. When all the mitochondria are calcified, the cell degenerates, and inorganic crystals are laid down in relationship with its myofilaments. In other myocardial cells, clusters of amorphous or finely granular inorganic substance are found in both mitochondria and myofibrils. Both structures show signs of advanced degeneration. Inorganic substance has only occasionally been found within the structures of the sarcoplasmic reticulum. These structures do not seem to be involved in myocardial calcification under the present experimental conditions. Calcification of myocardial cells gives rise to a cellular reaction. Many macrophagic cells surround the calcified areas, which are rapidly reabsorbed. The present results show that myocardial mitochondria are actively engaged in controlling the intracellular concentration and movement of calcium ions. Their role in the myocardial contraction-relaxation cycle and the possible mechanism of myocardial calcification are discussed. PMID- 4197425 TI - Euglycaemic diabetic ketoacidosis. AB - Of a series of 211 episodes of diabetic metabolic decompensation 37 had severe euglycaemic ketoacidosis (a blood sugar level of less than 300 mg/100 ml and a plasma bicarbonate of 10 mEq/1. or less). All were young insulin-dependent diabetics, only one being previously undiagnosed. Vomiting was a common factor, and in all carbohydrate reduction occurred with continued or increased daily insulin dose. Treatment comprised fluid and electrolyte replacement and large doses of insulin covered by adequate carbohydrate, many receiving 10% dextrose. Alkali was either withheld or given sparingly and the therapy was monitored by serial estimations of plasma bicarbonate. All the patients survived. PMID- 4197426 TI - Formylation of folate as step in physiological folate absorption. AB - Oral administration of folate analogues to rats is followed by a rise in plasma folate detectable only by micro-biological assay with Lactobacillus casei, suggesting methylation of folate during absorption. When using the everted rat gut technique with folate (PteGlu), dihydrofolate (H(2)PteGlu), or tetrahydrofolate (H(4)PteGlu) on the mucosal surface formyl folate (10-CHO PteGlu, 10-CHO-H(4)PteGlu, 5-CHO-H(4)PteGlu) and methylfolate (5-CH(3) H(4)PteGlu) are recovered from the serosal fluid. This indicates that absorption of PteGlu is followed by formylation and that the formyl group is further reduced to methyl, 5-CH(3)-H(4)PteGlu passing on to portal blood. PMID- 4197427 TI - Representation of information about skin temperature in the discharge of single cortical neurons. PMID- 4197428 TI - , Mishkin M:Comparison of superior temporal and inferior prefrontal lesions on auditory and non-auditory tasks in rhesus monkeys. PMID- 4197429 TI - Cutaneous receptive fields of primate cold fibers. PMID- 4197430 TI - Studies on isolated keratin fractions from mammalian epidermis. II. Immunological and immuno-electrophoretic comparison of the fractions. PMID- 4197431 TI - [Maximum dosage for oral antidiabetics]. PMID- 4197432 TI - Position sense after combined spinal tractotomies and cerebellectomies in macaques. PMID- 4197433 TI - Interactions of sensory and nonspecific thalamic inputs to cortical polysensory units in the squirrel monkey. PMID- 4197434 TI - Specific hapten binding activity in normal sera. PMID- 4197435 TI - B-lymphocyte mediated cytolysis: a complement independent phenomenon. PMID- 4197436 TI - Incidence of Australia antigen in voluntary and professional blood donors and also in cases of viral hepatitis. PMID- 4197437 TI - Cost accounting of health centre expenditures. PMID- 4197438 TI - Airway problems in the intensive care unit. PMID- 4197439 TI - Lysis of antibody-treated human erythrocytes by human leukocytes and macrophages in tissue culture. PMID- 4197440 TI - Micromethod for immunochemical quantitation of dextran and studies on role of antigen size in single radial immunodiffusion. PMID- 4197441 TI - Defined immunofluorescence studies of cytoplasmic antibodies. PMID- 4197442 TI - Ambient light, white noise, and monkey vocalization as sources of interference in visual short-term memory of monkeys. PMID- 4197443 TI - Spectrofluorometric determination of substituted dihydroisoquinolines and tertiary tetrahydroisoquinolines as their isoquinolinium derivatives. PMID- 4197444 TI - Comparative study of myocardial lesions in hemorrhagic shock. PMID- 4197446 TI - [Physiological characteristics of fluorescent saprophytic bacteria of the genus Pseudomonas capable of liquefying gelatin]. PMID- 4197445 TI - Effects of pressure gradient changes on the morphology of arachnoid villi and granulations of the monkey. PMID- 4197447 TI - [Growth characteristics of various Aspergillus species on petroleum hydrocarbon media]. PMID- 4197448 TI - [Species composition and antibiotic properties of the actinomycetes of soddy podzolic soils in the rhizosphere of pine stands]. PMID- 4197450 TI - Capacitor electrode stimulates nerve or muscle without oxidation-reduction reactions. AB - Porous tantalum disks, available as "slugs" from the capacitor industry, have large available surface area and a thin insulating coating of tantalum pentoxide. When implanted, they fill with extracellular fluid and operate as capacitor stimulating electrodes having high capacitance per unit volume. Capable of stimulating excitable tissute without generating electrochemical by-products, these electrodes should provide a safer interface between neural prosthetic devices and human tissue. PMID- 4197449 TI - [Pattern of venous phase in vertebral angiography in acoustic neurinomas]. PMID- 4197451 TI - [Determination of sevin and 1-naphthol in cadaveric material by thin-layer chromatography]. PMID- 4197452 TI - Renal blood flow during endotoxin shock in the subhuman primate. PMID- 4197453 TI - Elemental diet in the treatment of fistulas of the alimentary tract. PMID- 4197455 TI - [Specificity and activity of P.P.D. tuberculin from human and bovine type strains]. PMID- 4197454 TI - The ocular manifestations of congenital rubella. PMID- 4197456 TI - [Culturing the vaccine strain of swine plague virus in a cell suspension]. PMID- 4197457 TI - [Effectiveness of inagglutinogenic vaccine against brucellosis]. PMID- 4197458 TI - [Effect of metaphos on cattle]. PMID- 4197459 TI - [Chemotherapy of lung cancer]. PMID- 4197460 TI - Safe use of pesticides. PMID- 4197461 TI - [Immune-cytological studies on the distribution pattern of Ig determinants in myeloma patients. Thoughts on a class specific restriction to B-lymphocytes]. PMID- 4197462 TI - Status of monosodium glutamate revisited. PMID- 4197463 TI - Status of monosodium glutamate revisited. PMID- 4197464 TI - Folate content of diets in pregnancy: comparison of diets collected at home and diets prepared from dietary records. PMID- 4197465 TI - The neglect of nutrition and its perils. PMID- 4197466 TI - Nutrition: its relationship to children's physical, mental, and emotional development. PMID- 4197467 TI - Graded contractions in muscle strips and single cells from Bufo marinus stomach. PMID- 4197468 TI - Variation in endotoxin-induced kinin production and effect between the rabbit and rhesus monkey. PMID- 4197469 TI - Toxicology of radionuclides. PMID- 4197470 TI - Neuropharmacology of the affective disorders. PMID- 4197471 TI - Heterotopic ossification in abdominal operation scars. PMID- 4197472 TI - Spondylo-metaphyseal dysplasia. PMID- 4197473 TI - Dyggve disease. PMID- 4197474 TI - [HBAg (HAA-Australia antigen) purification and preparation of specific antiserum from guinea pigs]. PMID- 4197475 TI - The effect of D-L-erythro- - -dihydroxybutyraldehyde (DIBA) on the spores of Bacillus cereus: germination, stimulation and outgrowth inhibition. PMID- 4197476 TI - Scleromalacia perforans associated with Crohn's disease. Treated with sodium versenate (EDTA). PMID- 4197477 TI - Increased dosage of disodium cromoglycate. PMID- 4197478 TI - [Specific fluorescence of R and G bands in human chromosomes]. PMID- 4197479 TI - [Nonreversible degradation rate of L-leucine in vivo. Effect of somatotropic hormone]. PMID- 4197480 TI - [Hyperphagia induced in geese by intraventricular injections of 6 hydroxydopamine]. PMID- 4197481 TI - [Active transport of sodium through seminal vesicles in the anuran Discoglossus pictus]. PMID- 4197482 TI - [Polarized exocytosis of lysosomal residues of prolactin-producing cells in adenohypophysis of postlactating rats]. PMID- 4197483 TI - [Estrogen biosynthesis in ovary of hypophysectomized chick embryos: quantitative aspect]. PMID- 4197484 TI - [Changes in amplitude spectrum of electroencephalogram induced by mental activity and detected by ASA minicomputer]. PMID- 4197485 TI - [Attempt to interpret kinetic data from Golgi fraction of chicken germinal epithelium during organotypic culture]. PMID- 4197486 TI - [Effect of toxic products on net building by Hydropsyche larva (Insecta, Trichoptera)]. PMID- 4197487 TI - [Formation of chimeric blastocysts by fusion of rat and mice embryos at stage 8]. PMID- 4197488 TI - [Role of mesectoderm in the genesis of aortic arches of the bird embryo]. PMID- 4197489 TI - [Cytochemical distinction between catalase and peroxidase]. PMID- 4197491 TI - [Spontaneously diffusible nucleic acids in isolated nuclei of rat hepatocytes. New biochemical and morphological data]. PMID- 4197490 TI - [Cholinergic system enzymes in the F 1 hybrids of mice differing in their capacity for conditioning]. PMID- 4197492 TI - [Phospholipid conformation and modulation of template effect of chromatin (DNA polymerase activity)]. PMID- 4197493 TI - [Glycopeptides obtained by proteolysis of a basic glycoprotein in human parotid saliva]. PMID- 4197494 TI - [Size of dissociation products of scorpion Androctonus australis (L.) hemocyanin]. PMID- 4197495 TI - [Conformational analysis of the hypothalamus hormone TRF with Raman spectroscopy]. PMID- 4197496 TI - [In vivo and in vitro study of tolbutamide, a hypoglycemic sulfamide: effects on pancreatic glucagon secretion]. PMID- 4197497 TI - [Increase in the immunostimulation properties of inactivated Brucella abortus B 19 by simultaneous use of a specific immune serum]. PMID- 4197498 TI - [New technic for determination of lymphocyte populations in cultured mice spleen. Results after phytohemagglutinin activation]. PMID- 4197499 TI - [Cytological and cytochemical study of mouse Ehrlich tumor cells cultured in vitro]. PMID- 4197500 TI - [Hypothalamic hormones and regulation of endocrine functions]. PMID- 4197501 TI - [Immunoelectrophoresis in dermatological practice. (I. Paraproteinemias)]. PMID- 4197502 TI - [Delayed-action penicillins in infants]. PMID- 4197503 TI - Efficacy of glibenclamide in maturity-onset diabetics as maintenance therapy. PMID- 4197504 TI - Effect of oxytocin and epinephrine on the adenylate cyclase activity of myometrium from pregnant Rhesus monkeys. PMID- 4197505 TI - Fixed-interval schedule of cocaine reinforcement: effect of dose and infusion duration. AB - Rhesus monkeys were trained on a fixed-interval 9-min limited-hold 3-min schedule of intravenous cocaine reinforcement. A 15-min timeout followed each reinforcement or limited-hold expiration. An identical schedule of food reinforcement was interspersed in the session to assess rate-modifying effects of the drug infusions not specific to drug reinforcement. In one experiment, response rate for cocaine reinforcement was shown to be a positive function of reinforcement magnitude for a dose range from 0 to 800 ug/kg/inj. At these doses, there was little effect on food reinforced responding except at the highest dose, where responding decreased. Results of the second experiment indicated that increasing the duration of the cocaine infusion produced a change in response rate similar to decreasing unit dose. The response rate change for a given increase in infustion duration was less at a unit dose of 400 ug/kg than at 200 ug/kg. PMID- 4197506 TI - Long-term prereward suppression in monkeys unaccompanied by cardiovascular conditioning. AB - In Experiment I, a 3-min tone that preceded a free pellet of food suppressed variable-interval performances maintained by the same type of pellets, but failed to elicit conditioned changes in the heart rates and blood pressures of two rhesus monkeys. Initially severe, the prereward suppression became temporally discriminated to progressively later portions of the tone, and was maintained at an attenuated level for over four months. The suppression was apparently not caused by interfering autonomic respondents, nor was it superstitiously conditioned, since 21 of the initial 25 tone-food pairings took place outside of baseline sessions. In Experiment II, a 1-min light, paired with four free pellets of food, suppressed the variable-interval responding of a second pair of similarly trained monkeys. An interresponse-time analysis showed that in one subject, mild prereward suppression of responding developed through two stages. On early trials, response rate slowed by 10% throughout the prefood interval. On later trials, the animal suppressed by pausing for a like portion of the interval, most often near the end, but otherwise responded normally during the prefood signal. PMID- 4197507 TI - The chronic toxicity of retrorsine, a pyrrolizidine alkaloid, in vervet monkeys. PMID- 4197508 TI - [Evaluation of fetal maturity and fetal risk]. PMID- 4197509 TI - [Listeriosis following renal transplantation]. PMID- 4197510 TI - [Biology of Listeria infections. Effect of immunodepression]. PMID- 4197511 TI - [Restoration of pulpless teeth (case reports)]. PMID- 4197512 TI - [Composite resins as restorative materials]. PMID- 4197513 TI - [Diabetes mellitus and oral surgery]. PMID- 4197514 TI - [Ankle injuries caused by bicycle spikes in childhood]. PMID- 4197515 TI - [Immune reactive insulin studies]. PMID- 4197516 TI - Use of thyrotrophin releasing hormone test in pituitary disease. PMID- 4197517 TI - Effect of pyrithioxine (Encephabol) on growth and exploratory behaviour of rats malnourished in early life. PMID- 4197518 TI - The nature of performance deficity under secobarbital and chlorpromazine in the monkey. A behavioral and EEG study. PMID- 4197519 TI - [Behavior of the immunoglobulins and other plasma proteins in malignant lymphomas studies by immunological methods]. PMID- 4197520 TI - Studies on gold therapy with 198 gold sodium thiomalate. PMID- 4197521 TI - [Aerosols of chemical agents against the chicken tick, Dermanyssus fallinae]. PMID- 4197522 TI - [Coccidiostatic effectiveness of 3,5-dinitrobenzamide in the storage of combined fodder]. PMID- 4197523 TI - [Epithelial villi and epithelial net works. Pathological histology of the breast. VI]. PMID- 4197524 TI - Prevention by cycloheximide of neutral red-induced formation of autophagic vacuoles and krinom granules in mouse pancreatic acinar cells. PMID- 4197525 TI - Morphological studies of cultured swine aorta media explants. PMID- 4197526 TI - Effects of anti-thymocyte serum on the phagocytic acivity of hepatic and splenic macrophages. PMID- 4197527 TI - [Electron microscopy findings on parathyroid adenomas of varying endocrine activity]. PMID- 4197528 TI - Intranuclear mitochondriae in Hodgkin's disease. PMID- 4197529 TI - The centrineurogenic etiology of the acute respiratory distress syndromes. Universal, species--independent phenomenon. PMID- 4197530 TI - Tricuspid valvulectomy without prosthetic replacement. PMID- 4197531 TI - Phosphorylase activity in the arterial wall. PMID- 4197532 TI - Economic pressures--and quality nursing. PMID- 4197533 TI - Antibacterial effect of an interferon-inducing polycarboxylate. Mechanism of action. PMID- 4197534 TI - Detection of homocytotropic human antibodies by passive sensitization "in vitro" of monkey lung tissue. I. Optimum conditions fo use of lung tissue. PMID- 4197535 TI - Fixation of albumin to the hinge region of a macroglobulin. PMID- 4197536 TI - Miliary tuberculosis in British Columbia. AB - The case records were studied of all 48 patients with miliary tuberculosis registered by the British Columbia Division of Tuberculosis Control between 1967 and 1971. Two groups of patients were found, one group of 30 in whom the diagnosis was made during life and antituberculous therapy instituted, and a second group of 18 patients in whom the diagnosis was made only at autopsy and who had received no antituberculous therapy. In the latter group there was a particularly high incidence of concomitant disease; additionally, tuberculin testing, bacteriological search for acid-fast bacilli and chest radiography were frequently neglected. This group consisted mainly of elderly male Caucasians. The disease was characteristically insidious in onset, frequently with non-specific symptoms and physical findings. Fever was a common presenting symptom. Several patients presented with a fulminant illness which, although diagnosed, was not affected by antituberculous therapy and was rapidly fatal. North American Indians showed a high incidence of disease but a low mortality rate, probably owing to their younger age. PMID- 4197537 TI - The prophylaxis of nonindustrial urothelial tumours. AB - Present knowledge concerning carcinogenesis and the natural history of urothelial tumours precludes firm conclusions relative to nonindustrial prophylaxis. However, a number of measures are consistent with current data and may be instituted for those patients with a demonstrated propensity to urothelial tumours. Their acceptability is based on the lack of associated toxicity for the patient. These measures include the elimination of significant infection, cigarettes, artificial sweeteners, analgesic abuse and coffee, the administration of vitamins C and B(6), and in selected cases, the use of thiotepa. It is emphasized that the merit of these steps in altering the natural history of urothelial tumours is uncertain. PMID- 4197538 TI - Analysis of lactic dehydrogenase in the lethal toad hybrid Bufo americanus female times Bufo marinus male. PMID- 4197539 TI - Pyruvate kinase isozymes: a comparative study in tissues of various mammalian species. PMID- 4197540 TI - Avian hepatic esterases, pesticides and diet. PMID- 4197541 TI - The effects of washing, EDTA, magnesium and calcium on oxidative phosphorylation and respiratory rates of mitochondria from heat- and cold-acclimated rats. PMID- 4197542 TI - Australia antigen and primary biliary cirrhosis. AB - Sera from 64 patients with primary biliary cirrhosis have been examined for Australia antigen (Au). On immunodiffusion and immunoelectrophoresis all sera were negative. Using a radioimmunoprecipitation technique 15.6% of sera contained antigen compared with an incidence of 3.1% in matched controls, a significant difference (p = 0.015). Anti-Au was found in 9.4% of patients and in 7.8% of controls. In lymphocyte transformation studies lymphocytes from one of 24 patients with primary biliary cirrhosis transformed on stimulation with an Au rich serum. PMID- 4197543 TI - Association of white cell and red cell antibodies in human sera. AB - Five hundred and eighteen human sera containing known red cell antibodies were tested for lymphocytotoxic antibodies and 81 sera were found to contain them. Thirty-nine antibodies were fully characterized. The frequencies of anti-I, K, V(w), and Wr(a) were significantly greater in those of the 518 sera which also contained white cell antibodies.Four hundred and ninety-four of the 518 sera containing red cell antibodies contained anti-Rh and anti-Kell. The frequency of white cell antibodies in this group was 15% compared with a frequency of 12% in a series of 923 antenatal samples not containing anti-Rh or anti-Kell. The frequencies of different anti-HL-A specificities were compared in the two groups with or without anti-Rh and anti-Kell antibodies. Anti-HL-A 1, 7, and 8 occurred more frequently in the absence of these red cell antibodies and anti-HL-A 12 occurred more frequently in their presence. No correlation was found between particular red cell and white cell antibodies. PMID- 4197544 TI - Electrofocusing of hepatitis B antigen and possible applications to radioimmunoassay techniques. PMID- 4197545 TI - Carcinogenic activity of benzofuran and dibenzofuran analogs of p dimethylaminoazobenzene. PMID- 4197547 TI - [Nursing research in clinical practice]. PMID- 4197546 TI - Epidemilogy of Pseudomonas in a burn intensive care unit. PMID- 4197549 TI - [Bedside nursing. Nursing of terminal patients with knowledge of their condition. Cases of malignant tumors in the field of internal medicine]. PMID- 4197550 TI - [Bedside nursing. A case of renal cancer with nursing problems due to the patient's alien background]. PMID- 4197548 TI - [Discussion. Nursing research in clinical practice]. PMID- 4197551 TI - [Psychological assistance of critically ill patients in the ICU]. PMID- 4197552 TI - [Approach to nursing of young patients with terminal cancer]. PMID- 4197553 TI - [Nursing plan in a case of recurrent cerebellar tumor scheduled for the second surgery within a week following the initial craniotomy]. PMID- 4197554 TI - [Hospital program for cardiac rehabilitation]. PMID- 4197555 TI - [Assistance in functional recovery of daily activities of patients in the chronic stage of neurologic diseases]. PMID- 4197556 TI - [Discussion. Nursing in West Germany and in Japan]. PMID- 4197557 TI - [The government budget for social welfare]. PMID- 4197558 TI - [Diabetes mellitus in the aged]. PMID- 4197560 TI - [Clinical laboratory tests. 1]. PMID- 4197559 TI - [Diabetes mellitus]. PMID- 4197561 TI - [Man and the machine]. PMID- 4197562 TI - [Reevaluation of actual methods in helping patients. 1]. PMID- 4197563 TI - [Nursing psychology. 6. Psychopathology of the patient and his relationship with the nurse]. PMID- 4197564 TI - [Death and nursing. 6. Clinical observation of death. (1). A terminal case of stomach cancer in a middle-aged man who accidentally read his medical records]. PMID- 4197565 TI - [Group dynamics in nursing. 15. Leadership in a crisis situation. (3)]. PMID- 4197566 TI - [Medicine and civilization. 6. Introduction of computers]. PMID- 4197567 TI - [Improved bedpan for young girls]. PMID- 4197568 TI - Enhancement of ampicillin efficacy by peroral levodopa in rat pyelonephritis. PMID- 4197569 TI - Eukaryotes-prokaryotes divergence estimated by 5S ribosomal RNA sequences. PMID- 4197570 TI - On the mode of action of BCG. PMID- 4197571 TI - Prospects for research on schizophrenia. 3. Neurophysiology. Isolation-rearing in primates. PMID- 4197572 TI - Prospects for research on schizophrenia. 3. Neurophysiology. Primate behavioral pathology under field and laboratory conditions. PMID- 4197573 TI - Prospects for research on schizophrenia. VII. Prospects for research in schizophrenia. An overview. PMID- 4197574 TI - Combined bactericidal activity of sodium sulphacetamide and cetrimonium bromide. PMID- 4197575 TI - [Ankle fractures and their sequelae]. PMID- 4197576 TI - Unreduced dislocations. PMID- 4197577 TI - Personal monitoring device for gaseous contaminants. PMID- 4197578 TI - Stability of nitroglycerin in aqueous solution. PMID- 4197579 TI - [Septicemic complications in leukemia and myeloic insufficiency]. PMID- 4197580 TI - Neurofibromatosis in pregnancy. PMID- 4197581 TI - Effects of Ancrod (Arvin) in mice: studies of plasma fibrinogen and fibrinolytic activity. PMID- 4197582 TI - Photon fluence calculations for estimating dose distribution in the thorax. PMID- 4197583 TI - The control of radiation caries. PMID- 4197584 TI - Epilepsy following cerebral abscess. A clinical and EEG study of 70 patients. PMID- 4197585 TI - Generalized sharp and slow wave complexes. Associated clinical features and long term follow-up. PMID- 4197586 TI - The mechanism of drainage of the cerebrospinal fluid. PMID- 4197587 TI - [A failure of experimental metabolic therapy]. PMID- 4197588 TI - [The recovery of a man burned over more than 75 percent of his body]. PMID- 4197589 TI - [Comparative study of therapeutic response of ulcerated and non-ulcerated breast cancers in Negro women in Senegal]. PMID- 4197590 TI - [Sensitivity to antibiotics of Gram-negative bacteria isolated in Dakar]. PMID- 4197591 TI - Histological changes of the pituitary gland in cockerels bearing basal hypothalamic lesions and demonstration of its anti-HCG immunofluorescence reacting cells. PMID- 4197592 TI - Effect of glomerulopressin, oxytocin, and norepinephrine on glomerular pressure in the toad. PMID- 4197593 TI - Failure of mammalian TRH to stimulate thyroid function in the lungfish. PMID- 4197594 TI - Results from evaluating a Canadian regional mental health program. PMID- 4197595 TI - The unit system: current staff attitudes and future directions. PMID- 4197596 TI - Fallcies in using length-of-stay and rturn rates as measure of success. PMID- 4197597 TI - Isolation and characterization of a rabbit adrenal autoantigen. PMID- 4197598 TI - Physicochemical characterization and isolation of rabbit kidney-specific autoantigens. PMID- 4197600 TI - [Serological and pathomorphological aspects of the autoimmunization process in experimental tuberculosis in guinea pigs exposed to fractionated gamma-irradition and treated with isoniazid]. PMID- 4197599 TI - Isolation and characterization of a rabbit non-tissue specific autoantigen which is shared by kidney, heart, adrenal and liver. PMID- 4197601 TI - [Study of the antiviral action of Actinomyces extracts on the multiplication of the respiratory syncytial virus in cell cultures]. PMID- 4197602 TI - [Study of the antibiotic activity of mycetes isolated from the soil of various regions of Bulgaria. I]. PMID- 4197603 TI - [Lysogenic variants of Brucella abortus. 3. A study of the allergic reaction in experimentally infected laboratory animals]. PMID- 4197604 TI - Identification of human reagins isolated with immunosorbent as IgE. PMID- 4197605 TI - Induced homocytotropic antibody to bovine serum albumin in nonatopic dogs. PMID- 4197606 TI - Linkage of thyroxine-binding globulin deficiency to other X-chromosome loci. PMID- 4197607 TI - Biosynthesis of prostaglandin E 2 in human skin: subcellular localization and inhibition by unsaturated fatty acids and anti-inflammatory drugs. AB - The biosynthesis of prostaglandin E(2) (PGE(2)) from [1-(14)C]arachidonic acid has been demonstrated in homogenates and subcellular fractions of human epidermis. This biosynthetic capacity is localized in the microsomal fraction, indicating the presence of an active prostaglandin synthetase system associated with membranes of the skin. The incorporation of (14)C from [1-(14)C]arachidonic acid into PGE(2) by the microsomal fraction was enhanced by EDTA. This apparent increase in (14)C incorporation into PGE(2) in the presence of EDTA could be due at least in part to its chelating properties of removing the divalent cations in the homogenate that enhance the selective formation of PGF(2alpha) and the suppression of the activity of epidermal phospholipase A, which causes the release of nonradioactive fatty acid precursors from endogenous phospholipids. This study has also demonstrated that the formation of PGE(2) from arachidonic acid by the microsomal fraction from human skin could be inhibited by polyunsaturated fatty acids, suggesting a possible regulatory role of fatty acids released from endogenous phospholipids on prostaglandin synthesis in this tissue. The inhibitory effects of some anti-inflammatory drugs on skin microsomal prostaglandin synthetase were also demonstrated in these studies. Results from these studies indicate that the skin is therefore a useful tissue for the study of mechanisms of prostaglandin biosynthesis and the mode of action of various anti-inflammatory drugs. PMID- 4197608 TI - Location of inexchangeable sodium in the nucleus and cytoplasm of oocytes of Bufo bufo exposed to sodium-free solutions. AB - 1. In oocytes exposed to Ringer solution in which Li substitutes for Na, 13-62% Na is inexchangeable with Li.2. Nuclei of oocytes isolated by dissection in salt solutions swell irrespective of the concentration or ionic components of the solution. When isolated in 4% bovine albumin solutions, swelling is negligible.3. When the nuclei of cells exposed to Li are isolated in 4% albumin solution, less than 6% of the inexchangeable Na is found in the nucleus, while 36-88% of it is found in the cytoplasmic fragments remaining after removal of the nucleus.4. When a Li-exposed cell is crushed in a cellophane bag and dialysed against Ringer or Li-substituted Ringer, 86-92% of the inexchangeable Na diffuses out.5. It thus appears that the inexchangeable Na is located almost entirely in the cytoplasm and hardly at all in the nucleus, and is not bound to macromolecules within the cell. PMID- 4197609 TI - An evaluation of combined routes of antibiotic administration in vascular reconstructive surgery. A study of local plus parenteral administration of cephaloridine in dogs. PMID- 4197610 TI - [Macroglobulin-producing chronic lymphocytic leukemia without macroglobulinemia]. PMID- 4197611 TI - [Studies on 125-iodine-labeled synthetic thyrotropin-releasing hormone (TRH)]. PMID- 4197612 TI - Diabetic ketoacidosis in children. PMID- 4197613 TI - Asthma in childhood. PMID- 4197614 TI - The aminoacidopathies. PMID- 4197615 TI - Enzyme blocking in neuro-ophthalmology as tools and diseases. PMID- 4197616 TI - The role of immune reactions in viral encephalitis. PMID- 4197617 TI - A unifying concept of idiopathic epilepsy. PMID- 4197618 TI - Nystagmographical studies in Aland eye disease. PMID- 4197619 TI - The use of animal models for the study of aminoacidopathies. PMID- 4197620 TI - [Tobramycin. In vitro action of a new aminoside. Comparative study in 2 hospital centers]. PMID- 4197621 TI - [Study of parenteral feeding of the infants. Determination of optimal nitrogen ratio]. PMID- 4197622 TI - [Diverticula and pseudo-diverticula of the pharynx simulating an esophageal atresia in newborn infant]. PMID- 4197623 TI - [Duodenal catheter in pediatrics]. PMID- 4197624 TI - Contraction of isolated smooth-muscle cells--structural changes. AB - The contraction of isolated smooth-muscle cells has been correlated with evagination of the cell membrane, a marked change in myofilament orientation, and a decrease in cellular volume. Both localized and full contractions have been elicited in the same cell by varying the intensity of electrical stimulation. These results may be explained by a model of the smooth-muscle cell in which the contractile apparatus extends between attachment sites on the cell membrane that are relatively closely spaced. PMID- 4197625 TI - A protein that binds specifically to the M-line of skeletal muscle is identified as the muscle form of creatine kinase. AB - Published information on the properties of two proteins from chicken muscle, creatine kinase (MM-creatine kinase) and an M-line protein, suggested that they might be identical molecules. Different published procedures were used to purify the two proteins to homogeneity, and the properties of the two preparations were compared. Creatine kinase specific activity increased during purification of M line protein, reaching a value comparable to that of purified MM-creatine kinase. The two proteins migrated identically in two electrophoretic systems and, after electrophoresis, both could be stained for creatine kinase activity. Double immunodiffusion tests with antibody prepared against MM-creatine kinase established the serological identity of the two protein preparations. Immunofluorescent studies showed that antiserum against MM-creatine kinase was bound in a regular pattern at the centers of the A-band regions of isolated myofibrils. These data show conclusively that the M-line protein and MM-creatine kinase are identical. PMID- 4197626 TI - Preservation of normal behavior by enucleated cells in culture. AB - BHK-21 fibroblasts and BSC-1 epithelial cells were enucleated with cytochalasin B. The enucleated cells were trypsinized and replated; their subsequent behavior was monitored by light optical techniques. The results demonstrate that the information necessary for attachment, spreading, shape formation, pinocytosis, contact inhibition, and cell locomotion is present in enucleated cytoplasm. PMID- 4197627 TI - Repeated DNA sequences in the heterochromatic Y chromosome of adult Drosophila melanogaster. AB - DNA isolated from Drosophila melanogaster adults (XX, XY, XXY, XYY) was used in DNA-DNA hybridization experiments on nitrocellulose filters. Filter-bound DNA of "high-heterochromatin" flies (those with one or more Y chromosomes) is more effective in forming hybrid duplexes than is XX DNA. The quantitative difference in hybridization efficiency is due primarily to molecules with a relatively high thermal stability (duplexes that dissociate in the temperature range 80-90 degrees ). Hybridization experiments with DNA samples that have been fractionated into reiterated and unique portions show that the majority of the hybrid duplexes formed involve reiterated DNA. A small, but highly specific, interaction of unique DNA sequences has also been detected in our experiments. These data indicate that a class of repeated DNA sequences is associated with the constitutive heterochromatin, specifically with the Y chromosome of D. melanogaster. Evidence is presented that this same class of molecules, or very similar ones, is to be found in other portions of the genome, presumably in X chromosomal or centromeric heterochromatin. PMID- 4197628 TI - Hydrophobic chromatography: use for purification of glycogen synthetase. AB - A homologous series of omega-aminoalkylagaroses [Sepharose-NH(CH(2))(n)NH(2)] that varied in the length of their hydrocarbon side chains was synthesized. This family of agaroses was used for a new type of chromatography, in which retention of proteins is achieved mainly through lipophilic interactions between the hydrocarbon side chains on the agarose and accessible hydrophobic pockets in the protein. When an extract of rabbit muscle was subjected to chromatography on these modified agaroses, the columns with short "arms" (n = 2 and n = 3) excluded glycogen synthetase (EC 2.4.1.11), but the enzyme was retained on delta aminobutyl-agarose (n = 4), from which it could be eluted with a linear NaCl gradient. Higher members of this series (e.g., n = 6) bind the synthetase so tightly that it can be eluted only in a denatured form. A column of delta aminobutyl-agarose, which retained the synthetase, excluded glycogen phosphorylase (EC 2.4.1.1), which in this column series and under the same conditions requires side chains 5-(or 6)-carbon-atoms long for retention. Therefore, it is possible to isolate glycogen synthetase by passage of muscle extract through delta-aminobutyl-agarose, then to extract phosphorylase by subjecting the excluded proteins to chromatography on omega-aminohexyl-agarose (n = 6). On a preparative scale, the synthetase (I form) was purified 25- to 50-fold in one step. This paper describes some basic features and potential uses of hydrophobic chromatography. The relevance of the results presented here to the design and use of affinity chromatography columns is discussed. PMID- 4197629 TI - Inactive enzyme molecules in aging mice: liver aldolase. AB - Evidence is presented that there is a considerable accumulation of inactive fructose-1,6-diphosphate aldolase (EC 4.1.2.7) in the liver of senescent mice. Liver aldolase was purified from 3-month-old mice and used to immunize rabbits. It was demonstrated with the monospecific antibody thus produced that the liver aldolase of young adult (3 month) and aged (31 month) mice are antigenically identical. With the antibody, inactive enzyme molecules (crossreacting material) in liver homogenate of old mice were detected. The liver aldolase of senescent mice had half as much active enzyme per mg of protein, as well as per antigenic unit, as did the liver aldolase of young adult mice. The accumulation of faulty enzyme molecules may be one of the causes of debilitation leading to senescence and death. PMID- 4197630 TI - Functional correspondence between 30S ribosomal proteins of Escherichia coli and Bacillus stearothermophilus. AB - 30S ribosomal proteins from Bacillus stearothermophilus (B. proteins) have been fractionated and characterized with respect to their ability to replace various E. coli 30S proteins (E. proteins) in the E. coli 30S ribosome reconstitution system. The functional counterparts of all the E. proteins, except S1, S6, S9, and S13, have been tested. In all cases, B. proteins can substitute for E. proteins. Several purified B. proteins are chemically different from their functionally homologous E. proteins. Five B. proteins are immunochemically related to E. proteins; this set includes two proteins that could not be tested in the reconstitution system (S9 and S13). Thus most, if not all, of the E. proteins have functionally equivalent counterparts among B. proteins, even though properties of the two ribosomes are different in several respects. These results suggest that the fundamental structural organization of ribosomes may be the same throughout prokaryotic organisms. PMID- 4197631 TI - Occurrence of specific pollutants in fish in the Forth and Tay estuaries. PMID- 4197632 TI - Algal metabolism and water pollution in the Tay region. PMID- 4197633 TI - Differential activity of homologous chromosome loci in ontogenesis. PMID- 4197634 TI - cis-Dichlorodiammineplatinum(II) (NSC-119 875): preclinical toxicologic evaluation of intravenous injection in dogs, monkeys and mice. PMID- 4197635 TI - Relationship of the structure of mescaline and seven analogs to toxicity and behavior in five species of laboratory animals. PMID- 4197636 TI - [Administration of infusion solutions. 2. Solutions for parenteral feeding and plasma substitutes]. PMID- 4197637 TI - [Pathogens of urinary tract infection and their pathogenetic significance]. PMID- 4197639 TI - Depression of bone marrow and thrombocytopenia associated with chrysotherapy. PMID- 4197638 TI - Multiple DNA polymerases displayed by isoelectric focusing. PMID- 4197640 TI - Rapid, direct tissue culture test for toxigenicity of Corynebacterium diphtheriae. AB - A method for testing toxigenicity of Corynebacterium diphtheriae in tissue culture is described. The technique, called the colony overlay test (COT), involves inoculating material from an isolated colony of C. diphtheriae to a small area on the surface of an agar medium which overlays a monolayer of toxin susceptible HeLa cells. If toxin is produced during incubation at 37 C, it diffuses to the tissue monolayer and destroys the cells below the inoculation site. Twenty-four hours after inoculation, organisms are killed and tissue cells are fixed with formaldehyde. The agar overlay is then removed, and the monolayer is stained with crystal violet. Toxin-affected areas fail to stain or stain poorly. A second plate with antitoxin incorporated in the overlay serves as a control for specificity. Forty-eight strains of C. diphtheriae were tested by the COT, guinea pig, and in vitro, gel diffusion tests. The COT is as specific as the other two tests, is easy to read, and can be used to test large numbers of isolates for toxin action more conveniently than by animal inoculation. PMID- 4197641 TI - Production of staphylococcal enterotoxins A, B, and C in colloidal dispersions. AB - Larger amounts of enterotoxin were produced when Staphylococcus aureus S-6 was grown under still (nonshaken) conditions in a medium that was a paste or gel than were produced in a liquid dispersion with the same colloidal ingredient or in control basal broth (4% NZ Amine-NAK containing 50 mug of thiamine per 100 ml and 1 mg of niacin per 100 ml). Four colloidal ingredients were used which had been previously demonstrated to not support enterotoxin production in buffer. The effect of the type of dispersion occurred earlier than that of the colloidal ingredient, but interactions were found. This effect was not observed when the cells were grown with aeration (shaken). Four other strains of S. aureus followed a similar pattern for enterotoxins A, B, and C, although liquid and paste with cornstarch and carrageenan were the only media compared to the control broth. Enterotoxins A and B were produced earlier by S. aureus S-6, and much greater quantities of enterotoxins were produced for all strains when incubated shaken. PMID- 4197642 TI - The effects of certain inorganic ions on in vitro porphyrin--heme formation. PMID- 4197643 TI - A comparison between immunochemical and physical chemical analyses of the molecular size of urinary proteins. PMID- 4197644 TI - Surface lipid of cells of Pseudomonas aeruginosa and its relation to gentamicin resistance. PMID- 4197645 TI - [Simple juvenile goiter and blood thyrotropin (TSH) levels. Effects of the thyrotropin releasing factor (TRH)]. PMID- 4197646 TI - Extrageniculostriate vision in the monkey. IV. Critical structures for light vs. no-light discrimination. PMID- 4197647 TI - [The basal lamina of the white fat adipose cell and its evolution during weight loss]. PMID- 4197648 TI - [Quantitative aspects of synaptogenesis in the cerebellum of rats undernourished since birth. Comparison with hypothyroid animals]. PMID- 4197649 TI - [Comparative study of the behavior of an anti-estrogen and estradiol in uterine cells]. PMID- 4197650 TI - [Evolution of phenylsulfatase and acid phosphatase activity in the brain and lung in the embryonic development of the chick]. PMID- 4197651 TI - [Detection of aflatoxins by low-temperature luminescence]. PMID- 4197652 TI - [Application of affinity chromatography to the isolation of antigenic fractions of Aspergillus fumigatus which support chymotrypsic activity]. PMID- 4197653 TI - [Application of liquid-phase electrophoresis to the study of the ionized grouping of human platelets sensitive to alkaline phosphatase (phosphate groupings)]. PMID- 4197654 TI - [New information on the external factors in the regulation of the duration of the estral cycle in rats]. PMID- 4197655 TI - [In-vitro culture analysis of the evolution of the morphogenic interdigital necrosis of the chick embryo foot]. PMID- 4197656 TI - [Arginine kinase from lobsters (Homarus vulgaris). New method of preparation of the enzyme]. PMID- 4197657 TI - [Autoradiographic study of the localization of tetrahydroxyflavanediol-C14 in mice]. PMID- 4197658 TI - [Mechanism of hydroxyamphetamine-3H fixation in sections of the rat spleen]. PMID- 4197659 TI - [Common antigenic fractions revealed by immunoprecipitation in gel, between Mycobacterium phlei (Mycobacteriaceae) and Leishmania donovani (Trypanosomidae)]. PMID- 4197660 TI - The acetylcholinesterase of Bungarus fasciatus venom. PMID- 4197661 TI - Immunological studies on globular and elongated forms of electric eel acetylcholinesterase. Effects of hydrolytic enzymes. PMID- 4197662 TI - Treatment of pelvic inflammatory disease in an urban emergency service. PMID- 4197664 TI - [Health insurance--a therapeutic puzzle to be solved by our society]. PMID- 4197665 TI - Thyrotrophin secretion from rat pituitary autografts infused with synthetic thyrotrophin releasing factor. PMID- 4197663 TI - [Efficiency and limits of immunologic methods in the diagnosis of blood coagulation]. PMID- 4197667 TI - A new method of fixation of silicone rubber catheters for long-term hyperalimentation. PMID- 4197666 TI - Pyourachus: an unusual surgical problem. PMID- 4197668 TI - Adjuvants and the reticuloendothelial system. The recall phenomenon of the stimulatory effects of adjuvants with homologous antigen. PMID- 4197669 TI - Mouse IgM antibodies. I. Quantitation of mouse anti-sheep erythrocyte IgM by absorption and radial immunodiffusion. PMID- 4197670 TI - Mouse IgM antibodies. II. Variation in mouse specific sheep erythrocyte antibody and total IgM. PMID- 4197671 TI - Still disease in adults. A cause of prolonged undiagnosed fever. PMID- 4197672 TI - Epilepsy and contact sports. Factors contraindicating participation. PMID- 4197673 TI - Protein calorie malnutrition and intellectual competence. PMID- 4197674 TI - [Antibacterial chemoprevention and therapy in thoracic and vascular surgery]. PMID- 4197675 TI - Oral care in radiation therapy. PMID- 4197676 TI - [Mycological picture card index. 101. Current and revived problems of medical mycology. 1. Human and animal favus, toxic molds, and nematodes in hairy cadavers]. PMID- 4197677 TI - A procedure for chronic microelectrode recording from cerebellar cortex in the awake cat and monkey. PMID- 4197678 TI - Comparative effects of dose protraction and residual injury in dogs and monkeys. PMID- 4197679 TI - Management of gastrointestinal fistulas with parenteral hyperalimentation. PMID- 4197680 TI - [Evaluation of laboratory diagnosis of mastitis in dairy cows in Czechoslavakia in the years 1965-8]. PMID- 4197681 TI - [Etiology of bovine mastitis in Slovakia during the years 1967-1971]. PMID- 4197682 TI - [Biochemical qualities of 14 strains of the genus Klebsiella isolated from bovine mastitis]. PMID- 4197683 TI - [Use of foam preparations in pressurized containers in the treatment of mastitis]. PMID- 4197684 TI - [Changes in the chemical composition of cow's milk which can be used in the diagnosis of subclinical mastitis]. PMID- 4197685 TI - [Relation of milk-production to bovine mastitis]. PMID- 4197686 TI - [Heritability of susceptibility to mastitis in the Slovak pied and Pinzgau cows]. PMID- 4197687 TI - [Calculation of losses in dairy cow efficiency due to mastitis-affected udders]. PMID- 4197688 TI - [Bacteriological findings in udders of dairy cows butchered on the sanitary slaughter line of the Prague Slaughter House]. PMID- 4197689 TI - [Late results of long-term therapy in chronic pyelonephritis]. PMID- 4197690 TI - [Results and experiences in the long-term therapy of chronic pyelonephritis over a period of 11 years in a larger patient material]. PMID- 4197691 TI - [Origins of syphilis]. PMID- 4197692 TI - Symptomatic prognosis in patients with idiopathic hypertrophic subaortic stenosis (IHSS). PMID- 4197694 TI - Identification of ureteral ligation during gynecologic operations. PMID- 4197693 TI - Studies on uterine flushings in the baboon. I. Method of collection, cellular composition, and protein electrophoretic profiles in animals with and without intrauterine contraceptive devices. PMID- 4197695 TI - Immunoglobulin levels and liver function tests in normal and toxemic pregnancies. PMID- 4197696 TI - The pathogenesis of placental infarction. II. An experimental study in the rhesus monkey placenta. PMID- 4197697 TI - An experimental model of pulmonary arterial granulomatous inflammation. AB - An experimental method to investigate pulmonary granuloma formation in the guinea pig was established. Animals sensitized to human serum albumin (HSA) and challenged intravenously with HSA covalently linked to Sepharose 2B beads developed a specific granulomatous response. This intense pulmonary arterial, focally necrotizing, but mainly granulomatous inflammatory reaction developed 5 to 7 days after the administration of the HSA-bead conjugate. Unsensitized animals did not show such extensive inflammation, but rather exhibited a typical foreign body reaction to the bead. In both the experimental and control groups, the inflammatory response was indistinguishable at 14 and 21 days. Thus the initial acute inflammatory reaction was seen only in specifically sensitized animals. On the other hand, HSA alone produced no demonstrable inflammatory lesion. These observations suggest that locally retained antigen may trigger antigen-specific T (thymus-dependent) lymphocytes to release mediators which contribute to granuloma formation. PMID- 4197698 TI - Pseudomonas aeruginosa allergy and humoral antibody-mediated hypersensitivity pneumonia. PMID- 4197699 TI - Scientific Assembly statement. The use of skin tests and serologic tests in histoplasmosis, coccidioidomycosis, and blastomycosis, 1973. PMID- 4197700 TI - [Study of hypophyso-thyroid function using synthetic TRH in thyroid pathology]. PMID- 4197701 TI - [Hyperthyroidism associated with hypopituitarism during the development of a TSH secreting pituitary tumor]. PMID- 4197702 TI - The effect of feeding -2-thienylalanine on phenylalanine metabolism in the rhesus monkey. PMID- 4197703 TI - Coronary artery bypass graft haemodynamics. PMID- 4197704 TI - Direct determination of red cell bound antibody specificity. PMID- 4197706 TI - [Activity of fructose-1,6-diphosphate aldolase in blue-green algae]. PMID- 4197705 TI - Qualitative and quantitative studies on IgG2 globulins in individual human sera with an antiserum capable of differentiating between Gm(n+) and Gm(n-) proteins. PMID- 4197707 TI - [Existence of photochromic regulation system in microorganisms]. PMID- 4197708 TI - Rapid fixation of the left ventricle: continuous angiographic and dynamic recordings. PMID- 4197709 TI - Synthesis of actinomycin D lactam, [1',1'-bis(L-threo- , -diaminobutyric acid)]actinomycin D. PMID- 4197710 TI - Competitive binding to multiple stereospecific binding agents as a means of verifying the identity of a ligand application to cortisol in human umbilical cord blood. PMID- 4197711 TI - Transmissible mink encephalopathy in carnivores: clinical, light and electron microscopic studies in raccons, skunks and ferrets. PMID- 4197712 TI - [Dermatoglyphics of the hand in Recklinghausen's neurofibromatosis]. PMID- 4197713 TI - [Apropos of a case of trisomy D (15)]. PMID- 4197714 TI - [Urethral diverticula in women]. PMID- 4197715 TI - Generalized plane xanthomata with macroglobulinaemia. PMID- 4197716 TI - Reiter's disease and psoriasis. PMID- 4197717 TI - [New data on Hydergine action in arterial pathology of the limbs. Critical study using angiography and liquid crystals]. PMID- 4197718 TI - [Serological reactions with pappataci fever group viruses]. PMID- 4197719 TI - [Influenza A2 (Hong Kong) and ABO and Rh system blood groups]. PMID- 4197720 TI - [Circumscribed periureteral ossification following surgical treatment of retroperitoneal fibrosis (Ormond)]. PMID- 4197721 TI - Central effects of sympathomimetic amines. PMID- 4197722 TI - An automated system for the regulation and medical review of long-term care facilities and patients. PMID- 4197723 TI - Preparation of L-tyrosine-ring- 14 C, L-DOPA-ring- 14 C and related metabolites. PMID- 4197724 TI - Gas-liguid chromatography of parathion metabolites as a sensitive index of induction of liver microsomal mixed-function oxidases. PMID- 4197725 TI - Estimation of eater-extractable Ca in chicken breast muscle by atomic absorption. PMID- 4197726 TI - An assay for the endonucleolytic clevage of RNA to large oligonucleotides. PMID- 4197727 TI - Determination of the Krebs cycle related keto acids of microorganisms by capillary gas chromatography on glass columns. PMID- 4197728 TI - Fine structural changes in the placental membrane of the marmoset with increasing gestational age. PMID- 4197730 TI - Antibacterial action of complexing compounds. The influence of disodium versenate on microorganisms in vitro. PMID- 4197729 TI - Immunologic analysis of noncollagen proteins of human skin. PMID- 4197731 TI - The distribution of blood, serum protein and enzyme groups in a series of Lebanese in Australia. PMID- 4197732 TI - Local antigenic stimulation of guinea-pig mammary gland. PMID- 4197733 TI - Mechanisms of transfer on immunoglobulins into mammary secretion of ewes. PMID- 4197734 TI - Comparisons of immunoglobulin secretion in the salivary and mammary glands of sheep. PMID- 4197735 TI - The diagnosis of tuberculosis in cattle with special reference to bovine PPD tuberculin. PMID- 4197736 TI - [Studies on the tuberculostatic activity on new benzaledhyde and thiophene aldehyde thiosemicarbazones in vitro and in vivo]. PMID- 4197737 TI - The metabolism of ethyl 4-(3,4,5-Trimethoxycinnamoyl) piperazinyl acetate in rats and dogs. PMID- 4197738 TI - [Evaluation of blood levels following oral administration of penicillin V potassium]. PMID- 4197739 TI - Modification by sodium salicylate and paraaminosalyicylic acid of the protein binding and antimycobacterial effect of isoniazid in vitro. PMID- 4197740 TI - [No mutations in Drosophila melanogaster due to 1-allyl-3,5-diethyl-6 chlorouracil (ACIU)]. PMID- 4197741 TI - [Esophageal diverticula]. PMID- 4197742 TI - [Sequential appearance of resistances during spore formation in Bacillus subtilis]. PMID- 4197743 TI - [Action of gallium sulfate on cellular immunity]. PMID- 4197744 TI - [Isolation and description of a vaccinating antigen present in the culture supernatant of Yersinia pestis (strain EV-40)]. PMID- 4197745 TI - [Retention of particles in bronchial cells: possible relationships with inhaled carcinogens]. PMID- 4197746 TI - The pancreatic -cell recognition of insulin secretagogues. IV. Islet uptake of sulfonylureas. PMID- 4197747 TI - Serum autoantibodies and immunoglobulins in hepatitis-associated antigen (HAA) positive and -negative liver disease. AB - Serum immunoglobulin G, A, and M and serum antinuclear, mitochondrial, and smooth muscle antibody have been measured in 223 patients with hepatitis-associated antigen (HAA)-positive and -negative acute and chronic liver disease. In patients with acute hepatitis, chronic persistent hepatitis, and primary liver cell carcinoma, these indices failed to show any significant differences. However, in the group with chronic aggressive hepatitis the patients who were HAA negative had significantly higher levels of serum IgG, much higher titres of smooth muscle antibody, and often antinuclear and mitochondrial antibodies which were not found in the HAA-positive patients from this group. This suggests that different pathogenic mechanisms may be operative in HAA-positive and -negative chronic aggressive hepatitis. PMID- 4197748 TI - Gel filtration studies on immunoreactive gastrin in serum from Zollinger-Ellison patients. AB - Sera from 15 patients with the Zollinger-Ellison syndrome were subjected to gel filtration on Sephadex G-50 superfine columns (10 x 2000 mm). The concentration of gastrin in the effluent was determined by a sensitive radioimmunoassay. Immunoreactive gastrin was eluted in four components in 14 sera. (1) Component I, eluted in the same position as proinsulin, constituted 9.7 +/- 1.2 (mean +/- SEM)% of the total immunoreactivity. (2) Component II (;big gastrin') eluted between proinsulin and insulin constituted 57.8 +/- 4.1% (mean +/- SEM) of immunoreactive gastrin. In three sera with the highest concentration of gastrin, component II appeared biphasic. (3) Component III (;little gastrin') was distributed in two peaks; the first one eluted in the same position as the heptadecapeptide gastrin II made up 17.4 +/- 2.7 (mean +/- SEM)% of the total immunoreactivity; the second one eluted in the same position as gastrin I constituted 9.5 +/- 1.3 (mean +/- SEM)%. (4) Component IV (;minigastrin') was eluted immediately before the salt peak and constituted 5.6 +/- 1.4 (mean +/- SEM)%. In one serum only components I and II were present. After incubation with trypsin all immunoreactivity in components I and II was converted to heptadecapeptide-like gastrins.The findings suggest that immunoreactive gastrin in serum from Zollinger-Ellison patients is circulating in at least four components of different molecular size. PMID- 4197749 TI - Isolation of Rickettsia rickettsi in primary bone marrow cell and circulating monocyte cultures derived from experimentally infected guinea pigs. AB - Rickettsia rickettsi was isolated and propagated in primary cell cultures derived from experimentally infected guinea pigs. Organisms were recognized as early as 3 days after cultures were initiated. PMID- 4197750 TI - Multiplicity of Scrapie virus in infected mouse spleen cells in vivo. AB - Subpopulations of spleen cells from scrapie virus-infected mice were used to determine the average virus content of infected cells in vivo at a time when virus was rapidly increasing in titer in lymphoreticular tissues. Comparison of the mean lethal doses of lysed to intact cells indicated averages of 2 to 6 infectious units per infected cell. In another experiment, preparations of cytoplasmic nucleic acids extracted from spleen cells of infected mice had no detectable infectivity, which suggests that the transmissible form of the virus is not a free nucleic acid. PMID- 4197751 TI - The pharmaceutical market and prescription drugs in the Federal Republic of Germany: cross-national comparisons. PMID- 4197752 TI - [Morphometric analysis of mitotic chromosomes in Drosophila melanogaster (idiogram and heterochromatic regions)]. PMID- 4197753 TI - A method for measurement of antibiotics in human interstitial fluid. PMID- 4197755 TI - Shigellosis due to Shigella dysenteriae. 1. Relative importance of mucosal invasion versus toxin production in pathogenesis. PMID- 4197754 TI - Immunologic response of man to group B meningococcal polysaccharide vaccines. PMID- 4197756 TI - Effect of rifampicin on delayed-hypersensitivity reactions. PMID- 4197757 TI - Adherence of Neisseria gonorrhoeae to urethral mucosal cells: an electron microscopic study of human gonorrhea. PMID- 4197758 TI - Treatment of funnel-web spider bite. PMID- 4197759 TI - [Drug therapy of Parkinson's syndrome. Clinical long-term study using L-dopa and the drug conbination L-dopa-decarboxylase inhibitor]. PMID- 4197760 TI - Mutagenic DNA polymerase in B. subtilis. PMID- 4197761 TI - Quantitating cholinergic receptor molecules. PMID- 4197762 TI - Laboratory diagnosis of multiple sclerosis. Elevation of immunoglobulin G in cerebrospinal fluid. PMID- 4197763 TI - [Feeding of patients following laryngectomy]. PMID- 4197764 TI - Diagnosis of meningococcal arthritis by immunoelectrophoresis of synovial fluid. AB - In a case of meningococcal arthritis, the organism was identified promptly through examination of synovial fluid by countercurrent immunoelectrophoresis. PMID- 4197765 TI - Preparation of solid-phase immunosorbents by coupling human serum proteins to cyanogen bromide-activated agarose. AB - The method of preparing solid-phase immunosorbents by covalently attaching proteins from whole human serum to cyanogen bromide-activated agarose has been investigated to determine optimum concentrations of cyanogen bromide and protein, and the optimum pH for the maximum attachment of proteins from serum. Two systems in which the above immunosorbents have proved useful are described: the removal of antibodies to normal serum proteins from anti-hepatitis B serum and the removal of light chain antibodies from anti-human immunoglobulin M serum. PMID- 4197766 TI - Aflatoxin production of species and strains of the Aspergillus flavus group isolated from field crops. AB - Peanuts, cottonseed, rice, and sorghum from Texas were sampled over a 3-year period. To insure adequate isolation of alfatoxin-producing species of fungi, low quality lots were sampled at a rate greater than their respective proportional representation. Aflatoxins were found each year in peanut and cottonseed and were found in 2 of 3 years in rice and sorghum. Aflatoxins were detected in all four crops. The Aspergillus flavus group was much more prevalent in peanut and rice than in cottonseed and sorghum. Of the isolates of the A. flavus group, 96% from peanuts, 79% from cottonseed, 49% from sorghum, and 35% from rice produced aflatoxins. The average toxin production of isolates from rice was much less than that from peanuts, cottonseed, or sorghum. More than 90% of all isolates of the A. flavus group were identified as the species A. flavus. A. parasiticus was isolated from all four crops. Only A. parasiticus produced aflatoxin G. PMID- 4197767 TI - Indirect fluorescent-antibody method for the identification of Corynebacterium vaginale. AB - The indirect fluorescent-antibody technique was employed in an attempt to develop a rapid method of identification of Corynebacterium vaginale. Six reference strains and ten clinical isolates selected on the basis of morphology and conventional biochemical tests were compared. Antisera were prepared in rabbits against the six reference strains. The most satisfactory antiserum was that prepared using strain 14018 grown diphasically (14018 Di) as the antigen. Certain of the antisera did exhibit a cross-reacting titer when reacted against Corynebacterium diptheriae, Corynebacterium xerosis, or Lactobacillus acidophilus. However, antisera adsorbed with these bacteria did not exhibit a significant decrease in titer when reacted against the homologous strain. Various other species of Corynebacterium as well as species of Nocardia, Actinomyces, Hemophilus, and Streptococcus did not fluoresce with the antisera. A specific antiserum was prepared by adsorbing anti-14018 Di with L. acidophilus. The adsorption removed the cross-reacting antibody but did not affect the staining reaction with C. vaginale strains. All reference strains and clinical isolates characterized as C. vaginale gave a definite positive reaction with the adsorbed anti-14018 Di. The specificity of the reactions was assessed by adsorbing the antiserum with the homologous strain. The data suggest that the indirect staining method will be of value in the rapid presumptive identification of C. vaginale. PMID- 4197768 TI - Control of surface wound infection: skin versus synthetic grafts. AB - Auto-, iso-, or xenografts of skin and synthetics placed on surface wounds freshly contaminated with Pseudomonas aeruginosa stabilizes the wound bacterial population in rats over a 24-h period. When these wounds contained a bacterial contamination established for 24 h prior to grafting, only skin and the synthetic polyhydroxyethylmethacrylate were effective in lowering the initial bacterial concentration. Polyurethane foam and nylon velour were not effective in the established infection model. Skin placed on a contaminated wound for 2 h or longer appeared to equilibrate with the underlying muscle so that the bacterial count per milligram of skin was similar to that of the muscle. It was suggested that this preparation would be useful to obtain an estimate of surface contamination without biopsy of the infected muscle. Skin grafts in place for 2 h significantly lowered the bacterial count in a wound with an established infection. A second decrease occurred between 4 and 24 h after grafting. Histological studies of contaminated and exposed panniculus muscle showed that leukocytes tend to migrate from the muscle surface to its base. Skin grafts and polyhydroxyethylmethacrylate appear to reverse the white cell migration so that the cells move toward the surface of the muscle with preservation of normal staining characteristics in the muscle. It is suggested that this alteration in cell movement after graft application might modify the white cell function and result in a greater bactericidal activity. Apparently, grafts lower bacterial levels in an established infection by modifying the host response to the surface contamination. PMID- 4197769 TI - Culture of Ethiopian strains of Borrelia recurrentis. AB - A number of standard bacteriological media with supplements were tested for their ability to support in vitro growth of Ethiopian strains of Borrelia recurrentis. Propagation of 18 out of 21 strains occurred in Trypticase soy yeast broth to which bovine albumin (fraction V), N-acetyl glucosamine, and sodium pyruvate had been added. This medium supported a population of 10(7) organisms per ml and yielded a harvest of four to five times the original inoculum during the logarithmic phase of growth. Maximal yield varied from 1.4 x 10(7) to 3.4 x 10(7) organisms per ml. Generation time in optimal media was 11.3 h. Lesser multiplication of organisms occurred in other media tested. Strains from primary cultures were infective for the green monkey. Recovery of viable organisms from subculture has not been successful. PMID- 4197770 TI - Preservation of mycobacteria: 100 percent viability of suspensions stored at -70 C. AB - Our earlier studies on long-term preservation of mycobacteria have been expanded to include other species in this genus. Mycobacterium kansasii and M. marinum, like mammalian tubercle bacilli and BCG, survive much better when stored at -70 C. By statistical analysis, M. gordonae, M. scrofulaceum, M. xenopi, M. avium, M. intracellulare, M. terrae, M. fortuitum, and M. smegmatis survived equally well at -20 C or -70 C; however, viable counts of all strains stored at -20 C were always lower than those of paired suspensions stored at -70 C, suggesting that the lower temperature is preferable for prolonged storage periods. Advantages of preservation at -70 C in Tween-albumin liquid medium are: (i) 100% viability of bacterial populations for long periods, (ii) highly reproducible inocula for animal experiments, (iii) minimal clonal selection of undesirable mutants, (iv) maintenance of genetic characteristics, and (v) adaptability to a "seed lot" system. On the basis of available information, a discussion of lyophilization versus freezer storage is presented. PMID- 4197771 TI - Cicatricial pemphigoid. Immunofluorescence investigations. PMID- 4197772 TI - Gold sodium thiomalate treatment of pemphigus. PMID- 4197774 TI - The middle temporal visual area(MT)in the bushbaby, Galago senegalensis. PMID- 4197773 TI - Applications of a simplified triple-test cross. PMID- 4197775 TI - Acute myelomonocytic leukemia with macroglobulinemia, Bence Jones proteinuria, and hypercalcemia. PMID- 4197776 TI - The role of iron in bacterial infections, with special consideration of host tubercle bacillus interaction. PMID- 4197777 TI - [Nutrition counseling in Kenya - German nurses try to help - hope and resignation in Homa Bay]. PMID- 4197778 TI - [Therapy of uremic osteopathy. II. Effect of 5,6-trans-25-hydroxycholecalciferol in terminal kidney insufficiency]. PMID- 4197779 TI - Metabolism and elimination of sulphite by rats, mice and nonkeys. PMID- 4197780 TI - Effects of methylmercuric chloride on the progeny of mice and rats treated before or during gestation. PMID- 4197781 TI - More meditations of MSG. PMID- 4197782 TI - Experimental autoimmune damage to rabbit male accesory glands. PMID- 4197783 TI - Asymptomatic ossification of the posterior longitudinal ligament of the cervical spine. Incidence and roentgenographic findings. PMID- 4197784 TI - Anti-nociceptive activity of clonixin in rhesus monkeys. PMID- 4197785 TI - [When does life start?]. PMID- 4197786 TI - [Oral contraception--what is it precisely?]. PMID- 4197787 TI - [A piece of tissue or--a person?]. PMID- 4197788 TI - [On Paragraph 218 - voices, viewpoints, positions]. PMID- 4197789 TI - [Worldwide danger - venereal diseases]. PMID- 4197790 TI - [Comprehensive nursing care. VI. The team leader's role in team nursing]. PMID- 4197791 TI - [Difficulties and prospects in nursing]. PMID- 4197792 TI - [Co-responsibility of student nurses: constructive criticism of bloc education]. PMID- 4197793 TI - [Comprehensive nursing care. VII. Role of the head nurse in comprehensive nursing care]. PMID- 4197794 TI - [Individual, comprehensive nursing care]. PMID- 4197795 TI - [Housekeeping under discussion]. PMID- 4197796 TI - [Simultaneous determination of partial renal function by the radioisotope method using I-131-hippuran and Yb-169-EDTA]. PMID- 4197797 TI - Electron microscopic and serological studies on simian virus S.A. 11 and the "related" O agent. PMID- 4197799 TI - Metabolic characteristics of 241 Am in the adult baboon. PMID- 4197798 TI - Neurophysiology of color vision. PMID- 4197801 TI - [Elastic fibers distribution in the disc of the temporormandibular joint of the marmoset (Callithrix jacchus L. 1758)]. PMID- 4197800 TI - [Hereditary systemic diseases of the skeleton]. PMID- 4197802 TI - [Effect of EDTA compounds on root canal dentin]. PMID- 4197803 TI - [Episode of acute pulmonary inflammation of hallucinatory states during Brailsford-Morquio's disease]. PMID- 4197804 TI - Carbonic anhydrase quantity of red blood cells in morbus basedowii. PMID- 4197805 TI - [Adverse effects of longtime dihydrotachysterol substitution therapy]. PMID- 4197806 TI - [Adverse effects of long-term glucocorticoid therapy on bone metabolism]. PMID- 4197807 TI - [Standarization of therapy in hemaoblastoses and malignant lymphomas as shown on the sample of lymphogranulomatosis]. PMID- 4197808 TI - Bile reflux gastritis. Diagnosis, medical and surgical therapy. PMID- 4197809 TI - [Comparative sensitivity in vitro to penicillin and erythromycin of gonococci isolated in 1965-1966 and 1971]. PMID- 4197810 TI - [Pathogenicity of meningococcal L forms obtained under the influence of penicillin]. PMID- 4197811 TI - [Inhibition of the beta-lactamase-like activity of kidney tissue of white mice by a combination of phenoxymethyl penicillin and phenoxymethyl penicillin sulfoxide]. PMID- 4197812 TI - [Formation of beta-lactam antibiotics by actinomycete cultures]. PMID- 4197813 TI - [Comparative characteristics of pigmented and nonpigmented variants of Act. aureofaciens LSB-2201]. PMID- 4197815 TI - Studies on prephenoloxidase-activating enzyme from cuticle of the silkworm Bombyx mori. II. Purification and characterization of the enzyme. PMID- 4197814 TI - Studies on prephenoloxidase-activating enzyme from cuticle of the silkworm Bombyx mori. I. Activation reaction by the enzyme. PMID- 4197816 TI - Preparation of rubella virus antigens for immunodiffusion by mild extraction of infected cells with a neutral detergent. PMID- 4197817 TI - Immunochemical studies of Sindbis virus variants. PMID- 4197818 TI - [Vascular structure of the dental pulp in deciduous and permanent teeth in primates]. PMID- 4197819 TI - An absolute requirement for insulin in the control of hepatic glycogenesis by glucose. PMID- 4197820 TI - Sulfhydryl reactivity of organic nitrates: biochemical basis for inhibition of glyceraldehyde-P dehydrogenase and monoamine oxidase. PMID- 4197821 TI - Kinetic parameters of human carbonic anhydrase B as determined from NMR linewidths of 13 C in CO 2 and HCO 3 - . PMID- 4197822 TI - Metabolism of 35 S-methionine and 35 S-cystine in the pregnant rhesus monkey. PMID- 4197824 TI - The management of carcinoma of the breast by radical supervoltage radiation. PMID- 4197823 TI - Non-pulmonary surgical tuberculosis. PMID- 4197825 TI - Chromatography of Drosophila tRNA on BD-cellulose. PMID- 4197826 TI - The immune response to thetaX 174 in man. I. Primary and secondary antibody production in normal adults. PMID- 4197828 TI - [Regulatory mechanims of the hypothalamo-hypophysial-thyroid system in hyperthyroidism-reaction in TRH (TSH releasing hormone) test]. PMID- 4197827 TI - A comparison of in vitro, immunosuppressive and clinical effects of goat and horse anti-human thymocyte globulin in Macaca monkeys. PMID- 4197829 TI - Self-inflicted rotation osteotomy of the tibia. PMID- 4197832 TI - Stereotaxic treatment of frontal-lobe and centrencephalic epilepsy. PMID- 4197830 TI - Immunoglobulin molecules on the surface of activated T lymphocytes in the rat. AB - Lewis strain rat lymphocytes were exposed in vitro to a variety of specific and nonspecific blastogenic stimuli. The surfaces of the transformed lymphocytes were examined by indirect immunofluorescence for the presence of T cell antigens and immunoglobulin molecules. More than 90% of lymphocytes that underwent blast transformation after exposure to foreign histocompatibility antigens (mixed lymphocyte reaction; in vitro allograft reaction), purified tuberculin, phytohemagglutinin (PHA), and concanavalin A (Con-A) had T cell antigenic markers on their surfaces. 70-92% of the antigen-stimulated blast cells also had readily detectable surface immunoglobulin molecules, whereas less than 3% of the PHA- and Con-A-activated cells were Ig(+). Pokeweed mitogen (PWM) appeared to activate both B and T cells, but the T cells did not have detectable surface immunoglobulin molecules. Nonactivated control cultures contained T(+)Ig(-) lymphocytes almost exclusively. The results suggest that thymus-dependent rat lymphocytes express increased amounts of detectable immunoglobulin on their surface in response to specific stimulation with antigen. It is postulated that the acquisition of immunological competence by activated T cells may be related to this expression of surface immunoglobulin. PMID- 4197831 TI - Production of a runting syndrome and selective A deficiency in mice by the administration of anti-heavy chain antisera. AB - Conventional Swiss mice were treated from birth with intraperitoneal injections of anti-immunoglobulins in an attempt to create an experimental dysgammaglobulinemia. Mice treated with anti-gammaM were immunologically suppressed in all immunoglobulin classes as determined by serum antibody titers, splenic plaque-forming cells, serum immunoglobulin levels, and immunofluorescent analysis of plasma cells in lymphoid tissues. Treatment immediately after birth with high concentrations of anti-gammaM leads to a developmental arrest characterized by severe immunosuppression, failure to gain weight, and premature death. The pathogenesis of anti-gammaM runting syndrome is unknown. Animals similarly treated with anti-gammaG, anti-gammaA, or control normal goat or rabbit gamma-globulins developed normally. The frequency of occurrence and severity of anti-gammaM-induced runting syndrome is dependent upon the concentration of anti gammaM-globulin administered. Administration of anti-gammaA resulted in a selective gammaA deficiency that was characterized by a marked reduction in serum gammaA and an absence of gammaA-containing cells in the spleen. However, essentially normal numbers of plasma cells were found in the gastrointestinal lamina propria of anti-gammaA-treated animals concomitantly with suppressed levels of gammaA in intestinal fluids. PMID- 4197833 TI - Value of normothermic perfusion, hypothermic perfusion, and durotomy in the treatment of experimental acute spinal cord trauma. PMID- 4197834 TI - Neurophysiological assessment of afferent and efferent conduction in the injured spinal cord of monkeys. PMID- 4197835 TI - Electrical properties of toad sartorius muscle fibres in summer and winter. AB - 1. The area and circumference of surface fibres of sartorius muscles were measured from photomicrographs of frozen sections of whole muscles, and compared with the values obtained assuming a circular cross-section. The latter assumption gave an over-estimate of the mean area of 28%, but only a 2% over-estimate of the circumference. In isolated, single fibres, the assumption gave over-estimates of 25 and 6%, of area and circumference respectively.2. The passive electrical properties of fibres were different in summer and winter. The mean internal resistivity, membrane resistance and membrane capacitance were 147 Omega.cm, 7.6 kOmega.cm(2) and 4 muF/cm(2) in summer, and 194 Omega.cm, 3.9 kOmega.cm(2) and 6.7 muF/cm(2) in winter, in fibres of comparable diameters in situ. In single fibres in summer, the mean values were 120 Omega.cm, 8.6 kOmega.cm(2) and 3.6 muF/cm(2).3. In glycerol-treated fibres the mean specific membrane capacitance was 1.0 muF/cm(2) in summer and 2.0 muF/cm(2) in winter. The internal resistivity and specific membrane resistance were 167 Omega.cm and 8.9 kOmega.cm(2) in summer, and 232 Omega.cm and 3.9 kOmega.cm(2) in winter.4. Early after depolarizations were recorded in glycerol-treated fibres which had a low membrane capacitance, did not twitch and showed little ;creep'. Electron micrographs of glycerol-treated fibres showed disruption of the transverse tubular system and sarcoplasmic reticulum.5. After exposure of muscles to 400 mM urea or acetamide for 1 hr, muscle fibres did not twitch and had a reduced membrane capacitance in Ringer solution. PMID- 4197836 TI - Incorporation of ethanolamine into phosphatidylethanolamine in mouse liver by exchange reaction. PMID- 4197837 TI - [The heart as an efferent regulator of the blood clotting process and fibrinolysis]. PMID- 4197838 TI - [Clinical use of the whole body radiometry technic to study Na24 metabolism]. PMID- 4197840 TI - [3-Speculum retractor for operations on the biliary tract]. PMID- 4197839 TI - [Surgical management of duodenal diverticula associated with other diseases of the digestive organs]. PMID- 4197841 TI - [Daily rhythm of the biogenic amine (histamine, serotonin) level in the blood of persons normally and under an altered work regimen]. PMID- 4197842 TI - [Guide lines for the treatment of patients with the apallic and postopallic syndrome]. PMID- 4197843 TI - [Quantitative determination of human fibrinogen with the immunodiffusiometric method]. PMID- 4197845 TI - Oocysts of Isospora papionis in the skeletal muscles of chacma baboons. PMID- 4197844 TI - Progesterone-sensitive loci for blockade of ovulation in the hamster. PMID- 4197846 TI - The experimental transmission of Theileria ovis by Rhipicephalus evertsi mimeticus and R. bursa. PMID- 4197848 TI - [Jaw orthopedics--a biological problem]. PMID- 4197847 TI - Some protozoan parasites of tragelaphine antelopes in South Africa with special reference to a Babesia sp. in a bushbuck and a Trypanosoma Theileri-like parasite in a Nyala. PMID- 4197849 TI - Mycobacteria of surgical interest. PMID- 4197850 TI - The present status of one-stage pharyngo-esophageal diverticulectomy. PMID- 4197851 TI - Tyrosinase in melanized melanosomes. PMID- 4197852 TI - The value of electrodiagnostic tests in pigmentary retinopathy. PMID- 4197853 TI - Immunological responsiveness and tolerance of marmoset lymphoid tissue in vitro. PMID- 4197854 TI - Modification of hyperacute xenograft rejection by intra-arterial infusion of disodium ethylenediaminetetraacetate. PMID- 4197855 TI - Disturbances of coagulation mechanism in protein-calorie malnutrition. PMID- 4197857 TI - Comparative histoenzymatic studies on the distribution of alkaline and acid phosphatases in the liver and pancreas of a few birds viz., Upupa epops (fam. Upupidae), Cinnyris asiatica (fam. Nectariniidae) and Halcyon smyrnensis (fam. Alcedinidae). PMID- 4197856 TI - [Renal involvement in systemic erythematodes: correlation of structural and functional lesions--prognostic and therapeutic consequences]. PMID- 4197858 TI - Linear dichroism and anomalous dispersion of the birefringence on sperm heads. PMID- 4197859 TI - Lysozyme in Paneth cell secretions. PMID- 4197860 TI - Hypokinetic effects on the RNA and protein metabolism in motoneurons of anterior horns of the rat spinal cord. PMID- 4197861 TI - [Immunhistological demonstration of Australia antigen in the liver]. PMID- 4197862 TI - [Influence of phenazinmethosulfate (PMS) on the histochemical demonstration of succinate dehydrogenase]. PMID- 4197863 TI - Polarographic investigations on Pb ++ trapping by rat liver homogenate. PMID- 4197864 TI - [Functional development of the golden hamster lung. Electron microscopy and histochemical studies of lung alveoli]. PMID- 4197865 TI - [Microspectrophotometric method for quantitative acetylcholinesterase activity determination in tissue sections]. PMID- 4197867 TI - Testicular leucine aminopeptidase in different vertebrates. PMID- 4197866 TI - Differentiation of noradrenaline and adrenaline containing cells in the adrenal medulla by the trihydroxyindole histochemical reaction. PMID- 4197868 TI - [Histochemical study on the differentiation of the duodenal epithelium in chick embryos]. PMID- 4197869 TI - [Demonstration of the myoepithelial cells in the bovine udder]. PMID- 4197871 TI - Changes in antithrombin 3 levels following cessation of anticoagulant therapy. PMID- 4197870 TI - Effects of alprenolol and isosorbide dinitrate in angina pectoris. A comparative study with methodological considerations. PMID- 4197872 TI - A new hemodialysis console. I. General description. PMID- 4197873 TI - Alprenolol alone and in conjunction with pentanitrol in angina pectoris. A double blind study with exercise tests. PMID- 4197874 TI - Experimental zinc chloride ocular injury and treatment with disodium edetate. PMID- 4197875 TI - Immunoglobulins in tears. PMID- 4197876 TI - Analgetic activities of etoxadrol in the rhesus monkey and in mice. PMID- 4197877 TI - Recovery of patients after intensive care for blunt injuries. PMID- 4197878 TI - Biliary excretion of 14 C-edrophonium and its glucuronide metabolite in Gunn rats. PMID- 4197879 TI - Interaction between drugs using three-dimensional isobolographic interpretation. PMID- 4197880 TI - Vascular reactions in the musculo-cutaneous area during the hypertension induced by acetylcholine in atropinized dogs. PMID- 4197881 TI - Pharmacological investigations with benzoctamine (Tacitin), a new psycho-active agent. PMID- 4197882 TI - Simple methods for plating single vegetative cells of, and for replica-plating, filamentous blue-green algae. PMID- 4197883 TI - The persistence of courtship stimulation in Drosophila melanogaster. PMID- 4197884 TI - Regulation of gene function: a comparison of enzyme activity levels in relation to gene dosage in diploids and triploids of Drosophila melanogaster. PMID- 4197885 TI - Properties of salivary basic proteins showing polymorphism. PMID- 4197886 TI - Alternative interpretation of the molecular structure and somatic genetics of acid phosphatase-1 in Tetrahymena pyriformis. PMID- 4197887 TI - IgA-induced anaphylactic transfusion reactions: a report of four cases. PMID- 4197888 TI - The invasion of burned skin by Pseudomonas aeruginosa. PMID- 4197889 TI - Haemophilus influenzae cellulitis. Case presentation and review of the literature. PMID- 4197890 TI - Therapeutics XXII. Drug interaction. I. PMID- 4197891 TI - Immune globulin characterization of complement fixing antibodies in histoplasmic infection. PMID- 4197892 TI - Left ventricular angiography as a function test. PMID- 4197893 TI - The Ig class and light chain type of the long acting thyroid stimulator. PMID- 4197894 TI - Human chorionic somatomammotrophin and its clinical significance. PMID- 4197895 TI - Incorporation of 32 P during early amphibian embryogenesis. PMID- 4197896 TI - The biochemical properties of esterases in Cepaea (Mollusca: Helicidae). PMID- 4197897 TI - Combinations of the effect of radiotherapy, alkylating agents and phytohemagglutinin on sarcoma 180 in Swiss mice. PMID- 4197898 TI - Characteristics of the reverse passive respiratory reaction in Rhesus monkeys. PMID- 4197899 TI - Characterization of an Escherichia coli mutant deficient in dihydrolipoyl dehydrogenase activity. AB - A mutant of Escherichia coli deficient in dihydrolipoyl dehydrogenase (DHL) activity has been isolated and its characteristics have been studied. The activities of the pyruvic dehydrogenase (PDC) and alpha-ketoglutaric dehydrogenase complexes (KDC) are not present in extracts of the mutant unless purified dihydrolipoyl dehydrogenase is added. Experiments with antiserum to DHL have shown that cross-reacting material exists in mutant extracts. This suggests that the dihydrolipoyl dehydrogenase mutation (dhl(-)) is a missense structural mutation. The mutation maps very close to, if not adjacent to, the ace loci, and is not linked to the suc loci. This means the dhl locus is grouped with the genes for the other components of the PDC and not with the genes for KDC. The mutation is also transducible into prototrophic strains, demonstrating that no prior mutation is necessary for the DHL activity deficiency to exist. This evidence is consistent with the idea that there is only one gene for DHL and is supported by previous biochemical studies which have shown that DHL preparations from either enzyme complex are electrophoretically and immunochemically indistinguishable. Possible mechanisms for the genetic and metabolic control of DHL, PDC, and KDC are discussed. PMID- 4197900 TI - A bifunctional enzyme in Pseudomonas aeruginosa: a new pattern in the organization of enzymes concerned with phenylalanine and tyrosine biosynthesis. AB - Two isozymes of chorismate mutase (CA mutase(1) and CA mutase(2)) and two isozymes of prephenate dehydratase (PPA dehydratase(1) and PPA dehydratase(2)) have been found in Pseudomonas aeruginosa. The activities CA mutase(2)-PPA dehydratase(2) catalyzing phenylalanine biosynthesis have been purified almost 40 fold and were found to be associated as a bifunctional enzyme or an enzyme complex. The enzymes specific for tyrosine biosynthesis did not appear to manifest such physical association. Thus, the organization of enzymes concerned with phenylalanine and tyrosine biosynthesis in P. aeruginosa is unique and is unlike most other organisms. Single site mutants have been isolated which have lost both CA mutase(2)-PPA dehydratase(2) activities resulting in a requirement for phenylalanine for growth. Single site revertants of these mutants regained both these activities simultaneously and were able to grow on minimal medium. A mutant, r(6), was also isolated which had normal CA mutase(2) but lacked PPA dehydratase(2) activity. PMID- 4197901 TI - Chemical analysis of cell walls and autolytic digests of Bacillus psychrophilus. AB - The amino acid composition of isolated cell walls of Bacillus psychrophilus has been determined before and after extraction of protein with ethylenediamine tetraacetic acid at 45 C. This revealed that the peptidoglycan consists of Ala, Lys, and Glu in a molar ratio of 3:1:2. By using autolytic digests of log-phase cell walls, it was possible to detect 14 ninhydrin-positive degradation products. Chemical analyses of the seven major bands from these digests indicated that the amino acid sequence of the peptide subunit in the murein of this organism consists of muramyl-l-alanyl-gamma-d-glutamyl-l-lysyl- d-alanine, and the linkage between adjacent peptides is supplied by a second d-glutamic acid which is bound to the sigma-amino group of lysine and the carboxyl group of the d-alanine through its amino group. The nature of the solubilized wall fragments indicates that each of the peptide bonds in the murein is hydrolyzed by autolysins except the l-alanyl-gamma-d-glutamyl linkage. PMID- 4197902 TI - A growth initiation factor for host-independent derivatives of Bdellovibrio bacteriovorus. AB - Host-independent (H-I) derivatives of Bdellovibrio bacteriovorus 109 Davis could not be isolated when concentrated suspensions of host-dependent (H-D) cultures, washed free of spent medium, were plated on host-free media. However, H-I colonies did appear when spent broth was incorporated into the isolation medium, indicating the presence of a factor in the spent medium essential for the growth of H-I cells. This growth factor (GIF) was also present in cell-free extracts of Escherichia coli and a variety of other microorganisms including H-D and H-I derivatives of strain 109 Davis. GIF was heat stable, non-dialyzable, and present in both soluble and particulate fractions of extracts. Heating of extracts at 70 C for 10 min resulted in 10- to 40-fold stimulation in GIF activity, and evidence for a heat-labile inhibitor was obtained. Colonies appearing on host-free medium in these experiments were shown to be those of typical H-I derivatives by isolation and subsequent host-independent cultivation of these organisms. GIF was a conditional requirement dependent on age and size of inoculum for all H-I derivatives characterized. Although GIF stimulated the growth of washed exponential phase cells transferred to fresh medium, it was not essential for growth. However, it was essential for the initiation of growth of washed stationary phase cells from small inocula transferred to fresh medium. It is proposed that GIF is required to initiate growth of metabolically quiescent cells. PMID- 4197903 TI - Fatty acids of Myxococcus xanthus. AB - Fatty acids were extracted from saponified vegetative cells and myxospores of Myxococcus xanthus and examined as the methyl esters by gas-liquid chromatography. The acids consisted mainly of C(14) to C(17) species. Branched acids predominated, and iso-pentadecanoic acid constituted half or more of the mixture. The other leading component (11-28%) was found to be 11-n-hexadecenoic acid. Among the unsaturated acids were two diunsaturated ones, an n hexadecadienoic acid and an iso-heptadecadienoic acid. No significant differences between the fatty acid compositions of the vegetative cells and myxospores could be detected. The fatty acid composition of M. xanthus was found to be markedly similar to that of Stigmatella aurantiaca. It is suggested that a fatty acid pattern consisting of a large proportion of iso-branched C(15) and C(17) acids and a substantial amount of an n-16:1 acid is characteristic of myxobacteria. PMID- 4197904 TI - Biological activity of heated diphtheria toxin. AB - Diphtheria toxin splits into two fragments when heated at 100 C for 10 min in a phosphate buffer. The separated fragments have molecular weights of 24,000 and 39,000, respectively. These molecular weights are similar to those of the A and B fragments found in diphtheria toxin preparations after thiol reduction. Since the separation of toxin into fragments is not complete, it is likely that only nicked toxin molecules having a cleaved peptide bond are split by heating. When toxin is suspended in phosphate buffer at pH 6.4, the B-like fragment precipitates, but at pH 7.8 it does not. Heated toxin is unable to intoxicate sensitive cells or cause a necrodermal response in animals. Fragment A produced by heating is active in inhibiting cell-free protein synthesis. It is able to intoxicate both HeLa and L cells when the uptake of the fragment is facilitated by addition of polyornithine to the cultures. Fragment B produced by heating is involved with binding to the cell surface. It is able to delay the action of toxin on KB cell cultures preincubated with fragment B. PMID- 4197905 TI - Cell surface protein of Pseudomonas (Hydrogenomonas) facilis. AB - Intact cells of Pseudomonas facilis contain one major molecular weight class of protein that is exposed at the cell surface as revealed by lactoperoxidase catalyzed iodination with (125)I. All molecular weight classes of protein in derived cell envelope preparations are apparently saturated by iodination by lactoperoxidase after prolonged sonic treatment. The molecular weight of the predominantly exposed protein in intact cells is approximately 16,000, which is the minimal molecular weight of a cell envelope protein that precipitates as a complex with phospholipid from extracts of P. facilis. The isolation of labeled phospholipoprotein (PLP) after labeling intact cells with (125)I corroborates previous experiments which suggested a surface location for the protein portion of the phospholipoprotein (P(PLP)). Solvent extraction of cells and immunological evidence, including studies with ferritin-coupled antibodies, indicate that P(PLP) is located at the cell surface and may also be within the cell envelope. These experiments suggest that P(PLP) is the major cell surface protein in P. facilis. PMID- 4197906 TI - Scanning electron microscopy of colonies of six species of Candida. AB - Thirty strains of six species of Candida isolated from patients were cultured for 60 h on Sabouraud agar, freeze-dried, and examined with a scanning electron microscope. The colonies were circular (Candida albicans, C. guilliermondii) or oval (C. tropicalis, C. pseudotropicalis, C. krusei, C. parakrusei) in outline, and those of C. pseudotropicalis and C. krusei had an irregular outline due to a peripheral pseudomycelium. The morphology of individual microorganisms was examined at the margins and apex of those species which lacked a surface coat (C. pseudotropicalis, C. krusei, C. parakrusei, C. guilliermondii), and through cracks in the surface coating of those which showed a surface coat (C. albicans, C. tropicalis). All species showed buds, bud scars, and interconnecting intercellular processes, but were generally spherical (C. albicans, C. tropicalis) or ovoid (C. pseudotropicalis, C. krusei, C. parakrusei, C. guilliermondii) in fixed preparations. In unfixed material, individual organisms were almost invariably indented. Fixation with 3% glutaraldehyde and washing before freeze-drying caused partial removal of the surface coating of colonies of C. albicans and C. tropicalis, which persisted only as irregular sheets or as a filamentous meshwork. This filamentous meshwork was also present among the organisms of colonies of C. albicans, C. tropicalis, and C. pseudotropicalis. It is concluded that these filaments represent the precipitation or unmasking of some component of the intercellular matrix of these organisms. PMID- 4197907 TI - Purification of Synechococcus lividus by equilibrium centrifugation and its synchronization by differential centrifugation. AB - A culture of the thermophilic, unicellular, blue-green alga Synechococcus lividus was freed from two thermophilic bacteria by use of equilibrium (isopycnic) centrifugation in Ficoll density gradients. After removal of the bacteria, the alga would grow only on agar plates in a high carbon dioxide atmosphere. Intermittent illumination, equilibrium centrifugation, and differential centrifugation were tested as techniques for obtaining synchronized cultures of the alga. Daughter cells selected by differential centrifugation in Ficoll density gradients yielded the best synchrony, and a cross-wall index of 85% was observed during the period of cell division. PMID- 4197908 TI - Loss of photosynthetic activity in two blue-green algae as a result of osmotic stress. AB - A progressive loss of photosynthetic activity occurred when cells of Anacystis nidulans and Coccochloris peniocystis were incubated in increasing concentrations of osmotica from 0.2 to 0.7 M, and there was a release of pteridine from the cells proportional to the loss of photosynthetic activity. PMID- 4197909 TI - Agglutination of bacterial spheroplasts: agglutination-dependent degradation of Escherichia coli ribosomal ribonucleic acid. AB - When Escherichia coli spheroplasts made by ethylenediaminetetraacetic acid and lysozyme were agglutinated by concanavalin A (con A), the degradation of ribosomal ribonucleic acid (rRNA) was found to occur proportionally to the degree of the agglutination, which was determined by microscopic examination or by a newly devised assay based on the slower settling of aggregates. Methyl-alpha-d glucoside, low temperature or alkaline pH, all of which reverse the agglutination, also reduced the extent of rRNA degradation. This degradation was not due to the direct action of con A since a similar relationship was found in the case of spontaneous agglutination with concentrated spheroplasts in the absence of con A. The possible importance of a change in the cell membrane associated with the agglutination process is discussed in connection with the initiation of rRNA degradation. PMID- 4197910 TI - Fatty acid composition of L-forms of Streptococcus faecalis cultured at different osmolalities. AB - The fatty acid composition of the membranes of three different penicillin produced L-forms of Streptococcus faecalis was determined: (i) a stable (nonreverting) L-form (T(53)) cultured in brain heart infusion (BHI) with 0.5 M sucrose; (ii) a stable L-form (T(531)) cultured in BHI without sucrose; and (iii) an unstable L-form (T(9)) cultured in BHI with 0.5 M sucrose and 1,000 U of penicillin per ml. L-forms were obtained by centrifugation and lysed by washing in 1 mM tris(hydroxymethyl)aminomethane-hydrochloride buffer. The parent S. faecalis was also cultured in BHI and BHI containing 0.5 M sucrose, and washed with buffer. The fatty acid composition of L-forms of S. faecalis cultured in BHI without sucrose (370 mosmol) had higher C(18:1) and lower C(18) than L-forms cultured in the same media with added 0.5 M sucrose (950 mosmol) in both exponential and stationary cultures. In the stationary phase of growth, C(19) was reduced in the L-forms cultured without sucrose. Similar changes were seen in the parent S. faecalis cultured in the two types of media. These changes in membrane fatty acids may relate to osmo-regulation of the L-forms. PMID- 4197911 TI - Detergent-dispersed adenylate cyclase from rat brain. Effects of fluoride, cations, and chelators. PMID- 4197913 TI - Glucosamine HCl, hydroxyproline and developmental homoeostasis in Drosophila melanogaster. PMID- 4197912 TI - Dissociated learning and state-dependent retention induced by pentobarbital in rhesus monkeys. PMID- 4197914 TI - H. influenzae pneumonia in infants and children. PMID- 4197915 TI - Insulin and sodium bicarbonate treatment of diabetic acidosis: a retrospective review. PMID- 4197916 TI - Cromolyn therapy for severe asthma in children. PMID- 4197917 TI - Blood lipid alterations in infants receiving intravenous fat-free alimentation. PMID- 4197918 TI - Postexchange transfusion hepatitis in the newborn infant. PMID- 4197919 TI - Diabetes and pregnancy. PMID- 4197920 TI - Physiotherapy and the care of the progressively ill patient. 2. The unconscious and bed-ridden patient. PMID- 4197921 TI - Serological titres following vaccination of sheep and goats with Brucella melitensis rev I vaccine. PMID- 4197922 TI - A serological investigation on adult cattle vaccinated with Brucella abortus strain 19. PMID- 4197923 TI - Hyperphagia induced by intrahypothalamic implants of mercury thioglucose. PMID- 4197924 TI - Prostaglandins and food intake of rats: a component of energy balance regulation? PMID- 4197925 TI - A simple method for measuring spontaneous motor activity in squirrel monkeys during chair restraint. PMID- 4197926 TI - Effect of hemin on the synthesis of hemoglobin and other proteins in mammalian cells. AB - The initiation of globin synthesis in intact reticulocytes and in reticulocyte lysates is maintained by the addition of hemin. The specificity of this effect has been studied to determine whether it is restricted to hemoglobin and erythroid cells. In intact reticulocytes, hemin (500 muM) enhances the synthesis of carbonic anhydrase as well as of hemoglobin. Similar enhancement of protein synthesis is observed on addition of hemin (500 muM) to intact Krebs II ascites tumor cells, in cell-free extracts of these cells, added hemin (50 muM) increases endogenous protein synthesis and the translation of exogenous rabbit globin messenger RNA. These results provide evidence that the effect of hemin is not restricted to globin, and they suggest that hemin may enhance protein synthesis in at least some nonerythroid cells. PMID- 4197927 TI - Neurophysiology of flight in wild-type and a mutant Drosophila. AB - We report the flight motor output pattern in Drosophila melanogaster and the neural network responsible for it, and describe the bursting motor output pattern in a mutant. There are 26 singly-innervated muscle fibers. There are two basic firing patterns: phase progression, shown by units that receive a common input but have no cross-connections, and phase stability, in which synergic units, receiving a common input and inhibiting each other, fire in a repeating sequence. Flies carrying the mutation stripe cannot fly. Their motor output is reduced to a short duration, high-frequency burst, but the patterning within bursts shows many of the characteristics of the wild type. The mutation is restricted in its effect, as the nervous system has normal morphology by light microscopy and other behaviors of the mutant are normal. PMID- 4197928 TI - Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent. AB - The antiviral activity of the synthetic nucleoside, Virazole (1-beta-D ribofuranosyl-1,2,4-triazole-3-carboxamide), against measles virus in Vero cell cultures was substantially reversed by xanthosine, guanosine, and to a slightly lesser extent by inosine. Virazole 5'-phosphate was subsequently found to be a potent competitive inhibitor of inosine 5'-phosphate dehydrogenase (IMP:NAD(+) oxidoreductase, EC 1.2.1.14) isolated from Escherichia coli (K(m) = 1.8 x 10(-5) M) with a K(i) of 2.7 x 10(-7) M. Guanosine 5'-phosphate (GMP) was a competitive inhibitor of this enzyme with a K(i) of 7.7 x 10(-5) M. Virazole 5'-phosphate was similarly active against IMP dehydrogenase isolated from Ehrlich ascites tumor cells, with a K(i) of 2.5 x 10(-7) M. The K(m) for this enzyme was 1.8 x 10(-5) M, and the K(i) for GMP was 2.2 x 10(-4) M. These results suggest that the antiviral activity of Virazole might be due to the inhibition of GMP biosynthesis in the infected cell at the step involving the conversion of IMP to xanthosine 5' phosphate. This inhibition would consequently result in inhibition of the synthesis of vital viral nucleic acid. PMID- 4197929 TI - An RNA polymerase mutation causing temperature-sensitive sporulation in Bacillus subtilis. AB - A single-site mutant of Bacillus subtilis with a rifampin-resistant RNA polymerase has been isolated; this mutation causes temperature-sensitive sporulation. The temperature-sensitive mutation was only expressed during a limited time period, covering the middle third of the sporulation sequence. Mutant cells grown at the nonpermissive temperature exhibited the normal change in RNA polymerase template specificity, accumulated extracellular proteolytic activity and antibiotic activity, but failed to accumulate alkaline phosphatase and, hence, were blocked at or near stage III in the sporulation sequence. Pulse labeled RNA synthesis was seriously deranged during postexponential growth phase in mutant cells incubated at the nonpermissive temperature. PMID- 4197930 TI - Inhibition of cellular protein synthesis by double-stranded RNA: inactivation of an initiation factor. AB - Inhibition of protein synthesis in rabbit reticulocyte lysates by double-stranded RNA is caused by the inactivation of IF-3, an initiation factor required for the recycling of ribosomes and for their binding to messenger RNA. The evidence for this is that (i) the inhibition can be overcome by addition of exogenous If-3; (ii) double-stranded RNA inactivates stoichiometric amounts of IF-3; (iii) double stranded RNA forms a complex with IF-3; and (iv) double-stranded DNA, which lacks inhibitory activity, also binds to IF-3, but with a much lower affinity than double-stranded RNA. It is concluded that double-stranded RNA inhibits cellular protein synthesis by tightly complexing with IF-3. It is suggested that IF-3 normally recognizes a double-stranded region in messenger RNA. PMID- 4197931 TI - Magnetic dipole-dipole coupled Cu(II) pairs in nitric oxide-treated tyrosinase: a structural relationship between the active sites of tyrosinase and hemocyanin. AB - The T(r) and T[unk] states of tyrosinase were treated with NO. EPR spectra of the products observed at 14 degrees K and at 113 degrees K showed mixtures of two signals. One had components in the region of g = 2, about 1200 G wide, and in the region of g = 4, showing hyperfine splitting. The other signal was similar to that arising from isolated Cu(II) ions in an axially symmetric environment. The first signal was indicative of Deltam = 1 and Deltam = 2 transitions arising from magnetic dipole-dipole coupled Cu(II) ion pairs. It closely resembled previously reported EPR spectra obtained from NO-treated hemocyanin, which were confirmed in this study. The normal Curie behavior of the signals between 230 degrees K and 14 degrees K ruled out significant exchange coupling between the ion pairs. The Deltam = 2 signals were not saturable up to 350 mW at 14 degrees K. The broad Deltam = 1 signals could be separated from accompanying signals by the saturation characteristics of the latter at about 10 mW at 14 degrees K. The results establish the presence of a pair of copper ions at the active site of tyrosinase, and a clsoe structural relationship between this active site and that of hemocyanin. PMID- 4197932 TI - Epilepsy after non-missile head injuries. PMID- 4197933 TI - Stroma-free hemoglobin. I. Preparation and observations on in vitro changes in coagulation. PMID- 4197934 TI - Altered insulin and glucose metabolism produced by epinephrine during hemorrhagic shock in the adrenalectomized primate. PMID- 4197935 TI - The effect of hemorrhagic shock on intracellular muscle action potentials in the primate. PMID- 4197936 TI - [Effect of formaldehyde and beta-propiolactone on the infectivity and antigenicity of the causative agent of viral gastroenteritis of swing (VGS)]. PMID- 4197937 TI - [Phthalylsulfathiazol in the prevention and therapy of diarrhea in newborn calves]. PMID- 4197938 TI - [Diagnostic importance of the determination o f bull's sperm movement rate by photogrammetric method and by propulsivity test]. PMID- 4197939 TI - [Exhalations at the East-Slovakian ironworks and their effects on the sheep and cattle in animal experiments]. PMID- 4197940 TI - [Possibilities in the use of ultrasound for the preparation of the precipitation antigen of Newcastle disease virus]. PMID- 4197941 TI - A brief note on the chemical nature of the precipitate within nerve fibers after the rapid Golgi reaction: selected area diffraction in high voltage electron microscopy. PMID- 4197942 TI - Architectonic parcellation of the temporal operculum in rhesus monkey and its projection pattern. PMID- 4197943 TI - [ -Motor nerve fibres. The crossectional area of stem fibre and terminal branches]. PMID- 4197944 TI - [Activity of methionine synthetase (5-methyl-5,6,7,8-tetrahydrofolate: homocysteine methyltransferase) as a proliferation parameter in growing cells]. PMID- 4197945 TI - -aminolaevulinic acid synthetase activity in normal human liver homogenate. PMID- 4197947 TI - Serum B 12 binders in vitamin B 12 deficiency. Relation of serum B 12 and haemoglobin levels with B 12 binders. PMID- 4197946 TI - Factors influencing splenic pooling of erythrocytes in the myelo- and lympho proliferative syndromes. PMID- 4197948 TI - Effect of corticosteroids on eosinophil leukocytes in hypereosinophilic syndromes. PMID- 4197949 TI - Haematological effects of chronic ethanol administration and folic acid deficiency in mice. PMID- 4197950 TI - Adult human adipose tissue cellularity and metabolism with special reference to obesity and fatty acid synthesis de novo. PMID- 4197951 TI - Calciun-sensitive site in the carotid trunk at the thyroid artery issue, influencing the respiratory centre. PMID- 4197952 TI - Tumor-like lesion of the brain caused by Trypanosoma cruzi. PMID- 4197953 TI - Some epidemiological considerations of scrub typhus (Rickettsia tsutsugamushi) in a natural focus in the Zambales Mountains, Luzon, Republic of the Philippines. PMID- 4197954 TI - Annually recurrent epidemic polyarthritis and Ross river virus activity in a coastal area of new New South Wales. I. Occurrence of the disease. PMID- 4197955 TI - Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma. PMID- 4197956 TI - Systemic factors and epileptic brain damage. Prolonged seizures in paralyzed, artificially ventilated baboons. PMID- 4197957 TI - Size dependent separation of high molecular weight double-stranded DNA by means of gel electrophoresis. PMID- 4197958 TI - Dynamic aspects of membrane-bound DNA in Bacillus subtilis during the course of synchronous growth. PMID- 4197959 TI - Amino acid sequence of human erythrocyte carbonic anhydrase C. PMID- 4197960 TI - Energy-linked swelling of EDTA submitochondrial particles. PMID- 4197961 TI - Induction of biohydrogenation of oleic acid in Bacillus cereus by increase in temperature. PMID- 4197962 TI - Molecular organization in bacterial cell membranes. II. Reevaluation and identification of some chemical components of Micrococcus lysodeikticus membranes. PMID- 4197963 TI - Euglycemic diabetic ketoacidosis. PMID- 4197964 TI - Monkeys for research. PMID- 4197965 TI - [Immunological problems of sterility]. PMID- 4197966 TI - [Feto-maternal hemorrhage in the I. trimester and after interruption (curettage)]. PMID- 4197967 TI - [Hemolytic disease of the newborn during isoimmunization of the mother by anti-c antibodies]. PMID- 4197968 TI - Circulating immune complexes in inflammatory bowel disease. PMID- 4197969 TI - Morphological observations on the contact-induced lysis of target cells. PMID- 4197970 TI - Macrophage cytotoxicity factor. A product of in vitro sensitized thymus-dependent cells. PMID- 4197971 TI - Rosette formation by human T and B lymphocytes. PMID- 4197972 TI - Plasmodium berghei: folic acid levels in mouse erythrocytes. PMID- 4197973 TI - Plasmodium falciparum and P. knowlesi: low temperature preservation using dimethylsulfoxide. PMID- 4197974 TI - Studies in myasthenia gravis. Heat stability and species specificity of active muscle antigens. PMID- 4197975 TI - Role of anaerobic coryneforms in specific and non-specific immunological reactions. II. Production of a chemotactic factor specific for macrophages. PMID- 4197976 TI - Scoliosis and neurological disease. PMID- 4197977 TI - Cross reactions between the antigen of human lymphatic tissues and antigens of monkey, cow, mouse and hamster tissues. PMID- 4197978 TI - A direct turbidimetric assay of pyocine. PMID- 4197979 TI - The influence of sporulation and germination media on the development of spores of Bacillus megaterium and their inhibition by chlorocresol. PMID- 4197980 TI - Some aspects of the mode of action of the antibacterial compound bronopol (2 bromo-2-nitropropan-1,3-diol). PMID- 4197981 TI - Immunochemical analysis of chick phosvitin. PMID- 4197982 TI - Pulmonary host defenses. I. Analysis of protein and lipids in bronchial secretions and antibody responses after vaccination with pseudomonas aeruginosa. PMID- 4197983 TI - Pulmonary host defenses. II. Interaction of respiratory antibodies with Pseudomonas aeruginosa and alveolar macrophages. PMID- 4197984 TI - Protection against enteric bacterial infection by secretory IgA antibodies. PMID- 4197985 TI - Immunologic studies on drug addiction. I. Antibodies reactive with methadone and their use for detection of the drug. PMID- 4197986 TI - A latex agglutination test for measuring antibodies to Streptococcal mucopeptides. PMID- 4197987 TI - Application of electroimmunodiffusion and crossed electroimmunodiffusion to the comparative serology of a microorganism (Histoplasma capsulatum). PMID- 4197988 TI - Immunogenicity and arthritogenicity in the rat of an antigen from Mycobacterium tuberculosis wax D. PMID- 4197989 TI - Radioimmunologic measurements of naturally occurring bacterial antibodies. I. Human serum antibodies reactive with Escherichia coli in gastrointestinal and immunologic disorders. PMID- 4197990 TI - Measurement of the third component of complement in cerebrospinal fluid by modified electroimmunodiffusion. PMID- 4197991 TI - IgG, IgA, and IgM cold-reactive immunoglobulins in 19 patients with elevated cold agglutinins. PMID- 4197992 TI - Lymphocyte function in normal people with persistent Australia antigen. PMID- 4197993 TI - Isolated in vivo perfusion of the baboon brain with uncomplicated survival: a new experimental model. PMID- 4197994 TI - Cisternography: from early tribulations to a useful diagnostic procedure. PMID- 4197995 TI - The mode of action of Sterinol on microorganisms: effect on the external layers of bacterial cells. PMID- 4197996 TI - An automated method for microbiological assays. PMID- 4197997 TI - Observations on Listeria monocytogenes type 5 (Iwanow) isolated in New Zealand. PMID- 4197998 TI - [Ultrastructural study of "Australia" antigen. 1. Morphological diversity of Australia antigen]. PMID- 4197999 TI - [Inhibitors of ribonucleases]. PMID- 4198001 TI - Lectins in precipitin reactions with soluble H substance of human saliva and serum. AB - Lectins that precipitate the soluble H substances of saliva were produced for the first time from the four commonly used sources of seed. In Ouchterlony precipitin reactions, identity was observed between extracts of Cytisus sessilifolius and Laburnum alpinum, but these extracts displayed incomplete identity with extracts from Ulex europaeus. These three sources of the precipitating lectin formed bands when tested with saliva from all secretors and none with saliva from nonsecretors. Extracts from Lotus tetragonolobus, however, formed two bands with saliva from secretors and one strong band with all saliva from nonsecretors. This new antigen, which reacts with Lotus, is present in all saliva and on red cells of all normal individuals, but it is absent in the O(h) (Bombay) type. The lectins formed bands with serums of secretor and nonsecretor individuals, but these bands were weaker than those with saliva, and revealed incomplete identity between H substance of serum and saliva. The precipitin reaction of the lectins is an efficient method for demonstrating relations among lectins and among antigens and has led to the discovery of a new human antigen. PMID- 4198000 TI - Three new fragments, F(ab) 2 , F(c) 2 , and Fab-c, obtained by papain proteolysis of normal human IgG. PMID- 4198002 TI - The picornaviruses of epidemic conjunctivitis. PMID- 4198003 TI - Coagulation and fibrinolysis in simian Plasmodium knowlesi malaria. PMID- 4198004 TI - Studies on the phagocytic activity of the reticuloendothelial system using 131 I AA in normal monkeys. PMID- 4198005 TI - [Carcinoma of the rectum]. PMID- 4198006 TI - [Distribution characteristics of certain pesticides in liver lipid fractions]. PMID- 4198008 TI - Early stages of synaptogenesis in the cervical spinal cord of the chick embryo. PMID- 4198007 TI - [Antimicrobial properties of cranberry]. PMID- 4198009 TI - The morphology of the juxtaglomerular apparatus in the toad, Bufo bufo. A light microscopic study. PMID- 4198010 TI - Perforation of a jejunal diverticulum containing a lymphosarcoma and accompanied by upper gastrointestinal hemorrhage. Report of a case. PMID- 4198011 TI - A survey of 99 surgical patients treated with gentamycin. PMID- 4198012 TI - [Mechanism of the immunological adjuvant effect of vaccinia-virus]. PMID- 4198013 TI - Foamy virus serotypes 1 and 2 in rhesus monkey tissues. PMID- 4198014 TI - Bovine ephemeral fever virus in cell culture and mice. PMID- 4198015 TI - Gold nephropathy. An immunopathologic study. PMID- 4198016 TI - Factors affecting the response of microsomal UDP-glucuronyltransferase to membrane perturbants. PMID- 4198017 TI - Characteristics of H + and NH 4 + excretion by the urinary bladder of the toad. PMID- 4198018 TI - On the nature of the mid-oseophageal diverticulum. PMID- 4198019 TI - [Neurofibromatosis of the bladder]. PMID- 4198020 TI - Non-autonomy of hormone secretion in primary hyperparathyroidism. PMID- 4198021 TI - Neoplastic changes in the rat liver induced by polychlorinated biphenyl. PMID- 4198022 TI - Carriers of hepatitis B antigen: an epidemiologic and histologic study. PMID- 4198023 TI - Evaluation of the vaginal tampon as a means of obtaining cultures for Neisseria gonorrhoeae. PMID- 4198024 TI - Studies on the pathogenesis of dengue infection in monkeys. II. Clinical laboratory responses to heterologous infection. PMID- 4198025 TI - Studies on the pathogenesis of dengue infection in monkeys. 3. Sequential distribution of virus in primary and heterologous infections. PMID- 4198026 TI - Antigenicity of a polysaccharide vaccine from Neisseria meningitidis administered intranasally. PMID- 4198027 TI - Studies on the pathogenesis of dengue infection in monkeys. I. Clinical laboratory responses to primary infection. PMID- 4198029 TI - Nitrones. 6. -(5-Nitroimidazol-2-yl)-N-substituted nitrones. PMID- 4198028 TI - Potent anti-inflammatory N-heterocyclic 3-carboxamides of 4-hydroxy-2-methyl-2H 1,2-benzothiazine 1,1-dioxide. PMID- 4198030 TI - Selection of a fast-growing Chikungunya virus by passage from suckling mouse brain to VERO cells. PMID- 4198032 TI - Contamination of methylmethacrylate bone cements. PMID- 4198031 TI - Toxicogenic potentials of biomaterials and methods for evaluating toxicity. PMID- 4198033 TI - The use of a balloon catheter in the induction of labour. PMID- 4198034 TI - Diseases of the alimentary tract and western diets. PMID- 4198035 TI - [Penicillin V and drug interactions]. PMID- 4198036 TI - [Esophageal diverticulum in a cow]. PMID- 4198037 TI - [Catecholamine metabolism in the hormonal and mediator links of the sympathoadrenal system under stress]. PMID- 4198038 TI - [Orbital and temporal electropulsography in the diagnosis of the initial form of vascular atherosclerosis of the brain]. PMID- 4198039 TI - [Structural organization of the hippocampus in the prenatal ontogenesis of the lower monkeys]. PMID- 4198040 TI - Structure and connections of the rhesus vestibular cortex. PMID- 4198041 TI - Oculomotor deficiency after cerebellar cortical lesions. PMID- 4198042 TI - Ultrastructure of the otolithic membrane and the cupula. A scanning electron microscopic observation. PMID- 4198043 TI - Prebiotic evolution of enzyme-like systems. PMID- 4198045 TI - [Embryogenetic disorders in autosomal trisomy arising in the progeny of mice with Robertsonian translocation (centric fusion) T-1 IEM]. PMID- 4198044 TI - Netherlands Society for Microbiology meeting at Delft on 25 October 1972. Mycotoxins. PMID- 4198046 TI - [Morphology and pathogenesis of adjuvant polyarthritis in rats]. PMID- 4198047 TI - The ultrastructure of the blood vessels of the human dental pulp following injury. IV. PMID- 4198048 TI - Serum immunoglobulin conten in normal and lymphoid tumor-bearing Xenopus laevis. PMID- 4198049 TI - The frequency of other handicaps in children with cerebral palsy. PMID- 4198050 TI - The influence of antibovine alpha-crystallin on the development of the rabbit eye. PMID- 4198051 TI - Integumental distribution of tyrosinase activity in the slow loris, Nycticebus coucang, and the presence of integumental tyrosinase inhibitor(s). PMID- 4198052 TI - Asymmetrical responses to direction selection for radiation resistance and sensitivity in Drosophila. PMID- 4198053 TI - The topography of the premaxillary-frontal region in nonhuman primates. PMID- 4198054 TI - An X-O anomaly and ovarian dysgenesis in a rhesus monkey. PMID- 4198055 TI - Chromosomal evolution in a rhesus cell line. PMID- 4198056 TI - Social behavior comparison in laboratory-reared stumptail and rhesus macaques. PMID- 4198057 TI - The reproductive cycles of two subspecies of purple-faced langurs (Presbytic senex) with relation to environmental factors. PMID- 4198058 TI - Homosexual behavior and dominance hierarchy in a group of captive female squirrel monkeys (Saimiri sciureus). PMID- 4198059 TI - Chloroplast membrane proteins. II. Solubilization of the lipophilic components. PMID- 4198060 TI - Subunit structure of fragment D from fibrinogen and cross-linked fibrin. PMID- 4198061 TI - Polymorphism of rhesus monkey serum prealbumin. Molecular properties and binding of thyroxine and retinol-binding protein. PMID- 4198062 TI - Mammary tumor regression. V. Role of acid ribonuclease and cathepsin. PMID- 4198063 TI - Mammary tumor regression. VI. Synthesis and degradation of acid ribonuclease. PMID- 4198064 TI - Purification and comparison of sex-dependent and sex-independent gulonolactonase of rats. PMID- 4198065 TI - The relationship of serine protease activity to RNA polymerase modification and sporulation in Bacillus subtilis. PMID- 4198066 TI - Basal study on early diagnosis of cadmium poisoning: change in carbonic anhydrase activity. PMID- 4198067 TI - Serum immunoglobulins and coproantibody formation in infants after artificial intestinal colonization with Escherichia coli 083 and oral lysozyme administration. PMID- 4198068 TI - [Human placentar lactogen (HPL) in the serum of pregnant women with diabetes, Rh incompatibility, severe toxemia and twins]. PMID- 4198069 TI - [Human placental lactogen in endangered pregnancy]. PMID- 4198070 TI - [Results of placental circulation measurements in hazard pregnancies]. PMID- 4198071 TI - The biology of human aging. PMID- 4198072 TI - [A case of post-traumatic acromegaly]. PMID- 4198073 TI - [Effects of TSH releasing factor (TRH) and LH releasing factor (LH-RH) in hypopituitarism]. PMID- 4198074 TI - Studies on human thyroxine-binding globulin. 8. Isoelectric focusing evidence for microheterogeneity of thyroxine-binding globulin. PMID- 4198075 TI - Purification and properties of rat adrenal phenylethanolamine-N-methyl transferase. PMID- 4198076 TI - Studies on the immunological cross-reactivity and physical properties of fatty acid synthetases. PMID- 4198077 TI - Effect of secondary interaction on the enzymatic activity of trypsin-like enzymes from Streptomyces. PMID- 4198078 TI - [Isolation of M and N antigens from dried blood stains]. PMID- 4198080 TI - Solitary mastocytoma. PMID- 4198079 TI - Intestinal malabsorption in malnourished children and during recovery. Duodenal contents of lipase, nitrogen, and micellar fat after fat stimulation. PMID- 4198081 TI - The bacterial degradation of flavonoids. Oxidative fission of the A-ring of dihydrogossypetin by a Pseudomonas sp. AB - Cell-free extracts prepared from a Pseudomonas sp., grown on (+)-catechin, oxidized dihydrogossypetin (3',4',5,7,8-pentahydroxyflavanonol) by cleaving the A ring to form oxaloacetic acid from C-5, C-6, C-7 and C-8 together with 5-(3,4 dihydroxyphenyl)-4-hydroxy-3-oxovalero-delta-lactone. The structure of this lactone was confirmed by synthesis of related phenylvalerolactones. PMID- 4198082 TI - Sporulation in Bacillus subtilis. Properties and time of synthesis of alkali soluble protein of the spore coat. AB - An alkali-extractable protein fraction comprising 6% of the dry weight of the spore can be removed from spores of Bacillus subtilis 168. Three different extraction procedures each yield at least one similar protein. Extracted protein behaved as a single species on ion-exchange chromatography or gel filtration, but two polypeptides were found on electrophoresis. Comparison of molecular weights on electrophoresis and by sucrosegradient analysis suggests that the protein(s) undergo aggregation into multimers. Extracted spores remain viable, but are altered in density and lysozyme sensitivity and they aggregate together. Electron microscopy of extracted spores shows that loss of material seems to occur from the outer coat layers. Extraction therefore probably removes a specific fraction of the spore-coat protein, but without impairment to the spore protoplast. This protein can first be detected immunologically 4h after the initiation of sporulation, and the synthesis of this protein is sensitive to chloramphenicol, actinomycin D and rifamycin. Labelling experiments also show that the protein begins to be synthesized early in sporulation. Examination of the ability of asporogenous mutants to produce cross-reacting material indicates that some event in stage II of sporulation determines its production. PMID- 4198083 TI - The uptake and metabolism of plasma lysophosphatidylcholine in vivo by the brain of squirrel monkeys. AB - 1. Adult squirrel monkeys were injected intravenously with doubly labelled lysophosphatidylcholine (a mixture of 1-[1-(14)C]palmitoyl-sn-glycero-3 phosphorylcholine and 1-acyl-sn-glycero-3-phosphoryl[Me-(3)H]choline; (3)H:(14)Cratio 3.75) complexed to albumin, and the incorporation into the brain was studied at times up to 3h. 2. After 20min, 1% of the radioactivity injected as lysophosphatidylcholine had been taken up by the brain. 3. Approx. 70% of the doubly labelled lysophosphatidylcholine taken up by both grey and white matter was converted into phosphatidylcholine, whereas about 30% was hydrolysed. 4. The absence of significant radioactivity in the phosphatidylcholine, free fatty acid and water-soluble fractions of plasma up to 30min after injection of doubly labelled lysophosphatidylcholine rules out the possibility that the rapid labelling of these compounds in brain could be due to uptake from or exchange with their counterparts in plasma. 5. The similarity between the (3)H:(14)C ratios of brain phosphatidylcholine and injected lysophosphatidylcholine demonstrates that formation of the former occurred predominantly via direct acylation. 6. Analysis of the water-soluble products from lysophosphatidylcholine catabolism revealed that appreciable glycerophosphoryl-[Me-(3)H]choline did not accumulate in the brain and that radioactivity was incorporated into choline, acetylcholine, phosphorylcholine and betaine. 7. The role of plasma lysophosphatidylcholine as both a precursor of brain phosphatidylcholine and a source of free choline for the brain is discussed. PMID- 4198084 TI - Stimulatin of tryptophan metabolism in the rat by 4-dimethylamino 3'methylazobenzene and 2-acetamidofluorene. PMID- 4198085 TI - Possible role of a thiol group in lactose synthetase A protein. PMID- 4198086 TI - Effect of inducers on the metabolism and excretion of disodium cromoglycate in rats. PMID- 4198087 TI - Hepatic and extrahepatic reduction of nicotine 1'-N-oxide in rats. PMID- 4198088 TI - Asparagine transport in Lactobacillus plantarum and Streptococcus faecalis. PMID- 4198089 TI - Potentiation and modulation of the immune response of guinea pigs to poorly immunogenic protein-hapten conjugates by pretreatment with the MER fraction of attenuated tubercle bacilli. PMID- 4198090 TI - [Therapeutic approach in toxicoseptic shock]. PMID- 4198091 TI - [Collapse of vertebral bodies in dialysis osteopathy]. PMID- 4198092 TI - [Condylar growth in the light of new experimental research results--a literature survey]. PMID- 4198093 TI - Estimates and estimation errors of hormone secretion, transport and disposal rates in the maternal-fetal system. PMID- 4198094 TI - Development of cortisol binding in the rhesus monkey. PMID- 4198095 TI - An analysis of the negative feedback control of gonadotropin secretion utilizing chronic implantation of ovarian steroids in ovariectomized rhesus monkeys. PMID- 4198096 TI - Effect of synthetic TRF on prolactin release in the sheep. PMID- 4198097 TI - Risks, research, and reason. PMID- 4198098 TI - Pancreatic biogenic amines and insulin secretion in health and disease. PMID- 4198099 TI - Erythrocebus patas--an anatomically suitable primate model for reproductive studies. PMID- 4198100 TI - Altered immune function in hypercholesterolemic monkeys. AB - Humoral and cellular immune responses to several antigens were compared in control and hypercholesterolemic groups of monkeys. Chronic hypercholesterolemia, with concomitant hyperphospholipidemia and hypotriglyceridemia, was produced experimentally by feeding monkeys a high-fat, high-cholesterol diet. When studied prior to infection, hypercholesterolemic monkeys exhibited impaired development of precipitating antibodies against ovalbumin, enhanced sensitivity to tuberculin antigen (stimulated apparently by mycobacterial components in complete Freund adjuvant), and an increased rate of clearance of colloidal carbon from blood. During pneumococcal infection the ability of neutrophiles from hypercholesterolemic monkeys to reduce nitroblue tetrazolium dye showed an increase greater than that of control monkeys; both groups exhibited increased but comparable final clearance rates of colloidal carbon, although the increment of increase was smaller in hypercholesterolemic monkeys. PMID- 4198101 TI - Extracellular factor synthesized by Bacillus cereus which evokes a dermal reaction in guinea pigs. AB - A guinea pig skin assay was developed as a measure of ileal loop fluid-inducing factor in the rabbit and possibly of the causative principle of Bacillus cereus food poisoning. A green or bloody necrotic reaction was produced in the guinea pig skin by injection of culture filtrates from 21 of 24 B. cereus strains tested, and by no other Bacillus species tested except for the closely related B. thuringiensis. The skin factor was synthesized and excreted by logarithmically growing cells, inactivated by heating at 56 C for 5 min, precipitable by ammonium sulfate, and was nondialyzable. The skin activity was not related to the lecithinolytic or hemolytic activities of B. cereus. Production of the skin factor depended on the medium in which the culture was growing. The factor was an antigenically active substance. There are indications that at least two antigenically distinct species of skin factors exist. PMID- 4198102 TI - Effect of colon flora and short-chain fatty acids on growth in vitro of Pseudomonas aeruginsoa and Enterobacteriaceae. AB - Heat-stable antibacterial activity in the following suspensions was demonstrated against Pseudomonas aeruginosa at pH 6.5, 6.0, and 5.5: (i) pooled colon contents of normal mice; (ii) an anaerobic, 48-h culture of normal mouse feces; and (iii) anaerobic, 48-h cultures of different bacteria from human colon flora (Escherichia coli, Bacteroides fragilis, Klebsiella pneumoniae, and Proteus mirabilis). The lower the pH of the medium, the greater was the antibacterial activity of these suspensions. The antibacterial activity of five fatty acids (propionic, butyric, isobutyric, acetic, and formic acids) was greater against P. aeruginosa than against three Enterobacteriaceae (E. coli, K. pneumoniae, and P. mirabilis) at all fatty acid concentrations (0.16 M to 0.005 M) and at the 3 pH values studied (5.5, 6.0, and 6.5). As the pH value increased, the antibacterial activity decreased. Antibacterial activity was greater at higher fatty acid concentrations, and at each pH value it was greatest for the fatty acids having high pK(a) values. Lactic acid, with the lowest pK(a), exhibited little or no antibacterial activity. Acetic and butyric acids, two of the three predominant volatile fatty acids determined by gas chromatography in the mouse colon contents and in the anaerobic culture of mouse feces, occurred in vivo in concentrations which inhibited growth of P. aeruginosa in vitro at the pH of the mouse cecum. These results suggest that undissociated short-chain fatty acids produced by the colon flora may be a mechanism of intestinal resistance to colonization by P. aeruginosa. PMID- 4198103 TI - Relationship between tuberculin hypersensitivity and cellular immunity to infection in mice vaccinated with viable attenuated Mycobacterial cells or with Mycobacterial ribonucleic acid preparations. AB - The migration inhibition technique has been used to study delayed hypersensitivity in vitro by using peritoneal exudate cells and splenic lymphocytes from mice vaccinated with viable cells of the attenuated H37Ra strain of Mycobacterium tuberculosis and from mice vaccinated with ribonucleic acid (myc RNA) preparations obtained from viable mycobacterial cells of the same strain. Inhibition of macrophage migration was noted when purified protein derivative (PPD) or viable H37Ra cells were added to peritoneal exudate cells obtained from mice immunized with viable H37Ra cells and not from mice immunized with myc RNA. Splenic lymphocyte cultures were exposed to the same antigens in vitro. Filtered supernatant fluids from these lymphocyte cultures, when added to peritoneal exudate cells obtained from nonimmunized mice, inhibited migration only when they were obtained from lymphocytes which came from mice immunized with viable H37Ra cells. Injection of PPD intravenously into vaccinated mice resulted in inhibitory supernatant fluids from splenic lymphocyte cultures only when the lymphocytes came from mice immunized with viable H37Ra cells. However, intravenous injection of either viable H37Ra cells or of myc RNA preparations into mice vaccinated with myc RNA occasionally produced inhibitory supernatant fluids when lymphocytes were obtained from these mice. On the other hand, mice vaccinated with myc RNA or viable H37Ra cell preparations were consistently and equally protected against intravenous challenge with the virulent H37Rv strain. Thus, although some evidence was obtained for a delayed type hypersensitivity in mice vaccinated with H37Ra cells or with myc RNA to ribosomal proteins or other proteins associated with the RNA preparation, no evidence of tuberculin hypersensitivity could be detected in any mice vaccinated with the myc RNA. These results argue against a role for tuberculin hypersensitivity in immunity to tuberculous infection. PMID- 4198104 TI - Metabolism of Richettsia tsutsugamushi and Rickettsia rickettsi in irradiated host cells. AB - The metabolism of Rickettsia tsutsugamushi (Gilliam strain) multiplying in irradiated L cells was investigated by methods involving the use of (14)C-labeled substrates and cycloheximide, an inhibitor of eukaryotic metabolism. Cycloheximide-resistant amino acid and adenine incorporations were appreciably higher in infected than in uninfected cultures during the period from 3 to 5 or 6 days postinoculation. The metabolism of R. rickettsi was similarly studied in primary duck embryo cells, which are more susceptible to infection with this rickettsia than are L cells. A difference in cycloheximide-resistant activity between infected and uninfected cultures was also noted, but was small. This finding is attributed to the more limited growth of R. rickettsi. PMID- 4198105 TI - Interaction of gonococci with phagocytic leukocytes from men and mice. AB - The interaction of human and mouse phagocytic leukocytes with representative virulent (F62-T1) and avirulent (F62-T4, RD-5) strains of Neisseria gonorrhoeae was studied in vitro. Leukocyte monolayers were incubated with gonococci for 30 min at 37 C, washed repeatedly, reincubated with fresh medium, and sampled for viable bacteria at intervals. After the initial incubation period and washing, human leukocytes retained larger numbers of viable T1 than of T4. During the subsequent 120 min of incubation, the numbers of viable T1 remained approximately constant, whereas viable counts of T4 declined by about two-thirds. In contrast, mouse leukocytes under similar conditions destroyed 70% of both types of gonococci. When human bactericidal serum was applied to infected human leukocytes, it had no effect on T4 but inactivated over 50% of T1. It is concluded that T4 are phagocytized by human leukocytes and are thus exposed to internal digestion, but are protected from bactericidal serum. T1, on the other hand, either adhere to the surface of the leukocytes or remain located so that they are neither digested by the leukocytes nor protected from bactericidal serum. PMID- 4198106 TI - Free fatty acid content of cacao beans infested with storage fungi. PMID- 4198107 TI - Metabolism and excretion of exogenous thyrotropin-releasing hormone in humans. AB - To study the metabolism of thyrotropin-releasing hormone (TRH) in vivo, 400 mug TRH was administered intravenously to eight normal male subjects. Multiple plasma and urine samples were obtained before and after TRH administration. Serum TSH concentrations increased after TRH administration in all subjects. Plasma TRH levels, measured by radioimmunoassay, were undetectable (< 0.4 ng/ml) before TRH administration. Plasma TRH concentrations averaged 33+/-7 ng/ml (mean +/-SEM) 2 min after TRH injection. Thereafter, they decreased rapidly so that the mean plasma TRH level was 2.9 ng/ml 20 min after TRH administration. The fall in plasma TRH levels was linear during this interval. Thereafter TRH levels declined more slowly. The mean half-life (t(1/2)) of TRH was 5.3+/-0.5 min. The mean distribution volume was 15.7+/-3.8 liters, an average of 16.5% of body weight in these subjects. In the urine, 5.5+/-0.9% of the administered TRH was recovered in the 3 h after TRH administration. Of the total urinary TRH recovered, 84.9% was excreted in the first 30 min. These results indicate that TRH is distributed in a large volume, that it is rapidly metabolized and that a significant quantity of administered TRH is excreted in the urine. PMID- 4198108 TI - Endocrine studies in anencephaly. AB - Endocrine function has been investigated in four anencephalic neonates to determine the influence of absence of cortical and hypothalamic tissue and of hypoplasia of the pituitary. Intravenous glucose administration resulted in higher peak values for blood sugar and more rapid glucose disposal rates than reported in normals. Intravenous insulin tolerance tests on two of the infants failed to evoke elevations in plasma growth hormone, and the infants showed a remarkable resistance to the hypoglycemic effect of insulin. Administration of lysine-vasopressin caused an active growth hormone release. Similarly, there was a large increase in serum thyrotropin after administration of synthetic thyrotropin-releasing hormone. Basal levels of both thyrotropin and growth hormone were low as compared with values reported for normal newborns. Prolactin values obtained on three of the infants were in the normal range. The results strongly suggest that anterior pituitary function mediated by the hypothalamus and its releasing factors is deficient in anencephaly. However, the anterior pituitary can release growth hormone and thyrotropin when stimulated directly and, in the case of thyrotropin release, may function autonomously. The normal prolactin values presumably reflect the absence of the hypothalamic prolactin inhibitory factor. PMID- 4198109 TI - The association of respiratory infection, recurrent hematuria, and focal glomerulonephritis with activation of the complement system in the cold. AB - The study of the activation of C3, C5, and C7 associated with the conversion of C3 in the serum of a 9-yr old girl after incubation at 0 degrees C for 6-8 h without utilization of C1, C4, and C2 is described. The patient has upper respiratory infections associated with recurrent gross hematuria, focal glomerulonephritis, and transient renal insufficiency. Histological lesions demonstrated the presence of B1c globulin IgA and properdin in the glomeruli. The activation of complement (C) in the cold requires the patient's IgA. Removal of IgA from the serum by immunoadsorption prevents activation and conversion of C3. Bactericidal and phagocytic activity is also impaired after incubation. C3 proactivator (C3PA) level is reduced before and after incubation. Properdin level drops after incubation. These findings suggest that the activation of C3 which is demonstrable in vitro may be a continuous process in vivo. PMID- 4198110 TI - Isolation of Neisseria lactamicus from the nasopharynx. AB - During 1971 and 1972, 71 cultures of neisseriae that attacked lactose were received by this laboratory. All strains except one from an eye swab were from the nasopharynx of healthy subjects. Nineteen similar strains from the nasopharynx were isolated in this laboratory. The characteristics of these strains were compared with those of Neisseria meningitidis, Neisseria pharyngis, Neisseria catarrhalis, and Neisseria lactamicus. The 90 strains under investigation closely resembled Neisseria meningitidis but could be differentiated by production of acid from lactose and beta-galactosidase activity and were therefore classified as Neisseria lactamicus. PMID- 4198111 TI - Cross immunity studies with East and West African strains of Plasmodium falciparum in owl monkeys (Aotus trivirgatus). PMID- 4198112 TI - Evaluation of the complement fixation test in diagnosis of actinomycetoma. PMID- 4198113 TI - Autoantibodies in schistosomal liver fibrosis. PMID- 4198114 TI - Neonatal gonococcal infection. I. Orogastric contamination with Neisseria gonorrhoea. PMID- 4198115 TI - Altered enzyme molecules in senescent organisms: mouse muscle aldolase. PMID- 4198116 TI - Effect of MDMP on protein synthesis in wheat and bacteria. PMID- 4198117 TI - [Studies on the isolation and elucidation of constitution of the rhyodomycin antibiotic agent in the streptomyces strain JA 8467]. PMID- 4198118 TI - [Fungistatic effect of ranunculaceae species]. PMID- 4198119 TI - The role of nutrition in the physiological and behavioral effects of early maternal separation on infant rats. PMID- 4198120 TI - Electrocardiographic and cardiac morphological changes associated with environmental stress in squirrel monkeys. PMID- 4198121 TI - An angiographic study of the meningorachidian venous system. PMID- 4198122 TI - Simple measurement of chest-wall thickness with ultrasound. PMID- 4198123 TI - Reemphasis on tuberculosis. PMID- 4198124 TI - Accommodative vergence in the alert monkey. Motor unit analysis. PMID- 4198125 TI - Early malnutrition and brain development. PMID- 4198126 TI - [Carbenicillin treatment of Pseudomonas aeruginosa infections and Proteus infections in infants]. PMID- 4198127 TI - The neurocranial basis for facial form and pattern. PMID- 4198128 TI - Environmental factors internal to the host that affect the sucess of microbial insecticides. PMID- 4198129 TI - Effects of entomopathogens on vertebrates. PMID- 4198130 TI - Environmental impact of insect control by microorganisms. PMID- 4198132 TI - Perspectives of biological insect control. PMID- 4198131 TI - Enzootic diseases of insects. PMID- 4198133 TI - Means for insect regulation. Microbial toxins. PMID- 4198134 TI - Determination of the molecular weight in nucleic acids by end-phosphate analysis. PMID- 4198135 TI - Properties of oligodeoxynucleotides that determine priming activity with Escherichia coli deoxyribonucleic acid polymerase I. PMID- 4198136 TI - Electron microscopy of Bacillus subtilis protoplast membrane after treatment with phospholipase A 2 and phospholipase C. PMID- 4198137 TI - Permeability of Azotobacter vinelandii to cations and anions. PMID- 4198138 TI - The effects of propionate on sodium transport by the toad bladder. Evidence for a metabolic mode of action. PMID- 4198139 TI - Adenine nucleotide metabolism of blood platelets. 8. Transport of adenine into human platelets. PMID- 4198140 TI - Denaturation and reactivation of human carbonic anhydrases in guanidine hydrochloride and urea. PMID- 4198141 TI - Detection of proteolytic activity after isoelectric focusing in polyacrylamide gel. PMID- 4198142 TI - Modified erythrocytes in indirect haemagglutination with Neisseria gonorrhoeae antigen. PMID- 4198143 TI - Penicillin sensitivity of gonococci in Ethiopia. PMID- 4198144 TI - Intrarenal distribution of blood flow in the baboon: effect of noradrenaline and adrenergic blocking agents. PMID- 4198145 TI - On the localization of ribonucleases in bacteria. PMID- 4198146 TI - Skeletal muscle phosphorylase kinase deficiency: detection of a protein lacking any activity in ICR-IAn mice. PMID- 4198147 TI - Nutritional status of rural pre-school children in West Bengal: II clinical observations. PMID- 4198148 TI - Brief communication: processed soya flour as substitute for dry skim milk in the "protein packet" in the treatment of protein calorie malnutrition. PMID- 4198149 TI - [Cancer of the lower esophagus fistulized into an esophageal diverticulum]. PMID- 4198150 TI - Effect of Aspergillus flavus mycotoxin on Culex mosquito larvae. PMID- 4198151 TI - Larval mortality of Culex tarsalis and Aedes aegypti when reared with different concentrations of Tetrahymena pyriformis. PMID- 4198152 TI - Identification of members of the Culex pipiens complex by immunodiffusion and immunoelectrophoresis. PMID- 4198153 TI - Clinical response to disodium cromoglycate. A double blind study. PMID- 4198154 TI - Factors affecting the turnover of cerebral glycogen and limit dextrin in vivo. PMID- 4198155 TI - Isolation and characterization of an organ specific ribonucleoprotein from goat brain. PMID- 4198156 TI - Lysolecithin and sphingosinephosphoryl-choline in the metabolism of brain phospholipids of the rhesus monkey (Macaca mulatta): effects of development. PMID- 4198157 TI - [Lumbar vertebral scalloping in the course of Recklinghausen's disease]. PMID- 4198158 TI - [Maxillary sinus cancer therapy: contribution of curietherapy]. PMID- 4198159 TI - [A method of optimization of a protocol of irradiation in curietherapy]. PMID- 4198160 TI - [Results of radiotherapy of anal canal cancers]. PMID- 4198161 TI - Lactose content of tube feeding diets as a cause of diarrhea. PMID- 4198162 TI - Alveolar bone changes consequent to orthodontic forces. A tetracycline marking study. PMID- 4198163 TI - The treatment of self-induced photic epilepsy. PMID- 4198164 TI - Reconsideration of the role of serotonin in subarachnoid haemorrhage. PMID- 4198165 TI - Immunologic relationships of antihemophilic factor of different species detected by specific human and rabbit antibodies. PMID- 4198166 TI - Development of antilymphocyte sera by cross immunization of chimpanzees and baboons. PMID- 4198167 TI - The use of an immunoadsorbent in the isolation of Australia antigen. PMID- 4198168 TI - Tissue and organ culture studies of hepatitis type B. PMID- 4198169 TI - Radioimmunoprecipitation assay for Australia antibody. PMID- 4198170 TI - Hepatitis: intrahepatic expression of Au antigen and immune complexes in liver tissue. PMID- 4198171 TI - Australia antigen in cord blood. PMID- 4198172 TI - Australia antigen and antibody in laboratory and other hospital personnel. PMID- 4198173 TI - Blood bank service screening of Australia antigen and antibodies at Mainz, Germany. PMID- 4198174 TI - Repeated monitoring of Au-SH antigen in blood donors of Reggio Emilia. PMID- 4198175 TI - Low voltage counterimmunoelectrophoresis for the detection of Australia antigen. PMID- 4198176 TI - Amodification of the immunoelectrophoretic method in the detection of Australia antigen. PMID- 4198177 TI - Primates as model for human viral hepatitis: transmission of infection by human hepatitis B virus. PMID- 4198178 TI - Gas-chromatographic determination of selenium. PMID- 4198179 TI - Antithymocyte antisera globulin effect on human lymphoid neoplasia. PMID- 4198180 TI - Arthritis and HB Ag-positive hepatitis. PMID- 4198181 TI - Steroid-responsive hypercalcemia in disseminated bone tuberculosis. PMID- 4198182 TI - Metabolic and microcirculatory effects of glucagon in hypovolemic shock. PMID- 4198183 TI - Experience with elemental diet in the treatment of inflammatory bowel disease. Is this primary therapy? PMID- 4198184 TI - Energy-dependent accumulation of iron by isolated rat liver mitochondria. I. General features. PMID- 4198185 TI - Light-induced changes in the fluorescence yield of chlorophyll a in Anacystis nidulans. I. Relationship of slow fluorescence changes with structural changes. PMID- 4198186 TI - Chromatographic separation of two ionic strength dependent conformations of valine transfer ribonucleic acid of Bacillus subtilis. PMID- 4198187 TI - Selective reaction of glyoxal with guanine residues in native and denatured Escherichia coli 5S RNA. PMID- 4198188 TI - Formation of ribosomal particles in virginiamycin sensitive and resistant mutants of Bacillus subtilis. PMID- 4198189 TI - [Protective effect of pyrodoxal phosphate on Pseudomonas fluorescens aminobutyrate aminotransferase]. PMID- 4198190 TI - [Incidence of hepatitis-associated antigen (Australia antigen) in chronic inflammatory joint disease]. PMID- 4198191 TI - [Drug therapy of the atopic bronchial asthma in childhood]. PMID- 4198192 TI - A comparative clinical evaluation of hepatitis-associated antigen detection. PMID- 4198193 TI - Salivary immunoglobulins in Sjogren's syndrome. PMID- 4198194 TI - Measurements of concentrations of human serum innunoglobulins. PMID- 4198195 TI - Response of plasma histaminase activity to small doses of heparin in normal subjects and patients with hyperlipoproteinemia. AB - The release of histaminase activity in plasma after small intravenous of heparin was studied in 85 normal subjects and patients. In normal subjects, plasma histaminase activity (basal level, 1.7+/-0.1 U/ml, mean +/-SEM) increased 1.6+/ 0.2 U/ml after 10 U of heparin/kg, 8.5+/-2.4 U/ml after 20 U/kg, and 33+/-4.9 U/ml after 75 U/kg. The extent of the increase varied widely among individuals but in a particular individual the response was constant and dose-dependent. Histaminase activity rose to peak levels within 7-15 min and then declined exponentially with a half-life of 40-120 min. This pattern of response was also observed in two patients with the histaminase-producing tumor, medullary carcinoma of the thyroid. A significantly reduced response was observed, however, in 14 patients with type I hyperlipoproteinemia, a disorder in which high plasma triglyceride levels are associated with low postheparin plasma lipolytic activity. After 10 U heparin/kg, plasma histamine activity increased 0.5+/-0.2 U/ml, and after 75 U heparin/kg, 10.9+/-5.6 U/ml. In contrast, in 27 patients with other types of hyperlipoproteinemia in whom postheparin lipolytic activity was normal, the increase (2.4+/-0.6 U/ml) in plasma histaminase activity after 10 U heparin/kg was not significantly different from that of normal subjects. The reduced response of the plasma histaminase activity to heparin in patients with type I hyperlipoproteinemia did not appear to be due to the presence of lipemia or to an inhibitor of the enzyme in plasma. These findings suggest that many patients with type I hyperlipoproteinemia may have deficient release of both lipolytic and histaminase activities into plasma after heparin administration. PMID- 4198196 TI - A saturable, vasopressin-sensitive carrier for urea and acetamide in the toad bladder epithelial cell. AB - The permeability of the toad bladder to a series of isotopically labeled nonelectrolytes was determined in the presence of 150 mM unlabeled acetamide. Under these conditions, overall bladder function was unimpaired, as shown by a normal response to vasopressin of short-circuit current and permeability coefficient of [(3)H]water,[(14)C]ethanol, and [(14)C]propionamide. The permeability of the bladder to isotopic acetamide and urea, however, was significantly depressed by unlabeled acetamide, in both the absence and presence of vasopressin. These experiments indicate a competition between unlabeled and isotopic species for binding sites, and show the existence of a saturable, vasopressin-sensitive carrier for urea and acetamide in the epithelial cell membrane. PMID- 4198197 TI - Oral microbial profile of the marmoset. PMID- 4198198 TI - Solubility of calcified dental tissues and of calculus in EDTA and 2 percent NaF. PMID- 4198199 TI - Cellular mediators of anti-Listeria immunity as an enlarged population of short lived, replicating T cells. Kinetics of their production. AB - An intravenous immunizing infection with the facultative, intracellular parasite, Listeria monocytogenes results in the production in the spleen of a population of immunologically-committed lymphocytes which can adoptively immunize normal recipients against a lethal challenge infection. These cellular mediators of immunity are first produced in the spleen between days 2 and 4 of infection and reach peak production on day 6. Their production then progressively decreases until about day 20 when their presence can no longer be detected. Increased production of cellular mediators is coincident with major increases in cell division, cellularity, and spleen weight. Decreased production of cellular mediators, on the other hand, is associated with decreases in cell division, cellularity, and spleen weight. Again, the level of delayed sensitivity to Listeria antigens expressed by the host at any one time is proportional to the number of cellular mediators in the spleen. Increased production of cellular mediators is also associated with major increases in the total numbers of replicating T cells and B cells in the spleen. That the cellular mediators of immunity are part of the replicating T cell population, rather than the B cell population, is evidenced by their susceptibility to anti-theta serum and by their resistance to anti-Ig serum. Furthermore, they can be completely eliminated from the spleen by a brief pulse of the antimitotic drug, vinblastine. This study allows the conclusion that the cellular mediators of anti-Listeria immunity belong to an expanded population of rapidly dividing, short-lived T cells. It is suggested that they have the same properties as the T cell effectors of allograft immunity. PMID- 4198200 TI - Immunologic studies of the major nonimmunoglobulin protein of amyloid. I. Identification and partial characterization of a related serum component. AB - Antisera have been prepared against the major nonimmunoglobulin component of secondary and familial Mediterranean fever (FMF) associated amyloid which has been called A component or acid soluble fraction (ASF). The antisera were shown to be monospecific for ASF by precipitation of (125)I-labeled antigen and gave a reaction of identity with four different ASF preparations. The antisera were able to detect a circulating component in human serum that migrated in the alpha1 globulin region. This circulating component gave a line of identity with degraded ASF by double immunodiffusion. 57 normal sera and 89 sera from patients with diseases known to be frequently associated with amyloidosis were tested by immunodiffusion for the circulating ASF component. 7% of normal sera and 50-80% of the pathologic sera had elevated amounts of this component. Absorption studies showed that all normal sera probably have small amounts of this component while cord sera do not have detectable amounts. This component was partially purified and was shown to be slightly larger than albumin. The relation of the circulating component to the acid soluble fraction of amyloid is discussed. PMID- 4198201 TI - Phylogenetically associated residues within the VH3 subgroup of several mammalian species. Evidence for a "pauci-gene" basis for antibody diversity. AB - Immunoglobulin heavy chains from IgG pools of several mammalian species have been subjected to Edman degradation on an automated protein sequencer. The percentage of unblocked vs. blocked heavy chains was estimated from the yield of the invariant valine in the second position. Further analysis of these unblocked polypeptides unequivocally placed them in the V(HIII) subgroup on the basis of homology with known human heavy chain sequences. The mammals studied could be divided into three distinct categories on the basis of the distribution of the V(HIII) subgroup. In several species the V(HIII) subgroup could not be detected while, in others, virtually all of the heavy chains belonged to this subgroup. Several species had intermediate amounts with the level of the V(HIII) subgroup restricted to between 19 and 29% of the total pool. Within experimental error, all members of a given order had a similar V(HIII) subgroup distribution. Further amino acid sequence studies illustrated a high degree of structural homogeneity in the heavy chains of IgG isolated from pooled sera of a number of mammalian species. The very close amino acid sequence homologies of the amino terminal 24 residues of the various pools corroborated conclusions previously obtained using several myeloma proteins from some of these same species. In particular, certain phylogenetically associated residues were identifiable at characteristic positions in the pools in confirmation of their identification in the myeloma proteins. The simplest assumptions would suggest that these findings are more compatible with a pauci-gene than a multi-gene basis for the generation of antibody diversity. PMID- 4198202 TI - The nature of the antibody response to Yersinia enterocolitica serotype IX in cattle. AB - The nature of the antibody response of cattle to the antigen of Yersinia enterocolitica IX cross-reacting with Brucella spp. was examined. Density gradient ultracentrifugation, ion-exchange chromatography, antibody adsorption and elution and disulphide bond reduction tests showed that both 19 S IgM and 7 S IgG(1) and IgG(2) antibodies were produced in response to the cross-reacting antigen. The highest titres of cross-reacting antibodies were detected by the agglutination and Coombs antiglobulin tests. Production of complement-fixing and precipitating antibodies cross-reacting with Br. abortus was transient and high titres were not attained.In contrast, although infection with Br. abortus also evoked cross-reacting antibodies of the IgM and IgG classes, much higher titres were produced in the complement fixation and precipitation tests and these persisted for long periods. At all stages of the serological response to both organisms, the two infections could be differentiated by the quantitative Rose Bengal plate test. PMID- 4198203 TI - Typing of Pseudomonas aeruginosa: comparison of the phage procedure with the pyocine technique. AB - Two hundred and sixty strains of Pseudomonas aeruginosa were isolated from patients of the Asaf Harofe Government Hospital. The strains were typed by phage technique and 64 of them were also typed according to pyocine sensitivity. The two methods proved complementary, and reduced the number of untypable strains. Phage typing was performed with both routine test dilution (RTD) and more concentrated phage suspensions. The most reliable results were obtained at 100 RTD. PMID- 4198204 TI - A common antigenic constituent in various purified Salmonella endotoxins. PMID- 4198205 TI - Host resistance to bacterial endotoxemia: mechanisms in endotoxin-tolerant animals. PMID- 4198206 TI - Factors in normal human serum that promote bacterial phagocytosis. PMID- 4198207 TI - Escherichia coli bacteremia in the squirrel monkey: demonstration of a complement dependent neutrophil response. PMID- 4198208 TI - Head injury in the chimpanzee. 1. Biodynamics of traumatic unconsciousness. PMID- 4198209 TI - Head injury in the chimpanzee. 2. Spontaneous and evoked epidural potentials as indices of injury severity. PMID- 4198210 TI - Feedlot performance and blood plasma amino acid patterns in beef steers fed diethylstilbestrol under ad libitum, restricted, and compensatory conditions. PMID- 4198211 TI - Effects of dietary zinc on zinc enzymes in the rat. PMID- 4198212 TI - Effect of chelating agents on chromium absorption in rats. PMID- 4198213 TI - Long-standing traumatic lesions of the hypothalamus. PMID- 4198214 TI - Influence of dietary protein deficiency on phagocytic activity of the reticulo endothelial cells. PMID- 4198215 TI - Self-administration of acetylsalicylic acid and combinations with codeine and caffeine in rhesus monkeys. PMID- 4198216 TI - Neurofibromatosis of the bladder. PMID- 4198217 TI - Presence of beta-aspartyl N-acetyl glucosamine amido hydrolase in mammalian spermatozoa. PMID- 4198218 TI - Release of LH by synthetic LH-RH in the monkey, Macaca fascicularis. PMID- 4198219 TI - The association of zinc with some components of boar vesicular secretion and seminal plasma. I. Gel-filtration and dialysis studies. PMID- 4198220 TI - Cellular location of the lipoteichoic acids of Lactobacillus fermenti NCTC 6991 and Lactobacillus casei NCTC 6375. PMID- 4198221 TI - [Cervico-prostatic cryogenic surgery. Report on about 100 cases]. PMID- 4198222 TI - Brain-damaging potential of protein hydrolysates. PMID- 4198223 TI - Public accountability and reporting systems in Medicare and other health programs. PMID- 4198224 TI - Safety of hydrolysates in parenteral nutrition. PMID- 4198225 TI - Positive brain scans in children with idiopathic focal epileptic seizures. PMID- 4198226 TI - Transmissible mink encephalopathy agent in squirrel monkeys. Serial electroencephalographic, clinical and pathologic studies. PMID- 4198227 TI - [Bacterial flora in aplastic anemia. Consequences on antibiotherapy]. PMID- 4198228 TI - [Determination of the presence of mycoplasma in cellular cultures by direct isolation]. PMID- 4198229 TI - Control circuits for determination and transdetermination. PMID- 4198230 TI - Fabry's disease: general clinical aspects. PMID- 4198231 TI - The need for further data. PMID- 4198232 TI - Cytological, biochemical and bacteriological data of the hemolymph of Vespaorientalis. PMID- 4198233 TI - [Overdosage of anticonvulsants]. PMID- 4198234 TI - Factors influencing neonatal infection by hepatitis B virus. PMID- 4198235 TI - [Regional radiotherapy of malignant lymphogranuloma. Technic and case reports]. PMID- 4198236 TI - [Therapy of various clinical situations especially in the course of Hodgkin's disease]. PMID- 4198237 TI - [Cytogenetic study of paroxysmal nocturnal hemoglobinuria (PNH)]. PMID- 4198238 TI - [Autoimmune hemolytic anemia during therapy with alpha-methyldopa]. PMID- 4198239 TI - [Therapy of acute leukosis with cytarabine]. PMID- 4198240 TI - [Essential cryoglobulinemia]. PMID- 4198241 TI - [Hemolytic disease in a newborn Du infant]. PMID- 4198242 TI - [Hemorrhagic syndrome due to defective platelet aggregation in chronic lymphatic leukemia of the splenomegalic variety]. PMID- 4198243 TI - [Splenic contraction due to adrenalin as a possible diagnostic test before splenectomy in subjects with a thrombopenic hemorrhagic syndrome]. PMID- 4198244 TI - [Idiopathic recurrent thrombopenias. Clinico-hematological study]. PMID- 4198245 TI - [New abnormal hemoglobin (Hb Abruzzo) in a subject with hemolytic syndrome of the Mediterranean type and distinct polycythemia]. PMID- 4198246 TI - [Relationship between chromosome Y and the nucleolus in the peripheral blood lymphocytes]. PMID- 4198247 TI - [Identification of the sex chromosome formula in granulocytes of the peripheral blood]. PMID- 4198248 TI - [Diagnosis of paternity from peripheral blood granulocytes: study of fluorescence with the use of quinacrine]. PMID- 4198249 TI - [Significance of the so-called small clubs in granulocytes of male subjects]. PMID- 4198250 TI - A cytogenetic analysis of oocytes from Macaca mulatta and nemestrina matured in vitro. PMID- 4198251 TI - Detection of Australia antigen in Indian childhood cirrhosis. PMID- 4198252 TI - Role of bound ADP in photosynthetic ATP formation by chromatophores from Rhodospirillum rubrum. PMID- 4198253 TI - Internal localization of nucleoside-catabolic enzymes in Escherichia coli. PMID- 4198254 TI - Two types of soluble malic enzyme in rat tissues. PMID- 4198255 TI - Immunoassay of thyroxine in unextracted human serum. PMID- 4198256 TI - Progressive decrease in serum triiodothyronine concentrations with human aging: radioimmunoassay following extraction of serum. PMID- 4198257 TI - Supervoltage orbital radiotherapy for Graves' ophthalmopathy. PMID- 4198258 TI - A goitrous subject with defective synthesis of diiodotyrosine due to thyroglobulin abnormalities. PMID- 4198259 TI - Serum levels of luteinizing hormone, follicle-stimulating hormone and progesterone throughout the mentrual cycle of rhesus monkeys. PMID- 4198260 TI - Elevations in plasma growth hormone concentration after luteinizing hormone releasing hormone (LRH) in patients with active acromegaly. PMID- 4198261 TI - [Statistical observation on chronological changes of sensitivity of various bacteria to antibiotics. 1. Gram negative bacilli; Escherichia coli, Bacillus pneumoniae, Proteus vulgaris, Alcaligenes faecalis, Cloaca, Providencia, Citrobactor, Pseudomonas aeruginosa (1966-71)]. PMID- 4198262 TI - [On the middle lobe syndrome including a traction oesophageal diverticulum in a leprosy patient]. PMID- 4198263 TI - [Characterization of L chains in myelomatous human urine. Physicochemical and immunological study]. PMID- 4198264 TI - [Use of sorbitol (1-gulitol) in parenteral feeding]. PMID- 4198265 TI - [Survival of some terrestrial microorganisms in space]. PMID- 4198266 TI - Synthesis of lysine from alpha, epsilon-diaminopimelic acid by mixed ciliated rumen protozoa. PMID- 4198267 TI - Light induced changes in ionic flux in the retinal rod. PMID- 4198268 TI - Gonococcal infections in the female. PMID- 4198269 TI - Gonorrhea among females in a military population. PMID- 4198270 TI - Gestational meconium in the high-risk pregnancy. PMID- 4198271 TI - Photoreactivation of Drosophila melanogaster embryonic cells. PMID- 4198272 TI - [Possibilities for the assessment of chronic obstructive airway diseases through the analyses of bronchial mucus]. PMID- 4198273 TI - [Treatment of circulatory venous diseases: double-blind study with Sandovene]. PMID- 4198274 TI - Gap junctions between photoreceptor cells in the vertebrate retina. AB - In the outer plexiform layer of the retina the synaptic endings of cone cells make specialized junctions with each other and with the endings of rod cells. The ultrastructure of these interreceptor junctions is described in retinas of monkeys, rabbits, and turtles, in thin sections of embedded specimens and by the freeze-fracturing technique. Cone-to-rod junctions are ribbon-like areas of close membrane approximation. On either side of the narrowing of the intercellular space, the junctional membranes contain a row of particles located on the fracture face A (cytoplasmic leaflet), while the complementary element, a row of single depressions, is located on fracture face B. The particle rows are surrounded by a membrane region that is devoid of particulate inclusions and bears an adherent layer of dense cytoplasmic material. Cone-to-cone junctions in some places are identical to cone-to-rod junctions, while in other places they closely resemble typical gap junctions (nexus). Interreceptor junctions, therefore, represent a morphological variant of the gap junction, and probably mediate electrotonic coupling between neighboring photoreceptor cells. PMID- 4198275 TI - The use of iodinated RNA for gene localization. AB - Carrier-free iodination of 5S RNA with (125)I yields a probe suitable for use in cytological RNA-DNA hybridization studies. The genes coding for 5S ribosomal RNA in Drosophila could be localized by autoradiography after a 2-day exposure, whereas a 2-month exposure is needed when the best available [(3)H]RNA is used. The procedure introduces one covalently bound (125)I atom per 100 nucleotides, resulting in a specific activity of over 10(8) dpm/mug of RNA. The method may be readily applied to other problems involving molecular hybridization techniques. PMID- 4198276 TI - Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation. AB - The activity of the sigma subunit of the RNA polymerase of Bacillus subtilis decreases markedly during the first 2 hr of sporulation. Moreover, sigma activity remains deficient throughout the sporulation process and in dormant spores. The time course of changes in RNA polymerase during sporulation indicates that alterations in the core of RNA polymerase occur after the loss of sigma activity. Core RNA polymerase purified after the second and before the ninth hour of sporulation fails to respond to vegetative sigma subunit in vitro and contains variable amounts of a 110,000-dalton polypeptide in place of the beta' subunit. Core RNA polymerase purified from dormant spores has a subunit structure indistinguishable from vegetative core enzyme.RNA polymerase purified by antibody precipitation from an extract of a mixture of sporulating and excess vegetative cells separately labeled with two different radioisotopes contains beta' subunit and no 110,000-dalton polypeptide. However, RNA polymerase purified from sporulating bacteria in the absence of excess vegetative cells progressively loses the beta' subunit at each stage of purification even in the presence of the protease inhibitor, phenylmethyl sulfonyl fluoride. These findings suggest that the alteration of the beta' subunit is due to proteolysis in vitro. PMID- 4198278 TI - The aflatoxins and human liver cancer. PMID- 4198277 TI - Relative orientation with respect to the centromere of ribosomal RNA genes of the X and Y chromosomes of Drosophila melanogaster. AB - We tested for recombination within the DNA that codes for ribosomal RNA (rDNA) on the X and Y chromosomes of Drosophila melanogaster. The criterion was the appearance of intermediate bb alleles on X-Y recombinants from wild bb(+) and lethal bb(1) loci carried on parental chromosomes. Recombination within the rDNA occurs only when the rDNA of the X chromosome is inverted. We conclude that rDNAs of normal X and Y chromosomes have opposite orientation with respect to the centromere. The implications of this observation are discussed. PMID- 4198279 TI - [Occipito-cervical abnormalities (apropos of 2 cases of atlas assimilation)]. PMID- 4198280 TI - Evaluation of environmental health programmes: report of a WHO scientific group. PMID- 4198283 TI - Microangiopathy in the experimentally diabetic animal. PMID- 4198282 TI - [Therapeutic results of H.M. 51 Sandoz (Visergil) in gerontopsychiatry]. PMID- 4198284 TI - Microangiopathy in animals with spontaneous diabetes. PMID- 4198285 TI - Pseudo-leukocytosis associated with cryoglobulinemia. PMID- 4198286 TI - Immune serum globulin--a cause for anti-Rh (D) passive sensitization. PMID- 4198287 TI - Membrano-proliferative glomerulonephritis associated with persistent viral hepatitis. PMID- 4198288 TI - Mechanisms of drug-enzyme interactions. PMID- 4198289 TI - "IGF" in food allergy? PMID- 4198290 TI - [Immunoelectrophoretic diagnosis of visceral leishmaniasis with the use of a hydrosoluble antigenic extract of Leishmania donovani. Preliminary results]. PMID- 4198291 TI - [Rigidity and decerebration. I. Anatomo-physiological concepts]. PMID- 4198292 TI - [Evaluation of diagnostic methods for encephalitis rabies]. PMID- 4198293 TI - Microcirculation of monkey pancreas with special reference to the insulo-acinar portal system. A scanning electron microscope study of vascular casts. PMID- 4198294 TI - The effect of trimazosin in essential hypertension. PMID- 4198295 TI - Effects of perhexiline maleate in patients with angina pectoris unrelieved by other antianginal agent. PMID- 4198296 TI - Double-blind clinical evaluation of mazindol, dextroamphetamine, and placebo in treatment of exogenous obesity. PMID- 4198297 TI - Oral aminophylline and dikydroxypropyl theophylline in reversible obstructive airway disease: a single-dose, double-blind, crossover comparison. PMID- 4198298 TI - Response to a single intravenous dose versus multiple intramuscular administration of iron-dextran complex: a comparative study. PMID- 4198299 TI - A double-blind comparison of ethoheptazine citrate, propoxyphene hydrochloride, and placebo. PMID- 4198300 TI - Clinical trial of a new anti-inflammatory drug in otolaryngology. PMID- 4198301 TI - Irradiation synovectomy: clinical study of 67 knee effusions intra-articularly irradiated with 90 Y resin. PMID- 4198302 TI - Treatment of premenopausal endometrial hyperplasia by a combination of a long acting estrogen and a cyclic progestogen. PMID- 4198304 TI - The extrapyramidal neuroleptic syndrome: description and measurement. PMID- 4198303 TI - Influence of treatment on symptomatology and correlated electroencephalographic (EEG) changes in the aged. PMID- 4198305 TI - Preanesthetic medication in elective surgery: comparison of intravenous diazepam with meperidine. PMID- 4198306 TI - Clorazepate dipotassium, diazepam and placebo in chronic anxiety. PMID- 4198307 TI - The use of N-demethyldiazepam in outpatients suffering from insomnia. PMID- 4198308 TI - Metiapine in acute schizophrenic patients. PMID- 4198309 TI - Metiapine: the evaluation of the antipsychotic properties of a new neuroleptic. A pilot study. PMID- 4198310 TI - Potentiation of haloperidol by -methyldopa in the treatment of schizophrenic patients. PMID- 4198311 TI - Comparable therapeutic efficacy of tryptophan and imipramine: average therapeutic ratings versus "true" equivalence. An important difference. PMID- 4198312 TI - The computer analyzes two psychotherapeutic agents in anxiety-depressed states. PMID- 4198313 TI - A multicenter investigation of lorazepam in anxiety neurosis. PMID- 4198314 TI - Effects of molindone on CNS structures: neurophysiological and behavioral correlations. PMID- 4198315 TI - The protein needs of malnourished children. PMID- 4198316 TI - Dipropylacetate (Depakine, Ergenyl) in the treatment of epilepsy. PMID- 4198317 TI - Superiority of clonazepam over diazepam in experimental epilepsy. PMID- 4198318 TI - Principles of methodical studies on capillaries in the light of the immunomorphogenesis of the capillary-haemopoietic system. I. Immunobiogenetic studies. PMID- 4198319 TI - [Feto-meternal conflict in the ABO, Rh and HL-A systems. I. Preliminary clinical observations of the gestation course]. PMID- 4198320 TI - Intestinal carriage of Klebsiella and pseudomonas in burned children and their comparative role in nosocomial infection. PMID- 4198321 TI - Pattern formation in the blue-green alga, Anabaena. I. Basic mechanisms. PMID- 4198322 TI - Temperature-sensitive RNA polymerase of a mammalian cell mutant. PMID- 4198324 TI - Immunogenetic and electrophoretic studies with extracts of different adult Culex pipiens strains. PMID- 4198323 TI - Acetylcholinesterase in human erythroid cells. PMID- 4198325 TI - A comparative study of diamine oxidase in amniotic fluid and serum in normal pregnancy and in pregnancy complicated by rhesus iso-immunization. PMID- 4198326 TI - [Acute subclavian and axillary vein thrombosis during long-term glucagon infusion]. PMID- 4198327 TI - [Pigeons as carriers of paratyphoid bacilli in the City of Cracow]. PMID- 4198328 TI - [Diagnosis of malaria in monkeys by means of the immunofluorescence method with Plasmodium gallinaceum antigen]. PMID- 4198329 TI - [Microbiological assay of various phenothiazine derivatives]. PMID- 4198331 TI - [Effect of some factors on the efficacy of ferrocyanides used for the removal of radiocesium from the organism]. PMID- 4198330 TI - Premature labour at Groote Schuur Hospital. PMID- 4198332 TI - [Effect of ionizing radiation on regulatory mechanisms of the cellular regeneration processes]. PMID- 4198333 TI - [Enzymatic systems of DNA biosynthesis in a irradiated organism]. PMID- 4198334 TI - [Biochemical diagnosis of acute irradiation disease in pigs]. PMID- 4198335 TI - [Hematological changes in peripheral blood in non-contact burn model in rats]. PMID- 4198337 TI - [Tracheal injury caused by prolonged artificial respiration]. PMID- 4198336 TI - Dairy herd environment and the control of mastitis. PMID- 4198338 TI - [Endoscopy of the upper and middle respiratory tract while an indwelling endotracheal tube is in position]. PMID- 4198339 TI - Plasma and urine ribonuclease as a measure of nutritional status in children. PMID- 4198340 TI - Effects of dietary supplementation of monosodium glutamate on infant monkeys, weanling rats, and suckling mice. PMID- 4198341 TI - Influence of a viral enteric infection on the aminogram and pathology of protein calorie malnutrition in the pig. PMID- 4198342 TI - International and local growth standards. PMID- 4198343 TI - Use of the indirect fluorescent antibody technique in serologic studies of Theileria lawrencei infections in cattle. PMID- 4198344 TI - Transmissible drug resistance in Enterobacteriaceae isolated from healthy nonhuman primates. PMID- 4198345 TI - Naturally occurring cholelithiasis in a rhesus monkey and its effects on plasma and biliary lipid concentrations. PMID- 4198346 TI - Characterization of Listeria monocytogenes serotype 5. PMID- 4198347 TI - Familial chronic interstitial pneumonia. PMID- 4198348 TI - A new "double ring" screening test for alpha1-antitrypsin variants. PMID- 4198349 TI - Productivity of prolonged follow-up after chemotherapy for tuberculosis. PMID- 4198350 TI - Primary drug-resistant tuberculosis in children, 1961 to 1971. A comparison of the frequency of primary drug-resistant tuberculosis among children observed during the period of transition from long-term to short-term hospitalization of adults with infectious tuberculosis. PMID- 4198351 TI - A study of mycobacterial species isolated from patients with chronic respiratory disease. PMID- 4198352 TI - Scanning electron microscopy of mycobacteria. PMID- 4198353 TI - Effect of age on the fatty acids C14 to C19 of mycobacteria. PMID- 4198354 TI - Species differences in the diurnal rhythmicity of courtship behaviour within the melanogaster group of the genus Drosophila. PMID- 4198355 TI - Surgical anatomy of the biliary tract. As demonstrated by peroperative cholangiography. PMID- 4198356 TI - The location of N-acetylgalactosamine in the walls of Bacillus subtilis 168. AB - The N-acetylgalactosamine in the walls of Bacillus subtilis 168 occurs in two polymers. One of these contains N-acetylgalactosamine, glucose and phosphorus and is attached to the peptidoglycan through an alkali-labile bond; preliminary studies indicate that a repeating unit of this polymer is glucosyl-N acetylgalactosamine 1-phosphate. N-Acetylgalactosamine is also associated with the peptidoglycan in a component that is not converted into the free sugar or other soluble compounds on treatment of the walls with alkali. The two polymers containing N-acetylgalactosamine are released on autolysis of the walls and can be separated by ion-exchange chromatography. As glucose 6-phosphate is produced by gentle hydrolysis of the wall with acid a third phosphate polymer, poly(glucose 1-phosphate), may occur in this wall. However, as no polymer with this structure could be separated from that containing galactosamine, its existence has not been established unequivocally. The methods described permit the study of variations in N-acetylgalactosamine content with respect to growth conditions. PMID- 4198357 TI - Regulation of C metabolism by L-methionine in Saccharomyces cerevisiae. AB - 1. The concentrations of folate derivatives in aerobic cultures of Saccharomyces cerevisiae (A.T.C.C. 9763) were determined by microbiological assay employing Lactobacillus casei (A.T.C.C. 7469) and Pediococcus cerevisiae (A.T.C.C. 8081). Cells cultured in media lacking l-methionine contained higher concentrations of folate derivatives than cells grown in the same media supplemented with 2.5mumol of l-methionine/ml. The concentrations of highly conjugated derivatives were also decreased by supplementing the growth medium with l-methionine. 2. DEAE-cellulose column chromatography of extracts prepared from cells grown under these conditions revealed that the concentrations of methylated tetrahydrofolates were drastically decreased by the methionine supplement. Smaller decreases were also observed in the concentrations of formylated and unsubstituted derivatives. 3. The concentrations of four enzymes of C(1) metabolism were compared after 6h of growth in the presence and in the absence of l-methionine (2.5mumol/ml). The specific activities of formyltetrahydrofolate synthetase, methylenetetrahydrofolate reductase and serine hydroxymethyltransferase were not altered by this treatment but that of 5-methyltetrahydrofolate-homocysteine methyltransferase was decreased by approx. 65% when l-methionine was supplied. The activities of 5-methyltetrahydrofolate-homocysteine methyltransferase, serine hydroxymethyltransferase and formyltetrahydrofolate synthetase were not appreciably altered by l-methionine in vitro. In contrast this amino acid was found to inhibit the activity of methylenetetrahydrofolate reductase. 4. Feeding experiments employing sodium [(14)C]formate indicated that cells grown in the presence of exogenous methionine, although having less ability to convert formate into methionine, readily incorporated (14)C into serine and the adenosyl moiety of S-adenosylmethionine. 5. It is suggested that exogenous l-methionine controls C(1) metabolism in Saccharomyces principally by regulation of methyl-group biogenesis within the folate pool. PMID- 4198359 TI - A possible ribosomal-directed regulatory system in Euglena gracilis. Carbon dioxide fixation. AB - It was shown that cycloheximide inhibits CO(2) fixation in Euglena cells in the dark, but no effect of chloramphenicol was found. The light-dependent CO(2) fixation was inhibited by chloramphenicol and by large amounts of cycloheximide, but was stimulated by small amounts of cycloheximide. The presence of the stimulatory concentration of cycloheximide abolished the inhibition effect of high concentrations of chloramphenicol. The results indicate that the light dependent CO(2) fixation is controlled by a repression-derepression regulatory system, which seems to be independent of chlorophyll synthesis. PMID- 4198358 TI - A possible ribosomal-directed regulatory system in Euglena gracilis. Chlorophyll synthesis. AB - Cycloheximide at concentrations of 0.1-100mum stimulated chlorophyll synthesis when dark-grown cells of Euglena were illuminated. Chloramphenicol (1-4mm) inhibited chlorophyll synthesis. The effect of cycloheximide on the incorporation of [(14)C]leucine into material insoluble in trichloroacetic acid, and its failure to affect the incorporation of [(32)P]orthophosphate into such material in short incubations, are interpreted as evidence that cycloheximide specifically inhibits protein synthesis by 80S ribosomes. Since the inhibitory effect of chloramphenicol on chlorophyll synthesis is counteracted by the presence of cycloheximide, it is suggested that chlorophyll synthesis is subject to control by a cytoplasmic repressor synthesized on 80S ribosomes, and to a de-repressor synthesized on 70S ribosomes. PMID- 4198361 TI - Selective extraction of polymers from cell walls of gram-positive bacteria. AB - Brief heating of Bacillus Licheniformis cell walls at 100 degrees C in aqueous buffers of pH3.0-4.0 removes some polymers but not others from the mucopeptides. For example, relatively undegraded teichuronic acid can be extracted at 100 degrees C in 20min at pH3.0 whereas the teichoic acids are not removed. Similar specificity can be shown with walls from three other species of micro-organism. PMID- 4198360 TI - Kinetics of the diamine oxidase reaction. AB - 1. The oxidation of p-dimethylaminomethylbenzylamine was followed spectrophotometrically by measuring the change in E(250) caused by the p dimethylaminomethylbenzaldehyde produced under a wide variety of experimental conditions. 2. The effect of variations in concentrations of both substrates (amine and oxygen) and all products (aminoaldehyde, hydrogen peroxide and ammonia) on this reaction was studied and the results used to develop a formal mechanism. 3. The nature of the rate-limiting step was elucidated by studying the effects of alterations in ionic strength, dielectric constant and deuterium substitution on the velocity of the forward reaction. 4. Thermodynamic activation energy parameters were obtained at several pH values from the effects of temperature on the reaction. PMID- 4198362 TI - Comparative study of the optical rotatory dispersion and circular dichroism of human erythrocyte carbonic anhydrases A and B, and conformational variants B1 and B2. PMID- 4198363 TI - Metabolic studies of (75Se)selenomethionine and (75Se)selenite in the rat. PMID- 4198364 TI - Protein requirements of growing lambs. PMID- 4198365 TI - A device and technique for urethrography in the female. PMID- 4198366 TI - Osteoporosis and long-term corticosteroid therapy. AB - Sequential measurements of total body calcium by in-vivo neutron activation analysis were made in five patients treated with corticosteroid drugs for severe inflammatory disease. No evidence of osteoporosis was seen to develop during the course of 20-33 months of study. In one case a substantial rise in total body calcium was found. PMID- 4198367 TI - Significance of hyperamylasaemia and abdominal pain in diabetic ketoacidosis. AB - An analysis of 35 consecutive episodes of diabetic ketoacidosis confirmed the frequent high levels of serum amylase in this condition. Serum amylase was raised during 21 episodes (60%), and in six instances (17%) the peak level exceeded 1,000 Somogyi units per 100 ml. Hyperamylasaemia was more often found when the initial blood sugar exceeded 500 mg/100 ml, or when the onset of the episode had been relatively acute (less than 48 hours). There was no conclusive evidence in any patient to support a diagnosis of acute pancreatitis and other explanations for the hyperamylasaemia are discussed. Even grossly raised amylase levels were not associated with increased mortality or morbidity. PMID- 4198368 TI - Drugs for angina pectoris. PMID- 4198369 TI - Retrograde transneuronal degeneration of optic fibers and their terminals in lateral geniculate nucleus of rhesus monkey. PMID- 4198370 TI - Optic chiasm section affects discriminability of asymmetric patterns by monkeys. PMID- 4198371 TI - [Relationship between the presence of endogenous pentoses in the intestine and the effect of carbohydrates on calcium absorption]. PMID- 4198372 TI - [Localization in layer V of Rexed cells of crossed spinothalamic bundle orgin in Macaca]. PMID- 4198373 TI - [Bacteriological studies on wall to wall carpeting. I. Significance of thread and texture of wall to wall carpeting for the disinfection]. PMID- 4198374 TI - [Development of transplantated gonads in axolot limbs. Effect of irradiation and amputation of the host limb]. PMID- 4198375 TI - [In vitro differentiation of allantoid epithelium associated with different digestive tract mesenchymes in the chick embryo]. PMID- 4198376 TI - [Relationship between metamorphosis and thickness of the enamel layer on teeth in urodele amphibians]. PMID- 4198377 TI - [Hermaphroditism in allogenic chimerae in the urodele amphibian Pleurodeles waltii Michah]. PMID- 4198378 TI - [Studies of glycoproteins. Determination of the peptide sequence of the B glycopeptide isolated from chymotrypsic hydrolysates of human serum transferrin (serotransferrin)]. PMID- 4198379 TI - [Acetylcholine secretion induced by scorpion venom in the guinea pig ileum and its suppression by tetrodotoxin]. PMID- 4198380 TI - [Induction and prevention of allergic experimental encephalomyelitis in guinea pigs. Relationship with in vitro induced injuries and with class and specificity of the autoantibodies produced]. PMID- 4198381 TI - [Vaccination of the cinocephal monkey Papio papio against plague with a Yersinia pestis EV strain supernatant]. PMID- 4198382 TI - [Apparent polyspermia with falsely elevated fertility index. Correction of the index applied to those peculiar cases]. PMID- 4198383 TI - Xenotransplantation of established human endometrial cells into newborn hamsters. PMID- 4198384 TI - Haptenic activity of L-phenylalanine mustard. PMID- 4198385 TI - Clinical laboratory use of differential light scattering. I. Antibiotic susceptibility testing. PMID- 4198386 TI - Uptake of protein in swallowed amniotic fluid by monkey fetal intestine in utero. PMID- 4198387 TI - [On the histochemical and microchemical demonstration of beta-galactosidase by means of 1-naphthyl-beta-galactopyranoside]. PMID- 4198388 TI - Bacteriological evaluations of swine exposed to lethal levels of gamma radiation. PMID- 4198389 TI - Chelated trace minerals for G-F swine. PMID- 4198390 TI - Physico-chemical characteristics and regional distribution studies of GP-350, a soluble sialoglycoprotein from brain. PMID- 4198391 TI - Immunochemical studies on glutamic acid decarboxylase (EC 4.1.1.15) from mouse brain. PMID- 4198392 TI - The effects of changes in arterial plasma calcium concentration on submandibular secretory potentials. AB - 1. The concentration of Ca in the arterial blood plasma perfusing submandibular glands of anaesthetized cats and possums (Trichosurus vulpecula) was altered by constant-rate close arterial injection of isotonic CaCl(2) or EDTA solutions.2. There were no significant changes in the resting potentials of surface acinar cells in either species when the arterial plasma Ca concentration was altered over the range 0-30 mM.3. Secretory potentials in response to parasympathetic stimuli and close arterial injection of ACh were reduced and finally abolished during EDTA injection, but temporarily restored by injection of CaCl(2).4. Secretory potentials in response to 1 Hz parasympathetic stimuli in the cat were enhanced by increasing the gland arterial Ca concentration up to 5 mM; but responses to 10 Hz stimuli or close arterial ACh injection were not affected. There was no such enhancement of secretory potentials in the possum.5. Increase in the gland arterial plasma Ca concentration above 5 mM caused reduction in the amplitudes of the secretory potentials to all stimuli in both species, until they were abolished at 7-10 mM in the possum and 15-20 mM in the cat.6. In both species, increase in the gland arterial plasma Ca concentration caused increase in the gland blood flow and enhancement of the vasodilator effects of parasympathetic stimuli and ACh injection. EDTA injection was sometimes associated with a vasoconstrictor response to parasympathetic stimuli.7. It is concluded that the secretory potentials, but not the resting potentials, of submandibular secretory cells require the presence of Ca in the interstitial fluid. It is suggested that Ca affects both the release of transmitter and at higher concentration the mechanism by which it activates the secretory cells. PMID- 4198394 TI - [Nursing specialist in obstetrical nursing]. PMID- 4198393 TI - Functional studies of splenic and internal mammary artery implants in canine hearts. PMID- 4198395 TI - [Bedside nursing. Nursing of patients with spinal cord injuries. Early ambulation and social rehabilitation]. PMID- 4198396 TI - [Bedside nursing. Psychological process and nursing of aged patients in the terminal stage of cancer]. PMID- 4198397 TI - [Bedside nursing. Assistance of tuberculosis patients apprehensive of life in the hospital]. PMID- 4198399 TI - [Clinical conference. 7. Yokahama Municipal Hospital. An aged anemia patient unable to tolerate the recumbent position due to dyspnea]. PMID- 4198398 TI - [Bedside nursing. Bed arrangement and apprehension of the patient. A patient with breast cancer]. PMID- 4198400 TI - [Defecation of patients with cerebral apoplexy]. PMID- 4198401 TI - [Blood pressure changes in postural shifts]. PMID- 4198402 TI - [Re-evaluation of practical methods of patient assistance in nursing. 2]. PMID- 4198403 TI - [Psychology in nursing. 7. Patience expected in psychiatric nursing]. PMID- 4198404 TI - [Breakdown of the social welfare budget in Japan. 2]. PMID- 4198406 TI - [Pathophysiology of various diseases. 4. Obesity]. PMID- 4198405 TI - [Gerontology. 7. Rehabilitation of the aged]. PMID- 4198407 TI - [Nurse and laboratory diagnosis. 12. Chemical analysis. 2. Diseases in adults and laboratory diagnosis]. PMID- 4198408 TI - [Introduction to life science. 7. Life in molecular biology]. PMID- 4198409 TI - [Death and nursing. 7. Clinical course of death. (2). Personal involvement of the physician beyond the professional level causing friction with the family]. PMID- 4198410 TI - [Introduction to group dynamics in nursing. 16. Characteristics of group dynamic process among Japanese]. PMID- 4198411 TI - [Medicine and civilization. 7. Physician-patient relationship]. PMID- 4198412 TI - [Assistance in natural urination and innovation in the underwear following surgery of uterine cancer]. PMID- 4198414 TI - [The national social welfare budget. 5. Public assistance and medical assistance]. PMID- 4198413 TI - [On visiting places associated with Florence Nightingale. 2]. PMID- 4198415 TI - [Gerontology. 8. Neurologic diseases and cerebral apoplexy in the aged]. PMID- 4198416 TI - [Pathophysiology of various diseases. 5. Anorexia]. PMID- 4198417 TI - [Introduction to the study of human development. 1. Definition of human development]. PMID- 4198418 TI - [Transfer technic. 1. Definition of transfer technic]. PMID- 4198419 TI - [Re-evaluation of practical methods of patient assistance in nursing. 3]. PMID- 4198421 TI - [Death and nursing. 8. Practice of nursing of terminal cases. (1). Teamwork in facing death]. PMID- 4198420 TI - [Psychology in nursing. 8. Regression during hoospitalization and identification of patients in psychiatric wards]. PMID- 4198422 TI - [Introduction to group dynamics in nursing. 17. Overview of the studies of group dynamics and its applications]. PMID- 4198423 TI - [Medicine and civilization. 8. Changes in concept formation in the modern society]. PMID- 4198425 TI - [Bedside nursing. Nursing of patients with progressive senile dementia]. PMID- 4198424 TI - [Rehabilitation nursing]. PMID- 4198426 TI - [Bedside nursing. Meeting the needs of complaining patients who have been hospitalized for extended periods]. PMID- 4198427 TI - [Bedside nursing. Nursing of aged patients with enterostomies]. PMID- 4198428 TI - [Bedside nursing. Helping the patient apprehensive of various neurosurgical tests]. PMID- 4198430 TI - [Clinical conference. 8. The National Cancer Center. Supplementary feeding of the patient fitted with a feeding tube for an extended period]. PMID- 4198429 TI - [Bedside nursing. Feeding training of infants with nursing difficulties]. PMID- 4198431 TI - [Introduction and study of foreign literature. 8. "Topical hyperbaric oxygen for decubitus ulcer"]. PMID- 4198432 TI - Treatment for hypertension. PMID- 4198433 TI - Quantitative uptake measurements with a shadow shield whole-body counter. PMID- 4198434 TI - Intrinsic dwarfism presenting at birth. Preliminary communication on nomenclature. PMID- 4198435 TI - Comparison of carbenicillin and penicillin in the treatment of uncomplicated gonorrhea. PMID- 4198436 TI - Current concepts in therapy: general concepts in the use of antibiotics in adults. PMID- 4198437 TI - Nonspecific warm hemolysins of papain-treated cells: serologic characterization and transfusion risk. PMID- 4198438 TI - Autoimmune hemolytic anemia caused by anti-D. PMID- 4198439 TI - Post-Konyne hepatitis: the ineffectiveness of screening for the hepatitis B antigen (HBAg). PMID- 4198440 TI - Another pitfall in blood group testing for nonpaternity. PMID- 4198441 TI - Abortion associated with Brucella abortus (Biotype 1) in the T.B. mare. PMID- 4198443 TI - [Bacteriological studies on wall to wall carpeting. I. Significance of threatened and texture of wall to wall carpeting for the disinfectant]. PMID- 4198442 TI - [Septic gonococcal exanthema]. PMID- 4198444 TI - [Quantitative determination of immunoglobulins in the serum of pregnant women with diabetes mellitus or with Rh antibodies]. PMID- 4198445 TI - [Two cases of subtotal resection of the small intestine after total colectomy. Attempted definition of the smallest remaining intestinal segment necessary for survival]. PMID- 4198446 TI - [Technique and indications of long term parenteral nutrition in the child]. PMID- 4198448 TI - Interrelations between diagnostic criteria of the iron status and 50-mg ferrous iron absorption in iron-replete and iron-deficient subjects. PMID- 4198447 TI - [Surgical aspects of massive resections of the small intestine]. PMID- 4198449 TI - The histochemistry of fibrinolysis in haemophilic synovial membranes. PMID- 4198451 TI - Recombination experiments with an unusual L-chain related myeloma protein. PMID- 4198452 TI - Myeloma in mother and daughter. PMID- 4198450 TI - Ready release of intracellular muramidase (lysozyme) from mononuclear cells in the skin window exudates. PMID- 4198453 TI - Myelofibrosis, osteolytic bone lesions and hypercalcemia in chronic myeloid leukemia. PMID- 4198454 TI - Nitroglycerin and coronary blood flow in coronary artery disease. PMID- 4198455 TI - Use of parenteral nutrition in treatment of advanced regional enteritis. PMID- 4198456 TI - Paresthesias and hypophosphatemia occurring with parenteral alimentation. PMID- 4198457 TI - Hormone and enzyme levels in normal and complicated pregnancy. PMID- 4198458 TI - Localization of human chorionic gonadotropic and somatomammotropic hormones by the peroxidase immunohistoenzymologic method in villi and amniotic epithelium of human placentas (from six weeks to term). PMID- 4198459 TI - Scrub typhus in South Vietnam. A study of 87 cases. PMID- 4198460 TI - The translabyrinthine removal of acoustic and other cerebellopontine angle tumors. PMID- 4198462 TI - Respiratory abnormalities in workers exposed to grain dust. PMID- 4198461 TI - Electrical stimulation of the inner ear. PMID- 4198463 TI - Chronic exposure to nitrogen dioxide. PMID- 4198464 TI - Pressure effect on ERG and optic nerve conduction of visual impulse. Short-term effects in owl monkeys. PMID- 4198466 TI - Kinetics of entry and distribution of 5-fluorouracil in cerebrospinal fluid and brain following intravenous injection in a primate. PMID- 4198465 TI - Unusual intranuclear tubular structures associated with the maturation of Herpesvirus saimiri in monkey kidney cell cultures. AB - Unusual intranuclear tubules have been observed in cultures of both African green monkey and owl monkey kidney cells infected with Herpesvirus saimiri; the material was studied in thin sections with the electron microscope. The tubules were seen in about 10% of virus-containing cells at the stage when the virus matured by budding at the nuclear membrane, measured 160-180 nm in diameter and up to 3.6 MUm in length, were bounded by an outer "membrane" and contained beneath this an electron dense repeating structure arranged either as a coil or a series of evenly spaced rings. The morphology and significance of the tubules are discussed. PMID- 4198468 TI - Immunological progress in bilharziasis. PMID- 4198467 TI - Increase of soluble RNA methylase activities by chemical carcinogens. PMID- 4198469 TI - Evaluation of hollow fiber and spiral coil membrane oxygenators designed for cardiopulmonary bypass in infants. PMID- 4198471 TI - Studies of the distribution of a new avian pancreatic polypeptide and insulin among birds, reptiles, amphibians and mammals. PMID- 4198470 TI - Infective endocarditis in drug addicts. Experiences with medical and surgical treatment. PMID- 4198472 TI - Morphological and functional evidence for corpus luteum activity during late pregnancy in the rhesus monkey. PMID- 4198474 TI - Toxicity of metabolites produced by the "Alternaria". PMID- 4198473 TI - The biological response of infant nonhuman primates to a polychlorinated biphenyl. PMID- 4198475 TI - Protein calorie malnutrition in early childhood. PMID- 4198476 TI - Red cell density in various blood disorders. PMID- 4198477 TI - [Studies on the identification of infection source for pulmonary tuberculosis in a family using bacteriophage types as a marker. 2. Studies on the source of infection in family]. PMID- 4198479 TI - Contributions of army medicine to civilian medicine. PMID- 4198478 TI - Diseases from pets. PMID- 4198480 TI - A study of malaria rates in the Que Son Mountains of Vietnam. PMID- 4198481 TI - Case for diagnosis. PMID- 4198482 TI - Prophylaxis of malaria in man using the sulfone DFD with pyrimethamine. PMID- 4198483 TI - A survey to assess potential human disease hazards along proposed sea level canal routes in Panama and Colombia. IV. Arbovirus surveillance in man. PMID- 4198484 TI - Tuberculosis in active duty military personnel. PMID- 4198485 TI - Clinical decisions and outcomes in a navy psychiatric service. PMID- 4198486 TI - The military pediatric experience as training. PMID- 4198487 TI - In vitro thyroid function tests: a comparison of some commercially available kits. PMID- 4198488 TI - Gonorrhea in a military prenatal population. PMID- 4198489 TI - Beta-hemolytic streptococcus in a population of antepartum patients. PMID- 4198490 TI - [Effectiveness of prophylactic administration of anti-Rh (D) immunoglobulin, based on immunofluorescent and cytochemical methods of fetal hemoglobin determination]. PMID- 4198491 TI - [Brain tumors as a cause of epileptic attacks in children]. PMID- 4198492 TI - [Immunoprophylaxis in serologic incompatibility]. PMID- 4198493 TI - Lennox's syndrome and lead intoxication. PMID- 4198494 TI - Gonococcal arthritis in a newborn infant. PMID- 4198495 TI - Gonococcal tonsillitis-pharyngitis in a 5-year-old girl. PMID- 4198496 TI - Pesticides in soil: organochlorine pesticide residues in soils and crops of the Corn Belt region, United States--1970. PMID- 4198497 TI - [Does fenfluramine mean a real advance in the treatment of obesity?]. PMID- 4198498 TI - An interracial study in the management of infants and children with convulsions. PMID- 4198499 TI - A technique for chronic subclavian vein catheterization. PMID- 4198501 TI - [Use of primidone in symptomatic awakening epilepsies]. PMID- 4198500 TI - Pesticide residues in food. PMID- 4198502 TI - [Epidemiology of the urinary tract infection in patients with prolonged catheterization in an intensive care unit]. PMID- 4198503 TI - Aggression within social groups of rhesus monkeys (Macaca mulatta): effect of contact between groups. PMID- 4198504 TI - Monkeys (Macaca mulatta) raised only with peers. A pilot study. PMID- 4198505 TI - Courtship processing in Drosophila melanogaster. I. Selection for receptivity to wingless males. PMID- 4198506 TI - Courtship processing in Drosophila melanogaster. II. An adaptation to selection for receptivity to wingless males. PMID- 4198507 TI - [Late recurrence of mediastino-pulmonary sarcoidosis treated continyuously with cortisone for 2 years]. PMID- 4198508 TI - Australia antigen in Zaire. Studies on leprosy. PMID- 4198510 TI - [Serological identification of Bacteroides in relation to their pathogenicity]. PMID- 4198511 TI - Additional phage-typing scheme for C. diphtheriae. PMID- 4198509 TI - [Child hypothyroidism due to isolated defect in hypophyseal thyroid stimulating hormone]. PMID- 4198512 TI - [Histopathological study of experimental diphtheria in the guinea pig]. PMID- 4198513 TI - [Anti-plasmatic protein serums. I. Classification of human anti-protein serums]. PMID- 4198515 TI - A lattice structure in water-swollen liver mitochondria. PMID- 4198514 TI - [Characteristics and epidemiological significance of the Pseudomonas aeruginosa strains isolated in Rumania from sporadic cases and nocosomial infections]. PMID- 4198516 TI - Iodoacetamide-induced sensitization of the pancreatic beta-cells to glucose stimulation. AB - At a glucose concentration of 3mm or less, iodoacetamide had no effect on the release of insulin from microdissected pancreatic islets of ob/ob-mice. At higher glucose concentrations, iodoacetamide exerted both an initial stimulatory and a subsequent inhibitory action. When islets were perifused with 1mm-iodoacetamide and 17mm-glucose the inhibitory action predominated after about 15min of transient stimulation. With decreasing concentrations of iodoacetamide the stimulatory phase was gradually prolonged, and with 0.003-0.1mm-iodoacetamide stimulation only was observed for 75min. Prolonged stimulation was also noted after a short pulse of iodoacetamide. Similar responses to 0.1mm-iodoacetamide were observed with islets from normal mice. With islets from ob/ob-mice the effect of 0.1mm-iodoacetamide was reproduced with 0.1mm-iodoacetate, whereas 0.1mm-acetamide had no apparent effect. Iodoacetamide increased the V(max.) of glucose-stimulated insulin release without altering the apparent K(m) for glucose. Leucine, glibenclamide or theophylline could not replace glucose in this synergistic action with iodoacetamide. Iodoacetamide rather inhibited the insulin releasing action of theophylline. Iodoacetamide-induced potentiation of the glucose-stimulated insulin release was rapidly and reversibly inhibited by mannoheptulose, adrenaline, or calcium deficiency. The potentiating effect on insulin release was not paralleled by effects on glucose oxidation or on islet fructose 1,6-diphosphate. However, the inhibitory action of iodoacetamide might be explained by inhibition of glycolysis as evidenced by an inhibition of glucose oxidation and a rise of fructose 1,6-diphosphate. The results support our previous hypothesis that thiol reagents can stimulate insulin release by acting on relatively superficial thiol groups in the beta-cell plasma membrane. Glycolysis seems to be necessary in order for iodoacetamide to stimulate in this way. PMID- 4198517 TI - The purification and properties of extracellular glycosidases of the cellular slime mould Dictyostelium discoideum. AB - The purification of beta-N-acetylhexosaminidase, alpha-glucosidase, alpha mannosidase and beta-glucosidase from the spent growth medium of Dictyostelium discoideum strain Ax-2 myxamoebae is described. beta-N-Acetylhexosaminidase and alpha-glucosidase were obtained in high yield and as homogeneous preparations whereas the alpha-mannosidase preparation consisted of two electrophoretically distinct isoenzymes. The physical, chemical and kinetic properties of these enzymes are described. PMID- 4198518 TI - Bioavailability of peroral dosage forms. PMID- 4198520 TI - [Determination of fat in green olives by indirect complexometry with Mg(II)]. PMID- 4198521 TI - [Determination of fat in raw and roasted almonds and hazelnuts by indirect complexometry with Mg(II)]. PMID- 4198519 TI - [Volumetric determination of the fat content of nuts by indirect complexometry with Mg(II)]. PMID- 4198522 TI - Anatomical differences between the neocortex of man and other primates. PMID- 4198523 TI - Centrifugal fibers to the retina in the rhesus monkey. PMID- 4198524 TI - [Disodium chromoglycate (D. S. C. G.) in the treatment of non-specific chronic bronchopathies. Preliminary results]. PMID- 4198526 TI - Studies of the use of tumor vaccine for the cancer patient. PMID- 4198525 TI - [Melanic ganglioneuroma of the choroid]. PMID- 4198527 TI - Pathophysiology of shock secondary to underwater decompression sickness. PMID- 4198529 TI - Enteral hyperalimentation with elemental diet. PMID- 4198531 TI - [Characteristics of the DNA of Astasia longa and Euglena gracilis phytoflagellates]. PMID- 4198530 TI - [Effect of hormones on the liver and muscle glycogen synthetase activity of lampreys and scorpion fish]. PMID- 4198528 TI - Local metabolic changes in spinal cord injury. PMID- 4198532 TI - Double-antibody solid-phase radioimmunoassays for gonadotropins in serum. PMID- 4198534 TI - The jejunal mucosa in protein-energy malnutrition. A clinical, histological, and ultrastructural study. PMID- 4198533 TI - TRF test in patients with hypothalamic-pituitary disorders. PMID- 4198535 TI - Resynthesis of chick blastodermic cells following dissociation. PMID- 4198536 TI - [Radiotherapy of lung neoplasms]. PMID- 4198537 TI - [Biological implications of the different efficacy of cytostatics in malignant lymphogranuloma]. PMID- 4198540 TI - [Place of Vinca rosea alkaloids (Catharanthus roseus) in the treatment of Hodgkin's disease]. PMID- 4198538 TI - [General considerations on therapeutic strategy in malignant granuloma]. PMID- 4198539 TI - [Intensive therapy of Hodgkin's disease]. PMID- 4198541 TI - [A particularly unusual case of chronic myeloid leukemia]. PMID- 4198542 TI - [Methods of evaluation of spleen sequestration with Cr 51-labeled erythrocytes: proposal for a modified method to make the results more significant]. PMID- 4198543 TI - Production of anti phenobarbital antibody in rabbits by immunization with p azophenobarbital acetylated bovine serum albumin. PMID- 4198544 TI - Circular dichroism studies on protohemoproteins. 3. cytochrome b5 from rabbit liver microsomes, and cytochrome b-557.5 from Rhodospirillum rubrum. PMID- 4198545 TI - The naso-temporal division of the monkey's retina. PMID- 4198546 TI - Pseudomonas pneumonia. PMID- 4198547 TI - A new small diameter mass spectrometer cannula for medical use. PMID- 4198548 TI - Intermediate care for the aged: accommodation requirements and economic considerations. PMID- 4198550 TI - [Criteria of failure in the antibiotic treatment of pulmonary tuberculosis]. PMID- 4198549 TI - [Our experience with pleural biopsic puncture using Castelain's needle]. PMID- 4198551 TI - Urinary tract infection and secretory urinary IgA in malnutrition. PMID- 4198552 TI - Some observations on pelvic floor evolution in primates. PMID- 4198554 TI - [The superior and inferior gluteal nerves in man and in macacus]. PMID- 4198553 TI - Absence of nerve growth factor in the venoms of bees, scorpions, spiders and toads. PMID- 4198555 TI - [The femoral nerve in man and in macacus]. PMID- 4198557 TI - Waldenstrom's macroglobulinaemia with xanthomatosis and hypercholesterolaemia. Report of a case. PMID- 4198556 TI - [Origin of the sacral plexus in man and in macacus]. PMID- 4198558 TI - [Anesthesia of primates (macaca and baboons) under ketamine and neuroleptanalgesia]. PMID- 4198559 TI - The strategy of identification of mycobacteria in a regional reference laboratory. PMID- 4198562 TI - [The classification of mycobacteria]. PMID- 4198560 TI - [Mycobacteria (M. bovis and atypical) identified at the Institut Pasteur, Paris, between 1960 and 1972]. PMID- 4198563 TI - Pathogenicity as the main differentiating character within the avium intracellulare complex. PMID- 4198561 TI - Identification of mycobacteria as a clinical service. PMID- 4198564 TI - Fractionation and purification of the antigenic material for immunogenic studies of atypical mycobacteria. PMID- 4198565 TI - Study of mycobacteria strains belonging to the avian-intracellular group isolated from monkeys. PMID- 4198566 TI - Immunodiffusion analysis--a rational basis for the taxonomy of mycobacteria. PMID- 4198569 TI - [Carbohydrate metabolism in Mycobacterium phlei and Mycobacterium tuberculosis]. PMID- 4198568 TI - Intra-specific variation in the mycobacteria. A taxonomic aid. PMID- 4198567 TI - Thin-layer chromatography of mycobacterial lipids as an aid to classification. PMID- 4198570 TI - [The use of natural substrates as culture media for mycobacteria]. PMID- 4198571 TI - [An inventory of naturally-occurring mycobacteria]. PMID- 4198573 TI - [Jean Lenegre (1904-1972)]. PMID- 4198572 TI - [Aortic insufficiency on a Starr's valve]. PMID- 4198574 TI - [Ist results of a prospective survey on cardiovascular diseases in a large enterprise]. PMID- 4198576 TI - [Anatomo-radiological study of surgical revascularization in myocardial infarction]. PMID- 4198575 TI - [A curious syndrome: atypical complete left bundle branch block and pressure differences on the right ventricle ejection pathway (6 cases)]. PMID- 4198577 TI - [Paradoxical, late and spontaneous reversions of persistent auricular fibrillation]. PMID- 4198578 TI - [Ventricular aneurysms]. PMID- 4198579 TI - [General method for determination of myocardial contractility using data from functional examination]. PMID- 4198580 TI - Ectopic bone formation in patients with spinal cord injury. PMID- 4198581 TI - [Electroencephalographic alterations after administration of vaso-active substance (Hydergine)]. PMID- 4198582 TI - Some properties of the uridine diphosphate glucuronyltransferase activity synthesizing thio-beta-D-glucuronides. AB - 1. Some properties of the UDP-glucuronyltransferase synthesizing thio-beta-d glucuronides were investigated and compared with those of the enzyme synthesizing the O-glucuronides of analogous phenols. 2. Enzyme activity was generally similar for both classes of substrate in tissue distribution, intracellular location, optimum pH, perinatal development and induction by organ culture or by phenobarbital. 3. Certain differences were noted between the two types of activity in behaviour on storage and on activation, in kinetic behaviour and in distribution between Wistar and Gunn rats; the Gunn rats were not deficient in hepatic UDP-glucuronyltransferase activity towards o-aminothiophenol. 4. These differences are no greater than those exhibited in the synthesis of various O glucuronides; therefore thiolic substrates could compete in vivo with phenolic compounds for access to the UDP-glucuronyltransferase complex as well as for UDP glucuronic acid. PMID- 4198583 TI - The characterization of C-phycocyanin from an extremely halo-tolerant blue-green alga, Coccochloris elabens. AB - C-Phycocyanin was isolated and purified from a uni-algal culture of an extremely halo-tolerant blue-green alga, Coccochloris elabens. This alga can be grown under laboratory conditions in 25% (w/v) NaCl. Purified halophile phycocyanin was characterized by amino acid analysis and the measurement of sedimentation velocity, fluorescence polarization and immunodiffusion as a function of protein concentration, pH and ionic strength. The results were compared with those of studies of phycocyanin isolated from Plectonema calothricoides and from several other sources. The states of aggregation previously characterized as being present in other C-phycocyanins, monomer, trimer and hexamer, were present in halophile phycocyanin and were characterized as antigenically related to all C phycocyanins tested. The equilibrium between 3S monomer and 11S hexamer at low concentrations in halophile phycocyanin was quantitatively similar to that for other phycocyanins. The effect of pH and ionic strength on the 6S (trimer) and 11S (hexamer) aggregation of halophile phycocyanin was markedly salt-dependent and the relative amount of each aggregate in the presence of 2m-NaCl was like that of C-phycocyanin from mesophiles, in the absence of additional salt. In antigenic relationship and aggregation properties, the phycocyanin from C. elabens appeared to be most closely related to that isolated from the thermophilic blue-green alga, Synechococcus lividus. Amino acid content of the halophile phycocyanin indicated the presence of a significantly larger number of acidic residues than that found in mesophiles. Explanations of the properties of the halophile protein require consideration of a strong contribution of hydrophobic forces and utilize both charge-shielding and salting-out effects. PMID- 4198584 TI - The organ-specificity of ferritin in human and horse liver and spleen. AB - 1. Ferritin was isolated from human and horse spleen and liver, and apoferritin prepared therefrom. 2. The electrophoretic mobilities of the four apoferritins were determined on polyacrylamide gels and on cellulose acetate strips, and all found to be equal. 3. Homologous ferritins share reactions of identity in immunodiffusion experiments, whereas heterologous ferritins show only partial identity. 4. The subunit molecular weight of each of the apoferritins was determined by polyacrylamide-gel electrophoresis in sodium dodecyl sulphate and by chromatography on agarose columns in 6m-guanidine-HCl. A value of approx. 18500 was found in all cases. The proteins all had sedimentation coefficients of 17-18S. It thus seems that they have identical quaternary structures. 5. The amino acid compositions of the proteins revealed distinct differences both between organs and between species. This was confirmed by analysis of the tryptic peptide patterns, where it was found that about one-third of the peptides were common to the four proteins and the other two-thirds varied from protein to protein. 6. It is concluded that the apoferritins present in the liver and spleen of human and horse are both organ- and species-specific. 7. The apoferritin isolated from the liver of a patient with idiopathic haemochromatosis was identical with normal human liver apoferritin by the criteria described above. PMID- 4198585 TI - Immunological properties of N-acetyl-beta-D-glucosaminidase of normal human liver and of GM2-gangliosidosis liver. AB - Antisera were raised to a partially purified preparation of human liver hexosaminidase and to highly purified preparations of hexosaminidase isoenzymes A and B. All the antisera precipitated the enzyme in an enzymically active form, which could be located on immunodiffusion and immunoelectrophoretic gels by using a histochemical substrate. The antisera to the purified isoenzymes were shown to react with hexosaminidase from human liver, kidney, brain and spleen, but did not cross-react with human liver beta-glucosidase, beta-galactosidase, alpha mannosidase, beta-xylosidase, arylsulphatase or acid phosphatase. Hexosaminidases A and B were immunologically identical. The immunological properties of the hexosaminidases from livers of patients with three types of GM(2)-gangliosidoses were closely similar. No evidence could be found for cross-reacting material in enzyme-deficient states. PMID- 4198586 TI - Two cases of Hunter's syndrome--the anaesthetic and operative difficulties in oral surgery. PMID- 4198587 TI - The inhibitory effect of manganese on transmitter release at the neuromuscular junction of the toad. AB - 1. Manganese, at low concentrations (0.5-2.0 mM), blocks neuromuscular transmission in toads. Endplate potentials (e.p.ps) are reduced in amplitude but the amplitude of miniature endplate potentials (m.e.p.ps) is, if anything, increased.2. The release of transmitter by an action potential is reduced in solutions containing Mn, but is still well described by the Poisson equation.3. Log-log plots of e.p.p. quantal content (m) against [Ca] have a mean gradient of 3.73, and a model based on the co-operative action of four calcium ions in excitation-secretion coupling, and competitive inhibition by Mn, was constructed. The model, with its exponent of 4, is shown in fact to predict gradients of less than four for log-log plots of m against [Ca].4. The assumption of competitive inhibition by Mn was supported by modified Lineweaver-Burk plots of m(-(1/4)) against 1/[Ca]. The mean dissociation constants for Ca and Mn were 1.3 mM and 0.15 mM respectively. From the model, an upper estimate of the density of calcium ;receptor sites' of 30 per square micron of nerve terminal was obtained.5. In contrast to its inhibitory effect on evoked release, Mn increases the spontaneous release of transmitter. It is suggested that Mn may increase m.e.p.p. frequency by releasing Ca from an intracellular store. PMID- 4198588 TI - Glial fibrillary acidic protein from normal human brain. Purification and properties. PMID- 4198589 TI - Influence of sleep-waking and nociceptor-induced behavior on the activity of supraoptic neurons in the hypothalamus of the monkey. PMID- 4198590 TI - Osmosensitivity of hypothalamic magnocellular neuroendocrine cells to intracarotid hypertonic D-glucose in the waking monkey. PMID- 4198592 TI - Supraependymal cells: light and transmission electron microscopy extends scanning electron microscopic demonstration. PMID- 4198591 TI - On perivascular astrocytic membrane specializations in monkey optic nerve. PMID- 4198593 TI - A clinical and microbiological study of venous catheterization. AB - In a prospective study of 210 intravenous catheters and needles 31 (15%) swabs yielded 34 microbial isolates. Twenty-eight were "non-pathogenic" skin commensals and six were "pathogenic" organisms. Commensals were isolated predominantly from catheters left in situ for only a short time (up to two days) and pathogenic organisms most frequently from specimens left in situ for a longer time. Correlation was not confirmed between colonization and infection, antibiotic therapy or phlebitis. All samples of IV fluids were sterile on culture. Changing the IV catheter at least every two days is recommended. PMID- 4198594 TI - Pediatric antimicrobial therapy. II. PMID- 4198596 TI - [Pi system. II. Experiences with the examination of alpha-antitrypsinemia in children]. PMID- 4198595 TI - Listeria monocytogenes infections in Canada. AB - Between 1951 and January 1972 listeriosis was diagnosed bacteriologically in 101 Canadian patients. This study adds 80 cases to the 21 reported from Metropolitan Toronto by Sepp and Roy in 1963. The Laboratory Centre for Disease Control, Ottawa, collated epidemiological and clinical data. Serotypes of Listeria monocytogenes included 4b (53), 1 (15), 1b (6), 1a (2), 2 and 3. Clinically, 54 patients had meningitis and 23 septicemia. The mortality rate was 30%.Between 1954 and January 1972 listeriosis affected 15 British Columbian patients: nine were male and six female; 12 were less than 1 or more than 45 years old. Among the patients were a pregnant mother and the son to whom she gave premature birth. A day-old infant and an elderly man died. PMID- 4198597 TI - Molecular interactions in the phenomenology of the onset of mental illness. PMID- 4198599 TI - Radiosensitivity of oocytes of Drosophila. 3. Sensitivity of class-B oocytes of XX-O and X-X females. PMID- 4198598 TI - [Inhibition of ribulosediphosphate carboxylase by adenosine triphosphate in autotrophic organisms]. PMID- 4198600 TI - [Photochemical activity of phycocyanine and phycoerythrin]. PMID- 4198601 TI - Incidence of signs and symptoms in thyroid disease. PMID- 4198602 TI - [Blood supply of the spinal ganglion]. PMID- 4198603 TI - Effect of mycorrhizal infection on nitrogen and phosphorus nutrition of ericaceous plants. PMID- 4198604 TI - Tetracycline interference with the bactericidal effect of serum. PMID- 4198605 TI - Effect of centrifugation on cell adhesion. PMID- 4198606 TI - Effects of tiger snake venom on the ultrastructure of motor nerve terminals. PMID- 4198607 TI - Serum transferrin levels and the assessment of protein nutritional status. PMID- 4198608 TI - [Simultaneous isoimmunization of pregnant women against Rh and HL-A antigens]. PMID- 4198609 TI - Long term treatment of diabetes mellitus with glibornuride. A new hypoglycemic agent. PMID- 4198610 TI - [Effect of thio-tepa on the microbial flora of the urine in bladder neoplasms]. PMID- 4198611 TI - [Tubular structures in cisterns of ergastoplasm of glial cells in cerebellar cortex of (Macaca cynomolgus)]. PMID- 4198612 TI - A method for obtaining biochemical and biophysical measurements from rhesus monkey fetuses for prolonged periods. PMID- 4198613 TI - Relationship between 3H-ryanodine uptake and myocardial contractility. PMID- 4198614 TI - Avian thrombocyte aggregation and shape change in vitro. PMID- 4198615 TI - Immune hemolytic transfusion reactions in monkeys: activation of the kallikrein system. PMID- 4198616 TI - Specific antilymphocyte antibody for use in renal transplantation. PMID- 4198617 TI - A constant bile duct anomaly encountered during biliary operation. PMID- 4198618 TI - Malaria studies in vitro. II. The measurement of drug activities using leucocyte free blood-dilution cultures of Plasmodium berghei and 3H-leucine. PMID- 4198619 TI - The isolation from human parotid saliva and partial characterization of the protein core of a major parotid glycoprotein. PMID- 4198620 TI - Autonomic innervation of the salivary glands in the marmoset (Callithrix penicillata Jordani); with some gross anatomical and histological observations. PMID- 4198621 TI - Studies on the interaction between rabbit liver pyruvate kinase and its allosteric effector fructose 1,6-diphosphate. AB - Preparation of the L form of rabbit liver pyruvate kinase (EC 2.7.1.40) in the presence of fructose 1,6-diphosphate yielded an enzyme which was kinetically identical with the M or muscle-type form of pyruvate kinase found in liver. Chromatographic and dialysis studies of this complex showed that most of the fructose 1,6-diphosphate molecules were loosely bound to the enzyme, but dilution dissociation studies and binding experiments established that there was a high initial affinity between the enzyme and fructose 1,6-diphosphate (K(assoc.)=2.3x10(9)), and that binding of the loosely bound fructose 1,6 diphosphate was concentration-dependent and a necessary condition to overcome the co-operative interaction observed with the homotropic effector phosphoenolpyruvate. Preparation of the liver enzyme in the absence of EDTA did not yield a predominantly M form of the enzyme, and incubation of the M form in the presence of EDTA did not convert it into the L form, but resulted in inhibition of enzyme activity. Immunological studies confirmed that the L and M forms in liver were distinct, and that preparation of the L form in the presence of fructose 1,6-diphosphate did not produce an enzyme antigenically different from the L form prepared in the absence of this heterotropic effector. PMID- 4198622 TI - Investigations of the structural function of the J chain in human immunoglobulin M. AB - Human IgM molecules were treated with Na(2)SO(3) or mercaptoethylamine in concentrations ranging from 2 to 14mm or 2 to 22mm respectively. The dissociation of IgM to IgM(s) varied from 0% to 100%. At the intermediate concentrations of either reagent the amount of freed J chains was less than expected. In an attempt to find an explanation for this, IgM was partially dissociated to IgM(s) with mercaptoethylamine. The IgM(s) isolated by gel filtration was divided according to the ascending and descending portions of the elution curve. These portions were treated with 24mm-mercaptoethylamine and analysed for the presence of J chains. Only the ascending portion contained free J chains. Thus, after mild reduction where not all the IgM molecules are dissociated to IgM(s), some J chains remain covalently attached to some IgM(s) molecules although most of the J chains are freed. It was concluded that the J chain could serve as a ;hitch' for IgM(s) molecules forming intact IgM. PMID- 4198623 TI - Inhibition by alpha-macroglobulin and other serum proteins. AB - 1. Normal human serum was found to inhibit human cathepsin B1. 2. The major inhibitor present in serum was purified and identified as alpha(2)-macroglobulin. 3. alpha(2)-Macroglobulin was found to bind cathepsin B1 in an approximately 1:1 molar ratio. When bound, the enzyme retained about 50% of its proteolytic activity, and up to 80% of its activity against alpha-N-benzoyl-dl-arginine 2 naphthylamide. 4. Pretreatment of alpha(2)-macroglobulin with cathepsin B1 inactivated by exposure to pH8.5 or iodoacetic acid, in large molar excess, did not prevent the subsequent binding of active enzyme. Active enzyme, once bound, was not protected from inhibition by 1-chloro-4-phenyl-3-tosylamido-l-butan-2 one. 5. Cathepsin B1 was also inhibited by human immunoglobulin G, at high concentration. 6. Because it had been suggested that haptoglobin is responsible for the inhibition of ;cathepsin B' by serum, a method was devised for the selective removal of haptoglobin from mixtures of serum proteins by adsorption on haemoglobin covalently linked to Sepharose. No evidence was obtained that haptoglobin has any inhibitory activity against the enzyme. PMID- 4198624 TI - Purification and characterization of two fructose diphosphate aldolases from Escherichia coli (Crookes' strain). AB - Two fructose diphosphate aldolases (EC 4.1.2.13) were detected in extracts of Escherichia coli (Crookes' strain) grown on pyruvate or lactate. The two enzymes can be resolved by chromatography on DEAE-cellulose at pH7.5, or by gel filtration on Sephadex G-200, and both have been obtained in a pure state. One is a typical bacterial aldolase (class II) in that it is strongly inhibited by metal chelating agents and is reactivated by bivalent metal ions, e.g. Ca(2+), Zn(2+). It is a dimer with a molecular weight of approx. 70000, and the K(m) value for fructose diphosphate is about 0.85mm. The other aldolase is not dependent on metal ions for its activity, but is inhibited by reduction with NaBH(4) in the presence of substrate. The K(m) value for fructose diphosphate is about 20mum (although the Lineweaver-Burk plot is not linear) and the enzyme is probably a tetramer with molecular weight approx. 140000. It has been crystallized. On the basis of these properties it is tentatively assigned to class I. The appearance of a class I aldolase in bacteria was unexpected, and its synthesis in E. coli is apparently favoured by conditions of gluconeogenesis. Only aldolase of class II was found in E. coli that had been grown on glucose. The significance of these results for the evolution of fructose diphosphate aldolases is briefly discussed. PMID- 4198625 TI - Species variations in the O-methylation of n-butyl 4-hydroxy-3,5-diiodobenzoate. PMID- 4198626 TI - [Tracheobronchopathia chondro-osteoplastica]. PMID- 4198627 TI - [Chromatographic analysis of DNA attached to E. coli membranes]. PMID- 4198628 TI - [Study in Rayleigh diffusion of DNP and RNP in hepatocyte nuclei]. PMID- 4198629 TI - [Role of the phosphate carrier in oxidative phosphorylation]. PMID- 4198630 TI - [Bacterial formation and degradation of a nitrosamine, paranitrosodimethylaniline]. PMID- 4198631 TI - [Ultrastructural study of lesions specifically induced by T anti-autoantigen autoantibody on guinea pig epididymal spermatozoa]. PMID- 4198632 TI - [Study of precipitogens of equine infectious anemia virus]. PMID- 4198633 TI - Radiographic studies of amyloidosis. PMID- 4198634 TI - Plasmodium spp.: dispersion of malarial oocyst populations in anopheline and culicine mosquitoes. PMID- 4198635 TI - Humoral antibody response and Ig characterization of the specific agglutinins in rabbits during experimental American trypanosomiasis. PMID- 4198636 TI - Computerized microacidimetric determination of beta lactamase Michaelis-Menten constants. PMID- 4198637 TI - [2 years of "early" rehabilitation following myocardial infarct at the clinic Hohenried. 1. Definition and problems of "additional treatment procedures"]. PMID- 4198638 TI - [Psychotherapeutic possibilities and psycho-social rehabilitation methods for patients with chronic kidney diseases in the permanent dialysis program]. PMID- 4198639 TI - Binding of thyroid hormones to a soluble fraction from porcine anterior pituitary. PMID- 4198640 TI - Growth of pseudomonas species on phenylacetamide. PMID- 4198641 TI - Ultrastructural development of Nostoc muscorum A. PMID- 4198642 TI - Unbalanced growth and replication of chloroplast populations in Euglena gracilis. PMID- 4198643 TI - The isolation of tyrosinase from Aspergillus nidulans, its kinetic and molecular properties and some consideration of its activity in vivo. PMID- 4198644 TI - Inactivation of southern bean mosaic virus and its ribonucleic acid by nitrous acid and ultraviolet light. PMID- 4198645 TI - Superficial venous arrangement of the face and neck of the tufted capuchin, Cebus apella Linnaeus, 1758. PMID- 4198646 TI - Studies on human malaria in Aotus monkeys. I. Sporozoite transmission of Plasmodium vivax from El Salvador. PMID- 4198647 TI - Studies on human malaria in Aotus monkeys. II. Establishment of a strain of Plasmodium falciparum from Panama. PMID- 4198648 TI - The 2-mercaptoethanol labile immunoglobulin response of beagles experimentally infected with Dirofilaria immitis. PMID- 4198649 TI - Demodectic mites of subhuman primates I: Demodex saimiri sp. n. (Acari: Demodicidae) from the squirrel monkey, Saimiri sciureus. PMID- 4198650 TI - A simple method for the detection of human congenital Chagas' disease. PMID- 4198651 TI - Ultrastructural changes in Babesia argentina-infected erythrocytes in kidney capillaries. PMID- 4198652 TI - Haemogregarina platessae Lebailly (=H. achiri Saunders) from the Hogchoker in Maryland. PMID- 4198653 TI - [Therapeutic action of nitroglycerine]. PMID- 4198654 TI - [Disodium chromoglycate in the treatment of occupational asthma due to fluor hypersensitivity]. PMID- 4198655 TI - Economic class and use of physician services. PMID- 4198656 TI - The sources of hospital infection. PMID- 4198657 TI - Immunity to brucella infection. PMID- 4198658 TI - East Coast fever: correlation between the morphology and infectivity of Theileria parva developing in its tick vector. PMID- 4198659 TI - Sound spectral properties of conditioned vocalization in monkeys. PMID- 4198660 TI - Biological versatility and earth history. AB - Examples from various plant and animal groups indicate that there has been a general increase in potential versatility of form, determined by the number and range of independently varying morphogenetic parameters, among taxa appearing at successively younger stages in the fossil record. Taxa or body plans with higher potential versatility have tended to replace less potentially versatile groups in the same or similar adaptive zone through time. Greater potential diversity allows for greater homeostasis, efficiency, and integration of structures and functions, and for an increase in size of the potential adaptive zone. In contrast, chemical versatility has generally decreased within groups from the pre Cambrian to the Phanerozoic, partly as the result of apparent changes in the chemical environment and partly as the consequence of selection for efficiency and greater metabolic ease of handling of certain materials. PMID- 4198661 TI - Crossing-over between X AND Y chromosomes during ribosomal DNA magnification in Drosophila melanogaster. AB - In genetic combinations undergoing ribosomal DNA magnification, the frequency of crossing-over between X and Y chromosomes is increased at least 20-fold above that in similar combinations not undergoing magnification. Such recombination occurs at the ribosomal DNA level. The data are consistent with a model where extra copies of ribosomal DNA are formed which, after circularization, are integrated into the chromosome. PMID- 4198662 TI - Carbon dioxide hydration activity of carbonic anhydrase: paradoxical consequences of the unusually rapid catalysis. AB - The kinetic parameters for carbon dioxide hydration catalysis by carbonic anhydrase (EC 4.2.1.1) present an apparent paradox. The assumption of H(2)CO(3) as the hydration product requires the rate of recombination of H(2)CO(3) with enzyme to be faster than the diffusion limit. The alternative assumption of HCO(3) (-) as the product of hydration likewise requires active-site ionization rates to exceed the diffusion limit. We previously postulated the presence of special means for rapid active-site ionization. It is shown here that when proton transfer between enzyme and buffer species is taken into account, there is no need to invoke rates exceeding the diffusion limit. Bicarbonate ion thus appears as the most probable hydration product and dehydration substrate. PMID- 4198664 TI - The mental hospital as an institution. PMID- 4198665 TI - The impact of waterborne diseases on mortality. PMID- 4198663 TI - Segregation during ascidian embryogenesis of egg cytoplasmic information for tissue-specific enzyme development. AB - Cleavage-arrested embryos of the ascidian Ciona intestinalis were able to differentiate two tissue-specific enzymes-muscle acetylcholinesterase (EC 3.1.1.7) and brain pigment cell tyrosinase (EC 1.10.3.1). Cytochalasin B, colchicine, Colcemid, and podophyllotoxin were used as cleavage inhibitors at early embryonic stages up to the 64-cell stage. Only certain cells in the cleavage-arrested embryos developed these histochemically detectable enzymes, and this ability followed the cell lineage patterns for the two tissues. This result implies the presence of specific positional information in the egg cytoplasm that is differentially segregated during cleavage. There were distinct and separate puromycin and actinomycin D sensitivity periods for the occurrence of each enzyme during development of both normal and cleavage-arrested embryos. The segregated information is apparently neither the enzyme proteins nor RNA templates for enzyme synthesis, but is probably concerned with activation of appropriate genes. PMID- 4198666 TI - The influence of fluid shear on the kinetics of blood coagulation reactions. PMID- 4198667 TI - Validation and bioengineering aspects of an implantable glucose sensor. PMID- 4198668 TI - Bio-artificial liver: a combined system of hemodialysis and baboon liver perfusion. PMID- 4198669 TI - Morphologic studies of dialysis membranes adherence of blood components to air rinsed coils. PMID- 4198670 TI - Membrane lung oxygenation for temporary support of the failing transplanted lung. PMID- 4198672 TI - An outbreak of anthrax at the Chester Zoological Gardens. PMID- 4198671 TI - The surface bonded, covalently crosslinked urokinase synthetic surface. In vitro and chronic in vivo studies. PMID- 4198673 TI - Immunological relationship between border disease, mucosal disease and swine fever. PMID- 4198674 TI - Human and macaque blue cones studied with electroretinography. PMID- 4198676 TI - [Carcinogen-binding protein in normal and tumorous cells]. PMID- 4198675 TI - [Use of thermal effects in the compound treatment of malignant tumors]. PMID- 4198677 TI - [Characteristics of the regulation of glycolysis at various stages of carcinogenesis in the liver]. PMID- 4198679 TI - Secondary stimulation of Rh antibodies by kidney allografts from Rh-positive donors. PMID- 4198678 TI - Persistent mixed field polyagglutinability. An immunofluorescence study in genetically abnormal red cells. PMID- 4198680 TI - A new blood group antigen, Hov. PMID- 4198681 TI - Rhesus blood group notations. PMID- 4198682 TI - A service-integrated approach to clinical pharmacy practice through a hyperalimentation program. PMID- 4198683 TI - Pseudomonas pneumonia. A retrospective study of 36 cases. PMID- 4198684 TI - Antimicrobial activity of tobramycin and gentamicin used in combination with cephalothin and carbenicillin. PMID- 4198685 TI - Pollutant burdens and biological response. PMID- 4198686 TI - Carbon monoxide inhalation effects following myocardial infarction in monkeys. PMID- 4198687 TI - Antitrypsin deficiency and abnormal protease inhibitor phenotypes. PMID- 4198688 TI - Measles giant cell pneumonia in an adult following long-term chemotherapy. PMID- 4198689 TI - Comparison of antigenicity of rat collagen prepared by various methods. PMID- 4198691 TI - Studies on the epizootiology of bovine babesiosis in common border areas of New South Wales and Queensland. PMID- 4198690 TI - Studies on the epizootiology of bovine babesiosis in north eastern New South Wales. PMID- 4198693 TI - [Individualization of a preleptotene stage of chromosomal condensation in the rabbit ovocyte]. PMID- 4198692 TI - Inhibition of prostaglandin biosynthesis by 7-oxa- and 5-oxa-prostaglandin analogues. AB - Some oxaprostaglandin derivatives have been shown to inhibit prostaglandin biosynthesis from arachidonate by a particulate prostaglandin synthetase preparation. The most potent inhibitor was 5-oxaprost-13-trans-enoate, and inhibition by this compound appeared to be competitive. Certain structure activity relationships were ascertained. PMID- 4198694 TI - [Anatomo-clinical, immuno-pathological and ultrastructural study of 16 glomerular nephropathies in an inter-tropical zone (preliminary results)]. PMID- 4198696 TI - [Genesis of primary abnormalities of the optic vesicle caused by cyclophosphamide in rabbit embryos]. PMID- 4198695 TI - [Demonstration and study of the action of a mycotoxin, beauvericine, on insect cells cultured in vitro]. PMID- 4198697 TI - [Method of trial of antihypertensive agents in cynocephalic monkeys]. PMID- 4198698 TI - Lung function after mantle field irradiation in Hodgkin's disease. PMID- 4198699 TI - Role of radiotherapy in the treatment of cancer of the tongue. A retrospective analysis on TNM-staged tumors treated between 1958 and 1968. PMID- 4198700 TI - Peripheral nerve tumors with rhabdomyosarcomatous differentiation (malignant "Triton" tumors). PMID- 4198701 TI - Regional blood flows in unanaesthetized rhesus monkeys during myocardial infarction. PMID- 4198702 TI - Ankle arthrography in acute sprains. PMID- 4198703 TI - Effects of immune environments upon bone in vitro. I. Cytotoxicity of antibodies to bone homogenates. PMID- 4198704 TI - Experimental scoliosis. PMID- 4198705 TI - [Release of mRNA in the form of mRNP in the dissociation of polyribosomes by polyvinylsulfate and puromycin]. PMID- 4198707 TI - Constant oxygen enhancement ratio during the mitotic cell cycle in x-rayed Drosophila melanogaster embryos. PMID- 4198706 TI - A novel monoquaternary neuromuscular blocking agent. PMID- 4198709 TI - [Lack of correlation between serotype and lysotype of Pseudomonas aeruginosa]. PMID- 4198708 TI - [Potentiation by EDTA and levallorphan of the effect of sulfamethoxazole trimethoprim on Escherichia coli]. PMID- 4198711 TI - The use of antibiotics in hospital. PMID- 4198710 TI - Studies on rabbit secretory and serum antibodies to hog intrinsic factor. PMID- 4198712 TI - Correlation between PaCO2 and regional cerebral blood volume by x-ray fluorescence. PMID- 4198713 TI - The properties of virginiamycin-resistant mutants of Bacillus subtilis. PMID- 4198714 TI - The use of polyacrylamide gel electrophoresis in taxonomy of Brucella. PMID- 4198715 TI - Penicillin production by lysine auxotrophs of Penicillium chrysogenum. PMID- 4198716 TI - Subunit structure of cholera toxin. PMID- 4198717 TI - A bacitracin-negative mutant of Bacillus licheniformis which is able to sporulate. PMID- 4198718 TI - Mutants of Pseudomonas aeruginosa with impaired -lactamase inducibility and increased sensitivity to -lactam antibiotics. PMID- 4198719 TI - Cloxacillin and nafcillin: serum binding and its relationship to antibacterial effect in mice. PMID- 4198720 TI - Nutritional profiles of Neisseria gonorrhoeae, Neisseria meningitidis, and Neisseria lactamica in chemically defined media and the use of growth requirements for gonococcal typing. PMID- 4198721 TI - The silvered leaf-monkey of Malaysia, Presbytis cristatus: disease model for human scrub typhus. PMID- 4198722 TI - Experimental gingivitis in Macaca speciosa monkeys: clinical, bacteriologic and histologic similarities to human gingivitis. PMID- 4198723 TI - Posttraumatic transient cerebral blindness. Association with migraine and seizure diatheses. PMID- 4198724 TI - Serological typing of Pseudomonas aerginosa from mouse breeding colonies. PMID- 4198726 TI - Changes in serotype of Pseudomonas aeruginosa. PMID- 4198725 TI - Passive hemagglutination reaction using formalinized sheep erythrocytes treated with tannin and coated with protein moiety of the endotoxin (OEP) of Pseudomonas aeruginosa. PMID- 4198727 TI - Micellar structure and endotoxic activities of gram-negative lipopolysaccharides. PMID- 4198728 TI - Characterization of anti-cord factor antibody. PMID- 4198729 TI - Regulation of staphylococcal enterotoxin B synthesis and its relation to other extracellular proteins. PMID- 4198730 TI - Some properties of the diphtheria toxin fragment produced by a beta phage-mutant lysogen of Corynebacterium diphtheriae. PMID- 4198731 TI - Methylation of basic residues in structural proteins. PMID- 4198732 TI - [Investigations of effective duration of disodium cromoglycate (DSCG) in extrinsic allergic asthma bronchiale]. PMID- 4198733 TI - [Treatment of bronchial asthma in childhood with disodium cromoglycate]. PMID- 4198734 TI - Serial reversal learning by monkeys with inferotemporal or foveal prestriate lesions. PMID- 4198735 TI - Diurnal variation of ileum motility in monkey during different feeding and avoidance-conditioning schedules. PMID- 4198736 TI - Hypothalamic "coding" in the unanesthetized monkey of noradrenergic sites mediating feeding and thermoregulation. PMID- 4198737 TI - Premotor cortex and instrumental behavior in monkeys. PMID- 4198738 TI - Brain mechanisms in movement. PMID- 4198739 TI - Effect of the bee venom and melittin on plasma cortisol in the unanesthetized monkey. PMID- 4198740 TI - Estrogenic effect in vaginal smears in cases of carcinoma in situ and microinvasive carcinoma of the uterine cervix. PMID- 4198741 TI - [Bilateral ossification of the stylohyoid ligament]. PMID- 4198742 TI - Absorption from mucosal surfaces. PMID- 4198744 TI - [Transplantation in a system of complex treatment of habitually aborted pregnancy]. PMID- 4198743 TI - The stimulation of eccrine sweating by pharmacologic agents. PMID- 4198745 TI - When to use two or more antibiotics. PMID- 4198746 TI - Penicillin phenoxymethyl. Use in rheumatic fever prophylaxis. PMID- 4198747 TI - Stickler syndrome in a pedigree of Pierre Robin syndrome. PMID- 4198748 TI - Non-atheromatous stenosis and occlusion of the internal carotid artery and its main branches. PMID- 4198749 TI - Angiographic evidence for cerebral (opercular) swelling in patients with seizures. PMID- 4198750 TI - Tuberculoma of the brain (revisited). PMID- 4198751 TI - [Practical value of radioimmunoassay of pituitary thyreotropic hormone]. PMID- 4198752 TI - Inhibition by L-triiodothyronine and dexamethasone of TSH response to thyrotropin releasing hormone in man. PMID- 4198753 TI - [Pituitary reactivity to thyrotropin releasing hormone (TRH) in patients with hyperthyroidism considered as clinically cured]. PMID- 4198754 TI - [Role of prealbumin in physiological transport of thyroxine]. PMID- 4198755 TI - Evaluation of a free thyroxine index. PMID- 4198756 TI - Comparison of precipitation malarial antibodies produced by indigenous immune Gambians and an infected European. PMID- 4198757 TI - [Bacterial pollution of the seawater along the Belgian coast]. PMID- 4198758 TI - Beta-ketothiolase from Hydrogenomonas eutropha H16 and its significance in the regulation of poly-beta-hydroxybutyrate metabolism. AB - 1. beta-Ketothiolase was purified 49-fold from fructose-grown cells of Hydrogenomonas eutropha H16 with a yield of 27%; the purification procedure involved precipitation by cetyltrimethylammonium bromide, DEAE-cellulose chromatography and exclusion chromatography on Sephadex G-200; the freeze-dried enzyme is stable. The molecular weight determined by sucrose-gradient centrifugation (8.2S) and by gel filtration is 147000-150000. The optimum pH for the cleavage reaction is 8.1, that for the condensation reaction 7.8, both measured in Tris-HCl buffer. 2. The kinetics of the cleavage reaction are described. Substrate-saturation curves were measured with both acetoacetyl-CoA and CoA as the variable substrates. The concentration of the second substrate was kept constant and was varied during successive experiments. The cleavage reaction is characterized by substrate inhibition by acetoacetyl-CoA, which is partially relieved by free CoA. Hill plots indicate two acetoacetyl-CoA-binding sites. 3. The substrate(acetyl-CoA)-saturation curve for the condensation reaction is hyperbolic. The K(m) was 3.9x10(-4)m-acetyl-CoA. In the presence of CoA sigmoidal curves were obtained, with an increasing sigmoidicity from 0.03 to 0.30mm-CoA. The inhibitory action of CoA on the beta-ketothiolase condensation reaction and its possible involvement in the regulation of poly-beta-hydroxybutyrate synthesis and degradation are discussed. PMID- 4198759 TI - Lethal effect of rifampicin in Bacillus subtilis as a complicating factor in the assessment of the lifetime of messenger ribonucleic acid. AB - The bactericidal action of rifampicin was compared with that of chloramphenicol in growing and in sporulating cultures of Bacillus subtilis 168. Chloramphenicol kills cells only very slowly, but exposure to rifampicin kills over 95% of cells in a few minutes, causing gross physical damage, which is visible in both phase contrast and electron microscopy. This is accompanied by a fall in O(2) consumption and by lysis. Experiments with synchronized cultures showed that susceptibility to the lethal effect of rifampicin is greater when the cells are dividing. The results suggest that the synthesis of some species of RNA other than mRNA may be necessary for the maintenance of cell integrity, although experiments with actinomycin D do not altogether fit this interpretation. However, we conclude that rifampicin is too toxic to use as an antibiotic for assessing the lifetime of mRNA. PMID- 4198761 TI - Properties of tRNAPhe from Drosophila. PMID- 4198760 TI - Control of the production of exo-beta-N-acetylglucosaminidase by Bacillus subtilis B. AB - 1. The control of exo-beta-N-acetylglucosaminidase (EC 3.2.1.30) production by Bacillus subtilis B growing on a chemically defined medium was studied. 2. The enzyme was repressed during exponential growth by those carbon sources that enter the glycolytic pathway above the level of phosphoenolpyruvate. When exponential growth ceased as a result of low concentrations of the nitrogen, carbon or metal ion components of the medium, the enzyme was formed and its amount could be increased by the addition of cell-wall fragments as inducer. 3. The enzyme was de repressed and could be induced during exponential growth on non-glycolytic compounds metabolized directly into pyruvate, acetyl-CoA or tricarboxylic acid cycle intermediates. 4. The major difference in the metabolism of the organism utilizing these two groups of compound was the existence of high activities of phosphoenolpyruvate carboxylase required for gluconeogenesis. 5. It is concluded that the de-repression of glucosaminidase occurs when the only principal change detected in the intermediary metabolism of the organism was the presence of high activities of phosphoenolpyruvate carboxylase. 6. When the organism was grown on media containing repressing compounds, the enzyme was only de-repressed on entry of the cells into the initial stages of sporulation, where phosphoenolpyruvate carboxylase activity, even in the presence of excess of glucose, increased in parallel with glucosaminidase, neutral proteinase and alkaline phosphatase activities. 7. These results suggest a strong link, at the level of the tricarboxylic acid cycle, between the control of phosphoenolpyruvate carboxylase and the control of the de-repression of glucosaminidase and sporulation. PMID- 4198762 TI - Association of a ribonuclease with the 50-S ribosomal subunit of Escherichia coli MRE 600. PMID- 4198764 TI - Physical characterization of alpha-amylase inhibitors from wheat. PMID- 4198763 TI - Protein synthesis by rat cardiac muscle myofibrils. PMID- 4198765 TI - Bovine intestinal calcium-binding proteins. Purification and some properties. PMID- 4198766 TI - The myoglobin of primates. 4. New World monkeys: Cebidae: (1) Saimiri sciureus (squirrel monkey); (2) Lagothrix lagothricha (Humboldt's woolly monkey). Callitrichidae: Callithrix jacchus (common marmoset). PMID- 4198767 TI - Snake venom toxins the amino acid sequences of two toxins from Ophiophagus hannah (King cobra) venom. PMID- 4198769 TI - Changes in glomerular filtration rate during long-term treatment with propranolol in patients with arterial hypertension. PMID- 4198768 TI - Pharmacokinetic study of a patient with diphenylhydantoin toxicity. PMID- 4198770 TI - Clinical applications of thyrotrophin-releasing hormone. PMID- 4198771 TI - The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat. PMID- 4198772 TI - CI-750, A novel antidiarrheal agent. PMID- 4198773 TI - Comparable behavior maintained under fixed-ratio and second-order schedules of food presentation, cocaine injection or d-amphetamine injection in the squirrel monkey. PMID- 4198774 TI - The effects of verapamil on metabolism and contractility of the toad skeletal muscle. PMID- 4198775 TI - [Venacorn in the treatment of varicose leg ulcer]. PMID- 4198776 TI - [Anomaly of the maxillodental system in monkeys]. PMID- 4198777 TI - Transgastric jejunal intubation. PMID- 4198778 TI - [Effect of complex therapy (including antienzymes) on the trace element composition of the blood of patients with chronic pancreatitis]. PMID- 4198779 TI - Effect of intravenous polyunsaturated phosphatidyl choline in experimental atherosclerosis. PMID- 4198780 TI - [Insulin secretion after oral and intravenous administration of various 1st and 2d generation sulfonylurea derivatives in equipotential dosage]. PMID- 4198781 TI - [Betacytotropic and antilipolytic effect of critical doses of tolbutamide and glibenclamide]. PMID- 4198782 TI - [Intravenous fat tolerance test--simple modification and results following ethanol load]. PMID- 4198784 TI - [Preservation of bone marrow]. PMID- 4198783 TI - [Behavior of serum retinol-binding-protein in hepatitis]. PMID- 4198785 TI - [Nutrition disorders in mesenteric arterial occlusions and their therapy]. PMID- 4198786 TI - [Serology and biochemistry of erythrocyte antigens corresponding to cold autoantibodies]. PMID- 4198787 TI - [Immunological studies in patients with arteriosclerosis]. PMID- 4198788 TI - [Circulating plaque forming cells after Rhesus sensitization]. PMID- 4198789 TI - Histochemical distribution of phosphorylase in the central nervous system of primates, Saimiri sciureus and Macaca mulatta. PMID- 4198790 TI - Surface ultrastructure of reproductive tract in female crab-eating (M. fascicularis) and bonnet (M. radiata) macaques. PMID- 4198791 TI - Lateral hypothalamic nuclei in the macaque (Macaca mulatta) brain: myeloarchitectonics. PMID- 4198792 TI - [I. Transferrin determination by radial immunodiffusion, comparison with a chemical method of TIBC determination]. PMID- 4198793 TI - [Technic of specific determination of plasma proteins by radial immunodiffusion applied to mass screening]. PMID- 4198794 TI - [A study of the production of anti-tyrosinase antibodies in rabbits. I. Cellular studies]. PMID- 4198795 TI - [Study of heavy endotoxins and neurotoxin from smooth and rough forms of "Shigella dysenteriae": separation and purification]. PMID- 4198796 TI - Weight loss following thermal injury. PMID- 4198797 TI - [Chemistry, pharmacology and administration of 1-methylthiocarbamoyl-2(1' methylallyl)thiocarbamoylhydrazine (METHALLIBURUM)]. PMID- 4198798 TI - [Immunological responses following TURISYNCHRON administration]. PMID- 4198800 TI - Beta-blocking agents in hay fever. PMID- 4198799 TI - Penicillins for Haemophilus infections. PMID- 4198801 TI - [Comparative study of the protein constituents of wool and hair]. PMID- 4198802 TI - [Demonstration of various esterases extracted from bacteria of the Proteus Providencia group]. PMID- 4198804 TI - [Hypothalamic dorso-ventral heterogeneity and autostimulation behavior in mice]. PMID- 4198803 TI - [Individual cells producing antibodies of different specificities. Increase in their frequency in mice treated with actinomycin D]. PMID- 4198805 TI - [Influence of breast feeding and weaning on the induction of adult-type circadian rhythm of plasma corticosterone in the rat]. PMID- 4198806 TI - [A technic of organotypic culture of mammalian islands of Langerhans]. PMID- 4198807 TI - [Cytostimulation by overload]. PMID- 4198808 TI - [Absence of lipopolysaccharide stimulation of B lymphocytes of the mouse peripheral lymph node]. PMID- 4198809 TI - [Mutagenic effects of acrolein and its two epoxides, glycidol and glycidal, on Saccharomyces cerevisiae]. PMID- 4198810 TI - [Demonstration of DNA and polysaccharides using a new "Schiff type" reagent]. PMID- 4198811 TI - [Plasma concentrations of 17 alpha-hydroxyprogesterone during the cow's cycle]. PMID- 4198812 TI - [Effects of somatotropin on the growth of the cartilage of the mandibular condyle and of the spheno-occipital synchondrosis in the young rat]. PMID- 4198813 TI - [Comparison of the effects of a bacterial endotoxin and formaldehyde on mouse macrophages]. PMID- 4198814 TI - Isolation of alpha-fetoprotein-producing cells from Yoshida ascites sarcoma and its clone. PMID- 4198815 TI - Presence of antigen related to the carcinoembryonic antigen in feces of normal adults. PMID- 4198816 TI - Tin-117m: production, chemistry and evaluation as a bone-scanning agent. PMID- 4198818 TI - Evolution of asymbiotic nitrogen fixation. PMID- 4198817 TI - Structure and biosynthesis of basement membranes. PMID- 4198819 TI - [Gastrointestinal protein loss in Waldenstrom's disease]. PMID- 4198820 TI - The 1974 reorganization of the British National Health Service--aims and issues. PMID- 4198821 TI - Sternoarticular septic arthritis in heroin users. PMID- 4198822 TI - Impaired carbohydrate metabolism during a mild viral illness. PMID- 4198823 TI - [Do hallucinogens cause chromosomal defects and abnormalities?]. PMID- 4198824 TI - Inhibition of respiration in the isolated eccrine sweat gland by ethacrynic acid. PMID- 4198826 TI - Photon interaction processes--their relative importance in bone and muscle. PMID- 4198825 TI - Regulation of protein synthesis in rat liver cell-free systems by amino acids. PMID- 4198827 TI - Cartilaginous esophageal ring: a cause of esophageal stenosis in infants and children. PMID- 4198828 TI - Dosimetry for total-body electron-beam therapy in the treatment of mycosis fungoides. PMID- 4198829 TI - Achievement of uniform dose without overlap in multi-port treatment fields, including inter-port shaped blocks. PMID- 4198830 TI - Puffing patterns in Drosophila melanogaster and related species. PMID- 4198831 TI - Chromomeres and genes. PMID- 4198832 TI - Replication in polytene chromosomes. PMID- 4198833 TI - The hydrogen clearance method in assessment of blood flow in cortex, white matter and deep nuclei of baboons. PMID- 4198834 TI - A venereological panorama. PMID- 4198835 TI - [The effect of glucose on the turnover of L-tryptophan in infants]. PMID- 4198836 TI - The Australia antigen in Brazilian blood donors. PMID- 4198837 TI - Biosynthesis of vitamin B12 by mesophilic and thermophilic strains of Bacillus megaterium. PMID- 4198838 TI - Development of tolerance to street heroin in addicted and nonaddicted primates. PMID- 4198839 TI - Parenteral feeding of surgical patients. PMID- 4198840 TI - [Application of multidimensional statistical methods to the prognosis of cardiac failure in acute myocardial infarct]. PMID- 4198841 TI - [Metabolic disorders during the acute stage of myocardial infarct]. PMID- 4198842 TI - [Pulmonary and coronary hemodynamics in the acute phase of myocardial infarct]. PMID- 4198843 TI - [Medical therapy of cardiac insufficiency in the initial stage of myocardial infarct]. PMID- 4198844 TI - [Assisted circulation by pulsated veno-arterial by-pass. Critical study of the results]. PMID- 4198845 TI - [Analgesic effects and hemodynamic and respiratory repercussions of the fentanyl droperidol combination in the acute stage of myocardial infarction]. PMID- 4198846 TI - [Determination of fibrinogen and fibrin degradation products (DFP) in the acute stage of myocardial infarction]. PMID- 4198847 TI - [Blood gases and arterial blood lactates in the acute stage of myocardial infarct]. PMID- 4198848 TI - [Measurement of coronary blood flow during myocardial infarct]. PMID- 4198849 TI - [Role of ischemia in left ventricular function disorders in the initial stage of myocardial infarct]. PMID- 4198850 TI - Neurofibroma of the larynx occurring with Von Recklinghausen disease. Report of a case. PMID- 4198851 TI - The chain length of the glycans in bacterial cell walls. AB - The glycan chain length of peptidoglycan was measured by reduction with NaB(3)H(4) and isolation of the resulting muramitol, indicative of the length of the chains as biosynthesized, and glucosaminol, which measured the length of the chains after rupture by endo-beta-N-acetylglucosaminidases. Measurement of the non-reducing terminal N-acetylglucosamine by Smith degradation confirmed the result. PMID- 4198852 TI - [Solitary schwannoma of the lumbosacral area. (Case report and literary review)]. PMID- 4198853 TI - [Role of the Breuer-Hering reflex in the regulation of respiration in the anesthetized rabbit and cat during progressive hyperoxic hypercapnia]. PMID- 4198854 TI - [Analgesic effects of periaqueductal gray matter stimulation on the mouth-opening reflex induced by stimulation of the dental pulp in the conscious, unrestrained cat]. PMID- 4198855 TI - [Spatial organization of the cat somate-motor cortex, established by intracortical stimulation in the animal under long-term preparation]. PMID- 4198856 TI - [D-glucosamine and D-galactosamine induced inhibition of anti-basal membrane antibody fixation on the glomerular basal membrane of the rabbit kidney]. PMID- 4198857 TI - [Solid-phase total synthesis of a tetradecapeptide having the chemical and biological properties of somatostatine]. PMID- 4198859 TI - [Study of bacteriophages of Rhizobium meliloti]. PMID- 4198858 TI - [Separation of 2 forms of endobronchial alpha 1-antitrypsin using affinity chromatography on "Sepharose-trypsin"]. PMID- 4198860 TI - [The immunochemical method of radial diffusion: its law and its practical consequences]. PMID- 4198861 TI - [Can somatotropin stimulate bone resorption?]. PMID- 4198862 TI - [Restorative activity of polyribonucleic acids and of polyvinylsulfate on irradiated bone marrow cell cultures]. PMID- 4198863 TI - [Calcium and the spasmogenic action of scorpion venom (Androctonus australis) on guinea pig ileum]. PMID- 4198864 TI - [Preferential release of newly-synthesized noradrenaline by ephedrine and hydroxyephedrine]. PMID- 4198865 TI - [Detection of anti-phage antibodies at the cellular level in a local hemolysis system]. PMID- 4198866 TI - Influence of dexamethasone on TRF induced TSH release in rats. PMID- 4198867 TI - A renewal attempt to compare the affinity of thyroxine-binding-globulin to thyroxine in normal and hyperthyroid sera. PMID- 4198868 TI - Spontaneous firing patterns of epileptic neurons in the monkey motor cortex. PMID- 4198869 TI - Behavioral impairment in the monkey following implantation of aluminum hydroxide on the temporal cortex: the role of cortical destruction. PMID- 4198870 TI - Responses of single neurons in the auditory cortex of squirrel monkeys to variants of a single call type. PMID- 4198871 TI - [Subunits of human chorionic gonadotropin]. PMID- 4198872 TI - [Clinical study of TRF test. 6. Hypothalamic hypothyroidism]. PMID- 4198873 TI - [Clinical study of TRF test. 7. TRF test response in hypothalamic pituitary disorders]. PMID- 4198874 TI - [Biochemical and immunological properties of human placental lactogen (hPL: human chorionic somatomammotropin, hCS). I. Extraction and purification of hPL (hCS)]. PMID- 4198875 TI - [Site of action of the coronary drug carbocromen]. PMID- 4198876 TI - [Quantitative immunochemical studies of ten individual proteins in the cerebrospinal fluid of children with acute inflammatory meningeal diseases]. PMID- 4198877 TI - Serological studies of Haemophilus influenzae. 3. The endotoxic effect of various antigen preparations and the relation between this effect and demonstrable precipitinogens. PMID- 4198878 TI - Studies in immunodermatology. 3. Induction of intraepithelial lesions in monkeys by intramucosal injections of pemphigus antibodies. PMID- 4198879 TI - Cromolyn in extrinsic and intrinsic asthma. PMID- 4198880 TI - Increased sensitivity to egg albumin in rats fed pristane. PMID- 4198881 TI - Enzymatic cleavage of (+)citramalate into pyruvate and acetyl-CoA in Bacillus sp. PMID- 4198882 TI - Interaction of chicken erythrocyte AMP deaminase with chelating agents. PMID- 4198883 TI - Spectroscopic properties of C-phycocyanin and of its alpha and beta subunits. PMID- 4198884 TI - Reactivity of oxytyrosinase toward substrates. PMID- 4198885 TI - Primary structure of human fibrinogen and fibrin. II. Structural studies on NH2 terminal part of gamma chain. PMID- 4198886 TI - Purification and properties of an extracellular polysaccharide containing amino sugars formed by Bacillus cereus. PMID- 4198887 TI - The application of cellulose carbonate to the preparation of water-insoluble immunoadsorbents used in the purification of antibodies to immunoglobulins. PMID- 4198888 TI - Further studies on the reaction of partial identity in quantitative immunoelectrophoretic patterns. PMID- 4198889 TI - Circularity of the Bacillus subtilis chromosome and further studies on its bidirectional replication. PMID- 4198890 TI - Biochemical properties of a cephalosporin beta-lactamase from Pseudomonas aeruginosa. PMID- 4198891 TI - Endotoxemia in febrile reactions during hemodialysis. PMID- 4198892 TI - Preparation and characterization of mouse intestinal phospholipase. PMID- 4198893 TI - Lowering of serum cholesterol by intestinal bacteria in cholesterol-fed piglets. PMID- 4198894 TI - Societal and individual determinants of medical care utilization in the United States. PMID- 4198895 TI - Separation of small circular DNA molecules from the blue-green alga Anacystis nidulans. PMID- 4198896 TI - X-ray diffraction of muscle labelled with antibody to troponin-C. PMID- 4198897 TI - [Risk of contamination of subjects in contact with patients with tuberculosis or pleurisy whether sputum positive or not]. PMID- 4198898 TI - [Recent diagnostic methods in dental pathology]. PMID- 4198900 TI - [Oral manifestations in erythema multiforme and differential diagnosis from other diseases]. PMID- 4198899 TI - [The effect of ionizing radiation on the salivary glands and saliva]. PMID- 4198901 TI - [Biological activity of synthetic thyrotropin releasing factor]. PMID- 4198902 TI - [Preventive prosthetics for a patient with neurofibromatosa localisata Recklinghausen]. PMID- 4198903 TI - Miniature eye movement. PMID- 4198904 TI - Slowed decay of the monkey's cone receptor potential by intense stimuli, and protection from this effect by light adaptation. PMID- 4198905 TI - [Holiday organization for children with chronic recurring attacks]. PMID- 4198906 TI - [Gonorrhea in women prior to pregnancy interruption]. PMID- 4198907 TI - Human leukemia, nucleic acids and viruses. Hypotheses and perspectives. PMID- 4198908 TI - Some characteristics of the proliferative activity of erythroblasts in untreated and treated acute leukaemia. PMID- 4198909 TI - Transplantable myeloid rat leukaemia induced by 7,12-dimethylbenz(a)anthracene. PMID- 4198910 TI - Acute myelomonocytic leukemia in a patient with Hodgkin's disease. PMID- 4198911 TI - Monoclonal origin of acute transformation of chronic myelogenous leukemia. Evidence from an acquired sex chromosome mosaic. PMID- 4198912 TI - [The effect of saturated and non-saturated fatty acids on the filtration pressure of platelet-rich plasma. Correlation with platelet aggregation]. PMID- 4198913 TI - Fetal factor VIII and IX levels in early pregnancy and their significance in prenatal diagnosis. PMID- 4198914 TI - Accumulation of drugs on melanin. PMID- 4198915 TI - Angiographic abnormalities in the urinary bladder wall after irradiation. I. Animal experiments. II. Clinical investigation. PMID- 4198916 TI - Turner syndrome with partial deletion of the X chromosome long arm. PMID- 4198917 TI - Visual sensitivity. PMID- 4198918 TI - Perception. PMID- 4198919 TI - Basic drives. PMID- 4198920 TI - [Anatomical and clinical aspects of the growing lower-arm bones, compared with distractio cubiti of the dog and Mandelung's deformity in man]. PMID- 4198921 TI - Role of inorganic nitrite in methaemoglobin formation after nitrate ester administration to the rat. AB - 1. Methaemoglobin is rapidly formed during the incubation of rat red cells with inorganic nitrite, whereas ethylene glycol dinitrate at a higher concentration has little effect.2. The concentrations of blood inorganic nitrite in the rat after ethylene glycol dinitrate or glyceryl trinitrate injection can be reproduced by the infusion of nitrite. The methaemoglobin formed after ethylene glycol dinitrate or glyceryl trinitrate injection is equivalent to that produced from nitrite infusions simulating its formation from the nitrate esters.3. It is concluded that methaemoglobin arising from nitrate ester administration is formed principally by the action of the metabolite inorganic nitrite. PMID- 4198922 TI - The effects of intravenous and intraduodenal feeding on nitrogen balance after surgery. PMID- 4198923 TI - The action of Bacillus subtilis liquefying amylase on 6-deoxy-6-iodoamylose. PMID- 4198924 TI - [Free vein transplants for long-term hemodialysis]. PMID- 4198925 TI - Iron metabolism of premature infants and their mothers. PMID- 4198926 TI - A genetic scheme for the blood systems ABO, Rh and MNSs, and an explanation of antigen-antibody patterns. PMID- 4198927 TI - The effect on reaction to painful stimuli of lesions in the centromedian nucleus in the thalamus of the monkey. PMID- 4198928 TI - The surgical production of chronic uremia in primates. PMID- 4198929 TI - Na+-dependent transport of threonine in Brevibacterium flavum. PMID- 4198930 TI - Alpha-D-fucosidase from Aspergillus oryzae: characterization of alpha-D fucosidase with alpha-D-galactosidase activity. PMID- 4198931 TI - A mathematical model for the determination of viscoelastic behavior of brain in vivo. II. Relaxation response. PMID- 4198932 TI - Studies of Ternidens deminutus Railliet & Henry, 1909 (Nematoda). I. External morphology. PMID- 4198933 TI - High voltage electron microscopy of cellular changes in the wet state. PMID- 4198934 TI - Resynchronization of RNA synthesis by coliphage Qbeta replicase at an internal site of the RNA template. PMID- 4198935 TI - A common conformational feature in several prokaryotic and eukaryotic 5 S RNAs: a highly exposed, single-stranded loop around position 40. PMID- 4198936 TI - The quantitative histochemistry of acid proteinase in the nervous system: localization in neurons. PMID- 4198937 TI - Experimental comparison of radioactive agents for studies of the placenta. PMID- 4198938 TI - Cost-benefit analysis of in vitro screening tests of thyroid function. PMID- 4198939 TI - Retreatment of recurrent nasopharyngeal malignancy using a radium mold. PMID- 4198940 TI - Prevention of infection of pacemaker pocket. PMID- 4198941 TI - [Antibacterial activity of lividomycin against several bacteria isolated from clinical specimens]. PMID- 4198942 TI - [Antimicrobial activity against E. coli and Pseudomonas of lividomycin]. PMID- 4198943 TI - [Fundamental and clinical evaluation of lividomycin]. PMID- 4198944 TI - [Therapeutic effects of lividomycin in urinary tract infections caused by Pseudomonas aeruginosa]. PMID- 4198946 TI - [Alpha-1-antitrypsin deficiency in a patient with mucoviscidosis]. PMID- 4198945 TI - Urinary antidiuretic hormone excretion during the menstrual cycle and pregnancy in the monkey. PMID- 4198947 TI - [Multiple tuberculous subcutaneous cold abscesses without visceral involvement]. PMID- 4198948 TI - [Anti-Rh immunoglobulin (D) subclasses and hemolytic disease of the newborn]. PMID- 4198949 TI - The nurse and the high-risk infant. PMID- 4198950 TI - Total intravenous nutrition by peripheral vein in neonatal surgical patients. PMID- 4198951 TI - Studies of the sudden infant death syndrome in King County, Washington. IV. Immunologic studies. PMID- 4198952 TI - Kinetic analysis of the base sequence heterogeneity of RNA molecules by RNA-DNA hybridization. PMID- 4198953 TI - Hybridization of nucleic acids to chromosomes. PMID- 4198954 TI - Role of the skin in amphibian sodium metabolism. PMID- 4198956 TI - Qualitative and quantitative comparison of C3 variant sera during the Bonn workshop. PMID- 4198955 TI - Some aspects of respiratory function in three siblings with Morquio-Brailsford disease. PMID- 4198957 TI - Haemolytic disease of the newborn caused by the rare Rhesus antibody anti-CX. PMID- 4198958 TI - Immunological dosage of Hb F and its correlation with the Singer test. Decrease of fetal hemoglobin with age. PMID- 4198959 TI - Report of a proficiency test for the hepatitis-B antigen. PMID- 4198960 TI - [Value of intermittent catheterization for the prevention of urinary tract infections in recent transverse lesions]. PMID- 4198961 TI - An improved automated method for the estimation of sialic acid released in the neuraminidase assay. PMID- 4198962 TI - Substrate specificity of a human-specific esterase. PMID- 4198963 TI - Immunodiffusion reaction with animal influenza viruses and antibody. PMID- 4198965 TI - [Extrapancreatic effects of sulfonylurea compounds. 3. Studies on the additional blood sugar decreasing and antilipolytic effect of tolbutamide, glibornuride, and glibenclamide on completely pancreatectomized dogs, chronically treated with insulin during acute experiment and following pretreatment with sulfonylurea compounds using small doses of sulfonylurea]. PMID- 4198964 TI - [Glibornuride, a new high-effective antidiabetic agent. Pharmacological and biochemical comparative studies in various animal species and animal experimental models]. PMID- 4198966 TI - [Extrapancreatic effects of sulfonylurea compounds. IV. Increase of the effect of insulin due to tolbutamide, glibornuride, and glibenclamide in vitro]. PMID- 4198967 TI - [Insulin liberation by blood sugar decreasing sulfonamides and by glucose in adult diabetic patients]. PMID- 4198968 TI - [Studies on dose-response relationship of various sulfonylurea derivatives of the old and the new generation with further hints to extrapancreatic mechanisms of decreasing blood sugar]. PMID- 4198969 TI - The disorder of hyaluronic acid metabolism in cultured skin fibroblasts derived from a patient with the Hurler syndrome. AB - The metabolism of hyaluronic acid in cultured skin fibroblasts derived from a patient with the Hurler syndrome and from a normal subject was examined. 1. An increased net incorporation of [(3)H]glucose into the hyaluronic acid fraction of the Hurler-syndrome cells occurred when compared with normal cells. 2. During a ;chase' period, approx. 35% of the radioactivity derived from glucose was lost from the hyaluronic acid fraction of the Hurler-syndrome cells, whereas the normal cells retained all their radioactivity. 3. Although the Hurler-syndrome cells contained a ninefold greater amount of hyaluronic acid than normal cells, simultaneous determination of the specific radioactivity derived from the label revealed a value for the Hurler-syndrome cells one-half that of normal cells. These results are taken to indicate that the Hurler cells synthesize hyaluronic acid de novo at a higher rate than do normal cells. 4. Exposure of Hurler syndrome cultured fibroblasts to a crude urine corrective-factor preparation (Neufeld & Cantz, 1971), now known to contain alpha-l-iduronidase, the specific Hurler-syndrome corrective factor (Bach et al., 1972), decreased the hyaluronic acid content to near-normal values before any effect was observed on [(3)H]glucose incorporation into the hyaluronic acid fraction. 5. In addition, the hyaluronic acid content of the normal cells decreased after exposure to the corrective factor of urine. 6. The mobilization of hyaluronic acid in Hurler syndrome and normal cells exposed to the crude corrective-factor preparation of urine caused a decrease in specific radioactivity in the ;corrected' Hurler syndrome cells and an increase in specific radioactivity in the ;corrected' normal cells. PMID- 4198970 TI - Isolation and characterization of membrane-bound polysomes from ascites tumor cells. PMID- 4198971 TI - [Effect of illumination on RNA synthesis and poly(adenylic acid) sequences in cultures of etiolated Euglena gracilis]. PMID- 4198972 TI - ATP regeneration using immobilized carbamyl phosphokinase. PMID- 4198973 TI - Immunochemical characterization of commercial protease products. PMID- 4198974 TI - Differences in the urea-extracted proteins of mouse epidermis and squamous cell carcinomata determined by fluorescence microscopy. AB - Fluorescence microscopy was used to demonstrate differences in the urea extractable antigens of mouse epidermis and squamous cell carcinoma. When serum- and normal tissue sediment-absorbed antisera prepared against mouse epidermal urea-extracted proteins were further absorbed with carcinoma urea antigens, antisera specific for epidermis resulted. When antisera raised against the urea extractable proteins of mouse squamous cell carcinomata were serum- and normal tissue sediment-absorbed and then further absorbed with epidermal urea antigens, antisera were prepared which stained papilloma and carcinoma, but not epidermis, and thus these antisera were not specific for carcinoma. Antisera prepared against the urea-extractable proteins of human epidermis reacted in immunodiffusion in agar with the epidermal urea proteins, but not with human squamous cell carcinoma urea proteins. Also antisera prepared against the carcinoma urea-extractable proteins reacted with these proteins in agar, but no reaction occurred with the epidermal urea-extractable proteins. PMID- 4198975 TI - Mechanisms of selective uptake of 2-methyl-4-naphthoquinol bis disodium phosphate, into some mammalian cells in tissue culture. AB - Earlier papers have described the selective uptake of the radioactive drug 2 methyl 6,7-ditritio-1, 4-naphthoquinol bis disodium phosphate into some human tumour cells in tissue culture. This work examines these results in greater detail. The kinetics of the uptake process into HEp/2 cells and its precise dependence on the experimental conditions are described. It is shown that an alkaline phosphatase (APase) is present on the surface of HEp/2 cells and that this is responsible for the uptake of label. L cells do not take up the radioactive label and are shown not to possess significant quantities of APase. PMID- 4198976 TI - [Variations in the circadian rhythm of urinary 17-hydroxycorticosteroids in young children as a function of their behavioral profile]. PMID- 4198978 TI - [The multiplication of sigma virus in several primary cultures and in a continuous line of drosophila cells from embryos which perpetuate a defective sigma virus]. PMID- 4198977 TI - [Interaction of yeast hexokinase with its substrates]. PMID- 4198979 TI - [Effects of thyroidectomy on phospholipase A2, lipase, cholesterolesterase, and trypsin activity of rat pancreatic juice and pancreas]. PMID- 4198980 TI - [Specific cytological characteristics of the pars tuberalis of the pituitary gland and its early differentiation in the rat fetus]. PMID- 4198981 TI - Metabolic effects of PCB (polychlorinated biphenyls) on the brown trout (Salmo trutta). PMID- 4198982 TI - Free radical mechanism for phenylhydrazine action on the retractor unguis muscle of the grasshopper, Romalea microptera. PMID- 4198983 TI - Vorticella--a model for chemopharmacodynamic action on smooth muscle. PMID- 4198984 TI - The relationship between total body potassium and exchangeable body potassium measured at 24 hours and 44 hours after administration of 43K. PMID- 4198985 TI - Sympathetic innervation of the ciliary muscle in monkeys. PMID- 4198986 TI - The effect of lipids from Listeria monocytogenes on immune response in mice. PMID- 4198987 TI - Pattern of recruitment of oocytes to second growth phase in normal toads, and in hypophysectomized toads, Bufo bufo bufo (L.), treated with gonadotropin (HCG). PMID- 4198989 TI - The immunoglobulins derived from a VH-CH recombinant rabbit and its normal relatives. I. Measurements of heavy chain molecular weights and allotypes of colostral IgA. PMID- 4198988 TI - [Effect of local antihidrotic agents]. PMID- 4198990 TI - Cortical bone remodeling and bone mass in primary osteoarthrosis of the hip. PMID- 4198991 TI - Plasmocid encephalopathy in the rhesus monkey: a study of selective vulnerability. PMID- 4198993 TI - The dangers of oral feeding in the presence of cuffed tracheostomy tubes. PMID- 4198992 TI - Prostaglandin E2 and gastric acid secretion in man. AB - 1. Extracts of human stomach homogenized in Krebs solution had more PGE(2)-like activity than tissue homogenized in acid/ethanol or in the presence of indomethacin, indicating that the tissue can synthesize PGE(2).2. The distribution and synthesis of PGE(2)-like substance in human stomach was determined by extracting frozen sections cut parallel to the mucosal surface. Peak levels usually occurred at a depth of 0-600 mum in the mucosa.3. Small amounts of a PGE(2)-like substance were present in basal gastric juice, and its concentration was usually even lower in secretion stimulated by pentagastrin or histamine.4. Submaximal acid secretion produced by I.V. infusion of pentagastrin generally fell slightly when indomethacin was administered rectally to inhibit PG synthesis.5. These experiments, together with the findings that orally administered PGE compounds do not inhibit human gastric acid secretion, seem to argue against a possible inhibitory role for PGE(2) in gastric acid secretion in man.6. If this is so, it would follow that gastric bleeding caused by aspirin like drugs is not due to increased acid secretion. A hypothesis is presented that tissue damage following vasoconstriction and ischaemia, due to inhibition of PG synthesis in blood vessels, contributes to the bleeding. PMID- 4198994 TI - [Demonstration of subliminal erythrocytic immune antibodies by cryoconcentration of the sera]. PMID- 4198995 TI - Ultrastructure and functional states of mitochondria. Effect of fixatives on the stabilization of unstable configuration. PMID- 4198996 TI - Reversibly temperature sensitive phototransduction mutant of Drosophila melanogaster. PMID- 4198998 TI - Neurofibromatosis (Von Recklinghausen's disease) and juxta-medullary spinal lipoma. PMID- 4198997 TI - [Detection of sulfonamides in milk]. PMID- 4198999 TI - Contributions to the optimal use of human blood. II. The large-scale preparation of prothrombin complex. A comparison between two methods using the anion exchangers DEAE-cellulose DE 52 and DEAE-sephadex A-50. PMID- 4199000 TI - The presence of I, H, HI, and i blood group substances in the tissues of rabbits, monkeys, and guinea pigs. PMID- 4199001 TI - Glycogen synthesis in rat diaphragm in vivo: a biphasic effect of insulin on glycogen synthetase enzyme. PMID- 4199002 TI - Adenohypophysial growth and thyroxine binding: effects of steroid hormones. PMID- 4199003 TI - The epidemiology of hepatitis B infections in Africa: results of a pilot survey in the Republic of Senegal. PMID- 4199004 TI - Agenesis of the corpus callosum in the median facial cleft syndrome and associated ocular malformations. PMID- 4199005 TI - Ocular abnormalities of a child associated with familial microcephaly. PMID- 4199006 TI - Formaldehyde-glutaraldehyde fixation. PMID- 4199007 TI - Tissue response to the movement of bones. PMID- 4199008 TI - Faciolingual tooth movement: its influence on the root and cortical plate. PMID- 4199009 TI - [Adenine nucleotides of Drosophila. Biosynthesis of ATP and ADP in larvae deprived of food and in refed larvae]. PMID- 4199010 TI - [Serological, chemical and immunochemical studies on Erysipelothrix insidiosa. 13. Immunizing antigen]. PMID- 4199011 TI - Chemostat studies on the regulation of glucose metabolism in Pseudomonas aeruginosa by citrate. AB - The effect of the relative concentrations of citrate and glucose on the regulation of key enzymes of the direct oxidative, phosphorylative, Entner Doudoroff and pentose-cycle pathways of glucose metabolism in Pseudomonas aeruginosa has been investigated in continuous culture under conditions of NH(4) (+)-limitation. For comparison isocitrate dehydrogenase and aconitase were also assayed. Measurements were made for steady-state and transient conditions and the effect of growth rate was also studied. When cells grew on 75mm-citrate the glucose concentration had to attain 6-8mm before significant induction of enzymes of glucose metabolism occurred; the specific activities increased further as the result of both raising the glucose concentration to 30mm and then subsequently lowering the citrate to 60mm and then to 45mm. The specific activities of the glucose enzymes increased immediately during the transient period between the steady states characteristic of growth on 6mm- and 8mm-glucose, the increase continuing for about two doubling times. The converse experiment of adding increasing citrate concentrations to 45mm-glucose medium revealed an immediate induction of the citrate-transport system, oxidation of citrate following the increase in citrate concentration up to 8mm. Between 8mm- and 16mm-citrate a marked repression of gluconate, glucose 6-phosphate and 6-phosphogluconate dehydrogenases and the Entner-Doudoroff enzymes occurred. Increased growth rate in citrate medium resulted in decreased specific activities of glucose 6 phosphate dehydrogenase and isocitrate dehydrogenase. Increased growth rate in citrate-glucose medium gave decreased specific activities of isocitrate dehydrogenase and aconitase whereas the activities of some of the glucose enzymes decreased initially but then increased at the highest growth rate (0.5h(-1)), at which a marked increase in glucose utilization occurred. These observations accord with the regulation of glucose enzymes by induction with glucose or its metabolites and repression by citrate or its metabolic products. PMID- 4199012 TI - The regulation of transport of glucose and methyl alpha-glucoside in Pseudomonas aeruginosa. AB - The methyl alpha-glucoside-transport system of Pseudomonas aeruginosa has been characterized with respect to its specificity, energy-dependence, kinetics and regulation. The uptake of glucose involved two components, one of which transported glucose (K(m)=8mum) and methyl alpha-glucoside (K(m)=2.8mm) whereas the other was more complex, involving the extracellular activity of glucose dehydrogenase. Mutants defective in this enzyme have been isolated and characterized. The methyl alpha-glucoside-glucose-transport system was repressed when the organism was grown in the absence of glucose; the induction of this transport system by glucose, and its activity once induced, were inhibited by products of citrate metabolism. PMID- 4199013 TI - The uptake of 2-deoxy-D-glucose by Pseudomonas aeruginosa and its regulation. AB - The non-metabolizable glucose analogue 2-deoxy-d-glucose is taken up by Pseudomonas aeruginosa against a concentration gradient, in a predominantly unchanged form. d-Glucose competitively inhibits 2-deoxy-d-glucose uptake and also causes a rapid exit of intracellular 2-deoxy-d-glucose. Thus these two sugars share the same stereospecific carrier system, and glucose transport can be studied reliably with 2-deoxy-d-glucose. The transport system is inducible, and is strongly repressed by a number of organic acids such as acetate, citrate, succinate, fumarate and malate, even in the presence of adequate excess of the inducer (d-glucose). Repression by organic acids can be relieved by transferring cells to a glucose medium, but in the presence of chloramphenicol the cells fail to recover from repression, indicating that the formation of the transport system involves the synthesis of protein. The results demonstrate that the regulation of glucose metabolism effected by citric acid-cycle intermediates in P. aeruginosa is manifest at the level of the glucose-transport system. PMID- 4199015 TI - [Action of PHA-R and concanavalin A on embryonic cells during embryogenesis]. PMID- 4199014 TI - Interrelationship of islet metabolism, adenosine triphosphate content and insulin release. AB - The oxidation of some exogenous substrates and their effects on ATP content and insulin release in mouse pancreatic islets were measured. The ATP concentration of islets incubated without exogenous substrate shows a gradual decrease, which can be prevented by glucose or mannose (20mm) or leucine (2.5mm); d glyceraldehyde (5mm) is as effective as glucose (5mm); fructose or N acetylglucosamine (20mm), pyruvate (10mm) and dl-3-hydroxybutyrate (2mm) are less effective; galactose (20mm), acetate (10mm), octanoate (2mm) and succinate (10mm) have no ATP-maintaining ability. Islets oxidize glucose, mannose, glyceraldehyde, leucine and, less readily, N-acetylglucosamine and glucosamine; galactose, however, is poorly metabolized. Mannoheptulose inhibits the oxidation of glucose but not of glyceraldehyde. Insulin release, measured over a 2h incubation, is stimulated by glucose, mannose, leucine, glyceraldehyde or glucosamine but not by fructose or N-acetylglucosamine. The latter, however, potentiates the effects of glucose or glyceraldehyde (5mm) or leucine (2.5mm) on release; the potentiating effects are inhibited by mannoheptulose, which also blocks glucose-, but not glyceraldehyde- or leucine-stimulated release. In the presence of glucose (20mm), metabolic inhibitors depress insulin release and islet ATP content in parallel. However, rates of insulin release and ATP content measured after incubation with various combinations of exogenous substrates do not appear to be correlated. Sulphonylureas stimulate insulin release but decrease islet ATP concentrations. These results provide further evidence of a close association between the metabolic activity of exogenous substrates and their ability to initiate insulin release. Glucoreceptor models are formulated in the light of these observations and discussed. PMID- 4199016 TI - [Characteristics and topography of immunoreactive hypothalamic neurons with antibodies against synthetic LRF]. PMID- 4199017 TI - [Action of testosterone on the genital ducts of reptile embryos]. PMID- 4199018 TI - [Effect of cytochalasine B on morphogenic interdigital necrosis in the chick embryo foot]. PMID- 4199019 TI - [Sensory capacity and level of sexual activity in Prealpes and Ile-de-France rams]. PMID- 4199020 TI - [Presence in the genus Bacillus of systems which hydrolyse the beta(1-4) bonds of agarose]. PMID- 4199022 TI - [Tissular distribution of the alloantigens of the secretory groups (digestive groups) in the dog]. PMID- 4199021 TI - [Immunological properties of bacterial cell walls. Comparative study of Corynebacterium parvum and of Bacillus megaterium]. PMID- 4199023 TI - [Mechanisms of immunological facilitation studied in vitro. Site of action of antibodies which protect against a specific lymphocytotoxic agression]. PMID- 4199024 TI - Toxicologic and pharmacologic aspects of rifampin. PMID- 4199025 TI - [Double-blind and open study of a delayed-action trinitroglycerine preparation]. PMID- 4199026 TI - Effect of protein-calorie malnutrition on the development of social behavior in rats. PMID- 4199027 TI - Influence of insulin and glybenclamid on the intestinal disaccharidases of subtotally pancreatectomized rats. PMID- 4199028 TI - [Bacteriological criteria of rifampicin and ethambutol resistance]. PMID- 4199029 TI - [Sensitivity to rifampicin and ethambutol of mycobacteria resistant to isoniazid or streptomycin]. PMID- 4199031 TI - Mandibular bone grafting in trauma. PMID- 4199030 TI - [Experimental in-vitro and in-vivo studies of the antibacterial effect of rifampicin and ethambutol]. PMID- 4199032 TI - Injuries of the face and jaws in children. PMID- 4199033 TI - A technique of vestibular plasty using a free mucosal graft from the cheek. PMID- 4199034 TI - Reversibility of surgically induced dental ankylosis in rats. PMID- 4199035 TI - Serum IgD concentrations in children with atopic diseases. PMID- 4199036 TI - Neutral sucrose sedimentation of very large DNA from Bacillus subtilis. I. Effect of random double-strand breaks and centrifuge speed on sedimentation. PMID- 4199037 TI - Neutral sucrose gradient sedimentation of very large DNA from Bacillus subtilis. II. Double-strand breaks formed by gamma ray irradiation of the cells. PMID- 4199038 TI - Relation between single-strand DNA mass and sedimentation distance in alkaline sucrose gradients. PMID- 4199039 TI - [Secretory function of the middle ear mucous membrane--from the standpoint of immunochemistry]. PMID- 4199041 TI - Intravenously induced infantile intoxication with ethanol. PMID- 4199040 TI - Hypothalamic gigantism. PMID- 4199042 TI - Pigmented lesions of incontinentia pigmenti in a neonate. PMID- 4199043 TI - Synthesis of (plus-)-trans-11-methylthio-1,2,3,4,6,7,12,12b octahydrohydroxyindolo(2,3-a)quinolizine. PMID- 4199044 TI - Antigenicity of vascular heterografts. PMID- 4199045 TI - [Determination of thyroxine--its problems and clinical application]. PMID- 4199046 TI - Studies on the primitive lymphatic apparatus in the blood vascular system of the lungs of Macaca cyclopis. PMID- 4199047 TI - The M. temporalis of the Formosan monkey. PMID- 4199048 TI - The failing blade-vent implant. PMID- 4199049 TI - Isolation of the teichoic acid of Bacillus subtilis 168 by affinity chromatography. PMID- 4199051 TI - [Radiotherapy schedules for classified bladder cancer]. PMID- 4199050 TI - Isolation and partial characterization of arachin-P6. PMID- 4199052 TI - [Spontaneous epilepsy of monkeys in captivity]. PMID- 4199053 TI - Effects of immunizing turkeys with ovine luteinizing hormone. PMID- 4199055 TI - Lean diets and atherosclerosis. PMID- 4199056 TI - Treatment and prevention of childhood lead poisoning: new approach. PMID- 4199054 TI - Toxicity of systemic insecticides. Toxicological considerations in using of ganophosphorus insecticides. PMID- 4199057 TI - Bioavailability studies of nitrates in the dog. PMID- 4199058 TI - The metabolism of 5,5-diphenylhydantoin (DPH) in nonpregnant and pregnant Rhesus monkeys. PMID- 4199059 TI - [Basidiomycetes and ascomycetes with "iterative" dangeardies]. PMID- 4199060 TI - [New phylogenic data on Tylenchoidea (Nematoda)]. PMID- 4199061 TI - [The role of cytoplasmic microfilaments in the displacement and transformation of Leydig cells in histiotypic culture]. PMID- 4199062 TI - [Behavior of nucleoligenic chromosomes in Asellus (Proasellus) meridianus Racovitza and Asellus aquaticus Linne]. PMID- 4199063 TI - [Morphogenetic effect of chorionic and serum gonadotropins (HCG and PMSG) on the Leydig cells of the pig testicle in organotypic culture]. PMID- 4199064 TI - [Suppression by LSD of the inhibiting effect of the dorsal nucleus of the raphe on the interneurons of layer V of the dorsal horn of the spinal cord in the cat]. PMID- 4199065 TI - [Histochemical study of the human placenta. Ultrastructural localization of the chorionic somatomammotrophic hormone using an immunocytochemical technic with peroxidase]. PMID- 4199066 TI - [Formation of complex 3H-estradiol-macromolecules in cytosolic and nuclear fractions of fetal guinea-pig renal tissue]. PMID- 4199067 TI - [Hydrolysis of glucosiduronates of urinary steroids related to pregnane and estrane by a new fast-acting E. coli beta-glucuronidase]. PMID- 4199068 TI - [Methods of cicatrization of the flank of 5-day-old chick embryos]. PMID- 4199069 TI - [Measurement and properties of benzo(a)pyrene-hydroxylase]. PMID- 4199070 TI - [Influence of high levels of blood tryptophan on the penetration of this amino acid into the mouse brain]. PMID- 4199071 TI - [Attempted demonstration of sequences common to kinetoplastic and nuclear DNA in Trypanosoma]. PMID- 4199072 TI - [Attempted identification of the plasmacyte]. PMID- 4199073 TI - [Microfluorometric verification of lowered monoamine levels in the external region of the medial eminence in the bi-adrenalectomized rat]. PMID- 4199074 TI - [Extraction and concentration of human plasma calcitonin using coupled antibodies on a solid support]. PMID- 4199075 TI - [Effect of the dietary energy level on the utilization of acetate as a precursor of milk fatty acids by goat mammary gland]. PMID- 4199076 TI - [Preliminary study of the circadian rhythm of 17-hydroxycorticosteroids in young children in a child-care center]. PMID- 4199077 TI - [Demonstration of an odor linked to lactation and stimulating aggressive behavior in a group of female mice]. PMID- 4199078 TI - [In vitro study of the mechanisms of intercellular adhesion in the chick embryo: effect of blood]. PMID- 4199079 TI - [The behavior of sections of mouse embryo neural tube and cord transplanted in the place of the homologous organs in the chick embryo]. PMID- 4199080 TI - [Influence of variations in atmospheric ozone on some biological activities of ultraviolet solar radiation]. PMID- 4199081 TI - [Mathematical model of the growth of Candida lipolytica on n-paraffins]. PMID- 4199082 TI - [Adjuvant activity of Gram-negative bacterial peptidoglycans in delayed hypersensitivity]. PMID- 4199083 TI - Studies on acute phase proteins of rat serum. 3. Site of synthesis of albumin and alpha 1-acid glycoprotein and the contents of these proteins in liver microsome fractions from rats suffering from induced inflammation. PMID- 4199084 TI - The amino acid sequence of Streptomyces griseus trypsin. I. The peptic peptides. PMID- 4199085 TI - Variations in genetic architecture at different doses of gamma-radiation as measured by longevity in Drosophila melanogaster. PMID- 4199086 TI - The principal liver carcinogen-protein conjugate after a single dose of hepatic azocarcinogen. PMID- 4199087 TI - Immunochemical studies on lactate dehydrogenase: preparation and characterization of anti-M lactate dehydrogenase antiserum: development of an immunochemical assay for lactate dehydrogenase isoenzymes in human serum. PMID- 4199088 TI - Quantitation of human IgG by rocket immunoelectrophoresis at pH 5 by use of carbamylated antibodies. A routine laboratory method. PMID- 4199089 TI - Serum immunoglobulins, complement component levels and autoantibodies in liver disease. PMID- 4199091 TI - Immunoglobulin alterations associated with heroin addiction. PMID- 4199090 TI - Immunological studies in children undergoing tonsillectomy. PMID- 4199093 TI - Some factors affecting precipitation and complex formation of an IgG cryoglobulin. PMID- 4199094 TI - Anti-chromium barrier creams. PMID- 4199092 TI - In vitro synthesis of immunoglobulins, secretory component and complement in normal and pathological skin and the adjacent mucous membranes. PMID- 4199095 TI - Factors affecting care of the patient: clients, government policy, role of the family and social attitudes. PMID- 4199096 TI - Effect of aging on the marmoset periodontium. PMID- 4199097 TI - Verrucous carcinoma of the mouth. PMID- 4199098 TI - Familial gingival fibromatosis: an unusual pathology. PMID- 4199099 TI - Mitostatic action of vinblastine sulphate on oral epithelia of hamsters. PMID- 4199100 TI - Changes in cell cycle characteristics in hamster cheek pouch epithelium during treatment with DMBA. PMID- 4199101 TI - Fibrous dysplasia: a nosologic problem in the diagnosis of fibro-osseous lesions of the jaws. PMID- 4199102 TI - Scanning electron microscopy of calcium hydroxide induced bridges. PMID- 4199103 TI - [Radiotherapy of malignant pleural mesotheliomas. Apropos of 14 cases irradiated at high doses]. PMID- 4199104 TI - [Type II mucolipidosis. I-cell disease]. PMID- 4199105 TI - Isolation and properties of Bacillus subtilis strains lysogenized by a clear plaque mutant of bacteriophage phi 105. AB - A clear plaque mutant of the temperate Bacillus phage phi105 lysogenized a small fraction of infected cells forming an integrated prophage at or near the normal phi105 insertion site. These lysogens exhibited a spontaneous induction rate approximately 1,000-fold lower than wild type and were noninducible (ind(-)) by mitomycin C. Prophage was induced, however, when competent cultures were incubated with transforming DNA. The ind(-) phenotype could not be attributed solely to the clear plaque mutation and appears to involve a cell-specific factor. Lysogenization by the clear plaque mutant, in contrast to wild-type phage, did not cause a marked reduction in transformation efficiency. PMID- 4199106 TI - DNA-mediated prophage induction in Bacillus subtilis lysogenic for phi 105c4. AB - Prophage was induced when strains of Bacillus subtilis 168 lysogenic for phi105c4 were grown to competence and exposed to specific bacterial DNAs. The time course of phage production was similar to that observed for mitomycin C induction of wild-type prophage. Induction was directly dependent upon DNA concentration up to levels which were saturating for the transformation of bacterial auxotrophic markers. The extent of induction varied with the source of DNA. The burst of phage induced by DNA isolated from a W23 strain of B. subtilis was fivefold less than that induced by DNA from B. subtilis 168 strains, while B. licheniformis DNA was completely inactive. This order of inducing activity was correlated with the ability of the respective DNAs to transform auxotrophic markers carried by one of the phi105c4 lysogens. Differences in inducing activity also were observed for different forms of phi105 DNA. The DNAs isolated from phi105 phage particles and phi105c4 lysogens were inactive, whereas DNA from cells lysogenized by wild-type phi105 induced a burst of phage. When tested for transforming activity, however, both phi105c4 and phi105 lysogen DNAs were equally effective. An induction mechanism which involves recombination at the prophage insertion site is proposed to explain these differences. PMID- 4199107 TI - Effects of actinomycin D and ultraviolet and ionizing radiation on Pichinde virus. AB - Actinomycin D (0.05 mug/ml) suppresses the synthesis of ribosomal RNA of baby hamster kidney (BHK21) cells. The production of infectious Pichinde virus was enhanced in the presence of actinomycin D, although the production of virus particles was not substantially different from cultures inoculated in the absence of the drug. By prelabeling BHK21 cells with (3)H-uridine and then allowing the virus to replicate in the presence of actinomycin D, it was possible to show that ribosomal RNA synthesized prior to infection was incorporated into the virion. A single-hit kinetics of inactivation of Pichinde virus was observed with ultraviolet light, suggesting that the virus contains only a single copy of genome per virion. Comparison of the inactivation kinetics by gamma irradiation of Pichinde virus with Sindbis and rubella virus indicated that the radiosensitive genome of Pichinde virus was about 6 x 10(6) to 8 x 10(6) daltons. This value is greater than the 3.2 x 10(6) daltons which was estimated by biochemical analysis. One possible explanation considered is that the ribosomal RNA of host cell origin is functional and accounts for the differences in genome size estimated by the two methods. PMID- 4199108 TI - Synthesis of bacteriophage phi 29 proteins in Bacillus subtilis. AB - Seventeen bacteriophage phi29 proteins were detected in ultraviolet light irradiated Bacillus subtilis by autoradiography of polyacrylamide slab gels. The appearance of phi29 proteins occurred either before or concomitantly with viral DNA replication. Viral proteins detected early in the infectious cycle consisted of nine polypeptides ranging from 5,200 daltons to 54,000 daltons. Two of the early proteins were identified as, respectively, the major capsid protein and the protein comprising the filaments which extend from the head of the virus. Late phi29 proteins were composed of eight polypeptides ranging from 14,000 daltons to 95,000 daltons. Only three late proteins were noncapsid proteins. Among the early proteins, six were synthesized at diminishing rates late in the infectious cycle. One of the early proteins (protein 12) lacked histidine, whereas two (proteins 10 and 15) lacked tryptophan. Among the 17 proteins detected, 10 were viral noncapsid proteins. The amount of viral genetic information required to code for the 17 proteins detected in these experiments (81% of the potential genetic information of phi29 DNA) compares favorably with the genetic information detected as mRNA in a previous report, 85% of the potential information on the phi29 chromosome. PMID- 4199110 TI - A survey of mycobacterial isolates from the Randwick Chest Hospital, Sydney, in an 18-month period, 1970 to 1971. PMID- 4199109 TI - Heat induction of prophage phi 105 in Bacillus subtilis: bacteriophage-induced bidirectional replication of the bacterial chromosome. AB - A mutant of Bacillus subtilis, dna-1, which cannot initiate new rounds of DNA replication (obtained from N. Sueoka) was lysogenized with wild-type phi 105 and with the heat-inducible mutant phi 105 cts23. Bacteria were incubated at the permissive temperature in the presence of chloramphenicol and then shifted to the nonpermissive temperature where induction of phi 105 cts23 occurs. DNA made after the shift was labeled with a density label, and the distribution of bacterial and phage markers in replicated and unreplicated DNA was determined. Similar experiments were performed with nonlysogenic dna-1 infected with phage phi 105 cts23 after the temperature shift. The results show that after induction of phi 105 cts23 prophage, bacterial markers on either side of the prophage replicate at an increased rate compared to more distant markers. No selective stimulation of bacterial DNA synthesis was observed on infection or after shifting bacteria lysogenic for noninducible phage to the higher temperature. Attempts to suppress the initiation mutation dna-1 by phage phi 105 were unsuccessful. PMID- 4199111 TI - Sodium cromoglycate in the treatment of chronic allergic rhinitis. PMID- 4199112 TI - The management of the sick diabetic--the physician's role in the prevention of diabetic coma. PMID- 4199113 TI - [Hemodialysis in the child]. PMID- 4199114 TI - [Radiotherapy in lymphogranulomatosis]. PMID- 4199115 TI - Clinical utilization of plasmapheresis and cyclophosphamide in the treatment of malignant lymphoproliferative processes. PMID- 4199116 TI - The influence of various dietary ascorbic acid levels on serum ascorbic acid and serum cholesterol values of the baboon (Papio ursinus) during captivity. PMID- 4199117 TI - Effect of ethylenebis (dithiocarbamic acid)disodium salt(nabam)and ethylenebis(dithiocarbamato)manganese(maneb) on Xenopus laevis development. PMID- 4199118 TI - Appendicular skeletal and visceral malformations induced by thalidomide in bonnet monkeys. PMID- 4199119 TI - Teratogenic effects of 5-bromodexyuridine on the external morphology of Drosophila melanogaster. PMID- 4199120 TI - Immunological studies on Egyptian cobra antivenin. PMID- 4199121 TI - Immunological studies on Naja nigricollis antivenin. PMID- 4199122 TI - Iodination of cobrotoxin. PMID- 4199123 TI - Changes in antigenic character of fresh Australian snake venom upon aging. PMID- 4199124 TI - Purification of Aphanizomenon flos-aquae toxin and its chemical and physiological properties. PMID- 4199125 TI - Immunological studies of scorpion (Buthus minax, L. Koch) venom. PMID- 4199126 TI - Von Willebrand's syndrome presenting as an acquired bleeding disorder in association with a monoclonal gammopathy. PMID- 4199128 TI - Menstrual cycle characteristics and side of ovulation in the Rhesus monkey. PMID- 4199127 TI - Chronic hemolytic anemia due to cold agglutinins: a 20-year history of benign gammopathy with response to chlorambucil. PMID- 4199129 TI - A comparative study of the mechanisms of passive cutaneous anaphylaxis induced by mouse IgG, rabbit IgG, and rabbit F (ab')2 antibodies. I. The role of serotonin and histamine. PMID- 4199130 TI - The cardiac auto-immune system. IX. Auto-immune myocarditis in rabbits immunized with rabbit heart. PMID- 4199131 TI - The canine respiratory immune response. PMID- 4199132 TI - Suppression of anaphylactic responses in mice by antilymphocyte sera, normal sera, and egg albumin. PMID- 4199133 TI - Reduction by serum proteinase inhibitors of B. subtilis proteinase-induced hypersensitivity reactions. PMID- 4199134 TI - Human leukocyte migration inhibition as an indicator of cellular hypersensitivity to soluble antigens. PMID- 4199135 TI - Effects of phagocytosis by rabbit granulocytes on macromolecular synthesis and degradation in different species of bacteria. AB - Phagocytosis and killing of gram-positive Bacillus megaterium and Micrococcus lysodeikticus by granulocytes in vitro is associated with almost immediate cessation of bacterial protein synthesis. By contrast, protein synthesis by Escherichia coli continues after ingestion and killing. After preincubation of E. coli with intact granulocytes for 15 min, when 95% or more of the bacteria can no longer multiply, induction of beta-galactosidase proceeds at rates about half of control values. With disrupted granulocytes, which kill E. coli as rapidly as intact cells, the rate of induction of beta-galactosidase does not fall until after 30 min of preincubation. We attribute the different effects of phagocytosis on the biochemical apparatus of these microorganisms to the different fates of their envelopes. Specifically labeled protein, ribonucleic acid, deoxyribonucleic acid, and lipid of all three species of bacteria and peptidoglycan of E. coli are apparently incompletely degraded during phagocytosis. However, the cell walls of M. lysodeikticus and B. megaterium undergo rapid and almost complete degradation. The resulting structural disintegration of these gram-positive microorganisms must cause extensive biochemical disorganization as well. Our evidence indicates that the E. coli envelope, on the other hand, retains sufficient structural organization to preserve integrated biochemical function for at least 1 h after the bacteria have lost the ability to multiply. PMID- 4199136 TI - Guanosine diphosphate-L-fucose glycopeptide fucosyltransferase activity in Corynebacterium insidiosum. AB - The biosynthesis of a phytotoxic glycopeptide of Corynebacterium insidiosum involves guanosine diphosphate-l-fucosyltransferase activity. This enzyme activity is most consistently associated with the cellular membranes fraction. The optimal pH for the transfer reaction is 7.5. The partially hydrolyzed toxin serves as an acceptor (primer) of l-fucose. PMID- 4199137 TI - Specificity of the tyrosine-phenylalanine transport system in Bacillus subtilis. AB - l-Tyrosine and l-phenylalanine enter cells of Bacillus subtilis via a system of active transport that exhibits complex kinetic behavior. The specificity of the transport system was characterized both at low concentrations of transport substrate (where affinity for l-tyrosine or l-phenylalanine is high but capacity is low) and at high concentrations (where affinity is low but capacity is high). Specificity was not found to differ significantly as a function of either l tyrosine or l-phenylalanine concentration. Kinetic analysis showed that the relationship between the uptake of l-phenylalanine and l-tyrosine is strictly competitive. Neither l-tyrosine nor l-phenylalanine uptake was competitively inhibited by other naturally occurring l-amino acids, indicating the importance of the phenyl side chain to uptake specificity. Hence, it is concluded that l tyrosine and l-phenylalanine are transported by a common system that is specific for these two amino acids. The abilities of analogue derivatives of l-tyrosine and l-phenylalanine to inhibit the uptake of l-[(14)C]tyrosine and l [(14)C]phenylalanine competitively were determined throughout a wide range of substrate and inhibitor concentrations. In this manner, the contributions of the side chain, the alpha-amino group and the carboxyl group to uptake specificity were established. It is concluded that the positively charged alpha-amino group contributes more significantly to uptake specificity than does the negatively charged carboxyl group. The recognition of a phenyl ring is an essential feature of specificity; other amino acids with aromatic side chains, such as the indole and imidazole rings of l-tryptophan and l-histidine, do not compete with l tyrosine and l-phenylalanine for uptake. The presence of the p-hydroxy substitutent in the side chain (as in l-tyrosine) enhances the uptake of the aryl amino acid analogues investigated. PMID- 4199138 TI - Ultrastructural studies of sporulation in a conditionally temperature-sensitive ribonucleic acid polymerase mutant of Bacillus subtilis. AB - Morphological studies of a conditionally temperature-sensitive ribonucleic acid polymerase mutant of Bacillus subtilis have revealed that sporulation is inhibited at stage II when the cells are grown at 47.5 C. Growth and sporulation occur normally at 30 C with the mutant. The mutant grows normally at 47.5 C but is prevented from sporulating at the nonpermissive temperature by an abnormal septation during forespore membrane formation which prevents the subsequent engulfment process (stage III). The mutation affects the normal functioning of ribonucleic acid polymerase at the nonpermissive temperature resulting in abortive sporulation. PMID- 4199139 TI - Soluble antigens associated with infection with apple chlorotic leaf spot virus. PMID- 4199140 TI - [Effect of calcium and zinc complexes of aminopolycarbonic acids on excretion and distribution of cadmium]. PMID- 4199141 TI - Dose distribution for cobalt 60 tangential irradiation of the breast and chest wall. PMID- 4199142 TI - Treatment of pain in chronic pancreatitis by irradiation. PMID- 4199143 TI - Cromolyn sodium in the management of the child with asthma: a symposium. Preliminary data from a collaborative group study. PMID- 4199144 TI - Experiences with cromolyn sodium in asthma in children. PMID- 4199145 TI - Reflections and thoughts on the use of cromolyn sodium in the asthmatic child. PMID- 4199146 TI - Personal observations on cromolyn sodium prophylaxis. PMID- 4199147 TI - Review and assessment of the efficacy of cromolyn sodium, particularly after long term administration. PMID- 4199148 TI - Pros and cons of cromolyn sodium prophylaxis. A summary of experiences with 70 asthmatic children. PMID- 4199150 TI - When a drug is the culprit. PMID- 4199149 TI - The new field of plastics toxicology--methods and results. PMID- 4199151 TI - Serologic characterization of a Malacosoma disstria Hubner (Lepidoptera: Lasiocampidae) cell line. PMID- 4199152 TI - Production of macrophage migration inhibition factors by virus-infected cell cultures. AB - Macrophage migration inhibitory (MIF-like) activity was demonstrated in the supernatant fluids from cultures of African green monkey kidney cells (BGM) infected with mumps virus or Newcastle disease virus. We could detect no such activity in noninfected cultures. The virus-induced activity reported here is not due to nonspecific cytotoxic material released by dead or dying cells, and it does not require cell replication for its production. Preliminary estimates of molecular weight by Sephadex G-100 chromatography revealed a broad band of activity associated with the 45,000 and 65,000 markers. These are significantly smaller than previously reported chemotactic substances from virus-infected cultures, and thus appear to represent different cell products. These MIF-like factors may be produced concomitantly with interferon. However, ultraviolet irradiation of appropriate duration abolishes the ability of viruses to induce substances with MIF-like activity while preserving the ability to induce interferon. This strongly suggests that interferon is not the agent responsible for the macrophage migration inhibition effect. The functional properties of these various cell products induced by virus infection suggest that they all may play a role in the response to virus infection in vivo. PMID- 4199153 TI - Immune response to Mycobacterium tuberculosis in rats. AB - After intravenous injection into rats, both the attenuated strain R1Rv and the virulent strain H37Rv of Mycobacterium tuberculosis grow in the liver and spleen. However, the infected rats mount a specific immune response with great rapidity, giving a false impression of natural resistance to the tubercle bacillus. Adoptive immunity to tuberculosis was achieved by transferring thoracic duct cells from immunized donors to normal syngeneic recipients. The transferred immunity was vested in a population of lymphocytes uncontaminated with macrophages. The adoptive immunity was effectively expressed against both attenuated and virulent tubercle bacilli, and it was shown to be immunologically specific. Lymphocytes which conferred immunity to tuberculosis were not protective against Listeria monocytogenes infection, and vice versa. Immunity could not be transferred with either normal thoracic duct lymphocytes (TDL), heat killed sensitized TDL, or serum from specifically immunized donors. The ability of TDL from BCG-immunized donors to confer immunity was maintained at an unimpaired level for at least 3 months after immunization. PMID- 4199154 TI - Extraction, purification, and chemical and immunological properties of the Streptococcus mutans group "a" polysaccharide cell wall antigen. AB - An antigen of Streptococcus mutans has been extracted from HS6 (group "a") whole cells and repeatedly fractionated by Sephadex chromatography. The antigen is shown to be a polysaccharide and contains the S. mutans group "a" antigenic site and also a second antigenic site which is common to "a" strains and 2 of 3 group "d" strains. Immunological electrophoretic and chromatographic data indicate that the two sites exist in a single molecule. The polysaccharide has a molecular weight of 107,000 and is composed of glucose, galactose, glucosamine, and galactosamine. No significant quantities of lipid, phosphorus, glycerol, or ribitol are present. Immunological specificity of the group "a" polysaccharide site depends primarily on a d-glucose . d-glucose sequence, the "a-d" site on a terminal d-galactose. Water at 100 C and pepsin (pH 2.5) at room temperature are very effective in extracting the polysaccharide from lyophilized S. mutans cells. Trypsin and lysozyme are less effective. The antigen-antibody combining site appears to be located at the cell wall surface. A small quantity of enzyme resistant protein (5%) is firmly linked to the antigen and is considered to be a remnant of a protein to which the polysaccharide is attached in the cell wall. The composition of the protein does not identify it as a part of the peptidoglycan. No reaction to the purified polysaccharide is obtained with antisera specific for teichoic acid glycerophosphate polymers from streptococci, staphylococci, or lactobacilli. PMID- 4199155 TI - Acute cavitary histoplasmosis in Rhesus monkeys: influence of immunological status. AB - Male rhesus monkeys were randomized into groups according to body weight, immunized with different Histoplasma capsulatum antigens, and two weeks later were infected intratracheally with 10(8)H. capsulatum yeast cells. Complement fixation antibody titers, skin tests, and chest X rays were performed at weekly intervals from immunization until autopsy, at which time the spleens were cultured and the lungs and other organs were dissected. Pulmonary cavities were found in 33% of the animals, and extrapulmonary dissemination was present in 85% of the animals. Delayed hypersensitivity and circulating antibody activity was detected in all animals at some time during the experimental period; however, animals which developed pulmonary cavities had a longer period before circulating antibodies were detected than animals which did not develop pulmonary cavities. Delayed hypersensitivity developed at approximately the same time in both cavitary and noncavitary animals. Early appearance of delayed hypersensitivity was associated with reduced amounts of extrapulmonary dissemination, in that animals with a later onset of skin test reactivity had more H. capsulatum cultured from the spleen. There was no correlation between the onset or titers of circulating antibodies and the spleen culture results. PMID- 4199156 TI - Immunofluorescent study of the replication of infectious pancreatic necrosis virus in trout and Atlantic salmon cell cultures. AB - Cell cultures of trout gonad tissue (RTG-2) and Atlantic salmon heart, kidney, liver, and spleen tissue were inoculated with 50 50% tissue culture infective doses (TCID(50)) of infectious pancreatic necrosis (IPN) virus per cell, and the titer of cell-associated and released virus was determined from 2 to 16 h postinoculation (PI). Cover slips were collected over the same period and stained for IPN viral antigen by the direct immunofluorescent (FA) technique. Viral replication was detected after a latent period of approximately 2 to 4 h and reached a peak titer of 10(8.2) to 10(8.4) TCID(50) per ml at 8 to 10 h PI. The release of virus was more rapid in Atlantic salmon cells than in RTG-2 cells. Viral antigen was first detected by FA from 3 to 4 h PI. Approximately 75 to 80% of the cells contained antigen in the cytoplasm 9 to 11 h PI. The direct FA technique was found to be a sensitive method for detecting IPN virus in infected cells. Three strains of IPN virus were tested for serological cross reactions by FA and virus neutralization tests. PMID- 4199157 TI - Pathogenesis of aleutian disease of mink: nature of the antiglobulin reaction and elution of antibody from erythrocytes and glomeruli of infected mink. AB - Erythrocytes from mink chronically infected with Aleutian disease virus (ADV) gave positive antiglobulin reactions with rabbit anti-mink immunoglobulin (Ig)G, anti-mink C3, and anti-mink serum, but did not react with anti-mink IgM. The strongest reaction was observed with anti-mink C3. Immunoelectrophoresis demonstrated that serum from rabbits injected with erythrocytes from ADV-infected mink gave a precipitin line with normal mink serum in the beta globulin region corresponding to C3. When normal mink erythrocytes were exposed to serum from ADV infected mink, they were not sensitized, demonstrating that the antibodies in these mink sera were not directed against erythrocyte antigens. Glycine hydrochloride buffer treatment of erythrocyte stromata and isolated glomeruli from ADV-infected mink yielded eluates containing serum proteins in the gamma globulin region which appeared to be IgG, and in the beta and alpha globulin regions which are probably complement components. In both erythrocyte and glomerular eluates, anti-ADV antibody was demonstrated. These findings suggested that the positive direct antiglobulin test and glomerulonephritis in Aleutian disease is due to the persistence of ADV and formation and deposition of ADV antigen-antibody-complement complexes on the erythrocyte surfaces and in glomerular capillaries. PMID- 4199158 TI - Hypogammaglobulinemia and thymic hypoplasia in horses: a primary combined immunodeficiency disorder. AB - A severe combined immunodeficiency disorder was demonstrated in two Arabian foals which were full siblings. The defect in the B-lymphocyte system was shown by hypogammaglobulinemia, lymphopenia, and absence of germinal centers. The almost total absence of thymic tissue in one foal and the lack of thymic dependent lymphocytes in the spleens of both foals demonstrate a T-lymphocyte defect. In a retrospective study of total available Arabian foal cases, 4 of 15 had evidence of immunodeficiency. PMID- 4199159 TI - An orthopantomographic study of prevalence of impacted teeth. PMID- 4199161 TI - Allogenic demineralized dentin implants in jaw defects of Java monkeys. PMID- 4199160 TI - Cellular fibrinolytic activity of human alveolar bone. PMID- 4199162 TI - A histologic study of experimentally induced radicular cysts. PMID- 4199163 TI - Modes of healing histologically after endodontic surgery in 70 cases. PMID- 4199164 TI - Correlation between histology and radiography in the assessment of healing after endodontic surgery. PMID- 4199165 TI - Maxillary sinus and surgical movement of maxilla. PMID- 4199166 TI - Age- and sex-dependence of the risk of intruding a root into the maxillary sinus. PMID- 4199167 TI - Antifibrinolytic effect of Apernyl in "dry socket". PMID- 4199168 TI - Radiographic criteria for the assessment of healing after endodontic surgery. PMID- 4199169 TI - A follow-up study of 1,000 cases treated by endodontic surgery. PMID- 4199170 TI - Cherubism. PMID- 4199171 TI - A histologic study of experimental oro-paranasal communications in monkeys. PMID- 4199172 TI - A multivariate analysis of the influence of various factors upon healing after endodontic surgery. PMID- 4199173 TI - A histobacteriologic study of dental and periapical structures after endodontic surgery. PMID- 4199174 TI - Quantitative PCB standards for electron capture gas chromatography. PMID- 4199175 TI - Cellular localization of carbonic anhydrase in avian tissues by labeled inhibitor autoradiography. PMID- 4199176 TI - Maltose in total parenteral nutrition of rats. PMID- 4199177 TI - Protein deficiency: contrasting effects on DNA and RNA metabolism in rat liver. PMID- 4199178 TI - Effect of dietary protein and magnesium on selected ATP phosphotransferases and neuromuscular behavior in young rats. PMID- 4199179 TI - Primate pulp response to an ultraviolet light cured restorative material. PMID- 4199180 TI - An autopsy case of leiomyosarcoma of the maxilla. PMID- 4199181 TI - Peripheral giant cell granulomas: an ultrastructural study of three lesions. PMID- 4199183 TI - The alpha cell in diabetic ketoacidosis. PMID- 4199182 TI - The pathogenesis of hydro-testis after ligation of the vas deferens: a study in several species. PMID- 4199184 TI - Medical abortion in South Australia. A critical assessment of early complications. PMID- 4199185 TI - [Prognosis of lymphogranulomatosis. Dependence on clinical stage of the disease, on histological type and on therapeutic procedure]. PMID- 4199186 TI - Neglect after cingulectomy. PMID- 4199187 TI - Cerebrospinal fluid levels of IgG, IgA and IgM in neurologic diseases. PMID- 4199188 TI - [Whole-body scintigraphy of the skeleton with various radionuclides]. PMID- 4199189 TI - The release of TSH from organ cultures of human fetal pituitary glands. PMID- 4199190 TI - The effect of calcitonin on glucose assimilation and insulin secretion in man. PMID- 4199191 TI - 16Alpha-hydroxylase activity in uterine tissue of the rhesus monkey. PMID- 4199192 TI - The time course of recombination of HCG subunits observed by immunological methods and circular dichroism studies. PMID- 4199193 TI - Subcellular distribution of glucuronyltransferase and its relevance for the enterohepatic circulation of oestrogens. PMID- 4199194 TI - Phonophoresis as a new method for perfusion of the ovary in vivo. PMID- 4199195 TI - Aromatization of 3H-pregnenolone sulfate in the rhesus monkey liver in vivo. PMID- 4199196 TI - The application of synthetic LRF and TRF in a combined function test in patients with pituitary tumors. PMID- 4199197 TI - Mitochondria and chloroplasts revisited. PMID- 4199198 TI - Perforation in acquired diverticular disease of the terminal ileum. PMID- 4199199 TI - [Problems in the determination of susceptibility of bacteria using the agar diffusion test. Correlation statistics and construction of a decisive procedure]. PMID- 4199200 TI - [Susceptibility of Pseudomonas aeruginosa to gentamicin, carbenicillin and framycetin]. PMID- 4199201 TI - [Studies on the metabolism of sodium cyclohexylsulfamate. II. In vitro conversion of sodium cyclohexylsulfamate to cyclohexylamine in livers of monkey, rabbit, guinea pig and rat]. PMID- 4199202 TI - [Establishment of the genetic transformation system from tryptophan auxotrophy to protorophy in Bacillus subtilis 168]. PMID- 4199203 TI - Thymus dependency of cells involved in transfer of delayed hypersensitivity to Listeria monocytogenes in mice. PMID- 4199204 TI - Reversal by the MER tubercle bacillus fraction of the suppressive effects of heterologous antilymphocytic serum (ALS) on the allograft reactivity of mice. PMID- 4199205 TI - A review of the development of the health services of Rhodesia from 1923 to the present day. PMID- 4199206 TI - [Problem of reduced resistance of various Neisseria gonorrhoeae strains to antibiotics]. PMID- 4199207 TI - [Glutaraldehyde in the treatment of hyperhydrosis of the feet]. PMID- 4199208 TI - [Phytodermatoses caused by Cyanophyta and Algae]. PMID- 4199209 TI - Limbic projections to the thalamus. PMID- 4199210 TI - [Selection model for the Rhesus blood-group system]. PMID- 4199211 TI - Genotype and phenotype in human chromosome aberrations and in the minute mutants of Drosophila melanogaster. PMID- 4199212 TI - [Hyperalimentation via intravenous route]. PMID- 4199213 TI - Pharmacology of cefazolin in human volunteers. PMID- 4199214 TI - Liver enzyme induction by anticonvulsant drugs, and its relationship to disturbed calcium and folic acid metabolism. PMID- 4199215 TI - Syntheses and biological activities of 7-ethyl-8-chloro-10-(1'-D-ribityl) isoalloxazine and 7-chloro-8-ethyl-10(1'-D-ribityl) isoalloxazine, analogs of riboflavin. PMID- 4199216 TI - Antiasthma agents. 1. 4-Oxo-4H-(1) benzothieno-(3,2-b)pyran-2-carboxylic acid and 4-oxo-4H-(1)benzofuro(3,2-b)pyran-2-carboxylic acid. PMID- 4199217 TI - Antiparasitic nitroimidazoles. 7. Some 4- and 5-styrylnitroimidazoles. PMID- 4199218 TI - Ouabain-dependent potassium-potassium exchange in the toad bladder. PMID- 4199220 TI - Transformation in Bacillus subtilis. Fate of newly introduced transforming DNA. PMID- 4199222 TI - [Treatment of children with hyaline membrane syndrome]. PMID- 4199221 TI - Morphological abnormalities of fungi induced by volatile microbial metabolites. PMID- 4199223 TI - Nursing care study: twins in Papua. PMID- 4199224 TI - [Studies on wild reservoirs and vectors of Trypanosoma cruzi. LI. Natural infection of the mustelid, Eira barbara barbara (Lin., 1758) by T. cruzi]. PMID- 4199225 TI - Phototaxis and sensory transduction in Euglena. AB - The accumulation of Euglena gracilis in an illuminated region is brought about by two main mechanisms: orientation and subsequent directed movement (positive phototaxis) toward light scattered from particles in the illuminated zone; and by the trapping of cells in this region because of shock reactions experienced upon the cells encountering a sudden decrease of light intensity at the light-dark boundary (inverse photophobic responses). Phototactic orientation is mediated by inverse photophobic reactions which occur when the shadow of the stigma periodically falls upon the photoreceptor proper. Euglena also exhibits shock reactions when an already high light intensity is increased further (direct photophobic responses). The expression of both types of phobic responses depends upon stimulus intensity and adaptation of the sensory system in a seemingly complex way. A definition of the minimum components of the stimulus transduction system and a systems analytical approach to the study of input-output relationships enables one to construct an electronic analog of the cell's signal processing system that converts the photoreceptor input to commands which activate or inhibit flagellar reorientation. Computer simulation studies show that this model has considerable predictive value. It is hoped that with the approach presented in this article, a generalized model has become available for dealing with the questions of sensory transduction in aneural systems. Certainly, at this point more questions have been raised than have been answered. Where is the processing device located? Are its kinetic properties determined by electrical processes or by the rates of chemical reactions? Is the processor, and thereby the behavior of the orgamism, modulated by natural environmental parameters, and can it be modified permanently through more drastic chemical treatment of the cell? Is the system capable of permanent or transitory modification through repeated response, that is, does it exhibit phenomena analogous to learning and memory in higher organisms? These are only a few of the problems that require study in the future. PMID- 4199226 TI - Phenocopies of pigmentary and behavioral effects of the yellow mutant in Drosophila induced by alpha-dimethyltyrosine. AB - alpha-Dimethyltyrosine induces a phenocopy of the body color mutant yellow when fed to larvae of Drosophila melanogaster. The compound also induces changes in male courtship behavior which are similar to the effects of the mutant gene. PMID- 4199227 TI - Effects of aminoglutethimide (Elipten Ciba), a steroid biosynthesis blocking agent, on adrenal glands in Cushing's syndrome. PMID- 4199228 TI - Osteocytes in chronic uremia. Differential count of osteocytes in human femoral bone. PMID- 4199229 TI - Infantile neurological Gaucher's disease in three siblings. An ultrastructural study. PMID- 4199231 TI - [Pathomorphology of the so-called epinephrine myocarditis. Light and electron microscopy studies]. PMID- 4199230 TI - [Sialadenosis of the parotid gland after long-term treatment with antihypertensive agents (Guanacline). Ultrastructural alterations]. PMID- 4199232 TI - [Morphological studies of the pancreas of rats in potassium deficiency, with special reference to the Islets of Langerhans]. PMID- 4199233 TI - [Levels of serum immunoglobulins of the main groups in patients with Bechterew's disease]. PMID- 4199234 TI - Ultrastructural changes in the superficial layers of the superior colliculus in Galago crassicaudatus (primates) after eye enucleation. PMID- 4199235 TI - [Liver function tests following long-term intake of oral contraceptives]. PMID- 4199236 TI - [Binding of some antibiotics by blood serum proteins]. PMID- 4199237 TI - Impaired delayed hypersensitivity in juvenile rheumatoid arthritis. PMID- 4199238 TI - Factors influencing biometric potency assays of brucella allergens in guinea pigs. PMID- 4199239 TI - The role of polymorphonuclear leucocytes in protecting mice vaccinated against Pseudomon as aeruginosa infections. PMID- 4199240 TI - Morquio-Brailsford disease. A report of four affected sisters with absence of excessive keratan sulphate in the urine. PMID- 4199241 TI - Spondylometaphyseal dysplasia. PMID- 4199242 TI - Treatment of ano-rectal gonorrhoea with ampicillin. PMID- 4199243 TI - T-strain mycoplasma isolation and serology in women. PMID- 4199244 TI - Analgesics and asthma. PMID- 4199245 TI - Thyrotrophin-releasing hormone in use. PMID- 4199246 TI - Long-term domiciliary oxygen in chronic bronchitis with pulmonary hypertension. AB - Five patients with chronic bronchitis and pulmonary hypertension were treated with oxygen in their homes for periods of between 6 and 24 months. Oxygen was supplied for 15 hours daily from cylinders or from an oxygen concentrator and few practical difficulties arose. After 23 to 59 weeks of treatment there were significant decreases in pulmonary arterial pressure and vascular resistance, and four of the five patients no longer had pulmonary hypertension at rest. Two of these patients had shown little response after three weeks of treatment. There was a reduction in the number of episodes of congestive cardiac failure compared with the corresponding period before treatment. Two of the patients improved enough to return to work. These results are encouraging enough to justify a controlled trial of the treatment in a large number of patients. PMID- 4199247 TI - Topical disodium cromoglycate. PMID- 4199248 TI - [Problems raised by detection of Australia antigen and of corresponding antibody in patients and blood donors]. PMID- 4199249 TI - Mortality in protein calorie malnutrition. PMID- 4199250 TI - Endotracheal gentamicin for the prevention of bronchial infections in patients with tracheotomy. PMID- 4199251 TI - [Kidney function during therapy of hypertension]. PMID- 4199252 TI - [Correlation of agar diffusion tests and serial dilution tests. Demonstration of regression lines for gentamycin]. PMID- 4199253 TI - Electron microscopy of Sarcocystis sp.: cyst wall, micropore, rhoptries, and an unidentified body. PMID- 4199254 TI - Enzyme levels in cercariae and adult Schistosoma mansoni. PMID- 4199255 TI - The stability and fractionation of malarial antigens from the blood of Africans infected with Plasmodium falciparum. PMID- 4199256 TI - The turnover of folate coenzymes in murine lymphoma cells. PMID- 4199257 TI - The proteolytic enzymes of the K-1 strain of Streptomyces griseus obtained from a commercial preparation (Pronase). Purification and characterization of the aminopeptidases. PMID- 4199258 TI - Biological mechanisms involved in the formation of deoxy sugars. VII. Biosynthesis of 6-deoxy-L-talose. PMID- 4199259 TI - The kinetics of dissociation of Cu2+-bovine serum albumin biuret complexes. PMID- 4199260 TI - Purification and properties of the sigma subunit of ribonucleic acid polymerase from vegetative Bacillus subtilis. PMID- 4199261 TI - Comparative size and properties of the sigma subunits of ribonucleic acid polymerase from Bacillus subtilis and Escherichia coli. PMID- 4199262 TI - Effects of thyrotropin-releasing hormone and hydrocortisone on synthesis and degradation of prolactin in a rat pituitary cell strain. PMID- 4199263 TI - In vitro synthesis of ribosomal ribonucleic acid by a deoxyribonucleic acid protein complex isolated from Escherichia coli. PMID- 4199264 TI - A human left ventricular control system model for cardiac diagnosis. PMID- 4199265 TI - Pattern variability in microtubular arrays associated with the tentacles of Actinobolina (Ciliatea: Gymnostomatida). PMID- 4199266 TI - Ultracytochemical observations of glycogen synthesis and storage during infradian growth of Tetrahymena pyriformis. PMID- 4199267 TI - Chemistry of releasing hormones. PMID- 4199268 TI - Thyrotrophin releasing hormone and thyroid function. PMID- 4199269 TI - Pathogenic lactobacilli. PMID- 4199270 TI - Gonococcal enhancement of staphylococcal virulence for the mouse. PMID- 4199271 TI - Synergism between beta-lactam antibiotics: a test of theoretical predictions made with Staphylococcus aureus. PMID- 4199272 TI - Unstable resistance to methicillin in Staphylococcus epidermidis. PMID- 4199273 TI - An immunodiffusion analysis of strains of Mycobacterium ulcerans isolated in Australia, Malaya, Mexico, Uganda and Zaire. PMID- 4199274 TI - Pyocine typing of mucoid strains of Pseudomonas aeruginosa isolated from children with cystic fibrosis. PMID- 4199275 TI - Quantitative study of P substance in the megaesophagus and megacolon of human Trypanosoma cruzi infections. PMID- 4199276 TI - The isolation of micro-organisms from creams and ointments by membrane filtration. PMID- 4199277 TI - Observations of the mechanism of action of the sulfonylureas under clinical conditions. PMID- 4199278 TI - Black piedra among Brazilian Indians. PMID- 4199279 TI - [Comparative study between the hemagglutination test and the complement fixation test in the pericardial fluid of patients with Chagas' disease]. PMID- 4199280 TI - [Specific immunoglobulins (IgA, IgG, and IgM) in serum of patients with chronic Chagas' disease analyzed by indirect immunofluorescence reactions]. PMID- 4199281 TI - Hemagglutination with preserved, sensitized cells, a practical test for routine serologic diagnosis of American trypanosomiasis. PMID- 4199282 TI - Premature births in California sea lions: association with high organochlorine pollutant residue levels. AB - Premature pupping in California sea lions has been noted on the breeding islands since 1968. Organochlorine pesticides and polychlorinated biphenyl residues were two to eight times higher in tissues of premature parturient females and pups than in similar tissues of full-term parturient females and pups collected on San Miguel Island in 1970. PMID- 4199283 TI - Cell-mediated immune responses in vitro: interaction of thymus-derived cells during cytotoxic allograft responses in vitro. AB - A mouse in vitro allograft system was used to check for synergism among thymus derived cells during cell-mediated immune responses. Synergistic interactions occurred between thymus and thymus-derived lymphocytes. The majority of precursors of cytotoxic effector cells were peripheral thymus-derived cells; thymocytes acted mainly as amplifier cells. PMID- 4199285 TI - Behavior of free-ranging macaques after intraventricular 6-hydroxydopamine. AB - Macaques (Macaca mulatta) observed in a free-ranging colony on Guayacan Island, Puerto Rico, were significantly different in their social interactions, initiatives, facial expressions, and postures after intraventricular 6 hydroxydopamine compared with sham-treated and field controls. This study extends the known effects of 6-hydroxydopamine and catecholamine depletion to the social interactions of a higher primate species under free-ranging conditions. PMID- 4199284 TI - Biosynthesis of a vasotocin-like peptide in cell cultures from pineal glands of human fetuses. AB - Cultured cells from pineal glands of human fetuses release into their media a substance that has antidiuretic and hydroosmotic activities. The ratio of these activities as well as their susceptibility to tryptic digestion, specific oxidative inactivation by tyrosinase, and reductive inactivation by sodium thioglycollate, indicates the presence of a basic peptide, presumably identical with arginine vasotocin. The total amount of this peptide released into the culture media during 38 days of incubation is about ten times greater than the amount contained in nonincubated pineal glands from fetuses of the same age, strongly suggesting that fetal ependymal cells from the pineal gland can synthesize in vitro a peptide similar to arginine vasotocin. PMID- 4199286 TI - Studies in actinomycetes in Egyptian soils. II. The occurrence of antibiotic producing actinomycetes. PMID- 4199287 TI - [The microflora and aflatoxin B1 amount of groundnut samples]. PMID- 4199288 TI - Antimicrobial principles in leaves of Lawsonia inermis L. PMID- 4199289 TI - Production of candicidin by Streptomyces griseus. PMID- 4199290 TI - Arterial CO2, O2, pH, and HCO3- values of ectotherms living in the Amazon. PMID- 4199291 TI - The distribution of manual asymmetry. PMID- 4199292 TI - [Occurrence of Australia antigen in various groups in Senegal]. PMID- 4199293 TI - [Antiobiotic sensitivity of tubercular bacilli recently isolated in Dakar]. PMID- 4199294 TI - [Anoxic convulsions and epilepsy (2 cases of convulsive syncope)]. PMID- 4199295 TI - [Antibiotic sensitivity of 100 strains of Pseudomonas aeruginosa isolated at Dakar]. PMID- 4199296 TI - Discordant response to nitroglycerin of strain gauge arch and maximum rate of rise of left ventricular pressure in dogs. PMID- 4199297 TI - [Critical evaluation in the clinic of the so-called "nonspecific reactive lymphadenitis"]. PMID- 4199298 TI - [New outline of combination chemotherapy in the treatment of developed malignant granuloma: preliminary study of a possible use of adriamycin]. PMID- 4199299 TI - [Splenectomy in the therapy of Hodgkin's lymphoma]. PMID- 4199300 TI - [Use of total radiotherapy in Hodgkin's lymphoma]. PMID- 4199301 TI - [Mechanism of splenic involvement in Hodgkin's lymphoma]. PMID- 4199302 TI - [Selective celiac-splenic arteriography in determination of the stage of Hodgkin's lymphoma]. PMID- 4199303 TI - [Diagnosis of hepatic localization of Hodgkin's lymphoma]. PMID- 4199304 TI - [Preliminary studies on the immunoreactivity of splenectomized patients with malignant granuloma]. PMID- 4199305 TI - [Delayed sensitivity in Hodgkin's disease]. PMID- 4199306 TI - [Membrane immunoglobulins in peripheral blood lymphocytes in Hodgkin's disease]. PMID- 4199307 TI - [Cytoferometry in Hodgkin's disease]. PMID- 4199308 TI - [Polychemotherapy of Hodgkin's lymphoma. 3. Stage IV]. PMID- 4199310 TI - [Blastogenesis and activation of beta-glucuronidase in cultured lymphocytes from children with Hodgkin's disease and their blood relatives. Possible interference of genetic factors in the etiopathogenesis of the disease]. PMID- 4199309 TI - [Determination of alkaline phosphatase isoenzymes in the definition of the clinical stage of Hodgkin's disease]. PMID- 4199311 TI - [Lymphocyte transformation caused by PHA and PPD in patients with Hodgkin's disease and its correlation with clinical and hematological aspects]. PMID- 4199312 TI - [Radioisotope study of Hodgkin's desease with special reference to the morphological and functional aspects of the spleen]. PMID- 4199313 TI - [Lymphadenographic and histopathological comparison of lumbo-aortic lymph nodes in Hodgkin's lymphoma]. PMID- 4199314 TI - [Immunofluoroscopy in cryoglobulinemias. Preliminary data]. PMID- 4199315 TI - [Dyserythropoietic congenital anemia. Hematological and chromosomal study of a case]. PMID- 4199316 TI - [Relationship between bone marrow activation and toxicity of antineoplastic agents]. PMID- 4199317 TI - Alcoholism as a predictive index of elapsed time between grand mal seizures. PMID- 4199318 TI - Asymmetric bidirectional replication of Bacillus subtilis chromosome. PMID- 4199319 TI - Topography of chromosome membrane junction in Bacillus subtilis. PMID- 4199320 TI - Mapping genes for the ribosomal protein of Drosophila. PMID- 4199321 TI - [Para-articular ossifications and calcifications following burns: review of the literature and presentation of 3 cases]. PMID- 4199322 TI - [Effectiveness of treating bees for paratyphoid]. PMID- 4199323 TI - [Zinc concentration in the rat hair in zinc depletion and repletion. Suitability of the hair as an indicator of zinc distribution]. PMID- 4199324 TI - The hypocalcemic effect of protamine in goats and sheep. PMID- 4199325 TI - [The fatty liver problem in the laying hen. I. Effect of high energy and restrictive feeding on body weight, production, blood lipid level, and total lipid content of the liver in caged hens at the beginning of the laying period]. PMID- 4199326 TI - [The fatty liver problem in the laying hen. II. Rate of synthesis and oxidation of fatty acids and quotient of glutathione in the liver of laying hens fed conventionally and restrictively]. PMID- 4199327 TI - The effect of spironolactone on the mercury content of various organs of rats given methyl mercury. PMID- 4199328 TI - [Elimination, plasma protein binding, and dosage of some sulfonamides. II. Studies in cattle]. PMID- 4199329 TI - [Elimination, plasma protein binding and dosage of some sulfonamides. 3. Studies inn swine]. PMID- 4199330 TI - Changes in leucocyte distribution associated with age in thoroughbred horses. PMID- 4199331 TI - [The neuroepithelial invagination, a form of the retinal dysplasia in the Beagle]. PMID- 4199332 TI - Integration of mutagenicity studies into toxicity tests. PMID- 4199333 TI - New formaldehyde base disinfectants. AB - Preparations of formaldehyde in various organic liquids-ethylene glycol, glycerol, and propylene glycol-serve as effective disinfectants towards microbial vegetative cells and spores. This disinfection is a temperature-dependent process and is manifest when these formaldehyde base disinfectants are dissolved in water. The irritating vapors associated with formaldehyde disinfection are not present in either of these new formaldehyde base disinfectants or in aqueous solutions of them. PMID- 4199334 TI - Simplified method for producing pyocins from Pseudomonas aeruginosa. AB - Good yields of pyocin are obtained when Pseudomonas aeruginosa is grown in Trypticase soy broth (without glucose) (BBL) plus 1% potassium nitrate. As a result, pyocin production for routine epidemiological typing can be done in screw cap tubes, without mechanical agitation or mitomycin C induction. PMID- 4199335 TI - Volatile compounds produced in sterile fish muscle (Sebastes melanops) by Pseudomonas putrefaciens, Pseudomonas fluorescens, and an Achromobacter species. AB - Volatile compounds produced by Pseudomonas putrefaciens, P. fluorescens, and an Achromobacter species in sterile fish muscle (Sebastes melanops) were identified by combined gas-liquid chromatography and mass spectrometry. Compounds produced by P. putrefaciens included methyl mercaptan, dimethyl disulfide, dimethyl trisulfide, 3-methyl-1-butanol, and trimethylamine. With the exception of dimethyl trisulfide, the same compounds were produced by an Achromobacter species. Methyl mercaptan and dimethyl disulfide were the major sulfur-containing compounds produced by P. fluorescens. PMID- 4199336 TI - Preparation, sensitivity, and specificity of Limulus lysate for endotoxin assay. AB - Limulus amoebocyte lysate was prepared from a total of 180 crabs during 1971 and 1972 by using a slightly modified lysate preparation procedure. Marked variability of lysate potency was noted both years. In addition, lysate quality appeared diminished in 1972 as compared with 1971. Different lysate batches were evaluated for potency by using a variety of endotoxin preparations. Variations in batch potencies were observed, but little variation in reactivity among different endotoxin preparations was noted. Use of potent lysate batches allowed detection of endotoxin concentrations as low as 100 pg/ml. No endotoxinlike activity was observed from 11 different strains of yeast by use of the Limulus assay. PMID- 4199337 TI - Stimulation of lactic acid bacteria by a micrococcus isolate: evidence for multiple effects. AB - Growth of, and rate of acid production by, six cultures of lactic acid bacteria were increased in the presence of Micrococcus isolate F4 or a preparation of its capsular material. Concentrations of hydrogen peroxide found in pure cultures of the lactic acid bacteria were not detectable, or were greatly reduced, in mixed culture with Micrococcus isolate F4. The capsular material was not as effective as whole cells in preventing accumulation of H(2)O(2). Catalase stimulated growth of, and the rate of acid production by, the lactic acid bacteria, but not to the same extent as Micrococcus isolate F4 in some cultures. The existence of two mechanisms for micrococcal stimulation of the lactic acid bacteria is postulated. One mechanism involves removal of H(2)O(2); the other has not been characterized. PMID- 4199338 TI - Comparative evaluation of five serological methods for the diagnosis of sporotrichosis. AB - The diagnosis of sporotrichosis can be time consuming. Serological procedures could facilitate the rapid and accurate diagnosis of this disease. A slide latex agglutination (SLA) test for sporotrichosis was developed and compared with the tube agglutination (TA), complement fixation (CF), and immunodiffusion (ID) tests in the serological study of 80 proven human cases of sporotrichosis representing the cutaneous, subcutaneous, and extracutaneous forms of the disease. In addition, the indirect fluorescent antibody (IFA) technique was applied to 61 case sera. In the SLA test, latex particles sensitized with culture filtrate antigens from the yeast form of Sporothrix schenckii (B 959) detected 94% of the cases, as compared to 96% of the cases detected by the TA test, 68% by the CF test, and 56% by the ID test. The IFA test detected 90% of the 61 cases. The SLA and ID tests were specific, showing no reactions with sera from 86 persons with no disease or with diseases other than sporotrichosis. Because of its sensitivity, specificity, ease of performance, and ability to provide results in 5 min, the SLA test is highly recommended for routine use in the clinical laboratory. PMID- 4199339 TI - Biomagnification of p, p'-DDT and methoxychlor by bacteria. AB - Aerobacter aerogenes and Bacillus subtilis accumulated p, p'-DDT and methoxychlor directly from water. Uptake of both (14)C-labeled organochlorine insecticides was rapid; 80 to 90% of the 24-h residues were reached within 30 min. Total cellular residues varied linearly with concentrations of DDT and methoxychlor in water ranging from 0.5 to 5.0 mug/liter. The residue magnification factors from water were between 1,400- to 4,300-fold, but were independent of insecticide concentrations in water. When the insecticide-exposed microbial cells were washed with pesticide-free water, DDT residues were 45% in A. aerogenes and 30% in B. subtilis, whereas the methoxychlor level decreased nearly 75% in both organisms. Subsequent washing did not further reduce the insecticide residue. Autoclave killed bacteria also rapidly adsorbed DDT and methoxychlor from water and, in some instances, residues were higher than in the living cells. Molecular polarity and lipid solubility appear to influence the retention of the organochlorine insecticides by bacterial cells. PMID- 4199340 TI - Characterization of mild thermal stress in Pseudomonas fluorescens and its repair. AB - The exposure of exponentially growing Pseudomonas fluorescens P7 cells to heating at 36 C for 2 h in a defined medium, followed by cooling to 25 C and further incubation at this, the optimal growth temperature, resulted in the apparent death of approximately 99% of the cells, as determined by their inability to form colonies on Trypticase soy agar. Continued incubation at 25 C resulted in an extremely rapid increase in the Trypticase soy agar count, demonstrating that the phenomenon observed was not death but rather injury. Presumptive evidence of heat stimulated ribonucleic acid (RNA) degradation and membrane damage was provided by the observed loss of 260-nm absorbing materials. Confirmation of RNA degradation was obtained by colorimetric analysis. Ribosomal RNA from normal and injured cells, which was electrophoretically separated on polyacrylamide gels, revealed that the 23S and 16S species were only partially destroyed. Inhibitor studies demonstrated, however, that RNA synthesis was necessary for recovery. The unusual accumulation of 17S RNA during recovery pointed to the presence of a heat-induced lesion in the RNA maturation process. A thermally induced membrane lesion is also discussed. PMID- 4199341 TI - Differential counting in mixed cultures with coulter counters. AB - A critical comparison of Coulter, viable, and microscope counts for several mixed cultures of microorganisms has been made. This investigation shows that Coulter counting can provide reliable estimates of microbial numbers in mixed cultures. Precautions and limitations of Coulter counting in mixed cultures are discussed. PMID- 4199342 TI - Insulin degradation. V. Unmasking of glutathione-insulin transhydrogenase in rat liver microsomal membrane. PMID- 4199343 TI - Tritium incorporation and retention in photosynthesizing algae. PMID- 4199344 TI - Physical-chemical properties of stable yeast ribosomes and ribosomal subunits. PMID- 4199345 TI - Transcription during cell differentiation in Naegleria gruberi. Preferential synthesis of messenger RNA. PMID- 4199346 TI - Studies on bovine pancreatic deoxyribonuclease A. I. General properties and activation with different bivalent metals. PMID- 4199347 TI - Trace elements and skin pigmentation. PMID- 4199348 TI - Quantitative haemagglutination. 4. Effect of neuraminidase treatment on agglutination by blood group antibodies. PMID- 4199349 TI - Hyperamylasaemia in diabetic ketosis. PMID- 4199350 TI - Significance of Pseudomonas aeruginosa in sputum. PMID- 4199351 TI - Pyogenic vertebral osteomyelitis in heroin addicts. AB - The diagnosis of pyogenic vertebral osteomyelitis was made in seven narcotic addicts between 1967 and 1972. Vertebrae involved were either cervical or lumbar. Bacteriologic diagnosis was made in each case by percutaneous needle biopsy and aspiration. Staphylococcus aureus was cultured in two patients. Five patients had infections due to Gram-negative bacteria, including Klebsiella pneumoniae, Pseudomonas aeruginosa and Enterobacter. All patients were cured by treatment with antibiotics and immobilization. PMID- 4199352 TI - Radioprotection of tumor and normal tissues by thiophosphate compounds. PMID- 4199353 TI - Inactivation of cultured human cells and control of C3H mouse mammary tumors with accelerated nitrogen ions. PMID- 4199354 TI - Growth retardation in children after megavoltage irradiation of the spine. PMID- 4199355 TI - Results of regional radiotherapy in localized Hodgkin's disease in children. PMID- 4199356 TI - Radiation therapy in the treatment of childhood astrocytic gliomas. PMID- 4199357 TI - [Time sequential changes of biochemical parameters in experimental calorie protein malnutrition in the rat]. PMID- 4199358 TI - [Long-term tube feeding]. PMID- 4199359 TI - [The pathophysiology of ischemic cerebrovascular disorders]. PMID- 4199360 TI - An automated microbiological method for the measurement of vitamin B12. AB - An automated method for the microbiological assay of vitamin B(12) is described. A chloramphenicol-resistant strain of Lactobacillus leichmannii is used as the test organism and this eliminates the need for sterilization or aseptic addition. Precipitation of the serum protein is avoided by dilution of the serum with a glutamic/malic acid solution before heating the preparation to free the vitamin B(12). Tests can be set up at a rate of 80 an hour and after incubation they can be read at 160 an hour. By interfacing a programmed electronic calculator directly with the Mecolab M which is used for the assays, results are printed directly in ng/l. PMID- 4199361 TI - Early detection of influenza virus in cell culture by means of immunofluorescence. AB - An indirect fluorescent antibody technique using human serum for the rapid detection of influenza A virus in monkey kidney cell cultures is described. Influenza A2 virus was isolated from 38 of 88 nose/throat swabs received from patients with suspected influenza during the winter of 1971-72.Thirty-two strains isolated in monkey kidney cell cultures were identified by immunofluorescence on the day haemadsorption was observed, 22 of them within a week of receipt of the specimen. Human antiserum was found to be very satisfactory for this purpose. PMID- 4199362 TI - A rapid assay method for cephalosporins. AB - A simple, rapid assay for cephalosporins is described. The method is based on the inhibition by cephalosporins of the fermentation of glucose or inositol by a strain of Providence resistant to aminoglycoside antibiotics. The method gives answers which are as accurate as those obtained by standard agar diffusion techniques within four hours, and utilizes skills and resources readily available in most routine bacteriology departments. Results are not affected by gentamicin or kanamycin concurrently administered to the patient. This method will be of value in helping to monitor cephalosporin therapy in patients with serious sepsis, especially those with impaired renal function, and may help in elucidating and preventing the problem of nephrotoxicity associated with cephalosporin administration. PMID- 4199364 TI - The development of aluminum containers for the storage of blood in liquid nitrogen for the immunization of Rh volunteers. PMID- 4199363 TI - Antithrombin-3 deficiency in a Dutch family. AB - A Dutch family (family A) with inherited antithrombin-III deficiency and an increased incidence of venous thrombosis was investigated. Antithrombin-III levels were measured by means of a coagulation assay in plasma and by single radial immunodiffusion in plasma and serum.THREE GROUPS COULD BE DISTINGUISHED: group I comprised the relations-in-law of family A, group II the members of family A with a plasma antithrombin-III level higher than 90% of normal, when determined by the immunoassay, and group III the members of family A with an antithrombin-III level of less than 60%. To group III belonged all eight adults with an abnormal tendency to thrombosis, and furthermore nine children, all having a parent with abnormally low antithrombin-III levels. Mean plasma and serum antithrombin-III levels were significantly decreased in group III. However, the results of the coagulation assay showed some overlap between groups II and III. In addition, the immunoassay appeared to be much less laborious than the coagulation assay. Therefore, the former assay is recommended in any search for similar families. The results of our family investigation confirm the findings of Egeberg (1965) that inherited antithrombin-III deficiency, giving rise to plasma levels between 50 and 60% of normal, causes thrombophilia and that the pattern of inheritance is autosomal dominant. PMID- 4199365 TI - Alternation behaviour in the rhesus monkey after profound hypoxia. PMID- 4199366 TI - Relationships between luminance and visual acuity in the rhesus monkey. AB - 1. The ability of rhesus monkeys to detect the gap in Landolt ring test-objects that were presented against background luminances between 5 x 10(-5) cd/m(2) and 5 x 10(3) cd/m(2) was compared with similar human data.2. At high luminance levels the acuity of human observers is slightly better than that of rhesus, but rhesus have better acuity at scotopic luminance-levels. Both species have distinct photopic and scotopic acuity functions that cross at 6 x 10(-3) cd/m(2).3. The threshold for light detection is estimated to be the same for both species when specified in quanta incident on the retina.4. It is concluded that the receptor and neural mechanisms that mediate visual-acuity function similarly in rhesus and man, and that the differences in acuity that were measured in the two species may be attributed to optical rather than to physiological factors. PMID- 4199368 TI - Serum sodium and potassium and blood glucose levels in cynamolgus monkeys after administration of melatonin. PMID- 4199369 TI - Antigens of the male tract. PMID- 4199367 TI - Potassium accumulation in smooth muscle and associated ultrastructural changes. AB - 1. The water content, extracellular ((60)CoEDTA) space, ionic composition and ultrastructure of several mammalian smooth muscles were studied after incubation in solutions of varying ionic compositions and osmolarities.2. Substitution of KCl for NaCl resulted in an increase in cell water, K and Cl, accompanied by little change in total wet weight. This was due to a reduction in the extracellular space.3. Changes in extracellular osmolarity produced a wider range of cell volumes in high KCl solutions than in Krebs. The addition of 29-58 mM sucrose to high KCl prevented the swelling.4. Electron microscopy of smooth muscle swollen in high KCl solution revealed light (less electron opaque than normal) fibres of increased diameter, reduction in extracellular space, and nuclear swelling. The normal thick filament lattice was destroyed in swollen, osmium-fixed smooth muscles.5. The ultrastructural changes ascribed to swelling were absent in smooth muscles, (a) depolarized in high K(2)SO(4) solutions, (b) in high KCl solutions with 29-58 mM sucrose, and (c) returned to normal Krebs solution for recovery from swelling.6. Smooth muscles incubated in high KCl (swollen) and high K(2)SO(4) (unswollen) exhibited similar contractile responses, suggesting the filament lattice was intact until fixation, and that the contractile mechanism can operate over a relatively wide range of actin to myosin separations.7. Shrinkage of smooth muscles in high KCl solutions made hypertonic with the addition of 10% sucrose was accompanied by an aggregation of the thick filaments.8. The cell water of fixed taenia coli was reduced (a) by incubation in hypertonic solution followed by fixation in normal glutaraldehyde, or (b) by fixation of normal tissue in hypertonic glutaraldehyde. Osmotic responses during aldehyde fixation may be a source of artifact in the visualization of the normal filament lattice. PMID- 4199371 TI - [Pneumonia during a course of subacute meningococcal sepsis]. PMID- 4199370 TI - Lead poisoning in small animals. PMID- 4199372 TI - [Disodium cromoglycate (Intal) in the treatment of bronchial asthma]. PMID- 4199373 TI - [Evidence of a responsible gene for the thermosensibility during laying-season with Drosophila melanogaster]. PMID- 4199374 TI - Infantile hemiplegic disorder. PMID- 4199375 TI - [Results of complex tuberculin-antibacterial treatment of patients with tuberculosis of the lungs]. PMID- 4199376 TI - [Experience with long-term application of ethambutol in ambulatory and hospitalized patients with chronic destructive tuberculosis of the lungs]. PMID- 4199377 TI - [Significance of delayed-type hypersensitivity in the immunity against tuberculous infection]. PMID- 4199378 TI - [Transplacental transmission of antituberculosis hemagglutinins in guinea pigs infected with tuberculosis and immunized with BCG]. PMID- 4199379 TI - [Esophageal diverticula]. PMID- 4199381 TI - Five cases of meningitis due to sulfonamide-resistant meningococci. PMID- 4199380 TI - Prolonged meningococcal septicemia. A report of four cases and a comparison with benign gonococcal septicemia. PMID- 4199382 TI - Fixation and inactivation of cholera toxin by GM1 ganglioside. PMID- 4199383 TI - [Diagnosis and differential diagnosis of tuberculosis of the locomotor organs (current criteria for classification)]. PMID- 4199384 TI - Effect of synthetic thyrotrophin-releasing factor on pituitary TSH secretion in normal subjects and patients with hypothalamic-pituitary disorders. PMID- 4199385 TI - Effect of thyrotrophin-releasing hormone on serum levels of pituitary hormones in men and women. PMID- 4199386 TI - Disodium cromoglycate in bronchial asthma. A double-blind trial in adult patients. PMID- 4199387 TI - Multiple myeloma with urinary excretion of heavy chain components of IgG and nodular glomerulosclerosis. PMID- 4199388 TI - The glomerular filtration rate during moderate hyperglycemia in normal man. PMID- 4199389 TI - Albuminuria in acute and chronic renal failure. PMID- 4199390 TI - Effect of incorporated 226Ra on colony forming units of bone marrow in splenectomized mice. PMID- 4199391 TI - Carcinoma of the vulva. Results of an individualized treatment schedule. PMID- 4199392 TI - Stress electrocardiography in the evaluation of aortocoronary bypass surgery. PMID- 4199393 TI - Tuberculoma of the heart. Report of 9 cases. PMID- 4199394 TI - The value of warning arrhythmias in the prediction of ventricular fibrillation within one hour of coronary occlusion. Experimental studies in the baboon. PMID- 4199395 TI - Metabolic studies on polychlorinated biphenyls. I. Metabolic fate of 3,4,3',4' tetrachlorobiphenyl in rats. PMID- 4199396 TI - [Lithium therapy of thyrotoxicosis. Clinical experiences and results with a new therapeutic principle]. PMID- 4199397 TI - [Quantitative changes of immunoglobulins (IgA, IgG, IgM) in chronic liver disease]. PMID- 4199398 TI - [Eyelid edemas, cryesthesia and decrease in vitality during long term lithium therapy]. PMID- 4199399 TI - [Kidney toxicity of analgesics]. PMID- 4199400 TI - The isolation of immunogenically pure IgM from Cohn fraction 3 of pooled normal human plasma. PMID- 4199401 TI - The association of the serum agglutinators with the fast IgG globulins. PMID- 4199402 TI - Immunological studies on HeLa cell heat-stable alkaline phosphatases and their antigenic relationship with human placental and intestinal isoenzymes. PMID- 4199403 TI - Sensitivity to reduction of human immunoglobulin G of different heavy chain sub classes. PMID- 4199404 TI - Studies on sheep anti-human IgG antibodies and their sub-units. PMID- 4199405 TI - The hydrolysis of rabbit immunoglobulin G with purified cathepsins D and E. PMID- 4199406 TI - Biochemical and immunological properties of low molecular weight constituents of Timothy pollen antigen. PMID- 4199407 TI - The effect of disodium cromoglycate and PGF2 alpha on acute cutaneous reactions of the guinea pig and rat. PMID- 4199408 TI - Studies on the inhibition of cellular anaphylaxis. PMID- 4199409 TI - Intrinsic activation of plasma kinin formation and complement. PMID- 4199410 TI - Cellular and physiologic studies of immediate-type respiratory reactions. PMID- 4199411 TI - Circulatory activity of a fully synthetic hydrogenated ergot alkaloid (DN 16 457). PMID- 4199412 TI - Defective mononuclear phagocyte function in patients with myelomonocytic leukemia and in some patients with lymphoma. AB - Mononuclear phagocytes from 8 of 10 patients with myelomonocytic leukemia and 2 of 9 patients with lymphoma phagocytized several species of bacteria but did not inhibit intracellular bacterial replication normally. Intracellular organisms were protected from the lethal effects of antibiotics in the medium. This defect of microbicidal function of malignant monocytes may explain in part the frequency of infection and the mechanism of antibiotic-resistant infection in some patients with malignant myeloproliferative and lymphoproliferative diseases. PMID- 4199413 TI - Studies on the nature of antihemophilic factor (factor VIII). Further evidence relating the AHF-like antigens in normal and hemophilic plasmas. AB - Normal human antihemophilic factor (AHF, factor VIII) and the protein antigenically related to it in hemophilic plasma both appeared in the void volume of columns of agarose (Sepharose 4B) during purification of these agents. On ultracentrifugation upon sucrose gradients, both agents had sedimentation characteristics similar to those of an S30 marker. After reduction, the polypeptide chains of purified normal AHF and of the nonfunctional agent from hemophilic patients had an apparent molecular weight of 200,000 as determined by sodium dodecyl sulfate polyacrylamide gel electrophoresis. These observations suggest that AHF, purified as described, exists as a large molecule with subunits of molecular weight of approximately 200,000. Antisera to normal AHF and the nonfunctional agent from hemophilic plasma appeared to be directed against antigens of similar electrophoretic mobility and precipitating characteristics, present in normal and hemophilic plasma but deficient in severe von Willebrand's disease plasma. Both antisera neutralized the AHF clot-promoting activity present in normal plasma, and this property was removed by absorption of the antisera with concentrates of normal or hemophilic plasma but to a greatly reduced extent by concentrates of von Willebrand's disease plasma. These findings suggest that the antigen detected in normal plasma by the antisera appears on a molecule participating in the AHF clot-promoting reaction. PMID- 4199414 TI - The subunit structure of normal and hemophilic factor VIII. AB - Human factor VIII from normals and hemophiliacs was partially purified by ethanol and polyethylene glycol precipitations. Final purification was achieved by gel filtration on 2 or 4% agarose or ion exchange chromatography on diethylaminoethyl cellulose. Comparable amounts of highly purified protein were obtained from normal and hemophilic plasma following the agarose chromatography step. Highly purified factor VIII was not dissociated by 6 M guanidine hydrochloride or 1% sodium dodecyl sulfate. However, when reduced by beta-mercaptoethanol and analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis, a single subunit species with an estimated 195,000 molecular weight was found for both normal and hemophilic factor VIII. By sedimentation equilibrium analysis, the normal factor VIII subunit was homogeneous and had an estimated molecular weight of 202,000. The subunit polypeptides from normal or hemophilic factor VIII contained carbohydrate. Each was homogeneous by isoelectric focusing. Immunodiffusion of purified normal and hemophilic factor VIII against rabbit antiserum to purified normal human factor VIII showed a single line of precipitation. Very low concentrations of purified human thrombin initially increased the activity of normal factor VIII about threefold and then progressively destroyed activity by 3 h. Only minimal activation occurred with hemophilic factor VIII. Both the activation and inactivation of normal and hemophilic factor VIII were unaccompanied by detectable changes in subunit molecular weight. These findings may have implications for the definition of the molecular defect in hemophilic factor VIII. PMID- 4199415 TI - Immunology of the lower respiratory tract. Functional properties of bronchoalveolar lymphocytes obtained from the normal canine lung. AB - While the alveolar macrophage has been studied extensively, little attention has been directed toward the immune functions of the bronchoalveolar lymphocyte. These cells, obtained by bronchopulmonary lavage of the normal canine lung, are derived from the air side of the alveolar-capillary membrane of the lower respiratory tract. The distribution of lymphocyte types within the bronchoalveolar cell population was determined and compared with that of leukocytes from blood and spleen.IgG synthesis in vitro was used as a measure of bone marrow-derived lymphocyte (B cell) function, and the blastogenic response of cell cultures to phytohemagglutinin was used as a measure of the presence or absence of thymus-dependent lymphocytes (T cells). De novo synthesis of IgG by bronchoalveolar cells was demonstrated consistently by two independent radio immunoassays. Therefore, B cells are present in the air spaces of normal canine lungs. T cells were generally not detectable in aliquots of the same cell populations but could be recruited into alveolar spaces after local irritation. The distribution of lymphocyte types within the bronchoalveolar cell population is unique and distinctly different from that of blood and spleen. The spleen is rich in both T cells and B cells, blood is rich in T cells but poor in B cells, whereas the lung lacks T cells and contains substantial numbers of immunoglobulin producing B cells. The findings indicate that bronchoalveolar lymphocytes do not reflect simply the lymphoid composition of peripheral blood. PMID- 4199416 TI - Effective erythropoiesis induced by 5beta-pregnane-3beta-hydroxy-20-one in squirrel monkeys. AB - The erythropoietic effect of 5beta-pregnane-3beta-hydroxy-20-one, a naturally occurring steroid metabolite of progesterone, was evaluated in the squirrel monkey by ferrokinetic studies. red cell survival, and blood volume measurements. The intramuscular administration of this steroid in pharmacologic doses shortened the (59)Fe plasma clearance and increased the plasma iron turnover, thereby indicating an increase in erythropoiesis. A normal (59)Fe red cell uptake was observed, and the bone marrow maturation time was not altered. Red cell survival was the same in the treated and control groups. After five weekly injections of the steroid, the monkeys increased their red cell mass by 57%. A significant increase in white blood cells and a slight elevation of platelet counts in the treated monkeys also suggest a possible direct stimulation of hemopoietic stem cells by the steroid metabolite. These observations indicate that some steroid metabolites can stimulate an early increase in iron turnover (within 48 h) that is not secondary to hemolysis. The increased red cell mass indicates effective erythropoiesis in primates. PMID- 4199417 TI - Repetitive administration of thyrotropin-releasing hormone results in small elevations of serum thyroid hormones and in marked inhibition of thyrotropin response. AB - Repetitive administration of thyrotropin-releasing hormone (TRH) to human subjects was used to produce small elevations of endogenous serum triiodothyronine (T(3)) and thyroxine (T(4)) levels and thereby to determine the effect of these small elevations on the serum thyrotropin (TSH) response to subsequent doses of TRH. Each subject received 13 consecutive doses of 25 mug TRH at 4-h intervals. Serum T(3), T(4), and TSH levels were measured before the 1st, 7th, and 13th doses ("basal levels") and for the 4 h after each of these doses. In 10 normal subjects, the mean TSH response fell from 14.6 muU/ml after the 1st TRH dose to 6.9 and 3.0 muU/ml after the 7th, and 13th doses. These falls in TSH response were accompanied by rises in the mean basal serum T(3) levels from 81 to 115 to 114 ng/100 ml (normal range, 70-150 ng/100 ml) and rises in the mean basal serum T(4) from 6.7 to 8.6 to 9.5 mug/100 ml (normal range, 5-11 mug/100 ml). These data suggest that TRH-induced TSH release is extremely sensitive to inhibition by small elevations, not above the normal ranges, of serum T(3) and T(4) of endogenous origin. In four patients with primary hypothyroidism, the mean TSH responses were 92, 137, and 92 muU/ml after the 1st, 7th, and 13th TRH doses. The corresponding mean basal serum T(3) and T(4) levels at the times of these doses were 34, 30, and 32 ng/100 ml and 1.9, 1.9, and 1.7 mug/100 ml. These data show that repetitive administration of TRH does not result in progressively lower TSH responses in the absence of corresponding increases in serum T(3) and T(4) level. The progressive fall in TSH response observed in the normal subjects, therefore, was apparently due to the corresponding small increases in serum T(3) and T(4) levels and not to progressive depletion of pituitary TSH. In two patients with presumed TRH deficiency, the TSH responses were blunted by repetitive TRH doses but only when the serum T(3) and T(4) levels increased to within the normal ranges. TRH deficiency was thus confirmed for the first time by producing euthyroidism by replacement of TRH. PMID- 4199419 TI - [Biosynthesis and accumulation of dipicolinic acid in spore-forming bacteria. 2. Isolation of an active compound catalyzing the synthesis of dipicolinic acid from the diketopimelate-NH3 complex]. PMID- 4199420 TI - [Progress in hyperalimentation and alimentation via superior vena cava]. PMID- 4199418 TI - Thyroid hormone inhibition of the prolactin response to thyrotropin-releasing hormone. AB - The influence of serum triiodothyronine (T(3)) and thyroxine (T(4)) concentrations on the release of prolactin in man was studied by determining the prolactin response to synthetic thyrotropin-releasing hormone (TRH) in hypothyroid and hyperthyroid patients before and after correction of their serum thyroid hormone abnormalities. The maximum increment in serum prolactin above the basal level (maximum Delta prolactin) was used as the index of response to TRH. In 12 patients with primary hypothyroidism, the maximum Delta prolactin in response to TRH fell from 100.5+/-29.1 ng/ml (mean +/-SEM) before treatment to 36.1+/-6.0 ng/ml (P < 0.01) during the 4th wk of treatment with 30 mug T(3) + 120 mug T(4) daily. The mean serum T(3) level increased from 57+/-8 to 138+/-10 ng/100 ml, and the mean serum T(4) level increased from 3.0+/-0.4 to 7.2+/-0.4 mug/100 ml during this treatment. In eight normal subjects the maximum Deltaprolactin in response to TRH was not significantly different during the 4th wk of treatment with 30 mug T(3) + 120 mug T(4) daily from the response before treatment. In 10 patients with hyperthyroidism, the maximum Deltaprolactin in response to TRH increased from 14.2+/-2.9 ng/ml before treatment to 46.9+/-6.7 ng/ml (P < 0.001) during antithyroid treatment. The mean serum T(3) level fell from 313+/-47 to 90+/-8 ng/100 ml, and the mean serum T(4) level fell from 20.8+/ 2.5 to 6.8+/-0.6 mug/100 ml during this treatment. These results show that changes from normal serum levels of T(3) and T(4) are associated with changes in prolactin responses to TRH; subnormal serum levels of T(3) and T(4) increase TRH induced prolactin release, whereas substantially higher than normal serum levels of T(3) and T(4) inhibit this release. PMID- 4199421 TI - [Classification of infusion fluids and indications for their use]. PMID- 4199422 TI - [Mutant of Aspergillus flavus]. PMID- 4199423 TI - Stimulation of nonimmunized lymphocytes by platelet-antibody complexes in idiopathic thrombocytopenic purpura. PMID- 4199424 TI - [Risk of phosphorus depletion in prolonged parenteral feeding in infants]. PMID- 4199425 TI - [Manometric studies in patients with esophageal diverticula]. PMID- 4199426 TI - [Results of the use of iontophoresis in endodontics]. PMID- 4199427 TI - [Dental graft. Evaluation of our current knowledges]. PMID- 4199428 TI - [Calcification and ossification of periarticular soft tissues in thermal burns]. PMID- 4199429 TI - [Ossification in the upper extremities in spinal cord trauma]. PMID- 4199430 TI - [Intraspinal schwannosis of Lissauer's zone terminalis (formes frustes of Recklinghausen's neurofibromatosis or reactive?)]. PMID- 4199431 TI - Lysine supplementation of wheat gluten at adequate and restricted energy intakes in young men. PMID- 4199432 TI - Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. I. A functional defect in hepatic retinol release. PMID- 4199434 TI - Effects of chromium supplementation on growth in marasmic protein--calorie malnutrition. PMID- 4199433 TI - Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. II. Treatment including supplemental vitamin A. PMID- 4199435 TI - Endotoxin-induced protection against experimental Junin virus infection. PMID- 4199436 TI - Effect of eight fungicides on microbial activities in soil as measured by a bioassay method. PMID- 4199437 TI - Ultrastructural changes in the midgut epithelium of an elaterid larva (Coleoptera) infected enterically with Pseudomonas aeruginosa. PMID- 4199438 TI - Electron microscope and physical chemical characterization of C-phycocyanin from fresh extracts of two blue-green algae. PMID- 4199439 TI - Association of virulence characteristics of Erwinia amylovora with toxigenicity of its phage lysates to rabbit. PMID- 4199440 TI - [Functional elimination of diverticula of Vater's papilla by combined papilla diverticulum plastic surgery]. PMID- 4199441 TI - [Experiences with parenteral feeding and its utilization]. PMID- 4199442 TI - [Technic of long-term parenteral feeding with special reference to intensive care]. PMID- 4199443 TI - [Principles of parenteral feeding in the child]. PMID- 4199444 TI - [Parenteral feeding of the infant and premature infant]. PMID- 4199445 TI - [Indications for parenteral feeding using fat infusions in pediatric surgery]. PMID- 4199446 TI - [Significance of nutrition in the prognosis of apallic syndrome]. PMID- 4199447 TI - [Behavior of plasma lipid fractions during long-term parenteral feeding using fats in patients with servere craniocerebral injuries (CCI)]. PMID- 4199448 TI - [Treatment of burns at the Karolinska Hospital]. PMID- 4199449 TI - [Long-term parenteral feeding in severe tetanus]. PMID- 4199450 TI - [Significance of blood transfusion in parenteral feeding]. PMID- 4199451 TI - [Pulmonary tolerance of soy-bean-oil emulsions]. PMID- 4199452 TI - [Surface activity measurements on the rabbit lung following infusion of fat emulsions]. PMID- 4199453 TI - [Pathological and anatomical findings in hyperlipemias]. PMID- 4199454 TI - [Review on the balance of energy substances with special reference to the metabolism of glucose, fructose, sorbitol and xylitol and their therapeutic utilization]. PMID- 4199455 TI - [Nutrition physiological and pharmacological viewpoints on complete parenteral feeding]. PMID- 4199456 TI - Nutritional status of patients after extended tube feeding. PMID- 4199457 TI - Responses of the bovine lymphatic system to infection by Theileria parva. I. Histology and ultrastructure of lymph nodes in experimentally-infected calves. PMID- 4199458 TI - Responses of the bovine lymphatic system to infection by Theileria parva. II. Changes in the central lymph in experimentally-infected calves. PMID- 4199459 TI - Immunization against Brucella infections. Priming of Cynomolgus philipinensis with purified antigen of Brucella melitensis prior to injection of Rev. I vaccine. PMID- 4199460 TI - A colorimetric method for measurement of the (peroxidase-mediated) oxidation of 3,3'-diaminobenzidine. PMID- 4199461 TI - Inability of murine melanoma "tyrosinase" (dopa ozidase) to oxidize tyrosine in the presence or absence of dopa or dihydroxyfumarate cofactor. PMID- 4199462 TI - Fixation effects on the fine structure of enamel crystal-matrix relationships. PMID- 4199463 TI - Preliminary study of B. subtilis alpha-amylase crystals by electron microscopy and optical diffraction. PMID- 4199464 TI - Microcirculation and metabolism in the vascular wall concerned with the vasa vasorum. PMID- 4199465 TI - Absence of cross-reactive antigen in Fabry's disease. PMID- 4199466 TI - Anticonvulsants and fetal damage. PMID- 4199468 TI - [Restoration of pulpless teeth (case report)]. PMID- 4199469 TI - [Physical factors in retention of complete dentures]. PMID- 4199467 TI - [Food impaction as etiological factor in periodontal diseases]. PMID- 4199470 TI - [Orthodontic management of certain prosthodontic problems]. PMID- 4199471 TI - [Corrective operation of laterognathism]. PMID- 4199472 TI - Wilson's disease in the United Kingdom and Taiwan. I. General characteristics of 142 cases and prognosis. II. A genetic analysis of 88 cases. PMID- 4199473 TI - [The hemopulpogram after treatment with Ledermix]. PMID- 4199474 TI - Comparison of acute oral toxicity of cannabinoids in rats, dogs and monkeys. PMID- 4199475 TI - Fish bile analysis: a possible aid in monitoring water quality. PMID- 4199476 TI - Ocular manifestations of dwarfism. PMID- 4199477 TI - [Engram as an equivalent of releasing afferentation]. PMID- 4199479 TI - [Histological follow-up studies on drug induced liver necroses]. PMID- 4199478 TI - [Morphophysiological prerequisites for the systemic organization of the brain]. PMID- 4199480 TI - [Alpha 1 antitrypsin in rheumatic diseases]. PMID- 4199481 TI - Extraction of carboxylic acids as adducts with dibenzo-18-crown-6. PMID- 4199482 TI - Intraarterial administration of emulsion formulations containing cyclandelate and nitroglycerin. PMID- 4199483 TI - Preparation of protein-steroid conjugates and antisera against oestradiol-17 . PMID- 4199484 TI - Micrococcus indolicus. Some biochemical properties, and the demonstration of sex antigenically different types. PMID- 4199485 TI - Levels of polychlorinated biphenyls (PCB) and organochlorine insecticides in eggs from eider (Somateria mollissima). PMID- 4199486 TI - Clinical aspects of Rh immunization. Philip Levine Award Address. PMID- 4199487 TI - [Peculiar mode of division in Ichthyophthirius multifiliis]. PMID- 4199488 TI - Long-term continuous exposure to sulfur dioxide and fly ash mixtures in cynomolgus monkeys and guinea pigs. PMID- 4199489 TI - An investigation into the mode of transmission of sarcosporidiosis. PMID- 4199490 TI - The effect of a combined preparation of trimethoprim and sulphamethoxazole following short-term and long-term administration on the flora of the human gut. PMID- 4199491 TI - Factors in the pathogenesis of experimental nonketotic and ketoacidotic diabetic stupor. PMID- 4199492 TI - [Prostaglandins: somatic substances and possible remedies]. PMID- 4199493 TI - Effects of cations and colchicine on the release of prolactin and growth hormone by functional pituitary tumor cells in culture. PMID- 4199494 TI - Levels of serum LH in rhesus monkeys after intrapituitary infusion of synthetic LH-RH or median eminence extracts. PMID- 4199495 TI - Effect of immunization with estrone-protein conjugate in rhesus monkeys. PMID- 4199496 TI - The influence of lactation on luteal function in the rhesus monkey. PMID- 4199497 TI - The metabolism of saccharin in laboratory animals. PMID- 4199498 TI - Polychlorinated biphenyls: evidence of transplacental passage in the Sherman rat. PMID- 4199499 TI - [Factors facilitating heteromorphism and competence in the genetic transformation of Bacillus subtilis]. PMID- 4199500 TI - Normal development of the jaws and teeth in pigs, and the delay and malocclusion produced by calorie deficiencies. PMID- 4199501 TI - The innervation of the cerebral arteries. PMID- 4199502 TI - Pleiotropic menaquinone-deficient mutant of Bacillus subtilis. AB - A multiple aromatic amino acid auxotroph of Bacillus subtilis 168 has been isolated which is unable to synthesize menaquinone-7 (MK-7) unless supplied with shikimic acid (SHK). The mutant, RB163, was isolated by selecting for resistance to low levels (1.5 mug/ml) of kanamycin. Enzymatic and genetic analyses show that the strain is an aroD mutant lacking 5-dehydroshikimate reductase. Under growth conditions in which its MK-7 deficiency is expressed, RB163 is deficient in cytochromes a, b, and c, exhibits low growth yields, and does not sporulate. Genetic analysis indicates that this pleiotropic phenotype is the result of a single genetic event. All phenotypic characteristics are reversible when the mutant is grown under conditions such that MK is synthesized. Comparison of strain RB163 with other aro mutants blocked before SHK ("early-aro" mutants) reveals interesting differences. Most early-aro mutants are cytochrome- and MK sufficient, sporogenous, and sensitive to kanamycin when grown in the absence of SHK. However, in addition to strain RB163, two other aro mutants were found to show the pleiotropic phenotype. These three mutants have in common, and differ from other early-aro strains in, the inability to synthesize MK. It is suggested that the phenotypically wild-type aro mutants are bradytrophic, allowing enough substrate flow through the common aromatic pathway to satisfy the MK requirement. The pleiotropic mutants are thought to be completely blocked in the common pathway, thus accounting for their inability to synthesize MK. PMID- 4199504 TI - Phenotypes of pleiotropic-negative sporulation mutants of Bacillus subtilis. AB - The phenotypic properties of representatives of the five genetic classes of pleiotropic-negative sporulation mutants have been investigated. Protease production, alkaline and neutral proteases, was curtailed in spoA mutants, but the remainder of mutant classes produced both proteases, albeit at reduced levels. The spoA and spoB mutants plaqued phi2 and phi15 at high efficiency, but the efficiency of plating of these phages on spoE, spoF, and spoH mutants was drastically reduced. Antibiotic was produced by the spoH mutants and to a degree by some spoF mutants, but the other classes did not produce detectable activity. The spoA mutants were less responsive to catabolite repression of histidase synthesis by glucose than was the wild type. Severe catabolite repression could be induced in spoA mutants by amino acid limitation, suggesting that the relaxation of catabolite repression observed is not due to a defect in the mechanism of catabolite repression. Although others have shown a perturbation in cytochrome regulation in spoA and spoB mutants, the primary dehydrogenases, succinate dehydrogenase and reduced nicotinamide adenine dinucleotide dehydrogenase, leading to these cytochromes are unimpaired in all mutant classes. A comparison of the structural components of cell walls and membranes of spoA and the wild type is made. The pleiotropic phenotypes of these mutants are discussed. PMID- 4199503 TI - Penicillinases of Klebsiella pneumoniae and their phylogenetic relationship to penicillinases mediated by R factors. AB - On the assumption that the penicillinase determinants on a group of R factors conferring ampicillin resistance have a phylogenetically close relationship to the penicillinase gene of the Klebsiella group, the penicillinases from four strains of K. pneumoniae, GN69, GN1103R(-), GN422, and GN118, were purified 230- to 1,000-fold and compared with the known two R-factor-mediated penicillinases. By gel filtration on Sephadex G-75, the molecular weights were estimated to be 17,400, 18,100, 20,000 and 18,300, respectively, which are slightly lower than those of the R-factor penicillinases. The isoelectric points of the Klebsiella penicillinases were not in agreement with those of the R-factor penicillinases. All the enzymes showed a pH optimum between 6.3 to 7.2 and a temperature optimum of 45 C, and those properties, together with behavior towards inhibitors, were about the same as those in the R-factor penicillinases. The substrate specificity and the Michaelis constants of the Klebsiella penicillinases for penicillins and cephaloridine were broadly similar to those of the R-factor penicillinases, however, some variations were found even among the four penicillinases of K. pneumoniae. The reactivities of the four penicillinases of K. pneumoniae with the antiserum against one R-factor penicillinase were tested, and three of the four Klebsiella penicillinases were found to be indistinguishable immunologically from both R-factor penicillinases. The remaining Klebsiella penicillinase, from GN1103R(-), showed an immunological partial homology with the R-factor penicillinases. PMID- 4199506 TI - Deoxyribonucleic acid-deoxyribonucleic acid hybridization of R factors. AB - A new method of estimating deoxyribonucleic acid homology is presented and used to measure the homology between bacterial plasmids of different compatibility groups. Deoxyribonucleic acid of the P-group plasmid RP1, originally isolated in Pseudomonas aeruginosa, has considerable (50%) homology with an N-group plasmid of the Enterobacteriaceae. PMID- 4199505 TI - Ethidium bromide-resistant mutant of Bacillus subtilis. AB - An ethidium bromide-resistant mutant (EB8) derived from a Marburg strain of Bacillus subtilis was found to be conditionally resistant to 10 mug of ethidium bromide per ml. Expression of resistance is complete only during vegetative growth at incubation temperatures above 30 C in complex medium or minimal medium supplemented with Casamino Acids. Strain EB8 is cross-resistant to acriflavine and proflavine. The ethidium bromide resistance marker is co-transduced with hisA1 at a frequency of 6% and is located to the right of hisA1 on the B. subtilis chromosome as it is usually represented on the map. Incorporation of [5 (3)H] uridine by strain EB8 showed that ribonucleic acid synthesis in both whole cells and protoplasts is ethidium bromide-resistant. PMID- 4199507 TI - Release and recovery of forespores from Bacillus cereus. AB - A method is described which makes possible the release of immature forespores from sporulating cells at specific stages of development, from the completion of stage III through to mature spore formation. With the aid of zonal density gradient centrifugation, the method makes possible the recovery of quantities of forespores ample for biochemical and physical studies. With the capability to examine forespores and some mother cell components independently, we have established that several enzymes associated with the sporulation process are localized in the newly developed forespores. Studies showed that aspartate aminotransferase and alanine aminotransferase are associated with the forespores, whereas l-alanine dehydrogenase is found only in the mother cell cytoplasm. PMID- 4199508 TI - Exosporium and spore coat formation in Bacillus cereus T. AB - The exosporium of Bacillus cereus T was first observed as a small lamella in the cytoplasm in proximity to the outer forespore membrane (OFSM) near the middle of the sporangium. Serial sections, various staining methods, and enzyme treatments failed to show any connections between the small lamella and the OFSM. The advancing edge of the exosporium moved toward the polar end of the cell until the spore was completely enveloped. The middle coat was formed between the exosporium and the OFSM from a three-layered single plate or "belt," consisting of two electron-dense layers separated by an electron-transparent layer. This "belt," usually first observed toward the center of the sporangium, developed without changing thickness or appearance over the surface of the forespore. Between the middle coat and the OFSM, a layer of cytoplasm about 50-nm thick was enclosed by the developing coat; this became the inner coat. Electron-dense material was deposited on the outer surface of the middle coat to form the outer coat. PMID- 4199509 TI - Rapid method for isolation of large quantities of outer membrane from Escherichia coli K-12 and its application to the study of envelope mutants. AB - A rapid method for the isolation of large quantities of bacterial outer membrane is described. This cell envelope component was removed from plasmolyzed cells of Escherichia coli K-12 by lysozyme-ethylenediaminetetra-acetic acid treatment, aggregated by lowering the pH to 5.0, and recovered by centrifugation. Aggregates of membrane fragments were clearly identified in an electron microscope. A criterion of homogeneity of the preparation was obtained by isopycnic sucrose gradient centrifugation. A single band appeared at a density of 1.24 g/cc. The cytoplasmic membrane marker, succinate dehydrogenase activity, was 40 times lower in the outer membrane preparation than in complete cell envelope preparations. A rich activity was, however, found for the outer membrane marker, phospholipase A. The compositions of outer membranes from a transductant pair were compared. One transductant was a chain-forming, antibiotic-supersensitive envA strain, whereas the other contained the envA(+) allele. The envA strain showed a slightly modified protein pattern and a lower relative content of phosphatidylglycerol. PMID- 4199510 TI - Genetic mapping of a mutant defective in D,L-alanine racemase in Bacillus subtilis 168. AB - Genetic analysis of a d-alanine requiring mutant (dal) of Bacillus subtilis reveals that the gene that codes for d,l-alanine racemase is linked to purB. The order of genes in this region of the chromosome is purB, pig, tsi, dal. Thus there are at least two clusters of genes that regulate cell wall biosynthesis in B. subtilis. PMID- 4199511 TI - Effect of biogenic amines and cannabinoids on bacterial chemotaxis. AB - The chemotactic response of Pseudomonas fluorescens was significantly enhanced by the stimulants dl-amphetamine and epinephrine. Acetylcholine, a physiological antagonist of epinephrine, and the cannabinoid tetrahydrocannabinol inhibited bacterial chemotaxis. It may be possible to use bacterial chemotaxis as a bioassay in biochemical studies of drug action. PMID- 4199513 TI - Threonine synthetase-catalyzed conversion of phosphohomoserine to alpha ketobutyrate in Bacillus subtilis. AB - An enzyme activity of Bacillus subtilis has been found that catalyzes the dephosphorylation and deamination of phosphohomoserine to alpha-ketobutyrate, resulting in a bypass of threonine in isoleucine biosynthesis. In crude extracts of a strain deficient in the biosynthetic isoleucine-inhibitable threonine dehydratase, phosphohomoserine was converted to alpha-ketobutyrate. Phosphohomoserine conversion to alpha-ketobutyrate was shown not to involve a threonine intermediate. Single mutational events affecting threonine synthetase also affected the phosphohomoserine-deaminating activity, suggesting that the deamination of phosphohomoserine was catalyzed by the threonine synthetase enzyme. It was demonstrated in vivo, in a strain deficient in the biosynthetic threonine dehydratase, that isoleucine was synthesized from homoserine without intermediate formation of threonine. PMID- 4199512 TI - Genetic and biochemical characterization of mutants of Bacillus subtilis defective in succinate dehydrogenase. AB - Eleven succinate-accumulating mutants of Bacillus subtilis have been mapped by transformation and transduction crosses and characterized with respect to activities of citric acid cycle enzymes. These mutants could be divided into three genetic groups. Nine of the mutants were found to map between argA and leu in the citF locus. A second group was located between lys-1 and trpC2 and the third group could not be located on the B. subtilis chromosome in extensive transduction crosses. All of the citF mutants lack detectable succinate dehydrogenase activity, whereas both of the other groups show a reduced level of this enzyme. In addition, most of the mutants in the citF locus lack cytochrome a, whereas the level of this cytochrome is normal in the other two groups. A procedure has been devised for the solubilization of the succinate dehydrogenase from the membrane of B. subtilis with the non-ionic detergent Brij 58. Some properties of the soluble and bound forms of succinate dehydrogenase are described. PMID- 4199514 TI - Transduction of lactose metabolism in Streptococcus lactis C2. AB - Ultraviolet (UV)-induced phage lysates, from lactose-positive (lac(+)) Streptococcus lactis C2, transduced lactose fermenting ability to lac(-) recipient cells of this organism. Although the phage titer could not be determined due to the absence of an appropriate indicator strain, the number of transductants was proportional to the amount of phage lysate added. Treatment of the lysate with deoxyribonuclease had no effect on this conversion, indicating the observed genetic change was not mediated by free deoxyribonucleic acid. When the lac(+) transductants were isolated and exposed to UV irradiation, lysates with higher transducing ability were obtained. The transducing ability of this lysate was about 100-fold higher than that observed in the original lysates. The lac(+) transductants were unstable since lac(-) segregants occurred at high frequency. The phage lysate from S. lactis C2 also transduced maltose and mannose metabolism to the respective negative recipient cells. The results demonstrate the transduction of carbohydrate markers by a streptococcal phage and establish a genetic transfer system in group N streptococci. PMID- 4199515 TI - Lipopolysaccharide layer protection of gram-negative bacteria against inhibition by long-chain fatty acids. AB - Growth, amino acid transport, and oxygen consumption of Escherichia coli and Salmonella typhimurium are inhibited by short-chain (C(2)-C(6)) but not by medium or long-chain fatty acids (C(10)-C(18)) at concentrations at which these processes are completely inhibited in Bacillus subtilis. The resistance of gram negative organisms is not correlated with their ability to metabolize fatty acids, since an E. coli mutant unable to transport oleic acid is still resistant. However, mutants of both E. coli and S. typhimurium in which the lipopolysaccharide layer does not contain the residues beyond the 2-keto-3 deoxyoctonate core are inhibited by medium (C(10)) but not by long-chain (C(18)) fatty acids. Furthermore, removal of a portion of the lipopolysaccharide layer by ethylenediaminetetraacetate treatment renders the organisms sensitive to medium and partially sensitive to long-chain fatty acids. The intact lipopolysaccharide layer of gram-negative organisms apparently screens the cells against medium and long-chain fatty acids and prevents their accumulation on the inner cell membrane (site of amino acid transport) at inhibitory concentrations. These results are relevant to the use of antimicrobial food additives, and they allow the characterization of gram-positive versus gram-negative bacteria and their lipopolysaccharide mutants. PMID- 4199516 TI - Hydroxamate recognition during iron transport from hydroxamate-ion chelates. AB - Kinetics of radioactive iron transport from three structurally different secondary hydroxamate-iron chelates (schizokinen-iron, produced by Bacillus megaterium ATCC 19213; Desferal-iron, produced by an actinomycete; and aerobactin iron, produced by Aerobacter aerogenes 62-1) revealed that B. megaterium SK11 (a mutant which cannot synthesize schizokinen) has a specific transport system for utilization of ferric hydroxamates with a recognition capacity based on the chemical structure of the hydroxamate. Both Desferal and schizokinen enhanced iron uptake in this organism; however, Desferal-iron delivered only one-sixth the level of iron incorporated from the schizokinen-iron chelate. Desferal-iron did not generate the rapid rates of iron transport noted with schizokinen-iron at elevated iron concentrations. Assays containing large excesses of either iron free Desferal or iron-free schizokinen suggested that the iron-free hydroxamate may compete with the ferric hydroxamate for acceptance by the transport system although the system has greater affinity for the iron chelate. Aerobactin-iron did not stimulate iron uptake in B. megaterium SK11 and aerobactin inhibited growth of this organism, indicating that B. megaterium SK11 cannot efficiently process the aerobactin-iron chelate. PMID- 4199517 TI - Fate of labeled hydroxamates during iron transport from hydroxamate-ion chelates. AB - The fate of the hydroxamic acid-iron transport cofactors during iron uptake from the (59)Fe(3+) chelates of the (3)H-labeled hydroxamates schizokinen and aerobactin was studied by assay of simultaneous incorporation of both (59)Fe(3+) and (3)H. In the schizokinen-producing organism Bacillus megaterium ATCC 19213 transport of (59)Fe(3+) from the (3)H-schizokinen-(59)Fe(3+) chelate at 37 C was accompanied by rapid uptake and release (within 2 min) of (3)H-schizokinen, although (3)H-schizokinen discharge was temperature-dependent and did not occur at 0 C. In the schizokinen-requiring strain B. megaterium SK11 similar release of (3)H-schizokinen occurred only at elevated concentrations of the double-labeled chelate; at lower chelate concentrations, (3)H-schizokinen remained cell associated. Temperature-dependent uptake of deferri (iron-free) (3)H-schizokinen to levels equivalent to those incorporated from the chelate form was noted in strain SK11, but strain ATCC 19213 showed only temperature-independent binding of low concentrations of deferri (3)H-schizokinen. These results indicate an initial temperature-independent binding of the ferric hydroxamate which is followed rapidly by temperature-dependent transport of the chelate into the cell and an enzyme catalyzed separation of iron from the chelate. The resulting deferri hydroxamate is discharged from the cell only when a characteristic intracellular concentration of the hydroxamate is exceeded, which happens in the schizokinen requiring strain only at elevated concentrations of the chelate. This strain also appears to draw the deferri hydroxamate into the cell by a temperature-dependent mechanism. The aerobactin-producing organism Aerobacter aerogenes 62-1 also demonstrated rapid initial uptake and temperature-dependent discharge of (3)H aerobactin during iron transport from (3)H-aerobactin-(59)Fe(3+), suggesting a similar ferric hydroxamate transport system in this organism. PMID- 4199518 TI - Efficiency of energy conversion by aerobic glucose metabolism in Aphancapsa 6714. AB - Efficiency of adenosine triphosphate (ATP) formation from glucose oxidation in Aphanocapsa 6714 was estimated by quantitative measurement of phosphorylated intermediary metabolites and glycogen (polyglucose) formed from (14)C-glucose. P/2e ratios based on oxygen uptake ranged from 2.62 to 3.08, whereas those based on (14)CO(2) evolution ranged from 1.66 to 1.72. The synthesis of glycogen, which is the dominant energy-consuming process in resting cells exposed to exogenous glucose, was almost totally inhibited under anaerobic conditions, and the cellular concentration of ATP decreased steadily. Thus, both net synthesis of ATP and the steady-state concentration of ATP are obligatorily linked to respiration in this heterotrophic unicellular blue-green alga. PMID- 4199519 TI - Kinetics of glucose incorporation by Aphanocapsa 6714. AB - Photoautotrophic metabolism of CO(2) was compared with glucose metabolism in the facultative unicellular blue-green alga, Aphanocapsa 6714. Glucose-fed cells incorporated more (14)C into phosphorylated sugar intermediates of the reductive and oxidative pentose phosphate cycles than autotrophic cells. The relative increases were: 140-fold in dark cells; 32-fold in dichlorophenylmethylurea (DCMU)-inhibited cells; and 16-fold in cells assumilating glucose during photosynthetic carbon reduction. On the other hand, incorporation of (14)C from glucose into 3-phosphoglycerate and the amino acid pools of glutamate and aspartate was reduced in dark cells. Rates of protein synthesis in dark and DCMU inhibited cells were reduced 50 and 80% compared to photoautotrophic cells. In cells assimilating glucose during photosynthesis, rates of (14)C incorporation into the two amino acids and protein were the same as in photoautotrophic cells. Chase experiments, using an excess of (12)C-glucose and CO(2), revealed slow turnover of carbon in dark cells and intermediate turnover rates in DCMU inhibited cells, when compared to cells assimilating glucose during photosynthesis. PMID- 4199520 TI - Cell-bound thiaminase I of Bacillus thiaminolyticus. AB - The distribution of the extracellular enzyme, thiaminase I, was determined for logarithmically growing cultures of Bacillus thiaminolyticus. About 60% of the enzyme is associated with the cells throughout the growth cycle. The remainder of the enzyme is in the culture medium. The release of the cell-bound thiaminase I is examined under a variety of conditions. The rate and extent of release is dependent on the pH and the nature of the incubation solution. The release process appears to be relatively independent of de novo protein synthesis, energy derived from oxidative phosphorylation, or divalent metal ions. The absence of carbon or nitrogen sources has little effect on the release of the enzyme. Cell bound thiaminase I probably is the immediate precursor for extracellular thiaminase I found in the culture medium. Washed cells continue to release thiaminase I at the expense of cell-bound enzyme. In addition, purified cell bound thiaminase I is indistinguishable from purified extracellular thiaminase I by a number of physical and kinetic criteria. PMID- 4199521 TI - Reversible inactivation of thiaminase I of Bacillus thiaminolyticus by its primary substrate, thiamine. AB - Thiaminase I of Bacillus thiaminolyticus is reversibly inactivated when it is incubated with its primary substrate, thiamine, or with one of several structural analogues of thiamine in the absence of an acceptor base. The inactivation reaction is pH and temperature dependent and is stochiometric with respect to thiamine and thiaminase I concentrations. One molecule of thiamine is cleaved for each molecule of enzyme inactivated. Inactivation is prevented or reversed by sulfhydryl-reducing agents. Active or reactivated thiaminase I migrate as a single band in polyacrylamide electrophoresis gels. Inactive thiaminase I appears to migrate as two separate bands. Active, inactive, and reactivated thiaminase I are immunologically similar. A possible mechanism for the inactivation of thiaminase I by its substrate is discussed. PMID- 4199522 TI - Comprehensive rehabilitation of the patient with cancer. Five-year experience of a home-care unit. PMID- 4199523 TI - Precipitating antibody against pigeon antigens in sera of asymptomatic pigeon breeders. PMID- 4199524 TI - Characterization and significance of urinary fibrin degradation products. PMID- 4199525 TI - Hepatic drug metabolism and protein malnutrition. PMID- 4199526 TI - Prolonged survival after complete small bowel resection using intravenous alimentation at home. PMID- 4199527 TI - Sensitivity testing with trimethorpim-sulphamethoxazole. PMID- 4199528 TI - Co-trimaxazole therapy: place and prospects. PMID- 4199530 TI - Trimethoprim-sulphamethoxazole: long-term therapy and folate levels. PMID- 4199529 TI - Trimethoprim-sulphamethoxazole effect on folate metabolism. PMID- 4199531 TI - [Seroprotective test in the chick embryo. Possibilities of application and study of antityphoid-paratyphoid immunity]. PMID- 4199532 TI - [Quantitative determination of C-reactive protein by simple radial immunodiffusion]. PMID- 4199533 TI - Inhibition by imidazole of the increase in intraocular pressure induced by topical prostaglandin E. PMID- 4199534 TI - [Residues of DDT and PCB in Norwegian sprat (Clupea sprattus) and herring (Clupea harengus)]. PMID- 4199535 TI - [Peracute mastitis caused by Bacillus cereus]. PMID- 4199536 TI - [The bacteriology of dehydrated vegetable products]. PMID- 4199537 TI - [Orthopedic aid to children with deformities of the talocrural joint following traumatic osteoepiphysiolysis]. PMID- 4199538 TI - Serum growth hormone in diabetic coma. PMID- 4199539 TI - Failure of SC-19220 to affect prostaglandin E1 (PGR1) gastric antisecretory actions. PMID- 4199540 TI - [Study of the possibility of modifying radiation damage to mammalian cells by bacterial DNA ligase]. PMID- 4199541 TI - [Technical peculiarities and application possibilities of a linear accelerator]. PMID- 4199542 TI - Thio-TEPA therapy to prevent postoperative pterygium occurrence and neovascularization. PMID- 4199543 TI - Pressure-dependency of the aqueous outflow. PMID- 4199544 TI - [Ethylenimines of phosphoric acids as chemosterilants]. PMID- 4199545 TI - Angiologic assessment of the hemodynamic effects of sustained release nitroglycerin in patients with angina pectoris. PMID- 4199546 TI - [Hepatozoon mauritanicum (Et. and Ed. Sergent, 1904) n. comb., a parasite of Testude graeca: a new description of sporogony in Hyalomma aegyptium and of tissular schizogony drawn from the material of E. Brumpt]. PMID- 4199548 TI - [Observations on Nephridiophaga forficulae (Leger, 1909), a parasite of the Malphighian tubules of Forficula auricularia L]. PMID- 4199547 TI - [Nonspecific precipitation reaction with an antigen of Sarcocystis tenella]. PMID- 4199549 TI - Care of anesthetic equipment and other devices. PMID- 4199550 TI - The isolation of erythrocyte membrane proteins in aqueous media. PMID- 4199551 TI - [Roentgen morphological and functional pyloric changes following vagotomy and drainage surgery]. PMID- 4199552 TI - Interaction of thyroxine with rat adenohypophysial proteins in vitro. PMID- 4199553 TI - Elimination of recessive lethals in model populations of Drosophila melanogaster. PMID- 4199554 TI - Infectious DNA from coliphage T1. IV. The action of radicals induced by 60Co gamma rays in the wet state. PMID- 4199555 TI - Lymphocyte phytohemagglutinin responsiveness, immunoglobulins and autoantibodies in aging humans. PMID- 4199556 TI - Synthesis of IgG, IgA, IgM by chicken tissues: immunofluorescent and 14C amino acid incorporation studies. PMID- 4199557 TI - Immunoglobulins in the developing amphibian, Rana catesbeiana. PMID- 4199558 TI - Human immunoglobulin A: production of an Fc fragment by an enteric microbial proteolytic enzyme. PMID- 4199559 TI - The role of thymus-derived lymphocytes in the in vitro activation of macrophages to kill Listeria monocytogenes. PMID- 4199560 TI - Antinucleolar antibodies in human sera. PMID- 4199561 TI - Changing patterns of bacterial meningitis in Olmsted County, Minnesota, 1935 1970. PMID- 4199563 TI - Rocky Mountain spotted fever: a comparative study of the active immunity induced by inactivated and viable pathogenic Rickettsia rickettsii. PMID- 4199562 TI - Preliminary characterization of the heat-labile enterotoxin of Escherichia coli F11(P155). PMID- 4199564 TI - Electron microscope study of the structures of the Bacillus subtilis prophages, SPO2 and phi105. PMID- 4199565 TI - Electron microscope mapping of the distribution of ribosomal genes of the Bacillus subtilis chromosome. PMID- 4199566 TI - Scintillation cameras and multiprobe detectors--their advantages and disadvantages in brain perfusion measurements. PMID- 4199567 TI - An electromechanical hypothesis for ciliary coordination in ciliated protozoa. PMID- 4199568 TI - [PCB poisoning--pathological findings of so-called "yusho" patients]. PMID- 4199569 TI - [Ocular manifestation in Cockayne's syndrome]. PMID- 4199570 TI - Immunological studies of factor VIII in haemophilia and von Willebrand's disease. PMID- 4199571 TI - Vitellogenesis induced by juvenile hormone in the female sterile mutant apterous four in Drosophila melanogaster. PMID- 4199572 TI - Microbiological quality of Norwegian butter and margarine. PMID- 4199573 TI - [Studies on the activity of proteolytic enzymes in Bacillus anthracis and Bacillus cereus]. PMID- 4199574 TI - Chronic thyroiditis in buffalo-strain rats ingesting 3'-methyl-4 dimethylaminoazobenzene or N-2-fluorenyldiacetamide. PMID- 4199575 TI - Prophylaxis of Rh-immunization with immunoglobulin anti-D. PMID- 4199576 TI - Purines and purine nucleoside antagonists. PMID- 4199577 TI - Enzymes as immunosuppressants: basic considerations. PMID- 4199578 TI - Diagnosis and management of infections associated with immunosuppression. New antibiotics of potential importance for immunosuppressed patients. PMID- 4199579 TI - Patient isolation units for cancer patients treated with chemical immunosuppressive agents. PMID- 4199580 TI - The in vivo activity of in vitro immunized mouse thymocytes. 3. Fate of in vitro immunized thymocytes. PMID- 4199581 TI - 51Cr release microassays for histocompatibility antigens on normal and malignant cells. PMID- 4199582 TI - Immunochemical specificity of cytoplasmic inclusions induced by viruses in the potato Y group. PMID- 4199583 TI - [Cytological studies on trichocysts. 8. Fine structure and function of toxicysts in Loxophyllum meleagris and Prorodon teres]. PMID- 4199584 TI - Testosterone regulation of pigmentation in scrotal epidermis of the rat. PMID- 4199585 TI - Serological cross-reactions between different Brucella species and Yersinia enterocolitica. Biological and chemical investigations of lipopolysaccharides from Brucella abortus and Yersinia enterocolitica type IX. PMID- 4199586 TI - Cell division after inhibition of DNA and protein synthesis in Neisseria meningitidis. 1. Blockage of division in synchronized populations by hydroxyurea and chloramphenicol. PMID- 4199587 TI - Cell division after inhibition of DNA and protein synthesis in Neisseria meningitidis. 2. Residual division and increase in absorbancy in exponential phase cultures after addition of hydroxyurea and chloramphenicol. PMID- 4199588 TI - The occurrence of measles antigen precipitating antibodies in sera from patients with multiple sclerosis and their relatives. PMID- 4199589 TI - Three new Escherichia coli O antigens O154, O155 and O156, and one new K antigen, K94. PMID- 4199590 TI - Epidemiological markers for Pseudomonas aeruginosa. 1. Serogrouping, pyocine typing--and their interrelations. PMID- 4199591 TI - Epidemiological markers for Pseudomonas aeruginosa. 2. Relationship between bacteriophage susceptibility and serogroup or pyocine type. PMID- 4199592 TI - Epidemiological markers for Pseudomonas aeruginosa. 3. Comparison of bacteriophage typing, serogrouping, and pyocine typing on a heterogeneous clinical material. PMID- 4199593 TI - Incidence of Rh immunization following abortion: possible detection of lymphocyte priming to Rh antigen. PMID- 4199594 TI - Community mental health services in Britain. PMID- 4199595 TI - Growth of bacteria and fungi in total parenteral nutrition solutions. PMID- 4199596 TI - [Treatment of resistant gonococcic urethritis]. PMID- 4199597 TI - [Use of the antigen Plasmodium berghei for the serodiagnosis of human malaria using indirect immunofluorescence]. PMID- 4199598 TI - [Thyroid cancer of the amyloid stroma. 1st observation in French-speaking Africa (Chad)]. PMID- 4199599 TI - Antitumor activities of bacterial leucine dehydrogenase and glutaminase A. PMID- 4199600 TI - The use of reporter group circular dichroism in the study of conformational transitions in bovine serum albumin. PMID- 4199601 TI - Use of elemental diet during the adaptive stage of short gut syndrome. PMID- 4199602 TI - Amino acid adequacy of parenteral casein hydrolysate and oral cottage cheese in patients with gastrointestinal disease as measured by nitrogen balance and blood aminogram. PMID- 4199603 TI - The problem-oriented medical record in long-term institutional care. PMID- 4199604 TI - Immunological studies of coagulation factor XIII. AB - Human fibrin-stabilizing factor (Factor XIII) has been studied immunologically by the preparation of specific anti-Factor XIII antiserum in rabbits. On immunodiffusion it was found that normal plasma produced two precipitin lines. One of the precipitin lines was identical with that present in soluble platelet extract (the alpha-component), the other with that present in normal serum (beta component). Plasma and serum of patients with congenital Factor XIII deficiency contained only the beta-component. By adsorption it was possible to prepare a second antiserum with solely anti-alpha-activity that did not react with the serum or plasma of XIII-deficient patients. Both antisera neutralized the clot stabilizing activity of normal plasma. The action of thrombin on fibrinogen-free plasma or platelet extract abolished the immunoprecipitin alpha-line but did not reduce the capacity to neutralize antibody as measured by clot stabilization. It is concluded that the plasma Factor XIII molecule consists of two immunologically identifiable components, alpha and beta. The clot-stabilizing activity and thrombin-reactive site are situated on the alpha-component. Patients with congenital Factor XIII deficiency are devoid of immunologically identifiable or functional alpha-component but retain immunologically identifiable beta component. It is this beta-component that accounts for the observed immunologically detectable Factor XIII in those patients devoid of clot stabilizing activity. PMID- 4199605 TI - Acute changes in oxyhemoglobin affinity. Effects on oxygen transport and utilization. AB - It has been postulated that 2,3-diphosphoglycerate (DPG)-mediated changes in oxyhemoglobin affinity play an important role in oxygen delivery; however, the effect of an acute increase in affinity without changing red cell mass has not been systematically evaluated. This study was designed to measure changes in oxygen transport and oxygen consumption produced by an acute increase in oxyhemoglobin affinity caused by an autologous exchange transfusion using DPG depleted stored blood. From each of 10 5-kg rhesus monkeys, 100 ml of blood was taken on the 1st and 3rd wk of the study and each stored in 25 ml of acid-citrate dextrose storage solution. On the 5th wk, each animal underwent an exchange transfusion with 200 ml of its stored blood. Hemodynamic data were obtained before and 30 min after transfusion. The oxyhemoglobin dissociation curve shifted to the left (P(50) changed from 33.9 to 27.2 mm Hg), as mean red cell DPG decreased from 28.6 to 12.7 mumol/g of hemoglobin. No significant change was noted in pH, P(CO2), base deficit, arterial or venous percent saturation of hemoglobin, cardiac output, or oxygen consumption. However, a fall in mixed venous P(O2) from 35.3 to 27.9 mm Hg occurred.Thus, an acute shift of the oxyhemoglobin curve to the left was accompanied by a significant decrease in the mixed venous P(O2) without evidence of acidosis, decreased oxygen consumption, or a compensatory increase in cardiac output. PMID- 4199606 TI - A simple trauma model in the rat. PMID- 4199607 TI - Exertional arrhythmia and nitgroglycerin. PMID- 4199608 TI - Malignant pleural disease. A radiotherapeutic approach to the problem. PMID- 4199609 TI - [Hygienic studies on pesticide residues. 3. Determination of organochlorine pesticide residues in human tissues and other samples]. PMID- 4199610 TI - Immunological identification of human semen. PMID- 4199611 TI - Filters for intravenous alimentation. PMID- 4199612 TI - Specificity of precipitating antibodies in immunological identification of antihaemophilic factor. PMID- 4199613 TI - Tyrosinase activity in subcellular fractions of black and albino mice. PMID- 4199614 TI - Aspirin inhibition of in vitro osteolysis stimulated by parathyroid hormone and PGE1. PMID- 4199615 TI - Prostaglandin regulation of airway smooth muscle tone. PMID- 4199616 TI - An evaluation of five percent sulfamylon cream in control of experimental burn wound sepsis. PMID- 4199617 TI - Ocular anomalies in malformation syndromes. PMID- 4199618 TI - Wide-angle holography of the eye. PMID- 4199619 TI - Recovery of the rod and cone cells after photic injury. PMID- 4199620 TI - Tuberculosis of the tongue. PMID- 4199621 TI - Ketosis. PMID- 4199622 TI - Regulation of erythropoiesis by androgens. PMID- 4199623 TI - [Evaluation of actual efficiency in trotting horses]. PMID- 4199624 TI - On the transferrin concentration in blood serum of growing calves and in bovine colostrum. PMID- 4199625 TI - The composition of bovine udder secretion during the first half of the dry period. PMID- 4199626 TI - [Corpus luteum cyst in cattle. Micromorphology and discussion on its origin]. PMID- 4199627 TI - Studies on the gestational changes in the buffalo uterus. I. The histo morphological changes. PMID- 4199628 TI - Variations in thyroid status of the buffalo during the estrous cycle, pregnancy and in conditions of ovarian abnormalities. PMID- 4199629 TI - [Cell picture of porcine cerebrospinal fluid under normal conditions and following latex injection below arachnoidea]. PMID- 4199630 TI - Congenital cerebellar ataxia in the gotland pony breed. PMID- 4199631 TI - [Germinal transmission of sigma virus in Drosophila melanogaster. I. The effect of temperature on the vertical transmission by female flies originally infected by the paternal gamete exclusively]. PMID- 4199632 TI - Comparative studies on glycerol 3-phosphate dehydrogenase in bees and wasps. PMID- 4199633 TI - Purification and crystallization of three isoenzymes of malate dehydrogenase from Zea mays seed. PMID- 4199634 TI - The synthesis of 3-nonaprenyl-4-hydroxybenzoate in rat liver mitochondria: the effect of Ca2 , Mg2+, chelators, and bacitracin on the activity of p hydroxybenzoate-polyprenyl transferase. PMID- 4199635 TI - Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. 3. Biosynthesis of carbonic anhydrases in bone marrow erythroid cells and peripheral blood reticulocytes of Macaca nemestria. PMID- 4199636 TI - The pancreatic -cell recognition of insulin secretagogues. VII. Binding and permeation of chloromercuribenzene-p-sulphonic acid in the plasma membrane of pancreatic -cells. PMID- 4199637 TI - The Donnan effect in tobacco mosaic virus and its components. PMID- 4199638 TI - Preparation and partial fractionation of nonhistone chromosomal proteins from human diploid fibroblasts. PMID- 4199642 TI - Shock, cerebral hypoxia, and pulmonary vascular control: the centrineurogenic etiology of the respiratory distress syndrome. PMID- 4199643 TI - Effects of long-term adjuvant chemotherapy with cyclophosphamide (NSC-26271) for radically resected bronchogenic carcinoma. PMID- 4199644 TI - Results of combination treatment of lung cancer patients: surgery plus radiotherapy and surgery plus chemotherapy. PMID- 4199645 TI - Chemotherapy for lung cancer at the Institute of Experimental and Clinical Oncology, Academy of Medical Sciences, USSR. PMID- 4199646 TI - Trauma as a cause of epilepsy in childhood. PMID- 4199648 TI - Test for missynthesis of lactate dehydrogenase in aging mice by use of a monospecific antibody. PMID- 4199647 TI - The localization of DNA ligase in the chromatin of animal cells. PMID- 4199649 TI - Age-associated changes in viability genetic loads of Drosophila melanogaster. PMID- 4199650 TI - Heat tolerance changes with age in normal and irradiated Drosophila melanogaster. PMID- 4199651 TI - Testing of rifampicin on possible genetic effects on Drosophila melanogaster and human leukocyte chromosomes in vitro. PMID- 4199652 TI - A method for freezing living ovaries of Drosophila melanogaster larvae and its application to the storage of mutant stocks. PMID- 4199653 TI - Distribution of 5S RNA in the liver of the South American rattlesnake, Crotalus durissus terrificus. PMID- 4199654 TI - Effects of nicotine and arousal on the monkey electroencephalogram. PMID- 4199656 TI - Separation of peptides according to charge by gel filtration in the presence of ionized detergents. PMID- 4199655 TI - [Idiotypy of antibodies against human serum albumin in immunized rabbit serum, which are directed against different regions of this antigen]. PMID- 4199657 TI - Nonhistone chromatin protein phosphorylation during azo-dye carcinogenesis. PMID- 4199658 TI - Fracture faces of zonulae occludentes from "tight" and "leaky" epithelia. AB - Epithelia vary with respect to transepithelial permeability. In those that are considered "leaky", a large fraction of the passive transepithelial flux appears to follow the paracellular route, passing across the zonulae occludentes and moving down the intercellular clefts. In "tight" epithelia, the resistance of the paracellular pathway to passive flux is greatly increased. To see whether differences in the morphology of the zonula occludens could contribute to this variability in leakiness among epithelia, replicas of zonulae occludentes in freeze-fractured material from a variety of tight and leaky epithelia were examined. The junctions appear as a branching and anastomosing network of strands or grooves on the A and B membrane fracture faces, respectively. It was found that the zonula occludens from a "very leaky" epithelium, the proximal convoluted tubule of the mouse kidney, is extremely shallow in the apical-basal direction, consisting in most places of only one junctional strand. In contrast, the "very tight" frog urinary bladder exhibits a zonula occludens that is relatively deep (>0.5 microm) in the apical-basal direction, and consists of five or more interconnected junctional strands interposed between luminal and lateral membrane surfaces. Epithelia of intermediate permeabilities exhibited junctions with intermediate or variable morphology. Toad urinary bladder, mouse stomach, jejunum, and distal tubule, rabbit gallbladder, and Necturus kidney and gallbladder were also examined, and the morphological data from these epithelia were compared to physiological data from the literature. PMID- 4199659 TI - Complementary chromatic adaptation in a filamentous blue-green alga. AB - Fluorescent and red light environments generate greatly different patterns of pigmentation and morphology in Fremyella diplosiphon. Most strikingly, red illuminated cultures contain no measurable C-phycoerythrin and have a mean filament length about 10 times shorter than fluorescent-illuminated cultures. C phycoerythrin behaves as a photoinducible constituent of this alga. Spectrophotometric and immunochemical procedures were devised so that C phycoerythrin metabolism could be studied quantitatively with [(14)C] phenylalanine pulse-chased cultures. Transfer of red-illuminated cultures to fluorescent light initiates C-phycoerythrin production by essentially de novo synthesis. C-phycoerythrin is not degraded to any significant extent in cultures continuously illuminated with fluorescent light. Transfer of fluorescent illuminated cultures to red light causes an abrupt cessation of C-phycoerythrin synthesis. The C-phycoerythrin content of cultures adapting to red light decreases and subsequently becomes constant. Loss of C-phycoerythrin is not brought about by metabolic degradation, but rather by a decrease in mean filament length which is effected by transcellular breakage. In this experimental system, light influences intracellular C-phycoerythrin levels by regulating the rate of synthesis of the chromoprotein. PMID- 4199660 TI - Sedimentation velocity characterisation of the cell cycle of granulocytic progenitor cells in monkey hemopoietic tissue. PMID- 4199661 TI - Surrogate rehabilitation of monkeys reared in total social isolation. PMID- 4199662 TI - Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locus. PMID- 4199663 TI - Adenovirus DNA. IV. Topology of adenovirus genomes. PMID- 4199664 TI - [Recording the unit activity of vagal motor fibers innervating the baboon esophagus]. PMID- 4199665 TI - Further observation on the difference between Tyzzer's organisms from mice and those from rats. PMID- 4199666 TI - Immunologic reactions of filaria-free beagle sera to Dirofilaria antigen. PMID- 4199667 TI - [Multiple schwannoma with digestive localizations (Von Recklinghausen's disease). Apropos of a familial case]. PMID- 4199668 TI - Influence of fungicides on mycotoxin production by Alternaria mali. PMID- 4199670 TI - [Phakomatosis]. PMID- 4199669 TI - Mycoflora in cystic fibrosis: some ecologic aspects of Pseudomonas aeruginosa and Candida albicans. PMID- 4199671 TI - Preparation and specificity of antibodies to 15-keto-prostaglandin F2alpha. PMID- 4199672 TI - Inhibition of abortion and fetal death produced by endotoxin or prostaglandin F2alpha. PMID- 4199673 TI - Possible mode of action of prostaglandins. V. Differential effects of prostaglandin F2 before and after the establishment of placental physiology in pregnant rats. PMID- 4199674 TI - Absorption of prostaglandin E2 and uterine sensitivity of the non-pregnant and pregnant monkey in vivo. PMID- 4199675 TI - Release of prostaglandins by the I.U.C.D. PMID- 4199676 TI - Levels of 13,14-dihydro-15-keto-PGF in biological fluids as measured by radioimmunoassay. PMID- 4199677 TI - Effect of intraventricularly administered prostaglandin E1 on the electrical activity of cerebral cortex and behavior in the unanesthetized monkey. PMID- 4199678 TI - Effect of polyphloretin phosphate and 7-oxa-13-prostynoic acid on the vasoactive actions of prostaglandin E2 and 5-hydroxytryptamine on isolated human umbilical arteries. PMID- 4199679 TI - Prostaglandin and eye. PMID- 4199680 TI - Effect of aspirin upon male mouse fertility. PMID- 4199681 TI - [Theory and practice of antenatal care of the fetus]. PMID- 4199682 TI - Substrate non-specificity of Streptococcus faecalis azoreductase. PMID- 4199683 TI - The metabolism of 3-((5-methyl-5H-as-triazino(5,6-b)-indol-3-yl)amino)-1-propanol (SK&F 21687). A Potent antiviral. PMID- 4199684 TI - The effect of cyclophosphamide (endoxan) on histoenzymatic reactions in the liver. II. Studies on liver regeneration during cyclophosphamide administration. PMID- 4199685 TI - Polarographic investigation on Pb++ trapping by subcellular fractions of rat liver. PMID- 4199686 TI - A histochemical study of few enzymes in the neoplastic liver of Corvus spledens (Vieillot). PMID- 4199687 TI - A histochemical study on the dihydrofolate reductase activity in leukemia. PMID- 4199688 TI - [Glycogen detection using alizarin blue S]. PMID- 4199689 TI - [Immune cytological demonstration of in vitro formed immunoglobulins in mitosis from peripheral blood lymphocytes of healthy persons and from synovial fluid of rheumatoid arthritis]. PMID- 4199690 TI - Histochemical analysis of the neurosecretory product in fishes. PMID- 4199691 TI - Mucopolysaccharide histochemistry of Musca domestica. VI. The structure and development of chitin. PMID- 4199692 TI - [Extensibility of enterochromaffine cell system concept to plants. I. Histochemical knowledge of the stings of the nettle (Urtica dioica L.)]. PMID- 4199693 TI - Sequential staining for the correct histochemical localization of lactic dehydrogenase activity in formaldehyde-fixed frozen sections of a mixed muscle. PMID- 4199694 TI - [Pathogenesis of odontogenic cysts; correlation of morphological and immunological findings]. PMID- 4199695 TI - [Demonstration of naphthol-AS-D-chloroacetate esterase and its dependence on the fixating agent]. PMID- 4199696 TI - [The effect of swelling in quantitative polarization studies]. PMID- 4199697 TI - Comparison of Bacillus thuringiensis with other bacillus species based on enzymoserological examinations of their proteolytic enzymes. PMID- 4199698 TI - Serum complement in normal pregnancy and pre-eclampsia. PMID- 4199699 TI - Reservoir hosts of cutaneous leishmaniasis among Panamanian forest mammals. PMID- 4199700 TI - Cerebral filariasis in Rhodesia--a zoonotic infection? PMID- 4199701 TI - Effects of new laser systems on the skin. PMID- 4199702 TI - Ultrastructure of a pilar tumor. PMID- 4199703 TI - Kurotori virus: a virus newly isolated from Anopheles sinensis and pathogenic to mice. I. Isolation and properties. PMID- 4199704 TI - Effects of chelating agents on the initial interaction of phytohemagglutinin with lymphocytes and the subsequent stimulation of amino acid uptake. PMID- 4199705 TI - Maleyl-alpha-lactalbumin as lactose synthetase specifier protein. PMID- 4199706 TI - Studies on the cell surface maltase of the rabbit renal cortex. PMID- 4199707 TI - Inhibition of lectin agglutinability by fixation of the cell surface membrane. PMID- 4199708 TI - Airways narrowing in exercise in normal subjects and the effect of disodium cromoglycate. PMID- 4199709 TI - Tuberculosis of the male urethra. PMID- 4199710 TI - Pharmacokinetic studies on minocycline in man. PMID- 4199711 TI - [Improvement of management system of experimental animals at National Cancer Center]. PMID- 4199712 TI - Sub-units of N-acetylglucosaminidases. PMID- 4199713 TI - Phospholipase C (Bacillus cereus) acts only at the inner surface of the erythrocyte membrane. PMID- 4199714 TI - Consequences of smallpox vaccination in leprosy patients. AB - This study illustrates the consequences of smallpox revaccination in 45 lepromatous, 28 tuberculoid, and 47 normal individuals. Results obtained with intradermal inoculations indicated that the patients with leprosy were associated with a relative anergy against the vaccinia virus, the anergy being minimal in the tuberculoid leprosy but marked in the cases with lepromatous leprosy. Major vaccinial reactions were observed more often in patients with lepromatous leprosy than in the controls or patients with tuberculoid leprosy. Furthermore in a patient with lepromatous leprosy, vaccinia necrosum also developed. The smallpox vaccination with live virus also appeared as a provocative factor for the precipitation of lepra reaction in the lepromatous leprosy cases. After 3 weeks of vaccination, the frequency of the specific humoral antibody response was the same in the tuberculoid patients and controls while it was higher in the cases with lepromatous leprosy. The prevaccination titer of total hemagglutination inhibition antibody was significantly higher in the lepromatous leprosy cases. However, the postvaccinial, humoral antibody response of the lepromatous patients was of the same magnitude as that observed in the normal individuals, and it was mainly due to a 2-mercaptoethanol-resistant antibody. PMID- 4199715 TI - Association of group B coxsackie viruses with cases of pericarditis, myocarditis, or pleurodynia by demonstration of immunoglobulin M antibody. AB - Tests for immunoglobulin M (IgM) antibody to group B coxsackieviruses were performed on sera from 259 patients with a clinical diagnosis of pericarditis, myocarditis, or pleurodynia on whom there were no definitive serological or virus isolation findings to establish a viral etiology, and on 259 "control" patients with clinical diagnoses of viral or mycoplasmal pneumonia or pneumonitis. IgM antibodies to coxsackievirus types B1, B3, B4, B5, and B6 were detected by a micro-immunodiffusion technique, and antibodies to virus type B2 were detected by reduction of neutralizing antibodies with ethanethiol. Of the patients with pericarditis, myocarditis, or pleurodynia, 27% (70) had IgM antibody to group B coxsackieviruses, as compared with 8% in the control group. On retrospective review of the clinical diagnosis, some of the patients in the control group with IgM antibody were found to have had additional clinical findings which could be attributed to a coxsackievirus infection. Coxsackievirus IgM antibody was demonstrable in 30% of 113 patients in the study group for whom virus isolation had been attempted with negative results. The presence of coxsackievirus IgM is discussed in relation to the time of serum collection, age of the patients, and month of onset of illness. PMID- 4199717 TI - Antimycobacterial effect of lysates prepared from immunologically activated macrophages. AB - Lysates or heptane extracts of peritoneal (P) and alveolar (A) normal macrophages (N-M), immune macrophages (I-M), and immune-activated macrophages (IA-M) were examined for antimycobacterial activity by the agar-plate diffusion test. This test has been found suitable to reveal the antibacterial activity in 3-day incubated, but not in freshly prepared, lysates. Results showed that materials of IA-AM or I-AM and of IA-PM exerted antimycobacterial effects, whereas materials of N-PM, I-PM, and of N-AM were usually inactive. Antimycobacterial activity of lysates of AM was stronger than that of PM. The formation of antibacterial factors during an incubation of M lysates, the solubility of the factors in heptane, and various other characteristics suggested that the antimycobacterial effect was caused by the formation of toxic levels of non-esterified fatty acids. M lysates exerted equal activities against BCG, H(37)Ra, and H(37)Rv strains of tubercle bacilli. The presence of antimycobacterial activity in lysates prepared from IA-M of either BCG- or BCG-sensitized animals indicated that the potential to generate antimycobacterial activity is associated with the state of delayed hypersensitivity and the state of activation of M. PMID- 4199716 TI - Relative immunogenicity of streptomycin-sensitive and -resistant strains of BCG. AB - Normal, specific pathogen-free mice were vaccinated intravenously with increasing amounts of a streptomycin-resistant variety of BCG Tice (BCG SM(R)). The behavior of BCG SM(R) in the lungs, liver, and spleen was followed quantitatively for up to 50 days. One or two intravenous doses of 10(6) viable organisms were steadily eliminated from the tissues without producing detectable tuberculin sensitivity or raising resistance to a subsequent challenge with Mycobacterium tuberculosis strain Erdman. But mice receiving six weekly injections of 10(6) viable BCG SM(R) or a single injection of 10(6) BCG SM(R) by the intravenous route did develop effective levels of antituberculous resistance. Heat inactivation of the BCG SM(R) inoculum removed the organism's protective activity which could, however, be restored by incorporation of the organisms into Freund adjuvant. The ability of living BCG SM(R) to induce an effective antituberculous resistance when introduced into the tissues in an appropriate manner is discussed in terms of the mechanism of antituberculous immunity. PMID- 4199718 TI - Ribosomal vaccines. II. Specificity of the immune response to ribosomal ribonucleic acid and protein isolated from Salmonella typhimurium. AB - Ribosomal proteins isolated from Salmonella typhimurium were effective in inducing immunity in mice. This immunity was specific since animals immunized with ribosomal proteins from S. typhimurium were not protected against challenge with S. cholerae-suis or S. enteritidis. Immunity was evident as early as 5 days after immunization. Ribosomal ribonucleic acid (RNA) failed to provide any effective immunity in mice. Polyinosinic acid: polycytidylic acid (poly I: C) induced a rapid, short-lived immunity to all three Salmonella species. In contrast, ribosomal RNA failed to elicit any rapid nonspecific response to infection. PMID- 4199719 TI - Measurement of antibody-reactive toxin antigen during experimental staphylococcal B enterotoxemia. AB - Staphylococcal enterotoxin B (SEB) injected intravenously is rapidly cleared from the circulation and deposited in tissues. Type-specific antiserum administered after toxin has left the circulation can influence the course of enterotoxemia, and this observation suggests that toxin antigens may either be returned to the circulation or reside on cell surfaces readily available to antibody. If SEB toxin or its fragments regain access to the extracellular space, they might react with circulating antibody and be detected and quantitated by the reduction in antibody titer. Accordingly, 1 h after toxin or saline injection, animals were given type-specific enterotoxin B antiserum, and the difference in titers between the animals was used to compute the amount of enterotoxin immediately available to antibody. Further, by measuring differences in titers over a 48-h period, an estimate was made of the amount of SEB antigen that gained access to antibody. The data indicate that rats, which are relatively resistant to the lethal effects of enterotoxin, clear toxin from the circulation promptly and that very little toxin reenters the circulation. Monkeys, who are highly susceptible to SEB, also clear toxin promptly. However, in contrasts to rats, monkeys have greater quantities of SEB immediately available to antibody and in addition return significant quantities of toxin antigens to the extracellular space. PMID- 4199720 TI - Toxinogeny in Corynebacterium diphtheriae after loss of catalase, cystinase, or deoxyribonuclease activity. AB - The relationship of catalase, cystinase, and deoxyribonuclease activity to toxinogeny in Corynebacterium diphtheriae was examined. Mutants deficient in each activity were isolated after mutagenization of strain C4 with nitrosoguanidine. All mutants were converted to toxinogeny after lysogenization with beta converting phage, thus establishing that there is no absolute link between toxin production and these enzymatic activities. No differences were observed in the rate of lysogenization of the mutants by beta-converting phage over that of the parental strain. However, the data suggest that catalase mutants lysogenic for beta phage are generally induced at a higher rate than the parental strain after irradiation with ultraviolet light. Cystinase mutants vary widely in their rate of induction whereas the deoxyribonuclease mutants are similar to the parental strain. The relationship of these results to the production of toxinogenic strains is discussed. PMID- 4199721 TI - Serology of Streptococcus sanguis: localization of antigens with unlabeled antisera. AB - A new technique for the electron microscope localization of bacterial surface antigens, using unlabeled antisera, has been developed. This technique, called the "immuno-coating reaction" was applied to serological studies of Streptococcus sanguis, using antisera which had been shown to be specific for this species by gel diffusion analysis. The results of the immuno-coating reaction confirmed the specificity of the antisera for S. sanguis. In addition, the data indicate that some of the antigens responsible for the reaction were proteins which formed filamentous processes on the surface of the cell. PMID- 4199722 TI - Origin and development of kinetosomes in Oxytricha fallax. PMID- 4199723 TI - The ultrastructural effects of excess maternal vitamin A on the primitive streak stage rat embryo. PMID- 4199724 TI - New sensitive assay for phosphatidylserine decarboxylase based on the detection of CO2 from nonradiolabeled phosphatidylserine. AB - A new rapid assay for phosphatidylserine decarboxylase, which is sensitive in the nanomolar range, is described. Synthesis of radiolabeled phosphatidylserine for use as a substrate is not required, since the assay, unlike previous ones, is based on the detection of CO(2) liberated from unlabeled phosphatidylserine. The assay employs a gas chromatographic procedure for the analysis of methane formed by catalytic conversion of the CO(2) produced as a product of the enzymatic reaction. PMID- 4199725 TI - Immunology of the gastrointestinal tract. I. PMID- 4199726 TI - A fatal x-linked recessive reticuloendothelial syndrome with hyperglobulinemia. X linked recessive reticuloendotheliosis. PMID- 4199727 TI - Disseminated intravascular coagulation in a newborn infant with Listeria sepsis. PMID- 4199728 TI - Economics and medicos. PMID- 4199729 TI - Radioassay and the thyroid gland. PMID- 4199730 TI - Detection of virus antigens: hepatitis B antigen. PMID- 4199731 TI - The physiology of growth hormone regulation: pre- and postimmunoassay eras. PMID- 4199732 TI - Depressive disorders: toward a unified hypothesis. AB - Our scientific understanding of psychiatric syndromes, including the phenomena of depression, has been hampered because of: (i) the use of metapsychological concepts that are difficult to test; (ii) methodological and linguistic barriers that prevent communication among psychoanalysts, behaviorists, experimental psychologists, and psychiatrists; and (iii) the reluctance of psychiatrists to accept animal models as possible approximations of certain aspects of human psychopathology. We have attempted to demonstrate that the animal models simulate some of the central features of clinical depression (for example, helplessness and object loss), thereby allowing one to rigorously investigate them from developmental, behavioral, and biochemical perspectives. The object loss model, as a concrete version of a metapsychological-psychoanalytic concept, has enabled primatologists to study the disruption of an attachment bond. The behavioral model accommodates this concept to a broader generalization: loss of reinforcement or loss of control over reinforcement. We have reviewed the evidence that these processes involve the diencephalic centers of reward or reinforcement, thereby permitting integration of the psychoanalytical and behavioral formulations with the biochemical hypotheses. Also, we have presented data strongly suggesting that the breaking of an attachment bond in the primate represents significant loss of reinforcement that induces helplessness and disrupts motivated behavior. Finally, we have argued that the depressive syndrome could be caused by interactions of genetic, chemical, developmental, and interpersonal factors, all of which impinge on the diencephalic centers of reinforcement. PMID- 4199733 TI - Experimental subacute spongiform virus encephalopathies in primates and other laboratory animals. AB - The host range of subacute spongiform virus encephalopathies is described. The asymptomatic incubation period and the duration of the illnesses in various species of animal hosts is discussed along with information on additional species of Old World and New World monkeys and the domestic cat, which have been shown to be susceptible to subacute spongiform virus encephalopathies. PMID- 4199734 TI - Induction of an enzyme in genetically deficient rats after grafting of normal liver. AB - Tissue from normal rat livers was grafted onto the livers of rats that were genetically deficient in bilirubin uridine diphosphate glucuronyltransferase activity. Twelve weeks after the grafting operation, the liver of the recipient rats had bilirubin uridine diphosphate glucuronyltransferase activity. PMID- 4199735 TI - Instrumental conditioning of large-magnitude, daily, 12-hour blood pressure elevations in the baboon. AB - Blood pressure and heart rate were monitored continuously in four baboons during extended exposure to a daily 12-hour conditioning procedure providing food and shock-avoidance as contingent consequences of prespecified increases in diastolic blood pressure. Sustained and significant increases (30 to 40 mm-Hg) in both systolic and diastolic blood pressure were maintained throughout the daily 12 hour conditioning sessions, accompanied by elevated heart rates. PMID- 4199736 TI - Controlled biliary drainage for large injuries of the liver. PMID- 4199737 TI - Functional and morphologic changes after lung allografting in baboons. PMID- 4199738 TI - [Hypothalamus hormone]. PMID- 4199739 TI - Adult versus infant brain damage: behavioral and electrophysiological effects of striatectomy in adult and neonatal rabbits. PMID- 4199740 TI - [Avoiding the late tracheal complications following long term intubation for artificial respiration: a new method of inflating the cuff]. PMID- 4199741 TI - Structure and function of natural proteinase inhibitors. PMID- 4199742 TI - [Serological studies on cattle in catchment area of Kabete (Kenia). 2. Determination of antibodies against Mycobacterium paratuberculosis, Brucella, Salmonella, Pasteurella multocida, Listeria and Leptospira]. PMID- 4199743 TI - Immunological study of carcinoembryonic antigen (CEA) and a related glycoprotein. AB - A comparison has been made of the immunological properties of CEA (carcinoembryonic antigen) and another perchloric acid-soluble macromolecule which occurs in colonic and certain other carcinomata and which is here termed CEX. By using a variety of antisera it was shown that the two substances share common antigenic groups as well as having characteristic ones of their own. These latter groups have enabled the preparation of (a) antisera which give a gel diffusion line only with CEA and (b) and antiserum which gives a line only with CEX. No immunological difference could be found between CEX and the NGP of Mach or the NCA of von Kleist and Burtin. CEX was found in foetal gut, in plasma and associated with CEA in virtually all the tissues and fluids in which the latter occurs; the two appear to go hand-in-hand and no proof was found that CEX is either less or more cancer specific than CEA-it is merely found in greater quantity; neither substance showed absolute cancer specificity. The usefulness of a radioimmunoassay for CEX is discussed, and also the possibility of interference by CEX in the radioimmunoassay for CEA. Evidence of two molecular species of CEA has been found. PMID- 4199744 TI - Trial of chloramphenicol for meningitis in northern savanna of Africa. AB - In a controlled trial chloramphenicol proved as effective and much cheaper than penicillin for the treatment of group A meningococcal meningitis in Zaria, Nigeria. A short course of five days cured most patients. Adults and older children were soon able to take chloramphenicol by mouth, which reduced the cost and simplified treatment.It is suggested that chloramphenicol is a suitable alternative to sulphonamides for the treatment of meningococcal meningitis in those parts of Africa where the organism is sulphonamide-resistant. PMID- 4199745 TI - Significance of Pseudomonas aeruginosa in sputum. AB - Pseudomonas aeruginosa was isolated from the sputum of 63 patients. In 34 the organism was a commensal, in 14 it was causing chronic suppuration, and in 10 had interfered with antibiotics directed against other organisms and was thus indirectly pathogenic. In five patients, all of whom died, the organism could have been acting as an acute pathogen. Attempts should be made to determine the nature of the organism's pathogenicity in a given patient and appropriate therapy withheld or administered accordingly. PMID- 4199746 TI - Multiple precipitation of sera containing monoclonal IgG proteins in radial immunodiffusion. PMID- 4199747 TI - [Effects of synthetic thyrotropin releasing hormone on values of serum TSH in children]. PMID- 4199748 TI - [Inheritance of spike-wave complexes and febrile seizures in three generations]. PMID- 4199749 TI - Visually evoked responses in the rat, guinea pig, cat, monkey, and man. PMID- 4199750 TI - Delayed response deficits in squirrel monkeys with unilateral lesions in the midbrain reticular formation. PMID- 4199752 TI - Morphologic sex differences in primate brain areas involved in regulation of reproductive activity. PMID- 4199751 TI - Hippocampal lesions produced by prolonged seizures in paralyzed artificially ventilated baboons. PMID- 4199753 TI - Activation of nisin production by UV-irradiation in a nisin-producing strain of Streptococcus lactis. PMID- 4199754 TI - Regeneration of Drosophila melanogaster male leg disc fragments in sugar fed female hosts. PMID- 4199755 TI - The biological effects of the bark of Saccoglottis gabonensis Urban (Humiriaceae) on microorganisms. PMID- 4199756 TI - Australia antigen: current concepts. PMID- 4199757 TI - Conformational changes following interaction between retinol isomers and human retinol-binding protein and between the retinol-binding protein and prealbumin. PMID- 4199758 TI - Interactions of all-trans, 9-, 11-, and 13-cis-retinal, all-trans-retinyl acetate, and retinoic acid with human retinol-binding protein and prealbumin. PMID- 4199759 TI - Structure of a pentahexosylceramide (Forssman hapten) from canine intestine and kidney. PMID- 4199760 TI - Combined action of beta-lactum antibiotics against gram-negative bacilli. PMID- 4199761 TI - Experimental study of latency in typhus infection. PMID- 4199762 TI - Immunological reactivity of chloramphenicol. I. Detection of antibodies, determination of levels and hypersensitivity. PMID- 4199763 TI - [Structure and biosynthesis of chrysogine, a metabolite of Penicillium chrysogenum]. PMID- 4199764 TI - [Symposium: clinical studies on duodenal diverticulosis]. PMID- 4199765 TI - [Serum immunoglobulins in certain intestinal diseases]. PMID- 4199767 TI - The gonococcus--a tough bug to grow. PMID- 4199766 TI - [Australia antigen in the patient on chronic hemodialysis]. PMID- 4199768 TI - Diazepam as therapy for convulsive seizures precipitated by chemical intoxicants. PMID- 4199769 TI - Metabolic acidosis in infants infused with commercial amino acid mixtures. PMID- 4199770 TI - Effects of maternal employment on the child. II. PMID- 4199771 TI - [Clinical and immunological studies on cryoglobulins in connective tissue diseases]. PMID- 4199772 TI - The genetics of blue-green algae. PMID- 4199773 TI - Behavioral development after forelimb deafferentation on day of birth in monkeys with and without blinding. AB - Four infant monkeys underwent somatosensory deafferentation of both forelimbs within hours after birth. Ambulation, climbing, and reaching toward objects developed spontaneously in each case. Thumb-forefinger prehension could be trained by operant shaping methods. Two infants deafferented at birth and blinded by eyelid closure were retarded in motor development by only 1 to 2 weeks. Results indicate that topographic sensory feedback and autogenetic spinal reflexes are not necessary after birth for the development of most types of movement performed by the forelimb musculature in monkeys. PMID- 4199774 TI - Chlorhexidine as an inhibitor of pure bacterial and fungal cultures and dental plaque micro-organisms in sterilized saliva. PMID- 4199775 TI - Comparative biology of prokaryotic resting cells. PMID- 4199776 TI - Histochemical interpretation of fluorescein angiogram. II. Background fluorescence and macular dark spot. PMID- 4199777 TI - Experimental manipulation of desmosome structure. PMID- 4199778 TI - Ecology of entomogenous viruses and fungi. PMID- 4199779 TI - Bacteria, spirochetes, and rickettsia as insecticides. PMID- 4199780 TI - Increased aggregation of C-phycocyanin produced by phenol and benzene. PMID- 4199781 TI - The characterization of the RNAs and aminoacyl-tRNA synthetases of the blue-green alga, Anacystis nidulans. PMID- 4199782 TI - Fractionation of ribonucleic acid by centrifugation in mixed sodium-potassium iodide density gradients. PMID- 4199783 TI - A new intratypic variant of coxsackie B6 virus. PMID- 4199784 TI - [Results of replacement of the mitral valve (165 prostheses)]. PMID- 4199785 TI - [Value of fluorescence in the macroscopic delimitation of experimental acute myocardial ischemia before and after revascularization]. PMID- 4199786 TI - [Accelerated idioventricular rhythms (or slow ventricular tachycardia)]. PMID- 4199787 TI - [The cardiovascular system in hereditary spino-cerebellor degeneration]. PMID- 4199788 TI - [Obstructive cardiomyopathy and atrio-ventricular conduction disorder]. PMID- 4199789 TI - [Assessment of myocardial function]. PMID- 4199790 TI - [The syndrome of supravalvular aortic stenosis, mental retardation and peculiar facies]. PMID- 4199791 TI - [A case of inflammatory complete atrio-ventricular block fatal in 10 days]. PMID- 4199792 TI - [Anginal attack with systolic murmur]. PMID- 4199793 TI - [Syphilitic angina pectoris. Angina pectoris in syphilis. Myocardial infarction after selective coronarography. Surgical ostial disobliteration]. PMID- 4199794 TI - [Mitral Starr valve disinsertion. Clinical diagnosis]. PMID- 4199795 TI - Screening tests for argininosuccinic aciduria, orotic aciduria, and other inherited enzyme deficiencies using dried blood specimens. PMID- 4199796 TI - Alkaline phosphatase of Drosophila melanogaster. I. Partial purification and characterization. PMID- 4199797 TI - Morphogenic effects of halogenated thymidine analogues on Drosophila. I. Quantitative analysis of lesions induced by 5-bromodeoxyuridine and 5 fluorouracil. PMID- 4199798 TI - Esterase polymorphisms in Microtus ochrogaster: interaction and linkage. PMID- 4199799 TI - Induction of null-activity mutants for the acid phosphatase-1 gene in Drosophila melanogaster. PMID- 4199800 TI - Levels of RNA and DNA in Drosophila melanogaster at different stages of development: a comparison between one bobbed and two phenotypically non-bobbed stocks. PMID- 4199801 TI - Molecular pathology of ceruloplasmin. PMID- 4199802 TI - Distribution of erythrocyte carbonic anhydrase B-type alleles in Japanese farm horses. PMID- 4199803 TI - Mitochondria and chloroplasts as descendants of prokaryotes. PMID- 4199804 TI - Genome amplification and gene expression in the ciliate macronucleus. PMID- 4199805 TI - Conformational studies of nucleoprotein. Circular dichroism of deoxyribonucleic acid base pairs bound by polylysine. PMID- 4199806 TI - Cross-linking of elongation factor EF-G to the 50S ribosomal subunit of Escherichia coli. PMID- 4199807 TI - Neurofibrosarcoma of the orbit (malignant change in a plexiform neurofibromatosis). PMID- 4199808 TI - Effect of cocaine on Na channel in toad skin. PMID- 4199809 TI - Differential cytotoxicity of activated lymphocytes on allogeneic and xenogeneic target cells. II. Activation by phytohemagglutinin. PMID- 4199810 TI - Survival and function of bursa-derived cells in bursectomized chickens. PMID- 4199812 TI - [Thermolability of 28S ribosomal RNA from a reseedable culture of Drosophila melanogaster cells]. PMID- 4199811 TI - Replicating DNA molecules from eggs of Drosophila melanogaster. PMID- 4199813 TI - Immunological analysis of acidic proteins in the chromatin of Ehrlich ascites tumor cells. PMID- 4199814 TI - Disappearance of multiple esophageal diverticula following treatment of esophagitis: serial endoscopic, manometric, and radiologic observations. PMID- 4199815 TI - [The palatopharyngeal muscle of mammals]. PMID- 4199816 TI - [Use of the hand in a selected group of primates]. PMID- 4199817 TI - Biosynthesis of the piperidine nucleus. Incorporation of chirally labeled (1 3H)cadaverine. PMID- 4199818 TI - Automated photometric microbiological assay for monensin in poultry rations. PMID- 4199819 TI - Infrared studies of DDT, structurally related halogenated pesticides, and some metabolites. PMID- 4199820 TI - Collaborative study of a colorimetric determination of nitroglycerin in sublingual tablets. PMID- 4199821 TI - Turbidimetric evaluation of bacterial culture resistance in disinfectant testing. PMID- 4199823 TI - [Simplified method of differentiation of glucose non-fermentative, gram-negative rods in the clinical material]. PMID- 4199822 TI - [Pharyngeal hemolytic streptococci in school children. 2. Group and type distribution in Okinawa and Tokyo Districts]. PMID- 4199824 TI - [Clinical and serological studies on a further attenuated live measles virus AIK vaccine]. PMID- 4199825 TI - [Isolation method of anaerobic bacteria by glove box procedure]. PMID- 4199826 TI - [Studies on the thyroid function in the aged as viewed from TRH-TSH system]. PMID- 4199827 TI - [Recent advances in the isolation of Pseudomonas aeruginosa and related gram negative rods]. PMID- 4199828 TI - [Current status of experimental studies on Pseudomonas aeruginosa infection]. PMID- 4199829 TI - [Pseudomonas aeruginosa. I. Isolation of P. aeruginosa in nature and animals, with special reference to mice and guinea pigs]. PMID- 4199830 TI - The death rate of lysogenic bacteria after ultraviolet induction follows Gompertz's law. PMID- 4199831 TI - Recent evidence on tRNA and tRNA acylase-mediated cellular control mechanisms: a review. PMID- 4199832 TI - [Possibilities in the use of thyrotropin-releasing hormone (TRH)]. PMID- 4199833 TI - [Infection of crural ulcers with Pseudomonas aeruginosa in a dermatological clinic. A study of the role of some potentially infectious strains]. PMID- 4199834 TI - [Double blind test of hydergine in the aged]. PMID- 4199835 TI - [Qualitative and quantitative variations in amniotic fluid proteins during pregnancy]. PMID- 4199836 TI - [Unusual gastrointestinal and cardiovascular complications in a case of Ehlers Danlos syndrome]. PMID- 4199837 TI - [Effect of various urea rations on the histology and histotopochemistry of glycogens and fats in the liver and kidneys of heifers and their calves]. PMID- 4199838 TI - [White blood picture in highly pregnant heifers before parturition and during puerperium]. PMID- 4199839 TI - [Increased salivation as a result of the insertion of a ring preventing tongue playing as the cause of alkalosis of proventricular contents in cattle]. PMID- 4199840 TI - [Activity of dehydrogenases in ruminal fluid of clinically healthy sheep]. PMID- 4199841 TI - [Use of diamphenethide (Coriban) in sheep naturally invaded by Fasciola hepatica]. PMID- 4199842 TI - [Bactericidal effect of Lastanox Q]. PMID- 4199843 TI - [Various phenomena accompanying lethal shock due to bacillus cereus]. PMID- 4199844 TI - [Technics in the determination of economic effectiveness of the veterinary service in cases of porcineviral gastroenteritis]. PMID- 4199845 TI - Intrahepatic localisation of Australia antigen by fluorescent antibody technique. PMID- 4199846 TI - Quantitative studies of Australia antigen in acute and chronic hepatitis. Evidence for an inverse relationship between circulating Au-antigen and transaminase values in patients with progression from acute to chronic hepatitis. PMID- 4199847 TI - WHO Expert Committee on Biological Standardization: twenty-fifth report. PMID- 4199848 TI - [Premature rupture of amnion and ascending infection of amnion fluid. Experimental study]. PMID- 4199849 TI - [Osler's disease, pulmonary arterio-venous aneurysms and neurofibromatosis--a rare inherited disease combinations]. PMID- 4199850 TI - Ultrastructural study on contractile structures in mammalian nephron. Their development in the metanephros of human embryo. PMID- 4199851 TI - Ultrastructural studies of spermatogenesis in Drosophila melanogaster Meigen. PMID- 4199852 TI - [Effect o indomethacine on the increase of capillary permeability induced by various phlogistic substances]. PMID- 4199853 TI - Cholinesterase-containing nerve fibres on blood vessels in lungs of some laboratory mammals. PMID- 4199854 TI - Regulation of tRNA. PMID- 4199855 TI - Factors affecting the zinc content of E. coli alkaline phosphatase. PMID- 4199856 TI - Partial purification and properties of a nucleoside hydrolase from Crithidia. PMID- 4199857 TI - Activation of glutaraldehyde-crosslinked chymotrypsinogen-A. Enzymatic activity and circular dichroism studies. PMID- 4199858 TI - Purification and properties of enolase from swine kidney. PMID- 4199860 TI - [Controlled study of the action of maintenance therapy between attacks of duodenal ulcer]. PMID- 4199859 TI - Triosephosphate isomerases and aldolases from light- and dark-grown Euglena gracilis. PMID- 4199861 TI - Immunoglobulins of colostrum. I. Preparation and identification of ovine colostral immunoglobulins. PMID- 4199862 TI - Immunization of animals with Australia antigen. PMID- 4199863 TI - Possible linkage relationships between certain blood groups and schizophrenia or other psychoses. PMID- 4199864 TI - Effects of genetic variation and culture conditions on the social behavior of Drosophila melanogaster. PMID- 4199865 TI - The distribution and induction of some drug-metabolizing enzymes in man. PMID- 4199866 TI - Prostaglandin synthesis by the pregnant rat uterus at term and its possible relevance in parturition. PMID- 4199867 TI - Further experiments to establish that the analgesic action of aspirin-like drugs depends on the inhibition of prostaglandin biosynthesis. PMID- 4199868 TI - Effects of indomethacin on rat gastric acid secretion and mucosal blood flow. PMID- 4199869 TI - [Paraosteoarthropathies]. PMID- 4199870 TI - [Observation of various simple reflexes during the first 2 years of life in children after exsanguination and in children delivered by means of vacuum extraction]. PMID- 4199871 TI - [Subcapsular hepatic hematoma of the newborn infant and epilepsy in the mother]. PMID- 4199873 TI - Platelet diphenoloxidases in progressive muscular dystrophy (P.M.D.). PMID- 4199872 TI - [Treatment of major digestive fistulae by venous feeding]. PMID- 4199874 TI - Androgen-induced social dominance in infant female rhesus monkeys. PMID- 4199875 TI - [Experimental studies on absorption, excretion, distribution and metabolism of 3',4' dideoxykanamycin B. 1. Absorption, excretion, distribution and metabolism in rats]. PMID- 4199876 TI - [Pathophysiology of PCB poisoning]. PMID- 4199877 TI - [Air pollution and the lung]. PMID- 4199878 TI - [Evaluation of stimulation conditions in intraocular transfer]. PMID- 4199879 TI - [Incidence of ABO blood groups and D trait of the Rh system in patients with leukemia]. PMID- 4199880 TI - The general practitioner and the Oncology Organization. PMID- 4199881 TI - Care of the neurogenic bladder. PMID- 4199882 TI - [Radiological examination of the duodenum]. PMID- 4199883 TI - [Non-ulcerous diseases of the duodenum]. PMID- 4199884 TI - [Dental anomalies in monkeys of the Old World (Catarrhina)]. PMID- 4199885 TI - [Sodium cromoglycate and skin tests]. PMID- 4199886 TI - Sarcocysts in the heart muscle of a foal. PMID- 4199887 TI - Advances in methods of fertility regulation: report of a WHO scientific group. PMID- 4199888 TI - Use of disodium cromoglycate during the course of specific desensitizing treatment in asthmatic patients. PMID- 4199889 TI - Physiological gradients in development. A possible role for messenger ribonucleoprotein. PMID- 4199890 TI - [Detection of Australia antigen and the corresponding antibodies in blood donors in Antwerp]. PMID- 4199892 TI - Light-scattering effects on the circular dichroism of chloroplasts. PMID- 4199891 TI - Reaction of bovine and ovine pituitary growth hormones with tetranitromethane. PMID- 4199893 TI - Growth, isolation, and characterization of a yeast manganese alcohol dehydrogenase. PMID- 4199894 TI - Relationships among enzymes of the beta-ketoadipate pathway. I. Properties of cis,cis-muconate-lactonizing enzyme and muconolactone isomerase from Pseudomonas putida. PMID- 4199895 TI - Relationships among enzymes of the beta-ketoadipate pathway. II. Properties of crystalline beta-carboxy-cis,cis-muconate-lactonizing enzyme from Pseudomonas putida. PMID- 4199896 TI - Relationships among enzymes of the beta-ketoadipate pathway. 3. Properties of crystalline gamma-carboxymuconolactone decarboxylase from Pseudomonas putida. PMID- 4199897 TI - Specialized paranodal and interparanodal glial-axonal junctions in the peripheral and central nervous system: a freeze-etching study. PMID- 4199899 TI - [Problem of extrapolating toxicological data from laboratory animals to man]. PMID- 4199898 TI - Alterations of spatio-tactile discrimination after lesions of primate spinal cord. PMID- 4199900 TI - Evidence for LH and FSH binding protein(s) in human and rat serum. PMID- 4199901 TI - Effects of testosterone oenanthate on plasma concentrations of thyroxine, cortisol, testosterone and hormone binding proteins in patients with hypogonadism. PMID- 4199902 TI - Reduced plasma thyrotropin response to thyrotropin releasing hormone after dexamethasone administration in normal subjects. PMID- 4199903 TI - Glucose, FFA, IRI and GH response to I.V. glibenclamide. PMID- 4199904 TI - Adverse reactions of antirheumatic drugs. PMID- 4199905 TI - [Possible causes of drug induced side effects in elderly people]. PMID- 4199906 TI - Differences in access into the central nervous system of ME7 scrapie agent from two strains of mice. PMID- 4199907 TI - Scrapie in mice. Some effects on the brain lesion profile of ME7 agent due to genotype of donor, route of injection and genotype of recipient. PMID- 4199909 TI - Non-specific agglutination of Mycoplasma gallisepticum by rheumatoid factor-like antiglobulin in chickens infected with Streptococcus faecalis or Staphylococcus aureus. PMID- 4199908 TI - Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation. PMID- 4199910 TI - Levels of IgM and IgG in the sera of normal and leukaemic calves. PMID- 4199911 TI - Further evidence of plasma membrane material in skim milk. PMID- 4199912 TI - [The usefulness of TRF (thyrotropin releasing factor) test in patients with hypothalamic-pituitary disorders]. PMID- 4199914 TI - Blood parasites of Pekin Robins (Liothrix luteus). PMID- 4199913 TI - Experimental brain death. I. Morphology and fine structure of the brain. AB - The morphological characteristics of brain death were examined in baboons and cats after artificial cerebral ischaemia. All animals showed autolytic changes in the brain, ischaemic neuronal changes, midbrain haemorrhages, focal necrosis of the brain-stem, demarcation at C 1/C 2 cord segment, and displacement of cerebellar tissue. Ultrastructural examination revealed extreme brain oedema, autolytic changes, and complete obstruction of capillaries by astrocytic and endothelial swelling and intravascular blebs. These data indicate that brain death develops in several stages. If the process starts in the supratentorial space it first leads to a breakdown of the cerebral circulation and to transtentorial herniation. As a result, midbrain haemorrhages develop and the infratentorial pressure begins to rise. The second stage is terminated by demarcation of the brain. The circulatory arrest is initially caused by venous compression but becomes irreversible when vascular obstruction develops. PMID- 4199915 TI - Zschokkella floridanae sp. n. (Myxosporidea) from the goldspotted killifish, Floridichthys carpio (Gunther). PMID- 4199916 TI - Effects of glutaraldehyde and osmium tetroxide on hypotrichous ciliates, and determination of the most satisfactory fixation methods for electron microscopy. PMID- 4199917 TI - Haematozoa in domestic chickens and guinea fowl in Tanzania and transmission of Leucocytozoon neavei and Leucocytozoon schoutedeni. PMID- 4199918 TI - The polychlorinated biphenyls Aroclors 1248 and 1260: effect on and accumulation by Tetrahymena pyriformis. PMID- 4199919 TI - Hydroxyproline in Tetrahymena. PMID- 4199920 TI - Variation in glyoxylate bypass inducibility among strains of Tetrahymena pyriformis. PMID- 4199921 TI - The prognosis following surgical removal of mastocytomas in dogs. PMID- 4199922 TI - Biodegradation of oleates. PMID- 4199923 TI - [Activity of certain blood serum enzymes in patients operated on the biliary tract]. PMID- 4199924 TI - [Evaluation of the results of postoperative cholangiomanometry through drainage]. PMID- 4199925 TI - Thiazides and hypokalaemia in diabetic ketoacidosis. PMID- 4199926 TI - Occlusion of the posterior ciliary arteries. PMID- 4199927 TI - [Comparative evaluation of elective media for isolating Listeria]. PMID- 4199928 TI - [Interaction of the listeriosis phage with the host cell]. PMID- 4199929 TI - [Oxidative metabolism in various strains of Listeria monocytogenes]. PMID- 4199930 TI - [Role of ticks in the spread of poultry paratyphoid]. PMID- 4199932 TI - Studies on Fes, a mutation affecting cystocyte cytokinesis, in Drosophilia melanogaster. PMID- 4199931 TI - Relative safety of self inflicted overdose with relatively newer medications. PMID- 4199933 TI - Aggregation of horseshoe crab (Limulus polyphemus) amebocytes and reversible inhibition of aggregation by EDTA. PMID- 4199934 TI - [Incidence of so-called free blood cells in pregnant women]. PMID- 4199935 TI - [Differentiation of hypothalamic sex in subhuman primates and in man]. PMID- 4199936 TI - The effects of inhibition of protein synthesis on the phenotype of Abnormal abdomen. PMID- 4199937 TI - Multiple gene control of the tRNA aminoacylating system in Drosophila melanogaster. PMID- 4199938 TI - A new sex factor of Pseudomonas aeruginosa. PMID- 4199939 TI - Isolation of a transducing phage forming plaques on Pseudomonas maltophilia and Pseudomonas aeruginosa. PMID- 4199940 TI - [Paroxysmal nocturnal hemoglobinuria]. PMID- 4199941 TI - [Transitory recurrent granulocytopenia induced by hemodialysis]. PMID- 4199942 TI - [Erythropoiesis and myelopoiesis in congenital athyroidism]. PMID- 4199943 TI - [Hereditary spherocytosis in the Manluan Trans-Po area. Clinical and hematological aspects]. PMID- 4199944 TI - [Pure erythroblastopenia associated with thymoma. Complete remission after immunodepressive therapy]. PMID- 4199945 TI - [Clinical and cytogenetic aspects in 3 cases of childhood erythroleukemia]. PMID- 4199946 TI - [Splenectomy in chronic lymphoid leukemia. A clinical case]. PMID- 4199947 TI - [Immuno-pathological aspects of rheumatoid arthritis]. PMID- 4199948 TI - [The role of phototherapy in the treatment of fetal erythroblastosis]. PMID- 4199950 TI - Possible human-animal paranormal events. PMID- 4199949 TI - [Evaluation of the erythropoiesis in newborn infants by means of autoradiography, cytospectrophotometry and short term bone marrow cultures]. PMID- 4199951 TI - Benthic marine and blue-green algal species as a source of choline. PMID- 4199952 TI - [Clinical application of electrophoresis. 8. Glycoprotein]. PMID- 4199953 TI - [Ampicillin and doxacillin in fixed combination for the antibiotic therapy in pediatrics]. PMID- 4199954 TI - [Isolation and study of the DNA from the protoplasts of Plectonema boryanum]. PMID- 4199956 TI - [Action of protionamide on tuberculosis mycobacteria in vitro]. PMID- 4199955 TI - [Electron microscopic study of the DNA of the virus of Plectonema boryanum]. PMID- 4199957 TI - [Combined action of tetracyclines with erythromycin on Rickettsia prowazekii]. PMID- 4199958 TI - Simultaneous bilateral focal seizures without loss of consciousness. PMID- 4199960 TI - The utilization of bacteria as food for Paramecium bursaria. PMID- 4199959 TI - A neural system analysis of memory storage and retrieval. PMID- 4199961 TI - [Esophageal diverticulosis as a cause of recurrent hemorrhages]. PMID- 4199962 TI - Intraluminal duodenal diverticulum in a child. PMID- 4199963 TI - [Results of polychemotherapy in neoplasms of the lymphoreticular system]. PMID- 4199964 TI - [Long-term treatment of arterial occlusive diseases using vasodilator agents]. PMID- 4199965 TI - [Long-term drug therapy of chronic arterial occlusive diseases]. PMID- 4199966 TI - [Quality of home therapy as illustrated on the example of long-term therapy with cardiac glycosides and anticoagulants]. PMID- 4199967 TI - [Results and limitations of long-term therapy in diabetes mellitus]. PMID- 4199968 TI - [Characteristics of the higher nervous activity of simians in the post-neurotic period]. PMID- 4199969 TI - [Successive differentiation of visual stimuli under different conditions of presentation in apes]. PMID- 4199970 TI - Plasma epinephrine and plasma norepinephrine concentrations in early diabetes. PMID- 4199971 TI - The drosopterin pattern in various eye color mutants of the fruitfly. Drosophila melanogaster. PMID- 4199972 TI - Maternal effects on x-ray-induced sex chromosome loss in mature sperm of Drosophila melanogaster: a storage effect in mature oocytes. PMID- 4199973 TI - [Prinzmetal's angina. Apropos of 16 selective coronary cineangiographies and 13 operations (aortocoronary bypass)]. PMID- 4199975 TI - [Prinzmetal's angina; coronarographic aspects; therapeutic considerations. Apropos of 7 cases]. PMID- 4199974 TI - [Prinzmetal's angina: contribution of coronarography and discussion on surgery of revascularization (apropos of 13 cases including 10 selective coronarographies and 9 aortocoronary bypasses)]. PMID- 4199976 TI - [Radioisotopic coronary blood flow and coronarography]. PMID- 4199977 TI - [Surgical treatment of chronic coronary insufficiency. Apropos of a series of 150 cases (study of middle-term results)]. PMID- 4199978 TI - [Correlation of clinical, hemodynamic and biological data at the acute stage of myocardial infarction]. PMID- 4199979 TI - [Mechanisms of arterial hypoxemia at the acute stage of myocardial infarction]. PMID- 4199980 TI - [Type A Wolff-Parkinson-White syndromes, inapparent or latent in sinus rhythm]. PMID- 4199981 TI - [Value of skin biopsy in coronary insufficiency]. PMID- 4199983 TI - [Cardiovascular system in progressive muscular dystrophy]. PMID- 4199982 TI - [Treatment of coronary thrombosis with streptokinase]. PMID- 4199984 TI - [Right heart catheterization with a Swan Ganz probe]. PMID- 4199985 TI - Dominance measurements of low and high protein reared rhesus macaques. PMID- 4199986 TI - On the specificity of Pseudomonas aeruginosa alkaline proteinase with synthetic peptides. PMID- 4199987 TI - Size heterogeneity of human IgA myeloma proteins. Relationships between polymers and "J" chain. PMID- 4199988 TI - Selective activation of T lymphocytes. Its possible application in the immunomanipulation of tumours. PMID- 4199991 TI - [The Great poem leads the way. Yukiang's flag is now redder than ever: how the Yukiang people have achieved eradication of schistosomiasis]. PMID- 4199990 TI - [Simple juvenile goiter and blood thyrotropin (TSH) levels. Effects of the thyrotropin releasing factor (TRH)]. PMID- 4199992 TI - [Remember firmly Chairman Mao's teachings, fight for a greater achievement]. PMID- 4199993 TI - [Experimental studies on the treatment of schistosomiasis japonica with oral F30066 and rectal dipterex]. PMID- 4199994 TI - [Histochemical method for stage-differentiation of Schistosoma japonicum ova in biopsy materials]. PMID- 4199995 TI - [Clinicopathological and experimental studies of myohemoglobinuric nephrosis]. PMID- 4199996 TI - [Severe diabetic ketoacidosis coma and hyperosmolar coma]. PMID- 4199997 TI - [Ultrasound in the diagnosis of pericardial effusion]. PMID- 4199998 TI - [Syndrome of the lateral portion of the medulla oblongata: clinicopathologic report of 2 cases]. PMID- 4199999 TI - [Studies on the chemical constituents of Scutellaria baicalensis]. PMID- 4200000 TI - [Experimental study on mechanical dilation of blood vessels]. PMID- 4200001 TI - [New method in the treatment of anterior urethral stricture: bouginage with an indwelling plastic urethral dilator]. PMID- 4200002 TI - [X-ray diagnosis of tumors in deep soft tissues of the chest wall]. PMID- 4200003 TI - [Electrical resistance of rabbit pinna in experimental peritonitis]. PMID- 4200004 TI - [Clinicopathological conference. 5. Vomiting, spasm and syncope]. PMID- 4200005 TI - [Porcine cyclops]. PMID- 4200006 TI - [Partial trisomy 10 due to hereditary translocation t(1;10)(q44;q22)]. PMID- 4200007 TI - East Coast fever: the infectivity for cattle of infective particles of Theileria parva harvested in various substrates. PMID- 4200008 TI - Babesia argentina: intraerythrocytic location of babesial antigen extracted from parasite suspensions. PMID- 4200010 TI - The responses to various stimuli of microfilariae of Dirofilaria corynodes, of Dipetalonema marmosetae and of unidentified species of filariae in Saimiri sciureus and Cacajao monkeys. PMID- 4200009 TI - Characterization of a glycoprotein in the cyst fluid of Cysticercus tenuicollis from the goat. PMID- 4200012 TI - Measuring health care. PMID- 4200011 TI - Isolation of blood-stage merozoites from Plasmodium knowlesi malaria. PMID- 4200014 TI - Gastric pseudoadenomyosis in a Macaca mulatta. PMID- 4200013 TI - The establishment and maintenance of a small, inexpensive baboon colony for behavioral research. PMID- 4200015 TI - Progesterone levels in the Sooty mangabey (Cercocebus atys) during the menstrual cycle, pregnancy and parturition. PMID- 4200017 TI - Convenient sites for venipuncture in smaller primates. PMID- 4200016 TI - Aortic intimal lesions and serum lipids in wild baboons. PMID- 4200018 TI - Precursors of 5 S ribosomal RNA in Bacillus subtilis. PMID- 4200019 TI - Whole-body retention of 65Zn after single and daily oral administration in young and adult mice. PMID- 4200020 TI - [Studies on the filament forms of Pseudomonas aeruginosa by cinematography]. PMID- 4200021 TI - [Case of trilobed duodenal diverticula]. PMID- 4200022 TI - [Ultra structure of pigmented nevus cells and intracellular distribution of Dopa oxidase]. PMID- 4200023 TI - The critical concentration of clinical rifampicin resistance for tubercle bacilli and the acquirement pattern of rifampicin resistance of tubercle bacilli on Kirchner's semi-liquid agar media. PMID- 4200027 TI - Psychiatric and psychological research in the Navy before World War II. PMID- 4200028 TI - An alternative method of flap reflection for mandibular third molars. PMID- 4200029 TI - Acinic cell adenocarcinoma of minor salivary gland origin. PMID- 4200032 TI - Optometry: ophthalmology's obligation. PMID- 4200033 TI - [Polisography conducted by chromatoroentgenographic technique (studies on chromatoroentgenography, second report)]. PMID- 4200034 TI - Serum triiodothyronine, total thyroxine, and thyroxine to triiodothyronine ratios in paired maternal-cord sera and at one week and one month of age. PMID- 4200035 TI - [Diagnostic evaluation of dysphagia. II. Zenker's (pulsion) diverticulum coexisting with an ulcer-like neoplastic type niche of the upper medial 3d, vertical portion, of the gastric lesser curvature]. PMID- 4200036 TI - [Change of anti-Aspergillus fumigatus serum precipitins during treatment of pulmonary aspergillosis. Apropos of 35 cases]. PMID- 4200037 TI - [Immunochemical diagnosis of dysproteinemia]. PMID- 4200038 TI - Corneal pathogenicity of Serratia marcescens in the rabbit. PMID- 4200039 TI - [Use of radioactive isotopes in resistance determination of mycobacteria]. PMID- 4200041 TI - Electromyography of the oral phase of deglutition in the Rhesus monkey (Macaca mulatta). PMID- 4200040 TI - Growth inhibition by L-phenylalanine in Agmenellum quadruplicatum. A clue to some amino acid interrelationships. PMID- 4200042 TI - Metabolism and function of polyisoprenol sugar intermediates in membrane associated reactions. PMID- 4200043 TI - Effect of prostaglandins on oviduct motility in estrous rabbits. PMID- 4200044 TI - [The use of Ilex chinensis Sims in the treatment of burns]. PMID- 4200045 TI - [Structure and function of releasing factors]. PMID- 4200046 TI - [Clinical cases with interesting responses in TRF tests]. PMID- 4200047 TI - [Stimulation of glucose oxidation and phospholipid synthesis in the pituitary gland by TRH]. PMID- 4200048 TI - [High energy therapy of salivary gland tumors (cobalt teletherapy, betatron therapy)]. PMID- 4200049 TI - The effects of ethanol on the liver. PMID- 4200050 TI - Immunochemical studies on cobrotoxin. PMID- 4200051 TI - Production of anti-idiotypic and anti-class specific antibody using micro amounds of myeloma serum. PMID- 4200052 TI - [Epidemiological observation of rubella by survey on the sera of pregnant women in Kawasaki]. PMID- 4200053 TI - [Frequency of rubella HI antibody among individuals in Iriomote island in 1970]. PMID- 4200054 TI - [Systemic and local effects of corticosteroids on the experimental intradermal pneumococcal infections in rabbits]. PMID- 4200055 TI - [Epidemiological significance of antibodies to group A streptococcal T antigen in human serum]. PMID- 4200056 TI - Improved methods of non-oral neonatal feeding: a commentary. PMID- 4200057 TI - [Studies on the development of drug-resistant tubercle bacilli in experimental animal tuberculosis]. PMID- 4200058 TI - [The relation between bacilli negative conversion rate and the number of combined sensitive antituberculous drugs in intermittent administration of rifampicin for severe pulmonary tuberculosis]. PMID- 4200059 TI - Research on dengue in tissue culture. V. Production of anti-dengue antibodies in tissue cultures from monkeys inoculated with an attenuated type I dengue virus strain. PMID- 4200061 TI - Effect of synthetic thyrotropin-releasing factor (TRF) on pituitary TSH secretion in man, with special reference to the evaluation for TRF test. PMID- 4200060 TI - Pathogenesis and immunity of dengue infection in man. PMID- 4200062 TI - If your patient can't tolerate the cold--suspect cryoglobulinemia. PMID- 4200063 TI - [Hemorrhagic diathesis in calves as a result of continuous furazolidone feeding]. PMID- 4200064 TI - [Comparison of Salmonella findings in meat and man in Vienna in 1972]. PMID- 4200065 TI - [Observations on the incidence of dietetic microangiopathies ("mulberry heart") in swine in northeastern Lower Austria]. PMID- 4200067 TI - [Neurotherapeutic effect of procaine injections on the bovine thyroid gland]. PMID- 4200066 TI - [Duration of pregnancy, parturition and birth weight as well as growth in Piedmontese-Prinzgau cattle crosses]. PMID- 4200068 TI - [Guidelines for the evaluation of mastitis drugs]. PMID- 4200070 TI - ["Highest permissible doses" in international and Austrian radiation protection regulations]. PMID- 4200069 TI - [Guidelines for the evaluation of chemical disinfectants used for the control of mastitis]. PMID- 4200071 TI - Federal Medical Chiefs on progress and plans: Department of Defense. PMID- 4200073 TI - Federal Medical Chiefs on progress and plans: Army Medical Department. PMID- 4200072 TI - Federal Medical Chiefs on progress and plans: Department of Health, Education, and Welfare. PMID- 4200074 TI - Federal Medical Chiefs on progress and plans: Navy Medical Department. PMID- 4200075 TI - Federal Medical Chiefs on progress and plans: Air Force Medical Services. PMID- 4200076 TI - Federal Medical Chiefs on progress and plans: Veterans Administration. PMID- 4200077 TI - Experience with mixed infections of Plasmodium falciparum and vivax. PMID- 4200078 TI - Preliminary report: comprehensive screening and education for sickle cell anemia. PMID- 4200079 TI - Phencyclidine induced psychosis. The need to avoid unnecessary sensory influx. PMID- 4200080 TI - Low-cost system of dispensing solutions to parallel-flow dialyzers. PMID- 4200081 TI - Case for diagnosis. PMID- 4200082 TI - Prolongation of active useful life. PMID- 4200083 TI - [Current trends in the therapy of bronchial asthma in infancy (excluding acute attacks) and short notes on its pathogenesis]. PMID- 4200084 TI - Maternal dietary supplementation and infant birth weight. PMID- 4200085 TI - Discrimination learning without reward. PMID- 4200086 TI - [Septic shock and the pulmonary lesion]. PMID- 4200087 TI - [Immunity against Trypanosoma cruzi induced by ribonucleic acid]. PMID- 4200088 TI - WHO expert committee on drug dependence. Nineteenth report. PMID- 4200089 TI - Chemotherapy of malaria and resistance to antimalarials. Report of a WHO scientific group. PMID- 4200090 TI - [Immunopathology of multiple sclerosis: relationship between the development of the disease and serum and cerebrospinal fluid C1-3 levels]. PMID- 4200091 TI - Observations following high intensity white light exposure to the retina. PMID- 4200092 TI - Limits for single cell protein utilization in human feeding. PMID- 4200093 TI - Abrasion of composite restorative material. PMID- 4200094 TI - An evaluation of nitrous oxide oxygen analgesia after two years of use. PMID- 4200095 TI - Prescribing supplemental fluorine in fluoride deficient water suppliers. PMID- 4200096 TI - Isozyme variability in species of the genus Drosophila. VI. Frequency-property environment relationships of allelic alcohol dehydrogenases in D. melanogaster. PMID- 4200097 TI - A novel hypoglycemic compound. PMID- 4200098 TI - The basis for progress in chemotherapy. PMID- 4200099 TI - Cancer chemotherapeutic agents. PMID- 4200100 TI - L-asparaginase for the treatment of cancer. PMID- 4200101 TI - Chemotherapy of skin cancer. PMID- 4200103 TI - [Level and perspectives of health protection and the integration of surgery]. PMID- 4200102 TI - A chemotherapy-radiotherapy Rx regimen for children with stage 3 Hodgkin's disease. PMID- 4200104 TI - A personal tribute to Sidney Farber, M.D. (1903-1973). PMID- 4200105 TI - [A method for measuring the heart rate while diving]. PMID- 4200106 TI - [Diseases and functional disorders of the respiratory tract in workmen of the wood processing industry]. PMID- 4200107 TI - [Extended studies on the diagnosis of farmer's lung]. PMID- 4200108 TI - [Gravimetric measurements of the dust while sanding exotic plywoods]. PMID- 4200109 TI - [Significance of hypotheses in the demographic prognosis]. PMID- 4200110 TI - [Oxytocin]. PMID- 4200111 TI - [Thyrotropin releasing factor (TRF) test: standardization of pituitary TSH secretion potential test and results in various endocrine diseases]. PMID- 4200112 TI - [Hyperthyroidism with unusual thyroid stimulator detected in the pituitary gland]. PMID- 4200113 TI - [Determination of thyroxine binding globulin capacity with cellulose acetate electrophoresis]. PMID- 4200114 TI - Chronic recurrent pancreatitis and pancreatic pseudocysts. PMID- 4200115 TI - Effects of progesterone on the ocular hypertensive response to prostaglandin. PMID- 4200116 TI - Detection of small amounts of pesticides in human biological material by thin layer chromatography. PMID- 4200117 TI - [Abnormal hemoglobins and elevation of A2 hemoglobin and erythrocyte carbonic anhydrase isoenzymes in a hospital population of Puebla]. PMID- 4200119 TI - The purification of human polyclonal IgE by immunosorption. PMID- 4200118 TI - Protein A from Staphylococcus aureus. XVI. Alkylation with iodoacetic acid at different pH-values. PMID- 4200120 TI - Quantitative studies on the interaction of concanavalin A, the carbohydrate binding protein of the jack bean, with model carbohydrate-protein conjugates. PMID- 4200121 TI - Active sites of turtle and duck low molecular weight antibody to 2'4'dinitrophenol. PMID- 4200122 TI - J chain in pig immunoglobulins. PMID- 4200123 TI - Early interactions between inhibitors and antibodies to lysozyme. PMID- 4200124 TI - Equine anti-hapten antibody. VII. Anti-lactoside antibody induced by a bacterial vaccine. PMID- 4200125 TI - Rabbit -fetoprotein: immunochemical purification and partial characterization. PMID- 4200126 TI - Immunochemical analysis of rat brain microsomes. PMID- 4200127 TI - Detection of the e14 and e15 rabbit allotypic specificities by immunodiffusion in PEG agar. PMID- 4200129 TI - A mathematical model for the determination of viscoelastic behavior of brain in vivo. I. Oscillatory response. PMID- 4200128 TI - Effect of cycloheximide on L-leucine transport by Penicillium chrysogenum: involvement of calcium. AB - Cycloheximide (actidione) has an immediate inhibitory effect on amino acid transport by nitrogen-starved or carbon-starved mycelium suspended in phosphate buffer. High concentrations of phosphate alone are slightly inhibitory; cycloheximide appears to potentiate the effect of phosphate. Ca(2+) reverses the inhibition of transport caused by phosphate plus cycloheximide. Ca(2+) did not relieve the inhibition of protein synthesis. Cycloheximide promotes a continual uptake of (45)Ca(2+) by the mycelium. The cumulative results suggest that (i) membrane-bound Ca(2+) is involved in amino acid transport, (ii) cycloheximide labilizes the membrane-bound Ca(2+), and (iii) phosphate forms a complex with Ca(2+) making it unavailable for its role in transport. The effect of cycloheximide described above is observed within 1 to 2 min after addition of the antibiotic. This initial inhibition occurs more rapidly with 10(-3) M cycloheximide than with 10(-5) M cycloheximide. However, after a longer preincubation time, a curious inverse relationship between cycloheximide concentration and amino acid transport is observed. The mycelium incubated with 10(-5) M cycloheximide remains strongly inhibited (unless the antibiotic is washed away). The mycelium incubated with 10(-3) M cycloheximide recovers about 40% of the transport activity lost during the rapid initial phase. We have no obvious explanation for the inverse effect. PMID- 4200130 TI - The fracture characteristic of bone substance. PMID- 4200131 TI - Movement and metabolism of phorate under field conditions after granular band applications. PMID- 4200132 TI - Effects of physical and chemical agents on competing- and transforming-abilities of DNA in Bacillus subtilis. PMID- 4200133 TI - Isolation of infectious bursal disease virus and distribution of precipitating antibodies in chicken sera. PMID- 4200134 TI - [Antituberculous activities of the tuberactinomycins in vitro and in experimental animals]. PMID- 4200136 TI - Controlled evaluation of flurazepam hydrochloride, a new nonbarbiturate hypnotic. PMID- 4200135 TI - [Results of radiotherapy of malignant neoplasms with fractionated doses]. PMID- 4200137 TI - The current status of HAA testing at Brooke Army Medical Center. A review of two years' experience. PMID- 4200138 TI - Case for diagnosis. PMID- 4200140 TI - A study of communications between Walter Reed Army Medical Center and surrounding mental health units. PMID- 4200139 TI - Synchronized versus nonsynchronized electrocardioversion. PMID- 4200141 TI - The relationship of mid-face fractures to mandibular fractures in various forms of trauma: study of 4,015 cases. PMID- 4200142 TI - The treatment of closed head injury. PMID- 4200143 TI - Volkmann's ischemia treated by transfibular fasciotomy. PMID- 4200144 TI - Vasopressin-resistant diabetes insipidus associated with short-term demethylchlortetracycline (declomycin) therapy. PMID- 4200145 TI - Some challenges for military medicine in the next decade. PMID- 4200146 TI - Closed injuries of the ankle. PMID- 4200147 TI - [Use of gelatinol for preparing standard anti-Rh serum]. PMID- 4200148 TI - [Simian malaria in the state of Goias, Brazil: findings of Alouatta caraya monkeys infected with Plasmodium brazillianum]. PMID- 4200149 TI - [New simian hosts of Plasmodium brasilianum in the State of Acre, Brazil: the ouacari Cacajo rubicundus rubicundus, the howling monkey Allouatta seniculus seniculus and the wooly-monkey Lagothrix lagotricha poeppigii]. PMID- 4200150 TI - Species and stage interaction in the feeding behaviour of vectors of Chagas disease (the importance of determinants in planning for greater efficacy and standardization of xenodiagnostic procedures). PMID- 4200151 TI - [What does it cost to treat a diabetic child?]. PMID- 4200152 TI - [Immunoglobulins in obstructive jaundice]. PMID- 4200153 TI - [Therapy of rhinopathia allergica (pollinosa) using disodium cromoglycate]. PMID- 4200154 TI - [Therapy of liver diseases using Silymarin (Legalon)]. PMID- 4200155 TI - Hormonal changes in pathological pregnancy. PMID- 4200156 TI - [Sensitivity of T. vaginalis Donne and other vaginal microorganisms to Macmiror in vitro]. PMID- 4200157 TI - [Dysbiosis-treatment]. PMID- 4200158 TI - Inhibitory effect of antibiotic Wr-142 on synthesis of nucleic acids and proteins in B. subtilis cells. PMID- 4200159 TI - [Trisomy 18 and esophageal diverticulum]. PMID- 4200160 TI - [Chemical carcinogenesis and tumors of the central nervous system]. PMID- 4200161 TI - The effect of chloramphenicol on the production of cyanophycin granule polypeptide in the blue green alga Anabaena cylindrica. PMID- 4200162 TI - Enzymatic characterization of a phenylalanine auxotroph of the blue-green bacterium Synechococcus cedrorum. PMID- 4200164 TI - Human glomerular basement membrane. Selective solubilization with chaotropes and chemical and immunologic characterization of its components. PMID- 4200165 TI - Characterization of monkey pox virus DNA genome. PMID- 4200166 TI - [Neoblasts of the planarian Dendrocoelum lacteum: ultrastructure, morphologic evolution after section and study of RNA synthesis in cases of cephalic regeneration and non-regeneration]. PMID- 4200167 TI - [Blocking of cell division and malformations induced by vitamin B 12 deficiency in synchronic cells of Euglena gracilis Z]. PMID- 4200169 TI - [Action of Pseudomonas aeruginosa lysins on bacterial membranes]. PMID- 4200168 TI - [Interfertility in the genus Lumbricus. Cross fecundation between worms belonging to the same species (terrestris) but living in different biotopes and between worms of different species (rubellus and terrestris) living in the same biotope]. PMID- 4200170 TI - [Relation between resistance to antibiotics and serotype in Pseudomonas aeruginosa]. PMID- 4200163 TI - Early events in cell-animal virus interactions. PMID- 4200171 TI - [Effect of indomethacin on the increase of capillary permeability induced by various phlogistic substances]. PMID- 4200172 TI - [Immunological examination in hematology and transfusion service. Regarding the article of Assistant Prof. J. Strejcek, C.Sc.: "clinical immunology in medical practice"]. PMID- 4200173 TI - Development and application of a rapid cell sorter. PMID- 4200174 TI - Quantitation of serum lipids by a simple TLC-charring method. PMID- 4200175 TI - The immunoassay of thyroid-stimulating hormone and its clinical applications. PMID- 4200176 TI - Purification and molecular properties of an unspecific carboxylesterase (E1) from rat-liver microsomes. PMID- 4200177 TI - Association-dissociation behaviour and hydrodynamic properties of apoferritin monomer and dimer. PMID- 4200178 TI - The synthesis and stability of ribosomal RNA in blue-green algae. PMID- 4200179 TI - Isolation of high-molecular-weight DNA from mammalian cells. PMID- 4200180 TI - Isolation and characterization of cytoplasmic L-glycerol-3-phosphate dehydrogenase from rabbit-renal-adipose tissue and its comparison with the skeletal-muscle enzyme. PMID- 4200181 TI - [Etiology of plasmacellular interstitial pulmonitis]. PMID- 4200182 TI - [Certain aspects of Pneumocystis carinii from patients who died from interstitial plasmacellular pulmonitis]. PMID- 4200184 TI - [Variations in serum immunoglobulins during specific hyposensitization]. PMID- 4200183 TI - [The isoelectric point of extracellular proteases of certain bacterial species]. PMID- 4200185 TI - Resorption of amyloid and enzymatic studies in amyloidosis. PMID- 4200186 TI - Treatment of multirooted teeth with internal root resorption and perforation. Case history. PMID- 4200187 TI - How to increase the utilization and efficiency of the office laboratory for fixed prosthesis. PMID- 4200189 TI - [What is professional medicine's position at present on the "Pill"?]. PMID- 4200188 TI - Studies on the adaptation of the toad Bufo viridis to high salinities: oxygen consumption, plasma concentration and water content of the tissues. PMID- 4200190 TI - [Fall in serum immunoglobulins: indication of malignant disease]. PMID- 4200191 TI - [Continuous slow enteral alimentation. Principles, methods, prospects (280 cases)]. PMID- 4200192 TI - [Heterogeneity of skeletal muscle glycogen synthetase]. PMID- 4200194 TI - [Rapid sensitive herbicide bioassay by inhibition of trichome-migration of bluegreen algae]. PMID- 4200193 TI - [Oral and nasal immunization with poxvirus vacciniae. IV. Studies of oral immunization in monkeys]. PMID- 4200195 TI - [Examinations of the effect of antibacterial prepared plastic foils]. PMID- 4200196 TI - Survival versus growth of a facultative psychrotroph meat and products of meat. PMID- 4200197 TI - [Lactate, pyruvate, glucose, and hydrogen ions in the venous blood of riding horses in various stages of training]. PMID- 4200198 TI - [Heart rate during standardised exercise as a measure for the working capacity of horses]. PMID- 4200199 TI - [Motion analysis in trotting horses using ungulography]. PMID- 4200200 TI - [Studies on the fatty liver problem in laying hens. 3. Effect of restrictive feeding on egg production and egg weight at the beginning of the laying period]. PMID- 4200201 TI - [Studies on the function of the fore-stomach in muridae. I. Passage of solid and fluid food parts, pH-value, and activity of alpha amylase in the fore-stomach of the rat]. PMID- 4200202 TI - [The "metastasising thyroid adenoma" (Wegelin) in ursidae]. PMID- 4200203 TI - The oviducts of the Egyptian cow in health and disease. PMID- 4200204 TI - Purulent pneumococcal pericarditis. A continuing problem in the antibiotic era. PMID- 4200205 TI - A primordial bifunctional polyglucan-forming enzyme. PMID- 4200206 TI - An assessment of the role of parenteral alimentation in the management of surgical patients. PMID- 4200207 TI - Effects of saline and colloid resuscitation on renal function. PMID- 4200208 TI - Serotonin and central nervous system function. PMID- 4200209 TI - [Glucagon in the acute stage of myocardial infarct]. PMID- 4200210 TI - [Comparison between the peripheral vascular action of dopamine, norepinephrine, and isopropylnoradrenaline. Experimental study]. PMID- 4200212 TI - [Hemolysis in patients with heart valve prosthesis]. PMID- 4200211 TI - [Surgical treatment of myocardial infarction with shock]. PMID- 4200213 TI - [Function tests in the diagnosis of aortic valve diseases]. PMID- 4200214 TI - [Long term results of aortic valve prosthesis]. PMID- 4200215 TI - [Long term results of heterogenous valves]. PMID- 4200216 TI - [Aortic valve replacement surgery apropos of 168 operations]. PMID- 4200217 TI - [Study of left ventricular function in aortic insufficiency and stenosis]. PMID- 4200218 TI - [Therapy of late gestational toxicosis using Briserin]. PMID- 4200219 TI - Congenital goiter in four euthyroid siblings with glandular and circulating iodoproteins and defective iodothyronine synthesis. PMID- 4200220 TI - Gene loci for the skin and their chromosomal positions. PMID- 4200221 TI - Antimicrobials. New nitrofuran derivatives. PMID- 4200222 TI - Preparation and biological activity of various 3-deazapyrimidines and related nucleosides. PMID- 4200223 TI - [Bacteriological studies on 3',4'-dideoxykanamycin B]. PMID- 4200224 TI - [The rational use of nitroglycerin in delayed-action form in angina pectoris]. PMID- 4200225 TI - Gonorrhoea. PMID- 4200226 TI - [Hypogonadotrophic hypogonadism in males. Discussion. Long-term therapeutic results]. PMID- 4200227 TI - [Hypogonadotrophinic hypogonadism in females. Treatment and long term results]. PMID- 4200228 TI - [Precocious puberty and tumors of the 3rd ventricle]. PMID- 4200229 TI - Aural tuberculosis in children. PMID- 4200230 TI - Biological basis for high-LET radiotherapy. PMID- 4200231 TI - [Examination of the TRH-TSH axis]. PMID- 4200233 TI - [Hiatal hernia in adults. General etiology]. PMID- 4200232 TI - [Functional exploration of the TRH-TSH thyroid axis. Tests of hypophyseal reserve]. PMID- 4200234 TI - [Treatment of intestinal infarct]. PMID- 4200235 TI - Absorption of edema following ankle fractures. PMID- 4200236 TI - Influence of heparin-plasma, EDTA-plasma, and serum on the determination of insulin with three different radioimmunoassays. PMID- 4200237 TI - Potential environmental chemical hazards. 3. Industrial and miscellaneous agents. PMID- 4200238 TI - [Localization and structural functional organization of the nuclear system of the vagus nerves comprising the (cardiac center) of the medulla oblongata]. PMID- 4200239 TI - [Problems associated with the administration of combined antibacterial drugs]. PMID- 4200240 TI - [Biochemical basis of parenteral feeding]. PMID- 4200242 TI - [Morphological-taxonomical studies on Paragonimus uterobilateralis (Trematoda, Troglotrematidae) as well as observations of the life cycle and the spread of the parasite in Liberia]. PMID- 4200241 TI - Serum immunoglobulin levels in five villages of the Republic of Chad and in onchocerciasis patients with and without microfilaruria. PMID- 4200243 TI - Suppression of Plasmodium falciparum malaria in Aotus monkeys by milk diet. PMID- 4200244 TI - [Immunologic studies on Trypanosoma cruzi, the causative agent of Chagas' disease]. PMID- 4200245 TI - Cell mediated immunity in mice innoculated with epimastigotes or trypomastigotes or Trypanosoma cruzi. PMID- 4200246 TI - [Oral and nasal immunization with Poxvirus vacciniae. 3. Animal experiments]. PMID- 4200247 TI - General mechanisms of regeneration as elucidated by experiments of planarians and by a new formulation of the morphogenetic field concept. PMID- 4200248 TI - An atypical immunoglobulin A in benign monoclonal gammopathy. PMID- 4200249 TI - Repair processes on deoxyribonucleic acid. PMID- 4200250 TI - Toxicological problems relating to changes in the environment. PMID- 4200251 TI - Molecular structure and biosynthesis of the fatty acid synthetase-multienzyme complex of yeast. PMID- 4200252 TI - [Rare combination of ocular and osseous abnormalities]. PMID- 4200254 TI - [Value of dihydrogenated ergot alkaloid combinations in the immediate postoperative period, particularly after extracorporeal circulation]. PMID- 4200253 TI - Studies of lipid A fractions from the lipopolysaccharides of Pseudomonas aeruginosa and Pseudomonas alcaligenes. AB - Lipid A fractions from Pseudomonas aeruginosa and Pseudomonas alcaligenes have similar compositions and structural features. By means of hydrazinolysis of the parent lipopolysaccharides and partial hydrolysis of the deacylation products, it was established that both lipids are derived from the beta-(1-->6)-linked disaccharide of glucosamine. Phosphorylated derivatives of the disaccharide from Ps. aeruginosa were also characterized. The lipids differ mainly in the absence of hexadecanoic acid and 2-hydroxydodecanoic acid from the lipid from Ps. alcaligenes. Evidence that in Ps. aeruginosa these acids are ester-linked to residues of 3-hydroxyalkanoic acids (including 3-hydroxydecanoic acid) was obtained. Heterogeneity of lipid A fractions was indicated by t.l.c., and by gel filtration of de-O-acylation products from mild alkaline methanolysis of the lipids. PMID- 4200256 TI - Alumina cream-induced focal motor epilepsy in cats. 2. Thickness and cellularity of cerebral cortex adjacent to epileptogenic lesions. PMID- 4200255 TI - [Multiply recurrent endocarditis caused by Enterococcus, cured by long term antibiotherapy at home]. PMID- 4200257 TI - Blockage of highly-stable "kindled" seizures in rats by antecedent footshock. PMID- 4200258 TI - Alumina cream-induced focal motor epilepsy in cats. 1. Lesion size and temporal course. PMID- 4200260 TI - Genetic factors in spike-wave absences. PMID- 4200259 TI - The significance of electroencephalographic paroxysms in children less than 3 years of age. PMID- 4200261 TI - Effect of trypsin and ethylenediamine tetra acetic acid on the rate of adhesion of KB cells. PMID- 4200262 TI - The effect of glibenclamide on non-esterified fatty acid levels in the plasma of the severely alloxan diabetic rat. PMID- 4200263 TI - Production of lesions in various tissues by amino acids. PMID- 4200264 TI - Antibodies to venous tissue in phlebothrombosis. PMID- 4200265 TI - A simple procedure for detecting proteins synthesized in organ cultures. PMID- 4200266 TI - Role of pili in the virulence of Neisseria gonorrhoeae. AB - Gonococci of the colonial types that are associated with virulence, types 1 and 2, have pili that enable the bacteria both to attach in vitro to human epithelial cells and to resist phagocytosis by polymorphonuclear leukocytes. These piliated gonococci also agglutinate various mammalian and chicken erythrocytes. Gonococci of an avirulent colonial type, i.e., type 4, have no pili and neither attach to epithelial cells or erythrocytes nor resist phagocytosis. Like the type 4 bacteria, mechanically or enzymatically (trypsin) depiliated type 1 gonococci failed to attach to epithelial cells and erythrocytes and were susceptible to phagocytosis. Pili of types 1 and 2 gonococci were antigenically similar. Both type 1 gonococci and pili isolated from them induced in rabbits antibody that (i) precipitated gonococcal pili in immunodiffusion, (ii) reacted with piliated gonococci as tested by indirect immunofluorescent analysis, (iii) inhibited attachment of piliated gonococci to both human epithelial cells and erythrocytes, and (iv) opsonized piliated gonococci. PMID- 4200267 TI - [Clinical and biologic aspects of para-osteo-arthropathy]. PMID- 4200268 TI - Local cerebral blood flow in experimental middle cerebral artery vasospasm. PMID- 4200269 TI - Vascular compression of the duodenum following severe brain injury. Case report. PMID- 4200271 TI - A re-examination of stereoscopic mechanisms in area 17 of the cat. PMID- 4200270 TI - [Staphylococcal enterotoxigens and enterotoxin in food, dietetic products and medicines for oral use. In vivo methods based on the emetic effect of enterotoxin]. PMID- 4200272 TI - The time course of the cerebral circulatory response to metabolic depression. PMID- 4200273 TI - [Absorption of penicillin V and digestive disorders]. PMID- 4200274 TI - [Influence of a social-emotional environmental stress on the functional status of neocortical structures in the rhesus monkey]. PMID- 4200275 TI - [Structural and immunochemical studies on carp immunoglobulins (Cyprinus carpio L.). I. Analysis of the total molecule]. PMID- 4200276 TI - The origin of life. PMID- 4200277 TI - Molecular hysteresis and its cybernetic significance. PMID- 4200278 TI - The cytochalasans: a new class of biologically active microbial metabolites. PMID- 4200279 TI - Iron-sulfur proteins: structural chemistry of their chromophores and related systems. PMID- 4200281 TI - [Prolonged parenteral nutrition in infants]. PMID- 4200280 TI - Ascending cholangitis after successful surgical repair of biliary atresia. PMID- 4200282 TI - 2-hydroxy-5-carbomethoxybenzyloxyamine: a new potent inhibitor of histidine decarboxylase. PMID- 4200283 TI - The actions of histamine on blood flow and capillary filtration coefficient (C.F.C.) in the cat small intestine. PMID- 4200284 TI - Impaired performance of delayed matching in monkeys by heptabarbitone, pentobarbitone sodium and guinalbarbitone sodium. PMID- 4200285 TI - Clinical problems of preventive medicine. The prevention and control of infectious ovine abortion. PMID- 4200286 TI - Wildlife review. The effects of pesticides on British wildlife. PMID- 4200287 TI - The survival of Brucella abortus in milk and milk products. PMID- 4200288 TI - Preliminary observations on a theilerial species pathogenic to cattle isolated from buffalo (Syncerus caffer) in Tanzania. PMID- 4200290 TI - Evidence for multiple forms of receptors for amiloride in transporting epithelia. PMID- 4200289 TI - Excretion of catecholamine metabolites following intraventricular injection of 6 hydroxydopamine in the Macaca speciosa. PMID- 4200291 TI - Improved purification of rat brain choline acetyltransferase by using an immunoabsorbent. PMID- 4200293 TI - Cytoplasmic transfer of RNA complementary to repetitious DNA sequences during early sea urchin embryogenesis. PMID- 4200292 TI - Radiochemical assay of UDP glucuronyltransferase (p-nitrophenol). PMID- 4200294 TI - [Morbidity risk in persons in contact with chronic tuberculosis patients]. PMID- 4200295 TI - [Morbidity through contact with tuberculous foci at the antitubercular dispensary of Tigru-Jiu]. PMID- 4200296 TI - Chemotherapy with hydroxyurea, leucopheresis and splenectomy in the treatment of chronic myeloid leukemia at the problastic phase. PMID- 4200298 TI - Chromosome alterations in chronic myeloid leukaemia, present aspects of the problem. PMID- 4200297 TI - Causes and genesis of myeloid leukemia. PMID- 4200299 TI - Chronic myelogenous leukemia: preleukemia or leukemia? PMID- 4200300 TI - Chronic myeloid leukaemia: advances in cytochemistry. PMID- 4200301 TI - Cell population growth in chronic myeloid leukaemia. PMID- 4200302 TI - Observations on the cytokinetics of chronic myeloid leukaemia. PMID- 4200303 TI - Blood coagulation abnormalities in chronic myeloid leukaemia. PMID- 4200304 TI - Immune reactions in chronic myeloid leukaemia. PMID- 4200305 TI - Studies on the genesis of anemia in chronic myeloid leukaemia--in vitro response of bone marrow cells to erythropoietin. PMID- 4200306 TI - A comparative essay of drugs in the treatment of chronic myeloid leukaemia. PMID- 4200307 TI - Clinical pharmacology of dibromohexitols. PMID- 4200309 TI - New trends in the management of chronic myeloid leukaemia. PMID- 4200308 TI - Dibromomannitol and chronic myeloid leukaemia results of a cooperative study. PMID- 4200310 TI - Treatment of the blastic phase of chronic myeloid leukaemia. A question to solve. PMID- 4200311 TI - Therapeutic experiences in chronic granulocytic leukaemia. PMID- 4200312 TI - Chronic myeloid leukaemia: course, life expectancy, and an analysis of dibromomannitol and busulfan treatment. PMID- 4200313 TI - Therapeutic effect of the removal of leukocytes by cell separator. PMID- 4200314 TI - Results in the treatment of chronic myeloid leukaemia. PMID- 4200315 TI - [An unusual oesophageal foreign body]. PMID- 4200316 TI - The affinity of mycobacterial glycopetides for guinea-pig gamma immunoglobulin and its fragments. PMID- 4200317 TI - Cellular immunity in experimental glomerulonephritis of rats. II. A sequential study of immunological events occurring during development of the disease. PMID- 4200318 TI - Conglutinating activity in apparently healthy human and animal sera. PMID- 4200319 TI - Purification and characterization of cytochrome b5-like hemoprotein associated with outer mitochondrial membrane of rat liver. PMID- 4200320 TI - Studies on ribosomal ribonucleic acid from yeast. I. Isolation and characterization of anomalous heavier 30 S robonucleic acid. PMID- 4200321 TI - The potential use of high-performance liquid chromatography in residue analysis. PMID- 4200323 TI - An outbreak of diphtheria in a hospital for the mentally subnormal. AB - An account is given of two separate outbreaks of diphtheria amongst mentally subnormal patients and nursing staff. In a total hospital population of about 1000 the number of people involved as carriers or cases was 60 and there were five deaths. The 60 people comprised 56 patients, of whom four were involved in both outbreaks, and four nurses. The organisms isolated were C. diphtheriae mitis but five strains were non-toxigenic. It is postulated that the outbreak began following the conversion of a non-toxigenic organism to a toxigenic one by bacteriophage action. The fatal cases were examples of membranous pharyngo laryngo-tracheo-bronchial diphtheria with well marked pseudo-casts of the upper air passages. PMID- 4200322 TI - An enzyme preparation inactivating all penicillins and cephalosporins. AB - Commercial penicillinases vary in their capacity to destroy penicillinase resistant penicillins and cephalosporins. A new freeze-dried preparation containing both beta-lactamase I and II was found to inactivate all penicillins and cephalosporins at levels above those likely to be encountered in clinical specimens. PMID- 4200324 TI - Experimental hypercalcaemia and whole blood clotting. AB - Experimental hypercalcaemia was induced in rats by (1) transplantation of the solid Walker 256 tumour, and (2) intraperitoneal injections of calcium gluconate. Whole blood clotting was studied by means of thromboelastography and whole blood clotting times in polystyrene and glass test tubes. At serum calcium levels between 10.3 and 11.5 m-equiv/l a slight delay in clot formation was found which was reversible by the addition of EDTA to whole blood. Acute, calcium-gluconate induced hypercalcaemia, however, leads to a significant shortening of the clotting time in the polystyrene tube and to a lesser degree in the glass tube. Maximal factor XII activation in vitro with ellagic acid levels the difference of clotting times again. From these experiments it is concluded that acute hypercalcaemia induces a hypercoagulable state, possibly by partial contact activation, and thus may favour thrombus formation in vivo. PMID- 4200326 TI - Measurement of myocardial blood flow by means of external counting method using 86-rubidium. PMID- 4200325 TI - The enterohepatic circulation of bile acids as they relate to lipid disorders. PMID- 4200327 TI - The catalytic mechanism of carbonic anhydrase. AB - It is shown that an "inverse" relationship between the pH dependencies of the rates of hydration of CO(2) and dehydration of HCO(3) (-) by carbonic anhydrase (EC 4.2.1.1) is a direct consequence of the thermodynamic equilibrium between CO(2) and HCO(3) (-) and independent of any assumptions about the catalytic mechanism. It is further shown that proposed mechanisms for carbonic anhydrase involving HCO(3) (-) as the substrate in the dehydration reaction and a proton transfer reaction, EH(+) right harpoon over left harpoon E + H(+), as an obligatory step during catalysis obey the rule of microscopic reversibility. This includes mechanisms in which the proton dissociation is from a zinc-coordinated water molecule. Such mechanisms can be in accord with the observed rapid turnover rates of the enzyme, since rapid proton exchange can occur with the buffer components, EH(+) + B right harpoon over left harpoon E + BH(+). Mechanisms in which H(2)CO(3) is the substrate in dehydration avoid the proton-transfer step, but require that H(2)CO(3) combines with enzyme more rapidly than in a diffusion controlled reaction. Physico-chemical evidence for and against a zinc-hydroxide mechanism is discussed. PMID- 4200328 TI - Metabolic demands after surgery. PMID- 4200329 TI - Intravenous nutrition: the materials available. PMID- 4200331 TI - Epidemiology of Chagas' disease and methods of detecting T. cruzi. PMID- 4200330 TI - Management of prolonged intravenous feeding. PMID- 4200332 TI - Immunology in cutaneous leishmaniasis. PMID- 4200333 TI - Transmission of hepatitis and Australia antigenaemia within a liver unit. PMID- 4200334 TI - Caffeine contractures in depolarized heart muscle. PMID- 4200335 TI - Clinical hypersensitivity states and serum protein modifications. PMID- 4200336 TI - [Results and limitations of long term therapy of diabetes mellitus]. PMID- 4200337 TI - [Preliminary clinical experiences and problems of long-term therapy of diabetes mellitus using 2nd generation sulfonylurea derivatives (glibenclamide)]. PMID- 4200338 TI - [Results of long-term therapy of diabetes mellitus using sulfonylurea compounds]. PMID- 4200339 TI - [Results of long-term treatment of hyperlipemias]. PMID- 4200340 TI - [Problems of long-term treatment of hyperlipoproteinemia with clofibrinic acid]. PMID- 4200341 TI - [Radiological diagnosis of the oesophagus]. PMID- 4200342 TI - [The spreading of organisms in aseptic departments by rubber overshoes]. PMID- 4200343 TI - [Ozone for disinfection of water contaminated with vegetative and spore forms of bacteria, fungi, and viruses]. PMID- 4200344 TI - [Determination of class-specific antibodies and immunoglobulins in colostral sera of protein-immunized cattle]. PMID- 4200345 TI - [Effects of leucocidine and hemolysin from Pseudomonas aeruginosa on granulocytes]. PMID- 4200347 TI - [Therapy with fast neutrons]. PMID- 4200346 TI - Coagulation of hyperglobulinaemic mink blood by glutaraldehyde. PMID- 4200348 TI - Right-sided bacterial endocarditis. New concepts in the treatment of the uncontrollable infection. PMID- 4200349 TI - Response to selection in synthetic lines of Drosophila melanogaster. PMID- 4200350 TI - The respiratory chain of Azotobacter vinelandii. I. Spectral properites of cytochrome d. PMID- 4200351 TI - Feedback controlling oxygen production in a cross-reaction between two photosystems in photosynthesis. PMID- 4200352 TI - The turnover times of photosynthesis and redox properties of the pool of electron carriers between the photosystems. PMID- 4200353 TI - The formation of pyrimidine dimers in the DNA of fungi and bacteria. PMID- 4200354 TI - The management of radiation caries. PMID- 4200355 TI - An investigation into the spread of bacterial infection in lower-limb amputations. PMID- 4200356 TI - Silver phosphanilamidopyrimidine. A new silver sulfadiazine analogue effective against Pseudomonas infection in burned mice. PMID- 4200357 TI - [Significance of E. coli serotyping for the control of chemotherapy in chronic pyelonephritis]. PMID- 4200358 TI - [Quantitative determination of immunoglobulins in the cerebrospinal fluid]. PMID- 4200359 TI - [Treatment with other penicillins in proven penicillin allergy?]. PMID- 4200360 TI - [Fibrosarcoma of the bladder after seven-year chemotherapy of Hodgkin's disease in childhood]. PMID- 4200361 TI - [Acrodermatitis enteropathica. Clinical picture, life-saving treatment, therapy induced blindness]. PMID- 4200362 TI - [Glucocorticoids in virus hepatitis]. PMID- 4200364 TI - Observations on the rates of ion movement and hypercapnia in aqueous humor. PMID- 4200363 TI - Cortical projection of group I muscle afferents to areas 2, 3a, and the vestibular field in the rhesus monkey. PMID- 4200365 TI - Purification of the human complement protein C1q by affinity chromatography. PMID- 4200366 TI - Expression of the a, x, and y variable region genes of heavy chains among IgG, IgM, and IgA molecules of normal and a locus allotype-suppressed rabbits. PMID- 4200367 TI - Detection of idiotypic determinants on human monoclonal proteins with specific rabbit antisera and hemagglutination-inhibition. PMID- 4200368 TI - Antigenicity of formaldehyde-inactivated staphylococcal enterotoxin B. PMID- 4200369 TI - Perimenstrual aggression in groups of female rhesus monkeys. PMID- 4200370 TI - [TRH test--interpretation of the test results]. PMID- 4200371 TI - [Thyroxine binding protein, free thyroxine and triiodothyronine--interpretation of the test results]. PMID- 4200372 TI - [Diabetic coma]. PMID- 4200373 TI - [Study of several factors producing a variation of the reversion frequency at the bobbed locus in Drosophila melanogaster (author's transl)]. PMID- 4200374 TI - The influence of the nucleolar organizer region on sperm utilization in Drosophila melanogaster. PMID- 4200375 TI - Asymmetric transcription of SPP1 in vivo. PMID- 4200376 TI - [Complement factors C'1-C'4) in maternal and infant serum in Rh-dependent hemolytic disease of newborn]. PMID- 4200377 TI - Dietary data and estimates of energy expenditure. PMID- 4200378 TI - [Formation of melanosome in the melanocyte (author's transl)]. PMID- 4200379 TI - [Lipids and synthesis of Tetrahymena pyriformis membrane (author's transl)]. PMID- 4200380 TI - The effects of stimulants and depressants on cocaine self-administration behavior in the rhesus monkey. PMID- 4200381 TI - Radiotherapy in the treatment of osteoarthrosis of the knee. PMID- 4200383 TI - [Detection of carbonic anhydrase by a photoelectric colorimetric method]. PMID- 4200382 TI - Respiratory disease in cork workers ("suberosis"). PMID- 4200384 TI - Light and electron microscopy of parathyroid carcinoma. Report of three cases. PMID- 4200385 TI - [Comparative scanning electron microscope investigations of bone in primary and secondary hyperparathyreoidism. The question of periosteocytic osteolysis (author's transl)]. PMID- 4200386 TI - Ectopical decidua formation in the ovary (so-called deciduoma). PMID- 4200387 TI - Repair in arterial tissue. A scanning electron microscopic (SEM) and light microscopic study on the endothelium of rabbit thoracic aorta following a single dilatation injury. PMID- 4200388 TI - Are interoceptive stimuli sufficient for instrumental conditioning? PMID- 4200389 TI - Lateral pterygoid: two muscles? PMID- 4200390 TI - Neurohistological observations on the heart of the Indian rhesus monkey, Macaca rhesus. PMID- 4200391 TI - Lymphoid cells converted by lymphoid RNA extracts in vitro and in vivo to synthesize allogeneic immunoglobulins. PMID- 4200392 TI - Interspecies "transfer" of delayed hypersensitivity in vitro with RNA extracts. PMID- 4200393 TI - Lactase-phlorizin hydrolase complex from monkey small intestine: stimulation of phlorizin hydrolase activity by organic acids. PMID- 4200394 TI - The use of glutaraldehyde fixation to analyze the mechanism of factor catalyzed reassociation of eukaryotic ribosomal subunits. PMID- 4200395 TI - Dissociation of eukaryotic ribosomes by purified initiation factor EIF-3. PMID- 4200396 TI - Isolation of carcinogenic aminoazo dye-binding protein and its identification as alcohol dehydrogenase. PMID- 4200397 TI - Affinity chromatography of thermolysin and of neutral proteases from B. subtilis. PMID- 4200398 TI - Multiple DNA polymerase activity solubilized from higher plant chromatin. PMID- 4200399 TI - Nucleus-associated RNA in measles virus-infected cells. PMID- 4200400 TI - Atomic coordinates for ferricytochrome c2 of Rhodospirillum rubrum. PMID- 4200402 TI - Detection of biliary tract disease at operation. PMID- 4200401 TI - The influence of sodium, potassium and lithium on the response of glycogen synthetase I to insulin and epinephrine in the isolated rat diaphragm. PMID- 4200403 TI - Prepacked milk feeds for continuous intragastric feeding. PMID- 4200404 TI - [Purification and properties of exocellular levan-sucrase from Bacillus subtilis Marburg]. PMID- 4200405 TI - Cryopreservation of infective particles of Theileria parva. PMID- 4200406 TI - The bacteriochlorophyll absorption band shifts linked with the energy state of photosynthetic bacteria membranes. PMID- 4200407 TI - Electron microscopy of incontinentia pigmenti. PMID- 4200408 TI - Kinetics of the two-sited enzyme. II. A method of distinguishing between anticooperative and independent active sites based on competitive inhibition. PMID- 4200410 TI - [Diagnosis and therapy of Hodgkin's disease]. PMID- 4200409 TI - Borna disease (BD), a slow virus infection. Biological properties of the virus. PMID- 4200411 TI - [Therapeutic value of choledochoduodenostomy in obstructive jaundice and concomitant pancreatitis]. PMID- 4200412 TI - Electron microscopy of intimal plaques following induction of large superficial mechanical injury (transverse injury) in the rabbit aorta. PMID- 4200413 TI - Comparative microspectrophotometric study of the DNA content in the diagnosis of pre-tumorous processes and cancer. PMID- 4200414 TI - On the presence of a concanavalin-A reactive coat over the endothelial aortic surface and its modifications during early experimental cholesterol atherogenesis in rabbits. PMID- 4200415 TI - Cytoplasmic fusions between liver parenchymal cells and infiltrating cells in chronic aggressive hepatitis. PMID- 4200416 TI - [Morphology and localization of hematoxylin-stained bodies in lupus nephritis]. PMID- 4200417 TI - [Symptomatic acute autoimmune haemolytic anaemia with incomplete thermo-auto antibodies in acute hepatitis (author's transl)]. PMID- 4200418 TI - [Bacteriology of chronic otitis media and the question of sensitivity to antibiotics (author's transl)]. PMID- 4200419 TI - [The influence of calcification and ossification of the thyroid cartilage in laryngeal trauma (author's transl)]. PMID- 4200420 TI - [Pharmacological comparison between tolbutamide and two second generation hypoglycemic sulfonylureas (glibenclamide and glisoxepide)]. PMID- 4200421 TI - Cytogenetic studies in protein-calorie malnutrition. PMID- 4200422 TI - Combining intra-abdominal arterial grafting with gastrointestinal or biliary tract procedures. PMID- 4200423 TI - Intrajejunal administration of an elemental diet at neutral pH avoids pancreatic stimulation. Studies in dog and man. PMID- 4200424 TI - Parenteral alimentation in infants and children with life-threatening illness. PMID- 4200425 TI - Selective inhibition of phagocytic activity of rabbit alveolar macrophages by cystic fibrosis serum. PMID- 4200426 TI - Computer files and analyses of laboratory data from tuberculosis patients. PMID- 4200427 TI - Serum alpha 1-antitrypsin variants. Prevalence and clinical spirometry. PMID- 4200429 TI - Organ-specific differences in the methylation of transfer RNA in vitro. PMID- 4200428 TI - Glomerular changes in acute plasmodium falciparum infection. An immunopathologic study. PMID- 4200430 TI - Oxidative activation of benz(a)anthracene and methylated derivatives in mutagenesis and carcinogenesis. PMID- 4200431 TI - Radioassay of serum folate. PMID- 4200433 TI - Scanning electron microscopy of human, monkey, and rabbit spermatozoa. PMID- 4200432 TI - Monkey ovarian contractility--its relationship to ovulation. PMID- 4200434 TI - Copper levels in tissues of rhesus monkeys bearing intrauterine or intra abdominal copper devices. PMID- 4200435 TI - [Endoscopic findings in the operated stomach]. PMID- 4200436 TI - [Esophagoscopy from the view point of an otorhinolaryngologist]. PMID- 4200438 TI - Blood groups, secretor status and ability to taste phenylthiocarbamide in some Muslim groups. PMID- 4200437 TI - Fertility of abnormal hemoglobin carriers in Porto Alegre, Brazil. PMID- 4200439 TI - Immunoglobulin characteristics of antibodies to malarial S-antigens in man. PMID- 4200440 TI - Structural changes in sheep antibody induced by interaction with polypeptide antigens. PMID- 4200441 TI - Oculomotor defects in cerebellectomized monkeys. PMID- 4200442 TI - Letter: Oculomotor control system. PMID- 4200443 TI - The phagolysosomal system of the pigment epithelium. A key to retinal disease. PMID- 4200444 TI - Platelet-induced vitreous membrane formation. PMID- 4200445 TI - Laser trabeculotomy in monkeys. PMID- 4200446 TI - Yersinia pseudotuberculosis infection in a Siberian tiger and a spider monkey. PMID- 4200447 TI - Undifferentiated salivary gland carcinoma in a baboon. PMID- 4200448 TI - Renal carcinoma in a rhesus monkey. PMID- 4200449 TI - Intraocular echinococcosis in a rhesus monkey. PMID- 4200450 TI - Indirect inguinal hernia in two baboons. PMID- 4200451 TI - Dermatophilosis (cutaneous streptothricosis) in owl monkeys. PMID- 4200452 TI - Pesticide effect on rumen microbial function. PMID- 4200453 TI - Destruction of psychrophilic strains of Bacillus by chlorine. PMID- 4200454 TI - Immunochemical and immunofluorescence studies of beta-trace protein in different species and organs, with special reference to the central nervous system. PMID- 4200455 TI - Ultraviolet absorption characteristics of myelin from the central nervous system. PMID- 4200456 TI - Inflammatory changes in the non-infected prostate gland. A clinical, microbiological and histological investigation. PMID- 4200457 TI - Unilateral diverticulum of the ureter: a case report and scanning electron microscopic study. PMID- 4200458 TI - Letter: RH sensitization associated with drug use. PMID- 4200459 TI - Letter: Mechanism of host specificity in malarial infection. PMID- 4200460 TI - Human x mouse somatic cell hybrid clone secreting immunoglobulins of both parental types. PMID- 4200461 TI - Transplantation of isolated pancreatic islets into the portal vein of diabetic rats. PMID- 4200462 TI - Cursive epilepsy and gelastic epilepsy. PMID- 4200463 TI - [Distribution of ABO and Rh blood groups in myocardial infarction]. PMID- 4200464 TI - [Pathophysiological aspects of the problem of parenteral nutrition]. PMID- 4200465 TI - Antiepileptic therapy and rickets in children. PMID- 4200466 TI - Applications of the electron beam in the treatment of cancer of the skin and lips. PMID- 4200468 TI - Lung corrections for 8-MV X rays. PMID- 4200467 TI - Relative surface doses from supervoltage radiation. PMID- 4200469 TI - [ECG in baboons (Papio hamadryas)]. PMID- 4200470 TI - Localization and content of thyrotrophin releasing factor (TRE) in median eminence of the hypothalamus. PMID- 4200471 TI - Peripheral plasma levels of oestrogen and progesterone in pregnant rhesus monkeys treated with dexamethasone. PMID- 4200472 TI - Peripheral plasma levels of oestrogens, progesterone and 17alpha hydroxyprogesterone during gestation in the rhesus monkey. PMID- 4200473 TI - Diagnosis of centrencephalic epilepsy with the use of ketamine chloride. PMID- 4200474 TI - Concordance of radioassay and microbiological assay in the study of the ethanol induced fall in serum folate level. PMID- 4200475 TI - Peripheral control of hormone metabolism. PMID- 4200476 TI - Anticomplementary hepatitis B antigen. Prognostic importance in chronic active liver disease. PMID- 4200477 TI - Protection with split and whole virus vaccines against influenza. PMID- 4200479 TI - Letter: Pathogenesis of measles. PMID- 4200478 TI - Plasma C3 and C4 concentrations in management of glomerulonephritis. AB - As part of a larger study of serial complement profiles in glomerulonephritis plasma C3 and C4 concentrations were measured using commercially available immunodiffusion plates. A total of 303 samples were obtained from 128 patients suffering from forms of nephritis associated with hypocomplementaemia-namely, lupus nephritis, mesangiocapillary glomerulonephritis (M.C.G.N.), and acute glomerulonephritis.These simple measurements of C3 and C4 gave clinically useful information. In lupus nephritis C3 and C4 generally correlated and C4 concentrations were more often and more profoundly depressed than C3 concentrations. Neither C3 nor C4 concentrations alone correlated well with the antinuclear factor titre.In both acute glomerulonephritis and M.C.G.N. the C3 concentrations were frequently lower than 20% of normal (which was never the case in patients with lupus), while the C4 concentration was usually normal and was almost never depressed in the absence of C3 depression. This suggests activation of complement at the C3 level by the "bypass" pathway in acute nephritis as well as in M.C.G.N., though both may be operating in some patients. In acute glomerulonephritis but not in M.C.G.N. C3 concentrations returned to normal within eight to 12 weeks.The two varieties of M.C.G.N. identified by the site of the deposits in the capillary glomerular walls differed in their C3 levels. In 10 patients with intramembranous dense linear deposits the C3 was always low over very long periods of time, rising in three out of four patients only after transplantation and immunosuppression. Other patients with M.C.G.N., in contrast, often showed normal C3 concentrations. Concentrations of C4 did not differ in either group, being normal in 80% of samples from all types. PMID- 4200480 TI - Letter: Prepacked milk feeds for continuous intragastric feeding. PMID- 4200481 TI - Resistance of Pseudomonas aeruginosa to gentamicin. AB - The resistance to gentamicin 4 mug./ml. of 250 Pseudomonas aeruginosa isolates was measured by a proportion method. Twenty-eight (11.2%) of the cultures fell into the most resistant group, in whose populations between 10 and 100% of the organisms were resistant. A relatively high percentage of urinary isolates and a comparatively low percentage of isolates from respiratory sources occurred in this group. Three of the 28 were resistant to carbenicillin 150 mug./ml. and 6 of 18 tested were as resistant to gentamicin 8 mug./ml. as they were to 4 mug./ml. The distribution of Ps. aeruginosa isolates between the different grades of resistance did not change significantly during the 10 months in which the survey was performed. PMID- 4200482 TI - Study on Saskatchewan community clinics suggests total health expenditure not less. PMID- 4200483 TI - Study on Saskatchewan community clinics suggests total health expenditure not less. Report's data and interpretation suspect. PMID- 4200484 TI - Study on Saskatchewan community clinics suggests total health expenditure not less. Report fails to deal with incentive issue for clinics physicians. PMID- 4200485 TI - Pharmacologic studies of camptothecin (NSC-100880): distribution, plasma protein binding, and biliary excretion. PMID- 4200486 TI - A new antitumor antimetabolite, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5 isoxazoleacetic acid (NSC-163501): antimicrobial reversal studies and preliminary evaluation against L1210 mouse leukemia in vivo. PMID- 4200487 TI - Motor behaviors of neonatal rhesus monkeys: measurement techniques and early development. PMID- 4200488 TI - Reversal learning in the neonatal rhesus monkey. PMID- 4200489 TI - Mother-infant separation in squirrel monkeys living in a group. PMID- 4200490 TI - [Decompensation of autonomous thyroid adenoma after long-term iodine intake (author's transl)]. PMID- 4200491 TI - [Serum and dialysate levels of corticosteroids in long-term haemodialysis (author's transl)]. PMID- 4200492 TI - [Endocarditis caused by aerobic corynebacteria (author's transl)]. PMID- 4200493 TI - [Letter: neomycin in hepatic coma]. PMID- 4200494 TI - [New technics of long term parenteral feeding for intestinal replacement. Use of an artificial intestine in 54 cases]. PMID- 4200495 TI - Plasma thyrotropin response to thyrotropin-releasing hormone in patients with pituitary and hypothalamic disorders. PMID- 4200496 TI - [Viruses in the pathology og the eye. I. Virus]. PMID- 4200497 TI - [Technical and organizational considerations in a Tumor Center equipped with high energy in the province of Potenza]. PMID- 4200498 TI - Inhibition of prostaglandin synthesis and the response of baboon cerebral circulation to carbon dioxide. PMID- 4200501 TI - Immunobiological entity of human leukemia reproduced in cayman. PMID- 4200499 TI - Immunization of female baboons with hapten-coupled gonadotropins. PMID- 4200500 TI - Plasma thyrotropin and its response to thyrotropin releasing hormone in normal pregnancy. PMID- 4200502 TI - Drinking as an avoidance response by the pigtail monkey (Macaca nemestrina). PMID- 4200503 TI - [Total open dislocation of the astragalus. Clinical and therapeutic considerations on a case]. PMID- 4200505 TI - [Hematogenous primary peritonitis caused by Salmonella paratyphi A]. PMID- 4200504 TI - [Gastric diverticulum associated with hyperchlorhydria]. PMID- 4200506 TI - Delayed recovery of function following orbital prefrontal lesions in infant monkeys. AB - Monkeys given orbital prefrontal lesions at 1, 4, or 8 weeks of age exhibited a severe learning disability when they were tested at 1 year of age, but showed substantial recovery by the time they were 2 years old. These results suggest that the protracted maturation of intact cortical regions is important in recovery of function after early brain injury. PMID- 4200507 TI - Letter: Carbon dioxide and pH: effect on species succession of algae. PMID- 4200508 TI - [Large field irradiations (mantle and Y fields) with 42-MV-photons in lymphogranulomatosis]. PMID- 4200509 TI - [Dose distribution of fast electrons and ultrahard photons in translation movement for large field irradiation at the betatron]. PMID- 4200510 TI - [Bisegmental pendulum irradiation of the aortal lymph nodes using deviation of the useful beam bundle with ultra hard x-rays from the 42 Me V-betatron]. PMID- 4200511 TI - The completion cholangiogram: failure to empty due to pseudo-obstruction. PMID- 4200512 TI - Preoperative preparation of the colon with an elemental diet. PMID- 4200513 TI - Temperature-sensitive mutants of toxinogenic corynebacteriophage beta. I. Genetics. PMID- 4200515 TI - [Proceedings: The position of disinfection and antisepsis in an antimicrobial regime (author's transl)]. PMID- 4200514 TI - Properties of an oncornavirus glycoprotein: evidence for its presence on the surface of virions and infected cells. PMID- 4200516 TI - In vitro action of bufexamac and selected hydroxamic acids on isolated rat liver lysosomes. PMID- 4200517 TI - Effect of glibenclamide upon 45 calcium efflux from perifused islets. PMID- 4200519 TI - Application of the radial immunodiffusion method to the study of IgG and the free light chains of immunoglobulins in the tubular and glomerular proteinuria. PMID- 4200518 TI - Suppression of acute and chronic inflammation in adrenalectomized rats by pharmacologic amounts of prostaglandins. PMID- 4200520 TI - The synthesis of nucleic acids in Bacillus subtilis infected with phage PBS 1. PMID- 4200521 TI - Structural studies on antigen E of ragweed pollen. PMID- 4200522 TI - Ocular abnormalities among congenitally deaf children. PMID- 4200523 TI - Preventive treatment of tuberculin-negative contacts. AB - Five children who had been in close contact with highly infectious tuberculous individuals presented recently to the tuberculosis service of The Montreal Children's Hospital. Four had developed serious pulmonary tuberculosis and one tuberculous meningitis, all within the three months which followed a post-contact negative tuberculin test.The management of tuberculin-negative children recently exposed to active infectious tuberculosis by repeated skin tests and chest radiography alone is inadequate for their protection. These children are at high risk of developing disease by the time their tuberculin sensitivity has become evident. It is inadvisable to vaccinate them with BCG until three months after their last exposure to the disease. A plea is made for preventive chemotherapy in these cases. PMID- 4200525 TI - [Combine Chinese and Western medicine in the treatment of pneumonia in children]. PMID- 4200526 TI - Diazepam and benzoctamlne: effects on certain objective parameters of muscular spasticity. PMID- 4200527 TI - Flurazepam versus diazepam in an anaesthesia: a clinical study. PMID- 4200528 TI - Comprehensive clinical studies with trazodone. PMID- 4200529 TI - A controlled study of the clinical effects of amantadine hydrochloride (Symmetrel). PMID- 4200530 TI - The comparative effects of SE1520, frusemide, and cyclopenthiazide in healthy subjects. PMID- 4200531 TI - Treatment of chronic staphylococcal osteomyelitis with minocycline hydrochloride: a case report. PMID- 4200532 TI - Attempts at prophylaxis for murine Pneumocystis carinii pneumonitis. PMID- 4200533 TI - Immunological properties of a trypanosomal lipopolysaccharide and its effects on the infection with Trypanosoma (Schizotrypanum) cruzi. PMID- 4200534 TI - Quantitative aspects of the migration inhibition reaction. PMID- 4200535 TI - Immunoadsorbent purification of antisera to impure abnormal serum antigens. Application to murine leukemia plasma virus. PMID- 4200536 TI - A factor in respiratory tract secretions interfering with the ammonium sulfate test of Farr. PMID- 4200537 TI - Rubella immunization of volunteers via the respiratory tract. AB - The efficacy of various routes of administration of the live attenuated rubella virus vaccine was evaluated by using 46 seronegative volunteers who were divided into 4 vaccine groups: subcutaneous, nosedrops, spray into posterior oropharynx and nose using large particle aerosol, and inhalation of small particle aerosol through the mouth. Seroconversion was observed in all of the vaccinees regardless of route of immunization. Nasal secretion antibody 6 weeks after immunization was highest in the volunteers who received the vaccine by nose drops (all members of this group had demonstrable nasal secretion antibody after immunization). Only half of the volunteers in the subcutaneous group developed demonstrable nasal secretion antibody. This suggests that nasal secretion antibody was best stimulated when vaccine was given directly into the nose. Volunteers were challenged with the vaccine intranasally at 6 to 8 weeks. None of the volunteers exhibited clinical symptoms or fourfold or greater serum antibody rises after challenge, but fourfold or greater nasal secretion antibody rises were observed in three volunteers in the subcutaneous vaccine group and two in the aerosol group, suggesting that those volunteers had not been protected against challenge. Rubella virus was isolated 8 to 12 days after challenge in two persons in the subcutaneous group and three in the aerosol vaccine group, but none in the nose drops or spray groups. Thus, protection after nasal challenge appeared to be best in those groups which also had the best nasal secretion antibody response after immunization. However, protection did not seem to be correlated with either nasal secretion or serum antibody levels. PMID- 4200539 TI - Mechanisms of immunity in typhus infections. I. Multiplication of typhus rickettsiae in human macrophage cell cultures in the nonimmune system: influence of virulence of rickettsial strains and of chloramphenicol. AB - Monocytes from the peripheral blood of nonimmune human subjects transformed in cell culture into macrophages with increased phagocytic capacity for killed typhus rickettsiae. When such cells were exposed to living virulent Rickettsia mooseri (Wilmington strain) or R. prowazeki (Breinl strain), or to the attenuated E strain of R. prowazeki, in the presence of medium containing normal human serum, all three strains readily entered the macrophage, but the subsequent fate varied according to strain and its virulence. Thus, R. mooseri grew readily to attain very high intracellular populations which eventually destroyed the macrophage in 3 to 5 days and escaped to infect other cells. Virulent R. prowazeki also grew at about the same rate for the first 2 to 3 days but then often abruptly ceased to multiply. Circumstantial evidence suggests a toxic effect on host cells by smaller numbers of R. prowazeki organisms than with R. mooseri. The attenuated E strain of R. prowazeki failed to grow in most cells and eventually disappeared, but did grow to substantial numbers in the very rare cell in some cultures, suggesting the presence of a few cells which may not be typical macrophages. The growth of R. mooseri in the macrophage cytoplasm was inhibited by chloramphenicol in the culture medium. When the drug was removed after 3 days, growth began after a lag period and assumed a normal rate. PMID- 4200538 TI - Transformation of lymphocytes in gonorrhea before and after therapy. AB - Patients were studied for lymphocyte transformation responses to a variety of Neisseria gonorrhoeae antigens and to a Neisseria catarrhalis sonicate. Cells from infected patients manifested significant uptake of tritiated thymidine in response to one or more gonococcal antigens. In some cases, deoxyribonucleic acid synthesis was so marked in lymphocytes not challenged by antigens in vitro that added blastogenesis was either obscured or inhibited. At five weeks posttherapy, lymphocytes were relatively nonreactive to gonococcal antigenic stimulation. Blastogenesis in response to N. catarrhalis was also seen for a few gonorrhea patients and normal controls. Cross-antigenicity of catarrhalis organisms and gonococci was indicated by the disappearance of reactivity to catarrhalis sonicate by the lymphocytes of almost all convalescent gonorrhea patients. PMID- 4200541 TI - Stimulation of anti-Brucella vaccination in mice by tetramisole, a phenyl imidothiazole salt. AB - The effect of tetramisole (hydrochloride of racemic 2, 3, 5, 6,-tetrahydro-6 phenyl-imidazo [2, 1-b] thiazole) on immunization was investigated in mice vaccinated by killed Brucella melitensis cells suspended in incomplete adjuvant. Immunity to Brucella abortus challenge was estimated by the reduction in number of B. abortus colonies per gram of spleen in those mice which escaped full immunization and also by calculation of mean infective doses for each group of mice. All tetramisole treatments significantly reduced the number of B. abortus live cells in spleen from infected mice. Tetramisole, injected twice (at the time of vaccination and 48 h later), induced a significant 3.5-fold increase of the protection brought about by Brucella vaccine alone. A single injection of 1.25 mg/kg at the time of vaccination resulted also in a significant increase of the immunity given by vaccination. No modifications of the vaccine potency were observed if tetramisole administration preceded vaccination. In such a mouse assay, tetramisole-induced stimulation was not accompanied by specific antibody increases, although measured by three serological tests. PMID- 4200540 TI - Immunological quantitation of hepatic tryptophan oxygenase in endotoxin-poisoned mice. AB - An apparent inhibition of induction of mouse hepatic tryptophan oxygenase by endotoxin has been reported previously, as evidenced by low catalytic activity. This could be due either to decreased tryptophan oxygenase levels or to inactivation of existing enzyme molecules. To resolve this question, the enzyme was quantitated immunologically in control and endotoxin-poisoned mice. Tryptophan oxygenase was purified and used as an antigen to prepare antienzyme antibodies. The antiserum was shown to be monospecific by immuno-electrophoresis. Addition of the antiserum to high-speed supernatant fluids of liver homogenates of control or endotoxin-poisoned mice resulted in precipitation of the enzyme. Radial immunodiffusion assays revealed that there was less enzyme in livers of mice that received 1 mean lethal dose of endotoxin. It was concluded that endotoxin interfered with the synthetic process that results in enhanced levels of tryptophan oxygenase. PMID- 4200542 TI - Effect of heat-labile factors on the neutralization of vaccinia virus by human. AB - The effect of unheated guinea pig and human prevaccination serum on the neutralization of vaccinia virus was studied. Enhancement of neutralization was found in all sera containing antibody and was more marked (20- to 150-fold) in sera obtained in the first weeks after primary vaccination than in sera from immune adults or cord sera (4- to 25-fold). The enhancing factor was thought to be complement because it was destroyed by heating and ethylenediaminetetraacetic acid treatment. The fresh serum-enhanced neutralization test represents a highly sensitive and specific test which can be applied to measure low levels of vaccinia antibody not detectable by other means. PMID- 4200543 TI - Antibody responses to meningococcal polysaccharide vaccines. AB - Over the past 4 years 19 lots of group C polysaccharide vaccine and five lots of group A polysaccharide vaccine have been tested for their immunogenicity in man. For each lot tested, groups of 18 to 50 men received 50 mug of vaccine subcutaneously. Sera were obtained prior to and 2 weeks after vaccination. The analytical and serological methods used in these studies were Sepharose 4B chromatography for the estimation of molecular size, the radioactive antigen binding assay, and the indirect hemagglutination (IHA) test for measuring the antibody response. Results have shown that the radioactive antigen binding assay is preferable to the IHA test as a measure of antibody response. Group C meningococcal vaccines have been highly stable when stored at 4 C in powdered form. All lots of group C vaccine tested to date have been of equal potency, with molecular weight varying from 520,000 to 2,000,000. Group A polysaccharides have been found to be unstable after 2 years of storage at 4 C. Optimal antibody response to the group A vaccines appears to be directly related to the molecular size of the preparation. PMID- 4200544 TI - Resistance to Mycoplasma synoviae is bursal dependent. AB - Bursectomizing small bursa line birds produced susceptibility to Mycoplasma synoviae. This suggested that M. synoviae is B cell dependent, but does not rule out a T cell effect. PMID- 4200545 TI - A system of intravenous hyperalimentation. PMID- 4200546 TI - Predictive oncology. 1. PMID- 4200547 TI - A new approach to diverticula of the inner part of the second duodenum. PMID- 4200549 TI - Is there a potential defect in the blood-retinal barrier at the choroidal level of the optic nerve canal? PMID- 4200548 TI - The fine structure of the retinal transient layer of Chievitz. PMID- 4200550 TI - Spectrofluorometric determination of carbidopa (L-(-)-alpha-hydrazino-3, 4 dihydroxy-alpha-methylhydrocinnamic acid) in plasma. PMID- 4200551 TI - [Pachydermoperiostosis (author's transl)]. PMID- 4200552 TI - Treatment of gonorrhea. Tetracyclines. PMID- 4200553 TI - II. Transportation systems in the diagnosis of gonorrhea. PMID- 4200554 TI - The role of diphosphonates in osteoporosis of disuse. PMID- 4200555 TI - Acute alterations in the bactericidal capacity of rabbit alveolar macrophages following stress. PMID- 4200556 TI - [Photosynthetic membranes of biliprotein-containing algae observed after freeze etching]. PMID- 4200557 TI - [Complications in closed injury to the pancreatico-duodenal area]. PMID- 4200558 TI - Biophysical characterization of a mitogenic erythro- and lympho-agglutinating phytohemagglutinin (PPHA) of Phaseolus vulgaris. PMID- 4200559 TI - Purification and some properties of isocitrate lyase from Pinus pinea. PMID- 4200560 TI - Performance under temporal schedules by monkeys with partial ablations of prefontal cortex. PMID- 4200561 TI - Comparison of behavioral effects of nicotine, d-amphetamine, caffeine and dimethylheptyl tetrahydrocannabinol in squirrel monkeys. PMID- 4200562 TI - Macromolecular synthesis and cell division in x-irradiated Tetrahymena. PMID- 4200563 TI - [Veterinary dentistry: paradentology in monkeys and beasts of prey]. PMID- 4200564 TI - Symposium: microsurgery of the outflow channels. Laboratory research. PMID- 4200565 TI - Pseudomonas aeruginosa contamination of hydrophilic contact lenses and solutions. PMID- 4200566 TI - Antibody and antibiotic action on Rickettsia prowazeki in body lice across the host-vector interface, with observations on strain virulence and retrieval mechanisms. PMID- 4200568 TI - Amniotic fluid creatinine in the Rh-sensitized pregnancy. PMID- 4200567 TI - Epidemiology of hepatitis B antigen in Panama. PMID- 4200569 TI - Umbilical blood flow, cardiac output, and organ blood flow in the immature baboon fetus. PMID- 4200570 TI - Effect of inotropic agents on canine trabecular muscle rendered highly permeable to calcium. PMID- 4200571 TI - Glycogen of the brain and vital organs of monkeys recovering from systemic ischemia. PMID- 4200573 TI - The free flap: composite tissue transfer by vascular anastomosis. PMID- 4200572 TI - Retinal laser damage thresholds as a function of image diameter. PMID- 4200574 TI - The effects of protein deprivation on dominance measured by shock avoidance competition and food competition. PMID- 4200575 TI - Significance of large red blood cells. PMID- 4200576 TI - Sialic acid deficiency of human red blood cells associated with persistent red cell, leucocyte, and platelet polyagglutinability. PMID- 4200577 TI - Evaluation of spinal inhibitory activity in epilepsy by the H wave recovery curve. PMID- 4200578 TI - Depamide in the treatment of epilepsy. A clinical trial. PMID- 4200579 TI - Psychological studies of patients with epilepsy and popular prejudice. PMID- 4200580 TI - Effect of head and body tilt on flicker-induced nystagmus in monkeys. PMID- 4200581 TI - Dietary management of diverticular disease. PMID- 4200582 TI - Bovine pyruvate kinases. I. Purification and characterization of the skeletal muscle isozyme. PMID- 4200583 TI - Homogeneous glycogen synthetase b from rat liver. PMID- 4200584 TI - Characterization of phycocyanin from Chromonas species. PMID- 4200585 TI - Microsomal electron transport. The role of reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase in liver microsomal lipid peroxidation. PMID- 4200586 TI - A new alpha-D-mannosidase occurring in Golgi membranes. PMID- 4200587 TI - Control of infectious hazards for the biophotographer. PMID- 4200588 TI - Prolactin release induced by synthetic thyrotrophin releasing factor in female rats. PMID- 4200589 TI - An in-vivo stimulatory effect of 3,3',5-tri-iodo-L-thyronine on polyphenol oxidase activity in an ascidian. PMID- 4200590 TI - Experimental infection of dogs and monkeys with two rabies serogroup viruses, Lagos bat and Mokola (IbAn 27377): clinical, serologic, virologic, and fluorescent-antibody studies. PMID- 4200591 TI - Exotoxins of Pseudomonas aeruginosa. I. Factors that influence the production of exotoxin A. PMID- 4200592 TI - Exotoxins of Pseudomonas aeruginosa. II. Concentration, purification, and characterization of exotoxin A. PMID- 4200593 TI - Exotoxins of Pseudomonas aeruginosa. 3. Characteristics of antitoxin A. PMID- 4200594 TI - Combinations of edetic acid and antibiotics in the treatment of rat burns infected with a resistant strain of Pseudomonas aeruginosa. PMID- 4200595 TI - Brief communication: a continuous in vitro source of Herpesvirus saimiri. PMID- 4200596 TI - Transformation of cell cultures as an indication of the carcinogenic potential of chemicals. PMID- 4200598 TI - Side effects of spasmolytic agents in the monkey. Intracisternal phenoxybenzamine and phentolamine. PMID- 4200597 TI - Hormonal regulation of rapidly labeled RNA in normal preneoplastic and neoplastic tissues of mouse mammary gland. PMID- 4200599 TI - A single method for measuring total thyroxine and free thyroxine index in serum. PMID- 4200600 TI - Antibody production in protein calorie malnutrition. PMID- 4200601 TI - Oxalosis caused by aspergilus infection. PMID- 4200602 TI - Letter: Effects of vitamin E: good and bad. PMID- 4200603 TI - Letter: Serology of toxoplasmosis, isosporosis and sarcosporidiosis. PMID- 4200605 TI - pH-dependent changes in composition of carcinoembryonic antigen. PMID- 4200604 TI - Prenatal hypothyroidism and brain composition in a primate. PMID- 4200607 TI - Letter: Infection and transformation of bovine lymphoid cells in vitro by infective particles of Theileria parva. PMID- 4200606 TI - Ventilation of toad lungs in the absence of the buccopharyngeal pump. PMID- 4200608 TI - Fetal infection of the baboon (Papio cynocephalus) with vaccinia virus. PMID- 4200609 TI - Comparison of temperature and pH effects on cells, walls, and autolysin of Listeria monocytogenes. PMID- 4200610 TI - Comparative effects of ovarian steroids on glycogen metabolism of rat, rabbit and guinea pig uterine tissue. PMID- 4200611 TI - Early life nutritional deprivation: persistent alteration of blood and urine amino acids in mice. PMID- 4200612 TI - Calcification and decalcification rates in vitro. A new technique. PMID- 4200614 TI - Diamide: a new radiosensitizer for anoxic cells. PMID- 4200613 TI - Responses of rat kidney and toad bladder to the pentapeptide ring structures of neurohypophysial hormones. PMID- 4200615 TI - Diagnostic and prognostic value of some tests of autoimmune hemolytic anemia in diseases of the lymphoreticular system. PMID- 4200616 TI - Anthrax in Iran. PMID- 4200618 TI - Correlation between oestriol levels and serum iron-binding capacity in pregnancy. PMID- 4200617 TI - Oxymetholone treatment in hypoproliferative anaemia. I. Frequency of response. PMID- 4200619 TI - Quantitative studies of macrophages in blood cultures in chronic lymphocytic leukaemia. PMID- 4200620 TI - A new anomaly of platelet aggregation. A report of two families. PMID- 4200621 TI - Thrombocytopathia with abnormalities in platelet release reaction. Some evidence for platelet factor 4 deficiency. PMID- 4200622 TI - Screening of blood donors for hepatitis-associated antigen and antibody. PMID- 4200623 TI - Automated seroagglutination test with Brucella and salmonella suspensions. PMID- 4200624 TI - Implant with postoperative drain after evisceration. PMID- 4200626 TI - Selection of treatment in squamous carcinoma of the floor of the mouth. PMID- 4200625 TI - The effect of tobramycin on Pseudomonas keratitis. PMID- 4200627 TI - Clinical evaluation of a 10 percent intravenous fat emulsion for parenteral nutrition in thermally injured patients. PMID- 4200629 TI - Total body potassium measurements as a guide to intravenous alimentation. PMID- 4200628 TI - Effects of estrogen upon bile: implications with respect to gallstone formation. PMID- 4200630 TI - Effects of various gases on the survival of dried bacteria during storage. AB - Salmonella newport and Pseudomonas fluorescens were dried together in papain digest broth and sucrose-glutamate, and stored in several gases at various water activities (a(w)) between 0.00 and 0.40 at 25 C for various periods up to 81 weeks. Both S. newport and P. fluorescens, dried in papain digest broth and stored in air, died rapidly if the conditions were very dry (0.00 a(w)) or moist (0.40 a(w)). Storage in carbon dioxide and argon gave greater survival than storage in air but lower survival than did storage in nitrogen or in vacuo. When the organisms were dried in a sucrose-glutamate mixture the differences between the gases were very small, and variations in residual water were less important. Of the inert gases, argon gave the best survival when the organisms were dried in papain digest broth, especially at 0.00 a(w); the survival in neon and krypton was lower and in xenon and helium it was much lower. PMID- 4200631 TI - Rapid method for detection of Pseudomonas aeruginosa on MacConkey agar under ultraviolet light. AB - A simple screening technique for the detection of Pseudomonas aeruginosa colonies by their fluorescence on MacConkey agar under ultraviolet light is proposed. From 306 nonlactose fermenting cultures screened under the ultraviolet light, 108 fluorescent isolates were obtained. These were screened biochemically, with 103 (94.8%) being verified as P. aeruginosa. From the 198 nonfluorescing cultures, only one suspected P. aeruginosa was isolated. PMID- 4200632 TI - The perforated diverticulum of the duodenum. PMID- 4200633 TI - Continuous pressure monitoring in experimental obstructive hydrocephalus. I. The dynamics of acute ventricular obstruction. PMID- 4200634 TI - Continuous pressure monitoring in experimental obstructive hydrocephalus. II. The origin of undulating ventricular waves and periodic respirations. PMID- 4200635 TI - On porcine enterokinase. Further purification and some molecular properties. PMID- 4200636 TI - The identification of a unique p-nitrophenol conjugating enzyme in guinea pig liver microsomes. PMID- 4200637 TI - On the relation of heavy metals to the activity and heat stability of alkaline phosphatase from human placenta. PMID- 4200638 TI - Experimental kuru in the chimpanzee. A neuropathological study. PMID- 4200639 TI - Altered response to scrapie tissues in neurological disease. Possible evidence for an antigen associated with reactive astrocytes. PMID- 4200640 TI - Digitalis as an antianginal agent. PMID- 4200641 TI - Interstitial pulmonary fibrosis and von Recklinghausen's disease. An ultrastructural and immunofluorescent study. PMID- 4200642 TI - Endobronchial tuberculosis. PMID- 4200643 TI - Incontinentia pigmenti: a systemic genodermatosis with striking cutaneous findings. PMID- 4200644 TI - Gonococcal infections in infants and children. Lessons from fifteen cases. PMID- 4200645 TI - Surgical aspects of nontuberculous bacterial meningitis in infancy and childhood. The successful use of conservative surgery in management of some of its complications. PMID- 4200646 TI - Some recent concepts on anterior pituitary control. PMID- 4200647 TI - Suppression of chicken immunoglobulin ontogeny by F(ab')2 fragments of anti-mu chain and by anti-L chain. PMID- 4200648 TI - Synthesis, intracellular distribution, and secretion of immunoglobulin and H-2 antigen in muring splenocytes. AB - A/J spleen cells were labeled with [(3)H]leucine and at intervals thereafter were homogenized and separated into microsomes and cell sap. Ig and H-2 antigens were assayed in the cell fractions and cell supernatants using immunoprecipitation. In addition, cells labeled by enzymatic radioiodination were incubated to determine the rates of release of Ig and H-2 antigens from the surface. The results indicate that the majority of Ig and H-2 antigens remain membrane bound throughout their intracellular life. In contrast to Ig, H-2 antigens are neither secreted nor shed from the cell surface. It is suggested that Ig is a peripheral protein of the cell membrane, whereas H-2 antigens are integral ones. The release of Ig on a fragment of plasma membrane could occur at fixed cell surface areas that contain no H-2 antigens or from which they have migrated before release. PMID- 4200649 TI - The enhancement of macrophage bacteriostasis by products of activated lymphocytes. AB - It was reported previously that the incubation of normal guinea pig macrophages with partially purified products of activated lymphocytes resulted in altered macrophage function including increased cell adherence to culture vessels, spreading, phagocytosis, and glucose carbon-1 oxidation. Studies reported here demonstrate that such macrophages also exhibit enhanced bacteriostasis. Lymphocytes were stimulated with concanavalin A, the culture supernatant was chromatographed over Sephadex G-100 and the fraction of mol wt 25,000-55,000, rich in lymphocyte mediators, was cultured with normal guinea pig macrophages for 1-3 days. Macrophages incubated with fractions from unstimulated lymphocyte cultures served as controls. The resulting macrophage monolayers were infected with Listeria monocytogenes. Macrophages incubated with mediator-rich fractions exhibited 2- to 10-fold enhanced bacteriostasis compared to controls. Further studies indicate that this enhancement was attributable to intrinsic changes in the macrophages and not simply a consequence of the number of macrophages on the monolayers. The studies support the concept that macrophage bacteriostasis can be enhanced by lymphocyte mediators. However, macrophages, which have been preincubated directly with sensitive lymphocytes and antigen exhibit even greater bacteriostasis and sometimes bactericidal capacity, suggesting that either a labile lymphocyte factor or direct lymphocyte macrophage interaction may also be involved in bactericidal activity. PMID- 4200651 TI - In vitro activity of cefazolin against recent clinical bacterial isolates. PMID- 4200652 TI - Comparative activity of bacterial beta-lactamases on penicillins and cephalosporins. PMID- 4200653 TI - Studies on therapy of staphylococcal infections in monkeys. 8. Comparison of cephalothin, cephaloridine, cefazolin, cephacetrile, and cephanone. PMID- 4200650 TI - Monoclonal macroglobulinemia in NZB-NZW F1 mice. AB - Serum monoclonal macroglobulins were detected in over 30% of NZB/NZW F(1) mice greater than 11 mo of age. The monoclonal nature of the IgM was shown by restricted electrophoretic mobility, characteristic appearance on immunoelectrophoresis, restriction to a single light chain type, and ability to induce anti-idiotypic antisera. The monoclonal macroglobulins were separated from antibodies to DNA and RNA that migrated in the 7S region of sucrose gradients. Enlarged lymph nodes were often present in mice with monoclonal IgM, and a transplantable IgM-producing lymphoid tumor was established from the spleen of one animal. PMID- 4200654 TI - Cefazolin in the treatment of gonorrhea. PMID- 4200655 TI - Cefazolin in the treatment of uncomplicated gonorrhea in men. PMID- 4200656 TI - Tularaemic pneumonia: pathogenesis of the aerosol-induced disease in monkeys. PMID- 4200657 TI - The natural history of platelet-rich mural thrombi in systemic arteries of hypercholesterolaemic monkeys: light- and electron-microscope observations. PMID- 4200658 TI - A clinical and histologic assessment of subperiosteal implants. PMID- 4200659 TI - The effect of human granulocyte elastase on bacterial suspensions. PMID- 4200660 TI - Short small-bowel syndrome. PMID- 4200661 TI - Prophylaxis against septicaemia in acute leukaemia: the use of oral framycetin. PMID- 4200662 TI - Microbiological studies on non-gonococcal urethritis in Brisbane. PMID- 4200663 TI - Cromolyn sodium. PMID- 4200665 TI - Intramembranous particle aggregation in lymphoid cells. PMID- 4200664 TI - Prostaglandin production and bone resorption by dental cysts. PMID- 4200666 TI - Gammopathy in hamsters with xenogeneic tumours. PMID- 4200668 TI - [Duodenal diverticulum in a 12-year-old child]. PMID- 4200667 TI - Effect of neuroleptics on aggressive behavior. PMID- 4200669 TI - The intranuclear development of Toxoplasma. PMID- 4200670 TI - The transmission of Sarcocystis tenella in sheep. PMID- 4200671 TI - The effect of heterologous anti-thymocyte serum upon the course of infection with Trypanosoma cruzi in Mice. PMID- 4200672 TI - [Antigenic analyses and cross reactions between Leishmaniae, Trypanosoma cruzi and Mycobacterium smegmatis (author's transl)]. PMID- 4200673 TI - Studies on colostral antibodies to Theileria parva using the indirect fluorescent antibody test. PMID- 4200674 TI - Chagas' heart disease. First demonstrable correlation between neuronal degeneration and autonomic impairment. PMID- 4200675 TI - Pharmacological comparison between tolbutamide and two second generation hypoglycemic sulfonylureas (glibenclamide and glisoxepide). PMID- 4200676 TI - Left ventricular function in patients with coronary artery disease. PMID- 4200677 TI - Myocardial transit times from intracoronary dye-dilution curves in normal subjects and patients with coronary artery disease. PMID- 4200678 TI - Renovascular hypertension in the pediatric patient. PMID- 4200680 TI - Tactile discrimination performance in the monkey: the effect of commissure section on transfer of training between the hands. PMID- 4200679 TI - Development of large-scale fractionation methods. IV. A simple method for the large-scale preparation of alpha1-acid glycoprotein. PMID- 4200681 TI - [Investigations into the action of skin disinfectants on bacterial spores (author's transl)]. PMID- 4200683 TI - [Discussion on methadone programs in the Federal Republic of Germany]. PMID- 4200682 TI - [Nutrition problems in the postoperative phase]. PMID- 4200684 TI - Studies on the biosynthesis of malate dehydrogenase isozymes in rabbit liver. Isolation of the in vivo labelled isozymes by specific antibodies. PMID- 4200685 TI - Hydrosoluble adjuvant-active mycobacterial fractions of low molecular weight. PMID- 4200686 TI - Genetic control of insect population. I. Cage studies of chromosome replacement by compound autosomes in Drosophila melanogaster. AB - A genetic method for insect control was evaluated using the test organism, Drosophila melanogaster. The technique involved the displacement under a system of continuous reproduction, of standard strains by those carrying compound autosomes. The eradication of the replacements could subsequently be achieved through the use of temperature-sensitive lethal mutations.-While certain compound autosome strains failed to displace standards in population cages, even at the initial release ratio of 25:1, others were highly successful. Indeed, for some strains when the ratio of compounds to standards was as low as 9:1, the population rapidly went to fixation in favor of the compound line.-Hatchability was found to be an insufficient index of fitness to estimate the initial ratios of compounds to standards that would guarantee fixation of the former. Differences in other fitness components, such as development time, were detected that could seriously modify displacement, especially with continuous overlapping generations. The importance of examining the fitness of various compound lines and selecting the most competitive in cages, prior to field tests, cannot be overemphasized. PMID- 4200687 TI - Differential response to selection on the two sexes in Drosophila melanogaster. AB - Artificial selection for short wing was performed in two Drosophila melanogaster populations with partially different gene pools: the C populations were derived from a Canton stock while the H lines were derived from a cross between Canton and a b, cn, vg strain. It is shown that in both populations selection on females (CF, HF) was more effective than selection on males (CM, HM). This difference cannot be explained in terms of differences in additive genetic variability between the two sexes because: (1) both sexes contribute to the genetic variability utilized by selection applied to one sex only, and (2) switching selection pressure on females in the M lines does not result in a response comparable to that obtained in the F populations; this rules out almost completely recombination as the responsible agent for the differences between the selection limits reached by M and F selections.-These results, together with several additional observations concerning sexual dimorphism, fitness and the effect of natural selection, suggest that a complex interaction should be involved in the differential response of M and F lines, controlling the wing length phenotype. PMID- 4200688 TI - On the genetics of the primary generalized epilepsy with sporadic myoclonias of impulsive petit mal type. A clinical and electroencephalographic study of 399 probands. PMID- 4200689 TI - A convenient method for liquid scintillation counting of barium carbonate-14C. PMID- 4200690 TI - Anthrax in Louisiana, 1971: an evaluation of the Sterne strain anthrax vaccine. PMID- 4200691 TI - Anthrax in Louisiana, 1971: epizootiologic study. PMID- 4200692 TI - A gas chromatographic method of quantitating DDT in the presence of interfering polychlorinated biphenyl. PMID- 4200693 TI - Electroencephalographic correlates of delayed-alternation and visual discrimination learning in rhesus monkeys. PMID- 4200694 TI - Isolation of glucosamine from the capsids of a picornavirus. PMID- 4200695 TI - Long term infection of diploid African green monkey brain cells by Schwarz measles vaccine virus. PMID- 4200696 TI - Anthrax. Biological and immunological principles of diagnosis and prevention. Communication 7. Diagnosis of anthrax by means of anthraxin. PMID- 4200697 TI - Effect of glucose or glycerin in cultivation media on the fatty acid composition of Listeria monocytogenes. PMID- 4200698 TI - Serum immuno-globulins in children with bilharzial infection. PMID- 4200699 TI - Localization of calcium antimonate in the atrial and ventricular muscle fibers of the cat heart. PMID- 4200700 TI - Transmission of three strains of Plasmodium falciparum from monkey to man. PMID- 4200701 TI - Studies on human malaria in aotus monkeys. 3. Exoerythrocytic stages of the Salvador II strain of Plasmodium vivax. PMID- 4200702 TI - Difference in surface charge between host cells and malarial parasites. PMID- 4200703 TI - Failure of holothurin to significantly affect Chagas' disease in mice. PMID- 4200704 TI - Effect of progesteroids on the cellular response to inflammation in the monkey. PMID- 4200705 TI - Virulence of rifampicin-resistant mutants of Shigella and enteropathogenic Escherichia coli with special reference to their cell invasiveness. PMID- 4200706 TI - Slime production by Pseudomonas aeruginosa. 3. Purification of slime and its physicochemical properties. PMID- 4200707 TI - [The cryptophthalmus syndrome (author's transl)]. PMID- 4200708 TI - Physicochemical investigation of DNP preparations obtained at low ionic strength. PMID- 4200709 TI - Triazenes, a new group of indirect mutagens. Comparative investigations of the genetic effects of different Aryldialkyltriazenes using Saccharomyces cerevisiae, the host-mediated assay, Drosophila melanogaster, and human chromosomes in vitro. PMID- 4200711 TI - Comparative mutagenic activity and toxicity of triethylphosphate and dichlorvos in bacteria and Drosophila. PMID- 4200710 TI - [Mutagenicity and toxicity tests with captan in Drosophila (author's transl)]. PMID- 4200712 TI - Invited discussion: Approaches to the serologic characterization of Hodgkin's disease. PMID- 4200713 TI - Invited discussion: Tumor-associated antigen in Hodgkin's disease. PMID- 4200714 TI - Complications of intensive megavoltage radiotherapy for Hodgkin's disease. PMID- 4200715 TI - Modern radiotherapy in carcinoma of the larynx. PMID- 4200716 TI - Endoscopic treatment of esophageal diverticula. PMID- 4200717 TI - Glycogen metabolism of human diploid fibroblast cells in culture. I. Studies of cells from patients with glycogenosis types II, 3, and V. PMID- 4200718 TI - Mucolipidosis 3 (Pseudo-Hurler polydystrophy): multiple lysosomal enzyme abnormalities in serum and cultured fibroblast cells. PMID- 4200719 TI - Meningococcal meningitis presenting as acute cerebellar ataxia. PMID- 4200720 TI - Inactivation of enzymes induced by substrate: a model and some considerations. PMID- 4200721 TI - Primer activity of a low molecular weight glycogen from a patient with an unusual glycogen storage disease. PMID- 4200722 TI - Differentiation in Nostoc muscorum: nitrogenase is synthesized in heterocysts. AB - Cellular differentiation can be observed in certain filamentous blue-green algae after transfer of the cells from medium containing NH(4) (+) or NO(3) (-) to nitrogen-free medium. The appearance of differentiated cells (heterocysts) is accompanied by an increase in the activity of nitrogenase, an enzyme complex that reduces N(2) to NH(3). We have separated vegetative cells from heterocysts in differentiated filaments of Nostoc muscorum, and analyzed their proteins by polyacrylamide-gel electrophoresis. The pattern of incorporation of (35)SO(4) (-) into proteins of the two cell types during differentiation indicates that the increase in nitrogenase activity is due to the de novo synthesis of nitrogenase proteins predominantly, if not exclusively, in heterocysts. PMID- 4200723 TI - Human phosphoribosylpyrophosphate synthetase: increased enzyme specific activity in a family with gout and excessive purine synthesis. AB - Among affected members of a family (B. family) with excessive purine production and gout, activity of phosphoribosylpyrophosphate synthetase (EC 2.7.6.1) is 2.5- to 3.0-fold higher than among normal people. The molecular basis for this increased enzyme activity was studied. Antibody to purified human phosphoribosylpyrophosphate synthetase of erythrocytes was obtained from immunized rabbits. Studies with the IgG fraction of this antiserum show the presence of normal quantities of immunoreactive enzyme, but 2.5- to 3.0-fold higher activity per molecule in affected members of the B. family. In addition, by use of a stain for phosphoribosylpyrophosphate synthetase activity, a difference in electrophoretic mobility was demonstrated on cellulose acetate gel between the partially purified enzyme from normal people and an affected member of the B. family. These studies suggest that the enzyme aberration responsible for purine overproduction and gout in the B. family results from a structurally altered enzyme with increased activity per molecule. PMID- 4200724 TI - Strychnine binding associated with glycine receptors of the central nervous system. AB - [(3)H]Strychnine binds to synaptic-membrane fractions of the spinal cord in a selective fashion, indicating an interaction with postsynaptic glycine receptors. Displacement of strychnine by glycine and other amino acids parallels their glycine-like neurophysiologic activity. The regional localization of strychnine binding in the central nervous system correlates closely with endogenous glycine concentrations. In subcellular fractionation experiments, strychnine binding is most enhanced in synaptic-membrane fractions. Strychnine binding is saturable, with affinity constants for glycine and strychnine of 10 and 0.03 muM, respectively. PMID- 4200725 TI - Proton-coupled accumulation of galactoside in Streptococcus lactis 7962. AB - When cells of the anaerobe Streptococcus lactis 7962 are deprived of their normal fermentable energy source, active transport of galactosides is completely abolished although the membrane carriers are still capable of facilitating the equilibration of sugars across the cell membrane. In these nonmetabolizing cells it was possible to test the Mitchell hypothesis of obligatory coupling of proton movement with sugar transport. This hypothesis was supported by alkalinization of the medium observed when thiomethylgalactoside was added to a lightly buffered suspension of S. lactis cells. Conversely, addition of protons resulted in active transport of thiomethylgalactoside. Accumulation of thiomethylgalactoside to a concentration more than 20-times that in the external medium was induced by suddenly exposing cells to a medium at pH 6; no accumulation of thiomethylgalactoside was observed with cells exposed to pH 8.Active transport of thiomethylgalactoside occurred in the absence of energy metabolism when S. lactis cells were treated with valinomycin. This ionophore allowed intracellular K(+) to flow out, thus imposing a membrane potential (inside negative). This potential resulted in a proton uptake and an associated active transport of galactoside. The membrane potential was measured from the distribution ratio (inside/outside) of K(+) in the presence of valinomycin. The pH gradient was measured from the distribution ratio of [(14)C]methylamine. The protonmotive force, calculated from the membrane potential and the pH gradient, was found to be directly related to the accumulation of galactoside, in accordance with the chemiosmotic hypothesis. PMID- 4200726 TI - Survey of DNA polymerase activity during the early development of Drosophila melanogaster. AB - The pattern of DNA polymerase activity in developing Drosophila melanogaster has been studied in seven stages of embryonic development as well as in unfertilized eggs. The crude polymerase-containing extracts, most likely of cytoplasmic origin, utilize, in the following order of decreasing template efficiency, "activated" calfthymus DNA, poly(A).oligo(dT), and poly(A).oligo(U). The highest enzymes levels occur in unfertilized eggs; the activity remains high during the first 9 hr of embryogenesis, but shows a progressive decline in the later stages. Deoxyribonuclease exhibits a similar trend. The unfertilized eggs of two genotypically different females had nearly identical levels of DNA polymerase. PMID- 4200728 TI - Australia antibody production elicited by heat-treated human plasma protein solution. PMID- 4200727 TI - Relation of detergent HLB number to solubilization and stabilization of D-alanine carboxypeptidase from Bacillus subtilis membranes. AB - The ability of various nonionic detergents to solubilize D-alanine carboxypeptidase and other membrane-bound enzymes was correlated to a physical property of the detergent, the HLB number. Only a fairly narrow range of detergents were effective solubilizing agents. Purified carboxypeptidase required either a detergent or detergent plus a lipid fraction for stability. Only those detergents effective in solubilizing the enzyme were effective in stabilizing it. PMID- 4200729 TI - The production in the pregnant cow of anti-human immunoglobulin to be used for the antiglobulin test. PMID- 4200730 TI - Evidence of the existence of the rhesus complex Cde (r') in a Chinese. PMID- 4200731 TI - The treatment of angina pectoris. PMID- 4200732 TI - [Stimulation of the hypophyso-thyroid system during the perinatal period]. PMID- 4200733 TI - Sequenced external counterpulsation and intraaortic balloon pumping in cardiogenic shock. PMID- 4200734 TI - Visual defect does not produce stereotyped movements. PMID- 4200735 TI - Central effects of 6-hydroxydopamine. PMID- 4200736 TI - A statistical method for the classification of behavior untis occurring in primate communication. PMID- 4200737 TI - [Lipoxygenase of horse bean (Vicia faba L.). I. Isolation]. PMID- 4200739 TI - The ribosomal cycle in bacteria treated with an inhibitor of protein synthesis. PMID- 4200738 TI - Comparative methods for isolation of polysomes from the oviduct of laying hen. PMID- 4200740 TI - Studies on the bacteriophage MS2. XXII. Conformation of MS2 RNA in acid medium. PMID- 4200742 TI - Quantitative differentiation of Yersinia pestis strains by their murine toxin and fraction I contents. AB - Until now the serological typing of Yersinia pestis into subgroups has not proved possible because all the antigenic components are present in each isolate. Using acrylamide disk electrophoresis it was observed that differences exist in the protein distribution patterns of aqueous extracts from various Y. pestis isolates. One component that was especially plentiful in some Javanese and South American isolates was identified as the murine toxin. The amount of murine toxin varies significantly from isolate to isolate, and so permits them to be roughly grouped. In 28 degrees C cultures the variation in the murine toxin content is independent of the variation in the F-I content. A new method of typing based on this 2-trait variation in quantities, in contrast to classical typing based on qualitative differences, might prove to be a means of differentiating Y. pestis isolates. PMID- 4200741 TI - Antigenic variation in current human type A influenza viruses: antigenic characteristics of the variants and their geographic distribution. AB - Outbreaks of influenza due to the virus A/Hong Kong/1/68 (H3N2) began in 1968 and are still occurring. The haemagglutinin of this virus is different from that of the A/Singapore/1/57 virus (the "Asian" strain) but the neuraminidase antigens are the same. Between 1968 and 1971 only minor antigenic "drift" in the haemagglutinin was noted, but in recent months 2 isolates have been identified in which considerable "drift" has occurred in the haemagglutinin and in the neuraminidase antigens. One, A/Hong Kong/5/72 (H3N2), was first detected in outbreaks in Hong Kong between November 1971 and January 1972 and was predominant there and in Korea but did not become widely disseminated. The second strain, A/England/42/72 (H3N2), has been isolated in winter outbreaks in the southern hemisphere and now appears to be the predominant strain in the northern hemisphere. The characteristics of the strains are described. PMID- 4200743 TI - [Early detection of esophageal neoplasms]. PMID- 4200744 TI - [Pathological basis for radiodiagnosis of ulcerative carcinoma and benign stomach ulcer]. PMID- 4200745 TI - [Antineoplastic effect and toxicity of the alkaloid of Crotalaria assamica]. PMID- 4200746 TI - [Indirect latex-leptospiral agglutination and inhibition test for the diagnosis of leptospirosis]. PMID- 4200747 TI - [Comparison of affects of bephenium hydroxynaphthoate, tetramisole hydrochloride and tetramisole pamoate in the treatment of Ancylostoma duodenale and Necator americanus infections]. PMID- 4200748 TI - [Anisodamine in the treatment of severe toxic bacillary dysentery]. PMID- 4200749 TI - [Treatment with Kushen Chinpi decoction in 50 cases of acute bacillary dysentery in children]. PMID- 4200750 TI - [Re-implantation of an amputated finger]. PMID- 4200751 TI - [Experience in treating burns chiefly with Chinese herb medicine]. PMID- 4200752 TI - [Recent development in cancer chemotherapy]. PMID- 4200753 TI - [Clinicopathological discussion. No. 6. Progressive weight loss, weakness, decrease of sexual function and increased hypersensitivity to pancreatic juice]. PMID- 4200754 TI - [Preliminary report on the results of mass screening for cervix neoplasms at 15 hospitals in Peking]. PMID- 4200756 TI - [Preliminary report on sex determination by sex chromatin of trophocytes during early pregnancy]. PMID- 4200755 TI - [Analysis of the result of mass screening for cervix cancer in a Tientsin district]. PMID- 4200758 TI - [Electromyographic activity in acupuncture locations during "techi"]. PMID- 4200757 TI - [Clinical observation on the effect of perfusion of drugs through the internal iliac artery in cervix cancer]. PMID- 4200759 TI - [Roentgenologic study of aortitis. II. Chest x-ray and its clinical significance]. PMID- 4200760 TI - [Hereditary hemorrhagic telangiectasia]. PMID- 4200761 TI - [Complications in reimplantation of severed limbs and their management]. PMID- 4200762 TI - [Amniotic fluid embolism]. PMID- 4200763 TI - [Treatment of intussusception in children: report of 23 cases]. PMID- 4200764 TI - [Clinical application of prostaglandin in obstetrics]. PMID- 4200765 TI - [Application of mathematical principles in medicine and public health]. PMID- 4200766 TI - Determination of gold in drugs and serum by use of anodic stripping voltammetry. PMID- 4200767 TI - Relationships among urinary aminoimidazolecarboxamide in urine and folate, and vitamin B12 concentrations in serum. PMID- 4200768 TI - A simplified determination of urinary cadmium, lead, and thallium, with use of carbon rod atomization and atomic absorption spectrophotometry. PMID- 4200769 TI - Gametocytocidal and sporontocidal effects of antimalarial drugs on malaria parasites. I. Effect of single and multiple doses of primaquine on Plasmodium cynomolgi. PMID- 4200770 TI - Theileria lawrencei: infection in the Indian water buffalo, Bubalus bubalis. PMID- 4200771 TI - Ileal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) and disodium dichloromethylene diphosphonate(C12 MDP) in the chick. PMID- 4200772 TI - N-Carbobenzoxy-L-pyroglutamyl-L-hitidyl peptides. PMID- 4200773 TI - Carbonic anhydrase activity in Rana pipiens skin: biochemical and histochemical analysis. PMID- 4200774 TI - Ultracentrifugal and immunological comparisons of succinylated human thyroglobulin and 27 S iodoprotein. PMID- 4200775 TI - Release of endotoxin in the form of cell wall blebs during in vitro growth of Neisseria meningitidis. AB - Multiple cell wall blebs were observed on the surface of three strains of N. meningitidis taken from log phase cultures. The blebs originated as evaginations of the outer layer of the cell wall. Bleb production was noted on both defined or complex media either as broth or a solid medium. The addition of 10% normal bovine serum to the various media did not affect the production and release of these surface blebs. However, as broth cultures progressed into the stationary phase of growth, the blebs disappeared from the surface of the cells. Blebs were present in substantial quantities in culture supernatant fluids and on cell surfaces and were readily isolated by ultracentrifugation. Analysis for 2-keto-3 deoxyoctonate in cultures revealed that 18% of the total endotoxin of log phase cultures was present in blebs from the cell wall. PMID- 4200776 TI - Interaction of human thymus-derived and non-thymus-derived lymphocytes in vitro. Induction of proliferation and antibody synthesis in B lymphocytes by a soluble factor released from antigen-stimulated T lymphocytes. AB - Relatively pure populations of human T and B lymphocytes were obtained from blood and tonsils using density gradient centrifugation in bovine serum albumin. Antigen alone was incapable of triggering the B lymphocyte into blast transformation or to secrete antibody. However, supernatants from tetanus toxoid stimulated T cells obtained from immune donors contained a factor mitogenic for B lymphocytes. 50-60% of B cells responded to this lymphocyte mitogenic factor (LMF) by proliferation, loss of C3 reactivity, and change to a secretory state. LMF-stimulated B cells exhibited a three- to fivefold increase in protein secretion and a six- to eightfold increase in gamma G globulin secretion. De novo secreted IgG had specificity directed to the tetanus toxoid present in the LMF containing T-cell supernatants. This was confirmed by an increase in the number of indirect plaque-forming cells to tetanus toxoid-coated sheep red blood cells after stimulation of B cells with LMF. It is proposed that in the course of the response to a previously encountered protein antigen, sensitized human T cells emit a signal in the form of a soluble product that, together with antigen, triggers B cells into division and antibody secretion. The experimental model utilized can be adapted to study human T-B cell cooperation under various conditions in normal individuals and in individuals with immunodeficiency diseases. PMID- 4200777 TI - Idiotypic specificity of rabbit antibodies to streptococcal group polysaccharides. AB - Anti-idiotypic antisera against six restricted rabbit streptococcal group specific antibodies have been raised in rabbits matched for allotypes. All these antisera reacted specifically with their homologous idiotypes on double-diffusion tests in agarose gel. In addition, they showed a high incidence of cross specificities with group-specific hyperimmune sera induced in both closely related and unrelated individuals. These precipitating cross-specificities could be explained for two systems by the interference of rheumatoid factor. Two idiotypic antibody systems have been analyzed in detail; these were restricted antibodies produced in a father and in one of his offspring. The methods employed included binding inhibition of radio-labeled homologous Fab fragments and hemagglutination inhibition with homologous idiotypic coat. The data demonstrated that only related rabbits produced, besides non-cross-reacting antibodies, idiotypically similar antibodies raised to the same antigen. About one-third of the cross-reactive idiotypes showed binding inhibition between 31 and 92%. Inhibition of binding above 50% in the paternal idiotypic system was only achieved by one offspring antibody whereas the F(1) progeny idiotypic system was inhibited to this extent by seven antibodies of related rabbits. In contrast, 87.5% and 91.7% of antibodies of unrelated rabbits were less than 20% inhibitory. Within this study two idiotypically identical antibodies have not been found. This implies that A-variant-specific antibodies of related rabbits which produced antipolysaccharide antibodies were structurally different. Cross-reaction, even if greater than 90% by binding inhibition, appears to involve only part and not all of the variable regions. PMID- 4200779 TI - Failure to demonstrate a humoral immune response to scrapie infection in mice. PMID- 4200778 TI - An electrophoretic difference between surface and secreted IgM of murine splenocytes. AB - micro-chains on the surface of murine splenocytes are more heterogeneous on SDS polyacrylamide gel electrophoresis than both secreted and intracellular micro chains labeled with [(3)H]tyrosine. No difference in heterogeneity among cell surface, secreted, or intracellular L chains was detected. The possible role of carbohydrate in micro-chain heterogeneity is discussed. PMID- 4200780 TI - An effector-cell independent step in target cell lysis by sensitized mouse lymphocytes. PMID- 4200781 TI - An agglutination-flocculation test for rapid detection of hepatitis B antigen. PMID- 4200783 TI - Communication skills in five-year-old children with high-risk neonatal histories. PMID- 4200782 TI - Identification of J-chain in polymeric immunoglobulins from a variety of species by cross-reaction with rabbit antisera to human J-chain. PMID- 4200784 TI - The health and nutritional status of children in Tabora region, Tanzania. PMID- 4200785 TI - The fate of the hospitalized malnourished child in Iran. PMID- 4200786 TI - The operation and function of malwards in the Philippines. PMID- 4200787 TI - A rural nutrition rehabilitation project at Kasangati health centre. PMID- 4200788 TI - [Occupational lead poisoning from the viewpoint of internal medicine]. PMID- 4200789 TI - [Cardiovascular xanthomatosis in childhood with primary hyperlipoproteinemia type II]. PMID- 4200790 TI - [Acute esophagitis due to photon irradiations and antineoplastic agents. Clinical, functional and therapeutic aspects]. PMID- 4200791 TI - [On a case of chronic paratyphoid B]. PMID- 4200794 TI - Mitosis in the Crypyophyvrsr. PMID- 4200792 TI - Ancient linkage groups and frozen accidents. PMID- 4200795 TI - The psychiatric nurse as therapist. 3. Operant treatment of the long-term patient. PMID- 4200796 TI - An automatic film densitometer and some applications in the field of radiotherapy. PMID- 4200798 TI - HL-A reagents from primates. I. Antigen preparation, immunization, and preliminary analysis of sera. PMID- 4200797 TI - [Particular aspect of frontal evoked visual responses in Papie papie]. PMID- 4200799 TI - Granulocyte alkaline phosphatase activity: a measure of the emergence time of mature marrow neutrophils? PMID- 4200800 TI - The treatment of terminal metamorphosis of chronic granulocytic leukaemia with corticosteroids and vincristine. PMID- 4200801 TI - Spontaneous platelet aggregation in myeloproliferative disorders. A preliminary study. PMID- 4200803 TI - Glucose-6-phosphate dehydrogenase electrophoresis in Ghanaians with AA and SS haemoglobin. PMID- 4200802 TI - A comparison of the three in vivo assays for haemopoietic stem cells. PMID- 4200804 TI - Haemoglobin c in arabs in kuwait. PMID- 4200805 TI - Congenital thrombocytopathy (platelet factor 3 defect) with prolonged bleeding time but normal platelet adhesiveness and aggregation. PMID- 4200806 TI - Hereditary persistence of fetal hemoglobin and beta-thalassemia in a Turkish child. PMID- 4200807 TI - The levodopa test of growth hormone reserve in children. PMID- 4200808 TI - Meningococcal meningitis following rifampin prophylaxis. PMID- 4200809 TI - Congenital diverticulum of the left ventricle. PMID- 4200810 TI - Physiologic and pathologic profiles of circulating human prolactin. PMID- 4200811 TI - Onset of espundia after many years of occult infection with Leishmania braziliensis. PMID- 4200812 TI - Pathology of the testis and epididymis in the late phase of experimental Chagas's disease. PMID- 4200814 TI - Further observations on the primary paranasal aspergillus granuloma in the Sudan: a morphological study of 46 cases. PMID- 4200813 TI - Immunization with a zoophilic strain of Schistosoma japonicum: a re-evaluation of the Formosan strain of S. japonicum in rhesus monkeys. PMID- 4200815 TI - Exogenous reinfection with Mycobacterium tuberculosis confirmed by phage typing. PMID- 4200816 TI - Experimental pulmonary edema following re-expansion of pneumothorax. PMID- 4200817 TI - Miliary tuberculosis in a renal transplant recipient. PMID- 4200818 TI - Background factors for casual isolation of Mycobacterium intracellulare from sputum of patients with tuberculosis. PMID- 4200819 TI - L-asparaginase activity in mycobacteria. PMID- 4200820 TI - Effect of age on the enzymes of tricarboxylic acid and related cycles in Mycobacterium tuberculosis H37Rv. PMID- 4200821 TI - Effects of cord factor on pyrazinamide deamidase. PMID- 4200823 TI - Letter: Susceptibility tests and initial and primary drug resistance in tuberculosis. PMID- 4200822 TI - Fractionation of antigenic components of histoplasmin by disc electrophoresis. PMID- 4200824 TI - Letter: Infection with Mycobacterium avium in monkeys. PMID- 4200826 TI - Letter: Neurofibroma and nevoid basal cell carcinoma. PMID- 4200825 TI - Endemic superficial pyoderma in children. PMID- 4200827 TI - Jugular vein compression and elevation of perilymphatic fluid pressure. PMID- 4200828 TI - Biochemical studies of the chromaffin granule. 3. Redistribution of lipid phosphate, dopamine-beta-hydroxylase and chromogranin A after freezing and thawing of the isolated granule membranes. PMID- 4200829 TI - Relevance of antigenicity of Candida albicans growth phases to diagnosis of systemic candidiasis. AB - The antigenicity of the two growth phases of Candida albicans has been compared by using crossed immunoelectrophoresis and double-diffusion techniques. Qualitative and quantitative differences in antigenic composition between the phases have been revealed and moreover a specific mycelial antigenic component demonstrated.It is postulated that the use of specific mycelial antigens for routine diagnostic precipitin testing in patients with suspected systemic candidiasis would give more reliable results than at present obtained with yeast cell antigens. PMID- 4200830 TI - The levels of superoxide dismutase and catalase in human tissues as determined immunochemically. PMID- 4200831 TI - Freeze-injury in bacteria. PMID- 4200832 TI - Properties of two growth-stimulating proteins isolated from fetal calf serum. PMID- 4200833 TI - Gliding motility of algae in unaffected by cytochalasin B. PMID- 4200834 TI - [Sensitivity of ova of Drosophila (Drosophila melanogaster Meig.) to the lethal action of ultraviolet rays. 3. Repair of lesions]. PMID- 4200835 TI - Letter: Further evidence for a role of H202 in radiation sensitization of bacterial spores. PMID- 4200836 TI - Influence of high-protein diets on renal function. PMID- 4200837 TI - Resistance of Escherichia coli to penicillins: identification of the structural gene for the chromosomal penicillinase. AB - A screening procedure was used to isolate a number of mutants of Escherichia coli K-12 with low penicillinase activity. By co-transduction with purA, three of the mutants were found to map near 82 min. Penicillinase was purified from one mutant and from a transductant with a temperature-sensitive enzyme. Comparison with wild type penicillinase revealed similarities in the Ouchterlony immunodiffusion test but differences in the catalytic properties. It is concluded that the mutations have occurred in the structural gene of the chromosomal penicillinase (designated ampC). Purified enzyme and a temperature-sensitive mutant were used to investigate whether the penicillinase has a physiological function related to biosynthesis or breakdown of murein. No positive evidence for any such function was obtained. PMID- 4200838 TI - Initiation of deoxyribonucleic acid replication in a temperature-sensitive mutant of B. subtilis: evidence for a transcriptional step. AB - A mutant of Bacillus subtilis unable to initiate a new round of replication at 45 C has been described. Here we show that inhibition of DNA synthesis in this mutant is reversible and that DNA synthesis is resumed at low temperature, even in the presence of chloramphenicol. Initiation of a new replication cycle thus can occur in the absence of protein synthesis. A thermolabile component required for initiation therefore appears to be synthesized at 45 C in an inactive form and can be activated at 30 C in the presence of an inhibitor of protein synthesis. Although resistant to chloramphenicol, the reinitiation of replication occurring after lowering the temperature is sensitive to rifampin and streptolydigin. PMID- 4200839 TI - Conditions affecting the isolation from transformed cells of Bacillus subtilis of high-molecular-weight single-stranded deoxyribonucleic acid of donor origin. AB - The deoxyribonucleic acid (DNA) extraction procedure of Piechowska and Fox was evaluated to determine which steps are required for the isolation of high molecular-weight single-stranded material from transformed cultures of Bacillus subtilis. The results indicate that high-molecular-weight single-stranded DNA can be isolated when certain basic proteins are present at the time of lysis. In the absence of such protective agents as lysozyme or cytC the single-stranded DNA is degraded. The single-stranded DNA can also be protected by being treated with lysozyme at low temperature. The high molecular weight of this single-stranded material and its kinetics of appearance are consistent with its being an intermediate in the transformation process. PMID- 4200841 TI - Appearance of a ribonucleic acid polymerase-binding protein in asporogenous mutants of Bacillus subtilis. AB - A 70,000-dalton protein that is found in sporulating Bacillus subtilis and that binds to ribonucleic acid polymerase is present in asporogenous mutants that proceed to or beyond stage II of sporulation, but is absent from mutants blocked at stage zero. PMID- 4200840 TI - Kinetic analysis of the products of donor deoxyribonucleate in transformed cells of Bacillus subtilis. AB - This paper describes the major transmutations of donor deoxyribonucleic acid (DNA) after uptake by competent Bacillus subtilis cells. Kinetic experiments confirm that after exposure to competent cells, donor DNA is converted to double stranded fragments (DSF) which can be isolated as early as 30 s from the beginning of the reaction. At this time, DSF represent the only identifiable product of donor origin. After 1 to 2 min, DSF are converted to deoxyribonuclease resistant forms, identified as single-stranded DNA fragments (SSF). SSF are intermediates in the transformation process leading to the formation of donor recipient complex. This component makes its appearance between 2 to 4 min from the beginning of the transformation process. All the donor-recipient complexes found at the end of the reaction can be accounted for quantitatively by the DSF and the SSF found in the initial stages of transformation. A quantitative discussion of the transformation process is included. PMID- 4200843 TI - Phycobilisomes from a blue-green alga Nostoc species. AB - Phycobilisomes were isolated from a Nostoc sp. strain Mac in phosphate buffer (pH 7.0) by treatment with 1% Brij 56 and centrifugation on discontinuous sucrose gradients (2.0, 1.0, 0.5, and 0.25 M in the proportions 6:4:4:10 ml, respectively). Absorption spectra of isolated phycobilisomes showed the presence of phycoerythrin, phycocyanin, and allophycocyanin. The phycobilisome pigments were partially resolved by electrophoresis on acrylamide gels. Stained gels demonstrated that each main protein band corresponded to a pigmented region. The phycobilisomes appeared compact with a rounded surface and flattened base (about 40-nm diameter) at the attachment site to the photosynthetic lamellae. Fixation in glutaraldehyde caused a significant reduction in total pigment absorption, as well as shifts in the absorption maxima, particularly that of phycoerythrin. PMID- 4200842 TI - NH2-terminal amino acid distribution and amino acid composition of Streptococcus faecalis R soluble and ribosomal proteins. AB - The NH(2)-terminal amino acid distribution of Streptococcus faecalis R soluble and ribosomal proteins isolated from cells at different stages of growth on either folate-sufficient or folate-deficient medium was determined by the dinitrophenyl method. The NH(2)-terminal residues do not follow the random distribution observed for the total amino acid composition of S. faecalis soluble and ribosomal proteins. Methionine and alanine occur most frequently; serine, threonine, aspartic and glutamic acids, and glycine are also present at the NH(2) terminal position of S. faecalis R proteins. The absence of folic acid yields cells that are incapable of formylating methionyl-transfer ribonucelic acid tRNA(f) (Met), but does not affect either the qualitative or quantitative NH(2) terminal distribution of total soluble or total ribosomal proteins compared to cells grown with folate. A small quantitative difference was observed in the frequency of distribution of certain amino acids at the NH(2)-termini between log and stationary phase soluble proteins. The amino acid residues found at the NH(2) terminal position of S. faecalis proteins are qualitatively similar to those reported for several other organisms. PMID- 4200846 TI - Relationship between transformation in Bacillus subtilis and infection by bacteriophage SP02. AB - When bacteriophage SP02 infects a Bacillus subtilis culture during or shortly after transformation, the frequency of transformants among the resulting lysogens is greatly reduced relative to that in the uninfected culture. The effect can occur after the deoxyribonucleic acid has been taken up and covalently attached to recipient deoxyribonucleic acid. PMID- 4200845 TI - Mode of action of glycine on the biosynthesis of peptidoglycan. AB - The mechanism of glycine action in growth inhibition was studied on eight different species of bacteria of various genera representing the four most common peptidoglycan types. To inhibit the growth of the different organisms to 80%, glycine concentrations from 0.05 to 1.33 M had to be applied. The inhibited cells showed morphological aberrations. It has been demonstrated that glycine is incorporated into the nucleotide-activated peptidoglycan precursors. The amount of incorporated glycine was equivalent to the decrease in the amount of alanine. With one exception glycine is also incorporated into the peptidoglycan. Studies on the primary structure of both the peptidoglycan precursors and the corresponding peptidoglycan have revealed that glycine can replace l-alanine in position 1 and d-alanine residues in positions 4 and 5 of the peptide subunit. Replacement of l-alanine in position 1 of the peptide subunit together with an accumulation of uridine diphosphate-muramic acid (UDP-MurNAc), indicating an inhibition of the UDP-MurNAc:l-Ala ligase, has been found in three bacteria (Staphylococcus aureus, Lactobacillus cellobiosus and L. plantarum). However, discrimination against precursors with glycine in position 1 in peptidoglycan synthesis has been observed only in S. aureus. Replacement of d-alanine residues was most common. It occurred in the peptidoglycan with one exception in all strains studied. In Corynebacterium sp., C. callunae, L. plantarum, and L. cellobiosus most of the d-alanine replacing glycine occurs C-terminal in position 4, and in C. insidiosum and S. aureus glycine is found C-terminal in position 5. It is suggested that the modified peptidoglycan precursors are accumulated by being poor substrates for some of the enzymes involved in peptidoglycan synthesis. Two mechanisms leading to a more loosely cross-linked peptidoglycan and to morphological changes of the cells are considered. First, the accumulation of glycine-containing precursors may lead to a disrupture of the normal balance between peptidoglycan synthesis and controlled enzymatic hydrolysis during growth. Second, the modified glycine-containing precursors may be incorporated. Since these are poor substrates in the transpeptidation reaction, a high percentage of muropeptides remains uncross-linked. The second mechanism may be the more significant in most cases. PMID- 4200844 TI - Gene-enzyme relationships of aromatic acid biosynthesis in Bacillus subtilis. AB - Mutants have been isolated which correspond to every step concerned with the biosynthesis of the aromatic amino acids in Bacillus subtilis. Each mutant has been characterized, and the lesion it bore was analyzed by deoxyribonucleic acid transformation and PBS-1 mediated transduction. The biochemical analysis revealed that each of the mutations appears to have affected a single enzyme, except for two groups of pleiotropic mutations. All aroF mutants (chorismic acid synthetase) lack dehydroquinic acid synthetase (aroB) activity. The gene that specifies aroB is closely linked to the gene coding for the aroF enzyme. Both genes are a part of the aro cluster. Mutants lacking chorismate mutase activity also lack d arabino-heptulosonic acid-7-phosphate synthetase and shikimate kinase activity, presumably as a result of these three activities forming a multi-enzyme complex. Another mutant, previously undescribed, had been isolated. The affected gene codes for the tyrosine and phenylalanine aminotransferase activity. All of the mutations have been located on the B. subtilis genome except those in the genes specifying shikimate kinase activity and tyrosine-phenylalanine aminotransferase activity. PMID- 4200847 TI - Effect of low-intensity light on growth response and bacteriochlorophyll concentration in Rhodospirillum rubrum mutant C. AB - Photosynthesizing cells of Rhodospirillum rubrum mutant C underwent adaptation for growth in low-light conditions. During adaptation there was a transitory increase in the generation time and the bacteriochlorophyll a content of the cells. PMID- 4200848 TI - Accumulation of messenger ribonucleic acid specific for extracellular protease in Bacillus subtilis 168. AB - Production of extracellular protease by Bacillus subtilis 168 in a medium containing low concentrations of amino acids is essentially linear, whereas in a medium containing high levels of amino acids the time course of production is biphasic. Cells harvested from the growth medium are capable of secreting enzyme for 30 min in the presence of rifampin, but the appearance of the enzyme is sensitive to chloramphenicol and pactamycin. The protease messenger ribonucleic acid (mRNA), nevertheless, appears to have a short half-life typical of bacterial messengers, and this indicates that these cells contain a relatively large pool of protease-specific mRNA. This pattern of results is identical to that observed previously with B. amyloliquefaciens. Because it has now been found in two distinct organisms, it is concluded that the accumulation of mRNA for extracellular protease, supported by rapid transcription, is a biologically meaningful phenomenon related to extracellular enzyme synthesis rather than aberrant behavior due to a transcriptional control mutation. PMID- 4200849 TI - Effect of isoleucine, valine, or leucine starvation on the potential for formation of the branched-chain amino acid biosynthetic enzymes. AB - The derepression of the isoleucine and valine biosynthetic enzymes in Escherichia coli and Salmonella typhimurium was examined under conditions of restriction of isoleucine, valine, or leucine (the three amino acids needed for multivalent repression of these enzymes). A procedure was used that allowed the measurement of enzyme-forming potential that accumulated during the starvation period, but could not be expressed unless the missing amino acid was supplied. The threonine deaminase (the product of the ilvA gene)-forming potential that accumulated under such conditions was found to be unstable and decayed with a half-life of about 2.5 min (at 37 C). Evidence was obtained that indicates the threonine deaminase forming potential that accumulates under conditions of isoleucine starvation is in the form of initiated (rifampin-resistant), but uncompleted (actinomycin D sensitive), messenger ribonucleic acid chains. Furthermore, it appears that a large portion of the threonine deaminase- and dehydrase (the product of the ilvD gene)-forming potential, under such conditions, is in the form of initiated polypeptide chains. Based on these results and results obtained with SuA(-) strains, a model is presented that explains how the second gene (D) in the ilvADE operon can be partially transcribed and translated under conditions in which there are no completed messenger ribonucleic acids for the gene (A) transcribed before it. PMID- 4200850 TI - Genetics and biochemistry of pyrimidine biosynthesis in Bacillus subtilis: linkage between mutations resulting in a requirement for uracil. AB - A number of independently derived uracil-requiring mutant strains of the parent strain 168 were mapped by inter-mutant transformation crosses. Only a few of these mutant strains were found to be transformable. Studies were performed in which these transformable uracil-requiring mutant strains were used as the recipient of deoxyribonucleic acid extracted from phenotypically similar mutant strains. The results yielded data resulting in a fine-structure map in which all mutations were found to be linked in a small region corresponding to that previously published as the uracil region of the Bacillus subtilis genome. PMID- 4200851 TI - Ribonucleic acid polymerase in a thermosensitive sporulation mutant (ts-4) of Bacillus subtilis. AB - Partially synchronized cultures of a Bacillus subtilis thermosensitive sporulation mutant (ts-4) and the 168 try(-)try(-) (168tt) parental strain were infected with the virulent phage phie at various times during their growth cycle at 30 and 42 C (permissive and restrictive temperatures, respectively). It was shown that at the restrictive temperature the burst size in the parental strain was two- to threefold lower than in the ts-4 mutant. No such difference was observed at the permissive temperature. However, the time at which this difference was observed excludes a correlation between the burst size and initiation of the sporulation process. It was further found that the capacity to transcribe in vitro phage phie deoxyribonucleic acid by partially purified ribonucleic acid (RNA) polymerase from both strains decreased sharply if the source of enzyme was sporulating cells instead of vegetative ones. However, a similar decrease, although to a lesser extent, was observed with the RNA polymerase isolated from stationary-phase cells of the ts-4 mutant grown at the nonpermissive temperature, or with the enzyme derived from several other zero stage sporulation mutants. At no time was a structural modification in the beta subunits of the RNA polymerase observed during growth of the sporulating bacteria. We have also shown that, in addition to the relatively low specific activity of the RNA polymerase, the level of the intracellular protease activity is about 15-fold lower in the ts-4 mutant grown at the restrictive temperature than that of the parental strain grown at the same temperature. At the permissive temperature no such difference was observed between these two strains. However, the present data do not allow us to establish a correlation among the low content of intracellular protease, the weak specific activity of the RNA polymerase, and the loss of the sporulation capacity in the ts-4 mutant grown at the restrictive temperature. PMID- 4200852 TI - Enzymes of the tryptophan pathway in three Bacillus species. AB - The tryptophan synthetic pathway was characterized in three species of Bacillus, B. subtilis, B. pumilus, and B. alvei. They share the common features of a pathway which is subject to tryptophan repression, contains no unexpected complexes among the five enzymes, exhibits dissociable anthranilate synthase enzymes which do not require phosphoribosyl transferase for amidetransfer activity, contains separate indoleglycerol phosphate synthase and phosphoribosylanthranilate isomerase enzymes, and contains similar tryptophan synthetase multimers. In looking at these characteristics in detail however, differences among the three species became apparent, as, for example, in the complementation observed between the alpha and beta(2) components of tryptophan synthetase, and the dissociation patterns of the large and small components of anthranilate synthase. The results demonstrate some pitfalls in attempting to compare multimeric enzymes in crude extracts from different organisms. PMID- 4200853 TI - Genetic studies of leucine biosynthesis in Bacillus subtilis. AB - The mutations in a series of leucine auxotrophs isolated after treatment with nitrosoguanidine, ultraviolet light, and ICR-191 have been mapped between ilvC and pheA on the Bacillus subtilis chromosome. A fine structure map of the region was constructed by transformation. Analysis of several strains by assaying levels of their leucine bioysnthetic enzymes has shown that the region encodes three enzymes. The order of the genes with respect to the biosynthetic steps catalyzed by the gene products is 1-3-2. PMID- 4200855 TI - Synchronous cultures of Bacillus subtilis obtained by filtration with glass fiber filters. AB - A simple method of potentially wide applicability for obtaining synchronous cultures of Bacillus subtilis based on size selection is described. Using glass fiber filters, a population (about 1 to 2% of the parent population) can be obtained substantially enriched for small cells which grow synchronously. A method for rapidly concentrating dilute suspensions of cells is described. PMID- 4200854 TI - Regulation of leucine biosynthesis in Bacillus subtilis. AB - The biosynthesis of alpha-isopropylmalate (alphaIPM) synthetase, IPM isomerase, and betaIPM dehydrogenase in Bacillus subtilis can be derepressed in leucine auxotrophs by limiting them for leucine. The derepression of the three enzymes is apparently coordinate. A class of mutants resistant to 4-azaleucine excretes leucine and has derepressed levels of all three enzymes. The azaleucine resistance mutations may lie in a gene (azlA) encoding a repressor. Efforts to find mutations characteristic of a constitutive operator have been unsuccessful. No polar mutations have been found among nine leucine auxotrophs that have characteristics of frameshift mutations. The enzyme catalyzing the first step in leucine biosynthesis, alphaIPM synthetase, is sensitive to feedback inhibition by leucine. We conclude that leucine biosynthesis is controlled by the inhibition of the activity of the first biosynthetic enzyme by leucine, and by the repression of the synthesis of the first three biosynthetic enzymes by leucine. The repression of the three enzymes may be under the control of a single repressor and a single operator, or of a single repressor and a separate operator for each structural gene. PMID- 4200856 TI - Defined physiological conditions for the induction of the L-form of Neisseria gonorrhoeae. AB - Defined conditions are described which allowed luxuriant growth over continuous subculture of strains of Neisseria gonorrhoeae in broth and on agar. Growth was equal to or surpassed that observed in Mueller-Hinton broth or on Mueller-Hinton blood agar. The final medium adopted consisted of medium 199 and a supplemental mixture of cysteine, glucose, and various salts. Addition of sodium bicarbonate or CO(2) enrichment was not required. For solidification, only agarose allowed growth of all strains; glutamic acid stimulated growth of two strains but was inhibitory for a third. The addition of 8% polyvinylpyrrolidone (PVP), 2% purified albumin, and penicillin resulted in induction of all three strains to the L-form with frequencies up to 0.3%. At present no induction to the L-form has been achieved in the absence of albumin. Various lots of PVP proved toxic in the defined medium, and extensive dialysis was required for good growth and L-form induction. Substitution of PVP with sucrose indicated a sucrose toxicity for the parental gonococcus even on the addition of albumin. L-form induction did occur on sucrose L-medium but at significantly lower frequencies. The colonies appeared 1 week later than those on PVP L-medium but at significantly lower frequencies. The colonies appeared 1 week later than those on PVP L-medium and remained very small and poorly developed. PMID- 4200857 TI - Germination of Bacillus megaterium spores after various extraction procedures. AB - The initiation of germination of Bacillus megaterium QM B1551 spores, grown in supplemented nutrient broth, has been studied. The initiation properties depend on buffer concentrations and the particular batch of spores. Initiation in l alanine, KBr, calcium dipicolinate, or in buffer alone increases as a function of the spore age; whereas initiation in glucose, l-leucine, or l-proline remains relatively constant. Extraction of spores with alkali, sodium dodecyl sulfate dithiothreitol, or lithium diiodosalicylate removes variable amounts of dipicolinic acid, hexosamine, and protein. These extracted spores are still capable of initiation and, in some cases, initiation is stimulated. However, extraction of spores with 8 M urea-10% mercaptoethanol inhibits subsequent initiation. PMID- 4200858 TI - Development of ultraviolet resistance in sporulating Bacillus cereus T. AB - Ultraviolet (UV) resistance patterns of sporulating Bacillus cereus were determined. Six different categories of UV resistance were discernible as the organism progressed from exponential growth to the free, mature spore. Light microscope observations allowed the assignment of certain sporulation stages to specific UV resistance categories. Marked changes in UV resistance were associated with stages III, mid-IV, and post-IV of sporulation. Dipicolinic acid was shown to sensitize forespores to UV radiation. Mechanisms invoked to explain the different UV categories are discussed. PMID- 4200859 TI - Growth properties of Rhodospirillum rubrum mutants and fermentation of pyruvate in anaerobic, dart conditions. AB - Mutant C and G1 were obtained earlier from Rhodospirillum rubrum S(1) during growth in the dark under strict anaerobic conditions in medium containing sodium pyruvate. Mutant C and mutant G1 grew in the dark with generation times of 5.8 h and 4.6 h, respectively. Mutant C cells grew equally well when switched between anaerobic (dark or light) or aerobic, dark conditions. Mutant G1 cells grew only in the dark (anaerobic or aerobic conditions), but a fraction of cells in anaerobic, dark cultures grew when placed in light. This number increased about 3,000-fold when G1 cells were incubated aerobically in the dark. During anaerobic, dark growth, C and G1 organisms incorporated similar amounts of [2 (14)C]sodium pyruvate. About 34% of the incorporated radioactivity was found in lipid fractions from C cells that developed chromatophores during dark growth. Similar results were obtained using G1 cells, which formed only trace amounts of photosynthetic structures. Both mutants fermented sodium pyruvate and produced acetate, formate, carbon dioxide, and hydrogen gas. Molar growth yield coefficients indicated that the cells obtained about 1 mol of adenosine triphosphate per mol of sodium pyruvate fermented. Results suggested that pyruvate fermentation during dark growth occurred via a pyruvate formate-lyase or the pyruvate ferredoxin-oxidoreductase pathway, or both. PMID- 4200860 TI - Production and characterization of the slime polysaccharide of Pseudomonas aeruginosa. AB - The slime polysaccharides produced by Pseudomonas aeruginosa isolated from a variety of human infections were investigated. Slime production in culture seemed optimal when adequate amounts of carbohydrate were present and under conditions of either high osmotic pressure or inadequate protein supply. The polysaccharides produced by the organisms were similar to each other, to the slime of Azotobacter vinelandii, and to seaweed alginic acids. They were composed of beta-1,4-linked d mannuronic acid residues and variable amounts of its 5-epimer l-guluronic acid. All bacterial polymers contained o-acetyl groups which are absent in the alginates. The polysaccharides differed considerably in the ratio of mannuronic to guluronic acid content and in the number of o-acetyl groups. The particular composition of the slime was not found to be characteristic for the disease process from which the mucoid variants of P. aeruginosa were obtained. PMID- 4200861 TI - Effects of leucine starvation on control of ribonucleic acid synthesis in strains of Bacillus subtilis differing in deoxyribonucleic acid regulation. AB - When starved for leucine, strains of Bacillus subtilis do not complete chromosome replication to the terminus. The amount of deoxyribonucleic acid (DNA) made poststarvation is characteristic of the strain. In this study, four strains differing in their DNA response were examined for ribonucleic acid (RNA) regulation during leucine starvation. Each of the strains was judged to be stringent for RNA control based on the amount of RNA made poststarvation. Sucrose gradient profiles on RNA made with and without leucine starvation support this conclusion. Accumulation of guanosine tetraphosphate during leucine starvation showed no correlation with the amount of DNA synthesized. We concluded that modulation control of DNA synthesis during leucine starvation is independent of RNA control. PMID- 4200862 TI - New method for the isolation of membranes from Mycoplasma gallisepticum. AB - Mycoplasma gallisepticum lysed readily in carbonate bicarbonate buffer at pH 9.2 to 10.5. The hemagglutination titer of the lysates was 2- to 16-fold greater than a cell suspension at the same protein concentration in buffered saline. Membranes prepared from cells lysed by this method at pH 10 were relatively free from cytoplasmic contaminants as shown by electron microscopy of thin sections. The membranes retained their hemagglutination activity, gave reactions in immunodiffusion tests identical to those obtained by osmotic lysis and sonic treatment, and showed a similar pattern of protein bands by polyacrylamide disk electrophoresis. When inoculated into rabbits, the membranes gave rise to antibodies active in growth-, metabolic- and hemagglutination-inhibition tests. On the average, membranes obtained by lysis at pH 10 contained 44% of the original cell protein. The method is simple, giving high yields of membranes, and may be adaptable to other mycoplasmas. PMID- 4200863 TI - Ascorbate oxidase. Further studies on the purification of the enzyme. PMID- 4200864 TI - D-alanine carboxypeptidase from Bacillus subtilis membranes. I. Purification and characterization. PMID- 4200865 TI - D-alanine carboxypeptidase from Bacillus subtilis membranes. II. Interaction with penicillins and cephalosporins. PMID- 4200866 TI - The biosynthesis of unsaturated fatty acids by bacilli. V. In vivo substrate specificities of fatty acid desaturases. PMID- 4200867 TI - Effect of diamide on growth of selected bacteria. PMID- 4200868 TI - Serum "beta 1A" levels in older humans. PMID- 4200870 TI - Gastrostomy in laryngology. PMID- 4200869 TI - Habitat selection in experimental populations of Drosophila melanogaster. PMID- 4200871 TI - Synthetic penicillins. Heterocyclic analogs of ampicillin. Structure-activity relationships. PMID- 4200873 TI - Effect of aspartame on phenylalanine metabolism in the monkey. PMID- 4200872 TI - Metabolism of aspartame in monkeys. PMID- 4200874 TI - Relationship of C-reactive protein in autologous plasma of cancer patients and choline phosphate in lymphocyte responses to phytohemagglutinin. PMID- 4200875 TI - Erythromycin therapy twice daily for streptococcal pharyngitis. Controlled comparison with erythromycin or penicillin phenoxymethyl four times daily or penicillin G benzathine. PMID- 4200877 TI - Accumulation of hepatic mitochondria in 2-methyl-4-dimethyl-aminoazobenzene fed rats as a result of decreased degradation. PMID- 4200876 TI - In vitro activity of carbenicillin against Pseudomonas using the disc diffusion method. PMID- 4200879 TI - Editorial: Get in there and replant. PMID- 4200878 TI - [Value of pneumoencephalographies in cerebral diseases in children]. PMID- 4200880 TI - Vasopressin and neurophysin: high concentrations in monkey hypophyseal portal blood. AB - Vasopressin and its binding protein, neurophysin, were measured by radioimmunoassay in the hypophyseal portal blood of monkeys after cannulation of individual long portal veins. Mean vasopressin concentrations (13,800 picograms per milliliter) in portal blood were more than 300 times as high as those in the systemic circulation (42 picograms per milliliter). Neurophysin concentration was approximately 25 times as high in portal as in systemic blood. By immunoperoxidase techniques, high concentrations of neurophysin were demonstrated around portal capillaries of the median eminence. These studies indicate direct secretion of vasopressin and neurophysin into the portal circulation; the quantities secreted during stress may be sufficient to exert significant effects on secretion of anterior pituitary hormone. PMID- 4200881 TI - Proteins induced in Bacillus subtilis infected with bacteriophage phi 29. PMID- 4200882 TI - Presence of antibodies to double-stranded RNA in sera of rabbits immunized with rice dwarf and maize rough dwarf viruses. PMID- 4200883 TI - Japanese encephalitis virus glycoproteins. PMID- 4200884 TI - Protein synthesis in Japanese encephalitis virus-infected cells. PMID- 4200885 TI - Serum LH during ovulatory and anovulatory menstrual cycles in macaques. PMID- 4200886 TI - A cross-species comparison of status in small established groups. PMID- 4200888 TI - Pharmacokinetics of 1-beta-D-arabinofuranosylcytosine (ARA-C) deamination in several species. PMID- 4200887 TI - Binding of silver sulfadiazine to the cellular components of Pseudomonas aeruginosa. PMID- 4200889 TI - Homoserine dehydrogenase of Rhodospirillum rubrum. Enzyme polymerization in the presence and absence of threonine. PMID- 4200890 TI - Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases. PMID- 4200891 TI - Lactate dehydrogenase isozymes. Turnover in rat heart, skeletal muscle, and liver. PMID- 4200892 TI - Effects of metals on the properties of hepatic microsomal uridine diphosphate glucuronyltransferase. PMID- 4200893 TI - Evolutionary stability of the histone genes of sea urchins. PMID- 4200894 TI - Quenching of protein fluorescence by oxygen. Detection of structural fluctuations in proteins on the nanosecond time scale. PMID- 4200895 TI - [Synthesis of delta-aminolevulinic acid and chlorophyll during illumination of etiolated Euglena gracilis]. PMID- 4200896 TI - Carbon monoxide production from hydroxocobalamin by bacteria. PMID- 4200897 TI - [Surgical treatment of carcinoma of the esophagus and gastric cardia: preliminary report on 1,230 cases]. PMID- 4200898 TI - [Combined Chinese and Western medicine in the treatment of pneumonia in children]. PMID- 4200899 TI - [From acupuncture therapy to acupuncture anesthesia]. PMID- 4200901 TI - [Acupuncture anesthesia in neurosurgery]. PMID- 4200900 TI - [New development in infectious hepatitis]. PMID- 4200902 TI - [Observations on analgesic effects of needling Chuanliao point in neurosurgery: report of 619 cases]. PMID- 4200903 TI - [Analysis of the effectiveness of acupuncture anesthesia in thyroidectomy]. PMID- 4200904 TI - [Studies on acupuncture anesthesia in laryngectomy]. PMID- 4200905 TI - [Clinical results of the use of acupuncture anesthesia in pulmonary resection]. PMID- 4200906 TI - [Acupuncture anesthesia in thoracic surgery: clinical analysis of 818 cases]. PMID- 4200907 TI - [Use of acupuncture anesthesia in cardiac surgery]. PMID- 4200908 TI - [Acupuncture anesthesia in splenectomy: report of 305 cases]. PMID- 4200909 TI - [Use of a acupuncture anesthesia in pediatric surgery: report of 1,308 cases]. PMID- 4200910 TI - [Auricular injection of physiological saline for anesthesia for tooth extraction: report of 1,250 cases]. PMID- 4200911 TI - [Preliminary observations on the use of acupuncture anesthesia in operations in shock and critial cases]. PMID- 4200912 TI - [Effect of acupuncture of the philtrum on hemorrhagic shock in cats]. PMID- 4200913 TI - Interrelation of the urinary trypsin inhibitor to human plasma inter-alpha trypsin inhibitor. PMID- 4200914 TI - The acyl-carrier protein of citrate lyase. PMID- 4200915 TI - On the reconstitution of photophosphorylation in chloroplast membranes. PMID- 4200916 TI - An unusual type of bacterial cell-wall in a mutant of Bacillus subtilis 168. PMID- 4200917 TI - Studies on the sensitization of animals with simple chemical compounds. XIV. Further studies on sensitization of guinea pigs with picric acid. PMID- 4200918 TI - Systemic and urinary immune response in experimental E. coli pyelonephritis of mice. PMID- 4200919 TI - Skin reactions induced by sera of patients with monoclonal IgG gammapathy. PMID- 4200921 TI - Sterilization of anesthesia apparatus. PMID- 4200920 TI - [Dysphagia caused by non-malignant esophageal diseases]. PMID- 4200922 TI - Glycosphingolipids of membrane fractions from normal and transplanted canine kidney. PMID- 4200923 TI - Deoxyribonucleic acid synthesis in bacteriophage SP01-infected Bacillus subtilis. II. Purification and catalytic properties of a deoxyribonucleic acid polymerase induced after infection. PMID- 4200924 TI - Proteolytic conversion of the molecular forms of bovine milk galactosyltransferase. PMID- 4200925 TI - Chromatographic behaviour of mouse spleen cells on glass bead columns. PMID- 4200926 TI - Effects of castration and replacement therapy on sexual behavior of adult male rhesuses. PMID- 4200927 TI - Avoidance learning in phenylketonuric monkeys. PMID- 4200928 TI - Visual sensitivity following inferotemporal and foveal prestriate lesions in the rhesus monkey. PMID- 4200929 TI - Pteridines. 2. New 6,7-disubstituted pteridines as potential antimalarial and antitumor agents. PMID- 4200930 TI - Metastable secondary structures in ribosomal RNA molecular hysteresis in the acid base titration of Escherichia coli ribosomal RNA. PMID- 4200931 TI - Effects of pollution on freshwater fish. PMID- 4200932 TI - [Immunoserological studies in the diagnosis of liver diseases]. PMID- 4200933 TI - Biologic aspects of endodontics. V. Periapical tissue reactions to root canal instrumentation beyond the apex and root canal fillings short of and beyond the apex. PMID- 4200934 TI - [Subtrigonal diverticle as a cause of acute urinary retention]. PMID- 4200936 TI - [Central venous pressure and other parameters in the evaluation of fluid balance in intensive care patients (author's transl)]. PMID- 4200935 TI - [Usefulness of plasma TSH determination and of the TRH test in thyroid pathology (author's transl)]. PMID- 4200937 TI - T3 thyrotoxicosis. PMID- 4200938 TI - Gout. PMID- 4200939 TI - Determination of revised Air Force permissible exposure levels for laser radiation. PMID- 4200940 TI - The cerebrospinal fluid in uncontrolled diabetes mellitus. PMID- 4200941 TI - [Comparative study of pulmonary artery and left ventricle diastolic pressures during the acute stage of myocardial infarction]. PMID- 4200942 TI - [Simultaneous measurement of cardiac output using thermal and dye dilution technics]. PMID- 4200943 TI - [Coronary arteriography in valvulopathies complicated by thoracic pain]. PMID- 4200944 TI - [Isolated obstructive thrombosis of the mitral valve]. PMID- 4200945 TI - [Precise localization of the sino-atrial node]. PMID- 4200946 TI - [Ordistim 70 data processing system for the surveillance of patients with pacemakers]. PMID- 4200947 TI - [Ventricular fibrillation during reestablishment of coronary artery circulation (clamp release fibrillation)]. PMID- 4200948 TI - [Study of systolic intervals in hyperthyroidism without cardiac complications]. PMID- 4200949 TI - [Renal hemodynamics and water-sodium excretion in experimental aortic insufficiency in rabbits]. PMID- 4200950 TI - [Calcified tricuspid endocarditis in infants]. PMID- 4200951 TI - [Apparently primary pericardial effusion in the newborn infant]. PMID- 4200952 TI - [A further case of ventricular tachycardia by reentry]. PMID- 4200953 TI - [A case of complete atrioventricular block caused by syphilitic gumma of the interventricular septum]. PMID- 4200954 TI - Bilateral meningococcal endophthalmitis. PMID- 4200955 TI - Immunologic studies of antihemophilic factor (AHF, factor VIII). V. Immunologic properties of AHF subunits produced by salt dissociation. PMID- 4200956 TI - Lymphocytes forming red cell rosettes in the cold in patients with chronic cold agglutinin disease. PMID- 4200957 TI - Patterns of new chronicity in a mental hospital. PMID- 4200958 TI - Editorial: Smallpox eradication. PMID- 4200960 TI - [Clinical and pathological correlation of coronary heart disease in the aged]. PMID- 4200959 TI - Indwelling catheter infection. AB - A "catheter team", consisting of two hospital assistants specially trained to catheterize male patients, inserted indwelling catheters in 435 men over a two year period. The infection rate was 33%; in the 200 patients not treated with antimicrobial drugs (study group) the rate was 37%, while in the 235 patients who were so treated (antibacterial group) the infection rate was 29%. Fifty percent of patients not treated were infected after 6.3 days, whereas in patients on antibacterial therapy a 50% infection rate was not reached until 14 days after insertion. Therefore, no antibacterial therapy is necessary if it is anticipated that the catheter will be necessary for less than four days. On the other hand, prophylactic antibacterial therapy would delay the onset of infection considerably if catheterization were expected to continue for more than four days. Sulfisoxazole was our drug of choice for prophylactic treatment. PMID- 4200961 TI - [Coronary arteriosclerosis: clinicopathological study]. PMID- 4200962 TI - [Experience in emergency management of acute myocardial infarct-analysis of 303 cases]. PMID- 4200963 TI - [Initial experience in application of a combination of Chinese and Western medicine to treat acute myocardial infarct]. PMID- 4200964 TI - [Preliminary experience in the experimental study of acute abdominal conditions treated with combination of Chinese and Western medicine]. PMID- 4200965 TI - [Developments in reimplantation of limbs and fingers]. PMID- 4200966 TI - [Xeroradiography]. PMID- 4200967 TI - [Preliminary report on animal experiments and clinical application of retinal laser coagulation]. PMID- 4200968 TI - [Roentgenologic study of aorto-arteritis. I. Analysis of angiography in 92 cases]. PMID- 4200969 TI - [Use of fibrous filtering membrane for sampling dust concentration and estimating dust dispersion]. PMID- 4200970 TI - [Quantitative study of major pollutants emitted from diesel engines]. PMID- 4200971 TI - [Report on the use of a portable gas-cooling ophthalmic cryo-coagulator]. PMID- 4200972 TI - [Clinical enzyme diagnosis in acute myocardial infarct]. PMID- 4200973 TI - [Biguanide therapy of obesity?]. PMID- 4200974 TI - Experimental infective pneumoconiosis: effect of asbestos dust and Candida albicans infection on the lungs of rhesus monkeys. PMID- 4200976 TI - Modulation of masseteric and digastric neural activity by stimulation of the dorsolateral cerebral cortex in the squirrel monkey. PMID- 4200975 TI - Function of adrenal gland-zona fasciculata in rats receiving polychlorinated biphenyls. PMID- 4200977 TI - Spinal and cortical inhibition of intestinal motility in the squirrel monkey. PMID- 4200978 TI - [Idiopathic acquired sideroblastic anemia]. PMID- 4200979 TI - [Behavior of lipids in the spleen and thymus gland in rats maintained on a low protein diet with and without choline]. PMID- 4200980 TI - [Case of acute erythremic myelosis]. PMID- 4200982 TI - [Chromosome study in a case of malignant reticulosis]. PMID- 4200981 TI - [Prolonged and repeated stimulation with PHA and lymphocyte blastic response in Hodgkin's disease]. PMID- 4200983 TI - [Evaluation of erythropoietic activity in syngeneic radio-chimeras]. PMID- 4200984 TI - [Amyloidosis. Clinical contribution]. PMID- 4200985 TI - [Quantitative method for determination of fibrinolytic agents released from tissue cultures]. PMID- 4200986 TI - A comparative study of isocyclic hydrocarbons in animals and in man. PMID- 4200988 TI - [Lipid composition of the blood platelets in the newborn infant]. PMID- 4200987 TI - [Study of the lipid composition of the blood platelets in 5 cases of thrombasthenia]. PMID- 4200990 TI - A comparison of chlorpromazine, imipramine, morphine and d-amphetamine self administration in cocaine-dependent rhesus monkeys. PMID- 4200989 TI - Disposition of clonixin (2-(3-chloro-o-toluidino) nicotinic acid) in humans. PMID- 4200992 TI - [Use of tube feeding through the small intestine in the surgical clinic]. PMID- 4200991 TI - Delayed repair of esophageal atresia with T-E fistula in two premature infants. Use of a jejunostomy as an alternative to intravenous alimentation. PMID- 4200993 TI - [Clinical and cytogenetic correlations in Turner's syndrome]. PMID- 4200994 TI - Embryo transfer and sensitivity to teratogenesis. PMID- 4200995 TI - Enhancement of metabolic coronary dilatation by aspirin-like substances by suppression of prostaglandin feedback control? PMID- 4200997 TI - Multivariate analysis of the Dryopithecus africanus forelimb. PMID- 4200996 TI - Further investigations into the teratogenic potential of imperfect potatoes. PMID- 4200998 TI - Intracranial mycotic aneurysms and subacute bacterial endocarditis in heroin addiction. PMID- 4200999 TI - Brain abscess from septic cerebral embolism: an experimental model. PMID- 4201000 TI - [Cardio-cutaneous syndromes of genetic origin]. PMID- 4201001 TI - Experience in the treatment of hepatic failure by intermittent liver hemoperfusions. PMID- 4201002 TI - Impaired function of polymorphonuclear leukocytes in patients with burns and other trauma. PMID- 4201003 TI - Experience with intensive surveillance of urinary tract infection. PMID- 4201004 TI - Triglyceride and free fatty acid clearances in patients receiving complete parenteral nutrition using a ten per cent soybean oil emulsion. PMID- 4201005 TI - Prevention of postoperative intestinal adhesions in primates. PMID- 4201006 TI - A kwashiorkor-like syndrome in hospitalized patients. PMID- 4201007 TI - Effect of treatment on the development of vascular lesions in the hypertensive rat. PMID- 4201008 TI - Undifferentiated mononuclear cell in human embryonic liver; presumptive hematopoietic stem cell. PMID- 4201009 TI - [Pseudofollicular nests of plasmacells (of a special type?) in paracortical pulp of human lymph nodes (author' s transl)]. PMID- 4201010 TI - Morphological modifications of the frog bladder induced by non ionic detergents (Rana pipiens L.). PMID- 4201011 TI - [Intracisternal tubular aggregates in cells of human fetuses with rubella embryopathy (author's transl)]. PMID- 4201012 TI - Microbody (peroxisome) matrix: transformation into tubular structures. PMID- 4201014 TI - Antibiotic usage and microbial resistance in an intensive care nursery. PMID- 4201013 TI - Total intravenous alimentation. PMID- 4201015 TI - Immunologic significance of aspergillin antigens of six species of Aspergillus in the serodiagnosis of aspergillosis. PMID- 4201016 TI - Nosocomial pneumonia. A continuing major problem. PMID- 4201017 TI - Response of Mycobacteria to ultraviolet light radiation. PMID- 4201018 TI - Immunoelectrophoretic analysis of antigenic constituents of Seibert fractions of mycobacterial culture filtrates. Identification with the proposed United States Japan reference nomenclature. PMID- 4201020 TI - The pathway of carbon dioxide assimilation in Rhodospirillum rubrum grown in turbidostat continuous-flow culture. PMID- 4201019 TI - The labeling of nucleic acids by radioactive precursors in the blue-green algae Anacystis nidulans and Synechocystis aquatilis Sanv. PMID- 4201021 TI - Optics and visual physiology. PMID- 4201022 TI - [Differentialdiagnostische Erwagungen bei Verletzungen des lateralen Bandapparaats am oberen Sprunggelenk]. PMID- 4201023 TI - [Conservative therapy of massive lateral ligament injuries of the ankle joint]. PMID- 4201024 TI - Experimental protein-energy malnutrition in baby baboons. 2. Liver pathology. PMID- 4201025 TI - Rate of passage of digesta in sheep. 3. Differential rates of passage of water and dry matter from the reticulo-rumen, abomasum and caecum and proximal colon. PMID- 4201026 TI - Comparison of the development of proteolytic activity in the abomasum of the preruminant calf with that in the stomach of the young rabbit and guinea-pig. PMID- 4201027 TI - Rate of passage of digesta in sheep. 4. Passage of marker through the alimentary tract and the biological relevance of rate-constants derived from the changes in concentration of marker in faeces. PMID- 4201028 TI - Circulating "big" insulin in protein-energy malnutrition. PMID- 4201029 TI - Comparison of final filtration devices. PMID- 4201030 TI - Drug additive compatibility--a manufacturer's concern. PMID- 4201031 TI - Detection of collagen degradation products in bone. PMID- 4201032 TI - Evaluation of several geometric models for estimation of left ventricular circumferential wall stress. PMID- 4201033 TI - Cardiovascular and metabolic effects of whole or fractionated gram-negative bacterial endotoxin in the unanesthetized Rhesus monkey. PMID- 4201034 TI - Enzyme-linked immunoassay for alpha-fetoprotein by competitive and sandwich procedures. PMID- 4201035 TI - Suggestions for economic survival. PMID- 4201036 TI - Serum immunoglobulin levels in farmer's lung disease. PMID- 4201037 TI - Platelet factor 4--antiheparin protein releasable from platelets. Purification and properties. PMID- 4201038 TI - The effect of amino acid solutions of differing composition on the nitrogen balance of postoperative patients. PMID- 4201039 TI - Acute forms of tuberculosis. PMID- 4201040 TI - Evaluation of acute chest pain. PMID- 4201041 TI - [Bacterial flora and current problems of resistence in urinary tract infections (author's transl)]. PMID- 4201042 TI - Pleiotropic nature of bacteriophage tolerant mutants obtained in early-blocked asporogenous mutants of Bacillus subtilis 168. PMID- 4201043 TI - Demonstration of Aleutian mink disease virus in cell culture. PMID- 4201044 TI - The effects of polychlorinated biphenyl on longevity of bobwhite quail (Collinus virginianus): a sex differential. PMID- 4201045 TI - Experimental emphysema in rats: elastolytic titer of inducing enzyme as determinant of the response. PMID- 4201046 TI - Solubilization and purification of human erythrocyte membrane acetylcholinesterase. PMID- 4201047 TI - In vivo stimulation of prolactin release in the rat by synthetic TRH. PMID- 4201048 TI - Structure and biologic functions of human IgD. II. Alteration of serum IgD levels during pregnancy. PMID- 4201049 TI - Present status of one-stage pharyngo-esophageal diverticulectomy. PMID- 4201050 TI - Teratogenic effects of carcinogen implantation in a regenerative field in Bufo arenarum tadpoles. PMID- 4201051 TI - [Therapy of late toxicoses with critical evaluation of commonly used drugs]. PMID- 4201052 TI - Nourishing the solute-sensitive patient. PMID- 4201053 TI - Immunological responses in the mole rat (Spalax leucodon). II. Serum proteins of nonimmunized mole rats. PMID- 4201054 TI - [A study of the production of anti-tyrosinase antibodies in rabbits. II. Circulating antibodies (author's transl)]. PMID- 4201055 TI - [The immunological activity of a composite antigen obtained by hybridization of endotoxins extracted from rough and smooth strains of "Salmonella" (author's transl)]. PMID- 4201056 TI - Humoral autoimmune response against rabbit male accessory glands elicited by untreated and chemically modified rabbit seminal plasma. PMID- 4201057 TI - Distribution of tubercle bacilli with various degrees of drug-resistance in the organs of guinea pigs. PMID- 4201058 TI - [Influence of exogenously administered orotic acid on enchondral ossification (author's transl)]. PMID- 4201059 TI - Absence of correlation between haemolysing splenic cell numbers and resistance to cancer induction by methylcholanthrene. PMID- 4201060 TI - Physicochemical studies of microbial cell walls. I. Comparative electrophoretic behavior of intact cells and isolated cell walls. PMID- 4201061 TI - Identification of presumptive histone messenger RNA in rapidly labelled polysomal RNA of mouse myelomas. PMID- 4201062 TI - Regulation of pancreatic alpha-amylase in the neonatal mouse. PMID- 4201063 TI - Perinatal brain damage: porencephaly in a cynomolgous monkey. PMID- 4201064 TI - Characterization of newborn leukocyte alkaline phosphatase. PMID- 4201065 TI - Intrauterine pneumonia. An experimental study. PMID- 4201066 TI - Protein and nucleic acid metabolism in insect fat body. PMID- 4201067 TI - The occurrence of anterior open bites in captive- and wild-born monkeys (Macaca fascicularis). PMID- 4201068 TI - Electrophoretic and antigenic properties of turtle myoglobins. PMID- 4201069 TI - Genetic programming for development in Drosophila. PMID- 4201070 TI - Allergens from short ragweed leaf tissue cultures. PMID- 4201071 TI - Bacterial virus contamination of fetal bovine sera. PMID- 4201072 TI - Isolation and growth characteristics of cell lines from bovine venous endothelium. PMID- 4201073 TI - The politics of developing a national health policy. PMID- 4201074 TI - Resource allocation, equality of access, and health. PMID- 4201075 TI - Health care in the United States: who pays? PMID- 4201076 TI - The origins of health insurance for the aged. PMID- 4201077 TI - More money into the medical sector: is this the answer? PMID- 4201078 TI - Ontogeny and localization of the crystallins during embryonic lens development in Xenopus laevis. PMID- 4201079 TI - A serologic comparison of bat complements. PMID- 4201080 TI - Quantitative variation in erythrocyte enzymes of the pig-tailed macaque, Macaca nemestrina. PMID- 4201081 TI - Nosematosis in a squirrel monkey (Saimiri sciureus). PMID- 4201082 TI - Ectopic splenic nodules in the pancreas of a capuchin monkey (Cebus albifrons). PMID- 4201083 TI - A new taxonomic tool: serological reactions in cross-immunized baboons. PMID- 4201084 TI - Genetic markers and baboon biology. PMID- 4201085 TI - [Stenosis of bronchi following prolonged nasotracheal intubation and trachoetomy in two premature infants (author's transl)]. PMID- 4201086 TI - A preliminary survey of the nematode parasites of some imported Old-World monkeys. PMID- 4201087 TI - Changes in aortic medial elastic structure at different sites in the primates Erythrocebus patas, Macaca irus and Callithrix jacchus. PMID- 4201088 TI - A restraining device for use when recording electrocardiograms in monkeys. PMID- 4201090 TI - [Nutrition and mental development (author's transl)]. PMID- 4201089 TI - [Parenteral feeding of premature infants (author's transl)]. PMID- 4201091 TI - Confirmatory studies in the prenatal diagnosis of sphingolipidoses. PMID- 4201092 TI - [Intestinal form of pyocyanosis in a child aged 2 years and 4 months]. PMID- 4201093 TI - Heterologous immunity in human malaria. PMID- 4201094 TI - [Diverticula of the greater curvature of the duodenum]. PMID- 4201095 TI - [Immunofluorescence (IFI) studies of some pararickettsia in cell cultures]. PMID- 4201096 TI - The microscope in the history of pathology. With a note on the pathology of fat cells. PMID- 4201097 TI - [Pathologic anatomic observations after three orthotopic allogenic transplantations of the liver in adults (author's transl)]. PMID- 4201098 TI - Antor-pyloric gastrinoma associated with pancreatic nesidioblastosis and proliferation of islets. PMID- 4201099 TI - Studies on dentinogenesis in the rat. Ethane-1-hydroxy-1,1-diphosphonate (EHDP) inhibits crystal growth in predentin calcification. PMID- 4201100 TI - Pancreatic and hepatic ultrastructure in offspring of rabbits with protein malnutrition. PMID- 4201101 TI - The use of viruses for the control of insect pests and disease vectors. Report of a joint FAO-WHO meeting on insect viruses. PMID- 4201102 TI - Estimation of immunoreactive insulin in serum, heparinized and EDTA-plasma. PMID- 4201103 TI - Protective effect of anti-mouse-skin-epithelium rabbit-IgG on survival of mouse skin homografts. PMID- 4201104 TI - Trabeculectomy in the owl monkey. PMID- 4201105 TI - Animal studies on the kinetics of benzidine and 3,3'-dichlorobenzidine. PMID- 4201106 TI - Enzymes of the glucuronic acid pathway in wistar and gunn rats and their heterozygotes. PMID- 4201107 TI - Suppression of transcription of the ribosomal RNA cistrons of Drosophila melanogaster in a structurally rearranged chromosome. PMID- 4201108 TI - Alkaline phosphatase of Drosophila melanogaster. II. Biochemical comparison among four allelic forms. PMID- 4201110 TI - A proteinase and proteinase inhibitor of mammalian sperm acrosomes. PMID- 4201109 TI - Characterization of acid phosphatase-1 null activity mutants of Drosophila melanogaster. PMID- 4201111 TI - Hormonal regulation of rat uterine glycogen metabolism. PMID- 4201112 TI - Soluble intracrystalline polysaccharides from coccoliths of Coccolithus huxleyi (Lohmann) Kamptner (I). PMID- 4201113 TI - Analysis of proliferation and differentiation of foetal granulocyte-macrophage progenitor cells in haemopoietic tissue. PMID- 4201114 TI - Circulating conversion products of C3 in liver disease. Evidence for in vivo activation of the complement system. PMID- 4201115 TI - Demonstration of the production of the long acting thyroid stimulator (LATS) by peripheral lymphocytes cultured in vitro. PMID- 4201116 TI - Survival of certain microorganisms subjected to rapid and very rapid freezing on membrane filters. PMID- 4201117 TI - Immunological studies in the multiple hemoglobins of tadpole and frog of Rana catesbeiana. PMID- 4201118 TI - The occurrence of ribothymidine, 1-methyladenosine, methylated guanosines and the corresponding methyltransferases in E. coli and Bacillus subtilis. PMID- 4201119 TI - Antibodies to rat brain choline acetyltransferase: species and organ specificity. PMID- 4201120 TI - The molecular status of the large polypeptides of erythrocyte membranes. PMID- 4201121 TI - Day care meets geriatric needs. PMID- 4201122 TI - Parvoviruses. PMID- 4201123 TI - An R.N. PMID- 4201124 TI - Subacute sclerosing panencephalitis measles virus: study of biological markers. AB - Comparative studies between two measles virus strains isolated from patients with subacute sclerosing panencephalitis (SSPE) and a prototype low tissue culture passage Edmonston measles virus are described. Differences were noted in several properties. The findings described in this report suggest that strains of measles virus associated with SSPE have different biological properties and apparently cannot be distinguished from laboratory and field strains of the virus. PMID- 4201126 TI - [Assistance of the aged patient unwilling to be discharged]. PMID- 4201125 TI - [Understnading of patients' needs in bedside nursing]. PMID- 4201127 TI - [Nursing of severely handicapped children with cerebral palsy and delayed sensory and psychological development]. PMID- 4201128 TI - [Assistance of a patient with diminished will to live in prolonged illness-a case of esophageal cancer with tube feeding through ileostomy]. PMID- 4201129 TI - [Assistance of an autistic patient with language disorder]. PMID- 4201131 TI - [On patients' rest]. PMID- 4201130 TI - [Assistance of psychiatric patients with problems with interpersonal relationship]. PMID- 4201132 TI - [Communications: a patient's eye view]. PMID- 4201133 TI - [Innovation of an attachment for the urinary tract for easier urination for patients following penile amputation]. PMID- 4201134 TI - [Social welfare budget in Japan. 6. Social insurance]. PMID- 4201135 TI - [Respiratory tract diseases in the aged]. PMID- 4201136 TI - [Nausea and vomiting]. PMID- 4201137 TI - [Introduction to the study of human development. 2. Physiology of the infant]. PMID- 4201138 TI - [Transfer technics. 2. Unassisted or partially assisted movement of patients]. PMID- 4201140 TI - [Assistance as a keypoint in nursing. 9. Re-evaluation of methods of assistance in clinical nursing]. PMID- 4201139 TI - [Visiting the place associated with the life of Florence Nightingale. 3. London]. PMID- 4201141 TI - [Psychology in nursing. 9. The bad object in object relation theory and structure of therapeutic environment]. PMID- 4201142 TI - [Death and nursing. 9. Clinical nursing and death. (2). Psychosomatic nursing]. PMID- 4201143 TI - [Medicine and civilization. 9. Creative child-rearing]. PMID- 4201144 TI - [The concept of medical education]. PMID- 4201145 TI - Estimation of total body potassium in normal adolescents by whole-body counting: age and sex differences. PMID- 4201146 TI - Role of external support in the prevention of ankle sprains. PMID- 4201147 TI - Advances in surgery. PMID- 4201148 TI - Advances in the treatment of infectious diseases. PMID- 4201150 TI - Preparation of an IgM and IgA enriched fraction for clinical use. PMID- 4201149 TI - Simultaneous extraction of RNA and DNA from rat liver with cupric sulfate. PMID- 4201151 TI - Adrenocortical cells in rats bearing a corticosterone secreting tumor. PMID- 4201152 TI - Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. Changes in the pars recta during fluorocitrate poisoning. PMID- 4201153 TI - Effect of hypoxia on the fine structure of the catecholamine-storing cells of the human fetal paraganglia. PMID- 4201155 TI - [Controlled parenteral feeding in premature infants]. PMID- 4201154 TI - The use of xylitol in long-term parenteral nutrition in dogs. PMID- 4201156 TI - [Diagnosis and therapy of threatened abortion--our experience]. PMID- 4201157 TI - Effect of polyphloretin-phosphate, an inhibitor of prostaglandins, on the spontaneous and induced motility of isolated rat uterus. PMID- 4201158 TI - Frostbite. A discussion of the problem and a review of an Alaskan experience. PMID- 4201159 TI - The independent functions of the two heads of the lateral pterygoid muscle. PMID- 4201160 TI - Ciliary activity in the human and Macaca nemestrina oviduct. PMID- 4201161 TI - [Colchicine inhibition of milk protein secretion]. PMID- 4201162 TI - [Increase of electric conductance by photo-excitation of artificial lipid membranes in the presence of dyes]. PMID- 4201163 TI - [Practical applications of echotomographic sections of the heart; prospects of the method for cardiac exploration]. PMID- 4201164 TI - [Use of partial pressure carbon dioxide electrodes for the specific measurement of urea in solution]. PMID- 4201165 TI - [Demonstration of autonomous mitochondrial mannosyl-transferase activity]. PMID- 4201166 TI - [Metabolic transformations of 3,5,5-trimethyl-cyclohexanone (dihydro-isophorone). Demonstration of a new metabolic pathway: dismutation]. PMID- 4201167 TI - [Demonstration of a nycthemeral rhythm of cell division in sarcomas induced by methylcholanthrene]. PMID- 4201168 TI - A human IgG myeloma protein crystallizing with rhombohedral symmetry. PMID- 4201169 TI - Alpha-foetoprotein: purification on sepharose-linked concanavalin-A. PMID- 4201170 TI - [The effect of hypocalcemia on basal gastric secretion (author's transl)]. PMID- 4201171 TI - [The means used in long-term parenteral nutrition (author's transl)]. PMID- 4201172 TI - Serum beta2-microglobulin levels in normal children and sex-linked agammaglobulinemia patients. PMID- 4201173 TI - Transcription specificity of an RNA polymerase fraction from bacteriophage SP01 infected B. subtilis. PMID- 4201174 TI - The pancreatic beta-cell recognition of insulin secretagogues. Inhibitory effects of a membrane probe on the islet uptake and insulin-releasing action of glibenclamide. PMID- 4201175 TI - Radiosensitization of bacterial spores by potassium permanganate. PMID- 4201176 TI - Mechanism for lysozyme-catalyzed hydrolysis. PMID- 4201178 TI - Interaction of glutaraldehyde with spheroplasts of Escherichia coli. PMID- 4201177 TI - Laboratory diagnosis of bovine paratuberculosis. PMID- 4201179 TI - Gliding motility in some non-spreading flexibacteria. PMID- 4201180 TI - Measurement of heat resistance parameters for spores isolated from canned products. PMID- 4201181 TI - Concanavalin A increases the strength of baby hamster kidney cell attachment to substratum. AB - The strength of attachment of normal and transformed baby hamster kidney cells was markedly increased when attached cells were treated with concanavalin A (Con A). The cells became less sensitive to detachment by physical shear or by treatment with trypsin or EDTA; however, their morphology, as observed by phase contrast microscopy, did not change. The effects of Con A were prevented by the simultaneous addition of either D-glucose or alpha-methyl-D-glucoside with the Con A. Also addition of these reagents to the attached cells after Con A treatment partially reversed the effects caused by Con A. Pre-treatment of the culture flasks with Con A before cell attachment resulted in an increase in the strength of cell attachment to the culture flasks as compared to untreated controls. PMID- 4201182 TI - Aporphines. 8. Total synthesis and pharmacological evaluation of (plus or minus) apomorphine, (plus or minus)-apocodeine, (plus or minus)-N-n propylnorapomorphine, and (plus or minus)-N-n-propylnorapocodeine. PMID- 4201183 TI - Synthesis and antitumor and antibacterial activity of benzoquinones related to the mitomycins. PMID- 4201184 TI - Pyrrole antibacterial agents. 1. Compounds related to pyoluteorin. PMID- 4201185 TI - 14Alpha, 17 alpha-alkylidenedioxy steroids. 2. 19-Nor-9 alpha, 10 beta- and 19 nor-9 beta, 10 alpha-progesterone analogs. PMID- 4201186 TI - Terminal riboadenylate transferase: a poly A polymerase in purified vaccinia virus. AB - Purified vaccinia virus treated with Triton X-100 catalyzes the incorporation of ATP into an acid-insoluble product. The enzymatic activity responsible for the ATP polymerization is demonstrated to be different from vaccinia RNA polymerase in its preferential use of ATP as substrate and on the basis of heat stability, pH optima, and metal ion requirement. The ATP polymerization reaction is stimulated 10-fold by the addition of rA(pA)(5.) In accordance with our earlier terminology, we call this Mn(2+)-dependent enzyme terminal riboadenylate transferase to distinguish it from Mg(2+)-dependent poly A polymerase. PMID- 4201187 TI - Specificity of formation of complexes between coat protein and bacteriophage f2 RNA. AB - The specificity of formation of phage f2 RNA-protein complexes was studied. Complex I contains up to 8 mol of coat protein per 1 mol of RNA. Its formation proceeds equally well in medium (i) without magnesium ions, (ii) containing magnesium ions, (iii) containing 4 mM EDTA, and (iv) at temperatures from 0 to 45 C. Complex II contains up to 200 mol of coat protein per 1 mol of RNA. Its formation is inhibited by the presence of magnesium ions in medium. Formaldehyde- or methoxyamine-treated f2 RNA in which only exposed bases were modified showed a normal pattern of complex II formation, whereas formation of complex I was inhibited or abolished. We conclude that complex I formation involves the interaction between coat protein and specific region of exposed bases in RNA. A possible site of attachment of coat protein is discussed. PMID- 4201188 TI - Replication of dengue virus type 2 in Aedes albopictus cell culture. AB - The replication of type 2 dengue (D-2) virus in Aedes albopictus (Aal) mosquito cell cultures differed from that in vertebrate (LLC-MK2) rhesus monkey kidney cells. Virus readily replicated in Aal cells at either 30 or 37 C, but had no apparent effect on the host cell. Persistent infection was established with continual virus production for at least 6 months, although the virulence of progeny virus for both suckling mice and LLC-MK2 cells became attenuated. Density gradient analysis of infected Aal cell supernatant products indicated that only complete virus was released, in contrast to infected LLC-MK2 cells which also released incomplete virus. The surface antigens of the virus produced in Aal cells appeared to be considerably modified in that antiserum to vertebrate cell produced D-2 virus did not block hemagglutination, whereas anti-Aal cell antiserum did. Virus infectivity could be neutralized by the antiserum to D-2 virus grown in vertebrate cells, however. Virus produced in LLC-MK2 cells did not demonstrate a similar host-cell modification. These results may reflect a difference in the mechanism by which D-2 virus matures in Aal cells. PMID- 4201190 TI - [Stomach diverticulum, its diagnosis and therapy]. PMID- 4201189 TI - Effect of nalidixic acid on PBS2 bacteriophage infection of Bacillus subtilis. AB - Infection of Bacillus subtilis by PBS2 phage, whose DNA contains uracil instead of thymine, is relatively unaffected by low concentrations of nalidixic acid which severely inhibit B. subtilis DNA synthesis. High concentrations of nalidixic acid do inhibit PBS2 DNA synthesis, but more severely reduce the burst size of PBS2 infections. Hydroxyurea blocks PBS2 DNA synthesis, preventing progeny phage production. PMID- 4201191 TI - Hand, foot and mouth disease: an outbreak with interesting virological features. PMID- 4201192 TI - An evaluation of the use of sensitized latex particles for the detection of the hepatitis-associated antigen. PMID- 4201193 TI - [New aspects of viral hepatitis]. PMID- 4201194 TI - [Case of systemic mastocytosis]. PMID- 4201195 TI - Acute inhalation toxicology and proposed emergency exposure limits of nitrogen trifluoride. PMID- 4201196 TI - Induced reversible pigment alteration in Stentor coeruleus. PMID- 4201197 TI - The role of acrocentric chromosomes in nucleolar organization. II. Constancy of the nucleolar area independent of the number of acrocentric chromosomes in meningioma cell cultures. PMID- 4201198 TI - Fine structure and silver-staining patterns of lysosome-like bodies in absorptive cells of the small intestine in normal children and children with a lysosomal storage disease. PMID- 4201199 TI - Further studies on the ultrastructure of the pars distalis of castrated male mice pituitary. PMID- 4201200 TI - [Fine structure of an endocrine active carcinoma of the parathyroid gland (author's transl)]. PMID- 4201201 TI - Platelets and carbon clearance rates in rabbits affected by a tubercle bacillary lipid or endotoxin. PMID- 4201202 TI - Deletion of cells by apoptosis during castration-induced involution of the rat prostate. PMID- 4201203 TI - Teratocarcinoma with the capacity for differentiation restricted to neuro ectodermal tissue. PMID- 4201204 TI - Degeneration and regeneration of the adrenergic nerves in the rat iris induced by dihydroxytryptamines. PMID- 4201205 TI - [Atypical nuclear invaginations in a case of lymphoblastic lymphosarcoma (author's transl)]. PMID- 4201206 TI - Proliferation of epithelial cells in the jejunal crypts of adrenalectomized and adrenocortical hormone treated rats. PMID- 4201207 TI - Effect of an a' aqueous extract of small intestinal mucosa on the G-2 phase of jejunal proliferative cells in mice. PMID- 4201208 TI - [Age-dependent autoradiographic study on adrenal cortex proliferation in male rats following continuous 3H-thymidine infusion]. PMID- 4201209 TI - Visualization of human glomerular changes by scanning electron microscopy. PMID- 4201210 TI - Effects of azide, thioglycollic acid, and nitrosoguanidine on growth and nitrogen fixation in different clones of the blue-green alga Cylindrospermum majus. PMID- 4201211 TI - Descent of cerevrospinal fluid to spinal subarachnoid space. PMID- 4201212 TI - Lactose feeding and lactase deficiency. PMID- 4201213 TI - Microbial contamination of the gut: another feature of malnutrition. PMID- 4201214 TI - Plasma amino acid curve in rats force-fed a single meal lacking an essential amino acod. PMID- 4201215 TI - Serum vitamin A in protein-calorie malnutrition. PMID- 4201216 TI - Lactose feeding in lactose-intolerant monkeys. PMID- 4201217 TI - Lens depression and aqueous outflow in enucleated primate eyes. PMID- 4201218 TI - Ascending and descending optic atrophy produced experimentally in squirrel monkeys. PMID- 4201219 TI - Cloverleaf skull syndrome. PMID- 4201220 TI - Norrie's disease (hereditary oculo-acoustic-cerebral degeneration). Report of a United States family. PMID- 4201221 TI - Epiphrenic diverticula. An analysis of 80 cases. PMID- 4201222 TI - Immune response of the bovine fetus to several antigens. PMID- 4201223 TI - Thiosulfate and survival of Leptospira autumnalis Akiyami A. PMID- 4201224 TI - Thyroid abnormalities in renal failure. A study of 53 patients on chronic hemodialysis. PMID- 4201225 TI - Pseudomonas aeruginosa vaccine in cancer patients. PMID- 4201226 TI - Immunocompetence of patients with protein-calorie malnutrition. The effects of nutritional repletion. PMID- 4201227 TI - Pathogenesis of "transplant lung". I. Interstitial pulmonary edema. PMID- 4201229 TI - Red-cell fluid and electrolytes during hemorrhagic shock in the monkey. PMID- 4201228 TI - Pseudomyxoma peritonaei: a report of ten cases. PMID- 4201230 TI - Chlorpromazine treatment of disturbed monkeys. PMID- 4201231 TI - The phenogenetics of a super-suppressor in Drosophila melanogaster. 3. Suppression at individual loci. PMID- 4201232 TI - The melanocyte system of cattle skin. II. Melanotic melanocytes of epidermis and dermis. PMID- 4201233 TI - A survey of the genitalia of bulls in Northern Australia. PMID- 4201234 TI - Differences in eukaryotic ribosomes detected by the selective action of an antibiotic. PMID- 4201235 TI - Effect of the administration of L-azetidine-2-carboxylic acid on albumin and transferrin biosynthesis by liver slices of rats treated with carbon tetrachloride. PMID- 4201236 TI - Studies on the biological properties of coelomic fluid of sea urchin. I. Naturally occurring hemolysin in sea urchin. PMID- 4201237 TI - Differences in the content of chondroitin sulfate C and chondroitin sulfate A in the epiphysial growth cartilages of human vertebrae and long bones. PMID- 4201238 TI - Adenylate cyclase activity in isolated rat islets of Langerhans. Effects of agents which alter rates of insulin secretion. PMID- 4201240 TI - Letter: 23Na interaction with bacterial surfaces: a comment on nuclear magnetic resonance invisible signals. PMID- 4201239 TI - Coordination of heme and globin synthesis in primate reticulocytes. PMID- 4201241 TI - Serological tests for syphilis in pregnancy. False and missed positive reactions. PMID- 4201242 TI - Survival of Neisseria gonorrhoeae in an artificial subcutaneous cavity of the mouse. PMID- 4201243 TI - Growth and effect of Neisseria gonorrhoeae in organ cultures. PMID- 4201244 TI - Transgrow (Clinicult) in the laboratory diagnosis of gonorrhoea. PMID- 4201245 TI - Vancomycin-sensitive strains of Neisseria gonorrhoeae. A problem for the diagnostic laboratory. PMID- 4201246 TI - Incidence of gonorrhoea in Denmark, 1957-1971. PMID- 4201247 TI - Collagenolytic activities of squamous cell carcinoma of the skin. PMID- 4201249 TI - The effect of haemodialysis on the binding capacity of albumin. PMID- 4201248 TI - Microsomal metabolism of dimethylnitrosamine and the cytochrome P-450 dependency of its activation to a mutagen. PMID- 4201250 TI - The use of polymerized antisera for the determination of human placental alkaline phosphatase in pregnancy sera. PMID- 4201251 TI - [Purification and properties of erythrocyte alkaline phosphatase in familial erythrocytosis (author's transl)]. PMID- 4201252 TI - A sensitive radioimmunoassay for thyrotropin releasing hormone. PMID- 4201253 TI - Factors in blood influencing the determination of thyrotropin releasing hormone. PMID- 4201254 TI - Evaluation of a specific protein analyser. PMID- 4201256 TI - Plasma thyrotropin levels in severe infantile malnutrition. PMID- 4201255 TI - Work simplification of a competitive protein binding analysis for serum thyroxine. A study of some analytical variables affecting accuracy and precision. PMID- 4201257 TI - Prolactin production by monkey (Macaca mulatta) anterior pituitaries cultured in vitro. PMID- 4201258 TI - Loss of immunoreactivity of human serum parathyroid hormone by the action of rat kidney enzyme, preferentially hydrolyzing parathyroid hormone. PMID- 4201259 TI - Pony cecum vs. steer rumen: the effect of oats and hay on the microbial ecosystem. PMID- 4201260 TI - Effect of EDTA on utilization of dietary zinc by G-F swine. PMID- 4201261 TI - Mathematical model of a head subjected to an angular acceleration. PMID- 4201262 TI - Defective ristocetin-induced platelet aggregation in von Willebrand's disease and its correction by factor VIII. AB - The antibiotic ristocetin, in concentrations of 1.0-1.5 mg/ml, aggregated normal platelets in citrated platelet-rich plasma by a mechanism in which the release reaction played only a minor role. Platelet aggregation by ristocetin in a concentration of 1.2 mg/ml was absent or markedly decreased in 10 patients with von Willebrand's disease. Lesser degrees of abnormality were obtained with a concentration of 1.5 mg/ml. The magnitude of the defect in ristocetin-induced platelet aggregation correlated well with the degree of abnormality of the bleeding time and the levels of antihemophilic factor (AHF, VIII(AHF)) procoagulant activity. In all patients, the defect in ristocetin-induced platelet aggregation was corrected in vitro by normal plasma. Correction was also obtained with a fraction of normal cryoprecipitate that eluted in the void volume with VIII(AHF) after chromatography on a gel that excludes molecules larger than 5 x 10(6). A similar fraction, devoid of VIII(AHF) activity, obtained from patients with von Willebrand's disease had no corrective effect, but fractions obtained from patients with hemophilia were just as effective as those obtained from normal subjects. The correction activity of plasma and partially purified factor VIII was inhibited by a rabbit antibody to human factor VIII but not by a human antibody against VIII(AHF) procoagulant activity. The studies provide further evidence that patients with von Willebrand's disease are deficient in a plasma factor that is necessary for normal platelet function. The activity of this factor appears to be associated with factor VIII but is unrelated to VIII(AHF) procoagulant activity. PMID- 4201263 TI - Evidence that the ciliary inhibitor of cystic fibrosis is not an antibody. AB - An inhibitor of ciliary activity is present in the serum of cystic fibrosis (CF) patients and heterozygotes. Fractionation of CF serum has indicated that the inhibitor is associated with the serum IgG fraction. This study compared the activity of the CF inhibitor to that of rabbit antibody preparations directed against oyster cilia. The aim of this investigation was to determine whether the ciliary inhibitory mechanism in cystic fibrosis is related to a typical immunological reaction. Results from experiments utilizing fluorescent antibody techniques demonstrated that an antiserum directed against oyster ciliated epithelium binds immunologically with both human bronchial and oyster epithelial tissue. Results from experiments utilizing immunofluorescent tracing, passive hemagglutination, double immunodiffusion, and papain digestion, however, indicated that the interaction between the oyster cilia and the CF serum inhibitor was not a typical antigen-antibody reaction. PMID- 4201264 TI - Antihemophilic factor antigen. Localization in endothelial cells by immunofluorescent microscopy. AB - The tissue localization of antihemophilic factor (AHF, Factor VIII) has been determined by immunofluorescent studies using monospecific rabbit antibody to human AHF. Specific staining demonstrating AHF antigens has been identified in endothelial cells of a wide range of human tissues. The staining pattern was observed in endothelial cells of arteries, capillaries, and veins as well as the cells lining hepatic and splenic sinusoids. Specific fluorescence was limited to these endothelial cells in sections of kidney, liver, spleen, lymph node, cardiac and smooth muscle, thyroid, umbilical cord, and skin. Absorption studies established that the staining was specific for cells in which there were proteins that had AHF antigens. The demonstration of fluorescence within the cytoplasm of endothelial cells suggests that these cells synthesize proteins that have AHF antigens. PMID- 4201265 TI - Suppression of pituitary TSH secretion in the patient with a hyperfunctioning thyroid nodule. AB - 10 patients with a single hyperfunctioning thyroid nodule each were studied for pituitary thyrotropin (TSH) suppression. They were judged to be euthyroid on clinical grounds. The total thyroxine (T(4)D), free thyroxine (FT(4)), total triiodothyronine (T(3)D), and free triiodothyronine (FT(3)) were normal in most of the patients. Incorporation of (131)I into the hyperfunctioning thyroid nodules was not suppressed by the administration of physiological doses of T(3). Basal serum TSH concentrations were undetectable (<0.5 - 1.0 muU/ml) in all patients. The metabolic clearance of TSH in one patient before and after excision of the thyroid nodule was unchanged (40 vs. 42 ml/min) whereas the calculated production rate was undetectable before the operation (<29 mU/day) and normal after (103 mU/day). These data, in one patient, suggest that the undetectable concentration of TSH in these patients is a result of suppressed TSH secretion rather than accelerated TSH clearance. In eight patients, basal serum TSH concentrations failed to increase after the intravenous administration of 200 mug of thyrotropin-releasing hormone (TRH); minimal increases in serum TSH concentrations were observed in two patients. The suppression of TSH was evident despite "normal" concentrations of circulating thyroid hormones. The observation that normal serum concentrations of T(4)D, FT(4), T(3)D, and FT(3) may be associated with undetectable basal serum TSH concentrations and suppressed TSH response to TRH was also found in four hypothyroid patients given increasing doses of L-thyroxine and sequential TRH stimulation tests. PMID- 4201266 TI - Interrelationships between the human alveolar macrophage and alpha-1-antitrypsin. AB - Alveolar macrophages lavaged from human lungs contain protease activity at an optimum pH of 3.0 and possibly a lesser peak of activity at pH 5.5. Protease activity measured at pH 4.1 is inhibited by purified alpha-1-antitrypsin. Fluorescent antibody studies of human alveolar macrophages showed that alpha-1 antitrypsin is present in normal alveolar macrophages. In addition, macrophages from a patient with a homozygous deficiency of alpha-1-antitrypsin exhibited less fluorescence when incubated in autologous serum than the same macrophages incubated in normal serum. Macrophages from normal subjects showed maximal fluorescence when removed from the lung and additional incubation with serum did not increase fluorescence. These results implicate the human alveolar macrophage as a possible source of an enzyme that may cause emphysema in patients deficient in alpha-1-antitrypsin. They also show that alpha-1-antitrypsin has access to the alveolus in normal subjects. PMID- 4201267 TI - The effects of nitroglycerin on coronary collaterals and myocardial contractility. AB - Nitroglycerin (TNG) causes a prolonged dilatation of coronary collaterals. To demonstrate a functional significance of this dilatation we measured the effect of TNG on myocardial contractile force in dogs 2(1/2)-4 wk after the left anterior descending coronary artery (LAD) had been embolized in closed-chest animals. Development of collaterals was documented by angiography. Via a left thoracotomy the main left coronary artery (LCA) and LAD distal to the embolized plug were cannulated. Coronary flow and perfusion pressure were recorded. Contractile force was measured with gauges sutured to epicardial areas supplied by the left circumflex coronary artery (LCf) and occluded LAD. Coronary perfusion pressure in the LCA was gradually decreased until the contractile force recorded by the LAD gauge diminished while the LCf gauge was unaffected. Under these conditions, with coronary perfusion pressure held constant with the aid of a Starling resistance, TNG (18 mug) injected into the LCA increased peripheral LAD pressure by 3-12 mm Hg and contractile force in the LAD region by 36% (range 20 90%), returning it to near-normal levels, while having minimal effect in the LCf area. These changes persisted for 5 min. When LCf and LAD areas were both ischemic, intracoronary TNG had minimal effect on peripheral LAD pressure and contractile force. Thus, TNG causes prolonged dilatation of coronary collaterals and presumed increased collateral flow with subsequent enhancement of myocardial contractile force in ischemic areas. This effect is seen only when ischemia is limited to an area supplied by the collaterals. When the whole heart is ischemic, collaterals are unresponsive to TNG, suggesting that these collaterals dilate fully when the regions from which they originate become ischemic. PMID- 4201270 TI - Radioimmunoassay of thyrotrophin releasing hormone. PMID- 4201269 TI - Inhibition of vasopressin-stimulated urea transport across the toad bladder by thiourea. AB - The mammalian antidiuretic hormone, 8-arginine-vasopressin, was found to increase net mucosal-to-serosal urea flux across the isolated toad urinary bladder 13 fold. This urea flux was accompanied by a 24-fold increase in solute-linked water movement across the membrane. Net urea flux and urea-linked volume flux were inhibited by 50% or more when thiourea was added to the mucosal medium at concentrations equal to those of urea. In contrast, thiourea did not inhibit osmotic water flux across the bladder in the presence of vasopressin. These observations are consistant with the view that thiourea and urea compete for a common site on a membrane carrier molecule. When bladders were exposed to vasopressin on the serosa and subsequently fixed with 1% glutaraldehyde on the mucosa, they were found to retain 74% of their prefixation permeability to urea. Net urea flux across these fixed bladders (in the absence of vasopressin) was markedly inhibited by thiourea, whereas osmotic water flux was not inhibited. These studies suggest that vasopressin induces the formation of "urea-channels" in the membrane that can be preserved by glutaraldehyde and blocked by thiourea. PMID- 4201268 TI - Quantitative determination of antibody to gonococcal pili. Changes in antibody levels with gonococcal infection. AB - Gonococcal pili, pure by the criteria of electron microscopic examination and polyacrylamide gel electrophoresis in sodium dodecyl sulfate, have been prepared by repeated cycles of precipitation with 0.1 M MgCl(2), followed by dissolution in 0.01 M Tris pH 8, 0.01 M NaN(3). Using a fluorescein-conjugated antibody prepared to pili from a single strain, pilar antigen(s) was found to be present in each of 18 strains of gonococci tested, and absent from strains of pilated meningococci, nonpathogenic Neisseria sp., and Escherichia coli. Purified pili, labeled with (125)I were used in an antigen binding assay to quantitatively measure antibody to pili in rabbit sera and in 561 human sera. The range of antibody activity for 133 persons unlikely to have experienced gonorrhea was 0.1 1.6 mug/ml with a geometric mean of 0.5 mug/ml. This geometric mean antibody activity was significantly lower than the geometric mean for asymptomatically infected males (1.0 mug/ml, P < 0.002), males with symptomatic gonococcal anterior urethritis (1.6 mug/ml, P < 0.001), or asymptomatically infected females (4.2 mug/ml, P < 0.001). Antibody appeared in elevated levels (> 1.6 mug/ml) 2-3 wk after infection and returned toward control levels 1 or more months after treatment. Antibody levels higher than 1.6 mug/ml were found in 26 (50%) of 52 males with gonococcal anterior urethritis, in 10 (33%) of 30 males with asymptomatic urethral infection and in 50 (89%) of 56 asymptomatically infected females. In a high-risk group of 103 females for whom culture results and antibody to pili were compared, 58 (57%) had elevated antibody levels to pili and 86% of the infected females were within this seropositive group. The antigen binding assay may provide a means to detect asymptomatic gonococcal infection in women. PMID- 4201271 TI - Subcellular distribution and some properties of the enzyme activity involved in the breakdown of tritiated lysine vasopressin by bovine neurohypophyses. PMID- 4201272 TI - The designation of the major guinea-pig neural lobe protein as a neurophysin. PMID- 4201273 TI - Glyceryl trinitrate and pentrinitrol (pentaerythritol trinitrate): comparative cardiovascular effects in dog, cat and rat by different routes of administration. PMID- 4201274 TI - Effect of the prostaglandin synthesis inhibitors indomethacin and eicosa 5,8,11,14-tetraynoic acid on adrenergic responses in dog cutaneous vasculature. PMID- 4201275 TI - Sulfhydryl requirement for relaxation of vascular smooth muscle. PMID- 4201276 TI - Metabolism of 3H-estrone sulfate perfused in vivo through a rhesus monkey liver. PMID- 4201277 TI - [Microbial hydrogenation of the aromatic moiety of 17 alpha ethinyl estradiol]. PMID- 4201278 TI - The effect of glyceryl trinitrate (nitroglycerin on the coronary hemodynamics in man. PMID- 4201279 TI - [Role of the corpus callosum in the visual adjustment of motricity]. PMID- 4201280 TI - [Letter: Lasting and active endocrine pancreas homografts]. PMID- 4201281 TI - [Tube feeding. An experience in a central department of dietetics in a 3000 bed university hospital]. PMID- 4201282 TI - [Therapeutic correction of hereditary idiopathic hyperlipemia. Evaluation of a standard diet]. PMID- 4201283 TI - [Letter: How to transport Neisseria meningitidis strains]. PMID- 4201284 TI - [Letter: Severe hypoglycemia in Waldenstrom's disease]. PMID- 4201285 TI - Morphological and autoradiographical investigations on experimental carcinogenesis and polyp development in the intestinal tract of rats and mice. PMID- 4201286 TI - [Changes in the sympathetic nerves in the parotid gland following guanacline medication. Ultrastructural observations (author's transl)]. PMID- 4201287 TI - [Ultrastructural study of two cases of granulomatous orchitis (author's transl)]. PMID- 4201288 TI - [Investigations on the ultrastructure of the small intestine of FW 49-rats reared in germfree conditions. 1. Epithelial findings with special reference to Paneth cells (author's transl)]. PMID- 4201289 TI - [Ultrastructural study of the adrenal tumours in Cushing's syndrome (author's transl)]. PMID- 4201290 TI - [Intercapillary glomerulosclerosis in hepatic cirrhosis (author's transl)]. PMID- 4201291 TI - Radioimmunological evidence for early functional activity in chick embryonic beta cells. PMID- 4201292 TI - Timely topics in microbiology 1971: gram negative bacteria. PMID- 4201293 TI - A microneutralization test for canine distemper virus. PMID- 4201294 TI - Vaccination of calves and milking cows with different strains of Theileria annulata. PMID- 4201295 TI - Propranolol and LB 46 (prinodolol) in angina pectoris. A comparative long-term ergometric study. PMID- 4201296 TI - Linkage data on Rh, PGM1, PGD, Peptidase C and Fy from family studies. PMID- 4201297 TI - The blood groups of Icelanders. PMID- 4201299 TI - Evaluation of an indirect fluorescent antibody test for detecting Babesia argentina infection in cattle. PMID- 4201298 TI - [Undesirable effect of antiepileptic therapy in a patient with epilepsy and maturational focal discharges]. PMID- 4201300 TI - A cowpox-like infection in man caused by Coxsackie A type 16 virus. PMID- 4201301 TI - A rapid method for the purification of glycogen synthetase I and D utilising concanavalin A bound to agarose. PMID- 4201302 TI - Galactosyl (alpha 1--4)galactosylceramide: galactosyl hydrolase activity in normal and Fabry plasma. PMID- 4201303 TI - Pronase digestion of amino-acid binding components on the surface of Bacillus subtilis cells and minicells. PMID- 4201305 TI - A comparison of the unfolding and dissociation of the large ribosome subunits from Rhodopseudomonas spheroides N.C.I.B. 8253 and Escherichia coli M.R.E. 600. AB - 1. The behaviour of the large ribosomal subunit from Rhodopseudomonas spheroides (45S) has been compared with the 50S ribosome from Escherichia coli M.R.E. 600 (and E. coli M.R.E. 162) during unfolding by removal of Mg(2+) and detachment of ribosomal proteins by high univalent cation concentrations. The extent to which these processes are reversible with these ribosomes has also been examined. 2. The R. spheroides 45S ribosome unfolds relatively slowly but then gives rise directly to two ribonucleoprotein particles (16.6S and 13.7S); the former contains the intact primary structure of the 16.25S rRNA species and the latter the 15.00S rRNA species of the original ribosome. No detectable protein loss occurs during unfolding. The E. coli ribosome unfolds via a series of discrete intermediates to a single, unfolded ribonucleoprotein unit (19.1S) containing the 23S rRNA and all the protein of the original ribosome. 3. The two unfolded R. spheroides ribonucleoproteins did not recombine when the original conditions were restored but each simply assumed a more compact configuration. Similar treatments reversed the unfolding of the E. coli 50S ribosomes; replacement of Mg(2+) caused the refolding of the initial products of unfolding and in the presence of Ni(2+) the completely unfolded species (19.1S) again sedimented at the same rate as the original ribosomes (44S). 4. Ribosomal proteins (25%) were dissociated from R. spheroides 45S ribosomes by dialysis against a solution with a Na(+)/Mg(2+) ratio of 250:1. During this process two core particles were formed (21.2S and 14.2S) and the primary structures of the two original rRNA species were conserved. This dissociation was not reversed. With E. coli 50S approximately 15% of the original ribosomal protein was dissociated, a single 37.6S core particle was formed, the 23S rRNA remained intact and the ribosomal proteins would reassociate with the core particle to give a 50S ribosome. 5. The ribonuclease activities in R. spheroides 45S and E. coli M.R.E. 600 and E. coli M.R.E. 162 50S ribosomes are compared. 6. The observations concerning unfolding and dissociation are consistent with previous reports showing the unusual rRNA complement of the mature R. spheroides 45S ribosome and show the dependence of these events upon the rRNA and the importance of protein-protein interactions in the structure of the R. spheroides ribosome. PMID- 4201306 TI - Cholesterol ester hydrolysis in aortic tissue. PMID- 4201304 TI - The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism. AB - 1. alpha(2)-Macroglobulin is known to bind and inhibit a number of serine proteinases. We show that it binds thiol and carboxyl proteinases, and there is now reason to believe that alpha(2)-macroglobulin can bind essentially all proteinases. 2. Radiochemically labelled trypsin, chymotrypsin, cathepsin B1 and papain are bound by alpha(2)-macroglobulin in an approximately equimolar ratio. Equimolar binding was confirmed for trypsin by activesite titration. 3. Pretreatment of alpha(2)-macroglobulin with a saturating amount of one proteinase prevented the subsequent binding of another. We conclude that each molecule of alpha(2)-macroglobulin is able to react with one molecule of proteinase only. 4. alpha(2)-Macroglobulin did not react with exopeptidases, non-proteolytic hydrolases or inactive forms of endopeptidases. 5. The literature on binding and inhibition of proteinases by alpha(2)-macroglobulin is reviewed, and from consideration of this and our own work several general characteristics of the interaction can be discerned. 6. A model is proposed for the molecular mechanism of the interaction of alpha(2)-macroglobulin with proteinases. It is suggested that the enzyme cleaves a peptide bond in a sensitive region of the macroglobulin, and that this results in a conformational change in the alpha(2) macroglobulin molecule that traps the enzyme irreversibly. Access of substrates to the active site of the enzyme becomes sterically hindered, causing inhibition that is most pronounced with large substrate molecules. 7. The possible physiological importance of the unique binding characteristics of alpha(2) macroglobulin is discussed. PMID- 4201307 TI - The effects of frontal cortical ablations on alcohol selection and emotionality in pigtail monkeys (Macaca nemistrina). PMID- 4201308 TI - Toxicology and pharmacology of the nitrosoureas. PMID- 4201309 TI - Formulation of three nitrosoureas for intravenous use. PMID- 4201311 TI - Swine abscesses caused by Lancefield's group E streptococci. XI. Application of the hemagglutination test to demonstrate a correlation between the antigens of group E and streptococcus uberis, and their relation to antibodies induced by unknown organisms. PMID- 4201310 TI - Response of vaccinated swine to group E streptococcus exposure. PMID- 4201313 TI - A double-blind, comparative clinical trial with ludiomil (CIBA 34,276-Ba) and amitriptyline in newly admitted depressed patients. PMID- 4201312 TI - Bromazepam and phenobarbital in anxiety: a controlled study. PMID- 4201314 TI - A controlled study of single-dose administration of imipramine pamoate in endogenous depression. PMID- 4201315 TI - Experiences on a sustained-release procainamide preparation. PMID- 4201318 TI - [Frequency of occurrence of a dominant mutation in human neurofibromatosis]. PMID- 4201316 TI - Diuretic effect of butoxymethylen furosemide (FFBU) in healthy subjects: a preliminary study. PMID- 4201319 TI - [Characteristics of the distribution of 5-methylcytosine in pyrimidine isoplites of different DNAs, methylated in the heterologous DNA-methylase reaction]. PMID- 4201317 TI - Clinical and laboratory evaluation of cefazolin: a new cephalosporin antibiotic in pediatric patients. PMID- 4201320 TI - Conservation of intestinal bile acid concentration after ileal resection. PMID- 4201321 TI - Serological reactions of glycolipids from streptococcal L-forms. AB - Parent bacteria and L-forms of some streptococci of group A, group D, and Streptococcus MG share common antigens as shown by cross-reactivity in growth inhibition, complement fixation, and Ouchterlony tests. Cross-reactivity between these streptococci or their L-forms with a staphylococcal L-form, or Mycoplasma pneumoniae, was found only rarely and only in low-titer complement fixation tests. Removal of all three serological reactivities from positive antisera by addition of chloroform-methanol (7:3) extracts of the streptococci or their L forms, and failure to remove activities by protein extracts, indicated the glycolipid nature of the cross-reacting antigenic determinants. PMID- 4201322 TI - Purification and characterization of thermostable direct hemolysin of Vibrio parahaemolyticus. AB - A thermostable direct hemolysin was purified from culture filtrates of Vibrio parahaemolyticus. The purified hemolysin gave one precipitation line with the antihemolysin antiserum on agar-gel diffusion test and a single band on polyacrylamide gel electrophoresis. The hemolysin was not inactivated by heating at 70 to 100 C for 10 min. The hemolytic activity was not enhanced by the addition of lecithin. It was demonstrated that the hemolysin was a protein with a molecular weight of approximately 118,000. Amino acid analysis revealed that 43% of total amino acids were acidic amino acids, whereas 11% were basic amino acids. PMID- 4201324 TI - Platelet enhancement of postphagocytic destruction of Listeria monocytogenes in cultured mouse peritoneal macrophages. AB - Rabbit platelets enhance the bactericidal capability of cultured mouse peritoneal macrophages against Listeria monocytogenes. PMID- 4201323 TI - Isolation of a new simian foamy virus from a spider monkey brain culture. AB - A syncytium-forming (foamy) virus was isolated from a spider monkey brain cell culture. Cytopathic effect was observed both in the brain culture and in human embryonic kidney cells. Neutralizing antibody was present in the sera of the spider monkey from whom the isolation was made. The virus was inhibited by 5 bromo-2-deoxyuridine (20 mug/ml), contained a ribonucleic acid-dependent deoxyribonucleic acid polymerase, and had an infectivity peak at 1.15 g/cm(3) in a sucrose density gradient. The virus passed through a 220-nm but not a 100-nm membrane filter, was chloroform sensitive, and was inactivated at 56 C in 30 min. Hemagglutinating and hemadsorption activity was not noted with a variety of erythrocytes. The virion was spherical, formed in the cytoplasm, and was 105 to 115 nm in diameter. Ring-shaped nucleoids, 45 to 50 nm in diameter, were associated with tubular profiles. The virus was not neutralized by sera prepared against known viruses, including simian foamy virus types 1 through 7, Mason Pfizer monkey virus, and bovine syncytial and measles viruses. Sera from a rabbit hyperimmunized with the isolate and sera from 19 spider monkeys had neutralizing antibody to the isolate; however, these sera did not cross-react with simian foamy virus types 1 through 7. Neutralizing antibody to the isolate was not detected in sera from 16 humans, 9 rhesus monkeys, and 10 chimpanzees. PMID- 4201326 TI - Determination of mean cell size of Tetrahymena in growing cultures. PMID- 4201325 TI - Production of exo-beta-N-acetylglucosaminidase by Bacillus subtilis B. PMID- 4201327 TI - The neutral and alkaline proteases of Aspergillus nidulans. PMID- 4201328 TI - Effect of autologous bone marrow transplantation and an anabolic steroid on erythropoietin production and hemopoietic recovery after whole body irradiation and treatment with alkylating agents. PMID- 4201329 TI - [Observation of a nursing scene]. PMID- 4201331 TI - [Nursing of patient with deglutition and urination difficulties due to cerebrovascular disorder]. PMID- 4201330 TI - [Nursing of a dying patient at the terminal stage of cancer of the cervical spine]. PMID- 4201332 TI - [Pre and postnatal care of a patient with a heart disease]. PMID- 4201333 TI - [Nursing of a patient with cerebral apoplexy--from the onset of the disease to rehabilitation stage]. PMID- 4201335 TI - [Clinical conference. 10. Improvement of nutrition at postoperative stage]. PMID- 4201334 TI - [Handling of an uncooperative child--communication with the patient following pharyngeal surgery]. PMID- 4201336 TI - [Fear of death and the attitude of the nurse]. PMID- 4201337 TI - [Nursing of a dying patient with pain]. PMID- 4201338 TI - [Expanding nursing function. Experience as a member of the Third Nursing Study Group visiting the United States]. PMID- 4201339 TI - [Statistics on the number of patients registered at the welfare establishments]. PMID- 4201340 TI - [Psychology of the aged and psychiatry]. PMID- 4201341 TI - [Sleep and insomnia]. PMID- 4201343 TI - [Starting point in the theory of assistance in nursing. 10. Re-evaluation of practical methods of assistance. (5)]. PMID- 4201342 TI - [Transfer technic. 3. Methods of turning the patient over]. PMID- 4201344 TI - [Psychology in human relationship in nursing. 10. Psychology of regression]. PMID- 4201345 TI - [Death and nursing. 10. Death and practice of nursing. Open channel of communication between the nurse and the patient]. PMID- 4201346 TI - [Medicine and civilization. 10. Male versus female]. PMID- 4201347 TI - Possible therapy in hereditary angioneurotic edema (HAE). PMID- 4201348 TI - [The method of methacrylate--embedding of corpuscular antigen in the immunofluorescence diagnosis of filariasis (author's transl)]. PMID- 4201349 TI - Cytological analysis of storage effects on various types of complete and mosaic change induced in drosophila chromosomes by some chemical mutagens. PMID- 4201350 TI - [Effect of alcohol on removal of lipids from plasma after hyperlipemic induced by a fatty meal or perfusion of lipid emulsions in man]. PMID- 4201351 TI - Recovery of the subhuman primate after deep cerebral hypothermia and prolonged ischaemia. PMID- 4201352 TI - Selective inactivation of the D or I forms of glycogen synthetase from rat skeletal muscle. PMID- 4201353 TI - [Psychological problems in the management of cancer patients]. PMID- 4201354 TI - [Resistance testing of the pathogens in urinary tract infections on agar dip slides]. PMID- 4201355 TI - Germination of actinomycete spores. PMID- 4201356 TI - Fibrinogen catabolism in Plasmodium knowlesi malaria. PMID- 4201357 TI - Survey of microsporidan hyperparasites of trematode larvae from Malaysian snails. PMID- 4201358 TI - Microdissection of scrub typhus vectors. PMID- 4201359 TI - Plaque formation in vero cell cultures by some Malaysian viruses. PMID- 4201360 TI - Microsporidian infection in Lymnaea rubiginosa. PMID- 4201361 TI - An orang asli blowpipe with a syringe-type dart for the liver capture of wild parimates in Malaysia. PMID- 4201362 TI - Simian neonatology. II. Neonatal pathology. PMID- 4201363 TI - Simian neonatology. 3. The causes of neonatal mortality. PMID- 4201364 TI - Mast cells and postnatal topographic anomalies in mammalian subfornical body and supraoptic crest. PMID- 4201366 TI - Protein-calorie malnutrition and intellect in childhood: A review. PMID- 4201365 TI - [Problems of protein metabolism in the intensive care of traumatology]. PMID- 4201367 TI - Bacterial pollution and disinfection of the colonofiberscope. II. Ethylene oxide gas sterilization. PMID- 4201368 TI - Hepatitis B. A study of 200 cases positive for the hepatitis B antigen. PMID- 4201369 TI - Bacterial pollution and disinfection of the colonofiberscope. I. An investigation of traditional sterilization methods. PMID- 4201370 TI - Epsilon-aminocaproic acid therapy in ulcerative colitis. PMID- 4201371 TI - Intramural diverticulosis of the esophagus. PMID- 4201372 TI - Effects of certain purified plasma proteins on the compatibility of glass with blood. AB - The effects of certain purified plasma proteins on the coagulation-activation and platelet-adhesion properties of glass surfaces have been investigated. Albumin, transferrin, gammaG globulin, gammaM globulin and fibrinogen were obtained in highly purified form; ceruloplasmin was a more crude preparation. Each of these proteins was found to adhere to glass surfaces and influence reactions of these surfaces with blood. gammaG globulin or albumin adsorbed to glass markedly inhibited activation of the intrinsic coagulation system, while the other proteins tested were much less effective in this respect. Fibrinogen, of all the proteins tested, greatly enhanced the adhesion of platelets to glass. Albumin, ceruloplasmin, transferrin, gammaG globulin and gammaM globulin each decreased the adhesion of platelets to glass by approximately 50%. Ultrastructural studies of the interface area where blood reacted with the layer of protein adsorbed to glass demonstrated the deposition of a moderately thick irregular protein layer upon the surface, with adhesion of cellular elements to this unilaminar adsorbed layer. Ultrastructural studies also demonstrated that platelets which adhere to protein-coated surfaces formed pseudopods and spread upon such surfaces. PMID- 4201375 TI - [Malignant catatonia. Treatment using hibernation]. PMID- 4201374 TI - Hereditary angio-neurotic oedema. Genealogical and immunological studies. PMID- 4201373 TI - Cultured skin fibroblasts in storage disorders. An analysis of ultrastructural features. AB - Electron microscopic studies were performed on cultured fibroblasts from patients with metachromatic leukodystrophy, Fabry's, Gaucher's, Niemann-Pick's (Type A and C), Sanfilippo's (Type A and B) disease, chondroitin-4-sulfate mucopolysaccharidosis, lipofuscinosis (Spielmeyer-Vogt's disease) and ceroid lipofuscinosis (Batten's disease with curvilinear bodies). Specific cytoplasmic inclusions with a limiting membrane were identified in Fabry's disease, Niemann Pick syndrome, chondroitin-4-sulfate mucopolysaccharidosis and Sanfilippo's Type B disease. In Fabry's disease, the lipid inclusions tended to form stacks of parallel and concentric membranes. In Niemann-Pick syndrome, the lipid inclusions were made of wavy, loosely packed membranes. In chondroitin-4-sulfate mucopolysaccharidosis and Sanfilippo B, the lysosomes were enlarged and contained a reticular matrix with little electron-dense material. No specific ultrastructural changes were observed in Gaucher's, Sanfilippo's (Type A) disease, metachromatic leukodystrophy (sulfatidosis) and Batten's disease. PMID- 4201376 TI - Presence of neutralizing antibody to canine distemper virus in sera of patients with subacute sclerosing panencephalitis. PMID- 4201377 TI - The nature and biological activity of IPN virus neutralizing antibodies in normal and immunized rainbow trout (Salmo gairdneri). PMID- 4201378 TI - [Radioimmunological determination of anti-D immunoglobulins]. PMID- 4201379 TI - Determination of polychlorinated biphenyl (Aroclor 1242) migration into food types. PMID- 4201380 TI - Polychlorinated terphenyls in the environment. PMID- 4201381 TI - Inhibition of aflatoxin and zearalenone biosynthesis with dichlorvos. PMID- 4201383 TI - Oxidation of polychlorinated biphenyls by achromobacter pCB. PMID- 4201382 TI - Oral toxicity of chlorinated dibenzofurans to juvenile Atlantic salmon. PMID- 4201384 TI - Determination of polychlorinated biphenyl (PCB's) residues in grades of pulp, paper and paperboard. PMID- 4201385 TI - Electron-capturing compounds and selected elements in paper. PMID- 4201386 TI - The occurrence of polychlorinated biphenyls (PCB's) in silage stored in pit and upright silos. PMID- 4201388 TI - Atypical diabetic coma. PMID- 4201389 TI - [Electrical response to nocuous stimulation and its inhibition in nucleus centralis lateralis of the thalamus in rabbits]. PMID- 4201387 TI - Whole body skeletal scintiphotography in the detection of occult metastatic breast carcinomas. AB - Whole body skeletal scintiphotography was carried out in a series of 111 breast cancer patients. The results of scintiphotography were compared with the results of roentgenography and with the diagnostic usefulness of serum alkaline phosphatase levels and the presence or absence of bone pain. In 27 percent of cases, lesions were first identified with the scintiphotos. When lesions were present on both scintiphotos and roentgenograms, involvement generally appeared greater on the scintiphotos. Two false negative studies were recorded. Sixty seven percent of patients with early metastasis-that is, those with positive scintiphotos and negative roentgenograms-were asymptomatic. Serum alkaline phosphatase levels were normal in 38 percent of those with early skeletal involvement. Skeletal scintiphotography is superior to other commonly employed techniques used to assess bone metastasis in breast carcinoma. PMID- 4201391 TI - [Electrophysiologic study of spinal reflexes under acupuncture anesthesia]. PMID- 4201390 TI - [Role of midbrain reticular formation in acupuncture anesthesia]. PMID- 4201392 TI - [Effect of needling positions in acupuncture on pain threshold of human skin]. PMID- 4201393 TI - [Successful resuscitation of 12 cases of circulatory arrest lasting over 8 minutes]. PMID- 4201394 TI - [Ultrasound cardiography in the diagnosis of mitral insufficiency]. PMID- 4201395 TI - [Relationship between blood vessels and osteogenesis during fracture healing]. PMID- 4201396 TI - [Pharmaceutical studies of an antidiphtheria preparation]. PMID- 4201398 TI - [Cryptococcus neofromans meningitis]. PMID- 4201397 TI - [Survey on health hazards in argon-arc welding]. PMID- 4201399 TI - IgG-1(kappa) M component after bone marrow transplantation. PMID- 4201400 TI - Biosynthesis of the fifth component of complement (C5) by human fetal tissues. PMID- 4201401 TI - Antinuclear antibodies and nuclear antigens in rheumatoid synovial fluids. PMID- 4201403 TI - Thirty-two fatal cases of severe diabetic ketoacidosis, including a case of mucormycosis. PMID- 4201404 TI - [Pancreatic factors in the pathogenesis of ulceration]. PMID- 4201402 TI - Generation of chemotactic factors in guinea pig serum via activation of the classical and alternate complement pathways. PMID- 4201406 TI - [Antral ring: unusual anomaly (description of a case)]. PMID- 4201405 TI - [Upper gastrointestinal hemorrhages]. PMID- 4201407 TI - Tubeless hypotonic duodenography. PMID- 4201409 TI - Experimental allergic uveitis. Studies on characterization and isolation of the pathogenic retina antigen. PMID- 4201408 TI - Protective role of prednisolone upon galactosamine-induced hepatitis in rats. PMID- 4201410 TI - Serological studies of Haemophilus influenzae. IV. The antibody response in rabbits against capsular and O antigens of H. influenzae. PMID- 4201411 TI - Tubular lesions produced by autoantibodies to tubular basement membrane in human renal allografts. PMID- 4201412 TI - Leucocyte migration inhibition to Mycoplasma fermentans in patients with rheumatoid arthritis. PMID- 4201413 TI - Inhibition of allergic reactions by cromoglycate and by AH 7079 in patients with allergic airway disease. PMID- 4201414 TI - The effect of hypoxia on radiation life-shortening in Drosophila melanogaster. PMID- 4201415 TI - The location of antibacterial activity in the rat prostatic secretions. PMID- 4201416 TI - Inhibition of bacterial urease. PMID- 4201417 TI - Prolactin and growth hormone release in response to sequential stimulation by arginine and synthetic TRF. PMID- 4201418 TI - Alpha chain of glycoprotein hormones: presence in human serum after thyroid stimulating hormone releasing hormone. PMID- 4201419 TI - Ultrastructure of giant pigment granules (macromelanosomes) in the cutaneous pigmented macules of neurofibromatosis. PMID- 4201420 TI - Oxidation of furans. 2. Synthesis and biological properties of 6-hydroxy-2H-pyran 3(6H)-ones and derivatives. PMID- 4201422 TI - Synthesis of the thyrotropin-releasing hormone enantiomer and some diastereoisomers and in vitro studies of their biological activity. PMID- 4201421 TI - In vivo metabolite condensations. Formation of N1-ethyl-2-methyl-N3-(2,6 dimethylphenyl)-4-imidazolidinone from the reaction of a metabolite of alcohol with a metabolite of lidocaine. PMID- 4201423 TI - Synthesis of antimicrobial nitroimidazolyl 2-sulfides, -sulfoxides, and sulfones. PMID- 4201424 TI - Methotrexate analogs. 2. A facile method of preparation of lipophilic derivatives of methotrexate and 3',5'-dichloromethotrexate by direct esterification. PMID- 4201426 TI - Prevention and mitigation of head injury from antiquity to the present. PMID- 4201425 TI - Cordycepin and alpha-amanitin: inhibitors of transcription as probes of aldosterone action. PMID- 4201427 TI - The mechanism of injury in blunt abdominal trauma. PMID- 4201428 TI - Defective hemoglobin function: a complication of hyperalimentation. PMID- 4201430 TI - Response to thyrotropin-releasing hormone compared with thyroid suppression tests in euthyroid Graves' disease. PMID- 4201429 TI - Lung transplantation: a review of its current studies. PMID- 4201432 TI - Alpha-fetoprotein in Rh-immunized pregnancies. PMID- 4201431 TI - Evolution of 5S RNA and the non-randomness of base replacement. PMID- 4201433 TI - Studies on the division cycle of mammalian cells. VII. X-ray sensitivity and repair capacity of synchronously dividing murine mastocytoma cells. PMID- 4201434 TI - X-ray-induced alterations in marker replication pattern in Bacillus subtilis W23. PMID- 4201435 TI - Sudanophilic lipids in the unmyelinated primate cerebral white matter after intrauterine hypoxia and acidosis. PMID- 4201436 TI - The role of ontogeny in the establishment of species-specific patterns. PMID- 4201437 TI - [Salmonella in animals purchased for experimental studies (author's transl)]. PMID- 4201438 TI - Delay in the onset of immune hemolysis in vivo apparently due to heparinization. PMID- 4201439 TI - Fetal cell counting as a guide to prevention of Rh sensitization. PMID- 4201440 TI - Laser flash photolysis studies of chlorin and porphyrin systems. I. Energetics of the triplet state of bacteriochlorophyll. PMID- 4201441 TI - Effects of measles on the immune response of Nigerian children. PMID- 4201442 TI - Proceedings: Treatment of perennial childhood asthma. PMID- 4201443 TI - Proceedings: Control of infection in children with leukaemia and lymphomas. PMID- 4201444 TI - Treatment of chronic urinary tract infection in children. I. Propicillin dicloxacillin combination for Pseudomonas aeruginosa infections. PMID- 4201446 TI - Letter: Monkeys for research. PMID- 4201445 TI - Phosphorylase and glycogen synthetase during myoblast differentiation. PMID- 4201447 TI - Structural studies on the specific capsular polysaccharide from Rhizobium trifolii, TA-1. PMID- 4201448 TI - The preparation and biological activity of novel amino acid analogs of butirosin. PMID- 4201449 TI - Granulomatous bacterial arthritis. PMID- 4201451 TI - Antibiotics. An overview. PMID- 4201450 TI - The open fracture. Cause, effect and management. PMID- 4201452 TI - Comparison of gram-negative bacillary and staphylococcal osteomyelitis of the femur and tibia. PMID- 4201453 TI - [Protein-calorie malnutrition and child health]. PMID- 4201454 TI - Australia antigen in professional blood donors and student volunteers at Poona. PMID- 4201455 TI - A comparison of the fluorometric and microbiological assays for estimating riboflavin content of blood and liver. PMID- 4201456 TI - Acute severe insulin resistance. A case report. PMID- 4201457 TI - [Mathematical analysis of the results of whole body radiometry]. PMID- 4201458 TI - [Graphical approximation of curves of whole body and separate organs radioactivity]. PMID- 4201459 TI - [Simultaneous determination of renal function by means of EDTA-Yb 169 and hippurane I-131]. PMID- 4201460 TI - [Relative biological efficiency of mixed high energy electron and breaking radiation (Bremsstrahlung)]. PMID- 4201461 TI - A theoretical EHT study of structure-activity relationships in a series of sulfonamides. PMID- 4201462 TI - [Importance of serum properties in the absorption-elution reaction for detecting the D antigen of the Rh system]. PMID- 4201464 TI - Blood group mosaicism involving the rhesus and Duffy blood groups. PMID- 4201463 TI - Identification and clinical implications of isoantibodies in patients with idiopathic dysgammaglobulinemia. PMID- 4201465 TI - Three examples of Rh-positive, good responders to blood group antigens. PMID- 4201466 TI - Eye diseases in two families of animals. PMID- 4201467 TI - Undernutrition. PMID- 4201468 TI - Nutrition and behavior and learning. PMID- 4201469 TI - Nutrition and disease. PMID- 4201471 TI - [Formation of spores in growing Bacillus subtilis cultures and their correlation with competence for genetic transformation]. PMID- 4201470 TI - Degradation of progesterone by aspergilli-side chain cleaving enzymes. PMID- 4201472 TI - Two different patterns of segmentation in eggs of Bufo arenarum. PMID- 4201473 TI - Radiation induced pericarditis in Hodgkin's disease. PMID- 4201475 TI - Electron irradiation of monkey skin. PMID- 4201474 TI - Behaviour of intravenously injected 51CrCl3 in irradiated and nonirradiated mice. PMID- 4201476 TI - Distribution of 226Ra in the bones of mice. PMID- 4201477 TI - Gold in the dermis following gold therapy for rheumatoid arthritis. PMID- 4201478 TI - Diagnosis of deep infection with Candida. A study of Candida precipitins. PMID- 4201479 TI - Heparin sensitivity. Report of a case. PMID- 4201481 TI - [Microbial toxins and intercellular contact in vitro. The role of thermostable and thermolabile endotoxins of Salmonella typhimurium S]. PMID- 4201480 TI - [An experimental model of intercellular contact. I. Use of phytohemagglutinins as a blastogenic agent]. PMID- 4201482 TI - Dispersal activities of the sibling species Drosophila melanogaster and Drosophila simulans. PMID- 4201484 TI - [Effects of carbon dioxide anesthesia in Drosophila: distention of the digestive tube and mortality of young adults]. PMID- 4201483 TI - The chemical composition and serological reactions of lipopolysaccharides from serogroups A,B,X, and Y Neisseria meningitidis. PMID- 4201485 TI - Hepatitis B antigen: distribution of ad and ay subtypes in blood donors and hepatitis patients. AB - Hepatitis B antigen (HBAg) from blood donors and patients with hepatitis was tested for ad and ay subspecificity by immunodiffusion in agarose. A total of 59 sera from blood donors and 81 sera from hepatitis patients were subtyped.Subtyping of HBAg from blood donors showed ad and ay subspecificity in 64.4 and 35.6% of cases respectively. Patients' sera on the other hand showed HBAg with ad and ay subspecificity in 6 and 94% of cases respectively. Therefore, ad subtype was more frequently associated with blood donors whereas ay subtype was predominant among hepatitis patients. The relationship between clinical findings and HBAg subtype is also discussed. PMID- 4201486 TI - [Etiopathogenesis of chronic pancreatitis]. PMID- 4201487 TI - Editorial: In pursuit of Pneumocystis carinii. PMID- 4201488 TI - [Treatment of acquired megacolon in adults. Considerations on Duhamel's technic with perineal colostomy]. PMID- 4201489 TI - The extensor assembly of Saimiri sciurea. PMID- 4201490 TI - A logic to long-term care. PMID- 4201491 TI - Community care for the elderly: an alternative to institutionalization. PMID- 4201492 TI - Genetical study of Angami Nagas (Nagaland, India): A1A2BO, MN, Rh blood groups, ABO(H) secretion, PTC taste sensitivity and colour-blindness. PMID- 4201493 TI - Further studies on genetically mediated differences in monooxygenase activities and spin state of cytochrome P450 iron from rabbit, rat, and mouse liver. PMID- 4201495 TI - Calorimetric studies of thymidylate synthesis. PMID- 4201494 TI - Further genetic and enzymological characterization of the three Bacillus subtilis deoxyribonucleic acid polymerases. PMID- 4201496 TI - Polymorphism of Rhesus monkey serum prealbumin. Purification and partial structure. PMID- 4201497 TI - The effects of modification of the COOH-terminal regions of bovine thyrotropin and its subunits. PMID- 4201498 TI - The effects on rabbits of immunization with bovine thyroid-stimulating hormone and its subunits. AB - Rabbits were immunized with bovine thyroid-stimulating hormone (bTSH), bovine Inteinizing hormone (bLH), and their subunits. In two immunization experiments, thyroid-stimulating activity was found in the serum of 6 out of 12 rabbits immunized with bTSHbeta subunits. The thyroid-stimulating activity in the anti bTSHbeta sera was greater at 2 h than at 8, was eluted with the globulin fraction from Sephadex G-100, was completely neutralized by both anti-bTSH and anti-rabbit gamma globulin, and was completely suppressed by administration of triiodothyronine (T(3)) to the immunized rabbit. These findings led to the conclusion that the thyroid-stimulating activity resided in soluble complexes of rabbit TSH bound to anti-bTSHbeta. Two of nine rabbits immunized with bTSH developed thyroid-stimulating activity in their serum, but it was nonsuppressible by T(3). None of the animals immunized with bTSHalpha, bLH, bLHbeta, or bLHalpha developed serum thyroid-stimulating activity.Hypopituitary hypothyroidism, evidenced by decreased serum thyroxine (T(4)) and thyroidal (131)I uptake and by the histologic appearance of large follicles with flat cells, was found in the bTSHbeta- and bTSH-immunized animals, despite the presence of thyroid-stimulating activity in the serum of many. The reasons for this paradox are unclear; possibly the complexes block the effect of TSH on the rabbit thyroid. PMID- 4201499 TI - B lymphocytes in untreated patients with malignant lymphoma and Hodgkin's disease. AB - B and T lymphocytes in 37 untreated patients with malignant lymphoma and Hodgkin's disease were studied. B cells in the peripheral blood were investigated with respect to surface immunoglobulins and in a few patients with respect to intracytoplasmic immunoglobulins by means of immunofluorescence. T cell function was studied by direct phytohemagglutinin (PHA) microtest (from the same sample of whole blood), mixed lymphocyte culture (MLC), and by delayed hypersensitivity to various antigens. In the 13 patients with Hodgkin's disease the histologic subtype was nodular sclerosis in nine, lymphocyte predominant in two, mixed cellularity in two. Only one of these patients had disseminated disease (stage IV); he showed impaired cellular immunity, a very low percentage of B cells and low levels of serum immunoglobulins. Of the remaining patients with Hodgkin's disease, with one exception, normal percentages but rather low absolute numbers of B lymphocytes per mm(3) of blood were found. One patient with a low percent and low absolute number of B lymphocytes showed very high serum IgG. Of 24 patients with non-Hodgkin's malignant lymphoma, seven (29%) showed monoclonal B cell proliferation in the peripheral blood (five mukappa, two gammakappa). By morphologic criteria, 14 patients had involvement of bone marrow, five of these had involvement of peripheral blood. Four of the latter five patients showed marked increases in percentages and absolute numbers of B lymphocytes in the peripheral blood reflecting the monoclonal proliferation. In three additional patients monoclonal proliferation of lymphocytes was found by immunofluorescence although the blood smears appeared morphologically normal. Serum immunoglobulin abnormalities without monoclonal B cell proliferation in the peripheral blood were observed in six patients. PMID- 4201502 TI - Medical education and medical care. Problems at the interface. Urban problems: Social Security and the teaching hospital. PMID- 4201500 TI - Characterization of ileal vitamin B12 Binding using homogeneous human and hog intrinsic factors. AB - Elucidation of the mechanism of intrinsic factor (IF)-mediated vitamin B(12) (B(12)) binding to ileal binding sites has been hampered by the use of crude or only partially purified preparations of IF in previous studies. We have used homogeneous human IF and hog IF isolated by affinity chromatography to study [(57)Co]B(12) binding to ileal mucosal homogenates. The following observations were made: (a) Human IF-B(12) and hog IF-B(12) were bound to human, monkey, hog, dog, rabbit, mouse, hamster, and guinea pig ileal, but not jejunal, homogenates in amounts significantly greater than free B(12) or B(12) bound to five other homogeneous B(12)-binding proteins; (b) only IF-mediated B(12) binding was localized to ileal homogenates and was inhibited by EDTA; (c) values for the association constant (K(a)) for the various ileal homogenates mentioned above and human IF-B(12) and hog IF-B(12) ranged from 0.3 x 10(9) M(-1) to 13.0 x 10(9) M( 1). Apparent differences in the K(a) for human IF-B(12) and hog IF-B(12) existed in most species; (d) the number of ileal IF-B(12) binding sites per gram (wet weight) of ileal mucosa ranged from 0.3 x 10(12) to 4.9 x 10(12). The same value was always obtained with human IF-B(12) and hog IF-B(12) for any given homogenate preparation; (c) 100-fold excesses of free B(12) or human IF and hog IF devoid of B(12) did not significantly inhibit human IF-B(12) and hog IF-B(12) binding to human and hog ileal homogenates. THESE EXPERIMENTS PERFORMED WITH HOMOGENEOUS IF INDICATE THAT: (a) gastric factors other than IF are not required for B(12) binding to ileal IF-B(12)-binding sites: (b) the mechanism of ileal IF-B(12) binding is different from that of free B(12) or of B(12) bound to non-IF-B(12) binding proteins; (c) human IF and hog IF have different structures; (d) human IF B(12) and hog IF-B(12) bind to the same ileal binding sites; and (c) human and hog ileal IF-B(12) binding sites bind free B(12) and human and hog IF devoid of B(12) poorly, if at all. PMID- 4201501 TI - Detection of fibrinogen antigens with two latex techniques applied to urine concentrates. AB - Fibrinogen antigens were measured either with an agglutination inhibition method (using latex particles coated with fibrinogen; Diagen test) or with a direct agglutination technique (using latex particles coated with a mixture of anti-D and anti-E antibodies; Thrombo-Wellcotest). Both methods were compared with the tanned red cell haemagglutination inhibition immunoassay (TRCHII) during progressive degradation of fibrinogen with plasmin and using purified fibrinogen fragments or urine concentrates from chronic glomerulonephritis or transplanted patients. Due to the different sensitivity of the two latex techniques to fibrinogen and its plasmin derivatives, their combined use may be helpful to distinguish the nature of the fibrinogen-like material excreted in urine. PMID- 4201503 TI - Medical education and medical care in Puerto Rico. PMID- 4201504 TI - The localization of calcium in skeletal muscle: its distribution in muscles in which the caffeine-induced contracture was arrested. PMID- 4201505 TI - Relapsing form of subacute necrotizing encephalomyelopathy. PMID- 4201506 TI - [Studies on the problem of determining the functional conditions of kidneys preserved by hypothermic perfusion: animal experiments by means of radioisotopes procedures (author's transl)]. PMID- 4201507 TI - Intestinal resorption of gold salts used for treatment of rheumatoid arthritis. PMID- 4201508 TI - Direct evidence for a colchicine-induced impairment in the mobility of membrane components. AB - Freeze-etch electron microscopy was used to show that colchicine interacts with membranes of the ciliate protozoan Tetrahymena pyriformis. Colchicine impairs the temperature-induced translational and vertical mobility of the membrane intercalating particles of the freeze-fractured alveolar membranes lying just below the plasma membranes. PMID- 4201509 TI - [Pharmacokinetics, drug availability and clinical pharmacology of bromhexine]. PMID- 4201510 TI - [Euglucon in ambulatory practice]. PMID- 4201511 TI - Determination of carbonic anhydrase (E.C. 4.2.1.1.) activity by means of the pH stat-technique. PMID- 4201512 TI - [Simplified photometric determination of calcium in serum without deproteinisation (author's transl)]. PMID- 4201513 TI - Immunological investigations into the causes of aspecific ABR-reactions. PMID- 4201514 TI - Human meningoencephalitis caused by the free-living amoebae. PMID- 4201515 TI - Mouth care. PMID- 4201516 TI - Under the cover of his charm. PMID- 4201517 TI - A nurse for all reasons. PMID- 4201518 TI - Aegyptopithecus endocasts: oldest record of a pongid brain. PMID- 4201519 TI - Semi-natural and enclosed groups of Macaca mulatta: a behavioral comparison. PMID- 4201520 TI - Small analytical BD-cellulose columns for rapid chromatography of aminoacyl tRNAs. PMID- 4201521 TI - A rapid electrophoretic procedure for the detection of SDS-released oncorna-viral RNA using polyacrylamide-agarose gels. PMID- 4201522 TI - [Tuberculosis-specific antibodies in skeletal tuberculosis]. PMID- 4201524 TI - Isozyme variability in species of the genus Drosophila. VII. Genotype-environment relationships in populations of D. melanogaster from the Eastern United States. PMID- 4201523 TI - Glucose 6-phosphate dehydrogenase from brook, lake, and splake trout: an isozymic and immunological study. PMID- 4201526 TI - Regulation of phenylalanine biosynthesis in Pseudomonas aeruginosa. PMID- 4201527 TI - The sialic acids of toad oviduct mucoprotein. PMID- 4201525 TI - Comparative analysis of malate dehydrogenases of Drosophila melanogaster. PMID- 4201528 TI - Metabolism of sialic acids in toad oviduct. PMID- 4201529 TI - The production and purification of specific anti-soybean agglutinin antibody by affinity chromatography. PMID- 4201530 TI - Phosphotransacetylase from Bacillus subtilis: purification and physiological studies. PMID- 4201531 TI - Study of correlation between structural motility and reactivity of SH groups in alpha-amylase. PMID- 4201532 TI - Pig kidney particulate aminopeptidase. A zinc metalloenzyme. PMID- 4201533 TI - Acetolactate synthase of Pseudomonas aeruginosa I. Purification and allosteric properties. PMID- 4201535 TI - [Simultaneous study of circadian variations of blood thyrotropin (TSH) and pituitary prolactin levels in man]. PMID- 4201534 TI - Acetolactate synthase of Pseudomonas aeruginosa. II. Evidence for the presence of two nonidentical subunits. PMID- 4201536 TI - [Effect of 2-Br-alpha-ergocryptine (CB 154) on the secretion of prolactin in Anguilla]. PMID- 4201537 TI - [Fatty acid composition of plasma AGT and AGN in rats on diets containing 15 per cent by weight of various oils for 3 days since weaning. Effects of fasting and lipotropic substances. Comparison between plasma, liver, and myocardium]. PMID- 4201538 TI - [Pachypodol (5,4'-dihydroxy 3,7,3'-trimethoxy flavone or 3,7,3'-quercetol trimethylether), a new flavonoid isolated from Pachypodanthium confine Engler and Diels (annonaceae)]. PMID- 4201539 TI - [Inhibitory action of Corynebacterium parvum on the development of malignant syngenic tumors, and its mechanism]. PMID- 4201540 TI - [Selection of dominant mutants of the influenza A (Hong Kong) virus by immunological pressure]. PMID- 4201541 TI - [Systems of genome transcription in adenovirus. Enzymatic activity of extracts containing nuclear RNA polymerases of KB cells infected by adenovirus 2]. PMID- 4201542 TI - [Effect of repeated x-ray doses on survival and DNA synthesis in human cancer explants maintained in long-term organotypic culture]. PMID- 4201543 TI - Haloperidol in the treatment of nausea and vomiting due to cytotoxic drug administration. PMID- 4201545 TI - Nitroglycerin: clinical pharmacological effects of form and route of administration. PMID- 4201544 TI - Anxiolytic effects of a new triazolobenzodiazepine, U-31,889. PMID- 4201546 TI - Clindamycin palmitate hydrochloride: a clinical trial in a pediatric office practice. PMID- 4201547 TI - Treatment of acute hypercalcemia with furosemide. PMID- 4201548 TI - Double-blind study of acetylcysteine-isoproterenol and saline-isoproterenol in non-hospitalized patients with asthma. PMID- 4201549 TI - Influence of intravenous administration of hypertonic solution on pain sensibility. PMID- 4201550 TI - Comparison of various precipitin tests in the detection of alpha-fetoprotein in serum. PMID- 4201551 TI - Macrophage-mediated resistance to intracellular infection induced by poly-L glutamic acid. PMID- 4201552 TI - The stoichiometry of J chain in human secretory IgA. PMID- 4201553 TI - Recombination of the polypeptide chains of a Waldenstrom's IgM that binds IgG. PMID- 4201554 TI - Migration inhibition of rat peritoneal cells induced by streptococcal mucopeptides. Characteristics of the reaction and properties of the mucopeptide preparations. PMID- 4201555 TI - Quantitative phagocytosis by neutrophils. I. A new method with immune complexes. PMID- 4201556 TI - Quantitative phagocytosis by neutrophils. II. Release of the C5-cleaving enzyme and inhibition of phagocytosis by rheumatoid factor. PMID- 4201557 TI - Human antibody to dengue soluble complement-fixing (SCF) antigens. PMID- 4201558 TI - Isolation of mucin from human submaxillary secretions. PMID- 4201560 TI - Inversion injuries of the ankle. PMID- 4201559 TI - Rosette formation by guinea pig thymocytes and thymus derived lymphocytes with rabbit red blood cells. PMID- 4201561 TI - Diverticula of the appendix. PMID- 4201562 TI - Renal failure associated with the use of thio-tepa. PMID- 4201563 TI - [Rectoscopy as a preventive measure?]. PMID- 4201564 TI - [Hypophyseal-gonadal regulation in patients with chronic kidney failure during long-term dialysis]. PMID- 4201565 TI - Effect of osmotic concentration and pH on sclerotia and cleistothecia production in alkaline and fertile soil Aspergilli. PMID- 4201566 TI - [Lipids and arteriosclerosis]. PMID- 4201567 TI - [Studies on trypanosomiasis in Zacatecas. I. A further typical case of acute Chagas' disease in Tepechitlan]. PMID- 4201569 TI - [Epilepsy and choreo-athetosis in a monkey (Erytrocebus Patas) with diffuse disorder of basal ganglia]. PMID- 4201568 TI - [Tosoplasmosis. Study in human serums in the last 4 years. Comparison between the serology of toxoplasmosis and infection by Sarcocystis in cattle]. PMID- 4201570 TI - Cholesterol gallstones. PMID- 4201571 TI - The role of computers in the nuclear medicine laboratories. PMID- 4201572 TI - Whole-body counting. PMID- 4201573 TI - Acute diverticulitis. PMID- 4201574 TI - The outcome of stroke at hospital discharge in New York City blacks. PMID- 4201575 TI - Safety tests of orgotein, an antiinflammatory protein. PMID- 4201576 TI - An attempt to classify the toxic proteins of Elapidae and Hydrophiidae venoms. PMID- 4201577 TI - [The concentration of cholesterol in the serum of blood flowing from the brains of patients with cranio-cerebral trauma]. PMID- 4201578 TI - [Therapy of acute leukoses]. PMID- 4201579 TI - [Simple method for selective culturing of Listeria monocytogenes]. PMID- 4201580 TI - [Method for determination of blood sedimentation time in undiluted venous blood with use of ethylenediamine tetracetic acid (EDTA)]. PMID- 4201581 TI - On the natural history of coccidial infections in feeder cattle. PMID- 4201582 TI - Australia antigen and circulating antibodies in chronic aggressive hepatitis. PMID- 4201583 TI - Influence of fixation on physiological properties of frog gastric mucosa. PMID- 4201584 TI - Metabolism of 14C-histamine in goats and pigs treated with aminoguanidine. PMID- 4201585 TI - On the elimination of transfused heparin-induced diamine oxidase (DAO) activity in rabbits. PMID- 4201586 TI - Effect of organ removal or damage on the heparin-induced diamine oxidase (DAO) response in rat and rabbit. PMID- 4201587 TI - Application of gas chromatography, mass spectrometry, and computer methods in clinical biochemistry. PMID- 4201588 TI - Studies on the methylation of mercuric chloride by pure cultures of bacteria and fungi. PMID- 4201589 TI - [Morphological changes in monkey vessels (baboons and macaques) during feeding of rations with cholesterol]. PMID- 4201590 TI - Monomolecular films of bacteriochlorophyll and derivatives at an air-water interface: surface and spectral properties. PMID- 4201591 TI - [Effect of carbon-containing compounds on the chromatic characteristics of Anacystis nidulans blue-green algae]. PMID- 4201592 TI - [Effect of seven on the Mongolian tree creeper]. PMID- 4201593 TI - Disposition of arabinosylcytosine (NSC-63878) and 6-THIOGUANINE (NSC-752) in solid L1210 leukemia tumor-bearing mice. PMID- 4201594 TI - Mucolipidosis 3 (pseudo-Hurler polydystrophy): cytological and ultrastructural observations of cultured fibroblast cells. PMID- 4201595 TI - Relief of musculoskeletal and associated psychopathological symptoms with meprobamate and aspirin: a controlled study. PMID- 4201596 TI - Controlled evaluation of a new topical corticosteroid in psoriasis. PMID- 4201597 TI - A double-blind comparison of active and inert douches in vaginitis. PMID- 4201598 TI - Diazepam (calmpose) in eclampsia: a preliminary report of 16 cases. PMID- 4201599 TI - Safety and effectiveness of haloperidol for mentally retarded behaviorally disordered and hyperkinetic patients. PMID- 4201600 TI - The effect of lithium and other antidepressant medications on the autonomic nervous system. PMID- 4201601 TI - Serum levels of anhydrous ampicillin administered orally in normal infants. PMID- 4201602 TI - [Antigenic divergence in the Canidae family observed using rabbit antiserum to blood serum of the fox (Vulpes fulvus)]. PMID- 4201603 TI - [Role of projection and association areas of the cerebral cortex in the organization of sensory input to the monkey caudate nuclei]. PMID- 4201604 TI - [Pituitary TSH releasing capacity in the aged]. PMID- 4201605 TI - [Biological fate of thyrotropin-releasing hormone (TRH)]. PMID- 4201606 TI - [Total and free serum thyroxine and triiodothyronine levels and the effect of estrogen in a family with thyroxine-binding globulin deficiency]. PMID- 4201607 TI - [Effects of synthetic TRH on human prolactin (HPr) secretion]. PMID- 4201609 TI - Studies of Anatrichosoma (Nematoda: Trichinellida) with descriptions of Anatrichosoma rhina sp. n. and Anatrichosoma nacepobi sp. n. from the nasal mucosa of Macaca mulatta. PMID- 4201610 TI - Advances in radiotherapy--improved results following treatment with high energy electrons and 25 MEV X-ray. 1. PMID- 4201608 TI - [Intrauterine nutrition of the malnourished fetus. Autoradiographic demonstration of intra-amniotically administered amino acids. Experimental studies]. PMID- 4201611 TI - An improved method for the scanning electron microscopy of spermatozoa. PMID- 4201612 TI - Metabolic profile of a new immunosuppressive agent, oxisuran: binding, RE stimulation, drug interaction. PMID- 4201614 TI - [EEG findings in Turner's syndrome]. PMID- 4201613 TI - Diffusive and electrostatic effects with insolubilized enzymes subject to substrate inhibition. PMID- 4201615 TI - [Infection resistance in rickets]. PMID- 4201616 TI - [Blood coagulation parameters and platelet functions before and after exchange transfusion in newborn infants]. PMID- 4201617 TI - [Effect of probenecid in penicillin therapy]. PMID- 4201618 TI - Near-cytotoxic gold salt therapy in long standing drug-refractory rheumatoid arthritis. A prospective investigation. PMID- 4201619 TI - Development of nonspecific factors of antiinfection resistance of monkeys in ontogenesis. PMID- 4201620 TI - Beta-fetoprotein as a thymus-dependent factor in humans. PMID- 4201621 TI - [Phenytoin-induced folic acid deficiency]. PMID- 4201622 TI - [Complex conservative therapy of urinary incontinence in elderly woman with ubretid, oestriol and gymnastic exercises (author's transl)]. PMID- 4201623 TI - A qualitative demonstration of the degradation of folic acid by Pseudomonas fluorescens UK-1. PMID- 4201624 TI - Antigenic relationship between lysozymes and its use in isolation and purification of this type of enzyme. PMID- 4201625 TI - [Co-trimoxazole in urinary infections. Comparative double-blind study with an antibiotic]. PMID- 4201626 TI - Cartilaginous transformation of the aortic valve. PMID- 4201627 TI - Fibrin degradation products in the postoperative period. Evaluation of a new latex agglutination method. PMID- 4201628 TI - Endocarditis caused by Bacillus subtilis. PMID- 4201629 TI - Studies on the variables in Rh slide testing. PMID- 4201630 TI - Miliary tuberculosis. PMID- 4201631 TI - Clinical significance of casual isolation of acid-fast organisms from sputum of tuberculous patients. PMID- 4201632 TI - Studies on the bacteriophage of a natural lysogenic Mycobacterium fortuitum. PMID- 4201633 TI - Letter: Correlation of lymphocyte transformation with tuberculin skin-test sensitivity. PMID- 4201634 TI - Pseudomonas aeruginosa resistant to carbenicillin and gentamicin. Epidemiologic and clinical aspects in a cancer center. PMID- 4201635 TI - Tropical problems in nutrition. PMID- 4201636 TI - Urate secretion in man: the pyrazinamide suppression test. PMID- 4201637 TI - Neisseria gonorrhoeae auxotyping: differentiation of clinical isolates based on growth responses on chemically defined media. AB - A system is described for differentiating clinical isolates of Neisseria gonorrhoeae based on their growth or absence of growth on a set of 11 chemically defined agar media. The complete medium, NEDA, contains all of the compounds required for gonococcal growth; but isolates differ in their ability to grow on NEDA from which selected compounds are individually omitted. The differential compounds include L-proline, L-arginine, L-ornithine, L-methionine, hypoxanthine, uracil, thiamine, and thiamine pyrophosphate. A distinctive pattern of growth responses on the standard media defines an auxotype. Twenty auxotypes were found among a group of 251 gonococci which were isolated from patients examined in the clinics of one city during a 3-month span of time. Another collection of 74 strains from several different countries yielded two additional auxotypes. The stability of the nutritional requirements on which the auxotyping depends was verified in two ways. Cultures isolated from different anatomic sites of a patient or from sexual partners represented the same auxotype, as did cultures which were repeatedly isolated from cases of presumptive treatment failures. Also, the auxotypes of gonococci remained the same after numerous subcultures. The reproducibility of results and the variety and number of auxotypes indicate the potential value of the auxotyping system as an epidemiological tool. PMID- 4201639 TI - Specific immunodiffusion test for blastomycosis. AB - A specific immunodiffusion test for blastomycosis has been developed. The test permitted the detection of approximately 80% of 113 proven cases of blastomycosis. Two diagnostically important precipitins designated A and B were frequently recognized in patients with blastomycosis. Routine use of reference sera containing the A and B precipitins in immunodiffusion tests would permit the specific diagnosis of blastomycosis without the need for parallel tests with coccidioidin and histoplasmin. PMID- 4201638 TI - Detection and identification of diagnostic Histoplasma capsulatum precipitates by counterelectrophoresis. AB - Studies were carried out to develop and evaluate a counterelectrophoresis (CEP) technique for the rapid and specific identification of the diagnostically important histoplasmosis H and M precipitin bands. Well-defined and centrally located precipitin bands were produced by using a discontinuous buffer system and a gel matrix composed of agarose and ionagar no. 2. A template was devised which allowed the selective identification of the H and M precipitins. Comparative evaluations were performed with the microimmunodiffusion (ID) and complement fixation tests. In 52 sera from persons with histoplasmosis, either the H or M precipitin, or both, were identified in 42 (81%) of the cases with the CEP technique and in 43 (83%) with the ID test. With sera from 28 persons with heterologous diseases, the CEP technique, like the ID test, failed to react. The specificity of the CEP technique was dependent upon the use of the identity template. The CEP technique is recommended for routine use in laboratories testing moderate numbers of sera. It provides accurate and reproducible results within 90 min, in contrast to the ID test, which requires 18 to 24 h. PMID- 4201640 TI - Variation in colonial morphology of Neisseria gonorrhoeae after growth on media containing antimicrobial agents. AB - Stable colonial types 1, 2, 3, and 4 were prepared from eight strains of Neisseria gonorrhoeae. Four of the strains, termed laboratory strains, had been transferred over 100 times; three strains, termed clinical strains, were transferred only three to five times after isolation from patients, and one stabilized clinical strain was transferred purposefully 30 times after isolation from a patient. Colonial types of the three categories were grown on four media containing the following agents at the level used in diagnostic media: (i) vancomycin, colistin, and nystatin; (ii) these antibiotics plus trimethoprim lactate; (iii) trimethoprim lactate alone; and (iv) a control with no antimicrobial agents. When grown on media containing the antimicrobial agents, colonial types 1, 2, and 3 of all strains showed specific and consistent changes that precluded accurate identification of the types. In general, the colonies were smaller, more dense to transmission of light, and more granular than colonies grown on control medium. More colonies showed these type changes in the clinical strains and on media containing trimethoprim lactate. Colonies of type 4 showed little or no change. The changes in colonial morphology of types 1, 2, and 3 were pronounced enough to make colony typing difficult if the antimicrobial agents, particularly trimethoprim lactate, were present in media. PMID- 4201641 TI - In vitro studies with Modoc virus in Vero cells: plaque assay and kinetics of growth, neutralization, and thermal inactivation. AB - A sensitive and quantitative assay system is described for plaquing Modoc virus in Vero cells. Neutralizing antibodies to Modoc virus could be detected by using this in vitro system by their interference with viral plaque formation. Virus was readily neutralized within 30 min at 37 C by a 1:10 dilution of hyperimmune hamster serum. The rate of neutralization and the total amount of virus neutralized was not altered significantly by the addition of 20 U of guinea pig complement to the hyperimmune hamster serum. A study of the growth of Modoc virus in Vero cells is also presented. After an initial latent period of 20 h, viral titer increased exponentially for 20 h. By 83 h after infection, 8,000 plaque forming units of virus were detected per cell. The stability of viral infectivity in phosphate-buffered saline at pH 7.4 was evaluated. No reduction in viral titer was detected after 3 days at 7 or 22 C. A continuous decrease in infectivity at 37 C was observed, however, throughout the observation period. PMID- 4201642 TI - Microtissue culture plaque assay for Herpesvirus saimiri. AB - A microtissue culture method for the plaque assay of Herpesvirus saimiri has been developed. Virus titrations carried out in Microtest II tissue culture plates (Falcon) yielded reproducible results that agreed well with those obtained by employing macrocultures. The described method is quantitative, reproducible, economical, and suitable for routine assay of large numbers of virus samples. PMID- 4201643 TI - Sensitivity of three selected bacterial species to ozone. AB - THE MINIMAL LETHAL CONCENTRATION OF OZONE IN WATER WAS DETERMINED FOR THREE BACTERIAL SPECIES: Escherichia coli, Bacillus cereus, and Bacillus megaterium. A contact period of 5 min was selected. The lethal threshold concentration for the cells of B. cereus was 0.12 mg/liter while that for E. coli and B. megaterium was 0.19 mg/liter. Low concentrations of ozone were ineffective when organic matter was present to interfere with the action of ozone on the bacterial cells. Also determined during the study was the sensitivity of spores of B. cereus and B. megaterium to ozone in water. The threshold concentration required to kill the spores of both species was 2.29 mg/liter. The cells and spores of these organisms exhibited the "all-or-none" die-away phenomenon normally associated with ozone treatment. PMID- 4201644 TI - Lytic activity of vibrio phages on strains of Vibrio fetus isolated from man and animals. AB - Five phages isolated from lysogenic strains of Vibrio fetus var. venerealis and two from V. fetus var. intestinalis were tested for lytic activity on 95 V. fetus strains from various animal and human hosts. In addition, virion and plaque morphology of the seven phages were compared. Electron micrographs showed that all were the kite-tailed variety with minor variations in head and tail dimensions. Plaques of V45 and V2 were small, clear and irregular; those of V3, V8, and V19 were large, clear and regular at the edge; the plaques of V16 and V20 were intermediate in size, clear, and very irregular at the edge with satellite plaques. The number of strains lysed by one or more phages were as follows: 29 of 30 from cattle; 7 of 11 from sheep; 1 of 5 from pigs; 1 of 1 from a monkey; and 33 of 42 from human hosts. Four natural groups of phages were derived by statistical measures of percentage of similarity in lytic activity. Group III lysed more strains (46 of 95) than any of the others. Twenty-five strains were lysed by group IV, 23 strains by group I, and 19 strains by group II. Results of this study indicate that phage typing should be a practical supplement to other differential tests for V. fetus. PMID- 4201645 TI - Modification of the starch block electrophoresis method for the preparation of immunoglobulin A from multiple myeloma sera on a large scale. AB - Separation of immunoglobulin A from a large sample of human serum from patients with multiple myeloma was done by utilizing a large zone electrophoresis apparatus. PMID- 4201646 TI - Clinical evaluation of sodium amylosulfate in human blood cultures. AB - Sodium amylosulfate was shown to be a useful anticoagulant additive for increased isolation of bacteria from clinical blood cultures. PMID- 4201647 TI - Temperature adaptability of psychrotrophic Pseudomonas. AB - The rate of oxidation of glucose and alanine at low temperatures by washed cells of psychrotrophic strains of Pseudomonas is related to growth temperature. PMID- 4201648 TI - Comparison of atmospheric conditions for culture of clinical specimens of Neisseria gonorrhoeae. AB - We cultured 55 clinical specimens of Neisseria gonorrhoeae in the following atmospheric conditions: (i) 10% carbon dioxide in a CO(2) incubator; (ii) a candle extinction jar; (iii) an air convection incubator; and (iv) an anaerobic jar without added CO(2). The number and size of colonies growing on modified Thayer-Martin medium were evaluated after incubation of cultures for 24 and 48 h at 36 C. After 24 h, the specimens from the candle extinction jar had the greatest number and size of colonies, but after 48 h growth was approximately equal for specimens from the candle jar and the CO(2) incubator. Only 19 of 55 specimens grew in the air convention incubator. None of 55 clinical specimens or of 10 laboratory strains grew anaerobically. Development of colonial morphology for colony types 1, 2, 3, and 4 was studied at 24 h on a base medium that contained no hemoglobin. The relative numbers of the four colony types in specimens were comparable after 24 h of incubation in any of the three atmospheric conditions under which growth occurred, but the different types were distinguished most readily when grown in the candle extinction jar. PMID- 4201649 TI - Microtiter solid-phase radioimmunoassay for hepatitis B antigen. AB - A micro-solid-phase radioimmunoassay (micro-SPRIA) for hepatitis B antigen (HB Ag) was developed for use with microtiter serological equipment. Radiolabeled immunoglobulin G was prepared from human and animal sera containing hepatitis B antibody (HB Ab); it was not necessary to isolate specific HB Ab by immunochemical means. A micro-SPRIA prepared with guinea pig reagents was approximately as sensitive as the AusRIA radioimmunoassay, but, like the AusRIA test, yielded false positive results. A micro-SPRIA prepared with human reagents was slightly less sensitive but did not yield false positive results. These micro SPRIA tests offer several advantages, including conservation of reagents, adaptability to other antigen-antibody systems, ease of performance (especially when testing large numbers of specimens), and economy. PMID- 4201650 TI - Effect of glutaraldehyde on cell viability, triphenyltetrazolium reduction, oxygen uptake, and beta-galactosidase activity in Escherichia coli. AB - Acid (pH 5) and alkaline (pH 8.5) glutaraldehyde solutions were compared for their effects on cell viability, oxygen uptake, and beta-galactosidase activities in Escherichia coli. The action of glutaraldehyde at pH 7 on dehydrogenase activity was also studied. Dehydrogenase activity was inhibited at aldehyde concentrations which had little effect on cell viability. In contrast, oxygen uptake and beta-galactosidase activity took place in cells killed by acid or alkaline glutaraldehyde. The effect of glutaraldehyde on dehydrogenase activity and beta-galactosidase activity of disrupted suspensions was also investigated. The dialdehyde was considerably less inhibitory to these enzyme systems than to those of whole cells, and it is thus feasible that the results with whole cells are a consequence of its interaction with, and strengthening of, the outer cell surface, thereby preventing ready access of substrate to enzyme. PMID- 4201651 TI - [Propagation of excitation along a fiber with local non-uniformities (results of modelling)]. PMID- 4201652 TI - Peroxidase diffusion in the normal sensory retina. PMID- 4201653 TI - Treatment of central nervous system leukemia with intrathecal cytosine arabinoside. PMID- 4201654 TI - Controlled prospective trial of Pseudomonas aeruginosa vaccine in children with acute leukemia. PMID- 4201655 TI - Yolk sac tumor (endodermal sinus tumor) and alpha-fetoprotein. A report of three cases. PMID- 4201656 TI - The effect of clinical pharmacy services on patients with essential hypertension. PMID- 4201657 TI - Congenital diverticulum of the left ventricle associated with hypoplastic right ventricle and ventricular septal defect. PMID- 4201658 TI - Editorial: Nitrates in the prophylactic treatment of angina pectoris. PMID- 4201659 TI - Influence of albumin on the hepatic uptake of unconjugated bilirubin. PMID- 4201660 TI - Relationship between plasma cortisol and peak expiratory flow rat in exercise induced asthma and the effect of sodium cromoglycate. PMID- 4201661 TI - Suppression of plasma renin by atherogenic levels of serum cholesterol in rabbits. PMID- 4201662 TI - Induction of glycoprotein mating factors in diploid yeast of Hansenula wingei by vanadium salts or chelating agents. PMID- 4201663 TI - Non-histone proteins. The effect of nuclear washes and comparison of metaphase and interphase chromatin. PMID- 4201664 TI - Binding of a tritiated thyrotropin-releasing factor to a prolactin secreting clonal cell line (GH3). PMID- 4201665 TI - Transition-state analogs of an aliphatic amidase. PMID- 4201666 TI - Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus. PMID- 4201667 TI - Inhibition of leucocyte migration by tumour-associated antigens of the colon and rectum. AB - The test of leucocyte migration inhibition has been used to detect lymphocyte sensitization to tumour-associated antigens of the colon and rectum. The procedure for the isolation of antigens from colorectal adenocarcinomata and normal colonic mucosa is described. The circulating lymphocytes of 22 patients suffering from colorectal adenocarcinomata of various stages have been examined and compared with the results obtained for identical studies performed on the peripheral lymphocytes of 15 control subjects. Sensitization of lymphocytes to tumour antigen was demonstrated in 15 of the 22 patients when culture was performed in homologous AB serum. Of these 15 patients only six showed inhibition of leucocyte migration in the presence of tumour extract when culture was performed in autologous serum. These observations would suggest the presence of factors in the serum of such patients which may prevent the expression of cellular immunity to tumour antigens. PMID- 4201668 TI - Gluconeogenesis from amino acids in mature wether sheep. PMID- 4201669 TI - Studies of the protein requirement of the neonatal rat. PMID- 4201670 TI - Differential effects of protein-calorie restriction and subsequent repletion on neuronal and nonneuronal components of cerebral cortex in newborn rats. PMID- 4201671 TI - Letter: Selenium and dental caries susceptibility. PMID- 4201672 TI - Conformation of sodium cromolyn in aqueous solution using light scattering and magnetic birefringence. PMID- 4201673 TI - Partial purification of antigen E from mixed stems and leaves of short ragweed plant. PMID- 4201674 TI - Assay of thiotepa by PMR spectrometry. PMID- 4201675 TI - [Cerebral gigantism. Clinical and biological study of 5 cases]. PMID- 4201676 TI - [Determination of bacterial resistance in the clinical laboratory]. PMID- 4201678 TI - Concentration of penicillin V and tetracycline in maxillary sinus secretion after repeated doses. PMID- 4201677 TI - [Study on the efficacy of a new antiepileptic drug (Rivotril) in various forms of epilepsy]. PMID- 4201679 TI - Shift in viral strains of hepatitis B in Stockholm as reflected by subtypes of hepatitis B antigen. PMID- 4201680 TI - Hepatitis-associated antigen, subtypes D and Y. An epidemiological and clinical evaluation. PMID- 4201681 TI - Experimental alcoholic hepatitis: a new primate model. AB - Research into the pathogenesis of alcoholic cirrhosis has suffered from the lack of an animal model of alcoholic hepatitis, considered by many to be the link between alcoholic fatty liver and cirrhosis. The entire constellation of histologic features characteristic of alcoholic hepatitis has been produced for the first time in baboons by administration of ethanol with a nutritionally adequate diet. This includes fat, necrosis. inflammation, alcoholic hyaline, fibrosis, and central hyaline sclerosis. PMID- 4201682 TI - Phosphate-induced protein chromatography. AB - High phosphate concentration is shown to cause a large proportion of the proteins of a cell-free extract of Escherichia coli to bind to agarose columns to which L valine is attached. With a decreasing concentration gradient of potassium phosphate, the proteins elute in relation to their solubility in concentrated ammonium sulfate. This column technique appears to provide a general tool for the purification of proteins. PMID- 4201683 TI - Unstable angina. PMID- 4201684 TI - Readiness for synthesis of red and brown pigments in the imaginal eye disks of Drosophila melanogaster. PMID- 4201685 TI - The pattern of epilepsy in Uganda. PMID- 4201686 TI - Pathogenic leptospira isolated from toad kidneys. PMID- 4201688 TI - [Disodium cromoglycate: preliminary report of its clinical trial in Cuba]. PMID- 4201689 TI - Comparative aspects of morphogenesis in three prokaryotic genera. PMID- 4201690 TI - Nitrogen fixation by photosynthetic microorganisms. PMID- 4201691 TI - Biology of Trypanosoma cruzi. PMID- 4201692 TI - Characterization of circadian oscillations in alanine dehydrogenase activity in non-dividing populations of Euglena gracilis (Z). PMID- 4201693 TI - Studies on the biochemical basis of oxygen toxicity. PMID- 4201696 TI - Psychotrophic gram-positive bacteria: temperature effects on growth and solute uptake. PMID- 4201695 TI - Specificity of cell wall labeling with triated diaminopimelic acid in Bacillus subtilis. PMID- 4201694 TI - Antigenic variants of influenza B virus. AB - From 1967 to 1971 little antigenic variation was detected in the prevalent influenza B viruses but in December 1972 a new antigenic variant of influenza B was isolated in Hong Kong from sporadic cases of influenza. The new variant, B/Hong Kong/5/72, possessed a haemagglutinin antigen which showed considerable antigenic differences from that of former influenza B strains while its neuraminidase antigen was closely related to that of the earlier, 1967-71, isolates. The B/Hong Kong/5/72 variant became the predominant influenza B strain in the United Kingdom by early summer 1973, and in both the United Kingdom and Japan this strain was associated with outbreaks of influenza. Strains antigenically intermediate between the 1967-71 isolates and B/Hong Kong/5/72 were isolated in a number of countries, often concurrently with B/Hong Kong/5/72-like strains.Serological studies indicated that antibody to B/Hong Kong/5/72 was infrequent in the populations in the United Kingdom and the U.S.A., suggesting the possibility of future epidemic activity associated with the new variant. In addition, conventional inactivated influenza vaccines containing the older influenza B isolates given to volunteers stimulated poor antibody responses to B/Hong Kong/5/72 virus. These studies indicate the desirability of immunizing high risk patients against B/Hong Kong/5/72-like viruses before the coming influenza season. Vaccine containing the new variant influenza B strain are currently available in the United Kingdom. PMID- 4201697 TI - Antigenic comparison between in vivo and in vitro grown tubercle bacilli. PMID- 4201699 TI - The phyloantigenic position of nocardiae revealed by examination of cytoplasmic antigens. PMID- 4201698 TI - Control of tartrate utilization in Aspergillus flavus. PMID- 4201700 TI - Favorable effects in vitro and in vivo of two clinical isolates of Pseudomonas aeruginosa on nutritionally deficient Staphylococcus aureus strains. PMID- 4201701 TI - [Continuous low flow enteral resuscitation]. PMID- 4201702 TI - Supplementary parenteral nutrition in patients with malignant disease. Guidelines to patient selection. PMID- 4201703 TI - Distribution along X-chromosome of recessive lethals induced by direct and indirect X-radiation effect in Drosophila. PMID- 4201704 TI - Effect of phenobarbital and DL-ethionine on 4-(dimethylamino)azobenzene metabolizing enzymes and carcinogenesis. PMID- 4201705 TI - Australia (hepatitis-associated) antigen in urban endemic hepatitis at Poona. PMID- 4201707 TI - Analysis of the schedule of DNA replication in heat-synchronized Tetrahymena. AB - The temporal schedule of DNA replication in heat-synchronized Tetrahymena was studied by autoradiographic and cytofluorometric methods. It was shown that some cells, which were synchronized by selection of individual dividing cells or by temporary thymidine starvation, incorporated [(3)H]thymidine into macronuclei in a periodic fashion during the heat-shock treatment. It was concluded that supernumerary S periods occurred while cell division was blocked by high temperature. The proportion of cells which initiated supernumerary S periods was found to be dependent on the duration of the heat-shock treatment and on the cell cycle stage when the first heat shock was applied. Cytofluorometric measurements of Feulgen-stained macronuclei during the heat-shock treatment indicated that the DNA complement of these cells was substantially increased and probably duplicated during the course of each S period. Estimates of DNA content also suggested that the rate of DNA synthesis progressively declined during long heat-shock treatments. These results indicate that the mechanism which brings about heat induced division synchrony is not an interruption of the process of DNA replication. Further experiments were concerned with the regulation of DNA synthesis during the first synchronized division cycle. It was shown that participation in DNA synthesis at this time increased as more cells were able to conclude the terminal S period during the preceding heat-shock treatment. It is suggested that a discrete period of time is necessary after the completion of DNA synthesis before another round of DNA synthesis can be initiated. PMID- 4201706 TI - The relationship of concanavalin A binding to lectin-initiated cell agglutination. AB - We have investigated the relationship of concanavalin. A binding to the cell surface of normal and transformed cells and the subsequent agglutination of the transformed cells. At room temperature almost no differences could be detected in agglutinin binding between transformed and untransformed cells. At 0 degrees C, however, where endocytosis was negligible, the transformed cells bound three times more agglutinin. However, transformed cells and trypsin-treated normal cells do not agglutinate at 0 degrees C although the amounts of agglutinin bound at 0 degrees C are sufficient to permit agglutination when such cells are shifted up to room temperature. Both transformed and trypsin-treated normal cells show a marked increase in agglutination at 15 degrees C as compared to agglutination at 0 degrees C. From this, as well as the observation that mild glutaraldehyde fixation of the cell surface inhibited agglutination but not agglutinin binding, it was concluded that concanavalin A-mediated cell agglutination requires free movement of the agglutinin receptor sites within the plane of the cell surface. PMID- 4201708 TI - Localization of polysome-bound albumin and serine dehydratase in rat liver cell fractions. AB - The polysomes involved in albumin and serine dehydratase synthesis were identified and localized by the binding to rat liver polysomes of anti-rat serum albumin and anti-serine dehydratase [(125)I]Fab dimer and monomer. Techniques were developed for the isolation of undegraded free and membrane-bound polysomes and for the preparation of [(125)I]Fab monomers and dimers from the IgG obtained from the antisera to the two proteins, rat serum albumin and serine dehydratase. The distribution of anti-rat serum albumin [(125)I]Fab dimer in the polysome profile is in accordance with the size of polysomes that are expected to be synthesizing albumin. By direct precipitation, it has been demonstrated that nascent chains isolated from the membrane-bound polysomes by puromycin were precipitated by anti-rat serum albumin-IgG at a level of 5-6 times those released from free polysomes. Anti-rat serum albumin-[(125)I]Fab dimer reacted with membrane-bound polysomes almost exclusively compared to the binding of nonimmune, control [(125)I]Fab dimer; a significant degree of binding of anti-rat serum albumin-[(125)I]Fab to free polysomes was also obtained. The [(125)I]Fab dimer made from normal control rabbit serum does not react with polysomes from liver at all and this preparation will not interact with polysomes extracted from tissues that do not synthesize rat serum albumin. Both anti-serine dehydratase [(125)I]Fab monomer and dimer react with free and bound polysomes from livers of animals fed a chow diet or those fed a high 90% protein diet and given glucagon. In the latter instance, however, it is clear that the majority of the binding occurs to the bound polysomes. Furthermore, the specificity of this reaction may be further shown by the use of kidney polysomes that do not normally synthesize serine dehydratase. When these latter polysomes are isolated, even after the addition of crude and purified serine dehydratase, no reaction with anti-serine dehydratase-Fab fragments could be demonstrated. These results indicate that the reaction of the Fab fragments are specific for polysomes that synthesize rat serum albumin or rat liver serine dehydratase. Furthermore, they demonstrate that even with this high degree of specificity, some polysomes in the fraction labeled "free" are in the process of synthesizing rat serum albumin while bound polysomes to a significant, if not major, degree are the site of the synthesis of rat liver serine dehydratase. PMID- 4201709 TI - Effect of aldosterone on active and passive conductance and ENA in the toad bladder. PMID- 4201710 TI - [Mechanism of neurohypophyseal hormone secretion. Cellular and subcellular aspects]. PMID- 4201711 TI - [Gastrointestinal involvement in neurofibromatosis (Recklinghausen's disease) (author's transl)]. PMID- 4201712 TI - Nitrobenzene reduction and reductive cleavage of azobenzenes in two species of Arachnida. PMID- 4201713 TI - An electron cytochemical study of 6-phosphogluconate dehydrogenase activity in infected erythrocytes during malaria. PMID- 4201714 TI - [Problems of resuscitation posed by postasphyxic syndromes with inhalation. Apropos of 2OO cases]. PMID- 4201715 TI - Analysis of lipoxygenase nonvolatile reaction products of linoleic acid in aqueous cereal suspensions by urea extraction and gas chromatography. PMID- 4201716 TI - Enzymatic oxidation of linolenic acid in aqueous wheat flour suspensions. PMID- 4201717 TI - [Pharyngomycosis leptothrichina as pseudomycosis close to opportunistic mycoses]. PMID- 4201718 TI - Symposium on the patient with long-term illness. Foreword. PMID- 4201719 TI - Social isolation and the nursing process. PMID- 4201720 TI - Juvenile diabetes mellitus. PMID- 4201721 TI - Long-term care of the patient with cancer. PMID- 4201722 TI - Human sexuality and nursing practice. PMID- 4201723 TI - [Detection of hepatitis associated antigen in donors]. PMID- 4201724 TI - [Morphological changes in the pulmonary vessels in postvaccinal and infectious allergy in an experiment]. PMID- 4201725 TI - [Nosology, genetics and therapy of endogenous psychotic syndromes from the viewpoint of unitary psychoses (universal etiology of psychoses)]. PMID- 4201726 TI - [Nosology in the area of endogenous psychoses]. PMID- 4201727 TI - [An attempt at statistical studies on multiple factor etiology in endogenous psychoses]. PMID- 4201728 TI - [Nosology of psychoses. Multiple factor synoptical comprehension with syndrome genetic approach]. PMID- 4201729 TI - [The interlocking of psychosociogenic, somatogenic and endogenous factors in the psychoses of involutional age]. PMID- 4201730 TI - [Statistical report on examination results of 604 psychotics]. PMID- 4201731 TI - [Typology of schizophrenia from prognostic-therapeutic aspects]. PMID- 4201732 TI - [Significance of type and localization of electroencephalographic focal findings in children with epilepsy]. PMID- 4201733 TI - [Multiple duodenal diverticulosis. Apropos of 6 cases]. PMID- 4201735 TI - Pulpal responses to "composite" dental materials lined with Tubulitec or Dropsin. PMID- 4201734 TI - [Hypothalamic control of thyroid function]. PMID- 4201736 TI - A histopathologic study of replanted teeth with superficially demineralized root surfaces in Java monkeys. PMID- 4201737 TI - The immunoglobulin concentrations in serum and bowel secretion in patients with Crohn's disease. PMID- 4201738 TI - Jejunal disaccharidases in children with selective IgA deficiency. PMID- 4201739 TI - [Metachromatic leukodystrophy--a neurolipidosis]. PMID- 4201741 TI - [Preparations containing hexachlorophene. Directions for use]. PMID- 4201740 TI - [Disodium cromoglycate and exercise induced airway obstruction]. PMID- 4201742 TI - Prevention of Rh-immunization. Modified production of IgG anti-Rh for intravenous application by ion exchange chromatography (IEC). PMID- 4201743 TI - Production of antibodies against hepatitis-associated antigen in donkeys. PMID- 4201744 TI - [Column-chromatographic enrichment of DNA-polymerase activity in leukemia]. PMID- 4201745 TI - [Richter's syndrome. 4 cases and an attempt at analysis]. PMID- 4201746 TI - [Effect of cyclophosphamide on megakaryocyte enzymes]. PMID- 4201747 TI - Some aspects of leucocyte behaviour in haemodialysis. PMID- 4201748 TI - Congenital hypoproconvertinemia (factor VII deficiency). A report of two cases belonging to two different kindreds. PMID- 4201749 TI - Platelet defect in a case of Ehlers-Danlos syndrome. PMID- 4201750 TI - Pyknocytosis in heat-stroke. PMID- 4201752 TI - Mixed sodium chloride aerosol and nitrogen dioxide in air: biological effects on monkeys and rats. PMID- 4201751 TI - Beta-adrenergic blockade in essential hypertension. Effects of propranolol on hemodynamic parameters and plasma renin activity. PMID- 4201753 TI - Lymphocytic beta-glucuronidase in the lymphoproliferative syndromes. PMID- 4201754 TI - The availability of food folate in man. PMID- 4201755 TI - Some applications of quantitative whole-body scanning in haematology. PMID- 4201756 TI - Carcinoma of the duodenum: comparison of surgery, radiotherapy, and chemotherapy. PMID- 4201757 TI - Proceedings: factors determining marker concentration during continuous blood volume measurement during haemorrhage and infusion. PMID- 4201758 TI - Proceedings: the role of humoral factors and diamine oxidase activity in shock after intestinal ischaemia in rabbits. PMID- 4201759 TI - Proceedings: implantation of pancreatic islets into the portal vein of diabetic rats. PMID- 4201760 TI - Proceedings: the survival of transplanted isolated pancreatic islets in the omentum and testis. PMID- 4201761 TI - Proceedings: human and computer-aided diagnosis of lower gastro-intestinal disorders in 468 patients. PMID- 4201762 TI - The origin, course and termination of vestibulospinal fibers in the toad. An experimental-anatomical study, with comments on other descending supraspinal fiber systems to the spinal cord. PMID- 4201763 TI - Effects of artificial mothers and visual experience on adrenal responsiveness of infant monkeys. PMID- 4201764 TI - Testosterone-binding globulin in stump-tailed macaque monkeys (Macaca speciosa). PMID- 4201765 TI - Acute and chronic oral toxicity of chlorinated dibenzofurans to salmonid fishes. PMID- 4201766 TI - The search for chlorinated dibenzofurans and chlorinated dibenzodioxins in wildlife populations showing elevated levels of embryonic death. PMID- 4201767 TI - Biological responses of the nonhuman primate, chicken, and rat to chlorinated dibenzo-p-dioxin ingestion. PMID- 4201769 TI - Electron microscopic localization of occluding junctions in the primate ciliary process and pars plana. PMID- 4201768 TI - Etiology of chick edema disease. PMID- 4201770 TI - Changes in corticosteroid usage by chronic asthma patients during a year of cromoglycate treatment. PMID- 4201772 TI - Immersion refractometry of isolated bacterial cell walls. AB - Immersion-refractometric and light-scattering measurements were adapted to determinations of average refractive indices and physical compactness of isolated bacterial cell walls. The structures were immersed in solutions containing various concentrations of polymer molecules that cannot penetrate into wall pores, and then an estimate was made of the polymer concentration or the refractive index of the polymer solution in which light scattering was reduced to zero. Because each wall preparation was heterogeneous, the refractive index of the medium for zero light scattering had to be estimated by extrapolation. Refractive indices for walls suspended in bovine serum albumin solutions ranged from 1.348 for walls of the rod form of Arthrobacter crystallopoietes to 1.382 for walls of the teichoic acid deficient, 52A5 strain of Staphylococcus aureus. These indices were used to calculate approximate values for solids content per milliliter, and the calculated values agreed closely with those estimated from a knowledge of dextran-impermeable volumes per gram, dry weight, of the walls. When large molecules such as dextrans or serum albumin were used for immersion refractometry, the refractive indices obtained were for entire walls, including both wall polymers and wall water. When smaller molecules that can penetrate wall pores to various extents were used with Micrococcus lysodeikticus walls, the average, apparent refractive index of the structures increased as the molecular size of probing molecules was decreased. It was possible to obtain an estimate of 1.45 to 1.46 for the refractive index of wall polymers, predominantly peptidoglycans in this case, by extrapolating the curve for refractive index versus molecular radius to a value of 0.2 nm, the approximate radius of a water molecule. This relatively low value for polymer refractive index was interpreted as evidence in favor of the amorphous, elastic model of peptidoglycan structure and against the crystalline, rigid model. PMID- 4201771 TI - Role of methionine in biosynthesis of prodigiosin by Serratia marcescens. AB - Methionine alone did not allow biosynthesis of prodigiosin (2-methyl-3-amyl-6 methoxyprodigiosene) in nonproliferating cells (NPC) of Serratia marcescens strain Nima. However, when methionine was added to NPC synthesizing prodigiosin in the presence of other amino acids, the lag period for synthesis of prodigiosin was shortened, an increased amount of the pigment was formed, and the optimal concentrations of the other amino acids were reduced. Less prodigiosin was synthesized when addition of methionine was delayed beyond 4 h. The specific activity of prodigiosin synthesized by addition of (14)CH(3)-methionine was 40 to 50 times greater than that synthesized from methionine-2-(14)C or (14)COOH methionine. NPC of mutant OF of S. marcescens synthesized norprodigiosin (2 methyl-3-amyl-6-hydroxyprodigiosene), and the specific activity of this pigment synthesized in the presence of (14)CH(3)-methionine was only 5 to 13 times greater than that synthesized from methionine-2-(14)C or (14)COOH-methionine. A particulate, cell-free extract of mutant WF of S. marcescens methylated norprodigiosin to form prodigiosin. When the extract was added to NPC of mutant OF synthesizing norprodigiosin in the presence of (14)CH(3)-methionine, the prodigiosin formed had 80% greater specific activity than the norprodigiosin synthesized in the absence of the extract. The C6 hydroxyl group of norprodigiosin was methylated in the presence of the extract and methionine. Biosynthesis of prodigiosin by NPC of strain Nima also was augmented by addition of S-adenosylmethionine. Various analogues of methionine such as norleucine, norvaline, ethionine, and alpha-methylmethionine did not affect biosynthesis of prodigiosin by NPC either in the presence or absence of methionine. PMID- 4201773 TI - Sites of cellular autolysis in Lactobacillus acidophilus. AB - Ultrastructural changes which occur during cellular autolysis of Lactobacillus acidophilus strain 63AM Gasser in 0.05 M citrate buffer, pH 5.0, were examined. Early in the process, randomly distributed electron-dense patches were seen on the wall surface, along with an accompanying eversion of mesosomes. Later, after a loss of about 20% of the initial cellular turbidity, dissolution from the outside of nascent cross walls was seen. This observation was related to the normal process of cell separation. After this stage, short lengths of the cylindrical portion of the wall appeared to be completely removed in a random manner over the entire surface. This dissolution produced gaps in the wall which allowed the extrusion of membrane and cytoplasm. Although membrane was usually extruded through one major, polar, subpolar, or septal site, other secondary points of membrane extrusion were also frequently seen in the same cell section. PMID- 4201774 TI - Isolation of the bacteriophage lambda receptor from Escherichia coli. AB - A factor which inactivates the phage lambda can be extracted from Escherichia coli. This factor is a protein and is located in the outer membrane of the bacterial envelope. It is found in extracts of strains which are sensitive to phage lambda, but not in extracts of strains specifically resistant to this phage. We conclude that this factor is the lambda receptor, responsible for the specific adsorption of the phage lambda to E. coli cells. A partial purification of the lambda receptor is described. Inactivation of the phage by purified receptor is shown to be accompanied by the release of deoxyribonucleic acid from the phage. PMID- 4201777 TI - Kinetic studies of citrate synthase from rat kidney and rat brain. PMID- 4201775 TI - New procedure for the isolation of membrane vesicles of Bacillus subtilis and an electron microscopy study of their ultrastructure. AB - A rapid procedure for the isolation of membrane vesicles of Bacillus subtilis is described that minimizes the action of proteolytic enzymes, excreted by this organism, on the membrane proteins. The membrane vesicles obtained have, in addition to a low endogenous respiration rate, a low endogenous activity for transport of amino acids and carboxylic acids. In the presence of the electron donor, ascorbate-phenazine methosulfate, the transport activities for these compounds were comparable to the activities of intact cells. In addition, these activities were retained for a prolonged period of time. Electron microscopy examination of thin sections of the vesicles showed that the preparation consisted almost exclusively of membrane vesicles which were not contaminated with other cell components. The membrane vesicles, which are six to seven times smaller in diameter than protoplasts, often enclosed smaller vesicles. Freeze etching of intact cells, protoplasts, and membrane vesicles showed that the orientation of the membrane of the vesicles was identical to the orientation of the plasma membrane in intact cells and protoplasts. This also held for the majority of the membranes of the enclosed vesicles, only 15% having the opposite orientation. PMID- 4201776 TI - Developmental block in citric acid cycle mutants of Bacillus subtilis. AB - Mutants deficient in different enzymes of the citric acid cycle can be subdivided into two groups according to the frequency at which they produce heat-resistant spores in nutrient sporulation medium. However, the majority of cells can develop in this medium only to the axial filament stage I of sporulation; aconitase and isocitrate dehydrogenase mutants need the addition of glutamate to reach this stage. PMID- 4201779 TI - Structural organization of three pools of acetyl coenzyme A in Tetrahymena. PMID- 4201778 TI - Multiple genes for lysozyme in birds. Studies on black swan egg white lysozymes. PMID- 4201780 TI - Effect of tolbutamide on the intracellular flow of acetyl coenzyme A in Tetrahymena. PMID- 4201781 TI - Effect of adenosine monophosphate on intermediate metabolism and ribonucleic acid synthesis in Tetrahymena. PMID- 4201782 TI - Studies on a nuclease from Ustilago maydis. I. Purification, properties, and implication in recombination of the enzyme. PMID- 4201783 TI - Ionization behavior of the histidine residue in the catalytic triad of serine proteases. Mechanistic implications. PMID- 4201785 TI - Serum heat stable alkaline phosphatase levels in normal and abnormal pregnancies. PMID- 4201784 TI - Response of rats to amino acid supplementation of brown egg albumin. PMID- 4201786 TI - Amino acid utilization during total parenteral nutrition in the surgical neonate. PMID- 4201787 TI - The long-term total intravenous feeding of infants using peripheral veins. PMID- 4201788 TI - Structural organization of the pars plana-ora serrata transition in the human and monkey eye with emphasis on protein barriers. PMID- 4201789 TI - Circulating tissue antigens. II. Studies on an organ-specific antigen of human liver. PMID- 4201791 TI - Letter: Neurotoxic effects of glutamate. PMID- 4201790 TI - Solubilized myocardial adenylate cyclase: activation by prostaglandins. PMID- 4201792 TI - Letter: Stimulant drugs for problem children. PMID- 4201793 TI - Neurofibromatosis, renal artery aneurysms and hypertension: case report. PMID- 4201794 TI - Anterior urethral valves. PMID- 4201795 TI - Streptococcal epidemic in an aircraft carrier. PMID- 4201796 TI - Determination of trace quantities of anticholinesterase pesticides. PMID- 4201797 TI - Carbonic anhydrase: a new method of detection on polyacrylamide gels using conductivity measurements. PMID- 4201798 TI - [Present bacteriology of chronic otitis. Antibiotic diffusion in the tissues of the middle ear: Therapeutic consequences]. PMID- 4201799 TI - [Problems of acute ventricular aneurysms and dyskinesias. Indications for early ventricular resection. (Apropos or 14 operative cases)]. PMID- 4201800 TI - [Infarctectomy and left ventricular aneurysmectomy. Apropos of 16 cases]. PMID- 4201801 TI - [Treatment of auricular flutter using endocavitary auricular stimulation]. PMID- 4201802 TI - [Phonomechanography of chronic coronary insufficiency. Mechanograms. The phonomechanographic profile]. PMID- 4201803 TI - [Angiocardiographic diagnosis of the double-outlet right ventricle. Apropos of 15 cases]. PMID- 4201804 TI - [Hemodynamic study of 18 cases of double-outlet right ventricle (correlation with angiocardiography)]. PMID- 4201805 TI - [Auscultation and phonomechanography of bundle-branch block]. PMID- 4201806 TI - [Jean Nouaille, 1909-1972]. PMID- 4201807 TI - Lipid-protein interactions of erythrocyte membranes: comparison of normal O, Rh (D) positive with the rare O, Rh null. PMID- 4201808 TI - Mucopolysaccharidosis 3 A (Sanfilippo A disease): deficiency of a heparin sulfamidase in skin fibroblasts and leucocytes. PMID- 4201809 TI - Study on the existence of TRH in the cerebrospinal fluid in humans. PMID- 4201810 TI - Gel electrophoresis of partially purified cytochromes P450 from liver microsomes of variously-treated rats. PMID- 4201812 TI - A tanned cell haemagglutination test for the detection of hepatitis-associated antigen (Au-Ag) and antibody (anti-Au). PMID- 4201811 TI - Comparison of techniques for quantifying serum alpha1-antitrypsin. PMID- 4201813 TI - Voltammetric identification of organochlorine insecticides, polychlorinated biphenyls, polychlorinated naphthalenes and polychlorinated benzenes. PMID- 4201814 TI - Experiments on Rouleu formation. PMID- 4201815 TI - Dose-related effects of isoprenaline on the distribution of cardiac output and myocardial blood flow in conscious monkeys. PMID- 4201816 TI - Experience with the use of computer simulation models in medical education. PMID- 4201818 TI - Immunochemical analysis of tissue antigens in different corneal layers and sclera. PMID- 4201817 TI - The treatment of asthma. PMID- 4201820 TI - Competition between inoculum strains of Rhizobium japonicum in the process of soybean nodulation during three planting periods. PMID- 4201819 TI - Effect of different complex nutrients on neomycin production by Streptomyces fradiae H. PMID- 4201821 TI - Distribution of ABO and rhesus blood groups in patients with gastric carcinoma, with reference to its site of origin. PMID- 4201822 TI - Tuberculous enteritis. A report of three patients. PMID- 4201823 TI - [Diagnosis and therapy of advanced bladder carcinoma]. PMID- 4201824 TI - Transmission of IgA to the rabbit foetus and the suckling rat. PMID- 4201827 TI - Studies on the mode of action of glutaraldehyde on Escherichia coli. PMID- 4201828 TI - Germination of spores of Bacillus cereus in milk and milk dialysates: effect of heat treatment. PMID- 4201825 TI - Cross-reactive human blood group H-active polysaccharide from Helix pomatia. I. Detection with catfish anti-H and eel sera. PMID- 4201826 TI - Border disease-like syndrome in lambs: antibodies to hog cholera and bovine viral diarrhea viruses. PMID- 4201829 TI - A quantitative comparison of the faecal microflora of baboons fed a natural diet or a synthetic diet complete or deficient in pyridoxine or riboflavin. PMID- 4201830 TI - Increased serum thyroxine levels in euthyroid narcotic addicts. PMID- 4201832 TI - A simple precipitin test for corticosteroid-binding globulin: use in a search for the absence of corticosteroid-binding globulin in 10,000 subjects. PMID- 4201831 TI - Abnormalities of hypothalamo-hypophyseal-thyroid axis in patients with Graves' ophthalmopathy. PMID- 4201833 TI - Ferritin-tagged antibody cross-reactions among rinderpest, canine distemper, and measles viruses. PMID- 4201834 TI - The production of interferon by chemostat cultures of mouse LS-cells grown in chemically-defined, protein-free medium. PMID- 4201835 TI - Characterization of three phages lytic for Brucella species. PMID- 4201836 TI - The growth of two togaviruses in cultured mosquito and vertebrate cells. PMID- 4201837 TI - The length of the filamentous Pseudomonas aeruginosa bacteriophage Pf. PMID- 4201838 TI - [Characterization of two temperature-sensitive mutants of Sigma virus (authors transl)]. PMID- 4201839 TI - The significance of plasma proteins in urinary casts. PMID- 4201840 TI - The effects of agents that modify muscarinic tone upon behavior controlled by an avoidance schedule that employs signaled unavoidable shock. PMID- 4201841 TI - [Development of resistance to Mycobacterium tuberculosis in Chile]. PMID- 4201842 TI - [A case of anti-Dia found in a Mexican woman]. PMID- 4201843 TI - [Corticoid-induced psychovegetative disorders and their therapy using Sinquan]. PMID- 4201844 TI - Standardized horse antihuman lymphocyte globulin for clinical use. PMID- 4201846 TI - [Acute fatal incident following anticoagulant therapy]. PMID- 4201845 TI - [Experimental studies of the effect of temporary hyperthermia on bladder tumors (author's transl)]. PMID- 4201847 TI - [Double-blind study of the sulfamethoxazole-trimethoprim association in the treatment of pulmonary infections]. PMID- 4201848 TI - Mechanisms of motor control of two types of tracking movements in monkeys. PMID- 4201850 TI - [Erythrocyte osmotic resistance during various forms of stress]. PMID- 4201849 TI - [Study of the bactericidal activity of an iodinated polyvinylpyrrolidone]. PMID- 4201851 TI - Electron microscope study of the endothelium of stored and cryopreserved monkey corneas. PMID- 4201852 TI - Pseudomonas aeruginosa endocarditis. Report of a case, with review of the literature. PMID- 4201853 TI - [Intramolecular participation of aromatic amino groups (author's transl)]. PMID- 4201854 TI - [Mannich bases of 2,6-disubstituted phenols. VI (author's transl)]. PMID- 4201855 TI - Esterase-2 in Ephestia kuhniella. I. Genetics and characterization. PMID- 4201856 TI - Diversity of RNA sequences in Drosophila melanogaster. PMID- 4201858 TI - On the relationship between the urea-soluble and citric acid-soluble proteins of bovine snout epidermis. PMID- 4201857 TI - Search for nonallelic structural genes for gamma-chains of fetal hemoglobin in some primates. PMID- 4201859 TI - Some observations on future trends in nuclear diagnostic instrumentation. PMID- 4201860 TI - The past seventy-five years in radiotherapy. PMID- 4201861 TI - [Effect of infusion solutions and anabolic steroids in parenteral protein rehabilitation]. PMID- 4201862 TI - Pyruvate kinase from Hydrogenomonas H 16. PMID- 4201863 TI - An enzyme from Bacillus subtilis B with exo-beta-N-acetylmuramidase activity. PMID- 4201865 TI - Delayed cellular immunity response as measured by tuberculin testing of an elderly population. PMID- 4201864 TI - Invertebrate animals--what can they contribute to cancer research? PMID- 4201866 TI - Blood groups and hypertension. PMID- 4201869 TI - [Clinical trial of a new anti-angina agent: perhexiline maleate]. PMID- 4201868 TI - Effect of carotid ligation on cerebral blood flow in baboons. I. Response to altered arterial PCO2. AB - Measurements of cerebral blood flow (CBF) were made in anaesthetized baboons before and after ipsilateral carotid artery ligation and also after bilateral carotid ligation. Results showed that at normocapnia (PaCO(2) 38-39 mmHg) there was little change in cerebral blood flow on ipsilateral carotid ligation, but when both carotid arteries were tied the blood flow to the brain fell significantly. At hypercapnia (PaCO(2) 58-60 mmHg) the CBF/CO(2) gradient fell significantly on ipsilateral carotid ligation; on bilateral carotid ligation there was only minimal rise in cerebral blood flow in response to the rise in PaCO(2). At hypocapnia (PaCO(2) 20-21 mmHg) the gradients of fall in the CBF were similar before and after ipsilateral carotid ligation; after bilateral carotid ligation there was minimal change in the CBF in response to the fall in the PaCO(2). It is suggested that, although cerebral blood flow may be normal after ipsilateral carotid ligation, the circulatory reserve of the brain is not sufficient to meet physiological challenges. This may be the reason for the development of delayed neurological complications after carotid artery ligation. PMID- 4201867 TI - Cerebrovascular response to intracarotid injection of serotonin before and after middle cerebral artery occlusion. AB - The effect of intracarotid injection of serotonin (5-HT) on internal carotid artery flow and oxygen availability (O(2)a) of the cerebral cortex was studied in 10 baboons. Vasoconstriction occurred in the vascular bed of the territory supplied by the injected artery. After one middle cerebral artery was occluded the vasoconstrictor effect of 5-HT was more pronounced, particularly in the non ischaemic hemisphere. The capacity of the cerebral vessels to provide collateral blood flow was reduced in both ischaemic and non-ischaemic areas of brain. As a result of focal cerebral ischaemia, 5-HT may accumulate in the brain and contribute to the progression of infarction. PMID- 4201870 TI - [Clinical trial of a delayed-action Trinitrine in the prevention of angina pectoris]. PMID- 4201871 TI - Inactivation of transforming DNA by ultraviolet light. I. Near-UV action spectrum for marker inactivation. PMID- 4201872 TI - Inactivation of transforming DNA by ultraviolet light. II. Protection by histidine against near-UV irradiation: action spectrum. PMID- 4201873 TI - Inactivation of transforming DNA by ultraviolet light. 3. Further observations on the effects of 365 nm radiation. PMID- 4201874 TI - Repair of ultraviolet-induced DNA damage in the subcellular systems of Bacillus subtilis. PMID- 4201875 TI - The parasexual cycle in Aspergillus flavus. PMID- 4201877 TI - Editorial: Diphosphonate treatment in bone disease. PMID- 4201876 TI - Influence of disodium etidronate on clinical and laboratory manifestations of Paget's disease of bone (osteitis deformans). PMID- 4201878 TI - [Importance of the selection of the donor-recipient pair according to group, type and Rh characteristics for the outcome of keratoplasty]. PMID- 4201879 TI - Toxicity resulting from feeding experimentally molded corn to broiler chicks. PMID- 4201880 TI - Different effects of bursectomy of chickens on immune response to Newcastle disease virus and Salmonella pullorum antigens. PMID- 4201881 TI - The effect of external shell treatments on salmonella penetration of chicken eggs. PMID- 4201882 TI - Epidemiology of Marek's disease (MD): studies on the incidence of MD precipitins in some zoo birds. PMID- 4201883 TI - [Method and controls of cultured cells]. PMID- 4201884 TI - [2 cases of Stevens-Johnson syndrome in children]. PMID- 4201885 TI - [Determination of the effective thyroxin ratio (ETR) (author's transl)]. PMID- 4201886 TI - Discontinuous ficoll gradient separation of normal and malignant cells: cytologic applicability. I. PMID- 4201887 TI - Respiratory rate and succinic dehydrogenase activity in the egg of Ciona intestinalis (ascidian) upon fertilization. PMID- 4201888 TI - [Au antigen in the blood in various groups of healthy children]. PMID- 4201890 TI - Bone formation and calcification in gastric cancer--case report and review of literature. PMID- 4201889 TI - [Kasai operation for biliary atresia (author's transl)]. PMID- 4201891 TI - Semisynthetic penicillins. PMID- 4201892 TI - Monoamine oxidases: versatility of catalytic properties and possible biological functions. PMID- 4201893 TI - Drug metabolism in canine duodenum. PMID- 4201894 TI - Interference of influenza-specific IgA antibodies present in throat washings with isolation of the virus. PMID- 4201895 TI - Chemical structure and biochemical activity of cord factor analogs. 2. Relationships between activity and stereochemistry of the sugar moiety. PMID- 4201896 TI - [Synthesis of a cord factor analogs. I. Study of the selective esterification of trehalose by p-toluene sulfonyl chloride. Demonstration of a nonsymetrical ester:trehalose 2,6-ditosylate]. PMID- 4201898 TI - Structure and configuration of the polyprenoid side chain of dihydromenaquinones from Myco- and Corynebacteria. PMID- 4201897 TI - [Synthesis of cord factor analogs. II. Preparation of trehalose 6,6-dipalmitate by transesterification]. PMID- 4201899 TI - Roentgenographic evaluation in total hip replacement. A study of 100 McKee-Farrar prosthetic replacements. PMID- 4201900 TI - Results of total hip replacement. A clinical follow-up study. PMID- 4201901 TI - Clinical follow-up of total hip replacement. PMID- 4201902 TI - A comparative review of the McKee-Farrar and Charnley total hip prostheses. PMID- 4201903 TI - Three years of experience with total hip replacement. PMID- 4201904 TI - The statistics of the McKee-Farrar method of total hip replacement. PMID- 4201905 TI - Some complications of total hip replacement. PMID- 4201906 TI - Complications after total hip arthroplasty according to Charnley in a Swedish series of cases. PMID- 4201907 TI - A comparison of anubis baboons, hamadryas baboons and their hybrids at a species border in Ethiopia. PMID- 4201908 TI - Adult male replacement in one-male troops of purple-faced langurs (Presbytis senex senex) and its effect on population structure. PMID- 4201909 TI - Contribution to the ecology of Colobus polykomos satanas (Waterhouse, 1838) of Rio Muni, Republic of Equatorial Guinea. PMID- 4201911 TI - Ovarian steroid patterns in peripheral plasma during the menstrual cycle in the rhesus monkey. PMID- 4201910 TI - Cyclic changes in cervical mucus and LH levels in the bonnet macaque (Macaca radiata). PMID- 4201912 TI - Persimmon bezoar in an epiphrenic esophageal diverticulum with endoscopic removal. PMID- 4201913 TI - [Localization of functions in the brain]. PMID- 4201914 TI - Threshold 60-Hz current required for ventricular fibrillation in subjects of various body weights. PMID- 4201915 TI - Preparation HOE 105 (citenazone) in chemoprophylaxis of variola in monkeys: a preliminary communication. PMID- 4201916 TI - Screening of drugs for genetic effects. PMID- 4201917 TI - Follow-up studies in oral lichen planus. PMID- 4201919 TI - Healing of gingival mucoperiosteal flaps after marginal incision in apicoectomy procedures. PMID- 4201918 TI - Morphologic changes in lymph node deposits of oral squamous carcinoma. PMID- 4201920 TI - Mucoepidermoid carcinoma in a lymph node of the parotid sheath simulating condylar tumor. PMID- 4201921 TI - An atypical mandibular tumor caused by Mycobacterium balnei. PMID- 4201923 TI - Deoxyribonucleic acid repair replication in Pseudomonas aeruginosa after sublethal doses of silver sulfadiazine. PMID- 4201922 TI - A simple method of estimating renal clearance by renography. PMID- 4201924 TI - [The influence of plasma expanders on blood type determination, antibody screening tests and compatibility tests]. PMID- 4201925 TI - [Organ transplantation in small laboratory animals]. PMID- 4201927 TI - [Immunology]. PMID- 4201926 TI - [Degradation products of fibrinogen during thrombolysis]. PMID- 4201930 TI - [Appearance in a hospital environment of strains of Pseudomonas aeruginosa resistant to gentamicin. Sensitivity and lysotyping]. PMID- 4201929 TI - [Treatment of bronchial asthma in childhood using disodium cromoglycate]. PMID- 4201931 TI - Malnutrition studies in Macaca mulatta. 3. Effect on cerebral lipids. PMID- 4201933 TI - [Resuscitation in grave eclampsia. Apropos of 11 cases]. PMID- 4201934 TI - [Principal characteristics of heavy chain diseases]. PMID- 4201932 TI - [Influence of temperature during awaking on the response to anesthesia in Drosophila melanogaster]. PMID- 4201935 TI - Lymphocyte transformation and serum agar gel diffusion of rabbits immunized against Neisseria gonorrhoeae and Neisseria catarrhalis. PMID- 4201936 TI - Induction and reversion of the L-form of Neisseria gonorrhoeae. PMID- 4201937 TI - Immunochemical studies of adenosine deaminases from several vertebrates and a mollusc. PMID- 4201939 TI - Isoelectric spectra of different classes of anti-erythrocyte antibodies. PMID- 4201938 TI - Some enzymological properties of a hatching enzyme (chorionase) isolated from the fresh-water teleost, Oryzias latipes. PMID- 4201940 TI - Angina pectoris: diagnosis, evaluation and therapy. PMID- 4201942 TI - Rapid quantitation of the immunopreciptin reaction in agarose gel by electroimmunodiffusion with paper discs. PMID- 4201941 TI - A simple method for the simultaneous detection of human immunoglobulins of both light chain types. PMID- 4201943 TI - [Seroepidemiologic study on perputation of rubella virus in a closed population]. PMID- 4201944 TI - [Serotyping and clinical evaluation of Pseudomonas aeruginosa isolated from the hospital environment and clinical specimens]. PMID- 4201945 TI - [Bacteremia due to Salmonella typhimurium]. PMID- 4201946 TI - Accumulation of histidine, 3-methylhistidine, and homocarnosine in the brains of protein-calorie deficient monkeys. PMID- 4201947 TI - The bithorax complex--a model for cell determination in Drosophila. PMID- 4201949 TI - Morphology and life history of Mitraspora cyprini Fujita, parasitic in the kidney of goldfish. PMID- 4201948 TI - Pseudomonas aeruginosa infections in rats fed on monosodium glutamate with observations on the Pseudomonas flora in their intestines. PMID- 4201950 TI - Penicillin resistance of gonococci in South Vietnam. PMID- 4201951 TI - The diagnosis of farmer's lung. PMID- 4201952 TI - Paradox of the immune response to uncomplicated gonococcal urethritis. PMID- 4201954 TI - A sensitive assay for the determination of dopamine in plasma. PMID- 4201953 TI - The effect of dextran-40 on capillary blood flow and capillary diffusion capacity in the anterior tibial muscle of subjects with intermittent claudication. PMID- 4201955 TI - [Treatment of status epilepticus with Rivotril]. PMID- 4201956 TI - The use of ficoll in the preparation of viable islets of langerhans from the rat pancreas. PMID- 4201957 TI - The growth of mixed population of Lactobacillus casei and nisin producing strain of Streptococcus lactis in batch and continuous cultures. PMID- 4201958 TI - Behaviour of aflatoxins in some meat products. PMID- 4201959 TI - Calcification and ossification in epulides in man (excluding giant cell epulides). PMID- 4201960 TI - The latex agglutination test for the study of the M protein of group A streptococci and of the corresponding antibodies. PMID- 4201961 TI - [Hypergammaglobulinemia in the clinical laboratory. 3. Immunodiffusiometry method (immunograms)]. PMID- 4201962 TI - Hyperalimentation-a review. PMID- 4201964 TI - [Determination of microbial phospholipase activity using the agar diffusion method]. PMID- 4201965 TI - [Values of cholesterol, phospholipids and esterified fatty acids in human serum, following bacterial contamination in vitro]. PMID- 4201963 TI - New jejunostomy feed. AB - Three patients with duodenal fistulae were fed solely with an easily prepared, inexpensive jejunostomy feed for 14, 21, and 23 days respectively. Sodium, potassium, and nitrogen balances became positive, diarrhoea did not develop, and body weight increased. The feed was life-saving: the patients' superficial veins were thrombosed, and percaval feeding was considered undesirable. PMID- 4201967 TI - [Supernumerary tooth in the dentition of the macaca]. PMID- 4201966 TI - The modes of inhibitory effects of PCBs on oxidative phosphorylation of mitochondria. PMID- 4201968 TI - Cerebral edema unresponsive to conventional therapy in neurosurgical patients with unsuspected nutritional failure. PMID- 4201969 TI - Introductory remarks: new agents in psychiatry. PMID- 4201970 TI - Chemistry of trazodone. PMID- 4201971 TI - Pharmacology of trazodone. PMID- 4201972 TI - Clinical experience with a new psychotropic drug, trazodone: a review of literature. PMID- 4201973 TI - Systematic clinical studies with trazodone: methodological aspects. PMID- 4201974 TI - Trazodone in the treatment of organic brain syndromes, with special reference to psychogeriatrics. PMID- 4201975 TI - Trazodone in the treatment of schizophrenias. PMID- 4201976 TI - Trazodone in the treatment of affective disorders. PMID- 4201977 TI - Trazodone and psychosomatic medicine. PMID- 4201978 TI - Trazodone in the treatment of psychoneuroses: a double-blind study. PMID- 4201979 TI - [Bactericidal effect of streptomycin on acid-fast bacilli in the presence of 4 chloroanilid of 5-chlorosalicylic acid]. PMID- 4201980 TI - [Effect of staphylococcin on growth of mycobacteria in vitro]. PMID- 4201981 TI - A comparison of 4-hydroxybenzoic acid hydrazide (PAHBAH) with other reagents for the determination of glucose. PMID- 4201982 TI - A correlation of radiographic, functional, and morphologic changes in baboon lung allografts. A comparison of two immunosuppressive regimens. PMID- 4201983 TI - Transplantation of the lung. Correlation of physiologic, immunologic, and histologic findings. PMID- 4201984 TI - [Role of Australian antigen in the etiology of viral hepatitis]. PMID- 4201985 TI - [Clinical picture and treatment of fibrocavernous tuberculosis of the lungs complicated by nonspecific infection]. PMID- 4201986 TI - Changes in red cell carbonic anhydrase B and serum iodothyronines in hyperthyroid subjects following 131-I treatment. PMID- 4201987 TI - Malaria debriefing: experience with 1552 returnees from Southeast Asia. PMID- 4201988 TI - Clinical and serological responses to plague vaccine U.S.P. PMID- 4201989 TI - Efficacy of surgery for intervertebral discopathy in military personnel. PMID- 4201990 TI - The meaning of mottling on the colloidal radiogold liver scan. PMID- 4201991 TI - Dermatophytes in military personnel. PMID- 4201992 TI - Albert Calmette. The Saigon years 1891-1893: A historical review. PMID- 4201993 TI - Causative factors resulting in the placement of dental restorations: A survey of 8891 restorations. PMID- 4201994 TI - Use of psychotherapeutic drugs in the acute detoxification of heroin addicts. PMID- 4201995 TI - Editorial: The military as a leader in the struggle against atherosclerosis. PMID- 4201996 TI - Mutations as possible replication errors in bacteria growing under conditions of thymine deficiency. PMID- 4201997 TI - Proceedings: Cromolyn sodium. A panel discussion. PMID- 4201998 TI - [Natural infection of Panstrongylus megistus (Burmeister, 1835) by Trypanosoma rangeli (Tejera, 1920) in the interior of the State of Alagoas]. PMID- 4201999 TI - Trypanosoma cruzi infections in Rhodnius prolixus refed on different hosts. PMID- 4202000 TI - [Findings of Rhodnius prolixus eggs naturally parasitized by microhymenoptera]. PMID- 4202001 TI - [Glucose tolerance during intravenous hyperalimentation. Study of patients at a surgical intensive care unit]. PMID- 4202003 TI - Effect of restricted use of phosphate-based detergents on Onondaga Lake. AB - A marked decrease in the concentration of total inorganic phosphate in the epilimnion and hypolimnion of Onondaga Lake, New York State, has been observed during the 1(1/2) years between July 1971 and January 1973. This decrease has been correlated to the implementation of phosphate-limiting legislation. The response of characteristic plankton species has been investigated. PMID- 4202002 TI - Diphtheria. PMID- 4202004 TI - Biliary atresia: the current state of confusion. PMID- 4202006 TI - [Lyell's syndrome with uncompensated diabetes]. PMID- 4202007 TI - Bovine mycoplasmas: serological studies by double immunodiffusion, growth precipitation and growth inhibition. PMID- 4202005 TI - [Study of the antagonism between Lactobacillus, E. coli and Bac. Anthracoides]. PMID- 4202008 TI - Proteases of Clostridium botulinum. IV. Inhibitors against proteases from Clostridium botulinum. PMID- 4202009 TI - Serum luteinizing hormone concentrations in male monkeys (Macaca fascicularis). PMID- 4202010 TI - Fractionation of Listeria monocytogenes serotype 5. PMID- 4202011 TI - [Serumalbumin and IgA, IgG and IgM immunoglobulin concentration in gastric juice of normal man evaluated by the single radial immunodiffusion method (author's transl)]. PMID- 4202012 TI - [Immunochemical study of foetal pepsinogen (author's transl)]. PMID- 4202013 TI - Saturation in the competitive protein-binding assay of serum thyroxine. PMID- 4202014 TI - The presence of furan derivatives in patients receiving fructose-containing solutions intravenously. PMID- 4202015 TI - Determination of serum glucose with o-toluidine without glacial acetic acid. PMID- 4202017 TI - Selection for altered recombination frequency in Drosophila melanogaster. PMID- 4202016 TI - Serum IgG, IgM and IgA concentration determined by the "linear plate" immunodiffusion technique in a normal population. PMID- 4202018 TI - Ultrastructure of the 5S RNA locus in salivary gland chromosomes of drosophila melanogaster. PMID- 4202019 TI - Syntheses of the beta-D-glucosides of 4- and 5-hydroxy-1-naphthyl N methylcarbamate. PMID- 4202020 TI - A study of lipoxidase in pea seeds and seedlings. PMID- 4202021 TI - Nutritive value of processed Saccharomyces cerevisiae, Scenedesmus obliquus and Spirulina platensis as measured by protein synthesis in vitro in rat skeletal muscle. PMID- 4202022 TI - Clinicopathologic conference: Acute illness with elevated serum amylase. PMID- 4202023 TI - Oxypertine and primate behaviour. PMID- 4202024 TI - The basic pharmacology of oxypertine. PMID- 4202025 TI - [Possibility of erroneous interpretation of Rh-reference of blood in patients with autoerythrocytic aggression]. PMID- 4202026 TI - [Unusual case of von Recklinghausen's neurofibromatosis with x-ray evidence of manifestations of the disease in the thorax, mediastinum, skull, esophagus, stomach and colon]. PMID- 4202027 TI - [Erythromycin sensitivity of gonococcal strains isolated in 1965-1966 and in 1971]. PMID- 4202028 TI - [Clinical diagnostic study of the microcirculation in the conjunctival vessels in pathological pregnancy]. PMID- 4202031 TI - [Talocrural arthrodesis]. PMID- 4202029 TI - Defective drug metabolism in rat liver in endotoxin shock. PMID- 4202032 TI - Biosynthesis of mycolic acids. Formation of a C32 beta-keto ester from palmitic acid in a cell-free system of Corynebacterium diphtheriae. PMID- 4202033 TI - Studies on the biosynthesis of glucolipid in Tetrahymena pyriformis. PMID- 4202034 TI - [Photochromic system of regulation and its role in the development of microorganisms]. PMID- 4202035 TI - Responses of trigeminal units in the monkey bulbar lateral reticular formation to noxious and non-noxious stimulation of the face: experimental and theoretical considerations. PMID- 4202036 TI - Interhemispheric comparison of mirror image stimuli in chiasm-sectioned monkeys. PMID- 4202037 TI - The relationship of subsurface cisternae and cisternal organs to symmetrical axon terminals in the primate sensorimotor cortex. PMID- 4202039 TI - Soft tissue sarcomas: an outline guide to management. PMID- 4202038 TI - [Non-homogenous irrigation of the myocardium and its importance in cardiac therapeutics]. PMID- 4202041 TI - Biochemical tests for cancer. PMID- 4202042 TI - Newer methods for evaluating thyroid nodules. PMID- 4202040 TI - The management of chronic pain. PMID- 4202043 TI - Carcinoma of the stomach. PMID- 4202044 TI - Classics in oncology: Johannes Muller (1801-1858). PMID- 4202046 TI - Sporogony of Leucocytozoon spp. in mammalophilic simuliids. PMID- 4202045 TI - Unproven methods of cancer management. Gerson method of treatment for cancer. PMID- 4202048 TI - [Alpha-fetoprotein in embryonal cell carcinoma of the testis]. PMID- 4202047 TI - Correlations between pathological changes in the hind paws of rats with adjuvant arthritis and their response to anti-inflammatory and analgesic drugs. PMID- 4202050 TI - Serological and prognostic significance of partial absorption anti-human globulin test for incomplete Rh antibodies. PMID- 4202049 TI - Enteric infections in captive monkeys. PMID- 4202051 TI - Hepatitis associated antigen amongst blood donors in Delhi by counter electrophoresis. PMID- 4202053 TI - The scope of oral glibenclamide in the non-ketotic young diabetics. PMID- 4202052 TI - A follow-up study on diphtheria carriers among children below 5 years in a rural population of Lucknow District. PMID- 4202054 TI - Some serological studies on Bacteroides corrodens. PMID- 4202055 TI - Synthesis of lipoic acid by Streptococcus faecalis 10C1 and end-products produced anaerobically from low concentrations of glucose. PMID- 4202057 TI - Intestinal fistulae. PMID- 4202056 TI - Isolation and partial characterization of a temperature-sensitive mutant of Bacillus subtilis impaired in the development of competence for genetic transformation. PMID- 4202058 TI - The healthy male carrier of the gonococcus. PMID- 4202059 TI - [Bacteriological studies of feces in patients with preternatural anus]. PMID- 4202060 TI - [Applicators for intracavitary gammatherapy of cervical cancer on the principle of simple afterloading]. PMID- 4202061 TI - [High-energy electron treatment of tumors of the eye and orbit]. PMID- 4202062 TI - Thought for food. PMID- 4202063 TI - Intravenous feeding of the newborn. PMID- 4202064 TI - IgA deficiency and autoimmune haemolytic anaemia. PMID- 4202065 TI - Genetic dissection of behavior. PMID- 4202066 TI - [Experience with biochemical control of vitaminotherapy (B1, B2, C) in typhoid paratyphoid diseases]. PMID- 4202067 TI - [Current concepts of insulin resistance and causes of its development]. PMID- 4202068 TI - Importance of dilantin blood levels in managing epilepsy. PMID- 4202069 TI - [Improvement in the methods of diagnosing listeriosis]. PMID- 4202070 TI - [Phagocytosis of Listeria by macrophages in vitro]. PMID- 4202071 TI - [Taxonomic position of the causative agent of honey bee paratyphoid (a review of the literature)]. PMID- 4202072 TI - [Study of beef infested with Sarcocystis]. PMID- 4202073 TI - [Some biological properties of Listeria monocytogenes]. PMID- 4202074 TI - [Pathomorphology in experimental brucellosis of yaks]. PMID- 4202075 TI - [Experience in using specific lactoglobulins]. PMID- 4202076 TI - Is there a protein problem? PMID- 4202077 TI - [Release, floating and sedimentation of microorganisms in the room air as the basis for prevention and fight against air-borne infections]. PMID- 4202078 TI - [Identification and determination of organophosphate insecticides and carbaryl on ready-made thin-layer plates]. PMID- 4202079 TI - [Effect of different rations on the development of ciliata in the rumen]. PMID- 4202080 TI - [Test series for the general inhibitor test on defined animal material]. PMID- 4202081 TI - [Behavior of various plasma enzymes and electrolytes as well as of glucose, nonesterified fatty acids and lactate in pigs during the stabling following transport to the abattoir]. PMID- 4202082 TI - The relation of starvation to hypoglycaemia and adrenocortical activity in newborn and six-week-old piglets. PMID- 4202083 TI - [Circadian ryhthm of plasma glucose and insulin in young miniature pigs]. PMID- 4202084 TI - Permeability of the mammary gland to large antibiotic molecules. PMID- 4202085 TI - Observations on the synchronization of oestrus in Sarda sheep. PMID- 4202087 TI - [Nontraumatic ruptures of the heart atrium in the dog]. PMID- 4202086 TI - Changes in the cell pattern in vaginal smears of cattle during pregnancy. PMID- 4202089 TI - Electron-microscopic changes of the liver and kidneys in chickens treated with tannic acid. PMID- 4202088 TI - Congenital heart abnormalities in the cat. A description of sixteen cases. PMID- 4202090 TI - An electron microscopical study of the cerebral cortex of the calf. 1. The normal calf. PMID- 4202091 TI - [Change in the antigenic composition of the hypophysis of Gobius melanostomus in relation to its sexual cycle]. PMID- 4202092 TI - The concept of population in biology. A logical analysis with a suggestion to diminish the confusion of thought. PMID- 4202093 TI - Ultrastructural features of phytohemagglutinin and concanavalin A-responsive lymphocytes in chronic lymphocytic leukemia. PMID- 4202094 TI - Diisopropylfluorophosphate uptake by granulocytopoietic cells in chronic myeloid leukaemia and in normal individuals. PMID- 4202096 TI - Splenic function and infection in sickle cell anemia. PMID- 4202095 TI - Serum haemopexin concentration in patients with various haemoglobinopathies. Effect of splenectomy. PMID- 4202097 TI - Ribonucleic acid and phytohemagglutinin on rat leukocyte cultures within diffusion chambers. PMID- 4202098 TI - Study of the effect of actinomycin D on the thrombocytopoiesis of mice, using 75Se-labelled methionine. PMID- 4202099 TI - [Type II glycogenosis. Example of congenital lysosomal disease]. PMID- 4202100 TI - Experimental iris suture observed by electronmicroscope. A preliminary report. PMID- 4202101 TI - Structure and function of nucleosides and nucleotides. PMID- 4202102 TI - Recent results in insect pheromone chemistry. PMID- 4202103 TI - Solid phase synthesis of peptides with carboxyl-terminal amides--thyrotropin releasing factor (TRF). PMID- 4202104 TI - Stereochemistry of the coenzyme-B12-dependent methylamalonyl-CoA-mutase reaction. Investigation with ethylmalonyl-CoA. PMID- 4202105 TI - Nuclear medicine and radiochemistry. PMID- 4202107 TI - 5'-Nitrates of pyrimidine nucleosides: nitric acid analogs of nucleotides. PMID- 4202106 TI - Chemistry and significance of the carbohydrate moieties of human serum glycoproteins. PMID- 4202109 TI - The Lutheran, Duffy and Kell blood groups. PMID- 4202108 TI - Methoxymethyl isocyanate as a new agent for reversible protection of SH groups in protein and peptide chemistry. PMID- 4202110 TI - [The problem of the urethral biozoonosis of the healthy male]. PMID- 4202111 TI - [The etiology of urethritis and prostatitis]. PMID- 4202113 TI - Ag (x, y, a1, z, t) antigens in a Japanese population. PMID- 4202112 TI - Authropometric and genetic studies in a Russian Old Believer population. PMID- 4202114 TI - An immunological approach to the study of inherited differences in the activity of human erythrocyte phosphoglucose isomerase. PMID- 4202115 TI - Absorption studies of iron and vitamin B12 by INMAS whole body counters. PMID- 4202116 TI - Media for the isolation and preservation of N. gonorrhoeae. PMID- 4202117 TI - Isolation of Kaisodi virus from ixodid ticks in he Kyasanur Forest disease area of Shimoga district, Mysore State, India. PMID- 4202118 TI - Immunoglobulin specificity of Rh antibodies. PMID- 4202119 TI - Localization of sucrase in the microvillous membrane of rabbit intestinal mucosal cells. PMID- 4202120 TI - Limited proteolysis of human IgG by fruit bromelain. PMID- 4202122 TI - Neutral and amino sugar composition of thyroglobulin. Comparison of the compositions of different fractions of hog thyroglobulin and of thyroglobulins from various animal species. PMID- 4202121 TI - Difference-spectrophotometry of the interaction of cycloheptaamylose with saccharifying alpha-amylase from Bacillus subtilis. PMID- 4202123 TI - Studies on mammalian glycosidases. V. Effects of metal ions upon acidic and neutral alpha-glucosidases, beta-galactosidases, and alpha-mannosidases in liver extract of rabbit. PMID- 4202124 TI - Constant irrelevant cues and stimulus generalization in monkeys. PMID- 4202126 TI - [Malignant pleuropulmonary neurofibromatosis (von Recklinghausen disease) (author's transl)]. PMID- 4202125 TI - Effects of various coronary vasodilators on myocardial oxygen consumption. PMID- 4202127 TI - [Bacteriological examination for gonorrhoea]. PMID- 4202129 TI - [The incidence of gonorrhoea in Denmark 1957-1971]. PMID- 4202128 TI - [Incidence of gonorrhoea in women referred to a gynecological department. Routine study with reference to asymptomatic cases]. PMID- 4202130 TI - [Prostaglandins in inflammation--new perspectives]. PMID- 4202131 TI - [Folate levels during long-term therapy with trimethoprim and sulphadiazine]. PMID- 4202132 TI - [Ampicillin treatment of gonorrhea in a prison-material]. PMID- 4202134 TI - Fine-structural changes of the synovial membrane in arthrosis deformans. PMID- 4202133 TI - Glomerulonephritis associated with (infected) ventriculo-atrial shunt. PMID- 4202135 TI - [Morphological differences in the aorta of rat following experimental ligation of the thoracic duct (author's transl)]. PMID- 4202136 TI - [Lipids in atheromatous pulp of human coronary arteries. Thin-layer chromatographic investigations (author's transl)]. PMID- 4202137 TI - [Intravital uptake of trypan blue in the epithelial cells of the proximal renal tubule following sublimate intoxication and subsequent treatment with L-thyroxine (author's transl)]. PMID- 4202138 TI - Trace elements in human nutrition. Report of a WHO expert committee. PMID- 4202139 TI - Notes on the use of stereological methods in comparative placentology. PMID- 4202141 TI - [Clinical and laboratory contribution to the prevention of fetal hemoblastosis]. PMID- 4202140 TI - Ventricular tracking pacemaker and teletransmitter follow-up system. PMID- 4202142 TI - [Our experience with prevention of fetal erythroblastosis due to Rh]. PMID- 4202143 TI - Thyrotropin-releasing hormone as a pituitary-function indicator. A comparison with other tests. PMID- 4202144 TI - Hypersensitivity pneumonitis in the monkey. PMID- 4202145 TI - [Characteristics of the architectonics of the arterial bed of the pia mater in cat and monkey cerebellum]. PMID- 4202148 TI - Amino acid transport in the cornea. I. 3-Aminoisobutyric acid uptake in the toad. PMID- 4202149 TI - Encephalitozoonosis (nosematosis) of the cornea. PMID- 4202147 TI - Cyanophages-viruses attacking blue-green algae. PMID- 4202150 TI - Use of horseradish peroxidase in identification of serum antibodies and immune complexes. PMID- 4202151 TI - Metabolism and metabolic action of lead and other heavy metals. PMID- 4202152 TI - Toxicity of beryllium and other elements in missile propellants. PMID- 4202146 TI - Chemistry and biology of the polyene macrolide antibiotics. PMID- 4202153 TI - [Oral carbenicillin treatment with carindacillin (author's transl)]. PMID- 4202155 TI - Immune response of guinea pigs to common enterobacterial antigen. PMID- 4202154 TI - Cessation of deoxyribonucleic acid polymerase activity in amino acid-starved Tetrahymena pyriformis. PMID- 4202156 TI - Touch epilepsy. PMID- 4202157 TI - Immunologic homogeneity and electrophoretic heterogeneity of mouse melanoma tyrosinases. PMID- 4202158 TI - Pulmonary arterial pressure and structure in the baboon Papio papio. PMID- 4202159 TI - The sensitivity of the colloidal carbon technique in measuring pulmonary vascular permeability changes. PMID- 4202160 TI - Cavitating pulmonary infarct: an unusual complication of parenteral alimentation. PMID- 4202161 TI - Letter: Intragastric versus nasojejunal feeding of low-birth-weigh infants. PMID- 4202162 TI - Cellular and humoral immune response to group B streptococci. PMID- 4202163 TI - Mangement of intraurethral condyloma acuminatum. PMID- 4202164 TI - Chemicals used topically for ringworm in Australia. PMID- 4202165 TI - Letter: Prostaglandins, nutmeg and diarrhea. PMID- 4202166 TI - Locomotor affinities of Hominoid tali from Kenya. PMID- 4202167 TI - Gonorrhea amnionitis. PMID- 4202168 TI - Amniotic fluid evaluation after intrauterine transfusion. PMID- 4202169 TI - Optimal utilization of Rh immunoglobulin in induced abortion. PMID- 4202170 TI - [Advances in cardiology. Arteriosclerosis, coronary disease]. PMID- 4202171 TI - [Serum or plasma viscosimetry in normal subjects, cord blood and patients with paraproteinemias]. PMID- 4202172 TI - [A case of multiple jaw lesions in generalized neurofibromatosis Recklinghausen]. PMID- 4202173 TI - [Alveolalgia and alveolitis]. PMID- 4202174 TI - [Bronchodilating agents. Prevention and therapy]. PMID- 4202175 TI - Studies on the phospholipase A2 in pyloric caeca of the starfish Asterina pectinifera. PMID- 4202176 TI - Cell-free translation of influenza virus messenger RNA. PMID- 4202177 TI - [Case of macroglobulinemic reticulolymphomatosis]. PMID- 4202178 TI - [Bacteriological examination for Mycobacterium tuberculosis in the middle-aged and elderly]. PMID- 4202179 TI - [Treatment of peptic ulcer by transduodenal feeding]. PMID- 4202180 TI - Ultrastructural basis of toxic hepatitis. PMID- 4202181 TI - Adverse reactions to intravenous diazepam: a report from the Boston Collaborative Drug Surveillance Program. PMID- 4202182 TI - Transfusion with wrong type of blood claimed too late. PMID- 4202183 TI - [Technics of detection of Australia antigen and corresponding antibodies in blood transfusion centers]. PMID- 4202184 TI - [Blood groups of Bantu populations in Angola, together with a contribution on the estimate of fatherhood probability in expert testimonies of Negroes as possible fathers]. PMID- 4202185 TI - Problems and progress in physiological psychology. PMID- 4202186 TI - Proceedings: Cancer of the kidney--radiation therapy and its indications in non Wilms' tumors. PMID- 4202188 TI - Proceedings: Radiation therapy in malignant testis tumors. I: Seminoma; II: Carcinoma. PMID- 4202187 TI - Proceedings: Diagnosis and staging of prostatic carcinoma. PMID- 4202189 TI - Extended combination therapy of childhood rhabdomyosarcoma. PMID- 4202190 TI - Prognostic signs and the management of the mycosis fungoides. PMID- 4202191 TI - A controlled study of isolation and endogenous microbial suppression in acute myelocytic leukemia patients. PMID- 4202192 TI - Binding of tryptophan to plasma proteins in several species. PMID- 4202194 TI - Characterization of an unstable carbonic anhydrase (CAII) variant in the guinea pig (Cavia porcellus). PMID- 4202193 TI - The identification of two protease inhibitors in Drosophila melanogaster. PMID- 4202196 TI - [Oxygen uptake and heat production of cynomolgus monkey (Macaca irus) in a primate restraining chair at ambient temperature of 25 degrees C and 10 degrees C (author's transl)]. PMID- 4202195 TI - [Therapy in idiopathic retroperitoneal fibrosis]. PMID- 4202197 TI - [A newly-devised squeezing cage for monkeys (author's transl)]. PMID- 4202198 TI - Thymineless death in Lactobacillus acidophilus R-26. II. Factors determining the rate of the reproductive inactivation. PMID- 4202199 TI - Productivity and heat generation of fermentation under oxygen limitation. PMID- 4202200 TI - The interaction of protein substrates (antigens) during an in vitro degradation by rabbit cathepsin D. PMID- 4202201 TI - Regulation of biosynthesis of excessive metabolites. XIV. Incorporation of (U 14C) asparagine into the molecule of tetracycline. PMID- 4202202 TI - Increased resistance to malaria after Mycobacterium tuberculosis infection. PMID- 4202203 TI - Personal health expenses among rural communities of North Arcot District. PMID- 4202204 TI - Nutritional assessment of rural pre-school children. PMID- 4202205 TI - The effect of trimethoprim on the activity of sulfonamides and antibiotics in experimental infections. PMID- 4202206 TI - Antibacterial action of trimethoprim-sulfamethoxazole. PMID- 4202207 TI - Distribution of trimethoprim-sulfamethoxazole in tissues of rhesus monkeys. PMID- 4202208 TI - Various regimens of trimethoprim-sulfamethoxazole used in the treatment of gonorrhea. PMID- 4202209 TI - Trimethoprim-sulfamethoxazole in the treatment of infections of the ears, nose, and throat. PMID- 4202211 TI - Trimethoprim-sulfamethoxazole in the treatment of typhoid and paratyphoid fevers. PMID- 4202210 TI - Effects of trimethoprim and sulfisoxazole, alone and in combination, on growth and carriage of Neisseria meningitidis. PMID- 4202212 TI - Treatment of chronic carriers of Salmonella typhi and Salmonella paratyphi B with trimethoprim-sulfamethoxazole. PMID- 4202213 TI - Phenylmorphan agonists-antagonists. PMID- 4202215 TI - Synthesis and antimalarial effects of 1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3 piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine and related substances. PMID- 4202214 TI - Synthesis and antibacterial activity of some substituted 4-quinolone-3-carboxylic acids. PMID- 4202216 TI - The lambda head-tail joining reaction: purification, properties and structure of biologically active heads and tails. PMID- 4202217 TI - Distribution of histone messenger RNA among free and membrane-associated polyribosomes of a mouse myeloma cell line. PMID- 4202218 TI - Amino acid sequence of lysozyme from baboon milk. PMID- 4202219 TI - Chemical modification of lincomycin: synthesis and bioactivity of selected 2,7 dialkylcarbonate esters. PMID- 4202221 TI - Electrokinetic studies of bacteria. 3. Effect of polyvalent metal ions on electrophoretic mobility and growth of Streptococcus faecalis. PMID- 4202220 TI - Mesoionic purinone analogs. IV. Synthesis and in vitro antibacterial properties of mesoionic thiazolo(3,2-a)pyrimidin-5,7-diones and mesoionic 1,3,4 thiadizolo(3,2-a)pyrimidin-5,7-diones. PMID- 4202222 TI - Microbial food chains and food webs. PMID- 4202223 TI - [Chemical dissolution of kidney stones. Experimental and clinical results. I. (author's transl)]. PMID- 4202224 TI - Dual classification of tympanoplasty. PMID- 4202225 TI - Conserved terminal sequence in 18SrRNA may represent terminator anticodons. PMID- 4202227 TI - Multiple heavy chains classes and light chain types on surfaces of cultured human lymphoid cells. PMID- 4202226 TI - DNA-binding proteins specific for cells infected by adenovirus. PMID- 4202228 TI - Successive visual discrimination performance in the monkey with brief stimuli. PMID- 4202229 TI - Measurement of pituitary hormones: clinical applications. 4. Thyroid stimulating hormone. PMID- 4202230 TI - Organochlorine pesticide residues and polychlorinated biphenyls in human milk, Colorado--1971-72. PMID- 4202231 TI - Eggshell thinning, chlorinated hydrocarbons, and mercury in inland aquatic bird eggs, 1969 and 1970. PMID- 4202233 TI - Organochlorine pesticides and polychlorinated biphenyls in black duck eggs from the United States and Canada--1971. PMID- 4202232 TI - International cooperative study of organochlorine and mercury residues in wildlife, 1969-71. PMID- 4202234 TI - [Therapeutic results with the hypotensive agent Declinax (debrisoquin) in mild and medium forms of hypertension]. PMID- 4202235 TI - [Distribution of ABO, rhesus, MN and P blood system groups among patients with blood system diseases]. PMID- 4202236 TI - Actinic keratoses in Bantu albinos. Clinical experiences with the topical use of 5-fluoro-uracil. PMID- 4202237 TI - A one-year survey of a rural orthopaedic clinic in Zululand. PMID- 4202238 TI - Age-induced changes of cerebral arteries in rats. An electron microscope study. PMID- 4202239 TI - Dysentery and colienterocolitis. Some aspects of pathogenesis and pathological anatomy. PMID- 4202240 TI - Dysplastic gliosis (spongioblastosis) and the Rosenthal fibres. Pathogenetic contributions. PMID- 4202241 TI - Morphogenesis of plasmatic arterionecrosis as the cause of hypertensive intracerebral hemorrhage. PMID- 4202242 TI - [Ultrastructure of pituitary adenomas in Cushing's syndrome after adrenalectomy (author's transl)]. PMID- 4202243 TI - [Ultrastructural differentiation of pheochromocytoma (author's transl)]. PMID- 4202244 TI - [Differences in lipid metabolism between normal intima and atherosclerotic lesions in human femoral artery (author's transl)]. PMID- 4202245 TI - [Pathology of the "Fallot lung". Qualitative and quantitative postoperative studies in patients with tetralogy of Fallot (author's transl)]. PMID- 4202246 TI - Upper gastrointestinal radiologic findings in hyperlipoproteinemic subjects. PMID- 4202247 TI - Protein--energy deficiency in nonhuman primates: biochemical and morphological alterations. PMID- 4202249 TI - Essential fatty acid deficiency in red cells after thermal injury: correction with intravenous fat therapy. PMID- 4202248 TI - Evidence for intestinal malabsorption of iodine in protein-calorie malnutrition. PMID- 4202250 TI - Protein-calorie malnutrition in Egypt. I. Immunoelectrophoretic studies on urinary proteins. PMID- 4202251 TI - Pulmonary aspergillosis caused by Aspergillus fischeri var. spinosus: report of a case and value of serologic studies. PMID- 4202252 TI - Monoclonal IgG-lysozyme (muramidase) complex in acute myelomonocytic leukemia: an unusual finding. PMID- 4202253 TI - Multiple diverticula of the esophagus. PMID- 4202254 TI - Intestinal neurofibromas in von Recklinghausen's disease. PMID- 4202255 TI - Serum and amniotic fluid lactic dehydrogenase in pregnant women. PMID- 4202256 TI - Chronic manganese intoxication. PMID- 4202257 TI - Editorial: Nourishment in illness. PMID- 4202258 TI - Some aspects of parenteral nutrition. PMID- 4202259 TI - Quartan malarial infections in Aotus trivirgatus with special reference to renal pathology. PMID- 4202261 TI - Candida albicans septicaemia during first half of pregnancy successfully treated with 5-fluorocytosine. PMID- 4202260 TI - Combined test for assessment of anterior pituitary function. AB - A combined test consisting of the simultaneous administration of insulin, thyrotrophin-releasing hormone (TRH), and luteinizing hormone and follicle stimulating hormone-releasing hormone (LH/FSH-RH) was performed in 24 people. Eleven of these also had the three individual tests performed separately, and the remaining 13 had a separate test of either LH/FSH-RH and TRH together or singly at a later date. In both normal people and patients, whether the tests were performed alone or in combination, no difference was found between the hormone responses (growth hormone, cortisol, LH, FSH, thyroid-stimulating hormone) seen to these stimuli.It is proposed that combined administration of insulin and the hypothalamic releasing hormones may be used as a single test for the assessment of anterior pituitary function. The test is convenient and time saving, and with care can be performed in outpatients. PMID- 4202262 TI - Editorial: Struggle with malaria. PMID- 4202263 TI - Letter: Brachial plexus palsy after parenteral feeding. PMID- 4202264 TI - New type of allergic asthma due to IgG "reaginic" antibody. AB - This study was undertaken to examine the possibility that IgE is not the only immunoglobulin responsible for immediate allergic reactions. A group of asthmatics were investigated in whom immediate allergic reactivity of the bronchi to common inhalant allergens had been confirmed by provocation tests. Their sera were fractionated and the reaginic activity of the immunoglobulin classes was studied by passive cutaneous anaphylaxis testing in monkeys. The results showed that the immediate allergic reactions were due to IgE antibodies in most patients, but there was a group with reactions due to short-term anaphylactic IgG antibodies. It was not possible to inhibit the IgG-mediated responses with disodium cromoglycate. As these two groups had clearly different serum IgE levels the estimation of IgE provided an important guide to the management of these patients. PMID- 4202265 TI - Cefoxitin, a new semi-synthetic cephamycin: an in-vitro and in-vivo comparison with cephalothin. AB - The activity of cefoxitin was compared with that of cephalothin against 229 bacterial strains. Cefoxitin was more active against most Gram-negative strains, notably against indole-producing Proteus spp., which are usually resistant to the cephalosporins. Cefoxitin was not susceptible to any significant extent to degradation by beta-lactamases produced by Gram-negative organisms. Against Gram positive organisms, however, cefoxitin was considerably less active than cephalothin, but minimum inhibitory concentrations for Staphylococcus aureus were well within therapeutically attainable blood levels.Pharmacokinetic studies in 18 volunteers showed a higher and longer sustained antibiotic activity in serum and urine after injections of cefoxitin than after equal doses of cephalothin. Urinary recovery of cefoxitin activity was also much higher than that of cephalothin. No evidence of toxicity due to cefoxitin was found. Cefoxitin was slightly less painful after intramuscular injection than cephalothin. PMID- 4202266 TI - Letter: Thyrotrophin-releasing hormone, prolactin, and cholesterol. PMID- 4202267 TI - [Production statistics in diagnosis and therapy]. PMID- 4202268 TI - [Comparative leucocyte counting from vein, ear lobe and finger (author's transl)]. PMID- 4202270 TI - Prostaglandin F2a and primate corpus luteum: a correlation of structure and function. PMID- 4202269 TI - [Utilisation and metabolic behaviour of sorbitol during long-term parenteral perfusions (author's transl)]. PMID- 4202271 TI - Postoperative intraperitoneal adhesions: a double-blind assessment of their prevention in the monkey. PMID- 4202272 TI - The effect of a chemically defined diet on the faecal flora and faecal steroid concentration. AB - The consumption of a chemically defined diet altered both the faecal flora and faecal steroids. Enterobacteria increased while enterococci and other lactic acid bacteria decreased in number. No other obvious change occurred. However, the alteration in the degree of degradation of the faecal neutral steroids may reflect some alteration in the anaerobic flora. Total excretion of both acid and neutral steroids was also reduced. On cessation of the diet both faecal flora and faecal steroids reverted to levels before the diet. PMID- 4202273 TI - Proceedings: The distribution of vasoactive intestinal peptide (VIP) in the primate gastrointestinal tract and characterization of VIP from human tumours. PMID- 4202274 TI - Proceedings: Comparative effect of intravenous and oral nutrition of intestinal adaptation. PMID- 4202276 TI - Pseudomonas vertebral osteomyelitis in heroin addicts. Report of five cases. PMID- 4202275 TI - Mental disorders associated with industrial head injury. PMID- 4202277 TI - Avulsion of lumbar roots complicating fracture of the pelvis. PMID- 4202278 TI - Gold distribution in whole blood during chrysotherapy. PMID- 4202279 TI - Beta-glucuronidase deficiency mucopolysaccharidosis: methods for enzymatic diagnosis. PMID- 4202280 TI - Neuritic (senile) plaques and filamentous changes in aged rhesus monkeys. PMID- 4202281 TI - [Home nursing and professional nursing]. PMID- 4202282 TI - [Bedside nursing. Tube-feeding of an aged patient with a cognition disorder]. PMID- 4202283 TI - [Assistance to a diabetic patient lacking will power resulting in repeated hospitalization]. PMID- 4202284 TI - [Use of a position block in nursing of patients with cervical cord injuries]. PMID- 4202285 TI - [Nursing technics concerning the comfort of the patient. 1]. PMID- 4202286 TI - [Nursing conference. 11. Nursing plan for a child who would not communicate with anyone other than members of her family]. PMID- 4202287 TI - [Coping with physical symptoms in metastatic breast cancer]. PMID- 4202288 TI - [Survey on the attitude of patients with chronic disease under long term care. Survey on tuberculosis patients]. PMID- 4202289 TI - [National health expenditures]. PMID- 4202290 TI - [Social medicine observed in geriatric care]. PMID- 4202291 TI - [Pathophysiology of diseases. 8. Dizziness]. PMID- 4202292 TI - [Introduction to the study of human development. 4. Formation of interpersonal relationship and child development]. PMID- 4202293 TI - [Transfer technics. 4. Methods of raising the patient out of bed]. PMID- 4202294 TI - [The relationship between the length of the lower extremity and the Brown traction stand]. PMID- 4202295 TI - [The theory of "assistance" in nursing. II. Re-evaluation of practical methods of assistance. 6]. PMID- 4202296 TI - [Psychology in nursing relationship. 11. Abnormal psychology and ambivalence in interpersonal relationship]. PMID- 4202297 TI - [Death and nursing. 11. Patient's family]. PMID- 4202298 TI - [Medicine and civilization. 11. Biometeorology]. PMID- 4202299 TI - [Obesity as a socioeconomic and a clinical problem]. PMID- 4202300 TI - [Disorders of lipid metabolism--hyperlipoproteinemia]. PMID- 4202301 TI - [Psychological aspects of obesity]. PMID- 4202302 TI - [Diet therapy of diabetes mellitus]. PMID- 4202303 TI - [Late syndrome of diabetes mellitus]. PMID- 4202304 TI - [Gout]. PMID- 4202305 TI - [Biochemical revolution]. PMID- 4202306 TI - [Radiation protection dosimetry: regulations, methods and results]. PMID- 4202307 TI - [Comprehensive nursing care. VIII. Role of nursing service in comprehensive nursing care]. PMID- 4202308 TI - [A woman reaches her 50th year]. PMID- 4202309 TI - [Problems of the older nurse in the modern hospital system]. PMID- 4202311 TI - [The European woman of today]. PMID- 4202310 TI - [Service of love or slave service? Thoughts on the status of women in today's society]. PMID- 4202313 TI - [The bachelor girl]. PMID- 4202312 TI - [The single woman--in society and in the hospital]. PMID- 4202314 TI - [Does the man have a chance?]. PMID- 4202315 TI - [Hormonal balance eases the aging process]. PMID- 4202316 TI - [Unification of the examination system in nursing]. PMID- 4202317 TI - [Psychological stress for the child in the hospital]. PMID- 4202318 TI - [Therapy of epilepsy in children]. PMID- 4202319 TI - [Causes and treatment of comatous conditions in children]. PMID- 4202320 TI - [Poisoning in childhood]. PMID- 4202321 TI - [Do not overfeed infants]. PMID- 4202322 TI - [Cryogenic treatment in medicine]. PMID- 4202323 TI - [Campaign for a healthy life]. PMID- 4202324 TI - Editorial: Gonococcocidal action of copper. PMID- 4202325 TI - Editorial: Gallstones and estrogens. PMID- 4202327 TI - A fate map of larval organs of Drosophila and preblastoderm determination. PMID- 4202326 TI - Letter: Diagnosis of Fabry's disease by tear alpha-galactosidase A. PMID- 4202328 TI - Thymosin-producing cells of the thymus. PMID- 4202329 TI - The effect of capping H-2 antigens on the susceptibility of target cells to humoral and T cell-mediated lysis. PMID- 4202330 TI - Hypothalamic interaction between prostaglandins and catecholamines in promoting gonadotrophin secretion for ovulation. PMID- 4202331 TI - Regulation of rat liver beta-hydroxy-beta-methylglutaryl-CoA reductase activity by cholesterol. PMID- 4202332 TI - Lead poisoning in childhood: a case report with environmental implications. PMID- 4202333 TI - Immunoglobulins in normal porcine tracheobronchial secretions. PMID- 4202335 TI - Pathology of Bolivian hemorrhagic fever in the rhesus monkey. AB - Gross and microscopic lesions associated with Bolivan hemorrhagic fever virus infection in the rhesus monkey were studied in 10 animals which died following inoculation. Gross lesions included skin rash, lymphadenopathy, splenomegaly, meningeal edema, hydropericardium and enlarged friable livers. Hemorrhagic manifestations of the infection were not consistently observed, but hemorrhages were present in the skin, heart, brain and nares in some monkeys. Histopathologic lesions were fairly consistent. Hepatic necrosis with the presence of acidophilic hyaline bodies, necrotizing enteritis, epithelial necrosis and adrenal cortical necrosis were present in all monkeys. Those monkeys which died after the seventeenth day of infection had nonsupurative meningoencephalitis; lymphoid necrosis was present in 3 monkeys that died after day 18. Other microscopic lesions included myocardial degeneration, lymphoid and reticuloendothelial cell hyperplasia and lymphoid depletion. Most of the histopathologic lesions described in human autopsy material were reproduced; however, the necrosis in the skin and oral mucosa, mucosa of the gastrointestinal tract and the adrenal cortex have not been described in man. Despite these apparent discrepancies the results of this investigation indicate that the rhesus monkey is a good experimental model for the study of Bolivian hemorrhagic fever infection. PMID- 4202334 TI - Kinetics of multinucleate giant cell formation and their modification by various agents in foreign body reactions. AB - Foreign body multinucleate giant cells were produced by the implantation of a strip of Melenex in the subcutaneous tissues of mice. The implants were removed at various intervals, and the proportion of multinucleate giant cells as well as the number of nuclei they contained were counted and statistically assessed. The greatest proportion of giant cells was reached 4 weeks after implantation, when 25% of the attached cells were multinucleated. The mean nuclear content however was greatest approximately 2 weeks after implantation and rapidly fell over the ensuing weeks. The fusion potential however, remained almost unaltered for the remainder of the experimental period. Transplantation of 7-day Melenex implants from normal donors into lethally irradiated recipients demonstrated that the halflife of the giant cells is only a few days. Treatment with carrageenin, species-specific antisera, actinomycin D and cortisone inhibited, while puromycin enhanced, multinucleate cell formation. Calcium gluconate, EDTA and irradiation had no significant effect. The possible interpretation of some of these findings is discussed. PMID- 4202336 TI - Mechanism of hyperalimentation in the suppression of upper gastrointestinal secretions. PMID- 4202337 TI - Congenital duodenal atresia. PMID- 4202338 TI - [A case of angina pectoris. Electrocardiographic and mechanographic study]. PMID- 4202340 TI - Screening and isolation of penicillinase inhibitor, KA-107. AB - It is known that penicillin resistance of bacteria is mainly caused by the inactivation of penicillin by penicillinase derived from such strains. We have developed a screening procedure for penicillinase inhibitors. Several microorganisms were found to produce such inhibitors, and from the culture filtrate of Streptomyces gedanensis ATCC 4880 a penicillinase inhibitor, named KA 107, was isolated. The characteristics of this inhibitor were revealed by an in vitro test by using penicillinase derived from penicillin resistant Staphylococcus aureus, FS-1277. When KA-107 was used in combination with penicillin-G, ampicillin, d- or l-phenethicillin, the growth inhibitory activity of these penicillins was maintained. PMID- 4202339 TI - Protein synthesis in Mycobacterium tuberculosis H37Rv and the effect of streptomycin in streptomycin-susceptible and -resistant strains. AB - An efficient in vitro amino acid-incorporating system from Mycobacterium tuberculosis H37Rv was standardized. Ribonucleic acid (RNA) isolated from phage infected M. smegmatis cells served as natural messenger RNA and directed the incorporation of (14)C-amino acids into protein. The effects of various antitubercular drugs and "known inhibitors" of protein synthesis on amino acid incorporation were studied. Antibiotics like chloramphenicol and tetracycline inhibited mycobacterial protein synthesis, though they failed to prevent the growth of the organism. This failure was shown to be due to the impermeability of mycobacteria to these drugs by use of "membrane-active" agents along with the antibiotics in growth inhibition studies. Several independent streptomycin resistant mutants of M. tuberculosis H37Rv were isolated. Streptomycin inhibited the incorporation of (14)C-amino acids into proteins by whole cells of a streptomycin-susceptible strain by more than 90%, whereas very little or no inhibition was observed in either high-level or low-level streptomycin-resistant strains. In vitro, streptomycin was an effective inhibitor of susceptible strains, whereas in streptomycin-resistant strains the concentration of streptomycin at which half-maximal inhibition was produced varied according to the resistance of whole cells, and there was a correlation between the two. In one low-level streptomycin-resistant mutant, the in vitro amino acid incorporating system was as sensitive to various concentrations of streptomycin as the parental type, and a possible involvement of a membrane site in the development of low-level resistance was indicated. Streptomycin susceptibility and high-level resistance were shown to be ribosomal in nature. PMID- 4202343 TI - In vitro activity of cephalothin and three penicillins against Escherichia coli and Proteus species. AB - The susceptibility of clinical isolates of Escherichia coli (67) and Proteus species (58) to cephalothin, ampicillin, benzyl penicillin, and phenoxymethyl penicillin was determined in vitro by using broth dilution and disk diffusion tests. The data were correlated by using a four-category scheme for interpreting minimal inhibitory concentrations (groups 1 to 4) as recommended by a subcommittee of an international collaborative study of susceptibility testing. With cephalothin and ampicillin, groups 1 (susceptible) and 2 (moderately susceptible) were susceptible by the disk test, and with benzyl penicillin, similar results were observed when the interpretive zone standards were changed. Strains categorized as group 4 (very resistant) were resistant by the disk method, but group 3 (moderately resistant) strains were not adequately distinguished by disk testing. Group 3 susceptibility to benzyl and phenoxymethyl penicillins can be predicted by extrapolating results from tests with ampicillin disks. PMID- 4202342 TI - Studies on the susceptibility of 150 consecutive clinical isolates of Pseudomonas aeruginosa to tobramycin, gentamicin, colistin, carbenicillin, and five other antimicrobials. AB - The in vitro susceptibilities of 150 clinical isolates of Pseudomonas aeruginosa to the aminoglycoside tobramycin and eight other antimicrobials were evaluated. The Food and Drug Administration standardized disk diffusion method showed that tobramycin inhibited 100% of the 150 isolates with gentamicin inhibiting only 90.7%. The difference between colistin (97.3%) and tobramycin was less marked. Carbenicillin (87.3%) was found to be slightly less active than gentamicin. Only a small percentage of the isolates were inhibited by the other drugs used. By using a minimal inhibitory concentration of 4 mug/ml in brain heart infusion broth as the level of susceptibility, it was found that only three of the isolates showed resistance to tobramycin, whereas 20 of the isolates were resistant to gentamicin. Approximately half of the isolates were inhibited by 0.5 mug/ml or less of tobramycin, whereas 1.5 mug of gentamicin per ml was required to inhibit 50% of susceptible strains. PMID- 4202341 TI - Additional antibiotic inhibitors of peptidoglycan synthesis. AB - Diumycin, janiemycin, nisin, and subtilin inhibited peptidoglycan synthesis catalyzed by particulate enzyme systems from Bacillus stearothermophilus and Escherichia coli. All of these, except for nisin, also induced accumulation of the lipid intermediate in peptidoglycan synthesis. Concentrations required for 50% inhibition of peptidoglycan synthesis were less than 0.1 mug/ml for diumycin and in the range of 10 to 100 mug/ml for janiemycin, nisin, and subtilin in both organisms. The discrepancy between the extremely low concentration of diumycin required to inhibit the in vitro system from E. coli and the much higher concentration required to inhibit growth of the organism is noteworthy. PMID- 4202344 TI - Lipid composition of gram-negative bacteria, sensitive and resistant to streptomycin. AB - Analyses of streptomycin-sensitive and -resistant gram-negative bacteria show that, contrary to previous reports, the development of antibiotic resistance is not accompanied by changes in membrane lipid or fatty acid composition. PMID- 4202345 TI - Rearing infant rhesus together. PMID- 4202347 TI - The in vitro inhibition of growth of intracellular Listeria monocytogenes by lymphocyte products. PMID- 4202346 TI - International symposium on gonorrhea. PMID- 4202348 TI - The occurrence of 2-hydroxybutyric acid in urine from patients with lactic acidosis. PMID- 4202349 TI - Serum alpha 2-macroglobulin levels in normal Chinese. PMID- 4202350 TI - [The prevalence of serum alpha 1-antitrypsin deficiency in Finland]. PMID- 4202351 TI - [The morbidity of tuberculosis among Finnish pathologists]. PMID- 4202352 TI - Generation of chemotactic activity by immune complexes carrying clustered or nonclustered C42 sites. PMID- 4202353 TI - Immunoglobulins in the intestinal content of the human fetus with special reference to IgA. PMID- 4202354 TI - Isolation of F(c)5mu and Fabmu fragments of human IgM. PMID- 4202355 TI - Effects of nalidixic acid, chloramphenicol, cycloheximide, and anisomycin on structure and development of plastids and mitochondria in greening Euglena gracilis. PMID- 4202356 TI - Immunochemical quantitation of enzymes in human diploid cell line WI-38. PMID- 4202357 TI - 3H-colcicine binding. Failure to detect any binding to soluble proteins from various lower organisms. PMID- 4202358 TI - A cycloheximide-resistant mutant of Tetrahymena pyriformis. PMID- 4202359 TI - Antibody-mediated internalization of B lymphocyte surface membrane immunoglobulin. PMID- 4202361 TI - Effect of inhibitors of RNA and protein synthesis on the aldosterone Na+ transport response in toad bladder. PMID- 4202360 TI - Effects of epididymal maturation, zinc (II) and copper (II) on the reactive sulfhydryl content of structural elements in rat spermatozoa. PMID- 4202362 TI - The peritoneal fluid cytology of the adult female Rhesus monkey. PMID- 4202364 TI - Studies on carrageenan and large-bowel ulceration in mammals. PMID- 4202363 TI - Aflatoxin production in some varieties of soybeans (Glycine max L.). PMID- 4202365 TI - Intestinal effects of carrageenans in the rhesus monkey (Macaca mulatta). PMID- 4202366 TI - Excretion and metabolism of orally administered aflatoxin B1 by rhesus monkeys. PMID- 4202367 TI - Panendoscopy in the early diagnosis of acute upper gastrointestinal bleeding. PMID- 4202369 TI - Further evidence of the inhabitation in a marginal population. PMID- 4202368 TI - Total parenteral nutrition at home for 23 months, without complication, and with good rehabilitation. A study of technical and metabolic features. PMID- 4202370 TI - Chromatin fibril size in salivary gland chromosomes of Drosophila melanogaster. PMID- 4202371 TI - Core fibrils in early mitotic prophase chromosomes of Drosophila melanogaster. PMID- 4202372 TI - Mating behaviour and chaete number in Drosophila melanogaster. PMID- 4202373 TI - Polymorphism at two esterase loci in Drosophila melanogaster from northern Greece. PMID- 4202374 TI - Response of puffing pattern to in vivo treatments with organomercurials in Drosophila melanogaster. PMID- 4202375 TI - Degradation of immunoglobulins by lysosomal enzymes of tumors. I. Demonstration of the phenomenon using mouse tumors. PMID- 4202376 TI - Heat-polymerization of human immunoglobulin G. PMID- 4202377 TI - Heterogeneity of the carcinoembryonic antigen. PMID- 4202378 TI - Different susceptibility of subclasses of rat IgG2 to tryptic digestion. PMID- 4202380 TI - Nutritional status of refugees from Bangla Desh. PMID- 4202379 TI - Phototherapy in Rh incompatibility hyperbilirubinaemia. PMID- 4202381 TI - Quantitative model for the effects of stimulus frequency upon synchronization of auditory nerve discharges. PMID- 4202382 TI - Letter: Precedence effects and auditory cells with long characteristic delays. PMID- 4202383 TI - Letter: Total synthesis and pharmacological activities of N-substituted 3,14 dihydroxymorphinans. PMID- 4202384 TI - [Intracranial calcifications in the course of phacomatoses]. PMID- 4202385 TI - [Ossifying meningoencephalopathy]. PMID- 4202388 TI - New drugs and research: glybenclamide (Euglucon). PMID- 4202386 TI - Behavioral regulation of gravity: schedule effects under escape-avoidance procedures. AB - Squirrel monkeys were restrained in a centrifuge capsule and trained to escape and avoid increases in artificial gravity. During escape-avoidance, lever responses reduced centrifugally simulated gravity or postponed scheduled increases. The effect of variation in the interval of postponement (equal to the duration of decrease produced by escape responses) was studied under a multiple schedule of four components. Three components were gravity escape-avoidance with postponement times of 20, 40, and 60 sec. The fourth component was extinction. Each component was associated with a different auditory stimulus. Rate of responding decreased with increasing postponement time and higher mean g-levels occurred at shorter intervals of postponement. Effects of the schedule parameter on response rate and mean g-level were similar to effects of the schedule on free operant avoidance and on titration behavior maintained by shock. PMID- 4202387 TI - Experience with glibenclamide. PMID- 4202389 TI - Appropriate placement of the chronically ill and aged. A successful approach by evaluation. PMID- 4202390 TI - Autoimmune hemolytic anemia due to levodopa therapy. PMID- 4202391 TI - Present knowledge of the relationship of nutrition to brain development and behavior. PMID- 4202392 TI - [Orthodontics in the USA]. PMID- 4202393 TI - Open and closed treatment of burns with povidone-iodine. PMID- 4202394 TI - [Immunological behavior of patients with malignant blood diseases]. PMID- 4202395 TI - [Circulating antienteral antibodies in chronic enteropathies]. PMID- 4202397 TI - [Relationship between the diameter of the inhibition zone and the concentration of antibiotics (dose-effect-function)]. PMID- 4202398 TI - [Hypothesis of a higher natural resistance against Brucellosis in East African Shorthorn Zebu (Bos indicus)]. PMID- 4202396 TI - [Immunoglobulin content in healthy mature and premature newborn infants]. PMID- 4202399 TI - Snythesis of analogs of the thyrotropin releasing hormone (TRH) and bioassays for TRH- and TRH-inhibiting activities. PMID- 4202400 TI - Congenital cardiac diverticulum. PMID- 4202401 TI - Effects of gram negative endotoxemia on myocardial contractility in the awake primate. PMID- 4202402 TI - Pathologic changes in baboon lung allografts. Comparison of two immunosuppression regimes. PMID- 4202403 TI - Intraluminal diverticulum of the duodenum. PMID- 4202404 TI - The threshold and neuropathology of cerebral "anoxic-ischemic" cell change. PMID- 4202405 TI - Reversibility of ischemic brain damage. PMID- 4202406 TI - Two classes of dysergic brain abnormality and their conditions of occurrence. PMID- 4202407 TI - Experimental investigations on interactions between gentamicin and betamethasone dipropionate. PMID- 4202408 TI - Antigenic properties of rat brain proteins fraction. PMID- 4202409 TI - Congenital membranous stenosis of the midesophagus. A case report and literature survey. PMID- 4202410 TI - A specific increase in cardiovascular reactivity related to sodium retention in DOCA-salt-treated rats. PMID- 4202411 TI - [Chronic interstitial nephritis after long-term use of phenacetin-containing anti asthma drugs (autor's transl)]. PMID- 4202412 TI - [Endocarditis caused by diphtheroids and lactobacilli (author's transl)]. PMID- 4202413 TI - [Biosynthesis and absorption of the cerebrospinal fluid]. PMID- 4202414 TI - The detection and localization of carbonic anhydrase in the rabbit cornea. PMID- 4202415 TI - Letter: Fractionation of the soluble proteins of chick lens on Sephadex column. PMID- 4202416 TI - Nucleus of the accessory optic tract. Light and electron microscopic study in normal monkeys and after eye enucleation. PMID- 4202417 TI - Loss of visual control of the forelimb after interruption of cortical pathways. PMID- 4202418 TI - Injury-induced long-first-interval bursts in cortical neurons. PMID- 4202419 TI - Antiglobulins and cryoglobulins in rabbits producing homogeneous streptococcal antibodies. PMID- 4202420 TI - Experimental cryoglobulinaemia. Production and properties of streptococcus induced rabbit cryoglobulins. PMID- 4202422 TI - Modification of the enzymic activity of trypsin by intramolecular cross-links. PMID- 4202421 TI - The serological response of the chicken to a protein antigen in multiple emulsion oil adjuvant. PMID- 4202423 TI - Giant cell arteritis--the need for prolonged treatment. PMID- 4202424 TI - Ultrastructure of selected bacteria isolated from dental plaque as revealed by freeze-etching. PMID- 4202425 TI - Electron microscopic study of the effect of water jet lavage devices on dental plaque. PMID- 4202426 TI - Fluoride concentration in root surfaces and alveolar bone of fluoride-immersed monkey incisors three weeks after replantation. PMID- 4202427 TI - Proceedings: Asynchronous pulsatile luteinizing hormone and follicle-stimulating hormone responses during luteinizing hormone-follicle-stimulating hormone releasing hormone and thyroid-stimulating hormone releasing hormone infusions. PMID- 4202428 TI - Proceedings: Distribution of radioimmunoassayable gastrin, secretin, pancreozymin and enteroglucagon in rat, dog, and baboon gut. PMID- 4202429 TI - Proceedings: Prolactin release in the ewe induced by a synthetic tripeptide. PMID- 4202430 TI - [Preventive effect of garlic extract against influenza]. PMID- 4202431 TI - Effects of psychoactive drugs on nonverbal communication and group social behavior of monkeys. PMID- 4202433 TI - Activity of magnocellular neuroendocrine cells in the hypothalamus of unanaesthetized monkeys. II. Osmosensitivity of functional cell types in the supraoptic nucleus and the internuclear zone. AB - 1. We studied magnocellular neuroendocrine cells and non-neuroendocrine cells in the supraoptic nucleus (n.s.o.) and internuclear zone (i.n.z.) in the hypothalamus of unanaesthetized, chronically prepared monkeys. After antidromic identification, functional cell typing and sensory testing we injected solutions of varying tonicity into an implanted carotid cannula to determine osmosensitivity.2. On the basis of the anatomical location of the cells, the pattern of discharge in response to osmotic stimuli, the effect of posterior pituitary gland stimulation and the response to non-noxious arousing sensory stimuli, we divided the 101 osmosensitive cells studied into two major groups: eighty-nine (88%) ;specific' biphasic osmosensitive magnocellular neuroendocrine cells and twelve (12%) ;non-specific' monophasic osmosensitive non-neuroendocrine cells.3. ;Non-specific' non-neuroendocrine osmosensitive cells included nine (9%) cells lying in the internuclear zone (i.n.z.) and showing monophasic exictatory or inhibitory responses to both osmotic and to mildly arousing sensory stimuli. Three (3%) ;high-frequency burster' (h.f.b.) osmosensitive cells were located in the n.s.o.-t.o. (supraoptic nucleus-optic tract) junction, showed accelerated discharge to auditory, but not to light or touch stimuli, and were monophasically inhibited by osmotic stimuli.4. Thirty-three (33%) antidromically ;identified' magnocellular neuroendocrine cells in the n.s.o. and i.n.z. we classify as ;specific' biphasic osmosensitive cells on the basis of the excitatory-inhibitory response to intracarotid hypertonic sodium chloride and the lack of response to non-noxious arousing sensory stimuli. Fifty-six (55%) of the ;non-identified' magnocellular neuroendocrine cells in the n.s.o. and i.n.z. we also found to be ;specific' biphasic osmosensitive cells.5. Magnocellular neuroendocrine cells in n.s.o. and i.n.z. exhibited three functional types, ;silent' (s.), ;continuously active' (c.a.), and ;low frequency burster' (l.f.b.), all of which were osmosensitive with a ;specific' biphasic response. With osmotic loading some of the ;s.' cells tended to shift transiently to ;c.a.' firing, an occasional ;c.a.' cell burst briefly and a few ;l.f.b.' cells increased bursting for a short time (60 sec).6. We conclude that magnocellular neuroendocrine cells in n.s.o. and i.n.z. respond ;specifically' to intracarotid hypertonic sodium chloride with biphasic, excitatory-inhibitory, discharges and do not respond to mildly arousing sensory stimuli. We suggest that, under the conditions of our experiments, the three functional types of magnocellular neuroendocrine cells (s., c.a., l.f.b.), arising from a common primitive neuroendocrine cell, are randomly dispersed in n.s.o. and i.n.z., are each ;specialized' for secretion of a ;specific' neurohypophysial hormone, and are sensitive to ;specific' input connexions. Under this ;specific hormonal state' hypothesis we explain the paradoxical and uniform osmosensitivity of these three different functional cell types on the basis of a suprathreshold osmotic stimulus and a residual ;primitive' osmosensitivity. At present we are unable to say which functional magnocellular neuroendocrine cell types secrete a particular neurohypophysial hormone. PMID- 4202432 TI - Activity of magnocellular neuroendocrine cells in the hypothalamus of unanaesthetized monkeys. I. Functional cell types and their anatomical distribution in the supraoptic nucleus and the internuclear zone. AB - 1. We recorded with tungsten micro-electrodes the spontaneous and evoked activity of single cells in the supraoptic nucleus (n.s.o.) and internuclear zone (i.n.z.) of trained, unanaesthetized monkeys who accepted experimental restraints and pituitary gland stimulation without anxiety.2. Of the 125 hypothalamic neurones analysed, 109 (87%) we classified as magnocellular neuroendocrine cells on the basis of the anatomical location of the cells, the pattern of spontaneous discharge, the effect of pituitary gland stimulation and the response to arousing sensory stimuli.3. Sixteen (13%) of the cells studied under identical conditions we labelled as non-neuroendocrine cells. Located in the i.n.z. and supraoptic nucleus-optic tract junction (n.s.o.-t.o.), these cells responded to arousing sensory stimuli, showed ;continuously active' (i.n.z.) and ;high-frequency burster' (n.s.o.-t.o.) patterns of discharge and were not driven by pituitary stimuli.4. Thirty-seven (30%) of the magnocellular neuroendocrine cells we describe as ;identified' because with pituitary gland stimulation we evoked antidromic potentials, mean latency 8.1 msec and mean conduction velocity 0.8 m/sec, with collision between orthodromic and antidromic potentials. Antidromic excitation of neuroendocrine cells was followed by inhibition of spontaneous discharge of cells for 80-125 msec suggesting the presence of recurrent collaterals in primate neuroendocrine cells. Seventy-two (57%) of the magnocellular neuroendocrine cells we designated as ;non-identified' because of lack of response, failure of collision or non-tested to pituitary gland stimulation. None of these mangocellular neuroendocrine cells, ;identified' or ;non-identified', responded to non-noxious arousing sensory stimuli.5. We find seventy-nine (63%) magnocellular neuroendocrine cells in the supraoptic nucleus (n.s.o.) and thirty (24%) magnocellular neuroendocrine cells in the internuclear zone (i.n.z.) with three basic patterns of spontaneous activity: ;silent' cells (s., four cells, 3%); ;low-frequency burster' cells (l.f.b., twenty-six cells, 21%); and ;continuously active' cells (c.a., seventy-nine cells, 63%).6. Twenty six (21%) l.f.b. magnocellular neuroendocrine cells exhibited regular, repetitive, periodic firing patterns with a cycle of 17 sec, involving 5 sec of discharge at 5 spikes/sec and 12 sec of silence. The 26 spikes/burst showed no consistent pattern of serial interspike interval distribution. The burst pattern of discharge was interrupted by intracarotid osmotic stimuli but not by mildly arousing sensory stimuli or sleep-waking behaviour. Mean antidromic latencies of 7.98 msec and the anatomical distributions were the similarities exhibited by the l.f.b. and the c.a. cells.7. We conclude that the three functional types, s., c.a. and l.f.b., of the magnocellular neuroendocrine cells, are randomly distributed in the supraoptic nucleus (n.s.o.) and in the internuclear zone (i.n.z.) with each type receiving ;specific' input connexions. We suggest that these three characteristic firing patterns of magnocellular neuroendocrine cells may be related to the ;cellular' secretion of ;specific' neurohypophysial hormones and neurophysins. PMID- 4202434 TI - Intravascular coagulation--a source of possible error in carbon-clearance determinations. PMID- 4202435 TI - One stage cardiac denervation without transplantation. PMID- 4202436 TI - [Biological characteristics and pathogenicity of Yersinia enterocolitica. 2. Experimental infection in monkeys and pathological observation]. PMID- 4202437 TI - [An application of universal determination of body fluid protein-concentration. II. 131-I-BSP binding human serum proteins (author's transl)]. PMID- 4202438 TI - [Studies on the properties of human fibrinogen using immunodiffusion method (author's transl)]. PMID- 4202439 TI - [Biological characteristics of Pseudomonas aeruginosa (author's transl)]. PMID- 4202440 TI - The implications of hyperammonemia in rare and common disorders, including migraine. PMID- 4202441 TI - Prevention of pacemaker infections. PMID- 4202442 TI - Skeletal scintigraphy. I. PMID- 4202443 TI - [Treatment of elderly patients with an effective anxiolytic drug combination]. PMID- 4202444 TI - Proceedings: Hughlings Jackson Lecture. Cortical localization and "sensori motor processes" at the "middle level" in primates. PMID- 4202445 TI - Electron and x-ray beam characteristics of the linac LMR-13. PMID- 4202446 TI - Effect of preoperative radiotherapy on the growth of human renal carcinoma tissue in vitro. PMID- 4202447 TI - [Lack of Australia antigen in patients with mitochondrial antibodies in their serum]. PMID- 4202448 TI - [Criteria for the effect of photic rhythms on biological clock phases]. PMID- 4202449 TI - Maximal cardiac output during exercise in patients with coronary artery disease. PMID- 4202450 TI - Transferrin concentration in human amniotic fluid. PMID- 4202451 TI - Postmortem formation of giant endothelial vacuoles in Schlemm's canal of the monkey. PMID- 4202452 TI - Ultrastructural studies of the blood-aqueous barrier. 2. The barrier to horseradish peroxidase in primates. PMID- 4202453 TI - Assessing the costs and benefits of anti-malaria programs: the Indian experience. PMID- 4202455 TI - The Ausria test: critical evaluation of sensitivity and specificity. PMID- 4202454 TI - The role of red cell energy metabolism in the generation of irreversibly sickled cells in vitro. PMID- 4202456 TI - Polygraphic studies of the effect of nitroglycerin in patients with ischaemic heart disease. PMID- 4202458 TI - Correspondence: The quantitative determination of immunoglobulins by radial diffusion techniques. PMID- 4202457 TI - Immune response to a syngeneic rat tumour: evolution of serum cytotoxicity and blockade. AB - The development of serum factors by Wistar rats during the growth of a syngeneic squamous cell carcinoma has been investigated to clarify the nature of the local lymphocyte anergy reported previously in this system. Sera from tumour bearing animals were tested for cytotoxicity against tumour cells by in vitro microassay, and their ability to inhibit cell mediated cytotoxicity was also studied. Serum cytotoxicity was first detected after 2 weeks of tumour growth, reaching a peak at 4 weeks and then declining. Inhibitory activity was found only in the sera of animals with advanced tumours. Anti-tumour antibody either in the sera or bound to tumour cells was not detected by immunofluorescence techniques. No evidence of general immunological debilitation was found, the animals showing normal immune responses to sheep erythrocytes and killed Brucella abortus organisms throughout tumour growth. Serum inhibitory factors may be responsible for the decline in anti-tumour immunoreactivity and the local lymphocyte anergy observed in tumour bearing hosts. PMID- 4202459 TI - Waldenstrom's macroglobulinemia presenting as a pulmonary mass. PMID- 4202460 TI - Hydroxyproline index in malnutrition. PMID- 4202461 TI - Significance of serologic abnormalities in lepromatous leprosy. PMID- 4202462 TI - Ossifying lipofibroma of the median nerve. PMID- 4202463 TI - Immunological aspects of schistosomiasis. A review. PMID- 4202464 TI - Further studies on Hepatitis Associated Antigen in acute hepatitis in Upper Egypt. PMID- 4202465 TI - [Immunological aspects of human and experimental schistosomiasis]. PMID- 4202466 TI - [Immunological diagnosis of amebiasis. (Comparison of different technics apropos of 424 cases)]. PMID- 4202467 TI - [False reactions in the immunological diagnosis of echinococcosis]. PMID- 4202468 TI - A preliminary report on the differentiation of bloods of avian species. PMID- 4202469 TI - Editorial: Steroid induced peptic ulcer. PMID- 4202470 TI - Studies on sperm capacitation. I. The relationship between a guinea-pig sperm coating antigen and a sperm capacitation phenomenon. PMID- 4202471 TI - Proceedings: The use of drugs to elucidate the mechanism of luteolysis in the pseudopregnant rat. PMID- 4202472 TI - Variations in glomerular ultrastructure in rat kidneys fixed by perfusion. PMID- 4202473 TI - Cancer of the gastrointestinal tract. II. Esophagus: treatment--localized and advanced. PMID- 4202474 TI - Cancer of the gastrointestinal tract. II. Esophagus: Treatment--localized and advanced. Value of radiation therapy. PMID- 4202475 TI - Cancer of the gastrointestinal tract. II. Esophagus: Treatment--localized and advanced. Innovations in radiation therapy. PMID- 4202477 TI - [Concentrated preparation of Streptococcus lactis bacteriophage]. PMID- 4202476 TI - [Occurrence in normal human serum of antibodies neutralizing toxic properties of rickettsia typhi]. PMID- 4202478 TI - Problems of mutation detection in independently evolving laboratory strains. PMID- 4202479 TI - Hypothesis of post-recombination resynthesis of gene copies. PMID- 4202480 TI - Antigenic differences between isolates of swine vesicular disease virus and their relationship to Coxsackie B5 virus. PMID- 4202481 TI - Association of alpha-macroglobulins with lymphoid cells. PMID- 4202482 TI - An antenatal diagnosis of spina bifida in the Lewis rat. PMID- 4202483 TI - Suppression of TRH-mediated thyroidal release of 131-I by a synthetic analog. PMID- 4202484 TI - The absorption of amoxycillin. PMID- 4202485 TI - Time for a change? PMID- 4202486 TI - The differential diagnosis of traumatic lesions of the occipito-atlanto-axial segment. PMID- 4202487 TI - Treatment of epilepsy with clonazepam (Ro 5-4023). PMID- 4202488 TI - Malignant degeneration of a peripheral neurofibroma with pitfalls in angiographic diagnosis. PMID- 4202489 TI - [Optimal conditions for performing the absorption-elution reaction for the detection of RhO(D) antigen in blood stains]. PMID- 4202491 TI - Raising leucocyte alloantisera in limited populations of sub-human primates. PMID- 4202490 TI - Studies on recombination within the mouse H-2 complex. I. Three recombinants which position the Ss locus within the complex. PMID- 4202492 TI - [Effect of raubasine and dihydroergocristine on arteriosclerotic and hypertensive cerebral diseases]. PMID- 4202493 TI - A comparison of vaginal tampon tests used in the eradication of brucellosis. PMID- 4202494 TI - Brucellosis in bulls. PMID- 4202495 TI - Metabolism of 6-chloro-9 beta, 10 alpha-pregna-1,4,6-triene-3,20-dione in rat, rabbit, monkey and man. PMID- 4202496 TI - [Reaction of the ovary to injury]. PMID- 4202497 TI - Sluice flow in placenta: maternal vascular pressure effects on fetal circulation. PMID- 4202498 TI - Serum IgG, IgM, and IgA levels in ankylosing spondylitis. PMID- 4202499 TI - [Isolation of the placental proteins PP2 and its identification as ferritin (author's transl)]. PMID- 4202500 TI - Studies on the transcobalamins. PMID- 4202501 TI - Test for carcinogenicity of food additives and chemotherapeutic agents by the pulmonary tumor response in strain A mice. PMID- 4202502 TI - Enhanced plasma thyrotrophin response to thyrotrophin-releasing hormone following oestradiol administration in man. PMID- 4202503 TI - Serum thyrotrophin response to thyrotrophin-releasing hormone in normal children and in patients with short stature and various endocrine or genetic diseases. PMID- 4202504 TI - The effect of thyrotrophin-releasing hormone on plasma prolactin and thyrotrophin levels in primary hypothyroidism. PMID- 4202505 TI - A specific effect of mimosine on melanoma cells. PMID- 4202506 TI - Genetic marker systems in arctic populations VII. Genetic variation in serum lipoproteins in Icelanders. PMID- 4202507 TI - Phenotypic bioassay of five tribes of Orissa, India. PMID- 4202508 TI - Ag (x,y,a1,z,t) antigens in Australian and New Guinea populations. PMID- 4202510 TI - Characteristics of Herpesvirus saimiri-induced lymphoma cells in tissue culture. PMID- 4202512 TI - Electron-microscopic observations on the macronuclear development of Stylonychia mytilus and Tetrahymena pyriformis (Ciliophora-Protozoa). PMID- 4202511 TI - Further experiments on the role of the nucleolus in the transfer of RNA from nucleus to cytoplasm. PMID- 4202509 TI - Studies on the cultivation of mammalian cell lines in a serum-free, chemically defined medium. PMID- 4202513 TI - Contrasting incidence of Rocky Mountain spotted fever in ticks infesting wild birds in eastern U.S. Piedmont and coastal areas, with notes on the ecology of these ticks. PMID- 4202514 TI - Tuberculous cervical lymphadenitis (scrofula). PMID- 4202515 TI - Activity and some properties of an acid proteinase from normal and Plasmodium berghei-infected red cells. PMID- 4202516 TI - Antigenicity of fractions of a somatic antigen of Trypanosoma cruzi. PMID- 4202517 TI - Hematological changes in white-tailed deer fawns, Odocoileus virgianianus, infested with Theileria-infected lone star ticks. PMID- 4202518 TI - Development of Sarcocystis fusiformis in calves infected with sporocysts from dogs. PMID- 4202519 TI - Asymptomatic gonorrhea in men. Diagnosis, natural course, prevalence and significance. PMID- 4202520 TI - Fatty liver, alcoholic hepatitis and cirrhosis produced by alcohol in primates. PMID- 4202521 TI - The new national health spending policy. PMID- 4202522 TI - Meningococcal pericarditis without meningitis presenting as tamponade. PMID- 4202523 TI - Letter: Tumor-associated antigen in human meningioma. PMID- 4202524 TI - [Tobramycin: antibacterial activity compared to gentamicin. Pharmacologic and therapeutic study in the child]. PMID- 4202525 TI - [Jejunostomy for feeding after total gastrectomy]. PMID- 4202526 TI - Interaction of H+ and Ca++ in the regulation of local pial vascular resistance. PMID- 4202527 TI - The structure of the chicken egg shell and shell membranes as studied with the scanning electron microscope and energy dispersive x-ray microanalysis. PMID- 4202528 TI - Parameters of infection in chicks exposed to Marek's disease by two different methods. PMID- 4202529 TI - The use of the chromium complex of ethylenediaminetetra-acetic acid for studies of digestion in sheep. PMID- 4202530 TI - Some effects of diet with oral contraceptives on carbohydrate:lipid metabolism in the baboon. PMID- 4202531 TI - Biochemical characteristics of different forms of protein-energy malnutrition in rats. PMID- 4202532 TI - Plasma amino acid concentrations and ratios in different forms of protein-energy malnutrition in rats. PMID- 4202533 TI - Abnormal behavior in non-isolate-reared rhesus monkeys. PMID- 4202534 TI - 3 methoxytyramine: a possible endogenous toxin of psychosis? PMID- 4202535 TI - [Determination of carbaryl in apples]. PMID- 4202536 TI - Folate studies in underprivileged children with epilepsy. PMID- 4202537 TI - [Parenteral nutrition in stomatology]. PMID- 4202538 TI - Pseudomonas aeruginosa cervical diskitis with chondro-osteomyelitis in an intravenous drug abuser. PMID- 4202539 TI - Summary of recent abstracts. IV. Trypanosomiasis. PMID- 4202540 TI - A case of generalised avian tuberculosis in a horse. PMID- 4202541 TI - The immuno-diffusion method for the identification of cattle vaccinated with Brucella abortus strain 45-20. PMID- 4202542 TI - [Isolation of gonococci from the rectal secretion in women with gonorrheal disease of the urogenital organs]. PMID- 4202543 TI - Determination of lidocaine in blood and tissues. PMID- 4202544 TI - Betamethasone 17-valerate by aerosol in childhood asthma. PMID- 4202545 TI - Thermal insulation in malnourished Jamaican children. PMID- 4202546 TI - In vitro stimulation of lecithin synthesis in rat liver mitochondria and microsomes after treatment with phospholipase C. PMID- 4202547 TI - A manganese-stimulated endonuclease from Bacillus subtilis. PMID- 4202548 TI - Insulin degradation. X. Identification of insulin degrading activity of rat liver plasma membrane as glutathione-insulin transhydrogenase. PMID- 4202549 TI - Temperature dependent permeability changes of Bacillus subtilis and incorporation of nucleotides into DNA. PMID- 4202550 TI - Involvement of the biosynthetic pathway of purine nucleotides in the repression of bacterial sporulation. PMID- 4202551 TI - A new approach to the characterization of the B and A forms of DNA by I.R. spectroscopy. PMID- 4202552 TI - Differences in susceptibility to phospholipase C of free and membrane-bound phospholipids of Mycoplasma hominis. PMID- 4202553 TI - Immunologic studies on nucleic acids and their components. I. An analysis of the specificity of anti-deoxyadenylate antibodies by a membrane-binding technique. PMID- 4202554 TI - The effect of fluoride and molybdate on caries activity in monkeys (Macaca fascicularis). PMID- 4202555 TI - The administration's program for the aged. PMID- 4202556 TI - Changing life styles in housing for the aged. PMID- 4202557 TI - Dietary management of renal failure in infants and children. Principles of nutritional therapy and some representative diets. PMID- 4202559 TI - [Diabetic ketotic coma]. PMID- 4202558 TI - [The use of Clinicult in the laboratory diagnosis of gonorrhea]. PMID- 4202560 TI - The effects of low concentrations of actinomycin D upon nucleic acid synthesis in different cell types. PMID- 4202561 TI - [Change in the polarization fluorescence of cells undergoing damage]. PMID- 4202562 TI - Effects of male paragonial gland secretion on sexual receptivity and courtship behaviour of female Drosophila melanogaster. PMID- 4202563 TI - Structure of cephalic abnormalities in Drosophila melanogaster (Diptera: Drosophilidae). PMID- 4202564 TI - Isolation and characterization of symbiotes from the Rocky Mountain wood tick, Dermacentor andersoni. PMID- 4202565 TI - Reproduction in two species of spider monkeys, Ateles fusciceps and Ateles geoffroyi. PMID- 4202566 TI - Human placental lactogen (HPL) levels in abnormal pregnancies. PMID- 4202567 TI - Rho (d) immune globulin (human). PMID- 4202569 TI - Treatment of pterygia with and without thiotepa. PMID- 4202568 TI - Scanning electron microscopy of the primate retina. PMID- 4202570 TI - [Buffering of the animal feed ration with montmorillonite (bentonite) in ruminants under experimental conditions]. PMID- 4202571 TI - [Cultivation of virus of infectious bovine rhinotracheitis--infectious pustular vulvovaginitis of cattle in a stable line of calf kidney epithelium]. PMID- 4202572 TI - [Use of imprint preparations in the immunofluorescent diagnosis of viral gastroenteritis in pigs]. PMID- 4202573 TI - [Effect of transportation as a stress factor on the blood picture of the German shepherd-dog]. PMID- 4202574 TI - [Hematological changes of the bone marrow in model, non-contact burns in rats]. PMID- 4202575 TI - [Changes in the enzyme supply of absorption cells of the small intestine in guinea pigs after whole body irradiation by Co60]. PMID- 4202576 TI - [Significance of laterally separated isotope clearance in the clinical picture]. PMID- 4202577 TI - Exercise tolerance and physical training of non-selected patients after myocardial infarction. PMID- 4202578 TI - Phenol oxidase activity in brain tissue. PMID- 4202579 TI - Prostaglandins and cannabis. II. Inhibition of biosynthesis by the naturally occurring cannabinoids. PMID- 4202580 TI - Enzyme kinetics in relation to enzyme inhibitors. PMID- 4202581 TI - Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. PMID- 4202582 TI - The metabolism of glyceryl trinitrate by liver and blood from different species. PMID- 4202583 TI - In vitro inhibition of the biosynthesis of a prostaglandin by gold and silver. PMID- 4202584 TI - [The chromosomic boundaries of hominization]. PMID- 4202585 TI - [Histogenesis of Hassall's corpuscules in mice in experimental tuberculosis]. PMID- 4202586 TI - [Role of auditory autoperception in choice orientation of chicks without maternal experience]. PMID- 4202587 TI - [Lipolytic effect of porcine somatotropic hormone on rabbit adipocytes]. PMID- 4202588 TI - [Sensitivity of the preoptic area of the hypothalamus of the male rat to androgens]. PMID- 4202589 TI - [In vitro cell cultures of the fresh water planarian, Polycelis tenuis (Iijima)]. PMID- 4202590 TI - [Ovarian autodifferentiation in the oligochaetous annelid, Eisenia fetida f. typica sav., demonstrated by means of organ culture]. PMID- 4202591 TI - [Involution with age of the ability to regenerate in actinomycin D in the planarian, Polycelis tenuis-nigra]. PMID- 4202592 TI - [Influence of experimental metamorphosis on plasma and erythrocyte lactic dehydrogenase isoenzymes in Ambystoma mexicanum Shaw]. PMID- 4202593 TI - [Allophenic intergeneric chimera between Pleurodeles waltlii Michah and Ambystoma mexicanum Shaw. (Amphibia, Urodeles). Demonstration of tegument chimerism]. PMID- 4202594 TI - [Effect of an adrenergic beta receptor inhibitor (propranolol) on arterial hypertension induced by carotid sinus denervation and vagotomy in dogs]. PMID- 4202596 TI - [Interactions between colicins and various constituents of the bacteria surface]. PMID- 4202595 TI - [Pathophysiologic and nutritional effects of amino-4-trichloro-3,5,6-picolinic acid (picloram) in rats]. PMID- 4202597 TI - [Isolation of a feline sarcomatogenous virus from a spontaneous fibrosarcoma in cats: study of its sarcomatogenous power in vivo]. PMID- 4202598 TI - [The vector role of Bulinus of the forskalii group in schistosomiasis]. PMID- 4202599 TI - [Effect of interferon on RNA, protein and polyribosome synthesis in murine L 1210 leukemia cells]. PMID- 4202600 TI - Polyamines and polyamine-metabolizing enzyme activities in human semen. PMID- 4202601 TI - [The effect of hydantoin and succinimide on vitamin B 6 metabolism]. PMID- 4202603 TI - Competitive growth of Salmonella and Pseudomonads in tetrathionate enrichment broth. PMID- 4202602 TI - Chagas enteropathy. PMID- 4202604 TI - An evaluation of commercially supplied Transgrow and Amies media for the detection of Neisseria gonorrhoeae. PMID- 4202605 TI - Sensitivity of radioimmunoassay for hepatitis B antigen in diagnostic and survey work. PMID- 4202606 TI - Non-specific binding of IgG to antibody-coated red cells. (The 'Matuhasi-Ogata phenomenon'). PMID- 4202607 TI - Contralateral epididymo-orchitis after cryo-injury to the male rabbit gonad. PMID- 4202608 TI - Physiology and pharmacology of local anesthetic agents. PMID- 4202609 TI - Feed sources and conditions conducive to production of aflatoxin, ochratoxin, Fusarium toxins, and zearalenone. PMID- 4202610 TI - Passage of bovine serum albumin from the mother to rabbit blastocysts. I. Passage from the circulation to uterine lumen. PMID- 4202611 TI - Passage of bovine serum albumin from the mother to rabbit blastocysts. II. Passage from uterine lumen to blastocyst fluid. PMID- 4202612 TI - A note on the purification of follicle-stimulating and luteinizing hormones from baboon pituitaries. PMID- 4202613 TI - Eye movements evoked by cerebellar stimulation in the alert monkey. PMID- 4202614 TI - Effects of cooling dentate nucleus on tracking-task performance in monkeys. PMID- 4202615 TI - Effects of cooling interposed nuclei on tracking-task performance in monkeys. PMID- 4202616 TI - Experimental comparison of radioactive agents for studies of the placenta. PMID- 4202617 TI - Cold-sensitive Pseudomonas RNA polymerase. I. Characterization of the host dependent cold-sensitive restriction of phage CB3. AB - Analysis of bacteriophage CB3 infection of Pseudomonas aeruginosa strain PAT2 establishes that phage induced changes in net macromolecular synthesis are absent at nonpermissive phage growth temperatures (32 C). Alterations which are evident in the PAT2 strain at 37 C or in the fully permissive strain, PAO1C, at either warm or cold temperatures do not occur in PAT2 at low temperatures. CB3 DNA synthesis and the degradation of host DNA to approximately 78S components occur at 37 C, but are absent in PAT2 at 20 C. Nevertheless, attachment of phage DNA to host cytoplasmic material occurs under permissive and nonpermissive conditions. This binding of phage DNA at 20 C is identical in nature to phage DNA bound at 37 C. Thus, the conditional cold-sensitive PAT2 host function in the growth of CB3 is expressed subsequent to membrane binding of the infecting genomes but prior to the onset of the initiation of CB3 DNA synthesis, the inhibition of host DNA synthesis, and the transient depression in RNA synthesis which occurs in permissive cells. PMID- 4202619 TI - Antigenic properties of bacteriophage phi 29 structural proteins. AB - Serological methods and electron microscopy were used to study the structural proteins of the small Bacillus subtilis bacteriophage phi29. This virus has a large number of fibers attached at both ends of its prolate head. A complex neck assembly is comprised of 12 symmetrically arranged appendages as the outer component. Head fibers, neck appendages, and the head surface bind anti-phi29 antibodies. Immune sera absorbed with defective lysates of suppressor-sensitive (sus) mutants have been used to determine the genetic control of neck appendages production. Studies on the serum-blocking power of lysates defective in different tail components showed that appendages contain the main serum-blocking protein. This finding suggests an essential role of the neck appendages in phage adsorption or DNA injection. PMID- 4202618 TI - Cold-sensitive Pseudomonas RNA polymerase. II. Cold-promoted restriction of bacteriophage CB3 and the lack of host-dependent bacteriophage-specific RNA transcription. AB - Cold-sensitive restriction of Pseudomonas phage CB3 by Pseudomonas aeruginosa strain PAT2 involves some aspect of CB3 specific RNA synthesis at 20 C. Experiments using chloramphenicol treatment and RNA-DNA hybridization establish that the amount of CB3 RNA present at 20 C is consistent with the known percentage of phage yielder cells at 20 C. Thus, it appears that nonyielder cells of PAT2 synthesize little or no phage-specific mRNA. Burgess technique extracted PAT2 RNA polymerase (RNAP) is cold sensitive when assayed in vitro with CB3 DNA at 20 C. However, it is not cold sensitive when either calf thymus or PAT2 DNA are the templates for transcription. Low ionic strength assay conditions eliminate the cold sensitivity of PAT2 RNAP. The effect of low ionic environments on transcription initiation along with the in vivo and in vitro suppression of cold sensitivity by host rifampin resistance suggests that the inability of CB3 to reproduce in PAT2 at 20 C is a cold-sensitive step in host RNAP initiation. Our modified RNAP extraction procedure for PAT2 and PAO1C also results in the recovery of cold-sensitive PAT2 RNAP with respect to CB3 DNA templates and points to basic enzymological differences between the two hosts. A model is presented for the unusual influence of temperature on the initiation process of both PAT2 and PAO1C on RNAP transcription. PMID- 4202620 TI - [Minimal bactericidal concentration (MBC) of carbenicillin against clinically isolated bacteria]. PMID- 4202621 TI - [Studies of the joint mechanics elucidating the pathogenesis of posttraumatic arthrosis of the ankle joint in man. 3. Functional morphometric analysis of the articular cartilage (author's transl)]. PMID- 4202622 TI - Isolation of skyrin from Hypomyces iactifluorum. PMID- 4202623 TI - The secretion of migration inhibitory factor by intact schistosome egg granulomas maintained in vitro. PMID- 4202624 TI - Development of the auditory cortex of monkeys during prenatal ontogenesis. PMID- 4202625 TI - A comparison of the cardiovascular actions of thalicarpine and its moieties. PMID- 4202626 TI - [Physiological and biological principles of the neutron therapy]. PMID- 4202627 TI - [Pendulum electron irradiation of the pelvic region using a cone with blinds]. PMID- 4202628 TI - [Comparative study of the chromosome constitution of 2 species of macacque]. PMID- 4202629 TI - Mechanism of action of L-asparaginase on the cell cycle and growth in acute lymphoblastic leukemia. PMID- 4202630 TI - The effect of L-asparaginase on DNA and RNA synthesis by lymphoblasts of acute lymphocytic leukemia. PMID- 4202631 TI - Lymphocyte surface markers in lymphoproliferative disorders. PMID- 4202632 TI - Binding of folic acid to serum proteins. II. The effect of diphenylhydantoin treatment and of various diseases. PMID- 4202634 TI - Blood group and tissue mosaicism in a Natal Indian woman. PMID- 4202633 TI - The prevalence of Australia antigen and antibody in haemophilia. PMID- 4202635 TI - Acquired factor IX deficiency. A report of two cases. PMID- 4202636 TI - Haemoglobin D Punjab in a Cuban family and its interaction with haemoglobin S. PMID- 4202637 TI - Human simulated diving experiments at saturation under oxygen-helium exposures up to 500 meters: electroencephalographic data. PMID- 4202638 TI - Electron microscopic study of endothelium of stored and cryopreserved monkey corneas. PMID- 4202639 TI - Infection control in intravenous therapy. PMID- 4202641 TI - Studies on the life cycle of Phaneropsolus bonnei and Prosthodendrium molenkampi in Thailand. PMID- 4202640 TI - Interference between borreliae and trypanosomes. I. Antigenic analysis, fluorescent antibody and immobilisine studies of Borrelia turicatae and Trypanosoma cruzi. PMID- 4202642 TI - [Effictiveness of treatment of carriers of Corynebacterium diphtheriae in ambulatory care]. PMID- 4202644 TI - Chromosomal proteins of Drosophila embryos. PMID- 4202645 TI - Microheterogeneity of rat liver ferritin: comparison of electrofocusing and chromatographic fractions. PMID- 4202643 TI - Fetal hormones, the brain, and human sex differences: a heuristic, integrative review of the recent literature. PMID- 4202646 TI - [Nature and ontogenetic development of carboanhydrase isoenzymes in human erythrocytes]. PMID- 4202647 TI - The binding affinities of rheumatoid factors interacting with the C gamma 3 homology region of human IgG. PMID- 4202648 TI - Immunological and physicochemical studies of IgA1 (delta) cryogelglobulinaemia. PMID- 4202649 TI - Scoliosis. PMID- 4202650 TI - Proceedings: Factors affecting repair of sublethal injury in frozen or freeze dried bacteria. PMID- 4202651 TI - Proceedings: The preservation of ciliated protozoa at low temperature. PMID- 4202652 TI - Proceedings: Freezing and freeze-drying of Spirulina platensis. PMID- 4202653 TI - [Monoclonal macroglobulinaemia (author's transl)]. PMID- 4202655 TI - Diagnosing thyroid disease by selected laboratory tests. PMID- 4202656 TI - [Environmental pollution by polychlorinated biphenyls]. PMID- 4202654 TI - Lidoflazine: double-blind trial of a new coronary vasodilator in angina pectoris. PMID- 4202657 TI - The effects of temporary protein deprivation on bone width and bone mineral content in rhesus macaques. PMID- 4202658 TI - Degradation of coxsackievirus type A9 by proteolytic enzymes. AB - The means by which coxsackievirus type A9 (CA9) is inactivated by proteolytic enzymes was investigated. After reaction of (14)C-leucine-labeled CA9 with Pronase, free leucine was liberated as measured by radiochromatography. Treatment of (14)C-leucine-labeled CA9 with trypsin or proteolytic filtrates of Pseudomonas aeruginosa caused the release of a variety of labeled substances. The extent of viral ribonucleic acid (RNA) release after exposure of CA9 to Pronase was determined by RNA infectivity tests or trichloroacetic acid solubility tests. Infective viral RNA was found not to be consistently released by reaction of CA9 with Pronase, but further treatment with 1% sodium dodecyl sulfate at pH 7.0 promoted viral RNA release. Sodium dodecyl sulfate treatment of CA9 that had not been reacted with Pronase did not inactivate virus or cause viral RNA release. Reaction of Pronase with (32)P-labeled CA9 resulted in the liberation of virus components soluble in cold trichloroacetic acid, whereas untreated CA9 or CA9 reacted with ribonuclease were precipitated by cold trichloroacetic acid. These results demonstrate that the primary means by which protease-sensitive enteroviruses are inactivated is by degradation of the virus capsid, with subsequent release of viral RNA. PMID- 4202659 TI - Immunocyte response to experimental mumps virus infection in Rhesus monkeys. AB - Nineteen rhesus monkeys were inoculated with mumps virus by retrograde ductal instillation into the parotid gland. Evidence of infection was obtained in all instances. Virus was isolated from buccal swabbings and parotid biopsies for 1 week after inoculation. A vigorous serum-neutralizing antibody response occurred within 3 weeks, and there was marked monocytic infiltration of the parotid stroma. The monocytic infiltrate comprised as much as 60% of the total gland volume 1 week after infection. The predominant inflammatory cells were non immunoglobulin-containing mononuclear cells resembling lymphocytes. Plasma cells containing immunoglobulin G (IgG), IgA, IgM, and IgE increased in numbers in the gland after infection, the greatest increase occurring in IgG-containing cells. Neutralizing antibodies and interferon were found in extracts prepared from the infected glands. Neutralizing activity was highest in samples taken 3 weeks after infection but was detectable in samples taken as soon as 36 to 48 h after infection. Interferon activity was detected in significant amounts 36 to 48 h after infection. Challenge of previously infected animals resulted in an increase in the monocytic infiltrate as well as an increase in numbers of immunoglobulin containing plasma cells. However, reinfection did not occur as evidenced by the inability to culture shed virus after challenge. This model should be useful for in vivo study of biochemical mediators which evoke inflammatory cell infiltration and which may be significant both in protection and in tissue damage. PMID- 4202660 TI - Mechanism of Shope fibroma virus-induced suppression of host deoxyribonucleic acid synthesis. AB - The effects of treatment with live or inactivated Shope fibroma virus on host cell deoxyribonucleic acid (DNA) synthesis were determined. The incorporation of (3)H-thymidine into nuclear DNA was suppressed by both active and inactivated virus, although live virus was more effective. During the early phase of infection, stimulation of host nuclear DNA synthesis of up to 240% of control value was observed in cells infected with active virus. Inhibition of DNA synthesis began at about the 8th h and was maximal by 12 h postinfection. Virus inactivated by ultraviolet-irradiation or heat treatment did not induce viral DNA synthesis but was, nevertheless, able to suppress host DNA synthesis. PMID- 4202661 TI - Rickettsial hemolysis: effect of metabolic inhibitors upon hemolysis and adsorption. AB - The hemolysis of sheep red blood cells by typhus rickettsiae is initiated by a temperature-sensitive adsorption process that is dependent on the energy generating metabolism of the rickettsaie but not that of the erythrocyte. Adsorption is followed by events dependent on the metabolism of both the rickettsaie and red blood cells. At 34 C the adsorption step is complete after about 4 min, at lower temperatures the time required for adsorption is increased. At 0 C no adsorption occurred. The addition of cyanide inhibited the catabolism of glutamate by the rickettsiae and, consequently, both adsorption and the subsequent steps in hemolysis. The starvation of the rickettsiae for glutamate also prevented adsorption. Fluoride had no demonstrable effect on rickettsial metabolism nor the adsorption step but inhibited glycolysis in the erythrocytes and the hemolysis of the erythrocytes by rickettsiae. PMID- 4202662 TI - Unique teichoic acid isolated from the cell walls of a strain of Staphylococcus aureus. AB - Teichoic acid antigen extracted from cell walls of a strain of Staphylococcus aureus has been shown to have the unique structure of glycerolphosphate, with N acetyl-d-galactosamine as the immunodominant substituent. PMID- 4202663 TI - Antibody response to chlamydia agents: lack of immunoglobulin M antibodies during the secondary immune response. AB - Intramuscular inoculation of the monkey with a massive dose of Chlamydia agent particles resulted in the production of high levels of immunoglobulin M antibodies. These antibodies were broadly specific and reacted to high titers with heterologous antigens. Challenge inoculation of the same monkeys with heterologous Chlamydia agent particles resulted in the production of increased levels of immunoglobulin G but not immunoglobulin M antibodies. Some immunological implications of these results are discussed. PMID- 4202665 TI - Gel precipitation of common enterobacterial antigen by its antibody. PMID- 4202666 TI - Observations on the cross-immunity between Theileria lawrencei (Serengeti) and Theileria parva (Muguga) in cattle. PMID- 4202664 TI - Effects of endotoxin on gluconeogenesis, glycogen synthesis, and liver glycogen synthase in mice. AB - This study was undertaken to characterize the nature of carbohydrate loss due to endotoxin poisoning in mice and to elucidate mechanisms responsible for the changes. Female ICR mice, fasted overnight, were injected intraperitoneally with a mean lethal dose of endotoxin extracted from Salmonella typhimurium strain SR 11. Liver glycogen levels, alanine-U-(14)C and pyruvate-2-(14)C incorporation into blood glucose and liver glycogen, glucose-U-(14)C incorporation into liver glycogen, and liver glycogen synthase activities were measured at intervals after treatment. Liver glycogen in fasted mice given endotoxin was diminished significantly as early as 1 h after treatment. Liver glycogen synthase was significantly decreased in poisoned mice at 17 h. The use of actinomycin D showed that the induction of this enzyme due to fasting or hydrocortisone, or both, was inhibited by endotoxin. The incorporation of the (14)C-label from alanine-U (14)C, pyruvate-2-(14)C, or glucose-U-(14)C into blood glucose and liver glycogen was substantially impaired in endotoxemic animals at 12 h. Decreases in incorporation occurred as early as 4 h after treatment. The progressive increase in glycogen synthase activity observed in fasted controls was not seen in endotoxin-poisoned mice. The administration of a glucose or pyruvate load to endotoxin-treated mice did not restore gluconeogenesis, glycogen synthesis, or liver glycogen synthase activity to normal levels. The in vivo activation of glycogen synthase by glucose was significantly reduced in endotoxemic animals. These changes indicate reduced carbohydrate synthesis as a probable cause for rapid sugar loss during endotoxemia in mice. PMID- 4202667 TI - Anoxic radiosensitization of two Bacillus species by p-nitroacetophenone. PMID- 4202668 TI - Influence of cysteamine on intramolecular energy transfer in 5-bromouracil substituted phage-DNA. PMID- 4202669 TI - Phagocytic and bacterial properties of normal human monocytes. AB - The bactericidal and phagocytic capacities of monocytes for E. coli, Staphylococcus, Salmonella, and Listeria, and factors that influence these functions were evaluated and compared with those of the polymorphonuclear leukocytes of 30 normal human subjects. Monocytes killed a significantly smaller proportion of each of the bacterial species than did neutrophils from the same individuals. Whereas the neutrophils of all individuals demonstrated the ability to kill significant numbers of the four bacterial species, there was a marked variation in the effect of monocytes of different individuals on the growth curves of these same bacteria. When the bactericidal capacity of an individual's monocytes to more than one species of bacteria was examined in the same experiment, a significant difference in the effect of monocytes on the growth curve of one bacterial species as opposed to another was noted in 4 of 17 subjects. The bactericidal ability of monocytes of single individuals was consistent on different days in 9 of the 11 subjects whose monocytes were examined more than once against the same bacteria. Studies were performed to determine if the lesser bactericidal capability of monocytes was due to a difference in the ability of monocytes and neutrophils to phagocytize or to a difference in the ability of these cells to kill ingested bacteria or both. The results demonstrated that monocytes phagocytize bacteria significantly less well than neutrophils, but the intracellular killing capacity of both cell types is equal. Addition of phenylbutazone to cell suspensions completely inhibited intracellular killing by both monocytes and neutrophils, suggesting the possibility that the bactericidal mechanisms in both cell types might be similar. Monocyte killing of E. coli, Salmonella, and Listeria, but not of Staphylococcus, was significantly diminished in heat-inactivated autologous serum. Neither increasing the concentration of autologous serum from 10% to 25% nor replacement of autologous serum with pooled human serum had any effect on monocyte killing of any of the four bacteria. These studies demonstrate that peripheral blood monocytes are less bactericidal for the four bacterial species than neutrophils, solely because monocytes are less phagocytic. A baseline for further study of factors that influence monocyte function and for study of this cell in selected patient populations is provided. PMID- 4202670 TI - Studies on derivation of transcobalamin 3 from granulocytes. Enhancement by lithium and elimination by fluoride of in vitro increments in vitamin B12-binding capacity. AB - Unsaturated vitamin B(12)-binding capacity (UBBC) of human serum is not reproducibly measurable because it increases variably in vitro in relation to time, temperature, and, in the case of plasma, anticoagulant present before removal of cells. This variable increase proved to be due to variable release in vitro of transcobalamin III (TC III) from granulocytes. UBBC increase was greatest (up to fourfold normal levels) in the presence of lithium, which is the heparin salt used in many laboratories doing UBBC studies. In vitro increase was least when blood was collected in EDTA at 0 degrees C and immediately centrifuges at 0 degrees C (T(0) sample); results equivalent to T(0) were obtained at room temperature even after several hours delay when 47 mM fluoride was present; either cold temperature or 47 mM fluoride appeared to prevent TC III release from granulocytes. The measured levels of the three transcobalamins with T(0) methods of collection, which presumably reflect most closely the in vivo circulating levels, suggest that TC I and TC III in normal plasms are of the same order of magnitude and together normally comprise less than 10% of the UBBC. Approximately 90% of the UBBC content of sonicates of peripheral blood granulocytes and of bone marrow aspirates of normal individuals appears to be TC III, with the rest being TC I. Thus, normal myelocytes, like normal granulocytes, appear to contain mainly TC III. No TC II was present in any of the sonicates. The general practice in most laboratories has been to determine serum UBBC. Because in vitro increments of up to 119% were found to occur in serum, this practice should be replaced by collection using methods that prevent such increments. Blood collected in EDTA-47 mM NaF had a stable, reproducible UBBC with no significant in vitro increment with time.EDTA-NaF UBBC was 640+/-168 (range 380-921 pg B(12) bound/ml plasma) for 12 normal adult men and 809+/-232 (range 505-1208) for normal adult women. It presumably approximates circulating UBBC and is substantially below the serum UBBC mean of 935+/-262 (range 611-1506 for the same 12 men) and 1273+/-355 (range 811-2306 for the same 10 women). PMID- 4202671 TI - Enzymatically inactive red cell carbonic anhydrase B in a family with renal tubular acidosis. AB - An inactive mutant form of red cell carbonic anhydrase B is described in three members of a large kindred who manifest infantile renal tubular acidosis and nerve deafness. A combination of enzymatic and immunologic investigations permitted its detection, despite the fact that both antigenic and electrophoretic properties of the mutant were identical to those of the normal form. PMID- 4202672 TI - Antibiotic levels in pericardial fluid. AB - An experimental model was designed to study the ability of antibiotics to enter the pericardial compartment. Noninfected and infected pericardial fluid and serum antibiotic activities were determined in adult mongrel dogs before and at intervals after antibiotic administration. After the administration of penicillin G, methicillin, cephaloridine, streptomycin, or gentamicin, clinically adequate antibiotic levels in the noninfected pericardial fluid were obtained within 1 h, and these levels approached or exceeded the serum levels within 2-4 h. Antibiotic levels obtained from infected dog pericardial fluids were higher than those from noninfected animals. Patients' serum and pericardial fluid antibiotic levels were measured after penicillin G, penicillin V, cephalothin, and gentamicin administration. We have found, both in the canine and human studies, that pericardial antibiotic levels taken at least 2 h after antibiotic administration are almost identical to those in the blood. PMID- 4202673 TI - Direct radiochemical assay for serum folate: competition between 3H-folic acid and 5-methyltetrahydrofolic acid for a folate binder. PMID- 4202674 TI - Hepatic bilirubin glucuronidation in neonates with unconjugated hyperbilirubinemia and congenital gastrointestinal obstruction. PMID- 4202675 TI - The role of medical education in planning the development of a national health care system. PMID- 4202676 TI - Some good features of the British National Health Service. PMID- 4202677 TI - The world of health and the American physician. PMID- 4202678 TI - Supervoltage isocentric arc therapy in carcinoma of the bladder. PMID- 4202680 TI - Nitroglycerin sublingual tablets. II. Preparation and stability of a new, stabilized, sublingual, molded nitroglycerin tablet. PMID- 4202679 TI - Paper chromatographic determination of tetracycline. PMID- 4202681 TI - Synthesis and biological activity of quinolyl acetic acid derivatives. PMID- 4202682 TI - Enhancement of benzalkonium chloride and chlorhexidine acetate activity against Pseudomonas aeruginosa by aromatic alcohols. PMID- 4202683 TI - Gram-negative infections in cancer. Study of empiric therapy comparing carbenicillin-cephalothin with and without gentamicin. PMID- 4202684 TI - Optimal criteria for care of patients with cancer. PMID- 4202685 TI - Pneumonia caused by Neisseria meningitidis. PMID- 4202686 TI - [Macroglobulinaemia Waldenstrom with osteolytic lesions: IgM-kappa cryoglobulinaemia with antinuclear activity and mu-chain-fragment (author's transl)]. PMID- 4202687 TI - PCB residues in plankton from the Gulf of St Lawrence. PMID- 4202689 TI - Neutron radiographic examination of soft-and hard-tissue structures of the oral cavity. PMID- 4202688 TI - Serum proteins and gestational age. PMID- 4202690 TI - Research in neurosis: a selective review. 1. Causes and courses. PMID- 4202691 TI - On the mechanism by which bovine fibrinogen induces the release and availability reaction of human blood platelets. PMID- 4202692 TI - Immunological studies on Egyptian polyvalent antivenins. PMID- 4202693 TI - Phospholipase isoenzymes from Naja naja venom. I. Purification and partial characterization. PMID- 4202694 TI - Antiendotoxin effect of disodium cromoglycate. PMID- 4202695 TI - [Morphometric analysis of Macaca mulatta monkey chromosomes]. PMID- 4202696 TI - Blood parasites of the Impala (Aepyceros melampus) in the Serengeti National Park. PMID- 4202697 TI - Distribution and persistence of polychlorinated biphenyls (Aroclor 1254) in growing piglets. PMID- 4202698 TI - [Determination of resistance of Mycobacterium tuberculosis against isonicotinic acid hydrazide, streptomycin, para-aminosalicylic acid, ethionamide, ethambutol and rifampicin using the 32 P incorporation test]. PMID- 4202699 TI - A clinical study of the benzodiazepine Ro 5-4023 (clonazepam) in the treatment of epilepsy. PMID- 4202700 TI - Congenital defects of the corpus callosum. Morphology and encephalographic appearances. PMID- 4202701 TI - Drug susceptibility-resistance pattern of gram-negative uropathogens to seven cephalosporins. PMID- 4202702 TI - Analytical methodology for bioactive compounds. Photochemically assisted analysis of chlorinated hydrocarbon pesticides in the presence of polychlorinated biphenyls. PMID- 4202703 TI - Microdilution antibiotic susceptibility test: examination of certain variables. AB - A semiautomated microdilution susceptibility test is described. The effect of certain parameters such as inoculum size, growth media, incubation conditions, and inoculum dispensing systems was studied. Both medium type and inoculum size caused significant variations in the minimum inhibitory concentrations (MIC) of certain antibiotic-organism combinations. No effect on MIC was observed as a function of incubator type. Efforts to read a reproducible MIC value in less than 12 h failed. A commercially available wire pronged inoculator was determined to be inaccurate and unsafe. Disposable dropper pipettes proved to be economical, accurate, and precise. Although a standard method for microdilution antibiotic susceptibility testing is not proposed, data are presented which show that future attempts at standardized procedures are mandatory if inter- and intralaboratory reliability is desired. PMID- 4202704 TI - Development and evaluation of a direct fluorescent antibody method for the diagnosis of Pneumocystis carinii infections in experimental animals. AB - Because no fully satisfactory diagnostic method has been available for use in pneumocystis infection, an attempt was made to apply the fluorescent antibody technique in the identification of Pneumocystis carinii. Hyperimmune sera were prepared in rabbits against P. carinii from human and rat sources. After proper adsorption, these antisera were conjugated with fluorescein isothiocyanate and used as reagents in a direct fluorescent antibody procedure. Each of the two reagents was found to stain trypsin-treated P. carinii organisms from either human or rat sources, indicating the presence of common antigens. Stained organisms were demonstrated in the hypopharyngeal material from rats in which pneumocystis infection had been activated by the administration of corticosteroid. From the results reported here, the procedure outlined is considered sufficiently sensitive and specific to justify tests on pneumocystis infections in man. The findings in a series of specimens from human subjects will be reported separately. The method also provides an extended approach to related research problems. The need for controls of the procedure at all points is emphasized. PMID- 4202705 TI - Method for the selective enumeration of blue-green bacteria in water. AB - A membrane filter method for the selective enumeration of blue-green bacteria has been developed which, on the basis of studies with laboratory cultures and field tests, has proved to be both practical and reproducible. The filters are incubated under specified conditions of temperature and illumination on a mineral salts agar medium supplemented with yeast extract and containing cycloheximide to eliminate eukaryotic contaminants. PMID- 4202706 TI - Effects of changes in feed level, starvation, and level of feed after starvation upon the concentration of rumen protozoa in the ovine. AB - Four rumen fistulated sheep were used in five experiments to investigate the effect of feed level upon the concentration of rumen ciliate protozoa. The sheep were fed once daily 650 g of a pelleted diet composed of corn cobs, 45%; alfalfa meal, 35%; oats, 12.5%; cane molasses, 5%; urea, 0.4%; and vitamins and minerals, 2%. The concentration of protozoa reached minimum and maximum values at 5 and 22.5 h after feeding, respectively. Thus, to estimate apparent generation rates, concentrations of protozoa were determined at 5 and 20 h postfeeding. Apparent generation rate/h = natural log of ([concentration of protozoa at 20 h divided by concentration at 5 h] divided by the time interval, [T20 to T5]). Alteration of the feed to protozoa ratio by starvation and by changing the level of feed (200 to 900 g/day) showed that as the ratio of feed to protozoa increased, generation rate increased. Measurements of liquid turnover rates in the rumen showed that turnover rate decreased as feed level decreased. Turnover rate was near zero when the sheep were starved. Small quantities of soluble substrates, added directly to the rumen of starved sheep, maintained the protozoal population when rumen turnover was minimal. Furthermore, as rumen turnover rate increased with increased levels of feed, the effect of substrate on maintaining the protozoal population was negated. Thus, at high feed levels, turnover rate may be the dominant factor controlling the establishment and concentration of protozoa in the rumen. PMID- 4202707 TI - Effect of propylene oxide treatment on the microflora of pecans. AB - Studies were conducted to determine the effectiveness of propylene oxide (PO) treatment in controlling the microflora of pecans. As used commercially, PO has little effect on internal bacteria and fungi in pecan halves. Tests of surface washings of commercially treated pecans showed a reduction of 96% in coliform bacteria following PO treatment. Under controlled laboratory conditions, PO gave 80 to 92% reduction of surface microflora and at least 64% reduction of internal flora, but neither bacteria nor fungi could be eliminated completely, even with high dosages. Current assay methods for determining bacterial content of nutmeats were shown to be inadequate because they utilize only surface washings and thus do not give an accurate picture of the total bacterial population of the nutmeat. Consequently, such assays do not permit an accurate assessment of any potential health hazard related to these organisms. PMID- 4202708 TI - New toxin from Aspergillus flavus. AB - Two nonaflatoxin-producing isolates of Aspergillus flavus produced a new nonfluorescent nitrogen-containing metabolite that was highly toxic to 1-day-old cockerels. The oral mean lethal dose of toxin was 19 mg/kg. Chemical and physical data obtained on the purified toxin demonstrated that it was not one of the previously reported metabolites of A. flavus. The common name "flavutoxin" has been assigned to the toxin. PMID- 4202709 TI - Distribution of pyrimidine oligonucleotides in complementary strand fractions of Escherichia coli deoxyribonucleic acid. PMID- 4202710 TI - Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma. PMID- 4202711 TI - Carbonic anhydrase catalyzed hydrolysis and decarboxylation. Kinetic studies of enzyme-catalyzed decomposition of mono- and disubstituted derivatives of carbonic acid. PMID- 4202712 TI - Multiple forms of galactosyltransferase from bovine milk. PMID- 4202713 TI - Human erythrocyte phosphoglycerate kinase: purification, properties, and interaction with its antibody. PMID- 4202715 TI - The effects of Ca2+ on procine enteropeptidase activity. PMID- 4202714 TI - Purification and some properties of rat spleen phospholipase A. PMID- 4202716 TI - Inactivation of infectious deoxyribonucleic acid of bacteriophage phi chi X 174 by colicin E2. PMID- 4202717 TI - Gel electrophoresis of RNA under denaturing conditions. PMID- 4202718 TI - Further studies of the fluorescent treponemal antibody-cerebrospinal fluid (FTA CSF) test with a monospecific anti-IgM conjugate. PMID- 4202719 TI - Gonococcal pharyngeal infections. Report of 110 cases. PMID- 4202720 TI - Neisseria gonorrhoeae identified by the direct fluorescent antibody technique in male contacts. PMID- 4202722 TI - Asymptomatic meningococcal urethritis. Possible protective value against gonococcal infection by bacteriocin production. PMID- 4202721 TI - Studies in venereal disease. II. Improved diagnosis of gonorrhoea by the parallel use of conventional and L-phase media for culture. PMID- 4202723 TI - Comparison of trimethoprim-sulphamethoxazole and penicillin in the treatment of gonorrhoea. PMID- 4202724 TI - Long-term triple tetracycline ("Deteclo") treatment of non-specific urethritis. PMID- 4202725 TI - Sialic acid content of red blood cells from protein-calorie malnourished children and during recovery, and from normal children and adults. PMID- 4202726 TI - [Penetration of radioactive material into biological tissue]. PMID- 4202727 TI - Editorial: Carbon monoxide, smoking and cardiovascular disease. PMID- 4202728 TI - Salicylamide glucuronide formation in newborns with severe jaundice of unknown etiology and due to glucose-6-phosphate dehydrogenase deficiency in Greece. PMID- 4202729 TI - Fab-related fragments of human IgG produced by partial tryptic proteolysis. PMID- 4202730 TI - Isolation of immunochemically pure IgE from serum of E-myeloma patient Yu. PMID- 4202731 TI - Formation of a hemolytically active cellular intermediate by the interaction between properdin factors B and D and the activated third component of complement. AB - The present studies demonstrate that the factor B-dependent C3 convertase can be affixed to an erythrocyte by use of an intermediate bearing C3b and that this convertase brings the hemolytic reaction to completion with an efficiency comparable to that of classical convertase. The evidence that the EAC43 intermediate was lysed by a new pathway includes requirements for factors B and D and cell-bound C3b for subsequent lysis by the terminal components, C3-C9. The linear stoichiometry of the effective molecule titrations of C3b and factor B, and the first-order kinetics displayed by the generation and decay of the factor B-dependent hemolytic site are characteristics consistent with the one-hit theory as initially developed for the classical complement system. The use of hemolytically active cellular intermediates to examine the reactions occurring with C3b and factors B and D has allowed extension of the one-hit theory to this molecular sequence, development of effective molecule titrations, recognition of the analogies to the functional characteristics of the classical C3 convertase, and discrimination of the probable mechanism of terminal complement activation from reactive lysis. PMID- 4202732 TI - Influence of erythrocyte membrane components on malaria merozoite invasion. AB - Chymotrypsin- and Pronase-treated human erythrocytes were refractory to invasion by P. knowlesi merozoites; invasion was not inhibited by trypsin or neurammidase treatment. These data implicate a surface protein other than sialoglycoprotein as the receptor site for merozoites. Invasion of rhesus erythrocytes was unaffected by pretreatment with these enzymes. Differences in membrane structure of erythrocytes from various species may explain the absence of an enzyme effect on rhesus erythrocytes. PMID- 4202733 TI - The usefulness of thyrotropin-releasing factor (TRF) test in patients with hypothalamic-pituitary disorders. PMID- 4202734 TI - New aspects in the biological role of zinc: a stabilizer of macromolecules and biological membranes. PMID- 4202735 TI - Methadone inhibition of glycogen synthase and phosphorylase in rat skeletal muscle. PMID- 4202736 TI - A kinetic study of the participation of zinc in human spermatozoa metabolism. PMID- 4202737 TI - Antigenic independence of the two types of alkaline phosphatases from Serratia marcescens strain 211. PMID- 4202738 TI - [Progress in the concept and diagnosis of Marfan's syndrome]. PMID- 4202739 TI - Inhibition of insulin release during hypovolemic shock. PMID- 4202740 TI - HMO performance: the recent evidence. PMID- 4202741 TI - Willebrand factor: immunological and biological study. PMID- 4202742 TI - Proceedings: Perhexiline versus prenylamine. A controlled clinical trial in coronary insufficiency. PMID- 4202744 TI - Proceedings: Experience with the use of perhexiline in patients with chronic coronary insufficiency: preliminary report. PMID- 4202743 TI - [Proceedings: Review of the cardiovascular pharmacology of perhexiline]. PMID- 4202745 TI - Effect of ageing on the levels of the main classes of serum immunoglobulins in active chronic hepatitis and in clinically healthy subjects. PMID- 4202746 TI - [Problems with the parenteral feeding of patients unconscious for a long period of time]. PMID- 4202747 TI - [Side effects from high voltage therapy of carcinoma of the prostate (author's transl)]. PMID- 4202748 TI - [Comparison of the immunological and morphological changes in hepatic tissue due to beta-naphthylamine]. PMID- 4202749 TI - [Automatic apparatus for the elaboration of conditioned reflexes in apes in the primatological chair]. PMID- 4202750 TI - Hog cholera (European swine fever). PMID- 4202751 TI - Pharmacokinetic evaluation of penicillin and cephalosporin derivatives in serum and milk of lactating cows and ewes. PMID- 4202752 TI - Biphenyl-exposed rabbits. PMID- 4202753 TI - [Microflora of the purulent inflammatory foci of the otorhinolaryngologic organs and its relation to antibiotics]. PMID- 4202754 TI - Control of magnesium-protoporphyrin chelatase activity in Rhodopseudomonas spheroides. Role of light, oxygen, and electron and energy transfer. AB - 1. Magnesium-protoporphyrin chelatase activity, previously shown in whole cells of Rhodopseudomonas spheroides, could not be demonstrated in cell-free extracts prepared in different ways, although spheroplasts retained moderate activity. Slight activity was detected also in whole cells of Rhodospirillum rubrum. 2. The effects on the activity of the enzyme of inhibitors of electron and energy transfer were studied in whole cells of Rps. spheroides. Amytal, rotenone, azide and cyanide inhibited at low pO(2) in the dark but not under anaerobic conditions in the light. Antimycin A and 2-heptyl-4-hydroxyquinoline N-oxide, as well as uncouplers and oligomycin, inhibited under all environmental conditions. 3. The effects on magnesium chelatase activity of intermediates of the tricarboxylic acid cycle, of thenoyltrifluoroacetone, of a number of artificial electron donors or acceptors, of various quinones and of the oxidation-reduction indicator dyes Benzyl Viologen and Methyl Viologen are described. 4. It was concluded that electron transport between a b-type and a c-type cytochrome as well as associated energy conservation and transformation reactions were essential for activity. There was also a specific requirement for ATP. 5. Exogenous protoporphyrin and magnesium protoporphyrin monomethyl ester were incorporated into bacteriochlorophyll or late precursors by whole cells. 6. Evidence is presented that the insertion of magnesium was the only step inhibited by oxygen in the biosynthetic pathway between protoporphyrin and bacteriochlorophyll. PMID- 4202756 TI - Stimulation of non-conservative DNA synthesis by ultraviolet light in freeze treated Bacillus subtilis. PMID- 4202755 TI - Binding of parathyroid hormone to bovine kidney-cortex plasma membranes. AB - 1. Plasma membranes were purified from bovine kidney cortex, with a fourfold increase in specific activity of parathyroid hormone-sensitive adenylate cyclase over that in the crude homogenate. The membranes were characterized by enzyme studies. 2. Parathyroid hormone was labelled with (125)I by an enzymic method and the labelled hormone shown to bind to the plasma membranes and to be specifically displaced by unlabelled hormone. Parathyroid hormone labelled by the chloramine-t procedure showed no specific binding. (75)Se-labelled human parathyroid hormone, prepared in cell culture, also bound to the membranes. 3. Parathyroid hormone was shown to retain biological activity after iodination by the enzymic method, but no detectable activity remained after chloramine-t treatment. 4. High concentration of pig insulin inhibited binding of labelled parathyroid hormone to plasma membranes and partially inhibited the hormone-sensitive adenylate cyclase activity in a crude kidney-cortex preparation. 5. EDTA enhanced and Ca(2+) inhibited binding of labelled parathyroid hormone to plasma membranes. 6. Whereas rat kidney homogenates were capable of degrading labelled parathyroid hormone to trichloroacetic acid-soluble fragments, neither crude homogenates nor purified membranes from bovine kidney showed this property. 7. Binding of parathyroid hormone is discussed in relation to metabolism and initial events in hormone action. PMID- 4202757 TI - Translational inhibition in extracts from serum-deprived animal cells. PMID- 4202758 TI - [Conservative or operative treatment in acute pancreatitis]. PMID- 4202759 TI - Maternal age effect associated with yellow pigment in Malpighian tubes of Drosophila melanogaster. PMID- 4202760 TI - Growth and enterotoxin B synthesis by Staphylococcus aureus S6 in associative growth with Pseudomonas aeruginosa. PMID- 4202762 TI - Growth of Streptococcus cremoris and Streptococcus lactis in a chemostat. Production of cells and survival of bacteria during frozen storage. PMID- 4202761 TI - Purification and characterization of Pseudomonas aeruginosa alkaline phosphatase. PMID- 4202763 TI - [Effects of glucocorticoid on TSH secretion--clinical and experimental evaluation using synthetic TRF]. PMID- 4202765 TI - Chapter 30. Current status of spinal cord cooling. PMID- 4202764 TI - [Experimental and clinical evaluation of HTSH kit, no.1]. PMID- 4202766 TI - [Visual orientation of primates and connected learning- and abstraction performances]. PMID- 4202767 TI - Sedimentation characteristics of thyroglobulin in some amphibians after 131-I iodination in vivo. PMID- 4202768 TI - Thymidylate synthetase in mutants of Drosophila melanogaster. AB - Thymidylate synthetase has been examined with respect to the normal pattern of activity throughout the development of the Oregon-R strain of Drosophila melanogaster. Large amounts of the enzyme are present in both the unfertilized and the fertilized eggs. A comparison of the ovarian thymidylate synthetase activity of the Oregon-R strain and the female sterility mutants, fs(2)B, fu, and fs(1)N, indicates variations in the activity of this enzyme in each strain. At four days of age, the ovarian-specific activity of the female sterility mutants is comparable to or less than that of the Oregon-R strain, but it is reduced at fifteen days of age. The enzyme activity per ovary is low in the fs(2)B strain but is similar in the Oregon-R, fu, and fs(1)N strains. When expressed as activity per organism, thymidylate synthetase declines after six to eight hours of development until the minimal level is reached in the late embryonic stage. Enzyme activity rises throughout the larval instars, reaching a maximum immediately after puparium formation. The activity decreases during pupation, but rises again during the first four days of adult life. PMID- 4202769 TI - Gene conversion and transfer of genetic information within the inverted region of inversion heterozygotes. AB - Prior studies of recombination which monitor exchange events in exceedingly short intervals (i.e., separable sites within a cistron) reveal that the basic event in recombination involves a non-reciprocal transfer of information, termed conversion. As a logical consequence of the model suggested by the work in Drosophila, the present investigation examined recombination between rosy mutant alleles (ry:3-52.0) in Drosophila melanogaster in a paracentric inversion (In(3R)P(18)) heterozygote, which placed the rosy region approximately at the center of the inverted region. Comparison of the results of this study with experiments carried out in standard chromosome homozygotes reveals a dramatic suppression of classical crossovers between the rosy mutant alleles in the inversion heterozygote. However, conversions continue to occur for all rosy mutant alleles in all heterozygous combinations in the inversion heterozygote. Moreover, the order of magnitude of conversion frequencies seen in the inversion heterozygote does not change from that seen in the standard chromosome homozygote study. The significance of these observations with reference to the role of rearrangements as barriers of information transfer is discussed. Particular attention is directed to the elaborate inversion polymorphisms seen in natural populations, and to notions concerning their role in the evolution of adaptive gene complexes. PMID- 4202770 TI - A case of high rate of spontaneous mutation affecting viability in Drosophila melanogaster. AB - A spontaneous lethal mutation rate approximately twenty to thirty times greater than normal has been discovered in second and third chromosomes derived from an irradiated isogenic line and paired with marked inversion chromosomes. Mutations resulting in reductions of viability of varying magnitude short of complete lethality apparently also occur at a very high rate in the third but not in the second chromosome. The pattern of accumulation of lethal mutations over several generations and viability frequency distributions within generations have been studied in a number of independent experiments. High mutation rate occurs in heterozygous isogenic-derived second and third chromosomes, either together or apart, irrespective of the genetic constitution of nonhomologous chromosomes. High mutation rates were not observed using the same methods with chromosomes of an inbred line from a different source. The possible mechanisms responsible for these results are discussed. PMID- 4202771 TI - Segmental aneuploidy as a probe for structural genes in Drosophila: mitochondrial membrane enzymes. AB - A method for detecting possible structural genes in D. melanogaster based on gene dosage dependency is presented. By making thirty crosses between Y-autosome translocations, and an attached-4 cross, it is possible to produce large duplications (approximately 150 salivary gland chromosome bands in length) for every autosomal region with the exception of 83DE. The usefulness of the technique was demonstrated by dosage dependency of three known gene-enzyme systems: alpha-glycerophosphate dehydrogenase-1, alcohol dehydrogenase and malate dehydrogenase. A screen for genes affecting two enzymes localized on the inner membrane of the mitochondrion, alpha-glycerophosphate oxidase (alphaGPO) and succinic dehydrogenase (SHD), produced a dosage-sensitive region in each case. Region 50C-52E affected alphaGPO activity and region 28D-29F affected SDH activity. The latter region apparently includes the malic dehydrogenase-1 gene. The methodology and limitations of the technique are discussed. PMID- 4202772 TI - The crossveinless polygenes in an Iowa population. AB - A natural population of Drosophila melanogaster was tested for the presence of crossveinless (cve) alleles over the course of a summer. Approximately 8% of the wild-caught females tested carried enough cve alleles to produce true-breeding crossveinless lines. In some cases, different isofemale lines produced identical cve strains. Also, differences were sometimes observed among independently selected cve sublines of a given isofemale line.-The cv-2 allele was found to occur with a frequency of about 1% to 2%. PMID- 4202773 TI - The genetic control and biochemical modification of catechol oxidase in maize. AB - Three isozyme variants of catechol oxidase have been shown to be determined by alleles of a gene, Cx, which has been located on chromosome 10 less than 0.1 recombination units from the endosperm marker du(1).-The extractable form of the enzyme is modified by an endogeneous "modifier" which appears to function as an enzyme substrate. Enzyme and modifier are functionally isolated in intact cells. Modified enzyme has altered kinetics, does not migrate in electrophoresis and most probably results from a "tanning" of the enzyme by reaction products. The content of modifier varies in different lines and is genetically determined by gene(s) independent of Cx. Treatment with maleic hydrazide causes a ten-fold reduction in the modifier content of seedlings, allowing the enzyme to be extracted in an unmodified form which will migrate in electrophoresis.-This system of enzyme and modifier fits the requirements of hypersensitive disease resistance in plants and may provide a test system to investigate the biochemical basis of disease resistance. PMID- 4202774 TI - Carbonic anhydrase activity in amphibian and reptilian lung: a histochemical and biochemical analysis. PMID- 4202775 TI - [Nitromint, nitropenton and rausedyl intoxication caused acute renal insufficiency]. PMID- 4202776 TI - Dermatological aspects of pseudo-Hurler polydystrophy (mucolipidosis 3). PMID- 4202777 TI - Energy-dependent release of magnesium from beef heart submitochondrial particles. PMID- 4202778 TI - Denaturation of bovine carbonic anhydrase B by guanidine hydrochloride. A process involving separable sequential conformational transitions. PMID- 4202779 TI - Purification and properties of a progesterone-induced basic glycoprotein from the uterine fluids of pigs. PMID- 4202780 TI - Noninvolvement of copper in the L-tryptophan 2,3-digoxygenase reaction. PMID- 4202781 TI - Control of metabolite secretion in Bacillus subtilis. PMID- 4202782 TI - Chemotactic responses by motile bacteria. PMID- 4202783 TI - The relationship between the O-antigenic lipopolysaccharides and serological specificity in strains of Pseudomonas aeruginosa of different O-serotypes. PMID- 4202784 TI - The metabolism of 2-oxogluconate by Pseudomonas aeruginosa. PMID- 4202785 TI - Temperature-sensitive events in the growth of alastrim virus in chick embryo cells. PMID- 4202786 TI - The effect of trypsin on the formation of virus-specific surface antigen in cowpox virus-infected cells. PMID- 4202787 TI - Spread of bovine syncytial virus in cell culture. PMID- 4202788 TI - A population model for limited food competition. PMID- 4202789 TI - Tonic communication: continual effects of discrete signs in animal communication systems. PMID- 4202790 TI - Molecular evolution of myoglobin and the fossil record: a phylogenetic synthesis. PMID- 4202791 TI - [Origins of syphilis]. PMID- 4202792 TI - [Radioprotective effect of mexamine on oral administration to monkeys]. PMID- 4202793 TI - Immune response to C. albicans in monkeys with experimental candidiasis in the palate. PMID- 4202794 TI - Histologic variations in the pulp of intact premolars from young individuals. PMID- 4202796 TI - [Case of acute dysphagia against the background of esophageal diverticula]. PMID- 4202795 TI - Alkaline phosphatase in the enamel organ of the rat incisor. PMID- 4202798 TI - [Behavior of serum glycoproteins in diabetic retinopathy]. PMID- 4202797 TI - [Hypertrophic osteodermopathy (systemic ossifying periostosis associated with cutis verticis gyrata)]. PMID- 4202800 TI - Demonstration of thyroglobulin in lymph vessels of TSH stimulated guinea pigs by the indirect immunofluorescence technique. PMID- 4202799 TI - The metabolism of ibuprofen. PMID- 4202801 TI - Endocrine changes before and after the menarche. 3. Total thyroxine and "free thyroxine index", and the binding capacity of thyroxine binding proteins in female adolescents. PMID- 4202802 TI - Peripheral plasma levels of oestrone, oestradiol-17beta and progesterone during ovulatory menstrual cycles in the rhesus monkey with special reference to the onset of menstruation. PMID- 4202803 TI - Patterns of circulating oestrone, oestradiol-17beta and progesterone during pregnancy in the rhesus monkey. PMID- 4202804 TI - Congenital diverticulum of the left ventricle. PMID- 4202805 TI - The arterial supply to the lumbo-sacral spinal cord in the monkey: a comparison with man. PMID- 4202806 TI - I segment lengths and thin filament periods in skeletal muscle fibers of the Rhesus monkey and the human. PMID- 4202807 TI - Primary intraorbital meningiomas. PMID- 4202808 TI - Changes in blood methanol concentrations in chimpanzees during periods of chronic ethanol ingestion. PMID- 4202809 TI - Barbiturate inhibition of growth and of synthesis of deoxyribonucleic acid, ribonucleic acid and protein in cultured mammalian cells. PMID- 4202810 TI - Presence of histaminase and ornithine decarboxylase activities in rat thymus. PMID- 4202812 TI - [Biosynthesis and properties of the polypeptide antibiotic nisin]. PMID- 4202811 TI - Effect of cholinesterase inhibitors on active potassium influx in monkey erythrocytes. PMID- 4202813 TI - [Respiration of the blue-green alga Plectonema boryanum]. PMID- 4202814 TI - [Changes in intracellular potential in Spirostomum ambigum infusoria during habituation]. PMID- 4202815 TI - Malignant lymphoma with a monoclonal F(ab)mu fragment. PMID- 4202816 TI - Immunobiology of human anti-IgM iso-antibodies. I. Clinical and serological studies. PMID- 4202817 TI - An alpha heavy chain abnormality in a child with hypogammaglobulinemia. PMID- 4202818 TI - Isolation and characterization of a non-specific esterase enzyme of Ascaris suum perienteric fluid. PMID- 4202819 TI - Disc electrophoresis of Ascaris suum female reproductive system esterase enzymes. PMID- 4202820 TI - 1 Anilino-8-naphthalene sulfonate and n-phenyl-1-naphthylamine as the indicators of bacterial thermosensitivity. PMID- 4202821 TI - Identification of a large fragment after limited cyanogen bromide cleavage of fibrinogen. PMID- 4202822 TI - Evidence for a novel DNA component in chloroplasts of Euglena gracilis. PMID- 4202823 TI - On the specificity of antisera against prostaglandins A2 and E2. PMID- 4202824 TI - Variable J-chain content in human IgM. PMID- 4202826 TI - Analytical determination of the buoyant density of DNA in acrylamide gels after preparative CsCl gradient centrifugation. PMID- 4202825 TI - A glycosphingolipid sharing reactivity with both wheat germ lectin and "carcinoembryonic antisera (Gold)": partial identity of these reactive sites. PMID- 4202827 TI - Urinary proteins of the normal rat. PMID- 4202828 TI - Humoral and cellular immunity in the anergic tuberculosis patient. A prospective study. PMID- 4202830 TI - The structural gene for the ribosomal protein S18 in Escherichia coli. II. Chemical studies on the protein S18 having an altered electrophoretic mobility. PMID- 4202829 TI - Role of adipose tissue lipolysis in postnatal amelioration of thermogenesis in domestic and wild piglets. PMID- 4202831 TI - Fine structure and life cycle of Lankesteria clarki sp. n. (Sporozoa: Eugregarinida) parasitic in the mosquito Aedes sierrensis (Ludlow). PMID- 4202832 TI - Immunogenicity and infectivity of sporozoites of mammalian malaria isolated by density-gradient centrifugation. PMID- 4202833 TI - DNA and RNA syntheses by intraerythrocytic stages of Plasmodium knowlesi. PMID- 4202834 TI - Localization of some enzymes of beta-oxidation of fatty acids in the peroxisomes of Tetrahymena. PMID- 4202836 TI - [Demonstration of circulating antibodies against antigens of the gastric and oesophageal mucosa in gastro-intestinal diseases (author's transl)]. PMID- 4202837 TI - Hormonal responses to intravenous alimentation. PMID- 4202838 TI - Filter system for intravenous alimentation. PMID- 4202835 TI - [Copper, iron, ceruloplasmin and transferrin in plasma of chronic dialysis patients (author's transl)]. PMID- 4202839 TI - Alteration in heterocyst pattern of Anabaena produced by 7-azatryptophan. PMID- 4202840 TI - Slow rate of evolution of alpha A chain of alpha-crystallin. PMID- 4202841 TI - Supraspinal control over segmental centers of antagonist muscles in man. 3. Tuning of spinal reciprocal inhibition system during organization preceding voluntary movement. PMID- 4202842 TI - Memory establishment via the anterior commissure of monkeys. PMID- 4202843 TI - A general theory of carcinogenesis. AB - A GENERAL HYPOTHESIS OF CARCINOGENESIS IS PROPOSED CONSISTING OF THE FOLLOWING FEATURES: (1) It is suggested that all cells possess multiple structural genes (Tr) capable of coding for transforming factors which can release the cell from its normal constraints on growth. (2) In adult cells they are suppressed by diploid pairs of regulatory genes and some of the transforming genes are tissue specific. (3) The Tr loci are temporarily activated at some stage of embryogenesis and possibly during some stage of the cell cycle in adult cells. (4) Spontaneous tumors, or tumors induced by chemicals or radiation, arise as the result of a double mutation of any set of regulatory genes releasing the suppression of the corresponding Tr genes and leading to transformation of the cell. (5) Autosomal dominant hereditary tumors, such as retinoblastoma, are the result of germ-line inheritance of one inactive regulatory gene. Subsequent somatic mutation of the other regulatory gene leads to tumor formation. (6) The Philadelphia chromosome produces inactivation of one regulatory gene by position effect. A somatic mutation of the other leads to chronic myelogenous leukemia. (7) Oncogenic viruses evolved by the extraction of host Tr genes with their conversion to viral transforming genes. As a result, in addition to the above mechanisms, tumors may also be produced by the reintroduction of these genes into susceptible host cells. PMID- 4202844 TI - The presence of ribonucleotides in mature closed-circular mitochondrial DNA. AB - Mitochondrial DNA from mouse and HeLa cells is nicked by alkali and chick-embryo ribonuclease H. It has been concluded that ribonucleotides are present in the closed-circular duplex. A comparative study of the scission rates at pH 13.0 of RNA and of mitochondrial DNAs indicates that there are no more than 10 ribonucleotides in the major fraction of the mitochondrial DNAs. PMID- 4202845 TI - Production of a noncovalently bonded pentamer of immunoglobulin M: relationship of J chain. AB - Human immunoglobulin M was reduced with concentrations of 2-mercaptoethylamine chosen so that approximately 40% of the immunoglobulin M was reduced to 7S subunits. Under these conditions, which selectively cleave intersubunit disulfides, J chain was released. The 7S subunits of immunoglobulin M so produced did not contain J chain. The high-molecular-weight immunoglobulin M remaining after treatment with 2-mercaptoethylamine had a sedimentation coefficient of 18.0 S and molecular weight of 1 million, and dissociated in 4 M guanidine into subunits similar in size to the 7S subunits. J chain was found in the 18.0S, noncovalently linked immunoglobulin M from which it was released only after more complete reduction with 10 mM dithiothreitol. The results are consistent with the hypothesis that J chain participates in the formation of the intersubunit linkages. However, it need not necessarily be directly involved in all of the intersubunit disulfides. It may play an important role in modulating the assembly of immunoglobulin M subunits, perhaps by inducing conformational changes that lead to noncovalent interactions between the subunits. PMID- 4202846 TI - On the amino-acid sequence of flagellin from Bacillus subtilis 168: comparison with other bacterial flagellins. AB - A partial amino-acid sequence of Bacillus subtilis 168 flagellin is presented. The region of unassigned sequence in this 304-residue polypeptide chain spans residues 158-173. Comparison of the 27-residue aminoterminal CNBr peptide of B. subtilis 168 flagellin with that derived from the flagellin of the serologically unrelated strain of B. subtilis, W23, shows only three conservative substitutions, whereas the 16-residue carboxyl-terminal peptides derived from these flagellins were identical. The comparison of the very limited sequence information available on the flagellins of Salmonella and Proteus with that on B. subtilis indicates homology between these proteins. PMID- 4202847 TI - A wet chemical method for rendering scanning electron microscopy samples conductive and observations on the surface morphology of human erythrocytes and Ehrlich ascites cells. AB - An alternate method to the common technique of evaporating a metallic coating on cells to render them conductive for scanning electron microscopy is described. This wet chemical technique is less expensive and easier to use, but is not as widely applicable as the evaporative technique. It should prove invaluable in the identification of artifacts by comparison of micrographs of material prepared in both manners. The first step in our application of this wet chemical method is to use the Centrifugal Cytology bucket to deposit the cells onto conductive polyethylene. After centrifugation and fixation with 4% glutaraldehyde, the sample is placed in a 50% glutaraldehyde solution. After a rinse in distilled water it is treated with ammoniacal silver nitrate. The reduced silver renders the sample conductive and, thus, for erythrocytes, eliminates artifacts due to charging and reduces these artifacts to virtually acceptable levels for larger cells. The surfaces of erythrocytes appear smooth with this technique while those coated by conventional vapor deposition of Au-Pd alloys often appear slightly wrinkled. Ehrlich ascites cells apparently can be divided into two classes by surface morphology. The surface structure of Ehrlich ascites cells rendered conductive by the wet method appears to be finer than conventionally prepared ones. PMID- 4202848 TI - [Is there a relationship between the level of haptoglobulins and the intensity of diphenylamine reaction in the serum of patients with rheumatic disease]. PMID- 4202849 TI - [Heat resistance and electrogenesis of animal cells in the light of Orbeli's concepts on the evolution of functions and functional evolution]. PMID- 4202850 TI - [Information values of the dynamics of nerve cell impulse activity]. PMID- 4202852 TI - The projections of the medial geniculate complex within the sylvian fissure of the rhesus monkey. PMID- 4202851 TI - Thrombogenic properties of heparinised vascular catheters. PMID- 4202853 TI - The visuotopic organization of the superior colliculus of the owl monkey (Aotus trivirgatus) and the bush baby (Galago senegalensis). PMID- 4202854 TI - Changes in cerebroside synthetic activities of the brain with development of the rhesus monkey (Macaca mulatta). PMID- 4202855 TI - Two cases of apparent exclusion of maternity caused by Rh chromosome deletion. PMID- 4202856 TI - Planning the nutrition component of long-term care. PMID- 4202857 TI - Effects of protein deficiency on serum albumin-synthesizing activity of rat liver -with special reference to the presence of transcriptional controls. PMID- 4202858 TI - Immunological studies on the light chains of myosin with special reference to the relationship between light chain components. PMID- 4202859 TI - The purification and properties of cytidine deaminase from Escherichia coli. PMID- 4202861 TI - Further studies on a specific basic protein from bread wheat. PMID- 4202860 TI - [Lividomycin therapy in intestinal infections with special reference to the combined use of lividomycin and AB-PC]. PMID- 4202862 TI - A study on antibodies produced with liver tissue containing Australia antigen and virus-like particles. PMID- 4202864 TI - Rapid diagnosis of pulmonary mycosis by counterelectrophoresis. PMID- 4202865 TI - [Current views on acute ulcerative necrotizing gingivitis]. PMID- 4202863 TI - Experimental avian aspergillosis. PMID- 4202866 TI - [Nicotinic stomatitis (case report)]. PMID- 4202868 TI - [Arrangement of teeth in immediate dentures]. PMID- 4202867 TI - [Protection of defective teeth with temporary crowns]. PMID- 4202869 TI - [Long term care in Sweden]. PMID- 4202870 TI - [Role of bivalent metal ions in the formation of the structure of polytene chromosomes]. PMID- 4202871 TI - [Sensitivity of the ciliate Colpoda maupasi to short-wave UV radiation at a temperature of 0 degrees]. PMID- 4202872 TI - [Preoperative chemotherapy of malignant ovarian neoplasms]. PMID- 4202873 TI - [Comparative physiological aspects of the study of complex forms of animal behavior]. PMID- 4202874 TI - The effect of plasma and plasma derivative infusion in the mucopolysaccharidoses. PMID- 4202875 TI - Left ventricular volume changes after amyl nitrite and nitroglycerin in man as measured by ultrasound. PMID- 4202876 TI - [Letter: Duodenal diverticulosis]. PMID- 4202877 TI - Genetic polymorphism of mannosephosphate isomerase in Primates. PMID- 4202878 TI - Genetic polymorphism of isocitrate dehydrogenase in Primates. PMID- 4202879 TI - Transspecific variability of carbonic anhydrase I in Primates. PMID- 4202880 TI - Genetic polymorphism of liver esterases in Primates. I. Papio cynocephalus (Linnaeus, 1766). PMID- 4202881 TI - Titres of Australia (hepatitis-associated) antigen in healthy carriers, leprosy, cirrhosis of the liver and acute hepatitis. PMID- 4202882 TI - Simian model for the evaluation of immunity to influenza. AB - Rhesus monkeys (Macaca mulatta) exposed to small-particle aerosols of the Aichi strain of type A2 influenza virus responded by shedding virus from the nasopharynx for 7 to 9 days and by seroconversion (hemagglutination inhibition) 8 or 9 days after exposure. After rechallenge with the homologous virus, no replication of the organism was observed, and a serological anamnestic reaction occurred. The data indicate that the rhesus monkey is a useful primate model for evaluating induced immunity to influenza virus infection. PMID- 4202883 TI - Purification and characterization of Pseudomonas aeruginosa exotoxin. AB - A trypsin-sensitive, heat-labile exotoxin of Pseudomonas aeruginosa strain P-A 103 has been purified by a procedure that includes membrane ultrafiltration, hydroxylapatite chromatography, ion-exchange cellulose chromatography, and gel filtration chromatography. The procedure resulted in the recovery of 48% of the exotoxin with a 40-fold increase in specific activity (micrograms of protein per median lethal dose [LD(50)]). The mean lethal dose of the purified toxin administered intravenously into mice weighing 20 g was approximately 6 mug of protein. The toxin contained virtually no nucleic acid, detectable pigment, or lipopolysaccharide. When subjected to sodium dodecyl sulfate polyacrylamide gel electrophoresis, the toxin separated into at least six protein components which appeared to have similar molecular weights. The estimated molecular weight of the toxin is 54,000, and its isoelectric point is 5.0 PMID- 4202884 TI - Effects of antithymocyte sera and antimacrophage sera on cell-mediated immune reactions in Listeria-infected mice. AB - The cell-mediated immune responses of allograft rejection, delayed hypersensitivity, and resistance to Listeria monocytogenes were suppressed by injections of antithymocyte serum (ATS), but the immune responses were not significantly altered by antimacrophage serum (AMS) or normal rabbit serum (NRS). Antisera were prepared in rabbits against purified mouse thymocytes and purified peritoneal macrophages. When mice were injected with ATS near the time of skin grafting, allografts survived significantly longer. Similar administration of AMS or NRS failed to alter the course of graft rejection. Decreased footpad swelling indicated the suppression of delayed hypersensitivity in mice injected with ATS 6 days after a sublethal inoculation of Listeria cells. None of the serum treatments affected the ultimate survival of mice infected with a small number of bacteria. Either ATS or NRS was injected into immunized mice 1 day before and 2 days after a challenge inoculation of Listeria cells. Pronounced suppression of delayed hypersensitivity was found in the ATS-treated groups, along with extensive mortalities that reached 100% in the group receiving the largest dose of ATS. All control animals survived and demonstrated strong delayed hypersensitivity reactions. Antimacrophage serum had no significant effect on the three mechanisms of cell-mediated immunity that were tested. The lymphoid cells which mediate delayed hypersensitivity, antimicrobial cellular immunity, and allograft rejection possess antigenic determinants in common with thymocytes. PMID- 4202885 TI - Isolation of a specific enhancer for echovirus 6 from uninfected permissive host cells. AB - A specific enhancer for the m+ variant of echovirus 6 was isolated from uninfected, permissive host cells. The enhancer transferred the susceptibility to virus infection from permissive cells to less susceptible cells. Enhancer activity in cultured, human cells (WISH) was released by these cells into extracellular fluids at a linear rate. Maximal enhancer activity was recovered from cell monolayers that were extracted with buffered salt solutions (pH 6.6) for 5 h at 37 C. Crude enhancer preparations contained substances that reduced virus titers in permissive host cells and suppressed some of the enhancer activity. Viral inhibitory activity was removed from cellular extracts by either differential centrifugation or ion exchange chromatography. The enhancer, in contrast to inhibitory substances, remained in supernatant fractions after centrifugation at 110,000 x g for 4 h and adsorbed to diethylaminoethyl-Sephadex columns. Enhancer preparations that were devoid of inhibitory activity increased the virus titers in less susceptible simian cell cultures (approximately 100 fold) to the titers attained by fully permissive human cell cultures. A direct relationship between protein concentration and enhancer activity in cellular extracts was demonstrated. Partial purification of the enhancer by differential centrifugation and ammonium sulfate precipitation increased the specific activity of enhancer (units/mg of protein) by 13-fold. PMID- 4202886 TI - Lipids of putative relevance to virulence in Mycobacterium tuberculosis: correlation of virulence with elaboration of sulfatides and strongly acidic lipids. AB - From examination of some 40 patient strains of Mycobacterium tuberculosis, a statistically very significant correlation (Spearman's rho) can be drawn between the root index of virulence for the guinea pig (D. A. Mitchison) and the ability of the individual strains to elaborate strongly acidic lipids (SAL) in culture. These include both sulfatides (SL) and phospholipids (PL). Since essentially all, if indeed not all, of the virulent and only few attenuated strains are prolific in elaborating SAL, this criterion may be a necessary requirement for the expression of virulence in M. tuberculosis. Tested by chi-square, this premise is seen to be statistically and pragmatically highly significant. We speculate that SL may contribute to the pathogenesis of tuberculosis because of a demonstrable activity directed against host liver mitochondrial membranes (manuscript in preparation) and its synergistic potentiation of the specific toxicity of trehalose dimycolate (cord factor). The activity may also be expressed against phagosomal and lysosomal membranes within macrophages. Because of their strongly anionic character, SL and PL may interact with cationic sites on lysosomal hydrolases with resultant immobilization and/or inactivation of the enzymes. By a similar mechanism, these ionic lipids may alter the activity of bactericidal basic proteins, previously recognized in the lysosomal armamentarium. Since a minor but significant fraction of demonstrably attenuated strains is nevertheless prolific in SL or SAL elaboration, this facility alone is evidently not a sufficient criterion for expression of virulence. PMID- 4202888 TI - Release of beta-lysin from platelets by thrombin and by a factor produced in heparinized blood. AB - Removal of calcium by either citrate, oxalate, or ethylenediaminetetraacetate inhibited coagulation of blood at an early stage and prevented the release of beta-lysin from platelets. In contrast, heparin caused platelet agglutination and stimulated beta-lysin release in vitro and in vivo. This release was calcium dependent and may have been due to a calcium-dependent reaction in the blood coagulation sequence. Thrombin which by-passed the early calcium-dependent stages of coagulation directly stimulated the release of beta-lysin from platelets. However, thrombin alone or in combination with other plasma factors was not as effective in releasing beta-lysin as the regular coagulation process. Thrombin's platelet degranulating activity correlated with its beta-lysin releasing activity. In contrast to thrombin, staphylococcal coagulase, which also by-passed the calcium-dependent stages of coagulation, coagulated citrated blood without releasing beta-lysin. The release of beta-lysin has been observed previously in the absence of blood coagulation, but this is the first observation of coagulation without beta-lysin release. It is clear that beta-lysin is released from platelets during coagulation by the direct action of thrombin and that it may be released in an earlier calcium-dependent reaction. PMID- 4202887 TI - Characterization and serotyping of three feline reovirus isolates. AB - Three feline virus isolates were shown to be members of the reovirus group by their growth characteristics in cell cultures, physicochemical properties, and appearance under an electron microscope. Their close serological relationship to, or identity with, human reovirus type III was revealed by hemagglutination, hemagglutination inhibition, serum neutralization, and gel diffusion tests. One feline isolate (636) was pathogenic for suckling mice. PMID- 4202889 TI - Action of group A streptococcus extracellular product(s) on the connective tissue of the bovine heart valve. AB - Group A streptococcal strains isolated from rheumatic fever patients were cultivated in the presence of bovine heart valves in a medium devoid of components from animal origin. Other group A streptococci and various bacteria were used as controls. The supernatant of these cultures was extracted and analyzed chemically and immunologically. The extracts prepared from cultures of two "rheumatogenic" strains in the presence of bovine heart valves showed fraction(s) containing proteins, oses (neutral and amined), and uronic and sialic acids. This fraction(s) was immunologically active with both anti-group A streptococcus and antisoluble connective glycoprotein antisera, with a partial identity reaction. Experiments with a diffusion chamber and attempts to precipitate a postulated enzyme from the culture of these strains by ammonium sulfate suggest that this action is due to an extracellular product of the bacteria. The meaning of these data in the physiopathology of rheumatic cardiac lesions is briefly discussed. PMID- 4202890 TI - Role of mycobactin in the growth and virulence of tubercle bacilli. AB - Tubercle bacilli failed to grow in iron-void media enriched with solutions of iron-containing transferrin (Tr) or ferritin (F) because these substances do not provide the bacilli with iron, which is essential for their growth. Animal serum and macrophages possessed no iron carrier with an ability to satisfy the need of the bacteria for the metal. Mycobactin (M), the growth-product of tubercle bacilli, removed iron from Tr and F and supplied the metal for bacillary utilization. The role of M in the growth of tubercle bacilli was influenced by nonionic surfactants which inhibited bacillary growth by removing M from the bacillary cells and interfering with the absorption of M-iron complexes. Experiments with Tween 80, Triton WR-1339, and lecithin showed that avirulent bacilli lose M at lower concentrations of the surfactants than virulent bacilli. Since avirulent and virulent bacilli possess the same amount of M, these findings indicate that M is bound more firmly to lipid-rich virulent than lipid-poor avirulent cells. These findings indicate that the resistance of virulent bacilli to the M-removing activity of the surfactants is an indicator of their ability to multiply in the infected host and may be used as a measure of bacillary virulence. PMID- 4202891 TI - Reactivity of purified proteins and polysaccharides from Mycobacterium tuberculosis in delayed skin test and cultured lymphocyte mitogenesis assays. AB - Hypersensitivity responses to two highly purified and well characterized mycobacterial proteins and a preparation of mycobacterial arabinogalactanarabinomannan were studied by using guinea pig skin tests and in vitro-cultured human lymphocyte mitogenesis stimulation assays. The purified proteins were found to elicit delayed-type hypersensitivity skin test reactions and to stimulate mitogenesis in cultured lymphocytes. The polysaccharide preparation was found to evoke delayed skin tests but not to stimulate cultured lymphocytes. PMID- 4202893 TI - Benign intra-osseous cysts of the jaws. PMID- 4202892 TI - Antigens of Streptococcus mutans. II. Characterization of an antigen resembling a glycerol teichoic acid in walls of strain BHT. AB - Cold 10% trichloroacetic acid was used to extract antigens from purified cell walls of Streptococcus mutans BHT. Column chromatography on Biogel P-100 resolved two serologically reactive fractions (B and C). These fractions were ascertained to be relatively pure by recycling on Biogel P-100, Ouchterlony double-diffusion analysis, and immunoelectrophoresis. Fractions B and C demonstrated bands of absolute homology by double-diffusion but different mobilities by immunoelectrophoresis. Chemical analysis indicated that fraction B is a polysaccharide composed principally of rhamnose and galactose, with smaller amounts of glucose and glucosamine. Small quantities of glycerol and phosphorus also were found. Fraction C was composed mainly of galactose, glycerol, and phosphorus. Alkaline hydrolysis of this fraction yielded products typically released by the degradation of a glycerol teichoic acid, such as glycerol monophosphate, glycerol diphosphate, inorganic phosphorus, and several glycosyl glycerol phosphates. Diglycerol triphosphate was not detected. Side-group analysis revealed that glycerol was substituted by mono- and trigalactosyl moieties. Fraction C was deduced to contain 25 glycerol phosphate units per polymer length. Hapten inhibition studies revealed a beta-galactoside as the probable hapten on this antigen. The BHT teichoic acid reacted strongly with FA-1 antiserum. It showed bands of homology with both BHT and FA-1 crude acid extracts upon double-diffusion, using antisera to either strain. The BHT teichoic acid also displayed immunoelectrophoretic behavior identical to one of the mobile FA-1 cell wall antigens, again using either serum to develop precipitin bands. It is concluded this antigen may possess a serotype-specific determinant for S. mutans serotype b. PMID- 4202895 TI - A national leader observes and reflects. PMID- 4202894 TI - A survey of school dental health programs in the state of Connecticut. PMID- 4202896 TI - An immunodiffusion analysis of Mycobacterium lepraemurium Marchoux and Sorel. PMID- 4202897 TI - The serological response to Aspergillus fumigatus in experimental mycotic abortion in sheep. PMID- 4202898 TI - The sensitivity of Brucella abortus to chemotherapeutic agents. PMID- 4202899 TI - Pyocin-sensitivity testing as a means of typing Pseudomonas aeruginosa. PMID- 4202900 TI - Proceedings: The effect of tissue-culture cells in promoting prolonged survival of Neisseria gonorrhoeae in artificial subcutaneous cavities of mice. PMID- 4202901 TI - Proceedings: Corynecine typing of diphtheria bacilli. PMID- 4202902 TI - Letter: Crystallization and preliminary x-ray investigation of bovine erythrocyte carbonic anhydrase. PMID- 4202903 TI - One course Sue Barton never took: health care economics. PMID- 4202904 TI - Electrophoretic and immunological studies on the light chains of myosin. PMID- 4202905 TI - Relation between seramarcide, an antitussive for dogs and serratigen from Serratia marcescens. PMID- 4202906 TI - Electrophoretic and immunological studies on the light chains of myosin. PMID- 4202908 TI - [The treatment of hypercalcemia in infancy]. PMID- 4202909 TI - Neuroleptanalgesia in small animals. PMID- 4202910 TI - [Use of 4 antibacterial preparations in the treatment of destructive tuberculosis of the lungs]. PMID- 4202911 TI - [Antigenic structure of acid-fast Mycobacteria isolated from patients with tuberculosis]. PMID- 4202912 TI - [Apparatus for receiving of the bronchial lavage water in tuberculosis patients]. PMID- 4202913 TI - Immunochemical characteristics and differentiation of Nocardiae. PMID- 4202915 TI - [Treatment of psoriasis]. PMID- 4202914 TI - [Influence of culture conditions on the biosynthesis of alpha tocopherol in Euglena gracilis]. PMID- 4202916 TI - Circulatory effects of splenectomy in the horse. I. Effect on red-cell distribution and variability of haematocrit in the peripheral blood. PMID- 4202917 TI - Circulatory effects of splenectomy in the horse. II. Effect on plasma volume and total and circulating red-cell volume. PMID- 4202918 TI - [Rare heart abnormalities in a male cat. Contribution to the Taussig-Bing complex]. PMID- 4202919 TI - Experiments on the hepato-oesophageal artery of the mouse. PMID- 4202920 TI - [Catalase activity in the blood of suckling piglets and fattening calves with insufficient blood supply]. PMID- 4202921 TI - [Effect of whole body Roentgen irradiation and of 2,4,6-triethylenimino-1,3,5 triazin on the mouse kidney: induction of a deoxyribonuclease I]. PMID- 4202922 TI - Intra-abdominal pressure in small ruminants. PMID- 4202923 TI - [Structure of villi in the porcine small intestine. Stereo microscopy findings]. PMID- 4202924 TI - [Primary ossification of the lateral meniscus (author's transl)]. PMID- 4202925 TI - Differences in the autoradiographic localization of labelled morphine-like analgesics in the mouse. PMID- 4202926 TI - Effect of contractions in vitro on glycogen content and glycogen synthetase activity in muscle. PMID- 4202927 TI - Effects of insulin and testosterone on glycogen synthesis and glycogen synthetase activity in rat levator ani muscle. PMID- 4202928 TI - The effect of insulin on epinephrine and glucagon inactivated glycogen synthetase I in the isolated perfused rat liver. PMID- 4202929 TI - [Histological study of organs of experimental animals treated with beromycin]. PMID- 4202930 TI - [Sensitivity of human tumor cells in culture to mitomycin C and thiophosphamide]. PMID- 4202931 TI - [Effect of chymotrypsin and chymopsin on penicillin distribution in the organism]. PMID- 4202932 TI - [Effect of donor species specificity on the antibiotic activity in studies with human and animal blood sera]. PMID- 4202934 TI - Influence of formaldehyde-treated casein supplements on the concentration of epsilon-N-methyllysine in sheep plasma. PMID- 4202933 TI - Nitrogen fixation by Anabaena cylindrica. II. Nitrogenase activity during induction and aging of batch cultures. PMID- 4202936 TI - Studies on goat anti-CBA thymocyte globulin: the large scale preparation, purification and testing of anti-lymphocyte serum and anti-lymphocyte globulin. PMID- 4202935 TI - The role in chylomicron formation of phospholipase activity of intestinal Golgi membranes. PMID- 4202937 TI - Air-blast avoidance learning sets in protein-malnourished monkeys. PMID- 4202938 TI - The visual fields of the frog and toad: a comparative study. PMID- 4202939 TI - The occurrence of two types of synthesis of deoxyribonucleic acid during normal growth in Bacillus subtilis. AB - A study of the relative utilization of thymine and thymidine as precursors for DNA synthesis during normal growth in Bacillus subtilis showed that thymine serves preferentially as a precursor for ;repair' synthesis, whereas thymidine is used preferentially for ;replicative' synthesis. Further, evidence was obtained which suggests that during normal growth both ;replicative' and ;repair' DNA syntheses occur simultaneously. ;Repair' synthesis is distinguished not only on the basis of its preferential utilization of thymine but also by its selective inhibition by caffeine. ;Replicative' synthesis, however, is selectively inhibited by 6-(p-hydroxyphenylazo)-uracil. ;Repair' synthesis would seem to be a ;pre-fork' phenomenon and its inhibition is highly lethal to the cell. PMID- 4202940 TI - The structure of a polymer containing galactosamine from walls of Bacillus subtilis 168. AB - Cell walls of Bacillus subtilis 168 contain a phosphorylated polysaccharide composed of N-acetylgalactosamine, glucose and phosphate. Controlled acid hydrolysis gives 3-O-beta-d-glucopyranosyl-N-acetylgalactosamine with a phosphomonoester group at the 6-position of glucose. It is likely that the polysaccharide consists of disaccharide units connected by phosphodiester residues joining the 1-position of N-acetylgalactosamine to the 6-position of glucose in the neighbouring unit. PMID- 4202941 TI - A teaching course in general practice. PMID- 4202942 TI - Interocular transfer in split-brain monkeys following serial disconnection. PMID- 4202943 TI - Cold fiber heat sensitivity: dependency of "paradoxical" discharge on body temperature. PMID- 4202944 TI - [Suggestions for the preparation and testing of radiopharmaceutical agents]. PMID- 4202945 TI - Selective removal of albumin from plasma by affinity chromatography. PMID- 4202946 TI - Immune responses in congenitally thymus-less mice. II. Quantitative studies of serum immunoglobulins, the antibody response to sheep erythrocytes, and the effect of thymus allografting. PMID- 4202947 TI - Cell-mediated immune response in malnutrition. PMID- 4202948 TI - Universal occurrence of antibodies to tubercle bacilli in sera from non tuberculous and tuberculous individuals. PMID- 4202949 TI - Rosetting of human red blood cells to thymocytes and thymus-derived cells. PMID- 4202950 TI - Inhibition of IgG complex-induced platelet aggregation by antiglobulin-active cryoglobulin IgM components. PMID- 4202951 TI - Antigenic changes in transformed FL human amnion cells. PMID- 4202952 TI - Sensitivity of non-human cells to human lymphocyte 'proliferation inhibitory factor' (PIF) in vitro. PMID- 4202953 TI - Drosophila salivary chromosomes as test system for antinuclear antibody assay. PMID- 4202954 TI - Immunochemical studies of four human IgM pyroglobulins. PMID- 4202955 TI - Further studies on the C3b inactivator or conglutinogen activating factor (KAF). PMID- 4202957 TI - Comparison of the capillary tube and explant methods for the in vitro assay of tuberculin. AB - Purified antigens prepared from mycobacteria were tested for nonspecific toxicity and tuberculin activity by two in vitro methods. One technique utilized measurements of macrophage migration in 4-day-old cultures of spleen from normal and tuberculin-sensitive rabbits. The other method was a modification of the capillary tube technique. To obtain enough peritoneal macrophages for good quantitation, changes were made in the method of harvesting cells, and in some instances exudates from two or more Wright strain no. 13 guinea pigs were combined. The capillary tube method was as sensitive as the explant method for detecting nonspecific toxicity. Each tuberculin assay included a group of control cultures of cells from sensitive animals, test groups containing two widely spaced concentrations of a standard tuberculin, PPD-S, and one or more concentration of the tuberculin to be tested. Macrophages from tuberculin sensitive animals were regularly inhibited by 0.25 mug of PPD-S per ml with both in vitro methods. The potency of the test tuberculins relative to that of PPD-S was somewhat greater in capillary tube assays than in explant cultures. A purified tuberculopolysaccharide was equally inhibitory for both normal and tuberculin-sensitive cells in both culture systems. PMID- 4202956 TI - Quantitative chemical composition of peptidoglycan of Listeria monocytogenes. AB - The qualitative and quantitative chemical composition of the peptidoglycan layer of Listeria monocytogenes cell walls was determined. The peptidoglycan layer was isolated from intact cells after treatment with sodium lauryl sulfate and digestion with Pronase. The isolated peptidoglycan contained carbohydrates which included hexose, rhamnose, and amino sugars. The amino sugar was identified as glucosamine which was present in very high micromole concentration, as compared with the amino acids, muramic acid, or diaminopimelic acid. In addition, protein and phosphorus were also present. However, the presence of teichoic acid was not detected in the peptidoglycan. Protein moiety contained a total of 18 amino acids with lysine as the N-terminal amino acid. PMID- 4202958 TI - Extracellular antigens from Listeria monocytogenes. II. Cytotoxicity of hemolytic and lipolytic antigens of Listeria for cultured mouse macrophages. AB - Purified preparations of hemolytic and lipolytic antigens were shown to be cytotoxic for tissue cultures of mouse peritoneal macrophage monolayers. The percent reduction in viability was proportional to the concentration of antigen used although, for a brief period, the hemolytic antigen stimulated the growth of cultured macrophages. Hemolytic and lipolytic antigens were synthesized by an hemolysin-producing strain (7973), but were deficient or totally lacking in nonhemolysin-producing strains (9037-7, 4219). The inoculation of strain 7973 onto macrophage monolayers at a bacterium to macrophage ratio of 10:1 resulted in a complete loss of viable phagocytic cells. The decrease in viable phagocytic cells was accompanied by an increase in viable listeria. Pronounced cytopathic activity with proliferation of listeria was also observed when 200 U of lipolytic antigen were added to macrophage monolayers that had been infected with the smooth type nonhemolysin-producing strain (4219) on the previous day. On the other hand, a high percentage of macrophages survived when exposed to nonhemolysin-producing strains only. In this case, listeria were not recovered by routine culture methods. The data presented do not establish that phagocytic cell destruction with accompanying microbial proliferation is the direct result of hemolysin elaboration; however, they suggest that there is need for further exploration of the role of the hemolysin in listeriosis. PMID- 4202959 TI - Enzyme-linked immunosorbent assays for cholera serology. AB - The enzyme-linked immunosorbent assay (ELISA) principle of Engvall and Perlmann, which employs antigen-coated tubes and enzyme-labeled anti-immunoglobulins, was elaborated for use in cholera serology. Immunoglobulin class-specific determinations of primary binding titers of antibodies to cholera exotoxin and endotoxin were more sensitive than were neutralization and vibriocidal tests. It was notable that rather high ELISA titers of immunoglobulin M (IgM) antibodies to exotoxin, which lacked neutralizing capacity were registered, whereas corresponding levels of immunoglobulin G (IgG) antibodies were effectively neutralizing. A modified technique permitting measurement of the binding rate of antibody to the solid-phase antigen was introduced as a possible tool for antibody avidity estimation. Such measurements indicated a wide avidity difference between the IgG and the IgM anti-exotoxin antibodies, which could explain their different neutralizing capacities. The observation that increasing binding rate of the IgG antibodies during the course of the primary immune response could compensate for decreasing antibody amount with regard to neutralizing capacity of serum also indicated the importance of antibody avidity for toxin neutralization. Inhibition with soluble antigen permitted quantitative determination of antigen; levels of exotoxin 0.09 mug/ml and of endotoxin to 1.3 mug/ml were measured. PMID- 4202960 TI - Comparison of strains of BCG. I. Antigenic analysis and tuberculin reactivity. AB - At least 10 of 11 demonstrable antigens in unheated culture filtrates of 12 vaccine strains of BCG were shared as determined in a reference antigen-antibody immunoelectrophoresis system. Filtrates from each of the BCG strains gave equivalent skin test reactions in homologously and heterologously sensitized guinea pigs. By these immunological parameters, the 12 BCG strains were remarkably similar. PMID- 4202961 TI - Experimental induction of anergy to coccidioidin by antigens of Coccidioides immitis. AB - Failure to react to coccidioidin (anergy) often occurs in patients with disseminated coccidioidomycosis. One possible reason may be desensitization by excessive amounts of antigen. This was studied experimentally by injection of soluble and hyphal antigens of Coccidioides immitis into coccidioidin- and tuberculin-sensitive guinea pigs. Guinea pigs sensitized by injection of killed hyphal cells of C. immitis in complete Freund adjuvant were subsequently injected daily either with soluble coccidioidal antigen administered intraperitoneally or with hyphal antigen administered either subcutaneously or intraperitoneally. Gradual loss of cutaneous reactivity to coccidioidin occurred, but the reactivity to tuberculin remained unimpaired. The rapidity of desensitization was roughly proportional to the dose of antigen with desensitization occurring as early as 6 days after beginning injections. This anergic state was temporary, and reactivity returned several days after discontinuing injection of antigen. Injection of coccidioidal antigen led to production of coccidioidal complement-fixing antibody, but there was no consistent relationship between the antibody titer and state of cutaneous reactivity to coccidioidin. Peritoneal exudate or pulmonary alveolar cells from desensitized animals migrated freely in the presence of coccidioidin but were inhibited in the presence of tuberculin. Heat treatment did not impair the capacity of the soluble or hyphal antigen to induce anergy, thus suggesting that the antigen active in complement fixation was perhaps not involved in desensitization. Polysaccharide obtained by ethanol precipitation of dialyzed coccidioidin failed to induce anergy. Dialysis of the soluble coccidioidal antigen caused the loss of the desensitizing activity. Thus, specific desensitization could be induced by administration of large doses of coccidioidal antigen but dialyzable components appear important in this desensitization. PMID- 4202962 TI - Thermography of tuberculin reactions in cattle. AB - The allergic reactions of dermal induration and hyperthermia were compared in tuberculin-hypersensitive calves. Tuberculins prepared from Mycobacterium avium, M. bovis, and M. paratuberculosis were administered intradermally and the responses were compared. The indurations from immediate and delayed hypersensitivity reactions were readily distinguishable, but the hyperthermic responses appeared to contain elements of both immediate and delayed hypersensitivity. PMID- 4202965 TI - Diffusion artifacts in cytochemistry of catalase. PMID- 4202963 TI - Cytological localization of Dengue-2 antigens: an immunological study with ultrastructural correlation. AB - Immunofluorescence and electron microscopy were used to study the development and cytological distribution of dengue-2 virion and nonvirion antigens in monkey kidney cells. The type and combination of fixatives were found to affect the intensity of fluorescence. Paraformaldehyde fixation alone resulted in a low level of fluorescence, but an additional fixation step with ethanol or acetone resulted in maximum staining. No fluorescence was obtained after fixation with glutaraldehyde alone or in combination with other solvents. Methanol caused selective ablation of fluorescence by antibody to purified virions. Dengue specific fluorescence that was most intense in the perinuclear area radiated in a granular pattern of decreasing intensity into the cytoplasm. The perinuclear fluorescence was associated with nonvirion antigens and the cytoplasmic fluorescence was associated with virion antigens. Electron micrographs of infected cells revealed vesicular bodies with reticular electron-dense centers, clusters of structurally complete virions deep within the endoplasmic reticulum, and single virus particles in vacuoles near the periphery of the cell. PMID- 4202964 TI - Possible transmission of serum (Australia-antigen-positive) hepatitis via the conjunctiva. AB - A nursing sister developed Australia-antigen-positive hepatitis 101 days after the blood of an Australia-antigen-positive patient was accidentally introduced into her eye. There may be important implications for those caring for patients with Australia-antigenemia or undertaking laboratory investigations on their blood. PMID- 4202967 TI - A steady state model of sequential irreversible enzyme reactions. PMID- 4202966 TI - [Acitivity of physiological inhibitors of blood coagulation and fibrinolysis during pregnancy, labor, and in the puerperium. Immunological studies]. PMID- 4202968 TI - Malnutrition and hepatitis-associated antigen infection. PMID- 4202969 TI - Infantile malnutrition and malabsorption. PMID- 4202970 TI - Visual discordance cues induce prism adaptation in normal monkeys. PMID- 4202971 TI - [Keratitis caused by Pseudomona aeruginosa in comatose patients]. PMID- 4202972 TI - [Prolactin (PRL) secretion during the normal menstrual cycle]. PMID- 4202973 TI - [Chagas' disease. Report of a clinical case]. PMID- 4202975 TI - [Wound healing in the palatal mucosa. A commentary]. PMID- 4202974 TI - White blood cell acid hydrolases in leukaemias, mucopolysaccharidoses and mannosidosis. PMID- 4202976 TI - [Spectrophotometric and serologic diagnosis of fetal distress in pregnant women with Rh immunization]. PMID- 4202977 TI - [Incidence of marriages with ABO and RhO incompatibility in Plovdiv]. PMID- 4202978 TI - Maternal protein deprivation and toxemia of pregnancy: studies in the rhesus monkey (Macaca mulatta). PMID- 4202979 TI - Prolactin secretion in sixty-five patients with galactorrhea. PMID- 4202980 TI - Thiol solutions--inhibition of autoxidation. PMID- 4202981 TI - Simplified methods for automated ion-exchange separation of peptides and accelerated manual Edman degradations. PMID- 4202982 TI - A spectrophotometric assay for Drosophila dopa decarboxylase. PMID- 4202983 TI - Comparative effects of dihydroergotamine and hydergin on the blood flow, capillary filtration rate and the capacitance vessels in the human calf studied by plethysmography. PMID- 4202984 TI - Juvenile xanthogranuloma in a patient with Niemann-Pick disease. PMID- 4202985 TI - [Comments on the treatment of syndesmosis-rupture of the ankle (author's transl)]. PMID- 4202986 TI - [Differential blood counts with EDTA blood (author's transl)]. PMID- 4202987 TI - The relationship between progestins and gonadotropins during the late luteal phase of the menstrual cycle in rhesus monkeys. PMID- 4202988 TI - Thyrotropin-releasing hormone in the hypothalamus of the rat. PMID- 4202989 TI - Sexual maturation in the female rhesus monkey and the development of estrogen induced gonadotropic hormone release. PMID- 4202990 TI - Osmotic stimulation of vasotocin secretion by the toad's hypothalamo neurohypophyseal system in vitro. PMID- 4202991 TI - Immunological techniques. PMID- 4202993 TI - Effect of L-asparagine on growth of Mycobacterium tuberculosis and on utilization of other amino acids. AB - l-Asparagine controls the utilization of other amino acids by Mycobacterium tuberculosis (H37Ra) in aerated, liquid synthetic media. In a mixture containing asparagine and either l-alanine or l-glutamic acid, amino acid utilization is diphasic, with asparagine being utilized first. Short-term growth rates and cell yields are diminished and mimic those seen with asparagine alone. Catabolite repression is the probable regulatory mechanism responsible for this effect of asparagine. In contrast, in the presence of aspartic acid, asparagine stimulates growth and increases utilization of aspartic acid. PMID- 4202992 TI - Absence of 3'-terminal residues from transfer ribonucleic acid of dormant spores of Bacillus megaterium. AB - Essentially all (>97%) of the transfer ribonucleic acid (tRNA) in log-phase and sporulating cells of Bacillus megaterium contains a complete 3'-cytidyl-cytidyl adenosine terminus. However, about one-third of the tRNA in the dormant spore lacks the 3'-terminal adenosine 5'-monophosphate (AMP) residue, and some of the adjacent cytosine monophosphate residues are also missing. Examination of specific tRNAs indicated that those specific for isoleucine, leucine, and methionine are missing 30 to 40% of their terminal residue, whereas tRNAs specific for tyrosine lack 88% of the 3'-terminal AMP. Defective spore tRNA is not degraded during germination, but the missing residues are added back in the first minutes of the process. The enzyme catalyzing the addition reaction, tRNA nucleotidyltransferase, is present in the dormant spore at a level similar to that found in the vegetative cell. PMID- 4202994 TI - Effect of helium gas at elevated pressure on iron transport and growth of Escherichia coli. AB - Helium at an ambient pressure of 68 at m with 0.2 atm of O(2) shortened by 1 to 1.5 h the lag phase for growth of Escherichia coli in minimal medium supplemented with 2 muliters of cell-free culture filtrate (CFF) per ml or with 1 muM 2,3 dihydroxybenzoylserine (DHBS), an iron chelator. The lag phase of cultures not exposed to helium could be shortened by use of supplements, but higher concentrations were required-10 to 30 muliters of CFF per ml or 10 to 50 muM DHBS. Strain AN 193 of E. coli, which requires the DHBS precursor 2,3 dihydroxybenzoic acid (DHBA), grew well in media with 10 muM DHBA when exposed to helium at 68 atm, whereas 100 muM DHBA was required for growth in unexposed cultures. In the presence of 100 muM DHBA plus 1.0 muM ethylenediaminetetraactic acid, growth was inhibited at 1 and 68 atm. Growth was restored, however, by the addition of 0.1 muM FeSO(4) at 68 atm and 1.0 muM FeSO(4) at 1 atm, but lag times were invariably shorter in the pressurized cultures. Hydrostatic pressures of 68 atm did not reduce the lag phase in the presence of CFF, DHBS, or DHBA. Our results suggest that 68 atm of helium pressure, but not hydrostatic pressure, elicited a more rapid transport of iron into the cells. PMID- 4202995 TI - Characterization of three plasmid deoxyribonucleic acid molecules in a strain of Streptococcus faecalis: identification of a plasmid determining erythromycin resistance. AB - Three plasmids designated alpha, beta, and gamma, distinguishable by their molecular weights (6, 17, and 34 million, respectively) were isolated from Streptococcus faecalis strain DS-5 (ATCC 14508). Derivatives of this strain "cured" for erythromycin resistance lacked the beta-plasmid. In the parent strain the beta-plasmid was estimated to be present to the extent of one to two copies per chromosomal genome equivalent whereas the alpha- and gamma-plasmids were about nine and five copies, respectively. PMID- 4202996 TI - Ultrastructural and chemical alteration of the cell envelope of Pseudomonas aeruginosa, associated with resistance to ethylenediaminetetraacetate resulting from growth in a Mg2+-deficient medium. AB - Cells of Pseudomonas aeruginosa became resistant to the lytic effect of ethylenediametetraacetate (EDTA) when grown in a Mg(2+)-deficient medium. To correlate ultrastructural changes in the cell wall associated with the shift to EDTA-resistance, a freeze-etch study was performed. Upon fracturing, the outer cell wall membrane split down the hydrophobic center to reveal the outer (concave) and inner (convex) layers. The concave cell wall layer of EDTA sensitive cells grown in Mg(2+)-sufficient medium contained spherical units resting on an underlying smooth support layer. Upon EDTA treatment, approximately one-half of these spherical units were extracted. Cells grown in Mg(2+)-deficient medium were resistant to EDTA. The concave cell wall layer of EDTA-resistant cells had increased numbers of highly compacted spherical units, giving this layer a disorganized appearance. The highly compacted appearance of this layer was unaltered by EDTA treatment. Thus, growth in Mg(2+)-deficient medium resulted in cells which were resistant to EDTA and which possessed an ultrastructurally altered outer layer of the outer cell wall membrane. Cell envelopes from EDTA resistant cells were found to possess 18% less phosphorus, 16.4% more total carbohydrate, and 13.3% more 2-keto-3-deoxyoctonate than cell envelopes from EDTA sensitive cells. There were also qualitative, but not quantitative, differences in the protein content of cell envelopes from EDTA-resistant and EDTA-sensitive cells. PMID- 4202997 TI - Phenotype recognition of pyocyanine mutants in pseudomonas aeruginosa. AB - Certain classes of pyocyanine mutants in Pseudomonas aeruginosa escape detection when screened in the presence of wild-type or other mutant cells. A technique is described for recognizing mutant phenotypes after cells are in individual agar wells. The procedure eliminates cross-feeding phenomena as well as the masking of mutant phenotypes by diffusing pyocyanine produced by nearby clones. PMID- 4202998 TI - Mapping of the 5-methyltryptophan resistance locus in Bacillus subtilis. AB - The 5-methyltryptophan resistance locus (mtr) in Bacillus subtilis, which leads to constitutive production of the tryptophan enzymes, has been mapped on the chromosome. The order of loci is ser-1-mtr-aroF-aroB-trp-hisB. PMID- 4202999 TI - Changes in menaquinone concentration during growth and early sporulation in Bacillus subtilis. AB - In two strains of Bacillus subtilis, menaquinone-7 has been shown to reach maximal cellular concentrations during early stationary phase. These concentration changes closely parallel the previously reported concentration changes in the cytochromes. PMID- 4203001 TI - Pneumothorax complicating continuous ventilatory support. PMID- 4203002 TI - [Formularization of the quantity and distribution of radioisotopes in the human body]. PMID- 4203000 TI - Characterization of the antigenic subunits of the envelope protein of Yersinia pestis. AB - Chemical, physical, and immunological properties of the envelope antigen of Yersinia pestis strains have been investigated. The antigen consists of two components with isoelectric points (pI) of 4.6 and 4.8. One component (pI 4.6) is a protein bound to a small carbohydrate moiety identified as an oligomeric galactan; the other component (pI 4.8) is a simple protein. These two components are antigenically identical. In buffered solution, the antigen exists as aggregates of molecular weights larger than 300,000. The aggregates dissociate into a variety of smaller molecular weight forms depending on the nature of the treatment for dissociation. Each aggregate can be further dissociated into a single antigenic subunit fraction containing protein and glycoprotein species with molecular weights in the range from 15,000 to 17,000. The subunits can be obtained by a dissociation treatment with 0.1% mercaptoethanol in 0.25% sodium dodecyl sulfate at 95 C for 5 min. The subunits will readily reaggregate into a variety of larger molecular weight forms on the removal of dodecyl sulfate. PMID- 4203003 TI - [Bone scintigrams of the aged patients. 2. Accelerated bone metabolism in the affected legs in femoral neck fractures]. PMID- 4203004 TI - Some quantitative aspects of in vitro thyroid diagnostic tests. PMID- 4203005 TI - [Certain indicators of hemocoagulation and their clinical value in typhoid paratyphoid diseases]. PMID- 4203006 TI - Occult blood detection in faeces of various animal species. PMID- 4203008 TI - Letter: Statistical analysis of treatment with vitamin E. PMID- 4203007 TI - Impaired lymphocyte function in untreated Hodgkin's disease. PMID- 4203009 TI - Treatment of disseminated gonococcal infection. A prospective evaluation of short term antibiotic therapy. PMID- 4203010 TI - Letter: Urinary sphingomyelin in Niemann-Pick disease. PMID- 4203011 TI - Letter: Chagas's disease--another hazard in acute leukemia. PMID- 4203012 TI - Survival of common bacteria in liquid culture under carbon dioxide at high temperatures. PMID- 4203013 TI - Understanding cerebrovascular function. Contributions of space techniques. PMID- 4203014 TI - Microbial flora found in the products of conception in spontaneous abortions. PMID- 4203015 TI - Blood disappearance rates of certain hormones and enzymes advocated as fetoplacental function tests. PMID- 4203016 TI - Congenital tuberculosis. PMID- 4203017 TI - Proceedings: Medullary carcinoma of the thyroid gland. PMID- 4203018 TI - Proceedings: The role of radiation therapy in the management of patients with carcinoma of the rectum and rectosigmoid. PMID- 4203020 TI - Proceedings: The cost of cancer. PMID- 4203019 TI - Proceedings: Megavoltage irradiation for bladder cancer: alone, postoperative, or preoperative? PMID- 4203021 TI - Proceedings: The role of radiation therapy in the treatment of soft-tissue sarcoma in adults. PMID- 4203022 TI - Neurons in rhesus monkey visual cortex: systematic relation between time of origin and eventual disposition. AB - Autoradiographic evidence after injection of tritiated thymidine indicates that cell position in the laminae of the monkey visual cortex is systematically related to time of cell orgin. The earliest-formed neurons, destined for the deepest stratum, arise at about embryonic day 45, and the last ones, destined for the outermost cell stratum, form at about day 102; cells of intervening layers are generated at intervening times. No neocortical neurons are produced in the last two prenatal months or after birth. Compared to cortical neurons in rodents, those in the monkey arise earlier, and the "inside-out" relation of cell position to time of origin is more rigid. PMID- 4203023 TI - Deuterium oxide effect on temperature-dependent survival in populations of Drosophila melanogaster. AB - A comparison of the mean life-spans for populations of Drosophila melanogaster at 10 degrees , 20 degrees , 25 degrees , and 30 degrees C maintained on media prepared with distilled water and with 50 percent deuterium oxide shows that deuteration decreases longevity at all four temperatures. The magnitude of the difference between the mean survival times of populations maintained on deuterated and nondeuterated media is inversely related to temperature between 10 degrees and 30 degrees C. PMID- 4203024 TI - Carbonic anhydrase and osteoclasts: localization by labeled inhibitor autoradiography. AB - Autoradiography with tritiated acetazolamide indicates that osteoclasts of the hen and chick contain concentrations of carbonic anhydrase which are similar to those in pancreatic acinar cells. Grain counts of osteoblasts and osteocytes were not different from background. Thus, a sufficient quantity of carbonic anhydrase seems to be present in osteoclasts to be of physiological importance in bone resorption. PMID- 4203025 TI - Calcium ion release in mechanically disrupted heart cells. AB - In cardiac muscle fibers which have had their sarcolemma disrupted intracellular stores of calcium ions can be released by the same chemical stimuli which cause their release from the sarcoplasmic reticulum of skinned skeletal muscle fibers. These stimuli are increases in calcium or caffeine concentrations and substitution of chloride for propionate or sodium for potassium in solutions bathing the fibers. PMID- 4203026 TI - Management of the nephrotic syndrome. PMID- 4203027 TI - Acute stroke management and patient outcome: the value of Neurovascular Care Units (NCU). PMID- 4203028 TI - Salivatory fibres in the trigeminal part of the lingual nerve to the mandibular salivary gland of the monkey. PMID- 4203029 TI - A new approach to the synthesis of oligodeoxyribonucleotides. PMID- 4203030 TI - Evaluation of heterologous vascular grafts as small vessel substitutes. PMID- 4203031 TI - Physical measurements of medical electron beams--a review. PMID- 4203032 TI - Fibroblast surface antigen: a new serum protein. PMID- 4203033 TI - Neuronal migration, with special reference to developing human brain: a review. PMID- 4203034 TI - Studies on the control of some simple motor tasks. 3. Comparison of the EMG pattern during ballistically initiated movements in man and squirrel monkey. PMID- 4203035 TI - Studies on the control of some simple motor tasks. IV. Relation between parameters of motion and motor output in squirrel monkey. PMID- 4203036 TI - Responses of small myelinated "warm" fibers to noxious heat stimuli applied to the monkey's face. PMID- 4203037 TI - Visual discrimination deficits associated with posterior inferotemporal lesions in the monkey. PMID- 4203038 TI - Operable breast cancer: the case against conservative surgery. PMID- 4203039 TI - Operable breast cancer: in defense of conservative surgery. PMID- 4203040 TI - Features suggesting curability in lymphoma and leukemia. PMID- 4203041 TI - Colon and rectal lesions: a tutorendoscopic view. PMID- 4203042 TI - [Sucker type locator for intraocular foreign bodies and clinical use of localizing register charts]. PMID- 4203043 TI - [Differential diagnosis of unilateral exophthalmos by ultrasonography]. PMID- 4203044 TI - [Preliminary observation on cryosurgery in retinal detachment cryosurgery]. PMID- 4203045 TI - [A cryosurgical instrument--a cold knife and its clinical use in otorhinolaryngology]. PMID- 4203046 TI - [Clinical and immunologic observation on 2 lines of attenuated measles vaccine virus on passage in chick embryo tissue culture]. PMID- 4203047 TI - [Pulmonary encephalopathy and some therapeutic problems]. PMID- 4203048 TI - [Prevention and treatment of leakage of esophagogastric anastomosis following resection of carcinoma of the esophagus and gastric cardia]. PMID- 4203049 TI - [Review on the management of extensive 3d degree burns]. PMID- 4203050 TI - [Malignant reticulosis: report of 11 cases]. PMID- 4203051 TI - [Surgical treatment of thromboangiitis obliterans with lumbar sympathectomy and partial adrenalectomy]. PMID- 4203052 TI - [Combined Chinese-Western therapy for tetanus: analysis of 217 cases]. PMID- 4203053 TI - [Puerperal mastitis treated with Fructus gleditsiae: report of 43 cases]. PMID- 4203054 TI - [Orethral diverticulum in women: report of 9 cases]. PMID- 4203055 TI - [Stevens-Johnson syndrome: report of 4 cases]. PMID- 4203056 TI - [Adult spirometra mansoni infection, a case report]. PMID- 4203057 TI - [Successful treatment of postpartum hypopituitarism with decoction of Radix glycyrrhizae and Radix ginseng: report of a case]. PMID- 4203058 TI - [Application of lasers in ophthalmology]. PMID- 4203059 TI - [Clinicopathological conference. No. 9. Fever, chest pain, cough, acute asthma, cyanosis, profuse sweating and the increased pulse rate]. PMID- 4203060 TI - Phenotypic variation in the popliteal pterygium syndrome. PMID- 4203061 TI - Mass screening newborns for mucopolysaccharidoses. PMID- 4203063 TI - Homogeneity of antibodies produced by clones in vitro. PMID- 4203062 TI - Assays for cellular antigens in the presence of detergents. PMID- 4203064 TI - Antibody response, measured by a plaque assay, compared to cellular response after skin allograft in mice. PMID- 4203065 TI - Carbon dioxide production from pyruvate and glucose by bovine oocytes. PMID- 4203066 TI - Protein incorporation by isolated amphibian oocytes. IV. The role of follicle cells and calcium during protein uptake. PMID- 4203067 TI - Lysosomal enzymes in relation to the isoproterenol-induced secretory cycle in rat parotid gland. PMID- 4203068 TI - Ontogeny of gamma-crystallin in the chick lens. PMID- 4203069 TI - Proceedings: Anatomy and pathophysiology of ocular circulation. PMID- 4203070 TI - Proceedings: Studies on retinal blood flow regulation: the effect of PaCO2 on blood flow, oxygen availability, oxygen consumption rate and ERG in monkeys. PMID- 4203071 TI - Proceedings: A comparison of some derivatives of phloretin as prostaglandin antagonists. PMID- 4203072 TI - Proceedings: The effect of increased intraocular pressure on the endothelium of Schlemm's canal. PMID- 4203073 TI - Proceedings: Experimental iris suture in primates. PMID- 4203074 TI - Unequivocal identification of sphingomyelin in the lipids of Tetrahymena pyriformis. PMID- 4203075 TI - Behavioral effects of tularemia and sandfly fever in man. PMID- 4203076 TI - Interaction of lipopolysaccharides with mitochondria. II. Effects of magnesium ions on toxicity of a rough lipopolysaccharide. PMID- 4203077 TI - Immune response of the human respiratory tract. II. Cell-mediated immunity in the lower respiratory tract to tuberculin and mumps and influenza viruses. PMID- 4203078 TI - Immunogenicity of group A and group C meningococcal polysaccharides in human infants. PMID- 4203079 TI - Growth of measles virus in the lymphoid tissues of monkeys. PMID- 4203081 TI - Pancreatic-type tissue in livers of rats fed polychlorinated biphenyls. PMID- 4203080 TI - Inhibition of DNA and protein synthesis in melanocytes by a melanoma extract. PMID- 4203082 TI - Replication of bacteriophage SH-133 in the facultative autotroph Hydrogenomonas facilis. I. Bacteriophage synthesis under heterotrophic, autotrophic, and mixotrophic growth conditions. AB - The ability of bacteriophage SH-133 to replicate in heterotrophically (H-) and autotrophically (A-) grown Hydrogenomonas facilis was examined. Both the synthesis of infectious phage particles and the efficiency of plating (EOP) were reduced by 90% in A-grown cells. Adsorption of phage and lethal effects on H. facilis were identical in both systems. One-step growth experiments showed that cell lysis preceded the appearance of infectious particles in A-grown cells. Burst size studies with mixotrophically grown cells did not indicate the presence of an inhibitor of phage synthesis indigenous to autotrophic metabolism. DNA synthesis was identical in H- and A-grown infected cells; however, protein synthesis was significantly reduced in A-grown infected cells when compared with protein synthesis in H-grown infected cells. The data suggest that the reduction in EOP and phage synthesis in A-grown cells is caused by a defect in viral protein synthesis which results in the limited production of an essential viral protein at the time of cell lysis. PMID- 4203083 TI - Synthesis of the unusual DNA of Bacillus subtilis bacteriophage SP-15. AB - Cultures of Bacillus subtilis infected with phage SP-15 were examined to investigate the metabolic origin of two of the unique components of the phage DNA: the component responsible for the unusually high buoyant density in CsCl and the unusual pyrimidine, 5-(4', 5'-dihydroxypentyl) uracil (DHPU). Newly synthesized pulse-labeled DNA was light in buoyant density and shifted to the high density of mature phage DNA upon further incubation. Parental DNA was converted to a light-density intermediate form prior to replication. When labeled uracil, thymidine, or DHPU were added to infected cells, it was found that only uracil served as the precursor to DHPU and thymine in phage DNA. Analysis of the bases from hydrolyzed DNA of labeled phage or infected cells indicated that the uracil was incorporated into the DNA as such (presumably via deoxyuridine triphosphate) and later converted to DHPU and thymine at the macromolecular level. The sequence of events after phage infection appeared to be: (i) injection of parental DNA; (ii) conversion of parental DNA to a light form; (iii) DNA replication, yielding light DNA containing uracil; (iv) conversion of uracil to DHPU and thymine; and (v) addition of the heavy component. PMID- 4203084 TI - Replication of bacteriophage SH-133 in the facultative autotroph Hydrogenomonas facilis. II. Bacteriophage synthesis and hydrogenase induction under step-up and step-down growth conditions. AB - Autotrophically grown infected cells are able to replicate phage SH-133 after being switched to a heterotrophic environment (step-up growth). The effect of step-down growth on phage replication varies with the choice of organic substrate. Phage replication and the induction of cellular hydrogenase occur under step-down growth from acetate but not peptone broth. The requirement of a continued source of energy for phage replication in either heterotrophically or autotrophically grown cells could be uniquely demonstrated in this phage-host system by the deletion of hydrogen from the growth medium. PMID- 4203085 TI - Viral protein synthesis in bacteriophage phi 29-infected Bacillus subtilis. AB - Twenty-three (14)C-labeled phage phi29-specific proteins in lysates of UV irradiated Bacillus subtilis have been resolved by sodium dodecyl sulfate polyacrylamide gel electrophoresis and identified by autoradiography. Included in this group of proteins are the six major structural proteins of the virion. Analysis of the temporal sequence of viral protein synthesis indicates that three groups of proteins can be identified by time of appearance, beginning at 2 to 4, 4 to 6, or 8 to 10 min after infection, respectively. These proteins account for approximately 90% of the coding capacity of the phi29 genome. PMID- 4203086 TI - Isolation and characterization of a bacteriophage for Thiobacillus novellus. AB - A DNA-containing bacteriophage for Thiobacillus novellus has been isolated from sewage and purified by ammonium sulfate precipitation, differential centrifugation, and cesium chloride equilibrium centrifugation. The buoyant density of this phage in CsCl is 1.51 g/cm(3). Electron microscopy studies have revealed a polyhedral head about 60 nm in diameter and a tail surrounded by a number of fine filaments. It has an adsorption rate constant of 1.1 x 10(-9) ml/min, a latent period of 45 min, and an average burst size of 150. The mole guanine and cytosine content in its DNA has been estimated to be 57 to 58%. Five structural proteins with molecular weights of 62,000, 42,500, 30,500, 17,750, and 13,500 have been detected by polyacrylamide gel electrophoresis techniques. PMID- 4203088 TI - Triiodothyronine. Physiological and clinical significance. PMID- 4203087 TI - Characterization of virus-specific RNAs from subacute sclerosing panencephalitis virus-infected CV-1 cells. AB - CV-1 cells infected with subacute sclerosing panencephalitis (SSPE) virus incorporated uridine-(3)H into at least four virus-specific RNA components in the presence of actinomycin D. The component sedimenting fastest had a sedimentation coefficient of 50s corresponding to a molecular weight of 6 x 10(6). The other three RNA components have sedimentation constants of 35s, 22s, and 18s corresponding to molecular weights of 2.5 x 10(6), 1.0 x 10(6), and 0.75 x 10(6), respectively. The base composition of the 50s RNA is distinct from that of cellular RNA and comparable with base compositions of viral RNAs of other paramyxoviruses. The base composition of the 18s RNA shows approximate complementarity with the 50s RNA. RNA-RNA annealing experiments using unlabeled 50s SSPE RNA with labeled 18s RNA from cells infected with SSPE virus or measles virus show 100% annealing with 18s SSPE RNA but only 60% annealing with 18s measles RNA. These experiments suggest some differences between the 18s RNAs of SSPE virus-infected cells and measles virus-infected cells. PMID- 4203089 TI - Letter: Jet lag ketoacidosis. PMID- 4203090 TI - Intracellular components associated with Chikungunya virus-specific ribonucleic acids in infected BHK21 cells. PMID- 4203091 TI - FP5 factor, an undescribed sex factor of Pseudomonas aeruginosa. PMID- 4203092 TI - Studies on murine leprosy bacillus. VII. Temperature range and temperature optimum for the growth of the supposed murine leprosy bacillus. PMID- 4203093 TI - [Letter: No increase of liver carcinoma following anabolic therapy]. PMID- 4203094 TI - Control of infections from intravenous infusions. PMID- 4203095 TI - [Proceedings: Diaphragmatic hernia from the viewpoint of the internist]. PMID- 4203096 TI - [Distribution of ABO blood groups and Rh factor in patients with pulmonary cancer]. PMID- 4203097 TI - [State of the blood histamine-histaminase system in recipients in transfusions of blood components]. PMID- 4203098 TI - Immunological characterization of anti-haemophilic factor A related antigen in haemophilia A. PMID- 4203099 TI - [The efficacy of laboratory washing machines for cleaning and disinfecting anaesthetic equipment (author's transl)]. PMID- 4203100 TI - Failure to thrive, in Lebanon. II. An investigation of the causes. PMID- 4203101 TI - Determination of glomerular filtration rate in the newborn. Comparison between results obtained by the single injection technique without collection of urine and the standard clearance technique. PMID- 4203102 TI - Diagnostic significance of serum orosomucoid level in bacterial infections during neonatal period. PMID- 4203103 TI - Effect of fasting and of a protein free diet on amino acid ratios in plasma and erythrocytes in rats. PMID- 4203104 TI - Safety aspects on long-term medication. PMID- 4203105 TI - Generalized mucormycosis in the golden-bellied mangabey (Cercocebus galeritus chrysogaster, Lydekker). PMID- 4203106 TI - [Ecological specificity of the Ophryoscolescides ciliate]. PMID- 4203107 TI - [Pseudotuberculosis of a monkey (Cercopithecus cephus, Lin) caused by Yersinia enterocolitica]. PMID- 4203108 TI - Pathological findings on animals in the Royal Zoological Gardens of the Rotterdam Zoo during the years 1963, 1964 and 1965. PMID- 4203109 TI - A method for determination of the synthesis rate of stable and unstable ribonucleic acid in Escherichia coli. PMID- 4203110 TI - Therapeutic implications of copper deficiency in Menkes's steely-hair syndrome. PMID- 4203111 TI - [Nervous system lesions in hemorrhagic fever in monkeys]. PMID- 4203112 TI - [Transmission with the use of DNA of the character of resistance to high boron content of soil in Bacillus megaterium]. PMID- 4203113 TI - [Normal values and distribution of transferrin in adults]. PMID- 4203114 TI - [Blood groups and leprosy in Angola populations]. PMID- 4203115 TI - Kinetics of beta-lactamase inactivation of penicillins. II. Effect of competitive inhibitors. PMID- 4203116 TI - [Experimental studies on Ardisia japonica in the treatment of chronic bronchitis]. PMID- 4203117 TI - [Anthorhododendrin in the treatment of chronic bronchitis: report of 212 cases]. PMID- 4203118 TI - [Etiology of chronic bronchitis]. PMID- 4203119 TI - [Selective coronary arteriography. I. A preliminary report on methods]. PMID- 4203120 TI - [Chronic disseminated intravascular coagulation--report of a successfully treated case of giant hemangioma of the spleen]. PMID- 4203122 TI - [Long-term effects of radiotherapy in 517 cases of cervix carcinoma]. PMID- 4203121 TI - [Interpretations of radiographic signs of cartilaginous lesions]. PMID- 4203123 TI - [Surgical treatment of intrathoracic meningocele--report of a case]. PMID- 4203124 TI - [Notes from a conference on prevention and treatment of pneumonia in children]. PMID- 4203125 TI - [Chronic pulmonary heart disease: acid-base imbalance and changes in electrolytes]. PMID- 4203126 TI - [Ph chromosome]. PMID- 4203127 TI - [Clinicopathological conference no. 10. Irregular fever lasting for 4 months, jaundice, convulsion and hepatosplenomegaly]. PMID- 4203128 TI - Cryoglobulinaemia in tropical splenomegaly syndrome. PMID- 4203129 TI - Determination of IgG antiglobulins in rheumatoid disease using insolubilized human IgG. PMID- 4203130 TI - Carcino embryonic antigens (CEA) and non-specific cross-reacting antigens in feces. PMID- 4203132 TI - Evaluation of plasma thyrotrophin response to thyrotrophin releasing hormone in Graves' disease and in hyperactive thyroid adenoma before and after treatment. PMID- 4203131 TI - Regional hemodynamic effects of dopamine in the unanesthetized primate: failure to alter flow-dependent hepatic drug clearance. PMID- 4203133 TI - [Behavior of plasmatic TSH in pituitary neoplasms after stimulation with thyrotropin releasing hormone (TRH)]. PMID- 4203134 TI - [Feto-maternal conflict in the ABO, Rh and HL-A systems. 3. Incidence of premature labors]. PMID- 4203135 TI - [Intermittent or simplified continuous treatment with basic drugs with restricted use of PAS in newly diagnosed pulmonary tuberculosis. 3. Bacteriological analysis of the study]. PMID- 4203136 TI - Prevention of periodontal disease--a pathologist's view. PMID- 4203137 TI - Effects of intense auditory stimulation: hearing losses and inner ear changes in the squirrel monkey. II. PMID- 4203138 TI - Primate head restrainer using a nonsurgical technique. PMID- 4203139 TI - Production of anti-idiotypic and anti-class specific antibody using micro amounts of myeloma serum. PMID- 4203140 TI - N-alkylnorketobemidones with strong agonist and weak antagonist properties. PMID- 4203142 TI - Synthetic trypanocides. 3. Structure-activity relationships. PMID- 4203141 TI - Thiourea derivatives of 2-aminooxazoles showing antibacterial and antifungal activity. PMID- 4203143 TI - Calcium and phosphorus homeostasis in horses. PMID- 4203144 TI - Effect of carbohydrate load by intravenous infusion in fasted rats on liver glucose-6-phosphate dehydrogenase and malic enzyme. PMID- 4203145 TI - Haematological relationships between New Guinean mothers and their infants. PMID- 4203146 TI - Fatal cerebral oedema with insulitis in diabetic ketoacidosis. PMID- 4203147 TI - [Telemetry-ECG and long term-ECG in the rehabilitative cardiology]. PMID- 4203148 TI - Use of videotape feedback as a psychotherapeutic nursing approach with long-term psychiatric patients: A pilot study. PMID- 4203149 TI - [Development of Isospora bigemina in a tissue culture infected with sporozoites]. PMID- 4203150 TI - Effect of glutaraldehyde fixation on erythrocyte agglutinability. PMID- 4203151 TI - Relation between bacteriocin production and virulence of Streptococcus faecalis var. liquefaciens. PMID- 4203152 TI - Effect of chorionic gonadotropin on corpus luteum of the monkey. PMID- 4203153 TI - The isolation of mutants of Aspergillus flavus and A.parasiticus with altered aflatoxin producing ability. PMID- 4203154 TI - Pathogenic effects of Cladosporium herbarum and Penicillium decumbens. PMID- 4203155 TI - [Scholastic performance of epileptic children in comparision with a control group]. PMID- 4203156 TI - [Family studies on the genetics of focal seizures]. PMID- 4203157 TI - Some aspects of intracellular parasitism. AB - In intracellular parasitism the host cell is a true and hospitable host. The parasite does not have to break in the door. It has subtle ways of inducing the host to open the door and welcome it in. One of the exciting fields in the future of parasitology is to find out what these ways are and why they are sometimes so highly specific that the cell that invites one parasite in will not open the door to another closely related species. Once inside, the parasite not only exploits nutrients already available in the cell, and the cell's energy-yielding system, but it further induces the cell to assist actively in its nutrition. Like a bandit who has cajoled his way in, the parasite now forces his host to prepare a banquet for him. Finally it may destroy its host cell, as in most of the associations I have described herein, or it may stimulate its host cell to abnormal increase in size or to have an altered metabolism with the formation of new products. Or it may even contribute some positive benefit to the host cell or to the multicellular organism of which the cell is a part, so that the two kinds of organisms then live together in a state of mutualism or symbiosis (26). PMID- 4203158 TI - Progress of tuberculous diabetes coming under supervision during the years 1953 65 up to July 1972. PMID- 4203160 TI - The differential tuberculin test in a BCG vaccinated population. PMID- 4203159 TI - Drug resistant pulmonary tuberculosis treated with ethambutol and rifampicin in North East England. PMID- 4203161 TI - Cumulative effects of pulsed exposures of mycobacterium tuberculosis to isoniazid. PMID- 4203162 TI - Co-operative controlled trial of a standard regimen of streptomycin, PAS and isoniazid and three alternative regimens of chemotherapy in Britain. A report from the British Medical Research Council. PMID- 4203163 TI - Bladder toxicity due to cyclophosphamide. Experimental induction and treatment. PMID- 4203164 TI - Rapid development of carcinoma in diverticulum of the bladder. A pitfall in conservative management. PMID- 4203165 TI - A possible D(CW) (e) gene complex of the Rh system. PMID- 4203166 TI - Blood group O(H)-like activity in extracts from some invertebrates. A study with catfish and eel sera and three anti-H lectins. PMID- 4203167 TI - Small scale preparation and clinical use of factor IX-prothrombin complex. PMID- 4203168 TI - Automated screening test for high titre tetanus antibody in donor plasma. PMID- 4203169 TI - The role of rheumatoid factor and related human antiglobulins in the radioimmunoassay (Ausria system) for the detection of hepatitis B antigen. PMID- 4203170 TI - [Preparation of diabetics for oral surgery]. PMID- 4203171 TI - [Quantitative immunoglobulin determinations in hepatobiliary diseases. Discriminant analytical study]. PMID- 4203172 TI - [Parenteral feeding]. PMID- 4203173 TI - Free zone electrophoresis of amniotic fluid in normal pregnancies and in pregnancies complicated by haemolytic disease. PMID- 4203174 TI - Studies on reovirus-antigens. I. Preparation of reovirus-specific immune serum in the rabbit by means of active immunization through the scarified skin. PMID- 4203175 TI - Studies on reovirus-antigens. II. Segregation of reovirus-antigens by chromatography on ecteola-cellulose and by centrifugation in a sucrose density gradient. PMID- 4203176 TI - Kinetics of the attachment of radioisotope-labelled adenovirus hemagglutinins to red blood cells and their detachment by antibody and by nonlabelled hemagglutinins of homologous and heterologous types. PMID- 4203177 TI - Effect of water on the bacterial flora of swimmers' ears. PMID- 4203179 TI - Infantile sexuality in monkeys. PMID- 4203178 TI - Trigeminal-facial nerve communications. Their function in facial muscle innervation and reinnervation. PMID- 4203180 TI - Equations of substrate-limited growth: the case for blackman kinetics. PMID- 4203181 TI - Detection of myeloma cells in the urine sediment. PMID- 4203182 TI - Polychlorinated biphenyls in the seastar Acanthaster planci. PMID- 4203183 TI - Demonstration of 2-oxoglutarate: glyoxylate carboligase activity in Tetrahymena pyriformis. PMID- 4203184 TI - Inhibition of ribonuclease activity by bentonite. PMID- 4203185 TI - [Tympanoplasty type 3--a cavum major technic]. PMID- 4203186 TI - [Tympanoplasty]. PMID- 4203187 TI - [Treatment of sudden deafness with Radix Puerariae (with analysis of therapeutic results in 294 cases)]. PMID- 4203188 TI - [Neck dissection for malignant oral and maxillofacial tumors: clinicopathological analysis of 419 cases]. PMID- 4203189 TI - [Evaluation of temporomandibular arthrography in temporomandibular joint dysfunction; analysis of 67 cases]. PMID- 4203190 TI - [Classification and diagnosis of dysfunction of the temporomandibular joint]. PMID- 4203191 TI - [Bone grafting in temporomandibular ankylosis: a preliminary report]. PMID- 4203192 TI - [Combined Chinese and Western therapy in nephrotic syndrome]. PMID- 4203193 TI - [Acupuncture sensation and the electromyogram of the needle point in patients with nervous system diseases]. PMID- 4203194 TI - [Intrachondral microcirculation and cartilage growth (embryonic cartilage and bone development)]. PMID- 4203195 TI - [Antibacterial activity of Senecio scandens and its clinical efficacy]. PMID- 4203197 TI - [Clinicopathological conference. Case 7 and 8,--acute macroscopic hematuria, with blood clot]. PMID- 4203196 TI - [Antibacterial therapy in pyelonephritis]. PMID- 4203198 TI - Prefrontal lobe functions and the neocortical commissures in monkeys. PMID- 4203199 TI - Mesencephalic control of lateral geniculate nucleus in primates. I. Electrophysiology. PMID- 4203200 TI - Mesencephalic control of lateral geniculate nucleus in primates. II. Effective loci. PMID- 4203201 TI - Mesencephalic control of lateral geniculate nucleus in primates. 3. Modifications with state of alertness. PMID- 4203202 TI - A controlled trial of ambulant out-patient treatment and in-patient rest in bed in the management of tuberculosis of the spine in young Korean patients on standard chemotherapy a study in Masan, Korea. First report of the Medical Research Council Working Party on Tuberculosis of the Spine. PMID- 4203203 TI - Anterior fusion of the spine for infective lesions in adults. PMID- 4203204 TI - Non-flagellate Pseudomonas aeruginosa in pathological material. AB - Three isolates of non-flagellate Pseudomonas aeruginosa obtained from pathological material of human cases are described. Two were found in urinary tract infections and the third in a respiratory infection. They were shown by typing methods to be distinct strains. PMID- 4203205 TI - An automated method for the microbiological assay of serum pyridoxal. AB - A fully automated method for the measurement of serum pyridoxal has been developed. Acid phosphatase was used for dephosphorylation and precipitation of the serum proteins was not required. A chloramphenicol-resistant strain of L. casei was used as the test organism and this removed the need for sterilization. The method gives highly reproducible results, and is suitable for population and institutional studies. PMID- 4203206 TI - Influence of temperature on Drosophila alcohol dehydrogenase polymorphism. PMID- 4203207 TI - Inactivation of endotoxin by serum: a phylogenetic study. PMID- 4203208 TI - Notes. Studies of amniotic fluid in women infected with rubella. PMID- 4203209 TI - Neuronal alterations in developing cortical infarction. An experimental study in monkeys. PMID- 4203210 TI - Cerebral radiation necrosis simulating a brain tumor. Case report. PMID- 4203211 TI - Adrenergic mechanism in Tetrahymena. II. Effect of adrenaline on cell proliferation. PMID- 4203212 TI - Vasodilating effect of crude platycodin in anesthetized dogs. PMID- 4203214 TI - Change in catecholamine content of Tetrahymena pyriformis W during growth. PMID- 4203213 TI - Comparative studies of hepatic nicotine metabolizing enzyme activities in monkeys and dogs. PMID- 4203215 TI - Comparison of two test kit methods for detection of occult blood in animal faeces. PMID- 4203216 TI - [Amino acid composition of blood plasma and urine in patients with postoperative stomach disorder during parenteral nutrition weith protein hydrolysates of various composition]. PMID- 4203217 TI - ["Sorbit for injections" as an energy source for parenteral nutrition of patients]. PMID- 4203218 TI - [Biological value of preparations for parenteral nutrition made of different raw materials and some ways of their improvement]. PMID- 4203219 TI - [Parenteral nutrition in the treatment of patients with surgical pathology of the abdominal organs]. PMID- 4203220 TI - [Parenteral nutrition before and after the gastrointestinal surgery]. PMID- 4203221 TI - [Parenteral nutrition in the complex treatment of diffuse peritonitis]. PMID- 4203222 TI - [Use of protein hydrolysates together with other preparations for the stimulation and increase of the body reactivity in surgical patients]. PMID- 4203223 TI - [Current problems of the parenteral protein nutrition]. PMID- 4203224 TI - [Effectiveness of protein hydrolysate, casein, in the treatment of chronic enterocolitis]. PMID- 4203225 TI - [Parenteral protein nutrition in deep burns]. PMID- 4203226 TI - [Parenteral nutrition with protein hydrolysates as a method of correction of protein metabolism disturbances in burns]. PMID- 4203227 TI - [Correction of protein deficiency in children in the early postoperative period]. PMID- 4203228 TI - [Parenteral nutrition of patients with cancer of the stomach and esophagus in the postoperative period]. PMID- 4203229 TI - [Prevention of reactions in the transfusions of protein hydrolysates on account of the increase in their assimilation]. PMID- 4203230 TI - [Pathophysiological basis of the methods used to enchance the effect of parenteral nutrition]. PMID- 4203231 TI - [Significance of the use of protein hydrolysates in clinical practice]. PMID- 4203232 TI - [Comparison of methods of detecting staphylococcal enterotoxin in food]. PMID- 4203234 TI - [Vitamin B6--pyridoxine. Old and new information of biochemical and clinical interest]. PMID- 4203233 TI - [Treatment of acute bronchopulmonary diseases. Double-blind study of a trimethoprim-sulfamethoxazole combination as compared with demthylchlortetracycline]. PMID- 4203236 TI - [Morphological changes in the cartilage of the pinna in adult rabbits after cryosurgery using different temperatures and exposure times (author's transl)]. PMID- 4203235 TI - [Proceedings: Results of a controlled trial of intermittent ambulatory therapy of infectious pulmonary tuberculosis with comparison of various maintenance regimens]. PMID- 4203237 TI - [General characteristics of impulse sequences in bioacoustic signals]. PMID- 4203238 TI - Homologous interference of lymphocytic choriomeningitis virus. PMID- 4203239 TI - Comparative analysis of interlaboratory variation in drug sensitivity test for Mycobacterium tuberculosis. PMID- 4203240 TI - Bacteriophage typing of Mycobacterium ranae (Fortuitum). The correlation of lysis by mycobacteriophage BK4 and inositol utilisation. PMID- 4203242 TI - Production of cold agglutinins in rabbits induced by Mycoplasma pneumoniae, Listeria monocytogenes or Streptococcus MG. PMID- 4203243 TI - Placental function and oxygenation in the fetus. PMID- 4203241 TI - Haemolytic activity of various strains of Acinetobacter. PMID- 4203244 TI - Morphological determinants in O2-transfer across the human and Rhesus hemochorial placenta. PMID- 4203245 TI - Threshold values of oxygen deficiency leading to cardiovascular and brain pathological changes in term monkey fetuses. PMID- 4203246 TI - Experimental models for in vivo and in vitro investigations on placental hemodynamics and oxygen supply to the fetus. PMID- 4203247 TI - Existing anatomical parameters and the need for further determinations for various tissue structures. PMID- 4203248 TI - Effect of carbonic anhydrase on the facilitated diffusion of CO2 through bicarbonate solutions. PMID- 4203249 TI - Serial passage of 3 strains of avian infectious bronchitis virus in African green monkey kidney cells (VERO). PMID- 4203250 TI - Effect of virus pathogenicity on antibody production in Marek's disease. PMID- 4203251 TI - Isolation of type-A influenza viruses from imported exotic birds. PMID- 4203253 TI - An easy method for making cutters to use in the agar-gel diffusion technique. PMID- 4203252 TI - Role of desquamated epithelial cells in transmission of Marek's disease. PMID- 4203254 TI - [Evaluation of the City of Aachen serologic expert opinions with reference to characteristics leading to the exclusion of paternity]. PMID- 4203255 TI - [Anomalies of the complement system in human nephropathies]. PMID- 4203256 TI - [Functional examination of lungs during "intal" therapy in children and adolescents with bronchial asthma]. PMID- 4203258 TI - Time course of weight increase of anterior pituitary and thyroxine binding to adenopituitary proteins after a single administration of estrogen. PMID- 4203257 TI - [Red blood cell levels of acetylcholinesterase in newborn infants with hyperbilirubinemia and asphyxia]. PMID- 4203259 TI - The detection of LH activity in sheep urine by radioimmunoassay. PMID- 4203260 TI - [Observations on the delivery behaviour in the common Marmoset (Callithrix jacchus Erxleben, 1777) (author's transl)]. PMID- 4203261 TI - Notes on reproduction in captive squirrel monkeys (Saimiri sciureus). PMID- 4203262 TI - Evaluation of the water incentive method of social dominance measurement in primates. PMID- 4203263 TI - Blood groups, red cell enzymes and serum proteins of baboons and vervets. PMID- 4203264 TI - Applicability of heat-stable deoxyribonuclease assay for assessment of staphylococcal growth and the likely presence of enterotoxin in cheese. PMID- 4203265 TI - Effect of pesticides on the methylene blue reduction test in milk. PMID- 4203266 TI - [Familial cases of Hunter's syndrome]. PMID- 4203268 TI - [Use of a vinyl chloride tube as a connector in tube feeding]. PMID- 4203267 TI - [Case of Pseudomonas aeruginosa meningitis with the syndrome of inappropriate secretion of ADH]. PMID- 4203269 TI - Are all those lab tests really worth it? PMID- 4203270 TI - [Type 3 mucolipidosis. 2 cases in siblings. Clinical and ultrastructural study]. PMID- 4203271 TI - [Some results in the examination of the biological effect of snythetic thyrotropin-releasing factor]. PMID- 4203273 TI - Summary of recent studies in Japan on methyl mercury poisoning. PMID- 4203272 TI - [Radioimmune method for determination of thyrotropic hormone in rat's blood plasma]. PMID- 4203274 TI - [Secretion of insulin under the influence of sulfonylurea derivates (SH)]. PMID- 4203275 TI - Studies on the mechanism of learning. II. On the ionic nature of the dendritic action potentials and mescaline spikes. PMID- 4203276 TI - [Double-blind test in comparison of a chemotherapeutic and antibiotic treatment of current infectious stomatological pathology]. PMID- 4203278 TI - Local oxygen tension and blood flow in the normal and chronic ischemic myocardium in the anesthetized dog. PMID- 4203277 TI - Observations on the effect of changes in arterial oxygenation on adenosine induced coronary vasodilation. PMID- 4203279 TI - The effect of glyceryl trinitate on coronary collateral flow--a preliminary report. PMID- 4203280 TI - Coronary artery reperfusion: early effects on coronary hemodynamics. PMID- 4203281 TI - [Long-term studies on the trabecular meshwork of cynomolgus monkeys after trabeculectomy (author's transl)]. PMID- 4203282 TI - [Combination of disk-electrophoresis and immunodiffusion for protein analysis of aqueous humor (author's transl)]. PMID- 4203283 TI - Effect of incubation time on folate values. PMID- 4203285 TI - Clarification of sonic lysates of Mycobacterium tuberculosis. PMID- 4203284 TI - Simple pyrazinamidase and urease tests for routine identification of mycobacteria. PMID- 4203287 TI - Modern concepts in the management of surgical diabetic patients. PMID- 4203286 TI - Isolation of tuberculin skin test reactive proteins from heated culture filtrate of Mycobacterium tuberculosis H37Rv. PMID- 4203288 TI - Polycystic jaws in patients with cleft lip and palate. PMID- 4203289 TI - Comparative observations on intertubular lymphatics and the organization of the interstitial tissue of the mammalian testis. PMID- 4203290 TI - Periodic thermal stress: optimal spacing predicted by a simple set-back model of cell division synchronization. PMID- 4203291 TI - Failure of TSH radioimmunoassay to consistently detect mild TSH mediated thyroid stimulation. PMID- 4203293 TI - Serum TSH responses to intravenously and orally administered TRH in man after thyroidectomy for carcinoma of the thyroid. PMID- 4203292 TI - Serum triiodothyronine in health and disease. PMID- 4203294 TI - Mesenteric lymph as a major source of serum IgA in guinea pigs and rats. PMID- 4203295 TI - Bursal and postbursal stem cells in chicken. Functional characteristics. PMID- 4203296 TI - Mendelian segregation of a mouse antibody idiotype. PMID- 4203297 TI - [Hypersecretory states of the pancreas: implications in the physiopathology of pancreatic inflammation]. PMID- 4203298 TI - [Selective abdominal arteriography for the diagnosis of primary and metastatic tumors of the liver and pancreas]. PMID- 4203299 TI - [On the results of 500 examinations made with the Lo Presti esophago gastroscope]. PMID- 4203300 TI - [Small supporting mask to hold esophagogastric compression tubes]. PMID- 4203301 TI - [Transparietohepatic cholangiography]. PMID- 4203302 TI - [Esophagogastric endoscopy in some systemic diseases. Preliminary report]. PMID- 4203304 TI - Growth hormone levels in vitamin B6-deficient rats. PMID- 4203303 TI - [Corrosive injuries of the oesophagus and their treatment (author's transl)]. PMID- 4203305 TI - Plasma disappearance of radioiodinated dog growth hormone in the dog. PMID- 4203306 TI - Importance of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosis. PMID- 4203307 TI - Studies on the conjugation of horseradish peroxidase to Fab fragments. PMID- 4203308 TI - Micro-hemagglutination tests for detection of native and single-strand DNA antibodies and circulating DNA antigen. PMID- 4203310 TI - Proceedings: The mechanism of action of prostaglandin F2a on cerebral flow in the baboon. PMID- 4203309 TI - Differential effects of glycerol treatment on membrane capacity and excitation contraction coupling in toad sartorius fibres. AB - Changes in membrane capacity and excitation-contraction coupling caused by glycerol movements have been investigated in toad sartorius fibres using a standard glycerol-Ringer solution containing 400 mM glycerol.1. The rates of glycerol movement, in and out of fibres, were determined by measuring diameter changes in single fibres. Glycerol equilibrated across the surface membrane within 20-25 min after changes in extracellular glycerol concentration.2. The reduction in membrane capacity, which occurs when glycerol-loaded fibres are returned to Ringer solution, was slower than, and not dependent on, changes in fibre volume.3. To obtain the maximum reduction in membrane capacity, it was necessary to expose fibres to glycerol-Ringer for 50-60 min and then to return them to Ringer for at least 60 min. If preparations were not kept in Ringer for the full 50-60 min, the reduction in membrane capacity could be partially or completely reversed by returning the fibres to glycerol-Ringer.4. When fibres were exposed to glycerol-Ringer there was an initial transient contracture: twitches and K contractures were rapidly inhibited, and then slowly recovered over the next 40-50 min. In some preparations, eventual potentiation of twitches was seen.5. When returned to Ringer solution after 60 min in glycerol-Ringer, preparations lost twitches and K contractures within 5-10 min. The time course of this effect was very similar to the time course of the recovery of the normal volume after the initial swelling.6. The briefer the exposure to the glycerol Ringer, the slower the loss of twitches and K contractures on return to Ringer. In contrast to the loss of membrane capacity, the lesion of excitation contraction coupling was essentially irreversible. Exposure times as brief as 5 min were eventually effective in producing paralysed fibres which, however, still responded to caffeine.7. The differences in the glycerol load-times required to produce decoupling of excitation and contraction, and disconnexion of the transverse tubules, show that the two effects are separable and that the first does not depend on the second.8. It is proposed that the two lesions obtained in glycerol-treated fibres may be related to distension of the transverse tubular system. It is shown in an Appendix that the outward movement of glycerol from sarcoplasm to transverse tubules would be expected to produce some early swelling of the tubules and this is related to the loss of contraction. Furthermore, much greater swelling would occur if a slow-loading compartment (presumed to be the sarcoplasmic reticulum) dumped glycerol into the transverse tubules: it is thought that this is related to the disconnexion of the transverse tubules. PMID- 4203311 TI - Proceedings: Reactive hyperaemia in the dog heart: assessment of post-hyperaemic coronary vascular reactivity and of the effects of temporarily restricting arterial inflow. PMID- 4203312 TI - Proceedings: Extrinsic and intrinsic hysteresis of intrapulmonary bronchi in situ. PMID- 4203313 TI - Dexamethasone in the management of kerosene pneumonia. PMID- 4203314 TI - [Diagnostic and therapeutic aspects of Wilson's disease in the preclinical stage]. PMID- 4203315 TI - Growing and embedding fern gametophytes for autoradiographic studies. PMID- 4203316 TI - A method of fixing rat testis for light and electron microscopy. PMID- 4203317 TI - [Megavolt therapy of bladder tumors]. PMID- 4203319 TI - [Dosimetry device for medically used particle accelerators]. PMID- 4203318 TI - [Kinetoradiotherapy of parametria and of the pelvic lymphatic drainage area using ultra-hard roentgen rays]. PMID- 4203320 TI - Regulation of transport systems: a means of controlling metabolic rates. PMID- 4203321 TI - Control of photosynthetic carbon metabolism. PMID- 4203322 TI - Bladder neck obstruction in young male patients. PMID- 4203323 TI - Cecovesicovaginal fistula. PMID- 4203324 TI - [ST-T segment changes in the ECG in factitial thyrotoxicosis]. PMID- 4203325 TI - [The appearance of pregnancy typical proteins during the use of hormonal contraceptives]. PMID- 4203326 TI - [Vascular manifestations of Recklinghausen's disease. Apropos of a case]. PMID- 4203327 TI - [Value of human gamma spectrometry in the determination of total potassium changes in cardiac patients. 1st results concerning 200 subjects]. PMID- 4203328 TI - [Production of levorin in mixed cultures with different microorganisms]. PMID- 4203329 TI - [Study of equilibrium in the system butylacetate-penicillin-aqueous medium]. PMID- 4203330 TI - [Sensitivity of gonococci to ampicillin, oxacillin and benzylpenicillin]. PMID- 4203332 TI - Field evaluation of the gel diffusion test for the diagnosis of ram epididymitis caused by Brucella ovis. AB - A comparison was made with the microslide gel diffusion technique, the complement fixation test, cultural isolation, and clinical examination in detecting ram epididymitis caused by Brucella ovis. The results of the gel diffusion method are shown to be similar to those obtained by the complement fixation test and isolation of B. ovis from cultures of semen. The technique offers a reliable diagnostic method adaptable to field use in controlling ovine brucellosis and is more practical. PMID- 4203331 TI - Effect of pH, sodium chloride, and sodium nitrite on enterotoxin A production. AB - The combined effects of pH, sodium chloride, and sodium nitrite were studied by using a dialysis sac technique in brain heart infusion broth. Growth and enterotoxin A production by Staphylococcus aureus strain 100 were found to decrease with the addition of sodium nitrite, with a decrease in pH from 7.0, and with an increase in sodium chloride concentration. The significance of these results is discussed in relation to cured meats. PMID- 4203333 TI - Multiplication of nosocomial pathogens in intravenous feeding solutions. AB - A major problem in total parenteral nutrition is sepsis, particularly that caused by Candida. Studies of four solutions, a casein hydrolysate, a fibrin hydrolysate, and two crystalline amino acid solutions, show that the protein hydrolysate solutions appear to be highly selective for Candida over bacteria, whereas the crystalline amino acid solutions are not. These findings suggest that the crystalline amino acid preparations may offer a partial solution to the infection problem by minimizing the contribution of the solution as a reservoir for organism multiplication, because they retard the growth of both bacteria and Candida. PMID- 4203334 TI - Comparison of three culture media for isolation of Mycobacterium tuberculosis: a 6-year study. AB - Among 2,648 specimens positive on culture for Mycobacterium tuberculosis over a 6 year period, 82% grew on Lowenstein-Jensen medium (LJ), 79% on American Trudeau Society (ATS), and 56% on Middlebrook 7H10 (7H10). When these commercial culture media were compared in regard to the number of acid-fast bacilli seen on the original smears, LJ cultures were found to have the highest isolation rates for each smear category, and 7H10 had the lowest rates. Comparing the media from the aspect of number of mycobacterial colonies produced, LJ and ATS had the highest average colony counts, followed by 7H10. These findings were relatively constant over the 6-year period. One possible reason for the low positive rate of 7H10 was the lack of CO(2) enrichment. PMID- 4203335 TI - Assimilation of hydrocarbons by Pseudomonas strains isolated from human clinical specimens. AB - Twenty strains of Pseudomonas isolated from human clinical specimens on routine laboratory media, without hydrocarbon enrichment and unselected for their growth on hydrocarbons, were tested for their ability to utilize a series of eight n alkanes and two 1-alkenes as a sole carbon and energy source for growth. Hydrocarbon assimilation does occur with such isolates relative to the chain length and the degree of saturation of the hydrocarbon. The data presented show that all 16 stains of Pseudomonas aeruginosa studied grew readily on dodecane through hexadecane and on 1-hexadecene. In addition, most strains of this species grew on undecane and 1-dodecene after prolonged incubation. There was a long lag period, usually a minimum of 4 days, before onset of growth on any hydrocarbon. In no case did hexane or decane support growth. Two strains each of P. maltophilia and P. stutzeri were unable to grow on any of the hydrocarbons tested. Hexane in concentrations above 1% (vol/vol) is bactericidal toward the Pseudomonas inoculum. It is toxic even to cells utilizing different hydrocarbon for growth. The addition of 1% hexane to 1% (vol/vol) hexadecane markedly prolonged the lag phase of P. aeruginosa utilizing the hexadecane for growth. PMID- 4203336 TI - Scanning electron microscopy of bacterial colonies. AB - A technique is described for observing bacterial colony growth. Bacillus cereus, B. subtilis, and B. cereus var. mycoides were grown on strips of dialysis membrane layered on nutrient agar. Microcolonies of the organisms on strips were fixed in Formalin vapor in situ; the strips then were removed from the agar and secured to scanning microscope specimen stubs without markedly disturbing the cellular arrangement. Scanning electron micrographs clearly depict morphology of individual cells, as well as the spatial orientation of cells within the colony. This technique is reproducible, adaptable, and simple. PMID- 4203338 TI - Population changes in enteric bacteria and other microorganisms during aerobic thermophilic windrow composting. AB - Composting of wastes from swine feeding operations was studied. The effects of the frequency of turning the wastes and addition of straw to improve the physical structure were studied to determine the most effective technique to rapidly increase the temperature and, consequently, destroy coliforms and Salmonella. Four different treatments were studied; the results showed that, with addition of 5% (wt/wt) straw and mechanical turning of the compost 20 times per week, the temperature reached 60 C within 3 days and enteric bacteria were destroyed within 14 days. PMID- 4203339 TI - Localized epidermolysis bullosa. Report of two cases and evaluation of therapy with glutaraldehyde. PMID- 4203337 TI - Carbohydrate metabolism in lactic streptococci: fate of galactose supplied in free or disaccharide form. AB - Phosphorylation of free galactose by lactic streptococci was mediated by an adenosine triphosphate (ATP)-dependent kinase. The phosphoenolpyruvate (PEP) phosphotransferase system (PTS) was involved to a limited extent in transport of the sugar. The conversion of free galactose to glucose also was demonstrated, and uridine diphosphogalactose-4-epimerase was demonstrated to account for this change. Galactose, supplied as lactose, was phosphorylated during transport by means of the PTS with PEP as the phosphate donor. Data also indicated that galactose derived from lactose was catabolized by the glycolytic pathway. Results showed the participation of ATP or PEP, or both, in the phosphorylation of five growth sugars for lactic streptococci, namely, galactose, glucose, lactose, maltose, and mannose. Free galactose was phosphorylated exclusively by ATP except when cells were grown on galactose; in this case, slight involvement of PEP in phosphorylation also was noted. Lactose phosphorylation was much more effective with PEP except when cells were grown on lactose, in which case ATP was equally effective. Glucose was phosphorylated to about the same degree by either ATP or PEP. PMID- 4203340 TI - Letter: Photosensitive lichenoid eruption associated with demeclocycline. PMID- 4203341 TI - Azotobacter vineland II RNA polymerase. XI. Effect of transcription on rifampicin binding. PMID- 4203342 TI - Isolation of a replication-complex from eukaryotes. PMID- 4203343 TI - Antigenic homology of eukaryotic RNA polymerases. PMID- 4203344 TI - A new polypeptide associated with RNA polymerase from Bacillus subtilis during late stages of vegetative growth. PMID- 4203345 TI - Effect of age of the rat on induction of acetylcholinesterase of the brain by 17 beta-estradiol. PMID- 4203347 TI - Proceedings: Effect of oxypertine on anxiety-induced behaviour in baboons. PMID- 4203346 TI - Proceedings: Prostaglandin generation maintains the smooth muscle tone of the rabbit isolated jejunum. PMID- 4203348 TI - A comparative study of the accessory ganglia of Axenfeld. PMID- 4203350 TI - [Correlation between severity of haemolytic disease of the newborn and impairment of placental maturation (author's transl)]. PMID- 4203349 TI - Effects of feeding and fasting on the insulin secretory response to glucose and sulfonylureas in intact rats and isolated perfused rat pancreas. PMID- 4203351 TI - [The causes of failures in post partum Anti-D-prophylaxis. 1. Technical errors and feto-maternal transfusions (author's transl)]. PMID- 4203352 TI - [The causes of failures in post partum Anti-D-prophylaxis. 2. Sensitizations prior to the administration of Anti-D-immunoglobulin (author's transl)]. PMID- 4203353 TI - [Maternal-fetal conflict in the ABO, Rh and HL-A systems. II. Appearance of anti HL-A, anti-A, Anti-B and anti-Rh antibodies in pregnancies following unfavorable obstetrical history]. PMID- 4203355 TI - Immunoglobulin classes in mammalian species identifed by cross-reactivity with antisera to human immunoglobulin. PMID- 4203354 TI - Sex-linked blood-glucose pattern in rats under varying test conditions. PMID- 4203356 TI - Characterisation of an allergen extracted from Ascaris suum. Determination of the molecular weight, isoelectric point, amino acid and carbohydrate content of the native allergen. PMID- 4203357 TI - Experience with Bjork-Shiley valvular replacement. A preliminary report. PMID- 4203358 TI - The structure of the zonula occludens. A single fibril model based on freeze fracture. AB - Replicas of freeze-fractured toad urinary bladder and gallbladder were analysed in an attempt to determine the fracturing properties and structure of the zonula occludens (tight junction). Chalcroft and Bullivant have proposed that the junction has a double set of fibrils with one set associated with each of the adjacent cell membranes. However, the fracturing pattern that is observed might also result from only a single set of fibrils which is shared by the adjacent membranes if fracturing occurred around either side of the fibrils. These two models predict quite different structures at regions of the junction where tranl sitions are made between face A and face B. The relative heights of face A and face B and the shape of the transition from face A to face B do not agree with that expected according to the two fibril model but agree exactly with that expected if only a single set of fibrils existed. Further evidence for the single fibril model is derived from fractures of the mucosa membrane which cross the junction to the membrane of the adjacent cell without deflection. Such fractures reveal a single ridge which appears to be identical to the juxtaluminal fibril of the junction. In addition, small ridges are occasionally found in place of the grooves on face B which, although not consistent with the double fibril model, is expected if the single fibril model were correct. Although alternative explanations might account for these observations, we believe that the simplest and most consistent explanation is that the zonula occludens fractures as would be expected of a single set of fibrils shared by adjacent cells. PMID- 4203359 TI - Cryoprotectant-induced redistribution of intramembranous particles in mouse lymphocytes. AB - This study demonstrates, by freeze fracture, clustering of intramembranous particles caused by cryoprotectant treatment of intact unfixed mouse lymphoid cells. Both T and B cells react in a similar fashion, while similar clustering of particles is not observed in some other cell types. The intramembranous particles can be aggregated by incubating unfixed cells in glycerol or dimethylsulfoxide (DMSO) before freezing. The aggregation phenomenon is dependent on the length of time of exposure and the concentration of the cryoprotectants. Further, the cells remain viable and the cryoprotectant-induced clustering is completely reversible. Prefixation of glycerol-treated cells with glutaraldehyde prevents the formation of these particle clusters, and unfixed nonglycerinated cells show no clusters. Thin sections of cells exposed to glycerol or DMSO without previous fixation exhibit bizarre membrane alterations and numerous other degenerative changes. These observations stress the importance of prefixation of lymphoid cells before exposure to glycerol or DMSO, as well as indicate that the membrane characteristics of certain cell types may be probed by glycerol treatment of unfixed cells. PMID- 4203360 TI - The effect of glutaraldehyde on catalase. Biochemical and cytochemical studies with beef liver catalase and rat liver peroxisomes. PMID- 4203362 TI - Studies on the virulence of Neisseria gonorrhoeae. II. Relation of susceptibility to antibiotics and resistance to phagocytosis by polymorphonuclear leukocytes. PMID- 4203361 TI - Nucleolar and perichromosomal RNA synthesis during meiotic prophase in the mouse testis. AB - The transcriptional activity during meiotic prophase in the mouse testis is studied with light microscopy and high-resolution autoradiographic techniques using [(3)H]uridine as a labeled precursor. In the present study, two types of RNA synthesis are detected during meiotic prophase: an extranucleolar RNA synthesis of perichromosomal localization and a nucleolar RNA synthetic activity. In some of the autosomes and close to the basal knobs, the activity of the nucleolar organizers is evidenced by the incorporation of [(3)H]uridine into nucleolar masses from zygotene on and at earlier labeling times. The evolution of nucleoli and the formation of a nucleolus attached to the sex pair are described during the different meiotic stages. Perichromosomal labeling, from leptotene on, reaches a maximum during middle pachytene and falls progressively to a low level at longer incorporation times. Sertoli's cell, the most active RNA synthetic cell in the seminiferous epithelium, rises to a maximum of labeling and drops at earlier times compared with the meiotic prophase cells. The condensed sex chromosomes show some scattered silver grains especially at middle pachytene. The axial chromosome cores and synaptonemal complexes are devoid of silver grains during the meiotic prophase. The observations suggest that a control mechanism operates during meiotic prophase to regulate transcriptional activity in the sex chromosomes and to provide differential RNA synthesis in autosomal bivalents at various stages of prophase and within certain segments of the chromosomes. PMID- 4203363 TI - Current techniques in assessment of protein nutritional status in the community. PMID- 4203364 TI - Synthesis and biological activities of substituted glycyrrhetic acids. PMID- 4203365 TI - Synthesis of 2-oxygenated glycyrrhetic acid derivatives. PMID- 4203366 TI - Antiparasitic 5-nitrothiazoles and 5-nitro-4-thiazolines. 4. PMID- 4203367 TI - Folic acid analogs. Modifications in the benzene-ring region. 4. 3'-Ethyl- and 3' isopropylfolic acids. PMID- 4203368 TI - Synthesis and biological evaluation of isofolic acid. PMID- 4203369 TI - Syntheses and biological activities of 7-ethyl-8-bromo-10-(1'-D ribityl)isoalloxazine and 7-bromo-8-ethyl-10-(1'-D-ribityl)isoalloxazine, analogs of riboflavin. PMID- 4203370 TI - Ribosomal RNA cistrons in Euglena gracilis. PMID- 4203371 TI - Prostaglandin inhibition of metabolically induced coronary vasodilation. PMID- 4203372 TI - Inotropic stimuli and systolic transmembrane calcium flow in depolarized guinea pig atria. PMID- 4203373 TI - Metabolism of diazoxide in man and experimental animals. PMID- 4203374 TI - Pharmacodynamic interactions among gluco-, mineralo- and glucomineralocorticoids, pregnenolone-16alpha-carbonitrile and various drugs. PMID- 4203375 TI - [Renal toxicity of antibiotics (author's transl)]. PMID- 4203376 TI - Plasma and erythrocyte zinc levels in protein-calorie malnutrition. PMID- 4203377 TI - Endotoxemia in the Rhesus monkey: alterations in host lipid and carbohydrate metabolism. PMID- 4203378 TI - [Infection rate among children and adolescents from families including patients with different forms of pulmonary tuberculosis]. PMID- 4203379 TI - [Chronic destructive forms of pulmonary tuberculosis in young persons]. PMID- 4203380 TI - [Methods of isolation of mycobacteriophages]. PMID- 4203381 TI - The absorption, metabolism and excretion of disodium cromoglycate in nine animal species. PMID- 4203382 TI - The relationship between inhibition of delta-aminolevulinic acid dehydratase by lead and lead mobilization by ethylenediamine tetraacetate (EDTA). PMID- 4203383 TI - [Alterations of the autonomic nervous system of parotid gland after administration of antihypertensiva (guanacline). Ultrastructural and fluorescence cytochemical findings on the parotid gland of the rat (author's transl)]. PMID- 4203384 TI - Intraepithelial parasitism as an infection mechanism in human paracoccidioidomycosis (South American blastomycosis). PMID- 4203386 TI - [Clear-cell adenoma of the thyroid gland (author's transl)]. PMID- 4203385 TI - [The effect of long-term cigarette smoke exposure on the cardiovascular system of Syrian golden hamsters (author's transl)]. PMID- 4203387 TI - Human intracranial atherosclerosis. An ultrastructural study of atheromatous plaques. PMID- 4203388 TI - [The significance of agglutinating anti-Rh antibodies in the incidence of hemolytic disease of the newborn (report of a case)]. PMID- 4203390 TI - Observations on asymptomatic infections with Neisseria meningitidis. PMID- 4203391 TI - [Urinary estriol in Rh isoimmunization]. PMID- 4203389 TI - Serum immunoglobulin levels in atomic bomb survivors in Hiroshima, Japan. PMID- 4203392 TI - [On the determination of the germicidal action of surface disinfectants]. PMID- 4203394 TI - Aldolase of lactic acid bacteria: a case history in the use of an enzyme as an evolutionary marker. PMID- 4203393 TI - Reduction of nitrogenous oxides by microorganisms. PMID- 4203397 TI - [Experimental cystitis, a modell of chronic bacteriuria in rats (author's transl)]. PMID- 4203398 TI - Computer morphometrics in craniofacial biology. PMID- 4203400 TI - Increase in the longevity of adult Drosophila melanogaster kept in permanent darkness. PMID- 4203399 TI - [Serum immunglobulin levels in the aged]. PMID- 4203401 TI - The thyroid and age. PMID- 4203402 TI - [Influence of glucocorticoids on thyroid stimulating hormone (TSH) secretion in man (author's transl)]. PMID- 4203403 TI - Editorial: Renal failure in tropical diseases. PMID- 4203405 TI - [Electrocardiographic-pathological correlation in 90 patients who died of chagasic cardiopathy]. PMID- 4203404 TI - Regeneration of the attachment apparatus on pulpless teeth denuded of cementum in the rhesus monkey. PMID- 4203395 TI - Moraxella, Acinetobacter, and the Mimeae. PMID- 4203407 TI - Potatoes and birth defects: summary. PMID- 4203406 TI - [Results of the prolonged treatment of simple osteoporosis with porcine calcitonin]. PMID- 4203408 TI - Investigations into the teratogenic potential of imperfect potatoes. PMID- 4203409 TI - Are potatoes teratogenic for experimental animals? PMID- 4203410 TI - [Modern radiotherapy]. PMID- 4203411 TI - [Diagnostic problems of Recklinghausen's disease (medico-genetic aspects)]. PMID- 4203412 TI - [Arthrography of the talocrural joint in ruptures of the ligaments]. PMID- 4203413 TI - [Use of the TSH releasing hormone in examination of the hypothalamo-hypophyseal thyroid system]. PMID- 4203414 TI - [Fluorescence serological studies on the appearance of Borna virus antigen in cell cultures from brain explants of infected rabbits]. PMID- 4203396 TI - Structure and synthesis of the ribosomal ribonucleic acid of prokaryotes. PMID- 4203415 TI - The origin of immunoglobulin-G in bovine tears. PMID- 4203416 TI - Analysis of C1 subcomponents in cell culture media of HeLa cells and diploid human fetal lung fibroblasts. PMID- 4203417 TI - [Pathogenic mycobacteria in dermatology (author's transl)]. PMID- 4203418 TI - Scanning the radiation field of a 25-MeV medical betatron using a new uniformity check system. PMID- 4203419 TI - Quantitative and qualitative aspects of the plasma protein binding of carbenoxolone, an ulcer-healing drug. PMID- 4203420 TI - Interaction of drugs with thyroid hormone binding sites. PMID- 4203421 TI - Influence of certain pesticides on microorganisms. Influence of DDT on the synthesis of the particular amino acids in Chlorella vulgaris and Anabaena cylindrica. PMID- 4203422 TI - Plasma proteins in the semen of bulls. PMID- 4203423 TI - Blood group homologues in orangutans and gorillas of the human Rh-Hr and the chimpanzee C-E-F systems. PMID- 4203424 TI - Feeding levels and feeding sites of red colobus (Colobus badius tephrosceles) in the Gombe National Park. PMID- 4203425 TI - The distribution of the white-collared mangabey, Cercocebus torquatus, in Nigeria. PMID- 4203427 TI - [Behavioral modification of Papio papio by feeding him in its natural environment (author's transl)]. PMID- 4203426 TI - Changes in the sexual behaviour of male rhesus monkeys (M. mulatta) at puberty. Comparisons with the behaviour of adults. PMID- 4203429 TI - [Scanning electron microscopic study of the gastrointestinal tract. 3. 3-Di mentional observation of the mucosal surface]. PMID- 4203428 TI - In vitro fertilization of human ova and blastocyst transfer. An invitational symposium. PMID- 4203430 TI - Advances in rehabilitative care lag behind progress in managing episodic disease. PMID- 4203431 TI - Pyrolysis-gas-liquid chromatography of fungi: numerical characterization of species variation among members of the Aspergillus glaucus group. PMID- 4203432 TI - [A case of canine babesiosis in Denmark (author's transl)]. PMID- 4203434 TI - Nurse autonomy and accountability in organized nursing services. PMID- 4203433 TI - Proceedings: Netherlands Society for Microbiology meeting at Utrecht on 2 May 1973. Sporulation of anaerobic sporeformers. PMID- 4203435 TI - [Osteo-articular complications in septicemia due to Pseudomonas aeruginosa]. PMID- 4203436 TI - [Biosynthesis of diacetyl by lactic acid bacteria]. PMID- 4203437 TI - Concomitant occurrence of neurofibromatosis and carcinoid of the intestine. PMID- 4203439 TI - [Use of protein in oncological patients]. PMID- 4203438 TI - [Clinical significance of detecting Australia antigen (HAA) in chronic hepatitis and cirrhosis of the liver]. PMID- 4203440 TI - [Hepatitis-bound Australia antigen and specific antiviral immunity in children with chronic diseases]. PMID- 4203442 TI - [Alpha2-macroglobulin in the nephrotic syndrome]. PMID- 4203441 TI - [Emergency conditions in diabetes mellitus]. PMID- 4203443 TI - [Is the mind tabu?]. PMID- 4203445 TI - Scanning electron microscope observations on the spore of Nosema apis Zander. PMID- 4203444 TI - The histocompatibility complex of rhesus monkeys. I. Serology and genetics of the RhL-A system. PMID- 4203446 TI - Carcinoma of the ovary. Radiation therapy experience. PMID- 4203447 TI - Mammary nodular hyperplasia in intact rhesus monkeys. PMID- 4203448 TI - Besnoitia bennetti in two Mexican burros. PMID- 4203449 TI - [Use of thiophosphamide in the treatment of patients with bronchial asthma]. PMID- 4203450 TI - Prognosis of depressed skull fracture. PMID- 4203451 TI - Letter: Spinal anesthesia and ephedrine in pregnant monkeys. PMID- 4203452 TI - The presence and possible significance of cross-reactive antigens in Rhizobium- legume associations. PMID- 4203453 TI - Proceedings: Netherlands Society for Microbiology meeting at Utrecht on 2 May 1973. Chemotaxis in microorganisms. PMID- 4203454 TI - Proceedings: Netherllands Society for Microbiology meeting at Utrecht on 2 May 1973. Environmental effects on bacterial wall synthesis. PMID- 4203455 TI - [Intraarticular fractures of distal tibia: results after 9 years (author's transl)]. PMID- 4203456 TI - Evaluation of 167Tm HEDTA as a bone scanning agent in humans and its comparison with 18F. PMID- 4203458 TI - A comparison of three in vivo assays for cell tumorigenicity. PMID- 4203457 TI - Intra-uterine infection and cord immunoglobulin M. II. Clinical analysis of infants with elevated cord serum immunoglobulin M. AB - Cord blood immunoglobulin M was measured in 3474 consecutive newborn infants. A group of 147 infants with elevated IgM values (>/=19.0 mg./100 ml.) were compared with 92 unselected newborn infants with normal IgM values. One infant with clinically unsuspected congenital rubella was detected in the study group while no cases of intra-uterine infection were found among the controls. A greater proportion of mothers in the study group had a history of viral infection. The study group also contained a larger number of mothers who might be considered to be at greater risk of infection with agents known to cause intra-uterine disease. Follow-up studies at 6 months of age revealed no differences between the two groups aside from an increased incidence of minor motor abnormalities in the study group. While it is recognized that infants with cord blood IgM levels truly in excess of 30 mg./100 ml. may represent a high-risk group with respect to proved or subclinical intra-uterine infection, it is concluded that routine cord blood screening for elevated IgM values is not a high-yield procedure for the detection of intra-uterine infection in our population. PMID- 4203459 TI - Strain-dependent teratogenic effects of 1-ethyl-1-nitrosourea in inbred strains of mice. PMID- 4203460 TI - The reaction between carcinoembryonic antigen and concanavalin A. PMID- 4203461 TI - Differing methodology and equations used in quantitating immunoglobulins by radial immunodiffusion--a comparative evaluation of reported and commercial techniques. PMID- 4203462 TI - Letter: Commercial immunodiffusion plates. PMID- 4203463 TI - Letter: Non-narcotic buffer for hemoglobin electrophoresis. PMID- 4203464 TI - [Generalized congenital listeria monocytogenes infection with fatal outcome (author's transl)]. PMID- 4203465 TI - [Caesarean section and perinatal mortality in small city hospital (author's transl)]. PMID- 4203466 TI - Injection technique for indocyanine green and sodium fluorescein dye angiography of the eye. PMID- 4203467 TI - Pharmacologic weakening of extraocular muscles. PMID- 4203468 TI - A correlation of anatomic and physiologic parameters in the ureter. PMID- 4203469 TI - The relationship of epididymitis to gonorrhea. PMID- 4203471 TI - Effect of soft tissues on radiographic measurements of the head. PMID- 4203470 TI - Snake venom toxins. The purification and amino acid sequence of toxin TA2 from Dendroaspis angusticeps venom. PMID- 4203472 TI - Pathologic response of gingiva to an amino acid increase. PMID- 4203473 TI - Pulp reaction to a polycarboxylate cement in monkeys. PMID- 4203474 TI - Nutritional status of children at Namitambo, Malawi. PMID- 4203475 TI - Influence of maximal vasodilatation on glucose and sodium blood-tissue transport in canine heart. PMID- 4203476 TI - Utilization of fructose by a unicellular blue-green alga, Anacystis nidulans. PMID- 4203477 TI - Immunosuppressive activity of a heat-stable factor associated with interferon. PMID- 4203478 TI - Mechanisms of ankle injury. PMID- 4203479 TI - Injuries of the ankle in children. PMID- 4203480 TI - Ankle injuries in athletes. PMID- 4203481 TI - Indications for fusion of the ankle. PMID- 4203483 TI - The use of peripheral veins for alimentation in paediatric patients. PMID- 4203482 TI - [Neuronal circuits involved in the physiopathology of parkinsonian syndromes]. PMID- 4203484 TI - Enteric duplications. PMID- 4203485 TI - A human IgA-myeloma protein with anti-streptococcal hyaluronidase (ASH) activity. PMID- 4203486 TI - Bovine fibrinogen-induced platelet factor 3 and acid phosphatase availability in human platelets. PMID- 4203487 TI - Chlorinated hydrocarbons in the Sargasso sea atmosphere and surface water. AB - Polychlorinated biphenyls (PCB), DDT, and chlordane concentrations were measured in air sampled from a tower on the south shore of Bermuda and in Sargasso Sea surface water approximately 80 to 320 kilometers south of Bermuda. The atmospheric chlorinated hydrocarbons appeared to be gaseous, and the DDT concentration was two orders of magnitude higher than previously reported particulate values. The PCB and DDT were enriched in the surface microlayer (150 micrometers) relative to their concentrations in water at a depth of 30 centimeters. Atmospheric residence times for PCB and DDT of 40 to 50 days, calculated from the concentrations in the air and water, are 20 times shorter than values previously estimated for DDT from rainfall and DDT production data. PMID- 4203488 TI - Nutritional significance of symbiotic bacteria in two species of hemoflagellates. AB - Symbiote-free strains of Blastocrithidia culicis and Crithidia oncopelti, obtained by chloramphenicol treatment, were compared nutritionally with normal, symbiote-containing strains. The symbiotic bacteria spare the flagellates requirements for exogenous hemin and for other nutritional factors present in liver extract. PMID- 4203489 TI - Cerebroside antibody inhibits sulfatide synthesis and myelination and demyelinates in cord tissue cultures. AB - Antiserum to cerebroside was prepared in rabbits by injection of cerebroside together with bovine serum albumin in complete Freund's adjuvant. When applied to cultures of embryo mouse spinal cord at explantation, this antiserum inhibited sulfatide synthesis and myelination; when applied to myelinated cultures it inhibited sulfatide synthesis and produced demyelination. Complement fixation assays also show antibody to cerebroside in serums from rabbits with experimental allergic encephalomyelitis induced by injection of whole white matter. Absorption of such serum with cerebroside abolishes the inhibiting and demyelinating activities. PMID- 4203490 TI - Leptospirosis in Philippine monkeys. PMID- 4203491 TI - Ecological distribution of blood parasites in some arboreal rodents. PMID- 4203492 TI - Sarcocystis from rats of Central Java. PMID- 4203493 TI - Relationship between liver weight and body weight in normal monkeys and dogs. PMID- 4203494 TI - Distribution and metabolism of DDT, carbaryl and methyl parathion in S-and R strains of Spodoptera littoralis (Boisd). PMID- 4203495 TI - The administration of monosodium L-glutamate to neonatal and pregnant rhesus monkeys. PMID- 4203496 TI - Serum immunoglobulin and complement levels relative to renal homotransplant rejection and patient survival. A retrospective study. PMID- 4203497 TI - Infarction of spinal cord and medulla oblongata caused by fibrocartilaginous emboli. Report of a case. PMID- 4203498 TI - Ultrastructural and biochemical study of benign ganglioneuroma. PMID- 4203499 TI - "Vaso-muscular mediadysplasia" of the arteria vertebralis. PMID- 4203500 TI - [The ultrastructure of the atrophic adrenal cortex in dissociated secondary adrenocortical insufficiency (author's transl)]. PMID- 4203501 TI - [Electron-microscope examination on histogenesis of uterine angiomatosis- endolymphatic stromal myosis (author's transl)]. PMID- 4203502 TI - Case report: Primary (autoimmune?) parathyroiditis. PMID- 4203503 TI - [Viral hepatitis (author's transl)]. PMID- 4203504 TI - Effects of insulin on glucose metabolism in vascular and intestinal smooth muscle. PMID- 4203506 TI - Standardization of test-negative cream for Brucella milk ring test. PMID- 4203505 TI - The appearance of some blood-bourne substances during human pregnancy. PMID- 4203507 TI - Efficacy of EDTA-tris-lysozyme lavage in the treatment of experimentally in induced Pseudomonas aeruginosa cystitis in the dog. PMID- 4203508 TI - Myocardial contractility in conscious rhesus monkeys: a method for long-term study. PMID- 4203510 TI - Parenteral nutrition by total intravenous feeding. PMID- 4203509 TI - Childhood, juvenile, and adult cerebral lipidoses. Are these different nosological entities? PMID- 4203512 TI - Biological production of 5-methylthioribose. PMID- 4203511 TI - Toxic and immunological differences among lipopolysaccharides from Thiobacillus ferrooxidans grown autotrophically and heterotrophically. PMID- 4203513 TI - The physiology of teichoic acid deficient staphylococci. PMID- 4203514 TI - The effect of thyroxine and triiodothyronine on bacterial growth. PMID- 4203515 TI - Alkaline phosphatase of Pseudomonas aeruginosa: the mechanism of secretion and release of the enzyme from whole cells. PMID- 4203516 TI - Solitary mastocytoma of infancy. PMID- 4203517 TI - The problem of bacteriologically contaminated infant formulas in a newborn nursery. PMID- 4203518 TI - Plasma norepinephrine and epinephrine in untreated diabetics, during fasting and after insulin administration. PMID- 4203519 TI - [Nursing aspects in epilepsy]. PMID- 4203520 TI - Lipid and enzyme changes in the blood and liver of monkeys given butylated hydroxytoluene and butylated hydroxyanisole. PMID- 4203521 TI - The formation of carcinogenic nitroso compounds from nitrite and some types of agricultural chemicals. PMID- 4203522 TI - Studies on the uridine diphosphate-galactose: lipopolysaccharide galactosyltransferase reaction using a fatty acid mutant of Escherichia coli. PMID- 4203523 TI - Protein synthesis with messenger ribonucleic acid fractions from membrane-bound and free liver polysomes. Translation characteristics of liver polysomal ribonucleic acids and evidence for albumin production in a messenger-dependent reticulocyte cell-free system. PMID- 4203524 TI - Use of benzamidine to prevent the destruction of thyrotropin-releasing hormone (TRH) by blood. PMID- 4203525 TI - Thyroglobulin defect in a human congenital goiter. PMID- 4203526 TI - Effect of synthetic luteinizing hormone-releasing hormone (LH-RH) on the release of gonadotropins in hypophyso-gonadal disorders of children and adolescents. 3. Hypopituitarism. PMID- 4203527 TI - Secondary hypopituitarism: evidence for continuing regulation of hormone release. PMID- 4203528 TI - Role of central monitoring of efference in short-term memory for movements. PMID- 4203530 TI - Isolation of cores from hepatitis B Dane particles. PMID- 4203529 TI - Induction of leukemoid disease in mice by Mycoplasma fermentans. PMID- 4203531 TI - Correspondence: Culture of Neisseria gonorrhoeae. PMID- 4203532 TI - Congenital toxoplasmosis. Fetal synthesis of oligoclonal immunoglobulin G in intrauterine infection. PMID- 4203533 TI - [Blood rituals]. PMID- 4203534 TI - [Life saver in congenital blood disorders]. PMID- 4203535 TI - [Hepatitis is spreading. Is drug abuse to blame?]. PMID- 4203536 TI - SOS--traffic accident. PMID- 4203537 TI - [Can blood preservatives make you ill?]. PMID- 4203538 TI - [Autologous blood transfusion following surgical intervention]. PMID- 4203539 TI - [Radiology. II. Nursing in the radiation clinic. Tasks and duties]. PMID- 4203540 TI - [Anesthesia and intensive therapy]. PMID- 4203541 TI - [Psychological stress for the child in the hospital. II]. PMID- 4203542 TI - [Prevention and health resort treatment of respiratory tract diseases]. PMID- 4203543 TI - [Respiration and health]. PMID- 4203544 TI - [Pulmonary emphysema in old age]. PMID- 4203546 TI - [Radiology. III. Physical basis of the action of ionizing radiation]. PMID- 4203545 TI - [Anesthesia and intensive therapy. II. Preparation for anesthesia and anesthesia induction]. PMID- 4203547 TI - [Hospitalization of the child in the mother's presence]. PMID- 4203548 TI - Activation of hepatic microsomal glucuronyl transferase by bilirubin. PMID- 4203549 TI - Block of oxytocin-induced parturition and oviposition by prostaglandin inhibitors. PMID- 4203550 TI - [Radiotherapy of cancer of the mucous membrane of the hard palate]. PMID- 4203551 TI - [Relative biological efficacy of fast electrons in different sections of the tissue-equivalent phantom]. PMID- 4203552 TI - [Collimator with shed cover for forming the beam of electrons of betatron B5M 25]. PMID- 4203553 TI - [Chemoradiation treatment of neglected forms of malignant neoplasms]. PMID- 4203554 TI - Clinical pharmacology of carbenicillin and gentamicin in the neonate and comparative efficacy with ampicillin and gentamicin. PMID- 4203555 TI - The influence of hexachlorophene scrubs on the response to placebo or penicillin therapy in impetigo. PMID- 4203556 TI - Crystal formation: a new complication of total parenteral nutrition. PMID- 4203557 TI - Increase in the plasma concentration of free tryptophan caused by probenecid in humans. PMID- 4203558 TI - [Amyloidosis: an immunoproliferative disease]. PMID- 4203559 TI - [Osseous and proeosseous structures in calculi of the urinary tract]. PMID- 4203561 TI - Effect of gold salts and antimalarials on the rheumatoid factor in rheumatoid arthritis. PMID- 4203560 TI - [Current concepts on the feeding of low birthweight infants]. PMID- 4203563 TI - G.C. culture evaluation in a community health center. A study of 870 cases. PMID- 4203562 TI - Estriol metabolism in the baboon: analysis of urinary and biliary metabolites. PMID- 4203564 TI - Action of some metal ions, EDTA, and heated milk on the milk-clotting process of Penicillium citrinum rennin-like enzyme. PMID- 4203565 TI - [Ecology of fermentation sarcinas Sarcina ventriculi and Sarcina maxima]. PMID- 4203566 TI - The role of fat as a calorie course in parenteral nutrition. PMID- 4203567 TI - [Sterilization of transplantation material]. PMID- 4203568 TI - [Blood groups in octuplets]. PMID- 4203569 TI - Heavy metals--toxicity and environmental pollution. PMID- 4203570 TI - A survey of naturally occurring chelating ligands. PMID- 4203571 TI - [Diagnosis and treatment of hypercalcemia]. PMID- 4203572 TI - Clinical effectiveness of lividomycin on urinary tract infections: evaluation with double-blind method. PMID- 4203573 TI - Halofenate: an effective hypolipemia- and hypouricemia-inducing drug. PMID- 4203574 TI - Use of lorazepam in treating patients with neurotic and somatized psychovegetative symptoms. PMID- 4203575 TI - Molindone: a crossover evaluation of capsule and tablet formulations in severely ill schizophrenic patients. PMID- 4203576 TI - Amoxapine and imipramine: a double-blind study in depressed patients. PMID- 4203577 TI - A method of pooling data of different rating scales. PMID- 4203578 TI - Homoeosis in Drosophila. I. Complementation studies with revertants of Nasobemia. AB - A number of homoeotic mutants have been localized to the proximal right arm of chromosome 3 of Drosophila melanogaster. These include seven alleles of Antennapedia (Antp), which is associated with a transformation of antennae into legs; Nasobemia (Ns), which causes the same phenotype as Antp but was considered by Gehring (1966) not to be an allele; and three genes causing a transformation of second and third legs into first legs: Extra sex comb (Scx), Polycomb (Pc), and Multiple sex comb (Msc.). The alleles of Antp and Scx share a common recessive lethal effect, and Pc maps 0.2-0.3 units to the left of Scx.-In the present investigation, rearrangements associated with the reversion of Ns suggest that its cytological location is in or just distal to salivary chromosome doublet 84B1-2. Although Ns is viable when homozygous, four of its revertants share a common recessive lethal effect. These revertants fail to complement the recessive lethality of Antp(B) and Scx. Furthermore, they show a complex pattern of functional interaction with Pc and with Humeral (Hu), a dominant mutation associated with a rearrangement with one breakpoint just distal to 84B1-2. Finally, analysis of a revertant of Msc indicates that Msc is also located very close to 84B1-2. It is concluded that Ns and Scx are alleles of Antp. Pc shows many functional similarities to the Antp locus, but is probably not allelic. Evidence is presented that these dominant homoeotic genes are neomorphic in nature. PMID- 4203579 TI - The interaction of two complex loci, zeste and bithorax in Drosophila melanogaster. AB - It has been found that certain alleles of the zeste locus (z(a) 1-1.0) have no phenotype of their own, but interact with certain alleles at the bithorax locus (bx 3-58.8). This interaction takes the form of an enhancement of the homeotic bx phenotype to a more extreme form-i.e., the metathorax is transformed into mesothorax in varying degrees depending on the bx allele used. This enhancement is somewhat reminiscent of the transvection effect described by Lewis (1954). The characterization of the interaction thus far has shown that the enhancement only effects bx alleles which arise spontaneously, whereas the origin of the z(a) allele is unimportant. The gene claret nondisjunctional was used for the production of gynandromorphs which showed that the enhancing ability of z(a), like the eye pigment change caused by z, is autonomous. The enhancement of one specific allele (bx(34e)), which is temperature-sensitive, has allowed a delineation of the temperature-sensitive period of the bithorax locus to a period extending from the middle of the second larval instar to the middle of the third larval instar. These results, as well as those of other enhancer and suppressor systems in Drosophila, have revealed the possibility of the involvement of heterocyclic compounds in the control of cell determination and fate in Drosophila melanogaster. PMID- 4203580 TI - Patterns of gene variation in central and marginal populations of Drosophila robusta. AB - The central and marginal populations of D. robusta differ greatly in the level of inversion polymorphism; the marginal populations are monomorphic or nearly so and the central populations are highly polymorphic. This paper presents the frequencies of alleles at forty gene loci in various populations of D. robusta, studied by electrophoresis of proteins and enzymes. Population samples were obtained from eight widely separated populations of D. robusta which included the central, the extreme marginal and the intervening populations between the center and the margins. We find that the proportion of polymorphic loci and average heterozygosity per individual is slightly higher in the marginal populations than the central populations. In D. robusta on an average, 39% of the loci are polymorphic and the average proportion of loci heterozygous per individual is 11%. A breakdown of loci in three categories, viz, hydrolytic enzymes and some other enzymes, larval proteins and glycolytic and Kreb's cycle enzymes, shows that in all populations the level of polymorphism is highest in the hydrolytic enzymes, intermediate in larval proteins and least in the glycolytic and Kreb's cycle enzymes. On the average, the proportion of loci heterozygous per individual for three groups of loci is: hydrolytic enzymes and others (.164), larval proteins (.115) and glycolytic and Kreb's cycle enzymes (.037). We also observe that in all populations the level of polymorphism on the X chromosome is far less than the expected 38%; in salivary gland cells the euchromatic length of the X chromosome is 38% of the entire genome. Lower levels of polymorphism for the X chromosome loci are explained due to low probability of balanced polymorphisms for the X-linked loci since the conditions for establishment of balanced polymorphism for X-linked loci are more restrictive than for the autosomal loci. The polymorphic loci can be grouped according to pattern of allele frequencies in different populations as follows: (1) The allele frequencies are similar in all populations at the XDH, Pep-1 and Hex-1 loci. (2) The alleles at the Est-1, Est 2, Amy loci and the AP-4(1.0) and the LAP-1(.90) alleles show north south clinal change in frequency. (3) There is north south and east west differentiation at the Pt-5, Pt-8 and Pt-9 loci and the allele AP-4(.81). (4) Polymorphism at loci such as Fum, B.Ox, Hex-8, Pep-2 and Pep-3 are restricted to only one or two of the populations. (5) Allele frequencies at the MDH and ODH loci fluctuate between populations. (6) Allele frequencies at many polymorphic loci such as Est-1, Est 2, LAP-1, AP-4, Pt-5, Pt-8, Pt-9, Pt-16, MDH, Fum change clinally within a gene arrangement. The pattern of gene variation in D. robusta is very complex and cannot be easily explained due to migration of neutral alleles between once isolated populations or to semi-isolation of neutral alleles. The observations of the pattern of allele variation in different populations, high levels of polymorphism in the marginal populations which have small population size and low levels of polymorphism of the X chromosome loci all support the argument in favor of balancing selection as the main mechanism for the maintenance of these polymorphisms. Environmental factors must play a role in the maintenance of a great deal of these polymorphisms, since we observe clinal allele frequency changes even within a given inversion type. PMID- 4203581 TI - Inherited biochemical variation in Drosophila melanogaster: noise or signal? I. Single-locus analysis. AB - A study was conducted using small effective population size as an experimental design to test selective neutrality of seven isozyme polymorphisms. Loci varied as to the degree to which the decay of heterozygosity over 21 generations was retarded. Selection for heterozygotes, overdominance, is implicated for at least four of seven loci. Of these ADH gave the largest heterozygote excess in the presence of inbreeding. An interaction between the small population size treatment and excess heterozygosity suggests that (1) the loci studied may be selectively neutral and linked to other loci which are under the influence of selection or (2) the selection coefficients for the loci studied are not independent of the background genotype. In either case four of the seven enzymes studied are signaling the operation of selection. The problem of distinguishing the effect of a single marker from that of a chromosome segment is emphasized. The identification of the genetic unit of selection is crucial to any interpretation of the meaning of enzyme polymorphisms. PMID- 4203582 TI - [Siderinuria caused by deferoxamine. II. The siderinuric increment obtained by association with ascorbic acid]. PMID- 4203583 TI - [Analysis of the lipo-glycoprotein components of sheep erythrocyte membranes using disc electrophoresis]. PMID- 4203584 TI - [Modification of erythrocyte lipids in rats maintained on a steatogenic diet]. PMID- 4203585 TI - [Relationships between 5-hydroxytryptamine (serotonin), dense bodies of platelets and bone marrow megakaryocytes]. PMID- 4203586 TI - [The velocity of thalassemic erythrocyte lysis in hypotonic electrolyte solutions]. PMID- 4203587 TI - [Determination of the alpha-beta globin quotient, of possible use in population studies]. PMID- 4203588 TI - [A rare case of combined factor V and factor VIII deficiency]. PMID- 4203589 TI - [Immunologic determination of prothrombin in the normal newborn infant]. PMID- 4203590 TI - [Cyclic thrombopenia or "periodic platelet dysgenesis" or "periodic dysthrombocytopoiesis" in a female patient]. PMID- 4203591 TI - [Determination of plasma cell esterases]. PMID- 4203592 TI - [The use of lysozyme determination in myeloma]. PMID- 4203593 TI - [Somatotropin deficiency in Fanconi's anemia]. PMID- 4203594 TI - [Hemolytic congenital non-spherocytic anemia with PK deficiency: destruction of chromium-51 labeled erythrocytes in the spleen]. PMID- 4203595 TI - [Immunological data during the course of childhood reticuloendotheliosis]. PMID- 4203596 TI - [The problem of the "non-secreting" myeloma]. PMID- 4203597 TI - Diphthericin types, bacteriophage types and serotypes of Corynebacterium diphtheriae strains isolated in Australia. AB - A dipthericin typing scheme has been constructed using 441 strains of Corynebacterium diptheriae isolated in eastern Australia from 1962 to 1971. Ten types have been distinguished using seven strains of C. diphtheriae and two strains of C. belfanti as indicators of the diphthericins produced by the newly isolated strains. Strains grouped into types L2, L3 and L3a were found only in Melbourne and types L1 and L4 were predominant in Sydney. Type L5 strains were isolated intermittently throughout the period of study and were found in all eastern states. Numerical analysis of the characteristics of the strains suggests that associations exist between, on the one hand, diphthericin type and, on the other hand, bacteriophage type, serotype and biochemical activity. PMID- 4203599 TI - The effect of collagenase-like peptidase from rat testis and clostridial collagenase A on the rat seminal vesicle secretion and its coagulation. PMID- 4203598 TI - Variation among strains of Coynebacterium diphtheriae during an outbreak in a restricted environment. AB - Strains of Corynebacterium diphtheriae isolated from a small outbreak in the restricted environment of a Mental Hospital were examined. All belonged to one serotype, but there was marked variation in diphthericin type, in sensitivity to bacteriophages and in the minor antigens possessed. One strain was non-virulent and laboratory-produced variants of this non-virulent strain showed changes in some of the characteristics used in the identification and typing of the organism, such as diphthericin type, sensitivity to bacteriophages and diphthericins, virulence, starch fermentation and, to a lesser extent, in antigenic structure. The epidemiological and experimental findings are consistent with the hypothesis that the strains isolated, both in the hospital and in the laboratory, were derivatives of a single parent and the mechanism of some of the variations could be related to changes in some structural component such as the cell membrane or the cell wall. PMID- 4203600 TI - Stimulation of actinomycin D-binding to eutherian sperm chromatin by reduction of disulphide bonds. PMID- 4203601 TI - Electron microscopy of human vaginal epithelium under normal and experimental conditions. PMID- 4203602 TI - Posttraumatic ossification of the myocardium. PMID- 4203603 TI - [Late damage after Rh-erythroblastosis, ABO-erythroblastosis and hyperbilirubinemia in the neonate (author's transl)]. PMID- 4203604 TI - [Double diffusion in agar gel test for detection of Toxoplasma antibody]. PMID- 4203605 TI - Malaria in Vietnam (I Corps sector): review of 214 cases including EEG patterns on 19 acutely ill patients. PMID- 4203606 TI - Management in military blood banking for conservation of blood resources: new aspects concerning the blood donor base. PMID- 4203607 TI - Case for diagnosis: phaeosporotrichosis. PMID- 4203608 TI - Perspectives in renovascular hypertension. PMID- 4203609 TI - Blast injury of the ear: treatment and evaluation. PMID- 4203610 TI - Free-living wild animal studies: a stimulus to zoonoses research. PMID- 4203611 TI - Factors related to the retention of naval flight surgeons. PMID- 4203613 TI - Spontaneous rupture of hypernephroma: case report. PMID- 4203612 TI - Maxillofacial rehabilitation in South Vietnam. PMID- 4203614 TI - School counselor: neglected asset in Department of Defense schools. PMID- 4203615 TI - [Proceedings: Classification and clinical symptomatology of cerebral aneurysms]. PMID- 4203616 TI - [The function of the hypothalamus and its clinical implications]. PMID- 4203617 TI - [Contribution of immunoprecipitation tests to the diagnosis of hydatidosis]. PMID- 4203618 TI - [The prostaglandins]. PMID- 4203619 TI - [Phenformin in juvenile diabetes mellitus]. PMID- 4203620 TI - Synkavit. Radiosensitizing agent in prostatic carcinoma. PMID- 4203621 TI - Histocompatibility testing in intrafamilial renal transplantation. PMID- 4203623 TI - Circulatory effects of splenectomy in the horse. 3. Effect on pulse-work relationship. PMID- 4203622 TI - [Use of ultrasound for increasing the activity of arbovirus antigens in serological reactions in vitro]. PMID- 4203624 TI - Milk ejection in primiparous heifers in the presence of their calves. PMID- 4203625 TI - [Oxygen-binding curves of blood in varions domestic mammals in relation to temperature]. PMID- 4203626 TI - [Quantitative and qualitative studies on porcine mast cells]. PMID- 4203627 TI - The determination of testosterone in the plasma of calves by radioimmunoassay. PMID- 4203628 TI - The effects of pitocin and hysterectomy on growth and involution of the corpus luteum of the rabbit. PMID- 4203629 TI - Effect of hysterotomy in ewes at different stages of gestation on consequent fertility. PMID- 4203630 TI - [Comparative histological and immunological studies on immunologically defective hens. I. Hormonally bursectomized hens]. PMID- 4203631 TI - [Comparative histological and immunological studies on immunologically defective chickens. II. Genuine dysgammaglobulinemic chickens]. PMID- 4203632 TI - Localization of measles antibody and inhibitor activity in fractions of human sera at different stages of the disease, and sera of animals immunized with measles virus. I. Dynamics of increase in measles antibody activity and its localization in children sera after natural infection. PMID- 4203633 TI - II. Primary and secondary immunological response of experimental animals to attenuated and nonattenuated measles virus. PMID- 4203634 TI - Experimental studies on attenuated measles virus. PMID- 4203635 TI - [Tuberculosis and cutaneous mycobacterium infections]. PMID- 4203636 TI - [Lipoma of the temporal region with cortical malformation and epilepsy. Clinicopathological study (author's transl)]. PMID- 4203637 TI - Ontogeny of squirrel monkey calls under normal conditions and under acoustic isolation. PMID- 4203638 TI - Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats. PMID- 4203639 TI - Urinary excretion of the mycotoxin, sterigmatocystin by vervet monkeys. PMID- 4203640 TI - [Use of human anti-Rh(D) immunoglobulin]. PMID- 4203641 TI - Evidence of biological kinship using red cell enzyme polymorphisms to supplement the blood groups. PMID- 4203642 TI - Antitumor activity of constituents of Pseudomonas aeruginosa. PMID- 4203643 TI - Dietary appraisal of West Bengal pre-school children and its effect on growth and nutrition. PMID- 4203644 TI - A histologic follow-up study of free autogenous skin grafts to the alveolar ridge in humans. PMID- 4203645 TI - The capacity of the parotid glands to concentrate 99mTc from plasma, used as a function test. PMID- 4203646 TI - Operative procedures in periapical surgery with contempraneous root filling. PMID- 4203647 TI - A study of failures after endodontic surgery by radiographic, histologic and stereomicroscopic methods. PMID- 4203648 TI - A note on the origin of keratocysts of the jaws. PMID- 4203649 TI - Occurrence of focal epithelial hyperplasia among Amerindians in Ecuador. PMID- 4203650 TI - A histologic study of experimentally produced intra-oral odontogenic fistulae in monkeys. PMID- 4203651 TI - Effect of pupal necrosis upon periodontal healing after surgical injury in rats. PMID- 4203652 TI - Remarkable recurrence of a keratocyst in a bone-graft. PMID- 4203653 TI - The treatment of ankylosis in children. PMID- 4203654 TI - Influence of mandibular third molars on related supporting tissues. PMID- 4203656 TI - Lymphangiosarcoma of the gingiva. PMID- 4203655 TI - Five cases of hypophosphatasia with dental findings. PMID- 4203657 TI - New metabolic products of Aspergillus flavus. 3. Biosynthesis of asperentin. PMID- 4203658 TI - Chloroplast ribosomal RNA genes in the chloroplast DNA of Euglena gracilis. PMID- 4203659 TI - A test for nucleotide sequence homology. PMID- 4203660 TI - Formation of rings from Drosophila DNA fragments. PMID- 4203661 TI - Stability and fine structure of eukaryotic DNA rings in formamide. PMID- 4203662 TI - Proteins in fluid from non-keratinizing jaw cysts. 1. Separation patterns on cellulose acetate membranes and percentage distribution of the electrophoretic fractions. PMID- 4203663 TI - Activity levels of some oxidoreductases of carbohydrate metabolism in leukoplakic and normal human buccal epithelium. PMID- 4203664 TI - Thymidine uptake and cell migration in cheek epithelium of zinc-deficient rats. PMID- 4203665 TI - [Cardiac catecholamines in stress situations]. PMID- 4203667 TI - [Properties of cytoplasmic membranes of thermophilic bacteria]. PMID- 4203666 TI - [Comparative study of microbial protease complexes]. PMID- 4203668 TI - [Combined effect of chemical compounds and gamma-radiation on cells of the blue green alga Anacystis nidulans]. PMID- 4203669 TI - [Fine structure, biological properties and intracellular development of phage PBS21 in Bacillus subtilis cells]. PMID- 4203670 TI - [Effect of water activity on the development of microorganisms in fine-pored systems (kaolinite)]. PMID- 4203671 TI - Total parenteral hyperalimentation versus conventional techniques. PMID- 4203672 TI - [The Ewing sarcoma (41 cases) (author's transl)]. PMID- 4203673 TI - [Experimental caries and human caries]. PMID- 4203674 TI - Amyloid fibril protein subunit, "protein AS": distribution in tissue and serum in different clinical types of amyloidosis including that associated with myelomatosis and Waldenstrom's macroglobulinamia. PMID- 4203675 TI - The enrichment of T-cell functions in a lymphocyte population by anti immunoglobulin columns. PMID- 4203676 TI - Disulfide bonds of human IgM: differential sensitivity to reductive cleavage. PMID- 4203677 TI - [Clinical value of the complex determination of the drug resistance of Mycobacterium tuberculosis]. PMID- 4203678 TI - [Immunochemical study of fibrinogen disintegration products in the blood serum of patients with rheumatism]. PMID- 4203679 TI - [Inoculability of Mycobacterium tuberculosis from milk]. PMID- 4203680 TI - [Determination of the virulence of Listeria]. PMID- 4203682 TI - [Comparative evaluation of express methods for syphilis in cadaveric blood taking into account pathologicoanatomical data]. PMID- 4203681 TI - [The XXXXY syndrome. Report of 7 new cases and review of the literature (author's transl)]. PMID- 4203684 TI - [Biological function of Clostridium tetani toxin (ecological and evolutionary aspects)]. PMID- 4203683 TI - [Model of the vertebrate nervous system based largely on disinhibition. Key role of the GABA system]. PMID- 4203685 TI - [Comparative study of seizure activity in monkeys and rabbits]. PMID- 4203686 TI - Fracture healing controlled by 87mSr uptake. PMID- 4203687 TI - Stimulation of TSH release and glucose oxidation in pituitaries from thyroidectomized rats by thyrotropin releasing factor (TRF). PMID- 4203688 TI - Current status of the cholesterol hypothesis. PMID- 4203690 TI - [Changes in the spinal cord in so-called spinal ossifying arachnoiditis]. PMID- 4203689 TI - Chronic meningococcemia in childhood. Case report and review of the literature. PMID- 4203691 TI - [Occlusive disorders of ischiopubic synchondrosis with reference to pathologic hip findings]. PMID- 4203692 TI - Surveillance of elderly hospital patients for pulmonary tuberculosis. AB - A restrospective study of pulmonary tuberculosis in a general hospital showed that the diagnosis had been frequently overlooked in the middleaged or elderly because the patient also suffered from a more acute condition which preoccupied the attention of the doctor. The commonest error was to discount chest x-ray abnormalities by omitting sputum culture or serial radiography.Surveillance was carried out on all patients aged 60 or over admitted to a large general hospital whose routine chest radiograph showed signs of possible pulmonary tuberculosis whether apparently active or inactive. Three sputum samples from each patient were examined for Mycobacterium tuberculosis without reference to the clinical presentation. In a nine-month period six out of 81 patients proved to have active pulmonary tuberculosis (7.4%). It is suggested that this may be a useful method of screening the elderly hospital population for pulmonary tuberculosis. PMID- 4203693 TI - Assessment of indirect haemagglutination procedures for the serological diagnosis of bovine brucellosis. PMID- 4203694 TI - Assessment of fluorescent antibody absorption procedures for differentiation of the serological response to Yersinia enterocolitica serotype IX and Brucella abortus in cattle. PMID- 4203695 TI - The triiodothyronine and thyroxine response to thyrotrophin-releasing hormone in the assessment of the pituitary-thyroid axis. PMID- 4203696 TI - Plasma thyrotrophin and its response to thyrotrophin releasing hormone in endemic goitre. PMID- 4203697 TI - Attachment formation and separation in heterosexually naive preadult rheus monkeys (Macaca mulatta). PMID- 4203699 TI - Isolation and properties of mutants of the FP2 sex factor of Pseudomonas aeruginosa. PMID- 4203698 TI - [Gingival reaction to the contact with dental materials]. PMID- 4203700 TI - Genetic and environmental control of a continuous trait, abnormal abdomen, in Drosophila melanogaster. PMID- 4203701 TI - Genetic differences between populations of Drosophila melanogaster for a quantitative trait. I. Laboratory populations. PMID- 4203702 TI - Genetic differences between populations of Drosophila melanogaster for a quantitative trait. II. Wild and laboratory populations. PMID- 4203703 TI - [Method of estimating the irradiation of critical organs in man in case of body entry of dissociative fragments]. PMID- 4203704 TI - Mechanism and kinetics of the Haldane effect in human erythrocytes. PMID- 4203705 TI - Kinetic analysis of calcium transport across the placenta. PMID- 4203706 TI - In vivo regional cerebral blood volume by x-ray fluorescence: validation of method. PMID- 4203707 TI - A bidirectional projection between the gracile nucleus and the cerebellum in the dog? An experimental study with tigrolysis and axonal degeneration methods. PMID- 4203708 TI - Peripheral and thoracic duct lymphocyte blastogenesis by T cell specific mitogens in the rhesus monkey. PMID- 4203709 TI - Essential fatty acid studies in primates linolenic acid requirements of capuchins. PMID- 4203710 TI - Experimental placental detachment in the rhesus monkey: changes in villous ultrastructure. PMID- 4203711 TI - A comparative study of platelet aggregation in primates. PMID- 4203712 TI - Some factors affecting the occurence of lead poisoning in captive primates. PMID- 4203713 TI - Mechanical properties of the primate thorax. PMID- 4203714 TI - Learning in monkeys fed elevated amino acid diets. PMID- 4203715 TI - Commensals and parasites of African baboons (Papio cynocephalus L. 1766) captured in Rift Valley Province of central Kenya. PMID- 4203717 TI - Eruption sequence of the deciduous dentition of Papio cynocephalus. PMID- 4203716 TI - Lipid levels in serum, liver and aorta of the vervet monkey. PMID- 4203718 TI - Unilateral renal aplasia in the baboon. PMID- 4203719 TI - The effects of arachidonic acid, prostaglandin E2 and prostaglandin F2alpha on the longitudinal stomach strip of the rat. PMID- 4203720 TI - Evaluation of the hypothermic action of tetrahydrocannabinols in mice and squirrel monkeys. PMID- 4203721 TI - Increase in hepatic blood flow and d-propranolol clearance by glucagon in the monkey. PMID- 4203722 TI - Device for the formation of wells in agar gel. PMID- 4203723 TI - Medium for the propagation and assay of lactic and other phages. PMID- 4203724 TI - [Upper stomach diverticula]. PMID- 4203725 TI - [Parenteral hypernutrition in seriously ill surgical patients. Methods, technic, indications and complications]. PMID- 4203726 TI - [Acid-base equilibrium of the human body--theoretical and clinico-diagnostic aspects. XIV. Disturbances of acid-base equilibrium in diabetes]. PMID- 4203727 TI - [Detection of Au-SH antigen with the latex (L-HAA) test in cases of viral hepatitis and rheumatoid arthritis]. PMID- 4203728 TI - [Erythrocytic carbonic andhydrase isoenzymes in normal subjects and in patients with blastomas and hemopathies]. PMID- 4203729 TI - [Facial spasm and photosensitive epilepsy in Papio papio]. PMID- 4203730 TI - IgM serum agglutinators. PMID- 4203731 TI - Characterization of subclass-related F(ab)2, Fab-c and Fch fragments obtainined by short papain digestion of human IgG myeloma proteins. PMID- 4203732 TI - Instrumental (operant) conditioning of visceral and autonomic functions. PMID- 4203733 TI - [Therapy of cardiac edema with a combination of hydrochlorthiazide and amiloride HCl (author's transl)]. PMID- 4203734 TI - The effect of serotonin on cerebral and extracerebral blood flow with possible implications in migraine. PMID- 4203736 TI - Studies on electron transport associated with photosystem I. 3. The reduction sites of various Hill oxidants in the photosynthetic electron transport system. PMID- 4203735 TI - Ossifications as a reaction on metal implants. PMID- 4203737 TI - A new polyamine carrier for the immobilization of proteins. Water-insoluble derivatives of pepsin and trypsin. PMID- 4203739 TI - Soya-bean lipoxygenase: an iron-containing dioxygenase. PMID- 4203738 TI - Soyabean lipoxygenase: an iron-containing enzyme. PMID- 4203740 TI - Solubilization and characterization of hepatic bilirubin UDP glucuronyltransferase. PMID- 4203742 TI - [Changes in serum immunoglobulin concentration in splenectomized patients]. PMID- 4203741 TI - Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase. PMID- 4203743 TI - [The development of depression in the light of animal experiments]. PMID- 4203744 TI - Immunochemistry of tetanus toxin. The nitration of tyrosyl residues in tetanus toxin. PMID- 4203745 TI - Large-scale preparation of soluble adenovirus hexon, penton and fiber antigens in highly purified form. PMID- 4203746 TI - [Action of pesticides of different chemical structures on the gonads and embryogenesis of experimental animals]. PMID- 4203747 TI - [Precancerous conditions of the esophagus and stomach]. PMID- 4203749 TI - [Solitary neurofibroma of the sigmoid in a child]. PMID- 4203748 TI - [The so-called benign tumors of the urinary tract]. PMID- 4203750 TI - [Mega-esophagus--a precancerous condition]. PMID- 4203751 TI - [Benign bladder papillomas, prognosis and treatment. Attempt at an anatomo clinical correlation]. PMID- 4203752 TI - Equine infectious anemia: plasma clearance times of passively transferred antibody in foals. PMID- 4203753 TI - Effects of altered ventricular load on the Walton-Brodie strain gauge arch. PMID- 4203754 TI - Organ blood flow during pulsatile cardiopulmonary bypass. PMID- 4203755 TI - [Peripheral para-osteo-arthropathy in spinal cord injuries (author's transl)]. PMID- 4203756 TI - [Methods of Listeria monocytogenes isolation]. PMID- 4203757 TI - [Properties of the extracellular acid proteinase of Aspergillus fumaricus mutant 128-2]. PMID- 4203758 TI - [The effect on elastin and various properties of the proteolytic enzymes of Actinomyces fradiae 119]. PMID- 4203759 TI - [Aflatoxin accumulation and lipid complex alteration in wheat and rye grain infected with Aspergillus flavus V 3734-10]. PMID- 4203760 TI - [Clinico-mycological examination for aspergillosis of patients with different pulmonary pathology]. PMID- 4203761 TI - [Clinical aspects and pathohistology of the osteoarticular tuberculosis caused by Mycobacteria of the human, bovine and avian type]. PMID- 4203762 TI - [Nonspecific infection in tuberculosis of the urinary system]. PMID- 4203763 TI - [Certain bacteriological problems of urogenital tuberculosis]. PMID- 4203764 TI - [Qualitative characteristics of the Soviet-made BCG vaccine]. PMID- 4203765 TI - [Bacteriological investigation of the caseous intrathoracic lymph nodes]. PMID- 4203766 TI - Glomerular filtration rate and extracellular fluid volumes during normoglycemia and moderate hyperglycemia in diabetics. PMID- 4203767 TI - Chimerism following fetal transfusion. Report of leucocyte hybridization and infant with acute lymphocytic leukaemia. PMID- 4203769 TI - Specificity of lymphocytotoxic anti-human antibodies in normal rabbit sera. PMID- 4203768 TI - Ferredoxins in the evolution of photosynthetic systems from anaerobic bacteria to higher plants. PMID- 4203770 TI - Further evidence for HL-A antigens present on adult peripheral red blood cells. PMID- 4203772 TI - [Problems of mutagenesis in man]. PMID- 4203771 TI - Anomalous reactivity of certain HL-A typing sera with leukemic lymphocytes. PMID- 4203773 TI - [Clinical genetic parallels in the study of congenital systemic bone diseases]. PMID- 4203774 TI - [Hereditary diseases connected with defective metabolism of polysaccharides and mixed carbohydrate-containing biopolymers]. PMID- 4203775 TI - Frequency spectrum of optokinetic nystagmus in the normal monkey. PMID- 4203776 TI - [Determination of the Zn-supply-rate using chelating agents. 1. Effect of parenteral Ca-Na-2-EDTA doses on various criteria of Zn metabolism]. PMID- 4203777 TI - Ecological significance of endosymbiosis: an overall concept. PMID- 4203778 TI - [Theory of the target: a Markovian model for the genetic evolution of a latent mutation]. PMID- 4203779 TI - Inhibition of muscle acetoacetate utilization during diabetic ketoacidosis. PMID- 4203781 TI - Elimination of free and protein-bound ionic mercury (20Hg2+) in man. PMID- 4203780 TI - Divalent cations and the release reaction of pig platelets. PMID- 4203782 TI - Inhibition of Neisseria gonorrhoeae by a factor produced by Candida albicans. AB - When Candida albicans is present on Transgrow specimens, Neisseria gonorrhoeae is detected less frequently or else can be seen in Gram stains but cannot be readily cultured. When C. albicans and N. gonorrhoeae are grown together on Transgrow, the gonococcal cells die off much more readily than N. gonorrhoeae grown on Transgrow alone. By use of a cross-streaking technique on agar plates, it has been demonstrated that C. albicans produces a soluble substance inhibitory to N. gonorrhoeae, although not to other microorganisms tested. Preliminary results indicate that this inhibitory factor can be extracted by the use of tertiary butanol. Since approximately one-third of the Transgrow specimens with growth contains yeasts, of which C. albicans is by far the most frequent, this factor presents an important complication in the diagnosis of gonorrhea in women. PMID- 4203783 TI - Lysogenic strains of group N lactic streptococci. AB - A temperate bacteriophage, designated r(1)t, was inducible from the group N lactic streptococcus, Streptococcus cremoris R(1), by ultraviolet irradiation or mitomycin C treatment. Induced lysates produced plaques on lawns of three closely related S. cremoris strains, AM(1), SK(11), and US(3). Strain SK(11) was readily lysogenized. S. cremoris AM(1) was the most reliable indicator strain, although the age of the culture used for seeding plates was critical. Zones of lysis but no plaque formation were observed on lawns of nine additional S. cremoris strains. Phage r(1)t could not be detected in filtrates of stationary-phase R(1) cultures and was near the limits of detection in logarithmically growing cultures. Phage levels were still very low (1 plaque-forming unit on AM(1) per 10 induced cells) in induced lysates of R(1) cultures. These low levels of detectable phage may be attributable to an inadequate indicator, lysogenization of the indicator, adsorption of induced phage to cellular debris, concurrent induction of other undetectable phages, or the production of high proportions of defective phages. Electron micrographs of induced R(1) lysates revealed a high incidence of incomplete phage particles, fragments, and ghosts. PMID- 4203785 TI - Pyocin sensitivity of Pseudomonas species. AB - Only the fluorescent pseudomonads, Pseudomonas aeruginosa, P. putida, and P. fluorescens, were sensitive to pyocins produced from P. aeruginosa. PMID- 4203784 TI - Morphological observations of Diplodia maydis on synthetic and natural substrates as revealed by scanning electron microscopy. AB - Mycelial and spore morphology of Diplodia maydis were investigated by using scanning electron microscopy after growth on various media and natural substrates (oat and corn kernels, and corn husks). Of several specimen preparation methods studied, Parducz fixation followed by critical-point or freeze-drying gave adequate preservation for pycnidia, mycelia, and spores. Morphological characteristics were similar in rotary and reciprocal shaker cultures and differed from that found in stationary cultures in the amount of slime-like material produced and precipitated matter on the mycelial surfaces. In general, mycelial surfaces were smooth. Large areas of coalesced material were present in all samples examined. Slime-like material produced in liquid media appeared as a finely laced net, randomly appearing throughout the mycelia with bead-like structures present along the net. A fine netting also was observed interspersed among the spores inside the pycnidia obtained from oats. Slime-like material was observed to cover the pycnidia produced on oat and corn kernels. In the latter case, the spores were less protected by the outer slime-like covering. Thickened node-like structures were observed in mycelial mats produced in modified Fries 2 medium, on potato dextrose agar plates, and on infected oats. Round and ovate thickened node-like structures were observed in mycelium produced on corn kernels. In general, node-like structures were less abundant in mycelia from naturally infected substrates. Conidia were commonly rounded to tapered and two celled, with a distinctive ridged septum at the middle. Dried spores were collapsed in a characteristic flask-like fashion. PMID- 4203787 TI - Comparison of methods for enumerating fluorescent bacteria. AB - Comparable numbers of fluorescent bacteria may be obtained by either the most probable-number procedure or by preparing spread plates on modified Henrici agar. PMID- 4203786 TI - Simplified method for the purification of group A streptococcal M-proteins: solution of the multiple banding problem. AB - A simple and rapid procedure for the isolation in high yield (about a 30% recovery based on the total 30 to 60% ammonium sulfate recovery) of homogeneous purified group A streptococcal M-protein is described. M-proteins extracted from whole cells of group A streptococci by treatment with hot HCl were neutralized, fractionated with ammonium sulfate, dialyzed, lyophilized, and then subjected to treatment with hot 60% trichloroacetic acid. This was shown to produce an M protein preparation, free of group A carbohydrate activity and extraneous antigens, in yields up to 10-fold higher than previous methods in about one-fifth the time. These M-protein preparations were shown to: (i) have similar amino acid compositions to their respective type-specific proteins purified by diethylaminoethyl and O-(carboxymethyl) cellulose chromatography, (ii) react with their respective type-specific antisera in Ouchterlony diffusion, (iii) produce antisera in rabbits capable of promoting streptococcal long-chain formation in vitro, and (iv) give only one major band on polyacrylamide gel disk electrophoresis. The data allow for an explanation of the hitherto described multiple banding M-proteins seen on acrylamide electrophoresis. PMID- 4203788 TI - Bacterial culture longevity: control by inorganic phosphate and temperature. AB - Death of cells in cultures of six species of gram-negative bacteria was accelerated by incorporation in the medium of 10-fold more inorganic phosphate than was needed for growth. Death induced by inorganic phosphate was independent of the carbohydrate employed and was enhanced by warm temperatures. PMID- 4203789 TI - Medium containing trypan blue and antibiotics for the detection of Cryptococcus neoformans in clinical samples. AB - A medium containing trypan blue, gentamicin, and chloramphenicol is introduced for the detection of Cryptococcus neoformans and Cryptococcus species from clinical samples. Ten recently isolated strains of Cryptococcus species as well as several clinical isolates of C. neoformans incorporated trypan blue and produced dark blue colonies on this mycological medium, whereas other common yeasts were light blue. The laboratory diagnosis of two cases of cryptococcosis was accomplished by the isolation of C. neoformans on the antibiotic-dye containing medium. Compared to conventional media supporting large numbers of Pseudomonas aeruginosa and other gram-negative bacilli, the new medium was selective for yeasts. In one instance, the colonization of the respiratory tract by C. neoformans which led to fungemia was traced by the use of the antibiotic dye medium. The antibiotic mixture, utilized herein, was more effective in suppressing bacteria contained in samples from patients than a medium containing cycloheximide and chloramphenicol. PMID- 4203790 TI - Method for performing aerobic plate counts of anhydrous cosmetics utilizing Tween 60 and Arlacel 80 as dispersing agents. AB - An aqueous diluent containing Tween 60 and Arlacel 80 gave greater recovery of microorganisms when compared with two common diluents as determined by aerobic plate count of inoculated anhydrous cosmetics. The greater recovery was caused by better dispersion of the anhydrous cosmetics in the diluents. PMID- 4203791 TI - Eustachian tube function in the rhesus monkey. PMID- 4203792 TI - Progressive necrotizing otitis. Malignant external otitis. PMID- 4203793 TI - Gene modulation in Drosophila: dosage compensation of Pgd+ and Zw+ genes. PMID- 4203794 TI - A ribonucleoprotein group with species- and tissue-specific biological activity. II. Tissue-specific action on the transcription and immunological properties of the RNP group. PMID- 4203795 TI - Pharmacology of the inhibition of platelet aggregation. PMID- 4203796 TI - [A comparison of intravenous tolbutamide and insulin administration during and after operation in patients with maturity-onset diabetes (author's transl)]. PMID- 4203797 TI - Heterogeneity in combining site specificity of anti-hapten antibodies produced in response to a panosyl-azoprotein conjugate. PMID- 4203798 TI - [Idiotypes of rabbit anti-Salmonella abortus-equi antibodies (recent results)]. PMID- 4203799 TI - [Comparison of idiotypes of rabbit antibodies against Salmonella abortusequi and tobacco mosaic virus. Study of cross reactions between antibody idiotypes against these 2 antigenic materials]. PMID- 4203800 TI - [Studies on N-isopropylnoradrenaline stability in aqueous solutions]. PMID- 4203801 TI - Selection for asymmetrical bias in a behavioural character of Drosophila melanogaster. PMID- 4203802 TI - Genetical variation for enzyme activity in a population of Drosophila melanogaster. I. Extent of the variation for alcohol dehydrogenase activity. PMID- 4203804 TI - Dynamics of a relationship: rhesus mother-infant ventro-ventral contact. PMID- 4203805 TI - An experimental continuous-culture unit for the production of frozen concentrated cheese starters. PMID- 4203803 TI - Bladder hyperthermia in the treatment of vesical papillomatosis. PMID- 4203806 TI - Some properties of frozen concentrated starters produced by continuous culture. PMID- 4203807 TI - In vitro generation of erythropoietic activity by the lysosome-rich fraction of rat kidneys. PMID- 4203808 TI - Experimental pyelonephritis in primates. PMID- 4203810 TI - Isolation of an acid-soluble basic protein from monkey brain. PMID- 4203811 TI - Ceramic-coated subperiosteal implants. I. A pilot study. PMID- 4203809 TI - Regional and subcellular distribution of choline acetyltransferase in the brain of rats. PMID- 4203812 TI - Editorial: Data from hospital records. PMID- 4203813 TI - Laboratory trials on oxamniquine (UK-4271), a candidate schistosomicide. PMID- 4203814 TI - Editorial: New test for Gilbert syndrome. PMID- 4203815 TI - Letter: Risk with arterial flow probes. PMID- 4203816 TI - [Proceedings: Mycotoxin symposium, 28 September 1972, in Karlsruhe. 11]. PMID- 4203818 TI - Astrocytic hamartoma of the optic disc in localized ocular neurofibromatosis (von Recklinghausen's disease). PMID- 4203817 TI - Proceedings: Spectral sensitivity of the cones measured by means of electroretinography. PMID- 4203819 TI - Absence of circulating interferon in patients with malaria and with American trypanosomiasis. PMID- 4203820 TI - Serum IgG aggregates in systemic lupus erythematosus. PMID- 4203821 TI - Effects of microbial flora on levels of colonay stimulating factor in serums of irradiated CFW mice. PMID- 4203822 TI - The use of 14C-cyanate as a method for determining erythrocyte survival. PMID- 4203823 TI - Response of rabbit testicular capsular contractions to testosterone, prostaglandin E1, and isoproterenol in vitro and in vivo. PMID- 4203824 TI - Spleen and liver responses of protein-depleted rats to dietary egg protein. PMID- 4203825 TI - Intramural diverticulosis of the oesophagus. PMID- 4203826 TI - Studies on the enzyme inducing effect of polychlorinated biphenyls. PMID- 4203827 TI - Application of sequential analysis to Evans blue-carrageenan-induced pleural effusion for screening compounds for anti-inflammatory activity. PMID- 4203828 TI - Comparative effect of carbaryl on rat reproduction and guinea pig teratology when fed either in the diet or by stomach intubation. PMID- 4203829 TI - [Antibiotic residues in poultry products]. PMID- 4203830 TI - [Diffusion precipitation reaction in Marek's disease]. PMID- 4203831 TI - [Effect of yeast on Listeria in silage]. PMID- 4203832 TI - [Effect of chronic intoxication with carbamine pesticides on the immunobiological reactivity and anti-infectious resistance]. PMID- 4203833 TI - Comparative studies on Pseudomonas aeruginosa endotoxin. PMID- 4203834 TI - [Oxygen consumption in Mycobacterium tuberculosis strains and its relation to isoniazid resistance and virulence]. PMID- 4203835 TI - Weill-Marchesani syndrome. Growth hormone, thyroid and chromosome studies. PMID- 4203836 TI - [40 percent invert sugar solution for parenteral feeding]. PMID- 4203837 TI - [Methods for analysis of amniotic fluid for diagnosis of the fetal condition in Rh-incompatibility]. PMID- 4203838 TI - [The RH-conflict and its position in present-day obstetrics]. PMID- 4203839 TI - [Chemical determination of bilirubin in the amniotic fluid in rhesus-induced morbus hemolyticus]. PMID- 4203841 TI - [Antimalarials in the treatment of porphyria cutanea tarda]. PMID- 4203840 TI - Mitochondrial nucleic acids. PMID- 4203842 TI - Treatment of acute myelogenous leukemia with 6-MPR. PMID- 4203843 TI - Effects of synthetic salmon calcitonin in osteogenesis imperfecta. PMID- 4203844 TI - Epicillin in the treatment of pharyngitis and otitis media. PMID- 4203845 TI - Topical treatment with clotrimazole in dermatomycosis. PMID- 4203847 TI - Diethylpropion hydrochloride: an effective appetite suppressant. PMID- 4203846 TI - Loperamide: an open multicentre trial and double-blind cross-over comparison with placebo in patients with chronic diarrhoea. PMID- 4203848 TI - Evaluation of EEG and clinical changes associated with pavabid therapy in chronic brain syndrome. PMID- 4203849 TI - A trial of Gerovital H-3 in depression during senility. PMID- 4203850 TI - Prediction of neuroleptic effects of CI-686 based on quantitative pharmaco electroencephalography: drug profiles and dose response curves based on computerized cerebral bio-potentials. PMID- 4203851 TI - Afrodex vs. placebo in the treatment of male impotence: statistical analysis of two double-blind crossover studies. PMID- 4203852 TI - [Postoperative fluid therapy]. PMID- 4203855 TI - Musical wind instrumentalists: facial pain and tooth movement. PMID- 4203854 TI - The structure of dental practice in Connecticut: a summary from the 1971 practice survey. PMID- 4203853 TI - The repair of fractured anterior teeth using an etch technic sealant, and a composite restorative material. PMID- 4203856 TI - Yolk proteins in Drosophila: identification and site of synthesis. PMID- 4203857 TI - [Theory of adult nursing]. PMID- 4203859 TI - [Assistance and encouragement of patients with chronic diseases and extended hospitalization]. PMID- 4203858 TI - [Postoperative physical training at the bedside]. PMID- 4203860 TI - [Nursing of aged terminal patients with strong tendencies twoard psychophysiologic disorders]. PMID- 4203861 TI - [Approach in nursing of patients with muscular dystrophy. A case of m muscular dystrophy in a young adult]. PMID- 4203863 TI - [A case conference at the Osaka Municipal Adult Disease Center. An aged patient scheduled for surgery of esophageal cancer]. PMID- 4203862 TI - [Schizophrenic patients without self confidence after a prolonged hospitalization: assistance in their effort toward social rehabilitation]. PMID- 4203864 TI - [The problem-oriented system for patient-centered care]. PMID- 4203865 TI - [Nursing technology for the greater comfort of the patient]. PMID- 4203866 TI - [Bare-foot doctors of China]. PMID- 4203867 TI - [Changes in life expectancy]. PMID- 4203868 TI - [Characteristics of nursing of aged patients]. PMID- 4203869 TI - [Blood pressure and hypertension]. PMID- 4203870 TI - [Study of human development. 5. Characteristics and developmental problems in adolescent, adult and aged groups]. PMID- 4203871 TI - [Transfer technic. 5. Lifting of the patient from the bed]. PMID- 4203872 TI - [Theory of assistance as a starting point in nursing. 21. Re-evaluation of practical technic of assistance. (7)]. PMID- 4203873 TI - [Psychology of interpersonal relations in nursing. 12. Caution against angelism]. PMID- 4203875 TI - [Medicine and civilization. 12. Heredity and man]. PMID- 4203874 TI - [Death and nursing. 12. Possibility of psychological counseling in dying patients: acceptance of death by patients]. PMID- 4203876 TI - Fibrinogen derivatives with a higher molecular weight than that of the parent molecule in cord vein plasma of newborns. I. Identification in single plasma samples. PMID- 4203877 TI - [Vitamin B12 binding glycoproteins. VIIth. Unsaturated 57Co-cyanocobalamin binding capacity of glycoproteins in chronic myelogenous leukaemia (author's transl)]. PMID- 4203878 TI - [Dysgammaglobulinaemia type I (author's transl)]. PMID- 4203879 TI - [Editorial: What is intravenous hyperalimentation?]. PMID- 4203880 TI - [The radiosensitivity of different conformations of native DNA in solution]. PMID- 4203881 TI - [Chemical protection of transforming DNA]. PMID- 4203882 TI - [Phenomonologic features of photomodification of radiation injuries in the blue green alga Plectonema boryanum]. PMID- 4203883 TI - [Extracardial effects of vasoactive drugs on the entire circulation of the dog (author's transl)]. PMID- 4203885 TI - The ultrastructure of striated muscle in malformed chick limb induced by citral. PMID- 4203884 TI - Spontaneous perforation of intrathoracic colon following total esophagectomy. PMID- 4203886 TI - [Histomorphology of the experimental necrosis of fat tissue (author's transl)]. PMID- 4203887 TI - [On the fine structure of gall bladder and biliary ducts. IV. The cholesterosis of the human gall bladder mucosa (author's transl)]. PMID- 4203888 TI - [Capacity of regeneration in liver epithelia of juvenile, repeated partially hepatectomized rats. Autoradiographic studies after continous infusion of 3H thymidine (author's transl)]. PMID- 4203889 TI - Fetal hemopoiesis. I. Electron microscopic studies on human yolk sac hemopoiesis. PMID- 4203890 TI - [The influence of sex, pregnancy and age of the incidence of the HIPA plasmocytoma of the BALB-c-mice after cellfree tumor transmission (author's transl)]. PMID- 4203891 TI - Fine structural changes of allergic aspermatogenesis in the guinea pig. I. The similarity in the initial changes induced by passive transfer of anti-testis serum and by immunization with testicular tissue. PMID- 4203892 TI - Fine structural changes of allergic aspermatogenesis in the guinea pig. II. Induced by the homologous parotid gland as antigen. PMID- 4203893 TI - Nephritogenic properties of nephrotoxic guinea pig antibodies. I. Glomerulonephritis induced by guinea pig IgG antibody in rats. PMID- 4203894 TI - [Various problems of memory and the role of the limbic system in the registration of information]. PMID- 4203895 TI - [Participation of the cholinoreactive portion of the brain in conditioned reflex activity]. PMID- 4203897 TI - The corpus luteum of the rhesus monkey (Macaca mulatta) during late pregnancy. An electron microscopic study. PMID- 4203896 TI - Quantitative studies on the drainage of the cerebrospinal fluid into the lymphatic system. PMID- 4203899 TI - Indomethacin block of normal onset of parturition in primates. PMID- 4203898 TI - In vitro metabolism of palmitic acid and glucose in the developing tissue of the rhesus monkey. PMID- 4203900 TI - Recent developments in radiotherapy. PMID- 4203901 TI - The influence of 1-nitro-9(3'-dimethylamino-propylamino)-acridine on biosynthesis of DNA, RNA and protein in synchronized cultures of Euglena Gracilis. PMID- 4203902 TI - Zinc, an essential metal ion for beef liver delta-aminolevulinate dehydratase. PMID- 4203903 TI - Transformation of Bacillus subtilis using gently lysed L-forms; a new mapping technique. PMID- 4203904 TI - Identity of the HL-A common portion fragment and human beta2-microglobulin. PMID- 4203906 TI - Enhancement of the biological activities of soybean agglutinin by cross-linking with glutaraldehyde. PMID- 4203905 TI - Characterization of a disulfide bridge linking the J chain to the alpha chain of polymeric immunoglobulin A. PMID- 4203907 TI - Purification and properties of the hemagglutinin from Sophora japonica seeds. PMID- 4203908 TI - On the structure of ovotransferrin. I. Isolation and characterization of cyanogen bromide fragments. Reevaluation of the primary structure. PMID- 4203909 TI - 3-Phosphoglycerate kinase from rat tissues. Further characterization and developmental studies. PMID- 4203911 TI - Macroglobulinemia in a child with acute leukemia. PMID- 4203910 TI - Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. PMID- 4203912 TI - Effects of anticoagulants and storage on granulocyte function in bank blood. PMID- 4203913 TI - Effect of phenobarbitone on bile flow and bilirubin metabolism in man and the rat. PMID- 4203915 TI - Sherrington was right about the trapezius muscle innervation. PMID- 4203914 TI - [Effect of some synthetic materials (plastmass) on the bone marrow of rabbits]. PMID- 4203916 TI - Antihypertensive and central nervous system depressant properties of 3-(gamma-p fluorobenzoyl propyl) 2,3,4,4a,5,6-hexahydro-1(H)-pyrazino(1,2-a) quinoline hydrochloride (compound 69-183, centpyraquin). PMID- 4203917 TI - Studies on phytohemagglutinins XV. Hemagglutinins of the pea and the lentil: advantage of their application in comparison to concanavalin A in some agglutination reactions. PMID- 4203918 TI - [Selective substrate for the isolation of Listeria monocytogenes]. PMID- 4203919 TI - Thin layer chromatography methods for detecting hippurate hydrolase activity among various bacteria (Pseudomonas, Bacillus, Enterobacteriaceae). PMID- 4203920 TI - Emergence of bacteria resistant to gentamicin. PMID- 4203921 TI - The efficacy of animal studies in predicting clinical toxicity of cancer chemotherapeutic drugs. PMID- 4203922 TI - Fate of the T1 strain of Mycoplasma mycoides in cattle following vaccination. PMID- 4203923 TI - Susceptibility of mammalian and avian cell cultures to infection with cell-free turkey herpes virus. PMID- 4203924 TI - The influence of pH and histidine dipeptides on the production of staphylococcal alpha-toxin. PMID- 4203926 TI - Microbiological assay for purine analogues with Lactobacillus casei. PMID- 4203925 TI - Formation and properties of protoplasts from antibiotic-producing strains of Penicillium chrysogenum and Cephalosporium acremonium. PMID- 4203928 TI - The co-existence of acoustic neuroma and otosclerosis. PMID- 4203927 TI - Localization of a primate-specific esterase using immunofluorescence and immunoperoxidase techniques. PMID- 4203929 TI - Comparative immunological and electrophoretic studies on ribosomal proteins of bacillaceae. PMID- 4203930 TI - Comparison of ribosomal RNA-binding protein "L2" isolated from different bacterial species. PMID- 4203931 TI - Erythromycin resistant mutants of Bacillus subtilis. PMID- 4203932 TI - Chloramphenicol resistant mutants of Bacillus subtilis. PMID- 4203933 TI - Platinum coordination complexes in cancer chemotherapy. PMID- 4203934 TI - [The process of production of various aromatic substances by the lactic acid microbes Ped. cerevisiae and Lact. plantarum when cultured together for the purpose of using them in production of boiled sausage]. PMID- 4203935 TI - [Conditions for coagulation of the biomass of a culture of Bacillus subtilis 103]. PMID- 4203936 TI - [Growth of hydrogen bacteria on urine as a source of nitrogen]. PMID- 4203937 TI - Peripelvic new bone formation in hemophilia. Report of three cases. PMID- 4203938 TI - The effects of airway occlusion after oxygen breathing on the lungs of newborn infants. Radiologic demonstration in the experimental animal. PMID- 4203939 TI - Weekly total-skin electron-beam irradiation for mycosis fungoides. PMID- 4203940 TI - Comparative beam data for the 25 MV betatron, 8, 6, and 4 MV linear accelerators, and 60Co units. Central-axis depth dose, field flatness, and decrement lines. PMID- 4203941 TI - A new 10 MeV linear accelerator for radiation therapy. PMID- 4203942 TI - The use of ketamine anesthesia in radiation therapy. PMID- 4203943 TI - Tomography applied to knee arthrography. PMID- 4203944 TI - Proton radiation therapy. PMID- 4203945 TI - Normal and neoplastic tissue effects of high intensity intracavitary irradiation: cancer of the corpus uteri. PMID- 4203946 TI - [The function of memory and organization of behavior in simians]. PMID- 4203947 TI - The kinetics of extracellular protease production in an abnormal sporulation mutant of B. subtilis. PMID- 4203948 TI - Quantitative studies on the dissociation equilibrium of HeLa cell ribosomes. PMID- 4203949 TI - Scanning electron microscopic observation of the organ of Corti of the rhesus monkey. PMID- 4203951 TI - Mammalian-lung galactan. PMID- 4203950 TI - Asymptomatic gonorrhea in the male. AB - In a prospective study, 133 male contacts of 102 women with gonorrhea were examined. A diagnosis of gonorrhea was made in 63 patients, indicating an infection rate of 47% after exposure. Forty-three percent of the patients with gonorrhea were asymptomatic. The duration of the asymptomatic period ranged from 3 to 154 days. The epidemiologic importance of this hidden infectious reservoir is stressed. PMID- 4203952 TI - The long-term maintenance treatment of schizophrenic out-patients with depot flupenthixol. PMID- 4203953 TI - [Collective review: drug resistance of coccidia oocysts]. PMID- 4203954 TI - Human alpha1-antitrypsin. PMID- 4203955 TI - Comparison of 115m cadmium retention in rats following different routes of administration. PMID- 4203956 TI - Glomerular ultrafiltration. PMID- 4203957 TI - Prostaglandins, calcium metabolism and cancer. PMID- 4203958 TI - Competition of the thyroid hormones for binding sites on rat adenohypophyseal proteins in vitro. PMID- 4203959 TI - Pattern formation in the blue-green alga Anabaena. II. Controlled proheterocyst regression. PMID- 4203960 TI - Cyclic membrane flow in the ingestive-digestive system of peritrich protozoans. I. Vesicular fusion at the cytopharynx. PMID- 4203961 TI - Cyclic membrane flow in the ingestive-digestive system of peritrich protozoans. II. Cup-shaped coated vesicles. PMID- 4203962 TI - Further observations on the fine structure of freeze-cleaved tight junctions. PMID- 4203963 TI - Ultrastructural changes in Euglena after ultraviolet irradiation. PMID- 4203964 TI - Do lysophospholipids really exist in Tetrahymena pyriformis? PMID- 4203965 TI - [A thin-layer chromatographic screening test for the detection of inhibiting properties of phenylurea herbicides on certain enzymes (author's transl)]. PMID- 4203966 TI - Contact B-scan ultrasound. PMID- 4203967 TI - Mediastinal ultrasonography. PMID- 4203968 TI - Ankle blood pressures in vascular insufficiency involving the legs. PMID- 4203970 TI - 70mm camera for ultrasound B-scanning. PMID- 4203969 TI - Echocardiographic demonstration of bacterial vegetations in active infective endocarditis. PMID- 4203971 TI - Radiolucent intraocular foreign body localization: a case study. PMID- 4203972 TI - Digital computer analysis of time-amplitude ultrasonograms from the human eye. I. Signal acquisition. PMID- 4203973 TI - Digital computer analysis of time-amplitude ultrasonograms from the human eye. II. Data processing. PMID- 4203975 TI - Left atrial mass simulating cardiomyopathy. PMID- 4203974 TI - Ultrasonic diagnostic procedures in obstetrics and gynecology. PMID- 4203976 TI - Echographic aortic valve oriface dimension: its use in evaluating aortic stneosis and cardiac output. PMID- 4203977 TI - Gray scale ultrasound. PMID- 4203978 TI - Real-time cross-sectional ultrasonic imaging of the heart using a linear array multi-element transducer. PMID- 4203979 TI - Training tank: a method for training technicians in ultrasound scanning. PMID- 4203980 TI - A sealed test tank for echoscope performance evaluation. PMID- 4203981 TI - Ultrasound in the diagnosis of liver disease. PMID- 4203984 TI - Sarcocystis in the northern fur seal. PMID- 4203982 TI - Comparison of frog albumins with those of other vertebrates. PMID- 4203985 TI - [15 cases of stomach diverticula]. PMID- 4203983 TI - Effect of cations on the blood platelet release reaction. AB - 1. Stimulus-secretion phenomena in blood platelets incubated with trypsin or thrombin have been investigated.2. Secretion occurs in at least two stages: (a) induction, obtained when the platelets are incubated with proteolytic enzymes in the presence of the chelating agent EDTA, and (b) release, which occurs with the subsequent addition of Ca(2+) to the incubation medium.3. Ca(2+) was the only essential divalent cation required for release. Ba(2+) and Mg(2+) inhibited release and Sr(2+) could only partially substitute for Ca(2+).4. Blood platelets exhibited recovery from enzymic perturbation by trypsin or thrombin by a mechanism that was temperature dependent, but did not require the synthesis of new protein.5. The results are discussed in relationship to stimulus-secretion in other cells. PMID- 4203986 TI - [On the sensitivity to TUM-N of tubercle bacilli isolated from tuberculous patients who had never employed TUM-N--for determination of the critical concentration of TUM-N resistance (author's transl)]. PMID- 4203987 TI - [Electrophoretic mobility of 19 S-IgM in discontinuous acrylamid columns (author's transl)]. PMID- 4203988 TI - Variation with sex of irradiation-induced chromosome damage in somatic cells of Drosophila melanogaster. PMID- 4203989 TI - Measurement of human placental lactogen with a simple immunodiffusion kit (Plac- Gest). PMID- 4203990 TI - [Cervical esophagotomy performed for feeding purposes following laryngectomy]. PMID- 4203991 TI - Changes of 17-hydroxycorticosteroids and growth hormone during self-stimulation in monkeys. PMID- 4203992 TI - A torque device for studies of primate limb movements. PMID- 4203993 TI - Effects of protein-calorie deficiencies on the learning ability of the Wistar rat. PMID- 4203994 TI - Emergency management of the patient with seizures. 1. Classification and treatment system, common seizure disorders. PMID- 4203995 TI - Blood metabolites in the diagnosis and treatment of diabetes mellitus. PMID- 4203996 TI - [Effect of rifampicin and ethambutol on Mycobacterium tuberculosis in vitro]. PMID- 4203997 TI - [Incidence of detection of Mycobacterium tuberculosis in resected lungs of patients with restricted forms of pulmonary tuberculosis]. PMID- 4203998 TI - [Effect of certain conditions on the development of streptomycin-resistant forms of M. tuberculosis]. PMID- 4203999 TI - [Comparative evaluation of different methods in determining the virulence of Mycobacterium tuberculosis]. PMID- 4204000 TI - Parathyroid hormone effects in rats treated with diphosphonate. AB - The ability of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP; 40 milligrams per kilogram of body weight per day) to reduce the hypercalcemic effect of parathyroid hormone in thyroparathyroidectomized rats was confirmed. However, treatment with this large dose of EHDP enhanced the hypophosphatemic effect of a low dose of parathyroid hormone (10 international units per100 grams of body weight), apparently by promoting the renal excretion of phosphate. The data suggest that EHDP may have a direct effect on the renal action of parathyroid hormone and, in this way, may also affect vitamin D metabolism by the kidney. PMID- 4204001 TI - [TRH stimulation test. II. Evaluation of thyroid response]. PMID- 4204002 TI - [TRH stimulation test. II. Evaluation of thyroid response]. PMID- 4204003 TI - [Shock]. PMID- 4204004 TI - [Toxoplasma gondii, Isospora felis-natural and experimental infection in cats]. PMID- 4204005 TI - [Muskrat--a natural carrier of Toxoplasma]. PMID- 4204006 TI - [Antibodies and strains of the Toxoplasma in guinea-pigs (Cavia porcellus L.)]. PMID- 4204007 TI - [Toxoplasma gondii Nicole et Manceaux 1909-antibodies in domestic rabbits]. PMID- 4204008 TI - The incidence of the various biotypes of Brucella abortus in cattle in the south west of Scotland. PMID- 4204009 TI - Bovine farmers' lung: a clinical syndrome in a herd of cattle. PMID- 4204010 TI - Continuing education for physicians: report of a WHO Expert Committee. PMID- 4204011 TI - [Thio-tepa in the prevention of recurrences of papillary bladder tumors]. PMID- 4204012 TI - On the impulse conducting system of the monkey heart (Macaca mulatta). II. The atrio-ventricular node and bundle. PMID- 4204013 TI - [Evoked potentials in the caudate nucleus of the monkey Macaca rhesus in response to stimulation of different areas of the ipsilateral cerebral cortex]. PMID- 4204014 TI - Immunoglobulins in populations of subtropical and tropical countries. PMID- 4204015 TI - Critique of the assay and significance of bilirubin conjugation. PMID- 4204016 TI - Skin manifestations of meningococcal infection; an immediate indicator of prognosis. PMID- 4204017 TI - Autoimmune hemolytic anemia in a 6-week-old infant. PMID- 4204018 TI - An unusual case of childhood chloral hydrate poisoning. PMID- 4204019 TI - Treatment of glottic carcinoma by megavoltage radiation therapy and results. PMID- 4204020 TI - Matrix dosemeter to study the uniformity of high energy x-ray beams. PMID- 4204021 TI - Zoonotic potential (Rocky Mountain spotted fever aed tularemia) in the Tennessee Valley region. II. Prevalence of Rickettsia rickettsi and Francisella tularensis in mammals and ticks from Land Between the Lakes. PMID- 4204022 TI - Studies on the sequential immunization against group B arboviruses in squirrel monkeys, cynomolgus monkeys, rhesus monkeys, and chimpanzees. PMID- 4204023 TI - Experimental infections with African Trypanosomes. VI. Glomerulonephritis involving the alternate pathway of complement activation. PMID- 4204024 TI - Response to treatment in man of multi-drug resistant Plasmodium falciparum from Panama. PMID- 4204026 TI - Schistosoma japonicum infection in monkeys and baboons: parasitological and pathological findings. PMID- 4204025 TI - Immunodiagnosis of human trichinosis using counterelectrophoresis and agar gel diffusion techniques. PMID- 4204027 TI - Comparative efficacy of one and two treatments with tubercidin against Schistosomiasis japonica in monkeys. PMID- 4204028 TI - Schistosomiasis mansoni in baboons. II. Acquisition of immunity to challenge infection after repeated small exposures to cercariae of Schistosoma mansoni. PMID- 4204029 TI - Dermal sensitivity to paracoccidiodin and histoplasmin in family members of patients with paracoccidioidomycosis. PMID- 4204030 TI - Zoonotic potential (Rocky Mountain spotted fever and tularemia) in the Tennessee Valley region. I. Ecologic studies of ticks infesting mammals in Land Between the Lakes. PMID- 4204031 TI - Effects of diffuse transcerebral electrical currents on cortical unit potential activity. PMID- 4204032 TI - Gold salts in the treatment of rheumatoid arthritis. A double-blind study. PMID- 4204033 TI - Serum hyperviscosity in Sjogren's syndrome interaction between IgG and IgG rheumatoid factor. PMID- 4204035 TI - Some factors influencing the chemical composition of mixed rumen bacteria. PMID- 4204034 TI - The fusion of erythrocytes by fatty acids, esters, retinol and alpha-tocopherol. AB - 1. The ability of a number of carboxylic acids, their esters, retinol and alpha tocopherol to induce fusion of hen erythrocytes in vitro was investigated. 2. Some 30 different fat-soluble substances (100mug/ml) were found to cause the formation of multinucleated erythrocytes with a suspension of 3x10(8) erythrocytes/ml. The most effective agents induced fusion within 5-10min at 37 degrees C; some substances required about 1h. 3. Inclusion of Dextran 60C in the test medium minimized colloid osmotic lysis caused by exogenous lipids that induce cell fusion. 4. Cell swelling, followed by cell adhesion, was then seen to precede cell fusion. 5. Fusion occurred with C(10)-C(14) saturated carboxylic acids, with unsaturated, longer-chain carboxylic acids and their mono-esters; retinol, and to a lesser extent alpha-tocopherol, also caused cell fusion. 6. C(6)-C(9), C(15), C(16) and C(18) saturated carboxylic acids did not induce fusion within 4h; glyceryl dioleate was only weakly active, and glyceryl trioleate was inactive in the test system. 7. Fusion was facilitated by a high ratio of chemical agents to cell number and by incubation between pH5 and 6. It was inhibited by EDTA and by serum albumin. 8. Glyceryl mono-oleate caused both a similar fusion of several species of mammalian erythrocyte and the interspecific fusion of human and chicken erythrocytes. 9. The term ;fusogenic' is proposed to describe chemical, viral and physical agents that cause membranes to fuse. 10. The biochemical mechanisms involved and the possible biological significance of membrane fusion by fusogenic lipids are discussed. PMID- 4204036 TI - [Transport of tritiated oleic acid through the enterocyte, in rats, studied with radioautography in electron microscopy]. PMID- 4204037 TI - [Regeneration of the pharynx in the planarium Dugesia tigrina]. PMID- 4204038 TI - [Effects of vinblastine on the morphogenesis of the chick embryo foot]. PMID- 4204039 TI - [Complete separation of palmityl-CoA-ACP-transacylase activity and malonyl-CoA ACP-transacylase activity in homogenates of Mycobacterium smegmatis]. PMID- 4204040 TI - [Isolation and structural study of 16 oligosaccharides isolated from human urine]. PMID- 4204041 TI - [Proposed criterion for the classification of yeasts: enzymatic hydrolysis of the cell wall]. PMID- 4204043 TI - [Identification and estimate of the molecular weights of the ribonucleic acids of cucumber mosaic virus (VMC strain D)]. PMID- 4204042 TI - [Detergent properties of bacteriocin molecules]. PMID- 4204044 TI - [Difference in enzymatic activity among lymphoblastoid lines of various origins: cancer of the nasal pharynx (NPC), Burkitt's lymphoma (BL), infectious mononucleosis, and normal subjects]. PMID- 4204045 TI - [Reversibility of the clinical signs of cirrhosis in chronic alcoholism after abstention]. PMID- 4204046 TI - Conjugation of bromosulphthalein (BSP) with reduced glutathione in the gastrointestinal tract in vertebrate species. PMID- 4204047 TI - Abnormal proteins in Drosophila melanogaster subsequent to 5-bromodeoxyuridine administration. PMID- 4204049 TI - The effect of allatectomy on glycogen metabolism in the fat body of the female housefly, Musca domestica L. PMID- 4204050 TI - Stimulation of pituitary prolactin and TSH release in lactating and proestrous rats. PMID- 4204048 TI - Alteration of L-alanine aminotransferase, L-aspartate aminotransferase and beta hydroxyacyl dehydrogenase activities in Drosophila melanogaster larvae by nutritional manipulation. PMID- 4204051 TI - Isolation and characterization of lipoprotein-X (LP-X) from canine. PMID- 4204052 TI - Cytoplasmic site synthesis of chloroplast aminoacyl-tRNA synthetases in Euglena gracilis. PMID- 4204054 TI - Editorial: Fitting long-term care to the patient's needs. PMID- 4204053 TI - Alkaline phosphatase activity associated to a calcium binding glycoprotein from calf scapula cartilage. PMID- 4204055 TI - Diagnosis of pulmonary fungous infections. PMID- 4204057 TI - Hemolytic and conglutinating complement in normal and pathologic human sera. PMID- 4204056 TI - Distribution of 125I-prolactin in mice and rats. Studies with whole-body and microautoradiography. PMID- 4204058 TI - Wine in the treatment of long-term geriatric patients in mental institutions. PMID- 4204059 TI - Anderson-Fabry disease: a histopathological study of three cases with observations on the mechanism of production of pain. AB - A clinical review and histopathological study of three cases of Anderson-Fabry disease is presented and pathological changes in the central and peripheral nervous systems are reported, in some sites for the first time. These are telangiectatic changes in vessels of the sympathetic ganglia in the vertebral trunk; storage of glycolipid in pigmented cells of the substantia nigra and in anterior horn cells; and degeneration of nerve fibres in the dorsal root entry zone and substantia gelatinosa of the spinal cord. The histopathological findings suggest that in this disease pain is due to involvement of dorsal root ganglion cells with associated axonal degeneration of the small fibres in pathways subserving pain. PMID- 4204061 TI - [Acquired diverticuli of the duodenum and jejunum]. PMID- 4204062 TI - Neurofibromatosis with laryngeal involvement. PMID- 4204060 TI - Cerebral circulatory and metabolic effects of hypotension produced by deep halothane anaesthesia. AB - Hypotension to a mean blood pressure of 33 mmHg for periods of 70 to 187 minutes was induced by increasing the inspired halothane concentration in 11 baboons which were already anaesthetized with 0.5% halothane, nitrous oxide, and oxygen. During hypotension, cerebral blood flow, measured by Xenon clearance and by a carotid electromagnetic flowmeter, decreased by more than half, and sagittal sinus oxygen saturation was 46%. Cerebral oxygen uptake fell from 5.15 to 3.56 ml./100 g/min at this deeper level of halothane anaesthesia. Cerebral hyperaemia developed after hypotension in those animals which regained a mean blood pressure greater than 70 mmHg. Acidbase measurements on CSF from the cisterna magna revealed no metabolic acidosis during or after hypotension. In all four animals with intact autoregulation before hypotension, this was absent or impaired afterwards. PMID- 4204063 TI - Allelic contracomplementation possible mechanism for initiating sympatric speciation. PMID- 4204064 TI - Genetically based behaviour patterns in Drosophila melanogaster. PMID- 4204065 TI - Immunological reactions in scrapie: the basis of a rapid titration method. PMID- 4204066 TI - [Comparative study of the ultrastructure and excretion induced by thrombin of washed platelets prepared from blood samples conserved on EDTA and acidified ACD]. PMID- 4204068 TI - Monoamine changes in experimental head and spinal cord trauma: failure to confirm previous observations. PMID- 4204067 TI - [Dynamics of insulin secretion promoted by amino acids in essential obesity in women]. PMID- 4204069 TI - Right ovarian vein syndrome. Six-year critique. PMID- 4204070 TI - Gigantic traumatic vesical pseudodiverticulum. PMID- 4204072 TI - Editorial: Subhuman primates in biomedical research. PMID- 4204071 TI - Why the monkey? Use of nonhuman primates in urologic research. PMID- 4204073 TI - [Short review on intensive parenteral carbohydrate therapy]. PMID- 4204074 TI - [Sterilization of biologic heart valve prostheses with glutardialdehyde]. PMID- 4204075 TI - Cochlear pathology in monkeys exposed to impulse noise. PMID- 4204076 TI - The relation between temporary threshold shift and permanent threshold shift in rhesus monkeys exposed to impulse noise. PMID- 4204077 TI - Deafening effects of impulse noise on the rhesus monkey. PMID- 4204078 TI - The relationship between permanent threshold shift and the loss of hair cells in monkeys exposed to impulse noise. PMID- 4204080 TI - Comparison of arterial lesions and serum lipids in spider and rhesus monkeys on an egg and butter diet. PMID- 4204079 TI - Comparative lipid response of four primate species to dietary changes in fat and carbohydrate. PMID- 4204082 TI - Photodecomposition of chlorinated biphenyls and dibenzofurans. PMID- 4204081 TI - [Experimental studies on the actinomycetic activity of 5-chlor-8-hydroxyquinoline in the agar diffusion test]. PMID- 4204083 TI - [Treatment of painful drepanocytic crises with Hydergine]. PMID- 4204084 TI - [Waldenstrom's disease with osseous lacunae (apropos of a case in a black African]. PMID- 4204085 TI - Trimethoprim in normal and pathological human lung tissue. PMID- 4204086 TI - Relative antagonism in vitro of calcium in serum to the bactericidal activities of gentamicin and tobramycin on Pseudomonas aeruginosa. PMID- 4204087 TI - The use of oxyphenbutazone ('Tanderil') in acute pelvic inflammatory disease. PMID- 4204088 TI - Triple tetracycline ('Deteclo') as a single dose oral treatment of uncomplicated gonorrhoea in the male. PMID- 4204089 TI - Two trials comparing 'Hydergine' with placebo in the treatment of patients suffering from cerebrovascular insufficiency. PMID- 4204090 TI - A clinical trial comparing 'Hydergine' with placebo in the treatment of cerebrovascular insufficiency in elderly patients. PMID- 4204091 TI - Pharmacodynamic aspects of two sulphonylurea derivatives glipizide and glibenclamide. PMID- 4204092 TI - Unaltered glucagon secretion after seven days of sulphonylurea administration in normal subjects. PMID- 4204093 TI - An open comparative study of the efficacy and tolerance of a new antidiabetic agent: glipizide. PMID- 4204094 TI - The epidermal ball cell of toad larvae (Bufo b. bufo Linne, Bufo calamita Laurenti). PMID- 4204095 TI - Clinical aspects of cluster headache. PMID- 4204096 TI - Rabbit IgG heavy chains: evolutionary divergence of genes coding for constant region. PMID- 4204097 TI - Inactivation of trypsin by antibodies of high affinity. PMID- 4204098 TI - Demonstration of rubella IgM antibody by indirect fluorescent antibody staining, sucrose density gradient centrifugation and mercaptoethanol reduction. PMID- 4204099 TI - Effect of diluent on bacterial counts in milk and milk products. PMID- 4204100 TI - Membranes of mammary gland. 8. Isolation and composition of nuclei and nuclear membrane from bovine mammary gland. PMID- 4204101 TI - Intrahypothalamic injections of prostaglandins and prostaglandin antagonists and feeding in sheep. PMID- 4204102 TI - Maturation of the head of bacteriophage T4. I. DNA packaging events. PMID- 4204104 TI - Surface ultrastructure of the mucosa of the soft palate in the vervet monkey. PMID- 4204103 TI - Fatty acid distribution in lipids and 32P incorporation into phospholipids during early amphibian development. PMID- 4204105 TI - Baboon peripheral lymphocyte response to phytohaemagglutinin. PMID- 4204106 TI - Routine autoradiography of tissue culture monolayers. PMID- 4204107 TI - Red cell carbonic anhydrases B and C (CA B and CA C). PMID- 4204108 TI - Immunization, isolation of immunoglobulins, estimation of antibody titre. PMID- 4204109 TI - Comparison of antigens: the reaction of 'identity'. PMID- 4204110 TI - Comparison of antigens: the reaction of partial identity. PMID- 4204111 TI - Comparison of two regimens of simplified two-stage chemotherapy in previously untreated pulmonary tuberculosis. PMID- 4204112 TI - Studies on the treatment of experimental tuberculosis of the guinea pig with intermittent doses of isoniazid. PMID- 4204113 TI - Characterization of haemolytic enterococci isolated from oral infections. PMID- 4204115 TI - On-line analysis of optokinetic nystagmus by small general purpose digital computer. PMID- 4204114 TI - Susceptibility of haemolytic oral enterococci to eight antibiotics in vitro. PMID- 4204116 TI - Complex formation between macromolecules and drugs. IX. The competition between two sulfa drugs and phenobarbital, pentobarbital or phenoxymethyl penicillin for binding sites on human serum albumin. PMID- 4204118 TI - [Anesthesia and resuscitation in acute surgical peritonitis]. PMID- 4204117 TI - [Study of protein metabolism and the fate of perfused amino acids in intensive care patients in the post-aggressive period]. PMID- 4204119 TI - [Evaluation and difficulties of prolonged parenteral feeding in intestinal surgery in children. (On 4 cases in children from 7 to 14 years of age)]. PMID- 4204121 TI - Ribosomes in reticulocyte maturation. PMID- 4204120 TI - [Ectopic ossification: a complication after total hip replacement (author's transl)]. PMID- 4204122 TI - Interconvertible forms of bacterial RNA polymerase. PMID- 4204124 TI - The role of oligodendroglia and astroglia in Wallerian degeneration of the optic nerve. PMID- 4204123 TI - Visualization of genetic transcription. PMID- 4204125 TI - Immunochemical and immunofluorescence studies of the glial fibrillary acidic protein in vertebrates. PMID- 4204126 TI - A cingulo-amygdaloid projection in the rhesus monkey. PMID- 4204127 TI - Studies on the visual area MT in primates. II. Projection fibers to subcortical structures. PMID- 4204128 TI - Visual receptive fields of frontal eye field neurons. PMID- 4204129 TI - Radioautographic localization of inhibition of protein synthesis in specific regions of monkey brain. PMID- 4204130 TI - Firing changes in cells of the nucleus medialis dorsalis associated with delayed response behavior. PMID- 4204131 TI - Effects of cooling prefrontal cortex on cell firing in the nucleus medialis dorsalis. PMID- 4204132 TI - Reduction in severity and extent of myocardial infarction when nitroglycerin and methoxamine are administered during coronary occlusion. PMID- 4204133 TI - Intraoperative coronary collateral function in patients with coronary occlusive disease. Nitroglycerin responsiveness and angiographic correlations. PMID- 4204134 TI - Simultaneous measurement of total and nutritional coronary blood flow in dogs. PMID- 4204135 TI - Oral treatment in diabetes. PMID- 4204136 TI - Diabetic coma. PMID- 4204137 TI - A computer system for interactive processing and evaluation of light stimulated evoked responses. PMID- 4204138 TI - The pharmacology of lorazepam, a broad-spectrum tranquillizer. PMID- 4204139 TI - Precipitin reactions between insulin, proinsulin, insulin chains and insulin antibody. PMID- 4204140 TI - Absorption of hemoglobin and hemoglobin iron in alcohol-induced liver injury. PMID- 4204141 TI - The method of intraluminal perfusion of the human small intestine. 3. Absorption studies in disease. PMID- 4204142 TI - Epidemilogy in the undergraduate curriculum of an African medical school. PMID- 4204143 TI - Auditory delayed matching in the bottlenose dolphin. AB - A bottlenose dolphin, already highly proficient in two-choice auditory discriminations, was trained over a nine-day period on auditory delayed matching to-sample and then tested on 346 unique matching problems, as a function of the delay between the sample and test sounds. Each problem used new sounds and was from five to 10 trials long, with the same sound used as the sample for all trials of a problem. At each trial, the sample was projected underwater for 2.5 sec, followed by a delay and then by a sequence of two 2.5-sec duration test sounds. One of the test sounds matched the sample and was randomly first or second in the sequence, and randomly appeared at either a left or right speaker. Responses to the locus of the matching test sound were reinforced. Over nine, varying-sized blocks of problems, the longest delay of a set of delays in a block was progressively increased from 15 sec initially to a final value of 120 sec. There was a progressive increase across the early blocks in the percentage of correct Trial 1 responses. A ceiling-level of 100% correct responses was then attained over the final six blocks, during which there were 169 successive Trial 1 responses bracketed by two Trial 1 errors (at 24- and 120-sec delays). Performance on trials beyond the first followed a similar trend. Finally, when the sample duration was decreased to 0.2 sec or less, matching performance on Trial 1 of new problems dropped to chance levels. PMID- 4204144 TI - Phagocytosis and processing of bacteria by peritoneal macrophages. PMID- 4204145 TI - Efficacy of ribosomal preparations from Pseudomonas aeruginosa to protect against intravenous Pseudomonas challenge in mice. PMID- 4204146 TI - Efficacy of neomycin aerosols in the treatment of burns. PMID- 4204147 TI - [Treatment of diabetes with euglucon 5 in a hospital for the aged (author's transl)]. PMID- 4204148 TI - Increased aflatoxin G1 production by Aspergillus flavus via gamma irradiation. PMID- 4204149 TI - Polychlorinated biphenyls influence on hatchability. PMID- 4204150 TI - The metabolism of 14C aflatoxins in laying hens. PMID- 4204151 TI - Increased aflatoxin production by Aspergillus flavus via cobalt irradiation. PMID- 4204152 TI - Influence of polychlorinated biphenyls in the laying hen. PMID- 4204153 TI - Studies of the chick edema disease. 10. Toxicity of chick edema factors in the chick, chick embryo, and monkey. PMID- 4204154 TI - Carriage of Australia antigen by cockroaches. PMID- 4204155 TI - Effect of blood factor deposits in reused dialysers on the dialysance of middle weight molecules. PMID- 4204156 TI - The production of immunosuppressive antisera. PMID- 4204157 TI - [The disappearance curve of horse antilymphocyte globulins labeled with I-131 and I-125 in long term treatment of posttransplantation patients]. PMID- 4204158 TI - Anti-HAA immunity in renal units with a high and low incidence of serum hepatitis. PMID- 4204159 TI - Medical treatment and intrathecal nerve block. PMID- 4204160 TI - [Appendicular diverticulum]. PMID- 4204161 TI - [Antigens and antibodies, circulating in the blood at early stages of experimental hepatocarcinogenesis]. PMID- 4204162 TI - [Mechanism of the resistance of Guerin's carcinoma to thiophosphamide]. PMID- 4204163 TI - [Experience with electron therapy of vulvar neoplasms]. PMID- 4204164 TI - [Sex chromatin in cervix neoplasm cells]. PMID- 4204165 TI - Propranolol given twice daily in hypertension. PMID- 4204166 TI - The effect of different serum concentrations of antimicrobial drugs on the Lactobacillus leichmannii vitamin B12 assay. PMID- 4204167 TI - Memory and the temporal lobe. A review for clinicians. PMID- 4204168 TI - [Proliferation in the spleen of bone marrow-derived cells after injection of immunostimulating bacteria]. PMID- 4204169 TI - Structure, synthesis and external transfer of mucosal immunoglobulins. PMID- 4204170 TI - Does behavior evolve? PMID- 4204171 TI - The problem of comparison in comparative psychology. PMID- 4204172 TI - Problems of comparative psychology. PMID- 4204173 TI - The organization of comparative psychology. PMID- 4204174 TI - Can psychopathology be reinduced in rhesus monkeys? PMID- 4204175 TI - Spinal cord injury: a review of experimental implications for clinical prognosis and treatment. PMID- 4204176 TI - Measurement of liver blood flow in the infant monkey. A comparison of methods. PMID- 4204177 TI - Energy metabolism and intravenous nutrition of premature infants. I. The responses of oxygen consumption, respiratory quotient and substrate utilization to infusion of aminosol-glucose. PMID- 4204178 TI - Immunoglobulins in haemolytic disease of the newborn. PMID- 4204179 TI - Interaction between serum calcium concentration and glucose tolerance in normal and azotaemic patients. PMID- 4204180 TI - Effect of transplantation site on the results of pancreatic islet isografts in diabetic rats. PMID- 4204181 TI - Carcinoembryonic antigen (CEA) in feces and plasma of normal subjects and patients with colorectal carcinoma. PMID- 4204182 TI - Superficial hemosiderosis of the central nervous system. PMID- 4204183 TI - [Results of combination (chemo-surgical) treatment of experimental neoplasms]. PMID- 4204184 TI - Saguinus geoffroyi as a host for Plasmodium vivax. PMID- 4204185 TI - Separation of Toxoplasma gondii trophozoites from mouse exudate cells. Comparison of methods. PMID- 4204186 TI - Preliminary observations of Cebus nigrivittatus (Primates: Cebidae) on the Venezuelan Llanos. PMID- 4204187 TI - Social preference of the squirrel monkey (Saimiri sciureus). PMID- 4204188 TI - New drugs and research: glybenclamide (Daonil). PMID- 4204189 TI - Fontanel size and epiphyseal ossification in neonates with intrauterine growth retardation. Preliminary communication. PMID- 4204190 TI - Digital hypoplasia and anticonvulsants during gestation: a teratogenic syndrome? PMID- 4204191 TI - Hair tissue as a medium for the differential diagnosis of protein-calorie malnutrition: a commentary. PMID- 4204193 TI - Design of a cage for breeding and group behavioural studies of Macaca fascicularis. PMID- 4204192 TI - Vaccinia virus replication in enucleate BSC-1 cells: particle production and synthesis of viral DNA and proteins. AB - The growth of vaccinia virus in monolayers of BSC-1 cells enucleated by centrifugation in the presence of cytochalasin B has been studied. No evidence for the production of infectious virus in these cells was obtained, and the production of virus particles was reduced to 8.3% compared with the yield from cytochalasin-treated, uncentrifuged cells. Virus DNA and early and late polypeptides were synthesized with normal timing in enucleate cells, but in reduced amounts; cleavage of structural polypeptide precursors P4a and Px also occurred in enucleate cells. Factories containing immature virus particles were demonstrated in enucleate cells by electron microscopy; these factories were reduced in number and size compared with those found in cytochalasin-treated, uncentrifuged cells. PMID- 4204194 TI - Sedation of sheep and patas monkeys with ketamine. PMID- 4204195 TI - [Hepatitis B antigen (Australia antigen) in the urine (author's transl)]. PMID- 4204196 TI - Patterns of amyloidosis and their association with plasma-cell dyscrasia, monoclonal immunoglobulins and Bence-Jones proteins. PMID- 4204197 TI - Medicine and Public Affairs. The 1975 Nixon budget for health. PMID- 4204199 TI - [Hypothalamic regulation of water balance]. PMID- 4204198 TI - [Forms of epilepsy difficult to classify]. PMID- 4204200 TI - [Plasma substitutes]. PMID- 4204201 TI - Congenital posterior midline pharyngo-esophageal diverticula. PMID- 4204202 TI - Synthesis of diphtheria tox-gene products in Escherichia coli extracts. AB - In a protein-synthesizing system extracted from E. coli, purified DNA from corynephages betac(tox+) and beta45c was used to direct the in vitro synthesis of diphtheria toxin and of the related nontoxic protein, CRM45, as well as of other beta-phage proteins. When betac(tox+)-DNA or betac-DNA was added to a similar system extracted from the nonlysogenic Corynebacterium diphtheriae strain, C7(s)( )(tox-), neither toxin nor the CRM45 protein was produced, although other beta phage proteins were synthesized in amounts equivalent to those produced in the E. coli system from the same amount of beta-phage DNA. Preliminary experiments suggest that both toxinogenic and nontoxinogenic strains of the diphtheria bacillus contain a factor that specificially blocks expression of the tox gene. Synthesis of toxin and the CRM45 protein in the E. coli system could not be inhibited by relatively high concentrations of inorganic iron, but could be inhibited by extracts from the C7(s)(-)(tox-) strain of C. diphtheriae. PMID- 4204203 TI - Mechanism of DNA replication in Drosophila chromosomes: structure of replication forks and evidence for bidirectionality. AB - The replicating chromosomal DNA in Drosophila melanogaster cleavage nuclei has been visualized in the electron microscope as a serial array of closely spaced replicated regions created by pairs of diverging replication forks. The fine structure of the forks is very similar to that observed for the replication forks of bidirectionally replicating bacteriophage DNAs. However, the mean length of the single-stranded gaps in Drosophila forks is less than 200 nucleotide residues, much shorter than the gaps in phage forks. This difference in gap length corresponds to the observed difference in the size of Okazaki fragments from Drosophila and phage. PMID- 4204204 TI - Calf tendon procollagen peptidase: its purification and endopeptidase mode of action. AB - The procollagen peptidase activity of calf tendon has been purified. The enzyme has a high degree of specificity for native procollagen and converts both pro alpha1 and alpha2, to alpha1 and alpha2, respectively. The purified enzyme is an endopeptidase which excises the amino terminal peptide extensions of the precursor chains in block; the molecular size and amino-acid composition of the excised peptides compare favorably with those predicted in previous reports. Antisera to the enzyme and to procollagen have been prepared and have been used to characterize the enzyme, the enzymatically excised peptides, and the enzyme peptide complex in reaction mixtures. PMID- 4204205 TI - Treatment of aspergillosis with emetine hydrochloride. PMID- 4204206 TI - Mapping human autosomes: evidence supporting assignment of rhesus to the short arm of chromosome No. 1. AB - Rh-negative erythrocytes were found in the blood of an Rh-positive man suffering from myelofibrosis. Nucleated hemopoietic precursors were also circulating in his blood, and these cells had an abnormal chromosome complement from which identifiable chromosome segments had been deleted. Correlation of the serological and cytogenetic findings, combined with previous data, indicates that the Rhesus blood group locus is on the distal portion of the short arm of chromosome No. 1. PMID- 4204207 TI - Otorhinolaryngology. PMID- 4204208 TI - [Clinical microbiology. Observations and problems in the Regional Laboratory. Statens Seruminstitut in Odense hospital in 1963-73]. PMID- 4204209 TI - Cortisone influences developing collaterals. 1. A morphologic study. PMID- 4204210 TI - Electron microscopic findings of human auricular appendages. PMID- 4204211 TI - Suppression of experimental allergic thyroiditis in guinea pigs by homologeous and heterologeous thyroglobulin. PMID- 4204212 TI - Attempt to visualise the ventricular conduction system intravitam. Radiologic in vitro visualisation of the left ventricular conduction system in cow, calf and sheep hearts. PMID- 4204213 TI - [Immunohistologic, cytochemical and electron-microscopic investigations in Zollinger-Ellison-syndrome (author's transl)]. PMID- 4204214 TI - [Experimental myocarditis induced with coxsackie virus in baby mice. Morphology and the problems involved in detection of the virus (author's transl)]. PMID- 4204215 TI - [Histological findings in livers of clinically healthy AuAg (SH) carriers (author's transl)]. PMID- 4204216 TI - Delayed, in vivo hepatic postmorten autolysis. II. Morphological changes in reticulo-endothelial cells. PMID- 4204217 TI - The distortion and disorganization of the glomerulus in progressive Masugi nephritis in the rat. PMID- 4204218 TI - [Autoradiographic investigation of proliferation and polyploidization during CCl4 induced liver regeneration in mice (author's transl)]. PMID- 4204220 TI - [Quantitative model of mouse liver regeneration after CCl4 poisoning (author's transl)]. PMID- 4204219 TI - [Cytological and morphometric investigation of mouse liver regeneration after CCl4 intoxication (author's transl)]. PMID- 4204222 TI - [Conservative and surgical therapy of open malleolar fractures]. PMID- 4204221 TI - Giant mitochondria. II. Induction of matrix enriched megamitochondria in mouse liver parenchymal cells by ethidium bromide. PMID- 4204223 TI - [Motor partial epileptic crises. Study by means of new data processing technics]. PMID- 4204224 TI - [Etiology of late onset epilepsy. Study of 155 cases]. PMID- 4204225 TI - Innovative methods of expanding ambulatory services. PMID- 4204226 TI - [Agar diffusion method for determining tylosin activity and use of this method for titration of an international reference preparation of tylosin]. PMID- 4204227 TI - Carbon nuclear magnetic resonance studies of the histidine residue in alpha-lytic protease. Implications for the catalytic mechanism of serine proteases. PMID- 4204228 TI - Cerebral control of contralateral and ipsilateral arm, hand and finger movements in the split-brain rhesus monkey. PMID- 4204230 TI - The neuronographic and metric study of the dendritic arbours of neurons in the motor cortex of Macaca mulatta at birth and at 24 months of age. PMID- 4204229 TI - The propagation of focal paroxysmal activity in the Macaca mulatta at birth and at 24 months. PMID- 4204231 TI - The role of the postcentral gyrus in the tactile crossed placing reaction in the Rhesus monkey. PMID- 4204233 TI - Effects of an elemental diet on human fecal flora. PMID- 4204232 TI - Mutagenicity of derivatives of the oncogenic purine N-oxides. PMID- 4204234 TI - Longevity therapy with chronic patients in a state hospital. PMID- 4204235 TI - Preparation of sphaeroplasts from Lactobacillus casei by growth with low concentration of benzylpenicillin. PMID- 4204237 TI - The slime of Pseudomonas aeruginosa: biological characterization and possible role in experimental infection. PMID- 4204236 TI - R-factor mediated resistance to penicillins which does not involve a beta lactamase. PMID- 4204239 TI - Experimental studies of rhesus monkeys infected with epizootic and enzootic subtypes of Venezuelan equine encephalitis virus. PMID- 4204238 TI - Diphtheria in the United States, 1959-1970. PMID- 4204240 TI - Antigen-negative meningitis due to group A Neisseria meningitidis. PMID- 4204241 TI - Immunochemical evidence for the transport of haemolymph protein into the cuticle of Manduca sexta. PMID- 4204242 TI - Cathepsin D of rabbit skin: an immunoenzymic study. PMID- 4204243 TI - Elevated antihemophilic factor (AHF, factor VIII) procoagulant activity and AHF like antigen in alcoholic cirrhosis of the liver. PMID- 4204244 TI - Antibody-dependent cellular cytotoxicity to a syngeneic Gross virus-induced lymphoma. PMID- 4204245 TI - Nonspecific suppression of tumor growth by an immune reaction to Listeria monocytogenes. PMID- 4204246 TI - Triglyceride secretion rates: use of Triton WR 1339 in the rhesus monkey. PMID- 4204247 TI - Surface pH changes during and after myocardial ischemia in primates. PMID- 4204248 TI - Sources of gram-negative infection after open-heart surgery. PMID- 4204249 TI - Analysis of bacteriophage phi 29 gene function: protein synthesis in suppressor sensitive mutant infection of Bacillus subtilis. AB - Phage phi29 suppressor-sensitive (sus) mutants of 14 cistrons have been examined for production of (14)C-labeled viral-specific proteins in restrictive infections of Bacillus subtilis. Proteins specified by four cistrons (H, J, L, and N) have been resolved and identified by sodium dodecyl sulfate gel electrophoresis and autoradiography, and fragments of the normal polypeptides were detected. Mutants of six cistrons (C, D, E, F, I, and M) demonstrated two or more missing bands in the gel profiles, and thus some of these gene products may have regulatory functions. Mutation was detected in at least five genes coding for low-molecular weight proteins, but a conditionally lethal mutant in only one of these genes has been isolated. Preliminary evidence that a precursor protein is cleaved to generate the neck appendage structural protein and a low-molecular-weight product has been obtained. PMID- 4204250 TI - Factors influencing the adsorption of bacteriophage 2 to cells of Pseudomonas aeruginosa. AB - Phage 2 adsorbed to Pseudomonas aeruginosa strain BI in 5 mM Tris buffer, providing that cations like Na(+), Mg(2+), or Ca(2+) were present. Adsorption was observed over a broad pH range, reaching a maximum level around pH 7.5, which coincided with the pH required for maximal activity of the phage 2-associated slime polysaccharide depolymerase. Mutants of strain BI and other strains of P. aeruginosa possessing slime layers that were devoid of phage 2 depolymerase substrate were incapable of adsorbing phage 2. On the other hand, those strains containing substrate for the phage 2 depolymerase in the slime layer were capable of adsorbing phage 2. The same relationship of phage depolymerase-substrate interaction to phage adsorption was observed with Pseudomonas phage 8, which possesses a depolymerase that differs in its specificity from the phage 2 depolymerase. The receptor-like activity of purified slime containing the specific substrate for the phage-associated depolymerase was demonstrable by its ability to inactivate phage. However, receptor-like activity or phage inactivation was not observed with those slimes that were devoid of the depolymerase substrate. PMID- 4204251 TI - Bacteriuria and oral contraceptives. Routine health examinations of 12,076 middle class women. PMID- 4204252 TI - [Importance of new immunological methods in diagnosis of bronchopulmonary aspergillosis]. PMID- 4204253 TI - Comparison of phototrap complexes from chromatophores of Rhodospirillum rubrum, Rhodopseudomonas spheroides, and the R-26 mutant of Rhodopseudomonas spheroides. PMID- 4204254 TI - Protection by histidine from inactivation of DNA transforming activity by near ultraviolet light (365 nm) compared with far-ultraviolet light (254 nm). PMID- 4204255 TI - [On hyperosmolar diabetic coma]. PMID- 4204257 TI - Naproxen-metabolism, excretion and comparative pharmacokinetics. PMID- 4204256 TI - Comparative toxicology of naproxen. PMID- 4204258 TI - [Toxic effects of chronic misuse of cannabis]. PMID- 4204259 TI - [Latest achievements in the study of subacute spongious encephalopathies]. PMID- 4204260 TI - [Latency of the L forms of beta-hemolytic streptococci in the tissues of experimentally infected animals]. PMID- 4204261 TI - [Study of chronic forms of arbovirus infections in birds. 1. Experiments with West Nile, Sindbis, Bhandja and Sicilian mosquito fever viruses]. PMID- 4204262 TI - [Use of moderate phages containing the tox gene for the study of the taxonomic position of nontoxigenic corynebacteria related to the species C. diphtheriae of the type gravis]. PMID- 4204264 TI - [Ultrastructural studies in chagas' myocarditis in the mouse (author's transl)]. PMID- 4204263 TI - [Clinical results of synchronised radiotherapy on a theoretical and experimental basis (author's transl)]. PMID- 4204265 TI - [Cytopathogenic effects of Tripanosoma cruzi on MA-104 cells (author's transl)]. PMID- 4204266 TI - Nonspecific agents acting on parasites: synergistic effect of nitrogen mustard and acriflavine on resistance formation. PMID- 4204267 TI - The effect of dietary protein depletion on immunocompetence: the importance of nutritional repletion prior to immunologic induction. PMID- 4204268 TI - Bacterial endocarditis associated with colorectal carcinoma. PMID- 4204269 TI - Parenteral nutrition in the burned child: a study of twenty-six patients. PMID- 4204270 TI - Behaviour of an aziridine alkylating agent in acid solution. PMID- 4204271 TI - Aspartate transcarbamylase from Streptococcus faecalis. Purification, properties, and nature of an allosteric activator site. PMID- 4204272 TI - Aspartate transcarbamylase from Streptococcus faecalis. Reverse reaction and binding studies. PMID- 4204273 TI - Chemical properties of Escherichia coli lysine decarboxylase including a segment of its pyridoxal 5'-phosphate binding site. PMID- 4204274 TI - Allosteric effectors of hemoglobin. Interaction of human adult and fetal hemoglobins with poly(carboxylic acids). PMID- 4204275 TI - Heterogeneity of lobster agglutinins. I. Purification and physiochemical characterization. PMID- 4204276 TI - Heterogeneity of lobster agglutinins. II. Specificity of agglutinin-erythrocyte binding. PMID- 4204277 TI - [Affinities between oxyuris parasites of Hystricidea, Erethizontidea and Dinomyidea rodents. Paleobiographic value]. PMID- 4204278 TI - [Ultrastructural localization of acid phosphatase activity at the beginning of spermatogenesis (spermatogonias and spermatocytes) in Drosophila melanogaster. Preliminary study of multivesicular bodies]. PMID- 4204279 TI - [Characterization of a model of lung pleural boundary and application to the study of tissue compliance of closed respiratory tracts]. PMID- 4204280 TI - [Influence of a sodium phosphonate on calcium renal level in magnesium-deficient rats]. PMID- 4204281 TI - [Insulin binding to membrane fractions of adrenal glands]. PMID- 4204282 TI - [Demonstration by fluorescent antibody technic of a substance immunologically related to LH-RF in hypothalamus and median eminence in mammals]. PMID- 4204283 TI - [Colonization of rudimentary gonads in chick embryos by germinal cells after unilateral mesonephros agenesis]. PMID- 4204284 TI - [Dihydrotestosterone, feminizing hormone in chick embryos]. PMID- 4204285 TI - [Comparative data on acid phosphatase of a yeast of the rhodotorula genus and a yeast of the Saccharomyces genus]. PMID- 4204286 TI - [Homochromatographic analysis of 70 S RNA extracted from murine oncornavirus]. PMID- 4204287 TI - [Development of rabies virus on embryonal cells of the reptile blind-worm, Anguis fragilis L]. PMID- 4204288 TI - [Data concerning immunogenetics and speciation process in primates]. PMID- 4204289 TI - [Influence of circadian rhythm of cell division on the efficacy of cyclophosphamide on sarcoma induced by methylcholanthrene]. PMID- 4204290 TI - [Modification of transplantation antigens (ABO system) carried by lymphocytes from healthy patients or by paralymphoblasts from leukemic patients]. PMID- 4204291 TI - Effects of halothane on left ventricular function and distribution of regional blood flow in dogs and primates. PMID- 4204292 TI - [In vitro intracellular vitality of cicada symbionts and reinfected asymbiontic mycetocyte cultures]. PMID- 4204293 TI - Effect of Na salts of organic acids on acid induced swelling and K loss in Pseudomonas aeruginosa and effect of pH on actions of mercuric, cadmium and zinc salts. PMID- 4204294 TI - Crystalline kidney-bean leucoagglutinin. PMID- 4204295 TI - Influence of membrane lipids on the regulatory properties of UDP glucuronyltransferase. PMID- 4204296 TI - Electroejaculation technique in Macaca mulatta (rhesus monkeys). PMID- 4204297 TI - [Nature and demonstration of hepatitis B--(Australia)-antigen and its antibody]. PMID- 4204298 TI - The use of sensitized latex in the identification of human bloodstains. PMID- 4204299 TI - Iodination (125I) of the apical plasma membrane of toad bladder epithelium: electron-microscopic autoradiography and physiological effects. PMID- 4204300 TI - Varieties of hypothyroidism. PMID- 4204301 TI - [Recommendations for the technic and evaluation of Mycobacterial sensitivity tests]. PMID- 4204302 TI - A comparative study of precipiting serological techniques for the detection of meningococcal polysaccharide. PMID- 4204303 TI - Metabolic inhibition test for the measurement of antibody to Neisseria meningitidis. PMID- 4204304 TI - [Macroglobulinemias. Clinical serology]. PMID- 4204305 TI - Psychological aspects of sudden unexpected death in infants and children. PMID- 4204306 TI - [Quantitative study of immunoglobulin A in human tears]. PMID- 4204307 TI - [Sterilization of biotronic cardiac pacemakers using peracetic acid]. PMID- 4204308 TI - On findings of virus-like structures in uterine cervical carcinoma. PMID- 4204309 TI - Prostaglandin mediated inhibition of noradrenaline release at different nerve impulse frequencies. PMID- 4204310 TI - Electrophysiological study of the gustatory effects of the sweet proteins monellin and thaumatin in monkey, guinea pig and rat. PMID- 4204311 TI - Funduscopic alterations in the rhesus monkey induced by exposure to heavy ions (O+8) 250 MeV nucleon. PMID- 4204313 TI - Congenital gastric diverticulum as a cause of massive hemorrhage. PMID- 4204312 TI - Increased jejunal IgA synthesis in vitro during acute infectious nonbacterial gastroenteritis. PMID- 4204314 TI - An epidemiologic survey of arterial blood pressure in a large male population group. PMID- 4204315 TI - Hepatitis and hepatitis B-antigen in Greenland. PMID- 4204316 TI - Inhibition of in vivo and in vitro epoxidation of aldrin, and potentiation of toxicity of various insecticide chemicals by diquat in two species of fish. PMID- 4204318 TI - The central nervous system pharmacology of an anti-emetic dihydroindolone derivative. PMID- 4204319 TI - Precipitating antibodies for an avian adenovirus in Queensland poultry flocks. PMID- 4204317 TI - Polychlorinated biphenyls (PCBs) as inducers of microsomal enzyme activity in the house fly. PMID- 4204320 TI - Letter: Very small public health risk from flesh of tuberculous cattle. PMID- 4204321 TI - Identification and measurement of the folates in sheep liver. AB - 1. Methods are described for the extraction, separation by ion-exchange chromatography and estimation by microbiological assay of the folates in sheep liver. 2. Injection of [2-(14)C]-pteroylglutamate into a sheep fed on a stock diet led to extensive labelling of chromatographically separable liver folates. About 12% of the label in the liver could not be extracted by the method used. 3. Liver folates were examined in five ewes fed on restricted amounts of a diet of wheaten hay-chaff and gluten and injected weekly with vitamin B(12). Chromatographic separation was followed by microbiological assay with Lactobacillus casei, Streptococcus faecalis R. and Pediococcus cerevisiae both before and after treatment of fractions with conjugase (gamma glutamylcarboxypeptidase). Evidence was obtained that the folates present were predominantly polyglutamate forms of tetrahydropteroylglutamate, 5 methyltetrahydropteroylglutamate and 5- (and 10-) formyltetrahydropteroylglutamates. Differences in the responses of the assay organisms permitted quantitative distinction between these three main classes of folates. 4. Methyltetrahydrofolates were eluted in seven successive peaks that were separated by constant increments in the logarithm of eluant [P(i)]. A similar relationship existed for seven successive peaks of tetrahydrofolate and may also have existed for each of the two series of formyltetrahydrofolates. 5. Based on these and other observations it is proposed that sheep liver folates consist predominantly of the mono- to hepta-glutamates of each of the reduced pteroates identified. The methods employed allowed quantitative determinations to be made of most of the folates present. The predominant forms were hexaglutamates. 6. Four components active for L. casei were detected that could not be identified. Three of them were polyglutamates. PMID- 4204322 TI - Folic acid metabolism in vitamin B12-deficient sheep. Depletion of liver folates. AB - 1. Metabolism of folate was studied in six ewes in an advanced state of vitamin B(12) deficiency as judged by voluntary food intake and in their pair-fed controls receiving vitamin B(12). A group of four animals that were maintained throughout the experiment at pasture was also studied. 2. After 34-40 weeks on the cobalt-deficient diet urinary excretion of formiminoglutamate by four deficient animals was about 3.2mmol/day and this was not significantly decreased by injection of three of them with about 4.5mug of [2-(14)C]folate/kg body weight per day for 5 days. Three days after the last injection retention of [2 (14)C]folate by the livers of the deficient animals (5.5% of the dose) was lower than that of their pair-fed controls (26% of the dose) but there was no evidence of net retention of injected folate in the livers of either group. Urinary excretion of (14)C indicated that renal clearance of folate may have been impaired in very severe vitamin B(12) deficiency. 3. As estimated by microbiological assays total folates in the livers of animals at pasture (12.9mug/g) included about 24% of 5-methyltetrahydrofolate as compared with about 72% of a total of 12.5mug/g in three further ewes fed on a stock diet of wheaten hay-chaff and lucerne-chaff. Liver folates of vitamin B(12)-deficient animals (0.5mug/g) included about 88% of 5-methyltetrahydrofolate as compared with about 51% of a total of 5.2mug/g in pair-fed animals treated with vitamin B(12). 4. Chromatography of liver folates of the pair-fed animals permitted quantitative estimates of the pteroylglutamates present. The results showed that the vitamin B(12)-deficient livers were more severely depleted of tetrahydrofolates and formyltetrahydrofolates than of methyltetrahydrofolates and that as the deficiency developed they were more severely depleted of the higher polyglutamates than of the monoglutamate within each of these classes. Results from animals injected with [2-(14)C]folate indicated an impairment of the exchange between pteroylmonoglutamates and pteroylpolyglutamates in the livers of deficient animals. 5. In vitamin B(12)-deficient animals with food intakes below 200g/day some of the liver folates were not completely reduced and some degradation of pteroylpolyglutamates was detected. The latter condition may have been associated with fatty liver. 6. The results are discussed in relation to current theories of vitamin B(12)-folate interactions. PMID- 4204323 TI - The role of multivalent cations in the uptake and oxidation of glucose by Pseudomonas fluorescens. AB - The effects of Mg(2+), Mn(2+), Ca(2+) and Fe(3+) on the uptake and oxidation of glucose in induced and non-induced Pseudomonas fluorescens cells were studied. Mg(2+) is the most effective single metal ion in the uptake of glucose by the cell, and it functions in membrane stabilization and enzymic activity. Ca(2+) will substitute for Mg(2+), but Mn(2+) and Fe(3+) will not. PMID- 4204325 TI - [An unusual presentation of phakomatosis: congenital sublingual neurofibromatosis (author's transl)]. PMID- 4204324 TI - [Esterase. X. Content and substrate pattern of esterase in fixed tissues (author's transl)]. PMID- 4204326 TI - Effects of colchicine and 2-Br-alpha-ergocryptine-methane-sulfonate (CB 154) on the release of prolactin and growth hormone by functional pituitary tumor cells in culture. PMID- 4204327 TI - Inactivation of protein synthesis stimulating activity in serum by cells. PMID- 4204328 TI - Factors affecting pH-dependent photo-inhibition of division in Euglena gracilis. PMID- 4204330 TI - The effect of eye colour pigments on the action spectrum of Drosophila. PMID- 4204329 TI - The toxic effects of phenoloxidase from the haemolymph of tenebrionid beetles. PMID- 4204331 TI - [Research on the ultrastructure and function of the anal organ of the normal and lethal (l(3)tr) larvae of the Drosophila melanogaster]. PMID- 4204332 TI - Alpha-glycerophosphate dehydrogenase in Drosophila melanogaster: kinetic differences and developmental differentiation of the larval and adult isozymes. PMID- 4204333 TI - [Plasmodium ovale malaria]. PMID- 4204334 TI - [Autopsy in a case of Weil's disease together with a review of 84 others observed in Japan]. PMID- 4204335 TI - 6-Phenyl-4,5-dihydro-3(2H)-pyridazinones. A series of hypotensive agents. PMID- 4204336 TI - Synthesis of pyrimido(4,5-b)(1,4)-7-hydrothiazines related to 7,8 dihydropteridines of biological importance. PMID- 4204337 TI - Thanatophoric dwarfism. PMID- 4204338 TI - Agenesis of the corpus callosum in two sisters. PMID- 4204339 TI - Trisomy 13 in two infants with cyclops. PMID- 4204340 TI - The effect of tanning agents on the permeability of the toad bladder to water and solutes. PMID- 4204342 TI - Studies in the pathogenesis, diagnosis, and treatment of Candida sepsis in children. PMID- 4204341 TI - Innervation of abdominal paraganglia: an ultrastructural study. PMID- 4204343 TI - Synthesis and antimicrobial properties of 17beta-amino-4-aza-5alpha-androstane and derivatives. PMID- 4204344 TI - Structure relationship for binding of sulfonamides and penicillins to bovine serum albumin by fluorescence probe technique. PMID- 4204345 TI - Electrokinetic studies of bacteria. IV. Effect of acridines on Streptococcus faecalis. PMID- 4204346 TI - Pharmacokinetics of pentazocine in the rhesus monkey. PMID- 4204347 TI - Drug absorption in rats pretreated with antibiotics. PMID- 4204348 TI - Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p chlorophenyl)ethane (DDT). PMID- 4204349 TI - Alterations by neomycin of 45Ca movements and contractile responses in vascular smooth muscle. PMID- 4204350 TI - [Clinical use of sorbitol]. PMID- 4204351 TI - [Free amino acids in the blood serum in patients with postgastrectomy syndrome in connection with parenteral feeding with protein hydrolysates]. PMID- 4204352 TI - [Effect of intravenous feeding on the balance of nitrogen, potassium and sodium in the immediate postoperative period]. PMID- 4204353 TI - [Endoscopic diagnosis of diverticula of the esophagus]. PMID- 4204354 TI - [Diagnosis and therapy of angina pectoris at a medium-size hospital]. PMID- 4204355 TI - [Report on the clinical test of the long-term neuroleptic agent penfluridol]. PMID- 4204356 TI - Intragenic somatic recombination in the lozenge cistron of Drosophila. PMID- 4204358 TI - The effect of sympathetic denervation on cerebral CO2 sensitivity. PMID- 4204357 TI - Biochemical genetics of bacterial sporulation. IV. Sequential development of resistances to chemical and physical agents during sporulation of Bacillus subtilis. PMID- 4204359 TI - Stroke surveillance: the concept of stroke team in diagnosis, treatment and prevention. PMID- 4204360 TI - The use of hyperalimentation in patients with potential sepsis. PMID- 4204361 TI - Xenogeneic renal preservation for transplantation in primates. II. Rejection of stored allografts. PMID- 4204363 TI - Rabbit antisera to HL-A9 isolated from normal serum. PMID- 4204362 TI - Separation of the immunosuppressive and glomerular basement membrane-reactive antibodies in horse antiserum to human thymus. PMID- 4204364 TI - [The 80th birthday of Prof. Karel Sobra]. PMID- 4204365 TI - [Occurrence of distemper (febris canum catarrhalis) in CSR (Czech Socialistic Republic)]. PMID- 4204366 TI - [Clinical and etiological aspects of urolithiasis in minks (Lutreola vison)]. PMID- 4204367 TI - [Atropine and adrenaline induction test in the focus of equine infectious anemia]. PMID- 4204368 TI - [Simplification of method of collection of the sheep's rumen fluid]. PMID- 4204369 TI - [Biochemical indicators and reduction activity of ruminal liquor in sheep]. PMID- 4204370 TI - [Effect of low quality silage on the rumen biochemistry in dairy cows]. PMID- 4204371 TI - [Comparison of the effects of some anthelminthics used in ascariasis and heterakiasis of the domestic fowl]. PMID- 4204373 TI - [Use of isotope nephrography in functional examination of dog's kidneys]. PMID- 4204372 TI - [Values of serum transaminases in horses with chronic respiratory tract diseases]. PMID- 4204375 TI - [Diagnostic errors in occupational lead poisoning]. PMID- 4204376 TI - The microbiology of burukutu beer. PMID- 4204374 TI - Behavioural changes in primates and diazepam metabolism. PMID- 4204377 TI - [Inhibitory effect of glucose on T-Mycoplasma]. PMID- 4204378 TI - [Phosphoglucomutase polymorphism in the population of Lower Franconia. (Germany) (author's transl)]. PMID- 4204379 TI - Interspecies variations in small intestinal and hepatic drug hydroxylation and glucuronidation. PMID- 4204381 TI - Neurofibromatosis of the pelvis and bladder. Case report and review of the literature. PMID- 4204380 TI - Thyroid function and dysfunction during pregnancy. PMID- 4204382 TI - [Clinical aspects of tonic seizures. Analysis of 27 personal cases (author's transl)]. PMID- 4204383 TI - [Occurrence of atypical mycobacteria in patients with tuberculosis in selected centers in 1972]. PMID- 4204384 TI - A comparison of in vivo and in vitro microleakage of dental restorations. PMID- 4204385 TI - Spontaneous perforation of a jejunal diverticulum. PMID- 4204386 TI - A 'new' saliva substance, probably inherited, and serologically independent of ABH, Lewis, and Sda blood group substances. PMID- 4204388 TI - Health in the midst of economic development in Taiwan. PMID- 4204387 TI - Genetic association in myocardial infarction. Ethnicity; ABO, Rh, Le, Xg blood groups; G6PD deficiency; and abnormal haemoglobins. PMID- 4204389 TI - Effect of iron deprivation and temperature upon bacterial survival. PMID- 4204391 TI - [Congenital ureteral diverticulum in a newborn infant]. PMID- 4204390 TI - Particulate nature of o-diphenoloxidase in Mycobacterium leprae and assay of the enzyme by the radioisotope technique. PMID- 4204393 TI - [Features specific for lymphatic system disorders in guinea pigs with experimental tuberculosis]. PMID- 4204392 TI - A positive approach to being negative. PMID- 4204394 TI - [Kinetics of bacterial destruction rate as a prognostic indicator in the treatment of tuberculous patients with tuberculostatics]. PMID- 4204395 TI - [Results of bacteriological examination of patients with freshly diagnosed tuberculosis of the lungs]. PMID- 4204396 TI - Ocular coccidioidomycosis. A clinicopathologic case report. PMID- 4204397 TI - A controlled comparison of two fully supervised once-weekly regimens in the treatment of newly diagnosed pulmonary tuberculosis. PMID- 4204398 TI - The differential tuberculin test in tuberculosis patients. PMID- 4204399 TI - Tuberculosis in a patient after renal transplantation. PMID- 4204400 TI - [Immediate results of use of bremsstrahlung betatron radiation of 25 Mev in the treatment of malignant laryngeal neoplasms]. PMID- 4204401 TI - The fine structure of intracerebral vessels. PMID- 4204403 TI - Immunoglobulins in eluates of malignant human tumours. PMID- 4204402 TI - Studies on the interaction between staphylococcal protein a and the fc-region of immunoglobulin G. PMID- 4204404 TI - [In-vitro anaphylactic reaction with the Schultz-Dale method in the detection of Australia antigen (HAA)]. PMID- 4204405 TI - [Detection of healthy carriers of Neisseria meningitidis among the school population of two towns of the province of Rome]. PMID- 4204406 TI - Alpha1-fetoprotein and liver-specific antigen in viral hepatitis type B. PMID- 4204407 TI - [Study in rats of the effects of protein supplementation of a typical diet of a rural community in Guatemala]. PMID- 4204408 TI - [Diet of the preschool child in rural El Salvador]. PMID- 4204410 TI - Sex differences, environmental complexity, and mother-infant relations. PMID- 4204411 TI - Differential effects of amygdalectomy in male and female nonhuman primates. PMID- 4204412 TI - Contrasting adult male roles in different species of nonhuman primates. PMID- 4204413 TI - Male-female residence arrangements and political power in human hunter-gatherers. PMID- 4204414 TI - Male-female, female-female, and male-male sexual behavior in the stumptail monkey, with special attention to the female orgasm. PMID- 4204415 TI - The effect of blood on disinfection of surgeons' hands. PMID- 4204416 TI - Quantitation of C3PA (properdin factor B) and other complement components in diseases associated with a low C3 level. PMID- 4204417 TI - Heavy chain subclass of human anti-platelet antibodies. PMID- 4204418 TI - Breakdown of noncollagenous chondromucoprotein matrix by leukocyte lysosome granule lysates from guinea pig, rabbit, and human. PMID- 4204419 TI - Increased bactericidal activity by non-specific stimulation of lymphoid cells- experiments in vivo with concanavalin A. PMID- 4204420 TI - The early immune response to Mycobacterium lepraemurium in inbred mice and rats. PMID- 4204421 TI - Incidence of nuclear antibodies in patients and in related and unrelated groups from a community with a "microepidemic" of systemic lupus erythematosus. PMID- 4204422 TI - Insulinotrophic drugs. Effect on intestinal abosorption of sugar. PMID- 4204423 TI - Insulin degradation. VI. Feedback control by insulin of liver glutathione-insulin transhydrogenase in rat. PMID- 4204424 TI - Serum enzyme changes in diabetic ketoacidosis. PMID- 4204425 TI - Two forms of the DNA ligase of human cells. PMID- 4204426 TI - [The growth of avian coccidia in the developing chick embryo and in cultured cells (author's transl)]. PMID- 4204427 TI - [Studies of the criteria of chemoresistance to rifampicin and ethambutol]. PMID- 4204428 TI - [Bacteriological investigations made by repeated periodic seedings, for 4 years, in recently detected nodular pulmonary tuberculosis in patients returning to work]. PMID- 4204429 TI - [Diagnostic difficulties in a case of bronchopulmonary aspergilloma]. PMID- 4204430 TI - Screening for alpha 1-antitrypsin deficiency. PMID- 4204431 TI - Neuroendocrine relationships in farm animals: a review. PMID- 4204432 TI - Control of deoxyribonucleic acid synthesis in a Bacillus subtilis mutant temperature sensitive for initiation of chromosome replication. AB - We used a Bacillus subtilis mutant described previously, which is temperature sensitive for initiation of replication. The inhibition of deoxyribonucleic acid synthesis occurring at 45 C was shown to be reversed when the temperature is lowered even in the absence of protein synthesis. If the bacteria are returned to 30 C, after a prior period at 45 C, they are able to initiate the first round of replication in the presence of chloramphenicol, but the initiation of the second round still requires protein synthesis. This paper shows that the proteins necessary to initiate the second round of replication can be present in bacteria long before this round is initiated. In addition, the appearance of these proteins seems to be influenced by the length of the previous 45 C period. Although similar reinitiation kinetics are observed at 30 C after prior 45 C periods of 30 or 65 min, the ability to initiate the second round without further protein synthesis appears much earlier after a longer exposure at 45 C. To explain these results, a hypothesis is presented which assumes that two different proteins are both necessary for initiation. Only one of these proteins could be accumulated at 45 C during the inhibition of deoxyribonucleic acid synthesis. A peculiarity of initiation material in mutant Ts 37 is that it may be active at 45 C if it has been exposed previously at 30 C. PMID- 4204433 TI - Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes. AB - A strain of Streptococcus faecalis var. zymogenes, designated JH1, had high-level resistance to the antibiotics streptomycin, kanamycin, neomycin, erythromycin, and tetracycline. These resistances were lost en bloc from approximately 0.1% of cells grown in nutrient broth at 45 C. The frequency of resistance loss was not increased by growth in the presence of the "curing" agents acriflavine or acridine orange, but after prolonged storage in nutrient agar 17% of cells became antibiotic sensitive. Covalently closed circular deoxyribonucleic acid (DNA) molecules were isolated from the parental strain and from antibiotic-sensitive segregants by using cesium chloride-ethidium bromide gradients. DNA molecular species were identified by using neutral sucrose gradients. Strain JH1 contained two covalently closed circular DNA species of molecular weights 50 x 10(6) and 38 x 10(6). An antibiotic-sensitive segregant, strain JH1-9, had lost the larger molecular species. A second sensitive segregant, strain JH1-5, had also lost the larger molecular species but a new molecular species of approximate molecular weight 6 x 10(6) was present. The antibiotic resistances that were curable from the parental strain were transferred to antibiotic-sensitive strains of S. faecalis and to strain JH1-9, during mixed incubation in nutrient broth at 37 C. Data to be described are interpreted to suggest that the transfer is by a conjugal mechanism. Analysis of the plasmid species in recipient clones showed that all had received the plasmid of molecular weight 50 x 10(6). Strain JH1-5 was not a good recipient. Analysis of one successful recipient clone of JH1-5 revealed that it had gained the 50 x 10(6) molecular weight plasmid but lost the 6 x 10(6) molecular weight species. These data are interpreted to mean that the multiple antibiotic resistance is borne by a transferable plasmid of 50 x 10(6) molecular weight, and that in clone JH1-5 this plasmid suffered a large deletion leaving only a 6 x 10(6) remnant which was incompatible with the complete replicon. PMID- 4204434 TI - C4-dicarboxylate transport in Bacillus subtilis studied with 3-fluoro-L-erythro malate as a substrate. AB - Bacillus subtilis cells grown in yeast extract medium accumulated 3-fluoro-l erythro-[1,2-(14)C(2)]malate more than 30-fold from the surrounding medium. No metabolic products derived from 3-fluoro-l-erythro-malate could be detected in these cells. l-Malate competitively inhibited transport of 3-fluoro-l-erythro malate. This malate analogue was itself a competitive inhibitor of l-malate uptake. Cells that had been grown in yeast extract supplemented with 5 mM l malate showed a 10-fold increased affinity towards 3-fluoro-l-erythro-malate relative to cells grown in yeast extract medium with no added malate. Our results suggest that two transport systems for l-malate can be induced in B. subtilis. The first of these systems seems to effect uptake of C(4)-dicarboxylates (l malate, succinate, and fumarate) in yeast extract medium. The second transport system (or possibly a modification of the first transport system) seems to be induced by addition of l-malate to this medium and is also functioning in malate minimal medium. PMID- 4204435 TI - L-amino acid dehydrogenases in Bacillus subtilis spores. AB - The presence of two kinds of l-amino acid dehydrogenase in resting spores of Bacillus subtilis was indicated. One of them was l-alanine dehydrogenase, which used only l-alanine as a substrate, and the other was nonspecific dehydrogenase, which used l-valine, l-isoleucine, l-leucine, and l-alanine (slightly) as substrates. Several properties of these dehydrogenases were compared. PMID- 4204436 TI - Buoyant density heterogeneity in spores of Bacillus subtilis: biochemical and physiological basis. AB - The biochemical and physiological basis of density heterogeneity in Renografin of Bacillus subtilis W23 spores was determined by analysis of metals, macromolecules, and dipicolinic acid in the two density classes of the population. Germination rate and heat resistance were measured in both density classes. Atomic absorption spectrophotometry revealed that heavy spores (density = 1.335 g/ml) have 30% more calcium than light spores (density = 1.290 g/ml). Other metals found in greater amounts in heavy spores were manganese and potassium. However, light spores had more sodium than heavy spores. The amounts of carbohydrates, nucleic acids, and proteins were the same in both types of spores, but light spores contained more lipids, whereas heavy spores had 30% more dipicolinic acid than light spores. Calcium and lipid were excluded as causes of the heterogeneity in density in that alteration of their contents in spores did not detectably affect the density of these spores. Spores of two densities were genetically similar. Furthermore, light density spores arose earlier during sporulation than heavy spores as determined by releasing refractile forespores at various times during sporulation. We concluded that light spores represent an incomplete stage in development because they became heavy when reinoculated into spent sporulation medium. This must involve the additional accretion or synthesis of dipicolinic acid. PMID- 4204437 TI - Precursor of 5S ribosomal ribonucleic acid in the blue-green alga Anacystis nidulans. AB - The maturation of 5S ribosomal ribonucleic acid (rRNA) in the obligately photoautotrophic unicellular blue-green alga Anacystis nidulans has been studied by using polyacrylamide gel electrophoresis and T1 ribonuclease oligonucleotide analysis. A. nidulans mature 5S rRNA (m5) is of approximately the same molecular weight as the 5S rRNA of Escherichia coli, and is derived by cleavage of a precursor (p5) containing a few (three to six) additional nucleotides. Some of these additional nucleotides occur at the 5' end of the precursor molecule; others may occur at the 3' end. Kinetic experiments indicate that precursors of mature 5S rRNA larger than p5 either do not exist or are very transient in A. nidulans. These results are discussed in relation to those obtained with other prokaryotes. PMID- 4204438 TI - Beta-D-phosphogalactoside galactohydrolase from Streptococcus cremoris HP: purification and enzyme properties. AB - beta-d-phosphogalactoside galactohydrolase (beta-PGal) was isolated and purified from cell-free extracts of Streptococcus cremoris HP to apparent homogeneity to gel electrophoresis. Using the chromogenic o-nitrophenol-beta-d-galactopyranoside 6-phosphate as substrate, the purified enzyme exhibited a specific activity of 18.71 U/mg of protein and K(m) and V(max) values of 5.88 x 10(-4) M and 23.8 mumol of o-nitrophenol liberated per min per mg of protein, respectively. d Galactose-6-phosphate was a weak competitive inhibitor of beta-PGal. Activity was relatively heat resistant and was maximal from pH 5.0 to 8.0 and over a temperature range of 45 to 52 C. Dithiothreitol, ethylenediaminetetraacetic acid, and citrate stimulated beta-PGal activity, whereas Mg(2+), Li(1+), and p hydroxymercuribenzoate were inhibitory. Molecular weight of the enzyme was estimated at 6.76 x 10(4). Amino acid composition was similar to other beta phosphogalactosidases previously investigated, with the exception that the S. cremoris enzyme contains a small amount of half cystine. PMID- 4204439 TI - Effect of viscosity on bacterial motility. AB - The behavior of a number of motile flagellated bacteria toward viscosity characteristics of their fluid environments was observed. All showed an increase in velocity (micrometers per second) in more viscous solutions. Velocity reached a maximum at a characteristic value, however, and thereafter decreased with higher viscosities. Peritrichously flagellated bacteria had maximum velocities at higher viscosities than polarly flagellated bacteria. Effects of temperature, and possible utilization of chemical constituents in the viscous solutions, were studied and found to be negligible factors under the experimental conditions used. Different agents produced the same phenomenon, thus indicating that there probably were no chemically induced metabolic effects. Loss of available water and the possibility of a variable energy supply to the flagellar propulsive system were considered but are believed minimal. Theoretically derived thermodynamic equations were utilized and suggest that the conformation of the flagellar helix affects efficiency of propulsion. Such a relationship between helix waveform and velocity was experimentally observed with Thiospirillum jenese. PMID- 4204440 TI - Transcription from the complementary deoxyribonucleic acid strands of Bacillus subtilis during various stages of sporulation. AB - The messenger ribonucleic acid (mRNA) pattern of log-phase and sporulating cells of Bacillus subtilis has been analyzed by deoxyribonucleic acid (DNA)-RNA hybrid studies with the complementary-strand fragments of DNA. Approximately 80% of the mRNA of log-phase and sporulating cells from stages I, III, and IV hybridizes with the heavy DNA fragments, and 20% hybridizes with the light DNA fragments. Hybrid competition studies indicated that there was either a greatly reduced rate of transcription or a turn-off of some log-phase genes during the sporulation stages. However, a significant amount of log-phase gene transcription occurred even at late stages of sporulation. Similar studies indicate a significantly increased rate of transcription or a turn-on of sporulation phase genes during the latter stages of sproulation. There is a sequential increase in the amount of sporulation-specific transcription from both complementary-strand fragments of DNA. These results indicate that the RNA polymerase population in sporulating cells can transcribe both log-phase and sporulation-phase genes. PMID- 4204441 TI - Inhibition of the Bacillus subtilis membrane-bound D-alanine carboxypeptidase by 6-aminopenicillanic acid covalently coupled to sepharose. AB - An insoluble penicillin derivative, 6-aminopenicillanic acid covalently coupled to Sepharose, was used to investigate the location of the d-alanine carboxypeptidase in the Bacillus subtilis membrane. Only 50% of the enzymatic activity in protoplasts and 74% of that in purified membranes was sensitive, although the purified enzyme could be inhibited completely by the resin. These results suggest that a minimum of 50% of the d-alanine carboxypeptidase exists on the outer face of the bacterial membrane. PMID- 4204443 TI - Phycobilisomes in blue-green algae. AB - Fifteen species of freshwater blue-green algae, including unicellular, filamentous, and colonial forms, were subjected to a variety of fixatives, fixation conditions, and stains for comparison of the preservation of phycobilisomes. Absorption spectra of the corresponding in vivo and released photosynthetic pigments, in 10 of the species that were maintained in culture, demonstrated the presence of phycocyanin in all 10 species and phycoerythrin in only 2 of them. Spectroscope and electron microscope evidence was obtained for localization of phycobiliproteins in phycobilisomes of Nostoc muscorum. Phycobilisomes were observed in all species examined in situ, strenghening the hypothesis that phycobilisomes are common to all phycobiliprotein-containing photosynthetic blue-green algae. PMID- 4204442 TI - Degradative effect of phenol on endotoxin and lipopolysaccharide preparations from Serratia marcescens. AB - It has been established that the well-known deproteinizing action of hot 45% aqueous phenol on whole cells or isolated and purified endotoxin of Serratia marcescens 08 is caused by the cleavage of a phenol-sensitive linkage within the lipid moiety. As a result of this degradation, both the lipopolysaccharide and simple protein fragments retained a part of the lipid moiety. Although not proceeding at the same fast rate as the cleavage of the lipid moiety, such phenol treatment also caused a partial hydrolysis of the O-specific side chain and ester bound fatty acids. Hydrolysis of the O-specific side chain accounted for 5% of the lipopolysaccharide and that of ester-bound fatty acids accounted for 11% of the total fatty acid content after 60 min of treatment. It is suggested that the presence of these degradation products is one of the main causes of the heterogeneity of endotoxin and lipopolysaccharide preparations. PMID- 4204444 TI - Mutant of Bacillus subtilis lacking exo-beta-N-acetylglucosaminidase activity. AB - A procedure for the isolation of exo-beta-N-acetylglucosaminidase mutants, by using a plate assay method incorporating a fluorescent substrate, has been developed. A mutant lacking exo-beta-N-acetylglucosaminidase activity has been isolated and shown to grow, divide, autolyze, and sporulate as well as the parental strain. PMID- 4204445 TI - Mutant of Azotobacter vinelandii that hyperproduces nitrogenase component II. AB - A mutant strain of Azotobacter vinelandii that is unable to fix N(2) produces high levels of nitrogenase component II. Activities of revertants from this mutant strain indicate that a single genetic lesion is responsible for both hyperproduction of component II and the inability to produce component I. PMID- 4204446 TI - Penicillin binding components in Bacillus subtilis during sporulation. AB - The penicillin binding components of sporulating Bacillus subtilis 3610 were compared with those of the vegetative organism. No qualitative difference in binding components was observed. The total binding, however, varied with the phase of sporulation. PMID- 4204447 TI - D-alanine carboxypeptidase and cell wall cross-linking in Bacillus subtilis. AB - Inhibition of d-alanine carboxypeptidase in Bacillus subtilis by 95% caused no measurable change in the degree of cross-linking of the peptidoglycan. PMID- 4204448 TI - Maturation of spatial delayed responses to auditory cues in kittens. PMID- 4204449 TI - Studies of cell-mediated immunity and allergy in protein energy malnutrition. I. Cell-mediated delayed hypersensitivity. PMID- 4204450 TI - Studies of cell-mediated immunity and allergy in protein energy malnutrition. II. Immediate hypersensitivity. PMID- 4204451 TI - [Correction of nitroglycerine angiodystonias with menthol]. PMID- 4204452 TI - [Indication and technique of treatment with aerosols of drugs in a fine mist in long term therapy of chronic bronchitis (author's transl)]. PMID- 4204453 TI - [Antibiotics in the treatment of chronic bronchitis (author's transl)]. PMID- 4204454 TI - [Practical performance of corticoid-therapy in diseases of the respiratory tract (author's transl)]. PMID- 4204455 TI - [Drug prevention of recurring urolithiasis]. PMID- 4204457 TI - [Radiotherapy of low-differentiated prostatic carcinomas. Preliminary report]. PMID- 4204456 TI - [Clinical significance of prostatic cytology and its diagnostic possibilities]. PMID- 4204458 TI - [Surgery of priapism]. PMID- 4204459 TI - [Immunoelectrophoresis of the ejaculate. Possibilities in the differential diagnosis of infectious and noninfectious adnexae diseases]. PMID- 4204460 TI - [Urination and transport of semen. Tasks of the Wolffian duct]. PMID- 4204461 TI - [Surgery of malignant tumors in solitary or residual kidney]. PMID- 4204462 TI - [Transrenal kidney fistula as emergency surgery in urologic diseases]. PMID- 4204463 TI - [Long-term extracorporeal circulation using membrane oxygenators]. PMID- 4204464 TI - [Morphological aspects of atypical mycobacterium infections in the mouse]. PMID- 4204466 TI - [Post-traumatic epilepsy following depression fractures of the skull]. PMID- 4204467 TI - [Value of mandelamine in the prolonged treatment of urinary infections caused by escherichia coli]. PMID- 4204468 TI - [Cytophotometric study of protein substances in pyramidal neurons of the mammalian cerebral cortex]. PMID- 4204469 TI - [Association of marker chromosomes in monkeys. I. Frequency of association of nucleolus-forming chromosomes in lymphocyte cultures exposed to different radiation doses and quantitative analysis of nucleoli]. PMID- 4204471 TI - [Ultrastructure of stellate neurons of the cat and monkey cerebral cortex]. PMID- 4204470 TI - [Biochemical mechanisms of aging of nucleated and non-nucleated erythrocytes]. PMID- 4204472 TI - [Effect of alkylating agents on codling moth ovarioles]. PMID- 4204474 TI - [The ontogenesis of the limbic region of the cortex in man and lower simians]. PMID- 4204475 TI - [Psychopathologic characteristics of the period between seizures in school-age children having epilepsy with a preponderance of petit mal seizures]. PMID- 4204476 TI - [Multivarious evoked potential studies for the qualification of central nervous adaptation processes under the influence of stress in Rhesus-macaca]. PMID- 4204477 TI - Effect of some factors on the biological activity of measles virus. PMID- 4204478 TI - [Hypotension in pregnant women]. PMID- 4204479 TI - Polychlorinated biphenyls in solid waste and solid-waste-related materials. PMID- 4204481 TI - [Methods of evaluation of protein-calorie-nutritional status in preschool children of various socioeconomic classes. Nutritional repercussion of measles in chronically undernourished children]. PMID- 4204482 TI - Letter: Iron absorption from skim milk enriched with iron glycerophosphate. PMID- 4204480 TI - Effect of two isomeric tetrachlorobiphenyls on rats and their hepatic enzymes. PMID- 4204483 TI - [Effects of amino acid imbalanced diets: their projections in human nutrition]. PMID- 4204484 TI - [Evaluation of diets of families and preschool children by using different methods and technics. Rural area of Nicaragua]. PMID- 4204485 TI - The immune response of malnourished subjects with special reference to measles. PMID- 4204486 TI - [Metabolic products of microorganisms. 122. Relations between macrotetrolid production and K+ transport of Streptomyces griseus (author's transl)]. PMID- 4204487 TI - Pigment production by Pseudomonas reptilivora. I. Effect of iron concentration in culture media. PMID- 4204488 TI - Osseous changes in congenital toxoplasmosis. PMID- 4204489 TI - Hepatitis B antigen in a leprosy hospital. AB - A survey of hospital patients with lepromatous and with tuberculoid leprosy showed 5% of the former and 6.3% of the latter to be carriers of hepatitis B antigen. These findings contradict the hypothesis of a genetically determined predisposition; opportunity for infection appears rather to be the determining factor. It was also found that (1) the number of carriers was higher among patients staying longer in hospital; (2) titres of antigen in patients with lepromatous leprosy were higher than in those with tuberculoid leprosy or in controls; and (3) antigen titres measured twice at an interval of 4 months indicated that the carrying of hepatitis B antigen in patients with leprosy is stable and persistent. PMID- 4204490 TI - Immunogenicity of purified, inactivated chikungunya virus in monkeys. AB - Chikungunya (CHIK) virus, harvested from infected BHK-21 cell cultures and highly purified by a method combining zinc acetate precipitation, Sephadex-Sepharose column chromatography, and sucrose density gradient centrifugation, was subjected to ultraviolet (UV) irradiation and treatment with formalin. Inactivation of the virus by UV light was apparently a first-order reaction. The virus treated with 0.05% formalin at 4 degrees C was inactivated completely after 7 weeks, but when treated with 0.025% formalin retained its plaque infectivity at least 17 weeks. Both UV- and formalin-inactivated viruses induced production of anti-CHIK neutralizing antibodies in Japanese monkeys with no preimmune antibodies. Judging by the titres of antibodies produced, the immunogenic effect of the UV-irradiated virus was superior to that of the formalin-treated virus. PMID- 4204491 TI - A search for the epidemic typhus agent in Ethiopian ticks. AB - The presence of antibodies to Rickettsia prowazeki in domestic animals from several parts of Africa, and the isolation of this rickettsia from the blood of goats and sheep and from ticks off cattle or camels in Ethiopia, led to the hypothesis that R. prowazeki in nature may occur in an extrahuman cycle involving ticks and domestic animals. This study attempted to recover R. prowazeki from 2 624 ticks (4 genera, 10 species) collected in central and southern Ethiopia. The ticks were examined by the haemolymph test and by the injection of tissues into guineapigs. No strains of typhus rickettsia were received and there was no serologic evidence suggesting the presence of this agent in any of the ticks examined. One Amblyomma cohaerens contained an organism that reacted specifically with fluorescing antibodies against R. prowazeki; attempts to isolate and identify this agent failed. Fifty-seven (2.2%) Amblyomma ticks (26 A. gemma, 17 A. variegatum, 14 A. cohaerens) were infected with rickettsiae of the spotted fever group, and probably represented R. conori or closely related rickettsial agents. PMID- 4204492 TI - Vaccination of Rhesus monkeys (Macaca mulatta) against Plasmodium knowlesi by the use of nonviable antigen. AB - This study was part of a long-term project with the ultimate goal of developing a malaria vaccine for use in man. Rhesus monkeys that had been vaccinated with a nonviable antigen given in combination with Freund's adjuvant were protected against a normally lethal challenge of Plasmodium knowlesi. Use of the antigen alone or in combination with other adjuvants was not successful. The fact that monkeys were protected against an infection that is normally lethal suggests that a similarly prepared antigen might be of use against malaria in human beings. PMID- 4204493 TI - Studies of folic acid compounds in nature. 3. Folic acid compounds in cabbage. PMID- 4204494 TI - Effect of amino acid starvation on UV sensitivity of Lactobacillus acidophilus cells. PMID- 4204495 TI - Immunochemical studies on mannans of the genus Saccharomyces. Group of Torulaspora species. PMID- 4204496 TI - Regulation of biosynthesis of secondary metabolites. XV. Isolation and characterization of auxotrophic mutants in Streptomyces aureofaciens. PMID- 4204497 TI - Quantitative determinations of complement components and immunoglobulins in tears and aqueous humor. PMID- 4204498 TI - The nerve-fiber layer of the primate retina: an autoradiographic study. PMID- 4204499 TI - Direct determination of carbaryl by gas-liquid chromatography using electron capture detection. PMID- 4204500 TI - Photoreduction of 4,4'-dichlorobiphenyl. PMID- 4204501 TI - Report on drugs, acidic and neutral nitrogenous. PMID- 4204502 TI - Report on multiresidue methods (interlaboratory studies). PMID- 4204503 TI - Reverse phase thin layer chromatography of some aroclors, halowaxes, and pesticides. PMID- 4204504 TI - Ceramic-coated subperiosteal implants. II. Clinical and histologic evaluations. PMID- 4204505 TI - The activation of mononuclear phagocytes in vitro: immunologically mediated enhancement. PMID- 4204506 TI - Neurogenic influence on pulmonary compliance. PMID- 4204508 TI - [Tobramycin, a new antibiotic effective against pseudomonas pyocyahea]. PMID- 4204507 TI - Pharmacologic increases in erythrocyte 2,3-diphosphoglycerate for therapeutic benefit. PMID- 4204509 TI - [Hemolytic disease of the newborn due to sensitization to antigen c of Rh system]. PMID- 4204510 TI - [Immunization anemia in infants with a history of hemolytic disease of the newborn]. PMID- 4204511 TI - Criteria for an animal model of alcoholism. PMID- 4204512 TI - Heart rate and respiratory rate changes during drug-induced impairment in a conditioned avoidance task in monkeys. PMID- 4204513 TI - A comparison of d-amphetamine, l-amphetamine, and methamphetamine self administration in rhesus monkeys. PMID- 4204514 TI - Evidence for ascending noradrenergic mediation of hypothalamic hyperphagia. PMID- 4204515 TI - A review of methods to induce alcohol addiction in animals. PMID- 4204516 TI - Periosteal new bone formation (periosteal neostosis) in renal osteodystrophy. Relationship to osteosclerosis, osteitis fibrosa, and osteoid excess. PMID- 4204517 TI - The relationship of NSD to reactions and complications following treatment for malignant uterine cervical neoplasms. PMID- 4204518 TI - Rickettsioses in Dalmatia (Yugoslavia). PMID- 4204519 TI - Australia antigen in patients with viral hepatitis. PMID- 4204520 TI - [Detoxication mechanisms of organophosphate and carbaminate insecticides]. PMID- 4204521 TI - [Toxic properties of some species of fungi isolated from foodstuffs of Polish origin in the years 1969-1970. I. Aspergillus flavus]. PMID- 4204522 TI - Sciatic nerve entrapment by ectopic bone after posterior fracture-dislocation of the hip. PMID- 4204523 TI - On T-cell-mediated cytotoxicity. PMID- 4204524 TI - New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression. PMID- 4204525 TI - Human uromucoid. I. Quantitative immunoassay. PMID- 4204526 TI - Experimental techniques for testing the sensitivity of bladder tumours to antineoplastic drugs. PMID- 4204527 TI - Functional units of Streptomyces hyphae, equivalent with prokaryotic cells. PMID- 4204528 TI - [Comparative study of bacterial thermophily in the genus Bacillus (author's transl)]. PMID- 4204529 TI - [Disappearance of Jacksonian epileptic seizures after removal of an osteoma of the frontal sinuses]. PMID- 4204530 TI - A simple passive hemagglutination-inhibition technic for determination of fibrin degradation products and fibrinogen. PMID- 4204531 TI - Another example of anti-D in a D-positive patient. PMID- 4204532 TI - Isolation of Neisseria meningitidis from the vagina and cervix. PMID- 4204533 TI - Aspergillus myocarditis. PMID- 4204534 TI - Heritability estimates and genetic and environmental correlations for the human immunoglobulins G, M, and A. PMID- 4204535 TI - Blood groups and immunoglobulin groups in Trio and Wajana Indians from Surinam. PMID- 4204536 TI - Position of the Duffy locus on chromosome 1 in relation to breakpoints for structural rearrangements. PMID- 4204537 TI - Evolving health delivery systems and older people. PMID- 4204538 TI - The fastest growing minority: the aging. PMID- 4204539 TI - Health services: their success and failure in reaching older adults. PMID- 4204540 TI - Health status of older people: cross-national implications. PMID- 4204541 TI - Rifampin in initial treatment of pulmonary tuberculosis. A.U.S. Public Health Service tuberculosis therapy trial. PMID- 4204542 TI - Osteomyelitis caused by concurrent infection with Mycobacterium tuberculosis and Blastomyces dermatitidis. PMID- 4204543 TI - Bacteriocin-typing of Mycobacterium tuberculosis. PMID- 4204544 TI - [A new diagnosticly utilizable culture property of Dermatophilus congolensis]. PMID- 4204545 TI - Thyroxine transport and metabolism in methadone and heroin addicts. PMID- 4204546 TI - The plasminogen activator of vampire bat saliva. PMID- 4204547 TI - The relationship between the urethral flora and urinary infection in the catheterised male. PMID- 4204548 TI - Effect of phenobarbitone on plasma (14C)bilirubin clearance in patients with unconjugated hyperbilirubinaemia. PMID- 4204549 TI - Recombination at the bar locus in an inverted attached-X system in Drosophila melanogaster. AB - Recombination at the Bar locus in Drosophila melanogaster was investigated in an inverted attached-X system which enhanced the frequency of homozygosis for the Bar region. Females among the progeny of homozygous B mothers were searched for changes of B to BB and to B(+). Marker genes were followed and exceptional half tetrads were analyzed in regard to two hypotheses: that of exchange between obliquely synapsed members of the duplication, which is associated with exchange of outside markers, and that of intrachromosomal exchange, which does not involve recombination of markers.-Recombinant exceptions of B(+) /BB genotype, carrying the outside marker combinations predicted on the hypothesis of exchange between obliquely synapsed duplication members, were encountered repeatedly. It is established that B(+) and BB strands are reciprocal products of the same event. Twelve nonrecombinant exceptional strands were isolated; ten of these were B(+) and two were BB. Only one of the nonrecombinant half-tetrads offered the opportunity to test the prediction of reciprocity of the intrachromosomal event. Analysis showed the exceptional female to be of the constitution BB/B, a type not expected on the hypothesis. While it could have arisen through some kind of copy error in the repair of a chromatid break, a valid test of the hypothesis of intrachromosomal exchange must rest on the isolation and analysis of more cases of the appropriate exceptional genotype.-In several cases Bar changes were found to be associated with aberrations; all but one of these involved spontaneous, cytologically identifiable deletions. PMID- 4204550 TI - Heterogeneity of echovirus type 17: comparison of the two lines of the prototype strain. PMID- 4204551 TI - Unsaturated fatty acid synthesis is not required for induction of lactose transport in Escherichia coli. PMID- 4204552 TI - Purification and properties of an endo-beta-N-acetylglucosaminidase from Streptomyces griseus. PMID- 4204553 TI - The release of intact oligosaccharides from specific glycoproteins by endo-beta-N acetylglucosaminidase H. PMID- 4204554 TI - The structural gene for O-acetylserine sulfhydrylase A in Salmonella typhimurium. Identity with the trzA locus. PMID- 4204555 TI - Isolation of a second form of calsequestrin. PMID- 4204556 TI - Morphology of the inferior olivary complex of the rhesus monkey (Macaca mulatta). PMID- 4204557 TI - Comparison of the infectivity and pathogenicity of six species of African schistosomes and their hybrids. 2. Baboons. PMID- 4204558 TI - Isolation and characterization of a blood P1 active carbohydrate antigen of Echinococcus granulosus cyst membrane. PMID- 4204559 TI - A potent non-peroxidase glycoprotein immunogen in commercial horseradish peroxidase. PMID- 4204560 TI - A functional abnormality of the fifth component of complement (C5) from human serum of individuals with a familial opsonic defect. PMID- 4204561 TI - Fractionation of sera from operationally tolerant rats by DEAE cellulose chromatography; evidence that serum blocking factors are associated with IgG. PMID- 4204563 TI - Autoimmune murine thyroiditis. IV. Localization of genetic control of the immune response. PMID- 4204562 TI - Rabbit secretory IgA: identification and genetic control of two allotypes of secretory component. PMID- 4204564 TI - Counterimmunoelectrophoresis with adenovirus type-specific anti-hemagglutinin sera as a rapid diagnostic method. PMID- 4204565 TI - Differential contributions of spinal pathways to body representation in postcentral gyrus of Macaca mulatta. PMID- 4204566 TI - Response characteristics of single cells in the monkey superior colliculus following ablation or cooling of visual cortex. PMID- 4204567 TI - Reconstruction of population response to a vibratory stimulus in quickly adapting mechanoreceptive afferent fiber population innervating glabrous skin of the monkey. PMID- 4204568 TI - Evidence for an endogenous antigen in the adjuvant arthritic rat. PMID- 4204569 TI - Adrenal function in normal infants and in marasmus and kwashiorkor: plasma aldosterone concentration and aldosterone secretion rate. PMID- 4204571 TI - Letter: Wheat farmer's asthma in Australia. PMID- 4204570 TI - [External counterpulsation]. PMID- 4204572 TI - [Parasitic Ciliophora. I. Pectenita golikowi gen. et sp. n. (Entodiscidae fam. n.) from Mizuhopecten yessoensis]. PMID- 4204573 TI - Glucose intolerance in infants of very low birth weight. I. Incidence of hyperglycemia in infants of birth weights 1,100 grams or less. PMID- 4204574 TI - Total and free thyroid hormone concentrations in the neonatal period. PMID- 4204575 TI - Custody of the myelodysplastic child: implications for selection for early treatment. PMID- 4204576 TI - Development of functional tolerance to ethanol in rhesus monkeys (Macaca mulatta). PMID- 4204577 TI - Separation of photosynthetic systems I and II. PMID- 4204578 TI - 7S immunoglobulin M (IgM) from serum purified by anti-mu-chain immunoadsorbent: comparison of the reassociation properties of 7S IgM and various 19S IgM subunits. PMID- 4204579 TI - Low-molecular-weight antibody in rabbit urine: identity with the Fab immunoglobulin fragment. PMID- 4204580 TI - Studies on viral hepatitis and hepatitis B (Australia) antigen. PMID- 4204581 TI - Ecto-enzyme of granulocytes: 5'-nucleotidase. AB - The 5'-nucleotidase of guinea pig polymorphonuclear leukocytes is localized exclusively on the plasma membrane of intact cells. The active site of this enzyme faces the external medium, not the cytoplasm. PMID- 4204582 TI - Synthesis and expression of surface antigens during the cell cycle. PMID- 4204583 TI - The high incidence of anti-HL-A antibodies in anti-D typing reagents. Illustrated by a case of Matuhasi-Ogata phenomenon mimicking a "D with anti-D" situation. PMID- 4204584 TI - The influence of dialysis in 2-mercaptoethanol reduction of erythrocyte antibodies. PMID- 4204585 TI - Pseudomonas septicemia in neutropenic dogs. I. Treatment with granulocyte transfusions. PMID- 4204586 TI - Hepatitis carriers among soldiers who have returned from Vietnam. Australia antigen studies. PMID- 4204587 TI - Evaluation of the use of albumin controls in Rh phenotyping. PMID- 4204588 TI - B and T cell markers in human proliferative blood diseases and primary immunodeficiencies, with special reference to membrane bound immunoglobulins. PMID- 4204589 TI - [Pathobiology, clinical aspects and therapy of achalasia of esophagus]. PMID- 4204590 TI - Variant angina pectoris caused by coronary artery spasm. PMID- 4204591 TI - Juvenile xanthogranuloma diagnosed by paracentesis. PMID- 4204592 TI - Ocular toxicity from ethambutol. PMID- 4204594 TI - Changing methods in the treatment of severe pancreatitis. PMID- 4204593 TI - Use of chemically defined diets in the management of patients with high output gastrointestinal cutaneous fistulas. PMID- 4204595 TI - Further studies on nicotine-induced alterations in histamine metabolism in the rat. PMID- 4204596 TI - Tonsillectomies: in dollars and cents. AB - Over the last quarter of a century, much controversy has been generated on the indications for tonsillectomy and adenoidectomy. The economic aspects of this operation have received comparatively little attention. The rate per 10,000 children 0 to 19 years of age for the whole province of Ontario for the year 1971 was 174 and ranged from a high of 307 in one county to a low of 59 in another. The total cost of these operations to the health insurance plan was 11.4 million dollars. National studies on the indications for these operations, their benefits and hazards are urgently required. PMID- 4204597 TI - Metabolic studies on polychlorinated biphenyls. II. Metabolic fate of 2,4,3',4' tetrachlorobiphenyl in rats. PMID- 4204598 TI - Metabolic studies on polychlorinated biphenyls. 3. Complete structure and acute toxicity of the metabolites of 2,4,3',4'-tetrachlorobiphenyl. PMID- 4204599 TI - Congenital pseudarthrosis of the radius. PMID- 4204600 TI - Letter: The cell division of the pigment epithelium in the repairing retina after photocoagulation. PMID- 4204601 TI - Immune response of pathogen-free mice inoculated intranasally with Mycoplasma pulmonis. PMID- 4204602 TI - Human J-chain: isolation and molecular weight studies. PMID- 4204603 TI - The association of J chain with the Fc region of human IgM. PMID- 4204604 TI - Isolation and characterization of the proenzyme form of the C1s subunit of the first complement component. PMID- 4204606 TI - Antigenicity of reduced and alkylated Australia antigen. PMID- 4204605 TI - Membrane receptors and in vitro responsiveness of lymphocytes in human immunodeficiency. PMID- 4204607 TI - Immunoglobulins in CSF in multiple sclerosis and other neurological disorders. PMID- 4204608 TI - [Determination of glomerular filtration rate with 51 Cr-EDTA: evaluation of the method utilizing a single intravenous injection and the blood clearance curves]. PMID- 4204609 TI - [Renal artery hypertension complicating neurofibromatosis]. PMID- 4204610 TI - [New findings on the functional structure of the region of the angle of the chamber and its changes after glaucoma surgery (author's transl)]. PMID- 4204611 TI - [The quality of eye drops prepared according to prescription (author's transl)]. PMID- 4204613 TI - [Proceedings: Round-table discussion on the topic: "Role of laboratory in preoperative preparation and postoperative control of the surgical patient"]. PMID- 4204612 TI - [Proceedings: Intensive care of patients with severe head injury in the general hospital (author's transl)]. PMID- 4204614 TI - Letter: Intal in childhood asthma. PMID- 4204615 TI - [Extraction and characterization of phenoloxidase-activity from tannin containing leaves (author's transl)]. PMID- 4204616 TI - The baboon. Clinical chemistry. PMID- 4204617 TI - The baboon. Hematology. PMID- 4204618 TI - The baboon. Parasitology. PMID- 4204619 TI - [Lysosomes, membranes, aging processes and drugs]. PMID- 4204620 TI - Immunosuppressive activity of the Pseudomonas aeruginosa endotoxin on a lysozyme anti-lysozyme system. PMID- 4204621 TI - Phenoloxidase system in wild and mutant adults of drosophila melanogaster. I. Activation and activity of mono- and diphenoloxidases. PMID- 4204622 TI - Ribonucleoprotein particles containing mRNA and pre-mRNA. PMID- 4204623 TI - Non-ribosomal polypeptide synthesis. PMID- 4204624 TI - Specific secretory protein of the female genital tract. PMID- 4204625 TI - Protein synthesis in mammary gland. PMID- 4204626 TI - Monoamine-containing cell bodies in the squirrel monkey brain. PMID- 4204627 TI - Osteoradionecrosis of the jaw. PMID- 4204628 TI - [Ricketsia prowazekii with hyperresistance to levomycetin and their properties]. PMID- 4204629 TI - Effect of mirex on the activities of various rat hepatic mixed-function oxidases. PMID- 4204630 TI - The influence of oxygen on the fluorescence of lipoxygenase. PMID- 4204631 TI - The conversion of bisnorbiotin and bisnordethiobiotin to biotin and dethiobiotin, respectively, by microorganisms. PMID- 4204632 TI - Immunochemistry of sperm-whale myoglobin. XVII. Conformation and immunochemistry of derivatives modified at lysines 98, 140 and 145 by reaction with 3,3 tetramethyleneglutaric anhydride. PMID- 4204634 TI - Conformational change of bovine serum albumin induced by O.IO m Tris-EDTA-boric acid buffer at pH9. PMID- 4204633 TI - Heat denaturation of bovine serum albumin in alkaline pH region. PMID- 4204635 TI - Vitamin B12 binding proteins in monkey serum and red cells. PMID- 4204636 TI - Snake venom toxins. The amino acid sequences of two toxins from Dendroaspis jamesoni kaimosae (Jameson's mamba) venom. PMID- 4204637 TI - [Lymphocyte membranes in the freeze-etching picture]. PMID- 4204638 TI - Compensatory renal hypertrophy in eviscerated rats. PMID- 4204639 TI - Olfactory recognition in the infant squirrel monkey. PMID- 4204640 TI - Growth and behavior of surrogate-reared squirrel monkeys. PMID- 4204641 TI - Non-specific immunologic precipitin reactions in alpha-fetoprotein determination. Analysis of two cases. PMID- 4204642 TI - [Incidence of diarrhea and antibiotic therapy in cynomolgus monkeys imported for medical use (author's transl)]. PMID- 4204643 TI - [Metabolism of triiodothyronine and thyroxine in a case of thyroxine binding globulin deficiency with hypothyroidism]. PMID- 4204644 TI - [Live Bac. cereus in some food products]. PMID- 4204645 TI - [Some experimental data on the effect of DDT and Sevin on the development of cholesterol arteriosclerosis]. PMID- 4204646 TI - Problems in the definition of ill health. PMID- 4204647 TI - Perinatal immunity in calves. PMID- 4204648 TI - A simple method of preparation of gastrointestinal tract tissues for scanning electron microscopy. PMID- 4204649 TI - The stability of second-order conditioned limb responses established in hens with cerebral electrical stimuli. PMID- 4204650 TI - Rheumatic fever presenting as an acute abdomen. PMID- 4204651 TI - Alterations of serum opsonins in patients with severe thermal injury. PMID- 4204652 TI - Erythroblast ferritin: synthesis, structure, and function in developing erythroid cells. PMID- 4204653 TI - The kinetics of 67gallium incorporation into inflammatory lesions: experimental and clinical studies. PMID- 4204654 TI - A new look at mumps encephalitis: inclusion bodies and cytopathic effects. PMID- 4204656 TI - Diarrhea toxin obtained from a waterbloom-producing species, Microcystis aeruginosA Kutzing. AB - A diarrhea-producing toxin from a blue-green alga, Microcystis aeruginosa Kutzing, was obtained from standing laboratory cultures. The non-dialyzable fraction of the lysate from whole cells produced fluid accumulation in the ligated small intestinal loops in guinea pigs. PMID- 4204655 TI - [Endogenous inhibitors of fibrinolytic activity in liver cirrhosis (author's transl)]. PMID- 4204657 TI - [Clinical significance of pathogenic nonspecific microflora in restricted pulmonary tuberculosis]. PMID- 4204658 TI - [Use of aerosol inhalations of hypertonic solution of sodium chloride for the detection of Mycobacterium tuberculosis]. PMID- 4204659 TI - Teratogenic effects of aldrin, dieldrin, and endrin in hamsters and mice. PMID- 4204661 TI - Critical point drying of protozoan cells and other biological specimens for scanning electron microscopy: apparatus and methods of specimen preparation. PMID- 4204660 TI - Teratogenic effects of ochratoxin A in mice. PMID- 4204662 TI - [Treatment of esophageal diverticula]. PMID- 4204664 TI - [Retention and primary distribution of a microbial aerosol in the organism (review of the literature)]. PMID- 4204665 TI - The variant form of angina: diagnostic and therapeutic implications. PMID- 4204663 TI - [Meningococcal antigens and methods for their isolation (review of the literature)]. PMID- 4204666 TI - [Acute Chagas' disease in children at Cochabamba (Bolivia)]. PMID- 4204667 TI - Animal reservoirs and Gambian trypanosomiasis. PMID- 4204668 TI - Nephrogenic diabetes insipidus secondary to declomycin. PMID- 4204669 TI - Steady-state enzyme kinetics with high-affinity substrates or inhibitors. A statistical treatment of dose-response curves. AB - A statistical treatment of steady-state enzyme kinetic measurements is described that allows for depletion of free substrate or free inhibitor concentrations owing to significant binding to the enzyme. V(max.), K(m) or K(i), enzyme concentration, the concentration of substrate or inhibitor required for a half maximal effect and standard errors of these parameters can be calculated from dose-response measurements; the concentration of each component of the system may be estimated also. The statistically best values of the parameters are used to convert dose-response curves into convenient linear forms. The method is applied to dose-response measurements of hydroxyquinoline N-oxide inhibition of bacterial respiration and aminopterin inhibition of dihydrofolate reductase. Two FORTRAN programs for this method have been deposited as Supplementary Publication no. SUP 50019 at the National Lending Library for Science and Technology, Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained on the terms indicated in Biochem. J. (1973) 131, 5. PMID- 4204671 TI - Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia. PMID- 4204670 TI - Gastrointestinal problems in the old. II. PMID- 4204672 TI - Specific lymphocyte stimulation by purified, heat-inactivated hepatitis-B antigen. AB - The ability of purified, heat-inactivated hepatitis-B antigen (HBAg) to stimulate sensitized lymphocytes in vitro was investigated with the lymphocyte stimulation test on lymphocytes from three groups of individuals. Stimulation was minimal in the lymphocytes of two out of 15 normal controls, whereas lymphocytes from nine out of 12 patients who had recovered from hepatitis B showed stimulation, as did lymphocytes from five out of 12 laboratory technicians who had been regularly exposed to HBAg but who had no history of hepatitis or signs of it in the previous two years. No differences were observed in the responses to phytohaemagglutinin of lymphocytes from persons in the three groups. HBAg and HBAg inactivated by heat were shown in immunodiffusion to be immunologically identical. Inactivated HBAg stimulated antibody production in guinea-pigs. These findings suggest that not only humoral but also cell-mediated immunity might be induced by vaccination with purified, heat-inactivated HBAg. PMID- 4204673 TI - Use of Tenckhoff catheter for peritoneal dialysis in terminal renal failure. AB - Over a period of 33 months a total of 2,146 peritoneal dialyses were carried out by means of indwelling Tenckhoff catheters in 65 patients suffering from terminal renal failure. The patients were maintained on peritoneal dialysis for periods varying from two weeks to 13 months. Treatment over long periods was possible in only a few cases. Infection and clotting, which tended to limit the functional life of the catheters, was reduced by rigid asepsis and by adding heparin to the dialysate. The Tenckhoff catheter was found to be valuable for peritoneal dialysis as a short-term measure, especially in patients in whom haemodialysis was not immediately feasible, in borderline cases when kidney function was not too seriously impaired, and as an alternative to haemodialysis when that was interrupted by complications. PMID- 4204675 TI - Cancer statistics, 1974--worldwide epidemiology. PMID- 4204676 TI - Systematic head and neck examination. PMID- 4204674 TI - Detection of cervical neoplasia: reducing the risk of error. PMID- 4204677 TI - Emotional crises and cancer. PMID- 4204678 TI - Cancer mortality in Blacks. PMID- 4204680 TI - [Letter: Prevention of hemophilia complications]. PMID- 4204679 TI - Classics in oncology. Matthew Baillie (1761-1823). PMID- 4204681 TI - Sulfuric acid for the cleanup of animal tissues for analysis of acid-stable chlorinated hydrocarbon residues. PMID- 4204682 TI - Removing substances from blood by affinity chromatography. I. Removing bilirubin and other albumin-bound substances from plasma and blood with albumin-conjugated agarose beads. AB - Substances such as bilirubin that bind tightly to plasma proteins cannot readily be removed from blood. We describe here the use of affinity chromatography as a new approach to the removal of proteinbound metabolites and toxins from blood. Agarose beads were coupled via cyanogen bromide to human serum albumin so as to contain 30-50 mg of albumin/g wet wt. Such beads, when exposed to plasma from a patient with congenital nonhemolytic jaundice labeled with [(14)C]-bilirubin, bound more than 150 mug bilirubin/g of beads. The binding was saturable, concentration-dependent, relatively independent of flow rate, and reversible by elution with plasma, albumin, or 50% (vol/vol) ethanol. The beads could be repeatedly reused without loss of efficiency after ethanol elution and long storage in the cold. Salicylate, cortisol, and taurocholate, which bind weakly to albumin, were retarded by the beads but eluted with neutral buffer. Thyroxine, taurolithocholate, chenodeoxycholate, and digitoxin bound tightly but were eluted with 50% ethanol. Digoxin did not bind at all. When whole blood was passed over agarose-albumin beads, bilirubin was removed, calcium and magnesium fell slightly, but red cells, white cells, platelets, clotting factors, and a variety of electrolytes and proteins were substantially unchanged. Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits. Furthermore, it may be possible to make useful adsorbents by attaching other proteins to agarose or other polymer beads. PMID- 4204683 TI - Isolation of a novel glycoprotein from the urine of a patient with chronic myelocytic leukemia. AB - Patient B. J. with chronic myelocytic leukemia excreted 0.5-1.1 g protein per day in the urine. Gel filtration on Sephadex G-75 showed about one-third of this protein to be in molecular weight range 20,000-40,000 (fraction BJC). BJC, prepared from 9 liters of urine by gel filtration, was chromatographed on carboxymethylcellulose. Two proteins were eluted from the resin in pure form (as shown by zone and immunoelectrophoresis) in yields representing 8 and 3 mg/liter of urine: BJC1 and BJC2. Their amino acid compositions were identical. BJC1 contained 61% carbohydrate (33% hexose, 11% sialic acid, 13% glucosamine, 5% galactosamine). BJC2 contained one-fourth to one-half as much of each carbohydrate. Molecular weight of BJC1 was estimated at 29,000 by gel filtration. Neither glycoprotein reacted with rabbit antiserum to normal human serum.Antiserum to BJC1 was made in the rabbit. Immunoelectrophoresis with this antiserum showed a faint precipitin line, corresponding in mobility to BJC1, in normal human plasma, and a stronger line in most leukemic plasmas. By immunodiffusion, BJC1 was not detectable in normal human urine, but a positive reaction occurred in the following conditions: leukemia, 64-72%; other types of disseminated neoplastic disease, 36-78%; regional ileitis, 45%; ulcerative colitis, 38%; tuberculosis, 33%; during the 1st wk after major surgery, 33%.BJC2 was found in the urine by immunoelectrophoresis in 10% of patients with neoplastic disease and was not observed in urine of other patients or in human plasma. Amino acid composition, carbohydrate content, and antigenic specificity indicate BJC1 is a previously unrecognized member of the system of normal human plasma glycoproteins. Like certain other glycoproteins, its plasma concentration frequently increases in patients with neoplastic disease, chronic inflammatory disease, or tuberculosis and after surgery. Because molecular weight is 29,000, increased plasma concentration readily causes its appearance in the urine. PMID- 4204684 TI - Design and evaluation by nitrogen balance and blood aminograms of an amino acid mixture for total parenteral nutrition of adults with gastrointestinal disease. AB - This study was undertaken to assess the efficacy of an amino acid mixture formulated for intravenous use from estimates of requirements for essential amino acids of human adults, and from data previously derived from a study using casein hydrolysate as the amino acid source. This mixture contained 39.4% essential amino acids, with glycine, alanine, arginine, histidine, and proline selected to supply the nonessential nitrogen. Nitrogen balance and blood aminograms were measured in six adult patients with gastrointestinal disease, fed intravenously for 1 wk at each of three levels of amino acid intake, while all other nutrients were constant and adequate in relation to body weight. Four of the patients were then fed 1.0 g/kg of egg or meat protein orally for 1 wk at the end of the 3 wk study, while all nutrients other than the amino acids were fed intravenously. Average nitrogen balances of -0.8, 0.5, and 2.2 g/day were observed when the amounts of amino acids infused were 0.25, 0.5, and 1.0 g/kg, respectively. Fasting levels of threonine, glycine, cystine, methionine, isoleucine, tryptophan, and arginine, but not of the other amino acids, increased with the increment in input, although the levels were generally lower than normal. The increase in blood concentration observed during infusion was similar for each of the essential amino acids, indicating that the supply of each of the amino acids was much better balanced for utilization than casein hydrolysate. However the blood aminograms did suggest that some changes in composition of the mixture for the malnourished adult were desirable, such that the amino acid mixture resembled that needed by the normal growing child. Nitrogen balance in the four patients fed orally with high-quality protein averaged 2.0 g/day, showing that an amino acid mixture given intravenously, provided it is well-balanced, can be utilized as efficiently as protein given orally. It is concluded that the prediction of oral requirements for amino acids should be combined with observations on changes in blood aminograms during infusion over a range of amino acid input in the development of amino acid mixtures for intravenous feeding. PMID- 4204685 TI - Three-dimensional structures of giant mitochondria, dictyosomes and "concentric lamellar bodies" formed during the cell cycle of Euglena gracilis (Z) in synchronous culture. PMID- 4204686 TI - Fine structure of the newt parathyroid gland after EDTA administration: mechanism of formation and extrusion of secretory granules. PMID- 4204687 TI - Letter: Crystal-like structure in the sporulating cells of Bacillus subtilis 168. PMID- 4204688 TI - Thyroxine-binding proteins in sheep serum. PMID- 4204689 TI - Effect of thyroidectomy on the concentration of plasma thyroxine-binding proteins in sheep. PMID- 4204690 TI - Evaluation of nitroglycerin ointment. PMID- 4204691 TI - The simultaneous effect of protein-calorie malnutrition on weight and height velocity. PMID- 4204692 TI - Activation of a latent measles virus infection in hamster cells. AB - The characteristics of infectious measles virus released from latently infected hamster embryo fibroblast cells are described. Low levels of virus were released spontaneously when the cultures were incubated at 37 C; this phenomenon was observed 19 passages after the cells had been exposed to the virus and has continued through cell passage 45. The virus yield could be significantly increased by cocultivation of the hamster cells with BSC-1 cells or incubation of the latently infected cells at 33.5 C rather than at 37 C. Measles virus released after cocultivation demonstrated increased cytopathology in cell culture and reduced temperature sensitivity when compared to the virus released at 33.5 C. After cell passage 45, there was an increase in spontaneous release of virus. However, the viruses recovered by cocultivation or temperature release after cell passage 45 were nearly identical. These observations suggest a possible mechanism for measles virus activation in cells latently infected with this virus. PMID- 4204693 TI - Minicells of Bacillus subtilis: a new bacteriophage-blocking agent. AB - Bacteriophage SP01, SP17, and phi29 rapidly absorb irreversibly to minicells of Bacillus subtilis but do not produce a lytic cycle in minicells. PMID- 4204694 TI - Increased nerve-growth-stimulating activity in disseminated neurofibromatosis. PMID- 4204695 TI - Editorial: Nerve growth in neurofibromatosis. PMID- 4204696 TI - Letter: Enhancement of enzymatic activity in Fabry's disease. PMID- 4204698 TI - Letter: Cost of health services in Sweden and England. PMID- 4204697 TI - Letter: Priapism after phenoxybenzamine in a patient with Fabry's disease. PMID- 4204699 TI - Endotoxic shock. PMID- 4204701 TI - Preoperative megavoltage radiotherapy for advanced carcinoma of the rectum. PMID- 4204700 TI - Endocavity irradiation of early rectal cancers for cure: a series of 123 cases. PMID- 4204702 TI - [Immunity to diphtheria in adult men]. PMID- 4204703 TI - [Cutaneous symptoms of monoclonal dysglobulinemia]. PMID- 4204704 TI - [Diagnosis and treatment of Waldenstrom's macroglobulinemia]. PMID- 4204705 TI - [Radiation reaction of the lung in various fractionization of telegammatherapy based on clinical and animal-experiment studies]. PMID- 4204706 TI - Postgraduate education and training in public health. Report a WHO Expert Committee. PMID- 4204707 TI - Environmental and health monitoring in occupational health. Report of a WHO Expert Committee. PMID- 4204708 TI - Bioavailability of drugs: principles and problems. Report of a WHO Scientific Group. PMID- 4204709 TI - Malaria control in countries where time-limited eradication is impracticable at present. Report of a WHO Interregional Conference. PMID- 4204710 TI - [Relation of rehabilitation to genetics and teratology in ophthalmology]. PMID- 4204711 TI - Gold levels in serum during the treatment of rheumatoid arthritis with gold sodium thiomalate. PMID- 4204712 TI - Protein selectivity in the assessment of patients with proteinuria. PMID- 4204713 TI - Aetiological factors in ovine posthitis. PMID- 4204714 TI - Degradation of hyaluronic acid by baboon sex-skin tissue. PMID- 4204715 TI - Effect of sulfonylureas on the secretion of pancreatic immunoreactive glucagon and enteric glucagon-like immunoreactivity. PMID- 4204716 TI - A comparative evaluation of the ultrastructural changes following induced cerebral infarction in the squirrel monkey and baboon. PMID- 4204717 TI - Occurrence of 2-amino-2-deoxy-hexuronic acids as constituents of Vibrio parahaemolyticus K15 antigen. PMID- 4204718 TI - Biosynthesis of the crystal protein of Bacillus thuringiensis var. tolworth. 1. Kinetics of formation of the polypeptide components of the crystal protein in vivo. PMID- 4204719 TI - Biosynthesis of the crystal protein of Bacillus thuringiensis var. tolworth. 2. On the relation of transcriptional and translational events in the growth cycle. PMID- 4204720 TI - Purification and properties of an iodide peroxidase from submaxillary gland of goat. PMID- 4204721 TI - Evaluation of alclofenac treatment regimes in man. PMID- 4204722 TI - Virulence of multidrugresistant Mycobacterium tuberculosis. PMID- 4204723 TI - [Language evolution]. PMID- 4204724 TI - General and specific effects of modifiers of mutant expression. PMID- 4204725 TI - [Pharmacogenetics: variability of drug effects and metabolic reactions]. PMID- 4204726 TI - Growth hormone secretion in protein-calorie malnutrition. PMID- 4204727 TI - Response of rhesus monkeys to LRH throughout the ovarian cycle. PMID- 4204728 TI - Characterization of a human acute phase protein found in association with rubella virus infection. AB - A precipitating antigen, rho, was first detected in the blood of persons with rubella and in rubella virus-infected cell culture fluids (1). Partially purified antigens from both sources were examined and shown to have similar properties, although antigen from serum sedimented more heterogeneously, with estimated coefficients from 15 to 21 S, while that from culture fluids sedimented in the 11 14 S region. In each case, antigen was located in the beta-1 zone after electrophoresis in agarose, and at a density of 1.305 g/ml after centrifugation in CsCl. Stability characteristics were typical of protein antigens. Immunofluorescent microscopy revealed that rubella virus induced the appearance of rho antigen scattered throughout the cytoplasm of infected cells. When cells containing antigen were exposed for 24 h to 5 microg/ml actinomycin D rho was no longer detectable, indicating the probable cellular origin of the antigen. Also, titers in medium of infected cultures showed a reduction after actinomycin treatment, but levels of the virus-specified antigen, iota, were relatively unaffected. Rho appears to be a protein common to man and many animals. In vitro, it was induced by rubella virus and by adenovirus. In vivo, rho titers were shown to be elevated after rubella virus infection and, to a lesser extent, after infection with certain other viruses. High titers were also demonstrated in women late in pregnancy and in patients with rheumatoid arthritis. In man and the chimpanzee, the appearance and decline of rho in the blood after rubella virus infection were temporally similar to the patterns of CRP, although rho seemed to be a more sensitive indicator of infection. The data presented indicate that rho is a newly recognized acute phase protein inducible by certain virus infections and by other unidentified stimuli present prominently in pregnancy and rheumatoid arthritis. PMID- 4204729 TI - Localization of free and bound secretory component in human intestinal epithelial cells. A model for the assembly of secretory IgA. AB - Antibody reagents were made specific for each of the two forms of human SC, FSC and BSC, which is an integral part of the sIgA molecule. With the fluorescent antibody method the cytological and histological localization of FSC, BSC, and alpha-chains has been studied in various human mucous membranes. SC was present in columnar epithelial cells of the intestines and in the cells of serous acini of bronchial and salivary glands. In contrast, SC was not found in intestinal goblet cells or cells of mucous acini of bronchial and salivary glands. In the columnar epithelial cells of the small and large bowel, FSC was present most prominently in the Golgi zone, and much less prominently in the apical cytoplasm. On the other hand, BSC and alpha-chains were located only in the apical cytoplasm in an overlapping manner. The results favor a model in which sIgA is assembled inside epithelial cells from SC, which was synthesized in the same cell, and IgA, which entered the epithelial cell after synthesis in and secretion by a plasma cell. PMID- 4204730 TI - New, third class of amyloid fibril protein. AB - An unusual protein AR was isolated from the amyloid fibril preparation derived from a patient with primary amyloidosis. Protein AR was unique in its antigenicity, and revealed no structural identity with any known amyloid proteins or with immunoglobulin chains or fragments. Thus a new third class of amyloid fibril proteins besides the immunoglobulin light-chain variable region fragments and the nonimmunoglobulin protein AS, has been characterized. A component antigenically related to protein AR was found in the serum of the patient. PMID- 4204731 TI - Evaluation of thyrotropin-releasing hormone as a potential antidepressant agent in the conscious dog. PMID- 4204732 TI - Dental defects in hamsters infected with minute virus of mice. PMID- 4204733 TI - Dental pulp regeneration aided by blood and blood substitutes after experimentally induced periapical infection. PMID- 4204734 TI - Analysis of histologic criteria commonly used in pulp studies. PMID- 4204735 TI - [New ultrastructural studies on the acute chagasic myocarditis in the mouse (author's transl)]. PMID- 4204736 TI - [Hemograft rejection in the toad Bufo marinus (author's transl)]. PMID- 4204737 TI - [Use of mathematical methods in planning an experiment to choose the optimum medium for the synthesis of inosine by a culture of Bacillus subtilis gene-265]. PMID- 4204738 TI - [Growth of Tetrahymena pyriformis W on feed products of microbial origin]. PMID- 4204739 TI - Antigenicity and stilbamidine resistance in Trypanosoma brucei rhodesiense. PMID- 4204740 TI - Letter: Serology and antimicrobial sensitivity of meningococci isolated in Uganda. PMID- 4204741 TI - Enzyme variants in primate malaria parasites. PMID- 4204742 TI - Letter: Acquired resistance to Schistosoma haematobium in the baboon (Papio anubis). PMID- 4204743 TI - Letter: Identification of guinea-worm species. PMID- 4204744 TI - Cytotoxic substances in sera from P. knowlesi-infected rhesus monkeys. PMID- 4204745 TI - 6-Phosphogluconate dehydrogenase activity in malaria-infected erythrocytes. PMID- 4204746 TI - Eperythrozoon and Haemobartonella in primates. PMID- 4204747 TI - Acquired resistance to Schistosoma haematobium in the baboon. PMID- 4204748 TI - Malaria parasites in Presbytis aygula. New host record of Hepatocystis semnopitheci. PMID- 4204749 TI - Malaria parasites in Callosciurus nigrovittatus. PMID- 4204750 TI - Polychromophilus species in insectivorous bats. PMID- 4204751 TI - Hymenopteran egg-parasite of triatomine bugs. PMID- 4204752 TI - Malaria parasites of domestic fowl in Sabah. PMID- 4204754 TI - Two types of schizonts of Hepatocystis sp., a parasite of insectivorous bats in the Congo-Brazzaville. PMID- 4204753 TI - A multi-species malaria antigen for use in the indirect fluorescent antibody test. PMID- 4204755 TI - Chemotherapy for bladder cancer. PMID- 4204756 TI - Vesicoureteral reflux in adults. A twelve-year study of 122 patients. PMID- 4204757 TI - [The effect of maternal acquired immunity on the state of immunologic reactivity of the child during ontogenesis]. PMID- 4204758 TI - [The immune response and the process of marginotomy in lymphoid cells]. PMID- 4204759 TI - [Treatment of acute pancreatitis]. PMID- 4204760 TI - [Principles of steroid metabolism in pregnancies with Rh incompatibility (author's transl)]. PMID- 4204761 TI - [Time-dependent effect of an oral hypoglycemic agent upon serum glucose levels]. PMID- 4204762 TI - The effects of anesthetics on permeability to water of the inactivated toad bladder. PMID- 4204763 TI - [Pulmonary form of Waldenstrom's macroglobulinaemia (author's transl)]. PMID- 4204764 TI - Benzodiazepines in the treatment of epilepsy. A review. PMID- 4204765 TI - [Studies of the antigenic structure and biological properties of influenza B virus]. PMID- 4204766 TI - Health trends in three Asian countries--Ceylon, Malaysia and Singapore. PMID- 4204767 TI - Fine structure and function of ocular tissues. The ciliary body. PMID- 4204768 TI - Fine structure and function of ocular tissues. The vitreous. PMID- 4204769 TI - Fine structure and function of ocular tissues. Extraocular muscle. PMID- 4204770 TI - Specialized techniques in electron microscopy. PMID- 4204771 TI - An ergot alkaloid preparation (Hydergine) in the treatment of presenile brain atrophy (Alzheimer's disease): case report. PMID- 4204772 TI - Patient non-compliance within the context of seeking medical care for arthritis. PMID- 4204773 TI - About quantitative studies on the cerebral cortex. PMID- 4204774 TI - Long-term consequences of vestibular ablation by laser in a monkey. PMID- 4204775 TI - Hydergine for cerebral arteriosclerosis. PMID- 4204776 TI - Effects of scopolamine, amphetamine and benzodiazepines on conditioned suppression. PMID- 4204777 TI - The alteration of aversive thresholds with cholinergic and adrenergic agents. PMID- 4204778 TI - Proceedings: Penicillins: use of an animal model to predict bioavailability. PMID- 4204779 TI - Estimation of molecular weights of rat liver ribosomal proteins. PMID- 4204780 TI - The proteins of rapidly labelled polysomal mRNP of rat liver. PMID- 4204783 TI - Studies on serum antigens in carp. PMID- 4204781 TI - Study of the in-vitro sensitivity of meningococci and its implications in prophylaxis. PMID- 4204784 TI - Effects of genetic background on the competition between the asc and FM6 chromosomes of Drosophila melanogaster. PMID- 4204785 TI - Flavor aversions produced by contingent drug injection: relative effectiveness of apomorphine, emetine, and lithium. PMID- 4204786 TI - Preservation of 23-S chloroplast RNA as a single chain of nucleotides. PMID- 4204787 TI - Morphological plasticity of central adrenergic neurons. PMID- 4204788 TI - Neuronal alteration and reinnervation following axonal regeneration and sprouting in mammalian spinal cord. PMID- 4204789 TI - Anatomical and physiological correlates of plasticity in the central nervous system. PMID- 4204790 TI - Vitamin E in angina pectoris. AB - The claim that the symptoms of angina pectoris can usually be relieved by large doses of vitamin E has been reinvestigated by means of a randomized double-blind trial. The trial lasted nine weeks and consisted of two parts. One part was conducted as a regular double-blind trial involving 40 patients, half of whom received 3200 IU of vitamin E daily, while an equal number received an indistinguishable placebo. The second part of the trial involved 15 patients who were already taking a regular daily dose of between 400 and 2400 IU of vitamin E. Eight patients were assigned the same (or a larger) dose of vitamin E, while seven received placebo. Neither part of the trial yielded statistically convincing evidence that vitamin E is of value in the treatment of angina, but a small beneficial effect could not be ruled out. Taken in conjunction with the positive (but statistically non-significant) results obtained in the only other double-blind trial of vitamin E ever carried out on angina, and the encouraging results reported by other investigators in the treatment of intermittent claudication, it is suggested that further double-blind trials are justified. PMID- 4204791 TI - Estimation of serum and red cell folate by a simple radiometric technique. PMID- 4204792 TI - Computer reduction and analysis of neurophysiological data with special emphasis on evoked potential frequency analysis. PMID- 4204793 TI - Stereoscopic form disappearance in temporal lobe dysfunction. PMID- 4204794 TI - [Preparation, testing and use of a monospecific FITC-labelled antigonococcal serum]. PMID- 4204795 TI - [Adsorption of anti-Neisseria-Gonorrhoeae-FITC conjugates using lyophilized bovine bone marrow]. PMID- 4204796 TI - Ionophore A23187, calcium and contractility in frog eggs. PMID- 4204797 TI - Photoreactivation of excystment delay in Colpoda, induced by far ultraviolet radiation. PMID- 4204798 TI - What is a case of tuberculosis? The tuberculosis case spectrum in eight countries evaluated from 1235 case histories and roentgenograms. PMID- 4204799 TI - Isoniazid chemoprophylaxis of latent primary tuberculosis: in five trial centres in France from 1959 to 1969. PMID- 4204800 TI - Cellular changes in the lateral geniculate nucleus of infant monkeys after suture of the eyelids. PMID- 4204801 TI - The effect of different preparative methods on nuclear shape in the surface epithelium of the hamster ovary. PMID- 4204802 TI - Evaluation of an antiasthmatic agent cromolyn sodium (Aarane, Intal). PMID- 4204803 TI - Evaluation of post-episiorrhaphy pain: polyglycolic acid vs catgut sutures. PMID- 4204804 TI - Brenner tumor. PMID- 4204805 TI - Intubation: the simple approach to bleeding from the mesenteric small bowel. PMID- 4204806 TI - Epidemiology of heroin dependency among soldiers in Vietnam. PMID- 4204807 TI - Opiate addiction and military psychiatry to the end of World War II. PMID- 4204808 TI - Nursing practice in a medical research setting. PMID- 4204809 TI - Dental emergencies occurring among Navy-Marine personnel serving in Vietnam. PMID- 4204810 TI - Frequency of hepatitis-associated antigen among drug users in the Naval service. PMID- 4204811 TI - Optic chiasmatic arachnoiditis: improvement of rapidly failing vision following surgical lysis of chiasmatic adhesions and postoperative steroid therapy. PMID- 4204813 TI - Editorial: Communicating clinical research in nursing. PMID- 4204812 TI - Injuries to divers by marine animals: a simplified approach to recognition and management. PMID- 4204814 TI - Immunoprophylaxis of meningococcal infection. PMID- 4204815 TI - Psychiatric perspectives of the Vietnam veteran. PMID- 4204816 TI - Oral lymphogranuloma venereum and cervical lymphadenopathy. Case report. PMID- 4204817 TI - Transformation of an R-factor from Pseudomonas aeruginosa into Rhizobium trifolii. PMID- 4204818 TI - [Comparative investigations of penicillin V and propicillin with particular reference to tolerance (author's transl)]. PMID- 4204819 TI - [Serum uric acid levels and renal function (author's transl)]. PMID- 4204820 TI - [Myoglobin in the serum after myocardial infarction (author's transl)]. PMID- 4204822 TI - A comparison of direct and diluted sputum culture results. PMID- 4204821 TI - [Klinomycin, a new broad spectrum antibiotic (author's transl)]. PMID- 4204823 TI - [Some patterns of reproducation and survival of Rickettsia prowazekii in argasid ticks that have been experimentally infected]. PMID- 4204824 TI - ["In vivo" fixation of the lung using glutaraldehyde vapors. Attempt at measuring the thickness of the liquid film covering the alveoli]. PMID- 4204825 TI - [Respiratory insufficiency in chronic obstructive bronchopneumopathy and thromboembolitic disease]. PMID- 4204826 TI - [Multiple endothoracic localizations in Recklinghausen's neurofibromatosis (apropos of a case)]. PMID- 4204827 TI - Experimental allergic encephalomyelitis in hamsters. PMID- 4204828 TI - Species specificity in the TSH response to the administration of L-dopa. PMID- 4204829 TI - Pregnancy-associated serum antigens in the rat and mouse. PMID- 4204830 TI - The neural basis of visually guided behavior. PMID- 4204832 TI - Studies on reaction between thrombin and actin. PMID- 4204833 TI - Relationship of the localization of autosomal lethal mutations to their concentrations in natural populations of Drosophila melanogaster. PMID- 4204831 TI - Platelet aggregation by large molecules. PMID- 4204834 TI - Repair of UV-damaged DNA by competent and incompetent Bacillus subtilis cells. PMID- 4204835 TI - Urethral diverticulum in adult female. Clinical aspects, operative procedure, and pathology. PMID- 4204836 TI - Bladder diverticulectomy. With aid of inflated Foley balloon catheter. PMID- 4204837 TI - Psychophysical studies of monkey vision. I. Macaque luminosity and color vision tests. PMID- 4204838 TI - Psychophysical studies of monkey vision. II. Squirrel monkey wavelength and saturation discrimination. PMID- 4204839 TI - Psychophysical studies of monkey vision. 3. Spatial luminance contrast sensitivity tests of macaque and human observers. PMID- 4204840 TI - [The role of protozoa in human and animal brain pathology (review of the literature)]. PMID- 4204841 TI - Fate of exogenous DNA in Neisseria meningitidis. I. Preparation of 15N-donor DNA and its fate in transformation. PMID- 4204842 TI - Fate of exogenous DNA in Neisseria meningitidis. 2. Influence of acriflavin and ethidium bromide and significance of genetic competence on the fate of 15N DNA. PMID- 4204843 TI - Identification and quantitation of precipitins against Pseudomonas aeruginosa in patients with cystic fibrosis by means of crossed immunoelectrophoresis with intermediate gel. PMID- 4204844 TI - Wall teichoic acids in animal Staphylococcus aureus strains determined by precipitation. PMID- 4204845 TI - An easy way of improving the flatness of the radiation from a linear accelerator. PMID- 4204846 TI - Origin of radiation released serotonin in rabbits and mice. PMID- 4204847 TI - Plasma and leukocyte ascorbic acid levels in the elderly. PMID- 4204848 TI - Comparison of fibrin hydrolysates and crystalline amino acid solutions in parenteral nutrition. PMID- 4204849 TI - The matabolic fuel regulatory system: implications for protein-sparing therapies during caloric deprivation and disease. PMID- 4204850 TI - Nutritional hazards of food taboos and preferences in Mid-West Nigeria. PMID- 4204851 TI - Opponent processes as a model of neural organization. PMID- 4204852 TI - Experimental carbon monoxide encephalopathy in the primate I. Physiologic and metabolic aspects. PMID- 4204853 TI - Experimental carbon monoxide encephalopathy in the primate. II. Clinical aspects, neuropathology, and physiologic correlation. PMID- 4204854 TI - SSPE virus infections in suckling hamsters. Modification by intracerebral administration of poly I-C. PMID- 4204856 TI - Studies of a transplantable canine sarcoma. PMID- 4204855 TI - Pulmonary alveolar proteinosis and Nocardia brain abscess. Report of a case. PMID- 4204857 TI - Oncorna type virus particles in a tumor of a rhesus monkey. PMID- 4204859 TI - Effects of myelopoietic factors isolated from rat serum on murine myelogenous leukemia. PMID- 4204858 TI - Gross virus leukemia in the rat: kinetics of infection and immunity. PMID- 4204860 TI - [Effect of carbon-containing compounds on the chromatic characteristics of the blue-green alga Anacystis nidulans]. PMID- 4204861 TI - [Effect of Sevin on the Mongolian treecreeper]. PMID- 4204862 TI - [Effect of ethymisol on the quantitative composition of microelements and metal proteins in fetal asphyxia]. PMID- 4204863 TI - [Sensitivity in vitro to antibiotics and chemotherapeutic agents in various hospital strains of Pseudomonas aeruginosa]. PMID- 4204864 TI - [Functional aspects of thyroid cells after lithium or rubidium activity in scanning microscopy. Infracellular cytochemistry using simultaneous microdiffraction in x rays]. PMID- 4204865 TI - [Absorption, distribution, and elimination of parahydroxypropiophenone in animals]. PMID- 4204866 TI - [Variations and principal functions of the corpus allatum during the reproductive cycle of the female Labidura riparia Pallas (Insecta, Dermaptera)]. PMID- 4204867 TI - [Development of the gonad in the juvenile stages of a pelagic copepode, Temora stylifera (Calanoidea, Temoridae)]. PMID- 4204868 TI - [Is the polymorphism of the HL-A system maintained by a disadvantage of the homozygotes?]. PMID- 4204869 TI - [Average temperature of the human skin as a function of activity and environment]. PMID- 4204870 TI - [Influence of growth on the repair of radiation lesions responsible for the "little colony" cytoplasmic mutation in yeast]. PMID- 4204871 TI - [Demonstration of oligosaccharidosuria associated with various meliturias, and determination of the structure of the oligosaccharides excreted. Hypothesis concerning the origins of oligosaccharides in biological fluids]. PMID- 4204872 TI - [Action of alpha-methyldopa and its metabolites on the preferential liberation of newly synthesized 3H noradrenaline]. PMID- 4204873 TI - [Ultrastructure of the endopancreatic B cell. Insulinophoric granulogenesis and detection of pre- and intragranular zinc. Study using scanning microscopy and x ray microdiffraction]. PMID- 4204874 TI - [Biotransformation of parahydroxypropiophenone in animals]. PMID- 4204875 TI - [Evolution of the mortality rate after X-ray exposure during the larval stage of Bombyx mori]. PMID- 4204876 TI - [Isolation of Chlamydomonas reinhardtii mutants resistant to nalidixic acid]. PMID- 4204877 TI - [Triterpenes of Embelia concinna Bak. (Myrsinacea)]. PMID- 4204878 TI - [Phenylalanine ammoniac lyase activity of Nicotiana tabacum var. Xanthi n. c. and systemic infection by the tobacco mosaic virus]. PMID- 4204879 TI - [Immunologic properties of bacterial cell walls. Relation between the reticular structure and the immunostimulant activity of peptidoglycan in Bacillus megaterium]. PMID- 4204880 TI - The localization of "ordinary" sex-linked genes in section 20 of the polytene X chromosome of Drosophila melanogaster. PMID- 4204881 TI - Measurement of resistance to air flow in the nose in a trial with sodium cromoglycate (BP)solution in allergen-induced nasal stenosis. PMID- 4204882 TI - Serum IgE levels and the use of sodium cromoglycate (BP) in hay fever: a study of forty-six patients from a single general practice. PMID- 4204883 TI - Trace-element analysis in hair: an evaluation. PMID- 4204884 TI - Rapid ultramicro direct determination of erythrocyte lead concentration by atomic absorption spectrophotometry, with use of a graphite-tube furnace. PMID- 4204885 TI - [Cyclopia in a foal]. PMID- 4204886 TI - [The role of the accessory optic system in the regulation of natural sleep and wakefulness]. PMID- 4204887 TI - Notes on the ecology and behaviour of the Angola colobus (Colobus angolensis P. L. Sclater 1860) in N.E. Tanzania. PMID- 4204888 TI - Wrist mechanism and locomotor behavior of Dryopithecus (Proconsul) africanus. PMID- 4204889 TI - Interactions between adult female and infant howling monkeys (Alouatta palliata). PMID- 4204890 TI - Quality and intensity of sugar solutions as determinants of ingestion by the rhesus monkey (Macaca mulatta). PMID- 4204891 TI - Condensation of chromosomes during mitotic prophase. Whole mount electron microscopy of cerebral ganglion cells of Drosophila. PMID- 4204892 TI - Tricomplex, a new type of autosome complement in Drosophila melanogaster. PMID- 4204893 TI - Heritability of recombination frequency. Observations on statistical complications and report on small-scale tests in Drosophila. PMID- 4204894 TI - Genetic load in a repeatedly irradiated Drosophila melanogaster population. PMID- 4204895 TI - Localization of genes controlling radioresistance in Drosophila melanogaster. PMID- 4204896 TI - Characterization of a meiotic control gene affecting recombination in Drosophila melanogaster. PMID- 4204898 TI - Oxidation of catechol in plants. II. Enzymic conversion of catechol to diphenylenedioxide 2,3-quinone in the leaves of Tecoma stans L. PMID- 4204897 TI - The organization of chromosome fibrils in salivary-gland chromosomes of Drosophila melanogaster. Light microscopical observations of the effect of acetic acid. PMID- 4204899 TI - Purification and properties of hetero-beta-galactosidases from monkey liver and intestine. PMID- 4204900 TI - Neurofibromatosis--von Recklinghausen's disease in podiatric medicine. A review and report of two cases. PMID- 4204901 TI - Induction of psychological death in rhesus monkeys. PMID- 4204902 TI - Documentation of auxotrophic mutation in blue-green bacteria: characterization of a tryptophan auxotroph in Agmenellum quadruplicatum. AB - A tryptophan-requiring auxotroph of Agmenellum quadruplicatum strain BG1, a species of blue-green bacteria, was isolated by means of a nitrosoguanidine penicillin procedure. Its growth characteristics were determined, and the enzymological block was identified in the A activity of tryptophan synthetase. Starvation of the auxotroph for tryptophan resulted in the derepression of the synthesis of all five enzymes. The first four enzymes derepressed 2- to 3-fold, and tryptophan synthetase B derepressed 20-fold. In the parental prototroph, BG1, anthranilate synthetase was active in crude extracts with ammonia as the amino donor reactant, but not with glutamine. PMID- 4204903 TI - Nature of the elimination of the penicillinase plasmid from Staphylococcus aureus by surface-active agents. AB - Growth of Stapylococcus aureus in various ionic surface-active agents resulted in loss of the ability to produce penicillinase, whereas growth in nonionic surface active agents had no effect on penicillinase production. The curing effect of various alkyl sulfates was found to be dependent upon the chain length. Curing by surface-active agents could be inhibited by magnesium. Reciprocal transduction experiments showed that curing by a surface-active agent was a property of the plasmid, not of the bacterial strain in which the plasmic resides. PMID- 4204904 TI - Deoxyribonucleic acid distribution in Bacillus subtilis independent of cell elongation. AB - A temperature-sensitive DNA(-) mutant of Bacillus subtilis has been studied during the resumption of deoxyribonucleic acid (DNA) synthesis following a 45 to 30 C temperature shift. For several hours after return to 30 C, DNA synthesis proceeds although the cells fail to elongate appreciably. Autoradiographs of cell populations synthesizing DNA during the recovery period demonstrate that DNA can become distributed to previously unoccupied regions along the cell length. By varying the labeling regime, newly synthesized DNA as well as DNA present at the time of transfer from 45 to 30 C were followed independently. Measurements of the percent of cell length covered by grains ((3)H-thymine in DNA) demonstrate the progressive refilling of DNA-vacant cell regions by both newly synthesized and original DNA. These data indicate that cell surface growth is not an absolute requirement for segregation of bacterial DNA. PMID- 4204905 TI - Initiation of Bacillus subtilis ribonucleic acid polymerase on deoxyribonucleic acid from bacteriophages 2C, phi 29, T4, and lambda. AB - Ribonucleic acid (RNA) synthesis primed by bacteriophage T4 or lambda deoxyribonucleic acid (DNA) with Bacillus subtilis RNA polymerase is severely inhibited by high ionic strength. In contrast, RNA synthesis on B. subtilis bacteriophage 2C, SPO1, or phi29 DNA is only moderately affected under similar conditions. The basis of this inhibition lies in the inability of the enzyme to initiate RNA chains with adenosine triphosphate or guanosine triphosphate (ATP, GTP). Binding to templates and the rate of catalysis in high salt after initiation do not seem to be affected. Incorporation of gamma-(32)P-ATP and GTP under a variety of conditions suggests that the specificity of B. subtilis RNA polymerase is different from that of the Escherichia coli enzyme and that it recognizes few promoters on T4 and lambda DNA. Although B. subtilis RNA polymerase initiates RNA chains primarily with ATP or GTP, initiations with pyrimidines can occur on DNA molecules in which hydroxymethyluracil replaces thymine. RNA synthesis on denatured DNA does not seem to be inhibited by high ionic strength, and on native T4 or lambda DNA the inhibition of initiation at constant ionic strength is inversely but not linearly proportional to the ionic radii of cations used to stabilize bihelical DNA to denaturation. PMID- 4204906 TI - Comparative immunological and enzymatic study of the tryptophan synthetase beta 2 subunit in the Enterobacteriaceae. AB - The beta(2) subunits of tryptophan synthetase, formula alpha(2)beta(2), from Escherichia coli, Shigella dysenteriae, Enterobacter aerogenes, Salmonella typhimurium, and Serratia marcescens were compared by three criteria. (i) alphabeta association constants for the various beta(2) subunits and E. coli alpha subunit varied between 3.6 x 10(8)m(-1) for E. coli and 0.33 x 10(8)m(-1) for S. marcescens; values for the other organisms were intermediate. (ii) Antiserum neutralization of the beta(2) subunit enzyme activity using anti-E. coli beta(2) serum showed significant cross-reaction among the organisms (E. coli, 1.0; S. dysenteriae, 0.98; S. typhimurium, 0.67; E. aerogenes, 0.61; S. marcescens, 0.42). (iii) Quantitative microcomplement fixation showed E. coli beta(2) and S. marcescens beta(2) subunits to have an index of dissimilarity of 1.8 while the other organisms had intermediate indexes. Similar complement fixation data were obtained with antisera from separate rabbits and from first course and boost sera. These findings suggest that the general surface structure and the respective alpha subunit binding site of the beta(2) subunits from these Enterobacteriaceae have been strongly conserved. PMID- 4204908 TI - Division site regulation in a temperature-sensitive mutant of Bacillus subtilis. AB - Division site location was measured in Bacillus subtilis clones grown from spores at 30 and 45 C. Regulation of division location is lost in mutant 168ts-151 at 45 C. PMID- 4204907 TI - Genetically controlled removal of "spore photoproduct" from deoxyribonucleic acid of ultraviolet-irradiated Bacillus subtilis spores. AB - Previous genetic analysis indicated that at least two genes determine the ultraviolet (UV) sensitivity of Bacillus subtilis spores. The present study shows that these genes independently control two distinguishable processes for removing UV-induced spore photoproduct (5-thyminyl-5,6-dihydrothymine, or TDHT) from spore deoxyribonucleic acid. The first, is a spore repair mechanism by which TDHT is removed rapidly without appearing in acid-soluble form. This mechanism, which is demonstrated in both UV-resistant and excision-deficient strains, operates to a certain extent during germination without requiring vegetative growth. The second, demonstrated in a mutant which lacks the first mechanism, removes TDHT relatively slowly and only if germinated spores are allowed to develop toward vegetative cells. The latter mechanism appears identical to excision-resynthesis repair, since the mutation abolishing it renders the irradiated vegetative cells incapable of removing cyclobutane-type pyrimidine dimers. Blocking either one of these mechanisms only slightly affects the UV sensitivity of spores, but blocking both prevents TDHT removal and gives high UV sensitivity. PMID- 4204909 TI - Phenoloxidase activity in mycelia carrying modifier mutations that affect sporocarp development in Schizophyllum commune. AB - Phenoloxidase activity was studied in mycelia carrying mutations that affect sporocarp formation. The results suggest that phenoloxidase activity may be essential to, but is not sufficient for, the fruiting response in Schizophyllum. PMID- 4204910 TI - Time course of purine nucleoside phosphorylase occurrence in sporulation of Bacillus cereus. AB - Purine nucleoside phosphorylase (EC 2.4.2.1) from Bacillus cereus T was examined at hourly intervals during growth and sporulation. The enzyme has maximal activity in extracts prepared from cells during stages I and II. The activity during exponential growth is only 6.6% of the maximum and that in free spores is only 3.3%. Conservation of the purine nucleoside phosphorylase during sporulation is apparent as shown by the gradual increase in heat resistance. PMID- 4204911 TI - Mapping of rod mutants of Bacillus subtilis. AB - Nine class A salt-dependent rod mutants were mapped on the Bacillus subtilis genome by PBS1-mediated transduction. They are distributed into two small linkage groups designated rod B and rod C; mutations in rod B are over 80% cotransducible with pheA and different mutations in rod C are 12 to 21% cotransducible with hisA. It is established that neither rod B nor rod C is linked by transformation to the other identified rod mutations present in 168-ts-200B and 8332 glu(-). It is hypothesized that salt-dependent mutations are due to enzyme alterations which are corrected by high salt concentrations. PMID- 4204912 TI - Synthesis of pulcherriminic acid by Bacillus subtilis. AB - The pathway of pulcherriminic acid synthesis in Bacillus subtilis strains AM and AM-L11 (a leucine-requiring auxotroph) was investigated. Determinations of radioactivity in pulcherriminic acid synthesized by cells growing in media containing (14)C-labeled amino acids indicated that B. subtilis produced pulcherriminic acid from l-leucine. The organism utilized the carbon skeletons of two l-leucine molecules to synthesize one molecule of pulcherriminic acid. Similar results were obtained with starved cell suspensions. Growing cells formed significant amounts of pulcherriminic acid only in media including a carbohydrate such as starch. However, carbohydrate carbon was not required for the synthesis of pulcherriminic acid molecules. Data obtained with cell suspensions supported the hypothesis that cyclo-l-leucyl-l-leucyl is an intermediate in pulcherriminic acid biosynthesis and indicated that molecular oxygen is required for the conversion of cyclo-l-leucyl-l-leucyl to pulcherriminic acid. A pathway for the synthesis of pulcherrimin from l-leucine in B. subtilis is proposed. PMID- 4204914 TI - Perinatal tips. PMID- 4204913 TI - Isotopic study of control of the lysine biosynthetic pathway during sporulation of Bacillus cereus. AB - The extent of incorporation of aspartate into dipicolinic acid and into various amino compounds was determined in Bacillus cereus at various times before, during, and near the end of synthesis of dipicolinic acid. The purpose of this study was to gain further information on the in vivo control of the biosynthesis of amino acids derived from aspartate. Control of the lysine biosynthetic pathway was of particular interest with regard to sporulation, owing to the important role of diaminopimelate and dipicolinate in the structure of the spore. As synthesis of dipicolinate was initiated, incorporation of carbon derived from aspartate was funneled preferentially into this compound as compared with others of the aspartate group. Incorporation into lysine essentially stopped just before the synthesis of dipicolinate began. This is consistent with the previously observed disappearance at this time of diaminopimelic acid decarboxylase in cell free extracts. Synthesis of diaminopimelate continued during the time of synthesis of dipicolinate. The previous suggestion that diaminopimelate might exert negative control on one of the enzymes between dihydrodipicolinate and diaminopimelate is thus considered unlikely. The possibility is discussed that synthesis of dipicolinate is favored by an increase in the rate of synthesis of dihydrodipicolinate rather than by a block in its rate of utilization. PMID- 4204915 TI - Tropical sprue in South Vietnam. PMID- 4204916 TI - Shoulder girdle neuritis: a clinical and electrophysiological evaluation. PMID- 4204917 TI - Bridging a cultural gap for better patient care. PMID- 4204918 TI - An experiment in postgraduate medical education: an orientation program for residents in clinical research. PMID- 4204919 TI - Acute exertional rhabdomyolysis: a syndrome of increasing importance to the military physician. PMID- 4204920 TI - Case for diagnosis. PMID- 4204921 TI - Multiple intracranial arterial aneurysms: current thoughts about diagnosis and treatment. PMID- 4204922 TI - A fatal case of hexachlorophene poisoning. PMID- 4204923 TI - Drug induced intrahepatic cholestatic jaundice: case reports. PMID- 4204924 TI - Vesicoureteral reflux: a review. PMID- 4204925 TI - Editorial: The uniformed services medical school. PMID- 4204926 TI - Sitting on a basketball: how it feels to be a paraplegic. PMID- 4204927 TI - The dissociation between renal HCO3- reabsorption and H+ secretion in the skate, Raja erinacea. PMID- 4204928 TI - [Results of daily-oral therapy with ethambutol and isoniazid in tuberculosis (author's transl)]. PMID- 4204929 TI - Letter: The antimalarial activity of RC-12 against gametocytes and sporogony of Plasmodium cynomolgi. PMID- 4204930 TI - Letter: Circadian rhythm in the parasitaemia of the primate haemoflagellate, Trypanosoma minasense. PMID- 4204931 TI - [The effectiveness of surgical methods in focal epilepsy (West Berlin)]. PMID- 4204932 TI - [The significance of the interhemispheric asymmetry of evoked potentials to light in epilepsy]. PMID- 4204933 TI - [An analysis of interhemispheric asymmetry in the reciprocal reactions of the brain in epilepsy]. PMID- 4204934 TI - [The evoked potentials of epileptic patients]. PMID- 4204935 TI - [Clinico-electrophysiologic correlates in patients with focal epilepsy]. PMID- 4204936 TI - [Clinico-electromyographic characteristics of movement disorders during seizures in epileptic patients]. PMID- 4204937 TI - [The latent period of the motor reaction in focal epilepsy]. PMID- 4204938 TI - [The course and hemispheric lateralization of epileptogenic foci in epilepsy complicated by allergy]. PMID- 4204939 TI - [Partial and complete discontinuation of treatment in epilepsy]. PMID- 4204941 TI - Polycholorinated biphenyls. VI. 2,3,7,8-tetrachlorodibenzofuran, a critical byproduct in the synthesis of 2,2',4,4',5,5'-hexachlorobiphenyl by the Ullmann reaction. PMID- 4204940 TI - [The place of nitrazepam in the complex treatment of epilepsy]. PMID- 4204942 TI - [Detection of the Au antigen in the population of Cosenza region]. PMID- 4204943 TI - [Fixation with TAPO in ultrastructural study of bacterial cells. I. Cell wall of Bacillus cereus in ultra-thin sections]. PMID- 4204945 TI - [Effect of iron and other mineral elements on the biosynthesis of tetracycline]. PMID- 4204944 TI - Esophageal intramural diverticulosis: a clinical and pathological survey. PMID- 4204946 TI - [Tilorone as an interferon inducer]. PMID- 4204947 TI - [Determination of lysozyme in the tissues and organs of white mice]. PMID- 4204948 TI - [Effect of heparin on penicillin concentration in the blood in animals with experimental pneumonia]. PMID- 4204949 TI - [Action of the antibiotic beromycin on hematopoiesis in laboratory animals and its pharmacokinetics]. PMID- 4204950 TI - Inhibition of metabolism by hydrostatic pressure: what limits microbial growth? PMID- 4204951 TI - Glycyl-L-leucine hydrolase, a versatile 'master' dipeptidase from monkey small intestine. AB - 1. A highly active and electrophoretically homogeneous dipeptidase was purified from the soluble extracts of monkey small-intestinal mucosa. 2. By gel-filtration studies the molecular weight of the enzyme was found to be 107000. It is composed of two identical, subunits of molecular weight 54000. 3. A paper-chromatographic method of dipeptidase assay was developed to overcome some of the difficulties encountered in the generally used spectrophotometric procedure. By using this method, the K(m) and k(0) values of a few substrates were determined. 4. The substrate specificity of the enzyme was investigated in great detail with substrates of a wide range of possible structural types. The enzyme hydrolyses a very large proportion of the range of dipeptides tested. This enzyme, which exhibits such a wide range of action, has been termed the ;master' dipeptidase of the intestine. Glycylglycine, glycyl-l-proline, glycyl-l-histidine, l prolylglycine and some of the arginine- and aspartic acid-containing dipeptides were not substrates and are possibly hydrolysed by other peptidases. These results therefore suggest that in the intestine the number of dipeptidases is rather limited. 5. In the light of these findings, the implications on the role of dipeptidases in intestinal peptide transport are discussed. PMID- 4204952 TI - Purification and some properties of cytoplasmic aspartate aminotransferase from sheep liver. AB - 1. A procedure for the purification of the cytoplasmic isoenzyme of aspartate aminotransferase from sheep liver is described. 2. The purified isoenzyme shows a single component in the ultracentrifuge at pH7.6 and forms a single protein band on agar-gel electrophoresis at pH6.3 or 8.6, as well as when stained for protein or activity after polyacrylamide-gel or cellulose acetate electrophoresis at pH8.8. 3. Immunoelectrophoresis on agar gel yields only one precipitin arc associated with the protein band, with rabbit antiserum to the purified isoenzyme. By immunodiffusion, cross-reaction was detected between the cytoplasmic isoenzymes from sheep liver and pig heart, but not between the cytoplasmic and mitochondrial sheep liver isoenzymes. 4. The s(20,w) of the enzyme is 5.69S and the molecular weight determined by sedimentation equilibrium is 88900; 19313 molecules of oxaloacetate were formed/min per molecule of enzyme at pH7.4 and 25 degrees C. 5. The amino acid composition of the isoenzyme is presented. It has about 790 residues per molecule. 6. The holoenzyme has a maximum of absorption at 362nm at pH7.6 and 25 degrees C. 7. A value of 2.1 was found for the coenzyme/enzyme molar ratio. 8. The purified enzyme revealed two bands of activity on polyacrylamide-gel electrophoresis at pH7.4 and an extra, faster, band in some circumstances. These bands occurred even when dithiothreitol was present throughout the isolation procedure. 9. Three main bands were obtained by electrofocusing on polyacrylamide plates with pI values 5.75, 5.56 and 5.35. 10. Structural similarities with cytoplasmic isoenzymes from other organs are discussed. PMID- 4204953 TI - Purification and some properties of rabbit anti-ovalbumin. AB - Unlike previous reports that the ovalbumin-anti-ovalbumin complex did not dissociate completely in acid media, our results showed complete dissociation of the complex both in 1.2m-acetic acid, pH2.3, and in KCl-HCl, pH2.2, I 0.06. Thus Sephadex chromatography of the solution obtained by dissolving the antigen antibody precipitate in these media repeatedly gave two peaks corresponding to anti-ovalbumin and ovalbumin. Further, gel-diffusion and immunoelectrophoresis experiments showed that the phosphate groups of ovalbumin are not involved in the antigenic sites. The antibody thus purified was more easily precipitated than previous preparations. The molecular weight and Stokes radius of the antibody were calculated from its gel-filtration behaviour and were found to be 148000 and 4.8nm respectively. The molecular weight determined by sodium dodecyl sulphate polyacrylamide gel electrophoresis was essentially similar (about 0.7% lower). PMID- 4204955 TI - Use of affinity chromatography for the quantitative study of acceptor-ligand interactions: The lactose synthetase system. AB - From the effects of N-acetyl-d-glucosamine and d-glucose on the elution of the A protein of human lactose synthetase from a column of Sepharose-alpha-lactalbumin, values of 200m(-1) and 0.57m(-1) are deduced for the association constants describing the interaction between the enzyme and the respective monosaccharides. PMID- 4204954 TI - Polymerization of proteins with glutaraldehyde. Soluble molecular-weight markers. AB - Glutaraldehyde is well known for its ability to react with proteins and to produce insoluble cross-linked aggregates. In contrast with this situation, conditions are described here which yield covalently linked soluble protein oligomers. The procedure is applicable to a wide range of proteins, and by slight variation in the reaction conditions, soluble polymers in the molecular weight range 3x10(4)-2x10(7) were produced. The products are valuable as molecular weight markers, e.g. in sodium dodecyl sulphate-polyacrylamide-gel electrophoresis. The inherent similarities of these oligomers make them superior to commercial molecular-weight protein markers, which may have marked differences in composition and charge. PMID- 4204956 TI - [Chemical and physico-chemical properties of the exo-enterotoxin of Bacillus cereus]. PMID- 4204958 TI - [A comparative study of photooxidation of chlorophyll analogs in an aqueous solution of detergents]. PMID- 4204957 TI - [SH-groups and structural features of rat skeletal muscle glyceraldehyde-3 phosphate dehydrogenase]. PMID- 4204959 TI - The size of the Langerhans' islets in infants with severe jaundice of varying etiology. PMID- 4204960 TI - Effects of bilirubin loading of pregnant rats on hepatic UDP glucuronyltransferase activity in the offspring. PMID- 4204961 TI - [Transfer of the cytotoxic activity of lymphocytes immune to M. tuberculosis]. PMID- 4204963 TI - [Microbiological oxidation of 1,5-dimethylnaphthalene]. PMID- 4204962 TI - [Proliferation and migration of small intestine epithelial cells in paratyphoid infections]. PMID- 4204964 TI - The structure of the mitochondrial matrix. PMID- 4204965 TI - Changes of the ultrastructural pattern of the nucleus and nucleolus in regenerating rat liver. PMID- 4204966 TI - Organization of amphibian extraocular muscles. PMID- 4204967 TI - Ultrastructure of neurosecretory cells in the brain of the crab Rhithropanopeus harrisi (Gould). PMID- 4204968 TI - Periodicity of infectivity of plasmodial gametocytes: the "Hawking phenomenon". PMID- 4204969 TI - Experimental infection of African baboon (Papio cynocephalus) with Brugia malayi. PMID- 4204970 TI - A new biological assay, utilizing parasitic protozoa, for screening carcinogenic substances which induce bladder cancer in man and other mammals. PMID- 4204971 TI - Hepatitis B antigen-positive hepatitis in an Israeli family. PMID- 4204972 TI - "Contractile interstitial cells" in pulmonary alveolar septa: a possible regulator of ventilation-perfusion ratio? Ultrastructural, immunofluorescence, and in vitro studies. AB - In the lungs of healthy rats, humans, lambs, and monkeys, about 50% of the alveolar interstitial cells-resembling fibroblasts-contain bundles of fibrils measuring 30-80 A in diameter. Immunofluorescence studies on frozen sections of rat lung demonstrate that many interstitial cells bind sera containing antiactin antibodies. On account of these two sets of findings and our additional in vitro studies suggesting alveolar tissue contraction due to hypoxia or epinephrine, we postulate that the alveolar septa contain contractile cells different from that of smooth muscle. For these cells we propose the name of "contractile interstitial cells." Such cells lie within the thick portion of the air-blood barrier and around the pre- or postcapillary vessels. Hence it is possible that they play a role in the autoregulation of ventilation/perfusion (V/Q) ratio, particularly in hypoxic pulmonary hypertension. These findings, demonstrating a contractile system other than bronchial and arterial smooth muscle, suggest that the alveolus should no more be conceived as a passive "organ." PMID- 4204974 TI - Porous substructure of the glomerular slit diaphragm in the rat and mouse. AB - The highly ordered, isoporous substructure of the glomerular slit diaphragm was revealed in rat and mouse kidneys fixed by perfusion with tannic acid and glutaraldehyde. The slit diaphragm was similar in both animal species and appeared as a continuous junctional band, 300-450 A wide, consistently present within all slits formed by the epithelial foot processes. The diaphragm exhibited a zipper-like substructure with alternating, periodic cross bridges extending from the podocyte plasma membranes to a central filament which ran parallel to and equidistant from the cell membranes. The dimensions and spacing of the cross bridges defined a uniform population of rectangular pores approximately 40 by 140 A in cross section and 70 A in length. The total area of the pores was calculated to be about 2-3% of the total surface area of the glomerular capillaries. Physiological data indicate that the glomerular filter functions as if it were an isoporous membrane which excludes proteins larger than serum albumin. The similarity between the dimensions of the pores in the slit diaphragm and estimates for the size and shape of serum albumin supports the conclusion from tracer experiments that the slit diaphragm may serve as the principal filtration barrier to plasma proteins in the kidney. PMID- 4204973 TI - Isolation of ciliated or unciliated basal bodies from the rabbit oviduct. AB - Techniques have been developed for the isolation of basal bodies with cilia attached or for the isolation of only basal bodies from the rabbit oviduct. Oviducts are removed, cut open, and placed in an extraction medium composed of 0.25 M sucrose, 0.001 M EDTA, 0.025 M KCl, 0.02 M Hepes buffer pH 7.5, and 0.05% Triton X-100. After the oviduct is agitated in this medium on a Vortex mixer for (1/2) h, the lumenal cortex of each ciliated cell, containing 200-300 basal bodies with cilia attached, is released as a unit. The cortices and the intact nuclei, which are also released from the disrupted cells, form a pellet when the extraction medium is centrifuged at 600 g for 10 min. When cortices which contain only basal bodies are to be isolated, the oviduct is subjected to conditions which remove the cilia prior to being processed as above. The cilia are removed when the oviduct is placed in a medium of 0.25 M sucrose, 0.01 M CaCl(2), 0.02 M Pipes buffer pH 5.5, and 0.05% Triton X-100 and continuously agitated for 15 min on a Vortex mixer. The low pH and Ca(++) solubilize the transition region of the cilium and also prevent the cell from being disrupted. The cortices can be partially purified if the 600-g pellet is resuspended in 2.2 M sucrose pH 6.5 and centrifuged at 40,000 g for 2 h. Under these conditions, 85% of the nuclei form a pellet and the cortices float to the surface of the sucrose. In addition to the basal bodies or basal bodies with cilia, the cortices contain some adherent cytoplasm, a few fibers, and a few vesicles which may be remnants of mitochondria or endoplasmic reticulum. The structure of the cilia and the basal bodies isolated with either procedure is normal. PMID- 4204975 TI - Calcium and flagellar response during the chemotaxis of bracken spermatozoids. PMID- 4204976 TI - Macromolecular requirements for the initiation and maintenance of DNA synthesis during the cell cycle of Tetrahymena pyriformis. PMID- 4204977 TI - The subcellular distribution of lysosomal hydrolases in the Harding-Passey melanoma. PMID- 4204978 TI - Long-term studies of iron metabolism in normal males: comparison of red blood cell radioactivity with whole-body counter data. PMID- 4204979 TI - 99mTc-tetracyclines: preparation and biological evaluation. PMID- 4204980 TI - Use of 2-(4'-hydroxybenzeneazo)benzoic acid to study the binding of L-thyroxine to serum albumins. PMID- 4204981 TI - Biological significance of serum albumin binding parameters determined in vitro for clofibrate-related hypolipemic drugs: use of 2-(4'-hydroxybenzeneazo)benzoic acid to mirror L-thyroxine binding to and displacement from serum albumins. PMID- 4204983 TI - Absence of an electron microscopic substructure in intact flagella of Proteus mirabilis and Bacillus subtilis. PMID- 4204982 TI - In vitro hydrolysis of oxazepam succinate half-ester by a stereospecific soluble esterase from different animal species. PMID- 4204984 TI - [Letter: Sources of error in the Rh-determination]. PMID- 4204985 TI - [Methods and clinical importance of the detection of antibodies to spermatozoa (author's transl)]. PMID- 4204986 TI - Skeletal fluorosis and dietary calcium, vitamin C and protein. PMID- 4204987 TI - Proceedings: Physical data for electron therapy. PMID- 4204988 TI - Proceedings: Elective radiotherapy of the cervical region in carcinoma of the head and neck. PMID- 4204989 TI - The precipitin response induced in calves by a single experimental infection with Fasciola hepatica. PMID- 4204990 TI - A new intradermal test antigen for the diagnosis of contagious bovine pleuropneumonia. PMID- 4204991 TI - Calf immunoglobulins and congenital malformation. PMID- 4204992 TI - IgA immunoglobulin levels in porcine sera and mammary secretions. PMID- 4204993 TI - Plasma protein binding of digitoxin and digoxin in several mammalian species. PMID- 4204994 TI - Abnormal behavioural patterns in dogs with cleft palates. PMID- 4204995 TI - A sensitive, direct method for the measurement of water loss from body surfaces. PMID- 4204996 TI - Fibrin deposits in the Kiil dialyser. PMID- 4204997 TI - Food iron absorption in man. 3. Effect of iron salt, ascorbic acid and desferrioxamine on the isotopic exchange between native food iron and an extrinsic inorganic iron tracer. PMID- 4204998 TI - Pathophysiologic basis of therapy for shock and trauma syndromes: use of sequential cardiorespiratory measurements to describe natural histories and evaluate possible mechanisms. PMID- 4204999 TI - Therapy of nutritional failure. PMID- 4205000 TI - Radionuclide clearance techniques. PMID- 4205001 TI - Radiopharmaceuticals for renal studies. PMID- 4205002 TI - Uptake and removal of cortisol by canine erythrocytes in various electrolyte solutions. PMID- 4205003 TI - [Methods and dose distribution in electron therapy of malignant thyroid gland neoplasms]. PMID- 4205004 TI - [Biological modeling and criteria for standardization of whole-body vibration and noise]. PMID- 4205005 TI - [Treatment of skin cancer with fast electrons]. PMID- 4205006 TI - [Thyroid gland function during regression of experimental tumors under conditions of hypothalamic stimulation]. PMID- 4205007 TI - [Treatment of experimental tumors with laser beams in combination with fast electrons]. PMID- 4205008 TI - Sarcosporidiosis in psittaciformes. PMID- 4205009 TI - Studies on hydatidosis in Indian buffaloes (Bubalus bubalis). I. Some serological observations in natural infections of hydatids in buffaloes. PMID- 4205010 TI - Studies on hydatidosis in Indian buffaloes (Bubalus bubalis). II. Antigenicity of buffalo hydatid cyst fluid. PMID- 4205011 TI - The fine structure of the conducting system of the monkey heart (Macaca mulatta). I. The sino-atrial node and the internodal connections. PMID- 4205012 TI - Alteration of RNA synthesis in vitro with an endogenous regulating factor of cytodifferentiation of Streptomyces griseus. PMID- 4205013 TI - Induced production of beta-galactosidase in Streptomyces griseus. PMID- 4205014 TI - Effects of the oxathins DCMO and DCMOD on growth, proteins, oxidizing enzymes, and HCN production of low-temperature basidiomycete. PMID- 4205015 TI - Arhinencephaly unilateralis, uveal coloboma, and lens reduplication. PMID- 4205016 TI - Sequential studies of experimentally induced ovine listerial abortion: clinical changes and bacteriologic examinations. PMID- 4205017 TI - Sequential studies of experimentally induced ovine listerial abortion: pathologic changes. PMID- 4205018 TI - Ultrastructure of pulmonary alveoli of the calf. PMID- 4205019 TI - Immunization of dogs against human chorionic gonadotropin. PMID- 4205020 TI - Purification and characterization of hemolysin produced by Listeria monocytogenes. PMID- 4205021 TI - Clearing technique for preparation and photography of anatomic specimens of blood vessels of female genitalia. PMID- 4205022 TI - Effect of metabolic inhibitors on mesenteric arterial smooth muscle. PMID- 4205023 TI - The formation of H2-pteroate analogs from PABA-antagonists in a cell-free system of E. coli. PMID- 4205024 TI - Rubella: laboratory aspects. PMID- 4205025 TI - Present status of vaccines for rubella. PMID- 4205026 TI - Iatrogenic perforations of the esophagus. Therapeutic considerations. PMID- 4205028 TI - Propargyl amine-induced irreversibel inhibition of non-flavin-linked amine. PMID- 4205027 TI - Metabolic effects of hypoglycemic sulfonylureas. IV. Interference of sulfonylureas with mitochondrial oxidative phosphorylation. PMID- 4205030 TI - [The effect of emotional stress on the state of blood coagulation indices in simians]. PMID- 4205029 TI - Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides. PMID- 4205031 TI - [The effect of extirpation of the adrenals on changes in the perimural hydrolysis of carbohydrates in animals with sarcoma 45 and receiving thiophosphamide and 5 fluorouracil]. PMID- 4205032 TI - Pseudothrombocytopenia: manifestation of a new type of platelet agglutinin. PMID- 4205033 TI - Radioimmunoassay of calcitonin in human plasma. PMID- 4205034 TI - Quantitation of serum IgG by solid-phase radioimmunoassay. PMID- 4205035 TI - Variables in the laboratory diagnosis of Fabry's disease by measurement of methylumbelliferyl-alpha-galactosidase activity. PMID- 4205036 TI - Measurement of alpha 1-antitrypsin in serum, by immunodiffusion and by enzymatic assay. PMID- 4205037 TI - Quantitative determination of hepatitis B antigen by means of radial immunodiffusion. PMID- 4205038 TI - Antigen binding and complement fixing activity of IgM molecules reassociated in the presence and absence of J chains. PMID- 4205039 TI - Non-specific cytotoxicity by T cells activated with plant mitogens in vitro and the requirement for plant agents during the killing reaction. PMID- 4205041 TI - [Generalized tumorous lymph node amyloidosis with polyneuropathy and macroglobulinaemia (author's transl)]. PMID- 4205040 TI - Separation and characterization of cardiac antigen proteins. PMID- 4205042 TI - Periovulatory time courses of circulating gonadotropic and ovarian hormones in the rhesus monkey. PMID- 4205043 TI - [The lack of precision of thalamic stereotaxy based on Horsley and Clarke cranial coordinates in Macaca (author's transl)]. PMID- 4205044 TI - The application of the maize-derived gene competition model to the problem of dosage compensation in Drosophila. AB - The gene competition model, originally formulated from studies on the regulation of alcohol dehydrogenase activity in maize, is also applicable to the phenomenon of dosage compensation in Drosophila. The model accounts for the absence of dosage compensation in sex determination. PMID- 4205045 TI - Mutation induction in the male recombination strains of Drosophila melanogaster. AB - One group of the second chromosome lines isolated from a southern Texas population of Drosophila melanogaster, which has been known to show relatively high frequencies of male recombinations, was found to increase the frequency of sex-linked recessive lethal mutations from a control frequency of 0.18% to 1.63%. The second group, which showed a very much reduced frequency of male recombinations, was found to cause a slight increase to 0.48%, although it was not statistically significant. The first group was also tested for the recessive lethal mutation frequency in the second chromosome; the frequency increased from a control frequency of 0.28% to 2.82%. Mapping of a portion of the sex-linked lethals indicated a distribution along the entire X chromosome, although there was a tendency of clustering towards the tip of the X chromosome. One sex-linked lethal line so far tested was found to be associated with an inversion (approximate breakpoints, 14A-18A). It was suggested that the element causing male recombination might be similar to the hi mutator gene studied earlier by Ives (1950). PMID- 4205046 TI - Developmental and genetic studies on kynurenine hydroxylase from Drosophila melanogaster. AB - The level of kynurenine hydroxylase was measured throughout the development of wild type and the eye color mutants v, cn, st, ltd, cd, kar, w, ca, bri and p(P) of Drosophila melanogaster. In all cases except cn a bimodal distribution of enzyme activity during development was observed. Activity is initially detectable in second instar. A maximum is reached in early third instar. Activity declines prior to puparium formation. Shortly after pupation, activity rises dramatically to reach a maximum about five times the peak larval level. Maximum activity persists for a short time, and then falls sharply prior to emergence. No activity is detectable in cn, cn(3), or cn(35K). In pupae which have zero, one, two or three doses of the cn(+) allele, activity is proportional to the number of the + alleles. This provides further evidence that the cn locus contains the structural gene for kynurenine hydroxylase. Kynurenine hydroxylase is a useful gene product for studying the events of imaginal disc differentiation. PMID- 4205047 TI - The effects of disruptive and stabilizing selection on body size in Drosophila melanogaster. I. Mean values and variances. AB - Disruptive and stabilizing selection were applied to thorax and wing length in Drosophila melanogaster. Disruptive selection with negative assortative mating (D(-)) practiced on thorax length caused a large increase of the phenotypic variance; practiced on wing length the increase was less striking. Disruptive selection with random mating (D(R)) caused in most lines only a temporary increase in phenotypic variance, but mean values increased considerably. Stabilizing selection (S) on thorax length or wing length did not decrease the phenotypic variance, but the mean value of the selected character declined.-The proportion of flies emerging decreased in all lines, while development time increased. Variance of development time increased in the D(-)-lines. In both D(-) lines the frequency of flies with an abnormal number of scutellars was high (> 60% in one of the lines) and there was a temporary increase in abnormal segmentation of the abdomen. PMID- 4205048 TI - The effects of disruptive and stabilizing selection on body size in Drosophila melanogaster. II. Analysis of responses in the thorax selection lines. AB - An analysis was made of changes in mean and variance in some thorax selection lines. The decrease of mean thorax length in the stabilizing selection lines (S) was a consequence of a directional selection component, caused by the skewness of the frequency distributions. The slight or temporary increase of the phenotypic variance and the large increase of the mean value in the disruptive selection lines with random mating (D(R)) could be attributed to differences in reproduction between small and large flies (egg production and mating success). Phenotypic variability was high in two disruptive selection lines with compulsory mating of opposite extremes (D(-)). The mechanism of the change in variability was different in these replicate lines. In D(-)-1 the change was obtained by an increase of the environmental and the nonadditive genetic components of the variance. In D(-)-2 almost exclusively an increase of additive genetic variance occurred. PMID- 4205050 TI - Association of Bacillus cereus with food poisoning in dogs. PMID- 4205051 TI - Changes in -S-S- linked structures of the sperm tail during epididymal maturation, with comparative observations in sub-mammalian species. PMID- 4205053 TI - [Xylitol and possibilities of its clinical use]. PMID- 4205052 TI - On the recovery of adhesiveness by trypsin-dissociated cells. PMID- 4205054 TI - The kinetics and thermodynamics of death in multicellular organisms. PMID- 4205055 TI - Poor transformability with novr and eryr donor DNA of some mitomycin-C-sensitive strains of Haemophilus influenzae. PMID- 4205056 TI - Strong antimutagenic effects of fluoride on mutation induction by trenimon and I phenyl-3,3-dimethyltriazene in Drosophila melanogaster. PMID- 4205057 TI - The nature of chromosomal fragments in X-chromosomes of Drosophila melanogaster. PMID- 4205059 TI - [Essential hyperlipoproteinemia type I Grutz-Burger diagnosed in a 4-week-old infant (author's transl)]. PMID- 4205058 TI - Isometric training of rats--effects upon fast and slow muscle and modification by an anabolic hormone (nandrolone decanoate). I. Female rats. PMID- 4205060 TI - Putrescine metabolizing enzyme activities in some rat tissues during postnatal development. PMID- 4205061 TI - Studies of the heterogeneity of Streptomyces griseus protease. Isolation and characterization of an alkaline serine protease from commercial pronase-P derived from Streptomyces griseus K1. PMID- 4205062 TI - A rapid micro-assay of gentamicin, kanamycin or streptomycin in serum containing penicillins or cephalosporins. PMID- 4205063 TI - Aspects of the pharmacology of gentamicin during the neonatal period. PMID- 4205064 TI - Pseudomonas bacteremia. Evaluation of factors influencing response to therapy. PMID- 4205065 TI - The microbiology of gentamicin resistance. PMID- 4205066 TI - A new genus and species of cryptosporidiid Coccidia from India. PMID- 4205067 TI - Role of Pseudomonas aeruginosa in actinomycosis-like bovine mastitis. PMID- 4205068 TI - Pulmonary gas exchange following hemorrhagic shock and massive blood transfusion in the baboon. PMID- 4205070 TI - Nonketotic hyperglycemia and epilepsia partialis continua. PMID- 4205069 TI - Membrane leakage in Bacillus subtilis 168 induced by the hop constituents lupulone, humulone, isohumulone and humulinic acid. PMID- 4205071 TI - Purification and properties of a carotene co-oxidizing lipoxygenase from peas. PMID- 4205073 TI - Purification and some properties or erythrocyte carbonic anhydrase from the European moose. PMID- 4205072 TI - Protocatechuate 3,4-dioxygenase. IV. Preparation and properties of apo- and reconstituted enzymes. PMID- 4205074 TI - [Biochemical and rheological data in sputum. II. Biochemical definition of proteins in sputum (author's transl)]. PMID- 4205075 TI - Mucociliary abnormalities underlying impaired mucus elimination. PMID- 4205076 TI - Late prognosis of severe brain injury in children. PMID- 4205078 TI - [Localization of creatine kinase in skeletal muscle mitochondria]. PMID- 4205077 TI - Mechanisms of cerebrospinal fluid absorption. PMID- 4205079 TI - [Activation of DNA ligase in Bac. subtilis cells irradiated with ionizing radiation]. PMID- 4205080 TI - Dose and time dependent suppressive and enhancing effect of cytostatics in vitro on the target cell killing activity of lymphocytes. PMID- 4205081 TI - A century of progress in experimental leprosy. PMID- 4205082 TI - The kinetics and distribution of potassium in the toad bladder. PMID- 4205083 TI - Pathways for movement of ions and water across toad urinary bladder. I. Anatomic site of transepithelial shunt pathways. PMID- 4205084 TI - Urea transport in the toad bladder; coupling of urea flows. PMID- 4205086 TI - Congenitally obstructed bladders: fate after prolonged defunctionalization. PMID- 4205085 TI - A study of the dependence of the human erythrocyte glucose transport system on membrane sulfhydryl groups. PMID- 4205087 TI - Variation in bacteriuria with intestinal loop urinary diversions. PMID- 4205088 TI - Stone-containing pyelocaliceal diverticulum: embryogenic, anatomic, radiologic and clinical characteristics. PMID- 4205090 TI - Intravenous hyperalimentation: a useful adjunct in surgery of the azotemic patient. PMID- 4205089 TI - The negative effects of supervoltage external irradiation in prostatic carcinoma: report of 2 cases. PMID- 4205091 TI - [Role of the cerebellum in vestibulocardiac reactions in lower monkeys exposed to a rocking motion]. PMID- 4205092 TI - [Duodenal ulcer and polyglobulia]. PMID- 4205093 TI - [Significance of biopsy in Crohn's disease]. PMID- 4205094 TI - [Resection therapy of colonic diseases. Analysis of 238 cases (1967-1971)]. PMID- 4205095 TI - [Nonparasitic splenic cysts]. PMID- 4205096 TI - [Potassium determinations in kidney calculi]. PMID- 4205097 TI - [D-penicillamine therapy in liver diseases. Preliminary results in 44 cases]. PMID- 4205098 TI - [Penicillamine therapy of chronic liver diseases]. PMID- 4205099 TI - A gonadotropin inhibiting principle in the pineal of human fetuses. Evidence for its identity with arginine vasotocin. PMID- 4205100 TI - Lack of effect of steroids on thyrotropin-releasing hormone (TRH) mediated thyrotropin (TSH) release in man. PMID- 4205101 TI - [The occurrence of Sarcocystis miecheriana in swine. Frequency and distribution in part of Zealand (author's transl)]. PMID- 4205103 TI - [Surveillance of Rhesus factor immunized women. Management of pregnancy]. PMID- 4205102 TI - [Prostaglandins, a review (author's transl)]. PMID- 4205105 TI - Concomitant infection of albino mice by Trypanosoma cruzi and Schistosoma mansoni. Parasitological parameters. PMID- 4205104 TI - Preparation and use of malarial placenta antigen for immunodiffusion studies in a Nigerian population. PMID- 4205106 TI - Studies with the schistosomicide oxamniquine (UK-4271). II. Activity in primates. PMID- 4205107 TI - Letter: Plasma IgE levels and Schistosoma haematobium infection. PMID- 4205108 TI - Hepatozoon-like parasite (schizonts) in the myocardium of the domestic cat. PMID- 4205109 TI - Selective serum IgA deficiency. Frequency among 15,200 French blood donors. PMID- 4205110 TI - Neuraminidase and anti-neuraminidase serum: effect on the cell surface properties. PMID- 4205111 TI - Quantitative variation in the G antigen of the Rh blood group system. PMID- 4205112 TI - Independence of the Colton and Yt blood group systems. PMID- 4205113 TI - Establishment of new mouse and human pigmented melanoma lines in tissue culture. PMID- 4205114 TI - Harding-Passey melanoma in the BALB-C mouse as a model for studying the interactions between host macrophages and tumor cells. PMID- 4205116 TI - Biochemistry of melanin synthesis: in vivo effects of MSH on tyrosinase and melanogenesis of pigmentary system. PMID- 4205115 TI - Control of pigment synthesis in culture. PMID- 4205117 TI - Quantitative measurement of melanin as tyrosine equivalents and as weight of purified melanin. PMID- 4205118 TI - Regulatory mechanisms of tyrosinase activity in melanocyte. I. PMID- 4205119 TI - Histochemical evidence that peroxidase does not affect melanin formation in feather melanocytes. PMID- 4205120 TI - A revised concept of mammalian melanogenesis: the possible synergistic functions of aerobic dopa oxidase and peroxidase. A review. PMID- 4205121 TI - Purification and properties of tyrosinase isoenzymes from hamster melanoma. PMID- 4205122 TI - Peroxidase, "protyrosinase," and the multiple forms of tyrosinase in mice. PMID- 4205123 TI - The tyrosinase-protyrosinase system in frog epidermis. PMID- 4205124 TI - Hormonal control of melanocytes: MSH-sensitive adenyl cyclase in the Cloudman melanoma. PMID- 4205125 TI - Immunological studies on malignant melanomas of man. PMID- 4205126 TI - [A case of Schimmelpenning-Feuerstein-Mims' syndrome sith gradual development of cataract]. PMID- 4205127 TI - Effect of TRH (thyrotropin-releasing hormone) on the fine structure and replication of TSH and prolactin cells in the rat. PMID- 4205128 TI - [Comparative examination of Enterococci obtained from drinking water, foodstuffs and urine (author's transl)]. PMID- 4205129 TI - Antibacterial activity of diacetyl and its influence on the keeping quality of milk. PMID- 4205130 TI - Diffuse lymphoma of the intestines with a monoclonal gammopathy of IgG3 kappa type. PMID- 4205131 TI - Plasma cell interstitial pneumonia and macroglobulinemia. A response to corticosteroid and cyclophosphamide therapy. PMID- 4205132 TI - Waldenstrom's macroglobulinemia in a patient with a chronic biologic false positive serologic test for syphilis. PMID- 4205133 TI - Candida tropicalis and Torulopsis glabrata fungemia in a patient treated with long-term hyperalimentation. PMID- 4205135 TI - Disodium cromoglycate "Intal" (Fisons) "Rynacrom" (Fisons). PMID- 4205134 TI - [Tests of fetal pulmonary maturity and neonatal prognosis in normal and risk pregnancies. 3]. PMID- 4205136 TI - Connecticut gonorrhea screening program. PMID- 4205137 TI - Paraproteinemias. PMID- 4205138 TI - Active immunization to 17 beta-estradiol and its effects upon the reproductive cycle of the rhesus monkey. PMID- 4205139 TI - Thyroid activation in rats after intrapituitary administration of synthetic thyrotrophin-releasing factor (TRF). PMID- 4205140 TI - Delta 5-3 beta-hydroxysteroid dehydrogenase-delta 5-delta 4- isomerase activity in the corpus luteum of the pregnant rhesus monkey. PMID- 4205141 TI - The effect of fetal sex on placental biosynthesis of progesterone. PMID- 4205143 TI - Studies on different strains of vaccinia virus with particular reference to their quality regarding immunogenicity and reactogenicity. 3. Studies in rabbits and monkeys (Macaca mulatta). PMID- 4205142 TI - Metabolic effects of oral contraceptives in monkeys fed adequate protein & low proein diets. PMID- 4205144 TI - Genital listeriosis in Delhi (India): a pilot study. PMID- 4205145 TI - Antibody to hepatitis associated antigen in blood donors of Delhi by Sandwich solid phase radioimmunoassay. PMID- 4205146 TI - Editorial: The use of tears for heterozygote detection and genetic counseling. PMID- 4205147 TI - Statistical relationship between the presence of human subgingival anaerobic diptheroids and periodontal disease. PMID- 4205149 TI - [Studies on immunochemical determination of euglobulin fractionation from serum (author's transl)]. PMID- 4205148 TI - Two-stage model for human enamel demineralization as determined by scanning electron microscope analysis. PMID- 4205150 TI - Lack of mutagenicity of the cyclamate metabolites in Drosophila. PMID- 4205152 TI - Health insurance in Canada--an overview and commentary. PMID- 4205151 TI - Use of a hyperbaric solution for administration of intrathecal amphotericin B. PMID- 4205153 TI - Traumatic shock in man. PMID- 4205154 TI - Letter: Actions of propranolol in angina pectoris. PMID- 4205155 TI - Letter: Possible Chagas's disease in United States. PMID- 4205156 TI - Cisternograms in the primate Macaca mulatta. PMID- 4205157 TI - Local cerebral blood flow. PMID- 4205158 TI - Neglect after mesencephalic reticular formation lesions. PMID- 4205159 TI - Evaluation of patients with coronary artery disease. PMID- 4205160 TI - Specific injuries of sport. PMID- 4205162 TI - [Image of the lymphatic vessels in arthrography of the ankle joint]. PMID- 4205161 TI - [Angiographic image of the upper extremity in intermittent long-time hemodialysis in childhood]. PMID- 4205163 TI - [Gastric diverticula. Comments on a case of antral localization]. PMID- 4205164 TI - [Use of glibenclamide in different forms of diabetes mellitus]. PMID- 4205165 TI - Hemobilia. PMID- 4205166 TI - [Preparation and characteristics of the lysosomes of cultured chick embryo fibroblasts]. PMID- 4205167 TI - [Intensive disproportionate flow culture of Paramecium caudatum]. PMID- 4205168 TI - The value of laparotomy and splenectomy in the staging of 56 patients with Hodgkin's disease. PMID- 4205169 TI - [Hemoglobin, RNA, and protein synthesis in normal erythropoiesis]. PMID- 4205170 TI - Chromosome studies in paroxysmal nocturnal haemoglobinuria. PMID- 4205171 TI - A new unstable haemoglobin: Hb Buenos Aires, beta 85 (F1) Phe leads to Ser. PMID- 4205172 TI - Rhesus and squirrel monkey placental specific antigen(s). PMID- 4205173 TI - Estriol and estetrol in amniotic fluid. PMID- 4205174 TI - Present status of intrauterine diagnosis of genetic defects. PMID- 4205175 TI - [Waldenstrom's disease with mediastino-pulmonary and duodeno-pancreatic tumoral manifestations]. PMID- 4205176 TI - [Efficiency of the direct oriented sensitivity test based on quantitative bacilloscopic examination]. PMID- 4205178 TI - [Parenteral feeding in newborn infants and infants]. PMID- 4205177 TI - Formation of cyanide from o-chlorobenzylidene malononitrile and its toxicological significance. PMID- 4205179 TI - [How to treat uncomplicated asthma in adults]. PMID- 4205180 TI - Symptomatic relief of the pre-varicose syndrome and the symptomatology associated with varicose veins using ergot compounds. PMID- 4205181 TI - Ternidens deminutus (Railliet & Henry, 1909) and hookworm in Rhodesia and a review of the treatment of human infections with T. deminutus. PMID- 4205182 TI - [Effect of ionizing radiation on the anti-infective resistance of the organism and on natural immunity mechanisms]. PMID- 4205183 TI - Cell density as a selective parameter in tetrahymena. PMID- 4205185 TI - [Feto-maternal conflict in ABO, Rh and HL-A systems. IV. Birth weight]. PMID- 4205184 TI - Changes caused by air-drying and alcohol dehydration of spread insect sperm and fungal spore chromosome fibres. PMID- 4205187 TI - Measurement of the potency of allergy extracts by their inhibitory capacities in the radioallergosorbent test. PMID- 4205186 TI - [Molecular nitrogen fixation by microorganisms (review of work carried out in the USSR during the period 1966-1972)]. PMID- 4205188 TI - Increased circulating IgE in tropical eosinophilia. PMID- 4205189 TI - Temperature-induced derepression of tryptophan biosynthesis in a tryptophanyl transfer ribonucleic acid synthetase mutant of Bacillus subtilis. AB - A tryptophanyl-transfer ribonucleic acid (tRNA) synthetase (l-tryptophan: tRNA ligase adenosine monophosphate, EC 6.1.1.2) mutant (trpS1) of Bacillus subtilis is derepressed for enzymes of the tryptophan biosynthetic pathway at temperatures which reduce the growth rate but still allow exponential growth. Derepression of anthranilate synthase in a tryptophan-supplemented medium (50 mug/ml) is maximal at 36 C, and the differential rate of synthesis is 600- to 2,000-fold greater than that of the wild-type strain or trpS1 revertants. A study of the derepression pattern in the mutant and its revertants indicates that the 5 fluorotryptophan recognition site of the tryptophanyl-tRNA synthetase is an integral part of the repression mechanism. Evidence for a second locus, unlinked to the trpS1 locus, which functions in the repression of tryptophan biosynthetic enzymes is presented. PMID- 4205190 TI - Lactic acid translocation: terminal step in glycolysis by Streptococcus faecalis. AB - Streptococcus faecalis obtains metabolic energy chiefly from the conversion of glucose to lactic acid; the present experiments deal with the mechanism of lactic acid translocation across the cytoplasmic membrane. Efflux of [(14)C]lactate from preloaded cells was accelerated by raising the external pH, and also by the ionophores nigericin and valinomycin. These results suggest that lactate leaves the cell by an electroneutral process, presumably as lactic acid. Further evidence was obtained by studying the entry of [(14)C]lactate into nonmetabolizing cells. It appears that the membrane is essentially impermeable to the lactate anion, but allows passage of lactic acid. The most persuasive evidence is that, upon establishment of a pH gradient such that the cytoplasm was alkaline, l-[(14)C]lactate accumulated in the cells against the concentration gradient. Accumulation was transient, and dissipated in parallel with the collapse of the pH gradient. The concentration gradient attained at the peak was a function of the pH difference. Ionophores which are known to collapse a pH gradient, such as nigericin and valinomycin, abolished accumulation of l-lactate. We infer that lactic acid translocation, whether into the cells or outward, is an electroneutral process and for that reason the distribution of lactic acid across the membrane is a function of the pH of cytoplasm and medium. The specificity of translocation and its kinetic parameters suggest that it is mediated by a carrier of low specificity. PMID- 4205191 TI - Extrachromosomal elements in group N streptococci. AB - The deoxyribonucleic acid (DNA) of Streptococcus lactis C2, S. cremoris B(1), and S. diacetilactis 18-16 was labeled by growing cells in Trypticase soy broth containing (3)H-labeled thymine. The cells were gently lysed with lysozyme, ethylenediaminetetraacetic acid, and sodium lauryl sulfate. The chromosomal DNA was separated from plasmid DNA by precipitation with 1.0 M sodium chloride. The existence of covalently closed circular DNA in the three organisms was shown by cesium chloride-ethidium bromide equilibrium density gradient centrifugation of the cleared lysate material. In an attempt to correlate the loss of lactose metabolism with the loss of plasmid DNA, lactose-negative mutants of these organisms were examined for the presence of extrachromosomal particles. Covalently closed circular DNA was detected in the lactose-negative mutants of S. lactis C2 and S. diacetilactis 18-16. In S. cremoris B(1), however, no covalently closed circular DNA was observed by using cesium chloride-ethidium bromide gradients. Electron micrographs of the satellite band material from S. lactis C2 and its lactose-negative mutant confirmed the presence of plasmid DNA. Three distinct plasmids having approximate molecular weights of 1.3 x 10(6), 2.1 x 10(6), and 5.1 x 10(6) were observed in both organisms. PMID- 4205192 TI - Polyamine levels during growth, sporulation, and spore germination of Bacillus megaterium. AB - Spermidine was the major (>95%) polyamine of Bacillus megaterium in all stages of growth, although it could be replaced completely by spermine. Log-phase cells had 40 to 50% as much spermidine, based on ribonucleic acid (RNA) content, as did either stationary-phase cells or dormant spores; similar results were obtained in three other bacilli including an asporogenous mutant. Polyamine levels were essentially the same in B. megaterium grown in rich or poor media, or in media of high or low ionic strength. Polyamine levels were elevated three- to sixfold by exogenous spermidine without a major effect on growth, sporulation, or subsequent spore germination. During germination, the absolute amount of spermidine remained constant for almost 2 h until net RNA synthesis had lowered the polyamine/RNA ratio to a value close to that in log-phase cells. At this time, the spermidine level began to rise, and thereafter spermidine and RNA increased in parallel. This parallel relationship between the spermidine and RNA levels was abolished by actinomycin D, but not by chloramphenicol. PMID- 4205193 TI - Size distribution of the closed circular deoxyribonucleic acid molecules of Bacillus megaterium: sedimentation velocity and electron microscope measurements. AB - The circular deoxyribonucleic acid (DNA) of Bacillus megaterium was fractionated by sedimentation velocity on preparative zonal gradients. The fractions obtained were characterized by analytical sedimentation velocity analysis on neutral and alkaline sucrose gradients, and by contour length measurement by electron microscopy. Each fraction was found to contain circular molecules of one to three discrete sizes, in various combinations of covalently closed and open circular forms. Estimations of the molecular masses of these sizes gave values of 3.9, 6.2, 16.0, 31, and 60 million daltons for the major molecular species. Minor amounts of molecules of 7.6, 11.7, 47, 89, and 112 million daltons were observed in the electron microscope analyses. Length measurements of almost 600 molecules from the various fractions showed that all except six could be placed in distinct size classes. The distribution of molecular sizes in unfractionated circular DNA was shown to consist primarily of the two smallest size classes, although the relative proportions by weight of five of the classes were roughly equivalent. PMID- 4205194 TI - Magnesium transport in Bacillus subtilis W23 during growth and sporulation. AB - The active transport of magnesium by cells of Bacillus subtilis strain W23 occurs by a highly specific transport system (Mg(2+) is favored over Mn(2+), Co(2+), or Ca(2+)) that is energy dependent (i.e., glucose is required in minimal medium and the system is inhibited by cyanide and m-chlorophenyl carbonylcyanidehydrazone). The rate of magnesium uptake by log-phase B. subtilis cells follows saturation kinetics with a K(m) of 2.5 x 10(-4) M and a V(max) of 4.4 mumol per min per g (dry weight) at 30 C. Manganese is a competitive inhibitor showing a K(i) of 5 x 10(-4) M. During sporulation the rate of magnesium transport declines. This decline in rate is specific for the magnesium system as the manganese and calcium transport rates increase. The residual magnesium transport function in sporulating cells shows both an altered K(m) and an altered V(max). The magnesium content of late sporulating cells is also lower than that for log-phase cells. PMID- 4205195 TI - Transport of glucose, gluconate, and methyl alpha-D-glucoside by Pseudomonas aeruginosa. AB - Glucose transport by Pseudomonas aeruginosa was studied. These studies were enhanced by the use of a mutant, strain PAO 57, which was unable to grow on glucose but which formed the inducible glucose transport system when grown in media containing glucose or other inducers such as 2-deoxy-d-glucose. Both PAO 57 and parental strain PAO transported glucose with an apparent K(m) of 7 muM. Free glucose was concentrated intracellularly by P. aeruginosa PAO 57 over 200-fold above the external level. These data constitute direct evidence that glucose is transported via active transport by P. aeruginosa. Various experimental data clearly indicated that P. aeruginosa PAO transported methyl alpha-d-glucose (alpha-MeGlc) via the glucose transport system. The apparent K(m) of alpha-MeGlc transport was 7 mM which indicated a 1,000-fold lower affinity of the glucose transport system for alpha-MeGlc than for glucose. While only unchanged alpha MeGlc was detected intracellularly in P. aeruginosa, alpha-MeGlc was actually concentrated intracellularly less than 2-fold over the external level. Membrane vesicles of P. aeruginosa PAO retained transport activity for gluconate. This solute was concentrated intravesicularly several-fold over the external level. A component of the glucose transport system is believed to have been lost during vesicle preparation since glucose per se was not transported. Instead; glucose was converted to gluconate by membrane-associated glucose dehydrogenase and gluconate was then transported into the vesicles. Although this may constitute an alternate system for glucose transport, it is not a necessary prerequisite for glucose transport by intact cells since P. aeruginosa PAO 57, which lacks glucose dehydrogenase, was able to transport glucose at a rate equal to the parental strain. PMID- 4205196 TI - Regulation of aconitase synthesis in Bacillus subtilis: induction, feedback repression, and catabolite repression. AB - The synthesis of aconitase in Bacillus subtilis wild-type and different citric acid cycle mutants has been studied and the influence of various growth conditions examined. Aconitase is induced by citrate and precursors of citrate and repressed by glutamate. Induction and repression counteract each other, and at equimolar concentrations of citrate and glutamate, aconitase synthesis is unaffected. Induction by citrate can partly overcome catabolite repression of aconitase. Isocitrate dehydrogenase show endogenous induction of aconitase due to citrate accumulation. Leaky mutants defective in citrate synthase and aconitase cannot be induced by citrate, which indicates that they carry a regulatory mutation. The complex regulation of aconitase is discussed with reference to the participation of this enzyme in glutamate biosynthesis and energy metabolism. PMID- 4205197 TI - Physiological studies of Bacillus subtilis minicells. AB - Minicells produced by Bacillus subtilis strains carrying the div IV-B1 mutation, (CU 403 div IV-B1 and CU 403 div IV-B1, tag-1), were purified by a procedure which destroys parental cells with ultrasound, but spares minicells. Such preparations generally contain 10(9) or more minicells/ml and less than 10(4) colony-forming units/ml. Purified minicells are resistant to autolysis in tris(hydroxymethyl)aminomethane buffer, pH 7.5, at 30 C, conditions which result in total lysis of parental cells. Minicells are not completely devoid of autolytic activity, however. The medium in which minicells are produced, the temperature at which purified minicells are incubated, and the genotype of cells from which the minicells are derived all influence the rate of autolysis of purified minicells. These parameters are demonstrated by using minicells obtained from div IV-B1 and div IV-B1, tag-1 strains. Ultrastructural differences have been observed in the products of autolysis of these two minicell strains. Minicells are sensitive to low levels of lysozyme and yield miniprotoplasts when the wall is removed in an osmotically protective environment. Although minicells are unable to grow, they can maintain their integrity over long periods of time, which suggests functional energy metabolism in minicells. Direct measurements of adenosine 5'-triphosphate (ATP) levels by the luciferase assay indicated that minicells can produce ATP. Oxygen consumption, measured by standard respirometry techniques, also indicates functional metabolism in minicells. These findings demonstrate that minicells purified by ultrasound are suitable material for study of physiological processes in anucleate cells. PMID- 4205198 TI - Cell wall turnover at the hemispherical caps of Bacillus subtilis. AB - Cell walls made by Bacillus subtilis bacteria grown in D(2)O medium have buoyant densities in CsCl which are different from walls made by cells grown in H(2)O medium. Cell wall turnover was studied by measuring the change in wall buoyant density after a B. subtilis culture was shifted from growth in D(2)O medium to aeration in H(2)O medium. Walls from the hemispherical caps were isolated after preferential digestion of wall from the cylindrical regions using the B. subtilis autolytic amidase. The walls from the polar regions were found to turn over extensively. PMID- 4205200 TI - Degradation of thymidine by Lactobacillus acidophilus. AB - Whole cells of Lactobacillus acidophilus are capable of degrading thymidine to thymine, suggesting the presence of thymidine phosphorylase (or thymidine hydrolase). This activity was also demonstrated in cell-free extracts. PMID- 4205201 TI - Degree of completion of 3'-terminus of transfer ribonucleic acids of Bacillus subtilis 168 at various developmental stages and asporogenous mutants. AB - Transfer ribonucleic acids from sporulating cells, spores, sporangia, or stationary-phase asporogenous mutants of Bacillus subtilis all showed a deficiency in the 3'-terminal adenosine moiety. PMID- 4205199 TI - Chemical composition and ultrastructure of native and reaggregated membranes from protoplasts of Bacillus cereus. AB - Conditions were defined for producing protoplasts with lysozyme and isolating the protoplast membranes from cells of Bacillus cereus T harvested late in the exponential growth phase just before sporogenesis. The membranes contained approximately 60% protein, 30% lipid, 6% carbohydrate, and 1% ribonucleic acid. Seventeen proteins were distinguished by molecular size in the membrane solubilized with sodium dodecyl sulfate, and 12 in that with phenol and acetic acid. The lipid fraction consisted of neutral lipids (28%) and phospholipids (72%). Four phospholipids were identified: diphosphatidyl glycerol, phosphatidyl ethanolamine, phosphatidyl glycerol, and lysophosphatidyl ethanolamine. Eighteen fatty acids were identified, with a predominance of branched C(15) and C(17) and of normal C(16) acids. The carbohydrate fraction consisted of neutral hexoses. A clear supernatant solution from the solubilized preparation became reaggregated into membrane by dialysis in the presence of MgCl(2). The reaggregated membrane had the same main components as the native membrane, but the amount and ratio of protein and lipid depended on the buffer and the MgCl(2) concentration. By electron microscopy, the reaggregated membranes appeared as vesicles or sheets, depending on the MgCl(2) concentration. Hexagonal lattices were occasionally detected in the negatively stained ultrastructure of both native and reaggregated membrane fragments. PMID- 4205202 TI - The effect of anti-plasma cell serum on B cells. PMID- 4205203 TI - Characteristics of secretory immune system in human middle ear: implications in otitis media. PMID- 4205204 TI - Early appearance of sensitized lymphocytes in mice infected with Listeria monocytogenes. PMID- 4205205 TI - Polyribitol-phosphate: an antigen of four gram-positive bacteria cross-reactive with the capsular polysaccharide of haemophilus influenzae type B. PMID- 4205206 TI - The role of T lymphocytes in the primary humoral antibody response to brucellin. PMID- 4205208 TI - Cytotoxic antibodies and lymphocytes induced by orthotopic tooth bud allografts in mice. PMID- 4205207 TI - Activation of the classic and alternate complement pathways by endotoxin. PMID- 4205209 TI - Interaction of complement with antigen-antibody complexes of rabbit allotypic antigens and their corresponding antibodies. PMID- 4205210 TI - Immunosuppressive effects of anti-lymphocyte serum in complement deficient mice. II. Evidence that activity is mediated by C3 independent antibodies. PMID- 4205211 TI - [Modern methods for fractionation and isolation of proteins (author's transl)]. PMID- 4205213 TI - Hypothalamic input to supraoptic neurons. PMID- 4205212 TI - [Electron microscope findings in hyperoxia (author's transl)]. PMID- 4205214 TI - Grey's Hospital: the oldest hospital on its original site in the Republic. PMID- 4205215 TI - [Double-blind comparative study of sulfamethoxazole-trimethoprim and demethylchlortetracycline in the treatment of urinary infections]. PMID- 4205216 TI - [Experimental studies on rheumatic fever: relationship between Streptococcus hemolyticus and the body response]. PMID- 4205218 TI - [Prevention of the obstetric risk]. PMID- 4205217 TI - Immunofluorescent demonstration of bacterial antigen in experimental pyelonephritis with antiserum against common enterobacterial antigen. PMID- 4205219 TI - [Research on the ultrastructure of certain strains of Mycobacteria isolated from tuberculosis patients, with different sensitivity to isoniazid and streptomycin]. PMID- 4205220 TI - [The latex test in the detection of Au antigen associated with hepatitis (HAA)]. PMID- 4205222 TI - [Proceedings: Roentgen diagnostic methods in their significance for therapy of cervix carcinoma. Lymphography]. PMID- 4205221 TI - [Proceedings: Blood group incompatibility and fertility]. PMID- 4205223 TI - [Proceedings: Serum ceruloplasmin during use of oral contraceptives]. PMID- 4205224 TI - [Proceedings: Demonstration of alpha-1 fetoprotein and placenta proteins in gynecologic tumor patients]. PMID- 4205225 TI - [Proceedings: Demonstration of human antibody forming cells against Rh positive erythrocytes]. PMID- 4205226 TI - [Proceedings: Occurrence and functional significance of nerves in human endometrium]. PMID- 4205227 TI - A new federal financial formula: an interview with the Minister of National Health and Welfare. PMID- 4205228 TI - Psychiatric care of the disadvantaged child in a private practice setting. PMID- 4205229 TI - Suppressive effect of concurrent administration of metal salts on carcinogenesis by 3'-methyl-4-(dimethylamino)azobenzene, and the effect of these metals on aminoazo dye metabolism during carcinogenesis. PMID- 4205230 TI - Disturbance of immune system in mice by administration of 7,12 dimethylbenz(a)anthracene and normal thymocytes. PMID- 4205231 TI - [Static and dynamic distribution of sevin in the environment]. PMID- 4205232 TI - [Case of renal cancer associated with marked calcification and ossification]. PMID- 4205233 TI - [Intra-cavitary high energy radiotherapy]. PMID- 4205234 TI - [Coincidence of Rh-isoimmunization, diabetes and pregnancy]. PMID- 4205235 TI - [Long-term training effects in chronic ischemia]. PMID- 4205236 TI - [Comparative evaluation of the methods for determining the toxigenicity of diphtheria corynebacteria]. PMID- 4205238 TI - [Lysis of blue-green algae by an agent of nonviral character]. PMID- 4205237 TI - [Comparison of the antimicrobial properties of sorbic and beta-styrylacrylic acids and their sodium salts]. PMID- 4205240 TI - Growth of the blue-green alga Tolypothrix tenuis as affected by cobalt and molybdenum. PMID- 4205239 TI - [Antigenic structure of plasma membranes of mouse liver cells. I. Isolation of total fractions of lipids and proteins from liver cell membranes and study of their antigenic activity]. PMID- 4205241 TI - Effect of copper on the composition of bacterial cell wall peptides. PMID- 4205242 TI - Production of bacterial amylase on some commercial materials. PMID- 4205243 TI - Optimal conditions for production of bacterial amylase. PMID- 4205244 TI - Relationship between soybean cultivars and Rhizobium japonicum serotypes with single- and multi-strain inoculants. I. Greenhouse pot experiments. PMID- 4205245 TI - Further investigations on hydroxyproline excretion in bovine puerperal paresis. PMID- 4205246 TI - [Studies on the site of intestinal Cu absorption]. PMID- 4205248 TI - On the biometry of spermatozoa from different levels of the reproductive tract of buffalo bulls. PMID- 4205247 TI - The influence of selenium administration on copper levels and growth of lambs. PMID- 4205249 TI - A kininogen-kinin like reaction revealed by the marginal distance of the equine lung. PMID- 4205250 TI - Histological and histoenzymochemical aspects of ocular tumours in cattle. PMID- 4205251 TI - [Blood circulation in the German cultivated domestic pig]. PMID- 4205252 TI - [Studies on the function of the forestomach of Muridae. II. Effect of the microflora on pH level and alpha-amylase activity in the rat forestomach. Studies on germ-free animals]. PMID- 4205253 TI - [Isolation of L-forms from the cerebrospinal fluid of patients with epidemic cerebrospinal meningitis]. PMID- 4205254 TI - [Forms of persistance of tuberculosis mycobacteria in healthy subjects with regard to human tuberculosis]. PMID- 4205255 TI - [Isolation of the A-antigen of the tularemia microbe]. PMID- 4205257 TI - [Use of the phage typing method and the corycin test for studying the spreading characteristics of non-toxigenic corynebacteria, related to C. diphtheriae in a children's collective]. PMID- 4205256 TI - [Preparation of immunosorbents for viruses and rickettsia using glutaraldehyde (GA) and ethylchlorformate (EC)]. PMID- 4205259 TI - Cysts of the spinal ganglia. PMID- 4205258 TI - [The physico-chemical properties and allergenic activity of peptides of various species of bacteria]. PMID- 4205261 TI - [Bacteriological, serological, and socio-medical study of 19 cases of acute meningococcal infection. Preparatory note]. PMID- 4205260 TI - [Transmission of epidemic cerebrospinal meningitis]. PMID- 4205263 TI - [In vitro sensitivity of meningococci and the implications for prevention]. PMID- 4205264 TI - [Bacteriological diagnosis of meningococcal infections. Technics for rapid identification and diagnosis]. PMID- 4205262 TI - [N. meningitidis strains isolated in Belgium between 1969 and 1972]. PMID- 4205265 TI - [Sampling methods in the isolation of N. meningitidis]. PMID- 4205266 TI - [Effect of prostaglandin F 2 alpha on sea urchin embryos at early stages of development and their sensitivity to neuropharmacological agents]. PMID- 4205267 TI - Toxoplasmosis: an overview. PMID- 4205269 TI - New appraoch to save health care costs. PMID- 4205268 TI - Laboratory animal anaesthesia. PMID- 4205270 TI - Nonrheumatic valvular cardiac disease: a clinicopathologic survey of 27 different conditions causing valvular dysfunction. PMID- 4205271 TI - [Flexible esophagoscopy]. PMID- 4205272 TI - [Releasing hormone]. PMID- 4205273 TI - [Anomaly of pituitary TSH releasing reserve]. PMID- 4205274 TI - [TSH secretion dynamics in hyperthyroidism]. PMID- 4205275 TI - [Experimental and clinical examination of blood TSH determination by radioimmunoassay (including TRH test)]. PMID- 4205276 TI - Differential effects of chromonar and nitroglycerin on intramyocardial oxygen tension. PMID- 4205278 TI - A method of freeze-drying and fixing spermatozoa for electron microscopy. PMID- 4205277 TI - Vaccinia virus morphogenesis: a comparison of virus-induced antigens and polypeptides. PMID- 4205279 TI - [A trial to improve a niacin test paper (author's transl)]. PMID- 4205280 TI - [Studies on the isolation culture technique of tubercle bacilli applicable in remote areas. 1 (author's transl)]. PMID- 4205281 TI - [Factors influencing the minimal inhibitory concentration of rifampicin for Mycobacterium tuberculosis (author's transl)]. PMID- 4205282 TI - [Open non-gunshot fractures and fracture-dislocations of the ankle joint]. PMID- 4205283 TI - The effect of diphosphonate on calcium phosphate crystallization in urine in vitro. PMID- 4205284 TI - [Evaluation of the bactericidal action of benzalkonium chloride using a multiple site culture injector]. PMID- 4205285 TI - [Determination of the bactericidal activity of benzalkonium chloride by counting the survivors after neutralization of the antiseptic]. PMID- 4205286 TI - [Asimple apparatus for measuring the efficiency of quick acting disinfectants and sterilizing solutions. Application to the action of sodium hypochlorite against bacterial spores]. PMID- 4205287 TI - The kinetics of synthesis and degradation of aspartate aminotransferase isozymes in rat peripheral red blood cells during cytodifferentiation. PMID- 4205288 TI - Blood group antigens I, i, H and HI on monkey, rabbit and guinea pig erythrocytes. PMID- 4205289 TI - The effect of intravenous hyperalimentation on erythrocyte lipids. PMID- 4205290 TI - Tyrosinase activity in a highly pigmented human melanoma and in negro skin. PMID- 4205291 TI - [Approaches to modeling in animal experiments the length of time of human irradiation]. PMID- 4205292 TI - Prevention of microbial catheter contamination in patients receiving parenteral hyperalimentation. PMID- 4205293 TI - Primary reticulum cell sarcoma of the femur: 12-year follow-up after radiation therapy and pathologic fracture. PMID- 4205294 TI - In vitro specificity and in vivo activity of antimacrophage serum. PMID- 4205295 TI - [Diverticula of the ureter]. PMID- 4205296 TI - On the levels of hemoglobins F and A2 in sickle-cell anemia and some related disorders. PMID- 4205297 TI - Total balanced intravenous feeding by peripheral veins in paediatric surgery. A summary of 7 years' research and clinical experience. PMID- 4205298 TI - [Protective efficacy of some inactivated oral bacterial vaccines]. PMID- 4205299 TI - [Study on chimpanzees on the efficacy of an oral typhoid immunization with an inactivated antigen]. PMID- 4205300 TI - [Immunologic interactions between some bacterial inactivated oral vaccines. II. Antibody response in the rabbit]. PMID- 4205301 TI - Inhibition of microsomal drug metabolism by anticholinesterase insecticides. PMID- 4205302 TI - Insecticides, polychlorinated biphenyls and mercury in wild cormorants, pelicans, their eggs, food and environment. PMID- 4205303 TI - Uptake and accumulation of DDT and PCB by Ephemera danica (Ephemeroptera) in continuous-flow systems. PMID- 4205304 TI - Molybdenum toxicity: abnormal cellular division of teratogenic appearance in Euglena gracilis. PMID- 4205305 TI - Chlorinated hydrocarbons in plankton from the Gulf of Mexico and Northern Carribbean. PMID- 4205306 TI - Discharge planning; an asset in the continuum of patient care services. PMID- 4205307 TI - [FTA test with sera from various animal species]. PMID- 4205308 TI - The HMO in perspective. PMID- 4205309 TI - IgE and IgG antibodies against Aspergillus fumigatus in sera of patients with bronchopulmonary allergic aspergillosis. PMID- 4205310 TI - Immuno- and physicochemical studies of an IgA-IgG mixed cryoglobulin. PMID- 4205311 TI - Limb immobilization devices for chaired waking monkeys. PMID- 4205312 TI - Industrial chemicals. Extraction of polychlorinated biphenyls: evaluation of a column technique applied to polar bear and seal tissue. PMID- 4205313 TI - Folate coenzymes of Lactobacillus casei and Streptococcus faecalis. PMID- 4205314 TI - Kinetic mechanism of glycogen synthase D from human polymorphonuclear leukocytes. PMID- 4205315 TI - Homocysteine biosynthesis in green plants. O-Phosphorylhomoserine as the physiological substrate for cystathionine gamma-synthase. PMID- 4205317 TI - Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R. Biochemical and biophysical properties of methionine transfer ribonucleic acid. PMID- 4205316 TI - The carboxypeptidase-dependent inactivation of thymidylate synthetase. PMID- 4205318 TI - Studies of membrane formation in Tetrahymena pyriformis. The biosynthesis of proteins and their assembly into membranes of growing cells. PMID- 4205319 TI - Separation of dihydroergotoxine (hydergine) into dihydroergocornine, dihydroergocryptine and dihydroergocristine by counter-current distribution. PMID- 4205321 TI - Whirlpool therapy for the treatment of soft tissue wounds complicating extremity fractures. PMID- 4205320 TI - Functional localization in the trigeminal root. PMID- 4205322 TI - Letter: Urethritis at a regional VD clinic. PMID- 4205323 TI - [Clinical use of a method of whole-body radiometry for a study of Na24 metabolism]. PMID- 4205324 TI - Cryosurgery of respiratory structures. II. Cryonecrosis of the lung. PMID- 4205325 TI - Another generation gap: physicians vs. the elderly. PMID- 4205326 TI - Low dose prophylactic antibiotics in vaginal hysterectomy. PMID- 4205327 TI - The effect of anticoagulants on the dialysis method of measurement of vitamin B 12 binding capacity of plasma proteins. PMID- 4205329 TI - Diagnosis and incidence of Neisseria gonorrhoeae in Cape coloured females in the Western Cape. Laboratory aspects. PMID- 4205328 TI - [Morphofunctional study of monkey reproductive organs following a single irradiation]. PMID- 4205330 TI - [Problems of immunity in dermatomycoses of animals]. PMID- 4205331 TI - [Colostral immunity against Aujeszky's disease and paratyphoid]. PMID- 4205332 TI - [Development cycle of sarcocysts]. PMID- 4205333 TI - [Disinfection of bull sperm of Bacillus pyocyaneus]. PMID- 4205334 TI - [Bacterial food poisoning caused by Bac. cereus]. PMID- 4205335 TI - [Effect of parenteral nitrogen nutrition on the metabolism of liver tissue]. PMID- 4205336 TI - Metabolism of 14C-histamine in amphibians (Bufo bufo) and reptiles (Pseudemys scripta and Testudo hermanni). PMID- 4205337 TI - Application of Cu(II) ions for an indicator reaction in volumetric methods of drug assay. VI. Quantitative determination of the active substance in spasmophen and spasmophen-duplex. PMID- 4205338 TI - A comparison of retinal argon laser lesions in man and in cynomolgus monkey. PMID- 4205339 TI - [First disjunction zone of the lens in glaucoma patients (author's transl)]. PMID- 4205340 TI - Double-mind theory. PMID- 4205341 TI - [Respective values of serum folic, erythrocyte and folinic activities as a test of folate storage and metabolism in the normal and premature infant]. PMID- 4205342 TI - [Half-life of unlabeled insulin in the normal child and diabetic child in ketosis]. PMID- 4205343 TI - [Kniest's disease]. PMID- 4205344 TI - Type-A influenza viruses isolated from wild free-flying ducks in California. PMID- 4205345 TI - Pathology and prevention of Leucocytozoon smithi infection of Turkeys. PMID- 4205346 TI - Immunization against Marek's disease: influence of strain of chickens, maternal antibody, and type of vaccine. PMID- 4205347 TI - A comparison of the prophylactic efficacy of lyophilized and cell-associated turkey herpesvirus against Marek's disease. PMID- 4205348 TI - Effects of Eimeria acervulina on intestinal pH in conventional and gnotobiotic chickens. PMID- 4205349 TI - Primary dietary prevention of atherosclerosis. PMID- 4205350 TI - Hospital food and possibilities of its improvement. Clinical aspects. PMID- 4205351 TI - Biosynthesis of immunoglobulin A (IgA). Secretion and addition of carbohydrate to monomer and polymer forms of a mouse myeloma protein. AB - Cell suspensions of mouse plasma-cell tumour MOPC 315 secreting predominantly IgA (immunoglobulin A) monomer and dimer were incubated with radioactive leucine, mannose, galactose and fucose for various periods of time. The amounts of secreted and intracellular immunoglobulins were measured by co-precipitation with specific antibody, and the molecular species present were assessed by electrophoresis in polyacrylamide gels. Analysis of the secreted myeloma protein demonstrated that monomer and dimer IgA molecules are identical with respect to carbohydrate composition and rate of secretion. Within the cell, the myeloma protein is almost entirely accounted for by monomer units which either leave the cell as such or are polymerized with the addition of J chain close to the time of secretion. The results support the concept of a stepwise addition of carbohydrate residues to IgA immunoglobulin during the process of secretion. Similar patterns of carbohydrate assembly were found for the monomer or dimer molecules. Mannose residues are added at an early stage, whereas fucose is added close to the time of secretion. Galactose is also added early, but some may also be incorporated at a later stage. Control of IgA polymerization is considered unlikely to reflect regulation at the level of carbohydrate addition, and it is suggested that the critical controlling factor is the J chain. PMID- 4205352 TI - Biosynthesis of immunoglobulin A (IgA) and immunoglobulin M (IgM). Requirement for J chain and a disulphide-exchanging enzyme for polymerization. AB - Mouse myeloma cells secreting 19S IgM (immunoglobulin M) (MOPC 104E and TEPC 183) or monomer and polymer IgA (immunoglobulin A) (MOPC 315) were incubated with radioactive leucine and the intracellular and secreted immunoglobulins and immunoglobulin subunits were prepared by preparative sucrose-density-gradient centrifugation. Samples were reduced in the presence or absence of isolated J chain, passed over Sephadex G-25 and then incubated at 37 degrees C for 30min with or without a source of disulphide-interchange enzyme. The extent of reassembly of reduced subunits was then evaluated by electrophoresis in polyacrylamide gels. Provided that J chain and the disulphide-interchange enzyme were supplied, both IgM and IgA could be assembled from their respective subunits, obtained by reductive cleavage of polymeric forms. Under similar conditions, assembly of polymeric forms from intracellular or secreted 7S monomer subunits also occurred. Under these conditions polymerization was total, there being no residue of the monomeric form. Reassembly did not occur in the absence of either J chain or the enzyme. All of the J chain released from IgM by reductive cleavage was incorporated back into the reassembled polymer. The J chain is therefore likely to be an essential structural requirement for polymeric immunoglobulins. A variety of controls ruled out non-specific interactions, and further suggested that the amino acid sequence of polypeptide chains determines the specificity of polymerization. The fact that intracellular IgA and IgM monomer subunits known to be deficient in galactose and fucose can be completely polymerized suggests that the addition of carbohydrate does not control polymerization. PMID- 4205353 TI - Biosynthesis of immunoglobulin A (IgA) and immunoglobulin M (IgM). Control of polymerization by J chain. AB - Cell suspensions of mouse plasma-cell tumours secreting IgA (immunoglobulin A) and IgM (immunoglobulin M) were incubated with radioactive leucine for various periods of time. The secreted immunoglobulins were precipitated from the culture medium with specific rabbit antisera to determine the relative distribution of radioactivity among the different molecular species, and to estimate the fraction of total radioactivity in the J chain. For IgM-secreting cells there is a balanced synthesis of 7S subunits and J chains, and the secreted product is uniformly assembled to the pentamer. In cells secreting IgA, however, the results demonstrate that the pool of intracellular J chain is less than the intracellular IgA pool. The concentration of J chain is therefore limiting and is less than the requirement for complete polymerization. The major factor that determines whether an intracellular monomer is secreted as such or is polymerized with the addition of J chain is therefore the amount of intracellular J chain. When this is limiting, as it is in cells secreting IgA, then monomer will be secreted. PMID- 4205354 TI - Effect of methylglyoxal bis(guanylhydrazone) on polyamine metabolism in normal and regenerating rat liver and rat thymus. AB - 1. Injections of sublethal doses of methylglyoxal bis(guanylhydrazone), a potent inhibitor of putrescine-activated S-adenosylmethionine decarboxylase in vitro, resulted after a few days in an immense increase in the activity of S adenosylmethionine decarboxylase in normal and regenerating rat liver and in rat thymus. The increase in the activity of S-adenosylmethionine decarboxylase was at least partly due to a marked lengthening of the half-life of the enzyme. 2. In regenerating liver and thymus there was also a moderate stimulation of the activity of ornithine decarboxylase (EC 4.1.1.17) and a marked accumulation of tissue putrescine. 3. Injection of methylglyoxal bis(guanylhydrazone) into the rat also markedly decreased the activity of diamine oxidase (EC 1.4.3.6) in thymus. 4. In no cases where doses of methylglyoxal bis(guanylhydrazone) close to the LD(50) dose for the rat were used was it possible to lower tissue spermidine content to any significant extent. 5. Methylglyoxal bis(guanylhydrazone) seemed to act as a competitive inhibitor for the substrate S-adenosylmethionine and as an uncompetitive inhibitor for the activator putrescine in the decarboxylation of S-adenosylmethionine in vitro. 6. In the diamine oxidase reaction, with putrescine as the substrate, methylglyoxal bis(guanylhydrazone) was a non competitive inhibitor for putrescine. PMID- 4205356 TI - [The variability of Actinomyces aureoverticillus 1306]. PMID- 4205355 TI - [The fibrinolytic and thrombolytic activity of the mold fungi of the genus Aspergillus]. PMID- 4205357 TI - Varying persistence of polychlorinated biphenyls in six California soils under laboratory conditions. PMID- 4205358 TI - A search for polychlorinated biphenyls in human milk in rural Colorado. PMID- 4205360 TI - Effects of pH, light and temperature on carbaryl in aqueous media. PMID- 4205361 TI - Embryotoxic effects of three PCB'S in the chicken. PMID- 4205359 TI - Tests of pesticidal synergism with young pheasants and Japanese quail. PMID- 4205362 TI - PCB and hydrocarbon contamination of plankton by nets. PMID- 4205363 TI - A qualitative method for detecting hydroxylated metabolites of polychlorinated biphenyls. PMID- 4205364 TI - Outer (cell wall) membrane proteins of Pseudomonas aeruginosa. PMID- 4205365 TI - Demonstration of delayed hypersensitivity to Neisseria meningitidis. PMID- 4205366 TI - "Whither medicine in Rhodesia". PMID- 4205367 TI - New thoughts for old. II. PMID- 4205368 TI - Comparison of preparations of erythrocyte membranes and membrane proteins by SDS gel electrophoresis. PMID- 4205369 TI - Precipitating antibody against core glycolipid of Enterobacteriaceae. PMID- 4205370 TI - Orosomucoid, seromucoid and haptoglobin in serum during adjuvant arthritis of the rat. PMID- 4205371 TI - Intracavitary electron beam therapy for cancer of the uterine cervix: dose distribution study and clinical result. PMID- 4205372 TI - Parenteral hyperalimentation in gynecologic oncology patients. PMID- 4205373 TI - Letter: Susceptibility to damage from impulse noise: chinchilla versus man or monkey. PMID- 4205374 TI - Antimetabolites produced by microorganisms. VII. L-(N5-phosphono)methionine-S sulfoximinyl-L-alanyl-L-alanine. PMID- 4205375 TI - Studies on the antiviral substance. Mechanism of action of bihoromycin, a new antibiotic. PMID- 4205376 TI - Fluorescence studies on the interaction between heavy meromyosin and magnesium ions. Effect of EDTA. PMID- 4205378 TI - [Modern counseling. I. On Professor Masaki]. PMID- 4205377 TI - Ionic changes during smooth muscle fixation for electron microscopy. PMID- 4205379 TI - [Staff conference by the nursing station of the Department of Internal Medicine, Hokkaido University Hospital. Changes in the patient's needs]. PMID- 4205380 TI - [A midwife's personal experience in miscarriage]. PMID- 4205382 TI - [Utilization of retired nurses]. PMID- 4205381 TI - [Discussion: utilization of retired nurses]. PMID- 4205383 TI - [Reactivation of retired nurses]. PMID- 4205384 TI - [Reactivation of retired nurses. 1. Survey on retired nurses in Kanagawa Prefecture]. PMID- 4205385 TI - [Reactivation of retired nurses. 2. Opening of a free employment office in cooperation with the Ibaragi Prefectural Association of Assistant Nurses]. PMID- 4205386 TI - [Reactivation of retired nurses: a part time employment on an every-other-day schedule]. PMID- 4205387 TI - [Reactivation of retired nurses: a part time employment and understanding attitude of the work environment]. PMID- 4205388 TI - [Reactivation of retired nurses: encouragement of a friend as a deciding factor in returning to nursing]. PMID- 4205389 TI - [Reactivation of retired nurses: importance of attractive wages and availability of a nursery]. PMID- 4205390 TI - [Reactivation of retired nurses: return to full time employment at a psychiatric ward after an absence of 25 years]. PMID- 4205391 TI - [Bedside nursing. Attendance of an aged blind, mute patient--understanding of the needs of the patient with pharyngeal cancer following tracheotomy]. PMID- 4205393 TI - [Bedside nursing. Attendance of a puerperal patient uncooperative in breast feeding]. PMID- 4205392 TI - [Bedside nursing. Attendance of an asthmatic child under acute psychological stress]. PMID- 4205394 TI - [Bedside nursing. Nursing of a patient with psychiatric symptoms following gastrectomy]. PMID- 4205396 TI - [Human chromosomes. I]. PMID- 4205395 TI - [Birth rate]. PMID- 4205397 TI - [Speech and aphasia]. PMID- 4205398 TI - [Transfer technic. 6. Transfer of a patient by more than 2 attendants]. PMID- 4205400 TI - [Discussion: man and death]. PMID- 4205399 TI - [Homeostasis]. PMID- 4205401 TI - [Team work in the care of the dying patient]. PMID- 4205402 TI - [Psychology of dying patients]. PMID- 4205403 TI - [Bedside nursing. Nursing of a juvenile diabetes patient with diabetic ketoacidosis in the 8th month of pregnancy]. PMID- 4205405 TI - [The adjusted mortality rate]. PMID- 4205404 TI - [Assistance in social rehabilitation of a patient with muscular dystrophy]. PMID- 4205406 TI - [Human chromosomes. 2. Chromosome abnormalities]. PMID- 4205407 TI - [Body temperature and fever]. PMID- 4205408 TI - [Homeostasis. 2. The basic principles of feedback control]. PMID- 4205409 TI - [Transfer technic. 7. Assistance of the patient in taking a sitting position]. PMID- 4205410 TI - [Modern counseling. 2. Counseling and the every day life]. PMID- 4205411 TI - [Staff conference at the Department of Internal Medicine, Kobe Univerity Hospital. A leukemic patient who accidentally discovered the true diagnosis of his condition]. PMID- 4205412 TI - [Observation by a psychiatric nurse]. PMID- 4205413 TI - [Problems of psychiatric nursing]. PMID- 4205414 TI - [The starting point in psychiatric nursing]. PMID- 4205415 TI - [Frequency of recurrence following treatment of hyperthyroidism with methimazole and suppressibility of the thyroid gland (author's transl)]. PMID- 4205416 TI - [Clofezone, a new potent antirheumatic drug]. PMID- 4205417 TI - Hunger and satiety in humans during parenteral hyperalimentation. PMID- 4205418 TI - Identification and localization of intraarticular colloidal gold: ultrastructural and electron microprobe examinations of human biopsies. PMID- 4205419 TI - The reticulum cell and the reticular cell in the mouse popliteal lymph node. An electron microscopic autoradiographic study. PMID- 4205420 TI - Nephritogenic properties of nephrotoxic guinea pig antibodies. II. Glomerular lesions induced by F(ab')2 fragments of nephrotoxic IgG1 antibody in rats. PMID- 4205421 TI - [Cellular nucleic acid synthesis in the rat anterior pituitary gland after dexamethasone treatment (author's transl)]. PMID- 4205422 TI - [Autoradiographic studies on intralobuar differences of the influx rate of hepatocytes into S compartment at early stages after partial hepatectomy (author's transl)]. PMID- 4205423 TI - [The influence of testerone-propionate on the proliferation of the seminal vesicles epithelium in castrated rats (author's transl)]. PMID- 4205424 TI - Effect of heparin, histamine and serotonin on the density-dependent inhibition of replication in two fibroblastic cell lines. PMID- 4205425 TI - [A comparative assessment of the virulence of enterococci isolated from patients and from the intestinal contents of healthy subjects]. PMID- 4205426 TI - [Decarboxylation of lysine by cultures of Ps. aeruginosa]. PMID- 4205427 TI - [Toxic, sensitizing and immunogenic properties of antigenic complexes of brucella]. PMID- 4205428 TI - [The sensitivity of diphtheria bacteria to several antibiotics and the effect of sanitation on elimination of the agent from carriers]. PMID- 4205429 TI - [Cultural and serologic properties of type strains of meningococcus]. PMID- 4205430 TI - Letter: Rhesus prophylaxis after twin delivery. PMID- 4205431 TI - Kotonkan, a new rhabdovirus related to Mokola virus of the rabies serogroup. PMID- 4205432 TI - Infectivity of sputum-positive tuberculous patients on chemotherapy. PMID- 4205433 TI - Routine diagnosis of tuberculosis with phase-contrast microscopy. PMID- 4205434 TI - Letter: Selective inhibition of phagocytic activity of rabbit alveolar macrophages by cystic fibrosis serum. PMID- 4205435 TI - Osmium impregnation of methyl methacrylate vascular casts for scanning electron microscopy. PMID- 4205436 TI - An electron microscopic observation of the nucleolar material attached to the chromosomes of HeLa cells in metaphase. PMID- 4205437 TI - [The effect of Bacillus subtilis alpha-amylase on starch]. PMID- 4205438 TI - [Purification and properties of pectate-transeliminase acid from Clostridium felsineum]. PMID- 4205439 TI - [Effect of the peroxidation of microsomal lipids on the spectral characteristics of cytochrome P-450]. PMID- 4205440 TI - [Some characteristics of the transcription process in the chromatin of liver cells in chemical carcinogenesis]. PMID- 4205441 TI - Microbial degradation of DDT metabolites to carbon dioxide, water, and chloride. PMID- 4205442 TI - Polychlorinated terphenyls in the environment. PMID- 4205443 TI - Effects of sodium arsenite on fetal development. PMID- 4205444 TI - Chlorinated hydrocarbon residues in marine animals of southern California. PMID- 4205445 TI - Similarity of a polychlorinated biphenyl (Aroclor 1254) and DDE in rate of elimination from cows. PMID- 4205446 TI - Improved procedures for the determination of oxytetracycline in milk, milk products; chicken muscle, liver; and eggs. PMID- 4205447 TI - Discrimination between PCB and DDT residues by a gas chromatographic-mass spectrometric technique. PMID- 4205448 TI - Polychlorinated biphenyls: photolysis of 3, 4, 3', 4'-tetrachlorobiphenyl and 4, 4'-dichlorobiphenyl in solution. PMID- 4205449 TI - Acute intraperitoneal toxicity of DDT and PCB's in mice using two solvents. PMID- 4205450 TI - The malignant transformation as a metabolic steady state transition: the possible significance of the phasing of enzyme synthesis and related aspects. PMID- 4205451 TI - An investigation of the aetiology of the 1966 outbreak of febrile illness in Jabalpur, Madhya Pradesh. PMID- 4205452 TI - Preliminary studies of body potassium in normal adults by whole body counter. PMID- 4205455 TI - Use of isotopic abundance ratios in identification of polychlorinated biphenyls by mass spectrometry. PMID- 4205453 TI - Vital signs in progressive intracranial hypertension: an experimental study. PMID- 4205454 TI - Susceptibility of N. gonorrhoeae in vitro to antibiotics (penicillin, oxytetracycline, chloramphenicol and rifampicin). PMID- 4205456 TI - Antigenic properties of some insects involved in food contamination. PMID- 4205457 TI - Inhibition of lipid biosynthesis by p-chlorophenoxy-isobutyrate (CPIB) in Tetrahymena pyriformis. PMID- 4205458 TI - Studies on ion transport in cells of photosynthetic bacteria. I. The key role of anions in determining the direction and magnitude of hydrogen ion flux. PMID- 4205459 TI - Studies on ion transport in cells of photosynthetic bacteria. II. Analysis of reversed hydrogen ion change. PMID- 4205460 TI - Studies on ion transport in cells of photosynthetic bacteria. 3. The influence of uncouplers on hydrogen ion change. PMID- 4205461 TI - The characteristic action patterns of crystalline bacterial saccharifying alpha amylase independent of its microheterogeneity. PMID- 4205463 TI - Effects of ventral putamen lesions on discrimination learning by monkeys. PMID- 4205462 TI - Competition between Pi and pH indicators in photosynthetic ATP formation in chromatophores of Rhodospirillum rubrum. PMID- 4205464 TI - Carrier rate of Neisseria meningitidis and the occurrence of sulfonamide resistant strains in Lebanon. PMID- 4205465 TI - A study of passive potassium efflux from human red blood cells using ion-specific electrodes. PMID- 4205467 TI - An analysis of the relationship between the current and potential generated by a quantum of acetylcholine in muscle fibers without transverse tubules. PMID- 4205466 TI - The penetration of water into the epithelium of toad urinary bladder and its modification by oxytocin. PMID- 4205469 TI - A new myxosporidan in red and golden shiners. PMID- 4205468 TI - Effect of antiserum on maltase from intestinal microvillous membranes of Ascaris suum. PMID- 4205470 TI - An evaluation of the direct agglutination test for Chagas' disease. PMID- 4205471 TI - Significance of intimal arterial changes in non-human vertebrates. PMID- 4205472 TI - Physiologic and clinical actions of nitroglycerin. PMID- 4205473 TI - Diagnosis of angina pectoris at the present time. PMID- 4205474 TI - [Epileptic seizures in old age]. PMID- 4205475 TI - [2 cases of diverticulum of the female ureter]. PMID- 4205476 TI - Diabetes mellitus. New developments. PMID- 4205477 TI - [On some hematological complications caused by drug therapy]. PMID- 4205478 TI - [Biliary peritonitis; reference to 12 cases]. PMID- 4205479 TI - [Comparative study of the immunodiffusion and electro-immunodiffusion methods in the detection of Australia antigen]. PMID- 4205480 TI - The etiology and pathogenesis of osteoarthrosis: a review. PMID- 4205481 TI - Long-term toxicity study of methylmercuric chloride in monkeys (first report). PMID- 4205482 TI - [Problem of proteinuria]. PMID- 4205483 TI - [Relationship between the instability in saline and the competence for genetic transformation in Bacillus subtilis]. PMID- 4205484 TI - [Treatment of the acute hypercalcemic crisis]. PMID- 4205485 TI - [Radiotherapy of tumors in radiological practice]. PMID- 4205486 TI - [Cytoarchitecture of the superior colliculus of the midbrain in Cercopithecidae]. PMID- 4205488 TI - Some factors influencing TRH bioassay in mice. PMID- 4205487 TI - Competitive inhibition between oxytocin and luteinizing hormone-releasing factor (LRF) for the same enzyme system in the rat hypothalamus. PMID- 4205489 TI - Rapid estimation of human chorionic somatomammotrophin (HCS) by haemagglutination inhibition and comparison of results with radioimmunoassay. PMID- 4205490 TI - Influence of oophorectomy, luteectomy, foetal death and dexamethasone on the peripheral plasma levels of oestrogens and progesterone in the pregnant Macaca mulatta. PMID- 4205491 TI - Nitrogen-15 studies of erythropoiesis during recovery from marasmus. PMID- 4205492 TI - Vitamins A and E nutrition via intramuscular or oral route. PMID- 4205493 TI - Plasma and red cell water and elements in protein-calorie malnutrition. PMID- 4205494 TI - Effects of protein-calorie malnutrition on the jejunal mucosa of tetracycline treated pigs. PMID- 4205495 TI - Infant and child enteritis-malabsorption-malnutrition: the potential of limited studies with low-dose antibiotic feeding. PMID- 4205497 TI - Cerebral arterial occlusion and cluster headaches in neurofibromatosis. PMID- 4205496 TI - Red blood cell beta-aminolevulinic acid dehydrase activity. An index of body lead burden. PMID- 4205498 TI - Bacteraemia as a complication of subclavian vein catheterisation. PMID- 4205499 TI - Immunofluorescent studies in mucous membrane pemphigoid. PMID- 4205500 TI - Letter: Pseudomonas infections. PMID- 4205501 TI - Letter: What is meant by "bimonthly"? PMID- 4205502 TI - Letter: Gold treatment of pemphigus. PMID- 4205504 TI - Editorial: Hereditary eye disease and prenatal diagnosis. PMID- 4205503 TI - Laboratory diagnosis of increased lead absorption. PMID- 4205505 TI - Electrophysiological and psychophysical findings in Hunter syndrome. PMID- 4205506 TI - Serum levels of C1q, C1r and C1s in normal and pathologic sera. PMID- 4205508 TI - A general method for the preparation of tritiated polychlorobiphenyls of high specific activity: 2,2',5,5'-tetrachlorobiphenyl-(3H) and 2,2',4,4',5,5' hexachlorobiphenyl-(3H). PMID- 4205507 TI - Column chromatographic separation of polychlorinated biphenyls from chlorinated hydrocarbon pesticides, and their subsequent gas chromatographic quantitation in terms of derivatives. PMID- 4205509 TI - Separation of aldrin from Aroclor 1254. PMID- 4205510 TI - PCB residues in Atlantic zooplankton. PMID- 4205511 TI - Mirex residues in wild populations of the edible red crawfish (Procambarus clarki). PMID- 4205512 TI - The extended care philosophy: A must for the long-term patient. PMID- 4205513 TI - Tumor-associated antigen(s) from granulosa cell carcinomas of the ovary. PMID- 4205514 TI - Treatment of streptococcal pharyngitis with different antibiotic regimens. PMID- 4205515 TI - A survey of pulmonary tuberculosis in the elderly in North Staffordshire. PMID- 4205516 TI - Factors influencing admission and discharge from a hospital for the chronic sick in Israel. PMID- 4205517 TI - The changing pattern of geriatric care. A 20-year survey report from the West Cornwall clinical area. PMID- 4205518 TI - The cooperative health statistics system. PMID- 4205519 TI - Survey instrument to study institutional care services for convalescent and long term patients. PMID- 4205520 TI - Collaborative study of the recovery and gas chromatographic quantitation of polychlorinated biphenyls in chicken fat and polychlorinated biphenyl-DDT combinations in fish. PMID- 4205521 TI - Polychlorinated biphenyls and polychlorinated terphenyls in Canadian food packaging materials. PMID- 4205522 TI - A serum component related to nonimmunoglobulin amyloid protein AS, a possible precursor of the fibrils. AB - A nonimmunoglobulin protein with the molecular weight of 9,145 (protein AS) has been shown to be a principal component of the amyloid fibrils in different clinical types of amyloidosis. A protein component, antigenically closely related to protein AS, was detected in human sera. The protein AS-related component (protein ASC) was found in the sera of many groups of patients, including 48 out of 55 patients with various clinical types of amyloidosis. No structural relationship of protein ASC to the plasma component of amyloid was found. Protein ASC was also present with high frequency in the serum of diseases known to be frequently complicated by amyloidosis. In some cases, ASC was found in the sera of patients 2-3 yr before the diagnosis of amyloidosis was established. Protein ASC was also frequently found in hypogammaglobulinemia. Among normal individuals, protein ASC was seldom detected in the serum by our techniques, but there was a noticeable increase with age and during pregnancy. Moreover, a more sensitive technique, immunoelectro-osmophoresis, revealed protein ASC in a higher number of sera from both patients and normal controls. Thus protein ASC was suggested to be a normal serum constituent, usually present only in minor quantities. Under certain conditions, protein ASC increases considerably in serum, and may in such instances act as a precursor for the deposition of amyloid fibrils in the tissues. PMID- 4205523 TI - Disturbance of serum viscosity in diabetes mellitus. AB - The serum viscosity of diabetic patients has been found to be increased. The elevation averaged 8% above healthy subjects and 6% above nondiabetic patients. The serum viscosity elevation was greater when diabetic sequelae associated with microangiopathy were present. No relation of serum viscosity to age, sex, obesity, duration of disease, or type of treatment was demonstrated. Serum total protein and glucose levels were found to be correlated with serum viscosity, and increases in their serum concentrations were observed in diabetes. Analysis demonstrated that their elevation did not explain either the viscosity increase or the difference in viscosity between diabetics with and without sequelae.Intrinsic viscosity, abbreviated [eta], is a concentration-independent solute property related to molecular shape. [eta] was found to be 7% higher in diabetic than in normal serum. The [eta] difference accounted for at least half of the serum viscosity elevation. The rest of the increase was due to increased serum protein level and increased nonprotein solids, presumably glucose and lipid. Associated with increased [eta] was a decline in albumin: globulin ratio and elevation of the acute phase reactant proteins, alpha(1)-acid glycoprotein, alpha(1)-antitrypsin, haptoglobin, and ceruloplasmin. Studies comparing diabetic and normal serum fractionated by using 21.5% sodium sulfate showed that changes in [eta] were attributable to changes in serum protein composition rather than an inherent qualitative disturbance of protein present in one of the fractions. Since serum viscosity is elevated in early diabetes, it may be a part of the metabolic disturbance of diabetes and could play a role in the development of diabetic microangiopathy. PMID- 4205524 TI - Increased clearance of antipyrine and d-propranolol after phenobarbital treatment in the monkey. Relative contributions of enzyme induction and increased hepatic blood flow. AB - The effects of phenobarbital treatment for 12 days on the regional distribution of blood flow and on the disposition of two model drugs, antipyrine and d propranolol, have been determined in six unanesthetized rhesus monkeys. Phenobarbital significantly increased total hepatic blood flow from 179+/-15 to 239+/-27 ml/min. Liver weight was increased to a similar degree (34%) in phenobarbital-treated animals as compared to control monkeys. The clearance of both antipyrine and d-propranolol was increased and the half-life decreased significantly by phenobarbital. Analysis of the data by a perfusion-limited pharmacokinetic model showed that the changes in antipyrine clearance were due almost entirely to enzyme induction. On the other hand, with d-propranolol, the increase in liver blood flow contributed as much to the enhanced clearance as did the stimulation of drug metabolism. The mechanism by which phenobarbital produces the frequently observed increase in drug clearance, therefore, depends upon the initial clearance value of the drug. For low clearance drugs like antipyrine, clearance changes occur largely as a result of enzyme induction. With higher clearance drugs, the effects of increased hepatic blood flow become progressively more important the greater the initial clearance value. PMID- 4205526 TI - The isolation and characterization of an anti-sheep red blood cell antibody having limited heterogeneity. PMID- 4205525 TI - Local and systemic cell-mediated immunity after immunization of guinea pigs with live or killed m. tuberculosis by various routes. PMID- 4205527 TI - Characterization of the Fv fragment isolated from a human immunoglobulin M. PMID- 4205529 TI - Requirement for bone marrow-derived cells in resistance to Listeria. PMID- 4205528 TI - Antigenic studies of J chain. PMID- 4205530 TI - Changes in antigenic properties of human C3 upon activation and conversion by trypsin. PMID- 4205531 TI - Effect of polyadenine: polyuridine on brucellosis in conventional and congenitally athymic mice. PMID- 4205532 TI - Mucosal and glandular distribution of immunoglobulin components: differential localization of free and bound SC in secretory epithelial cells. PMID- 4205533 TI - Immunoglobulins with multiple binding functions. II. The use of nylon-polyserine whisker discs in screening myeloma immunoglobulins for binding activity. PMID- 4205535 TI - Trouble-free microbiologic serum and red cell folate assays. PMID- 4205534 TI - Studies of cellular immunity in Chagas disease: effect of glutaraldehyde-treated specific antigen on inhibition of leukocyte migration. PMID- 4205536 TI - Medial occipital projections to the nucleus of Darkschewitsch of rhesus monkey. PMID- 4205537 TI - Lactic dehydrogenase activity in the hair follicles of the stump-tailed macaque (Macaca speciosa). PMID- 4205539 TI - Carbaryl residues in bees, honey, and bee bread following exposure to carbaryl via the food supply. PMID- 4205540 TI - [Chromosome loss following x-ray irradiation of mature oocytes from Drosophila melanogaster]. PMID- 4205538 TI - PCB levels in egg yolks associated with embryonic mortality and deformity of hatched chicks. PMID- 4205541 TI - [Mamillo-cortical pathways of the brain]. PMID- 4205542 TI - [Pharmacological and toxicological principles of research on drugs in man]. PMID- 4205543 TI - [Phase I studies on healthy test subjects and patients]. PMID- 4205544 TI - [Pharmacological aspects of comparative studies on different blood sugar-lowering sulfonylureas]. PMID- 4205545 TI - Spontaneous awake EEG patterns in three lines of primate evolution. PMID- 4205546 TI - Interocular transfer of mirror image discriminations by chiasm-sectioned monkeys. PMID- 4205547 TI - Loss of social group affinity following prefrontal lesions in free-ranging macaques. PMID- 4205548 TI - Concerning the influence of experimental conditions on social interactions initiated by telestimulation in squirrel monkey groups. PMID- 4205549 TI - Interocular reversal of preference for lateral mirror-image shapes by the monkey with sectioned optic chiasm. PMID- 4205550 TI - Control of catabolism of mitochondria in oncogenesis. I. Increase of hepatic mitochondrial population during feeding inactive or marginally active amino azo dyes: absence of de novo biosynthesis. PMID- 4205551 TI - On the sensitivity of pseudomonas and proteus to the combination of trimethoprim and sulphamethoxazole. PMID- 4205552 TI - Follow-up of a group of workers exposed to dusts containing derivatives of Bacillus subtilis. PMID- 4205554 TI - Farmer's lung: a comparison of simple diagnostic techniques and antigen preparation in human and bovine disease. PMID- 4205553 TI - Clinical and immunological responses to enzymes of Bacillus subtilis in factory workers and consumers. PMID- 4205555 TI - The anatomy of the mitochondrial DNA. The localization of the heat-induced and RNAase-induced scissions in the phosphodiester backbones. PMID- 4205556 TI - Mutants of Bacillus subtilis blocked in acetoin reductase. PMID- 4205557 TI - Active subunits of transaldolase bound to sepharose. PMID- 4205558 TI - Comparison of the suppressive effect of thymus cells and the suppression by neonatal application of antigen. PMID- 4205559 TI - Antibodies specific for human T lymphocytes in cold agglutinin and lymphocytotoxic sera. PMID- 4205560 TI - Seasonal and hormonally induced changes in the serum level of the precursor protein vitellogenin in relation to ovarian vitellogenic growth in the toad Bufo bufo bufo (L.). PMID- 4205561 TI - The effect of lesions in the centromedian nucleus of the thalamus on the monkey's performance in delayed alternation and object reversal tasks. PMID- 4205562 TI - Muscle AMP aminohydrolase. X. Effect of anions on the kinetic and regulatory properties of the rat muscle enzyme. PMID- 4205563 TI - Interrelationships in the regulation of TSH and prolactin secretion in man: effects of L-dopa, TRH and thyroid hormone in various combinations. PMID- 4205564 TI - The effect of an ethanol-extractable thyroxine binding substance in plasma on the measurement of thyroxine by competitive binding. PMID- 4205565 TI - Progesterone-binding protein in human myometrium. Influence of metal ions on binding. PMID- 4205566 TI - Late hemispherectomy complications. Unilateral hydrocephalus from aqueductal obstruction. PMID- 4205567 TI - Participation of medial pontine reticular formation in eye movement generation in monkey. PMID- 4205568 TI - Responses of primate spinothalamic tract neurons to natural stimulation of hindlimb. PMID- 4205569 TI - Precentral and postcentral cortical activity in association with visually triggered movement. PMID- 4205570 TI - [Effect of nitroglycerine and its derivatives on the cerebral circulation in patients with ischemic heart disease (according to the data of the clinico angioretinophotometric studies)]. PMID- 4205571 TI - [Electrophysiological characteristics of the isolated heart in a heart-lung preparation]. PMID- 4205572 TI - Scanning of the apical pole of distal tubular cells under differing acid-base conditions. PMID- 4205573 TI - [Treatment of bronchial asthma at home and in hospital (author's transl)]. PMID- 4205574 TI - [Blood sugar and plasma lipids in fasting diabetics and in metabolically healthy subjects (author's transl)]. PMID- 4205575 TI - [Measurement of renal blood flow with radionuclides (author's transl)]. PMID- 4205576 TI - [Benzylamines and their homologues in the treatment of diseases of the ear, nose and throat (author's transl)]. PMID- 4205577 TI - [Glucagon for the treatment of pancreatitis]. PMID- 4205578 TI - Catheter complications in total parenteral nutrition. A prospective study of 200 consecutive patients. PMID- 4205579 TI - Zen macrobiotic dietary problems in infancy. PMID- 4205580 TI - Serum aldosterone concentrations related to sodium balance in the newborn infant. PMID- 4205581 TI - Visceral neurofibromatosis and hypertension in childhood. PMID- 4205582 TI - Neonatal gonococcal arthritis: three cases and review of the literature. PMID- 4205583 TI - Chelation therapy in children with subclinical plumbism. PMID- 4205584 TI - Acetylcholinesterase from a non-membrane source (Bungarus fasciatus venom). PMID- 4205585 TI - Alcoholism and animals. PMID- 4205586 TI - Smallpox vaccination and its consequences: first experiences with the highly attenuated smallpox vaccine "MVA". PMID- 4205587 TI - [Sensitization to the Kidd IKa blood group factor]. PMID- 4205588 TI - [Immunization of volunteer donors to obtain large amounts of active antirhesus sera]. PMID- 4205589 TI - [Micromethod for determining the rhesus factor]. PMID- 4205590 TI - [Use of the albumin from fibrinolyzed blood in producing sera for determining the rhesus factor by an express method]. PMID- 4205591 TI - Calcium-induced extrusion of secretory granules (exocytosis) in mast cells exposed to 48-80 or the ionophores A-23187 and X-537A. AB - Isolated peritoneal mast cells from rats were observed, by phase contrast microscopy, to extrude secretory granules when exposed to 48/80 or the ionophores A-23187 and X-537A, which are known to facilitate transmembrane fluxes of calcium. These effects were abolished when the cells were treated with EDTA and suspended in a Ca-free environment. Ca-deprived cells exposed to any one of the three drugs promptly extruded granules when calcium, but not magnesium, was added to the incubation medium. Such Ca-evoked or Ca-dependent responses persisted when Na was omitted from the incubation medium and replaced with sucrose, choline, or K. The responses thus seem independent of possible shifts in the alkali metal ions. The results are considered support for the view that Ca influx mediates stimulus-secretion coupling and does so by initiating exocytosis. PMID- 4205592 TI - A comparison of bovine prothrombin, factor IX (Christmas factor), and factor X (Stuart factor). AB - A comparison has been made of the electrophoretic behavior, chemical composition, amino-terminal sequence, and immunological properties of bovine prothrombin, factor IX (Christmas factor), and factor X (Stuart factor). Some immunological crossreactivity was found between the antibody to prothrombin and factor X although prothrombin and factor X differ substantially in amino-acid and carbohydrate composition. Considerable amino-acid sequence homology was found in the amino-terminal portion of prothrombin, factor IX, and the light chain of factor X. These data provide further evidence to support the hypothesis that at least three of the vitamin K-dependent clotting factors have evolved from a common ancestral gene. PMID- 4205593 TI - In vitro synthesis of ribosomal proteins directed by Escherichia coli DNA. AB - In vitro synthesis of a number of E. coli 30S ribosomal proteins has been demonstrated in a cell-free system consisting of ribosomes, initiation factors, RNA polymerase, a fraction containing soluble enzymes and factors, and E. coli DNA. DNA-dependent synthesis of the following 30S proteins has been demonstrated: S4, S5, S7, S8, S9, S10, S13, S14, S16, S19, and S20. PMID- 4205594 TI - Chemotactic activity in dialyzable transfer factor. AB - Dialyzable transfer factor from human leukocytes was found to be strongly chemotactic for granulocytes and weakly chemotactic for monocytes in vitro. Chemotactic properties were also demonstrated in vivo in rhesus monkey skin. Initial purification of the dialyzable transfer factor by Sephadex G-25 chromatography revealed multiple fractions containing material with 255-nm absorbance. The fractions containing chemotactic activity were also capable of transferring delayed hypersensitivity to rhesus monkeys. This chemotactic material has an apparent molecular weight of 5000 daltons or less and was not inactivated by goat antibody to components C3 or C5 of human complement; chemotactic activity was lost after storage for two weeks at 4 degrees and the activity of two of three preparations was decreased by heating for 30 min at 56 degrees . This previously undescribed chemotactic activity of dialyzable transfer factor may have significance in relation to cell-mediated immune responses. PMID- 4205595 TI - Immunostimulation with bacterial phospholipid extracts. AB - Injection of bacterial phospholipid extracts (EBP) into mice increased their resistance towards a Listeria monocytogenes infection. The blood clearance of virulent Salmonella typhimurium was enhanced and the degree of clearance correlated with the dose of extract injected. The multiplication of Listeria monocytogenes in spleen and liver of mice was inhibited and this inhibition was also correlated with the amount of extract injected. The absence of apparent toxicity in mice, of splenoand hepatomegaly, and of lymphoid hyperplasia, distinguish this immunostimulant from other known bacterial stimulants of host resistance to infection. PMID- 4205596 TI - Toxigenic algae. PMID- 4205597 TI - Role of prostaglandins in estrogen-induced uterine hyperemia. PMID- 4205598 TI - Inability of prostaglandin synthesis inhibitors to affect adipose tissue lipolysis. PMID- 4205599 TI - Specific binding sites in the rabbit kidney for prostaglandin A. PMID- 4205600 TI - [Treatment of pharyngeal neoplasms with electromagnetic betatron radiation with 25 Mev. energy]. PMID- 4205601 TI - [Toxicological studies of enzymatic preparations intended for use in the food industry]. PMID- 4205602 TI - Increased forearm venous compliance during exercise with nitroglycerin. PMID- 4205603 TI - The estimation of molecular weight of tonofilaments by gel-filtration in 6M guanidine hydrochloride and by sodium dodecylsulfate acrylamide gel electrophoresis. PMID- 4205604 TI - Insulin deficiency and hyperosmolar coma. PMID- 4205605 TI - Gonococcal infection. Clinical, epidemiologic and laboratory perspectives. PMID- 4205606 TI - Thyrotropin-releasing hormone. PMID- 4205607 TI - [Immunohematologic organization in a maternity department]. PMID- 4205608 TI - [Formation of DL-lactic acid by lactobacilli and characterization of a lactic acid racemase from several streptobacteria (author's transl)]. PMID- 4205609 TI - [The morphogenesis and histological classification of nevocellular nevuses]. PMID- 4205610 TI - [Rates of interaction of adrenolytics with smooth muscle alpha-adrenoreceptors]. PMID- 4205612 TI - A contribution to the solitary ciliogenesis. PMID- 4205611 TI - Polychlorinated biphenyl-induced decrease in liver vitamin A in Japanese quail and rats. PMID- 4205613 TI - Contribution to study of the arterial supply of the gastrointestinal tract of the toad (Bufo bufo). PMID- 4205614 TI - [Calibration and experiences in the use of whole body counter as a measuring device of internal and external contaminations]. PMID- 4205615 TI - [Substenosing intestinal tuberculosis]. PMID- 4205616 TI - [Isotopic hormone blood level]. PMID- 4205617 TI - [Total intravenous feeding in infants]. PMID- 4205618 TI - Macroglobulin-producing histiocytic lymphoma of hepatic origin. PMID- 4205619 TI - [Sciatica due to lumbar chondroma (author's transl)]. PMID- 4205621 TI - [Simultaneous determination of serum copper and iron]. PMID- 4205620 TI - [Drug therapy of the nerve-root-irritation syndrome]. PMID- 4205622 TI - [Advances in the treatment of bone defects (author's transl)]. PMID- 4205623 TI - [The surgical dressing of fractures of the ankle joint with the small fragment instrumentarium (AO) (author's transl)]. PMID- 4205624 TI - [Primum nil nocere. Is operative risk particularly great in rheumatics? (author's transl)]. PMID- 4205625 TI - [Epidemiological studies of pseudomonas hospitalism (author's transl)]. PMID- 4205627 TI - Residues of mirex and certain other chlorinated hydrocarbon insecticides in beef fat--1971. PMID- 4205629 TI - Perforated jejunal diverticulum diagnosed as acute appendicitis. PMID- 4205630 TI - Osteochondritis dissecans of the talus. PMID- 4205631 TI - Neurological sequelae of decompression in supersonic transport aircraft. PMID- 4205632 TI - [Plasma amino acid pattern in parenteral nutrition with different amino acid solutions (author's transl)]. PMID- 4205633 TI - Specific impairment of host defense for pseudomonas infection in mice by a burn toxin derived from thermally altered human skin. PMID- 4205634 TI - [Value of pyrazinobutazone in long term treatment of chronic pain syndromes in the aged]. PMID- 4205635 TI - The unilateral engram. AB - It is proposed that the corpus callosum has a major role in the processes of memory; first, by providing access by each hemisphere to memory traces stored in the other, and second, by controlling the formation of memory traces in such a way that they are laid down in only one hemisphere instead of in both. This dual mechanism would have the effect of doubling the mnemonic storage capacity of the brain. Evidence in favor of this hypothesis in briefly reviewed. It is also supported by experiments using electrical excitation of the striate cortex as a conditional stimulus in macaques, and by experiments on maze behavior in the m e species. Experiments with the anterior commissure, on the other hand, show that it, in contrast to the splenium of the corpus callosum, can actually transfer an engram from one hemisphere to the other. Finally, it is shown that the splenium provides an effective path of communication between the central visual system in one hemisphere and the amygdala in the other. PMID- 4205636 TI - Some characteristics of self-stimulation behavior of dogs. AB - Self-stimulation was studied in dogs chronically implanted with electrodes in different points within the basal forebrain. The animals exhibiting pure self rewarding behavior were defined as "optimal" and "good self-stimulators", whereas those with concomitant aversive phenomena were incorporated into the third category called "self-stimulation-withdrawal". In "optimal self-stimulators" a remarkable resistance of the response to extinction was noted. A strong negative attitude toward food was found in four dogs upon stimulation of the self rewarding loci. Penile erection accompanied self-stimulation in two animals. Sniffing at first always followed incentive brain stimulation, but later it appeared at the beginning of each experiment and/or preceded the bouts of pressing. A rise of hypothalamic temperature was noted in mast of the animals. In some cases this was equal to or exceeded 1 degree Celsius. The temperature increase was accompanied by intense panting between the bouts. Seizures appeared locally as contractions of masticatory muscles and sometimes developed into a generalized fit. Anatomically the "reward area" in the dog extends from the septum and the preoptic area to the mammillary bodies and reaches laterally to the internal capsule. PMID- 4205637 TI - Analysis of the polychlorinated biphenyl problem. Application of gas chromatography-mass spectrometry with computer controlled repetitive data acquisition from selected specific lons. PMID- 4205639 TI - Demonstration of nuclear and cytoplasmic fluorescence in brain tissues of schizophrenic and nonschizophrenic patients. PMID- 4205638 TI - [Biometric studies elucidating the pathogenesis of arthrosis exemplified by the ankle joint (author's transl)]. PMID- 4205640 TI - Gonococcal vaccine studies in Inuvik. PMID- 4205641 TI - Health services for foster children: an evaluation of agency programs. PMID- 4205643 TI - Antidepressant effect of thyrotropin-releasing hormone (TRH) and the plasma thyrotropin levels in depression. PMID- 4205644 TI - Clinical and social aspects of a non-geriatric long-stay psychiatric unit. PMID- 4205642 TI - L-glutamate decarboxylase and choline acetyltransferase activity in the substantia nigra and the striatum after surgical interruption of the strio-nigral fibres of the baboon. PMID- 4205645 TI - Timing of meiotic crossing-over in Drosophila melanogaster. PMID- 4205646 TI - Effects of cadmium on development time and prepupal puffing pattern of Drosophila melanogaster. PMID- 4205647 TI - A chlorine-free embedding medium for use in x-ray analytical electron microscope localisation of chloride in biological tissues. PMID- 4205648 TI - The effects of different preparative procedures on the ultrastructure of the hamster ovary. I. Effects of various fixative solutions on ovarian oocytes and their granulosa cells. PMID- 4205649 TI - Functional radioisotope investigations in chronic nephritis. PMID- 4205650 TI - Maridomycin, a new macrolide antibiotic. I. Taxonomy and fermentation. PMID- 4205651 TI - Study on in vitro activity of the antibiotics tobramycin and gentamicin against Pseudomonas aeruginosa clinical strains. PMID- 4205652 TI - Aminoglycoside antibiotics. IV. BU-1709 E1 and E2, new aminoglycoside antibiotics related to the butirosins. PMID- 4205653 TI - Isolation and characterization of the methionine antagonist L-2-amino-4-methoxy trans-3-butenoic acid from Pseudomonas aeruginosa grown on n-paraffin. PMID- 4205654 TI - Bias functions and operating characteristics of rats discriminating auditory stimuli. AB - Rats were trained to discriminate between two bursts of random noise that differed in intensity. In a two-lever, discrete-trial procedure, correct responses were reinforced with brain stimulation, and incorrect responses produced timeout. Responding was studied as a function of the decibel difference between the stimuli, the probabilities of presenting the stimuli, the relative duration of timeout consequent upon the two types of incorrect responses, and the absolute duration of timeout consequent upon incorrect responses. The results showed that the distribution of responses between the two levers depended upon the stimulus probabilities, but were independent of either the absolute or relative durations of timeout. When the stimulus probabilities were varied, the response probabilities did not match the stimulus probabilities; when the relative durations of timeout were varied, the animals did not obtain the maximum rate of reinforcement per unit time. Instead, the animals distributed their responses so as to obtain the maximum number of reinforcements at each level of discrimination. In addition, the level of discrimination increased as a function of the decibel difference between the stimuli. PMID- 4205655 TI - [Studies on the combination action of synthetic penicillins, hetacillin and dicloxacillin (author's transl)]. PMID- 4205656 TI - [Laboratory and clinical studies on josamycintartrate injection in chest surgery (author's transl)]. PMID- 4205657 TI - Basic studies on 3', 4'-dideoxykanamycin B. PMID- 4205658 TI - Monkeys agree-noise is upsetting. PMID- 4205659 TI - Role of a myocardial depressant factor in shock states. PMID- 4205660 TI - The case history of monkey no. 109: first experimentally produced vertical gaze palsy. PMID- 4205661 TI - Potential changes associated with eye movements in the thalamus, visual cortex and reticular formation. PMID- 4205662 TI - Thermal degradation of some parenteral solutions of reserpine. 2. Effects of ionic strength, dielectric constant, inert gas and stabilizers. PMID- 4205663 TI - [Antigenic structure of Histoplasma farciminosum. 3. Double-diffusion in agar gel and immunoelectrophoresis]. PMID- 4205664 TI - [Immunoelectrophoretic pattern of serum proteins in Rh-negative women receiving prophylactically anti-Rh (D) immunoglobulin following labor]. PMID- 4205665 TI - [Comparative study of the properties of transaminases in different types of Mycobacterium tuberculosis]. PMID- 4205667 TI - [Results of complex therapy of patients after early detection of destructive pulmonary tuberculosis]. PMID- 4205666 TI - [Activity of the second-line preparations, ethambutol and rifampin, in experimental tuberculosis caused by Mycobacterium tuberculosis highly resistant to basic tuberculostatics]. PMID- 4205668 TI - [Survival of Mycobacterium tuberculosis in the drop-phase of aerosol]. PMID- 4205670 TI - [Does team care give better patient care? Research starting in Lidingo hospital]. PMID- 4205669 TI - [Typing of Corynebacterium diphtheriae by means of bacteriophages in epidemiological studies of diplitheria]. PMID- 4205672 TI - [The ultrastructure of the subpellicular fibrillar structures of the infusorium Lacrymaria olor]. PMID- 4205671 TI - [The incidence of Listeria monocytogenes in slaughtered pigs (author's transl)]. PMID- 4205674 TI - [Induced convulsions. Stress cramps]. PMID- 4205673 TI - [Marker chromosome associations in monkeys. II. Association frequency and a quantitative analysis of the nucleoli in a lymphocyte culture before and after the administration of antilymphocytic immunoglobulin to the monkeys]. PMID- 4205675 TI - [Therapeutic effectiveness of methicillin in the treatment of gonorrhea in men]. PMID- 4205676 TI - [Gyrodactylus rasini n. sp. (Monogenoidea: Gyrodactylidae), a parasite of the gills of Xiphophorus helleri bred as aquarium fish in CSSR (Czechoslovakia)]. PMID- 4205677 TI - [Catalase activity of M. avium and non-chromogenous Mycobacteria of the intermediate group]. PMID- 4205678 TI - [Tuberculosis in free-living birds in the environment of tuberculosis-infected poultry farms]. PMID- 4205679 TI - [Sources and causes of the origin of avian tuberculosis in cattle in the district after elimination of bovine tuberculosis]. PMID- 4205680 TI - [Bovine tuberculosis in minks]. PMID- 4205681 TI - [Enriched nutrient medium for the production of a mixed Propionibacterium Lactobacillus acidophilus bouillon culture]. PMID- 4205682 TI - [Formation of incomplete antibodies to the administration of 2 antigens]. PMID- 4205683 TI - [Penetration of fixed virus into the brain in the vaccination of dogs]. PMID- 4205684 TI - [Developmental cycle of Sarcocystis tenella]. PMID- 4205685 TI - [Dynamic examination of the parathyroid gland with EDTA-disodium]. PMID- 4205686 TI - Birth order and parental experience in monkeys and man. PMID- 4205687 TI - Biochemistry of natural proteinase inhibitors. PMID- 4205688 TI - Biological control of mosquito larvae. PMID- 4205689 TI - Courtship behavior in Drosophila. PMID- 4205690 TI - Animal learning. Visceral and autonomic conditioning. PMID- 4205691 TI - Spatial vision. PMID- 4205692 TI - Somesthesis. PMID- 4205693 TI - Brain function: changing ideas on the role of sensory, motor, and association cortex in behavior. PMID- 4205694 TI - [On the bactericidal power of samples of human blood against strains of Brucella melitensis and Brucella abortus]. PMID- 4205695 TI - Coccidioidomycosis in a baboon recently imported from California. PMID- 4205696 TI - [Effect of antilymphocyte serum on the lymphocytic blastogenesis in vitro]. PMID- 4205697 TI - [Traumatic intracerebral haematoma (author's transl)]. PMID- 4205698 TI - [Serum-dependent defects of function of granulocytes (author's transl)]. PMID- 4205700 TI - On the macromolecular composition of the jelly coat from Strongylocentrotus purpuratus eggs. PMID- 4205699 TI - Intracellular location of newly synthesized growth hormone. PMID- 4205701 TI - Macrophage spreading in vitro. II. Manganese and other metals as inducers or as co-factors for induced spreading. PMID- 4205702 TI - A radioimmunoassay for myosin in cultured skeletal muscle cells. PMID- 4205703 TI - [Evolution of the plastid system of ethiolated Euglena gracilis in darkness following light stimulation]. PMID- 4205704 TI - [Candida septicemia due to intravenous catheters]. PMID- 4205705 TI - [Intravenous hyperalimentation in infants with prolonged diarrhea and malnutrition]. PMID- 4205706 TI - [Proceedings: II. Pyocyaneus infection. a. Prevention and therapy. Significance of Bacterium pyocyaneum (Ps. aeruginosa) from the bacteriologic viewpoint]. PMID- 4205707 TI - [Proceedings: Prevention of the Pyocyaneus infections]. PMID- 4205708 TI - [Proceedings: II. Pyocyaneus infection. c. Osteomyelitis]. PMID- 4205709 TI - [Proceedings: Autoantibody demonstration in post-traumatic osteomyelitis]. PMID- 4205710 TI - [Proceedings: V. Traffic medicine. a. Osteoporosis and traffic ability]. PMID- 4205711 TI - Effect of beta-mercaptoethanol on the binary fission in Spirotomum ambiguum Mull Ehrbg. PMID- 4205712 TI - The role of wounds in the epidemiology of nosocomial infections due to Pseudomonas aeruginosa. PMID- 4205713 TI - Comparable bactericidal activity of two chemosterilizers. PMID- 4205715 TI - Effect of microbial interactions on in vitro plaque formation by Streptococcus mutans. PMID- 4205714 TI - Radiographic cephalometric method of assessment of craniofacial growth in monkeys. PMID- 4205716 TI - Electron probe microanalysis of human enamel microstructure. PMID- 4205717 TI - Gene control of soluble protein levels during development of abnormal abdomen in Drosophila. PMID- 4205718 TI - Editorial: Trimethoprim-sulfamethoxazole (TMP-SMZ)--better late than never. PMID- 4205719 TI - [Urinary secretory IgA in lower urinary tract diseases (author's transl)]. PMID- 4205720 TI - [Studies on bactericidal activity and fading of povidone-iodine (Isodine) (author's transl)]. PMID- 4205721 TI - A study on the effects of ibuprofen on the metabolism of antipyrine in man. PMID- 4205722 TI - Cannabis and reverse tolerance: pharmacological entity or psychological phenomenon? PMID- 4205723 TI - Letter: Intal in refractory asthmatic paediatric cases. PMID- 4205724 TI - [Microsporidosis in natural populations of cockroaches, Blattella germanica L. and Blatta orientalis L]. PMID- 4205725 TI - [Effect of hydrogen ions on Bacillus megaterium reproducing in a chemostat]. PMID- 4205726 TI - [Membranous structures of Bacillus subtilis cells revealed by a negative contrast method]. PMID- 4205727 TI - [Effect of polyploidogenic substances on the morphology of Mycobacterium rubrum]. PMID- 4205728 TI - [Carbon dioxide fixation on 3-carbon acceptors in extracts of Hydrogenomonas pantotropha and Methylosinus trichosporium]. PMID- 4205729 TI - [Some characteristics of the behavior of the blue-green alga Anabaena variabilis under conditions of darkness]. PMID- 4205730 TI - [Comparative study of nitrogen fixation in purple bacteria]. PMID- 4205731 TI - An evaluation of EDTA in endodontics. PMID- 4205732 TI - [Preparation of sputum for the demonstration of tubercle bacilli in cultures and animal tests (author's transl)]. PMID- 4205733 TI - Medicolegal blood grouping tests (parentage exclusion tests). PMID- 4205734 TI - Clinical microbiology of unusual Pseudomonas species. PMID- 4205735 TI - [On 3 cases of familial epilepsy]. PMID- 4205736 TI - [Catamnestic study of a series of cases of infantile epilepsy in relation to treatment with ethosuccinimide]. PMID- 4205738 TI - Immunodiffusion studies on some Proteus strains. PMID- 4205737 TI - [Results of study of the sensitivity of gonococci to combinations of certain antibiotics]. PMID- 4205739 TI - The significance of Australia-antibody in blood donors. Study of liver histology in donors and post-transfusion hepatitis in recipients. PMID- 4205740 TI - New electrophoretic information on the surface composition of the rat erythrocyte. PMID- 4205741 TI - Bacillus megaterium, KM beta-galactosidase: purification by affinity chromatography and characterization of the active species. PMID- 4205742 TI - Bacteriophage-coded thymidylate synthetase. Evidence that the T4 enzyme is a capsid protein. PMID- 4205743 TI - Alpha-L-iduronidase activity in cultured skin fibroblasts and amniotic fluid cells. PMID- 4205744 TI - [Ultrastructure of mitosis blocked by chloral hydrate in the dividing egg of Pleurodeles waltlii Michah]. PMID- 4205745 TI - [Short term effects of a partially hydrogenated herring oil on the total lipids of the heart and liver in the weaned rat]. PMID- 4205746 TI - [Primordial red cells and congenital amputation in rabbit fetuses bearing the br gene]. PMID- 4205747 TI - [Distribution of fluorine in the different tissue of polluted needles of Abies alba]. PMID- 4205748 TI - Computational methods in beam therapy planning. PMID- 4205749 TI - EXTDOS 71. Revised and expanded version of EXTDOS, a program for treatment planning in external beam therapy. PMID- 4205750 TI - A versatile system for three-dimensional radiation dose computation and display, RTP. PMID- 4205751 TI - Program IRREG-calculation of dose from irregularly shaped radiation beams. PMID- 4205752 TI - National Cancer Center radiotherapy computer system. PMID- 4205753 TI - A computer program for optimised stationary beam treatment planning using score functions. PMID- 4205754 TI - Gram-negative infections in the ICU. PMID- 4205755 TI - Relative performance of selected toxigenic and non-toxigenic isolates of Aspergillus flavus Link ex Fries on different culture media. PMID- 4205756 TI - Uterine bleeding in rhesus monkeys after insertion of polyethylene and copper containing polyethylene intrauterine contraceptive devices. PMID- 4205757 TI - Antigenic relationship between ruminant serum proteins. PMID- 4205758 TI - Studies on antiviral property of fruiting Myxobacteria (Myxococcus virescens). PMID- 4205759 TI - The primary structures of alpha and beta chains of adult hemoglobin of the Japanese monkey (Macata fuscata fuscata). Biochemical studies on hemoglobins and myoglobins. XI. PMID- 4205760 TI - The primary structures of the alpha and beta polypeptide chains of adult hemoglobin of the Hanumam langur (Presbytis entellus). PMID- 4205761 TI - Chemical modification of neutral subtilopeptidase by aromatic diazo compounds. PMID- 4205762 TI - Letter: Pure-tone thresholds of the squirrel monkey (Saimiri sciureus). PMID- 4205763 TI - Isolation and properties of mutants of the FP2 sex factor of Pseudomonas aeruginosa. PMID- 4205765 TI - The genetic analysis of the direct and correlated response to selection for chaetae in Drosophila melanogaster. PMID- 4205764 TI - Studies related to penicillins. XI. Mechanism of degradation of benzylpenicillinic and phenoxymethylpenicillinic acid by mercury(II) acetate. PMID- 4205766 TI - Genetic and environmental control of a continuous trait, abnormal abdomen, in Drosophila melanogaster. PMID- 4205767 TI - Genetic differences between populations of Drosophila melanogaster for a quantitative trait. I. Laboratory populations. PMID- 4205768 TI - Genetic differences between populations of Drosophila melanogaster for a quantitative trait. II. Wild and laboratory populations. PMID- 4205769 TI - Isozyme mutation rate in mutator stock of Drosophila melanogaster. PMID- 4205770 TI - Acute urethritis in male college students. PMID- 4205772 TI - [X-ray diagnosis and symptoms of Zenker's diverticulum]. PMID- 4205773 TI - [Bloch-Sulzberger's ectodermal dysplasia sc. incontinentia pigmenti]. PMID- 4205771 TI - The effect of peroxidized arachidonic acid upon human platelet aggregation. PMID- 4205774 TI - Evocation of a biphasic febrile response in the rhesus monkey by intracerebral injection of bacterial endotoxins. PMID- 4205775 TI - No one told me to. PMID- 4205777 TI - [Treatment of complicated fractures of the ankles]. PMID- 4205776 TI - [Long-term results of operative treatment of fractures of the ankle with injuries to the distal tibiofibular articulation]. PMID- 4205778 TI - [Reposition technic in fractures of the talocrural region]. PMID- 4205779 TI - [Pneumoarthrography in injury of the burso-ligamental apparatus of the talocrural joint]. PMID- 4205780 TI - [Diagnosis of closed injuries of burso-ligamental apparatus of the talocrural joint]. PMID- 4205781 TI - [Our experience in the use of plasma substitutes in pediatric practice]. PMID- 4205782 TI - Intestinal microbial flora and proteolytic activity of intestinal contents. PMID- 4205783 TI - [Bacteriological problems of hemodialysis]. PMID- 4205784 TI - [Comparative ultrastructure of representatives of the genus Neisseria]. PMID- 4205785 TI - [Preparation of purified staphylococcal enterotoxin A]. PMID- 4205786 TI - [Antigens of nephritogenic types of group A streptococci]. PMID- 4205787 TI - [Studies of the strains of N. meningitidis isolated in Belgium from 1969 to 1973]. PMID- 4205788 TI - [Comparative study of tobramycin and gentamicin]. PMID- 4205789 TI - Amniotic fluid, epinephrine, and norepinephrine. I. Comparison between the human and baboon. PMID- 4205790 TI - Letter: Intrapartum sedation of fetus. PMID- 4205791 TI - Letter: Intrapartum sedation of fetus. PMID- 4205792 TI - Ketamine and epilepsy. PMID- 4205793 TI - Gonococcal conjunctivitis. PMID- 4205794 TI - Insulin response in patients receiving concentrated infusions of glucose and casein hydrolysate for complete parenteral nutrition. PMID- 4205795 TI - The effects of short-term steroid therapy on lung bacterial clearance and survival in rats. PMID- 4205796 TI - Total intravenous feeding of infants and children without use of a central venous catheter. PMID- 4205797 TI - New techniques for long-term intravenous feeding: an artificial gut in 75 patients. PMID- 4205798 TI - Studies on the growth of Thiobacillus ferrooxidans. II. Toxicity of uranium to growing cultures and tolerance conferred by mutation, other metal cations and EDTA. PMID- 4205799 TI - Proceedings: Intravenous hyperalimentation in the treatment of inflammatory diseases of the bowel. PMID- 4205800 TI - Dihydrogenated alkaloids of ergot in geriatric patients: symptomatic treatment of cerebrovascular insufficiency. PMID- 4205801 TI - [Pattern of protein selectivity in renal diseases]. PMID- 4205802 TI - [Mutagenic effect of fluothane]. PMID- 4205803 TI - X-ray analysis of retinal photoreceptor structure. PMID- 4205804 TI - An analysis of the absorption and circular dichroism of some visual pigments. PMID- 4205805 TI - Serum immunoglobulin levels in women using intrauterine contraceptive devices. PMID- 4205806 TI - Letter: Differentiation of coccidia in cats and transmission of toxoplasmosis. PMID- 4205807 TI - [The effect of gentamicin and other antibiotics on the pathogenic germs in urinary tract infections (author's transl)]. PMID- 4205808 TI - Modulation of hypothalamic ICSS by concurrent limbic stimulation. PMID- 4205809 TI - Congenital anterior urethral diverticulum in the male. PMID- 4205810 TI - Geometric penumbra calculations for a gas target neutron source. PMID- 4205811 TI - X radiation and sensitized lymphocyte migration. PMID- 4205812 TI - Combined cytolytic effect of x irradiation and cell-mediated immune reactions on tumor cells in vitro. PMID- 4205813 TI - Oxygen cycles and metabolic autoregulation. PMID- 4205814 TI - The effect of graded hypocapnia and hypercapnia on regional cerebral blood flow and cerebral vessel caliber in the rhesus monkey: study of cerebral hemodynamics following subarachnoid hemorrhage and traumatic internal carotid spasm. PMID- 4205815 TI - Carcinoembryonic antigen in patients with squamous cell carcinoma of the cervix uteri and vulva. PMID- 4205816 TI - Mapping of behavior in Drosophila mosaics. PMID- 4205817 TI - Control of the differentiated state in somatic cell hybrids. PMID- 4205818 TI - Genetics of sperm development in Drosophila. PMID- 4205819 TI - [Various aspects of 1,2-propanediol and 1,3-butanediol metabolism following parenteral administration combined with glucose and sorbitol (experimental study)]. PMID- 4205820 TI - [The effects of staphylococcal enterotoxins on the body and their mechanism of action (review of the literature)]. PMID- 4205821 TI - [Aerosol-therapy in the chronic bronchitic syndrome]. PMID- 4205822 TI - Determination of regional myocardial blood flow (MBF) in patients with anginal pain. PMID- 4205823 TI - Serial scintigrams in the course of ectopic bone formation in paraplegic patients. PMID- 4205824 TI - Cobalt 60 treatment field verification by xeroradiography. PMID- 4205825 TI - Percentage depth dose for high energy x-ray beams in radiotherapy. PMID- 4205831 TI - Reduced sulphation factor in undernourished children. PMID- 4205833 TI - Massive gastrointestinal bleeding. A panel by correspondence. PMID- 4205832 TI - Serum C3 levels in acute glomerulonephritis and postnephritic children. PMID- 4205834 TI - Adrenal steroids in the treatment of malignant hematologic disease. PMID- 4205835 TI - Human prolactin in clinical endocrinology: the impact of radioimmunoassays. PMID- 4205836 TI - Megavoltage radiation therapy for supraglottic carcinoma. Results of treatment. PMID- 4205837 TI - Radiation dosimetry for large, irregularly-shaped fields in the treatment of acute lymphocytic leukemia. PMID- 4205838 TI - Effect of various atomic number absorbers on skin dose for 10-MeV x rays. PMID- 4205839 TI - Pseudomonas osteomyelitis. Radiologic features. PMID- 4205840 TI - [Cerebrospinal fluid in glue-induced polyneuropathies]. PMID- 4205841 TI - Chronic overdrive pacing in the control of refractory ventricular arrhythmias. PMID- 4205842 TI - Letter: Bacillus cereus endocarditis in an addict. PMID- 4205843 TI - [Use of a bundle of electrons in the radiotherapy of cervix carcinoma during pregnancy]. PMID- 4205844 TI - Phase IV final health regulations. Commentary and background material as provided by the Cost of Living Council. PMID- 4205845 TI - Fluorescent antibody studies in malignant melanoma. AB - Sera from 57 patients with malignant melanoma and 39 control patients were tested by immunofluorescence techniques against 6 melanoma cell lines. Thirty-two per cent of tests with sera from melanoma patients showed fluorescence with these cell lines whereas only 17% of tests with control sera were positive. Reactions occurred in 21% of tests with sera from patients with primary melanoma compared with 40% with secondary melanomata and 54% with "cured" melanomata. The cell lines varied in antigenicity but this did not correlate with either pigmentation or length of time in culture. The cell lines which were most reactive with sera from melanoma patients were also most reactive with control sera. PMID- 4205846 TI - Chronic prostatitis--an Australian view. PMID- 4205847 TI - Studies on carcinogenic azo dyes. 3. Retention of tritium during enzymatic hydroxylation of 3'-methyl-4-dimethylaminoazobenzene(4'-3H or 5'-3H) or chemical substitutions of the related compound, and the effect of the repeated administration of this azo dye on the retention of tritium. PMID- 4205848 TI - [Auto-regulatory pacemaker in emergency treatment of Adams-Stokes syndrome caused by antimony poisoning]. PMID- 4205849 TI - [Treatment of cardiac arrhythmia with direct current electric countershock]. PMID- 4205850 TI - [Ischemic disorders of the vertebro-basilar artery system]. PMID- 4205851 TI - [Excision and prosthetic replacement of cervical spine tumors (report of 5 cases)]. PMID- 4205852 TI - [Small vessel anastomosis. V. Effect of anticoagulant therapy on patency rate]. PMID- 4205854 TI - [The development of primary lung carcinoma and x-ray findings]. PMID- 4205853 TI - [Summary of 15-year experience in neonatal care--clinicopathologic study of 1,074 cases]. PMID- 4205855 TI - [Experimental studies on prevention of muscular cramps caused by 2 F-type schistosomicides]. PMID- 4205856 TI - [Orbital tumors]. PMID- 4205857 TI - [Complications of pacemakers in heart block and their prevention]. PMID- 4205858 TI - [Clinicopathological discussion No. 11. Headache with paroxysmal palpitation and excessive perspiration of 2 years' duration, later associated with high fever and shock]. PMID- 4205859 TI - [Manufacture and clinical application of cardiac pacemakers]. PMID- 4205860 TI - [Reimplantation of severed limbs: analysis of 40 cases]. PMID- 4205861 TI - [Reimplantation of severed limbs. Some knowledge gained from practice]. PMID- 4205862 TI - [Experience in reimplantation of severed fingers]. PMID- 4205864 TI - [Transplantation of severed left foot onto right leg. Report of a case]. PMID- 4205865 TI - [Autotransplantation of severed foot. Report of a case]. PMID- 4205863 TI - [Functional recovery in reimplantation of the extremities]. PMID- 4205866 TI - [Experiments in transplantation of severed limbs]. PMID- 4205867 TI - [Regeneration of veins and lymphatics after limb reimplantation in dogs]. PMID- 4205868 TI - [Low molecular weight dextran im epidemic hemorrhagic fever]. PMID- 4205869 TI - [Cerebellar hemorrhage]. PMID- 4205870 TI - [Uremic hemorrhagic pericarditis in chronic hemodialysis patients (apropos of 5 cases)]. PMID- 4205871 TI - Ocular hypertensive response to alkali burns in the monkey. PMID- 4205872 TI - [Early reactions of lymphatic tissue in cases of experimental infections of mice with strains of acid-fast bacilli of varying virulence]. PMID- 4205873 TI - The use of blood. PMID- 4205874 TI - An apparatus for the measurement of lipoxygenase activity and pentane production. PMID- 4205875 TI - Studies on the antitumor activity of an alazopeptin isolated from a new strain of Streptomyces. PMID- 4205876 TI - Letter: The probable identity of bacilysin and tetaine. PMID- 4205877 TI - Letter: Fusaric acid derivatives: the effect on dopamine beta-hydroxylase. PMID- 4205878 TI - The effect of sea star coelomocyte extract on cell-mediated resistance to Listeria monocytogenes in mice. AB - Mice treated with sea star factor (SSF), a protein extracted from sea star coelomocytes, became highly susceptible to infection with a normally sublethal dose of Listeria monocytogenes. This was in contrast to the expected result of increased resistance originally postulated because of the macrophage-activating properties of SSF. Enhanced susceptibility was seen when SSF was given from 96 h before to 48 h after infection with Listeria. Mice pretreated with SSF failed to develop immunity to Listeria when given a dose of organisms capable of immunizing nontreated mice. Treatment of immune mice with SSF did not alter their immune status. In addition, incubation of immune lymphocytes with SSF in vitro did not alter their ability to adoptively transfer immunity to normal recipients. Immune lymphocytes treated with SSF and then incubated with anti-SSF and C did, however, lose the ability to transfer immunity. These results suggest that SSF enhances infection by binding to T lymphocytes, inhibiting their replication upon contact with Listeria antigen and thus preventing the generation of a population of sensitized lymphocytes capable of effecting anti-Listeria immunity. PMID- 4205879 TI - Synergism between ecologic and immunologic control mechanisms of intestinal flora. PMID- 4205880 TI - Resistance of Neisseria gonorrhoeae to phagocytosis: relationship to colonial morphology and surface pili. PMID- 4205881 TI - Pyelonephritis. XVII. Comparison of combinations of vancomycin, ampicillin, streptomycin, and gentamicin in the treatment of enterococcal infection in rats. PMID- 4205882 TI - New drugs--no. 14. Glibenclamide. Mechanism of action. PMID- 4205884 TI - The value of radiotherapy in the management of malignant melanoma of the nasal cavity. PMID- 4205883 TI - Auto-immunity in nasal allergy. PMID- 4205885 TI - Gonococcal ophthalmia neonatorum. Relationship of time of infection to relevant control measures. PMID- 4205886 TI - Total parenteral nutrition and Crohn's disease. PMID- 4205887 TI - Mechanisms of carbohydrate-induced hypertriglyceridemia. PMID- 4205888 TI - Tuberculosis in Acukland. PMID- 4205889 TI - Intensive monitoring for adverse drug effects in patients discharged from acute medical wards. PMID- 4205890 TI - [Perforation of jejunal diverticulum by a non-metallic foreign body]. PMID- 4205891 TI - Study of the mutation process induced by N-nitrosomethylurea at various stages of spermatogenesis of Drosophila melanogaster. Fertility, crossing-over, and recessive sex-linked lethal mutations. PMID- 4205892 TI - Cytological investigation of crossovers induced by irradiation in males of Drosophila melanogaster. PMID- 4205893 TI - Investigation of the mutagenic activity of phenothiazines and other drug preparations. PMID- 4205894 TI - New boron-induced puffs and modificational localization of a gene. PMID- 4205895 TI - Study of the competitive capacity of Drosophila melanogaster individuals heterozygous for radioinduced mutations. PMID- 4205896 TI - [Increase of the sensitivity of pathogenic microbes to antibiotics with the aid of ribonuclease]. PMID- 4205897 TI - [Characteristics of the microflora in the inflammatory urinary tract diseases]. PMID- 4205898 TI - Hemochromatosis presenting as diabetic ketoacidosis with extreme hyperglycemia. PMID- 4205899 TI - Studies on tetrapeptides related to thyrotropin releasing hormone and luteinizing hormone releasing hormone. PMID- 4205900 TI - The effect of anti-inflammatory drugs on the aggregation and adhesiveness of platelets, red cells and leukocytes. PMID- 4205901 TI - Status and prospects of research in hereditary deafness. PMID- 4205902 TI - Longitudinal differentiation of chromosomes. PMID- 4205903 TI - Localization of gene function. PMID- 4205904 TI - Dosage compensation in Drosophila. PMID- 4205905 TI - Recombination deficient mutants of E. coli and other bacteria. PMID- 4205906 TI - [Studies on the present state of resistance to framycetin among strains of staphylococci, enterobacteriaceae and pseudomonas]. PMID- 4205907 TI - Levodopa in the treatment of arterial insufficiency of the lower limbs. Clinical and rheographic trial. PMID- 4205908 TI - Unprimed glucan biosynthesis by a particulate ADP-glucose-glucan glucosyl transferase from an Escherichia coli mutant and its stimulation by a protein factor. PMID- 4205909 TI - Methylation of 4-thio-2'-deoxyuridylate by thymidylate synthetase. PMID- 4205910 TI - Rat serum albumin biosynthesis: evidence for a precursor. PMID- 4205911 TI - [Localization and extension taken by activity sites of the enzymes delta 5 3beta HSDH and delta5 17beta HSDH in the ovary of the adult female hybrid (Pekin male X Barbary female) before its transformation]. PMID- 4205912 TI - [Morphological study of the liver mitochondria of rats subjected to thyroidectomy and carbon tetrachloride poisoning]. PMID- 4205913 TI - [Plasma LH levels in the prepuberty heifer subjected to superovulation treatment]. PMID- 4205914 TI - [Gangliosides of a clone of neuroblastoma cells]. PMID- 4205915 TI - [Effects of a 28-hour day-night cycle on fertilization and embryo mortality rates in the domestic chicken (Gallus gallus)]. PMID- 4205916 TI - [Particular interest of culture for the demonstration of free amoebas likely to invade human beings and become pathogenic]. PMID- 4205917 TI - [Ultrastructural study of the ovocyte in the amphipode crustacean Orchestia gammerella Pallas]. PMID- 4205918 TI - [Appearance of the "female protein fraction" in the hemolymph and the modalities of the appearance of puberty in the female Orchestia gammarella Pallas (Crustacea, Amphipoda)]. PMID- 4205919 TI - [Consequences of experimental augmentation of the number of medullary cells on early organogenesis of the embryonal gonad of the common toad, Bufo bufo L]. PMID- 4205920 TI - [Morphogenic interactions between reptilian epidermis and birds or mammalian dermis]. PMID- 4205921 TI - [Ecto-mesodermic interaction in the establishment of dorso-ventral polarity in the chick embryo foot]. PMID- 4205922 TI - [In vitro induction of crystalline lens in presumptive trunk ectoblasts or in the opaque area in chick embryo blastoderm]. PMID- 4205923 TI - [Isolation of messenger RNAs from thyroglobulin and their translation in the oocyte of Xenopus]. PMID- 4205924 TI - [Effect of cysteamine on Escherichia coli treated with methylglyoxal: effect on protein synthesis]. PMID- 4205925 TI - [Persistance of cytotoxic activity against a syngeneic tumor after removal of the tumor]. PMID- 4205926 TI - [Morphological changes in cultures of hamster embryo cells after treatment with chemical carcinogens]. PMID- 4205927 TI - Clearance rate of exogenous 3H-thymidine from the plasma of pregnant rhesus monkeys. PMID- 4205928 TI - Beta trace protein. Purification and urinary excretion studies in selected diseases. PMID- 4205929 TI - Quantitative determination of IgE by single radial immunodiffusion. A comparison of three different methods for intensification of precipitates. PMID- 4205930 TI - Significance of C-reactive protein binding by lecithin: a simplified procedure for CRP isolation. PMID- 4205931 TI - Analytical characterization of the urinary proteins from sixty patients with monoclonal gammopathies. PMID- 4205932 TI - A major role of the fifth component of complement (C5) in the opsonization of yeast particles. Partial dichotomy of function and immunochemical measurement. PMID- 4205933 TI - Nutrition and cell growth. PMID- 4205934 TI - Case report. Diverticulum of pharyngoesophageal junction. PMID- 4205935 TI - Murein hydrolases in the envelope of Escherichia coli. Properties in situ and solubilization from the envelope. PMID- 4205936 TI - Studies on the catalytic mechanism of a serine protease from Streptomyces griseus. PMID- 4205938 TI - Succession & stratification of organisms in sewage oxidation pond. PMID- 4205937 TI - Competition in Drosophila. 3. A possible maternal effect. PMID- 4205939 TI - Cytological effect of versene on the production of dicentric bridges in spermatocytic chromosomes of grasshopper, Spathosternum prasiniferum Walker. PMID- 4205940 TI - Characterisation & identification of two aerobic spore forming bacteria producing extracellular glutamic acid & valine respectively. PMID- 4205941 TI - Staphylococcal enterotoxin synthesis during the exponential, transitional, and stationary growth phases. AB - Small inocula (1 to 10 colony-forming units per ml of broth) of Staphylococcus aureus strains S-6, S-6R, and FRI-100 were employed to study growth and enterotoxin synthesis in 4% protein hydrolysate powder broths. For each strain, the exponential growth phase ended once the population approached 10(9) to 2 x 10(9) colony-forming units per ml. By that time, the concentrations of enterotoxins A and B reached the minimal level (1 to 2 mug/ml) at which the single gel diffusion tube method becomes applicable. By microslides and reverse passive hemagglutination, enterotoxins A and B were found to be synthesized during the exponential growth phase, but at different exponential rates. PMID- 4205942 TI - Peptic digestion of streptococcal M protein. I. Effect of digestion at suboptimal pH upon the biological and immunochemical properties of purified M protein extracts. AB - Purified streptococcal M protein vaccines often produce non-type-specific immunotoxic reactions in the skin or the blood of humans. In an attempt to free the type-specific M antigen (TSM) of such non-type-specific (NTSM) immunotoxic properties, purified M protein preparations were subjected to brief periods (5 to 10 min) of enzymatic digestion in dilute solutions of pepsin (20 mug/ml) at pH 5.0. Such peptic digestion abolished the ability of M protein to aggregate platelets in human platelet-rich plasma and to precipitate plasma fibrinogen. It greatly reduced (up to 16-fold) the capacity of M protein to react with the NTSM complement-fixing antibody that is normally present in human serum. In contrast, it had no effect upon the reactivity of the type-specific M antigen; the pepsin treated M protein retained its ability to inhibit type-specific streptococcal opsonization by homologous M antibody, and, moreover, retained its ability to elicit type-specific opsonic antibody responses in rabbits. PMID- 4205943 TI - Eperythrozoon coccoides. II. Effect on interferon production and role of humoral antibody in host resistance. AB - Eperythrozoon coccoides was shown to inhibit the interferon response in mice only during the first 3 weeks after acute infection. By 6 weeks the production of interferon in response to Newcastle disease virus returned to a normal level. Antibody to E. coccoides could be demonstrated by three methods: (i) neutralization, (ii) indirect fluorescent antibody, and (iii) gel diffusion. The clearance of the parasitemia could be correlated with the appearance of circulating antibody. The critical role of humoral antibody was confirmed by evidence that immunosuppressive therapy prevented, in an infected animal, clearing of E. coccoides from the blood and converted a nonlethal infection to one with a 100% mortality. Administration of immune serum to the E. coccoides infected, immunosuppressed animal, however, resulted in clearing of the parasitemia and prevention of death. Finally, a series of immunosuppressive regimens failed to exacerbate E. coccoides in animals after recovery from the acute phase of infection. E. coccoides may not be as important a laboratory contaminant as postulated originally. PMID- 4205944 TI - Antibody-mediated inhibition of dextran-sucrose-induced agglutination of Streptococcus mutans. AB - Immune sera to strains of Streptococcus mutans were found to inhibit agglutination of bacterial suspensions to which either high-molecular-weight dextran or sucrose was added. This inhibitory activity was shown to be mediated by antibody of the immunoglobulin G class. A semiquantitative assay was developed which demonstrated cross-inhibition of dextran/sucrose-induced agglutination among several strains of S. mutans. Antiserum to a partially purified glucosyltransferase was found to lack agglutination inhibition activity, consistent with the hypothesis that the dextran-binding antigen detected by the assay is immunologically distinct from the glucan-synthetic enzyme. A model for glucan synthesis and binding consistent with the reported data is described. PMID- 4205945 TI - Development of a purified cholera toxoid. I. Purification of toxin. AB - The enterotoxin from Vibrio cholerae is selectively concentrated from cell-free culture supernatant by co-precipitation with hexametaphosphate and is further purified by adsorption on aluminum hydroxide powder. The bulk of residual somatic antigen becomes insoluble upon lyophilization of the toxin preparation and is removed by centrifugation of the rehydrated material. Other contaminants are eliminated by treatment with activated carbon. Preparations of toxin, purified by this method, have been characterized by: (i) a single immunoprecipitin line against polyvalent antisera; (ii) homogeneity on acrylamide gels; (iii) specific activities on the order of 22 limit-of-bluing doses/mug; (iv) ultraviolet spectra characteristic of pure protein; and (v) overall yields on the order of 50%, irrespective of purification scale. Such preparations, however, have been shown to contain trace amounts of somatic antigen when they are intensively tested either for their ability to elevate serum vibriocidal antibody titers in immunized rabbits or for their ability to increase resistance of immunized mice to live vibrio challenge. In the latter test system, the level of residual somatic antigen per 50 mug of toxin (toxoid) antigen generally did not exceed 0.025% of the Division of Biological Standards reference vaccine, V. cholerae Inaba IN-12. Methods for elimination of this small amount of somatic antigen have been investigated and are discussed. The particular combination of purification steps which are presently described have been easily and reproducibly applied on a production scale to prepare gram amounts of toxin with a high degree of purity, even under a variety of initial conditions. PMID- 4205946 TI - Development of a purified cholera toxoid. II. Preparation of a stable, antigenic toxoid by reaction of purified toxin with glutaraldehyde. AB - Evidence is presented which confirms that cholera toxoids obtained by reaction of purified toxin with Formalin possess the ability to partially reactivate both in vivo and in vitro. At the same time, conditions are presented for the preparation of stable, antigenic cholera toxoids by reaction of purified toxin with glutaraldehyde. Treatment of purified cholera toxin with approximately 200 mol of glutaraldehyde per mol of toxin at pH 7.8 reproducibly resulted in the preparation of toxoids which: (i) possessed less than 20 bluing doses per 100 mug; (ii) did not reactivate in vivo or in vitro; (iii) precipitated with, and neutralized antitoxin; (iv) elevated prolonged serum antitoxin in immunized rabbits; (v) protected immunized guinea pigs against toxin skin challenge; and (vi) lent themselves to enhanced antigenicity by means of an in situ adjuvant system which may be suitable for man. Acrylamide gel electrophoresis and molecular sieve chromatography of a series of glutaraldehyde-derived toxoids suggested that the reaction products consisted of monomeric and polymeric species and that the proportion of higher-molecular-weight species was determined by the relative concentrations of toxin and glutaraldehyde. The results suggested a relationship between complete and irreversible elimination of toxicity and the formation of higher-molecular-weight toxoids. PMID- 4205947 TI - Vi antigen from Salmonella typhosa and immunity against typhoid fever. I. Isolation and immunologic properties in animals. AB - The role of Vi antigen in human immunity against typhoid fever has been debated for decades. Circumstantial evidence indicates that Vi antigen may play a role in pathogenicity and immunity. A Vi preparation was isolated from Salmonella typhosa, the causative organism in human typhoid fever, by a mild precipitation method. It was significantly more potent in animal studies than preparations from Citrobacter used in the past for human study and less toxic than conventional typhoid vaccines. With this antigen, the role of Vi antigen in human protection is now being investigated. PMID- 4205948 TI - Relationship of antimicrobial cellular immunity to delayed hypersensitivity in Listeriosis. AB - The relationship of antimicrobial cellular immunity to delayed hypersensitivity (DH) was studied in mice antigenically stimulated by living Listeria monocytogenes confined to diffusion chambers in peritoneal cavities or by subcutaneous inoculation of sublethal doses of the organism. Mice showed DH reactions when tested 6 days after inoculation, and reactions were positive for at least 90 days in some mice. DH also became established when the mice were stimulated by antigens diffusing from peritoneal chambers containing viable Listeria. Mice were categorized as DH positive or DH negative if they developed more or less than a 5% increase in foot volume 24 h after the injection of Listeria antigen. Some antigenically stimulated mice did not elicit the DH reaction. Consequently, the animals were arranged as immunized groups (DH positive and DH negative) and Listeria chamber implant groups (DH positive and DH negative). When challenged with L. monocytogenes, all four groups were significantly resistant as compared with controls. Thus, the in vivo tests for immunity and DH did not show direct correlation. The results suggested that antimicrobial cellular immunity can occur as a phenomenon independent of DH. Evidence for antimicrobial cellular immunity as the principle mechanism of resistance in murine listeriosis is discussed with consideration for possible heterogeneity of function by thymus-derived lymphocytes. PMID- 4205949 TI - Feline immunoglobulins. AB - Immunoglobulins (Ig) in feline sera and secretions were identified by immuno electrophoresis and immunodiffusion with rabbit antisera prepared to feline IgG, IgA, IgM, and whole serum. Adult cat sera, colostral whey, postcolostral sera, tears, and nasal secretions contained IgG, IgA, and IgM. IgG was the only Ig identified in precolostral sera and cerebrospinal fluid. Milk, intestinal contents, pooled allantoic and amniotic fluids, and saliva from adult cats and urine from suckling kittens contained IgG and IgA. Ig were not detected in urine from adult cats. Bile was unique in that IgA and IgM were the predominant Ig. PMID- 4205950 TI - Mechanism of adherence of Streptococcus mutans to smooth surfaces. II. Nature of the binding site and the adsorption of dextran-levan synthetase enzymes on the cell-wall surface of the streptococcus. AB - The mechanism of adsorption of the Streptococcus mutans enzymes responsible for the synthesis of insoluble dextran-levan to the S. mutans cell-wall binding sites has been studied. Certain characteristics of these binding sites are presented. The adsorption of these enzymes to the cell surface occurred rapidly without the addition of a source of energy and over a pH range of 3 to 11. The adsorption was inhibited by soluble dextran, probably due to the strong affinity of the polymer to the enzyme. All other polymers and sugars studied showed little or no inhibition. The adsorption was also inhibited by antibody globulin to the a-d immunologically specific group antigen surface polysaccharide of S. mutans and by anti-dextran globulin. The inhibition by anti-a-d globulin is considered to be due to a restriction of access of enzyme to the binding site of the enzyme which may be located in close proximity to the group antigen. On the other hand, anti dextran globulin appeared to directly inhibit the adsorption by covering the binding site. Dextranase destroyed the binding site and released glucose from the S. mutans cells. These data indicate that S. mutans grown in media containing glucose possesses a small amount of dextran on the cell surface, and that this dextran is, or is a part of, the binding site for enzymes which synthesize the insoluble dextran-levan polymer. Trypsin inhibited the synthesis of insoluble polysaccharide and the adherence of cells. It is not clear in this case that destruction of the binding sites occurred. These data present a partial explanation of the processes which may be concerned in the formation of dental plaque on the smooth surfaces of teeth. PMID- 4205951 TI - Biological and physical properties of the suckling mouse cataract agent grown in chicken embryos. AB - Experiments were carried out with the suckling mouse cataract agent (SMCA) in an attempt to better characterize the nature of this agent. Despite the fact that high titers of SMCA were found in the chorioallantoic fluid of inoculated chicken embryos, the agent did not replicate in chicken embryo epithelial cell cultures. SMCA did not interfere with Sindbis virus plaque formation and was not inhibited by chicken interferon or polyinosinic-polycytidylic acid. The agent was relatively resistant to high pH and osmotic shock but was inactivated by low pH. Electron micrographs of negatively stained particles concentrated and semipurified from infected chicken embryo chorioallantoic fluids revealed pleomorphic particles ranging from approximately 70 to 400 nm in diameter. SMCA was resistant to kanamycin, novobiocin, and sodium aurothiomalate. PMID- 4205953 TI - Decreased susceptibility to Listeria monocytogenes in mice after infection with Trichinella spiralis. AB - Mice challenged intravenously with Listeria monocytogenes at 7 or 21 days after Trichinella spiralis infection demonstrated a higher mean lethal dose and longer survival time than normal mice. This effect of helminthic infection was abrogated after 49 days. PMID- 4205952 TI - Nonspecific inhibition of growth of intracellular Listeria monocytogenes by lymphocyte culture products. AB - Supernatant fluids from mycobacteria-immune and mitogen-stimulated lymphocyte cultures were able to inhibit the intracellular growth of listeria in listeria infected macrophages. PMID- 4205954 TI - Maturation-inducing substance in starfishes. PMID- 4205955 TI - Report on drugs, acidic and neutral nitrogenous organics. PMID- 4205956 TI - Report on multiresidue methods (interlaboratory studies). PMID- 4205957 TI - Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). II. Catecholamine-containing groups. PMID- 4205958 TI - Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). 3. Serotonin-containing groups. PMID- 4205959 TI - The morphology of retinal neurons of the owl monkey Aotes. PMID- 4205960 TI - A clinical trial of a calculus-inhibitory dentifrice. PMID- 4205961 TI - [Studies on carcinogenic azo dyes. IV. Differences in the metabolism of 3'-methyl 4-dimethylaminoazobenzene(5'-3H) by the liver homogenate of rat, mouse, or hamster (author's transl)]. PMID- 4205962 TI - [Possibility of inducing mutations in Drosophila melanogaster through the action of chlorophos]. PMID- 4205963 TI - [Oxidation of naphthalene and salicylic acid by bacteria of the genus Pseudomonas]. PMID- 4205964 TI - [Decomposition of peat humic acid by associative microorganism cultures]. PMID- 4205965 TI - [Formation of the infectious form of the blue-green algae virus in plant tissue culture]. PMID- 4205966 TI - [Immunochemical study of the antigens isolated from Leptospira]. PMID- 4205967 TI - [Antiviral properties of bacteria and their metabolites]. PMID- 4205968 TI - Total replacement of the elbow joint. PMID- 4205969 TI - Porcine congenital infection due to Mycobacterium tuberculosis typus avium. PMID- 4205970 TI - Effects of epinephrine and progesterone on the ocular hypertensive response to intravenous infusion of prostaglandin A2. PMID- 4205971 TI - Pregnancy blockade by indomethacin, an inhibitor of prostaglandin synthesis: its reversal by prostaglandins and progesterone in mice. PMID- 4205972 TI - Effect of metal-complexing agents on the oxygenase activity of sheep vesicular glands. PMID- 4205973 TI - Arachidonic acid-induced human platelet aggregation and prostaglandin formation. PMID- 4205974 TI - The embryo as a transplant. PMID- 4205976 TI - The selection of teaching-learning materials in health sciences education: report of a WHO study group. PMID- 4205975 TI - [Inactivation of the antibiotics in milk]. PMID- 4205977 TI - Toxicological evaluation of certain food additives with a review of general principles and of specifications. Seventeenth report of the joint FAO-WHO Expert Committee on Food Additives. PMID- 4205978 TI - Drug hydroxylation and glucuronidation in liver microsomes of phenobarbital treated rats. PMID- 4205980 TI - Repression of alkaline phosphatase synthesis by adenine, adenosine and adenine nucleotides in an adenine auxotroph of Bacillus anthracis. PMID- 4205979 TI - Investigation of the protease forming ability of Serratia marcescens and one of its mutant strains. PMID- 4205981 TI - Mycobacterium tuberculosis strains showing positive iron uptake. PMID- 4205982 TI - A cryptic prophage carried by Bacillus cereus. PMID- 4205983 TI - Whole body counting of 32P-endotoxin elimination in endotoxin-tolerant and control mice. PMID- 4205984 TI - Serological relationship between Pseudomonas aeruginosa and Enterobacteriaceae. II. Relationship of Pseudomonas aeruginosa O antigens to Escherichia, Shigella, Proteus, Morganella, Rettgerella and Providencia. PMID- 4205985 TI - Life span and fine structural changes in oxygen-poisoned Drosophila melanogaster. PMID- 4205986 TI - Simple, sensitive spectrophotofluorometric method for hydrazine in plasma. PMID- 4205987 TI - Application of the carbon cup atomisation technique in water analysis by atomic absorption spectroscopy. PMID- 4205988 TI - Synthesis of valinomycin by the phosphite method. PMID- 4205989 TI - [New findings on touch. A comparative appraisal of neurophysiological and morphological findings over the last few years]. PMID- 4205990 TI - [Modification of the osmotic resistance and the electrophoretic mobility of erythrocytes during hemolytic diseases with antibodies (auto and iso-antibodies). Comparison with sensitized erythrocytes in vitro]. PMID- 4205991 TI - [Presence of free lysopine in tissue cultures of various origins]. PMID- 4205992 TI - [Mitotic ultrastructures in a pyloric endocrine cell of the newborn rabbit]. PMID- 4205993 TI - [Morphogenic necrosis and phagocytosis studied in the chicken embryo foot by scanning electron microscopy]. PMID- 4205994 TI - [Excretion of an acute sodium load by a line of spontaneously hypertensive rats]. PMID- 4205995 TI - [Effect of various nutritive intravenous perfusions on the oral intake in the rat]. PMID- 4205996 TI - [Demonstration of autostimulation behavior in the substantia grisea centralis of the rat]. PMID- 4205997 TI - [Depletion of adrenal adrenaline in newborn rats and rabbits]. PMID- 4205998 TI - [Presence of a mitogenic factor in the soluble extracts of colonic tumors]. PMID- 4206000 TI - [Preparation of antitoxic and antimicrobial vaccines using glutaraldehyde]. PMID- 4205999 TI - [Interaction of a fluorescent ligand with the protein receptor of acetylcholine present in Torpedo marmorata membrane fragments]. PMID- 4206001 TI - [Influence of temperature on the structural 8S light RNA present in murine sarcoma virus (Moloney strain)]. PMID- 4206002 TI - [Ultrastructural study of the morphogenesis of the thyroid follicle: reorganisation of pig thyroid cells in culture]. PMID- 4206003 TI - [Demonstration by activated trace autoradiography of nucleolar DNA synthesis in the liver of the adult rat]. PMID- 4206004 TI - [Use of a microtechnic for the determination of the enzyme activity of spermatozoa and semen in the rabbit and the bull]. PMID- 4206005 TI - [Effects of reserpine on heart rate and thermoregulation in the active and normothermic hedge hog (Erinaceus europaeus L.) and in the hibernating hedge hog]. PMID- 4206006 TI - [Bungarus fasciatus venom and neuromuscular transmission. Study by the method of calcium cholinergic response on the mouse diaphragm]. PMID- 4206007 TI - [Detour behavior in the constructive activity of the Saintonge termite (Reticulithermes lucifugus santonensis)]. PMID- 4206008 TI - [Action of juvenile hormone mimetic substances on the heart rate of Locusta migratoria L. and Schistocerca gregaria Forsk]. PMID- 4206009 TI - [Moulting hormone and DNA synthesis in cockroach embryo epidermal in vitro cultured cells]. PMID- 4206010 TI - [Study of the progression of a chicken Wolffian canal in the mesonephrotic territory of the quail]. PMID- 4206011 TI - [Effect of soluble molybdenum level in the sail on the microflora of the nitrogen cycle. Agronomic applications]. PMID- 4206013 TI - [Characterization of the acid proteins of hepatocyte chromatin of the pig]. PMID- 4206012 TI - [Inhibitory effect of caffeine on the induction of cutaneous cancers by ultraviolet rays in the mouse]. PMID- 4206014 TI - [Free organic radical and maximal longevity in mammals and birds]. PMID- 4206016 TI - [Phagocytosis of group A streptococcus (Streptococcus pyogenes) by normal and immune macrophages of the mouse]. PMID- 4206015 TI - [Effect of calcium on the desensitization of isolated guinea pig ileum to scorpion venom]. PMID- 4206017 TI - Editorial: home dialysis or transplantation. PMID- 4206018 TI - The familial nephrotic syndrome. II. A clinicopathological study. PMID- 4206019 TI - Growth in children with renal disease with particular reference to the effects of calorie malnutrition: a review. PMID- 4206020 TI - Effects of calcium and strontium on divalent ion content of refractive granules in Tetrahymena pyriformis. PMID- 4206021 TI - Role of specific sperm antigens in fertilization. PMID- 4206022 TI - Observations on alternative health strategies. PMID- 4206023 TI - Blood bank inventory policies: a computer simulation. PMID- 4206024 TI - Analysis of multiple sources of variation: comparison of three techniques. PMID- 4206025 TI - Isolation of an acidic surface antigen from a conventional strain of Staphylococcus aureus. AB - Staphylococcus aureus strain 7007, a prototype isolated from a hospital burn unit, was shown to exhibit a significant degree of resistance to ingestion by mouse polymorphonuclear leukocytes. An acidic surface antigen was isolated from strain 7007 by a combination of 10% trichloroacetic acid extraction, ion-exchange chromatography, and gel filtration. Chemical analysis indicated that the surface antigen consists of an unknown aminouronic acid and an amino sugar. Immunochemical analysis suggested that the 7007 antigen is a common feature of all the strains collected from the burn unit. No cross-reactivity was observed between the carbohydrate preparations of various hospital staphylococcal strains and the 7007 heteropolymer. These results suggested the possibility that the surface antigen of strain 7007 represents a strain- or type-specific antigen. PMID- 4206026 TI - Effects of carbon dust inhalation on the cell-mediated immune response in mice. AB - The effects of carbon dust inhalation on the bone marrow-derived (B) and thymus derived (T) lymphocyte populations of spleen and mediastinal lymph node (MLN) cultures were examined. The concanavalin A (Con A)-responsive cell population (T cells) in the spleen was found to be depressed after 7 days of pre-exposure to carbon dust. However, this effect was transient, and after 14, 21, and 28 days of pre-exposure to carbon dust, the Con A-responsive cells exhibited a 30 to 40% enhancement over control group responses. Conversely, Con A-responsive cells in the pooled MLN cultures exhibited depression, ranging from 22 to 33% below control group values, after 7, 14, and 28 days of pre-exposure to carbon dust. The lipopolysaccharide (LPS)-responsive cell population (B cells) in the spleens of carbon-exposed mice was found not to differ significantly from control group values after all times of pre-exposure. LPS-responsive cells in the MLN cultures exhibited enhancement, ranging from 49 to 74% above control values, after 14, 21, and 28 days of pre-exposure to carbon dust. The ability of carbon spleen cell cultures from carbon-exposed mice to undergo antigen induced blast transformation after sensitization with Mycobacterium tuberculosis H37Ra was also determined. Mice exposed to carbon dust inhalation 2 weeks before and 3 weeks after aerosol or subcutaneous immunization exhibited significantly enhanced ratios of transformation upon culture of their spleen lymphocytes with purified protein derivative of tuberculin. PMID- 4206027 TI - Pseudomonas aeruginosa exotoxin in mice: localization and effect on protein synthesis. AB - We studied the fate of (125)I-labeled Pseudomonas aeruginosa (PA 103) exotoxin injected intravenously into mice and the effect of the exotoxin on the protein synthesis of various organs. After 2 h, only 5% of the injected label remained in the blood, in comparison with 30% of the injected control, consisting of [(125)I]bovine serum albumin. The highest concentration of radioactivity was consistently observed in the kidneys of toxin-treated mice. Lesser amounts of the label were found in the liver and the spleen. The heart, pancreas, lung, and brain showed very little uptake. Approximately 30% of the label (non trichloroacetic acid precipitable) was recovered from the urine within 2 h after the injection. The behavior of [(125)I]toxoid was similar to that of the [(125)I]toxin. In contrast, in [(125)I]bovine serum albumin-treated mice, the label was uniformly distributed among the organs examined, and the concentration was low. After intravenous administration of the exotoxin, a 50% inhibition of protein synthesis was observed in the liver within 4 h, and virtually complete inhibition was observed shortly before the time of death. Kidney and spleen displayed slight reduction of protein synthesis at 2 to 4 h and approximately 50% reduction during the terminal stage. It appeared that the highest concentration of the toxin occurred in the kidney, where it was degraded, but its greatest toxic effect took place in the liver. PMID- 4206029 TI - Immunological study of the heat-labile enterotoxins of Escherichia coli and Vibrio cholerae. AB - Immunodiffusion experiments were conducted to associate a precipitin line with Escherichia coli heat-labile enterotoxin (LT). Wild strains of porcine and of human enteropathogenic E. coli as well as laboratory-derived enterotoxigenic variants of E. coli K-12 were used for LT antigen preparations. These were produced mainly by ultrafiltration and ammonium sulfate precipitation of broth culture supernatants. When antisera with anti-LT activity were reacted with antigen preparations from Ent(+) and Ent(-) variants of E. coli K-12, a line "a" was given by Ent(+) but not by Ent(-) preparations. Line "a" was removed by absorption of anti-LT serum with antigen preparation from an Ent(+)E. coli K-12, but was unaffected when the antigen preparation used to absorb the serum was from an Ent(-)E. coli K-12. A line identical to "a" was given by antigen preparations from wild strains of porcine enteropathogenic E. coli reacted with homologous or heterologous anti-LT sera. One human strain of enteropathogenic E. coli was shown to possess an antigen identical to that which gave rise to line "a." To demonstrate this line it was necessary to use high concentrations of gammaglobulin and high concentrations of the crude antigen preparations. LT preparations reacted with anticholera toxin to give a line "c," which showed a reaction of partial identity with line "b" produced by reaction of pure choleragenoid and anticholera toxin. Lines "a" and "c" gave reactions of identity. PMID- 4206028 TI - Stability of the rabbit immunogenic marker of RA 27-3 rubella vaccine virus after human passage. AB - Rabbits were inoculated intravenously with "wild" rubella virus, RA 27/3 rubella vaccine virus, or rubella virus isolated from recipients of RA 27/3 vaccine. Rabbits receiving "wild" virus developed rubella hemagglutination inhibition antibody, and those receiving vaccine virus did not. One of the five reisolates tested produced a low transient antibody response in two of the five rabbits inoculated with this strain. The study indicates that the rabbit immunogenic marker after intravenous injection can be used to determine if a rubella virus isolated from a patient is of "wild" or vaccine origin. There was no significant change in the reduced immunogenicity characteristics of the RA 27/3 vaccine virus after human passage. PMID- 4206031 TI - Changes in the scintigraphic aspects of liver after partial high-energy irradiation. PMID- 4206030 TI - Mechanisms of immunity in typhus infections. IV. Failure of chicken embryo cells in culture to restrict growth of antibody-sensitized Rickettsia prowazeki. AB - Rickettsia prowazeki, pretreated with typhus immune human serum, readily infects, and grows in, chicken embryo cells in culture. This finding is similar to those of previous studies which showed that typhus rickettsiae, pretreated with immune serum, grow in cells of the yolk sac of embryonated hen eggs and in the cells of the midgut of the human body louse. In contrast, identically treated typhus rickettsiae were destroyed by human macrophages in culture. Collectively, these observations seem to support an emerging concept that the fate of antibody sensitized typhus rickettsiae depends upon the presence or absence of certain specialized properties of the host cell into which they gain entrance nonphagocytic cells or "nonprofessional" phagocytic cells versus certain kinds of "professional" phagocytes. The phenomena involved probably have an important bearing on the mechanisms of the persisting infection and the nonsterile immunity which characterizes convalescence from typhus fever in man. They also form the basis for certain practical technical innovations in the laboratory. PMID- 4206032 TI - The densities of colloidal iron hydroxide particles bound to microvilli and the spaces between them: studies on glutaraldehyde-fixed Ehrlich ascites tumour cells. PMID- 4206033 TI - An examination into the phenomenon of granulation, in mu particles of stock 540 Paramecium aurelia. PMID- 4206034 TI - [Diverticula of Vaters' ampulla (apropos of 6 cases)]. PMID- 4206035 TI - Review of the toxicity of hexachlorophene, including its neurotoxicity. PMID- 4206036 TI - Hexachlorophene and the food and drug administration. PMID- 4206037 TI - Hexachlorophene in perspective. PMID- 4206038 TI - Filamentous bacterial viruses. XI. Molecular architecture of the class II (Pf1, Xf) virion. PMID- 4206039 TI - [Severe postoperative thyrotoxic attack treated by artificial hibernation]. PMID- 4206040 TI - [Prenatal blood transfusions for anti-D-erythroblastosis in twin pregnancies (author's transl)]. PMID- 4206041 TI - [Inhibition of premature labour--anti-inflammatory agents in the prevention of premature birth (author's transl)]. PMID- 4206042 TI - [Results in the treatment of allergic asthma using disodium cromoglycate (Intal)]. PMID- 4206043 TI - [Blood coagulation changes through dipropyl-acetic-acid (Ergenyl)]. PMID- 4206044 TI - [Respiratory insufficiency. Clinical views and suggestions for therapy for the practicing physician]. PMID- 4206045 TI - [Lung cancer and pulmonary tuberculosis as a combined disease]. PMID- 4206046 TI - [Problems of the diagnosis and prevention of pulmonary tuberculosis]. PMID- 4206047 TI - [Signifance of diffusion capacity for the diagnosis of lung diseases]. PMID- 4206048 TI - [Radioisotopes in the modern diagnosis of lung function]. PMID- 4206049 TI - [Computers in modern pulmonology]. PMID- 4206050 TI - [Proteolysis and obstructive pulmonary emphysema]. PMID- 4206051 TI - Cationic leukocyte antigen in urine of patients with chronic myelocytic leukaemia. PMID- 4206052 TI - Treatment of infective endocarditis--1973. PMID- 4206053 TI - The significance of protein disulfide and sulfhydryl groups in prostaglandin action. PMID- 4206054 TI - Measurement of prostaglandin f-2 alpha metabolites by radioimmunoassay. PMID- 4206055 TI - An inhibitor of the action of prostaglandins in sheep and human semen. PMID- 4206056 TI - [Roentgenological picture of the stomach after surgical treatment of intussusception of diverticulosis]. PMID- 4206057 TI - [Short-term buffering of the rumen using Montmorillonite (bentonite) in cattle under field conditions]. PMID- 4206058 TI - [Serological methods for the determination of Erysipelothrix pathogens]. PMID- 4206059 TI - [Isolation of atypical Mycobacteria and their local occurrence in the district of Komarno from 1965 to 1970]. PMID- 4206060 TI - [Diplostomosis and tylodelphosis of fishes in South Moravian nature parks]. PMID- 4206061 TI - Growth of Theileria parva-infected bovine lymphoid cells in whole-body irradiated mice. PMID- 4206062 TI - [Frequency of detecting Australia antigen at different phases of the disease of viral hepatitis in children]. PMID- 4206064 TI - [Isoimmunization to fetal erythrocytic (D) and leukocytic antigens]. PMID- 4206063 TI - [Phenobarbital in the pharmacotherapy of neonatal jaundices (a review of the literature)]. PMID- 4206065 TI - [Developmental and functional harms to the CNS due to malnutrition before and within short time after labor]. PMID- 4206066 TI - Proceedings: Radiation treatment of carcinoma of the nasal vestibule. PMID- 4206067 TI - Proceedings: Electron beam therapy of head and neck tumors. PMID- 4206068 TI - Proceedings: Time dose factors in radiation induced osteitis. PMID- 4206069 TI - Proceedings: Experimental verification of a method for varying the effective angle of wedge filters. PMID- 4206071 TI - Primary meningococcal pneumonia. PMID- 4206070 TI - Serologic studies in farmer's lung. Precipitins to the thermophilic actinomycetes. PMID- 4206072 TI - Possibilities and limitations of delegated literature searches by computer. PMID- 4206073 TI - A variation of the sulfide contraction procedure for synthesis of corrinoid systems. PMID- 4206074 TI - Formation of a 1-hydroxycorrin complex by photochemical A-D-secocorrin leads to corrin cycloisomerization. PMID- 4206075 TI - Photographing specimens immersed in fluid. PMID- 4206076 TI - Brain permeability of water. PMID- 4206077 TI - A monoclonal IgM with antibodylike specificity for phospholipids in a patient with lymphoma. PMID- 4206078 TI - Plasma cell dyscrasia associated with the production of incomplete (?deleted) IgGlambda molecules, gamma heavy chains, and free lambda chains containing carbohydrate: description of the first case. PMID- 4206080 TI - Insulin and growth hormone secretion in rats with ventromedial hypothalamic lesions maintained on restricted food intake. PMID- 4206079 TI - Cerebrovascular Moyamoya disease. PMID- 4206081 TI - Insulin degradation. IX. On the presence of glutathione-insulin transhydrogenase in human leukocytes. PMID- 4206082 TI - Sodium retention accompanying insulin treatment of diabetes mellitus. PMID- 4206083 TI - Kinetic studies of levansucrase of Bacillus subtilis. PMID- 4206084 TI - Phasing effects of light on cell division in exponentially increasing cultures of Tetrahymena grown at low temperatures. PMID- 4206085 TI - Interactions of retinol-binding protein with various chromophores and with thyroxine-binding protein. A model for visual pigments. PMID- 4206086 TI - Monographs on fragrance raw materials. PMID- 4206087 TI - Toxicology: cost-time. PMID- 4206088 TI - The relative susceptibility of four cephalosporins to a beta-lactamase from Bacillus cereus. AB - The effects of purified beta-lactamase from Bacillus cereus on the activity of four cephalosporins are described. Drug inactivation was measured spectrophotometrically and confirmed by microbiological assay and by microbiological techniques involving determinations of minimum inhibitory concentrations and growth curves of Staphylococcus aureus NCTC 6571 (Oxford) in broth containing drug +/- enzyme. Cephaloridine was the most sensitive of the four cephalosporins, followed by cephalothin and the sodium salt of 7 cyanacetamidocephalosporanic acid, with cephalexin considerably resistant to inactivation. The possible use of this beta-lactamase in the sterility testing of cephaloridine and cephalothin is examined. PMID- 4206089 TI - Social rank, observability, and sexual behaviour of rhesus monkeys (Macaca mulatta). PMID- 4206090 TI - Letter: Lymphoma and anticonvulsive therapy. PMID- 4206091 TI - Supraventricular arrhythmias caused by parenteral hyperalimentation. PMID- 4206092 TI - Absence of concurrent permeability changes of intestinal mucosa in association with cholera toxin-induced secretion. PMID- 4206093 TI - [Homozygous inherited alpha1-antitrypsin deficiency with emphysema of the lung, cor pulmonale, and gout (author's transl)]. PMID- 4206094 TI - [Influence of oxyphen butazon and cyclohexylpropionic acid on gastrointestinal blood loss (author's transl)]. PMID- 4206095 TI - Protein nutrition and liver disease after jejunoileal bypass for morbid obesity. PMID- 4206096 TI - Editorial: Somatostatin: newcomer from the hypothalamus. PMID- 4206097 TI - Letter: Asymptomatic gonorrhea in men. PMID- 4206098 TI - Letter: Range of normal serum magnesium values. PMID- 4206099 TI - Effect of thyrotropin releasing hormone (TRH) on the menstrual cycle in women. PMID- 4206101 TI - Amniotic fluid alpha-fetoprotein in anencephaly. PMID- 4206100 TI - Some thoughts on assessing the effectiveness of passive immunization to Rh. PMID- 4206102 TI - [Treatment of pneumonia with disodium-calcium versenate]. PMID- 4206103 TI - [Bacteriological and clinical aspects of the restoration of drug sensitivity of formerly resistant Mycobacterium cultures]. PMID- 4206104 TI - [Use of a modified Lowenstein-Jensen medium for the isolation of Mycobacterium tuberculosis from pathological material]. PMID- 4206105 TI - [Kanamycin dependence of Mycobacterium tuberculosis in a patient with fibro cavernous tuberculosis]. PMID- 4206106 TI - Evaluation of a latex agglutination test for amoebiasis. PMID- 4206107 TI - Immunization of monkeys against a recently isolated human strain of Trypanosoma rhodesiense by use of gamma irradiation. PMID- 4206108 TI - Antigenic variation in cyclically transmitted isolates of Trypanosoma gambiense. PMID- 4206109 TI - Immunoglobulins in bovine trypanosomiasis. PMID- 4206110 TI - Serum protein changes in trypanosomiasis in cattle. PMID- 4206111 TI - Experimental Trypanosoma cruzi infections in Erthrocebus patas. PMID- 4206112 TI - The capillary-tube agglutination (CA) test. A proposed aid for the diagnosis of trypanosomiasis in the field. PMID- 4206113 TI - Serological studies on strains of Trypanosoma vivax. PMID- 4206114 TI - Domestic risk factor--an attempt to assess risk of infection with Trypanosoma cruzi in houses in Brazil. PMID- 4206115 TI - The host selection pattern and infection rates of Panstrongylus megistus in an area of eastern Brazil. PMID- 4206116 TI - Isolation of a non-haemadsorbing strain of African swine fever (ASF) virus from a natural outbreak of the disease. PMID- 4206117 TI - Experimental Sarcoptes scabiei infection in pigs: clinical signs and significance of infection. PMID- 4206118 TI - Comparative studies on tomato aspermy and cucumber mosaic viruses. I. Physical and chemical properties. PMID- 4206119 TI - Prenatal screening in the serodiagnosis of blood group sensitization. PMID- 4206120 TI - Effect of heparin on the concentration of insulin in serum and plasma. PMID- 4206121 TI - Letter: Coagulation defects and arteriosclerosis in rabbits induced by diet containing triglycerides. PMID- 4206122 TI - Familial thyroxine-binding globulin deficiency. A study of three Danish families. PMID- 4206123 TI - Pathology of macroglobulinemia--a review of Japanese cases. PMID- 4206124 TI - Renal artery stenosis in childhood neurofibromatosis. PMID- 4206125 TI - A cephalometric evaluation of the old Milwaukee brace and the modified Milwaukee brace in relation to the normal growing child. PMID- 4206126 TI - Vaccination against Marek's disease with herpes virus of turkeys. PMID- 4206127 TI - Blood vessels of the ciliary ganglion in man. PMID- 4206129 TI - Outbreak of meningococcal disease in Devon. AB - In a recent outbreak of 31 cases of meningococcal disease in Devon there were six deaths. Several patients had an unusual rash as the presenting feature and there was an unusually high incidence of complications, affecting the central nervous system, joints, and the heart among other sites. PMID- 4206128 TI - Experience in monitoring gentamicin therapy during treatment of serious gram negative sepsis. AB - This paper reports our experience in monitoring gentamicin therapy during the treatment of 68 episodes of serious Gram-negative sepsis in 65 hospital patients. Most of the patients had major underlying disease. Of those who were adequately treated (peak serum concentrations of 5 mug/ml or more in 72 hours for septicaemia, urinary tract infection, and wound infection; and 8 mug/ml or more at some time during the course of treatment for pneumonia) 84% (46 out of 55) were cured. These serum concentrations could be achieved only by starting with a regimen of 5 mg/kg/day in three divided doses in all adult patients, subsequent dosage being determined by the results of rapid serum assay. The incidence of nephrotoxicity and symptomatic ototoxicity was no greater than in previous series. The main reason for assaying serum gentamicin is to ensure that an adequate dosage is achieved as soon as possible. In patients with impaired renal function or receiving prolonged high dosage assays also serve to guard against an excessive accumulation of gentamicin and an increased risk of toxicity. PMID- 4206130 TI - Letter: Clinical diagnosis of Reye's syndrome. PMID- 4206131 TI - Mechanism of the formation of concanavalin A-teichoic acid complexes. PMID- 4206132 TI - [The occurrence of cancer in diverticles of the wall of urinary bladder (author's transl)]. PMID- 4206134 TI - The possible site of action of sodium cromoglycate assessed by exercise challenge. PMID- 4206133 TI - Tissue distribution of coenzyme and other forms of vitamin B12 in control subjects and patients with pernicious anaemia. PMID- 4206135 TI - Field studies on the use of coated porous polyurethane plugs as indwelling monitors of organochlorine pesticides and polychlorinated biphenyl contents of streams. PMID- 4206136 TI - Evaluation of internal exposure to radionuclides of I, Cs and Co during maintenance operations on primary steam leak in a nuclear power station. PMID- 4206137 TI - The fetal uptake of cerium-144-praseodymium-144 after injection of its chelates to pregnant rat. PMID- 4206139 TI - Experimental amblyopia in monkeys. Further behavioral observations and clinical correlations. PMID- 4206138 TI - On prognosis and treatment of acute severe pancreatitis with severe uremia. PMID- 4206140 TI - Histological studies of the visual system in monkeys with experimental amblyopia. PMID- 4206142 TI - Fatty acid derivatives and glycolipids in high-protein bakery products. PMID- 4206141 TI - Soybean protein flavor components: a review. PMID- 4206143 TI - Neurophysiologic and behavioral toxicologic testing to detect subclinical neurologic alterations induced by environmental toxicants. PMID- 4206144 TI - Efferent connections of the red nucleus in the brainstem and spinal cord of the Rhesus monkey. PMID- 4206145 TI - Fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (Saimiri sciureus). IV. An atlas. PMID- 4206146 TI - A combined fluorescence histochemical and electron microscopic method for studying special monoamine-containing cells (SIF cells). PMID- 4206147 TI - The local antibody response to R.S. virus infection in the respiratory tract. AB - Nasopharyngeal secretions were taken during the acute phase of illness from 66 infants and children admitted to hospital with lower respiratory tract infections. Second secretions were taken, after an interval of 7 days, from 33 of these patients. A significant increase in neutralizing activity to R.S. virus was demonstrated in the nasopharyngeal secretions of patients in response to severe R.S. virus infection. Seventeen out of 25 patients (68%) with R.S. virus infections developed a rise in secretory neutralizing titre, compared with only 1 out of 8 patients (13%) with respiratory infections not involving R.S. virus.A high titre of secretory neutralizing activity was found more often in the acute phase of illness in patients with R.S. virus infections, especially bronchiolitis, than in patients with respiratory infections not involving R.S. virus. Fifteen out of 34 patients (44%) with R.S. virus bronchiolitis were found to possess a neutralizing titre of (1/4) or more in their first secretions, compared with 4 out of 12 patients (33%) with R.S. virus infections other than bronchiolitis and 3 out of 20 patients (15%) with respiratory infections not involving R.S. virus.A quantitative analysis of the immunoglobulins present in the secretions indicated that IgA was the only immunoglobulin consistently present at a detectable concentration. The geometric mean values of IgA, IgM and IgG in the secretions examined were found to be 22.3, 4.3 and 5.3 mg./100 ml. respectively.The neutralizing activity against R.S. virus, present in the secretions, was shown to be due to specific IgA antibody. This was accomplished by removing the neutralizing activity in two secretions by absorption with anti IgA serum. PMID- 4206148 TI - Effect of oral alanine on blood beta-hydroxybutyrate and plasma glucose, insulin, free fatty acids, and growth hormone in normal and diabetic subjects. PMID- 4206149 TI - Veterinary medicine and surgery in the Republic of Vietnam. PMID- 4206150 TI - The melena to admission time: a critical look at the patient with occult gastrointestinal bleeding. PMID- 4206151 TI - Conservation surgery of the larynx and hypopharynx. PMID- 4206152 TI - Acute epididymitis in Vietnam: review of 52 cases. PMID- 4206153 TI - Interface of dental research, federal and civilian. PMID- 4206154 TI - Case for diagnosis: a rapidly enlarging mass involving the right maxillary ridge. PMID- 4206155 TI - The bus case: earliest contact military psychiatry. PMID- 4206156 TI - An experimental evaluation of a therapeutic community. PMID- 4206157 TI - Regional perinatal health centers. PMID- 4206158 TI - A respirator development. PMID- 4206159 TI - Communication innovations at the mental hygiene consultation service-inpatient psychiatry interface. PMID- 4206161 TI - Murine typhus in Vietnam. PMID- 4206160 TI - Chemotherapeutic results in a multi-drug resistant strain of Plasmodium falciparum malaria from Vietnam. PMID- 4206162 TI - Coronary artery disease: its impact on Naval and Marine Corps personnel. PMID- 4206163 TI - The use of metronidazole in treating complications of amebiasis. PMID- 4206164 TI - Pemphigus-like antibodies in sera of patients with thermal burns, gunshot wounds, and skin grafts. PMID- 4206165 TI - Ultrasound and plantar warts: a double blind study. PMID- 4206166 TI - Lobo's disease involving the skin of a dolphin. PMID- 4206167 TI - Bradycardia tachycardia syndrome in a patient with a mitral prosthesis: case report. PMID- 4206168 TI - Arteriovenous malformations in Koreans. PMID- 4206169 TI - Alcoholism clinic in a military setting: a combined disulfiram and group therapy outpatient program. PMID- 4206170 TI - Parenteral hyperalimentation for severe postvagotomy gastric stasis: case report. PMID- 4206171 TI - Isolated Crohn's disease of the appendix: case report. PMID- 4206172 TI - One stage diagnosis and treatment of intrathoracic disease. PMID- 4206173 TI - Editorial: The hip osteotomy in orthopaedic surgery. PMID- 4206175 TI - Content of RNA polymerase in haploid and merodiploid strains of Escherichia coli. PMID- 4206174 TI - Dosage compensation of sex-linked genes in Drosophila melanogaster. The activities of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in flies with normal and disturbed genetic balance. PMID- 4206176 TI - [Hypoglycemia caused by oral antidiabetic agents]. PMID- 4206177 TI - [Decrease of unconsciousness and hypophosphatemia in intravenous feeding]. PMID- 4206178 TI - The diagnosis of bovine mastitis: a critical evaluation of a polyvalent radial immunodiffusion test and other methods. PMID- 4206179 TI - Locomotor body equilibrium after diazepam injection in the squirrel monkey. PMID- 4206180 TI - Combined radiotherapy and chemotherapy in the treatment of Hodgkin's disease. PMID- 4206181 TI - Use of serial exercise tests to assess the efficacy and duration of action of drugs for asthma. PMID- 4206183 TI - Metabolism of synthetic steroids by animals and man. PMID- 4206182 TI - [Ascite tuberculous peritonitis in the aged patient. Apropos of pseudoneoplastic forms]. PMID- 4206184 TI - Teratogenic screening methods and their application to contraceptive products. PMID- 4206185 TI - U.S. Food and Drug Administration requirements for toxicity testing of contraceptive products. PMID- 4206186 TI - Design of early clinical trials for new contraceptive methods. PMID- 4206187 TI - Special requirements for plastic devices. PMID- 4206189 TI - Special requirements for testing post-coital contraceptives. PMID- 4206188 TI - Special problems in toxicity testing of long acting depot contraceptives. PMID- 4206190 TI - Special requirements for testing spermicides. PMID- 4206191 TI - Special requirements for toxicity testing of oral compounds administered continuously or cyclically. PMID- 4206192 TI - Special requirements for toxicological testing of metal-releasing intrauterine devices. PMID- 4206193 TI - Special toxicology for the prostaglandins. PMID- 4206194 TI - Absorption and elimination of polychlorinated biphenyls (PCB) in goldfish. PMID- 4206195 TI - Regional variation in the presence of mast cells in the mammalian brain. PMID- 4206196 TI - On the phenomenon of the two linear Hammett relationships: its origin and its use as a tool in the analysis of diamine oxidase preparations. PMID- 4206197 TI - Muscular subaortic stenosis and Friedreich's ataxia. PMID- 4206198 TI - Placental CO2 transfer after fetal carbonic anhydrase inhibition. PMID- 4206199 TI - The similarities of optokinetic after-nystagmus to the vestibular nystagmus. PMID- 4206200 TI - Quantitative determination of secretory immunoglobulin A (SIgA) in middle ear effusions. PMID- 4206201 TI - Immunological identification of nascent subunits of wheat ribulose diphosphate carboxylase on ribosomes of both chloroplast and cytoplasmic origin. PMID- 4206202 TI - Hyaluronidase and esterase activities of the venom of the poisonous brown recluse spider. PMID- 4206203 TI - A rat liver protein with potential thrombin activity: properties and partial purification. PMID- 4206204 TI - Physiological correlates of auditory stimulus periodicity. PMID- 4206205 TI - Structural and physiological features of the organ of Corti. PMID- 4206206 TI - Mechanocardiography and hemodynamics. PMID- 4206207 TI - Hemodynamic stress and relief of the heart in the light of comparative physiological investigations. PMID- 4206208 TI - Early diagnosis of arterial atherosclerosis by means of resonance electrosphygmography. PMID- 4206209 TI - Facilitation of Fe(II) autoxidation by Fe(3) complexing agents. PMID- 4206210 TI - The storage and manipulation of radiation dose data in a small digital computer. PMID- 4206211 TI - Letter: A rapid method for the determination of tumour RBE. PMID- 4206212 TI - Dwarfism in the newborn: the nomenclature, radiological features and genetic significance. PMID- 4206213 TI - Ossifying lipoma. PMID- 4206214 TI - Penicillin treatment of gonorrhoea in Edinburgh. PMID- 4206215 TI - Absence of chlorinated dibenzodioxins and dibenzofurans from aquatic animals. PMID- 4206216 TI - Polychlorinated biphenyls (PCB) in sea water and their effect on reproduction of Gammarus oceanicus. PMID- 4206217 TI - Allergy to snake venom: the use of radioimmunoassay for the detection of IgE antibodies against antigens not suitable for cutaneous tests. PMID- 4206218 TI - Uptake of disodium cromoglycate in obstructive airways disease. PMID- 4206219 TI - The effect of frequent administration of sodium cromoglycate to asthmatic children who previously responded poorly. PMID- 4206220 TI - Hypersensitivtiy responses in monkeys. VI. P-K, histamine, 48-80 responses after challenges with heterologous antigen or the other agents. PMID- 4206221 TI - [New viewpoints on the treatment of toxoplasmosis]. PMID- 4206223 TI - [A case of association of hemoglobin D-beta microcythemia]. PMID- 4206222 TI - [Polarographic analysis of titanium]. PMID- 4206225 TI - [The mechanism of extrarenal production of erythropoietin]. PMID- 4206224 TI - [Pathogenesis of pure red cell aplasia associated or not associated with thymoma]. PMID- 4206226 TI - [Relationship between the renal erythropoietic factor and plasma erythropoietin]. PMID- 4206228 TI - [Inhibition of hypoxic erythropoietin production after treatment with microdoses of estradiol benzoate]. PMID- 4206227 TI - [Biosynthesis of erythropoietin: presence of an hypoxic plasma factor activating the renal erythropoietic factor]. PMID- 4206229 TI - [Pure red cell aplasia associated with thymoma. Demonstration of an autoimmune serum factor inhibiting erythropoiesis and remission induced by cyclophosphamide]. PMID- 4206230 TI - [Myeloaplastic preleukemic syndromes. A propos of 3 cases]. PMID- 4206231 TI - [Liver glycogen in patients with congenital hemolytic anemia with an erythrocyte defect]. PMID- 4206232 TI - [Histopathological aspects of the spleen in patients with essential thrombocytopenia]. PMID- 4206233 TI - [Blood coagulation disorder in a 7-year-old child with a partial factor X or Stuart-Prower factor deficiency]. PMID- 4206234 TI - [Histocytological and chromosome studies in a case of chronic histiocytic leukemia]. PMID- 4206236 TI - [Effect of actinomycin D on the erythropoiesis of the newborn rat]. PMID- 4206235 TI - [Preliminary studies on the effectiveness of the association cytosine arabinoside, thioguanine, hydroxyureas in the treatment of blastic crisis in chronic myeloid leukemia]. PMID- 4206237 TI - [Urinary iron after desferrioxamine. I. Effectiveness and tolerance of high doses of the drug]. PMID- 4206238 TI - [Hereditary macrothrombocytic thrombocytopenia. Description of a family carrying this anomaly]. PMID- 4206239 TI - [Semiautomatic study of platelet aggregation]. PMID- 4206240 TI - An overview of the mycotoxicoses of domestic animals. PMID- 4206242 TI - Proceedings: Serum amylase and related enzymes in diabetic ketoacidosis. PMID- 4206241 TI - Superiority of simplified assay for folate with Lactobacillus casei ATCC 7469 over assay with chloramphenicol-adapted strain. AB - Direct assay of serum folate by mixing serum with a mixture of L. casei and medium without autoclaving was found to provide serum folate results similar to those by extraction of serum with heat. This procedure was found more reliable than that using the same technique with chloramphenicol and a strain of L. casei adapted to grow in this material. A portion of apparent folate activity assayed in haemolysates by such direct assay was found to be due to material other than folate. It is recommended that heat extraction of haemolysates be continued for determination of whole blood folate, or that an additional standardization of technique be included if direct assay is used. PMID- 4206243 TI - Echocardiographic M-scan technique in the diagnosis of pericardial effusion. PMID- 4206244 TI - DEAE-cellulose chromatography: a method for dissociation of soluble immune complexes of hepatitis B antigen. PMID- 4206245 TI - Reaction mechanisms of nascent C567 (reactive lysis). II. Killing of a rough form of Escherichia coli by C567, C8, and C9. PMID- 4206246 TI - An immunologic model in laboratory animals for the study of Neisseria gonorrhoeae. PMID- 4206247 TI - Characterization of brain-associated rabies neutralizing substance. PMID- 4206248 TI - Pharmacokinetics of ampicillin in the newborn infant. PMID- 4206249 TI - Protective effect of pyocin against lethal Pseudomonas aeruginosa infections in mice. PMID- 4206250 TI - The effect of chemotherapy for tuberculosis on immunity to tuberculosis. PMID- 4206252 TI - [Basic studies for the determination of reasonable levels of ambition]. PMID- 4206251 TI - [Geriatric treatment in Goteborg]. PMID- 4206253 TI - [The great importance of long term care for necessary rehabilitation resources]. PMID- 4206254 TI - On the control of cholesterol synthesis. PMID- 4206255 TI - Management of stable angina. PMID- 4206256 TI - Microbes. 4. Robert Koch: anthrax bacilli isolated. PMID- 4206257 TI - Studies in head injury. I. An experimental model of closed head injury. PMID- 4206258 TI - Studies in head injury. II. Effect of dexamethasone on traumatic brain swelling. PMID- 4206259 TI - [Blood serum bactericidal activity of chronic typhoid-paratyphoid carriers in relation to autostrains]. PMID- 4206260 TI - [Methodological and organizational aspects of detecting chronic carriers of typhoid and paratyphoid bacteria (review of the literature in 1960-1971)]. PMID- 4206261 TI - [Mechanism of immunogenesis during vaccination with streptomycin-dependent mutants of salmonellae and shigellae. V. Dynamics of antibody-producing cells in monkey lymphoid tissue]. PMID- 4206262 TI - [Comparative serological analysis of soluble antigens of group A meningococci]. PMID- 4206263 TI - The synthesis of fat and water soluble arseno organic compounds in marine and limnetic algae. PMID- 4206264 TI - RNA synthesis in the uterine epithelium stimulated by estrogen injection. PMID- 4206265 TI - [Histochemical evidence of alcohol dehydrogenase in liver sections (author's transl)]. PMID- 4206266 TI - [The representation of plant tissues after freeze substitution with special reference to the structural preservation of plastids (author's transl)]. PMID- 4206267 TI - [Use of the complex-forming agent Tiron in the histochemical demonstration of NaK ATPase activity]. PMID- 4206268 TI - Uptake and hydrolysis of 131-I-albumin in the toad liver. The effect of low body temperature. PMID- 4206269 TI - Cultivation of animal cells in chemically defined media, a review. PMID- 4206270 TI - Isoelectric fractionation of sulfated glycoproteins on polytetrafluoroethylene coated columns. PMID- 4206271 TI - Specific tlc, gc, and gc-ms methods for kinetic studies with COMT. PMID- 4206273 TI - Flexibacteria. PMID- 4206272 TI - Differentiation of DNA and RNA on filter paper discs. PMID- 4206274 TI - Amidase activity of human alpha-macroglobulin. PMID- 4206275 TI - Inhibition of growth of transplantable melanotic melanoma in golden hamsters (Mesocricetus auratus, Waterhouse) by chlorpromazine. PMID- 4206277 TI - [Tube feeding in operations on the upper digestive tract (author's transl)]. PMID- 4206276 TI - Inhibiting effect of chloroquine diphosphate on the growth of tumors and activity of some acid hydrolases of a melanotic melanoma in golden hamsters (Mesocricetus auratus, Waterhouse). PMID- 4206278 TI - A new case of IgD-myeloma associated with hypogammaglobulinemia. PMID- 4206279 TI - [The importance of dogs and cats in the epidemiology of Chagas disease (author's transl)]. PMID- 4206280 TI - [Diphtheria. Its incidence in Senegal]. PMID- 4206281 TI - [Australia antigen in Dahomey]. PMID- 4206283 TI - [Australia antigen and hepatic diseases (experience in Saint Louis)]. PMID- 4206282 TI - [Treatment of cerebral malaria with a fansidar-hydergine combination]. PMID- 4206285 TI - Reaching in light and dark after unilateral posterior parietal ablations in the monkey. PMID- 4206284 TI - Evaluation of lidoflazine as an anti-anginal drug. PMID- 4206286 TI - An international survey on nutrition and pancreatitis. PMID- 4206287 TI - Developmental studies on some enzymes associated with 'detoxication'. PMID- 4206288 TI - [Determination of biological hazards of water polluting substances from the inhibition of glucose assimilation of the bacterium Pseudomonas fluorescens]. PMID- 4206289 TI - [Rh-sensitization of newborn infants through dissonant materno-fetal transfusion]. PMID- 4206290 TI - Careful presentation of evidence helps clear hospital. PMID- 4206291 TI - The CHSLP financial model. PMID- 4206292 TI - The use of a whole body counter for measuring bone marrow erythroid activity by profile scanning. PMID- 4206293 TI - Recent advances in whole-body counting: a review. PMID- 4206295 TI - Effects of microsporidan infection on larval trematodes: infection with Nosema strigeoideae or N. echinostomi. PMID- 4206296 TI - The etiological agent of cytoplasmic incompatibility in Culex pipiens. PMID- 4206297 TI - The infection of nonmosquito hosts by injection with spores of the microsporidan Nosema algerae. PMID- 4206298 TI - High energy x-ray therapy of gastric carcinoma. PMID- 4206299 TI - An electron microscopic study of the neurons of the primate motor and somatic sensory cortices. PMID- 4206300 TI - An electron microscope study of the termination of afferent connections to the primate motor cortex. PMID- 4206301 TI - Advantages and limitations of radioisotope clearance methods from a clinician's point of view. PMID- 4206303 TI - Preparation and use of benzhydrylamine polymers in peptide synthesis. II. Syntheses of thyrotropin releasing hormone, thyrocalcitonin 26-32, and eledoisin. PMID- 4206302 TI - Renal clearance investigation with radionuclides. PMID- 4206304 TI - The importance of routine urine culture in malnourished children. PMID- 4206305 TI - Nutritional problems of children in new urban families. PMID- 4206306 TI - Pediatric surgery. 1. PMID- 4206307 TI - Adrenal regulation of protein synthesis in protein malnutrition. PMID- 4206308 TI - [Changes in protein components of semen plasma from bulls with inflammatory diseases of the testes]. PMID- 4206309 TI - [Isolation and purification of asparaginase from various sources and study of its activity]. PMID- 4206310 TI - Present day management and treatment of Hodgkin's disease. PMID- 4206311 TI - [Recent data on Australia antigen]. PMID- 4206312 TI - [Detection of pulmonary tuberculosis in the rural areas of Algeria. Apropos of 2 recent surveys (Boufarik, 1970 and Kolea, 1972)]. PMID- 4206313 TI - [Development of tuberculous meningitis in Algeria, 1967-1972]. PMID- 4206314 TI - [Diagnosis and treatment of Pott's disease. Apropos of 183 cases]. PMID- 4206315 TI - [Tuberculosis of the foot and of the top of the foot]. PMID- 4206317 TI - Aphakia and multiple ocular defects in Saint Bernard puppies. PMID- 4206316 TI - [Tuberculous osteitis]. PMID- 4206318 TI - [Tracheal abnormalities and their surgery]. PMID- 4206319 TI - [Methods and value of the microbiological diagnosis of urogenital tuberculosis]. PMID- 4206320 TI - Content of beta-2-microglobulin and albumin in human amniotic fluid. A study of normal pregnancies and pregnancies complicated by haemolytic disease. PMID- 4206321 TI - Isolation and identification of Corynebacterium vaginale (Haemophilus vaginalis) in women with infections of the lower genital tract. PMID- 4206322 TI - Effect of oral contraceptives on the plasma concentration of pyridoxal phosphate. PMID- 4206323 TI - Isolation of Candida species from the gastrointestinal tract in malnourished children. PMID- 4206324 TI - Intestinal absorption of D-xylose and folic acid in protein-deficient patas monkeys (Erythrocebus patas). PMID- 4206326 TI - Amino acid compositions of the tryptic peptides comprising the beta-hemoglobin chain of Macaca nemestrina. PMID- 4206325 TI - Multiple fetal and adult hemoglobins in Malaysian Macaca nemestrina: consequences of a-chain variation. PMID- 4206327 TI - Behavior of an all-juvenile group of Rhesus monkeys. PMID- 4206328 TI - Sharing of Cercarienhullen Reaktion antigens between Schistosoma mansoni cercariae and adults and uninfected Biomphalaria pfeifferi. PMID- 4206329 TI - Ecology of viruses isolated from Panamanian phlebotomine sandflies. PMID- 4206330 TI - Childhood pigeon breeder's disease. PMID- 4206331 TI - Simian gastropathy with submucosal glands and cysts. Gastritis glandularis or cystica profunda? PMID- 4206332 TI - [Transfer factor and its therapeutic significance]. PMID- 4206333 TI - [Separation of complete (IgM) and incomplete (IgM) antibody activities in blood group specific antisera using gel chromatography]. PMID- 4206334 TI - Effects of nitroglycerin on left ventricular wall motion in coronary artery disease. PMID- 4206335 TI - The analysis of the effects of early experiences. PMID- 4206336 TI - Dynamics of spermiogenesis in Drosophila melanogaster. 3. Relation between axoneme and mitochondrial derivatives. PMID- 4206337 TI - Comparative growth characteristics of VERO cells on gas-permeable and conventional supports. PMID- 4206338 TI - DNA synthesis following refeeding of starved Tetrahymena pyriformis GL: starved cells are arrested in G 1. PMID- 4206339 TI - A convenient method for enucleating cells in quantity. PMID- 4206340 TI - Perivascular hemorrhagic lesions in temporal cortex following cerebral infarction (a morphological study). PMID- 4206341 TI - The chemical composition and ultrastructure of the cell wall of Scenedesmus obliquus. II. Amino acids, proteins and antigens. PMID- 4206342 TI - Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural cholera toxoid. AB - The in vitro binding properties of enterotoxins of Vibrio cholerae and Escherichia coli to different pure gangliosides and related neutral glycosphin golipids were analyzed with a sorbent assay utilizing plastic tubes to which the glycolipid substances had been coupled. It was found that the cholera toxin bound to G(M1) ganglioside better than to the other tested substances G(M3), G(M3)-NGN, G(M2), G(D1a), G(D1b), G(T), G(A1), tetrahexoside-GlcNac and globoside. With this assay using G(M1)-coated tubes it is possible to measure cholera toxin even at concentrations below 1 ng/ml. Also enterotoxin of various E. coli strains bound to G(M1), but the affinity was much less than for cholera toxin. The G(M1) ganglioside, in contrast to the other glycosphingolipids, effectively inactivated cholera toxin as determined with the intradermal and the ileal loop assays; approximately equimolar concentrations of the ganglioside in relation to toxin sufficed. Also, the skin and ileal loop activities of E. coli enterotoxins could be inhibited by G(M1); however, several orders more of the ganglioside were required for such inhibition than for inactivation of the cholera toxin, and the differences between G(M1) and the other substances were less pronounced for E. coli toxins. Preincubation of rabbit ileal loops with choleragenoid, a natural toxoid of V. cholerae which has binding properties to the G(M1) ganglioside similar to cholera toxin, made the loops resistant to subsequently added enterotoxin of V. cholerae. The responsiveness to enterotoxin of E. coli was not reduced by this toxoid. A likely interpretation of these data is that the G(M1) ganglioside constitutes or at least contains the structure of functional tissue receptors for the cholera toxin, whereas the weak binding to G(M1) by E. coli enterotoxins is probably a pathogenetically insignificant reflection of structural similarities between these toxins and cholera toxin. Consequently, the cholera toxoid by occupying functional intestinal G(M1) receptors for the cholera toxin could inhibit the ileal response to this toxin, but not the response to E. coli enterotoxin since the intestinal receptors for the latter toxin are not affected by the cholera toxoid. PMID- 4206343 TI - Pathogenicity and immunogenic efficacy of a live attentuated plaque vaccine in vervet monkeys. AB - A live attenuated Yersinia pestis (Pasteurella pestis) vaccine strain designated EV51f, which had been passaged through guinea pigs previously treated with ferrous sulfate, was shown to be pathogenic for African green vervet monkeys (Cercopithecus aethips pygerythrus), but not for guinea pigs. The bacilli multiplied in the monkeys, as shown by positive blood cultures, caused an elevation of white cell counts and rectal temperatures, and resulted in death of 26% (13/50) of animals. Postmortem findings of these animals were typical of bubonic-septicemic plague. This vaccine did not cause deaths in 50 guinea pigs even in doses up to 100 million viable bacilli inoculated subcutaneously. It is suggested that the virulence of an attenuated Y. pestis strain which does not produce pigment on a defined medium containing hemin, but possesses all other known virulence determinants, is dependent on the availability of iron in vivo. The serological response of the monkeys as determined by the hemagglutinating and mouse protective antibodies was high one month after vaccination and also in guinea pigs, as shown by virulent challenge. This antibody level declined in monkeys over a period of nearly 6 months, and a decline in immunity was confirmed by virulent challenge which resulted in the death of 30% of vaccinated monkeys. The level of immunity in monkeys did not appear to be related to the dose of vaccine. PMID- 4206344 TI - Immunological studies on the envelope component of Venezuelan equine encephalomyelitis virus. AB - Treatment of purified Venezuelan equine encephalomyelitis virus with the nonionic detergent Triton X-100 permitted spearation of the envelope from the core component. The isolated envelope was a noninfectious immunogen which reacted in hemagglutination, hemagglutination inhibition, complement fixation, and neutralization serological reactions. PMID- 4206345 TI - Pathogenesis and immunology of experimental gonococcal infection: virulence of colony types of Neisseria gonorrhoeae for chicken embryos. AB - The virulence of gonococcal strains and colony types was evaluated in embryonated hen eggs of various ages inoculated by different routes. Striking differences in virulence of colony types were revealed by intravenous inoculation of 11-day embryos. T1 and T2 colony types were found to have high virulence for embryos, whereas T3 and T4 colony types were relatively avirulent. These observations are in accord with previous studies in volunteers. The differences in virulence were not related to differences in toxicity of killed gonococci, sonic lysates, or to the susceptibility of gonococci to cidal effects of chicken embryo blood. Rather, they appeared to involve differences in clearance of gonococci from the blood stream and subsequent multiplication of the virulent colony types. Infection with virulent colony types appears to be primarily bacteremic in this model. Preliminary experiments indicated that chicken embryos may be protected against the lethal infection by prior treatment of the inoculum with normal and immune rabbit serum. This protective effect was not associated with bactericidal activity. The chicken embryo model is potentially useful as a means of investigating attributes of virulence of gonococci and factors in immunity against gonorrhea. PMID- 4206346 TI - Contact sensitivity in vitro: activation of actively allergized lymphocytes by a beryllium complex. PMID- 4206347 TI - Structure and biological functions of human IgD. 3. Phylogenetic studies of IgD. PMID- 4206348 TI - Isolation of a low molecular weight ragweed pollen allergen: Ra5. PMID- 4206349 TI - A study of immunoglobulins in jejunal secretion and serum of patients suffering from Mediterranean cirrhosis. PMID- 4206350 TI - Regulation of lipogenesis and the total activities of lipogenic enzymes in a primary culture of hepatocytes from prenatal and early postnatal chicks. PMID- 4206351 TI - Purification of ribonucleic acid polymerase from SP82-infected Bacillus subtilis. PMID- 4206352 TI - In vivo and in vitro transcription by ribonucleic acid polymerase from SP82 infected Bacillus subtilis. PMID- 4206353 TI - Recognition of primary sequence variations among sperm whale myoglobin components with successive proteolysis procedures. PMID- 4206354 TI - A mammalian endonuclease specific for apurinic sites in double-stranded deoxyribonucleic acid. I. Purification and general properties. PMID- 4206355 TI - Preparation and prolonged tissue retention of liposome-encapsulated chelating agents. PMID- 4206356 TI - Three isoaccepting forms of leucyl transfer RNA in mitochondria. PMID- 4206357 TI - Cerebral circulation and metabolism. Summary of International Symposium, June 6 10, 1973. PMID- 4206358 TI - Identification of blood meals of sandflies (Diptera: psychodidae). PMID- 4206359 TI - Long term effects of aflatoxin B1 and viral hepatitis on marmoset liver. A preliminary report. PMID- 4206360 TI - Ultrastructural changes in the liver of baboons following lead and endotoxin administration. PMID- 4206361 TI - Mechanism of denaturation of haemoglobin by alkali. PMID- 4206362 TI - Intra- and interpopulation selection concerning the alcohol dehydrogenase locus in Drosophila melanogaster. PMID- 4206363 TI - Nitrosocarbaryl as a potent mutagen of environmental significance. PMID- 4206365 TI - Therapeutic value of local perfusion for acute spinal cord trauma. PMID- 4206364 TI - [Disinfectants and their use in dental offices]. PMID- 4206366 TI - In vivo measurement of cerebral glucose metabolism employing 11C-labeled glucose. PMID- 4206367 TI - Impaired tool-using behavior in monkeys from bilateral destruction of the dorsomedial nuclei of the thalamus. PMID- 4206368 TI - Clinical grade, regional cerebral blood flow, and angiographical spasm in the monkey after subarachnoid hemorrhage. PMID- 4206369 TI - The effect of chronic cerebellar stimulation upon epilepsy in man. PMID- 4206370 TI - Magnocellular neuroendocrine cells in the monkey hypothalamus. PMID- 4206371 TI - The modification of L-dopa induced dyskinesias in the monkey by unilateral nigral lesions. PMID- 4206372 TI - Experimental tremor following CNS lesions in monkeys. PMID- 4206373 TI - Physiopathological study in monkeys with partial and complete destruction of cerebellar structures. PMID- 4206374 TI - Some new observations on intracerebellar nuclei: their participation in patterned movements. PMID- 4206375 TI - "Triadic" synapses and other articulations of interneurons in the lateral geniculate nucleus of rhesus monkeys. PMID- 4206376 TI - Petit mal status presenting as psychasis. PMID- 4206377 TI - Cerebellopontine influence on the motor system: a functional and anatomical study following section of the brachium pontis in trained macaque monkeys. PMID- 4206378 TI - Visual inhibition of nystagmus by the flocculus. PMID- 4206379 TI - Abnormal drug metabolism in rats after an inflammatory insult. PMID- 4206380 TI - The prophylactic and therapeutic effects of gold sodium thiomalate against adjuvant-induced polyarthritis in rats. PMID- 4206381 TI - Esophageal surgery: a procedure for posterior invagination esophagogastrostomy in one-stage without positional change. PMID- 4206382 TI - Surgical management of carcinoma of the maxilla. PMID- 4206383 TI - [Worsening of epilepsies under treatment]. PMID- 4206384 TI - [West's syndrome developing into Lennox-Gastaut syndrome in a patient with cerebral cysticercosis]. PMID- 4206386 TI - Causes of death in irradiated adult insects. PMID- 4206385 TI - Urinary excretion in the rat of nifurpipone (NP) and of nitrofurantoin (NTF) administered by different routes. PMID- 4206387 TI - Response pattern complexity of auditory cells in the cortex of unanesthetized monkeys. PMID- 4206388 TI - [Effects of primary and secondary cosmic radiation on the development and longevity of Drosophila melanogaster]. PMID- 4206389 TI - [First experiments on tarsal gustation in Drosophila melanogaster: stimulation with sucrose]. PMID- 4206390 TI - The inactivation by carbenoxolone of individual human pepsinogens and pepsins. PMID- 4206391 TI - Transfer factor--fact or fiction? PMID- 4206392 TI - GM1-gangliosidosis. I. Clinical aspects and biochemistry. PMID- 4206393 TI - Effect of diphenylhydantoin on insulin response in the oral glucose tolerance test in children and adolescents. PMID- 4206395 TI - Restraint and anesthesia in zoo animal practice. PMID- 4206394 TI - Sorbitol in total parenteral nutrition in pediatric patients. PMID- 4206396 TI - Pentastoma larvae in a squirrel monkey. PMID- 4206397 TI - Pulmonary pathology in stillborn nonhuman primates. PMID- 4206398 TI - Persistent pupillary membranes in a rhesus monkey. PMID- 4206399 TI - Candida albicans infections associated with antibiotic and corticosteroid therapy in spider monkeys. PMID- 4206400 TI - Detection of isoniazid in urine and blood serum of nonhuman primates. PMID- 4206401 TI - Alpha-ketoglutaric semialdehyde dehydrogenase of Pseudomonas. Properties of the separately induced isoenzymes. PMID- 4206402 TI - An alpha-D-galactosyl-binding lectin from Bandeiraea simplicifolia seeds. Isolation by affinity chromatography and characterization. PMID- 4206403 TI - Nutritional study of three strains of Naegleria gruberi. PMID- 4206404 TI - Kudoa cerebralis sp. n. (Myxosporidea, Chloromyxidae) from the striped bass, Morone saxatilis (Walbaum). PMID- 4206405 TI - Microsporidian parasites of trematode larvae from aquatic snails in West Malaysia. PMID- 4206406 TI - Three avenues to ecologic research on parasitic protozoa. PMID- 4206407 TI - Rumen ciliate fauna of Alaskan moose (Alces americana), musk-ox (Ovibos moschatus) and Dall moutain sheep (Ovis dalli). PMID- 4206408 TI - Pollution. PMID- 4206410 TI - Reproductive failure and mortality in mink fed on Great Lakes fish. PMID- 4206409 TI - Effects of PCB and DDE in cormorants and evaluation of PCB residues from an experimental study. PMID- 4206411 TI - The role of pheromones in the social communication of marmoset monkeys (Callithricidae). PMID- 4206412 TI - On the fine structure of the acidophilic hot-spring alga Cyanidium caldarium: a taxonomic approach. PMID- 4206413 TI - Obstruction of the common bile duct. Duodenal diverticula. PMID- 4206414 TI - [Functional electrocardiography for professional practice]. PMID- 4206415 TI - [Atrial stimulation in the therapy of auricular flutter]. PMID- 4206416 TI - [Proposal for the therapy of myocardial infarct in its initial stage]. PMID- 4206417 TI - [Is direct puncture always necessary in the diagnosis of cerebral vascular disease]. PMID- 4206418 TI - [Adverse effects of contraceptive steroids]. PMID- 4206419 TI - [Accidents in the water and on ice]. PMID- 4206420 TI - [Antihypertensive effect of verapamil. Studies on and experiences with children]. PMID- 4206421 TI - [Therapeutic experiences with Nortensin in the therapy of hypertension due to pregnancy]. PMID- 4206422 TI - [Therapy of enuresis nocturna using the special preparation Noxenur]. PMID- 4206423 TI - [Delayed type hypersensitivity--production of MIF and developement of reaction (author's transl)]. PMID- 4206425 TI - [Cytopathogenic effect of the Schwarz strain measles virus on chick embryo cell cultures]. PMID- 4206424 TI - [Subnutrition and protein-calorie malnutrition in the underdeveloped regions of the world. Epidemiological study and prevention]. PMID- 4206426 TI - Feto-maternal production and transfer of cortisol in the rhesus (Macaca mulatta). PMID- 4206427 TI - Quantification of 20alpha- and 20beta-dihydroprogesterone in plasma of the pregnant rhesus monkey. PMID- 4206428 TI - [Morphological regularity of the evolution of the brain]. PMID- 4206429 TI - A comparison of vocalizations of red-tailed monkeys and blue monkeys, Ceropithecus ascanius and C. mitis, in Uganda. PMID- 4206430 TI - [Studies on self-recognition in a mirror in orang-utans, chimpanzees, gibbons and various other monkey species]. PMID- 4206431 TI - [Behavior and orientation]. PMID- 4206432 TI - Effects of intensity on the phototactic responses of adult anuran amphibians: a comparative survey. PMID- 4206433 TI - [Tuberculin tests in sanatorium pediatry (author's transl)]. PMID- 4206434 TI - [Tuberculin tests in pediatric hospital practice (author's transl)]. PMID- 4206435 TI - [Classification and clinical significance of non tuberculous mycobacteria (author's transl)]. PMID- 4206436 TI - [The atypical mycobacteria studied in 1969 and 1970 (author's transl)]. PMID- 4206437 TI - [Currently used laboratory methods for testing the sensitivity and resistance of mycobacteria to drugs. Usefulness and limitations (author's transl)]. PMID- 4206438 TI - [Place of bacteriological examination in the treatment of tuberculosis]. PMID- 4206439 TI - [Precipitins against aspergilli. Significance and clinical interest (author's transl)]. PMID- 4206440 TI - [Action of ethambutol and rifampicin on the phagocyted mycobacterium by alveolar macrophage (author's transl)]. PMID- 4206441 TI - Rifampicin: a first line tuberculostatic drug. A critical review and appraisal. PMID- 4206442 TI - Beneficial electrophysiologic effects of nitroglycerin during acute myocardial infarction. PMID- 4206443 TI - Nitroglycerin-induced reduction in the incidence of spontaneous ventricular fibrillation during coronary occlusion in dogs. PMID- 4206444 TI - Ocular side-effects of oral contraceptives. PMID- 4206445 TI - Minimizing systemic infection during complete parenteral alimentation of small infants. PMID- 4206446 TI - [Purification and physiochemical, chemical and biological properties of a toxic A2 phospholipase isolated from the venom of viperidae snakes: Vipera berus]. PMID- 4206447 TI - Electric birefringence of native DNA in an alternating field. PMID- 4206448 TI - [Anatomo-histological research on experimental esophagitis induced in rabbits with high-energy radiations]. PMID- 4206449 TI - [Kinetics of incorporation of thymidine-H3 in cell cultures infected with rubella virus]. PMID- 4206450 TI - Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia. PMID- 4206452 TI - Standardization of diagnostic materials. 5. Tissue culture media and reagents. AB - The various factors that affect the growth of cell cultures in vitro are considered and suggestions are made as to where the standardization of components would help to provide more uniform products. The manufacture of powdered media in bulk and the establishment of cell banks have been major advances, but much research is needed for the standardization or replacement of serum. PMID- 4206451 TI - A controlled field trial of a serogroup A meningococcal polysaccharide vaccine. AB - A controlled field trial of a serogroup A meningococcal polysaccharide vaccine was conducted at three locations in Egypt during the winter cerebrospinal meningitis (CSM) season of 1971-72. The study population consisted of schoolchildren 6-15 years of age. No cases of serogroup A meningococcal CSM occurred in the group of students vaccinated with the test vaccine whereas 8 cases occurred in the control group vaccinated with tetanus toxoid, and 151 cases occurred in an unvaccinated contrast group. The case rate was significantly different between the test and control groups as well as between the test and contrast groups but was similar between the control and contrast groups. The previously demonstrated safety of the vaccine was confirmed. A significant serological response was elicited in the majority of the vaccinated students. PMID- 4206453 TI - [Giant duodenal diverticulum and annular pancreas]. PMID- 4206454 TI - [Diverticulum of the posterior surface of the gastric fornix]. PMID- 4206455 TI - Polymer enhancement of automated immunological nephelometric analysis, as illustrated by determination of urinary albumin. PMID- 4206456 TI - Transport of 5-methyltetrahydrofolic acid into the cerebrospinal fluid in man. PMID- 4206457 TI - [Faulty haemoglobin values in Sia-positive Waldenstrom's macroglobulinaemia (author's transl)]. PMID- 4206458 TI - Genetic control of quantitative variation in self-incompatibility proteins detected by immunodiffusion. AB - Single radial immunodiffusion was used to study the self-incompatibility (S) proteins present in stigmas of two inbred lines of Brassica oleracea: a self incompatible line and a self-compatible mutant derived from it. The genetic basis of observed quantitative differences in S proteins between the two inbreds was shown to be determined by a single gene with dosage effects. Self-pollination of individual plants with high, intermediate and low levels of S protein in the stigmas, respectively, resulted in low, intermediate and high seed set. PMID- 4206459 TI - A new mutant controlling mitotic chromosome disjunction in Drosophila melanogaster. AB - A new mutant, mit (mitotic loss inducer), is described. The mutant is recessive and maternal in action, producing gynandromorphs and haplo-4 mosaics among the progeny of homozygous mit females. Mosaic loss of maternal or paternal chromosomes can occur. The probabilities of either maternal or paternal X chromosome loss are equal. mit has been mapped to approximately 57 on the standard X chromosome map.-Using gyandromorphs generated by mit, a morphogenetic fate map, placing the origins of 40 cuticular structures on the blastoderm surface, has been constructed. This fate map is consistent with embryological data and with the two other fate maps generated in different ways. PMID- 4206460 TI - The effect of phenobarbital on cholesterol gallstones in hamsters. AB - This experimental study was undertaken to follow the influence of phenobarbital on bile chemistry and gallstone formation. Phenobarbital (400 mg/kg/day) was administered to golden hamsters receiving a diet known to induce cholesterol gallstones. After a 28-day period none of the control animals had gallstones whereas five of 12 animals with added phenobarbital developed stones. Ten of 19 animals on the lithogenic diet formed gallstones but when phenobarbital was added gallstones occurred in 16 of 19 hamsters. The administration of phenobarbital resulted in the production of bile which was relatively more saturated with cholesterol, the bile salt + phospholipid: cholesterol of 24.8 +/- 12.7 in control animals altering to 9.1 +/- 6.2 in animals receiving phenobarbital. Hepatic bilirubin uridine diphosphate-glucuronyl transferase activity was not increased in animals on phenobarbital. It was concluded that, in the hamster at least, there is no indication that large doses of phenobarbital will reduce the potential for gallstone formation. PMID- 4206461 TI - Immunogenetic aspects of nasopharyngeal carcinoma. II. Analysis of ABO, rhesus and MNSs red cell systems. PMID- 4206462 TI - Binding of metabolites of dietary 4-dimethyl-aminoazobenzene and 2-methyl-4 dimethylamino-azobenzene to rat liver DNA and protein of subcellular fractions. PMID- 4206463 TI - Prospects for the prenatal diagnosis of familial hypercholesterolemia. PMID- 4206464 TI - Low dosage anti-D immunoglobulin in the prevention of rhesus isoimmunization. PMID- 4206465 TI - Periodontal traumatism produced by sustained increase in occlusal vertical dimension: a histopathological study. PMID- 4206466 TI - Demonstration by placebo response in asthma by means of exercise testing. PMID- 4206467 TI - Isolation of human and porcine islets of Langerhans and islet transplantation in pigs. PMID- 4206468 TI - Positive Foley catheter tip cultures--fact or fancy? PMID- 4206469 TI - Editorial: Prostaglandins--tour d'horizon. PMID- 4206470 TI - Analysis of selected characteristics of a matched sample of nonprofit and proprietary nursing homes in the state of Washington. PMID- 4206471 TI - Ferulic acid as the inductor of messenger RNA synthesis related to laccase formation in the wood rotting fungus Pleurotus ostreatus. PMID- 4206472 TI - Bacterial colonial microstructure. PMID- 4206473 TI - Effect of esters of p-hydroxybenzoic acid on spheroplasts of Serratia marcescens and protoplasts of Bacillus megaterium. PMID- 4206474 TI - Evolution in action. PMID- 4206475 TI - Reduction in brain dopamine following experimental cerebral ischaemia. PMID- 4206476 TI - Blue-green bacteria synthesise L-tyrosine by the pretyrosine pathway. PMID- 4206477 TI - Vaccination of rhesus monkeys against malaria by use of sucrose density gradient fractions of Plasmodium knowlesi antigens. PMID- 4206478 TI - Vitamin B12 antagonism by monocarboxylic acids and anilides of cyanocobalamin. PMID- 4206479 TI - Human thyroxine-binding globulin (TBG) solid phase radioassay. PMID- 4206480 TI - Circulating antibodies and leucocyte migration inhibition to colon-associated antigen in ulcerative colitis and Crohn's disease. PMID- 4206481 TI - Tuberculosis in a domesticated Asiatic elephant Elephas maximus. PMID- 4206482 TI - [Experience in providing genetic counseling in a case of immunological conflict in obstetrical practice]. PMID- 4206483 TI - [The collateral communications of the retinal circulation with the choroidal circulation at the optic nerve head (author's transl)]. PMID- 4206484 TI - Miliary tuberculosis. PMID- 4206485 TI - Aspergillus species endocarditis. The new face of a not so rare disease. PMID- 4206486 TI - [Development of bacterial resistance against trimethoprim-sulfamethoxazole (Eusaprim)]. PMID- 4206487 TI - Methods to determine CO2 levels in a gonococcal transport system (Transgrow). PMID- 4206488 TI - The post-mortem microbiological analysis as an indicator of nosocomially significant microorganisms in the hospital environment. PMID- 4206489 TI - A five-year inhalation study with natural uranium dioxide (UO2) dust. II. Postexposure retention and biologic effects in the monkey, dog and rat. PMID- 4206490 TI - Childhood acromegaly: successful therapy with conventional radiation and effects of chlorpromazine on growth hormone and prolactin secretion. PMID- 4206491 TI - Transport of thyroid hormones in serum and cerebrospinal fluid. PMID- 4206492 TI - Thyrotropin and thyroidal responses to consecutive doses of thyrotropin-releasing hormone. PMID- 4206493 TI - Growth hormone, thyrotropin, and prolactin responses to thyrotropin-releasing hormone following diethylstilbestrol pretreatment. PMID- 4206494 TI - Immunogenicity and partial purification of soluble H-2 antigens extracted with hypertonic salt. PMID- 4206496 TI - Effect of anti-mu-specific immunosuppression on Friend virus leukemia. PMID- 4206495 TI - Specific binding of mouse IgE with rat mast cells. PMID- 4206497 TI - Participation of different cell populations in antigen- and mitogen-induced lymphocyte proliferation. Evidence that blastogenic factor-sensitive lymphocytes are inactivated by 5-bromo-2'-deoxyuridine. PMID- 4206498 TI - Aggregation of Fc'mu subfragments produced by tryptic hydrolysis of human IgM at elevated temperature. PMID- 4206499 TI - Forssman-containing liposomes: complement-dependent damage due to interaction with a monoclonal IgM. PMID- 4206500 TI - Skin glands as organs of communication in mammals. PMID- 4206501 TI - Comparative chemistry of sebum. PMID- 4206502 TI - Letter: Electron microscopic visualization of the folded chromosome of Escherichia coli. PMID- 4206503 TI - Letter: Crystallography of Bacillus subtilis levansucrase. PMID- 4206504 TI - Synthesis and turnover of Euglena gracilis mitochondrial DNA. PMID- 4206505 TI - Proceedings: Role of cerebellum in prism adaptation. PMID- 4206507 TI - Cerebrospinal fluid pulsatile force and focal ventricular dilatation in cases of growing skull fracture. PMID- 4206506 TI - Acid protease activity in Plasmodium falciparum and P. knowlesi and ghosts of their respective host red cells. PMID- 4206509 TI - Special needs of long-term patients. PMID- 4206508 TI - Part II. The spinal cord injured patient. PMID- 4206510 TI - [Rare blood factor Du]. PMID- 4206511 TI - Characterization of echovirus types 7, 12, and 29 hemagglutinins for human and monkey erythrocytes. PMID- 4206512 TI - The prevention of radiation-induced, early, transient incapacitation of monkeys by an antihistamine. PMID- 4206513 TI - Effects of extracellular proteases on incorporation of amino acids into protein by isolated rat tissues. PMID- 4206514 TI - Inhibition of human platelet-collagen adhesion reaction by amitriptyline and imipramine. PMID- 4206515 TI - Studies on the red cell and antibody-reactive sites of the parvovirus H-1: effect of fixatives. PMID- 4206516 TI - The role of demethylbetahistine in the depressor response to betahistine in the rat. PMID- 4206517 TI - Strain specificity of monodisperse gamma-globulin appearance after immunization of inbred mice. PMID- 4206518 TI - Paget's disease of bone. Experience with a diphosphonate (disodium etidronate) in treatment. PMID- 4206519 TI - An anatomico-physiological principle governing the direction of the gastro intestinal mucosal folds during life. PMID- 4206520 TI - Carbenicillin-induced coagulopathy. PMID- 4206522 TI - A new, highly susceptible laboratory animal for Chagas's disease. PMID- 4206521 TI - [Rifampicin in the treatment of active pulmonary tuberculosis. Controlled trial of isoniazid-rifampicin-thiocarlide versus isoniazid-streptomycin-thiocarlide in untreated tuberculosis. Treatment of relapses with the combination rifampicin ethambutol-thiocarlide]. PMID- 4206523 TI - American trypanosomiasis: a new host. PMID- 4206524 TI - Infections with Plasmodium falciparum and Plasmodium vivax in the owl monkey- model systems for basic biological and chemotherapeutic studies. PMID- 4206525 TI - The trypanocidal action of human serum and of baboon plasma. PMID- 4206526 TI - Letter: Sarcocystis in the Malaysian long-tailed monkey, Macaca irus. PMID- 4206527 TI - Letter: Malarial relapse mechanism. PMID- 4206528 TI - Sarcosporidiosis in man. PMID- 4206529 TI - Arbovirus studies in Nupeko forest, a possible natural focus of yellow fever virus in Nigeria. I. Description of the area and serological survey of humans and other vertebrate hosts. PMID- 4206530 TI - Proceedings: Attempted infection of chimpanzees and cats with Sarcocystis of cattle. PMID- 4206531 TI - Experimental Trypanosoma cruzi infection in rhesus monkeys--the acute phase. PMID- 4206532 TI - Proceedings: An infection of Klossiella muris Smith and Johnson, 1902, in a wild Mus musculus from Iran. PMID- 4206533 TI - Proceedings: Culture of Schistosoma haematobium and the effects of immune sera in vitro. PMID- 4206534 TI - Chemical and physicochemical properties of two strains of tobacco streak virus. PMID- 4206535 TI - LambdaattB-attP, a lambda derivative containing both sites involved in integrative recombination. PMID- 4206536 TI - Selective inhibition of viral protein accumulation in interferon-treated cells; nondiscriminate inhibition of the translation of added viral and cellular messenger RNAs in their extracts. PMID- 4206538 TI - Gargoylism--Hurlers syndrome. PMID- 4206537 TI - Chromatic information processing in the foveal projection (area striata) of unanesthetized primate. PMID- 4206539 TI - [Proceedings: Demonstration and quantitative determination of various antibodies in the secretion of chronic otitis]. PMID- 4206540 TI - [Proceedings: Hypoglossal nerve paralysis in patients with malignoma after high energy radiotherapy]. PMID- 4206541 TI - Effects of selective coronary hypotension and nitroglycerin or Bay a 1040 on the distribution of Rb86 clearance in the canine heart. PMID- 4206542 TI - Effects of thyrotropin-releasing hormone (TRH) in maternal, fetal and newborn rats. PMID- 4206543 TI - The effect of caloric deprivation upon thyroid function in the neonatal rat. PMID- 4206544 TI - Role of glucose as a regulator and precursor of amino acids in the pancreatic beta-cells. PMID- 4206545 TI - Aromatization by the immature rhesus monkey ovary. PMID- 4206546 TI - Cone mechanisms in the electroretinogram of the cynomolgus monkey. PMID- 4206547 TI - Experimental ocular irradiation with accelerated protons. PMID- 4206548 TI - Citrate-Mg2+ transport in Bacillus subtilis. Studies with 2-fluoro-L-erythro citrate as a substrate. PMID- 4206549 TI - Studies on human beta-D-N-acetylhexosaminidases. 3. Biochemical genetics of Tay Sachs and Sandhoff's diseases. PMID- 4206550 TI - Generation of superoxide free radical during the autoxidation of thiols. PMID- 4206551 TI - Characterization of the binding protein for epidermal growth factor. PMID- 4206552 TI - Determination of the structure and conformation of bacterial polysaccharides by carbon 13 nuclear magnetic resonance. Studies on the group-specific antigens of Neisseria meningitidis serogroups A and X. PMID- 4206553 TI - Hetero-implants of epiphyseal cartilage in fracture gaps. PMID- 4206554 TI - Immunological studies on the acidic chromogranins and on dopamine beta hydroxylase (EC 1.14.2.1) of bovine chromaffin granules. PMID- 4206555 TI - Temperature-sensitive mutations affecting the regenerative sodium channel in Drosophila melanogaster. PMID- 4206556 TI - Lactose loading test on protein calorie malnutrition. PMID- 4206557 TI - Clinical uses of central venous cannulation. PMID- 4206558 TI - Comparison of electron beams from the Siemens betatron and the Sagittaire linear accelerator. PMID- 4206559 TI - Scattered radiation dosage as a function of x-ray energy. PMID- 4206560 TI - Physical characteristics of fast-neutron beams from a compact medical cyclotron. PMID- 4206561 TI - [Editorial: Nutrition therapy in medical practice]. PMID- 4206562 TI - [Importance of the Australia antigen for the diagnosis and prevention of infectious hepatitis (a review of the literature)]. PMID- 4206563 TI - [Correlations between the neocorticalization and the structural and cellular parameters of the lateral dentate nucleus in the cerebellum of primates]. PMID- 4206564 TI - Compression osteosynthesis of lateral malleolar fractures with a figure-of-eight cerclage. PMID- 4206565 TI - Studies on Crohn's disease. 3. Concentrations of immunoglobulins G, A, and M in the mucosa of the terminal ileum. PMID- 4206566 TI - [Septicemia in the newborn infant]. PMID- 4206568 TI - Functional morphology of the lining membrane of the middle ear and Eustachian tube: an overview. PMID- 4206567 TI - Effects of methoxyflurane and two metabolites on sodium transport in the toad bladder. PMID- 4206569 TI - Mycetoma formation in Trichophyton rubrum infection. PMID- 4206570 TI - Placental lactogen levels in rhesus isoimmunization. AB - A prospective study of the plasma levels of human placental lactogen (HPL) in pregnancies complicated by rhesus isoimmunization showed that in mild and moderately affected cases the levels were normal, while in severely affected cases they were raised. Serial levels of HPL before the 26th week provide a valuable indication of fetal outcome, and we suggest that this estimation should be used routinely as an adjunct to other tests in the management of rhesus isoimmunization. PMID- 4206571 TI - Adjuvant long-term chemotherapy in complex treatment of operable breast cancer. PMID- 4206572 TI - Attempts to demonstrate "tumor-globulin" in sera of patients with malignant neoplasms. PMID- 4206573 TI - Reversible increase in pulmonary vascular permeability after Pseudomonas aeruginosa bacteremia in unanesthetized sheep. PMID- 4206574 TI - Use of an elemental diet for intestinal disorders and for the critically ill. PMID- 4206575 TI - Diverticulosis of the appendix: a collective review. PMID- 4206576 TI - Acrosomal proteinase inhibitors in rhesus monkey (Macaca mulatta) oviduct fluid. PMID- 4206577 TI - Uterine bleeding in the rhesus monkey in response to various designs of intrauterine devices. PMID- 4206578 TI - Oral contraceptive activity of danazol in the rhesus monkey. PMID- 4206579 TI - The role of mycoplasma infection in human reproductive failure. PMID- 4206580 TI - Physiological genetics of melanotic tumours in Drosophila melanogaster. VII. The relationship of dietary sterols to tumour penetrance. PMID- 4206581 TI - A case for the abolition of long stay hospitals and beds. PMID- 4206582 TI - Ejaculation by male rhesus in the absence of female partners. PMID- 4206583 TI - Glycogen synthetase and phosphorylase activities in different tissues of genetically obese mice. PMID- 4206584 TI - Pituitary function in malnutrition. PMID- 4206585 TI - Treatment of functional hypothyroidism by oral TRF monitored by daily urinary thyroxine and histamine assay. PMID- 4206586 TI - Bioassay and immunoassay measurements of serum thyrotropin in primary hypothyroidism before and after the administration of thyrotropin releasing hormone. PMID- 4206587 TI - Genetic marker systems in Arctic populations. II. Polymorphism of C'3 in Finnish Lapps. PMID- 4206588 TI - Frequency of Gm, Inv and ISf phenotypes in the population of 4 Yugoslavian villages. PMID- 4206589 TI - Carbonic anhydrase II polymorphism in Africa. PMID- 4206590 TI - ABO and Rh blood groups in relation to sex ratio of sibs. PMID- 4206591 TI - B and T lymphocyte subpopulations in human peripheral blood. PMID- 4206592 TI - Histone F1 of Tetrahymena macronuclei: unique electrophoretic properties and phosphorylation of F1 in an amitotic nucleus. AB - Histone fraction F1 has been isolated and purified from macronuclei of the ciliated protozoan, Tetrahymena pyriformis. In many respects, Tetrahymena F1 is similar to that of other organisms. It is the only Tetrahymena histone soluble in 5% perchloric acid or 5% trichloroacetic acid, has a higher molecular weight than any other Tetrahymena histone, is the histone most easily dissociated from Tetrahymena chromatin, and is susceptible to specific proteolytic cleavage. However, unlike F1 in all other organisms, Tetrahymena F1 is not the slowest migrating histone fraction when analyzed by polyacrylamide gel electrophoresis at low pH. Tetrahymena F1 also exhibits unusual behavior in sodium dodecyl sulfate containing polyacrylamide gels, migrating faster than calf thymus F1 at pH 10, and slower than calf thymus F1 at pH 7.6. Tetrahymena F1 was found to be highly phosphorylated in rapidly growing cells, suggesting that the relationship between cell replication and F1 phosphorylation previously observed in mammalian cells may extend to all eukaryotes. The observation that extensive F1 phosphorylation occurs in macronuclei, which divide amitotically, argues against a unique role for F1 phosphorylation in the process of chromosome condensation at mitosis. PMID- 4206593 TI - Nonlethal deciliation of Tetrahymena by a local anesthetic and its utility as a tool for studying cilia regeneration. PMID- 4206595 TI - Technique for obtaining pure endometrial fluid from rhesus monkeys. PMID- 4206594 TI - Genetic control of mitochondrial thymidine kinase in human-mouse and monkey-mouse somatic cell hybrids. AB - Distinctive thymidine (dT) kinase molecular forms are present in mouse, human, and monkey mitochondria. Disk polyacrylamide gel electrophoresis (disk PAGE) analyses have shown that the mitochondrial-specific dT kinases differ from cytosol dT kinases in relative electrophoretic mobilities (Rm). Furthermore, the mouse mitochondrial dT kinase differs in Rm value from primate mitochondrial dT kinases. The mouse and primate cytosol dT kinases can also be distinguished. Disk PAGE analyses have been carried out on the cytosol and mitochondrial dT kinases of human-mouse (WIL-8) and monkey-mouse (mK.CV(III)) somatic cell hybrids in order to learn whether the mitochondria of the hybrid cells contained murine mitochondrial-specific, primate mitochondrial-specific, or both dT kinases. WIL-8 cells were derived from cytosol dT kinase-negative, mitochondrial dT kinase positive mouse fibro blasts and from cytosol dT kinase-positive, mitochondrial dT kinase-positive human embryonic lung cells; they contained mostly mouse chromosomes and a few human chromosomes, including the determinant for human cytosol dT kinase. The mK.CV(III) cells were derived from cytosol dT kinase negative, mitochondrial dT kinase-positive mouse kidney cells and from cytosol dT kinase-positive, mitochondrial dT kinase-positive monkey kidney cells; they contained mostly mouse chromosomes and a few monkey chromosomes, including the determinant for monkey cytosol dT kinase. Disk PAGE analyses demonstrated that the mitochondria of human-mouse and monkey-mouse somatic cell hybrids contained the mouse-specific mitochondrial dT kinase but not the human- or monkey-specific mitochondrial dT kinase. These findings suggest that primate cytosol and mitochondrial thymidine kinase genes are coded on different chromosomes. PMID- 4206596 TI - The effect of the concentration of golden hamster spermatozoa on the acrosome reaction and egg penetration in vitro. PMID- 4206597 TI - Extracorporeal chemotherapy with L-asparaginase in man. PMID- 4206598 TI - Everting ectopic ureteroceles. PMID- 4206599 TI - Symptomatic therapy in viral illness. A controlled study of effects on work performance. PMID- 4206600 TI - Biopsy of enlarged, superficial lymph nodes. PMID- 4206601 TI - Editorial: Pancreatic transplants: new wrinkles. PMID- 4206602 TI - Antenatal diagnosis and therapeutic trends in sphingolipidoses. PMID- 4206603 TI - Minocycline (minocin). PMID- 4206604 TI - [Keto-acidosic hyperglycemic coma. Physiopathology and therapy]. PMID- 4206605 TI - Explanation of degree of correlation of sibling generation times in animal cells. PMID- 4206606 TI - Autosomal recessive mutation in sugar response of Drosophila. PMID- 4206607 TI - Retardation of discrimination reversal by delta9-tetrahydrocannabinol in monkeys. PMID- 4206608 TI - Cholinergic influence on intravenous cocaine self-administration by rhesus monkeys. PMID- 4206609 TI - Acute tolerance to the effects of delta-9-tetrahydrocannabinol on spaced responding by monkeys. PMID- 4206611 TI - [Pseudomonas aeruginosa bacteriophages. 3. Electron microscopic study of the phages]. PMID- 4206610 TI - [Submicroscopic structure of the bacterial cell wall (review of the literature)]. PMID- 4206612 TI - Parenteral hyperalimentation--a quality of care survey and review. PMID- 4206613 TI - Physiochemical considerations in intravenous hyperalimentation. PMID- 4206614 TI - Electrolyte compatibility in a synthetic amino acid hyperalimentation solution. PMID- 4206615 TI - Monitoring the effectiveness of antimicrobial agents in a general hospital. PMID- 4206616 TI - Stability of parenteral solutions of cefazolin sodium. PMID- 4206617 TI - Primary malignant medulloepithelioma of the retinal stalk. PMID- 4206618 TI - Experimental retinal detachment in the owl monkey. 10. The early receptor poential. PMID- 4206619 TI - Hyaluronidase effects on aqueous outflow resistance. Quantitative and localizing studies in the rhesus monkey eye. PMID- 4206620 TI - The effect of tobramycin on rabbit eyes. PMID- 4206621 TI - The effect of tobramycin on gentamicin-resistant strains in Pseudomonas keratitis. PMID- 4206622 TI - The zoogeography of Polychromophilus and description of a new species of a gregarine (Lankesteria galliardi). PMID- 4206623 TI - [On the possible viviparity of the sarcopt of human gale]. PMID- 4206624 TI - Letter: Prey-predator transmission in the epizootiology of ovine sarcosporidiosis. PMID- 4206625 TI - Mechanics of ciliary locomotion. PMID- 4206626 TI - Fibrous dysplastic lesions of the jaws in Nigerians. PMID- 4206627 TI - [Rate of irreversible in vivo degradation of free L-phenylalanine. Effect of somatotropic hormone]. PMID- 4206628 TI - [Predominant action of a hydroxylated derivative of progesterone on the in vitro maturation of ovocytes of the rainbow trout (Salmo gairdnerii)]. PMID- 4206629 TI - [Electron microscopy autoradiographic study of RNA synthesis sites in granulosa cells of the viviparous lizard, Lacerta vivipara Jacquin]. PMID- 4206630 TI - [Influence of lecithins on the inhibitory effect of cholesterol towards streptolysin O]. PMID- 4206631 TI - [Partial protein sequence of an Aucuba strain of the tobacco mosaic virus]. PMID- 4206632 TI - [Presence of 8S light RNA in cells chronically infected by the murine sarcoma virus (Moloney strain)]. PMID- 4206633 TI - [Presence of an irido type virus in the male cells of Nereis diversicolor (O.F. Muller)]. PMID- 4206634 TI - [Serum antibodies and local antibodies after subcutaneous or intranasal influenza vaccination]. PMID- 4206635 TI - [A new pathogenic hypothesis of mucoviscidosis: hyperactivity of microsomal glycosyl-transferases]. PMID- 4206636 TI - [Cytostatic therapy of gynecological carcinoma]. PMID- 4206637 TI - Distribution of the Kell blood groups in the Spanish population. PMID- 4206638 TI - The retinotectal projection from a double-ventral compound eye in Xenopus laevis. PMID- 4206639 TI - Germ cell migration in toad (Bufo bufo): effect of ventral grafting of embryonic dorsal regions. PMID- 4206640 TI - Detection of relationships among microsporidan isolates by electrophoretic analysis: hydrophobic extracts. PMID- 4206641 TI - Detection of relationships among microsporidan isolates by electrophoretic analysis: hydrophilic extracts. PMID- 4206642 TI - The effect of cryosurgery on peripheral nerves. PMID- 4206643 TI - An immunologic rationale for suture line recurrence in carcinoma of the colon. PMID- 4206644 TI - Intravenous hyperalimentation in cancer patients. PMID- 4206645 TI - Family structure, child location and nutritional disease in rural Haiti. PMID- 4206646 TI - Letter: Hyperosmolar diabetic coma--ketotic and nonketotic. PMID- 4206647 TI - An evaluation of the latex agglutination test for the detection of hepatitis associated antigen. PMID- 4206648 TI - Study reveals increases--in costs, in per diem rates, and in per diem expenditures. PMID- 4206649 TI - Associative learning of Drosophila melanogaster. PMID- 4206650 TI - Negative reinforcing properties of morphine-antagonists in naive rhesus monkeys. PMID- 4206651 TI - [Intravascular volume and flow resistance of the greater- and pulmonary circulations under the effect of nitroglycerin]. PMID- 4206652 TI - [Effect of antitumor preparations on the enzymes of serotonin metabolism in the liver of mice]. PMID- 4206653 TI - [A sensitive microassay for UDP-glucuronyltransferase in liver homogenates, using (14C)p-nitrophenol as substrate (author's transl)]. PMID- 4206654 TI - Homocytotropic antibody in schistosomiasis mansoni. PMID- 4206655 TI - Allergic reaction patterns in relation to age, sex, season, eosinophilia and some genetic marker systems. PMID- 4206657 TI - African swine fever: detection of antibody by reverse single radial immunodiffusion. PMID- 4206658 TI - Association of pili with rough colony type of Moraxella bovis. PMID- 4206659 TI - Scanning isoelectric focusing in small density-gradient colums. 3. A method for detailed mapping of biological activity of column contents applied to pea lipoxygenase. PMID- 4206660 TI - Affinity chromatography of carbonic anhydrase. PMID- 4206661 TI - The nose as a model for the study of respiratory tract allergic disease. PMID- 4206662 TI - Fractionation and chemical characterization studies on Micropolyspora faeni antigens. PMID- 4206663 TI - Immunology of byssinosis: a study of the reactions between the isolated byssinosis "antigen" and human immunoglobulins. PMID- 4206666 TI - Alpha crystallin subunits in the bovine lens. PMID- 4206664 TI - Characterization of reaction centers from photosynthetic bacteria. II. Amino acid composition of the reaction center protein and its subunits in Rhodopseudomonas spheroides R-26. PMID- 4206665 TI - Alpha-keto esters as substrates of erythrocyte carbonic anhydrase. Kinetic studies of enzyme-catalyzed hydration of methyl and ethyl pyruvate. PMID- 4206667 TI - Root-end closure techniques including apexification. PMID- 4206668 TI - [Septate contacts in syzygy of Gregarina Polymorpha (Protozoa)]. PMID- 4206669 TI - [N6-dimethylaminopurine in DNA of algae species]. PMID- 4206670 TI - [Inhibiting effect of ATP on the process of enzymatic degradation of deoxyribonucleoproteins]. PMID- 4206671 TI - Thyrotropin response to thyrotropin releasing hormone in normal subjects. PMID- 4206672 TI - Activity of neurons in the lower precentral cortex during voluntary and rhythmical jaw movements in the monkey. PMID- 4206673 TI - Homologues of the human M-N blood types in gorillas and other non-human primates. PMID- 4206675 TI - Diclonal and multiple gammopathies. PMID- 4206674 TI - Glycolytic intermediates and adenine nucleotides of human platelets. I. The influence of ACD and EDTA anticoagulants. PMID- 4206676 TI - Preprothrombin and prothrombin in full-term newborns. PMID- 4206678 TI - [Treatment of recurrent sprain of the ankle]. PMID- 4206677 TI - Platelet aggregation by ristocetin in EDTA plasma: extension clumping with high concentrations of EDTA. PMID- 4206679 TI - [Monoclonal gammopathy in patients with epithelial tumors]. PMID- 4206680 TI - Basilar membrane tuning curves in the guinea pig. PMID- 4206681 TI - Evidence from Mossbauer experiments for nonlinear vibration in the cochlea. PMID- 4206684 TI - The significance of post-traumatic status epilepticus in childhood. AB - Five cases of early post-traumatic status epilepticus in childhood are reported. In all cases the trauma was apparently of a minor nature and the seizures appeared within two hours after injury. In none of the cases was a significant intracranial clot detected, nor was lasting cerebral damage evident. This is in contrast with adults, where status epilepticus after head injury is thought to be an ominous sign. Rapid improvement in level of consciousness after prompt treatment is certainly the most important criterion in assessing the role of the seizures. In the same period of time, post-traumatic status epilepticus was not seen in children with more severe head injury. PMID- 4206686 TI - [Relation between dose and fractional prolonged irradiation of Ehrlich tumor with fast electrons]. PMID- 4206685 TI - Foci of degeneration produced by measles virus in cell cultures with antibody free liquid medium. PMID- 4206687 TI - [Dosimetric system of the B5M-25 type medical betatron]. PMID- 4206688 TI - [Proteins in resuscitation]. PMID- 4206689 TI - Study indicates which patients nurses don't like: the unpleasant, the long-term, the mentally ill, the hypochondriacs, and the dying. PMID- 4206690 TI - Biologic monitor is best test of ETO sterilizer. PMID- 4206691 TI - [Antibiotic prophylaxis in children with hydrocephalus and Spitz-Holter valve (author's transl)]. PMID- 4206692 TI - Membrane-to-membrane interactions in mitochondria treated with basic proteins. PMID- 4206696 TI - The relationship of a caprine mycoplasma to PG3, the type strain of Mycoplasma mycoides subsp. capri. PMID- 4206697 TI - Incidence and significance of mycoplasmas in sick cats. PMID- 4206698 TI - Influence and use of the employ of disodium cromoglycate "DSCG" on circadian rhythms in pulmonary mechanics. PMID- 4206699 TI - [Problems of infection in patients with burns]. PMID- 4206701 TI - [Structure of the somatic antigens of the plague microbe]. PMID- 4206700 TI - [Factors in bacterial pathogenicity and the problem of protective antigens]. PMID- 4206702 TI - [Modern concepts of the diphtheria exotoxin and the mechanism of its synthesis]. PMID- 4206703 TI - Reaginic antibodies and helminth infection. PMID- 4206704 TI - [Electron microscopic studies of Vero cells infected with the genetically homogeneous and heterogeneous Venezuelan equine encephalomyelitis virus]. PMID- 4206705 TI - Hydroxyproline excretion in bovine puerperal paresis with special reference to bone resorption. PMID- 4206706 TI - Clinical symptoms induced by E. coli endotoxin in goats. PMID- 4206707 TI - [Blood changes in rats fed diets deficient in tocopherol and ubiquinone. 1. Cytological and biochemical changes in the blood of vitamin E deficient rats]. PMID- 4206708 TI - [Blood changes in rats fed diets deficient in tocopherol and ubiquinone. 2. Cytological and biochemical blood components in vitamin E deficient rats after treatment with alpha-tocopherol and alpha-tocopherol-quinone]. PMID- 4206709 TI - [Blood changes in rats fed diets deficient in tocopherol and ubiquinone. 3. Cytological and biochemical blood components in normal, vitamin E deficient, and hypophysectomized rats before and after treatment with TSH]. PMID- 4206710 TI - [Blood changes in rats fed diets deficient in tocopherol and ubiquinone. 4. Blood picture and blood coagulation factor changes in vitamin E deficient rats following stress]. PMID- 4206711 TI - [Influence of a hot summer period on reproduction in milk cows]. PMID- 4206712 TI - [Changes in the bursa of Fabricius and the thymus after splenectomy in chickens]. PMID- 4206714 TI - Intraluminal diverticulum of the duodenum--cass report and review of the literature. PMID- 4206713 TI - [Absorption of D-glucose and L-leucine from isolated lamb jejunum]. PMID- 4206715 TI - Congenital hemihypertrophy with abnormalities of the aortic arch, and of the skeletal, cutaneous and ocular systems. PMID- 4206716 TI - Whole body counting using a twin-detector scanner. PMID- 4206718 TI - The possible role of the dog in the epidemiology of ovine sarcosporidiosis. PMID- 4206719 TI - Preliminary observations on the influence of proflavin, ethidium bromide and elevated temperature on the production of the antibiotic nisin by Streptococcus lactis strains. PMID- 4206720 TI - Changes occurring in proteins of bull semen plasma owing to inflammatory conditions of the efferent ducts. PMID- 4206721 TI - [The masticatory dynamics of Macaca mulatta Zimmermann]. PMID- 4206722 TI - [Acute pancreatitis (anatomo-clinical and therapeutic data on 48 cases)]. PMID- 4206723 TI - A comparison of lorazepam, diazepam and placebo in the treatment of anxiety states. PMID- 4206724 TI - Treadmill exercise-tolerance test behavior in anginal patients treated with perhexiline maleate. PMID- 4206726 TI - Clinical and microbiological evaluation of pivampicillin in the treatment of urinary tract infections. PMID- 4206725 TI - Nefopam hydrochloride for pain relief. PMID- 4206727 TI - Effect of candicidin on fungal flora of the gastrointestinal tract. PMID- 4206728 TI - Single-session, two-dose therapy with doxycycline for gonorrhea. PMID- 4206729 TI - "Combination" anti-asthmatic therapy: recent developments. PMID- 4206730 TI - Study of the serum half life of lividomycin in uraemic patients. PMID- 4206732 TI - Doxycycline in renal insufficiency. PMID- 4206731 TI - Comparative serum theophylline levels following the oral administration of elixophyllin and somophyllino-O, a new preparation of aminophylline. PMID- 4206733 TI - A pharmacologic evaluation of fluoxymesterone in normal men. PMID- 4206734 TI - [On the antibacterial effect of subinhibitory concentrations of tetracycline (author's transl)]. PMID- 4206735 TI - Relapse in chronic urinary tract infection in a child due to Salmonella brandenburg. PMID- 4206736 TI - The place of general practice. PMID- 4206737 TI - [Frequency of microbial contamination in intravenous continuous drip: infusions]. PMID- 4206738 TI - [State of the system of histamine-histaminase and histaminopexy in patients with different forms of erysipelas]. PMID- 4206739 TI - [Restoration of intestinal eubiosis in patients with chronic colitis and enterocolitis]. PMID- 4206740 TI - [Pyocin types of Pseudomonas aeruginosa isolated in Salamanca]. PMID- 4206741 TI - [Orange acridine and bacteriological diagnosis of tuberculosis. II. (Modification)]. PMID- 4206742 TI - Methods for the measurement of chloroplast volume and structure in vitro and in vivo. PMID- 4206743 TI - Acid-base indicator for the measurement of rapid changes in hydrogen ion concentration. PMID- 4206745 TI - Hydrogen ion buffers. PMID- 4206744 TI - Nitrogen fixation--assay methods and techniques. PMID- 4206746 TI - [Photogenic epilepsy with self-induced seizures]. PMID- 4206747 TI - [Quantitative bilirubin indices of the amniotic fluid in rhesus-isoimmunization at the end of pregnancy and during labor]. PMID- 4206748 TI - Visual stimulus control of intracranial self-stimulation in the squirrel monkey (Saimiri sciureus). PMID- 4206749 TI - Prefrontal lesions alter eating and hoarding behavior in rats. PMID- 4206750 TI - [Importance of 24-hour profiles of free fatty acids in evaluation of balanced juvenile diabetes]. PMID- 4206751 TI - The operational definition of human attachment. PMID- 4206752 TI - Organic factors and psychophysiology in childhood schizophrenia. PMID- 4206753 TI - [Clinical picture and radiotherapy of malignant vulvar neoplasms]. PMID- 4206754 TI - [Dose distribution in moving beam therapy using ultrahard photons. 1. Centric and eccentric monoaxial pendulum irradiation]. PMID- 4206755 TI - [Dose distribution in moving beam therapy with ultrahard photons. 2. Biaxial pendulum irradiation]. PMID- 4206756 TI - [Deep electron therapy using pendulum irradiation. VII. Dosimetry and example for application of telecentric pendulum irradiation with electrons of 5-10 MeV (shell irradiation) under changing focus-skin distance]. PMID- 4206757 TI - [Change in sorption properties and resistance of albino rat muscle tissue exposed to cytostatic agents]. PMID- 4206758 TI - [Lipid extraction from individual isolated nerve cells]. PMID- 4206759 TI - [Bacillus cereus as the cause of bovine mastitis. I. Report on the occurrence of B-cereus mastitis and on studies concerning infection of sheep and cows with the isolated strain]. PMID- 4206760 TI - Antibiotics produced by Streptomyces. IX. Heptafungin-A, a new heptaene macrolide antibiotic. PMID- 4206761 TI - Regulated biosynthesis of protease and alpha-amylase in Bacillus subtilis. PMID- 4206762 TI - Effect of DDT and sevin on soil fungi. PMID- 4206763 TI - Phenotypic derepression of enzymes of the isoleucine-valine pathway by isoleucine in Pseudomonas aeruginosa. PMID- 4206764 TI - Serological relationship between Pseudomonas aeruginosa and Enterobacteriaceae. I. Relationship of Pseudomonas aeruginosa O antigens to Salmonella, Arizona and Citrobacter. PMID- 4206765 TI - Proceedings: New outlook on the epidemiology and epizoology of listeriosis. PMID- 4206766 TI - Proceedings: Listeria monocytogenes: some biochemical and serological aspects. PMID- 4206767 TI - Proceedings: Listeriosis: its veterinary hygienic significance in Hungary. PMID- 4206768 TI - Proceedings: Present situation of human listeriosis in Hungary. PMID- 4206769 TI - Proceedings: Biological properties of virulent and avirulent Listeria monocytogenes strains. PMID- 4206771 TI - Proceedings: Ability of Listeria monocytogenes strains to attack carbohydrates and related compounds. PMID- 4206770 TI - Proceedings: Phosphatase activity of listeria. PMID- 4206772 TI - Proceedings: Listeria monocytogenes-haemolysin: lecithinase. PMID- 4206773 TI - Proceedings: Flagellation in virulent and avirulent Listeria monocytogenes strains. PMID- 4206774 TI - Proceedings: Survival versus growth of a facultative psychrotroph. PMID- 4206775 TI - Proceedings: Experience with nalidixic acid-trypaflavine agar. PMID- 4206776 TI - Proceedings: Methods to isolate Listeria monocytogenes from different materials. PMID- 4206777 TI - Proceedings: Differential media for the isolation of Listeria monocytogenes. PMID- 4206779 TI - Proceedings: Screening examination for listeriosis in pregnancy. PMID- 4206778 TI - Proceedings: Listeriosis in professionally exposed persons. PMID- 4206780 TI - Proceedings: Serological screening of pregnant women for listeriosis. PMID- 4206781 TI - Proceedings: Listeriosis in puerperal women and their infants. PMID- 4206782 TI - Proceedings: Listeriosis and gestation. PMID- 4206783 TI - Proceedings: Tetracycline treatment of pregnant women with suspected listeriosis. PMID- 4206784 TI - Proceedings: Congenital listeriosis. PMID- 4206785 TI - Proceedings: Involvement of the central nervous system in neonatal listeriosis. PMID- 4206786 TI - Proceedings: Listeric meningitis: report of a case. PMID- 4206787 TI - Proceedings: The pathogenicity of Listeria monocytogenes. PMID- 4206788 TI - Proceedings: An outbreak of listeriosis in domestic rabbits. PMID- 4206789 TI - Proceedings: Pathogenicity of Listeria monocytogenes in the rat. PMID- 4206790 TI - Proceedings: Active immunization with formol vaccine against sheep listeriosis. PMID- 4206791 TI - Proceedings: Abortion in Gray's monkey (Cercopithecus mona) associated with Listeria monocytogenes. PMID- 4206792 TI - [High-energy radiotherapy in the treatment of epitheliomas of the hypopharynx]. PMID- 4206793 TI - The major dilemma of mental retardation: shall we prevent it? (Some social implications of research in mental retardation). PMID- 4206794 TI - [Value of passive hemagglutination tests for toxoplasmosis diagnosis]. PMID- 4206795 TI - Effect of pH on Blepharisma intermedium. 2. Cytochemical changes. PMID- 4206796 TI - Immunoglobulins in aqueous humor and iris from endogenous uveitis and cataract patients. PMID- 4206797 TI - Microsurgical studies. II. Corneal endothelial healing and posterior wound closure after "through and through" suturing. PMID- 4206798 TI - Aphakic soft contact lenses. I. A clinical and bacteriological study. PMID- 4206799 TI - Comparison of methods used for solubilization of human erythrocyte membrane protein. PMID- 4206800 TI - The attachment of IgG molecules on the red cell surface. PMID- 4206801 TI - Non-specific attachment of IgG to erythrocytes. PMID- 4206803 TI - Studies on the pyocins of Pseudomonas aeruginosa: production of contractile and flexuous pyocins in Pseudomonas aeruginosa. PMID- 4206802 TI - Methyldopa-induced erythrocyte binding IgG: another model of nonspecific attachment of immunoglobulins to erythrocytes. PMID- 4206804 TI - Studies on the pyocins of Pseudomonas aeruginosa: morphology and mode of action of contractile pyocins. PMID- 4206805 TI - The inhibition of growth of Escherichia coli spheroplasts by antibacterial agents. PMID- 4206806 TI - The bioassay of rubratoxins A and B using Tetrahymena pyriformis strain W. PMID- 4206807 TI - Childhood lead poisoning: medical review. PMID- 4206809 TI - 2-Ethylpyridine derivatives with antitubercular properties. PMID- 4206808 TI - Synthesis and antibacterial properties of substituted decylbarbituric acids. PMID- 4206810 TI - Community hospitals and Medicaid. PMID- 4206811 TI - Use of Medicaid payment files for medical care research. PMID- 4206812 TI - Quality and cost control: Medicare and beyond. PMID- 4206813 TI - [Letter: Control smears in gonorrhea]. PMID- 4206814 TI - [Cholestasis lipoprotein (LP-X). Characteristics, diagnostic value and distribution in some liver diseases in children]. PMID- 4206815 TI - New treatment for acanthosis nigricans. PMID- 4206816 TI - [Suctorian infestation of the infusorian Bursaria truncatella O. F. M]. PMID- 4206817 TI - [Methods of determination of thyrotropin releasing hormone (TRH). I. Simplified method of in vitro determination]. PMID- 4206819 TI - [Nature and function of affection (discussion of Bowlby's concept)]. PMID- 4206818 TI - Antimicrobial activity of sodium copper chlorophyllin. PMID- 4206820 TI - [The effect of subgingival cervical restoration margins on the degree of inflammation of the neighboring gingiva (a clinical study)]. PMID- 4206821 TI - [Corticosteroid preparations in endodontics]. PMID- 4206822 TI - Prevalence of Neisseria meningitidis serogroups in Egypt. PMID- 4206823 TI - Results and appraisal of a nutrition survey in Malawi. PMID- 4206824 TI - Amino acid ratios in protein-energy malnutrition. PMID- 4206825 TI - Distribution, biotransformation and excretion of bupivacaine in the rat and the monkey. PMID- 4206826 TI - Acute gonorrheal proctitis. PMID- 4206828 TI - [Occurrence of "hair discs" in the skin of mammals]. PMID- 4206827 TI - Effect of oxytetracycline, doxycycline and folic acid on nitrogen balance during parenteral nutrition. PMID- 4206829 TI - 15N studies of endogenous faecal nitrogen in infants. AB - (15)N from labelled yeast protein, fed to marasmic and recovered infants, appeared in the stool shortly after administration and continued to be excreted for 100 hours. Unabsorbed dietary (15)N, which appeared with carmine-marked stools, formed only part of this excretion. Calculations of the endogenous nitrogen content of infant stool agreed closely with those of previous workers. The use of intravenously injected (15)N showed that part of the stool nitrogen was derived from this source. It was excreted as urea, ammonia, and other compounds, and totalled about 2% of the administered urea. The persistence of the (15)N in the stool suggests that it had in part been incorporated into cellular material. PMID- 4206830 TI - Unresponsiveness to thyrotropin-releasing hormone (TRH) in treated Graves' hyperthyroidism and in euthyroid Graves' disease. PMID- 4206831 TI - Thyroxine-binding-globulin (T.B.G.) deficiency and glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in the same family. PMID- 4206832 TI - Comparison of serum prolactin and thyrotropin responses to thyrotropin-releasing hormone in patients with Graves' ophthalmopathy. PMID- 4206833 TI - The inhibition of infection by cucumber mosaic virus and influenza virus by extracts from Phytolacca americana. PMID- 4206834 TI - Physico-chemical evidence for the re-classification of the caliciviruses. PMID- 4206835 TI - Serological studies with purified neuraminidase antigens of influenza B viruses. AB - Neuraminidase (N) can be extracted from virus particles of influenza B strains by treatment with trypsin, in a form which is free from the viral HA and has specific immunological activity. The N antigen of B/LEE/40 behaves differently from that of 1965-6 strains in gel diffusion and enzyme inhibition tests with animal antisera raised by infection or by artificial immunization with the homologous or heterologous strains. The frequency and titres of NI antibody detected in human sera by B/LEE antigen are different from those found with antigen from B/Eng/13/65. The latter antibody appears to contribute to the effect of serum HI antibody in protecting volunteers exposed to a deliberate intranasal challenge infection of the B/Eng/13/65 strain. PMID- 4206836 TI - Selective elimination of Enterobacteriaceae species from the digestive tract in mice and monkeys. AB - In mice and in monkeys, ;selective' elimination of Enterobacteriaceae species from the digestive tract of animals with a sensitive flora was accomplished by oral treatment with nalidixic acid (1 mg./g. body weight in mice and 0.4 mg./g. body weight in monkeys). During treatment, the concentration of enterococci (and also of Candida albicans in the monkey) remained unaltered. This indicates that the fraction of the anaerobic microflora which is responsible for the colonization resistance of the digestive tract is not affected by the treatment. An important consequence seems to be, that elimination of yeast and fungi with fungistatic drugs can be started at the same time as elimination of Enterobacteriaceae is attempted. PMID- 4206837 TI - Mechanism of depigmentation by hydroquinone. PMID- 4206838 TI - Exposure to hepatitis B virus and development of the chronic HBAg carrier state in children. PMID- 4206839 TI - Posthypoglycemic hyperglycemia in diabetic children. PMID- 4206840 TI - Meningiomas of childhood and adolescence. PMID- 4206841 TI - The Winchester syndrome: a nonlysosomal connective tissue disease. PMID- 4206842 TI - Fucosidosis: clinical, biochemical, immunologic, and genetic studies in two new cases. PMID- 4206843 TI - Therapeutic implications of electrolyte, water, and nitrogen losses during recovery from protein-calorie malnutrition. PMID- 4206844 TI - [Significance of parenteral protein feeding in extensive gastrointestinal surgery]. PMID- 4206845 TI - Models of the saccadic eye movement control system. PMID- 4206847 TI - Production of aflatoxin by cultures derived from conidia stored in the laboratory. PMID- 4206848 TI - [Megavolt radiation in radiotherapy]. PMID- 4206846 TI - [Benign concomitant paraproteinemias. Immunoclinical study]. PMID- 4206850 TI - [Dietetic treatment of severe enteropathies (author's transl)]. PMID- 4206849 TI - [Outcomes of primary plastic surgery in tumors of the eyelids]. PMID- 4206851 TI - Chemical nature of monogenean sclerites. I. Stabilization of clamp-protein by formation of dityrosine. PMID- 4206852 TI - [Inborn errors of metabolism (author's transl)]. PMID- 4206853 TI - [Effect of thyroid hormones on pituitary prolactin response during a TRH stimulation test]. PMID- 4206855 TI - Immunochemical cross-reactivity between the dissociated capsid proteins of PVY group plant viruses. PMID- 4206854 TI - [Effects of ethynil estradiol and of androgens on the parameters of thyroid function in the syndrome of male pseudohermaphroditism with testicular feminization]. PMID- 4206856 TI - [Experimental tumors of the sciatic nerve in monkeys]. PMID- 4206857 TI - [Concentration of ethionamide and prothionamide in the blood of patients with pulmonary tuberculosis]. PMID- 4206858 TI - The effect of malnutrition on the pattern of growth in the rat kidney and the renal response to acidosis. PMID- 4206859 TI - Are silicone rubber T-tubes better than latex rubber tubes in the common bile duct? A rhesus monkey model. PMID- 4206860 TI - Radical total glossectomy. PMID- 4206861 TI - Letter: CCNU in teatment of recurrent medulloblastoma. PMID- 4206862 TI - Letter: Acute pancreatitis and diabetic ketoacidosis in hypothermia. PMID- 4206863 TI - Simple and complex spike activities of the cerebellar Purkinje cell in relation to selective alternate movement in intact monkey. PMID- 4206864 TI - Studies on the control of some simple motor tasks. V. Changes in motor output following dorsal root section in squirrel monkey. PMID- 4206865 TI - What constitutes adequate medical therapy for the patient with angina pectoris? PMID- 4206866 TI - Transcriptional control in the L-arabinose operon of Escherichia coli B-r. AB - The structural genes involved in l-arabinose metabolism are regulated by the protein product of the araC gene. This protein functions as both an activator and repressor of enzyme synthesis in this gene complex. Using lambdah80dara deoxyribonucleic acid in hybridization studies, we have shown that the ara operon, including structural genes araB, araA, and araD, is transcribed in the direction araB to araD and that initiation of transcription of these genes requires an active araC gene. The half-life of this message, approximately 3 min at 30 C, is the same in the presence or absence of the araC protein in the activator state. However, an unexplained 2-min lag in decay of ara messenger ribonucleic acid that does not occur in decay of lac messenger ribonucleic acid is observed. This lag period requires activated araC protein. PMID- 4206868 TI - Clonal analysis of cell division in the Bacillus subtilis div IV-B1 minicell producing mutant. AB - Spores of the Bacillus subtilis minicell-producing mutant div IV-B1 were germinated and grown to microcolonies in chambers which facilitate continuous observation of the developing clones with a phase-contrast microscope. Time lapse photographs were taken of 46 clones, covering the period from the beginning of outgrowth until at least two rounds of cell division had been completed. Cell lineages were constructed from contour length measurements of the photographs. These data include cell lengths, division site locations, and cell numbers in clones of various ages. From these data we have determined that the probability of a minicell being produced at any division by the div IV-B1 mutant is 0.31. The location of the abnormal division site which generates the first minicell produced in the outgrowing clone appears to be random with respect to the existing cell poles. In contrast, the location of the second abnormal division site, and hence the second minicell, is not random but rather occurs preferentially in proximity to the first minicell. This clustering of abnormal events suggests that division site location is related to pole age (generations), although other influences on minicell clustering cannot be ruled out at present. PMID- 4206867 TI - Direct enzymatic repair of deoxyribonucleic acid single-strand breaks in dormant spores. AB - With the alkaline sucrose gradient centrifugation method, it was found that dormant spores of Clostridium botulinum subjected to 300 krads of gamma radiation showed a distinct decrease in deoxyribonucleic acid (DNA) fragment size, indicating induction of single-strand breaks (SSB). A two- to threefold difference in radiation resistance of spores of two strains of C. botulinum, 33A (37% survival dose [D(37)] = 110 krads) and 51B (D(37) = 47 krads), was accompanied by relatively larger DNA fragments (molecular weight 7.9 x 10(7)) obtained during extraction from the radiation-resistant strain 33A and smaller DNA fragments (molecular weight 1.8 x 10(7)) obtained under identical conditions from radiation-sensitive strain 51B. The apparent number of DNA SSB produced by 300 krads in strains 33A and 51B was 0.37 and 3.50, respectively, per 10(8) daltons of DNA. Addition of 0.02 M ethylenediaminetetraacetic acid (EDTA) to spore suspensions during irradiation doubled the apparent number of SSB in strain 33A but had no effect on strain 51B. In vivo, 0.02 M EDTA present during irradiation to 100 to 300 krads decreased survival of spores of 33A by about 30% but had little or no effect on 51B. Survival of 33A was also reduced by about 45% when the spores were irradiated while frozen in dry ice (-75 C) and, after irradiation, immediately exposed to 0.03 M EDTA for 1 h to inhibit repair in the dormant spores. These results suggest that the highly radiation-resistant strain 33A may be able to accomplish repair of SSB during irradiation or after irradiation under nonphysiological conditions, i.e., in the dormant state. This repair can be inhibited by EDTA. Sedimentation patterns show that DNA from spores of both strains 33A and 51B did not show any postirradiation repair during the first 6 h of germination, as opposed to Bacillus subtilis spores, which exhibit repair immediately after germination. These observations suggest the existence of direct repair in physiological dormant spores of strain 33A in the cryptobiotic resting state in the absence of germination. The repair seems to be similar to that of polynucleotide ligase activity shown to be operative in some vegetative cells. Apparently radiation-sensitive strains such as 51B and B. subtilis are generally poor in DNA repair enzyme activity under conditions of spore dormancy, which may account for the approximately threefold difference in radiation sensitivity or DNA fragility of different strains, or both. PMID- 4206869 TI - Amino-terminal sequence of the tryptophan synthetase alpha chain of Bacillus subtilis. AB - The sequence of the 46 NH(2)-terminal residues of the tryptophan synthetase alpha chain of Bacillus subtilis was determined and compared with the corresponding sequences of Escherichia coli, Shigella dysenteriae, Salmonella typhimurium, Aerobacter aerogenes, Serratia marcescens, and Pseudomonas putida. A deletion of six residues was found at the NH(2)-terminal end of the alpha chain of B. subtilis. PMID- 4206870 TI - Use of ultraviolet radiation to locate dipicolinic acid in Bacillus cereus spores. AB - A novel method is described that allows a direct determination of the location of a portion of the dipicolinic acid (DPA) in spores. Ultraviolet (UV) irradiation is shown to cause cross-linkage of DPA to spore proteins which have the characteristics of membrane proteins. We suggest that DPA resides in the inner forespore membrane (IFSM) and spore cytoplasm (i.e., the spore protoplast). Only that portion of the DPA in the vicinity of the IFSM appeared to form UV-induced DPA-protein adducts. PMID- 4206871 TI - Initiation of protein synthesis by folate-sufficient and folate-deficient Streptococcus faecalis R: partial purification and properties of methionyl transfer ribonucleic acid synthetase and methionyl-transfer ribonucleic acid formyltransferase. AB - The initiation of protein synthesis by Streptococcus faecalis R grown in folate free culture occurs without N-formylation or N-acylation of methionyl-tRNA(f) (Met). Methionyl-tRNA synthetase and methionyl-tRNA formyltransferase were partially purified from S. faecalis grown under normal culture conditions in the presence of folate (plus-folate); the general properties of the enzymes were determined and compared with the properties of the enzymes purified from wild type cells grown in the absence of folate (minus-folate). S. faecalis methionyl tRNA synthetase displays optimal activity at pH values between 7.2 and 7.8, requires Mg(2+), and has an apparent molecular weight of 106,000, as determined by gel filtration, and 127,000, as determined by sucrose density gradient centrifugation. The K(m) values of plus-folate methionyl-tRNA synthetase for each of the three substrates in the aminoacylation reaction (l-methionine, adenosine triphosphate, and tRNA) are nearly identical to the respective substrate Michaelis constants of minus-folate methionyl-tRNA synthetase. Furthermore, both plus- and minus-folate S. faecalis methionyl-tRNA synthetases catalyze, at equal rates, the aminoacylation of tRNA(f) (Met) and tRNA(m) (Met) isolated from either plus-folate or minus-folate cells. S. faecalis methionyl-tRNA formyltransferase displays optimal activity at pH values near 7.0, is stimulated by Mg(2+), and has an apparent molecular weight of approximately 29,900 when estimated by sucrose density gradient centrifugation. The K(m) value of plus-folate formyltransferase for plus-folate Met-tRNA(f) (Met) does not differ significantly from that of minus-folate formyltransferase for minus-folate Met-tRNA(f) (Met). Both enzymes can utilize either 10-formyltetrahydrofolate or 10 formyltetrahydropteroyltriglutamate as the formyl donor; the Michaelis constant for the monoglutamyl pteroyl coenzyme is slightly less than that of the triglutamyl pteroyl coenzyme for both transformylases. Tetrahydrofolate and uncharged tRNA(f) (Met) are competitive inhibitors of both plus- and minus-folate S. faecalis formyltransferase; folic acid, pteroic acid, aminopterin, and Met tRNA(m) (Met) are not inhibitory. These results indicate that the presence or absence of folic acid in the culture medium of S. faecalis has no apparent effect on either methionyl-tRNA synthetase or methionyl-tRNA formyltransferase, the two enzymes directly involved in the formation of formylmethionyl-tRNA(f) (Met). Therefore, the lack of N-formylation of Met-tRNA(f) (Met) in minus-folate S. faecalis is due to the absence of the formyl donor, a 10-formyl-tetrahydropteroyl derivative. Although the general properties of S. faecalis methionyl-tRNA synthetase are similar to those of other aminoacyl-tRNA synthetases, S. faecalis methionyl-tRNA formyltransferase differs from other previously described transformylases in certain kinetic parameters. PMID- 4206872 TI - Phospholipid metabolism and membrane synthesis during sporulation in Bacillus megaterium. AB - In view of previously published reports of localized membrane growth in exponentially growing Bacillus megaterium and in sporulating Bacillus cereus, an attempt was made to describe phospholipid metabolism and the topology of membrane synthesis during sporulation in B. megaterium. The cells were pulsed with radioactive glycerol or acetate at the time of septum formation, and the specific activity of the lipid fraction was measured at various times through the free spore stage. The bulk of the material labeled during septation could not be recovered in the spore. Rather, it was found that the labeled lipid fraction underwent considerable turnover during spore development. Additionally, other experiments revealed that the lipid made before the initiation of sporulation was also subject to extensive turnover. In order to minimize both the confounding effects of lipid turnover and the possible presence of lateral diffusion of labeled lipid in the membrane, autoradiography of cells pulse labeled with radioactive glycerol at the time of septation was performed; a symmetrical grain distribution resulted. Thus, despite previously published suggestions to the contrary, the current experimental techniques could not demonstrate the existence of localized membrane synthesis in B. megaterium during sporulation. PMID- 4206873 TI - Glucose transport in Brucella abortus. AB - Brucella abortus British strain 19 transported glucose with an apparent K(m) of 0.16 mM and an apparent V(max) of 250 nmol per min per mg of N. The only common glucose analogue transported was 2-deoxyglucose (2-DOG), with an apparent K(i) of 0.73 mM. Alpha- or beta-methyl glucosides and 3-O-methylglucose were not transported. Transport was linear for 70 to 90 s, depending on the concentration of substrate used. 2-Deoxyglucose was transported as the free sugar and was not further metabolized once inside the cell. There was no glucose phosphoenolpyruvate phosphotransferase system (PEP-PTS) present, and there were no inhibitors present in Brucella cell-free extract that inhibited the Escherichia coli glucose PEP-PTS. N-Ethylmaleimide (NEM) and p chloromercuribenzoate (pCMB) completely inhibited transport of glucose and 2-DOG. Glutathione, dithiothreitol, and beta-mercaptoethanol reversed the effects of pCMB but not of NEM. A pH optimum of 7.2 and a temperature optimum of 37 to 45 C were observed for both K(m) and V(max). The glucose transport system appeared to be constitutive for glucose transport in cells grown on fructose, galactose, erythritol, or glucose. The electron transfer inhibitors carbonyl cyanide, m chlorophenylhydrazone, NaN(3), 2,4-dinitrophenol, and KCN inhibited 2-DOG transport to a greater extent than did the metabolic energy inhibitors NaAsO(4), iodoacetate, KF, and 2-heptyl-4-hydroxyquinoline-N-oxide. Dicyclohexylcarbodiimide, an inhibitor of membrane-bound adenosine triphosphatases, inhibited transport by 100%. PMID- 4206874 TI - Subunit cell wall of Sulfolobus acidocaldarius. AB - The cell wall of Sulfolobus acidocaldarius has been isolated. Cells were mechanically disrupted with a French press, and the cytoplasmic membrane was removed by extracting cell-envelope fragments with Triton X-100. The Triton insoluble cell wall material retained the characteristic subunit structure when examined in the electron microscope. Isolated cell wall fragments formed in open sheets that were easily separated from cytoplasmic contamination. Chemical studies showed that the Triton-insoluble cell wall fragments consisted of lipoprotein with small amounts of carbohydrate and hexosamine. The amino acid composition indicated a highly charged hydrophobic cell surface. The presence of diaminopimelic acid with only traces of muramic acid indicates that the cell envelope does not have a rigid peptidoglycan layer. The results of chemical analyses and electron microscopy suggest a wall-membrane interaction stabilizing the cell envelope. The chemical and physical properties of this type of cell envelope would appear to form the basis for a new major division of bacteria with the definitive characteristics of a morphologically distinct subunit cell wall devoid of peptidoglycan. PMID- 4206875 TI - Exclusion of induced bacteriophage from cells of a lysogenic Bacillus megaterium committed to sporulation. AB - Spontaneous release of the temperate bacteriophage T (phiT), carried by Bacillus megaterium 899a, occurred during early growth of the host cells. Rejuvenated cells (accomplished by a 5x dilution in fresh medium) and unrejuvenated cells were induced by mitomycin C during the course of sporulation and subsequent phage phiT production measured by burst size. Induction of sequential samples of unrejuvenated cells resulted in burst sizes that fell to zero as T(0) sporulation time in the main culture was approached. This drop in burst size was not considered a sporulation event, as it also occurred during analogous stages of growth in an asporogenous mutant. Rejuvenated, induced portions of the culture of sporulating cells of B. megaterium 899a gave large burst sizes until T(+2), when the burst sizes fell to zero. The stage I asporogenous mutant, treated in a similar manner, gave lower, but still substantial, burst sizes; thus, the sharp decline in burst size of induced rejuvenated sporulating cells appeared to be a sporulation event. Sporulating cells induced at times shortly after T(1.5) formed spores in which the induced phage were trapped until germination of the spores, which formed infectious centers. This induced phage-trapping was maximal when the sporulating cultures were induced at T(2.25). Commitment to sporulation could be defined by our system as that point beyond which rejuvenated sporulating cells were unable to support the replication of the phage. This point also correlated with the increase in induced phage-trapping by spores. Two other methods gave a similar commitment time. Commitment to sporulation, in spite of added glucose or fresh complex medium, occurred at the same time. Electron micrography showed that the committed cell was still undergoing engulfment. The fate of induced phage phiT was determined at different points during growth and sporulation. Induction at times prior to T(0), which were longer than the eclipse period of the phage, resulted in a burst size of approximately 50. At times prior to T(0), shorter than the phage eclipse period, induction led to lysis with low burst sizes, approaching zero. The pattern of spontaneous phage release during growth was similar. From T(0) up to the point of commitment to sporulation, induction resulted in the blocking of spore formation without lysis. At the commitment point, induced phage were trapped and carried into spores which germinated to give infectious centers. The spontaneous derepression of phage at a time which blocked spore formation led to 7 x 10(4) infectious centers per ml and would not normally be noticed. Derepression at the time of phage entrapment was not observed to occur without induction with mitomycin C. PMID- 4206876 TI - Properties and developmental roles of the lysyl- and tryptophanyl-transfer ribonucleic acid synthetases of Bacillus subtilis: common genetic origin of the corresponding spore and vegetative enzymes. AB - The lysyl-transfer ribonucleic acid synthetase (LRS) and tryptophanyl-transfer ribonucleic acid synthetases (TRS) (l-lysine:tRNA ligase [AMP], EC 6.1.1.6; and l tryptophan:tRNA ligase [AMP], EC 6.1.1.2) have been purified 60- and 100-fold, respectively, from vegetative cells and spores of Bacillus subtilis. There are no significant differences between the corresponding spore and vegetative enzymes with respect to their elution characteristics from columns of phosphocellulose or hydroxylapatite, their molecular weight (~130,000 for LRS and ~87,000 for TRS as determined by gel filtration), their kinetic constants for substrates (in the amino acid-dependent adenosine triphosphate-pyrophosphate exchange reaction), and the kinetics of inactivation by heat and by antibody. The Mg(2+) requirement for optimal enzyme activity of the corresponding spore and vegetative enzyme differ slightly. Mutants having defective (temperature sensitive) vegetative LRS or TRS activities produce spores in which these enzymes are also defective. The mutant spores are more heat sensitive than the parental type, but contain normal levels of dipicolinic acid. They germinate normally at the restrictive temperature (43 C), but are blocked at specific developmental stages in outgrowth. No modification in temperature sensitivity phenotype occurs during outgrowth, nor is there a change in molecular weight of the two enzymes. The implication is that the LRS and TRS activities of the vegetative and spore stages are each coded (at least in part) by the same structural gene. The temperature sensitivity of mutant spores is discussed with respect to those factors which are involved in the formation of the heat-resistant state. PMID- 4206877 TI - Alloantibodies and Australia antigen after open heart surgery. AB - The development of irregular serum antibodies (alloantibodies) following massive transfusion was studied in 144 patients who had undergone cardiac valve replacement. An overall incidence of alloimmunization of 8.3% was found. Of the 15 antibodies detected nine were Rhesus anti-E and four anti-Kell. The incidence of anti-E formation in Rhesus E-negative patients was 11.4%; the corresponding figure for anti-Kell was 3.2%. The results suggest that the risk of allo immunization is directly related to the volume of blood transfused, and Rhesus E negative persons appear to be at particular risk. Australia (Au) antigen investigations were also carried out in 102 of these cases. Three patients were Au antigen positive, one of them developing acute hepatitis. In each case no Au antigen could be detected in the donor blood that was used. It is suggested that tests for alloantibodies and for the Australia antigen should become part of the routine follow-up of any patient receiving massive transfusion. PMID- 4206878 TI - Host-parasite relationship in echinococcosis. I. Parasite biomass and antibody response in three strains of inbred mice against graded doses of Echinococcus multilocularis cysts. PMID- 4206879 TI - Observations on the relapse activity of Plasmodium simiovale in the rhesus monkey. PMID- 4206880 TI - Immunofluorescent staining of plasmodial oocysts in the mosquito. PMID- 4206881 TI - Experimental infection of monkeys with Nanophyetus salmincola. PMID- 4206882 TI - Leucocytozoon grusi sp. n. (Sporozoa: Leucocytozoidae) from a sandhill crane, Grus canadensis (L.). PMID- 4206883 TI - Parasites of golden trout from California. PMID- 4206884 TI - Effect of immune rabbit IgG on the primary immune response to Trichinella spiralis in mice. PMID- 4206885 TI - Embryonic neuropathy. A hypothesis of neural chest injury as the pathogenesis of congenital malformations. PMID- 4206886 TI - Rh(D) immunization after massive transfusion of Rh(D)-positive blood. PMID- 4206887 TI - Inhibition of Pseudomonas aeruginosa by ascorbic acid acting singly and in combination with antimicrobials: in-vitro and in-vivo studies. PMID- 4206888 TI - Red blood cell velocity in nailfold capillaries of man measured by a television microscopy technique. PMID- 4206890 TI - [Role of tactile information in pointing accuracy in the split-brain monkey]. PMID- 4206889 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 19-1974. PMID- 4206891 TI - [The incidence of chronic lymphoid leukemia antigen in other malignant hematologic diseases]. PMID- 4206892 TI - Schwann cell and myelin changes caused by some toxic agents and trauma. PMID- 4206893 TI - Temporomandibular arthropathy. PMID- 4206894 TI - South American trypanosomiasis (Chagas' disease). PMID- 4206895 TI - Letter: Mycetoma. PMID- 4206897 TI - [Study of pulmonary circulation using radioactive isotopes in infants with a heart lesion]. PMID- 4206896 TI - [Characteristics of the development of experimental hypertension and the pathomorphological changes in monkeys under chronic sodium chloride load]. PMID- 4206898 TI - [Enterotoxins produced by staphylococci and Bacillus cereus]. PMID- 4206899 TI - The effects of early malnutrition in man on body composition and adipose tissue cellularity at adult age. PMID- 4206900 TI - A clinical syndrome with inborn defect in erythropoiesis, dysplastic kidneys, eye lesions, malformation of the teeth and impaired hearing. A new syndrome in a 28 year-old woman. PMID- 4206901 TI - Evaluation of primate allografts following treatment with immuosuppression and ameroid constrictors. PMID- 4206902 TI - A technique for the prevention of pneumothorax in pulmonary aspiration biopsy. PMID- 4206903 TI - Evidence for a retinohypothalamic pathway in the golden hamster. PMID- 4206904 TI - IgG, IgA, IgM, and IgD antiglobulins in juvenile rheumatoid arthritis. PMID- 4206905 TI - Identification of bacteria from blood and joint fluids of human subjects as Bacillus licheniformis. PMID- 4206906 TI - Articular and cutaneous manifestations of gonorrhoea. Review of sixteen cases. PMID- 4206907 TI - A simple graphical method for determining the inhibition constants of mixed, uncompetitive and non-competitive inhibitors. AB - A new method is described for plotting kinetic results for inhibited enzyme catalysed reactions. It provides a simple way of determining the inhibition constant, K'(i), of an uncompetitive, mixed or non-competitive inhibitor. PMID- 4206908 TI - Preparation of some immobilized linked enzyme systems and their use in the automated determination of disaccharides. AB - 1. Glucose oxidase (EC 1.1.3.4), amyloglucosidase (EC 3.2.1.3), invertase (EC 3.2.1.26) and beta-galactosidase (EC 3.2.1.23) were covalently attached via glutaraldehyde to the inside surface of nylon tube. 2. The linked enzyme system, comprising invertase immobilized within a nylon tube acting in series with glucose oxidase immobilized in a similar way, was used for the automated determination of sucrose. 3. The linked enzyme system, comprising beta galactosidase immobilized within a nylon tube acting in series with glucose oxidase immobilized in a similar way, was used for the automated determination of lactose. 4. The linked enzyme system, comprising amyloglucosidase immobilized within a nylon tube acting in series with glucose oxidase immobilized in a similar way, was used for the automated determination of maltose. 5. Mixtures of glucose oxidase and amyloglucosidase were immobilized within the same piece of nylon tube and used for the automated determination of maltose. 6. Mixtures of glucose oxidase and invertase were immobilized within the same piece of nylon tube and used for the automated determination of sucrose. PMID- 4206909 TI - Distribution of sulphate and iduronic acid residues in heparin and heparan sulphate. AB - 1. A method was developed for determination of the uronic acid composition of heparin-like glycosaminoglycans. Polymers or oligosaccharides are degraded to monosaccharides by a combination of acid hydrolysis and deamination with HNO(2). The resulting uronic acid monosaccharides (accounting for about 70% of the uronic acid contents of the starting materials) are isolated and converted into the corresponding aldono-1,4-lactones, which are separated by g.l.c. The calculated ratios of glucuronic acid/iduronic acid are reproducible within 5%. 2. Samples of heparin from pig intestinal mucosa (molar ratio of sulphate/disaccharide unit, 2.40) and heparan sulphate from human aorta (sulphate/disaccharide ratio, 0.46) were subjected to uronic acid analysis. l-Iduronic acid constituted 77% and 19% respectively of the total uronic acid contents. 3. The correlation between the contents of sulphate and iduronic acid indicated by this finding also applied to the fractionated deamination products of the two polymers. The sulphated fragments varied in size from disaccharide to octasaccharide (or larger) and showed sulphate/disaccharide molar ratios in the range of 0.05-2.0. The proportion of iduronic acid increased with increasing ester sulphate contents of the oligosaccharides. 4. Previous studies on the biosynthesis of heparin in a cell-free system have shown that l-iduronic acid residues are formed by C-5 epimerization of d-glucuronic acid units at the polymer level; the process requires concomitant sulphation of the polymer. The results obtained in the present structural study conform to these findings, and suggest further that similar mechanisms may operate in the biosynthesis of heparan sulphate. The epimerization reaction appears to be linked to the sulphation of hydroxyl groups but does not seem to require sulphation of the target uronic acid residues. The significance of sulphamino groups in relation to the formation of iduronic acid is unknown. PMID- 4206910 TI - Inhibition of enzymes by metal ion-chelating reagents. Theory and new graphical methods of study. AB - 1. The mechanism of inhibition of enzymes by metal ion-chelating reagents is discussed and equations derived. 2. Two distinct mechanisms are postulated and graphical methods are given for differentiating between them. 3. Where the metal ion is actually removed from the enzyme to form a co-ordination complex in solution, a procedure is described for obtaining the stability constant for metal enzyme interaction, the number of metal ions involved and the stoicheiometry of metal ion-ligand interaction. PMID- 4206911 TI - Inhibition of enzymes by metal ion-chelating reagents. The action of copper chelating reagents on diamine oxidase. AB - 1. The inhibition of diamine oxidase has been studied by using the following copper-chelating reagents: 1,10-phenanthroline; 2,2'-bipyridyl; 8 hydroxyquinoline (oxine); diethyldithiocarbamate and dithio-oxamide (rubeanic acid). 2. Addition of chelating reagent caused a rapid inhibition of enzyme to a degree dependent solely on the final inhibitor concentration. Addition of substrate gave linear initial rates of reaction showing that under these conditions the inhibition was not being rapidly reversed. 3. The inhibition has been investigated by using new graphical methods and has been found in all cases to involve the chelating agents completely removing two Cu(2+) ions from the enzyme. An alternative possibility, involving ligand substitution, was eliminated. 4. A value of K=8.0x10(-33)m(-2) has been found for the enzyme in equilibrium with 2 Cu(2+) ions (i.e. beta(2), the stability constant for diamine oxidase/two Cu(2+), is 32.1). PMID- 4206912 TI - The molecular weight of J chains derived from human immunoglobulin M. AB - J chain was isolated from sulphonated human immunoglobulin M molecules by electrophoresis on polyacrylamide gels. When determined by electrophoresis in sodium dodecyl sulphate-polyacrylamide gels, the molecular weight of the protein was about 27000. After suspension in 5m-guanidine hydrochloride solution for 21 days, two groups of three bands appeared on the gels. Most of the protein dissociated to components of molecular weight 15000. The molecular weight of purified J chain was also determined by ultracentrifugation. In borate-saline solution the average weight-average molecular weight was about 29000. The molecular weight slowly decreased upon prolonged exposure to guanidine hydrochloride, and after 14 days the minimum molecular weight was about 15000. Some association between chains still existed. These data suggest that J chain derived from the paraprotein exists in borate-saline solution as dimers held by strong non-covalent forces. PMID- 4206913 TI - The incorporation of J chain into reassembled human immunoglobulin M. AB - Human IgM (immunoglobulin M) was reduced with 24mm-mercaptoethylamine. This atreatment resulted in complete dissociation to IgMs subunits and free J chain. Intr-subunit interchain disulphide bonds remained intact. The mixture then was encouraged to reoxidize. The schlieren pattern of the reoxidized mixture showed the presence of a considerable quantity of IgM in addition to residual IgMs. The isolated reassembled IgM did not dissociate in 5m-guanidinium hydrochloride. It apparently contained the same amount of covalently attached J chain as did native IgM. The J chain was a part of the high-molecular-weight Fc fragment obtained from the reassembled IgM. PMID- 4206914 TI - A new case of mu heavy chain disease: clinical and immunochemical studies. PMID- 4206915 TI - Granulocyte transfusions in leukopenic dogs: in vivo and in vitro function of granulocytes obtained by continuous-flow filtration leukopheresis. PMID- 4206916 TI - Placental transfer of 14C labelled succinylcholine in near-term Macaca mulatta monkeys. PMID- 4206917 TI - Vestibular nucleus units in alert monkeys are also influenced by moving visual fields. PMID- 4206918 TI - Immunohistochemical localization and immunoelectrophoresis of cholinergic synaptic vesicle protein constituents from the Torpedo. PMID- 4206920 TI - Digital rectal examination. PMID- 4206921 TI - Malignant melanoma: to biopsy or not to biopsy. PMID- 4206919 TI - Neocortical and limbic lesion effects on primate phonation. PMID- 4206922 TI - Classics in oncology. Sir Percivall Pott (1714-1788). PMID- 4206924 TI - Lung cancer. PMID- 4206923 TI - Diagnostic radiology for cancer. PMID- 4206925 TI - [Chemoprophylaxis of traumatic epilepsy in children]. PMID- 4206926 TI - Serum gold levels during chrysotherapy with relation to urinary and fecal excretion. PMID- 4206927 TI - Evaluation of albutoin as an antiepileptic drug. PMID- 4206928 TI - Trypanosoma cruzi: protection of mice with epimastigote antigens from immunologically different parasite strains. PMID- 4206929 TI - Influence of methods of preparation on the infectivity, agglutination, activity, and ultrastructure of bloodstream trypanosomes. PMID- 4206930 TI - Schistosoma mansoni: IgG and IgE skin-sensitizing antibodies in infected baboons. PMID- 4206931 TI - Echinococcus granulosus: penetration of macromolecules and their localization on the parasite membranes of cysts. PMID- 4206932 TI - Effects of orally administered insecticides and polychlorinated biphenyls on the parasite fauna of two species of piscivorous birds. PMID- 4206933 TI - Plasmodium cynomolgi: influence of x-irradiation and sporozoite dilution on relapse patterns in infected rhesus monkeys. PMID- 4206934 TI - Trypanosoma cruzi: possible stimulatory factor(s) on brown adipose tissue of mice. PMID- 4206936 TI - Schistosoma mansoni: effect of some cations on the proteolytic enzymes of cercariae. PMID- 4206935 TI - Heligmosomoides polygrus (equals nematospiroides dubius): humoral and intestinal immunologic responses to infection in mice. PMID- 4206937 TI - Complement fixation tests with cell culture fluid as antigen in comparison with cell culture neutralization tests in the identification of freshly isolated dengue virus: a pilot study. PMID- 4206938 TI - A study of urethritis in males with particular reference to mycoplasma and TRIC agent. PMID- 4206940 TI - Perinatal mortality and birthweight in Makassar, Indonesia. PMID- 4206939 TI - Solubilization of brain membrane proteins, polypeptide composition of fractions with different solubility characteristics. PMID- 4206942 TI - Abortive infection of lysogenic Bacillus subtilis 168(SPO2) by bacteriophage phi 1. AB - Virulent bacteriophage phi1 was not able to productively infect strains of Bacillus subtilis which were lysogenic for the temperate bacteriophage SPO2, although it adsorbed to, penetrated, and killed these bacteria. Studies of phage and host nucleic acid production in the nonpermissive host demonstrated that normal phi1 transcription was initiated early in the latent period, but this was followed by a general failure of host and phage nucleic acid synthesis about 10 to 15 min after infection. Mixed infections of phi1 and SPO2c(1), a clear-plaque mutant of SPO2, indicated that a similar inhibition of phi1 development occurred when this phage infected nonlysogenic B. subtilis cells committed to the SPO2c(1) lytic cycle. It is proposed that the SPO2- and SPO2c(1)-mediated interference did not act directly on the phi1 genome, but rather these phages altered the host physiology in such a manner that some normal step in phi1 development triggered a collapse of vital metabolic activities. PMID- 4206943 TI - Bacteriophage interference in Bacillus subtilis 168. AB - Strains of Bacillus subtilis lysogenic for temperate bacteriophage SPO2 inhibit the development of bacteriophage phi1. After infection by bacteriophage phi1, DNA and RNA synthesis in the lysogenic host terminates, culminating in cell death. Bacteriophage SPO2 also prevents the production of bacteriophage phi105. Mechanisms for these two types of bacteriophage interference are discussed. PMID- 4206941 TI - Early biochemical events occurring after infection of Bacillus cereus 569-SP1 with bacteriophage GSW. AB - After infection of Bacillus cereus 569-SP1 with the 5-hydroxymethyluracil containing phage GSW, new dTTPase, dUTPase, and dUMP-hydroxymethylase activities appear. No significant changes in activities of other pyrimidine ribonucleoside or 2'-deoxyribonucleoside triphosphate nucleotidohydrolases were detected. dUTP and dUMP inhibit the dTTPase activity, whereas dTTP failed to inhibit dUTPase activity. The K(m) value for the substrate dUTP is 10(-4) M and for dTTP is 4.85 x 10(-4) M. Thymidylate synthetase activity is inhibited only when cells are infected during the late lag or very early log phases of growth; when cells are infected with phage during mid-log, thymidylate synthetase activity is unaffected. The data support the suggestion that, although phage GSW may inhibit an otherwise expected increase in activity of thymidylate synthetase, it fails to affect the already existing activity. The data presented do not allow discrimination as to whether the phage specifies inhibition of de novo synthesis of thymidylate synthetase or the increase in activity of already existing but not fully expressed enzyme. PMID- 4206945 TI - Why residency programs in the military: the impact of history and influencing forces. PMID- 4206944 TI - Letter: Current management of gonorrhea. PMID- 4206946 TI - Acute mesenteric lymphadenitis due to Salmonella enteritidis mimicking appendicitis: case report. PMID- 4206947 TI - A review of 168 maxillo-facial fractures treated at Naval Hospital, Long Beach. PMID- 4206948 TI - Case for diagnosis. PMID- 4206949 TI - The outcome of 89 American and 224 Vietnamese sustaining brain wounds in Vietnam. PMID- 4206950 TI - Immunological basis for the development of vaccines. PMID- 4206951 TI - Ventricular septal defects caused by stab wounds: report of two cases. PMID- 4206952 TI - Hyperemia and strokes: an evaluation of radioisotope findings. PMID- 4206953 TI - Simultaneous bilateral spontaneous pneumothorax. PMID- 4206954 TI - Blood preservation solutions. XI. Raising the pH to improve hemoglobin function. PMID- 4206955 TI - Significant research and future needs for improving patient care. PMID- 4206956 TI - Complications of arterial puncture. PMID- 4206957 TI - Distribution and prevalence of Bancroftian filariasis in US Army Special Forces Camps in the Republic of Vietnam. PMID- 4206959 TI - Military medicine and everybody's medicine. PMID- 4206958 TI - Sickle crisis precipitated by exercise rhabdomyolysis in a patient with sickle cell trait: case report. PMID- 4206960 TI - Editorial: Medicine at the crossroads. PMID- 4206962 TI - [Travel fever after the Orient]. PMID- 4206961 TI - Introduction: Immunotherapy of cancer in man, a reality. PMID- 4206963 TI - Transfer of steroidal hormones from blood to the cerebrospinal fluid in the Rhesus monkey. PMID- 4206964 TI - The effect of monoamine precursors on the release of growth hormone in the Rhesus monkey. PMID- 4206965 TI - Contact between the mastitis laboratory and herd. PMID- 4206966 TI - Proctological admissions under a general surgeon. PMID- 4206967 TI - Radiological diagnosis. PMID- 4206968 TI - Management of bowel complications of radiotherapy. PMID- 4206969 TI - Effects of long-term anticonvulsant therapy on calcium and vitamin D metabolism. PMID- 4206970 TI - [Determination of carbaryl in milk]. PMID- 4206971 TI - [Childhood epilepsy: current concepts of prognosis and treatment]. PMID- 4206972 TI - [Hemodynamics and metabolic effects of a slow-release preparation of Mitroglycerin]. PMID- 4206973 TI - A study of the microbiological environment of the respiratory intensive care unit, the Royal Victoria Hospital. PMID- 4206974 TI - The adsorption of Pseudomonas aeruginosa pilus-dependent bacteriophages to a host mutant with nonretractile pili. PMID- 4206975 TI - A spheroplast assay for recombination in bacteriophage lambda DNA. PMID- 4206977 TI - Trauma rounds: The role of hyperalimentation in patients with multiple injuries. PMID- 4206976 TI - Purification and properties of Herpesvirus saimiri DNA. PMID- 4206978 TI - [Deaths caused by chronic pyelonephritis and Kimmelstiel-Wilson syndrome among diabetics]. PMID- 4206979 TI - [Effects of ethanol on kidneys]. PMID- 4206980 TI - [Tissue histocompatibility antigens and typing of organ donors in transplantation]. PMID- 4206981 TI - [Treatment of middle lobe syndrome]. PMID- 4206982 TI - [Case of nephrogenic polycythemia]. PMID- 4206983 TI - [Case of penetrating heart injury treated surgically]. PMID- 4206984 TI - [Duodenal content reflux into bile ducts following choledochoduodenostomy]. PMID- 4206985 TI - [Inflammation of appendix stump following appendectomy]. PMID- 4206986 TI - [Recurrent ileus due to developmental intestine anomaly]. PMID- 4206988 TI - [Use of furosemide in treatment of acute renal failure in the course of glomerulonephritis in children]. PMID- 4206987 TI - [Case of foreign body cystouterine recess in a 10-year-old girl]. PMID- 4206989 TI - [Treatment of nephrotic syndromes with cynarine]. PMID- 4206990 TI - [Carbochromen in treatment of coronary arterial disease]. PMID- 4206991 TI - [Pannodine in treatment of selected acute infections in children]. PMID- 4206992 TI - [Linkocin in treatment of puerperal mastitis]. PMID- 4206994 TI - [Enclematic questions asked by patients]. PMID- 4206993 TI - [Meteorotropic diseases diagnosed according to new criteria of weather conditions]. PMID- 4206995 TI - Stage 3 Hodgkin's disease: six years experience. PMID- 4206996 TI - Whole cell heat-killed gram-negative bacilli vaccine. PMID- 4206997 TI - C. G. Kratzenstein professor physices experimentalis Petropol. et Havn. and his Studies on Electricity during the eighteenth century. PMID- 4206998 TI - [Reflex algodystrophy and fractures of the hand]. PMID- 4206999 TI - Carcinoma linguae. A series of 96 patients. PMID- 4207000 TI - The distribution of 198Au injected intravenously as a colloid and in solution. PMID- 4207001 TI - Spectral distributions from 60Co therapy units. PMID- 4207003 TI - Cervical pharyngostomy. A safe alternative for gastrointestinal decompression. PMID- 4207002 TI - Measurements of primary spectra from a kilocurie 60Co unit and a 6 MeV linear accelerator. PMID- 4207004 TI - Eschar: a major factor in postburn pneumonia. PMID- 4207005 TI - High velocity missile injury. An experimental study of the retentive forces of tissue. PMID- 4207006 TI - Use of chemically defined diets in the management of patients with acute inflammatory bowel disease. PMID- 4207007 TI - Surgical intervention in acute necrotizing pancreatitis. PMID- 4207008 TI - Review of the toxicity of long-term phosgene exposure. PMID- 4207009 TI - Preparation of hair for lead analysis. PMID- 4207010 TI - Recurrent experimental allergic polyganglioradiculoneuritis. Multiple demyelinating episodes in rhesus monkey sensitized with rabbit sciatic nerve myelin. PMID- 4207012 TI - Penetrating keratoplasty with use of through-and-through nylon sutures. PMID- 4207011 TI - Early traumatic epilepsy. Incidence and significance after nonmissile injuries. PMID- 4207013 TI - Xenon photocoagulation and the retinal vasculature. PMID- 4207015 TI - Effects of alpha-ecdysone, beta-ecdysone and inokosterone on the in vitro evagination of Drosophila leg discs and the subsequent differentiation of imaginal integumentary structures. PMID- 4207014 TI - Treatment of nonspecific diarrhea in infants. PMID- 4207016 TI - Developmental changes of adenosine deaminase, xanthine oxidase, and uricase in mouse tissues. PMID- 4207017 TI - Environmental regulation of enzymes in the microbodies and mitochondria of dark grown, greening, and light-grown Euglena graclis. PMID- 4207018 TI - Platelet and fibrinogen reactions in Pseudomonas aeruginosa exotoxin shock. PMID- 4207019 TI - Brachial arteriovenous shunts for hemodialysis and extracorporeal procedures. PMID- 4207020 TI - Influence of age and sex on serum copper and ceruloplasmin levels. PMID- 4207022 TI - Gold kinetics following aurothiomalate therapy: use of a whole-body radiation counter. PMID- 4207021 TI - A predictor for total body potassium in man based on height, weight, sex and age: applications in metabolic disorders. PMID- 4207024 TI - [Endoscopic diagnosis of duodenal diverticulosis]. PMID- 4207023 TI - [Anomalies of the gallbladder and their roentgenodiagnosis]. PMID- 4207026 TI - Transfusion of neutrophils as prevention or treatment of infection in patients with neutropenia. PMID- 4207025 TI - Calcitonin as a tumor marker. Use of the radioimmunoassay for calcitonin in the postoperative evaluation of patients with medullary thyroid carcinoma. PMID- 4207028 TI - Effect of ascorbic acid on lipoprotein lipase activity. PMID- 4207029 TI - Cortical control of cell division. PMID- 4207027 TI - [Research on work capability of traumatic epileptics (author's transl)]. PMID- 4207030 TI - [Histamine metabolism in periodic disease]. PMID- 4207031 TI - [Hydantoin-induced lymphadenopathy]. PMID- 4207033 TI - [Oral depot preparations. 5. Nitro compounds]. PMID- 4207032 TI - Effect of FSH on the in vitro uptake of 3H-testosterone by the cultured seminiferous tubule. PMID- 4207034 TI - [Radioimmunologic method for the detection of Australia antigen]. PMID- 4207035 TI - [Effect of ABO and Rh blood group factors on the frequency, nature of the course and outcome of certain infectious diseases]. PMID- 4207036 TI - [Use of a universal antirhesus serum in therapeutic and prophylactic institutions]. PMID- 4207037 TI - [Morquio-Ullrich syndrome]. PMID- 4207038 TI - Maturation of fetal body systems. Report of a WHO scientific group. PMID- 4207039 TI - Mycoplasma aetiology of keratoconjunctivitis ("pink-eye") in domestic ruminants. PMID- 4207040 TI - The role of the conceptus in plasma protein metabolism in the rat. PMID- 4207041 TI - The effect of corticosteroid on absorption and endogenous production of immunoglobulins in calves. PMID- 4207043 TI - Proceedings: A technique for studying drug absorption from the lung in man. PMID- 4207042 TI - Proceedings: The influence of glucagon on regional blood flow in the rhesus monkey. PMID- 4207044 TI - Proceedings: Anti-nociceptive effects in N-substituted cyclohexylmethylbenzamides. PMID- 4207045 TI - Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase. AB - 1. DL-C-Allyglycine, 4-deoxypyridoxine hydrochloride and 3-mercaptopropionic acid have been studied with reference to their convulsant effects in mice and in baboons (Papio papio) with photosensitive epilepsy, and their action on the cerebral enzyme synthesizing gamma-aminobutyric acid (L-glutamate-1-carboxy lyase).2. In mice, the ED(50) values for seizures following intraperitoneal injection were allylglycine 1.0 mmol/kg body weight, 4-deoxypyridoxine 1.1 mmol/kg and 3-mercaptopropionic acid 0.27 mmol/kg. Latency to seizure onset was longest after allylglycine (44-240 min), intermediate after 4-deoxypyridoxine (9 114 min) and shortest after 3-mercaptopropionic acid (2.5-8 min).3. In Papio papio intravenous administration of subconvulsant doses of allylglycine (0.87-3.1 mmol/kg), or of 4-deoxypyridoxine (0.21-0.53 mmol/kg) enhanced the occurrence and persistence of myoclonic responses to intermittent photic stimulation, and augmented the associated electroencephalographic abnormalities, without modifying their character or distribution. Higher doses produced brief seizures recurring at regular intervals, between 2-14 h after allylglycine (4.0-4.3 mmol/kg) or 1-4 h after 4-deoxypyridoxine (0.53-0.87 mmol/kg). Electroencephalographically these seizures originated unilaterally in the occipital or posterior parietal cortex.4. In Papio papio photically-induced epileptic responses were enhanced 5-10 min after the intravenous injection of 3-mercaptopropionic acid (0.09-0.28 mmol/kg). A sequence of brief generalized seizures followed by complete recovery occurred 4 17 min after the injection of 3-mercaptopropionic acid (0.28-0.38 mmol/kg). Fatal status epilepticus followed the injection of 3-mercaptopropionic acid (0.57-0.75 mmol/kg). E.E.G. records showed generalized cortical involvement at the onset of the seizures.5. L-Glutamate 1-carboxy-lyase (GAD) activity was determined in whole brain homogenates from mice killed at various intervals after receiving i.p. a convulsant dose of one of the compounds. Inhibition of GAD activity was evident 30-60 min before seizure onset following allylglycine or 4 deoxypyridoxine administration, and was maximal (40-60%) just before or during seizure activity. Addition of pyridoxal phosphate to the brain homogenate relieved inhibition produced by 4-deoxypyridoxine but not that produced by allylglycine. Inhibition of GAD activity in brain homogenates from animals killed 2 or 4 min after injection of a convulsant dose of 3-mercaptopropionic acid varied from 0-49% depending on the dose of 3-mercaptopropionic acid and the concentration of substrate in the assay system.6. Kinetic analysis of the inhibition of GAD activity following direct addition of the compounds to mouse brain homogenates indicated that 3-mercaptopropionic acid (0.01-0.5 mM) was competitive with respect to the substrate. A comparable percentage inhibition of GAD activity was obtained only with much higher concentrations of 4 deoxypyridoxne, i.e. 10-50 mM. Allylglycine in vitro was a very weak inhibitor of GAD activity.7. Three biochemically different mechanisms underlie the inhibition of cerebral GAD activity that precedes seizures induced by ailylglycine, 4 deoxypyridoxine and 3-mercaptopropionic acid. The data are consistent with a critical reduction in the rate of synthesis of gamma-aminobutyric acid being responsible for the onset of seizures. PMID- 4207046 TI - Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. AB - 1. Resting splenic venous outflow from anaesthetized dogs contains prostaglandin like material: the concentration increases after intra-arterial injections of bradykinin into the spleen, and is abolished by treatment with indomethacin.2. Intra-arterial injections of bradykinin into the spleen of lightly anaesthetized dogs elicit a dose-dependent reflex increase in the blood pressure, which is reduced but not abolished by treatment with indomethacin.3. Addition of prostaglandin E(1) or E(2) either by injections or by infusions restores the reflex increase in the blood pressure due to bradykinin injections after indomethacin treatment.4. The sensitizing action of endogenously released prostaglandins at or near the afferent nerve endings is discussed.5. The analgesic activity of aspirin-like drugs is explained in terms of the removal of the sensitizing activity of prostaglandins. PMID- 4207047 TI - Ganglioside changes in slow virus diseases: analyses of chimpanzee brains infected with kuru and Creutzfeldt-Jakob agents. PMID- 4207048 TI - Short latency jaw movement produced by low intensity intracortical microstimulation of the precentral face area in monkeys. PMID- 4207049 TI - The permeability to small ions of tight junctions between cerebral endothelial cells. PMID- 4207050 TI - Behavioral consequences of selective subtotal ablations in the postcentral gyrus of Macaca mulatta. PMID- 4207051 TI - Inhibition of lordosis behavior in ovariectomized guinea pigs by mesencephalic implants of progesterone. PMID- 4207053 TI - [Carbaminoyl choline in the treatment of chronic open-angle glaucoma. Comparison with pilocarpin]. PMID- 4207052 TI - [Type 2 mucolipidosis, or inclusion cell disease. Apropos of 3 cases with corneal lesions]. PMID- 4207054 TI - The growth of Mycobacterium leprae in snakes. PMID- 4207055 TI - Cell electrophoresis of amphibian blastula and gastrula cells; the relationship of surface charge and morphogenetic movement. PMID- 4207056 TI - DNA synthesis following gross alterations of the nucleocytoplasmic ratio in the ciliate Stentor coeruleus. PMID- 4207057 TI - [The secondary disease in hematology and induced by antineoplastic chemotherapy]. PMID- 4207059 TI - Further studies with lipoamide dehydrogenase mutants of Escherichia coli K12. PMID- 4207058 TI - Radiation resistance of spores of Bacillus subtilis and B. stearothermophilus at various water activities. PMID- 4207061 TI - The spontaneous release of somatic antigen from Vibrio cholerae. PMID- 4207060 TI - In vitro protein synthesis and measurement of the stability of messenger RNA in the blue-green alga, anabaena variabilis. PMID- 4207062 TI - The mast cells of the mammalian central nervous system. 2. The effect of proton irradiation in the monkey. PMID- 4207063 TI - [Present-day views on the mechanism of action and possible clinical use of adrenergic drugs in ophthalmology]. PMID- 4207064 TI - [Viruses in ocular pathology. V. Laboratory studies]. PMID- 4207065 TI - [Medical diagnosis in hospitalized physically ill chronic patients in a county district]. PMID- 4207066 TI - [Relation between disease picture and need of health care. Dimension analysis in the development of methods for medical care estimation]. PMID- 4207067 TI - [3 cases of incontinentia pigmenti. Clinical, histological and ultrastructural study]. PMID- 4207068 TI - [Letter: Fat embolism prevention during prolonged parenteral nutrition: choice of lipid emulsion]. PMID- 4207069 TI - Some paediatric problems of Australian Aborigines. PMID- 4207071 TI - Conditioned behavior in Drosophila melanogaster. AB - Populations of Drosophila were trained by alternately exposing them to two odorants, one coupled with electric shock. On testing, the flies avoided the shock-associated odor. Pseudoconditioning, excitatory states, odor preference, sensitization, habituation, and subjective bias have been eliminated as explanations. The selective avoidance can be extinguished by retraining. All flies in the population have equal probability of expressing this behavior. Memory persists for 24 hr. Another paradigm has been developed in which flies learn to discriminate between light sources of different color. PMID- 4207070 TI - Mechanism of IgM polymerization. AB - The stoichiometry of J chain in pentamer IgM has been determined by measuring the radiolabeled thiols in the constituent chains after complete reduction and alkylation of the polymer. One mole of J was found to be disulfide bonded to 1 mol of pentamer. The linkage of J chain in IgM has been determined by correlating the J disulfides cleaved with the subunits released after limited reduction and alkylation of the polymer. The analyses showed that: (a) Significant amounts of monomers, as well as small quantities of dimers, trimers, and tetramers, were generated by the reducing conditions employed. (b) The number of J disulfide bonds broken did not correspond to the extent of depolymerization. (c) No J disulfides were cleaved in the J-containing dimer products of the limited reduction. These data demonstrated that the J chain is located as a disulfide clasp between two of the IgM monomer subunits. From the observed linkage, the assembly of IgM is postulated to proceed by a series of sequential disulfide exchanges beginning with the formation of the J-containing dimer. PMID- 4207072 TI - Control of translation in cultured cells: continued synthesis and accumulation of messenger RNA in nondividing cultures. AB - Nontransformed animal fibroblasts in tissue culture regulate total protein and ribosomal RNA synthesis coordinately with changes in the cellular growth state. Here it is shown that the amounts and rates of synthesis of cytoplasmic poly(A) containing RNA, presumed to be mRNA, do not appreciably change with alterations in growth state. In nongrowing (resting) cultures of BALB/c 3T3 cells presumptive mRNA molecules predominantly accumulate as cytoplasmic ribonucleoprotein particles; the RNA from which can be chased into the polyribosomal structure upon activation of the resting cultures with animal sera. It is suggested that the decreased protein synthetic rate in resting as compared with growing cells is in part due to a failure of preexisting mRNAs to attach to ribosomes and that addition of serum to the tissue culture medium can partially overcome this translational lesion. PMID- 4207074 TI - Prostaglandin F in moneky uterine fluid during the menstrual cycle and following steroid treatment. PMID- 4207075 TI - [Radiotherapy of bronchial carcinoma (author's transl)]. PMID- 4207073 TI - Induction of nucleolar and mitochondrial DNA replication in Tetrahymena pyriformis. AB - Selective induction of replication of nucleolar and mitochondrial DNA has been demonstrated in starved-refed cultures of Tetrahymena pyriformis by different techniques. Labeling of starved cells with [(3)H]thymidine during a nutritional shift-up and analysis of the DNA in isopycnic CsCl gradients shows that the two initially labeled species of DNA are two species banding on the heavy and light side of the bulk macronuclear DNA. In isolated macronuclei the radioactivity is found only in the high density fraction, which has been shown to be of nucleolar origin. In sucrose gradients the newly replicated mitochondrial and nucleolar DNAs sediment considerably slower than the bulk DNA, as one discrete band corresponding to a molecular weight of about 3 to 4 x 10(7). Electron microscope autoradiography of cells labeled with [(3)H]thymidine as above shows that the peripheral nucleoli of the macronucleus as well as the mitochondria are labeled before any radioactivity is found in the chromatin granules of the macronucleus. The results clearly indicate that nucleolar and mitochondrial DNA replication are under a control independent of that for the replication of bulk DNA. PMID- 4207076 TI - The family practitioner and the juvenile diabetic. PMID- 4207077 TI - The rationale for the use of drugs in the treatment of diabetes mellitus. PMID- 4207080 TI - Accidental human infection with Plasmodium cynomolgi bastianellii. PMID- 4207079 TI - Alteration of the liver blood flow and phagocytic activity of the reticuloendothelial system in monkeys infected with Plasmodium knowlesi. PMID- 4207081 TI - Studies on the erythrophagocytosis in rhesus monkeys infected with Plasmodium knowlesi. PMID- 4207078 TI - Levels of plasma immunoglobulins in Malaysians. PMID- 4207083 TI - The effect of Travase on wound healing. PMID- 4207082 TI - The association of neoplastic diseases and mycotoxins in the environment. PMID- 4207085 TI - Human coumarin prothrombin. Chromatographic, coagulation and immunologic studies. PMID- 4207084 TI - Interference with organogenesis and fetal development. PMID- 4207086 TI - Platelet factor 3 activity in washed platelets. PMID- 4207087 TI - Platelets and clot retraction. Effect of divalent cations and several drugs. PMID- 4207088 TI - [Treatment of severe diabetic ketoacidosis with intravenous insulin]. PMID- 4207089 TI - [Calcium metabolism in chronic uraemia and in patients on chronic intermittent haemodialysis (author's transl)]. PMID- 4207090 TI - [Effect of temperature, pH and thio-tepa on tumour take rates and thymidine incorporation in ascites tumour cells (author's transl)]. PMID- 4207091 TI - [Alteration of the fractional composition and antigenic structure of botulin toxin E in the process of detoxication]. PMID- 4207092 TI - [A study of the protective antigen of B. anthracis for the purpose of using it in diagnosis]. PMID- 4207093 TI - [The feasibility of using jet injector BIP-4 for immunization of laboratory animals with STI anthrax vaccine]. PMID- 4207094 TI - [Participation of cholera species-specific O-antigen in the passive hemagglutination reaction]. PMID- 4207095 TI - [Fractionation of S. typhi Vi-antigen preparations by the gel filtration method on sephadex G-200]. PMID- 4207096 TI - [The experimental foundation underlying several problems in the enteral method of vaccination. IV. The possibility of using antigen complexes from paratyphoid A bacteria as components of enteral vaccines]. PMID- 4207097 TI - [The antigenic structure of Staphylococcus aureus (review)]. PMID- 4207098 TI - [The mechanism of action of vaccine therapy in experimental brucellosis]. PMID- 4207100 TI - Prostaglandins--basic and clinical considerations. PMID- 4207099 TI - The cephalic arterial system in insectivores, primates, rodents and lagomorphs, with special reference to the systematic classification. PMID- 4207102 TI - [New species of coccidia from the bat (Nyctalus noctula)]. PMID- 4207101 TI - Carbamate resistance in Musca domestica nebulo. PMID- 4207103 TI - A comparison of the life cycles of Toxoplasma and Hepatozoon, with reference to the general phenomenon and the role of cyst formation in the Coccidia. PMID- 4207104 TI - [The influence of the purity of the standard on the results of determining tetracyline activity using two test cultures]. PMID- 4207105 TI - [The effect of neotelomycin on the cytoplasmic membranes of bacteria]. PMID- 4207106 TI - A double-blind trial of long-term lithium therapy in mental defectives. PMID- 4207107 TI - [Ectopic opening of the common bile duct in a gastric diverticulum. Gastric ulcer]. PMID- 4207108 TI - The toxicity of polychlorinated polycyclic compounds and related chemicals. PMID- 4207109 TI - Uptake of the yolk protein, lipovitellin, by developing crustacean oocytes. PMID- 4207111 TI - Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. I. Dependence upon ecdysone concentration. PMID- 4207110 TI - Effects and interactions of juvenile hormone and beta-ecdysone on Drosophila imaginal discs cultured in vitro. PMID- 4207112 TI - Dependence of transdetermination frequency on the developmental stage of cultured imaginal discs of Drosophila melanogaster. PMID- 4207113 TI - [Disturbances of the complement system in renal failure and the influence of amino acid substitution (author's transl)]. PMID- 4207114 TI - [Comparative study of the sensitivity and specificity of various methods used in detection of pulmonary tuberculosis]. PMID- 4207115 TI - Intracistronic mapping of electrophoretic sites in Drosophila melanogaster: fidelity of information transfer by gene conversion. AB - A convenient method is described for the intracistronic mapping of genetic sites responsible for electrophoretic variation of a specific protein in Drosophila melanogaster. A number of wild-type isoalleles of the rosy locus have been isolated which are associated with the production of electrophoretically distinguishable xanthine dehydrogenases. Large-scale recombination experiments were carried out involving null enzyme mutants induced on electrophoretically distinct wild-type isoalleles, the genetic basis for which is followed as a nonselective marker in the cross. Additionally, a large-scale recombination experiment was carried out involving null enzyme rosy mutants induced on the same wild-type isoallele. Examination of the electrophoretic character of crossover and convertant products recovered from the latter experiment revealed that all exhibited the same parental electrophoretic character. In addition to documenting the stability of the xanthine dehydrogenase electrophoretic character, this observation argues against a special mutagenesis hypothesis to explain conversions resulting from allele recombination studies. PMID- 4207116 TI - The genetic structure of natural populations of Drosophila melanogaster. XI. Genetic variability in a local population. AB - Six hundred and ninety-one second chromosomes were extracted from a Raleigh, North Carolina population, and the following experimental results were obtained: (1) Salivary gland chromosomes of all lines were observed and the number of inversion-carrying chromosomes was 130, among which 76 carried In(2R)NS, 36 carried In(2L)t, 4 carried In(2L)t and In(2R)NS, and 14 carried different kinds of rare inversions. (2) Viabilities of homozygotes and heterozygotes were examined. The frequency of lethal-carrying chromosomes was 275/691 (or 0.398):70/130 (or 0.538) in inversion-carrying chromosomes and 205/561 (or 0.365) in inversion-free chromosomes. The former is significantly higher than the latter. The average homozygote viability was 0.4342 including lethal lines and 0.7163 excluding those, the average heterozygote viability being 1.0000. The detrimental load to lethal load ratio (D:L ratio) was 0.334/0.501 = 0.67. The average viability of lethal heterozygotes was less than that of lethal-free heterozygotes, significantly in inversion-free individuals but not significantly so in inversion-carrying individuals. Inversion heterozygotes seem to have slightly better viability than the inversion-free heterozygotes on the average, but not significantly so. (3) The average degree of dominance of viability polygenes was estimated to be 0.293 +/- 0.071 for all heterozygotes whose component chromosomes had better viabilities than 0.6 of the average heterozygote viability, 0.177 +/- 0.077 for inversion-free heterozygotes and 0.489 +/- 0.082 for inversion heterozygotes. (4) Mutation rates of viability polygenes and lethal genes were estimated on the basis of genetic loads and average degrees of dominance of lethal genes and viability polygenes. Estimates were very close to those obtained by direct estimation. (5) Possible overdominance and epistasis were detected, but the magnitude must be very small. (6) The effective size of the population was estimated to be much greater than 10,000 by using the allelism rate of lethal-carrying chromosomes (0.0040) and their frequency.-On the basis of these findings and the comparison with the predicted result (Mukai and Maruyama 1971), the mechanisms of the maintenance of genetic variability in the population are discussed. PMID- 4207117 TI - An ultrastructural study of the response of Blatella germanica (Orthoptera: Blattidae) to the nematode Abbreviata caucasica (Spirurida: Physalopteridae). PMID- 4207118 TI - Induction of sexual reproduction in Opalina sudafricana by injecting its host Bufo regularis with gibberellic acid. PMID- 4207119 TI - Duration and specificity of sodium cromolyn on allergen inhalation challenges in asthmatics. PMID- 4207120 TI - Human carbonic anhydrases. XII. The complete primary structure of the C isozyme. PMID- 4207121 TI - Kinetics of cross-linking of peptidoglycan in Bacillus megaterium. PMID- 4207122 TI - Purification and properties of L-lysine monooxygenase from Pseudomonas fluorescens. PMID- 4207123 TI - Regulatory properties of the flavoprotein L-lysine monooxygenase. PMID- 4207124 TI - Vascularization and the gliding mechanism of free flexor-tendon grafts inserted by the silicone-rod method. PMID- 4207125 TI - Steinmann-pin fixation in the treatment of unstable fractures of the ankle. PMID- 4207126 TI - Effect of tolbutamide on the metabolism of Tetrahymena. PMID- 4207127 TI - The mammalian pars intermedia: a review of its structure and function. PMID- 4207128 TI - Blood-group-like substances in some marine invertebrates. 3. Glycoproteins with blood-group A specificity in the cephalopods Sepia officinalis L. and Loligo vulgaris Lam. PMID- 4207129 TI - Functional organization of a visual area in the posterior bank of the superior temporal sulcus of the rhesus monkey. AB - 1. Anatomical studies have shown the cortex of the posterior bank of the superior temporal sulcus to receive a projection from visual cortical areas, including areas 17, 18 and 19. In this paper the response of single neurones in this area to simple visual stimulation is reported. Ten monkeys were studied.2. A clear but relatively crude topographic representation of the visual field was found. There was a large variation in the size of the receptive fields of individual cells, even in a single penetration. Some cells, with the central parts of their receptive fields located from between 1 and 5 degrees from the centre of gaze had receptive fields averaging about 10 degrees x 10 degrees or even larger. Other cells with central receptive fields had much smaller field sizes.3. Two main types of neurones were encountered, with subdivisions within each type. The first type responded to movement irrespective of form. These could be subdivided into neurones which responded to movement in any direction within the receptive field and neurones which responded to movement in one direction only (directionally selective neurones). Another type of cell was responsive to both contour and movement, much like the complex and lower order hypercomplex cells. Almost all such neurones were directionally selective.4. In oblique penetrations through this cortical region, there tended frequently to be an orderly shift in preferred directions of motion, thus suggesting the possibility of a columnar organization for movement.5. Combined anatomical (degeneration) and electrophysiological experiments showed that these types of neurones are found in those regions of the posterior bank of the superior temporal sulcus receiving a direct projection from area 17. PMID- 4207130 TI - Ionic mechanism for the photoreceptor potential of the retina of Bufo marinus. AB - 1. Membrane potentials were recorded from single rods in the isolated retina of Bufo marinus while the ionic composition of the extracellular medium was rapidly changed. Substitution of 2 mM aspartate(-) for Cl(-) produced a prompt depolarization of horizontal cells, but no modification of either resting potential or response to light in receptor cells. This implies that feed-back from horizontal cells to receptor cells was not active.2. During substitution of choline(+) or Li(+) for Na(+), and during isosmotic substitution of sucrose for NaCl, the resting potential of receptor cells became more negative and responses to light were abolished. During exposure to K(+)-free medium, the resting potential became slightly more negative and the responses to light became larger and developed small after-depolarizations. Exposure to [K(+)](out) of four times normal resulted in permanent diminution of response magnitude and permanent change of response waveshape. Removal of Mg(2+), four times normal [Mg(2+)](out) or substitution of methylsulphate(-) for Cl(-) had no effect on resting potential or responses to light. With the exception of the small effects seen with altered [K(+)](out) these results are consistent with the receptor potential being generated by a light-induced decrease of membrane conductance to Na(+).3. Exposure to decreased [Ca(2+)](out) caused both a depolarization of the receptor membrane in the dark and an increase in the magnitude of the maximal response that could be evoked by a test stimulus. The magnitude of the increase in response equalled the magnitude of the depolarization. Exposure to increased [Ca(2+)](out) or steady background light caused both a steady hyperpolarization and a decrease in the magnitude of the maximal response that could be evoked by a test stimulus. For steady hyperpolarizations greater than 3.5 mV, whether caused by elevated [Ca(2+)](out) or steady background light, the decrease in response magnitude exceeded the magnitude of the hyperpolarization. These results imply that externally applied Ca(2+) ions mimic the effects of steady background lights, but the applied Ca(2+) ions must do more than merely decrease membrane conductance to Na(+). PMID- 4207131 TI - The effect of sodium and calcium ions on the release of catecholamines from the adrenal medulla: sodium deprivation induces release by exocytosis in the absence of extracellular calcium. AB - 1. Perfusing bovine adrenal glands with Na(+)-free Locke solution for 15-40 min did not modify the increase in the release of catecholamines from glands stimulated by acetylcholine. However, after 80-100 min of perfusion with Na(+) free solution, the response to acetylcholine stimulation was decreased or abolished.2. Immediately after switching the perfusion medium to Na(+)-free solution, there was a sharp increase (6-10 times over control values) in catecholamine output.3. Graded substitution of Na(+) in the perfusion fluid enhanced the output of catecholamines. This increase in the output of amines was linearly related to the logarithm of the extracellular Na(+) concentration.4. The release of catecholamines in the absence of Na(+) was not reduced by the presence of atropine and hexamethonium nor by the omission of Ca(2+) in the presence of EDTA or EGTA.5. Excess of Mg(2+) in the perfusion fluid reduced (10 mM-Mg(2+)) or blocked (20 mM-Mg(2+)) the increase in the output of catecholamines induced by Na(+) deprivation in the presence or absence of extracellular Ca(2+).6. Na(+) deprivation induced release of catecholamines during perfusion of the glands with depolarizing concentrations (56 mM) of K(+).7. In the presence or the absence of extracellular Ca(2+), the increase in the output of catecholamines induced by Na(+) deprivation was accompanied by an increase in the output of dopamine beta hydroxylase, but not of lactate dehydrogenase. In addition, during perfusion with Ca(2+) free solution, Na(+) deprivation induced a parallel increase in both catecholamine and adenosine triphosphate outputs.8. The ratios of catecholamines to dopamine beta-hydroxylase and catecholamines to adenosine triphosphate determined in the perfusates collected from glands during perfusion with Na(+) free medium were similar to those measured in the soluble contents of isolated chromaffin granules. These results provided biochemical evidence in favour of exocytosis as the mechanism of secretion during Na(+) deprivation. PMID- 4207133 TI - Gonococcal colony types. PMID- 4207132 TI - Tuberculosis in a family day-care home. Report of an outbreak and recommendations for prevention. PMID- 4207134 TI - Editorial: The nondiscriminant gonococcus. PMID- 4207135 TI - Infective endocarditis. A review of selected topics. PMID- 4207136 TI - Bacteremia caused by gram-negative bacilli. PMID- 4207137 TI - [Letter: Continuous enteral resuscitation of major malnutrition states and classic naso-gastric tube alimentation]. PMID- 4207138 TI - [An intractable case of petit mal. Effects of clomipramine]. PMID- 4207139 TI - [Retroperitoneal fibrosis. Apropos of a case caused by methysergide and complicated by femoral arteriopathy and tricuspid insufficiency]. PMID- 4207140 TI - Amniotic fluid assay as an index for gestational age and fetal development in the baboon. PMID- 4207141 TI - Ultrasonic aspiration transducer for management of Rh incompatibility. PMID- 4207142 TI - A dose-rate effect in the ultraviolet inactivation of bacterial spores. PMID- 4207143 TI - [Serum haptoglobin levels in Rh-negative women receiving prophylactically anti-Rh (D) immunoglobulin following labor]. PMID- 4207144 TI - [A case of heterotopic ossification of a laparotomy cicatrix]. PMID- 4207145 TI - Comparative investigations on several immunodiffusion methods for Australia antigen detection. II. Electroimmunodiffusion. PMID- 4207146 TI - Studies on the sensitivity of a passive hemagglutination test in the detection of antimeasles antibodies. PMID- 4207148 TI - Letter: False positive reactions in the electroimmunodiffusion technique for Australia antigen detection. PMID- 4207147 TI - Investigations on human antibodies against Australia antigen. PMID- 4207149 TI - Immunochemical study of the interaction between staphylococcal protein A, rabbit antistaphylococcal sera, and selected sera from nonimmunized animals. PMID- 4207150 TI - Immunoglobulins in feces from infants fed human or bovine milk. PMID- 4207151 TI - On the frequency of valine in position 2 of the V k3 subgroup. PMID- 4207152 TI - The principle of immunopotentiation in treatment of rheumatoid arthritis: effect of transfer factor. PMID- 4207155 TI - Intestinal cystoplasty. Long-term functional result. PMID- 4207154 TI - Ureteral duplication and prostatic disease. PMID- 4207153 TI - Summary of recent abstracts. VII. Rickettsial diseases. PMID- 4207156 TI - Diverticula of female urethra. Diagnostic importance of postvoiding film. PMID- 4207160 TI - Water movement in the vitreous body, evaluated experimentally and theoretically. PMID- 4207158 TI - Enhancement of microsomal drug hydroxylation and glucuronidation in rat liver by phenobarbital and 3-methylcholanthrene in combination. PMID- 4207157 TI - Condyloma acuminatum of male urethra. Successful management with 5-fluorouracil. PMID- 4207159 TI - Activation and inactivation of membrane-bound UDP-glucuronosyltransferase by organic solvents in vitro. PMID- 4207161 TI - Placental transfer of a cephalosporin derivative (C 36'278-Ba). PMID- 4207162 TI - Bacteriostatic action of middle ear exudate and blood leucocytes. PMID- 4207163 TI - Effects of opioid narcotic drugs on energy reserves of skeletal muscle. I. Glycogen. PMID- 4207164 TI - Concerning the role of zinc in the antitumor activity of 3-ethoxy-2 oxobutyraldehyde bis(thiosemicarbazonato) zinc(II) and related chelates. PMID- 4207165 TI - [Plaque production in vero cells by ECHO virus]. PMID- 4207167 TI - [Effects of saccharo 1,4 lactone, EDTA and p-nitrophenol on the UDP-glucuronyl transferase activity of rat liver microsomes]. PMID- 4207166 TI - [Sensitivity of vero cells to prototype ECHO viruses and to those of 1st isolation. Hemagglutinin production capacity]. PMID- 4207168 TI - [Immunochemical behavior of free and fixed antibodies during auto-antibody induced hemolytic anemia]. PMID- 4207169 TI - [Identification of ABO and Rhesus system antibodies from amniotic fluid cells]. PMID- 4207170 TI - [Activation roles of frontal ocellus in the sexual competition between Drosophila melanogaster males]. PMID- 4207171 TI - [Bradykinin and in vitro prostaglandin biosynthesis]. PMID- 4207172 TI - Effects of concentration of volatile metabolites from bacteria and germinating seeds on fungi in the presence of selective absorbents. PMID- 4207173 TI - Immunological response of guinea pigs experimentally infected with Histoplasma duboisii. PMID- 4207174 TI - Dimension control in bacteria. PMID- 4207175 TI - The isolation of blue-green bacteria in pure culture. PMID- 4207176 TI - Sympathetic and parasympathetic components of reflex tachycardia induced by hypotension in conscious dogs with and without heart failure. PMID- 4207178 TI - The genetics of hereditary angioedema: a hypothesis. PMID- 4207177 TI - Cystic fibrosis: synthesis of ciliary inhibitor by amniotic cells. PMID- 4207179 TI - An analysis of the development program in relation to RNA metabolism in the ciliate Stylonychia mytilus. PMID- 4207180 TI - Development of the temperature-sensitive homoeotic mutant ophthalmoptera of Drosophila melanogaster. PMID- 4207181 TI - Development of early behaviors in neonatal squirrel monkeys and cotton-top tamarins. PMID- 4207183 TI - [Orthology and pathology of the human placenta--conclusion. 3. Pathology of the placenta and placental changes in special diseases during the last 3d of pregnancy]. PMID- 4207182 TI - [A neurophysiologic analysis of the effect of insulin on the central nervous system]. PMID- 4207184 TI - Enhancing factor on anti-hapten antibody response released from PPDs-stimulated tubercle bacilli-sensitized cells. PMID- 4207185 TI - Purification and properties of the C4 inactivator from nurse shark serum. PMID- 4207186 TI - Structural features of pig IgA. PMID- 4207187 TI - Two new inhibitory activities in blood of mice with delayed hypersensitivity, after challenge with specific antigen. AB - In addition to the activities associated with migration inhibitory factor and type II interferon, two other inhibitory activities have been found in the sera of mice infected intravenously with BCG and 3 weeks later challenged intravenously with old tuberculin. Growth of three bacteria, Streptococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, and one yeast, Candida albicans, was inhibited in vitro by a factor or factors in the serum. Also, hematopoiesis of mouse bone marrow cells in a soft agar medium was suppressed by the serum. PMID- 4207189 TI - Respiratory immune response to aerosolized keyhole limpet hemocyanin in primate lungs. AB - Methodology for delivery of antigen to the lower respiratory tract of rhesus monkeys and the recovery of respiratory secretions (RS) by bronchial lavage has been evaluated and has been done on repeated occasions without apparent risk to animals. Rhesus immunoglobulin (Ig)G, IgM, and IgA were identified in RS by their cross-reactivity with human IgG, IgA, and IgM, and relative concentrations of rhesus IgA and IgG could be evaluated in sequential samples of RS and serum (S) by radial immunodiffusion analysis using antiserum specific for human gamma and alpha chains. Administration of keyhole limpet hemocyanin (KLH) by aerosol was compared with intravenous administration of KLH. The aerosol route of administration resulted in IgG, IgM, and IgA antibodies detectable by radio immunodiffusion in RS but only IgG antibodies in serum. After separate sequences of exposure to KLH delivered to the lung, a secondary type of immune response in the lung appeared as indicated by time of appearance and height of antibody titers. Antibody titers against KLH were estimated by passive hemagglutination of tanned sheep red cells coated with KLH, and anti-KLH titers were comparatively higher in RS of animals immunized by the respiratory route. Treatment of RS and S with 2-mercaptoethanol resulted in reduction of hemagglutination titers of both S and RS, but the degree of reduction varied in different samples and was independent of whether or not the S and RS were collected simultaneously. These results indicate that at least part of the antibody response to aerosolized KLH in rhesus monkeys occurs in the lung and that antibodies may appear in all three immunoglobulin classes in this response. PMID- 4207188 TI - Detection of nonspecific resistance to Listeria monocytogenes in rabbits infected with Treponema pallidum. AB - Several lines of evidence suggest that cell-mediated immunity (CMI) is suppressed in the early stages of infection caused by Treponema pallidum and becomes activated at the time that latency is induced. In the studies reported in this paper, rabbits were infected intravenously with T. pallidum and subsequently challenged with Listeria monocytogenes. Enhanced ability to suppress the growth of Listeria was detected in their livers between 3 and 5 weeks after infection with T. pallidum, corresponding to the onset and regression of the generalized syphilitic eruption. A second infection of T. pallidum 4 weeks after the first, at a time when suppression was beginning to wane, prolonged the listericidal activity. These observations support the hypothesis that infection by T. pallidum stimulates CMI, which, in turn, may play a role in inducing latency. PMID- 4207190 TI - Occurrence of quinovosamine in lipopolysaccharides of Brucella species. AB - Lipopolysaccharides obtained from Brucella abortus, B. melitensis, and B. suis, but not B. canis, were found to contain amino sugars identified as glucosamine and quinovosamine by cation exchange and thin-layer cellulose chromatography and ninhydrin degradation. PMID- 4207191 TI - Replication of macronuclear DNA in the cytoplasm of Tetrahymena pyriformis. PMID- 4207192 TI - Observations implicating an extracellular enzymic mechanism of control of bone morphogenesis. PMID- 4207193 TI - Distribution of peroxidase activity in Tetrahymena pyriformis mitochondria. PMID- 4207194 TI - Giant lysosomes in cultured monkey kidney cells. PMID- 4207195 TI - Immunochemistry of counterimmunoelectrophoresis and the effect of electroendosmotic flow on reactivity. PMID- 4207196 TI - Spontaneous rosettes as a T-lymphocyte marker: a modified method giving consistent results. SRBC rosettes. PMID- 4207197 TI - Detection and quantitation of chicken antibodies to streptococcal carbohydrate by high-salt reverse radial immunodiffusion. PMID- 4207198 TI - Heterogeneity of RNA polymerase in Escherichia coli. I. A new holoenzyme containing a new sigma factor. PMID- 4207199 TI - Blood levels of free and bound thyroid hormones. PMID- 4207200 TI - On earlier states of the biochemical system. PMID- 4207202 TI - Cytoplasmic factors in the gonads of Culex pipiens complex mosquitoes. PMID- 4207201 TI - Antagonism of ethanol narcosis by thyrotropin releasing hormone. PMID- 4207203 TI - [Experiences with the vena-cava catheter]. PMID- 4207206 TI - Evaluation of systemic steroid treatment in children with asthma. PMID- 4207204 TI - Transfection of Bacillus subtilis with bacteriophage H1 DNA: fate of transfecting DNA and transfection enhancement in B. subtilis uur+ and uur- strains. PMID- 4207205 TI - The significance of brucella antibodies in patients in a rural area. PMID- 4207207 TI - Renal blood flow and function following suprarenal ligation of the inferior caval vein. An experimental study in the rabbit. PMID- 4207208 TI - An anthrax outbreak in Berkshire. PMID- 4207209 TI - [Immunochemical method of studying the biosynthesis of intracellular proteins]. PMID- 4207210 TI - [Study of the blood serum proteins during parenteral feeding of a fatty emulsion]. PMID- 4207212 TI - [Pectin-splitting and lipid-oxidizing enzymes in food processing]. PMID- 4207211 TI - [Comparison of the antigenic properties of the immunoglobulins in the human intestinal contents with homologous serum IgG, IgA and Igm]. PMID- 4207213 TI - Interaction between azotobacter chroococcum, bacillus megaterium var. phosphaticum and rhizobium sp. PMID- 4207214 TI - [Characterization of an urea and ammonia utilization-deficient mutant of Hydrogenomonas eutropha H 16 (author's transl)]. PMID- 4207215 TI - [Aspergillus flavus as an infectious microorganism in the citric acid fermentation. 2. The suppression of Aspergillus flavus in the citric acid fermentation (author's transl)]. PMID- 4207216 TI - The effect of certain nitro-herbicides on the growth of some soil-inhabiting fungi. PMID- 4207217 TI - An apparatus for the microslide immunodiffusion. PMID- 4207218 TI - Intracortical distribution of renal blood flow during saline infusion in dogs. PMID- 4207219 TI - Influence of aldosterone on active sodium transport by the toad bladder: a kinetic approach. PMID- 4207220 TI - Primate biliary physiology. IX. Effects of acute biliary obstruction on biliary lipid metabolism in the monkey. PMID- 4207221 TI - Kinetics of kinin release in canine plasma. PMID- 4207222 TI - Nitroglycerin and chromonar on small-vessel blood content of the ventricular walls. PMID- 4207224 TI - Changes in the subunit structure of Bacillus subtilis RNA polymerase during sporulation. PMID- 4207223 TI - [Transport of 17beta-estradiol and 7,12-dimethylbenz(a)anthracene into uterus nuclei in vitro (author's transl)]. PMID- 4207225 TI - Transcriptional systems in eukaryotic cells. PMID- 4207226 TI - The stringent response--21 years on. PMID- 4207227 TI - [Study of Australia antigen in primary liver cancers. Correlation with alpha fetoprotein]. PMID- 4207228 TI - A dermatosis specifically associated with a tumour of pancreatic alpha cells. PMID- 4207229 TI - New concepts in the management of mycosis fungoides. PMID- 4207230 TI - The use of the hamster stomach in vitro as an assay preparation for prostaglandins. AB - 1. Hamster stomach strips in vitro are useful test preparations for the assay of prostaglandins E and F in the nanogram concentration range. Three-minute cycles can be used for long periods without spontaneous contractions or significant base line instability.2. The mean percentage error and the precision index of six 4 point assays of prostaglandin E(2) were 7.8 and 0.057, respectively.3. The relative sensitivity to different prostaglandins was E(2)/E(1) approximately 1, E(2)/F(1alpha) approximately 65 and E(2)/A(1) approximately 400.4. These preparations were relatively insensitive to 5-hydroxytryptamine (prostaglandin E(2)/5-HT approximately 20,000) and histamine (prostaglandin E(2)/histamine approximately 200).5. These results suggest that the hamster stomach preparation can be used to differentiate between 5-hydroxytryptamine and prostaglandins. PMID- 4207231 TI - A kallikrein-like substance in cat nasal secretion. AB - Incubation of cat nasal secretion with cat plasma releases a substance which will contract the cat isolated jejunum, a tissue specifically sensitive to bradykinin and similar peptides. The smooth muscle stimulating activity of the incubate is potentiated and prolonged 'by the addition of the kininase inhiibitor, EDTA. From the results it is concluded that the incubation of cat nasal secretion and plasma releases a kinin-like substance, and that this kinin may have a role in the secretory and vasomotor activity of the nasal mucosa. PMID- 4207232 TI - Response of flocculus Purkinje cells to adequate vestibular stimulation in the alert monkey: fixation vs. compensatory eye movements. PMID- 4207233 TI - Editorial: Diagnosis of thyroid diseases. PMID- 4207236 TI - Corynebacterium, tubercle bacillus and cancer. PMID- 4207235 TI - Thymidine metabolism during normal and compensatory renal growth. PMID- 4207234 TI - Therapeutic efficacy of rifampin in newly detected pulmonary tuberculosis. AB - A comparison was made of the therapeutic efficiency and tolerance of rifampin based regimens and that of the standard triple-drug combination in the treatment of 92 newly diagnosed cases of pulmonary tuberculosis. The three drug regimens investigated were: A, rifampin-INH; B, rifampin-INH-streptomycin; and C, INH-PAS streptomycin. Therapeutic progress was measured in terms of sputum conversion on culture and microscopy. The rifampin combinations produced a somewhat earlier sputum conversion. With regimens containing this potent antibiotic the phenomenon of microscopically-positive but culture-negative specimens was more frequently observed. The tolerance exhibited to the rifampin regimens was far greater than that to the conventional triple-drug combination. Nevertheless, periodic laboratory examinations are essential during rifampin therapy for safe utilization of the drug. An incidental finding of this study was the increase in primary resistance to streptomycin particularly among recent immigrants to Canada. PMID- 4207237 TI - Retinal synaptogenesis in the primate. PMID- 4207238 TI - The inhibitory effect of pentobarbital Na on aqueous humor formation. PMID- 4207239 TI - Chromatographic and biological aspects of DDT and its metabolites. PMID- 4207240 TI - Effects of microquantities of testosterone on the epididymis and accessory glands of the castrated rhesus monkey, Macaca mulatta. PMID- 4207241 TI - Behavioral activities and cardiovascular functions: effects of hexamethonium on cardiovascular changes during strong sustained static work in rhesus monkeys. PMID- 4207243 TI - Prevention of acute pulmonary insufficiency by eriodictyol. PMID- 4207242 TI - The role of the autonomic nervous system in the responses of the perfused canine paw to prostaglandins B1 and B2. PMID- 4207244 TI - The effect of acetazolamide and furosemide on cerebrospinal fluid production and choroid plexus carbonic anhydrase activity. PMID- 4207245 TI - Morphine metabolism in vivo and in vitro by homozygous Gunn rats. PMID- 4207246 TI - Evaluation of the crypt surface adjacent to metal endosseous implants: an electron microscopic study in clinically successful implants. PMID- 4207248 TI - [Histamine content in the maternal and fetal blood in atonic labor]. PMID- 4207247 TI - Protease-sensitive transfection of Bacillus subtilis with bacteriophage GA-1 DNA: a probable case of heterologous transfection. AB - The host bacterium of bacteriophage GA-1, Bacillus sp. G1R, was compared with respect to its taxonomic relationship to Bacillus subtilis, B. licheniformis, and B. pumilis. The physiological-biochemical properties of Bacillus sp. G1R are equal to those of B. licheniformis, but the thermal denaturation midpoint of G1R DNA differs by 3 C and the buoyant density by 0.005 g/cm(3) from that of B. licheniformis. Transformation with G1R donor DNA was neither observed in B. licheniformis nor in B. subtilis-competent recipients. Bacteriophage GA-1 shows neither infectivity on B. licheniformis nor on B. subtilis. However, infection of competent B. subtilis cultures with phenol-extracted GA-1 DNA results in the production of infective GA-1 particles. The transfecting activity of GA-1 DNA is destroyed by treatment with proteolytic enzymes. Resistance of transfecting DNA to inactivation by trypsin develops earlier than that to inactivation by DNase. Protease-treated GA-1 DNA competes with transforming DNA to approximately the same extent as does untreated GA-1 DNA, suggesting that uptake of GA-1 DNA is not affected by protease treatment. CsCl density gradient centrifugation reveals that the density of trypsinized GA-1 DNA is 0.004 g/cm(3) greater than that of untreated DNA. PMID- 4207249 TI - Psychomotor epilepsy in childhood. PMID- 4207250 TI - Diagnosis and treatment of childhood myoclonic seizures. PMID- 4207252 TI - [Differential diagnosis of the chief forms of growth retardation using digital computers]. PMID- 4207253 TI - [Comparative double blind study of Stabicilline and Bactrim in the treatment of acute desmodontitis of infectious origin]. PMID- 4207251 TI - [Lactic acidosis in diabetes mellitus (review of the literature)]. PMID- 4207254 TI - [Animal experiments on direct capping. Comparison of the standard combination Ca(OH)2-corticoid-antibiotic paste and other potential capping materials]. PMID- 4207255 TI - Plasma transferrin in Singapore women during pregnancy. PMID- 4207257 TI - Dicephalus, spina bifida, Arnold-Chiari malformation and duplication of thoracic organs in a calf. Description of the case and critical discussion of the pathogenesis of the Arnold-Chiari malformation. PMID- 4207258 TI - Blood and milk levels of chloramphenicol in normal and mastitic cows and ewes after intramuscular administration of chloramphenicol and chloramphenicol sodium succinate. PMID- 4207259 TI - [An eye abnormality in a beagle]. PMID- 4207256 TI - The role of infection on wound healing. PMID- 4207260 TI - [Permeability disorders in the porcine brain. Occurrence of exudations in random sample material]. PMID- 4207261 TI - Multiple myeloma of IgA type in a dog. PMID- 4207262 TI - Prenatal development and activity of the thyroid gland of the buffalo. PMID- 4207263 TI - Diabetes mellitus with pancreatic atrophy in antelopes in the Amsterdam zoo. PMID- 4207264 TI - N-bromosuccinimide protects chick embryos against the lathyrogenic effect of isonicotinic acid hydrazide. PMID- 4207265 TI - [Construction and selection: arguments against morphologically shortened selectionism]. PMID- 4207266 TI - Experimental iris sutures in the monkey. PMID- 4207267 TI - Puerperal morbidity and internal fetal monitoring. PMID- 4207268 TI - Placental transfer and distribution of nicotine in the pregnant rhesus monkey. PMID- 4207269 TI - Venous thrombosis on prosthetic surfaces. Evolution and blood coagulation studies in a nonhuman primate model. AB - Thrombi deposited on prosthetic devices in the superior vena cava of the rhesus monkey were studied by morphologic and biochemical technics. Glass or silicone coated glass (SCG) rings were implanted for 30 minutes to 14 days. Thrombus was deposited on the surface of each prosthetic device, and deposition was much greater and more rapid on glass surfaces than on SCG surfaces. On SCG surfaces, initial deposits consisting of single platelets, small platelet aggregates and erythrocytes were seen by scanning electron microscopy. These were followed by larger platelet aggregates, fibrin and, much later, leukocytes. Transmission electron micrographs revealed disintegration of the platelets forming aggregates and an osmiophilic deposit on the prosthetic surface. Shortened partial thromboplastin times were observed in all test animals but the sham-operated one, and therefore may be predictive of thrombus formation. PMID- 4207270 TI - Pancreatic beta cell replication induced by glucocorticoids in subhuman primates. AB - Pancreatic islets were studied by means of light microsocpy, autoradiography and electron microscopy in untreated Macaca cyclopis monkeys and after the administration of large quantities of adrenal glucocorticoids. Mild hyperglycemia and profound elevations of serum immunoreactive insulin were induced by glucocorticoid injections of 1 to 3 weeks duration, with a gradual return to pretreatment levels within 2 months after cessation of treatment. Morphologic alterations included degranulation and hyperplasia of pancreatic beta cells. These were noted in association with increased numbers of labeled islet cells after the administration of (3)H-thymidine and beta cells undergoing mitotic division, and could be correlated directly with the magnitude of serum insulin elevation. Evidence of acinar-islet or duct-islet cell transformation was absent. Beta cell regranulation and the twofold increase in extractable pancreatic insulin which followed the cessation of injections demonstrated the survival and functional integrity of the newly formed beta cells. PMID- 4207271 TI - Pulmonary intravascular leukocyte sequestration. A potential mechanism of lung injury. PMID- 4207272 TI - Mycobacterial skin tests in humans 12 years after infection with Mycobacterium marinum. PMID- 4207273 TI - Ethambutol-isoniazid versus streptomycin-ethambutol-isoniazid in original treatment of cavitary tuberculosis. PMID- 4207274 TI - Letter: Urethral burning as a side effect of cromolyn sodium. PMID- 4207275 TI - Skeletal reactions to neoplasms. PMID- 4207276 TI - Small-sample blood culture method for identification of bacteria in central arterial and peripheral blood. AB - A blood culture technique that utilized small arterial blood samples or peripheral capillary blood was tested in beagle dogs and pig-tailed macaque monkeys. A bolus of 2.0 x 10(7)Escherichia coli (ATCC 25922) was injected intravenously into five animals of each species. Blood samples were taken before injection of the organisms and 10, 15, 20, 30, 60, and 120 min after injection. Arterial blood samples (2.0 and 0.2 ml) and peripheral capillary samples (0.14 ml) were taken at each sampling time. Pour plates were prepared from arterial blood for colony counts. All three blood sampling methods were equally effective in detecting sepsis when 10 or more organisms per ml of blood were present. Below this level, the 2.0-ml sample was more effective. Contamination of the peripheral sample with air or skin contaminants was a problem. PMID- 4207277 TI - New gas chromatographic characterization procedure: preliminary studies on some Pseudomonas species. AB - Strains of saccharolytic and nonsaccharolytic Pseudomonas species were examined by a new single-step gas chromatographic characterization procedure. Cells were digested in a methanolic solution of tetramethylammonium hydroxide pentahydrate, and the digestates were subjected to gas-liquid chromatographic analysis. The chromatograms were examined for similarities and differences in their overall patterns. A single component was defined for use as an internal qualitative and quantitative standardizing component in order to develop relative retention time relative peak height profiles of each organism. Comparison of these profiles enabled the characterization of strains of Pseudomonas aeruginosa, P. putida, P. cepacia, P. pseudomallei, P. stutzeri, P. pseudoalcaligenes, P. alcaligenes, P. diminuta, P. denitrificans, and P. acidovorans. The P. maltophilia and P. putrefaciens digestates showed chromatograms which were superficially similar yet easily distinguished as belonging to different species. The chromatograms of these two organisms were very different from those of other pseudomonads. PMID- 4207278 TI - Polygalacturonate lyase production by Bacillus subtilis and Flavobacterium pectinovorum. AB - Nutritional factors relating to the production of polygalacturonate lyases by strains of Bacillus subtilis and Flavobacterium pectinovorum were examined. Studies were carried out in shake flask cultures. In the case of B. subtilis the enzyme was produced constitutively, whereas in the case of F. pectinovorum it was only produced in quantity in the presence of pectic substances. Glucose was the most suitable carbon source for production of the polygalacturonate lyase of B. subtilis; of the nitrogen sources examined, the highest activities per milliliter of supernatant and per milligram of cells were obtained with glutamine and ammonium sulfate, respectively. The pattern of enzyme production and growth was similar although enzyme production ceased at pH 5.3. Sodium polypectate was the best inducer of polygalacturonate lyase with F. pectinovorum. Highest activity per milliliter of cell-free supernatant was obtained with skin milk powder as nitrogen source, although ammonium sulfate gave highest enzyme production per unit of biomass. Growth of F. pectinovorum occurred between pH 5.7 and 7.2. Enzyme production occurred during active growth and was independent of the pH of the medium. PMID- 4207279 TI - Stable mycoplasma antigen preparations for indirect hemagglutination tests. AB - In immunological studies of mycoplasmas, the use of glutaraldehyde for the fixative makes it possible to use erythrocytes from commercially available defibrinated sheep blood. It eliminates the necessity of having to screen blood from individual sheep to obtain a suitable source of erythrocytes, as when employing tannic acid for fixation and sensitization. The chemical bonding of soluble mycoplasma proteins to glutaraladehyde-fixed sheep erythrocytes by bis diazotized 3,3'dimethoxy derivative, benzidine, yields preparations that are satisfactory antigens for performing the indirect hemagglutination test by the microtiter technique. The antigenic preparations are satisfactory for use after storage at 4 or -10 C for many months. Incorporation of 5% glycerine in the final suspending milieu makes it possible to obtain uniform suspensions of the fixed and sensitized sheep erythrocytes after freezing and after repeated freezing and thawing. Proteins from Mycoplasma arthritidis and M. hominis have been coupled to glutaraldehyde-fixed erythrocytes by diazotization. The last mentioned preparation detected the presence of antibodies in titers greater than 1:10 in 37% of 237 pregnant women whose ages ranged between 20 and 30 years. There was no correlation between the presence of specific antibodies in the blood and the isolation of M. hominis from the cervical canal. PMID- 4207281 TI - Inhibition of aflatoxin production and tentative identification of an aflatoxin intermediate "versiconal acetate" from treatment with dichlorvos. AB - In general, aflatoxin production by Aspergillus flavus and A. parasiticus was greatly reduced in vitro in the presence of the insecticide dichlorvos. Reduction in yield of the toxins was accompanied by the apperance of a previously unidentified orange pigment. Spectral analyses of the pigment and of its methylated and acetylated derivatives indicated the compound to be versiconal acetate (IV). The data suggest that IV is an intermediate in the metabolic cycle that may terminate in the production of aflatoxin or of the versicolorins, or both. Dichlorvos apparently inhibits biosynthesis of the difurano ring structure common to the aflatoxins and the versicolorins. PMID- 4207280 TI - Slide agglutination method for the serological identification of Neisseria gonorrhoeae with anti-gonococcal antibodies adsorbed to protein A-containing staphylococci. AB - A rapid slide agglutination test has been developed for the identification of Neisseria gonorrhoeae that are primarily detected as oxidase-positive colonies in gonococcal cultures. The technique is based on the specific nonimmune reactivity between the Fc portion of immunoglobulin (Ig)G and staphylococcal protein A. IgG molecules adsorbed to stabilized staphylococci will thereby become oriented with their antigen-reactive sites that are directed outwards. Protein A-containing staphylococci with unabsorbed anti-gonococcal antibodies gave positive co agglutination reactions with gonococci but also with meningococci, some Moraxella, Haemophilus, and Pseudomonas strains. These crossreactions were eliminated by absorption of the anti-gonococcal antiserum with meningococcal and Moraxella organisms prior to the coating of reagent staphylococci. In the routine culture diagnosis of N. gonorrhoeae the use of specific gonococcal reagent staphylococci gave concordant results with fermentation procedures and immunofluorescent techniques. PMID- 4207283 TI - Simplified sugar fermentation plate technique for identification of Neisseria gonorrhoeae. AB - A simplified sugar fermentation technique incorporating (i) a glucose and (ii) a maltose, lactose, and sucrose plate was developed for confirming large numbers of Neisseria gonorrhoeae cultures. PMID- 4207282 TI - Pyocin typing of Pseudomonas aeruginosa: a simplified method. AB - A simplified method has been devised for typing Pseudomonas aeruginosa by pyocin production. Pyocins are produced as strains grow overnight in Trypticase soy broth (without glucose) plus 1% potassium nitrate. Because P. aeruginosa can use nitrate instead of oxygen as a terminal electron acceptor, mechanical shaking is not necessary, nor is induction by mitomycin C. Pyocins can now be produced in screw-cap tubes in a water bath or incubator. A total of 250 strains were tested as possible pyocin indicators, which included 60 strains already used in pyocin typing systems. The final set contained 18 indicators which were chosen because (i) they had clear positive or clear negative reactions, thus eliminating reactions difficult to read, (ii) they had few zones due to bacteriophage lysis, and (iii) they were most sensitive in differentiating clinical isolates of P. aeruginosa. The final typing method was tested in several studies and the results were clear; thus definitive epidemiological conclusions could be made. Because it is simple to perform and easily automated, the new method should have application in many hospitals; however, it should be used only in carefully planned epidemiological studies. The method and its application are described in detail, and some pitfalls are discussed. PMID- 4207284 TI - Carrier cultures of human fetal diploid cells infected with coxsackievirus type B2. PMID- 4207285 TI - Serological characterization of buffalopox virus. PMID- 4207286 TI - Maturation of chloroplast rRNA in Euglena gracilis. PMID- 4207287 TI - A rotor speed dependent crossover in sedimentation velocities of DNA's of different sizes. PMID- 4207288 TI - The synthesis of MS 1 and MS 2 by Bacillus subtilis. PMID- 4207289 TI - Hepatic DNA repair synthesis in rats fed 3'-methyl-4-dimethylaminoazobenzene. PMID- 4207290 TI - Studies on the fluorophore sempervirene and its complexes with DNA. AB - Evidence that the fluorophore sempervirene binds to nucleic acids is presented. The complexes were studied by fluorescence intensity, spectra, decay lifetime, and polarization methods. Both fluorescent and nonfluorescent complexes are formed. The sempervirene is rigidly fixed to DNA. If ethidium bromide and sempervirene are bound to DNA, energy can be transferred from sempervirene to ethidium. Sempervirene is taken up by mammalian cells and appears in the cytoplasm. This unusual new probe should be useful in molecular and cellular investigations. PMID- 4207292 TI - The actions of prostaglandins E2 and F2alpha on human foetal intestine. AB - Human foetal small and large intestine responded to prostaglandins E(2) and F(2alpha), the gestational age of the tissue being between 14 and 26 weeks. The predominant response to both prostaglandins was a contraction of each region of the intestine studied. The response to both prostaglandins was antagonized selectively by poly.phloretin phosphate. PMID- 4207291 TI - The influence of anaesthetics on the increase in the water permeability of the toad bladder induced by vasopressin. AB - 1 Single lobes of the bladder of Bufo marinus were isolated and filled with, and suspended in, oxygenated Ringer solution. The fluid in contact with the outside (serosa) of the lobes had a total osmolarity of 225 m-osmol/litre, and that bathing the inside (mucosa) of 45 m-osmol/litre.2 Osmotic water flow from mucosa to serosa was measured by weighing the lobes every 30 minutes. It was negligible unless vasopressin was added to the serosal bath. Standard concentrations of either 1.25 or 6.25 mu/ml were used to render the bladder lobes permeable to water.3 The presence in the serosal medium of pentobarbitone or thiopentone in concentrations ranging from 0.25 to 2.5 mM, or of chloralose in concentrations ranging from 0.65 to 6.5 mM, diminished the increase in water permeability induced by vasopressin.4 The three anaesthetics exerted similar inhibitory effects on the action of vasopressin from the serosal and from the mucosal surface of the bladder.5 In the presence of a constant high concentration of anaesthetic, increasing the concentration of vasopressin over three orders of magnitude led to stepwise increases of osmotic water flow out of the lobes, although at every dose level the effect of vasopressin was depressed by the anaesthetic. However, it was not completely abolished even if the concentration of vasopressin was close to threshold.6 The increase in water permeability of the bladder induced by 3',5'-adenosine monophosphate (cyclic AMP) was also depressed by the three anaesthetics.7 Possible explanations of the findings are discussed. PMID- 4207293 TI - Treatment of supraglottic cancer by radical high dose radiotherapy. PMID- 4207294 TI - Sensitivity to irradiation of the brain stem. Irradiation myelitis in the treatment of a nasopharynx carcinoma. PMID- 4207295 TI - Non-epithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. A clinicopathologic study. II. Osseous and fibro-osseous lesions, including osteoma, fibrous dysplasia, ossifying fibroma, osteoblastoma, giant cell tumor, and osteosarcoma. PMID- 4207296 TI - Restoration of fertility in sterilized Drosophila eggs by transplantation of polar cytoplasm. PMID- 4207297 TI - Repair of a genetically-caused defect in oogenesis in Drosophila melanogaster by transplantation of cytoplasm from wild-type eggs and by injection of pyrimidine nucleosides. PMID- 4207298 TI - Ovulating-inducing activity of FSH in the rat. PMID- 4207299 TI - Sources and disposition of pituitary prolactin in maternal circulation, amniotic fluid, fetus and placenta in the pregnant rhesus monkey. PMID- 4207301 TI - Interaction between thymic hormone and hypophyseal growth hormone on production of precipitating antibodies in the rat. PMID- 4207300 TI - The pineal gland: a supplemental source of hypothalamic-releasing hormones. PMID- 4207302 TI - Transmission of kuru and Creutzfeldt-Jakob disease to marmoset monkeys. PMID- 4207303 TI - Imaging with radioactive microspheres to demonstrate maternal circulation in the placenta of rhesus monkeys. PMID- 4207305 TI - Ticarcillin, a new semisynthetic penicillin active on Pseudomonas aeruginosa: in vitro activity and blood levels in man. PMID- 4207304 TI - The effect of intraspinal masses on flow in the epidural venous system. PMID- 4207306 TI - Adhesion of Vi antigen and toxicity in typhoid vaccines inactivated by acetone or by heat and phenol. PMID- 4207307 TI - Immunological investigations of meningococcal disease. II. Some characteristics of group C antigen of Neisseria meningitidis in the sera of patients with fulminant meningococcemia. PMID- 4207309 TI - Epidemic disease due to serogroup C Neisseria meningitidis in Sao Paulo, Brazil. PMID- 4207308 TI - Course of experimental scrapie virus infection in the goat. PMID- 4207310 TI - Demonstration of Neisseria gonorrhoeae with fluorescent antibody in patients with disseminated gonococcal infection. PMID- 4207312 TI - Letter: Wound infection with Shigella flexneri. PMID- 4207311 TI - Vitamin A-induced nonspecific resistance to infection. PMID- 4207313 TI - Letter: Dopa oxidase bands. PMID- 4207314 TI - Blue-green algal proteins: assembly forms of C-phycocyanin from Synechococcus sp. PMID- 4207315 TI - Thyrotropin releasing hormone: enhancement of DOPA activity in thyroidectomized rats. PMID- 4207316 TI - Remote nerve fibre bundle alterations in the retina as caused by argon laser photocoagulation. PMID- 4207317 TI - Bioconvection patterns in swimming microorganism cultures as an example of Rayleigh-Taylor instability. PMID- 4207319 TI - Progress of a breeding project for non-human primates in Colombia. PMID- 4207318 TI - Decrease of polysomes in Tetrahymena after synchronisation shocks. PMID- 4207320 TI - Social hierarchy in monkeys (Macaca mulatta) modified by chlordiazepoxide hydrochloride. PMID- 4207321 TI - The use of immunoelectro-osmophoresis in the laboratory diagnosis of disseminated intravascular coagulation. PMID- 4207322 TI - The agar dilution method of testing the sensitivity of bacteria to antibiotics. PMID- 4207323 TI - Bacterial suspensions for the growth of Naegleria species. PMID- 4207324 TI - Estimating lecithin-sphingomyelin area ratio in amniotic fluid. A modified method for the prediction of neonatal respiratory distress. PMID- 4207325 TI - Aspects of experimental hepatocarcinogenesis. I. Early hyperplastic foci. PMID- 4207326 TI - Some aspects of epilepsy and convulsions in childhood. PMID- 4207327 TI - Radiolabeled chelates for visualization of kidney function and structure with emphasis on their use in renal insufficiency. PMID- 4207329 TI - [Dynamics in the cellulization of milk in cases of experimentally provoked subclinical mastitis]. PMID- 4207328 TI - [Obtaining homogeneous carboxypeptidase from Streptomyces griseus]. PMID- 4207330 TI - [Effect of the circadian rhythm of two milkings on the values of the NK-test in mastitis]. PMID- 4207331 TI - [Comparison of the effectiveness of a chlortetracycline-nitrofurantoin combination with that of single components in cases of diarrhea in newborn calves]. PMID- 4207332 TI - [Potentiation of sulfadimidine by trimethoprim in infectious diarrhea of calves]. PMID- 4207333 TI - [Effectiveness of the combination of neomycin with furazolidone and its individual components in gastroenteritides of newborn calves]. PMID- 4207334 TI - [Preventive effect of the combination of pepsin, rennet, acipepsol and kitchen salt administered to calves in cases of gastroenteritis]. PMID- 4207335 TI - [Effect of peroral and intramuscular administration of vitamin E on lipoperoxidation in the tissue of piglets]. PMID- 4207336 TI - [The activity of forms of glycogen synthetase dependent on and independent of glucose-6-phosphate in the brain under different functional conditions]. PMID- 4207337 TI - [Comparative studies in vitro on the antibiotic effectiveness of Terizidon]. PMID- 4207338 TI - Exploratory behavior and activity of infant monkeys during nutritional and rearing restriction. PMID- 4207339 TI - Nutritional vitamin B12 deficiency in rhesus monkeys. PMID- 4207340 TI - Evaluation of the nutritional quality of food supplies: prediction of "desirable" or "safe" protein: calorie ratios. PMID- 4207341 TI - Chromium nutrition in man. PMID- 4207342 TI - Studies on the antimalarial effects of RC-12 and WR 14,997 on the development of Plasmodium cynomolgi in mosquitoes and Rhesus monkeys. PMID- 4207343 TI - Schistosomiasis haematobia in African, hamadryas, and gelada baboons. PMID- 4207344 TI - [Myeloarchitecture of the mesencephalon in the domestic swine (Sus scrofa domestica)]. PMID- 4207345 TI - Latent radiation injury of lungs or heart activated by steroid withdrawal. PMID- 4207346 TI - Health and health services in the United States. A perspective and a discussion of some issues. PMID- 4207347 TI - Letter: Lingual thyroid. PMID- 4207348 TI - Letter: Psuedomonas septicemia and splenectomy. PMID- 4207349 TI - Improved management of esophageal perforation: exclusion and diversion in continuity. PMID- 4207350 TI - Small intestinal atresia: the critical role of a functioning anastomosis. PMID- 4207352 TI - Porcine aortic valves as replacements for human heart valves. PMID- 4207351 TI - Candida sepsis: pathogenesis and principles of treatments. PMID- 4207354 TI - [Studies on oxytetracycline tissue level in man following intravenous administration]. PMID- 4207355 TI - Mannosidosis: detection of the disease and of heterozygotes using serum and leucocytes. PMID- 4207353 TI - Pharmacological evaluation of 3-(N-3,3-diphenylpropyl-N-methyl)-aminopropan-1-ol hydrochloride (PF-82), a new type of antidepressant drug. PMID- 4207357 TI - Effects of the diastereoisomers of methylenetetrahydrofolate on the reaction catalyzed by thymidylate synthetase. PMID- 4207356 TI - Synthesis of diphtheria toxin in E. coli cell-free lysate. PMID- 4207358 TI - Phagocytic activity of macrophages from C57-Bl and CBA mice. PMID- 4207360 TI - Two Bence Jones proteins of different immunological type (light chains kappa and lambda) in a case of micromolecular myeloma. PMID- 4207359 TI - Values of the IgG, IgA, IgM immunoglobulins and of the fraction C'3 of the complement in 200 normal subjects. PMID- 4207361 TI - Conjugation in Tetrahymena: the relationship between the division cycle and cell pairing. PMID- 4207362 TI - Drosophilia myogenesis in vitro: the genesis of "small" myocytes and myotubes. PMID- 4207363 TI - Permeabilization of Drosophila eggs. PMID- 4207364 TI - Observations on lipolysis in ketosis-resistant, growth-onset diabetes. PMID- 4207365 TI - Assessors of fetal perinatal mortality in diabetic pregnancy. Analysis of 1,332 pregnancies in the Copenhagen series, 1946-1972. PMID- 4207366 TI - Homeostasis of body weight in a diabetes clinic population. PMID- 4207367 TI - Inhibition by somatostatin on the release of TSH induced in man by thyrotropin releasing factor. PMID- 4207368 TI - Effect of acute and long-standing hypocalcemia on blood pressure and plasma renin activity in man. PMID- 4207369 TI - Thermal inactivation of thyroxine-binding globulin for direct radioimmunoassay of triiodothyronine in serum. PMID- 4207370 TI - Failure of somatostatin to suppress thyrotropin releasing factor and luteinizing hormone releasing factor-induced growth hormone release in acromegaly. PMID- 4207371 TI - Maternal dietary deficiency and cellular development of progeny in the rat. PMID- 4207372 TI - Radiation therapy of inoperable localized prostate carcinoma: an assessment of tumor response and complications. PMID- 4207373 TI - Thydrotropin releasing hormone: antagonism of pentobarbital in rodents. PMID- 4207374 TI - Effect of carbonic anhydrase inhibition on shell penetration by the muricid gastropod Urosalpinx cinerea. PMID- 4207375 TI - Thyrotropin-releasing hormone is not the sole physiologic mediator of prolactin release during suckling. PMID- 4207376 TI - Editorial: Control of prolactin in man. PMID- 4207377 TI - Letter: Quantitation of nerve-growth-stimulating activity. PMID- 4207378 TI - Gene dosage compensation in metafemales (3X;2A) of Drosophila. PMID- 4207379 TI - Non-specific "pairing" of DNA molecules by recombination enzyme of Bacillus subtilis. PMID- 4207380 TI - [Chlorinated hydrocarbons in the human fat]. PMID- 4207381 TI - Pulmonary embolism complicating permanent cardiac pacing. PMID- 4207382 TI - Letter: Heterotopic bone formation in abdominal scars. PMID- 4207383 TI - The significance of epileptic seizures in infancy and childhood. PMID- 4207384 TI - [Serological activity of the components of the elastolytic complex of Actinomyces rimosus]. PMID- 4207385 TI - Acute pressure changes and possible secondary tissue changes due to laser or xenon photocoagulation. PMID- 4207386 TI - A low-molecular-weight protein cross-reacting with human liver N-acetyl-beta-D glucosaminidase. AB - Antisera were raised to preparations of hexosaminidase isoenzymes A and B purified from human liver. Protein that cross-reacted with the liver hexosaminidase was detected by an antibody-consumption method. A cross-reacting protein with a low molecular weight (20000) was partially characterized and purified from control human liver. This protein is also present in the liver of patients with Tay-Sachs disease or with Sandhoff's disease. Hexosaminidases A and B gave an immunological reaction of partial identity with the low-molecular weight protein. The possible identity of the low-molecular-weight cross-reacting protein as a subunit of hexosaminidase is discussed. PMID- 4207387 TI - Mannosidosis in Angus cattle. The enzymic defect. AB - Normal calf alpha-mannosidase activity exists in at least three forms separable by chromatography on DEAE-cellulose and by starch-gel electrophoresis. Two components, A and B, have optimum activity between pH3.75 and 4.75, but component C has an optimum of pH6.6. Components A and B are virtually absent from the tissues of a calf with mannosidosis and the residual activity is due to component C. The acidic and neutral forms of alpha-mannosidase differ in their molecular weights and sensitivity to EDTA, Zn(2+), Co(2+) and Mn(2+). An acidic alpha mannosidase component (pH optimum 4.0) accounts for most of the activity in normal plasma but it is absent from the plasma of a calf with mannosidosis. Although the acidic alpha-mannosidase component is probably related to tissue components A and B, it can be distinguished from them by ion-exchange chromatography and gel filtration. The optimum pH of the low residual activity in the plasma from a calf with mannosidosis is pH5.5-5.75. The results support the hypothesis that Angus-cattle mannosidosis is a storage disease caused by a deficiency of lysosomal acidic alpha-mannosidase activity. PMID- 4207389 TI - Dihydrofolate reductase: low-resolution mass-spectrometric analysis of an elastase digest as a sequencing tool. AB - An elastase digest of a protein of unknown structure, dihydrofolate reductase, was studied by mass spectrometry. This soluble digest contained a large number of small peptides in different yields, within the ideal molecular-weight range (200 1200) for mixture-analysis mass spectrometry. Sequences of the major component peptides in the digest are reported. PMID- 4207388 TI - Cathepsin B1. A lysosomal enzyme that degrades native collagen. AB - 1. Experiments were made to determine whether the purified lysosomal proteinases, cathepsins B1 and D, degrade acid-soluble collagen in solution, reconstituted collagen fibrils, insoluble collagen or gelatin. 2. At acid pH values cathepsin B1 released (14)C-labelled peptides from collagen fibrils reconstituted at neutral pH from soluble collagen. The purified enzyme required activation by cysteine and EDTA and was inhibited by 4-chloromercuribenzoate, by the chloromethyl ketones derived from tosyl-lysine and acetyltetra-alanine and by human alpha(2)-macroglobulin. 3. Cathepsin B1 degraded collagen in solution, the pH optimum being pH4.5-5.0. The initial action was cleavage of the non-helical region containing the cross-link; this was seen as a decrease in viscosity with no change in optical rotation. The enzyme also attacked the helical region of collagen by a mechanism different from that of mammalian neutral collagenase. No discrete intermediate products of a specific size were observed in segment-long spacing crystalloids (measured as native collagen molecules aligned with N termini together along the long axis) or as separate peaks on gel filtration chromatography. This suggests that once an alpha-chain was attacked it was rapidly degraded to low-molecular-weight peptides. 4. Cathepsin B1 degraded insoluble collagen with a pH optimum below 4; this value is lower than that found for the soluble substrate, and a possible explanation is given. 5. The lysosomal carboxyl proteinase, cathepsin D, had no action on collagen or gelatin at pH3.0. Neither cathepsin B1 nor D cleaved Pz-Pro-Leu-Gly-Pro-d-Arg. 6. Cathepsin B1 activity was shown to be essential for the degradation of collagen by lysosomal extracts. 7. Cathepsin B1 may provide an alternative route for collagen breakdown in physiological and pathological situations. PMID- 4207390 TI - Mild and efficient solubilization of Escherichia coli cells for the analysis of chromosomal DNA by sucrose gradient centrifugation. PMID- 4207391 TI - Proceedings: An oxygen electrode for cranial implantation. PMID- 4207393 TI - [Chronic sputum-positive tuberculosis in the Poznan Province in the years 1969 1972]. PMID- 4207392 TI - Relation between zinc and iron and peroxidation of lipids in liver homogenate in CaEDTA-treated rats. PMID- 4207394 TI - Liquid formula and chemically defined diets. PMID- 4207395 TI - The effects of thrombin on phytohemagglutinin receptor sites in human platelets. AB - We have previously demonstrated that lentil phytohemagglutinin (lentil-PHA) binds to human platelet membranes without causing either aggregation or the release reaction. When platelets are treated with thrombin, there is an increase in lentil-PHA binding suggesting the appearance of new receptor sites on the cell surface. We prepared a lentil-PHA-ferritin conjugate using affinity chromatography which was used to saturate cell surface receptor sites. Studies using this conjugate suggest that thrombin causes a complex change in the platelet surface involving a decrease in the number of lentil-PHA receptor sites on the external platelet surface with a marked increase in sites within the center of the canalicular system. These increased sites may result from fusion of granule membranes with the canalicular membranes during the secretion process. There is no obvious relationship between lentil-PHA receptor sites and intramembranous particles. PMID- 4207396 TI - Effects of serum on membrane transport. II. Serum and the stimulation of adenosine transport, a possible mechanism. AB - When monolayers of freshly obtained rabbit lung macrophages are exposed to the nucleoside analogue, showdomycin (sho), adenosine transport, measured over a 45 s interval, is irreversibly inhibited. Low doses of the drug or short periods of exposure, however, do not result in decreased transport, while higher concentrations or longer exposures result in exponential decline. The initial lag is not due to a long reaction time of sho with the transport carrier or to nonspecific sites absorbing the drug. Previously it was shown that preincubation of monolayers with normal rabbit serum (NRS) results in increased adenosine transport. When monolayers are first exposed to sho so as to inhibit transport to varying degrees and then incubated with NRS, transport is increased over the inhibited level. Several experiments make it unlikely that serum removes the drug from the cell surface in a nonspecific fashion. Moreover, serum given before, during, or after sho alters the dose response curve so that no shoulder is seen. One way to explain these results makes use of target theory: the adenosine transport system could be comprised mainly of "coupled" or "clustered" sites of which only one is active at any time as well as "hidden" sites which are inactive. When a site in a group is irreversibly inactivated by sho, another in the group becomes activated. Serum might activate or uncouple all sites and also cause the appearance of hidden sites, which previously neither transported nor bound sho. PMID- 4207397 TI - Mitochondrial and cytoplasmic ribosomes from Tetrahymena pyriformis. Correlative analysis by gel electrophoresis and electron microscopy. AB - Mitochondrial and cytoplasmic ribosomes from Tetrahymena pyriformis have been isolated and studied by the techniques of polyacrylamide gel electrophoresis and electron microscopy used in conjunction. Although the two ribosome types show the same coefficient of sedimentation (80S) in sucrose gradients, they can be distinguished by gel electrophoresis: mitoribosomes migrate in a single band, considerably slower than the cytoribosome band. Electron microscope observations of negatively stained cytoribosomes show typical rounded or triangular profiles, about 275 x 230 A; mitoribosome profiles are much larger and clearly elongate, about 370 x 240 A. An electron-opaque spot delimits two nearly equal size subunits. In mixtures of mito- and cytoribosomes, each type can be recognized by its characteristic electrophoretic mobility and by its distinctive fine structure. Cytoribosomal 60S and 40S subunits each produce a distinct electrophoretic band. On the contrary, neither electrophoretic analysis, using a variety of conditions, nor electron microscopy is able to discern two different subunit types in the single 55S mitoribosomal subunit peak. Electrophoretic analysis of RNA shows that both ribosomal RNA species are present in the mitoribosomal subunit fraction. These results establish that mitoribosomes from T. pyriformis dissociate into two subunits endowed with the same sedimentation coefficient, the same electrophoretic mobility, and a similar morphology. PMID- 4207398 TI - Membrane junctions in the intermembrane space of mitochondria from mammalian tissues. AB - There have been several reports describing paracrystalline arrays in the intermembrane space of mitochondria. On closer inspection these structures appear to be junctions of two adjoining membranes. There are two types. They can be formed between the outer and inner mitochondrial membranes (designated outer inner membrane junctions) or between two cristal membranes (intercristal membrane junctions). In rat heart, adjoining membranes appeared associated via a central dense midline approximately 30 A wide. In rat kidney, the junction had a ladder like appearance with electron-dense "bridges" approximately 80 A wide, spaced 130 A apart, connecting the adjoining membranes. We have investigated the conditions which favor the visualization of such structures in mitochondria. Heart mitochondria isolated rapidly from fresh tissue (within 30 min of death) contain membrane junctions in approximately 10-15% of the cross sections. This would indicate that the percentage of membrane junctions in the entire mitochondrion is far greater. Mitochondria isolated from heart tissue which was stored for 1 h at 0 degrees -4 degrees C showed an increased number of membrane junctions, so that 80% of the mitochondrial cross sections show membrane junctions. No membrane junctions are observed in mitochondria in rapidly fixed fresh tissue or in mitochondria isolated from tissue disrupted in fixative. Thus, the visualization of junctions in the intermembrane space of mitochondria appears to be dependent upon the storage of tissue after death. Membrane junctions can also be observed in mitochondria from other stored tissues such as skeletal muscle, kidney, and interstitial cells from large and small intestine. In each case, no such junctions are observed in these tissues when they are fixed immediately after removal from the animal. It would appear that most studies in the literature in which isolated mitochondria from tissues such as heart or kidney were used were carried out on mitochondria which contained membrane junctions. The presence of such structures does not significantly affect normal mitochondrial function in terms of respiratory control and oxidative phosphorylation. PMID- 4207399 TI - Radium uptake by fresh water algae. PMID- 4207400 TI - [Disinfection dispositions in the DDR within the system of the antimicrobial regimen]. PMID- 4207402 TI - Homogeneity of Rickettsia prowazeki E strain egg culture as to the capacity to increase virulence in passages on white mouse lungs. PMID- 4207401 TI - Contribution to knowledge of factors participating in virulence of Listeria monocytogenes. I. Isolation and properties of the biologically active complex E. PMID- 4207403 TI - The need for field-laboratory facilities for primate research. PMID- 4207405 TI - Two distinctive types of owl monkeys (Aotus). PMID- 4207404 TI - The sensitive period and malformation syndrome produced by thalidomide in crab eating monkey (Macaca fascicularis). PMID- 4207406 TI - The ABO blood groups in vervet monkeys (Cercopithecus pygerythrus F. Cuvier). PMID- 4207407 TI - Vascular heterograft: human umbilical cord vein as an aortic substitute in baboon. A preliminary report. PMID- 4207408 TI - Comparison of two early separation and weaning schedules of infant rhesus monkeys (Macaca mulatta). PMID- 4207409 TI - Lymphocyte transformation induced by culture media supplemented with primate serum. PMID- 4207410 TI - Single toxic doses of 131-I: administration to Macaca mulatta. Preliminary report. PMID- 4207411 TI - Depression of polymorph counts by various scrapie agents. PMID- 4207413 TI - Mechanisms for control of neural activity of the cerebral association cortex. I. The occurrence of augmenting potentials in the frontal granular cortex during stimulations of the nucleus medialis dorsalis. PMID- 4207414 TI - Mechanisms for control of neural activity of the cerebral association cortex. II. The occurrence of recruiting type of potentials in the frontal granular cortex during stimulations of medial thalamus. PMID- 4207412 TI - Enhancement of cerebral noradrenaline turnover by thyrotropin-releasing hormone. PMID- 4207415 TI - [Epileptic seizures in infantile cerebral palsy]. PMID- 4207416 TI - [Epidemiology of epilepsy in the population of a large industrial town. Incidence and morbidity]. PMID- 4207417 TI - [A case of the Moebius syndrome with symptoms similar to the 18 p- syndrome, but with normal karyotype]. PMID- 4207418 TI - [Epileptic manifestations in cerebral vascular accidents]. PMID- 4207419 TI - [Therapeutic plan for nonobstructive urinary tract infections. Short communication]. PMID- 4207420 TI - Post-prandial EEG synchronization in normal and hypothalamically lesioned rats. PMID- 4207421 TI - Operant discrimination of interoceptive urinary bladder stimulation in the monkey. PMID- 4207422 TI - Interocular reversal of up-down mirror images in pigeons. PMID- 4207423 TI - Producing and interpreting experimental olfactory deficits. PMID- 4207424 TI - Sleep induced by hypothalamic self-stimulation in cat. PMID- 4207426 TI - [Variations and abnormalities of the caudal sac]. PMID- 4207425 TI - Cardiac involvement in inherited disorders of metabolism. PMID- 4207427 TI - [Hay fever as a delayed hypersensitivity reaction]. PMID- 4207428 TI - [Comment on the paper by J. Klingeberg: Mechanical irrigation of the bladder using the "Vesicomat" (this J. 12, 148-150 (1973))]. PMID- 4207429 TI - [Final comment on the paper: Mechanical irrigation of the bladder using the "Vesicomat" (this J. 12, 148-150) 1973]. PMID- 4207430 TI - [Parenteral feeding]. PMID- 4207431 TI - [The immune peroxidase method for demonstration of viral and chlamydia antigens. 3. Demonstration of TGE-virus antigen in porcine thyroid gland cell cultures]. PMID- 4207432 TI - [Bovine mastitis due to Bacillus cereus. II. Antibiogram and pathogenicity tests of the isolated strain]. PMID- 4207433 TI - [Suppurating neurofibroma of the left parotid region in Recklinghausen's disease]. PMID- 4207434 TI - Polymers in medicine. PMID- 4207436 TI - Cis-trans-isomerism of thyrotropin releasing hormone (TRH) in aqueous solution. PMID- 4207437 TI - [Electrosyneresis used in the diagnosis of aspergillosis and bronchopulmonary aspergilloma. Comparative study with other technics of immunoprecipitation and with immunofluorescence]. PMID- 4207435 TI - Biopolymers: origin, chemistry, and biology. PMID- 4207438 TI - [Urinary tract infections in patients hospitalized in a department of internal medicine. Bacteriological and clinical studies and therapeutic results in 925 cases]. PMID- 4207440 TI - [Fatal myocardial tears in acute infarction]. PMID- 4207439 TI - Food poisoning due to Vibrio parahaemolyticus. PMID- 4207441 TI - [Treatment of the acute phase of myocardial infarct using constant monitoring in an intensive care unit]. PMID- 4207443 TI - [Professional rehabilitation of heart surgery patients]. PMID- 4207442 TI - [Prediction of the duration of ejection and systolic ejection volume in subjects with normal left ventricles and in various cardiopathies]. PMID- 4207444 TI - [Comparative studies of the effects of left and right atrial stimulation in Wolff Parkinson-White syndrome]. PMID- 4207446 TI - [Pure pulmonary artery sequestration and continous murmur]. PMID- 4207447 TI - [Immediate and long-term results of the complete correction of transposition of great vessels in the child]. PMID- 4207445 TI - [Value and limits of bundle of His exploration in the study of apparent ventricular tachycardias]. PMID- 4207449 TI - [Aortopulmonary fistulas (study of 10 surgical cases)]. PMID- 4207448 TI - [Right atrial and ventricular diastolic phase in adiastole]. PMID- 4207450 TI - [Immediate and mid-term results of aortic valve replacement by a ball prothesis in subjects more than 60 years old. (Apropos of 43 cases)]. PMID- 4207452 TI - [Course and late complications after insertion of an aortic Starr valve]. PMID- 4207451 TI - [Aortic orifice surgery after 60 years of age]. PMID- 4207453 TI - [Delayed second operation for vascular prosthesis]. PMID- 4207454 TI - [Role of walking in the rehabilitation of coronary patients]. PMID- 4207455 TI - [Biochemical and anatomopathological aspects of the myocardium of different species of animals ingesting colza oil]. PMID- 4207456 TI - [Fibrous endocarditis of the left ventricle in a patient with filariasis; surgical cure]. PMID- 4207457 TI - [Chronic heart failure due to ischemic cardiopathy and and aortocoronary bypasses: study of the operative results in 11 patients]. PMID- 4207458 TI - [Postoperative pulmonary insufficiency. Long-term course (tetralogy of Fallot excluded)]. PMID- 4207460 TI - [Acute respiratory insufficiency and myocardial infarct. Ventilatory assistance in the treatment of myocardial necrosis]. PMID- 4207459 TI - [Correlation between angiography and peroperative or histological anatomical data in left ventricluar aneurysms (apropos of 31 consecutive patients)]. PMID- 4207461 TI - [False mitral stenosis in apparent primary myocardiopathy]. PMID- 4207462 TI - [Long-term uncomplicated junctional tachycardia (apropos of 3 cases)]. PMID- 4207463 TI - [Initial QRS vector in intraventricular conduction disorders]. PMID- 4207464 TI - [Complete right bundle-branch and bifascicular blocks during the acute phase of myocardial infarction]. PMID- 4207466 TI - [Candida endocarditis in mitral prosthesis (apropos of a case cured by a second operation)]. PMID- 4207465 TI - [Natural history of coronary atherosclerosis in Iranian workers]. PMID- 4207467 TI - [Isolated complete right bundle-branch block in a young patient, caused by atresia of the first third of the right branch (study of an anatomoclinical case)]. PMID- 4207468 TI - [Evolution of coronary blood flow in the course of myocardial infarction]. PMID- 4207470 TI - [Mitral commisurotomy in subjects more than 60 years old]. PMID- 4207469 TI - [Ajmaline test in the diagnosis of paroxysmal atrioventricular block]. PMID- 4207471 TI - [Peri-infarction blocks and segmentary blocks]. PMID- 4207472 TI - [Splenic rupture in the course of infectious endocarditis (apropos of 3 new cases]. PMID- 4207473 TI - [Midterm results of Carpentier's reconstructive mitral annuloplasty]. PMID- 4207474 TI - [Apexo-carotid diagram]. PMID- 4207475 TI - [Coronary angina and stimulation of carotid sinus nerves. Long-term results]. PMID- 4207476 TI - [Comparison of the effects of disopyramide and hydroquinidine in animals]. PMID- 4207477 TI - [Congenital heart diseases in the Senegalese (apropos of 151 patients in Dakar)]. PMID- 4207478 TI - [Value of the maxiaml effort test and of auricular pacing for the diagnosis of coronary insufficiency]. PMID- 4207479 TI - [Raymond Heim de Balsac (1903-1972)]. PMID- 4207480 TI - [Recording His bundle activity in AV blocks in children]. PMID- 4207481 TI - [Results of tricuspid surgery. Apropos of 65 surgical patients]. PMID- 4207482 TI - [Calcified aortic stenosis and coronary atherosclerosis]. PMID- 4207483 TI - [Principles of exploration of dissecting aortic aneurysms by arterial catheterization; value of radiocinema]. PMID- 4207484 TI - [Use of valved tubes in the complete correction of certain congenital cardiopathies (truncus, great vessel transposition)]. PMID- 4207485 TI - [Angiocardiographic aspects of the single ventricle]. PMID- 4207486 TI - [Syncope by volley of ventricular spikes induced or encouraged by prenylamine]. PMID- 4207487 TI - [Ventricular fibrillation at the acute phase of myocardial infarction: prognosis after resuscitation]. PMID- 4207488 TI - [Inhibition of a sentinel pacemaker by very weak thoracic skin currents and study of the underlying electrocardiogram]. PMID- 4207489 TI - [Risks in connection with pregnancy and delivery in women fitted with pacemakers (apropos of a case)]. PMID- 4207490 TI - Immunological studies on human salivary albumin. PMID- 4207491 TI - Effect of anti-cell and anti-axial filament sera on Leptospira. PMID- 4207492 TI - The reaction of near-isogenic lines of flax to the rust fungus Melampsora lini. II. Biochemical studies. PMID- 4207494 TI - The relative quantities and catalytic activities of enzymes produced by alleles at the alcohol dehydrogenase locus in Drosophila melanogaster. PMID- 4207493 TI - Properties of genetically polymorphic isozymes of alcohol dehydrogenase in Drosophila melanogaster. PMID- 4207495 TI - Alkaline phosphatase of Drosophila melanogaster. 3. Tyrosine-O-phosphate as substrate. PMID- 4207496 TI - Pteridine diuretics as biopterin antagonists. PMID- 4207497 TI - Preparation of human kininogen. 3. Enzymatic digestion and modification. PMID- 4207498 TI - Effects of the mycotoxin sporidesmin on swelling and respiration of liver mitochondria. PMID- 4207501 TI - [Long-term parenteral feeding with hypertonic solutions]. PMID- 4207499 TI - The involvement of the disulphide group of sporidesmin in the action of the toxin on swelling and respiration of liver mitochondria. PMID- 4207500 TI - Lymphographic appearances in Waldenstrom's macroglobulinaemia. PMID- 4207502 TI - Eosinophillic granuloma of the lung with sawdust and horse protein hypersensitivity. PMID- 4207503 TI - Farmer's lung following inhalation of Aspergillus flavus growing in mouldy corn. PMID- 4207504 TI - Experimental extrinsic allergic alveolitis induced in the guinea-pig with Streptomyces olivaceus. PMID- 4207505 TI - [Therapy of angina pectoris. II. Evaluation of antianginous drugs. Nitrites and nitrates]. PMID- 4207506 TI - Persistent scabious nodules. PMID- 4207507 TI - [Comprehensive review: sporogony and resistence of oocysts]. PMID- 4207508 TI - [The occurrence of carbonic anhydrase in the hen's egg shell]. PMID- 4207510 TI - [The effect of several substances of the phenothiazine series and alpha adrenoblockers on spinal cord activity with inhibitory mechanisms disrupted by tetanus toxin]. PMID- 4207509 TI - Mutagenicity experiments with the tranquillizer meprobamate in Drosophila melanogaster and in human leukocyte chromosomes in vitro. PMID- 4207512 TI - [Vitamin (B-1 and B2) balance and the antitoxic function of the liver under conditions of experimental thiophosphamide therapy]. PMID- 4207511 TI - [Changes in the circulation and oxygen regimen of the brain while using coronary dilating drugs]. PMID- 4207513 TI - Existence of two distinct hemolysins in Vibrio parahaemolyticus. AB - Two distinct hemolysins were demonstrated in Vibrio parahaemolyticus. A thermostable direct hemolysin purified from V. parahemolyticus WP-1, a Kanagawa phenomenon (KP)-positive strain, is antigenically different from a thermolabile hemolysin produced by V. parahaemolyticus T-3454, a KP-negative strain. The thermostable direct hemolysin was found in KP-positive strains but not in KP negative strains. On the other hand, the thermolabile hemolysins were found in both KP-positive and -negative strains, although some KP-positive strains did not produce this hemolysin. PMID- 4207514 TI - Assessment of germ tube dispersion activity of serum from experimental candidiasis: a new procedure for serodiagnosis. AB - Germ tubes of Candida albicans and C. stellatoidea clump in normal serum but disperse in serum from animals infected with either species of Candida. A new procedure for the assessment of grades of germ tube dispersion activity of serum is presented; this procedure is to count the number of freely dispersed germ tubes in test serum into which a definite number of yeast-type C. albicans has been inoculated. The relationship between the serum activity and macroscopic lesions caused by candidal infection is observed, indicating the possibility of applying the phenomenon to the serodiagnosis of deep-seated candidiasis. The specificity and sensitivity of the test are also examined. PMID- 4207515 TI - Enhanced in vitro phagocytosis of Listeria monocytogenes by human monocytes in the presence of ampicillin, tetracycline, and chloramphenicol. AB - An in vitro system was developed to test the phagocytic activity of human macrophages grown from blood monocytes in the presence of the antibiotics ampicillin, tetracycline, and chloramphenicol. (3)H-labeled Listeria monocytogenes served as test organism. Subinhibitory amounts of the antibiotics enhanced the phagocytic activity significantly (P < 0.025). Macrophages pretreated with the drugs in identical concentrations showed the same phagocytic activity as control cells in the absence of the drugs. Because the drug concentrations used were similar to those that may be attained in man at certain places of inflammation, enhanced phagocytosis in the presence of antibiotics may have clinical significance. PMID- 4207516 TI - Serological and cellular immune activity of peptidoglucomannan fractions of Candida albicans cell walls. AB - A two-stage extraction of isolated cell walls of C. albicans resulted in 45% solubilization into antigens of high molecular weight leaving a wall residue which also had antigenic properties. Ice-cold dilute alkali removed 25% of the defatted cell walls. The extract was nondialyzable, had a glucose-to-mannose ratio of 2:3 and an amino acid content of 7.32%, and was designated peptidoglucomannan (PGM). An additional 26% of the walls resistant to stage I were solubilized by sonic treatment yielding a fraction having a glucose-to mannose ratio of 6:1, termed soluble mannoglucan (sMG). The residue after extraction and sonic treatment contained 10.9% mannose, which was the insoluble mannoglucan. The gel permeation behavior of PGM and sMG on BioGel A5M was similar; each contained two components, one estimated to exceed 5 x 10(6) molecular weight and a second smaller species. The soluble cell wall fractions were active in immunodiffusion and carried antigenic group specificity. Immunoelectrophoresis of PGM, sMG, and mannan revealed some heterogeneity. The insoluble mannoglucan had agglutinating activity. A distinctive immunodiffusion pattern of cell wall antigens was formed with the serum of a leukemic patient with candidiasis. All three cell wall antigens and mannan elicited delayed-type hypersensitivity as measured by skin-test and specific inhibition of macrophage migration. A dose of 25 mug of PGM was sufficient to inhibit 89.9% migration in the peritoneal exudates of guinea pigs immunized with cell walls, and 10 mug of PGM inhibited 91.7% migration in guinea pigs immunized with insoluble mannoglucan. PMID- 4207517 TI - Differential attachment by piliated and nonpiliated Neisseria gonorrhoeae to human sperm. AB - Piliated type 1 Neisseria gonorrhoeae attached to 50% of human sperm after incubation of mixtures in vitro for 15 min at 35 C. In contrast, nonpiliated type 4 N. gonorrhoeae attached to only 23% of sperm. Similar results were obtained with three different strains of N. gonorrhoeae. Treatment with heat or formaldehyde to kill bacteria did not affect the amount of attachment by piliated or nonpiliated types. Escherichia coli and N. subflava, other species of piliated bacteria, attached to about 40% of sperm, and the nonpiliated species N. meningitidis and N. catarrhalis attached to a comparable number of sperm, as did type 4 N. gonorrhoeae. Prior incubation of type 1 N. gonorrhoeae with purified antibody prepared against gonococcal pili reduced the percentage of sperm with attached bacteria to the same level as that for nonpiliated type 4 gonococci. Similar treatment of other piliated organisms or of nonpiliated Neisseria did not affect the attachment of the bacteria to sperm. PMID- 4207518 TI - BCG antibody profiles in tuberculoid and lepromatous leprosy. AB - In sera from 12 patients with polar tuberculoid leprosy, 12 with subpolar tuberculoid leprosy, and 16 with lepromatous leprosy were demonstrated a total number of 125 anti-BCG precipitins by means of crossed immunoelectrophoresis with intermediate gel. Up to 14 different precipitins were found in individual sera, and the complexity in antibody response was higher than previously realized. The specificity of 69% of the antibodies was defined, and these antibodies were titrated in three arbitrary titer units. A highly significant difference (P < 0.002) was found in antibody response between the tuberculoid and the lepromatous group. Due to simplicity, sensitivity, and high resolution, the method used is a promising tool for providing exact data to be used as guidelines for purification of important individual mycobacterial antigens. The need for reference antisera is emphasized. PMID- 4207519 TI - Viability of L-phase variants after centrifugation. AB - L-phase variants of several genera may be centrifuged with minimal, if any, loss of viability. PMID- 4207520 TI - Rickettsial infectious antibody complexes: detection by antiglobulin plaque reduction technique. AB - Rickettsia rickettsii and R. australis formed infectious antibody complexes when reacted with homologous convalescent serum. The addition of antiglobulin to these complexes showed neutralization of plaques proportional to the concentration of rickettsial immune serum. PMID- 4207521 TI - Carbuncle: discussion and a report of two cases. PMID- 4207522 TI - Conization operation using an automated cutting device. PMID- 4207523 TI - The treatment of pharyngeal pouch. PMID- 4207524 TI - [Cortical and intracortical study of the frontal potential visually evoked in photosensitive Papio papio]. PMID- 4207525 TI - The role of zinc in promoting the opalescence and cold precipitation of boar seminal plasma. II. Relationship of a zinc-precipitable protein with the haemagglutinin. PMID- 4207526 TI - Host DNA synthesis-suppressing factor in culture fluid of tissue cultures infected with measles virus. AB - Host DNA synthesis is suppressed by the culture fluid of cell cultures infected with measles virus. This activity in the culture fluid is initiated somewhat later than the growth of infectious virus. Ninety percent of host DNA synthesis in HeLa cells is inhibited by culture fluid of 3-day-old cell cultures of Vero or HeLa cells infected with measles virus. This suppressing activity is not a property of the virion, but is due to nonvirion-associated component which shows none of the activities of measles virus such as hemagglutination, hemolysis, or cell fusion nor does it have the antigenicity of measles virus as tested by complement-fixation or hemagglutination-inhibiting antibody blocking tests. Neutralization of the activity of this component is not attained with the pooled sera of convalescent measles patients. This component has molecular weights of about 45,000, 20,000, and 3,000 and appears to be a heat-stable protein. The production of host DNA suppressing factor (DSF) is blocked by cycloheximide. Neither UV-inactivated nor antiserum-neutralized measles virus produce DSF. Furthermore, such activity of nonvirion-associated component is not detected in the culture fluid of cultures infected with other RNA viruses such as poliovirus, vesicular stomatitis virus, or Sindbis virus. PMID- 4207527 TI - Scrapie and transmissible mink encephalopathy: search for infectious nucleic acid. AB - Brain preparations from animals with scrapie or transmissible mink encephalopathy were phenol extracted and examined for the presence of pathogenic nucleic acid. Animals inoculated with various extracts remained healthy, and analysis on 2.6 to 5% polyacrylamide gels failed to detect a difference in extractable RNA species between infected and normal mink brain. PMID- 4207528 TI - The action of rubiflavin and other cytostatic antibiotics on Euglena gracilis. PMID- 4207529 TI - Chromosomal characteristics of a lymphoblastoid line from baboon Chacma Papio papio: similarity to human lymphoblastoid lines. PMID- 4207530 TI - Physical and chemical abnormalities in a series of 155 paraproteinemic sera of the main immunoglobulin classes. PMID- 4207531 TI - Effects of ephemeral fever on milk production and reproduction of dairy cattle. PMID- 4207532 TI - Tracheobronchial anomalies in children. PMID- 4207533 TI - Intrauterine rubella infection. PMID- 4207534 TI - Agammaglobulinemia associated with Australia-antigen-positive chronic active hepatitis. PMID- 4207535 TI - [The relationship between the amino acid composition of hydrogen bacteria and the condition of their mineral nutrition]. PMID- 4207536 TI - [The antibacterial activity of several quaternary ammonium compounds]. PMID- 4207537 TI - [The effect of ultraviolet rays on the microflora of meat]. PMID- 4207538 TI - [The concentration of inclusion endotoxin in cultures of entomopathogenic crystal forming bacilli]. PMID- 4207540 TI - Significance of arterial lesions in the comparative pathology of spontaneous atherosclerosis. PMID- 4207539 TI - [Chronic hepatitis. New classification and clinical criteria]. PMID- 4207541 TI - Accuracy and precision in measurement of human serum immunoglobulins G, A and M. PMID- 4207542 TI - Presence in dental plaque of a polysaccharide antigen of the anaerobic oral filamentous organism Eubacterium saburreum. PMID- 4207543 TI - Fibrosarcoma with metastasis in a rhesus monkey. PMID- 4207544 TI - Experimental studies on the formation of epithelioid cells induced by fractionated substances of tubercle vacilli. PMID- 4207545 TI - Immunochemical properties of rabbit antibodies in membranous glomerulonephritis. PMID- 4207546 TI - Electron microscopical study on the tumor of von Recklinghausen's neurofibromatosis. PMID- 4207547 TI - On non-specific inhibition of rat liver microsomal UDP glucuronyltransferase by some drugs. PMID- 4207549 TI - [To be alive costs nothing]. PMID- 4207554 TI - Pulpal response to a new composite dental restorative material. PMID- 4207548 TI - Epoxide hydrase in human liver biopsy specimens: assay and properties. PMID- 4207555 TI - [Proceedings: 31. The effect of stimulator and inhibitors of protein synthesis on the response of the toad's urinary bladder to vasopressin (author's transl)]. PMID- 4207556 TI - Proceedings: 122. Comparison of thermoregulatory responses in the Japanese monkey(Macaca fuscata) and the crab-eating monkey (Macaca irus) during cold exposure. PMID- 4207557 TI - [Proceedings: 195. Ca++ and Na+ on the inhibitory action of prostaglandin (PG) E in circular muscles from guinea pig stomach and dog intestine (author's transl)]. PMID- 4207559 TI - [Rational usage of orally administrated nitroglycerin in angina pectoris]. PMID- 4207560 TI - [Lactic acid acidosis and biguanides--a review]. PMID- 4207561 TI - [Biguanides and lactic acid acidosis]. PMID- 4207563 TI - Absence of nucleic acid in proteocin, a defective phage of Proteus mirabilis D52. PMID- 4207562 TI - ATP-dependent deoxyribonuclease from normal and rec-mutant strains of Bacillus subtilis. PMID- 4207564 TI - [Use of biolactin in the diet of young children with dysentery]. PMID- 4207565 TI - [Colpocytological determination of the hormonal function of the placenta in pregnant women with Rh-negative blood]. PMID- 4207566 TI - [Proceedings: Modifications of UDP-glucuronyltransferase enzyme and bilirubin metabolism in rats operated on by portacaval shunt and treated or not treated with sodium phenobarbital]. PMID- 4207567 TI - [Proceedings: Behavior of glucuronyl-transferase and beta-glucuronidase in the gastrointestinal and kidney mucosa in Wistar and Gunn rats]. PMID- 4207568 TI - [Proceedings: Effect of repeated administration of spironolactone, ethanol and phenobarbital on liver bilirubin UDPG-transferase in Gilbert's jaundice]. PMID- 4207569 TI - Proceedings: Lysosomal enzymes in lymphocytes. PMID- 4207570 TI - The repair of ultraviolet-damaged DNA in Bacillus subtilis. PMID- 4207571 TI - Leucocytes and thrombosis. II. Relationship between leucocyte behaviour and divalent cations, sulphydryl groups, red cells and adenosine diphosphate. PMID- 4207572 TI - Involvement of small mammals in the transmission of scrub typhus in Malaysia: isolation and serological evidence. PMID- 4207573 TI - Toxoplasmosis in free-ranging chacma baboons (Papio ursinus) from the Kruger National Park. PMID- 4207574 TI - Effects of immunosuppressive agents on the course of Trypanosoma (trypanozoon) brucei infections in heat-stressed mice. PMID- 4207575 TI - Exercise electrocardiography: recognition of the ischemic response, false positive and negative patterns. PMID- 4207577 TI - Myocardial infarction after exercise-induced electrocardiographic changes in a patient with variant angina pectoris. PMID- 4207576 TI - Effects of perhexiline on symptomatic and hemodynamic responses to exercise in patients with angina pectoris. PMID- 4207578 TI - Digesta passage and water exchange in the equine large intestine. PMID- 4207579 TI - Ventricular contractility during controlled exercise and emotion in the primate. PMID- 4207580 TI - Radioimmunoassay on polycarbonate membranes: a sensitive and simplified method for the detection and quantitation of antibody. AB - A new radioimmunoassay technique is described in which a sampling manifold and polycarbonate filter membranes are used. Antigen-antibody reactions take place on the membranes. The manifold permits the simultaneous running of 30 samples and a rapid wash technique in which the washing solution is introduced into the manifold wells and suctioned off from below. The polycarbonate membrane offers a distinct advantage over the cellulose acetate in that nonspecific protein adsorption is substantially reduced. Antigens employed are whole bacteria or soluble antigen coupled to Sepharose beads and are layered over the membrane surface. A radiolabeled antibody is used to measure the primary antigen-antibody interaction. The sensitivity of the procedure is equal to that of fluorescent antibody tests. PMID- 4207581 TI - Heterotrophic potential for amino acid uptake in a naturally eutrophic lake. AB - The uptake of sixteen (14)C-labeled amino acids by the indigenous heterotrophic microflora of Upper Klamath Lake, Oregon, was measured using the kinetic approach. The year-long study showed a seasonal variation in the maximum uptake velocity, V(max), of all the amino acids which was proportional to temperature. The maximum total flux of amino acids by the heterotrophic microflora ranged from 1.2 to 11.9 mumol of C per liter per day (spring to summer). Glutamate, asparagine, aspartate, and serine had the highest V(max) values and were respired to the greatest extent. The percentages of the gross (net + respired) uptake of the amino acids which were respired to CO(2) ranged from 2% for leucine to 63% for glutamate. Serine, lysine, and glycine were the most abundant amino acids found in Upper Klamath Lake surface water; at intermediate concentrations were alanine, aspartate, and threonine; and the remaining amino acids were always below 7.5 x 10(-8) M (10 mug/liter). The amino acid concentrations determined chemically appear to be the sum of free and adsorbed amino acids, since the values obtained were usually greater than the (K(t) + S(n)) values obtained by the heterotrophic uptake experiments. PMID- 4207582 TI - Scanning electron microscope study of Neisseria gonorrhoeae. AB - Morphological studies utilizing various microscopy techniques have aided in our understanding of the gonococcus and gonorrhea. In this study scanning electron microscopy was used to study differences in virulent (colony types 1 and 2) and avirulent (colony types 3 and 4) gonococci relative to colony appearance, patterns of growth in liquid media, and surface features of individual cocci. Colony types of virulent gonococci are smaller in diameter but have a higher evaluation than those of avirulent mutants. Colony type 2 has a convex undersurface that is associated with surface pitting of solid media. When the colonies are grown in liquid media, various degrees of autoagglutination are observed; this is most pronounced with type 2 and least evident with type 4. Although pili may be involved in this phenomena, other mechanisms must be employed, since type 3 gonococci that lack pili autoagglutinate. Pili are seen on types 1 and 2 and are absent from types 3 and 4. They appear as individual threads radiating from the bacteria or as bundles of pili attaching adjacent cocci. Another extracellular structure consists of small spherical bodies that can coat the bacteria surface, attach to pili, or exist free from other bacterial components. These spheres are least evident with type 4. The gonococcal surface is pebbly with multiple sulci. PMID- 4207584 TI - Two-trait selection and the genetic correlation. I. Prediction of responses in single-trait and in two-trait selection. PMID- 4207583 TI - Energy dispersion x-ray analysis by scanning electron microscopy for measuring cellular elemental composition in bacterial cells. AB - The use of scanning electron microscopy in conjuction with energy dispersion analysis of X rays is presented as a technique in a novel application to in situ studies of cellular elemental composition. The method has been applied, in the example of its use reported here, to examining the effects of copper chromearsenic wood preservative on growth and element uptake of selected bacteria in agar cultures. PMID- 4207585 TI - Two-trait selection and the genetic correlation. II. Changes in the genetic correlation during two-trait selection. PMID- 4207586 TI - Amniotic fluid vitamin B12-binding protein. Purification and characterization with isoelectric focusing and other techniques. PMID- 4207587 TI - Reaggregation studies on the polypeptide chains of calf lens alpha-crystallin. PMID- 4207588 TI - [Possible existence of a positive feedback of thyroid hormones on thyrotropic function]. PMID- 4207589 TI - Letter: Fascioliasis. PMID- 4207591 TI - [Thermographic observations on changes following ankle sprains]. PMID- 4207590 TI - Controlled trial of various anti-D dosages in suppression of Rh sensitization following pregnancy. Report to the Medical Research Council by the working party on the use of anti-D-immunoglobulin for the prevention of isoimmunization of Rh negative women during pregnancy. AB - In a controlled trial phials containing 200 mug, 100 mug, 50 mug, or 20 mug of IgG anti-D were given to nearly 2,000 D-negative primiparae whose infants were D positive and ABO-compatible. Only mothers whose serum lacked anti-D were included and the dose of anti-D was always given within 36 hours of delivery. Each phial contained the same total volume of immunoglobulin and the particular dose given to any patient was not known to the clinician. The anti-D content of the phials was estimated three times during the course of the trials and remained fairly constant. Six months after delivery the incidence of a positive indirect antiglobulin test result, indicating the presence of anti-D, in the four dose groups (with about 450 women in each group) was as follows: 0.22%, 0.23%, 0.44%, and 1.35%. The trend towards an increase in the frequency of failures as the dose decreases was significant at the level of P=0.02.In each dose group about 200 women were followed to the end of a second pregnancy with a D-positive infant. The failure rates (in order of decreasing dosage) as judged by a positive indirect antiglobulin test result at the second delivery were as follows: 1.5%, 1.1%, 1.5% and 2.9%. The differences between the dose groups were not statistically significant. The overall failure rate (1.7%) was about one-tenth of that expected in an untreated series. Though the results failed to prove any differences in success rates between doses of 200, 100, 50, and 20 mug of anti-D, they do suggest, in conformity with other evidence, that a dose of 20 mug is suboptimal for routine use. The results support the belief that a dose of 100 mug is adequate. PMID- 4207592 TI - Comparative study of the effects of two copper compounds on the respiration and survival of Biomphalaria glabrata (mollusca: pulmonata). PMID- 4207593 TI - Clinical note: seizures and EEG activation after trimipramine. PMID- 4207594 TI - Diazepam treatment for acute convulsions in children. A report of 41 patients, three with plasma levels. PMID- 4207595 TI - Epilepsy in cerebral hydatidosis. PMID- 4207596 TI - Intracarotid pentylenetetrazol injections in the cat. PMID- 4207597 TI - Basilar dendrite bundles of giant pyramidal cells. PMID- 4207598 TI - Behavioral control of firing patterns of normal and abnormal neurons in chronic epileptic cortex. PMID- 4207599 TI - Aeruginocine typing of Pseudomonas aeruginosa. AB - Aeruginocine typing using eight indicator strains of Wahba on Bacto tryptone glucose yeast extract Agar (Difco) with an incubation temperature of 32 degrees C was found to be a reproducible and easy method which could be readily adopted by a diagnostic clinical laboratory. The results of aeruginocine typing of 1500 strains of Ps. aeruginosa suggest that hospitals differ in the range and patterns of aeruginocine types of strains isolated in them. In addition to representatives of nine of the 10 pyocine types of Wahba, a large number of strains isolated in India were found to fall into other groups not described in Wahba's system. Hence, 20 new inhibition patterns (aeruginocine types) are proposed. PMID- 4207600 TI - [Modern diagnosis of ischemic heart disease (based on the data from clinical and angiographic comparison)]. PMID- 4207601 TI - [Serum enzyme activity spectrum in ischemic heart disease]. PMID- 4207602 TI - [Clinical importance of determining the blood carbonic anhydrase activity in congenital heart defects complicated by bacterial endocarditis]. PMID- 4207603 TI - [Pseudoglioma in incontinentia pigmenti (author's transl)]. PMID- 4207604 TI - Anatomy and physiology of the optic nerve head. PMID- 4207605 TI - Cervical mycobacterial disease. PMID- 4207606 TI - Hyperalimentation hypophosphatemia: hematologic-neurologic dysfunction due to ATP depletion. PMID- 4207607 TI - Paradoxical effects of isoproterenol, nitroglycerin and exercise in conscious dogs with myocardial ischemia. PMID- 4207609 TI - The occurrence of antigens of Dermatophagoides farinae Hughes in allergenic extracts of house dust. PMID- 4207608 TI - Temperature, crowding and other environmental pressures in Drosophila melanogaster (adult progeny numger). PMID- 4207610 TI - [Indirect hemagglutination test in chronic chagas disease (author's transl)]. PMID- 4207611 TI - Studies on heterologous immunity in schistosomiasis. 7. Observations on the development of acquired homologous and heterologous immunity to Schistosoma mansoni in baboons. AB - Observations were made on the development of immunity to Schistosoma mansoni in baboons using both homologous and heterologous systems. The baboons were immunized by either (a) a single exposure to cercariae of the homologous species S. mansoni, or (b) 1-2 exposures to cercariae of either a S. rodhaini/S. mansoni hybrid or a S. mattheei/S. haematobium hybrid, or (c) repeated exposure to the cercariae of S. rodhaini or S. bovis. Baboons immunized with 500 cercariae of the homologous parasite developed partial immunity to reinfection, as did the baboons immunized with multiple exposures to the heterologous cercariae of S. rodhaini and S. bovis, although these parasites produced neither adult worms nor eggs in the baboons. The hybrids gave rise to well-established adult worm infections, but produced less immunity, even though the S. rodhaini/S. mansoni hybrid was genetically very similar to S. mansoni. These results indicate that adult worms are not essential to produce a considerable degree of immunity to reinfection, which can be engendered by the earlier stages of the parasites. However, none of the immune responses prevented egg deposition in the tissues, and considerable pathological changes resulted from the challenge infection. These observations suggest that although heterologous infections show some promise as immunizing agents, further studies are needed of the pathological changes resulting from their use. PMID- 4207612 TI - Instability of nitroglycerin tablets. AB - Nitroglycerin is a volatile substance which evaporates from tablets if strict precautions are not taken. The tablets kept in small, amber, tightly capped glass bottles in a refrigerator maintain their potency for three to five months if bottles are opened once a week. After five months the unused tablets should be discarded. Tablets kept in a pill box and carried with the patient will deteriorate in a week and should be discarded thereafter. Cotton, plastic or paper stuffed in the bottle and frequent opening will reduce the potency of NG tablets considerably. Physicians, pharmacists and drug manufacturers should supply full instructions to patients on how to prevent rapid deterioration of their supply. PMID- 4207613 TI - [Sanitary and hygienic characteristics of the aerial method of applying insecticide-microbe mixtures]. PMID- 4207614 TI - [Dynamics of changes in the immune structure of the lymphatic follicles of the spleen in pesticide poisoning]. PMID- 4207615 TI - [Determination of the toxic action of organochlorine compounds by means of cell cultures]. PMID- 4207616 TI - Hippocampal damage and schizophrenia: a critique of Mednick's theory. PMID- 4207618 TI - Vaccination against malaria: evaluation of a plasmodial vaccine fraction and a preliminary study of some immunologic adjuvants in a primate model system: a brief report. PMID- 4207617 TI - Diverticulum of the bladder with ureteral orifice opening into the diverticulum: report of case. PMID- 4207619 TI - The effect of ascorbic acid and potassium ferricyanide as melanogenesis inhibitors on the development of pigmentation in Mexican axolotls. PMID- 4207620 TI - Isolation and characterization of an abnormal human intrinsic factor. AB - A patient has been described previously who presented at age 13 with vitamin B(12) (B(12)) deficiency secondary to a functionally abnormal intrinsic factor (IF). IF has now been isolated from the gastric juice of the patient, his sister, and both parents, who are first cousins, by using affinity chromatography on B(12)-Sepharose. Patient IF appeared normal in terms of (a) B(12) binding, (b) mol wt, (c) total amino acid and carbohydrate composition, and (d) immunodiffusion with rabbit anti-patient and anti-normal IF sera. After adsorption with normal IF, however, anti-patient IF serum precipitated the various IFs as follows: patient IF (> 95%); mother, father, and sister IF (50%); and normal IF (< 10%). Additional adsorption with mother, father, or sister IF completely inhibited the precipitation of patient IF. The association constant determined for patient IF-B(12) and human ileal mucosal homogenates (0.1 x 10(9) M(-1)) was 60-fold lower than that determined with normal IF-B(12) (6.0 x 10(9) M(-1)). Intermediate amounts of ileal IF-B(12) binding were observed with mother, father, and sister IF-B(12). These in vitro studies were supported by multiple Schilling tests, performed with a totally gastrectomized volunteer, that gave the following mean urinary excretions of [(57)Co]B(12): free B(12) (0.5%); + patient gastric juice (2.6%); + mother or father gastric juice (17%); and + normal gastric juice (26%). These studies demonstrate that the patient is homozygous and that the mother, father, and sister are heterozygous for a structurally abnormal IF that has a markedly decreased, but not absent, affinity for ileal IF-B(12) receptors. These studies also indicate that the B(12) and ileal binding sites are located on different portions of the IF molecule. PMID- 4207621 TI - Development of cellular and humoral immunity in the respiratory tract of rabbits to Pseudomonas lipopolysaccharide. AB - Immunization with Pseudomonas lipopolysaccharide induced both cellular and humoral immunity in rabbits, particularly in the respiratory tract after intranasal immunization. Either parenteral (i.m.) or intranasal immunization elicited an IgG antibody response in respiratory secretions, but only intranasal immunization produced secretory IgA antibody. Immunization by both routes stimulated serum IgM and IgG agglutinative antibodies. Because both methods of immunization produced skin test reactivity which had components of both Arthus and tuberculin-like reactions, cellular immunity was more readily assessed by the measurement of migration inhibitory factor (MIF) released from immune lymphocytes in respiratory and spleen cell suspensions after challenge with the lipopolysaccharide antigen. After intranasal vaccination, MIF activity was detected in the respiratory tract by direct assay; in contrast, i.m. immunized rabbits did not produce respiratory MIF. Both modes of immunization resulted in splenic MIF activity. However, lymphocytes were only capable of producing MIF for short periods after primary immunization had ended, apparently losing this function in about 2-3 wk. Therefore, it was concluded that cellular immunity by in vitro assay was transient after primary immunization with this Pseudomonas antigen in contrast to the more persistent humoral immunity. The biological significance of immune lymphocytes as part of the coordinated host defense of the lung needs further evaluation. PMID- 4207622 TI - Thrombocytopenia in experimental trypanosomiasis. AB - The effect of experimental trypanosomiasis on coagulation was studied because a patient in this hospital with Rhodesian trypanosomiasis developed thrombocytopenia with disseminated intravascular coagulation. Rats injected intraperitoneally with this strain of Trypanosoma rhodesiense consistently developed trypanosomiasis and severe thrombocytopenia without changes in hematocrit or concentration of fibrinogen or fibrin split products. At the time of 50% mortality (4-5 days) mean platelet counts per cubic millimeter of infected rats were 18,000+/-9,000 (+/-2 SEM) compared to 1,091,000+/-128,000 in uninfected controls. In vitro, concentrated trypanosomes and trypanosomefree supernates of disrupted organisms added to normal rat, rabbit, or human blood produced platelet aggregation within 30 min. This platelet aggregation was not blocked by inhibitors of ADP, kinins, or early or late components of complement. In vivo thrombocytopenia also occurred in infected rabbits congenitally deficient in C6 and in infected, splenectomized rats. Although the aggregating substance obtained from disrupted trypanosomes is heat-labile, it is active in the presence of complement inhibitors, suggesting that this trypanosomal product may be a protein enzyme or toxin. Since the phenomenon is independent of immune complexes, complement, ADP, and kinins, it appears to represent a new mechanism of microbial injury of platelets and the induction of thrombocytopenia. PMID- 4207623 TI - A serum factor in chronic hypocomplementemic hephritis distinct from immunoglobulins and activating the alternate pathway of complement. AB - Nephritic factor (C3NeF) has been isolated from plasma of patients with hypocomplementemic chronic glomerulonephritis (HCG) by ion exchange and molecular sieve chromatography. This material was further treated with solidified anti-Ig antiserum. The purified material failed to react with antiserum to human IgG, IgG3, Fab, Fc, and kappa and lambda chains, but retained full C3NeF activity. The nonidentity of C3NeF with IgG was further demonstrated by Ouchterlony analysis using anti-IgG and anti-C3NeF. Isolated C3NeF was found to be a protein with a sedimentation coefficient of 7S and a mol wt of 150,000 daltons, which on microzone electrophoresis and gel electrophoresis at pH 8.6 behaved as a gamma globulin. C3NeF is not a C1q precipitin and does not activate the classical complement pathway. Unlike cobra venom factor, it failed to enter into a complex with C3 proactivator (C3PA) when incubated with normal human serum (NHS) and then subjected to sucrose density gradient ultracentrifugation. The action of isolated C3NeF on C3 requires C3PA, C3PA convertase (C3PAse), and properdin (P). Similarly, C3PA conversion by C3NeF requires P, C3PAse, and C3. Total hemolytic activity was lost by incubation of 64 microg of C3NeF/1 ml NHS at 37 degrees C for 30 min. Both C3a and C5a anaphylatoxin could be generated by C3NeF in serum previously depleted of anaphylatoxin inactivator. Anti-C3NeF was found to detect an antigen in all NHS tested. Treatment of NHS with solidified anti-C3NeF caused impairment of the alternate complement pathway. It failed to sustain lysis of glutathione-treated human erythrocytes initiated by inulin. It is conceivable that the normal serum constituent which is removed by anti-C3NeF constitutes the inactive precursor of C3NeF, and a heretofore unrecognized component of the alternate pathway. PMID- 4207625 TI - Susceptibility and immune response to experimental plague in two species of langurs and in African green (grivet) monkeys. PMID- 4207626 TI - Comparison of the immune response to three different Yersinia pestis vaccines in guinea pigs and langurs. PMID- 4207624 TI - Properties of plasminogen activators formed by neoplastic human cell cultures. AB - A series of human cell lines has been examined for fibrinolysis in culture. The sera that are activating for fibrinolysis by human cells are mouse, monkey, human, horse, and bovine. Individual human sera show considerable variation in the ability to activate fibrinolysis. In common with other neoplastic or transformed mammalian and avian cell cultures, human cell lines of neoplastic origin produce substantial amounts of plasminogen activator. Several cultures of nonmalignant origin also produce plasminogen activator, whereas cultures obtained from trypsinized human embryos, or from human embryonic skin do not. The human melanoma plasminogen activators are of two kinds: a major component with a mol wt of 50,000, and a minor species with a mol wt of approximately 60,000. Both are DFP sensitive, serine proteases. PMID- 4207627 TI - Live, attenuated Yersinia pestis vaccine: virulent in nonhuman primates, harmless to guinea pigs. PMID- 4207628 TI - Ultrastructure of Nosema oryzaephili and the taxonomic value of the polar filament. PMID- 4207629 TI - A new species of Pleistophora (Microsporida: Pleistophoridae) parasitic in the shrimp Palaemonetes pugio. PMID- 4207630 TI - Mattesia bombi n. sp. (Neogregarinida: Ophrocystidae), a parasite of Bombus (Hymenoptera: Apidae). PMID- 4207631 TI - Comparative virulence of Nosema plodiae and Nosema heterosporum in the Indian meal moth, Plodia interpunctella. PMID- 4207632 TI - Occurrence of a haplosporidian in native oysters (Ostrea lurida) from Yaquina bay and Alsea bay, Oregon. PMID- 4207633 TI - [Otitis externa]. PMID- 4207634 TI - Lead encephalopathy. Report of a case associated with industrial exposure. PMID- 4207635 TI - Marburg virus disease. PMID- 4207637 TI - [From pedagogics to long term care]. PMID- 4207639 TI - Visualization of catalase on acrylamide gels. PMID- 4207640 TI - Metabolic controls in precancerous liver. V. Loss of control of cholesterol synthesis during feeding of the hepatocarcinogen 3'-methyl-4 dimethylaminoazobenzene. PMID- 4207641 TI - Experimental digital replantation. PMID- 4207636 TI - The vaccination of man and other animals against rabies. PMID- 4207642 TI - The geographic unit as a phase in merging hospital and community programs. PMID- 4207643 TI - I. The future role of the state hospital. PMID- 4207644 TI - 3. Where is my home? The closing of state mental hospitals. PMID- 4207645 TI - Lethal and genetic effects of radiophosphorus decay in bacteriophages SP82G and T7. PMID- 4207647 TI - Is there a future for family medicine? PMID- 4207646 TI - Maximum and optimum in health services. PMID- 4207648 TI - What are comprehensive health services? PMID- 4207649 TI - Priorities and decision making in health planning. PMID- 4207650 TI - The scope and bounds of health economics and medical economics. PMID- 4207651 TI - The occurrence and possible functional significance of -S-S- crosslinks in sperm heads, with particular reference to eutherian mammals. PMID- 4207652 TI - Electrical activity of the motor cortex associated with voluntary movements in the baboon. PMID- 4207653 TI - Remote control system for very small micro-electrode advancens. PMID- 4207654 TI - Emptying the bladder by stimulating sacral ventral roots. PMID- 4207656 TI - Recording from single-cells in infero-temporal cortex of the monkey during discrimination performance. PMID- 4207655 TI - The role of the carotid body chemoreceptors and carotid sinus baroreceptors in the control of cerebral blood vessels. AB - 1. Cerebral blood flow was measured in 17 baboons, anaesthetized with pentobarbitone, paralysed with gallamine and mechanically ventilated and in which the right sinus and both aortic nerves had been cut and the left carotid sinus vascularly isolated. Later in each experiment, the head was artificially perfused with femoral arterial blood via the innominate artery.2. Stimulation of the carotid body chemoreceptors with venous blood invariably caused a rise in regional cerebral blood flow whether the head was naturally or artificially perfused. This response was almost completely abolished if the VIIth cranial nerves were cut intracranially.3. Regional cerebral blood flow varied inversely with carotid sinus pressure.4. After the remaining (left) sinus nerve had been cut, the cerebral vascular response to hypoxia was negligible and the response to hypercapnia was markedly reduced. Blood flow then varied with perfusion pressure.5. These results provide further evidence that cerebral blood vessels are reflexly controlled and that the peripheral arterial receptors are involved. Their action is most conspicuous in the vascular response to hypoxia and together with intrinsic factors in the cerebral vascular bed, they determine the size of the vascular response to changes in CO(2) and pressure. PMID- 4207657 TI - The rapid achievement and maintenance of a steady level of an injected substance in the blood plasma. PMID- 4207658 TI - The compliance of contracting skeletal muscle. AB - 1. The method of controlled releases was used to obtain tension-extension curves in toad (Bufo bufo) sartorii under a variety of conditions at 0 degrees C.2. The curves obtained were approximately linear over a considerable range of force (0.4P(0) to P(0)) if the releases were given from the plateau of tetanic tension. The slope of this linear region was little affected by changes of release velocity in the range 10-120 mm/sec.3. Such changes as did occur with alterations in release velocity could be quantitatively accounted for in terms of the internal shortening predicted by A. V. Hill's two-component model.4. As the muscles were stretched above l(0), we found that the maximum stiffness of the tetanized muscles fell in much the same way as the maximum developed force, P(0).5. In another series of experiments we found a rapid change in the overall shape of the tension-extension curve during the early phase of force development in an isometric tetanus. The stiffness of the muscle increased with increasing developed force during this period.6. The force-velocity curve in these muscles was measured by two methods, both giving a similar result. Surprisingly, toad muscle appears to have about the same intrinsic speed as frog muscle at 0 degrees C. The a.b product from our experiments is considerably greater than the reported values for the maintenance heat rate at 0 degrees C in these muscles.7. The probable site of the variable compliance in active muscle is discussed. It seems most likely that this is within the A-band, perhaps in the cross-bridges themselves. PMID- 4207660 TI - [Current status of geriatric medicine]. PMID- 4207659 TI - [Discussion: the problem of the aged and the society]. PMID- 4207661 TI - [Urinary and fecal incontinence, bedsores and bathing of aged patients]. PMID- 4207662 TI - [Bedside nursing. Nursing intervention in expectant patients with a lack of maternal interest]. PMID- 4207663 TI - [Bedside nursing. Nursing of patients with manic-depressive psychoses in an open ward]. PMID- 4207665 TI - [Clinical conference. Evaluation of the patient's desire for surgery while surgical treatment is not indicated]. PMID- 4207664 TI - [Bedside nursing. Nursing activities at the time of the patient's discharge from the hospital following an extended hospitalization]. PMID- 4207667 TI - [Regional comparison of the supply of health personnel]. PMID- 4207666 TI - [Introduction of foreign literature and discussion: "A Toddler's Separation Anxiety" by Kathleen Schmidt Stephens]. PMID- 4207668 TI - [Introduction to human genetics. 3. Chromosomes. 3. Etiology of chromosome abnormalities]. PMID- 4207670 TI - [Introduction to homeostasis. 3. Physiological stability and regulatory mechanisms as the law of nature]. PMID- 4207669 TI - [Pathophysiology of various diseases. 12. Anemia]. PMID- 4207671 TI - [Works of Carl R. Rogers]. PMID- 4207672 TI - [Self-satisfaction in nursing]. PMID- 4207674 TI - [Opinion survey: self-satisfaction in nursing]. PMID- 4207673 TI - [Discussion: Nursing and the nurse]. PMID- 4207675 TI - [Bedside nursing. Rehabilitation nursing of a patient with a myocardial infarct]. PMID- 4207676 TI - [Bedside nursing. Postoperative nursing of a patient with breast cancer with special emphasis on rehabilitation]. PMID- 4207677 TI - [Nursing approach in a young hysteria patient refusing medication or meals]. PMID- 4207678 TI - [Bedside nursing. Nursing functions for a young schizophrenic patient in the process of becoming self-reliant from the dependency state]. PMID- 4207680 TI - [Clinical conference: speech, motor activities and toilet training in a patient with neuro-Behcet's syndrome]. PMID- 4207679 TI - [Bedside nursing. Nursing activities in the social rehabilitation of the schizophrenic patient rejected from her own family]. PMID- 4207681 TI - [Introduction of foreign literature and discussion. "The Last Hour before Death" by Margaret Walker]. PMID- 4207682 TI - [Analysis of the progress record prepared in clinical training]. PMID- 4207683 TI - [Changes in the total medical expenditures of the population]. PMID- 4207684 TI - [Introduction to human genetics. 4. Twins. 1]. PMID- 4207685 TI - [Environment and man. 1. Overview of environmental medicine]. PMID- 4207686 TI - [Introduction to the study of homeostasis. 4. Autoregulation at the organ and cellular level]. PMID- 4207687 TI - [Abnormal personality. 1. Abnormalities within ourselves]. PMID- 4207688 TI - [Achievement of Carl R. Rogers and the background of his studies]. PMID- 4207689 TI - [Metabolism of normal and diseased cornea (author's transl)]. PMID- 4207690 TI - [What is the cause of atherosclerosis?]. PMID- 4207691 TI - Dopa metabolism by Mycobacterium leprae: its implications in culture of the bacillus and chemotherapy of leprosy. PMID- 4207692 TI - Structure and function of plant microbodies. PMID- 4207693 TI - Population genetics of modifiers of meiotic drive. II. Linkage modification in the segregation distortion system. PMID- 4207695 TI - [Current problems in Swiss health policies. 2]. PMID- 4207694 TI - Use of 18F labelled fluorocarbon-11 to investigate the fate of inhaled fluorocarbons in man and in the rat. PMID- 4207696 TI - Thyroid function through pregnancy and in the fetus and newly born from a goiter endemic in Peru. PMID- 4207697 TI - TSH response to synthetic TRH in endemic goitre. PMID- 4207698 TI - Total serum T3 and TSH response to TRH stimulation in patients with endemic goiter. PMID- 4207699 TI - Some aspects of humoral immunologic reactivity in habitual abortion. (Assay of antitrophoblast IgG, IgA, and IgM by radial immunodiffusion: relationship with leukocyte agglutinating antibodies). PMID- 4207700 TI - Hemolytic uremic syndrome associated with infectious mononucleosis. PMID- 4207701 TI - Arginosuccinicaciduria. The hair abnormality. PMID- 4207702 TI - Congestive heart failure secondary to idiopathic hypoparathyroidism. PMID- 4207703 TI - On the thermodynamics of cell injury. Some insights into the molecular mechanisms. AB - A method is presented for determining the thermodynamic parameters of the rate limiting chemical reaction in cell injury. From these parameters one can deduce certain molecular details of this reaction, such as the number of molecular events required for a specific observable injury, the approximate number of the chemical bonds broken and the degree of molecular configurational change involved. Inactivation of cell division in vitro by heat and by an alkylating agent have been studied by this method. In each case cell injury involved only one to three catastrophic molecular events, which were irreparable within a 3-day period. This suggests that in each case there had been an alteration of a genome essential for cell division. In the case of thermal injury this critical molecular event had the thermodynamic characteristics of a massive configurational change, compatible with the uncoiling of a DNA segment. In the case of alkylation injury the thermodynamic parameters were those of a small localized event with little configurational change and energetically compatible with an alkylation-depurination of DNA. PMID- 4207704 TI - Recently defined onco-fetal antigens and their potential application in clinical medicine. PMID- 4207705 TI - Aspects of dependency. PMID- 4207706 TI - Bacterial degradation of cyclohexane. Participation of a co-oxidation reaction. PMID- 4207708 TI - Serum levels of immune globulins in postmaturity. PMID- 4207707 TI - Comparison of an oral and an intravenous feeding regimen in the newborn. PMID- 4207709 TI - Thyroid status in the newborn infant. Effective thyroxine ratio and free thyroxine index. PMID- 4207710 TI - Proceedings: Problems encountered in design of diets for treatment of protein energy malnutrition. PMID- 4207711 TI - L-threonine deaminase in marine planktonic algae. IV. Studies of substrate specificity and inhibition from substrate analogs. Evidence for additional L serine deaminase activity in the cryptophyte Chroomonas salina. PMID- 4207712 TI - Bacteriolytic and bactericidal activity of sera and synovial fluids in rheumatoid arthritis and in osteoarthritis. PMID- 4207714 TI - Proceedings: Quinidine induced lupus erythematosus. PMID- 4207713 TI - Hemophilus influenzae septic arthritis. A mimicker of gonococcal arthritis. PMID- 4207715 TI - Immunoglobulins in aqueous humour and iris from patients with endogenous uveitis and patients with cataract. PMID- 4207716 TI - Autoimmunity and the retina. II. Raised serum IgM levels in retinitis pigmentosa. PMID- 4207717 TI - Effects of papaverine on the retinal microcirculation. PMID- 4207718 TI - Differential activity of prefrontal units during right and left delayed response trials. PMID- 4207719 TI - Binding of thymus histone F1 and E. coli RNA polymerase to DNA of polytene chromosomes of Drosophila. PMID- 4207720 TI - Different DNA replication behavior of a tandem duplication in Drosophila melanogaster. PMID- 4207721 TI - Pseudomonas osteomyelitis of the metatarsal sesamoid of the great toe. PMID- 4207722 TI - Salmonella Paratyphi osteomyelitis. Report of a case simulating a giant cell tumor. PMID- 4207723 TI - Characterization of the soluble proteins from rabbit eye lens. PMID- 4207724 TI - Single cell activity in the ventral lateral thalamus of the unanesthetized monkey. PMID- 4207725 TI - Preservation of cutaneous temperature sensitivity after ablation of sensory cortex in monkeys. PMID- 4207726 TI - Regional cerebral blood flow of the main visual pathways during photic stimulation of the retina in intact and split-brain monkeys. PMID- 4207727 TI - [Proceedings: Experience with copper T-intrauterine pessary]. PMID- 4207728 TI - Mitogenic effect of a water-soluble extract of Nocardia opaca: a comparative study with some bacterial adjuvants on spleen and peripheral lymphocytes of four mammalian species. PMID- 4207729 TI - Leukemia virus-induced immunosuppression. X. Depression of T cell-mediated cytotoxicity after infection of mice with Friend leukemia virus. PMID- 4207730 TI - Interaction of rheumatoid factor with infectious vaccinia virus-antibody complexes. PMID- 4207731 TI - Sites of localization and synthesis of Ss protein in mice. PMID- 4207732 TI - The binding of alpha-1 antitrypsin to human IgA. PMID- 4207733 TI - Subclavian vein catheterization in the infant. PMID- 4207734 TI - Traumatic prevertebral pharyngoesophageal pseudodiverticulum in the newborn infant. PMID- 4207735 TI - Traumatic perforation of the pharynx in a newborn baby. PMID- 4207736 TI - Urethral diverticulum: complication of abdominoperineal pull-through procedure. PMID- 4207737 TI - Morphogenesis of wheat striate mosaic virus--the internal nucleoprotein component. PMID- 4207738 TI - [The spermatozoon of Nereis irrorata Malmgren (Annelida Polychetes)]. PMID- 4207739 TI - Letter: Primary structure of tuberculin-active protein from tubercule bacilli. PMID- 4207740 TI - Serological typing of Pseudomonas aeruginosa and several points to be considered. PMID- 4207741 TI - Cell proliferation in mouse kidney induced by lead. I. Synthesis of deoxyribonucleic acid. PMID- 4207742 TI - The use of contrast enemas in the diagnosis of neonatal intestinal obstruction. PMID- 4207743 TI - Acute arthritis caused by gram-negative bacilli: a clinical characterization. PMID- 4207744 TI - The mechanism of transfection. Kinetics and nature of B. subtilis transfection by phage SP-50 desoxyribonucleic acid. PMID- 4207745 TI - Specificity of antibodies to the modified DNA of phages SPO1 and T4. PMID- 4207746 TI - The addition of proteins carrying fluorochrome to polytene chromosomes of Drosophila. PMID- 4207747 TI - Letter: Multiple sclerosis and diseased sheep brain. PMID- 4207749 TI - Turkey leucocytozoon infection. 3. Ultrastructure of Leucocytozoon smithi gametocytes. PMID- 4207748 TI - A complex cerebral vascular malformation studied by angiography; multiple aneurysms angiomas and arterial ectasia. PMID- 4207750 TI - Bone ash and duodenal calcium-binding protein in chicks treated with EHDP. PMID- 4207751 TI - [Use of the fluorescent antibody method for microbiological control in the food processing industry (review)]. PMID- 4207752 TI - [Influencing hirsutism with the contraceptive agent Ovosiston]. PMID- 4207753 TI - Outpatient screening for gastrointestinal lesions using guaiac-impregnated slides. PMID- 4207754 TI - Effect of administered human growth hormone on growth retardation in inflammatory bowel disease. PMID- 4207755 TI - Activity of lividomycin against Pseudomonas aeruginosa: its inactivation by phosphorylation induced by resistant strains. AB - The antibacterial activity and enzymatic inactivation of lividomycin, a new aminoglycosidic antibiotic, were studied with 13 strains of Pseudomonas aeruginosa. The minimal inhibitory concentration of lividomycin was 12.5 to 25 mug/ml, and three strains were resistant to high concentrations of lividomycin (more than 200 mug/ml). It was found that P. aeruginosa TI-13 and K-11, highly lividomycin-resistant strains of clinical origin, strongly inactivated the drug. The third resistant strain, Km-41/R, was developed in vitro. Unlike the other resistant strains, Km-41/R, was developed in vitro. Unlike the other resistant strains, Km-41/R did not inactivate the drug, indicating that different mechanisms were involved in lividomycin resistance. By use of a cell-free extract from P. aeruginosa TI-13, the inactivation of lividomycin was found to be caused by the formation of a monophosphorylated product of the drug. PMID- 4207756 TI - Transferable drug resistance in Pseudomonas aeruginosa. AB - Three strains of Pseudomonas aeruginosa were demonstrated to transfer double-drug resistance by conjugation to a P. aeruginosa recipient at frequencies of 10(-4) to 10(-2) per recipient cell. Two of the three strains also transferred to Escherichia coli at frequencies which were 10(3)- to 10(5)-fold lower, but the third strain could not be demonstrated to do so. The latter strain, however, conferred maleness on the Pseudomonas recipient. The transfer of streptomycin resistance was associated with the acquisition of streptomycin phosphorylase by both P. aeruginosa and E. coli recipients. Maximal broth mating frequencies were obtained with nonagitated cultures less than 1 mm in depth. A pyocine selection system based on donor sensitivity and recipient resistance is described and appears to have future value as a generalized selective device for use after matings. PMID- 4207757 TI - Antibiotic synergism against Listeria monocytogenes. AB - The effectiveness of ampicillin, penicillin, streptomycin, and gentamicin against 20 strains of Listeria monocytogenes was studied in vitro. For all strains, the minimal bactericidal concentration (MBC) of both ampicillin and penicillin was much higher than the minimal inhibitory concentration (MIC). The MBC of both streptomycin and gentamicin was close to the MIC, but relatively high concentrations of these antibiotics were necessary to inhibit the growth of most of the strains of Listeria. The combination of penicillin plus streptomycin was synergistic against 19 of 20 strains and in the remaining strain produced enhanced killing (but of less magnitude than our criterion for synergism). Combinations of penicillin plus gentamicin, ampicillin plus streptomycin, and ampicillin plus gentamicin produced enhanced killing against all strains tested. No antagonism was observed when ampicillin or penicillin was combined with streptomycin or gentamicin. PMID- 4207758 TI - Activity of two chlorinated lincomycin analogues against chloroquine-resistant falciparum malaria in owl monkeys. AB - The chloroquine-resistant Oak Knoll strain of Plasmodium falciparum, recently adapted to the owl monkey (Aotus trivirgatus), was insusceptible to chloroquine therapy. Two chlorinated lincomycin analogues tested in this host-parasite system cured blood-induced infections. Acute infections were treated orally for 7 consecutive days with either 15 or 75 mg of clindamycin hydrochloride (U-21) per kg per day, 10 or 50 mg of N-demethyl-4'-pentyl clindamycin hydrochloride (U-24) per kg per day, or 20 mg of chloroquine base per kg per day. These lincomycin analogues cleared trophozoites from the peripheral blood by the end of the 7-day treatment period. The speed of clearance of parasites was not dose-related, but curative activity appeared dependent upon the amount of drug given as well as the number of daily treatments. The efficacy of U-21 and U-24 is of particular interest since they represent major structural departures from compounds commonly used in the treatment of malaria. PMID- 4207759 TI - Relationship between the uptake of isoniazid and its action on in vivo mycolic acid synthesis in Mycobacterium tuberculosis. AB - A direct relationship was established between the rate of uptake of isoniazid and the action of this drug on in vivo mycolic acid synthesis in Mycobacterium tuberculosis H37Ra. The rate of uptake of isoniazid increased linearly with its external concentration and appeared to reach a maximal value of 52 pmoles per hr per 10(9) cells at an external concentration of about 13 mum. Correspondingly, the rate of inhibition of mycolic acid synthesis increased with the rise in the rate of uptake of the drug. A 50% inhibition of mycolic acid synthesis occurred when the uptake of isoniazid reached 5.2 pmoles per 10(9) cells. Calculations showed that this level of drug uptake represents an internal cellular concentration of 9 mum. These results show clearly that the action of isoniazid on the mycolate synthetase system of M. tuberculosis is rapid and that this enzyme system is highly sensitive to the drug. PMID- 4207760 TI - Immunochemical studies on lipopolysaccharide from agglutinable and non agglutinable vibrios. AB - Lipopolysaccharide (LPS) prepared from Vibrio cholerae and a non-agglutinable (NAG; not agglutinable with O-group I serum according to Gardner and Venkatraman [13]) vibrio strain, isolated from a patient with cholera-like clinical symptoms, have been compared with respect to their chemical composition and immunological behavior. In addition to a significant difference in the chemical composition between the two lipopolysaccharides, the LPS from V. cholerae, unlike that from the NAG vibrio, requires prior treatment with alkali for it to be an effective antigen in the indirect hemagglutination test with sheep cells. It has been suggested that the alkali acts by removing excess O-acetyl group from LPS of agglutinable vibrios. LPS from the NAG vibrio consistently showed a lower antibody response in rabbits in terms of agglutinin and vibriocidal titer. Also, the class of agglutinin antibody elicited by LPS of the NAG vibrio was predominantly immunoglobin M, and that from V. cholerae was immunoglobulin G under comparable conditions. PMID- 4207762 TI - Comparative denitrification of selected microorganisms in a culture medium and in autoclaved soil. AB - The denitrifying behavior of selected soil bacteria was compared in a culture solution and in soil that was sterilized by autoclaving. The essential characteristics concerning nitrate reduction and the formation of nitrogenous gases did not change significantly for most bacteria in the two environments. Bacteria whose denitrification product was nitrous oxide evolved the same gas both in soil and in a liquid system, whereas other bacteria formed only nitrogen gas. The validity of laboratory observations in relation to field studies in the domain of denitrification is discussed and evaluated. PMID- 4207761 TI - Some factors affecting the viability of dried bacteria during storage in vacuo. AB - The effects of various substances on the viability of freeze-dried cells of Pseudomonas fluorescens and Salmonella newport were studied during storage in vacuo for 5 years. Mixtures of two organisms were dried together and studied in two factorial experiments. The first was a complete factorial using six factors and two levels; the second was a fractional replicate with four factors at two levels and three others at four concentrations. A study of ribose binding by cells of S. newport was made by using [U-(14)C]ribose. Substantial improvements in viability were obtained by drying in the presence of sucrose, glutamate, and semicarbazide. Low concentrations of ribose increased the death rate during drying, but these adverse effects were prevented by equimolar amounts of semicarbazide. Ribose binding increased with storage time and, although its incorporation changed, most of the increase in total ribose occurred after the main decrease in viability. Storage temperature caused larger changes in viability than did level changes of residual water in the cells. Although the results are complicated by a large number of interactions, they confirm and extend the hypothesis that reactions between carbonyl compounds and cellular components are a major cause of the mortality occurring during storage of dried microorganisms. A particular mixture of sucrose, glutamate, and semicarbazide is proposed as a means of reducing death when prolonged storage in the dry state is desired. PMID- 4207763 TI - Stomach fermentation in East African Colobus monkeys in their natural state. AB - The microbial fermentation in the stomachs of two monkeys, Colobus polykomos, collected in Kenya, was studied. The gas accumulated within the stomach contained H(2) but no CH(4). Volatile fatty acid concentrations were high, but accumulated acid prevented determination of the fermentation rate in untreated, incubated stomach contents. Upon addition of bicarbonate, a very rapid rate could be demonstrated. Some D- and L-lactate were in the stomach contents. Starchy seeds or fruits rather than leaves appeared to have been consumed. Microscopically, the most prominent microorganisms seen were large, very refringent cocci, possibly Sarcina ventriculi, and various smaller cocci and rods. The 28 cultured strains of bacteria included 14 Staphylococcus, 2 Streptococcus, 10 Propionibacterium, and 2 Peptostreptococcus. The culture count constituted 10 to 20% of the direct count. No protozoa or cellulolytic bacteria were found. PMID- 4207764 TI - New system for cultivation of Neisseria gonorrhoeae. AB - A modified Thayer-Martin medium, containing 2.0% agar, 0.25% dextrose, and 5.0 mug of trimethoprim per ml was compared to Thayer-Martin medium for growth of stock cultures of Neisseria gonorrhoeae and for isolation of N. gonorrhoeae from clinical specimens. Stock cultures and male urethral cultures grew equally well on both media, but the modified Thayer-Martin medium detected 10% more female patients positive for gonococci. A description is given of the use of a citric acid-sodium bicarbonate tablet for generating carbon dioxide in a sealed plastic bag containing a culture plate. Equivalent results were obtained on duplicate plates of 336 cultures and specimens when this procedure was compared with the standard candle jar extinction method of incubation. The tablet and plastic bag system has the advantages of economy, ease of use, and safety. PMID- 4207765 TI - Some observations on the propagation of avian infectious bronchitis virus in tissue culture. PMID- 4207766 TI - Agglutination of red blood cells by polyelectrolytes and antibodies. PMID- 4207767 TI - Velocity profiles in the retinal microcirculation. PMID- 4207768 TI - Two outbreaks of Bacillus cereus food poisoning in Canada. PMID- 4207769 TI - Editorial: Acute cavitary histoplasmosis--fact or fiction? PMID- 4207770 TI - Lower lung field tuberculosis. PMID- 4207771 TI - Right coronary arterial spasm causing Prinzmetal's variant angina. PMID- 4207772 TI - Serotaxonomy of Aotus. A preliminary study. PMID- 4207773 TI - [Locomotory trends in primates expressed by the foot ratios. The adaptation to bipedalism (author's transl)]. PMID- 4207774 TI - Distribution, divergence and speciation of the drill and mandrill. PMID- 4207775 TI - Parental care in a group of free-ranging rhesus monkeys (Macaca mulatta). PMID- 4207776 TI - Social structure of the squirrel monkey (Saimiri sciureus, Iquitos): relationships among behavior, heartrate, and physical distance. PMID- 4207778 TI - [Prolonged intravenous feeding in surgical patients]. PMID- 4207777 TI - Interrelationship of blood groups between rhesus macaques (Macaca mulatta) and Celebes ape (Macaca niger). PMID- 4207779 TI - Immediate surgical repositioning of one- and two-tooth dento-osseous segments. PMID- 4207780 TI - Prevention of postoperative symptoms by general antibiotic treatment and local bandage in removal of mandibular third molars. PMID- 4207781 TI - Neomycin-bacitracin cones in impacted third molar sockets. PMID- 4207782 TI - Unusual complication following surgically treated fracture of the mandibular condyle. PMID- 4207783 TI - Fibrosarcoma of the tongue. PMID- 4207784 TI - The evaluation of ankle pathology with arthrography. PMID- 4207785 TI - M-81, a new peptide antibiotic produced by Streptomyces griseus subsp. Psychrophilus at moderate temperature. PMID- 4207786 TI - On the mode of action of hodydamycin. PMID- 4207787 TI - Cryomycin and M-81 production from hexamethylenediamine. PMID- 4207788 TI - New metabolic products of Aspergillus flavus. IV. 4'-Hydroxyasperentin and 5' hydroxyasperentin 8-methyl ether. PMID- 4207789 TI - Cytological evidence for catecholamine-containing sensory cells bordering the ventricle of the toad hypothalamus. PMID- 4207790 TI - Antibodies to sperms and seminal plasma in infertile couples. PMID- 4207791 TI - Comparison of three serological methods for the detection of hepatitis-associated antigen. PMID- 4207792 TI - Laboratory aspects of gonorrhea control. II. PMID- 4207793 TI - Replacement of functional parenchymal cells by fat and connective tissue in human submandibular salivary glands: an age-related change. PMID- 4207794 TI - Total body irradiation effects on the bone resorption mechanism in rats subjected to orthodontic movements. PMID- 4207795 TI - A comparative assay of the in-vitro and in-vivo behavior of three chemically induced neoplasms of rat submandibular glands. PMID- 4207796 TI - Observations on the ultrastructure of the epithelium in oral lichen planus. PMID- 4207797 TI - The experimental production of odontogenic keratocysts. PMID- 4207798 TI - Electron microscopy of enamel surface after reactions of apatite accretion. PMID- 4207799 TI - The acquired pellicle: variability and subject-dependence of specific proteins. PMID- 4207800 TI - The immunology of cancer. PMID- 4207801 TI - Microradiographic study of human temporomandibular disks obtained at autopsy. PMID- 4207802 TI - Clinicopathological Conference of The Medical University of South Carolina. "A young man with recurrent hemopytsis and renal failure". PMID- 4207803 TI - [A case of phenytoin intoxication]. PMID- 4207804 TI - [Detection of Australia antigen with a radioimmunological method]. PMID- 4207806 TI - [Cyclopia. Report of a case]. PMID- 4207805 TI - [Carbenicillin]. PMID- 4207807 TI - [Congenital Chagas' disease. Clinico-pathological study of a case with 6 months' survival]. PMID- 4207808 TI - Defensive use by an insect of a plant resin. AB - Larvae of the sawfly Neodiprion sertifer (Hymenoptera: Diprionidae), when disturbed, discharge an oily oral effluent essentially identical chemically to the terpenoid resin of its host plant (Pinus sylvestris). The resin is sequestered by the larva upon feeding, and stored in two compressible diverticular pouches of the foregut. The fluid is effectively deterrent to predators. The defensive use by an insect of a plant resin provides an instance of secondary utilization by a herbivore of the protective chemical weaponry of its host. PMID- 4207809 TI - [Pathomorphosis of infiltrative-pneumonic tuberculosis]. PMID- 4207810 TI - Medical Grand Rounds: from the Department of Medicine, University of Virginia Medical Center. Meningococcal meningitis and meningococcemia. PMID- 4207811 TI - A note on the susceptibility of sheep and goats to East Coast fever. PMID- 4207812 TI - [Use of the indirect immunofluorescence test in a study of the etiology of human leukemia in experiments on monkeys]. PMID- 4207814 TI - [Mixed IgM-IgG cryoglobulinemia in a patient with Waldenstrom's macroglobulinemia]. PMID- 4207813 TI - [Biological properties of the agent of bovine enteritis as a representative of the OLT (ornithosis-lymphogranuloma-trachoma) group]. PMID- 4207815 TI - Timely topics in microbiology, 1972: gram positive. PMID- 4207816 TI - Results and problems of O-Glycoside synthesis. PMID- 4207817 TI - Recent discoveries in the evolution of protein. PMID- 4207818 TI - [Treatment of acute fulminant hepatitis with heparin and diuretics]. PMID- 4207819 TI - [Clinical analysis of 208 cases of primary myocarditis in children]. PMID- 4207820 TI - [Survey on the refractive state among primary and middle school students in Tsinan]. PMID- 4207821 TI - [Therapeutic observation of intravenous doxycycline combined with trimethoprim in the treatment of pulmonary infections in chronic cor pulmonale]. PMID- 4207822 TI - [Toxicity and pharmacologic study of doxycycline]. PMID- 4207823 TI - [Repair of a facial defect using a free skin island flap with vascular anastomoses: a case report]. PMID- 4207824 TI - [Manubrium sterni with bilateral sternoclavicular joint homograft: a case report]. PMID- 4207825 TI - [Radix Salviae miltiorrhizae-Rhizoma Corydalis decoction and nicotinic acid solution iontophoresis to the precordium in the treatment of angina pectoris]. PMID- 4207826 TI - [Surgical treatment of secundum atrial septal defect]. PMID- 4207827 TI - [Urinary excretion of estriol and human chorionic gonadotrophin in the late stage of pregnancy in relation to pathologic changes of the placenta and their clinical significance]. PMID- 4207828 TI - [Flush blood pressure in 100 normal full-term infants]. PMID- 4207829 TI - [Clinicopathological conference: case no. 13--coughing. excessive phlegm, jaundice and liver enlargement]. PMID- 4207830 TI - The effects of prefrontal lobotomy on aggressive behavior in dogs. PMID- 4207831 TI - Mycoplasma bovigenitalium: experimental induction of genital disease in bulls. PMID- 4207832 TI - Hepatitis associated antigen in blood donors in Ethiopia. PMID- 4207833 TI - [New developments in the treatment of venereal diseases]. PMID- 4207834 TI - Rumen microbial numbers in lambs as affected by level of feed intake and dietary diethylstilestrol. PMID- 4207835 TI - Regional circulatory adjustments to eating and digestion in conscious unrestrained primates. PMID- 4207836 TI - Intraluminal diverticulum of the duodenum: report of a case with roentgenologic and endoscopic appearance. PMID- 4207837 TI - [Certain socioeconomic aspects of injuries in agriculture]. PMID- 4207838 TI - [Changes in the epiphyseal cartilage following long term treatment with glucocorticoids]. PMID- 4207839 TI - [Epidemiology of Salmonella infections]. PMID- 4207840 TI - [Listeria infections: some aspects of human and animal infection]. PMID- 4207841 TI - [Ecological aspects of American trypanosomiasis. V. Observations on spontaneous wild triatomide colonization in artificial ecotopes with special reference to Triatoma sordida]. PMID- 4207842 TI - [Determination of house infestation by Triatoma sordida]. PMID- 4207843 TI - [Psychomotor seizures in generalized epilepsy]. PMID- 4207844 TI - [Changes of the number and properties of intestinal microflora in children with coli-infections]. PMID- 4207845 TI - [Isolation of atypical Mycobacteria from the patients with tuberculosis and methods of their primary identification]. PMID- 4207846 TI - [Who will pay for that?]. PMID- 4207847 TI - [Pharyngeal gonorrhea]. PMID- 4207848 TI - [Routine culture for gonococci in a family planning clinic]. PMID- 4207849 TI - Contributions to the optimal use of human blood. 3. Large-scale preparation of human c1 esterase inhibitor concentrate for clinical use. PMID- 4207850 TI - An international proficiency survey for the detection of hepatitis B antigen and antibody in blood donations by counterimmunoelectrophoresis. PMID- 4207851 TI - Presence of chronic lymphoid leukaemia associated antigen in other malignant haematological diseases. PMID- 4207852 TI - [Cytostatic therapy of metastasizing breast cancer]. PMID- 4207853 TI - [For and against administration of the so-called geriatric drugs]. PMID- 4207854 TI - [Activity of serum carboanhydrase in zinc depletion of growing rats. 7. Zinc metabolism in the animal organism]. PMID- 4207855 TI - [Relationships between gastroduodenal ulcer, stomach cancer and blood groups]. PMID- 4207857 TI - Sexual differences in the anterior dentition in African primates. PMID- 4207856 TI - [Indications and results of uterine tocolysis]. PMID- 4207858 TI - Canine role in dental wear patterns: Macaca nemestrina. PMID- 4207859 TI - Thermal solubility of gene 8 coast protein in 2 M urea for fd phage. PMID- 4207860 TI - Chemical modification of tyrosine residue in "toxin B" from the venom of the Indian cobra, Naja naja. PMID- 4207861 TI - Effects of carboxyhemoglobin on the determination of methemoglobin in blood. PMID- 4207862 TI - Prolonged remissions of lymphatic leukemia in DBA-2 mice induced with endogenously produced lactate dehydrogenase antibody. PMID- 4207863 TI - Assay of phospholipids in the amniotic fluid. PMID- 4207864 TI - Insulin: a comparison of the results of plasma and serum assays using a double antibody technique. PMID- 4207865 TI - The occurrence and nature of precipitating antibodies in anti-DNA sera. PMID- 4207866 TI - Purification and properties of S-100 protein from porcine brain. PMID- 4207868 TI - Sensitivity of Escherichia coli to viral nucleic acid. VII. Further studies on Ca2+-induced competence. PMID- 4207867 TI - L-histidine ammonia-lyase in rat liver. I. Purification and general characteristics. PMID- 4207869 TI - Biosynthesis of seminolipid: sulfation in vivo and in vitro. PMID- 4207870 TI - Formation and reversion of Streptomycete protoplasts: cultural condition and morphological study. PMID- 4207871 TI - Mesosomes in Bacillus cereus 569 and the production of extra membranes by treatment with actinomycin-D. PMID- 4207872 TI - Effects of sodium dodecyl sulphate on the structure of purified pyocin sheaths. PMID- 4207873 TI - An investigation by autoradiography and electron microscopy of the localization of prenols in Lactobacillus casei. PMID- 4207874 TI - Biologic characteristics of transformed rhesus foreskin cells infected with Mason Pfizer monkey virus. PMID- 4207875 TI - Failure of buffered 5-hydroxytryptamine to increase brain capillary permeability to albumin in monkeys. PMID- 4207876 TI - Myiasis of the external auditory meatus. PMID- 4207877 TI - The value of alpha-fetoprotein in the prenatal diagnosis of neural tube defects. PMID- 4207878 TI - Location of double bonds in long chain esters by methoxymercuration-demercuration followed by mass spectroscopy. PMID- 4207879 TI - [Preventive vaccination in pregnancy]. PMID- 4207880 TI - [Typing of pseudomonas aeruginosa in patients injured by burns (author's transl)]. PMID- 4207882 TI - [Rampant caries in pre-school children]. PMID- 4207881 TI - Pyruvate carboxylase cold inactivation and sulfhydryl groups. PMID- 4207883 TI - [Dentigerous cyst of the jaws, report of a case]. PMID- 4207884 TI - [The mandibular canal and course of the inferior alveolar nerve]. PMID- 4207885 TI - [Evaluation of cephalometry in the diagnosis and prognosis of malocclusion]. PMID- 4207886 TI - Further parasites of the family Garniidae (Coccidiida: Haemosporidiidea) in Brazilian lizards. Fallisia effusa gen.nov., sp.nov. and Fallisia modesta gen.nov., sp.nov. PMID- 4207887 TI - Minor physical anomalies and neurologic status in hyperactive boys. PMID- 4207888 TI - [Biosynthesis of alpha-amylase by microorganisms]. PMID- 4207889 TI - [Comparative study of the enzyme activity and inhibition of terrilytin and proteases with thrombolytic activity]. PMID- 4207891 TI - [Studies of the distribution of blood groups and Rh factor in 20 towns of the province of Verona]. PMID- 4207890 TI - [Pectolytic enzymes of Clostridium felsineum]. PMID- 4207892 TI - [Quantitative evaluation of Australia antigen]. PMID- 4207893 TI - An unusual lymphoma of the palate. PMID- 4207895 TI - [Total parenteral feeding in pediatrics]. PMID- 4207894 TI - [Intravenous feeding in pediatric surgery and pediatrics. A summary of 7 years of research and routine]. PMID- 4207896 TI - Metabolism of the hydroxyethylrutosides. II. Excretion and metabolism of 3',4',7 tri-O-(beta-hydroxyethyl) rutoside and related compounds in laboratory animals after parenteral administration. PMID- 4207897 TI - [Diurnal dynamics of conditioned reflex activity and several autonomic indices in monkeys with experimental neurosis]. PMID- 4207898 TI - [Comparative stability of conditioned reflexes to relative and absolute stimulus cues in bears]. PMID- 4207899 TI - On the nature of the haploid syndrome in Bufo arenarum. PMID- 4207900 TI - Mycolonus epilepsy with cherry-red spot in adult: a peculiar form of mucopolysaccharidosis. (A clinical genetic, chemical and ultrastructural study). PMID- 4207901 TI - Maintenance treatment of chronic schizophrenia with neuroleptic drugs. PMID- 4207902 TI - Radiation quality independent liquid ionization chamber for dosimetry of electron radiation from medical accelerators. PMID- 4207903 TI - Gastrointestinal protein loss induced by 60Co irradiation of the abdomen in mice. PMID- 4207904 TI - Effect of radiation treatment on cell-mediated immune response in carcinoma of the breast. PMID- 4207905 TI - Reaction of bromoacetazolamide with crystals of human carbonic anhydrase C. PMID- 4207907 TI - Fibrin gel structure: influence of calcium and covalent cross-linking on the elasticity. PMID- 4207906 TI - Nonidentity of liver alcohol dehydrogenase and the principal protein target of hepatic azocarcinogen. PMID- 4207909 TI - Immunologic and electrophoretic identity between nervous system-specific proteins antigen alpha and 14-3-2. PMID- 4207908 TI - Nitrogen isotope effects on the papain-catalyzed hydrolysis of N-benzoyl-L argininamide. PMID- 4207910 TI - Intimal thickening in normocholesterolemic rhesus monkeys fed low supplements of dietary cholesterol. PMID- 4207911 TI - Prostaglandin B2-induced cutaneous vasoconstriction of the canine hind paw. PMID- 4207912 TI - Measurement of IgG and albumin content of cerebrospinal fluid, and its interpretation. PMID- 4207913 TI - Ascaridia galli: effects of immunosuppressive drugs or bursectomy in chickens. PMID- 4207914 TI - Theileria annulata: cross-reactions between a cell culture schizont antigen and antigens of East African species in the indirect fluorescent antibody test. PMID- 4207915 TI - Lack of protection against Trypanosoma cruzi by multiple doses of T. lewisi culture forms. A discussion on some strains of "lewisi". PMID- 4207916 TI - Hymenolepis diminuta: an electron microscope study of ion absorption. PMID- 4207917 TI - Protein uptake by the intestine: evidence for absorption of intact macromolecules. PMID- 4207918 TI - Changes in intestinal lactase and alkaline phosphatase activity levels with age in the baboon (Papio papio). PMID- 4207919 TI - A million procrustean beds. PMID- 4207920 TI - [Chronic viral hepatitis in childhood. 24 cases including 5 sibling pairs]. PMID- 4207921 TI - Anaerobic bacteria isolated from decubitus ulcers. PMID- 4207923 TI - Radioimmunoassay methods for carcinoembryonic antigen. PMID- 4207924 TI - Combination of absorption technique and alpha-amylase activity determination in the same gel medium. PMID- 4207922 TI - Diagnostic serology inhuman mycoplasmas. PMID- 4207925 TI - The measurement of IgG anti-IgG antibody in rheumatoid arthritis. PMID- 4207926 TI - Reversed electroimmunodiffusion for quantitating precipitins. PMID- 4207927 TI - Haemaccel--an improved diluent for incomplete enzyme treated anti-Rh serum. PMID- 4207928 TI - The use of cholera toxin for obtaining rabbit secretory immunoglobulins. PMID- 4207929 TI - The antigen and virus of Aleutian disease in mink. PMID- 4207931 TI - Micro-capillary agglutination. PMID- 4207930 TI - A method for demonstrating mono- and oligomeric units of IgA myeloma proteins in the mouse. PMID- 4207932 TI - A two-stage method for cross-linking antibody globulin to ferritin by glutaraldehyde. II. Antigen binding and agglutinating capacity. PMID- 4207933 TI - Superior colliculus neurons studied during head and eye movements of the behaving monkey. PMID- 4207934 TI - Studies on mechanism of inhibition of cardiac muscle contractile tension by ryanodine. Mechanical response. PMID- 4207935 TI - Evaluation of the effects of the finger fracture technique used in hepatic resection. PMID- 4207936 TI - [Cross reactions in the serological diagnosis of Chagas' disease and Kala-azar including sera of tuberculous and leprous patients (author's transl)]. PMID- 4207937 TI - [Lipid histochemical studies of myelodestruction in purulent leptomeningitis]. PMID- 4207938 TI - Histochemical study of few enzymes in the adrenaline treated heart of fresh water crab, Paratelphusa masoniana. PMID- 4207939 TI - Action of exogenous thymidine in vivo on progenitor cell cycle in intestinal epithelium. PMID- 4207940 TI - [Suitability of monotetrazolium salt MTT derivatives for histochemical dehydrogenase demonstration]. PMID- 4207941 TI - [Microchemical and histochemical studies of lactate dehydrogenase and malate dehydrogenase in the pancreas of some birds and mammals]. PMID- 4207942 TI - Cytochemical investigations of the metabolism of alveolar and peritoneal macrophages. PMID- 4207943 TI - [Dye analytical studies of rhodamines. V. Stagoscopic studies of rhodamin B]. PMID- 4207944 TI - Ultrahistochemical demonstration of positively charged groups at the surface of human red blood cells. PMID- 4207945 TI - [Chemical-analytical characterization of glutaraldehyde in fixing solutions]. PMID- 4207947 TI - I. Distribution of urea-stable and urea-labile lactate dehydrogenase activity in rabbit aorta following a single mechanical dilatation injury: a histochemical study on methodology and histotopography. PMID- 4207946 TI - Effect of estradiol on the mouse female reproductive system in organ culture. PMID- 4207948 TI - [Histochemical enzyme demonstration in rat aortas in paraffin section]. PMID- 4207949 TI - [Suitablity of brillant black (C.I.No. 27260) for histochemical demonstration of tissue proteins]. PMID- 4207950 TI - [Annual cyclic studies of catecholamines in the hypothalamus of Triturus vulgaris (L.)]. PMID- 4207951 TI - [Acid-alkaline state of the amniotic fluid in normal pregnancy and in RH immunization]. PMID- 4207952 TI - Comparative recovery of 1972-1973 influenza virus isolates in embryonated eggs and primary rhesus monkey kidney cell cultures after one freeze-thaw cycle. PMID- 4207953 TI - Antimycobacterial activity of some quinolyl aryl sulfides, sulfones, and ethers, in vitro. AB - A series of 61 compounds of six different categories (nitrosulfides, nitrosulfones, aminosulfides, aminosulfones, nitroethers, and aminoethers), all heterocyclic analogues of diaminodiphenyl sulfone (DADS), were synthesized by replacing one of the benzene rings of DADS by a 5-nitro-quinoline ring and the other benzene ring by various heterocyclic nuclei. Among these compounds, 51 were found to inhibit the growth of Mycobacterium tuberculosis at a concentration of 40 mug or less per ml; 8 compounds were effective at a concentration of 1 mug/ml and 9 were effective at a concentration of 0.1 mug/ml. 5-Amino-8-quinolyl-2,4 dichlorophenyl sulfide was found to be 20 times more effective than isonicotinic acid hydrazide and 80 times more effective than streptomycin. PMID- 4207954 TI - Butirosin, a new aminoglycosidic antibiotic complex: bacterial origin and some microbiological studies. AB - Butirosin, a new aminoglycosidic antibiotic complex, was produced by submerged fermentation with each of two strains of Bacillus circulans. A paper-disc, agar diffusion assay which employs Escherichia coli (P-D 04863) as the test organism has been developed. Shaken-flask and stirred-jar fermentations in a medium containing glycerol, soybean meal, meat peptone, ammonium chloride, and calcium carbonate reach titers of 500 to 700 mug of butirosin base per ml. Butirosin is active against several gram-positive and gram-negative bacteria including Pseudomonas aeruginosa. PMID- 4207955 TI - Concentrations of ampicillin and chloramphenicol in the serum of patients with acute Salmonella enteric fever. AB - Concentrations of ampicillin and chloramphenicol were measured in the serum of patients being treated for acute infections by Salmonella typhi or S. paratyphi A. Ampicillin was administered by the oral or intramuscular routes, whereas chloramphenicol was given orally only. Ampicillin concentrations were highest 1 hr after initiation of intramuscular therapy and 2 hr after oral administration. The serum concentration of ampicillin was significantly higher when it was given intramuscularly than when it was given orally. However, serum concentrations in orally treated patients were approximately the same at 1 hr after the fifth dose as they were 1 hr after the first dose, in contrast to intramuscularly treated patients, in whom the serum concentration of ampicillin was significantly lower 1 hr after the fifth dose. On the other hand, serum concentrations of chloramphenicol were significantly higher after the fifth dose than after the first dose. The rates of cure, relapse, and drug treatment failure were similar for all treatment regimens, and the drug concentrations attained in serum were generally above the minimal inhibitory concentration for the infecting salmonellae. PMID- 4207956 TI - Inhibition of growth of T-strain mycoplasmas by hydroxamic acids and by aurothiomalate. AB - Sorbyl-, benzoyl-, and 3-amino-benzoyl hydroxamic acids inhibited the development of an alkaline pH by T-strain cultures grown in broth containing 0.05% urea and phenol red. The specificity of this urease inhibition was demonstrated by the inhibition, by 10(-4)m sorbyl-hydroxamic acid, of the release of (14)CO(2) from (14)C-urea by washed T-strain mycoplasmas in 4 hr of incubation. Sorbyl-, benzoyl , and 3-amino-benzoyl hydroxamic acids at a concentration of 10(-3)m markedly inhibited the multiplication of T-strain 354 during 18 hr of incubation; this inhibition was not corrected by thymidine at a concentration of 500 mug per ml. Aurothiomalate was 20 times more inhibitory to Mycoplasma hominis DC-63 than to T strain 354; equivalent inhibitory concentrations were 50 mug per ml for M. hominis and 1,200 mug per ml for T strains. PMID- 4207957 TI - Simple photometric assay of beta-lactamase activity. AB - A simple photometric assay of beta-lactamase activity was developed. The method is based on a decrease in optical density at 620 nm caused by the formation of a penicilloic acid-iodine complex. The enzymatic reaction is instantaneously stopped by the addition of a concentrated iodine-tungstate solution. Data showing the time and concentration dependence of the reaction are presented. By varying both the time of the assay and the concentration of the enzyme, substrates of widely different V(max) values could be assayed. The assay is compared with other methods of determining beta-lactamase activity. PMID- 4207958 TI - Uptake and binding of 14C-ethambutol by tubercle bacilli and the relation of binding to growth inhibition. AB - Studies were designed to characterize ethambutol uptake by Mycobacterium tuberculosis (H37Ra) and to relate uptake to the time-dependent, concentration independent nature of growth inhibition by ethambutol. When cells grown aerated at 37 C in Sauton medium were exposed for 7 hr to 0.2, 0.5, 1.0, 2.5, and 5.0 mug of (14)C-ethambutol per ml, uptake increased with time and was a linear function of concentration. The process was inhibited at 22 C. Studies with chloramphenicol, sodium azide, and 2,4-dinitrophenol indicated that uptake is independent of requirements for protein synthesis and energy. The organism did not accumulate ethambutol against a concentration gradient. It can be concluded that ethambutol enters the cells in a passive manner. Kinetic studies of (14)C loss from tubercle bacilli pretreated with labeled drug suggested the existence of two ethambutol fractions within the cell: a highly variable labile pool and a second fraction that is small and quite firmly bound. Levels of cell-bound drug may be independent of total uptake, but this possibility was not established unequivocally. Definitive evidence showing identity in the concentrations of bound drug regardless of total uptake could explain the apparent discrepancy between concentration-dependent uptake and concentration-independent growth inhibition. PMID- 4207959 TI - The role of lysosomes in production of ischemic nerve cell changes. PMID- 4207960 TI - Cue-locus--a factor in the behavioral deficiency of the developing protein malnourished monkey (Macaca Mulatta). PMID- 4207961 TI - Editorial: Methoxyflurane nephrotoxicity. PMID- 4207962 TI - Editorial: Gonorrhoea of the pharynx. PMID- 4207963 TI - Diagnosis and treatment of essential fatty acid deficiency in man. AB - Essential fatty acid deficiency was found on four occasions in three adult patients with malabsorption after intestinal resection. Diagnosis was primarily based on the gas chromatographic finding of the abnormal fatty acid 5, 8, 11- (omega9) eicosatrienoic acid in plasma lecithin. None of the patients had received parenteral nutrition with a fat-free source of calories but all had been on a reduced intake of dietary fat at some stage. Treatment with intravenous Intralipid rapidly reversed the abnormal plasma fatty acid pattern and also cleared the rash in the patient wih he most severe deficiency. PMID- 4207964 TI - Prevalence of hepatitis B antigen and antibody in prostitutes. AB - We investigated the prevalence of hepatitis B antigen (HBAg) and antibody (HBAb) in 293 prostitutes and in 379 pregnant women of similar age and of low socioeconomic level, who served as controls. HBAg was found in 4.4% of prostitutes and 3.4% of controls. The prevalence of HBAb was significantly higher (P <0.001) in prostitutes (56.7%) than in controls (24.5%). The prevalence of HBAb was clearly age-dependent in both groups. Evidence of hepatitis B virus infection significantly increased with the number of years in prostitution. The evidence of increased infection rates among prostitutes and their distribution support the hypothesis that hepatitis B infection is sexually transmitted. PMID- 4207965 TI - "Anticonvulsant action" of vitamin D in epileptic patients? A controlled pilot study. AB - The frequency of epileptic seizures was observed in a controlled therapeutic trial on 23 epileptic inpatients before and after treatment with vitamin D(2) or placebo in addition to anticonvulsant drugs. The number of seizures was reduced during treatment with vitamin D(2) but not with placebo. The effect was unrelated to changes in serum calcium or magnesium. The results may support the concept that epileptics should be treated prophylactically with vitamin D. PMID- 4207966 TI - Immunochemical method for quantitative estimation of an inducible enzyme- lupanine hydroxylase. PMID- 4207967 TI - Chemically defined diets. PMID- 4207968 TI - Complications of intravenous alimentation in seriously ill infants. PMID- 4207969 TI - The Furbringer hypothesis of nerve-muscle specificity reexamined with respect to the facial musculature. PMID- 4207970 TI - Clinical experiences with the use of cromolyn sodium in asthmatic children. PMID- 4207971 TI - Selection of patients for cromolyn therapy. PMID- 4207972 TI - Asthma. Panel discussion. Question and answer session. PMID- 4207973 TI - Asthma control: an update. PMID- 4207974 TI - [2 cases of hereditary dentin dysplasia]. PMID- 4207975 TI - Analysis of tRNAs during the development of Drosophila. PMID- 4207976 TI - Expression of xanthine dehydrogenase activity during embryonic development of Drosophila melanogaster. PMID- 4207977 TI - The maternal and zygotic control of development by cinnamon, a new mutant in Drosophila melanogaster. PMID- 4207978 TI - The synthetic and minimal culture requirements for evagination of imaginal discs of Drosophila melanogaster in vitro. PMID- 4207979 TI - Variations in myoneme birefringence in relation to length changes in Stentor coeruleus. PMID- 4207980 TI - The shuttling activity of nuclear RNAs is not an artefact of experimental manipulation. PMID- 4207981 TI - The oral apparatus of Tetrahymena pyriformis, mating type 1, variety 1. I. Solubilization and electrophoretic separation of oral apparatus proteins. PMID- 4207983 TI - Personnel practices in long-term care facilities. PMID- 4207982 TI - [Recent statistical data concerning perinatal mortality]. PMID- 4207985 TI - [Pseudomonas aeruginosa. II. Serotyping and virulence of the organism against mice and guinea pigs and its sensitivity to antibiotics]. PMID- 4207986 TI - [DNAase activity of the diphtheria bacteria as one of the signs of their pathogenicity]. PMID- 4207984 TI - Polycarboxylate cement as a pulp capping agent. PMID- 4207987 TI - [Detection of the A-1 virus of the blue-green alga Anabaena variabilis in the Kremenchug artificial reservoir]. PMID- 4207988 TI - [Bacteria of the genus Pseudomonas in the pathology of insects]. PMID- 4207989 TI - [Precocious pulmonary emphysema and alpha-1-antitrypsin deficiency. Research on the deficiency in 222 cases of respiratory insufficiency]. PMID- 4207990 TI - Carbamazepine for epilepsy. A controlled prospective evaluation. PMID- 4207991 TI - Radionuclide scanning and microangiography of evolving and completed brain infarction. A correlative study in monkeys. PMID- 4207992 TI - Simultaneous measurement of internal and external carotid blood flow in the monkey. An approach to the study of migraine mechanisms. PMID- 4207993 TI - [Intraluminal duodenal diverticulum causing differential diagnostic problems]. PMID- 4207995 TI - Effect of synthetic salmon calcitonin on iodine metabolism in rabbits. PMID- 4207994 TI - Role of histaminase and corticosterone on the depletion of tissue histamine in the irradiated rats. PMID- 4207996 TI - [Radiotherapy of the carcinoma of the anus (author's transl)]. PMID- 4207997 TI - [Value of repeated scanning in the evaluation of ectopic bone formation in paraplegics (author's transl)]. PMID- 4207998 TI - The immunosuppressive potency of antilymphocyte serum is related to activity against human thymic lymphocyte-specific antigens. PMID- 4208000 TI - [Myeloarchitecture of cerebellar cortex]. PMID- 4207999 TI - [Experimental studies on formation of the neural tube in chick embryos]. PMID- 4208001 TI - [Autofluorescent granules in the ependyma of recessus inframamillaris of young prickle mice (Acomys cahirinus dimidiatus)]. PMID- 4208002 TI - [Studies on fine structure of choroid plexus and ependyma in monkeys (with remarks to function)]. PMID- 4208003 TI - [Interrelationships between skin surface and touch apparatus of the skin in various mammals]. PMID- 4208004 TI - [Capillaries of cerebellar cortex in the cat and in the rhesus monkey]. PMID- 4208005 TI - [Australia antigen in patients with internal diseases]. PMID- 4208006 TI - [Purification of bacteriophages on sepharose by gel chromatography]. PMID- 4208007 TI - [Ultrastructure and toxin formation of Cor. diphtheriae PW-8 cultured in the presence of penicillin]. PMID- 4208009 TI - Prophylactic antibiotics in elective abdominal hysterectomy. PMID- 4208008 TI - [Adsorptionless production of highly specific antibodies for the agglutination of certain serotypes of Shigella]. PMID- 4208010 TI - An integrated direct functional test of the adenohypophysis. PMID- 4208011 TI - The effect of force on craniofacial development. PMID- 4208012 TI - Separation of sulfur-containing components of transfer ribonucleic acid on Bio Gel P-2 and Sephadex G-10 columns. PMID- 4208013 TI - Automated determination of delta-aminolevulinic acid dehydratase activity in human erythrocytes. PMID- 4208014 TI - Semi-automated ninhydrin assay of Kjeldahl nitrogen. PMID- 4208015 TI - Intraocular injection of gentamicin. Single injection therapy of experimental bacterial endophthalmitis. PMID- 4208016 TI - Acid hydrolase deficiencies and abnormal glycoproteins in mucolipidosis. 3 (pseudo-Hurler polydystrophy). PMID- 4208017 TI - Proceedings: Population differences in meiotic recombination frequency between loci on chromosome 1. PMID- 4208018 TI - Proceedings: A family study suggesting genetic linkage of phosphopyruvate hydratse (enolase) to the Rh blood group system. PMID- 4208019 TI - Further evidence for cortical control over replication of the macronucleus and basal bodies in Stentor. PMID- 4208020 TI - Transplantation of nuclei into the polar plasm of Drosophila eggs. PMID- 4208021 TI - Effect of cytochalasin B on the evagination in vitro of leg imaginal discs. PMID- 4208022 TI - Pigment cell development in rhesus monkey eyes: an electron microscopic and histochemical study. PMID- 4208023 TI - Development of glycogen storage ability under cortisol control in primary cultures of rat fetal hepatocytes. PMID- 4208024 TI - Temperature-sensitive mutations in Drosophila melanogaster. 8. Temperature sensitive periods of the lethal and morphological phenotypes of selected combinations of notch-locus mutations. PMID- 4208025 TI - Pattern formation in imaginal discs of Drosophila melanogaster after irradiation of embryos and young larvae. PMID- 4208026 TI - The development of the imaginal abdomen of Drosophila melanogaster. PMID- 4208027 TI - Developmental properties of Shibire: a pleiotropic mutation affecting larval and adult locomotion and development. PMID- 4208028 TI - Partricin, an antifungal and antiprotozoal polyene antibiotic. PMID- 4208029 TI - Editorial: Coxsackie heart disease. PMID- 4208030 TI - Comparative study of Minocycline and Ampicillin in the treatment of urinary tract infections. PMID- 4208031 TI - Bioavailability of primidone in epileptic patients. PMID- 4208032 TI - Effect of long-term administration of Pindolol (LB-46, Visken) in essential circulatory hyperkinesis. A double-blind, cross-over study. PMID- 4208034 TI - The use of tissue adhesive (isobutyl cyanoacrylate) and topical steroid (0.1 percent dexamethasone) in experimental tympanoplasty. PMID- 4208033 TI - Studies on the surface of chick blastoderm cells. 3. Calcium binding to ionogenic sites. PMID- 4208035 TI - Effects of lead on the vestibular system: preliminary findings. PMID- 4208036 TI - Letter: When is glutamate neurotoxic? PMID- 4208037 TI - Policy options and the impact of national health insurance. PMID- 4208038 TI - Diabetic ketoacidosis. PMID- 4208039 TI - [A family with late spondyloepiphyseal dysplasia]. PMID- 4208040 TI - [A patient with "septic gonococcal dermatitis" syndrome]. PMID- 4208041 TI - The effect of experimental spasm on the CO2 response of cerebral bloodflow in primates. PMID- 4208042 TI - Autolysis in Listeria monocytogenes: effect of inhibitors of cell wall and protein synthesis. PMID- 4208043 TI - Hypertonic salt extraction of HL-A antigens: assessment of protease activity. PMID- 4208044 TI - Lipid and bone matrix calcification in vitro. PMID- 4208046 TI - Factors affecting autolysis of Neisseria gonorrhoeae. PMID- 4208045 TI - Growth inhibition and pyocin receptor properties of endotoxin from Pseudomonas aeruginosa. PMID- 4208047 TI - Sensitization of E. coli to the serum bactericidal system and to lysozyme by ethyleneglycoltetraacetic acid. PMID- 4208048 TI - Chemistry of hypothalamic releasing factors. PMID- 4208049 TI - Further observations on the structure and function of median eminence, with reference to the organization of RF-producing elements in the endocrine hypothalamus. PMID- 4208050 TI - The influence of the circadian thyrotropin rhythm on the thyrotropin response to thyrotropin-releasing hormone in normal subjects. PMID- 4208051 TI - Investigation of Bacillus subtilis mutants with changed capacity for formation of competent cells. PMID- 4208052 TI - Influence of vasopressin and topical bile salts on the gastric mucosal barrier of the subhuman primate. PMID- 4208053 TI - Total body potassium in surgical patients. PMID- 4208054 TI - [Letter: Changes in the oxygen affinity of hemoglobin in diabetics]. PMID- 4208055 TI - Affective state and thyrotropin and prolactin responses after repeated injections of thyrotropin-releasing hormone in depressed patients. PMID- 4208056 TI - [In vitro study of the effect of sodium chloride on the activity of 5 families of antibiotics on gram-negative bacilli]. PMID- 4208057 TI - [Morphology of bacteriophages of the genus Corynebacterium. Comparative aspects]. PMID- 4208058 TI - The relationships between nitrogen fixation and photosynthesis. The third Rubbo Memorial Oration, 1972. PMID- 4208059 TI - Concentrations of immunoglobulins and albumin in lymph collected from various regions of the body of the sheep. PMID- 4208060 TI - D-alanine carboxypeptidase from Streptococcus faecalis. PMID- 4208062 TI - Adsorption of bacteriophages specific for Pseudomonas aeruginosa R factors RP1 and R1822. PMID- 4208061 TI - Estimations of membrane potentials in Streptococcus faecalis by means of a fluorescent probe. PMID- 4208063 TI - Discrimination of isolation peep variants by squirrel monkeys. PMID- 4208064 TI - [Medullary carcinoma of the thyroid. Description of a case and critical review of Sipple's syndrome and of neuroectodermal tumoral associations]. PMID- 4208065 TI - Incidence of minor fractures in twisting injuries of the ankle. PMID- 4208066 TI - Medial dislocation of the ankle without fracture: a case report. PMID- 4208067 TI - Comparison of ophthalmic vehicles using fluorescein uptake technique. PMID- 4208068 TI - Cross reactions to antigens causing hypersensitivity pneumonitis. PMID- 4208069 TI - Erythema marginatum preceding hereditary angioedema. PMID- 4208070 TI - Factors influencing the frequency of mesosomes observed in fixed and unfixed cells of Streptococcus faecalis. AB - Mesosomes of Streptococcus faecalis (American Type Culture Collection 9790) were seen about 92% less frequently in freeze fractures of unfixed cells than in freeze fractures and sections of fixed cells. This difference in frequency was not related to any period of unbalanced macromolecular synthesis induced by chemical fixation. All measured synthetic processes (DNA, RNA, and protein synthesis, and glycerol incorporation) were halted with either osmium tetroxide (OS) or glutaraldehyde fixation. That fewer mesosomes were seen in freeze fractures of unfixed cells was probably due to the difficulty of observing cross fractured mesosomes in this organism in the unfixed state. Unfortunately, mesosomes probably preferentially cross fracture in the unfixed state and therefore are usually only observed, infrequently, in those cases where the freeze fracture follows the surface layer of a mesosomal membrane. However, the addition of glycerol to unfixed cells, especially in the chilled state, greatly increased the frequency of observation of cytoplasmic mesosomes in freeze fractures. It is thought that glycerol, like chemical fixation, increases the number of surface-fractured mesosomes, which in turn increases the frequency of mesosome observation. It was also observed that cellular autolysis occurring during OS fixation seemingly reduced the number of mesosomes observed in thin sections and freeze fractures of OS-fixed cells. PMID- 4208071 TI - Nafenopin-induced hepatic microbody (peroxisome) proliferation and catalase synthesis in rats and mice. Absence of sex difference in response. AB - Nafenopin (2-methyl-2[p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy]-propionic acid; Su-13437), a potent hypolipidemic compound, was administered in varying concentrations in ground Purina Chow to male and female rats, wild type (Cs(a) strain) mice and acatalasemic (Cs(b) strain) mice to determine the hepatic microbody proliferative and catalase-inducing effects. In all groups of animals, administration of nafenopin at dietary levels of 0.125% and 0.25% produced a significant and sustained increase in the number of peroxisomes. The hepatic microbody proliferation in both male and female rats and wild type Cs(a) strain mice treated with nafenopin was of the same magnitude and was associated with a two-fold increase in catalase activity and in the concentration of catalase protein. The increase in microbody population in acatalasemic mice, although not accompanied by increase in catalase activity, was associated with a twofold increase in the amount of catalase protein. The absence of sex difference in microbody proliferative response in nafenopin-treated rats and wild type mice is of particular significance, since ethyl-alpha-p-chlorophenoxyisobutyrate (CPIB) induced microbody proliferation and increase in catalase activity occurred only in males. Nafenopin can, therefore, be used as an inducer of microbody proliferation and of catalase synthesis in both sexes of rats and mice. The serum glycerol-glycerides were markedly lowered in all the animals given nafenopin, which paralleled the increase in liver catalase. All the above effects of nafenopin were fully reversed when the drug was withdrawn from the diet of male rats. During reversal, several microbody nucleoids were seen free in the hyaloplasm or in the dilated endoplasmic reticulum channels resulting from a rapid reduction in microbody matrix proteins after the withdrawal of nafenopin from the diet. Because of microbody proliferation and catalase induction with increasing number of hypolipidemic compounds, additional studies are necessary to determine the interrelationships of microbody proliferation, catalase induction, and hypolipidemia. PMID- 4208072 TI - Accumulation of replicative intermediates of mitochondrial DNA in Tetrahymena pyriformis grown in ethidium bromide. AB - The effect of growth of Tetrahymena pyriformis in ethidium bromide (EthBr) on the structure and synthesis of mitochondrial DNA (mtDNA) has been investigated. During the first 5 h of growth in EthBr, mtDNA synthesis is inhibited 95% or more. After 10-15 h, this block is partially released and large numbers of replicating molecules accumulate, indicating that inhibition by EthBr primarily affects the rate of chain growth and not the initiation of new rounds of replication. The accumulated molecules sediment more rapidly than normal Tetrahymena mtDNA and do not contain enough single-strand regions to distinguish them from normal Tetrahymena mtDNA when banded in buoyant CsCl or NaI gradients. Electron microscopy shows that the predominant species in this rapidly sedimenting DNA is a linear molecule containing one symmetrical double-stranded replication loop of varying size located at its center. No degradation of mtDNA from cells grown in EthBr was detected in alkaline velocity gradients. PMID- 4208073 TI - Autoradiographic localization of 13N after fixation of 13N-labeled nitrogen gas by a heterocyst-forming blue-green alga. AB - (13)N, generated by proton bombardment of (13)C powder, is rapidly and easily converted to (13)N-N(2), 0.01 atm pressure, ca. 10 mCi/ml, by automated Dumas combustion. (13)N fixed (as (13)N-N(2)) by algal filaments was localized by an autoradiographic technique which permits track autoradiography with isotopes having short half-lives. Our findings show directly that a minimum of about 25% of the N(2) fixation by intact, aerobically grown filaments of Anabaena cylindrica is carried out by the heterocysts. If all of the N(2) fixation takes place in the heterocysts, then the movement of nitrogen along the filaments can be characterized by a constant tau < ca. 5 s (cell(-2)). PMID- 4208075 TI - Vasopressin-induced changes in the toad urinary bladder epithelial surface. PMID- 4208076 TI - [Prevention and treatment of malaria. 1. Analysis of 73 cases of malaria in Japan]. PMID- 4208077 TI - [Prevention and treatment of malaria. 2. Preventive of malaria with folic acid (sulformethoxine-pyrimethamine or sulfamonomethoxine--pyrimethamine compounds)]. PMID- 4208074 TI - Action of cytochalasin D on cells of established lines. I. Early events. AB - HeLa, Vero, L, HEp2, and MDBK cells respond immediately to 0.2-0.5 microg/ml cytochalasin D (CD) with sustained contraction (contracture), loss of microvilli, expression of endoplasmic contents (zeiosis), nuclear protrusion, and extension of cytoplasmic processes. The development of these changes is depicted, and the dose-response patterns in these cell lines are described. MDBK is generally most resistant and HeLa most sensitive to these effects of CD. Cells in G(1) are most sensitive to CD; responsiveness decreases progressively during early S and is least in mid S through G(2). CD inhibits transport of [(14)C]deoxyglucose in HeLa by about 45% but has no significant effect on hexose uptake in Vero and MDBK; sugar transport is thus apparently unrelated to any morphologic effect of CD. Although spreading and attachment are impeded, CD does not decrease and may even enhance the adhesiveness of established monolayers. Contraction appears to be a primary early effect of CD, upon which other visible changes follow. It is prevented by some inhibitors of energy metabolism (deoxyglucose and dinitrophenol) and does not occur in glycerinated models without ATP. The possible bases of the contractile response to CD are discussed. Although direct or indirect action of CD on some microfilaments may occur, a generalized structural disruption of contractile filaments by CD is considered unlikely. PMID- 4208078 TI - [Isolation of trehalose non-fermentative Shigella sonnei]. PMID- 4208079 TI - Inhibition by carboxylic acids of an o-diphenol oxidase from Prunus avium fruits. PMID- 4208080 TI - The efficacy of systemic antibiotics in the treatment of granulating wounds. PMID- 4208081 TI - Cardiopulmonary changes with veno-arterial bypass in the hypoxic primate. PMID- 4208082 TI - Mitral valve replacement with the glutaraldehyde-preserved porcine heterograft. Clinical, hemodynamic, and pathological correlations. PMID- 4208083 TI - A new diagnostic test for acute myocardial infarction. The detection of myoglobinuria by radioimmunodiffusion assay. PMID- 4208084 TI - Cancer of the gastrointestinal Tract. D. Gastric cancer: treatment principles. PMID- 4208085 TI - [Significance of cord factor in tuberculosis]. PMID- 4208086 TI - [Morphology and clinical aspects of diverticulosis of the large intestine]. PMID- 4208087 TI - [Preparations for parenteral feeding (review of the literature)]. PMID- 4208088 TI - [Diverticulosis of the large intestine]. PMID- 4208089 TI - Studies on precipitating antibodies for Aspergillus flavus antigens in patients with proliferative diseases. PMID- 4208090 TI - [Discordant long-term therapy in chronic urinary tract infections]. PMID- 4208091 TI - [Epidemiology and biochemistry of risk factors of gout (author's transl)]. PMID- 4208092 TI - [Nephrolithiasis within the framework of internal medicine (author's transl)]. PMID- 4208093 TI - [Hyperiminoaciduria and disaminoaciduria in endemic (Balkan-)nephropathy (author's transl)]. PMID- 4208095 TI - [Multiple sclerosis patients as blood donors (author's transl)]. PMID- 4208094 TI - [Pathogenetic mechanism of the changing cell picture in myeloproliferative syndromes (author's transl)]. PMID- 4208096 TI - [Biosignals in the control of cell metabolism: a resonance hypothesis for carcinogenesis (author's transl)]. PMID- 4208097 TI - [Results of physical therapy of peripheral arterial circulatory disorders (author's transl)]. PMID- 4208098 TI - [Clinical experiences with SPN 40150 in hyperlipidemia and arteriosclerotic circulatory disturbances (author's transl)]. PMID- 4208099 TI - Comparative distemper vaccine titrations in ferrets and minks. PMID- 4208100 TI - [Study of the number of A, M and G, immunoglobulins in healthy children aged from 1 to 14 years]. PMID- 4208101 TI - Drugs which inhibit prostaglandin biosynthesis. PMID- 4208102 TI - Antibiotic-disinfection compatibility studies in solution used for dipping turkey hatching eggs. PMID- 4208103 TI - Some effects of DDT, toxaphene and polychlorinated biphenyl on thyroid function in Bobwhite quail. PMID- 4208104 TI - The effect of environmental temperature on parathyphoid infection in the neonatal chicken. PMID- 4208105 TI - [Rare case of Recklinghausen's disease]. PMID- 4208106 TI - [Value of routine radiography of the cranium in children with epilepsy]. PMID- 4208107 TI - Usefulness of methods of Australia antigen detection in viral hepatitis. PMID- 4208108 TI - [Effect of food dyes on reproduction of Listeria monocytogenes]. PMID- 4208110 TI - Some causal factors in autogrooming behaviour of adult Stump-Tailed Macaques (Macaca arctoides). PMID- 4208109 TI - [Histochemical examination of the cornea in a patient with Scheie's disease (presentation of a new family)]. PMID- 4208111 TI - The development of sociosexual behaviours in Japanese macaques Macaca fuscata. PMID- 4208112 TI - Triadic differentiation: an inhibitory process protecting pair bonds in baboons. PMID- 4208113 TI - Mercapturic acid biosynthesis: the separate identities of glutathione-S-aryl chloride transferase and ligandin. PMID- 4208114 TI - The combined effect of glycogen and ATP on the D to I conversion of glycogen synthetase. PMID- 4208115 TI - Generation of parvalbumin-like proteins from troponin. PMID- 4208116 TI - The effect of ionic strength on alkaline phosphatase. PMID- 4208117 TI - Carbonic anhydrase isoenzyme B in the erythrocytes of uremic subjects. PMID- 4208118 TI - Triiodothyronine radioimmunoassay: a study of the interactions of T3 with anti-T3 antisera and with thyroxine binding globulin in the presence of ANS (ammonium-8 anilino naphthalene-1-sulfonate). PMID- 4208119 TI - A study on the kinetics of pancreatic kallikrein with the substrate benzoyl arginine ethyl ester using a spectrophotometric assay. PMID- 4208120 TI - 3-Methoxy-4-hydroxyphenethylene glycol in plasma. PMID- 4208121 TI - Immunoglobulin A (IgA) with properties of both cryoglobulin and pyroglobulin. PMID- 4208122 TI - Separation of folates from antibiotics using triethylamino cellulose. PMID- 4208123 TI - [The role of changes in ion exchange in brain tissue in the mechanism of the central action of nitroglycerin]. PMID- 4208125 TI - [Electron microscopic findings in the liver in mucopolysaccharidosis]. PMID- 4208124 TI - [The effect of aflatoxins on animal cells in tissue culture (review of the literature)]. PMID- 4208126 TI - [Chlorpropamide, thiazides and congestive heart failure]. PMID- 4208127 TI - Immunoreactive growth hormone levels in mice with the obese-hyperglycemic syndrome (genotype obob). PMID- 4208128 TI - Thyrotrophin response to intravenous thyrotrophin-releasing hormone in patients with hepatic and renal disease. PMID- 4208129 TI - Localization of proteinase(s) near the cell surface of Streptococcus lactis. AB - Two criteria suggest that most of the proteinase of Streptococcus lactis is localized in the cell wall. (i) Intact cells possess proteinase activity when incubated with a high-molecular-weight substrate. (ii) Most of the cell-bound proteinase activity is released during spheroplast formation under conditions which result in the release of only 1% of the intracellular enzymes aldolase and glyceraldehyde-3-phosphate dehydrogenase. The solubilized cell wall, plasma membrane, and cytoplasm fractions contained 84, 0, and 16%, respectively, of the total proteinase activity with casein as substrate. The physiological role of a surface-bound proteinase in this organism is discussed. PMID- 4208130 TI - Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid absorption in Bacillus subtilis: ultrastructure of competent and noncompetent cells and cellular changes during development of competence. AB - By means of electron microscope autoradiography of component cultures of Bacillus subtilis exposed to [(3)H]thymidine-labeled transforming deoxyribonucleic acid competent and noncompetent cells can be distinguished. Competence is not limited to a specific phase of the cell division cycle. With serial section electron microscopy of competent and noncompetent cells, two types of mesosomal structures are observed: mesosomes connected to the plasma membrane only (plasma membrane mesosomes) and mesosomes which are additionally connected to the nuclear bodies (nuclear mesosomes). The two types show different cellular distributions. Especially the number of nuclear mesosomes is higher in competent than in noncompetent cells. This, and the observation that the increase and decrease of competence is correlated with both the number of cells carrying nuclear mesosomes and the number of nuclear mesosomes per cell, suggests that mesosomes are involved in the acquisition of competence. PMID- 4208131 TI - Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid absorption in Bacillus subtilis: localization of uptake and of transport of transforming deoxyribonucleic acid in competent cells. AB - With the aid of serial-section electron microscopy two types of mesosomes can be distinguished in cells of competent cultures of Bacillus subtilis: (i) mesosomes connected to the plasma membrane only (plasma membrane mesosomes) and (ii) mesosomes which extend from the plasma membrane into the nuclear bodies (nuclear mesosomes). Contrary to plasma membrane mesosomes, nuclear mesosomes are absent from the tip zones. Electron microscopic autoradiography of sections of Bacillus subtilis cells exposed to [(3)H]thymidine-labeled transforming deoxyribonucleic acid (DNA) for a short period of time shows that the DNA becomes associated with mesosomes. As a function of time the DNA migrates towards the nucleoids. Transport of DNA is completed within 15 to 60 min after termination of DNA uptake. During its migration the DNA continues to be associated with mesosomes, presumably with nuclear mesosomes. DNA initially associated with plasma membrane mesosomes of the tip zones is probably transported first towards the middle zones peripherally and from there towards the nucleoids. PMID- 4208132 TI - Novel ribonucleic acid species accumulated in the dark in the blue-green alga Anacystis nidulans. AB - In the dark, the obligately photoautotrophic blue-green alga Anacystis nidulans accumulates large relative amounts of two novel stable ribonucleic acid species (RNAs). These species are also made in illuminated cells but are unstable in them. When darkened cells are reilluminated, these RNAs are rapidly degraded; degradation is inhibited by chloramphenicol. Upon denaturation with heat or urea, one novel species (0.33 x 10(6) daltons) dissociates into two fragments that comigrate with the second novel species (0.16 x 10(6) daltons) on polyacrylamide gels. Both RNAs are associated with particles sedimenting between 30S and 50S through sucrose gradients and are removed from these particles at low magnesium concentration. The function(s) of these RNAs remains unknown. PMID- 4208133 TI - An unusual mutant affecting the frequency of organelle mutation. AB - A mutant of Euglena gracilis Z is described that spontaneously produces irreversibly bleached mutants at a high frequency. Bleaching only occurs during exponential growth under highly aerobic conditions. The kinetics for bleaching and growth of bleached and nonbleached cells suggest that mutation is induced by segregation of a cellular component that becomes limiting after several culture generations. The properties of spontaneous bleaching closely resemble the properties of induced organelle mutagenesis in E. gracilis and yeast. PMID- 4208134 TI - Outer membrane proteins of Escherichia coli. 3. Evidence that the major protein of Escherichia coli O111 outer membrane consists of four distinct polypeptide species. AB - Previous studies have shown that the outer membrane of Escherichia coli O111 gives a single, major, 42,000-dalton protein peak when analyzed by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis at neutral pH. Further studies have shown that this peak consists of more than a single polypeptide species, and on alkaline SDS-gel electrophoresis this single peak is resolved into three subcomponents designated as proteins 1, 2, and 3. By chromatography of solubilized, outer membrane protein on diethylaminoethyl-cellulose followed by chromatography on Sephadex G-200 in the presence of SDS, it was possible to separate the 42,000-dalton major protein into four distinct protein fractions. Comparison of cyanogen bromide peptides derived from these fractions indicated that they represented at least four distinct polypeptide species. Two of these proteins migrated as proteins 1 and 2 on alkaline gels. The other two proteins migrated as protein 3 on alkaline gels and cannot be separated by SDS polyacrylamide gel electrophoresis. In purified form, these major proteins do not contain bound lipopolysaccharide, phospholipid, or phosphate. These proteins may contain a small amount of carbohydrate, as evidenced by the labeling of these proteins by glucosamine, and to a lesser extent by glucose, under conditions where the metabolism of these sugars to amino acids and lipids is blocked. All of the proteins were labeled to the same extent by these sugars. Thus, it was concluded that there are at least four distinct polypeptide species with apparent molecular masses of about 42,000 daltons in the outer membrane of E. coli O111. PMID- 4208135 TI - Lipoteichoic acids from Streptococcus sanguis. AB - Two lipoteichoic acids, membrane (MLTA) and wall (WLTA), have been purified from Streptococcus sanguis by Sepharose and Ecteola-cellulose column chromatographies and concanavalin A-conjugated Sepharose affinity column chromatography. The teichoic acids were homogenous as judged by disc gel electrophoresis, column chromatography, and double diffusion tests. Both MLTA and WLTA consisted of glycerol, phosphate, glucose, and fatty acids in the ratios of 0.95:1:0.71:0.046 and 0.99:1:0.79:0.023, respectively. alpha-Glycerol-phosphate was obtained by the partial acid hydrolysis of the lipoteichoic acids suggesting that their backbone structure consists of the glycerol moieties linked by 1, 3-phosphodiester bonds. Both WLTA and MLTA form aggregates, perhaps due to micelle formation, in concentrated solution. The aggregate form of MLTA dissociates to a much greater extent than that of WLTA under similar conditions. PMID- 4208137 TI - Detachment and chemical characterization of the regularly arranged subunits from the surface of an Acinetobacter. AB - Acinetobacter sp. strain MJT/F5/199A carries an array of tetragonally arranged subunits on its outer surface. The subunits can be detached from isolated cell walls by incubation with 1 M urea or by washing with water after treatment with 10 mM ethylenediaminetetraacetic acid or ethyleneglycol-bis(beta aminoethylether)N,N'-tetraacetic acid. After removal of the urea, they reaggregate into the same ordered array at air-water interfaces in the presence of MgCl(2). The detached subunits were characterized as an acidic protein of molecular weight 65,000. They represent one-fifth of the total cell wall protein. PMID- 4208136 TI - Polyelectrolyte nature of bacterial teichoic acids. AB - Several physicochemical properties of the teichoic acid of Bacillus subtilis 168 have been determined. The teichoic acid partial specific volume was found to be 0.57 ml/g. The apparent weight-average molecular weight of the polymer was 24,800. Sedimentation was strongly dependent on solvent. The sedimentation coefficient of the teichoic acid was found to have a value of s(20.w) (0) = 1.90S. In dilute buffers and distilled water, the teichoic acid possessed a rigid rod or extended conformation. Salts induced a loss of secondary structure in the polymer, resulting in a random coil configuration. Salt-induced structural changes in the teichoic acid were determined by viscosities, ultraviolet difference spectra, and inhibition of precipitation with concanavalin A. Divalent cations such as Mg(2+) had little effect on the teichoic acid structure. The salt induced structural changes were reversible, as evidenced by return of the original properties upon dialysis of the teichoic acid against water. Sodium chloride inhibited the adsorption of bacteriophage o25 to B. subtilis cell walls. Teichoic acid conformation may have a significant influence on the physiology of bacteria. PMID- 4208138 TI - Penetration of Bdellovibrio bacteriovorus into host cells. AB - Electron microscopy reveals that, in Bdellovibrio infection, after the formation of a passage pore in the host cell wall, the differentiated parasite penetration pole is associated with the host protoplast. This firm contact persists throughout the parasite penetration and after this process is completed. In penetrated hosts this contact is also apparent by phase microscopy. The association between the walls of the parasite and the host at the passage pore, on the other hand, is transient. Bdellovibrio do not penetrate hosts whose protoplast and cell walls are separated by plasmolysis, or in which the membrane wall relationship is affected by low turgor pressure. It is concluded, therefore, that for penetration to occur it is essential that the host protoplast be within reach of the parasite, so that a firm contact can be established between them. A penetration mechanism is proposed that is effected by forces generated by fluxes of water and solutes due to structural changes in the infected host envelope. These forces cause a differential expansion of the host protoplast and cell wall and their separation from each other around the entry site, while the parasite remains firmly anchored to the host protoplast. Consequently, the parasite ends up enclosed in the expanded host periplasm. The actual entry, therefore, is a passive act of the parasite. PMID- 4208139 TI - Cell separation in blue-green bacteria. AB - Autolysin-like enzymes appear to be responsible for cell separation in Agmenellum quadruplicatum. Mutants that are impaired in cell separation and grow as chains exhibit reduced cell lytic activity. Lysozyme, extracted autolysin, and antibiotics that affect peptidoglycan synthesis phenotypically suppress chain formation. Various aspects of the regulation of the cell separation process were also examined. Studies involving antibiotic inhibitors of macromolecular synthesis and general growth inhibitors provided no evidence for the active regulation of the cell separation process during the latter portion of the division cycle. Evidence was obtained, however, for the partial restriction of peptidogly-can hydrolysis by unknown secondary modifications. The thin electron dense layer of peptidoglycan along the sides of cells was much more resistant to hydrolysis by egg-white lysozyme than was the septum between daughter cells. The middle portion of the septum was more sensitive than was the layer immediately adjacent to the cytoplasmic membrane. Under conditions that would not osmotically stabilize spheroplasts, lysozyme facilitates rapid cell separation in chain forming mutants with little leakage of cellular protein or loss of viability. PMID- 4208140 TI - Effect of temperature on the distribution of membrane particles in Streptococcus faecalis as seen by the freeze-fracture technique. AB - When cells of Streptococcus faecalis ATCC 9790 were incubated at temperatures above 10 C before being frozen for freeze-fracture, a random distribution of particles was observed on the outer fracture face of the freeze-cleaved cell membrane. However, when cells were incubated below 10 C before freezing, particleless patches were seen on this membrane surface. The size of the patches produced on chilling could be increased by centrifugation or by storing the chilled cells overnight at about 3 C. Patch formation appeared readily reversible, since the medium and large patches that formed on chilling could not be observed in cells warmed for 10 s at 25 C. However, during the transition from the patch to patchless state, smaller patches not seen in the chilled cells were observed. This suggested that the smaller patches might have been intermediate forms produced by the fragmentation of larger patches on warming. PMID- 4208142 TI - Unusual molecular properties of human IgG3 proteins due to an extended hinge region. PMID- 4208141 TI - The synthesis of polyribitol phosphate. II. On the mechanism of polyribitol phosphate polymerase. PMID- 4208143 TI - Symposium on reproduction of arthropods of medical and veterinary importance. I. Insect gametogenesis. PMID- 4208144 TI - Studies on the development of Rhodnius prolixus and the effects of its symbiote Nocardia rhodnii. PMID- 4208145 TI - Control of plague vectors on Peromyscus maniculatus by use of 2 percent carbaryl dust in bait stations. PMID- 4208146 TI - [Serum reactions in patients with chronic schistosomiasis japonica: test results of COP, Ouchterlony and immunoelectrophoresis]. PMID- 4208147 TI - [Laboratory animals for gerontlogical research]. PMID- 4208148 TI - [Allo- and heteroplasty in esophageal diverticula (preliminary report)]. PMID- 4208149 TI - Studies of the specificity of an antibody directed against probenecid. Investigations with probenecid analogs. PMID- 4208150 TI - Effects on drug metabolism of carbaryl and 1-naphthol in the mouse. PMID- 4208151 TI - [Radioisotope diagnosis of the neoplasms of soft tissues of the extremities and the body]. PMID- 4208152 TI - The glycogen synthase system in skeletal muscle of normal humans and patients with myotonic dystrophy: effect of glucose and insulin administration. PMID- 4208153 TI - A medium for rapid identification and enumeration of Aspergillus flavus and related organisms. PMID- 4208154 TI - [Attraction of Tarsonemus fusarii Cooreman 1941 by various fungi]. PMID- 4208155 TI - Fat-free parenteral alimentation of infants. PMID- 4208156 TI - Calorie supplementation and growth of pre-school children. PMID- 4208158 TI - Letter: Adrenal regulation of protein synthesis in protein malnutrition. PMID- 4208159 TI - [Crimean hemorrhagic fever antibodies in Hungary]. PMID- 4208160 TI - [Dermatoses and Bacillus pyocyaneus]. PMID- 4208157 TI - Metabolic effects of oral contraceptives in monkeys fed on adequate and low protein diets. PMID- 4208161 TI - [Ascites-free nutrient media in the diagnosis of gonorrhea by culture]. PMID- 4208162 TI - [Further study of the phenomenon of the loss by mammals of natural resistance to infection by the Newcastle disease virus]. PMID- 4208164 TI - WHO Expert Committee on Filariasis. Third report. PMID- 4208163 TI - [Study of the sensitivity of laboratory animals and cell cultures to LPV oncornavirus]. PMID- 4208165 TI - Food-borne disease: methods of sampling and examination in surveillance programmes. Report of a WHO study group. PMID- 4208166 TI - Analysis of spore and antibiotic markers in revertants from asporogenous and sporogenous non-producer mutants of Bacillus subtilis. PMID- 4208167 TI - Utilization of adenosine as a tool in studies on the regulation of liver glycogen biosynthesis. PMID- 4208168 TI - [Affinity of UDP glucuronyltransferase to chloramphenicol]. PMID- 4208169 TI - Metalloalkaline phosphatases from Bacillus subtilis: physicochemical and enzymatic properties. PMID- 4208171 TI - Studies on the mechanism of cell attachment to a substratum: evidence for three biochemically distinct processes. PMID- 4208170 TI - The physical and chemical properties of a chicken egg white glycoprotein purified by nondenaturing methodology. PMID- 4208172 TI - Fructose-1,6-diphosphate aldolase from Lactobacillus casei. I. Functional similarities with the rabbit muscle aldolase. PMID- 4208173 TI - Fructose-1,6-diphosphate aldolase from Lactobacillus casei. II. Multiple forms and their characteristics. PMID- 4208174 TI - Purification and properties of tyrosinases from Vibrio tyrosinaticus. PMID- 4208175 TI - The fate of 2-, 3-, and 4-chlorobiphenyl following intravenous administration to the thorny skate (Raja radiata) and the winter skate (Raja ocellata). PMID- 4208176 TI - Tissue modifications in monkeys as related to absorption, distribution, and excretion of polychlorinated biphenyls. PMID- 4208177 TI - Cholesteryl ester metabolism in liver and blood plasma of various animal species. PMID- 4208179 TI - Absorption of anticonvulsants after jejunoileal bypass. PMID- 4208178 TI - Bacteria isolated from imported salted duck eggs. PMID- 4208180 TI - Supratentorial tuberculoma: a case report and review. PMID- 4208181 TI - Letter: Treatment of angina pectoris. PMID- 4208182 TI - Letter: Treatment of angina pectoris. PMID- 4208183 TI - Renal tubular function in asthmatic children on long-term disodium cromoglycate. PMID- 4208184 TI - A study of the effect of betahistine on gastric acid secretion in man. PMID- 4208185 TI - [Isolated petit mal status epilepticus. A new epilepsy syndrome characterised by paroxysmal behavioural disturbances (author's transl)]. PMID- 4208186 TI - [The influence of various sulphonylurea derivatives on the oral glucose-tolerance tests in healthy subjects and obese and maturity-onset diabetics (author's transl)]. PMID- 4208187 TI - [Pharmacokinetics of carbenicillin in high dosage (author's transl)]. PMID- 4208188 TI - Neuronal activity in the chronic and acute epileptogenic focus. PMID- 4208189 TI - Trunk rigidity and limb hypotonia produced in squirrel monkeys by direct cholinergic stimulation of the globus pallidus. PMID- 4208190 TI - Cells of origin of the spinocervical tract in the monkey. PMID- 4208191 TI - Epileptic neurons during sleep and wakefulness. PMID- 4208192 TI - Effects of visual cortical lesions upon ambulatory and static localization of light in space. PMID- 4208193 TI - Rheumatoid factor in a series of 155 subjects with paraproteinaemia of the main immunoglobulin classes. PMID- 4208194 TI - Pre-institutionalization factors as predictors of adjustment to a long-term care facility. PMID- 4208195 TI - Isolation procedure for bacterial DNA based on gel permeation chromatography on a sepharose column. PMID- 4208197 TI - Selenium heterocycles. X. Synthesis and antibacterial activity of pyridyl-1,2,3 thiadiazoles and pyridyl-1,2,3-selenadiazoles. PMID- 4208196 TI - Interactions of sulfonylureas with plasma proteins. PMID- 4208198 TI - [A study of the dying off of blue-green algae in the dark]. PMID- 4208199 TI - Mild chymotryptic cleavage of human IgG and its major subclasses. PMID- 4208200 TI - Complex formation between monoclonal IgM and albumin. PMID- 4208201 TI - Erysipelas-like disease caused by Yersinia enterocolitica. PMID- 4208202 TI - Mumps meningoencephalitis in Stockholm. IV. Attempts at virus isolation from the urine in hospitalized mumps cases with or without diagnosed mumps meningoencephalitis. PMID- 4208203 TI - The prognosis of chronic staphylococcal osteomyelitis after long-term antibiotic treatment. PMID- 4208204 TI - In vitro sensitivity of isolates of Pseudomonas aeruginosa to carbenicillin, gentamicin, tobramycin, and some other antibiotics. PMID- 4208205 TI - The isolation of strains of rickettsiae of the spotted fever group in Israel and their differentiation from other members of the group by immunofluorescence methods. PMID- 4208206 TI - Candida albicans antibodies in candidiasis. PMID- 4208207 TI - Concentration of penicillin and tetracycline in maxillary sinus secretion after a single dose. PMID- 4208208 TI - Trimethoprim in the treatment and long-term control of urinary tract infection. PMID- 4208209 TI - Orthopaedic infections treated at an infectious disease hospital. PMID- 4208210 TI - An evaluation of the genetic structure of a Drosophila melanogaster population with respect to the characteristic radius incompletus. I. Change in characteristic caused by selection. PMID- 4208211 TI - The effect of boron on the nucleolus, chromocenter, and chromosomes of Drosophila melanogaster salivary gland cells. PMID- 4208212 TI - Investigation of the operon of riboflavin biosynthesis in Bacillus subtilis. 3. Production and properties of mutants with a complex regulator genotype. PMID- 4208213 TI - [Radioimmunologic determination of serum glibenclamide]. PMID- 4208214 TI - [Combined intravenous glucose-glibenclamide load as test for prediction of success of oral longtime therapy of adult diabetes with glibenclamide]. PMID- 4208215 TI - [Insulin secretion following combined administration of glucose and different sulfonylurea compounds in equipotential doses in metabolically healthy persons]. PMID- 4208217 TI - [Different courses of Waldenstrom's macroglobulinemia]. PMID- 4208216 TI - [Longtime effect of blood sugar decreasing sulfonamides on glucose tolerance and insulin secretion in adult diabetic patients]. PMID- 4208218 TI - [Monoclonal cryoglobulin with antinuclear activity and S-chain fragment in Waldenstrom's disease]. PMID- 4208219 TI - [Error possibilities in differentiation of blood pictures from EDTA blood]. PMID- 4208220 TI - [Biochemical studies of glycogen metabolism of human blood lymphocytes]. PMID- 4208221 TI - [Immunoglobulins in acute hepatitis]. PMID- 4208223 TI - [Pathogenesis of listeriosis in sheep]. PMID- 4208222 TI - [Immunologic and electron microscopic findings after formation of liver autoantibodies]. PMID- 4208224 TI - Ectopic atrial rhythms in the primate. PMID- 4208225 TI - [Conservation and prolonged survival of spermatozoa in the genital tract of female vertebrates]. PMID- 4208226 TI - The molecular basis of contractility. I. PMID- 4208227 TI - Effect of hemorrhagic shock on capillary transport in dog skeletal muscle. PMID- 4208228 TI - Studies on the antithrombotic effect of dextran effect on platelet 5 hydroxytryptamine and adenine nucleotides. PMID- 4208229 TI - Study on the acute effects of O-(beta-hydroxyethyl)-rutoside (HR) on the increased muscle capillary permeability in long-term diabetics. PMID- 4208230 TI - Betahistine HCL antagonism upon neural influence on microcirculation. PMID- 4208231 TI - Effects of O-(beta-hydroxyethyl)-rutosides (HR) and indomethacin on transcapillary macromolecular transport and prostaglandins following scalding injury. PMID- 4208232 TI - Vascular and extravascular spaces in two transplantable tumors of the rat. PMID- 4208233 TI - Characterization of rat liver lysosomal cathepsin A1. PMID- 4208234 TI - Purification and properties of cathepsin D from human erythrocytes. PMID- 4208236 TI - Purification and properties of a nitrate reductase-inactivating enzyme. PMID- 4208235 TI - Studies on the lipase of Chromobacterium viscosum. 3. Purification of a low molecular weight lipase and its enzymatic properties. PMID- 4208237 TI - Interaction of bovine carbonic anhydrase with acetate ions. PMID- 4208238 TI - NMR studies of the two binding sites of acetate ions to manganese(II) carbonic anhydrase. PMID- 4208239 TI - The identification of the forms of folate found in the liver, kidney and intestine of the monkey and their biosynthesis from exogenous pteroylglutamate (folic acid). PMID- 4208240 TI - Antibodies to indolealkylamines: serotonin and melatonin. PMID- 4208241 TI - The transfer of glucose to steroids by sheep liver microsomes. PMID- 4208242 TI - The 4.5 Angstrom resolution structure of a bacterial serine protease from Streptomyces griseus. PMID- 4208243 TI - Biosynthesis of the diguanosine nucleotides. I. Purification and properties of an enzyme from yolk platelets of brine shrimp embryos. PMID- 4208244 TI - The effect of the amount of nucleic acid load on hydroxylapatite chromatography. PMID- 4208245 TI - A rapid quantitative microtitration of Pseudomonas aeruginosa antibody. PMID- 4208246 TI - Serological survey of Pseudomonas aeruginosa strains isolated from patients in Canadian hospitals. PMID- 4208247 TI - Glycerol ester hydrolase, lipase, of Myxococcus xanthus FB. PMID- 4208248 TI - New data on the taxonomy of the Brazilian marmosets of the genus Callithrix Erxleben, 1777. PMID- 4208249 TI - Heart rate (radiotelemetrical registration) in macaques and baboons according to dominant-submissive rank in a group. PMID- 4208250 TI - Maternal-fetal weight relationships in primates. PMID- 4208251 TI - The effect of corpora allata on the plasma membrane of the symbiotic bacteria of the oocyte surface of Periplaneta americana L. PMID- 4208252 TI - [Experiences from an outbreak of Salmonella paratyphi B]. PMID- 4208253 TI - [Emergency care of diabetic coma in city hospitals]. PMID- 4208254 TI - [Exotoxins and enzyme systems]. PMID- 4208255 TI - [Study of several strains of neisseria gonorrhoeae isolated with the selective medium for gonococcus]. PMID- 4208257 TI - [Editorial: Hypertension. Introduction]. PMID- 4208256 TI - Influence of growth conditions on the composition of some streptococcal amino acid pools. PMID- 4208258 TI - [The neurology and neuropathology of hypertension (author's transl)]. PMID- 4208259 TI - [Fundus hypertonicus: mirror of the kidney or the brain? (author's transl)]. PMID- 4208260 TI - [Hypertension and oral contraception]. PMID- 4208261 TI - [Psychosomatic and psychiatric aspects of hypertension (author's transl)]. PMID- 4208262 TI - [Differential diagnosis and pharmacotherapy of hypertension (author's transl)]. PMID- 4208263 TI - [Surgery in hypertension (author's transl)]. PMID- 4208264 TI - [Hypertension and driving ability]. PMID- 4208265 TI - [Electroclinical correlations in localized traumatic meningocerebral dilaceration]. PMID- 4208266 TI - [Studies of cross protection between sera and venoms of the most common species of Mexican snakes]. PMID- 4208267 TI - [Use of equine albumin in pretransfusional tests]. PMID- 4208268 TI - Spinal cord blood flow in the rhesus monkey by the hydrogen clearance method. PMID- 4208269 TI - Studies on dentin. I. Mantle dentin. PMID- 4208270 TI - Studies on plasma somatomedin activity in different animal species. PMID- 4208271 TI - Parathyroid hormone secretion in disorders of calcium metabolism studied by means of EDTA. PMID- 4208272 TI - The changing scene in public health: Delta Omega Lecture. PMID- 4208273 TI - Cross-resistance and collateral susceptibility to antifolic antimalarial compounds. AB - Series of strains of Streptococcus faecium ATCC 8043, Lactobacillus casei ATCC 7469, and Pediococcus cerevisiae ATCC 8081 with increasing resistance to the active antifolate antimalarial drugs chlorguanide triazine (CGT), pyrimethamine (PM), and trimethoprim (TMP) were isolated. These mutant strains, stable for at least 3 to 5 years, were examined for cross-resistance and collateral susceptibility to the above compounds and to methotrexate (MTX). Generally, they exhibited cross-resistance to all four compounds, but resistance of a strain to one compound did not predict accurately its resistance to another drug. Unexpectedly, L. casei resistant to CGT exhibited collateral susceptibility to MTX, TMP, and PM varying from 5- to 20-fold. P. cerevisiae developed resistance to CGT readily but maintained its susceptibility to PM and TMP after prolonged exposure to these compounds. Resistance to these antimalarial antifolates was accompanied by only low-grade cross-resistance to MTX, a representative antileukemic antifolate agent. PMID- 4208274 TI - Mechanisms and spectrum of streptomycin resistance in a natural population of Pseudomonas aeruginosa. AB - A survey of 200 strains of Pseudomonas aeruginosa isolated from clinical specimens was made in an attempt to correlate the spectrum of their streptomycin resistance and the mechanism of resistance. The strains can be classified into three groups, according to their level of resistance to streptomycin: susceptible, low-level resistant, and high-level resistant strains. The mechanism of resistance of high-level resistant strains is either an R factor-mediated inactivation of streptomycin by phosphorylation or streptomycin-resistant ribosomes. However, such high-level resistant strains comprised less than 10% of the total strains isolated; the majority of the strains resistant to streptomycin were of low-level resistance. The latter are associated with a diminished uptake of streptomycin, and no evidence of streptomycin inactivation, resistant ribosomes, or R factors could be detected. The most probable explanation of low level resistance is reduced permeability to streptomycin. Modification of the growth medium used in uptake studies simultaneously affected strongly both streptomycin incorporation and the minimal inhibitory concentration of streptomycin. PMID- 4208275 TI - Comparison of tobramycin, gentamicin, colistin, and carbenicillin in Pseudomonas sepsis in monkeys. AB - Intravenous inoculation of 3.4 x 10(10) to 7.4 x 10(10)Pseudomonas aeruginosa organisms into rhesus monkeys 4 days after intravenous or intratracheal inoculation of 2.0 to 2.5 mg of vincristine sulfate resulted in fatal sepsis in eight of nine monkeys. After intramuscular administration, in two equal doses, of 5 mg of tobramycin, gentamicin, and colistin per kg per day beginning 16 hr after challenge, 4 of 11, 4 of 11, and 3 of 10 monkeys died, respectively. Administration of daily doses of 100 to 400 mg of carbenicillin per kg was followed by death in 5 of 12. Duration of illness in the surviving monkeys in each therapy group was similar. Under the conditions of this study, prior administration of vincristine sulfate resulted in a decrease in leukocytes and enhanced susceptibility to Pseudomonas infection. Using this model for studies of comparative efficacy of antibiotics, we observed comparable results after treatment with tobramycin, gentamicin, colistin, and carbenicillin. PMID- 4208277 TI - Inhibition of chlorination in Streptomyces aureofaciens by nitriles and related compounds. AB - A number of nitriles and cyano compounds inhibited chlorination by Streptomyces aureofaciens. In most cases, this inhibition was enhanced by bromide. Methylene blue and p-amino-propiophenone reversed the inhibition to some extent. PMID- 4208276 TI - Comparison of colistin-carbenicillin, colistin, and carbenicillin in Pseudomonas sepsis in monkeys. AB - Intravenous inoculation of 6.2 x 10(10) to 6.7 x 10(10)Pseudomonas aeruginosa organisms into rhesus monkeys 5 days after intratracheal inoculation of 2.0 to 2.5 mg of vincristine sulfate resulted in fatal sepsis in 8 of 10 untreated monkeys. When similarly infected monkeys were treated intramuscularly with 2.5 mg of colistin or 50 mg of carbenicillin per kg per day, all three monkeys in each treatment group survived; one of three monkeys receiving both antibiotics at the above doses died. Six of seven monkeys treated with 1.25 mg of colistin per kg per day and three of seven treated with 25 mg of carbenicillin per kg per day died; four of nine monkeys receiving both antibiotics at these doses died. A combination of the data obtained at both dose levels tested shows that 6 of 10, 3 of 10, and 5 of 12 monkeys, respectively, died after treatment with colistin, carbenicillin, and the colistin-carbenicillin combination. Antibacterial activity of serum from both infected and normal monkeys was not appreciably different when the two antibiotics were given singly or in combination. Under the conditions of this study and with the doses employed, the response of monkeys treated with the antibiotic combination did not differ significantly from that of monkeys treated with a single agent. PMID- 4208278 TI - Biliary excretion of a new semisynthetic cephalosporin, cephacetrile. AB - The biliary excretion of a new derivative of cephalosporin, cephacetrile (CIBA 36 278 Ba), was studied (i) in the isolated perfused rabbit liver, (ii) in humans with a duodenal tube, and (iii) in patients after cholecystectomy with a Kehr's drain in the common bile duct. The biliary excretion of the antibiotic was very low in the perfused liver, and no antibiotic activity was found in liver tissue at the end of the experiment. This observation, together with the finding of a rapid decline of the antibiotic concentration in the circulating blood serum, favors the assumption that a metabolic transformation of CIBA 36 278 Ba in liver tissue takes place. In humans, the antibiotic concentration was found to be low both in the duodenal juice and in the bile obtained by external drainage. The biliary concentrations found in these subjects seem to be inferior to those required for the inhibition of the common bacteria of biliary infections. In renal failure, however, the biliary excretion of CIBA 36 278 Ba increased considerably. PMID- 4208279 TI - A9145, a new adenine-containing antifungal antibiotic: fermentation. AB - A9145 is a basic, water-soluble, antifungal antibiotic which is produced in a complex organic medium by Streptomyces griseolus. The metabolite has a molecular weight of 510, and contains adenine as well as sugar hydroxyl and amino groups. Although glucose, fructose, glucose polymers, and some long-chain fatty acid methyl esters supported biosynthesis, oils were superior, with cottonseed oil being preferred. Several ions and salts, especially Co(2+), PO(4) (3-), and CaCO(3), were stimulatory. Adenine, nucleosides, and some amino acids increased the accumulation of A9145 in shaken-flask fermentors. Enrichment of the culture medium with tyrosine afforded maximal enhancement of antibiotic production in both flask and tank fermentors. Control of the dissolved O(2) level was also critical, the optimal concentration being 3 x 10(-2) to 4.5 x 10(-2) mumole of O(2)/ml. Optimization of various fermentation parameters increased antibiotic titers approximately 135-fold in shaken flask fermentors and 225-fold in stirred vessels. PMID- 4208280 TI - Cation reversal of inhibition of growth by valinomycin in Streptococcus pyogenes and Clostridium sporogenes. AB - Study of the antimicrobial spectrum of valinomycin revealed that, in addition to the gram-positive bacteria reported in literature, Streptococcus pyogenes and Clostridium sporogenes are also susceptible to this antibiotic. The minimal inhibitory concentrations (MIC) of the antibiotic for S. pyogenes grown aerobically and anaerobically did not differ markedly, negating the hypothesis that oxidative phosphorylation is involved in the mechanism of action of this antibiotic. This conclusion is further strengthened by the inhibition of growth of C. sporogenes, an obligate anaerobe. In a medium with a low K(+) concentration, the MIC for S. pyogenes was 0.02 mug/ml, the lowest ever recorded for this antibiotic. The inhibition of growth of S. pyogenes and C. sporogenes was readily reversed by addition of K(+) to the medium, indicating a compensation for net efflux of K(+) from the cells when the transmembrane potential reached equilibrium. In contrast to these bacteria, Bacillus subtilis was less susceptible to the antibiotic when the potassium concentration of the medium was low. The addition of potassium in the presence of valinomycin increased the inhibition of growth, which appears to result from dissipation of metabolic energy as in the mitochondrial system. PMID- 4208281 TI - In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses. AB - Virazole (1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) is a highly soluble new synthetic nucleoside having significant, reproducible activity against a broad spectrum of deoxyribonucleic acid and ribonucleic acid viruses in vitro. The drug inhibited viral cytopathogenic effects in monolayers of cells infected for 3 days with type 3 adeno, types 1 and 2 herpes, myxoma, cytomegalo, vaccinia, infectious bovine rhinotracheitis, types 1A, 2, 8, 13, and 56 rhino, types 1 and 3 parainfluenza, vesicular stomatitis, subacute sclerosing panencephalitis, Semliki Forest, Newcastle disease, and measles viruses. Hemagglutinin production by influenza A(2), influenza B, and type 1 parainfluenza viruses in chicken embryo cells was reduced by Virazole treatment. Recoverable intra- and extracellular virus titers were reduced by the drug in experiments with type 1 herpes, vaccinia, type 3 parainfluenza, and vesicular stomatitis viruses. Plaque formation by type 1 herpesvirus was also inhibited by exposure of the infected cells to Virazole. Pretreatment of cells with the compound, followed by its removal before addition of type 1 herpesvirus, severely lessened the antiviral activity; the compound was still moderately effective in reducing the viral effects on the cells when added as long as 22 hr after the virus. Parallel experiments, in which the antiviral activity of a number of known active drugs was compared, indicated Virazole to have at least a comparable degree of activity, and it was also active against a wider variety of viruses than any of these known active materials. The CCED(50) of Virazole to chicken embryo cells was approximately 1,000 mug/ml, although concentrations as low as 10 mug/ml caused slight (15%) inhibition in total cellular protein after 72 hr of incubation. PMID- 4208282 TI - Amoxicillin, a new penicillin antibiotic. AB - Amoxicillin (alpha-amino-p-hydroxybenzyl penicillin, BRL 2333) is a new semisynthetic penicillin which is structurally similar to ampicillin, but which is better absorbed and yields higher concentrations in serum and urine. The in vitro susceptibility of 145 strains of Enterobacteriaceae and 30 isolates of Pseudomonas aeruginosa was determined against various concentrations of amoxicillin and ampicillin in agar. In addition, inhibitory zones around discs containing 10 mug of amoxicillin were measured and compared with results of agar dilution studies. The drug also was evaluated in the treatment of 38 patients with bacteriuria, who received doses of either 750 mg or 1 g/day for 10 days. In vitro, amoxicillin was comparable in activity to ampicillin; most isolates of Escherichia coli and Proteus mirabilis were inhibited by 10 mug or less/ml, whereas the majority of strains of Enterobacter, Klebsiella, indole-positive Proteus species, and Pseudomonas grew in concentrations greater than 50 mug/ml. Clinically, amoxicillin was effective in eradicating bacteriuria due to susceptible organisms and was very well tolerated. For practical purposes, however, amoxicillin performed no better than a host of other drugs presently available for the treatment of acute, uncomplicated bacteriuria. PMID- 4208283 TI - Comparison of gentamicin, carbenicillin and gentamicin, and carbenicillin in Pseudomonas sepsis in monkeys. AB - Intravenous inoculation of 6.0 x 10(10)Pseudomonas aeruginosa organisms into rhesus monkeys 4 days after intratracheal inoculation of 2.5 mg of vincristine sulfate resulted in fatal sepsis in all of three untreated control monkeys. After intramuscular administration of either 2.5 mg of gentamicin or 50 mg of carbenicillin per kg per day, three of four monkeys in each group survived. When both antibiotics were given at the same dose but in separate sites, six of eight monkeys survived. Antibacterial activity of serum from infected monkeys or normal monkeys was not appreciably different when the two antibiotics were combined. Under the conditions of this study, there was no apparent difference in response of monkeys treated either with gentamicin or carbenicillin alone or with the combination of the two antibiotics. PMID- 4208284 TI - Molecular characterization of the R factors implicated in the carbenicillin resistance of a sequence of Pseudomonas aeruginosa strains isolated from burns. AB - An outbreak of R-factor-mediated carbenicillin resistance in Pseudomonas aeruginosa in burned patients in March 1969 was followed by a second outbreak 6 months later. No R-factor-carrying P. aeruginosa strains were detected in the intervening period but R-factor-determined lactamase was commonly encountered, particularly in Klebsiella aerogenes strains. A comparison of the molecular properties of the R factors in pseudomonads from the first and second phases with those in the Klebsiella strains from the intervening period showed them to be very closely related. A single R-factor type therefore may have been maintained in the Burns Unit between the two Pseudomonas outbreaks as a plasmid conferring resistance to ampicillin in K. aerogenes. PMID- 4208285 TI - Discrepancy between carbenicillin and ampicillin activities against enterococci and Listeria. AB - For infections of the newborn, carbenicillin has theoretical advantages over ampicillin, when given with an aminoglycoside, because of its activity against Pseudomonas and many indole-positive Proteus strains. Agar and broth dilution susceptibility studies demonstrated comparable activities of carbenicillin and ampicillin against coliform organisms but greater resistance of enterococci and Listeria to carbenicillin. However, the significance of the higher inhibitory concentrations is questionable because many serum specimens containing concentrations of carbenicillin lower than the minimal bactericidal values for Listeria and enterococcus strains had demonstrable in vitro bactericidal activity. Carbenicillin and gentamicin combinations had greater antibacterial activities than either drug alone against all enterococci tested and against 50% of Listeria strains. The questions of efficacy raised by contradictory in vitro data may be answered by clinical studies of carbenicillin and gentamicin in infections of the newborn. PMID- 4208287 TI - Interaction between deoxyribonucliec acid and distamycin A studied by transformation in Bacillus subtilis. AB - Distamycin A inhibits deoxyribonucleic acid (DNA)-mediated transformation and transfection in Bacillus subtilis at doses with little or no antibacterial effect. The inhibition of transformation parallels the inhibition of DNA uptake; further-more, during the transformation process, donor DNA molecules become distamycin and deoxyribonuclease resistant at the same time. This demonstrates that the drug acts by inhibiting DNA uptake. Although the drug is known to bind DNA, the inhibition is not related to affinity of the drug for DNA. This is shown by the lack of dependence of the extent of inhibition on DNA concentration, whereas the degree of inhibition depends upon cell concentration. Supporting this view is the fact that transformation by single-stranded DNA was also inhibited, even though the drug does not bind to denatured DNA. Distamycin A probably interferes with transformation by competing with DNA for some unknown bacterial component involved in transport of DNA into the cell. PMID- 4208286 TI - Mode of action illudin S. AB - The effect of the antitumor antibiotic illudin S on bacterial macromolecular synthesis was investigated. Illudin S was found to be inhibitory to in vivo deoxyribonucleic acid (DNA) synthesis from thymidine. Ribonucleic acid (RNA) synthesis was inhibited only at a concentration of illudin S 10 times that which inhibited DNA synthesis. The rate of protein synthesis remained the same except for a brief initial inhibition. When thymidine triphosphate was used for in vitro DNA synthesis, inhibition by illudin S did not occur, as tested with partially purified DNA polymerase II from Escherichia coli pol A(1) (-), with E. coli DNA dependent RNA polymerase, with E. coli pol A(1) (-) spheroplasts, and with frozen and thawed Bacillus subtilis cells. A protein fraction isolated from B. subtilis capable of forming thymidine mono-, di-, and triphosphates from thymidine was not inhibited by illudin S. Furthermore, (14)C-illudin S taken up by B. subtilis cells was reisolated unchanged, making an intracellular activation of illudin S unlikely. Therefore, an attractive hypothesis is that illudin S inhibits DNA synthesis from thymidine which does not proceed through deoxyribonucleoside triphosphates, the generally accepted substrates for DNA synthesis. PMID- 4208288 TI - Susceptibility of whole cells and spheroplasts of Pseudomonas aeruginosa to actinomycin D. AB - Cells of Pseudomonas aeruginosa suspended in 0.2 M Mg(2+), 20% sucrose, 0.01 M tris(hydroxymethyl)aminomethane, or water partially release lipopolysaccharide. The release of alkaline phosphatase from the periplasmic space and the ability to form spheroplasts on lysozyme treatment is directly related to the lipopolysaccharide released during treatment with 0.2 M Mg(2+), 20% sucrose, or other agents. The synthesis of ribonucleic acid (RNA) by intact cells, magnesium lysozyme spheroplasts, or 20% sucrose-lysozyme spheroplasts is not sensitive to actinomycin D, whereas RNA synthesis by intact cells or spheroplasts in the presence of ethylene-diaminetetraacetic acid (EDTA) is sensitive to actinomycin D. EDTA alone has an inhibitory effect on RNA synthesis by whole cell, by magnesium-lysozyme spheroplasts, and by 20% sucrose-lysozyme spheroplasts. The experimental data indicate that, although the cell wall is damaged by 0.2 M Mg(2+) or 20% sucrose treatment in the presence of lysozyme, the treated cells or spheroplasts are still resistant to actinomycin D. These results suggest that the cytoplasmic membrane should be considered as the final and determinative barrier to this antibiotic in this organism. PMID- 4208289 TI - Pharmacokinetic studies of tobramycin and gentamicin. AB - Broth dilution susceptibility tests of 100 isolates of Pseudomonas aeruginosa and 101 isolates of Staphylococcus aureus against tobramycin (formerly nebramycin factor 6) and gentamicin showed that tobramycin was more effective against P. aeruginosa and less effective against S. aureus. The minimal inhibitory concentration of tobramycin against the Pseudomonas sp. isolates that required 5 mug of gentamicin per ml for inhibition ranged from 0.63 to 0.31 mug/ml. Peak concentrations in the blood of 10 healthy adults after intramuscular injection of 80 and 40 mg of tobramycin averaged 3.7 +/- 0.62 and 2.4 +/- 0.27 mug/ml, and declined to 0.56 +/- 0.05 and 0.26 +/- 0.02 mug/ml, respectively, after 6 h. The urine recovery averaged 60%. The half-life was 1.6 h. During continuous intravenous infusion of tobramycin and gentamicin (infusion rate 6.6 mg per h), blood levels at steady state were 0.94 +/- 0.10 and 1.04 +/- 0.06 mug/ml, respectively. For both antibiotics, the calculated distribution volume ranged from 15 to 17 liters. The renal clearance to tobramycin averaged 76% and that of gentamicin averaged 85% of the total clearance, indicating that the drugs are primarily eliminated by the kidneys. The present results suggest that tobramycin may be more successful in the treatment of Pseudomonas infections than gentamicin at the same dosage (80 mg intramuscularly three to four times daily). PMID- 4208291 TI - Increased susceptibility of Neisseria gonorrhoea from a rural area. AB - The in vitro susceptibility of 18 to 24 isolates of Neisseria gonorrhoea were tested against 12 different antimicrobial agents. These isolates represent all of the gonococcal organisms which had been isolated by the bacteriology laboratory of the Vermont State Department of Health from 1 March to 31 July 1972 and originated from patients cultured in Vermont. These isolates were considerably more susceptible to penicillin G and tetracycline than are current isolates from elsewhere in the United States and Canada. Possible explanations for this difference are discussed. PMID- 4208290 TI - Pharmacokinetics of the aminoglycoside antibiotic tobramycin in humans. AB - The pharmacokinetics, distribution, and plasma and renal clearance of a new aminoglycoside antibiotic, tobramycin, was studied in the treatment of 18 elderly male patients (average age, 69 years) with urinary tract infections. Ten of these patients had normal renal function and eight had impaired renal function of various degrees. After administration of 1 mg of tobramycin/kg of body weight every 6 to 8 h (two to three times the half-life), urine concentrations were found to be sufficient in the treatment of urinary tract infections caused by susceptible organisms. The renal clearance of tobramycin during constant intravenous infusion was also studied in eight patients. Good correlation was found between the patients serum creatinine and the half-life of tobramycin. The half-life of tobramycin in patients with normal renal function (serum creatine [Formula: see text] to 1.5 mg/100) was on the average 3 h. For practical purposes, therefore, the dosage of tobramycin in the treatment of urinary tract infections should be 1 mg/kg of body weight every 6 to 8 h in patients with normal renal function. For patients with impaired renal function, the dosage interval is calculated by multiplying the patients' serum creatinine by six. If the dosage intervals are kept unchanged, the dosage must be divided by the patients' serum creatinine. The initial loading dose should always be 1 mg/kg. The total renal clearance of tobramycin (92% of the glomerular filtration rate) was not influenced by the administration of probenecid, which indicates that tobramycin is excreted only by glomerular filtration. PMID- 4208292 TI - Penicillin-tobramycin synergism against enterococci: a comparison with penicillin and gentamicin. AB - Combinations of penicillin plus tobramycin have been compared with penicillin plus gentamicin against 27 strains of enterococci isolated from blood cultures. Penicillin plus gentamicin was synergistic against all strains. The combination of penicillin plus tobramycin was equally effective against strains of Streptococcus facalis, but was ineffective against all four strains of S. faecium tested. PMID- 4208293 TI - Chloroquine-resistant Plasmodium falciparum: difference in the handling of 14C amodiaquin and 14C-chloroquine. AB - (14)C-amodiaquin and (14)C-chloroquine were used to study drug binding by preparations of owl monkey erythrocytes infected either with a chloroquine susceptible (CS) or with a chloroquine-resistant (CR) strain of P. falciparum. Both of these drugs are derivatives of 4-aminoquinoline, but they differ in their side chains, and there are differences in the way they are handled by preparations of erythrocytes infected with malaria parasites. Although the apparent association constant for the binding of either drug is approximately 10(7) mol(-1), two to three times more radioactivity was bound from (14)C amodiaquin than from (14)C-chloroquine. Furthermore, there was no apparent difference between CS and CR parasites with respect to (14)C-amodiaquin binding, whereas erythrocytes infected with CR parasites have a deficiency of (14)C chloroquine binding. This difference in the handling of amodiaquin probably accounts for its superiority in the treatment of the owl monkey and of humans infected with CR P. falciparum. PMID- 4208294 TI - Silver sulfadiazine: effect on the ultrastructure of Pseudomonas aeruginosa. AB - Pseudomonas aeruginosa exposed to silver sulfadiazine (AgSu) were examined in an electron microscope. The treated cells were distorted in shape, and structures (blebs) protruded from the cell surface. These "blebs" appeared to arise from the cell wall. A strain of P. aeruginosa resistant to AgSu did not display these changes. Upon exposure of P. aeruginosa to silver nitrate, none of these changes was seen; rather, such cells are characterized by large, central aggregations of nuclear material. The results are consistent with previous findings which suggested that AgSu acted at the cell surface. PMID- 4208295 TI - Characteristics of R931 and other Pseudomonas aeruginosa R factors. AB - R factors were detected in 3.3% of 233 hospital isolates of Pseudomonas aeruginosa using P. aeruginosa recipients in conjugations. Transferred markers included streptomycin, tetracycline, and sulfonamide resistance. Gentamicin resistance was transferred from two strains previously shown to acetylate gentamicin. A group of R factors exemplified by R931 were characterized by failure to transfer to Escherichia coli recipients. Such R factors formed a single compatibility group when examined in a P. aeruginosa recipient. Other P. aeruginosa R factors, including RP4, showed stable coexistence with the R931 group. It is proposed that RP4 and similar R factors be members of the P-1 compatibility group and that R931, R3108, R209, and R130 be members of a group termed P-2. The buoyant densities of all R factors examined were similar, about 1.716 to 1.719 g/cm(3). The content of R-factor deoxyribonucleic acid (DNA) relative to the total DNA varied among the different R factors, ranging from about 18 +/- 2% in log-phase cells of 931 (R931) to undetectable for 679 (R679). However, R679, which transferred from strain 679 at extremely low and irregular frequencies to an E. coli host, was shown to represent about 4% R-factor DNA in that host. The relative DNA content of R931 appeared to decline in the stationary growth phase of 931 (R931) or 280 (R931). R931 covalently closed circular DNA was isolated by ethidium bromide-CsCl gradient centrifugation and examined by electron microscopy. Two major molecular distributions existed, having contour lengths of 0.5 and 12.4 mum. The molecular weights were estimated to be 10(6) and 25 x 10(6). Both molecules were under relaxed replication control. R factor R931 exists as a naturally occurring high-frequency transfer system in P. aeruginosa strains 931 and 1310. However, in strain 280 it acts as if subject to fertility repression. Other members of the P-2 compatibility group also are high-frequency transfer systems in the natural host and in strain 1310. RP4 is restricted from recipient strain 1310. Some additional recipient effects were noted in that strains 1310 or 280 sometimes differed in recipient effectiveness with a given donor. Agglutination reactions with absorbed antiserum were able to distinguish between two members of the same R-factor compatibility group, R931 and R3108. PMID- 4208296 TI - Mechanisms of R factor R931 and chromosomal tetracycline resistance in Pseudomonas aeruginosa. AB - The mechanism of tetracycline resistance mediated by R931 (a Pseudomonas aeruginosa R factor not yet successfully transferred to Escherichia coli recipients) was examined. In strain 931 (R931) (minimal inhibitory concentration [MIC] 200 mug/ml) significant tetracycline uptake did not occur until 100 mug of tetracycline per ml was included in uptake studies. The introduction of R931 into strain 280 resulted in a significant decline in (3)H-tetracycline uptake. In both strains 931 (R931) and 280 (R931), a further reduction in tetracycline uptake resulted from pre-incubation with 1 mug of tetracycline per ml. Tetracycline resistance in R(-)P. aeruginosa strains 1731, 1885, and 494, considered to be of chromosomal origin, was associated with a lack of tetracycline uptake until the MIC of the strain was obtained. No evidence of tetracycline inactivation or ribosomal resistance was detected in R(-) or R(+) strains. The MIC for R(-) strains was generally about 25 mug/ml and that for R(+) strains was 75 to 200 mug/ml. PMID- 4208297 TI - Pharmacokinetic studies in animals and humans of a new cephalosporin, the sodium salt of 7-cyanacetamidocephalosporanic acid. AB - The sodium salt of 7-cyanacetamidocephalosporanic acid (CAA) had a relatively short serum half-life in rabbits (21 min by intravenous and 30 min by intramuscular administration) and in humans (33 min by intravenous injection). The drug was not extensively bound (about 35%) to serum in either species. Even after large doses (500 mg/kg), CAA was not well absorbed from the gastrointestinal tract of rabbits. Urinary excretion of antibacterial activity was rapid after intravenous and intramuscular administration in rabbits and after intravenous administration in men. Expressed as unchanged CAA, antibacterial activity appeared in the urine to the extent of 84% for humans, 35% for rabbits and 32% for rats. Excretion proceeded partly by active renal tubular secretion in rabbits. In this latter species, low concentrations of the active drug were detected in cerebrospinal fluid and bile after an intravenous dose of 25 mg/kg. CAA was well tolerated after intravenous administration of a single dose in both rabbits and humans. PMID- 4208298 TI - Immunological recognition of polynucleotide structure. PMID- 4208299 TI - Transfection in B. subtilis. PMID- 4208300 TI - Recent advances in molecular pathology. Regression of atherosclerosis--a perspective. PMID- 4208302 TI - Effects of elevated temperature on the mycetome and symbiotes of the bed bug Cimex lectularius (Heteroptera). PMID- 4208301 TI - Proceedings: Effect of growth hormone release inhibiting hormone on the release of growth hormone and other pituitary hormones in man. PMID- 4208303 TI - Effect of prolonged storage of spores on field applications of Nosema locustae (Microsporida: Nosematidae) against grasshoppers. PMID- 4208304 TI - Pathological effects of Urosporidium (Haplosporida) infection in microphallid metacercariae. PMID- 4208306 TI - Total-body potassium and lean body mass in males with an abnormal sex chromosome complement. PMID- 4208305 TI - The phylogeny of human globin genes investigated by the maximum parsimony method. PMID- 4208307 TI - The effect of sex hormones on rat liver carbonic anhydrase. PMID- 4208308 TI - Some dynamic properties of linear, hyperbolic and sigmoidal multi-enzyme systems with feedback control. PMID- 4208309 TI - [Effect of nitroglycerin on the duration of electrical and mechanical systole in patients with ischemic heart disease]. PMID- 4208311 TI - [Changes induced by poly-2-vinylpyridine-N-oxide in susceptibility of macrophages to tubercular infection]. PMID- 4208310 TI - Pentane production by peanut lipoxygenase. PMID- 4208312 TI - [Objective control of accuracy of centering in radiotherapy]. PMID- 4208313 TI - [Wolfram scattering foil--a source of mixed gamma-electron radiation]. PMID- 4208314 TI - Studies of complement levels in normal human pregnancy. PMID- 4208315 TI - The integrative approach in medicine--implications of neuroendocrine mechanisms. PMID- 4208316 TI - Sex differences in passion and play. PMID- 4208317 TI - Sexuality and reproduction. PMID- 4208318 TI - Observations on the development of antibodies to thiamine tetrahydrofurfuryl disulfide in rabbits. PMID- 4208319 TI - [Immunoglobulins of blood serum in diabetes mellitus]. PMID- 4208320 TI - Structural organization of developing chloroplasts in Euglena. PMID- 4208321 TI - The effect of ethylenediaminetetraacetic acid on yeast cell membranes. PMID- 4208322 TI - [Electron microscopical investigations on Paulinella chromatophora Lauterborn, a thecamoeba containing blue-green endosymbionts (Cyanelles) (author's transl)]. PMID- 4208323 TI - Pyrazapon (CI-683): a new antianxiety agent. PMID- 4208324 TI - [Microbial agents and therapy of endometritis in cows]. PMID- 4208325 TI - [Cytochemical study of alkaline phosphatase in leukocytes of farm animals. I]. PMID- 4208326 TI - [Studies on adenoviruses in birds in Bulgaria. I. Demonstration of antibodies against CELO viruses in the blood serum of birds by agar gel precipitation]. PMID- 4208327 TI - Childhood asthma in Finland. A survey of 559 patients. PMID- 4208328 TI - Histochemical localization of acetylcholinesterase enzyme in the 'limbic system' of the brain of the squirrel monkey (Saimiri sciureus). PMID- 4208329 TI - Organon thalamo-chorioidalis in the taenia thalami of the cat and other mammals. PMID- 4208330 TI - Serine neutral proteinase from Bacillus pumilus as metalloenzyme. PMID- 4208331 TI - Capacity of group A, B, C, D, and G streptococci to agglutinate sensitized sheep red cells. PMID- 4208332 TI - Association of capsid protein with Semliki Forest virus messenger RNAs. PMID- 4208333 TI - "Pitting" and "corrosion" of the surface of agar cultures by colonies of some bacteria from the respiratory tract. PMID- 4208334 TI - Search for thymidine phosphorylase, nucleoside deoxyribosyltransferase and thymidine kinase in genus Neisseria. PMID- 4208335 TI - Bacteriophage typing of Mycobacterium ranae (Fortuitum). The use of unadapted and adapted phages in the development of a typing system. PMID- 4208336 TI - Encephalogenic cardiomyopathy after stimulation of the brain stem in monkeys. PMID- 4208337 TI - Patient compliance with antibiotic regimens. PMID- 4208338 TI - Problems of treatment of anorexia nervosa. PMID- 4208339 TI - The treatment of advanced prostatic carcinoma with medroxyprogesterone. PMID- 4208340 TI - A comparison of propranolol and prindolol in the treatment of essential hypertension. PMID- 4208341 TI - Clinical evaluation of SE 1520 in the treatment of hypertension. PMID- 4208343 TI - A double-blind clinical evaluation of the safety and efficacy of phentermine hydrochloride (Fastin) in the treatment of exogenous obesity. PMID- 4208344 TI - Doxycycline treatment in gonorrhea. PMID- 4208342 TI - A double-blind comparison of two oral contraceptives containing 50 mu g. and 30 mu g. ethinyl estradiol. PMID- 4208345 TI - The rapidity of the effect of different types of topical corticosteroids: a double-blind comparison between Diproderm ointment 0.05 percent and Calmuril Hydrocortisone 1 percent. PMID- 4208347 TI - Clinical observations on the use of a long-acting phenothiazine (fluphenazine enanthate) in chronic schizophrenics. PMID- 4208346 TI - Osteomyelitis associated with vascular insufficiency. PMID- 4208348 TI - The use of mesoridazine in geriatrics. PMID- 4208349 TI - Structure-activity relationships within the class of 1,4-benzodiazepines: presence of chlorine and central nervous system activities. PMID- 4208350 TI - Bioavailability and activity of betamethasone 17-benzoate in gel and cream formulations: comparison with proprietary topical corticosteroid preparations in the vasoconstrictor assay. PMID- 4208351 TI - Characteristic actions of CDP-choline on the central nervous system. PMID- 4208352 TI - A comparison of three laboratory tests for pregnancy diagnosis in the mare. PMID- 4208353 TI - The neutral proteases of human granulocytes. Isolation and partial characterization of granulocyte elastases. PMID- 4208354 TI - Secondary isotope effect in the phosphorylase reaction. PMID- 4208355 TI - Purification and some properties of an endocellular sucrase from a constitutive mutant of Bacillus subtilis Marburg 168. PMID- 4208356 TI - Fluorescent products from aging Drosophila melanogaster: an indicator of free radical lipid peroxidation damage. PMID- 4208357 TI - Are there major degenerative changes in the flight muscle of ageing diptera? PMID- 4208358 TI - [Ambulatory long-term treatment of hypertension with Briserin mite]. PMID- 4208359 TI - Administrative problems and solutions in screening for gonorrhea. PMID- 4208360 TI - Orally administered betahistine and regional cerebral blood flow in cerebrovascular disease. PMID- 4208361 TI - Inhibition of clofibrate-induced antidiuresis by glybenclamide in patients with pituitary diabetes insipidus. PMID- 4208362 TI - Perfusion fixation of the kidney of the domestic fowl. PMID- 4208364 TI - [Effect of autothermostasis of microbial populations and its influence on the growth and gas metabolism of microorganisms]. PMID- 4208363 TI - Cellular distribution of beta-trace protein in CNS and brain tumours. AB - The low-molecular weight beta-trace protein constitutes about seven per cent of the total protein content in human cerebrospinal fluid. Within the central nervous system the protein is found predominantly in white matter and fractions enriched in glial cells. Immunofluorescence studies on sections of monkey brains show that beta-trace protein is particularly localized to cells such as astrocytes and oligodendrocytes. Significantly higher amounts of beta-trace protein are found in brain tumours derived from glial cells than in other tumours. PMID- 4208366 TI - [Electron miscroscopic study of the morphogenesis of the blue-green algae virus]. PMID- 4208365 TI - [Characteristics of the development of oligonitrophils in assimilating bound forms of nitrogen]. PMID- 4208367 TI - [Properties of a filamentous mutant of the blue-green alga Anacystis nidulans sensitive to radiation]. PMID- 4208368 TI - [Comparison of the growth dynamics of thermophilic and mesophilic bacteria]. PMID- 4208369 TI - Combined intrathecal and intramuscular gentamicin for gram-negative meningitis. Pharmacologic study of 21 patients. PMID- 4208370 TI - Acquired phagocyte dysfunction. A complication of the hypophosphatemia of parenteral hyperalimentation. PMID- 4208371 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1974. PMID- 4208372 TI - Editorial: Hypoalimentation during hyperalimentation. PMID- 4208374 TI - Letter: Contamination of fluid for parenteral nutrition. PMID- 4208373 TI - Editorial: Vasodilator therapy of myocardial infarction. PMID- 4208375 TI - Organochlorine residues in woodcock wings, 11 states--1970-71. PMID- 4208377 TI - Residues of PCB's and PCT's in Canadian and imported European cheeses, Canada- 1972. PMID- 4208376 TI - Residues of mirex and certain other chlorinated hydrocarbon insecticides in beef fat--1971. PMID- 4208378 TI - Methamphetamine effects on responding under a multiple schedule of shock presentation. PMID- 4208379 TI - Suppression of cocaine self-administration by extinction and punishment. PMID- 4208381 TI - Psychiatric inpatients in 1982: how many beds? PMID- 4208380 TI - Long-term treatment of endogenous depression with nortriptyline with control of plasma levels. PMID- 4208382 TI - Medical Research Council Unit on the Development and Integration of Behaviour. PMID- 4208383 TI - Inter-laboratory discrepancies in serum immunoglobulin estimations. PMID- 4208384 TI - The natural history of bacterial colonization of the newborn in a maternity hospital. I. PMID- 4208385 TI - Editorial: Oral therapy in diabetes mellitus. PMID- 4208386 TI - Bilateral symmetrical periarticular trauma in epileptics. PMID- 4208388 TI - Factor VIII, a series of homologous oligomers and a complex of two proteins. PMID- 4208387 TI - Failure of chemotherapy in treatment of giant condyloma acuminata (Buschke Loewenstein tumor). PMID- 4208389 TI - Shwartzman reaction in an HL-A-identical renal allograft. PMID- 4208390 TI - [Diamine oxidase activity in certain human fetal tissues]. PMID- 4208391 TI - [New (technical) protease preparation of Streptomyces griseus]. PMID- 4208392 TI - [Laboratory diagnosis of penicillin allergy]. PMID- 4208394 TI - [Is the "endangitis obliterans placentae" caused by an intrauterine infection? (author's transl)]. PMID- 4208393 TI - [Serum level of immunoglobulins under intensive cytostatic treatment]. PMID- 4208395 TI - [Simple purification of Australia antigen through acid dissociation of antigen antibody complexes]. PMID- 4208396 TI - Chronogenetics. Its foundations, scope, and impact. PMID- 4208397 TI - Experimental middle ear effusions: an immunofluorescent study. PMID- 4208398 TI - Tympanoplasty for bony ossicular fixation. PMID- 4208400 TI - Letter: Gold nephropathy and glucocorticoids. PMID- 4208399 TI - Staphylococcal endocarditis following septorhinoplasty. PMID- 4208401 TI - Immunological enhancement of atherogenesis in rabbits. Persistent susceptibility to atherogenic diet following experimentally induced serum sickness. PMID- 4208402 TI - Alveolar macrophage function in immunized, burned rats. PMID- 4208403 TI - A comparative study of the distribution of soluble and particulate glycyl-L leucine hydrolase in the small intestine. PMID- 4208404 TI - Increased glucuronidation of bilirubin in man and rat by administration of antipyrine (phenazone). PMID- 4208406 TI - The ventilatory response in diabetic ketoacidosis. PMID- 4208405 TI - Effect of nicotinic acid on cholesterol metabolism in monkeys. PMID- 4208407 TI - Hypothalamic control of anterior pituitary hormone secretion--characterized hypothalamic-hypophysiotropic peptides. PMID- 4208408 TI - Establishment of multiple lymphoblastoid lines from single lymph nodes and study of their immunoglobulin synthesis. PMID- 4208409 TI - The underdevelopment of health or the health of underdevelopment: an analysis of the distribution of human health resources in Latin America. PMID- 4208410 TI - Percent charging of transfer ribonucleic acid and levels of ppGpp and pppGpp in dormant and germinated spores of Bacillus megaterium. AB - The levels of transfer ribonucleic acids (tRNAs) specific for 14 amino acids were almost identical in dormant spores and in spores germinated from 6 to 75 min. Germinated spore tRNAs specific for all amino acids tested were between 63 and 93% charged, and there was no significant change in this value from 6 to 75 min of germination. In contrast, tRNAs isolated from dormant spores specific for nine different amino acids were almost completely(>93%) uncharged. However, some dormant spore tRNAs, i.e., those for arginine, histidine, isoleucine, and valine, showed significant (21 to 72%) levels of aminoacylation. Dormant spores contained no detectable guanosine penta- (pppGpp), tetra- (ppGpp), or triphosphate (GTP). However, these nucleotides appeared in the first minutes of germination, and thereafter all increased in parallel with a ratio of pppGpp plus ppGpp to GTP of 0.07 to 0.11, which is characteristic of unstarved vegetative cells. PMID- 4208411 TI - Physiological influences on cell division patterns in the div IV-B1 MINIcell producing mutant of Bacillus subtilis. AB - The proportion of abnormal divisions resulting in minicells is influenced by growth stage and medium composition. PMID- 4208412 TI - Acceleration of dextransucrase activity of Streptococcus mutans by secretory immunoglobulin A. AB - The effect of immunoglobulins on the activity of dextransucrase purified from Streptococcus mutans strain HS-6 is described. When human salivary immunoglobulin A (IgA) or colostral IgA, either natured or denatured, was incubated with dextransucrase, the rate of the dextran synthesis was markedly accelerated, whereas human serum IgA or IgG neither accelerated nor inhibited the enzyme activity. The results suggest that a portion unique for secretory IgA, the secretory component, might be related to the enzyme acceleration. On the other hand, specific rabbit antiserum against the dextransucrase inhibited completely dextran synthesis by the enzyme. PMID- 4208413 TI - Specificity and induction of undecyl acetate esterase from Pseudomonas cepacia grown on 2-tridecanone. AB - Undecyl acetate esterase from Pseudomonas cepacia grown on 2-tridecanone was strongly inhibited by organophosphates and other esterase inhibitors. Also, p chloromercuribenzoate at 1 x 10(-4) M showed a 70% inhibition of esterase activity. The enzyme hydrolyzed both aliphatic and aromatic acetate esters at substrate concentrations of 0.25 M. Under these conditions the highest reaction rate was toward undecyl acetate. No lipase or proteolytic activity was demonstrated. Undecyl acetate esterase was classified as a carboxylesterase (B esterase). Cell-free activity studies on the production of undecyl acetate esterase grown on different carbon sources plus zymogram studies demonstrated that the enzyme was inducible when 2-tridecanone, 2-tridecanol, undecyl acetate and, to a lesser extent, 1-undecanol were growth substrates. Induction of undecyl acetate esterase during oxidation of 2-tridecanone supports the view that undecyl acetate is an intermediate in the degradation of the methyl ketone. PMID- 4208414 TI - Tests for deoxyribonucleic acid synthesis in toluenized Bacillus subtilis cells. AB - Several tests were devised to further characterize deoxyribonucleic acid (DNA) synthesis in toluenized Bacillus subtilis cells. Vigorous agitation of toluenized cells (localization test) demonstrated that the DNA replication is exclusively a cell-associated process. A DNA "repair" condition was also applied to toluenized cells and shown to be distinct from DNA replication in its DNA polymerase I dependency and its ability to synthesize DNA on template which is either cell associated or free, outside the cell. This repair condition was used in conjunction with the localization test to demonstrate the penetration of deoxyribonuclease I and possibly DNA polymerase I into toluenized cells. Therefore, we suggest that the localization test can be used to test the penetration of proteins into toluenized cells for both the DNA repair and replication processes. PMID- 4208415 TI - Pyruvate carboxylase deficiency in pleiotropic carbohydrate-negative mutant strains of Pseudomonas aeruginosa. AB - Cell extracts of Pseudomonas aeruginosa strain PAO were found to contain pyruvate carboxylase activity. Specific activities were minimal when cells were grown on Casamino Acids, acetate, or succinate, but were three- to fourfold higher when cells were grown in glucose, gluconate, glycerol, lactate, or pyruvate minimal media. The reaction in crude cell extracts and in partially purified preparations was dependent on pyruvate, adenosine 5'-triphosphate, and Mg(2+), but was not affected by either the presence or absence of acetyl coenzyme A. Activity was nearly totally inhibited by avidin and this inhibition was substantially blocked by free biotin in incubation mixtures. Cell extracts were shown to fix (14)CO(2) in a reaction that had these same characteristics. Eight pleiotropic, carbohydrate-negative mutant strains of the organism were isolated after nitrosoguanidine mutagenesis. Each mutant strain grew normally in acetate, succinate, and citrate minimal media but failed to utilize glucose, gluconate, 2 ketogluconate, mannitol, glycerol, lactate, and pyruvate as sole sources of carbon and energy. These strains were found by quantitative transductional analysis with phage F116 to form a single linkage group. Cell extracts of each mutant strain were either lacking or severely deficient in pyruvate carboxylase activity. Spontaneous revertants of five of the eight strains were isolated and found to recover simultaneously both pyruvate carboxylase activity and the ability to utilize each of the C(6) and C(3) compounds. A second linkage group of similar mutant strains that grew on the C(3) compounds was found to contain normal levels of pyruvate carboxylase activity, but each strain was deficient in an enzyme of the Entner-Doudoroff pathway. PMID- 4208417 TI - The mediator of cellular immunity. VII. Localization of sensitized lymphocytes in inflammatory exudates. AB - Peritoneal exudates induced in rats infected with Listeria monocytogenes contain sensitized lymphocytes which can protect normal recipients against a Listeria challenge. The protective cells arise in lymphoid tissue remote from the peritoneal cavity. Those formed in the caudal lymph nodes of subcutaneously infected rats are delivered to the thoracic duct and hence to the blood from where they are drawn into exudates. Immunoblasts are the most immature members of this protective cell population and they alone among the cells in central lymph localize in exudates induced by killed bacteria. They do so in substantial numbers, but only during the early postinduction period. The "homing" of immunoblasts to inflammatory foci seems to be determined by a general property of the cells rather than their immunological commitment; however, the intense inflammation induced by organisms to which an animal has been specifically sensitized is accompanied by an exuberant influx of immunoblasts into lesions. Sensitized lymphocytes that extravasate in the inflamed peritoneal may generate more of their own kind, but some give rise to small lymphocytes. The latter also have protective properties and, with time, comprise an increasing portion of the protective cell population. The results imply that the tissue disposition of sensitized lymphocytes in the body is determined by a complementary relationship between blood-borne immunoblasts and vascular endothelium in inflamed tissue. The results also provide a plausible explanation for the concentration of sensitized lymphocytes at sites of microbial implantation where they alone would be expected to collaborate with monocyte-derived macrophages in the control of infection. PMID- 4208416 TI - Induction of partial immunologic tolerance in rats and progressive loss of cellular antigenicity in Gross virus lymphoma. AB - Gross virus-induced lymphoma cells express strong virus-associated (Gross murine leukemia virus [G-MuLV]) antigens and are consistently rejected when grafted in normal adult syngeneic rats. By contrast, similar grafts are tolerated and allowed to grow progressively by rats that have been injected at birth with deaggregated G-MuLV antigens. However, the tolerance induced by this procedure is only partial as the grafted lymphoma cells lose their G-MuLV membrane antigens. These cells showing an antigenic disjunction, with negative membrane and positive cytoplasmic G-MuLV antigenic expression, become transplantable in normal nonconditioned adult recipients. By further grafting, the expression of cytoplasmic G-MuLV antigens is similarly lost while the lymphoma cells substantially increase their transplantability, rate of growth, and capacity for metastasis. PMID- 4208419 TI - The nicotinic cholinergic receptor protein: improved purification method, preliminary amino acid composition and observed auto-immuno response. PMID- 4208418 TI - Nuclear localization of S-100 protein. PMID- 4208420 TI - Immunological approach to the characterization of cholinergic vesicular protein. PMID- 4208421 TI - Immunochemical studies on cholinergic synaptic vesicles. PMID- 4208422 TI - Electrophoretic profiles of aqueous-soluble proteins of human cerebral cortex: population and developmental characteristics. PMID- 4208423 TI - Increased concentrations of acidic metabolites of dopamine in the superior cervical ganglion following preganglionic stimulation in vivo. PMID- 4208424 TI - Brain sphingolipids in I cell disease (mucolipidosis II). PMID- 4208425 TI - Antibacterial efficiency of mercurials. PMID- 4208426 TI - Intestinal motor effects of a unique analgesic agent. PMID- 4208427 TI - Letter: Relationship between pH and antibacterial activity of glutaraldehyde. PMID- 4208428 TI - Intracellular J chain in mouse plasmacytomas secreting IgA, IgM and IgG. PMID- 4208429 TI - Lipopolysaccharides inhibit lymphosarcoma cells of bone marrow orgin. PMID- 4208430 TI - Complement-mediated mixed aggregation of murine spleen cells. PMID- 4208432 TI - Infectious particles in a marine ciliate. PMID- 4208431 TI - Bacteroids in the ovaries of a tsetse fly. PMID- 4208433 TI - Deposition of DDE and polychlorinated biphenyls in dated sediments of the Santa Barbara basin. AB - Analysis of dated oceanic sediments from the Santa Barbara Basin of the Southern California Bight has shown that deposition of polychlorinated biphenyls (PCB) began about 1945 and that DDE [1,1-dichloro-2-2-bis(p-chloro-phenyl)ethylene] first appeared in sediments deposited about 1952. Concentrations of both show a progressive increase through 1967; estimated deposition rates (in grams per square meter per year) in 1967 of DDE and PCB were 1.9 x 10(-4) and 1.2 x 10(-4), respectively. PMID- 4208434 TI - [Properties of motile enterococci]. PMID- 4208435 TI - [Continuous cultivation as a method of studying the physiology of microorganisms (review)]. PMID- 4208436 TI - [Effect of the Hly-factor on the interaction of E. coli K12 and Sh. flexneri avirulent hybrid with transplantable cell cultures]. PMID- 4208437 TI - [Oral vaccines for preventing intestinal infections (literature review)]. PMID- 4208438 TI - [Shigella antigens synthesized under control of the resistance plasmid]. PMID- 4208439 TI - [Preparation and properties of an enterotoxin from nonagglutinating vibrios]. PMID- 4208440 TI - Addison's disease--serological studies. PMID- 4208441 TI - The effect of thyrotrophin releasing hormone on the release of thyrotrophin and other pituitary hormones in man under basal conditions and following adrenergic blocking agents. PMID- 4208442 TI - Iodoproteins in congenital goitre with elevated levels of serum TSH and T3. PMID- 4208443 TI - Thyrotrophin releasing factor (TRF) in cerebrospinal fluid of the 3rd ventricle of rat. PMID- 4208444 TI - Para-articular ossifications after total hip replacement. PMID- 4208445 TI - On the transferrin concentration in serum of sows and growing pigs and in sow colostrum. PMID- 4208446 TI - Inborn errors of lipid metabolism. PMID- 4208447 TI - Liver injury in protein-calorie malnutrition: an electron microscopic study. PMID- 4208448 TI - Stature and lean body mass. PMID- 4208449 TI - Impaired cellular immunity in marasmic infants. PMID- 4208450 TI - Serum levels of immunoglobulins, cell-mediated immunity, and phagocytosis in protein-calorie malnutrition. PMID- 4208451 TI - Some effects of malnutrition on the immune response in man. PMID- 4208452 TI - Effects of protein insufficiency on immune responsiveness. PMID- 4208453 TI - An evaluation of factors associated with the depression of immunity in malnutrition and in measles. PMID- 4208454 TI - Something old, something new in the visual act of the patient with strabismus. PMID- 4208455 TI - Bacterial microflora of the upper gastrointestinal tract in infants without diarrhoea. PMID- 4208457 TI - [Primary structure of human erythrocyte carbonic anhydrase B. 2. Cleavage with cyanogen bromide and the sequence of residues 1-148]. PMID- 4208456 TI - Iodine balance studies in protein-calorie malnutrition. PMID- 4208458 TI - On the increased precursor incorporation into the DNA of rat liver mitochondria irradiated in vitro. PMID- 4208459 TI - The use of immunoadsorbent columns for the isolation of antibodies specific for antigens associated with human bronchogenic carcinoma. AB - An immunoadsorbent technique is described whereby tumour-specific antibodies may be isolated. Extracts from normal human lung tissue were pooled and bound to cyanogen bromide activated Sepharose 4B. Antisera raised in rabbits to a variety of extracts from human bronchogenic carcinoma were passed through these immunoadsorbent columns to yield antisera specific for tumour-associated antigens as demonstrated by immunodiffusion and immunoelectrophoresis. PMID- 4208461 TI - Reinterpretation of hyperamylasemia in diabetic coma. PMID- 4208462 TI - Immunochemical measurement of lipoprotein-X. PMID- 4208463 TI - Metabolic effects of sodium bicarbonate in management of diabetic ketoacidosis. PMID- 4208464 TI - Effects of hypoglycemic sulfonamides on glucagon and insulin secretion in ducks and dogs. PMID- 4208465 TI - Metabolism of trehalose in Euglena gracilis. Beta glucose 1,6-bisphosphate, activation factor of phosphoglucomutase for beta glucose 1-phosphate. PMID- 4208466 TI - [Fetomaternal immunization of women during pregnancy with HL-A alloantigens and ABO and Rh antigens]. PMID- 4208467 TI - If all the sea were PCB. PMID- 4208468 TI - Effects of anti-human neutrophil antibodies in vitro. Quantitative studies. AB - Opsonic, antiphagocytic, cytotoxic, and metabolic effects of homologous and heterologous antibodies against human neutrophils were analyzed by means of quantitative assays to facilitate detection of antibody activity, and to probe membrane function of these cells. Normal human neutrophils were purified by gradient centrifugation, sensitized with heat-inactivated antineutrophil antisera, and incubated with rabbit alveolar macrophages in balanced salt solution containing nitroblue tetrazolium. The macrophages engulfed sensitized neutrophils and reduced nitroblue tetrazolium to formazan in phagocytic vacuoles. The initial rate of nitroblue tetrazolium reduction by macrophages ingesting the neutrophils was measured spectrophotometrically. Neutrophils treated with rabbit anti-human leukocyte antiserum or IgG, with sera from mothers of infants with neonatal isoimmune neutropenia, and with 27% of sera from frequently transfused patients promoted rapid rates of nitroblue tetrazolium reduction by alveolar macrophages. This indicates that antineutrophil antibodies without added complement opsonized neutrophils for ingestion by the macrophages. Some sera from frequently transfused patients with opsonic activity for certain donors' neutrophils did not agglutinate these neutrophils (44%), did not lyse them in the presence of fresh plasma (47%), and did not inhibit phagocytosis of particles by the neutrophils (26%). The reverse was not observed. The opsonic activity of antineutrophil antiserum appears to be the most sensitive and a quantitative means of detecting antibody activity in vitro.Low concentrations of rabbit anti human leukocyte antisera or IgG stimulated the ingestion rate of unopsonized or opsonized particles by human neutrophils, and, as previously reported by others, enhanced rates of oxidation of [1-(14)C]glucose by the cells. High concentrations of the antisera or IgG inhibited ingestion. All concentrations of homologous antineutrophil antisera tested only inhibited ingestion of particles by neutrophils and none altered rates of resting glucose oxidation by the cells. The findings suggest that heterologous antibodies disturb membrane antigens that trigger oxidative metabolism and enhance as well as inhibit ingestion, and that these antigens are common to all human neutrophils. In contrast to other studies with antimacrophage antibodies, antineutrophil antibodies altered phagocytic rates of both unopsonized and opsonized particles although there were differences in dose-response curves depending on the type of particle tested. Thus, antineutrophil antibodies do not merely cover selected receptor sites. PMID- 4208469 TI - The effects of the natriuretic factor from uremic urine on sodium transport, water and electrolyte content, and pyruvate oxidation by the isolated toad bladder. AB - The urine of patients with chronic uremia contains a gel filtration fraction that is natriuretic in the rat. The effects of this fraction on the isolated urinary bladder of the toad were examined in the present studies. When added to the serosal surface of the bladder, a significant and substantial fall in short circuit current and potential difference was observed. The changes began after a lag period of at least 10 min and continued over a period of 60 min. The decrease in short-circuit current at the end of 1 h averaged 44%. The same fraction from the urine of normal subjects produced no significant change in either short circuit current or potential difference. When the isolated epithelial cells from the toad bladder were incubated in the presence of the inhibitor, intracellular sodium content increased significantly. There was no change in intracellular water content; hence the intracellular concentration of sodium increased by a mean of 7 meq/liter. The changes in intracellular potassium content and concentration were not satistically significant. When the isolated epithelia were incubated with the uremic factor, there was also a significant decrease in pyruvate utilization in relation to cells from paired hemibladders incubated in the absence of the fraction. The fraction from normal subjects produced no change in either intracellular sodium content or pyruvate oxidation. The results suggest that the inhibitor acts from the serosal surface, inhibits sodium transport across the serosal barrier, and produces a decrease in substrate utilization in association with the change in transepithelial sodium transport. PMID- 4208471 TI - The mechanism of uridine diphosphate-sugar-4-epimerase reactions. Isotope discrimination with 4-tritiated substrates. PMID- 4208472 TI - Deoxyribonucleic acid polymerase from Tetrahymena pyriformis. Purification and properties of the major activity in exponentially growing cells. PMID- 4208470 TI - Hypothalamic-pituitary function in diverse hyperprolactinemic states. AB - Prolactin secretion in normal adults is characterized by periods of episodic secretion which increase in magnitude during sleep. In this study, we report the 24-h mean prolactin concentrations, prolactin secretory patterns, and associated pituitary hormone function in nine patients (seven women and two men) with hyperprolactinemia of diverse etiologies. Four of the women and one of the men had clinically demonstrable pituitary tumors, one boy had a hypothalamic tumor, and the three other women had "functional" hyperprolactinemia. The 24-h mean prolactin concentrations derived from averaging the 20-min interval samples for 24 h ranged from 28.6 to 1,220 ng/ml. The plasma prolactin patterns in these patients showed persistence of episodic secretion in all and loss of the normal sleep-wake difference in plasma prolactin in seven of nine. Three of the patients with galactorrhea and comparable 24-h mean prolactin concentrations (58.3, 59.7, and 64.3 ng/ml) showed similar prolactin secretory patterns despite different etiologic mechanisms. Evaluation of the secretory patterns of luteinizing hormone (LH) in these patients showed loss of normal pulsatile LH release and a low 24-h mean LH concentration in the patient with the pituitary tumor, while the two patients without clinically demonstrable pituitary tumors ("post-pill" galactorrhea and "idiopathic" galactorrhea) showed normal LH secretory patterns and 24-h mean LH concentrations. The 24-h mean cortisol concentrations and secretory patterns were normal in five of the seven patients who had these parameters measured. The patient with the hypothalamic tumor had a low 24-h mean cortisol concentration and production rate and absent response to metyrapone. The patient with "idiopathic" galactorrhea had an elevated 24-h mean cortisol concentration but normal cortisol production rate and urinary 17-hydroxycorticoid excretion. Growth hormone secretion was abnormal in four of the patients (one with the hypothalamic tumor and three with pituitary tumors). Thyrotropin releasing hormone (TRH) administration in four patients resulted in normal TSH release in two patients (one of whom developed galactorrhea after the test), an absent response in the patient with the hypothalamic tumor, and a blunted response in one of the women with a pituitary tumor. The two men had low 24-h mean plasma testosterone concentrations (69 and 30 ng/100 ml) and symptoms of impotence and loss of libido. Five of the women (four with pituitary tumors and one with Chiari-Frommel syndrome) had either low 24-h mean LH concentrations, abnormal LH secretory patterns, or both. These data indicate that patients with hyperprolactinemia encompassing a varied etiological range frequently show loss of the normal sleep-associated increase in prolactin secretion as well as abnormalities in the regulation of the other hypothalamic pituitary-regulated hormones. The finding that the abnormalities in LH, growth hormone, thyrotropin, and cortisol (adrenocorticotrophic) secretion were almost uniformly confined to the patients with the clinically demonstrable hypothalamic or pituitary tumors suggests that the size of the lesion is the critical factor. PMID- 4208473 TI - On the specificity of phospho-N-acetylmuramyl-pentapeptide translocase. The peptide subunit of uridine diphosphate-N-actylmuramyl-pentapeptide. PMID- 4208474 TI - A proteolytically activated tyrosinase from frog epidermis. PMID- 4208475 TI - Cytoplasmic type 80 S ribosomes associated with yeast mitochondria. 3. Changes in the amount of bound ribosomes in response to changes in metabolic state. PMID- 4208476 TI - Subunit I of G beta replicase and 30 S ribosomal protein S1 of Escherichia coli. Evidence for the identity of the two proteins. PMID- 4208477 TI - How to handle secondary impression trays. PMID- 4208478 TI - Analysis of lung culture of Rickettsia prowazedi E strain with regard to its capacity of increasing virulence in passages on the lungs of white mice. PMID- 4208479 TI - The longterm care of the patient suffering from cerebral palsy. II. PMID- 4208480 TI - Synthesis and antifolate activity of 10-deazaminopterin. PMID- 4208481 TI - Synthesis of 1-deaza-N10-methylfolic acid and related compounds. PMID- 4208482 TI - Ethambutol. Synthesis of an unsaturated analog. PMID- 4208483 TI - The induction of tumour immunity in mice using glutaraldehyde-treated tumor cells. PMID- 4208484 TI - Immunological detection of antigen(s) associated with rat colon carcinoma. PMID- 4208485 TI - Riboflavin and adrenal cortex. PMID- 4208486 TI - The yellow baby. PMID- 4208487 TI - Present status of radium. PMID- 4208488 TI - [Listeriosis. I. Listeriosis in the light of bacteriologic and serologic studies]. PMID- 4208489 TI - Pulp structure in bilateral and opposing pairs of teeth. PMID- 4208490 TI - Biologic tests of a methyl methacrylate composite material. PMID- 4208491 TI - Selective destruction of the pigmented epithelium in the ciliary body of the eye. AB - Perfusion of the internal carotid artery with hypertonic solution selectively destroys most of the pigmented epithelium of the ciliary body of the monkey eye, converts fenestrated endothelium of capillaries to continuous endothelium, and transiently breaks down the blood-aqueous barrier. The nonpigmented epithelium regenerates and the intraocular pressure returns to normal even though the pigmented epithelium is permanently destroyed. PMID- 4208492 TI - [Infectious diseases and prescribing of antibiotic and chemotherapeutic drugs in general practice]. PMID- 4208493 TI - [Editorial: Antibiotics and chemotherapy in general practice]. PMID- 4208494 TI - [Marfan's syndrome and neurofibromatosis in the same patient]. PMID- 4208495 TI - [Environmental pollution with poisons]. PMID- 4208496 TI - [Comparative results of seeding Corynebacterium diphtheriae from different nutrient media]. PMID- 4208497 TI - [Comparative characteristics of antigen fractions of Corynebacterium diphtheriae]. PMID- 4208498 TI - [Isolation and characteristics of polysaccharide antigens from meningococci of groups A and C]. PMID- 4208499 TI - [Characteristics of new industrial strains of Mycobacterium tuberculosis]. PMID- 4208500 TI - [Biological properties of mycobacteriophages]. PMID- 4208501 TI - [Study of polysaccharides of streptococcus group A by immunodiffusion methods]. PMID- 4208502 TI - Effect of TRH, and short-term exposure to experimental stress or cold on the serum immunoassayable TSH concentration in the rat. PMID- 4208503 TI - In vitro procedure for measuring phagocytosis of blood neutrophils. PMID- 4208504 TI - Brucella ovis as a cause of abortion in ewes. PMID- 4208505 TI - Diagnosis of Mycobacterium bovis and Mycobacterium paratuberculosis infections in cattle by in vitro lymphocyte immunostimulation. PMID- 4208506 TI - Comparative in vitro activity of three aminoglycosidic antibiotics: BB-K8, kanamycin, and gentamicin. AB - Kanamycin, BB-K8, and gentamicin were tested in parallel against 1,037 bacterial strains isolated from clinical material. The activity of BB-K8 at 20 mug/ml was comparable to that of gentamicin at 8 mug/ml against Pseudomonas aeruginosa and against Enterobacteriaceae, with the exception of gentamicin-resistant strains of Proteus rettgeri and Providencia stuartii, in which case the activities of BB-K8 and kanamycin were the same. BB-K8 exhibited little or no activity against streptococci. The activity of BB-K8 was affected by pH and inoculum size. A regression graph for inhibition data with a 10-mug disk of BB-K8 was developed, and synergistic activity of penicillin and BB-K8 against Streptococcus faecalis was tested. PMID- 4208507 TI - Antiprotozoal activity of rubratoxin B. AB - Growth of Tetrahymena pyriformis HSM was inhibited by a concentration of 25 mug of rubratoxin B per ml of growth medium. The inhibitory effect of aflatoxin B(1) rubratoxin B mixtures on growth of T. pyriformis was induced by rubratoxin B only. Total cellular deoxyribonucleic acid increased in the presence of 5 mug of rubratoxin B per ml of growth medium, whereas higher concentrations (25 mug/ml of growth medium) were required before a decrease in total protein was observed. PMID- 4208508 TI - Enumeration of tubercle bacilli in sputum of patients with pulmonary tuberculosis. AB - A method for precise microscopic enumeration of acid-fast bacilli in the sputum of patients with pulmonary tuberculosis is described. The total number of acid fast bacilli and the number of culturable cell units of tubercle bacilli per milliliter of sputum were determined in 269 specimens from 28 patients collected prior to and/or during chemotherapy, to establish the usefulness of the procedure for evaluation of the effects of chemotherapy. Prior to or very early in the course of therapy, there was good agreement between microscopically and culturally measurable bacilli in 27 of 28 patients. Thereafter, there were systematic divergences in five patients and occasional divergences in most others. Yet, in general, in 20 of the 28 patients, the microscopically determined population provided a useful measure of the number of culturable tubercle bacilli present. Although the microscopic procedure does not allow species identification of mycobacteria or differentiation between viable and nonviable cells, it often provided, within hours rather than days or weeks, useful information on the residual burden of acid-fast bacilli in sputum during chemotherapy. The nature of the disease in those patients in whom microscopy failed to provide useful information is discussed. PMID- 4208509 TI - Inactivation of dried bacteria and bacterial spores by means of gamma irradiation at high temperatures. AB - Dried preparations with Streptococcus faecium, strain A(2)1, and spores of Bacillus sphaericus, strain C(I)A, normally used for control of the microbiological efficiency of radiation sterilization plants and preparations with spores of Bacillus subtilis, normally used for control of sterilization by dry heat, formalin, and ethylene oxide, as well as similar preparations with Micrococcus radiodurans, strain R(1), and spores of Bacillus globigii (B. subtilis, var. niger) were gamma irradiated with dose rates from 16 to 70 krad/h at temperatures from 60 to 100 C. At 80 C the radiation response of the spore preparations was the same as at room temperature, whereas the radiation resistance of the preparations with the two vegetative strains was reduced. At 100 C the radiation response of preparations with spores of B. subtilis was unaffected by the high temperature, whereas at 16 and and 25 krad/h the radiation resistance of the radiation-resistant sporeformer B. sphaericus, strain C(I)A, was reduced to the level of radiation resistance of preparations with spores of B. subtilis. It is concluded that combinations of heat and gamma irradiation at the temperatures and dose rates tested may have very few practical applications in sterilization of medical equipment. PMID- 4208510 TI - Effect of heat on the antimicrobial activity of brillant green dye. AB - Antimicrobial activity of brilliant green dye in Trypticase soy broth (BBL) is reduced and ultimately destroyed by prolonged autoclaving at 121 C. Loss of antimicrobial activity is accompanied by decolorization of the dye. This is consistent with other evidence that antimicrobial activity of brilliant green resides in the colored dye ion. The dye is not decolorized when heated in distilled water or peptone, but is decolorized by heating in glucose, glycine, or sodium dodecyl sulfate, showing that decolorization results from reaction with components of the medium. To ensure optimal results, it is recommended that bacteriological media be sterilized by heat prior to addition of brilliant green dye. PMID- 4208511 TI - Salmonellae in the environment around a chicken processing plant. AB - Studies have been conducted over a 2-year period to determine the extent to which a poultry processing plant served as a reservoir of salmonellae reaching the external environment, to examine the question of the importance of salmonellae in the environment, and to consider how best to control the spread of the organisms. The studies have been undertaken at a chicken processing plant handling between 75,000 and 80,000 birds per day. Populations of salmonellae and indicator bacteria were estimated in the raw wastes, through the waste treatment plant, and in the receiving stream waters. The results demonstrate that salmonellae are present in poultry processing wastes in a surprisingly constant relation to fecal coliforms (in excess of 1 Salmonella per 500 fecal coliforms), that serotypes in the environment are constantly changing, and that they may reflect unusual conditions in the processing plant, or a possible source of infection among human and animal residents of the environment. Disinfection of poultry processing wastes is recommended. PMID- 4208512 TI - Immobilized aspartase-containing microbial cells: preparation and enzymatic properties. AB - The immobilization of asparatase-containing Escherichia coli was investigated by various methods, and the most active immobilized cells were obtained by entrapment in a polyacrylamide gel lattice. Other asparatase-containing bacteria were also entrapped by the same method, and the enzymatically active immobilized cells were obtained. The aspartase activity of the immobilized E. coli cells was increased nine- to tenfold by autolysis of the cells entrapped in the gel lattice. Enzymatic properties of the immobilized E. coli cells were investigated and compared with those of the intact cells. The optimal pH was 8.5 for the immobilized cells and 10.5 for the intact cells. The aspartase activities of immobilized and intact cells were not activated by Mn(2+), which can activate the immobilized and native aspartases. The heat stability of the immobilized cells was somewhat higher than that of the intact cells. Bivalent metal ions such as Mn(2+), Mg(2+), Ca(2+) protected against thermal inactivation of the aspartase activity of the immobilized and intact cells. PMID- 4208513 TI - Proteinase activity in slow lactic acid-producing variants of Streptococcus lactis. AB - Variants of Streptococcus lactis that produce lactic acid slowly in milk were isolated by inducing plasmid loss in the wild type at 39 to 40 C. Such strains had lost most of their surface-bound proteinase activity and were designated prt( ). The specific proteinase activities of S. lactis C10 prt(+) whole cells and solubilized cell walls were 7 and 18 times, respectively, those of the prt(-) strain, but spheroplast lysates of prt(+) and prt(-) strains contained similar proteinase activity. S. lactis H1 showed a similar relative distribution of activity between prt(+) and prt(-) cellular fractions, although the overall level was lower. The limited growth in milk, characteristic of prt(-) strains, can be explained in terms of their low surface-bound proteinase activity. PMID- 4208514 TI - Membrane filter method for the isolation and enumeration of Pseudomonas aeruginosa from swimming pools. AB - A membrane filter technique using black membrane filters, MacConkey agar and fluorescence under ultraviolet (UV) light was investigated for the quantitative isolation of Pseudomonas aeruginosa from swimming pools. Three thousand four hundred forty-five samples were collected from public swimming pools and enumerated by this method over a 6-month period. Fluorescent cultures were isolated from 222 specimens. Seventy-seven of these fluorescent cultures were selected for biochemical screening, with 75 (97%) being verified as P. aeruginosa. To further assess the specificity and sensitivity of this UV screening technique, a comparative study was made of some morphological and biochemical characteristics of fluorescent pseudomonads obtained from different sources. The sensitivity of the method was unimpaired by either colony types or biochemical variations of P. aeruginosa. The failure of the other two fluorescent species, P. fluorescens and P. putida, to grow and/or fluoresce on MacConkey agar at 37 C illustrates the specificity of this technique. Further studies are needed to compare the viability of P. aeruginosa on MacConkey agar to that of efficacious nonselective media. PMID- 4208515 TI - [Therapy of vulvar carcinoma and its results (author's transl)]. PMID- 4208516 TI - Evaluation of fetal risk resulting from cord-entanglements during parturition. PMID- 4208517 TI - Sialic acid content of cortical bone. PMID- 4208518 TI - AMP-aminohydrolase of human skeletal muscle: partial purification and properties. PMID- 4208519 TI - Preparation of immobilized lactase. Continued studies on the enzymatic hydrolysis of lactose. PMID- 4208520 TI - [Comparative toxicity (mammals, insects, acarids) of new tri-substituted derivatives of thiophosphoric acid]. PMID- 4208521 TI - [Immunostimulating effect of phospholipid extracts from Ehrlich ascites cells and mouse spleen cells]. PMID- 4208522 TI - [Ultrastructural study of hepatocytes of newborn rats in established monolayer cultures]. PMID- 4208523 TI - Prevention of hemolysis induced by ellipticine (NSC-71795) in rhesus monkeys. PMID- 4208525 TI - [Juvenile diabetes mellitus]. PMID- 4208524 TI - Distribution and biochemical effects of pentylenetetrazol in brains of swine treated with a polychlorinated biphenyl. PMID- 4208526 TI - Partial characterization of aerolysin, a lytic exotoxin from Aeromonas hydrophila. AB - Conditions are defined for the production, in high titers, of an extracellular hemolytic toxin of Aeromonas hydrophila, here termed "aerolysin." Substantial purification of the toxin was accomplished by means of salt fractionation, dialysis, and gel filtration, with a yield of 24% of the starting activity. Analysis of the product by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate revealed a single, heavy protein band and a number of faint protein bands. The estimated molecular weight of the heavy band (50,000) was in close agreement with that (53,000) of the substance responsible for hemolytic activity as determined by gel filtration. Purified aerolysin is a labile substance, apparently protein. It is not inactivated by any of several proteases under the conditions employed nor is it inhibited by any of several lipids tested. About 0.1 mug administered to mice intravenously is lethal. The physical properties of aerolysin show considerable resemblance to those described for the exotoxin of Pseudomonas aeruginosa. PMID- 4208528 TI - Isolation of substances responsible for lymphokine activity from sensitized mouse spleen cells. AB - Cultures of brucella-sensitized mouse spleen cells exposed to Brucella abortus antigens in vitro release macrophage migration inhibition factor (MIF) and macrophage spreading factor. Subjecting the supernatants from such cultures to preparative scale electrophoresis in acrylamide gel yields several fractions, one of which contains both MIF and macrophage spreading factor. This material has properties attributable to guinea pig MIF: it is nondialyzable, heat stable, nontoxic to macrophages from heterologous murine donors, and has a greater anodal electrophoretic mobility than guinea pig serum albumin. Another fraction from the gel column inhibits macrophage spreading; its electrophoretic mobility is similar to that of guinea pig gamma globulin. Neither brucella antigen nor skin reactive substances were detectable in any acrylamide gel column fraction when tested by the mouse footpad induration assay technique. PMID- 4208527 TI - Characterization and evaluation of a soluble antigen complex prepared from the yeast phase of Histoplasma capsulatum. AB - Soluble yeast-phase (YPS) antigen preparations (Reeves et al., 1972) were obtained from three strains of Histoplasma capsulatum. These were analyzed by agar-gel diffusion and complement fixation tests with human sera from known cases of histoplasmosis. Two of the preparations contained the H and M antigens normally found in histoplasmin, whereas the third preparation contained the H but not the M antigen. In addition, a group of unknown antigens, designated as the Y (yeast) antigens, were demonstrated in all three YPS preparations. On the basis of Sephadex gel filtration data, the molecular weight of the YPS M antigen was estimated to range from 117,000 to greater than 200,000; that of the YPS H antigen was estimated to range from about 60,000 to greater than 200,000; and that of the Y antigens was estimated to range from less than 10,000 to 100,000. Complement fixation tests with human homologous and heterologous sera showed that the Y antigens were specific for H. capsulatum; Y antigens were not detected in the single lot of histoplasmin used in this study. When 60 human histoplasmosis sera and serum samples from nine animals experimentally infected with H. capsulatum were analyzed, it was found that antibodies to the Y antigens occurred with about the same frequency as antibodies to the H antigen but with less frequency than that of antibodies to the M antigen. When used in rabbits as immunogens for the preparation of specific antisera to H. capsulatum, the components of the YPS preparations caused the formation of numerous cross reacting antibodies. The data from this study show that the value of the YPS preparations for the serological diagnosis of histoplasmosis rests on the specificity of the H, M, and Y antigens and on the fact that the primary production of antibodies is restricted to these antigens in the course of natural infections. The YPS preparations were found to be stable for a period of at least 11 months under a variety of storage conditions and temperatures. Data obtained with various killing agents and metabolic inhibitors suggest an improved method for preparing the YPS antigens by using a suitable strain and killing the cells with iodoacetate. PMID- 4208529 TI - New streptococcal serotypes causing pyoderma and acute glomerulonephritis types 59,60, and 61. AB - Three new streptococcal M serotypes, types 59, 60, and 61; have been described. They were first isolated from patients with pyoderma and acute glomerulonephritis (AGN), seen during epidemiological studies in Alabama. A possible antigenic relationship between types 59 and 61 was suggested by their T-agglutination reactions; a more specific T antiserum prepared for type 59 was useful in separating these two types, as well as other strains known to share T antigens 11, 12, and 5/27/44. On the basis of precipitin tests, a common antigenic determinant among types 59, 61, and 49 was suggested. This is of interest in view of the relation between these types and AGN. Type 59 has been relatively more widespread in distribution than type 61, but neither have been related to epidemic AGN. Type 60, first identified as "T-4," thus being related to previously described M types which share this antigen, is of great interest in terms of the epidemiology of AGN. Most strains in our collection were recovered from patients with pyoderma and AGN or from their infected siblings. Recently, the type was found to be prevalent among patients with pyoderma and AGN seen in Trinidad. Data reported in relation to these new types further illustrate the dichotomy in M serotypes common to pyoderma and AGN on the one hand and those types found in collections of patients with pharyngitis on the other hand. The high rate of non-M-typable streptococci among pyoderma collections, encountered earlier, is best explained by lack of suitable reference antisera available for prevalent pyoderma serotypes. PMID- 4208530 TI - Bacterial clearance and endocarditis in American opossums. AB - The American opossum is the only experimental animal that regularly develops bacterial endocarditis spontaneously. There was no relation between the ability of opossums to clear bacteria from the bloodstream and the subsequent development of endocarditis. PMID- 4208531 TI - Suppression of growth of Ehrlich ascites tumor cells in mice by trehalose-6,6' dimycolate (cord factor) and BCG. AB - Growth of Ehrlich ascites tumor cells in mice pretreated with cord factor was compared to growth of the tumor cells after pretreatment with Calmette-Guerin bacilli. Growth of Ehrlich ascites cells was strongly inhibited in the peritoneal cavities of mice pretreated with 80 mug of cord factor. The median survival time of the animals was prolonged (70 versus 17 days), and 40% of the mice survived more than 90 days. Tumor suppression was still detectable 36 days after administration of cord factor. The effect of cord factor was local. Comparable results were obtained with living or killed Calmette-Guerin bacilli. The results are discussed. PMID- 4208532 TI - Activity of carbenicillin and ticarcillin against Pseudomonas aeruginosa compared by paired in vitro tests. PMID- 4208533 TI - Experience with low temperature storage of bacteria and fungi. PMID- 4208535 TI - Total synthesis of bisnorpenicillin V. PMID- 4208534 TI - [LD 50 in mice as a measure of virulence for Pseudomonas aeruginosa. Classification and application of preventive measures with specific antisera and carbenicillin]. PMID- 4208536 TI - Antimicrobial activity of 8-deazafolic acid. PMID- 4208538 TI - [Study of clinical dosimeter IDMD-1 in the beams of electron and electromagnetic radiations with energy from 5 to 42 MeV]. PMID- 4208537 TI - [Prophylaxis against osteoporosis in corticosteroid therapy with sodium fluoride (author's transl)]. PMID- 4208539 TI - Tetrathionate broth as a medium for simultaneous demonstration of Salmonella and Pseudomonas aeruginosa. PMID- 4208540 TI - [Listeria monocytogenes isolated from animals in Sweden during 1958-1972]. PMID- 4208541 TI - Polychlorinated biphenyl toxicity to Japanese quail as related to degree of chlorination. PMID- 4208542 TI - Differences in response of caged White Leghorn layers to various polychlorinated biphenyls (PCBs) in the diet. PMID- 4208543 TI - Surface changes in the epicardium of chickens fed polychlorinated biphenyls. PMID- 4208544 TI - Selection for body weight at eight weeks of age. 13. Fecundity. PMID- 4208545 TI - Transplantation of posterior polar plasm in Drosophila. Induction of germ cells at the anterior pole of the egg. AB - In Drosophila melanogaster the primordial germ cells are normally formed at the posterior tip of the egg during the preblastoderm stage. In order to determine whether the posterior polar plasm is capable of inducing the formation of primordial germ cells in another region of the embryo, portions of this cytoplasm were transferred from wild-type embryos of the early cleavage stage to the anterior tip of mwh e embryos of the same age. At various times after the injection (15-200 min), embryos were fixed for histological analysis. Alternating thick and thin sections were examined for the presence of experimentally induced pole cells. In more than half of the embryos analyzed in this way, one to six cells were found containing the polar granules as well as round nuclear structures, both of which are characteristic of normal pole cells and are not present in blastoderm cells. In order to determine whether these "pole cells" function normally, i.e., develop further into germ cells, the cells induced at the anterior tip of mwh e blastoderm embryos were introduced into the posterior region of y w sn(3) hosts of the same age. The flies resulting from these embryos were mated to y w sn(3) partners. In addition to the expected y w sn(3) progeny, wild-type flies heterozygous for mwh e and, therefore, descended from the experimentally induced pole cells were found in 4% of the crosses. Such flies did not appear in the control experiments after transfer of normal anterior cells from noninjected blastoderm embryos. These results demonstrate that the posterior polar plasm can be transferred to the anterior tip of the embryo and that in this presumptive somatic region it still retains its capacity to determine the formation of the primordial germ cells. PMID- 4208546 TI - A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. AB - Dialyzed serum from clotted monkey blood ("blood serum") promotes the proliferation of monkey arterial smooth muscle cells in culture, but dialyzed serum prepared from recalcified platelet-poor plasma ("plasma serum") is much less effective. Addition of platelets and calcium to platelet-poor plasma increases the activity of plasma serum to the same level achieved with blood serum. Furthermore, addition to plasma serum of a platelet-free supernatant prepared by exposing purified platelets to thrombin also stimulates the proliferation of smooth muscle cells. Thus, much of the growth-promoting activity of dialyzed serum is directly or indirectly derived from platelets. This finding has important implications for the response of arteries to localized injury and provides a key to further understanding of the role of factors derived from blood serum in promoting cell proliferation in vitro. PMID- 4208547 TI - Unequal mitotic sister chromatin exchange as the mechanism of ribosomal RNA gene magnification. AB - It is hypothesized that magnification of the gene coding for ribosomal RNA occurs by unequal mitotic sister chromatid exchange on the basis of five different lines of evidence. These are: (1) rDNA magnification occurs in mitotically active germ cells; (2) decreases in rDNA redundancy can be genetically produced, a phenomenon termed reduction; (3) magnification and reduction events are reversible and reciprocal; (4) it is possible to generate bb(+) and bb somatic bristle mosaics (bb mutants are partially deficient for rRNA genes); and (5) magnification of bb in a ring X chromosome is reduced. Implications of these results and the unequal sister exchange (USE) hypothesis are discussed. PMID- 4208549 TI - Genetic control of imaginal disc development in Drosophila. AB - Many of the functions required for formation of the imaginal discs of Drosophila melanogaster larvae, from which adult structures are derived, are disc-specific and not required for formation of other larval tissues. Mutants blocked in disc specific functions can produce mature viable larvae, indicating that larval development is not dependent on concomitant disc development. Some of the mutant larvae have no detectable discs (discless mutants), and other have small discs that cannot differentiate into adult structures (small disc mutants). From the results of genetic complementation and mapping experiments with such mutants, it was estimated that the genome of D. melanogaster contains around a thousand complementation groups, or about a fifth of all complementation groups in the genome, that are essential specifically for the development of all the discs. The developmental defects in some of the disc mutants appear to involve autonomous functions of the imaginal cells, and in other mutants functions provided by the larval environment to support disc development. This distinction was made on the basis of two functional tests. The purpose of one of the tests was to detect the presence in young embryos of determined imaginal cells capable of differentiating after transplantation to a wild-type host; the other test measured the capacity of early third-instar larvae to act as hosts for the further development of immature discs transplanted from a wild-type donor. Three discless mutants that were tested in this way appeared to be defective in autonomous functions of the imaginal cells, since the embryos contained no imaginal cells that could be detected in the first test, whereas the larvae, although devoid of discs, showed a normal capacity to support disc development in the second test. One of the small disc mutants tested was defective in a larval rather than an imaginal cell function, since the embryos had a normal complement of functional imaginal cells, whereas the larvae were incapable of supporting disc development. Thus, both types of disc-specific functions are essential for normal disc development. PMID- 4208548 TI - Kinetic evidence for the presence of two prostaglandin receptor sites regulating the activity of intestinal adenylate cyclase sensitive to Escherichia coli enterotoxin. AB - Kinetic behavior most consistent with the presence of two independent, but simultaneously acting, regulatory effector sites for prostaglandins has been presented for adenylate cyclase (EC 4.6.1.1) of rabbit intestinal epithelial cells. One site regulates activation of the catalytic site, while the other site regulates inhibition. A synthetic prostaglandin analogue, 7-oxa-13-prostynoic acid, is recognized at both sites in a concentration-dependent manner. At concentrations of 7-oxa-13-prostynoic acid less than 45 mug/ml, activation is seen, while at higher concentrations, inhibition is seen. Different naturally occurring prostaglandins appear to be site-specific. Prostaglandin E(1) gives only activation of the cyclase, while prostaglandin A(1) gives only inhibition of the activated cyclase. When saturating concentrations of prostaglandin E(1) are used to activate adenylate cyclase, no further activation by 7-oxa-13-prostynoic acid can be elicited, indicating that both molecules activate at the same site. The similarity of inhibition constants for both 7-oxa-13-prostynoic acid and prostaglandin A(1) suggests that the mode of binding is the same for both compounds and that they probably inhibit by acting at the same site. The inhibition by 7-oxa-13-prostynoic acid and by prostaglandin A(1) overrides enzyme activation produced by either Escherichia coli enterotoxin, prostaglandin E(1), or sodium fluoride, suggesting that in intestinal adenylate cyclase this site is the primary regulatory site (i.e., primary allosteric effector site) for enzyme activity. These data suggest that sites exist on adenylate cyclase which would allow prostaglandins to serve as the intracellular messengers by which the cell controls its adenylate-cyclase-mediated response to extracellular stimulation, as with hormones. PMID- 4208550 TI - Evidence for the presence of the toxin-binding protein on the plasma membrane of sugarcane cells. AB - Helminthosporoside is a host-specific toxin produced by Helminthosporium sacchari, both in culture and in infected sugarcane tissue. The susceptibility of any given clone of sugarcane to disease is invariably associated with the presence of a toxin-binding protein. This report presents evidence for the presence of the toxin-binding protein on the plasma membrane of the plant cell. This evidence includes, among others: (1) The protection of susceptible plant tissues by prior treatment with antiserum to the binding protein, (2) the successful pyridoxylation and reduction of the binding protein in vivo followed by its isolation, (3) the reaction of sugarcane cells and free protoplasts with [(3)H]antiserum prepared against the binding protein, and (4) the agglutination of sugarcane protoplast preparations with antiserum to the binding protein. PMID- 4208551 TI - Partial purification of detergent-soluble HL-A antigen and its cleavage by papain. AB - HL-A antigen solubilized with the non-ionic detergent, Brij 99, has been purified to about 50% of homogeneity from a cultured human lymphoblast line. It consists of two nonidentical subunits of 44,000 and 12,000 molecular weight (MW). Upon papain proteolysis the 44,000 MW peptide is converted by at least two cleavages to a 34,000 MW peptide, but the 12,000 MW peptide appears to be unchanged. Concomitantly, the apparent molecular weight in gel filtration chromatography under nondenaturing conditions in the presence of Brij 99 is reduced from 460,000 to 45,000. HL-A molecules produced by direct papain proteolysis of membranes and by papain treatment of purified detergent-soluble HL-A are identical. PMID- 4208553 TI - [Conservative treatment of ulcerative colitis of the large intestine in the light of our observations]. PMID- 4208552 TI - [Hydrogen ion excretion by the kidneys--physiological and clinical aspects (author's transl)]. PMID- 4208555 TI - [Polygraphic characteristics of nocturnal sleep in subjects with familial myoclonus-epilepsy (Unverricht-Lundborg syndrome)]. PMID- 4208554 TI - [Calcitonin and phosphates in osteoporosis: experimental principles]. PMID- 4208556 TI - Tuberculosis survey in East Central State, Nigeria: implications for tuberculosis programme development. PMID- 4208557 TI - Epileptic fits in cysticercosis. PMID- 4208558 TI - Use of sulfadiazine in the prophylaxis of group A meningococcal carriers in Egypt. PMID- 4208559 TI - Pediatric urinary tract infection. Significance of vaginal bacteria. PMID- 4208560 TI - [Results of study of gonococcal sensitivity to penicillin in different cities of the USSR]. PMID- 4208561 TI - [Rare case of multiple neurofibromatosis]. PMID- 4208562 TI - [Prevention of Rh-isoimmunization in connection with spontaneous abortion and interruption of pregnancy]. PMID- 4208563 TI - e1morphometric examinations of the placenta in morbus haemolyticus neonatorum (Mhn). PMID- 4208564 TI - [Biochemistry of fetal distress]. PMID- 4208565 TI - A simplified and rapid direct method for the determination of triiodothyronine in human serum. PMID- 4208566 TI - [Leishmaniasis in Tunisia. Sero-immunological survey about the frequency of infestation (author's transl)]. PMID- 4208568 TI - Scanning electron microscopy on the distribution of the minute blood vessels in the thyroiod gland of the dog, rat and rhesus monkey. PMID- 4208567 TI - Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis. AB - When an actively growing culture of the H37Ra strain of Mycobacterium tuberculosis was exposed to isoniazid at a concentration of 0.5 mug/ml, the cells began to lose their ability to synthesize mycolic acids immediately. After 60 min, the cells had completely lost this ability. The synthesis of the three mycolate components-alpha-mycolate, methoxymycolate, and beta-mycolate-was inhibited. The viability of the isoniazid-treated cells was unaffected up to about 60 min of exposure, after which time there was a gradual decline in the viability to about 18% after 180 min. Correspondingly, growth of the drug-treated cells slowed down and stopped after 24 hr. The inhibition of the synthesis of mycolic acids was reversible if the drug was removed before the loss of viability set in. Incubation of the viable cells in the absence of the drug for 24 hr restored the mycolate synthesis. These results strongly suggest that the inhibition of the synthesis of the mycolic acids is closely associated with the primary mechanism of action of isoniazid on the tubercle bacilli. The sequence of events which leads to the loss of viability of cells exposed to isoniazid is described. PMID- 4208569 TI - Activation of prephenoloxidase. 3. Release of a peptide from prephenoloxidase by the activating enzyme. PMID- 4208570 TI - Dissociation of tetanus neurotoxin into two polypeptide fragments. PMID- 4208571 TI - Enzymatic breakdown of tetanus toxin. PMID- 4208572 TI - Chemical modification of the tryptophan residue in toxin B from the venom of the Indian cobra. PMID- 4208573 TI - Quantitative aspects of ribosomal RNA synthesis during ovarian development in two mutants of Drosophila melanogaster. PMID- 4208574 TI - The pathology of experimental lead encephalopathy in the baboon (Papio anubis). PMID- 4208575 TI - [Occurrence of children's tuberculosis in the East Bohemian region during the years 1960-1970]. PMID- 4208576 TI - [Warning on the possibility of diphtheria infection in pediatric nurses on children's departments]. PMID- 4208577 TI - Delta-aminolevulinic acid synthetase activity in normal human bone marrow and in patients with idiopathic sideroblastic anemia. PMID- 4208578 TI - Regulatory link between lactate dehydrogenase and biosynthesis of porphyrin and heme in microorganisms. PMID- 4208579 TI - Effect of oxygen on heme and cytochrome content in some facultative bacteria. PMID- 4208580 TI - Role of oxygen in the late steps of heme synthesis in pseudomonads and Escherichia coli. PMID- 4208581 TI - Comparison of porphyrin and heme biosynthesis in various heterotrophic bacteria. PMID- 4208582 TI - [Metabolites of microorganisms. 130. Synthesis of delta-N-hydroxy-L-arginine]. PMID- 4208583 TI - Peptic digestion of pig IgM. PMID- 4208584 TI - Equine anti-hapten antibody. 8. Isoelectric fractions of IgM and 7S anti-lactose antibody. PMID- 4208585 TI - Does J chain mediate the combination of 19S IgM and dimeric IgA with the secretory component rather than being necessary for their polymerization? PMID- 4208586 TI - The membranes of the basal labyrinth in kidney cells of the stickleback, Gasterosteus aculeatus, studied in ultrathin sections and freeze-etch replicas. PMID- 4208588 TI - Differentiation in breast cancer. PMID- 4208589 TI - Spermatogenesis in pharate adult testes of Drosophila in tissue cultures without ecdysones. PMID- 4208591 TI - [Experimental salmonellosis in monkeys. 2. Observations on bacillary invasion and localization of antibody in the mucous membrane by immunofluorescence method]. PMID- 4208590 TI - [Experimental salmonellosis in monkeys. 1. Studies on immunoglobulins of monkeys and their isolation]. PMID- 4208587 TI - Clinical value of tumour-associated antigens. PMID- 4208593 TI - [Smallpox]. PMID- 4208592 TI - [Causative agent of "Hyuganetsu" disease. 11. Characteristics of rickettsia-like organisms isolated from metacercaria of Stellantchasmus falcatus]. PMID- 4208594 TI - [Study on the distribution of various types of group A hemolytic streptococcus. Annual changes and regional difference in distribution of group A streptococci isolated from scarlet fever patients from April 1969 to March 1973]. PMID- 4208595 TI - [Distribution of group A hemolytic streptococci (1969-70)]. PMID- 4208596 TI - [Result of isolation of pharyngeal hemolytic streptococci in children of a primary school using a new selective enriched medium (Q-media)]. PMID- 4208597 TI - [Transition of drug sensitivity of group A streptococci in the last 6 years (1967 72)]. PMID- 4208598 TI - [Epidemiological study on scarlet fever]. PMID- 4208599 TI - [Scarlet fever in Sapporo City]. PMID- 4208600 TI - [Serological study on scarlet fever]. PMID- 4208601 TI - [Relationship between anti-streptokinase levels and hemolytic streptococcal types in scarlet fever]. PMID- 4208602 TI - [Normal value of ASK]. PMID- 4208603 TI - [Antigenic analysis of group A, C, and G hemolytic streptococci by precipitin reaction in gels and immunoelectrophoresis]. PMID- 4208604 TI - [Antibiotic therapy of scarlet fever]. PMID- 4208605 TI - [On the pituitary TSH response to different dosage of thyrotropin-releasing factor (TRF) (author's transl)]. PMID- 4208606 TI - Palindromes in chromosomes. PMID- 4208607 TI - The structure of psi DNA. PMID- 4208608 TI - Vaginal flap incision for urethral diverticulectomy. PMID- 4208609 TI - Nocardiosis of the testis. PMID- 4208610 TI - [Electron microscopic observations on endocrine and exocrine cells of the pancreas]. PMID- 4208612 TI - Letter: The use of nebulized intal in asthma. PMID- 4208611 TI - Serum folic acid levels and pregnancy in South Australia. A study of the factors associated with low serum folic acid levels with particular reference to racial groups and lactation. PMID- 4208614 TI - [Toxicity of ketamine]. PMID- 4208613 TI - Rapid grouping of streptococci by immunoelectroosmophoresis. PMID- 4208615 TI - [The effect of preparations of different proteinases on calf dermis collagen]. PMID- 4208616 TI - The establishment of rumen ciliate protozoa in sheep fed on whole barley to appetite. PMID- 4208617 TI - Autoradiographic evidence for the occurrence of cell fusion cultures of Theileria infected bovine lymphoid cells. PMID- 4208618 TI - An investigation of the association between circulating antibody levels and systemic anaphylactic sensitivity in cattle. PMID- 4208619 TI - Capsular and somatic antigens of Pasteurella multocida, types B and E. PMID- 4208621 TI - [Diverticula of the digestive tract]. PMID- 4208620 TI - Histochemistry of enzymes involved in the synthesis and breakdown of glycogen in the junctional zone of the rat's placenta. PMID- 4208622 TI - [Duodenal diverticula. Surgical treatment]. PMID- 4208623 TI - [Greater attenuation of the virulence of Brucella abortus 19 with preservation of its immunogenicity]. PMID- 4208624 TI - [Preventive and curative tuberculosis immunization with antigenic fractions of M. tuberculosis]. PMID- 4208625 TI - [Study of 6 strains of Mexican Trypanosoma cruzi]. PMID- 4208626 TI - Factor XII-induced fibrinolysis: studies on the separation of prekallikrein, plasminogen proactivator, and factor XI in human plasma. PMID- 4208627 TI - [Multiple forms of the microbial aminopeptidase that hydrolyzes leucyl-glycyl glycine]. PMID- 4208629 TI - Uses of epidemiology in housing programmes and in planning human settlements. Report of a WHO Expert Committee on Housing and Health. PMID- 4208628 TI - [Synthesis and utilization of water-soluble antigen and antibody derivatives]. PMID- 4208630 TI - [Latent periods of evoked responses to stimulation of the hippocampus in Macacus rhesus monkeys and rabbits]. PMID- 4208631 TI - Retinal effects of a multiple-pulse laser. PMID- 4208632 TI - Metabolism of two valence states of inhaled antimony in hamsters. PMID- 4208633 TI - [119 cases of traumatic epilepsy]. PMID- 4208634 TI - Immune response to Listeria monocytogenes in rabbits and humans. AB - Rabbits were immunized with listeria antigens, staphylococcus antigen, or with both, and the course of their immune response was monitored. Antibodies to Listeria and Staphylococcus were produced in both immunoglobulin M (IgM) and immunoglobulin G (IgG) classes in response to inoculation with the specific antigen. Cross-responses occurred in rabbits injected only with Listeria or only with Staphylococcus, as well as in rabbits injected with both antigens. L. monocytogenes serotype 4d appeared to be immunologically distinct from L. monocytogenes serotype 2 and its cross-reaction with S. aureus. Human sera from bacteriologically confirmed cases of listeriosis were examined to determine the nature of the immunological response of man to Listeria. In the sera studied, IgM was the predominant antibody produced to Listeria, whereas cross-reactions with Staphylococcus were observed in both the IgM and the IgG antibody classes. PMID- 4208635 TI - Resistance to gonorrhea possibly mediated by bacterial interference. AB - Two men with no prior history of urethritis failed to develop gonorrhea after sexual exposures to women with genital gonococcal infection. Usual methods of prophylaxis, such as antibiotics or condoms, were not employed. The aerobic bacterial flora of these men's urethras consisted of several bacteria, some of which inhibited the in vitro growth of Neisseria gonorrhoeae. The hypothesis is suggested that bacterial interference may have played a role in protecting these men from gonorrhea. PMID- 4208636 TI - Rapid detection of Clostridium botulinum toxin by capillary tube diffusion. AB - A micro capillary agar-gel diffusion system for the detection of botulinal toxin in foods and cultures was developed and evaluated. Toxins types A, B, and E, produced in culture broth with and without added trypsin, and type E toxin, produced in inoculated canned clams, were tested with this system and with the mouse bioassay procedure. With nontrypsinized toxin, the capillary diffusion system detected as little as 100 minimal lethal doses (MLD) per ml but was effective only at higher levels, 10(6) to 1.5 x 10(7) MLD/ml, when used with trypsinized toxin. The inability to detect lower levels of trypsinized toxin was due to thioglycolate present in the medium used to produce toxin. Evidently, trypsinization of toxin produces polypeptides still held together by disulfide bonds. Cleavage of these bonds by reduction with thioglycolate reduces the sensitivity of the capillary method. Trypsinized toxin produced in broth without thioglycolate was detected as readily as nontrypsinized toxin. Toxin was detected in canned clams containing as low as 100 MLD/ml. No cross-reactions were observed with type E toxin and types A and B antitoxins. Extensive studies using the capillary method for detecting types A and B toxins were not performed; however, a suspected sample of commercially canned mushrooms gave a positive type B reaction but not a type A reaction. This typing was confirmed later by the mouse bioassay. Toxin was present at a level of 100 MLD/ml. The procedure developed may prove useful as a rapid screening method for the detection of botulinal toxin in foods, with final identification made by using the mouse bioassay. PMID- 4208637 TI - NYC medium for simultaneous isolation of Neisseria gonorrhoeae, large-colony mycoplasmas, and T-mycoplasmas. AB - NYC medium, primarily designed for isolation of pathogenic Neisseria, also readily supports the growth of large-colony mycoplasmas and T-mycoplasmas. When compared with A-3 agar medium and PPLO agar in clinical field trials, NYC medium performed equally as well as these mycoplasma-specific media in providing recovery of Mycoplasma species from female genital specimens. The transparent, highly-selective NYC medium permits direct, microscopic observation and presumptive identification of mycoplasmas, as well as Neisseria gonorrhoeae, without interference from contaminating saprophytes. As a single medium it can therefore be doubly useful in the diagnosis of gonorrhea and in the recognition of active or asymptomatic mycoplasma infections. Used in gonorrhea screening programs, the medium can be valuable in establishing the frequency of association of mycoplasmas with urogenital tract infection. PMID- 4208638 TI - Retention of 14C-labeled tuberculin purified protein derivative in the skin of sensitized and nonsensitized animals. AB - Tuberculin purified protein derivative labeled with (14)C ([(14)C]PPD) with a biological potency equivalent to the International Standard for tuberculin PPD was used to study the retention of tuberculin PPD in the skin of sensitized and nonsensitized animals. We found that [(14)C]PPD was almost entirely cleared from the skin test site during the first 18 to 24 h after injection and that when approximately 5% of the initial concentration of [(14)C]PPD was present in the skin test site, the size of the tuberculin skin reaction in sensitized guinea pigs was at its maximum. Furthermore, the addition of 5 or 50 mug of Tween 80 per ml to a solution of PPD did not change either the rate of clearance of PPD from the skin test sites of sensitized guinea pigs or the size of the tuberculin skin reactions. There was no difference in the rate of clearance of [(14)C]PPD from the skin test sites between sensitized and nonsensitized guinea pigs and between guinea pigs of different age. However, there was a significant difference in the rate of clearance of [(14)C]PPD between the guinea pig and the mouse. Finally, the percentage of [(14)C]PPD retained in the site of injection at 24 h was in the neighborhood of 5% of the initial concentration of the solution of PPD injected. The significance of these phenomena is discussed. PMID- 4208639 TI - Aflatoxin-producing strains of Aspergillus flavus detected by fluorescence of agar medium under ultraviolet light. AB - The fluorescence method of detecting aflatoxin-producing strains of Aspergillus flavus and related species utilizes the ultraviolet-induced fluorescence of aflatoxin produced in a modified Czapek's solution agar containing corn steep liquor, HgCl(2), and (NH(4))H(2)PO(4) instead of NaNO(3). The presence of aflatoxin is confirmed by thin-layer chromatography of CHCl(3) extracts of the fluorescing agar. PMID- 4208640 TI - Plaque assay of rickettsiae in a mammalian cell line. AB - Clear-cut and repeatable plaque assays were obtained for three rickettsiae of the spotted fever group (Rickettsia rickettsi, R. conori, and R. montana) in Vero cells used in a manner similar to that for arboviruses. In addition, three typhus group agents (R. typhi, R. canada, R. prowazeki) induced plaques in these cells. In preliminary tests Coxiella burneti (Nine Mile strain) failed to produce plaques. Comparable results were obtained in plastic flasks and plastic culture trays incubated in ambient air with or without addition of N-2-hydroxyethyl piperazine-N'-2-ethanesulfinic acid buffer. Larger and more well defined R. rickettsi plaques were produced when cultures were overlaid with Leibovitz (L15) medium than with either medium 199 or Eagle medium. Phosphate-buffered saline containing bovine plasma albumin (fraction V), in contrast to brain heart infusion broth, as a diluent for preparing inocula consistently permitted development of larger and more numerous plaques with three agents: R. rickettsi, R. conori, and R. montana. When R. rickettsi and R. typhi were assayed in parallel in primary chicken embryo cultures and Vero cells, comparable results were obtained, but with R. canada results in Vero cells were superior. In contrast, R. prowazeki produced inconsistent results in Vero cells. PMID- 4208641 TI - Epidemiological tracing of Pseudomonas aeruginosa: antibiogram and serotyping. AB - The spread of a particular strain of Pseudomonas aeruginosa through a pediatric burn unit was monitored using serological typing and antibiotic susceptibility data. PMID- 4208642 TI - Raman spectroscopy in vivo: evidence on the structure of dipicolinate in intact spores of Bacillus megaterium. PMID- 4208643 TI - Anomalous molecular weights to proteases in gel chromatography. PMID- 4208644 TI - Ribsome and messenger specificity in protein synthesis by bacteria. PMID- 4208645 TI - Exploitation of the oxygen enhancement ratio in clinical practice. PMID- 4208646 TI - Effects of radiation dose-rate from protracted, continuous irradiation to ultra high dose-rates from pulsed accelerators. PMID- 4208647 TI - Cortical motor representation of the laryngeal muscles in Macaca mulatta. PMID- 4208648 TI - The postnatal development of antigens on mouse brain cell surfaces. PMID- 4208649 TI - Metabolism of acid-soluble nucleotides in starved-refed-synchronized Tetrahymena pyriformis GL. PMID- 4208650 TI - The organization and gross mineralization patterns of the collagen fibres in Sharpey fibre bone. PMID- 4208651 TI - Genetic, cytological, and ultrastructural characterization of a temperature sensitive lethal in Drosophila melanogaster. PMID- 4208652 TI - Radioimmunoassay of rat parathyroid hormone in serum and tissue extracts. PMID- 4208653 TI - Persistent abnormalities in pituitary function following neonatal thyrotoxicosis in the rat. PMID- 4208654 TI - Stimulation of prolactin release in vivo by thyrotropin-releasing hormone (TRH) through direct action on the ectopic rat pituitary. PMID- 4208655 TI - Neurological and psychomotor functions in children with an increased lead burden. AB - Fifty-eight children with an increased lead burden underwent comprehensive investigations and were reevaluated 1(1/2) to 3 years later. Of these children 23 27% were noted to have minor neurological dysfunction and various forms of motor impairment during each evaluation. While the initial psychological assessment revealed low average mental abilities in the majority of children, during follow up examination a significant increase in certain areas of intellectual functioning was observed. PMID- 4208656 TI - Biochemical and toxicological response of infant baboons to lead driers in paint. AB - In an effort to define the toxicology and disposition of lead compounds that presently exist in paint (i.e., organic driers), a controlled dose feeding study was initiated early this year with the use of 28 infant baboons as experimental animals. The infant baboon, established as a metabolic model for a child ingesting lead, will be used to determine the adequacy of present as well as recently recommended limitations for lead in paint to assure protection from this potential source of lead exposure. To accomplish this goal, research has been designed to determine basic dose-response relationships in animals ingesting constant daily doses of a dried paint, a lead octoate drier, and lead acetate. Doses for these compounds have been chosen to cover a broad range of concentrations including that recommended by the American Academy of Pediatrics from the maximum daily permissible lead ingestion, and associated estimates of paint intake by children with pica. PARAMETERS OF METABOLIC RESPONSE FOR EACH LEAD COMPOUND, INCLUDE: general clinical surveillance, lead concentrations in blood, urine and feces, erythrocytic delta-aminolevulinic acid dehydratase and free erythrocytic porphyrin. The response of several of these measures of lead exposure as a function of time will be discussed for each compound at the several dose levels administered. PMID- 4208657 TI - Experimental acute lead encephalopathy in the juvenile rhesus monkey. AB - Lead subacetate (0.5g) and 1000 units of vitamin D were given three times a week to four newly-weaned rhesus monkeys. In addition, two animals received only the vitamin D. The poisoned animals had an increase in the urinary excretion of delta aminolevulinic acid, an elevated content of lead in the blood, and a fall in hemoglobin concentration. Between 6 and 18 weeks the animals suddenly developed ataxia, nystagmus, generalized weakness, and convulsions. At this time the animals were killed by perfusion of fixative and the brain prepared for light and electron microscopic studies. Definite morphological evidence of disease was confined to the central nervous system, except for one animal which showed the characteristic renal inclusions of lead poisoning. All animals showed PAS positive globules associated with blood vessels and an exudative edema involving the white matter of the cerebral hemispheres and cerebellum. Ultra-structurally, this appeared as a granular precipitate within an expanded extracellular space. Alterations of nerve fibers were not seen in the white matter but axonal swelling was observed in the cerebral cortex. The perikaryon and neuropil appeared normal. The control animals showed no significant cerebral changes. PMID- 4208659 TI - Influence of oxygen and pH on plating efficiency and colony development of WI-38 and Vero cells. PMID- 4208658 TI - Pathobiological and behavioral effects of lead intoxication in the infant rhesus monkey. AB - When infant rhesus monkeys were exposed to lead via the addition of lead acetate (0.5-9 mg/kg body weight) to their formula or by the consumption of lead particles from lead-based surrogate mothers, they developed symptoms of lead intoxication within 6 weeks. Seizures, muscular tremors, and altered social interaction were the predominant changes. Visual impairment was also apparent in the more severely affected animals. In the animals showing obvious symptoms lead levels varied between 300 to 500 mug/100 ml of blood. Even in those animals having blood lead levels below 100 mug, hyperactivity and insomnia were observed. When the exposure to lead was eliminated, seizures subsided and visual impairment was reduced; however, the abnormal social interaction persisted. These animals also experienced a gradual decline in hematocrit and hemoglobin values during the period of examination. Liver and kidney biopsies obtained from these lead-exposed animals revealed characteristic intranuclear inclusions.When adolescent and adult monkeys were exposed to doses of lead acetate similar to those employed in the infant experiments, lead levels in excess of 200 mug/100 ml of blood were recorded. However, there were no obvious behavioral abnormalities observed. There were, however, numerous lead inclusion bodies in kidney biopsy specimens from these animals. These data suggest that, like man, the infant nonhuman primate is much more susceptible to lead intoxication than is the adult. The clinical and behavioral changes recorded in these infant rhesus monkeys suggest their use as an experimental model to evaluate lead intoxication. PMID- 4208660 TI - Phase-dependent lobopodial contact paralysis. PMID- 4208661 TI - D-ribulose 1,5-diphosphate carboxylase from Rhodospirillum rubrum. I. Levels, purification, and effects of metallic ions. PMID- 4208662 TI - D-ribulose 1,5-diphosphate carboxylase from Rhodospirillum rubrum. II. Quaternary structure, composition, catalytic, and immunological properties. PMID- 4208663 TI - On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells. PMID- 4208665 TI - Purification and properties of flagellar outer doublet tubulin from Naegleria gruberi and a radioimmune assay for tubulin. PMID- 4208664 TI - A comparison of the L-arabinose- and D-galactose-binding proteins of Escherichia coli B-r. PMID- 4208666 TI - Meningococcal conjunctivitis. Report of a case. PMID- 4208667 TI - Development of knowledge of unity of tuberculosis and of the portals of entry of tubercle bacilli. PMID- 4208668 TI - A method of freeze-drying and fixing bacterial cultures for electron microscopy. PMID- 4208669 TI - Erroneous Model S Coulter Counter values on patients undergoing parenteral nutrition with intravenous lipid emulsions. PMID- 4208670 TI - [Lipid biosynthesis by actinomycetes cultured on different media]. PMID- 4208671 TI - [Electrokinetic properties of the cells of microorganisms and their taxonomy]. PMID- 4208672 TI - [Ultrastructure and some biological properties of Bacillus subtilis phage AR7]. PMID- 4208674 TI - Problems in geriatrics. PMID- 4208673 TI - [Methods of working with bacterial microcultures]. PMID- 4208675 TI - Nursing procedures: you'd be amazed at what they cost. (And maybe you're not to blame). PMID- 4208676 TI - Cromolyn--metaproterenol. PMID- 4208677 TI - The effect of prostaglandin E2 on the rhesus monkey pupil. PMID- 4208678 TI - Effects of sequential treatment with estradiol and PGF2alpha on the length of the primate menstrual cycle. PMID- 4208679 TI - [Functional exploration of the hypothalamic-pituitary-adrenal cortex system in the chronic form of Chagas' disease]. PMID- 4208680 TI - [Lipids and atherosclerosis]. PMID- 4208682 TI - Platelet aggregation induced by procollagen. PMID- 4208681 TI - Biosynthetic activities in normal and pathological platelet populations. PMID- 4208683 TI - Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) deficiency: immunologic studies on the mutant enzyme. PMID- 4208684 TI - Immunological studies of hypoxanthine-guanine phosphoribosyltransferase in Lesch Nyhan syndrome. PMID- 4208685 TI - Unstable HPRTase in subjects with abnormal urinary oxypurine excretion. PMID- 4208686 TI - Human hypoxanthine-guanine phosphoribosyltransferase (HGPRT): purification and properties. PMID- 4208687 TI - The enzymatic conversion of cis-(14C)phytofluene, trans-(14C)phytofluene, and trans-zeta-(14C)carotene to poly-cis-acyclic carotenes by a cell-free preparation of tangerine tomato fruit plastids. PMID- 4208688 TI - Chemical modification studies of chloroplast membranes. Water oxidation inhibition by diazonium-benzenesulfonic acid. PMID- 4208689 TI - tRNA methylases from HeLa cells: purification and properties of an adenine-1 methylase and a guanine-N2-methylase. PMID- 4208691 TI - [Kinetic study of the metabolic effects of a blood meal in Aedes aegypti]. PMID- 4208690 TI - L-Rhamnulose 1-phosphate aldolase of Escherichia coli. The role of metal in enzyme structure. PMID- 4208692 TI - [Repercussions of hypothalamic deafferentiation combined with optic nerve section on the photosexual reflex in the quail (Coturnix coturnix japonica)]. PMID- 4208693 TI - [The urine of the lactating female contains a pheromone stimulating aggression in small groups of female mice]. PMID- 4208694 TI - [Effect of synthetic LH-FSH releasing hormone and hypothalamic extracts of the carp on in vivo gonadotropic hormone secretion in the carp (Cyprinus carpio L.)]. PMID- 4208695 TI - [Transformation of phospholipids of group A streptococcus L forms by the action of human serum complement]. PMID- 4208696 TI - [Detection of viral antigens of Marek's disease using immunosera conjugated with peroxidase]. PMID- 4208697 TI - [Arthrogenic activity of various mycobacterial preparations]. PMID- 4208698 TI - [Prolongation, by interferon, of the survival of skin grafts in the mouse]. PMID- 4208699 TI - Antigenic analysis of raw soybean: variation of host response during prolonged immunization. PMID- 4208700 TI - Purification and characteristics of pyocin B39. I. General properties. PMID- 4208701 TI - Isolation of Toxoplasma during unsuccessful attempts to isolate Rickettsiae from swine and rodents in Taiwan. PMID- 4208702 TI - Bacterial meningitis: current status of vaccines against the meningococcus and hemophilus influenzae type B. PMID- 4208703 TI - A review of brucellosis in the horse. PMID- 4208704 TI - Editorial: Diet and diverticular disease. PMID- 4208705 TI - Collaborative study of the determination of polychlorinated biphenyls in paperboard. PMID- 4208706 TI - Manual microbiological turbidimetric analysis of chlortetracycline in feeds. PMID- 4208707 TI - Direct chromatography of some N-methylcarbamate pesticides. PMID- 4208708 TI - Confirmation of pesticide residue identity. VII. Solid matrix derivation procedure for the simultaneous confirmation of heptachlor and endrin residues in the presence of large quantities of polychlorinated biphenyls. PMID- 4208709 TI - Colorimetric method for estimation of carbaryl and its residues on grains. PMID- 4208710 TI - Determination of carbaryl in pesticide formulations and fertilizers by high pressure liquid chromatography. PMID- 4208711 TI - Human leukemia cell antigens: serologic characterization with xenoantisera. PMID- 4208712 TI - Human leukemia antigens: partial isolation and characterization. PMID- 4208713 TI - Differential analysis of cyclocytidine, 1-beta-D-arabinofuranosylcytosine, and 1 beta-D-arabinofuranosyluracil by ultraviolet spectophotometry. PMID- 4208714 TI - Effect of Brucella abortus infection (vaccine strain 19BA) on Rauscher leukemia virus and L1210 leukemia in mice. PMID- 4208716 TI - The problem of the alcohol-dependent individual. PMID- 4208715 TI - Effect of oral contraceptives on the mammary glands of Rhesus monkeys: a preliminary report. PMID- 4208717 TI - Editorial: Plastic surgical treatment of basal cell skin cancer. PMID- 4208718 TI - Improved therapy for Vietnam acquired vivax malaria. PMID- 4208719 TI - A survey to assess potential human disease hazards along proposed sea level canal routes in Panama and Colombia. V. Arbovirus infection in non-human vertebrates. PMID- 4208720 TI - Host factors in human frostbite. PMID- 4208721 TI - Serum uric acid and cholesterol variability for men aboard a Polaris submarine. PMID- 4208722 TI - Medical evacuations for selected chronic diseases: USARPAC, 1970-71. PMID- 4208723 TI - The effect of premedication and angiography on arterial blood gases. PMID- 4208724 TI - Meningococcemia presenting as septic arthritis: case report. PMID- 4208725 TI - Cerebral vasospasm: a review. PMID- 4208726 TI - The Alcohol Rehabilitation Unit, National Naval Medical Center, Bethesda. PMID- 4208727 TI - [Analysis of the course of spa treatment. Results of longitudinal investigations in different places (author's transl)]. PMID- 4208728 TI - [The absorption of terpenes from bath additives (author's transl)]. PMID- 4208729 TI - [Results of a pilot study by the Kneipp-Bund on the prophylaxis of coronary heart diseases (author's transl)]. PMID- 4208730 TI - [Psychological motives for smoking (author's transl)]. PMID- 4208731 TI - [The treatment of smoking (author's transl)]. PMID- 4208732 TI - [Medical support of nicotine withdrawal. Report on a double blind trail in over 5000 smokers (author's transl)]. PMID- 4208733 TI - [5 yearss of the Bad Mayheim nicotine withdrawal therapy and non-smoker's training (author's transl)]. PMID- 4208734 TI - [Non-smoking training (author's transl)]. PMID- 4208735 TI - [Change of diet as an aid to stopping smoking (author's transl)]. PMID- 4208736 TI - [Contribution to the Sjogren-Larsson syndrome (author's transl)]. PMID- 4208737 TI - [Placebo-effect of aids for stopping of smoking]. PMID- 4208738 TI - [Psychologic studies after administration of Dogmatil]. PMID- 4208739 TI - Preparation of mono-specific antisera against staphylococcal alpha- and beta hemolysin by using agar gel precipitates as immunogen. PMID- 4208740 TI - Reserpine in experimental cerebral edema: further observations. PMID- 4208741 TI - Pesticide residues in total diet samples. VI. PMID- 4208742 TI - Recurrent pneumomediastinum in diabetic ketoacidosis. PMID- 4208743 TI - Letter: Anticonvulsant therapy in cerebral injuries. PMID- 4208744 TI - [Hydergine in the treatment of cerebral circulatory disorders, including arteriosclerosis (author's transl)]. PMID- 4208745 TI - Temporally-related stimulus properties of delta9-tetrahydrocannabinol in monkeys. PMID- 4208746 TI - [Plasma TSH and circulating thyroid hormone (T3 and T4) levels in patients with goiter and endemic cretinism]. PMID- 4208747 TI - Intrathoracic vagus nerve tumours. PMID- 4208748 TI - The identification of rumen ciliates from eastern Bos taurus. PMID- 4208749 TI - Histocompatibility-linked immune-response genes in the rhesus monkey. PMID- 4208750 TI - Beneficial influence of limited histocompatibility of bone marrow grafted to unrelated rhesus monkeys preconditioned with x-ray and ALS. PMID- 4208751 TI - Further studies of tissue-typing sera in baboons. PMID- 4208753 TI - Further studies with HL-A reagents raised in primates: analysis of the human HL A2-HL-A28 cross-reaction. PMID- 4208754 TI - Characterization of lymphocyte subpopulations of nonhuman primates separated by free-flow electrophoresis. PMID- 4208752 TI - Isolation of baboon xenogeneic histocompatibility antigens. PMID- 4208756 TI - Immunopathogenesis of dengue infection in the rhesus monkey. PMID- 4208757 TI - Transfer of delayed hypersensitivity to nonsensitive human leukocytes with rhesus monkey lymphoid RNA extracts. PMID- 4208758 TI - Studies on rhesus-monkey nondialyzable and dialyzable transfer factors. PMID- 4208759 TI - [Chronic occlusion of arteries in the extremities and long-term anticoagulant therapy. Studies on 140 men with several angiographies]. PMID- 4208755 TI - Use of nonhuman primates for assaying tumorigenicity of viral-vaccine cell substrates. PMID- 4208760 TI - [Comments on the article "Treatment of a patient with severe injury and erroneous transfusion of massive dose of group heterologous blood"]. PMID- 4208762 TI - [Method of applying a biliary-gastric anastomosis]. PMID- 4208761 TI - [Surgical treatment of esophageal diverticula]. PMID- 4208763 TI - Isolation of Theileria mutans from cattle in Essex. PMID- 4208764 TI - Lassa fever and Marburg virus disease. PMID- 4208766 TI - [Example for testing cleaning agents and disinfectants as to probable usefulness (author's transl)]. PMID- 4208765 TI - [On the standardization of surface disinfection-tests (author's transl)]. PMID- 4208767 TI - [Subcapsular liver hematoma in the newborn infant and epilepsy in the mother]. PMID- 4208768 TI - Effect of barometric pressure change on the ear following stapedectomy. PMID- 4208770 TI - Heat stability of the precipitin reactants in normal chicken sera. PMID- 4208769 TI - Genetic control of urea resistant esterase of liver extracts in chicken. PMID- 4208771 TI - Studies on the mechanism of action of nalidixic acid. AB - With three independent techniques (absorption spectrophotometry, measurement of the deoxyribonucleic acid [DNA] melting temperature, and equilibrium dialysis), no evidence has been found for the binding of nalidixic acid to purified DNA. Also, no evidence has been found to support the hypothesis that nalidixic acid is permanently modified to a new, active compound by the bacterial cell. By using an in vitro DNA replication system developed by Bonhoeffer and colleagues, soluble extracts from nalidixic acid-sensitive cells have been shown to confer nalidixic acid sensitivity on the DNA synthesis of lysates from nalidixic acid-resistant cells. The activity in the extracts is only present in sensitive cells and is nondialyzable and heat sensitive. Finally, two known nalidixic acid-resistant mutants of Escherichia coli, mapping at nal A and nal B, respectively, have been tested to determine whether either of them is a transport mutant. It has been shown that nal B(r) is a transport mutant whereas nal A(r) is not. PMID- 4208772 TI - Protein-bound sulfhydryl groups and thiolesters in mitochondria and submitochondrial particles and their relationships to oxidative phosphorylation. PMID- 4208773 TI - Interaction of spinach leaf adenosine diphosphate glucose alpha-1,4-glucan alpha 4-glucosyl transferase and alpha-1,4-glucan, alpha-1,4-glucan-6-glycosyl transferase in synthesis of branched alpha-glucan. PMID- 4208774 TI - Bacillus licheniformis 749-C plasma membrane penicillinase, a hydrophobic polar protein. PMID- 4208775 TI - Studies on spinach leaf ribulosebisphosphate carboxylase. Carboxylase and oxygenase reaction examined by immunochemical methods. PMID- 4208776 TI - Purification and properties of T2 bacteriophage-induced thymidylate synthetase. PMID- 4208777 TI - Purification of rat urinary kallikreins and their specific antibody. PMID- 4208778 TI - Topography of ribosomal proteins of the Escherichia coli 30S subunit as studied with the reversible cross-linking reagent methyl 4-mercaptobutyrimidate. PMID- 4208779 TI - Platelet satellitism. PMID- 4208780 TI - Responsiveness of human granulocytic leukemic cells to colony-stimulating factor. PMID- 4208781 TI - [Activity of some enzymes of glycogen metabolism in the wall of lymphatic and blood vessels]. PMID- 4208782 TI - The synaptinemal complex in homologous and nonhomologous pairing of chromosomes. PMID- 4208783 TI - One the nature of chromosome-sized DNA molecules. PMID- 4208784 TI - The units of DNA replication in Drosophila melanogaster chromosomes. PMID- 4208785 TI - Organization and transcription of DNA in chromosomes and mitochondria of Drosophila. PMID- 4208787 TI - Bulk isolation of metaphase chromosomes from an in vitro cell line of Drosophila melanogaster. PMID- 4208786 TI - Characterization of the rapidly renaturing sequences in the main CsCl density bands of Drosophila, mouse, and human DNA. PMID- 4208788 TI - Repetitive sequences in isolated Thomas circles from Drosophila melanogaster. PMID- 4208789 TI - Repetitive DNA in polytene chromosomes of Drosophila melanogaster. PMID- 4208790 TI - Studies on the transfer RNA genes of Drosophila. PMID- 4208791 TI - Unequal mitotic sister chromatid exchange and disproportionate replication as mechanisms regulating ribosomal RNA gene redundancy. PMID- 4208792 TI - An examination of the one cistron: one chromomere concept. PMID- 4208793 TI - Analysis of a whole chromosome in Drosophila. PMID- 4208794 TI - The one band-one gene hypothesis: evidence from a cytogenetic analysis of mutant and nonmutant rearrangement breadpoints in Drosophila melanogaster. PMID- 4208795 TI - Organization of chromomeres. PMID- 4208796 TI - Chromosome structure in ciliated protozoans. PMID- 4208797 TI - Temporal control of puffing activity in polytene chromosomes. PMID- 4208798 TI - Transcription and chromatin structure. PMID- 4208799 TI - Ultrastructure of active eukaryotic genomes. PMID- 4208800 TI - [The hepatitis B antigen]. PMID- 4208801 TI - Experimental glaucoma in the rhesus monkey. PMID- 4208803 TI - Some enzymic properties of human lens esterase I. PMID- 4208804 TI - Intraocular pressure following long posterior ciliary canal cautery in primates. PMID- 4208802 TI - Lenticular and fundus changes induced by the intraocular infusion of sodium aspartate. PMID- 4208805 TI - The nature of chorioretinal lesions produced by the gallium arsenide laser. PMID- 4208806 TI - Transient lack of thyrotropin (TSH) response to thyrotropin-releasing hormone (TRH) in treated hyperthyroid patients with normal or low serum thyroxine (T4) and triiodothyronine (T3). PMID- 4208807 TI - Serum growth hormone and prolactin response to thyrotropin-releasing hormone in patients with acromegaly before and after surgery. PMID- 4208808 TI - Parathyroid function in patients with hyper- or hypothyroidism. PMID- 4208809 TI - Recovery of function: a review of studies pertaining to the serial lesion procedure and brain damage in infancy. PMID- 4208810 TI - Letter: Effect of Rev 1 vaccination. PMID- 4208811 TI - Assessment of bowel viability using 99Mtechnetium-tagged albumin microspheres. PMID- 4208812 TI - Experimental evaluation of the "gastric barrier" in CSF shunt infections. PMID- 4208813 TI - The study of bile salt kinetics in the experimental animal using a new technique. PMID- 4208814 TI - [Spinal autonomic paroxysms]. PMID- 4208815 TI - Histopathology of the myocardium in 50 apparently healthy cats. PMID- 4208816 TI - Spontaneous diabetes in monkeys. PMID- 4208817 TI - Clinical assessment of reproductive function in female rhesus monkeys: individual physical examination. PMID- 4208818 TI - [Participation of microorganisms in the transformation of propylene glycol, a component of waste waters]. PMID- 4208819 TI - [Effect of the toxic metabolites of Bacillus subtilis-mesentericus on tumorous and normal cells in tissue culture]. PMID- 4208820 TI - [Newly discovered sugars in the specific polysaccharides of bacteria]. PMID- 4208821 TI - [Oxidation of hydrocarbons by some bacteria of the genera Pseudomonas and Bacillus]. PMID- 4208822 TI - [Effect of blue-green algal hydrolysate on Candida tropicalis reproduction on a mineral medium with n-alkanes]. PMID- 4208823 TI - [Acid formation by fungi of the genus Aspergillus Mich. growing on media with petroleum hydrocarbons]. PMID- 4208824 TI - [Formation of microcide-resistant bacterial forms]. PMID- 4208825 TI - [Sensitivity of Bac. megaterium to the action of the blood serum of cancer patients]. PMID- 4208826 TI - [Key for the determination of saprophytic fluorescing bacteria of the genus Pseudomonas]. PMID- 4208827 TI - [Passive euthanasia--everyday problem for long term care physicians]. PMID- 4208829 TI - Editorial: Drugs in asthma. PMID- 4208828 TI - Lethal trait A 46 in cattle. Immunological investigations. PMID- 4208830 TI - The changing role of occupational therapy. PMID- 4208831 TI - Characterization of salivary proteins in patients with Sjogren's syndrome. PMID- 4208832 TI - Biologic effects of dental materials. 3. Toxicity and antimicrobial effect of endodontic antiseptics in vitro. PMID- 4208833 TI - Micromelic type of spondylo-meta-epiphyseal dysplasia. PMID- 4208834 TI - IgG subclasses: relationship to clinical aspects of multiple myeloma and frequency distribution among M-components. PMID- 4208835 TI - The effect of products D and E on the thrombin induced conversion of fibrinogen to fibrin. PMID- 4208836 TI - Red-cell carbonic anhydrase isoenyzmes in megaloblastic anaemia. PMID- 4208837 TI - Fine structure of rat incisor ameloblasts in transition between enamel secretion and maturation stages. PMID- 4208839 TI - F116, D3 and G101: temperate bacteriophages of Pseudomonas aeruginosa. PMID- 4208838 TI - Characteristics of a nucleoproteinaceous subviral entity resulting from partial degradation of southern bean mosaic virus. PMID- 4208840 TI - effects of aldehyde fixation and of preganglionic denervation on acetylcholinesterase and butyrocholinesterase of cat autonomic ganglia. PMID- 4208841 TI - Squirrel monkey platform runway test. A preliminary report. PMID- 4208842 TI - Hydrogen-tritium exchange in polypeptides. Models of alpha-helical and beta conformations. PMID- 4208843 TI - The switch point in mu heavy chains of human IgM immunoglobulins. PMID- 4208844 TI - Isolation and properties of the principal liver protein conjugate of a hepatic carcinogen. PMID- 4208846 TI - Characterization of an additional protein in pancreatic juice of men with chronic calcifying pancreatitis. Identification to lactoferrin. PMID- 4208845 TI - Kinetics of interaction of cyanate ion with cobalt bovine carbonic anhydrase. PMID- 4208848 TI - Anterior pharyngeal pouch. PMID- 4208847 TI - Can Aspergillus flavus cause maduromycetoma? PMID- 4208849 TI - Three unusual foreign bodies. PMID- 4208850 TI - Microtubules and movement in the archigregarine, Selenidium fallax. PMID- 4208851 TI - The purification and properties of a ribonuclease of the roe of the scallop Chlamys opercularis. PMID- 4208852 TI - Protein synthesis in a cell-free preparation from rumen Protozoa. PMID- 4208853 TI - Angiokeratoma corporis diffusum (Fabry's diseases). PMID- 4208854 TI - Human pancreatic proteolytic enzymes and protein inhibitors. Isolation and molecular properties. PMID- 4208855 TI - Selection for reduced crossing over in Drosophila melanogaster. AB - Selection was practiced for reducing crossing over between the third chromosome genes Sb and H(2) of Drosophila melanogaster; the method employed was to select the repulsion double heterozygotes Sb+/+H(2) every generation. Two replicate selection lines were maintained. After 24 generations of selection, Line 1 showed no significant difference from the control, although the regression of recombination value on generation was significant. In generation 20, Line 2 had a significantly lower recombination value than the control, as well as having a highly significant regression coefficient. No chromosome rearrangements were involved in the response. It was concluded that there was substantial genic variability in the frequency of crossing over between Sb and H(2) in the base population. PMID- 4208856 TI - On recombination-defective meiotic mutants in Drosophila melanogaster. AB - The genetic effects of four recombination-defective meiotic mutants in D. melanogaster on recombination, segregation and the relationship between the two have been examined. The results suggest the following. (1) The anomalous meiotic segregation observed in females carrying recombination-defective meiotic mutants is a normal consequence of the reduction in exchange; each recombination defective mutant can, therefore, be defined by a single lesion in the control of recombination. (2) Of the operations used to date to characterize this lesion, the most informative is whether the decrease in recombination is uniform along the chromosome arm or nonuniform; in particular, if the formation of recombinants is visualized as a two-step process consisting of the establishment of possible exchange points (exchange preconditions) followed by exchange itself, then mutants that uniformly decrease crossing over involve defects in the second step while mutants that result in a nonuniform decrease involve defects in the establishment of exchange preconditions. (3) Of the fourteen loci identified by recombination-defective meiotic mutants, only one (with two alleles) is involved in exchange itself; the others all reduce recombination most drastically in distal regions, suggesting that the establishment of exchange preconditions involves polar processes. (4) A very general description of the polar establishment of exchange preconditions is presented; this description has the property that if a precondition meiotic mutant affects interference, the coefficient of coincidence will be increased in proportion to the decrease in recombination which is what is observed for all recombination-defective meiotic mutants studied to date. PMID- 4208857 TI - Genetic dissection of segregation distortion. I. Suicide combinations of SD genes. AB - Two major loci in the Tft-cn region of an SD chromosome have been separated by recombination and identified. The allele at the left-hand locus on an SD chromosome is called Sd; the allele at the right-hand locus is called Rsp. Both Sd and Rsp are necessary to bring about a distortion of the segregation ratio in heterozygous SD males, although the particular degree of distortion exhibited by an SD chromosome is influenced by the constellation of polygenic modifiers of SD in the genome. The coupling phase of the alleles, Sd Rsp/Sd(+)Rsp(+), produces about 89-90% of Sd Resp-bearing progeny. The repulsion phase, Sd Rsp(+)/Sd(+)Rsp, produces 10-20% of Sd Rsp(+)-bearing progeny. No coupling-repulsion effects between Sd and Rsp are apparent. PMID- 4208859 TI - A cold-sensitive zygotic lethal causing high frequencies of nondisjunction during meiosis I in Drosophila melanogaster females. AB - The X-linked, cold-sensitive zygotic lethal, l(1)TW-6(cs), both in homozygous and heterozygous females, induces nondisjunction of all four chromosomes at Meiosis I at both 25 degrees and 17 degrees . Nondisjunction frequencies approaching 0.5 for the X and fourth chromosomes have been observed at 16 degrees -18 degrees . The disjunction of the X chromosomes in males is not affected. The mutant causes mitotic irregularities in zygotes at both 25 degrees and 17 degrees . Mortality of all zygotes produced by the crosses 6(cs)/6(cs)x6(cs)/B(s)Y and FM7/6(cs)x6(cs)/B(s)Y is respectively 86% and 67-74% at 25 degrees and 99.8-99.9% and 94% at 17 degrees . The mortality of 6(cs) hemizygotes derived from females carrying no doses of 6(cs) (C(1)DX,y f/yx6(cs)/B(s)Y) is 45-55% at 25 degrees and 98% at 17 degrees . The length of the temperature-sensitive period for 6(cs) homo and hemizygotes is affected by the maternal dosage of 6(cs); the shortest TSP is for zero and the longest is for two maternal doses. Mortality takes place primarily during embryogenesis with some larval and little pupal mortality. Analysis of sectioned embryos indicates that the large array of different patterns of damage observed could have arisen from abnormal cleavage divisions and the incomplete population of the blastoderm with nuclei. PMID- 4208860 TI - The effects of r- and K-selection on components of variance for two quantitative traits. AB - The genetic and environmental components of variance for two quantitative characters were measured in the descendants of Drosophila melanogaster populations which had been grown for several generations at densities of 100, 200, 300, and 400 eggs per vial. Populations subject to intermediate densities had a greater proportion of phenotypic variance available for selection than populations from either extreme. Selection on either character would be least effective under pure r-selection, a frequent attribute of selection programs. PMID- 4208858 TI - The developmental genetics of the temperature sensitive lethal allele of the suppressor of forked, 1(1)su(f)ts67g, in Drosophila melanogaster. AB - A temperature-sensitive lethal allele of suppressor of forked, l(1)su(f)(ts67g) (ts67), has been discovered and characterized as follows: Flies which are hemizygous for ts67 live at 18 degrees and 25 degrees but die at 30 degrees primarily as larvae. The temperature-sensitive period for ts67 homozygotes or hemizygotes begins in second instar and ends at pupation. ts67 is lethal at 30 degrees when heterozygous with suppressor of forked (su(f)), a deficiency for suppressor of forked (su(f)(-)), and a non-conditional lethal allele of suppressor of forked (3DES). It is viable at 30 degrees when heterozygous with the wild-type allele of suppressor of forked. At 25 degrees but not at 18 degrees forked bristles are suppressed in flies of the following genotypes: f(s)ts67/Y, f(s)ts67/f(s)ts67, f(s)ts67/f(s)su(f), f(u)ts67/f(s)3DES, f(u)ts67/f(s)su(f)(-), f(u)ts67/f(s)su(f). There is some suppression of forked bristles at 25 degrees in the heterozygote, f(s)ts67/f(s)+(su(f)). The forked bristle phenotype is not suppressed at either temperature in flies of the genotypes f(u)ts67/Y, f(u)ts67/f(u)ts67/ (f(s) and f(u) indicating suppressible and unsuppressible alleles of forked). The temperature-sensitive period for suppression of forked bristles begins at pupation and extends through the period of bristle synthesis. The deficiency phenotype (bristles reduced in size or absent, wing wrinkled or blistered, eyes rough) typical of flies of the genotype f(s)su(f)/f(s)su(f)(-) at 18 degrees and 25 degrees , is exhibited by flies of the genotypes f(s)ts67/f(s)su(f)(-) at 25 degrees and f(u)ts67/f(s)su(f) at 29 degrees . An allele of lozenge (lz(1)) which can be suppressed by su(f) is suppressed at 25 degrees but not at 18 degrees in lz(1)ts67/Y males. ts67 homozygous females are fertile at 25 degrees but sterile at 30 degrees . The hypothesis is discussed that the su(f) locus codes for a ribosomal protein and that suppression and enhancement are affected by mutations at the locus by mutant ribosome-induced misreading. The possibility is presented that ts67 may be used to determine the translation time in development of any gene. PMID- 4208861 TI - The distribution of mucins in the nasopharynx of some primates. PMID- 4208863 TI - Proceedings: The pharyngeal hypophysis in the laboratory animal. PMID- 4208862 TI - Development of the secondary interstitial gland in the rabbit ovary. PMID- 4208864 TI - Proceedings: Immunoglobulin in pig salivary gland homogenates. PMID- 4208865 TI - Proceedings: Gene frequency variation in Kenya baboon populations. PMID- 4208866 TI - Hearing in the owl monkey (Aotus trivirgatus). I. Auditory sensitivity. PMID- 4208868 TI - Ovarian hormones and sexual behavior in Macaca Nemestrina. PMID- 4208867 TI - Thermal thresholds of the rhesus monkey (Macaca mulatta). PMID- 4208870 TI - Effect of fragmentation on interferon induction by double-stranded virus RNA. PMID- 4208869 TI - The effect of enzymes on structural and biological properties of Semliki forest virus. PMID- 4208871 TI - Tissue fixation with diimidoesters as an alternative to aldehydes. I. Comparison of cross-linking and ultrastructure obtained with dimethylsuberimidate and glutaraldehyde. PMID- 4208872 TI - Amodioquine induced oral pigmentation--a light and electron microscopic study. PMID- 4208873 TI - The effects of bacterial plaque extracts on organ cultures of fetal rat masticatory mucosa. I. Histochemistry. PMID- 4208874 TI - The effects of bacterial plaque extracts on organ cultures of fetal rat masticatory mucosa. II. Electron microscopy. PMID- 4208875 TI - The crypt surface of blade-vent implants in clinical failure: an electron microscopic study. PMID- 4208876 TI - [Late spondylo-epiphyseal dysplasia. Apropos of 3 new cases]. PMID- 4208877 TI - [Bronchographies using tantalum aerosol. Toxicological study of the contrast medium]. PMID- 4208878 TI - [Simulation in radiotherapy]. PMID- 4208879 TI - Translation of Pseudomonas aeruginosa bacteriophage PP7 RNA by a cell-free amino acid incorporating system from Escherichia coli. AB - We have compared the activities of the RNA genomes of Pseudomonas aeruginosa phage PP7 and coliphages Qbeta and f2 in a cell-free amino acid incorporating system derived from Escherichia coli. The rate of incorporation of [(14)C]leucine in the PP7 RNA-directed system is greater than in the systems directed by either Qbeta or f2 RNA. The response to changes in phage RNA concentrations is similar in all the systems, reaching a saturation level at 0.75 to 1.0 mg of RNA per ml of reaction mixture. Analysis of complete reaction mixtures of the PP7 RNA and of the Qbeta RNA systems by sucrose gradient centrifugation shows generally similar patterns for both RNAs. The principal differences are that in the PP7 system a slightly higher percentage of RNA forms ribosome complexes and that the polysomes are somewhat smaller. PP7 RNA is also degraded more extensively during the reaction than is Qbeta RNA. Analysis of the products of the reactions by acrylamide gel electrophoresis shows that PP7 coat protein is the only identifiable product of the PP7 RNA-directed system, suggesting that only the coat protein cistron is translated by E. coli ribosomes. PMID- 4208881 TI - Strains of Bacillus subtilis synthesizing elevated levels of isoleucine-valine biosynthetic enzymes. PMID- 4208880 TI - Ribosomal protein neighborhoods. 3. Cooperativity of assembly. PMID- 4208882 TI - [Synthesis of 5-hydroxytryptophane using microbiological hydroxylation of L tryptophane]. PMID- 4208883 TI - The demonstration of antibodies to Sarcocystis fusiformis antigen in sera of Isospora hominis carriers, using the indirect fluorescence technique. PMID- 4208884 TI - Biliary excretion of some penicillins, quaternary ammonium compounds and tertiary amines, including aspects on mechanisms for their excretion. PMID- 4208886 TI - The indirect immunoenzyme test for the detection of antibodies against North American Borreliae. I. Technic and results with sera of vervet monkeys (Cercopithecus aethiops). PMID- 4208885 TI - Differentiation of the contractile effects of prostaglandin E2 and the C-terminal octapeptide of cholecystokinin in isolated guinea-pig gallbladder. PMID- 4208887 TI - Efficacy of the Candida precipitin test. Verification with a protoplast antigen preparation. PMID- 4208888 TI - Rapid detection of bacteremia by a radiometric system. A clinical evaluation. PMID- 4208889 TI - Parenteral nutrition in seriously ill neonates. Search for the ideal mixture. PMID- 4208890 TI - Serum proteins in hepatosis of pregnancy and pre-eclampsia. PMID- 4208891 TI - Pigmenturia from conga drumming. Hemoglobinuria and myoglobinuria. PMID- 4208892 TI - Care of the aged: an English lesson? PMID- 4208893 TI - Editorial: How clinically useful is T and B cell quantitation? PMID- 4208894 TI - Autonomic drugs in ophthalmology: some problems and promises. I. Directly and indirectly acting parasympathomimetic drugs. PMID- 4208895 TI - Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. AB - A new cephalosporin with a highly reactive beta-lactam ring was found to give an immediate color change in the presence of beta-lactamases from many bacteria, including staphylococci, Bacillus species, Enterobacteriaceae, and Pseudomonas. The reaction is confined to organisms producing beta-lactamases, but it is sufficiently sensitive to indicate the presence of this enzyme is small amounts in strains previously considered not to produce it. The compound has an unusual ultraviolet spectrum, and the color change can be followed quantitatively by measuring changes in absorption which occur in the 380- to 500-nm region, where cephalosporins normally have no absorption. The development of color is thought to be a consequence of the beta-lactam ring being unusually highly conjugated with the 3-substituent. Although in the bacteria only beta-lactamases produce this color change, it was found that serum and tissues from experimental animals also rapidly produced the colored breakdown product, which was then excreted in the urine. The mechanism of the mammalian breakdown was considered to be different from that found in bacteria. PMID- 4208896 TI - Evaluation of a new cephalosporin antibiotic, cephapirin. AB - Cephapirin sodium, a parenterally administered derivative of cephalosporanic acid, was tested in vitro against 150 stock cultures of Enterobacteriaceae and 30 stock cultures each of Pseudomonas aeruginosa and Staphylococcus aureus. Both broth- and agar-dilution techniques were employed with two sizes of inocula of organisms. At a concentration of 7.5 mug or less/ml, cephapirin inhibited and killed 100% of strains of Escherichia coli and Proteus mirabilis and more than 80% of Klebsiella species when tested against an inoculum of 10(5) bacterial cells/ml. However, even at 100 mug/ml, only a few isolates of other Enterobacteriaceae and Pseudomonas were inhibited. A 100-fold increase in the inoculum resulted in decreased susceptibility of organisms. All penicillin susceptible as well as penicillin-resistant S. aureus isolates were inhibited and killed by 5 mug or less of cephapirin/ml when tested with an inoculum of either 10(4) or 10(6) organisms/ml. The drug also was studied in various doses in the treatment of 77 patients with diverse infections. Cephapirin was effective in the treatment of 27 of 32 patients with pulmonary infection, as well as in 6 of 7 patients with staphylococcal or streptococcal soft tissue infection. Of 25 patients with urinary-tract infections, 19 developed a negative culture during therapy. A single 4-g intramuscular dose of cephapirin was effective in only 2 of 11 patients with gonococcal urethritis or endocervicitis. Two patients with gonococcal urethritis treated with multiple injections were cured. The drug was well tolerated except for pain at the site of injection in 14 patients and phlebitis in 4 patients. No abnormalities in renal or hepatic function could be attributed to cephapirin. In addition, no abnormalities were found in the renal tubules of rabbits challenged with 500 mg of cephapirin/kg. If further studies document that cephapirin is well tolerated by the parenteral route, it may have advantages over cephalothin or cephaloridine. PMID- 4208897 TI - Effect of exogenous penicillin on penicillin biosynthesis. AB - The addition of phenoxymethylpenicillin (10 mg/ml) at any time during the penicillin fermentation inhibited further accumulation of the antibiotic in broth but had no effect on growth. Benzylpenicillin, 6-aminopenicillanic acid (6-APA), and some semisynthetic penicillins also showed this effect, but penicillin N, penicilloic acid, cephalosporin C, and 7-aminocephalosporanic acid did not limit penicillin accretion. Incorporation of radioactive precursors (cysteine, valine, and sodium phenoxyacetate) into penicillin in the presence of inhibitory concentrations of the antibiotic indicated that penicillin synthesis continued despite the lack of accretion of the antibiotic in broth. The rates of penicillin synthesis in a 48-hr and a 136-hr culture were compared by short-term exposure to Na(2) (35)SO(4), and no significant difference in the biosynthetic rate was observed. Exogenous penicillin in the range of 1 to 15 mg/ml of culture broth had no effect on utilization of acetate or glucose by Penicillium chrysogenum. The antibiotic-synthesizing capacity of the organism was not irreversibly inhibited by exogenous penicillin. The degradation of penicillin during the fermentation was also studied. Penicillin V was stable in broth filtrate. Catabolic enzymes such as penicillinase and penicillin-acylase were not demonstrated in whole broth, nor was the accumulation of 6-APA, penicilloic acid, or other degradation products detected. An examination of the intracellular penicillin concentration and the amount of penicillin associated with the mycelium revealed that cells contained significantly more penicillin late in the fermentation than earlier in the cycle. This cell-associated antibiotic may be a regulatory factor in further penicillin synthesis. PMID- 4208898 TI - Factors influencing the microbiological assay of tobramycin. AB - Tobramycin belongs to the aminoglycoside class of antibiotics. Assay procedures were investigated to determine the most suitable methods for the assay of tobramycin in blood, urine, and pharmaceutical preparations. The agar-plate assay was the method of choice for determinations in urine and serum. The turbidimetric assay was selected for the assay of pharmaceutical preparations. An extraction technique is described that minimizes problems encountered in the estimation of tobramycin in urine. Sample diluents, pH, and molarity were important and were variable depending on assay methods. Evidence is presented to show binding of tobramycin to alpha-cellulose susceptibility discs. Iron and sodium ions demonstrated potential inhibition of tobramycin in all assay methods tested. PMID- 4208899 TI - Effect of chemotherapeutic agents upon microorganisms isolated from cancer patients. AB - Attempting to explain the predominance of Pseudomonas in leukemic patients, five of the most common gram-negative organisms isolated from sites of infection in cancer patients were exposed to several of the chemotherapeutic agents used in the treatment of this disease (methotrexate, cytosine arabinoside, cyclophosphamide, and 6-mercaptopurine). At concentrations of 125 mug/ml or higher, methotrexate inhibited all organisms except Pseudomonas. Cytosine arabinoside inhibited Escherichia and Klebsiella but appeared to stimulate the growth of Pseudomonas slightly at the higher concentrations. Thus, significant differences existed in individual susceptibilities to these agents. Clinical isolates were more resistant than the corresponding laboratory strains not previously exposed to these compounds. The resistance of Escherichia coli to cyclophosphamide was decreased 26% when it was grown in mixed culture with Pseudomonas. Only Pseudomonas was resistant to all of these compounds whether in pure or mixed culture. These observations may help to explain, in part, the predominant role that Pseudomonas plays as an infectious agent in leukemic patients. PMID- 4208900 TI - Scanning electron microscopy of the H37Ra strain of Mycobacterium tuberculosis exposed to isoniazid. AB - The morphology of cells of the H37Ra strain of Mycobacterium tuberculosis exposed to 0.5 mug of isonicotinic acid hydrazide (isoniazid) per ml was examined by scanning electron microscopy (SEM). Cells that were exposed to isoniazid for 3 h showed no detectable change, whereas cells exposed to the drug for 24 h exhibited diverse morphological features. From our examination of these SEM pictures, we have reconstructed the probable sequence of morphological changes to be as follows: (i) the wrinkling of the cell surface was ascribed as the earliest observable change, (ii) the cell surface then became very rough and ragged, (iii) eventually the cytoplasmic material was extruded from the cell, (iv) this event produced a collapsed cell, (v) the cells began to fragment, (vi) the fragmented cells then coalesced to form an amorphous mass of cell debris. PMID- 4208901 TI - Bactericidal action of an antibiotic produced by Myxococcus xanthus. AB - Myxococcus xanthus produced an antibiotic during the end of its exponential growth phase which was capable of inhibiting growth of several gram-positive and gram-negative bacteria. The antibiotic was bactericidal to growing cultures only; chloramphenicol inhibited the bactericidal action of the antibiotic. Upon addition of the antibiotic to Escherichia coli B, deoxyribonucleic acid and ribonucleic acid as well as turbidity of the culture continued to increase even after the viable count decreased; the culture lysed about 60 min after addition of sufficient concentrations of the antibiotic. Spheroplasts could be prepared if the antibiotic was added to a culture growing in the presence of high concentrations of sucrose and MgSO(4). Mutants of M. xanthus FB which are incapable of fruiting body formation or glycerol-induced myxospore formation also produced the antibiotic. A mutant of E. coli resistant to the purified antibiotic was isolated in order to study the role of the antibiotic in the predatory behavior of myxococci. PMID- 4208902 TI - Streptococcal pharyngitis therapy: comparison of clindamycin palmitate and potassium phenoxymethyl penicillin. AB - Clindamycin palmitate and potassium phenoxymethyl penicillin were evaluated in 103 children with upper respiratory illnesses and pharyngeal group A streptococci, from November 1970 to July 1971. The children were assigned randomly by weight to one of the antibiotic regimens given orally for 10 days. Clindamycin palmitate and potassium phenoxymethyl penicillin dosages were 75 and 125 mg, respectively, in 5 ml tid for children weighing less than 25 kg, and 150 and 250 mg, respectively, in 10 ml bid for children weighing 25 kg or more. Recurrences of the original streptococcal group A, M, and T types within 3 weeks after the end of treatment were classified as failures. The failure rates were: clindamycin palmitate, 10% (5 of 52), and potassium phenoxymethyl penicillin, 18% (9 of 51). Possible drug-related rashes were observed in 8 of 52 clindamycin palmitate-treated patients. The geometric mean minimal inhibitory concentrations of clindamycin and penicillin against 103 isolates of group A streptococci were 0.033 and 0.007 mug/ml, respectively. The serum concentrations about 70 min after ingesting 150 mg of clindamycin palmitate averaged 3.8 mug/ml and after 250 mg of potassium phenoxymethyl penicillin averaged 0.9 mug/ml. Clindamycin palmitate was as effective as potassium phenoxymethyl penicillin in eradicating group A streptococci from the pharynx in tid and bid regimens. Nevertheless, because of its rash-producing tendency in some patients and higher cost, clindamycin palmitate should not be preferred to penicillin for treatment of streptococcal sore throat in the non-penicillin-allergic patient. PMID- 4208903 TI - [Composition of nonconjugated pteridines in phototrophic bacteria]. PMID- 4208904 TI - Letter: Chronic brucellosis. PMID- 4208906 TI - Variation in the occurrence of extracellular diffusible antigens in temperature induced variants of Erwinia herbicola Y46, and observations of their relationships with Erwinia amylovora. PMID- 4208905 TI - Letter: Treatment of meningococcal carriers. PMID- 4208907 TI - The in vitro degradation of the herbicide bromoxynil. PMID- 4208908 TI - Endotracheally administered gentamicin for the prevention of infections of the respiratory tract in patients with tracheostomy: a double-blind study. PMID- 4208909 TI - Australia hepatitis-associated antigen in cirrhosis of the liver at Aurangabad. PMID- 4208910 TI - Haemagglutination by Chikungunya virus--pH range and erythrocytes of different animals. PMID- 4208911 TI - Nematodes in rhesus monkeys. PMID- 4208912 TI - Kinetics of formation and dissociation of manganese-bovine carbonic anhydrase B. PMID- 4208914 TI - The relationship between PF-DIL and activated human Hageman factor. PMID- 4208915 TI - IgM-forming cells as the immediate precursor of IgA-producing cells during ontogeny of the immunoglobulin-producing system of the chicken. PMID- 4208913 TI - Hypothalamic regulatory hormones: a review. PMID- 4208916 TI - Dissociation and recombination of the subunits of the cholera enterotoxin (choleragen). PMID- 4208917 TI - Chain interactions and idiotypic specificities of homogeneous rabbit anti-lactose antibodies. PMID- 4208918 TI - Effector mechanisms of cell-mediated immunity to xenogeneic cell antigens. PMID- 4208919 TI - Interaction of isoantibody and cytotoxic lymphocytes with allogeneic tumor cells. PMID- 4208920 TI - Modification of NZB-NZW F1 autoimmune disease by development of tolerance to DNA. PMID- 4208921 TI - Crossed immunoelectrophoresis and electroimmunoassay of IgG. PMID- 4208922 TI - The occurrence of shared idiotypic specificity among the goat antibodies that distinguish human hemoglobin S from A. PMID- 4208923 TI - Serum immunoglobulin E levels in patients with neoplastic disease. PMID- 4208924 TI - Studies on human secretory immunoglobulin A. VI. Cyanogen bromide cleavage. PMID- 4208925 TI - Prevention of myeloma growth in BALB-c mice by injection of anti-immunoglobulin antisera. PMID- 4208926 TI - Interaction of C-reactive protein complexes with the complement system. II. Consumption of guinea pig complement by CRP complexes: requirement for human C1q. PMID- 4208927 TI - The diagnosis of ruptured fetal membranes by measurement of the diamine oxidase (DAO) activity in vaginal fluid. PMID- 4208928 TI - [Report of the month: blood and blood substitution]. PMID- 4208929 TI - [Denitrifying bacteria isolated from sulfide ore deposits]. PMID- 4208930 TI - [Efficiency of free energy utilization by hydrogen-oxidizing bacteria]. PMID- 4208931 TI - [Evaluation of the physiological state of hydrogen bacteria cells by spectrofluorometry]. PMID- 4208932 TI - [Symbiotic oxidation of carbon monoxide by bacteria]. PMID- 4208933 TI - [Calculation of the energy substrate demand by hydrogen bacteria]. PMID- 4208934 TI - [Hydrogen bacteria bacteriophages and the phenomenon of lysogeny in these cultures]. PMID- 4208935 TI - [Formation of different forms of hydrogenases in Rhodospirillum rubrum depending on the growing conditions]. PMID- 4208936 TI - [Localization of the nucleases in the cells of Bacillus subtilis]. PMID- 4208937 TI - [Growth conditions and the formation of antibiotics by a mutant of Bacillus polymyxa var. Ross 26]. PMID- 4208939 TI - Letter: Alcoholic cirrhosis in baboons. PMID- 4208940 TI - [Traumatic epilepsy]. PMID- 4208942 TI - [Interpretation of functional and structural correlations in post-traumatic epilepsy]. PMID- 4208941 TI - [Experimental post-traumatic epileptogenic foci activated with penicillin]. PMID- 4208938 TI - Comparative studies of alpha-lactalbumin and lysozyme: Echidna lysozyme. PMID- 4208943 TI - [Post-traumatic epilepsy in a population of a town with 14,000 inhabitants]. PMID- 4208944 TI - [Post-traumatic epilepsy in the population of a large industrial city]. PMID- 4208945 TI - [Some aspects of post-traumatic epilepsy]. PMID- 4208946 TI - [Analysis of cases of post-traumatic epilepsy in the records of the Epileptic Outpatient Clinic at the Provincial Mental Health Center at Bialystok]. PMID- 4208947 TI - [Post-traumatic epilepsy in the records of the Neurologic Clinic of the Institute of Psychoneurology]. PMID- 4208948 TI - [Epilepsy in children with a history of head injuries in the records of the Department of Neurology of the Medical Academy at Bialystek]. PMID- 4208949 TI - [Diagnostic difficulties in post-traumatic epilepsy in children]. PMID- 4208950 TI - [Psycho-organic chronic sequelae of post-traumatic epilepsy in children]. PMID- 4208951 TI - [Early epileptic seizures following head injuries in children]. PMID- 4208952 TI - [Neurotic reactions in children with post-traumatic epilepsy]. PMID- 4208953 TI - [Electroencephalographic studies in post-traumatic epilepsy]. PMID- 4208954 TI - [Clinical and social aspects of post-traumatic epilepsy in women]. PMID- 4208955 TI - [Prevention and treatment of post-traumatic epilepsy]. PMID- 4208956 TI - [Results of surgical treatment of post-traumatic epilepsy]. PMID- 4208957 TI - [Surgical treatment of post-traumatic epilepsy and operative results]. PMID- 4208958 TI - [Some intellectual functions in school children on long-term therapy for epilepsy]. PMID- 4208959 TI - Neutralizing and precipitating antibodies against infectious bronchitis virus in chickens. PMID- 4208961 TI - Normal physiological patterns and physiological-behavioral correlations in unrestrained monkey infants. PMID- 4208960 TI - A study of the histologic reaction of submerged root segments. PMID- 4208962 TI - Effects of dihydrotestosterone on sexual behavior of castrated male rhesus monkeys. PMID- 4208963 TI - Schedule-induced drinking following omission of reinforcement in the rhesus monkey. PMID- 4208964 TI - Irradiation in the local control of malignant lymphoreticular tumors (non Hodgkin's malignant lymphoma). PMID- 4208965 TI - Correlation of physical characteristics of 4 MV X-ray beams with skin reactions of patients undergoing radiation therapy. PMID- 4208966 TI - [Results of gel precipitation reactions in the diagnosis of Botkin's diseases]. PMID- 4208967 TI - [Detection of Australia antigen in patients with viral hepatitis and other diseases]. PMID- 4208968 TI - Mechanisms of renal excretion of urate in the rat. PMID- 4208969 TI - Tuberculous cervical lymphadenitis. PMID- 4208970 TI - Functional and histological findings in acoustic tumor. PMID- 4208971 TI - Cardiolipin specific phospholipase D activity in Escherichia coli extracts. PMID- 4208972 TI - Methionine transfer RNAs from the blue-green alga Anacystis nidulans. PMID- 4208973 TI - Peroperative evaluation of the viability of ischaemic colon in primates. PMID- 4208975 TI - Proceedings: Comparison of central venous pressure with continuous blood volume measurement during haemorrhage and infusion. PMID- 4208974 TI - Proceedings: The intracranial volume-pressure response during experimental brain compression in primates. PMID- 4208977 TI - [Sensitivity of liquid Banic's culture medium as compared with the Lowenstein Jensen-Holm's and the liquid Sula's culture medium]. PMID- 4208978 TI - Editorial: Budget cuts are not the answer. PMID- 4208979 TI - Classification of hypothyroidism in evaluating patients after radioiodine therapy by serum cholesterol, T3-uptake. Total T4, FT4-index, total T3, basal TSH and TRH test. PMID- 4208980 TI - Intramitochondrial bodies in the B-cells of rat's pancreas treated by glybenclamide. PMID- 4208981 TI - Basement membrane abnormalities in melanotic tumor formation of Drosophila. PMID- 4208982 TI - Antibodies to the insect moulting hormone beta-ecdysone. PMID- 4208983 TI - [The mechanism of action of carbidine]. PMID- 4208984 TI - [The relationship between the structure and T-anti-serotonin activity of several indole derivatives]. PMID- 4208985 TI - [An analysis of the mechanisms of the antianginal effect of nitroglycerin and morphine]. PMID- 4208987 TI - Australia antigen in the Solomon Islands. PMID- 4208986 TI - [The effect of nitroglycerin and sodium nitrite on evoked potentials of the cerebral cortex upon stimulation of the vagus and inferior cardiac nerves]. PMID- 4208988 TI - Fine structure and function of ocular tissues. The optic nerve. PMID- 4208989 TI - Review of progress and application in acoustis microscopy. PMID- 4208990 TI - Pulpal response of monkeys to a composite resin cement. PMID- 4208992 TI - [Studies on the anatomy and vascularization of the cerebellum of the baboon (Papio papio Desm.)]. PMID- 4208991 TI - The dorsal thalamus of the cat and comparison with monkey and man. PMID- 4208993 TI - Cholesterol metabolism in rhesus monkey, squirrel monkey, and baboon. AB - The metabolism of cholesterol was studied in baboons, rhesus monkeys, and squirrel monkeys while they were being fed either a low fat, low cholesterol (basal) diet or the basal diet supplemented with saturated fat and cholesterol (atherogenic diet). When the diet was changed from basal to atherogenic, the mean total serum cholesterol concentration increased from 70 to 180 mg/dl in the baboon, from 168 to 283 mg/dl in the squirrel monkey, and from 144 to 608 mg/dl in the rhesus monkey. In animals fed the atherogenic diet, the percentage of dietary cholesterol absorbed was greatest in the rhesus monkey and least in the baboon. The fraction of the total body pool of cholesterol that was derived from the diet was greatest in the squirrel monkey and least in the baboon. The turnover of the body pool of cholesterol was several times faster in the squirrel monkey than in the baboon or the rhesus monkey when either dict was fed. The mean total fecal excretion of endogenous cholesterol and bile acid increased in all species on transition to the atherogenic diet; however, the relative contributions of the neutral and acidic fractions to the increase in total excretion differed among species. The difference in percentage of dietary cholesterol absorbed may, in part, account for the large differences in serum cholesterol during the atherogenic diet period. Comparison with other published results indicates that of these species cholesterol metabolism in the baboon is most like that in the human. PMID- 4208994 TI - Products of linoleic hydroperoxide-decomposing enzyme of alfalfa seed. AB - Alfalfa seeds and seedlings contain an enzyme that catalyzes a reaction with the 13- and 9-hydroperoxides of linoleic acid to form 13-hydroxy-10-oxo-trans octadecenoic acid and 9-hydroxy-12-oxo-trans-10-octadecenoic acid, respectively. When commercial lipoxygenase is used to generate the hydroperoxides, the above acids appear in about 2:1 proportions, respectively. The products of the action of the enzyme on the hydroperoxides were stabilized for analysis by reduction with H(2) and LiAIH(4). Trimethylsilyl derivatives of reduced products were analyzed by combined gas-liquid chromatography-mass spectrometry. Specific deuterium labeling permitted definite location of the oxo functions. (18)O(2) labeling experiments showed that the oxygens of both the oxo and the hydroxyl functions were derived from the hydroperoxide. Retention of both oxygens suggests that the reaction proceeds through a cyclic epiperoxide followed by a ketohydroxy forming rearrangement. No products of hydroperoxide isomerase were found in reactions catalyzed by the crude enzyme from alfalfa seeds. PMID- 4208995 TI - Artifacts produced by acidic hydrolysis of lipids containing 3-hydroxyalkanoic acids. AB - After acidic hydrolysis of lipid A preparations from pseudomonads, products containing both hydroxy and nonhydroxy fatty acids were obtained. The major products were alkanoate esters of the hydroxy acids. Similar compounds were formed when a 3-hydroxy acid was heated with a nonhydroxy acid under the same conditions. PMID- 4208996 TI - Anti-C, anti-e and anti-Ce (rhi) as a cause of hemolytic disease of the newborn in a Thai family. PMID- 4208997 TI - The need for trained medical professionals. PMID- 4208998 TI - Drug rehabilitation in the combat zone. PMID- 4208999 TI - Categorization of seizure disorders in combat zone evacuees. PMID- 4209000 TI - Case for diagnosis. PMID- 4209001 TI - Home dialysis experience at Madigan Army Medical Center. PMID- 4209002 TI - Methoxyflurane nephrotoxicity: case report. PMID- 4209003 TI - Donnatal intoxication: case report. PMID- 4209004 TI - Delayed infection following tantalum cranioplasty: case report. PMID- 4209005 TI - Subarachnoid hemorrhage presenting as cardiac arrhythmia: case report. PMID- 4209006 TI - Editorial: oral fluid intake accuracy. PMID- 4209007 TI - Progressive ossification of the leptomeninges in atrophic encephalopathy. PMID- 4209009 TI - [Specificity of antibodies obtained during immunization of Rh-negative blood donors with erythrocytes of Rho (cDe) group]. PMID- 4209008 TI - [Study of the antigenic structure of burned human skin]. PMID- 4209010 TI - [Distribution of antigens of the Lewis and P system among Armenian population of Erevan]. PMID- 4209011 TI - [Rare case of sensitization to factors of Rh-Hr systems and hemotransfusion complications]. PMID- 4209012 TI - [Hemotransfusion shock in a patient with hemophilia A complicated by gangrene of the feet]. PMID- 4209013 TI - [Usefulness of a medium containing human albumin in the examination of the fermentative properties of Neisseria gonorrhoeae]. PMID- 4209014 TI - [Microscopic examinations of discharge smears and gonococcal culture in the diagnosis of gonorrhea]. PMID- 4209016 TI - [Carbonic anhydrase activity and blood zinc level in blood of x-irradiated rabbits]. PMID- 4209015 TI - [Changes in the secondary structure of bacterial DNA on exposure to small doses of ionizing radiation]. PMID- 4209017 TI - [Electron microscopy of the myocardium in human trypanosomiasis cruzi]. PMID- 4209018 TI - [Combined treatment of Chagas' disease with Bayer 2502 and corticoid (experimental and clinical study)]. PMID- 4209019 TI - [Comparative evaluation of the results of radiation therapy of laryngeal cancer]. PMID- 4209020 TI - [Comparative evaluation of immediate results of different types of radiotherapy of laryngeal cancer]. PMID- 4209021 TI - Ion exchange and affinity chromatography during the purification of human plasminogen on sepharose-L-lysine. PMID- 4209022 TI - Eight children with coexistent sickle cell anemia and plumbism. PMID- 4209023 TI - Did this boy have meningitis? PMID- 4209024 TI - Candida endocarditis and encephalitis in an infant. PMID- 4209025 TI - Candida endocarditis complicating glucose total intravenous nutrition. AB - A case of Candida albicans endocarditis is reported. The endocarditis occurred in a patient with a chronic illness who received intermittent glucose total intravenous nutrition for approximately 10 weeks. The patient developed severe aortic insufficiency with his valvular endocarditis and required emergency aortic valve replacement. Aggressive surgery and medical treatment appear to be the treatment of choice for these critically ill patients. PMID- 4209026 TI - [Dynamics of vitamin B12 in cerebrospinal fluid (author's transl)]. PMID- 4209027 TI - Novel human serum protein from fibroblast plasma membrane. PMID- 4209028 TI - Review: The endocrine glands in infantile malnutrition. PMID- 4209030 TI - Proceedings: Immunoglobulins in early syphilis. PMID- 4209029 TI - Oxidation of phenols by cells and cell-free enzymes from Candida tropicalis. PMID- 4209031 TI - The influence of repeated and prolonged stimulation on the PHA-response of lymphocytes in Hodgkin's disease. PMID- 4209032 TI - Enhanced uptake of anti-Rho coated red cells by cultured human monocytes. PMID- 4209033 TI - [Modification of blood platelets during decompression accidents]. PMID- 4209034 TI - Lysozyme-negative, peroxidase-positive mononuclear cells: a new kinetically distinct cell population in normal rat blood. PMID- 4209035 TI - Splenic feedback in red cell regeneration. PMID- 4209036 TI - 'Nonsecretory' multiple myeloma. Report of a case. PMID- 4209037 TI - [A case of mandibulofacial dysostosis (Franceschetti) and a review of the Literature]. PMID- 4209040 TI - Grey scale echography in the diagnosis of intrahepatic disease. PMID- 4209038 TI - Effect of glucose on the biosynthesis of the membranes of Bacillus. PMID- 4209039 TI - Effects of ions on vesicles and phospholipid dispersions studied by polarization of fluorescence. PMID- 4209041 TI - Ultrasound studies in premature infants after birth. PMID- 4209042 TI - Letter: Fetal biparietal diameters correlated with gestational age. PMID- 4209043 TI - Proceedings: Studies on glucuronic acid metabolism: effect of uridine diphosphate glucuronic acid and thiol groups on the enzymes in the glucuronic acid metabolism series. PMID- 4209044 TI - Proceedings: Possible mechanism of action of methyldopa: relationship studies between route on administration, dose, plasma concentration and hemodynamic changes in conscious monkeys. PMID- 4209045 TI - Proceedings: Studies on drug dependence report. 19: quantitative evaluation of reinforcing effect on drug-seeking behavior. PMID- 4209046 TI - Epidemiologic aspects of nontuberculous mycobacterial disease and of tuberculosis in British Columbia. PMID- 4209047 TI - UV irradiation of poplar cells of Drosophila melanogaster embryos. V. A study of the meiotic recombination in females with chromosomes of different structure. PMID- 4209048 TI - Evidence for two immunologically distinct acetyl-co-enzyme A synthetase in yeast. PMID- 4209049 TI - Effect of photooxidation of bacterial liquefying alpha-amylase dependent on the degree of polymerization of linear substrates. PMID- 4209050 TI - Population genetics in the American Tropics. IX. Rhythmic genetic changes that prove the adaptive nature of the detrimental load in Drosophila melanogaster from Caracolisito, Colombia. PMID- 4209051 TI - Metabolism of lysolecithin in vivo and in vitro with particular emphasis on the arterial wall. PMID- 4209052 TI - In vitro activity of cephalosporins against Mycobacterium tuberculosis H37Rv: structure-activity relationships. PMID- 4209053 TI - Degradation of tuberculoproteins by cathepsin D-type proteinase of alveolar and peritoneal macrophages of mice. PMID- 4209054 TI - Slime production by Pseudomonas aeruginosa. IV. Chemical analysis of two varieties of slime produced by Pseudomonas aeruginosa. PMID- 4209055 TI - Stability of frozen solutions of cephapirin sodium. PMID- 4209056 TI - Diethylpropion hydrochloride (Tenuate Dospan) in combination with hypotensive agents in the treatment of obesity associated with hypertension. PMID- 4209057 TI - Tobramycin therapy of pulmonary infections in patients with cystic fibrosis. PMID- 4209058 TI - Clinical experience with doxycycline in the treatment of surgical soft-tissue infections. PMID- 4209059 TI - Treatment of otitis externa: a controlled bacteriological-clinical evaluation. PMID- 4209060 TI - Prevention of swimmer's ear by simple prophylactic regimen. PMID- 4209061 TI - Tolmetin versus placebo for the treatment of rheumatoid arthritis: a sequential double-blind clinical trial. PMID- 4209062 TI - Doxepin versus amitriptyline in depression: a sequential double-blind study. PMID- 4209063 TI - An early clinical trial of lenperone (AHR 2277), a butyrophenone, in chronic schizophrenia. PMID- 4209065 TI - [Ganglion cell types in the retino-tectal projection in the toad Bufo bufo (L.)]. PMID- 4209064 TI - Effect of CDP-choline in experimental cerebral hemorrhage. PMID- 4209066 TI - [Long-term treatment of cerebrovascular stroke]. PMID- 4209067 TI - Antibiotic disk susceptibility tests with Neisseria gonorrhoeae. AB - We have used a standardized disk diffusion procedure to test the susceptibility of 892 isolates of Neisseria gonorrhoeae to six antibiotics. The disk diffusion test described is a modification of the disk test of Bauer, Kirby, Sherris, and Turck, which is widely used for susceptibility testing of fast-growing, aerobic pathogens. With all six antibiotics (penicillin, ampicillin, tetracycline, erythromycin, chloramphenicol, and cephaloridine), disk test results were found to be reproducible and correlated well with the minimal inhibitory concentration as determined by an agar dilution procedure. The coefficients of correlation ranged from -0.79 with cephaloridine to -0.93 with penicillin. The technique described for disk susceptibility testing of gonococci can be used both for research and clinical purposes. PMID- 4209068 TI - Semiautomated turbidimetric microbiological assay for determination of cefazolin. AB - The Autoturb System, a semiautomated system for photometric bioassay, was used to determine cefazolin content. Suitable conditions for the assay using Streptococcus faecalis ATCC 10541 as the indicator organism included a medium pH of 6.0 to 7.0 and an incubation time of 3 to 3.5 h at 36 C. Multiple independent assays of samples from a common batch showed the test to be highly reproducible. Accuracy of the turbidimetric assay was evaluated by comparing data obtained from a chemical (hydroxylamine) and a biological (disk diffusion) assay. The available data show the turbidimetric assay to be a rapid, accurate, and reproducible method for determining the biological activity of cefazolin samples. PMID- 4209069 TI - Dissociation between results of in vitro and in vivo antibiotic susceptibility tests for some strains of Pseudomonas aeruginosa. AB - The relative efficacy in vivo of the polymyxin and aminoglycoside antibiotics in experimental Pseudomonas infection has apparently never been established. This study was designed to determine such efficacy in experimental infection of mice. Eleven strains of Pseudomonas aeruginosa were selected for the study, representing six of the seven recognized immunotypes. All strains were susceptible to colistin, gentamicin, and tobramycin in vitro, and all were virulent for mice. None was lethal because of preformed toxins. Infections were established in mice by intraperitoneal (i.p.) injection of 100 ID(50) of bacteria (infectious doses that would kill 50% of the mice). Graduated doses of antibiotics or saline were given subcutaneously 1 h later. Infections by three strains of P. aeruginosa were cured by low doses of all three antibiotics. Infections by two strains were relatively resistant in vivo to all three antibiotics. Infections by seven strains were relatively resistant in vivo to colistimethate. For most strains, colistimethate was less effective in vivo than gentamicin or tobramycin. To determine the influence of the size of the bacterial inoculum upon the results of chemotherapy, groups of mice were infected with serial dilutions of bacterial suspensions and treated with antibiotics. The antibiotics were more effective when a lighter bacterial inoculum was used. However, colistimethate at 30 mg/kg failed to cure some infections established with an inoculum of only 10 ID(50). To examine the possibility that death despite apparently adequate chemotherapy might be due to bacterial lysis and delayed release of toxins, numbers of viable bacteria in the peritoneal cavity of treated animals were determined by colony count. Antibiotic failure by colistimethate was associated with a steady rise in the number of i.p. bacteria. The findings support the conclusion that i.p. infections in mice with some strains of P. aeruginosa that are fully susceptible in vitro are relatively resistant to chemotherapy in vivo. The dissociation between in vitro and in vivo results was greatest for colistimethate. PMID- 4209070 TI - Biological assay of streptonigrin (NSC 45383) in body fluids and tissues of mice. AB - Streptonigrin, a quinone antitumor antibiotic, has been reported to be effective in human trials. A sensitive and precise microbiological assay for the determination of distribution and concentrations of streptonigrin in the body fluids and tissues of treated mice has been developed in an attempt to supplement successful clinical application of this drug. PMID- 4209071 TI - Selective phosphorylation of the 5''-hydroxy group of ribostamycin by a new enzyme from Pseudomonas aeruginosa. AB - It was found that the 5''-hydroxy group of ribostamycin was preferentially phosphorylated by a cell-free extract from Pseudomonas aeruginosa GN 573, a clinical isolate. PMID- 4209072 TI - Photochemistry of bioactive compounds: photoproducts and kinetics of polychlorinated biphenyls. PMID- 4209074 TI - Diabetic ketosis. PMID- 4209075 TI - Ecology of Simuliidae, Mermithidae, and Microsporida in Newfoundland freshwaters. PMID- 4209073 TI - Physicochemical appraisal of changes in egg white during storage. PMID- 4209076 TI - The effect of extracellualr calcium on thermal excitability of the sensory units in the tooth of the cat. PMID- 4209077 TI - Idiopathic membrano-proliferative glomerulonephritis in children (corrections between light, electron, immunofluorescent microscopic appearances and serum C3 and C4 levels). PMID- 4209078 TI - Editorial: Slow virus infections. PMID- 4209079 TI - Letter: Minimal effective dosage of cromolyn. PMID- 4209080 TI - Letter: Families with high serum enzyme levels. PMID- 4209081 TI - Loss of visual suppression of vestibular nystagmus after flocculus lesions. PMID- 4209083 TI - [The new narcotics prescription order (author's transl)]. PMID- 4209082 TI - [Psychosomatic medicine of outsiders]. PMID- 4209085 TI - A study on procaine and procaine adrenaline injections of the British Pharmacopoeia 1968. PMID- 4209084 TI - [Experiments and considerations on the sterilization of thermolabile materials with peracetic acid]. PMID- 4209086 TI - Fine structure of Haemoproteus columbae Kruse during differentiation of the ookinete. PMID- 4209087 TI - Fine structure of differentiating oocysts and mature sporozoites of Haemoproteus metchnikovi in its intermediate host Chrysops callidus. PMID- 4209088 TI - Phosphorus regeneration in fresh-water paramecia. PMID- 4209089 TI - [Effect of certain agents on antigenic activity of Salmonella]. PMID- 4209090 TI - [Properties of insoluble enzymes as exemplified by glutaraldehyde-treated phosphatase]. PMID- 4209091 TI - [Some biological properties the cyclic carbonate of erythromycin A]. PMID- 4209092 TI - Beta-alanine and adaptation in Drosophila. PMID- 4209093 TI - The occurrence of vitellogenin in workers and queens of Apis mellifica and the possibility of its transmission to the queen. PMID- 4209094 TI - Precipitation of myelin basic protein by beta-lipoprotein of human serum. A study of similarities and differences of the precipitation in normal sera and sera from patients with multiple sclerosis. PMID- 4209095 TI - Cellular patterns of differing circadian rhythms and levels of RNA synthesis in Drosophila salivary glands. PMID- 4209096 TI - [Methodological principle of a method of obtaining attenuated tuberculosis vaccines]. PMID- 4209097 TI - [Comparative morphological aspects of Mycobacterium tuberculosis, classical type, and Mycobacterium africanus (preliminary note)]. PMID- 4209098 TI - [Sensitivity to antibiotics in strains of Corynebacterium diphteriae isolated at Dakar]. PMID- 4209099 TI - [Importance of determination of specific alpha-1-fetoprotein (alpha A fetoprotein) for the diagnosis of prematurity]. PMID- 4209100 TI - [Agenesis of the corpus callosum. (Apropos of 4 cases in African Negroes)]. PMID- 4209101 TI - Antigenic reactivity of inactivated Bacillus subtilis enzyme preparations. PMID- 4209102 TI - Serum IgG, IgA, IgM, and IgE levels and allergy in Filipino children in the United States. PMID- 4209103 TI - The effect of changes of dietary calcium concentration on calcium metabolism in sheep. PMID- 4209104 TI - Studies on a smooth phage-resistant variant of Brucella abortus. I. Immunological properties. PMID- 4209106 TI - Localization of thyrotropin-releasing factor (TRF) in the hypothalamus of the rat. PMID- 4209105 TI - Body retention of injected 67Cu in patients with homozygous or heterozygous Wilson's disease and in normal subjects. Comparison of whole-body counting systems. PMID- 4209108 TI - Cell survival and architectonic differentiation of the hypothalamic mamillary region of the newborn mouse in culture. PMID- 4209107 TI - Kinetics of thyroxine and triiodothyronine in a case of thyroxine-binding globulin deficiency with hypothyroidism. PMID- 4209109 TI - Fractionated action of ethylenimine on the rate of mutation in Drosophila melanogaster. PMID- 4209110 TI - Isolation and characterization of soluble and particulate thyroid iodoproteins in human congenital goiter. PMID- 4209111 TI - Proceedings: Long-term toxicity study of methylmercuric chloride in monkeys. PMID- 4209112 TI - Major urinary protein and immunoglobulin allotypes of recombinant inbred mouse strains. PMID- 4209113 TI - Proceedings: Pharmacological studies on polychlorobiphenyl (PCB). 3. Effect on the content and metabolism of vitamin B2 and B6, and ascorbic acid in various organs of the rat. PMID- 4209114 TI - [Pathogenicity of lactobacilli]. PMID- 4209115 TI - The impact of chemotherapy on the care of patients with tuberculosis. PMID- 4209116 TI - Health problems and medical care in Papua New Guinea. PMID- 4209117 TI - Sex-linked auxotrophic and putative auxotrophic mutants of Drosophila melanogaster. AB - Thirty-two mutants with improved growth response on a yeast-sucrose compared with a defined medium have been characterized with respect to ribonucleoside supplementability. Twenty mutants respond to either pyrimidine ribonucleoside. Four mutants respond to one or both purine ribonucleosides. Eight mutants ("putative" auxotrophs) do not respond to dietary RNA supplementation. Mapping and complementation studies suggest that eleven loci are represented: one, rudimentary, probably accounts for all pyrimidine requirers; there are three purine loci and seven at which the putative auxotrophs are found. PMID- 4209118 TI - Development in genetic mosaics of aristapedia, a homoeotic mutant of Drosophila melanogaster. AB - Development of the homoeotic mutation, aristapedia (ss(a)), was investigated by means of genetic mosaics. The wild-type alleles of aristapedia and the bristle markers yellow, singed, and forked were removed from cells at different times in development by X-ray induced somatic crossing-over. The phenotype of the resulting clones was examined in order to ascertain whether it was leg or antenna. The y sn f; ss(a) clones showed a leg phenotype if induced before the mid-third instar, but showed an antennal phenotype if induced after this time. Late non-expression of ss(a) may be due either to an influence of surrounding ss(+) tissues on the small ss(a) clones, or to a persistence of the effect of ss(+) for one or two cell generations after it is removed from a cell line. PMID- 4209119 TI - [Sporulation in temperature-sensitive mutants of Bacillus subtilis for initiation of DNA synthesis]. PMID- 4209120 TI - Chemistry of wheat proteins and the nature of the damaging substances. PMID- 4209121 TI - Congenital lactose intolerance of gastrogen origin associated with cataracts. PMID- 4209123 TI - Aflatoxins in foods and feedstuffs. 3. Fluorodenisitometric method for determination of aflatoxins M1 and M2 in presence of aflatoxins B1, B2, G1, and G21. PMID- 4209122 TI - Anthyridine and 1,10,11,12-tetraazanaphthacene derivatives: synthesis and biological properties. PMID- 4209124 TI - [Results of conservative treatment of ankle-joint injuries with participation of syndesmosis]. PMID- 4209125 TI - [Pharmacokinetic and chemoprophylactic studies with berenil in macaques (trypanosoma rhodesiense-infection) (author's transl)]. PMID- 4209127 TI - Camazepam versus diazepam: a double-blind study during endoscopy inspection. PMID- 4209126 TI - Study of a new antihypertensive (guanabenz). PMID- 4209128 TI - Visual suppression of vestibular nystagmus in rhesus monkeys. PMID- 4209129 TI - Traumatic lesions of the ankle joint. The supination-external rotation mechanism. PMID- 4209130 TI - Familial IgA defects. PMID- 4209131 TI - [Radiological diagnosis of hypertension (author's transl)]. PMID- 4209133 TI - [Renal hypertension (author's transl)]. PMID- 4209132 TI - [Hypertension in pregnancy (author's transl)]. PMID- 4209134 TI - [Catalytic psychotherapy (author's transl)]. PMID- 4209136 TI - Microbial models of mammalian metabolism. Aromatic hydroxylation. PMID- 4209135 TI - [Results of the schistosomicidal activity of an organophosphorus compound, metrifonate, in urinary bilharziasis]. PMID- 4209137 TI - Changes in conformation and nucleotide binding of Ca, Mn, or MgG-actin upon removal of the bound divalent cation. Studies of ultraviolet difference spectra and optical rotation. PMID- 4209139 TI - Lymphocyte-macrophage interaction in resistance to Listeria momocytogenes. PMID- 4209141 TI - Protein calorie malnutrition: a major health problem of multiple causation in Malaysia. PMID- 4209138 TI - Accumulation of 3H-1-lysine by brain and plasma in male and female rats treated acutely wigh morphine sulfate. PMID- 4209140 TI - Scrub typhus antibody in mammals in three habitats in Sabah. PMID- 4209142 TI - The molecular biology of Euglena gracilis. IX. Amino acid pool composition. PMID- 4209143 TI - The estimation of serum cholinesterase in the presence of anti-cholinesterase insecticides. PMID- 4209144 TI - Antibodies against different viral antigens in cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases. PMID- 4209145 TI - Physiologic and pathophysiologic relationship between the electroencephalogram and the regional cerebral blood flow. PMID- 4209146 TI - [Serotypes of Pseudomonas aeruginosa strains recently isolated at Dakar]. PMID- 4209147 TI - [Clinical evaluation of the effect of DSCG on allergic dyspnea in children (author's transl)]. PMID- 4209148 TI - Multiple myeloma. I. Clinical, biochemical and immunochemical aspects. PMID- 4209149 TI - The ultrastructure of melanoma cells treated with 5-bromodeoxyuridine. PMID- 4209150 TI - [Diagnosis and treatment of portal hypertension]. PMID- 4209151 TI - Cannabis: a psychopharmacological review. PMID- 4209152 TI - [Acid-base balance and oxygen-binding patterns of erythrocytes in severe diabetic ketoacidosis]. PMID- 4209154 TI - Browning of the lens in generalized albinism. PMID- 4209153 TI - [Insulin secretion in terminal renal insufficiency and following chronic intermittant hemodialysis]. PMID- 4209155 TI - Circulating autoantibodies in ocular pemphigoid. PMID- 4209156 TI - The production of antibodies against mammalian LDH-1. PMID- 4209157 TI - Hydroxyapatite column chromatography in procedures for isolation of purified DNA. PMID- 4209158 TI - Testicular lesions in rats treated for one year with ethambutol in low doses. PMID- 4209159 TI - Hepatic blood flow and portal vein pressure during intravenous infusion of amino acids in dogs. PMID- 4209161 TI - Stereotactic amygdaloidotomy for aggressive behaviour. AB - Amygdaloidotomy was performed bilaterally on 15 and unilaterally on three patients exhibiting severe aggressive or self-mutilating behaviour. Nine subjects (50%) were improved a year after operation; improvement was maintained in seven (39%) for periods ranging from 27 months to nearly six years. Four non-epileptic cases had convulsions during the period of review; one of them has a persistent mild hemiparesis dating from the postoperative period. There was a tendency for epileptics to respond better than non-epileptics and for mentally retarded patients to respond poorly, but none of the differences was statistically significant. PMID- 4209160 TI - Raised intracranial pressure and cerebral blood flow. 3. Venous outflow tract pressures and vascular resistances in experimental intracranial hypertension. AB - Pressure changes within the venous outflow tract from the brain were studied in anaesthetized baboons. Segmental vascular resistance changes were also calculated and the results correlated with the changes in cerebral blood flow, measured by the (133)Xenon clearance method. Three different methods were used to raise intracranial pressure: cisterna magna infusion, a supratentorial subdural balloon, and an infratentorial subdural balloon. A close correlation was found between the cortical vein pressure and intracranial pressure with all methods of raising intracranial pressure: the overall correlation coefficient was 0.98. In the majority of animals sagittal sinus pressure showed little change through a wide range of intracranial pressure. In three of the six animals in the cisterna magna infusion group, however, sagittal sinus pressure increased to levels approaching the intracranial pressure during the later stages of intracranial hypertension. Jugular venous pressure showed little change with increasing intracranial pressure. The relationship between cerebral prefusion pressure and cerebral blood flow differed according to the method of increasing intracranial pressure. This was due to differing patterns of change in prevenous vascular resistance as venous resistance increased progressively with increasing pressure in all three groups. The present results confirm, therefore, the validity of the current definition of cerebral perfusion pressure-that is, cerebral perfusion pressure is equal to mean arterial pressure minus mean intracranial pressure-by demonstrating that intracranial pressure does represent the effective cerebral venous outflow pressure. PMID- 4209162 TI - [Rare obstructive diseases of the distal ureter (author's transl)]. PMID- 4209163 TI - [Autoradiographic study of the replication state in the sporangium and spore nucleus of Bacillus subtilis]. PMID- 4209164 TI - Intestinal alkaline phosphatase. Physical properties and quaternary structure. PMID- 4209165 TI - Isocitrate lyase from the free-living nematode, Tubatrix aceti: purification and properties. PMID- 4209167 TI - Energetics and spectral changes in ligand binding by homogeneous rabbit anti lactose antibody. PMID- 4209166 TI - Effects of abnormal base ionizations on Mg2 plus binding to transfer ribonucleic acid as studied by a fluorescent probe. PMID- 4209169 TI - [Comparative studies of physico-chemical and immunological methods for determination of fibrinogen (simplified micromethod for determination of fibrinogen)]. PMID- 4209168 TI - [Taxonomy of gram-positive immobile Diplobacilli isolated from necrotizing nephroses in the American char and rainbos trout]. PMID- 4209170 TI - Proceedings: Evaluation of a rat thyrotrophin radioimmunoassay and its applications. PMID- 4209172 TI - Current understanding of human prolactin physiology and its diagnostic and therapeutic applications: a review. PMID- 4209173 TI - Hydrolysis of casein by three extracellular proteolytic enzymes from Staphylococcus aureus, strain V8. PMID- 4209175 TI - The formation of a calcium-dependent extracellular proteolytic enzyme from Staphylococcus aureus. PMID- 4209174 TI - The role of calcium for stability and activity of an extracellular proteolytic enzyme from Staphylococcus aureus. PMID- 4209176 TI - Agglutinins against group 3 atypical mycobacteria. PMID- 4209177 TI - Immune response to Mycobacterium leprae in indeterminate leprosy patients. PMID- 4209178 TI - Rabbit anti rat lymphocyte serum: immunosuppression mediated by a pure IgM fraction. PMID- 4209180 TI - Relation between fragments after oblique sliding osteotomy of the mandibular rami and its influence on postoperative conditions. PMID- 4209181 TI - An orthopantomographic study of developmental mandibular bone defects (Stafne's idiopathic bone cavities). PMID- 4209179 TI - Cellular and humoral pathways in the neuroendocrine regulation of reproductive function. PMID- 4209182 TI - The composition of several commercial rapid tube and saline anti-D reagents. PMID- 4209183 TI - The relationship between hyphal branching, specific growth rate and colony radial growth rate in Penicillium chrysogenum. PMID- 4209184 TI - Editorial: Coming of age of medical primatology. PMID- 4209185 TI - Studies on menstrual blood loss in intact and experimental rhesus monkeys. PMID- 4209186 TI - Blood groups of mountain gorillas (Gorilla gorilla beringei). PMID- 4209187 TI - Comparative study of radiosensitivity of peripheral blood lymphocyte chromosomes of Macaca mulatta at different doses of irradiation. PMID- 4209188 TI - Ultrastructural observations on scrapie in the gerbil. PMID- 4209189 TI - Inoculation of cattle with bovine lymphoid cell lines infected with Theileria annulata. PMID- 4209190 TI - African swine fever: comparison of four serotests on porcine serums in Spain. PMID- 4209191 TI - [Endocarditis caused by Pseudomonas aeruginosa (author's transl)]. PMID- 4209192 TI - [Therapy of thyroid crises]. PMID- 4209193 TI - Woodruffia metabolica: an exception to the rule of desmodexy. AB - Woodruffia metabolica (Protozoa, Ciliophora) has a compound fiber on the left side of its ciliary rows composed of parallel, overlapping ribbons of kinetosome based microtubules. No similar structure is found connecting the kinetosomes on the right side of the ciliary rows. This arrangement is in opposition to the rule of desmodexy. PMID- 4209194 TI - To the possible spread of scabies through bed linen. PMID- 4209196 TI - Glycogen synthetase and phosphorylase in developing chick glycogen body. PMID- 4209195 TI - Pair formation in tetrahymena pyriformis, an inducible developmental system. PMID- 4209197 TI - [Pulmonary phakomatosis]. PMID- 4209199 TI - Community health education: a challenge to hospital and medical staffs. PMID- 4209198 TI - [Generalization of the mitochondrial cycle in synchronous Euglena gracilis Z. during heterotrophic and phototrophic growth]. PMID- 4209201 TI - Immunologic reactivity in rabbits remotely deprived of the sacculus rotundus. PMID- 4209202 TI - Conductance of active and passive pathways in the toad bladder. PMID- 4209204 TI - Evolution of a facilitated diffusion pathway for amides in the erythrocyte. PMID- 4209203 TI - Aldosterone stimulation of acidification of urine by isolated urinary bladder of the Colombian toad. PMID- 4209200 TI - Control of cell division in bacteria. PMID- 4209206 TI - Spatial distribution of human cell survival and oxygen effect in a therapeutic helium ion beam. PMID- 4209208 TI - Spatial distribution of human cell survival in a neutron bean designed for therapy. PMID- 4209207 TI - ISAH: a versatile treatment positioner for external radiation therapy. PMID- 4209205 TI - Stimulation by amphotericin B of active Na transport across amphibian cornea. PMID- 4209210 TI - Radiation therapy of Hodgkin's disease: significance of splenic involvement. PMID- 4209209 TI - Experience with fast neutron therapy usine the Texas A and M variable energy cyclotron. PMID- 4209212 TI - Hallucinogens as discriminative stimuli. PMID- 4209211 TI - Theoretical explanations of drug-dissociated behaviors. PMID- 4209214 TI - Proceedings: 314. Group I activated neurons of 3a area and voluntary forearm movement in the monkey. PMID- 4209213 TI - Experimental inhibition of serotonin by antibiotic: prevention of cerebral vasospasm. PMID- 4209215 TI - Proceedings: 320. Visuokinetic neurons of the prefrontal cortex and delayed response. PMID- 4209216 TI - Proceedings: 362. Response of the amphibian papilla nerve in the toad bufomarinus. PMID- 4209217 TI - Continuous nasogastric infusion feedings of infants of low birth weight. PMID- 4209218 TI - Feeding the low birth weight infant: orally or parenterally? Preliminary results of a comparative study. PMID- 4209219 TI - Prenatal diagnosis and selective abortion for anencephaly and spina bifida. PMID- 4209220 TI - Simple method for detecting amylase inhibitors in biological materials. PMID- 4209221 TI - Interferon response of the fetal Rhesus monkey after viral infection. PMID- 4209222 TI - Surface pattern of some microsporidian spores as seen in the scanning electron microscope. PMID- 4209223 TI - The protozoan flora of potable water from natural sources and its sub-clinical implications. PMID- 4209224 TI - Effects of age on the susceptibility of larvae and nymphs of Ixodes ricinus (L.) to insecticides. PMID- 4209225 TI - Bladder diverticula in infants and children. PMID- 4209226 TI - High pressure voiding urethrography. Principle and technique. PMID- 4209227 TI - Nitrogen metabolism and ultrastructure in Anabaena cylindrica. I. The effect of nitrogen starvation. PMID- 4209228 TI - Photochemical disproportionation of sulfur into sulfide and sulfate by Chlorobium limicola forma thiosulfatophilum. PMID- 4209229 TI - [Blood groups and personality (author's transl)]. PMID- 4209230 TI - [Blood group and illnesses. Study of the distribution of ABO blood groups in healthy volunteers compared with that in patients with psychiatric, organic and psychosomatic illnesses (author's transl)]. PMID- 4209231 TI - [Inadequate action of parenteral alimentation on insulin secretion and the control of feeding behavior in the rat]. PMID- 4209232 TI - [Trial at the use of isoelectric focusing in animal and vegetal taxonomy]. PMID- 4209233 TI - [Letter: Prolonged parenteral feeding and lecithins]. PMID- 4209234 TI - Prolactin and mental illness. PMID- 4209235 TI - A Welsh forensic psychiatric service for doctors. PMID- 4209236 TI - [Liberation of molecular hydrogen by cultures of blue-green algae]. PMID- 4209237 TI - Oculofacial anomalies and corneal ulceration. PMID- 4209238 TI - rDNA magnification at the bobbed locus of the Y chromosome in Drosophila melanogaster. PMID- 4209239 TI - [Pharyngoesophageal diverticulum. Analysis of the clinical patterns, surgical management and results of the treatment]. PMID- 4209241 TI - [Some observations on conjugation in Spirochona gemmihara Stein (Chonotrich ciliate). (With 4 figures in the text and 4 plates)]. PMID- 4209240 TI - [Extrinsic stenosis of the aqueduct of Sylvius and Recklinghausen's disease]. PMID- 4209242 TI - [Diabetic acidosis]. PMID- 4209244 TI - Management of depressed fractures of the skull. PMID- 4209243 TI - Protein-calorie malnutrition in Fiji (a clinical survey of malnourished children, admitted to the Colonial War Memorial Hospital, Suva). PMID- 4209245 TI - Aeruginocin tolerant mutants of Pseudomonas aeruginosa. PMID- 4209246 TI - [Therapy of angina pectoris. V. Various drugs. Surgical therapy and other therapeutic measures. General considerations]. PMID- 4209247 TI - Beta2-microglobulin: occurrence in fetal life and malignancy. PMID- 4209250 TI - [Influence of the environment on the growth and formation of the human skull]. PMID- 4209249 TI - Metallic copper as an intrauterine contraceptive agent. PMID- 4209248 TI - Evidence for membrane cholesterol as the common binding site for cereolysin, streptolysin O and saponin. PMID- 4209251 TI - [Detection of Dipterex as well as partially decomposed DDVP preparation by way of ascending disc and 2-dimensional chromatography]. PMID- 4209252 TI - [Comparison of various media for the isolation of Pseudomonas aeruginosa from foodstuffs]. PMID- 4209253 TI - [Early local relapse of breast carcinoma. Comparative study on 5 different irradiation technics in 368 patients]. PMID- 4209255 TI - [Present-day principles of cytostatic therapy of acute leukemia]. PMID- 4209254 TI - Vasopressin release from the isolated neurohypophysis induced by a calcium ionophore, X-537A. PMID- 4209256 TI - An evaluation of 1-(4-methyl) 2, 5-dimethoxyphenyl-2-aminobutane (MDPA-1) as an enhancer of memory and learning. PMID- 4209257 TI - Prolonged parenteral nutrition in the home. PMID- 4209258 TI - Fatty acid-induced tuberculocidal activity in sera of guinea pigs treated with bacillus Calmette-Guerin and lipopolysaccharide. PMID- 4209259 TI - The small intestinal lesion induced by Hawaii agent acute infectious nonbacterial gastroenteritis. PMID- 4209260 TI - Fetal malnutrition. PMID- 4209261 TI - Chemistry and enzymology of kcat inhibitors. PMID- 4209262 TI - Methylmalonic acid excretion studies. PMID- 4209263 TI - A thin, flat, parallel plate ionization chamber for electron beam depth-dose measurements. PMID- 4209264 TI - Histones of Drosophila embryos. Electrophoretic isolation and structural studies. PMID- 4209265 TI - Activation of succinate dehydrogenase by FMNH2 and by photoreduction. PMID- 4209266 TI - Role of myosin light chains in calcium regulation. PMID- 4209267 TI - Site of attachment of J chain to human immunoglobulin M. PMID- 4209269 TI - Partial characterisation of Escherichia coli haemolysin. PMID- 4209268 TI - Trimethoprim-sensitivity testing and thymineless mutants. PMID- 4209270 TI - Diagnosis of subacute sclerosing panencephalitis by serial tissue co-cultivation. PMID- 4209271 TI - Thyrotropin-releasing hormone: regional distribution in rat brain. AB - A sensitive and specific radioimmnunoassay has been used to measure the distribution of thyrotropin-releasing hormone (TRH) in rat brain. All areas of brain tested, except cerebellum, contained readily measurable amounts of TRH. The hypothalamus contained only 31.2 percent of the total brain content of TRH. These results support recent suggestions of central actions for TRH in addition to its hypophysiotropic functions. PMID- 4209272 TI - Thyrotropin-releasing hormone in specific nuclei of rat brain. AB - The regional distribution of thyrotropin-releasing hormone (TRH) in rat brain was studied. The greatest concentration of TRH was found in the median eminence. High concentrations were also found in several hypothalamic nuclei. Outside the hypothalamus, relatively large amounts of TRH were found in the septal and preoptic areas. PMID- 4209273 TI - Symptomatic arachnoid diverticula. PMID- 4209274 TI - Periventricular leukoencephalopathy in the monkey. A search for the "normal control" and the "early lesion". PMID- 4209275 TI - Hypothalamic releasing factors and Parkinson disease. PMID- 4209276 TI - The nature of Encephalitozoon brumpti Coulon, 1924. PMID- 4209277 TI - Effects of L-tryptophan, L-3, 4, dihydroxyphenylalanine and tranylcypromine on the electroencephalogram and on photically induced epilepsy in the baboon, Papio papio. PMID- 4209279 TI - Rebound eating following carbachol-induced drinking in rats. PMID- 4209278 TI - Equine infectious anemia. PMID- 4209280 TI - A contact detection system for identifying individual animals in groups. PMID- 4209281 TI - Activities of DNA degrading enzymes in the slime mold Physarum polycephalum. Evidence for five different enzymes. PMID- 4209282 TI - The effect of fixation on the wave propagation of the protozoan axostyle. PMID- 4209283 TI - Utile and futile cycles in the liver. PMID- 4209284 TI - Enhanced specificity of epinephrine binding by rat liver plasma membranes in the presence of EDTA. PMID- 4209285 TI - Are segments of chloroplast DNA differentially amplified? PMID- 4209287 TI - Ultrastructural localization of cell wall teichoic acids in Streptococcus faecalis by means of concanavalin A. PMID- 4209286 TI - Calcium ion regulation of flagellar beat symmetry in reactivated sea urchin spermatozoa. PMID- 4209288 TI - The influence of EDTA on the composition of alginate synthesized by Azotobacter vinelandii. PMID- 4209289 TI - The basic nuclear proteins of the cellular slime mold Dictyostelium discoideum. PMID- 4209290 TI - [Generalization function in monkeys (physiological aspect)]. PMID- 4209291 TI - Lung contamination by Ce and La. Evolution of the early spontaneous absorption as a function of the initial lung burden. PMID- 4209292 TI - Retention of inhaled antimony-124 in the beagle dog as a function of temperature of aerosol formation. PMID- 4209293 TI - Investigations on radiosensitive and radioresistant populations of Drosophila melanogaster. IV. The genetics of the relative radioresistance in stage-7 oocytes of the irradiated population RO I. PMID- 4209294 TI - The induction of aneuploidy by colcemid fed to Drosophila melanogaster females. PMID- 4209295 TI - Heterologous interchange and non-disjunction of distributively paired chromosomes in Drosophila melanogaster: immature oocytes. PMID- 4209296 TI - Genetically significant dose from beam therapy in Japan, 1971. PMID- 4209297 TI - Growth of surface colonies of the gliding bacterium Myxococcus xanthus. PMID- 4209298 TI - Participation of two photosystems in the photo-phobotaxis of Phormidium uncinatum. PMID- 4209299 TI - Indentification of a pH 6.5 acetohydroxyacid synthetase in Bacillus subtilis. PMID- 4209300 TI - Ozone effects on chlorophylls a and b. PMID- 4209301 TI - The reproductive cycle of the gelada baboon. PMID- 4209302 TI - [Etiology and pathologic anatomy of salpingitis]. PMID- 4209303 TI - [Duodenal diverticula]. PMID- 4209304 TI - [Carbonic anhydrase and inhibition of gastric secretion by acetazolamide]. PMID- 4209306 TI - Tobacco budworm: chemosterilization by fumigation with thiotepa. PMID- 4209305 TI - [Interpretation possibilities of the presence of Australia antigen (Au. an.) in patients with chronic hepatitis and hepatic cirrhosis]. PMID- 4209307 TI - Corynebacterium diphtheriae infections in Tanzania. PMID- 4209308 TI - Immunisation of marmoset monkeys with a killed oncogenic herpesvirus. PMID- 4209310 TI - Intraluminal duodenal diverticulum. PMID- 4209311 TI - Effect of anti-C4 on cellular synthesis of C4 by guinea pig peritoneal macrophages, pulmonary macrophages, liver or spleen cells. PMID- 4209309 TI - [External drainage of biliary tract]. PMID- 4209312 TI - Isolation and properties of recombination-deficient mutants of Pseudomonas aeruginosa. PMID- 4209313 TI - Localization of chemically induced breaks in chromosomes of human leucocytes. PMID- 4209314 TI - Preparation of penicillin N and isopenicillin N. PMID- 4209315 TI - Recent studies on the origins of cellular organelles. PMID- 4209316 TI - Studies of ribosomal diffusion coefficients using laser light-scattering spectroscopy. AB - Using an optical beating technique, the diffusion coefficients and relative scattered intensity of Escherichia coli 70S, 50S, and 30S ribosomes are measured as a function of temperature and Mg(2+) concentration. For solutions at 10 mM Mg(2+) and between 0 degrees C and about 40 degrees C, the values of D(20,w) obtained are 1.7, 1.9, and approximately 2.1 x 10(-7) cm(2)/s, respectively. Preparative procedures drastically affect these values and equivalent hydrodynamic ellipsoids of revolution models give large axial ratios indicating extensive hydration or a deviation from the assumed shape. Calculations also indicate that the subunits expand upon dissociation. Measurements of D(20,w) vs. temperature indicate that 70S particles undergo a conformational change prior to dissociation and can be heat dissociated at 30-32 degrees C at low concentrations. Treatment of 70S ribosomes with EDTA causes a biphasic dissociation reaction. Addition of Mg(2+) after dissociation with EDTA shows that longer waiting times yield fewer 70S particles and that even short waiting times may yield ribosomes differing from the native conformation. Addition of p chloromercuribenzoic acid (PCMB) is shown to dissociate 70S particles, but to a lesser extent than ethylenediaminetetraacetic acid (EDTA). PMID- 4209317 TI - Serologic recognition of the histocompatibility antigens using agglutination and cytotoxicity techniques. PMID- 4209318 TI - Glucose-6-phosphate dehydrogenase Jackson. A new variant associated with hemolytic anemia. PMID- 4209319 TI - Cell wall alterations of gram-negative bacteria by aminoglycoside antibiotics. AB - After treatment with aminoglycoside antibiotics, Escherichia coli B and Pseudomonas aeruginosa P28 showed numerous blebs on the cell wall surface. PMID- 4209320 TI - [Esophageal obstruction by mucilage]. PMID- 4209321 TI - Complement-mediated changes in morphology of hepatitis B antigen-antibody complexes. PMID- 4209322 TI - Differences between Bombay and Rhnull phenotypes. PMID- 4209323 TI - Time-related changes in reaction determining hepatitis B antigen in viral hepatitis patients. PMID- 4209324 TI - Differentiation of Drosophila neuroblasts to form ganglion-like clusters of neurons in vitro. PMID- 4209325 TI - The effect of humoral agents on the cranial circulation of the monkey. PMID- 4209326 TI - In vitro immunological characteristics of lymphoid cells derived from owl monkeys infected with Herpesvirus saimiri. PMID- 4209327 TI - Immunological and virological investigations on owl monkeys infected with Herpesvirus saimiri. PMID- 4209328 TI - Chemotherapy of Herpesvirus saimiri induced lymphoma-leukemia in the owl monkey. PMID- 4209329 TI - Specificity differentiation (SPD) of oncogenic and non-oncogenic herpesviruses by immunofluorescence. PMID- 4209330 TI - Immunochemical quantitation of dextran by a polymer enhanced nephelometric procedure. PMID- 4209331 TI - Cortisone-resistant thymocytes as target cells in lymphocyte-mediated cytolysis. PMID- 4209332 TI - Iron absorption from maize. Effect of ascorbic acid on iron absorption from maize supplemented with ferrous sulphate. PMID- 4209333 TI - Detection of brief light flashes by monkeys (Macaca nemestrina) with dorsolateral frontal ablations. PMID- 4209334 TI - The effects of orbital and dorsolateral frontal cortical ablations on ethanol self-selection and emotional behaviors in monkeys (Macaca nemestrina). PMID- 4209335 TI - [Hearing aid or operation to improve hearing? (author's transl)]. PMID- 4209336 TI - [Cervical lymphoma: topography--diagnosis--therapy]. PMID- 4209337 TI - [Antibacterial activity of tobramycin on Pseudomonas aeruginosa]. PMID- 4209338 TI - [In vitro behavior of Pseudomonas, Serratia and Acinetobacter towards tobramycin]. PMID- 4209339 TI - [Urinary tract infections due to multiresistant gram negative bacteria]. PMID- 4209340 TI - [Immunoglobulin E in monoclonal and polyclonal hypergammaglobulinaemia (author's transl)]. PMID- 4209341 TI - [Necrosis and hyperbasophilia in the rat hepatic parenchyma]. PMID- 4209342 TI - [Changes in the treatment of callus delay and pseudarthrosis (author's transl)]. PMID- 4209343 TI - [Medical check-ups in orthopedics for the early recognition of diseases in newborn infants, infants and yound children]. PMID- 4209344 TI - [Reconstructive vascular surgery (author's transl)]. PMID- 4209346 TI - [Homologous lyophilized dura mater preparations in gingival-surgery]. PMID- 4209345 TI - [Immunosuppressive therapy of progredient chronic polyarthritis]. PMID- 4209347 TI - Composition of lipopolysaccharides from Myxococcus fulvus and other fruiting and non-fruiting myxobacteria. PMID- 4209348 TI - Membrane-bound DD-carboxypeptidase and LD-transpeptidase of Streptococcus faecalis ATCC 9790. PMID- 4209350 TI - Reactive hyperaemia in the dog heart: studies on mechanisms. PMID- 4209349 TI - Some kinetic properties of human-milk galactosyl transferase. PMID- 4209351 TI - [Letter: Hypoglycemia due to alcohol consumption]. PMID- 4209352 TI - Mutagenicity of reactive derivatives of carcinogenic hydrocarbons: evidence of DNA repair. PMID- 4209353 TI - Pathogenesis of anemia associated with Mycoplasma pneumoniae. PMID- 4209354 TI - Bilateral ossification of the ear canal in an American Cocker Spaniel. PMID- 4209355 TI - A rapid method for estimating microsomal oxidase activity in the housefly with (14C)parathion as substrate. PMID- 4209356 TI - [Non-neurogenic intestinal tumors in Von Recklinghausen's disease]. PMID- 4209357 TI - The immunology of experimental Chagas' disease. 3. Rejection of allogeneic heart cells in vitro. AB - Experiments that consisted of incubation of Trypanosoma cruzi-sensitized lymphocytes derived from chronically infected rabbits and from rabbits repeatedly immunized with a small particle or membrane fraction derived from homogenates of T. cruzi forms, showed destruction of allogeneic, parasitized and nonparasitized heart cells in vitro. Mononuclear cells collected from peripheral blood were incubated for 1 h at 37 degrees C to isolate the lymphocytes. Following incubation, over 99% of the cells in the supernate were lymphocytes, which were utilized in these experiments. At the start of these experiments, 70-80% of the sensitized lymphocytes were unattached, small and round, with sparse filipodia. In the ensuing hours, marked heart cell destruction, similar to that seen in an active lesion when lymphocytes invade heart tissue, were observed. After 18 h incubation, about 65-70% of the lymphocytes were attached, larger, and rough surfaced. Inhibition of monocyte migration tests, each in the presence of the antigens of subcellular fractions of T. cruzi organisms and of allogeneic heart myofibers, indicated the presence of a cross-reacting antigen common to both the parasite and the heart in the small particle or membrane fractions. The particulate antigens of the 30,000 g, 35-min fraction of heart muscle gave rise to inhibition of monocyte migration as did the counterpart fraction derived from T. cruzi organisms. The destruction of nonparasitized target heart cells by T. cruzi-sensitized lymphocytes is an in vitro model of the chronic myocarditis of Chagas' disease, and the recognition of cross-reactive antigens of the host cell by T. cruzi-sensitized lymphocytes is believed to be the pathogenic basis for subsequent tissue injury in the chronic phase of this disease. PMID- 4209358 TI - Role of meningococcal endotoxin in meningococcal purpura. AB - Enteric bacilli and meningococci (MGC) both contain potent endotoxins, but purpuric skin lesions indistinguishable from the experimental dermal Shwartzman reaction are much more common during meningococcal bacteremia than during bacteremia with enteric organisms. Highly purified lipopolysaccharides (LPS), virtually free of contamination by protein, RNA, and capsule, were extracted by a modification of the phenol-water technique from MGC (serogroups A, B, and C) and enteric bacilli (Escherichia coli 04 and 0:111, and Salmonella typhimurium). Polysaccharides in these LPS were similar by gas chromatography except for one galactose-deficient strain of MGC (135B). LPS from MGC and enterics were equally potent for the general Shwartzman reaction and mouse lethality, but LPS from MGC was 5-10 times more potent in inducing the dermal Shwartzman reaction. The greater skin potency of LPS from MGC explains the prominence of purpura in meningococcemia. Comparison of the properties of LPS may explain other differences in clinical syndromes caused by gram-negative bacteria. PMID- 4209359 TI - Restoration of mycolate synthetase activity in Mycobacterium tuberculosis exposed to isoniazid. PMID- 4209360 TI - Primary drug resistance: a continuing study of drug resistance in tuberculosis in a veteran population within the United States. X. September 1970 to September 1973. PMID- 4209362 TI - Niacin-negative Mycobacterium tuberculosis. PMID- 4209361 TI - Primary drug resistance in children. Drug susceptibility of strains of M. tuberculosis isolated from children during the years 1969 to 1972 at the Kings County Hospital Medical Center of Brooklyn. PMID- 4209363 TI - Letter: Protein calorie malnutrition, gastric motility and diabetes. PMID- 4209364 TI - [Cytoarchitectonic organization of the spinal cord in different mammals including man (author's transl)]. PMID- 4209365 TI - Evidence for cellular control in the synthesis of acetoin or alpha-ketoisovaleric acid by microorganisms. PMID- 4209366 TI - [Photoinduced absorption of hydrophobic penetrating anions by Rhodospirillum rubrum non-sulfur purple bacteria]. PMID- 4209367 TI - The influence of culture conditions on the antigenic products of Saprolegnia. PMID- 4209369 TI - Levels of serum immunoglobulins in juvenile rheumatoid arthritis. PMID- 4209368 TI - [Cytological studies on host-parasite relationships in sporozoa (Eimeria, Toxoplasma, Sarcocystis, Frenkelia, Hepatozoon, Plasmodium, and Babesia) by means of different methods (author's transl)]. PMID- 4209370 TI - Similarities between the scrapie agent and the agent of the potato spindle tuber disease. PMID- 4209372 TI - Immunoglobulin abnormalities in multiple sclerosis. PMID- 4209373 TI - [Symptomatic therapy of chronic recurrent aphthae by means of ice-cooled pellets (1st case report)]. PMID- 4209371 TI - Properties of SSPE virus; tissue culture and animal studies. PMID- 4209374 TI - Longterm clinical study with glibenclamide. PMID- 4209375 TI - Editorial: Of what measures are second generation suphonylureas? PMID- 4209376 TI - [Remote results of surgical treatment of esophageal diverticula]. PMID- 4209378 TI - Immunological and biochemical studies on fractionated bull spermatozoa. PMID- 4209377 TI - [Congenital tumors]. PMID- 4209379 TI - Whole-body counting: analysis of retention data for isotopes having prominent fecal excretion. PMID- 4209380 TI - Isolation of Trypanosoma cruzi in an acutely infected patient. PMID- 4209381 TI - A method for counting and concentrating living Trypanosoma cruzi in blood lysed with ammonium chloride. PMID- 4209382 TI - Immunity to Eimeria maxima: reactions of antisera in vitro and protection in vivo. PMID- 4209383 TI - Immunoglobulin levels in a laboratory-acquired case of human Chagas' disease. PMID- 4209384 TI - Hematozoa from Colorado birds. IV. Galliformes. PMID- 4209385 TI - A rapid method for the purification of immunoglobulin M (IgM) from the sera of certain mammalian species. PMID- 4209386 TI - Low grade osteomyelitis of the jaws-with actinomycosis. PMID- 4209388 TI - Bacteriocinogeny in the Athiorhodaceae. PMID- 4209387 TI - Adhesion of dextran to Streptococcus mutans. PMID- 4209389 TI - Evolution of reaginic antibodies in specific hyposensitization. PMID- 4209390 TI - The radioallergosorbent test (RAST) in the diagnosis of atopic allergy. PMID- 4209391 TI - Immunological studies on the blood coagulation Factor X and its warfarin-induced precursor. PMID- 4209392 TI - The relationship between blood coagulation and thrombosis and atherosclerosis in man, monkeys and carnivores. PMID- 4209393 TI - The effect of molecular iodine on platelet aggregation in vitro. PMID- 4209395 TI - Are all the Salmonella serological O factors polysaccharides? PMID- 4209396 TI - [Mediastinal-pulmonary complications during the course of phakomatoses (clinical report on 5 cases)]. PMID- 4209394 TI - Some serum globulin changes in East Coast fever. PMID- 4209397 TI - The cytogenetic analysis of a fractured gene in Drosophila. AB - The data presented in this study are derived from the analyses of Notch mutants known to be associated with visible cytological deficiencies. One mutant, Df(1)N(62b1), described as a right-side deficiency, bears a deletion that apparently initiates within the Notch locus and extends to the right as far as the locus of dm. Recombination experiments using heterozygotes of Df(1)N(62b1) with a series of intragenic point mutants within the Notch cistron suggest that this deficiency represents a deletion for the right-end portion of the gene. A consideration of the cytology of Df(1)N(62b1) supports the cytogenetic inference that, if a Notch locus-3C7 relationship is valid, the missing portion of the gene as assayed by recombination experiments has an interband position between 3C7 and 8.-The data derived from two left-side deficiencies with a genetic lesion in Notch and a deletion extending to w are somewhat equivocal, but they do support the presumed Notch locus-3C7 band relationship and thereby enhance the likelihood that Df(1)N(62b1) is correctly interpreted.-Cytogenetic information presently available suggests that, although a significant portion of the Notch cistron has a position on the salivary map identified as interband 3C7 to 8, the 3C7 band is part of the total picture of the Notch gene. PMID- 4209399 TI - [Principles of post-operative resuscitation after heart surgery in the small child]. PMID- 4209398 TI - Protein-calorie malnutrition diagnosis by hair tissue: a review. PMID- 4209400 TI - The subcellular distribution of 14C-glibenclamide in different tissues of rat. PMID- 4209401 TI - A porcine immunoglobulin Fcmu polymer that has no J chain. PMID- 4209402 TI - Characterization of the selenium in rat liver mitochondria as glutathione peroxidase. PMID- 4209403 TI - Purification of a hemagglutinin from Limulus polyphemus by affinity chromatography. PMID- 4209404 TI - A note on the use of reduced transport fluid (RTF) for isolation of Neisseria gonorrhoeae. PMID- 4209405 TI - Susceptibility of mucoid Pseudomonas aeruginosa to gentamicin disks. PMID- 4209406 TI - The radiologist in prevention and diagnosis of instrumental perforation of the esophagus. PMID- 4209407 TI - Letter: Somatostatin action on pancreas. PMID- 4209408 TI - The alcohol dehydrogenases of Drosophila melanogaster: frequency changes associated with heat and cold shock. AB - Laboratory populations of Drosophila melanogaster were subjected to heat and cold shock of sufficient duration and intensity to cause about 90 percent mortality. Alcohol dehydrogenase phenotypes were determined in survivors and controls. Significant changes in phenotypic frequencies occurred as a result of both treatments such that relative fitness appeared to be dependent on temperature. The alcohol dehydrogenase phenotype most frequently surviving heat under laboratory conditions is the same phenotype as that previously found to be higher in frequency in natural populations in areas with higher average temperature. PMID- 4209410 TI - [Mucopolysaccharidosis type II (Hurler-Hunter) in siblings. Electron microscopic study]. PMID- 4209411 TI - [Simplified penicillin dosage]. PMID- 4209409 TI - Intracellular proteolytic activity in developing myxospores of Myxococcus xanthus. PMID- 4209412 TI - [Penicillin V in two doses per day for seven days]. PMID- 4209413 TI - Hematozoa of passeriform birds from insular Newfoundland. PMID- 4209415 TI - [A method of operative treatment of chronic instability of the ankle joint (author's transl)]. PMID- 4209414 TI - Fissure sealants. Laboratory studies. PMID- 4209416 TI - Population studies on the Aland Islands. II. Historical population structure: inference from bioassay of kinship and migration. PMID- 4209417 TI - Blood groups in Zambia. PMID- 4209418 TI - Identification of the structural gene of levansucrase in Bacillus subtilis Marburg. PMID- 4209419 TI - The selection for mutants in Drosophila melanogaster hypersensitive to alpha methyl dopa, a dopa decarboxylase inhibitor. PMID- 4209420 TI - Specific recognition in gene conversion. The extent of repair synthesis in SPP1 transfection of B. subtilis. PMID- 4209421 TI - A technique for isolating the enamel organ of the rat incisor for histologic studies. PMID- 4209422 TI - Experimental study on fractures of the mandibular condylar process (mandibular condylar process fractures). PMID- 4209423 TI - Closed condylotomy in the treatment of osteoarthritis of the temporomandibular joint. PMID- 4209424 TI - A histologic study of experimentally induced periapical inflammation in primary teeth in monkeys. PMID- 4209425 TI - Treatment of oroantral communication. PMID- 4209426 TI - Absorbable synthetic suture material for internal fixation of fractures of the mandible. PMID- 4209427 TI - Aspiration cytology in the diagnosis of orofacial masses. PMID- 4209428 TI - [Diabetology and anesthesia]. PMID- 4209430 TI - An improved high-level whole-body counter. PMID- 4209429 TI - Cellular necrosis model in tissue culture: uptake of 99mTc-tetracycline and the pertechnetate ion. PMID- 4209431 TI - Iron hydroxide particle retention in primate lungs. PMID- 4209432 TI - [Plasmapheresis in the treatment of thyrotoxic crisis (author's transl)]. PMID- 4209433 TI - [Clinico-pharmacological conference]. PMID- 4209434 TI - Orosomucoid content of pleural and peritoneal effusions. AB - 22 nonneoplastic, noninflammatory effusions (cirrhosis and congestive heart failure), 12 non-neoplastic inflammatory effusions (tuberculosis, lupus erythematosus, rheumatoid arthritis, and idiopathic pleuropericarditis), and 58 neoplastic effusions (cancer of lung, breast, ovary, and pancreas, and lymphoma) were analyzed by radial immunodiffusion for orosomucoid concentration. The average concentration +/-SE was 35+/-4, 65+/-17, and 130+/-13 mg/100 ml in the three types of effusion, respectively. By gel filtration and ion exchange chromatography, orosomucoid was isolated from 12 nonmalignant and 14 malignant fluids. The orosomucoid preparations reacted as single components in acrylamide gel electrophoresis at pH 9.0, and in immunodiffusion and immunoelectrophoresis against antisera to human serum and to human plasma orosomucoid. In radial immunodiffusion, the slope of the line relating concentration to the square of the diameter of the precipitate area was identical for orosomucoid isolated from normal human plasma and from nonneoplastic effusions, but was subnormal for orosomucoid isolated from neoplastic fluids. All orosomucoid preparations had normal amino acid composition. Orosomucoid from the nonmalignant effusions had normal carbohydrate content. 11 of 14 samples of orosomucoid isolated from neoplastic fluids had abnormalities in carbohydrate composition, consisting of subnormal content of sialic acid (11 of 14), hexose (10 of 14), and hexosamine (3 of 14), and abnormally high content of hexosamine (4 of 14). Discriminant analysis showed that concentration of orosomucoid distinguished between neoplastic and nonneoplastic noninflammatory effusions more effectively than concentration of total protein, albumin, alpha(1), alpha(2), beta, or gamma globulin. PMID- 4209435 TI - Clorazepate dipotassium in the treatment of intractable epilepsy. PMID- 4209436 TI - Multiple complications and death following protriptyline overdose. PMID- 4209437 TI - Autotransfusion in the subhuman primate. PMID- 4209438 TI - Surgical management of perforated duodenal diverticula. PMID- 4209439 TI - Nonoperative roentgenologic instrumentation technics of the postoperative biliary tract. Treatment of biliary stricture and retained stones. PMID- 4209440 TI - Nitrogen and amino acid metabolism in adults with protein-calorie malnutrition. PMID- 4209441 TI - [Basic examination of cardiopulmonary system. Preventive examinations relative to general practice]. PMID- 4209442 TI - [Pulmonary vessels and pulmonary vascular changes (author's transl)]. PMID- 4209443 TI - [Acute tricuspid insufficiency resulting from rupture of the chordae tendineae (author's transl)]. PMID- 4209444 TI - [Heart catheterization and angiocardiography. Historical review and current status]. PMID- 4209445 TI - [Polyneuritis and Landry's paralysis (author's transl)]. PMID- 4209446 TI - [Exogenic toxic symptoms in the nervous system (author's transl)]. PMID- 4209447 TI - [Concomitant diseases in multiple sclerosis from the viewpoints of internal medicine and neurology. (I)]. PMID- 4209448 TI - [The late picture of a bilateral anterior cerebral occlusion with frontal lobe syndrome (author's transl)]. PMID- 4209449 TI - [Drug treatment of spasticity (author's transl)]. PMID- 4209450 TI - [Repeat intervention of the biliary tract from the internistic viewpoint]. PMID- 4209451 TI - [Reintervention of the biliary tract]. PMID- 4209452 TI - [The Fogarty catheter in biliary tract surgery]. PMID- 4209453 TI - An electron microscopic study of the intracellular development of echovirus 22. PMID- 4209454 TI - Studies on the mechanisms of influenza virus infection in hamster trachea organ culture. Correlation of reduced viral adsorption with age-related resistance to infection. PMID- 4209455 TI - Comparison of maternal and cord serum titres for measles and for rubella antibodies. PMID- 4209457 TI - Enzymic properties of diamine oxidase from hog kidney. PMID- 4209456 TI - Bovine respiratory syncytial virus: host range in laboratory animals and cell cultures. PMID- 4209459 TI - [Several cases of the jurisdiction of Federal Finance Court]. PMID- 4209458 TI - [Progress in American medicine. Current successes, current problems]. PMID- 4209461 TI - Hippocampal, hypothalamic and lateral geniculate activity during visual discrimination in the monkey. PMID- 4209460 TI - Impairments in primate information processing resulting from nitrogen narcosis. PMID- 4209463 TI - [Incidence of Au-(SH)-Ag in chronic inflammatory joint diseases]. PMID- 4209462 TI - Cell mediated lympholysis in man. A case of "non relevant" killing of third party persons. PMID- 4209464 TI - [Problems of soft calcifications from the viewpoint of internal medicine]. PMID- 4209465 TI - Carbonic anhydrase activity in the saliva of children and its relation to caries activity. PMID- 4209466 TI - [Hematological manifestations in nutritional muscular dystrophy of young cattle]. PMID- 4209467 TI - [General adaptation of piglets to the replacement of prestarters with various content of nitrogenous substances during weaning]. PMID- 4209468 TI - [Testing of a new antifungal agent in field practice]. PMID- 4209470 TI - Thyrotropin-releasing hormone in chicks. PMID- 4209471 TI - Letter: Replacement treatment of hypothyroidism. PMID- 4209469 TI - Nasal congestion as a side effect of cromolyn sodium. PMID- 4209472 TI - Stabilization and activation of a human glucose-6-phosphate dehydrogenase variant with enzyme deficiency by specific antibody. PMID- 4209473 TI - [The antibacterial activity of thyme and wild thyme oils]. PMID- 4209474 TI - Iodometric determination of penicillins using iodine monochloride. PMID- 4209475 TI - Fine structure of Haemoproteus columbae Kruse during macrogametogenesis and fertilization. PMID- 4209477 TI - [Determination of the antimicrobial activity of some acridine derivatives]. PMID- 4209478 TI - Recent advances in the pathophysiology of the parathyroid glands. PMID- 4209480 TI - [Isolation of streptococcus mutans in dental calculus and development of dental caries]. PMID- 4209476 TI - Intestinal parasite survey of kindergarten children in New Orleans. PMID- 4209482 TI - Chemotaxis toward amino acids in Bacillus subtilis. PMID- 4209481 TI - [Symposium II: The role of cord factor in tuberculosis]. PMID- 4209483 TI - Conjugation and phage MS 2 infection with Hfr Escherichia coli. PMID- 4209484 TI - Molecular heterogeneity of the bdellovibrios: metallo and serine proteases unique to each species. PMID- 4209485 TI - Autolytic activity associated with myxospore formation in Myxococcus xanthus. PMID- 4209487 TI - Algicidal effect of 2,4-dichlorophenoxy acetic acid on blue-green alga Cylindrospermum sp. PMID- 4209486 TI - Selective inhibition of plasmid DNA production in Bacillus megaterium by 6-(p hydroxy-phenylazo)-uracil: evidence for multiple maintenance systems. PMID- 4209489 TI - Proceedings: Effects of PCB administration on two generations and its chronic toxicity on the third generation in mice. 2. PMID- 4209488 TI - [Patient with septic gonococcal dermatitis syndrome]. PMID- 4209490 TI - Proceedings: Mechanism of action of circulatory drugs with regard to effects on venous return. 2. PMID- 4209491 TI - [Long-term curative treatment of occupational allergic bronchial asthma (author's transl)]. PMID- 4209492 TI - Prevention of tuberculous cavity formation by desensitization with tuberculin active peptide. PMID- 4209493 TI - Hypersensitivity lung disease in the turkey raising industry. PMID- 4209494 TI - Extrinsic allergic alveolitis owing to hypersensitivity to chickens-significance of sputum precipitins. PMID- 4209495 TI - Ontogeny of Tamm-Horsfall urinary glycoprotein. PMID- 4209496 TI - [The effect of different caloric supplements (glucose, fructose, triglycerides) on the utilisation of parenterally administered amino acids]. PMID- 4209497 TI - Serum proteins and alkaline phosphatase levels in patients with tuberous sclerosis. PMID- 4209498 TI - A calorimetric study of the binding of sulfonamides and cyanate to carbonic anhydrase. PMID- 4209499 TI - Hemoglobin S-Ga Georgia disease: a case report. PMID- 4209501 TI - Letter: Intrathoracic foregut cysts. PMID- 4209500 TI - Sodium valproate in treatment of epilepsy. AB - Sodium valproate has a simple chemical structure unlike other anticonvulsants. It has been given to 63 patients with various types of epilepsy whose attacks were frequent and of whom 40 had failed to respond to other anticonvulsants. Fits stopped completely in 27 patients (43%) and 14 (22%) showed a reduction of attacks by more than 50%. The best results were in patients with absences (typical and atypical) associated with spike and wave discharges on the electroencephalogram. Myoclonic epilepsies responded well and improvement occurred with tonic-clonic seizures and focal motor fits. There was little or no improvement in temporal lobe epilepsy. Sodium valproate given alone did not cause unwanted effects but it potentiated many other anticonvulsants. An unusual side effect was temporary hair loss. A number of patients became more alert, school performances improved, and the management of subnormal patients became easier. PMID- 4209502 TI - Influence of local hydrophobic environment on acid dissociation constants of coordinated water molecules. PMID- 4209503 TI - Immune damage to liposomes containing lipids from Schistosoma mansoni worms. PMID- 4209504 TI - Mutagenicity testing of cyclamate and some pesticides in Drosophila melanogaster. PMID- 4209505 TI - Measurement of posture in japanese monkey (Macaca fuscata) by telemetry. PMID- 4209507 TI - Malignant external otitis and facial paralysis. PMID- 4209506 TI - Comparative characterization of microbiological and biological assays of protein quality of some foodstuffs. PMID- 4209508 TI - Amylase content of mixed saliva in children. PMID- 4209509 TI - Animal atmospheric exposure chamber system using a modified tank respirator. PMID- 4209510 TI - Serum IgE levels in individuals infected with Schistosoma mansoni and Schistosoma haematobium. PMID- 4209512 TI - The IUD and prostaglandins: a review of the evidence. PMID- 4209511 TI - Gonorrhea. PMID- 4209513 TI - Microbial production of cobalamin (vitamin B 12). PMID- 4209514 TI - [Experimental data on the action of ultrasonics on the vestibular portion of the labyrinth]. PMID- 4209515 TI - Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. AB - Various species of Streptomyces possess aminoglycoside-modifying enzymes. Streptomyces kanamyceticus contains an enzyme that acetylates the 6'-amino group of kanamycin A and B, gentamicin C(1a), and neomycin. Streptomyces spectabilis produces an enzyme that acetylates the 2'-amino group of the hexose ring of gentamicin C(1a). These enzymes catalyze reactions identical to those catalyzed by enzymes found in gram-negative bacteria containing R(antibiotic resistance) factors. The discovery of these enzymes suggests the possibility of an evolutionary relationship between the aminoglycosideinactivating enzymes (produced by resistance determinants) in bacteria containing R-factors and similar enzymes found in the actinomycetes. PMID- 4209517 TI - The etiology and implications of lactose intolerance. PMID- 4209516 TI - Methyldopa: physicochemical characterization of the erythrocyte autoantibody. PMID- 4209518 TI - An inhibitory effect of tolbutamide and glibenclamide (glyburide) on the pancreatic islets of normal animals. PMID- 4209519 TI - [Male urethritis at Dakar (epidemiological and biological aspects)]. PMID- 4209520 TI - Physical compatibility and chemical stability of cephapirin sodium in combination with non-antibiotic drugs in large-volume parenteral solutions. II. PMID- 4209521 TI - Galvanic skin responses (GSR) and plethysmographic changes induced by chlorimipramine, imipramine and placebo. PMID- 4209523 TI - The ultrastructure of the rat renal medulla as observed after improved fixation methods. PMID- 4209522 TI - Activity of BB-K8 (amikacin) against clinical isolates resistant to one or more aminoglycoside antibiotics. AB - One hundred fifty-two bacterial strains that possess resistance to kanamycin A, gentamicin, or tobramycin, or to more than one of these antibiotics, were collected from various sources in Canada, Europe, Japan, and the United States. This collection was composed of Staphylococcus aureus and Pseudomonas aeruginosa and members of the Enterobacteriaceae family. Their susceptibility to BB-K8 (amikacin), a new broad-spectrum semisynthetic derivative of kanamycin A, and to the other agents, was determined on Mueller-Hinton Medium by the twofold agar dilution method. Test results revealed that 60.5% of the isolates were resistant to 8 mug of tobramycin per ml, 67.1% to 8 mug of gentamicin per ml, 86.2% to 20 mug of kanamycin A per ml, and only 8.6% to 20 mug of amikacin per ml. Of interest is the fact that the amikacin-resistant strains were generally resistant to all of the other aminoglycosides. The broad spectrum of amikacin was not totally unexpected, because the compound has been shown to be a poor substrate for most enzymes that inactivate other aminoglycosides through O-phosphorylation, O-adenylylation, or N-acetylation. A number of susceptibility profiles were obtained when the organisms were tested against a series of nine aminoglycosides. The majority of these profiles resembled those found for organisms that possess known mechanisms of enzymatic inactivation. PMID- 4209524 TI - Editorial: Familial medullary carcinoma of the thyroid. PMID- 4209525 TI - Biliary magnesium loss in the postoperative patient. PMID- 4209526 TI - [Significance of HL-A leukocyte antigens in the serologic paternity determination]. PMID- 4209527 TI - [Management of a first attack of generalized epilepsy]. PMID- 4209528 TI - Cell death and autonomous gene action in lethals affecting imaginal discs in Drosophila melanogaster. PMID- 4209529 TI - Biological properties of macarbomycin, an antibiotic containing phosphorus. PMID- 4209530 TI - Letter: Four minor antibiotics from macarbomycins. PMID- 4209531 TI - EM49, a new peptide antibiotic. I. Fermentation, isolation, and preliminary characterization. PMID- 4209532 TI - [Temperature-induced conformational transition in the complex acriflavine phosphotungstic acid-200A deoxyribonucleoprotein]. PMID- 4209533 TI - Letter: Synthesis of (S)-4-amino-2-hydroxybutyryl derivatives of 3',4' dideoxykanamycin B and their antibacterial activities. PMID- 4209534 TI - Two types of melanogenesis in monolayer cultures of melanoma cells. PMID- 4209535 TI - Sarcoidal reactions in animals intensively immunized with tetanus vaccine. PMID- 4209536 TI - Effects of 2,4-dinitrophenol and dinactin on heat-sensitive and ecdysone-specific puffs of Drosophila salivary gland chromosomes in vitro. PMID- 4209539 TI - [Mechanical nutritional care]. PMID- 4209538 TI - Antigenic differences between normal mouse epidermis and methylcholanthrene induced squamous-cell carcinomas. PMID- 4209540 TI - [Fine structure of cyst and cyst wall of Sarcocystis tenella, Besnoitia jellisoni, Frenkelia sp. and Toxoplasma gondii]. PMID- 4209537 TI - [The postoperative course and results after total heart replacement by a blood pump (author's transl)]. PMID- 4209541 TI - [Waldenstrom's disease or collagenosis? Diagnostic problems with a patient]. PMID- 4209542 TI - [Attempt at the recovery of swine herds contaminated with Aujeszky's disease]. PMID- 4209543 TI - Long-term management of airway secretions and bronchospasm in chronic obstructive lung disease. PMID- 4209544 TI - Transient peripheral plasmacytosis. PMID- 4209545 TI - Early appearance and regional differences in intraneuronal and extraneuronal lipofuscin accumulation with age in the brain of a nonhuman primate (Macaca mulatta). PMID- 4209546 TI - Bone mineral content of the femoral neck after irradiation. PMID- 4209547 TI - Isolation and in vitro cultivation of the mammalian microsporidian Encephalitozoon cuniculi. PMID- 4209548 TI - Evaluation of bladder diverticulum using fiberoptic bronchoscope. PMID- 4209551 TI - [Glioneuronic macromolecular transport by formation of double-membraned vesicles]. PMID- 4209549 TI - Properties and function of the pyruvate: ferredoxin oxidoreductase from the blue green alga Anabaena cylindrica. PMID- 4209550 TI - Problems in the extraction DNA when utilizing pancreatic RNAase and pronase. PMID- 4209552 TI - [Variations of 17 beta-estradiol concentration in peripheral sheep blood in the course of the estrus cycle]. PMID- 4209553 TI - [Attempt at identification of antagonist agents produced by strains of serotype 1 Shigella dysenteriae]. PMID- 4209554 TI - The effects of protein synthesis-inhibiting antibiotics on the puffing pattern of Drosophila salivary gland chromosomes in vitro. PMID- 4209555 TI - Population mean marrow dose and leukaemia significant dose from beam-therapy in Japan, 1971. PMID- 4209556 TI - The anatomical basis of prosopagnosia. AB - Evidence is presented that patients with prosopagnosia have right anterior inferior occipital lesions in the region of the occipital temporal junction. Many if not all cases have an additional lesion in the left hemisphere; this is often but apparently not always symmetrical with the right hemisphere lesion. This evidence is discussed in relation to the anatomical connections of these regions and the results of experiments in animals. PMID- 4209557 TI - Isozymes of lysozyme in leukocytes and egg white: evidence for the species specific control of egg-white lysozyme synthesis. AB - Two structurally distinct forms of eggwhite lysozyme (EC 3.2.1.17) are known. The egg white of some species contains both of these forms, while the egg white of other species appears to contain only one or the other of them. We have immunological and electrophoretic evidence that the chicken, which has only one lysozyme type in its egg white, contains both types in its polymorphonuclear leukocytes. Experiments on Embden goose bone marrow showed that this tissue also contains both lysozymes, even though the egg white of this species contains only one of them. Our studies suggest that many avian species have the genetic loci that code for both forms of lysozyme, but that a species-specific regulatory mechanism controls whether one or the other or both of them are expressed during egg white production. The fact that two distinct lysozymes are present in chicken leukocytes may be of significance to the antibacterial mechanism of these cells, especially in light of the fact that they lack myeloperoxidase, an important leukocyte enzyme in mammals. PMID- 4209559 TI - [2d generation hypoglycemic coma due to sulfanylureas]. PMID- 4209558 TI - The activity-related ionization in carbonic anhydrase. AB - The catalytic activity of carbonic anhydrase (EC 4.2.1.1) is linked to the ionization of a group in close proximity to the essential zinc ion. Studies have been undertaken to delineate the ionizations germane to the active-site chelate system. Several imidazole ligand systems were studied in order to approach a representative chelate. The simplest involved the complexation of Zn(II) by imidazole and by N-methylimidazole. As well, two bidentate systems, Zn(II)-4,4' bis-imidazoylmethane and Co(II)-cyclic-L-histidyl-L-histidine were investigated. It was found that in a species containing metal-bound water and imidazole coordinated by means of the pyridinium nitrogen, the most acidic group was the pyrrole N-H in the imidazole ring. By the use of N-methylimidazole, the pK(a) of a metal-bound water molecule in a tri-imidazole ligand field was found to be 9.1. Noting the preference for labilization of the pyrrole hydrogen, the catalytic features of carbonic anhydrase are reexamined assuming that the pK(enz) is associated with the N-H ionization, and not with the ionization of metal-bound water. PMID- 4209560 TI - [Pathogenesis of experimental pulmonary tularemia in non-immunized and immunized animals]. PMID- 4209561 TI - [How to plan, administer and run health care (services) in the best way?]. PMID- 4209562 TI - [Salpingitic risk in gynecologic maneuvers and explorations]. PMID- 4209564 TI - [Hyperglycemic diabetic coma due to hyperosmolarity and without acido-ketosis]. PMID- 4209563 TI - Viral infections of the fetus. PMID- 4209565 TI - [Penicillamine D therapy of hyperbilirubinemia in newborn infants. Preliminary report]. PMID- 4209566 TI - An introduction to principles of veterinary clinical pharmacology: the elimination of drugs. 1. Rate of drug elimination. PMID- 4209567 TI - Serum and cerebrospinal fluid magnesium and calcium contents in idiopathic grandmal epilepsy. PMID- 4209568 TI - [Immunological studies in patients with lymphoma. 8. Detection of Australia antigen]. PMID- 4209569 TI - [Direct positive Coombs test for Rh isoimmunization]. PMID- 4209570 TI - [Blood cultures. Findings, methods and interpretation]. PMID- 4209571 TI - Manifestations of copper deficiency in a patient with systemic sclerosis on intravenous hyperalimentation. PMID- 4209572 TI - Blood viscosity in Waldenstrom's macroglobulinemia. PMID- 4209573 TI - Biochemical and genetic studies in two families with Fabry disease. PMID- 4209575 TI - Renal tubular antigen excretion in normal human urine. I. Immunochemical indentification. PMID- 4209574 TI - Scanning electron microscopy in the ultrastructural analysis of the mammalian cerebral ventricular system. PMID- 4209576 TI - [Autoantibodies against joint and prostatic antigen in spondylarthritis ankylopoetica]. PMID- 4209577 TI - Reversible, thermotropic alteration of nuclear membrane stucture and nucleocytoplasmic RNA transport in Tetrahymena. AB - We examine the effect of cooling upon the freeze-etch ultrastructure of nuclear membranes, as well as upon nucleocytoplasmic RNA transport in the unicellular eukaryote Tetrahymena pyriformis. Chilling produces smooth, particle-free areas on both faces of the two freeze-fractured macronuclear membranes. Upon return to optimum growth temperature the membrane-associated particles revert to their normal uniform distribution and the smooth areas disappear. Chilling lowers the incorporation of [(14)C]uridine into whole cells and their cytoplasmic RNA. Cooling from the optimum growth temperature of 28 degrees to 18 degrees C (or above) decreases [(14)C]uridine incorporation into cells more than into their cytoplasmic RNA; chilling to below 18 degrees C but above 10 degrees C causes the reverse. [(14)C]Uridine incorporation into whole cells and their cytoplasmic RNA reflects overall RNA synthesis and nucleocytoplasmic RNA transport, respectively. RNA transport decreases strongly between 20 degrees and 16 degrees C, which is also the temperature range where morphologically detectable nuclear membrane transitions occur. This suggests that the nuclear envelope limits the rate of nucleocytoplasmic RNA transport at low temperatures. We hypothesize that a thermotropic lipid phase transition switches nuclear pore complexes from an "open" to a "closed" state with respect to nucleocytoplasmic RNA transport. PMID- 4209578 TI - Selective release of content from microsomal vesicles without membrane disassembly. II. Electrophoretic and immunological characterization of microsomal subfractions. AB - Rough and smooth microsomes were shown to have similar sets of polypeptide chains except for the proteins of ribosomes bound to the rough endoplasmic reticulum (ER). More than 50 species of polypeptides were detected by acrylamide gel electrophoresis, ranging in molecular weight from 10,000 to approximately 200,000 daltons. The content of rough and smooth microsomes was separated from the membrane vesicles using sublytic concentrations of detergents and differential centrifugation. A specific subset of proteins which consisted of approximately 25 polypeptides was characteristic of the microsomal content. Some of these proteins showed high rates of in vivo incorporation of radioactive leucine or glucosamine, but several others incorporated only low levels of radioactivity within short labeling intervals and appeared to be long-term residents of the lumen of the ER. Seven polypeptides in the content subfractions, including serum albumin, contained almost 50% of the leucine radioactivity incorporated during 5 min and cross-reacted with antiserum against rat serum. Almost all microsomal glycoproteins were at least partly released with the microsomal content. Smooth microsomes contained higher levels of albumin than rough microsomes, but after short times of labeling with [(3)H]leucine the specific activity of albumin in the latter was higher, supporting the notion that newly synthesized serum proteins are transferred from rough to smooth portions of the ER. On the other hand, after labeling for 30 min with [(3)H]glucosamine, smooth microsomes contained higher levels of radioactivity than rough microsomes. This would be expected if glycosidation of newly synthesized polypeptides proceeds during their transit through ER cisternae. The labeling pattern of membrane proteins in microsomes obtained from animals which received three daily injections of [(3)H]leucine, the last administered 1 day before sacrifice, followed the intensity of bands stained with Coomassie blue, with a main radioactive peak corresponding to cytochrome P 450. After the long-term labeling procedure most content proteins had low levels of radioactivity; this was especially true of serum proteins which were highly labeled after 30 min. PMID- 4209580 TI - New attachment after treatment of intrabony defects in monkeys. PMID- 4209579 TI - Antibody-mediated effects on the periodontium. PMID- 4209581 TI - Osseous grafts and implants in the restoration of large oral defects. PMID- 4209582 TI - Amine functions of reduced basicity. Hypoglycemic and natriuretic alpha alkoxybenzylamidoximes, amidines, and cycloamidines. PMID- 4209583 TI - In vitro and in vivo activity of certain thiosemicarbazones against Trypanosoma cruzi. PMID- 4209585 TI - Nature of residual erythrocyte catalase activity in Swiss-type acatalasemia. PMID- 4209584 TI - Comparison of culture-induced, phenobarbital-induced and naturally-developing UDP glucuronyltransferase. PMID- 4209586 TI - [Anatomy of the 4th bundle of the fornix column]. PMID- 4209587 TI - Migration of mast cells through the area postrema. PMID- 4209588 TI - A rapid technique for separation of thymocytes from suspensions by centrifugation through silicone oil. PMID- 4209589 TI - Electron microscopic autoradiographic study of cholesteral passage across arterial and capillary endothelium. PMID- 4209590 TI - Transfer of heme from ferrihemoglobin and ferrihemoglobin isolated chains to hemopexin. PMID- 4209591 TI - A woman with multiple congenital anomalies, mental retardation and mosaicism for an unusual translocation chromosome t(6;19). PMID- 4209592 TI - Partial trisomy 13 in a case of Cyclopia with 13-14 translocation. PMID- 4209593 TI - [Parenteral nutrition in otolaryngology indication and limitations (author's transl)]. PMID- 4209594 TI - [Neurotoxic side effects of piperazine in adults. Epileptic twilight state with myoclonia (author's transl)]. PMID- 4209595 TI - Factors involved in the production of amblyopia. PMID- 4209596 TI - Ruptured cervical aneurysm with neurofibromatosis. PMID- 4209598 TI - The distribution and density of reduced cerebral blood flow following acute middle cerebral artery occlusion: an experimental study by the technique of hydrogen clearance in baboons. PMID- 4209597 TI - Segmental middle cerebral artery occlusion in primates: an experimental method requiring minimal surgery and anesthesia. PMID- 4209599 TI - Cutis verticis gyrata and the Lennox syndrome. PMID- 4209600 TI - Cerebral degenerative disorders of infancy and childhood. PMID- 4209601 TI - Endogenous glyceride synthesis rate in baboons fed diets containing sucrose or glucose. PMID- 4209602 TI - Lymphoma in owl monkeys (Aotus trivirgatus) inoculated with Herpesvirus saimiri: clinical, hematologic and pathologic findings. PMID- 4209603 TI - Recognition impaired and association intact in the memory of monkeys after transection of the fornix. PMID- 4209604 TI - A non-modality specific impairment in spatial learning after fornix lesions in monkeys. PMID- 4209605 TI - Specialization of the left hemisphere in baboon-evidence from directional preferences. PMID- 4209607 TI - [Acute loss of hearing. What can be done and expected? (author's transl)]. PMID- 4209608 TI - [The treatment of Meniere's disease (author's transl)]. PMID- 4209606 TI - [Rhinoplasty and nasal function (author's transl)]. PMID- 4209609 TI - [Hoarseness. Causes, diagnosis, treatment (author's transl)]. PMID- 4209610 TI - [Reconstructive possibilities in laryngo-tracheal stenoses (author's transl)]. PMID- 4209611 TI - [Improvement of the glutaraldehyde-OsO4 fixation of yeasts by pretreatment with formaldehyde and enzymatic degradation of the cell wall]. PMID- 4209612 TI - [Amputation and prothesis application. Comments on early and too early application]. PMID- 4209613 TI - [Angiography, scintigraphy and thermography in tumors of bone (author's transl)]. PMID- 4209614 TI - [Traumatic hip dislocation in childhood. Compiled statistics of the last 15 years and 4 own observations]. PMID- 4209615 TI - [Thanatophore dwarfism (author's transl)]. PMID- 4209616 TI - [Arteriovenous fistula. Therapy and experimental findings]. PMID- 4209617 TI - [Exclusively parenteral feeding of premature and young babies (author's transl)]. PMID- 4209618 TI - [Epidemiology of purulent meningitis seen in the pediatric department of Graz University between 1946 and 1971 (author's transl)]. PMID- 4209619 TI - The amino acid sequence of streptomyces griseus trypsin. II; The tryptic peptides. PMID- 4209620 TI - [Electrical activity and transmembranal ionic currents of the monkey myocardial fiber (Cercopithecidae family)]. PMID- 4209621 TI - Animal DNA-dependent RNA polymerases. Molecular structures and immunological properties of calf-thymus enzyme AI and of calf-thymus and rat-liver enzymes B. PMID- 4209622 TI - An immunological investigation of the structure and function of ribulose 1,5 bisphosphate carboxylase. PMID- 4209623 TI - Isolation of carbonic anhydrase from dog erythrocytes and determination of its N terminal amino-acid sequence. PMID- 4209625 TI - Editorial: Diabetes in the young. PMID- 4209624 TI - [Evaluation of left ventricular function in coronary disease. Considerations in favor of a more rational approach]. PMID- 4209626 TI - Recent advances in surgery of the brain. Dr. P. Kutumbiah endowment lecture- 1971. PMID- 4209628 TI - Use of parenteral hyperalimentation in treatment of alkaline reflux gastritis. PMID- 4209627 TI - Place of the anesthetist in the intensive care unit. PMID- 4209629 TI - Coccidia of the cotton rat, Sigmodon hispidus, from Alabama. PMID- 4209630 TI - Mandibular joint involvement in a case of Fanconi's syndrome with renal failure. PMID- 4209631 TI - Coeliac disease. Barium studies. PMID- 4209632 TI - The blockade of the local generation of prostaglandins explains the analgesic action of aspirin. PMID- 4209633 TI - [Isolation and characterization of the immunizing agent of crystal violet vaccines against hog cholera]. PMID- 4209634 TI - Unusual spondyloepiphyseal and spondylometaphyseal dysplasias of childhood. PMID- 4209635 TI - [Differential diagnosis of hypertensive findings in infancy (author's transl)]. PMID- 4209636 TI - [The diagnosis and operative treatment of massive intracerebral hemorrhage (author's transl)]. PMID- 4209637 TI - [Occupation medicine-results of a routine examination (author's transl)]. PMID- 4209638 TI - The clinical usefulness of C-reactive protein (CRP) determinations in bacterial meningitis and septicemia in infancy. PMID- 4209639 TI - [PCB]. PMID- 4209640 TI - Transferable resistance to carbenicillin and gentamicin in Pseudomonas aeruginosa. PMID- 4209641 TI - A carbenicillin R factor from Pseudomonas aeruginosa. PMID- 4209642 TI - Detection of biological false positive syphilis serum reactions. PMID- 4209643 TI - Effects of puff-adder venom on coagulation, fibrinolysis and platelet aggregation in the baboon. PMID- 4209644 TI - Combined action of sulbenicillin and gentamicin. PMID- 4209645 TI - Pediatric surgery. Current concepts. PMID- 4209646 TI - Epiphyseal injuries. PMID- 4209648 TI - Normal serum triiodothyronine concentration and the lack of TSH response to TRH in patients with euthyroid Graves' disease. PMID- 4209647 TI - The child who convulses with fever. PMID- 4209649 TI - Fluorescein angiography of the glaucomatous disc. PMID- 4209650 TI - Kuru and Creutzfeldt-Jakob disease. Experimental models of noninflammatory degenerative slow virus disease of the central nervous system. PMID- 4209651 TI - Viral and non-viral properties of the scrapie agent. PMID- 4209652 TI - Enhancement of baboon liver allografts with noncytotoxic preparations of alloimmune IgG. PMID- 4209653 TI - Antimacaque thymocyte globulins. Toxicity and immunodepressive effect in the human species. PMID- 4209654 TI - [Production of anti-RhD immunoglobulin]. PMID- 4209655 TI - [Is surgical treatment necessary for lesions of the medial collateral ligament of the ankle?]. PMID- 4209656 TI - [Meningitis due to Listeria monocytogenes. Presentation of a case and literature review]. PMID- 4209658 TI - [Operative treatment of diverticulitis of the large intestine (author's transl]. PMID- 4209657 TI - Genetic transformation of the blue-green bacterium, Anacystis nidulans. PMID- 4209659 TI - [Treatment of postoperative edema with Reparil. Report of experiences (author's transl)]. PMID- 4209660 TI - Human antibody response to group A streptococcal teichoic acid. PMID- 4209661 TI - Food preservation and antibacterial properties of four fluoroalkane compounds. PMID- 4209662 TI - Prolactin and thyrotropin in thyroid diseases: lack of evidence for a physiological role of thyrotropin-releasing hormone in the regulation of prolactin secretion. PMID- 4209663 TI - Vertebral epidermal transamidases. PMID- 4209664 TI - Relative rates of transcapillary movement of free thyroxine, protein-bound thyroxine, thyroxine-binding proteins, and albumin. AB - The rate of appearance of labeled thyroxine (T4) and albumin in lymph from various areas after simultaneous i.v. injection of the labeled substances in conscious ambulatory sheep has been used to estimate the relative rates of transcapillary movement of stable T4 and albumin. Labeled T4 appeared in hepatic lymph at the same rate as albumin. In intestinal and leg lymph, labeled T4 appeared eight and four times as rapidly as albumin indicating that T4 crosses capillaries in these areas independently of and much more rapidly than albumin and other proteins having similar distribution kinetics. The lymph:plasma ratios for all the T4-binding proteins including albumin were very similar in any one area showing that the relative fractional rates of transcapillary movement of these proteins were very similar. Therefore in extrahepatic areas, transcapillary movement of T4 in the protein-bound form was quantitatively much less important than in the free form. The findings support earlier views, recently questioned, that free T4 is of considerable physiological significance. PMID- 4209665 TI - [Influencing of endochondral ossification by thyro-parathyroidectomy and concurrent vitamin D deficiency]. PMID- 4209666 TI - Poly-DL-alanyl skin isograft rejection by purified anti-poly-DL-alanyl antibodies. PMID- 4209667 TI - Interaction between an R factor and an element conferring resistance to mercuric ions in Pseudomonas aeruginosa. PMID- 4209669 TI - X-ray induced mitotic recombination in Drosophila melanogaster. 3. Dose dependence of the "pairing" component. PMID- 4209668 TI - Direct assay for sigma factor activity and demonstration of the loss of this activity during sporulation in Bacillus subtilis. PMID- 4209670 TI - The ribosomal proteins of Drosophila melanogaster. 3. Further studies on the ribosomal protein composition during development. PMID- 4209672 TI - [Rare complications after insertion of a vena cava catheter via the subclavian vein (author's transl)]. PMID- 4209671 TI - Phenotypic properties of Bacillus subtilis mutants defective in recombination and repair functions. PMID- 4209673 TI - [Differential diagnosis of disturbances of consciousness (author's transl)]. PMID- 4209674 TI - [Why does iron deficiency still occur in pregnancy? (author's transl)]. PMID- 4209675 TI - [The effect of ascorbic acid on the absorption of sodium ferricitrate complex (author's transl)]. PMID- 4209676 TI - [Reinterventions in biliary surgery]. PMID- 4209677 TI - [A new method for treatment of extreme obesity]. PMID- 4209678 TI - Actions of chinoform and oxine on the isolated phrenic nerve-diaphragm preparation of the rat: the accumulation of chinoform by rat diaphragm strip. PMID- 4209679 TI - [Influence of 2-mercaptoethanol and D-penicillamine on the radial immunodiffusion]. PMID- 4209681 TI - Interferon production by simian lymphoblastoid cell lines. PMID- 4209680 TI - A "double-blind" trial of disodium cromoglycate in Thai asthmatic children. PMID- 4209682 TI - Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates. PMID- 4209683 TI - The induction of a fatal desmoplastic mesothelial reaction in rabbits with mouse Ehrlich ascites carcinomata. PMID- 4209684 TI - Induction of autoallergic gastritis in dogs. PMID- 4209685 TI - Clinical and hormonal response to bromocriptin (CB-154) in the galactorrhea syndromes. PMID- 4209686 TI - Growth hormone in adults with protein-calorie malnutrition. PMID- 4209687 TI - Immunochemical quantitation of human transcortin. PMID- 4209688 TI - Thyroxine-binding globulin in infant protein-calorie malnutrition. PMID- 4209689 TI - Nanophyetus salmincola infections in kippered salmon. PMID- 4209690 TI - Carcinoma of the cervix: establishment of a hyperbaric oxygen trial associated with the use of the cathetron. PMID- 4209691 TI - Nitroglycerin to unmask reversible asynergy. Correlation with post coronary bypass ventriculography. PMID- 4209692 TI - The development of the macronucleus in the ciliated protozoan Stylonychia mytilus. PMID- 4209694 TI - Computerized intravenous glybenclamide test in early diagnosis of diabetes mellitus. PMID- 4209693 TI - In vitro secretion of insulin after glucose, sulphonylureas, adrenergic and cholinergic substances studied by isolated perfused rat pancreas. PMID- 4209695 TI - Letter: Development of gelatin-urease films. PMID- 4209696 TI - Simplified water-loading test in bacteriuria. PMID- 4209697 TI - [Problems in diagnosis and therapy of digestive hemorrhages in infancy]. PMID- 4209698 TI - [First aid and treatment of massive hemorrhages from the gastrointestinal tract]. PMID- 4209699 TI - [Anesthesiological problems and postoperative treatment in urgent interventions for severe hemorrhages of the gastrointestinal tract]. PMID- 4209700 TI - [Massive digestive hemorrhages in the pediatric age]. PMID- 4209701 TI - Response of units in striate cortex of squirrel monkeys to visual and electrical stimuli. PMID- 4209702 TI - Effects of dentate cooling on rapid alternating arm movements. PMID- 4209703 TI - [Sex chromatin in immunogenetic conflict]. PMID- 4209705 TI - Effect of exogenous estradiol-17 beta on vitellogenic oocyte growth in ovaries of the toad Bufo bufo bufo (L.) during the postspawning period. PMID- 4209704 TI - Cross-reactivity of monkey pituitary extracts in human radioimmunoassays. PMID- 4209706 TI - Variations in plasma amino acid concentrations after abdominal surgical procedures. PMID- 4209707 TI - Investigations on some physico-chemical and immunological properties of viral hepatitis antigen (HB Ag). PMID- 4209709 TI - Intra-abdominal vascular complications of diabetic ketosis. PMID- 4209708 TI - Brain growth in children with marasmus. A study using head circumference measurement, transillumination and ultrasonic echo ventriculography. PMID- 4209710 TI - Carcino--embryonic antigen and its significance. PMID- 4209711 TI - [Lyophilized suspension of Lactobacillus acidophilus in supportive treatment of mycotic forms of vaginitis in women]. PMID- 4209712 TI - [Detection of fetal red blood cells in maternal blood stream in cases of anti-D immunoglobulin administration]. PMID- 4209713 TI - [Determination of alpha-1 fetoprotein in amniotic fluid during the 1st trimester of pregnancy]. PMID- 4209714 TI - Factors affecting fluid movement and intercellular space formation in the toad bladder. PMID- 4209715 TI - Effect of palatoplasty and cleft extent on facial and dental relations. PMID- 4209716 TI - Inhibition of inter-microbial predation by chlorinated hydrocarbons. PMID- 4209717 TI - Effect of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid on glutamate uptake by synaptosomes. PMID- 4209718 TI - Coronary bypass grafts. PMID- 4209719 TI - Endarterectomy in surgical treatment of coronary disease. PMID- 4209720 TI - Eradication of carriage of Neisseria meningitidis in families: a study in Brazil. PMID- 4209721 TI - The human fallopian tube: a laboratory model for gonococcal infection. PMID- 4209723 TI - Comparison of three agents of acute infectious nonbacterial gastroenteritis by cross-challenge in volunteers. PMID- 4209722 TI - Gas chromatography as a potential means of diagnosing arthritis. I. Differentiation between staphylococcal, streptococcal, gonococcal, and traumatic arthritis. PMID- 4209724 TI - Transmission of rat virus in milk of rats. PMID- 4209725 TI - Studies with (plus)--octanoylcarnitine in experimental diabetic ketoacidosis. PMID- 4209726 TI - Absorption of amino acids in malnourished rats. PMID- 4209727 TI - Hypergraphia in temporal lobe epilepsy. PMID- 4209728 TI - Furosemide and pentobarbital in cryogenic cerebral injury and edema. PMID- 4209729 TI - Intraluminal duodenal diverticulum. A rare cause of acute pancreatitis. PMID- 4209730 TI - Fusion of the scoliotic spine in young children. PMID- 4209732 TI - Mitosis-like macronuclear division in a ciliate. PMID- 4209731 TI - The role of genetic balance in control of transcription rate in the X-chromosomes of Drosophila melanogaster. PMID- 4209735 TI - [Certain socioeconomic aspects of injuries in agriculture]. PMID- 4209734 TI - Leukocyte antigens of primates. PMID- 4209736 TI - Children with protein-calorie malnutrition evacuated to Gabon during the Nigerian civil war. PMID- 4209733 TI - The histones of the ciliated protozoan Stylonychia mytilus. PMID- 4209737 TI - Depression of immunity in protein-calorie malnutrition: a post-mortem study. PMID- 4209738 TI - Teaching better nutrition by domiciliary management of cases of protein calorie malnutrition in rural areas (a longitudinal study of clinical and economical aspects). PMID- 4209740 TI - The EEC syndrome. PMID- 4209739 TI - Lead poisoning. Current status of the problem facing pediatricians. PMID- 4209741 TI - Spin-lattice relaxation times of imidazole protons and their relevance to NMR studies of proteins. PMID- 4209743 TI - Letter: Random deviations or asynchronous DNA synthesis? PMID- 4209742 TI - Reduced susceptibility to scrapie in mice after steroid administration. PMID- 4209744 TI - Dominance and sexual behavior: a hypothesis. PMID- 4209745 TI - The action of protein synthesis inhibitors and thyrotropin releasing factor on the ultrastructure of rat thyrotrophs. PMID- 4209746 TI - Accurate office diagnosis of vaginitis. PMID- 4209747 TI - Ultrastructural changes in the bacterial vegetative endocarditis. PMID- 4209748 TI - Proceedings: Overview of the mammary gland. PMID- 4209749 TI - Proceedings: The mammary glands of rhesus monkeys. PMID- 4209751 TI - Recovery of Neisseria meningitidis from the nasopharynx. Comparison of two techniques. PMID- 4209750 TI - Proceedings: Neuroendocrinology of lactation. PMID- 4209752 TI - Oculodentodigital dysplasia. Picture of the month. PMID- 4209753 TI - Diphenylhydantoin--induced hepatic necrosis. PMID- 4209754 TI - Quantitative scintigraphic method of estimating the circulation of cerebrospinal fluid. PMID- 4209756 TI - Unit activity in accessory optic system in alert monkeys. PMID- 4209755 TI - Cerebellopontine cisternography with a positive contrast medium. PMID- 4209757 TI - Dose distribution analysis of moving-strip technique for abdominal irradiation using 10 MV x rays. PMID- 4209758 TI - BB-K8: A new aminoglycoside for intravitreal injection in bacterial endophthalmitis. PMID- 4209759 TI - Letter: Norrie's disease. PMID- 4209760 TI - Arterial infusion of 5-fluorouracil as a treatment for carcinoma of the prostate. PMID- 4209761 TI - Enhancement and deactivation of some microsomal glycosyl transferases. PMID- 4209762 TI - Comparative responsiveness of euthyroid and hypothyroid rat pituitary tissue to thyrotropin releasing hormone in vitro. PMID- 4209763 TI - [Therapy of so-called vaginal recurrence of operated rectal carcinoma]. PMID- 4209764 TI - [Influence of x-rays on electrolyte shifts and myocardial metabolism. 3. Radiation-induced changes of magnesium concentration in isolated guinea pig atrium]. PMID- 4209765 TI - Purification and some serological properties of staphylococcal nuclease. PMID- 4209767 TI - Gonogrow, an improved, selective medium for the isolation of Neisseria gonorrhoeae. PMID- 4209766 TI - Passive electrical properties of toad urinary bladder epithelium. Intercellular electrical coupling and transepithelial cellular and shunt conductances. AB - The electrical resistances of the transcellular and paracellular pathways across the toad urinary bladder epithelium (a typical "tight" sodium-transporting epithelium) were determined by two independent sets of electrophysiological measurements: (a) the measurement of the total transepithelial resistance, the ratio of resistance of the apical to the basal cell membrane, and cable analysis of the voltage spread into the epithelium; (b) the measurement of the total transepithelial resistance and the ratio of resistances of both cell membranes before and after replacing all mucosal sodium with potassium (thus, increasing selectively the resistance of the apical membrane). The results obtained with both methods indicate the presence of a finite transepithelial shunt pathway, whose resistance is about 1.8 times the resistance of the transcellular pathway. Appropriate calculations show that the resistance of the shunt pathway is almost exclusively determined by the zonula occludens section of the limiting junctions. The mean resistance of the apical cell membrane is 1.7 times that of the basal cell membrane. The use of nonconducting materials on the mucosal side allowed us to demonstrate that apparently all epithelial cells are electrically coupled, with a mean space constant of 460 microm, and a voltage spread consistent with a thin sheet model. PMID- 4209769 TI - The use of sodium sulfite as a neutralizer for evaluating povidone-iodine preparations. PMID- 4209770 TI - Fracture of the talus. A study of its genesis and morphology based upon cases with associated ankle fracture. PMID- 4209768 TI - Evaluation of skin cleansing procedures using the wipe-rinse technique. PMID- 4209771 TI - Rupture of the posterior talotibial ligament with the avulsion of a bone fragment from the talus. PMID- 4209772 TI - Cardiohemodynamic effects of nitroglycerin and several vasodilators. PMID- 4209773 TI - Angina pectoris induced by intravenous administration of 50 per cent glucose. PMID- 4209774 TI - Thymineless death in Bacillus subtilis: correlation between cell lysis and deoxyribonucleic acid breakdown. AB - Bacillus subtilis carrying an inducible defective phage is several times more sensitive to thymineless death than a mutagenized derivative that behaves as a nonlysogen. When the integrity of the deoxyribonucleic acid (DNA) of both strains was examined during thymine starvation by transformation experiments, sedimentation studies, and measurements of acid-soluble DNA degradation products, it was shown that extensive DNA breakdown occurred only in the lysogenic strain. During thymine starvation of this strain, there is a progressive proclivity to lysis, followed by leakage of DNA and DNA degradation products. Such leakage was not observed in the nonlysogen. A correlation between proclivity to lysis and extensive DNA degradation is indicated. PMID- 4209775 TI - Sensitivity of an early step in the sporulation of Bacillus subtilis to selective inhibition by ethidium bromide. AB - When a final concentration of 0.4 mug of ethidium bromide (EB) per ml, which is subinhibitory to vegetative growth, is added to sporulating cells of Bacillus subtilis Marburg during either stage 0 or the early part of stage 1, morphogenesis is blocked. If the given concentration of EB is added after the early part of stage 1, sporogenesis is unaffected. The synthesis of the serine protease and antibiotic, which are believed to be associated with sporulation events during the early part of stage 0, are not inhibited by EB. Enhanced binding of [(14)C]benzylpenicillin to sporulating cells during septation (stage 2) is a measure of the presence of terminal enzymes for germ cell wall peptidoglycan synthesis. EB does not interfere with the binding of penicillin to sporulating cells, but penicillin remains more permanently bound to EB-treated postlogarithmic cells than to untreated sporulating cells. The absence of an interval of increased penicillin binding activity during stage 2 by sporulating cells treated with EB indicates that EB blocks sporulation prior to the completion of the germ cell wall. PMID- 4209776 TI - Adenine nucleotide changes associated with the initiation of sporulation in Bacillus subtilis. AB - At the end of the exponential growth phase of Bacillus subtilis, there is a decrease in the energy level of the cell, whether expressed as adenosine triphosphate concentration or adenylate energy charge. Phosphate limitation of exponentially growing cells produces a similar decrease in the energy level of the cell, and sporulation is derepressed in the presence of 10 mM glucose. A reduction in the tryptophan concentration of the medium during phosphate limitation of the tryptophan auxotroph B. subtilis 168 prevented the decrease in energy charge. Cells do not sporulate under these conditions. Energy charge values of 0.30 to 0.35 found during sporulation do not lead to cell death. PMID- 4209779 TI - Salivary Pseudomonas aeruginosa. PMID- 4209777 TI - Nitrogenase activity and photosynthesis in Plectonema boryanum. AB - Nitrogen-starved Plectonema boryanum 594 cultures flushed with N(2)/CO(2) or A/CO(2) (99.7%/0.3%, vol/vol) exhibited nitrogenase activity when assayed either by acetylene reduction or hydrogen evolution. Oxygen evolution activities and phycocyanin pigments decreased sharply before and during the development of nitrogenase activity, but recovered in the N(2)/CO(2) cultures after a period of active nitrogen fixation. Under high illumination, the onset of nitrogenase activity was delayed; however, the presence of 3-(3, 4-dichlorophenyl)-1, 1 dimethylurea (DCMU) eliminated this lag. Oxygen was a strong and irreversible inhibitor of nitrogenase activity at low (>0.5%) concentrations. In the dark, low oxygen tensions (0.5%) stimulated nitrogenase activity (up to 60% of that in the light), suggesting a limited but significant respiratory protection of nitrogenase at low oxygen tensions. DCMU was not a strong inhibitor of nitrogenase activity. A decrease in nitrogenase activity after a period of active nitrogen fixation was observed in the N(2)/CO(2-), but not in the A/CO(2-), flushed cultures. We suggest that this decrease in nitrogenase activity is due to exhaustion of stored substrate reserves as well as inhibition by the renewed oxygen evolution of the cultures. Repeated peaks of alternating nitrogenase activity and oxygen evolution were observed in some experiments. Our results indicate a temporal separation of these basically incompatible reactions in P. boryanum. PMID- 4209778 TI - Septum formation in Escherichia coli: characterization of septal structure and the effects of antibiotics on cell division. AB - Septa can be demonstrated in sections of Escherichia coli strains B and B/r after fixation with acrolein and glutaraldehyde. The septum consists of an ingrowth of the cytoplasmic membrane and the mucopeptide layer; the outer membrane is excluded from the septum until the cells begin to separate. Mesosomes have also been observed. The septum is highly labile and, except in the chain-forming strains, E. coli D22 env A and CRT 97, not easily preserved by standard procedures. The labile nature of the septum may be due to the presence of autolysin(s) located at the presumptive division site. Blocking division by addition of ampicillin (2 to 5 mug/ml) to cells of E. coli B/r produces a bulge at the middle of the cells; bulge formation is stopped by addition of chloramphenicol. Cephalosporins also induce bulge formation but may stop cell elongation as well as division. Bulge formation, due to the presumed action of an autolysin(s), may be an initial step in the septation sequence when the mucopeptide is modified to allow construction of the septum. In a nonseptate filament-forming strain, PAT 84, which ceases to divide at 42 C, bulge formation only occurs in the presence of ampicillin at the time of a shift-down at 30 C or at 42 C in the presence of NaCl (0.25 to 0.34 M). Experiments with chloramphenicol suggest that the filaments are fully compartmentalized but fail to divide owing to the inactivation, rather than loss of synthesis, of an autolysin at 42 C. PMID- 4209780 TI - Mechanism of inhibition of bacterial growth by adenine. PMID- 4209781 TI - Separation of transfer RNA's from Bacillus subtilis, Bacillus stearothermophilus and chicken liver by polyacrylamide gel electrophoresis. PMID- 4209782 TI - The stability of taka-amylase A immobilized on various sizes of matrix. PMID- 4209783 TI - Partial purification and some properties of cyclamate sulfamatase. PMID- 4209784 TI - Evidence for the role of disulfide bonds in the masking of chromophore groups in bovine kappa-casein. PMID- 4209785 TI - Recent advances in parenteral nutrition. PMID- 4209787 TI - Interspecific variability of red cell phosphoglycerate kinase in primates. PMID- 4209786 TI - [Effect of parenterally administered nutrients on the functions of gastrointestinal tract]. PMID- 4209788 TI - [3 new types of extrusive organoids in lower marine infusoria]. PMID- 4209789 TI - Clinical significance of native DNA antibodies in systemic lupus erythematosus and other connective tissue diseases. PMID- 4209790 TI - Hperglycaemic hyperosmolar non-ketotic metabolic decompensation in diabetes. PMID- 4209791 TI - [Prolonged action of high vacuum on microorganisms]. PMID- 4209792 TI - [Importance of the fluorescence of trypaflavine complexes with DNA in bacteria for their taxonomy]. PMID- 4209793 TI - [Lysis of Hydrogenomonas eutropha Z-1 cells by Micromonospora vulgaris PA II-4 enzymes]. PMID- 4209794 TI - [Temperate cyanophage A-4 (L) of the blue-green alga Anabaena variabilis]. PMID- 4209795 TI - [Intracellular development of Bacillus subtilis AR7 phage]. PMID- 4209796 TI - Induction of the L-phase of Listeria monocytogenes by rabbit alveolar macrophages in vitro. PMID- 4209798 TI - Aliphatic alcohols and bacterial motile behavior. PMID- 4209797 TI - The characterization of a Bacillus capable of blue-green bactericidal activity. PMID- 4209799 TI - [Information on the reticuloendotheliotropic vital dyes lithium carmine and trypan blue]. PMID- 4209800 TI - [Spectrophotometric studies on the light sensitivity of PMS in aqueous solution]. PMID- 4209801 TI - [Changes in nucleic acids after pretreatment for ultraviolet cytospectrophotometric determination]. PMID- 4209802 TI - [Chromatographic separation of products of PMS by photochemical reaction]. PMID- 4209803 TI - [Characterizing of the NADH2-lipoamide dehydrogenase as tetrazolium reductase (author's transl)]. PMID- 4209804 TI - Glycolipids of urinary tract transitional epithelium. PMID- 4209805 TI - [About the spectralphotometric analysis and the index of purification E235-E280 of glutaraldehyde (author's transl)]. PMID- 4209806 TI - [Toxicity studies as an aid in judging secondary effects in man]. PMID- 4209807 TI - [Glutaraldehyde]. PMID- 4209808 TI - [Cholecystectomy for cholecystoses. Late results (author's transl)]. PMID- 4209809 TI - [Prophylactic administration of Bactrim in chronic bronchitis. A double blind clinical and biological study (author's transl)]. PMID- 4209810 TI - [Organization of ambulatory treatment of pulmonary tuberculosis in Algeria]. PMID- 4209811 TI - [Pulmonary tuberculosis and general medicine. 15 years experience]. PMID- 4209812 TI - [Extra-respiratory tuberculosis]. PMID- 4209813 TI - Studies on the degradation of sym-homospermidine by Pseudomonas aeruginosa. PMID- 4209814 TI - Proceedings: Secretion of airway in anaphylactic shock and the effect of certain drugs. PMID- 4209816 TI - Contamination of cord blood with maternal blood during delivery. PMID- 4209815 TI - Secondary respiratory infection in hospital patients: effect of antimicrobial agents and environment. AB - A prospective study of 358 medical and 234 postoperative patients with clinical evidence of secondary chest infection showed that previous administration of antimicrobial agents greatly reduced the chance of obtaining a clear-cut laboratory report. In patients with radiographical evidence of pneumonia this led to a fourfold decrease in the overall rate of isolation of potential pathogens. Furthermore, 81 diverse "coliforms" were isolated from 258 medical and surgical patients who had received previous antimicrobial therapy while only four coliforms (all Escherichia coli) were isolated from 334 untreated patients. Thus the general hospital environment on its own seemed to have a negligible influence in promoting the growth of coliform flora in sputum. Any unique effect of underlying disease in this regard was masked by that of previous therapy. Finally, the results raised the possibility that previous antimicrobial therapy might have increased the risk of secondary pneumonia in hospital patients. PMID- 4209817 TI - Use of elemental diets to correct catabolic states prior to surgery. AB - An elemental diet was used to prepare 11 severely debilitated malnourished patients for operation. Indications included: 1) as a substitute for parenteral hyperalimentation when catheter sepsis occurred with the latter; 2) high small fistulae; 3) short bowel syndrome; 4) radiation enteritis; and 5) partial obstruction of the gastrointestinal tract. All patients were converted to a positive nitrogen balance as evidenced by a substantial gain in weight and in serum albumin levels. All tolerated corrective operations without difficulty and their wounds healed per primum. PMID- 4209818 TI - Serum antibody in patients with breast disease: Correlation with histopathology. AB - Antibody to a breast cancer antigen was detected by immunodiffusion or complement fixation in at least one serum sample in 46% of 84 patients with a diagnosis of carcinoma, 34% of 96 patients with fibrocystic disease and 25% of 44 patients with fibroadenoma. A single serum sample obtained from screenees of the Detection Center for Breast Diseases was tested by immunodiffusion only and antibody was found in 3 of 206 screenees (1.5%). Eleven of 13 patients with breast cancer metastatic to lymph nodes and no detectable serum antibody either had recurrence or were dead within 12 months of mastectomy. Fifteen of 18 patients with breast cancer metastatic to lymph nodes and with detectable serum antibody were alive and free of disease for up to 24 months. Histologic slides from patients with a diagnosis of fibrocystic disease or fibroadenoma were reviewed for the presence of ductal epithelial hyperplasia. Ductal epithelial hyperplasia was present in a similar per cent of patients with no detectable serum antibody as those with antibody detected in the serum. Severe sinus histiocytosis of the axillary lymph nodes was present in 45% of those cancer patients with serum antibody and only 11% of those cancer patients with no detectable serum antibody. PMID- 4209819 TI - [The effect of urea on the water reabsorption of the sodium concentrating kidney in the steady state (author's transl)]. PMID- 4209821 TI - Origin of cerebellar climbing fibers in the rhesus monkey. PMID- 4209820 TI - Unresponsiveness of exocrine rat pancreas to calcemic challenges (hypercalcemia, EDTA hypocalcemia or calcitonin administration) which influence stomach function. PMID- 4209822 TI - Evaluation of genetic structure of Drosophila melanogaster population with respect to the characteristic radius incompletus. Report II. Verification of Wright and Fisher systems. PMID- 4209823 TI - [Vegetable lipids. 6. Fatty acid composition of mono- and digalactolipids of mature beans, peas and soy beans]. PMID- 4209824 TI - [Course of typhoid and paratyphoid B during pregnancy and lactation]. PMID- 4209825 TI - The fine structure of cysts of Frenkelia (the M-organism). PMID- 4209826 TI - The age of Ixodes ricinus ticks as a factor of their susceptibility to pp-DDT, imidan and carbaryl. PMID- 4209827 TI - Inactivation of allantoinase of Pseudomonas aeruginosa in vivo. PMID- 4209828 TI - [The presence of malic enzyme and malo-lactic enzyme in various lactic acid bacteria (author's transl)]. PMID- 4209829 TI - [Afferent activity originating in the upper beak of the domestic chicken]. PMID- 4209830 TI - [Modifications of ovarian 17 beta estradiol in female rate treated by LH at the onset of 4 day cycles]. PMID- 4209831 TI - Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. II. The effects of inhibitors of protein synthesis. PMID- 4209832 TI - EM49, a new peptide antibiotic. 3. biological characterization in vitro and in vivo. PMID- 4209834 TI - Monolayer mass culture on disposable plastic spirals. PMID- 4209833 TI - [Letter: Chronic urticarian eruption, bone lesions and IgM macroglobulinemia equals Waldenstrom's disease]. PMID- 4209835 TI - Distribution and excretion of cyclocytidine in monkeys, dogs, and rats. PMID- 4209836 TI - Suppression of tumor growth and regression of established tumor with oil-attached mycobacterial fractions. PMID- 4209837 TI - DNA reassociation kinetics of closely related species. PMID- 4209838 TI - Intercellular adhesion: modification by dielectric properties of the medium. PMID- 4209839 TI - Changes in serum thyroxine-binding proteins in endemic goitre and endemic cretinism. PMID- 4209840 TI - A comparison of effective thyroxine ratio, free thyroxine index and free thyroxine concentration in correcting for thyroxine-binding abnormalities in serum. PMID- 4209841 TI - The clinical application of a new prosthetic arteriovenous shunt. Characteristics and advantages over the standard A-V shunt and the A-V fistula. PMID- 4209843 TI - Prevention of induced autophagy by emetine in exocrine cells of mouse pancreas and seminal vesicle. PMID- 4209842 TI - Isolation and partial characterization of the internal structural proteins from murine intracisternal A particles. PMID- 4209844 TI - Fine structural alterations in mesothelial cells associated with cardiac anomaly. PMID- 4209845 TI - Nuclear fibrous lamina in pathological human synovial membrane. PMID- 4209846 TI - [The cellular reaction in the spleen after traumatic liver injury of mice (author's transl)]. PMID- 4209847 TI - [Quantitative determination of glycoprotein fractions in the serum and plasma of patients with porphyria cutanea tarda]. PMID- 4209848 TI - The behavior of delta-aminolevulinic acid levels in the blood of patients on regular dialysis treatment (RDT). PMID- 4209849 TI - [Iron ions as an essential for the antigen-antibody reaction on the basement membrane in bullous pemphigoid (author's transl)]. PMID- 4209850 TI - On the effects of tricarboxylic acid cycle intermediates on sodium transport by the toad bladder. PMID- 4209852 TI - [Indirect hemagglutination test in the diagnosis of listerosis in sheep]. PMID- 4209851 TI - [Serum proteins in pigs]. PMID- 4209854 TI - [Ontogenetic changes in the protein spectrum of blood sera in lambs]. PMID- 4209853 TI - [Comparative study of antigen extracts from Ascaris suum, Ascaris ovis and Ascaris lumbricoides]. PMID- 4209856 TI - [Intal in the treatment of asthma]. PMID- 4209855 TI - [Edwards' syndrome and esophageal atresia]. PMID- 4209858 TI - [Intermittent chemotherapy of pulmonary tuberculosis (author's transl)]. PMID- 4209859 TI - [Industrial medicine and Chagas' disease]. PMID- 4209861 TI - Ketogenesis and the Indian diabetic. PMID- 4209860 TI - [Morphological properties of Rickettsia prowazekii cultivated for a long period in body lice]. PMID- 4209862 TI - Letter: Hyperamylasemia and diabetic ketoacidosis. PMID- 4209863 TI - Specific human antibodies to enterotoxins A, B, and C1 of Staphylococcus: their increased synthesis in staphylococcal infection. PMID- 4209864 TI - Relationship of delayed-type hypersensitivity and acquired cellular resistance in experimental airborne tuberculosis. PMID- 4209865 TI - Letter: Alcohol and the liver. PMID- 4209867 TI - Thrombin substrates and the proteolytic site of thrombin action on human-platelet plasma membranes. PMID- 4209866 TI - Multiple gene sites for 5S and 18 plus 28S RNA on chromosomes of Glyptotendipes barbipes (Staeger). AB - Ribosomal RNAs (28 + 18S and 5S) and 4S RNA extracted from the chironomid Glyptotendipes barbipes were iodinated in vitro with (125)I and hybridized to the salivary gland chromosomes of G. barbipes and Drosophila melanogaster. Iodinated 18 + 28 S RNA labeled three puffed sites with associated nucleoli on chromosomes IR, IIL, and IIIL of G. barbipes and the nucleolar organizer of Drosophila. Labeled 5S RNA hybridized to three sites on chromosome IIIR, two sites on chromosome IIR and one site in a Balbiani ring on chromosome IV of Glyptotendipes. Most of the label produced by this RNA was localized seven bands away from the centromere on the right arm of chromosome III, and we consider this to be the main site complementary to 5S RNA in the chironomid. This same RNA preparation specifically labeled the 56 EF region of chromosome IIR of Drosophila which has been shown previously to be the only site labeled when hybridized with homologous 5S RNA. Hybridization of G. barbipes chromosomes with iodinated 4S RNA produced no clearly localized labeled sites over the exposure periods studied. PMID- 4209868 TI - The structural basis of selective gene expression in eukaryotes. PMID- 4209869 TI - [Meningitis cerebrospinalis epidemica in Yugoslavia in the years 1925-1971]. PMID- 4209870 TI - Effect of unilateral visual deprivation on the activities of acetylcholinesterase, cholinesterase and carbonic anhydrase of the optic lobe of pigeon. PMID- 4209871 TI - Editorial: Blind children. PMID- 4209873 TI - Effects of vasopressin on toad bladder membrane proteins: relationship to transport of sodium and water. PMID- 4209872 TI - Urinary excretion of fibrinogen-related materials, complement, and immunoglobulins in proliferative glomerulonephritis and after renal transplantation. AB - Using a radial immunodiffusion technique we measured the urinary concentration of material related to complement (C3), IgM, and IgG along with fibrin-fibrinogen degradation products and heterophile (sheep) haemagglutinins in 15 patients with proliferative glomerulonephritis and in 10 patients after renal transplantation. There was a significant correlation between all variables measured, and serial studies showed that with the exception of IgG-related materials potentially useful information could be obtained on the detection of rejection and the response to treatment in both conditions. The significance of these observations is discussed. PMID- 4209874 TI - Prolactin response to thyrotrophin releasing hormone in thyrotoxicosis. PMID- 4209875 TI - Editorial: Facial hyperkinesis. PMID- 4209877 TI - Inquest on hunger-striker. PMID- 4209876 TI - Artificial feeding of prisoners. PMID- 4209878 TI - The agar gel double diffusion test for detection of the Australia antigen. PMID- 4209880 TI - The influence of dietary intake on endogenous acid production. Theoretical and experimental background. PMID- 4209879 TI - [Alpha-1 antitrypsin deficiency: correlation between biochemical tests and phenotypes in one family]. AB - Phenotypes (Pi) for serum alpha-1 antitrypsin (AAT) were determined in a family of 19 members spanning three generations and presenting a deficiency in this protein. The standard Fagerhol crossed immunoelectrophoresis procedure was used for this purpose. The individual phenotypes consisted of seven MM, three ZZ, five MZ, one SZ and three MS. AAT levels were obtained by radial immunodiffusion, trypsininhibitory capacity measurements and from cellulose acetate electrophoresis. Good correlation was found between the phenotype and the three biochemical methods for demonstrating the normal phenotype MM and the severe deficiency state ZZ. Some discrepancies were observed for the heterozygotes. It is concluded that these various assays are inaccurate for the interpretation of intermediate AAT concentrations. Since Pi typing is not suitable for use on a routine basis, it is suggested that this analysis should be performed by a specialized laboratory if intermediate deficiency is suspected. PMID- 4209881 TI - On the chemical aspects of penicillin activity. PMID- 4209882 TI - [Conclusions and recommendations on meningococcic infections elaborated by a task force assembled by the Minister of Public Health]. PMID- 4209884 TI - [Diverticulosis and diverticulitis of the large intestine (author's transl)]. PMID- 4209885 TI - [Tolerance of high doses of a new oral antidiabetic drug]. PMID- 4209883 TI - Synthesis of von Willebrand factor by cultured human endothelial cells. AB - Cultured human endothelial cells synthesize and secrete a protein(s) which has Factor VIII antigen but which lacks Factor VIII clot-promoting activity (J. Clin. Invest. 52, 2757-2764, 1973). Von Willebrand factor activity has been identified in medium from cultured human endothelial cells. This activity was demonstrated by the ability to correct the defect in platelet adhesiveness of blood obtained from patients with von Willebrand's disease. This activity also supported ristocetin-induced aggregation of washed normal human platelets. The von Willebrand factor activity from cultured endothelial cells has physicochemical and immunologic properties like those of the von Willebrand factor activity and the Factor VIII antigen present in human plasma and the Factor VIII antigen synthesized by human endothelial cells in vitro. Rabbit antibody to chromatographic fractions containing endothelial cell von Willebrand factor inhibits the platelet retention of normal blood in glass bead columns. PMID- 4209886 TI - Effect of the lesion of the mammillary bodies on the performance in the open field. PMID- 4209887 TI - [Hypothalamus of Papio papio (Desm.): stereotaxy, cytology and neurosecretory changes related to light-induced epileptic seizures]. PMID- 4209888 TI - Studies on the activated sludge bacteria participating in the biodegradation of methanol, formaldehyde and ethylene glycol. I. Isolation and identification. PMID- 4209890 TI - [Intraduodenal tube feeding in pediatrics. Technics, results, indications apropos of 50 cases]. PMID- 4209889 TI - Studies on the activated sludge bacteria participating in the biodegradation of methanol, formaldehyde and ethylene glycol. II. Utilization of various carbon and nitrogen compounds. PMID- 4209891 TI - 35Cl nuclear magnetic resonance study of zinc and phosphate binding of E. coli alkaline phosphatase. PMID- 4209892 TI - An immunochemical study of the calcium ion-binding protein (troponin-C) and the inhibitory protein (troponin-I) of the troponin complex and their interaction. PMID- 4209893 TI - Protomer stability and sclerotization in vitro. PMID- 4209894 TI - Distribution of microtubules in the golgi apparatus of Euglena gracilis. PMID- 4209895 TI - Plasticity of cortical cell firing patterns after load changes. PMID- 4209898 TI - D2O-alanine exchange reactions catalyzed by alanine racemase and glutamic pyruvic transminase. PMID- 4209896 TI - The membrane surfaces of the toad bladder: scanning and transmission electron microscopy. PMID- 4209897 TI - Neutral proteinase of rabbit skin: an enzyme capable of degrading skin protein and inducing an inflammatory response. PMID- 4209899 TI - Analytical-band centrifugation of the active form of pig kidney diamine oxidase. PMID- 4209900 TI - Biogenesis of multiple cellulase components of Pseudomonas fluorescens var. cellulosa. I. Effects of culture conditions on the multiplicity of cellulase. PMID- 4209901 TI - Staining of myofibrils with fluorescent antibody against the 10S component of the original alpha-actinin preparation. PMID- 4209903 TI - Proceeding: The site of conduction block in peripheral nerves compressed by a pneumatic tourniquet. PMID- 4209902 TI - [Bumadizone-calcium in rheumatic diseases. Clinical study]. PMID- 4209904 TI - Proceedings: Effect of prostaglandins on water transport across the isolated toad bladder. PMID- 4209906 TI - Proceedings: The effect of thyrotrophin releasing factor on the secretion of thyroid stimulating hormone and prolactin from the chicken anterior pituitary gland. PMID- 4209905 TI - Proceedings: The effect of ouabain, low temperature and exposure to Li solutions on cation fluxes in amphibian oocytes. PMID- 4209907 TI - [Study of gonorrhea. II. Clinical picture of gonorrhea in current time]. PMID- 4209908 TI - [Preliminary evaluation of anti-Rh D immunoglobulin administration]. PMID- 4209909 TI - The limitations and dangers of commerciogenic nutritious foods. PMID- 4209910 TI - The relevance of a serological classification of chronic hepatitis. PMID- 4209911 TI - HL-A antigens and some immunological parameters in psoriasis. PMID- 4209913 TI - [Gonococcic vasculitis]. PMID- 4209912 TI - [Extra-genital manifestations of gonorrhea]. PMID- 4209915 TI - Gastrointestinal transit time in ovarian carcinoma irradiated with 60Co. PMID- 4209914 TI - Chronic eosinophilic pneumonia, a manifestation of allergic aspergillosis. PMID- 4209916 TI - Estimation of the size of a T-cell-induced lytic lesion. PMID- 4209917 TI - Effect of bicarbonate on oxygen transport in juvenile diabetic ketoacidosis. PMID- 4209918 TI - Brain activity during emotional states. PMID- 4209919 TI - Prevention of adhesion in injury of the extensor mechanism of the fingers. PMID- 4209920 TI - Structure activity relationship in sixteen membered macrolide antibiotics. PMID- 4209921 TI - [Epilepsia partialis continua (Kozevnikov epilepsy)]. PMID- 4209922 TI - [Method for determination of hexosaminidases A and B in leukocytes and plasma. Application to the diagnosis of gangliosidosis A GM2]. PMID- 4209923 TI - Potential antileprotic agents. 3. Inhibition of mycobacterial dihydrofolic reductase by 2,4-diamino-5-methyl-6-alkylquinazolines. PMID- 4209924 TI - Studies of prolactin and TSH secretion by continuous infusion of small amounts of thyrotropin-releasing hormone (TRH). PMID- 4209925 TI - The use of 4-6 MeV electrons for the conservative treatment of retinoblastoma. PMID- 4209926 TI - The ultrastructure of the human placental bed. PMID- 4209927 TI - The surgical treatment of carcinoma of the oesophagus. PMID- 4209928 TI - Diphtheria toxin and mutant proteins. PMID- 4209929 TI - Stereochemistry and toxicity of cord factor. PMID- 4209930 TI - Enhancement of cord factor-toxicity by sulfolipid. PMID- 4209931 TI - Evaluation of some morphological characteristics of spores of two species of Microsporida by scanning electron microscope and freeze-etching techniques. PMID- 4209932 TI - Functional and electron microscopic changes in the trabecular meshwork remaining after trabeculectomy in cynomolgus monkeys. PMID- 4209934 TI - Studies on the mouse mammary tumour agent (MTA). IV. Lactate and malate dehydrogenase isozymes in normal mammary gland of R3f, C57BL and in virus-induced and spontaneous mammary adenocarcinoma in C57BL and R3 mouse strains. PMID- 4209933 TI - Failure to induce autoimmune disease with neonatal bursectomy in chickens. PMID- 4209935 TI - Distribution of alkaline phosphatase in the digestive system of a few teleost fishes. PMID- 4209936 TI - [Ultrafine structure and division of the macronuclei of the infusorian Dileptus anser]. PMID- 4209937 TI - [Genetic polymorphic systems of human blood as biological markers and their relation ot he course of pregnancy and the menstrual cycle]. PMID- 4209938 TI - Mechanisms regulating ovarian cycle in the toad Bufo bufo bufo (L): role of presence of second growth phase oocytes in controlling recruitment from pool of first growth phase oocytes. PMID- 4209939 TI - Some biological and morphological characteristics of the agent 3053 LB isolated from the plasma of a leukemic cow. PMID- 4209940 TI - [Relations between metabolic acidosis and intraocular pressure after inhibition of carboanhydrase with acetazolamide (author's transl)]. PMID- 4209941 TI - Roentgenologic determination of foetal maturity. PMID- 4209943 TI - Secretion of collagen by corneal epithelium. II. Effect of the underlying substratum on secretion and polymerization of epithelial products. PMID- 4209942 TI - Microcalorimetry applied to certain species of bacteria growing in sterilized separated milk. PMID- 4209944 TI - Incorporation of 3H-thymidine in rhesus monkey (Macaca mulatta) embryos. PMID- 4209945 TI - Antibodies against Sertoli cells in human infertility. PMID- 4209946 TI - Endogenous endotoxemia during hemorrhagic shock in the subhuman primate. PMID- 4209947 TI - Postoperative nutrition and colonic wound healing, serum protein metabolism, and body weight. PMID- 4209948 TI - Insulin response in patients undergoing prolonged intravenous hyperalimentation. PMID- 4209949 TI - Cortisol responses to normotensive and hypotensive oligemia in unanesthetized primates. PMID- 4209950 TI - Treatment of acute renal failure with intravenous administration of essential amino acids and glucose. PMID- 4209952 TI - Pulmonary function studies with Xenon 133 after orthotopic cardiopulmonary autotransplantation in primates. PMID- 4209951 TI - Portacaval shunt in established experimental mammary carcinoma. PMID- 4209954 TI - Gastrin response to feeding. PMID- 4209953 TI - Acid and gastrin response to acute hypercalcemia in conscious monkeys. PMID- 4209955 TI - An inhibitor, obtained from primates, of gastrin-stimulated gastric acid in rats. PMID- 4209956 TI - External compression of the cardia related to gastroesophageal reflux. PMID- 4209957 TI - Cerebral blood flow and its responsiveness to arterial PCO2: alterations before and after experimental head injury. PMID- 4209958 TI - Normothermic vs hypothermic perfusion in treatment of acute experimental spinal cord injury. PMID- 4209959 TI - Middle cerebral arterial spasm from subarachnoid blood: spasmolysis with topical use of nitroglycerin. PMID- 4209960 TI - Long-term recording of primate cochlear potentials through an inner ear electrode implant. PMID- 4209961 TI - Effect of cryosurgery on the tympanic membrane. PMID- 4209962 TI - Correlation between buccal smear abnormalities and serum protein levels in infants suffering from protein calorie malnutrition and vitamin A deficiency. PMID- 4209963 TI - Non-reciprocal intragenic mitotic recombination in Drosophila melanogaster. PMID- 4209964 TI - The genetics of some second chromosome melanotic tumour mutants of Drosophila melanogaster. PMID- 4209965 TI - [Study of the concentration of immunoglobulins in staphylococcal destruction of the lungs in children]. PMID- 4209966 TI - [The first renal transplantation. Emerich Ullmann (1861-1937) (author's transl)]. PMID- 4209967 TI - Glycoside conjugative activity in different insect and vertebrate species. PMID- 4209968 TI - Detection of metabolic carcinogen intermediates in urine of carcinogen-fed rats by means of bacterial mutagenesis. PMID- 4209969 TI - Nitroglycerin-induced suppression of excitation of afferent cardiac sympathetic nerves during myocardial ischemia. PMID- 4209971 TI - Protein-calorie malnutrition. A host determinant for Pneumocystis carinii infection. PMID- 4209972 TI - Further investigations on pulsatile movements in the cerebrospinal fluid pathways. PMID- 4209970 TI - Regulation of neutral protease productivity in Bacillus subtilis: transformation of high protease productivity. AB - A transformable strain of Bacillus subtilis 6160, a derivative of B. subtilis 168, produces three kinds of casein hydrolytic enzymes (alkaline protease, neutral protease, and esterase) in a culture medium. B. natto IAM 1212 produces 15 to 20 times as much total proteolytic activity as does B. subtilis. Extracellular proteases produced by the two strains were separated into each enzyme fraction by diethylaminoethyl-Sephadex A-50 column chromatography. The difference in the total protease activities of extracellular proteases between the two strains was due to the amount of neutral protease. The ratios of neutral protease activity to alkaline protease activity (N/A) were 1.1 in B. subtilis 6160 and 13.0 in B. natto IAM 1212. Enzymological and immunological properties of alkaline protease and neutral protease obtained from the two strains were quite similar or identical, respectively. Specific activities measured by an immunological analysis of the two neutral proteases against casein were also equal. A genetic character of high protease productivity in B. natto IAM 1212 was transferred to B. subtilis 6160 by the deoxyribonucleic acid-mediated transformation. Among 73 transformants that acquired high protease productivity, 69 produced a higher amount of neutral protease and the ratios of N/A were changed to 15 to 60. Three other strains were transformed in the productivity of neutral protease and alpha-amylase simultaneously, and one showed considerable change in the production of alkaline protease and neutral protease. The specific activities (casein hydrolytic activities/enzyme molecules) of neutral proteases from the representative four transformants were equal to those of the two parental strains. These results suggested the presence of a specific gene(s) that participated in the productivity of neutral protease in B. subtilis. PMID- 4209973 TI - The healing of experimentally induced pulpitis. PMID- 4209974 TI - M-protein. PMID- 4209975 TI - [Reliability of the tuberculin scarification test in the systematic search for tuberculous contamination in school populations (author's transl)]. PMID- 4209976 TI - Problems of immunology in myasthenia, polymyositis and Guillain-Barre syndrome. PMID- 4209977 TI - [Pulmonary tuberculosis resistant to streptomycin and isoniazid and treated wtih a combination of ethionamide, pyrazinamide, and cycloserine (200 cases)]. PMID- 4209978 TI - [Female genital infections at Dakar (preliminary note)]. PMID- 4209979 TI - [Case of Waldenstrom's disease with predominantly digestive symptomatology]. PMID- 4209980 TI - [Results of an etiological survey of female genital infections in rural areas of Senegal]. PMID- 4209981 TI - [Population dynamics of Telenomus fariai, a parasite of the Chagas' disease vectors]. PMID- 4209982 TI - Immunoglobulins of the Indian buffalo. PMID- 4209983 TI - Absorption spectra of algal and chloroplast suspensions: a simple method using conventional spectrophotometers. PMID- 4209984 TI - [Study of the antigenic relations between Yersina enterocolitica serotype 9 and other gram negative bacterial strains]. PMID- 4209985 TI - Letter: Biological effects of azomycin (2-nitro-imidazole): inhibition of ribonucleotide reductase. PMID- 4209986 TI - [Cooperative study on the long-term treatment of osteoporosis with small doses of thyrocalcitonin. Apropos of 55 cases]. PMID- 4209987 TI - [Apparently inflammatory early degenerative polyarthropathy]. PMID- 4209988 TI - [Role of immunological studies in the diagnosis of chronic hepatopathies]. PMID- 4209989 TI - Antibody deficiency syndromes in children. Analysis of serum immunoglobulins in 1170 hospitalized children. PMID- 4209990 TI - Chromatographic separation and serologic analysis of antibodies in the sera of mothers with ABO incompatibility. PMID- 4209991 TI - Influence of Corynebacterium diphtheriae and pseudodiphtheriae on embryonic quinea pig cell cultures. II. Ultrastructural studies on infected culture cells. PMID- 4209992 TI - Enzymatic repair of deoxyribonucleic acid; the biochemical and biological repair properties of a deoxyribonucleic acid polymerase from micrococcus luteus. PMID- 4209993 TI - [Alpha-1-fetoprotein--diagnostic significance. Determination using radioimmunoassay and migration-immunoelectrophoresis]. PMID- 4209994 TI - The enzymic and non-enzymic degradation of colneleic acid, an unsaturated fatty acid ether intermediate in the lipoxygenase pathway of linoleic acid oxidation in potato (Solanum tuberosum) tubers. AB - Colneleic acid is an unsaturated ether fatty acid derived from linoleic acid via a lipoxygenase-mediated enzyme pathway. It is degraded (a) by an enzyme in potato tubers which is heat-labile and non-dialysable and (b) by a model system containing catalytic amounts of Fe(2+) ions. Both enzyme- and Fe(2+)-catalysed systems have similar properties with respect to pH optima (pH5.0-5.5), oxygen requirement (0.6-0.7 mol of O(2) consumed/mol of ether degraded), inhibitors and reaction products. An unstable product breaks down to C(8) and C(9) carbonyl fragments. Both systems are inhibited by low concentrations of antioxidants (e.g. 5mum-butylated hydroxytoluene) and some chelating agents (e.g. 5mum-diethyldithio carbamate). The model system is strongly inhibited by metal ions, particularly Cu(2+) and Fe(3+), at 20mum. Hydrogen peroxide and haemoproteins do not substitute for the enzyme or Fe(2+) ions but the non-haem iron protein, ferredoxin, does catalyse the degradation. PMID- 4209995 TI - [Cerebral ictus and dihydroergotoxin methanesulfonate: a year of therapeutic trial]. PMID- 4209996 TI - [Proceedings: 306. Studies on amine metabolism in various regions of monkey brain after the administration of amine precursors (author's transl)]. PMID- 4209997 TI - Proceedings: 313. Unit activity of the prefrontal cortex and light-lever press reaction. PMID- 4209998 TI - [Proceedings: 399. The olfactory center in the frontal lobe of the monkey (author's transl)]. PMID- 4209999 TI - New problems in sonar diagnosis in obstetrics and gynecology. PMID- 4210000 TI - Pathophysiology of Salmonella diarrhea in the Rhesus monkey: Intestinal transport, morphological and bacteriological studies. PMID- 4210001 TI - A physiological model to study gallbladder function in primates. PMID- 4210002 TI - Letter: Long-term parenteral nutrition. PMID- 4210003 TI - Cost of medical care in a practice of internal medicine. A study in a group of seven internists. PMID- 4210004 TI - Letter: Pheochromocytoma and hyperparathyroidism. PMID- 4210005 TI - Amoxicillin: in vitro susceptibility of "blood culture strains" of gram-negative bacilli and comparisons with penicillin G ampicillin, and carbenicillin. PMID- 4210006 TI - Amoxicillin in the treatment of uncomplicated gonococcal urethritis in males. PMID- 4210007 TI - Determination of blood acetylcholinesterase inhibition caused by reversible inhibitors in vivo. PMID- 4210008 TI - Minicells of Bacillus subtilis. A unique system for transport studies. PMID- 4210009 TI - Letter: Acute brucellosis presenting as epididymo-orchitis. PMID- 4210010 TI - Diabetic ketoacidosis presenting as neurosurgical emergencies. AB - Three cases of ketoacidosis in previously unsuspected diabetics are described. Each was admitted to hospital as a neurosurgical emergency. The recognition of this rare presentation is stressed since prompt treatment of the metabolic disturbance rapidly resolves the neurological abnormality. PMID- 4210011 TI - Contamination of blood cultures from a commercial beta-lactamase preparations. PMID- 4210012 TI - The bladder lymphatics. A study of drug transport. PMID- 4210013 TI - Serum beta 2-glycoprotein 1 phenotype frequencies in an English population. PMID- 4210014 TI - Mannose phosphate isomerase: additional variants in primates. PMID- 4210015 TI - [3-(aminoalkyl)-silanes--new class of antimicrobial substances]. PMID- 4210016 TI - A method for cloning anchorage-dependent cells in agarose. PMID- 4210017 TI - Plant carbonic anhydrase. Properties and carbon dioxide hydration kinetics. PMID- 4210019 TI - Potatoes and spina bifida. PMID- 4210018 TI - Structure of immunoglobulin A. Cysteine-containing peptides of the alpha chain of an immunoglobulin A-1 myeloma protein. PMID- 4210020 TI - [Histotopochemistry of the islet organ (Langerhans) of the pancreas in Wister rats. IV. Studies on heavy metal content]. PMID- 4210021 TI - The TSH, FSH and prolactin responses to continuous infusions of TRH and the effects of oestrogen administration in normal males. PMID- 4210022 TI - Thyroid function in euthyroid subjects with autonomous thyroid nodules. PMID- 4210023 TI - Control of sn-glycerol 3-phosphate oxidation in brown adipose tissue mitochondria by calcium and acyl-CoA. PMID- 4210024 TI - Disc-gel electrophoresis of plus and minus strains and of gymnothecial cultures of Arthroderma tuberculatum. PMID- 4210025 TI - Effect of dimethyl sulfoxide on natural resistance to bacterial infections in mice. PMID- 4210026 TI - Ultrastructure of Rhodospirillum rubrum after freeze-etching. PMID- 4210027 TI - [Insulin secretion after administration of sulfonylurea in normal and diabetic subjects]. PMID- 4210028 TI - [Biochemical and immunochemical properties of human placental lactogen: hPL, human chorionic somatomammotropin: hCS. 3. Immunological character and its clinical application]. PMID- 4210029 TI - [Determination of prolactin]. PMID- 4210031 TI - [Dynamics of prolactin in human blood]. PMID- 4210030 TI - [Secretion dynamics of prolactin in livestock]. PMID- 4210032 TI - [Case of spontaneous hypoparathyroidism]. PMID- 4210033 TI - Mutagenic activity of the insecticide oxydemetonmethyl in a resistant strain of Drosophila melanogaster. PMID- 4210034 TI - [Combined radiologic and antibiotic therapy of scleroma]. PMID- 4210035 TI - Titration of precipitating antibody in equine infectious anemia. PMID- 4210036 TI - Bacillus cereus outgrowth "early proteins" and their possible role in control of transcription. PMID- 4210037 TI - Genetic analysis of rec mutants of Bacillus subtilis. Evidence for at least six linkage groups. PMID- 4210038 TI - Multi-locus polymorphism and selection in a population of Drosophila melanogaster. I. Linkage disequilibrium on chromosome 3. PMID- 4210039 TI - Ankle sprains in young athletes. Relation of severity and disability. PMID- 4210040 TI - [Induction by the oncornavirus LPV of a systemic pathological process in monkey hematopoietic organs]. PMID- 4210041 TI - Quantitative cytochemical estimation of the effect of pentagastrin (0.005-5 pg ml) and of plasma gastrin on the guinea-pig fundus in vitro. PMID- 4210042 TI - Effects of 5-bromodeoxyuridine on rat embryo cell cultures. PMID- 4210043 TI - Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. A morphological and histochemical study of the pars recta during malonate poisoning. PMID- 4210044 TI - Quantitative changes in mitochondria of guinea pig myocardium following anaesthesia with halothane. PMID- 4210045 TI - [Fine structure of the activated chief cell of the human parathyroid gland as visualized by freeze-fracture (author's transl)]. PMID- 4210047 TI - [Role of TSH determination in thyroid diseases]. PMID- 4210046 TI - Urinary acidification and carbonic anhydrase distribution in bladders of Dominican and Colombian toads. PMID- 4210049 TI - [Remote results of a 1-stage surgical excision of an esophageal diverticulum]. PMID- 4210048 TI - [Detection of antibodies to soluble nucleoprotein and to deoxyribonucleic acid using a radioimmunologic method]. PMID- 4210050 TI - Clinical assessment of glybenclamide (daonil) in diabetes mellitus. PMID- 4210051 TI - [The rate of destruction of sensitive mycobacteria as a factor in the development of resistance in cavitating pulmonary tuberculosis]. PMID- 4210052 TI - [The binding of labelled thyroxine on protein of estrogenized rat adenohypophysis in vitro: kinetics of displacement by stabile thyroxine (author's transl)]. PMID- 4210053 TI - Neurofibromatosis with meningioma orbit (a case report). PMID- 4210054 TI - [Bone formation in a surgical scar]. PMID- 4210055 TI - [Chagas' disease and schistosomiasis mansoni as causes of rejection of employment applicants]. PMID- 4210056 TI - [Infection of HeLa cells by the nucleic acids of LPP group algophages]. PMID- 4210057 TI - [Identification of LPP-1 virus isolates separated from artificial Dnieper reservoirs]. PMID- 4210058 TI - Comparative scrapie activity of brain material and cerebrospinal fluid from scrapie-affected rats. PMID- 4210059 TI - TRH stimulated TSH response in euthyroid healthy subjects and patients with thyroid dysfunction. PMID- 4210060 TI - A comparative study on drug hydroxylation and glucuronidation in liver microsomes of phenobarbital and 3-methylcholanthrene treated rats. PMID- 4210061 TI - Urine homovanillic acid and tissue dopa oxidase in patients with melanoma. PMID- 4210062 TI - The RBE of neutrons in vivo. PMID- 4210063 TI - Biological characterization of a high energy neutron beam for radiation therapy. PMID- 4210065 TI - A report on three years' fast neutron therapy from the Medical Research Council's cyclotron at Hammersmith Hospital, London. PMID- 4210064 TI - Localization error in the radiotherapy of Hodgkin's disease and malignant lymphoma with extended mantle fields. PMID- 4210066 TI - An experimental model for chronic communicating hydrocephalus. PMID- 4210067 TI - Sequential changes of vascular ultrastructure in experimental cerebral vasospasm. Myonecrosis of subarachnoid arteries. PMID- 4210068 TI - Extradural ossification following an extradural hematoma. Case report. PMID- 4210069 TI - Effects of operantly conditioning epileptic unit activity on seizure frequencies and electrophysiology of neocortical experimental foci. PMID- 4210072 TI - Recent research on malaria in mammals excluding man. PMID- 4210073 TI - New knowledge of toxoplasma and toxoplasmosis. PMID- 4210074 TI - The influence of ovarian sonication on fetal development in the rat. PMID- 4210075 TI - Errors in performance and interpretation of echocardiograms. PMID- 4210076 TI - The pancreatic beta-cell recognition of insulin secretagogues. Comparisons of glucose with glyceraldehyde isomers and dihydroxyacetone. PMID- 4210077 TI - Isolation of ferritin from human mammary and pancreatic carcinomas by means of antibody immunoadsorbents. PMID- 4210078 TI - Effect of vitamin B-12 deprivation on the rates of synthesis and degradation of rat liver fatty acid synthetase. PMID- 4210079 TI - Chemical and physical properties of a carotenoprotein from Rhodospirillum rubrum. PMID- 4210080 TI - Studies on Fd-fragments of human immunoglobulins. II. The preparation and characterization of peptic (Fab')2-fragments and an Fd'-fragment of IgA-myeloma proteins. PMID- 4210081 TI - The influence of magnesium on the chlorophyll fluorescence yield of isolated chloroplasts. PMID- 4210082 TI - [Synthesis of ethyl esters of NTA, EDTA, DTPA and pyridine-2,6-dicarboxylic acid using the diethyl ester of pyrocarbonic acid]. PMID- 4210083 TI - Studies of serum from patients with breast cancer. PMID- 4210084 TI - Studies on dextranase. II. New exo-dextranase from Brevibacterium fuscum var. Dextranlyticum. PMID- 4210085 TI - The sulfhydryl groups of porcine pancreatic alpha-amylase: unmasking, reactivity and function. PMID- 4210087 TI - DNA-dependent poly (G) synthesizing activities in DNA-dependent RNA polymerase fractions from cauliflower inflorescence. PMID- 4210086 TI - Activation energy of glucuronide biosynthesis. PMID- 4210088 TI - [Proceedings: Determination of Factor XIII (fibrin-stabilizing factor) in plasma and blood platelets]. PMID- 4210090 TI - Therapy of uncomplicated gonococcal urethritis in the male with a single dose of amoxicillin. PMID- 4210089 TI - Single-dose oral therapy for uncomplicated gonorrhea: comparison of amoxicillin and ampicillin given with and without probenecid. PMID- 4210091 TI - Treatment of uncomplicated gonorrhea in women with a single dose of amoxicillin. PMID- 4210092 TI - Treatment of uncomplicated gonorrhea with amoxicillin. PMID- 4210093 TI - [Binding of the reticuloendotheliotropic vital dye-stuffs lithium carmine and trypan blue to plasma proteins]. PMID- 4210094 TI - Experimental Pseudomonas granuloma in the skin of guinea pigs. PMID- 4210095 TI - Changed pattern of transcription and replication in polytene chromosomes of Drosophila melanogaster resulting from eu-heterochromatin rearrangement. PMID- 4210097 TI - The trypanosomes of anura. PMID- 4210096 TI - Comparative study of the function of polytene chromosomes in laboratory stocks of Drosophila melanogaster and the l(3)tl mutant (lethal tumorous larvae). I. Analysis of puffing patterns in autosomes of the laboratory stock Batumi-L. PMID- 4210098 TI - Diagnostic ultrasound in radiation treatment planning. PMID- 4210099 TI - Metabolism of carbaryl by selected human tissues using an organ-maintenance technique. PMID- 4210100 TI - Prednisolone-induced mucormycosis in rhesus monkeys. PMID- 4210101 TI - Mycologic, serologic and histologic findings in bovine abortion associated with Allescheria boydii. PMID- 4210102 TI - Lymphocyte stimulation in Candida albicans infections. PMID- 4210103 TI - Effect of estrogen on serum total and free thyroxine and triiodothyronine in a thyroxine-binding globulin deficient family. PMID- 4210104 TI - Growth of measles virus in nervous tissues. II. Neurotropic properties of a SSPE virus in hamsters. PMID- 4210105 TI - Normal values of the serum protein fractions in cynomolgus monkeys used as experimental animals. PMID- 4210106 TI - Recent developments in magnesium research in pediatrics. PMID- 4210107 TI - Glutathione reductase in the sea urchin egg. II. Cleavage-associating fluctuation of the activity and its possible regulatory mechanism. PMID- 4210108 TI - [Three-year experience with the antidiabetic glibornurid (Glutril)]. PMID- 4210110 TI - [Influence of natural bones on the dose distribution of electrons and photons up to 42 MeV]. PMID- 4210109 TI - Evidence of homology between the beta-chain of human haptoglobin and the chymotrypsin family of serine proteases. PMID- 4210111 TI - Management of urinary tract infection in acute paraplegic patients with special reference to the paper strip screening test for infection. PMID- 4210112 TI - [Problems of diabetes in pregnancy]. PMID- 4210113 TI - The incidence of ABO and Rh blood groups in the Bellary area--a random survey. PMID- 4210114 TI - Haemorrhagic complications after penicillin therapy. PMID- 4210115 TI - The patterns of infection in cystic fibrosis. PMID- 4210116 TI - Faulty proteins: altered gene products in senescent cells and organisms. PMID- 4210117 TI - Circulatory effects of intravenously administered rolitetracycline and other tetracyclines in animal experiments. PMID- 4210118 TI - [Values of acidobasic indices in sheep]. PMID- 4210119 TI - Different immunofluorescent titres of Candida albicans blastospores and pseudohyphae. PMID- 4210120 TI - [Calcemia, phosphoremia, magnesiemia, natremia and kalemia during a course of nutritional muscular dystrophy in young cattle]. PMID- 4210121 TI - [Physical, chemical and serological properties of Brucella IgG1 and IgG2 antibodies in cattle]. PMID- 4210123 TI - [Anesthesia using a mixture of chloral hydrate, magnesium sulfate and pentobarbital in horses]. PMID- 4210122 TI - [Effect of halothane anesthesia without surgery on the activity of GOT, GPT, SODH and AP enzymes in goats]. PMID- 4210124 TI - Genetic improvement of plant protein. PMID- 4210125 TI - Accumulation of dietary polychlorinated biphenyls (Aroclor 1254) by rainbow trout (Salmo gairdneri). PMID- 4210126 TI - Reflex (sensory precipitation) epilepsy (review and case report). PMID- 4210127 TI - Immunological studies in lymphoma patients IX. Detection of antimycotic antibodies. PMID- 4210128 TI - Comparative in vitro activity of kanendomycin, kanamycin, gentamicin and streptomycin against 100 consecutive cultures of tubercle bacilli recovered from patients. PMID- 4210129 TI - National health insurance proposals: which one will it be? PMID- 4210130 TI - Agar ingestion and serum bilirubin values in newborn infants. PMID- 4210131 TI - [Oxygen demand of thermophilic and mesophilic bacteria]. PMID- 4210132 TI - [Esophageal diverticula. Apropos of 221 cases]. PMID- 4210133 TI - [On acidoketosis and hypoglycemic comas in diabetic children]. PMID- 4210134 TI - [Clinical and radiological considerations of 4 cases of isolated posterior marginal fractures of the distal tibial epiphysis]. PMID- 4210135 TI - [Results obtained in sterilization of carriers of beta hemolytic streptococcus, group A, with penicillin V]. PMID- 4210136 TI - [Vaginal flora in pregnancy]. PMID- 4210137 TI - [Possibilities in the differentiation of cows resistant and susceptible to Streptococcal mastitis through the analysis of lipids in the lactosebum from the teat canal]. PMID- 4210138 TI - [Development of serum lipase activity in calves in the early post-natal period]. PMID- 4210139 TI - [Nitrates in the blood, urine and organs of domestic animals]. PMID- 4210140 TI - [Changes in the distribution of urea in body fluids of sheep, as influenced by various levels of protein nitrogen intake]. PMID- 4210141 TI - [Morphology of bronchopulmonary aspergillosis in roe deer and hares]. PMID- 4210142 TI - [Comparison of the effectiveness of Marek's disease virus isolation from lymphocytes and spleen cells in chickens]. PMID- 4210143 TI - [Fermentative properties of the species Streptococcus dysgalactiae]. PMID- 4210144 TI - [Microsporia of cats and dogs caused by the Dermatophyte Microsporum canis bodin]. PMID- 4210145 TI - A method to demonstrate the specificity and sensitivity of fluorescent antibody by immunoelectrophoresis and immunodiffusion using ultraviolet light photography. PMID- 4210146 TI - Electroimmunodiffusion on cellulose acetate: a rapid method for analysis of bovine lactoferrin in chromatography effluents. PMID- 4210147 TI - Isolation and purification of an organ-specific autoantigen from rabbit seminal plasma. PMID- 4210148 TI - Uptake of glibornuride by microdissected pancreatic islets. PMID- 4210150 TI - Coatings as barriers to prevent polychlorinated biphenyl contamination of silage. PMID- 4210149 TI - Letter: Effects of formaldehyde and glutaraldehyde fixation on the monoamine oxidase activity in isolated rat liver mitochondria. PMID- 4210153 TI - Effect of photooxidative conditions on levels of superoxide dismutase in Anacystis nidulans. PMID- 4210151 TI - Transcription of mammalian satellite DNAs by homologous DNA-dependent RNA polymerases. PMID- 4210152 TI - [Juvenile xanthogranuloma associated with Von Recklinghausen's disease]. PMID- 4210154 TI - Effects of 60Co gamma irradiation on aflatoxin B1 and B2 production by Aspergillus flavus. PMID- 4210155 TI - Analysis of herbicides. PMID- 4210156 TI - Synthesis of 3'-amido-3'-deoxyadenosine 3',5'-cyclophosphate. PMID- 4210157 TI - Specificity of purified hemagglutinin (lectin) from Lotus tetragonolobus. PMID- 4210158 TI - Exchange within heterozygous inversions in Drosophila melanogaster. AB - The exchange behavior of non-attached, whole arm, X chromosome inversions was reexamined using nondisjunction in XXY females as an indirect measure of the frequency of nonexchange tetrads. Crossing over is quite normal in these inversion heterozygotes and is independent of the arrangement of the basal heterochromatin. PMID- 4210159 TI - Complementation analysis of late lethal mutants of Drosophila melanogaster. AB - Late larval and pupal lethal mutants of Drosophila define those gene functions which are essential for the development of pupae (metamorphosis) but not for embryonic or larval development. In a previous report the isolation of a large number of such mutants was outlined, and a description of the imaginal disc defects in those mutants was described. This report concerns genetic analysis of those mutants. 3746 different pairwise combinations of mutants have been tested for complementation. Only 10 pairs fail to complement. In all of the cases tested, the lethal mutation in each member of a non-complementing pair has a similar map location. In addition to the non-complementing pairs one group of seven partially-complementing mutants has been identified. Comparisons of the imaginal disc defects within the non-complementing pairs and the lethal hybrids formed by the respective pairs were made to test for uniformity of phenotype. No significant qualitative differences were detected between any non-complementing pairs or their respective hybrids. PMID- 4210161 TI - Marginal leakage of various restorative materials. PMID- 4210162 TI - Hypertension detection by dentists. PMID- 4210160 TI - Tay-Sachs' disease and Fabry's disease: clinical and chemical diagnosis of two metabolic eye diseases. PMID- 4210163 TI - [TRH test I. A review of the clinical diagnostic use of the thyrotropin releasing hormone]. PMID- 4210164 TI - [TRH test II. Stimulation with thyrotropin releasing hormone(TRH) in patients with thyroid diseases]. PMID- 4210166 TI - Seizures in patients over the age of 40: a general hospital study. PMID- 4210165 TI - [Effects of thyrotropin releasing hormone (TRH) in normal subjects and in patients with thyroid gland diseases]. PMID- 4210167 TI - [Tuberculosis in children caused by primary inoculation of the skin and mucous membranes]. PMID- 4210169 TI - Computer-aided three-dimensional reconstruction and quantitative analysis of cells from serial electron microscopic montages of foetal monkey brain. PMID- 4210168 TI - Electrocardiogram as a guide to potassium replacement in diabetic ketoacidosis. PMID- 4210170 TI - Cecal diverticulum strangulated in femoral hernia. PMID- 4210171 TI - Amniotic fluid tests for fetal maturity. PMID- 4210172 TI - Development of enteric parasites in parenterally fed rats. PMID- 4210173 TI - Stimulation of prolactin and growth hormone release by TRH infused into a hypophysial portal vessel. PMID- 4210174 TI - Relationship of ambient temperature to serum prolactin in heifers. PMID- 4210175 TI - Intravenous hyperalimentation. PMID- 4210176 TI - [Comparative characteristics of the polynucleotide-peptide complexes isolated from various species of algae]. PMID- 4210177 TI - [Dissolution of gold by microorganisms and the products of their metabolism]. PMID- 4210178 TI - [Comparative study of the pigment makeup of 3 fluorescing species of Pseudomonas]. PMID- 4210180 TI - The social context of coronary artery surgery. PMID- 4210179 TI - The diagnosis of myocardial infarction in the Wolff-Parkinson-White syndrome. PMID- 4210181 TI - The effects of extraoral low-pull traction to the mandibular dentition of Macaca mulatta. PMID- 4210182 TI - Neuromuscular and skeletal adaptations to altered function in the orofacial region. PMID- 4210183 TI - Gastric clearance of serum albumin in normal man and in certain gastroduodenal disorders. AB - Serum albumin gastric loss was estimated from the measurement of non-dialysable radioactivity of the gastric juice after intravenous injection of radioiodinated serum albumin (RISA). Immunochemical quantitation of serum albumin was performed in some of the samples. In the control group, the mean gastric clearance of albumin was 1.71 ml per hour with a range of 0.41 to 4.41 ml per hour. This represented a gastric loss of 1.9 gram of albumin per day and 11% of the daily degradation of albumin. There was no significant change in the gastric albumin loss after stimulating the gastric secretion. No significant difference in the gastric albumin leakage was found between normal subjects and patients with gastric or duodenal ulcer. IN PERNICIOUS ANAEMIA ALBUMIN LOSS INTO THE STOMACH WAS GREATER (MEAN: 3.72 ml per hour; SD 1.52 ml) than in the normal group and accounted for the greater albumin fractional catabolic rate. This fact had never been proved before. In both patients with giant rugae of the gastric mucosa the gastric clearance of serum albumin was also increased. It is concluded first that albumin is not secreted by the chief and parietal cells of the mucosa and probably passes through the gastric wall between the cells of the mucosa, perhaps during the exfoliation of the surface epithelial cells, and secondly that the stomach is one of the sites of serum albumin breakdown, a fact that supports the view that the gastrointestinal tract plays a major role in the catabolism of serum albumin. PMID- 4210184 TI - Dietary fat and coronary heart disease: A review. I. Diet in the prevention of coronary heart disease and some pathogenetic aspects. PMID- 4210185 TI - Resistance of Neisseria gonorrhoeae to penicillin in 199 gonococcal infections in women and the response of those infections to penicillin treatment. PMID- 4210186 TI - [Effect of polychemotherapy on the activity of certain metalloenzymes in the blood in lung cancer]. PMID- 4210187 TI - [Leukemia in neurofibromatosis patients]. PMID- 4210188 TI - Physical changes in the bone tissue of the skull due to head injury. PMID- 4210189 TI - [The erythrocyte sedimentation rate (ESR) and treatment with neuroleptics]. PMID- 4210190 TI - [Rectal localization of Recklinghausen's neurofibromatosis. Report of an anatomo clinical observation]. PMID- 4210191 TI - [Clinical and pathological aspects of angiokeratoma corporis diffusum Fabry. Report of a case]. PMID- 4210193 TI - The role of insulin and growth hormone in fetal growth. PMID- 4210194 TI - Letter: Comparison of pain cry in neonates with and without feeding tube. PMID- 4210192 TI - Kinetic behavior of enzymes in artificial membranes. Inhibition and reversibility effects. PMID- 4210195 TI - Dominant afferentation and quantitative reorganization of auditory and visual analyzers in the brainstem of carnivores and primates, including man. PMID- 4210196 TI - Stepping movements evoked by repetitive dorsal root stimulation in a mesencephalic cat. PMID- 4210198 TI - Effect of caffeine on crossing-over in Drosophila melanogaster. PMID- 4210197 TI - Cortico-mamillary tracts of the brain. PMID- 4210200 TI - Antigenicity of normal and tumoral glycoproteins correlated with their action on serum glycoproteins. PMID- 4210201 TI - The influence of radiation on blood vessels and circulation. Chapter VII. Functional response of heart and major vessels. PMID- 4210202 TI - Actions of lithium ions and insulin on glucose utilization, glycogen synthesis and glycogen synthase in the isolated rat diaphragm. PMID- 4210199 TI - Report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry. PMID- 4210203 TI - Special needs of long-term patients. PMID- 4210205 TI - [Evolution of indications of exchange transfusion in the newborn. Criteria for renewed transfusion (apropos of 1200 cases)]. PMID- 4210204 TI - [Frequency of isolated IgA deficits in the normal population. Study of 15200 blood donnors]. PMID- 4210206 TI - [Letter: Surprises in routine group determination]. PMID- 4210207 TI - [ABO and Rh (D) blood groups in the Turkish population]. PMID- 4210208 TI - [The place of a peripheral vasodilator agent in the treatment of shock states]. PMID- 4210209 TI - Cleavage of actin by thrombin. AB - Under certain conditions actin can be split by thrombin. Actin prepared in the presence of excess Ca(++) was found to be resistant to thrombin. However, if actin was purified without added Ca(++), both G- and F- actin underwent thrombic digestion, although a considerable proportion of actin molecules remained intact. Similar results were obtained with actin (in 50% sucrose) devoid of nucleotide and divalent cations but retaining its native characteristic. The removal of tightly bound Ca(++) from actin by EDTA accelerated the thrombic splitting and made the complete fragmentation of G-actin possible. Thrombin first cleaves actin into two pieces and subsequently one of them, fragment K (molecular weight 37,000 on sodium dodecyl sulfate-polyacrylamide gel), splits further, resulting in fragments L (molecular weight 27,000) and M (molecular weight about 10,000). PMID- 4210210 TI - Actin antibody: the specific visualization of actin filaments in non-muscle cells. AB - Actin purified from mouse fibroblasts by sodium dodecyl sulfate gel electrophoresis was used as antigen to obtain an antibody in rabbits. The elicited antibody was shown to be specific for actin as judged by immunodiffusion and complement fixation against partially purified mouse fibroblast actin and highly purified chicken muscle actin. The antibody was used in indirect immunofluorescence to demonstrate by fluorescence light microscopy the distribution and pattern of actin-containing filaments in a variety of cell types. Actin filaments were shown to span the cell length or to concentrate in "focal points" in patterns characteristic for each individual cell. PMID- 4210212 TI - Functional differences in the multiple hemocyanins of the horseshoe crab, Limulus polyphemus L. AB - Hemocyanin in the hemolymph of the horseshoe crab, Limulus polyphemus L., is a high-molecular-weight copper protein which binds oxygen cooperatively and shows a higher oxygen affinity at pH 7 than at pH 9. Treatment with EDTA (ethylenediaminetetra-acetate) disaggregates the hemocyanin molecules and abolishes both the reverse Bohr effect and cooperative oxygen binding. Chloride ions interact with the EDTA-treated material and, in the presence of saturating amounts of NaCl, a reverse Bohr effect is restored, but cooperativity is not. The EDTA-treated hemocyanin contains at least five electrophoretically distinct hemocyanins. These hemocyanins have similar molecular weights (about 66,000) but are functionally dissimilar. They have different oxygen affinities and different responses to chloride ions. The effect of chloride ions on unfractionated hemocyanin is due to pH-dependent chloride interactions with only two of the five hemocyanin components. The functional differences between the hemocyanin components may provide Limulus with a valuable respiratory flexibility in its interaction with the environment. The kinetics of oxygen combination and dissociation for the various hemocyanin preparations show that variations in the rate of oxygen dissociation are primarily responsible for the observed differences in oxygen affinity. The rate of oxygen dissociation varies 20-fold under conditions where the apparent rate of oxygen combination shows less than a 2-fold variation. Cooperative interactions in the untreated hemocyanin are most obvious in the "off" reaction, which increases in rate as successive oxygen molecules are released. PMID- 4210211 TI - Homology between bakers' yeast cytochrome b2 and liver microsomal cytochrome b5. AB - The amino-acid sequence of the hemebinding region of bakers' yeast cytochrome b(2) [L-(+)-lactate dehydrogenase, EC 1.1.2.3] has been determined. It shows a strong similarity with the sequence of microsomal cytochrome b(5), and appears to be compatible with the same kind of peptide-chain folding, in agreement with data obtained previously by various physiochemical methods. The comparison shows that the fifth and sixth heme ligands must be histidine residues, thus substantiating previous conclusions drawn in particular from photooxidation experiments and nuclear magnetic resonance studies. The data reported in this paper suggest a common origin for the two proteins. Implications for their biochemical evolution are presented. PMID- 4210213 TI - Radiology of small intestinal bleeding. PMID- 4210215 TI - The effects of testosterone on the sexual skin and genitalia of the male talapoin monkey. PMID- 4210214 TI - Myonecrosis in chronic experimental vasospasm. PMID- 4210217 TI - Proceedings: Electrical responses of the limbic regions to exogenous testosterone and stimulation of the genital regions. PMID- 4210216 TI - Degradation of immunoglobulins by secretions of human reproductive tracts. PMID- 4210218 TI - Need for improved plant proteins in world nutrition. PMID- 4210219 TI - [Valve of the detection of Australia antigen in blood donors]. PMID- 4210221 TI - The first two electron linear accelerators in South Africa. PMID- 4210222 TI - Proplast in cavity obliteration and soft tissue augmentation. PMID- 4210220 TI - Etiology of tuberculosis cutis in Jakarta. PMID- 4210224 TI - Influence of biological criteria on the magnitude of damage induced by gamma-rays and gamma-irradiated medium. PMID- 4210223 TI - Studies on physiology and biochemistry of mammalian epididymis: Histology, enzyme and electrolyte composition of epididymis--a comparative study. PMID- 4210225 TI - Genetic effects induced in Drosophila melanogaster cultured on irradiated glucose medium. PMID- 4210226 TI - Induction of mutations by thioridazine hydrochloride, an active ingredient of Mellaril. PMID- 4210228 TI - Detection of preformed enterotoxins of staphylococci in dairy products employing serological method. PMID- 4210229 TI - Influence of external factors on extracellular amino acid accumulation by Bacillus megaterium strain C II 19. PMID- 4210227 TI - Fermentative production of alpha-amylase by Aspergillus flavus. PMID- 4210230 TI - Australia antigen in chronic liver diseases. PMID- 4210232 TI - [Fabry's disease. Ultrastructural study of the cutaneous lesions]. PMID- 4210231 TI - [Vascular network in the syncytio-capillary membrane of the placenta]. PMID- 4210233 TI - [Intravenous anti-D immunoglobulins. (Prevention of anti-Rh immunization in France)]. PMID- 4210234 TI - Prevention of Rh immunization in Germany. PMID- 4210235 TI - Preliminary results of Rh-prophylaxis during pregnancy. PMID- 4210236 TI - [Prevention of isoimmunization Rh in Italy]. PMID- 4210237 TI - Fetal electrocardiographic evaluation of Rh-immunized pregnancies. Preliminary results by a new averaging technique. PMID- 4210240 TI - [Exsanguination intrauterine transfusion]. PMID- 4210238 TI - [Prognosis of neonatal non-immunologic hyperbilirubinemias]. PMID- 4210239 TI - [Feto-placental anasarca]. PMID- 4210241 TI - [Assistance to the premature infant with Rh hemolytic disease]. PMID- 4210245 TI - Viruses and the etiology of diabetes. PMID- 4210242 TI - [Methods for studying hemolytic disease of the newborn due to Rh and their standardization: hematology]. PMID- 4210244 TI - [Physiopathology of fever and mechanism of action of antipyretics]. PMID- 4210243 TI - Gonadotropins and their antibodies. PMID- 4210247 TI - Firing patterns of hypothalamic supraoptic neurons during water deprivation in monkeys. AB - Water deprivation in monkeys caused an acceleration of action potential firing of supraoptic neurons, but not of neurons located 2 to 3 millimeters above the hypothalamic supraoptic nucleus. Whereas in the normally hydrated animal only 12 percent of the neuroendocrine cells discharged periodically, the proportion of these periodic bursters increased markedly with increasing plasma osmolarity. This finding suggests that such periodically firing supraoptic neurons are those engaged in active neurohypophyseal hormone secretion. PMID- 4210246 TI - Morphologic changes of uterine wall following intra-amniotic injection of hypertonic saline in the rhesus monkey. PMID- 4210252 TI - Trace analysis of organic compounds. PMID- 4210248 TI - Intrathoracic meningocele associated with multiple neurofibromatosis: a rare cause of mediastinal tumour. PMID- 4210251 TI - [Relationship between the structure and antibacterial activity of aryl thioamides. V. Synthesis and in vitro tuberculostatic activity of 2-alkylthio benzothiamides and 2-alkylthio-phenyl-vinylethionamides]. PMID- 4210249 TI - Irreversible binding of ethynyl-estradiol metabolites to protein and nucleic acids as catalyzed by rat liver microsomes and mushroom tyrosinase. PMID- 4210253 TI - The sulfonamide-aminosulfone rearrangement: a rearrangement induced anionically, cationically, and thermally. PMID- 4210256 TI - The continuing problem of sepsis-following enzymatic debridement of burns. PMID- 4210254 TI - The pigments of reddish hair and feathers. PMID- 4210258 TI - [Left bundle-branch blocks with marked left axis deviation of the QRS axis]. PMID- 4210255 TI - [Quantitative determination of the immunoglobulins IgG, IgA and IgM]. PMID- 4210257 TI - Stroke: early portents of functional recovery in Black patients. PMID- 4210259 TI - [Ventricular-wall aneurysm and Dressler's syndrome]. PMID- 4210261 TI - [Obstructive cardiomyopathy and Friedreich's disease]. PMID- 4210262 TI - [Amplitude and power spectra of the electrical vibrations of the heart. Spectra of the normal heart]. PMID- 4210260 TI - [The heart in acromegaly. Haemodynamic study]. PMID- 4210264 TI - [The postoperative re-equilibration of infants weighing more than 10 Kg]. PMID- 4210266 TI - An unusual tumour of the neck and superior mediastinum. PMID- 4210265 TI - Mass transfer of Co2 across membranes: facilitation in the presence of bicarbonate ion and the enzyme carbonic anhydrase. PMID- 4210263 TI - [Incarceration of aortic bacterial endocarditis vegetations into the coronary ostia. Apropos of 3 cases]. PMID- 4210267 TI - [Evaluation of Laurosept for the isolation of tubercle bacilli from diagnostic materials]. PMID- 4210270 TI - Single radial diffusion using catalase antibody as screening method of hypocatalasemia. PMID- 4210268 TI - [Problem of repeated relapsing nodular goiter]. PMID- 4210269 TI - [Modern data on the mutagenic and cytotoxic properties of irradiated food substances and products (a review of the literature)]. PMID- 4210271 TI - The effects of protein calorie malnutrition on immune competence of the surgical patient. PMID- 4210272 TI - Evaluation of mitochondrial function in the ischemic rat liver. PMID- 4210273 TI - Epithelial cell phagocytosis of Listeria monocytogenes in the conjunctiva. PMID- 4210274 TI - Primary reconstruction of depressed frontal skull fractures including those involving the sinus, orbit, and cribriform plate. PMID- 4210275 TI - Epilepsy after monmissile depressed skull fracture. PMID- 4210276 TI - Pyelonephritis. 18. Effect of treatment on the pathology of enterococcal pyelonephritis in the rat. AB - The effect of antimicrobial therapy on the histopathologic progression of experimental hematogenous pyelonephritis induced in rats by Streptococcus faecalis was studied. Treatment sufficient to render the renal parenchyma sterile strikingly decreased the incidence and severity of calyceal lesions, delayed the progression of papillary lesions but had little effect on the severity of cortical interstitial and tubular alterations. L-forms could not be demonstrated to participate in the pathogenesis of these lesions. Kanamycin had an independent nephrotoxic effect which complicated interpretation of the effect of therapy in animals receiving this agent. PMID- 4210279 TI - The secretory immunologic system of fowl. IV. Serum and salivary immunoglobulins in normal, agammaglobulinemic and dysgammaglobulinemic chickens. PMID- 4210278 TI - Animal model: Oxygen toxicity in nonhuman primates. PMID- 4210277 TI - Liver cell differentiation in a chemically defined medium. Morphologic and enzymatic comparisons of in utero rat liver and liver rudiment grown in organ culture. AB - The liver diverticulum of the 11-day rat embryo has been grown in a chemically defined medium. Cytodifferentiation and enzymatic activities in the organ culture have been compared with those in the embryonic liver developing in vivo. In the absence of hormone and tissue extracts the liver diverticulum grew and differentiated extensively in the synthetic medium. The appearance and development of cytoplasmic organelles (rough and smooth endoplasmic reticulum, Golgi complex and glycogen particles) and enzymatic activity (glycogen synthetase) in both the embryonic liver and the comparable organ-cultured liver diverticulum were parallel. PMID- 4210280 TI - Precipitation of serum and tissue proteins by phytohaemagglutinin (PHA) in breast cancer patients. PMID- 4210281 TI - Sexual dimorphism in the secondary immune response of the Syrian hamster. PMID- 4210284 TI - Rough membranes in Schizosaccharomyces pombe protoplasts. PMID- 4210282 TI - Reciprocal induction of cell division by cells of complementary mating types in Tetrahymena. PMID- 4210283 TI - The rate of uptake of 3H-actinomycin during the cell cycle of Tetrahymena. PMID- 4210285 TI - Unit discharges in the mediodorsal nucleus of the squirrel monkey evoked by electrical stimulation of the olfactory bulb. PMID- 4210286 TI - Electroencephalographic changes induced by cerebellar stimulation in freely moving primates. PMID- 4210287 TI - Cortical cell discharge patterns in anticipation of a trained movement. PMID- 4210289 TI - Changes in complement activity, serum proteins, and prothrombin time in guinea pigs fed rubratoxin alone or in combination with aflatoxin. PMID- 4210288 TI - [Kinetic study of serum alpha-1 fetoprotein in the newborn]. PMID- 4210291 TI - [EEG findings in normal children and in epileptics of age groups 7-15 years (analysis of hospital cases of 1300 children)]. PMID- 4210290 TI - Pathogenesis of Trypanosoma equiperdum in deer mice (Peromyscus maniculatus). PMID- 4210293 TI - Acute transmural myocardial infarction. Its occurrence in a young man without demonstrable coronary artery disease. PMID- 4210292 TI - [An unusual polyfibromatosis (atypical Dupuytren-Ledderhose disease, fibroma of the mouth mucosa, "epilepsy")]. PMID- 4210294 TI - Management of childhood asthma in Britain. PMID- 4210295 TI - Familial hepatic cirrhosis in infants associated with alpha1-antitrypsin SZ phenotype. PMID- 4210296 TI - X-linked B lymphocyte deficiency. I. Panhypo-gamma-globulinemia and dys-gamma globulinemia in siblings. PMID- 4210299 TI - Allozyme variation in the fruit flies Dacus tryoni and Dacus neohumeralis (Tephritidae). PMID- 4210297 TI - Comparative pharmacokinetics of amikacin and kanamycin. PMID- 4210298 TI - Bioequivalency of generic and brand-named chlorpromazine. PMID- 4210300 TI - Phenol oxidase activity and the lozenge locus of Drosophila melanogaster. PMID- 4210303 TI - Assay of serum folate: difference in serum folate values obtained by L. casei bioassay and competitive protein-binding assay. PMID- 4210301 TI - Adh-n5: a temperature-sensitive mutant at the Adh locus in Drosophila. PMID- 4210302 TI - Two new antisickling agents and the use of amino acid salts. PMID- 4210304 TI - A simple procedure for the isolation of IgG anti-nuclear antibodies from human serum. PMID- 4210306 TI - [Postoperative parenteral hyperalimentation and wound healing in oncological surgery (author's transl)]. PMID- 4210305 TI - A new colorimetric method for the determination of glutathione in erythrocytes. PMID- 4210307 TI - Occupational allergy to animal dander and sera. PMID- 4210311 TI - [Demodicosis in sheep]. PMID- 4210308 TI - Synthesis of free ATP from membrane-bound ATP in chromatophores of Rhodospirillum rubrum. PMID- 4210309 TI - Polarized light spectroscopy of photosynthetic membranes in magneto-oriented whole cells and chloroplasts. Fluorescence and dichroism. PMID- 4210312 TI - [Dynamics of the enterohelminthic polyparazitization in cattle under tropical conditions]. PMID- 4210310 TI - [Effectiveness of various concentrations of trichlorfon in administration of the preparations Hypocid, Neohypodermin and Gipodermin-chlorofos against hypodermosis in cattle]. PMID- 4210313 TI - [Necrotizing nephrosis with granuloma and multiple cystopapillary adenomas during a mass outbreak of the disease in the American char and the rainbow trout]. PMID- 4210314 TI - [Furunculosis of the brook trouts]. PMID- 4210318 TI - Proteins in bull rete testis and cauda epididymidia plasma. PMID- 4210315 TI - [Plesiomonas shigelloides in rainbow troup septicemia]. PMID- 4210317 TI - Effects of selective frontal lobe lesions on response to separation in adolescent rhesus monkeys. PMID- 4210319 TI - The development and diversification of Precambrian life. PMID- 4210316 TI - Neuronal mechanism of the disynaptic inhibition evoked in primate spinal motoneurones from the corticospinal tract. PMID- 4210321 TI - Induction of mitotic gene conversion in Saccharomyces cerevisiae by N-nitrosated pesticides. PMID- 4210320 TI - Coacervate systems and origin of life. PMID- 4210322 TI - A cytogenetic analysis of x-ray induced "visible" mutations at the yellow locus of Drosophila melanogaster. PMID- 4210323 TI - The effect of caffeine on repair systems in oocytes of Drosophila melanogaster. I. PMID- 4210324 TI - [Physiology of genetic competence in bacteria]. PMID- 4210325 TI - ATP-dependent deoxyribonuclease in Bacillus subtilis and a mutant deficient in this activity. PMID- 4210329 TI - [Anatomo-clinical classification of hemorrhagic pathology of the small intestine]. PMID- 4210327 TI - Differences in the mother-infant relations of squirrel monkeys housed in social and restricted environments. PMID- 4210326 TI - Modification of radiation-induced genetic damage in Drosophila melanogaster male germ cells with nucleic acid precursors. 3. Effects on the premeiotic cells. PMID- 4210328 TI - Social preferences of mother and infant squirrel monkeys following different rearing experiences. PMID- 4210330 TI - Virulence of Pseudomonas aeruginosa and spontaneous spread of pseudomonas pneumonia in a mink ranch. AB - Comparative studies on the virulence of two strains of Pseudomonas aeruginosa isolated from otic pus and mink pneumonic lesion, respectively, were made by means of intranasal inoculation in mink. The minimal lethal dose of the former (strain NC-5, highly virulent for mice) was 10(10), and that of the latter (strain No. 5, moderately virulent for mice) was 5.5 x 10(6). By planting droplets of P. aeruginosa suspension on the mink in the wire cages, an enzootic lethal pneumonia was brought about in a ranch. This disease spread to the neighboring 12 mink in turn, in one direction, with new cases occurring every day or every other day for 13 days. PMID- 4210331 TI - Mycobacterial components responsible for the induction of a chronic immunological inflammatory response in rabbit lungs. AB - Fractions of the tubercle bacillus were examined for their capacity to produce an allergic pulmonary granulomatous response in rabbits. We found that emulsions containing old tuberculin and even old tuberculin alone in an emulsion could induce a pulmonary inflammatory reaction comparable in intensity to that produced with killed BCG. Emulsions lacking old tuberculin failed to produce an allergic pulmonary inflammatory response. The significance of these results in relation to immunological and nonimmunological chronic inflammation is discussed. PMID- 4210333 TI - T cell dependence of macrophage activation and mobilization during infection with Mycobacterium tuberculosis. AB - Mice made T cell-deficient as adults by thymectomy and lethal irradiation, and infected with Mycobacterium tuberculosis, showed a greatly reduced capacity to develop nonspecific resistance to challenge with a heterologous bacterium. The capacity to develop nonspecific resistance was restored, however, by an infusion of syngeneic thymocytes. Evidence was presented which showed that the capacity of mycobacteria-infected mice to resist a lethal challenge with a heterologous organism rested on the capacity of macrophages existing at the time of challenge to reduce the number of challenge organisms to a sublethal level within 8 h. This antibacterial activity of macrophages was substantially reduced in T cell deficient mice but could be restored by an infusion of syngeneic thymocytes. It was concluded that T cell-deficient mice have a reduced capacity to mobilize and activate macrophages because of their reduced capacity to respond immunologically to antigens of M. tuberculosis. PMID- 4210332 TI - Phagocytosis of live versus heat-killed bacteria by human polymorphonuclear leukocytes. AB - Heat-killed Pseudomonas aeruginosa are phagocytized much more slowly by human polymorphonuclear leukocytes than are the live organisms. The post-phagocytic increase in hexose monophosphate shunt activity (HMS) parallels the ingestion of the bacteria. The addition of serum to the live organisms causes a marked increase in both ingestion and cellular HMS activity; serum actually causes an inhibition of both uptake and HMS activity when added to the heat-killed organisms. Differences in postphagocytic HMS activity between live and heat killed organisms were observed with three different species of bacteria, indicating that the phenomenon is not restricted to P. aeruginosa. These data emphasize that the influence of the particle on the phagocytic process is considerable. PMID- 4210336 TI - Insect immunity. I. Characteristics of an inducible cell-free antibacterial reaction in hemolymph of Samia cynthia pupae. AB - Pupae of the silk moth, Samia cynthia, were found to contain an inducible antibacterial activity in their hemolymph. This immunity response was provoked by primary infections with either Escherichia coli K-12 or Enterobacter cloacae. In both cases the antibacterial activity was directed chiefly towards E. coli. During standard conditions, 1% of hemolymph could kill 10(3) to 10(4) viable E. coli, strain D31, within 5 min. A lower level of antibacterial activity was induced by injections of a sterile salt solution. The killing of strain D31 followed single-hit kinetics, and increasing rate constants were obtained for increasing amounts of hemolymph. The reaction was sensitive to pretreatment with trypsin and it was protected by reducing agents. The activity was inhibited by microgram quantities of lipopolysaccharide (LPS) prepared from certain LPS mutants of E. coli K-12. A comparison of the susceptibility showed that "heptose less" LPS mutants were more sensitive to killing than other strains. During standard conditions hemolymph will lyse both E. coli and Micrococcus lysodeikticus. Lysis of E. coli followed a multi-hit kinetics and it was inhibited by LPS, whereas lysis of M. lysodeikticus was unaffected by LPS. Hemolymph was fractionated on Sephadex G-200, and the lytic activities were recovered in partly overlapping peaks. Reconstitution with pooled fractions gave synergistic effects with the killing assay. PMID- 4210334 TI - Immunity to Candida albicans induced by Listeria monocytogenes. AB - Immunity to Candida albicans was studied in Swiss-Webster white female mice. Lethal and sublethal infections with C. albicans did not enhance immunity to a subsequent Listeria monocytogenes challenge. Mice sensitized to L. monocytogenes and then challenged with C. albicans intravenously were able to reduce the population of C. albicans in their kidneys after being boosted (rechallenged) with L. monocytogenes. However, the acquired cellular immunity so induced was very short-lived. Both C. albicans-sensitized and nonsensitized control mice showed an immediate-type and delayed-type skin test response to the cell wall antigen(s) of C. albicans but not to the cytoplasmic antigen(s). There did not appear to be any correlation between increase in skin test response and progression of the candida infection in mice. PMID- 4210335 TI - Purification and antigenicity of an M-like protein of Streptococcus equi. AB - A cell wall component of Streptococcus equi analogous to the M protein of group A streptococci has been identified and purified. A highly purified product has been obtained from cells by hot acid extraction, followed by acid precipitation, ammonium sulfate fractionation, and column chromatography. This product reacts with S. equi antiserum. The existence of this fraction in S. equi has been confirmed by the failure of trypsin-treated cells and their extracts to remove the long-chaining capacity of S. equi antiserum. The antigenicity of this M-like protein when incorporated in adjuvant has been assessed in rabbits and horses. In the rabbit, multiple doses of as low as 10 mug resulted in the production of serum capable of inducing long-chain formation and opsonizing and mouse protective antibody. Two doses of 100 mug elicited similar responses. The bactericidal capacity of this serum could be eliminated by absorption with whole S. equi cells or their extracts, but not by absorption with trypsin-treated cells or extracts therefrom. Horses vaccinated 15 months previously with a whole-cell killed vaccine and given 200 mug of the purified protein intramuscularly showed evidence of an anamnestic response to the antigen. PMID- 4210337 TI - Slime of Pseudomonas aeruginosa: in vivo production. AB - Indirect hemagglutination inhibition tests were employed to detect slime in concentrations as low as 1 mug/ml. Increasing concentrations of slime resulted in proportionately greater inhibition of hemagglutination. Peritoneal aspirates and plasma of mice injected with slime were shown to exhibit the inhibitory activity of slime. The rapid dissemination of slime into the peripheral circulation was also indicated by the hemagglutination of mouse erythrocytes by specific anti slime serum. By similar methods, the inhibitory activity of slime was also detected in peritoneal aspirates and plasma of mice infected with lethal doses of viable Pseudomonas aeruginosa. Furthermore, the inhibitory activity was found to increase with time after viable cell infection, whereas such increases were not detected after the injection of heat-killed organisms. Ferritin-labeled slime antibodies were found to completely surround cells of Pseudomonas aeruginosa obtained from the peritoneal cavity of mice 5 h postinfection. PMID- 4210338 TI - Fish rhabdovirus replication in non-piscine cell culture: new system for the study of rhabdovirus-cell interaction in which the virus and cell have different temperature optima. AB - The replication of three rhabdoviruses associated with diseases of fish has been demonstrated in cells of continuously cultivated non-piscine cell lines. Spring viremia of carp (SVC) virus and the salmonid fish viruses, Egtved and infectious hematopoietic necrosis virus, all replicated in mammalian WI-38 (human diploid cell strain) and BHK/21 cells and in cells of one or more reptilian cell lines at the temperatures commonly used to propagate these viruses in fish cells. The infections were cytopathic: SVC virus plaque assays may be performed in several types of mammalian cell culture. "Autointerference" apparently mediated by abortive "T" particle formation was observed during serial nondiluted passages of SVC virus in BHK/21 and TH1 cells, but not in RTG-2 or WI-38 cells. Optimal temperatures for replication of SVC and Egtved viruses in BHK/21 cells were identical to those determined in poikilothermic vertebrate cell cultures. However, these viruses replicated relatively more efficiently at suboptimal temperatures in "cold-blooded" vertebrate cells than in the hamster cells. Studies of [(3)H]uridine incorporation into uninfected BHK/21 cells incubated at different temperatures revealed that [(3)H]uridine uptake is sharply reduced at temperatures below 24.5 C. Growth curve studies of SVC virus in BHK/21 cells incubated at 23 C revealed that a clear-cut large excess of virus-induced [(3)H]uridine incorporation could be demonstrated in the absence of actinomycin D. Actinomycin D treatment (1 mug/ml) led to efficient inhibition of control cell [(3)H]uridine uptake, but also markedly reduced the total counts per minute of virus-induced [(3)H]uridine uptake, without depressing the yield of released infectious virus. Actinomycin D added to SVC virus-infected BHK/21 cell cultures at concentrations as low as 0.01 mug/ml caused a significant decrease in the level of virus-induced [(3)H]uridine uptake, despite the fact that this concentration is insufficient to efficiently suppress "background" cellular [(3)H]uridine incorporation. PMID- 4210339 TI - Ultrastructural studies of Rickettsia prowazeki from louse midgut cells to feces: search for "dormant" forms. AB - An electron microscope study of infected human louse gut cells and feces was made to determine whether a valid correlation exists between the increased resistance of Rickettsia prowazeki (in the louse feces) to adverse environmental influences and changes in the organism which might be reflected in its ultrastructure. Upon fine structural examination of this intracellular parasite as it passed from the louse midgut cell to the feces, it was apparent that no such morphological changes had occurred. PMID- 4210340 TI - Immunodiffusion analysis of membranes of Thermoplasma acidophilum. AB - Isolates of Thermoplasma acidophilum were divided into serological groups based on immunodiffusion studies of solubilized-membrane preparations. PMID- 4210341 TI - Interferon induction in mice by lipopolysaccharide from Brucella abortus. AB - Endotoxin or lipopolysaccharide isolated from Brucella abortus (strain 456) produced a typical endotoxin-type interferon response in mice with peak levels of the inhibitor occurring 2 h after intravenous injection of the stimuli. Brucella lipopolysaccharide was a much less effective interferon stimulus than the lipopolysaccharide isolated from Salmonella typhimurium (strain LT-2). PMID- 4210342 TI - [Lipemia retinalis in idiopathic hyperlipemia (author's transl)]. PMID- 4210346 TI - Observations on the reproducibility of the bromelised test cell anti-D assay using the auto-analyser. PMID- 4210345 TI - Isolation and characterization of ribosomes from Streptomyces griseus spores. PMID- 4210343 TI - [Influence of metabolic inhibitors on rosette-forming human lymphocytes in vitro]. PMID- 4210344 TI - Pectinase activities in some fungi. PMID- 4210349 TI - Bone growth in protein calorie malnutrition. PMID- 4210348 TI - Blood-group-like substances in some marine invertebrates. I. Blood-group A reactive substances in the ascidian Phallusia mammilata (Cuvier) and in the lancelet Amphioxus (branchiostoma) lanceolatus (Pallas). PMID- 4210347 TI - Efficiency of anti-D IgG prevention after induced abortion. PMID- 4210350 TI - Schonlein-Henoch syndrome in a case of protein calorie malnutrition (case report). PMID- 4210351 TI - Two years study on sugar intolerance in Indonesian children. PMID- 4210352 TI - [Electric and clinical aspects of petit mal epilepsy based on telemetric studies]. PMID- 4210354 TI - Blepharmone: a conjugation-inducing glycoprotein in the ciliate blepharisma. AB - Gamone 1 of Blepharisma intermedium was isolated, identified as a slightly basic glycoprotein (mizoleclular weight, 2 x 10(5)), and designated as blepharmnone. At the concentration of 6 x 10(-8) milligram per milliliter, it specifically transforms matinig type 2 cells, so that they can conjugate in about 2 hours. PMID- 4210353 TI - Protein-calorie malnutrition in children and its relation to psychological development and behavior. PMID- 4210355 TI - Initiation of the transcription of phi29 DNA by Bacillus subtilis RNA polymerase. PMID- 4210357 TI - Immunochemical studies on duck (Anas platyrhynchos) ovotransferrin-isolation, isoelectric fractionation and antigen-antibody reaction. PMID- 4210356 TI - Effect of an epipodophyllotoxin derivative (VP 16-213) on macromolecular synthesis and mitosis in mastocytoma cells in vitro. PMID- 4210358 TI - Metabolic clearance rate of progesterone during lactation in the Rhesus monkey. PMID- 4210360 TI - Human liver aminopeptidase. Role of metal ions in mechanism of action. PMID- 4210359 TI - Evidence for multiple polypeptide chains in the membrane protein spectrin. PMID- 4210361 TI - Identity of the Fc fragments of pathological and normal human immunoglobulin M. PMID- 4210362 TI - Effect of reaction conditions on the reassociation of divergent deoxyribonucleic acid sequences. PMID- 4210363 TI - Three-segment RNA genome of Lumbo virus (Bunyavirus). PMID- 4210364 TI - Localized humoral immunity with particular reference to ruminants. PMID- 4210365 TI - A new acidic protease in human seminal plasma. PMID- 4210366 TI - The reassociation of ribosomal subunits from the muscle of normal and diabetic animals. PMID- 4210367 TI - Dissociation of skeletal muscle ribosomes from normal and diabetic animals by initiation factors EIF-3. PMID- 4210368 TI - Studies on anti-poly(adenosine diphosphate ribose) antibody. PMID- 4210369 TI - [Quantitative determination of urinary excretion of mycobacteriae in patients with urogenital tuberculosis]. PMID- 4210371 TI - [Evaluation of carbenicillin therapy (author's transl)]. PMID- 4210370 TI - [Letter: Mixed IgM-IgG cryoglobulinemia. A case in a patient with Waldenstrom's macroglobulinemia]. PMID- 4210373 TI - Aflatoxins in mutants of Aspergillus flavus. PMID- 4210372 TI - Skin disinfection with ethanol, without and with additives. PMID- 4210376 TI - Letter: Volumes of injections in mice. PMID- 4210378 TI - EM autoradiographic studies on polytene nuclei of Drosophila melanogaster. II. Organization and transcriptive activity of the chromocentre. PMID- 4210374 TI - Use of syringaldazine for detection of laccase in sporophores of wood rotting fungi. PMID- 4210375 TI - A radioisotope study of the vascular response to sagittal split osteotomy of the mandibular ramus. PMID- 4210377 TI - Studies on cell adhesion in tissue culture. XV. Some effects of cycloheximide on cell detachment. PMID- 4210379 TI - Disinfecting hydrotherapy equipment. PMID- 4210380 TI - Hemispheric differences in the discrimination of line orientation. PMID- 4210381 TI - The effects of posterior cortical lesions on eye orientation during visual discrimination by monkeys. PMID- 4210382 TI - Cerebral dominance in monkeys? PMID- 4210384 TI - Detection of IgM heterogeneity dependent on the support medium of immunoelectrophoresis. PMID- 4210383 TI - Plasma cell dyscrasias (except myeloma). PMID- 4210385 TI - An assay of bilirubin UDP-glucuronyl transferase on needle-biopsies applied to Gilbert's syndrome. PMID- 4210386 TI - An assessment of the suitability of bromocresol green for the determination of serum albumin. PMID- 4210388 TI - [Structural characterization of the C-reactive protein]. PMID- 4210387 TI - Recovery from malnutrition: food preference and neophobia. PMID- 4210389 TI - [The cerebrospinal fluid in cerebrovascular accidents: value of electrophoresis and cytomorphological study by the sedimentation method]. PMID- 4210391 TI - Production of cycloheximide by Streptomyces sp. PMID- 4210392 TI - Serological studies on toxoplasmosis in patients with typhoid fever. PMID- 4210390 TI - Relations of HL-A and Rh systems to immune reactivity. Joint report of the results of 'HL-A and immune response' workshop, Budapest 1972. PMID- 4210394 TI - Practical application of a simplified vitamin B12 radioassay. PMID- 4210393 TI - The histaminase activity of guinea-pig's plasma during experimental inflammation. II. Some properties of the enzyme. PMID- 4210395 TI - Total nutrition by peripheral vein--the lipid system. AB - A means for providing total nutrition is described in which 10% soybean oil eggyolk phosphatide-glycerol emulsion (Intralipid) and a solution of 5% dextrose in 5% protein hydrolysate are given simultaneously into a peripheral vein, utilizing two giving sets united by a Y-connector at the needle. No ketonuria occurred, and there were no side effects from the lipid emulsion. Advantages of this system include absence of significant peripheral phlebitis, avoidance of the hazards of caval catheters, and absence of the complications of hypertonic solutions. Disadvantages include restricted forearm movement and frequent regulation of flow-rates.This system was used in 23 patients for periods of 4 to 78 days (mean 16.3 days). Weight gain and healing occurred, and all survived but one patient who died of myocardial infarction following successful surgical closure of an enterocolocutaneous fistula. The lipid system adds another method to the measures available for the management of major nutritional problems. PMID- 4210396 TI - Coronary hypertonia and angina. AB - Coronary hypertonia was observed in a patient with unstable angina. It was possible on one occasion to reproduce the clinical picture, electrocardiographic changes, lactate production and coronary hypertonia by means of atrial pacing. He had a normal left coronary arteriogram when the diffuse spasm was relieved by nitroglycerin. Therefore hypertonia (or spasm) of the left coronary artery was believed to be the cause of his variant angina with subendocardial ischemia. PMID- 4210400 TI - Bacterial growth inhibition by amniotic fluid. I. In vitro evidence for bacterial growth-inhibiting activity. PMID- 4210398 TI - Energy requirement in regenerative and atrophic processes of the liver in man and other mammals. PMID- 4210399 TI - Myocardial viability after transient ischemia in primates. PMID- 4210401 TI - Maternal mumps infection during gestation: observations on the progeny. PMID- 4210403 TI - The ganglion on the internal laryngeal nerve. PMID- 4210397 TI - A comparison of nutritional gains resulting from intravenous and enteral feeding. PMID- 4210402 TI - Congenital lesions of the inner ear, demonstrated by tomography. PMID- 4210404 TI - Cochlear electrical activity in noise-induced hearing lossmbehavioral and electrophysiological studies in primates. PMID- 4210405 TI - Transport of lead 203 and calcium 47 from mother to offspring. PMID- 4210406 TI - Organized labor and the prepaid group practice movement. PMID- 4210407 TI - Response of the left ventricle to nitroglycerin in patients with and without mitral regurgitation. PMID- 4210408 TI - [The retromamillary arterial syndrome (author's transl)]. PMID- 4210409 TI - [Representation of Trematodes species, suborder Paraphistomata in Cuba]. PMID- 4210410 TI - [Epizootic dermatophytosis in large-scale breeding of guinea pigs]. PMID- 4210411 TI - [Prevention of RH sensitization in Switzerland]. PMID- 4210412 TI - Prevention of Rh-immunization in Sweden. PMID- 4210413 TI - Management of pregnancy complicated by Rh-immunization. Review with respect to own investigations and results. PMID- 4210414 TI - [Perinatal mortality of neonatal hemolytic disease due to Rh. Report on cases at the O.G. Mangiagalli Institute in Milan]. PMID- 4210415 TI - [Serologic methods for study of hemolytic disease of the newborn and their standardization]. PMID- 4210417 TI - [The role of the umbilical vein in postoperative care]. PMID- 4210416 TI - On the control of gonadotropin secretion in the rhesus monkey. PMID- 4210418 TI - [Determination of thyro-binding globulin (TBG) and of thyro-binding prealbumin(TBPA) with in vitro radioassay]. PMID- 4210419 TI - [Triple valve replacements. Immediate risks and long-term prognosis]. PMID- 4210420 TI - [Hemodynamic effects of conversion to sinus rhythm in isolated atrial fibrillation]. PMID- 4210422 TI - [Dysfunction of valvular prostheses caused by fibrosis]. PMID- 4210421 TI - [Sequential angiocardiographic scanning. Morphological data]. PMID- 4210423 TI - [Pulmonary artery aneurysms (apropos of a case of aneurysm of the pulmonary artery trunk and its left branch)]. PMID- 4210424 TI - Elastase of Pseudomonas aeruginosa: inactivation of complement components and complement-derived chemotactic and phagocytic factors. AB - A purified elastase from Pseudomonas aeruginosa was highly destructive for fluid phase and cell-bound C1 and C3 and fluid-phase C5, C8, and C9. Inactivation of C4, C2, C6, and C7 by the enzyme varied from 0 to 67%. Low concentrations of elastase generated, then inactivated, a chemotactic factor from human C5 but not from C3. Higher enzyme concentrations inactivated the C5 chemotactic activity at a faster rate. Elastase treatment of sensitized pseudomonads containing cell bound C3 reduced the phagocytic indexes of polymorphonuclear leukocytes. The data support the proposed chemopathogenic role of the elastase in generation of the characteristic non-inflammatory Pseudomonas vasculitis. PMID- 4210425 TI - IgG levels in amniotic fluid. PMID- 4210426 TI - Escherichia coli gene transfer to unrelated bacteria by a histidine operon--RP1 drug resistance plasmic complex. PMID- 4210427 TI - Complement and antibody in self-agglutinating human semen. PMID- 4210428 TI - "Lower" gastrointestinal tract hemorrhage: new concepts based on arteriography. PMID- 4210429 TI - [Chromosomal studies in correlation with other biologic constants in neoplasms treated by chemotherapy]. PMID- 4210430 TI - Management of juvenile laryngeal papilloma: further observations. PMID- 4210431 TI - Adaptive responses to total intravenous feeding. PMID- 4210433 TI - Multiple IgM autoantibodies in a nonhuman primate. PMID- 4210432 TI - Neurophysiological effects of dorsal column stimulation in man and monkey. PMID- 4210434 TI - The inactivator of the first component of human complement (C1INA). The complex formation with the activated first component of human complement (C1) or with its subcomponents. PMID- 4210435 TI - Structure and biochemistry of phloem-proteins isolated from Cucurbita maxima. PMID- 4210436 TI - Neisseria meningitidis serogroup Y: incidence and description of clinical illness. PMID- 4210437 TI - Cromolyn sodium therapy for chronic perennial asthma. A double-blind study of 40 children. PMID- 4210438 TI - Frequency of the ocular choroid blush during arteriography. PMID- 4210439 TI - Feather keratin--analysis of subunit heterogeneity. PMID- 4210441 TI - The Lansing effect revisited. I. Life-span. PMID- 4210440 TI - [Juvenile GM2 gangliosidosis with altered substrate specificity of hexosaminidase A (author's transl)]. PMID- 4210442 TI - Pulmonary tuberculosis in free-living lechwe antelope in Zambia. PMID- 4210443 TI - A pathogenic theilerial syndrome of cattle in the Narok District of Kenya. I. Transmission studies. PMID- 4210444 TI - A pathogenic theilerial syndrome of cattle in the Narok District of Kenya. II. Serological studies. PMID- 4210445 TI - East Coast Fever: field challenge of cattle immunised against Theileria parva (Muguga). PMID- 4210446 TI - Sarcosporidiosis-a review. PMID- 4210447 TI - Effects of nutritional state and of administration of glucose, glibenclamide or diazoxide on the storage of amylase in mouse pancreas. PMID- 4210448 TI - [Incorporation of sulfate S35O4 in fibroblasts of patients suffering from type 3 mucopolysaccharidosis (type A and B)]. PMID- 4210450 TI - [Sandhoff's disease: clinical and genetic study of a French-Canadian child]. PMID- 4210449 TI - The severity of lactose intolerance in Indonesian children. PMID- 4210451 TI - [Studies on the isolation culture technique of tubercle bacilli applicable in remote areas. 2 (author's transl)]. PMID- 4210452 TI - [Management problems after massive bowel resection in a child (author's transl)]. PMID- 4210453 TI - Identification of Neisseria gonorrhoeae in synovial membrane by electron microscopy. PMID- 4210454 TI - Trends in disease caused by Neisseria meningitidis: 1972 and 1973. PMID- 4210455 TI - Computerized system for stimulus generation, control, behavioral data acquisition and summary for primate visual psychophysics. PMID- 4210456 TI - Protein deprivation in primates. 3. Cage activities and chain-pulling behavior of adult rhesus monkeys maintained on low-protein diets. PMID- 4210457 TI - Clozapine--a new antipsychotic agent. PMID- 4210458 TI - Clozapine--a potential antipsychotic agent without extrapyramidal manifestations. PMID- 4210459 TI - A double-blind comparison of once-a-day pimozide, trifluoperazine, and placebo in the maintenance care of chronic schizophrenic outpatients. PMID- 4210460 TI - Orgotein: a new anti-inflammatory metalloprotein drug: preliminary evaluation of clinical efficacy and safety in degenerative joint disease. PMID- 4210461 TI - Double-blind study of the analgesic effect of ethoheptazine-aspirin. PMID- 4210462 TI - A double-blind study to assess the efficacy of oral tilidine hydrochloride (W5759A)among a group of post-operative orthopedic and trauma patients. PMID- 4210463 TI - Controlled-release potassium supplementation. PMID- 4210464 TI - Gastrointestinal blood loss in patients receiving acetylsalicylic acid or diftalone, a new antiinflammatory drug: a comparative evaluation. PMID- 4210465 TI - Evaluation of corticosteroids intended for use as topical anti-inflammatory drugs. PMID- 4210466 TI - Immunopathological studies in patients with farmer's lung. PMID- 4210467 TI - Septicaemia and meningitis caused by Neisseria mucosa varietas heidelbergensis. PMID- 4210468 TI - The histaminase activity of guinea-pig's plasma during experimental inflammation. I. The enzyme activity. PMID- 4210469 TI - [Classification of hyperlipoproteinemia. I. Comparison of Fredrickson's classification with that of Thannhauser. Distribution principle of xanthomatosis]. PMID- 4210470 TI - Differentiation and medical importance of saccharolytic intestinal Bacteroides. PMID- 4210471 TI - Mycobacterial proficiency testing in the Quality Evaluation Programs of the College of American Pathologists, 1972. PMID- 4210472 TI - Plaque formation by mixed cultures of nonprimary plaque-forming microorganisms. PMID- 4210473 TI - Effects of tetracyclines on membranous bone growth and dentin apposition in young rhesus monkeys. PMID- 4210474 TI - Two-site model for human dental enamel dissolution in EDTA. PMID- 4210475 TI - Electromyography of the mandibular postural position in the rhesus monkey (Macaca mulatta). PMID- 4210476 TI - Pulmonary bacterial susceptibility in the burned rat. AB - An in vivo model system, using the burned rat as a model of altered host resistance, was developed and studied to investigate the lung's ability to handle an aerosolized bacterial insult of either P. aeruginosa or S. aureus. Rates of lung bacterial clearance were correlated with mortality, bacteriologic and histologic results. Susceptibility of the lung to sepsis was shown to be directly related to host resistance and was significantly increased following cutaneous thermal injury. Exposure of burned, non-seeded rats to a bacterial aerosol on day one post burn resulted in a mortality of 50% (P. aeruginosa) and 11.1% (S. aureus). This mortality clearly demonstrates an increased susceptibility at day one post burn. In contrast, this susceptibility gradually decreased with time; no mortality in the burned rat when exposed on day six post burn or in the normal, unburned rat. Histologic findings correlate well with the mortality results showing a gradually decreasing severity of pneumonitis if aerosol exposure was further delayed. Lung bacterial clearance studies revealed that the initial good response of the pulmonary defense mechanisms immediately following aerosol challenge are short-lived and that a marked increase in pulmonary bacterial susceptibility occurs as early as 24 hours following thermal injury. PMID- 4210477 TI - Pancreatic secretion in response to jejunal feeding of elemental diet. AB - The instillation of elemental diet into the proximal jejunum of dogs results in a brisk pancreatic secretory response, but the fluid is watery and "enzyme-poor." The administration of the caloric equivalent in a standard blenderized ward diet induces pancreatic enzyme secretion. Although elemental diet does not "rest" the pancreas, the failure of these preparations to stimulate pancreatic enzyme secretion gives them a theoretical advantage as a nutritional source in the convalescent phase of acute pancreatitis. PMID- 4210478 TI - A self control method for long term anticoagulation therapy. PMID- 4210479 TI - [The effects of antituberculosis chemotherapy in vitro under various conditions inadequate for the growth of tubercle bacilli. V. Incubating temperature and chemotherapeutic effects. 2 (author's transl)]. PMID- 4210480 TI - [Use of bone marrow smear in the diagnosis of leucosis in the Bohemian spotted cattle]. PMID- 4210481 TI - Studies in immunodermatology. V. Basement membrane and reticulin antigens in human sera. PMID- 4210482 TI - Development of antennal imaginal disks in Drosophila melanogaster by induced mosaicism. Experiments with strains y sn ++ and y sn ++; ssa. PMID- 4210483 TI - Antagonistic effects of glutamine and histamine on in vitro lysozyme activity. PMID- 4210484 TI - [Methods for the study of fetal erythroblastosis due to Rh and their standardization: amniotic fluid]. PMID- 4210485 TI - Instrumented PVP-augmented antiglobulin tests. I. Detection of allogeneic antibodies coating otherwise normal erythrocytes. PMID- 4210486 TI - Navajo jaundice: a variant of neonatal hyperbilirubinemia associated with breast feeding. PMID- 4210487 TI - Use of marrow-cancellous bone grafts in maxillary alveolar and palatal clefts. PMID- 4210489 TI - [The functional future of 61 cases of idiopathic necrosis of the femur head. Therapeutic conclusions]. PMID- 4210488 TI - Regulation of antibiotic production: catabolite inhibition and the dualistic effect of glucose on indolmycin production. PMID- 4210490 TI - Metatropic dqarfism. PMID- 4210491 TI - Primate red cell enzymes: glucose-6-phosphate dehydrogenase and 6 phosphogluconate dehydrogenase. PMID- 4210492 TI - [New profile of a resistance to aminoglycosides in Pseudomonas aeruginosa]. PMID- 4210494 TI - [Hepatitis B antigen research technics. Epidemiology at a hemodialysis and liver disease center]. PMID- 4210493 TI - [Epidemiological study of Staphylococcus aureus and Pseudomonas aeruginosa in an intensive care unit]. PMID- 4210495 TI - Observations on precipitins against a peptidase with chymotrypsin-like activity of Micropolyspora faeni, in sera of cattle exposed to mouldy hay. PMID- 4210496 TI - Eperythrozoon and Haemobartonella in monkeys. PMID- 4210497 TI - Ehnanced resistance to certain infections in vitamin A-treated mice. PMID- 4210498 TI - Augmentation of wound strength by pretreatment with epinephrine. PMID- 4210500 TI - Is chiasma determination sequential? PMID- 4210499 TI - High levels of serum complement factors in juvenille rheumatoid arthritis. PMID- 4210501 TI - Haemocyanin synthesis and the branchial gland of Octopus. PMID- 4210503 TI - Biosynthesis of biopterin by Chinese hamster ovary (CHO K1) cell culture. PMID- 4210502 TI - Ribonucleotide reductase from Euglena gracilis. A 5'-deoxyadenoslycobalamin dependent enzyme. PMID- 4210504 TI - The interaction of a cationic detergent with bovine serum albumin and other proteins. PMID- 4210505 TI - Glycosphingolipids covalently linked to agarose gel or glass beads. Use of the compounds for purification of antibodies directed against globoside and hematoside. PMID- 4210506 TI - Characterization of the functional activities of the subunits of 3-deoxy-D arabinoheptulosonate 7-phosphate synthetase-chorismate mutase from Bacillus subtilis 168. PMID- 4210508 TI - Induction of chymotrypsinogen by hydrocortisone in embryonic chick pancreas in vitro. PMID- 4210507 TI - Isolation and properties of two inhibitors of proteinase B from yeast. PMID- 4210509 TI - Diazepam inhibition of post-tetanic potentiation in bullfrog sympathetic ganglia: possible role of prostaglandins. PMID- 4210510 TI - The effects of some drugs on an evoked response sensitive to tetrahydrocannabinols. PMID- 4210511 TI - Small-intestinal bacterial flora in dermatitis herpetiformis. PMID- 4210512 TI - The role of vitreous collagen in platelet aggregation in vitro and in vivo. PMID- 4210513 TI - Multilaboratory comparison of three immunodiffusion methods used for the detection of precipitating antibodies in hypersensitivity pneumonitis. PMID- 4210514 TI - Antianginal effects of chromonar. A combined investigation. PMID- 4210515 TI - Pharmacokinetics of pivampicillin and ampicillin in man. PMID- 4210516 TI - Lidocaine disposition kinetics in monkey and man. I. Prediction by a perfusion model. PMID- 4210517 TI - Lidocaine disposition kinetics in monkey and man. II. Effects of hemorrhage and sympathomimetic drug administration. PMID- 4210518 TI - A perspective of Soviet blood banking. PMID- 4210519 TI - The relation between response to hypotonic stress and the 51Cr recovery in vivo of preserved platelets. PMID- 4210520 TI - Hepatitis B virus subtypes ad and ay among blood donors in the Greater Los Angeles area. PMID- 4210522 TI - Paraventricular "pseudotumor". A case report. PMID- 4210521 TI - Biochemical effects of denervation in subhuman primate muscles. PMID- 4210524 TI - Some applications of scintiscanning to radiation therapy. PMID- 4210523 TI - Osteoradionecrosis of the mandible resulting from external megavoltage radiation therapy. PMID- 4210525 TI - From animals to man: metabolic considerations. PMID- 4210526 TI - Pharmacodynamic and pharmacokinetic measurements of antitumor agents. PMID- 4210527 TI - Unusual extraperitoneal lesions of the pelvis. PMID- 4210528 TI - Maintenance of urinary asepsis in subhuman primates during chronic catheter drainage. PMID- 4210529 TI - Infectious process in the lungs after intranasal challenge of white mice with Rickettsia prowazekii. A histologic immunoluminescent and electron microscopic study. AB - The lungs of white mice given intranasal injections of various amounts of Rickettsia prowazekii were studied. Agent parasitism, mainly in the alveolar epithelium and nonciliated cells of bronchiolar epithelium, underlies the infectious process developing in the lungs. Rickettsiae may lodge in these cells without inducing both local and general alterations or a leukocyte response. After being released from the cells they inhabit, rickettsiae evoke acute exudative inflammation. The inflammation is accompanied by marked circulatory disorders, necrosis of exudate cells and vascular thrombosis, which are induced by toxic products of the agent. Polymorphonuclear leukocytes and macrophages represent the main defense mechanism of a host. They ingest and destroy rickettsial organisms. If infection runs a favorable course, phagocytes destroy the rickettsiae, and the organisms are entirely cleared from the lungs. PMID- 4210530 TI - [A new, safe method for diagnosing decompensated autonomous adenoma of the thyroid (author's transl)]. PMID- 4210531 TI - [Letter: Therapy of pyelonephritis in pregnancy]. PMID- 4210532 TI - [Single intravenous glibenclamide-glucose loading as a prediction test (author's transl)]. PMID- 4210533 TI - [Haemorrhagic diathesis in a newborn child of a mother on anti-epileptic medication (author's transl)]. PMID- 4210537 TI - Impact of Medicaid and an OEO health center on use of dental services in an urban area. PMID- 4210538 TI - Associations between coronary mortality and the weather, Chicago, 1967. PMID- 4210539 TI - An exploratory study of associate degree programs for mental health workers. PMID- 4210541 TI - Influence of postpartum home visits on postpartum clinic attendance. PMID- 4210542 TI - Supplying health care to nondelegates during 1972 national political conventions. PMID- 4210546 TI - Irregular reporting of tuberculosis cases by laboratories in Nassau County, N.Y. PMID- 4210544 TI - Medical costs and other aspects of dog bites in Baltimore. PMID- 4210548 TI - [Tetraplegia after nitrofurantoin treatment (author's transl)]. PMID- 4210547 TI - [The effect of mesterolone on erythropoiesis of chronically haemodialysed patients (author's transl)]. PMID- 4210549 TI - Significance of serum fungal inhibitory factor in dermatophytosis. PMID- 4210550 TI - Effects of prostaglandins on the internal and external carotid blood flow in the monkey. PMID- 4210553 TI - Letter: Central venous catheter maintenance. PMID- 4210551 TI - Proteolysis of preformed protein in wound nutrition. PMID- 4210552 TI - Effect of complete parenteral nutrition including fat emulsion on plasma lipid. PMID- 4210554 TI - Parenteral hyperalimentation. PMID- 4210555 TI - Letter: The use of nebulized Intal in asthma. PMID- 4210556 TI - [Letter: Genetic rounds in dermatology]. PMID- 4210558 TI - [Letter: Methotrexate in psoriasis]. PMID- 4210557 TI - [Diagnosis of von Willebrand's disease by means of the quantitative immunological assay of factor VIII-related antigen (author's transl)]. PMID- 4210559 TI - The day hospitals organisation: the first 4 years. PMID- 4210560 TI - The auditory system of the medulla and localization. PMID- 4210561 TI - Neurophysiological mechanisms of sound localization. PMID- 4210562 TI - Development of some mechanisms useful in sound localization. PMID- 4210563 TI - [Current possibilities in the early diagnosis of tumors of the digestive system. Introduction]. PMID- 4210564 TI - Living with long-term home dialysis. PMID- 4210565 TI - Glomerulitis in typhoid fever. PMID- 4210566 TI - Ethambutol in pregnancy: observations on embryogenesis. PMID- 4210567 TI - Pulmonary allergic granulomatosis: a possible drug reaction in a patient receiving cromolyn sodium. PMID- 4210569 TI - [Letter: Analysis of hemoglobin in Waldenstroem's disease]. PMID- 4210568 TI - The use of total-body counters for the study of iron metabolism and iron loss. PMID- 4210571 TI - Letter: Maternal blood group A and pre-eclampsia. PMID- 4210570 TI - Treatment of advanced tumours of head and neck with fast neutrons. AB - Fast neutrons interact with matter in a different way from x and gamma rays. They have been used at Hammersmith Hospital for the past four years in the treatment of advanced tumours in several sites of the body, and the results of this treatment in the first 100 cases of tumours of the head and neck are described here. Altogether 62 patients who had been referred for fast neutron therapy because it was thought that no other treatment would be effective experienced complete regression of the tumours, and only two recurred. Tumours of the buccal cavity and salivary glands responded particularly well and the relief of pain and ulceration was striking. Side effects were not serious and did not differ from those seen with supervoltage radiation, apart from the reaction of the skin. Follow-up was short, however, owing to deaths from metastases, and out of 76 patients treated more than one year previously only 30 survived. Cases which have not metastasized must therefore be treated so that the effects on tumours and adjacent normal tissues can be observed for several years after treatment. The results obtained so far indicate that it is now justifiable to use neutrons in such cases. PMID- 4210572 TI - Red cell zinc and red cell zinc metalloenzymes in hyperthyroidism. PMID- 4210573 TI - Pituitary-thyroid function after total adrenalectomy in patients with Cushing's disease. PMID- 4210574 TI - Phenolic metabolites of DL-norgestrel: a method for the removal of 1-hydroxylated metabolites, potential sources of phenolic artifacts. PMID- 4210575 TI - Electron microscopy of gonococci in the urethral secretions of patients with gonorrhoea treated with penicillin and erythromycin. PMID- 4210576 TI - Immunofluorescence staining for the detection of Neisseria gonorrhoeae in women. PMID- 4210577 TI - Modified transport and growth medium for the cultivation of Neisseria gonorrhoeae. PMID- 4210578 TI - Sensitivity to ampicillin, penicillin, and tetracyline of gonococci in Rotterdam. PMID- 4210579 TI - Growth and effect of mycoplasmas in Fallopian tube organ cultures. PMID- 4210580 TI - Sexually-transmitted diseases in women. PMID- 4210581 TI - An approach to VD control based on a study in Kingston, Jamaica. PMID- 4210583 TI - Letter: Puerperal rubella vaccination and anti-D immunoglobulin. PMID- 4210582 TI - Hepatitis B antigen in prostitutes. PMID- 4210584 TI - Phospholipids in amniotic fluid. I. Relationship of phospholipid concentrations to gestation, maternal disease and fetal outcome. PMID- 4210585 TI - The metabolism of 14C-labelled essential amino acids given by intragastric or intravenous infusion to rats on normal and protein-free diets. PMID- 4210586 TI - The metabolism of (75Se)selenite in young women. PMID- 4210587 TI - The utilization of gelled maize starch in the small intestine of sheep. PMID- 4210588 TI - Plasma fibrinogen and its fragments during streptokinase treatment. PMID- 4210589 TI - Pilus-dependence of four Pseudomonas aeruginosa bacteriophages with non contractile tails. PMID- 4210590 TI - Integrity of cell-bound poly(I).poly(C). PMID- 4210591 TI - Modifications by sodium auro-thio-malate of the expression of virulence in mice by defined strains of Semliki Forest virus. PMID- 4210592 TI - Amniotic fluid glucose concentration. PMID- 4210593 TI - Screening for gonorrhea in a low-risk population. PMID- 4210594 TI - Studies on uterine flushings in the baboon. 3. Immunochemical composition in animals with and without intrauterine contraceptive devices. PMID- 4210595 TI - Enhancement of the IgG antibody production to Escherichia coli O antigen by prior exposure to serologically different E. coli bacteria. PMID- 4210597 TI - Osteoclastic resorption of 3H-proline labelled bone, dentine and cementum in the rat. PMID- 4210596 TI - Transient antigen-specific non-reactivity of an organ induced in sensitized animals by repeated challenges. A new experimental phenomenon observed in the parotid gland of rats. PMID- 4210598 TI - Genetic control of spermiogenesis in Drosophila melanogaster: the effects of abnormal cytoplasmic microtubule populations in mutant ms(3)10R and its colcemid induced phenocopy. PMID- 4210599 TI - Dynamics of spermiogenesis in Drosophila melanogaster. IV. Nuclear transformation. PMID- 4210600 TI - Chemical modification of mushroom tyrosinase for stabilization to reaction inactivation. PMID- 4210601 TI - Seeing form. PMID- 4210602 TI - Brain damage and seeing: a new look at some old problems. PMID- 4210603 TI - The argon laser-the effect on retinal tissues and its clinical applications. PMID- 4210604 TI - Vortex patterns of the corneal epithelium. PMID- 4210605 TI - Ocular brucellosis. PMID- 4210607 TI - [Immunological diagnosis in cases of thrombosis of the central retinal vein (author's transl)]. PMID- 4210606 TI - Myocardial changes in monkeys fed mustard oil. PMID- 4210608 TI - Long-term results of carotid artery surgery for cerebrovascular insufficiency. PMID- 4210609 TI - Antibiotic susceptibility of gram-negative bacilli isolated from blood cultures. Results of tests with 35 agents and strains from 169 patients at Boston City Hospital during 1972. PMID- 4210610 TI - [Binding of ethidium bromide with nucleic acids of live microorganisms]. PMID- 4210611 TI - [Variations of evoked potentials in the optic nerve through short stimuli during dark adaptation]. PMID- 4210612 TI - [Afferent activities originating at the level of the lower beak in the domestic duck]. PMID- 4210613 TI - [Effects of broken-chain organic acids on the spontaneous and conditioned activities of the mouse]. PMID- 4210615 TI - [Studies on the determination of neural crest-cell migration]. PMID- 4210614 TI - [Preparation and properties of anti-diethyl-stilbestrol immune sera]. PMID- 4210616 TI - [Fluorescence of polyadenylic acid at ambiant temperature]. PMID- 4210617 TI - [Isolation of arabinose phosphate from the walls of Mycobacterium tuberculosis H 37 Ra]. PMID- 4210618 TI - [Electrophoretic analysis of liver mitochondrial proteins from normal and thyroidectomized rats]. PMID- 4210619 TI - Parenteral hyperalimentation. PMID- 4210620 TI - Cell fusion induced by Germiston and Wesselsbron viruses. PMID- 4210622 TI - Therapeutic intravenous alimentation for traumatic chylous ascites in a child. PMID- 4210621 TI - Jaundice, hypertrophic pyloric stenosis, and hepatic glucuronyl transferase. PMID- 4210623 TI - [Feather and bone meal as an untraditional source of nitrogenous substances in the feeding ration of ducts]. PMID- 4210624 TI - [Effect of increased temperature on the growth and serum proteins of force-fed ducklings in relation to the feed protein level]. PMID- 4210625 TI - [Strength and structure of demineralized and remineralized bones in laying-hens]. PMID- 4210626 TI - [Effect of various doses of UV radiation on leukogram values and red and white blood cell counts in the blood of broilers]. PMID- 4210627 TI - [Effect of DDT on antibody formation against the corpuscular antigen in poultry]. PMID- 4210628 TI - [Dynamics of aspartate and alanine aminotransferase activity (GOT and GPT) in the heart and skeletal muscles of starving chickens]. PMID- 4210629 TI - [Iatrogenic injuries to the great vessels and heart (author's transl)]. PMID- 4210631 TI - [Posterior superior proctotomy in villous adenoma of the rectum (author's transl)]. PMID- 4210630 TI - [Medical and social rehabilitation of pacemaker carriers (author's transl)]. PMID- 4210632 TI - [Problems involved by the insulin test as a postoperative vagotomy check (author's transl)]. PMID- 4210633 TI - [Fine structure investigations of metallosis in stainless steel allentheses (author's transl)]. PMID- 4210634 TI - [The importance of pulse cytophotometry in the early recognition of benign and malignant diseases of the gastric mucous membrane (author's transl)]. PMID- 4210635 TI - [Medical discussion with members of the family on permission to donate kidneys (author's transl)]. PMID- 4210636 TI - Human and bovine prothrombin similarities. PMID- 4210637 TI - Power spectra of pulse sequences and implications for membrane fluctuations. PMID- 4210638 TI - A stochastic model for chemical kinetics. PMID- 4210639 TI - [The systematic position of Bactritina (ammon. Cephalop.)]. PMID- 4210640 TI - [Technical advances in the surgical treatment of type I total acute aortic dissections]. PMID- 4210641 TI - [Adrenergic myocarditis, incidence in a series of 23 cases of pheochromocytomas]. PMID- 4210642 TI - [Quantitative cineangiocardiography. A statistical study of 3 simple myocardial contractility indexes. A new formulation of Starling's law]. PMID- 4210643 TI - [Coronary arteriographic data simultaneous with the initial anginal manifestations]. PMID- 4210644 TI - [Elevation of S.T. segment during isoproterenol diagnostic test]. PMID- 4210645 TI - [Statistical analysis of the amplitudes of diastolic filling waves in the left ventricular mechanical curve, in the healthy man at rest]. PMID- 4210646 TI - [Hemodynamic study of hyperthyroidism]. PMID- 4210647 TI - [Study of the dynamics of the left ventricular systole in the course of myocardial infarct]. PMID- 4210648 TI - [Late dysfunction of mitral valve prosthesis due to thrombosis. Its detection and the practical attitude required]. PMID- 4210649 TI - [A little-known postoperative complications of heart surgery: secondary tamponade. Apropos of 7 personal cases]. PMID- 4210650 TI - [Immuno-allergic pulmonary fibrosis caused by inhalation of organic dust]. PMID- 4210651 TI - [Pulmonary fibrosis in exogenous immunological lung diseases. Nosological problems]. PMID- 4210652 TI - [Aorto-pulmonary fistulas (apropos of 13 cases)]. PMID- 4210654 TI - [The lung in Fallot's tetralogy (anatomo-clinical correlations--preliminary study)]. PMID- 4210653 TI - [Aorto-pulmonary fistula. Surgical correction]. PMID- 4210655 TI - [Retrograde catheterization of the left heart chambers in children and infants using the Seldinger technic. Apropos of 283 examinations]. PMID- 4210656 TI - [Isolated pulmonary infundibular stenosis (apropos of 25 cases)]. PMID- 4210657 TI - [Hypoplasia of the tricuspid valve. Diagnosis and therapeutic results (apropos of 4 cases)]. PMID- 4210658 TI - [Anoxic pulmonary hypertension due to pharyngeal obstruction in the child (apropos of 4 cases)]. PMID- 4210659 TI - [The preoperative stage in the cardiovascular surgery in infants]. PMID- 4210660 TI - [Congenital systemic arteriovenous fistula: an unusual cause of continuous thoracic murmur]. PMID- 4210661 TI - [Left ventricular aneurysm, sequela of myocardial abscess]. PMID- 4210662 TI - [Pediatric cardiology in general practice]. PMID- 4210663 TI - [Letter: Treatment of medullary aplasia with percutaneous testosterone]. PMID- 4210665 TI - Projections from the pulvinar to the middle temporal visual area (MT) in the owl monkey, Aotus trivirgatus. PMID- 4210664 TI - Demonstration of detergent-soluble antigen specific for the synaptosomal membrane fraction isolated from the cat cerebral cortex. PMID- 4210666 TI - [Bacterial degradation of beta-muricholic acid in rats]. PMID- 4210667 TI - [Inhibitory action of alpha-1 globulins of rat serum on the in vivo multiplication of hepatic cells]. PMID- 4210668 TI - [Intra- and interstrain adoptions in the white rat. Effects on body weight and on brain weight]. PMID- 4210669 TI - [Detection of diethylstilbestrol and of progesterone in the saliva of goats and sheep subjected to implants containing these compounds]. PMID- 4210670 TI - [Analysis of inbred lineage in Drosophila melanogaster as a function of type of crossing]. PMID- 4210672 TI - [Transmission of Sarcocystis tenella, in the cat, from intramuscular parasitic cystic forms in sheep: oocysts and sporocysts in photon and electron microscopy]. PMID- 4210671 TI - [Ultrastructural study of the effects of actinomycin D on the in vitro differentiation of the uropygial vesicle rudiment]. PMID- 4210673 TI - [Phenomenon of radioprotection by previous imbibition at low temperature observed in rice seeds (Oryza sativa L.) subjected to gamma rays of Co60]. PMID- 4210674 TI - [Variation of the isotope ratio C13-C12 of CO2 emitted by the rat as a function of age]. PMID- 4210675 TI - [The 2 isoenzymes of bovine erythrocyte carbonic anhydrase are different by an Arg leads to Gln substitution in position 56]. PMID- 4210676 TI - [Isolation and characterization of N-acetyl-beta-1-4-1, 6 anhydro-N-acetylmuramic acid]. PMID- 4210677 TI - [Bacillus thuringiensis var. Berliner 1715: sporulation of a crystal--mutant; participation of mesosomes in the formation of the sporular envelopes (exosporium and tunic)]. PMID- 4210678 TI - [Induction of the synthesis of interferon in the mouse by spheroplasts and R mutants of Brucella]. PMID- 4210679 TI - Electrophysiological analysis of the effects of L-dopa on the reciprocal corticothalamic projections in the squirrel monkey. I. Iatrogenic coma and disinhibition of medial thalamic neurons. PMID- 4210680 TI - Control of stable RNA synthesis in a temperature-sensitive mutant of elongation factor G of Bacillus subtilis. PMID- 4210681 TI - Dark repair of DNA containing "spore photoproduct" in Bacillus subtilis. PMID- 4210682 TI - Inactivation of 6-phosphogluconate dehydrogenase structural gene of Drosophila melanogaster caused by translocation to heterochromatin. PMID- 4210684 TI - Tuberculous meningitis as a complication of sarcoidosis. AB - In two patients with well established sarcoidosis, the acute onset of meningitis proved to be due to tuberculosis rather than to an extension of sarcoid granulomata to the meninges. The cerebrospinal fluid changes are very similar, and the differential diagnosis rests on a search for Mycobacterium tuberculosis. PMID- 4210683 TI - Effect of supratentorial space-occupying lesions on regional intracranial pressure and local cerebral blood flow: an experimental study in baboons. AB - Cortical blood flow and epidural intracranial pressure have been measured in the two supratentorial compartments of the intracranial space in experimental baboons during the acute expansion of a parieto-occipital epidural balloon. Differential pressures between the two halves of the supratentorial space have been found, and these have been associated with evidence that flow has fallen more quickly in the hemisphere most compressed. The evidence points to a more rapid exhaustion of the autoregulatory capacity in the hemisphere subjected to greater compression, a fall in perfusion pressure to below critical autoregulatory levels occurring slightly before that in the opposite hemisphere, and the establishment of a differential flow pattern for a short time during a critical phase of compression. The displacements induced by inflation of the parieto-occipital balloon have been described. PMID- 4210685 TI - Muscle blood flow in Duchenne type muscular dystrophy, limb-girdle dystrophy, polymyositis, and in normal controls. AB - Muscle blood flow (MBF) was measured using the local (133)Xenon injection method in patients with Duchenne type muscular dystrophy (six), limb-girdle dystrophy (four), polymyositis (seven), and in normal controls (11). Measurements were made at rest and during hyperaemia induced by ischaemic exercise and by histamine injection. Capillary diffusion capacity was measured with the (51)Cr-EDTA method in three patients with Duchenne dystrophy and in six normal controls. Patients with Duchenne dystrophy had normal MBF during rest and during hyperaemia after exercise and significantly increased MBF after histamine injection. The capillary diffusion capacity was higher than normal, but not significantly. In limb-girdle dystrophy MBF was normal, while in polymyositis it was significantly decreased in all three circulatory states. The relevance of the findings to the proposed ischaemic aetiology of Duchenne dystrophy is considered. PMID- 4210687 TI - Two cases of hepatic mastocytoma in sheep. PMID- 4210688 TI - Giant cell aortitis in a South American monkey (Callimico goeldii). PMID- 4210686 TI - Use of cerebrospinal fluid drawn at pneumoencephalography in the study of monoamine metabolism in man. AB - Concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were significantly higher in CSF obtained after injection of air during pneumoencephalography (PEG) than in lumbar CSF, as drawn before the injection. There was a high correlation between levels in the 'mixed' and lumbar samples of CSF in the case of each of the two acids. The concentration of lumbar HVA, but not that of 5-HIAA, was negatively correlated with CSF pressure. 5-HIAA levels were low in both samples of CSF in a group of epileptics, by comparison with controls. In two patients with Kufs disease and in one with Niemann-Pick disease, the concentration of HVA was very low in the lumbar sample. The application of a standardized PEG technique in the study of monoamine metabolism in man is suggested. PMID- 4210689 TI - Endometriosis in four irradiated rhesus monkeys. PMID- 4210691 TI - Letter: Osteitis deformans in a macaque. PMID- 4210690 TI - Chronic eosinophilic myositis in a rhesus monkey infected with sarcosporidiosis. PMID- 4210692 TI - [Australia antigen in the West-African immigrant]. PMID- 4210694 TI - [Thyroid gland function tests with the Res-O-Mat ETR]. PMID- 4210693 TI - [Antigenic and immunogenic properties of protein sub-units obtained by the action of sodium dodecyl sulfate]. PMID- 4210695 TI - [Microbial conversion of xenobiotics in refuse composting]. PMID- 4210696 TI - [Preparation and properties of sheep haptoglobin]. PMID- 4210697 TI - A new genus of late oligocene monkey (Cebidae, Platyrrhini) with notes on postorbital closure and Platyrrhine evolution. PMID- 4210698 TI - Ecological relations and niche separation between sympatric terrestrial primates in Ethiopia. PMID- 4210699 TI - A ten-year summary of reproductive data for free-ranging Macaca mulatta. PMID- 4210700 TI - Nucleus ventroposterior inferior (VPI) as the ventibular thalamic relay in the rhesus monkey. I. Field potential investigation. PMID- 4210701 TI - Complement-induced changes in the core structure of sheep erythrocyte membranes: a study by freeze-etch electron microscopy. PMID- 4210703 TI - Purification and kinetic mechanism of rat liver glycogen synthase. PMID- 4210702 TI - Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso diaminopimelic acid interpeptide linkages in the peptidoglycan of Mycobacteria. PMID- 4210704 TI - Phasic myocardial blood content. An experimental study on effects of hypoxaemia, ischaemia and coronary drugs. PMID- 4210706 TI - Chromosome banding patterns in squirrel monkeys (Saimiri sciureus). PMID- 4210705 TI - Hematology of laboratory baboons in Kenya. PMID- 4210710 TI - [Recurrent urinary tract infections in childhood]. PMID- 4210709 TI - Relationship between plasma corticosterone and the development of ketoacidosis in the alloxan diabetic rat. PMID- 4210708 TI - Serum thyrotropin during daily life and in response to thyrotropin releasing hormone in normal subjects and juvenile diabetics. PMID- 4210711 TI - FSA-foetal sulphoglycoprotein antigen associated with gastric cancer. PMID- 4210707 TI - Comparative metabolism of drugs in man and monkeys. PMID- 4210712 TI - [Fundamentals of gout research (author's transl)]. PMID- 4210713 TI - [Incidence of primary hyperuricemia in ambulant patients (author's transl)]. PMID- 4210715 TI - [Primary amyloidosis. Case contribution]. PMID- 4210714 TI - [Primary hyperparathyroidism. I. Clinical and therapeutic aspects (author's transl)]. PMID- 4210716 TI - [Results of gastroscopy. Practical experience and evaluation (author's transl)]. PMID- 4210717 TI - [Significance of duodeno-gastric reflux]. PMID- 4210718 TI - [Radiodiagnostic problems of papillary tumor with hypotonic duodenography (author's transl)]. PMID- 4210719 TI - [Death following bee sting. Case report]. PMID- 4210720 TI - [The importance of dispensaries for medical training and the care of the sick (author's transl)]. PMID- 4210722 TI - [Proceedings: Malignant diseases of the lymph nodes]. PMID- 4210721 TI - [Lipid metabolism disorders in gout]. PMID- 4210723 TI - [Proceedings: Structural and functional aspects of pathologic pictures of the small intestine mucosa]. PMID- 4210724 TI - [Rupture and reformation of membranes during pinocytic vesiculation]. PMID- 4210725 TI - [Effect of polycarboxylate anions on hemoglobin]. PMID- 4210727 TI - Simple, inexpensive procedure for the disruption of bacteria. AB - Small volumes (1 to 2 ml) of bacterial cultures, with turbidities ranging from 3 to 10, were disrupted 50 to 90% (measured as a decrease in turbidity) within 2 min, by shaking them on a Vortex-type mixer in the presence of glass beads. This method of disrupton was effective for cells in the following genera: Streptococcus, Lactobacillus, Staphylococcus, Bacillus, and Escherichia. After low-speed centrifugation, the resulting extract can be used as potential sources for enzymes, transforming deoxyribonucleic acids, cell walls, membranes, etc. PMID- 4210726 TI - Comparative sensitivity of gel-diffusion and tube agglutination tests for the detection of Brucella canis antibodies in experimentally infected dogs. AB - The microslide gel-diffusion and macro-tube agglutination techniques to detect Brucella canis antibodies in dogs were compared. Sera from dogs experimentally infected with B. canis and a random sample of dog sera with unknown histories of exposure to this organism were examined. The results of the gel-diffusion method employing specific rough Brucella saline-extract antigens of B. canis and Brucella ovis were comparable to those obtained by the tube agglutination test. The easily prepared, stable R antigen in the freeze-dried form offers a convenient, simple, and reliable diagnostic method for the serological detection of canine brucellosis by the gel-diffusion test. PMID- 4210728 TI - Development of a defined minimal medium for the growth of Neisseria gonorrhoeae. AB - This investigation describes the development of a solid and a liquid medium (Gonococcal Genetic Medium; GGM) which support the rapid growth of 41 gonococcal clinical isolates and laboratory strains with a minimum number of nutritional components. The complete medium contains minimal salts, eight amino acids, two nitrogen bases, vitamins, coenzymes, key metabolic intermediates, and some miscellaneous components. Results indicate that GGM can be modified and simplified even further than we described. In liquid GGM, several gonococcal strains grew logarithmically after a 2- to 3-h lag period with generation times ranging from 72 to 115 min, reaching optical densities of 175 to 320 Klett units in the presence of seven amino acids and in the absence of a CO(2) atmosphere. The development of a solid and a liquid defined minimal medium such as GGM should greatly broaden the avenues of experimentation for biochemical genetic studies with N. gonorrhoeae, especially gonococcal genetic transformation. N. gonorrhoeae can be classified into eight major and minor phenotypic groups, depending on its growth responses on GGM to just five amino acids: cysteine and cystine, arginine, proline, isoleucine, and serine. Such results demonstrate the feasibility of using GGM as a simple, sensitive, rapid probe for investigating the epidemiological patterns of gonorrhea. PMID- 4210729 TI - Use of sodium polyanethol sulfonate in the preparation of 5 per cent sheep blood agar plates. AB - An alternative method to defibrinating sheep blood for use in bacteriological media is described. The new procedure incorporates sodium polyanethol sulfonate in a concentration of 0.05% (vol/vol). In testing 117 bacterial and fungal isolates, no significant differences were found with respect to adequate growth, pigment production, hemolytic reactions, and other physical attributes. Further tests demonstrate that the sodium polyanethol sulfonate in sheep blood agar plates does not cause any aberrations in zone sizes around disks used in antibiotic susceptibility tests. Consequently, the method represents a suitable alternative to the use of defibrinated sheep blood in the preparation of bacteriological media. PMID- 4210730 TI - Characterization of the precipitin bands detected in the immunodiffusion test for paracoccidioidomycosis. AB - In order to characterize the precipitin bands detected in the immunodiffusion test for paracoccidioidomycosis, a study was undertaken in 54 patients with the disease. On the basis of the pattern of known control sera, the three commonly observed lines of precipitate were designated as 1, 2, and 3 according to their location in the immunodiffusion plate. At time of diagnosis, 28 of the patients exhibited all three bands, 16 gave two bands, and 10 showed only one precipitin line. Over 50 of the sera with three bands had high complement fixation titers (above 1:512), whereas those with one band exhibited lower titers. A similar picture was obtained with the quantitative agar-gel techniques, where titers of 1:64 and above were more commonly observed in sera with three precipitin lines. Follow-up studies carried out in 18 patients revealed that band 3 disappeared first, followed by band 2, and, finally, by band 1. At the end of 2 to 3 years, 85.7% of the patients had lost band 3, 75% band 2, and only 27.7% band 1. Cross reactions with histoplasmin were found in eight patients who gave the M precipitin line with this antigen. It was found that the latter band and our paracoccidioidin band 3 fused, producing lines of identity. Bands 1 and 2 were specific. The implications of these findings are discussed. PMID- 4210731 TI - [Comparison by hemagglutination and gel diffusion of the phytohemagglutination of Pisum sativum L., Lathyrus odoratus L. and Vicia villosa Roth by means of anti Pisum immune serums]. PMID- 4210732 TI - Antibiotics excreted into the bile--action on the tone and motility of the bile duct. PMID- 4210733 TI - [Antirhoin in the treatment of gastroenteritis in newborn calves]. PMID- 4210734 TI - [Effect of chlorinated hydrocarbons on the yoghurt ripening of milk and effect of this ripening on their stability]. PMID- 4210735 TI - [Excretion of 1-naphtyl-N-methylcarbamate (Carbaryl) and 2-isopropoxyphenyl-N methylcarbamate (Aprocarb) in milk]. PMID- 4210737 TI - [Determination of serum IgG as a diagnostic test for Aleutian mink disease]. PMID- 4210736 TI - [Dehelmintization of sheep using the preparations Davainex (Spofa), Helmatac(SKF), Nilverm (ICI) and its influence on various clinical examination data]. PMID- 4210738 TI - [Effect of various surgico-orthopedic diaseases on the activity of the enzymes GOT, GPT, SODH and AP in the blood serum of horses]. PMID- 4210739 TI - [Lyophilized trivalent vaccine against canine leptospirosis]. PMID- 4210740 TI - [Use of automatic blood-cell counters in the hematological diagnosis of cattle leukoses]. PMID- 4210741 TI - [Determination of oxide concentrations in the stable air by detection tubes CO2 type 1 per cent]. PMID- 4210742 TI - [Isolation and identification of Vibrio coli and Borrelia like germs in the pig's dysentery]. PMID- 4210743 TI - [Possibilities of combined vaccination of minks against Aujeszk's disease, distemper and botulism]. PMID- 4210744 TI - [Dissociation anesthesia using ketamine in cats]. PMID- 4210745 TI - [Toxic effect of warmed-up culture of Bacillus cereus]. PMID- 4210746 TI - [Lysyl-arylamidase activity in the blood serum of domestic animals]. PMID- 4210747 TI - [Levels of oxytetracycline in the blood serum of hens, turkeys and pigeons after administration of Oxymykoin Spofa plv.solub.ad usum vet]. PMID- 4210748 TI - [Temperature and humidity regimens in halls for farrowing and suckling sows in large-capacity pig farms]. PMID- 4210749 TI - [The avian component of biocenosis in 2 poultry farms and its role in maintaining and spreading avian tuberculosis]. PMID- 4210750 TI - [Toxic activity of the disintegrated Bacillus cereus cell and endotoxin-like substances]. PMID- 4210751 TI - Purification and some properties of streptolysin O. PMID- 4210752 TI - [Cerebral acetylcholinesterase in the baboon: solubilization and electrophoretic properties]. PMID- 4210753 TI - [Interglandular relations in so-called extinctive thyroid nodules]. PMID- 4210754 TI - Intravenous hyperalimentation for the onco-surgical patient. PMID- 4210755 TI - [A fluorescence serological rapid test for the determination of spores from Bacillus anthracis using the micro culture method on nucleopore filters]. PMID- 4210756 TI - Rapid assay of proteolytic enzymes on film material. PMID- 4210757 TI - The diagnostic significance of anginal symptoms. PMID- 4210758 TI - Dilution curves studies in coumarin plasma and in artificially depleted abnormal control plasmas. PMID- 4210760 TI - Tuberculosis in mink. PMID- 4210759 TI - Some observations on the fine structure of the epidermal-dermal junction in the skin of the frog tadpole, Rana rugosa. PMID- 4210762 TI - The organization of the second visual area (V II) in the owl monkey: a second order transformation of the visual hemifield. PMID- 4210761 TI - Iron absorption after splenectomy in hereditary spherocytosis. PMID- 4210763 TI - Dynamic patterns of brain cell assemblies. IV. Mixed systems. Influence of exogenous low-level currents. Are weak oscillating fields detected by the brain? PMID- 4210765 TI - A survey for sarcosporidial cysts in east African game animals. PMID- 4210764 TI - Survival of Listeria monocytogenes in soil and water. PMID- 4210766 TI - A note on the blood parasites of some birds from the Republic of Madagascar. PMID- 4210767 TI - Parasites of the tide pool fish Liparis atlanticus (Osteichthyes:Liparidae). PMID- 4210768 TI - Indications of a viral etiology for marble spleen disease in pheasants. PMID- 4210769 TI - Isolation of viruses from wild mammals in West Africa, 1966-1970. PMID- 4210770 TI - [The Herskovits implant. Preliminary report on a new implantation method]. PMID- 4210771 TI - The distribution and character of glomerular deposits in systemic lupus erythematosus. PMID- 4210772 TI - Acidic fraction of ribosomal proteins from Lactobacillus acidophilus. PMID- 4210773 TI - Localization of intracellular antigens by immunoelectron microscopy. PMID- 4210774 TI - The negatively charged protein extracted from Tetrahymena pyriformis as an attractant in Amoeba proteus chemotaxis. PMID- 4210775 TI - Further studies on the factor in lung-conditioned medium stimulating granulocyte and monocyte colony formation in vitro. PMID- 4210776 TI - Method for the analysis of tRNA patterns in Drosophila melanogaster using an amino acid analyser. PMID- 4210778 TI - Somple flow-cell for the fluorimetric study of conformational changes of proteins on agarose matrix. PMID- 4210777 TI - A scanning dual wavelength spectrophotometer: application to the study of photosynthetic electron transport. PMID- 4210779 TI - Radioimmunoassays of 3,4,5-trimethoxyphenethylamine (mescaline) and 2,5-dimethoxy 4-methylphenyl-isopropylamine(DOM). PMID- 4210780 TI - Analysis of polypeptide molecular weights by electrophoresis in urea. PMID- 4210782 TI - Brinolase for lens extractopm in cynomolgus monkey (Macaca fascicularis). A toxicity study. PMID- 4210781 TI - Effect of brinolase on lens extraction in cynomolgus monkeys (Macaca fascicularis). A double blind study. PMID- 4210783 TI - [Specialized areas of presynaptic membranes]. PMID- 4210784 TI - [Effect of chromomycin A3 on the chromosomes of Pleurodele egg blastomeres in segmentation. Comparison with other chromatoclastic substances]. PMID- 4210785 TI - [Radioimmunoassay of 5-alpha-androst-16-en-3-one, steroid responsible for boar odor, in the adipose tissue of swine]. PMID- 4210787 TI - [Increase in milk production by exogenous intake of 17-beta-estradiol at the end of gestation in the ewe]. PMID- 4210786 TI - [Effect of hydrogen ions and tetraethylammonium ions on the depolarizing response of the phasic striated muscle fiber of crab (Carcinus maenas)]. PMID- 4210788 TI - [In vivo and in vitro lipolytic effect of swine somatotropin on the adipose tissue of normal and hypophysectomized rabbits]. PMID- 4210789 TI - [Electron microscopic demonstration of nerve endings of retinal origin in the anterior hypothalamus of ducks]. PMID- 4210790 TI - [The nucleic acid of the virus of the coleopteron Oryctes rhinoceros L: a superhelicoidal DNA of high molecular weight]. PMID- 4210791 TI - [Arthrogenic activity of D waxes from Calmette-Guerin bacillus]. PMID- 4210792 TI - [Ultrastructure of thymus type and bone marrow type lymphocytes. Morphological and morphometric criteria]. PMID- 4210793 TI - [Does a specific urinary protein in the cancer patient exist? New studies by 2 methods of separation of urinary proteins]. PMID- 4210794 TI - [Production of tumors in the hanster by transplantation of cells transformed in vitro by dimethyl-7,10 benzo(c)acridine]. PMID- 4210795 TI - Reversed-phase liquid chromatography of some pesticides and related compounds. Solubility-retention relationships. PMID- 4210796 TI - Schwann cells and perineurium in neuroma. Some morphological aspects. PMID- 4210797 TI - Distribution of goldthioglucose in mice with and without experimental allergic encephalomyelitis. PMID- 4210799 TI - Trisomy for short arm of chromosome 20. PMID- 4210798 TI - Ultrastructural reorganization, DNA synthesis and mitotic division of myocytes in atria of rats with left ventricle infarction. An electron microscopic and autoradiographic study. PMID- 4210801 TI - [Editorial: Juxta-ampullar duodenal diverticulum and biliopancreatic disease]. PMID- 4210800 TI - The pharyngeal hypophysis in some laboratory animals. PMID- 4210802 TI - [Disodium cromoglycate, a new drug in the prevention of bronchial asthma]. PMID- 4210803 TI - The natural history of endogenous skin malignancy as a basis for experimental research. PMID- 4210805 TI - [New knowledge on the pathogenesis, physiopathology and economic treatment of obesity]. PMID- 4210804 TI - [Cases of sudden death as a consequence of long-term work with nitric esters of glycerine]. PMID- 4210807 TI - [Zenker's diverticulum: treatment by cervicotomy or endoscopic surgery]. PMID- 4210806 TI - [Lysosomal enzymes of lymphocytes in normal and pathologic conditions]. PMID- 4210808 TI - [Ureteral diverticulum: considerations on 7 cases]. PMID- 4210809 TI - [Chagas' disease and blood transfusion]. PMID- 4210810 TI - WHO Expert Committee on Malaria: sixteenth report. PMID- 4210811 TI - [Dysgammaglobulinemia in patients with respiratory tract allergies]. PMID- 4210812 TI - Polyribosomes associated with the Golgi apparatus. PMID- 4210813 TI - The influence of juvenile hormone on the plasma membrane of symbiotic bacteria. PMID- 4210814 TI - Typing of Pseudomonas aeruginosa. PMID- 4210815 TI - [Duodenal diverticula. Comments on 60 cases]. PMID- 4210816 TI - [Immunoglobulins deficiency as a fatal prognostic sign in leukemia and lymphoreticular diseases]. PMID- 4210818 TI - [RHnull disease]. PMID- 4210817 TI - [Prenatal diagnosis of enzyme defects illustrated by a case of angiokeratoma corporis diffusum (Fabry's disease)]. PMID- 4210819 TI - Wernicke's encephalopathy in a child with congenital cardiomegaly. 2. Morphological aspects and pathogenetic considerations. PMID- 4210820 TI - [A case of Recklinghausen's neurofibromatosis]. PMID- 4210822 TI - [Interest of pyruvate medium for the culture of tuberculosis bacillus in Africa]. PMID- 4210821 TI - Frustration and self-aggression in social isolate rhesus monkeys. PMID- 4210823 TI - [Phenytoine poisoning during therapeutic association with disulfiram]. PMID- 4210824 TI - Studies in partially-treated and chronic gonococcal urethritis. PMID- 4210825 TI - Protein-calorie malnutrition in West African children. PMID- 4210826 TI - Magnesium deficiency. PMID- 4210827 TI - Clinico-electroencephalographic study of epilepsy after head injury. PMID- 4210828 TI - Latex agglutination test for invasive amoebiasis. PMID- 4210829 TI - [Embryonal osteochondropathies. Recent progress]. PMID- 4210831 TI - The nutrition problem in India. PMID- 4210832 TI - [Surgery and nutrition]. PMID- 4210830 TI - [Antibodies against non-hemoglobin proteins of hemolysates in polytransfused children]. PMID- 4210833 TI - Asthma preventive developed. PMID- 4210835 TI - [Parenteral feeding using amino acid solutions]. PMID- 4210834 TI - [Problems of parenteral feeding]. PMID- 4210837 TI - [Long-term treatment of bronchial asthma (author's transl)]. PMID- 4210836 TI - [Successful inhibition of D-sensitization following the administration of Rh positive blood to Rh-negative recipients through high doses of IgG-anti-D]. PMID- 4210838 TI - [Epilepsy in children]. PMID- 4210839 TI - Population genetic studies in Nigeria. PMID- 4210840 TI - [Effect of sympatholytics on the retinal vascular system]. PMID- 4210841 TI - Nycthemeral variation in the parasitaemia of Trypanosoma minasense in naturally infected marmosets of the genus Callithrix (primates, Callithricidae). PMID- 4210843 TI - [Reaction of plasma TSH and T3 to TRH, with special reference to 3 consecutive loading]. PMID- 4210842 TI - [Study of the pathogenicity of Leptomonas pessoai in mice, after administration of high doses of corticosteroid]. PMID- 4210844 TI - Rhesus non-isoimmunization. A review and case report. PMID- 4210845 TI - Juvenile hormone and the adult development of Drosophila. PMID- 4210846 TI - The effects of heavy metal ions on the motility of sea urchin spermatozoa. PMID- 4210848 TI - A comparison of the absorption of effervescent preparations of paracetamol and penicillin V (phenoxymethylpenicillin) with solid dose forms of these drugs. PMID- 4210847 TI - DMSO: a new respiratory stimulant? PMID- 4210849 TI - [Incidents and accidents during therapy with long-acting neuroleptics]. PMID- 4210850 TI - [A 2d antigen-antibody system in viral hepatitis]. PMID- 4210851 TI - [Amino sugar polymers with free amino groups (author's transl)]. PMID- 4210853 TI - [Eye damage caused by drugs]. PMID- 4210852 TI - [Experiences with the preparation and purification of endothelial specimens]. PMID- 4210854 TI - [Oral heart therapy using convallaria glycosides in ambulatory practice]. PMID- 4210855 TI - The role of genetics in human cancer. PMID- 4210856 TI - Lymphomas--troublesome problems in management. PMID- 4210857 TI - Precancerous lesions of the uterine cervix in pregnancy. PMID- 4210858 TI - Unproven methods of cancer management. Grape diet. PMID- 4210859 TI - Early diagnosis of colorectal cancer. PMID- 4210860 TI - Endoscopic examination of the colon and rectum. PMID- 4210861 TI - Malignant scrotal masses in children. PMID- 4210862 TI - Alexander Hughes Bennett (1848-1901) and Rickman John Godlee (1849-1925). PMID- 4210863 TI - A case of cerebral tumor--the surgical treatment. PMID- 4210864 TI - Editorial: Cancer nursing--something old, something new. PMID- 4210865 TI - Radiation enteritis. PMID- 4210866 TI - Intravenous hyperalimentation protocol. PMID- 4210867 TI - [Idiopathic disseminated racemose pulmonary ossification. (Case report and differential diagnosis) (author's transl)]. PMID- 4210868 TI - Use of cromolyn sodium in childhood asthma. PMID- 4210869 TI - Human cancer virus vaccines. PMID- 4210870 TI - Diagnosis and management of common skin cancers. PMID- 4210871 TI - Metastatic cervical nodes of unknown primary origin. PMID- 4210872 TI - Evarts A. Graham (1883-1957). PMID- 4210873 TI - Successful removal of an entire lung for carcinoma of the bronchus. PMID- 4210874 TI - Editorial: A patient's right to die--the easy way out? PMID- 4210875 TI - [Drug resistance system of Mycobacterium tuberculosis to RFP]. PMID- 4210876 TI - [Clinico-therapeutic observations on the use of a new oral hypoglycemic drug (HB 419-297 R)]. PMID- 4210877 TI - Cell interaction in conjugation of ciliates. PMID- 4210878 TI - Beta, gamma unsaturated amino acids as irreversible enzyme inhibitors. PMID- 4210879 TI - Chelating agents for the binding of metal ions to macromolecules. PMID- 4210880 TI - Lymphocyte transformation in human Plasmodium falciparum malaria. PMID- 4210881 TI - Recovery from anti-IG induced immunosuppression: implications for a model of Ig secreting cell development. PMID- 4210882 TI - The role of activated macrophages in specific and nonspecific cytostasis of tumor cells. PMID- 4210883 TI - A new one-step method for the functional assay of the fourth component (C4) of human and guinea pig complement. PMID- 4210884 TI - TRIC type K, a new immunologic type of Chlamydia trachomatis. PMID- 4210885 TI - Distribution of isotypic and allotypic human IgG antigens in non-human primates. PMID- 4210886 TI - Immunoglobulin expression of cells from human lymphoblastoid lines. I. Heavy and light chain antigens of the cell surface. PMID- 4210887 TI - Immunoglobulin expression of cells from human lymphoblastoid lines. II. Interrelationship among surface, cellular, and secreted immunoglobulins. PMID- 4210888 TI - Human lymphocyte membrane immunoglobulin as a reflection of maturation. PMID- 4210889 TI - The capping of surface immunoglobulin on mouse myeloma cells. PMID- 4210890 TI - Specific assay of gentamicin in the presence of penicillins and cephalosporins. Use of commercially manufactured beta-lactamases. PMID- 4210891 TI - Studies of the formation of a violet-reddish pigment from the cephalosporin derivative celospor (C 36,278-Ba). PMID- 4210892 TI - Preliminary clinical experience with ticarcillin (BRL 2288) in 101 patients treated for severe respiratory infections. PMID- 4210893 TI - Clinical and laboratory investigations on ticarcillin, an anti-pseudomonal antibiotic. PMID- 4210894 TI - Interaction aspects of antimycobacterial drugs in the chemotherapy of tuberculosis. II. The role of rifampicin and other drugs in the dependent or independent action of drug associations in vitro. PMID- 4210895 TI - Alterations in the sensitivity pattern after use of trimethoprim-sulfamethoxazole for two years in the treatment of urinary tract infections. PMID- 4210896 TI - [Can the difference in resistance to acute hypoxia between male and female mice be modified by injections of sex hormones to newborn animals?]. PMID- 4210897 TI - [Circadian rhythms of induced ethanolemia parameters in six healthy young adult males]. PMID- 4210898 TI - [Fetal control of parturition in the sow. Interactions with luteal function]. PMID- 4210899 TI - [The morphological stability of the ripe oocyte in Bombyx mori L]. PMID- 4210900 TI - [Evolution of the germinal line in the testis of Piophila casei (Diptera)]. PMID- 4210901 TI - [Differentiation of the endoderm in digestive tract of the chick embryo cultured in vitelline membrane, in absence of mesenchyma]. PMID- 4210902 TI - [Detection of the host vector of Nephrotrema truncatum (Leuckart 1842) (Trematoda) and demonstration of a hepatic phase during migration of the parasite in the final host]. PMID- 4210903 TI - [Cytologic study of neurosecretory cells in Lineus ruber and Lineus lacteus (Heteronemertes)]. PMID- 4210904 TI - [Ultrastructural localization of ribonucleoproteins at the level of mitotic chromosomes]. PMID- 4210905 TI - [Study of the relation between body adipose mass regulation and the lipid composition of its regulating centers]. PMID- 4210906 TI - [Use of electrophoresis for the detection of metachromatic leukodystrophy from human leukocytes]. PMID- 4210907 TI - [Demonstration of a post-synaptic permeability to calcium in Aplysia]. PMID- 4210908 TI - [In vitro synthesis of an RNA used as a primer for DNA replication]. PMID- 4210909 TI - [Relation between optic absorption spectrum and structure of nitrosyl hemoglobin]. PMID- 4210910 TI - [Characterization of the lipoprotein lipase of rat adipose tissue]. PMID- 4210911 TI - [Role of sialic acid on the survival of rabbit erythrocytes in the blood circulation]. PMID- 4210912 TI - [Research on the conformation of gamma-aminobutyric acid]. PMID- 4210913 TI - [Studies on the toxicity of 9-hydroxyellipticine]. PMID- 4210914 TI - [Role of spherocrystals of intestinal epithelium in the resistance of an insect to mineral pollutions: experimental data obtained by use of the electron microprobe and micro-analyser by secondary ionic emission]. PMID- 4210915 TI - [Studies on graft immunity in nemerteans of the genus Lineus. Study of the primary reaction to heterospecies transplantation]. PMID- 4210916 TI - Serologic group relationship of P and U streptococci. PMID- 4210917 TI - The distribution of blood group frequencies in mainland Tanzania Africans. PMID- 4210918 TI - Amniotic fluid bilirubin quantitation in the management of the Rh sensitized female. PMID- 4210919 TI - Microdetermination of alpha-amino-acids through chelation with copper and titration with EDTA. PMID- 4210920 TI - [Methodological aspects of the prognathism problem in the morphological comparison of primate skulls]. PMID- 4210922 TI - [Role of limited lesions in partial memory deficits]. PMID- 4210921 TI - [Demonstration of tubercle bacilli by culture and animal experiment (author's transl)]. PMID- 4210923 TI - Gonococcal infections. Laboratory, clinical and epidemiological aspects. PMID- 4210925 TI - [Ugh--again a long term care patient]. PMID- 4210924 TI - Serologic detection of breast cancer. PMID- 4210926 TI - [Just to be sure analyze health and illness care]. PMID- 4210927 TI - [Health hazards by high energy rays]. PMID- 4210928 TI - Studies on the live attenuated rubella virus vaccine. PMID- 4210929 TI - [Detection of glomerular basement membrane components in the urine by immunochemical analysis and the clinical significance of its results]. PMID- 4210930 TI - [Bone marrow hematopoiesis in Macaca rhesus monkeys in chronic irradiation]. PMID- 4210931 TI - [Certain new principles characterizing species-specific radiosensitivity of mammals]. PMID- 4210932 TI - [Reproductive function of monkeys, having survived acute radiation sickness]. PMID- 4210933 TI - The Mm. subcostales in man and monkeys. PMID- 4210934 TI - [A need for increase in compensation for night duties]. PMID- 4210935 TI - [Discussion: nursing in the age of highly advanced medicine]. PMID- 4210936 TI - [Humane nursing at the ICU]. PMID- 4210937 TI - [Sensitivity of the nurse in nurse-patient interaction]. PMID- 4210938 TI - [Bedside nursing. Assistance in rehabilitation of a patient with chronic tuberculosis]. PMID- 4210940 TI - [Conference. Assistance in activities of daily living of patients with decreased pulmonary function]. PMID- 4210939 TI - [Bedside nursing. Psychological approach to the problem of aprenhension of patients in the ICU]. PMID- 4210941 TI - [Introduction of foreign literature and discussion: "Mouth care"]. PMID- 4210943 TI - [Average length of hospitalization in various disease categories]. PMID- 4210942 TI - [Theory of assistance in modern counseling. 6. The authentic relationship in patient-therapist relationship]. PMID- 4210945 TI - [The temperature and the human body]. PMID- 4210944 TI - [Mental retardation and genetics]. PMID- 4210946 TI - [Multiple loop structure and homeostasis. Simple parallel connections]. PMID- 4210947 TI - [Abnormal personality. 3. Etiology of abnormality]. PMID- 4210948 TI - [Rare occulo-oto-nasal anomaly with cleft lip and palate]. PMID- 4210949 TI - Pseudomonas resistance due to inactivated susceptibility disks. AB - The deterioration of carbenicillin is similar to that of other penicillins. Susceptibility test results, by using disks which have been exposed to humidity, may indicate false resistance. Proper storage and handling methods are suggested. PMID- 4210950 TI - Haematological and plasma biochemical parameters in adult male sheep. PMID- 4210951 TI - [Effect of the technic of blood specimen collection on various patterns in bovine blood]. PMID- 4210953 TI - On the morphology of testicular and ampullar spermatozoa in Egyptian buffalo bulls. PMID- 4210952 TI - [Hypnodil for general anesthesia in porcine abdominal surgery]. PMID- 4210954 TI - Investigations on urinary oestrogen excretion from ewes with special reference to the clinical condition of the genital tract. 3. Non-breeding season. PMID- 4210955 TI - Effect of gestyl on the urinary excretion of oestrogen in ewes during the non breeding season. PMID- 4210956 TI - [Ectopic canine ureteral openings into urinary tract and renal malposition. Two case reports]. PMID- 4210958 TI - Effect of isonicotinic acid hydrazide and polyvinylpyrrolidone on experimental peritoneal adhesions in the rabbit. PMID- 4210957 TI - Myopathy in an irish terrier with a metabolic defect of the isolated mitochondria. PMID- 4210959 TI - [Intubation spatula for miniature pigs. Experiences on intubation mortality]. PMID- 4210960 TI - [The effect of detergents containing biologically active proteolytic enzymes on the skin]. PMID- 4210961 TI - [Simultaneous occurrence of Osler-Weber disease and IgA myeloma with severe antibody deficiency syndrome]. PMID- 4210962 TI - [Clinico-radiological considerations on duodenal diverticula]. PMID- 4210963 TI - [Indications and effectiveness of orally administered adrenergic sympathomimetics in the prolonged treatment and in prevention of attacks of bronchial asthma]. PMID- 4210964 TI - [Battered children hospitalized in neuro-surgery. (Clinical and medico-legal problems]. PMID- 4210965 TI - [Modifications induced in post-prandial glycemia and insulinemia by treatment with glibenclamide and with a combination of glibenclamide and phenformin]. PMID- 4210966 TI - [Results with a high-dose propicillin (Bayercillin Mega) as antibiotic of choice in 100 cases of odontogenic suppuration]. PMID- 4210967 TI - [Triatoma williami Galvao, Souza e Lima, 1965, captured in Mato Grosso. Brazil, new vector of Chagas disease]. PMID- 4210968 TI - Critical issues in infancy and early child development. PMID- 4210969 TI - Distribution and life cycle stages of lung mites (Pneumonyssus spp.). PMID- 4210970 TI - [The problem of hospitalism (author's transl)]. PMID- 4210971 TI - [Possibilities and limitations of local skin disinfection (author's transl)]. PMID- 4210972 TI - [Demonstration of 2 low molecular weight factors, 1 secreted by the thymus gland, the other by activated T cells, conferring theta antigen to theta negative lymphocytes]. PMID- 4210973 TI - [Effect of nickel sulfate on the growth of 2 human lymphoblastoid cell lines of normal and leukemic origin]. PMID- 4210974 TI - Solid tissue masses formed in vitro from cells cultured on artificial capillaries. PMID- 4210975 TI - [Current status of pathological anatomy in precancerous conditions of the digestive system (esophagus and stomach)]. PMID- 4210976 TI - [Nocturnal changes in thyroxine and in the index of triiodothyronine saturation in normal subjects]. PMID- 4210977 TI - Letter: Gonorrhea in obstetrics and gynaecology. PMID- 4210978 TI - Transabdominal isthmic amniocentesis in RH-immunization with particular reference to complications. PMID- 4210979 TI - Plasma levels of nonconjugated oestradiol-17beta and oestriol in high risk pregnancies. PMID- 4210980 TI - Dependence of radiation induced aneuploidy from chromosomal length in Drosophila melanogaster. II. X chromosomes and X-4 duplication chromosomes. PMID- 4210981 TI - Irradiation-induced crossing-over in Drosophila males. Cytological investigation of crossovers. PMID- 4210982 TI - Study of the operon of riboflavin biosynthesis in Bacillus subtilis. IV. Regulation of the synthesis of riboflavin synthetase. Investigation of riboflavin transport through the cell membrane. PMID- 4210983 TI - [The TRH test in normal subjects and in thyroid pathology: behavior of plasma TSH after stimulation with hypothalamic TRH (thyrotropin releasing hormone)]. PMID- 4210984 TI - Functional recovery after lesions of the nervous system. II. Recovery of function after lesions of the central nervous system: history and prospects. PMID- 4210985 TI - Functional recovery after lesions of the nervous system. 3. Developmental processes in neural plasticity. Sparing of language functions after early unilateral brain damage. PMID- 4210986 TI - Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Equipotentiality and sensorimotor function. PMID- 4210987 TI - Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Redundancy as a possible mechanism for escape or recovery from somatic sensory deficits. PMID- 4210989 TI - Mutants of Bacillus subtilis with altered capacity to be donors of DNA in spontaneous transformation. I. Method of isolating mutants. PMID- 4210988 TI - Functional recovery after lesions of the nervous system. V. Neural plasticity and behavioral recovery in the central nervous system. Recovery of function after sequential ablation of the frontal lobes of monkeys. PMID- 4210990 TI - Remote cytogenetic effect of acute irradiation in monkeys. I. Prolonged persistence of chromosome damage in marrow cells. PMID- 4210991 TI - Experimental digital replantation after prolonged cooling. PMID- 4210992 TI - [Question of bactericidal effect of a combination of maximally tolerable doses of INH, Myambutol and Rifadin on experimental tuberculosis]. PMID- 4210993 TI - The differential radiologic diagnosis of bone tumors. PMID- 4210994 TI - Anaemia in early infancy. PMID- 4210995 TI - [Phlorhizin inhibition of the activity of various carbohydrates on the calcium absorption]. PMID- 4210996 TI - Immunological properties of membrane fractions from wild type and dnaA mutants of Escherichia coli. PMID- 4210997 TI - DNA polymerase activities in Vero cells infected with herpesvirus Saimiri. PMID- 4210998 TI - [Isolation and study of anti-fragment lambda light chain fragment antibodies with immunoadsorbants]. PMID- 4211000 TI - Excessive hospitalization can be cut back. PMID- 4210999 TI - Properties of 5'-nucleotidase from Bacillus cereus obtained by washing intact cells with water. PMID- 4211001 TI - Studies on liver mitochondrial 5'-endonuclease activity in rats fed carcinogenic amines and on their binding to mitochondrial proteins. PMID- 4211003 TI - [Operative conditioning of the white rat: improvement of performance by the transitory lengthening of the reinforcement period]. PMID- 4211002 TI - [Histopathological study of the heart-damaging effects of thio-tepa in the chick embryo "in situ". 3]. PMID- 4211004 TI - [Data on the organogenesis of the female genital tract of the pyralid Lepidoptera Galleria mellonella L. obtained after implantation of the ovaries in castrated and non-castrated larvae]. PMID- 4211005 TI - [A case of heterosis in Drosophila melanogaster]. PMID- 4211006 TI - [Application of attenuated total reflection infrared spectrometry to the study of residues of several phytopharmaceutical products]. PMID- 4211007 TI - [Secretion of the androgenic gland of malacostracan Crustacea: purification of substance with androgenic activity]. PMID- 4211009 TI - Fate of auricular transplants and repair of auricular gaps in the grivet monkey (Cercopithecus aethiops aethiops). PMID- 4211008 TI - Histochemical observations on the development of interstitial gland tissue during the maturation of marmoset ovary. PMID- 4211010 TI - [Guanidine derivatives in the treatment of patients with diabetes mellitus]. PMID- 4211011 TI - Activity programs for long term care institutions. PMID- 4211012 TI - Evaluation of amino acid mixtures for total parenteral nutrition. PMID- 4211013 TI - Proceedings: Inhibitory effect of beta-aminopropionitrile on several amine oxidases. PMID- 4211014 TI - [2 cases of sepsis due to Pseudomonas aeruginosa]. PMID- 4211015 TI - [Meningococcal infections]. PMID- 4211016 TI - Luminal events of lipid absorption in protein-calorie malnourished children; relationship with nutritional recovery and diarrhea. I. Capacity of the duodenal content to achieve micellar solubilization of lipids. PMID- 4211017 TI - Luminal events of lipid absorption in protein-calorie malnourished children; relationship with nutritional recovery and diarrhea. II. Alterations in bile acid content of duodenal aspirates. PMID- 4211018 TI - Vitamin B6 metabolism in women using oral contraceptives. PMID- 4211019 TI - Basal energy metabolism in protein-calorie malnutrition and vitamin A deficiency. PMID- 4211020 TI - Properdin factor D. II. Activation to D by properdin. AB - The protein in the properdin pathway responsible for conversion of precursor factor D to D has been isolated and found to be identical with properdin. Sequential ion exchange and gel filtration chromatography demonstrated identity between properdin protein, measured by radial immunodiffusion, and the capacity to activate D to D, assessed by formation of the intermediate, EAC43B(D). Properdin, purified in this manner, was homogeneous on acid polyacrylamide disc gel electrophoretic analysis, with the band of protein corresponding to the position of eluates in the replicate gel capable of activating highly purified D. Demonstration of the homogeneity of purified D by alkaline disc gel electrophoresis, coupled with the linear stoichiometric hemolytic titrations of each factor, indicates that direct interaction between properdin and D generates D. Thus, activation of D by properdin represents a mechanism in the properdin pathway by which D becomes available for formation of the C3b-dependent C3 convertase. PMID- 4211022 TI - Schistosoma mansoni: immediate hypersensitivity to adult antigens in the rat. PMID- 4211021 TI - Specific binding of nerve growth factor (NGF) by murine C 1300 neuroblastoma cells. AB - Murine C 1300 neuroblastoma cells bind with high avidity on their membrane surface the nerve growth factor (NGF), a protein capable of inducing differentiation of sympathetic nerve cells. The total binding capacity of NGF by the cells was quantitatively measured by a radioimmunoassay technique, using (125)I-labeled NGF. An average number of about 10(6) molecules of NGF could be bound, at saturation, by each cell with an average relative association constant of about 10(7) liters/mol. Using synchronized cells, it was found, however, that either the number of molecules of ligand bound or the avidity of the binding interaction between NGF and cells varied depending upon their growth cycle, the maximal-binding occurring during the G(1) and early S phase. Binding of [(125)I]NGF was suppressed by trypsin treatment of the cells, however new receptor sites were rapidly replaced onto the membrane surface within 1-2 h. Cells exposed to 3 M KCl released into the supernate a protein product exhibiting similar high avidity for NGF. Acrylamide gel electrophoresis suggested a restricted molecular heterogeneity of this product, with a major component in the 52,000 mol wt region. Antibodies made specific to this protein were capable, in the absence of the complement, of inhibiting the binding of [(125)I]NGF by the cells and in the presence of the complement they killed them. PMID- 4211023 TI - Aspects of experimental hepatocarcinogenesis. IV. Changes in the liver following cessation of carcinogen administration. PMID- 4211024 TI - Extended surgical adjuvant thiotepa for mammary carcinoma. PMID- 4211025 TI - Are elemental diets useful in bowel preparation? PMID- 4211027 TI - [Rehabilitation nursing of a retarded patient with cerebral apoplexy]. PMID- 4211026 TI - [Effect of radiosensitizer (monoiodoacetate) on the recovery of sublethally damaged cells of blue-green alga, Anacystis nidulans]. PMID- 4211028 TI - Nephritogenic glycoprotein. 3. Immunochemical studies on nephritogenic activity of homologous water-soluble glycoproteins extracted from various rat organs. PMID- 4211029 TI - Identification of lymphocyte-dependent antibody in sera from multiply transfused patients. PMID- 4211030 TI - [Evolution of plasma testosterone and androstenedione levels in the male guinea pig during the 1st 3 weeks of life]. PMID- 4211031 TI - [Problem of prevention of hemolytic disease of newborn]. PMID- 4211032 TI - Carbon-13 nuclear magnetic resonance studies of structure and function in thyrotropin-releasing factor. Determination of the tautomeric form of histidine and relationship to biology activity. PMID- 4211033 TI - Functional recovery after lesions of the nervous systems. 3. Developmental processes in neural plasticity. Recovery of function after CNS lesions in infant monkeys. PMID- 4211034 TI - Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Recovery of motor function in rhesus monkeys. PMID- 4211035 TI - [Pathomorphology of primary aspergilloma of the paranasal sinuses]. PMID- 4211036 TI - [Radiographic image of the congenital diverticulum and aneurysm of the left chamber]. PMID- 4211037 TI - [Hepatolenticular degeneration]. PMID- 4211038 TI - Iron absorption from Southeast Asian diets. PMID- 4211039 TI - [Tolerance of a corticoid long-term therapy using triamcinolone acetonide in patients with recurring pulmonary sarcoidosis]. PMID- 4211040 TI - Macroglobulinemia-myeloma double gammopathy. A study of four cases and a review of the literature. PMID- 4211041 TI - [Pathogenesis of experimental invasions of Haemonchus contortus and Trichostrongylus colubriformis in lambs and its changes after treatment with Nilverm (ICI)]. PMID- 4211042 TI - [DNA synthesis during early phasis of regeneration of hind limbs in Desmognathus fuscus]. PMID- 4211043 TI - The receptor proteins for concanavalin A and Lens culinaris phytohemagglutinin in the membrane of the human erythrocyte. PMID- 4211044 TI - Regulation of aromatic amino acid biosynthesis in Bacillus subtilis 168. Purification, characterization, and subunit structure of the bifunctional enzyme 3-deoxy-D-arabinoheptulosonate 7-phosphate synthetase-chorismate mutase. PMID- 4211045 TI - [Differentiation of explanted blastular areas of Bufo arenarum]. PMID- 4211046 TI - [Explants of the 1st 4 macromeres of Bufo arenarum eggs]. PMID- 4211047 TI - [Duodenoscopy (author's transl)]. PMID- 4211048 TI - Formation and release of 3H-tryptamine from 3H-tryptophan in rat spinal cord slices. PMID- 4211050 TI - Giant duodenal diverticula. PMID- 4211049 TI - The effect of ventromedial tegmental lesions on the disposition and biosynthesis of dopamine and serotonin. PMID- 4211051 TI - Giant sigmoid diverticulum. PMID- 4211052 TI - Large diverticulum of the anal canal. Case report and review of the literature on anal canal and rectal diverticula. PMID- 4211053 TI - Radiotherapy of tumors of the urinary tract. Hickey lecture, 1974. PMID- 4211054 TI - Studies on the E strain of Rickettsia prowazeki. AB - Cultivation of E strain of Rickettsia prowazeki in mouse lung resulted in a marked increase in virulence for guinea pigs following 12 passages (but not 6 passages) in both immunosuppressed and normal mice. Attempts at passaging E strain in normal guinea pigs were unsuccessful. Isolates of E strain in the chicken embryo yolk sac either from testes and peritoneal washings or from the brain of immunosuppressed guinea pigs did not show enhanced virulence for guinea pigs. PMID- 4211055 TI - Immuno-epidemiology of malaria: a study in a tribal area of West Irian. AB - An investigation of malariometric indices in relation to immunoglobulin levels, rheumatoid factors, and antithyroglobulins was carried out on 78 members of the Arfak tribe near Manokwari in Western New Guinea, in the course of a WHO assessment of malaria control activities in that region. The population investigated had been exposed to a period of epidemic malaria, as indicated by the small differences in malariometric indices between consecutive age groups. Typically high spleen sizes were recorded, as found generally among Papuans in similar situations. Falciparum malaria was most prevalent, almost equal to cases of vivax and malariae malaria together. IgM levels were very high, while those of IgG, IgA and IgD were not elevated. Total serum protein was rather low. No correlation between malariometric indices, autoantibodies, and immunoglobulin levels could be found. In particular there was no correlation between IgM levels and spleen indices, such as has been found in many other surveys. It is suggested that splenomegaly may show no correlation with the IgM level in Papuan populations without previous selection. PMID- 4211056 TI - A serogroup A meningococcal polysaccharide vaccine: studies in the Sudan to combat cerebrospinal meningitis caused by Neisseria meningitidis group A. AB - Vaccination against cerebrospinal meningitis (CSM) has regained interest with the use of capsular polysaccharides (or polyosides) of the meningococcus as specific immunizing agents. These compounds proved to be effective in the USA against meningitis caused by Neisseria meningitidis serotype C. This study considers whether the polysaccharides of the serotype A meningococcus, which is prevalent in the African CSM belt, could be protective in epidemic conditions. Taking advantage of the usual seasonal peak of CSM cases, controlled field trials were undertaken in the Sudan early in 1973. 21 640 persons were vaccinated, half of them with a meningococcal polyoside A vaccine and the other half with tetanus toxoid as a placebo. In the former group there were no cases of meningitis, whereas in the latter 10 cases were reported, of which 7 were confirmed by laboratory tests. These studies indicate that the meningococcal polyoside A vaccine is efficient in epidemic conditions and could be used to control outbreaks of meningococcal meningitis. PMID- 4211057 TI - Comparison of indirect haemagglutination and immunofluorescence tests for malaria antibody in Aotus monkeys infected with Plasmodium falciparum. Application of indirect haemagglutination tests for malaria. AB - Longitudinal observations were made on 6 Aotus monkeys repeatedly infected with Plasmodium falciparum (West African and Palo Alto strains). Immunofluorescence titres were higher than indirect haemagglutination titres in the primary phase of the infections. Both serological tests were consistently positive later in the infections. Precipitins were often not detectable even during episodes of parasitaemia. PMID- 4211058 TI - Application of the indirect haemagglutination test for malaria: reproducibility with Plasmodium falciparum-sensitized cells. AB - The reproducibility of the IHA test was assessed. Two batches of glutaraldehyde fixed sheep cells were used and the cells were sensitized with different batches of P. falciparum antigen obtained from 4 owl monkeys. At the individual level the IHA test appears to have a reproducibility of approximately 90%. PMID- 4211059 TI - [Characterization of various cells of the fox pituitary gland by immunofluorescence on semi-fine sections and superposition of electron microscopy data]. PMID- 4211060 TI - [Study of the volume of spherical particles from an aleatory section]. PMID- 4211061 TI - [Ultrastructural observations on the supra-chiasmatic nuclei of normal, castrate and colchicinized rats]. PMID- 4211062 TI - [Course of the plasma level of testosterone during fetal life in the domestic swine (Sus scrofa L.)]. PMID- 4211063 TI - [Molecular aging of human glucose-6-phosphate dehydrogenase]. PMID- 4211064 TI - [Antagonist action of hexamethonium on acetylcholinesterase inhibition by tetrapropylammonium ion]. PMID- 4211065 TI - [Study of scorpion hemocyanin by circular dichroism]. PMID- 4211066 TI - [Increasing of the 5-alpha-steroid reductase activity of purified cell nuclei from the pituitary gland of castrate male rats]. PMID- 4211067 TI - [Study of the influence of the conformation and the 3d orbitals of sulfur on the electronic properties of anti-bacterial compounds of N-phenylsulfanilamide type]. PMID- 4211068 TI - [Dynamic characteristics of interactions between the micropredator Bdellovibrio bacteriovorus and the bacterium-host as a function of their relative initial densities]. PMID- 4211069 TI - [Study of immune reactions in the amphibian urodele Salamandra salamandra L. Modality of the graft reject reaction]. PMID- 4211070 TI - [Limits of geographical hematology: ethnological hematology]. PMID- 4211071 TI - Tooth root abscess and fistula in the squirrel monkey (Saimiri sciureus). PMID- 4211072 TI - [Alpha1-fetoprotein in some liver diseases (author's transl)]. PMID- 4211073 TI - [200 cases of psoriasis treated with Chinese medicine]. PMID- 4211075 TI - [Effect of streptomycin glycyrrhizinate on vestibular function and some other pharmacologic activities]. PMID- 4211074 TI - [Observation on the effect of camptothecin-dimethyl sulfoxide solution on psoriasis]. PMID- 4211076 TI - [Certain clinical and electrocardiographic features of angina decubitus]. PMID- 4211077 TI - [Clinical observations of 530 cases of snake bite treated with antivenin of Agkistrodon halys (Pallas)]. PMID- 4211079 TI - [Brachial plexus block via cervical route: report of 436 cases]. PMID- 4211078 TI - [Clinical analysis of 150 cases of Agkistrodon halys (Palas) bite]. PMID- 4211080 TI - [Toxicity of securinine and comparison with strychnine]. PMID- 4211081 TI - [Preliminary summary on the clinical experience with treatment of 77 cases of explosion deafness]. PMID- 4211082 TI - [Lethal granuloma]. PMID- 4211084 TI - [Abstract of the symposium on immunology of psoriasis]. PMID- 4211083 TI - [Effect of shengmaisan on cardiac arrest due to acute hemorrhage]. PMID- 4211085 TI - [Some developments in psoriasis research abroad]. PMID- 4211086 TI - [Clinicopathological conference: No 14-Spreading of redness and scaliness of the skin from the knees to the whole body]. PMID- 4211087 TI - Sustained effects of nitroglycerin ointment in patients with angina pectoris. PMID- 4211088 TI - Biotransformation of diethyl ether and chloroform. PMID- 4211089 TI - Three pregnancy-associated human plasma proteins: purification, monospecific antisera and immunological indentification. PMID- 4211090 TI - [Treatment of rheumatoid arthritis using D-penicillamine]. PMID- 4211091 TI - The recovery of indicator bacteria on selective media. PMID- 4211092 TI - Studies on the mechanism of the sporicidal action of glutaraldehyde. PMID- 4211093 TI - [Preliminary results of endocrine investigations in postmenopausal osteoporosis (author's transl)]. PMID- 4211095 TI - Studies on the group-specific polysaccharide of Neisseria meningitidis serogroup X and an improved procedure for its isolation. PMID- 4211094 TI - Characterization of pesticin. Separation of antibacterial activities. PMID- 4211096 TI - Biosynthesis of peptidoglycan in the one million molecular weight range by membrane preparations from Bacillus megaterium. PMID- 4211097 TI - Synthesis of cross-linked peptidoglycan attached to previously formed cell wall by toluene-treated cells of Bacillus megaterium. PMID- 4211098 TI - Characterization of the forssman glycolipid hapten of horse kidney by mass spectrometry. PMID- 4211099 TI - Purification and characterization of the thermophilic D-alanine carboxypeptidase from membranes of Bacillus stearothermophilus. PMID- 4211100 TI - Principles of parenteral alimentation. PMID- 4211102 TI - Radiation therapy in Hodgkin's disease. PMID- 4211101 TI - Unitary responses in frog olfactory epithelium to sterically related molecules at low concentrations. AB - Responses of receptor cells in the frog's olfactory epithelium were recorded using platinum-black metal-filled microelectrodes. Spontaneous activity varied over a wide range from 0.07 to 1.8 spikes/s. Mean interspike intervals ranged from 13.7 to 0.5 s. Excitatory responses to six sterically related compounds at low concentrations were investigated. Stimuli were delivered in an aqueous medium. Thresholds for impulse initiation varied from greater than 1 mM down to the nanomolar concentration range. Thresholds of different olfactory receptors to the same stimulus could vary by several log units. Thresholds of the same receptor cell to different stimuli could be within the same order of magnitude, or could vary by as much as 5 log units. Based upon quantitative measures of stimulus-evoked excitatory responses it appeared that some receptors did not discriminate among sterically related molecules, whereas other receptors clearly discriminated between stimuli which evoke similar odor sensations. PMID- 4211103 TI - [Psychodynamics of a paranoid psychosis following heterologous insemination]. PMID- 4211104 TI - [Assessment of sensitivity to penicillin and other antibiotics in Neisseria gonorrhoeae in Poland in 1973]. PMID- 4211105 TI - [Parenteral feeding]. PMID- 4211106 TI - [A case of allergic vascularitis]. PMID- 4211108 TI - [Correlation between results of slightly positive direct examination and of cultures in the diagnosis of tuberculosis]. PMID- 4211107 TI - Utilization of thioridazine combined with hydergine in the treatment of incipient mental disturbances in cerebral atherosclerosis. PMID- 4211109 TI - [Comparative passive electrical and light and electron microscopical investigations on the model of autolysis of the liver tissue (author's transl)]. PMID- 4211110 TI - [Polarization optical investigation on the isolated tubular basal membranes of the pig kidney (author's transl)]. PMID- 4211111 TI - Vitellogenetic processes and cytochemical aspects in the growing oocytes of the bentonic teleost Mugil chelo CUV. PMID- 4211112 TI - [Investigations for immune histochemical evidence in insulin, glucagon, and gastrin in isolated islets of Langerhans of the rat and mouse (author's transl)]. PMID- 4211113 TI - [Immune histochemical evidence of insulin and glucagon in cultivated islets of Langerhans in the rat (author's transl)]. PMID- 4211114 TI - Ultrastructural cytochemical study of acid phosphatase in bovine ruminal epithelium. PMID- 4211115 TI - [Histotopochemical investations on the islets of langerhans of the pancreas from fetal and newborn Wistar-rats. A contribution to the development of the rat isle (author's transl)]. PMID- 4211116 TI - Alkaline phosphatase activity in differentiating liver of chick. A histochemical and quantitative study. PMID- 4211117 TI - [Immune histochemical evidence of insulin in the islets of Langerhans of the rat after truncular subdiaphragmal vagotomy (author's transl)]. PMID- 4211118 TI - [Fluorescence optical evidence of carbonyl groups with acid hydrazides (author's transl)]. PMID- 4211119 TI - Histochemical studies on the chorioid plexuses of the goat embryos. 3. Histochemical distribution of acid and alkaline phosphatases. PMID- 4211120 TI - A histochemical study of some aspects of the metabolism of glutamic acid in the cerebellum of mammals. PMID- 4211121 TI - [About the interpretation and mathematical model of histochemical results by stochastical procedure with the QUANTIMET. I. Base for a mathematical model (author's transl)]. PMID- 4211122 TI - Demonstration and interspecies cross-sensitization of reaginic antibodies in dogs infected with Dirofilaria immitis. PMID- 4211124 TI - Exoerythrocytic stages of Plasmodium vivax in Ateles monkeys. PMID- 4211123 TI - Scrub typhus in eastern Taiwan, 1970. PMID- 4211125 TI - On the interaction of Ricinus communis lectin with plant amyloids. PMID- 4211126 TI - [Antibodies of the specificities anti-CW-anti D]. PMID- 4211127 TI - [Fibrillary centers of the nucleoli of Ehrlich's tumor cells]. PMID- 4211128 TI - [Electrophoretic study of the proteins in sheep uterine secretions at the onset of gestation]. PMID- 4211129 TI - [Circulating glucocorticosteroids in the rabbit and their nycthemeral fluctuations]. PMID- 4211130 TI - [Influence of stress on cholesterol 7 alpha-hydroxylase activity]. PMID- 4211131 TI - [Morphological distinction of thymus-dependent and independent lymphocytes in the mouse. In vitro analytical and preparative differential experiments]. PMID- 4211132 TI - [5-year analysis of a strain of mammary adenocarcinoma malignancy, structure, viral particles]. PMID- 4211133 TI - [Our experiences in the treatment of malignant tonsillar neoplasms]. PMID- 4211134 TI - [Late results in the treatment of malignant neoplasms of the tonsillar region]. PMID- 4211135 TI - [Preparation Intal in the treatment of children's bronchial asthma]. PMID- 4211137 TI - A new topical steroid-antibiotic combination, diprogenta. PMID- 4211136 TI - Electroimmunodiffusion of IgG heavy chains in nanogram quantities with a carboxymethyl-cellulose-agarose gel. PMID- 4211139 TI - Improvement of long-standing ventricular premature beats following prednisone therapy. PMID- 4211138 TI - A multicentric trial of a new steroid, betamethasone benzoate, in common dermatological disorders. PMID- 4211140 TI - Long-term safety of Nefopam hydrochloride (Acupan), a new analgesic formulation. PMID- 4211141 TI - A clinical evaluation of nefopam hydrochloride (Acupan): a new analgesic. PMID- 4211142 TI - An evaluation of the effectiveness of simethicone in acute upper gastrointesinal distress. PMID- 4211143 TI - Glaziovine versus diazepam: a double-blind clinical trial. PMID- 4211144 TI - A pilot study of ORF 8063, a new benzodiazepine in anxious alcoholic patients. PMID- 4211145 TI - Methylphenidate in children with minimal brain dysfunction: effects on attention span, visual-motor skills, and behavior. PMID- 4211146 TI - Clinical and computerized EEG effects of U-31,920, a new anxiolytic. PMID- 4211147 TI - Vitamin C prophylaxis and some problems of statistical inference. PMID- 4211148 TI - Nicotinic acid plasma concentrations after ingestion of 1,3,4,6-tetranicotinoyl fructo-furanose (tetranicotinoylfructose, nicofuranose). PMID- 4211149 TI - Physiology of spores of mycobacillin producer and non-producer mutants of Bacillus sbutilis. PMID- 4211150 TI - Respiration and metabolic processes of bacteria in autoclaved and gamma irradiated soil. PMID- 4211151 TI - An effect of centromere function on the behavior of ring-X chromosomes in Drosophila melanogaster. AB - It is shown that under the influence of an autosomal meiotic mutant that causes abnormalities in meiotic centromere function (mei-S332), ring-X chromosomes are frequently nonrecoverable. Evidence is presented that this nonrecoverability is caused by a failure of sister ring-chromatids to successfully effect an equational separation with resultant dominant lethality. Because mei-S332 results in meiotic abnormalities only after replication has been completed, and because ring chromosomes are normally transmitted with approximately the same efficiency as rod chromosomes, it is suggested that during replication in normal meioses, sister ring-chromatids form mutually interlocked ring complexes that are resolved without genetic consequences at anaphase II, with the resolution owing at least in part to normal centromere function. PMID- 4211152 TI - Microdifferentiation in a natural population of Drosophila melanogaster to alcohol in the environment. AB - Strains of D. melanogaster derived from a vineyard population were more resistant to alcohol in the environment than strains from a population derived from an area removed from the vineyard. Within the vineyard population those strains most closely associated with alcohol in the environment in the cellar were more resistant than those collected outside the cellar. There was evidence of gene flow between the inside and outside cellar components of this population, but microdifferentiation had occurred within the cellar in spite of this. The adaptation appears to be independent of the ADH system and involves both additive and dominance genetic effects. D. simulans, a species not found in the cellar and susceptible to the presence of alcohol, showed no differentiation between vineyard and removed populations. PMID- 4211153 TI - Glycol methacrylate embedding in enzyme histochemistry: application to arthropode tissue incubated for demonstration of unspecific esterase and succinic dehydrogenase activity. PMID- 4211154 TI - Analysis for possible linkage between the loci for the Waardenburg syndrome and various blood groups and serological traits. PMID- 4211155 TI - A study of diabetes in relation to blood groups and cholesterol levels. PMID- 4211156 TI - The effects of chemical modification by N-bromosuccinimide of saccharifying alpha amylase from Bacillus subtilis on various substrates. PMID- 4211157 TI - Sensitivity of Escherichia coli to viral nucleic acid. 8. Idiosyncrasy of Ca2+ dependent competence for DNA. PMID- 4211158 TI - Subacute sepsis of the hip treated by antibiotics and cemented prosthesis. PMID- 4211159 TI - Precise evaluation of the reduction of severe ankle fractures. PMID- 4211160 TI - Effects of hemorrhage on regional blood flow distribution in dogs and primates. AB - The effects of hemorrhage on arterial pressure, blood flows, and resistances in the coronary, mesenteric, renal, and iliac beds of healthy, conscious dogs and intact, tranquilized baboons were studied. Mild nonhypotensive hemorrhage (14+/-2 ml/kg) increased heart rate and mesenteric and iliac resistances slightly but significantly, and decreased renal resistance (-13+/-2%). Moderate hypotensive hemorrhage, 26+/-2 ml/kg, reduced mean arterial pressure (-23+/-2 mm Hg) and blood flows to the mesenteric (-56+/-3%), iliac (-58+/-5%), and coronary (-39+/ 4%) vascular beds, and increased heart rate (+89+/-9 beats/min) and resistances in the mesenteric (+73+/-15%), iliac (+102+/-19%), and coronary (+27+/-5%) beds. In contrast to the other beds, renal flow rose 11+/-6% above control and renal resistance fell 31+/-2% below control. Renal vasodilatation with hemorrhage was also observed in five baboons. The increases in mesenteric and iliac resistances were blocked almost completely by phentolamine, while the increase in coronary resistance was only partially blocked by phentolamine. The renal dilatation was not blocked by phentolamine, propranolol, atropine, or tripelennamine, but was prevented by indomethacin, suggesting that this dilatation was mediated by a prostaglandin-like compound. Thus the peripheral vascular responses to hemorrhage involve intense vasoconstriction in the mesenteric and iliac beds. In the normal conscious dog and the intact, tranquilized primate, the renal bed does not share in the augmentation of total peripheral resistance with nonhypotensive and moderate hypotensive hemorrhage, but does with more severe hemorrhage. In fact, renal vasodilatation occurs with nonhypotensive or moderate hypotensive hemorrhage, which can be prevented by blockade of prostaglandin synthetase with indomethacin. PMID- 4211162 TI - Physiopathology of the cerebellum in the monkey. I. Origin of cerebellar afferent nervous fibers from the spinal cord and brain stem. PMID- 4211161 TI - Fatty acid-binding protein in small intestine. Identification, isolation, and evidence for its role in cellular fatty acid transport. AB - A soluble fatty acid-binding protein (FABP), mol wt approximately 12,000 is present in intestinal mucosa and other tissues that utilize fatty acids, including liver, myocardium, adipose, and kidney. This protein binds long chain fatty acids both in vivo and in vitro.FABP was isolated from rat intestine by gel filtration and isoelectric focusing. It showed a reaction of complete immunochemical identity with proteins in the 12,000 mol wt fatty acid-binding fractions of liver, myocardium, and adipose tissue supernates. (The presence of immunochemically nonidentical 12,000 mol wt FABP in these tissues is not excluded.) By quantitative radial immunodiffusion, supernatant FABP concentration in mucosa from proximal and middle thirds of jejuno-ileum significantly exceeded that in distal third, duodenum, and liver, expressed as micrograms per milligram soluble protein, micrograms per gram DNA, and micrograms per gram tissue. FABP concentration in villi was approximately three times greater than in crypts. Small quantities of FABP were present in washed nuclei-cell membrane, mitochondrial and microsomal fractions. However, the amount of FABP solubilized per milligram membrane protein was similar for all particulate fractions, and total membrane-associated FABP was only about 16% of supernatant FABP. Intestinal FABP concentration was significantly greater in animals maintained on high fat diets than on low fat; saturated and unsaturated fat diets did not differ greatly in this regard.The preponderance of FABP in villi from proximal and middle intestine, its ability to bind fatty acids in vivo as well as in vitro, and its response to changes in dietary fat intake support the concept that this protein participates in cellular fatty acid transport during fat absorption. Identical or closely related 12,000 mol wt proteins may serve similar functions in other tissues. PMID- 4211163 TI - Physiopathology of the cerebellum in the monkey. 2. Motor disturbances associated with partial and complete destruction of cerebellar structures. PMID- 4211164 TI - Effects of d-amphetamine, morphine and chlorpromazine on responding under fixed interval schedules of food presentation or electric shock presentation. PMID- 4211165 TI - Mechanism of the vasoconstrictor action of prostaglandin B. PMID- 4211166 TI - In vitro synthesis of adenovirus core proteins. AB - mRNA extracted from polysomes of KB cells at late stages of productive infection with adenovirus type 2 was translated in a cell-free system derived from Krebs II ascites cells. Two of the polypeptides obtained in this reaction corresponded to the adenovirus core protein V and the precursor to core protein VII. The following criteria were used to establish identity between the in vitro products and the virion proteins: comigration during sodium dodecyl sulfatepolyacrylamide gel electrophoresis, cochromatography in sodium dodecyl sulfate-hydroxyapatite, specific immunoprecipitation of the precursor to core protein VII, and tryptic peptide analysis. PMID- 4211168 TI - Bacillus subtilis bacteriophage SP01, SP82, and phi e require host lysyl- and tryptophanyl-tRNA synthetases for phage development. AB - Infection of Bacillus subtilis mutants having temperature-sensitive lysyl- or tryptophanyl-tRNA synthetases with bacteriophage SP01, SP82, or phie indicates that both host enzymes are essential for phage development. No apparent modification of the temperature-sensitive phenotype of the mutant host enzymes occurs during phage infection. PMID- 4211167 TI - Transformation potentials of the noninfectious (defective) component in pools of adenoviruses type 12 and simian adenovirus 7. AB - Pools of adenovirus 12 and simian adenovirus 7 were separated into four or five fractions by density gradient centrifugation in cesium chloride. Each fraction was analyzed for total in vitro infectivity units, total transformation activity, and for total virus particle (VP) content. Two major subpopulations were separated with mean densities of 1.30 +/- 0.02 and 1.34 +/- 0.02 g/ml, respectively. Virions in the 1.34 g/ml range were highly infectious (10(2) to 10(3) VP per infectivity unit) in contrast to virions at 1.30 g/ml density (10(4) to 10(5) VP per infectivity units). Transformation capacity was evenly distributed throughout fractions of both viruses, indicating that genetically incomplete or defective virus particles were not deficient in their ability to induce transformation. The average VP per transformation unit for adenovirus 12 (2.85 x 10(6)) and for simian adenovirus 7 (4.00 x 10(6)) did not vary significantly from fraction to fraction. These values were obtained with optimal input multiplicities of 16 to 64 VP per cell. At higher multiplicities the apparent increase in VP per transformation unit was attributable to the viral cytocidal effect on hamster cells. These studies revealed that quantitation of in vitro transformation based on VP multiplicities was more reliable than on the basis of infectious units. These estimates were independent of method of virus production, extraction, and purification. PMID- 4211169 TI - Isolation of Yersinia enterocolitica from monkeys and deers. PMID- 4211170 TI - Antitubular basement-membrane antibodies in methicillin-associated interstitial nephritis. PMID- 4211171 TI - [Determination of serum immunoglobulins (IgA, IgM, IgG, IgE) during chronic bronchial infection]. PMID- 4211173 TI - [Modified Roiron medium in laboratory diagnosis of gonorrhea]. PMID- 4211172 TI - [Bacteriological characteristics of chronic bronchial infections]. PMID- 4211174 TI - The behavioral pharmacology of Sch 12679. A new psychoactive agent. PMID- 4211175 TI - [Unusual clinical and x-ray picture of an urethral diverticulum]. PMID- 4211176 TI - Compensating victims of violent crime. PMID- 4211177 TI - The fate of (14C)phenol in various species. PMID- 4211178 TI - Metabolism of 3-acetamido-6-methyl-8-n-propyl-s-triazolo (4,3-a)pyrazine (I.C.I. 58,301) in animals. PMID- 4211179 TI - The metabolism of sulphadimethoxypyrimidine. PMID- 4211180 TI - Folate binding in animal plasma. PMID- 4211181 TI - Turnover of lysozyme-positive monocytes in normal rat blood. PMID- 4211182 TI - Globin chain synthesis in sickle cell trait under conditions of folate antagonism. PMID- 4211183 TI - First report of Hb E in Italy. PMID- 4211184 TI - Disodium cromoglycate in the treatment of allergic asthma. PMID- 4211185 TI - A rapid screening test for detection of alpha-1 fetoprotein as an indicator of fetal distress. PMID- 4211186 TI - Family with a high activity of serum diamine oxidase. PMID- 4211187 TI - The eyes of embryos with chromosome abnormalities. PMID- 4211188 TI - Ocular histopathology of Norrie's disease. PMID- 4211189 TI - Experimental retinal detachment in the owl monkey. 11. The role of light in photoreceptor atrophy. PMID- 4211190 TI - Corneal cryopreservation and the fate of corneal cells in penetrating keratoplasty. PMID- 4211191 TI - Retinal degeneration in a baboon. PMID- 4211192 TI - Effect of nitrous oxide on air in vitreous. PMID- 4211193 TI - An evaluation of tobramycin in experimental corneal ulcers. PMID- 4211194 TI - [Edematous forms of pulmonary embolism: indication for assisted ventilation]. PMID- 4211195 TI - [Simultaneous study of myocardial perfusion flow and O2 and CO2 pressures]. PMID- 4211196 TI - [Peculiarities of atrio-ventricular conduction in a case of Wolff-Parkinson-White syndrome]. PMID- 4211197 TI - [Tachycardia by branch-to-branch reentry]. PMID- 4211198 TI - [Reciprocal tachycardia of prolonged course in children]. PMID- 4211199 TI - [Bidirectional tachycardia originating in the bundle of His]. PMID- 4211200 TI - [A case of bi-directional ventricular tachycardia caused by digitalis intoxication]. PMID- 4211201 TI - [37 years of effort angina pectoris in a case of aortic stenosis. Major deficiency of lactate dehydrogenase 1 and 2 isoenzymes]. PMID- 4211202 TI - [Double-inlet right ventricle: study of an anatomical-clinical case]. PMID- 4211203 TI - [Patent ductus arteriosus combined with pulmonary valve stenosis (with an intact interventricular septum)]. PMID- 4211205 TI - [Criteria of severity in acute pulmonary embolism]. PMID- 4211204 TI - [Injectable diphenylhydantoin in cardiology. Experimental study]. PMID- 4211206 TI - Population ecology of Sulfolobus acidocaldarius. II. Immunoecolgical studies. PMID- 4211207 TI - Incorporation of labelled amino acids by nuclei isolated from Euglena gracilis. PMID- 4211208 TI - Inhibition of carotenoid synthesis in Myxococcus fulvus (Myxobacterales). PMID- 4211209 TI - Mixed carbon source effect in the phenazine-alpha-carboxylic acid synthesis and the aromatic pathway in Pseudomonas spp. PMID- 4211210 TI - Isolation, enumeration, and host range of marine Bdellovibrios. PMID- 4211212 TI - Formation and regeneration of Penicillium chrysogenum protoplasts. PMID- 4211211 TI - Endocytosis and the adaptive acid hydrolases in Tetrahymena pyriformis GL. PMID- 4211213 TI - In vivo survival of cryopreserved endothelial cells in primates. PMID- 4211214 TI - Intravitreal injection of dexamethasone. Treatment of experimentally induced endophthalmitis. PMID- 4211215 TI - [Further observations on some gastrointestinal effects of 3,3-dihydroxydibutyl ether]. PMID- 4211216 TI - Effect of prostaglandin E1 administration on the heart glycogen synthase and phosphorylase systems. PMID- 4211217 TI - Oxidative phosphorylation and respiration by liver mitochondria from polychlorinated biphenyl-intoxicated rats. PMID- 4211219 TI - Acid denaturation of bovine carbonic anhydrase B. PMID- 4211218 TI - N-methylation of biogenic amines. I. Characterization and properties of an N methyltransferase in rat brain using 5-methyltetrahydrofolic acid as the methyl donor. PMID- 4211220 TI - Structure of the mannan form Saccharomyces strain FH4C, a mutant constitutive for invertase biosynthesis. I. Significance of phosphate to the structure and refractoriness of the molecule. PMID- 4211221 TI - Reserpine as an uncoupling agent. PMID- 4211222 TI - Occurrence of trans-phytoene in microorganisms grown in the absence of carotenogenesis inhibitors. PMID- 4211223 TI - Genes and isoenzymes controlling the first step in the aromatic amino acid biosynthesis in Schizosaccharomyces pombe. PMID- 4211224 TI - Bacterial citrate synthases: purification, molecular weight and kinetic mechanism. PMID- 4211225 TI - Studies of substrate hydrolysis by an esterase isozyme of rat serum. PMID- 4211226 TI - The electron microscopical structure of thyroglobulin obtained by micropuncture of rat thyroid follicles. PMID- 4211227 TI - The cells of origin of the corpus callosum in rat, cat and rhesus monkey. PMID- 4211228 TI - [10 asthmatic children treated by psychotherapeutic relaxation (Schultz-Sapiz method from adapted psychanalytic inspiration]. PMID- 4211229 TI - Peptides with NH2-terminal tryptophan in the adenohypophysis. A chemical and fluorescence histochemical study. PMID- 4211233 TI - Immunoglobulin classes in Xenopus laevis. PMID- 4211234 TI - Deviation and laterality of hand preference in monkeys. PMID- 4211235 TI - Reovirus infected cells for studying microtubules and spindle poisons. PMID- 4211236 TI - Identification of 4-chloro-4'-hydroxybiphenyl and 4,4'-dichloro-3-hydroxybiphenyl as metabolites of 4-chloro- and 4,4'-dichlorobiphenyl fed to rats. PMID- 4211237 TI - In vitro antibacterial activity of 2-amino-4(2-ethynyl-1-methyl-5-nitroimidazole) pyrimidine, a metronidazole derivative with antitrichomonad activity. PMID- 4211238 TI - Gold thioglucose induced terminal degeneration in mouse hypothalamus. PMID- 4211240 TI - [Sjogren's syndrome: serum proteins and autoimmune phenomena]. PMID- 4211239 TI - Effect of hemorrhage on electrical and PH gradients in the intact stomach of the subhuman primate. PMID- 4211241 TI - [Letter: Glucocorticoids in cavernous hemangiomas]. PMID- 4211242 TI - Opaque arthrography of the temporomandibular joint. PMID- 4211243 TI - An assessment of the use of prophylactic antibiotics in third molar surgery. PMID- 4211244 TI - Suicidal gunshot wounds resulting in severe maxillofacial injury. PMID- 4211245 TI - A desmoplastic fibroma in the mandible. PMID- 4211246 TI - Epithelial cells in the periodontal membrane of teeth with and without periapical inflammation. PMID- 4211247 TI - Variation in ADH activity in class I and class II strains of Drosophila. PMID- 4211248 TI - Antigenic relationship between pseudomonas Bal-31 membranes and bacteriophage PM2. PMID- 4211249 TI - The kinetics of sodium transport in the toad urinary bladder. 3. The role of potassium. PMID- 4211250 TI - [Association of nephrotic syndrome and bronchial cancer]. PMID- 4211251 TI - Cerebrospinal fluid flow and iodide 131 transport in the spinal subarachnoid space. PMID- 4211253 TI - Endplate currents are shortened by octanol: possible role of membrane lipid. PMID- 4211252 TI - Thyrotropin releasing hormine (TRH): distribution in the brain, blood and urine of the rat. PMID- 4211255 TI - [Results of reduction of bland struma by treatment with 131-I in endemic goiter area of Southern Bavaria (author's transl)]. PMID- 4211254 TI - [Clinical and biochemical differences in the course of infectious hepatitis and serum hepatitis (author's transl)]. PMID- 4211256 TI - [Health education through medical check-up]. PMID- 4211257 TI - [The effect of oxyfedrine on cardiodynamics in halothane anesthesia (author's transl)]. PMID- 4211258 TI - [Local corticosteroid therapy of degenerative diseases of joints and tendons (author's transl)]. PMID- 4211259 TI - [Physical exercises and sport]. PMID- 4211260 TI - [Proceedings: Nonmedicamentous therapy of heart insufficiency]. PMID- 4211262 TI - [Proceedings: Early closure of the prolabium in piercing cleft lip, jaw, and palate]. PMID- 4211261 TI - [Proceedings: Sexuality of adolescents]. PMID- 4211263 TI - [Proceedings: Endothelial lesions caused through the preparation of great saphenous vein for venous bypass]. PMID- 4211264 TI - [Proceedings: Diagnosis of benign and malignant skeleton diseases]. PMID- 4211266 TI - [Experimental tuberculous infection produced by the system phage-Mycobacterium]. PMID- 4211265 TI - Aflatoxins in foods and feedstuffs. 2. Determination of the aflatoxin B1, B2, G1 And G2 contents in grain crops. PMID- 4211267 TI - [Actinomycin D as an agent preventing the development of resistance in Myocobacterium tuberculosis]. PMID- 4211268 TI - Quantitation of bovine liver catalase by single radial immunodiffusion. PMID- 4211269 TI - Endontics in a capuchin monkey: reduction in the length of the canine crown. PMID- 4211270 TI - [Contamination of waters through organic trace substances. Hygienic significance of chemical and biological analytic results on organic trace substances with short half-life as demonstrated on the example of organophosphorous pesticides]. PMID- 4211271 TI - High voltage electron microscopy on microgametogenesis of Haemoproteus columbae. PMID- 4211272 TI - 'Coupled transglucuronidation': a new tool for studying the latency of UDP glucuronyl transferase. PMID- 4211273 TI - [A case of Recklinghausen's disease with concommittant polyposis of the small intestine (author's transl)]. PMID- 4211274 TI - [A method for the vectorial ECG evaluation in the horse]. PMID- 4211275 TI - [A method of isotope tracing and microlocalization of lithium]. PMID- 4211276 TI - [A new antitumor compound: hydroxy-9 ellipticin. Effect on mouse L 1210 leukemia]. PMID- 4211277 TI - [A simple technic for chromosome preparations of cells cultured in vitro from small quantities of human blood]. PMID- 4211278 TI - [A stereotaxic platform technique (author's transl)]. PMID- 4211279 TI - [Abdominal surgery without routine gastric decompression, intravenous infusion and fasting. Analysis of 250 cases of subtotal gastrectomy]. PMID- 4211280 TI - [Abnormal personality. 2. The gap between the normal population and abnormal patients]. PMID- 4211281 TI - [Abnormal thyroxine and triiodothyronine concentration in the blood due to familial disorders in the thyroxine-binding globulin concentration]. PMID- 4211282 TI - [Action of a hypoglycemic agent found in the young bark of Eugenia jambolania(Myrtacea) on induced hyperglycemia of the rabbit and continuation of its purification]. PMID- 4211283 TI - [Action of a pentacyclic triterpenoid, asiaticoside, isolated from Hydrocotyle masagascariensis or Centella asiatica, against gastric ulceration in the Wistar rat exposed to cold at 2 degrees C]. PMID- 4211284 TI - [Action of a phospholipid bacterial extract on splenic lymphocytes of mice]. PMID- 4211285 TI - [Action of various progestational hormones on the electric activity of the rat myometrium in pregnancy after biovariectomy]. PMID- 4211287 TI - [Acupuncture analgesia following bilateral adrenalectomy and cervical sympathectomy in rabbits]. PMID- 4211286 TI - [Activation of the adrenal cortex in the newborn rat]. PMID- 4211288 TI - [Adjuvant activity of monomeric fractions of bacterial peptidoglycans in delayed hypersensitivity]. PMID- 4211289 TI - [Adjuvant activity of peptidoglyoans from mycobacteria]. PMID- 4211290 TI - [Affinity of murin interferon for concanavalin A]. PMID- 4211291 TI - [Agar electrophoretic demonstration of proteolytic activities in extracts from porcine gastric mucosa]. PMID- 4211292 TI - [Agrimophol structure--the taenifugal constituent from root-sprout of Agrimonia pilosa ledeb]. PMID- 4211293 TI - [Alpha-fetoproteins and testicular tumors]. PMID- 4211294 TI - [An invasive neoplasm from embryonic cells of Drosophila melanogaster cultured permanently in vivo (author's transl)]. PMID- 4211295 TI - [An investigation about the applicability of paraffin-embedded tissue as a substratum for the demonstration of antinuclear factors by means of immunfluorescence (author's transl)]. PMID- 4211296 TI - [Analysis of rheoencephalography in 322 normal adults]. PMID- 4211297 TI - [Angioscintigraphy and angiography in the study of vascular and cerebral pharmacodynamics]. PMID- 4211299 TI - [Anti-epileptic treatment supervision in an Medico-Pedagogic-Institute for average mental retardation]. PMID- 4211298 TI - [Animal experiments on the effect of viruses on wound healing (author's transl)]. PMID- 4211300 TI - [Antibacterial activity of a new semisynthetic aminoglycoside antibiotic amikacin (BB-K8) (author's transl)]. PMID- 4211301 TI - [Antibiotic from Bac. cereus var. mycoides. 1]. PMID- 4211303 TI - [Anxiety of patients with breast cancer]. PMID- 4211302 TI - [Antimycobacterial effect of ethambutol and rifampin in vitro and determination of sensitivity of Mycobacterium tuberculosis]. PMID- 4211304 TI - [Aortic muscular conus stenosis. A contribution on pathogenesis]. PMID- 4211305 TI - [Appendiceal diverticula]. PMID- 4211306 TI - [Applications of the electronic microprobe to the study of bone biomechanics]. PMID- 4211307 TI - [Arterial system of gastrointestinal tract in the toad (Bufo bufo)]. PMID- 4211308 TI - [Atmosphere and the human body]. PMID- 4211309 TI - [Autodifferentiation of the precardiac mesoderm of anourous amphibia in culture in vitro]. PMID- 4211310 TI - [Autoradiographic in-vitro investigations on the effect of duration of incubation in a glutamine-free culture medium on DNA synthesis in psoriatic epidermal cells obtained from punch biopsies (author's transl)]. PMID- 4211311 TI - [Autoradiography of steroid hormones, applied to cultured cells]. PMID- 4211312 TI - [Bacteremia, rheumatic fever and cardiovascular diseases]. PMID- 4211313 TI - [Bedside nursing. Bedside rehabilitation nursing of a patient with cerebral embolism]. PMID- 4211314 TI - [Bedside nursing. Nursing action in rehabilitation of a patient following amputation of a leg]. PMID- 4211315 TI - [Behavior of Staphylococcus aureus cell colonies in medium with streptomycin added]. PMID- 4211316 TI - [Biochemical diagnosis of Neisseria elongata (author's transl)]. PMID- 4211317 TI - [Biological activities of hydrosoluble adjuvants of low molecular weight isolated from Mycobacterium tuberculosis var. hominis]. PMID- 4211318 TI - [Blood circulation in the lower leg of patients with total AV block before and during pacemaker stimulation (author's transl)]. PMID- 4211319 TI - [Bone resorption after parabiosis in "op" (osteopetrosis) in rats]. PMID- 4211320 TI - [Can lyophilised dura mater be used for cardiac tissue replacement? (author's transl)]. PMID- 4211321 TI - [Catecholaminergic innervation of the hypothalamo-posthypophyseal system. High resolution radio-autographic study in the rat]. PMID- 4211322 TI - [Cerebellar melanosis in the swine]. PMID- 4211324 TI - [Changes in the development of a transplanted tumor under the influence of manipulations or the social experience of control mice living with the tumor bearing mice]. PMID- 4211323 TI - [Cerebral attacks of concealed cardiac origin (author's transl)]. PMID- 4211325 TI - [Changes induced by theophylline in vitro on the glycogen content, carbohydrate metabolism and finally on the phagocytic and bactericidal activity of polynuclear leukocytes]. PMID- 4211327 TI - [Chemotaxonomic searches on vascular plants. The 3, 5, 4' trihydroxy 7 methoxyflavone, isolated from Fibigia eriocarpa D.C. grains (Crucifers)]. PMID- 4211326 TI - [Chemical and structural study of 5 beta-androstane 3 alpha-ol-7,17-dione]. PMID- 4211328 TI - [Chromosomal location of the N prophage in Salmonella montevideo (under-group C1)]. PMID- 4211329 TI - [Chromosome mutations in human leukocytes and the test-system problem in the analysis of the mutagenicity of biosphere factors]. PMID- 4211330 TI - [Clearance determination within the scope of renal radioisotope diagnosis]. PMID- 4211331 TI - [Clinical analysis of 286 cases of pediatric high altitude heart diseases]. PMID- 4211332 TI - [Clinical anatomic and histopathological study of ocular signs in 2 cases of mosaicism associated with autosomal 18-21 double trisomy]. PMID- 4211333 TI - [Clinical application of a new biophysical method based on the isotopic analysis of CO2 exhaled by man]. PMID- 4211334 TI - [Clinical application of ketamine anesthesia]. PMID- 4211335 TI - [Clinical conference: Failure in understanding needs of a patient following total pharyngectomy]. PMID- 4211336 TI - [Clinical experiences with fast neutron therapy of cancer (author's transl)]. PMID- 4211337 TI - [Clinical features of brucellosis in pregnancy (author's transl)]. PMID- 4211338 TI - [Clinical picture and differential diagnosis of diverticulosis (author's transl)]. PMID- 4211339 TI - [Clinical studies on Intal in the treatment of patients with bronchial asthma]. PMID- 4211340 TI - [Clinical study of agrimony treatment in taeniasis]. PMID- 4211341 TI - [Clinical study of pulmonary purification in the monkey and dog]. PMID- 4211342 TI - [Clinical study on the effect of corticosteroid-antibiotic compound in the prevention and treatment of acute apical periodontitis]. PMID- 4211343 TI - [Clinical trials of phenoxymethylpenicillin in O.R.L]. PMID- 4211344 TI - [Clinico pathological conference. Case 15--prolonged fever, hepatomegaly, jaundice and coma]. PMID- 4211345 TI - [Clinico-statistical contribution to cases of Rh isoimmunization at the Obstetric and Gynecologic Clinic of Padua from the year 1968 to 1972]. PMID- 4211346 TI - [Clinicopathological conference. No. 16. Fever, right-upper side abdominal pain, hepatomegaly]. PMID- 4211347 TI - [Clinicopathological conference. No. 17. Development of acute upper abdominal pain in 3 occasions and laparotomy repeated 3 times within 18 months following gastrectomy]. PMID- 4211348 TI - [Coagulation inhibitory factor: antithrombin--with special reference to antithrombin 3]. PMID- 4211349 TI - [Combined drug therapy in highly acute attacks of pain in the course of rheumatic diseases]. PMID- 4211350 TI - [Comments on relationship between auxilliary personnel and patient during long term hospitalization]. PMID- 4211351 TI - [Comparative anatomy of the urterial system of the leg]. PMID- 4211352 TI - [Comparative characteristics of the mutagenic effect of N-nitroso-N-methylbiuret and UV rays on a culture of Penicillium chrysogenum]. PMID- 4211353 TI - [Comparative evaluation of certain methods of detection of Mycobacterium tuberculosis in tuberculotic patients with negative results of bacteriscopy]. PMID- 4211354 TI - [Comparative evaluation of diagnostic methods in placental insufficiency]. PMID- 4211355 TI - [Comparative examinations on the normal distribution of immune globulins in human serum and aqueous humor (author's transl)]. PMID- 4211356 TI - [Comparative micromorphology of the esophagus in various vertebrates]. PMID- 4211357 TI - [Comparative studies on susceptibility to antibiotics of strains of Neisseria gonorrhoeae isolated in 1962-1963, 1970 and 1971]. PMID- 4211358 TI - [Comparative study of several animal ceruloplasmins obtained by a new preparation technic]. PMID- 4211359 TI - [Comparative study of the concentrations of 23 antigens in a group of apparently normal subjects and in a group of patients with Hodgkin's disease]. PMID- 4211360 TI - [Comparative toxicity (mammals, insects, acarians) of new trisubstituted derivatives of thiophosphoric acid]. PMID- 4211361 TI - [Comparison of antibacterial activity of cephapirin with cephalothin and cephaloridine to various pathogenic bacteria recently isolated from clinical materials (author's transl)]. PMID- 4211362 TI - [Composition of ancient proteins]. PMID- 4211363 TI - [Composition of the gases emitted by Clostridium sporogenes, Clostridium bifermentans, Clostridium sordelii, Clostridium oedematiens and Plectridium putrificum cultivated in medium with sodium thioglycolate, under vacuum, after alkalinization of the culture medium]. PMID- 4211364 TI - [Concomitant occurrence of hyper-thyroid crisis and ketoacidotic diabetic coma]. PMID- 4211365 TI - [Conditions allowing a longer survival and the reproduction of Psammomys (sand rat) kept in laboratory]. PMID- 4211366 TI - [Congenital megacolon (author's transl)]. PMID- 4211367 TI - [Conjunctival, retinal, and vitreous hemorrhages during long term anticoagulant treatment]. PMID- 4211368 TI - [Contemporary problems of diagnosis of gonorrhea]. PMID- 4211369 TI - [Continuous duodenal feeding. Attempted use in the newborn infant with low birth weight]. PMID- 4211370 TI - [Cord factor--its chemistry, biochemistry and immunochemistry]. PMID- 4211371 TI - [Correlation between the location of antigens detected by immunofluorescence and the ultrastructural stages of the morphogenesis of FV 3 (Frog Virus 3)]. PMID- 4211373 TI - [Cryotherapy of corneal ulcer]. PMID- 4211372 TI - [Correlations between chemical constitution and germicide effect. 27. Preparation and bacteriostatic effect of 2-ethylphenols]. PMID- 4211374 TI - [Current status of the knowledge of the effect of malnutrition on the genetic material]. PMID- 4211375 TI - [Cytomorphological studies on the cerebrospinal fluid in healthy dogs and in 7 cases with central nervous system diseases]. PMID- 4211376 TI - [Demonstration of a mass and a group effect in the appearance of sexual reproduction phases in the rotifer Notommata copeus]. PMID- 4211377 TI - [Demonstration of gap junctions or nexus by lanthanum in the brown fat of the European hamster (Cricetus cricetus)]. PMID- 4211378 TI - [Demonstration of 3 soluble proteases in E. coli]. PMID- 4211379 TI - [Demonstration, by comparison of semi-fine and ultra-fine successive sections, of cellular types other than glucagon cells in the endocrine pancreas of the teleostean fish Xiphophorus helleri H]. PMID- 4211380 TI - [Denaturation and the antigenic properties of the structural protein of the tobacco mosaic virus]. PMID- 4211381 TI - [Dentigerous cysts of the jaws. Report of 3 cases]. PMID- 4211382 TI - [Detection of N-epsilon, N-epsilon, N-epsilon-trimethyllysine in ribosomal protein L 11 by methylation of E. coli ribosomes synthesized in the presence of ethionine]. PMID- 4211383 TI - [Determination of enzymes of the urea cycle, glutaminase and asparaginase in cattle and pigs]. PMID- 4211384 TI - [Determination of gluocorticoid residues using a biological technic. 2. Cattle]. PMID- 4211385 TI - [Determination of possible corticosteroids in the brown fat of the European hamster (Cricetus cricetus). Identification of compounds isolated by gas chromatography and mass spectrum analysis]. PMID- 4211386 TI - [Determination of renal function by the single injection technic. Statistical analysis of the bicompartmental model proposed by Sapirstein]. PMID- 4211387 TI - [Determination of the adenosine triphosphate (ATP) content in an isolated cell]. PMID- 4211388 TI - [Development of the branching factor activity of fetal liver of rats during the gestation]. PMID- 4211390 TI - [Dietetics and prophylactic measures in hypertension (author's transl)]. PMID- 4211389 TI - [Diagnosis and treatment of nephroangiopathies in diabetes mellitus]. PMID- 4211391 TI - [Differential diagnosis of spondyloepiphyseal dysplasia]. PMID- 4211392 TI - [Differential diagnosis of the hypercalcemia syndrome (author's transl)]. PMID- 4211393 TI - [Discussion. The status of rehabilitation medicine in the United States]. PMID- 4211394 TI - [Disease forms of myoclonic-astatic petit mal]. PMID- 4211395 TI - [Distribution of 14C-carbocromen in the monkey brain]. PMID- 4211396 TI - [Dopamine release in the rat nigrostratum system after hydroxy-5 tryptophan administration]. PMID- 4211397 TI - [Drip infusion urography]. PMID- 4211398 TI - [Duality of Onchocerca volvulus in man and of O. sp. Cameron, 1928, in cattle. New species of bovine Onchocerca in Togo]. PMID- 4211399 TI - [Dyskalemia]. PMID- 4211400 TI - [Early postoperative gastrointestinal motility]. PMID- 4211401 TI - [Ectodermic origin of the derma of the face and neck, demonstrated by interspecific combinations in the bird embryo]. PMID- 4211402 TI - [Editorial: Pediatric surgery]. PMID- 4211403 TI - [Effect exerted by histones and comparatively by serotonin and bradykinin, on in vitro fibroblast culture]. PMID- 4211405 TI - [Effect of aeration on the formation of proteolytic enzymes by Bacillus megaterium]. PMID- 4211404 TI - [Effect of a change in the chemical structure of the thyrotropin releasing factor on the manifestation of its biological action]. PMID- 4211406 TI - [Effect of anabolic preparations on immunologic reactions of the body of rabbits and white mice]. PMID- 4211407 TI - [Effect of antineoplastic agents on the activity and molecular heterogeneity of lysosomal hydrolases in Ehrlich ascites tumor]. PMID- 4211408 TI - [Effect of bacterial cultures of Lactobacillus acidophilus (acidophilic milk) on the carrier state of Shigella and Salmonella organisms in children]. PMID- 4211409 TI - [Effect of feeding, fasting and phlorhizin diabetes on the relationship between free fatty acids and glucose in sheep blood]. PMID- 4211410 TI - [Effect of heat on rabbit spermatogenesis]. PMID- 4211411 TI - [Effect of magnesium ions on the genetic transformation process and the development of competence in Bacillus subtilis]. PMID- 4211412 TI - [Effect of murine and primate interferons on mouse-monkey hybrid cells]. PMID- 4211413 TI - [Effect of philtrum needling on organic blood flow in cats under hemorrhagic shock]. PMID- 4211414 TI - [Effect of salicylate on the nucleotide phenomenon or the so-called Laves-value]. PMID- 4211415 TI - [Effect of saturation of Mycobacterium tuberculosis--a theoretical basis of the method of mazimum concentration of tuberculostatic preparations]. PMID- 4211416 TI - [Effect of several mutagens on the inactivation of transforming DNA in vitro (author's transl)]. PMID- 4211417 TI - [Effect of the variations of oxygen concentration in the medium on cultured cardiac cells]. PMID- 4211418 TI - [Effects of ecdysone injection on the moulting and the metamorphosis of permanent larvae of Aeshna cyanea Mull. (Insect, Odonate)]. PMID- 4211419 TI - [Effects of lividomycin on bacillary dysentery and related disorders. Comparison with the effects of kanamycin by a double blind method]. PMID- 4211420 TI - [Efficiency and risk of mediastinoscopy (author's transl)]. PMID- 4211421 TI - [Electron microscopy studies of experimental tick-borne encephalitis]. PMID- 4211422 TI - [Electrophysiology of the cerebellar cortex in the staggerer mutant mouse]. PMID- 4211423 TI - [Elimination and metabolism of 7,12 dimethylbenz(a)anthracene (DMBA) after oral administration to normal and 3 methylcholanthrene(3-MC) pretreated mice]. PMID- 4211424 TI - [Elimination of atmospheric chlorine pollution in Shanghai Liaoyuan Chemical Factory and the study of its result]. PMID- 4211425 TI - [Embryopathic epilepsy]. PMID- 4211426 TI - [Endocardiosis of canine atrioventricular valves. IV. Electron microscopy studies]. PMID- 4211427 TI - [Endoscopic features of the incipient late stage of acid-induced corrosive burn of the stomach (author's transl)]. PMID- 4211428 TI - [Energy production during oocyte maturation in Xenopus laevis]. PMID- 4211429 TI - [Enhanced drug hydroxylation in man under diphenyl-hydantoin therapy]. PMID- 4211430 TI - [Enteric-resistent coatings with cellulose acetophtalate. 2. Relationship between film thickness and coating resistance in vivo]. PMID- 4211431 TI - [Epidemiological studies on outbreaks of food poisoning due to Escherichia coli 0124: K72: H-]. PMID- 4211432 TI - [Epidemiology and prevention of testicular tumors]. PMID- 4211433 TI - [Estrogen content of bovine serum and urine before, during and following normal delivery]. PMID- 4211434 TI - [Etiology and pathogenesis of hemorrhagic necrotic enteritis in an epidemic of bacillary dysentery]. PMID- 4211435 TI - [Evaluation of myocardial contractility using simultaneous recording of left ventricular pressure and apex cardiogram]. PMID- 4211436 TI - [Evaluation of the "open-negative syndrome in the clinical course of tuberculosis]. PMID- 4211438 TI - [Experimental observations on gastrointestinal motility and absorptive function after abdominal operation]. PMID- 4211439 TI - [Exsudative enteropathy in congenital intestinal lymphangiectasis with multiple skeletal changes]. PMID- 4211440 TI - [Eye manifestations in Turner's syndrome]. PMID- 4211437 TI - [Experimental lesions of the nervous and muscular systems due to chloroquine: models of various storage dystrophies (author's transl)]. PMID- 4211441 TI - [Factors of myocardial performance. Definitions and clinical implications]. PMID- 4211442 TI - [Food additives--saccharin]. PMID- 4211443 TI - [Fucheng lich'i tang instead of postoperative gastric decompression, intravenous infusion and fasting in gastric surgery]. PMID- 4211444 TI - [Functional and structural characteristics of the kidneys in diabetes mellitus (a radioisotope studies)]. PMID- 4211445 TI - [Further research on the retinohypothalamic nervous pathway in birds]. PMID- 4211446 TI - [Genesis and biochemistry of ruminant acidosis. 1. Starch, amylase activity and acidity]. PMID- 4211447 TI - [Genetic specificity of beta amylase in Triticum aestivum: existence of 5 types of zymograms]. PMID- 4211448 TI - [Group typing of streptococci with an agar immunodiffusion method]. PMID- 4211449 TI - [Health service development in light of economic statistics 1966-72]. PMID- 4211450 TI - [Hepatitis antigen B (HBAg) and hematologic diseases]. PMID- 4211451 TI - [Histochemical demonstration of carbonic anhydrase in the bovine forestomach and esophagus]. PMID- 4211452 TI - [Histogenesis of heart-base tumors in the dog. A histological, histochemical and electron-microscopy study]. PMID- 4211453 TI - [Histological and histometric changes in the adrenal glands of nonthriving piglets]. PMID- 4211454 TI - [How essential are the essential fatty acids?]. PMID- 4211455 TI - [How to advance antidiabetic therapy]. PMID- 4211456 TI - [Humoral immunity and resistance to acute meningococcal infections]. PMID- 4211458 TI - [Ideals and technics of rehabilitation. An interview]. PMID- 4211457 TI - [Hypophysiotropic synthetic neurosecretory substance: TRH. Clinical applications]. PMID- 4211459 TI - [Identification of specific NADH-diaphorase of placenta]. PMID- 4211461 TI - [Immunity component in sclerotic heart diseases (approach to the problem)]. PMID- 4211460 TI - [Ileus of the newborn in the region of the duodenum (author's transl)]. PMID- 4211462 TI - [Immuno-serological studies on Sashima hepatitis (infectious hepatitis)]. PMID- 4211463 TI - [Immunopathology of experimental and human chronic pyelonephritis; demonstration of bacterial antigen by immunofluorescence]. PMID- 4211464 TI - [Importance of radioimmunochemical determination of serum TSH and TRH test for diagnosis of thyroid diseases]. PMID- 4211465 TI - [Improvement an activity test of an antitoxic fraction drawn from several tissues and organs on alcoholic intoxication]. PMID- 4211466 TI - [In vitro and in vivo antibacterial activity of cephapirin (author's transl)]. PMID- 4211467 TI - [In vitro biosynthesis of progesterone by the human placenta. Kinetic study of pregnenolone sulfate penetration and metabolism]. PMID- 4211469 TI - [Incidence of pulmonary sarcoidosis after cure of cavernous bacteriologically positive pulmonary tuberculosis]. PMID- 4211468 TI - [In vitro inhibition of the blastogenesis of T lymphocytes by delta 9 tetrahydrocannabinol]. PMID- 4211470 TI - [Infection by Listeria monocytogenes]. PMID- 4211472 TI - [Influence in in vitro culture, of actinomycin D on the morphogenesis of the uropygial vesicle and on RNA distribution]. PMID- 4211471 TI - [Infectious pancreatic necrosis in Salmonidae: existence in the serum of undamaged trout of a 6 S molecule specifically neutralizing the virus]. PMID- 4211473 TI - [Influence of estradiol-17 beta and progesterone during induction by prolactin and growth hormone of lobulo-alveolar differentiation of mammary tissue of the pregnant ewe: study in organotypic culture]. PMID- 4211474 TI - [Influence of ultraviolet radiation on kinetic and nuclear infrastructure of Tetrahymena pyriformis]. PMID- 4211475 TI - [Influence of x-rays on the time of survival of Ceratitis capitata Wied in the total absence of food]. PMID- 4211476 TI - [Infraclavicular percutaneous catheterization of the subclavian vein]. PMID- 4211477 TI - [Inhibition of B. thuringiensis DNA-dependant RNA-polymerases by the B. thuringiensis exotoxin]. PMID- 4211478 TI - [Injuries caused by poisonous animals]. PMID- 4211479 TI - [Interaction of a biological preparation (Lysocorticone) against serotonin in vivo and against serotonin, bradykinin and prostaglandin in vitro]. PMID- 4211481 TI - [Intestinal transport in vitro of sodium and chlorine in the European flounder, Platichthys flesus, in seawater and fresh water]. PMID- 4211482 TI - [Introduction of foreign literature and discussion: "The difference caring makes" by Naugle EH, from AJN 73, 11, 1890-1, 1973]. PMID- 4211480 TI - [Interference phenomena on the osmiumtetroxide fixed specimen for systematic electronmicroscopical investigation (author's transl)]. PMID- 4211483 TI - [Investigations about an isolate of the chlorotic ringspot virus of Cherry (author's transl)]. PMID- 4211484 TI - [Is the malachite green broth according to Habs and Kirchner suitable for serving as an isolation medium for Pseudomonas aeruginosa from the water (author's transl)?]. PMID- 4211485 TI - [Isolation of hepatitis-B-antigen from water and sewage by means of immuno adsorption in a continuous flow procedure (author's transl)]. PMID- 4211487 TI - [Letter: Distribution of ABO and Rh blood groups in Dacca]. PMID- 4211486 TI - [Kidney auto-transplantation for the treatment of reno-vascular hypertension]. PMID- 4211488 TI - [Letter: Feces disinfection]. PMID- 4211489 TI - [Light and electron microscope studies on stages of Sarcocystis tenella in the intestine of cats. I. The oocysts and sporocysts (author's transl)]. PMID- 4211490 TI - [Lithium gluconate: systematic and factorial analysis of 104 cases which have been studied for 2 and one-half to 3 years in patients regularly observed and showing periodic cyclothymia or dysthymia]. PMID- 4211491 TI - [Liver cystathionase activity in the rat treated with 7-12 dimethylbenz(a)anthracene]. PMID- 4211492 TI - [Localization of spermatozoa in the oviduct of the ground salamander, Salamandra salamandra L. (Amphibia, Urodela) during fertilization]. PMID- 4211493 TI - [Long term efficacy and tolerance of antidiabetic treatments. New data]. PMID- 4211495 TI - [Mass experience in mosquito eradication]. PMID- 4211494 TI - [LH-RH axons of the median eminence. Demonstration by an immunocytochemical technic in the duck]. PMID- 4211496 TI - [Mass incidence of typhoid fever in a dormitory Fuji-City, in Shizuoka Prefecture]. PMID- 4211497 TI - [Measurement of coronary blood flow. 1. External measurement of coronary blood flow using radioisotopes]. PMID- 4211498 TI - [Measurement of coronary blood flow. 2. Methods requiring coronary sinus catheterization]. PMID- 4211499 TI - [Measurement of the rates of myocardial fixation by external scanning]. PMID- 4211500 TI - [Mechanical aspects of coronary circulation]. PMID- 4211501 TI - [Mechanism of action of tannic acid on the availability of vitamin B 12 in the intestine]. PMID- 4211502 TI - [Mechanism of various paroxysmal atrio-ventricular blocks. Supranormal period; paradoxical block: Wedensky's phenomena]. PMID- 4211503 TI - [Metabolic effects of salmon calcitonin in the rat after birth]. PMID- 4211504 TI - [Metabolism of the myocardium in man]. PMID- 4211505 TI - [Metal-plastic jaw implant in repair of major mandibular defect after ameloblastoma resection. Report of a case]. PMID- 4211506 TI - [Method of identification of mycobacteria from test material. II. Culture and animal experiment]. PMID- 4211507 TI - [Methyl mercury poisoning]. PMID- 4211508 TI - [Methyldopa and levodopa]. PMID- 4211509 TI - [Microheterogeneity of hemoglobin in lung cancer]. PMID- 4211510 TI - [Modern diagnosis of function in anorectal diseases in childhood, with particular reference to electromanometry (author's transl)]. PMID- 4211511 TI - [Modifications of the corticosterone concentration of adrenal glands and of plasma in the rat fetus after maternal adrenalectomy]. PMID- 4211512 TI - [Morbidity statistics in various age groups]. PMID- 4211513 TI - [Morphologic changes of pulmonary vessels in silicosis]. PMID- 4211514 TI - [Morphologically and metrically comparative study of the hand skeleton in recent primates. II]. PMID- 4211515 TI - [Morphology and histology of the normal and diseased gingival sulcus]. PMID- 4211516 TI - [Motor activity of the rumino-reticulum. I. Character of movements of different parts and their time relations]. PMID- 4211517 TI - [Motor activity of the rumino-reticulum. 2. Movements of different sections and their significance for regurgitation]. PMID- 4211518 TI - [Motor activity of the rumino-reticulum. 3. Character of movements in different sections and of regurgitation during various activities (ruminating, eating, resting)]. PMID- 4211520 TI - [Mycoplasma causing polyarthritis in mice]. PMID- 4211519 TI - [Mutants for the hexuronate transport system in Escherichia coli K 12: physiological and genetic analysis]. PMID- 4211521 TI - [Nasogastric tube feeding (author's transl)]. PMID- 4211522 TI - [Neocortical and archicortical functional connections in the monkey hippocampus]. PMID- 4211523 TI - [Neodymium-YAG laser as an operating instrument in experimental surgery (author's transl)]. PMID- 4211524 TI - [Neurofibromatosis and renovascular hypertension]. PMID- 4211526 TI - [Neurological reflex as a negative feedback]. PMID- 4211525 TI - [Neurofibromatosis and renovascular hypertension]. PMID- 4211527 TI - [Neurophysiological study of antennal motricity in crayfish Palinurus vulgaris]. PMID- 4211528 TI - [New experimental data on the temperature effects on the sex determination in Chelonian embryos]. PMID- 4211529 TI - [New method to analyse the behavior and the frequency of recessive genes with visible effects in bovine populations]. PMID- 4211530 TI - [New observations relative to the action of testosterone on genital ducts, explanted in vitro, of reptile embryos]. PMID- 4211532 TI - [New therapeutic possiblities in depression: the thyrotropin releasing hormone factor]. PMID- 4211533 TI - [Nursing at the rehabilitation ward]. PMID- 4211531 TI - [New technic for examination of chromosomes by electron microscopy]. PMID- 4211535 TI - [On the rhizosphere microflora of the grape vine (Vitis vinifera ssp. sativa, proles pontica, subproles balcanica. A.M. Negrul) "kadarka". I. Morphological, biochemical, and serological characterization of bacteria (author's transl)]. PMID- 4211534 TI - [Ocular and general abnormalities in classical trisomy]. PMID- 4211536 TI - [On the Schimmelpenning-Feuerstein-Mims-syndrome (Organoid Nevus-Phakomatosis) (author's transl)]. PMID- 4211537 TI - [Ophthalmic use of amikacin (author's transl)]. PMID- 4211538 TI - [Ophthalmic, cutaneous and systemic manifestations of malignant granuloma]. PMID- 4211539 TI - [Oral glucose tolerance after selective proximal vagotomy with pyloroplasty (author's transl)]. PMID- 4211540 TI - [Organ culture of rat anterior pituitary gland. Ultrastructure and histochemistry of the 6 granular cell categories observed]. PMID- 4211542 TI - [Originality of the constitution of wheat germ histones]. PMID- 4211541 TI - [Origin of olfacto-gustatory allesthesia: comparative effects of vegetable oil and intragastric glucose]. PMID- 4211543 TI - [Osteoperiosteoplasty of the external table in traumatic defects of the cranium and frontal bone (author's transl)]. PMID- 4211544 TI - [Our preliminary experience in the field of serum prevention of anti-HDN hemolytic disease of the newborn by means of anti-D immunoglobulins]. PMID- 4211545 TI - [Oxyquinolin phthalylsulfathiazole combined with trimethoprim in acute pediatric shigellosis and chronic carriers]. PMID- 4211546 TI - [Paragonimus induced hepatic damage]. PMID- 4211547 TI - [Parapapillay diverticulum and dilatation of the common bile duct without choledocholithiasis]. PMID- 4211548 TI - [Partial study of a case of heavy mu chain disease]. PMID- 4211549 TI - [Pathogenesis of glomerulonephritis--its relationship with streptococcal infections]. PMID- 4211550 TI - [Peculiar endocytosis in erythroblasts with membranous contacts resembling Langerhans granules, in a new variety of anemia]. PMID- 4211551 TI - [Perforating ossified (trichilemmal) "sebaceous" cyst. Apropos of a case]. PMID- 4211552 TI - [Persistance of relatively high blood carbon monoxide after repeated inhaling of tobacco smoke. Epidemiological survey of 642 male patients]. PMID- 4211553 TI - [Pharmacokinetics of radioactively labeled glisoxepide in the animal]. PMID- 4211554 TI - [Pharmacologic action and toxicity of anthorhododendrin]. PMID- 4211555 TI - [Pharmacologic studies of Radix puerariae. I. Its effect on dog arterial pressure, vascular reactivity, and cerebral and peripheral circulation]. PMID- 4211556 TI - [Pharmacologic study of myocardial blood flow by mass spectrometry. 1. Effects of nitroglycerin]. PMID- 4211557 TI - [Pharmacologic study with glisoxepide and other blood sugar reducing sulfonamide derivatives in metabolically healthy subjects and diabetics]. PMID- 4211558 TI - [Phthalophos and sevin dusts for the control of ticks]. PMID- 4211559 TI - [Physicochemical properties of human IgA. General review]. PMID- 4211560 TI - [Physiopathological action of the oil of a French Colza variety on the rat myocardium. Ultrastructural study]. PMID- 4211561 TI - [Polycarboxylate cements]. PMID- 4211562 TI - [Position effect of the cubitus interruptus gene in Drosophila melanogaster. Autoradiographic and fluorescent analysis of a translocated segment of chromosome IV during the position effect]. PMID- 4211563 TI - [Post-traumatic epilepsy (author's transl)]. PMID- 4211564 TI - [Postoperative bronchopleural complications in the combined treatment of lung cancer]. PMID- 4211565 TI - [Postoperative care in subtotal gastrectomy without gastric decompression, intravenous infusion and fasting]. PMID- 4211566 TI - [Pregnancy diagnosis in the swine using vaginal smears]. PMID- 4211567 TI - [Preliminary study of the action of thyrotropin releasing hormone (TRH) in depressive states]. PMID- 4211568 TI - [Preparation and analysis of the bromo derivative of phthiacol]. PMID- 4211569 TI - [Present position of surgery of ileus of the newborn in the region of the jejunum, ileum and colon (author's transl)]. PMID- 4211570 TI - [Prevention of Rh disease by anti-D plasma. A 2-year study]. PMID- 4211571 TI - [Prevention of Rh isoimmunization. Results of prevention with anti D IgG]. PMID- 4211572 TI - [Primary hyperparathyroidism. II. Pathology (author's transl)]. PMID- 4211573 TI - [Problem of the dose of immunoglobulins in the prevention of hemolytic disease of newborn due to materno-fetal incompatibility of antigen D, in case of massive feto-maternal hemorrhage]. PMID- 4211574 TI - [Proceedings: "Beta-type" of spondylitis ankylopoetica]. PMID- 4211576 TI - [Proceedings: Anemia and thrombopathies]. PMID- 4211575 TI - [Proceedings: "Current androgen status" and reserve capacity of Leydig cells in disorders of the hypothalamo-hypophyseal-testicular axis]. PMID- 4211577 TI - [Proceedings: Ankylosing spondylitis (Ap.a.) and the histocompatibility antigen HL-A 27]. PMID- 4211578 TI - [Proceedings: Changes of serum glycoproteins in arterial vascular diseases]. PMID- 4211579 TI - [Proceedings: Clinical and radiological picture of chondrocalcinosis]. PMID- 4211580 TI - [Proceedings: Clinical problems in acute kidney insufficiency]. PMID- 4211581 TI - [Proceedings: Clinical significance of HB-antibody demonstration]. PMID- 4211583 TI - [Proceedings: Demonstration of antibodies against hepatisi-B-antigen with a new radioimmunologic precedure]. PMID- 4211584 TI - [Proceedings: Determination of retention, adhesion and spreading in patients with chronic renal insufficiency, and influence of hemodialysis on platelet function parameters]. PMID- 4211582 TI - [Proceedings: Colitis ulcerosa--ileocolitis Crohn]. PMID- 4211585 TI - [Proceedings: Dialysis treatment using a low-flow dialysate]. PMID- 4211586 TI - [Proceedings: Diverticulosis and diverticulitis]. PMID- 4211587 TI - [Proceedings: Dynamics of growth hormone secretion in acromegaly and normal anterior pituitary gland function]. PMID- 4211588 TI - [Proceedings: Dynamics of insulin secretion in terminal kidney insufficiency and during chronic-intermittent dialysis treatment]. PMID- 4211589 TI - [Proceedings: Effect of pyridinolcarbamate on the lipid metabolism of normal and atherosclerotic intima in human femoral arteries]. PMID- 4211590 TI - [Proceedings: Encephalo- and neuropathies]. PMID- 4211592 TI - [Proceedings: Genetic aspects of lipid metabolism disorders]. PMID- 4211591 TI - [Proceedings: Fluorescence-serologic demonstration of HAA (AuAg) on peripheral blood cells--follow-up studies in acute hepatitis and in subjects with healthy livers]. PMID- 4211593 TI - [Proceedings: Genetics aspects of diabetes]. PMID- 4211594 TI - [Proceedings: Hemo- and crossdialysis treatment of phalloidine intoxication of awake rats]. PMID- 4211595 TI - [Proceedings: Incorporation of 1-14C-oleic acid in subcellular fractions or normal and atherosclerotic human femoral arteries in vitro]. PMID- 4211596 TI - [Proceedings: Influence of antiphlogistic drugs on phagocytosis and lysosomal enzymes in peripheral granulocytes]. PMID- 4211597 TI - [Proceedings: Irritable colon]. PMID- 4211599 TI - [Proceedings: Microrheologic behavior of the blood in diabetes mellitus]. PMID- 4211598 TI - [Proceedings: Metabolism of testosterone and adndrostenedione in leukocytes]. PMID- 4211600 TI - [Proceedings: Normocalcemic primary hyperparathyroidism]. PMID- 4211602 TI - [Proceedings: Osteopathies and calcium metabolism]. PMID- 4211601 TI - [Proceedings: Ophthalmological findings and complications following kidney transplantation]. PMID- 4211603 TI - [Proceedings: Precancerous conditions of the large intestine]. PMID- 4211604 TI - [Proceedings: Preliminary animal experiments on the usability of pilocarpine and a pilocarpine-alupent combination as therapeutic agents in dropsy]. PMID- 4211605 TI - [Proceedings: Prevention of terminal kidney insufficiency]. PMID- 4211606 TI - [Proceedings: Role of bile acids in the formation and dissolution of cholesterol calculi]. PMID- 4211607 TI - [Proceedings: Role of water and electrolytes in homeostasis]. PMID- 4211608 TI - [Proceedings: Sensitiveness and specificity of the solid-phase radioimmunoassay Austria-125 for the demonstration of Australia antigen (HB-Ag)]. PMID- 4211609 TI - [Proceedings: Significance of hydroxyproline determination in 24-hour urine]. PMID- 4211610 TI - [Proceedings: Stimulation of gluconeogenesis in the isolation perfused rat liver following bilateral nephrectomy]. PMID- 4211611 TI - [Proceedings: The arteriosclerotic aorta: structural changes of elastic tissue associated with cholesterin deposition]. PMID- 4211612 TI - [Proceedings: Trialogue on colonic diseases]. PMID- 4211613 TI - [Proceedings: Water intoxication]. PMID- 4211614 TI - [Progesterone biosynthesis by the human placenta in vitro. Kinetic study of the penetration and metabolism of cholesterol in different experimental models]. PMID- 4211615 TI - [Prognostic value of creatinine in the amniotic fluid during normal pregnancies and in cases of Rh isoimmunization]. PMID- 4211616 TI - [Prognostic value of estrioluria HCG and colpocytology in cases with materno fetal Rh isoimmunization]. PMID- 4211617 TI - [Pronostic value of the study of systolic time intervals in recent myocardial infarction]. PMID- 4211618 TI - [Pulmonary complications in the megavolt therapy of bronchial cancer]. PMID- 4211619 TI - [Radiation effects on the blood picture of guinea pigs]. PMID- 4211621 TI - [Radiorestoration by some yeast RNAs of crown-gall tissues, Scorzonera crown-gall tissues treated by CO60 gamma rays]. PMID- 4211620 TI - [Radioautographic observations on DNA-synthesis in the human placenta under normal and pathologic conditions (author's transl)]. PMID- 4211622 TI - [Reactivity of the volatile exometabolites of some blue-green algae, bacteria, fungi and actinomycetes]. PMID- 4211623 TI - [Red blood cells as effectors of thyroid hormones]. PMID- 4211624 TI - [Relations between lysotype changes and the transfer of resistance factors of S. typhi of Mexican origin]. PMID- 4211625 TI - [Relations of retinal vascular occlusions to blood groups of the ABO and RHo (D) system]. PMID- 4211626 TI - [Relationship between acetonemic vomiting and epilepsy]. PMID- 4211627 TI - [Relationship between ABO and rhesus blood group distribution and the localization of stomach cancer]. PMID- 4211628 TI - [Repercussion on the fertility potency of abnormalities observed in young bull sperm]. PMID- 4211629 TI - [Report on the control of typhoid fever and paratyphoid fever: 1970-1971 incidence rate and results of phage typing of isolated bacteria]. PMID- 4211630 TI - [Research on the conformation of anticholinergic compounds]. PMID- 4211631 TI - [Results of prolonged intal therapy in patients with bronchial asthma (author's transl)]. PMID- 4211632 TI - [Rhesus erythrocyte mosaicism. A rapid technic for the separation of red cell populations, using antiglobulin]. PMID- 4211633 TI - [Ribonucleic acids in human serum]. PMID- 4211634 TI - [Role of hypothalamic nonspecific structures in regulation of the pituitary thyroid system]. PMID- 4211635 TI - [Role of lead in medicine]. PMID- 4211636 TI - [Role of the laboratory in the epidemiology of hospital infections caused by Bacillus pyocyaneus]. PMID- 4211637 TI - [Rungi and mycotoxin]. PMID- 4211638 TI - [Search for the sites of synthesis of malt hormone in Blabera craniifer Burm. embryos (Insect, Dictyoptera)]. PMID- 4211639 TI - [Secretion of corticosteroids in rhesus monkeys during adaptation to new ecologic conditions]. PMID- 4211640 TI - [Selective coronary arteriography. II. Radiologic anatomy of coronary arteries of human heart]. PMID- 4211641 TI - [Sensitivity and resistance of Candida to 5-fluorocytosine, 5-fluorouracil and 5 fluorouridine. Relation to the ecology and serotype of C. albicans]. PMID- 4211642 TI - [Septicemia in acute leukemia (author's transl)]. PMID- 4211643 TI - [Serotypes and antibiotic susceptibility of Pseudomonas aeruginosa isolated from clinical materials]. PMID- 4211644 TI - [Serum gastrin level and gastric juice secretion in chronic hemodialysis patients and their modifications through changes in ionized serum calcium achieved by dialysis or parathyroidectomy]. PMID- 4211645 TI - [Significance of the lower incisor's position in the facial profile]. PMID- 4211646 TI - [Simultaneous recording of transmembrane potential and current using a single intracellular microelectrode]. PMID- 4211647 TI - [Skeletal changes in Cushing's syndrome]. PMID- 4211648 TI - [Soil parasitic microorganisms]. PMID- 4211649 TI - [Some patterns of brain functions (author's transl)]. PMID- 4211650 TI - [Specificity of displacement of thyroxin from the protein bond in the rat adenopituitary by synthetic thyrotrophin releasing hormone (TRH) in vitro (author's transl)]. PMID- 4211651 TI - [Speed of irreversible in vivo degradation of free L-isoleucine. Effect of growth hormone]. PMID- 4211652 TI - [Stationary field irradiation of urinary bladder malignomas with ultrahard x-rays of 43 MV]. PMID- 4211653 TI - [Stimulation by serum of phosphorylation and synthesis of non-histone proteins of chromatin in BHK21-C13 cells. Correlation with cellular RNA synthesis]. PMID- 4211655 TI - [Studies of anti-Haemophilus influenzae antibodies in the blood of patients with chronic bronchitis. II. Complement-fixing and precipitating antibodies]. PMID- 4211654 TI - [Structure and properties of milk proteins (review)]. PMID- 4211656 TI - [Studies on amikacin (BB-K8) in the urological field (author's transl)]. PMID- 4211657 TI - [Studies on flavones of Radix puerariae]. PMID- 4211658 TI - [Studies on metabolism of sodium cyclohexylsulfamate. 1. On urinary excretion of cyclohexylamine in monkey and effect of administration of feces of cyclohexylamine excreting monkey and commercial diet to rabbit, guinea pig and rat (author's transl)]. PMID- 4211659 TI - [Studies on the pregnancy-specific beta 1-glycoprotein (SP1) (author's transl)]. PMID- 4211660 TI - [Studies on Fructus schizandrae. I. Its effect on increased SGPT levels in animals caused by hepatotoxic chemical agents]. PMID- 4211661 TI - [Study of interaction between Listeria and macrophages]. PMID- 4211662 TI - [Study of liver biopsies by "hairy cell leukemia" (author's transl)]. PMID- 4211663 TI - [Study of radioactive 5-fluoropyrimidine incorporation in Candida. Mechanism of resistance to 5-fluorocytosine]. PMID- 4211664 TI - [Study of rapid bacteria examination method: Latex agglutination test for isolation of salmonella in food]. PMID- 4211666 TI - [Study of the binding of some acylated sulfonamides with plasma proteins]. PMID- 4211665 TI - [Study of states of vigilance in adult Papio cynocephalus]. PMID- 4211667 TI - [Study of the chromosomal development of the permanent T3 epithelial culture isolated from the mouse mammary adenocarcinoma]. PMID- 4211668 TI - [Study of the fixation of radio-iodinated streptolysin O on erythrocytes]. PMID- 4211669 TI - [Study of the hinge peptide of a human A2m(2) myeloma protein]. PMID- 4211671 TI - [Study on the specificity of anti poly I-poly C antibodies in several mouse strains]. PMID- 4211672 TI - [Subclavian venipuncture and catheterization by supraclavicular approach]. PMID- 4211670 TI - [Study of the sensitivity of Pseudomonas aeruginosa to antiseptics and antibiotics. 5. Relations between lysotypy and sensitivity or resistance to organo-mercuric compounds]. PMID- 4211673 TI - [Sulfonamide and antibiotic usage in otolaryngology (author's transl)]. PMID- 4211674 TI - [Surgical treatment in adult patients with spinal cord injuries (author's transl)]. PMID- 4211675 TI - [Surgical treatment of carcinoma of uterine cervix. Report of 208 cases]. PMID- 4211676 TI - [Survival of acephalic fragments of dendrocoelum lacteum (Planarians) and involution of their abortive blastoma]. PMID- 4211677 TI - [Survival of adrenalectomized and castrated adult female rats]. PMID- 4211678 TI - [Susceptibility of Neisseria gonorrhoeae and blood penicillin level as related to results of treatment of gonorrhea with penicillin]. PMID- 4211679 TI - [Susceptibility to penicillin of randomly selected strains of Neisseria gonorrhoeae]. PMID- 4211680 TI - [Synchronism between the secretory activity of cerebropleural junction neurons and dedifferenciation activity of this area in Crepidula fornicata Phil in female phase]. PMID- 4211682 TI - [Synthesis of dihydroxy-24,25 cholecalciferol, a polar metabolite of vitamin D3]. PMID- 4211683 TI - [Synthesis of releasing hormones]. PMID- 4211681 TI - [Synergistic action of the combination ampicillin-isoxazolylpenicillin]. PMID- 4211684 TI - [Systematic immunization in pregnancy]. PMID- 4211685 TI - [Tasks and results of serological care in pregnancy]. PMID- 4211686 TI - [Taxonomic position of plasmodia that infect man and monkeys]. PMID- 4211688 TI - [The "informed" patient and indication for appendectomy (author's transl)]. PMID- 4211689 TI - [The activity of laryngeal motoneurons during thermic polypnea]. PMID- 4211687 TI - [Temperature denaturation of Salmonella pullorum ribosomes in the presence of certain antibiotics and other biologically active substances]. PMID- 4211690 TI - [The acute abdomen caused by trauma (author's transl)]. PMID- 4211691 TI - [The alveolar soft part sarcoma of the skeletal musculature (author's transl)]. PMID- 4211692 TI - [The bacteriological studies on antibacterial activities of sulbenicillin against clinically isolated strains (author's transl)]. PMID- 4211694 TI - [The chemical structure of the 2d antiscorbutic factor (C2)]. PMID- 4211693 TI - [The binding of 4-(2'-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5 dicarboxylic acid dimethyl ester (nifedipine) as well as other coronary active substances to serum albumins]. PMID- 4211695 TI - [The diabetic disease (M.D.). Clinical picture and complications]. PMID- 4211696 TI - [The effect of combined neonatal thymectomy and splenectomy on viral leukemogenesis in the mouse]. PMID- 4211698 TI - [The hydraulic skeleton of the heart. A working hypothesis on the mechanism of ventricle unfolding]. PMID- 4211697 TI - [The effect of vasodilators on the intraocular pressure (author's transl)]. PMID- 4211699 TI - [The immunotherapeutic approaches to the management of leukemia and neoplasms]. PMID- 4211700 TI - [The mandibular canal and path of the inferior alveolar nerve. Anatomical study]. PMID- 4211701 TI - [The peripheral afferent pathway in acupuncture analgesia]. PMID- 4211702 TI - [The phonomechanograms in chronic coronary insufficiency]. PMID- 4211703 TI - [The pioneer achievement of German teachers in the history of Japanese medicine (author's transl)]. PMID- 4211704 TI - [The recognition and treatment of benign tumors of the esophagus (author's transl)]. PMID- 4211706 TI - [The treatment of neonatal jaundice by photo-therapy with concomitant determination of bilirubin in the urine (author's transl)]. PMID- 4211705 TI - [The role of conditionally pathogenic microbial flora in causing gastrointestinal diseases in young children. A survey of the literature]. PMID- 4211708 TI - [The Prinzmetal variant of angina pectoris (author's transl)]. PMID- 4211707 TI - [The use of a disposable anesthetic lubricant (Instillagel) in catheterization of the urethra (author's transl)]. PMID- 4211709 TI - [Theory of assistance--lessons in modern counseling. 5. Theory of Carl Rogers]. PMID- 4211710 TI - [Therapeutic effect of a new lysergamine derivative with uterotonic action]. PMID- 4211711 TI - [Therapeutic effect of cephapirin in surgical biliary inflammatory diseases (author's transl)]. PMID- 4211712 TI - [Therapeutic use of bacillary dysentery and related diseases: with special reference to the comparison with kanamycin by a double blind method]. PMID- 4211713 TI - [Thin layer chromatography of various aldehyde fuchsines (author's transl)]. PMID- 4211714 TI - [Thyroid function test (author's transl)]. PMID- 4211715 TI - [Thyroid surgery in childhood (author's transl)]. PMID- 4211716 TI - [Torsion of the testis (author's transl)]. PMID- 4211717 TI - [Transfer of fatty acids and proteins between cytoplasmic membranes and mesosomes of Bacillus subtilis var. niger]. PMID- 4211718 TI - [Transformation of ionization measurements to the absorbed dose in dosimetry of high-energy beams of radiation (author's transl)]. PMID- 4211719 TI - [Transient hepatomegaly with glycogen deposition in transient juvenile diabetes with ketosis]. PMID- 4211720 TI - [Treatment of asthma with Intal (disodium cromoglycate)]. PMID- 4211721 TI - [Treatment of diabetic ketoacidosis. I. Insulin in the treatment of diabetic ketoacidosis]. PMID- 4211723 TI - [True needs of the patient: deep-seated psychological process of the patient and re-evaluation of nursing]. PMID- 4211722 TI - [Treatment of infectious diarrhea with drug resistant enterococcus preparation]. PMID- 4211724 TI - [Twins. 2]. PMID- 4211725 TI - [Ulcer diathesis and blood group distribution (author's transl)]. PMID- 4211726 TI - [Ultrastructural and cytochemical location of glycogen in the cat placenta: presence of glycogen bodies]. PMID- 4211727 TI - [Ultrastructural localization of auto-antigen T on the cells of seminiferous tubes of the guinea pig]. PMID- 4211728 TI - [Unsaponified corn oil extract in periodontal therapy]. PMID- 4211729 TI - [Use of acridin dyes in selective media for the isolation of Listeria monocytogenes. II. Modified stuart medium: a new Listeria-transport-enrichment medium (author's transl)]. PMID- 4211730 TI - [Use of citrate nicametate at high doses in cardiovascular surgery]. PMID- 4211731 TI - [Use of new methods in studies on blood coagulation. I. Gel diffusion tests for quantitative determination of thrombin]. PMID- 4211732 TI - [Usefulness of a solid agarfree egg culture medium for the determination of the susceptibility of Neisseria gonorrhoeae to antibiotics by the plate dilution method]. PMID- 4211733 TI - [Usefulness of a solid agarfree egg culture medium in the diagnosis of chronic gonorrhea]. PMID- 4211734 TI - [Utilization of the mean volume (MCV), mean hemoglobin content (MCH) and mean hemoglobin concentration (MCHC) of erythrocytes for the characterization of red cell populations in the dog]. PMID- 4211735 TI - [Valency of radiotomography in the diagnosis of fractures (author's transl)]. PMID- 4211736 TI - [Validity and limits of utilization in man of contractility indices based on the application of the concept of myocardial mechanics to the isovolumetric phase of ventricular contraction]. PMID- 4211737 TI - [Value of cardiac scintigraphic recordings (myocardial and cavitary) in the acute phase of myocardial infarction]. PMID- 4211738 TI - [Value of intravenous pyelography combined with the urea washing test in the detection of renalovascular hypertensions (350 cases)]. PMID- 4211739 TI - [Variations during the cellular cycle of membrane antigen expression detected by antilymphocyte globulins after human lymphoblastic synchronization]. PMID- 4211740 TI - [Variations of capillary blood flow of testis during prepubescent phasis in the male fox(Vulpes vulpes) in captivity]. PMID- 4211742 TI - [Ventricle-unfolding effect of the coronary arterial perfusion pressure or intramural fluid volume. Animal experiments]. PMID- 4211741 TI - [Various functions of a dual immunity system]. PMID- 4211743 TI - [Waldenstrom's disease, amylosis and marastic endocarditis]. PMID- 4211744 TI - [Zoonoses transmitted by laboratory animals]. PMID- 4211745 TI - [1st ultrastructural analysis of the plasticity of cerebellar circuits in vitro]. PMID- 4211746 TI - [13-15 trisomy in mosaicism]. PMID- 4211747 TI - [6-month clinical evaluation of Class II composite resin restorations]. PMID- 4211748 TI - [80th convention of the German Society for Internal Medicine in Wiesbaden, April 21-25, 1974]. PMID- 4211749 TI - [84 cases of enteritis due to Escherichia coli]. PMID- 4211750 TI - A comparative serological study of Dermatophilus congolensis antigens prepared by different methods. PMID- 4211751 TI - A comparative study of human and monkey (Macaca irus) fibrinogen degradation products. PMID- 4211752 TI - A comparative study of the nasal fossa of four nonhuman primates. PMID- 4211753 TI - A comparison of anticoagulants for the analysis of glucose concentration and for haematological measurements in bovine blood. PMID- 4211754 TI - A cytotoxicity assay of Pseudomonas aeruginosa culture filtrates by a dye-uptake test. PMID- 4211755 TI - A fatal adenovirus infection of broiler chickens: inclusion body hepatitis. PMID- 4211756 TI - A microcalorimetric study on the unfolding of E. coli ribosome. PMID- 4211757 TI - A new R factor from Pseudomonas aeruginosa. PMID- 4211758 TI - A plate-diffusion method for the detection of antistaphylolysin activity in human serum. PMID- 4211759 TI - A polyvalent Pseudomonas vaccine. PMID- 4211760 TI - A quick method for calculation of the vascular mean transit time. PMID- 4211761 TI - A radioimmunoassay for measurement of 3,3',5'-triiodothyronine (reverse T3). AB - A highly specific antiserum to 3,3',5'-triiodothyronine (reverse T(3), rT(3)) was prepared by immunization of rabbits with D,L-rT(3)-human serum albumin conjugate. Of the various thyroid hormone derivatives tested, only 3,3'-diiodothyronine (3,3'-T(2)) cross-reacted significantly (10%) with rT(3)-binding sites on the antiserum, while thyroxine (T(4)) and triiodothyronine (T(3)) cross-reacted by less than 0.1%. The antiserum was used in a simple, sensitive, precise, and reproducible radioimmunoassay (RIA) for measurement of rT(3) in ethanolic extracts of serum. The dose-response curves of inhibition of the binding of [(125)I]rT(3) to antibody obtained by serial dilutions of serum extracts were essentially parallel to the standard assay curve. Recovery of nonradioactive rT(3) added to serum before extraction averaged 93%. Serum rT(3) concentrations were found to be (mean+/-SD) 41+/-10 ng/100 ml in 27 normal subjects, 103+/-49 ng/100 ml in 22 hyperthyroid patients, 19+/-9 ng/100 ml in 12 hypothyroid patients, and 54+/-7 ng/100 ml in five subjects with elevated serum thyroxine binding globulin: the values in each of the latter three groups of individuals were significantly different from normal. Reverse T(3) was detected regularly in normal or supranormal concentrations in serum of 12 hypothyroid patients rendered euthyroid or mildly hyperthyroid by treatment with synthetic T(4). It is suggested that serum rT(3) values noted here should be taken to reflect the relative changes in serum rT(3) rather than its absolute values in health and thyroid disease. True serum rT(3) may be somewhat different because: (a) D.L rT(3) employed in the standard curve and L-rT(3) present in human serum may react differently with anti-D,L-rT(2). (b) Even though 3,3'-T(2), which cross-reacted 10% in rT(3) RIA, has been considered unlikely to be present in human serum, it may circulate in low levels. (c) Cross-reaction of T(4) in rT(3) RIA of 0.06% although small, could contribute to RIA estimates of rT(2); the effect of T(4) would be particularly important in case of serum of hyperthyroid patients. Thus, serum rT(3) concentration in hyperthyroid patients averaged 89+/-48 mug/100 ml after correction for cross-reaction effects of T(4): this value was about 14% lower than that before correction (see above). Serum rT(3) concentration in cord sera of seven newborns averaged 136+/-19 ng/100 ml; it was clearly elevated and within the range of values seen in hyperthyroid patients. This was the case when the mean T(4) concentration in the newborn cord sera was moderately higher than normal and about one-half that in hyperthyroid patients, whereas serum T(3) was markedly below the normal adult level. A Pronase hydrolysate of thyroglobulin prepared from pooled normal thyroid glands contained 0.042, 3.0, and 0.16 mug/mg protein of rT(3), T(4), and T(3), respectively. The various data suggest that: (a) rT(3) is a normal component of human serum and thyroglobulin: (b) peripheral metabolism of T(4) is an important source of the rT(3) present in serum: (c) peripheral conversion of T(4) to T(3) and rT(3) may not necessarily be a random process. PMID- 4211762 TI - A search for radioresistance in experimental populations of Drosophila with radiation histories. PMID- 4211763 TI - A simple "variable blade" laryngoscope for use in animals. PMID- 4211764 TI - A simple apparatus for the continuous monitoring of 14CO2 production from several small reaction mixtures. PMID- 4211765 TI - A simple method for accurate assessment of the glomerular filtration rate in children. PMID- 4211766 TI - A study of barrels and pyramidal dendritic clusters in the cerebral cortex. PMID- 4211767 TI - A study of Mycobacterium fortuitum (ranae). PMID- 4211768 TI - A variant of factor 8 related antigen. PMID- 4211769 TI - A Clinicopathologic Conference from Veterans Administration Hospital Hines, Illinois: Nephritis-like symptoms progressing to congestive heart failure. PMID- 4211770 TI - Abnormalities of in vitro thyroid function tests in renal disease. PMID- 4211771 TI - Accidental nosematosis in mice with impaired immunological competence. PMID- 4211772 TI - Acetylation of pronase trypsin. PMID- 4211773 TI - Acid denaturation of human carbonic anhydrase B. A fluorimetric kinetic study. PMID- 4211774 TI - Acidic aqueous extraction of hypothalamic luteinizing hormone releasing hormone to study biological effects. PMID- 4211775 TI - Acquired factor-IX inhibitor in a nonhaemophilic patient with autoimmune disease. PMID- 4211776 TI - Action of flavonoids on blood cells: trimodal action of flavonoids elucidates their inconsistent physiologic effects. PMID- 4211777 TI - Action of metabolic inhibitors on competence and genetic transformation in Bacillus subtilis. PMID- 4211778 TI - Activities of neurons in area 3a of the cerebral cortex during voluntary movements in the monkey. PMID- 4211779 TI - Acute brucellosis with unexpected source. PMID- 4211780 TI - Adjuvants and in vitro antibody production. PMID- 4211781 TI - Affinity chromatography purification of rat alpha 1-foetoprotein. PMID- 4211782 TI - Affinity of UDP-glucuronyl-transferase for several substrates and for chloramphenicol. PMID- 4211783 TI - Albumin and coagulation factor 8 (AHF). PMID- 4211784 TI - Albumin and creatinine clearances in renal disease. PMID- 4211785 TI - Allergic reactions to a horse globulin therapy and their prevention by induction of immunological tolerance. PMID- 4211786 TI - Alteration of vascular permeability in rabbits by culture filtrates of Bacillus cereus and related species. AB - Crude culture filtrates of strains of Bacillus cereus, B. thuringiensis, and B. mycoides caused an increase in vascular permeability when injected intradermally into rabbits. The time course of the change in permeability was determined, and could easily be distinguished from a more transient effect induced by purified (from B. cereus) phospholipase C. The properties of the responsible factor were found to be similar to those reported for the guinea pig dermal factor and the ileal loop fluid inducing factor, namely: synthesis by vigorously aerated, logarithmically growing cells; inactivation by heating at 56 C; non dialyzability; precipitation with ammonium sulfate; and antigenic characteristics. Permeability factor was not related to either the phospholipase C or the hemolysin produced by B. cereus. Activity of this B. cereus toxin, as measured in the vascular permeability and ileal loop assays, can easily be quantitated, but the greater simplicity, reliability, and economy of the vascular permeability test make it the method of choice for screening cultures or following toxin purification. PMID- 4211787 TI - Altered metabolism in a Streptococcus lactis C2 mutant deficient in lactic dehydrogenase. PMID- 4211788 TI - Altered proteins with triosephosphate isomerase activity in suppressor-containing strains of Bacillus subtilis. AB - Suppressor mutations in Bacillus subtilis cause the synthesis of a new protein with the enzymatic activity of l-leucine dehydrogenase and two groups of new proteins with the activity of triosephosphate isomerase. The new isoenzymes of triosephosphate isomerase are separable by zone electrophoresis and differ among themselves in elution behavior upon gel permeation chromatography. One group has an apparent average molecular weight of 120,000 to 135,000, which is more than twice that of the wild-type enzyme. Another group appears to be even higher in molecular weight. These data are consistent with the working hypothesis that the new isoenzymes are produced by extension of growing polypeptide chains through one or more chain-terminating triplets, although other mechanisms resulting in alteration of shapes, charges, or associations of the enzymes are not excluded. PMID- 4211789 TI - Aminoacyl transfer ribonucleic acid synthesis in toluene-treated liver cells. PMID- 4211790 TI - Aminoglycoside antibiotics. V. The 4'-deoxybutirosins (Bu-1975C1 and C2), new aminoglycoside antibiotics of bacterial origin. PMID- 4211791 TI - An acquired lateral ventricular diverticulum appearing as a positive brain scan. PMID- 4211792 TI - An acylated mannan in the membrane of Micrococcus lysodeikticus. PMID- 4211793 TI - An aetiological study of fifty-three female patients from a subnormality hospital and of their offspring. PMID- 4211794 TI - An analysis of the efficiency of a Rhesus haemolytic disease prophylaxis programme. PMID- 4211795 TI - An enzymological approach to the lipidoses. PMID- 4211797 TI - An example of rapid prenatal diagnosis of Fabry's disease using microtechniques. PMID- 4211796 TI - An epidemiologic approach to cancer of the large intestine: the significance of disease relationships. PMID- 4211798 TI - An immunological assay for the sigma subunit of RNA polymerase in extracts of vegetative and sporulating Bacillus subtilis. AB - The activity of the sigma subunit of Bacillus subtilis RNA polymerase decreases markedly during the first hours of sporulation [T.G. Linn et al. (1973) Proc. Nat. Acad. Sci. USA 70, 1865-1869]. We have prepared antibody against RNA polymerase holoenzyme to determine the fate of sigma polypeptide during spore formation. This antiserum specifically and independently precipitates sigma and core polymerase from crude extracts of B. subtilis as judged by both sodium dodecyl sulfate and urea gel electrophoresis of the precipitates. We report that crude extracts of sporulating cells lacking sigma activity contain as much sigma polypeptide as extracts of vegetative cells. However, sigma polypeptide in extracts from sporulating cells is apparently only weakly associated with RNA polymerase, as indicated by the failure of sigma to co-purify efficiently with core enzyme during phase partitioning. The loss of sigma activity and the weak binding of sigma to core enzyme occurs normally in a mutant blocked at an intermediate stage of sporulation (SpoII-4Z) and in wild-type bacteria sporulating in 121B medium, Difco sporulation medium, or Sterlini-Mandelstam resuspension medium. In contrast, sigma in two mutants (SpoOa-5NA and SpoOb-6Z) blocked at an early stage of spore formation remains active and tightly associated with RNA polymerase during stationary phase. PMID- 4211799 TI - An improved test for Haemophilus influenzae precipitins in the serum of patients with chronic respiratory disease. AB - The detection of antibacterial precipitins in the serum of patients with chronic lower respiratory infections has been shown to be of great value in the assessment of pathogenicity of the corresponding bacterial species in the sputum. The test used hitherto, however, is time-consuming and cumbersome owing to the need to distinguish, by immunoelectrophoresis, between antibodies specific to the organism in question and those which react with antigens common to various Gram negative species. A method has now been devised for the preparation of an extract of Haemophilus influenzae containing species-specific antigens only. Use of this extract obviates the need for immuno-electrophoresis and improves the sensitivity of the test. PMID- 4211800 TI - An introduction to principles of veterinary clinical pharmacology: the elimination of drugs. 2. Mechanisms of drug elimination. PMID- 4211801 TI - An investigation of the efficacy of three Brucella vaccines in cattle. PMID- 4211802 TI - An overview of primary endocardial fibroelastosis and chronic viral cardiomyopathy. PMID- 4211803 TI - An unusual expression of Ii antigens in erythrocytes of a healthy adult person. PMID- 4211804 TI - Anabolic and catabolic routes of arginine metabolism in B. subtilis producing bacitracin. PMID- 4211805 TI - Anaesthetic molecules. PMID- 4211806 TI - Analysis of albumin in meconium for early detection of cystic fibrosis. A methodological study. PMID- 4211807 TI - Animal bite. PMID- 4211808 TI - Animal models in psychiatry. PMID- 4211809 TI - Antagonists in the 5-phenyl-benzomorphan series. PMID- 4211810 TI - Anti-heart antibodies in chronic cor pulmonale. PMID- 4211811 TI - Antibody responses in cell cultures from draining and non-draining rabbit lymph nodes primed with native or polymerized human albumin. PMID- 4211812 TI - Antibody to bovine choline acetyltransferase and immunofluorescent localisation of the enzyme in neurones. PMID- 4211813 TI - Arylpyrrolidines as narcotic antagonists. PMID- 4211814 TI - Aspects of experimental hepatocarcinogenesis. 3. Iron overload and hepatocarcinogenesis. PMID- 4211815 TI - Assaying narcotic-antagonist drugs for analgesic activity in rhesus monkeys. PMID- 4211817 TI - Association between histocompatibility type and the ability to make anti-Rh antibodies. PMID- 4211818 TI - Atmospheric transport of polychlorobiphenyls to the North Atlantic. PMID- 4211816 TI - Assessment of the agonist and antagonist properties of narcotic analgesic drugs by their actions on the morphine receptor in the guinea pig ileum. PMID- 4211820 TI - Auditory frequency discrimination in vertebrates. PMID- 4211819 TI - Attempts to induce mycetoma in monkeys and mice using Madurella mycetomi. PMID- 4211821 TI - Australia antigen and hepatitis,. PMID- 4211822 TI - Autoimmune pulmonary fibrosis, an experimental model. PMID- 4211823 TI - Autoimmunity in trypanosome infections. I. Tissue autoantibodies in Trypanosoma (Trypanozoon) brucei infections of the rabbit. PMID- 4211824 TI - Autoradiographic examinations in the early period of wound healing. PMID- 4211825 TI - Autosomal recessive cerebro-oculo-facio-skeletal (COFS) syndrome. PMID- 4211826 TI - Axonal transport of phenylethanolamine-N-methyltransferase in toad sciatic nerve. PMID- 4211827 TI - ABO blood groups, Rhesus negativity, and primary biliary cirrhosis. AB - The distribution of blood groups and Rhesus negativity in 91 British patients with primary biliary cirrhosis was compared with a sample of registered blood donors. There were no significant differences from the expected proportions calculated from the control groups. Although the number of cases studied is small the analysis does not confirm previous reports of an excess of A group in the disease. If a genetic basis exists for primary biliary cirrhosis alternative markers must be found. PMID- 4211828 TI - Bacillus subtilis DNA polymerases. PMID- 4211829 TI - Bacterial attack on phenolic ethers. Preliminary studies on systems transporting electrons to the substrate binding components in bacterial O-dealkylases. PMID- 4211830 TI - Bacterial calcium transport: energy-dependent calcium uptake by membrane vesicles from Bacillus megaterium. AB - Membrane vesicles capable of energy-dependent calcium uptake have been prepared from Bacillus megaterium cells in log-phase growth or when undergoing sporulation. The uptake is dependent on the calcium concentration and appears saturable in vesicles from cells in log-phase growth. Both ascorbate and phenazine methosulfate are needed as a source of electrons for the energy dependent increase in calcium uptake. Addition of 8 mM sodium cyanide inhibited the energy-dependent uptake. If this calcium uptake mechanism is a component of the sporulation-specific calcium accumulation process, the latter's functional expression would appear to be inhibited during log-phase growth. PMID- 4211831 TI - Bactericidal action of a 2-hydroxy-3-alkyl-1,4-naphthoquinone: blockade of metabolite permeation across the membrane. PMID- 4211833 TI - Binding of radioactive chinoform to cohn fractions of human serum by equilibrium dialysis. PMID- 4211832 TI - Bile production in fasted and fed primates. AB - Previous experiments have suggested differences in the bile salt independent flow rate between monkeys and dogs, and in the ability of bile salt secretion to influence bile flow. The present study was performed to determine whether the availability of food could have influenced these results. Bile flow and bile salt secretion rates were studied in fasted and fed primates. In the fasting experiments, sodium cholate, sodium taurocholate, and monkey bile were infused into the duodenum; only sodium cholate was infused in the feeding experiments. The results showed that bile flow was linearly related to the bile salt secretion rate in both fasting and feeding animals. Bile salt independent flow is extremely variable during fasting and is increased and stabilized by feeding. These studies indicate that the differences found in previous experiments are probably attributable to variations in experimental design. PMID- 4211835 TI - Biochemical studies on degenerative neurological disorders. I. Acute experimental encephalitis. PMID- 4211834 TI - Bioavailability of indomethacin in man. PMID- 4211836 TI - Biochemistry of drug dependence. PMID- 4211837 TI - Biochemistry of mammalian fertilization. PMID- 4211839 TI - Blood grouping with a miniature Centrifugal Fast Analyzer. PMID- 4211838 TI - Biochemistry of penicillin and cephalosporin fermentations. PMID- 4211840 TI - Blood lymphocytes after radiation therapy of mammary carcinoma. PMID- 4211841 TI - Brain stem unit activity related to horizontal eye movements occurring during visual tracking. PMID- 4211842 TI - Brain to bottle time. PMID- 4211843 TI - Breakdown of pulse-labeled ribonucleic acid and polysomes in Bacillus megaterium: actions of streptolydigin, echinomycin, and triostins. PMID- 4211844 TI - Bridged amino tetralins. PMID- 4211845 TI - Brucellosis of the carpus. Report of a case. PMID- 4211846 TI - Bursal and postbursal cells in chicken. Separation by gradient centrifugation. PMID- 4211847 TI - Carbonic anhydrases from human neonatal erythrocytes. PMID- 4211848 TI - Carcinogenicity of bracken and shikimic acid. PMID- 4211849 TI - Carcinoma of the larynx in two patients with keratoacanthoma. PMID- 4211850 TI - Cardiohemodynamic effect of 5-methyl-7-diethyl-amino-s-triazolo-(1,5a)pyrimidine (trapymin). PMID- 4211851 TI - Cardiovascular and hematological parameters affected by feeding various polychlorinated biphenyls to the single comb white leghorn cockerel. PMID- 4211852 TI - Care-eliciting behavior in man. PMID- 4211853 TI - Carnosinase: its presence in Pseudomonas aeruginosa. PMID- 4211854 TI - Carrier protein of iodochloroxyquinoline in the serum. PMID- 4211855 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1974. PMID- 4211856 TI - Cationic proteins of human granulocytes. II. Separation of the cationic proteins of the granules of leukemic myeloid cells. PMID- 4211857 TI - Cell-mediated cytotoxicity against ectromelia virus-infected target cells. I. Specificity and kinetics. PMID- 4211858 TI - Cellular sites of immunoglobulins. V. An immunological study of the human gall bladder. PMID- 4211859 TI - Cephacetrile, a new cephalosporin, in the treatment of urinary tract infections. PMID- 4211860 TI - Changes in serum alpha-amylase activity in pigs induced by ethionine intoxication. PMID- 4211861 TI - Characteristics of PRD1, a plasmid-dependent broad host range DNA bacteriophage. AB - Several distinctive properties of PRD1, an icosahedral plasmid-dependent phage, are described. The drug-resistance plasmid-dependent host range of PRD1 extends beyond the P incompatibility group and includes gram-negative bacteria containing plasmids of incompatibility groups N and W. PRD1 phage will infect pseudomonads and Enterobacteriaceae containing either a P or W incompatibility group plasmid. PRD1 adsorbs to the cell wall of R(+) bacteria and thus its infectivity indicates cell wall alterations by these drug-resistance plasmid groups. PRD1 nucleic acid is duplex DNA with an estimated molecular weight of 24 x 10(6). The appearance of PRD1 in electron micrographs is suggestive of lipid content in addition to its buoyant density of 1.348 in CsCl and its sensitivity to chloroform. The latent period of PRD1 varies with the R(+) host bacterial strain used for growth of the phage. PMID- 4211862 TI - Characterization of a calcium-binding IgG myeloma protein. PMID- 4211863 TI - Characterization of persistent Modoc viral infections in Syrian hamsters. AB - Adult Syrian hamsters were readily infected by intranasal inoculation with Modoc virus. Viremias were detected 2 to 6 days after infection and peak viremia titers (10(6.2) plaque-forming units/ml of blood) occurred 4 days postinoculation. All infected animals developed neutralizing and hemagglutination-inhibiting antibodies by 7 days, and complement-fixing antibodies by 14 days postinoculation. High titers of antibodies persisted for at least 4 months. Modoc virus was recovered from throat swabs at 7 days postinoculation, but not at 14 days or later. Urine samples were positive for virus throughout a 12-week observation period. Isolation of virus from lungs and kidneys of one and three animals, respectively, at 151 to 221 days after inoculation confirmed chronic infection. Viral isolations were made only when organs were cultivated in vitro and were unsuccessful by tests on 10% homogenates of the organs. Horizontal viral transmission of virus by infected hamsters that were viruric was demonstrated in only 1 of 27 normal hamsters that were cocaged for 4 weeks under crowded conditions. General failure to obtain horizontal viral transmission may relate to rapid inactivation of virus in excreted urine. Vertical viral transmission was not demonstrated from five chronically infected female hamsters to their 34 offspring. However, if primary infection occurred during pregnancy, the progeny were either stillborn or died shortly after birth, and thus appeared to represent transplacental viral transmission. PMID- 4211864 TI - Characterization of several viruses isolated from chickens with inclusion body hepatitis and aplastic anemia. PMID- 4211865 TI - Characterization of the "pregnancy zone protein" in relation to other alpha 2 globulins of pregnancy. PMID- 4211866 TI - Characterization of the active transport of chlorotetracycline in staphylococcus aureus by a fluorescence technique. PMID- 4211867 TI - Characterization of two melanins produced by Phialophora verrucosa. PMID- 4211868 TI - Chimeric Drosophila adults produced by transplantation of nuclei into specific regions of fertilized eggs. PMID- 4211869 TI - Chitinase in goat serum. Preliminary purification and characterization. PMID- 4211870 TI - Chlorhexidine resistance in Proteus mirabilis. AB - A total of 104 clinical isolates of Pr. mirabilis from three hospitals were screened for their sensitivity to chlorhexidine. The minimum inhibitory concentrations of the antiseptic for these strains ranged from 10 to 800 mug/ml. Two strains sensitive to 20 mug of chlorhexidine/ml were adapted to resistance by growth in subinhibitory concentrations of the antiseptic, their MIC values increasing to 200 and 800 mug/ml. These derived strains exhibited slightly reduced sensitivity to cetrimide and benzalkonium chloride. The chlorhexidine resistant clinical isolates also exhibited this partially decreased sensitivity to the quaternary ammonium compounds. Both the chlorhexidine-sensitive and resistant strains were uniformly sensitive to chloroxylenol (Dettol), glutaraldehyde, and 2-phenoxyethanol. PMID- 4211872 TI - Chorismate mutase from Streptomyces. Purification, properties, and subunit structure of the enzyme from Streptomyces aureofaciens Tu 24. PMID- 4211871 TI - Choice among penicillins and cephalosporins. PMID- 4211874 TI - Classical and alternate pathway activation of complement in pemphigus vulgaris lesions. PMID- 4211873 TI - Citrate metabolism in Aerobacter cloacae. AB - Growth of Aerobacter cloacae on citrate either anaerobically or aerobically did not require and was not stimulated by the presence of Na(+) in the medium. Citrate was metabolized anaerobically via the fermentation pathway as evidenced by the (i) presence of oxalacetate decarboxylase, (ii) induction of citrate lyase, and (iii) repression of alpha-ketoglutarate dehydrogenase under anaerobic conditions. Thus, although all the other enzymes of the citric acid cycle were present in anaerobic cells, this pathway was not available for the metabolism of citrate. Citrate was metabolized aerobically via the citric acid cycle, since (i) citrate lyase but not oxalacetate decarboxylase was repressed and (ii) alpha ketoglutarate dehydrogenase was induced under these conditions. The presence of Na(+) in the medium did not lead to a repression of alpha-ketoglutarate dehydrogenase as in the case of Aerobacter aerogenes. The oxalacetate decarboxylase was a soluble, constitutive enzyme, not activated by Na(+) nor inhibited by avidin. It was slightly inhibited by ethylenediaminetetraacetate but was not stimulated by Mg(2+) or Mn(2+). Thus, this enzyme differed markedly in its properties from the same enzyme found in citrate-grown A. aerogenes. PMID- 4211876 TI - Clinical experience with clonazepam (Rivotril) in the treatment of epilepsy in adults. PMID- 4211875 TI - Clinical and immunologic response to bacteria isolated from tracheal secretions following tracheostomy. PMID- 4211877 TI - Cofactor investigation of bovine plasma amine oxidase. NaBH4 reduction of enzyme substrate mixture. PMID- 4211878 TI - Comparative anatomical studies on the mamillary body of mammals. PMID- 4211879 TI - Comparative aspects of mammary tumors. PMID- 4211880 TI - Comparative biochemistry of p-hydroxymethyl-L-phenylalanine: in vivo studies. PMID- 4211881 TI - Comparison of pharmacological responses to nicotine and release of catecholamines from the adrenals in dogs and monkeys. PMID- 4211882 TI - Computer-assisted pediatric hyperalimentation. PMID- 4211883 TI - Concepts of louse-borne typhus control in developing countries: the use of the living attenuated E strain typhus vaccine in epidemic and endemic situations. PMID- 4211884 TI - Concomitant decrease of the effects of thyroxin on TRH-induced TSH release, and of the pituitary content of triiodothyronine in animals on propylthiouracil. PMID- 4211885 TI - Cone spectral sensitivity studied with an ERG method. PMID- 4211886 TI - Conference on beta cell function, transplantation, and implantable glucose sensors: a summary. PMID- 4211887 TI - Conformational changes of histones and DNA during the thermal denaturation of nucleoprotein. PMID- 4211889 TI - Continuing dental education using closed circuit television. PMID- 4211888 TI - Conformational studies of the unfolding of E. coli ribosome. PMID- 4211890 TI - Continuous intravenous infusion of small doses of insulin in treatment of diabetic ketoacidosis. AB - Continuous intravenous infusion of small amounts of insulin has been used in the management of a series of patients with diabetic ketoacidosis. In 13 patients with a plasma glucose level on admission of 725 mg/100 ml (+/- 80 S.E. of mean) and an arterial pH of 7.07 +/- 0.05 a mean loading dose of 6.5 +/- 0.82 units of soluble insulin was administered intravenously, and thereafter a sustaining infusion of 6.5 +/- 0.82 U/hr was continued until ketosis was corrected and the plasma glucose fell below 300 mg/100 ml. The total insulin dose needed to achieve this was 39.2 +/- 6.6 units given over a 3 to 10-hour period. Plasma insulin was measured in patients who had not previously received insulin and the mean level at an infusion rate of 4 U/hr was 75.6 +/- 8.0 muU/ml. Plasma glucose fell at a regular rate of 101 +/- 11 mg/100 ml/hr, and ketosis improved in parallel. Plasma potassium was well maintained throughout treatment. This regimen of treatment was clinically effective and simple to follow. PMID- 4211891 TI - Control of gene expression in prokaryotic systems. PMID- 4211892 TI - Conventional and dual competitive binding analyses of thyroxine using the Thyopac 4 kit. AB - A simple method is described for the simultaneous determinations of thyroxine and the effective thyroxine ratio (ETR) using a single kit of Thyopac-4. Thyopac ETR values obtained were 1.00 +/- 0.03 for normal subjects; 1.22 +/- 0.11 for hyperthyroid; 0.87 +/- 0.04 for hypothyroid; and 1.02 +/- 0.05 for pregnant women. Cases with TBG deficiency and the nephrotic syndrome indicated normal values. The value (x) was correlated significantly (gamma = + 0.961) with the free Thyopac index (y), representing a regression equation of y = 71.7x(2) - 88.4x + 24.2. Thyopac ETR was shown to be useful in differentiating normal thyroid states from abnormal, irrespective of changes in T(4)-binding globulin (TBG). Further, the T(4) value obtained simultaneously made it possible to detect changes in the TBG level by noting an inconsistent value for the effective thyroxine ratio. PMID- 4211893 TI - Correlations between pantothenate uptake, phospholipid synthesis and pantothenate binding protein formation in Pseudomonas fluorescens P-2. PMID- 4211894 TI - Correlations between quantitative assay of red cell-bound C3, serologic reactions, and hemolytic anemia. PMID- 4211895 TI - Counting the cost. PMID- 4211896 TI - Cross-linking reactions of lamprey fibrinogen and fibrin. PMID- 4211897 TI - Current status of toxicity investigations. PMID- 4211898 TI - Cystoid degeneration of the macula with hole formation in a baboon. PMID- 4211899 TI - Cytogenetic effects of environmental mutagens in mammalian cells and the extrapolation to man. PMID- 4211900 TI - Cytogenetic investigation of the Rhnull phenotype. PMID- 4211901 TI - D-penicillamine therapy of neonatal hyperbilirubinaemia. PMID- 4211902 TI - Deficiency of a carbonic anhydrase (CAI) isoenzyme in the chinchilla. PMID- 4211903 TI - Defining the clinical problem of massive rectal bleeding. PMID- 4211904 TI - Degeneration of mouse pancreatic acinar cells during fasting. PMID- 4211905 TI - Demonstration by immunodiffusion agar-gel test of Borrelia anserina antigen in the organs of infected chickens. PMID- 4211906 TI - Demonstration of indolaminergic fibres in the media eminence of the duck, rat and monkey. PMID- 4211907 TI - Demonstration of two kinds of thyroglobulin-related proteins bound on microsomes of hog thyroid. PMID- 4211908 TI - Dentition of Brachyteles arachnoides with reference to Alouattine and Atelinine affinities. PMID- 4211909 TI - Denturism--again. PMID- 4211910 TI - Deoxyribonucleic acid polymerase 3 (Escherichia coli K12). PMID- 4211911 TI - Detection of antibodies to Campylobacter fetus (Vibrio fetus) in the preputial secretions of bulls with vibriosis. PMID- 4211912 TI - Detection of Australia-SH antigen in serum. A comparison of the electron microscopical, agar gel double diffusion, and complement fixation tests. PMID- 4211913 TI - Detection of Escherichia coli antigens by a latex agglutination test. AB - A latex particle agglutination technique to detect ethylenediaminetetraacetate solubilized extracts from Escherichia coli and whole E. coli cells is described. The sensitivity of the serological test was found to be 0.5 to 2.5 ng for the solubilized antigens and 1.5 x 10(6) to 5.7 x 10(6) cells per ml for the particulate antigens. The test was 100 to 1,000 times more sensitive than the standard bacterial agglutination test. Furthermore, it detected E. coli antigens during all phases of bacterial growth, whereas the bacterial test detected the antigens only after the mid-log phase. No significant cross-reactivity was observed between latex-anti-E. coli preparations and heterologous bacterial strains used in the experimental procedure. A buffer formula containing fatty acid-free bovine albumin prevented nonspecific aggregation of the latex particles. PMID- 4211914 TI - Detergents. PMID- 4211915 TI - Determination of disodium edetate dihydrate in streptomycin by atomic absorption spectrophotometry. PMID- 4211916 TI - Determination of organ volume by means of ultrasonic B-mode scanning. PMID- 4211917 TI - Determination of thyroid volume by ultrasonic scanning. PMID- 4211918 TI - Detoxication of carboxin. PMID- 4211919 TI - Development and behaviour of a strain of bovine ephemeral fever virus with unusual host range. PMID- 4211920 TI - Development and evaluation of an inhalation aerosol of nitroglycerin. PMID- 4211921 TI - Development of the hypothalamohypophysial unit in the chick. PMID- 4211922 TI - Development of Sarcocystis fusiformis in the small intestine of the dog. PMID- 4211923 TI - Diagnosis of gonorrhoea in women. Role of the rectal sample. PMID- 4211924 TI - Diazepam prevents and aborts lidocaine convulsions in monkeys. PMID- 4211926 TI - Differentiation and characterization of isomeric polychlorinated biphenyls by gas liquid chromatography coupled with electron impact and chemical ionization mass spectrometry. PMID- 4211925 TI - Differences in acute and convalescent-phase antibodies of cats infected with feline picornaviruses. AB - Complement fixation inhibiting and complement-fixing antibodies were demonstrated in sera from cats during the acute and convalescent stages, respectively, of feline picornavirus infections. Complement-fixing antibody activity was present in 19S and 7S globulins, whereas complement fixation inhibiting antibody activity was confined to the 7S globulins. Sera with complement-fixing antibody and sera with complement fixation inhibiting antibody were also shown to have neutralizing and precipitating antibodies. In a study of antibody responses to homotypic and heterotypic strains of feline picornavirus, less serological cross-reactions were observed between strains of feline picornavirus in sera from cats in the acute phase of feline picornavirus infection than in the convalescent phase. The temporal relationship of complement fixation inhibiting and complement-fixing antibody responses of cats after acute viral respiratory infections is contrasted with previously observed antibody response in cats to feline leukemia virus. PMID- 4211927 TI - Diphtheria. PMID- 4211928 TI - Discussion paper: antibiotic-sensitive mutants of Escherichia coli possess altered outer membranes. PMID- 4211929 TI - Diseases of the oral mucosa. PMID- 4211930 TI - Disruption of social behaviour of vervet monkeys (Cercopithecus) by low doses of amphetamines. PMID- 4211931 TI - Disseminated mastocytoma and mastocytemia in a dog. PMID- 4211932 TI - Distribution and concentration of TRH in the rat brain. PMID- 4211933 TI - Distribution of lipase in the digestive system of two teleost fishes. PMID- 4211934 TI - Distribution of pentazocine in blood and brain of the baboon following intravenous injection. AB - 1 In the baboon the blood levels of pentazocine between 1 and 60 min after intravenous injection of 0.5 mg/kg were measured by a gas chromatographic technique. From cerebral arteriovenous differences it was shown that the peak of the brain concentration occurred within 15 min and probably within 10 min of intravenous injection. At the time of peak concentration about 10% of the injected dose was in the brain, while the corresponding value at 60 min was 2%.2 The concentration of pentazocine in the brain was an order of magnitude greater than the concentration in cerebral venous blood both at 5 min and 60 min after injection. No major brain interregional differences were demonstrated. Cerebrospinal fluid from the cisterna magna did not yield values from which the cerebral concentration of pentazocine could be predicted. PMID- 4211935 TI - Dithiothreitol-dependent antilisterial activity of lysates from normal macrophages exposed in vitro to culture fluids from spleen cells of BCG-immunized mice. AB - The effect of culture fluids from mouse lymphocytes on the antilisterial activity of normal macrophages in vitro was determined. Titers of lysates of macrophages incubated with or without culture fluids from lymphocytes from control mice had titers of 10 to 270 with or without a reducing agent, dithiothreitol. Lysates of macrophages after incubation with culture fluids of spleen lymphocytes from BCG immunized mice had antilisterial titers with and without dithiothreitol of 197,000 and 810, respectively. This may indicate a dithiothreitol-dependent antilisterial system inherent in activated macrophages of cell-mediated immunity. Lysates of incubated spleen cells and their culture fluids also had slight antilisterial activity. PMID- 4211936 TI - Dose distributions modified by narrow field scanning method in high-energy electron-beam therapy. PMID- 4211937 TI - Double gel diffusion studies on Pseudomonas aeruginosa O antigens. PMID- 4211938 TI - Duodenal perforation: a complication of neonatal nasojejunal feeding. PMID- 4211939 TI - Dynamic aspects of the interaction between antibodies and complement at the cell surface. PMID- 4211940 TI - Dynamics and control mechanisms in maintenance of regional cerebral blood flow. PMID- 4211941 TI - Dynamics of glomerular ultrafiltration. VI. Studies in the primate. PMID- 4211942 TI - Early protein-calorie malnutrition in slum areas of Bangkok Municipality, 1970 71. PMID- 4211943 TI - Ecdysone levels during metamorphosis of Drosophila melanogaster. PMID- 4211944 TI - Echographic evaluation of abdominal tumor regression during antineoplastic treatment. PMID- 4211945 TI - Editorial: Ischemia and the gastric mucosal barrier: a note of caution. PMID- 4211947 TI - Editorial: Optimism in the control of atherosclerosis. PMID- 4211948 TI - Editorial: Primary care defined; Educational development needed. PMID- 4211949 TI - Editorial: Prostheses for the blind. PMID- 4211946 TI - Editorial: Open system in name only? PMID- 4211950 TI - Editorial: The hypothalamic hypophysiotropic thyrotropin releasing hormone (TRH). PMID- 4211951 TI - Effect of aflatoxin on serum proteins, complement activity, and the antibody response to Brucella abortus in guinea pigs. PMID- 4211952 TI - Effect of boric acid on the catalytic activity of Streptomyces griseus protease 3. PMID- 4211954 TI - Effect of dextranase on plaque formation in Macaca mulata. PMID- 4211953 TI - Effect of chrysene and carbon tetrachloride administration on rat hepatic microsomal monooxygenase and UDPglucuronosyltransferase activity. PMID- 4211955 TI - Effect of dietary energy vs. protein restriction on blood constituents and reproductive performance in swine. PMID- 4211957 TI - Effect of exercise on platelet count, adhesion, and aggregation. PMID- 4211956 TI - Effect of estrogens at high dosage on the human endometrium. PMID- 4211958 TI - Effect of fentanyl on pendular rotation nystagmus in squirrel monkeys. PMID- 4211959 TI - Effect of ischemia on hepatic parenchymal and reticuloendothelial function in the baboon. PMID- 4211963 TI - Effect of spermidine on morphogenesis in Myxococcus fulvus. PMID- 4211961 TI - Effect of pH on potential difference and short circuit current in the isolated human cornea. PMID- 4211962 TI - Effect of pH on the catalytic activity of Streptomyces griseus protease 3. PMID- 4211960 TI - Effect of ouabain on sodium transport across hormone-stimulated toad bladder and skin. PMID- 4211964 TI - Effect of the herbicide N-phosphonomethylglycine on the biosynthesis of aromatic amino acids. PMID- 4211965 TI - Effective treatment of gonorrhoea in London with two oral doses of amoxycillin. PMID- 4211967 TI - Effects of carbaryl on mouse organs of reproduction. PMID- 4211968 TI - Effects of chemically pure chlorobiphenyls on the morphology of rat liver. PMID- 4211966 TI - Effects of anesthetics on cerebral, renal, and splanchnic circulations: recent developments. PMID- 4211969 TI - Effects of diphenylamine on sodium and water transport across the toad skin and bladder. PMID- 4211970 TI - Effects of glucocorticoids on TRH and TSH secretion: dose and time considerations. PMID- 4211971 TI - Effects of high-dose medroxyprogesterone given for endometrial carcinoma on serum proteins. PMID- 4211972 TI - Effects of hypophysectomy of liver donor on net synthesis of specific plasma proteins by the isolated perfused rat liver. Modulation of synthesis of albumin, fibrinogen, alpha 1-acid glycoprotein, alpha 2-(acute phase)-globulin, and haptoglobin by insulin, cortisol, triiodothyronine, and growth hormone. PMID- 4211973 TI - Effects of listerial hemolysin on perfused isolated rat hearts. PMID- 4211974 TI - Effects of stress on the results of glucose tolerance tests performed on vervet monkeys (Cercopithecus pygerythrus F. Cuvier). PMID- 4211975 TI - Effects of CI 744 on skeletal muscle activity in monkeys (Macaca mulatta). PMID- 4211976 TI - Electron microscopic observations of Pseudomonas aeruginosa. PMID- 4211977 TI - Elevated alpha1-Antitrypsin serum levels in lung cancer patients. PMID- 4211978 TI - Embryonic defects in Drosophila eggs after partial u.v. irradiation at different wavelengths. PMID- 4211979 TI - Embryonic pole cells and mycoplasmalike symbionts in Drosophila paulistorum. PMID- 4211980 TI - Embryotoxic and teratogenic effect of actinomycin D in the Syrian hamster. PMID- 4211981 TI - Employing mentally retarded ex-residents in the institution. PMID- 4211982 TI - Endoscopic removal of a knotted feeding tube from an infant. PMID- 4211983 TI - Endosymbionts: factors on egg pattern formation. PMID- 4211984 TI - Enhancement of hepatic microsomal drug oxidation and glucuronidation in rat by 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT). PMID- 4211985 TI - Enhancement of tumour growth by lymphoid cells from mice treated with antilymphocyte globulin. PMID- 4211986 TI - Enterocutaneous fistula. The "new look". PMID- 4211987 TI - Enzymatic characterization of sucrose-gradient microbodies of dark-grown, greening and continuously light-grown Euglena gracilis. PMID- 4211988 TI - Enzyme activity of spermatozoa from the ductus deferens of inbred mice. PMID- 4211989 TI - Epidemiology of large bowel disease: the role of fibre. PMID- 4211990 TI - Estimation of chronic dopamine release from the caudate nucleus of the Macaca mulatta. PMID- 4211991 TI - Estimation of the number and size of ribosomal proteins by two-dimensional gel electrophoresis. PMID- 4211993 TI - Evaluation of effects of cytosine arabinoside on Herpesvirus saimiri replication in owl monkey kidney cells. PMID- 4211992 TI - Evaluation in nonhuman primates: evaluation of the physical dependence capacities of oripavine-thebaine partial agonists in patas monkeys. PMID- 4211994 TI - Evaluation of topical povidone-iodine ointment in experimental burn wound sepsis. PMID- 4211995 TI - Evidence for an unusual immunological response to isopentenyladenosine in rabbits. PMID- 4211997 TI - Experimental alterations of prolactin levels in goat milk and blood plasma. PMID- 4211996 TI - Experience with temporary tube gastrostomy for postoperative gastric decompression. PMID- 4211998 TI - Experimental anesthetization of a dromedary camel. PMID- 4211999 TI - Experimental hepatic porphyria induced by polychlorinated biphenyls. PMID- 4212000 TI - Experimental listeria monocytogenes-lymphadenitis. Pathohistological observations. PMID- 4212001 TI - Experimental malnutrition of neurons and glial cells in vitro. I. First stages of degeneration. PMID- 4212002 TI - Experimental malnutrition of neurons and glial cells in vitro. II. Activation of lysosomes and cell death. PMID- 4212003 TI - Experimental studies on the nucleus cervicalis lateralis (NCL) of Macaca cyclopis (Swinhoe). II. The spinal afferents to the nucleus cervicalis lateralis in the monkey. PMID- 4212004 TI - Experimentally induced aberrations in the pattern of differentiation in the cellular slime mould Dictyostelium discoideum. PMID- 4212005 TI - Extensive binding of concanavalin A to the nuclear membrane. PMID- 4212006 TI - Extracellular space in some isolated tissues. AB - 1. The spaces occupied by isotopically labelled inulin, polyethylene glycol, mol. wt. 4000 (PEG 4000), polyethylene glycol, mol. wt. 1000 (PEG 1000) and sucrose in metabolizing mammalian kidney and liver slices and in toad bladder epithelial cell preparations incubated in vitro have been examined.2. In slices of mammalian tissue, and in homogenized liver, it proved impossible to extract inulin completely from tissue which had been dried. However, inulin was recovered as completely from both dried and undried toad bladder epithelial cells scraped from hemibladders incubated in vitro.3. PEG 4000 occupied a space in all preparations similar to that from which inulin was extracted in dried tissue.4. PEG 1000 and sucrose entered cellular water in mammalian slices, but PEG 1000 occupied a similar space to inulin in toad bladder epithelial cell preparations.6. It is concluded that inulin enters cellular water in mammalian slices from which after drying of the slices it cannot be extracted. It thus rather fortuitously provides a measure of extracellular water under these conditions. In preparations of toad bladder epithelial cells inulin seems to be a satisfactory extracellular marker. PEG 4000, which did not appear to enter cellular water also allows a reasonable estimate of extracellular water. PEG 1000 is a suitable extracellular marker for toad bladder epithelial cell preparations but not for mammalian slices. Sucrose entered cellular water in both slices and toad bladder epithelial cells and is not a satisfactory extracellular marker in these tissues. PMID- 4212007 TI - Extraction and purification of kanamycin inactivation enzyme of escherichia coli K12 ML1629. PMID- 4212008 TI - EM autoradiographic studies on polytene nuclei of Drosophila melanogaster. 3. Localisation of non-replicating chromatin in the chromocentre heterochromatin. PMID- 4212009 TI - Factors affecting the uptake of glibenclamide in microdissected pancreatic islets rich in beta-cells. PMID- 4212010 TI - Failure of thyrotropin releasing hormone to increase 125-I uptake by the thyroid in rana temporaria. PMID- 4212011 TI - Fenfluramine: amphetamine congener that fails to maintain drug-taking behavior in the rhesus monkey. AB - Fenfluramine, over a dose range from 0.003 to 3 milligrams per kilogram of body weight, failed to maintain self-injection behavior in rhesus monkeys that had initiated and maintained responding for cocaine or methohexital. This absence of a positive reinforcing effect could not be attributed to a slow onset of drug effect or to the use of behaviorally inactive doses. Fenfluramine, because of its distinctive properties, may produce fewer problems of human abuse than do amphetamine-type agents. PMID- 4212012 TI - Fibrin degradation products in the serum and cerebrospinal fluid of patients with group A meningococcal meningitis. AB - Forty-one patients suffering from group A meningococcal meningitis in an area within the epidemic meningococcal belt of tropical West Africa were studied. The serum of only two of these patients contained fibrin degradation products (FDPs). The cerebrospinal fluid of 21 of these cases was also examined for FDPs, which were present in 13. Their presence in the cerebrospinal fluid was associated with a poor prognosis. PMID- 4212013 TI - Fibrinogen-fibrin degradation products and factor XIII. PMID- 4212014 TI - Fibrinolysis and factor XIII. PMID- 4212015 TI - Fibrous tumor of infancy--report of a case originating in the oral cavity. PMID- 4212016 TI - Fine structure of the sporozoite of Schellackia occidentalis. PMID- 4212017 TI - First clinical experience on the antiepileptic action of taurine. PMID- 4212018 TI - Focal dermal hypoplasia. PMID- 4212020 TI - Fracture conference: Arthrograms of the ankle. Their role in acute trauma. PMID- 4212019 TI - Folic acid and dilantin antagonism in pregnancy. PMID- 4212021 TI - Further characterization of the antigens of canine prostatic fluid. PMID- 4212022 TI - Further studies on the effect of ambilhar on iron metabolism. PMID- 4212023 TI - Further studies on the isotope modification of the mixed hemadsorption technique. Factors influencing the prozone effect. PMID- 4212024 TI - Further studies on Corynebacterium species capable of producing diphtheria toxin (C. diphtheriae, C. ulcerans, C. ovis). PMID- 4212025 TI - Galapagos iguanas: Amblyrhynchus and Conolophus serum protein relationships. PMID- 4212026 TI - Gas chromatographic assay of iduronic and glucuronic acids as aldonic acid butaneboronates. PMID- 4212027 TI - Gastric acid and plasma gastrin responses to sham feeding in duodenal ulcer patients before and after resection of antrum and duodenal bulb. PMID- 4212028 TI - Gastric acid does drive pancreatic bicarbonate secretion. PMID- 4212029 TI - Genetic and biochemical studies on cell-bound alpha-amylase in Bacillus subtilis Marburg. AB - A small but significant amount of alpha-amylase activity was detected in the cells of Bacillus subtilis Marburg. The cell-associated activity was almost constant regardless of the level of extracellular alpha-amylase activity. The cell-bound amylase activity could be separated into three components, upon Sephadex G-75 chromatography, referred to as components A, B, and C. Component C showed the same properties as the extracellular alpha-amylases so far examined. Component A had a molecular weight greater than 70,000, as judged from the elution position on Sephadex G-75, and became smaller upon treatment with trypsin but was still larger than that of component C. An alpha-amylase mutant that lacked extracellular alpha-amylase completely because of a mutation within the structural gene of the enzyme was found to lose all three cell-bound amylase components simultaneously. These data suggest strongly that the cell-bound amylase components are precursors of the extracellular alpha-amylase and that the alpha-amylase of this organism is produced under the direction of the same gene whether the enzyme is within or outside the cell. PMID- 4212030 TI - Genetic control of the rate of alpha-amylase synthesis in Bacillus subtilis. AB - The level of extracellular alpha-amylase (EC 3.2.1.1) of Bacillus subtilis Marburg was increased about fivefold by introducing the amyR marker from B. natto 1212 through transformation. amyR2 of B. natto 1212 has been assumed to determine a high level of alpha-amylase of the organism. The gene acts specifically on alpha-amylase synthesis but not on the production of other extracellular enzymes. alpha-Amylase of an amyR2-carrying strain was found to be quite similar to that of an isogenic amyR1-carrying strain in the thermostability and electrophoretic behavior of whichever amylase the strain produces. Marburg-type alpha-amylase (amyEm) or B. natto-alpha-amylase (amyEn). Anti-amylase serum titration indicates that a high level of the enzyme activity in the amyR2-carrying strain is caused by the existence of more enzyme rather than the presence of an enzyme having higher efficiency. This is supported further by the fact that amyR controls the synthesis of the amyE gene product in mutant M9, which synthesizes a temperature sensitive-alpha-amylase, and in mutant M07, which secretes cross-reacting material. The results indicate that amyR regulates the rate of alpha-amylase synthesis. PMID- 4212031 TI - Genetic mapping in Bacillus subtilis by 5-bromouracil sensitization to ultraviolet inactivation of transforming activities. AB - A new method for chromosome mapping of Bacillus subtilis Marburg is presented which is based on the sensitization to ultraviolet irradiation of transforming deoxyribonucleic acid that has incorporated 5-bromouracil instead of thymine. Deoxyribonucleic acid was extracted at intervals from the outgrowing spores of a thymine-requiring mutant incubated with 5-bromodeoxyuridine and subjected to a definite dose of ultraviolet irradiation. The residual activities of various genetic markers were assayed by transformation. The marker activity of deoxyribonucleic acid that had incorporated 5-bromodeoxyuridine was approximately 10 times as sensitive to ultraviolet irradiation as that of normal deoxyribonucleic acid. The markers proximal to the replication origin were sensitized at earlier times of outgrowth than distal markers. The chromosome replication in outgrowing spores was sufficiently synchronous and allowed the definite determination of when a marker became sensitized by incorporation of 5 bromodeoxyuridine. The time, designated "sensitization time," was estimated by plotting the logarithmic values of relative residual activities versus incubation times. The map constructed with sensitization times as a measurement showed good agreement with those constructed by other methods. The replication of the chromosome under the described conditions appeared to occur in the following marker order: (purA, hisA)-(purB)-(thr, pyrA)-(metC)-(leuA)-(lys, trpC, metB). PMID- 4212033 TI - Genitourinary tuberculosis: review of 102 cases. PMID- 4212032 TI - Genetical load in man. PMID- 4212034 TI - Glucokinase and glucose 6-phosphate dehydrogenase in Neisseria. PMID- 4212035 TI - Gluconeogenesis in ruminants: glucose kinetic parameters in calves under standardized conditions. PMID- 4212036 TI - Glycogen metabolism in glycogen-rich erythrocytes. PMID- 4212037 TI - Glycosyl transferase activity in normal and Scrapie-affected mouse brain. PMID- 4212039 TI - Gonococcal pharyngitis. A report of four cases and a review of the literature. PMID- 4212038 TI - Gonococcal oro- and nasopharyngeal infection. PMID- 4212040 TI - Granulocyte transfusion therapy of experimental Pseudomonas pneumonia. AB - Pseudomonas pneumonia was produced in dogs with radiation-induced leukopenia. Treatment of this infection with either gentamicin alone or gentamicin plus daily granulocyte transfusion was compared in a randomized controlled trail. The dogs receiving granulocytes plus gentamicin survived significantly longer than those treated with gentamicin alone (P < 0.05). The Pseudomonas immunotype which was inoculated into the dogs were recovered at autopsy from none of the granulocyte transfused dogs, whereas seven or eight of the dogs treated with gentamicin alone had the inoculated Pseudomonas immunotype in the area of induced pneumonia at autopsy. As measured by the limulus test, the granulocyte-transfused dogs also did not have endotoxemia as frequently as the dogs given only gentamicin (P < 0.05). This controlled study establishes that transfused granulocytes can favorably alter the course of experimental Pseudomonas pneumonia and suggests that granulocyte transfusion may be a useful therapy in serious bacterial infections of leukopenic subjects. PMID- 4212042 TI - Growth of the Bacillus subtilis cell surface. AB - A double mutant strain, Bacillus subtilis div IV B1 dal trp, has been constructed which grows as filamentous cells and minicells and requires d-alanine for growth. Removal of d-alanine from a growing population of cells resulted in cell bulging 25% of the cell length from one cell pole, followed by cell lysis. Little ultrastructural change in the cell envelope could be detected during bulge formation. PMID- 4212041 TI - Granulomatous reaction in experimental stapedectomy. PMID- 4212043 TI - GLC determination of fluorouracil. PMID- 4212044 TI - GP-350, a sialoglycoprotein from calf brain: its subcellular localization and occurrence in various brain areas. PMID- 4212045 TI - Haemoglobin inkster (alpha2 85aspartic acid leads to valine beta2) coexisting with beta-thalassaemia in a Caucasian family. PMID- 4212046 TI - Haemoglobin Madrid beta 115 (G17) alanine--proline: an unstable variant associated with haemolytic anaemia. PMID- 4212047 TI - Haemolytic disease of new-born due to anti-D antibodies in a Du-positive mother. PMID- 4212048 TI - Haemostatic defects in myelofibrosis. PMID- 4212049 TI - Hematologic malignancies and other marrow failure states: progress in the management of complicating infections. PMID- 4212050 TI - Heterogeneity of monoclonal immunoglobulin-G proteins studied by isoelectric focusing. PMID- 4212051 TI - Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen. PMID- 4212052 TI - Heterotrophic growth of the nitrogen fixing blue-green alga Nostoc muscorum. PMID- 4212053 TI - Histamine content of hypothalamic nuclei of the rat. PMID- 4212054 TI - Histochemical evidence of a hormonal stimulation affecting the postnatal development of murine Paneth cells. PMID- 4212055 TI - Homocystinemia. Vascular injury and arterial thrombosis. PMID- 4212056 TI - Homologies in procaryotic ribosomal proteins: alanine rich acidic proteins associated with polypeptide translocation. PMID- 4212057 TI - Homology of amino-terminal regions of C-phycocyanins from a prokaryote and a eukaryote. PMID- 4212058 TI - Hybridization studies with RNA and DNA isolated from Euglena gracilis chloroplasts and mitochondria. PMID- 4212059 TI - Hydrophobic grid-membrane filters: new approach to microbiological enumeration. AB - A square grid pattern, printed in hydrophobic material on conventional membrane filters, subdivided the surface into a plurality of areas. This separated colonies from one another and prevented lateral growth, spreading, and confluence. Very high colony-packing densities were achieved (2,500/in(2); ca. 1.61 x 10(5)/cm(2)) reducing the need to dilute samples. Recovery of organisms was better than on conventional filters, particularly at high inoculum levels. At the same time, visibility of normally pale or diffuse colonies was improved, since colonies grew upwards instead of sideways, and counting was facilitated because colonies grew in orderly arrays. PMID- 4212060 TI - Hyperalimentation as preparation for surgery in transmural colitis (Crohn's disease). PMID- 4212061 TI - Hypothalamic catecholamines and adrenergic innervation of hypothalamic blood vessels. Potential role in shock. PMID- 4212062 TI - Identification of cone mechanisms in graded responses of foveal striate cortex. AB - 1. The earliest electrical response detectable in foveal striate cortex of anaesthetized Rhesus monkeys following light stimulation is a graded potential which is positive at the cortical surface and negative in the grey matter and has a peak latency of about 60 msec. The response is similar at both the on- and the off-phase of a light stimulus.2. The relationship of this graded potential to the depth of the recording electrode, to the latency of extracellular impulses and to post-synaptic potentials suggests that it is generated by the depolarization of cortical cells.3. Action spectra obtained in the presence of strong selective chromatic adaptation indicate the participation of all three cone mechanisms in this response.4. Each cone mechanism contributes a similar potential to the response but antagonism between cone mechanisms is apparent. The proportion in which a cone mechanism contributes to the response varies from one area to another implying topographical differences in the representation of cone mechanisms in striate cortex. PMID- 4212064 TI - Identification of primate hair. PMID- 4212063 TI - Identification of group B streptococci by immunofluorescence staining. AB - Gamma globulin fractions of rabbit antisera prepared with whole cell vaccines of group B types Ia, Ib, II, and III and labeled with fluorescein isothiocyanate stained group B streptococci type specifically. Type Ic cells, which contain the Ia polysaccharide antigen of type Ia and the Ic protein antigen of type Ib, were specifically stained by both Ia and Ib conjugates. A group B conjugate pool (B pool) that contained one conjugate specific for each group B type at its predetermined titer gave positive fluorescent-antibody (FA) reactions (4+ intensity) with group B stock strains and negative FA reactions (less than 2+ intensity) with stock strains of streptococcal groups A, C through H, and K through U, viridans streptococci, Streptococcus pneumoniae, Staphylococcus aureus, Neisseria gonorrhoeae, and representative Enterobacteriaceae. Examination of 883 clinical isolates submitted to the Streptococcus Laboratory (Center for Disease Control, Atlanta, Ga.) for identification revealed a 99.1% agreement between FA and culture-precipitin methods. All 305 group B streptococci identified by culture-precipitin and six nonhemolytic group B streptococci missed initially by culture tests were identified correctly by FA. Results of cultural and FA methods in a double-blind study of 99 vaginal swabs agreed on 96 of 99 strains. Three nonhemolytic group B streptococci were identified first by FA and later confirmed by culture-precipitin tests. PMID- 4212065 TI - IgG hydrolysis in abscesses. I. A study of the IgG in human abscess fluid. PMID- 4212066 TI - Immune reactions of the syngeneic host after the intradermal injection of tumor cells and microsomes. PMID- 4212067 TI - Immunity and malaria in man. PMID- 4212068 TI - Immunoassay using antibody--enzyme conjugates. PMID- 4212069 TI - Immunodiffusion studies on sera from animals infected with Schistosoma japonicum. PMID- 4212070 TI - Immunofluorescence test for persistent poxvirus antibodies. PMID- 4212071 TI - Immunoglobulin D (IgD) in childhood. II. Serum IgD levels in juvenile rheumatoid arthritis. PMID- 4212072 TI - Immunoglobulins G and M in newborn cord serum. PMID- 4212073 TI - Immunological studies of brain specific protein. PMID- 4212075 TI - Improved method of nasojejunal feeding in low-birth-weight infants. PMID- 4212074 TI - Impaired platelet function in glucose-6-phosphatase deficiency. PMID- 4212076 TI - In vitro hydrolysis of prostaglandin F2alpha, esters by serum or plasma of different animal species. PMID- 4212077 TI - In vitro metabolism of testosterone in seminal vesicles of rats. PMID- 4212078 TI - In vitro restoration of deficient beta-galactosidase activity in liver of patients with Hurler and Hunter disease. PMID- 4212079 TI - In vivo studies on the uptake and binding of beta-lactam antibiotics in relation to inhibition of wall synthesis and cell death. PMID- 4212080 TI - Incidence of antiprotozoal and antivermal antibiotics in fungi. IV. Fungi imperfecti, order Moniliales, collected in China. PMID- 4212081 TI - Increase of fungitoxicity of mercuric chloride by methionine, ethionine and S methylcysteine. PMID- 4212082 TI - Increased diamine oxidase activity in the intestinal lymph of rats on fat ingestion. PMID- 4212083 TI - Increased elevation of peripheral leukocyte counts by infusion of histocompatible granulocytes. PMID- 4212084 TI - Independence of iron absorption from the rate of erythropoiesis. PMID- 4212086 TI - Infantile obesity and later weight control in the baboon. PMID- 4212085 TI - Induction of chronic growth hormone deficiency by anti-GH serum. PMID- 4212087 TI - Influence of acids and salts on the efficiency of the dialyser in the automated analysis of sialic acid. PMID- 4212088 TI - Influence of dietary factors on the gastrointestinal absorption of lead. PMID- 4212090 TI - Inhibition of intestinal absorption of folic acid by phenytoin. PMID- 4212089 TI - Inhibition of antibody formation during continual stimulation with a strong immunogen. PMID- 4212091 TI - Inhibition of the oxytocic action of prostaglandin F2alpha on pregnant rabbit uterus by intra-aortic infusion of theophylline in vivo. PMID- 4212092 TI - Inhibition of Streptomyces griseus protease B by peptide chloromethyl ketones: partial mapping of the binding site and identification of the reactive residue. PMID- 4212093 TI - Initiation of spore germination in Bacillus subtilis: relationship to inhibition of L-alanine metabolism. AB - The inhibitory effects of anthranilic acid esters (methyl anthranilate and N methyl anthranilate) on the l-alanine-induced initiation of spore germination was examined in Bacillus subtilis 168. Methyl anthranilate irreversibly inhibited alanine initiation by a competitive mechanism. In its presence, the inhibition could be reversed only by the combined addition of d-glucose, d-fructose, and K(+). Both l-alanine dehydrogenase and l-glutamate-pyruvate transaminase, enzymes which catalyze the first reaction in l-alanine metabolism, were competitively inhibited by methyl anthranilate. The K(i) values for germination initiation (0.053 mM) and of l-glutamate-pyruvate transaminase (0.068 mM) were similar, whereas that for l-alanine dehydrogenase (0.4 mM) was six to seven times higher. Since a mutant lacking l-alanine dehydrogenase activity germinated normally in l alanine alone, it is speculated that the major pathway of l-alanine metabolism during initiation may be via transmination reaction. PMID- 4212094 TI - Inputs into coronary care during 30 years. A cost effectiveness study. PMID- 4212095 TI - Insensitivity of homocitrate synthase in extracts of Penicillium chyrosogenum to feedback inhibition by lysine. AB - We previously reported that lysine inhibits in vivo homocitrate synthesis in the lysine bradytroph, Penicillium chrysogenum L(1), and that such feedback inhibition could explain the known lysine inhibition of penicillin formation. In the present study, it was found that dialyzed cell-free extracts of mutant L(1) converted [1-(14)C]acetate to homocitrate. This homocitrate synthase activity was extremely labile but could be stabilized by high salt concentrations. The pH optimum of the reaction was 6.9, and the K(m) was 5.5 mM with respect to alpha ketoglutarate. The reaction was also dependent upon the presence of Mg(2+), adenosine 5'-triphosphate, and coenzyme A. Surprisingly, the activity in these crude extracts was not inhibited by lysine. Benzylpenicillin at a high concentration (20 mM) partially inhibited the enzyme, an effect that was enhanced by lysine. Casein hydrolysate also partially inhibited the enzyme. PMID- 4212096 TI - Instrumental detection system based on light scattering for performing assays in which agglutination reactions are used. PMID- 4212097 TI - Insulin is a Drosophila hormone and acts to enhance the differentiation of embryonic Drosophila cells. PMID- 4212098 TI - Insulin-resistant diabetic coma. Acute onset in an unknown diabetic associated with brain-stem infarction and death. PMID- 4212099 TI - Interaction of 125I-thyroxine with rat adenohypophyseal proteins in vitro: effect of temperature. PMID- 4212100 TI - Interactions between exogenous deoxyribonucleic acid and membrane vesicles isolated from Bacillus subtilis 168. AB - Membrane vesicles isolated from competent cultures of Bacillus subtilis 168 bound up to 20 mug of double-stranded deoxyribonucleic acid (DNA) per mg of membrane protein in the presence of ethylenediaminetetraacetate. The formation of the DNA membrane complex was time, temperature, and pH dependent. Eighty per cent of the DNA could be removed from the complex by treatment with deoxyribonuclease I. Nevertheless, the DNA that remained attached to the vesicles appeared to have been attacked by the enzyme, suggesting that all the complexed DNA is located at the outer surface of the vesicles. Pretreatment of DNA with deoxyribonuclease I destroyed its affinity for the vesicles. The extent of binding decreased by the addition of Mg(2+) ions, especially at high DNA concentrations (more than 2 mug/ml). This effect was partially due to membrane-associated Mg(2+)-dependent endonucleolytic activity, which caused double-strand breaks in addition to single strand nicks, and to exonuclease activity. The endonucleolytic activity was enhanced by heating the membranes at 80 C. DNA-membrane association was not markedly affected by sulfhydryl reagents, but was largely inhibited by formaldehyde. Endogenous competence-stimulating activity did not alter the DNA binding capacity of the vesicles. PMID- 4212101 TI - Interactions of narcotic antagonists with receptor sites. PMID- 4212102 TI - Interrelationships of the fibrinolytic, coagulation, kinin generating and complement systems. PMID- 4212103 TI - Intestinal complications of nasojejunal feeding in low-birth-weight infants. PMID- 4212104 TI - Intestinal disaccharidases in primary protein malnutrition in adults. PMID- 4212105 TI - Intestinal effects of 5-hydroxytryptamine and morphine in guinea pigs, dogs, cats and monkeys. PMID- 4212106 TI - Intracellular localization of pyridoxamine-5-phosphate oxidase in rabbit liver. PMID- 4212107 TI - Intragastric self-administration of morphine as a measure of addiction. PMID- 4212108 TI - Investigation of the alpha-galactosidase deficiency in Fabry's disease using antibodies against the purified enzyme. PMID- 4212109 TI - Involvement of mannosyl-phosphoryl-dolichols in mannose transfer to brain glycoproteins. PMID- 4212110 TI - Is singlet oxygen a substrate for superoxide dismutase? No. PMID- 4212111 TI - Is there a venoarterial difference in alpha 1-antitrypsin levels? AB - Serum trypsin inhibitory capacity and alpha(1)-antitrypsin concentrations were compared in venous and arterial bloods obtained simultaneously from patients with chronic airways obstruction. No significant venoarterial difference was observed in most patients, which was contrary to the published findings of Woolcock et al. (1972). PMID- 4212112 TI - Isolation and properties of a staphylococcal protease, preferentially cleaving glutamoyl-peptide bonds. PMID- 4212113 TI - Isolation of a common cell wall antigen from the proteolytic strains of Clostridium botulinum. PMID- 4212114 TI - Isolation of a complex of the subcomponents of the activated first component of complement, Clr--Cls, from ACD-human plasma. PMID- 4212115 TI - Isolation of a fragment, Fh, corresponding to the hinge region of human IgG3. PMID- 4212116 TI - Isolation of mutants defective in alpha-amylase from Bacillus subtilis: genetic analyses. AB - The rate of alpha-amylase (EC 3.2.1.1) synthesis in Bacillus subtilis is regulated by a gene, amyR, located near a structural gene, amyE, for the enzyme. To construct a fine map of the amyR-amyE region, we isolated 28 mutants defective in alpha-amylase activity. Eleven mutants out of 28 showed no alpha-amylase activity, whereas the other 17 showed less alpha-amylase activity than the parent. Out of 17 partially positive alpha-amylase mutants, 10 produced temperature-sensitive enzymes, and 4 produced immunologically altered enzymes, two of which are concurrently temperature-sensitive, and 5 produced smaller amounts of alpha-amylases which are indistinguishable from normal enzyme in their temperature sensitivity and immunological properties. Two out of 11 alpha-amylase negative mutants produced material that cross-reacted with anti-amylase serum, and 3 mutants carried suppressible mutations by the suppressor described by Okubo. Mapping data indicate that all 28 mutation sites are located in the amyE region, and none of the groups of the mutants mentioned above contains lesions that are clustered in a single region of amyE. The amyR gene seems most likely to adjoin the terminal region of amyE. PMID- 4212117 TI - Isotopic labeling and analysis of phosphoproteins from mammalian ribosomes. PMID- 4212118 TI - Kinetic cell-cycle analysis of a cultured mammalian cell population. AB - The parameters of the cell cycle are analyzed in terms of the stochastic theory of cell proliferation for a murine mastocytoma line. The cells were grown in suspension culture under steady-state conditions in a chemostat. Initial estimates of the parameters from synchronous growth indicate that agreement of the data with the model is obtained only if the model is modified to include an initial proliferating fraction of less than 100%, and a cell loss continuing throughout the course of the experiment. The analysis verifies that the modified theory adequately describes the data, and that similar parameters are obtained from both desynchronization and percent labeled mitosis experiments. The average cycle time from 10 desynchronization experiments was 8.24 +/- 0.52 h with a cellular standard deviation of 1.28 +/- 0.18. The combined parameter obtained by dividing the cellular standard deviation by the cycle time is shown to be a useful measure of biological variability well defined over many different experiments. The rate constant for cell loss is about 0.009 which gives an 8% cell loss per cycle. The cell loss is sufficient to account for the apparent deficit in initially proliferating cells. The initial distribution of the synchronous cells is qualitatively examined and is found to be peaked late in G(1) or early in S. PMID- 4212119 TI - Kinetics of complex formation between human carbonic anhydrase B and heterocyclic sulfonamides. PMID- 4212121 TI - Lactoperoxidase coupled to polyacrylamide for radio-iodination of proteins to high specific activity. PMID- 4212120 TI - Lack of effect of gold therapy on abnormal IgG and IgM metabolism in rheumatoid arthritis. PMID- 4212122 TI - Lesions produced by Echis carinatus venom in experimental animals. PMID- 4212123 TI - Letter from the Editor. PMID- 4212124 TI - Letter: A cholinesterase inhibitor produced by Aspergillus terreus. PMID- 4212125 TI - Letter: Bacterial microflora in infants receiving nasojejunal tube feeding. PMID- 4212126 TI - Letter: Colonial morphology of Neisseria gonorrhoeae. PMID- 4212127 TI - Letter: Comments on papers by Reichert and Wong. PMID- 4212128 TI - Letter: Contaminated beta-lactamase and blood cultures. PMID- 4212129 TI - Letter: Ear piercing. PMID- 4212130 TI - Letter: Exercise-induced bronchospasm. PMID- 4212131 TI - Letter: Glutaraldehyde therapy for epidermolysis bullosa. PMID- 4212132 TI - Letter: Gonorrhea. PMID- 4212134 TI - Letter: Parenteral hyperalimentation. PMID- 4212133 TI - Letter: Immobilization of phosphotransferases obtained from resistant bacteria. PMID- 4212136 TI - Letter: Structure of enzymatically acetylated sisomicin by Pseudomonas aeruginosa. PMID- 4212135 TI - Letter: Pheochromocytoma and tricyclic antidepressants. PMID- 4212137 TI - Letter: The use of nabulized Intal in asthma. PMID- 4212138 TI - Letter: Thyroid thermogenesis. PMID- 4212139 TI - Leucocyte glycogen response in inflammatory exudates. PMID- 4212140 TI - Library service tailored to dental needs. PMID- 4212141 TI - Life-threatening Mycoplasma pneumoniae pneumonia. PMID- 4212142 TI - Lipids of potato tubers. IV. Effect of growth and storage on the lipid-degrading enzymes of the potato tuber. PMID- 4212143 TI - Liver iron: changes induced by cooking and acid-peptic digestion. PMID- 4212144 TI - Localization of carbonic anhydrase in avian gastric mucosa, shell gland and bone by immunohistochemistry. PMID- 4212145 TI - Localization of immunoglobulins in urinary bladder tumours. PMID- 4212146 TI - Locomotor behavior of decerebellated arboreal mammals--monkey and raccoon. PMID- 4212147 TI - Long-term care of the hemiplegic patient in the home. PMID- 4212148 TI - Lupus erythematosus syndrome and complete deficiency of the fourth component of complement. PMID- 4212149 TI - Lymphocyte function in breast cancer. PMID- 4212150 TI - Lysogenic conversion to phospholipase A production in Bacillus cereus. PMID- 4212151 TI - Lysozymes in feces from infants and children. PMID- 4212152 TI - Maintenance of the primary symbiote of the pea aphid Acyrthosiphon pisum in liquid media. PMID- 4212153 TI - Malnutrition and deafness. PMID- 4212154 TI - Maternal and lateral transmission of scrapie in sheep. PMID- 4212155 TI - Measurement of intracellular amino acids in cultured skin fibroblasts. The effect of storage on cystine recovery and evaluation of three methods of cell preparation. PMID- 4212156 TI - Mechanism of enzyme action. PMID- 4212157 TI - Mechanisms underlying recovery of eye-head coordination following bilateral labyrinthectomy in monkeys. PMID- 4212158 TI - Membrane-bound transpeptidase and penicillin binding sites in Streptomyces strain R61. PMID- 4212159 TI - Meningococcal vaccine. PMID- 4212160 TI - Messenger ribonucleic acid of dormant spores of Bacillus subtilis. AB - Evidence of the presence of messenger ribonucleic acid (mRNA) in dormant spores of Bacillus subtilis has been obtained. The bulk RNA from spores was isolated and labeled in vitro with tritiated dimethyl sulfate. The spore RNA hybridized to 2.4 to 3.2% of the B. subtilis genome. The RNA hybridized to both the complementary heavy and light fractions of deoxyribonucleic acid (DNA). Bulk RNA from log-phase cells competed with virtually all the spore RNA for the heavy DNA fraction and with part of the spore RNA for the light DNA fraction. Bulk RNA from stage IV cells in sporulation also competed with all of the spore RNA for the heavy DNA fraction and with essentially all the spore RNA for the light DNA fraction. These results indicate that dormant spores contain mRNA species present in both log phase cells and stage IV cells of sporulation. The RNA polymerase in the developing forespore must be able to recognize promotor sites for both log-phase and sporulation genes. PMID- 4212161 TI - Metabolism of ovomucoid by the developing chick embryo. PMID- 4212162 TI - Metabolism of trehalose in Euglena gracilis. Partial purification and some properties of phosphoglucomutase acting on beta-glucose 1-phosphate. PMID- 4212163 TI - Metaplastic ossification of a chronically inflamed anal sac in a dog (a case report). PMID- 4212164 TI - Methodology for the evaluation of pentazocine, prototype of the new morphine agonist-antagonist analgesics. PMID- 4212165 TI - Methods in the study of isoenzymes. PMID- 4212166 TI - Microbial conversion of antibiotics. I. Deacylation of maridomycin by bacteria. PMID- 4212167 TI - Microglioma with paraproteinaemia. AB - A case is reported in which a solitary intracerebral tumour of lymphoreticular cells (microglioma, reticulum cell sarcoma) was associated with the presence of a serum paraprotein. Extensive investigation failed to show any evidence of extracerebral reticulosis. Response of the paraprotein to treatment of the tumour is described. PMID- 4212168 TI - Microsporida of the fall webworn, Hyphantria cunea. I. Identification, distribution, and comparison of Nosema sp. with similar Nosema spp. from other Lepidoptera. PMID- 4212169 TI - Mild familial diabetes with dominant inheritance. PMID- 4212170 TI - Mitigation of experimental inflammatory bowel disease in guinea pigs by selective elimination of the aerobic gram-negative intestinal microflora. PMID- 4212171 TI - Mitotic reduction in rat liver exposed to ultrasound. PMID- 4212172 TI - Modification of hexachlorophene toxicity by dieldrin and aroclor 1254. PMID- 4212173 TI - Modification of some of the toxic effects of daunomycin (NSC-82,151) by pretreatment with the antineoplastic agent ICRF 159 (NSC-129,943). PMID- 4212174 TI - Modification of the response of rats to lethal levels of ozone by enzyme-inducing agents. PMID- 4212175 TI - Modulation of prolactin release by altered levels of thyroid hormones. PMID- 4212176 TI - Molecular studies on glycogen storage diseases. PMID- 4212177 TI - Molecular weight heterogeneity of tropoelastin resulting from proteolysis during preparation. PMID- 4212178 TI - Mothers and therapists evaluate long-term and short-term child therapy. PMID- 4212179 TI - Mucoepidermoid tumors of the intraoral minor salivary glands: a clinicopathologic study of 54 cases. PMID- 4212180 TI - Multiple exposure photography for B-scans. PMID- 4212181 TI - Multiple myeloma and macroglobulinemia. Advances in treatment. PMID- 4212182 TI - Mutants of Bacillus subtilis bacteriophage phi e defective in dTTP-dUTP nucleotidohydrolase. AB - Mutants of bacteriophage phie inducing only 1 to 5% of wild-type levels of dTTP dUTP nucleotidohydrolase give normal bursts of viable progeny phage whose DNA contains 5 to 10% thymine (but no uracil) in place of 5-hydroxymethyluracil. The relative heat lability of one phage mutant enzyme solubilized from the membrane fraction of infected cells suggests that a phie gene codes for the induced dTTPase-dUTPase. PMID- 4212184 TI - Mycobacterium kansasii in Kansas: saprophyte or infection? PMID- 4212183 TI - Mutational analysis of dark endogenous metabolism in the blue-green bacterium Anacystis nidulans. AB - We describe a mutant (strain 704) of the obligate photoautotroph Anacystis nidulans which behaves like the wild type under continuous illumination but which in the dark rapidly loses viability, respires little, and incorporates label into ribonucleic acid and protein at rates considerably less than observed with the darkened wild type. Extracts of this mutant strain show no detectable 6 phosphogluconate dehydrogenase (EC 1.1.1.44) activity. Spontaneous revertants of mutant 704 were selected as survivors of prolonged incubation in darkness. Of 10 such strains examined, none had regained 6-phosphogluconate dehydrogenase activity, and all had lost detectable glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity. Although dark survival of these revertants paralleled that of the wild type, rates of dark endogenous respiration and incorporation of labeled precursors into ribonucleic acid were still very low, comparable to those observed with strain 704. These results are consistent with the following hypotheses concerning dark endogenous metabolism in unicellular blue-green bacteria. (i) Although the oxidative pentose phosphate cycle (hexose monophosphate shunt) may play a major role in endogenous metabolism in A. nidulans, as proposed by others, it is not the only pathway capable of providing energy for maintenance of viability in darkness. (ii) Much of the endogenous metabolic activity (respiration and macromolecular synthesis) observed in darkened cultures of wild-type A. nidulans is not required for survival alone, and must therefore serve other functions. PMID- 4212185 TI - Myocardial and systemic vascular responses to low concentration of carboxyhemoglobin. PMID- 4212186 TI - N-terminal amino acid sequences of Azotobacter vinelandii and Rhodospirillum rubrum flavodoxins. PMID- 4212188 TI - Nasojejunal feeding: a commentary. PMID- 4212187 TI - Narcotic antagonists of the 4-phenylpiperidine series. PMID- 4212189 TI - National health insurance: can the U.S. learn from Canada? PMID- 4212190 TI - Nature of the serum heat-labile accessory factor involved in the metabolic inhibition of Mycoplasma pneumoniae. PMID- 4212191 TI - Necessity for differentiation of rhodochrous group from tubercle bacilli. PMID- 4212192 TI - Neuro-tuberculosis, An unsolved problem. PMID- 4212193 TI - Neurofibroma with aberrant tactile corpuscles. PMID- 4212194 TI - Neuronal correlates of seasonal changes in contrast-detection of prey catching behaviour in toads (Bufo bufo L.). PMID- 4212195 TI - Neurotoxicologic studies of two carbamate pesticides in subacute animal experiments. PMID- 4212196 TI - Neutralization of allotype suppression in rabbits. PMID- 4212198 TI - New preclinical safety evaluation for single-dose clinical pharmacology. PMID- 4212197 TI - New phage-SPO1-induced polypeptides associated with Bacillus subtilis RNA polymerase. AB - RNA polymerase was precipitated from extracts of Bacillus subtilis infected with phage SP01 by antiserum prepared against core RNA polymerase. As shown by sodium dodecyl sulfate gel electrophoresis, the precipitates contained at least five new polypeptides not present in uninfected bacteria, in addition to the known subunits of RNA polymerase. The molecular weights of these polypeptides are (1) 85,000; (II) 40,000; (III) 28,000; (IV) 25,000; and (V) 23,000. Four of the polypeptides (I, III, IV, and V) co-purified with RNA polymerase through gel filtration and phosphocellulose chromatography. A pulse-chase experiment indicated that all five polypeptides are synthesized de novo after infection. The synthesis of polypeptides II, III, and IV commences almost immediately after infection, while polypeptides I and V first appear several minutes later. A sus mutant blocked early in transcription, susF21 [Fujita, et al. (1971) J. Mol. Biol. 57, 301-317] failed to induce polypeptides I, IV, and V, while two other mutants, susF4 and susF14, blocked late in transcription both failed only to induce polypeptide V. PMID- 4212199 TI - Newer antibiotic agents acting on gram-negative organisms. PMID- 4212200 TI - Non-specific genital infection in a general practice. PMID- 4212201 TI - Nongonococcal urethritis. A venereal disease as prevalent as epidemic gonorrhea. PMID- 4212202 TI - Nonneurogenic disorders of the anus and rectum. PMID- 4212203 TI - Normal factor 8 antigen level in combined congenital deficiency of factor V and factor VIII. PMID- 4212204 TI - Normal reproductive performance of mature cockerels fed Aroclor 1248. PMID- 4212205 TI - Nosema connori n. sp., a microsporidian parasite of man. PMID- 4212206 TI - Nuclear segregation in Bacillus subtilis. PMID- 4212207 TI - Observations on the ecology of Schistosoma mattheei Veglia & Le Roux, 1929, in portion of the Kruger National Park and surrounding area using a new quantitative technique for egg output. PMID- 4212208 TI - Observations on the mechanism by which T-lymphocytes exert cytotoxic effects. PMID- 4212209 TI - Occipital lobe epilepsy. A clinical and electroencephalographic study. PMID- 4212210 TI - On the conformation of thyrotropin releasing hormone. PMID- 4212211 TI - One-day oral pivampicillin hydrochloride treatment for acute gonococcal urethritis in male patients. PMID- 4212212 TI - Opiate receptor binding: effects of enzymatic treatments. PMID- 4212213 TI - Opponent-colour cells in different layers of foveal striate cortex. AB - 1. The majority of cells in layer 4B have opponent-colour properties indicating that colour opponency plays an important role in the early stages of visual processing in foveal striate cortex. In contrast to cells in the lateral geniculate nucleus many of these cells receive centre-surround antagonism from the same cone mechanism. Some cells show this spatial antagonism at threshold; others require suprathreshold stimuli for its demonstration.2. The majority of cells in layer 4B do not show orientation or directional selectivity. The proportion of cells with orientation and directional selectivity increases and the proportion of opponent-colour cells decreases with increasing distance above and below layer 4B so that the majority of cells in the outer layers exhibit considerable spatial selectivity without apparent colour opponency. These changing proportions suggest that the latter cells may be receiving their inputs from different types of opponent-colour cells making them sensitive to different types of colour contrast but not to colour per se.3. More opponent-colour cells receive inputs from the red- and green- sensitive cone mechanisms than from the blue-sensitive one. This difference is more marked in layer 4B than 3B suggesting that the latter cortical layer may be more involved in colour vision than the former. PMID- 4212214 TI - Opthalmologic effect of ultrasound at diagnostic intensities. PMID- 4212215 TI - Oral and intravenous toxicity of delta9-tetrahydrocannabinol in rhesus monkeys. PMID- 4212216 TI - Orbital apex syndrome complicating frontal pyocoele. PMID- 4212217 TI - Orbital rhabdomyosarcoma in children. PMID- 4212218 TI - Organic mercury poisoning in children. PMID- 4212220 TI - Os penis. PMID- 4212219 TI - Orthophosphate requirement for the formation of phosphoenolpyruvate from pyruvate by enzyme preparations from photosynthetic bacteria. AB - The formation of phosphoenolpyruvate from pyruvate and adenosine 5'-triphosphate by enzymes from photosynthetic bacteria required inorganic phosphate, thus indicating that these organisms utilize pyruvate, orthophosphate dikinase rather than phosphoenolpyruvate synthase in photosynthesis. PMID- 4212221 TI - Ovarian serous neoplasms in the Rhesus monkey. Electron microscopical observations. PMID- 4212222 TI - Ovulation block by indomethacin, an inhibitor of prostaglandin synthesis: a study of its site of action in rats. PMID- 4212223 TI - Paraquat disposition in rats, guinea pigs and monkeys. PMID- 4212224 TI - Partial purification of proteins isolated from mammalian cornified cells. PMID- 4212225 TI - Partial separation on DEAE-Sephadex of antibodies reactive with plant viruses and their protein subunits. PMID- 4212226 TI - Patient record systems--the making of a precedent? PMID- 4212227 TI - Pellicle-associated structures in the amastigote stage of Trypanosoma cruzi and Leishmania species. PMID- 4212228 TI - Penicillin and other inhibitory substances in quarter milk samples of cows at slaughter. PMID- 4212229 TI - Penicillin and epluchage treatment of hepatic actinomycosis. PMID- 4212232 TI - Peripheral and cardiac factors in experimental septic shock. PMID- 4212231 TI - Penicillium endocarditis of aortic valve prosthesis. PMID- 4212230 TI - Penicillin binding components of bacterial cells and their relationship to the mechanism of penicillin action. PMID- 4212233 TI - Perspectives in nutrition research. PMID- 4212234 TI - Pharmacokinetic evaluation of anticonvulsants prior to efficacy testing exemplified by carbamazepine in epileptic monkey model. PMID- 4212235 TI - Pharmacokinetics of Aroclor 1254 components after intravenous administration to swine and sheep. PMID- 4212236 TI - Pharmacologic effects of MJ 9022-1, a potential tranquilizing agent. PMID- 4212237 TI - Phospholipid metabolism by phagocytic cells. Phospholipases A2 associated with rabbit polymorphonuclear leukocyte granules. AB - Polymorphonuclear leukocytes obtained from sterile peritoneal exudates in rabbits contain two phospholipid-splitting activities (phosphatidylacylhydrolases EC 3.1.1.4), one most active at pH 5.5 and the other between pH 7.2 and 9.0. Hydrolysis of phospholipid was demonstrated using Escherichia coli labeled during growth with [1-(14)C]oleate and then autoclaved to inactivate E. coli phospholipases and to increase the accessibility of the microbial phospholipid substrates. The acid and alkaline phospholipase activities are both membrane bound, calcium dependent, and heat stable, and they appear to be specific for the 2-acyl position of phospholipids. Evidence was also obtained suggesting that the E. coli envelope phospholipids with oleate in position 2 are more readily degraded than those with palmitate. The two activities are associated with azurophilic as well as specific granules (obtained by zonal centrifugation) and with phagosomes (isolated after ingestion of paraffin particles by the granulocytes). Phospholipase A activities at pH 5.5 and pH 7.5 degrade the two major phospholipids of E. coli, phosphatidylethanolamine and phosphatidylglycerol, to the same extent, but the phospholipase activity at acid pH does not hydrolyze micellar dispersions of phosphatidylethanolamine. By contrast, phospholipase A(2) activity at pH 7.5 degrades both types of phosphatidylethanolamine substrates. Heparin and chondroitin sulfate inhibit phospholipase activity at pH 5.5 but have little effect on activity at pH 7.5. All detergents tested inhibited phospholipase activity, and both activities are inhibited by reaction products, free fatty acid and lysophosphatidylethanolamine. This product inhibition is only partially prevented by addition of albumin. Supernatant fractions of granulocyte homogenates contain a heat-labile inhibitor of granule phospholipase activity at pH 7.5. Boiling the fraction not only removes the inhibition but actually results in stimulation of hydrolysis at pH 7.5 as well as pH 5.5. These granule-associated phospholipase A activities of polymorphonuclear leukocytes differ in several of their properties from granule or lysosomal phospholipases of other phagocytic cells. PMID- 4212238 TI - Photo-onycholysis. PMID- 4212239 TI - Photochemistry of bioactive compounds. Photochemical processes of polychlorinated biphenyls. PMID- 4212240 TI - Photoreduction of dyes catalysed by organic and bio-molecules. PMID- 4212241 TI - Physiological effect of protein deficiency with special reference to evaluation of protein nutrition and protein requirement. PMID- 4212243 TI - Pineal structure and function in domestic livestock. PMID- 4212242 TI - Physiological roles of pneumococcal peptidases. AB - A methionyl-specific dipeptidase from Streptococcus pneumoniae has been described. This enzyme and the pneumococcal tripeptidase have been shown to be intracellular, soluble, and constitutive. In addition to their function in cleavage of peptide nutrients, these peptidases may play a role in protein synthesis and turnover. PMID- 4212244 TI - Plasma enzyme activities in Coturnix quail fed graded doses of DDE, polychlorinated biphenyl, malathion and mercuric chloride. PMID- 4212245 TI - Plasma triglycerides in human diabetes. PMID- 4212246 TI - Platelet survival and platelet production in idiopathic thrombocytopenic purpura (ITP). PMID- 4212247 TI - Pleiotropic effects of mutations involved in the regulation of Escherichia coli K 12 alkaline phosphatase. AB - Induction of alkaline phosphatase in wild-type Escherichia coli K-12 leads to the appearance of three new proteins in addition to alkaline phosphatase in the periplasmic space of the bacteria. These proteins are detected in autoradiograms of sodium dodecyl sulfate-acrylamide gel electropherograms of extracts from cells labeled with [(35)S]methionine. Studies with constitutive mutants defective in the three genes phoS, phoT, and phoR that have been shown to regulate alkaline phosphatase synthesis indicate that the three periplasmic proteins are coregulated with alkaline phosphatase. A mutant that has a deletion in the alkaline phosphatase structural gene phoA produces the three proteins, but a newly discovered mutant phoB that has a defect in the expression of alkaline phosphatase fails to produce the three proteins. phoB mutants are shown here to be unable to make detectable amounts of alkaline phosphatase polypeptides, as measured by immunoprecipitins or acrylamide gel electropherograms. On the basis of these results we suggest a new model for the regulation of alkaline phosphatase biosynthesis. In this model, a ternary complex composed of phoB(+) and phoR(+) gene products and an internal metabolite functions as a positive control element to regulate the transcription of several cistrons coding for periplasmic proteins. PMID- 4212248 TI - Pleiotropic effects of suppressor mutations in Bacillus subtilis. AB - Isogenic strains of Bacillus subtilis carrying sup-1 (26), sup-3 (10), or their wild-type alleles were constructed in three genetic backgrounds. The patterns of suppression at 37 and 43.5 C, identity of mapping site, effects of the suppressor genes on growth rate, sporulation, and production of altered enzymes were examined. The similarity of the suppression pattern by sup-1 and sup-3 suggests that the suppressors are of the same type. They do not, however, represent mutations in the same gene, since, based on differences in temperature sensitivity of phage mutants in suppressor-containing hosts, sup-1 and sup-3 insert different amino acids and can coexist within the same cell. The ability to produce slow-migrating forms of enzymes of the type described in the accompanying paper was co-transferred with either of the suppressor genes during transformation, was lost on reversion of the suppressor mutations, and was independent of the genetic background. Similarly, transformation and reversion studies indicate that the additional pleiotropic properties such as slow growth rate and inability to attain competence or to yield plaques with phi105C4, which are characteristic of the Okubo sup-1 strain (HA101B) but not its early sporulation defect, result from the presence of the suppressor mutation. The possible mechanisms by which altered enzyme forms and the additional pleiotropic effects are produced in suppressor strains are discussed. In addition, a newly recognized suppressor phenotype is described and partially characterized. PMID- 4212249 TI - Polyglutamyl derivatives of folate as substrates and inhibitors of thymidylate synthetase. PMID- 4212250 TI - Polyteny and the functional significance of the polytene cell cycle. PMID- 4212251 TI - Pontomedullary listeriosis in renal allograft recipient. PMID- 4212252 TI - Possible role of adenosine deaminase in suboptimal growth of the bacillus anthracis adenine auxotroph mutant. PMID- 4212253 TI - Potent in vitro inhibitors of tyrosinase: metal-binding fractions of tobacco smoke condensate. PMID- 4212254 TI - Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells. PMID- 4212255 TI - Poverty, pregnancy outcome and child development. PMID- 4212257 TI - Practical problems in the organization of a drug trial in two hospital groups. PMID- 4212256 TI - Practical concepts of drug absorption, distribution and loss. AB - Serum concentrations of ampicillin were measured following administration of the drug orally and intravenously to nine normal volunteers. The results were analysed by graphic methods, and the effects of absorption, distribution and loss on the time serum concentration curve are discussed. PMID- 4212258 TI - Preclinical toxicologic evaluation of chromomycin A3 (NSC-58 514) in mice, dogs and monkeys. PMID- 4212260 TI - Prepaid group practice and the delivery of ambulatory care. PMID- 4212259 TI - Preliminary observations on antigen activity of Fasciola gigantica by immunodiffusion test in sheep. PMID- 4212261 TI - Preparation of a soluble, bifunctional enzyme aggregate and studies on its kinetic behaviour in polymer media. PMID- 4212262 TI - Preparation of antisera against different animal serum proteins, using cross reacting specific anti-human sera. PMID- 4212263 TI - Preparation of tRNA's and aminoacyl-tRNA synthetases from Bacillus subtilis cells at various stages of growth and spores. PMID- 4212264 TI - Preparation of vaccines--cell substrates. PMID- 4212265 TI - Presence of amino acid dehydrogenases and transaminases in Myxococcus xanthus during vegetative growth and myxospore formation. AB - The following enzymatic activities were demonstrated in Myxococcus xanthus during growth and myxospore formation: l-alanine dehydrogenase (EC 1.4.1.1), l-glutamic acid dehydrogenase (EC 1.4.1.2), glycine dehydrogenase (EC 1.4.1.5), l-glutamic glyoxylate aminotransferase (EC 2.6.1.4), and l-alanine glyoxylate aminotransferase (EC 2.6.1.12). PMID- 4212266 TI - Pressure-induced dissociation of ribosomes. PMID- 4212267 TI - Prevalence of irregular red cell antibodies and their significance in blood transfusion and antenatal care. PMID- 4212268 TI - Private practice dentists--fight back. 2. PMID- 4212270 TI - Proceedings: Mechanism of insulin release: an approach to the mode of action of sulfonylurea. PMID- 4212269 TI - Problems in cell wall assembly. PMID- 4212271 TI - Proceedings: Psychological tests and drugs. PMID- 4212272 TI - Proceedings: Some aspects of trophism in amphibian slow muscle fibres. PMID- 4212273 TI - Production of hyperimmune serum against collagen and its use for the isolation of specific collagen peptides on immunosorbent columns. PMID- 4212274 TI - Prognostic value of urography in irradiated cervical carcinoma. PMID- 4212275 TI - Propagation and plaquing of Dugbe virus (an ungrouped Nigerian arbovirus) in various mammalian and arthropod cell lines. PMID- 4212276 TI - Propanidid in epilepsy. PMID- 4212277 TI - Properties and inhibition of thymidylate synthetase in Drosophila melanogaster. PMID- 4212278 TI - Prostaglandin F in the peripheral plasma of the rhesus monkey in normal pregnancy and after the administration of dexamethasone and PGF2 alpha. PMID- 4212279 TI - Protection by disodium cromoglycate in airways diseases. PMID- 4212280 TI - Protection of rats from experimental allergic encephalomyelitis with antiserum to guinea-pig spinal cord. PMID- 4212281 TI - Protein synthesis in Bacillus subtilis: differential effect of potassium ions on in vitro peptide chain initiation and elongation. AB - The preparation and fractionation of a highly active and stable in vitro protein synthesizing system from Bacillus subtilis is described. Potassium satisfied the requirement for a monovalent ion when the initiation factor-dependent binding of formyl-methionyl-transfer ribonucleic acid and synthesis of formyl-methionyl puromycin were assayed, whereas it inhibited the reactions for polyphenylalanine synthesis. On the other hand, the ammonium ion satisfied the requirement for all assayed reactions. The in vitro experimental evidence suggested that potassium is an inhibitor of one or a few specific reactions involved in peptide chain elongation in B. subtilis. PMID- 4212282 TI - Proteins in fluid from non-keratinizing jaw cysts. 3. Identification of individual proteins with particular reference to alpha- and beta-globulins, including fibrinogen. PMID- 4212283 TI - Proton magnetic resonance studies of intracellular water in sickle cells. PMID- 4212284 TI - Psychopharmacology of the cannabinoids. A review. PMID- 4212285 TI - Pulmonary edema following generalized convulsions (postictal). PMID- 4212286 TI - Purification and characterization of Streptococcus mutans group d cell wall polysaccharide antigen. AB - The Streptococcus mutans group d antigen of strain B13 has been purified and characterized with respect to chemical composition and immunochemical properties. The antigen was extracted from lyophilized cells or cell walls by using 5% trichloroacetic acid at 5 C for 16 h. The antigen could also be extracted with water or 0.01 N HCl at 100 C for 20 min. The antigen was purified by ion-exchange and gel chromatography and was found to contain 96% carbohydrate, 1.6% protein, and 0.3% phosphorus. Characterization by gas chromatography indicated that the polysaccharide was composed of galactose and glucose in a 2:1 ratio. The antigen contained two serologically active sites: one site specific for group d and a second site common to both group d and group a strains. Agar diffusion and immunoelectrophoresis indicated that the two sites existed on a single molecule. The immunological specificity of the group d polysaccharide site depended on a terminal d-galactose. The purified B13 antigen did not react with antisera specific for the glycerol teichoic acid from streptococci. Anti-d serum rapidly agglutinated whole cells, indicating that the antibody receptor sites of the polysaccharide antigen were at the surface of the streptococcal cell. PMID- 4212288 TI - Purification and properties of an extracellular proteinase of psychrophilic Escherichia freundii. PMID- 4212287 TI - Purification and partial characterization of protease from calf thymus chromatin. PMID- 4212289 TI - Purification and properties of interference factor I: a cistron-specific translation control factor and a subunit of phage RNA replicase. PMID- 4212290 TI - Purification and properties of AMP-aminohydrolase from human placenta. PMID- 4212291 TI - Purification of TF1--a template-specific DNA-binding protein and transcription inhibitor from Bacteriophage SPO1-infected Bacillus subtilis. PMID- 4212292 TI - Pyrroles and related compounds. XXXII. Biosynthesis of protoporphyrin-IX from coproporphyrinogen-3. PMID- 4212293 TI - Pyruvate formate lyase in Rhodospirillum rubrum Ha adapted to anaerobic dark conditions. PMID- 4212295 TI - Quantitative and comparative studies of pharmacological features in the coronary, femoral and renal circulations with different coronary vasodilators. PMID- 4212294 TI - Quantification of the pituitary-thyroid axis in pregnant rats. PMID- 4212296 TI - Radiation sterilization and the anesthetist. PMID- 4212297 TI - Radiation-induced nondisjunction and Robertsonian translocation in Drosophila. PMID- 4212298 TI - Radioimmunoassay of parathyroid hormone: peripheral plasma immunoreactive parathyroid hormone response to ethylenediaminetetraacetate. PMID- 4212299 TI - Rapid screening tests for the diagnosis of bovine brucellosis by the complement fixation test. PMID- 4212300 TI - Rapid transfer of folic acid from blood to bile in man, and its conversion into folate coenzymes and into a pteroylglutamate with little biological activity. PMID- 4212301 TI - Rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase: a comparison and immunological study of purified solubilized preparations, and alteration of enzyme levels by cholestyramine feeding. PMID- 4212302 TI - Rate of incorporation of tritiated thymidine into DNA of normoblastic and megaloblastic bone marrow cells in vitro. PMID- 4212303 TI - Recent trends of isolates from cases of bacteremia in Denmark. PMID- 4212304 TI - Recognition of two distinct groups of human IgM and IgA based on different binding to staphylococci. PMID- 4212305 TI - Reconstitution of spinach ribulose-1,5-diphosphate carboxylase from departed subunits. PMID- 4212306 TI - Recovery from long-term protein-energy deficiency. PMID- 4212307 TI - Red cell and serum proteins of patas monkeys, Cercopithecus (equal Erythrocebus) patas. PMID- 4212308 TI - Red cell life span in sickle cell trait. PMID- 4212309 TI - Regional distribution of homocarnosine and other ninhydrin-positive substances in brains of malnourished monkeys. PMID- 4212310 TI - Regulation of glucosylation of teichoic acid. I. Isolation of phosphoglucomutase in Bacillus subtilis 168. PMID- 4212312 TI - Regulation of rat liver glycogen synthetase D. Role of glucose 6-phosphate and enzyme sulfhydryl groups in activity and glycogen binding. PMID- 4212311 TI - Regulation of glucosylation of teichoic acid. II. Partial characterization of phosphoglucomutase in Bacillus subtilis 168. PMID- 4212313 TI - Regulation of ribosome content in eukaryotes. PMID- 4212314 TI - Reinvestigation of the physicochemical and enzymic properties of L-glutaminase from Pseudomonas. PMID- 4212315 TI - Relationship of oculomotor nuclei to midbrain reticular formation. PMID- 4212316 TI - Relationships between inhibition constants and fractional inhibition in enzyme catalyzed reactions with different numbers of reactants, different reaction mechanisms, and different types and mechanisms of inhibition. PMID- 4212317 TI - Release of mRNP-particles of the informosome type from polyribosomes of higher plant embryos. PMID- 4212318 TI - Removal of organochlorine pesticides and polychlorinated biphenyls from marine oils during refining and hydrogenation for edible use. PMID- 4212319 TI - Resistance to Listeria monocytogenes of guinea pigs sensitized with a simple protein. PMID- 4212320 TI - Responses to acoustic stimuli of units in the auditory cortex of awake squirrel monkeys. PMID- 4212321 TI - Results of combination chemotherapy, surgery, and radiotherapy in children with neuroblastoma. PMID- 4212322 TI - Reversed haemagglutination tests for the detection of hepatitis B antigen. PMID- 4212323 TI - Reversible inactivation by ammonia of assimilatory nitrate reductase in Cyanidium caldarium. PMID- 4212324 TI - Rifampicin in plasma and pleural fluid after single oral doses. PMID- 4212325 TI - Role of metabolic disorders of thyroid hormones in the pathogenesis of diabetes mellitus. PMID- 4212326 TI - Role of packaging in ethylene oxide sterilization. PMID- 4212327 TI - Role of physical and neuroendocrine factors in proximal electrolyte reabsorption. PMID- 4212328 TI - Role of singlet oxygen in some chemiluminescence and enzyme oxidation reactions. PMID- 4212329 TI - Role of some macro and microelements on the nitrogen fixation by the blue-green alga Calothrix sp. PMID- 4212330 TI - Role of the heart in the pathogenesis of endotoxin shock. A review of the clinical findings and observations on animal species. PMID- 4212331 TI - Schizogony of Toxoplasma gondii in tissue cultures. PMID- 4212332 TI - Seasonal variation in serum ascorbic acid and serum lipid composition of free living baboons (Papio ursinus). PMID- 4212333 TI - Selective action of isoniazid on the synthesis of cell wall mycolates in mycobacteria. PMID- 4212334 TI - Selective IgA deficiency in Rh-negative women. PMID- 4212335 TI - Self administration: positive and negative reinforcing properties of morphine antagonists in rhesus monkeys. PMID- 4212336 TI - Serological techniques for the detection of antibodies to porcine thrombocytes. I. The agglutination, fluorescent antibody and immunodiffusion techniques. PMID- 4212338 TI - Simian lymphography. PMID- 4212339 TI - Size of the chromosome of Pseudomonas aeruginosa PAO. AB - Electron microscope examination and velocity sedimentation analysis of the deoxyribonucleic acid released from Pseudomonas aeruginosa spheroplasts indicate that this organism carries the bulk of its genetic determinants in a single duplex deoxyribonucleic acid molecule having a molecular mass of 2.1 x 10(9) daltons. PMID- 4212340 TI - Snake venom toxins. The reactivity of the disulphide bonds of Naja nivea toxin alpha. PMID- 4212342 TI - Sodium cromoglycate: a clinical view. PMID- 4212343 TI - Solubilization and partial purification of alkaline phosphatases of sarcoma 180 TG ascites cells. PMID- 4212344 TI - Some in vitro effects of synthetic thyrotrophin releasing factor on the secretion of thyroid stimulating hormone from the anterior pituitary gland of the domestic fowl. PMID- 4212345 TI - Some properties of the liver-specific delta autoantigen of the rat. PMID- 4212346 TI - Spectrophotometric titration of edetic acid in ophthalmic solutions. PMID- 4212341 TI - Sodium cromoglycate (cromolyn sodium): a review of its mode of action, pharmacology, therapeutic efficacy and use. PMID- 4212347 TI - Spinach leaf phosphoenolpyruvate carboxylase: purification, properties, and kinetic studies. PMID- 4212348 TI - Spinal cord injury clinic: an approach to long-term health maintenance in the individual with spinal cord injury. PMID- 4212349 TI - Stability of certain amino acids in a parenteral nutrition solution. PMID- 4212350 TI - Standardization of the basic concepts in electron microscopic autoradiography. PMID- 4212351 TI - Starvation and the glycogen of the brain and vital organs of the rhesus monkey. PMID- 4212352 TI - Statistical estimate of the total number of operons specific for Bacillus subtilis sporulation. AB - As an alternative to exhaustive mapping, an attempt has been made to obtain a rough estimate of the total number of sporulation operons by statistical treatment. Sixteen sporulation mutants taken at random were characterized biochemically and morphologically. The mutations they contained were mapped to determine whether they fell into any one of 23 known operons. From the proportion that do so (10/16), it is calculated that the most probable number of sporulation operons is 37 (68% confidence limits of 31 and 46). If allowance is made for the fact that two of the operons apparently contain mutagenic "hot spots" and the calculation is amended accordingly, the most probable numbers of operons becomes 42 (limits 33 and 59). PMID- 4212353 TI - Stones in common bile duct: non-operative management. PMID- 4212355 TI - Structure of haemoglobin Wien beta 130 (H8) tyrosine-aspartic acid: an unstable haemoglobin variant. PMID- 4212356 TI - Structure of the oocyst and excystation of sporozoites of Isospora endocallimici n. sp., from the marmoset Callimico goeldii. PMID- 4212354 TI - Structural and immunologic characteristics of subviral components of Sindbis, eastern equine and western equine encephalitis viruses. PMID- 4212357 TI - Structure-activity relationships in narcotic antagonists with N-furylmethyl substituents. PMID- 4212358 TI - Studies of bactericidal activity to Escherichia coli of porcine serum and colostral immunoglobulins and the role of lysozyme with secretory IgA. PMID- 4212359 TI - Studies of folate compounds in nature. Folate compounds in rat kidney and red blood cells. PMID- 4212360 TI - Studies of human kidney antigens. PMID- 4212362 TI - Studies of Pseudomonas aeruginosa infections among hospitalized patients. I. Isolation and identification of nonfermentative gram-negative rods. PMID- 4212361 TI - Studies of prostaglandins and prostaglandin antagonists on bovine pulmonary vein in vitro. PMID- 4212363 TI - Studies on liver aldolases in hereditary fructose intolerance. PMID- 4212364 TI - Studies on slices and isolated cells from fresh osteoarthritic human bone. PMID- 4212365 TI - Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 1. The effect of variations in cultivation conditions and the screening of various enzyme specificities. PMID- 4212366 TI - Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 2. Fractionation on ion-exchange chromatography and gel filtration. PMID- 4212367 TI - Studies on the bacteriolytic activity of Streptomyces albus culture filtrates. 3. Affinity for chitin. PMID- 4212368 TI - Studies on the control of development. In vitro synthesis of HPN and MS nucleotides by ribosomes from either sporulating or vegetative cells of Bacillus subtilis. PMID- 4212369 TI - Studies on the exoerythrocytic stages of simian malaria. IX. Plasmodium simium. PMID- 4212370 TI - Studies on the inhibition of oxotremorine induced tremor by a melanocyte stimulating hormone release-inhibiting factor, thyrotropin releasing hormone and related peptides. PMID- 4212371 TI - Studies on the phosphorylation of nucleolar proteins. Comparison of the phosphorylation patterns of nuclear and nucleolar proteins labeled in vivo and in vitro. PMID- 4212372 TI - Studies on C4 inactivator induced by adenoviruses in KB cell cultures. PMID- 4212373 TI - Study on the in vitro Rieder cell. PMID- 4212374 TI - Subcellular localization and properties of thymidine kinase from adenovirus infected cells. PMID- 4212375 TI - Subtype of affective psychoses classified by response on amineprecursors and monoamine metabolism. PMID- 4212376 TI - Surgical correction of subglottic stenosis of the larynx in infants and children. Progress report. PMID- 4212377 TI - Synaptic alterations in developing cortical infarction: an experimental investigation in monkeys. PMID- 4212378 TI - Synergistic action of increased oxygen tensions and PABA-folic acid antagonists on bacterial growth. PMID- 4212379 TI - Synthesis and resolution of vinylglycine, a beta,gamma-unsaturated alpha-amino acid. PMID- 4212380 TI - Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster. PMID- 4212381 TI - T cell recognition of cell-surface antigens. II. Antigen recognition is necessary yet not sufficient for triggering T cell-mediated immunity. PMID- 4212382 TI - Target calcifications of the spleen in chronic brucellosis (Brucella suis). PMID- 4212383 TI - Temperature-sensitive bobbed mutants in Drosophila melanogaster. PMID- 4212384 TI - Terrestrial adaptations in the hands of Cercopithecinae. PMID- 4212385 TI - The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria. AB - We have investigated whether mammalian cells can repair pyrimidine dimers in their mitochondrial DNA which have been induced by ultraviolet light. The assay system is based upon the ability of the phage T4 UV endonuclease to nick covalently closed circular mitochondrial DNA that contain pyrimidine dimers. Our results show that dimers are not removed from the mitochondrial DNA of mouse L cells or human KB and HeLa cells. There is also no evidence for photoreactivation of mitochondrial DNA. Analyses of ethidium bromide-cesium chloride equilibrium density gradients of mitochondrial DNA isotopically labeled before and after exposure to ultraviolet light show that the total amount of DNA replication is depressed after exposure. In addition, an increase in the frequency of molecules banding at a position expected for intermediate replicating forms and open circular daughter molecules suggests that the rate of replication is slower (or arrested) in molecules with pyrimidine dimers. The absence of a significant amount of mixing of label incorporated before and after ultraviolet-irradiation is evidence against the occurrence of a large amount of genetic exchange between mitochondrial DNA molecules under these conditions. PMID- 4212386 TI - The actions of narcotic antagonists in morphine-dependent rhesus monkeys. PMID- 4212387 TI - The activation of Cls with purified Clr. PMID- 4212388 TI - The anti-Rho(D) responses of immunized volunteers following spaced antigenic stimuli. PMID- 4212389 TI - The antibody response to different measles virus antigens under various conditions of immunization. PMID- 4212390 TI - The application of an indirect method of infecting ticks with piroplasms for use in the isolation of field infections. PMID- 4212391 TI - The barrier function of the gram-negative envelope. PMID- 4212392 TI - The cancer syndrome. PMID- 4212393 TI - The cat eye syndrome. PMID- 4212394 TI - The cerebro-oculo-facio-skeletal syndrome. PMID- 4212396 TI - The circular dichroism of a Drosophila melanogaster satellite DNA. PMID- 4212397 TI - The concentrations of progesterone, estrone and estradiol-17 beta in the peripheral plasma of the rhesus monkey during the final third of gestation, and after the induction of abortion with PGF 2 alpha. PMID- 4212395 TI - The characterization of ribosomal subunits of eukaryotes by ultracentrifugal techniques. Criteria of purity. PMID- 4212398 TI - The decline of cell-mediated immunity in aging mice. PMID- 4212399 TI - The double hemidesmosome: a new intercellular junction (1). PMID- 4212400 TI - The ecology of chigger-borne rickettsiosis (scrub typhus). PMID- 4212401 TI - The effect of ambient temperature on the anti-D assay using the Auto-Analyzer. AB - Using the AutoAnalyzer, the percentage agglutination effected by the anti-D antisera studied showed a varied dependence on the ambient temperature over the manifold subsequent to the incubation period at 37 degrees C. This leads to assays which are a function of the ambient temperature. It is suggested that the entry of a relatively large volume of rouleaux-dispersing agent results in an elution of bound antibody to a new position of equilibrium, the shift being dependent on the particular equilibrium constant of the antibody and the rate of its attainment on the ambient temperature. A constant ambient temperature will lead to greater accuracy of anti-D assay. PMID- 4212402 TI - The effect of different serum concentrations of antimicrobial agents on the Lactobacillus casei folate assay. PMID- 4212403 TI - The effect of dopamine on gastric adrenergic receptors in the goat. PMID- 4212404 TI - The effect of efferent duct ligation on the uptake of 65-ZN by the epididymis and vas deferens of rhesus monkeys (Macaca mulatta). PMID- 4212406 TI - The effect of inferotemporal lesions on memory for visual stimuli in rhesus monkeys. PMID- 4212405 TI - The effect of hydergine on the transit time of cerebral circulation in diffuse cerebral insufficiency. PMID- 4212407 TI - The effect of insulin on the permeability of phosphatidyl choline bimolecular membranes to glucose. PMID- 4212408 TI - The effect of intragastric pH variations on the gastric acid response to sham feeding in duodenal ulcer patients. PMID- 4212409 TI - The effect of minocycline on Candida albicans. AB - Minocycline, a new tetracycline derivative, was found to inhibit the growth of Candida albicans. Inhibition was much affected by the composition of the medium and was difficult to demonstrate in fluid cultures. Study of the rate of budding in shallow broth cultures in Petri dishes showed that the addition of 20 mug/ml minocycline prolonged the lag phase by three hours. C. tropicalis was similarly inhibited and C. guilliermondii and C. parapsilosis to a lesser degree. Six other tetracyclines were tested and found to inhibit Candida only in very high concentrations. PMID- 4212410 TI - The effect of propranolol on left ventricular function in angina pectoris as measured by systolic time intervals. PMID- 4212412 TI - The effect of sulphur dioxide on oxidising enzyme systems in plant tissues. PMID- 4212411 TI - The effect of species-specific vocalization on the discharge of auditory cortical cells in the awake squirrel monkey. (Saimiri sciureus). PMID- 4212413 TI - The effect of synthetic thyrotropin releasing hormone (TRH) on cell proliferation of the anterior pituitary gland in organ culture. Preliminary report. PMID- 4212414 TI - The electrocardiogram of the Japanese (Coturnix coturnix japonica) and Bobwhite (Colinus virginianus) quail. PMID- 4212416 TI - The function of the bladder neck in female goats. PMID- 4212415 TI - The erythrocyte sedimentation rate in Rh-positive and Rh-negative donors. PMID- 4212417 TI - The genes for ribosomal ribonucleic acid. PMID- 4212418 TI - The genetics of Penicillium chrysogenum. PMID- 4212419 TI - The goose that laid the golden bile: gallstone dissolution in man with chenodeoxycholic acid. PMID- 4212421 TI - The hypocalcaemic effect of toluidine blue in sheep. PMID- 4212420 TI - The histochemical demonstration of hydrolytic enzymes in adjuvant-induced arthritis in rats. PMID- 4212422 TI - The influence of pure polychlorinated biphenyl compounds on hepatic function in the rat. PMID- 4212423 TI - The influence of stereochemical factors on drug disposition. PMID- 4212424 TI - The inhibition by somatostatin of the thyrotropin response to thyrotropin releasing hormone in normal subjects. PMID- 4212425 TI - The isolation and partial characterization of sulfonamide-resistant carbonic anhydrases from the liver of the male rat. PMID- 4212426 TI - The isolation of symbiotic streptococci. PMID- 4212427 TI - The kinetics of substrate-competitive inhibition in ternary-complex mechanisms for enzyme reactions involving two substrates. PMID- 4212429 TI - The long term care of the patient suffering from cerebral palsy. 3. PMID- 4212428 TI - The late effects of neonatal hyperthyroidism upon the hypothalamic-pituitary thyroid axis in the rat. PMID- 4212430 TI - The long-term effects of marginal protein-energy deficiency. PMID- 4212431 TI - The measurement of systolic time intervals by echocardiography. PMID- 4212432 TI - The membrane association and dissociation of human glyceraldehyde-3-phosphate dehydrogenase under various conditions of hemolysis. Immunochemical evidence for the lack of binding under cellular conditions. PMID- 4212433 TI - The multi-step cancer therapy concept with time-optimal post-therapy Theoretical aspects. PMID- 4212434 TI - The nature and time of occurrence of radiation-induced nondisjunction of the acrocentric X and fourth chromosomes in Drosophila melanogaster females. PMID- 4212435 TI - The neurological mechanisms of pain. A review. PMID- 4212436 TI - The occurrence in sera with m-components of different proteins related to amyloid fibrils. PMID- 4212438 TI - The president's page: health care delivery. PMID- 4212437 TI - The physiology of mould-yeast dimorphism in the genus Mycotypha (Mucorales). PMID- 4212440 TI - The processing of edge information in visual areas of the cortex as evidenced by evoked potentials. PMID- 4212439 TI - The problem of cultivation of Mycobacterium leprae. A review with criteria for evaluating recent experimental work. AB - Some criteria are presented to help evaluate papers appearing in the literature claiming successful cultivation of M. leprae either in the absence or in the presence of tissue-cultured cells. Recently, electron microscopic studies have definitely shown M. leprae to belong to the genus Mycobacterium and its division to occur through transverse section. A survey is given of the mycobacterial strains isolated in the last 10 years from leprosy lesions. These strains belong to taxonomically different species and cannot be considered to be M. leprae. No substantiated claim was made concerning the in vitro growth of M. leprae and the application of the tissue culture technique has been equally disappointing. The view is expressed that progress towards the in vitro cultivation of M. leprae can be made only as a result of increased knowledge about the intracellular environment and the metabolic activities of this organism, to be obtained by the application of modern biochemical and histochemical techniques. PMID- 4212441 TI - The protection of mice by a specific anti-Erysipelothrix insidiosa-neuraminidase antiserum against Erysipelothrix insidiosa infection. PMID- 4212442 TI - The purification and some properties of brewer's yeast apotransketolase. PMID- 4212443 TI - The purification of the DNA polymerase from Micrococcus luteus. PMID- 4212444 TI - The red crowned mangabey, Cercocebus torquatus, in western Nigeria. PMID- 4212445 TI - The rejection of malignant and non-malignant homografts: a new hypothesis. PMID- 4212446 TI - The relation between nutritional deprivation and immunity. PMID- 4212447 TI - The response of the heterotopic pituitary to thyrotropin releasing hormone (TRH). PMID- 4212448 TI - The risks associated with treatment in the African diabetic. PMID- 4212449 TI - The role of bicarbonate in proximal tubular sodium chloride transport. PMID- 4212450 TI - The role of the mental health practitioner in long-term medical treatment. PMID- 4212452 TI - The solution of the paradox of psychotherapy and its corollaries. PMID- 4212451 TI - The sensitivity of the Rh--anti-Rh system to ordered water of hydration. PMID- 4212453 TI - The specificity of anti-galactocerebroside antibody and its reaction with lysolecithin-solubilized myelin. PMID- 4212454 TI - The synthesis and distribution of DNA in the macronucleus of Euplotes eurystomus. PMID- 4212455 TI - The synthesis of phospholipase C by Bacillus cereus. II. A screening method for mutants. PMID- 4212456 TI - The transplacental passage of thyroxine and foetal thyroid function in the rat. PMID- 4212457 TI - The treatment of unstable ankle fractures. PMID- 4212458 TI - The use of an ultrasonic bath to disrupt cells suspended in volumes of less than 100 micro liters. PMID- 4212459 TI - The use of bovine carotid grafts for hemodialysis and hyperalimentation. PMID- 4212460 TI - The utilization of 2-ketogluconate by Hydrogenomonas eutropha H 16. PMID- 4212461 TI - The vascular lesions of neurofibromatosis. PMID- 4212462 TI - The vitamin A transporting system in porcine plasma. PMID- 4212463 TI - The wheat embryo cell-free system. PMID- 4212465 TI - The Sargenti revival. PMID- 4212464 TI - The Law and force-feeding. PMID- 4212467 TI - Thiosulphate compleximetric determination of bismuth in some organic pharmaceutical chemicals. PMID- 4212466 TI - Theory for the sequence of human and rat enamel dissolution by acid and by EDTA: a correlated scanning and transmission electron microscope study. PMID- 4212468 TI - Thrombocythemia and myocardial ischemia with normal coronary angiogram. PMID- 4212469 TI - Thymectomy and bursectomy in chickens with simultaneous experimental and spontaneous autoimmune disease. PMID- 4212470 TI - Thyrotropin-releasing hormone (TRH): distribution in hypothalamic and extrahypothalamic brain tissues of mammalian and submammalian chordates. PMID- 4212471 TI - Tissue response to cryosurgery of oral cavity in rhesus monkeys. PMID- 4212472 TI - Topology of the caudal fat body of the tumor-w mutant of Drosophila melanogaster. PMID- 4212473 TI - Total cerebral blood flow in the monkey measured by hydrogen clearance. PMID- 4212474 TI - Total intravenous hyperalimentation in the management of cecal fistulas: Report of two cases. PMID- 4212475 TI - Toxicity of aerosol propellants in the respiratory and circulatory systems. IV. Cardiotoxicity in the monkey. PMID- 4212476 TI - Toxicity of halogenated oxyquinolines in dogs. A clinical study. II. History, symptoms, laboratory findings, therapy, and follow-up. PMID- 4212477 TI - Toxicologic studies of four fluorescent whitening agents. PMID- 4212478 TI - Transient diabetes insipidus in a newborn infant. PMID- 4212479 TI - Transmission of parotin through the sacs of everted intestine and its demonstration in mesenteric perfusate. PMID- 4212480 TI - Transmission of Plasmodium fragile to Aotus trivirgatus monkeys. PMID- 4212481 TI - Transpeptidases and D,D-carboxypeptidases in bacilli. PMID- 4212483 TI - Triple tetracycline in lower respiratory tract infections. PMID- 4212484 TI - Trisomy D in bone marrow cells in a patient with chronic myelogenous leukemia. PMID- 4212482 TI - Transplantable immunoglobulin-secreting tumours in rats. IV. Sixty-three IgE secreting immunocytoma tumours. PMID- 4212485 TI - Trisomy 18 mosaicism in two siblings. PMID- 4212486 TI - Triterpenoid carotenoids and related lipids. The triterpenoid carotenes of Streptococcus faecium UNH 564P. AB - 1. The occurrence of a novel series of triterpenoid carotenes in Streptococcus faecium UNH 564P is reported. 2. This series, which comprises the C(30) analogues of phytoene, phytofluene, zeta-carotene, 7,8,11,12-tetrahydrolycopene and neurosporene, appears to be analogous to the C(40) Porter-Lincoln series and a pathway of triterpenoid carotene dehydrogenation is proposed to account for the formation of these compounds. 3. Two cis isomers of the C(30) analogue of neurosporene are described. 4. An appropriate system of nomenclature for these novel compounds is proposed. PMID- 4212487 TI - Triterpenoid carotenoids and related lipids. Triterpenoid monohydroxy- and monoglucosyloxy-carotenoids from Streptococcus faecium UNH 564P. AB - 1. The characterization of two novel triterpenoid xanthophylls occurring in Streptococcus faecium UNH 564P is described. 2. Both are derived formally, and probably biosynthetically, from the C(30) analogue of neurosporene and have been identified as 4-hydroxy-4,4'-diaponeurosporene and its glucoside, 4-d glucopyranosyloxy-4,4'-diaponeurosporene. 3. Problems associated with the use of specific glucosidases in defining the anomerism of carotenoid glucosides are discussed. PMID- 4212489 TI - Tuberculous perforation of the small intestine. PMID- 4212488 TI - Tryptic fragments of Fc from normal human IgG and their interaction with staphylococcal protein A. PMID- 4212490 TI - Two methodological problems. PMID- 4212491 TI - Two methods of extraction and partial purification of Drosophila melanogaster RNA polymerase. PMID- 4212493 TI - Two-dimensional polyacrylamide gel electrophoresis for separation of ribosomal proteins. PMID- 4212492 TI - Two types of molecular evolution. Evidence from studies of interspecific hybridization. AB - To assess the significance of macromolecular sequence differences among species, we compared the serum albumins of 81 pairs of vertebrate species capable of producing viable hybrids. Micro-complement fixation experiments showed that the average difference between the albumins within such pairs was only 3 immunological distance units for placental mammals (31 pairs), but 36 units for frogs (50 pairs). Albumin immunological distance is strongly correlated with other measures of genetic distance, including those made with DNA annealing techniques. It therefore seems likely that mammalian species pairs capable of hybridization are far more similar at the macromolecular sequence level than is the case for most hybridizable frogs. We think the most likely explanation for the marked molecular restriction on hybridization among mammals is that the ratio of regulatory evolution to protein evolution is higher for mammals than for frogs. Mammals may have experienced unusually rapid regulatory evolution; indeed, this could be the factor responsible for their unusually rapid anatomical evolution. PMID- 4212494 TI - Two-step inhibition of Bacillus cereus penicillinase by dicloxacillin. PMID- 4212495 TI - Ultra-structure, in vitro cultivation and metabolism of cells isolated from arthritic human bone. PMID- 4212496 TI - Ultrahistochemical demonstration of calcium ions by a freeze-substitution method. PMID- 4212497 TI - Ultrasonography of the chest wall. PMID- 4212498 TI - Ultrasound and scintigraphy in the differential diagnosis of obstructive jaundice. PMID- 4212499 TI - Ultrastructural study of liver cell injury due to UTP deficiency. PMID- 4212500 TI - Unusual metabolism of caffeine in the squirrel monkey. PMID- 4212501 TI - Uptake and subcellular distribution of vitamin B12 in mouse L1210 leukemic lymphoblasts. PMID- 4212502 TI - Urban rodent-borne disease and rodent distribution in Israel and nighboring countries. PMID- 4212503 TI - Use of central and peripheral temperature measurements in care of the critically ill child. PMID- 4212504 TI - Use of microculture plates and the multiple automated sample harvester for in vitro microassay of bacterial toxins. AB - An in vitro cytotoxicity microassay for the measurement of nanogram quantities of Pseudomonas aeruginosa exotoxin and Vibrio cholerae enterotoxin is described. PMID- 4212505 TI - Use of the single radial diffusion technique for influenza antibody surveys. AB - A survey of antibody to the influenza A/Hong Kong/1/68 (H3N2) and the variant A/England/42/72 (H3N2) was carried out by two methods, haemagglutination inhibition (HI) and single radial diffusion (SRD). A comparison of the sensitivity of the two tests indicated that the proportion of sera that produced a zone of 2.5 mm or larger in the SRD tests was equivalent to the proportion that gave HI titres of 1: 40 or more. The test was carried out on serum samples collected from various regions of England. The results showed that approximately 70% had antibody to the A/HK/1/68 virus and only 35% had antibody to A/England/42/72. The SRD test was shown to have several practical advantages for seroepidemiological studies. PMID- 4212506 TI - Use of trace elements in intravenous hyperalimentation solutions. PMID- 4212507 TI - Use of 8-anilino-1-naphthalenesulfonic acid in radioimmunoassay of triiodothyronine. PMID- 4212508 TI - Uses of prolactin- and growth hormone-producing rat pituitary tumor cells in culture. PMID- 4212509 TI - UDP-glucuronyltransferase activity towards oestriol in fresh and cultured foetal tissues from man and other species. PMID- 4212510 TI - UDP-glucuronyltransferase in perfused rat liver and in microsomes: influence of phenobarbital and 3-methylcholanthrene. PMID- 4212511 TI - Vaccination against Marek's disease: immunizing effect of purified turkey herpes virus and cellular membranes from infected cells. PMID- 4212512 TI - Vertebrobasilar arterial insufficiency with dementia. Controlled trials of treatment with betahistine hydrochloride. PMID- 4212513 TI - Vesicoureteral reflux in the primate. PMID- 4212514 TI - Viral hepatitis and autoimmune liver diseases. PMID- 4212515 TI - Viral vaccines: various cell substrates and long-term prospective studies. PMID- 4212516 TI - Von Willebrand's disease in Italy. A study of 13 families from a small area in the province of Vicenza. PMID- 4212517 TI - 31P-NMR studies of tRNA. PMID- 4212519 TI - [Metabolic complications of the treatment of acute leukemia with L-asparaginase (apropos of 147 cases)]. PMID- 4212518 TI - 5'-Nucleotidase and an acid phosphatase of spinal cord. Comparative histochemistry and specificity of the enzymes in mouse and cat spinal cords. Cytologic localization in mouse substantia gelatinosa. PMID- 4212520 TI - [2 years' use of sodium cromoglycate]. PMID- 4212521 TI - Panel discussion: practical importance of generic equivalence. PMID- 4212522 TI - 'A matter of routine'; relationships between temporary disablement patterns of stress and type of care. PMID- 4212523 TI - "The classification of viruses; why, when, and how". PMID- 4212524 TI - ["Morbus diabeticus". Etiopathogenesis--clinical classification: under the term Morbus diabeticus (M.d) (author's transl)]. PMID- 4212526 TI - [A new rapid method for semi-quantitative determination of calcium in urine (author's transl]. PMID- 4212525 TI - [A case of reticulosis associated with macro-pyroglobulinemia (author's transl)]. PMID- 4212527 TI - [Abnormalities of insulin secretion during phreno-celiac stenosis]. PMID- 4212528 TI - [Action of asiaticoside (pentacyclic triterpene) extracted from Hydrocotyle madagascariensis on duodenal ulcers induced with mercaptoethylamine in male Wistar rats]. PMID- 4212529 TI - [Action of certain hormonal steroids on the rat pituitary gland]. PMID- 4212530 TI - [Action of drugs on phagocytosis: the atropine-acetylcholine combination]. PMID- 4212531 TI - [Action of hydroxy-9- and methoxy-9-ellipticines on HeLa S3 cells in culture in vitro]. PMID- 4212532 TI - [Action of L-arabinose ingested by lactating rats, simultaneously with a calcium salt, on the distribution of the cation between the mother and her litter]. PMID- 4212533 TI - [Activity of enzymes of intermediate protein metabolism in thio-TEPA treatment of patients with ovarian cancer]. PMID- 4212534 TI - [Acupuncture anesthesia in open heart surgery with extracorporeal circulation]. PMID- 4212535 TI - [Acupuncture anesthesia in open heart surgery with extracorporeal circulation]. PMID- 4212536 TI - [Acupuncture anesthesia in open heart surgery with extracorporeal circulation]. PMID- 4212537 TI - [Advances in endocrinology on the reproduction of domestic animals. 7. Endocrinology of labor and lactation]. PMID- 4212538 TI - [Advances in the treatment of scoliosis (author's transl)]. PMID- 4212539 TI - [Agar gel-based immunosorbents and their use in the double gel diffusion reaction]. PMID- 4212540 TI - [Amniocentesis in Rh isoimmunization and the permeation of the fetal red blood cells to the mother]. PMID- 4212541 TI - [An epidemic of typhoid fever among schoolchildren in and around of Mutsu-Shi, Aomori Pref. in winter of 1972]. PMID- 4212542 TI - [Analysis by density gradient centrifugation of DNA of E. coli K 12 lacking thymine]. PMID- 4212543 TI - [Aneurysm of the cervical carotid artery as a cause of dangerous false diagnosis (author's transl)]. PMID- 4212544 TI - [Anti-hypermagnesemic action of calcitonin in rats and goats]. PMID- 4212545 TI - [Anti-malarial agent, tripiperaquine]. PMID- 4212546 TI - [Antigenic structure of the causative agent of melioidsis and its cellular structures]. PMID- 4212547 TI - [Antitumoral effect of peritoneal macrophages activated by a water-soluble adjuvant of mycobacterial origin]. PMID- 4212548 TI - [Anton Chekhov on the island of Sachalin (author's transl)]. PMID- 4212549 TI - [Attack prevention and exacerbation therapy of the chronic bronchitis syndrome]. PMID- 4212550 TI - [Attempted separation of the surface antigens of the A-Hong Kong-1-68 H3N2 virus, using a new carboxypolypeptidase]. PMID- 4212551 TI - [Attenuation of the antigenic characteristics of human aortic valves intended for transplantation]. PMID- 4212552 TI - [Australia antigen (HB) and the corresponding antibody in mothers and their newborn infants in Dakar]. PMID- 4212553 TI - [Australia antigen in human plasma fractionation products]. PMID- 4212554 TI - [Autonomic emotional syndromes in practice: experiences of therapy with a long acting drug (author's transl)]. PMID- 4212555 TI - [Autophagy of the neurosecretory material in the posterior lobe of the pituitary of the rat at the beginning of rehydration]. PMID- 4212557 TI - [ABO blood groups in physicians more than 75 years old. On the hypothesis concerning "little more fitness of blood group O]. PMID- 4212556 TI - [Autoradiographic study of synthesis activities in the apical crest and apical fold of the limb bud in the embryo of Emys obicularis]. PMID- 4212558 TI - [Bacillary forms of Neisseria]. PMID- 4212559 TI - [Bacteremia. 2. Therapeutic effects and adverse effects of massive doses of penicillin G and cephalosporin antibiotics in subacute bacterial endocarditis]. PMID- 4212560 TI - [Bacteremic diseases. 3. Determination of antibiotic level of the blood and its clinical significance in septicaemia and bacterial endocarditis]. PMID- 4212561 TI - [Bacteriological and pathomorphological characteristics of tuberculous infection of palatine tonsils in children]. PMID- 4212562 TI - [Bacteriological study on diarrheal diseases. 1. Incidence of isolation of pathogenic bacteria in patients with diarrhea]. PMID- 4212564 TI - [Behavior of the curve of thyroid uptake of radioiodine, of blood thyroxine and of thyroxine-binding capacity of the blood in presenile and senile subjects as compared with normal young persons]. PMID- 4212565 TI - [Beta-lactam antibiotic inactivating substance of gram negative bacilli and a new biological assay method]. PMID- 4212563 TI - [Baycillin Mega--trial in general practice]. PMID- 4212566 TI - [Binding and transport of substances by serum albumin]. PMID- 4212568 TI - [Brain cerebrosides]. PMID- 4212567 TI - [Biogenic amines in chronic pancreatitis]. PMID- 4212569 TI - [Cancerogenic and cocancerogenic action of 12-0-tetradecanoyl-phorbol-13-acetate (TPA) on mouse skin]. PMID- 4212570 TI - [Case report and bacteriologic studies of Moraxella-Herellea-Mima group organisms]. PMID- 4212571 TI - [Cell types in bronchial carcinoma and their prognostic significance. A report on 1002 cases (author's transl)]. PMID- 4212572 TI - [Centenial of Walther Straub's birthday]. PMID- 4212573 TI - [Changes in the form of interdigital space in cattle during locomotion. A contribution to the analysis of movement in cattle]. PMID- 4212574 TI - [Changes in the immunoglobulin system in multiple myeloma]. PMID- 4212575 TI - [Characterization of a new type of metachromatic leukodystrophy]. PMID- 4212576 TI - [Characterization of the long-acting thyroid stimulator. Considerations on preliminary results]. PMID- 4212577 TI - [Chondro-osteoplastic tracheobronchopathy]. PMID- 4212578 TI - [Circaseptidian rhythms--about 7 days--synchronized or not with the social week]. PMID- 4212579 TI - [Clinical experience with transvenous management of pulmonary embolic disease (author's transl)]. PMID- 4212580 TI - [Clinical experience with tumors of the female urethra (author's transl)]. PMID- 4212581 TI - [Clinical picture, diagnosis and treatment of reticulosarcoma of the maxilla]. PMID- 4212582 TI - [Clinical problems in peripheral metabolic regulation]. PMID- 4212583 TI - [Clinico-bacteriological comparisons in patients after surgery of pulmonary tuberculoma]. PMID- 4212584 TI - [Clinicopathological conference: No. 18: absence of pulse, exhaustion and obstructive jaundice]. PMID- 4212585 TI - [Combined traditional Chinese and western medicine in treatment of chronic nephritis. Report of 110 cases]. PMID- 4212586 TI - [Comparative development of interdigital morphogenetic necrosis in the foot of chick and duck embryos]. PMID- 4212587 TI - [Comparative protective activities of chromone 2-carbohydroxamic acid (sodium salt), methionine and disodium tetracemate in experimental poisoning by mercuric chloride in the mouse; variations in lactate dehydrogenase (LDH) and its humoral and tissue isoenzymes (iso LDH)]. PMID- 4212588 TI - [Comparative study of the half-life of thyroxine- I 125 in the normal AG Wistar rat, the hairless mutant and the hairy hybrid]. PMID- 4212589 TI - [Comparative study of two methods of quantitative immunochemical determination (author's transl)]. PMID- 4212591 TI - [Comparison of thermostable exotoxins of different serotypes of Bacillus thuringiensis]. PMID- 4212590 TI - [Comparative testing of a new cream-base against unguentum diachylon in ulcus cruris]. PMID- 4212592 TI - [Composition of gases emitted by Clostridium aerofoetidum and Clostridium fallax cultured in a medium containing sodium thioglycolate in a vacuum, after alkalinization of the medium for cultures]. PMID- 4212593 TI - [Conditioning of the visual cortical cells of 5-week-old kittens reared with or without visual experience]. PMID- 4212594 TI - [Congenital lesions of the organ of vision in premature infants]. PMID- 4212595 TI - [Contamination with Mycobacterium tuberculosis of certain environmental objects within the foci of tuberculosis]. PMID- 4212596 TI - [Contribution to the rationalization of the calculation of distribution dose in telecurietherapy. II. Pendelum technique (author's transl)]. PMID- 4212597 TI - [Convulsive seizures in autostimulation during the period of sensitivity to audiogenic seizure in DBA-2 mice]. PMID- 4212598 TI - [Corpus callosum and visual cortex]. PMID- 4212599 TI - [Course and treatment of severe form of acute relapsing pancreatitis in an adolescent girl]. PMID- 4212600 TI - [Current status of the treatment of cheilognathopalatoschisis (author's transl)]. PMID- 4212601 TI - [Decrease of the incorporation of cholesterol-C 14 in the aorta after administration of dimethylbiguanide in normal rabbits]. PMID- 4212602 TI - [Demonstration by light microscopy of the terminal degeneration of afferents of inferior olivary origin in the lateral vestibular (Deiter's) nucleus of the rat]. PMID- 4212603 TI - [Demonstration of a phenolic amine in various orchids of the Cattleya genus]. PMID- 4212604 TI - [Demonstration of extracellular leucine aminopeptidases (EC 3.4.1) of Aspergillus oryzae (IP 410). Study of the leucine aminopeptidase 2 fraction]. PMID- 4212605 TI - [Demonstration of surface antigens in BHK 21 cells infected with FV 3 (frog virus 3), using the mixed agglutination technic]. PMID- 4212606 TI - [Demonstration of the presence of membrane immunoglobulins on human lymphocyte villosities]. PMID- 4212607 TI - [Desensitization of the guinea pig ileum to scorpion venom by various concentrations of ions in the external medium]. PMID- 4212608 TI - [Detection of a thrombotic tendency by means of coagulation tests (author's transl)]. PMID- 4212609 TI - [Determination of carbaryl cumulation]. PMID- 4212610 TI - [Determination of dissolved blood nitrogen by gas-phase chromatography]. PMID- 4212611 TI - [Determination of intracellular activity of Mycobacterium tuberculosis in cell culture]. PMID- 4212612 TI - [Determination of the amount of specific antibodies in precipitated sera and enzymatic cleavage of immune precipitates]. PMID- 4212613 TI - [Development of endometrioses in episiotomy cicatrix]. PMID- 4212614 TI - [Differentiation in the initial steps of development]. PMID- 4212615 TI - [Diphtherial bacteriophage in the pharynx of carriers]. PMID- 4212616 TI - [Disodium cromoglycate in the treatment of asthmatic syndrome]. PMID- 4212617 TI - [Disorder of regulation of parathyroid activity in anephric rats]. PMID- 4212618 TI - [Disorders of glycoregulation during phreno-celiac stenoses]. PMID- 4212619 TI - [Distribution of drug consumption between the sexes in young people (author's transl)]. PMID- 4212621 TI - [Drug resistance in Plasmodium and the development of antimalarial agents]. PMID- 4212620 TI - [Distribution of ABO blood groups and Rh factors in a large population sample of Milan]. PMID- 4212622 TI - [Duodenoscopy. Comparative study with radiology and directed biopsy]. PMID- 4212623 TI - [Dynamics of alcaline phosphatase activity in supernatants of liver homogenates and in the serum of pheasants (Phasianus colchicus L.) during the first 3 months of life and in adult pheasants]. PMID- 4212624 TI - [Dysglobulinemia]. PMID- 4212625 TI - [Dyskinesia underlying esophageal diverticula. Therapeutic results]. PMID- 4212626 TI - [Early diagnosis of phlebothromboses of the leg with the radiofibrinogen test in patients with alloplastic hip joint replacement (author's transl)]. PMID- 4212627 TI - [Early orthodontic treatment of continuous cheilognathouranoschisis (author's transl)]. PMID- 4212628 TI - [Early pulmonary emphysema and alpha 1 antitrypsine deficiency. Study on 222 cases with respiratory insufficiency]. PMID- 4212629 TI - [Early synthesis of a messenger type RNA from keratin by early chick embryo skin]. PMID- 4212630 TI - [Echocardiography: clinical use--advantages--limitations (author's transl)]. PMID- 4212631 TI - [Editorial: Deep thromboses of leg and pelvic veins II]. PMID- 4212632 TI - [Effect of a steady magnetic field on Mycobacterium tuberculosis]. PMID- 4212633 TI - [Effect of beta pyridylcarbinol on blood sugar, insulin, potassium, free fatty acids and hematocrit in the miniature pig]. PMID- 4212634 TI - [Effect of dysproteinemias on the in-vitro diagnosis of thyroid function]. PMID- 4212635 TI - [Effect of giving various Mn or Cu supplements in Zinc deficiency]. PMID- 4212636 TI - [Effect of glucocorticoid therapy on the indicators of biologically active substances in the blood of children with bronchial asthma]. PMID- 4212637 TI - [Effect of ingestion of hydrogenated colza oil on corporal lipids of different tissues in the rat]. PMID- 4212638 TI - [Effect of iprazid and transamine on brain metabolism of glycogen and its different forms]. PMID- 4212640 TI - [Effect of small doses of ethanol and nitroglycerine on the duration of heart cycle phases]. PMID- 4212639 TI - [Effect of isoproterenol on the systemic circulation of a dog with cardiopulmonary bypass]. PMID- 4212641 TI - [Effects and side-effects of immunosuppressive therapy in various dermatoses (author's transl)]. PMID- 4212642 TI - [Effects of cromoglycate on allergic skin tests]. PMID- 4212643 TI - [Effects of 2 metabolites of testosterone, alpha- and 3 beta-androstanediol on the activity of the epididymis of the castrated lizard in organ culture]. PMID- 4212644 TI - [Electrocardiography in sheep with reference to breed, age and other influencing factors]. PMID- 4212645 TI - [Ensuring prevention of Rh immunization by the transfusion service]. PMID- 4212646 TI - [Epidemic cerebro-spinal meningitis. Realities and tendencies]. PMID- 4212647 TI - [Epidemics caused by Pseudomonas aeruginosa in 2 neonatal wards]. PMID- 4212648 TI - [Epidemiology and social medical importance of diseases of the veins (author's transl)]. PMID- 4212650 TI - [Evaluation of antipyretic effect of mefenamic acid--a double blind test]. PMID- 4212649 TI - [Erythromycin in the treatment of intestinal amibiasis and other processes of the digestive tract]. PMID- 4212651 TI - [Evaluation of preservative substances for the prevention of microbial growth in the urine]. PMID- 4212652 TI - [Excretion of thiophosphamide and cyclophosphane in lung cancer patients]. PMID- 4212653 TI - [Experimental basis of using the staphylococcal test for the control of disinfection in foci of air-borne droplet infections]. PMID- 4212655 TI - [Fabry's disease]. PMID- 4212654 TI - [Extensive, generalized form of saturnine paralysis]. PMID- 4212656 TI - [Familial neuroblastoma of the suprarenal glands in the newborn (author's transl)]. PMID- 4212657 TI - [Fetomaternal immunization of pregnant women to HL-A alloantigens and ABO and Rh antigens. II. Clinical observations on the course of pregnancy]. PMID- 4212658 TI - [Fluorescence study of nucleic acids extracted from cells in cultures treated with methyl-7-benzo(a)anthracene]. PMID- 4212659 TI - [Frequency of choledocholithiasis in 3155 cholecystectomies]. PMID- 4212660 TI - [Further tests of the action of testosterone on the development of Muller's ducts of the bird embryo in culture in vitro]. PMID- 4212662 TI - [General trends in Haematology. Geographical haematology (author's transl)]. PMID- 4212661 TI - [Gastric diverticulae. Report of 4 cases]. PMID- 4212663 TI - [Genesis and biochemistry of ruminant acidosis. 2. Microorganisms and metabolism of lactic acid isomers]. PMID- 4212664 TI - [Genetic determinism of the mechanisms controlling autostimulation behavior in mice: preliminary analysis]. PMID- 4212665 TI - [Gonorrhoea in young women admitted to a gynaecology department]. PMID- 4212666 TI - [Haemophilus aphrophilus endocarditis: bacteriological and clinical study of the first 3 cases discovered in Japan]. PMID- 4212668 TI - [Hemophilia BM (abnormal factor IX in coagulation disorder) (author's transl)]. PMID- 4212667 TI - [Hemopexin levels of men and women in different age-groups (author's transl)]. PMID- 4212669 TI - [Hormonal stimulation of ovarian adenyl cyclase in the rat and a teleost fish (Carassius auratus): influence of adenosine triphosphate concentration]. PMID- 4212670 TI - [Identification of the W chromosome in Japanese quail, Coturnix coturnix japonica]. PMID- 4212671 TI - [Immunochemical activity of different isoelectric zones of diphtheria and tetanus antitoxins in immune sera]. PMID- 4212672 TI - [Immunological reactivity of poly I:C-DEAE dextran complexes]. PMID- 4212674 TI - [In vivo models on the penetration of aminoacids through the wall of the rumen. 1. Amino acid transfer in the empty washed rumen]. PMID- 4212673 TI - [Improvement of dose distribution in conformation irradiation of cervical carcinoma]. PMID- 4212675 TI - [Incidence of drug sensitivity decrease in tuberculosis bacteria in untreated tuberculoses using autopsy material]. PMID- 4212676 TI - [Incidence of embolic cerebrovascular accidents in chronic Chagas' cardiopathies]. PMID- 4212677 TI - [Incorporation of cis and trans monoenic acids into various rat tissues after ingestion of refined and hydrogenated colza oil]. PMID- 4212678 TI - [Increase in connective tissue permeability during experimental lathyrism]. PMID- 4212679 TI - [Induction of morpholigical anomalies by ultraviolet irradiation in a strain of Streptomyces fradiae]. PMID- 4212680 TI - [Influence of a new oral hypoglycemic product (glibenclamide-phenformin) on some aspects of lipid metabolism]. PMID- 4212681 TI - [Influence of the administration of organo-halogenated pesticides and of polychloro-biphenyls on the metabolism of zoxazolamine in the rat]. PMID- 4212682 TI - [Influence of the humidity of the air on the sensation of heat indoors]. PMID- 4212683 TI - [Influence of the water content of rice seeds on their sensitivity of cobalt 60 radiation]. PMID- 4212684 TI - [Influences of various biological odors on the emotional behavior of rats placed in a "space devoid of information"]. PMID- 4212685 TI - [Inhalation allergies to detergent proteases in consumers]. PMID- 4212686 TI - [Inhibition of the hypercalcemic effect of endogenous parathyroid hormone by its azo derivative in the EDTA test]. PMID- 4212687 TI - [Inhibition of uterine contraction in labor by prostaglandin antagonists in threatened abortion, premature labor and normal labor]. PMID- 4212688 TI - [Innervation of the urinary tract in vertebrates and man]. PMID- 4212689 TI - [Insulin deficiency and its metabolic sequelae. Laboratory diagnosis of ketonic acidosis]. PMID- 4212690 TI - [Interrelationship between pyelonephritis and chronic tonsillitis]. PMID- 4212691 TI - [Intraluminal duodenal diverticulum in a child]. PMID- 4212692 TI - [Is disulfiram treatment still indicated today? (author's transl)]. PMID- 4212694 TI - [Laboratory diagnosis of meningococcal infection]. PMID- 4212693 TI - [Isolation of mutants resistant to antituberculous drugs in wild strains of M. bovis]. PMID- 4212695 TI - [Lipid mobilization and erythropoietic stimulation caused by anemia in rabbits. Inhibitory effects of thyroidectomy]. PMID- 4212696 TI - [Localization of a structural locus of alpha-galactosidase on the X chromosome, using the human-hamster cell hybridization method]. PMID- 4212697 TI - [Localization of IgA, IgG, IgM immunoglobulins during disc electrophoresis in polyacrylamide gel]. PMID- 4212698 TI - [Localized diffusion of substances absorbed through the skin]. PMID- 4212699 TI - [Long-term study on the anti-rigidity effect of L-dopa and a decarboxylase inhibitor (ro 8-0576) (author's transl)]. PMID- 4212700 TI - [Mechanism of eructation in sheep. I. Determination of eructated gases]. PMID- 4212701 TI - [Menigitis due to Moraxella osloensis (author's transl)]. PMID- 4212702 TI - [Meningitis in childhood, recent aspects]. PMID- 4212703 TI - [Metabolic characteristics of regimens of artificial pulmonary ventilation]. PMID- 4212705 TI - [Metabolism of glycerol]. PMID- 4212704 TI - [Metabolic investigations during continuous infusion of glucose, fructose, and xylitol over 48 hours (author's transl)]. PMID- 4212706 TI - [Methadone inhibition of central vagal pancreatic stimulation induced by 2-deoxy D-glucose]. PMID- 4212708 TI - [Methods of detection and diagnosis of minor forms of tuberculosis in children and adolescents]. PMID- 4212707 TI - [Methods of demonstration and distribution of pectinolytic activity in Bacillus species]. PMID- 4212709 TI - [Mode of transmission and experimental specificity of Acanthocephalus anthuris (Acanthocephala)]. PMID- 4212710 TI - [Modern treatment of skin tuberculosis]. PMID- 4212711 TI - [Modifications of membrane antigen reactivity in PNH-like erythrocytes (author's transl)]. PMID- 4212712 TI - [Mollusca of the sub-genus Bulinus s.s. (Basommatophora: Planorbidae), intermediary hosts of various trematodes, parasites of domestic ruminants in Ethiopia]. PMID- 4212714 TI - [Multiple chromosomal polymorphism in Taterillus of the Niger (Rodentia, Gerbillidae)]. PMID- 4212713 TI - [Morphologic and morpho metric comparative studies on the hand-skeleton of recent primates. I]. PMID- 4212716 TI - [Myringoplasty]. PMID- 4212715 TI - [Myeloma and "related" gammapathies]. PMID- 4212717 TI - [Necrotizing external otitis]. PMID- 4212718 TI - [New concepts in the physiology and pathology: the probable role of dopaminergic neurons in the regulation of the growth of the adenohypophysis]. PMID- 4212720 TI - [Normal immunoglobulins in different forms of monoclonal immunoglobulinopathies]. PMID- 4212719 TI - [New possibilities in the immunological diagnosis of treponema infection (syphilis)]. PMID- 4212721 TI - [Note on the ultrastructural localization of thiaminepyrophosphatase in the prenatal mouse liver]. PMID- 4212722 TI - [On a case of supernumerary metacentric chromosome. Clinical aspects]. PMID- 4212723 TI - [On some biological effects of nitroso derivatives]. PMID- 4212724 TI - [On the migratory activity of germ cells of mice subjected to the attraction of the germinal epithelium of the chick embryo in culture in vitro]. PMID- 4212725 TI - [Operative treatment of acute venous thrombosis of the leg and pelvis (author's transl)]. PMID- 4212726 TI - [Operative treatment of knee arthrosis in the elderly (author's transl)]. PMID- 4212727 TI - [Orthopedic problems of disordered function of the hand (author's transl)]. PMID- 4212728 TI - [Orthopedics. Introduction. Developments and trends in orthopedics]. PMID- 4212729 TI - [Outbreak of scarlet fever in a kindergarten in Tachikawa city]. PMID- 4212730 TI - [Own observations on the action of glibenclamide (Daonil) in diabetes]. PMID- 4212731 TI - [Oxidative phosphorylation of rat hepatic mitochondria in the presence of tricyclic derivatives. Study of molecules belonging to the phenothiazine, iminodibenzyl, thioxanthene and thiophenylpyridylamine series]. PMID- 4212732 TI - [Panendoscopy with the Olympus GIF type D gastrointestinal fiberscope. Its value in the integral examination of the upper digestive tract]. PMID- 4212733 TI - [Participation of "furrowed cells" in the synthesis of collagen and glycoproteins in Helix aspera M. (pulmonate gastropod)]. PMID- 4212734 TI - [Pathogenesis of focal epilepsy]. PMID- 4212736 TI - [Pathology of leprosy in comparison with tuberculosis]. PMID- 4212735 TI - [Pathogenicity for lambs, of Sarcocystis tenella sporocysts isolated from canine feces. Short communication]. PMID- 4212737 TI - [Pathomorphological analysis of kidney biopsies in the hypertensive form of chronic glomerulonephritis]. PMID- 4212738 TI - [Peculiarities of the pathophysiology of operation trauma in childhood (author's transl)]. PMID- 4212739 TI - [Pediatric indications of the surgeon]. PMID- 4212740 TI - [Peripheral course of the afferent fibers from the superior oblique muscle in the cat]. PMID- 4212741 TI - [Peritonitis in the neonate, in infancy and childhood (author's transl)]. PMID- 4212742 TI - [Pharyngo-esophageal diverticula]. PMID- 4212743 TI - [Phlegmasia coerulea (author's transl)]. PMID- 4212744 TI - [Phospholipid composition of asporogenic mutants of Bacillus subtilis]. PMID- 4212745 TI - [Possibilities and limitations of outpatient operations in childhood (author's transl)]. PMID- 4212746 TI - [Possibilities and limits of antibiotic prevention in surgery of the newborn]. PMID- 4212747 TI - [Possibilities of operative treatment of children with exstrophy of the bladder (author's transl)]. PMID- 4212748 TI - [Possibilities of serum heterozygote tests in genetic mucopolysaccharidoses]. PMID- 4212749 TI - [Pre-arthrosis and its operative treatment (author's transl)]. PMID- 4212750 TI - [Preliminary report on the treatment of cancer of the uterine cervix]. PMID- 4212751 TI - [Preparation of a brain-specific protein (S100 protein) and production of a monospecific immune serum]. PMID- 4212752 TI - [Principles of radiologic treatment of pulmonary tumors]. PMID- 4212753 TI - [Problems of IgM-toxoplasma-antibody tests for the diagnosis of intra-uterine infection (author's transl)]. PMID- 4212754 TI - [Proccedings: Inherent complications of intensive therapy]. PMID- 4212755 TI - [Proceedings: Acute abdomen following post-traumatic pancreatitis]. PMID- 4212756 TI - [Proceedings: Acute renal insufficiency]. PMID- 4212757 TI - [Proceedings: Blunt abdominal injury in polytraumatization]. PMID- 4212758 TI - [Proceedings: Causes of various deficiencies in the digestive absorption of penicillin]. PMID- 4212759 TI - [Proceedings: Cercaria: dermatitis--a parasitosis of domestic bathing waters]. PMID- 4212760 TI - [Proceedings: Epidural hematoma in posterior cranial fossa]. PMID- 4212761 TI - [Proceedings: Functional of positioning treatment, reposition and fixation]. PMID- 4212762 TI - [Proceedings: Indications for conservative and surgical treatment of bone fractures. General information on the indication]. PMID- 4212763 TI - [Proceedings: Injuries of small intestine in the scope of intraabdominal combination injuries]. PMID- 4212764 TI - [Proceedings: Intensive follow-up and intensive therapy of severe cranio-cerebral injuries]. PMID- 4212765 TI - [Proceedings: Intensive medicine in acute pancreatitis, internal medicine report]. PMID- 4212767 TI - [Proceedings: Liver failure]. PMID- 4212766 TI - [Proceedings: Intensive medicine in acute pancreatitis, surgical report]. PMID- 4212769 TI - [Proceedings: Postoperative emergencies in endocrinology]. PMID- 4212768 TI - [Proceedings: Organic changes and fluctuation of the sensitivity threshold of the rat vas deferens caused by denervation]. PMID- 4212770 TI - [Proceedings: Radioimmunologic determination of parathyroid hormone under clinical conditions]. PMID- 4212771 TI - [Proceedings: Renal excretion of mineral oil constituents in fuel oil intoxication]. PMID- 4212772 TI - [Proceedings: Respiratory-, shock-, and transfusion lung]. PMID- 4212773 TI - [Proceedings: Retroperitoneal duodenal rupture in the child]. PMID- 4212774 TI - [Proceedings: Scientific and technical viewpoints on artificial organs and limbs and on function substitution]. PMID- 4212775 TI - [Proceedings: Therapeutic problems in liver rupture hemorrhages difficult to arrest]. PMID- 4212776 TI - [Proceedings: Therapy of respiratory insufficiency]. PMID- 4212777 TI - [Proceedings: Treatment of severe cranio-cerebral injuries at a main-effort hospital with special reference to intensive care and rehabilitation]. PMID- 4212778 TI - [Proceedings: Use of metals or plastics and problems involved]. PMID- 4212779 TI - [Proceedings: Use of the peroral TRH-T4 test in endocrinologic diagnosis]. PMID- 4212780 TI - [Proceedings: Value of diagnostic peritoneal lavage for surgical indication of acute abdomen caused by trauma]. PMID- 4212781 TI - [Proceedings: 450 bladder carcinomas--5 years later]. PMID- 4212782 TI - [Prognosis of epilepsy]. PMID- 4212783 TI - [Prognostic value of papanicolaou 3 findings (author's transl)]. PMID- 4212784 TI - [Proliferation capacity of (CFU-s) cell strains of the spleen of leukemic mice with Friend's leukemia]. PMID- 4212785 TI - [Prophylaxis of pulmonary embolism by interruption of the vena cava (author's transl)]. PMID- 4212786 TI - [Prophylaxis of recurrent goiter. Surgical and medical points of view (author's transl)]. PMID- 4212787 TI - [Pseudo-acute abdomen in cirrhosis of the liver (author's transl)]. PMID- 4212788 TI - [Psychotic manifestations in children--II. Epilepsies (author's transl)]. PMID- 4212789 TI - [Purification of aldolase C from brain and demonstration of its microheterogeneity]. PMID- 4212790 TI - [Pyruvate carboxylase of Pseudomonas aeruginosa. Purification and properties (author's transl)]. PMID- 4212791 TI - [Quantitative changes in the intestinal microflora of the rabbit after ligation of the pancreatic duct]. PMID- 4212792 TI - [Quantitative determination of fraction A of human hemoglobin using electrophoretic separation on cellogel and the pseudo-peroxide reaction]. PMID- 4212793 TI - [Reactivation by aliphatic alpha-hydroxyimino-ketones of plasma cholinesterases inhibited by diisopropylfluorophosphate, in Wistar rats]. PMID- 4212794 TI - [Rehabilitation of the patient with heart disease]. PMID- 4212795 TI - [Renal calcium "mud". Report of 6 cases (author's transl)]. PMID- 4212796 TI - [Renal electrolyte changes by allopurinol. A contribution in the prophylaxis of oxalic acid stones (author's transl)]. PMID- 4212797 TI - [Residual toxicity of meats and livers from calves treated with various hormones. Total results]. PMID- 4212798 TI - [Respiration of rat hepatic mitochondria in the presence of tricyclic derivatives. Study of molecules belonging to the phenothiazine, iminodibenzyl, thioxanthene and thiophenylpyridylamine series]. PMID- 4212800 TI - [Results of lysotyping in impetigo contagiosa staphylogenes within a school community]. PMID- 4212799 TI - [Results of antibiotic treatment. "What goes up must come down"]. PMID- 4212802 TI - [Rifampin concentration and its dynamics in the blood of patients with pulmonary tuberculosis]. PMID- 4212801 TI - [Results of some neuroendocrinological studies in patients with anatomically verified hypothalamic disorders]. PMID- 4212803 TI - [Role of the state of the central nervous system in the action of cholinergic agents on arterial pressure in cats]. PMID- 4212804 TI - [Ruminoreticulum motility. IV. Intraruminal pressure during the reticulum-rumen cycle and during eructation]. PMID- 4212805 TI - [Selective action of neuroleptics on the cholinergic neurons of the neostriatum in the rat: antagonism to apomorphine]. PMID- 4212806 TI - [Semi-quantitative determination of the immune globulins IgM and IgA in the cord blood of 1000 newborns for early recognition of intra-uterine infection (author's transl)]. PMID- 4212807 TI - [Sensitivity of meningococci against antibiotics]. PMID- 4212808 TI - [Sensitivity to catecholamines of isolated chick embryo cardiomyoblasts in culture in vitro]. PMID- 4212809 TI - [Sensitivity to penicillin of gonococcal strains cultured from cases of acute untreated gonorrhea in the Szczecin region]. PMID- 4212810 TI - [Septicemia in pediatric surgery. Disposition, causes and clinical picture (author's transl)]. PMID- 4212811 TI - [Septicemia in premature infants through Klebsiella aerobacter and Pseudomonas]. PMID- 4212812 TI - [Serum concentrations of immunoglobulins IGG, IGM and IGA during normal pregnancy (author's transl)]. PMID- 4212813 TI - [Serum transferrin, protein intake, and iron metabolism in regular hemodialysis patients (author's transl)]. PMID- 4212814 TI - [Sick sinus node syndrome. Report of 2 cases]. PMID- 4212815 TI - [Signes of adaptation under long-term combined antituberculous therapy (author's transl)]. PMID- 4212816 TI - [Significance of pyramidal system in animal motor behavior]. PMID- 4212817 TI - [Significance of the eggshell structure for the egg content]. PMID- 4212818 TI - [So-called conditionally pathogenic microorganisms (a review)]. PMID- 4212819 TI - [Stereotaxic surgery for epilepsy]. PMID- 4212820 TI - [Stereotoxic surgery for heavy pain, untreatable by other methods]. PMID- 4212821 TI - [Stimulation test with the use of TRH in the diagnosis of thyroid gland pathology]. PMID- 4212823 TI - [Strychnine nitrate in treatment of chronic aplastic anemia]. PMID- 4212822 TI - [Stimulation with testosterone of the ventral prostate of the castrated rat in organ culture]. PMID- 4212824 TI - [Studies on whole-body counter (1). A new technique for uniform response with two crystal scanning method (author's transl)]. PMID- 4212825 TI - [Study of anti-mononucleotide and anti-dinucleotide antibodies]. PMID- 4212826 TI - [Study of colonies of a stable variant of Bacillus thuringiensis (Berliner) resistant to aflatoxin B 1]. PMID- 4212827 TI - [Study of genetic variants of alpha 1-antitrypsin in bidimensional immuno electrofocusing]. PMID- 4212828 TI - [Study of hypoxanthine dehydrogenase of the vitelline sac of the embryonated chicken egg]. PMID- 4212830 TI - [Study of parasite reduction in different natural or experimental filariasis vectors]. PMID- 4212829 TI - [Study of membrane rectification phenomena of striated muscle fibers of the crab (Carcinus maenas)]. PMID- 4212831 TI - [Study of plasma clearance of ceruloplasmin and apoceruloplasmins in normal humans]. PMID- 4212832 TI - [Study of potential pathogenic properties of chromogenic mutants of Mycobacterium tuberculosis and certain atypical Mycobacteria]. PMID- 4212833 TI - [Study of some parameters intervening in a delayed hypersensitivity test in the mouse]. PMID- 4212834 TI - [Study of survival, after preservation at low temperature, of human aortic valves for transplantation]. PMID- 4212836 TI - [Study of the mechanism of biochemical action of a platinum complex with carcinostatic effect: ammonium hexachloroplatinate (PtCl 6 (NH 4)2]. PMID- 4212835 TI - [Study of the interaction of L-transformed Brucella with a culture of peritoneal macrophages]. PMID- 4212837 TI - [Study of the mother-offspring relation in sheep (Ovis aries) at the time of suckling]. PMID- 4212839 TI - [Subsepsis allergica. A clinical type of rheumatoid disease]. PMID- 4212838 TI - [Study of the tensio-active power of some proteins-bacteriocins]. PMID- 4212840 TI - [Successful attempt at anti-Rh immunization prevention by administration of anti D-Kabi immunoglobulin following incompatible blood transfusion]. PMID- 4212842 TI - [Surgical diagnosis of bleeding diverticuli of the duodenum]. PMID- 4212843 TI - [Surgical problems posed by duodenal diverticula (author's transl)]. PMID- 4212841 TI - [Superoxide dismutase. Function and concentration of erythrocupreine in normal humans]. PMID- 4212844 TI - [Surgical treatment of intrapancreatically situated diverticula of the duodenum]. PMID- 4212845 TI - [The effect of lithium therapy on the human thyroid and its function (author's transl)]. PMID- 4212847 TI - [The following of a diabetic patient treated by Euglucan]. PMID- 4212846 TI - [The external treatment of dermatoses (author's transl)]. PMID- 4212849 TI - [The health care model at the Ulleraker hospital]. PMID- 4212848 TI - [The glibenclamide-phenformin combination in the therapy of diabetes mellitus]. PMID- 4212850 TI - [The hungry child in the world today (author's transl)]. PMID- 4212851 TI - [The importance of cerebral angiography in cranio-cerebral trauma (author's transl)]. PMID- 4212852 TI - [The importance of thrombocytes for thrombogenesis and the pharmacological influencing of thrombocyte function (author's transl)]. PMID- 4212853 TI - [The influence of different fixation methods and agents on the electron microscopical structure of the vascular stria, the spiral ligament and the spiral prominence in guinea-pigs (author's transl)]. PMID- 4212854 TI - [The influence of proteolytic enzyme activity from cultures of Bacillus subtilis on decalcified dental tissue]. PMID- 4212856 TI - [The intestinal transfer of bivalent cations: effects on the absorption of Ca-45 of increasing doses of L-arabinose ingested simultaneously with that mineral]. PMID- 4212855 TI - [The influences of various fixative-methods on the crista ampullaris of the guinea pig (author's transl)]. PMID- 4212857 TI - [The local immune response in experimental airborne influenza of Balb-c mice infected with myxovirus influenzae A-Hong-Kong-1-68 (H3N2) (author's transl)]. PMID- 4212858 TI - [The pituitary gland is without influence on the synthesis of estrogens in the chick embryo]. PMID- 4212859 TI - [The presence in some human sera of anti-IgD antibodies (author's transl)]. PMID- 4212860 TI - [The present position of joint substitution (author's transl)]. PMID- 4212861 TI - [The role of medical science in nutrition research]. PMID- 4212862 TI - [The treatment of chronic hepatitis (author's transl)]. PMID- 4212863 TI - [The treatment of severe hip joint fractures (author's transl)]. PMID- 4212864 TI - [The whole body gamma counter]. PMID- 4212865 TI - [Therapeutic use of thyreotropin releasing hormone in hypophyseal dwarfism with secondary hypothyreosis]. PMID- 4212867 TI - [Thermography in deep phlebothrombosis of the leg (author's transl)]. PMID- 4212866 TI - [Therapy of intrathoracic insufficiency of anastomoses in esophagogastro- or esophagojejunostomy]. PMID- 4212868 TI - [Transfer of resistance to antibiotics and sulfonamides from Shigella dysenteriae 1 (Shiga bacillus) to Escherichia coli K 12]. PMID- 4212869 TI - [Tuberculous meningitis and BCG vaccination (author's transl)]. PMID- 4212870 TI - [TRH stimulation test with age and sex specific TSH response in normal subjects (authors' transl)]. PMID- 4212871 TI - [Upper-arm fistula for chronic haemodialysis (author's transl)]. PMID- 4212872 TI - [Ureteral stenosis in childhood, recognition, treatment and results]. PMID- 4212873 TI - [Use of anabolic steroids in therapy]. PMID- 4212874 TI - [Use of bio-electric impedance in the detection and localization of air bubbles in tissues]. PMID- 4212875 TI - [Valence and affinity of anti-hapten IgM antibodies]. PMID- 4212876 TI - [Variations in the aspartate-ammonium lyase activity of Pseudomonas fluorescens as a function of composition of the culture medium]. PMID- 4212877 TI - [Virulence of Brucella abortus species L forms for guinea pigs]. PMID- 4212878 TI - [Work capacity improvement during the course of outpatient rehabilitation following myocardial infarction (author's transl)]. PMID- 4212879 TI - [50th convention of the Association of Bavarian Surgeons in Munich, July 19-21, 1973]. PMID- 4212881 TI - [91st convention of the German Surgical Society in Munich, May 8-11, 1974]. PMID- 4212880 TI - [51Cr-EDTA and endogenous creatine clearance studies]. PMID- 4212882 TI - A case of neurilemmoma in the mandible. PMID- 4212883 TI - A comparison of cortical functions in man and the other primates. PMID- 4212884 TI - A double-blind crossover trial of disodium cromoglycate in asthmatic patients living under environmental control. PMID- 4212885 TI - A fine structural study on the extracellular activity of alkaline phosphatase and its role in calcification. PMID- 4212886 TI - A fragment from the constant portion of IgG obtained by peptic digestion at high temperatures. PMID- 4212887 TI - A hazy ('bull's eye') plaque variant of bovine viral diarrhea virus. PMID- 4212888 TI - A hominid mandible from East Rudolf, Kenya. PMID- 4212889 TI - A method for alpha-L-iduronidase assay. PMID- 4212890 TI - A new method for measuring the stress effects in minor oral surgery. PMID- 4212891 TI - A note on the adjustment of rates. PMID- 4212893 TI - A precursor of the neck appendage protein of B. subtilis phage phi 29. PMID- 4212892 TI - A pleiotropic mutation affecting expression of polar development events in Caulobacter crescentus. AB - A developmental mutant of C. crescentus with altered polar surface structures has been isolated. The mutant lacks a flagellum and pili, and may have an abnormal DNA phage receptor site. A revertant regains the normal structures simultaneously. This point mutation allows normal flagellin synthesis, stalk formation, equatorial cell division, and rate of growth. The mutant phenotype indicates that the assembly of the polar surface structures is coordinately regulated and independent of mechanisms regulating cell polarity and division. PMID- 4212894 TI - A pteridine adsorbent for affinity chromatography. PMID- 4212895 TI - A quantitative method for analysing competition where individuals cannot be identified. PMID- 4212896 TI - A rapid method for the separation of guinea pig IgGl and IgG2. PMID- 4212897 TI - A rapid procedure for the radioimmunoassay of rat growth hormone. PMID- 4212898 TI - A reinterpretation of research on aggression. PMID- 4212901 TI - A sporulation medium for Bacillus anthracis. PMID- 4212902 TI - A stochastic locomotor control model for the goldfish (Carassius auratus). PMID- 4212899 TI - A salmonellosis outbreak in New York City attributed to a catering establishment. PMID- 4212903 TI - A study of the ultrastructure of human basophil leukocytes. PMID- 4212904 TI - A technique for standardizing the jet injector and Mantoux tuberculin skin tests. PMID- 4212905 TI - Abdominal wound infections and plastic wound guards. PMID- 4212907 TI - Absence of disulfide bridges between heavy and light chains in IgA from chicken bile. PMID- 4212906 TI - Abortion and menstrual extraction for the ambulatory patient. PMID- 4212908 TI - Accumulation of tritiated thyrotropin releasing hormone in different organs, especially in the thyroid. PMID- 4212909 TI - Activation by ferrous ions of an alpha-mannosidase in rat testis and liver. PMID- 4212910 TI - Active avoidance and discrimination learning in rats with protein or calorie deficit and centrophenoxine or palmitoyl ethanolamide treatment in early postnatal life. PMID- 4212911 TI - Activity and sexual behavior of neurological mutants in Drosophila melanogaster. PMID- 4212912 TI - Acute myeloblastic leukemia after cure of ovarian cancer. PMID- 4212913 TI - Acute myeloproliferative disorder following long-term chlorambucil therapy. PMID- 4212914 TI - Adreno-leukodystrophy (sex-linked Schilder's disease). A pathogenetic hypothesis based on ultrastructural lesions in adrenal cortex, peripheral nerve and testis. AB - Striated adrenal cells in the zona reticularis and inner fasciculata apparently constitute the initial adrenolytic lesion in patients with adreno-leukodystrophy (ALD). Cytoplasmic ballooning and macrovacuolization develop after the striations, and probably represent exaggerated responses to adrenocorticotropin (ACTH). Intracytoplasmic lamellae and lamellar-lipid profiles, containing a free 3beta-hydroxysterol, are the ultrastructural correlates of the striations seen with the light microscope. The ultrastructural demonstration of intracytoplasmic lamellae and lamellar-lipid profiles in adrenal striated cells, testicular interstitial cells, Schwann cells and brain macrophages from patients with ALD provides further morphologic evidence for a systemic metabolic defect common to the nervous and endocrine systems. In our experience, adrenal biopsy has proven to be the most effective procedure for the diagnosis of adreno-leukodystrophy. An hypothesis proposing a membrane abnormality affecting its stability and turnover might explain the concomitant destruction of adrenal cortex and brain in these patients. PMID- 4212915 TI - Airborne infection. PMID- 4212916 TI - Albumin, immunoglobulin A and G concentrations in sputum during and after status asthmaticus. PMID- 4212917 TI - Aldosterone secretion in infantile malnutrition. PMID- 4212919 TI - Allograft tolerance in the absence of circulating antibodies. PMID- 4212918 TI - Aldosterone-induced protein in toad urinary bladder. AB - Simultaneous electrophysiological and biochemical experiments demonstrated a specific aldosterone-induced protein in paired urinary hemibladders isolated from the toad Bufo marinus. Whenever aldosterone stinlmulated short-circuit current, aldosterone specifically increased [(35)S] methionine incorporation into a low molecular-weight protein (about 12,000). Comparative studies with dexamethasone and insulin and inhibitory studies with spironolactone and actinomycin D suggest mineralocorticoid specificity. PMID- 4212920 TI - Alpha 1-antitrypsin in septic infections during infancy. PMID- 4212922 TI - Alpha1-antitrypsin and its deficiency. PMID- 4212921 TI - Alpha1 antitrypsin deficiency and liver disease in childhood: genetic, immunochemical, histological, and ultrastructural diagnosis. AB - alpha(1) Antitrypsin deficiency is a significant factor in the pathogenesis of neonatal cholestasis and progressive juvenile cirrhosis. The diagnosis may be suggested by the liver biopsy appearances and confirmed by immunochemical analysis of the serum. Genetic counselling of affected families is of importance, as medical treatment is ineffective at the present time. PMID- 4212923 TI - Alteration of antigenic components of rat parotid gland following denervation. PMID- 4212925 TI - Alteration of nociception by stimulation of cerebellar structures in the monkey. PMID- 4212924 TI - Alteration of epididymal function and its relation to maturation of spermatozoa. PMID- 4212926 TI - Alterations in circulating thyroid hormones and thyrotropin in hepatic cirrhosis: evidence for euthyroidism despite subnormal serum triiodothyronine. PMID- 4212927 TI - Amino acid sequence studies of human IgA myeloma proteins. PMID- 4212928 TI - An assessment of provider behavior in shared professional facilities. PMID- 4212929 TI - An experimental study on the effect of local hemostatics on bone healing in rabbits. PMID- 4212931 TI - An idiotypic cross-reaction between two streptococcal antibodies from an individual rabbit. PMID- 4212932 TI - An immunochemical characterization of the phytochrome destruction reaction. PMID- 4212933 TI - An improved method for liquid scintillation counting of 59Fe in ferrokinetic studies. PMID- 4212934 TI - An in vitro system for studying the kinetics of interchain disulfide bond formation in immunoglobulin G. PMID- 4212935 TI - An inexpensive methodology for immunization surveys. PMID- 4212936 TI - An investigation of Takahashi's antitubercle phosphatide kaolin agglutination test (KAT) in leprosy. PMID- 4212937 TI - An omega protein from Drosophila melanogaster. PMID- 4212939 TI - An A-V shunt for long-term hyperalimentation in azotaemic patients. PMID- 4212940 TI - Analgesics. 2. Selected 5-substituted 5-(1-phenylethyl)barbituric acids. PMID- 4212941 TI - Analysis of mathematical models of the effect of pH on fermentation processes and their use for calculating optimal fermentation conditions. PMID- 4212942 TI - Antagonism of prostaglandins induced uterine contraction by cyproheptadine hydrochloride. PMID- 4212943 TI - Anti-histone KSAchicken antibody from guinea pig. PMID- 4212944 TI - Antibacterial action of the essential oils of some Australian Myrtaceae with special references to the activity of chromatographic fractions of oil of Eucalyptus citriodora. PMID- 4212945 TI - Antibiotics, antiseptics and tubercle bacilli. PMID- 4212946 TI - Antibody activation of mutant human fructosediphosphate aldolase B in liver extracts of patients with hereditary fructose intolerance. PMID- 4212947 TI - Antibody affinity. VI. Synthesis of bivalent lactosyl haptens and their interaction with anti-lactosyl antibodies. PMID- 4212948 TI - Anticomplementary sera in cutaneous vasculitis. PMID- 4212949 TI - Anticonvulsant effect of diphenylhydantoin relative to plasma levels. A prospective three-year study in ambulant patients with generalized epileptic seizures. PMID- 4212950 TI - Antisera produced to purified extracellular pectolytic enzymes from Sclerotinia fructigena. PMID- 4212952 TI - Application of the continuous maximum principle to fermentation processes. PMID- 4212951 TI - Apparent changes in cancer mortality, 1968. A study of the effects of the introduction of the Eighth Revision International Classification of Diseases. PMID- 4212953 TI - Arterial lesions associated with neurofibromatosis. PMID- 4212954 TI - Arteriovenous fistula for self-treatment of hemophilia. PMID- 4212955 TI - Assay of rifampicin in serum. AB - Two methods for the assay of rifampicin in serum are described. The first is a conventional plate diffusion method, measuring concentrations down to 0.02 mug/ml, and the second a chemical extraction followed by measurement of the inhibition of uptake of (14)C-uridine by Staphylococcus aureus, which estimates in the range of 0.02 to 0.001 mug/ml. The methods were used to measure serum concentrations in man following doses of about 1050 mg and 75 mg rifampicin. PMID- 4212956 TI - Assembly and secretion of immunoglobulin A. PMID- 4212957 TI - Association of type II congenital dyserythropoietic anaemia and von Willebrand's disease. PMID- 4212959 TI - Autoconjugates in Tetrahymena. PMID- 4212960 TI - Autodilution of fungal spore suspensions for viable counting. PMID- 4212961 TI - Automated determination of the IgG and IgM fractions of Rhesus antibodies. PMID- 4212962 TI - Autonomous rDNA molecules containing single copies of the ribosomal RNA genes in the macronucleus of Tetrahymena pyriformis. PMID- 4212963 TI - B cell-derived immunoglobulin on activated mouse T lymphocytes. PMID- 4212964 TI - Background activity in single cells of monkey visual cortex during visual tracking. PMID- 4212965 TI - Bacteremic Pseudomonas pneumonia. PMID- 4212966 TI - Bacteriological findings in perinatal pneumonia. PMID- 4212967 TI - Baker's yeast cytidine deaminase: substrate and inhibitor specificity, and a hypothesis on metabolic and regulatory significance. PMID- 4212968 TI - Beta-glucuronidase in the streptococcal groups B and D. PMID- 4212969 TI - Bilateral recurrent pneumothoraces: a rare complication of miliary tuberculosis. PMID- 4212970 TI - Biochemical changes in the artery wall during genesis and regression of atheromatous lesions. PMID- 4212971 TI - Biphasic stimulo-inhibitory effect of flavonoids on cell proliferation in vitro. PMID- 4212972 TI - Blood group investigations among the gypsy population of Hungary. I. Examination of ABO, MN and Rh blood groups. PMID- 4212973 TI - Blood-group U antigen on Rhnull leukocytes. PMID- 4212974 TI - Bovine adrenal medullary dopamine-beta-hydroxylase: studies on the structure. PMID- 4212975 TI - Bronchial lymphoid tissue. PMID- 4212976 TI - Bursal and postbursal cells in chicken. Occurrence of postbursal cells in bone marrow, thymus and spleen. PMID- 4212977 TI - Cannabis: review of behavioral effects in animals. PMID- 4212978 TI - Capillaria hepatica: granuloma formation to eggs. II. Peripheral immunological responses. PMID- 4212979 TI - Carbonic anhydrase isoenzyme B in erythrocytes of subjects with thyroid disorders. PMID- 4212980 TI - Carbonic anhydrase isoenzymes in nine troops of Kenya baboons, Papio cynocephalus (Linnaeus 1766). PMID- 4212981 TI - Carriage of potentially pathogenic bacteria in the hair. PMID- 4212982 TI - Cause and identification of taste and odour compounds in water. PMID- 4212983 TI - Cell growth cycle and expression of histocompatibility antigens on cultured human lymphoid cells. PMID- 4212984 TI - Changes in metabolism of undamaged sections of myocardium following infarction. PMID- 4212985 TI - Changes in the autoimmunologic reactivity of Wistar rats receiving Freund's complete adjuvant. PMID- 4212987 TI - Characteristics of unit responses in superior colliculus of the Cebus monkey. PMID- 4212986 TI - Characteristics of acid phosphatase in Porcellio laevis latreille (Porcellionidae, Isopoda). PMID- 4212988 TI - Characterization of degradation products of the cell wall released during growth and sporulation of Bacillus megaterium. PMID- 4212990 TI - Chemical, serological and biological properties of a serotype-specific polysaccharide antigen in Leptospira. PMID- 4212989 TI - Chemical and biological basis of adjuvants. PMID- 4212991 TI - Chitinase activity during Drosophila development. PMID- 4212992 TI - Chromosome abnormalities in rabbit preimplantation blastocysts induced by superovulation. PMID- 4212993 TI - Chronic liver disease and hepatitis-B antigen: a prospective study. AB - A long-term follow-up of 45 patients with chronic hepatitis and 41 with cirrhosis is reported. Hepatitis-B antigen (HBAg) was present in 19 (42%) of the chronic hepatitis patients and in 20 (49%) of those with cirrhosis. The clinical course and biochemical and histological findings in the HBAg-positive and the HBAg negative cases were similar, suggesting that HBAg-positive chronic liver disease is not a distinct clinical entity. The presence of antigen and autoantibodies was not found to be mutually exclusive. In HBAg-positive cases antigen tended to persist for months and years. When no irreversible lesions exist disappearance of the antigen may be a sign that the liver disease will resolve. PMID- 4212994 TI - Chronic membranous glomerulonephritis caused by hepatitis B antigen-antibody immune complexes. PMID- 4212995 TI - Cicatricial pemphigoid. Immunofluorescent studies. PMID- 4212997 TI - Clinical effects and uses of hypothalamic releasing and inhibiting factors. PMID- 4212996 TI - Clinical and laboratory studies with tobramycin. PMID- 4212998 TI - Clinical manifestations of coxsackievirus infections in children. PMID- 4212999 TI - Clonazepam in the treatment of epilepsy. PMID- 4213000 TI - Coexistent respiratory allergy and cystic fibrosis. PMID- 4213001 TI - Common parameters in genetic athymia and senescence. PMID- 4213002 TI - Comparative structure, morphogenesis and biological characteristics of the respiratory syncytial (RS) virus and the pneumonia virus of mice (PVM). PMID- 4213003 TI - Comparative study of platelet aggregation in various species. PMID- 4213004 TI - Comparative value of various methods for the preparation of complement-fixing rubella antigen. PMID- 4213005 TI - Comparison between determination of free thyroxine index and effective thyroxine ratio in human serum. AB - Four thyroid function indices were determined in the sera of 181 patients: total thyroxine (T-4), the triiodothyronine resin uptake (T-3 B.C.-index), the free thyroxine (T-4) index, and the effective thyroxine ratio (E.T.R.).A statistically significant correlation between the free T-4 index and E.T.R. could be established though this correlation seemed to be worse than could be expected from the literature. Two sets of correlation coefficients were shown: one obtained with the ordinarily used Pearson or product-moment correlation and one with the Spearman rank correlation. Because the assumptions and requirements for the proper use of the product-moment correlation statistics, such as a normal distribution of both variables, are seldom met, expecially not if a selected number of controls and patients is used for the correlation, it is advisable to use some kind of rank correlation statistics instead.The advantages and disadvantages of the E.T.R. and free T-4 index determination are described. PMID- 4213006 TI - Comparison of different methods for determination of glomerular filtration rate in renal disease. PMID- 4213007 TI - Comparison of the lodoamino acid distribution in thyroglobulins obtained from various animal species. PMID- 4213008 TI - Comparison of transportation media for the culturing of N. gonorrhoeae. PMID- 4213009 TI - Consumer price differentials between generic and brand name prescriptions. PMID- 4213010 TI - Contractile responses and 45Ca movements in monkey ileal smooth muscle. PMID- 4213011 TI - Contribution to the study of the genesis and regulation of characteristic quantities of the quantitative ballistocardiogram. PMID- 4213012 TI - Contributions to the optimal use of human blood. IV. Quantitative analysis of the immunoglobulin isolation. PMID- 4213013 TI - Contributions to the optimal use of human blood. V. A method to increase the yield of anti-D immunoglobulin by processing Cohn's fraction III. PMID- 4213014 TI - Correlated responses of different scute genotypes to long-term selection for increased abdominal bristle number in Drosophila melanogaster. PMID- 4213015 TI - Corynebacterium parvum as a therapeutic antitumor agent in mice. I. Systemic effects from intravenous injection. PMID- 4213016 TI - Corynebacterium parvum as a therapeutic antitumor agent in mice. II. Local injection. PMID- 4213017 TI - Cross-reactivity of Neisseria gonorrhoeae and Neisseria meningitidis and the nature of antigens involved in the bactericidal reaction. PMID- 4213018 TI - Cytophilic properties of IgA to human neutrophils. PMID- 4213019 TI - Cytotoxic effects of imipramine on platelets. PMID- 4213020 TI - CCNU (NSC-79037): preclinical toxicologic evaluation of a single intravenous infusion in dogs and monkeys. PMID- 4213021 TI - Demonstration of acid-base phosphorylation in chromatophores in the presence of a K+ diffusion potential. PMID- 4213022 TI - Descriptive studies of a psychiatric hospital population. PMID- 4213023 TI - Detection and enumeration of salmonella and pseudomonas aeruginosa. PMID- 4213024 TI - Determination of apoceruloplasmin by radioimmunoassay in nutritional copper deficiency, Menkes' kinky hair syndrome, Wilson's disease, and umbilical cord blood. PMID- 4213025 TI - Determination of the light chain type of paraproteins, identification of heavy chain disease. PMID- 4213026 TI - Development and use of meningococcal vaccines. PMID- 4213027 TI - Developmental biochemistry of bovine foetal muscle. I. DNA, RNA, dry matter and total nitrogen. PMID- 4213028 TI - Diabetic acidosis and abnormal chest roentgenogram. PMID- 4213030 TI - Differences in the first progeny of Drosophila melanogaster strains in interspecific competition. PMID- 4213029 TI - Diagnosis of active tuberculosis in a university hospital. AB - Active tuberculosis was diagnosed in 100 patients at Sunnybrook Medical Centre during the five-year period 1968-72. These cases were studied to find out if any delay had taken place in establishing the diagnosis and starting treatment. Delay was found most frequently when patients presented with atypical disease or when microbiological investigations were negative or misinterpreted. However, in nine patients with positive Ziehl-Neelsen smears the diagnosis was delayed more than one week. Usually such delays were caused by a failure to send specimens promptly for examination for acid-fast bacilli. Lack of communication between the laboratory and the clinician was found to be responsible for delays in starting treatment in several patients. It is essential that the clinician in a general hospital be alert to the possibility of tuberculosis and that there be close cooperation between the clinical staff and the diagnostic services. PMID- 4213031 TI - Differential protein clearance in benign and malignant diseases. Application of automated immunonephelometric assay. PMID- 4213032 TI - Differential uptake of human beta-glucuronidase isoenzymes from spleen by deficient fibroblasts. PMID- 4213033 TI - Diphtheria deaths in the United States, 1959-1970. PMID- 4213034 TI - Directories of ambulatory health care facilities. PMID- 4213035 TI - Distribution of human placental lactogen in the last half of normal and complicated pregnancies. PMID- 4213036 TI - Distribution of repetitious sequences in chick nuclear DNA. AB - By an improved method of hydroxylapatite chromatography, the reassociated sequences of chick nuclear DNA were isolated, and their base composition analysed. By increasing the amount of reassociation, the G + C content of the renatured sequences decreased progressively to reach a mean value corresponding to that of the total DNA. In order to study the distribution of the families, or group of families having different amount of reassociation, DNA was fractionated by CsC1 density gradient centrifugation. Fractions having different G + C content were obtained, and their reassociation rates analysed. At high C(o)t value of renaturation (C(o)t=50) the amount of reassociated sequences included in the high or in the low buoyant density DNA fractions was approximately the same, but their G + C content was as expected different. At lower C(o)t values of renaturation (between C(o)t of 0.2 and the C(o)t of 10), the results indicated an heterogeneity of the repeated sequences in the A + T rich DNA fractions, as compared to the G + C rich ones. PMID- 4213038 TI - Distribution of IgA subclasses in sera and bone marrow plasma cells of 21 normal individuals. PMID- 4213039 TI - Disulfide bridges of human immunoglobulins A1 and A2. PMID- 4213040 TI - Double paraprotein aemias (IgMK plus IgGK and IgGK plus BJL). PMID- 4213041 TI - Double-blind crossover study of diphenylhydantoin in angina pectoris. PMID- 4213042 TI - Drosophila rhodopsin: photochemistry, extraction and differences in the norp AP12 phototransduction mutant. PMID- 4213043 TI - Dynamics of nucleic acids and total proteins in the thymus and the bursa of Fabricius of chickens, under the action of cortisol. PMID- 4213044 TI - Early diagnosis of tuberculous meningitis. PMID- 4213046 TI - East Coast fever: quantitative studies of Theileria parva in cattle. PMID- 4213045 TI - East coast fever: 60Co-irradiation of Theileria parva in its tick vector, Rhipicephalus appendiculatus. PMID- 4213047 TI - Editorial: Insulin: rates and routes of delivery. PMID- 4213048 TI - Editorial: Meningococcal infections. PMID- 4213049 TI - Editorial: Prolonged intravenous feeding. PMID- 4213050 TI - Editorial: Synthetic defect in ganglioside metabolism. PMID- 4213051 TI - Editorial: Therapy in genetic disease. PMID- 4213053 TI - Effect of dissolved carbon dioxide on life activity of antibiotic-producing microorganisms. PMID- 4213052 TI - Effect of antibody-complement on multiple vs. single compartment liposomes. Application of a fluorometric assay for following changes in liposomal permeability. PMID- 4213054 TI - Effect of formaldehyde, glutaraldehyde and sucrose on the tissue antigenicity. PMID- 4213055 TI - Effect of hypoglycemic sulfonylureas on hepatic fructose metabolism in the rat. PMID- 4213056 TI - Effect of light and temperature on the bleaching of the yellow mutant Y-1 of Euglena gracilis. PMID- 4213057 TI - Effect of nitroglycerin on the mechanical and metabolic performance of the isolated aerobic and hypoxic rat heart. PMID- 4213058 TI - Effect of nitroglycerine on the quantitative ballistocardiogram. PMID- 4213059 TI - Effect of oxygen tension on the aldolases of Mycobacterium tuberculosis H37Rv. PMID- 4213060 TI - Effect of penicillin irradiation on bacterial growth and penicillin resistance. PMID- 4213061 TI - Effect of thyrocalcitonin on the blood calcium level and degree of adhesion of the hepatocytes. PMID- 4213062 TI - Effect of viscosity on swimming velocity of bacteria. AB - A theory is given for the swimming velocity of a flagellated bacterium and its variation with the viscosity of the surrounding fluid. The theory is shown to agree fairly well with the experimental observations of Schneider and Doetsch on Pseudomonas aeruginosa for viscosities greater than 2 centipoise. However, it fails to account for the decrease of velocity observed when the viscosity decreases from 2 to 1.1 centipoise. PMID- 4213063 TI - Effect of vitamin A and protein-calorie undernutrition on immune responses. PMID- 4213064 TI - Effect of C-reactive protein, PHA, PWM and choline phosphate in 3H-thymidine uptake of leukocytes of leprosy patients and normal individuals. PMID- 4213065 TI - Effect of L8027, a new potent inhibitor of prostaglandin biosynthesis, on the metabolism and response to glucagon of rat adipose tissue. PMID- 4213066 TI - Effects of (-)delta 9-trans-tetrahydrocannabinol on social behavior of squirrel monkey dyads in a water competition situation. PMID- 4213067 TI - Effects of a polychlorinated biphenyl mixture (aroclor 1254) and DDT on biliary thyroxine excretion in rats. PMID- 4213068 TI - Effects of an oral enzyme preparation, Chymoral, upon serum proteins associated with injury (acute phase reactants) in man. PMID- 4213069 TI - Effects of bacterial products on lymphocytes and macrophages: their possible role in natural resistance to listeria infetion in mice. PMID- 4213070 TI - Effects of luteinizing hormone releasing hormone and thyrotrophin releasing hormone on rabbit adipose tissue. PMID- 4213071 TI - Effects of positive pressure ventilation on intrarenal blood flow in infant primates. PMID- 4213072 TI - Effects of proline and hydroxyproline on amino acid levels in Drosophila. PMID- 4213073 TI - Effects of somatostatin on the secretion of thyrotropin and prolactin. PMID- 4213075 TI - Effects of structural heterozygosity on the recovery of autosomal (II-3) translocations from x-irradiated mature and immature oocytes of Drosophila melanogaster. PMID- 4213074 TI - Effects of stearic spin-labels on the photochemical activities of chromatophores from Rhodospirillum rubrum. PMID- 4213076 TI - Effects on the pituitary-thyroid axis and prolactin secretion of single and repetitive oral doses of thyrotropin-releasing hormone (TRH). PMID- 4213077 TI - Electro-oculography. PMID- 4213078 TI - Electron microscopic appearance of dentin after decalcification and recalcification in vitro. PMID- 4213079 TI - Electroradioimmunoassay (ERIA): a new type of double antibody radioimmunoassay based on electroimmunodiffusion. PMID- 4213080 TI - Endoprostheses in the treatment of femoral neck fractures. PMID- 4213081 TI - Enhancement of fat elimination during intravenous feeding. PMID- 4213082 TI - Enhancement of immunogenicity of a BALB-c myeloma protein in BALB-c mice. PMID- 4213083 TI - Environmental pollution, social costs, and health policy in the United States. PMID- 4213084 TI - Epidemiological problems in paediatric intensive therapy and resuscitation unit. PMID- 4213085 TI - Epidemiological study on brucellosis of the Mongolian People's Republic. PMID- 4213086 TI - Epidemiology of selected sarcomas in children. PMID- 4213087 TI - Epizootiology of Minchinia nelsoni in susceptible wild oysters in Virginia, 1959 to 1971. PMID- 4213088 TI - Equilibrium dialysis. PMID- 4213089 TI - Erosions of the skull. PMID- 4213090 TI - Erythroblastosis: the potential for eradication. PMID- 4213091 TI - Essential L-amino acids for hyperalimentation in patients with disordered nitrogen metabolism. PMID- 4213092 TI - Ethylene oxide sterilization kinetics. PMID- 4213093 TI - Ethylenediaminetetraacetate-induced release of RNA and proteins associated with ultrastructural changes in Trichomonas vaginalis. PMID- 4213094 TI - Evaluation and treatment of multiple myeloma and related disorders. PMID- 4213095 TI - Evaluation of a quantitative platelet-collagen adhesiveness test system. PMID- 4213096 TI - Evaluation of the bag--CO2-generating-tablet method for isolation of Neisseria gonorrhoeae. PMID- 4213098 TI - Events surrounding the early development of Euglena chloroplasts: experiments with streptomycin in non-dividing cells. PMID- 4213099 TI - Evidence for heterogeneity of LW antigen revealed in a family study. PMID- 4213097 TI - Events surrounding the early development of Euglena chloroplasts: cellular origins of chloroplast enzymes in euglena. PMID- 4213100 TI - Evidence for inducible, L-malate binding proteins in the membrane of Bacillus subtilis. Identification of presumptive components of the C4-dicarboxylate transport systems. PMID- 4213101 TI - Evidence for C1 on human platelets. PMID- 4213102 TI - Evolution of the marked chromosomes of primates: experimental evidence for centric fusion. PMID- 4213103 TI - Experimental catecholamine-induced chronic cerebral vasospasm. Myonecrosis in vessel wall. PMID- 4213104 TI - Experimental subacute sclerosing panencephalitis in the hamster. Ultrastructure of the chronic disease. PMID- 4213105 TI - Experimental transmission of sarcocysts from cattle to mice. PMID- 4213106 TI - Experimental tuberculosis in lechwe antelope in Zambia. PMID- 4213107 TI - Explanation of a new CHA document: board, CEO, and medical staff relationships. PMID- 4213108 TI - EEG and vigilance during the petit mal attack. PMID- 4213109 TI - Facilitated diffusion of CO2 across albumin solutions. AB - The steady-state CO(2) flux across thin layers of 30 g/100 ml albumin solutions was measured in two different CO(2) partial pressure ranges (boundary PCO(2) values 3 and 8 torr, and 160 and 650 torr, respectively). From the data the apparent diffusion coefficient for CO(2), DCO(2), was calculated. In the high PCO(2) range a value of DCO(2) was found which is to be expected on the basis of diffusion of dissolved CO(2) only. In the low PCO(2) range DCO(2) was about 100% higher than in the high PCO(2) range, when carbonic anhydrase was present and the pH was approximately 7.7. DCO(2) depended on the concentration of carbonic anhydrase. It increased with increasing pH. It is concluded that an additional diffusion of bound CO(2) (facilitated CO(2) diffusion) occurs in the low PCO(2) range and that this transport involves the hydration of CO(2). From the diffusion coefficients in the two PCO(2) ranges the rate of facilitated diffusion was determined. Approximate calculations show that this rate (at pH 84%) diminished by exogenous spermine or spermidine. Arginine and ornithine were both converted efficiently into spermidine, but arginine was the more immediate precursor as shown by isotope competition studies and by the absence of ornithine decarboxylase and the presence of arginine decarboxylase. Exogenous putrescine was not incorporated into spermidine, although it was taken up rapidly and degraded. PMID- 4214103 TI - Assimilation of the atlas and basilar impression: a review of 1,500 skull and cervical spine radiographs. PMID- 4214104 TI - Vitamin E deficiency anemia in Old and New World monkeys. PMID- 4214105 TI - The mode of action of vitamin K. Identification of gamma-carboxyglutamic acid as a component of prothrombin. PMID- 4214107 TI - The morphological and clinical features of membranoproliferative glomerulonephritis in adults. PMID- 4214106 TI - The molecular weight and properties of a neutral metallo-endopeptidase from rabbit kidney brush border. AB - 1. Some properties of a brush-border neutral endopeptidase purified from rabbit kidney were investigated. The peptidase was assayed by its ability to hydrolyse [(125)I]iodoinsulin B chain. 2. The enzyme was found to be homogeneous when studied in the analytical ultracentrifuge and stained as a single glycoprotein band after electrophoresis in polyacrylamide gels. 3. The molecular weight was estimated by gel filtration in columns of Sephadex G-200, by polyacrylamide-gel electrophoresis in the presence of 2-mercapto-ethanol and sodium dodecyl sulphate and by sedimentation equilibrium in the ultra-centrifuge. The estimates fell within the range 87000-96000. The mean from two sedimentation equilibrium experiments was 93000, though this estimate may be slightly inflated because of the carbohydrate component of the enzyme. No evidence of dissociation into smaller subunits was obtained in the presence of thiol, sodium dodecyl sulphate or guanidine hydrochloride. 4. The endopeptidase was maximally active at pH6.0, although in phosphate buffer, which was strongly inhibitory, an optimum above pH8 was observed. 5. The enzyme was not affected by di-isopropyl phosphofluoridate nor by several thiol reagents. It was, however, strongly inhibited by many thiols and by EDTA and other chelating agents. 6. Although activity of the EDTA-treated enzyme could be partially restored by various bivalent metal ions, the optimum concentration for its reactivation by Zn(2+) was lower than that for other ions. This metal was detected in the enzyme preparation by atomic absorption spectrophotometry in an amount equivalent to approximately one atom/mol. 7. The enzyme is the only endopeptidase shown to be located in the kidney brush border and is the first mammalian example of a neutral Zn(2+)- activated endopeptidase to be characterized. PMID- 4214108 TI - Chromosomal abnormalities in a patient with adolescent myelofibrosis. PMID- 4214110 TI - A simple method for the primary isolation of Mycobacterium in a carbon dioxide atmosphere. PMID- 4214109 TI - A comparison of seven strains of Lactobacillus casei var. rhamnosus in relation to their use in the microbiological assay of serum folate. PMID- 4214111 TI - A simple, disposable micro-flow drip regulator. PMID- 4214112 TI - A simplified method for calculating dose-rate distributions from extended volumes containing gamma emitters. PMID- 4214113 TI - Eclampsia during the 16th gestational week. PMID- 4214114 TI - [Stimulation of oogenesis by copulation in female Drosophila melanogaster deprived of their retrocerebral endocrine complex]. PMID- 4214115 TI - [Epimyothelial islands (author's transl)]. PMID- 4214116 TI - Human galactose 1-phosphate uridylyltransferase. Absence of half-reaction activity of galactosemic proteins. PMID- 4214117 TI - Human secretory component. I. Purification of free secretory component from colostrum. PMID- 4214118 TI - An analysis by electron microscopy of intermediates in the replication of linear Tetrahymena mitochondrial DNA. PMID- 4214119 TI - Coronary artery syndromes after sudden propranolol withdrawal. PMID- 4214120 TI - Perinatal calf losses in a beef herd. PMID- 4214121 TI - [Neonatal cholestasis and deficiency of alpha-1-antitrypsin (author's transl)]. PMID- 4214122 TI - The natural habitat of certain primates and the problem in obtaining them for laboratory experimentation. PMID- 4214123 TI - The natural history of diabetes. PMID- 4214124 TI - Advances in research on brucellosis, 1957-1972. PMID- 4214126 TI - Cylinder plate assay for lasalocid sodium. PMID- 4214127 TI - An index for the judgment of optimal mating time in female cynomolgus monkeys (Macaca fascicularis). PMID- 4214125 TI - Freund's adjuvants: relationship of arthritogenicity and adjuvanticity in rats to vehicle composition. PMID- 4214128 TI - Immune competence of hereditarily asplenic mice. PMID- 4214129 TI - Immune response to surface antigens of Staphylococcus aureus and their role in resistance to staphylococcal disease. PMID- 4214130 TI - Hardness of finger nails in well-nourished and malnourished populations. PMID- 4214131 TI - Mating reaction and its daily rhythm in Euplotes crassus. PMID- 4214132 TI - [Changes in blood glucose and insulin in 4 normal subjects after administration of a single dose of glipizide and glibenclamide]. PMID- 4214133 TI - [Changes in late stages of experimental silicosis in rabbits]. PMID- 4214134 TI - [Changes in the properties of Sindbis virus during passage experiments in "Drosophila" (author's transl)]. PMID- 4214135 TI - Meningococcal vulvovaginitis. PMID- 4214136 TI - [Clinical experiences with prodiaban in diabetes mellitus]. PMID- 4214137 TI - [Clinical observations on anesthesia according to Chinese medicine in 1,173 cases]. PMID- 4214138 TI - [Clinical problems of total parenteral feeding in septic states (author's transl)]. PMID- 4214139 TI - [Clinical significance and biochemical consideration of free thyroxine index with special reference to Thyopac index]. PMID- 4214140 TI - [Clinical trials of potassium phenoxymethyl penicillin (apropos of 50 cases)]. PMID- 4214141 TI - [Clinical trials of potassium phenoxymethyl penicillin]. PMID- 4214142 TI - [Clinical trials of potassium phenoxymethyl penicillin]. PMID- 4214143 TI - [Clinicopathological conference no. 19: dizziness, headache, vomiting and obscure vision]. PMID- 4214144 TI - Widening of the paracellular pathway in the kidney tubule by a transtubular osmotic gradient. Passage of graded size non-electrolytes. PMID- 4214145 TI - Techniques for overcoming problems of lipolytic enzymes and lipoxygenases in the preparation of plant organelles. PMID- 4214146 TI - Selenium in human plasma: levels in blood proteins and behavior upon dialysis, acidification, and reduction. PMID- 4214147 TI - Retino-tectal course of optic nerves in cyclopic and synophthalmic zebrafish embryos. PMID- 4214148 TI - Immunochemical characterization of Naja naja siamensis toxin and of a chemically modified toxin. PMID- 4214149 TI - Immunochemical comparisons of vertebrate glutamic acid decarboxylase. PMID- 4214150 TI - Immunochemical method for detection of albumin in human meconium. PMID- 4214151 TI - Immunoglobulins in acute leukemia in children. PMID- 4214152 TI - Immunology and radiology. PMID- 4214153 TI - [Economic efficiency of health systems]. PMID- 4214154 TI - Diagnostic electron microscopy of faeces. II. Acute gastroenteritis associated with reovirus-like particles. AB - Virus particles resembling reoviruses or orbiviruses were found in the faeces of 40 of 73 patients under 6 years of age with acute gastroenteritis and in faeces of only two babies among 31 patients under 6 years admitted to hospital with other diagnoses. In morphology the particles resemble orbiviruses more closely than reoviruses, but differ in appearance from the orbiviruses in having a smooth, circular outline with a well marked continuous rim as seen in negatively stained preparations. They appear not to be serologically related to reovirus types 1, 2, or 3 and may be members of a new group. PMID- 4214155 TI - Prognostic factors in the treatment of acute respiratory insufficiency with long term extracorporeal oxygenation. PMID- 4214156 TI - [Transport of water and sodium by the isolated intestine of the trout, salmo irideus, during adaptation sea-water]. PMID- 4214157 TI - Parenteral nutrition. PMID- 4214158 TI - An interim report on osseous contour reconstruction using alloplastic materials and particulate bone grafting. PMID- 4214160 TI - [Quantitative characteristics of Drosophila melanogaster strains from southern Morocco]. PMID- 4214159 TI - [Identification of Pi system phenotypes and comparison of the methods for the detection of alpha-1-antitrypsin deficiencies]. PMID- 4214161 TI - Mutants of Bacillus subtilis that excrete L-tryptophan. Communication I. Studies of the influence of several mutations in the genome of the revertants to histidine independence on the ability to excrete tryptophan. PMID- 4214163 TI - An investigation into the presence of T strain mycoplasma in the male urethra. PMID- 4214162 TI - [Granular layer of the peripheral chromatin in the interphase nucleus. II. Cytochemical characteristics and properties]. PMID- 4214164 TI - Isoenzymes, multiple enzyme forms, and phylogeny. PMID- 4214165 TI - Micro cell culture method for isolation of Chlamydia trachomatis. AB - Presterilized mictotiter plates (96 wells) with BHK-21 cells on 5-mm cover slips were successfully used for cell culture isolation of trachoma from 15 infected conjunctival scrapings. PMID- 4214166 TI - Microbial activation of prophenoloxidase from immune insect larvae. PMID- 4214167 TI - Microbiologic aspects in patients with leukemia. PMID- 4214168 TI - Microbiological studies on septicemic bullfrogs (Rana catesbeiana). PMID- 4214169 TI - Dislocations of the ankle without fracture. PMID- 4214170 TI - Microcephalic dwarfism in sisters. PMID- 4214171 TI - Photochemical activity and components of membrane preparations from blue-green algae. II. Low-temperature photooxidation of cytochrome b559. PMID- 4214172 TI - Glucocorticoids and thyrotropin releasing hormone (TRH) secretion. PMID- 4214173 TI - [Blood sugar, serum insulin, nonesterified fatty acids and somatotropin in daily profile in adult diabetics under monotherapy with various sulfonylureas]. PMID- 4214174 TI - The odontogenic keratocyst--an approach to treatment. PMID- 4214175 TI - Use of single radial immunodiffusion test for serological studies in volunteers inoculated with live attenuated influenza virus. AB - Pre- and post-vaccination serum samples from 278 volunteers, who were given live influenza vaccines, were tested by haemagglutination inhibition (HI) and single radial immunodiffusion tests(SRDT) for antibody to influenza A/Hong Kong/1/68 (H3N2) virus envelope antigens. Those with high antibody titres detected in both tests were less frequently infected, and 85% of the 159 infected showed rises by HI and 70% by SRDT. Similarly, 69 pairs were tested for antibody to Hong Kong (N2) neuraminidase by neuraminidase inhibition test (NI) and by SRD tests. Those with high titres in both tests resisted infection and those who were infected showed a rise in antibody detected both by NI and SRD tests. In general, SRDT was less sensitive than HI and NI in detecting antibody and antibody rises, but in some volunteers it did detect antibody rises which were not detected by conventional tests. Because of its simplicity and speed it appeared to be of use in evaluating such vaccines. PMID- 4214176 TI - Neurofibromatosis and congenital heart disease. PMID- 4214177 TI - Neurofibromatosis with renovascular hypertension. A case report. PMID- 4214178 TI - [Hypogammaglobulinemia in patients with the syndrome of absorption disorders]. PMID- 4214179 TI - Biological deactivation of Rg seed dressing in soil. PMID- 4214180 TI - Biological properties of surface components of Listeria monocytogenes (Ei factor). PMID- 4214181 TI - Biologically active components of the cells of gram-positive bacteria. PMID- 4214182 TI - Haemoglobin G St. Jose in an Italian family. PMID- 4214183 TI - Thyroglossal cysts and fistulae. PMID- 4214184 TI - Thyroid tumors. PMID- 4214185 TI - Radioimmunoassay of thyrotropin-releasing hormone (TRH) in human plasma and urine. PMID- 4214186 TI - [Serological prevalence of Chagas' disease in 5 municipalities of the southern region of Rio Grande do Sul]. PMID- 4214187 TI - Histological studies on the follicles with special reference to their atresia in Egyptian buffaloes. PMID- 4214188 TI - [Serological studies on Paragonimius uterobilateralis and other trematodal antigens with sera from paragonimiasis-patients from Nigeria (author's transl)]. PMID- 4214189 TI - A biometric study of three strains of Tetrahymena pyriformis (Ciliatea: Hymenostomatida). PMID- 4214190 TI - [A comparative study of the polysaccharides produced by the fungi "Ceratocystis stenoceras" and "Sporothrix schenckii". Chemical nature and immunological properties (author's transl)]. PMID- 4214191 TI - "Incomplete subserotypes" and the cryptic axial filament antigen of Leptospira. PMID- 4214192 TI - Seasonal prevalence of avian hematozoa in passeriform birds of Atlantic Canada. PMID- 4214193 TI - Pulmonary abnormalities in sepsis. PMID- 4214194 TI - Pulmonary emphysema and alpha1-antitrypsin deficiency. PMID- 4214195 TI - Pulmonary host defenses in rabbits after immunization with Pseudomonas antigens: the interaction of bacteria, antibodies, macrophages, and lymphocytes. PMID- 4214196 TI - [Endonasal beta-therapy of chronic rhinosinusopathy]. PMID- 4214197 TI - Preponderance of gram-positive infections during parenteral alimentation. PMID- 4214198 TI - A spondyloepiphyseal dysplasia with peripheral dysostosis. PMID- 4214199 TI - Pyelonephritis transferred by parabiosis. PMID- 4214200 TI - Prolonged extracorporeal cardiopulmonary support in man. PMID- 4214201 TI - Lesions in the cells of proximal convoluted tubules in rat kidney induced by amanitin-albumin conjugate. PMID- 4214202 TI - Response patterns of primary vestibular neurons to thermal and rotational stimuli. PMID- 4214203 TI - [Demonstration of proteases with elastolytic activity in extracts of human and animal aortas]. PMID- 4214204 TI - [Demonstration of virions of the Baculo-virus type in the genital system of the coleopteron, Oryctes rhinoceros L]. PMID- 4214205 TI - Oligonucleotides and the quaternary structure of gene-5 protein from filamentous bacteriophage. PMID- 4214206 TI - [Paronychias and onychias caused by Pseudomonas pyocyanea]. PMID- 4214207 TI - Histopathology and ultrastructure of cartilage in the chondrodystrophies. PMID- 4214208 TI - Isotope techniques for studying the dynamics of nitrogen metabolism in ruminants. PMID- 4214209 TI - Postoperative oral and intravenous nutrition. AB - Oral and intravenous high calorie-amino acid nutritional therapy postoperatively resulted in significant weight gain, improved colonic wound healing and maintenance of normal intravascular albumin levels. Provision of caloric needs without amino acids minimized weight loss postoperatively. However, infusion of hypertonic dextrose solutions resulted in severe generalized hepatic fatty infiltration and marked hypoalbuminemia. Protein and calorie deprivation by administration of 5% dextrose and water resulted in the greatest postoperative weight loss, reduced intravascular albumin levels and decreased colonic anastomotic strength. Comparison of oral and intravenous diet administration demonstrated that hypertonic dextrose infusion was markedly deleterious to hepatic morphology and serum protein metabolism in normal rats. Further clinical investigation appears indicated in previously well-nourished patients undergoing extensive surgery who will not be able to ingest adequate nutrients in the postoperative period. PMID- 4214210 TI - Cricopharyngeal achalasia. PMID- 4214211 TI - Pathophysiology of vitamin E deficiency in monkeys. PMID- 4214212 TI - Genioplasty with reference to resorption and the hinge sliding osteotomy. PMID- 4214213 TI - Restoration of deficient edentulous ridges by bone grafting and the use of subperiosteal metal implants. PMID- 4214214 TI - The order of replication of chromosomal markers in Pseudomonas aeruginosa strain 1. I. Marker frequency analysis by transduction. PMID- 4214216 TI - Editorial: Malnutrition in the hospital. PMID- 4214215 TI - Photoreactivation, photoproduct formation, and deoxyribonucleic acid state in ultraviolet-irradiated sporulating cultures of Bacillus cereus. AB - Photoreactivation of ultraviolet-irradiated Bacillus cereus T declined markedly during the development of stage IV forespores. During ultraviolet irradiation of a culture containing early and late stage IV forespores, both vegetative- and spore-type photoproducts were formed. The formation of vegetative-type photoproducts (mainly thymine dimers) decreased to nearly half during late stage IV, remaining constant until lysis of the mother cells began, when it fell to zero. Spore-type photoproducts were first observed during late stage IV and increased with the increase in numbers of late stage IV forespores. The occurrence of spore-type photoproducts preceded the development of refractile forespores by about 1 h. At stage III the nuclear material occupied a central position, and the ribosomes were at the periphery of the forespore protoplast. During stage IV the deoxyribonucleic acid (DNA) occurred in a peripheral position, and bundles of fibers ("transition" DNA) could be seen. By stage V, all of the DNA appeared to be of the spore type and was peripheral, and the forespore protoplast center was packed with ribosomes. Forespore stages II, III, and IV were classified by light and electron microscopy. The curve for electron microscope classifications preceded that for light microscope classifications by approximately one stage. The formation of spore-type photoproducts preceded differentiation of DNA by about 1 h, the latter coinciding with the development of refractility. Spore-type photoproducts have been associated with DNA in the A state, and the progressive change of the forespore DNA into this state is discussed in relation to the spore differentiation process. PMID- 4214217 TI - Editorial: Sarcoidosis and tuberculosis. PMID- 4214218 TI - Editorial: The management of diabetic acidosis. PMID- 4214219 TI - Editorial: The threat of gastro-intestinal infections in Lebanon. PMID- 4214220 TI - Editorial: There is more to health than just paying bills. PMID- 4214221 TI - Conformational properties of some viral DNAs. PMID- 4214222 TI - [Gonorrheal chorioamnionitis]. PMID- 4214223 TI - Factors in human serum promoting phagocytosis of Pseudomonas aeruginosa. I. Interaction of opsonins with the bacterium. PMID- 4214224 TI - Factors in human serum promoting phagocytosis of Pseudomonas aeruginosa. II. Interaction of opsonins with the phagocytic cell. PMID- 4214225 TI - Factors in the mechanism of persistence of viral infections. PMID- 4214226 TI - [Report of autointoxication experiment with Bacillus cereus (author's transl)]. PMID- 4214227 TI - [Importance of the thyrotropin-releasing hormone (TRH) stimulation test in latent thyroid functional disorders]. PMID- 4214228 TI - Formosan monkey (Macaca cyclopis): present situation in Taiwan and its reproductive biology. PMID- 4214229 TI - Glucose uptake and phosphorylation in Pseudomonas fluorescens. AB - Pseudomonas fluorescens ATCC 13525 and a particulate glucose oxidase (d glucose:oxygen oxidoreductase, EC 1.1.3.4) mutant of this organism, gox-7, were examined to determine if glucose oxidation via particulate glucose oxidase is a required first step for glucose uptake. Initial [(14)C]glucose-uptake rates in parent and gox-7 cells were qualitatively similar. Initial [(14)C]glucose-uptake product analysis revealed that glucose was accumulated via active transport and was rapidly metabolized to glucose-6-phosphate and gluconate-6-phosphate in both parent and gox-7 cells. Cell extracts contained soluble adenosine 5'-triphosphate specific kinase activity for phosphorylation of glucose. Glucose uptake was induced by glucose and not gluconate, thus, establishing independent regulation of glucose transport and glucose catabolism in p. fluorescens. The results prove that glucose oxidase was not an obligatory reaction for glucose carbon permeation in P. fluorescens. A general unifying scheme for glucose utilization in the aerobic fluorescent pseudomonads is suggested for the purpose of clarifying glucose uptake in these bacteria. PMID- 4214230 TI - Glycosidases with unusual specificities. IV. A hydrolase that splits p nitrophenyl-2-deoxy-2-glycylamido-beta-D-glucopyranoside: properties of the purified enzyme. PMID- 4214231 TI - Disposition of SCH 10595 in animals and man. PMID- 4214232 TI - [Xerostomia and asalia due to psychopharmacologic therapy and their treatment with TPMP (trithioparamethoxyphenylpropen)]. PMID- 4214233 TI - Aminosugar-containing low molecular weight acidic compounds present in urine of normal children and of patients affected by mucopolysaccharidosis type II, 3 or IV. PMID- 4214234 TI - Amniotic fluid alpha-fetoprotein in the antenatal diagnosis of neural tube defects. PMID- 4214235 TI - The outer cell-wall membrane of Pseudomonas aeruginosa. PMID- 4214237 TI - Improved meals for geriatric patients. PMID- 4214236 TI - Improved isolation and differentiation of enterococci in cheese. AB - Further documentation of an enterococcus selective differential (ESD) medium was obtained in isolations from eight different cheeses. An improved differentiation of tetrazolium salt (2, 3, 5-triphenyl tetrazolium hydrochloride [TTC])-reducing strains of Streptococcus faecalis from TTC-nonreducing or TTC-faintly-reducing Streptococcus faecium was attained. The sensitivity of the medium was evaluated in comparison with that of KF streptococcal, Pfizer selective enterococcus (PSE), the medium of Reinbold, Swern, and Hussong (RSH), and the medium of Saraswat, Clark, and Reinbold (SCR). Selective counts, rate of colony formation, and ease of isolation and differentiation of colonies were examined. The specificity of the medium was also investigated. ESD supported the fastest rate of growth and the maximum size of colonies; counts in this medium were in most cases possible with 17 h of incubation, whereas the other media required 24 to 48 h. A presumptive identification of 1,077 isolates by four biochemical tests disclosed that SCR, RSH, and ESD selected high, comparable percentages of strains that approximated most closely the typical description of enterococci (66, 60.1, and 58%, respectively). Low percentages (21.1 and 30.7%) were yielded by KF and PSE. The utility of ESD for a rapid, presumptive identification of enterococci was confirmed by serological and biochemical testing of color TTC-differentiated colonies isolated from 18 cheeses. PMID- 4214238 TI - Antiovulatory activity of the thyrotropin releasing hormone in the rat. PMID- 4214239 TI - Follow-up study of 103 American soldiers who sustained a brain wound in Vietnam. PMID- 4214240 TI - Non-oxygen induced retinitis proliferans and retinal detachment in full-term infants. PMID- 4214241 TI - The oxygenase activity of ribulose-1,5-bisphosphate carboxylase from Rhodospirillum rubrum. PMID- 4214242 TI - [Deep Candida infections in children. A clinicopathological study of 25 cases]. PMID- 4214243 TI - [Preparation of glycosidases from germinated seeds of Canavalia ensiformis]. PMID- 4214244 TI - [Comparative analysis of the intraspecific nuclear graft in Bufo bufo L., Bufo calamita Laur., Bufo viridis Laur. (anourous amphibia)]. PMID- 4214245 TI - [Comparative study of the retention capacity of alimentary learning in 2 strains of consanguineous mice]. PMID- 4214246 TI - [Comparative ultrastructural study of dyskinetoplastic strains of Trypanosoma gambiense and Trypanosoma evansi]. PMID- 4214247 TI - [Comparison between the activity of 2 amino-glycoside antibiotics, tobramycin and gentamicin on gram negative bacteria in vitro]. PMID- 4214248 TI - [Comparison of normal responses of the auditory nerve in the guinea-pig, monkey and man]. PMID- 4214249 TI - Nonspecific urethritis. PMID- 4214250 TI - [Stapedectomy in otosclerosis. A preliminary report]. PMID- 4214251 TI - Stempellia milleri sp. n. (Microsporida: Nosematidae) in the mosquito Culex pipiens quinquefasciatus Say. PMID- 4214252 TI - [ A phenomenon of sterility of non-mendelian origin in Drosophila melanogaster: absence of contact contagion factors]. PMID- 4214253 TI - [Morphological changes in the temporomandibular joint in models of saggittal bite anomalies in monkeys]. PMID- 4214254 TI - Phosphorylase, 1,4-1,6-transglucosidase and UDPG-synthetase in lenses of different species. PMID- 4214255 TI - The phospholipid-dependence of uridine diphosphate glucuronyltransferase. Effect of protein deficiency on the phospholipid composition and enzyme activity of rat liver microsomal fraction. AB - After force-feeding a protein-free diet to male rats for 5-7 days a substantial (2.4-fold) increase in the specific activity of the liver microsomal enzyme UDP glucuronyltransferase (EC 2.4.1.17) was observed. A similar activation of the enzyme occurred when rats were fed on a low-protein (5%, w/w, casein) diet for 60 days. Although both the short- and long-term protein-deficient diets decreased the contents of microsomal protein and phospholipid in liver tissue they did not significantly alter the ratio of these major membrane components. Protein deficiency profoundly altered the phospholipid composition of microsomal membranes. The most striking difference in microsomal phospholipid composition between control and protein-deficient rats was their content of lysophosphatides. Whereas microsomal membranes from protein-deficient rats contained significant proportions of lysophosphatidylcholine and lysophosphatidylethanolamine very little or no lysophosphatides were detected in control preparations. Pretreatment of microsomal fractions from normal rats with phospholipase A markedly increased their UDP-glucuronyltransferase activity as did their pretreatment with lysophosphatidylcholine. It is concluded that the quantities of lysophosphatides present in microsomal membranes from protein-deficient rats were sufficient to have caused the increased UDP-glucuronyltransferase activities of these preparations. Evidence is presented suggesting that these changes in microsomal phospholipid composition and UDP-glucuronyltransferase activity caused by protein deficiency reflect changes that occur in vivo. The possible physiological significance of these findings is discussed. PMID- 4214256 TI - Scrapie. PMID- 4214257 TI - The pigment complement of the photosynthetic reaction center isolated from Rhodospirillum rubrum. PMID- 4214258 TI - Norepinephrine and dopamine in the limbic system of the rat. PMID- 4214259 TI - [Complications of duodenal diverticula. Apropos of 4 cases]. PMID- 4214260 TI - [Complications of gonorrhea]. PMID- 4214261 TI - [A spontaneous nephropathy of Wistar-type rats. The light and electron micoscopic changes of the glomerula (author's transl)]. PMID- 4214262 TI - TRH potentiates behavioural changes following increased brain 5-hydroxytryptamine accumulation in rats. PMID- 4214263 TI - EEG prediction of brain metastases. A controlled study with neuropathological confirmation. AB - A retrospective study comparing the EEG findings of two groups of patients with primary systemic malignant disease (mainly bronchial carcinoma) was carried out. One group of 13 patients (20 EEGs) had proven supratentorial cerebral metastases at necropsy, some also subtentorial, and the other group of 10 patients (15 EEGs) had no cerebral involvement at necropsy. The latter group was studied to assess the possible confusing effects in the EEG of metabolic derangements and other factors which would interfere with accurate prediction of the presence of metastases. The EEGs were masked and assessed independently by two raters using a special proforma. They found that recordings from patients with cerebral metastases had persistent focal delta activity, intermittent focal or local delta activity, persistent or intermittent lateralized delta activity, monorhythmic frontal delta activity in the alert patient, as well as a higher frequency of post-central background rhythms. These factors predicted the presence of cerebral metastases (when they were 2 cm in diameter or larger) in 12 out of the 13 patients (four of these without localized neurological disorder), the EEGs being taken on average eight weeks before death. It is concluded that the EEG is valuable in the investigation of these patients. PMID- 4214264 TI - The present situation of Japanese monkeys in their natural habitat. PMID- 4214265 TI - The preservation of substance and immunological activity of intra venously injected human IgG in the mouse liver. (Comparative studies on various tissue preparation and fixation methods). PMID- 4214266 TI - The primate foveal local electroretinogram: an indicator of photoreceptor activity. PMID- 4214267 TI - The problems of correction of asymmetric mandibular prognathism. PMID- 4214268 TI - The proteolytic enzymes of the K-1 strain of Steptomyces griseus obtained from a commerical preparation (pronase). Stabilization of the trypsin component by calcium and guanidine. PMID- 4214269 TI - Streptococcus mutans endocarditis. Confusion with enterococcal endocarditis by routine laboratory testing. PMID- 4214270 TI - A population screening for fetal sulfoglycoprotein antigen in gastric juice. PMID- 4214271 TI - Oblique sliding osteotomy of the mandibular rami in 55 patients with mandibular prognathism. PMID- 4214272 TI - A sequence analysis of 5 S rRNA from the blue-green alga Oscillatoria tenuis and a comparison of blue-green alga 5 S rRNA with those of bacterial and eukaryotic origin. PMID- 4214273 TI - [Frequency of infection and spectrum of type of organisms in neurosurgical cases nursed in intensive care unit (author's transl)]. PMID- 4214274 TI - [Star folds in retinal detachment. A clinical electron-microscopic correlation (author's transl)]. PMID- 4214275 TI - Super-active forms of placental lactogen and prolactin. PMID- 4214276 TI - Tumor-bound immunoglobulins: their possible role in circumventing antitumor immunity. PMID- 4214277 TI - [Characteristics of excitation of visual cortical cells of 5-week-old kittens reared with or without visual experience]. PMID- 4214278 TI - [Characteristics of Drosophila ribosomes and ribosomal RNA]. PMID- 4214279 TI - Interaction of chemical carcinogens with plasma membranes: the effect of dimethylaminoazobenzene on erythrocyte osmotic fragility. PMID- 4214280 TI - Natural infection of cynomolgus monkeys with measles virus. PMID- 4214281 TI - Natural resistance to infection in the neonatal sheep: comparison of the ability of colostrum-deprived, normally-suckled and passively-immunized lambs to localize Erysipelothrix rhusiopathiae. PMID- 4214282 TI - An oral surgeon's experience with the intraosseous blade implant. PMID- 4214283 TI - [Intraluminal diverticulum of the duodenum]. PMID- 4214285 TI - [Therapeutic efficacy of some antifungal preparations]. PMID- 4214284 TI - [Therapeutic activity of a glibenclamide-phenformin association in maturity-onset diabetes]. PMID- 4214286 TI - [Therapy of sound-perception deafness using cinnarizine (Stutgeron forte)]. PMID- 4214287 TI - [Ultrastructure of some bacteriophages of Agrobacterium tumefaciens]. PMID- 4214288 TI - [Titration of anti-L-asparaginase and L-asparaginase by passive hemagglutination using the L-asparaginase coated sheep red cell with glutaraldehyde (author's transl)]. PMID- 4214289 TI - Separation, isolation, and immunological studies of the structural proteins of Venezuelan equine encephalomyelitis virus. AB - Three viral proteins were separated from the TC-83 strain of Venezuelan equine encephalomyelitis virus by discontinuous polyacrylamide gel electrophoresis after disruption with sodium dodecyl sulfate and beta-2-mercaptoethanol. These proteins were inoculated into rabbits and the resultant antisera were tested for immunological activity by gel precipitation, plaque reduction neutralization, hemagglutination inhibition (HI), complement fixation, fluorescence microscopy, and mouse protection studies. All proteins were capable of stimulating precipitating antibody in rabbits, but the largest protein (VP 1), which is contained in the envelope, stimulated the production of detectable neutralizing and HI antibody against the intact virion. The other two proteins yielded little or no neutralizing or HI antibody. PMID- 4214290 TI - Laboratory animals: principles, practice and prospects. PMID- 4214291 TI - [Intravenous nitrogenic hyperalimentation in surgery (author's transl)]. PMID- 4214292 TI - Hyperbaric oxygen in total rehabilitation of patients with mandibular osteoradionecrosis. PMID- 4214293 TI - Hypercalcaemia and mineralisation of non-osseous tissues in horses due to vitamin D toxicity. PMID- 4214294 TI - The reaction of anthramycin with DNA. II. Studies of kinetics and mechanism. PMID- 4214295 TI - [Increase of erythrocyte superoxide dismutase activity in trisomy for chromosome 21]. PMID- 4214296 TI - Comprehensive outpatient respiratory care: a program conducted in a suburban private practice. PMID- 4214297 TI - The relationship between platelets and bacteria. PMID- 4214298 TI - [Current knowledge in the endocrinology of reproduction of domestic animals. IV. Neuro-endocrine integration]. PMID- 4214299 TI - [Current status of prevention of endogenous affective diseases using lithium]. PMID- 4214300 TI - Fluorescent products and lysosomal components in aging Drosophila melanogaster. PMID- 4214301 TI - Suppressor-sensitive mutants and genetic map of Bacillus subtilis bacteriophage phi 29. PMID- 4214302 TI - Hydergine-thioridazine combination in the treatment of psychopathological states in old age. PMID- 4214303 TI - Synergistic necrotizing myositis complicating vascular injury. PMID- 4214304 TI - Viruria in man, an update. PMID- 4214305 TI - Arterial developmental anomalies of one hemisphere with inter- and intrahemispheric steal effects in neurofibromatosis (Recklinghausen's disease). PMID- 4214306 TI - Fimbrial haemagglutination by Neisseria gonorrhoeae. PMID- 4214307 TI - Distribution of ABO and Rh(D) phenotypes in Uganda. PMID- 4214308 TI - Gastric emptying and secretion of bile acids, cholesterol, and pancreatic enzymes during digestion. Duodenal perfusion studies in healthy subjects. PMID- 4214309 TI - Restriction by H-2 gene complex of transfer of cell-mediated immunity to Listeria monocytogenes. PMID- 4214310 TI - Experiences in quarantine of imported monkeys. PMID- 4214311 TI - Experimental bacteremia due to Pseudomonas in agranulocytic animals. PMID- 4214312 TI - Experimental burn wound sepsis--evaluation of enzymatic debridement. PMID- 4214313 TI - Experimental cerebral hemodynamics. Vasomotor tone, critical closing pressure, and vascular bed resistance. PMID- 4214314 TI - Experimental choroidal detachments. PMID- 4214315 TI - Experimental infection of dogs and monkeys with two rabies serogroup viruses, Lagos bat and Mokola (IbAn 27377). Gross pathologic and histopathologic changes. PMID- 4214316 TI - Experimental parathyroiditis in the rat by passive immunisation. PMID- 4214317 TI - Experimental pneumonia due to Pseudomonas in dogs: controlled trial of granulocyte transfusion therapy. PMID- 4214318 TI - Experimental primates in Asia. Usefulness of non-human primates: remarks from the user's viewpoint. PMID- 4214319 TI - Experimental retinal detachment in owl monkeys. Effect of intravitreal hyaluronidase injection and embolization of the choroidal and retinal circulation. PMID- 4214321 TI - Veterinary nuclear medicine. PMID- 4214320 TI - Experimental toxoplasmosis in the stumptailed macaque (M. arctoides). PMID- 4214322 TI - Exocrine pancreatic function tests in patas monkeys (Erythrocebus patas). PMID- 4214323 TI - Hyperlactataemia during intravenous feeding in childhood. PMID- 4214324 TI - [Pharmacology and clinical application of a muscle relaxant, han chi sung]. PMID- 4214325 TI - Intermediates in the replication of the mitochondrial DNA of Tetrahymena pyriformis. PMID- 4214326 TI - Determinants of reversible asynergy. Effect of pathologic Q waves, coronary collaterals, and anatomic location. PMID- 4214327 TI - Determination of the volume and surface area of Tetrahymena pyriformis, and their relationship to endocytosis. PMID- 4214328 TI - External uterine palpation to identify stages of pregnancy in the marmoset, Saguinus fuscicollis SSP. PMID- 4214329 TI - Anaerobic utilization of uric acid by some group D streptococci. PMID- 4214330 TI - Sideroblastic anaemia presenting as monoarticular arthritis. PMID- 4214331 TI - Arthrography of the knee after meniscectomy. PMID- 4214332 TI - Filaroides cebus (Gebauer 1933)-parasitism and respiratory infections in Cebus apella. PMID- 4214333 TI - The role of immunoglobulin in the neutralization of trachoma infectivity. PMID- 4214334 TI - The role of Zn(II) in transcription by T7 RNA polymerase. PMID- 4214335 TI - The roles of various biochemical effects produced by 5-fluorouracil in early growth inhibition of Bacillus cereus. PMID- 4214336 TI - [Neurological aspects of so-called late epilepsy (author's transl)]. PMID- 4214337 TI - Rh prophylactic treatment during pregnancy. An attempt to select for treatment those at possible risk. PMID- 4214338 TI - Arthropod-borne viruses in Australia and their relation to infection and disease. PMID- 4214339 TI - [Neurosurgical treatment of epilepsy]. PMID- 4214340 TI - [Neurotoxicity of chinoform and its distribution and metabolism]. PMID- 4214341 TI - Occurrence and localization of brain phenolsulphotransferase. PMID- 4214342 TI - Recurrent urinary tract infection. With persistent Wolffian duct masquerading as duplicated urethra. PMID- 4214343 TI - Gonorrhea in children and adolescents: a current review. PMID- 4214345 TI - Inverse relation between serum IgG concentration and glucose and xylose absorption in Zambian African adults. AB - In three separate investigations in Zambian African adults in Lusaka an inverse association has been shown between serum IgG concentration and either glucose absorption rate from the jejunum (from a 200-mM solution) or xylose absorption (from a 25-g oral load). In developing areas of the world, where serum IgG concentrations are often high, this finding may have widespread nutritional implications. PMID- 4214344 TI - Tumors of neurons and their precursors. PMID- 4214346 TI - Report on the differentiation of vascular wall smooth muscle cells with the aid of immunofluorescence. PMID- 4214347 TI - Importation of cynomolgus monkeys: a review. PMID- 4214348 TI - Hyperthermia as a teratogenic agent. AB - The common cotton-eared marmoset, a nonhuman primate with a narrow zone of thermoneutrality, was used in an experiment to assess the effects of hyperthermia as a teratogenic agent. Mild heat stress conditions were used. The results of this preliminary study justify further investigation of the effect of hyperthermia on the primate embryo during morphogenesis. PMID- 4214349 TI - A virus-induced component of plant sap needed when aphids acquire potato virus Y from purified preparations. PMID- 4214351 TI - [Fabry's disease (angiokeratoma corporis diffusum)]. PMID- 4214350 TI - Observations on non-pigmented haemosporidia of Brazilian lizards, including a new species of Saurocytozoon in Mabuya mabouya (Scincidae). PMID- 4214352 TI - [Does "altruism" exist in lower simians?]. PMID- 4214353 TI - Gross conformation of human secretory immunoglobulin A and its component parts. PMID- 4214354 TI - Roles of conglutinin, complement, and antibody size in the card agglutination test for bovine anaplasmosis. PMID- 4214355 TI - Polysaccharide that may serve as a carbon and energy storage compound for sporulation in Bacillus cereus. AB - An intracellular, glucose-containing polysaccharide accumulates in Bacillus cereus early in sporulation and is degraded at the time of spore maturation. This pattern of accumulation and degradation occurred when growth was limited by glucose or a component of yeast extract. These data suggest that the polysaccharide may be serving as a carbon and energy storage compound for sporulation. A somewhat similar pattern of accumulation and degradation of poly beta-hydroxybutyric acid (PHB) was shown earlier by Kominek and Halvorson (1965) to occur in Bacillus cereus. When cells were grown in a medium buffered strongly at pH 7.4, however, very little accumulation of PHB occurred. We have found that polysaccharide accumulates in cells grown in both the strong and weakly buffered media. Perhaps polysaccharide is the major carbon and energy storage compound when cells are grown under conditions preventing significant accumulation of PHB. The lack of polysaccharide accumulation during the exponential phase of growth may be an indication that the needed biosynthetic enzymes are controlled by catabolite repression during growth. The polysaccharide was purified and found to consist of glucose. The iodine absorption spectrum suggests a degree of branching between that of glycogen and amylopectin. PMID- 4214356 TI - A viscometric study of sputum glycoprotein aggregation. PMID- 4214357 TI - Lipase activity of detergent-resistant phospholipase A in Escherichia coli. PMID- 4214358 TI - A case of extradural meningioma treated successfully with high energy electron. A brief review of literature. PMID- 4214359 TI - The secretion of A,B,H and Lewis blood group substances in the gastric juice and saliva of chacma baboons (Papio ursinus, Kerr) and vervet monkeys (Cercopithecus pygerythrus, Cuvier. PMID- 4214360 TI - [Griseofulvous pills in the treatment of tinea capitis]. PMID- 4214361 TI - Transfer factor therapy in a patient with chronic vaginal candidiasis. PMID- 4214363 TI - [Possibilities and limits of hemodialysis in the hospital and at home]. PMID- 4214362 TI - Transfer of photosynthetically produced carbohydrate from endosymbiotic Chlorellae to Paramecium bursaria. PMID- 4214364 TI - [Possible role of cholesterol in cellular membranes]. PMID- 4214365 TI - [Physical and biological parameters of interest for evaluating the possible use of pi-mesons, neutrons and charged particles in radiotherapy (author's transl)]. PMID- 4214366 TI - Tyrosinase in the skin of albino hamsters and mice. PMID- 4214367 TI - [Physiopathology of magnesium]. PMID- 4214369 TI - Parasitic protozoa of the blood of rodents: a revision of Plasmodium berghei. PMID- 4214368 TI - [Persistance of morphologic differences between thymodependent and thymo independant lymphocytes in the mouse after selective antigenic sollicitation of one or the other population]. PMID- 4214370 TI - Transitional cell carcinoma of the bladder associated with cyclophosphamide. PMID- 4214371 TI - Glossitis of military working dogs in Vietnam: experimental production of tongue lesions. PMID- 4214372 TI - [Sensitivity tests of 260 bacterial strains isolated from urinary tract infections]. PMID- 4214373 TI - Adhesive tape: potential source of nosocomial bacteria. AB - During a 7-day period, a variety of bacteria, including opportunistic ones, were recovered from 23 rolls of adhesive tape being used in a 16-bed intensive care unit. All rolls of tape were sterile when received from the manufacturer. Mixed flora was recovered from a total of 15 rolls, whereas eight rolls yielded pure cultures. Organisms recovered included Staphylococcus aureus, Pseudomonas aeruginosa, and various species of Enterobacteriaceae. Although no illness or infection arising directly from contaminated adhesive tape has been documented, we feel that a potential source of infection has been identified. Most important is the fact that such tape may contaminate the hands of personnel who handle it. Also, the adhesive tape may directly contaminate a patient since it is widely used to secure artificial airways and various drainage tubes which results in the tape coming into close contact with the mucous membranes lining the patient's respiratory and urogenital tracts. PMID- 4214374 TI - Translation of virus mRNA: synthesis of bacteriophage PP7 proteins in cell-free extracts from Pseudomonas aeruginosa. PMID- 4214375 TI - Autosomal dominant transmission of isolated growth hormone deficiency in iris dental dysplasia (Rieger's syndrome). PMID- 4214376 TI - Transoral surgical removal of a sialolith in the submandibular gland. PMID- 4214377 TI - Transport capacity of median eminence: in vitro uptake of 3H-LRF. PMID- 4214378 TI - Transport of material between brain extracellular fluid, brain cells and blood. PMID- 4214379 TI - Assessment of the carcinogenicity and mutagenicity of chemicals. Report of a WHO Scientific Group. PMID- 4214380 TI - A test system for the biological safety cabinet. AB - A simple, cheap and readily available test system for biological safety cabinets is described. It depends on the containment of an aerosol of Bacillus subtilis spores generated in a BIRD micronebulizer and the measurement of air flows with an anemometer. The system was set up to survey new equipment but equally valuable results have been obtained from tests during use. New units were often badly installed and used equipment was poorly maintained. It is suggested that any department which has a need for a biological safety cabinet must be in a position to test its function. PMID- 4214382 TI - Resistance of Pseudomonas aeruginosa to aminoglycoside antibiotics. PMID- 4214381 TI - Resistance of bacterial protein synthesis to double-stranded RNA. PMID- 4214383 TI - Resistance of Staphylococcus aureus to penicillins and cephalosporins: reversal of intrinsic resistance with some chelating agents. PMID- 4214384 TI - [Anesthesia by Chinese traditional medicine. A preliminary analysis of 150 cases]. PMID- 4214385 TI - [Anesthesia using traditional Chinese herb medicine in operations on patients with shock. An analysis of 232 cases]. PMID- 4214386 TI - Investigations on alum-precipitated pyridine-extracted allergens. II. Sensitization studies in guinea pigs. PMID- 4214388 TI - Schistosomiasis in Nyanza Province, Kenya, 1 Rusinga Island. PMID- 4214387 TI - Intestinal manifestations of Fabry's disease. PMID- 4214390 TI - The study of the mutagenic properties of an insecticide from the carbamate group- Sevin. PMID- 4214389 TI - The structural role of lipids in mitochondrial and sarcoplasmic reticulum membranes. Freeze-fracture electron microscopy studies. PMID- 4214391 TI - The substrate for integration in the central pain pathways. PMID- 4214392 TI - [Diet of the patient in stress]. PMID- 4214393 TI - [Part I: use of industrial dyes and problems of dye purification. A. Use of industrial dyes: their quality, their utility in morphological work, their characterization by the manufacturer. 1. Definition of dyes]. PMID- 4214394 TI - [Part II; standardization and normalization of dyes. 12. Introduction: relationship of the dye commission to the professional standards committee in medicine]. PMID- 4214395 TI - [Post-traumatic ossification of the long muscles of the neck]. PMID- 4214397 TI - Crystallisation of a modified fibrinogen. PMID- 4214396 TI - A metabolic inquiry into the iridescent lysis of agar lawns of Pseudomonas aeruginosa strain 227. PMID- 4214398 TI - Spontaneous regression of cancer. PMID- 4214399 TI - Bilateral fibrous hyperplasia of the palate. PMID- 4214400 TI - Counterimmunoelectrophoresis: an adjunct to bacterial culture in the diagnosis of meningococcal meningitis. PMID- 4214401 TI - Roentgen findings of pseudo-Hurler polydystrophy in the adult, with a note on cephalometric changes. PMID- 4214402 TI - Growth and development of the fetal Rhesus monkey. V. Fatty acids of phospholipids in fetal lung. PMID- 4214403 TI - Health care in the United Kingdom. The changing scene. PMID- 4214404 TI - Growth hormone (GH)-releasing activity of TRH and GH-lowering effect of dopaminergic drugs in acromegaly: homogeneity in the two responses. PMID- 4214405 TI - Growth of the peritrich Opercularia coarctata in axenic culture. PMID- 4214406 TI - [On the encephalotrophic action of hydergine. Clinical study]. PMID- 4214407 TI - [Further observations on "automation-like" existence under long-term lithium therapy]. PMID- 4214408 TI - Diphtheria tox+ gene expressed in corynebacterium species other than C. diphtheriae. PMID- 4214409 TI - Lecithin-cholesterol acyltransferase activity in diabetes mellitus and the effect of insulin on these cases. PMID- 4214410 TI - [Initial results in the treatment of diabetes mellitus with an association of glibenclamide and phenformin]. PMID- 4214411 TI - Aleutian disease of mink. PMID- 4214412 TI - [Lactic acidosis induced by phenformin treated with glucose and insulin]. PMID- 4214413 TI - Genetic location of two mutations affecting the lysyl-transfer ribonucleic acid synthetase of Bacillus subtilis. AB - Two mutations (lysS1 and lysS2), each independently resulting in a thermosensitive, lysyl-transfer RNA synthetase (l-lysine: tRNA ligase [adenosine 5'-monophosphate] EC 6.1.1.6), have been mapped on the Bacillus subtilis chromosome between purA16 (adenine requirement) and sul (sulfanilamide resistance). They are linked by transformation with sul (70 to 74% cotransfer) in the order purA16-lysS1-lysS2-sul. The mutant loci are either in the same gene or in two closely linked genes. They are not linked to the tryptophanyl-tRNA synthetase structural gene or to the lys-1 locus. PMID- 4214414 TI - Mitotic recombination maps in Drosophila melanogaster. PMID- 4214415 TI - Genetic structure in the United Kingdom. PMID- 4214416 TI - Genetic studies on hybrid populations. 3. Blood pressure in an American black community. PMID- 4214417 TI - Genetic transformation of biosynthetically defective Neisseria gonorrhoeae clinical isolates. AB - Deoxyribonucleic acid (DNA) and chemically defined media were used in transformation tests of 51 strains of Neisseria gonorrhoeae which exhibited various biosynthetic defects when isolated from patients. These auxotrophic gonococci had one or more nutritional requirements involving proline, methionine, arginine, hypoxanthine, uracil, and thiamine pyrophosphate (THPP). DNA from a clinical isolate which did not require these compounds for growth on defined medium transformed each of the auxotrophic markers of all 51 recipient populations. Ten isolates had defects involving the synthesis of THPP; four strains (designated Thp(-)) had a growth requirement that was satisfied only by THPP, whereas the requirement of six strains (designated Thi(-)) was satisfied by either thiamine or THPP. DNA from Thp(-) donors elicited transformation of Thp(-) as well as Thi(-) recipients. Reciprocally, DNA from a Thi(-) donor transformed both Thi(-) and Thp(-) recipients. Furthermore, DNA from other auxotrophic gonococci had transforming activity for some phenotypically similar auxotrophic recipients. The findings indicate the existence of various nonidentical genetic defects which block reactions in the biosynthesis of proline, methionine, arginine, hypoxanthine, and THPP. Routine cultures from patients with gonorrhea were the source of these auxotrophic strains of N. gonorrhoeae; the various nutritional requirements were identified by a recently described system of gonococcal auxotyping. The transformation test results verify the hereditary basis of the auxotypes, establish that many different mutations exist in potentially virulent gonococci, and illustrate the value of these auxotrophic mutants for studies of the genetic structure and evolution of natural populations of gonococci. PMID- 4214418 TI - Practicability of influenza surveillance by virus culture of children. PMID- 4214419 TI - Identification of a nuclear protein matrix. PMID- 4214420 TI - Identification of two plasmids determining resistance to tetracycline and to erythromycin in group D streptococcus. PMID- 4214421 TI - [Routine methods for fibrinogen determination]. PMID- 4214422 TI - [Xantine oxidoreductase activity in the aorta wall of the rat (author's transl)]. PMID- 4214423 TI - [Continuous measurement of cellular deformability, using a diffractometric method]. PMID- 4214424 TI - [Continuous slow flow enteral resuscitation applied to postoperative severe acute enteritis]. PMID- 4214425 TI - [Continuous slow flow enteral resuscitation applied to severe malnutrition (260 cases)]. PMID- 4214426 TI - [Continuous slow flow enteral resuscitation applied to upper digestive hemorrhages (50 cases)]. PMID- 4214427 TI - [Continuous slow flow enteral resuscitation. Material and technic]. PMID- 4214428 TI - [Continuous slow flow enteral resuscitations. Overall view of the method. Technic, physiological effects, therapeutic applications]. PMID- 4214429 TI - Dilution curves studies in coumarin plasmas and in artificially depleted abnormal control plasmas. PMID- 4214430 TI - Reaction of mucous membranes of the maxillary sinus and the nasal cavity to experimental periapical inflammation in monkeys. PMID- 4214431 TI - Location of prophage H90 on the chromosome of Pseudomonas aeruginosa strain PAO. PMID- 4214433 TI - Functionally stable osteosynthesis in the mandible. PMID- 4214432 TI - Additional applications of the hexagonal conformation to calcitonin, myoglobin and other proteins of known sequence. PMID- 4214434 TI - Quantitative determination of polychlorinated biphenyls--a computer approach. PMID- 4214435 TI - Quantitative distribution of Brucella antibody amongst immunoglobulin classes in vaccinated and infected cattle. PMID- 4214436 TI - Inactivation of soluble bovine milk galactosyltransferase (lactose synthetase) by sulfhydryl reagents and trypsin. Protection by substrates and products. PMID- 4214437 TI - Reactivity of monkey erythrocytes in immune adherence. PMID- 4214438 TI - Treatment of acute gonococcal urethritis in Bangkok, Thailand. PMID- 4214439 TI - Treatment of experimentally induced Pseudomonas aeruginosa otitis externa in the dog by lavage with EDTA-tromethamine-lysozyme. PMID- 4214440 TI - Treatment of facial asymmetries by one-stage maxillary and mandibular bilateral osteotomies. PMID- 4214441 TI - [Protocol of the members convention of the Society for Histochemistry in Dusseldorf on 10-9-71]. PMID- 4214442 TI - [Photographic emulsions and their application in dosimetry (author's transl)]. PMID- 4214443 TI - Serotonin distribution in the limbic system of the rat. PMID- 4214444 TI - The tonotopic organization of the auditory thalamus of the squirrel monkey (Saimiri sciureus). PMID- 4214445 TI - [Postoperative side-effects of neostigmine. Statistical study of 400 operated patients]. PMID- 4214446 TI - Stentor tartari sp. n. from India. PMID- 4214447 TI - Cryptosporidiosis in a calf. PMID- 4214448 TI - Aflatoxin Q1: a major metabolite of aflatoxin B1 produced by human liver. PMID- 4214449 TI - [Neutral fats and cholesterol in freeze-etched casts]. PMID- 4214450 TI - [Australia antigen (AgHB) and glomerulonephritis]. PMID- 4214451 TI - The transition from tadpole to frog haemoglobin during natural amphibian metamorphosis. II. Immunofluorescence studies. PMID- 4214452 TI - The treatment of anterior communicating aneurysms by proximal anterior cerebral artery ligation. PMID- 4214453 TI - The treatment of long standing bilateral fracture non- and mal-union in atrophic edentulous mandibles. PMID- 4214454 TI - Electrocardiographic changes in Panamanian Rattus rattus naturally infected by Trypanosoma cruzi. PMID- 4214455 TI - Electroencephalographic correlates of epilepsy in Nigerian children. PMID- 4214456 TI - [Controlled clinical study of a new oral antidiabetic formed by a glibenclamide phenformin association]. PMID- 4214457 TI - Electron beam treatment of early glottic lesions. PMID- 4214458 TI - Electron microscopy of frog photoreceptor outer segments after fixation with aldehydes. PMID- 4214459 TI - Electron probe x-ray analysis of siderosomes in haemarthrotic articular cartilage. PMID- 4214460 TI - Electron therapy for intraocular tumours. PMID- 4214461 TI - Rosette-forming T lymphocytes and cell-mediated immunity in malnutrition. AB - The frequency of rosette-forming thymus-dependent lymphocytes was reduced in the peripheral blood of malnourished infants and children. The reduced frequency parallelled the impairment of delayed hypersensitivity response to 2, 4 dinitrochlorobenzene and decreased DNA synthesis by lymphocytes challenged with phytohaemagglutinin. The abnormalities were reversed on nutritional improvement. PMID- 4214462 TI - [A study comparing immunoprecipitation and hemagglutination tests for hydatidosis (author's transl)]. PMID- 4214463 TI - Serotyping of Pseudomonas aeruginosa. PMID- 4214465 TI - Evaluating the potential for occurrence of aflatoxins in black sunflower seeds. PMID- 4214464 TI - Unusual manifestations of neurofibromatosis. PMID- 4214466 TI - Evaluation of a simple screening test for serum anti-trypsin activity. PMID- 4214467 TI - Evaluation of commercially available antisera for serotyping of Pseudomonas aeruginosa. AB - Commercially available O antisera have been compared with a standard pyocine typing method in the investigation of 156 strains of Pseudomonas aeruginosa. A third of the strains belonged to serotypes 3 or 6 and 42.3% to pyocine type 1. Good differentiation of strains belonging to the predominant serotypes was achieved by pyocine typing. Although routine use of both methods provides a more complete discrimination between strains, the simplicity of serotyping renders it more suitable for use in the smaller laboratory, where only one method may be feasible. If desired, pyocine typing can be reserved for the strains which cannot be distinguished serologically. PMID- 4214468 TI - Evaluation of nationwide health costs of air pollution and cigarette smoking. PMID- 4214469 TI - Evaluation of specific protein analysis in a non-teaching hospital laboratory. PMID- 4214470 TI - Evaluation of the gibbon (Hylobates lar lar) as a laboratory primate-use of gibbons. PMID- 4214471 TI - Evaluation of the Gonosticon Dri Dot test in females with a low incidence of gonorrhea. AB - A group of 765 females attending a Planned Parenthood Clinic was screened for gonorrhea by inoculating Thayer-Martin plates and Transgrow bottles with specimens from the cervix. Blood was obtained at the same time and tested for anti-gonococcal antibody by using the Gonosticon Dri Dot test. In this low incidence group, 18 positive cultures were detected by culture on Thayer-Martin plates, whereas Transgrow detected only 15 positive cultures. Of the 18 patients with gonorrhea, 11 exhibited reactive serum (agglutination of the latex particles). In the total population, 64% of the patients had nonreactive serum (no agglutination) and negative cultures; 25% had reactive serum and negative cultures. When this latter group was subdivided on the basis of race, blacks and Latin Americans were found to have a higher incidence of reactive serum with a corresponding negative culture than was found in whites. Patients who were originally culture positive and nonreactive in the Gonosticon Test were retested; three out of four patients retested within 6 to 11 days after the initial screening had converted to a positive Gonosticon test. PMID- 4214472 TI - Evaluation of thyroid status with "effective thyroxine ratio" (E.T.R.). PMID- 4214473 TI - A double-blind trial of vitamin E in angina pectoris. PMID- 4214474 TI - Conduction defects in the aging heart. PMID- 4214475 TI - Production of extracellular substances by different virulent strains of Pseudomonas aeruginosa. PMID- 4214476 TI - A study of the relationship between Nocardia and Mycobacterium diernhoferi--a typical fast growing Mycobacterium. PMID- 4214477 TI - Unique presence of 2-methylthio-ribosylzeatin in the transfer ribonucleic acid of the bacterium Pseudomonas aeruginosa. PMID- 4214478 TI - Tissue pyridoxal phosphate concentration and pyridoxaminephosphate oxidase activity in riboflavin deficiency in rats and man. PMID- 4214479 TI - Tissue receptor for cholera exotoxin: structural requirements of G11 ganglioside in toxin binding and inactivation. PMID- 4214480 TI - Influence of glyburide on the antidiuretic response induced by 1-deamino-8-D arginine vasopressin (DDAVP) in patients with pituitary diabetes insipidus. PMID- 4214481 TI - A fluid system for the cultivation, light microscope examination and manipulation of obligate anaerobes. PMID- 4214482 TI - Cellular antigens of staphylococci. PMID- 4214483 TI - Cellular mechanisms of urinary acidification. PMID- 4214484 TI - Sporulation in Bacillus subtilis 168. Control of synthesis of alkaline phosphatase. PMID- 4214485 TI - [Results of longterm therapy with trimethoprim-sulfamethoxazol in Malta fever of children (author's transl)]. PMID- 4214486 TI - Sodium cromoglycate BP in the prevention of exercise-induced asthma. PMID- 4214487 TI - [Serum prolactin fluctuation caused by TRH tolerance test in thyroid disorders]. PMID- 4214488 TI - [Immunization hemolytic disease of the newborn (HDN) Rh with anti-D immunoglobulins]. PMID- 4214489 TI - [Immunofluorescence optical studies for the differentiation of monoclonal and polyclonal increases in immunoglobulin producing bone marrow cells]. PMID- 4214490 TI - Uncoupling of photophosphorylation in spinach chloroplasts by the ionophorous antibiotic A23187. PMID- 4214491 TI - Disruption of human erythrocytes with 7-oxa-13-prostynoic acid. PMID- 4214492 TI - [Natural immunologic tolerance of rhesus- and ABO-incompatible pregnancies]. PMID- 4214493 TI - Measurement of bound and free endotoxin by the Limulus assay. PMID- 4214494 TI - Measurement of urinary fibrinogen-related material: methodologic aspects. PMID- 4214495 TI - Mercury effects from chronic and acute doses on fixed-interval operant behavior of female squirrel monkeys. PMID- 4214496 TI - The use of inactivators in the evaluation of disinfectants. AB - Since the earliest days of disinfectant testing bacteriostatic effect has misled many workers in this field. This problem has long been appreciated by some and a considerable battery of neutralizers has been employed, often with great success. Other anti-bacteriostatic measures, used without control, fail to revive damaged though viable organisms.This paper sets out to describe some of the problems that are encountered in this confused field and the means whereby they may be overcome. PMID- 4214497 TI - Discussion of classification. PMID- 4214498 TI - Computer calculations of dose for irregularly shaped fields for cobalt-60 and 6 MV photons. PMID- 4214499 TI - Agglutination of Trypanosoma cruzi by concanavalin A. PMID- 4214500 TI - The value of heparin in the hyperalimentation of infants and children with a fat emulsion. PMID- 4214501 TI - The value of intravenous prostaglandin E2 after intra-uterine death. PMID- 4214502 TI - Adjuvant treatment of blunt pancreatic trauma. PMID- 4214503 TI - Pyruvate kinase of Streptococcus lactis. AB - The kinetic properties of pyruvate kinase (ATP:pyruvate-phosphotransferase, EC 2.7.1.40) from Streptococcus lactis have been investigated. Positive homotropic kinetics were observed with phosphoenolpyruvate and adenosine 5'-diphosphate, resulting in a sigmoid relationship between reaction velocity and substrate concentrations. This relationship was abolished with an excess of the heterotropic effector fructose-1,6-diphosphate, giving a typical Michaelis-Menten relationship. Increasing the concentration of fructose-1,6-diphosphate increased the apparent V(max) values and decreased the K(m) values for both substrates. Catalysis by pyruvate kinase proceeded optimally at pH 6.9 to 7.5 and was markedly inhibited by inorganic phosphate and sulfate ions. Under certain conditions adenosine 5'-triphosphate also caused inhibition. The K(m) values for phosphoenolpyruvate and adenosine 5'-diphosphate in the presence of 2 mM fructose 1,6-diphosphate were 0.17 mM and 1 mM, respectively. The concentration of fructose-1,6-diphosphate giving one-half maximal velocity with 2 mM phosphoenolpyruvate and 5 mM adenosine 5'-diphosphate was 0.07 mM. The intracellular concentrations of these metabolites (0.8 mM phosphoenolpyruvate, 2.4 mM adenosine 5'-diphosphate, and 18 mM fructose-1,6-diphosphate) suggest that the pyruvate kinase in S. lactis approaches maximal activity in exponentially growing cells. The role of pyruvate kinase in the regulation of the glycolytic pathway in lactic streptococci is discussed. PMID- 4214504 TI - Activation of complement in anaphylactoid reactions in connection with infusion of dextran. PMID- 4214505 TI - Activation of lipolytic activity in Streptococcus lactis by ultraviolet irradiation. PMID- 4214506 TI - Active transport of choline by a marine pseudomonad. AB - A marine pseudomonad, BAL-31, accumulates the phospholipid nitrogen base, choline, although no detectable amount of choline is incorporated into polar lipids. Metabolic inhibitors such as cyanide and azide block the uptake process as does starving for oxygen by using nitrogen gas. Only very close structural analogues show any inhibition of transport, indicating that the uptake process has great structural specificity. The export of choline out of the cells is also an energy-dependent process and is markedly reduced during oxygen depletion. The constitutive level of choline transport is increased by approximately a factor of three after a brief induction period. Two other gram-negative bacteria also accumulate choline, whereas a gram-positive bacterium, Bacillus subtilis, and a yeast, Saccharomyces cerevisiae, fail to show any detectable accumulation. PMID- 4214507 TI - A novel combination of liquid chromatography and electron capture detection in the analysis of pesticides. PMID- 4214508 TI - A review of some wild land mammals of Palawan, Republic of the Philippines. PMID- 4214509 TI - The viruses of hepatitis. PMID- 4214510 TI - The vitreous carbon tooth root replacement system: a surgical discipline. PMID- 4214511 TI - [In vitro study of the maturation of the 17 S precursor of ribosomal RNA 16 S of E. coli]. PMID- 4214512 TI - [In-vitro synergism between beta-lactamines. I. Anti-bacterial action of ampicillin-cloxacillin combination on Gram-negative bacteria]. PMID- 4214513 TI - [In vivo models on the passage of amino acids through the rumen wall. 2. Permeability of the rumen wall for individual amino acids]. PMID- 4214514 TI - A new fixation technique for the electron microscopic study of pulmonary surfactant. PMID- 4214515 TI - A new method of gamma-ray osteodensitometry of the mandible. PMID- 4214516 TI - A new species of Caryospora Leger, 1904 (Sporozoa: Eimeriidae) from an Australian snake. PMID- 4214517 TI - A new type of sodium transport inhibitor in the toad bladder. PMID- 4214518 TI - An experimental model of alcohol feeding and liver injury in the baboon. PMID- 4214519 TI - Fatty liver and kidney syndrome in chicks. Effects on liver and kidney of diets causing the syndrome. PMID- 4214521 TI - Study of oxacillin levels in human serum and lung tissue. PMID- 4214520 TI - Study of heat resistance in a bacterial nucleosidase. PMID- 4214522 TI - Study of the factors affecting the mutagenic activity of nitrosoethylurea. PMID- 4214523 TI - Daily variations in the production of aflatoxins by Aspergillus flavus NRRL-3145 following exposure to 60 Co irradiation. PMID- 4214524 TI - Assay, kinetics, and lysosomal localization of an acid cholesteryl esterase in rabbit aortic smooth muscle cells. PMID- 4214525 TI - A fly's leap from paralysis. PMID- 4214526 TI - Six-year follow-up of glutaraldehyde-preserved heterografts. With particular reference to the treatment of congenital valve malformations. PMID- 4214527 TI - [Polyneuropathy due to diphenylhydantoin overdosage]. PMID- 4214528 TI - Biosynthesis of thyrotropin releasing factor by newt (Triturus viridescens) brain in vitro. Isolation and characterization of thyrotropin releasing factor. PMID- 4214529 TI - Analysis of pharmacokinetic properties of nine tetracycline analogues in dairy cows and ewes. PMID- 4214530 TI - Analysis of the chromosome aberrations induced by x-rays in somatic cells of Drosophila melanogaster. AB - A technique has been perfected for enabling good microscope preparations to be obtained from the larval ganglia of Drosophila melanogaster. This system was then tested with X-rays and an extensive series of data was obtained on the chromosome aberrations induced in the various stages of the cell cycle.-The analysis of the results obtained offers the following points of interest: (1) There exists a difference in radio-sensitivity between the two sexes. The females constantly display a greater frequency of both chromosome and chromatid aberrations. They also display a greater frequency of spontaneous aberrations. (2) In both sexes the overall chromosome damage is greater in cells irradiated in stages G(2) and G(1). These two peaks of greater radiosensitivity are produced by a high frequency of terminal deletions and chromatid exchanges and by a high frequency of dicentrics, respectively. (3) The aberrations are not distributed at random among the various chromosomes. On the average, the Y chromosome is found to be more resistant and the breaks are preferentially localized in the pericentromeric heterochromatin of the X chromosome and of the autosomes. (4) Somatic pairing influences the frequency and type of the chromosome aberrations induced. In this system, such an arrangement of the chromosomes results in a high frequency of exchanges and dicentrics between homologous chromosomes and a low frequency of scorable translocations. Moreover, somatic pairing, probably by preventing the formation of looped regions in the interphase chromosomes, results in the almost total absence of intrachanges at both chromosome and chromatid level. PMID- 4214531 TI - Ionizing radiations, genetic loads and population fitness, a review. PMID- 4214532 TI - RH (D)-isoimmunization of Japanese women. PMID- 4214534 TI - [2. Dyes and dye problems in histology and histochemistry]. PMID- 4214533 TI - [7. Dye purification through crystallization]. PMID- 4214535 TI - Myo-Inositol dehydrogenase(s) from Acetomonas oxydans. Optimization of conditions for solubilization of membrane-bound enzyme. AB - Methods are described for the first reported successful isolation of the soluble form of the membrane-bound myo-inositol dehydrogenase(s) from Acetomonas oxydans. Conditions for optimum yields of active enzyme in a crude membrane-free protein extract were established. The relevant conditions are (a) cell rupture by solid shearing, (b) solubilization of the complete 60000g pellet with sodium deoxycholate at pH7.2, (c) rapid separation of the released protein from sodium deoxycholate by gel chromatography. PMID- 4214536 TI - The Kniest syndrome. PMID- 4214537 TI - [B. Methods and results of dye purification. 6. Course of purification of a dye, demonstrated in the example of acridine orange]. PMID- 4214538 TI - The N-terminal amino acid sequence of Bacillus subtilis alpha-amylase. PMID- 4214539 TI - [3. Observations on the problems of dye configuration and its influence on the color]. PMID- 4214540 TI - [Benign bone tumors of the nose and paranasal sinuses in childhood. Review of cases in the Hospital Infantilede Mexico]. PMID- 4214542 TI - Antigen specificity and immunogenic capacity of 3m KCl cell extracts from ascites tumour ATPCplus. PMID- 4214541 TI - [Fat absorption facilitated by using pancreatic enzymes in malnourished children]. PMID- 4214543 TI - Immunological studies on a slow type bisalbuminae-mia (alloalbuminaemia). PMID- 4214544 TI - [Standard procedure in the use of immunodiffusion for detection of staphylococcal enterotoxins and A and B enterotoxic strains]. PMID- 4214545 TI - [Interrelations of pterinic pigments and ommochromic pigments in Drosophila melanogaster. I. Analysis of the chemotype of mutants v, cn, cd, st, of the mutant mal and of the respective double mutants]. PMID- 4214546 TI - [Interrelations of pterinic pigments and ommochromic pigments in Drosophila melanogaster. II. Possible mechanism of biotransformation of 7,8-dihydrobiopterin into sepiapterin]. PMID- 4214547 TI - [Changes in muscular glycogen synthetase activity in rats treated with actinomycin D or cycloheximide]. PMID- 4214548 TI - [Different behavior of the PPD tuberculin skin test in human tubercular infection and nosology]. PMID- 4214549 TI - Miliary tuberculosis twice. PMID- 4214550 TI - Lead content of neuromuscular tissue in amyotrophic lateral sclerosis: case report and other considerations. PMID- 4214551 TI - The relationship of extrinsic and intrinsic metal ions to the specificity of a dipeptidase from Escherichia coli B. PMID- 4214552 TI - Stereospecific irreversible inhibition of histidine ammonia-lyase by L-cysteine. PMID- 4214553 TI - tRNA and tRNA aminoacyl synthetases of chloroplasts, mitochondria and cytoplasm from Euglena gracilis. PMID- 4214555 TI - Isolation and purification of Rh(c) antigen. PMID- 4214554 TI - Actinomycin D binding to 37 RC and HeLa cell lines. PMID- 4214556 TI - Haemolysis of intact human erythrocytes by purified cobra venom phospholipase A2 in the presence of albumin and Ca2+. PMID- 4214557 TI - The effect of catecholamines on ion transport in the toad bladder. PMID- 4214558 TI - Protein and electroretinogram changes in the alleles of the norp AP12 Drosophila phototransduction mutant. PMID- 4214559 TI - Some kinetic properties of M2-type pyruvate kinase from rat liver at physiological Mg2+ concentration. PMID- 4214560 TI - Studies on the properties of peptide hydrolases in the brush-border and soluble fractions of small intestinal mucosa of rat and man. PMID- 4214561 TI - Chicken alpha2-proteinase inhibitor: a serum protein homologous with ovoinhibitor of egg white. PMID- 4214562 TI - Primary platelet aggregation. Energy metabolism and the effect of inhibitors. PMID- 4214563 TI - Sequence of candicidin action on yeast cells. PMID- 4214564 TI - Purification of human serum albumin by affinity chromatography. PMID- 4214565 TI - Some hydrodynamic properties of spore peptidoglycan. PMID- 4214566 TI - The immunological heterogeneity of the proteins extracted from Bos taurus erythrocyte membranes by EDTA. PMID- 4214567 TI - The mechanism of iron exchange between synthetic iron chelators and rabbit reticulocytes. PMID- 4214568 TI - [Oxygen consumption by blue-green algae]. PMID- 4214569 TI - Circle-elipse discrimination in monkeys: comparison of titration schedules with the method of limits. PMID- 4214570 TI - Measurement of diffusion coefficients of meningococcal polysaccharide by optical mixing spectroscopy. I. A preliminary characterization on the aggregation of the group C polysaccharide. PMID- 4214571 TI - Letter: Studies on the binding of amyloglucosidase to inert proteins. PMID- 4214572 TI - An acquired inhibitor of fibrin stabilization associated with isoniazid therapy: clinical and biochemical observations. PMID- 4214573 TI - [The problem of activation of the coagulation system in preserved blood]. PMID- 4214575 TI - Effect of nitroglycerin on phosphorylase activity of the myocardium. PMID- 4214574 TI - Factor VIII immunological assay. An evaluation of several methods using whole plasma. PMID- 4214576 TI - Investigation of the action of a reducing agent on the effector functions of rabbit gamma G antibodies. PMID- 4214577 TI - Letter: T.S.H. level and thyroid function. PMID- 4214578 TI - Letter: Post-partum rubella vaccination, anti-D immunoglobulin, and blood transfusion. PMID- 4214579 TI - Indications for systemic antibiotic prophylaxis in neutropenic patients. AB - Four patients with malignant blood disease and neutropenia developed apparently localized infective lesions of the skin or conjunctiva from which Pseudomonas aeruginosa was cultured. In spite of appropriate local antimicrobial treatment all patients developed pseudomonas septicaemia within a short period and three died. It is argued that the isolation of pseudomonads from apparently localized lesions in patients with compromised antibacterial defences is an indication for systemic antibiotic therapy. PMID- 4214580 TI - Letter: Safety and fibreoptic bronchoscopy. PMID- 4214581 TI - Neisseria meningitidis in urogenital infection. PMID- 4214582 TI - Prostatitis after urethritis in Singapore. PMID- 4214583 TI - Letter: Prepubertal gonorrhoea. PMID- 4214584 TI - Pseudomonas aeruginosa infection in the skin of a dog: a case report. PMID- 4214585 TI - East Coast fever: titration in cattle of suspensions of Theileria parva derived from ticks. PMID- 4214586 TI - [Origin and reversibility of hydronephrosis in multirenicular kidneys. II. Function studies and radioisotope clearance in young midget pigs]. PMID- 4214587 TI - [Site of action of the coronary medication, carbochromen]. PMID- 4214588 TI - [Research on the variations of catalase activity in nonproliferating suspensions of Pseudomonas fluorescens (R type). III. Influence of free SH groups]. PMID- 4214589 TI - [Nature of the cardiovascular effects of bradykinin in the rat]. PMID- 4214590 TI - [Rickettsia and macrophages in vitro]. PMID- 4214591 TI - A study on the effect of lysolecithin and phospholipase A on membrane-bound galactosyltransferase. PMID- 4214592 TI - Characterization of the esterases of feline serum. PMID- 4214593 TI - Template specificity and subunits of RNA polymerase from asporogenous mutants of Bacillus subtilis. PMID- 4214594 TI - A cytokinin oxidase in Zea mays. PMID- 4214595 TI - Recovery of SD chromosomes from Drosophila melanogaster males when heterozygous with structurally different second chromosomes. PMID- 4214596 TI - Surgery in premalignant lesions. PMID- 4214597 TI - Characteristics of the plasma disappearance of (3H)-thyrotropin-releasing hormone in the rat. PMID- 4214598 TI - Effects of guanethidine and imidazole on histamine metabolism. PMID- 4214599 TI - The isolation of Neisseria species from unusual sites. AB - The isolation of N. gonorrhoeae from the pharynx of four patients and N. meningitidis from the genital tract of six patients is described. Sexual transmission seemed the most likely means of acquiring these organisms. Three out of four patients harbouring gonococci in the pharynx were asymptomatic, while four of six patients with genital meningococci were symptom-free. The isolation of meningococci from the genital tract coincided with an unusually high incidence of meningococcal disease in the community. PMID- 4214600 TI - Diffuse plasma cell infiltration of the small intestine with malabsorption associated to IgA monoclonal gammapathy. PMID- 4214601 TI - Lymphomatoid granulomatosis of the skin: light microscopic and ultrastructural studies. PMID- 4214602 TI - IgG myeloma, Sia test, and serum hyperviscosity. PMID- 4214603 TI - Spontaneous haemophilia in a genotypically normal female. A family study. PMID- 4214604 TI - Disseminated intravascular coagulation during a fatal Mycoplasma pneumoniae infection. PMID- 4214605 TI - Letter: Potential hazards associated with the use of 1-methyl-1-nitrosourea (NSC 23909). PMID- 4214606 TI - Serum concentrations of haptoglobin and hemopexin in favism and thalassemia. PMID- 4214607 TI - Experimental study on haematotoxic and leukaemogenic effects of trichlorophone and dimethoate. PMID- 4214608 TI - Central nervous system complications after combination treatment with adriamycin (NSC-123127) and 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388). PMID- 4214609 TI - Study of post-splenectomy thrombocytopoiesis with 75Se-methionine in mice. PMID- 4214610 TI - Functional characteristics of chronic monocytic "leukemia". PMID- 4214611 TI - Solubilization and activation of mammalian melanoma particulate tyrosinase by lipase digestion. PMID- 4214612 TI - Occurrence of Mason-Pfizer monkey virus in healthy rhesus monkeys. PMID- 4214613 TI - An assay for iduronate sulfatase (Hunter corrective factor). PMID- 4214614 TI - Biosynthesis of chondroitin sulfate. Purification of UDP-D-xylose:core protein beta-D-xylosyltransferase by affinity chromatography. PMID- 4214615 TI - Cross-reactivity of the membrane teichoic acid of Streptococcus faecalis N.C.I.B. 8191 in antipneumococcal type XII and type XVI sera. PMID- 4214616 TI - The possible biological significance of Fc receptors on mammalian lymphocytes and tumor cells. PMID- 4214617 TI - Relative activities of alpha-ecdysone and beta-ecdysone for the differentiation in vitro of Drosophila melanogaster imaginal discs. PMID- 4214618 TI - A hemagglutination inhibition technique for detection of immunoglobulins in supernatants of human lymphoblastoid cell lines. PMID- 4214619 TI - The program of protein synthesis during heterocyst differentiation in nitrogen fixing blue-green algae. PMID- 4214620 TI - [Clinical importance of the venous preparation Anavenol drops]. PMID- 4214621 TI - [Studies on gonorrhea. III. Critical evaluation of bacteriological findings and results of culture examinations]. PMID- 4214622 TI - [Prognosis of petit mal epilepsy--absence in childhood]. PMID- 4214623 TI - Studies on the passage of alpha-chymotrypsin across the intestine. III. Quantitation of alpha-chymotrypsin in the mesenteric perfusate by single radial immunodiffusion. PMID- 4214624 TI - [2 cases of Rieger's syndrome. Malformations of the anterior segment associated with facial bone abnormalities]. PMID- 4214625 TI - [Ocular infection due to pyocyanic. Search for the pathogen]. PMID- 4214626 TI - Regional myocardial function during acute coronary artery occlusion and its modification by pharmacologic agents in the dog. PMID- 4214627 TI - Constrictive pericarditis in childhood due to mediastinal irradiation. PMID- 4214628 TI - Evaluation of the ability of echocardiography to measure acute alterations in left ventricular volume. PMID- 4214629 TI - Maximum treadmill exercise electrocardiography in female patients. PMID- 4214630 TI - Chagasic cardiopathy. Antibodies reacting with plasma membrane of striated muscle and endothelial cells. PMID- 4214631 TI - Letter: The action of nitroglycerin. PMID- 4214632 TI - Anaphylactic sensitivity to human seminal fluid. PMID- 4214633 TI - Glutaraldehyde-pollen-tyrosine: clinical and immunological studies. PMID- 4214634 TI - IgE--antibodies and skin test reactions to a detergent--enzyme in Swedish consumers. PMID- 4214635 TI - Emergence of basophils at sites of local allergic reactions using a skin vesicle test. PMID- 4214636 TI - Measurement of ceruloplasmin from its oxidase activity in serum by use of o dianisidine dihydrochloride. PMID- 4214637 TI - A note on the estimation of thyroxine-binding parameters. PMID- 4214638 TI - Prolactin, TSH, LH and FSH responses to a combined LHRH-TRH test at different stages of the menstrual cycle. PMID- 4214639 TI - Electromyography of oral-facial musculature in craniocarpaltarsal dysplasia (Freeman-Sheldon syndrome). PMID- 4214640 TI - A linkage study of phenylketonuria. PMID- 4214641 TI - Absorption and decomposition of potassium-35S-phenoxymethyl penicillin. PMID- 4214642 TI - Burns in children. PMID- 4214643 TI - Detection of mucopolysaccharidoses by sulphate incorporation into stimulated lymphocytes. PMID- 4214644 TI - [Camazepam (B 5833) in therapy of angina pectoris]. PMID- 4214645 TI - L-leucyl-and L-phenylalanyl-beta-naphthylamidase activities in the tissues of the sea mussel (Mytilus edulis L.). PMID- 4214646 TI - The soluble cuticular proteins form three arthropod species: Scylla serrata (Decapoda: Portunidae), Boophilus microplus (Acarina: Ixodidae) and Agrianome spinicollis (Coleoptera: Cerambycidae). PMID- 4214647 TI - Serum protein relationships among several species of Galapagos lava lizards (genus Tropidurus). PMID- 4214648 TI - Psychological characteristics of long-term mental patients: some implications for treatment. PMID- 4214649 TI - Staphylococcal alpha antitoxin and antibodies to extracellular antigens of staphylococci and micrococci in the serums of dairy cows. PMID- 4214650 TI - "Psychotropic" action of sex hormones: computerized EEG in establishing the immediate CNS effects of steroid hormones. PMID- 4214651 TI - Low-dose haloperidol as antiemetic treatment in gastrointestinal disorders: a double-blind study. PMID- 4214652 TI - Psychomotor effects of a new CNS stimulant, Abbott 34519. PMID- 4214653 TI - Controlled trial of guanethidine and methyldopa in moderate hypertension. PMID- 4214654 TI - Circulatory effects of fenfluramine in obese hypertensive patients. PMID- 4214655 TI - Arterial hypertension--northwest Florida public health survey. II. Diagnosis and treatment. PMID- 4214656 TI - Pharmaceutics of cephapirin sodium (Cefadyl) a new semisynthetic cephalosporin - part III. PMID- 4214657 TI - A system for clinical drug development in the United States. PMID- 4214658 TI - A double-blind comparison of pimozide vs. trifluoperazine in schizophrenic outpatients. PMID- 4214659 TI - A comparison of the relative clinical efficacy of two chlorpromazine (CPZ) preparations. PMID- 4214660 TI - The effects of dimethyl sulfoxide on snake venom toxicity in vivo and on the efficacy of antivenins. PMID- 4214661 TI - Minocycline administered intravenously: pharmacological activity and clinical experience. PMID- 4214662 TI - Pharmacokinetics of cefazolin, a new cephalosporin antibiotic, in normal and uraemic patients. PMID- 4214663 TI - Antihypertensive effects of metolazone (zaroxolyn). PMID- 4214664 TI - Long-term effect of halofenate on serum lipids. PMID- 4214665 TI - Comparative study of bufexamac (Droxaryl) ointment and of its excipient on psoriasis cases: double-blind test. PMID- 4214666 TI - Etiology and management of intestinal gas. PMID- 4214667 TI - Acetaminophen with codeine for the relief of severe pain in postpartum patients. PMID- 4214668 TI - Treatment of musculoskeletal pain and associated anxiety with an ethoheptazine aspirin-meprobamate combination (equagesic): a controlled study. PMID- 4214669 TI - The effect of Ru-Vert and its components on post-rotatory motor performance. PMID- 4214670 TI - Comparison of triazolam, flurazepam and placebo as hypnotic agents in pre surgical patients. PMID- 4214671 TI - Triazolam: a new benzodiazepine hypnotic and its effect on mood. PMID- 4214672 TI - A transcultural study with clomacran: comparison of two assessment methods. PMID- 4214673 TI - Comparison of thiopropazate and trifluoperazine on oral dyskinesia - a double blind study. PMID- 4214674 TI - A double-blind comparison of pimozide and chlorpromazine in the maintenance care of chronic schizophrenic outpatients. PMID- 4214675 TI - Sex-chromosome replication in blood cells of XX-XY chimeric marmosets. PMID- 4214676 TI - Serum protein paper electrophoresis in cystic fibrosis correlated with bacteriological lung findings. PMID- 4214677 TI - Restoration of regional wall motion by nitroglycerin therapy in patients with left ventricular asynergy. PMID- 4214678 TI - Pulmonary monosporosis: report of a case with precipitating antibody. PMID- 4214679 TI - Experimental study for rapid sterilization of the flexible fiberoptic bronchoscope. PMID- 4214680 TI - [Gastrointestinal locations of Recklinghausen's disease. Apropos of a case]. PMID- 4214681 TI - Spontaneous chromosome rearrangements in an established cell line of Drosophila melanogaster. PMID- 4214682 TI - Initial phases of DNA synthesis in Drosophila melanogaster. I. Differential participation in replication of the X chromosomes in males and females. PMID- 4214683 TI - Replicating DNA molecules from fertilized eggs of Cochliomyia hominivorax (Diptera). PMID- 4214684 TI - [Sedimentation and density characteristics of ribosomes from Euglena gracilis chloroplasts]. PMID- 4214685 TI - [Paths of photosynthetic assimilation of carbon dioxide in Spirulina]. PMID- 4214686 TI - [Kinetic properties of rabbit skeletal muscle glycogen synthetase]. PMID- 4214687 TI - The metabolic fate of cyclophosphamide. PMID- 4214688 TI - [X-ray evaluation of the total prosthesis in hip-joint replacement and its complications]. PMID- 4214689 TI - [Immune antibodies and acute renal failure (author's transl)]. PMID- 4214690 TI - [Letter: Erysipelas]. PMID- 4214691 TI - [The sterilizing capacity of the micro-Harvey hotgas-pressure sterilizer]. PMID- 4214692 TI - An assay for growth hormone and prolactin-releasing activities using a bovine pituitary cell culture system. PMID- 4214693 TI - In vivo effects of prostaglandins on TRH-induced TSH secretion. PMID- 4214694 TI - Effect of catecholamines on the TRH-stimulated release of prolactin and growth hormone from sheep pituitaries in vitro. PMID- 4214695 TI - The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study. PMID- 4214696 TI - The effect of subpial vertical cortical incisions on a cobalt-gelatin focus. PMID- 4214697 TI - Circulatory and respiratory changes in spontaneous epileptic seizures in man. PMID- 4214698 TI - Dispersion pattern of visual evoked responses in epilepsy. PMID- 4214699 TI - Optimal antibiotic therapy for infections in patients with cancer: prospects for the future. PMID- 4214700 TI - Changing patterns of infection in cancer patients. PMID- 4214701 TI - Administration of carbenicillin and ticarcillin--pharmaceutical aspects. PMID- 4214702 TI - Antipseudomonal drugs: comparative study of gentamicin, sisomicin and tobramycin in vitro and in human volunteers. PMID- 4214703 TI - The dynamic state of the macrophage plasma membrane. Attachment and fate of immunoglobulin, antigen and lectins. PMID- 4214704 TI - An allotypic marker on chicken immunoglobulin M. PMID- 4214705 TI - Interference of oral immunization with the intestinal absorption of heterologous albumin. PMID- 4214706 TI - Inhibition of mitogenic stimulation of mouse lymphocytes by anti-mouse immunoglobulin antibodies. I. Mode of action. PMID- 4214707 TI - IgD and IgM on the membrane of lymphoid cells in macroglobulinemia. Evidence for identity of membrane IgD and IgM antibody activity in a case with anti-IgG receptors. PMID- 4214708 TI - The in vivo effects of concanavalin A on the cellular immune response in BALB-c mice. Inhibition of the delayed hypersensitivity reaction to tuberculin. PMID- 4214709 TI - Membrane 32P-phospholipid labeling in early developing toad embryos. PMID- 4214710 TI - Ontogeny and localization of gamma-crystallins in Rana temporaria, Ambystoma mexicanum and Pleurodeles waltlii normal lens development. PMID- 4214711 TI - Schistosoma mansoni: mechanism of cercarial tail loss and its significance to host penetration. PMID- 4214712 TI - Trypanosoma cruzi: morphogenesis in diffusion chambers in the mouse peritoneal cavity and attempted stimulation of host immunity. PMID- 4214713 TI - The amino acid sequence and predicted structure of Streptomyces griseus protease A. PMID- 4214714 TI - Biogenic amine specificity of cortical peptide synthesis in monkey brain. PMID- 4214715 TI - Immobilization of ligands for biospecific affinity chromatography via their hydroxyl groups. The cyclohexaamylose-beta-amylase system. PMID- 4214716 TI - The correlation between the apparent molecular weight and the enzymic activity of lactose synthetase. PMID- 4214717 TI - Precipitating antibodies directed against soluble elastin - the basis of a sensitive assay. PMID- 4214718 TI - Glycollate formation and excretion by the purple photosynthetic bacterium Rhodospirillum rubrum. PMID- 4214719 TI - Transformation of organic compounds by microbial enzymes. PMID- 4214720 TI - The surfactant system of the lung. PMID- 4214721 TI - Clinically useful antibiotics obtained by directed chemical modification lincomycins. PMID- 4214722 TI - [Relation between contractile parameters and sodium and potassium ion distribution in vertebrate skeletal muscles]. PMID- 4214723 TI - The synthesis and activity of tyrosinase during development of the frog Rana pipiens. PMID- 4214724 TI - Transcriptionally dependent accumulation of tyrosinase polyribosomes during frog embryonic development and its relationship to neural plate induction. PMID- 4214725 TI - Esophagoscopy as a source of Pseudomonas aeruginosa sepsis in patients with acute leukemia: the need for sterilization of endoscopes. PMID- 4214726 TI - Role of oral intake in maintenance of gut mass and disaccharide activity. PMID- 4214727 TI - Kaposi's sarcoma presenting with diarrhea and protein-losing enteropathy. PMID- 4214728 TI - Role of lysosomes in carrageenan-induced cecal ulceration. PMID- 4214729 TI - Adenine nucleotide metabolism in regenerative, atrophic, and necrotizing processes of the liver. PMID- 4214730 TI - Effect of TSH and long-acting thyroid stimulator on thyroid 131I-metabolism and metamorphosis of the Mexican axolotl (Ambystoma mexicanum). PMID- 4214731 TI - The role of TRH in the neoteny of the Mexican axolotl (Ambystoma mexicanum). PMID- 4214732 TI - Effect of glucose on vanillic acid oxidation in Cellulomonas sp. PMID- 4214733 TI - D-amino acids in the cell pool of bacteria. PMID- 4214734 TI - Changes in the level and character of colostral immunoglobulins during the lactation period in sows. PMID- 4214735 TI - Distribution of interindividual distances in patas monkeys and gelada baboons. Species and sex differences. PMID- 4214736 TI - Activity patterns of red colobus (Colobus badius tephrosceles). PMID- 4214737 TI - Ecology and population dynamics of Colobus guereza in Ethiopia. PMID- 4214738 TI - An analysis of subgroup structure and process in a captive squirrel monkey (Saimiri sciureus) colony. PMID- 4214739 TI - The behavioral repertoire of the squirrel monkey (Saimiri). PMID- 4214740 TI - Visual acuity as a function of wavelength in three Catarrhine species. PMID- 4214741 TI - Aflatoxins and sterigmatocystins. PMID- 4214742 TI - The antibiotic complex of the verrucarins and roridins. PMID- 4214743 TI - Evidence that glyburide-induced diuresis is not mediated by inhibition of ADH. PMID- 4214744 TI - Influence of Ca2 ions on the activity of human liver glutamate dehydrogenase. PMID- 4214745 TI - Purification and some properties of a heat labile serum factor (UP); identity with glycine-rich beta-glycoprotein and properdin factor B. PMID- 4214746 TI - [Partial purification and properties of glycyl-L-leucine hydrolase (EC 3.4.3.2) from human milk]. PMID- 4214747 TI - [On the determination of the biological value of dietary proteins, XVII. The biological value of different amino acid solutions after oral and parenteral application]. PMID- 4214748 TI - A combination of micro-disc electrophoresis with antigen-antibody crossed electrophoresis. Identification and quantitative determination of individual serumproteins. PMID- 4214749 TI - [The phospholipid dependence, enrichment and characterization of microsomal 17beta-hydroxysteroid-oxido reductase and "transhydrogenase activity" from human placenta (author's transl)]. PMID- 4214750 TI - [Subtilin, II: the amino acid composition of subtilin (author's transl)]. PMID- 4214751 TI - [Subtilin, III: enzymatic fragmentation with trypsin and thermolysin (author's transl)]. PMID- 4214752 TI - [Subtilin, V: sequence and assignment of the sulfide bridges in the heterodetic tricyclic peptide of the amino acid residues 3-19 (author's transl)]. PMID- 4214753 TI - The suitability of lipase from Rhizopus arrhizus delemar for analysis of fatty acid distribution in dihexosyl diglycerides, phospholipids and plant sulfolipids. PMID- 4214754 TI - The amino acid sequences of the alpha and beta polypeptide chains of adult hemoglobin of the savannah monkey (Cereopithecus aethiops). PMID- 4214755 TI - The chemical modification of peptide antibiotics. Part II. The relative roles of ethanolamine and indole groupings in the biological activity of gramicidin. PMID- 4214756 TI - Reassociation of IgM subunits in the presence and absence of J chain. PMID- 4214757 TI - Carcinoembryonic antigen (CEA): activity of meconium and normal colon extracts. PMID- 4214758 TI - Cryoproteins in acute serum sickness: correlations between antigen cryoprecipitation, immune complexes and immune elimination in acute experimental serum sickness. PMID- 4214759 TI - IgA as a blocking factor in human malignant melanoma. PMID- 4214760 TI - Immunosuppressive activity of mouse amniotic fluid. PMID- 4214761 TI - Bypass-activation of the complement system starting with C3. I. Generation and function of an enzyme from a factor of guinea-pig serum and cobra venom. PMID- 4214762 TI - Intestinal secretion of immunoglobulins in the preruminant calf. PMID- 4214763 TI - The influence of preparturient intramammary vaccination on immunoglobulin levels in bovine mammary secretions. PMID- 4214764 TI - IgG heavy chain sub-classes in mixed cryoglobulins. PMID- 4214765 TI - Angiokeratoma. PMID- 4214766 TI - Studies on Pseudomonas biomass obtained from petroleum fractions. PMID- 4214767 TI - Mental retardation in children. III. Tay-Sachs disease and infantile lipid storage disorders with visceral involvement. PMID- 4214768 TI - Local antibody production in experimental pyelonephritis: amount, avidity, and immunoglobulin class. AB - LOCAL ANTIBODY FORMATION IN INFECTED RABBIT KIDNEYS WAS STUDIED WITH THREE TECHNIQUES: the ammonium sulfate precipitation technique, the enzyme-linked immunosorbent assay, and by binding of newly synthesized (14)C-labeled antibodies to heat-killed bacteria. Local antibody was detected by day 11 of infection with all three techniques, and a significant correlation was found in titers by all three methods. In these studies, antibody synthesized early was in IgG and IgA class, whereas IgM antibodies appeared later (day 20) in the antibody response. No maturation of avidity of local antibody was noted with time. Since it was necessary to use different animals at each test occasion, individual differences in avidity could account for failure to note an increase in avidity with time. PMID- 4214769 TI - Virulence and the role of iron in Pseudomonas aeruginosa infection. AB - The virulence of Pseudomonas aeruginosa can be enhanced by passage in mice or rabbits. Enhanced virulence has some specificity for the host in which the passage is done. Experimental infection in the peritoneal cavity of cannulated rabbits has shown that the injection of iron compounds can lead to a rapid and fatal growth of an otherwise nonlethal dose of bacteria. In vitro the unsaturated iron-binding proteins present in the peritoneal fluid can halve the growth rate of P. aeruginosa. The restricted rate of growth is restored to normal if the iron binding proteins are saturated with iron. Exactly the same results are achieved with purified transferrin. Both fatal and nonfatal infections with P. aeruginosa cause a sharp fall in the percentage of saturation with Fe of the plasma and peritoneal fluid. In both normal and infected animals the peritoneal fluid is invariably less saturated than the plasma. Specific antiserum not only protects against death but also against the fall in iron saturation of the plasma and peritoneal fluid. In both fatal and nonfatal infections a high proportion of viable bacteria are unphagocytized in the peritoneal cavity. PMID- 4214770 TI - Local antibody production against the murine toxin of Yersinia pestis in a golf ball-induced granuloma. AB - The method of Garra and Baygorria, for localized antibody production, has been adapted for obtaining high-titered and monospecific antibodies against the murine toxin of Yersinia pestis. A hollow, perforated plastic golf ball surgically implanted under the skin of rabbits induced the formation of a granuloma. When the murine toxin of Y. pestis was injected directly into the granulomatous cavity, an increased amount of antibody was found in the granuloma fluid as compared with serum or with serum antibody obtained by conventional immunization. The granuloma antibody consisted mainly of immunoglobulin G, probably produced locally by lymphoid cells of the granuloma. The immune granuloma fluid and the granuloma tissue were rich in plasma cells and lymphocytes. The chemical composition of the granuloma fluid indicated that it was a transudate. PMID- 4214771 TI - Lipid metabolism of monkey kidney cells (LLC-MK-2) infected with Chlamydia trachomatis strain lymphogranuloma venereum. AB - Lipid metabolism of monkey kidney (LLC-MK-2) cells and cells infected with a Chlamydia trachomatis strain lymphogranuloma venereum (LGV) was studied. The protein-to-lipid ratio of normal MK-2 cells was found to increase linearly over a 60-h period of incubation. The protein-to-lipid ratio of the infected cells was similar to that in normal cells until 36 h after infection, when a plateau in the ratio was observed. Lipid synthesis of the infected cells was found to be inhibited after 48 h of infection. Turnover of host lipids did not appear to be markedly altered by infection with LGV over a 48-h period of incubation. An anteiso branched chain of 15:0 fatty acid was found in infected cells but not in normal cells. The appearance of this fatty acid, correlated with a rise in the infectivity of LGV, suggests that synthesis of specific lipids was associated with the infection. PMID- 4214772 TI - Growth inhibition among strains of Neisseria gonorrhoeae due to production of inhibitory free fatty acids and lysophosphatidylethanolamine: absence of bacteriocins. AB - Each of 50 tested strains of Neisseria gonorrhoeae produced growth-inhibitory substances that were active against most strains of gonococci or meningococci, but not against species other than the Neisseria. There were quantitative differences among different strains in production of the inhibitor and sensitivity to it, but not of sufficient magnitude to permit routine strain typing. The inhibitor was associated with the cell pellet (crude cell envelope) and was not inducible with mitomycin C. Inhibitory activity was thermostable and resisted alkali and proteolytic enzymes. The inhibitor was quantitatively recovered from whole cells by chloroform-methanol extraction. Separation of total gonococcal lipids by silica gel chromatography revealed inhibitory activity in both the free fatty acid and the phospholipid fractions. The major phospholipid, phosphatidylethanolamine, had no inhibitory activity, but monoacyl phosphatidylethanolamine, a minor phospholipid, was quite inhibitory. It is likely that the "bacteriocin" of N. gonorrhoeae strains results from the degradation of phosphatidylethanolamine to inhibitory long-chain free fatty acids and monoacyl phosphatidylethanolamine. PMID- 4214773 TI - Inflammatory lymphocyte in cell-mediated antibacterial immunity: factors governing the accumulation of mediator T cells in peritoneal exudates. AB - The lymphocytes which mediate immunity to infection with Listeria monocytogenes in the mouse accumulated in casein-induced peritoneal exudates. They were T cells, as evidenced by their susceptibility to anti-theta serum, but some were also destroyed by anti-immunoglobulin serum. For a given number of cells, exudate cells were at least six times more efficient than spleen cells in protecting normal recipients against lethal challenge. The extent to which mediator cells accumulated in exudates was found to be governed by the level of their production in responding lymphoid tissue and by the time available for them to migrate into an exudate. An intraperitoneal injection of casein at any stage of infection resulted in a progressive accumulation of mediator cells that continued for 3 days. The accumulation was not caused by continuous entry of cells during the whole of this period, but resulted from division of a limited number of cells that entered during the first 24 h. Accumulation of mediator cells in an exudate was associated with the conversion of a population of dividing cells into a population of nondividing T cells with a relatively short life-span. PMID- 4214774 TI - Inhibition of Pseudomonas aeruginosa by hyperbaric oxygen: interaction with mouse peritoneal exudate cells. AB - High-pressure oxygen (HPO) therapy for Pseudomonas aeruginosa infections of burn wounds has not been as effective as in vitro studies predicted. Mitigation of HPO toxicity for P. aeruginosa by nutrients present at the burn site could explain the lack of in vivo success. Alternatively, HPO-induced depression of host defense mechanisms could negate beneficial effects arising from HPOs known toxicity for P. aeruginosa. Accordingly, mouse peritoneal exudate cells (PEC), preincubated for 24 h in 1 atm of air-CO(2), were used to study the in vitro effects of HPO or air-CO(2) on phagocytosis of P. aeruginosa or sheep erythrocytes (SRBC). Subsequent 2-h exposures of PEC to increasing numbers of bacteria, in an air-CO(2) atmosphere, decreased the percentage of bacteria cleared as well as PEC viability. Similar exposures of PEC to bacteria in an HPO atmosphere prevented the loss of PEC viability and increased bacterial clearance. In control experiments, increasing the number of SRBC relative to PEC decreased the percentage of SRBC cleared without decreasing PEC viability, as determined under air-CO(2); short (2 h) exposure to HPO did not affect SRBC clearance. Microscopic examination of PEC indicated that a 24-h preincubation in HPO decreased the percentage of PEC which could ingest SRBC during subsequent experimental exposures (2 h) to air-CO(2) or HPO. These data suggest that short periods of exposure to HPO promote the ability of PEC to clear pseudomonads by adversely affecting the bacteria. This in turn prevents a pseudomonad-induced depression of PEC viability and function. In contrast, prolonged HPO exposure may be detrimental to phagocytic activity. PMID- 4214775 TI - Protein fraction with immunogenic potential and low toxicity isolated from the cell wall of Neisseria meningitidis group B. AB - Several fractions were extracted from the cell envelope (CE) of Neisseria meningitidis group B and characterized with regard to their morphology, antigenicity, protein composition, and toxicity. Whole bacterial cells were suspended in a medium of low ionic strength and disrupted in a French pressure cell. The crude CE thus obtained were separated into cell membrane (CM) enriched and cell wall (CW) enriched fractions on sucrose density gradients. In addition, CM and CW fractions were separated from CE on the basis of differential solubility in the nonionic detergent, Triton X-100. The Triton-insoluble fraction, containing primarily CW components, was further treated with a mixture of Triton and ethylenediaminetetraacetic acid, which was shown to remove additional protein and most of the lipopolysaccharide. Electron microscope examination of the various fractions revealed typical unit membrane structures in the case of CM, or large, open segments in the case of CW. The Triton-insoluble and especially the Triton-ethylenediaminetetraacetic acid-insoluble fractions consisted of small vesicular structures. All fractions, except the Triton-soluble fraction, when assayed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, were shown to contain one major protein component accounting for more than 50% of the total. Sera from rabbits immunized with the various fractions formed precipitin lines in immunodiffusion tests against the homologous and some of the heterologous fractions. High-titer bactericidal antibodies were also demonstrated in these sera when tested against the homologous strains. Toxicity studies in rats sensitized with lead acetate indicate that the level of contamination of Triton-insoluble/Triton-ethylenediaminetetraacetic acid insoluble fractions with lipopolysaccharide was significantly smaller than that of the other fractions. PMID- 4214776 TI - Studies on gonococcus infection. V. Observations on in vitro interactions of gonococci and human neutrophils. AB - The association of in vitro human leukocytes with pilated, type 2 Neisseria gonorrhoeae exceeds that for nonpilated, type 4 organisms but is less than that for nonpilated, type 4(*) gonococci. The two nonpilated forms of gonococci (types 4 and 4(*)) attach to tissue culture cells to a much lesser extent than do pilated, type 2 organisms of the same strain. Trypsin treatment of either pilated (type 2) or nonpilated (type 4(*)) gonococci markedly reduces the attachment ingestion of these organisms with leukocytes, but the same trypsin treatment does not depilate the type 2 organisms nor visibly alter the morphology of their pili. Similar reductions in association with leukocytes are found if the gonococci are pretreated with chymotrypsin, heat, or glutaraldehyde. High levels of association between gonococci and leukocytes are reestablished if the trypsin or chymotrypsin treated organisms are reincubated in protease-free medium. These data suggest that interactions between gonococci and human neutrophils are mediated through surface characteristics of the bacteria, different from those which influence attachment of the organisms to tissue culture cells. In the latter instance, pili appear to positively influence gonococcal attachment, whereas in the former a nonpilus bacterial cell wall nonpilus protein is probably the major determiner in the interaction between leukocytes and gonococci. PMID- 4214777 TI - Studies on gonococcus infection. VI. Electron microscopic study on in vitro phagocytosis of gonococci by human leukocytes. AB - The ingestion of Neisseria gonorrhoeae by isolated human leukocytes in vitro has been studied by electron microscopy. Use of the modified critical-point drying method allows clear visualization of progressive ingestion of both pilated and nonpilated gonococci by leukocytes. Incomplete ingestion of pilated gonococci with protrusion of tangled masses of pili from sites of phagocytosis are also found. PMID- 4214778 TI - Characterization of plasmid deoxyribonucleic acid from Neisseria gonorrhoeae. AB - Five of six independent gonococcal isolates have been found to harbor a plasmid pool of covalently closed-circular deoxyribonucleic acid about 2.4 x 10(6) daltons in size. The plasmid species were 0.5-mol fraction of guanine plus cytosine and comprised 6 to 8% of the total gonococcal deoxyribonucleic acid equivalent, to approximately 24 to 32 copies per cell. There was no apparent correlation between the presence of these plasmid species and the in vitro clonal variation of gonococci associated with the loss of pili. PMID- 4214779 TI - Synergistic action of cord factor and mycobacterial sulfatides on mitochondria. AB - The mechanism of a synergistic toxicity of 6,6'-dimycoloyl-alpha,alpha'-d trehalose (cord factor) and 2,3,6,6'-tetraacyl-alpha,alpha'-d-trehalose 2' sulfate (sulfolipid I) for mice was studied. Sulfolipid I was entirely nontoxic, but it markedly accelerated the lethal toxicity of cord factor for mice. In vivo, sulfolipid I affected neither respiration nor accompanying phosphorylation of mouse liver mitochondria, whereas in vitro, it induced a swelling and disruption of mitochondrial membranes and strongly inhibited mitochondrial oxidative phosphorylation. The effect of sulfolipid I on mitochondrial structure and function in vitro was neutralized by bovine serum albumin and various animal sera, whereas that of cord factor and cord factor plus sulfolipid I was not prevented by bovine serum albumin. The simultaneous injection of cord factor and sulfolipid I caused an intensive fragmentation of mitochondria and a marked decrease in respiratory and phosphorylative activity in mitochondria. These data indicate that sulfolipid I can achieve an effective attack on mitochondria in combination with cord factor in vivo and induces heavier damage in mitochondrial structure and function than that produced by cord factor alone. PMID- 4214780 TI - Strain virulence and the lysosomal response in macrophages infected with Mycobacterium tuberculosis. AB - Strains H37Ra and H37Rv, attenuated and virulent variants, respectively, of the original human strain H37 of Mycobacterium tuberculosis, were used to infect cultures of mouse peritoneal macrophages. Bacterial viability of each strain was assessed over a 2-week period, and the cellular response to H37Ra during the first week was observed using electron microscopy. Prelabeling of secondary lysosomes with ferritin was used to facilitate the estimation of fusion of the lysosomes with phagosomes containing the bacteria. Streptomycin was excluded from the medium of cell cultures infected with H37Ra. The intracellular viability of strain H37Rv (in the presence of streptomycin) showed a lag during the first week after infection and then rose progressively to a mean figure seven times the starting level. In contrast, the viability of strain H37Ra declined, on the average, to one-fifth of the starting level during the first week; moreover, this decline occurred in the absence of antibiotics. In the second week a variable rise in the viable count took place, usually regaining the starting level. Electron microscopy of macrophages infected with H37Ra revealed a higher proportion of "damaged" bacteria 5 days after infection than at 1 day, in keeping with the decline in viability. Phagosomes containing these "damaged" (and presumed dead) organisms showed virtually universal fusion with prelabeled lysosomes. Phagosomes containing "intact" bacteria of this strain showed a prevalence of fusion varying from 38 to 56%, somewhat higher than the level previously reported for "intact" organisms of H37Rv. Nevertheless, the lysosome phagosome fusion response to "intact" H37Ra was still far less extensive than that observed previously towards "intact" M. lepraemurium (around 90%). In conclusion, a difference between the macrophage lysosome-phagosome fusion response towards viable organisms of strain H37Ra and to the virulent strain H37Rv was observed, but was not pronounced, and the present findings are in keeping with the increasingly held view that H37Ra should be regarded as a low virulence or attenuated strain rather than truly avirulent. PMID- 4214781 TI - Purification and some properties of progenitor toxins of Clostridium botulinum type B. AB - Purification of progenitor toxin of Clostridium botulinum type B strain Okra was undertaken by sequential steps of acid precipitation, extraction, ammonium sulfate precipitation, ribonuclease digestion, acid precipitation, protamine treatment, sulphopropyl-Sephadex chromatography, and Sephadex G-200 gel filtration. Two different molecular-sized toxins, named large (L) and medium (M) toxins, were obtained. L toxin was centrifugally homogeneous but electrophoretically heterogeneous. It contained 2.5 x 10(8) to 3.0 x 10(8) mean lethal doses per mg of nitrogen, and its sedimentation constant was 16S. M toxin was centrifugally and electrophoretically homogeneous. It contained 5.5 x 10(8) to 6.0 x 10(8) mean lethal doses per mg of nitrogen, and its sedimentation constant was 12S. The presence of both L and M toxins in spent culture was demonstrated. It seems justified, therefore, to call both progenitor toxins. Both consisted of toxic and nontoxic components. The toxic components of L and M toxins appeared to be identical with each other. The nontoxic component of L toxin was 12S and possessed a hemagglutinin activity of about 0.5% that of type A crystalline toxin; that of M toxin was 7S and possessed no hemagglutinin activity. They were antigenically related but not identical. PMID- 4214782 TI - Cellular immune activity of a galactomannan-protein complex from mycelia of Histoplasma capsulatum. AB - A galactomannan-protein complex was extracted from defatted mycelium of Histoplasma capsulatum with 0.25 N alkali at 25 C. It accounted for 7.5% of the cell dry weight in nondialyzable form and had a galactose-mannose ratio of 2:5. The complex containing 68% protein was separated into polysaccharide and glycoprotein components by ion-exchange chromatography. The galactomannan formed a single precipitate in immunodiffusion, sharing a common antigen with the glycoprotein which contained two precipitating antigens. The glycoprotein elicited delayed-type hypersensitivity in guinea pigs as measured by skin-test and macrophage migration inhibitory factor assay, with 5 mug resulting in 86% specific inhibition. The galactomannan was skin-test negative, but 10 mug resulted in 80% specific inhibition of migration. PMID- 4214783 TI - Role of interferon in six cell lines persistently infected with rubella virus. AB - Presistent infections with rubella virus were established in baby hamster kidney, BSC-1, HeLa, RK-13, rabbit embryo chondrocyte, and Vero cell lines. All of the cultures except Vero continually produced rubella virus and interferon to which the virus was sensitive. Concurrently, only the Vero cells did not display interference against superinfection with Newcastle disease and vesicular stomatitis viruses. The addition of 1,000 U of exogenous interferon to the cultures cured only the rabbit embryo and Vero cells of the persistent infection. That the interferon is not required for the initiation and maintenance of rubella viral persistence in vitro is implied by the following. (1) Vero cells were persistently infected in the absence of interferon; (2) actinomycin D or cortisone inhibited interferon synthesis but not the rubella viral infection; and (3) cells continuously cultured in the presence of cortisone maintained a viral persistence without interferon synthesis. On the other hand, interferon seems to be responsible for the viral interference; Vero cells infected with rubella virus and cultures inoculated with rubella virus in the presence of actinomycin D or cortisone did not display interference against Newcastle disease or vesicular stomatitis viruses. PMID- 4214784 TI - Growth of typhoid and paratyphoid bacilli in intravenously infected mice. AB - The in vivo growth of Salmonella paratyphi A, S. paratyphi B, S. paratyphi C, and S. typhi, as well as of an S. typhi-typhimurium hybrid, was studied in three different strains of mice. S. paratyphi A and B and S. typhi demonstrated very little growth potential in any of the intravenously infected mice, even after as many as 20 serial mouse passages. It was noted, however, that small numbers of viable S. paratyphi B and S. typhi persisted in the spleens of infected mice for up to 28 days. Salmonella paratyphi C and the S. typhi-typhimurium hybrid gave rise to progressive systemic infections beginning from very small intravenous inocula. The median lethal doses for the C57B1 strain of mouse were about five organisms. The relevance of these findings with regard to the development of an animal model for studying human typhoid fever vaccines is discussed. PMID- 4214785 TI - Demonstration of the phenomena of microbial persistence and reversion with bacterial L-forms in human embryonic kidney cells. AB - A series of experiments was undertaken in which human embryonic kidney (HEK) fibroblasts were infected with either relatively stable or stable L-forms of Streptococcus faecalis. The infected cells were maintained by splitting over long periods (1 to 2 months) while samples were withdrawn for culture and electron microscopic studies. Relatively stable S. faecalis L-forms could be cultured from infected cells only during the first week after infection, although L-form-like material was frequently detected at later periods by electron microscopy. HEK cells continued to proliferate and showed no gross histopathology until reversion occurred. At reversion, electron microscopy revealed the presence of intracellular L-forms, transitional variants, and intra- and extracellular bacterial forms. Unlike relatively stable L-forms, stable L-forms were culturable throughout the experimental period. These experiments demonstrate the phenomena of persistence and reversion in vitro. Electron microscopy indicated that the L forms entered the HEK cells, where they underwent morphological changes. Observations suggested that these altered L-forms (elementary bodies) persisted in the cell until reversion to the parent bacterial form was triggered. Infected cells, when treated with L-form antiserum and stained with fluorescein-conjugated goat anti-rabbit serum, were consistently positive regardless of cultural findings. PMID- 4214786 TI - Proposed reproductive cycle for a relatively stable L-phase variant of Streptococcus faecalis. AB - Based on electron microscopic observations, the reproductive cycle of a relatively stable L-phase variant of Streptococcus faecalis was proposed. The small, dense, nonvesiculated L-form is envisioned as the central (core) element. It was seen to divide and bud rapidly. In addition, the dense forms appeared to be capable of growth and development within vesicles of mature mother forms. When these forms were released from the vesicles into the surrounding fluid medium, further growth occurred, resulting in the development of immature and ultimately mature mother forms. Under conditions unfavorable for L-form growth, these dense forms developed first into transitional forms and then into the bacterial form. These dense forms might therefore be considered as undifferentiated "stem cells' with the capacity to develop along several different routes, depending upon the stimulus received. PMID- 4214787 TI - In vitro antilisterial activity of soluble product(s) released from Listeria immune murine peritoneal macrophages. AB - The importance of macrophages as effector cells in cellular reactions of immunity and hypersensitivity is well established (8). Macrophages activated as a result of specific immunological events exhibit increased microbicidal activity not only for the primary organism used for immunization purposes but also against unrelated intracellular pathogens (7). It is believed that the acquisition of this bactericidal or bacteriostatic activity is conferred on macrophages by materials released during the interaction of specifically immune lymphocytes with the antigen (Fowles et al., 1973; Godal et al., 1971; Jones and Youmans, 1973; Krahenbuhl and Remington, 1971; Mackaness, 1971; Patterson and Youmans, 1970). The antimicrobial activity in these studies refers to the intracellular inhibition and/or killing of the organisms; no attempts were made to assess the effect of activated macrophages on the extracellularly residing organisms. In an earlier study with the pathogenic yeastlike fungus Cryptococcus neoformans, we observed that freshly collected peritoneal macrophages from mice pretreated with a variety of nonspecific agents or from specifically immune mice possessed the capacity to exert anti-cryptococcal effect both on intracellular yeasts as well as those present in the extracellular milieu (Sethi et al., 1971; Sethi and Pelster, in press). Our results suggest that soluble product(s) released from mouse macrophages immune to Listeria monocytogenes can exert antilisterial activity under in vitro conditions. PMID- 4214788 TI - The microbial decomposition of dental resins and its importance to the microbial balance of the oral cavity. PMID- 4214789 TI - Bursal and postbursal cells in chicken: age-dependence of germinal center formation in spleen. PMID- 4214790 TI - Application of in vitro and in vivo assay techniques in the isolation of rye grass (Lolium perenne) pollen allergens. PMID- 4214791 TI - [Gentamicin concentrations in tissues and body fluids of various animals]. PMID- 4214792 TI - Serum histaminase in leprosy. PMID- 4214793 TI - New methods for surface ultrastructure: Comparative studies of scanning electron microscopy, transmission electron microscopy and replica method. PMID- 4214794 TI - The in vivo distribution of 51Cr-labeled Trypanosoma cruzi in mice. PMID- 4214795 TI - Autoimmunity in trypanosome infections. II. Anti-fibrin-fibrinogen (anti-F) autoantibody in Trypanosoma (Trypanozoon) brucei infections of the rabbit. PMID- 4214797 TI - Host dietary changes and the hindgut fauna of cockroaches. PMID- 4214796 TI - [In vitro study of immunologic phenomena in humain and experimental schistosomiasis. I. Comparative in vitro study of the lethal activity of immune serums on the immature and adult forms of Schistosma mansoni]. PMID- 4214798 TI - The production of bismuth-204 for medical use. PMID- 4214799 TI - Cell-surface receptors of normal, regenerating, and cultured corneal epithelial and endothelial cells. PMID- 4214800 TI - Calcium and high molecular weight protein aggregates in bovine and human lens. PMID- 4214801 TI - Ossifying fibroma, a neoplastic entity. PMID- 4214802 TI - [A comparative clinical, radiologic, biochemical and genetic study of Sanfilippo's disease, type A and B. Six case reports]. PMID- 4214803 TI - Host factors in post-operative infections due to Pseudomonas aeruginosa. PMID- 4214804 TI - The use of quantiatative cytochemical analyses in rapid prenatal detection and somatic cell genetic studies of metabolic diseases. PMID- 4214805 TI - Procedures for clinical management of pinnipeds. PMID- 4214806 TI - Extraction and analysis of Aroclor 1254 components in blood. PMID- 4214807 TI - Applications of nuclear magnetic resonance spectroscopy to antibiotics. I. Specific identification of penicillins and cephalosporins. PMID- 4214808 TI - Gas-liquid chromatographic determination of ethylenediaminetetraacetic acid in pickled vegetables. PMID- 4214809 TI - Tobacco sensitivity in the allergic population. A specific allergic entity. PMID- 4214810 TI - Immune responses to chemically modified bacterial alpha-amylase. PMID- 4214811 TI - Immunochemical comparison of myosins from chicken cardiac, fast white, slow red, and smooth muscle. PMID- 4214812 TI - Further studies on the stability of sporulation messenger ribonucleic acid in Bacillus subtilis. PMID- 4214813 TI - GM1 ganglioside beta-galactosidase. A. Purification and studies of the enzyme from human liver. PMID- 4214814 TI - Variations in the quaternary structure of three lactic acid bacteria aldolases. Evidence for the existence of a class I and class II aldolase in Lactobacillus casei. PMID- 4214815 TI - The conformation of thermolysin. PMID- 4214816 TI - Micro cell culture method for determination of diphtheria toxin and antitoxin titres using VERO cells. I. Studies on factors affecting the toxin and antitoxin titration. PMID- 4214817 TI - Micro cell culture method for determination of diphtheria toxin and antitoxin titres using VERO cells. II. Comparison with the rabbit skin method and practical application for seroepidemiological studies. PMID- 4214818 TI - The protective effect of Pseudomonas culture filtrates against experimental infection in mice. PMID- 4214819 TI - Standardization and quality control of Leishmania tropica vaccine. PMID- 4214820 TI - A wear resistant material for total joint replacement--tissue biocompatibility of an ultra-high molecular weight (UHMW) polyethylene-graphite composite. PMID- 4214821 TI - Determination of rates of DNA synthesis in cultured mammalian cell populations. AB - In cultures of a murine mastocytoma, endogenous synthesis of thymidine phosphates, as determined by the incorporation of [(3)H]deoxyuridine into DNA, was reduced within 15 min to less than 3% of control values by the addition of amethopterin (10 microM) in combination with hypoxanthine and glycine. If [(3)H]thymidine and unlabeled thymidine were added simultaneously with amethopterin, the increase with time of radioactivity in cellular DNA was linear at least between 30 and 90 min, while radioactivity in the acid-soluble nucleotide fraction remained constant during this time interval, indicating that intracellular thymidine nucleotides had the same specific activity as exogenously supplied [(3)H]thymidine. This permitted calculation of the amount of thymidine incorporated per hour into DNA of 10(6) cells. In conjunction with the base composition of mouse DNA, these results were used to calculate rates of DNA synthesis. Cell proliferation rate, cell cycle time, and the duration of the S period were not affected to any appreciable extent by the addition of amethopterin and thymidine. Rates of DNA synthesis, as derived from thymidine incorporation rates, were in good agreement with those derived from the measured mean DNA content of exponentially multiplying cells and rates of cell proliferation. PMID- 4214823 TI - Microtubule arms and cytoplasmic streaming and microtubule bending and stretching of intertubule links in the feeding tentacle of the suctorian ciliate Tokophrya. AB - Microtubules attached to the pellicle at the tips of tentacles pivot through about 140 degrees on these attachments, splay apart, and bend along their longitudinal axes when feeding occurs. The tubules could be bending in response to pellicular contractions; active bending, sliding, or contraction of the tubules may not be involved. Intertubule links apparently prevent tubules from splaying apart at certain levels. These links are probably under tension during feeding. They stretch; they sometimes become half as thick and eight times as long as they are before feeding. Often, tubules joined together by these links also change in shape; they become slightly flattened and elliptical in cross section. Cytoplasm from the ciliate Tetrahymena is drawn down a feeding tentacle inside an invagination of the Tokophrya cell membrane from the tentacle tip. The positions of arm-bearing microtubules around such invaginations indicate that arms are involved in moving invaginations along. The edges of the perforated Tetrahymena cell membrane are "sealed" to the cell membrane of Tokophrya around each feeding tentacle tip. PMID- 4214822 TI - Action of cytochalasin D on cells of established lines. II. Cortex and microfilaments. AB - Cells in culture exposed to cytochalasin D (CD) rapidly undergo a long-sustained tonic contraction. Coincident with this contracture the thin microfilaments of the cortex become compacted into feltlike masses. The ravelled filaments of these masses remain actinlike and bind heavy meromyosin; they are not disrupted or disaggregated, but rather, appear to represent a contracted state of the microfilament apparatus of the cell cortex. On continued exposure to CD, 'myoid' bundles, containing thick, dense filaments, and larger fusiform or ribbonlike, putatively myosinoid, aggregates may appear. These appearances are interpreted as consequences of a state of hypercontraction without relaxation induced by CD. They do not occur in CD-treated cells prevented from contracting by inhibitors of energy metabolism, and are readily reversible on withdrawal of CD. Extensive ordered arrays of thin microfilaments develop in cells which are reextending during early recovery. PMID- 4214824 TI - Ciliary membrane differentiations in Tetrahymena pyriformis. Tetrahymena has four types of cilia. AB - We have examined thin sections and replicas of freeze-fractured cilia of Tetrahymena pyriformis. The ciliary necklace located at the base of all freeze fractured oral and somatic cilia has been studied in thin sections. Since electron-dense linkers have been found to connect both microtubule doublets and triplets to the ciliary membrane at the level of the necklace, the linkers and the associated necklace seem to be related to the transition region between the doublets and triplets of a cilium. Plaque structures, consisting of small rectangular patches of particles located distal to the ciliary necklace, are found in strain GL, but are absent in other strains examined in this study. In freeze-cleaved material, additional structural differentiations are observed in the distal region of the ciliary membranes of somatic and oral cilia. Somatic cilia contain many randomly distributed particles within their membrane. Oral cilia can be divided into three categories on the basis of the morphology of their freeze-fractured membranes: (a) undifferentiated cilia with very few randomly distributed particles: (b) cilia with particles arranged in parallel longitudinal rows spaced at intervals of 810-1080 A that are located on one side of the cilium; and (c) cilia with patches of particles arranged in short rows oriented obliquely to the main axis of the cilium. The latter particles, found on one side of the cilium, seem to serve as attachment sites for bristles 375-750 A long and 100 A wide which extend into the surrounding medium. The particles with bristles are located at the tips of cilia in the outermost membranelle and may be used to detect food particles and/or to modify currents in the oral region so that food particles are propelled more efficiently into the buccal cavity. Examination of thin-sectioned material indicates that the particles in oral cilia which form the longitudinal rows could be linked to microtubule doublets. Linkage between microtubule doublets and adjacent membrane areas on one side of the cilium could modify the form of ciliary beat by restricting the sliding of the microtubules. It is suggested that membrane-microtubule interactions may form the basis for the various forms of ciliary beat observed in different organisms. PMID- 4214825 TI - Electron microscope evidence of calcium-induced exocytosis in mast cells treated with 48-80 or the ionophores A-23187 and X-537A. PMID- 4214826 TI - The effect of inhalational anaesthetics on the swimming velocity of Tetrahymena pyriformis. PMID- 4214827 TI - [Experimental parenteral nutrition via the portal vein. Technics and results]. PMID- 4214828 TI - [Intraluminal diverticulum of the duodenum. (Apropos of 2 cases)]. PMID- 4214829 TI - [Parenteral nutrition in oncology. Indications and results]. PMID- 4214830 TI - Chlorobiphenylols. Thin-layer chromatography and colour reactions of some hydroxylated chlorobiphenyls. PMID- 4214831 TI - Metabolism of 17 alpha-ethinylestradiol by human liver microsomes in vitro: aromatic hydroxylation and irreversible protein binding of metabolites. PMID- 4214832 TI - Radioimmunoassay for human antithyroglobulin antibodies. II. Determination of antigen-binding capacity. PMID- 4214833 TI - Heterogeneity of circulating growth hormone in acromegaly. PMID- 4214834 TI - Evidence for a direct effect of thyrotropin-releasing hormone (TRH) on prolactin release in humans. PMID- 4214835 TI - Skeletal metabolism and body composition in Cushing's syndrome. PMID- 4214836 TI - Sanfilippo A syndrome: sulfamidase deficiency in cultured skin fibroblasts and liver. AB - The Sanfilippo A syndrome is an autosomal recessive mucopolysaccharidosis characterized clinically by severe mental retardation and biochemically by storage in tissue and excretion in urine of excessive amounts of heparan sulfate. Since sulfamide groups are present in heparan sulfate, a sulfamidase deficiency could explain the impaired degradation of this polysaccharide. To investigate the enzymic basis of this disease, assays for sulfamidase were performed. Extracts of cultured fibroblasts and post-mortem liver were prepared by suspension of tissues in acetate: NaCl buffer, pH 4.5, containing Triton X-100 (Rohm and Haas Co., Philadelphia, Pa.), sonication, and centrifugation at 10,000 g. The supernatant fluid was incubated with [(35)S]-N-sulfated heparin. The release of inorganic sulfate after 18 h of incubation was determined by chromatography on Sephadex G 25. The liver and fibroblast extracts of patients with the Sanfilippo A syndrome showed a deficiency of sulfamidase. The quantity of heparan sulfate in fibroblasts derived from patients with Sanfilippo A, Hurler's and Hunter's diseases was found to be 7-10%, while it was about 1.25% of the total glycosaminoglycans in fibroblasts of normal controls. PMID- 4214837 TI - Hyperresponse to thyrotropin-releasing hormone accompanying small decreases in serum thyroid hormone concentrations. AB - To determine whether pituitary thyrotropin (TSH) responsiveness to thyrotropin releasing hormone (TRH) is enhanced by small decreases in serum thyroxine (T4) and triiodothyronine (T3), 12 euthyroid volunteers were given 190 mg iodide po daily for 10 days to inhibit T4 and T3 release from the thyroid. Basal serum T4, T3, and TSH concentrations and the serum T4 and TSH responses to 400 mug TRH i.v. were assessed before and at the end of iodide administration. Iodide induced small but highly significant decreases in basal serum T4 (8.0+/-1.6 vs. 6.6+/-1.7 mug/100 ml; mean +/- SD) and T3 (128+/-15 vs. 110+/-22 ng/100 ml) and increases in basal serum TSH (1.3+/-0.9 vs. 2.1+/-1.0 muU/ml). During iodide administration, the TSH response to TRH was significantly increased at each of seven time points up to 120 min. The maximum increment in serum TSH after TRH increased from a control mean of 8.8+/-4.1 to a mean of 13.0+/-2.8 muU/ml during iodide administration. As evidence of the inhibitory effect of iodide on hormonal release, the increment in serum T3 at 120 min after TRH was significantly lessened during iodide administration (61+/-42 vs. 33+/-24 ng/100 ml). These findings demonstrate that small acute decreases in serum T4 and T3 concentrations, resulting in values well within the normal range, are associated both with slight increases in basal TSH concentrations and pronounced increases in the TSH response to TRH. These results demonstrate that a marked sensitivity of TSH secretion and responsiveness to TRH is applicable to decreasing, as well as increasing, concentrations of thyroid hormones. PMID- 4214838 TI - Serum 'uracil plus uridine' levels in normal subjects and their possible significance. AB - A microbiological method for the assay of uracil is described. The growth of the test organism is supported by uracil and also by uridine but not by uridylic acid. The method therefore measures uracil and uridine together. The ;uracil + uridine' level, expressed as uracil, has been measured in blood from 144 normal subjects ranging in age from cord blood to the eighth decade. The mean level of 22 mu mol/l (0.25 mg%) in cord blood decreases to 15 mumol/l (0.17 mg%) in adults over the age of 20. There is no difference between the sexes. Uracil is of interest because (a) it is a constituent base of RNA, (b) it is the precursor of two of the bases thymine and cytosine that enter into the composition of DNA, and (c) under certain circumstances it has mutagenic properties. The last is dependent upon the existence of two tautomeric forms of uracil, the common keto form which pairs normally with adenine and the rare enol form which pairs with guanine. A mistake in base pairing which allows uracil in its enol form to enter the DNA molecule and pair with guanine can result in a G = C --> A = T base transition in the DNA molecule. The molecular mechanism involved as well as the possible bearing on somatic mutation are discussed. PMID- 4214839 TI - Comparative activity of ampicillin and seven cephalosporins against group D streptococci. AB - Minimum inhibitory concentrations have been determined for ampicillin and seven cephalosporins against 93 strains of group D streptococci isolated recently from clinical material. Ampicillin was much the most active compound (modal MIC = 1.6 mug/ml); cephaloridine, cephacetrile, and cefazolin had a modal MIC of 25 mug/ml, while corresponding figures for cephalothin, cephradine, cephalexin, and cefoxitin were 50, 100, 200, and 800 mug/ml, respectively. Thus, none of the newer cephalosporins is an improvement in respect to activity against enterococci over existing compounds, and ampicillin remains overwhelmingly the beta-lactam antibiotic of choice for the treatment of infections by such organisms. Pharmacokinetic considerations, however, indicate that certain cephalosporins, for instance, cephaloridine, cefazolin, and cephanone, may be worthy of further study in view of possible synergy with aminoglycoside antibiotics. PMID- 4214840 TI - Antibodies to Candida albicans in hospital patients with and without spinal injury and in normal men and women. AB - The presence of serum agglutinins and precipitins to Candida albicans in men and women who had impaired bladder function following spinal injury is compared with that in other patients in hospital and in apparently fit men and women. Antibody levels which have commonly been regarded as significant were found in 35 of 76 patients who had urinary candidiasis; in 10 of 52 patients who had spinal injury without urinary candidiasis; in eight of 57 patients who had neither of these conditions, and in nine of 191 normal men and women. Observations are made on the antigens involved in these reactions and on the need for standardization of both reagents and techniques. PMID- 4214842 TI - Alteration of classically conditioned heart rate by operant reinforcement in monkeys. PMID- 4214841 TI - Tests of disinfection by heat in a bedpan washing machine. AB - Tests of effectiveness of disinfection of metal and polypropylene bedpans were made in a washer fitted with a steam generator. Broth cultures of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, or Streptococcus faecalis (approximately 4 x 10(8) organisms) were sealed in lengths of capillary tubing and attached to the surface of the pans. In other tests, pans were contaminated with an artificial soil containing Str. faecalis (10(8) organisms/ml). In both series of tests, counts of surviving organisms were made at the end of the washing and disinfection cycle. The tests using capillary tubes showed that the Gram-negative bacilli were effectively killed, but not necessarily Gram-positive cocci. However, when incorporated in standard soil, Str. faecalis was killed or removed during the cycle. The results indicate that the disinfection process was effective for metal bedpans, but less so for polypropylene. Possible disadvantages and modification of the machine are suggested. PMID- 4214843 TI - Effects of sequential preoptic and mammillary lesions on male rat sexual behavior. PMID- 4214844 TI - Behavioral diversity in ten species of nonhuman primates. PMID- 4214845 TI - Acid etching: questions and answers. PMID- 4214846 TI - The health care revolution (or dental practice will never be the same). PMID- 4214847 TI - Mouth guards in contact sports. PMID- 4214848 TI - (Need) divided by x minus (Demand) divided by xR equals orthodontist glut. PMID- 4214849 TI - Correction of trauma from occlusion in treatment of periodontal disease. PMID- 4214850 TI - "Sorry doctor, but I disagree". PMID- 4214851 TI - Ability to function with full dentures, natural dentition, and no dentition. PMID- 4214852 TI - Factors affecting L-alanine induced germination of Bacillus spores. PMID- 4214853 TI - Total viable count of microorganisms in the infected dental pulp. PMID- 4214854 TI - Fate of polychlorinated biphenyls, metals, and other elements in papers fed to lactating cows. PMID- 4214855 TI - [A comparison of the pathogenicity of two strains of Schistosoma mansoni in Cercopithecus aethiops monkeys in the Sudan]. PMID- 4214856 TI - A cytochemical approach to the lipid composition of mitochondrial matrix granules in brown adipose tissue and liver. PMID- 4214857 TI - First cases of diphtheria in Aruba (Dutch West Indies). PMID- 4214858 TI - Contribution to knowledge of factors participating in virulence of Listeria monocytogenes. II. Study of the chemical nature of complex Ei. PMID- 4214859 TI - Isolation of type - specific substances from Corynebacterium diphthermiae cells. PMID- 4214860 TI - Shigella surveillance in Czechoslovakia. PMID- 4214861 TI - The phases of Coxiella burneti and its immunosorbents. PMID- 4214862 TI - Allergens of mammalian origin. III. Properties of a major feline allergen. PMID- 4214863 TI - Antibodies to proteins dissolved in sodium dodecyl sulfate. PMID- 4214864 TI - Cross-idiotypic specificity of rat antibodies to group A streptococcal carbohydrate. PMID- 4214865 TI - Anti-idiotypic antibody in rat transplantation immunity. I. Production of anti idiotypic antibody in animals repeatedly immunized with alloantigens. PMID- 4214866 TI - Mononuclear cell chemotactic activity of kallikrein and plasminogen activator and its inhibition by C1 inhibitor and alpha 2-macroglobulin. PMID- 4214867 TI - Expression of IgG allotypes in human lymphoid tumor lines serially transplantable in the neonatal Syrian hamster. PMID- 4214868 TI - Molecular analysis of the reaction of C9 with EAC1-8: reaction of C9 with EAC1-8. PMID- 4214869 TI - Cellular immunity to Leishmania donovani. I. The effect of T cell depletion on resistance to L. donovani in mice. PMID- 4214870 TI - A pathologic IgM occurring in serum as pentamer, dimer, and monomer. PMID- 4214871 TI - Photography of faint immunodiffusion zones. PMID- 4214872 TI - A controlled quantitative study of parotid salivary secretory IgA-globulin in normal adults. PMID- 4214873 TI - Study of adenovirus hexon antigen--antibody reactions by single radial diffusion techniques. PMID- 4214874 TI - The use of peroxidase-labelled antiglobulin for ultrastructural localization of tissue antigens reacting with serum antibodies. PMID- 4214875 TI - Radioimmunoassay techniques for detecting naturally occurring viral antibody in human sera. PMID- 4214876 TI - Staphylococcal toxic epidermal necrolysis (TEN): the expanded mouse model. PMID- 4214877 TI - Chromatographic fractionation and partial characterization of acid phosphatase in guinea-pig epidermis. PMID- 4214878 TI - Histidase activity in rat liver and epidermis. PMID- 4214879 TI - Serum immunoglobulin in scabies. PMID- 4214880 TI - In vitro studies of the action of antibiotics on Rickettsia prowazeki by two basic methods of cell culture. PMID- 4214881 TI - Chute-hydropulping waste disposal system: a reservoir of enteric bacilli and pseudomonas in a modern hospital. PMID- 4214882 TI - The case for gonococcal serology. PMID- 4214883 TI - [Clinical and experimental studies of chronic respiratory infection caused by Haemophilus influenzae]. PMID- 4214884 TI - [Hematological and urine tests in epidemic hemorrhageic fever]. PMID- 4214885 TI - [Results of cephalexin (Larixin) treatment in various infections]. PMID- 4214886 TI - [Amino acid sequences of the tryptic peptides from the beta chain of hemoglobin of tufted capuchin monkey (Cebus apella) (author's transl)]. PMID- 4214887 TI - Pharyngo-cutaneous fistulae in totally laryngectomized patients. PMID- 4214888 TI - Why accelerators in radiation therapy? PMID- 4214889 TI - Breast cancer management. PMID- 4214890 TI - The involvement of lactoferrin in the hyposideremia of acute inflammation. AB - The hyposideremia of inflammation was found to be based on a three-step mechanism involving lactoferrin, the iron-binding protein from the specific granules of neutrophilic leukocytes. (a) Lactoferrin is Released from Neutrophils in an Iron Free Form. When phagocytosis was induced in neutrophils by zymosan or bacteria, lactoferrin was recovered in the incubation medium together with other constituents of the specific granules, such as alkaline phosphatase and lysozyme. Lactoferrin extracted from leukocytes was able to bind the amount of iron corresponding to its theoretical iron-binding capacity. After injection of endotoxin into rats, lactoferrin was detected in various tissues where it was normally absent, or in the plasma when the reticuloendothelial system (RES) had previously been blocked by injections of India ink or aggregated albumin. (b) Lactoferrin is Able to Remove the Iron from Transferrin. Significant exchange of iron from transferrin to lactoferrin was observed in vitro only at a pH below 7.0 or in the presence of a high concentration of citrate. However, the fast elimination of lactoferrin in vivo, when saturated with iron, might account for the observed transfer of iron to endogenous or administered apolactoferrin. Intravenous injection of human apolactoferrin into rats caused a marked decrease of the plasma iron level. The kinetics of this process, as well as controls with other proteins, ruled out the possibility of a secondary inflammatory effect due to phlogogenic contaminants. (c) Fe-Lactoferrin is Taken-up by the RES. By immunofluorescence, lactoferrin was shown to be bound and ingested by monocytes. The rate of elimination of human Fe-lactoferrin injected into rats was particularly fast when compared to that of human apolactoferrin, succinylated Fe lactoferrin, or other human proteins. Blockade of the RES slowed down the rate of clearance of Fe-lactoferrin and was also found to retard the elimination of endogenous rat lactoferrin released by endotoxin. These experiments suggest the existence of specific receptors for Fe-lactoferrin on the membrane of macrophages. PMID- 4214891 TI - The interaction of IgE with rat basophilic leukemia cells. II. Quantitative aspects of the binding reaction. AB - Previous studies indicated that cultured rat basophilic leukemia cells have surface receptors which bind IgE with high specificity. In this paper we describe some quantitative aspects of the phenomenon. The reaction mechanism appears to consist of a simple reversible binding reaction with k(1) = 9.6 x 10(4) M(-1) sec(-1) and k(-1) 1.6 x 10(-5) sec(-1) at 37 degrees C. The calculated K(A) is therefore 6 x 10(9) M(-1). The activation energy of binding was found to be 7.8 kcal/mol. The number of binding sites/cell varied between 3 x 10(5) to over 1 x 10(6). The binding was insensitive to pH's between 6-8 but at pH 3.0 complete dissociation of bound IgE occurred in approximately 1 min at 0 degrees C leaving the receptors for IgE intact. Ca(++) plus EDTA and Mg(++) plus EDTA produce a fairly marked reduction in binding capacity though these reagents alone produce much smaller effects. PMID- 4214892 TI - Further observations on genetic transformation in pseudomonas. PMID- 4214893 TI - The effect of proflavin, ethidium bromide and an elevated temperature on the appearance of nisin-negative clones in nisin-producing strains of Streptococcus lactis. PMID- 4214894 TI - Properties of a mutant of Pseudomonas aeruginosa affected in aerobic growth. PMID- 4214895 TI - Control of macromolecular composition and cell division in the blue-green algae Anacystis nidulans. PMID- 4214896 TI - Selection of a mutant of Bacillus subtilis deficient in glucose-6-phosphate dehydrogenase and phosphoglucoisomerase. PMID- 4214897 TI - Comparison of antigenic glycoproteins and glycoprotein receptors of concanavalin A isolated from duck embryo cells infected with Marek's disease virus and a herpes virus of turkeys (strain FC126). PMID- 4214898 TI - Alterations of the immunological specificity of plasma membranes from cells infected with Marek's disease and turkey herpes viruses. PMID- 4214899 TI - Photosensitization of cyanophage N-1. PMID- 4214900 TI - Studies to improve fixation of human nerves. 1. Effect of duration of glutaraldehyde fixation on peripheral nerve morphometry. PMID- 4214901 TI - Studies to improve fixation of human nerves. 2. Effect of time elapsed between death and glutaraldehyde fixation on relationship of axonal area to number of myelin lamellae. PMID- 4214902 TI - An economic, semiautomatic method for in vitro thyroid function tests. PMID- 4214903 TI - Responses of growing lambs to abomasal infusion of corn oil, starch, casein, and amino acid mixtures. PMID- 4214904 TI - Response of nitrogen metabolism, plasma amino acids and insulin levels to various levels of methionine infusion in sheep. PMID- 4214905 TI - Biological tests of a temporary crown and bridge material. PMID- 4214906 TI - Isolation and partial characterization of exo- and endoantigens of Cooperia punctata cultured in vitro. PMID- 4214907 TI - Studies on host-parasite relationships of Simuliidae with mermithids and microsporidans. PMID- 4214908 TI - Entopolypoides macaci (Babesiidae) in Macaca mulatta. PMID- 4214909 TI - Immunochemical studies on East Coast fever. I. Partial segregation and characterization of the Theileria parva schizont antigen. PMID- 4214910 TI - Immunochemical studies on East Coast fever. II. Partial segregation and characterization of the Theileria parva piroplasm antigen. PMID- 4214911 TI - Immunochemical studies on East Coast fever. III. Development of an indirect hemagglutination assay using Theileria parva piroplasm antigen. PMID- 4214912 TI - Pulmonary parenchymal damage complicating intravenous alimentation. PMID- 4214913 TI - Variations in intravenous nutrition in the management of catabolic states in infants and children. PMID- 4214914 TI - Syntheses and antimicrobial properties of isothiocyanate derivatives. PMID- 4214915 TI - Transport mechanisms of beta-lactam antibiotics across everted rat gut. PMID- 4214916 TI - Letter: Development of a stable sublingual nitroglycerin tablet I: interaction of nitroglycerin with selected macromolecules. PMID- 4214917 TI - Photoelectron spectra, hydrolytic stability, and antimicrobial activity of N chlorinated piperidines. PMID- 4214918 TI - Formulation and in vitro evaluation of anti-infective dry foams. PMID- 4214919 TI - Synthesis and antibacterial activity of 5-nitro-2-furfurylidene p-sulfonyl- and p sulfamoylbenzoylhydrazides. VII. PMID- 4214920 TI - Isolation of an acidic glycoprotein from rabbit oviducal fluid and its association with the egg coating. PMID- 4214921 TI - Calcium and zinc in the endometrium and uterine flushings of the roe deer (Capreolus capreolus) during delayed implantation. PMID- 4214922 TI - Failure to demonstrate a role for the acute release of prolactin at oestrus in the ewe. PMID- 4214923 TI - A technique for obtaining precise chromosome and bilirubin studies on amniotic fluid in twin pregnancy. PMID- 4214924 TI - Synthesis and antifolate activity of isoaminopterin. PMID- 4214925 TI - Pyrimido(4,5-c)isoquinolines. 2. Synthesis and biological evaluation of some 6 alkyl-,6-aralkyl-, and 6-aryl-1,3-diamino-7,8,9,10-tetrahydropyrimido(4,5 c)isoquinolines as potential folate antagnoists 1. PMID- 4214926 TI - Effect of lipophilic substituents on some biological properties of indoles. PMID- 4214927 TI - Selective binding of metal ions to macromolecules using bifunctional analogs of EDTA. PMID- 4214928 TI - Methotrexate analogs. 4.7-Methyl derivatives of methotrexate and dichloromethotrexate. A new synthesis and some biological studies. PMID- 4214929 TI - Semisynthetic beta-lactam antibiotics. 6. 1 Sulfocephalosporins and their antipseudomonal activities. PMID- 4214930 TI - Familial thyroxine-binding globulin deficiency: search for linkage with Xg blood groups. PMID- 4214931 TI - Electrical properties and diffusion potentials in the gallbladder of man, monkey, dog, goose and rabbit. PMID- 4214932 TI - A comparison of three different electron microscopical grade glutaraldehydes used to fix ovarian tissue. PMID- 4214933 TI - Sporulation-specific translational discrimination in Bacillus subtilis. PMID- 4214934 TI - Isolation by affinity chromatography of a precursor head protein (P23) of bacteriophage T4. PMID- 4214935 TI - Purification and properties of the isolated honeybee Z-disc. PMID- 4214936 TI - Effects of aminoethylation of cysteine residues on the structural and functional activities of the Escherichia coli 30 S ribosomal proteins. PMID- 4214937 TI - Characterization of an antiserum against human myeloma cells. PMID- 4214938 TI - Isolation of papovavirus from brain tumor and urine of a patient with Wiskott Aldrich syndrome. PMID- 4214939 TI - An in vitro micromethod for testing cytotoxic compounds. PMID- 4214940 TI - On diploid cell lines. PMID- 4214941 TI - Research on tissue culture at the National Cancer Institute, with special reference to the contributions of Dr. Virginia J. Evans. PMID- 4214942 TI - Alveolar macrophage in the burned rat. PMID- 4214943 TI - Treatment of open crushing type of industrial injuries of the hand and forearm: degloving, open circumferential, heat-press, and nail-bed injuries. PMID- 4214944 TI - Bacteriophage PBS2-induced deoxycytidine triphosphate deaminase in Bacillus subtilis. AB - The dCTP deaminase induced by Bacillus subtilis bacteriophage PBS2, whose DNA contains uracil instead of thymine, requires metal ion and thiol activators and has a molecular weight of 125,000. The enzyme displays sigmoidal substrate saturation kinetics and inhibition by dUTP, consistent with the deaminase's proposed role of providing balanced levels of dUTP and dCTP for PBS2 uracil-DNA synthesis. PMID- 4214945 TI - Bacillus subtilis DNA polymerase III is required for the replication of the virulent bacteriophage phi e. AB - The virulent phage phie of Bacillus subtilis which contains hydroxymethyluracil in its DNA requires host DNA polymerase III for its DNA replication. DNA polymerase III(ts) mutant cells infected with phie at restrictive temperatures do not support phage DNA synthesis. However, phie grows normally both at low and high temperatures in the mutant's parent strain and in spontaneous DNA polymerase III(+) revertants isolated from the mutant strain. Temperature-shift-down experiments with phie-infected cells having thermosensitive DNA polymerase III (pol III(ts)) indicate that at 48 C the thermolabile DNA polymerase III is irreversibly inactivated and has to be synthesized de novo after the shift to 37 C, before phage DNA synthesis can begin. Temperature-shift-up experiments with phie-infected mutant cells show that phage replication is arrested immediately after the temperature shift and indicate that phie requires DNA polymerase III throughout its replication stage. PMID- 4214946 TI - Transduction in Bacillus subtilis by bacteriophage SPP1. AB - Lysates of the virulent bacteriophage SPP1 were shown to be capable of mediating generalized transduction. Suppressible mutants of this bacteriophage (sus) were capable of transduction at a lower multiplicity of infection than virulent SPP1. Linkage analysis demonstrated that bacteriophage SPP1 transduced segments of the genome equal in size to that transferred by SP10. This bacteriophage should be useful in analyzing the regions of the genome where PBS1 appears to give anomalous results. PMID- 4214947 TI - Mixed infections of Bacillus subtilis involving bacteriophages SP82 and beta 22. AB - Progeny yields and the synthesis of nucleic acids have been investigated in two strains of Bacillus subtilis mixedly infected with two unrelated phages, SP82 and beta22. When B. subtilis strain 168 was the host, the first phage added dominated the infection; when B. subtilis strain SB11 was the host, beta22 produced progeny even when added to cells 5 min after infection with SP82. Dominance in these mixed infections could be correlated with qualitative and quantitative differences in the synthesis of phage-specific RNAs. PMID- 4214948 TI - Induction of prophage SPO2 in Bacillus subtilis by 6-(para) hydroxyphenylazouracil. AB - DNA replication in Bacillus subtilis is reversibly inhibited by 6-(para) hydroxyphenylazouracil (HpUra) (1971), whereas replication of temperature phage SPO2 is not affected by the drug. Experiments are presented which show that HpUra will induce bacteria lysogenic for SPO2. Also, prophage phi105, which is sensitive to the drug, is induced by HpUra. Induction of SPO2 lysogenics in the presence of HpUra gives selective synthesis of SPO2 DNA. PMID- 4214949 TI - Induction of prophage SPO2 in Bacillus subtilis: prophage excision in the absence of bacterial or bacteriophage DNA synthesis. AB - Bacillus subtilis lysogenic for SPO2 wild type was induced under conditions preventing synthesis of both bacterial and phage DNA. The infectivity of phage DNA in transfection is strongly decreased under these conditions, whereas the activity of single phage genes as measured by marker rescue with superinfecting phage is unaffected. DNA from induced cells was sedimented in neutral sucrose gradients. After induction, phage DNA was detected at a position in the gradients, which was different from the bulk of the bacterial DNA, corresponding to linear double-stranded DNA of about 25 x 10(6) daltons. Similar results were obtained with bacteria lysogenic for a SPO2 prophage carrying a DNA-negative mutation. No separation of phage and bacterial DNA activity was detected when chloramphenicol was present during the induction period. These experiments show that prophage SPO2 can excise from the bacterial chromosome without previous replication. PMID- 4214951 TI - In vivo and in vitro transcription of SPP1 DNA by host RNA polymerase. AB - Most (if not all) SPP1 RNA can be synthesized in infected cells in the presence of chloramphenicol, or in vitro by Bacillus subtilis RNA polymerase. PMID- 4214950 TI - Origin and metabolic properties of the RNA species formed during the replication cycle of virus 2C. AB - When short pulses of [(3)H]uracil were administered to Bacillus subtilis infected with phage 2C, the main species of labeled RNA was a 10S component that hybridized chiefly, but not exclusively, with the heavy strand of 2C DNA. After long pulses, most of the radioactivity was found in the 23S, 16S, and 5S rRNA's, which are coded for by the cell genome. Formation of such RNA species was reduced but not suppressed upon infection, the extent of inhibition being proportional to the virus-to-cell ratio. When bacteria were incubated with virginiamycin, an inhibitor of protein synthesis, and then infected with phage 2C, formation of virus-specific RNA decreased. This antibiotic also reduced the preferential transcription of the heavy strand of 2C DNA. The methylation pattern of rRNA remained unchanged upon infection with phage 2C. Virginiamycin reduced both the methylation and stability of rRNA in uninfected cells; this effect, however, was clearly reduced during the viral cycle. It can be concluded that in 2C-infected B. subtilis, cellular and viral RNA species are simultaneously synthesized and a preferential transcription of viral message depends not only on the number of available copies of viral template, but also on their translation. Moreover, virus-dictated proteins are responsible for the inhibition of cellular RNA formation as well as for the asymmetrical transcription of phage genome. Finally, virginiamycin and phage 2C have antagonistic, nonoverlapping effects on the metabolism and function of the RNA of the host cell. PMID- 4214952 TI - [Symposium: Immunity enhancing adjuvants--active substances and the mechanism of action. (1) Freund's adjuvant]. PMID- 4214953 TI - [Diverticulosis of the digestive system]. PMID- 4214954 TI - A statistical method for comparison and classification of the microfilarial periodicity. PMID- 4214955 TI - Pathogenic and antigenic properties of the Tyzzer's organisms from feline and hamster cases. PMID- 4214956 TI - A comparative study of mycobacteria from patients' room dusts and from sputa of tuberculous patients. Source of pathogenic mycobacteria occurring in the sputa of tuberculous patients as casual isolates. PMID- 4214957 TI - Preparation of an adjuvant-active, tuberculin-free peptidoglycolipid from human tubercle bacilli. PMID- 4214958 TI - Further confirmation of the avirulence of Streptococcus faecalis strain BIO-4R. PMID- 4214960 TI - [Successuflly treated chylopericardium with MCT after removal of pericardial diverticulum]. PMID- 4214959 TI - Littre's femoral hernia causing intestinal fistula. PMID- 4214961 TI - [Bacteriological relapse among the previously treated advanced pulmonary tuberculosis patients whose sputum converted to negative by the rifampicin treatment, with special reference to the duration of rifampicin administration (author's transl)]. PMID- 4214962 TI - [Significance of cord factor in pathogenesis of tuberculosis (author's transl)]. PMID- 4214963 TI - [Comparative evaluation of certain modifications of the passive hemagglutination reaction in detection of antituberculosis antibodies]. PMID- 4214964 TI - [Rapid processing of material for the antibody neutralization test in case of detection of antigen of tularemia and F-1 plague]. PMID- 4214965 TI - Further scanning electron microscope studies of the human glomerulus. PMID- 4214966 TI - The ultrastructure of the skin in patients with mucopolysaccharidoses. PMID- 4214967 TI - The content of some B-group vitamins in single-variety apple juices and commercial ciders. PMID- 4214968 TI - Progesterone and oestrogen metabolism in the pregnant marmoset (Callithrix jacchus). PMID- 4214969 TI - Detection of hepatitis-associated antigen. The latex agglutination test. PMID- 4214970 TI - Esophageal physiology. PMID- 4214971 TI - Gastrointestinal alterations in protein-calorie malnutrition. PMID- 4214972 TI - [The Tynnered project--viewpoints on long time drug usage in outpatient care]. PMID- 4214973 TI - [Sarcomatous transformation of lymphoreticulocytic hyperplasia in morbus Waldenstrom (author's transl)]. PMID- 4214974 TI - [New medical devices from polymeric materials]. PMID- 4214975 TI - [Control of oral anticoagulant therapy using the Hepato-Quick-test]. PMID- 4214976 TI - [A case of Leri-Joanny melorheostosis]. PMID- 4214977 TI - Amino acid metabolism in parenteral nutrition: with special reference to the calorie: nitrogen ratio and the blood urea nitrogen level. PMID- 4214978 TI - Medicine and millions. PMID- 4214979 TI - Letter: Psychosis associated with sympathomimetic and cromoglycate therapy. PMID- 4214980 TI - Editorial: Famine in Ethiopia. PMID- 4214981 TI - Total parenteral nutrition in paediatric patients. PMID- 4214982 TI - Editorial: Management of maternal isoimmunization. PMID- 4214983 TI - The liquor amnii bilirubin-protein ratio in the management of Rhesus isoimmunization. PMID- 4214984 TI - Tobramycin therapy in renal failure. PMID- 4214985 TI - [Non-specific basic therapy of leukemias and their complications]. PMID- 4214986 TI - [Acute complications of transfusion--from the viewpoint of the clinical practitioner]. PMID- 4214988 TI - Experimental determination of the need for multitaper collimators for neutron radiotherapy. PMID- 4214987 TI - Bremsstrahlung radiators and beam filters for 25-MeV cancer therapy. PMID- 4214989 TI - [A case of anterior urethral valves associated with other complex malformations of the urinary tract]. PMID- 4214990 TI - The specificity of transcription in vitro of the tryptophan operon of Escherichia coli. II. The effect of Rho factor. PMID- 4214991 TI - Biosynthesis of RNA polymerase in Escherichia coli. I. Control of RNA polymerase content at various growth rates. PMID- 4214992 TI - The analog inhibitor, alpha-methyl dopa, as a screening agent for mutants elevating levels of dopa decarboxylase activity in Drosophila melanogaster. PMID- 4214993 TI - Transformation in Bacillus subtilis using excreted DNA. PMID- 4214994 TI - A spectrophotometric study of the interaction of deoxyribonucleoproteins with the acriflavine-phosphotungstic acid complex. PMID- 4214995 TI - Macromolecular structure of the DNA of Bacillus bacteriophages. PMID- 4214996 TI - Errors in DNA replication in bacteria in the presence of a thymidylic acid deficiency. PMID- 4214997 TI - The Bacillus megaterium ribonucleotide reductase: evidence for a B 12 coenzyme requirement. PMID- 4214998 TI - Separation of two monoamine oxidases from bovine bran. PMID- 4214999 TI - Production of L-phenylalanine by DL-phenylalanine hydroxamate-resistant Tyr- mutants of Bacillus subtilis. PMID- 4215000 TI - Isolation and characterization of a 5S RNA-protein complex from human placental ribosomes. PMID- 4215001 TI - [Serological problems in the diagnosis of protozoal diseases (author's transl)]. PMID- 4215002 TI - [Immunological diagnosis of human helminthiasis (author's transl)]. PMID- 4215004 TI - [Studies on the degree of toxoplasmosis contamination in the population of Berlin West (author's transl)]. PMID- 4215003 TI - [Toxoplasma infections in domestic animals and their importance for toxoplasmosis in humans (author's transl)]. PMID- 4215005 TI - [Helminthiasis in the Heidelberg region (author's transl)]. PMID- 4215006 TI - ["Cercarial dermatitis" (author's transl)]. PMID- 4215007 TI - [Diagnostic bilance (medical audit) of a medical hospital department]. PMID- 4215008 TI - [Gluacoma problems yesterday, today, tomorrow]. PMID- 4215009 TI - [Clinically significant extraocular influences on intraocular pressure]. PMID- 4215010 TI - [Intra-ocular pressure and blood pressure in glaucoma (author's transl)]. PMID- 4215011 TI - [Glaucoma and hypertension (author's transl)]. PMID- 4215012 TI - [Glaucomatous atrophy of the optic disk. Advances in the determination of arterial pressure in the orbit (author's transl)]. PMID- 4215013 TI - [New procedures for the operative treatment of congenital glaucoma. A comparative investigation (author's transl)]. PMID- 4215014 TI - [Longterm observation after treatment of osteoporosis with sodium fluoride (author's transl)]. PMID- 4215015 TI - [The resistance of staphylococcus aureus to fucidine since 1970 compared to other effective antibacterial substances (author's transl)]. PMID- 4215016 TI - Investigation on radiosensitive and radioresistant populations of Drosophila melanogaster. VI. Selection for further increase in relative radioresistance of stage-7 oocytes of the irradiated population RO I. PMID- 4215017 TI - Dose protraction and induced compound autosome non-disjunction in immature oocytes of Drosophila melanogaster. PMID- 4215018 TI - The effects of radiation exposure-rate and exposure fractionation on the frequencies of recessive and dominant lethals in immature oocytes of Drosophila melanogaster. PMID- 4215019 TI - A model to explain the response of stage 7 oocytes of Drosophila to the induction of dominant lethals under conditions of exposure-protraction and fractionation. PMID- 4215020 TI - The development and evaluation of immunodiffusion, immunofluorescence and physiological tests for the differentiation of atypical Trichophyton rubrum and T. mentagrophytes isolates. PMID- 4215021 TI - Failure of disodium etidronate in calcinosis due to dermatomyositis and scleroderma. PMID- 4215022 TI - Letter: TRH and urinary urgency. PMID- 4215023 TI - Letter: Children, diabetic ketoacidosis, 2-3-DPG, and growth potentials. PMID- 4215024 TI - Medicine and Public Affairs. From the tapes: Mr. Nixon on cholesterol, insomnia, etc. PMID- 4215025 TI - Release of enzymes from cell walls by an endopectate-trans-eliminase. PMID- 4215026 TI - New RNA polymerase from Bacillus subtilis infected with phage PBS2. PMID- 4215027 TI - In vitro activity of cells from genetically lethal embryos of Drosophila. PMID- 4215028 TI - Sensitivity of cytotoxic T cells to T-cell mediated cytotoxicity. PMID- 4215029 TI - TRH: a possible mediator of thermoregulation. PMID- 4215030 TI - Transfection of non-host bacterial spheroplasts with bacteriophage phi chi 174 DNA. PMID- 4215031 TI - Decline of PCB concentrations in North Atlantic surface water. PMID- 4215032 TI - Precocious development of detoxicating enzymes following pituitary graft. PMID- 4215033 TI - Presence of J chain in human immunocytes containing various immunoglobulin classes. PMID- 4215034 TI - Bacterial mutation affecting T4 phage DNA synthesis and tail production. PMID- 4215035 TI - Evidence for a direct effect of LRF and TRF on single unit activity in the rostral hypothalamus. PMID- 4215036 TI - Editorial: Intercellular junctions: sites of permeability barriers and cellular communication. PMID- 4215037 TI - Neutrophil function in congenital phosphoglycerate kinase deficiency. PMID- 4215038 TI - In vitro maturation of precursors of 5S ribosomal RNA from Bacillus subtilis. PMID- 4215039 TI - Candidate for immunoglobulin D present on murine B lymphocytes. PMID- 4215040 TI - Immunoglobulin of T lymphoma cells is an integral membrane protein. PMID- 4215041 TI - Immunochemical analysis of IgD-lambda paraprotein in myeloma. PMID- 4215042 TI - [Morphologic and topographic aspects of the upper molars]. PMID- 4215043 TI - [A case of valium withdrawal with grand mal attacks. A case report on valium abuse and valium addiction]. PMID- 4215044 TI - Orosomucoid and haptoglobin excretion in rat glomerulonephritis and tubulonephritis. PMID- 4215045 TI - [Correlation between protein changes in the cerebrospinal fluid and the level of measles antibodies in patients with multiple sclerosis]. PMID- 4215046 TI - [Serum immunoglobulin level in patients with Wilson's disease]. PMID- 4215047 TI - [Treatment with a brain tissue hydrolysate. Clinical observations and results of experimental studies]. PMID- 4215048 TI - [Etiology of the chronic subdural hematoma (author's transl)]. PMID- 4215049 TI - [Double-blind clinical trial of a new coronary-active drug, MD 6753]. PMID- 4215051 TI - [Diagnostic problems in dental pathology and therapeutic]. PMID- 4215050 TI - [Human chorionic somatomammotropic hormone (placental lactogenic hormone). Biochemical, physiological and clinical aspects]. PMID- 4215052 TI - [Causes of extensive or entire crown destruction of the teeth of children (report of cases)]. PMID- 4215053 TI - [Diagnostic signs of occlusal trauma]. PMID- 4215054 TI - [Clinical definition of the frequency of cross-bite among Greek children 8-14 years old]. PMID- 4215055 TI - [Introduction to impression taking for the construction of complete dentures]. PMID- 4215056 TI - [Gingival curettage]. PMID- 4215057 TI - [One-year clinical observation of composite resins for class II restorations]. PMID- 4215058 TI - [Fractures of the maxillary tuberosity during extraction of posterior maxillary teeth and their management. 3 cases]. PMID- 4215059 TI - [Fracture of amalgam restorations]. PMID- 4215060 TI - [Waldenstrom macroglobulinemia, simulating muscular tumor. Data on radiosensitivity]. PMID- 4215061 TI - [Functional and pathomorphological comparisons in post-traumatic epilepsy]. PMID- 4215062 TI - Long-term management of heart defects. PMID- 4215063 TI - Diabetes mellitus in childhood. PMID- 4215064 TI - Breast-feeding: second thoughts. PMID- 4215065 TI - [Case of gargoylism in a 12-year-old girl]. PMID- 4215066 TI - Lupus nephritis: long-term follow-up. PMID- 4215067 TI - Rehabilitation of the long-stay schizophrenic. PMID- 4215068 TI - Nursing care study: a losing battle? PMID- 4215069 TI - Rheumatic diseases in the community. PMID- 4215070 TI - Boredom in long-stay hospitals. PMID- 4215071 TI - The SEN in the psychiatric hospital. PMID- 4215072 TI - [Value of determination of active thyroxine]. PMID- 4215073 TI - [Rapid method of serological selection of donor blood for isosensitized recipients]. PMID- 4215074 TI - Evidence for somatic generation of antibody diversity. AB - RNA preparations containing 70-80% mouse kappa-chain mRNA have been prepared. The remainder consists of many RNA species, each of which represents a small fraction of the total RNA. The kappa-chain mRNA preparation hybridizes with mouse liver DNA with bi-phasic kinetics, indicating that it consists of two fractions "unique" and "reiterated." Competition hybridization experiments show that the homology among the unique fractions from different mRNAs is the same as the homology among the amino acid sequences of the corresponding kappa-chains. Hence, in addition to the C-region (constant-region) sequences, (most of) the V-region (variable-region) sequences are also derived from unique germ line genes. The reiterated fractions from different kappa-chain mRNAs show essentially complete homology with each other. This fraction seems to consist mostly of sequences which do not code for amino-acid sequences of the secreted polypeptide chain, i.e., the "external" section of the mRNA molecule. It is concluded that the number of germ line genes is too small to account for the observed diversity of antibody molecules. PMID- 4215075 TI - Antiinflammatory effects of murine malignant cells. AB - Development of teratocarcinoma does not impair immunization of mice against Listeria monocytogenes. Endotoxin injection a short time before tumor cell inoculation allows the growth of teratocarcinoma in non syngenic mice despite immune stimulation. In contrast with this absence of impaired systematic immunity, teratocarcinoma cells were found to repulse macrophages in vitro. This effect on macrophages was also found with three other malignant cells and with trophoblast cells. In vivo, teratocarcinoma cells were found to impair local inflammation. These cells and other malignant cells are able to produce a compound(s) of molecular weight between 10(3) and 10(4), which prevents inflammatory reaction. These results suggest that mouse teratocarcinomas and other tumors by-pass the host immunological system of surveillance by at least two mechanisms: a direct toxic effect on macrophages and the release of an inhibitor of inflammation. The possible relations between these properties of malignant cells and physiological functions of trophoblast are discussed. PMID- 4215076 TI - Mouse immunoglobulin heavy chains are coded by multiple germ line variable region genes. AB - The N-terminal 20 residues of 13 heavy immunoglobulin chains from myeloma protein of the BALB/c mouse are compared with the same residues of 15 other heavy chains described in the literature. Sixteen of 28 sequences are different from one another. These proteins fall into four major sets, with 18 of the proteins in the largest set being further divisible into at least five subsets. This pattern of diversity suggests there are at least eight germ line genes coding for the variable regions of mouse heavy chain. Many of the immunoglobulins from which these heavy chains are derived exhibit binding activity for various haptens. The differing hapten specificities are closely correlated with distinct primary amino acid sequences. PMID- 4215077 TI - Deficiencies or excesses of metabolites interfering with differentiation. AB - Auxotrophic mutants of Bacillus subtilis need much higher concentrations of the required adenine, nicotinic acid, riboflavin, thiamine, or tryptophan for optimal sporulation than for maximal growth. Acetate can partially replace thiamine, indicating the importance of the pyruvate dehydrogenase system for differentiation. A glycerol-requiring mutant can sporulate only if its cells contain a small concentration of L-alpha-glycerol phosphate during development. This can best be achieved by excess (>/=5 mM) of extracellular alpha-glycerol phosphate, which enters B. subtilis very slowly. The results show that both biosynthetic and catabolic enzymes are often needed to maintain the precise balance of metabolites required for differentiation. Mutants unable to catabolize fructose 6-phosphate, glucose 6-phosphate, or alpha-glycerol phosphate do not sporulate as long as these compounds accumulate inside the cells; their development is blocked before prespore septa have formed. PMID- 4215078 TI - Highly purified colicin E3 contains immunity protein. AB - Colicin E3, even when highly purified, still contains about one molar equivalent of a second protein, "E3 immunity protein." The two proteins are bound together in a complex that can be dissociated only under strongly denaturing conditions, such as electrophoresis in sodium dodecyl sulfate-polyacrylamide gles or by gel filtration in 6 M guanidine.hydrochloride. Colicin and immunity protein were separated by preparative electrophoresis in sodium dodecyl sulfate-polyacrylamide gels. The immunity protein prepared in this way was shown to be functionally and immunologically identical to immunity protein purified from colicinogenic cells by other methods. Colicin E3 that had been freed of immunity protein was much more active than complexed colicin in inhibiting protein synthesis in vitro. PMID- 4215079 TI - Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. AB - Arachidonic acid incubated with human platelets was converted into three compounds, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, 12L-hydroxy-5,8,10 heptadecatrienoic acid, and the hemiacetal derivative of 8-(1-hydroxy-3 oxopropyl)-9,12L-dihydroxy-5,10-heptadecadienoic acid. The formation of the two latter compounds from arachidonic acid proceeded by pathways involving the enzyme, fatty acid cyclo-oxygenase, in the initial step and with the prostaglandin endoperoxide, PGG(2), as an intermediate. The first mentioned compound was formed from 12L-hydroperoxy-5,8,10,14-eicosatetraenoic acid, which in turn was formed from arachidonic acid by the action of a novel lipoxygenase. Aspirin and indomethacin inhibited the fatty acid cyclo-oxygenase but not the lipoxygenase, whereas 5,8,11,14-eicosatetraynoic acid inhibited both enzymes. The almost exclusive transformation of the endoperoxide structure into non prostaglandin derivatives supports the hypothesis that the endoperoxides can participate directly and not by way of the classical prostaglandins in regulation of cell functions. The observed transformations of arachidonic acid in platelets also explain the aggregating effect of this acid. PMID- 4215080 TI - The three-dimensional structure of the fab' fragment of a human myeloma immunoglobulin at 2.0-angstrom resolution. AB - The structural analysis of the Fab' fragment of human myeloma immunoglobulin IgGl(lambda) New has been extended to a nominal resolution of 2.0 A. Each of the structural subunits corresponding to the variable and to the constant homology regions of the light and heavy chains contains two irregular beta-sheets which are roughly parallel to each other and surround a tightly packed interior of hydrophobic side chains. About 50-60% of the amino-acid residues are included in beta-pleated sheets. Sequence alignments between the homology regions of Fab' New obtained by comparison of their three-dimensional structures are given. Some of the sequence variations observed in light and heavy chains and the role of the regions of hypervariable sequence in defining the size and shape of the active site of different immunoglobulin molecules are discussed on the basis of the three-dimensional model of Fab' New. PMID- 4215081 TI - The localization of transfer RNA5Lys genes in Drosophila melanogaster. AB - Transfer RNA(5) (Lys) was isolated and purified from Drosophila melanogaster. It was iodinated in vitro with sodium [(125)I]iodide and hybridized in situ to the polytene salivary gland chromosomes from Drosophila. Autoradiographs exposed three to four weeks allowed the localization of this tRNA to the right arm of chromosome 2 between bands 48F and 49A. PMID- 4215082 TI - Prostaglandin synthetase system--resolution into oxygenase and isomerase components. AB - The microsomal fraction of bovine vesicular gland catalyzed the conversion of [1 (14)C]8,11,14-eicosatrienoic acid to prostaglandin E(1) in the presence of tryptophan, hemoglobin, and glutathione. The prostaglandin synthetase system was solubilized by treatment of the microsomal fraction with Tween 20 in the presence of ethylene glycol. DEAE-cellulose column chromatography separated the enzyme into two fractions (Fractions I and II), both of which were required for prostaglandin E(1) synthesis. When Fraction I alone was incubated with 8,11,14 eicosatrienoic acid, an unstable compound accumulated. This compound was converted to prostaglandin E(1) by the addition of Fraction II. On the basis of its R(F) values on thin-layer chromatography, its reduction to prostaglandin F(1alpha) with stannous chloride, and the decomposition to prostaglandins F(1alpha), E(1), and D(1) at room temperature, the unstable intermediate was tentatively identified to be the 9,11-endoperoxide derivative, referred to previously as prostaglandin R(1) (Nugteren et al. (1973) Biochim. Biophys. Acta 326, 448-461) or prostaglandin H(1) (Hamberg et al. (1974) Proc. Nat. Acad. Sci. USA 71, 345-349). Of the three cofactors mentioned above, Fraction I required both tryptophan and hemoglobin, while only glutathione was necessary for Fraction II. Anti-inflammatory agents such as indomethacin and aspirin were inhibitory to Fraction I. PMID- 4215084 TI - Principles of fertilization. PMID- 4215083 TI - Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene. AB - Hybridization kinetic analyses with synthetic DNA indicate that there are only two to three copies of the kappa constant region gene per haploid genome. This result lends weight to the argument that the immunoglobulin light chain is encoded by more than one continuous gene sequence. PMID- 4215085 TI - Recent research on implantation in animals. PMID- 4215086 TI - Effects of some amino acids on the content and uptake of histamine by neoplastic mast cells in vitro. PMID- 4215087 TI - Enzyme derivatives containing reactive groups. Immobilization of alpha-amylase on human erythrocytes. PMID- 4215088 TI - Effect of sex and castration on hepatic and intestinal activity of drug metabolizing enzymes. PMID- 4215089 TI - Delayed pressor response to isoproterenol during alpha-adrenergic blockade. PMID- 4215090 TI - Proceedings: Behavioral effects of hypothalamic polypeptides in animals and man. PMID- 4215091 TI - Long-term methylphenidate treatment of hyperkinetic children. PMID- 4215092 TI - Long-term patients seen in an alcoholism clinic. PMID- 4215093 TI - Letter: Insensitivity of serially transferred Tetrahymena pyriformis W. to irradiated media. PMID- 4215095 TI - [Stability studies of Australia (SH) antigen in irradiation with a 60C0 therapy unit (author's transl)]. PMID- 4215096 TI - The roentgenographic manifestations of cutis laxa (generalized elastolysis). PMID- 4215097 TI - The radiographic findings in congenital cutis laxa. PMID- 4215098 TI - [Metabolism of fat soluble vitamins--retinol binding protein (author's transl)]. PMID- 4215099 TI - [The third component of complement and complement receptors (author's transl)]. PMID- 4215100 TI - The effects of prostaglandins, prostaglandin inhibitors, and oxygen on the closure of the ductus arteriosus, pulmonary arteries and umbilical vessels in vitro. PMID- 4215101 TI - [Usefulness of a selective medium in the diagnosis of gonorrhea]. PMID- 4215103 TI - [The status of Rh therapy 10 years after the initiation of the 1st studies]. PMID- 4215102 TI - Infections in cancer patients. I. Bacterial infections. PMID- 4215105 TI - [Comparative study of various parameters in the evaluation of the negative iso immunization Rh factor]. PMID- 4215106 TI - [Wilson's disease (experience of long-term treatment with penicillamine---con penicilamina]. PMID- 4215107 TI - [Factors affecting the digestibility, absorption and retention of calcium, oxalate, ethylen-diamine-tetracetic acid (disodium salt), nitril triacetic acid, lysine and protein quality (author's transl)]. PMID- 4215108 TI - [Alteration in water intake after the lesions of mammillary bodies (author's transl)]. PMID- 4215109 TI - Theileria parva: comparative infectivity of a ground tick stabilate and a classical 10-tick challenge. PMID- 4215110 TI - Comparative development and evolution of the placenta in primates. PMID- 4215111 TI - Evolutionary trends in primate sex cycles. PMID- 4215112 TI - Placental biosynthesis and metabolism of steroid hormones in primates. PMID- 4215113 TI - Comparative morphology of the primate ovary. PMID- 4215114 TI - Biology of primate spermatozoa. PMID- 4215115 TI - [Partial agenesis of the corpus callosum with multiple ocular abnormalities and exceptional chromosome aberration]. PMID- 4215116 TI - [Phonomechanographic systolic parameters of the left ventricle in the pre clinical form of chronic Chagas' diseases]. PMID- 4215117 TI - [Phonomechanocardiographic systolic parameters of the left ventricle and endocardial pacemaker--study in patients with chronic Chagas' disease]. PMID- 4215118 TI - Nursing challenges: treatment and care of the patient with hyperparathyroidism. PMID- 4215119 TI - [Megavolt treatment of radiation-resistant tumors with high single doses. Indications and clinical results]. PMID- 4215120 TI - [Esophageal diverticula]. PMID- 4215121 TI - Pathophysiology and current treatment of intestinal obstruction. PMID- 4215122 TI - A systematic study of variables affecting protein binding of thyroxine and triiodothyronine in serum. PMID- 4215123 TI - The hydrolysis of pteroylpolyglutamates in the small intestine. PMID- 4215124 TI - Influence of feeding and sham feeding upon serum gastrin and gastric acid secretion in control subjects and duodenal ulcer patients. PMID- 4215125 TI - Comparison of methods to diagnose deficiency or malabsorption of vitamin B12. PMID- 4215126 TI - Serum B12 determination using the radiosorbent technique and the Euglena gracilis assay. PMID- 4215127 TI - The absorption of vitamin B12 in the blind-loop syndrome. PMID- 4215128 TI - IgM turnover in chronic liver disease. PMID- 4215129 TI - [Immunological and electron microscopy demonstration of Australia antigen (Hepatitis B antigen) in feces and urine samples of patients with viral hepatitis B]. PMID- 4215130 TI - [Simultaneous oral anticoagulant and benzydamine therapy]. PMID- 4215131 TI - [Relations between plasma creatinine and glomerular filtrate determined by means of 2 different methods (Bonsnes-Taussky and Greiner analyzer II)]. PMID- 4215132 TI - [Total thyroxine and free thyroxine in endemic goiter in southern Baden]. PMID- 4215133 TI - [Sulfamethoxazole-trimethoprim: bacteriological experiences after 5 years of use]. PMID- 4215134 TI - Notions of morality in medical organization and practice. PMID- 4215135 TI - Mutagens and potential mutagens in the biosphere. I. DDT and its metabolites, polychlorinated biphenyls, chlorodioxins, polycyclic aromatic hydrocarbons, haloethers. PMID- 4215136 TI - Autoimmune haemolytic anaemia: serological and immunochemical characteristics of the autoantibodies; mechanisms of cell destruction. PMID- 4215137 TI - Autoimmune haemolytic disease in NZB mice. PMID- 4215138 TI - Studies of monkeys asphyxiated at birth: implications for minimal cerebral dysfunction. PMID- 4215139 TI - Proliferation and maturation of bone marrow-derived lymphocytes. PMID- 4215140 TI - The identification of mouse myeloma cells which have undergone mutations in immunoglobulin production. PMID- 4215141 TI - Cromolyn sodium therapy in childhood asthma. PMID- 4215142 TI - Current diagnosis and treatment of acute pancreatitis. PMID- 4215144 TI - The Indonesian developmental area study: observations on mammals from South and East Kalimantan (Borneo). PMID- 4215143 TI - Delayed recognition of lead encephalopathy in two "moonshine" drinkers. PMID- 4215146 TI - Sarcocystis from rats in Sulawesi, Indonesia. PMID- 4215145 TI - Pulmonary tuberculosis in a rural area of Sarawak, Malaysia. PMID- 4215147 TI - Observations on exflagellation of microgametocytes of Leucocytozoon sabrazesi. PMID- 4215148 TI - Leucocytozoon sabrazesi-first record from the Malayan jungle fowl, Gallus gallus spadiceus. PMID- 4215149 TI - Further stages of the "sporozoan" from the moon rat Echinosorex gymnurus, and its possible connection with Sarcocystis. PMID- 4215150 TI - The silvered leaf monkey as a natural host of the lung mite, Pneumonyssus simicola Banks, (Acarina: Halarachnidae) in Malaysia: a preliminary report. PMID- 4215151 TI - Cytological analysis of the variability of ring chromosomes in Drosophila. Communication II. Influence of temperature, the Gowen gene, and heterozygous inversion. PMID- 4215152 TI - A study of the homeotic genes antennopedix and nasobemia in Drosophila melanogaster. Communication II. Interaction of the homeotic antennopedix and nasobemia genes with the polycomb, multiple sex comb, aristapedia, and thread genes. PMID- 4215153 TI - Investigation of the genetics of the sexual behavior of Drosophila melanogaster. Communication III. Further genetic analysis of the lines differeing in sexual activity of the males. PMID- 4215155 TI - Development of mesosomes in Caryophanon. PMID- 4215154 TI - The mutagenic effect of nitrosoalkylamides on extracellular phages and bacterial transforming DNA. PMID- 4215156 TI - Letter: Intra-epithelial lymphocytes in the jejunum of malnourished children. PMID- 4215157 TI - Sterilisation of laryngoscope blades. A preliminary report. PMID- 4215158 TI - A comparison of oral feeding and total parenteral nutrition in infants of very low birthweight. PMID- 4215159 TI - Intravenous fructose disappearance in protein calorie malnutrition. PMID- 4215160 TI - Health care and justice. PMID- 4215161 TI - Fungi associated with common crops and crop products and their significance. PMID- 4215162 TI - Blood xylose concentrations in protein energy malnutrition. Relationship to serum albumin and jejunal histology. PMID- 4215163 TI - Hypercholesterolaemia and atherosclerosis induced in vervet monkeys by cholesterol-free, semisynthetic diets. PMID- 4215164 TI - Controversies in the management of potentially curable breast cancer. PMID- 4215165 TI - Topical burn wound therapy. PMID- 4215166 TI - Interdisciplinary approach to advanced ovarian cancer. PMID- 4215167 TI - Three varieties of congenital diverticulum of the intestine. PMID- 4215169 TI - [Diagnosis and complex treatment of dyskinesis of the biliary tract]. PMID- 4215168 TI - The relationship of genitourinary tract procedures and deep sepsis after total hip replacements. PMID- 4215170 TI - [Clinico-endoscopic parallels in diseases of the gastrointestinal tract]. PMID- 4215171 TI - Evaluating long-term periodontal therapy. PMID- 4215172 TI - Effect of physical activity before pregnancy on fetuses of mice exercised forcibly during pregnancy. PMID- 4215173 TI - Pseudomonas aeruginosa abscess masquerading as a slowly growing solitary pulmonary nodule. PMID- 4215174 TI - [The "in vitro" effect of gliclazide, a new hypoglycemic agent, on normal human blood platelets]. PMID- 4215175 TI - Maltose metabolism in diabetic state. PMID- 4215177 TI - Human hepatitis B antibody: evaluation of assays and development of a reference panel. PMID- 4215176 TI - A method for serial measurement of regional cortical metabolism and blood flow. PMID- 4215179 TI - Lesions of bladder muscle in baboons and monkeys infected with schistosoma haematobium. PMID- 4215178 TI - Immunological studies in patients receiving repeated allogeneic anc xenogeneic liver hemoperfusions. PMID- 4215180 TI - [Ciliate morphogenesis and its bearing on general cellular morphogenesis]. PMID- 4215181 TI - [Tuberculous meningitis in children. (70 cases)]. PMID- 4215182 TI - [2 cases of Wilson's disease diagnosed at the infra-clinical stage. Prolonged, early treatment using penicillamine. Result]. PMID- 4215183 TI - Symposium on renal lithiasis. Nutritional support of the azotemic patient. PMID- 4215184 TI - Hematuria in children. A guide in differential diagnosis. PMID- 4215186 TI - Intraprostatic injections of various antitumoral compounds into rats. PMID- 4215185 TI - Renal function after thyroidectomy and parathyroid hormone administration. An experimental study in the pig. PMID- 4215187 TI - Infection stones of prostate gland. Laboratory diagnosis and clinical management. PMID- 4215188 TI - Syndrome of dyspraxia and multifocal seizures associated with chronic hemodialysis. PMID- 4215189 TI - Long-term membrane oxygenation without systemic heparinization. PMID- 4215190 TI - Preliminary studies with the fistula catheter - a new vascular access prosthesis. PMID- 4215191 TI - Coated adsorbents for direct blood perfusion II. PMID- 4215192 TI - A new technique employing extracorporeal chemotherapy. PMID- 4215193 TI - Fundamental biophysical aspects of high-energy radiations in cancer therapy. PMID- 4215194 TI - [Effect of chronic focal infection of the maxillary sinuses on certain immunological indicators in children]. PMID- 4215196 TI - [Some current and perspective tasks of food hygiene in agriculture]. PMID- 4215195 TI - [Anaphylactoid reaction in a child after plasma transfusion]. PMID- 4215197 TI - [Catalase activity in various types of bovine and porcine adipose tissue]. PMID- 4215198 TI - [Effect of the oxidized fat component of feed mixtures on the stability of deposited and muscular fat in pigs]. PMID- 4215199 TI - [Effect of fat from rendering plants on the health condition, efficiency, vitamin E levels in organs and oxidative stability of the back fat of fattened pigs]. PMID- 4215200 TI - [Relations between enzymatic and nonenzymatic processes in the reduction of nitrate and nitrite in cured meat and meat products]. PMID- 4215201 TI - [Residua of antimicrobial substances in the meat and organs of emergency slaughtered and decreased calves]. PMID- 4215202 TI - [Effect of a disease on the quality of rabbit's meat]. PMID- 4215204 TI - [25 years of activity of the Veterinary School in Kosice]. PMID- 4215203 TI - [Hemolysins of Staphylococci isolated from milk and dairy products]. PMID- 4215205 TI - An unidentified sporozoan encephalomyelitis in sheep. PMID- 4215206 TI - Ultrastructural studies of spleens, brains, and brain cell cultures of mice with scrapie. PMID- 4215207 TI - Spontaneous malignant lymphoma in a new-world primate. PMID- 4215208 TI - Toxoplasma-like encephalomyelitis in the horse. PMID- 4215209 TI - Quantitative studies on serum immunoglobulin levels in suckled calves from birth to five weeks. PMID- 4215210 TI - Brucellosis in wildlife. PMID- 4215211 TI - Brucella abortus biotype 3 in Tanzania. PMID- 4215212 TI - In vitro interaction between phage and receptor lipopolysaccharide: a novel glycosidase associated with Salmonella phage epsilon15. PMID- 4215213 TI - Serological relationship between maize rough dwarf virus and rice black-streaked dwarf virus. PMID- 4215214 TI - Detection of mycoviruses using antiserum specific for dsRNA. PMID- 4215215 TI - Low-frequency specialized transduction with Bacillus subtilis bacteriophage phi 105. PMID- 4215216 TI - Bacteriophage gene expression in sporulating cells of Bacillus subtilis 168. PMID- 4215217 TI - Isolation and genetic mapping of temperature-sensitive mutants of cyanophage LPP2 SPI. PMID- 4215218 TI - Spectral sensitivity of the short wavelength mechanism in the squirrel monkey visual system. PMID- 4215219 TI - Inhibition of toad (Bufo bufo L) retinal on-off and off-ganglion cells via active eye closing. PMID- 4215220 TI - [In vitro effect of antitumor preparations on the hydrolase activity of lysosomes of tumor cells]. PMID- 4215222 TI - [Prognosis in cancer of the ovaries]. PMID- 4215221 TI - [Individual sensitivity of ovarian ascitic cancer to thiophosphamide]. PMID- 4215223 TI - [Drug therapy of cervical cancer]. PMID- 4215224 TI - [Clinical dosimetric studies of tissue heterogeneity in the pelvic area with irradiation on the Rokus and B5M-25 machines]. PMID- 4215225 TI - [First experience with stereotaxic surgery of the spinal cord for treatment of pain]. PMID- 4215226 TI - [Change in the concentration of immunoglobulins of the A, M and G classes in the blood serum in patients with rheumatism with a minimal degree of activity]. PMID- 4215227 TI - [Economic losses because of influenza and other respiratory infections and possibilities of their reduction]. PMID- 4215228 TI - [Character of microbial flora of the sputum in patients with chronic pneumonia]. PMID- 4215229 TI - [Immunoelectrophoresis and quantitative immunoelectrodiffusion of serum proteins in myeloma]. PMID- 4215230 TI - [Rare metabolic complications during the development of diabetes mellitus]. PMID- 4215231 TI - Old age--a problem for society as a whole. PMID- 4215232 TI - [A 14-year follow-up of a case of striated-cell myosarcoma in a patient with neurofibromatosis and numerous foci of basal cell skin carcinoma]. PMID- 4215233 TI - [The investigation of the endocrine partial functions in post-traumatic insufficiency of the anterior pituitary gland (author's transl)]. PMID- 4215234 TI - [Fatal lactic acidosis in a phenformin-treated diabetic (author's transl)]. PMID- 4215235 TI - [The treatment of irradiation cystitis (author's transl)]. PMID- 4215236 TI - [Immediate EEG changes produced by i.v. clonazepam medication--a new criterion for specific antiepileptic therapy (author's transl)]. PMID- 4215237 TI - [Heriditary patello-pelvic dysplasia (author's transl)]. PMID- 4215239 TI - Total parenteral alimentation. PMID- 4215238 TI - [Myoclonus: Features, pathophysiology and clinical importance]. PMID- 4215240 TI - Gonorrhea from birth through adolescence: local and systemic manifestations. PMID- 4215241 TI - [Heart rate as an expression of perceptive information processing]. PMID- 4215242 TI - The conjugation of indolylacetic acid in man, monkeys and other species. PMID- 4215243 TI - Rapid differentiation of certain bacteria in mixed populations by gas-liquid chromatography. PMID- 4215244 TI - [Recommendations for the management of parenteral feeding]. PMID- 4215245 TI - [Substitute stomach. Pathophysiology and surgical tactics]. PMID- 4215246 TI - [Immunoelectrophoretic findings in malignant reticuloses and reticulogranulomatoses]. PMID- 4215247 TI - [Comparison of two procedures to concentrate proteins of collected liquor cerebrospinalis. Studies on the protein electrophoresis of liquor cerebrospinalis with cellulose acetate membranes, I (author's transl)]. PMID- 4215249 TI - [Numbers, facts, data]. PMID- 4215248 TI - Studies on the methodical and biological variation of proteins quantitated by single radial immunodiffusion. PMID- 4215250 TI - [Cost explosion from the viewpoint of the nursing personnel]. PMID- 4215251 TI - [Proceedings: Effect of nitroglycerin in acute myocardial infarct]. PMID- 4215252 TI - [Proceedings: Coronary steal phenomenon in intracoronary infusion of adenosine, nitroglycerine, persantin, intensain and nifedipine]. PMID- 4215253 TI - [Proceedings: Influence of nitroglycerine and coronary vasodilatators on the regional myocardial circulation in coronary heart disease]. PMID- 4215254 TI - [Proceedings: Oral nitroglycerin preparations in the therapy of left heart failure in acute myocardial infarct]. PMID- 4215255 TI - [Proceedings: Hemodynamics before and after nitroglycerine in rest and during exertion in myocardial infarct patients: significance for the rehabilitation program]. PMID- 4215256 TI - Interaction of nutrition and infection: Trypanosoma lewisi, folic acid levels in sera and tissues of normal and folic acid-deficient rats. PMID- 4215257 TI - [Kanamycin in the treatment of patients with gonorrhea]. PMID- 4215258 TI - [Mathematical model of interaction of 2 populations. IV. Comparison of theory and experiment]. PMID- 4215260 TI - [Bovine calcinosis in Austria. II. Experimental induction of calcinosis in sheep and rabbits]. PMID- 4215259 TI - [Genuine cecal diverticulum in a child]. PMID- 4215261 TI - [Effect of hormonal agents on the gonads of semi-domestic pigeons]. PMID- 4215262 TI - [Adrenocortical function in farm animals. Cortisol and corticosterone determination using principles of concurrent protein binding analysis. 4: cattle]. PMID- 4215263 TI - The isoenzymes of lactate dehydrogenase of bovine thrombocytes. PMID- 4215264 TI - Developmental biochemistry of bovine foetal muscle. II. Collagen. PMID- 4215265 TI - [Perfusion cytophotometry, a simple and precise method for counting cells in milk]. PMID- 4215266 TI - Studies on the effect of temperature and glycerol on the inactivation of the virus of haemorrhagic septicaemia (VHS) of rainbow trout by use of the microtiter system. PMID- 4215267 TI - [Immunological aspects of the prevention of hemolytic disease of the newborn]. PMID- 4215268 TI - [Hypertension syndrome of non-tumor etiology in children]. PMID- 4215269 TI - Control of Pseudomonas aeruginosa infections. PMID- 4215271 TI - Immunoglobulins G, A, and M in bronchial asthma. PMID- 4215272 TI - Bronchial reactivity to inhaled histamine in asthmatic patients, before and after administration of atropine, phentolamine or disodium cromoglycate. PMID- 4215270 TI - Onset of diabetic ketoacidosis with symptoms of acute abdomen during oral mestranol treatment. PMID- 4215274 TI - Selection of patients for cromolyn therapy. PMID- 4215273 TI - New developments in asthma therapy. PMID- 4215275 TI - Environmental factors and host responses in asthma. PMID- 4215276 TI - Comparative nitrogen balance studies with an amino-acid solution based on nutritional studies against two protein-based solutions. PMID- 4215277 TI - Fine structural localization of alkaline phosphatase activity of the female genital canal surface during the estrous cycle and after castration in rats. PMID- 4215278 TI - Cystine: a semi-essential amino acid in the newborn infant. PMID- 4215279 TI - Resting metabolic rate in malnourished babies in relation to total body potassium. PMID- 4215280 TI - Pseudomonas aeruginosa infection in cystic fibrosis. Occurrence of precipitating antibodies against pseudomonas aeruginosa in relation to the concentration of sixteen serum proteins and the clinical and radiographical status of the lungs. PMID- 4215281 TI - The isolation of Mycoplasma primatum during an autopsy study of the mycoplasma flora of the human urinary tract. PMID- 4215282 TI - Mutations in Arthrobacter affecting formation of extracellular protease. PMID- 4215283 TI - Infection of Arvicola terrestris (vole rat) with M. tuberculosis and M. bovis. PMID- 4215284 TI - Antimycobacterial antibodies in sera from patients throughout the clinico pathological disease spectrum of leprosy. PMID- 4215285 TI - Determination of antistreptolysin O by reversed single radial immunodiffusion. PMID- 4215286 TI - [Determination of calcium, sodium, potassium and magnesium in human blood sera by atomic absorption]. PMID- 4215287 TI - DDT and related substances: effects on permeability properties of myelinated xenopus nerve fibre. Potential clamp analysis. PMID- 4215288 TI - [The development of schizophrenia seen as a territorial conflict]. PMID- 4215289 TI - (14C)adenine uptake into Bacillus anthracis adenylsuccinate lyase deficient mutant. PMID- 4215290 TI - Study of lysogenic Bacillus cereus strains by electron microscopy. PMID- 4215291 TI - A highly specific phage attacking Bacillus anthracis strain Sterne. PMID- 4215292 TI - Bacteriological and pharmacological investigations with Garamycin (gentamicin). PMID- 4215293 TI - Study of auxotroph mutants induced by copper sulphate in Bacillus subtilis. PMID- 4215294 TI - Bacterial contamination and sparing heat treatment of mother's milk. PMID- 4215295 TI - Topologic analysis of the fate of transfecting SP50 DNA in competent cells of Bacillus subtilis. PMID- 4215296 TI - Pirazocillin: a new acid and penicillinase resistant semisynthetic penicillin. PMID- 4215297 TI - [A case of Pringle-Bourneville disease associated with neurofibromatosis]. PMID- 4215298 TI - 13C NMR studies of the interaction of Hb and carbonic anhydrase with 13Co2. PMID- 4215299 TI - Physicochemical studies of Ca++ controlled antigen antibody systems. PMID- 4215300 TI - The functional roles of metals in metalloenzymes. PMID- 4215301 TI - The application of perturbed directional correlation of gamma rays to the study of protein-metal interactions. PMID- 4215302 TI - Nutrition and malnutrition. Identification and measurement. Definition of the problem. PMID- 4215303 TI - Anthropometry as an index of nutritional status. PMID- 4215304 TI - From a QUAC stick to a compositional assessment of man's nutritional status. PMID- 4215305 TI - Relative values of longitudinal, cross-sectional and mixed data collection in community studies. PMID- 4215306 TI - Ecological factors relating to child growth and nutritional status. PMID- 4215307 TI - Behavioral effects of artificial gravity: equivalence of rotation rate and radius in controlling gravity-avoidance behavior. PMID- 4215308 TI - Coprophagy in laboratory animals: a preliminary study to assess potential influences of excreta ingestion on radionuclide retention patterns. PMID- 4215309 TI - Letter: Heat stability of serum pyridoxal. PMID- 4215310 TI - A comparison of methods for estimating human body composition. PMID- 4215312 TI - A new method for determination of alpha-1-antitrypsin phenotypes using isoelectric focusing on polyacrylamide gel slabs. PMID- 4215311 TI - Special problems associated with the isolation and identification of intestinal bacteria in fecal flora studies. PMID- 4215313 TI - Demonstration of IgE on human-skin mast cells using anti-IgE125I and refined light microscopy. PMID- 4215314 TI - Effect of incubation time on Lactobacillus casei bioassay. Variation with two different commercial assay media. PMID- 4215315 TI - Parenteral hyperalimentation--Five years' clinical experience. PMID- 4215316 TI - Letter: Trace element requirements in hyperalimentation. PMID- 4215317 TI - Letter: Stability of phytonadione in hyperalimentation fluids. PMID- 4215318 TI - Correlation of low serum IgM levels with absence of functional splenic tissue in sickle cell disease syndromes. PMID- 4215319 TI - Discoid lupus erythematosus with macroglobulinemia. Correlations between autoimmunity and B cell malignancy with hyperimmunoglobulinemia. PMID- 4215320 TI - Arthritis in acute hepatitis and chronic active hepatitis. Pathology of the synovial membrane with evidence for the presence of Australia antigen in synovial membranes. PMID- 4215321 TI - Familial myeloma. Report of eight families and a study of serum proteins in their relatives. PMID- 4215322 TI - Epidemic viral hepatitis, type B, in hospital personnel. PMID- 4215324 TI - Crisis intervention for ghetto children: contraindications and alternative considerations. PMID- 4215323 TI - Auto-immune hemolytic anemia. PMID- 4215325 TI - Time course of isotonic contraction in single cells and muscle strips from Bufo marinus stomach. PMID- 4215326 TI - Absence of edge damage in toad urinary bladder. PMID- 4215327 TI - Effects of stimulus conditions, temperature, and length on energy output of frog and toad sartorius. PMID- 4215328 TI - Letter: Dominance, sexual preference, and sexism. PMID- 4215329 TI - Influence of fractionation on acute and late reactions in vocal cord carcinoma. AB - Four schedules for the treatment of localized vocal cord carcinoma were compared, to establish a relationship between daily and total dose, and acute and late normal tissue reactions. All patients were treated 5 days per week. All of those who received 200 R daily (6,000 R in 30 treatments) developed a confluent mucositis and minimal to moderate subsequent aryepiglottic edema. Patients who received 180 R daily (6,480 R in 36 treatments) developed a patchy mucositis. Those who received 170 R daily (7,140 R or 6,400 rads in 42 treatments) developed only a brisk erythema, with decreasing incidence and severity of edema. At 160 R daily (6,880 R in 43 treatments) only a mild erythema developed, with no visible edema at any time. Local recurrence rates of about 10 percent for T1 lesions, and of about 25 per cent for T2 and T3 lesions, indicate that the decrease in reactions with longer fractionation has been achieved without loss of tumor control. Even minimal improvement in functional status following treatment for this highly curable malignancy well justifies the inconvenience of the increased number of treatments. The present formula of Ellis for normal tissue tolerance is not consistent with these findings, since the NSDs are essentially identical for all 4 schedules, while tolerance is notably improved by increasing fractionation. PMID- 4215330 TI - Kaposi's sarcoma. Experience with ten cases. AB - Kaposi's sarcoma is uncommon in the U.S.A. and common in Africa. Men are affected at least 4 times more frequently than females. It occurs simultaneously with lymphomas and resembles them in several ways. Radiation therapy controls the disease well. Ten patients were seen with the disease. Most had a relatively benign course, especially the 4 women. Treatment with supervoltage irradiation and cryosurgery was effective in controlling local disease. PMID- 4215331 TI - Computer generated isodose curves for high energy x-ray machines. Experimental verification and time-saving strategies. AB - Calculation of isodose patterns for high energy therapy units using Cunningham's BEAM program requires accurate information on the beam profile in air. This may be obtained by scanning across the x-ray beam using a very small silicon diode detector. Data obtained on a particular unit may not be applicable to any other unit. Computer calculations of isodose curves for high energy x-ray machines must use a 0.25 cm. or smaller lateral grid of dose calculation points to ensure accurate reproduction of the sharp fall-off of the dose at the beam edge. Computer calculation time to obtain the isodose curves using this size lateral grid is prohibitively long. The computing time can be appreciably reduced by: (1) changing the width of the annular sectors used in calculating the contribution of scattered radiation to the dose to 0.5 cm.; and (2) calculating the dose at 0.25 cm. lateral intervals within 1 cm. of the beam edge, but changing the spacing of the grid to 1 cm. inside the field. These programming strategies do not produce any significant change in the isodose curves but lead to a significant reduction in computer time. PMID- 4215332 TI - Design of X-ray targets for high energy linear accelerators in radiotherapy. PMID- 4215333 TI - Angiographic features of arterial lesions in neurofibromatosis. PMID- 4215334 TI - Schistosoma mansoni circulating antigen: detection by complement fixation in sera from infected hamsters and mice. PMID- 4215335 TI - Late assessment of results of cricopharyngeal myotomy for cervical dysphagia. PMID- 4215336 TI - Use of tobramycin in eradicating experimental bacterial endophthalmitis. PMID- 4215337 TI - Pyrexia following open heart surgery. The role of bacterial infection. PMID- 4215338 TI - Removal of proteases from DNase I by chromatography over agarose with covalently attached lima bean protease inhibitor. PMID- 4215339 TI - Anomalous behaviour of EDTA during gel filtration. Studies on the possible contamination of the S100 protein. PMID- 4215341 TI - Synthesis of the active derivative of bovine trypsin-kallikrein inhibitor (Kunitz) with open peptide bond in the reactive site. PMID- 4215340 TI - The determination of chlorine in organic materials by combustion and microcoulometry. PMID- 4215342 TI - Proteinase catalyzed resynthesis of the peptide bond Lys 15--Ala 16 in the derivative of trypsin-kallikrein inhibitor (Kunitz) with this peptide bond hydrolyzed. PMID- 4215343 TI - Replacement of lysine by arginine, phenylalanine, and tryptophan in the reactive site of the trypsin-kallikrein inhibitor (Kunitz). PMID- 4215344 TI - Inactivation of the trypsin-kallikrein inhibitor (Kunitz) by cleavage of the dipeptide Ala 16--Arg 17 in the reactive site. PMID- 4215345 TI - Evaluation of agar gel immunodiffusion for detection of immunologic response of pigs to experimental infection with hemagglutinating encephalomyelitis virus. PMID- 4215346 TI - Intestinal absorption of D-xylose and folic acid measured by a perfusion technique in patas monkeys (Erythrocebus patas). PMID- 4215347 TI - Epidemiologic studies relating thermophilic fungi and hypersensitivity lung syndromes. PMID- 4215348 TI - The purification of mycobacterial polysaccharides with concanavalin A. PMID- 4215349 TI - Letter: The impact of chemotherapy on the care of patients with tuberculosis. PMID- 4215350 TI - Active and passive immunization in the treatment of experimental burn wound sepsis from Pseudomonas. PMID- 4215351 TI - Group-y meningococcal disease. Twelve cases at an army training center. PMID- 4215352 TI - Treatment of diphtheria carriers: benzathine penicillin, erythromycin, and clindamycin. PMID- 4215353 TI - Letter: Variant anginal syndrome, coronary artery spasm, and ventricular fibrillation in absence of chest pain. PMID- 4215354 TI - [Discharge from the psychiatric hospital after a hospitalization period extending beyond 10 years]. PMID- 4215355 TI - Comparative structure of myoglobin: primates and tree-shrew. PMID- 4215356 TI - Multiple hemoglobin alpha-chain loci in monkeys, apes, and man. PMID- 4215357 TI - Rodent hemoglobin structure: a comparison of several species of mice. PMID- 4215358 TI - Exploratory studies on detection of hemoglobins in the early human fetus in utero. PMID- 4215359 TI - Effects of membrane potential on sodium and potassium fluxes in squid axons. PMID- 4215360 TI - A delayed side effect of topical thiotepa. PMID- 4215361 TI - [Analysis of the temporal trend of antibody titer after delivery in subjects with anti-Rh (D) isoimmunization]. PMID- 4215362 TI - A reference blood as a control of parameters in Coulter S. PMID- 4215363 TI - Clinical diagnosis of the monoclonal gammopathies. PMID- 4215364 TI - Space microbiology. PMID- 4215365 TI - Viroids: the smallest known agents of infectious disease. PMID- 4215366 TI - Persisting bacteriophage infections, lysogeny, and phage conversions. PMID- 4215367 TI - Virus-induced modification of cellular membranes related to viral structure. PMID- 4215368 TI - Mechanisms of inorganic oxidation and energy coupling. PMID- 4215369 TI - [Healthy carriers of meningococci. Study of a group of families]. PMID- 4215370 TI - An immunological and electrophoretic study of Rhodospirillum rubrum chromatophore fragments. PMID- 4215371 TI - Calorimetric measurement of the enthalpy of magnesium binding to yeast enolase. PMID- 4215372 TI - Proceedings: Parenteral feeding: metabolic changes. PMID- 4215373 TI - Proceedings: Parenteral feeding: surgical indications and techniques. PMID- 4215374 TI - Proceedings: Use of diphosphonates in diseases associated with ectopic calcification. PMID- 4215375 TI - Polychlorinated biphenyls. Storage, distribution, excretion, and recovery: liver morphology after prolonged dietary ingestion. PMID- 4215376 TI - [Immunotaxonomic study of the genus Naegleria]. PMID- 4215377 TI - Disseminated toxoplasmosis in the compromised host. A report of five cases. PMID- 4215378 TI - Atherosclerotic coronary artery aneurysm. Report of five cases and review of literature. PMID- 4215379 TI - Prolonged trance-like stupor in epilepsy. Petit mal status-wave stupor, spaced out status. PMID- 4215380 TI - Gonococcal lymphadenitis. PMID- 4215382 TI - [1st derivative of the carotid pulse in orificial aortic stenosis]. PMID- 4215381 TI - [Angina with normal coronarography. Cardiac hemodynamics and metabolism of 3 patients]. PMID- 4215383 TI - [Coronary vessel perfusion in aortic and multiple valve replacement surgery: Incidences on postoperative mortality and morbidity]. PMID- 4215384 TI - [1033 primo-implantations of cardiac pacemakers. Comparative advantages and disadvantages of epigastric and endocavitary approaches]. PMID- 4215385 TI - [Traumatic injury of right heart. Apropos of a case with tricuspid valve insufficiency and right ventricle aneurysm]. PMID- 4215386 TI - [Contribution of mechanograms in the assessment of tricuspid insufficiencies with or without surgical valve correction]. PMID- 4215387 TI - [Correlations between the jugulogram, right ventricular systolic pressure and pulmonary artery pressure]. PMID- 4215388 TI - [Quantitative angiographic assessment of left ventricular kinetics and volumes: a critical study]. PMID- 4215390 TI - [Prevention of pulmonary embolism by insertion of an umbrella filter in the inferior vena cava]. PMID- 4215389 TI - [The computer in intensive care units]. PMID- 4215391 TI - [Electrocardiographic aspects suggessive of Prinzmetal's angina with normal coronary arteries at autopsy]. PMID- 4215392 TI - [In memoriam: Edmond Henry]. PMID- 4215393 TI - [Study of cardiac hemodynamics and metabolism in normal and coronary patients]. PMID- 4215394 TI - One-step isolation of microbial ribulose-1,5-diphosphate carboxylase. PMID- 4215395 TI - Estimation of the genome size of blue-green algae from DNA renaturation rates. PMID- 4215396 TI - Studies on gliding motility in Myxococcus xanthus. PMID- 4215397 TI - [Metabolic products of microorganisms. 134. Stenothricin, a new inhibitor of the bacterial cell wall synthesis (author's transl)]. PMID- 4215398 TI - [Serum levels of alpha-1 antitrypsin in chronic bronchopathies]. PMID- 4215399 TI - [Quantitative immunological determination of antithrombin III concentration during normal pregnancy and post partum (author's transl)]. PMID- 4215400 TI - Immunochemical determination of human pregnancy proteins. PMID- 4215401 TI - Distribution of gastrin in human digestive organs demonstrated by direct immunofluorescence. PMID- 4215402 TI - [Effect of epileptic seizures on the composition of the cerebrospinal fluid (author's transl)]. PMID- 4215403 TI - Nursing care of the patient being maintained on long-term peritoneal dialysis. PMID- 4215404 TI - [Changes in the follicular epithelium in the course of oogenesis in some amphibians]. PMID- 4215405 TI - Retina and optic nerve after posterior ciliary artery occlusion. An experimental study in squirrel monkeys. PMID- 4215406 TI - Effect of lidocaine on the antibacterial activity of seven antibiotics. PMID- 4215407 TI - Ocular manifestations of Conradi disease. PMID- 4215408 TI - TheThe genetic architecture of resistance to desiccation in populations of Drosophila melanogaster and D. simulans. PMID- 4215409 TI - Drinks, drugs - the doctor's dilemma. PMID- 4215410 TI - A new look at an age old problem. PMID- 4215411 TI - Avian infectious bronchitis: demonstration of serum IgG- and IgM-neutralizing antibody by sucrose density-gradient centrifugation and mercaptoethanol reduction. PMID- 4215412 TI - Virucidal activity of commercial disinfectants against velogenic viscerotropic Newcastle disease virus. PMID- 4215413 TI - Preprogrammed and feedback-guided movements of monkeys. PMID- 4215414 TI - Genetic control of activity, preening, and the response to a shadow stimulus in Drosophila melanogaster. PMID- 4215415 TI - Recommended methods used in the nutritional status assessment: clinical signs and symptoms. PMID- 4215416 TI - Reasons for, and methods in dietary and food consumption surveys. PMID- 4215417 TI - Genetics of esterases in Drosophila. III. Influence of different chromosomes on esterase pattern in Drosophila. PMID- 4215418 TI - Rabbit beta-glucuronidase. Purification and properties, and the existence of multiple forms. AB - 1. beta-Glucuronidase (EC 3.2.1.31) was purified from rabbit liver by a procedure involving autolysis, (NH(4))(2)SO(4) fractionation, chromatography on DEAE cellulose and hydroxyapatite, gel filtration, sedimentation in a sucrose gradient, and isoelectric focusing. 2. Electron microscopy revealed ferritin as the major contaminant in later stages of purification and also showed aggregates of enzyme molecules. Particular attention was paid to the removal of ferritin. 3. The purified enzyme was homogeneous in polyacrylamide-gel electrophoresis both in non-dissociating conditions and in the presence of sodium dodecyl sulphate, and in Ouchterlony gel diffusion and immunoelectrophoresis against polyspecific antisera. 4. Sedimentation in sucrose gradients gave a molecular weight of 300000, whereas gel filtration indicated 440000. 5. Subunits of 75000 molecular weight were observed in gel electrophoresis in the presence of sodium dodecyl sulphate and in gel filtration in the presence of urea. 6. The K(m) value for p nitrophenyl beta-d-glucuronide was 0.6mm, and the enzyme was extremely sensitive to lactone inhibitors. It was also inhibited by Hg(2+) ions. 7. Multiple forms were observed in the pure enzyme by isoelectric focusing, with pI values of 4.5 5.8. Subunits showed similar heterogeneity. The origin of the multiple forms was investigated in detail, and the possibility of artifact generation largely excluded. Some of the forms of lowest pI disappeared after neuraminidase digestion. The nature of the residual heterogeneity remains to be elucidated. PMID- 4215420 TI - Maroteaux-Lamy disease (mucopolysaccharidosis VI), subtype A: deficiency of a N acetylgalactosamine-4-sulfatase. PMID- 4215421 TI - Change of enzyme activities during the early stage of influenza virus infection. PMID- 4215419 TI - Rabbit beta-glucuronidase. Subcellular distribution and immunochemical properties. AB - 1. The subcellular distribution of beta-glucuronidase and other hydrolases in rabbit liver was investigated. beta-Glucuronidase was found in both microsomal and lysosomal fractions. 2. Multiple forms of beta-glucuronidase were present in extracts of microsomal and lysosomal fractions. All forms were common to both fractions. 3. A specific antiserum against beta-glucuronidase was raised, and characterized by immunoprecipitation and affinity-chromatography procedures. 4. The immunological identity of the multiple forms in the pure beta-glucuronidase preparation, and the immunological identity of the beta-glucuronidase complement of lysosomal extracts with that of microsomal extracts, were demonstrated by means of the antiserum. The presence of inactive enzyme in various enzyme preparations was shown. PMID- 4215422 TI - Chelation of divalent cations by lomofungin: role in inhibition of nucleic acid synthesis. PMID- 4215424 TI - Monoamine oxidase inhibitors and other drugs as inhibitors of diamine oxidase from human placenta and pig kidney. PMID- 4215423 TI - Structure-activity relationships in the effects of 1-alkylimidazoles on microsomal oxidation in vitro and in vivo. PMID- 4215426 TI - Letter: Serum gold determinations. PMID- 4215425 TI - Clinical features and serologic abnormalities in juvenile rheumatoid arthritis. PMID- 4215427 TI - Letter: Long-term side effects of azathioprine. PMID- 4215428 TI - Qualitative characteristics of anti-DNA antibodies in lupus nephritis. PMID- 4215429 TI - Immunoglobulin E (IgE) levels in serum and synovial fluid in rheumatoid arthritis. PMID- 4215430 TI - 7-nitro-8-acyloxyquinolines with antimicrobial and antifungal activity. PMID- 4215431 TI - [Studies in the rat on absorption, distribution and excretion of penicillin V. I. Studies of balance]. PMID- 4215432 TI - [Results of treatment of male fertility disorders with mesterolone or a placebo]. PMID- 4215433 TI - Antimicrobial studies in vitro with cephacetrile, a new cephalosporin derivative. PMID- 4215434 TI - Pharmacokinetic studies in animals and humans of a new cephalosporin, the sodium salt of 7-cyanacetyl-amino-cephalosporanic acid. PMID- 4215436 TI - Experimental pseudomonas osteomyelitis: treatment with sisomicin and carbenicillin. PMID- 4215435 TI - Effect of diet on hepatic and intestinal lipogenesis in squirrel, cebus, and cynomolgus monkeys. PMID- 4215437 TI - [Intestinal capacity for absorbing D-xylose in patients of pediatric age]. PMID- 4215438 TI - [Practical method of parenteral nutrition for pediatric use]. PMID- 4215439 TI - [Hereditary atransferrinemia]. PMID- 4215440 TI - [Chronic toxicity of bufexamac in the rat and monkey]. PMID- 4215441 TI - Proceedings: Postoperative measurement of blood flow in saphenous vein bypass grafts. PMID- 4215442 TI - Investigation of mechanisms of action of anti-tumour factors made from lymph nodes or spleens of allergized allogeneic mice. PMID- 4215443 TI - Intracellular killing of different strains of Pseudomonas aeruginosa by human leucocytes. PMID- 4215444 TI - Vaccine potencies of the live vaccine strain of Francisella tularensis and isolated bacterial components. PMID- 4215445 TI - Hepatocellular uptake of ferritin in the rat. PMID- 4215446 TI - Plant carbonic anhydrase. Hydrase activity and its reversible inhibition. PMID- 4215447 TI - Studies on interaction between poly(L-lysine 40, L-alanine 60) and deoxyribonucleic acids. PMID- 4215448 TI - Synthesis of oligodeoxyribonucleotide ethyl phosphotriesters and their specific complex formation with transfer ribonucleic acid. PMID- 4215449 TI - The identification of poly-gamma-glutamyl chain lengths in bacterial folates. PMID- 4215450 TI - Factors involved in the synthesis of cyclopropane fatty acids by Streptococcus faecalis. PMID- 4215451 TI - Physiological differences between cyclopropane fatty acid-deficient mutants and the parent strain of Streptococcus faecalis. PMID- 4215452 TI - Physical properties and biological activities of two forms of alpha-N acetylglucosaminidase from bovine spleen. PMID- 4215453 TI - Further characterization of human thyroxine-binding globulin. PMID- 4215454 TI - Legume root nodule nitrogenase. Purification, properties, and studies on its genetic control. PMID- 4215455 TI - Activation of platelet fibrin-stabilizing factor by thrombin. PMID- 4215456 TI - Amino acid sequence of sheep carbonic anhydrase C. PMID- 4215457 TI - SomeSome characteristics of a phospholipase A2 from sheep red cell membranes. PMID- 4215459 TI - Genetic complexity of mitochondrial DNA from Euglena gracilis. PMID- 4215458 TI - Lecithinase activities at the external surface of ruminant erythrocyte membranes. PMID- 4215460 TI - Properties of mitochondrial DNA from Kluyveromyces lactis. PMID- 4215461 TI - The attachment of polyribosomes to membranes of the hypocotyl of Phaseolus vulgaris. PMID- 4215462 TI - Solubilization and properties of poly(ADP-ribose) polymerases from bovine spleen and Ehrlich ascites cells. PMID- 4215463 TI - Size and configuration of mitochondrial DNA in Euglena gracilis. PMID- 4215464 TI - Subunit structure of DNA-dependent RNA polymerase of Anacystis nidulans. PMID- 4215465 TI - [Letter: Kinetics of energy-dependent exchange of H+ and K+ in Streptococcus faecalis]. PMID- 4215467 TI - [Comparative study of 2 direct methods for the radioimmunologic determination of carcinoembryonic antigen]. PMID- 4215466 TI - [Effect of deoxycholate on lipid peroxidation in liver microsomes]. PMID- 4215468 TI - [Effect of caffeine and acriflavine on the survival of ultraviolet irradiated cyanophage AM-1 in the cells of radiosensitive mutants of Anacystis nidulans]. PMID- 4215469 TI - Loss of cellular material from suspensions of isolated epithelial cells of guinea pig small intestine. PMID- 4215470 TI - [A molecular disease: hereditary angioneurotic edema. Study of 16 families]. PMID- 4215471 TI - Anti-h absorbed by, and eluted from Oh (Bombay) red blood cells. PMID- 4215472 TI - Effect of metal binding on the intrinsic fluorescence of bovine carbonic anhydrase. PMID- 4215473 TI - Two proposed general configurations for bacterial cell wall peptidoglycans shown by space-filling molecular models. PMID- 4215474 TI - Qualitative and quantitative mass spectrometry of some noncatecholic biogenic amines and related compounds as their dansyl derivatives. PMID- 4215475 TI - Treatment related observations in solid tissues, fibroblast cultured and amniotic fluid cells of type II glycogenosis, Hurler disease and metachromatic leukodystrophy. PMID- 4215476 TI - Enzyme replacement in genetic disease. Prospectus. PMID- 4215477 TI - Mucopolysaccharide-storage diseases: corrective activity of normal human serum and lymphocyte extracts. PMID- 4215478 TI - Fabry disease: kidney transplantation as an enzyme replacement technic. PMID- 4215479 TI - Fabry disease: correction of the enzymatic deficiency by renal transplantation. PMID- 4215480 TI - Enzyme replacement in Fabry disease: treatment of cultured skin fibroblasts with a purified alpha-galactosidase from ficin. PMID- 4215481 TI - [State of the histamine-histaminase system in the diagnosis of traumatic shock]. PMID- 4215482 TI - [Quantitative relations existing between the mass of the primary ureter and the inductive action produced by it on the mesonephrogenic blastema of anouran amphibians]. PMID- 4215483 TI - [Relative importance of the mating stimulations: courtship, copulation and insemination on the ovarian production of Drosophila melanogaster]. PMID- 4215484 TI - [Influence of genetic structure of a population on its sensitivity to consanguinity]. PMID- 4215485 TI - Distribution of polychlorinated biphenyls in an aerated biological oxidation wastewater treatment system. PMID- 4215486 TI - Polychlorinated biopenyls. V. Synthesis of 14C-labelled 2,2', 4,4',5,5' hexachlorobiphenyl, a major component in PCB-mixtures. PMID- 4215487 TI - Effects of dieldrin and PCB's upon the production and morphology of Japanese quail eggs. PMID- 4215488 TI - Recovery of trichlorfon (Dylox) and carbaryl (Sevin) in songbirds following spraying of forest for gypsy moth. PMID- 4215489 TI - Analyses of polychlorinated biphenyls in bird tissues and Aroclor standards with gas chromatography and mass spectrometry. PMID- 4215490 TI - Interference in the electron-capture technique for determination of polychlorinated biphenyls by sulfur-containing compounds in petroleum products. PMID- 4215491 TI - DDT, DDE and PCBs in the tissues of reef dwelling groupers (Serranidae) in the Gulf of Mexico and the Grand Bahamas. PMID- 4215492 TI - PCB'S and p,p' DDE in the blood of cachectic patients. PMID- 4215493 TI - Time-course of induction of microsomal enzymes following treatment with polychlorinated biphenyl. PMID- 4215494 TI - Comparison of polychlorinated biphenyls in yusho patients and ordinary persons. PMID- 4215495 TI - Dissipation of Guthion Sevin, Polyram, Phygon and Systox from apple orchard soil. PMID- 4215496 TI - Bacterial degradation of polychlorinated biphenyls. I. Identification of some metabolic products from Aroclor 1242. PMID- 4215497 TI - Accumulation of Aroclor 1254 in grass shrimp (Palaemonetes pugio) in laboratory and field exposures. PMID- 4215498 TI - Gas chromatography and mass spectrometry of polychlorinated terphenyls (Aroclor 5460). PMID- 4215499 TI - Effect of aflatoxin B1, ochratoxin and rubratoxin B on a protozoan, Tetrahymena pyriformis HSM. PMID- 4215500 TI - DDE, PCB and aldrin levels in Arctic birds of Greenland. PMID- 4215501 TI - A gas chromatographic-mass spectrometric comparison of polychlorinated biphenyl residues in the Japanese quail brain to an Aroclor standard. PMID- 4215503 TI - High-volume collection of atmospheric polychlorinated biphenyls. PMID- 4215502 TI - Polychlorinated biphenyls and p,p' DDE in green turtle eggs from Ascension Island, South Atlantic Ocean. PMID- 4215504 TI - Embryotoxic and teratogenic effects in unhatched fertile eggs from hens fed polychlorinated biphenyls (PCBs). PMID- 4215505 TI - Effects of nonpersistent pesticides on liver weight, lipids and vitamin A of rats and quail. PMID- 4215506 TI - Chlorinated insecticide residues in the eggs of some freshwater fish. PMID- 4215507 TI - Uptake of a PCB (Aroclor 1254) from soil by carrots under field conditions. PMID- 4215508 TI - Effect of diethylstilbestrol on feedlot associated bacteria. PMID- 4215509 TI - Translocation of four organochlorine compounds by red mangrove (Rhizophora mangle L.) seedlings. PMID- 4215510 TI - Gas-liquid chromatography--mass spectrometric characterization of aroclor 1242 and 1254 components. PMID- 4215511 TI - The effect of age and sex on the toxicity of Aroclor 1254, a polychlorinated biphenyl, in the rat. PMID- 4215512 TI - Mercury and selected pesticide levels in fish and wildlife of Utah: II. Levels of mercury, DDT, DDE, dieldrin and PCB in chukars, pheasants and waterfowl. PMID- 4215513 TI - Acute effects of Aroclor 1254 (PCB) on Ictalurus punctatus (catfish). PMID- 4215514 TI - Mercury and selected pesticide levels in fish and wildlife of Utah: I. Levels of mercury, DDT, DDE, dieldrin and PCB in fish. PMID- 4215515 TI - Avoidance of Aroclor 1254 by shrimp and fishes. PMID- 4215516 TI - Presence of PCB, DDE and DDT in human milk in the provinces of New Brunswick and NOVA Scotia, Canada. PMID- 4215517 TI - Efficacy of home laundering in removal of DDT, methyl parathion and toxaphene residues from contaminated fabrics. PMID- 4215518 TI - Some aspects of the recovery of chlorinated residues (DDT-type compounds and PCB) from fish tissue by using different extraction methods. PMID- 4215519 TI - The finding of chlorinated dibenzofurans in a Japanese polychlorinated biphenyl sample. PMID- 4215520 TI - Effect of PCB ingestion on sleeping times, organ weights, food consumption, serum corticosterone and survival of albino mice. PMID- 4215521 TI - Uptake of chlorinated paraffins and PCB from suspended solids and food by juvenile Atlantic salmon. PMID- 4215522 TI - Polychlorinated biphenyl emission from fluorescent lamp ballasts. PMID- 4215523 TI - Reduction of pentobarbital-induced sleeping times in PCB-treated cottontail rabbits. PMID- 4215524 TI - Metabolism of 2,2'-dichlorobiphenyl-14C in two plant-water-soil-systems. PMID- 4215525 TI - Residues of organochlorine insecticides and PCBs in samples of Norwegian butter 1966-1972. PMID- 4215526 TI - The use of polyurethane foam plugs for extraction of polychlorinated biphenyls (PCB's) from natural waters. PMID- 4215527 TI - The teeth of hominids, hominoids and pongids. PMID- 4215528 TI - Jacksonian seizure arising from the contralateral hippocampus. PMID- 4215529 TI - The relative effectiveness of super- and orthovoltage x rays for intestinal damage in man and mouse: an apparent discrepancy and its explanation. PMID- 4215530 TI - Relative biological effectiveness (RBE) of 30 MeV electrons at varying depths in tissue. PMID- 4215531 TI - Letter: SI Units in radiology. PMID- 4215532 TI - Comparative radiobiological measurements with two high-energy cyclotron-produced neutron beams presently used for radiotherapy. PMID- 4215533 TI - Letter: Recent advances in the development of a 14 MeV neutron generator suitable for radiotherapy. PMID- 4215534 TI - Total body potassium in long-term frusemide therapy: is potassium supplementation necessary? AB - Measurements of total body potassium (T.B.K.) were made by whole-body counting in four groups of patients receiving oral frusemide for one year. Patients in group 1 had essential hypertension and normal renal function and received 40 mg frusemide daily without potassium supplements. Patients in group 2 were similar but received oral potassium supplements for the first four months of treatment. Patients in group 3 had hypertension associated with renal disease and received 120 mg frusemide daily without potassium supplements. Patients in group 4 also had hypertension and renal impairment and in addition to 120 mg frusemide daily they received oral potassium supplements for four months. No evidence of depletion of T.B.K. was found in any of the groups after continuous treatment with frusemide for one year. It is questioned whether potassium supplementation in long term diuretic therapy with frusemide is necessary unless there is evidence of pre-existing potassium depletion or of some other factor such as cardiac failure, cirrhosis of the liver, or the nephrotic syndrome. PMID- 4215535 TI - Letter: Two-phase blood culture system. PMID- 4215536 TI - Absorption of slow-release iron and effects of ascorbic acid in normal subjects and after partial gastrectomy. AB - Radiolabelled tablets of slow-release iron and ferrous sulphate containing 50 mg of elemental iron were given to 28 patients, and iron absorption was studied using a whole body counter.There was no significant difference between the absorption of ferrous sulphate and that of slow-release iron in normal subjects, anaemic patients, anaemic and non-anaemic post-gastrectomy patients, or those with coeliac disease. Ascorbic acid potentiated iron absorption, especially in anaemic post-gastrectomy patients.The indications and hazards of slow release iron preparations are discussed. PMID- 4215537 TI - Letter: Gianotti-Crosti syndrome and viral infection. PMID- 4215538 TI - Editorial: Medical nemesis. PMID- 4215539 TI - Medical Nemesis--three views. "Medicalization" of health. PMID- 4215540 TI - Medical nemesis--three views. Indictment of medical care. PMID- 4215541 TI - Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations of blunt head injuries. PMID- 4215542 TI - A crescent-shaped cortical visual area surrounding the middle temporal area (MT) in the owl monkey (Aotus trivirgatus). PMID- 4215543 TI - Choline acetyltransferase localization in the central nervous system by immunohistochemistry. PMID- 4215544 TI - Catecholamine-binding protein in mouse brain: isolation and characterization. PMID- 4215545 TI - On the elicitability of vocalization from the cortical larynx area. PMID- 4215546 TI - [Rehabilitation and physical therapy of the nonsenile hemiplegic. Considerations on the differentiation of the neuro-anatomic prehensile apparatus in primates and therapeutic implications in the rehabilitation of non senile hemiplegia]. PMID- 4215547 TI - [Contribution of immunology to clinical diagnosis]. PMID- 4215548 TI - [Quantitative rheographic study of the effects of a new drug combination: raubasine/dihydroergocristine]. PMID- 4215549 TI - Directed mutation in Streptomyces lipmanii. PMID- 4215550 TI - Purification of Rickettsia rickettsi by density-gradient zonal centrifugation. PMID- 4215551 TI - Action of streptomycin on the growth of Streptomyces griseus. PMID- 4215552 TI - Growth abnormalities in microorganisms exposed to tobacco leaf extracts. PMID- 4215553 TI - Minicell formation in chloramphenicol-treated Bacillus cereus. PMID- 4215554 TI - Localization of neuroendocrine functions within the hypothalamus. PMID- 4215555 TI - Role of the ventricular system in neuroendocrine processes: synthesis and distribution of thyrotropin releasing factor (TRF) in the hypothalamus and third ventricle. PMID- 4215557 TI - Letter: Rh sensitization following abortion. PMID- 4215556 TI - Myasthenia gravis associated with diphenylhydantoin therapy for epilepsy. PMID- 4215558 TI - The effect of dexamethasone on TSH and prolactin secretion after TRH stimulation. AB - Serum thyrotropin (TSH) and prolactin levels were measured after intravenous administration of 400 mug of synthetic thyrotropin-releasing hormone (TRH) in 13 normal subjects and six hypothyroid patients before and after three days of administration of dexamethasone 2 mg per day. In the normal subjects dexamethasone suppressed baseline serum levels and secretion of TSH after TRH stimulation. On the other hand, it had no effect on the hypothyroid patients. In the control group dexamethasone also suppressed baseline serum levels but not secretion of prolactin after TRH stimulation. Dexamethasone had no effect on prolactin levels in the hypothyroid group. It is concluded that in normal patients short-term administration of dexamethasone has an inhibitory effect on TSH secretion at the pituitary level. As for prolactin, our results could indicate that TRH is a more potent stimulator of prolactin secretion than of TSH secretion, or that TSH and prolactin pituitary thresholds for TRH are different. PMID- 4215559 TI - Comparison of amoxicillin and ampicillin in single-dose oral treatment of males with gonococcal urethritis. AB - Amoxicillin in single oral doses of 2.0 g, 2.0 g plus 1.0 g probenecid, or 3.0 g was compared with ampicillin 3.5 g plus 1.0 g probenecid in the treatment of 203 males with uncomplicated acute gonococcal urethritis. Cure rates above 95% were produced by all treatments except the 2.0-g amoxicillin dose, which cured 89% of patients. Of 198 pretreatment gonococcus isolates tested by an agar dilution technique for susceptibility to penicillin G, ampicillin and amoxicillin, over 50% showed relative resistance (MIC > 0.06 mug/ml) to the antibiotics. However, amoxicillin was somewhat more active against isolates showing considerable resistance (MIC >/= 1.0 mug/ml) to penicillin G or ampicillin. Adverse effects of amoxicillin were few: two patients reported transient nausea and six noted short lived diarrhea. No hypersensitivity reactions were observed. PMID- 4215560 TI - Nursing needs of ambulatory patients with chronic disease. PMID- 4215561 TI - Radiotherapy for carcinoma of the cervix recurrent after surgery. PMID- 4215562 TI - Coronary collateral flow following acute coronary occlusion: a diastolic phenomenon. PMID- 4215563 TI - [Parenteral nutrition, theory and practice. Amino acids, fats, vitamins (author's transl)]. PMID- 4215564 TI - [Endotoxin shock and tetracycline antibiotics (author's transl)]. PMID- 4215565 TI - [Micromethod for thromboagglutinins and erythrocyte antigens assay (author's transl)]. PMID- 4215566 TI - [Immunoglobulins in infective hepatitis (author's transl)]. PMID- 4215567 TI - [Purulent thrombophlebitis (author's transl)]. PMID- 4215568 TI - [Prolactin (author's transl)]. PMID- 4215569 TI - [Antitubercular agents. XV. Use of HMO calculations in the study of structure activity relationship of antitubercular agents. II]. PMID- 4215570 TI - [Metabolism of steroids in the CNS]. PMID- 4215571 TI - Comparative effects of commercial Aroclors on rat liver enzyme activities. PMID- 4215572 TI - Structure-activity dependence in some novel ring-substituted 3,3-dimethyl-1 phenyltriazenes. Genetic effects in Drosophila melanogaster and in Saccharomyces cerevisiae by a direct and a host-mediated assay. PMID- 4215573 TI - The synthesis of a DOPA analogue, 1-amino-2-(3, 4-dihydroxyphenyl) ethylphosphonic acid and distribution studies in mice bearing the Harding-Passey melanoma. PMID- 4215574 TI - The effect of aflatoxin B, on the maturation of ribosomal and transfer RNA in monkey kidney (CV-1) cells in culture. PMID- 4215575 TI - [Pathology of Oddi's sphincter as related to the latest work on radiologic anatomy]. PMID- 4215576 TI - [The retino-thalamo-hyperstriatal pathway in the chicken (Gallus domesticus L.)]. PMID- 4215577 TI - [Scanning electron microscopy by transmission: its value for tridimensional study of cell organelles]. PMID- 4215578 TI - [Action of beta-ecdysone on the development of larval and imaginal epidermal cell lines, from the abdomen of permanent larva of Ceratitis capitata Wied (Dipt. Trypetidae)]. PMID- 4215579 TI - [Images of phagocytosis of neurosecretory fibers by pituicytes in the chick neurohypophysis]. PMID- 4215580 TI - [Mass spectrometry of permethylated derivatives in the determination of C glycosylfavone structure]. PMID- 4215581 TI - [Inhibition by N-acetyl glucosamine polymers of the lysis activity of lysozymes towards Micrococcus luteus: influence of pH and of ionic strength]. PMID- 4215582 TI - [Some properties of a stable variant of Bacillus thuringiensis (Berliner) resistant to B1 aflatoxin]. PMID- 4215583 TI - [Cercaria of Ribeiroia marini (Faust and Hoffman, 1934), antagonistic trematode of Schistosoma mansoni and inducing castration of the host-mollusca, vector of human schistosomiasis]. PMID- 4215584 TI - [Control of food ingestion by duodenal chemorecptors in ruminants]. PMID- 4215585 TI - [Statistical demonstration of sources of variability common to various physical factors of the environment, affecting the aleatory behavior of avoidance in mouse]. PMID- 4215586 TI - [Fetal and placental growth modifications in the female rabbit, under the influence of ovarian hormones]. PMID- 4215587 TI - [Interfacial chemical and hydrodynamic instabilities]. PMID- 4215588 TI - [Hematopoietic infectious necrosis of Salmonidae: production of circulating interferon after experimental infection of the rainbow trout (Salmo gairdneri)]. PMID- 4215589 TI - [Variations of regenerative potentials as a function of seasons in Nicodrilus giardi (Ribaucourt) (Oligochgeta, Lumbricidae)]. PMID- 4215590 TI - [Comparative toxicity of various pesticides towards two species of Diatoma useful in ostreiculture]. PMID- 4215591 TI - [Analysis of the variability in the productivity of an isolated insect population with restricted resources]. PMID- 4215592 TI - [Demonstration on the surface of the Schistosoma mansoni cercaria of antigen having planorb characteristics]. PMID- 4215594 TI - [L-leucine and L-4-aza-leucine, allosteric effectors of alkaline phosphatasic activity of barley]. PMID- 4215593 TI - [Increased excretion of glucosyl-galactosyl-hydroxylysine in urine during glomerulonephritis with nephrotoxic antibodies in the rat]. PMID- 4215596 TI - [In vitro evaluation of cytotoxic activity of nitrosourea compounds]. PMID- 4215597 TI - Eye abnormalities and skeletal deformities in the Pierre Robin syndrome: a balanced evaluation. PMID- 4215595 TI - [Escherichia coli K 12 mutants, able to grow on methyl-beta-galacturonide: simple constitutive mutants for the synthesis of beta-glucuronidase and double mutants also derepressed for the synthesis of 2 enzymes for glucuronate utilization]. PMID- 4215598 TI - Changes of individual proteins in mother and newborn. PMID- 4215599 TI - [Are penicillins administered during pregnancy harmful to the foetus?]. PMID- 4215601 TI - Study of bile proteins in difuse chronic hepatopathies. PMID- 4215600 TI - [Factors affecting the activity of glycogen synthetase-D phosphatase from dog red skeletal muscle (author's transl)]. PMID- 4215602 TI - Electrophoretic forms of human liver alpha-L-fucosidase and their relationship to fucosidosis (mucopolysaccharidosis F). PMID- 4215603 TI - The molecular nature of alpha-fetoprotein in anencephaly and spina bifida. PMID- 4215604 TI - Biosynthesis of parathyroid hormone. PMID- 4215606 TI - Lack of suppression of certain immunoglobulin-producing lymphocytes in T lymphocyte deficiency. PMID- 4215605 TI - Precipitating anti-adrenal antibodies in Addison's disease. PMID- 4215607 TI - Micrognathia and glossoptosis in the newborn. Surgical tacking of the tongue in small jaw syndromes. PMID- 4215608 TI - Proceedings: Dietary folates and their availability to man. PMID- 4215609 TI - Proceedings: The intracellular pH and potassium content of rabbit cardiac and skeletal muscle in potassium depletion. PMID- 4215610 TI - [Specific myocardiopathy of Waldenstrom's disease]. PMID- 4215611 TI - [Arterial hypertension, renal artery stenosis and neurofibromatosis]. PMID- 4215612 TI - Characterization of a ribonuclease from the hepatopancreas of the queen scallop, Chlamys opercularis. PMID- 4215613 TI - Some biochemical characteristics of the salivary gland products of Macaca irus and Cercopithecus aethiops. PMID- 4215614 TI - The J chain of polymeric immunoglobulins. PMID- 4215615 TI - Phylogenetic aspects of immunoglobulin variable region diversity. PMID- 4215616 TI - mRNA for H and L chains of immunoglobulin: specific control of H-chain production. PMID- 4215617 TI - Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia. PMID- 4215618 TI - Pyrbuterol: a new bronchodilator. Phase I-single dose study. PMID- 4215619 TI - A system for the clinical assessment of the antitussive activity of caramiphen. PMID- 4215620 TI - Hemodynamic effects of ethaverine hydrochloride in patients with peripheral vascular disease. PMID- 4215622 TI - Arterial hypertension northwest Florida public health survey-I. Methodology. PMID- 4215621 TI - Local and systemic effects of beclomethasone inhalation in steroid-dependent asthmatic patients. PMID- 4215623 TI - Comparative bioavailability of doxycycline. PMID- 4215625 TI - [Influence of the struggle between the Confucian and the Legalist schools on traditional Chinese medicine]. PMID- 4215626 TI - [Consolidating development of rural cooperative medical service in the last 7 years]. PMID- 4215624 TI - Hirschsprung's disease: its aetiology, pathogenesis and differential diagnosis. PMID- 4215627 TI - [Epidemiology and etiology of esophageal cancer in North China: a preliminary report]. PMID- 4215628 TI - [Relationship between epithelial dysplasia and carcinoma of the esophagus]. PMID- 4215629 TI - [Factors influencing long term survival after resection of bronchogenic carcinoma; an analysis of 1,118 cases]. PMID- 4215630 TI - [Radiotherapy of nasopharyngeal cancer: comparison between the split dose technic and conventional fractionation technic]. PMID- 4215631 TI - [Antitumor activity of nitrocaphane (AT-1258)]. PMID- 4215632 TI - [Normal body temperature and influencing factors]. PMID- 4215633 TI - [Bacterial count in urinary tract infections and factors influencing the result]. PMID- 4215634 TI - [Histopathologic study of chronic suppurative otitis media]. PMID- 4215635 TI - [Reconstruction of severed ears by implanting cartilage]. PMID- 4215636 TI - [Vitamin K3 in relaxation of ileum spasm in rabbits and clinical treatment of biliary colic in biliary ascariasis]. PMID- 4215637 TI - [Developments in the treatment of complications of neoplastic diseases]. PMID- 4215638 TI - [Clinicopathological discussion: No. 21--fever, cough, phlegm, and recurrent hematemesis and chest pain]. PMID- 4215639 TI - [Letter: Ovulation inhibitors during anticonvulsive therapy?]. PMID- 4215641 TI - Serum and liver lipids in normal baboons: effect of different carbohydrate diets. PMID- 4215640 TI - Prostaglandins: current therapeutic status in obstetrics. PMID- 4215642 TI - [Regional incidence of chronic and recurrent pancreatitis]. PMID- 4215643 TI - The effect of a single large dose of thyrotropin-releasing hormone on various aspects of thyroid function in the rat. PMID- 4215644 TI - Proceedings: Treatment of chronic proctitis with disodium cromoglycate. PMID- 4215645 TI - Proceedings: The influence of ethacrynic acid and aspirin on water and electrolyte secretion induced by prostaglandin E1 in the human jejunum. PMID- 4215646 TI - Proceedings: Serum complement components C3 and C4 in inflammatory bowel disease. PMID- 4215647 TI - Gel filtration of thyroxine - binding proteins of human serum. PMID- 4215648 TI - Thyroxine content in the thyroid gland of domestic animals. Part VII. Iodinated tyrosines and thyronines in the serum of she camel at various reproductive stages. PMID- 4215650 TI - Evidence in favour of the modification in vivo of RNA polymerase subunits during sporogenesis in Bacillus thuringiensis. PMID- 4215649 TI - The structure and metabolism of starch. PMID- 4215651 TI - Active transport of maltose in Escherichia coli K12. Involvement of a "periplasmic" maltose binding protein. PMID- 4215652 TI - A suppressor of nonsense mutations in Bacillus subtilis. PMID- 4215653 TI - Correlation between the level of vitamin-B12-dependent methionine synthetase and intracellular concentration of vitamin B12 in some bacteria. PMID- 4215654 TI - Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. PMID- 4215655 TI - Protein A from Staphylococcus aureus. The effect of iodination on the reactivity with immunoglobulin G. PMID- 4215656 TI - Purification and properties of alpha-D-mannosidase from Medicago sativa L. PMID- 4215657 TI - Inhibition by chloramphenicol of aminoazo dye carcinogenesis in rat liver: RNA synthesis in isolated liver nuclei. PMID- 4215658 TI - The relative biological effectiveness of cyclotron fast neutrons for early and late damage to the small intestine of the mouse. PMID- 4215659 TI - Histamine catabolism in guinea pigs, rats and mice. PMID- 4215660 TI - Differences in papaverine inhibition of prostaglandin-induced contraction of aortic strips from normal and spontaneously hypertensive rats (SHR). PMID- 4215661 TI - Determination of the LD01 and extrapolation of the LD001 for five methylcarbamate pesticides. PMID- 4215662 TI - [Detection and isolation of Pseudomonas aeruginosa in a mouse breeding colony]. PMID- 4215663 TI - [Management of the laboratory animal facility at the Medical Department of Kobe University]. PMID- 4215664 TI - [Management of laboratory monkeys]. PMID- 4215665 TI - Change in cell-to-dish contact of cultured mammalian cells induced by concanavalin A. PMID- 4215666 TI - Evidence for long-range electrostatic repulsion between HeLa cells. PMID- 4215667 TI - Vitamin B12 and the macromolecular composition of Euglena. I. Kinetic analysis of the cell cycle and chloroplast replication. PMID- 4215668 TI - Effect of bilateral intracerebral ablation on the gastric secretory response to insulin-induced hypoglycemia. PMID- 4215669 TI - Retention of noradrenaline-3H in brain and preferential extraction of labeled metabolites by glutaraldehyde fixation. PMID- 4215670 TI - Tremorogenic effect of thyrotropin releasing hormone in rats. PMID- 4215671 TI - Enhancement of cerebral noradrenaline turnover by thyrotropin-releasing hormone: evidence by fluorescence histochemistry. PMID- 4215672 TI - Reproductive incompatibility between similar genotype flies (Drosophila melanogaster) raised at two different temperatures. PMID- 4215673 TI - Effect of sulpiride on prolactin release by rat pituitaries in vitro. PMID- 4215674 TI - Studies on the influence of carboxyl-terminal amino acid residues on the activity and stability of human erythrocyte carbonic anhydrase B. PMID- 4215675 TI - Formation of D-alanyl-D-alanine and D-alanine from UDPMurNAc-L-Ala-D-isoGlu-L-Lys D-Ala-D-Ala by extracts of Staphylococcus aureus and Streptococcus faecalis. PMID- 4215676 TI - Isolation and characterization of allophycocyanin II from the thermophilic blue green alga Mastigocladus laminosus Cohn. PMID- 4215677 TI - Immunological studies on the sigma subunit of the RNA polymerase from vegetative and sporulating cells of Bacillus subtilis. PMID- 4215678 TI - Oxygen binding properties of Colus gracilis haemocyanin and its subunits. PMID- 4215679 TI - Carbonic anhydrase-aromatic sulfonamide complexes, a resonance Raman study. PMID- 4215681 TI - Computer-based auditory neurophysiology laboratory. PMID- 4215680 TI - Correlation between pyocin-sensitivity and 2-amino sugar composition of Pseudomonas aeruginosa. PMID- 4215682 TI - Induction of minute mutations in Drosophila by x-rays. PMID- 4215683 TI - Genetic (h-2) dependence of the duration of splenomegaly induced by Brucella abortus. PMID- 4215684 TI - Laboratory testing of some organic insecticides against Zyginidia quyumi (Ahmed) Typhlocybinae: (Cidadellidae) on maize. PMID- 4215686 TI - The status of transplantation of the pancreas and pancreatic tissues as a cure for diabetes. PMID- 4215685 TI - Protective antigens in bovine pasteurellosis. PMID- 4215687 TI - Influence of nifedipine on the effort tolerance test in angina pectoris. Comparison with placebo and trinitroglycerine. PMID- 4215688 TI - Nifedipine in angina pectoris. A multicentric clinical trial. PMID- 4215689 TI - Effect of anti-4-azoquinoline 1-oxide antibody on immunosuppression by 4 hydroxyaminoquinoline 1-oxide. PMID- 4215690 TI - Phenotypic properties of R factors of Pseudomonas aeruginosa: R factors readily transferable between Pseudomonas and the Enterobacteriaceae. PMID- 4215692 TI - The use of bacteriophages for differentiating plasmids of Pseudomonas aeruginosa. PMID- 4215691 TI - Phenotypic properties of R factors of Pseudomonas aeruginosa: R factors transferable only in Pseudomonas aeruginosa. PMID- 4215693 TI - Genetic analysis of amidase mutants of Pseudomonas aeruginosa. PMID- 4215694 TI - Genetic regulation and pattern formation: a study of the yellow locus in Drosophila melanogaster. PMID- 4215695 TI - Regulation of enzyme activities in Drosophila. I. The detection of regulatory loci by gene dosage responses. PMID- 4215696 TI - Regulation of enzyme activities in Drosophila. II. Characterization of enzyme responses in aneuploid flies. PMID- 4215697 TI - Rubella antibody titer and IgG concentration in an aging population. PMID- 4215698 TI - [Comparative survival in water of Enterococcus, Escherichia coli and Salmonella]. PMID- 4215699 TI - [Intal in the treatment of atopic extrinsic bronchial asthma. I. Effect on the ventilatory function]. PMID- 4215700 TI - [Intal in the treatment of atopic extrinsic bronchial asthma. II. Effect of intal on histamine concentration and blastic index in peripheral blood]. PMID- 4215701 TI - [Value of biological tests in the diagnosis of tuberculosis]. PMID- 4215702 TI - [Immunologic methods of detection of peroxidase in homogenates of BCG substrains. I. Description and evaluation of methods of immunological detection of peroxidase]. PMID- 4215703 TI - Supersensitivity to pentagastrin in diffuse oesophageal spasm. AB - A 38-year-old patient, complaining of dysphagia and substernal pain of nine months' duration, was found by manometric studies to have diffuse oesophageal spasm. As has similarly been reported for cholinergic agents in achalasia and in some cases of diffuse oesophageal spasm the oesophageal body responded in a hypersensitive fashion to subcutaneous and intravenous injections of pentagastrin. This effect was inhibited by the intravenous administration of atropine and completely abolished by nitroglycerine. When pentagastrin was subcutaneously injected before a barium examination a distortion of the oesophageal contour, described as curling or corkscrew oesophagus, regularly appeared. PMID- 4215704 TI - Some effects of a microcrystalline collagen preparation on blood. PMID- 4215706 TI - Professor Frantisek Patocka, septuagenarian. PMID- 4215705 TI - [Cyclopia: a rare case of congenital malformation]. PMID- 4215707 TI - Effect of rifampicin and free amino acids on replication of DNA in Lactobacillus acidophilus. PMID- 4215709 TI - Comparative studies of social behavior in Callicebus and Saimiri: behavior of male-female pairs. PMID- 4215708 TI - Spores of microorganisms. XXV. The effects of histone on the syntheses of macromolecules in germinating and outgrowing spores of Bacillus cereus. PMID- 4215710 TI - Male-male competition and infanticide among the langurs (Presbytis entellus) of Abu, Rajasthan. PMID- 4215712 TI - [Polyspecific associations of Cercopithecus species at M'passa Plateau (Gabon) (author's transl)]. PMID- 4215711 TI - Hematological development of the cebus monkey (Cebus albifrons and apella). PMID- 4215713 TI - Harassment of sexual behavior in the stumptail macaque, Macaca arctoides. PMID- 4215715 TI - Biological ensiling of sugarcane tops. VII. Isolation and characteristics of lactic acid bacteria. PMID- 4215714 TI - Regulation of biosynthesis of excessive metabolites. XVI. Origin of the terminal group of tetracyclines. PMID- 4215716 TI - Immunochemical studies on mannans of the genus Saccharomyces. Group of Saccharomyces sensu stricto species. PMID- 4215717 TI - [Studies on mycobacteriocin. II. Mycobacteriocin typing of human type tubercle bacilli (author's transl)]. PMID- 4215718 TI - [The primary structure of a monoclonal IgM-immunoglobulin (macroglobulin Gal.), I. The amino acid sequence of the L-chain of kappa-type, subgroup I (author's transl)]. PMID- 4215719 TI - The amino acid sequences of the alpha and beta polypeptide chains of adult hemoglobin of the capuchin monkey (Cebus apella). PMID- 4215720 TI - Studies on the primary structures of alpha and beta polypeptide chains of adult hemoglobin of the spider monkey (Ateles geoffroyi). PMID- 4215721 TI - Properties of a phenolase preparation from cell suspension cultures of parsley. PMID- 4215722 TI - [The primary structure of a crystalline, monoclonal immunoglobulin-L-chain of the kappa type, subgroup I (Bence-Jones protein Rei): a contribution to the elucidation of the three-dimensional structure of the immunoglobulins (author's transl)]. PMID- 4215723 TI - [On the inhibition of the proteinases from Pseudomonas aeruginosa by alpha2 macroglobulin (author's transl)]. PMID- 4215724 TI - Detection and isolation of a second acid stable proteinase inhibitor from human bronchial mucus. PMID- 4215726 TI - Alternative pathway for the activation of complement in human serum. Formation and composition of the complex with cobra venom factor that cleaves the third component of complement. PMID- 4215727 TI - The interaction of native and chemically modified yeast transketolase with a specific antibody. PMID- 4215725 TI - Thymus proteases: extraction, distribution, comparison to lymph node proteases and species variation. PMID- 4215728 TI - [Quantitative estimation of genetically determinated isoenzymes by immunotitration. Distribution patterns of aldolases A, B and C in extracts of human organs and tissues as well as in normal and pathological sera (author's transl)]. PMID- 4215729 TI - Glucose-6-phosphate 1-epimerase from bakers' yeast: purification, properties and possible biological function. PMID- 4215730 TI - Glycogen metabolism in isolated perfused rat liver. PMID- 4215731 TI - [Studies on a protease (elastase) from Pseudomonas aeruginosa, I: formation and purification of the protease (author's transl)]. PMID- 4215732 TI - The molecular weight of J chains of human IgM. PMID- 4215733 TI - Characterization of an acid-stable proteinase inhibitor in human cervical mucus. PMID- 4215734 TI - Steroidglucuronyltransferases, V. Formation and hydrolysis of oestrogen glucuronides by the liver, kidney and intestine of the pig. PMID- 4215735 TI - Biological, immunological and physical investigations on human chorionic gonadotropin. PMID- 4215736 TI - [Studies on a protease (elastase) from pseudomonas aeruginosa, II: Characterization of the enzyme (author's transl)]. PMID- 4215737 TI - The changing hospital economy. PMID- 4215738 TI - Drug effects on vision: strategies for study and selected results. PMID- 4215739 TI - Vitamin B12-like activity in leafy vegetables. PMID- 4215740 TI - The genetic control of T cell-meditated immunity. I. Characterization of a mouse strain whose low responsiveness is inherited as a recessive trait. PMID- 4215741 TI - The comparative serological response of the chicken, pheasant and quail to a soluble and a particulate antigen. PMID- 4215743 TI - Protection against Toxoplasma gondii in mice immunized with Toxoplasma cell fractions, RNA and synthetic polyribonucleotides. PMID- 4215742 TI - Quantification and distribution of chicken immunoglobulins IgA, IgM and IgG in serum and secretions. PMID- 4215744 TI - Surface immunoglobulin of a mouse T-cell lymphoma. PMID- 4215745 TI - Red cell Fc receptors and their participation in the passive haemagglutination mediated by non-precipitating antibodies. PMID- 4215747 TI - Formation of salicylic acid from naphthalene by microorganisms: Part I. Studies on isolation, characterization & growth of bacterial isolates utilizing naphthalene. PMID- 4215748 TI - Formation of salicylic acid from naphthalene by microorganisms: Part II. Factors affecting salicylic acid accumulation. PMID- 4215746 TI - Studies on the specificities of two IgM lambda cold agglutinins. PMID- 4215749 TI - Epizootiology of Kyasanur Forest Disease in wild monkeys of Shimoga district, Mysore State (1957-1964). PMID- 4215751 TI - Studies on foetomaternal haemorrhage (FMH). Part II. The role of placental pathology in foetomaternal haemorrhage. PMID- 4215752 TI - Improved cell yield from monkey kidneys by using versene and trypsin. PMID- 4215753 TI - Studies on the antibody response of a formalin inactivated Kyasanur Forest Disease Virus vaccine in langurs "Presbytis entellus". PMID- 4215750 TI - Studies on foetomaternal haemorrhage (FMH). Part I: Factors affecting foetomaternal haemorrhage. PMID- 4215754 TI - Significant bacteriuria in apparently healthy young adults. PMID- 4215755 TI - Mental development of children with severe protein calorie malnutrition in the past anbd present. PMID- 4215756 TI - Investigation of secretory immunoglobulins in saliva from germfree mice. AB - We investigated the effect of oral immunization on the serum and salivary immunoglobulin levels in axenic and conventional NIH mice. Specific antibacterial and antifungal antibodies were measured by passive hemagglutination, and differences in the immunoglobulin classes were measured by radial immunodiffusion. After an oral immunization regimen with either intact Escherichia coli or Candida albicans, a significant increase in specific antibody above the base-line reciprocal titer of 32 was observed in conventional mouse saliva. Saliva from axenic mice immunized with the formalized microorganisms yielded reciprocal antibody titers of 256, as compared with an absence of specific antibodies in control animals. Assay of the sera of both groups of immunized mice revealed no increase in antibody levels specific for E. coli lipopolysaccharide or Candidin. PMID- 4215758 TI - Some properties of precipitating antigens associated with infectious bursal disease virus. AB - Infection of the bursa of Fabricius and chicken embryo fibroblast cell cultures with avian infectious bursal disease virus resulted in production of a number of virus-induced antigens. The antigens were specific, forming three precipitin lines by immunodiffusion with antiserum (designated PA-1, -2, and -3). To separate immunoprecipitin from the remaining viral particles, two (PA-1 and PA-3) were partially purified by subjection to two cycles of diethylaminoethyl cellulose chromatography and filtration through a column of Sephadex G-150 gel. The precipitating antigen, PA-1, was found to migrate most slowly through the agar gel, remaining serologically active after treatment with heating (56 C for 1 h), trypsin, lipolytic solvents, deoxyribonuclease, and ribonuclease. Its density was 1.27 g/ml. Morphologically the antigen displayed a doughnut-shaped structure 8 to 12 nm in size. PA-3 migrated most rapidly through the agar gel. It was destroyed by treatment with heating and trypsin but not with lipolytic solvents, deoxyribonuclease, and ribonuclease. Density was about 1.25 g/ml. This suggests that the antigen is a part of viral structural components. PA-2 migrated through agar gel at a rate between that of PA-1 and PA-3. Because of its low concentration, PA-2 was not further characterized. PMID- 4215757 TI - Immunological study of typhoid: immunoglobulins, C3, antibodies, and leukocyte migration inhibition in patients with typhoid fever and TAB-vaccinated individuals. AB - The development of humoral and cell-mediated immune responses to Salmonella typhi antigens and immunoglobulin and C(3) levels were determined in patients suffering from typhoid fever, TAB-vaccinated individuals, and appropriate controls. In 45 patients with typhoid, a significant elevation of immunoglobulin M (IgM) level was noted from the first week of illness onwards. Eighteen TAB-vaccinated persons also showed a significant elevation of IgM levels. In typhoid sera, the anti-O and anti-H antibodies were mostly 2-mercaptoethanol (2-ME) sensitive. The rise of IgM level correlated well with the 2-ME-sensitive anti-O and anti-H antibodies seen in typhoid patients. The anti-O antibodies in the TAB-vaccinated group were almost entirely 2-ME sensitive, but both 2-ME-sensitive and -resistant anti-H antibodies were detected in the TAB group. A marked increas in C(3) level was also noted in patients with typhoid. The cell-mediated immunity (CMI), as measured by leukocyte migration inhibition tests, was demonstrable in 15 of 22 patients with typhoid. On the other hand, only 8 of the 20 normal subjects, 5 of the 16 fever control cases, and 6 of the 18 TAB-vaccinated individuals gave a positive CMI. The latter three groups were comparable with each other but were significantly different from the typhoid patients. It was concluded that TAB vaccination did not induce CMI even though it induced the development of antibodies, the latter being comparable with those of the patients with typhoid. The significance of these findings is discussed. PMID- 4215760 TI - Interaction of staphylococcal exfoliative toxin with concanavalin A. AB - Treatment of mouse embryo fibroblasts (MEF) grown in vitro with purified staphylococcal exfoliative toxin (ET) increased the concanavalin A (Con A) agglutinability of MEF 3.5-fold over control cells. Possible explanations for this phenomenon were investigated. ET lacked proteolytic activity on denatured casein. Con A, however, was found to interact directly with ET as evidenced by the formation of precipitation in an agar gel diffusion plate and in increased turbidity in solution. This interaction was inhibited by alpha-methyl-d glucopyranoside. The ability of Con A to precipitate with ET suggests that the toxin contains a carbohydrate component and that the carbohydrate associated with ET is branched rather than linear. An analysis of a purified preparation of ET indicated the presence of 9% carbohydrate and no lipid. PMID- 4215759 TI - Intracellular and extracellular degranulation of human polymorphonuclear azurophil and specific granules induced by immune complexes. AB - The nature of the phagocytic stimulus determines the degree of degranulation. Specifically, immune complexes induced more degranulation than did antigen or antibody alone. The release of constituents from the two granule classes represented independent phenomena. Relatively more of the specific granule proteins were released into the medium during phagocytosis, whereas more of the azurophil proteins were associated with the phagosomes. PMID- 4215761 TI - Immunological analysis of glycolipids and lipopolysaccharides derived from various mycoplasmas. AB - The lipids and lipopolysaccharides of five mycoplasmas were examined for complement-fixing activity to antimembrane rabbit sera. Total glycolipid fractions and the aqueous phenol fractions (lipopolysaccharides) from the membranes of Acholeplasma laidlawii, A. modicum, A. axanthum, and Mycoplasma neurolyticum exhibited significant antigenic activity. The glycolipids and phosphoglycolipids from Thermoplasma acidophilum were either anticomplementary or did not react due to their extreme hydrophobic nature. High activity was found using the lipopolysaccharide of T. acidophilum. The pure glycolipids and phosphoglycolipids of the Acholeplasma and Mycoplasma species also exhibited significant complement-fixing activity. Acylation of the sugar residues of these lipids reduced or negated complement-fixing activity. Double cross-reactions between the glycolipids of A. laidlawii and A. modicum appeared to be due to mono and diglucosyl diglycerides of identical structure. Specificity of glycolipid structure was noted by the absence of cross-reactions between A. laidlawii and M. neurolyticum, the glycolipids of which differ only in the nature of the glucose linkages. The existence of lipopolysaccharides in the membranes of mycoplasmas and their complement-fixing activity in the presence of antimembrane sera suggest their possible importance as specific antigenic determinants. PMID- 4215762 TI - Opsonin system of the group B streptococcus. AB - The opsonization by polymorphonuclear leukocytes of group B streptococcal serotypes associated with neonatal sepsis and delayed meningitis was studied. A specific BIa opsonizing antibody (not related to the antipolysaccharide typing antibody) was present in only 10% of the population tested. Serotype BIa was not opsonized in the absence of this specific antibody. BIa antibody specificity was demonstrated by macroagglutination and absorption with BIa streptococci and extracts, but not by gel diffusion. The binding of complement by the BIa opsonin increased the mean phagocytic activity by 60%; complement was manifested via the classic and/or alternate C3-related pathway, but seldom by both concurrently. Serotypes BIb, BIc, BII, and BIII were naturally and nonspecifically opsonized in 95% of the human and baboon sera or plasma tested. Although similar levels of opsonization were present in hyperimmune rabbit sera, heat inactivation and homologous bacterial absorption did not reduce the level of phagocytic activity in the rabbit, human, or primate groups studied. These immunological studies confirmed previous findings that serotype BIa presents a serious hazard for neonatal sepsis, with a nearly 100% mortality. Exclusive isolation of BIII in delayed meningitis suggests that ingestion and subsequent killing by polymorphonuclear leukocytes of type III may differ from the other serotypes. PMID- 4215766 TI - Conversion of serotype in Leptospira from hebdomadis to kremastos. AB - A mutant of Leptospira serotype hebdomadis, obtained by cultivating hebdomadis in the presence of the homologous immune serum, was serologically identical with kremastos. PMID- 4215767 TI - Surveillance and monitoring. PMID- 4215764 TI - Persistent infection of BSC-1 cells by defective measles virus derived from subacute sclerosing panencephalitis. AB - A line of cells (IP-3), persistently infected with defective measles virus, was developed from co-cultures of subacute sclerosing panencephalitis-derived brain cells with monkey kidney cells (BSC-1). The line, carried for more than 45 serial passages, produced neither infectious virus nor hemagglutinin. Cultures consistently displayed a cycling focal cytopathic pattern of infection characterized by formation of syncytia, necrosis, and plaques followed by healing. Fluorescent measles antigen was present in damaged areas only, especially in syncytia. The development of syncytia was suppressed by measles antibody. Syncytia were lysed by antibody plus rabbit complement. A variant noncytopathic subline (IP-3-Ca) was derived from the 16th passage. Infectious virus was not detected. Cells were minimally positive for hemadsorption. Fluorescent measles antigen was present in all cells. Co-cultures of IP-3-Ca cells with normal BSC-1 cells developed massive syncytia and extensive destruction. The IP-3-Ca cells multiplied in the presence of measles antibodies and were destroyed by antibodies plus complement. The possible relevance of these findings to the pathogenesis of subacute sclerosing panencephalitis is discussed. PMID- 4215763 TI - Modoc viral infections in the deer mouse Peromyscus maniculatus. AB - The pathogenesis of Modoc virus and its mechanism of transmission were investigated in Peromyscus maniculatus gambeli (deer mouse) as a model to understand the natural history of this virus. Animals were readily infected by the intranasal or subcutaneous route of inoculation. Virus could be detected by direct isolation techniques in many organs and body fluids during the first 7 to 9 days after intranasal inoculation. Increases in viral titers were detectable first in lungs and then the spleen, salivary-submaxillary glands, and lymph nodes. Viremias were low titered and ephemeral. Virus was recovered from urine and throat swabs 4 to 6 days and 4 to 7 days after inoculation, respectively. Serum dilution neutralization, hemagglutination inhibition, or complement fixation antibodies were detected in sera of some animals 13 days after infection and in all animals after 20 days. Antibodies persisted for the 168-day period of observation. Persistent viral infection was demonstrable by in vitro culturing of lungs or pooled lungs, salivary glands, and kidneys from 14 of 69 mice that were sacrificed from 1 to 6 months after intranasal inoculation. Attempts to demonstrate horizontal or vertical transmission of Modoc virus among mice were generally unsuccessful. Female deer mice infected with virus before mating passed maternal antibodies to their young. PMID- 4215769 TI - Application of a coincidence counting technique in a fixed geometry whole-body counter. PMID- 4215765 TI - Phase transition of gonococci in mammalian cell cultures. AB - Neisseria gonorrhoeae was cultivated in mammalian cell cultures in an effort to determine if this environment will elicit a T4 --> T1 transition. Of four avirulent (T4) isolates tested, only one, H4, yielded T1 colonies. This change was consistently obtained in HeLa, WI-38, and MK2 cells, even when the multiplicity of the gonococcal infection was less than 1 per culture. Growth of the gonococci took place primarily on the surface of the cells, as demonstrated by light and electron microscopy, but occasional bacteria were undoubtedly intracellular. T1 colonies were seen at 24 h and were the major population at 48 h. This shift was favored by the presence of viable cells, since smaller yields of T1 were obtained when the cells were irradiated or heat inactivated. It was also favored by low pH, since T1 recovery was reduced when the buffering capacity of the medium was increased. Although the results suggest that T1 gonococci derived from H4 have a selective advantage over T4 in cell cultures, this is not true of all T1 and T4 colony types. F62 T4, which does not undergo a T4 --> T1 shift, propagated as well as T1 in HeLa cell cultures. The change in colony type of strain H4 to T1 was accompanied by formation of pili and by gain in capacity for deoxyribonucleic acid-mediated transformation. It is concluded that gonococci can undergo T4 --> T1 phase transition in mammalian cell cultures, but this property is not retained by all strains. PMID- 4215768 TI - An improved radionuclide distribution profile from a fixed array whole-body counter using a mathematical analysis technique. PMID- 4215770 TI - Evaluation of the pituitary-thyroid axis by measuring the response of I-labelled thyroid hormones to TRH. PMID- 4215771 TI - The unit dose preparation of 63Zn-EDTA for use in nuclear medicine. PMID- 4215772 TI - Determination of the optimum window for whole body counting of 47Ca. PMID- 4215778 TI - Specific immunoassay for quantitative determination of human chymotrypsin. PMID- 4215773 TI - Recent advances in cytochemistry and ultrastructure of cytoplasmic inclusions in Ciliophora (Protozoa). PMID- 4215774 TI - Infectious DNA-protein complex from cells productively infected with simian adenovirus SA7. PMID- 4215776 TI - Pyroglutamyl-histidyl-prolineamide (TRH). A neurohormone which affects the release and synthesis of prolactin and thyrotropin. PMID- 4215777 TI - Human chorionic thyrotropin. Its relationship to thyroid stimulators from chorionic neoplasms and nonendocrine cancers. PMID- 4215775 TI - Heterogeneity of human luteinizing hormone. Behavior in radioimmunoassay and radio-ligand-receptor assay systems and evidence for the presence of alpha subunit in serum. PMID- 4215779 TI - [Surgical interventions in the course of chronic recurrent pancreatitis]. PMID- 4215780 TI - [A new method of cuff inflation for the prevention of tracheal complications during long term artificial respiration]. PMID- 4215781 TI - "B" and "C" isoenzymes of carboanhydrase in erythrocytes of mother, newborn infant and umbilical cord. Immunofluorescence study. PMID- 4215782 TI - Current concepts of patient motivation toward long term oral hygiene: a literature review. PMID- 4215784 TI - The effect of incubation temperature on the recovery of spores of Bacillus subtilis 8057. PMID- 4215785 TI - Rapid screening for the isolation of mutants of Aspergillus nidulans with increased penicillin yields. PMID- 4215783 TI - Synthesis of 4'-deoxykanamycin and its resistance to kanamycin phosphotransferase II. PMID- 4215786 TI - The immunopurification of tetanus toxoid. PMID- 4215787 TI - Intra- and interspecies variability of vertebrate high-pressure neurological syndrome. PMID- 4215789 TI - Genetic basis of nutritional requirements in Lactobacillus casei. AB - In a study of the genetic basis of multiple nutritional requirements in Lactobacillus casei, systematic attempts were made to isolate mutants that can grow in the absence of a specific nutrient required by the parental organism. Such mutants have successfully been isolated with respect to seven of twelve amino acids (aspartic acid, leucine, isoleucine, lysine, methionine, serine, and threonine) and three of four vitamins (pantothenic acid, nicotinic acid, and pyridoxal) tested, after extensive screenings employing various mutagens. Mutants that can grow without tryptophan were not isolated, but those that can grow on anthranilate or indole as well as on tryptophan were obtained at a frequency expected for single-step mutations. Activity of tryptophan synthetase was demonstrated in extracts of these anthranilate-utilizing mutants, but not in the parental strain. These results suggest that the multiple nutritional requirements of L. casei are often, if not always, due to one or a few small lesions such as base substitution mutations rather than large deletions affecting the genes involved in each biosynthetic pathway. The data would also imply that many of the biosynthetic pathways that are not fully functional in L. casei were active at one time and became nonfunctional during evolution of the present species. PMID- 4215788 TI - [Problems of radiation protection in fast-neutron radio therapy]. PMID- 4215790 TI - Active transport of D-alanine and related amino acids by whole cells of Bacillus subtilis. AB - Whole cells of Bacillus subtilis transported d-alanine and l-alanine by two different systems. The high-affinity system (K(m) of 1 muM and V(max) of 0.6 to 0.8 nmol/min per mg of protein) was specific for the two stereoisomers of alanine. The low-affinity system (K(m) of 10 muM for l-alanine and 20 muM for d alanine and glycine) had a V(max) of 5 to 12 nmol/min per mg of protein. This system transported glycine, d-cycloserine, and d-serine, in addition to d- and l alanine. Azide inhibited the uptake of these amino acids and caused the efflux of d-alanine from preloaded cells. These data suggest that transport of these amino acids is energized by the electron transport chain. PMID- 4215791 TI - Comparative studies on induction of sporulation and synthesis of inducible enzymes in Bacillus subtilis. AB - An attempt was made to determine whether sporulation and inducible enzyme synthesis in Bacillus subtilis are controlled by the same mechanism of catabolite repression. By the use of a thymine-requiring strain, it has been shown that, whereas sporulation remained repressed unless chromosome replication proceeded to completion, the induction of the enzymes histidase, sucrase, and alpha glucosidase proceeded quite normally in the absence of continued deoxyribonucleic acid synthesis. It is concluded that the mechanism for overcoming the repression of sporulation differs qualitatively from that involved in overcoming the repression of inducible enzyme synthesis. Attempts to isolate pleiotropic mutants that would provide additional support for this contention were unsuccessful. A pleiotropic mutant deficient in phosphoenolpyruvate-dependent phosphotransferase activity sporulated quite well, whereas a mutant presumed deficient in glutamate synthetase sporulated poorly under all conditions. PMID- 4215792 TI - Mis-regulation of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase does not account for growth inhibition by phenylalanine in Agmenellum quadruplicatum. AB - The growth of the blue-green bacterium, Agmenellum quadruplicatum, is inhibited in the presence of l-phenylalanine. This species has a single, constitutively synthesized 3-deoxy-d-arabino-heptulosonate 7-phosphate (DAHP) synthetase. l Phenylalanine inhibits DAHP synthetase non-competitively with respect to both substrate reactants. Other aromatic amino acids do not inhibit the activity of DAHP synthetase. A common expectation for branch-point enzymes such as DAHP synthetase is a balanced pattern of feedback control by all of the ultimate end products. It seemed likely that growth inhibition might equate with defective regulation within the branched aromatic pathway. Accordingly, the possibility was examined that mis-regulation of DAHP synthetase by l-phenylalanine in wild-type cells causes starvation for precursors of the other aromatic end products. However, the molecular basis for growth inhibition cannot be attributed to l phenylalanine inhibition of DAHP synthetase for the following reasons: (i) DAHP synthetase enzymes from l-phenylalanine-resistant mutants are more, rather than less, sensitive to feedback inhibition by l-phenylalanine. (ii) Shikimate not only fails to antagonize inhibition, but is itself inhibitory. (iii) Neither the sensitivity nor the completeness of l-phenylalanine inhibition of the wild-type enzyme in vitro appears sufficient to account for the potent inhibition of growth in vivo by l-phenylalanine. The dominating effect of l-phenylalanine in the control of DAHP synthetase appears to reflect a mechanism that prevents rather than causes growth inhibition by l-phenylalanine. The alteration of the control of DAHP synthetase in mutants selected for resistance to growth inhibition by l phenylalanine did indicate that the cause for this metabolite vulnerability can be localized within the aromatic amino acid pathway. Apparently, an aromatic intermediate (between shikimate and the end products) accumulates in the presence of l-phenylalanine, causing toxicity by some unknown mechanism. It is concluded that phenylpyruvate, potentially formed by transamination of l-phenylalanine, is an unlikely cause of growth inhibition. Although several significant questions remain unanswered, our results suggest that single-effector control of DAHP synthetase, the first regulatory enzyme activity of a branched pathway, may be more appropriate than it would seem a priori. PMID- 4215793 TI - Transformation of Bacillus subtilis in alpha-amylase productivity by deoxyribonucleic acid from B. subtilis var. amylosacchariticus. AB - Deoxyribonucleic acid (DNA) of Bacillus subtilis var. amylosacchariticus showed almost the same ability as B. subtilis Marburg to induce transfer of several genetic markers in DNA-mediated transformation. DNA-DNA hybridization data also showed an intimate relationship between the two strains. Genetic elements involved in the production of extracellular alpha-amylase (EC 3.2.1.1.) in B. subtilis var. amylosacchariticus were studied by using DNA-mediated transformation. Two Marburg derivatives, NA20(amyR2) and NA20-22(amyR1), produced about 50 and 10 U of alpha-amylase per mg of cells, respectively, whereas B. subtilis var. amylosacchariticus produced as much as 150 U of the enzyme per mg of cells. When B. subtilis var. amylosacchariticus was crossed with strain NA20 22 as recipient, transformants that acquired high alpha-amylase productivity (about 50 U/mg of cells) were obtained. Genetic analysis revealed that a regulator gene (amyR) for alpha-amylase synthesis was found in B. subtilis var. amylosacchariticus, as in the case of B. natto 1212 (amyR2) and B. subtilis Marburg (amyR1). The allele was designated amyR3; it is phenotypically indistinguishable from amyR2, but is readily distinguishable from amyR1. The presence of amyR3 was not sufficient for an organism to render production of an exceptional amount of alpha-amylase. Extra-high alpha-amylase producers could be obtained by crossing B. subtilis var. amylosacchariticus as donor with strain NA20 as recipient. The transformants produced the same or even greater amounts of the enzyme than the donor strain. Results suggest the presence of another gene that is involved in the production of the exceptional amount of alpha-amylase. PMID- 4215795 TI - Existence of a free form of a specific membrane lipoprotein in gram-negative bacteria. AB - The existence of a free form of a specific lipoprotein of molecular weight 7,200 was examined in the envelopes of several gram-negative bacteria. When the envelope proteins were analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis, distinct peaks were observed in Salmonella typhimurium, Serratia marcescens, and Pseudomonas aeruginosa at the same position as the free form of the lipoprotein of Escherichia coli. However, the peak was not observed in Proteus mirabilis. The protein at the peak in S. typhimurium was shown to contain little or no histidine as expected from the amino acid composition of the lipoprotein. Furthermore, antiserum against the highly purified lipoprotein from E. coli was shown to react with the proteins from S. typhimurium and S. marcescens and to form the specific immunoprecipitates. In contrast, the protein from P. aeruginosa did not react with the antiserum at all. Thus, it is concluded that S. typhimurium and S. marcescens have the free form of the lipoprotein in their envelopes as does E. coli. P. aeruginosa contains a protein of the same size as the lipoprotein, but it is not certain whether the protein is the same structural protein as the lipoprotein from E. coli. P. mirabilis may not have any free form of the lipoprotein, may have it in a very small amount, or may have a lipoprotein of different molecular weight serving the same function. PMID- 4215794 TI - Genetic and biophysical study of R plasmids conferring sulfonamide resistance in Shigella strains isolated in 1952 and 1956. AB - The conjugative plasmids determining sulfonamide resistance in five Shigella strains, each isolated from a different patient, have been characterized. One S. flexneri 2a strain, isolated in 1952, harbored an fi(+) plasmid of molecular weight 53 x 10(6), which specified synthesis of F-like pili and bore determinants for sulfonamide resistance (Su) and bacteriocinogeny (Col). This plasmid was compatible with plasmids of groups F(I), F(II), I(alpha), and P. A second S. flexneri 2a strain isolated in 1952 harbored an fi(-) plasmid of molecular weight 59 x 10(6), bearing the Su determinant and compatible with all plasmids tested. This strain also harbored an fi(+) group-F(II) plasmid of molecular weight 42 x 10(6), which bore the Col determinant and specified synthesis of F-like pili. Three S. dysenteriae 2 strains isolated in 1956 carried apparently identical fi( ) plasmids of molecular weight 58 x 10(6), which bore the Su determinant, could form transconjugants in Pseudomonas but not in Proteus, and were incompatible with the P-group plasmid RP4. PMID- 4215796 TI - Relationship between lysogeny, spontaneous induction, and transformation efficiencies in Bacillus subtilis. AB - The low transformation efficiency of Bacillus subtilis 168 lysogenic for phages o105 or SPO2 is shown to result from the induction of lytic phage replication in competent cells. Lysogenic competent cells have a higher rate of spontaneous prophage induction than noncompetent cells. Mutants of o105 and SPO2 which form lysogens resistant to spontaneous induction were isolated, and these lysogens exhibited higher transformation levels than those formed by wild-type phage. These results suggest that the physiological state of competence in B. subtilis promotes prophage derepression leading to cell death and the loss of potential transformants. PMID- 4215797 TI - Natural messenger ribonucleic acid-directed cell-free protein-synthesizing system of Bacillus subtilis. AB - A very active in vitro protein-synthesizing system has been developed from Bacillus subtilis. High activity in the extracts is dependent upon precautions taken to reduce proteolytic activity. Endogenous, exogenous natural and synthetic messenger ribonucleic acids (RNAs) are translated by the system. The activity of the B. subtilis system has been compared to that of the Escherichia coli system. With either SPO1 RNA or polyuridylic acid, the activities of the two systems were very similar. Electrophoresis of the products synthesized in vitro by the two systems primed with SPO1 RNA yields similar radioactive profiles. The major bands of radioactivity correspond to proteins of molecular weight between 15,000 and 40,000. PMID- 4215798 TI - Requirement of deoxyribonucleic acid synthesis for microcycle sporulation in Bacillus megaterium. AB - Bacillus megaterium cells have been examined during outgrowth for their macromolecular content, ability to undergo microcycle sporulation, the time of their growth division, the time of deoxyribonucleic acid (DNA) replication initiation, and their ability to synthesize DNA after transfer to sporulation medium. The increase in total DNA content of the cells increased discontinuously beginning at 90 min. Thymidine incorporation became insensitive to chloramphenicol between 90 and 105 min of outgrowth. At 90 min the cells acquired the ability to undergo microcycle sporulation and the degree of sporulation depended on the time spent in outgrowth, with maximal sporulation occurring at 180 min. During outgrowth, cells underwent one synchronous growth division beginning at 225 min and ending at 270 min. Outgrowing cells were not able to continue DNA synthesis after transfer to sporulation medium. The data suggest that DNA replication starts before cells are able to undergo microcycle sporulation; however, the initiation of replication may not be the only requirement for microcycle sporulation. PMID- 4215799 TI - Developmental modulation of deoxyribonucleic acid-binding proteins of Bacillus subtilis during sporulation stages. AB - The isolation of deoxyribonucleic acid (DNA)-binding proteins from various stages of growth and sporulation of Bacillus subtilis is described. After adsorption and elution from phosphocellulose, the proteins were fractionated according to their ability to adsorb to denatured calf thymus DNA-cellulose or native B. subtilis DNA-cellulose. The proteins were analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis, and purification was monitored by a nitrocellulose filter binding assay. Approximately 1% of the proteins in the crude extract adsorbed to denatured calf thymus DNA-cellulose and 0.1% adsorbed to native B. subtilis DNA-cellulose. Each class of proteins varied qualitatively and quantitatively as sporulation proceeded. Several proteins from the exponential phase of growth that bound to denatured DNA were lost by T(0), whereas at T(5) new polypeptides appeared. Fewer changes in the profile of proteins with affinity for native DNA were observed between exponential phase and T(0); however, the dominant species in these eluates were clearly different. PMID- 4215800 TI - Effect of pH on the proportions of polar lipids, in chemostat cultures of Bacillus subtilis. AB - Significant changes in the relative proportions of the individual polar lipids of two strains of Bacillus subtilis were observed when the pH of their chemostat cultures was varied. In phosphate- and magnesium-limited cultures of B. subtilis var. niger NCIB 8058. lysylphosphatidylglycerol was present in higher proportions at low pH (5.1) than at neutral pH. With magnesium-limited cultures of this strain harvested at pH 8.0, lysylphosphatidylglycerol and phosphatidylethanolamine were not detected. Phosphate-limited cultures of B. subtilis NCIB 3610 contained no phosphatidylethanolamine or lysylphosphatidylglycerol at neutral pH, but at low pH (5.1) both these lipids were present in substantial proportions. The proportions of phosphatidylglycerol in actively dividing cells of chemostat cultures of bacilli were always greater than those of lysylphosphatidylglycerol. The reverse is commonly found in batch cultures of bacilli and staphylococci harvested at low pH. Changes in the proportions of the other polar lipids present in these bacilli (diphosphatidylglycerol and diglucosyl diacylglycerol) with pH were also noted. Certain cultures of both strains of B. subtilis contained small proportions of a peptidolipid. PMID- 4215801 TI - Structure and immunological properties of D-arabino-D-galactans isolated from cell walls of Mycobacterium species. PMID- 4215802 TI - Immobilized enzymes. I. Immobilization of carboxypeptidase CN, a preparation from Citrus natsudaidai Hayata. PMID- 4215803 TI - Cell-surface changes of phosphate-deficient Escherichia coli as characterized by increased stability and decreased concanavalin A-agglutinability of the spheroplast. PMID- 4215804 TI - The role of tyrosine residue of bacterial liquefying alpha-amylase in the enzymatic hydrolysis of linear substrates as studied by chemical modification with acetic anhydride. PMID- 4215805 TI - Studies on ribosomal ribonucleic acid from yeast. II. Specific complex of yeast ribosomal RNA. PMID- 4215806 TI - The number of subsites in the active site of saccharifying alpha-amylase from Bacillus subtilis. PMID- 4215807 TI - Gel chromatography and gel electrophoresis of histones in denaturing solvents. Limited dependence on molecular weight. PMID- 4215808 TI - Studies on cellulase produced by the phytopathogens. Purification and enzymatic properties of cellulase of Fusarium moniliforme. PMID- 4215809 TI - Partial purification and some properties of pyruvate-aspartic semialdehyde condensing enzyme from sporulating Bacillus subtilis. PMID- 4215810 TI - Studies on cathepsins of rat liver lysosomes. I. Purification and multiple forms. PMID- 4215811 TI - Difference in the molecular size of hepatic cytosol glycogen synthetase in tadpole and adult frog, Rana catesbeiana. PMID- 4215812 TI - Affinity chromatography of neutral and alkaline proteases from Bacillus subtilis and of thermolysin. PMID- 4215814 TI - Characterization of vitamin B12-binding proteins isolated from human milk and saliva by affinity chromatography. PMID- 4215813 TI - Rat liver alkaline phosphatase. Purification and properties. PMID- 4215815 TI - Widespread distribution of lysozyme g in egg white of birds. PMID- 4215816 TI - Relationships among enzymes of the beta-ketoadipate pathway. IV. Muconolactone isomerase from Acinetobacter calcoaceticus and Pseudomonas putida. PMID- 4215817 TI - Comparative experience with endocardial and epicardial pacemakers. PMID- 4215818 TI - The regeneration of cilia in partially deciliated Tetrahymena. AB - Partial deciliation of Tetrahymena resulted in cells losing 75% of their cilia, with the balance being paralyzed. The paralyzed cilia are resorbed in the first 20 min after partial deciliation, and regeneration of cilia begins before resorption is completed. Inhibition of protein synthesis with cycloheximide does not inhibit ciliary resorption or regeneration, whereas vinblastine sulfate inhibits regeneration but not resorption. Inhibition of regeneration occurs in completely deciliated cells when they are treated with cyclohexmimide or vinblastine sulfate. It is concluded that the resorbing cilia contribute materials which allow regeneration to occur in the absence of protein synthesis. The volume of cilia regenerated in the presence of cycloheximide in partially deciliated cells is greater than the ciliary volume which is resorbed. This suggests the Tetrahymena cells have a pool of ciliary precursors. This pool does not contribute materials for regeneration in completely deciliated cells which are treated with cycloheximide. It is concluded that resorbing cilia in partially deciliated cells contribute materials which potentiate assembly of cilia from the pool of precursors. PMID- 4215819 TI - Intramembrane particle aggregation in erythrocyte ghosts. I. The effects of protein removal. AB - We have used freeze-etching and SDS-polyacrylamide gel electrophoresis to study the conditions under which the intramembrane particles of the human erythrocyte ghost may be aggregated. The fibrous membrane protein, spectrin, can be almost entirely removed from erythrocyte ghosts with little or no change in the distribution of the particles. However, after spectrin depletion, particle aggregation in the plane of the membrane may be induced by conditions which cause little aggregation in freshly prepared ghosts. This suggests that the spectrin molecules form a molecular meshwork which limits the translational mobility of the erythrocyte membrane particles. PMID- 4215820 TI - Properties of flagellar "rigor waves" formed by abrupt removal of adenosine triphosphate from actively swimming sea urchin sperm. AB - Sea urchin sperm were demembranated and reactivated with a solution containing 0.04% Triton X-100 and 0.03 mM ATP. The ATP concentration was then lowered abruptly by diluting the sperm suspension 50-fold into reactivating solution containing no ATP. The flagella of the sperm in the diluted suspension were not motile, but they were bent into a variety of stationary rigor wave forms closely resembling the wave forms occurring at different stages of the flagellar bending cycle during normal movement. The form of these rigor waves was unchanged upon storage for several hours in the presence of dithiothreitol and EDTA. Addition of 1 microM ATP induced slow relaxation of the waves, with most of the sperm becoming partially straightened over a period of about 30 min; somewhat higher concentrations gave a more rapid and complete relaxation. Concentrations of ATP above 10 microM induced resumption of normal beating movements. Addition of ITP, GTP, or GDP (up to 1 mM) produced no relaxation of the rigor waves. Digestion with trypsin to an extent sufficient to disrupt the radial spokes and the nexin links caused no change in the rigor wave forms, suggesting that these wave forms could be maintained by the dynein cross-bridges between the outer doublet tubules of the flagellar axoneme. Study of the effects of viscous shear on the rigor wave axonemes has shown that they are resistant to distortion by bending, although they can be twisted relatively easily. PMID- 4215821 TI - Myonemal contraction of Spirostomum. I. Kinetics of contraction and relaxation. PMID- 4215822 TI - Lipid chromatographic determination of nitroglycerin products in waste waters. PMID- 4215823 TI - The extraction and recovery of chlorinated insectides and polychlorinated biphenyls from water using porous polyurethane foams. PMID- 4215826 TI - Oral thyrotropin-releasing hormone (TRH) in depressive illness. PMID- 4215825 TI - The role of collagen quaternary structure in the platelet: collagen interaction. AB - WE HAVE INVESTIGATED WHETHER COLLAGEN QUETERNARY STRUCTURE IS REQUIRED FOR THE PLATELET: collagen interaction. Quaternary structure refers to the assembly of collagen monomers (tropocollagen) into polymers (native-type fibrils). Purified monomeric collagen was prepared from acetic acid extracts of fetal calfskin. Polymeric collagen was prepared by dispersion of bovine Achilles tendon collagen and by incubation of monomeric collagen at 37 degrees C and pH 7.4. The state of polymerization was confirmed by electron microscopy. Release of platelet serotonin in the absence of platelet aggregation was used to determine the effectiveness of the platelet: collagen interaction. All forms of collagen produced serotonin release only after a lag period, but polymeric collagen gave a shorter lag period than did monomeric collagen. Monomeric collagen was also quanidinated selectively to convert collagen lysine groups to homoarginine, while leaving the arrangement of polar groups intact. Guanidination of monomeric collagen increased the rate of polymerization and reduced the lag time in serotonin release. Glucosamine (17 mM) retarded polymerization and inhibited the release of platelet serotonin by monomeric collagen but had little effect on release produced by thrombin or polymeric collagen. At the same concentration, glucosamine did not reduce the sensitivity of platelets to stimulation by collagen or block the platelet: collagen interaction. The only effect of glucosamine was on the collagen: collagen interaction. Galactosamine had a similar effect, but glucose, galactose, and N-acetylglycosamine had no effect. We conclude from this data that collagen monomers cannot effectively interact with platelets and that, therefore, collagen quaternary structure has a role in the recognition of collagen by platelets. PMID- 4215824 TI - Biologic variation of human serum immunoglobulin concentrations: sex-age specific effects. PMID- 4215827 TI - Fiber projections from trigeminal nucleus caudalis in primate (squirrel monkey and baboon). PMID- 4215828 TI - Efferent cortico-cortical fiber connections of area 18 in the squirrel monkey (Saimiri). PMID- 4215829 TI - Ordered arrangement of orientation columns in monkeys lacking visual experience. PMID- 4215830 TI - A third species of the owl monkey (Aotus). PMID- 4215831 TI - Salmonella O antigen-coated red blood cells as a stable reagent for passive hemagglutination tests. PMID- 4215832 TI - Detection of human IgA subclasses and allotypes by polymer-induced preciptation in agarose gel. PMID- 4215833 TI - A modified 51Cr release assay for cytotoxic lymphocytes. PMID- 4215835 TI - In vivo abrogation of serum C3 and C5 by administration of cobra venom factor and heterologous anti-C3. PMID- 4215834 TI - The cryopreservation of sheep erythrocyte intermediates EA nad EAC4 in complement assays. PMID- 4215836 TI - Paraformaldehyde fixation in immunofluorescence and immunoelectron microscopy. Preservation of tissue and cell surface membrane antigens. PMID- 4215837 TI - Effects of dextrans on immunoprecipitation in agar and in low-temperature-gelling agarose gels. PMID- 4215838 TI - Management of dysphagia. PMID- 4215839 TI - [Serological classification of staphylococci-comparison between Oeding's method and Tachikawa's method]. PMID- 4215840 TI - [Significance of percutaneous cholangiography in surgical treatment of long term biliary carriers of typhoid and paratyphoid]. PMID- 4215841 TI - [Localized epidemic of whooping cough; epidemiological survey and results of clinical examinations]. PMID- 4215842 TI - [In memory of late Prof. Shinichi Matsuda]. PMID- 4215844 TI - [Case of bacteremia caused by Salmonella enteritidis]. PMID- 4215845 TI - [Record of typhoid (B-2 type) outbreaks occurring simultaneously in Narumi district of Nagoya City and Toyota City, Aichi Prefecture, during September October, 1972]. PMID- 4215843 TI - [Effect of beta-lactam antibiotic inactivating substance produced by gram negative rods on the treatment of mixed infection]. PMID- 4215846 TI - [Epidemiological survey on typhoid outbreaks in Matsuyama City and Iyo City, Ehime Prefecture in October, 1972]. PMID- 4215848 TI - [Quantitative culture of bacteria by dip-slide system--especially a simple quantitative culture of urinary bacteria]. PMID- 4215847 TI - [Report on typhoid-paratyphoid control--patient distribution in 1972 and results of typing of the isolates]. PMID- 4215849 TI - [Bacteriological statistics of hospital patients]. PMID- 4215850 TI - [Neonatal meningitis caused by Flavobacterium meningosepticum: a case report]. PMID- 4215851 TI - [Meningitis caused by Listeria monocytogenes type 4d; a case report]. PMID- 4215852 TI - [Surgical treatment of empyema caused by Pseudomonas aeruginosa]. PMID- 4215853 TI - [Symposium on hyperlipidemia--epidemiological, clinical and experimental studies. Pathogenesis of hyperlipemia in biliary obstruction (author's transl)]. PMID- 4215854 TI - [Gold therapy in bronchial asthma with special emphasis upon blood level of gold and its teratogenicity (author's transl)]. PMID- 4215855 TI - [A case of macroglobulinemia masquerading as orbital pseudolymphoma (author's transl)]. PMID- 4215856 TI - [Anatomy of the masticatory muscle]. PMID- 4215857 TI - Hospital-acquired infections. How they occur and what can be done to prevent them. PMID- 4215858 TI - A comparative study: health care delivery in New Jersey county, state, Federal, and private mental hospitals. PMID- 4215859 TI - Electron microscopy of the trichocyst in Urostyla cristata, a hypotrichous ciliate. PMID- 4215860 TI - Observations on the effect of human chorionic gonadotrophin on the antler cycle of fallow deer. PMID- 4215861 TI - Melanocyte developmental genetics: biophasic control of dopa oxidase activity by the E locus of the fowl. PMID- 4215862 TI - Microbial synthesis of folate polyglutamates from labelled precursors. PMID- 4215863 TI - Observations on methionine transport in Pseudomonas fluorescens UK1. PMID- 4215864 TI - The biosynthesis of biotin in an auxotrophic strain of Humicola. PMID- 4215865 TI - Some properties of a bacterial protease with a specific effect on the protein in tobacco rattle virus particles. PMID- 4215866 TI - The selective isolation of nocardia from soil using antibiotics. PMID- 4215867 TI - Pseudomonas aeruginosa mutants defective in heptane oxidation. PMID- 4215868 TI - Fungal growth rate and the formation of ethylene in soil. PMID- 4215869 TI - Three previously undescribed viruses from the honey bee. PMID- 4215870 TI - Distribution of acetylcholine, choline, choline acetyltransferase and acetylcholinesterase in regions and single identified axons of the lobster nervous system. PMID- 4215871 TI - Axonal growth and organization of the mamillary nuclei of the newborn mouse in culture. PMID- 4215872 TI - Responses to tonal stimuli of single auditory nerve fibers and their relationship to basilar membrane motion in the squirrel monkey. PMID- 4215873 TI - Studies on the metabolic interrelationship between biotin and folic acid in rats. PMID- 4215874 TI - [Neurophysiological mechanism of taste sensation]. PMID- 4215875 TI - Immunopathological studies on cryoimmunisation of the rabbit male accessory glands. PMID- 4215876 TI - Dipetalonema barbascalensis sp. n. (Nematoda:Filarioidea) from the owl monkey, Aotus trivirgatus, with a consideration of the status of Parlitomosa zakii Nagaty, 1935. PMID- 4215877 TI - Isolation of Trypanosoma cruzi from blood. PMID- 4215878 TI - Relationship between periodontal injury, selective cell repopulation and ankylosis. PMID- 4215879 TI - Further studies on the role of prostaglandin in fever. AB - 1. Experiments were carried out in unanaesthetized cats to find out if a prostaglandin is the mediator (a) for the long lasting fever which often follows injections of phsyiological salt solutions into the cerebral ventricles or into the cisterna magna, as well as their perfusions through the cerebral ventricles, and (b) for the sodium fever which occurs during a perfusion of the cerebral ventricles with calcium-free artificial c.s.f. A fever mediated by prostaglandin should be accompanied by an increase of prostaglandin activity in cisternal c.s.f., and be abolished or prevented by antipyretics like paracetamol or indomethacin which inhibit prostaglandin synthesis. Both criteria were applied.2. The fever which follows injections or perfusions of physiological salt solutions appears to be mediated by a prostaglandin of the E series, probably E(2) (PGE(2)) because it was accompanied by increased prostaglandin E-like activity in the c.s.f. and abolished by paracetamol and indomethacin. During the first few days after pre-treatment of the cats with intramuscular chloramphenicol the injections were rarely followed by fever.3. The fever which occurs during a perfusion with calcium-free artificial c.s.f. appears not to be mediated by prostaglandin, because it was not associated with increased prostaglandin activity in the cisternal effluent, and not prevented by paracetamol or indomethacin, although these antipyretics usually attenuated the fever.4. A perfusion of the cerebral ventricles with artificial c.s.f. containing calcium in an abnormally high concentration (6.25 mM) brought down fever produced by PGE(1), or PGE(2), or bacterial pyrogen. PMID- 4215881 TI - [Control of cellular division by vitamin B 12 and folates]. PMID- 4215880 TI - Role of cations, anions and carbonic anhydrase in fluid transport across rabbit corneal endothelium. AB - 1. A small electrical potential difference (541 +/- 48 muV, aqueous side negative) across rabbit corneal endothelium has been recently found. Its dependence on ambient [Na(+)], [K(+)], [H(+)] and metabolic and specific inhibitors was examined.2. Changes in concentration of the ions above either were known or were presently shown to affect the rate of fluid transport across this preparation (normal value: 5.2 +/- 0.4 mul./hr.cm(2)). Ionic concentration changes were also found here to influence potential difference in the same way as fluid transport. In the cases tested, the effects on both fluid transport and potential difference were reversible.3. Fluid transport and potential difference were both decreased or abolished in absence of Na(+), K(+) and HCO(3) (-), and when [H(+)] was decreased. Fluid transport and potential difference were saturable functions of [HCO(3) (-)] and half-saturation occurred in both cases at about 13 mM-HCO(3) (-). The potential difference was also a saturable function of [Na(+)] (half-saturation around 15 mM). There was a pH optimum for potential difference in the range 7.4-7.6. Lower pH values decreases the potential difference and the fluid transport, and a small (-100 muV) reversed potential was observed in the range of 5.3-5.5.4. Total replacement of Cl(-) by HCO(3) (-) or SO(4) (2-) produced no impairment on either fluid transport or potential difference.5. Carbonic anhydrase inhibitors (ethoxyzolamide 10(-5) or 10(-4)M and benzolamide 10(-3)M) produced a 40-60% decrease in the rate of fluid pumping. In contrast, ethoxyzolamide 10(-4)M or acetazolamide 10(-3)M did not produce any change in the potential difference. NaCN and Na iodoacetate (both 2 mM) eliminated the potential difference in 1-1.5 hr while in controls it lasted for 5 6 hr.6. Ouabain (10(-5)M) abolished the potential difference in less than 10 sec when added to the aqueous side, which suggests the existence of an electrogenic pump. This extremely fast time transient can be accounted for by the accessibility and simple geometry of the present monocellular layer. Ouabain abolished also the reversed potential difference observed at low pH.7. The data are interpreted in terms of a scheme similar to that advanced for other epithelia and in which (a) H(+) would be pumped into the intercellular spaces, while Na(+) and CO(2) would enter into the cells, and (b) Na(+) would be subsequently pumped into the aqueous humour, producing as a result the fluid movement observed. The actual origin of the potential difference is further discussed in terms of two contrasting possibilities: (i) one or more electrogenic pumps, and (ii) a neutral pump which would create a diffusion potential across ;leaky' intercellular junctions. PMID- 4215882 TI - [Proceedings: The modern radiotherapy department and its environment. Introduction]. PMID- 4215883 TI - Effect of oral contraceptives on body water and electrolytes. PMID- 4215884 TI - Freeze-substitution: a method for the rapid arrest and chemical fixation of spermatozoa. PMID- 4215885 TI - Thermoelectric freeze-drying. PMID- 4215886 TI - Third National Cancer Survey--an overview of available information. PMID- 4215887 TI - An antigen-binding cell tumor: heterophile cold hemagglutinin as a membrane-bound receptor on a mouse lymphoma. PMID- 4215888 TI - The arm/head ratio in the assessment of protein-calorie malnutrition in Baghdad. PMID- 4215890 TI - Fungal nephritis in a grey-headed albatross. PMID- 4215889 TI - The significance of perineal pathogens in women. PMID- 4215891 TI - Case reports of ossifying fibromata in the striped mullet. PMID- 4215892 TI - Opercular cyst formation in trout infected with Myxosoma cerebralis. PMID- 4215894 TI - Hematozoa of the Anatidae of the Atlantic flyway. 1. Massachusetts. PMID- 4215893 TI - Simulated field blood studies in the bottle-nosed dolphin Tursiops truncatus. 3. Changes in hematology and chemistry during blood and plasma storage. PMID- 4215895 TI - Avian hematozoa of some Ugandan birds. PMID- 4215896 TI - [Changes of susceptibility of anaerobes to various antibiotics (author's transl)]. PMID- 4215897 TI - [Clinical experience with amikacin (BB-K8) (author's transl)]. PMID- 4215898 TI - [Laboratory and clinical investigation of amikacin (BB-K8) (author's transl)]. PMID- 4215899 TI - [Laboratory and clinical studies on amikacin (BB-K8) (author's transl)]. PMID- 4215900 TI - [Fundamental and clinical studies on BB-K8 (amikacin), a new semisynthetic aminoglycoside antibiotic (author's transl)]. PMID- 4215901 TI - [Treatment of otorhinolaryngological infections with BB-K8 (author's transl)]. PMID- 4215902 TI - [Clinical experience with amikacin (BB-K8) in the urological field (author's transl)]. PMID- 4215903 TI - [Studies on amikacin (BB-K8) (author's transl)]. PMID- 4215904 TI - [Studies on a new aminoglycoside antibiotic, amikacin (BB-K8) in pediatrics (author's transl)]. PMID- 4215905 TI - Antigenicity of bicyclomycin and its cross-reactivity with benzylpenicillin. PMID- 4215906 TI - [Minimum inhibitory concentration of lividomycin for gonococci and its clinical effect in gonorrhea (author's transl)]. PMID- 4215907 TI - [Laboratory study on the sensitivity disks used for the large dosis therapy of sulbenicillin (author's transl)]. PMID- 4215908 TI - [Hypothalamic and hypophyseal hypothyroidism--diagnosis based on thyrotropin releasing hormone test]. PMID- 4215909 TI - [Isolated thyrotropin releasing hormone deficiency]. PMID- 4215910 TI - [Purification of an active adjuvant substance from Mycobacterium tuberculosis]. PMID- 4215911 TI - [Purification and application of tuberculosis adjuvants]. PMID- 4215912 TI - Skin reaction produced by endotoxins and lactobacillus in mouse. PMID- 4215913 TI - Preparation and characterization of the monospecific antiserum directed to the ninth component of human complement (C9). PMID- 4215914 TI - Corneal ulcers caused by protease and elastase from Pseudomonas aeruginosa. PMID- 4215915 TI - Letter: Elevation of serum C9 level associated with Behcet disease. PMID- 4215916 TI - [Thyrotropin releasing hormone test in chronic renal failure]. PMID- 4215917 TI - Studies on methods for evaluation of anticoccidial drugs in vitro. PMID- 4215918 TI - Yersinia pseudotuberculosis infection occurred spontaneously in a group of patas monkeys (Erythrocebus patas). PMID- 4215919 TI - Experimental studies on glucuronidation. III. UDP-glucuronyltransferase activity and glucuronide excretion enhanced by oral administration of eugenol. PMID- 4215920 TI - [Adrenochrome conjunctival inclusions following a local adrenaline therapy (author's transl)]. PMID- 4215921 TI - [Norrie's disease]. PMID- 4215922 TI - [Viral heart diseases]. PMID- 4215923 TI - [Role of bacillus pyocyaneus in the pathology of the internal organs]. PMID- 4215924 TI - The osteochondral junction of mammalian joints. An ultrastructural and microanalytic study. PMID- 4215925 TI - A scanning electron microscopic study of gallstone development in man. PMID- 4215927 TI - Positional information in unicellular organisms. PMID- 4215926 TI - Dietary fibre in human nutrition. PMID- 4215928 TI - Aging and long-term temporal regulation in ciliated protozoa. A critical review. PMID- 4215929 TI - [A new, organ-specific antibody in the course of chronic hepatitis]. PMID- 4215930 TI - [Bronchial lavage: significance and value in search for Koch's bacillus]. PMID- 4215931 TI - [Asthma therapy using the inhalation method]. PMID- 4215932 TI - [Rehabilitation of coronary patients]. PMID- 4215934 TI - [Combined TRF (thyreotropin-releasing factor) and LRF (luteotropin-releasing factor) stimulation test. Comparative studies on separate procedures]. PMID- 4215935 TI - [Evaluation of serum alpha-antitrypsin deficiency]. PMID- 4215933 TI - Properties of palmityl-CoA: L-alpha-glycerolphosphate acyl transferase from bovine mammary microsomes. PMID- 4215936 TI - [Thyroid response to an infusion of thyrotropin releasing hormone (TRH) in normal men]. PMID- 4215937 TI - Brucellosis in the United States, 1960-1972. An abattoir-associated disease. Part I. Clinical features and therapy. PMID- 4215938 TI - Biphasic adrenergic responses of rabbit aorta. PMID- 4215939 TI - Absorption and excretion of amoxycillin and pivampicillin, two new semisynthetic penicillins. PMID- 4215940 TI - Letter: Psychosis associated with sympathomimetic and cromoglycate therapy. PMID- 4215941 TI - Usefulness of rheophoresis for detection of Australia antigen. PMID- 4215943 TI - [Blood concentrations of different oral penicillin suspensions on the market (author's transl)]. PMID- 4215942 TI - [Letter: Substitution therapy following surgery of a hypophyseal neoplasm]. PMID- 4215944 TI - Multiple loop inoculator as an aid in bacteriocine typing techniques. PMID- 4215945 TI - A comparative study of the fluorescent treponemal antibody-absorbed test and some existing methods available for the serological diagnosis of syphilis. PMID- 4215946 TI - Calculations pertaining to the use of fast (equal to or less than 50-MeV) neutrons in cancer radiotherapy. PMID- 4215947 TI - Experimental and calculated bremsstrahlung spectra from a 25-MeV linear accelerator and a 19-MeV betatron. PMID- 4215948 TI - Measurements of electron-beam energy with rapid-processed film. PMID- 4215950 TI - Clinical parameters of high energy linear accelerators. PMID- 4215949 TI - Downtime experience for clinical linear accelerators. PMID- 4215951 TI - Restriction and modification in B. subtilis. Biological aspects. PMID- 4215952 TI - Host controlled modification and restriction in Bacillus subtilis. PMID- 4215953 TI - Mature DNA from temperate bacillusphage phi105 requires primary recombination to be infectious in transfection. PMID- 4215954 TI - Relationship between the nature of the nucleotide sequence and the degree of asymmetry of the complementary strands of DNA in microorganisms. PMID- 4215955 TI - Matrix activity of the X chromosomes of male and female drosophilas in the synthesis of RNA by bacterial RNA-polymerase. PMID- 4215956 TI - [The ecology of animal parasites and zooparasitic diseases of man (author's transl)]. PMID- 4215957 TI - [Tape worm infections of man and their therapy (author's transl)]. PMID- 4215958 TI - [American leishmaniasis of the skin and mucous membranes and its treatment with amphotericin B (author's transl)]. PMID- 4215959 TI - [Investigations on the occurrence of disease in the plantation populations of Ceylon (author's transl)]. PMID- 4215960 TI - [Medicamentous prophylaxis of postoperative cardiovascular complications (author's transl)]. PMID- 4215961 TI - [Effect of kavain on alcoholic patients in the withdrawal phase (author's transl)]. PMID- 4215962 TI - [Experience with a combination preparation for the treatment of urinary tract infections]. PMID- 4215963 TI - [Klinefelter's syndrome. Clinical, psychiatric and cytogenetic findings in 28 cases]. PMID- 4215964 TI - [Human chorion somatomammotropin (placenta lactogen). Biochemical, physiological and clinical aspects (author's transl)]. PMID- 4215965 TI - [Present aspects of bone marrow lesions due to drugs (author's transl)]. PMID- 4215966 TI - [Pulmonary emphysema. Classification from the clinical, radiological and functional points of view (author's transl)]. PMID- 4215967 TI - [A suggestion for mass examinations for the prevention of pneumopathies (author's transl)]. PMID- 4215969 TI - [In memoriam Mario Cardia (1898-1974)]. PMID- 4215968 TI - [The irritable colon. A retrospective study of 217 cases (author's transl)]. PMID- 4215970 TI - Investigations on radiosensitive and radioresistant populations of Drosophila melanogaster. V. Relations between the relative radioresistance and some recombination properties in the irradiated population ROI. PMID- 4215971 TI - The induction of temperature-sensitive mutations in Drosophila melanogaster by the acridine mustard ICR-170. PMID- 4215974 TI - Detoxification of long-term methadone patients. PMID- 4215973 TI - Clinical evaluation of antibody sensitized latex particles method for Australia antigen in serum. PMID- 4215972 TI - Endotoxic substance of Cryptococcus neoformans. PMID- 4215975 TI - Myth versus fact in long term methadone maintenance treatment: the community's viewpoint. PMID- 4215976 TI - Significance of hypermacroglobulinemia in methadone maintained and other narcotic addicts. PMID- 4215977 TI - New choices for methadone maintenance patients: planned, voluntary long-term detoxification. PMID- 4215978 TI - Methadone and naloxone in combination (Naldone) for the treatment of heroin addicts. PMID- 4215980 TI - Beta alanine and cuticle maturation in Drosophila. PMID- 4215979 TI - Identification of metabolic dechlorination of highly chlorinated biphenyl in rabbit. PMID- 4215981 TI - Purification and properties of protease produced by Staphylococcus aureus strain SH-91 isolated from diseased chickens. PMID- 4215983 TI - [Letter: Anti-rhesus(D) immunoprophylaxis in abortion]. PMID- 4215982 TI - [Subtotal resection of the small intestine. The possibilities of long term parenteral feeding via an arteriovenous shunt]. PMID- 4215984 TI - [Pigeon breeders' disease]. PMID- 4215985 TI - [Congenital obstruction of the superior sagittal sinus--a case report (author's transl)]. PMID- 4215987 TI - Response variables and motor slow cortical potentials (SCP) during performance of learned movements in the squirrel monkey (Saimiri sciureus). PMID- 4215986 TI - Ovulation induced by norepinephrine in rats made anovulatory by various experimental procedures. PMID- 4215988 TI - [Blood platelet qualitative defects]. PMID- 4215989 TI - [Diet therapy and parenteral feeding in some malabsorption syndromes]. PMID- 4215990 TI - [Dermopathies, dietetics and gastroenteropathies]. PMID- 4215991 TI - [Current status of cerebrospinal meningitis]. PMID- 4215992 TI - Correlation conferences in radiology and pathology: osseous lesions in adolescence with known neurofibromatosis. PMID- 4215993 TI - Value of HCS determinations in management of prolonged pregnancy. PMID- 4215994 TI - In vitro studies of human ovarian contractility. PMID- 4215995 TI - Lactobacilli of infected dental root canals. PMID- 4215996 TI - Spontaneous tumours in amphibia. A review. PMID- 4215997 TI - Chronic secretory otitis media--long-term results after treatment with grommets. PMID- 4215998 TI - [Scoliosis in neurofibromatosis]. PMID- 4215999 TI - [Methods for the determination of thyrotropin releasing hormone. II. In-vitro method]. PMID- 4216000 TI - [A compative study of electro-immunodiffusion and radial immunodiffusion with application to the determination of immunoglobulins]. PMID- 4216001 TI - [Appearance of antibodies to one of the general antigens of microorganisms of the intestinal group after administration to animals of carcinogenic substances and in anacid gastritis in man]. PMID- 4216002 TI - DDT plus PCB'S in blubber of harbor seals. PMID- 4216003 TI - Chlorinated hydrocarbon and mercury residues in wookcock in the United States, 1970-71. PMID- 4216004 TI - Selected chlorinated hydrocarbons in bottom material from streams tributary to San Francisco Bay. PMID- 4216006 TI - Experimentally induced periapical inflammation in permanent and primary teeth of monkeys. PMID- 4216005 TI - Organochlorine residues in golden eagles, United States--March 1964-July 1971. PMID- 4216007 TI - Prolonging life by mechanical means--the role of the nurse. PMID- 4216008 TI - Socio-economic disease. PMID- 4216009 TI - Editorial: Longstay problems. PMID- 4216010 TI - Tuberculosis in Africans. Prolonged observations on drug sensitivity of M. tuberculosis during chemotherapy. PMID- 4216011 TI - [Hepatic damage in patients treated with rifampicin (author's transl)]. PMID- 4216013 TI - [Complement fixation test technics in the diagnosis of cattle brucellosis. II. An attempt at modifying the official technics]. PMID- 4216012 TI - [Complement fixation test technics in the diagnosis of cattle brucellosis. I. Effect of time and temperature on sensitivity of the test]. PMID- 4216014 TI - [Intravenous infusions of lipid emulsions in children]. PMID- 4216015 TI - [The use of brinerdin in the long-term treatment of moderate essential hypertension (author's transl)]. PMID- 4216016 TI - Prevention and future control of hospital-associated infections commonly caused by gram-negative bacteria. PMID- 4216017 TI - An inhibitor of cell proliferation released by cultures of macrophages. AB - Culture fluids from mouse peritoneal exudate cells inhibited [(3)H]thymidine incorporation by, and proliferation of, EL-4 leukemia cells, 3T3 cells, and mitogen-stimulated spleen lymphocytes. Inhibited EL-4 leukemia cells recovered their normal proliferative capacity when washed and incubated in normal medium. The inhibitory activity resided in a low-molecular-weight substance that could be absorbed by incubation with the tumor cells. This substance was dialyzable and resistant to tryptic digestion and phosphodiesterase treatment. The mononuclear phagocytes in the peritoneal exudate seemed to be the source of the inhibitor. The inhibitory material was found in the same amounts in exudates of normal mice or mice injected with peptone or infected with Listeria monocytogenes; spleen cells adherent to plastic released the inhibitor but in lesser amount. We suggest that this inhibitor may contribute to the deleterious effects found when various cells, including neoplastic ones, are cultured in the presence of macrophages. PMID- 4216018 TI - Pyrrole hydrogen ionization of imidazole derivatives in metal ion complexes and carbonic anhydrase. AB - Zinc ion-induced pyrrole hydrogen ionization from a histidyl residue has recently been suggested as the source of the activity-related deprotonation in carbonic anhydrase (EC 4.2.1.1; carbonate hydro-lyase) occurring at pH 7-8. The results offered to support the hypothesis are shown to be deficient. Examination of the literature reveals no precedent for such a pronounced acidification from pK(a) [unk] 14.2 in imidazole compounds by zinc ion. It is suggested that Zn(II) induced pyrrole ionizations in imidazoles occur with pK(a) about 13. PMID- 4216019 TI - Viable molecular hybrids of bacteriophage lambda and eukaryotic DNA. AB - A bacteriophage lambda strain has been constructed and a method developed by which DNA from potentially any source can be covalently inserted through EcoRI cohesive ends into the middle of the lambda DNA. These hybrid DNAs can infect nonrestricting Escherichia coli cells and can then propagate as plaque-forming phage. A unique feature of this lambda strain is that extra DNA in the middle of its genome is required for plaque formation. A large number of such phages have been produced with E. coli DNA and Drosophila melanogaster DNA. PMID- 4216020 TI - Restriction endonuclease cleavage maps of animal mitochondrial DNAs. AB - The restriction endonuclease, HindIII, gives rise to three fragments in each of the three mitochondrial DNAs isolated from the established mammalian cell lines LA9 (mouse), HeLa (human), and BSC-1 (African green monkey). The restriction endonuclease, EcoRI, gives rise to three fragments in mitochondrial DNA from HeLa and to two in DNAs from LA9 and BSC-1. The sizes and the orders of the fragments in the respective genomes have been determined with data obtained from the electron microscope. The origin and the direction of replication have been designated in each of the cleavage maps. Polyacrylamide gel electrophoretic analyses demonstrated that additional fragments not detectable in the electron microscope and larger than 50 nucleotide pairs were not present. PMID- 4216021 TI - Fluorescence enhancement of laccase induced by reduction of Cu(II) sites. AB - The intrinsic fluorescence of laccase (p-diphenol:O(2) oxidoreductase, EC 1.10.3.2), emitted by its tyrosinyl and tryptophanyl residues, underwent significant enhancement upon reduction of the enzyme redox sites. The increase in quantum yield reached its maximum after the addition of approximately four reduction equivalents and depended on the wavelength of excitation:54% increase for lambda(ex) = 250 nm and 76% for lambda(ex) = 305 nm.A linear correlation between this enhancement and the reduction of the type 1 Cu(II) was observed both by direct measurement and by calculation on the basis of added reductant. The implications of the fluorescence enhancement and its correlation with the reduction of the type 1 copper are discussed in terms of the possible quenching mechanisms. The possibility of a redox-induced structural transition in the protein is suggested. PMID- 4216022 TI - Preparation and spectroscopic studies of cobalt(II) derivatives of blue copper proteins. AB - Preparation of cobalt(II) derivatives of type 1 copper proteins has been extended to include bean plastocyanin and azurin from Pseudomonas aeruginosa. Fluorescence quenching data suggest that Co(II) binds to the type 1 site of both apoplastocyanin and apoazurin. Electronic absorption spectral measurements have been made for cobalt(II)-stellacyanin, cobalt(II)-plastocyanin, and cobalt(II) azurin. In each case two visible bands with moderate intensities and two rather strong ultraviolet absorption peaks are observed. The intensity pattern and the separation of the two ultraviolet bands in the Co(II) derivatives correspond closely to the two intense, low-lying absorption peaks in the analogous, type 1 copper proteins. The evidence suggests that the intense, two-band systems represent ligand-to-metal charge transfer transitions in both Cu(II) and Co(II) derivatives. It is proposed that the transitions in each case originate in the 3ppi and 3psigma orbitals of a cysteine sulfur ligand at the type 1 site. The visible absorption bands in the Co(II) derivatives are assigned to d-d transitions. The large (4)P splitting observed indicates that the type 1 Co(II) site is of low symmetry. The d-d band pattern suggests that the high-spin Co(II) center is either distorted tetrahedral or five-coordinate. The observed band intensities are in much closer accord with the values for Co(II) complexes known to have distorted tetrahedral structures. PMID- 4216023 TI - Isolation of DNA-membrane complex in Bacillus subtilis. AB - A DNA-membrane complex of Bacillus subtilis was separated from the bulk of the membrane by CsCl-sucrose double gradient centrifugation. The complex has a CsCl sucrose buoyant density of 1.35-1.45 g/cm(3). Gel electrophoretic analyses show that the complex has about 5% of the whole membrane proteins and contains proteins unique to the complex as well as a small amount of membrane proteins. DNA in the complex is enriched for a genetic marker close to the origin (pur A16) and for one near the terminus (metB5). Artifactual formation of the complex during the lysate preparation was shown to be unlikely. PMID- 4216024 TI - Chloramphenicol restores sigma factor activity to sporulating Bacillus subtilis. AB - The sigma subunit of RNA polymerase from sporulating Bacillus subtilis is markedly inhibited in its ability to direct active transcription of phage varphie DNA in vitro. Treatment of sporulating bacteria with chloramphenicol rapidly restores sigma activity, suggesting that sporulating cells contain an inhibitor of sigma that is physiologically unstable or that becomes unstable after drug treatment. The hypothetical inhibitor is depleted exponentially with an apparent half-life of 11 min at 37 degrees . PMID- 4216025 TI - The effects of increased temperature on electroretinograms of temperature sensitive paralysis mutants of Drosophila melanogaster. AB - Mutations within the shibire locus of Drosophila melanogaster are non complementing alleles which result in reversible paralysis at 29 degrees but retention of normal locomotor behavior at 22 degrees . Electroretinograms of six of the mutants have been recorded at various temperatures. Two changes occurred in the electroretinograms of flies carrying most of the alleles at high temperature: they lost the "on"- and "off"- transients of the normal electroretinogram, and the fast decay of the receptor potential was attenuated. For flies with four of the alleles, a base-line oscillation was also observed. Analysis of electroretinograms of mosaic shibire flies indicates that the loss of the transients can be attributed to both a pre-synaptic and a post-synaptic effect. PMID- 4216026 TI - Sequence homology between the RNA of Mason-Pfizer monkey virus and the RNA of human malignant breast tumors. AB - Radioactive DNA ([(3)H]cDNA) complementary to the RNA of Mason-Pfizer monkey virus was used in molecular hybridization experiments to demonstrate sequence homology between its viral RNA and RNA of human malignant breast tumors. Hybridization products were analyzed by cesium sulfate equilibrium density centrifugation and hydroxylapatite chromatography. Seven of ten human malignant breast tumors tested contained virus-related RNA when assayed by hydroxylapatite chromatography, whereas no sequence homology was found in RNA from 11 human benign breast tumors or from RNA of normal human spleen, liver, or kidney. Hybridizations between [(3)H]cDNA of the monkey virus and human breast adenocarcinoma RNA showed a C(r)t((1/2)) of about 2 x 10(4). The fidelity of the hybrids formed was indicated by a T(m) of 80.5 degrees . PMID- 4216027 TI - Kinetic constants determined from membrane transport measurements: carbonic anhydrase activity at high concentrations. AB - Facilitated diffusion rates can be used to determine kinetic constants for rapid reactions occurring within membranes and thin fluid layers. We have applied this technique to the study of the reversible CO(2) hydration reactions catalyzed by carbonic anhydrase (EC 4.2.1.1; carbonate hydro-lyase). The experimental method entails the diffusion of tracer (14)CO(2) through Millipore filter membranes impregnated with aqueous bicarbonate solutions containing various concentrations of dissolved enzyme. A mathematical model of the simultaneous diffusion/reaction transport process is analyzed to predict the effective diffusion rate in terms of the relevant kinetic parameters. The solution to the mathematical model can be transformed to yield straight-line relations analogous to Lineweaver-Burk plots. The pseudo-first-order enzymatic rate constant for the hydration reaction can be determined from the slope or intercept of a plot of this straight-line relationship. Rate constants were accurately measured at high enzyme concentrations for reactions having half-times under a millisecond. The rate constants agree well with other reported kinetic constants for carbonic anhydrase, and the known pH-activity dependence and bicarbonate inhibition are quantitatively demonstrated. The specific activity is constant up to 4.0 mg/ml, which is believed to be the highest concentration at which the activity has been measured. The membrane transport technique has general applicability for other rapid reaction systems. PMID- 4216028 TI - Differentiation of lens-like structures from newt iris epithelial cells in vitro. AB - Dissociated cells of pigmented iris epithelium from adult newts grew intensively in monolayer cultures after a lag of two to three weeks. During the lag period, depigmentation occurred in many cells. When cultures became confluent five to six weeks after seeding, many tiny lens-like structures (30-70 per plate) differentiated from dense foci of amelanotic epithelial cells. These lens-like structures appeared in all cultures originated from cells of ventral as well as dorsal iris. The identification of these structures as lens was established by both immunological and ultrastructural techniques. PMID- 4216029 TI - Abnormal solubilization by triton X-100 of erythrocyte membranes from patients with paroxysmal nocturnal hemoglobinuria. PMID- 4216031 TI - Cholesterol absorption in primates as determined by the Zilversmit isotope ratio method. PMID- 4216030 TI - Electrophoretic evaluation of various procedures for solubilizing erythrocyte membranes. PMID- 4216032 TI - Immunological studies of thrombopoietin. PMID- 4216033 TI - Fletcher factor activity in plasmas of various species. PMID- 4216034 TI - The synthesis of taurine from sulfate. VIII. A constitutive enzyme in mammals. PMID- 4216035 TI - Immune and nonimmune gel precipitates produced by honey bee venom and its components. PMID- 4216036 TI - Standardized production in goats of antilymphocyte globulin and its clinical use. PMID- 4216039 TI - Perceptual generalization: a note on the peak shift. PMID- 4216037 TI - [The roll of prostaglandins and catecholamines in inflammation and in the mode of action of antiphlogistics]. PMID- 4216038 TI - Discrimination learning differences and similarities as a function of brain index. PMID- 4216040 TI - [Comparison of biological effectiveness of 20 Mev electrons and 200 kv X-ray radiation by the appearance of chromosome aberrations in the cells of Ehrlich tumor]. PMID- 4216041 TI - Immunologic considerations of carcinoma of the prostate. PMID- 4216042 TI - Significance of paraproteins in neoplastic disease. PMID- 4216043 TI - Biological effects during space flights. PMID- 4216044 TI - Biological effects of gravitational fields. PMID- 4216046 TI - [Chemistry of immunoglobulin A (author's transl)]. PMID- 4216045 TI - [Chemistry and biology of immunoglobulin M (author's transl)]. PMID- 4216047 TI - [Target cell destruction by sensitized lymphocytes (author's transl)]. PMID- 4216048 TI - [Attempted protection of mice with micro-doses of tubercle bacilli]. PMID- 4216049 TI - [Hypopotassemia in parenteral hyperalimentation]. PMID- 4216050 TI - [Behavior of the 3rd and 4th complement fractions in chronic hepatitis]. PMID- 4216051 TI - [Intestinal malabsorption due to multiple diverticulosis of the duodenum and the small intestine. Report of 1 case]. PMID- 4216052 TI - [Study of the immunostimulating activity of 3 imidazole derivatives with anthelminthic action, on bovipestic, peripneumonic and anthrax immunogenesis]. PMID- 4216053 TI - [Helminths (and various other parasites) of dromedary in Ethiopia]. PMID- 4216054 TI - Perceptual learning ability in Mandrillus sphinx and Cercopithecus nictitans. PMID- 4216055 TI - Glycogen synthetase activity in the sea mussel (Mytilus edulis, l.). PMID- 4216056 TI - Purification of frog muscle glycogen synthetase. PMID- 4216057 TI - O-diphenol:oxygen-oxidoreductase from Musa cavendishii. PMID- 4216058 TI - Blood flow metabolism couple in brain. PMID- 4216059 TI - Cannabinol-7-oic acid: a metabolite of delta1-tetrahydrocannabinol in the rhesus monkey. PMID- 4216060 TI - The uterotropic activity of commercial and isomerically-pure chlorobiphenyls in the rat. PMID- 4216061 TI - Increased half-life of rat liver RNA following dietary administration of 3' methyl-4-dimethylaminoazobenzene and/or chloramphenicol. PMID- 4216062 TI - [Diagnostic and therapeutic problems of optic nerve and optic chiasm tumors in children showing signs of cutaneous neurofibromatosis. Apropos of a case]. PMID- 4216064 TI - [Carcinoma and multiple calculi in diverticulum of the female urethra]. PMID- 4216063 TI - [Meningioma of sella turcica tuberculum and Recklinghausen's neurofibromatosis. Apropos of an infantile form]. PMID- 4216065 TI - [Preliminary diagnosis of Pseudomonas aeruginosa presence in food]. PMID- 4216066 TI - [Effect of selected pesticides on the activity of cytochrome P-450 and UDP glucuronyltransferase in vitro]. PMID- 4216067 TI - [Determination of organophosphorus and carbamate insecticides by the kinetic enzymatic method]. PMID- 4216068 TI - [Epileptic seizures and traumatic epilepsies]. PMID- 4216069 TI - [Anomalies of the lumbar vertebrae and of the sacrum associated with a cul-de-sac malformation of the dura mater in Recklinghausen's disease. Apropos of a case]. PMID- 4216070 TI - [Light-chain myeloma and osteomalacia]. PMID- 4216071 TI - [Serodiagnosis of infectious anemia in perissodactyla (AIE). (A solved problem)]. PMID- 4216072 TI - The coordination of eye-head movements. PMID- 4216073 TI - Aerial dispersal of micro-organisms from the human respiratory tract. PMID- 4216074 TI - Effects of soaps, germicides and disinfectants on the skin flora. PMID- 4216075 TI - Arrhinencephaly in aberrations of autosomal chromosomes and sequential chromosomal functional expression. PMID- 4216077 TI - Experiments on the antimutagenic effect of AET (beta-aminoethylisothiuronium bromide) in Drosophila melanogaster. PMID- 4216076 TI - Effect of mutagens on MS2 phage and its infectious RNA. Communication III. Action of o-methylhydroxylamine and analysis of inactivation kinetics. PMID- 4216078 TI - Nonhomologous chromosome pairing in oogenesis of XXY females of Drosophila melanogaster. Communication I. Nonhomologous pairing X-Y, X-2, Y-2, in XXY females; Cy-Xa. PMID- 4216079 TI - Intensity of chemical mutagenesis in human cells as a function of age and sex. PMID- 4216080 TI - Study of the rate of development of Drosophila heterozygous with respect to radio induced mutations. PMID- 4216081 TI - A study of the homeotic genes antennopedix and nasobemia in Drosophila melanogaster. Communication III. Influence of temperature on the penetrance and expressivity of the Apx and Ns genes. PMID- 4216082 TI - Effect of mutagens on MS2 phage and its infectious RNA. Communication IV. Effect of O-methylhydroxylamine. Analysis of mutagenesis kinetics. PMID- 4216083 TI - Differential effect of Bacillis subtilis extracts on transformation with nonirradiated and UV-irradiated DNA. PMID- 4216084 TI - [Cannulation of the inferior vena cava as the last posibility of a venous approach]. PMID- 4216085 TI - Letter: Side-effects of maprotiline. PMID- 4216086 TI - [Letter: Ketoacidotic coma]. PMID- 4216087 TI - Lactic acidosis in diabetics. PMID- 4216088 TI - The nature and frequency of rugby injuries: a pilot study of 300 injuries at Stellenbosch. PMID- 4216089 TI - Detection of bladder-cancer-associated antigens in urine by micro-complement fixation. PMID- 4216090 TI - Reversal of seconardy lesions of diabetes in rats by pancreatic islet transplantation. PMID- 4216092 TI - Tissue culture of adult human islets of Langerhans for transplantation. PMID- 4216091 TI - Physiologic and immunologic status of long-functioning transplanted pancreatic islets in rats. PMID- 4216093 TI - Enhancement of pancreatic islet allograft survival with ALS and donor bone marrow. PMID- 4216094 TI - Prolonged relief from diabetes after syngeneic or allogeneic transplantation of isolated pancreatic islets in rats. PMID- 4216095 TI - Edema formation and central hemorrhagic necrosis following impact injury to primate spinal cord. PMID- 4216096 TI - Wound healing and collagen degradation in calcium-EDTA-treated rats. PMID- 4216097 TI - Histopathologic observations of labyrinthitis ossificans. PMID- 4216098 TI - Casein hydrolysate and Intralipid vs casein hydrolysate and 25 percent glucose for hyperalimentation. PMID- 4216099 TI - Arterial plasma amino acids in patients receiving an elemental diet. PMID- 4216100 TI - The demands of hyperalimentation on splanchnic blood flow and oxygen consumption. PMID- 4216101 TI - Intravenous hyperalimentation and growth hormone in cancer patients. PMID- 4216102 TI - Fat-carbohydrate interaction: effects on nitrogen-sparing in total intravenous feeding. PMID- 4216103 TI - Effect of parenteral nutrition on body composition. PMID- 4216105 TI - 4th Symposium on oral sensation and perception. Concluding comment I. PMID- 4216104 TI - Effect of taste on ingestion by human newborns. PMID- 4216107 TI - [Treatment of obstructive lung diseases with a new preparation--disodium cromoglycate (Intal)]. PMID- 4216106 TI - [Immunoglobulins and complement in systemic lupus erythematosus, rheumatoid arthritis and juvenile rheumatoid arthritis]. PMID- 4216108 TI - [Injuries by poisonous animals]. PMID- 4216109 TI - [Interaction of hospital and family doctor in the differential therapy of leukemia in adults]. PMID- 4216110 TI - [Aspirin--an always new drug]. PMID- 4216111 TI - [The effects of nitrite compounds in angina pectoris (author's transl)]. PMID- 4216112 TI - [Value of principle component analysis in the study of therapeutic agents. Application in long-term treatment of osteoporosis using low calcitonin dosage]. PMID- 4216113 TI - [Testing of various thromboplastins. Possibilities of standardization]. PMID- 4216115 TI - [Congenital dysfibrinogenemia. Report on a new family (fibrinogen "Wiesbaden")]. PMID- 4216114 TI - [Identification and preparation of high-molecular derivatives of fibrinogen from human plasma by means of PAA-gel electrophoresis and agarose-gel chromatography]. PMID- 4216116 TI - Molecular aspects of the clottable proteins of human plasma during fibrinogenolysis. PMID- 4216117 TI - Conditions for stabilization and determination of activated factor V. PMID- 4216118 TI - [Lympho-reticuloproliferative diseases--problems of differential diagnosis]. PMID- 4216119 TI - [Myelomatosis]. PMID- 4216120 TI - A rapid and reliable micro-method of leukoagglutination using papain. PMID- 4216121 TI - Influence of calcium and magnesium ions on the sino-atrial node pacemaker activity of the canine heart. PMID- 4216123 TI - [Neutrons for medical use, yes or no?]. PMID- 4216122 TI - Characterization of the venoms of various Bothrops species by immunoelectrophoresis and reaction with fibrinogen agarose. PMID- 4216124 TI - [Neutron generators for radiotherapy]. PMID- 4216125 TI - Radiotherapy combined with hormone therapy for prostate cancer. PMID- 4216126 TI - [Deep electron therapy in the thoracic area. III. Dosimetric studies using symmetrical pendulum irradiation over the lateral thoracic wall]. PMID- 4216127 TI - [Deep electron therapy in the thoracic area. IV. Pendulum irradiation using an asymmetrical pendulum angle]. PMID- 4216128 TI - [Simple method for energy measurement in medically-used electron accelerators]. PMID- 4216129 TI - [Immunochemical analysis of ultrasonic fractions of chromatin]. PMID- 4216130 TI - Renal clearance studies in the pig. Surgical procedures, performance of investigations and physiological data. PMID- 4216131 TI - The significance of the bacterial count in pyelonephrititis due to Pseudomonas aeruginosa in animal experiments. PMID- 4216132 TI - [Outcomes of plastic surgery on the eyelids, conjunctival cavity and eye socket in children and adolescents]. PMID- 4216133 TI - Radiologic examination of the esophagus in dogs and cats. PMID- 4216134 TI - Radiographic contrast studies of the lower urinary tract. PMID- 4216135 TI - Indications and selection of patients for radiation therapy. PMID- 4216136 TI - Toad venom toxicity and its clinical occurrence in small animals in the United Kingdom. PMID- 4216137 TI - [Exophageal hiatal hernia in conjunction with cicatricial stenosis and epiphrenic esophageal diverticulum]. PMID- 4216138 TI - Enterochromaffin cells of the mammalian small intestine as the source of motilin. PMID- 4216140 TI - Prevention of D-galactosamine-induced hepatocellular autophagocytosis by cycloheximide. PMID- 4216139 TI - Desmosomes in human seminiferous epithelium. An electron microscopic study. PMID- 4216141 TI - Experimental modification of the mitogenic effect of methyl sterculate on rat liver. PMID- 4216142 TI - Effects of uremia and vitamin D on bone and the ultrastructure of thyroid parafollicular cells and parathyroid chief cells in the rat. PMID- 4216143 TI - Fetal hemopoiesis. II. Electron microscopic studies on human hepatic hemopoiesis. PMID- 4216144 TI - The permeability of the blood-testis barrier to lanthanum during the immune induced aspermatogenesis and following vasectomy in the guinea-pig. PMID- 4216145 TI - [Our experience with the Effective Thyroxine Ratio test (ETR) IN THE Differential diagnosis of functional thyroid gland disorders]. PMID- 4216146 TI - [Content of blood serum immunoglobulins in healthy children]. PMID- 4216147 TI - [Skin manifestations in diphtheria carriers]. PMID- 4216148 TI - [Thiophosphamide kinetics in the blood of breast cancer patients]. PMID- 4216149 TI - [Clinical biochemical data in cancer of the gastric stump]. PMID- 4216150 TI - [Late results of observing patients with extensive breast cancer who have undergone chemotherapy by infusion]. PMID- 4216151 TI - [Blood changes in hyperthermic perfusion with chemotherapeutic preparations]. PMID- 4216152 TI - [Intra-arterial chemotherapy in stomach cancer]. PMID- 4216153 TI - [Use of fast electrons in the radiation therapy of malignant neoplasms]. PMID- 4216154 TI - [Serum enzymatic spectrum in breast cancer patients in the process of complex chemo- and radiotherapy]. PMID- 4216155 TI - [Antitumor action of berberinol thiophosphamide in experimental tumors in mice]. PMID- 4216156 TI - [Determination of 3-oxyanthranilic acid as a hapten in the blood of workers coming in contact with aniline dyes]. PMID- 4216157 TI - [Chemotherapy in inoperable stomach cancer]. PMID- 4216158 TI - [Comparative study of the hemagglutinating activity of various strains of the rubella virus]. PMID- 4216159 TI - [Dynamics of the synthesis of tick-borne encephalitis virus antigen by cell cultures of varying origins according to immunofluorescence data]. PMID- 4216160 TI - [Contaminamts of cell cultures]. PMID- 4216161 TI - [Properties of the A-particles isolated from the cells of continuous human lines]. PMID- 4216162 TI - [Reproduction of the Venezuelan equine encephalomyelitis virus under conditions of low ionic strength]. PMID- 4216163 TI - [Comparison of test systems for B-type oncornaviruses isolated from HEp-2 human laryngeal carcinoma cells and from D6 human bone marrow cells]. PMID- 4216165 TI - [Intravascular denaturation of plasma proteins in a patient with IgM paraproteinaemia following the intravenous administration of a bile-excreted x ray contrast medium (author's transl)]. PMID- 4216164 TI - [Role of Coxsackie A21 viruses in common cold diseases and their complications]. PMID- 4216167 TI - [Septicaemia following early tangential excision of burns (author's transl)]. PMID- 4216166 TI - [Chemical and biochemical aspects of the releasing hormones (author's transl)]. PMID- 4216168 TI - [The effect of nitroglycerin on the regional myocardial blood flow in man (author's transl)]. PMID- 4216169 TI - The planning of medical education programmes. Report of a WHO Expert Committee. PMID- 4216170 TI - Planning and organization of geriatric services. Report of a WHO Expert Committe. PMID- 4216171 TI - WHO Expert committe on Malaria.. Sixteenth report. PMID- 4216172 TI - WHO Expert Committee on Drug Dependence. Twentieth report. PMID- 4216173 TI - WHO Expert Committee on Tuberculosis. Ninth report. PMID- 4216174 TI - Ecology and control of rodents of public health importance. Report of a WHO Scientific Group. PMID- 4216175 TI - Detection of dependence-producing drugs in body fluids. Report of a WHO Meeting of Investigators. PMID- 4216176 TI - Evaluation of certain food additives. Eighteenth Report of the Joint FAO/WHO Expert Committee on Food Additives. PMID- 4216177 TI - Community health nursing. Report of a WHO Expert Committee. PMID- 4216178 TI - New approaches in health statistics. Report of the Second International Conference of National Committees on Vital and Health Statistics. PMID- 4216179 TI - [The diencephalon-hypophyseal system. Control mechanisms of endocrine regulation]. PMID- 4216180 TI - [Differential treatment of coronary heart disease]. PMID- 4216181 TI - [Errors and hazards of blood transfusion and their prevention]. PMID- 4216182 TI - [Experiences in dispensatory care for patients with epileptic attacks]. PMID- 4216183 TI - [Simultaneous thin-layer chromatography of blood and urine samples for the diagnosis of hereditary amino acid metabolism disorders]. PMID- 4216184 TI - [The effect of cross-sectional changes in lung circulation on human pulmonary artery pressure]. PMID- 4216185 TI - [Intramural microdiverticulosis of the esophagus]. PMID- 4216186 TI - [Current status of our knowledge on the tolerance of enzyme detergents during production and consumption]. PMID- 4216187 TI - [Peritoneal dialysis for the treatment of respiratory distress syndrome in prematures and newborns (author's transl)]. PMID- 4216188 TI - Immunological determination of human fetal hemoglobin. PMID- 4216189 TI - Comparison of 8 different colorimetric, radiochemical and immunological procedures for the determination of iron binding capacity. PMID- 4216191 TI - [Immunological diagnosis of iga-paraproteins (author's transl)]. PMID- 4216192 TI - [The distribution of paraproteinaemias according to the sex and age of patients; classes, subclasses and light chain types of paraproteins (author's transl)]. PMID- 4216190 TI - [The importance of membrane phospholipids in the antigen-antibody binding in the Rh-D-system (author's transl)]. PMID- 4216193 TI - [Detection of several different nuclease activities in human cerebrospinal fluid (author's transl)]. PMID- 4216194 TI - [An optimized automatic method for the quantitative immunological determination of antigens and antibodies (author's transl)]. PMID- 4216195 TI - [A sphingolipidosis with the accumulation of neutral glycosphingolipids, AO2(GM3) and A1(GM2)-ganglioside (author's transl)]. PMID- 4216196 TI - Experience with immunological TBG quantitation in the clinic. PMID- 4216197 TI - Serum thyroxine radioimmunoassay, simplified. PMID- 4216198 TI - Comparison of different methods for the intensification of immunoprecipitates for the determination of trace proteins. PMID- 4216200 TI - A radioimmunoassay for erythropoietin. PMID- 4216199 TI - Incorporation of 14C- and 3H-L-leucine into immunoglobulins of different class specifity (radial-diffusion method). PMID- 4216201 TI - Immunoglobulins of human prostatic fluid in prostatitis. PMID- 4216202 TI - Carbonic anhydrase: a new method of detection on polyacrylamide gels using conductivity measurements. PMID- 4216203 TI - Cryptosporidium agni sp.n. from lambs, and cryptosporidium bovis sp.n. from a calf, with observations on the oocyst. PMID- 4216204 TI - [Aromorphic changes in the mammalian brain]. PMID- 4216205 TI - [Bacterial DNA and its replication]. PMID- 4216206 TI - [Isoenzymes as elements of the regulatory systems of homeostasis]. PMID- 4216207 TI - [Phototaxis of microorganisms, its mechanism and relation to photosynthesis]. PMID- 4216208 TI - [Fetomaternal transfusion, rhesus immunization and prevention]. PMID- 4216209 TI - [Population dynamics in a changing environment. Experiments with model populations of Drosophila melanogaster]. PMID- 4216210 TI - [Subtotal resection of the small intestine in the newborn infant; rearing with a new fully synthetic elementary diet]. PMID- 4216211 TI - [Indications for splenectomy from the internal-hematologic viewpoint]. PMID- 4216212 TI - [Hemobilia as a cause of gastrointestinal hemorrhage]. PMID- 4216213 TI - [Effect of insulin on muscular glycogen synthetase activity in chick embryos and young chickens]. PMID- 4216214 TI - [Interaction of the associative responses in the parietal cortex to stimuli of different modalities in awake Macacus rhesus monkeys]. PMID- 4216215 TI - [Dynamics of the formation of 19S- and 7S-antibodies in guinea pigs immunized simultaneously with 2 vaccines]. PMID- 4216216 TI - [Penetration of Shigella into the epithelial cells as an important condition for the possible appearance of an infectious process]. PMID- 4216218 TI - Isolation of IgA and of a fast subfraction of IgG from human placenta extract. PMID- 4216217 TI - [Immunobiological properties of the protective brucellosis antigen]. PMID- 4216219 TI - Zinc enzymes in commercial Pronase-P. Further characterization of the heterogeneity of the proteolytic enzymes of the K-1 strain of Streptomyces griseus. PMID- 4216220 TI - Estimation of the dimensions within the "pore system" in human skeletal muscle capillaries. PMID- 4216221 TI - [Post-traumatic epilepsy (author's transl)]. PMID- 4216222 TI - [Traumatic paralysis of the external popliteal sciatic nerve]. PMID- 4216223 TI - [Alpha-1-antitrypsin deficiency]. PMID- 4216224 TI - Subacute sclerosing panencephalitis: Fab-fragments and antigens. PMID- 4216225 TI - The occurrence of vaginal diphtheroids in Papanicolaou smears. PMID- 4216226 TI - Decreased antidiuretic response to lysine-vasopressin after acute administration of glibenclamide in healthy subjects. PMID- 4216227 TI - Genealogical blood-group analyses of the Danzig quintuplets. PMID- 4216228 TI - Course of serologic incompatibility in twin fetuses. PMID- 4216229 TI - Histochemical clues to problems in glucose homeostasis. The glucogenic potential of peripheral tissues and glucose-6-phosphatase activity. PMID- 4216230 TI - [Prove of the proteolytic enzyme activity using color diafilms as substrate (author's transl)]. PMID- 4216231 TI - Cytochemical observations on the vitellogenetic oocytes of Palaemon adspersus Rathke (crust. dec.). PMID- 4216232 TI - Non-specific esterase and its involvement in the dynamism of outer body covering of trematodes, cestodes and nematodes (series I). PMID- 4216233 TI - [Comparative polarization studies of isolated glomerular and tubular basement membranes of porcine kidney]. PMID- 4216234 TI - Characterization of fluorescein isothiocyanate: synthesis and testing methods for fluorescein isothiocyanate isomeres. PMID- 4216236 TI - Histoenzymological demonstration of acid phosphatase in the gizzard of Cinnyris asiatica, Megalaima haemacephala and Upupa epops. PMID- 4216235 TI - Tetracycline-labelling as a method for detecting the bone demineralization of parathormone-treated rats. PMID- 4216238 TI - Histochemistry of hydroxysteroid dehydrogenases in the kidneys of chameleon, python and crocodile. PMID- 4216237 TI - [Enzyme histochemical study of the bovine carotid artery in relaxation and after contraction with potassium chloride (author's transl)]. PMID- 4216239 TI - Letter: Salivary IgA in periodontal disease. PMID- 4216240 TI - Plasma progesterone levels in normal and abnormal pregnancies. PMID- 4216241 TI - The significance of the glomeruli-bound anti-renal basement membrane active antibody as the pathogenetic factor of human chronic glomerulonephritis. PMID- 4216242 TI - Neurofibromatosis complicated by intracranial tumors. PMID- 4216243 TI - The diagnosis of pleuro-pulmonary lesions utilizing contrast pleurography. PMID- 4216244 TI - Immunoglobulin analysis in families of myeloma patients. PMID- 4216245 TI - Long-term conservative therapy of chronic AV block. PMID- 4216247 TI - [Safety, reactivity and effectiveness testing of live shigella flexneri vaccines in laboratory animals and children (author's transl)]. PMID- 4216246 TI - Idiopathic light chain dyscrasia--a new distinct entity? Report of a case. PMID- 4216248 TI - [Immunochemical examination of typhoid and paratyphoid vaccines prepared from envelope and O antigens (author's transl)]. PMID- 4216249 TI - [Comparison of oral and subcutaneous immunization against typhoid-paratyphoid fever (author's transl)]. PMID- 4216250 TI - [Animal and human studies on oral vaccination against typhoid and paratyphoid fever (author's transl)]. PMID- 4216251 TI - Requirements for sterility testing of oral bacterial vaccines. PMID- 4216252 TI - Self-experiments with ingestion of various bacteria. PMID- 4216253 TI - [Live shigella flexneri 2a and shigella sonnei vaccines (author's transl)]. PMID- 4216254 TI - [Laboratory safety testing of live dysentery vaccine strains (author's transl)]. PMID- 4216255 TI - Intra-uterine diagnosis of birth defects. PMID- 4216256 TI - Melanocyte-stimulating hormone and the hypothalamic hormone which inhibits its release. PMID- 4216258 TI - The effect of L-DOPA on the hypothalamic-pituitary-thyroid axis. PMID- 4216257 TI - L-DOPA and the control of prolactin secretion. PMID- 4216259 TI - Dopaminergic and cholinergic mechanisms in relation to postural tremor in the monkey and circling movements in the cat. PMID- 4216260 TI - Characterisation of macroglobulins IgM aggregates. PMID- 4216261 TI - Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. III. Entero-endocrine cells. PMID- 4216262 TI - Letter: Hyperglycemia without ketosis or hypernatremia. PMID- 4216263 TI - Fatty liver produced by hyperalimentation of rats. PMID- 4216264 TI - Chronic mesenteric arterial insufficiency caused by vascular neurofibromatosis. A case report. PMID- 4216265 TI - Immunological studies of beta galactosidase in normal human liver and in GM1 gangliosidosis. PMID- 4216266 TI - A comparison of the safety and efficiency of three intermittent intravenous therapy systems--the minibottle, the minibag and the inline burette. PMID- 4216267 TI - In vivo neutron activation analysis. Clinical potential in body composition studies. PMID- 4216268 TI - Effects of nitroglycerin on left ventricular cavitary size and cardiac performance determined by ultrasound in man. PMID- 4216271 TI - Letter: Corneal cells in penetrating keratoplasty. PMID- 4216269 TI - Biologic and clinical significance of cryoglobulins. A report of 86 cases. PMID- 4216270 TI - Development of acute erythroleukemia in B-cell immunoproliferative disorders after prolonged therapy with alkylating drugs. PMID- 4216272 TI - Role of carbonic anhydrase in urinary acidification by the toad bladder. PMID- 4216273 TI - Excretion and retention of cadmium, zinc, and mercury by rabbit kidney. PMID- 4216274 TI - Hyperalimentation as a treatment of Crohn's disease. PMID- 4216275 TI - [Paroxysmal tachycardia in Wolf-Parkinson-White syndrome in a patient with multiple thoracic injuries]. PMID- 4216276 TI - [Toxic reactions during treatment of the ovarian cancer with ThioTEPA]. PMID- 4216277 TI - [Culture diagnosis of gonorrhea in women]. PMID- 4216278 TI - [Slit-lamp examination of unfixed vitreous in sheep, pigs, dogs, apes and rabbits (author's transl)]. PMID- 4216279 TI - Serum immunoglobulin M in chronic urticaria. PMID- 4216280 TI - Intermittent positive pressure breathing in management of chronic obstructive pulmonary disease: current state of the art. PMID- 4216281 TI - [The immunosuppressive agents in rheumatology. Indications, results and problems of long-term surveillance]. PMID- 4216282 TI - The influence of electrical current on an infecting microorganism in wounds. PMID- 4216283 TI - Band keratopathy in mercury exposure. PMID- 4216284 TI - Immunofluorescent test in bullous diseases of skin and mucous membranes. PMID- 4216285 TI - [Laboratory transmission and description of the Haemogregarine Lainsonia legeri n. sp. (Lankesterellidae) parasite of Brazilian lizards]. PMID- 4216286 TI - Characterization of lac+ transductants of Streptococcus lactis. AB - A phage-mediated transducing system was used in studying certain physiological characteristics of S. lactis C2 wild type, lactose-negative mutants, and lactose positive transductants. Lac(-) mutants, obtained by acriflavine treatment of the wild type, were similar to the wild type in all characteristics tested except they lacked beta-D-phosphogalactoside galactohydrolase (beta-Pgal) and could not transport [(14)C]lactose; they also had approximately 10% of the proteolytic ability than wild-type cells. The lactose-fermenting characteristic was transduced from the wild type to Lac(-) mutants. The Lac(+) transductants obtained were similar to the wild-type parent with respect to lactose fermentation and level of beta-Pgal activity (0.186 U of protein per mg). These transductants, however, had not regained full proteolytic ability and were similar to the Lac(-) mutant in this respect. Lactic acid production of the transductants in milk was approximately two-thirds that of the wild type. Data suggest that both the lactose-fermenting and proteolytic characters are carried on extrachromasomal particles (plasmids). PMID- 4216288 TI - Microculture plaque neutralization test for California group arboviruses. AB - A microculture plaque neutralization test is described for California-group arboviruses that is as precise and quantitative as the standard test conducted in 60-mm petri dishes. It was shown that there was no significant between-panel or between-day variation in determinations and that a single pipette could be used for all serum-dilution levels within a titration without inoculum carry-over effect. The experimental protocol and statistical methods used produce 50% neutralization end points that meet the assumptions of parametric statistics. This permits the power and versatility of the analysis of variance to be exploited in testing for treatment effects in serological and immunological studies with viruses. PMID- 4216287 TI - Aspergillus flavus infection and aflatoxin production in corn: influence of trace elements. AB - Distribution of trace element levels in corn germ fractions from kernels naturally infected with Aspergillus flavus and from kernels free of the fungus demonstrated an association between the presence of A. flavus and higher levels of metals. A. flavus production of aflatoxin on various autoclaved corn media showed that ground, whole corn was an excellent substrate; similar high levels of toxin were observed on full-fat corn germ but endosperm and defatted corn germ supported reduced yields. The influence of trace elements and their availability in defatted corn germ to A. flavus-mediated aflatoxin biosynthesis were measured. Enrichment of the substrate with 5 to 10 mug of manganese, copper, cadmium, or chromium per g of germ increased toxin yields. Addition of lead or zinc (50 to 250 mug/g) also enhanced toxin accumulation. Aflatoxin elaboration was reduced by the addition of 25 mug of cadmium per g or 500 mug of copper per g of germ. PMID- 4216289 TI - Diagnosis of California (La Crosse) encephalitis by precipitin techniques: a prospective study. AB - Counterelectrophoresis (CEP) and immunodiffusion (ID) were evaluated prospectively as methods for the early and rapid laboratory diagnosis of California encephalitis (CE). CEP and ID studies were done on paired sera from 127 patients with acute central nervous system infections. After the precipitin tests were completed, conventional hemagglutination-inhibition, neutralizing, and complement fixing antibody titers were measured. The CEP system detected antibodies in 7 (41%) of 17 CE patients during their acute illness and in all 17 patients during convalescence. The ID method was less sensitive; 3 of 17 acute sera and 16 of 17 convalescent sera were ID positive. Comparative precipitin studies indicated that La Crosse virus was the infecting California group subtype in all 17 CE patients. Because CEP can be performed in 1.5 h, is at least as sensitive as hemagglutination-inhibition, neutralizing, and complement fixing tests, and can detect prospectively 41% of CE patients during their acute illness, it is recommended as a rapid diagnostic test for CE. PMID- 4216290 TI - Corynebacterial kidney disease of salmonids: growth and serological studies on the causative bacterium. AB - Comparative growth studies of 10 isolates of the Corynebacterium of salmonid kidney disease were quantified on four media. Greatest cell yield was obtained from Mueller-Hinton medium with 0.1% L-cysteine hydrochloride. Serological tests, in which rabbit antisera used against typical bacteria strains showed all to be antigenically homologous, provided a reliable method of identification. PMID- 4216291 TI - Factors that influence microbial contamination of fluids associated with hemodialysis machines. AB - Studies were conducted on the microbiological quality of fluids associated with different types of dialysis systems located in six dialysis centers and 14 homes. Included were (i) single-pass systems employing either parallel flow (Kiil or Gambro) or capillary cartridge dialyzers and (ii) recirculating single-pass and batch recirculating systems using coil dialyzers. Microbiological assays were performed on the water used to prepare dialysis fluid, the concentrated dialysate, and either pre- and postdialyzer dialysate (single-pass systems) or the dialysate contained in storage reservoirs and recirculating cannisters (recirculating systems). The levels of microbial contamination consisting of gram negative bacteria were directly related to the type of dialysis system, method of water treatment, distribution system, and in some instances, the type of dialyzer. Recirculating single-pass and batch recirculating systems consistently contained significantly higher levels of contamination than single-pass systems. These results were directly related to the design of recirculating systems which permits carbon- and nitrogen-containing waste products dialyzed from the patient to accumulate, be used as nutrients by microorganisms, and subsequently allow for 2- to 4-log increases in contamination levels during a dialysis treatment. In contrast, levels of contamination in single-pass machines were related more to the quality of the water used to prepare dialysis fluid and the adequacy of cleaning and disinfection procedures than to the design of the system. PMID- 4216292 TI - Simplified extraction procedure for serological grouping of beta-hemolytic streptococci. AB - An adaptation of the nitrous acid extraction of streptococci proved to be a reliable and practical method for the preparation of extracts for routine serological group identification. The extracts of all groups tested gave strong capillary precipitin reactions as well as reactions of double diffusion in gel. For routine grouping, extracts were prepared from the first one-half-plate subculture of the initial throat culture. The technique is simple and reliable, and it requires a minimum of technical skill, reagents, and equipment. Its use would facilitate epidemiological surveillance of group A streptococci and rapid diagnosis of streptococcal infections at a low cost. PMID- 4216293 TI - The relationship of mouse spermatozoal to mouse testicular cathepsins. PMID- 4216294 TI - Reaction of human chorionic somatomammotropin and human pituitary growth hormone with tetranitromethane at 0 degrees C. PMID- 4216295 TI - Cholesterol-7 alpha-hydroxylase of pigeon liver microsomes. PMID- 4216296 TI - Xanthine phosphoribosyltransferase from Streptococcus faecalis. Properties and specificity. PMID- 4216297 TI - Action of phospholipase A2 and phospholipase C on Escherichia coli. PMID- 4216298 TI - The P700-chlorophyll a-protein. Isolation and some characteristics of the complex in higher plants. PMID- 4216299 TI - Effect of nalidixic acid on Euglena gracilis: induced loss of chloroplast deoxyribonucleic acid. PMID- 4216300 TI - Association and dissociation of phycocyanin by small molecules. PMID- 4216301 TI - Interaction of the components of the lactose synthetase system. PMID- 4216302 TI - The activation of rabbit muscle, liver, and kidney fructose bisphosphatases by histidine and citrate. PMID- 4216303 TI - Human liver carboxylesterase. Purification and molecular properties. PMID- 4216304 TI - Alternate pathways of linolenic acid biosynthesis in growing cultures of Penicillium chrysogenum. PMID- 4216305 TI - Serum IgG levels in feto-fetal transfusion syndrome. PMID- 4216306 TI - Trial comparing D-penicillamine and gold in rheumatoid arthritis. Preliminary report. PMID- 4216307 TI - [Further research on the epidemiology of cerebrospinal meningitis. Studies of the distribution of carriers of N. meningitidis in the population of Bari in the post epidemic period (3-year period of 1966-71)]. PMID- 4216308 TI - [Studies on the distribution of N. meningitidis antibodies in the population of Bari]. PMID- 4216309 TI - Residual fraction and the inotropic state of the left ventricle. PMID- 4216310 TI - A comparison of the effects of some inotropic and chronotropic agents on isolated atria from normotensive (NTR) and spontaneously hypertensive (SHR) rats. PMID- 4216311 TI - [Isoenzyme methods in the differentiation of human and monkey blood]. PMID- 4216312 TI - [Anatomical study of rheumatic tricuspid valvulopathies. Applications to the critical study of various methods of annuloplasty]. PMID- 4216313 TI - [Reversibility of pulmonary functional changes in mitral valve diseases after surgical correction]. PMID- 4216314 TI - [Anomalies in the distribution of coronary arteries and myocardial ischemia. Apropos of 2 cases]. PMID- 4216315 TI - [Coronary atherosclerosis before the age of 40. Apropos of a series of 50 subjects who had a coronarography]. PMID- 4216316 TI - [Cardiac and peripheral vascular hemodynamic disorders in labile arterial hypertension]. PMID- 4216317 TI - [Diagnosis of aortic stenoses using echocardiography]. PMID- 4216318 TI - [Functional and anatomical repercussions of hypothalamic stimulation on the cardiovascular system. Synthesis and clinical application of experimental data]. PMID- 4216319 TI - [Photon and electron microscopy study of the rat myocardium after injection of L thyroxine (influence of myocardial fixation technic)]. PMID- 4216320 TI - [Surgically treated triatrial heart in an adult. Importance of mechanography]. PMID- 4216321 TI - [Surgical repair of septal perforation during recent infarct (7th day). Long-term result]. PMID- 4216322 TI - [Case of isolated chylopericardium. Apropos of a case in an infant, review of the literature]. PMID- 4216323 TI - [Left ventricular hemodynamics in the acute stage of myocardial infarct. I. Methods--results--classification]. PMID- 4216324 TI - [Left ventricular hemodynamics in the acute stage of myocardial infarct. II. Clinico-hemodynamic correlations--prognosis]. PMID- 4216325 TI - ["Spontaneous" angor and "pure" effor angor]. PMID- 4216327 TI - [Associated sino-auricular and auriculoventricular blocks. Anatomo-clinical study]. PMID- 4216326 TI - [Importance of auricular stimulation and pharmacodynamic tests in the diagnosis of syncopes with a normal electrocardiogram]. PMID- 4216328 TI - [The short PR--normal QRS syndrome: special form of sino-auricular block? (With an anatomical study of the conduction pathways)]. PMID- 4216329 TI - [V4R--V3R electrocardiographic terminals and auriculoventricular conduction in posterior myocardial infarct]. PMID- 4216330 TI - [2 Intraoperative tests for: pulmonary hypertension, and correction of an intracardiac repair]. PMID- 4216331 TI - [Echocardiography in aortic valve diseases]. PMID- 4216332 TI - [Experimental study on the prolonged administration of alcohol on arterial lipids, and on cardiac ultrastructure and performance]. PMID- 4216333 TI - Modulation by fumarate of a Pi-insensitive pyruvate kinase from Rhodopseudomonas capsulata. PMID- 4216334 TI - [Metabolic products of microorganisms. 136. Asposterol, an antibiotic from Aspergillus microcysticus (author's transl)]. PMID- 4216335 TI - Influence of glass microbeads on growth, activity and morphological changes of Bacillus megaterium. PMID- 4216336 TI - Flexibacter elegans and Myxococcus fulvus: aerobic Gram-negative bacteria containing menaquinones as the only isoprenoid quinones. PMID- 4216337 TI - [Substitutive parenteral hyperalimentation and severe rectocolitis. Apropos of 12 cases]. PMID- 4216338 TI - [Hemophilia A and diabetes mellitus in a 13-month-old child]. PMID- 4216339 TI - [Exploration of the hypothalamo-hypophyseal-thyroid axis in children]. PMID- 4216340 TI - Intensive treatment of the adolescent and his family. PMID- 4216341 TI - Rubella precipitin response in natural infection and in vaccination. PMID- 4216342 TI - Pinocytotic uptake and intralysosomal crystal formation of coxsackievirus A9 in monkey kidney cells. An electron microscopic autoradiographic study. PMID- 4216343 TI - The antiviral activity of some related benzo(b) thiophene derivatives. II. Anti influenza activity. PMID- 4216344 TI - [Status epilepticus in the Lennox-Gastaut syndrome. I. Clinical aspects]. PMID- 4216345 TI - [Status epilepticus of the Lennox-Gastaut syndrome. II. Electroencephalographic aspects]. PMID- 4216346 TI - Pathogenesis of lead encephalopathy. Uptake of lead and reaction of brain capillaries. PMID- 4216347 TI - Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp. PMID- 4216349 TI - Studies on the effects of insulin and acetylcholine on activation of glycogen synthase and on glycogenesis in hepatocytes. PMID- 4216350 TI - Purification of antibodies to protein hormones by affinity chromatography on divinylsulfonyl sepharose. PMID- 4216348 TI - The distribution of L-asparagine synthetase in the principal organs of several mammalian and avian species. AB - A survey was conducted of the distribution of l-asparagine synthetase and of l asparaginase in the principal organs of representative mammals and birds. Although a radiometric assay was used as a routine, several additional criteria, including enzymic and chromatographic ones, were used to verify that the product of the synthetase was l-asparagine. Recoveries of exogenous l-asparagine were assessed in the presence of a number of mouse organs and found to be about 85%. In addition, evidence is presented for the existence in mouse liver of a thermolabile activity capable of destroying l-asparagine and stimulated by high concentrations of NH(4) (+) ions. Of the organs surveyed, pancreas was generally found to synthesize l-asparagine at the most rapid rate, whereas extracts of liver catalysed the decomposition of this amide at the greatest velocity. Of the species studied, guinea pig had the highest activities of pancreatic l-asparagine synthetase and also of hepatic l-asparaginase. The pancreas of mouse and ox also were good sources of l-asparagine synthetase. PMID- 4216351 TI - D-ribulose 1, 5-diphosphate carboxylase from blue-green algae. PMID- 4216354 TI - Anti-complement effects of two anti-inflammatory agents. Niflumic and flufenamic acids. PMID- 4216355 TI - Catalytic activity and inhibition of carbonic anhydrase of rat tissues. PMID- 4216357 TI - The prosthetic treatment of hepatitis B antigen positive patients. PMID- 4216358 TI - Letter: 'The prevention of transmission of serum hepatitis in dentistry'. PMID- 4216356 TI - Drug metabolism in Gunn rats: inability to increase bilirubin glucuronidation by phenobarbital treatment. PMID- 4216359 TI - Low right ventricular endocardial potentials in chronic Chagas' disease. PMID- 4216360 TI - Gastrointestinal haemorrhage from ectopic gastric mucosa lining a jejunal diverticulum. PMID- 4216361 TI - Aspects of the structure and clinical role of the carcinoembryonic antigen (CEA) and related macromolecules with particular reference to urothelial carcinoma. PMID- 4216362 TI - Sporadic G6PD deficiency with haemolytic anaemia in two children of West European ancestry. PMID- 4216363 TI - The role of complement in endotoxin shock and disseminated intravascular coagulation: experimental observations in the dog. PMID- 4216364 TI - Purification and properties of calf liver aldose reductase. PMID- 4216365 TI - On the activation of microsomal UDPglucuronyltransferase by phospholipase A. PMID- 4216366 TI - Subunit structure and catalytic activity of pig kidney alkaline phosphatase. PMID- 4216367 TI - Presence of a gelatin-specific proteinase and its latent form in human leucocytes. PMID- 4216368 TI - [Kinetic principles of RNA synthesis. V. Inverse problem for apriori models of RNA accumulation in asynchronous cell cultures]. PMID- 4216369 TI - Binding of 63Ni to rabbit serum alpha1-macroglobulin in vivo and in vitro. PMID- 4216370 TI - Histochemical observations on the localization of some enzymes associated with digestion in four species of Brazilian nemerteans. PMID- 4216371 TI - [Ribosomes and the intensity of the fundamental biosynthetic processes in bacteria]. PMID- 4216372 TI - [Purification and properties of lactate dehydrogenase isoenzyme 1 from the rat myocardium]. PMID- 4216373 TI - Molecular weight determination of bovine carbonic anhydrase. PMID- 4216374 TI - Conformational analysis of thyrotropin releasing factor by proton magnetic resonance spectroscopy. PMID- 4216375 TI - Conformational studies on the hypothalamic thyrotropin releasing factor and related compounds by 1-H nuclear magnetic resonance spectroscopy. PMID- 4216376 TI - The determination of sequence information in homologously related proteins by mass spectrometry. PMID- 4216377 TI - Properties of ribulose diphosphate carboxylase immobilized on porous glass. PMID- 4216378 TI - studies on aminoacylase immobilized on porous ceramic carriers. PMID- 4216379 TI - [Blastomogenic effects of some azo-containing compounds on the progeny of test mice]. PMID- 4216380 TI - [Determination of 3-oxyanthranilic acid in the blood serum in the immunodiagnosis of precancerous changes in the mucous membrane of the urinary bladder]. PMID- 4216381 TI - Immunodepressive action of oncogenic virus SA7 (C8). PMID- 4216382 TI - Zinc and insulin content in pancreatic islets of rats after administration of hypoglycemic sulfonamides. PMID- 4216383 TI - The use of anti-immunoglobulin for the immunoprecipitation of labeled proteins from tissue homogenates. PMID- 4216384 TI - A sensitive and specific assay for cystathionine: cystathionine content of several plant tissues. PMID- 4216385 TI - Proceedings: Structure-activity relationships in the sulphonamide-carbonic anhydrase systems. PMID- 4216386 TI - The pharmacokinetics of (14C)-edrophonium in normal wistar rats and homozygous Gunn rats with ligated renal pedicles. AB - 1 The distribution kinetics of [(14)C]-edrophonium were studied in both normal Wistar and homozygous Gunn rats with ligated renal pedicles.2 After intravenous injection the plasma concentration-time curve of [(14)C]-edrophonium was adequately fitted by a triexponential function in both species of rat and interpreted in terms of a three compartment model.3 The influence of the route of administration (i.e., systemic venous versus hepatic portal) of [(14)C] edrophonium on its concentration in plasma was studied in normal Wistar rats with ligated renal pedicles. There was a marked difference in the area under the plasma concentration-time curve depending on the route of administration.4 The parameters of the model were determined and compared.5 The value of the metabolism rate constant was approximately the same in both species of rat. This suggests that the rate of conjugation of [(14)C]-edrophonium is unaltered in the homozygous Gunn rat despite the genetic lesion in UDP-glucuronyltransferase. PMID- 4216387 TI - Sticky eye in the newborn. PMID- 4216388 TI - Lacticacidosis, ketoacidosis, and hyperalaninaemia in a phenformintreated diabetic patient. PMID- 4216391 TI - Letter: Pseudomonas septicaemia following superficial colonization. PMID- 4216390 TI - Immunodiagnosis of snake bite. AB - Management of a patient with snake bite is influenced by the nature of the offending snake. Species diagnosis based on the patient's history and physical signs is often unreliable and the possibility of making a species diagnosis by immunological means has therefore been investigated. Wound aspirates, blister fluids, sera, and urine samples from patients with snake bite were examined for the presence of species-specific venoms using immunodiffusion. A positive species diagnosis was made in 40 out of 101 patients. Immunodiagnosis was especially successful in patients bitten by the puff adder, Bitis arietans, and the African spitting cobra, Naja nigricollis. A higher success rate could probably be achieved using more specific antisera and more sensitive assay techniques. PMID- 4216389 TI - Studies on whole-body potassium in non-ketoacidotic diabetics before and after treatment. AB - Serial measurements of whole-body potassium were carried out in 28 diabetic patients, in 23 of whom diabetes had only recently been diagnosed. Eleven patients were treated with insulin, 12 with oral hypoglycaemic agents, and the rest were already on oral hypoglycaemic agents and had developed poor diabetic control; four of these required insulin. Whole-body potassium was measured before treatment was begun (or altered) and again one and six weeks later. Whole-body potassium (ratio of observed to expected) was initially reduced in most of the patients requiring insulin. After control of diabetes whole-body potassium increased significantly in the three groups. The increase in whole-body potassium in the individual patients varied over a wide range, and in patients who were treated with insulin it was often of a similar magnitude to that observed in patients in diabetic ketoacidosis. PMID- 4216392 TI - [Our clinical experience with penicillin V in doses of 1,000,000 U.I. in ORL]. PMID- 4216393 TI - Active insoluble prostatic phosphatase cocrosslinked with bovine serum albumin by glutaraldehyde. PMID- 4216394 TI - Ovarian cancer. PMID- 4216395 TI - Special report: chemical carcinogenesis. PMID- 4216396 TI - [Alexander Brunschwig (1901-1969)]. PMID- 4216397 TI - Resection of head of pancreas and duodenum for carcinoma--pancreatoduodenectomy. PMID- 4216398 TI - Photosynthesis and nitrogenase activity in the blue-green alga Gloeocapsa. PMID- 4216400 TI - Plaque formation in Bacillus subtilis, and growth inhibition of Bacillus subtilis and Sarcina sp., induced by Schizophyllum commune. PMID- 4216399 TI - Action of chlorpromazine on spore-forming Bacillus species. PMID- 4216401 TI - [Primary resistance to INH, PAS and STM. Significance of individual mycobacterial strains for newly diagnosed cases of pulmonary tuberculosis in the middle Bohemia region in 1967 and 1972 (author's transl)]. PMID- 4216402 TI - An ultrastructural study of the juxtaglomerular apparatus in the toad, bufo bufo. PMID- 4216403 TI - A system for mapping DNA sequences in the chromosomes of Drosophila melanogaster. PMID- 4216404 TI - Isolation and characterization of polysomes from Chironomus salivary glands. PMID- 4216405 TI - [Moraxellae and bacteriological diagnosis of gonorrhea]. PMID- 4216407 TI - A comparison of African and European serum levels of immunoglobulin E. AB - The mean level of serum IgE in Nigerian blood donors is significantly higher than those in expatriates living in Nigeria and in Swiss blood donors. The examination of serum IgE levels (by the radioactive single radial diffusion technique) in Nigerian patients with different diseases, in asthmatic children with matched controls in Ghana, and in subjects from malarious and non-malarious areas of Tanzania indicates that high IgE levels in Africans may not be due to malaria, vesical schistosomiasis, or onchocerciasis infections. A marked difference, however, was found between African subjects with positive and negative findings of stool parasites; they had higher and lower mean levels of serum IgE, respectively. It seems that, in an African population where the serum IgE levels are raised for other reasons, a rise in IgE in association with allergic conditions such as asthma may not be apparent. PMID- 4216406 TI - N-oxidation and demethylation of N,N-dimethylaniline by rabbit liver and lung microsomes. Effects of age and metals. PMID- 4216408 TI - Immunopathology of malaria. AB - Antibodies with different spectra of reactivity are produced during malarial infections and marked changes in IgG and IgM levels occur. In addition malaria elicits serological changes that are usually associated with connective tissue disease. The excessive anaemia associated with malaria may, in part, be an autoimmune phenomenon. Transient nephritis accompanies many plasmodial infections but chronic malarial nephrotic syndrome is specifically associated with quartan malaria. Malarial infection leads to splenomegaly, the most extreme form of which is idiopathic tropical splenomegaly, which probably represents an aberrant immune response to the infection. Malaria can affect the humoral immune response to unrelated antigens and infectious agents. This may be relevant to the etiology of Burkitt's lymphoma. During pregnancy there is some loss of acquired immunity to P. falciparum and the placenta appears to be an immunologically privileged site for the multiplication of this parasite. PMID- 4216410 TI - The indirect haemagglutination test for malaria and its application to epidemiological surveillance. AB - Recent studies with the indirect haemagglutination test for malaria are reviewed. Aspects of methodology, reproducibility, specificity, and sensitivity are discussed. A procedure is presented for application in the field, which indicates some progress towards developing a simple field method for the epidemiological surveillance of malaria. PMID- 4216409 TI - Other pathological processes in malaria. AB - Research since the World War II has confirmed that, apart from the production of haemozoin from haemoglobin, most of the pathological processes in the evolution of malaria are nonspecific. A few of these nonspecific host reactions are discussed, including the production of inflammatory stasis in certain areas (including the brain) where the vascular endothelium is normally highly impermeable to heavy molecules. This production of stasis is regarded as the basic phenomenon in local obstruction to blood flow. So-called "plugging" of small vessels with "sticky" infected erythrocytes is discussed in relation to stasis and to deep intravascular schizogony. Nonspecific vasomotor effects including shock and renal and hepatic failure are also discussed. Intravascular coagulation is not regarded as a potentially important host response despite demonstrable consumption coagulopathy. The disease malaria is regarded as an example of a chain reaction of physiological-pathological responses in the host, which in the early stages are reversible. PMID- 4216411 TI - Prospects for vaccination against malaria in man. AB - Rodents have been successfully protected against a challenge of viable Plasmodium berghei by employing as vaccine: (1) the irradiated blood stages of the same parasite, or (2) the water-insoluble fraction of the blood stages, or (3) irradiated sporozoites; all these vaccines were shown to be stage-specific. A method is outlined for testing in the field, in the absence of any risks, the efficacy of analogous vaccines against falciparum malaria in man. It is emphasized that: (1) the efficacy of the vaccines can be tested in no model but only against P. falciparum in man; (2) the protection should be measured in terms of (a) prevention of morbidity, and (b) prevention of mortality; and (3) research must be intensified in order to meet, as needed, the requirements of mass production of merozoites and/or sporozoites, and to find ways to increase the human immune response to a higher level of protection against P. falciparum. PMID- 4216412 TI - [Effects of denervation on the activity of glycolytic enzymes in striated muscles of Rana temporaria]. PMID- 4216413 TI - [Enzyme-substrate behavior. Introduction of the concept of enzymatic stability in the case of beta-lactamases]. PMID- 4216414 TI - [Increase in progesterone and spike of estrogen-immunoreactive compounds in the plasma of sexually immature rats]. PMID- 4216416 TI - [Role of the dermis in differentiation of the nasolacrimal duct in Discoglossus pictus (anourous amphibian)]. PMID- 4216415 TI - [Retinoic acid and biosynthesis of testicular delta 4-3 hydroxysteroids in the vitamin A-deficient Wistar rat]. PMID- 4216417 TI - [Induction of estrogen synthesis by androgens]. PMID- 4216419 TI - [Active transport: modulation of output flow as a function of energetic coupling]. PMID- 4216418 TI - [Ionic currents through excitable artificial membranes according to the theory of absolute reaction speeds]. PMID- 4216421 TI - [Interactions between external and endogenous factors in the regulation of estrus rhythm in rats]. PMID- 4216420 TI - [Development of polyploidy in experimental deciduoma in the female rat in unilateral pregnancy: cytophotometric study]. PMID- 4216422 TI - [Demonstration of a fetal form of hepatic uridine kinase in the rat]. PMID- 4216424 TI - [Glucose-6-phosphate dehydrogenase and pentose pathway in the hibernating dormouse Glis-glis (L.)]. PMID- 4216423 TI - [Detection of viral antigens in human leukemias]. PMID- 4216425 TI - [Persistance of axons during the final stages of flight muscles involution in Acheta domestica]. PMID- 4216427 TI - [Synergic effects of acoustic stimulations and of a stress situation on overall demonstrable behavior]. PMID- 4216426 TI - [Myocardial phospholipids of rats having ingested for 7 months either a canbra or peanut oil diet]. PMID- 4216428 TI - [Development of gonads transplanted into the limb. Axolotl. Effect of castration of the host animals]. PMID- 4216429 TI - [Interspecific nucleocytoplasmic hybridization produced by nuclear graft between the species Ambystoma mexicanum Shaw and Ambystoma dumerilii, Duges Urodela Amphibians]. PMID- 4216430 TI - [Protective action of pralidoxime against the teratogenic effects of parathion on the axial skeleton of the quail embryo]. PMID- 4216431 TI - [T4 bacteriophage irradiation in a 1 million volt microscopemprelimnary results]. PMID- 4216432 TI - [Composition of gases emitted by Clostridium histolyticum cultivated on sodium thioglycolate media in a vaccuum, after alkalinisation of the medium at the end of culturing]. PMID- 4216433 TI - [Bacteriophages contaminating preparations of calf serum for tissue culture]. PMID- 4216434 TI - [Sialic acid level of epididymal spermatozoa: indirect in vitro evaluation in rats]. PMID- 4216435 TI - [Variations in levels of corticosteroid synthesis during embryonic development in rabbits and mice]. PMID- 4216436 TI - Extrinsic error in amniotic bilirubin determination for the prediction of antenatal hemolytic disease. PMID- 4216437 TI - Studies of malformation syndromes in man. XXVII. The N syndrome, a "new" multiple congenital anomaly-mental retardation syndrome. PMID- 4216438 TI - Prenatal diagnosis: detailed chromosomal analysis in 500 cases. PMID- 4216439 TI - Techniques in megavoltage radiotherapy. No. 5. Carcinoma of the bladder. PMID- 4216440 TI - Diverticulosis of the Fallopian tubes. PMID- 4216441 TI - Free radical production by metallic copper. PMID- 4216442 TI - Serum protein components in human endometrium. PMID- 4216443 TI - Bilateral vas ligation: sperm antibodies. PMID- 4216444 TI - Effects of postovulatory norethindrone and estrogens on the plasma levels of estrogen and progesterone in rhesus monkeys. PMID- 4216445 TI - Effect of oxytetracycline on the growth curve of Rickettsia prowazekii in the organism of the body louse (Pediculus humanus corporis L.) and Ornithodoros moubata tick (Murray). PMID- 4216446 TI - [Scintigraphic follow-up in the early diagnosis of spondylarthritis ankylopoitica]. PMID- 4216447 TI - [Transhepatic endless-drainage for the prevention of repeated surgery of the biliary tract]. PMID- 4216448 TI - RNA synthesis in Drosophila melanogaster polytene chromosomes. Indications of simultaneous dosage compensation and dosage effect in X chromosomes. PMID- 4216450 TI - [Rehabilitation in geriatrics]. PMID- 4216449 TI - [Formation of an antigenic spectrum in nerve tissue culture]. PMID- 4216451 TI - [Concentration of immunoglobulins in the serum in relation to intrahepatic reactions of mesenchymal cells]. PMID- 4216453 TI - Polyol metabolism in monkey-kidney epithelial-cell cultures. Sorbitol synthesis. PMID- 4216452 TI - Neurophysin in rat posterior pituitary after ether anesthesia: disc electrophoresis, immunodiffusion and histology of hypothalamic nuclei. PMID- 4216454 TI - Primary structure of kappa light chain from a human myeloma protein. PMID- 4216456 TI - Introduction to the discussion on characteristics of installations for radiotherapy with fast neutrons and other types of high-LET radiation. PMID- 4216455 TI - Control of ornithine carbamoyltransferase activityby arginase in Bacillus subtilis. PMID- 4216457 TI - Characteristics of 252Cf neutron sources used for radiotherapy. PMID- 4216458 TI - Radiobiology with heavy charged particles directed at radiotherapy. PMID- 4216459 TI - Negative pions in radiotherapy: a brief review. PMID- 4216460 TI - Review of RBE values of 15 MeV neutrons for effects on normal tissues. PMID- 4216461 TI - The RBE of cyclotron neutrons for effects on normal tissues. PMID- 4216462 TI - Repair and repopulation in mouse skin during fractionated neutron and x irradiation. PMID- 4216464 TI - A D-T neutron source with rotating target for radiotherapeutic applications. PMID- 4216463 TI - Production of 14 MeV neutrons by a mixed deuterium-tritium beam. PMID- 4216465 TI - Neutron-therapy facility at the Radiotherapy Department of the University Hospital, Hamburg-Eppendorf. PMID- 4216466 TI - The "Hiletron" neutron generator at Manchester. PMID- 4216467 TI - Recirculating gas target source for neutron cancer therapy. PMID- 4216469 TI - The MANTA neutron-therapy facility at the Naval Research Laboratory. PMID- 4216468 TI - 9-Be(d,n)10-B reaction for radiotherapeutic applications at the cyclotron in Rossendorf. PMID- 4216470 TI - Fast neutron beams from the MSKCC cyclotron. PMID- 4216471 TI - The 7-Li(p,n)7-Be reaction as a useful source of fast neutrons for therapy. PMID- 4216472 TI - Preliminary study of the neutron beam from 70 MeV deuterons on thick beryllium at the University of Maryland cyclotron. PMID- 4216473 TI - A fast neutron beam facility at the cyclotron of the University of Louvain. PMID- 4216474 TI - Neutron therapy application at the Heidelberg cyclotron facility. PMID- 4216475 TI - The fast neutron beam radiotherapy installation at the TAMVEC cyclotron. PMID- 4216476 TI - A medical cyclotron program in the National Institute of Radiological Sciences (NIRS), Japan. PMID- 4216477 TI - The University of Washington fast neutron beam therapy facility. PMID- 4216478 TI - Stanford University Hospital negative pi-meson beam radiotherapy program. PMID- 4216479 TI - Possible pion sources for radiotherapy. PMID- 4216480 TI - The negative pi-meson biomedical facility at TRIUMF. PMID- 4216481 TI - Characteristics of tumour responses to different radiations and the relative biological effectiveness of fast neutrons. PMID- 4216482 TI - On the relative importance of hypoxic cells for the radiotherapy of human tumours. PMID- 4216483 TI - Comparison of RBE values of 15 MeV neutrons for damage to an experimental tumour and some normal tissues. PMID- 4216484 TI - RBE values of 15 MeV neutrons applied at low dose rates. PMID- 4216485 TI - Dosimetry of 9be (d, n) 10b neutrons for radiotherapeutic applications at the cyclotron in Rossendorf. PMID- 4216487 TI - Neutron dosimetry for the MANTA facility at NRL. PMID- 4216486 TI - The fast neutron beams from the TAMVEC cyclotron. PMID- 4216488 TI - Fast neutron beam dosimetry: comparison of the ion chamber and proportional counter approaches. PMID- 4216489 TI - Energy distribution and depth doses of D-T neutrons in a tissue-equivalent phantom by activation threshold detectors. PMID- 4216491 TI - Neutron dosimetry system for routine treatment control. PMID- 4216490 TI - Dosimetry of D-T neutrons for radiotherapeutic applications at Rijswijk. PMID- 4216492 TI - Neutron dosimetry in Manchester. PMID- 4216493 TI - Neutron energy spectra in a phantom for the Hamburg and Heidelberg therapy units. PMID- 4216494 TI - Dosimetry of fast neutrons for radiotherapy at the DKFZ cyclotron in Heidelberg. PMID- 4216495 TI - Dosimetry for D-T neutrons at Glasgow. PMID- 4216496 TI - Preliminary dose measurements in the fast neutron beam at the cyclotron of the University of Louvain. PMID- 4216497 TI - Neutron dose distributions and RBE. PMID- 4216498 TI - Collimation of a 14 MeV neutron beam. PMID- 4216499 TI - Calculation of depth dose and beam profile for the fast neutron beam produced by the Heidelberg cyclotron. PMID- 4216500 TI - Contribution of patient scatter to 15 MeV neutron beam penumbra. PMID- 4216502 TI - Experimental studies in the collimation of 14-8 MeV neutrons. PMID- 4216501 TI - Some aspects in neutron shielding and collimation. PMID- 4216503 TI - Dosimetry for neutron radiotherapy. PMID- 4216504 TI - Depth dose characteristics and beam profile properties of cyclotron-produced neutron beams. PMID- 4216505 TI - Developments in achieving optimum beam profiles for 15 MeV neutron beams. PMID- 4216507 TI - [Problems in percutaneous administration of drugs. 2. On the mucous membrane, especially on mucouse membrance of the eye]. PMID- 4216506 TI - Low dose tolerance preventing tumor immunity. PMID- 4216508 TI - [Fate of experimentally administered drugs. 2. Study of absorption, distribution and excretion of drugs by whole body autoradiography]. PMID- 4216509 TI - [Fate of experimentally administered drugs. 3. Several problems concerning animal experimentals]. PMID- 4216510 TI - [Fate of experimentally administered drugs. 4. Drug absorption and species specificity]. PMID- 4216511 TI - Protein synthesis of monkey lung subcellular fractions after exposure to silica in vivo. PMID- 4216512 TI - Endosymbiotic microorganisms in Cletus signatus Walker (Coreidae: Heteroptera). PMID- 4216513 TI - Medicaid coverage of abortions in New York City: costs and benefits. PMID- 4216514 TI - The release of proteins and 5S RNA during the unfolding of Escherichia coli ribosomes. PMID- 4216515 TI - Purification and properties of tyrosinase inhibitor from mushroom. PMID- 4216517 TI - [Nursing aspects in intravenous feeding]. PMID- 4216516 TI - Delta pH and membrane potential in bacterial chromatophores. PMID- 4216518 TI - Medicaid in Delaware. PMID- 4216519 TI - [Liver biopsy studies in long-term therapy of psoriasis using methotrexate]. PMID- 4216520 TI - Ontogenesis of Ca++ and Mg++ contents of embryonic chick heart. PMID- 4216521 TI - Failure of synthetic TRF to elicit metamorphosis in frog tadpoles or red-spotted newts. PMID- 4216522 TI - Some observations on the study of the genetic control of meiosis in Drosophila melanogaster. PMID- 4216524 TI - Long term success with homograft reconstruction of the aorta for the cure of aneurysm. PMID- 4216523 TI - Mechanisms of chromosomal and gene inactivation in Drosophila. PMID- 4216525 TI - The measurement of renal function in children: a review. PMID- 4216526 TI - [Molecular medicine as illustrated by some maladies of protein templates (author's transl)]. PMID- 4216527 TI - Autoradiographic and cytophotometric investigations on blast cells from acute leukaemia. PMID- 4216528 TI - Phytohemagglutinin-stimulated rat lymphocytes and spleen-colony formation. PMID- 4216529 TI - The influence of prostaglandins E1 and E2 on platelet aggregation in mammals. PMID- 4216530 TI - [Evaluation of a fully automatic platelet counting technique on whole blood (author's transl)]. PMID- 4216531 TI - [Quantitative evaluation of G, A and M immunoglobulins in human sera (author's transl)]. PMID- 4216532 TI - [Spontaneous splenic haematoma in haemophilia. Report of a case and review of the literature (author's transl)]. PMID- 4216534 TI - Biological abnormalities in erythroblasts and erythrocytes of acquired idiopathic dyserythropoietic anemia. PMID- 4216533 TI - [Acquired von Willebrand's syndrome during collagen disorder (author's transl)]. PMID- 4216536 TI - [Intravenous hyperalimentation in the surgical patient]. PMID- 4216535 TI - [Total intravenous feeding in infants]. PMID- 4216537 TI - [Intravenous hyperalimentation in pediatric surgery]. PMID- 4216538 TI - [Editorial: Fructose as a substitute for glucose in intravenous feeding]. PMID- 4216539 TI - On the alkaloids of Fumaria parviflora Lam. PMID- 4216540 TI - On the diagnostical value of the white phenomenon's reaction and Black's reaction in malignant diseases. PMID- 4216541 TI - Study on the antimycotic action of some essential oils obtained from local and introduced plants species. PMID- 4216543 TI - Changes in foetal electrocardiograms in oxytocin stimulated birth. PMID- 4216542 TI - Gaseous and acid-base changes in patients with cirrhosis hepatis in 100% oxygen respiration. PMID- 4216544 TI - Uroinfection and antibiotic activity by calculous pyelonephritis. PMID- 4216545 TI - Changes in the concentrations of the water soluble proteins and the activities of the lactic dehydrogenase, glutamic oxalacetic and glutamic-peruvic transaminases in m. gastrocnemius of a rat at various stages after crushing the innervating nerve (reinnervation). PMID- 4216546 TI - Differences in the histomorphologic and histochemical structure of the so called "progressive" and "stationary" pterygium. PMID- 4216547 TI - Electronomicroscopic morphometric changes the liver cell of rats following administration of alcohol and alcohol-reserpin. PMID- 4216548 TI - The effect of the constant magnetic field upon the growth and development of Tr vaginalis. PMID- 4216549 TI - The influence of the ionised air upon the development of Trichomonas vaginalis in cultures. PMID- 4216550 TI - On the antimycotic effect of the Mericleri salt. PMID- 4216551 TI - Studies on the incidence of some infrabacterial pneumonias (viral-ricketsial and mycoplasmic) in Plovdiv during the period 1969-1971. PMID- 4216552 TI - Comparison of the indices of the bromsulphalein test, the serum cholinesterase and the galactose test by hepatic cirrhosis. PMID- 4216553 TI - On the diagnostical value of the indocyane clearance in chronic deseases of the liver. PMID- 4216554 TI - Types of vaginal cytosmears in late pregnancy and their prognostic value. PMID- 4216555 TI - Preparing of labelled with 113m In ferric hydroxyde for scintigraphic examination of the lung. PMID- 4216556 TI - A study upon the incidence and typal composition of the fungi Candida sp. in cases of mixed invasion with Tr. vaginalis by vaginal deseases. PMID- 4216557 TI - In support of the principle of metorysis. PMID- 4216558 TI - [Increased capillary permeability caused by bacterial pyrogenic substances]. PMID- 4216559 TI - Gastro-intestinal absorption and toxicology: ingesta-exchange and simulated-meal techniques. PMID- 4216560 TI - [Pathogenesis of epileptic seizures in patients with cerebral arteriovenous angioma. The role of cerebral ischemia (author's transl)]. PMID- 4216561 TI - Syndromes of Sturge-Weber and Klippel-Weber in the same patient. PMID- 4216562 TI - The stature of offspring and the assortative mating of parents. PMID- 4216563 TI - A relationship between plasma cholesterol level, latitude, and the Rhesus blood group system. PMID- 4216564 TI - Metric trends of the anterior teeth in African monkeys. PMID- 4216565 TI - Molecular mechanism of glucose-6-phosphate dehydrogenase deficiency. PMID- 4216566 TI - Is health care a right? Negative response. PMID- 4216567 TI - Immunological studies in tropical eosinophilia. PMID- 4216568 TI - Histoplasmin sensitivity survey. PMID- 4216569 TI - Circulatory immunoglobulin levels after an oral killed typhoid vaccination. PMID- 4216570 TI - Degree of acetonaemia following epinephrine infusion to determine biochemical characterization of diabetes mellitus. PMID- 4216572 TI - Bacteriophage typing of hospital strains of Pseudomonas aeruginosa. PMID- 4216571 TI - Factors influencing natural immunization in diphtheria in urban and rural communities in West Bengal. PMID- 4216573 TI - Evaluation of gel diffusion precipitin test for amoebiasis. PMID- 4216574 TI - Listeria meningitis in Delhi (a pilot study). PMID- 4216575 TI - Reduction of drug resistance of mycobacterium tuberculosis after treatment with hamycin. PMID- 4216577 TI - Australia antigen in cirrhosis of childhood. PMID- 4216576 TI - Studies on freeze dried smallpox vaccine as a source of antigen in the precipitation-in-gel test. PMID- 4216578 TI - Bacterial response to combination of tetracycline and gentamicin. PMID- 4216579 TI - Prevalence of Brucella agglutinins in sera received for serological test for syphilis and Widal test. PMID- 4216580 TI - Diphtheria carriers among school chidren in Poona. PMID- 4216581 TI - Letter: Raised intra cranial tension due to rapid brain growth. PMID- 4216582 TI - Screening for PKU of preschool children and newborn infants in Hyderabad. PMID- 4216583 TI - Blood free alpha amino nitrogen in hypoproteinemia. PMID- 4216584 TI - [Meningococcal meningitis in Sao Paulo, Brazil]. PMID- 4216585 TI - [Lipid A antibody titers in pyelonephritis and other gram-negative infections (author's transl)]. PMID- 4216587 TI - Metabolic problems during mechanical ventilation of newborn infants. PMID- 4216586 TI - [Blood and tissue concentrations as parameters for quantitative chemotherapy (author's transl)]. PMID- 4216588 TI - Increased response of anoxic Bacillus megaterium spores to radiation at high dose rates. PMID- 4216589 TI - Renovascular hypertension in neurofibromatosis. PMID- 4216590 TI - Diagnosis of rubella virus infection. II. The usefulness of sucrose density gradient centrifugation and indirect fluorescent antibody staining to demonstrate rubella IgG antibodies. PMID- 4216591 TI - Immunological identity between seminal plasma ribonuclease (BS-1) and seminal vesicle ribonuclease (SV-1). PMID- 4216592 TI - Proceedings: Recent researches on sphingolipidoses. PMID- 4216594 TI - [Letter: Cafe-au-lait spots and Recklinghausen's disease]. PMID- 4216593 TI - Synthesis of bacteriophage phi DNA in toluenized preparations of Bacillus subtilis infected cells. PMID- 4216595 TI - [Atypical Mycobacteria]. PMID- 4216596 TI - Australia antigen in viral hepatitis and hepatic cirrhosis. PMID- 4216597 TI - An angiomatous malformation of brain with unusual clinical manifestations. PMID- 4216599 TI - Culture of specimens other than sputum for Mycobacteria. AB - A comparison has been made of Lowenstein-Jensen medium, with or without added pyruvate, 7H11 oleic acid-albumin agar slopes made selective by the addition of antibiotics, and selective Kirchner medium in the isolation of tubercle bacilli from specimens other than sputum. A combination of a standard mild preliminary treatment with sulphuric acid and selective medium reduced the contamination rate to 0.1%. Neither acid treatment nor antibiotics appeared to reduce the isolation rate. An effective procedure is to treat all specimens (except cerebrospinal fluid) with acid and culture on two Lowenstein-Jensen slopes (one with pyruvate), a 7H11 selective slope, and in two bottles of selective Kirchner medium. PMID- 4216598 TI - Folates in human serum. AB - Constituent serum folates have been shown to be altered and in some cases raised in diseases in which total folate levels are known to be frequently decreased. Absorption experiments showed that orally administered folate analogues affect the folate pool in different ways. The stability of the 10-formyltetrahydrofolate level in normal subjects is demonstrated. PMID- 4216601 TI - Sterilization of the biological safety cabinet. AB - Test strips comprising B subtilis spores or M phlei cells dried on aluminium foil (some serum-coated) were used to test sterilizing processes currently advised for safety cabinets. Exposure to formalin from a bowl, boiling excess formalin with the fan running, and ultraviolet radiation were all found to be unreliable, as was glutaraldehyde. Vaporization of 2 ml of formalin per 0.028 m(3) followed by exposure for 18 hours at ambient temperatures was 100% successful, and the depolymerization of paraformaldehyde tablets with a hair drier was a simple, very effective alternative method. PMID- 4216600 TI - Comparison of the titres of ASO, anti-DNase B, and antibodies against the group polysaccharide of group A streptococci in children with streptococcal infections. AB - Antibodies against the group polysaccharide of group A streptococci were estimated by means of a haemagglutination reaction. In this reaction human erythrocytes of blood group O were sensitized with polysaccharide esterified with myristoylchloride. The optimal conditions of the reactions were determined by varying the ester group content in the antigen and the amount of ester used for sensitization. The specificity of the reaction could be established by reacting sensitized erythrocytes with homologous and heterologous sera and by absorption experiments. Antistreptococcal group A polysaccharide titres (ASPAT) and antibody levels to streptolysine O and DNase-B were compared in a group of 52 children with proved streptococcal infection and in 52 age- and season-matched controls. Antibody levels were significantly higher in the patient group than in the controls. In the ASPAT there was clearly less overlap between patients and controls than in both other reactions. In the patient group the ASO titres were raised above normal in 27 cases (51.9%), anti-DNase-B titres in 18 (34.6%), and ASPAT in 40 (76.9%). Taken together the three reactions gave a positive score in 51 cases (98.1%) in the patient group against 17 cases (32.7%) in the controls. A positive antibody response is usually defined as a rise of two dilution increments between the acute and convalescent sera. According to this definition the ASPAT showed a response in 42%, ASO and/or DNase-B in 42%, and the three reactions taken together in 68% of paired sera from patients. It is believed the ASPAT will prove a welcome addition to the diagnostic outfit when the presence of streptococcal infection in children is considered. PMID- 4216602 TI - Proceedings: The freeze-etching approach to the study of islet pathophysiology in diabetes. PMID- 4216603 TI - A simplified method for the detection of rubella-specific IgM employing sucrose density fractionation and 2-mercaptoethanol. AB - A simplified method for the detection of rubella-specific IgM in sera was developed involving HAI tests on only one fraction from a sucrose density gradient with and without treatment with 2-mercaptoethanol (2 ME). Slight trailing of IgG into the IgM fraction was shown to occur in patients with high titres of both IgG and IgM, but this could be detected by the 2ME treatment and did not affect the results.By this test, rubella-specific IgM was found in all of 54 patients with a rash and a rise of rubella HAI antibodies. When the antigen and serum were incubated for 1 hr. before adding the RBC, specific IgM was found in all 51 sera taken between 5 and 40 days after onset, and in about half the sera taken between 42 and 77 days, but in none of 16 people known to have possessed rubella antibodies at least a year previously. When antigen and serum were incubated for 18 hr. before adding the RBC, specific IgM was found in all of 21 sera taken between 2 and 49 days after onset, and in 6 of 11 sera taken between 50 and 117 days, but not in 9 people known to have possessed rubella antibodies at least a year before. The method has been found to be very useful in detecting recent rubella among patients in early pregnancy. PMID- 4216605 TI - The survival and growth of Bacillus cereus in boiled and fried rice in relation to outbreaks of food poisoning. AB - A number of outbreaks of food poisoning attributed to Bacillus cereus have been reported recently and all have been associated with cooked rice usually from Chinese restaurants and ;take-away' shops.Tests were made to assess the heat resistance of B. cereus spores in aqueous suspension, the growth of the organism in boiled rice stored at temperatures in the range 4-55 degrees C., and the effect of cooking and storage on the growth of the organism in boiled and fried rice. The spores of B. cereus survived cooking and were capable of germination and outgrowth. The optimum temperature for growth in boiled rice was between 30 degrees and 37 degrees C. and growth also occurred during storage at 15 degrees and 43 degrees C.To prevent further outbreaks it is suggested that rice should be boiled in smaller quantities on several occasions during the day, thereby reducing the storage time before frying. After boiling the rice should either be kept hot (> 63 degrees C.) or cooled quickly and transferred to a refrigerator within 2 hr. of cooking. Boiled or fried rice must not be stored under warm conditions especially in the range 15-50 degrees C. PMID- 4216607 TI - Biology and pathogenicity of the microsporidian Perezia hyperae sp. n., a pathogen of the alfalfa weevil, Hypera postica. PMID- 4216604 TI - Mycoplasmacidal activity of bovine milk for T-mycoplasmas. AB - Normal bovine milk and whey was mycoplasmacidal for 6 of the 13 strains of bovine T-mycoplasmas examined. The in vitro assay used also demonstrated no killing of the human, canine and simian T-mycoplasma strains after 4 hr. incubation. However, there appeared to be some cow-to-cow variation in possession of this activity, and following E. coli endotoxin stimulation of the mammary gland the activity was considerably reduced.Whey from three normal cows was fractionated on a Bio-Gel A 1.5 m. column and the mycoplasmacidal activity of the resulting five peaks assayed. Only the second peak, peak B, contained activity and was characterized as the only peak containing bovine IgA. The active component in whey, however, was found to be heat stable at 60 degrees C. for 60 minutes and to pass through a dialysis membrane. This is inconsistent with it being immunoglobulin. PMID- 4216608 TI - Shell mats associated with microsporida in Biomphalaria glabrata: genetic studies. PMID- 4216606 TI - Clinical evaluation of practolol in the treatment of angina pectoris. PMID- 4216609 TI - The antibacterial efficiencies of ovine IgA, IgM, and IgG. PMID- 4216610 TI - Treatment of gonorrhea with cefazolin plus probenecid. PMID- 4216611 TI - [Rapid detection of Salmonella: Evaluation of requirements for enrichment serology procedure and its clinical application]. PMID- 4216613 TI - [In memory of Prof. Bunya Nakamura]. PMID- 4216612 TI - [Case of terminal ileitis due to Yersinia pseudotuberculosis]. PMID- 4216614 TI - [Ligamentum flavum ossification simulating spinal cord tumor (author's transl)]. PMID- 4216616 TI - Letter: ATP content in erythrocytes of Plasmodium knowlesi-infected monkeys. PMID- 4216615 TI - Guidelines for total parenteral nutrition. PMID- 4216617 TI - Proceedings: Inhibition of hypothalamic unit activity by iontophoretically applied luteinizing hormone releasing factor and thyrotrophin releasing factor. PMID- 4216618 TI - Calcitonin given intragastrally and resistance to histamine-induced peptic ulcer in guinea-pigs. PMID- 4216619 TI - Proceedings: The relationship between prolactin and gonadotrophins: effects of clomiphene administration in normal men. PMID- 4216620 TI - Proceedings: Effect on prolactin secretion of thyrotrophin releasing factor. PMID- 4216622 TI - A study of biogenic amine metabolites in the cerebrospinal fluid and urine of monkeys with chlorpromazine-induced dyskinesia. PMID- 4216621 TI - Vaccinia virus polypeptide synthesis: sequential appearance and stability of pre- and post-replicative polypeptides. PMID- 4216624 TI - Treatment of congenital chylothorax. PMID- 4216623 TI - Heterogeneity of the glial fibrillary acidic protein in gliosed human brains. PMID- 4216625 TI - Solitary neonatal hepatic abscess. AB - A solitary hepatic abscess was found at postmortem examination in a neonate who died at 25 days of age. Elevation of the right diaphragm was noted radiologically from the first day of life, suggesting congenital presence of the abscess. Recognition of the previously unsuspected association between hepatic abscess and congenital diaphragmatic elevation might have led to surgical intervention and have increased the infant's chance of survival. PMID- 4216626 TI - Detection of endotoxemia with the Limulus test: preliminary studies in severely malnourished children. AB - Eighteen Peruvian children with protein-calorie malnutrition were studied to evaluate the usefulness of the limulus assay for endotoxin in detecting gram negative sepsis. Nine of the children had at least one positive Limulus assay, and eight of this group had bacteriologic cultures indicative of gram-negative infection. Four of these nine children with positive Limulus assays died, whereas only one of the nine children with negative assays died. This preliminary study suggests the usefulness of the Limulus assay as an adjunct to bacteriologic cultures in the early detection of significant gram-negative infection in severely malnourished children. PMID- 4216627 TI - Intracellular sodium and potassium concentrations in toad and frog oocytes during development. AB - 1. During growth of oocytes of Bufo bufo from approximately 700-2000 mum in diameter, intracellular Na rose from 20 to 120 m-mole/l. cell water while K fell from 120 to 15 m-mole/l. cell water.2. In Rana temporaria Na similarly rose from 9 to 190 m-mole/l. cell water and K fell from 126 to 28 m-mole/l. cell water.3. At the same time in both Bufo and Rana the ouabain-sensitive Na efflux, the ouabain-insensitive Na efflux, and the total Na influx all increased.4. It is concluded that the predominant process is an increase of passive Na permeability. The increase of apparently active Na efflux may be secondary to the consequent rise in intracellular Na. PMID- 4216628 TI - Intracellular sodium and potassium concentrations in oocytes of Bufo bufo at the beginning of maturation. AB - 1. During the first phase of maturation in oocytes of Bufo bufo, after the growth phase but before ovulation, intracellular Na rises to 120 m-mole/l. cell water while K falls to 15 m-mole/l. cell water.2. At the same time, the ouabain insensitive Na efflux and total Na influx both increase while the ouabain sensitive Na efflux is unchanged. PMID- 4216629 TI - Proceedings: The response of neurones in the pre-central cortex to an unexpected disturbance of finger position. PMID- 4216630 TI - [Neurofibromatous tumor extending into the pelvis]. PMID- 4216631 TI - Normal T cell population in chronic lymphocytic leukemia: analysis of phytohemagglutinin dose-response curves. PMID- 4216632 TI - The St. Kitts vervet (Cercopithecus aethiops). PMID- 4216633 TI - BCG immunization in marmosets. PMID- 4216634 TI - Pathways for movement of ions and water across toad urinary bladder. II. Site and mode of action of vasopressin. PMID- 4216635 TI - Interrelationship of H+ excretion and Na+ reabsorption in the toad urinary bladder. PMID- 4216637 TI - Recurrent radial nerve palsy. PMID- 4216636 TI - Effect of fixatives on fracture plane in red blood cells. PMID- 4216638 TI - Structure of a dimeric fragment related to the lambda-type Bence-Jones protein: a preliminary study. PMID- 4216639 TI - Protein-protein proximity in the association of ribosomal subunits of Escherichia coli: crosslinking of 30 S protein S16 to 50 S proteins by glutaraldehyde or formaldehyde. PMID- 4216640 TI - Strjcture of human plasma prealbumin at 2-5 A resolution. A preliminary report on the polypeptide chain conformation, quaternary structure and thyroxine binding. PMID- 4216641 TI - Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse. PMID- 4216643 TI - Membrane-bound polyribosomes in HeLa cells: association of polyadenylic acid with membranes. PMID- 4216645 TI - [Acute mercury poisoning after bladder lavage using mercury oxycyanide (3 cases)]. PMID- 4216644 TI - [Pyelogenic cysts: dysembryoplastic cysts?]. PMID- 4216647 TI - [Usual harmlessness of endovesical instillations of thio-tepa]. PMID- 4216646 TI - [Bladder lesions due to local administration or ingestion of antiseptic, cytostatic and radioactive compounds]. PMID- 4216648 TI - [Spontaneously cured pancytopenia due to intravesical thio-tepa, apropos of one case]. PMID- 4216649 TI - [Fatal bone marrow aplasia due to endovesical thio-tepa]. PMID- 4216650 TI - [Ureteral metastasis from a cutaneous melanocarcinoma]. PMID- 4216651 TI - [Biological characteristics of Lactobacillus. II. Tolerance of a multiple antibiotic resistant strain, Lactobacillus casei PSR 3002, to artificial digestive fluids]. PMID- 4216652 TI - [A case of lymphosarcoma with two kinds of M-components (IgG-kappa and IgM-kappa (author's transl)]. PMID- 4216653 TI - [Clinical significance of duodenal diverticulosis. 1. Functional and morphological effects on the biliary tract and pancreas]. PMID- 4216654 TI - [Studies on experimental PCB poisoning--dose response effect of PCB and synergistic effect with PCB and ABS (authors' transl)]. PMID- 4216655 TI - New Japanese variant of human erythrocyte carbonic anhydrase. PMID- 4216656 TI - Serologic relationship of coxsackie A-16 viruses from the epidemic of hand-foot and mouth disease in Japan, 1970, to the prototype strain. PMID- 4216658 TI - [Reevaluation of the nurse's attitude in understanding patients]. PMID- 4216657 TI - [Survey on neonatal jaundice]. PMID- 4216660 TI - [Home nursing of a patient with cerebral apoplexy]. PMID- 4216659 TI - [Information concerning patients, and nursing actions]. PMID- 4216661 TI - [Conference: a psychological approach in nursing of a hostile child with ambulatory difficulties due to muscular dystrophy]. PMID- 4216662 TI - [Introduction and study of foreign literature: "Dyspnea" by Marilyn Chrisman]. PMID- 4216663 TI - [Nursing of a patient with anorexia nervosa-an attempt to establish rapport with the patient]. PMID- 4216664 TI - [The theory of assistance-lessons in modern counseling. 10. On understanding]. PMID- 4216665 TI - [The national health care budget for 1972]. PMID- 4216667 TI - [Environment and the human body. 7. Environmental pollution and management of the problem (1)]. PMID- 4216666 TI - [Introduction to human genetics. 10. The etiological background of abnormalities. (2)]. PMID- 4216668 TI - [Introduction to the study of homeostasis. 10. Homeostasis at the cellular level]. PMID- 4216669 TI - [Abnormal personality. 7. Various types of personality abnormalities. (2)]. PMID- 4216671 TI - [Bedside nursing: toilet training of children with cerebral palsy and mental retardation]. PMID- 4216670 TI - [Bedside nursing: assistance in activities of daily living of children serverely affected with cerebral palsy]. PMID- 4216672 TI - [Bedside nursing: nursing of aged patients undergoing hemodialysis therapy. A case complicated by a speech disorder and hemiplegia]. PMID- 4216673 TI - [Nursing practice in the CCU. 1. An emergency case with with acute chest pain]. PMID- 4216674 TI - [Introduction of foreign literature and its discussion. "Bowel Sounds" by Jean Willacker]. PMID- 4216675 TI - [Theory of assistance-lessons in modern counseling. 7. A definition of a mentally sound man]. PMID- 4216676 TI - [The ratios of physician and nurse manpower]. PMID- 4216677 TI - [Introduction to human genetics. 7. Paternity cases and mistaken identity of newborn infants]. PMID- 4216679 TI - [Introduction to homeostasis. 7. Adaptation and antagonism in biological regulation]. PMID- 4216678 TI - [Environment and human body. 4. Light, electromagnetics and the human body]. PMID- 4216680 TI - [Abnormal personality. 4. Background in the development of abnormal personality. 2]. PMID- 4216681 TI - [A nurse's experience as a patient. As an inpatient for 100 days]. PMID- 4216682 TI - [Discussion: home nursing care]. PMID- 4216684 TI - [Home nursing of patients at a city in Toyama Prefecture]. PMID- 4216683 TI - [Home nursing of aged bed-ridden patients. Home nursing activities at Higashi Murayama-Shi, Tokyo]. PMID- 4216685 TI - [Practice of home nursing in the United States]. PMID- 4216686 TI - [Bedside nursing: Nursing of a patient with Buerger's disease associated with persistent pain]. PMID- 4216688 TI - [Bedside nursing: nursing of leukemia patients]. PMID- 4216687 TI - [Bedside nursing: Assistance of an emaciated, schizophrenic patient in her adaptation to the hospital environment]. PMID- 4216689 TI - [Bedside nursing: nursing of a patient with esophagostomy]. PMID- 4216690 TI - [Conference: an aged patient with various complaints but without active desire for recovery]. PMID- 4216691 TI - [Introduction of foreign literature and its discussion. "Reaction Time in the Elderly" by Barbara Greenberg]. PMID- 4216692 TI - [Theory of assistance--lessons in modern counseling. 8. A total picture of the helping relationship]. PMID- 4216693 TI - [Practice of nursing in the CCU. 2. A case of atrial block]. PMID- 4216694 TI - [Reasons for applying for public assistance. Illness and injuries as reasons in 77 percent of the applicants]. PMID- 4216695 TI - [Introduction to human genetics. 8. Effect of radiation on genetics]. PMID- 4216696 TI - [Environment and human body. 5. Noise, vibration and the human body]. PMID- 4216697 TI - [Introduction to homeostasis. 8. Homeostasis of the body fluids--regulation by blood sugar]. PMID- 4216698 TI - [Abnormal personality. 5. Background in the development of abnormal personality. 3]. PMID- 4216699 TI - [Psychology of the aged patient and the nursing approach]. PMID- 4216700 TI - [Abnormal personality. 6. Various types of abnormalities. 1]. PMID- 4216702 TI - [A nurse as a patient. Interest in nursing stimulated by inpatient experience]. PMID- 4216701 TI - [Practice of nursing in the CCU. 3. A case of tachycardia]. PMID- 4216703 TI - [An experience at a CCU training course in the United States]. PMID- 4216704 TI - [Discussion: apprehension of the patient and nursing care]. PMID- 4216705 TI - [A nursing student facing death--a record by a dying student nurse]. PMID- 4216706 TI - [Bedside nursing: assistance of an aged, lonely patient in planning meaningful daily activities in the hospital]. PMID- 4216707 TI - [Beside nursing: approach to an aged, uncommunicative patient]. PMID- 4216708 TI - [Bedside nursing: psychological assistance of a male patient with breast cancer]. PMID- 4216709 TI - [Bedside nursing: conference with family members on diet therapy of a patient with chronic kidney failure]. PMID- 4216710 TI - [Conference: standardization of nursing records]. PMID- 4216711 TI - [introduction of foreign literature and its discussion. "Touching is Talking" by Irene Burnside]. PMID- 4216712 TI - [Speech training of aphasic patients]. PMID- 4216713 TI - [Theory of assistance--lessons from modern counseling. 9. Acceptance and respect]. PMID- 4216714 TI - [Public's desire for increased consumption of various food items]. PMID- 4216715 TI - [Introduction to human genetics. 9. Development of abnormalities. 1]. PMID- 4216716 TI - [Environment and human body. 6. Radiation and the human body]. PMID- 4216717 TI - [Introduction to homeostasis. 9. Body temperature regulation mechanism as a thermostat of the body]. PMID- 4216718 TI - [Rehabilitation in chronic diseases. Nursing problems of children hospitalized for an extended period and special nursing activities]. PMID- 4216719 TI - [2 cases of pericardial diverticulum]. PMID- 4216720 TI - Long-term therapy of hereditary angioedema (HAE). Preventive management with fluoxymesterone and oxymetholone in severely affected males and females. PMID- 4216721 TI - [Tuberculostatic factor in human urine (author's transl)]. PMID- 4216722 TI - [Proceedings: Immunologic mechanism of lymphocytes and macrophages against mycobacterium tuberculosis]. PMID- 4216723 TI - Absence of antinatriferic and natriuretic activity in plasma ultrafiltrates (mol wt less than 50,000) and dialysates from volume-expanded dogs. PMID- 4216724 TI - [Methods of prevention of complications of catheterization of the major veins]. PMID- 4216725 TI - [Principles of treatment of acute diffuse peritonitis in the postoperative period]. PMID- 4216726 TI - [Puncture catheterization of the subclavian vein]. PMID- 4216727 TI - [The biological activity of a thyrotropin-releasing hormone (TRH) derivative (author's transl)]. PMID- 4216728 TI - Convenient micro system for double diffusion immuno precipitin tests. PMID- 4216729 TI - Activity of some lysosomal enzymes in Hurler's syndrome (type i mucopolysaccharidosis). PMID- 4216730 TI - Current practice with vitamin K antagonist therapy. PMID- 4216734 TI - [Device for forming uniform dosage fields with maximal coefficient of the use of electrons]. PMID- 4216735 TI - The use of anti-human haemoglobin in forensic serology. PMID- 4216736 TI - [Sterilization of medical instruments, made of thermolabile materials, with chemical solutions]. PMID- 4216737 TI - The action of pure phospholipases on native and ghost red cell membranes. PMID- 4216739 TI - Isolation of spectrin from erythrocyte membranes. PMID- 4216738 TI - Phospholipase C (phosphatidylcholine cholinephosphohydrolase, EC 3.1.4.3) from Bacillus cereus. PMID- 4216740 TI - Cell adhesion. PMID- 4216741 TI - Cell layer assay. PMID- 4216742 TI - Cations, antibiotics, and membranes. PMID- 4216743 TI - [Effect of activators and inhibitors on the lipase activity of fungi of the genus Geotrichum]. PMID- 4216744 TI - [Biosynthesis of an enzyme with lipoprotein lipase activity by bacterial strains of Pseudomonas genus]. PMID- 4216745 TI - [Inhibition by penicillin and cephalosporin analogs of Staphylococcus aureus beta lactamase using as substrates: benzylpenicillin, ampicillin and carbenicillin]. PMID- 4216746 TI - [Dynamics of decomposition of labeled algae by bacteria]. PMID- 4216747 TI - The photometric titration of Fe(III) with EDTA using Tiron indicator. PMID- 4216748 TI - The use of substituted hydrazones as metallochromic indicators: the EDTA titration of copper. PMID- 4216749 TI - [BACTERIA OF THE GENUS Pseudomonas that assimilate ethanol]. PMID- 4216750 TI - [Choice of factors regulating the growth of monocultures in "controlled association"]. PMID- 4216751 TI - [Blood circulation and hemodynamics of heart in angina pectoris]. PMID- 4216752 TI - [Familial hypoparathyroidism (author's transl)]. PMID- 4216754 TI - [Bacterial contamination of breast-milk obtained by electric pump (author's transl)]. PMID- 4216753 TI - [Hyperosmolar coma]. PMID- 4216755 TI - [Australia-(hepatitis-B-) antigen. Properties and clinical significance]. PMID- 4216756 TI - A comparison by gel diffusion of the Lancefield and Rantz extraction techniques used in grouping haemolytic streptococci. PMID- 4216757 TI - An assessment of an automated immunoprecipitin technique for the measurement of immunoglobulins G, A and M. PMID- 4216758 TI - Physico-chemical characterisation of rinderpest virus. PMID- 4216759 TI - Defective interfering particles produced during the replication of measles virus. PMID- 4216761 TI - Variants of measles virus. PMID- 4216760 TI - SSPE measles virus: non-productive and productive infection in Vero cells and suckling mice. PMID- 4216762 TI - [Retrospection on the epidemiological situation of tuberculosis]. PMID- 4216763 TI - Restriction and modification in Bacillus subtilis. Induction of a modifying activity in Bacillus subtilis 168. PMID- 4216764 TI - Genetic instability in Drosophila melanogaster. Evidence for insertion mutations. PMID- 4216765 TI - Genetic instability in Drosophila melanogaster. A mutable tandem duplication. PMID- 4216766 TI - Establishment of a correlation between physical molecule and genetic map in one segment of the SPP1 chromosome. PMID- 4216767 TI - The ribosomal proteins of Drosophila melanogaster. Localization of stage specific proteins on the small and large ribosomal subunit. PMID- 4216768 TI - Mutual regulation of magnified bobbed loci in Drosophila melanogaster. PMID- 4216769 TI - UV-sensitivity and UV-mutability of infectious lambdaDNA: reactivation, protection and mutability in various assay systems. PMID- 4216770 TI - Tetanus toxin conformation. PMID- 4216771 TI - [Topical clinical problems of vitamin D research (author's transl)]. PMID- 4216772 TI - [Pulse reactions in short bursts of acceleration during a switchback ride. Experiences with the use of a nobile ECG storage recorder (author's transl)]. PMID- 4216773 TI - [Impedance cardiography. Importance of the method and its limitations (author's transl)]. PMID- 4216774 TI - [Results of a new method for the analysis of cardiac rhythm (author's transl)]. PMID- 4216775 TI - [Prevention of pacemaker-induced muscle twitching (author's transl)]. PMID- 4216776 TI - [Synopsis of medical psychology (author's transl)]. PMID- 4216777 TI - [Effects of Etilefrin on clinico-chemical findings]. PMID- 4216778 TI - [Treatment of heart failure with vasodilator drugs]. PMID- 4216779 TI - [Simplification of allopurinol treatment]. PMID- 4216780 TI - [Letter: Tympanic effusion following otitis media]. PMID- 4216781 TI - [Letter: Changes of deepfrozen foodstuffs]. PMID- 4216782 TI - [Editorial: Phoniatry, pedoaudiology I]. PMID- 4216783 TI - [Vocal disturbances after treatment with androgenic and anabolic hormones (author's transl)]. PMID- 4216784 TI - [Occupational vocal disorders (author's transl)]. PMID- 4216785 TI - [Speech disorders in childhood (author's transl)]. PMID- 4216786 TI - [Logopedic treatment of disorders of speech, voice and hearing (author's transl)]. PMID- 4216787 TI - [Psychological principles in disorders of speech and speaking (author's transl)]. PMID- 4216788 TI - [About aphasia (author's transl)]. PMID- 4216789 TI - [Modern pedo-audiology (author's transl)]. PMID- 4216790 TI - [Unrecognized hearing disorders in childhood (author's transl)]. PMID- 4216791 TI - [The history of ventriloquism (author's transl)]. PMID- 4216793 TI - [A contribution on the treatment of traumatic shock (author's transl)]. PMID- 4216792 TI - [Disturbances of acid-base equilibrium, their recognition and treatment (author's transl)]. PMID- 4216794 TI - [The development of lithotomy (author's transl)]. PMID- 4216795 TI - [Experiences in the percutaneous use of iodine-iodine-potassium]. PMID- 4216796 TI - [Otorhinolaryngology. Rhinology]. PMID- 4216797 TI - [Cerebral aneurysms in stenosis of the aortic isthmus and references to other neurological complications of this disease (author's transl)]. PMID- 4216798 TI - [Possibilities for operative treatment of tumors of the vertebral column (author's transl)]. PMID- 4216800 TI - [The diagnosis of epilepsies: the advantage of a new classification (author's transl)]. PMID- 4216801 TI - [Petit mal in old age? (author's transl)]. PMID- 4216799 TI - [Indications for neurological pain-relieving operations (author's transl)]. PMID- 4216802 TI - [Epilepsy and multiple sclerosis (author's transl)]. PMID- 4216804 TI - [Erythema chronicum migrans meningitis - a bacterial infectious disease? (author's transl))]. PMID- 4216803 TI - [Immunsuppressive treatment of multiple sclerosis. 2. Critical review of general results (author's transl)]. PMID- 4216805 TI - [The question of early failure with early mobilised patients with myocardial infarction (author's transl)]. PMID- 4216806 TI - [Do correlations exist between coffee drinking and myocardial infarction? (author's transl)]. PMID- 4216807 TI - [Doppler testing of the function of venous valves and varicosis (author's transl)]. PMID- 4216808 TI - [The importance of auscultation of the abdominal unpaired visceral arteries (author's transl)]. PMID- 4216809 TI - [Clinical experiences with a combination therapy of metastasising genital and mammary carcinomas (author's transl)]. PMID- 4216810 TI - [The treatment of metastasising mammary carcinoma with drostanolone propionate (masterid) (author's transl)]. PMID- 4216811 TI - [Immunoglobulin D and IgD plasmacytoma (author's transl)]. PMID- 4216812 TI - [Implantation of fetal thymus tissue in patients with progressive malignant neoplasms (author's transl)]. PMID- 4216813 TI - [Unusual echinococcus disease attacking the heart and brain (author's transl)]. PMID- 4216814 TI - [A case of Diamond-Blackfan anemia: Experiences of 10-year follow-up study]. PMID- 4216815 TI - [Infection of towns in the middle ages. (Pollution of the environment in the past) (author's transl)]. PMID- 4216816 TI - [Effect of furosemide-induced increased diuresis on the pharmacodynamics of ampicillin]. PMID- 4216817 TI - [Iron metabolism, iron deficiency and iron therapy (author's transl)]. PMID- 4216818 TI - [Letter: Is the "imperial Vaccination Act" out-of-date?]. PMID- 4216819 TI - [Letter: Hypertension and psychosomatic medicine]. PMID- 4216820 TI - [Letter: Supplementary drug therapy in smoking withdrawal]. PMID- 4216822 TI - [Letter: Absorption of lead by plants?]. PMID- 4216821 TI - [Letter: The problem of cancer]. PMID- 4216823 TI - [Immunosuppressive treatment of multiple sclerosis. 3. Results of treatment with azathioprine and antilymphocytic globulin (author's transl)]. PMID- 4216824 TI - [Myopathy and osteomalacia after longterm antiepileptic treatment (author's transl)]. PMID- 4216825 TI - [Voluntary detoxification therapy of young drug addicts in a medical clinic (author's transl)]. PMID- 4216826 TI - [The problems of amphetaminil (AN1) abuse (author's transl)]. PMID- 4216827 TI - [The activity of the nootropic substance piracetam on the cortical performance of chronic alcoholics (author's transl)]. PMID- 4216829 TI - [In memoriam V. E. Mertens]. PMID- 4216828 TI - [Results of physical therapy of peripheral arterial circulatory disorders (IV)(author's transl)]. PMID- 4216831 TI - [The treatment of navicular fractures and pseudarthrose with electric and magnetic potentials]. PMID- 4216832 TI - [A contribution on gallstone ileus]. PMID- 4216830 TI - [Hand injury due to heat and simultaneous pressure ("ironing machine injury")]. PMID- 4216833 TI - [An investigation of the effectiveness of the training of ambulance personnel]. PMID- 4216834 TI - [Annual report on the use of the Kaiserslautern emergency ambulance (16. 4. 1973 30. 1974)]. PMID- 4216835 TI - D-penicillamine in reconstructice surgery of the biliary tract. PMID- 4216836 TI - [Cystoscopic transurethral incision of urethral stricture with a sharp instrument (author's transl)]. PMID- 4216837 TI - [Improvement of renal function during temporary dialysis treatment in patients with chronic interstitial nephritis (author's transl)]. PMID- 4216838 TI - [Acute renal failure after rifampicin (author's transl)]. PMID- 4216839 TI - [Ureteral stenosis caused by periarterial fibrosis in arteriosclerosis (the differential diagnosis of fibrous ureteral stenoses) (author's transl)]. PMID- 4216841 TI - [In memoriam Werner Bickenbach]. PMID- 4216840 TI - [Analysis of the microscopic structure of urinary calculi (author's transl)]. PMID- 4216842 TI - [Proceedings: Benign and malignant gastric tumors. Pathologico-anatomical review]. PMID- 4216843 TI - [Proceedings: Surgical treatment of benign gastric tumors]. PMID- 4216844 TI - [51st Convention of the Bavarian Surgical Society in Munich, July 19-20, 1974]. PMID- 4216845 TI - [Proceedings: Surgical treatment of malignant gastric tumors]. PMID- 4216846 TI - [Proceedings: Gastric-stump and anastomosis carcinoma]. PMID- 4216847 TI - [Proceedings: Carcinoma in the resected stomach]. PMID- 4216848 TI - [Proceedings: Clinical follow-up in carcinoma patients following gastrectomy]. PMID- 4216849 TI - [Proceedings: Early stomach carcinoma from the surgical viewpoint]. PMID- 4216850 TI - [Proceedings: Early cancer of the stomach. Diagnosis and surgical sequelae]. PMID- 4216851 TI - [Proceedings: Diagnostic value of secretion analysis in gastric tumors]. PMID- 4216852 TI - [Proceedings: Diagnosis, therapy and pathologic value of gastric polyps]. PMID- 4216853 TI - [Proceedings: Pseudomalignant gastric tumors in isolated involvement of Crohn's disease]. PMID- 4216854 TI - The survival of microfungi in the nests of tree-sparrow (Passer montanus L.) in the nest-boxes over the winter season. PMID- 4216855 TI - [Possibility of diagnosis of lung adiaspiromycosis]. PMID- 4216856 TI - Glyoxalase system enzyme activity in the liver of rats fed dimethylaminoazobenzene. PMID- 4216857 TI - Monoclonal IgG-kappa cryoimmunoglobulin in a woman patient with lymphoreticular series hemoblastosis. PMID- 4216858 TI - [Copper metabolism disorders in cerebral convulsions]. PMID- 4216859 TI - Effect of nicotine and other drugs on the release of 3H-norepinephrine and 3H dopamine from rat brain slices. PMID- 4216860 TI - Language and brain: developmental aspects. PMID- 4216861 TI - Symptomatic ossification of the posterior longitudinal ligament of the cervical spine. Clinical findings. PMID- 4216862 TI - Medicaid prepayment: concept and implementation. PMID- 4216864 TI - Regional health authorities. PMID- 4216863 TI - [Use of ultrasonics in the diagnosis of anti-Rh isoimmunization]. PMID- 4216865 TI - The performance of an anti D immunoprophylaxis scheme. PMID- 4216866 TI - Factors in the causation and incidence of ovarian cancer. PMID- 4216867 TI - Estriol in pregnancy. PMID- 4216868 TI - Human prolactin: secretion, regulation and pathophysiology. PMID- 4216869 TI - Tyrosinase activity of aqueous humour in uveal melanoblastoma. PMID- 4216870 TI - Reaction of the exposed pulp to Dycal treatment. PMID- 4216871 TI - [Hemolysin of Listeria monocytogenes (listeriolysin)]. PMID- 4216872 TI - [Pharmacodynamics of the cerebral circulation. Results of a study on the action of 10 drugs on cerebral blood flow and energy metabolism in cerebrovascular patients]. PMID- 4216873 TI - [Proceedings: Induction of N2-acetylornithine-5-aminotransferase in Pseudomonas aeruginosa with arginine]. PMID- 4216874 TI - Total body potassium estimations in young children: the interpretation of results. PMID- 4216875 TI - Distribution of PCB and p,p'-DDE residues in Atlantic herring (Clupea harengus harengus) and yellow perch (Perca flavescens) in Eastern Canada--1972. PMID- 4216876 TI - Residues of the insecticide mirex in terrestrial and aquatic invertebrates following a single aerial application of mirex bait, Louisiana--1971-72. PMID- 4216877 TI - Pesticide residue levels in soils and crops, FY-70--national soils monitoring program (II). PMID- 4216878 TI - [Whole body counting of 131I administered patients with hyperthyroidism, and estimations of absorbed doses of 131I to various organs (author's transl)]. PMID- 4216879 TI - [Intercomparison of high energy radiation dosimetry in Japan. I. Preliminary intercomparison of high energy electron dosimetry (author's transl)]. PMID- 4216880 TI - [Intercomparison of high energy radiation dosimetry in Japan. II. Intercomparison of JAPM sub-standard dosimeters and absorbed dose for high energy electrons (author's transl)]. PMID- 4216881 TI - [Hodgkin's disease. Treatment of localized forms I and II using a combination of radiotherapy and chemotherapy]. PMID- 4216882 TI - [Mesenteric compression syndrome in undernourished patients. Value of parenteral hyperalimentation]. PMID- 4216884 TI - [Letter: When will an anti meningococcic vaccine be available?]. PMID- 4216883 TI - [Physiology of T.R.H. secretion. Recent data]. PMID- 4216885 TI - [Letter: Ambulatory enteral nutrition. A new method]. PMID- 4216886 TI - [Letter: Steroid-induced diabetes]. PMID- 4216887 TI - [Septicemia due to bacillus cereus. Pathogenicity of bacteria of the genus bacillus]. PMID- 4216888 TI - [Role of magnesium in the physiology and pathology of myocardial cells]. PMID- 4216889 TI - [Intal in the treatment of ulcerative colitis]. PMID- 4216890 TI - I-cell disease--mucolipidosis II. PMID- 4216891 TI - [Study of serum IgE during allergic asthmas (except pollinosis), non-allergic asthmas and chronic bronchitis, and of their modification through sodium cromoglycate]. PMID- 4216893 TI - [A behavior therapeutic program for adult stutterers]. PMID- 4216892 TI - Some problems in cancer management. The Michael Williams Lecture 1974. PMID- 4216894 TI - [Immunodiagnosis of filariasis]. PMID- 4216895 TI - Isolation of higher molecular weight DNA from Bacillus Cereus T using proteinase K. PMID- 4216896 TI - Isolation and characterization of a temperature sensitive protein from dog colostrum and milk. PMID- 4216897 TI - [Prognosis of the effectiveness of treatment of pulmonary tuberculosis]. PMID- 4216899 TI - [Ways of increasing inoculation and growth acceleration of Mycobacterium tuberculosis]. PMID- 4216898 TI - [Effect of rifampicin on the intra- and extracellularly located Mycobacterium tuberculosis]. PMID- 4216900 TI - Effect of androgens on the red cell 2, 3 diphosphoglycerate hemoglobin oxygen affinity and red cell mass in mammals. PMID- 4216901 TI - Virulence measurements of Pseudomonas aeruginosa based on plaque and toxin Z formation in cell culture. PMID- 4216902 TI - Effect of the H37Ra strain of M. tuberculosis and of a mycobacterial RNA fraction on tumor growth. PMID- 4216903 TI - The study of shea butter. 4. Stability of medicaments in shea butter ointments and creams. PMID- 4216904 TI - The action of ergot alkaloids (ergotamine and dihydroergotoxin) on the functional effects of cerebral ischemia in the cat. PMID- 4216905 TI - The psychiatrist attitudes and therapeutic means when faced with resistant depressions. PMID- 4216907 TI - A theoretical evaluation of plastic dosimetry phantoms. PMID- 4216906 TI - [Changes in psychodynamics of manic-depressive diseases through the long-term administration of lithium salts]. PMID- 4216908 TI - A standard system of coordinates for radiotherapy apparatus. HPA Radiotherapy Physics Topic Group. PMID- 4216909 TI - The application of the logarithmic response of silicon diodes to monitoring beam symmetry and electron energy. PMID- 4216910 TI - Limitations of the use of the geometric mean to obtain depth independence in scanning and whole body counting. PMID- 4216912 TI - Pion dose calculations suitable for treatment planning. PMID- 4216911 TI - Heavy particles in therapy: an application of track theory. PMID- 4216914 TI - Spectral dependence of the FeSO4 G-value in DT neutron beams. PMID- 4216913 TI - Energy calibration of high energy electrons using a Cerenkov detector and a comparison with different methods. PMID- 4216915 TI - Excited states and photobiological properties of potential DNA cross-linking agents, the benzodipyrones. PMID- 4216916 TI - [Neutralization of the sputum in newly detected patients with pulmonary tuberculosis treated during the years 1967 to 1970]. PMID- 4216918 TI - [Comparison vaccines prepared from 3 various strains of BCG-A]. PMID- 4216917 TI - [Fate of BK (Bacterium Koch)-positive patients discovered during the past 11 years]. PMID- 4216919 TI - [Epidemiologic aspects of resistance to ATA (Antitubercular Agents)]. PMID- 4216920 TI - [Differential diagnosis of the post-tubercular syndrome and bronchial cancer]. PMID- 4216921 TI - [Immunoglobulin E in the etiologic differentiation of chronic obstructive lung disease]. PMID- 4216922 TI - [Speed of conversion sputum in the culture of sensitive and resistant organisms]. PMID- 4216923 TI - [Resistance to antitubercular agents in patients with pulmonary tuberculosis treated in the period from 1967 to 1970]. PMID- 4216924 TI - [Results of hospital treatment in soldiers of the YNA (Yugoslavian National Army) suffering from acute pulmonary tuberculosis in the period from 1955 to 1964]. PMID- 4216925 TI - An observational study of hallucinogen-induced behavior in unrestrained Macaca mulatta. PMID- 4216926 TI - The hypothalamus and behavioral patterns. PMID- 4216927 TI - Structure and fiber connections of the hypothalamus in mammals. PMID- 4216928 TI - Parenteral nutrition. PMID- 4216929 TI - Techniques of total intravenous feeding. A comment to the paper by F. Jarrett. PMID- 4216930 TI - [Antineoplastic chemotherapy associated with gastric cancer surgery]. PMID- 4216931 TI - [New basis for the surgical treatment of megaesophagus: esophagocardiomyotomy with esophagus-fundus-gastropexy]. PMID- 4216932 TI - [Laboratory accidental diagnosis of unsuspected acute chagasic infection post blood transfusion]. PMID- 4216933 TI - [New reservoirs of Trypanosoma cruzi]. PMID- 4216935 TI - [New reservoirs of Trypanosoma cruzi]. PMID- 4216934 TI - [Studies of wild reservoirs and vectors of Trypanosoma cruzi. LIV. Natural bat infection, Epitesicus brasiliensis brasiliensis (Desmarest, 1819) by T. cruzi]. PMID- 4216936 TI - [Polyacrylamide gel block electrophoresis of human serum lipoproteins, II. Immunological study (author's transl)]. PMID- 4216937 TI - [Etiological diagnosis of obstructive and hepatocelullar jaundice. Review of 100 cases]. PMID- 4216938 TI - Protection of microsomal drug biotransformation enzymes against carbon tetrachloride by diethyldithiocarbamate in rat liver. PMID- 4216939 TI - Theileria lawrencei infection of cattle and African buffalo: evaluation of a buffalo cell culture schizont antigen for the indirect fluorescent antibody test. PMID- 4216940 TI - Immunogenicity of mycoplasma galactan. PMID- 4216941 TI - [Chagas' disease in the State of Jalisco: Mexican Republic. Report of 3 new human cases]. PMID- 4216942 TI - [Combined chemotherapy and immunotherapy in the short treatment of tuberculosis]. PMID- 4216943 TI - [Optimal immunization for the industrial production of equine tetanus antitoxin by way of complete Freund's adjuvant and the frequency of antigen stimulation]. PMID- 4216944 TI - [Pituitary adenoma with thyreotropic cells]. PMID- 4216945 TI - [2 step course of a pituitary adenoma: amenorrhea-galactorrhea syndrome then Cushing's disease]. PMID- 4216946 TI - [Hypothalamic neuronal activity and water balance regulation]. PMID- 4216947 TI - [Esophageal carcinoma in chagasic mega-esophagus after Merendino's operation]. PMID- 4216949 TI - [Ischemic colitis: a complication of megacolon surgery]. PMID- 4216948 TI - [Contribution to the vectorcardiographic study of the left anterior fascicular block in chronic Chagas' heart disease]. PMID- 4216950 TI - [Subcaloric alimentation with special reference to alimentation under shipwreck condition at sea (author's transl)]. PMID- 4216951 TI - [Treatment of Hodgkin's disease. General principles]. PMID- 4216952 TI - [Radiotherapy in Hodgkin's disease. Practical aspects]. PMID- 4216953 TI - [Hodgkin's disease in the practice of general medicine. Problems posed by the diagnosis, surveillance of treatments and social rehabilitation of patients]. PMID- 4216954 TI - [Paragonial proteins in the mature male of Drosophila melanogaster: electrophoretic pattern and in vitro synthesis]. PMID- 4216956 TI - [Familial disorders of thyroxin-binding globulin as a cause of misleading serum thyroxin values. A study of 6 families]. PMID- 4216955 TI - [Short- or long-term antibiotic therapy in chronic pyelonephritis]. PMID- 4216957 TI - [Bone-marrow toxicity, lactic acidosis, and disseminated intravascular coagulation following phenformin medication]. PMID- 4216958 TI - Experiences with a new test of exocrine pancreatic function in protein deficient Patas monkeys. PMID- 4216959 TI - The economic approach to family health studies. PMID- 4216960 TI - The causes of the disappearance and reappearance of induced sublethal mutations in Drosophila melanogaster in the course of a number of generations. PMID- 4216961 TI - An anatomical study of the pineal body of the vervet monkey (Cercopithecus aethiops). PMID- 4216962 TI - A histochemical study of the pineal body of the vervet monkey (Cercopithecus aethiops). PMID- 4216963 TI - Aflatoxin and primary liver cancer. PMID- 4216964 TI - Letter: Effect of measles on the intra-epithelial lymphocyte count of malnourished children. PMID- 4216965 TI - Incidence and spectrum of malnutrition in paediatric hospital wards. PMID- 4216966 TI - [Research in a long-term care department: synthetic lambsskin as an aid in decubitus prevention]. PMID- 4216967 TI - [Care of the dying]. PMID- 4216968 TI - The treatment of advanced cancer by fast neutrons from the Medical Research Council's cyclotron at Hammersmith Hospital, London. PMID- 4216969 TI - RBE values of 15 MeV neutrons for responses of pulmonary metastases in patients. PMID- 4216970 TI - Clinical features of 16 and 50 Mev d leads to Be neutrons. PMID- 4216971 TI - Comparison between neutron therapy and 60Co gamma ray therapy of bronchial, gastric and oesophagus carcinomata. PMID- 4216973 TI - Evaluation of 252Cf neutron emitter for intersitital and intracavitary radiation therapy. PMID- 4216972 TI - The use of californium-252 sources for brachytherapy of human tumours: a preliminary report. PMID- 4216974 TI - Clinical trials with fast neutrons. PMID- 4216975 TI - Registration of clinical data and criteria for selection of patients for fast neutron trials. PMID- 4216976 TI - International cooperation with regard to clinical trials of fast neutron radiotherapy. PMID- 4216977 TI - The Wisconsin Society of Radiation Oncologists' fast neutron treatment facility. PMID- 4216978 TI - Plans for the high-energy, heavy-ion facility (BEVALAC) at Berkeley. PMID- 4216979 TI - Plans for neutron radiotherapy in the radiotherapy department of the University Hospital Hamburg-Eppendorf. PMID- 4216980 TI - Studies of the proteins elutable from certain artificial surfaces exposed to human plasma. PMID- 4216981 TI - [More personnel in long term care will be more humane]. PMID- 4216983 TI - [Ruptures of lateral ligaments of ankle. Primary surgical treatment]. PMID- 4216982 TI - [Diagnosis of gonorrhea in women using culture technic. From which site should the material preferably be taken?]. PMID- 4216984 TI - [Testicular malignancies. Results following megavolt-radio-therapy from 1960 to 1972]. PMID- 4216985 TI - Variation of RBE as a function of depth in a high energy electron beam in the first millimeters of the irradiated tissues determined by the observation of skin reactions on patients (a clinical trial). PMID- 4216986 TI - Skin tolerance in rabbits to alpha particle and low energy electron irradiation. PMID- 4216987 TI - Double-tracer method for determining the proteolytical activity of RES in X irradiated rats using 131I-labelled albumin microspheres. PMID- 4216988 TI - [Possibilities and prospects of radiotherapy using densely ionized particles and neutrons]. PMID- 4216990 TI - [Irradiation planning using computers]. PMID- 4216989 TI - [Radiobiologic principles of radiotherapy with special reference to the treatment with corpuscular radiation]. PMID- 4216991 TI - [Dosimetry and irradiation methods in electron therapy]. PMID- 4216992 TI - [Physical and dosimetric bases of therapy using densely ionized particles and fast neutrons]. PMID- 4216993 TI - [Profile of a modern linear accelerator (linear accelerator SL 75/20)]. PMID- 4216994 TI - [Clinical equipment for neutron therapy using DT-generators (Dynagen)]. PMID- 4216995 TI - [Safety of medical accelerators]. PMID- 4216996 TI - [Measurements of concerning single-field electron irradiation of retrobulbar space of the eye]. PMID- 4216997 TI - Immunodiagnostic tests for bilharziasis. III. Serodiagnosis of Schistosoma haematobium. Infection and influence of chemotherapy on immunodiagnostic tests. PMID- 4216998 TI - Cross-reacting antigens among some Filariae and other nematodes. PMID- 4216999 TI - Exoantigens of Trypanosoma cruzi in vivo. PMID- 4217000 TI - [Sera from Liberia, West Africa, cross reacting with Ascaris, hookworm and Onchocerca antigens (author's transl)]. PMID- 4217001 TI - [Evaluation of the importance of various diseases on mortality]. PMID- 4217002 TI - [Congenital diverticulum of the ureter]. PMID- 4217003 TI - Treatment of chronic cystitis by instillation: experiments employing an artificial model. PMID- 4217008 TI - [Multiple diverticula of the digestive tract]. PMID- 4217011 TI - [Changes in the fragility of erythrocytes during a course of nutrition induced musclular dystrophy in calves]. PMID- 4217010 TI - [Year-round buffering of the feed ration using for dairy cows montmorillonite (Bentonite) and its effect on the health and the hematological and biochemical indices]. PMID- 4217012 TI - [Histological and histochemical study of the porcine liver and kidneys after feeding with monoethanolamine-phosphate]. PMID- 4217013 TI - [Activities of GOT, GPT, SODH and AF enzymes in the blood serum of goats after cesarean section]. PMID- 4217014 TI - [Clinical evaluation of various medicamentous for the immobilization of minks Lutreola vison]. PMID- 4217015 TI - [Activities of alpha-amylase and lipase in Landes goslings during ontogenesis]. PMID- 4217017 TI - Bovine brucellosis in Nigeria. PMID- 4217016 TI - Listeria monocytogenes type 5 as a cause of abortion in sheep. PMID- 4217018 TI - [Clinico-roentgenological indicators of the severity of spondylo-epiphyseal dysplasia]. PMID- 4217019 TI - [Certain criteria of prognosis in radiation therapy of lung cancer]. PMID- 4217020 TI - [Residual amount of sevin, neguvon and imidan in the meat of swine treated against ectoparasites]. PMID- 4217021 TI - [Rumen acidosis and the diabetic syndrome in cattle]. PMID- 4217022 TI - [Biochemical and morphological studies of the blood and liver in cows with ketosis]. PMID- 4217023 TI - [Detection of enterococci dry milk]. PMID- 4217025 TI - A standardized autopsy-protocol--problems and solutions. PMID- 4217024 TI - [Comparative serological and immunoelectric study of Salmonella gallinorum pullorum in deep culture]. PMID- 4217026 TI - Cellular breakdown within the arterial wall. An ultrastructural study of the coronary artery in young and aging rats. PMID- 4217027 TI - The influence of the autonomic nervous system on the ultrastructure of the parotid acinar cells. Experimental contribution to the neurohormonal sialadenosis. PMID- 4217028 TI - Epithelial proliferation and morphogenesis of hyperplastic adenomatous and villous polyps of the human colon. PMID- 4217029 TI - The pathology of pulmonary veno-occlusive disease. PMID- 4217030 TI - Endodermal sinus tumor or orchioblastoma in children and adults. PMID- 4217031 TI - The structure of the glomerular capillary basement membrane in diabetes mellitus with and without nephrotic syndrome. PMID- 4217032 TI - Scanning and transmission electron microscopy observations on the surface lining of aortic intimal plaques in rabbits on a hypercholesterolic diet. PMID- 4217033 TI - Immune insulitis and manifest diabetes mellitus. Studies on the course of immune insulitis and the induction of diabetes mellitus in rabbits immunized with insulin. PMID- 4217034 TI - [Ultrastructure and development of cortical osteocytes. Experimental investigation in the rat (author's transl)]. PMID- 4217035 TI - Calibres of aorta and pulmonary artery in hypoplastic left and right heart syndromes: effects of abnormal bloodflow? PMID- 4217036 TI - Immunofluorescence, histochemical and ultrastructural studies for the detection of multiple endocrine polypeptide tumours of the pancreas. PMID- 4217037 TI - [Electron microscopical studies on an endocrine active carcinoma of the adrenal cortex (author's transl)]. PMID- 4217038 TI - Glomerular changes in acute renal allograft rejection in the dog. PMID- 4217039 TI - Specificity of inhibition of experimental autoallergic lesions of rat salivary glands. PMID- 4217040 TI - Demonstration of percellular channels in glamerular podocytes in aminonucleoside nephosis. PMID- 4217041 TI - The computation of lightness by the primate retina. PMID- 4217042 TI - [Quantitative study and antigenic analysis of the urinary and serum immunoglobulins in children with acquired and hereditary kidney diseases]. PMID- 4217043 TI - [Effect of parenterally administered casein and its hydrolysis products on the exocrine secretion of the pancreas]. PMID- 4217044 TI - [Determination of folacin in the liver by a fluorometric method]. PMID- 4217045 TI - [Economic reserves in public health administration in the Donetsk district]. PMID- 4217046 TI - [Congenital diverticulosis of the stomach]. PMID- 4217047 TI - [Adsorption of cyanophage LPP-1 on cells of the blue-green alga Plectonema boryanum]. PMID- 4217048 TI - [Isolation of type B oncornavirus from a continuous line of human amnion cells]. PMID- 4217049 TI - [Chronic infection of Vero cell cultures with Japanese encephalitis virus. Basic system characteristics]. PMID- 4217050 TI - [Indirect hemagglutination reaction with CHF-Congo group viruses]. PMID- 4217051 TI - [New antigens in human continuous cell lines and neoplasms]. PMID- 4217052 TI - [The diaphragma oris, an embryological and topographical reinvestigation (author's transl)]. PMID- 4217053 TI - [Usefulness of chemical preservatives for semi-quantitative urine culture]. PMID- 4217054 TI - [Modern radiochemical methods for hormone analysis]. PMID- 4217056 TI - Strain tolerance of the vv. cerebri sup. (bridiging veins) calculated from head on collision tests with cadavers. PMID- 4217055 TI - [Catheter-less method of feeding patients following a laryngectomy]. PMID- 4217057 TI - A cage for the successful maintenance of tree shrews (Tupaia belangeri) in captivity. PMID- 4217058 TI - [Chronic salmonella carriers among monkeys]. PMID- 4217059 TI - [Therapy of esophageal perforation and of the so-called spontaneous esophageal rupture]. PMID- 4217060 TI - Bovine congenital skeletal defects. PMID- 4217061 TI - Congenital porta-caval shunts in the dog; a description of three cases. PMID- 4217062 TI - [Radiographic visualisation of parts of the ventricular excitation system of the mammalian heart (author's transl)]. PMID- 4217063 TI - Clinical and pathological observations on five cases of equine sarcoidosis identified in Romania. PMID- 4217064 TI - Some aspects of the cardiovascular physiology of the duck. PMID- 4217065 TI - [Bovine vulval carcinoma in Ceylon (author's transl)]. PMID- 4217066 TI - [The course of the urea cycle in the liver of the chicken (author's transl)]. PMID- 4217067 TI - Blood thiamine levels and transketolase activities as a diagnostic method for thiamine adequacy in cattle. PMID- 4217068 TI - Proteic content of human uterine secretion. PMID- 4217069 TI - [Granulomatous cholesterol salpingitis with ceroid accumulation and osseous metaplasia]. PMID- 4217070 TI - Myeloid cell actinomycin binding in human myeloid leukaemia. PMID- 4217071 TI - [Synthesis of hemoglobin, RNA and DNA in hemolytic anemia, thalassemia and acute anemia following hemorrhage]. PMID- 4217072 TI - Abnormal factor X (factor X Friuli) coagulation disorder. The heterozygote population. A study of 57 subjects. PMID- 4217073 TI - Hereditary elliptocytosis associated with pernicious anaemia. PMID- 4217074 TI - Purpura characterised by thrombasthenia associated with alterations of blood lipids. PMID- 4217075 TI - Capacity of rat haemopoietic colony-forming units to produce differentiated progeny. PMID- 4217076 TI - Distribution of colony-forming cells in mouse bone marrow. PMID- 4217077 TI - Concurrent infectious mononucleosis and acute myelocytic leukemia. PMID- 4217079 TI - PHA response of blood and lymph node lymphocytes in vitro in malignant lymphomas. PMID- 4217078 TI - Rosette-forming lymphocytes in normals and patients with malignant lymphomas. PMID- 4217080 TI - A study of lymphocytic beta-glucuronidase in various benign and malignant lymphatic processes. PMID- 4217082 TI - Hyperalimentation. PMID- 4217081 TI - Water, electrolytes, vitamins and carbohydrates in parenteral nutrition. PMID- 4217084 TI - Intravenous amino acid therapy. PMID- 4217083 TI - Therapy with fat emulsion. PMID- 4217085 TI - Nutrition of medical patients. PMID- 4217086 TI - Parenteral nutrition in uremia. PMID- 4217087 TI - [Immunoelectrophoretic quantitation of the brain specific S-100 protein (author's transl)]. PMID- 4217089 TI - Studies on GM1-gangliosidosis, type II. PMID- 4217088 TI - Enzyme histochemical and ultrastructural alterations in the brains of Friesian calves with GM1 gangliosidosis. PMID- 4217091 TI - Multiple sclerosis--a critique and prospective. PMID- 4217090 TI - The physiological effects of iron deficiency anaemia and malnutrition on exercise performance in East African school children. PMID- 4217092 TI - The background histories of schoolchildren severely malnourished in infancy. PMID- 4217093 TI - Lactose malabsorption: its biology and history. PMID- 4217094 TI - Familial dysautonomia: diagnosis, pathogenesis and management. PMID- 4217095 TI - Venereal disease in children. PMID- 4217096 TI - Standardisation of arthritogenic adjuvants for evaluating anti-inflammatory and immunosuppressant drugs. PMID- 4217097 TI - An improved fixation procedure for microtubules and microfilaments in cells of the anterior pituitary gland. PMID- 4217098 TI - Patterns of protein-energy malnutrition in early childhood in Jordan. PMID- 4217099 TI - Significance of anaerobic spirochetes in the intestines of animals. PMID- 4217100 TI - Lactobacilli which attach to the crop epithelium of the fowl. PMID- 4217101 TI - Nutritional features and ecology of predominant anaerobic bacteria of the intestinal tract. PMID- 4217102 TI - Metabolic interactions among intestinal microorganisms. PMID- 4217103 TI - Microbial bile acid transformation. PMID- 4217104 TI - Serologically active glycolipid families from Mycobacterium bovis BCG. II. Serologic studies on human sera. AB - Serological tests with serologically active glycolipids from Mycobacterium bovis BCG were investigated for their possible use in the diagonis of mycobacterioses. The results were positive with 95 percent of sera from patients with far advanced and moderately advanced tuberculosis, 80 percent of sera from patients with newly diagnosed tuberculosis and 75 percent of patients with atypical mycobacterial diseases. "False" positive serologic reactions were obtained from 4 percent or less. Furthermore, 39 percent of sera from recent tuberculin converters were positive compared with only 9 percent of sera from unselected PPD positive individuals. PMID- 4217105 TI - The human ultraviolet action spectrum. PMID- 4217106 TI - Hemolytic anemia of premature infants associated with vitamin E deficiency. Animal model: hemolytic anemia in monkeys deficient in vitamin E. PMID- 4217107 TI - [Possible clinical importance of immunological difference of plasminogen structures]. PMID- 4217109 TI - [Indicators of histamine and its inactivation in septic puerperal infections]. PMID- 4217108 TI - [Prenatal determination of Rho (D)-phenotype of the fetus according to data of the analysis of amniotic fluid cells]. PMID- 4217110 TI - [Work of the maternity hospital No. 23 specializing in the prevention and treatment of hemolytic disease of newborn]. PMID- 4217111 TI - [Effectof sex steroids on experimental dysplasia of the uterine cervix epithelium and carcinogenesis]. PMID- 4217112 TI - [Study of iodine metabolism in pregnant women and parturients by the radioisotope method in vitro]. PMID- 4217113 TI - [Certain indicators of the oxidation-reduction processes in patients with septic abortions]. PMID- 4217114 TI - [Obstructive myocardiopathy, Turner-Ullrich syndrome and von Recklinghausen's disease]. PMID- 4217115 TI - [Common types of neurofibromatosis. Elements of a mental syndrome (apropos of 5 cases]. PMID- 4217116 TI - [Longitudinally bracketed diaphysis]. PMID- 4217118 TI - [Heart diverticula in children: radiological aspects]. PMID- 4217117 TI - [The Laurence-Moon-Bardet-Biedl syndrome. Urographic signs]. PMID- 4217119 TI - [New technics for chronic parenteral feeding]. PMID- 4217120 TI - [Long term intestinal substitution in dogs]. PMID- 4217122 TI - [Arterial pedicles of mamillary bodies in the dog (Canis familiaris)]. PMID- 4217121 TI - The effect of practolol on circulatory response after sympathetic stimulation and on plasma growth hormone and insulin levels. PMID- 4217123 TI - Treatment of partial ruptures of the lateral ligament of the ankle in acute ankle sprains. PMID- 4217124 TI - The surgical treatment of injuries of the fibular collateral ligaments of the ankle. PMID- 4217125 TI - The mid-dermis graft - an experimental study. PMID- 4217126 TI - Vitamin B12 absorption after resection of ileum in childhood. PMID- 4217127 TI - Letter: effective thyroxine ratio in infants, children, and adolescents. PMID- 4217129 TI - Blood group antigens and antibodies in Nigeria. PMID- 4217128 TI - [Histochemical investigations of derman nevus cells. (Fluorescence histochemistry of Falck-Hillarp and enzyme histochemistry) (author's transl)]. PMID- 4217131 TI - Iron supplementation in Thai fish-sauce. PMID- 4217130 TI - Some further observations on the use of a continuous flow apparatus for the maintenance of schistosomes and blood protozoa in vitro. PMID- 4217132 TI - The effect of vasodilators on calcium kinetics in blood vessels. PMID- 4217133 TI - [Left ventricular telediastrolic pressure in the acute stage of myocardial infarction]. PMID- 4217134 TI - [Temporary cardio-circulatory mechanical assistance. Present results of a medical department of cardiologic resuscitation]. PMID- 4217135 TI - [Mid term results of Carpentier's reconstructive tricuspid annuloplasty. Apropos of 25 cases with postoperative catheterization]. PMID- 4217136 TI - [Restrictive type cardiac failure in primary hemochromatosis]. PMID- 4217137 TI - [Electrocardiogram in repeated infarction. Electrocardiographic aspects of initial infarction during a new localization in the opposite territory. Apropos of 95 cases with anatomical correlation]. PMID- 4217138 TI - [Mechanical systole of the left ventricle in myocardial infarction]. PMID- 4217139 TI - [Treatment of 13 cases of severe pulmonary embolism using streptokinase. Hemodynamics and angiopneumographic controls]. PMID- 4217140 TI - [Indication of temporary electrosystolic pacemaking in general surgery]. PMID- 4217141 TI - [Preservation of the ischemic myocardium by hypothermia. Biochemical and morphological study during extracorporeal circulation]. PMID- 4217143 TI - [Primary dissecting hematoma of the coronary artery media]. PMID- 4217142 TI - [Massive aortic insufficiency consecutive to an incomplete rupture of the suprasigmoidian aorta. Insertion of a Starr's valve]. PMID- 4217144 TI - Photorespiration in diatoms. The oxidation of glycolic acid in Thallassiosira pseudonana (Cyclotella nana). PMID- 4217145 TI - The pigments of Flexibacter elegans: novel and chemosystematically useful compounds. PMID- 4217146 TI - hepatitis-hepatis. PMID- 4217149 TI - The influence of pharmaca on the oxygen induced constriction of the human umbilical cord artery. PMID- 4217148 TI - [Pseudodiastrophic dwarfism. Study of 2 newborn sisters]. PMID- 4217147 TI - [The diversities of Phacomatosis (Hamartosis). Apropos of a case likely to represent a new syndrome]. PMID- 4217150 TI - Phytohemagglutinin-induced blastoid transformation of lymphocytes, skin tests and immunoglobulin levels in clinically advanced malignant lymphogranulomatosis. PMID- 4217151 TI - [Syndromes in psychiatric illnesses. A comparative investigation with two rating scales (IMPS and AMP-scale) (author's transl)]. PMID- 4217152 TI - [Mycobacterium. Strains isolated from patients with genito-urinary problems in Brasil (author's transl)]. PMID- 4217153 TI - [Microbiological aspects of the genital flora of bovines (author's transl)]. PMID- 4217154 TI - Influence of concentration, time, temperature and pH on the retention of chlorhexidine in the human oral cavity after mouth rinses. PMID- 4217155 TI - Collagen fibre bundles of the normal marginal g-ngiva in the marmoset. PMID- 4217156 TI - The use of amphotericin B to increase the selectivity of media used for isolating oral lactobacilli. PMID- 4217157 TI - Collagen breakdown in relation to tooth eruption and resorption in the dog. PMID- 4217158 TI - [The pathological significance of paraarticular ossifications after total hip replacements (author's transl)]. PMID- 4217159 TI - [Clinical results with arthrodesis of the ankle joint (author's transl)]. PMID- 4217160 TI - [Rupture of fibular collateral ligaments--diagnosis, surgical treatment, results (author's transl)]. PMID- 4217161 TI - [Weight-bearing capacity of the femoral head after experimental ischaemic necrosis of the epiphysis. I. Histological examination (author's transl)]. PMID- 4217162 TI - Vestibular sensory epithelia. PMID- 4217163 TI - [Anti-D antibodies after spontaneous abortion]. PMID- 4217164 TI - Electronmicroscopical findings of the spiral ganglion and the organ of Corti in guinea pigs using glutaraldehyde- and osmiumfixation with various fixation techniques (author's transl). PMID- 4217165 TI - Effect of composition of tris-based diluent on survival of boar spermatozoa following deep freezing. PMID- 4217166 TI - Some quantitative features of Drosophila sternite bristle patterns. PMID- 4217167 TI - trypsin extractable precipitating antigens of Leptospira interrogans (serotype Biflexa). PMID- 4217168 TI - Relative specificities of immunoglobulins reacting with axial filament antigens of Leptospira. PMID- 4217169 TI - The origin of antibody in intestinal secretion of sheep. PMID- 4217170 TI - A microtitre serum neutralization test for bovine ephemeral fever virus. PMID- 4217171 TI - Immunodeficiency and grouping with thyrogastric autoimmune disease in patients with chronic idiopathic thrombocytopenic purpura. PMID- 4217172 TI - Studies on equine herpesviruses. 5. Isolation and characterisation of slowly cytopathic equine herpesviruses in Queensland. PMID- 4217173 TI - Letter: Sarcoptes scabiei infestation of a koala (Phascolarctos cinereus), with probable human involvement. PMID- 4217174 TI - Vertebral angiography in bilateral VIII cranial nerve tumours. A report of a case. PMID- 4217175 TI - The alteration of aversive thresholds after chronic administration of two tranquilizing agents. PMID- 4217176 TI - Quantitative analysis of ciliary and contractile responses during habituation training in Spirostomum ambiguum. PMID- 4217177 TI - Ultrastructure of genetic activity in eukaryotic cells. PMID- 4217178 TI - Radio telemetry of blood flow and pressure measurements in untethered conscious animals. PMID- 4217179 TI - A selective system for a biochemical analysis of the lethal mutation l(2)me of Drosophila melanogaster. PMID- 4217180 TI - Nucleotide sequence divergence among DNA fractions of different syngens of Tetrahymena pyriformis. PMID- 4217182 TI - Analysis of the specific radioactivity of valine isolated from aminoacyl-transfer ribonucleic acid of rat liver. PMID- 4217181 TI - The specificity of chain interactions among immunoglobulins. Combinations of gamma chains with kappa chains of the same subgroup as in the parent immunoglobulin G. AB - 1. The specificity of combination of heavy and light chains from selected human immunoglobulins was examined in the light of greater structural information than in previous studies. Heavy (gamma) chains from immunoglobulin G (kappa) myeloma proteins were allowed to combine with their homologous light (kappa) chains or with other kappa chains of the same variable-region subgroup. The affinity of each such pairing was assessed by having the test kappa chain compete with a standard population of normal light chains. 2. There was a spread of affinities among the heavy-light pairings with the homologous pairings having an average affinity significantly higher than the heterologous pairings. 3. It follows that (a) the preference shown for homologous heavy-light pairings is not explicable simply in terms of the known subdivisions of the variable and constant regions of the chains, and (b) it is unlikely that those residues specifying the subgroups of kappa-chain variable regions have a predominant role in the formation of interchain bonds with the gamma-chain variable regions. PMID- 4217184 TI - Effect of dietary changes on the rates of synthesis and degradation of rat liver fatty acid synthetase. PMID- 4217183 TI - Disorders of lipid metabolism. PMID- 4217185 TI - Studies on the membranes of Bacilli. III. Disaggregation and reaggregation of the membrane components of Bacillus megaterium KM. PMID- 4217186 TI - Sympathetic receptor functions in liver damage. PMID- 4217187 TI - Primary drug resistant tuberculosis in Puerto Rico. PMID- 4217189 TI - [Changes in the rate of protein synthesis in the absence of RNA synthesis in Euglena gracilis]. PMID- 4217188 TI - [Editorial: Primary resistance to antitubercular drugs in Puerto Rico]. PMID- 4217190 TI - [Effect of Mg++ ion on 5-nucleotidase activity]. PMID- 4217191 TI - [Liberation of enzyme activities correlated with the utilization of exogenous AMP in the bathing medium of Bacillus cereus cells]. PMID- 4217192 TI - [Immunological determination of hemoglobin A2]. PMID- 4217193 TI - Protection of mice against syngeneic lymphomata: I. Use of antibodies. AB - Protection tests using passively administered antibody have been carried out using 2 mouse lymphomata. The classic model ("Gorer System") used alloantiserum which was absorbed in vivo to make it tumour specific before use. In order to provide a system suitable for our work, the model was changed by stepwise transitions to tumour specific immunoglobulin made from xenoantiserum absorbed in vitro, since such a procedure is also applicable to human patients. The time lapse used between challenge and treatment in the allo-system was generally +/- 2 h but in the xeno-system could be extended to + 18 h. The xenoantisera could not be absorbed in vivo but required 3 to 5 * 10(3) spleens per 100 ml serum to absorb in vitro to render them tumour specific. The protective antibody was in the IgG (not IgM) fraction of serum. Maximal tumour specific antibody (measured by in vivo protection) appeared after the third injection of rabbits for one lymphoma, but after the fifth for another. The sera were not cross-reactive among 3 lymphomata tested, of which 2 were of the same H-2 genotype. PMID- 4217194 TI - Protection of mice against syngeneic lymphomata: II. Collaboration between drugs and antibodies. AB - Rabbit anti-mouse tumour cell serum can be made tumour specific by absorption with normal mouse cells and in an in vivo protection test can be shown to have a measurable protective effect on mice against a given number of lethal doses of a lymphoma. Some drugs have been evaluated in this system. When drug treatment is combined with antibody treatment much greater protection can be obtained than when the same amounts of drug or antibody are used alone. It is preferable to administer drug before antibody and with the combined schedule it is possible in the test model to protect all mice from tumour growth, even allowing the tumour up to 48 h "get-away" time before starting treatment. PMID- 4217195 TI - [Microheterogenity of lamb fetuin]. PMID- 4217196 TI - [Primary structure of human B erythrocyte carbonic anhydrase. 3. Sequence of CNBr fragment I and III (residues 149-260)]. PMID- 4217197 TI - [Albumin synthesis during culture of human hepatic parenchyma]. PMID- 4217198 TI - [The two-component nature of human alpha-fetoprotein demonstrated by electrofocusing]. PMID- 4217199 TI - [High molecular protein antigens of burned skin, their fractionation and properties]. PMID- 4217200 TI - [Croynebacterium diphtheriae neuraminidase as a pathogenic factor with a spreading function]. PMID- 4217201 TI - [The effect of emotional overstimulation on the state of blood coagulation system indices in monkeys]. PMID- 4217202 TI - [Location of myocardial antigens by the immunofluroescent method]. PMID- 4217203 TI - [The mechanism of interaction between factor XII and surfaces possessing different physico-chemical properties]. PMID- 4217204 TI - Phencyclidine: pharmacology and toxicology. PMID- 4217205 TI - The American perspective. PMID- 4217206 TI - Acute and chronic biological false positive reactors to serological tests for syphilis. ABO blood groups and other investigations. PMID- 4217207 TI - Comparative assessment of microbiological methods for the diagnosis of gonorrhea in women. PMID- 4217208 TI - Treatment of gonorrhoea using a combination of intramuscular and oral ampicillin. PMID- 4217209 TI - Comparison of direct microscopy and culture in the diagnosis of trichomoniasis. PMID- 4217210 TI - Primary syphilis in the oral cavity. PMID- 4217211 TI - [Polyphenoloxidase activity extracted from horse melanoma]. PMID- 4217212 TI - [Isolation of soluble isoltyrosinases extracted from horse melanoma]. PMID- 4217213 TI - Effects of ethylenediaminetetraacetate (EDTA) on urinary excretion of hydroxyproline, calcium and phosphorus in the rat. PMID- 4217215 TI - Temperature-sensitive mutations in Drosophila melanogaster. XX. Lethality due to translocations. PMID- 4217214 TI - Inorganic pyrophosphatase in mineralizing hamster molars. IV. Modification of the inhibition of EDTA, diphosphonates and L-ascorbic acid by Zn2+ and C02+. PMID- 4217216 TI - Is primary drug-resistance to major antituberculous agents increasing? PMID- 4217217 TI - A new antitumor agent, (alphas, 4s, 5r)-alpha-amino-3-chloro-4-hydroxy-4,5 dihydro-5-isoxazoleacetic acid (NSC-176324): preliminary evaluation against L 1210 mouse leukemia in vivo. PMID- 4217218 TI - Ultrastructural localization of calcium in the pigeon papillary muscle as demonstrated by cytochemical studies and x-ray microanalysis. PMID- 4217220 TI - [Effects of TEA on membrane rectification of the crab striated muscle fiber studied in voltage clamp conditions in the presence of chloride ions]. PMID- 4217219 TI - [Influence of the microbial flora on the functional results of tympanoplasties in the tropical areas]. PMID- 4217221 TI - [Effect of lactation of pre-ovulatory LH discharge induced by synthetic LRF injection in the ewe during the seasonal anestrus period]. PMID- 4217222 TI - [Variation of the oxide layer of a Domal magnesium anode used in an implantable bioelectric battery]. PMID- 4217223 TI - [Varieties of enterobacteria, especially colibacilli, and their geographic distribution]. PMID- 4217224 TI - [The hematologic pattern during larval development and metamorphosis in Triturus cristatus]. PMID- 4217225 TI - [Study of the phylogeny of related species--horse, donkey and mule--by a labeling technic]. PMID- 4217226 TI - [Ultrastructure of the human chromosome: chromosomal fiber and chromomere]. PMID- 4217227 TI - [Persistence of circadian rhythms of wakefulness-sleep alternation and feeding behavior in a 20-year-old man during his underground isolation, with and without a clock]. PMID- 4217228 TI - [Utilization of ethyl alcohol in the energy metabolism of an insect: influence on the longevity of Drosophila melanogaster adults]. PMID- 4217230 TI - [Effects of the preventive or differed use of actinomycin D on the regeneration of young and adult Planaria]. PMID- 4217229 TI - [Cyto-immunologic study of variations in gonadotropic cells and prolactin cells during the annual sexual cycle in the anterior pituitary of the female fox]. PMID- 4217231 TI - [LH-RH- TRH test and LH-RH therapy in anorexia nervosa and amenorrhea due to reduced food intake]. PMID- 4217232 TI - [Reaction of prolactin to TRH in various diseases]. PMID- 4217233 TI - [Hemagglutination reaction and alpha-fetoprotein. Comparison with single radial immunodiffusion and its clinical significance]. PMID- 4217234 TI - Fatal Bacillus cereus pneumonia and sepsis in a child with cancer. PMID- 4217235 TI - Normal immunoglobulin levels in children who have recovered from meningococcal meningitis. PMID- 4217236 TI - Prepubescent gonococcal vulvovaginitis. PMID- 4217237 TI - Vertebral osteomyelitis in a young infant. PMID- 4217238 TI - Laboratory tests for the assessment of nutritional status. PMID- 4217239 TI - Erwinia infections in man. PMID- 4217240 TI - A double-blind evaluation of 'Hydergine' and placebo in the treatment of patients with organic brain syndrome and cerebral arteriosclerosis in a nursing home. PMID- 4217241 TI - A comparison of the onset of bronchodilator activity of metaproterenol and isoproterenol aerosols. PMID- 4217242 TI - "Immunostaging" as a guideline to immunotherapy in malignancy. PMID- 4217243 TI - Prazosin in hypertension: a double-blind evaluation with methyldopa and placebo. PMID- 4217245 TI - Treatment of essential hypertension with pindolol and clopamide: problems arising from a combined beta blocker and diuretic therapy. PMID- 4217244 TI - The effects of metolazone in the long-term treatment of essential hypertension. PMID- 4217246 TI - Local treatment of psoriasis and eczema with betamethasone-17,21-dipropionate (Diproderm cream): a double-blind comparsion with fluocortolone caproate, fluocortolone pivalate (Ultralanum cream). PMID- 4217248 TI - Sulpiride: a chemotherapy for post-traumatic vertigo syndromes. PMID- 4217247 TI - A double-blind comparison of a tetracycline-novobiocin combination antibiotic and tetracycline alone in common infections. PMID- 4217249 TI - Double-blind comparison of alophen with its components for cathartic effects. PMID- 4217250 TI - Viloxiazine--a new antidepressant. PMID- 4217251 TI - Loxapine succinate: a controlled double-blind study in schizophrenia. PMID- 4217252 TI - Assessment of antipsychotic activity of a butyrophenone analogue, lenperone (AHR 2277). PMID- 4217254 TI - [Correlation between allergy and chronic bronchitis. A preliminary report]. PMID- 4217253 TI - Pilot open-label study on U-28,774, in anxious in-patients. PMID- 4217255 TI - [Treatment of chronic cor pulmonale during the early stage or remission. Report of 100 cases]. PMID- 4217256 TI - [Treatment of chronic bronchitis with salmonella typhi lipopolysaccharide. Report of 149 cases]. PMID- 4217257 TI - [Nebulized inhalation. Measurement of aerosol particles and their distribution in the respiratory tract]. PMID- 4217258 TI - [Left anterior hemiblock]. PMID- 4217259 TI - [Isoproterenol in the treatment of fulminating meningococcemia in children complicated by shock. An analysis of 181 cases]. PMID- 4217260 TI - [Corticosteroids in the treatment of severe icteric hepatitis. Clincal analysis of 23 cases]. PMID- 4217261 TI - [Surgical treatment of chronic empyema]. PMID- 4217262 TI - [Correlation between the pattern of the arteries at the base of the brain and hypertensive cerebral hemorrhage]. PMID- 4217263 TI - [Immunoglobulins and chronic bronchitis]. PMID- 4217264 TI - [Clinicopathological conference. No. 22. Pain at the lower left abdomen, emaciation, paralysis and a tumor of the dorsal wall of the vagina]. PMID- 4217265 TI - Development of the macronuclear anlage in the ciliate Chilodonella uncinate. I. Morphological and cytophotometric studies on the evolution of DNA. PMID- 4217266 TI - [Penetration of Bacillus subtilis H3-DNA into isolated protoplasts of Nicotiana tabacum L. cells]. PMID- 4217267 TI - [Letter: Euthyroid peripheral values of thyroid hormones and TRH-refractory suppression of TSH]. PMID- 4217268 TI - [Clinico-diagnostic importance of surface-markers of human T- and B-lymphocytes]. PMID- 4217269 TI - [Radiotherapy and ECRF 159 (NCS 129943) in the treatment of inoperable soft tissue sarcoma (author's transl)]. PMID- 4217270 TI - [Pathophysiology of the triiodothyronine production]. PMID- 4217271 TI - [Treatment of epilepsy]. PMID- 4217272 TI - [Epilepsy, criminality and mental disorders]. PMID- 4217273 TI - Thyroid function of the aged as viewed from the pituitary-thyroid system. PMID- 4217274 TI - Serum thyrotropin response to thyrotropin releasing hormone and the concentration of thyroid hormone in patients with hyperfuncting thyroid nodule. PMID- 4217275 TI - Effect of somatostatin (growth hormone inhibiting factor: GIF) on TRH-induced TSH release in rats. PMID- 4217276 TI - The preparation and characterization of two forms of bovine galactosyl transferase. PMID- 4217278 TI - Reaction mechanism of D-galactose dehydrogenases from Pseudomonas saccharophila and Pseudomonas fluorescens. Formation and rearrangemnt of aldono-1,5-lactones. PMID- 4217277 TI - Glycosphingolipids and glycoproteins in the wild-type and in non-aggregating mutant of Dictyostelium discoideum. PMID- 4217279 TI - Effects of nitroglycerin on myocardial transmural differences in blood flow, oxygen and carbon dioxide tensions in normal and ischemic canine hearts. PMID- 4217280 TI - Effect of two different climates on severely burned rats infected with Pseudomonas aeruginosa. PMID- 4217281 TI - Hemoglobin synthesis inhibiting factor (HSIF). Chemical and biological characterizations. PMID- 4217282 TI - [The diurnal rhythm of biogenic amines in man under normal conditions and in hypoxia]. PMID- 4217283 TI - Pheromones in primate reproduction and social behavior. PMID- 4217284 TI - Proceedings: Solubilization of adenylate cyclase of rat corpora lutes. PMID- 4217285 TI - Effect of furylfuramide, a potent mutagen, on reproduction and malformation. PMID- 4217286 TI - Physiology and pharmacology of PGs in parturition. PMID- 4217287 TI - Transplacental haemorrhage in abortions. PMID- 4217288 TI - Protein malnutrition in the rat: its effects on maternal behavior and pup development. PMID- 4217289 TI - Experiences in the clinical management of amniotic alpha-fetoprotein estimations. PMID- 4217290 TI - Characterization of Chinese hamsters by metabolic balance, glucose tolerance and insulin secretion. PMID- 4217291 TI - The diabetic Chinese hamster: in vitro insulin and glucagon release; the ""chemical diabetic";; and the effect of diet on ketonuria. PMID- 4217292 TI - Morphological characterization of membrane systems in A- and B-cells of the Chinese hamster. PMID- 4217293 TI - Segmental demyelination in the distal peripheral nerves of chronically diabetic Chinese hamsters. PMID- 4217294 TI - The polyol pathway for glucose metabolism in tissues from normal, diabetic, and ketotic Chinese hamsters. PMID- 4217295 TI - Hepatic and renal protein synthesis in normal, diabetic and ketotic Chinese hamsters. PMID- 4217296 TI - Effect of diet limitation on the development of diabetes in prediabetic Chinese hamsters. PMID- 4217297 TI - Morphologic abnormalities observed in retina, pancreas and kidney of diabetic Chinese hamsters. PMID- 4217298 TI - Epidemiology of Chinese hamsters and preliminary evidence for genetic heterogeneity of diabetes. PMID- 4217299 TI - Aortic glucose metabolism in the diabetic Chinese hamster. PMID- 4217300 TI - Characterization of diabetes mellitus in South African hamsters (Mystromys albicaudatus). PMID- 4217301 TI - [Importance of C3 in the diagnosis of acute glomerulonephritis in children]. PMID- 4217302 TI - [Immunoproliferative diseases. Immunochemical classification and presentation of a case of micromolecular myleoma]. PMID- 4217303 TI - Effects of population size and selection intensity on responses to disruptive selection in Drosophila melangaster. AB - Disruptive selection for sternopleural bristle number with opportunity for random mating was done in the four treatment combinations of two population sizes (40 pairs and 8 pairs of selected parents) and two selection intensities (1 in 40 and 1 in 2). In each generation, matings among selected parents were observed in a mating chamber, and progeny collected separately from each female parent. In the high number, high selection intensity treatment, divergence between the high and low parts ceased about generation 11. The isolation index increased rapidly to generation 3, but then fluctuated to termination of the population at generation 17. The overall isolation index was significant, indicating a real tendency to assortative mating. The failure of the isolation index to increase after generation 3 was attributed to lower average mating fitness of high males (due to inbreeding) and reduced receptivity of low females (due to a homozygous lethal gene with a large effect on sternopleural bristle number in heterozygotes). In the two low number treatments, isolation indices fluctuated from generation to generation with no obvious trends, and none of the overall isolation indices were significantly different from zero. The high number, low selection intensity treatment showed very little divergence, and one of the replicates showed, in contrast with expectation and the high number, high selection intensity treatment, a significant tendency to disassortative mating. Intense disruptive selection may lead to assortative mating. PMID- 4217304 TI - Steroid induction of the mRNA for hepatic tryptophan oxygenase. PMID- 4217305 TI - Inhibitors of mammalian protein synthesis. PMID- 4217306 TI - [Behavior of urea, alpha-amino nitrogen and free amino acids in infants with hypertrophic pylorostenosis]. PMID- 4217307 TI - Pharmacology of Sintamil metabolites. PMID- 4217309 TI - Effect of mutation on the amylolytic and proteolytic activity of Bacillus subtilis isolated from domestic waste water. PMID- 4217308 TI - Electron microscopic autoradiographic studies on polytene nuclei of Drosophila melanogaster: Part I. Replication and its relationship with nuclear membrane. PMID- 4217310 TI - Immunoglobulins in health and disease. II. IgE concentrations in the sera of patients with bronchial asthma. PMID- 4217311 TI - Peroxidase-dependent oxidation of tyrosine to melanin in leucodermic vitiligenous skin. PMID- 4217312 TI - Some anthropologic investigations of interest to oral surgeons. PMID- 4217313 TI - Surgical and orthodontic treatment of cleidocranial dysostosis. PMID- 4217315 TI - Use of propylic ester of p-hydroxy-benzoic acid after removal of impacted mandibular third molars. PMID- 4217314 TI - Results of apicoectomy of maxillary canines, premolars and molars with special reference to oroantral communication as a prognostic factor. PMID- 4217316 TI - Experimental reconstruction of the mandibular joint. PMID- 4217317 TI - A radiographic and clinical follow-up study of 150 oroantral communications. PMID- 4217318 TI - Evaluation of carticaine - a new local analgesic. PMID- 4217319 TI - Cilnical experiences in oral surgery using a new self-aspirating injection system. PMID- 4217321 TI - A case of gigantiform cementoma. PMID- 4217320 TI - The effect of mucin-containing artificial saliva on severe xerostomia. PMID- 4217322 TI - Report on an oral, pigmented, squamous cell carcinoma. PMID- 4217323 TI - Some analyses of exsheathing fluid from infective Haemonchus contortus larvae from Ontario. PMID- 4217324 TI - Evidence of a rat-snake life cycle for Sarcocystis. PMID- 4217325 TI - Stimultaneous determination of effective renal plasma flow and glomerular filtration rate by the "single shot" method. PMID- 4217326 TI - Enterovirus etiology of the 1970 Singapore epidemic of acute conjunctivitis. PMID- 4217327 TI - [Anesthesia in liver, gallbladder and biliary tract surgery]. PMID- 4217328 TI - [Secondary reconstruction following biliary tract injuries. Results and failures]. PMID- 4217329 TI - [Surgical treatment of liver hydatid cysts. Apropos of a series of 381 cases]. PMID- 4217330 TI - Genetic tests on Drosophila melanogaster with polychlorinated biphenyls (PCB). PMID- 4217331 TI - Changes of zeste phenotype induced by autosomal mutations in Drosophila melanogaster. PMID- 4217332 TI - Stabilising selection in constant and fluctuating environments. PMID- 4217333 TI - Phenotypic observations on modification of position-effect variegation in Drosophila melanogaster. PMID- 4217334 TI - Studies on the nature and function of polygenic loci in Drosophila. I. Comparison of genomes from selection lines. PMID- 4217335 TI - Studies on the nature and function of polygenic loci in Drosophila. II. The subthreshold wing vein pattern revealed in selection experiments. PMID- 4217336 TI - The mechanism of metal binding to glutaraldehyde-fixed noradrenaline-storing adrenomedullary granules. PMID- 4217337 TI - Immunocytochemical demonstration of intestinal alkaline phosphatase. PMID- 4217338 TI - [Necrotizing external otitis.-A clinical and therapeutic study (author's transl)]. PMID- 4217339 TI - Proceedings: Numbers of neurons through full depth of neocortex. PMID- 4217341 TI - The antagonistic effects of antimitotic agents on contraction and re-extension in the ciliate Spirostomum ambiguum. PMID- 4217340 TI - Evidence for the association of RNA with the ciliary basal bodies of Tetrahymena. PMID- 4217342 TI - Limpet haemocytes. III. Effects of cytochalasin B and colchicine on cell spreading and aggregation. PMID- 4217343 TI - Penicillin control of swelling and pain after periodontal osseous surgery. PMID- 4217344 TI - Schizophrenic response to affectivity in word definition. PMID- 4217345 TI - Tonsillolith and elongated styloid. PMID- 4217346 TI - [Quantitative estimation of immunoglobulins (IgG, IgM and IgA) in human gingival tissue with periodontal disease (author's transl)]. PMID- 4217347 TI - A high frequency of fertilization in premature and mature coelomic toad eggs after enzymic removal removal removal of vitelline membrane. PMID- 4217348 TI - Intracellular calcium binding and release in frog heart. AB - The capacities and affinities of intracellular calcium-binding sites have been studied in frog ventricles, in which the concentration of Ca(++) in the sarcoplasm can be controlled as a result of treatment with EDTA. The total calcium content of calcium-depleted and nondepleted muscles at rest and muscles generating considerable tension was 0.8, 1.4, and 5.4 micromol/g of muscle, respectively. Net movement of calcium into or out of the cells occurred without change in tension when the sarcoplasmic concentration of Ca(++) was either of two values, less than 10(-7) M or approximately 5 x 10(-7) M. These data can be explained by the presence of two groups of intracellular calcium sinks which compete with the contractile proteins, one with a capacity of about 0.6 micromol/g and an affinity constant greater than 10(7) M(-1) and a second with a capacity of 4.0 micromol/g and an affinity constant of about 2 x 10(6) M(-1). The higher affinity calcium is released by anoxia, oligomycin, or abrupt changes in sarcoplasmic Ca(++). Muscles soaked in Sr-Ringer's contain electron densities in the sarcoplasmic reticulum and to a lesser extent in the mitochondria. PMID- 4217349 TI - Immunochemical identification of a new molecular form of acid phosphatase of host origin arising during infection of potato tubers by Phytophthora erythroseptica Pethybr. PMID- 4217350 TI - The properties and host range of male-specific bacteriophages of Pseudomonas aeruginosa. PMID- 4217351 TI - Nitrification by aflatoxigenic strains of Aspergillus flavus and Aspergillus parasiticus. PMID- 4217352 TI - Establishment of a limited rumen flora in gnotobiotic lambs fed on a roughage diet. PMID- 4217353 TI - The metabolism of starch, glucose, amino acids, purines, pyrimidines and bacteria by three Epidinium spp. isolated from the rumen. PMID- 4217354 TI - The utilization of Bacillus megaterium and the release of a lytic enzyme by three Epidinium spp. isolated from the rumen. PMID- 4217355 TI - The metabolism of Epidinium ecaudatum caudatum and Entodinium caudatum as shown by autoradiography in the electron microscope. PMID- 4217356 TI - A co-operative numerical analysis of cultures considered to belong to the 'rhodochrous' taxon. PMID- 4217357 TI - Mucopeptide synthesis by rod mutants of Bacillus subtilis. PMID- 4217358 TI - Temperature sensitivity of sporulation in Bacillus cereus. PMID- 4217359 TI - Prostaglandins and the anti-inflammatory activity of a human plasma fraction in carrageenan-induced paw oedema in the rat. PMID- 4217360 TI - Ionic relations and electrical properties of isolated oocytes of Bufo bufo with special reference to removal of extracellular chloride. AB - 1. The efflux rate coefficients of sodium, potassium and chloride from immature oocytes of the toad Bufo bufo have been measured and found to be respectively, 0.0069, 0.0023 and 0.0034 min(-1).2. Replacement of external chloride by sulphate resulted in a fall in chloride efflux of about 50%. This has been interpreted in terms of exchange diffusion.3. The membrane conductance has been measured and found to be 0.14 x 10(-3) mhos cm(-2) in good agreement with the value calculated from the flux data, 0.12 x 10(-3) mhos cm(-2), after taking account of the chloride exchange diffusion fraction. PMID- 4217362 TI - [Proceedings: Chronic study of dopamine fiberation by the caudate nucleus in the nonanesthetized and free monkey]. PMID- 4217361 TI - The effect of holding potential on the asymmetry currents in squid gaint axons. AB - 1. Asymmetry currents were recorded from intracellularly perfused squid axons subjected to an equal number of exactly equal positive and negative voltage clamp pulses. The asymmetry currents consisted of an on-response at the beginning of the pulses and an off-response at the end of the pulses.2. The asymmetry currents were markedly reduced by 30 mM glutaraldehyde applied internally.3. Clamp pulses of varying height, superimposed on a holding potential of - 80 to - 100 mV, were used to study the voltage and time dependence of the asymmetry current. The magnitude of the on- and off-response increased with increasing pulse height along a sigmoid curve. The time constants of the on- and off-response depended on the potential during the depolarizing pulses; the time constant of the on response had a maximum at an internal potential of - 12 mV, the time constant of the off-response was largest at positive internal potentials.4. Holding the membrane at a potential of - 80 to - 100 mV for several minutes led to a slow increase of the size of the asymmetry current.5. Changing the holding potential from - 80 or - 100 mV to a less negative potential caused a decrease of the asymmetry current. At holding potentials less negative than - 65 or - 60 mV the asymmetry current reversed its sign: the transient current at the beginning of the pulses turned into an inward current and the transient current at the end of the pulses became outward. No inactivation of the asymmetry current was seen in the range of holding potentials studied (V < - 3 mV).6. The results are generally consistent with the idea that the asymmetry currents are in some way related to the opening and closing of the Na gates; they suggest, however, that the asymmetrical charge movement does not simply reflect the voltage and time dependence of the m system. PMID- 4217363 TI - [Proceedings: Unitary activity in the monkey motor cortex during movement of a deafferent limb]. PMID- 4217364 TI - [Proceedings: Cerebellum pathophysiology in the monkey. 1. Origin of afferent spinal nerves and cerebello-pontile nerves]. PMID- 4217365 TI - [Proceedings: Pathophysiology cerebellum in the monkey. 2. Motor deficit combined with lesions of cerebellar structures]. PMID- 4217366 TI - Haemogregarina pseudemydis n. sp. (Apicomplexa: Haemogregarinidae) and Pirhemocyton chelonarum n. sp. in turtles from Louisiana. PMID- 4217367 TI - Cryptosporidium anserinum sp. n. (Sporozoa) in a domestic goose Anser anser L., from Iowa. PMID- 4217368 TI - Fine structure of the cyst and some sporulation stages of Ichthyosporidium (Microsporida). PMID- 4217369 TI - Terebrospira chattoni sp. n., a parasite of the endocuticle of the shrimp Palaemonetes pugio Holthuis. PMID- 4217370 TI - Diplodinium flabellum: occurrence and numbers in the rumen of sheep with a description of two new subspecies. PMID- 4217371 TI - Ultrastructure of symbiotic bacteria in normal and antibiotic-treated Blastocrithidia culicis and Crithidia oncopelti. PMID- 4217372 TI - Besnoitia jellisoni in macrophages and cysts from experimentally infected laboratory mice. PMID- 4217373 TI - Ultrastructural localization of acid phosphatase in starved Tokophrya infusionum. PMID- 4217374 TI - Studies of membrane formation in Tetrahymena pyriformis. VIII. On the origin of membranes surrounding food vacuoles. PMID- 4217375 TI - Beta-oxidation in glyoxysomes from Euglena. PMID- 4217376 TI - Isolation and characterization of kinetoplast DNA networks and minicircles from Crithidia fasciculata. PMID- 4217377 TI - Isolation of kinetoplast-mitochondrial complexes from Leishmania tarentolae. PMID- 4217378 TI - Immunogenicity of the delta-haemolysin of Staphylococcus aureus. PMID- 4217379 TI - Candida serology in open-heart surgery. PMID- 4217381 TI - Rapid group and species identification of enterococci by means of tests with pooled phages. PMID- 4217380 TI - Antibiotic-resistant gram-negative bacilli in the faeces of neonates. PMID- 4217382 TI - Immunoglobulin levels as related to age in nonhuman primates in captivity. I. Chimpanzees. PMID- 4217383 TI - Immunoglobulin levels as related to age in nonhuman primates in captivity. II. Rhesus monkeys. PMID- 4217384 TI - Restraining chair and face mask for inhalation toxicology studies in primates. PMID- 4217385 TI - Cutis verticis gyrata in a Chinese mental defective. PMID- 4217386 TI - Letter to editor: Subunit arrangements in bacterial flagella. PMID- 4217387 TI - A study of the histidine residues of human carbonic anhydrase B using 270 MHz proton magnetic resonance. PMID- 4217388 TI - The effects of fusidic acid on growth, ribosome synthesis and RNA metabolism in Escherichia coli. PMID- 4217389 TI - Infant malnutrition in Africa: the role of artificial milk feeds. PMID- 4217390 TI - Measuring the recovery rates of malnourished children from their weight-gains. Part I: review of existing methods. PMID- 4217391 TI - Measuring the recovery rates of malnourished children from their weight-gains. Part II: discussion of a new technique. PMID- 4217392 TI - [Metabolism of corticoids]. PMID- 4217393 TI - [Clinicopathological study of serum alpha 2 H S glycoprotein]. PMID- 4217394 TI - [Macroglobulinemia in the aged]. PMID- 4217395 TI - [Frequency of macroglobulinemia and its clinicopathological evaluation]. PMID- 4217396 TI - [Evaluation of serum and urinary uric acid analysis by NaCO3-urea method and EDTA hydrazine method]. PMID- 4217397 TI - [Evaluation of the immunological analysis of thymol and zinc sulfate turbidity reactions with the serum]. PMID- 4217398 TI - [Autoanalysis of serum immunoproteins (1)]. PMID- 4217399 TI - [Case of primary macroglobulinemia with marked hyperviscosity]. PMID- 4217400 TI - [Case of von Recklinghausen's disease with marked hypoproteinemia]. PMID- 4217402 TI - [Serotyping of Pseudomonas aeruginosa isolated in the last 2 years]. PMID- 4217401 TI - [Radioimmunoassay of thyrotropin-releasing hormone]. PMID- 4217403 TI - [Isolation of Listeria monocytogenes in a case of meningitis in a newborn infant (with special reference to bacteriological tests)]. PMID- 4217404 TI - Studies on the modification of the live AIK measles vaccine. I. Adaptation of the further attenuated AIK measles virus (the strain AIK-L33) to chick embryo cells. PMID- 4217405 TI - Protein composition of cell and forespore membranes of Bacillus subtilis. PMID- 4217407 TI - Unusual fracture and orthopedic problems. PMID- 4217409 TI - [Parenteral pre- and postoperative treatment of patients with intestinal fistulas (author's transl)]. PMID- 4217408 TI - [Indications for long term treatment of ventricular arrhythmias]. PMID- 4217406 TI - [Pherormones]. PMID- 4217410 TI - [Self-inflicted complications in intensive therapy (author's transl)]. PMID- 4217411 TI - [Construction of hospitals and hospital infection (author's transl)]. PMID- 4217412 TI - Antimicrobial activity of cultured plant cells and tissues. PMID- 4217413 TI - Hydrophobic chromatography. PMID- 4217414 TI - Affinity density perturbation. PMID- 4217415 TI - Pteroyllysine-agarose in the purification of dihydrofolate reductase. PMID- 4217416 TI - Group-specific separation of glycoproteins. PMID- 4217417 TI - Isolation of beta-galactosidase by chromatography. PMID- 4217418 TI - Alpha-lactalbumin-agarose. A specific adsorbent for a galactosyltransferase. PMID- 4217419 TI - Use of thyroxine in affinity chromatography. PMID- 4217420 TI - Covalent affinity chromatography of penicillin-binding components from bacterial membranes. PMID- 4217421 TI - Affinity chromatography of thermolysin and other neutral metalloendopeptidases. PMID- 4217422 TI - Purification of thymidylate synthetase with 2'-deoxyuridylate-agarose. PMID- 4217423 TI - [Concentration of several polyvalent metals in blue-green algae]. PMID- 4217424 TI - [Fine structure of the expospores of the non-sulfur purple bacteria Rhodomicrobium vannielii]. PMID- 4217425 TI - Editorial: The hunger striker. PMID- 4217426 TI - [Study of the antibacterial effect of organs and tissues of the tick Hyalomma asiaticum (Ixodidae)]. PMID- 4217427 TI - Physical aspects of supervoltage x-ray therapy. PMID- 4217428 TI - [Diagnosis and therapy of osteoporosis (author's transl)]. PMID- 4217429 TI - [The acute hypercalcemic crisis in primary hyperparathyroidism (author's transl)]. PMID- 4217430 TI - [Intrahepatic cholestasis of pregnancy (author's transl)]. PMID- 4217431 TI - Effects of dexamthasone and secobarbital on the pituitary response to thryotropin releasing hormone (TRH) in man: synergistic inhibition of thyrotropin (TSH) release. PMID- 4217432 TI - [Parenteral protein hyperalimentation. Application in surgery]. PMID- 4217433 TI - [Various problems of parenteral hyperalimentation]. PMID- 4217434 TI - [Respiratory manifestations in Waldenstrom's macroglobulinemia. Apropos of 5 cases]. PMID- 4217435 TI - Gentamicin by intravenous bolus injection. PMID- 4217436 TI - Chemotherapy of malignant mesothelioma. PMID- 4217438 TI - Chemoprophylaxis of bladder cancer recurrence: immunological aspects. PMID- 4217439 TI - [Plistophora tabani sp. n. (Microsporidia: Nosematidae), a parasite of gadfly larvae]. PMID- 4217437 TI - The diagnosis of subclinical mastitis in lactating cows: a comparison of cytological methods and a monovalent radial immunodiffusion test. PMID- 4217440 TI - [Clinical interpretation of cerebral symptoms in rheumatoid arthritis in a 16 year-old patient]. PMID- 4217441 TI - [Radioisotope methods of renal examination in pediatrics]. PMID- 4217442 TI - Residues of organochlorine insecticides and PCBs in samples of Norwegian butter 1972. PMID- 4217443 TI - [Pseudomonas aeruginosa. I. Occurrence in animals and man (author's transl)]. PMID- 4217444 TI - [The occurrence of Sarcocystis miescheriana in a stock of bacon pigs. An investigation of the frequency of infection during a year (author's transl)]. PMID- 4217445 TI - Membrane attachment of the chromosome in Bacillus subtilis mutants temperature sensitive in DNA replication. AB - We have examined three mutants of Bacillussubtilis temperature sensitive in DNA initiation and one temperature sensitive in DNA elongation, in order to investigate whether these lesions can cause or can result in a detachment of the membrane-bound chromosomal region. Our results argue against any effect of the mutations examined on the association between the chromosome and the membrane. PMID- 4217447 TI - [Laboratory animals in virologic studies and their naturally occurring viral infections]. PMID- 4217446 TI - [Effect of cromolyne on allergen inhalation tests in occupational asthma of bakers (author's transl)]. PMID- 4217448 TI - Radiotherapy. PMID- 4217449 TI - Acute barbiturate poisoning in young epileptics. PMID- 4217450 TI - [Proteolytic enzyme preparations from Pseudomonas aeruginosa grown on hydrocarbons]. PMID- 4217451 TI - [The relationship between the concentration of protein breakdown products in the culture media of several lactic acid streptococci and the quality of cheese produced with their use]. PMID- 4217452 TI - [Isolation of brewer's yeast invertase using enzyme preparations from actinomyces cellulosae]. PMID- 4217455 TI - The use of nuclear track detectors in the design of neutron collimators and scatterers. PMID- 4217453 TI - [Age-ralated characteristics of the metabolism of thyroid hormones and of the tissue sensitivity to them]. PMID- 4217454 TI - Accuracy of measurements of potassium content of monkeys by in vivo body counting as compared to chemical analysis. PMID- 4217456 TI - [Change in drug resistance of Mycobacterium tuberculosis in experimental studies]. PMID- 4217457 TI - A kinetic study on inorganic polyphosphate glucokinase from Mycobacterium tuberculosis H37RA. PMID- 4217458 TI - The comparison of thyrotropin releasing hormone, luteinising hormone-releasing hormone and placebo in depressive patients using a double-blind cross-over technique. PMID- 4217459 TI - Sex and long-term care. PMID- 4217460 TI - [Induction by gamma-radiation of ligase-specific breaks in bacterial DNA in vivo]. PMID- 4217461 TI - Thio-tepa and endoxan in combined treatment of breast cancer (cooperative trial). PMID- 4217462 TI - [Immunoglobulins, autoantibodies and Australia antigen in chronic hepatitis]. PMID- 4217463 TI - [Behavior of the 3rd components of the (beta 1C-beta 1A globulin) complement in various nephropathies]. PMID- 4217464 TI - [Rheo-encephalographic studies in children in normal and pathological conditions (preliminary observations)]. PMID- 4217465 TI - [Results of prolonged treatment of Parkinson's disease with the L-dopa benserazide combination]. PMID- 4217466 TI - Tobramycin treatment of pseudomonas aeruginosa infections in cystic fibrosis. PMID- 4217467 TI - Results of faecal examinations with special regard to vibrios in tourists returning from the same area as a verified case of cholera. PMID- 4217468 TI - Meningococcemia due to neisseria meningitidis serogroup D. PMID- 4217469 TI - [Recklinghausen's disease (neurofibromatosis) and pregnancy]. PMID- 4217470 TI - In vitro assay of malignant transformation by the oncogenic adenovirus SA7. PMID- 4217471 TI - The presence of Capillaria hepatica (Bancroft, 1893) Travassos, 1915 in a vervet monkey Cercopithecus aethiops. PMID- 4217472 TI - Pattern of biochemical and immune recovery in protein calorie malnutrition. PMID- 4217473 TI - The role of releasing hormones in the diagnosis of hypopituitarism. An analysis of 9 patients. PMID- 4217474 TI - Oesophageal motor dysfunction in patients with diverticula of the mid-thoracic oesophagus. PMID- 4217475 TI - Fibrinogen-fibrin-related antigen pattern in human blood. Differences between plasma and serum from pateints with disseminated intravascular coagulation. PMID- 4217476 TI - Rapid detection and quantitation of precipitating streptokinase-antibodies. PMID- 4217477 TI - Indirect measruement of streptokinase concentration in the plasma of patients undergoing fibrinolytic treatment. PMID- 4217478 TI - Long-term effects of ionizing radiation on drosophila midgut mitochondria. PMID- 4217479 TI - Dose distribution measurements in electron lens therapy with a 45 MeV betatron. PMID- 4217480 TI - [The effect of tricarboxylic acid cycle "carboxyline", acetate and acids on ketogenesis in rabbits with alloxan diabetes]. PMID- 4217481 TI - [Referral problems in long-term medical care]. PMID- 4217482 TI - [Polychlorinated biphenyls (PCB) in blood samples from 9 printers from Copenhagen]. PMID- 4217483 TI - The treatment of peritonitis in patients with chronic indwelling catheters. PMID- 4217485 TI - Serum middle molecule levels in uremia during long term intermittent hemoperfusions with the acac (coated charcoal) microcapsule artificial kidney. PMID- 4217484 TI - A compact portable prosthesis for total parenteral nutrition (t.p.n.): ambulatory parenteral feeding in the hospital and home. PMID- 4217486 TI - [Our veterinary medicine and veterinary sciences in the COMECON]. PMID- 4217487 TI - [Immunization of cattle against Q fever]. PMID- 4217488 TI - [Utilization of glucose and changes in the concentration of volatile fatty acids in kids during the 1st 5 months of life]. PMID- 4217489 TI - [Effect of synthetic LH-RH and L-Dopa on the level of LH in anoestral sheep]. PMID- 4217490 TI - [Effect of low temperature on the course of the growth curve in strains of Staphylococcus aureus]. PMID- 4217491 TI - [Xylazine and ketamine hydrochloride anesthesia in cats]. PMID- 4217492 TI - [25 years of socialist agriculture in CSSR (Czechoslovakia)]. PMID- 4217493 TI - [Decrease in the production of milk and its main components in the cases of subclinical mastitis in dairy cows]. PMID- 4217494 TI - [Q fever in the southern part of Western Slovakia]. PMID- 4217495 TI - [Locomotor system diseases in bulls kept in a large-scale fattening houses with slatted floors]. PMID- 4217496 TI - [Preventive effectiveness of the Spofa preparations with carbo adsorbens in the herds affected by diarrhea in the newborn calves]. PMID- 4217497 TI - Lankesterella from an East African crowned crane Balearica pavonina gibbericeps. PMID- 4217498 TI - Swine vesicular disease: a serological vurvey of pigs presented for slaughter. PMID- 4217499 TI - Placental structure and transmission of maternal immunity. PMID- 4217500 TI - Vaccinal immunity to Marek's disease in bursectomised chickens. PMID- 4217501 TI - [Cytological method of evaluating preparations in nosematosis in bees]. PMID- 4217502 TI - [The isoenzyme spectrum of erythrocyte carboanhydrase in dogs with acute renal insufficiency]. PMID- 4217504 TI - [Investigations of conjugated bilirubinoids for the diagnosis of rhesus incompatibility and clarification of fetal bilirubin metabolism]. PMID- 4217503 TI - [Obtaining type A antienterotoxic serum for diagnosis of staphylococcal food poisoning]. PMID- 4217505 TI - [Long-term effects of nitroglycerin on the heart and peripheral vessels in patients with coronary disease during rest and in frequency-induced angina pectoris]. PMID- 4217506 TI - [Study of some of the antigenic properties of the valvular connective tissue]. PMID- 4217507 TI - [A physiological analysis of intra-species interrelationships between monkeys]. PMID- 4217508 TI - [Motivational components and self stimulation in behavioral reactions induced by electrical stimulation of the cat hypothalamus]. PMID- 4217509 TI - [Formation of interdependent food getting reactions in monkeys]. PMID- 4217510 TI - [Change in the content of A, M and G immunoglobulins in the blood serum of volunteers immunized subcutaneously and enterally against typhoid and paratyphoid]. PMID- 4217511 TI - [Role of the immunological reactivity of the body in the pathogenesis of a resident pathogenic staphylococcal carrier state]. PMID- 4217512 TI - [Problems of immunogenesis in vaccination with live bacterial vaccines. I]. PMID- 4217513 TI - [Immunochemical characteristics of the antigenic makeup of native tetanus toxin]. PMID- 4217514 TI - [Production of monospecific sera against human D and E globulins]. PMID- 4217515 TI - [Sensitivity of different cell cultures to tsutsugamushi rickettsiae]. PMID- 4217516 TI - [The capacity of tsutsugamushi rickettsiae for plaque formation]. PMID- 4217517 TI - [Production of antirickettsial sera in horses. I. Production and approval of immune serum to Prowazek rickettsiae]. PMID- 4217518 TI - [An analysis of egg culture Prowazek rickettsiae, strain E, eith regard to increasing virulence by passage in white mouse lung]. PMID- 4217519 TI - [Structural organization and features of Rickettsia tsutsugamushi interaction with the cell]. PMID- 4217520 TI - [Neuropathologic syndromes in patients with arterial hypotension]. PMID- 4217522 TI - [Usefulness of radiotherapy in the treatment of cutaneous melanoma]. PMID- 4217521 TI - [The diagnostic value of the temporal characteristics of auditory perception in temporal lobe epilepsy]. PMID- 4217524 TI - DNA replication of human acute leukemia cells cultured in vitro. PMID- 4217523 TI - Extrarenal lipid inhibitors of human erythropoietin. PMID- 4217525 TI - Haemolysis and erythrocyte lipids in thalassaemia major. PMID- 4217526 TI - [BCG-non specific immunotherapy of Hodgkin's disease. Preliminary results from a controlled investigation]. PMID- 4217527 TI - Haemoglobin E variants and pregnancy in Malaysian aborigines. PMID- 4217528 TI - Factor X survival and therapeutic factor X levels in the abnormal factor X (factor X FRIULI) COAGULATION DISORDER. PMID- 4217529 TI - [Erythrocytic pyruvate kinase deficiency accompanied by a severe neonatal hemolytic anemia. Family study and biochemical characterization of the enzyme]. PMID- 4217530 TI - Proliferation of erythroblasts in refractory anaemia. A combined autoradiographic and cytophotometric study. PMID- 4217531 TI - In vitro response of bone marrow cells to erythropoietin in aplastic anemia. PMID- 4217533 TI - [Application of light diffusion to the study of platelet volume]. PMID- 4217532 TI - 67Ga scanning in the staging of Hodgkin's disease. PMID- 4217534 TI - Structure and function of haemoglobin Tacoma (beta 30 Arg yields Ser) found in a second family. PMID- 4217535 TI - Congenital dyserythropoietic anaemia type II. Clinical and ultrastructural study. PMID- 4217536 TI - Hereditary disorders of bilirubin metabolism. PMID- 4217537 TI - The activity of intestinal disaccharidases and dipeptidases in rats with chronic renal insufficiency. PMID- 4217538 TI - [Histochemical determination of the isoelectric point in the granulose glands of the skin in several species of amphibia (author's transl)]. PMID- 4217539 TI - [Evidence of myocardial antibodies in paraffin sections (author's transl)]. PMID- 4217540 TI - Histochemical studies on the morphology of the Golgi apparatus and on the distribution of hexokinase, amylophosphorylase, cholinesterases, and monoamine oxidase in the area postrema of the Asiatic chipmunk, Tamias sibiricus asiaticus (T. orientalis). PMID- 4217541 TI - [Electron microscopic-autoradiographic investigation of the distribution of (32P) orthophosphate in the human erythrocyte (author's transl)]. PMID- 4217542 TI - The surface of dissected neurons, neurons in smears, cultivated cells and sections as studied by means of scanning electron microscopy. PMID- 4217543 TI - [Preparative supposition of the combined light and electron microscopic evidence of heavy metals (author's transl)]. PMID- 4217544 TI - [Spleen and immunity: histological and histochemical studies (author's transl)]. PMID- 4217545 TI - Histochemical analysis of thiamine pyrophosphatase activity in the developing molar tooth of the neonatal swiss albino mouse. PMID- 4217546 TI - Quantitative aspects of the colloidal iron reaction. PMID- 4217548 TI - Ancient ophthalmological agents. PMID- 4217547 TI - Modified method of demonstration for zinc in tissues and its mode of existence. PMID- 4217549 TI - Proceedings: Visual information processing, colour vision and spatial localization. PMID- 4217550 TI - The treatment of hypercatabolic acute renal failure by adequate nutrition and haemodialysis. PMID- 4217551 TI - A brain-specific water-soluble antigen in homogenates of cat cerebral cortex. PMID- 4217552 TI - [The confusional states (absence states). Their importance in primary generalized epilepsies, especially in those starting with typical absences (author's transl)]. PMID- 4217553 TI - Neuropathological and biochemical studies in Fabry's disease. PMID- 4217554 TI - The value of histology, culture and guinea pig inoculation examination in osteo articular tuberculosis. PMID- 4217555 TI - Bowel diseases involving local immunoglobulin systems. PMID- 4217556 TI - Influence of synthetic polynucleotides and interferon on in vitro growth of cells derived from a mouse sarcoma. PMID- 4217557 TI - Effects of radiation therapy on blood-borne leucocytes in patients with mammary carcinoma. PMID- 4217558 TI - Absorption of polymyxin E (colistin) by Corynebacterium diphtheriae. PMID- 4217559 TI - Atherosclerosis in pigeons and squirrel monkeys. PMID- 4217560 TI - Social factors and atherosclerosis. PMID- 4217561 TI - Immunologial aspects of atherosclerosis. PMID- 4217562 TI - On species of leucocytozoon. PMID- 4217564 TI - [Morphology and pathology of the retinal glia]. PMID- 4217563 TI - Recent advances in antimalarial chemotherapy and drug resistance. PMID- 4217565 TI - Evidence for defective immunoglobulin metabolism in severe renal insufficiency. PMID- 4217566 TI - Trypanosoma cruzi and virological studies in idiopathic cardiomyopathy in Cali, Colombia. AB - During a 10-year period a series of 114 patients was studied to determine if Trypanosoma cruzi and arboviruses could be the etiologic agents of idiopathic cardiomyopathy (ICM) in Cali, Colombia. In this area, ICM (together with rheumatic and artherosclerotic cardiopathy) represents the second most frequent cause (determined by necropsy) among adult patients with cardiopathies, hypertension being the first. No association was observed between ICM and any of the arboviruses assessed by hemagglutination tests. Only 10 of 114 cases (8.7%) showed positive seroparasitological tests for T. cruzi. Autopsy was performed in 4 of these 10 cases; 1 had Chagas myocarditis and the other 3 were patients with non-inflammatory ICM. In all 9 T. cruzi-negative cases the autopsies showed non inflammatory ICM lesions. In contrast to typical Chagas cases, the most frequent EKG change in ICM is left bundle branch block rather than right. Since the EKG varies within either group, this distinction may not be valid in individual cases. Because of the similarities in clinical characteristics and variations in EKG between Chagas myocarditis and ICM, it is suggested that autopsies should be done in populations in endemic areas of T. cruzi to assess the frequency of ICM and its importance in the differential diagnosis of Chagas myocarditis. PMID- 4217567 TI - The prevalence of trypanosomes and microfilariae in Panamanian monkeys. AB - A total of 3,523 wild caught monkeys from Panama was examined for blood parasites from August 1968 through June 1972. Trypanosomes or microfilariae were observed in the blood of 31.1% of the monkeys. Mixed infections, with microfilariae and trypanosomes, were detected in 6.6% of the animals. Trypanosoma cruzi was found in marmosets. Saguinus geoffroyi (12.2%), in white-faced capuchins, Cebus capucinus (5.0%), in squirrel monkeys, Saimiri sciureus (1.7%) and in black spider monkeys, Ateles fusciceps (1.2%). Trypanosoma rangeli was found in S. geoffroyi (55.8%) and C. capucinus (12.5%). Other trypanosomes found in Panamanian monkeys included T. minasense, and T. mycetae. Saguinus geoffroyi showed the highest infection rate (88.9%) with trypanosomes and/or microfilariae; trypanosomes were seen in 68.1%, and microfilariae in 73.0%, of the animals examined. The marmosets, white-faced capuchins, and squirrel monkeys should be considered as significant hosts of T. cruzi in sylvatic habitats and may serve as reservoir hosts of Chagas' disease in Panama. The microfilariae seen in monkeys from Panama were tentatively identified as larval forms of Dipetalonema gracile in Aotus trivirgatus; D. obtusa in C. capucinus and S. geoffroyi; and D. marmosetae in Alowatta villosa, C. capucinus, A. trivirgatus, S. sciureus, A. fusciceps, and S. geoffroyi. PMID- 4217568 TI - Single and repeated infections of grivet monkeys with Schistosoma mansoni: parasitological and pathological observations over a 31-month period. AB - Groups of 6 to 8 grivet monkeys (Ceropithecus aethiops aethiops), each of which had been exposed to 600 cercariae of Schistosoma mansoni, were killed 3, 6, and 31 months after exposure. Other groups of monkeys were repeatedly challenged with cercariae beginning 4 or 23 months after the initial infection, and were killed 31 months after the first exposure. Peripheral blood leukocytes, eosinophiles, and schistosome eggs passed in the feces were determined during the course of the infection. At autopsy, gross and histopathologic observations were made, worms were recovered by perfusion, and the number of eggs in the tissues was determined by digestion. Monkeys became acutely ill about 8 weeks after the initial exposure, and death was attributed to acute'toxemic' schistosomiasis in 4 of 46 infected animals. The symptoms and signs of the acute phase did not recur with reinfection. Most subsequent natural deaths were caused by Klebsiella infection which occurred in both infected and control monkeys and did not appear to be related to the schistosome infection. Relatively stable infections were found after a single exposure to cercariae, with only a slight decrease in worm numbers and moderate decrease in egg passage after 31 months. With repeated reinfection, only 19% of challenge cercariae developed into adult worms. Oviposition by these worms was delayed and the rate of oviposition was substantially less than in monkeys infected only once. Eggs deposited in the tissues were rapidly destroyed. The calculated rate of oviposition varied from 658 eggs/day per female 3 months after a single infection to 299 eggs/ day per female 31 months after repeated infections. Although very heavy infections were present in repeatedly infected monkeys, only slight hepatic fibrosis was seen and no portal hypertension or portal-systemic collateral circulation developed. Severe intestinal disease was present in only two monkeys. The remaining animals had little diarrhea after the acute phase, and there was only slight loss of plasma protein into the feces 31 months after exposure. PMID- 4217570 TI - Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. I. Clinical course. AB - Fifteen grivet monkeys, Cercopithecus aethiops, were infected with an Ethiopian strain of Borrelia recurrentis, the causative agent of louse-borne relapsing fever. An initial spirochetemia occurred in all. Inactivity, fever, and leukocytosis accompanied the infections. Eight of the monkeys experienced 1 relapse and 1 monkey had 2 relapses. The relapses tended to be less severe than the initial infections. The only deaths, however, occurred in 2 of the 3 monkeys with severe relapses. The clinical course of the experimental infection in grivet monkeys closely resembles that of natural infections in man. PMID- 4217569 TI - Administration and evaluation of rural health services. I. A tetanus control program in Haiti. AB - Tetanus has been a public health problem of major importance in rural Haiti. Energetic preventive measures by a rural Haitian hospital were successful in controlling the problem only after immunization services were made easily available to the entire population served by the hospital. This was accomplished by a program which carried the services to the market places and villages of the region. The program developed several new categories of auxiliary personnel who were recruited locally and trained on the job. These personnel were utilized in a program which incorporated preparatory publicity, timing, handling of large crowds in open surroundings, education, record keeping, follow-up and evulation as well as the technical matters concerning the giving of injections. The program sharply reduced the number of admissions to the hospital for the treatment of tetanus. Evaluated on the basis of hospitalizations avverted the program cost only 1/9 the value of the 50,000 hospital days of care for the tetanus cases it prevented. PMID- 4217571 TI - Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. II. Pathology. AB - Nineteen grivet monkeys, Cercopithecus aethiops, were infected with the spirochete of louse-borne relapsing fever, Borrelia recurrentis, and killed at various intervals following inoculation: 4 during the initial spirochetemia; 4 during remission; 3 during relapse; 2 that were dying following severe relapses; and 6 during convalescence. The histologic changes of histiocytic myocarditis, multiple microabscesses replacing the nodular white pulp of the spleen, and hepatitis with foci of midzonal necrosis were similar to those seen in humans. These changes are rarely seen in other infectious diseases and suggest a specific toxic effect. PMID- 4217572 TI - Experimental louse-borne relapsing fever in the grivet monkey, Cercopithecus aethiops. III. Crisis following therapy. AB - Eight grivet monkeys infected with Borrelia recurrentis received tetracycline (12.5mg/kg body weight) on the 3rd or 4th day of spirochetemia. Leukopenia, fever, hyperpnea, and tachycardia developed within 2 hours as spirochete counts fell to undetectable levels. These events closely simulated the crisis in human louse-borne relapsing fever in both timing and extent. PMID- 4217573 TI - Abnormal patterns of ossification in foot bones of rat fetuses induced by cyclophosphamide. PMID- 4217574 TI - Synthesis of alpha-functional nitrosamines. PMID- 4217575 TI - Dinitrogen(octaethylprophinato)tetrahydrofuranosmium(II): a nitrogen-carrying metalloporphyrin. PMID- 4217576 TI - Purification and immunological quantification of human pancreatic lipase. PMID- 4217577 TI - The effect of high salt concentrations upon cytochrome C, cytochrome B5, and iron EDTA reductase activities of liver microsomal NADPH-cytochrome C reductase. PMID- 4217578 TI - Practolol in angina pectoris: a double-blind ergometric study. PMID- 4217579 TI - [Hybridization of a new species, Drosophila mauritiana, with D. melanogaster and D. simulans]. PMID- 4217580 TI - Penicillin-resistant mechanisms in Pseudomonas aeruginosa: effects of penicillin G and carbenicillin on transpeptidase and C -alanine carboxypeptidase activities. AB - A membrane fraction from Pseudomonas aeruginosa KM 338 was shown to catalyze in vitro peptidoglycan synthesis from uridine 5'-diphosphate-N-acetylmuramyl-l alanyl-d- glutamyl-meso-diaminopimelyl-d-alanyl-d-alanine and uridine 5' diphosphate-N-acetylglucosamine. Synthesized peptidoglycan was partially cross linked by transpeptidation, which was accompanied by the release of d-alanine. This reaction was strongly inhibited by 25 and 50 mug of penicillin G and carbenicillin per ml respectively, whereas the intact cells were relatively resistant to penicillins (minimal inhibitory concentration of penicillin G and carbenicillin, 30 and 0.125 mg/ml, respectively). Soluble d-alanine carboxypeptidase present in P. aeruginosa KM 338 was studied as well, which was found almost completely inhibited by penicillin G and carbenicillin (10 mug/ml). PMID- 4217581 TI - Immunogical study of anti-beta-lactamase antibodies by acidimetric methods. AB - A beta-lactamase was extracted from an Escherichia coli K-12 strain carrying the R-TEM plasmid and has been purified by affinity chromatography. Antisera to this enzyme were prepared in the rabbit, and the enzyme-antibody neutralization reaction has been evaluated with acidimetric methods (pH stat or pH meter). Under defined experimental conditions, it is now possible to clearly illustrate the enzyme-antibody reaction by means of accurate, rapid, and simple-to-perform methods. These methods are in accord with the specificity of the two reactive partners and allow the detection of the enzyme in a crude bacterial extract which would eventually contain more than one beta-lactamase. PMID- 4217582 TI - Antimicrobial actions of hexachlorophene: inhibition of respiration in Bacillus megaterium. AB - Hexachlorophene (HCP) inhibits both endogenous and exogenous respiration (oxygen uptake) in Bacillus megaterium, without sparing by any of several substrates. The inhibition is maximal when the cells are treated with 8 mug of HCP per mg of cells (dry weight), which corresponds to the minimal lethal dose. Levels as low as 2 mug/mg are inhibitory but not lethal. HCP also inhibits the respiration of isolated B. megaterium membranes and can act on several components of the electron transport chain in the membranes and on soluble enzymes. Although both forms of nicotinamide adenine dinucleotide, reduced form dehydrogenase and malic dehydrogenase are inhibited by HCP, they are less susceptible than is oxygen uptake. The site of maximal sensitivity is nearer the terminal electron acceptor, but the exact location depends on the cytochrome composition of the membranes. If cytochromes b(1), a, and a(3) are present, but not o, HCP inhibits electron transport on the substrate side of cytochrome b(1); if cytochromes b(1), a(3), and o are present, but not a, the inhibition occurs on the oxygen side of cytochrome b(1). Exogenous menadione, an analogue of menaquinone, reverses the inhibition in both circumstances. The primary lethal action of HCP thus appears to be respiratory inhibition at a site within the membrane-bound part of the electron transport chain. PMID- 4217583 TI - Induction kinetics of beta-lactamase biosynthesis in Pseudomonas aeruginosa. AB - The induction of beta-lactamase in Pseudomonas aeruginosa 1822s was studied using benzylpenicillin as inducer. The specific rate of beta-lactamase formation was constant throughout an induction experiment. Above a threshold (20 mug/ml), the specific activity increased linearly with the concentration of the inducer. Removal of the inducer resulted in a rapid cessation of beta-lactamase biosynthesis. Inhibition of protein synthesis by starvation for a required amino acid or by the addition of chloramphenicol also led to an instantaneous arrest in enzyme formation. In the absence of inducer, a basal beta-lactamase activity was formed. The basal and the induced enzymes seem to be identical since they had the same substrate profile, electrophoretic mobility, and molecular weight. In all these respects, induction of beta-lactamase in Pseudomonas aeruginosa is analogous to induction of the lac operon in Escherichia coli. However, there was a long, concentration-dependent lag before beta-lactamase was induced. This can be explained by the outer penetration barrier decreasing the rate of inducer uptake. The lag was significantly shorter for lysozyme-ethylenediaminetetraacetic acid-produced spheroplasts than for intact cells. Induction was obtained with all beta-lactam antibiotics tested, but not with other agents affecting the cell envelope. PMID- 4217584 TI - Effects of sublethal concentrations of benzylpenicillin on Pseudomonas aeruginosa. AB - Pseudomonas aeruginosa produces a low basal level of beta-lactamase (0.002 to 0.004 IU/mg of protein when benzylpenicillin is used as substrate). The beta lactamase specific activity can be increased several hundredfold by growing the bacteria in the presence of beta-lactam antibiotics. This induction was studied in Pseudomonas aeruginosa 1822s. The single-cell resistance to benzylpenicillin was 750 mug/ml. In liquid culture all concentrations of benzylpenicillin tested (25 to 2,000 mug/ml) affected the bacteria similarly: beta-lactamase formation was induced, the cells became cholate sensitive, growth rate decreased, filaments were formed, and beta-lactamase was excreted. The effect appeared earlier the higher the concentration of the antibiotic. Most of the effects obtained are concerned with the functioning of the outer membrane. The excretion of beta lactamase seems to be due to an opening of the periplasmic volume rather than to lysis of the cells. Carbenicillin gave the same effects as benzylpenicillin at the same concentrations; the 10-fold lower resistance to carbenicillin than to benzylpenicillin can be explained by the inability of the inducible beta lactamase to hydrolyze carbenicillin. The induced beta-lactamase was first cell bound and to a great extent located in the periplasmic volume, but later it was excreted into the medium. This extracellular activity was responsible for the detoxification of the medium. This is analogous to the behavior of gram-positive bacteria rather than to that of Enterobacteriaceae. PMID- 4217585 TI - Chloroquine-resistant Plasmodium falciparum: effect of substrate on chloroquine and amodiaquin accumulation. AB - Glucose stimulates the high-affinity processes of chloroquine and amodiaquin accumulation in owl monkey erythrocytes infected with a chloroquine-susceptible strain of Plasmodium falciparum. Although these erythrocytes have greater ability to accumulate amodiaquin than chloroquine, glucose has relatively less effect on amodiaquin accumulation than on chloroquine accumulation. In contrast to these findings with chloroquine-susceptible P. falciparum, glucose stimulates amodiaquin but not chloroquine accumulation in erythrocytes infected with chloroquine-resistant P. falciparum. This lack of function of a substrate dependent component of chloroquine accumulation distinguishes chloroquine resistant from chloroquine-susceptible P. falciparum. PMID- 4217586 TI - Properties of an R plasmid in Pseudomonas aeruginosa producing amikacin (BB-K8), butirosin, kanamycin, tobramycin, and sisomicin resistance. AB - Pseudomonas aeruginosa strain GN315, producing kanamycin acetyltransferase, can transmit a plasmid determining resistance to kanamycin, amikacin (BB-K8), butirosin, tobramycin, and sisomicin, but not gentamicin, to other pseudomonas strains. This plasmid, pMG5, belongs to the same incompatibility group as plasmids determining gentamicin resistance in P. aeruginosa via gentamicin acetyltransferase I. Like other members of this group, it also confers resistance to Hg(2+), organomercurials, and certain deoxyribonucleic acid phages. When pMG5 is introduced into a cell carrying a related R factor, some transconjugants can subsequently cotransfer new combinations of resistance determinants as though recombinant plasmids had been formed. PMID- 4217587 TI - Penicillin: reversible inhibition of forespore septum development in Bacillus megaterium cells. AB - Benzylpenicillin inhibits the development of the forespore septum in sporulating Bacillus megaterium cells. The inhibitory effect is a function of the duration of exposure to the antibiotic and is completely reversible by penicillinase. Under the incubation conditions employed, less than 20% of the covalently bound antibiotic is released from the cells. The penicillin which remains bound to the cells after treatment with penicillinase may be necessary but is not sufficient for the effect; unbound antibiotic in the sporulation medium is also required. PMID- 4217588 TI - Ecological application of antibiotics as respiratory inhibitors of bacterial populations. AB - Two terregenous and four marine bacterial isolates were treated with six antibiotics and antibiotic combinations. Comparisons made between responses of cells in early and late logarithmic and stationary growth phases indicated variable sensitivity to the agents. Bacteria in stationary and late log-phase cultures exhibited the greatest resistance, whereas the early log-phase cells exhibited greatest antibiotic susceptibility. We conclude that the tested antibiotics cannot be used for ecological purposes to delineate bacterial respiration in mixed microbial communities. PMID- 4217589 TI - Antagonism of lactic streptococci toward Staphylococcus aureus in associative milk cutures. AB - The inhibition of growth of Staphylococcus aureus by lactic streptococci in associative cultures in milk was not due to hydrogen peroxide produced by the streptococci. Dialyzed whey from the milk culture of lactic streptococci was more inhibitory than dialyzed whey from milk acidified with lactic acid, indicating that material other than lactate was also involved. Analyses of cation and anion exchange fractions from the dialyzed whey showed that only the neutral fraction was inhibitory. PMID- 4217590 TI - Detecting the enterotoxigenicity of Staphylococcus aureus strains. AB - An optimal sensitivity plate method for examining large number of staphylococcal strains for production of the known enterotoxins (A-E) is presented. Small volumes of relatively concentrated enterotoxin are produced by the semi-solid agar, cellophane-over-agar, or sac culture techniques. Detection of the enterotoxin in the supernatant fluid is accomplished with the optimal sensitivity plate method. In this method small plastic petri dishes (50 mm) were used for a modified Ouchterlony of high sensitivity. PMID- 4217591 TI - Agricultural plants and soil as a reservoir for Pseudomonas aeruginosa. AB - Pseudomonas aeruginosa was detected in 24% of the soil samples but in only 0.13% of the vegetable samples from various agricultural areas of California. The distribution of pyocin types of soil and vegetable isolates was similar to that of clinical strains, and three of the soil isolates were resistant to carbenicillin. Pseudomonas aeruginosa multiplied in lettuce and bean under conditions of high temperature and high relative humidity (27 C and 80-95% relative humidity) but declined when the temperature and humidity were lowered (16 C, 55-75% relative humidity). The results suggest that soil is a reservior for P. aeruginosa and that the bacterium has the capacity to colonize plants during favorable conditions of temperature and moisture. PMID- 4217592 TI - IgE levels in sera of patients with pemphigus or bullous pemphigoid. PMID- 4217593 TI - Circulatory responses to bacterial cardio-stimulating substances in hemorrhagic dogs. PMID- 4217594 TI - [The formation of traces of carbon monoxide by Saccharomyces cerevisiae and other microorganisms (author's transl)]. PMID- 4217595 TI - Studies on the cell cycle of Myxobacter AL-1. I. Size fractionation of exponentially growing cells by zonal centrifugation. PMID- 4217596 TI - Freeze-etching of the outer membranes of Pseudomonas and Acinetobacter. PMID- 4217597 TI - [Bacilliferous tuberculosis and sensitivity of Koch bacilli to tuberculostatic drugs (current situation in a French hospital service)]. PMID- 4217598 TI - [Incidence of primary resistance to antitubercular agents in the Toulouse area]. PMID- 4217599 TI - [Relations between resistance and virulence of mycobacteria]. PMID- 4217600 TI - [Contagion of drug-resistant Mycobacterium tuberculosis: considerations on the time course of so-called primary resistance]. PMID- 4217601 TI - [Primary resistance of Mycobacterium tuberculosis. Bacteriological and epidemiological aspects]. PMID- 4217602 TI - [The phenomenon of primary mycobacterial resistance in the records of the Clinica Tisiologica di Parma]. PMID- 4217603 TI - [The incidence of primary mycobacterial resistance in the records of the Clinica Tisiologica di Catania]. PMID- 4217604 TI - [Contagion in tuberculosis at the present time: conclusive summary of the Convention]. PMID- 4217605 TI - [Host cell-dependent density differencies of the intra- and extraviral vaccinia virus hemagglutinins]. PMID- 4217606 TI - Positive reaction between australia antigen and anti-human liver antibody. PMID- 4217607 TI - Herpesvirus--a possible cause of low fertility in male turkeys. PMID- 4217608 TI - Serum concentration of pregnancy-specific beta-1-glycoprotein (sp-1) in normal and pathologic pregnancies. PMID- 4217609 TI - [Immunochemical investigations on the protein of the "pregnancy zone". VIII. Investigations of enzyme and isoenzyme activities of the pregnancy zone protein and its immunochemical detection in urine during normal and pathologic course of pregnancy (author's transl)]. PMID- 4217610 TI - [Effect of neutron irradiation on sedimentation of cellular DNA (author's transl)]. PMID- 4217611 TI - Antibacterial action of complexing compounds. II. Influence of disodium ethylendiaminetetraacetate (NA2EDTA) on experimental infection with Pseudomonas aeruginosa in mice. PMID- 4217613 TI - Annual directory. Membership roster. Arkansas State Dental Association. PMID- 4217614 TI - Clinical use of some dental materials composite restorative materials. PMID- 4217612 TI - Effects of medium chain triglycerides on plasma free fatty acids in normal subjects. PMID- 4217615 TI - Editorial: Two threats to survival. PMID- 4217616 TI - [Infectious and immunologic aspects of burn disease]. PMID- 4217617 TI - [Effect of the pathogenic agent on the localization and structure of metastatic foci in sepsis]. PMID- 4217618 TI - [Amyloidosis in monkeys of the Sukhumi arboretum]. PMID- 4217619 TI - Collagen turnover in the gingiva and other mature connective tissues of the marmoset Saguinus oedipus. PMID- 4217620 TI - Growth of Streptococcus mutans in a chemostat. PMID- 4217621 TI - Human parotid IgA and periodontal disease. PMID- 4217622 TI - Life times: Alice Muller. PMID- 4217623 TI - The use of esophageal motility studies in the diagnosis of dysphagia. PMID- 4217624 TI - Some difficulties in the treatment of dysphagia in adults. PMID- 4217625 TI - Cidex-sterilising solution chemical. PMID- 4217627 TI - [Anatomy of the peripheral visual pathway]. PMID- 4217626 TI - The hippocampus and contextual retrieval of information from memory: a theory. PMID- 4217628 TI - Mitochondrial and cytoplasmic ribosomes. Distinguishing characteristics and a requirement for the homologous ribosomal salt-extractable fraction for protein synthesis. AB - 1. Mitochondrial and cytoplasmic ribosomes of Euglena gracilis differ in their total RNA and protein content. 2. Mitochondrial ribosomes dissociate to subunits at higher Mg(2+) concentrations than do cytoplasmic ribosomes. 3. A separable 5S RNA is obtained from cytoplasmic and chloroplast ribosomes, but not from mitochondrial ribosomes. 4. For protein-synthesizing activity with a natural mRNA, mitochondrial ribosomes use tRNA from any cell compartment and are partly active with supernatant enzymes from cytoplasm. Cytoplasmic ribosomes are partly active with enzymes and tRNA from mitochondria or chloroplasts. 5. Both mitochondrial and cytoplasmic ribosomes show high specificity for the homologous salt-extractable ribosomal fraction for protein-synthesizing activity. PMID- 4217629 TI - Pseudoperoxidase activity of mushroom tyrosinase. PMID- 4217630 TI - [Absorption, distribution and excretion of penicillin V in rats. 2. Compartment studies]. PMID- 4217631 TI - The effects of anti-arthritic gold compounds on mycoplasma and leishmania. PMID- 4217632 TI - Anthelminthic efficacy of diospyrol and its derivatives. PMID- 4217633 TI - [Tissue culture of hepatic tissue, obtained by needle biopsy as a method for the study of Australia antigen]. PMID- 4217634 TI - Central haemodynamics during spontaneous angina pectoris. PMID- 4217636 TI - Parenteral nutrition. PMID- 4217637 TI - The hyperviscosity syndrome. PMID- 4217635 TI - Studies on the pathogenesis of experimental chronic active hepatitis in rabbits. II. Demonstration of immunoglobulin on isolated hepatocytes. PMID- 4217638 TI - Effect of ferrous ions on microsomal phospholipid peroxidation and related light emission. PMID- 4217639 TI - Partial specific volume and molecular weight determinations from sedimentation equilibrium experiments in H2O and H2-18O. Study of an immunomacroglobulin type lambda, (IgM) Lambda. PMID- 4217640 TI - Supplementary feeding during the preweaning period. Effect on carcass composition and adipose tissue cellularity of the rat. PMID- 4217641 TI - Evolution of titre of serum IgG in newborn. PMID- 4217642 TI - Proceedings: Effect of cromoglycate and eicosatetraynoic acid on the release of prostaglandins and SRS-a from immunologically challenged guinea pig lungs. PMID- 4217643 TI - Effects of dipyridamole on neurogenic and non-neurogenic dilator responses of arterial smooth muscle. AB - 1 In the isolated, perfused parametrial artery of the guinea-pig dipyridamole (10 100 ng/ml) potentiated dilator responses to adenosine 5'-triphosphate (ATP), glyceryl trinitrate and non-cholinergic, non-adrenergic inhibitory nerve stimulation to similar extents. In contrast dilator responses to acetylcholine were generally unaffected or reduced.2 These results support previous electro physiological evidence that in this preparation cholinergic vasodilatation is mediated by a cellular mechanism different from that involved in the response to non-cholinergic dilator nervous activation.3 The results also suggest that potentiation of a neurally-mediated inhibitory response of smooth muscle by dipyridamole does not necessarily implicate ATP as the transmitter involved in this response. PMID- 4217645 TI - Serological investigations on endotoxins isolated from Sphaerophorus funduliformis (syn. Fusobacterium necrophorum) strains. PMID- 4217644 TI - Experience with treatment of primary malignant disease of the prostate by localised external supervoltage irradiation using cobalt-60 or high energy electrons. PMID- 4217646 TI - Comparative immunochemical studies on the endotoxins of two Fusobacterium necrophorum strains. PMID- 4217647 TI - [Peroperative radiomanometry]. PMID- 4217648 TI - [Difficulties of cortisone severage in asthma]. PMID- 4217649 TI - Chemistry of the renal reabsorption of bicarbonate. PMID- 4217651 TI - [Parenteral nutrition, theory and practice. Water, ions, sugars]. PMID- 4217650 TI - Turnover and metabolism of polychlorinated biphenyls in relation to their chemical structure and the movement of lipids in the pigeon. PMID- 4217652 TI - [Comparison between the effects of carbenicillin and new penicillin BRL-2288 on a model of B. pyocyaneus pyelonephritis in rats (author's transl)]. PMID- 4217653 TI - [Cannulation of central veins via internal jugular vein (author's transl)]. PMID- 4217654 TI - A differential effect of IgM and IgG antibodies on the blastogenic response of lymphocytes to rubella virus. PMID- 4217655 TI - Studies on antigenic competition. Efforts to identify the cellular basis of competition using a cell transfer system. PMID- 4217656 TI - Surface immunoglobulin of mouse thymus cells and its in vitro biosynthesis. PMID- 4217658 TI - [Determination of iodinated compounds in the blood. III. Modified semiautomated determination of thyroxine in the blood serum]. PMID- 4217657 TI - Effect of thymus cell injections on germinal center formation in lymphoid tissues of nude (thymusless) mice. PMID- 4217660 TI - Studies on kallikreins. III. Intra-intestinal administration of hog pancreatic kallikrein and its appearance in the perfusate from the mesenteric vein. PMID- 4217659 TI - [Levels of immunoglobulins G,A,M,D and E in the current population of children]. PMID- 4217662 TI - The properties of alpha-galactosidase remaining in kidney and liver of patients with Fabry's disease. PMID- 4217661 TI - The chemistry and control of hereditary lipid diseases. PMID- 4217663 TI - [Peroxidase activity of sporadic human goiters and induced rat goiters]. PMID- 4217664 TI - [Influence of lighting period and feeding time in the control of circadian activity of cholesterol 7-alpha-hydroxylase in the rat]. PMID- 4217665 TI - [Origin of transbranchial electric potential difference in the goldfish Carassius auratus. Importance of Ca++ ion]. PMID- 4217666 TI - [Influence of intensive regeneration on the calcium level in the crab Pachygrapsus marmoratus (Fabricius, 1787) deprived of its Y organs]. PMID- 4217667 TI - [Influence of a prostaglandin analog (ICI 80996) and a progestagenic hormone on corpus luteum life span and on the appearance of estrus in bovines]. PMID- 4217668 TI - [Several cytological aspects of testis regression in the quail chick withdrawn from photostimulation]. PMID- 4217669 TI - [Contribution of the somitic mesoderm to limb genesis in bird embryos]. PMID- 4217670 TI - [Demonstration of tolerance to the Doppler effect of the sonar emission of Delphinus delphis (Cetacean Odontocete)]. PMID- 4217672 TI - [Nucleolar stimulation and early effects of estradiol in the rat uterus]. PMID- 4217671 TI - [Variation of the low frequency impedance of the human body during hemodialyses and therapeutic diuresis]. PMID- 4217673 TI - [Isolation of bovine erythrocyte carbonic anhydrase by affinity chromatography]. PMID- 4217674 TI - [Lymphocyte stimulation in chronic lymphatic leukemia]. PMID- 4217675 TI - [Action of synthetic TRH on the rat thyroid gland during pregnancy and fetal newborn stages]. PMID- 4217676 TI - Diseases of the hypothalamus and pituitary gland. PMID- 4217677 TI - Evidence for the activation of complement via the alternate pathway in skin diseases. II. Dermatitis herpetiformis. PMID- 4217678 TI - A human monoclonal IgM with binding activity for C-reactive protein (CRP). PMID- 4217679 TI - The interaction of lupus-inducing drugs with deoxyribonucleic acid. PMID- 4217682 TI - Larval-specific serum protein in the order Dictyoptera I. Immunologic characterization in larval Blattella germanica and cross-reaction throughout the order. PMID- 4217681 TI - Chemical composition of the cuticle, and the inner and outer shell membranes from eggs of Gallus gallus. PMID- 4217680 TI - A review: The obese strain (OS) of chickens: an animal model with spontaneous autoimmune thyroiditis. PMID- 4217683 TI - Disorders of the autonomic nervous system. Chapter 14. The alimentary tract. PMID- 4217684 TI - Predicting the stabilities of freeze-dried suspensions of Lactobacillus acidophilus by the accelerated storage test. PMID- 4217685 TI - Cryosurgery of the rabbit prostate. Comparison of the immune response of immature and mature bucks. PMID- 4217686 TI - The effect of abrupt changes in sodium chloride concentration upon the viability of gram-negative bacteria at 2 and 40 degrees C. PMID- 4217687 TI - Child abuse: one tree in the forest. PMID- 4217688 TI - [Finnish population as an object of epidemiological studies]. PMID- 4217689 TI - Epilepsy due to cerebral cysticercosis. PMID- 4217690 TI - Childhood epileptic encephalopathy with slow spike-wave. A statistical study of 80 cases. PMID- 4217691 TI - Pharmacoligic prophylaxis of posttraumatic epilepsy. A review. PMID- 4217692 TI - Epilepsy with multiple sclerosis. PMID- 4217693 TI - Proceedings: Responsiveness at the onset of spike-wave bursts. PMID- 4217695 TI - Proceedings: Focal spikes in childhood and the concept of "functional" spike activity. PMID- 4217694 TI - Proceedings: A multifactorial analysis of focal and generalized cortico-reticular (centrencephalic) epilepsy. PMID- 4217696 TI - Proceedings: Long-term follow-up of children with grand mal seizures. PMID- 4217697 TI - Interaction between beta-lactam antibiotics and exocellular DD-carboxypeptidase transpeptidase of Streptomyces R61. PMID- 4217698 TI - [Proceedings: T3 suppression and TRH tests in hyperthyroidism following treatment with 131 I]. PMID- 4217699 TI - [Proceedings: TRH test in hyperfunctioning nodular goiter]. PMID- 4217700 TI - [Proceedings: TRH tolerance test in normal pregnancy]. PMID- 4217701 TI - [Proceedings: Serum triiodothyronine concentration and TRH test in patient with molar pregnancy]. PMID- 4217702 TI - [Proceedings: Clinical significance of oral TRH test in various endocrine diseases]. PMID- 4217703 TI - [Proceedings: Relationship between thyroid functions and TRH test in Basedow's disease]. PMID- 4217704 TI - [Proceedings: Functions of the diencephalon-pituitary system in chronic renal insufficiency: with special reference to TRH test]. PMID- 4217705 TI - [Proceedings: TRH test in chronic renal insufficiency]. PMID- 4217706 TI - [Proceedings: TSH response in TRH loading test in patients with obesity. 2. A comparison with thin patients]. PMID- 4217707 TI - [Proceedings: Effect of T4 binding protein on thyroid hormone secretion]. PMID- 4217708 TI - [Proceedings: Thyroxine binding globulin (TBG) and estradiol in the maternal system and fetus: the effect of estradiol on TBG]. PMID- 4217709 TI - [Proceedings: Endocrinological study of primates. 3. Effect of ovulation induction agents on female rhesus monkeys during the sterile period in summer]. PMID- 4217710 TI - [Proceedings: Effect of synthetic TRH administration on luteinizing function]. PMID- 4217711 TI - [Proceedings: Experimental evaluation of TRH radioimmunoassay]. PMID- 4217713 TI - [Proceedings: TRH radioimmunoassay II: determination of urinary TRH]. PMID- 4217712 TI - [Proceedings: Radioimmunoassay of TRH]. PMID- 4217714 TI - [Proceedings: TRH radioimmunoassay III: determination of TRH in the blood]. PMID- 4217715 TI - [Proceedings: Simple determination of free thyroxine index and TBG index and its clinical evaluation]. PMID- 4217716 TI - [Proceedings: Reserve TSH releasing potential of the pituitary gland in diabetes: correlation between the diabetic state and the result TRH test]. PMID- 4217717 TI - [Proceedings: Phylogenic evaluation of TRH non-activation]. PMID- 4217718 TI - [Proceedings: Prolactin response in various stimulation tests in pituitary dwarfism]. PMID- 4217719 TI - [Proceedings: Effect of TRH on pituitary hormone, especially growth hormone secretion, in depression]. PMID- 4217720 TI - [Proceedings: Blood prolactin and TSH responses to TRH in various diseases]. PMID- 4217721 TI - [Proceedings: Urinary 6 beta-hydroxycortisol (6 beta-OH-F) level at the time of phenobarbital administration in patients with PCB poisoning]. PMID- 4217722 TI - [Proceedings: LH-RH and TRH reactions in dietary amehorrhea and anorexia nervosa]. PMID- 4217723 TI - [Proceedings: Case of cretinism in an infant with an ectopic thyroid (in the sublingual region) and an abnormally low TBG level]. PMID- 4217724 TI - [Proceedings: Relationship between TRH test and T3 suppression test during the treatment of hyperthyroidism]. PMID- 4217725 TI - [Proceedings: Therapy and TRH-TSH response in hyperthyroidism]. PMID- 4217726 TI - [Proceedings: Clinical study of the treatment with TRH. 3. Effect of repeated TRH administration]. PMID- 4217727 TI - [Proceedings: Effect of synthetic TRH on pregnant rats, the conceptus and newborn animals]. PMID- 4217728 TI - [Proceedings: Decerebrate experiment on TRH response of the rat embryo in utero]. PMID- 4217729 TI - [Proceedings: Hypothalamic TRH secretion and dopaminergic mechanism]. PMID- 4217730 TI - [Proceedings: Various factors influencing pituitary TSH release in rats. 2. Effects of synthetic TRH and its analogues]. PMID- 4217731 TI - [Proceedings: TSH secretory dynamics in various thyroid diseases: with special reference to TRH tolerance test during the period of normal thyroid function]. PMID- 4217732 TI - [Proceedings: TRH test in chronic thyroiditis: with special reference to the relationship with histological observations]. PMID- 4217733 TI - [Proceedings: T3 suppression test and TRH test in preoperative and postoperative periods in hyperthyroidism]. PMID- 4217734 TI - The effect of beta-ecdysone on protein synthesis in imaginal discs of Drosophila melanogaster cultured in vitro. PMID- 4217735 TI - The effect of beta-ecdysone on protein synthesis in imaginal discs of Drosophila melanogaster cultured in vitro. PMID- 4217737 TI - [New instrumental means for the medical use of very high energy particles]. PMID- 4217736 TI - The treatment of lactic acidosis in the diabetic patient by peritoneal dialysis using sodium acetate. A report of two cases. PMID- 4217739 TI - Nasogastric tube feeding. PMID- 4217738 TI - Leucine tolerance in protein-calorie malnutrition. PMID- 4217740 TI - Lactose absorption in protein-calorie malnutrition. PMID- 4217741 TI - Classification and epidemiology of protein-calorie malnutrition. PMID- 4217742 TI - The glycogenolytic activity in protein-calorie malnutrition. PMID- 4217743 TI - Dietary faults in health and disease leading to protein-calorie malnutrition. PMID- 4217744 TI - Parenteral feeding. PMID- 4217745 TI - Treatment of protein--calorie malnutrition using a protein rich food (AN-68) based on "Bellila dish". PMID- 4217746 TI - Histologic identification and immunochemical studies of prolactin and growth hormone in the primate pituitary gland. PMID- 4217747 TI - Positive selection for mating with functional heterokaryons in Tetrahymena pyriformis. AB - Allelic assortment of Tetrahymena pyriformis makes possible the isolation of cells which contain both a heterozygous germ line nucleus and a somatic nucleus which expresses phenotypes of only one member of allelic pairs. Cycloheximide sensitive segregants have been isolated from the vegetative progeny of cells heterozygous for a dominant mutation conferring resistance to cycloheximide; such segregants are called functional heterokaryons. Since progeny from crosses of these cells are cycloheximide-resistant, addition of the drug provides positive selection for successful exconjugants. The timing for expression of the new phenotype during conjugation is presented and used to identify what appear to be immature progeny of round one mating in genomic exclusion. Usefulness of functional heterokaryons in a number of genetic and developmental studies is discussed. PMID- 4217748 TI - Genetic limits of the xanthine dehydrogenase structural element within the rosy locus in Drosophila melanogaster. AB - Experiments are described that provide an opportunity to estimate the genetic limits of the structural (amino acid coding) portion of the rosy locus (3:52.0) in Drosophila melanogaster, which controls the enzyme, xanthine dehydrogenase (XDH). This is accomplished by mapping experiments which localize sites responsible for electrophoretic variation in the enzyme on the known genetic map of null-XDH rosy mutants. Electrophoretic sites are distributed along a large portion of the null mutant map. A cis-trans test involving electrophoretic variants in the left- and right-hand portions of the map leads to the conclusion that the entire region between these variants is also structural. Hence most, if not all, of the null mutant map of the rosy locus contains structural information for the amino acid sequence of the XDH polypeptide. Consideration is given to the significance of the present results for the general problem of gene organization in higher eukaryotes. PMID- 4217749 TI - Ribosomal gene magnification in Drosophila: a chromosomal change. AB - The sex-linked mutant "bobbed" can undergo a rapid phenotypic reversion during a prescribed series of outcrosses. The experiments reported here distinguish between two general genetic models. The first is that the phenotypic change results from the changing genetic background brought about by the outcrosses. The second is that the phenotypic change results from an alteration of the X chromosome in the germ line. The data support the second model. It is shown that both the bobbed and reverted phenotypes segregate from the same female. In addition, the reverted phenotype maps in or near the proximal heterochromatin of the X chromosome, which is the standard map position of both bobbed and the nucleolus organizer. PMID- 4217750 TI - Linkage disequilibrium in natural populations of Drosophila melanogaster. AB - Two large, stable populations (Texas and Japan) of Drosophila melanogaster were surveyed at 21 allozyme loci on the second and third chromosomes and for chromosomal gene arrangements on those two chromosomes. Over 220 independent gametes were sampled from each population. The types and frequencies of the surveyed genetic variation are similar to those observed previously and suggest only slight differentiation among geographically distant populations. Linkage disequilibrium among linked allozymes loci is only slightly, if at all, detectable with these sample sizes. Linkage disequilibrium between linked inversions and allozymes loci is common especially when located in the same arm. These disequilibria appear to be in the same direction for most comparisons in the two population samples. This result is interpreted as evidence of similar selective environments (ecological and genetic) in the two populations. It is also noted that the direction of these linkage disequilibria appears to be oriented with respect to the gene frequencies at the component loci. PMID- 4217751 TI - The direction of linkage disequilibrium. AB - The previous paper (Langley, Tobari and Kojima 1974) reports that the directional linkage disequilibria, D(omega) = P(AB)P(ab)-P(Ab)P(aB), tend to be negative for data between allozymes and linked to inversions. A and B stand for the two alleles with the greatest frequency in the population. In this paper we show that linkage disequilibrium in this direction is produced at equilibrium when double homozygotes have fitnesses that are a constant fraction of the product of the two component single homozygote fitnesses, a pattern that is frequently observed in experimental data. PMID- 4217752 TI - Population structure in artificial selection: studies with Drosophila melanogaster. PMID- 4217753 TI - Genetic analysis of larval feeding behaviour in Drosophila melanogaster. PMID- 4217754 TI - Physiological genetics of melantoic tumours in Drosophila melanogaster. VIII. The role of choline in the expression of the tumor gene tu bw and of its suppressor, su-tu. PMID- 4217755 TI - The mode of attachment and relation to the host in Apiosoma piscicola Blanchard and Epistylis lwoffi Faure-Fremiet, ectocommensals of freshwater fish. PMID- 4217756 TI - Thyrotropin responses to TRH in depressive illness: relation to clinical subtypes and prolonged duration of depressive episode. PMID- 4217757 TI - Investigations on the antilipolytic activity of sulfonylureas in man with indications on limit dosages concerning their insulin-secreting properties. PMID- 4217758 TI - Impaired prolactin response to synthetic thyrotropin-releasing hormone after a 36 hour fast. PMID- 4217759 TI - The effect of thyrotrophin-releasing hormone on serum TSH, T-4, and T-3 levels in endemic and sporadic nontoxic goitre. PMID- 4217760 TI - Effect of the antiestrogen nafoxidine on the occurrence of estrogen-dependent renal tumors in hamster. PMID- 4217761 TI - Thyroid hormone levels in adult protein calorie malnutrition (PCM). PMID- 4217762 TI - Use of papain in the preparation of adult mammalian skeletal muscle for tissue culture. PMID- 4217763 TI - Origin of endogenous and exogenous agents in cell cultures. PMID- 4217764 TI - A new method for dispersing strongly adhesive cells in tissue culture. PMID- 4217767 TI - The cardiac autoimmune system. VII. Heart specific auto-antibodies produced in rabbits immunized with human heart. PMID- 4217765 TI - Preparation of a relatively acid-stable antigen (CEA) by disruption of its specific precipitate with antibody. PMID- 4217766 TI - Production of antibodies to carcinoembryonic antigen in tolerant rabbits. PMID- 4217768 TI - A method for assessing the in vitro chemotactic response of neutrophils utilizing 51cr-labeled human leukocytes. PMID- 4217769 TI - Method of quick detection of antigen-antibody precipitin reaction. PMID- 4217770 TI - Anti-SRBC plaque-forming cells in liver, spleen and hepatocyte cell suspensions of rabbits and mice. PMID- 4217771 TI - The influence of the shape of phagocytes on their adhesiveness. PMID- 4217772 TI - Inhibition of rosette formation by spleen cells of immunized mice by antibodies to aggregated mouse immunoglobulins. PMID- 4217773 TI - Characterization of subunits from a reconstituted monoclonal IgM that binds IgG. PMID- 4217774 TI - Hydrosoluble immunopotentiating substances extraced from Corynebacterium parvum. PMID- 4217775 TI - Leucocyte migration inhibition as a model for the demonstration of sensitized cells in East Coast fever. PMID- 4217776 TI - Non-covalent association of IgM subunits produced by reduction and alkylation. PMID- 4217777 TI - A critical study of the IgG subclasses of Rh anti-D antibodies formed in pregnancy and in immunized volunteers. PMID- 4217778 TI - The effect of homologous and heterologous carriers on the immunogenicity of the galactocerebroside hapten. PMID- 4217779 TI - Palyam group: a new serogroup of arboviruses: physicochemical and biological properties of Palyam and Kasba viruses. PMID- 4217780 TI - A psychoanalytic psychotherapy of a patient with cerebral palsy: the relation of aggression to self and body representations. PMID- 4217781 TI - Cellular regulation in sexual development. PMID- 4217782 TI - Evaluation of media used for cultures of Neisseria gonorrhoeae and comparison of commercial and laboratory prepared supplements. PMID- 4217784 TI - Criteria for cure of gonorrhea. How reliable are they? PMID- 4217783 TI - Microepidemic of virulent gonococcal infection. PMID- 4217785 TI - Evaluation of self-obtained cultures using a vaginal tampon as a method of screening for asymptomatic gonorrhea on a college campus. PMID- 4217786 TI - Steffimycin B, a new member of the steffimycin family: isolation and characterization. PMID- 4217787 TI - Microbial production of vitamin B12 antimetabolites. I. N5-hydroxy-L-arginine from Bacillus cereus 439. PMID- 4217788 TI - Aminoglycoside antibiotics. VII. Synthesis and activity of 4'-deoxykanamycin A. PMID- 4217789 TI - Aminoglycoside antibiotics. IX. 1-N-acyl derivatives of kanamycin A (amikacin analogs). PMID- 4217790 TI - The mode of action of polyketoacidomycin on Bacillus subtilis. PMID- 4217792 TI - The synthesis of 1-N-[(S)-4-amino-2-hydroxybutyryl]gentamicin C1 and 1-N-[ (S) -3 amino-2-hydroxypropionyl]gentamicin C1. PMID- 4217791 TI - On the mode of action of ASK-753, a new iron-containing antibiotic. PMID- 4217793 TI - Studies on the biosynthesis and morphogenesis of R-type pyocins of Pseudomonas aeruginosa. IV. Quantitative estimation of the rates of synthesis of pyocin R subunit proteins. PMID- 4217794 TI - Phosphoenolpyruvate carboxylating enzyme in dark-grown and in green Euglena cells. PMID- 4217795 TI - Lack of exchange of ribosomal structural proteins with cell-sap proteins of rat liver in vitro. PMID- 4217796 TI - Inhibition by analogues of the hydrolysis of phenyl alpha-maltoside catalyzed by saccharifying alpha-amylase from Bacillus subtilis. PMID- 4217797 TI - Ectopic ossification following total hip replacement. Incidence and a method of classification. PMID- 4217798 TI - Rickets, osteomalacia, and renal osteodystrophy. Part II. PMID- 4217799 TI - The Rhesus factor in occlusive and ectatic arterial disease. PMID- 4217800 TI - Glutaraldehyde fixation of isolated eucaryotic nuclei. Evidence for histone histone proximity. AB - Isolated chicken erythrocyte nuclei have been incubated with dilute concentrations of the bifunctional cross-linking agent glutaraldehyde (0-20 mM) in order to stabilize histone-histone interactions within the native nucleus. The kinetics of the disappearance of acid-soluble histones, free amino groups, and of individual histones have been observed to be pseudo first-order. Apparent first order rate constants for the disappearance of individual histones correlate with the lysine mole percent of that fraction and follow the ranking, k(app): F1 > F2C > F2B >/= F2A2, F2A1, F3. Histone polymers were observed to form very rapidly during the fixation reaction. Partial fractionation and amino acid analyses of these polymers support the view that they are composed principally of cross linked (F2C)(n) molecules (where n = 2 to approximately 8). The rate of glutaraldehyde reaction with free amino groups in histones is drastically reduced in solvents that promote chromatin decondensation (i.e., low ionic strengths in the absence of divalent cations) whereas the formation of cross-linked F2C polymers is less severely reduced. It is proposed that some F2C histones exist in close proximity within the isolated erythrocyte nucleus. PMID- 4217802 TI - Development of high resolution pyrolysis-gas chromatography for the identification of microorganisms. PMID- 4217801 TI - The synthesis and turnover of rat liver of rat liver peroxisomes. IV. Biochemical pathway of catalase synthesis. AB - Early events in the biosynthesis of liver catalase were studied on female rats receiving [(3)H]leucine or [(3)H]delta-aminolevulinic acid or a mixture of [(3)H]leucine with [(14)C]delta-aminolevulinic acid by intraportal injection. Catalase antigen was selectively separated from homogenates by immunoprecipitation, both without and after partial purification of the enzyme. Label from both precursors appeared first in immunoprecipitable material which was lost upon purification of catalase; the label subsequently became associated with material indistinguishable from catalase. Kinetic analysis of the results indicates that the nonpurifiable material identified by early labeling consists of two distinct biosynthetic intermediates, the first lacking heme and representing about 1.6% of the total catalase content or 13 microg/g liver, the second containing heme and representing about 0.5% of the total catalase content or 4 microg/g liver. The first intermediate migrates at the same rate as catalase upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and therefore has a monomeric molecular weight of about 60,000. PMID- 4217803 TI - The effect of age upon the coagulation system. AB - Factors V, VII, VIII, X, XI, and XII of the coagulation system, platelet count, and antithrombin III levels were assayed in 20 healthy volunteers aged 20-40 years and 61 elderly subjects aged 66-96 years whose skinfold thickness was also measured. Factors XI, XII, and antithrombin III levels tended to increase in women and decrease in men while factors X, VII, and V tended to increase in both males and females with advancing years. No age or sex differences were found in platelet counts or factor VIII levels. Factor VIII levels were inversely correlated with obesity in elderly males (r = -0.56, p < 0.005). PMID- 4217804 TI - The pre-albumin fraction: a useful parameter in the interpretation of routine protein electrophoresis. AB - A technique of protein electrophoresis suitable for routine use which ensures good separation of the prealbumin fraction is described. The clinical value of visually estimating this protein fraction from the electrophoretic strip is shown with reference to 134 cases. Low levels of prealbumin were found to be associated with liver disorders, malignancy, collagen diseases, congestive cardiac failure, and burns. Finally, pitfalls in electrophoretic technique which may cause failure to visualize the prealbumin fraction are discussed. PMID- 4217805 TI - Bacterial flora of the appendix fossa in appendicitis and postoperative wound infection. AB - Bacteria were isolated from 153 (47.5%) swabs of the appendix fossa in 322 patients undergoing appendicectomy. The commonest organism was Bacteroides species found in 78% of specimens. Other Gram-negative bacilli such as Klebsiella, or Enterobacter, and Esch. coli were present in 29 and 27% respectively. Gram-positive cocci were less frequently isolated.A positive culture was obtained more commonly in perforated appendicitis (79%) than where chronic fibrosis, lymphoid hyperplasia, or acute appendicitis was present or when the appendix was normal. Bacteroides was isolated twice as often in perforated appendicitis. The incidence of wound infection was 19% and varied according to the state of the appendix, being 63% in perforated appendicitis and 9.5% where lymphoid hyperplasia was present. Bacteroides was isolated from over 90% of the wound infections. In the patients with perforated appendicitis where effective chemotherapy was given the incidence of wound infection was 15% whereas in untreated or inappropriately treated patients it was over 50%. The isolation of bacteroides requires special precautions to be taken both in the collection of the specimen and laboratory culture. It is important that the chemotherapy of postappendicectomy infections include an antibiotic active against bacteroides. PMID- 4217807 TI - Hepatitis-associated antigen in various population groups in Upper Egypt. PMID- 4217806 TI - Chlorhexidine in dental practice. PMID- 4217808 TI - Hepatitis and hepatitis-associated antigen (Au) in Upper Egypt. PMID- 4217810 TI - Side effects of IV fructose load in diabetics. PMID- 4217809 TI - Oral management of uncomplicated maturity onset diabetes. PMID- 4217811 TI - Immunologic relationship between the bactericidal fraction of neurotoxin and the protein from Salmonella typhimurium "S" endotoxin. PMID- 4217812 TI - The immunochemical investigations of endotoxins of asporulating gram negative rods (genus Sphaerophorus and Eggerthella). PMID- 4217814 TI - Fever and sleep cycle changes caused by bacterial products. PMID- 4217813 TI - Immunochemical and toxic properties of the lipopolysaccharides from highly and low virulent Pseudomonas aeruginosa strains. PMID- 4217815 TI - A clinical trial of reserpine--clopamide--dihydroergocristine in the treatment of hypertension. PMID- 4217817 TI - Six years experience with pelvic inflammatory disease. PMID- 4217816 TI - Some factors affecting the detection of long-acting thyroid stimulator protector using the McKenzie bioassay. PMID- 4217818 TI - Free fatty acids, diacyl- and triacylglycerols and total phospholipids in vertebrate retina: comparison with brain, choroid and plasma. PMID- 4217819 TI - Human placental lactogen levels in amniotic fluid in rhesus isoimmunization. PMID- 4217820 TI - The effect of copper deficiency on the mandibular joint and alveolar bone of pigs. PMID- 4217821 TI - Longitudinal studies in oral leukoplakias. PMID- 4217822 TI - The calcifying ghost cell odontogenic tumor - or the calcifying odontogenic cyst. PMID- 4217823 TI - Structure of antibodies. PMID- 4217824 TI - Lignans from Larrea divaricata. PMID- 4217825 TI - [Carcinoma of the nasopharynx. Experience of the Institute of Radiology of the University of Florence (author's transl)]. PMID- 4217827 TI - Modern radiation therapy of carcinoma of the prostate. PMID- 4217826 TI - [Diagnostic and therapeutic problems posed by cancer of the prostate (author's transl)]. PMID- 4217828 TI - [Problems in radiotherapy of cancer of the prostate]. PMID- 4217829 TI - [Treatment of cancers of the bladder by curietherapy]. PMID- 4217830 TI - [Local chemotherapy in vesical neoplasms]. PMID- 4217831 TI - The prevalence of long-term illness in a family practice. PMID- 4217832 TI - Calcium ions and control of the motility of sea urchin spermatozoa. PMID- 4217833 TI - The incidence of Brucella ovis infection in South African rams: a serological survey. PMID- 4217834 TI - Brucellosis in Rhodesian Wildlife. PMID- 4217835 TI - Anthrax in an African buffalo (Syncerus caffer) in the Kruger National Park. PMID- 4217836 TI - Antimicrobial effectiveness ofkanamycin, aminosidin, BB-K8, sisomicin, gentamicin and tobramycin combined with carbenicillin or cephalothin against gram-negative rods. PMID- 4217837 TI - Editorial: Monkeys, models, and midwives. PMID- 4217838 TI - Heteroagglutinins in human sera specific for erythrocytes of nonhuman primates. PMID- 4217839 TI - Recent developments of biomedical research in nonhuman primates. With a short historical review. PMID- 4217840 TI - Cholesterol gallstones in Aotus trivirgatus. PMID- 4217841 TI - Paramyosin of Caenorhabditis elegans. PMID- 4217842 TI - Chromosomes segregration and development in Caulobacter crescentus. PMID- 4217843 TI - Effect of glutaraldehyde and urea embedding on intracellular ionic elements. X ray microanalysis of skeletal muscle and myocardium. PMID- 4217844 TI - Structural variability of immunoglobulins. PMID- 4217845 TI - Ethnic characteristics of the kappa : lambda ratio of immunoglobulins in health and disease of the Japanes and Occidental. PMID- 4217846 TI - Single radial diffusion using catalase antibody as screening method of hypocatalasemia. PMID- 4217847 TI - Antigenic analyses of sequential isolates of Coxsackie A16 virus from 1964 to 1970 in Japan. PMID- 4217848 TI - [Discussion: current psychiatric care and legislation concerning mental patients]. PMID- 4217849 TI - [Legislation concerning confinement of mental patients and pressure exerted on psychiatric care]. PMID- 4217850 TI - [Regional mental health nursing and legislation concerning confinement of psychiatric patients]. PMID- 4217851 TI - [Changes necessary in the attitude of nurses- the problem of legislation concerning confinement of mental patients. A discussion]. PMID- 4217852 TI - [Sections of the legal code concerning confinement of mental patients and criticism by the legal, psychiatric and public health organizations]. PMID- 4217853 TI - [Case conference. A nursing plan for a patient with schizophrenia and delusions]. PMID- 4217854 TI - [Introduction of foreign literature and discussion: on "Preoperative assessment for postoperative evaluation"]. PMID- 4217855 TI - [Comparison of annual mortality in major disease categories]. PMID- 4217856 TI - [Introduction to human genetics. 11. Genetics and effects of drugs]. PMID- 4217858 TI - [Introduction to homeostasis. 11. Homeostasis and immunity]. PMID- 4217857 TI - [Environment and man. 8. Environmental pollution and its management (2)]. PMID- 4217859 TI - [Personality abnormalities. 8. Various types of abnormalities. (3)]. PMID- 4217860 TI - [Bedside nursing. Psychological impact of breast cancer and apprehension of the patient]. PMID- 4217861 TI - [Bedside nursing. Nursing of a tuberculosis patient unwilling to return home after an extended period of hospitalization]. PMID- 4217862 TI - [Bedside nursing. Nursing of a patient with cerebral hemorrhage associated with personality changes and aphasia]. PMID- 4217864 TI - [The theory of assistance; lessons in modern counseling. 11. A new horizon in interpersonal relations]. PMID- 4217863 TI - [Practice of nursing in the coronary care unit. 5. A case of myocardial infarct with persistent abdominal pain developing on the 4th day of hospitalization]. PMID- 4217865 TI - Effect of CaEDTA administration on urinary hydroxyproline excretion and skin wound healing in the rat. PMID- 4217866 TI - Healing of lined and unlined parasitic and nonparasitic flaps. PMID- 4217867 TI - [Antiseptics and disinfectants. Their correct use]. PMID- 4217868 TI - [Primary drug resistance in adult pulmonary tuberculosis]. PMID- 4217869 TI - [Detection and correction of nutritional deficiencies during aerobic culture of microorganisms]. PMID- 4217870 TI - [Incorporation of uridine-H3 in the macronuclear anlage of Stylonychia mytilus]. PMID- 4217872 TI - [Isolation of murein-free spheroplast ghosts from a strain of Escherichia coli K 12]. PMID- 4217871 TI - [Microbiological study of spheroplasts from pathogenic Pseudomonas produced by antibiosis at the cell wall and membrane levels]. PMID- 4217873 TI - Structural components of measles virus. PMID- 4217874 TI - Intracellular accumulation of measles virus nucleocapsid and envelope antigens. PMID- 4217875 TI - [Leptospirillum ferrooxidans and characteristics of its autotrophic growth]. PMID- 4217877 TI - [Fluorescence spectra of polynucleotide peptide complexes isolated from algae]. PMID- 4217876 TI - [Phenol oxidase activity of chromogenic actinomycetes]. PMID- 4217879 TI - [Selection of microorganisms synthesizing extracellular enzymes with lipoprotein lipase activity]. PMID- 4217878 TI - [Physiological and biochemical characteristics of Spirulina platensis cultures]. PMID- 4217880 TI - [Taxonomy of Methanosarcina]. PMID- 4217881 TI - [Effect of dynamic factors of space flight on the survival of microorganisms and their iron-porphyrin enzymes]. PMID- 4217883 TI - The use of Microstix in the diagnosis of urinary tract infections. PMID- 4217882 TI - [Ribulose diphosphate and phosphopyruvate carboxylase activity in phototropic bacteria]. PMID- 4217884 TI - Diuretics, cardiac failure and potassium depletion: a rational approach. PMID- 4217885 TI - Surgical drapes and their permeability to bacteria. PMID- 4217886 TI - [Correlations between the selectivity index, the histological picture and therapeutic response in the infantile nephrotic syndrome]. PMID- 4217888 TI - [Progressive myoclonus epilepsy in two siblings and 5 cases with dyssynergia cerebellaris myoclonica in several generations of a kinship, a clinical and genetic study]. PMID- 4217889 TI - Single-drug therapy in ovarian cancer. PMID- 4217887 TI - Renaturation of denatured DNA in NaI gradients. PMID- 4217890 TI - Identification and typing of viruses and detection of antiviral antibodies by counterimmunoelectrophoresis. PMID- 4217891 TI - F antigen. I. Purification and polymorphism. PMID- 4217892 TI - [Dynamics of the blood serotonin content in pregnancy and labor in isoimmunized women]. PMID- 4217893 TI - [Further study of the 20-ketosteroid reduction reactions of Bacillus megaterium strain VNIKhFI-1 (All-Union Chemistry and Pharmaceuticals Research Institute)]. PMID- 4217894 TI - [Use of miscleron on diabetes mellitus patients with peripheral circulatory disorders]. PMID- 4217895 TI - [Dynamics of the change in the rat hypothalamo-hypophyseo-thyroid system after unilateral thyroidectomy]. PMID- 4217896 TI - Laser damage to ocular tissues. PMID- 4217897 TI - Ocular examination of laser workers and investigation of accidents. PMID- 4217898 TI - Laser safety codes. PMID- 4217899 TI - Physiological actions of prolactin. PMID- 4217900 TI - Radioimmunoassay of human prolactin. PMID- 4217901 TI - Prolactin studies in normal subjects. PMID- 4217902 TI - Systemic sarcoidosis with massive hepatic involvement. PMID- 4217903 TI - Immunological and clinical findings in workers and consumers exposed to enzymes of Bacillus subtilis. PMID- 4217904 TI - Clinical findings in workers exposed to the enzymes of Bacillus subtilis. PMID- 4217905 TI - A technique of after-loading: high dose-rates. PMID- 4217906 TI - Radiotherapy of testicular tumours. PMID- 4217907 TI - Letter: The calculation of ionization chamber collection efficiency for pulsed beams. PMID- 4217908 TI - Immunodeficiency: enigmas and speculations. PMID- 4217909 TI - Surface immunoglobulins on human lymphoid cells. PMID- 4217910 TI - Therapeutic uses of transfer factor. PMID- 4217911 TI - Toxicity of propellants. PMID- 4217912 TI - [Studies on wild reservoirs and vectors of Trypanosoma cruzi. L: Synonym of Trypanosoma deanei Coutinho and Pattolli, 1964 in Trypanosoma cruzi Chagas, 1909]. PMID- 4217913 TI - [Unpublished aspects of the behavior of marmosets of the genus Callithrix (Callithricidae, Primates]. PMID- 4217915 TI - [Secretion granules of the accessory lacrimal gland of the monkey (Cebus sp)]. PMID- 4217914 TI - [Proof of the developmental stages of Rhodnius neglectus by susceptibility to Trypanosoma cruzi infection]. PMID- 4217916 TI - The influence of endocrine and exocrine pancreas on the carbonic anhydrase activity of the rat salivary glands. PMID- 4217917 TI - [Cyclopia: clinical, radiological, anatomo-pathological and genetic study]. PMID- 4217918 TI - The use of the antiglobulin test in the diagnosis of bovine brucellosis. PMID- 4217919 TI - Parenteral infection of laboratory animals with metacercariae of Fasciola hepatica. PMID- 4217920 TI - Duration of serological response to the indirect fluorescent antibody test of cattle recovered from Theileria parva infection. PMID- 4217921 TI - The detection of tuberculin-sensitive lymphocytes from bovine blood by uptake of radio-labelled nucleosides. PMID- 4217922 TI - Natural resistance to infection in the newborn sheep: competence of local and and systemic defences in normally-sukled and colostrum-deprived lambs. PMID- 4217924 TI - Changes in the serum immunoglobulin levels of colostrum-fed calves during the first 12 weeks postpartum. PMID- 4217923 TI - Distribution of Brucella antibody among immunoglobulin classes and a low molecular weight antibody fraction in serum and whey of cattle. PMID- 4217925 TI - [Malignant neurofibromatosis (report of a case of prolonged survival)]. PMID- 4217926 TI - [Radiological examination of the stomach in various neuropsychological diseases and syndromes. Considerations on morpho-functional changes]. PMID- 4217927 TI - [Modified lowenstein-jensen medium for isolation of the koch bacillus from paucibacillary sputum]. PMID- 4217928 TI - [Recent Anglo-Saxon works on chrysotherapy of rehumatoid arthritis]. PMID- 4217929 TI - [Results after 3 to 5 years of treatment of 219 cases of Parkinson's syndrome treated by L-Dopa and an L-Dopa -decarboxylase inhibitor combination]. PMID- 4217931 TI - [Neonatal hemolytic jaundice caused by anti-D reacting preferentially in an enzyme medium]. PMID- 4217930 TI - [Diffuse gliomatosis of the leptomeninges and tuber oligodendrioma]. PMID- 4217932 TI - [Rh nul phenotype]. PMID- 4217933 TI - [Morphology and histochemistry of early injuries of rat myocardium including proteins and their functional groups]. PMID- 4217934 TI - [In vitro effects of vinblastine sulfate, methotrexate and alkeran on human chromosomes]. PMID- 4217936 TI - [Radiological assessment of the effects of increased intrajejunal pressure on the portal vein bed and liver in dogs in experimentally induced small bowel obstruction]. PMID- 4217935 TI - [Angiographic evaluation of small arteries of small arteries following the use of patch grafts]. PMID- 4217937 TI - The effect of stimulation of central end of the vagus on the phrenic activity after strichnine and picroxin. PMID- 4217938 TI - [Role of collagen in the pathogenesis of rheumatoid arthritis]. PMID- 4217939 TI - Morphological examinations of pancreatic tissue in dog with acute pancreatitis. PMID- 4217940 TI - Differential thermal analysis of oral and palmar epithelium. PMID- 4217941 TI - Deposits of immunoglobulins and complement in oral lupus erythematosus. PMID- 4217942 TI - A mutant of Bacillus subtilis with impaired ability for recombination and reduced activity of the enzyme ATP-dependent deoxyribonuclease. PMID- 4217943 TI - Distribution of defective chromosomes in human cells after treatment with chemical mutagens in vitro and in vivo. PMID- 4217944 TI - [Genesis of the human cyclops]. PMID- 4217945 TI - [Dosimetry of whole-body irradiation with electrons in the management of mycosis fungoides]. PMID- 4217947 TI - [Therapy or custody]. PMID- 4217946 TI - Calibration and measurement of potassium-40 with a whole-body counter. PMID- 4217948 TI - Transport of materials in the suctorian tentacle. PMID- 4217949 TI - Pathways of nucleocytoplasmic translocation of ribonucleoproteins. PMID- 4217950 TI - [Mechanism of action of cytostatic agents in rheumatoid arthritis]. PMID- 4217951 TI - [Combined administration of obzidan and sustak in the treatment of patients with chronic coronary insufficiency]. PMID- 4217952 TI - [Change in the phase structure of the cardiac cycle (according to ultrasonic Doppler cardiogram data) during the euphyllin and nitroglycerin tests on bronchial asthma and chronic pneumonia patients]. PMID- 4217953 TI - [Intravital histopathological changes in the gastric mucosa and the activity of certain cytoplasmic enzymes (cholinesterase, monoamine oxidase, histaminase) and acetylcholine in peptic ulcer and chronic gastritis]. PMID- 4217954 TI - Electronic platelet counting after isopycnic differential centrifugation a simple rapid and accurate method. AB - A semi-automatized platelet counting procedure with the use of a Coulter Counter is described. Its originality consists in providing an electronic method of counting of the platelets after a differential centrifugation of the blood sample previously diluted with a hypertonic NaCl solution (density 1.053) which is isopycnic to platelet density. This procedure allows elimination of red and white cells without loss of platelets in the supernatant. The final platelet number can be calculated without further corrections. The method is quick and does not require specially skilled technicians. A single technician can perform 40 counts in one hour. The reproductibility of the method is excellent and the coefficient of variation 2,4%. The accuracy and feasibility of the method is also sustained by two years' experience in an haematological routine laboratory. PMID- 4217956 TI - [Restoration of the biliary tract]. PMID- 4217955 TI - Fibrinogen Valencia. A new case of congenital dysfibrinogenemia. PMID- 4217957 TI - [Problem of arterial replacement an experimental and clinical report (author's transl)]. PMID- 4217958 TI - [Skin reactions caused by irradiation]. PMID- 4217959 TI - [Nutrition of the cancer patient]. PMID- 4217960 TI - Separation and characterization of immunoglobulin classes of anti-salmon sperm deoxyribonucleic acid antibodies in rabbits. PMID- 4217961 TI - [Study of rabbit serum albumin in inflammation]. PMID- 4217962 TI - [Detection of dipeptidases in certain microbial proteolytic complexes]. PMID- 4217963 TI - [Bacteriological study of the lumen and wall of the vermiform sppendix in acute appendicitis]. PMID- 4217964 TI - Regeneration and functional recovery of canine intestinal mucosa following injury caused by formalin. PMID- 4217965 TI - The ultrastructural effects of aflatoxin B1 in the rat pancreas. PMID- 4217966 TI - Aurosomes in rabbit articular cartilage. PMID- 4217967 TI - [Studies on the duration of the nuclear DNA synthesis in the buccal mucosa of adult male rats. I Comparative evaluation of two autoradiographic methods in vivo (author's transl.)]. PMID- 4217968 TI - [Studies on the durationof the nuclear DNA synthesis in the buccal mucosa of adult male rats. II. Autoradiographic investigations in vitro (author's transl.)]. PMID- 4217969 TI - A scanning electron microscope study of the glomerulus of normal and nephritic rabbits. PMID- 4217970 TI - Immunofluorescent studies on the occurrence of cathepsin B1 at tumor cell surfaces. PMID- 4217971 TI - From studies on the parasitic Ciliata invading plant-feeding species of fish in ponds. PMID- 4217972 TI - Nutrition after injury. PMID- 4217973 TI - [Hypothesis on the phylogeny of vertebrate coccidiomorpha (author's transl)]. PMID- 4217976 TI - The economics of human parasitic infections. PMID- 4217977 TI - [Determination of the right-to-left shunt in cyanotic heart defects through differentiation of pulmonary and rest-body activities in whole-body scintigraphy following administration of 99mTc-labeled albumin microspheres]. PMID- 4217978 TI - [Biochemical results in Fabry's disease]. PMID- 4217974 TI - Advances in the biology of sporozoa. PMID- 4217979 TI - [Influencing of blood sugar, serum insulin level and nonesterified fatty acids during continuous feeding following orally administered sulfonylurea compounds ARDF 26 and glibenclamide]. PMID- 4217980 TI - [Nonspecific TRH-effect on HGH-secretion in patients with chronic kidney insufficiency]. PMID- 4217981 TI - [Endocrine opthalmopathy-- new physiopathological viewpoints through the determination of T3, T4 and TSH following TRH stimulation]. PMID- 4217982 TI - [Comparison of prothrombin activity and concentration in various liver conditions]. PMID- 4217975 TI - Advances in the immunodiagnosis of parasitic infections. PMID- 4217983 TI - [Disease observations in hematologic system diseases (leukemia Waldenstrom's disease) and immunologic deficiencies using B- and T-cell specific markers]. PMID- 4217984 TI - [Pharmacokinetics and therapeutic experiences with a new cephalosporin derivative: cefazoline]. PMID- 4217985 TI - [Polychlorated biphenyls and cytochrome P-450]. PMID- 4217986 TI - [Detection of circulating immune complexes in patients with lupus erythematosus, viral hepatitis and rheumatoid arthritis using radioactive marked C1q]. PMID- 4217987 TI - [Regression of mastocytoma in mice following virus treatment]. PMID- 4217988 TI - [Experiences with procarbazine therapy in Waldenstrom's disease]. PMID- 4217989 TI - [Hypertension during the fertile age in the female]. PMID- 4217990 TI - [Hemodynamic effects of long-term saluretic therapy of hypertension]. PMID- 4217991 TI - [Distribution patterns of Australia-antigen subtypes D and Y in liver diseases]. PMID- 4217992 TI - [Uric acid production in the human liver during parenteral fructose administration]. PMID- 4217993 TI - [Intermittent long-term dialysis in the light of 10-year experience]. PMID- 4217994 TI - [Diagnosis and therapy of iron deficiency in long-term dialysis patients]. PMID- 4217995 TI - [Serum gastrin level and gastric juice secretion in chronic hemodialysis patients and its effect on them by changing ionized serum calcium]. PMID- 4217996 TI - [Dynamics of insulin secretion in terminal kidney failure and during chronic, intermittent dialysis treatment]. PMID- 4217997 TI - [Intracellular acid-base equilibrium in chronically dialized patients]. PMID- 4217998 TI - [Correlation between responses to spatial and optic cues during differentiation]. PMID- 4217999 TI - [Development of sexual dimorphism as an expression of gene Est-6 in the ontogenesis of Drosophila melanogaster and Drosophila simulans]. PMID- 4218000 TI - Australia antigen (Au(1), HAA, HABg) in expatriates living in Ibadan, Nigeria. PMID- 4218002 TI - [Importance of bacteriological findings in the urethral smears for the diagnosis of prostat vesiculitis]. PMID- 4218001 TI - [Importance of the infusion urogram in neurogenic bladder]. PMID- 4218004 TI - [Clinical nursing care for aged and long-term patients]. PMID- 4218003 TI - [Various organizational problems in nursing care for elderly and chronic patients in hospitals]. PMID- 4218005 TI - [Improvement of the methods of planning of the development of the material basis of public health of the RSFSR]. PMID- 4218006 TI - [Peripheral osteosynthesis - indications and technics]. PMID- 4218007 TI - [Late results of the conservative therapy of malleolar fractures and the surgical treatment of fork splintering by Cedell's clamping of the syndesmoses]. PMID- 4218008 TI - [Preparative separation of toxin and prototoxin from CL. botulinum type B cells]. PMID- 4218009 TI - [Mixed infections caused by Prowazek rickettsiae and tsutsugamushi rickettsiae]. PMID- 4218010 TI - [Use of phage typing for deciphering group illness with diphtheria in closed collectives for adolescents]. PMID- 4218011 TI - [Distribution of tetanus toxoids, sorbed on aluminum phosphate gel and labeled with P32, in the bodies of animals]. PMID- 4218012 TI - [Construction of new types of chemical vaccines for prevention of intestinal infections and problems with their qualitative evaluation. I. Current aspects of construction and improving and quality of chemical vaccines]. PMID- 4218014 TI - [A method of studying the toxicity of meningococci in live models]. PMID- 4218013 TI - [The role of colicins in infectious pathology (review of the literature)]. PMID- 4218016 TI - [Nucleotide composition of the DNA of Listeria]. PMID- 4218015 TI - [Characteristics of histaminergic changes in the dynamics of the primary immune response]. PMID- 4218017 TI - [Immunity indices in meningococcal infections]. PMID- 4218018 TI - [Antibody formation during immunization of animals with antigens from Mycobacterium tuberculosis, L-forms and their revertants]. PMID- 4218019 TI - [Change in convertant phagotypes of non-toxigenic C. diphtheriae type gravis following infection by tox+-viruses]. PMID- 4218020 TI - [Histopathology of tsutsugamushi fever in mice]. PMID- 4218021 TI - [Extraction of the exotoxin of anthrax vaccinal strain STI-1]. PMID- 4218022 TI - [The effect of horse serum on bacterial sensitivity to penicillins]. PMID- 4218023 TI - [Foot-and-mouth disease in man]. PMID- 4218024 TI - [Comparative findings concerning the effect of chlorine and ozone on the microflora of water]. PMID- 4218025 TI - [A comparative study of several current methods of rapid Prowazek rickettsia detection in the vector]. PMID- 4218026 TI - [Staphylococcal enterotoxins and methods of detecting them (review of the literature)]. PMID- 4218027 TI - [The agent of melioidosis (review of the literature)]. PMID- 4218028 TI - [Purification of protective staphylococcal antigen]. PMID- 4218030 TI - [Location of ferritin labeled antibodies within the bacterial cell]. PMID- 4218029 TI - [Immune ascitic fluids to group A menigococci]. PMID- 4218031 TI - [Common antigens, sensitive to trypsin in hydrochloric acid extracts, obtained from group A streptococci of different types]. PMID- 4218032 TI - [Morphological characteristics verus the physiological and biochemical regularities of the activity of microoroganisms during periodic and continuous cultivation (literature review)]. PMID- 4218034 TI - [P-antigen of the causative agent of tularemia]. PMID- 4218033 TI - [Role of intracellular parasitization by Shigella in the pathogenesis of dysentery]. PMID- 4218035 TI - [The role of H-antigen in postvaccinal immunity against typhoid and paratyphoid]. PMID- 4218036 TI - [A study of patterns of tsutsugamushi rickettsiae multiplication in different cell systems for the purpose of obtaining antigens for the complement fixation test]. PMID- 4218037 TI - [A comparison of the sensitivity of nutrient media for intact microorganims and following exposure to substerilizing doses of different sterilizing agents]. PMID- 4218038 TI - [Decarboxylase activity of strains of Bac. cereus of different origin]. PMID- 4218039 TI - [Experience in uncovering the etiology of dysentery-like diseases]. PMID- 4218041 TI - [Salmonella as one of the indices of biological water pollution of open reservoirs]. PMID- 4218040 TI - [Microbiologic characteristics of meningococcal infections in Moscow during years of a periodic rise in incidence (1968--1971)]. PMID- 4218042 TI - [Plague, tularemia and anthrax immunization with associated di- and trivaccines using a jet injector. I]. PMID- 4218043 TI - [Benign brain tumors with a remitting course]. PMID- 4218044 TI - [Tumors of the spinal cord in children]. PMID- 4218045 TI - [Some findings from a clinico-immunologic study of patients at remote periods after cranio-cerebral trauma]. PMID- 4218046 TI - [Jacksonian epileptiform seizures in patients with cerebral hemorrhage and hypertension]. PMID- 4218047 TI - [Comparative characteristics of epileptic seizures in patients with unifocal and multifocal epilepsy]. PMID- 4218048 TI - [Periods of development and quasi-stability in the structure of petit mal paroxysms]. PMID- 4218049 TI - Inhibition of the diuretic action of glibenclamide by clofibrate, carbamazepine and 1-deamino-8-d-arginine-vasopressin (DDAVP) in patients with pituitary diabetes insipidus. PMID- 4218051 TI - Proceedings: Effects of centrophenoxine and palmitoylethanolamide in rats with early protein and calorie malnutrition. I. Neurological tests. PMID- 4218050 TI - Studies of the actions of thiols, lithium ions and insulin on carbohydrate metabolism of the isolated rat diaphragm. PMID- 4218052 TI - Proceedings: The effects of centrophenoxine and palmitoylethanolamide in rats with early protein and calorie malnutrition. II. Somatic and biochemical parameters. PMID- 4218054 TI - A serum factor influencing the physiological activity of thyrotropin-releasing hormone (TRH) I. Studies with human serum. PMID- 4218053 TI - Transfer of TRH through the placenta and metabolism in the fetus of the guinea pig. PMID- 4218055 TI - A serum factor influencing the physiological activity of thyrotropin-releasing hormone (TRH). II. Studies with rat serum in vivo and in vitro. PMID- 4218056 TI - Autoradiographic - histochemical demonstration of tyrosinase activity in melanin forming tissues of mammals. PMID- 4218057 TI - [Clinical and neuro-endocrinological study of trh in melancholia]. PMID- 4218058 TI - Vascular supply of the rat medial basal hypothalamus and development of vascular connections between this region and the rest of the brain following deafferentation of the former area. PMID- 4218059 TI - "Monoclonal" IgM-gammopathy with two different light-chain types of protein (Bence-Jones I and II). PMID- 4218060 TI - Experimental chemotherapy of Schistosomiasis mansoni. PMID- 4218061 TI - [Experimental pseudomonal keratitis in mice. The effect of corticosteroid]. PMID- 4218062 TI - Corynebacterium pyrogenes; a biochemical and serological study. PMID- 4218063 TI - Estrone and progesterone plasma levels of normal cows and cows with parturient paresis. PMID- 4218064 TI - Serum levels of the immunoglobulins IgG and IgG(T) in horses. PMID- 4218066 TI - [Spectrophotometric and serological analysis of the amniotic fluid in the Rh sensitization of pregnant women]. PMID- 4218067 TI - [Plasmapheresis as a method of lowering the degree of Rh-sensitivity in pregnant women]. PMID- 4218065 TI - The occurrence of antibodies against staphylococcal deoxyribonucleases in blood sera from different species. PMID- 4218068 TI - Evaluation of antigen-coated red cells for detection of serum hepatitis antigen and antibody. PMID- 4218069 TI - [Study of the antigenic makeup of some oxytetracycline producers using the precipitation in agar reaction]. PMID- 4218070 TI - [Comparative study of the levels of erythromycin resistance in Staphylococcus according to data from agar diffusion and serial dilution methods]. PMID- 4218071 TI - [Semisynthetic penicillins with a substituted neopentyl side chain]. PMID- 4218072 TI - Morphological alterations of Pseudomonas aeruginosa by ticarcillin: a scanning electron microscope study. AB - Pseudomonas aeruginosa was exposed to 0.1, 1.0, 10, 100, and 1,000 times the minimal inhibitory concentration of ticarcillin in vitro and subsequently examined with the scanning electron microscope. The morphological alterations observed were filamentation, mid-cell defects, and spheroplast formation, and these alterations were dependent upon the drug concentration. PMID- 4218073 TI - [Immunological aspects of Flajani-Graves-Basedow disease]. PMID- 4218074 TI - [Case of hyperosmolar coma caused by L-gulitol]. PMID- 4218075 TI - [Complete left branch block with strong left axial deviation of the qrs. ii. Anatomical study]. PMID- 4218076 TI - [Bilateral branch block: study of the electrocardiographic aspects and of the anatomic and electric correlations in 100 cases with major histological lesions of the 2 branches of the bundle of his. i. Study of the electrocardiographic aspects]. PMID- 4218077 TI - [Bilateral branch block: study of electrocardiographic aspects and of the anatomic and electric correlations in 100 cases with major histological lesions of the bundle of his. II. Study of the anatomic and electric correlations]. PMID- 4218078 TI - [Complete left branch block with strong left axial deviation of the qrs. i. Clinical study]. PMID- 4218079 TI - [The electrical aspects and cardiac risks of therapeutic hyperkalemia]. PMID- 4218080 TI - [Hemodynamic effects of auricular stimulation: unusual problem of angina patients with normal coronary vessels]. PMID- 4218082 TI - [Study of renal venous flow with the thermodilution method in the course of secondary arterial hypertension]. PMID- 4218081 TI - [Results of multivalvular replacement surgery]. PMID- 4218083 TI - [Results of an echographic visualization study of cardiac structures]. PMID- 4218084 TI - [A new technic: study by echography of the contractile function of the myocardium]. PMID- 4218085 TI - [Functional rehabilitation of patients with valve prostheses]. PMID- 4218086 TI - [Non-surgical extraction of a catheter which migrated into the pulmonary artery]. PMID- 4218087 TI - Formation of protoplasts in Azotobacter vinelandii. PMID- 4218088 TI - Intoxication, detoxication and copper-storage of central nervous tissue at different external Cu(II)-concentrations. PMID- 4218089 TI - Use of a triple layer enzyme method as an alternative to immunofluorescence for the detection of tissue antigens. PMID- 4218090 TI - [Studies on the survival time of Sarcocystis in the meat of slaughter animals]. PMID- 4218091 TI - Rapid titration of dengue virus type 4 infectivity by counting fluorescent foci. PMID- 4218092 TI - Purification of human placental alkaline phosphatase. Salt effects in affinity chromatography. AB - Human placental alkaline phosphatase was chromatographed on Sepharose derivatives of d- and l-phenylalanine, l-leucine, glycine, aniline and p-aminobenzoic acid in high concentrations of (NH(4))(2)SO(4). Retention on these columns was greatest at the highest concentrations of (NH(4))(2)SO(4). By using decreasing concentrations and changing the types of salts, elution was effected from each of the columns. The (NH(4))(2)SO(4)-mediated retention appeared to be related to the hydrophobic character of the substituted Sepharose, rather than to any specific binding site of the enzyme. It is suggested that this provides a way of controlling hydrophobic affinity chromatography. By use of chromatography on l phenylalanine-Sepharose and of DEAE-Sephadex chromatography in the presence of Triton X-100 detergent, a preparation of highly purified (1000-fold) human placental alkaline phosphatase was obtained in 22% yield. PMID- 4218093 TI - An electron-capture gas-liquid-chromatographic method for the determination of prostaglandin F2alpha in biological fluids. AB - A sensitive electron-capture gas-liquid-chromatographic method for the determination of sub-nanogram quantities of prostaglandin F(2alpha) was developed. The method is based on the sub-microgram scale conversion of the prostaglandin into the electron-capturing pentafluorobenzyl ester, and analysis of the latter as the tris-trimethylsilyl ether. The lower limit of detection was 12.5pg of the ester injected ;on-column' as the silylated product. The method was successfully applied to the determination of prostaglandin F(2alpha) in monkey plasma. The specificity of the analytical procedure was increased by incorporating a thin-layer chromatographic fractionation before gas-liquid chromatography. The utility of the analytical methodology developed was demonstrated by its application to the determination of plasma concentrations of intact prostaglandin F(2alpha) in a Rhesus monkey, after subcutaneous administration of a single dose of prostaglandin F(2alpha). The electron-capture gas-liquid-chromatographic assay is compared with the radioimmunoassay and the gas-liquid-chromatographic-mass-spectrometry assay for the determination of prostaglandin F(2alpha). PMID- 4218094 TI - Thermal inactivation studies of normal and variant human erythrocyte carbonic anhydrases by using a sulphonamide-binding assay. AB - Heat-inactivation studies were carried out on the two primary erythrocyte carbonic anhydrase isoenzymes, CA I and CA II, and the secondary isoenzyme of CA I, CA I (+1). In addition, two genetic variants of human isoenzyme CA I, CA Id Michigan (100 Thr-->Lys) and CA If London (102 Glu-->Lys), and one variant of isoenzyme CA II, CA IIh (251 Asn-->Asp), were similarly analysed. The first-order rate constants and Arrhenius plots for these six enzyme forms showed that (1) isoenzyme CA II is more heat-stable than CA I, (2) isoenzyme CA I (+1) is less heat-stable than CA I, (3) the variants CA IIh and CA If London are less heat stable than the normal enzymes, and (4) isoenzyme CA Id Michigan is more heat stable than normal CA I. From the values of the slopes of the Arrhenius plots, the energy of activation (E(a)) for each isoenzyme and isoenzyme variant was determined, and the following thermodynamic activation parameters were calculated at 55 degrees C: the free energy of activation (DeltaG(double dagger)), the activation enthalpy (DeltaH(double dagger)) and the activation entropy (DeltaS(double dagger)). The DeltaG(double dagger) for the enzymes shows a relative constancy with compensating variation in DeltaH(double dagger) and DeltaS(double dagger). When the values for DeltaH(double dagger) are plotted against DeltaS(double dagger), an increase in DeltaH(double dagger) involves a concomitant increase in DeltaS(double dagger). PMID- 4218095 TI - Chemical and immunochemical characteristics of tropomyosins from striated and smooth muscle. AB - 1. On electrophoresis in dissociating conditions the tropomyosins isolated from skeletal muscles of mammalian, avian and amphibian species migrated as two components. These were comparable with the alpha and beta subunits of tropomyosin present in rabbit skeletal muscle. 2. The alpha and beta components of all skeletal-muscle tropomyosins contained 1 and 2 residues of cysteine per 34000g respectively. 3. The ratio of the amounts of alpha and beta subunit present in skeletal muscle tropomyosins was characteristic for the muscle type. Muscle consisting of slow red fibres contained a greater proportion of beta-tropomyosin than muscles consisting predominantly of white fast fibres. 4. Mammalian and avian cardiac muscle tropomyosins consisted of alpha-tropomyosin only. 5. Mammalian and avian smooth-muscle tropomyosins differed both chemically and immunologically from striated-muscle tropomyosins. 6. Antibody raised against rabbit skeletal alpha-tropomyosin was species non-specific, reacting with all other striated muscle alpha-tropomyosin subunits tested. 7. Antibody raised against rabbit skeletal beta-tropomyosin subunit was species-specific. PMID- 4218096 TI - Comparison of the biliproteins from two strains of the thermophilic cyanophyte Synechococcus lividus. AB - C-Phycocyanins from two thermophilic strains of Synechococcus lividus that grow within different temperature ranges have been shown to be unalike. The aggregation ability of these two C-phycocyanins in sedimentation-velocity experiments varied dramatically. Surprisingly, the aggregation properties of mesophilic C-phycocyanins were found to lie between those of the two thermophilic proteins. Under identical conditions at pH7.0, one thermophilic protein (Sy I) was composed of 17S and larger aggregates, whereas the other (Sy III) was an almost homogeneous 6S aggregate. Mesophilic C-phycocyanins have a mixture of 6S, 11S and less stable 17S aggregates under these conditions. Amino acid analysis, absorption spectra, immunochemistry and fluorescence polarization all indicated differences in the composition and properties of the thermophilic proteins, which suggest that they have different modes of adaptation to very high temperatures. Allophycocyanins from the two strains of S. lividus were also purified and studied, but unlike the C-phycocyanins no major differences were found between them. Allophycocyanin was homogeneous at pH6.0, with a sedimentation coefficient of 5.54S and mol.wt. 1.03x10(5), as determined by sedimentation-equilibrium measurements. PMID- 4218097 TI - A more detailed study of bile salt evolution, including techniques for small scale identification and their application to amphibian biles. AB - 1. Methods have been developed for the isolation and identification of small amounts of bile salts and of bile acids and alcohols obtained by solvolysis. These methods involve preparative and analytical t.l.c., purification on columns of protonated Al(2)O(3) and Sephadex LH-20 and also g.l.c.-mass spectroscopy of solvolysis products. 2. Application to 29 species of frogs and toads has confirmed the constancy of bile salt patterns in a single species, including colour phases in two instances, and has revealed great variations between different species in some genera (e.g. Rana, Ptychadena) and little difference between widely distributed species in others (e.g. Bufo). 3. Taxonomic deductions should be made with caution and with regard to the physiological significance of the biochemical character considered. The molecular differences found might be interpreted as indicating variations in the rate of evolution. PMID- 4218098 TI - Pyruvate and nitrogenase activity in cell-free extracts of the blue-green alga Anabaena cylindrica. PMID- 4218099 TI - The amino acid sequence of the C- terminal cyanogen bromide peptide of human J chain. PMID- 4218100 TI - Morquio's syndrome: deficiency of a chondroitin sulfate N-acetylhexosamine sulfate sulfatase. PMID- 4218101 TI - Amino acid sequence of Streptomyces griseus protease B, A MAJOR COMPONENT OF Pronase. PMID- 4218102 TI - Identification of several unique low molecular weight basic proteins in dormant spores of Bacillus megaterium and their degradation during spore germination. PMID- 4218103 TI - The occurrence of a transmethylation reaction not involving S-adenosylmethionine in the formation of ribothymidine in Bacillus subtilis transfer-RNA. PMID- 4218104 TI - Decarboxylation of long chain fatty acids to alkanes by cell free preparations of pea leaves (Pisum sativum). PMID- 4218105 TI - Proton Magnetic resonance observations of hydrogen exchange rates and secondary structure in algal ferredoxin. PMID- 4218106 TI - Crystallisation of purified thyroxine-binding alpha globulin. PMID- 4218107 TI - Deficiency of chondroitin sulfate N-acetylgalactosamine 4-sulfate sulfatase in Maroteaux-Lamy syndrome. PMID- 4218109 TI - [Status epilepticus]. PMID- 4218108 TI - Effect of silybin on the hepatic microsomal drug-metabolising enzyme system in the rat. PMID- 4218110 TI - [Comparative antigenic analysis of ascaris suum, ascaris lumbricoides, toxocara mystax and ascaridia galli by gel double diffusion and immunoelectrophoresis (author's transl)]. PMID- 4218111 TI - [Effects of endogenous male hormone on the skeletal and perineal muscles of growing rats]. PMID- 4218112 TI - [Effects of amphotericin B on the permeability of hydrosoluble and liposoluble non-electrolytes through the urinary bladder of some amphibia]. PMID- 4218113 TI - The effect of sex difference on iron exchange in the rat. PMID- 4218114 TI - Ocular histoplasmosis syndrome in the United Kingdom. PMID- 4218116 TI - A comparative examination of amphibian sperm proteolytic activity. PMID- 4218115 TI - Studies on the radiation-induced dissociation and reassociation of polysomes in Tetrahymena pyriformis. PMID- 4218117 TI - Machine for the automatic washing of red blood cells and its use in the assay of anti-D antibody. PMID- 4218118 TI - Immunosuppression and experimental tuberculosis. II. The effects of immunosuppressive agents and antilymphocyte serum on the organ dissemination of mycobacteria and on the development of specific delayed hypersensitivity. PMID- 4218119 TI - Determination of pentachlorophenol and chlorobiphenylols in biological samples. PMID- 4218120 TI - Interactions of PCBs, DDT and DDE in a marine diatom. PMID- 4218121 TI - Co-carcinogenic effect of DDT and PCB feeding on methylcholanthrene-induced chemical carcinogenesis. PMID- 4218123 TI - Clinical and EEG studies of prisoners charged with murder. PMID- 4218122 TI - PCB residues in plankton and sediment in the southwestern coast of Finland. PMID- 4218124 TI - [Malformations in the eye region based on autosomal aberrations]. PMID- 4218125 TI - The potential of coenzyme Q 10 (NSC-140865) in cancer treatment. PMID- 4218126 TI - Antigen binding to lymphoid cells from unimmunized mice: high frequency of beta galactosidase binding cells at optimal conditions. PMID- 4218127 TI - Kinetics of B cell memory development during a thymus "independent" immune response. PMID- 4218128 TI - Acquired cellular immunity: extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages. PMID- 4218129 TI - Observations on migration inhibition of sensitized peritoneal exudate cells as a function of time. PMID- 4218130 TI - Immunoglobulin on activated T cells detected by indirect immunofluorescence. PMID- 4218131 TI - Cooperation of three lymphoid cells in allograft rejection. PMID- 4218133 TI - In vitro suppression ofimmunoglobulin allotype synthesis by Fab and F(ab')2 fragments of anti-allotype antibody. PMID- 4218132 TI - Characterization of contrasensitizing antibodies. PMID- 4218134 TI - Total parenteral nutrition. Experience with 180 patients. PMID- 4218136 TI - [Therapeutic studies of male gonococcal infections in the urban environment of Dakar]. PMID- 4218135 TI - [Parenteral hyperalimentation: its renal repercussions]. PMID- 4218137 TI - Immunology of Chagas' disease. AB - After reviewing present knowledge of the morphology, multiplication, and transmission of Trypanosoma cruzi, this Memorandum discusses the animal models that may be of value in understanding the immune mechanisms operating in Chagas' disease. The role of both circulating antibody and cell-mediated immunity in protection against the parasite is discussed, together with the possibility that immunopathological mechanisms may be responsible for some of the lesions found in patients with Chagas' disease. The immunodiagnostic methods at present available are also reviewed, and the possibility of producing a vaccine for human use is considered in the light of recent findings in experimental animals. A series of recommendations for further research is included. PMID- 4218138 TI - Antigenic variation in current influenza A viruses: evidence for a high frequency of antigenic 'drift' for the Hong Kong virus. AB - A new antigenic variant of the Hong Kong (H3N2) subtype of influenzavirus type A is described. The variant, A/Port Chalmers/1/73 (H3N2), was first isolated in Australasia in the autumn of 1973 and subsequently became the predominant influenza A variant in most areas of the world, replacing the previously prevalent strain A/England/42/72 (H3N2). The 1973 variant shows antigenic differences from former Hong Kong variants in both haemagglutinin and neuraminidase antigens. The application of immuno-double-diffusion tests and single-radial-diffusion tests in the antigenic analysis of new variants of the influenzavirus is also described. It is emphasized that since new variants of the Hong Kong virus have appeared in the successive years 1971, 1972, and 1973, the annual frequency of antigenic "drift" for the Hong Kong virus is higher than was recorded for the "Asian" influenzavirus (H2N2) in the first 5 years of the latter's prevalence from 1957 to 1962, during which period little antigenic variation occurred. PMID- 4218139 TI - A simple technique for culturing tubercle bacilli. AB - Microscopy, traditionally used in peripheral health centres to diagnose tuberculosis, could be supplemented by sputum culture if sputum specimens were inoculated on suitable media and sent to intermediate or central laboratories to be incubated and read. To facilitate this procedure, the authors propose a simplified swab culture method and a modification of Ogawa's egg medium. PMID- 4218140 TI - "Steady-state" properties of the baroreceptor-heart rate reflex in essential hypertension in man. PMID- 4218142 TI - Physiology and treatment of hypoxia. PMID- 4218143 TI - Immunochemical investigation of the antigens of drug-resistant staphylococcal strains. PMID- 4218141 TI - Coronary haemodynamic effects of nifedipine (Bay a 1040) and glyceryl trinitrate in unanaesthetized dogs. PMID- 4218144 TI - Some aspects of methicillin-resistance of Staphylococcus aureus. PMID- 4218145 TI - In vitro effects of staphylococcal alpha and delta toxins on liver mitochondria. PMID- 4218146 TI - Staphylococcal hyaluronate lyase. PMID- 4218147 TI - Bacteriological control of dissemination of Staphylococcus aureus at an intensive care unit. PMID- 4218148 TI - Epidemiology of enterotoxic strains of Staphylococcus aureus. PMID- 4218149 TI - Serological types of enterotoxins produced by strains of Staphylococcus aureus isolated from feces. PMID- 4218150 TI - Structure and immunology of protein A. PMID- 4218151 TI - Effect of carbohydrates and related compounds on the long-term preservation of freeze-dried bacteria. PMID- 4218152 TI - Effect of individual ingredients of fortified skim milk as suspending media on survival of freeze-dried cells of Streptococcus lactis. PMID- 4218153 TI - Comparative trial of tinidazole and metronidazole in intestinal amebiasis. PMID- 4218154 TI - A double-blind comparison of phenylbutazone and aspirin in osteoarthritis. PMID- 4218156 TI - Comparison of migraleve and buclizine in prophylaxis of migraine. PMID- 4218155 TI - Migraleve in the prophylaxis of migraine. PMID- 4218157 TI - Sensitivity of Pseudomonas aeruginosa to carbenicillin: an evaluation of susceptibility testing after four years of clinical usage. PMID- 4218158 TI - Studies on immunodiagnosis of angiostrongyliasis. 5. Double immunodiffusion and counterelectrophoresis for detection of antibody in infected rat and human sera. PMID- 4218159 TI - Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis. PMID- 4218161 TI - Thyrotrophin-releasing hormone in diagnosis. PMID- 4218160 TI - The genes for ribosomal RNA in diploid and polytene chromosomes of Drosophila melanogaster. PMID- 4218162 TI - [Long-term or intermittent treatment of chronic bronchitis?]. PMID- 4218163 TI - [Ticarcillin: in-vitro activity and pharmacokinetics (author's transl)]. PMID- 4218164 TI - The dysmorphogenic potential of phenytoin: experimental observations. PMID- 4218165 TI - Neuropathy in mucopolysaccharidosis type 3. PMID- 4218166 TI - Metabolic aspects of methylcyclopentadienyl manganese tricarbonyl in rats. PMID- 4218167 TI - Biological fate of -103Pd in rats following different routes of exposure. PMID- 4218168 TI - Some effects of DDT and PCB on the hormonal system in the male mouse. PMID- 4218169 TI - Immunological studies on glutamate dehydrogenase from the cytoplasmatic fraction of rat liver. PMID- 4218170 TI - Immunoglobulin synthesis and glucose-6-phosphate dehydrogenase as cell markers in human lymphoblastoid cell lines. PMID- 4218171 TI - Ghost monolayers in the study of the modulation of transcription in cultures of CV1 fibroblasts. PMID- 4218172 TI - Ultrastructural detection of single-stranded DNA in rat liver nucleus by the electronmicroscopic immuno-peroxidase method. PMID- 4218173 TI - Partition coefficient of membrane particles in the fusion rosette. PMID- 4218174 TI - Stable nuclear RNA returns to post-division nuclei following release to the cytoplasm during mitosis. PMID- 4218175 TI - Induction of fertilization membrane by ionophore A23187 in sea urchin egg Paracentrotus lividus. PMID- 4218176 TI - Circadian rhythm in size and 3H-uridine incorporation of single puffs of Drosophila salivary glands in vitro. PMID- 4218177 TI - Mitogenic stimulation of human leukemic plasma cells. PMID- 4218178 TI - [Mechanism of action of antitubercular drugs]. PMID- 4218179 TI - The Bacillus Subtilis genome: replication-order and map-position discrepancies- evidence for a second origin. AB - Replication order to map position discrepancies have been documented in B. subtilis. The discrepancies were found to occur whenever the genome of B. subtilis was replicated under a variety of physiological conditions and in both 168 and W23 strains. The earliest replicating marker involved in these discrepancies was thr versus purB and aroA versus recA. A detailed linkage analysis of the ura to argA region was consistent with its being a continuous linkage group. This led to the conclusion that an origin for new starts at replication exists between recA and aroA. PMID- 4218180 TI - The ribosomes of Drosophila. II. Studies on intraspecific variation. AB - Electrophoretic comparisons of 40S and 55S ribosomal subunit proteins from 18 strains of Drosophila melanogaster revealed the virtual absence of allelic variation. More detailed two-dimensional studies on the large subunit proteins in 6 of the strains demonstrated additional complexity but still no interstrain variation. The significance of these results is discussed with respect to present estimates of genic heterozygosity in natural populations. PMID- 4218181 TI - Concurrent multiple paternity in natural and laboratory populations of Drosophila melanogaster. AB - Electrophoretic analysis of two or three linked enzyme loci in progenies of homozygous females from cage and natural populations demonstrates frequent concurrent multiple paternity in both cases. PMID- 4218182 TI - The genetic variance for viability and its components in a local population of Drosophila melanogaster. AB - Two hundred and ninety second chromosomes extracted from a natural population of Drosophila melanogaster were analyzed to estimate the genetic variance of viability and its components by means of a partial diallel cross (Design II of Comstock and Robinson 1952). The additive and dominance variances are estimated to be 0.009 and 0.0012. Using the dominance variance and the inbreeding depression, the effective number of overdominant loci contributing to the variance in viability is estimated to be very small, a dozen or less. Either the actual number of loci is small, or the distribution of viabilities is strongly skewed with a large majority of very weakly selected loci. The additive variance in viability appears to be too large to be accounted for by recurrent harmful mutants or by overdominant loci at equilibrium with various genetic parameters estimated independently. The excess might be due to frequency-dependent selection, to negative correlations between viability and fertility, or possibly to the presence of a mutator. The selection for viability and fertility, or possibly to the presence of a mutator. The selection for viability at the average polymorphic locus must be very slight, of the order of 10(-3) or less. PMID- 4218183 TI - Variation of spontaneous occurrence rates of chromosomal aberrations in the second chromosomes of Drosophila melanogaster. AB - After accumulating mutations by the aid of marked inversions, spontaneous occurrence rates of chromosome aberrations were estimated for 1148 chromosome lines that originated from five stem line second chromosomes of Drosophila melanogaster. In chromosome lines originating from three stem chromosomes (CH, PQ, and RT), mutations were accumulated for 7550, 7252, and 7256 chromosome generations, respectively, but no structural change was detected. For the chromosome lines that originated from the other two stem chromosomes, the situation was different: Twenty aberrations (19 paracentric inversions and 1 translocation between the second and the third chromosomes) during 45990 chromosome generations took place in the 500 chromosome lines derived from stem line chromosome (AW), and 92 aberrations (83 paracentric inversions, 6 pericentric inversions, 2 translocations between the second and the third chromosomes and 1 transposition) arose during 45006 chromosome generations in the 500 chromosome lines derived from stem line chromosome (JH). For the AW group the occurrence rate becomes 0.00043 per chromosome per generation for all aberrations and 0.00041 for inversions. For the JH group the corresponding rates are 0.00204 and 0.00198, respectively.-A non-random distribution of the breakpoint on the salivary gland chromosome was observed and the breakpoints were concentrated in the regions 26, 29, 33, and 34.-The cytoplasms and the chromosomes (other than the second chromosomes) were made approximately uniform throughout the experiments. Thus, this remarkable variability in the occurrence rate is most probably due to the differences in one or more chromosomal elements on the original five stem chromosomes. The mutable chromosomes (AW and JH) appear to carry a kind of mutator factor such as hi (Ives 1950). PMID- 4218184 TI - Sideroblastic anaemia and jejunal diverticulosis. PMID- 4218185 TI - Reversibility of atherosclerosis. PMID- 4218186 TI - Partial unilateral lentiginosis with associated developmental abnormalities. PMID- 4218187 TI - The role of radical hysterectomy in adenocarcinoma of the endometrium. PMID- 4218189 TI - Autoradiographic and cytophotometric studies on granulocyte precursors in chronic myeloid leukaemia. PMID- 4218188 TI - Reactive haemolysis test in paroxysmal nocturnal haemoglobinuria. PMID- 4218190 TI - [Platelet factor 3 availability in patients affected by pancreatic diabetes (author's transl)]. PMID- 4218191 TI - [Consumption coagulopathy in association with dissecting aortic aneurysm (author's transl)]. PMID- 4218192 TI - [Chronic idiopathic acquired hypogammaglobulinemia with hypersplenism, sarcoid like arthritis and dermatomyositis. Report of a case (author's transl)]. PMID- 4218193 TI - [The anemia of leukemias and of preleukemic states (author's transl)]. PMID- 4218195 TI - Changes in the neurosecretory apparatus of protein malnurished rats. PMID- 4218194 TI - [Pharmacological study of prostate extracts. (IV). Prostatic acid phosphotases from several different species, and the effect of prostate extracts on these enzyme]. PMID- 4218196 TI - [Disorders in the wound healing after open heart surgery]. PMID- 4218197 TI - [Hiatal hernia and its complications]. PMID- 4218198 TI - [Angiography of the small- and large intestine]. PMID- 4218199 TI - [Homologous insemination. Practical experience with deep-frozen sperma]. PMID- 4218200 TI - [The Half-life of Endogenous Serum Immunoreactive Thyrotropin in Normal Subjects (author's transl)]. PMID- 4218201 TI - [J-chain, a new immunoglobulin subunit]. PMID- 4218203 TI - Effects of radiations on the rate of regeneration in Homalozoon vermiculare (STokes) & Urostyla. PMID- 4218202 TI - [Site and mechanism of the intracranial venous system compression under experimental intracranial hypertension (author's transl)]. PMID- 4218204 TI - 'Diverticulosis' of the fish duodenum infested with cestodes. PMID- 4218205 TI - Pseudomonas aeruginosa in post operative wound infection. PMID- 4218206 TI - Perinatal observations of mother-infant behaviour in the bonnet macaque. PMID- 4218207 TI - Case studies in bioethics. Saying "no" to hemodialysis. Should a minor's decision be respected? PMID- 4218208 TI - A translocation in cattle and its association to polymorphisms in red cell antigens, transferrins and carbonic anhydrases. PMID- 4218209 TI - Cytogenetical localization of the amylase region in Drosophila melanogaster by means of translocations. PMID- 4218210 TI - Position-effect variegation for an isoamylase in Drosophila melanogaster. PMID- 4218211 TI - Puffing pattern of 0-hour prepupae of Drosophila melanogaster. PMID- 4218212 TI - H3-thymidine radioautography of salivary gland chromosomes treated with alkali urea. PMID- 4218213 TI - Whole mount electron microscopy of core fibrils in salivary-gland chromosomes of Drosophila melanogaster. PMID- 4218214 TI - Population studies in northern Sweden. III. Variations of ABO and Rh blood group gene frequencies in time and space. PMID- 4218215 TI - Interchromosomal effects of autosomal inversions in Drosophila melanogaster. PMID- 4218216 TI - The effect of the Curly inversions on meiosis in Drosophila melanogaster. III. Interchromosomal effect of homozygous inversions. PMID- 4218217 TI - Factors influencing the competitive ability of certain wild stocks of Drosophila. PMID- 4218218 TI - The biochemical genetics of rudimentary mutants of Drosophila melanogaster. I. Aspartate carbamoyltransferase levels in complementing and non-complementing strains. PMID- 4218219 TI - Whole mount electron microscopy of small chromomeres in salivary gland chromosomes of Drosophila melanogaster. PMID- 4218220 TI - Whole mount electron microscopy of fibril-rings in alkali-urea treated salivary gland chromosomes of Drosophila melanogaster. PMID- 4218221 TI - Female meiosis and embryonic mitosis in Drosophila melanogaster. I. Meiosis and fertilization. PMID- 4218222 TI - Fitness and fitness components for a two-allele system in Drosophila melanogaster. PMID- 4218223 TI - Exogenous acetylcholinesterase as tracer for extracellular pathways in the brain. PMID- 4218225 TI - Antimetabolites produced by microorganisms. XI. 1-(S)-hydroxy-2-(S,S)-valylamido cyclobutane-1-acetic acid. PMID- 4218224 TI - Histochemical demonstration of the intestinal hetero-beta-galactosidase (glucosidase). PMID- 4218226 TI - Editorial: Diabetes in the young. PMID- 4218227 TI - Completed chromosomes in thymine-requiring Bacillus subtilis spores. AB - Origin:terminus genetic marker ratios (both purA: metB and purA:ilvA) were measured in extracts of spores of Bacillus subtilis strains W23 thy his and 168 thy. For strain W23 thy his, normalized to W23 spore deoxyribonucleic acid, both ratios were equal to unity and were consistent with the presence of only completed chromosomes in the spores. The same ratios in extracts of spores of 168 thy, normalized to strain 168 or the prototroph SB19, were abnormal, i.e., 2.26 +/- 0.10 and 0.71 +/- 0.06 for purA:metB and purA:ilvA, respectively. These values were unaffected by the extent of extraction of the spore deoxyribonucleic acid, the richness of the medium on which they are formed, and the thymine phenotype. The high ratio for purA:metB is in agreement with the results of earlier workers but, because of the low purA:ilvA ratio, cannot be explained simply by the presence of partially replicated chromosomes in spores of strain 168 thy. Furthermore, purA:leuA in such extracts is 1.01 +/- 0.06, consistent with the presence of only completed chromosomes. It is concluded that the abnormal origin:terminus marker ratios are only apparent and result from non isogenicity between strains 168 thy and 168 in the metB thyB ilvA chromosome region introduced during construction of 168 thy by transformation of strain 168 with W23 thy deoxyribonucleic acid. It is concluded further that the chromosomes of strain 168 thy spores are in a completed form. PMID- 4218228 TI - Purification and properties of 3-deoxy-D-arabionheptulosonic acid-7-phosphate synthetase (trp) from Escherichia coli. AB - The 3-deoxy-d-arabinoheptulosonic acid-7-phosphate synthetase which is subject to regulation by tryptophan has been partially purified from a strain of Escherichia coli K-12, in which this is the only functional form of this enzyme activity, and from a similar strain possessing a feedback-resistant form of the enzyme. Maximal observed inhibition by tryptophan of the feedback-sensitive enzyme was 56%. There was no evidence for cooperativity in the saturation of the enzyme with tryptophan or E4P. The molecular weights of the feedback-sensitive and feedback-resistant forms of the enzyme were the same (52,000), and no change was detected in the molecular weight of the feedback-sensitve enzyme in the presence of tryptophan. The effect of tryptophan analogues was tested to determine the nature of the tryptophan binding site. Treatment with ethylenediaminetetraacetic acid removed 80% of the activity of the feedback-sensitive enzyme. This activity was restored upon the addition of Co(2+) or Mn(2+). Neither treatment with ethylenediaminetetraacetic acid nor addition of Co(2+) or Mn(2+) affected the activity of the feedback-resistant enzyme. PMID- 4218230 TI - Activation of inactive nitrogenase by acid-treated component I. AB - When Azotobacter vinelandii was derepressed for nitrogenase synthesis in a N-free medium containing tungstate instead of molybdate, an inactive component I was synthesized. Although this inactive component I could be activated in vivo upon addition of molybdate to the medium, it could not be activated in vitro when molybdate was added to the extracts. Activation occurred, however, when an acid treated component I was added to extracts of cells derepressed in medium containing tungstate. Acid treatment completely abolished component I activity. Mutant strains UW45 and UW10 were unable to fix N(2). Both strains synthesized normal levels of component II but produced inactive component I. Acid-treated component I activated inactive component I in extracts of mutant strain UW45 but not mutant strain UW10. This activating factor could be obtained from N(2)-fixing Klebsiella pneumoniae, Clostridium pasteurianum, and Rhodospirillum rubrum. PMID- 4218229 TI - Lipopolysaccharide containing L-acofriose in the filamentous blue-green alga Anabaena variabilis. AB - For the first time, an O-antigenic lipopolysaccharide (LPS) has been isolated from a filamentous blue-green alga (Anabaena variabilis). It was extractable with phenol-water, resulting in extraction of the bulk of the LPS into the phenol phase. The polysaccharide moiety of this LPS consists of l-rhamnose, its 3-O methyl ether l-acofriose, d-mannose, d-glucose, and d-galactose. l-Glycero-d mannoheptose and 2-keto-3-deoxyoctonate, the two characteristic sugar components of enteric LPS, and phosphate groups are absent from the A. variabilis O antigen. The only amino sugar present is d-glucosamine. Three hydroxy fatty acids were identified, namely, beta-hydroxymyristic, beta-hydroxypalmitic and beta hydroxystearic acids, in addition to palmitic and unidentified fatty acid. The LPS of A. variabilis is localized in the outermost cell wall layer and behaves like a bacterial O antigen in serological tests. The passive hemagglutination yielded high titers with isolated LPS (pretreated by heat or by alkali) and rabbit antisera prepared against living or heat-killed cells. The position of the precipitation arcs after immunoelectrophoresis of the O antigen indicates the lack of charged groups. The water phase of the phenol-water extract contains, in high yield, a glucose polymer. It is serologically inactive as shown by the passive hemagglutination test and by agar-gel precipitation. PMID- 4218231 TI - Glycerolphosphate-containing cell wall polysaccharides from Streptococcus sanguis. AB - Six glycerolphosphate-containing tetraheteroglycans, a, b-1, b-2, b-3, b-4, and b 5, have been purified from the formamide extracts of Streptococcus sanguis by alcohol and acetone precipitations, Sephadex G-75, and diethylaminoethyl cellulose column chromatography. The polysaccharides were judged as at least 95% pure by analytical disc gel electrophoresis and immune double diffusion against rabbit antiserum. They were shown to be cell wall polysaccharides, since they formed a single band of identity in immune double diffusion with partially purified polysaccharide extracted from a purified cell wall preparation of S. sanguis. The polysaccharides were composed of l-rhamnose, d-glucose, and N-acetyl d-glucosamine in a similar molar ratio, but varied in their glycerol and phosphate contents. They exhibited four different mobilities in polyacrylamide disc gel electrophoresis at pH 8.9. When they were treated with formamide at 170 C for 20 min, the faster moving polysaccharide(s) yielded polysaccharides with mobilities corresponding to the other slower moving polysaccharides. These results indicate that the polysaccharides originated from the same cell wall polysaccharide and were produced as a result of breakage in the phosphodiester bonds during the formamide extraction procedure. A preliminary structural study shows that the terminal reducing sugar is l-rhamnose and that the glycerol moiety is probably linked to the polysaccharide through a phosphodiester bond. PMID- 4218234 TI - Properties of thermosensitive extracellular alpha-amylases of Bacillus subtilis. AB - Enzymological properties of four thermosensitive alpha-amylases (M3, M9, M18, and M20) brought by different mutation sites in alpha-amylase structural gene of Bacillus subtilis were compared with those of the parental alpha-amylase NA64. Two thermosensitive alpha-amylases (M9 and M20) were altered not only in their thermosensitivity but also in their immunological properties, catalytic properties, molecular weights determined by the gel filtration on a Bio-Gel P-100 column, and others. The other two thermosensitive alpha-amylases (M3 and M18) were altered only in their thermosensitivity. PMID- 4218232 TI - Characterization of a bacteriophage-induced, host-specific lytic enzyme from lysates of Bacillus stearothermophilus infected with bacteriophage TP-8. AB - Phage TP-8 lysates of Bacillus stearothermophilus 4S or 4S(8) contain lytic activity exhibiting two pH optima, one at pH 6.5 and the other at pH 7.5. Using a variety of fractionation procedures, the two lytic activities could not be separated. At pH 7.5 the lytic enzyme is an endopeptidase which hydrolyzes the l alanyl-d-glutamyl linkage in the peptide subunits of the cell wall peptidoglycan and at pH 6.5 it exhibits N-acetylmuramidase activity. Endopeptidase activity is inhibited by NaCl and neither lytic activity was significantly affected by divalent cations or ethylenediaminetetraacetic acid. Crude lysates contain 2.5 to 3.0 times more endopeptidase activity than N-acetylmuramidase activity. The ratio of the two lytic activities (endopeptidase/N-acetylmuramidase) changes to 1.3 to 1.7 during the course of purification, to 1.0 after isoelectric focusing, and 3.9 and 6.00 after exposure for 2 h at 60 and 65 C, respectively. We conclude that the two lytic activities may be associated with a single protein or a lytic enzyme complex composed of two enzymes. Lytic activity at pH 7.5 is more effective in solubilizing cells or cell walls than the lytic activity at pH 6.5. LiCl extracts of 4S and 4S(8) cells contain lytic activity exhibiting endopeptidase activity at pH 7.5 and N-acetylmuramidase activity at pH 6.5. Lytic activity in these LiCl extracts also has a number of other properties in common with those in lysates of phage TP-8. We proposed that the lytic enzyme(s) are not coded for by the phage genome but are part of the host autolytic system. PMID- 4218233 TI - Thermal death of temperature-sensitive lysyl- and tryptophanyl-transfer ribonucleic acid synthetase mutants of Bacillus subtilis: effect of culture medium and developmental stage. AB - The growth of thermosensitive Bacillus subtilis lysyl- and tryptophanyl-transfer ribonucleic acid synthetase mutants (lysS1 and trypS1) (l-lysine:transfer ribonucleic acid [tRNA] ligase [AMP], EC 6.1.1.6; and l-tryptophan:tRNA ligase [AMP], EC 6.1.1.2) was terminated when exponential phase cells were shifted from 30 to 43 C in a rich medium. Under these conditions, the temperature-inhibited cells undergo thermal death; they rapidly lose their ability to form colonies at 30 C. Another lysyl-tRNA synthetase mutant (lysS2) is refractory to thermal death even though its growth is inhibited at 43 C. The thermal death response of the lysS1 mutant is affected by the stage of cell development. At periods in spore outgrowth and sporogenesis these cells become refractory to thermal death. The refractory state does not result from the production of an inhibitor, or from the degradation of an activator of thermal death. However, culture medium composition does modify the thermal death response. Rich media enhance the effect, and no thermal death occurs in the lysS1 strain grown in a minimal medium. Temperature sensitive cells can grow in a lysine- (0.25 mM) or tryptophan- (0.25 mM) supplemented minimal medium at 43 C, but amino acid concentrations of 25 mM only transiently protect trypS1 and lysS1 cells from thermal death in a rich medium. Osmotic agents such as sucrose (0.5 M) and NaCl (0.34 M) completely prevent thermal death in the lysS1 strain, although growth is still arrested. On solid media, sucrose stabilized lysS1 cells can form colonies at the restrictive temperature, but neither sucrose (0.5 M) nor NaCl (0.34 M) stabilized the lysS1 enzyme in vitro. Chloramiphenicol increased the rate of thermal death of the lysS1 strain but decreased the thermal death response of the trypS1 mutant. Considering the nature of the enzyme defect in the lysS1 strain, the common genetic origin of the spore and vegetative lysyl-tRNA synthetase, and the protective effects exerted by lysine and osmotic agents, it is tentatively concluded that thermal death results from irreversible inactivation of the mutant gene product. According to this hypothesis, either the lysS1 enzyme is altered during sporogenesis or some physiological or structural aspect of this developmental phase can stabilize the mutant phenotype and thereby rescue cells from thermal death. PMID- 4218236 TI - Extracellular enzyme from Myxobacter AL-1 that exhibits both beta-1,4-glucanase and chitosanase activites. AB - An enzyme that has both beta-1,4-glucanase and chitosanase activities is characterized. Evidence for homogeneity was obtained from electrophoresis and sedimentation velocity studies; only one N-terminal amino acid, valine, was found. Results of denaturation studies showed that beta-1,4-glucanase and chitosanase activities decreased at equal rates. With carboxymethylcellulose as the substrate, a K(m) of 1.68 g of carboxymethylcellulose per liter of solution and a V(max) of 2.20 x 10(-9) mol/min were found. With chitosan (the beta-1,4 polymer of glucosamine) as the substrate, a K(m) of 0.30 g of chitosan per liter of solution and a V(max) of 0.75 x 10(-9) mol/min were found. A pH optimum of 5.0 was found for beta-1,4-glucanase activity, and pH optima of 5.0 and 6.8 were found for chitosanase activity. beta-1,4-Glucanase activity had a temperature optimum of 38 C, and chitosanase activity had a temperature optimum of 70 C. Chitosan stabilized both enzyme activities at 70 C. Cellotriose was the smallest polymer capable of hydrolysis. Glucosamine was released by action of the enzyme upon cell wall preparations of several fungi. PMID- 4218235 TI - In vivo kinetics of nitrogenase formation in Clostridium pasteurianum. AB - Clostridium pasteurianum exhibits diauxic growth when grown in the presence of both NH(3) and N(2); no nitrogenase activity or formation was detected either serologically or by activity during growth on NH(3). During the 60-min lag that ensued after NH(3) was consumed and before growth resumed, molybdoferredoxin and azoferredoxin were first detected by activity measurements and serologically at 25 and 40 min, respectively. With the use of rifampin and dactinomycin, it was found that azoferredoxin messenger ribonucleic acid was initiated between 25 and 30 min after the inception of the lag and was completed by 38 min. An explanation of these results and their relation to possible models for the regulation of nitrogenase is given. PMID- 4218237 TI - Pyrolytic biocarbon materials. PMID- 4218240 TI - Scrapie--a personal view. PMID- 4218238 TI - The components of "affectionless psychopathy in institutionalized children. PMID- 4218239 TI - Host-virus relationship with special reference to Newcastle disease and serum hepatitis. PMID- 4218241 TI - Amyotrophic lateral sclerosis, Parkinson's disease, and the amyotrophic lateral sclerosis-Parkinsonism-dementia complex on Guam: a review and summary of attempts to demonstrate infection as the aetiology. PMID- 4218242 TI - Membrane hypothesis of scrapie. PMID- 4218243 TI - The nature of the scrapie agent. PMID- 4218244 TI - Isolation and characterization of the subacute spongiform virus encephalopathies of man: kuru and Creutzfeldt-Jakob disease. PMID- 4218245 TI - Response of whole-body irradiated mice to inoculation of Theileria parva-infected bovine lymphoid cells. PMID- 4218246 TI - Erythrocyte losses from pigs with experimental Trichuris suis infections measured with a whole-body counter. PMID- 4218247 TI - Three cases of suspected mammary neoplasia in non-human primates. PMID- 4218248 TI - The ectopic mandibular second molar. PMID- 4218249 TI - Antibodies to endotoxin from Vibrio cholerae measured by bactericidal and indirect hemagglutination tests. Differences in immunoglobulin classes and specificity. PMID- 4218250 TI - A new method of preparation of specifically purified anti-TNP antibodies. PMID- 4218251 TI - Haemolytic assay of bovine serum complement. PMID- 4218252 TI - Isoelectric focusing of rabbit IgM hemolysin: heterogeneity with respect to charge and function. PMID- 4218253 TI - [Pseudomonas aeruginosa infections]. PMID- 4218254 TI - [Serological diagnosis of Pseudomonas infections, with special reference to diagnosis of respiratory tract infections]. PMID- 4218255 TI - [Interactions between oral streptococci and staphylococci, with special reference to the inhibitory action of Streptococcus viridans on Staphylococcus]. PMID- 4218256 TI - [Serum antibody titers and hemolytic Streptococcus isolated from the throat culture of healthy school children in Okinawa]. PMID- 4218257 TI - [The place of cranio-facial malformations in genetic counseling]. PMID- 4218258 TI - [Ocular phakomatosis. Genetic and therapeutic considerations]. PMID- 4218259 TI - Focal EEG in post-traumatic mild coma. Follow-up study on unoperated patients. PMID- 4218260 TI - Polychlorobiphenyl toxicity and nutrition. II. PCB toxicity and vitamin A (2). PMID- 4218261 TI - [Observation on experimental serous otitis media]. PMID- 4218262 TI - Proceedings: The release of thyrotrophin in response to thyrotrophin releasing hormone (TRH) in the pregnant ewe, lamb foetus and neonatal lamb. PMID- 4218263 TI - Proceedings: Dorsal horn neurons excited by cutaneous cold receptors in primates. PMID- 4218264 TI - Cancers of the larynx and hypopharynx. II. Laryngeal cartilage behaviour. PMID- 4218265 TI - [Multiple diverticula of the ureter (author's transl)]. PMID- 4218266 TI - [Intraluminal diverticulum of the duodenum]. PMID- 4218267 TI - The relationship between listericidal and mycobacteriostatic activity in BCG vaccinated mice. PMID- 4218268 TI - Treatment of juvenile rheumatoid arthritis -- a world survey. PMID- 4218269 TI - [Neurologic vesico-sphincteric dysfunctions. Urinary complications of neurologic vesico-sphincteric dysfunctions]. PMID- 4218270 TI - [Fundamental and clinical studies of amikacin (BB-K8) in surgical field (author's transl)]? PMID- 4218272 TI - [Clinical evaluation of lividomycin (LVDM) on acute gonorrhea (author's transl)]. PMID- 4218271 TI - [Microbiological studies on the combination effect of rifampicin and nalidixic acid (author's transl)]. PMID- 4218273 TI - [Morphological study of HB antigen with special emphasis on electron microscopic study of liver cells of HB antigen carriers]. PMID- 4218274 TI - [Clinico-pathological study of asymptomatic carriers of HB antigen]. PMID- 4218275 TI - [HB antigen as a possible factor for causing liver neoplasm--an immunological viewpoint]. PMID- 4218276 TI - [Properties of LDH-binding immunoglobulin - detection of anti-LDH monoclonal autoantibody]. PMID- 4218277 TI - [Prospect of tuberculosis research. In reference to bacteriological aspect (author's transl)]. PMID- 4218278 TI - [Prospect of tuberculosis research. In reference to chemistry (author's transl)]. PMID- 4218279 TI - [Chemotherapy of tuberculosis]. PMID- 4218280 TI - [Mycobacterium tuberculosis and acid-fast bacteria]. PMID- 4218281 TI - [Absences after mumps meningitis]. PMID- 4218282 TI - [The course of myoclonic-astatic petit mal]. PMID- 4218283 TI - Studies on the live attenuated rubella virus vaccine. II. Research concerning attenuation of "Takahashi strain" isolated in Japan. PMID- 4218284 TI - [Use of amino acid complex in surgical diseases of the organs of the abdominal cavity]. PMID- 4218286 TI - Interaction between glucocorticoids and TSH secretion. PMID- 4218285 TI - Immune response in patients with autoimmune thrombocytopenia and autoimmune haemolytic anaemia receiving azathioprine. PMID- 4218288 TI - [Editorial: Prohibition of intravenous feeding]. PMID- 4218287 TI - Clinical observations on therapeutic applications of thyrotropin-releasing hormone (TRH). PMID- 4218289 TI - [Typhoid and paratyphoid fever in Swedish travellers abroad--why do we vaccinate]. PMID- 4218290 TI - [4 million seek increased use of protons for cancer therapy]. PMID- 4218291 TI - [Meningococcal disease]. PMID- 4218292 TI - Two minutes with diabetes. PMID- 4218293 TI - Effect of eight tetracyclines on growth and lipase formation of Staphylococcus aureus. PMID- 4218295 TI - Influence of growth conditions on the formic: acetic acid ratio in Escherichia coli and Streptococcus faecalis. PMID- 4218294 TI - Surface properties of cells of gentamicin-sensitive and gentamicin-resistant strains of Pseudomonas aeruginosa. PMID- 4218296 TI - The anti-proteins in Salmonella monofactor sera. PMID- 4218297 TI - Immunity to influenza in ferrets. IX. Delayed hypersensitivity following infection or immunization with A2/Hong Kong virus. PMID- 4218298 TI - [Fractionization of immunglobulins in the serum of patients suffering from liver diseases by means of simple radial immundiffusion (Partigen-test) (author's transl)]. PMID- 4218299 TI - [Blepharo-oculo-cranial dysplasia-a so far unknown syndrome? (AUTHOR'S TRANSL)]. PMID- 4218300 TI - [Immunochemical characteristics of antigens isolated from larval stages of Taeniarhynchus saginatus]. PMID- 4218302 TI - [Study of a non deleted bobbed mutant (author's transl)]. PMID- 4218301 TI - Functional diversity within the rudimentary locus of Drosophila melanogaster. AB - The rudimentary locus of Drosophila melanogaster is shown to be at least bifunctional. Mutants in different regions of the locus have either no CPSase or no ATCase activity; some mutants lack both activities. The results are discussed in correlation with the complementation and genetic map of the locus. PMID- 4218303 TI - A meiotic effect of a mutator gene in Drosophila melanogaster. PMID- 4218304 TI - Vulture retina enzyme distribution and function. PMID- 4218305 TI - On the cleavage of starch and disaccharides in the human oral cavity. PMID- 4218306 TI - New aspects of malnutrition in Jakarta. PMID- 4218307 TI - A case of paratyphoid fever accidentally treated with amoxycillin. (Case report). PMID- 4218309 TI - [Parenteral feeding in premature and newborn infants]. PMID- 4218308 TI - [Exomphalos-macroglossia-gigantism syndrome(author's transl)]. PMID- 4218310 TI - [Gaint omphalocele: provisonal covering with silastic, and parenteral feeding during 6 months]. PMID- 4218311 TI - [Mucolipidosis Type II. STudy of 2 familial cases. Clinical and biochemical aspects]. PMID- 4218312 TI - Autonomic and behavioral temperature regulation. Unilateral vs bilateral preoptic thermal stimulation. PMID- 4218313 TI - [Myoclonic encephalopathies induced by bismuth salts. 6 cases observed during long-term oral treatment]. PMID- 4218314 TI - [The new meningococcal vaccines]. PMID- 4218315 TI - Ryle's tube. John Ryle (1889-1950). PMID- 4218316 TI - Repeat prescription cards. PMID- 4218317 TI - [Liver function and anaesthesia with ethrane and halothane in rats (author's transl)]. PMID- 4218319 TI - [Prophylaxis and therapeutic management of acute renal failure in surgical patients (author's transl)]. PMID- 4218318 TI - [Infusion therapy in paediatric surgery (author's transl)]. PMID- 4218320 TI - [Quantitative and qualitative studies of urinary proteins in healthy children (author's transl)]. PMID- 4218321 TI - [Absorptive activity of macrophages and polynuclear cells with regard to Mycobacteria in pulmonary tuberculosis]. PMID- 4218322 TI - [Significance of certain lipids of Mycobacterium tuberculosis (literature review)]. PMID- 4218323 TI - [Serological and biochemical indentification of atypical Mycobacteria]. PMID- 4218324 TI - [Method of determination of niacin with the aid of paper strips]. PMID- 4218325 TI - [Effect of pyrazinamide on pH of cytoplasm sections surrounding phagocytized Mycobacteria]. PMID- 4218326 TI - [Characteristics of patients, carriers of Mycobacterium tuberculosis, according to materials of a tuberculosis hospital]. PMID- 4218327 TI - [Characteristics of the course of meningeal tuberculosis with the presence of L forms of Mycobacterium tuberculosis in the cerebrospinal fluid]. PMID- 4218328 TI - [Comparative bacteriological examinations of sputum and resected material from patients with pulmonary tuberculosis]. PMID- 4218330 TI - Proceedings: Linolenic acid deprivation in Capuchin monkeys. PMID- 4218329 TI - The use of intestinal markers to measure digestive function in ruminants. PMID- 4218331 TI - Proceedings: Lipid composition of human milk: comparative studies on African and European mothers. PMID- 4218332 TI - Immunodepressive effects of combination chemotherapy with N-diazoacetylglycine amide, L-asparaginase, and cortisone, in mice. PMID- 4218333 TI - Central nervous system toxic manifestations of sodium cyanate. PMID- 4218334 TI - [A simple method for the determination of platelet aggregation in clinical medicine using exogenous]. PMID- 4218335 TI - Glycogen in the central nervous system. PMID- 4218336 TI - Radial immunoassay of erythrocyte carbonic anhydrase enzymes: a screening procedure to detect megaloblastic erythropoiesis. PMID- 4218337 TI - Reversal by Pseudomonas aeruginosa of rifamycin SV inhibition of Staphylococcus aureus in vitro and in vivo. PMID- 4218338 TI - [Intestinal absorption in marasmic infants]. PMID- 4218339 TI - [Clinico-radiological evaluation of duodenal diverticulosis]. PMID- 4218340 TI - [Causes and prognosis of convulsive epileptic status. An analysis of 40 consecutive cases]. PMID- 4218341 TI - [Hyperosmolar hyperglycemic nonketoacidotic coma]. PMID- 4218342 TI - [Comparative studies on the composition of 15 phenotypes of Drosophila melanogaster Mg (adults and larvas) (author's transl)]. PMID- 4218343 TI - Letter: Enhancement of E-rosettes formation after treatment of lymphocytes with papain. PMID- 4218345 TI - [Identification and importance of the 7S subunity in Waldenstrom's macroglobulinemia (author's transl)]. PMID- 4218344 TI - Increased phosphorylation of nuclear phosphoproteins in precancerous liver. PMID- 4218346 TI - [Survey of Neisseria meningitides carriers in Mexico City. Preliminary report]. PMID- 4218347 TI - Role of some elements on the enzymatic transformation of cortisol with Bacillus cereus. PMID- 4218348 TI - [Counter-immunoelectrophoresis applied to the serological classification of Streptococcus beta hemolyticus]. PMID- 4218349 TI - [Study of Bacillus megaterium isolated from "tesguino" (an alcoholic beverage) of Chihuahua, Mexico]. PMID- 4218350 TI - [Studies of various aspects of schistosomiasis mansoni in Cebus monkeys using the quantitative oogram method]. PMID- 4218351 TI - [Studies on wild reservoirs and vectors of Trypanosoma cruzi. LV. Natural infection of the rat Holochilus braziliensis leucogaster (Brandt, 1835 by T. cruzi)]. PMID- 4218352 TI - [Experimental therapy of schistosomiasis mansoni. IX. Observations on the activity of quinine and its isomers]. PMID- 4218353 TI - [Study of hemagglutinating antigens in the serodiagnosis of Chagas' disease]. PMID- 4218355 TI - [Clinico-statistical evaluation of the Rh problem in the Clinica Ostetrica e Ginecologica of the University of Siena in the years 1970,1971 and 1972]. PMID- 4218354 TI - Experimental chemotherapy of schistosomiasis. VII. Laboratory and clinical trials with sodium antimony dimethylcysteine tartrate (NaP). PMID- 4218356 TI - Experimental bases of chronic lung diseases. PMID- 4218357 TI - [Ecological aspects of South American trypanosomiasis. VI. Persistence Triatoma sordida after environmental alterations and its possible relation to the dispersion of the species]. PMID- 4218358 TI - Cold induced retraction of reptilase clots. PMID- 4218359 TI - Platelet factor 4 (PF-4). An electroimmuno assay for PF-4 in human plasma. PMID- 4218360 TI - Human secretory component. II. Physicochemical characterization of free secretory component purified from colostrum. PMID- 4218361 TI - IgM reassociation in Vitro: no influence of J chain on the amount of polymers. PMID- 4218363 TI - Comparative study of antibody-dependent and direct lymphocyte-mediated cytotoxicity in vitro after alloimmunization in the human. II. Chemical inhibitors. PMID- 4218362 TI - Antibody-dependent cell-mediated cytotoxicity in the mouse. I. Surface characteristics of an effecter cell. PMID- 4218364 TI - N-terminal amino acid sequence of amyloid fibril protein AR, prototype of a new lambda-variable subgroup, V lambda V. PMID- 4218366 TI - A monoclonal IgG protein with antibody-like activity for transferrin and with kappa chains of an unusual molecular size. PMID- 4218365 TI - Surface IgD in immunoproliferative disorders. PMID- 4218367 TI - Comparison of Fch and Fc fragments of IgG3: evidence of an intra-chain S-S bridge in the hinge of gamma3 chains. PMID- 4218368 TI - The tuberculosis morbidity among pathologists in Finland. PMID- 4218369 TI - Pathophysiology of Cholelithiasis. PMID- 4218370 TI - [Familial incidence of bronchiectasis and alpha-1 antitrypsin deficiency]. PMID- 4218371 TI - [Prognosis of currently available methods of gonorrhea detection]. PMID- 4218372 TI - [Treatment of acute respiratory insufficiency in surgical patients]. PMID- 4218373 TI - The relationship between protein-calorie malnutrition and trichinosis: 1. Studies on the number of intestinal worms and muscular larvae in rats fed low and high protein diets. PMID- 4218374 TI - [Pharmacologic hypotonia and double contrast x-ray diagnosis of the resected stomach]. PMID- 4218375 TI - Cardiac malformations and other effects due to insecticides in embryos of the killifish, Fundulus heteroclitus. PMID- 4218376 TI - The effects of moderate hypoxia and moderate hypoxia plus hypercapnea on cardiac development in chick embryos. PMID- 4218377 TI - Properties of soluble fibrin polymers encountered in thrombotic states. PMID- 4218378 TI - [Evaluation of the rapid B. subtilis BGA test (author's transl)]. PMID- 4218379 TI - Inactivation mechanism of tyrosinase. PMID- 4218380 TI - B lymphocytes bearing immunoglobulins in multiple sclerosis. PMID- 4218381 TI - Cross-neutralization by tiger snake (Notechis scutatus) antivenene and sea snake (Enhydrina schistosa) antivenene against several sea snake venoms. PMID- 4218382 TI - Studies on Egyptian Cerastes cerastes antivenin. PMID- 4218383 TI - [Antibacterial effect of the tissue adhesive Fimomed]. PMID- 4218384 TI - The mesosome--a clue to the evolution of the plasma membrane. PMID- 4218385 TI - Susceptibility of a new world monkey (Aotus trivirgatus) to an old world simian malarial parasite (Plasmodium knowlesi). PMID- 4218386 TI - Rickettsioses in Australia: isolation of Rickettsia tsutsugamushi and R. australis from naturally infected arthropods. PMID- 4218387 TI - Letter: A skin test for the diagnosis of Chagas's disease. PMID- 4218388 TI - Letter: Serology of human sacosporidiosis. PMID- 4218390 TI - Diabetes in Kenya. PMID- 4218389 TI - Orthopaedic tuberculosis in the tropics. PMID- 4218391 TI - Serum immunoglobulin patterns in South African population groups. PMID- 4218392 TI - Folate levels in protein malnourished Nigerian children. PMID- 4218393 TI - [Clinical study of malnutrition in a southern Tunisian region]. PMID- 4218394 TI - [Littre's hernia (strandulation of Meckel's diverticulum in an inguinal hernia)]. PMID- 4218395 TI - [Tuberculous arthritis: apropos of a case and review of current concepts concerning its pathogenesis]. PMID- 4218396 TI - [Neurofibromatosis: renovascular hypertension, stenosis of the abdominal aorta, the hepatic artery and the superior mesenteric artery]. PMID- 4218397 TI - Human immunity to gonococci: studies of opsonization by sera of prostitutes and nuns. PMID- 4218398 TI - [Rare anamaly of the extrahepatic biliary tract]. PMID- 4218399 TI - [Selection of a method of surgery for duodenal ulcers complicated by obstructive jaundice]. PMID- 4218400 TI - [Fat emulsion lipomaise in the complex parenteral feeding of patients]. PMID- 4218401 TI - [Current problems of acute intestinal obstruction]. PMID- 4218403 TI - [Carnivores as the source of swine sarcocyst infestation]. PMID- 4218402 TI - [Effect of vitamin C and antibiotics on immunogenesis]. PMID- 4218404 TI - A cytophotometric study of the DNA distribution in Ehrlich ascites tumour populations at different stages of development. PMID- 4218405 TI - Cytogenetic studies of ectopic pregnancies. PMID- 4218406 TI - [The cell composition of the red pulp of mice. I. Autoradiographic investigations with 3H-thymidine in thin sections (author's transl)]. PMID- 4218407 TI - [The cell composition of the red pulp of mice. II. Electronmicroscopic and autoradiographic investigations on megakaryocytes (author's transl)]. PMID- 4218408 TI - Influence of X-irradiation on the different stages of the cell cycle in regenerating rat liver. PMID- 4218409 TI - The diagnostic value of the DNA content of fine needle biopsies of the thyroid gland. PMID- 4218411 TI - Cultivation and survival studies of Neisseria gonorrhoeae in a human diploid cell strain. AB - Neisseria gonorrhoeae was cultivated in a human diploid cell strain (WI-38). Eighty percent of the cultures contained viable gonococci for at least 4 m at 36 degrees C, as evidenced by subculture to brain heart infusion broth. Monthly subcultures of bacteria could be made to fresh WI-38 cultures for at least 11 monthly passages with a 69% survival rate. The identity of gonococci was confirmed by morphology, gram staining, oxidase testing and fermentation reactions. Viability in brain heart infusion broth, minimum essential medium (Eagle), and WI-38 spent fluid was of much shorter duration. The organisms grown in WI-38 cultures appeared to orient largely in the vicinity of the WI-38 cells as well as within the cytoplasm of the cells. PMID- 4218410 TI - [Luminescence microscopy of Koch's bacillus in the diagnosis of pulmonary tuberculosis]. PMID- 4218413 TI - [Effectivity of anticoagulation and extension of long-term anticoagulant therapy]. PMID- 4218412 TI - [Effect of tox enzymes on phagocytosis ability, ciliary movement and metabolism of Tetrahymena pyriformis]. PMID- 4218414 TI - [Importance and necessity of infusion-urographic examinations in the treatment of bladder carcinoma]. PMID- 4218415 TI - [Cold-sterilization of breathing circuits with ultrasonic aerosols of peracetic acid (author's transl)]. PMID- 4218416 TI - [Quantitative 2-dimensional immunoelectrophoresis]. PMID- 4218417 TI - [Effects of coronary vaso dilators on myocardial survival time in the rat under anoxia conditions]. PMID- 4218418 TI - [Studies on the course of mass screening in discovered diabetic patients]. PMID- 4218419 TI - [IgD in the serum of pregnant women]. PMID- 4218420 TI - [The bacterial content of various hospital departments (author's transl)]. PMID- 4218421 TI - Bacterial density in operation wounds. PMID- 4218422 TI - Antisepsis of the operation site with aqueous cetrimide/chlorhexidine and chlorhexidine in alcohol. PMID- 4218423 TI - Aseptic barriers of plastic to prevent bacterial contamination of operation wounds. PMID- 4218425 TI - Absorption of vitamin B12 in rats with jejuno-ileal transposition. PMID- 4218424 TI - Experimental extracorporeal liver perfusion in vivo with daunomycin and 5-fluoro uracil. PMID- 4218426 TI - Duodenal diverticulum with intermittent biliary stasis. PMID- 4218427 TI - [So-called "adenomyomas of the gallbladder base". Apropos of 256 operated personal cases]. PMID- 4218428 TI - [Investigation of alpha-fetoproteins in pregnant women and newborns]. PMID- 4218429 TI - Poly(A)-containing RNA molecules in electrophoretically separated fractions of rapidly labeled nuclear RNA from unstimulated and PHA-stimulated human lymphocytes. PMID- 4218431 TI - Origin, morphologic and functional characteristics of a new lymphoid cell type in irradiated mouse bone marrow. PMID- 4218430 TI - Site of action of desferrioxamine in removing iron in normal and pathological conditions. PMID- 4218432 TI - The gamma-chain in a Ghanaian adult, homozygous for hereditary persistence of fetal haemoglobin. PMID- 4218433 TI - Homozygous beta delta-thalassaemia. Description of a case and review of the literature. PMID- 4218434 TI - Methods for measurement of the cerebral blood flow. PMID- 4218435 TI - Some properties of proteolytic enzymes in human saliva. PMID- 4218436 TI - A histochemical and electron microscopical study of so-called intravenous fat pigment. PMID- 4218437 TI - Three autopsy cases of so-called neonatal necrotizing enterocolitis. PMID- 4218438 TI - Gas chromatography of bacterial whole cell methanolysates; IV. A procedure for fractionation and identification of fatty acids and monosaccharides of cellular structures. PMID- 4218439 TI - Gas chromatography of bacterial whole cell methanolysates; V. Fatty acid composition of Neisseriae and Moraxellae. PMID- 4218440 TI - Protein A production in different strains of Staphylococcus aureus under varied growth conditions. PMID- 4218441 TI - Activities of some enzymes concerning pyruvate metabolism in Neisseria. PMID- 4218442 TI - Immunological comparison of NADP-dependent glutamate dehydrogenase and malate dehydrogenase in genus Neisseria. PMID- 4218443 TI - Purine metabolism in Neisseria meningitidis. 2. Utilization of exogenous adenosine, guanosine and inosine. PMID- 4218444 TI - Acetylsalicylic acid intolerance. PMID- 4218445 TI - Epilepsy in the elderly. AB - Among 50 geriatric inpatients (average age 79) with late-onset epilepsy (average duration two years), 28 had grand mal attacks, 12 had focal attacks, seven had both. None had petit mal, confirming its rarity in the elderly. The epilepsy followed cerebrovascular disease (usually with hemiplegia) in 21 patients (8 per cent of all our patients with hemiplegia in the two-year study period developed epilepsy). Associated conditions included dementia in seven; and cerebral tumours (usually metastases) in five. This latter group survived less than two months on average from the onset of their attacks. The majority of patients (42 out of 50) were unfit for full neurological investigation; and the dangers of some procedures in the elderly are stressed. PMID- 4218446 TI - Research in Coccidia and other Apicomplexa. A progress report. PMID- 4218449 TI - Letter: Hyperalimentation procedures. PMID- 4218447 TI - [Specific hyposensitization using pyridine extracts precipitated with aluminum. III. Intolerance to the extracts. Anatomo-pathological study of the receptor area]. PMID- 4218448 TI - Disodium cromoglycate in the treatment of bronchial asthma. Study of 479 cases during ten months. PMID- 4218450 TI - Current drug therapy--antiepilepsy agents. PMID- 4218451 TI - The adult respiratory distress syndrome. PMID- 4218454 TI - [Treatment of resections of the small intestine after the immediate post operative period]. PMID- 4218452 TI - [Plasma substitutes and blood group serology. Part 1: experimental studies on the influence of different plasma substitutes on the blood group determination (author's transl)]. PMID- 4218455 TI - [Therapeutic, metabolic and electrolytic prevention of post-stress digestive disorders. The anesthesiologist faced with post-stress disorders of intestinal transit]. PMID- 4218456 TI - [Luteotrophic factors in the ewe]. PMID- 4218457 TI - [Aptitude of lactic streptococcus for proteolysis. II. The action of proteolytic system of Streptococcus lactis on whole casein]. PMID- 4218458 TI - [Cranio-carpo-tarsal dysplasia or the whistling face syndrome (author's transl)]. PMID- 4218459 TI - Membrane-peptidoglycan association in the in vitro biosynthesis of the peptidoglycan of Micrococcus luteus. PMID- 4218460 TI - Phenotypic expression of an envC-division mutant of Escherichia coli K12. PMID- 4218461 TI - A change in cell diameter associated with an outer membrane lesion in a temperature-sensitive cell division mutant of Salmonella typhi-murium. PMID- 4218462 TI - The role of divalent cations in the rigid layer of morphological and conditional mutant of Klebsiella pneumoniae Mir M7. PMID- 4218463 TI - [Phospholipid metabolism in asporogenous mutants of "Bacillus subtilis" during exponential growth (author's transl)]. PMID- 4218464 TI - [Migrating foreign bodies in the common bile duct. General review apropos of 3 cases]. PMID- 4218465 TI - Functional disorders of the oesophagus. Roentgenological, cineradiographic and manometric study. PMID- 4218466 TI - ["In vivo" suppression of immunoglobulin synthesis in mice by treatment with anti mu chain antibodies: the effect on IgG1, IgG2 and IgM levels]. PMID- 4218467 TI - [Purification of a specific antigen from hydatid fluid (author's transl)]. PMID- 4218468 TI - Behavioral responses to insect pheromones. PMID- 4218469 TI - Insect nutrition: current developments and metabolic implications. PMID- 4218470 TI - Neuro-hormonal control of sexual behavior in insects. PMID- 4218471 TI - [Effect of pyrogenal on blood lysozyme activity in rabbits]. PMID- 4218472 TI - [Penicillin pharacokinetics under repeated administration]. PMID- 4218473 TI - [Comparative study of the chemotherapeutic action of semisynthetic penicillins in a generalized staph infection in mice]. PMID- 4218474 TI - Propylene oxide as sterilizing agent. AB - Liquid propylene oxide added to a variety of disinfectant solutions resulted in a significant reduction of the bacterial spore content of these solutions. PMID- 4218475 TI - [Detection of Pseudomonas aeruginosa in water]. PMID- 4218476 TI - Influence of insecticide exposure on the in vivo and in vitro metabolic activity of rats. PMID- 4218477 TI - [Treatment of saturnism with a low dose of calcium disodium EDTA]. PMID- 4218478 TI - [Experimental studies on acutely increased intractanial pressure, especially on: I) shift of paramedian artery in the brain stem, II) macrocirculation hemorrhage in the brain stem, III) vasopressor response (author's transl)]. PMID- 4218479 TI - Gold therapy in rheumatoid arthritis. PMID- 4218480 TI - [Non-surgical treatment of postoperative fistulas of the proximal portion of the digestive tract using parenteral hyperalimentation]. PMID- 4218481 TI - [Detection of viral antigens in feline leukemia by immunofluorescence. A model for the study of human leukemia]. PMID- 4218482 TI - Is Sarcocystis tenella two species. PMID- 4218483 TI - Alcohol dehydrogenase in Drosophila melanogaster: activity variation in natural populations. PMID- 4218484 TI - Immunological relationships and post-translational modification of human salivary amylase (Amy) and pancreatic amylase (Amy) isozymes. PMID- 4218485 TI - A method for determining diamine oxidase (histaminase) in biological fluids. PMID- 4218486 TI - A method for assaying hepatic morphine UDP-glucuronyl transferase. PMID- 4218487 TI - [Longitudinal evaluation of the radioimmunological (RIA) determination of HB Ag in viral hepatitis]. PMID- 4218488 TI - [Diphosphonate (disodium etidronate) lowers cholesterol and total lipid levels in the blood of humans]. PMID- 4218489 TI - [Bacteriological studies of the bacterial flora of acute dental infections]. PMID- 4218490 TI - [Changes in urinary acid oligosaccharides after transfusion of normal plasma in 2 cases of Sanfilippo's syndrome]. PMID- 4218491 TI - [Effect of the combination of raubasine and hydrogenated ergot alkaloids on the isolated and perfused rat caudal artery and rabbit internal carotid artery]. PMID- 4218493 TI - Present status of treatment of the mucopolysaccharidoses. PMID- 4218492 TI - Cross pathway regulation of tyrosine and histidine synthesis in Bacillus subtilis. Biochemical, genetic, and transfer RNA studies. PMID- 4218494 TI - Clinical heterogeneity in mucopolysaccharidosis. II. Evidence for epistasis. PMID- 4218495 TI - Stickler syndrome. Presenting as a syndrome of cleft palate, myopia and blindness inherited as a dominant trait. PMID- 4218496 TI - Case report. Case 2 (mucolipidosis III). PMID- 4218498 TI - [Transfer of polychloro biphenyl to food from packaging materials]. PMID- 4218497 TI - [New concepts in the classification of malignant hemopathies]. PMID- 4218499 TI - Arousal effects on unit responsiveness to vocalizations in squirrel monkey auditory cortex. PMID- 4218500 TI - Behavior in Drosophila melanogaster. A geneticist's view. PMID- 4218501 TI - Cytoplasmic membrane changes in conjugating Tetrahymena. PMID- 4218502 TI - Retinal projections traced with thaw-mount autoradiography and multiple injections of tritiated precursor or precursor cocktail. PMID- 4218503 TI - Fluorescence-activated cell sorting of human T and B lymphocytes. I. Direct evidence that lymphocytes with a high density of membrane-bound immunoglobulin are precursors of plasmacytes. PMID- 4218504 TI - Macrophage migration from an agarose droplet: a micromethod for assay of delayed hypersensitivity in the mouse. PMID- 4218505 TI - [Analytical studies on ergot alkaloids and their derivatives. II. New systems for separation of hydrogenated ergot alkaloids by means of thin-layer chromatography]. PMID- 4218506 TI - Serological testing in malaria. AB - The main purpose of this paper is to evaluate, in a critical manner, various serological tests with general emphasis on their value in the epidemiological assessment of malaria. Several tests have been employed in the past. However, the present memorandum will deal only with the methods that have been widely used recently-i.e., indirect immunofluorescence (IFA), passive haemagglutination (IHA), and gel-diffusion. The three immunoglobulins most commonly involved in these tests are IgG, IgM, and-to a lesser extent-IgA. PMID- 4218507 TI - [Immunity against cancer. Use of spontaneous tumors of domestic animals as models for research: 2]. PMID- 4218508 TI - [New data concerning chromosomes of the American planaria Procotyla fluviatilis Leidy]. PMID- 4218509 TI - [Ultrastructure of: Sarcocystis tenella cyst architecture and aspect of endozoites in scanning electron microscopy]. PMID- 4218510 TI - [Determination, by tritiated thymidine incorporation, of the stages of cellular cycle in the axolotl germ in synchronous period of segmentation]. PMID- 4218511 TI - [Suppression of the post-hemorrhagic hyperlipemia and maintenance of erythropoietic stimulation in rabbits previously hypophysectomized]. PMID- 4218512 TI - [Testosterone production by embryonic testis of mouse in organ culture]. PMID- 4218513 TI - [Purification of Pyrocystis lunula luciferase]. PMID- 4218514 TI - [Identification of 4-deoxy-D-threohexulose (4-deoxy-D-fructose) in human urine]. PMID- 4218515 TI - [Primary structure of the bovine erythrocyte carbonic anhydrase CI]. PMID- 4218516 TI - [Localization of the antigen common to the thymus gland and brain in the rat]. PMID- 4218518 TI - [Autofluorescence and presence of biogenic amines in the central nervous system of Crepidula fornicata (Phil.) Mollusca Gasteropod Prosobranch]. PMID- 4218517 TI - [Quantitative cytochemical study of total proteins in Ehrlich tumor cells]. PMID- 4218519 TI - [Ultrastructure of the spermatozoa of Glossiphonia complanata L. (Hirudinee, Rhynchobdelle)]. PMID- 4218520 TI - [Cytochemical localization and quantitative determination of peroxidase activity of human thyroid]. PMID- 4218521 TI - [Viral infection in rickettsia of the scorpion Buthus occitanus Amoreux]. PMID- 4218522 TI - [Comparative metabolic activity of the microflora of lamb and adult sheep rumen: in vitro use of urea nitrogen and carbohydrates]. PMID- 4218523 TI - [Elimination of recessive genes with visible effects in bovine populations where bulls are tested by their descendants]. PMID- 4218524 TI - [Geophagia and mineral nutrition in wild primates]. PMID- 4218525 TI - [In vitro biosynthesis of the macromolecules of gastric mucosa]. PMID- 4218526 TI - [Study of the products of pepsin digestion of dimeric forms of human serum IgA]. PMID- 4218527 TI - [Raman resonance diffusion of chlorophyll d]. PMID- 4218528 TI - [Demonstration in the hypothalamus and partial purification of a substance which inhibits in vitro cell multiplication]. PMID- 4218529 TI - [Paradoxal resistance of athymic mice to infection by Listeria monocytogenes and Salmonella typhimurium and immunostrimulating effect of phospholipid bacterial extract (epg)]. PMID- 4218530 TI - [Inhibiting effect of 5 n-amyl=recorcinol on lymphoblastic transformation]. PMID- 4218531 TI - [Fate of soluble starch after intravenous injection in the rat]. PMID- 4218533 TI - [Separation and reassociation of gonadotropin subunits of a teleostean fish, the carp (Cyprinus carpio L.)]. PMID- 4218532 TI - [In vivo stability of plutonium (239-Pu) in citrate form. Study of its elimination and its hepatic fixation in the rat]. PMID- 4218534 TI - [Toxicity of phenylmercury hydroxide on the fresh water algae Scenedesmus subspicatus W. and W. and Euglena gracilis Klebs]. PMID- 4218535 TI - [Vaccine properties of Brucella fractions]. PMID- 4218536 TI - [Excitation of the neurons of the preopticoseptal region by iontophoretic application of acetylcholine]. PMID- 4218537 TI - [Estimation of the phylogenetic distance between prokaryotic species through the use of ribosomal proteins]. PMID- 4218538 TI - [C-terminal sequence of a parvalbumin from rabbit muscle]. PMID- 4218539 TI - [3H-estradiol-macromolecular complexes in the cell nucleus of guinea-pig fetus kidney. Direct binding of estradiol to the chromatin fraction]. PMID- 4218540 TI - [Acid and enzyme hydrolysis of the thymine fragment modified and bound to the polynucleotide chain after in vitro gamma irradiation of DNA of E. coli]. PMID- 4218541 TI - [Quantitative study of changes of the shape of erythrocytes produced by cationic and anionic derivatives of phenothiazine]. PMID- 4218542 TI - [Isolation of 2 SL-A histocompatibility antigens of swine and biochemical characters]. PMID- 4218543 TI - Distribution of plasma proteins and hyaluronic acid in synovial fluid and serum of human subjects in hydarthrosis. PMID- 4218544 TI - Comparison of serum vitamin B12 determination by two isotope dilution methods and by Euglena assay, with special reference to low values. PMID- 4218545 TI - The use of merthiolate for TBG-blocking in the radioimmunoassay of triiodothyronine. PMID- 4218547 TI - Letter: Comments on the article, "Chlorinated hydrocarbons in the Sargasso Sea atmosphere and surface water. PMID- 4218546 TI - Effect of depletion of serum calcium by EGTA on canine pancreatic secretion induced by dopamine and by secretin. PMID- 4218548 TI - [Rh-immunization following abortion]. PMID- 4218549 TI - Relation between pituitary responsiveness to thyrotropin releasing hormone and serum thyroid hormones in hyperthyroidism. PMID- 4218551 TI - [Symposium: Monkeys as human models. 2. Their effectiveness and limitations as experimental models in toxicology studies]. PMID- 4218550 TI - In vitro inhibition of succinic dehydrogenase by manganese and its reversal by chelating agents. PMID- 4218552 TI - [Symposium: Monkeys as human models. 3. Viral infections]. PMID- 4218553 TI - [Symposium: Monkeys as human models. 4. Dentistry]. PMID- 4218554 TI - [Symposium: Monkeys as human models. 6. Nutrition and growth]. PMID- 4218557 TI - [Symposium: Protection and utilization of wild monkeys]. PMID- 4218556 TI - [Symposium: Monkeys as human models. 8. Psychological and behavioral studies]. PMID- 4218555 TI - Symposium: Monkeys as human models. 7. Neurophysiological studies. PMID- 4218558 TI - [Symposium: Concepts of the "normal data" and "naturally occuring diseases" in monkeys]. PMID- 4218559 TI - [Symposium: Protection in the natural environment, care and breeding of monkeys. 3. Problems of their adaptation to the laboratory environment and thermal metabolic reactions]. PMID- 4218560 TI - [Symposium: Necessity and methodology of breeding monkeys for laboratory use]. PMID- 4218561 TI - [Symposium: Experimental projects using monkeys--some considerations in procurement and utilization of the animals]. PMID- 4218562 TI - Test for mycoplasma on tissue culture vaccines. PMID- 4218563 TI - Experiences in the use of biological indicators in ethylene oxide sterilization. PMID- 4218564 TI - Microbacterium lacticum, troublemaker in blood fractions. PMID- 4218565 TI - Application of laminar flow (clean work bench) for purifying the atmosphere. PMID- 4218566 TI - Comparative studies on culture media used for sterility testing. PMID- 4218567 TI - Functionally balanced nomograms for reading the interdependence of PO2 and HbO2 in some laboratory animals. PMID- 4218568 TI - Mechanism of the action of some antithyroid substances: influence of methylmercaptoimidazole on the enzyme activities in the tissues of thyroidectomised guinea-pigs with suppressed secretion of the thyrotropic hormone. PMID- 4218569 TI - Some monosaccharide oximes as cholinesterase reactivators following the loading of white rats with parathion. PMID- 4218570 TI - The effects of some protective media during thyroid gland preservation in liquid nitrogen at--196 degrees C. PMID- 4218571 TI - An x-ray investigation of the development of the frontal sinuses in children. PMID- 4218572 TI - Urine excretion of vit. B12 58Co in patients with hepatic cirrhosis previously treated with therapeutic dose- of non-radioactive vit. B12. PMID- 4218573 TI - The synthesis of 113m-In-complex for the scintigraphic study of the kidneys. PMID- 4218574 TI - The ectotympanic bone and origin of higher primates. PMID- 4218575 TI - Changes in facial color associated with pregnancy in patas monkeys. (With 1 color plate). PMID- 4218576 TI - Letter: Effect of dosing technique on absorption of carbaryl. PMID- 4218577 TI - The effect of polychlorinated biphenyls on rat reproduction. PMID- 4218578 TI - Complexes in plasma between light chain kappa immunoglobulins and alpha 1 antitrypsin respectively prealbumin. PMID- 4218579 TI - Studies on cryoprecipitation: covalent structure of a human IgG cryoglobulin and its gelation characteristics. PMID- 4218581 TI - Quantitation of hemoglobins by immunodiffusion: specific antibodies to hemoglobins A1, S and F. PMID- 4218580 TI - A 22S cryomacroglobulin with antibody-like activity. I. Physico-chemical characterization and modification of its cryoproperties. PMID- 4218582 TI - The identification of IgE in human head hair. PMID- 4218583 TI - Carbohydrate composition and complement fixation of human monoclonal IgG. PMID- 4218584 TI - Chemical analyses of cryoglobulins. PMID- 4218585 TI - An improved method for preparation of stable antigen coupled erythrocytes for passive hemolysis. PMID- 4218586 TI - Rabbit immunoglobulin lambda chains: isolation and amino acid sequence of cysteine-containing peptides. PMID- 4218588 TI - Immunochemical studies of human red cell membrane proteins excreted in normal urine. PMID- 4218587 TI - Preferential allotypic expression of anti-hapten response in first and second generation heterozygous rabbits of al,3 allotype. PMID- 4218589 TI - Free and bound carcinoembryonic antigen in neoplasms and in normal adult and fetal tissue. PMID- 4218590 TI - The NH2-terminal amino acid sequence of a kappa and a lambda Bence-Jones cryoglobulin. PMID- 4218591 TI - Development of a radioimmunoassay for luteotropin releasing hormone (LRH) and thyrotropin releasing hormone (TRH). PMID- 4218592 TI - The calculation of antigen concentrations in the single radial immunodiffusion. PMID- 4218594 TI - Immunoglobulin synthesis in tumors of human lymphoid origin serially transplantable in the neonatal Syrian hamster. PMID- 4218593 TI - An antiglobulin reagent labelled with colloidal gold for use in electron microscopy. PMID- 4218595 TI - Agglutination of normal and neoplastic human cells by Concanavalin A and Ricinus communis agglutinin. PMID- 4218596 TI - Lactose synthetase induction by hormones in normal and tumorous GR mouse mammary tissue. PMID- 4218597 TI - Random chromosome changes following SA7 transformation of Syrian hamster cells. PMID- 4218598 TI - Herpesvirus ateles: properties of an oncogenic herpesvirus isolated from circulating lymphocytes of spider monkeys (Ateles sp.). PMID- 4218600 TI - Occurrence of tubercle bacilli in urine or menstrual blood in patients at final examination before intended deletion from the dispensary register. PMID- 4218599 TI - Autoimmune diseases and thalidomide. II. Adjuvant disease, experimental allergic encephalomyelitis and experimental allergic neuritis of the rat. PMID- 4218601 TI - Effects of sublethal x-ray doses on the number of ovarioles in Drosophila melanogaster populations. PMID- 4218602 TI - Calf serum content of cell culture grown viral vaccines and possibilities for its reduction. PMID- 4218603 TI - Report of an informal meeting of manufacturers and the control laboratory on influenza vaccine. Held at the National Institute for Biological Standards and Control on Monday, 17 December 1973. PMID- 4218604 TI - Preservation of sera by means of paper discs. PMID- 4218605 TI - Determination of diphtheria antitoxin in guinea-pig sera by the Jensen and tissue culture methods. PMID- 4218606 TI - Baseline karyologic values for primary rhesus and African green monkey cell cultures. PMID- 4218607 TI - [Diverticula of the appendix (apropos of 4 cases)]. PMID- 4218608 TI - von Recklinghausen's disease presenting as the neurofibrosarcoma of the female breast. PMID- 4218609 TI - Educational planning for long-term care administration. PMID- 4218610 TI - Guest editorial: Long term care--a top health priority. PMID- 4218611 TI - Editorial: The role of the administrator in the long term care facility. PMID- 4218612 TI - Guest editorial: Education for the profession--an AUPHA update. PMID- 4218613 TI - Evaluating the organization and management of the long term care program. PMID- 4218614 TI - Editorial: Regulation of long term care. PMID- 4218615 TI - Guest editorial: PSRO review of long term care. PMID- 4218616 TI - Patient care assessment: a managerial strategy. PMID- 4218617 TI - Guest editorial: Physician services and long term care institutions. PMID- 4218619 TI - Aleutian disease--1974. PMID- 4218620 TI - Acute infectious agent arthritis (IAA): a detailed comparison of proved gonococcal and other blood-borne bacterial arthritis. PMID- 4218622 TI - Cell mediated immunity in protein-calorie malnutrition. PMID- 4218621 TI - Social and cultural aspects of hospitalised malnourished children in Jordan. PMID- 4218623 TI - Pathological observations of feline mast cell tumor. PMID- 4218624 TI - [Chemically defined diet in pediatrics]. PMID- 4218625 TI - Mechanism of action of antitumor agents on bacteria. II. Effect of acetyl kidamycin on nucleic acids. PMID- 4218626 TI - [Effective parenteral feeding of patients with stomach cancer in the postoperative period]. PMID- 4218627 TI - [Microflora of patients with skin burns]. PMID- 4218628 TI - [Repeated surgery of the biliary tract]. PMID- 4218629 TI - [Paracholedochal cyst]. PMID- 4218630 TI - [Disc sensitivity to pyopen, garamycin and vibramycin of bacteria isolated from urine]. PMID- 4218632 TI - [Assay of serum transcortin using electroimmunodiffusion. (Preliminary results)]. PMID- 4218631 TI - [Role of the microbiologist in the control of hospital infection]. PMID- 4218633 TI - [Radiotherapy of brain metastases]. PMID- 4218634 TI - [Massive resections of the small intestine; physiopathology and clinical aspects]. PMID- 4218635 TI - [Sulglycotide in the therapy of gastroduodenal ulcer]. PMID- 4218636 TI - On the possibility of in vitro transformation of human peripheral blood lymphocytes by chemical carcinogens. PMID- 4218637 TI - Disseminated herpes simplex in untreated multiple myeloma. Paradox of present concepts of immune defects. AB - A patient with disseminated herpes simplex virus infection, documented by direct immunofluorescence, and untreated multiple myeloma with abnormal immunoglobulins is presented. Reports of infections with intracellular pathogens in myeloma patients are rare, whereas pyogenic infections have been amply documented. Partly in consequence of this, the untreated disease has been thought of as a relatively pure defect in humoral immunity. Review of present knowledge suggests that cell mediated immunity is of paramount importance in combatting and containing infection with this virus. Thus, immune defects in multiple myeloma, and its infectious complications, may be more complex than appreciated by current concepts of this disease based on previously reported cases. PMID- 4218638 TI - [Concentration of the individual immunoglobulin classes in the breast secretion of women in the early puerperium]. PMID- 4218639 TI - [Content of the basic immunoglobulin classes in young children with recurrent respiratory diseases]. PMID- 4218640 TI - [Progress in renutrition in pediatric digestive pathology]. PMID- 4218641 TI - [Letter: HL-A and high serum IgE]. PMID- 4218642 TI - [Recklinghausens disease and phacomatoses: neoplastic dysplasias affecting APUD system]. PMID- 4218643 TI - Effects of insulin and growth hormone on protein synthesis in newborn offspring of protein-energy malnourished rabbits. PMID- 4218644 TI - The effects of trace elements and ethylenediaminetetraacetic acid on the survival of chicks inoculated with Salmonella gallinarum. PMID- 4218646 TI - Action of 5-hydroxytryptamine, histamine and methergoline on phagocytosis. PMID- 4218645 TI - Enzyme derivatives containing reactive groups. II. Immobilization of alpha amylase on human erythrocytes using 5,5 dithiobis (2 nitro benzoic acid) and M maleimidobenzoic acid adducts. PMID- 4218647 TI - Synergistic lethal action of alkylating agents and sodium pentobarbital in the mouse. PMID- 4218649 TI - [Experimental creation of monstrosities of ocular organs by direct methods]. PMID- 4218648 TI - [Study on the inhibition of Streptococcus pyogenes A cultures by tonsils impregnated in vivo with Ospen]. PMID- 4218650 TI - [Caudal cisterna. Its variants and abnormalities]. PMID- 4218651 TI - [Incidence of congenital transmission of Chagas' disease in full term deliveries]. PMID- 4218652 TI - Anti-Trypanosoma cruzi IgM antibodies as serological evidence of recent infection. PMID- 4218653 TI - [Clinical analysis based on subsidiary tests of a patient from which was isolated, 23 years ago, the Y strain of Trypanosoma cruzi]. PMID- 4218654 TI - Recent advances in parenteral alimentation of infants. PMID- 4218655 TI - [Inflammatory rheumatism and Waldenstrom's macroglobulinemia]. AB - Painful articular manifestations occured in 6 out of 256 patients with Waldenstrom's macroglobulinaemia: in all the cases they took the form of subacute oligoarthritis unrelated to rheumatoid illness or gout. Although these 6 cases would appear to be associated, the total number is too small to exclude the possibility of coincidence. In any case, if such articular manifestations do occur, their rarity makes it impractical to use them as a positive diagnostic aid. PMID- 4218656 TI - [IgM monoclonal dysglobulinemia with articular manifestations and neoplasia]. PMID- 4218657 TI - [Rhizomelic pseudo-polyarthritis and Waldenstrom's disease]. PMID- 4218658 TI - Simultaneous insulin immunoassay in sera, heparin-, and EDTA-plasma. PMID- 4218659 TI - [Immunomorphology of sensitization. XII. Immunomorphology of the lung during experimental aerogenic sensitization]. PMID- 4218660 TI - Acid-base status in nonketotic diabetics. PMID- 4218661 TI - Cell agglutinating activities of some enteric bacteria and effects of various factors on bacteria-tumor cell agglutination. PMID- 4218662 TI - [Value of fractioning of the posology in oral treatment of diabetes mellitus]. PMID- 4218663 TI - Sulfate reabsorption by the urinary bladder of Bufo marinus. PMID- 4218665 TI - Letter: Effect of diethylcarbamazine on the filarial skin test. PMID- 4218664 TI - A demonstration of the role of the renal erythropoietic factor in erythropoietin production. PMID- 4218666 TI - Letter: Mebendazole--ineffective against Onchocerca volvulus. PMID- 4218667 TI - Incidence of sarcosporidiosis in sheep in Iran. PMID- 4218668 TI - Role of Australia (Au) antigen in chronic liver disease in infancy and childhood. PMID- 4218669 TI - Foetal medicine. PMID- 4218670 TI - [Changes in the relationships between the numbers of leukocytes, neutrophilic granulocytes and lymphocytes in the blood of fetuses and sucklings]. PMID- 4218672 TI - [Viral gastroenteritis of swine--antibody production in sows in locations with different epizootological courses of the disease]. PMID- 4218671 TI - [Several morphologic signs of the reactivity of swine fetuses]. PMID- 4218673 TI - [Twin calving in several cattle breeds and its effect on future fertility and milk yield]. PMID- 4218674 TI - [Use of the vertical immunodiffusion method for the differential diagnosis of myeloma disease]. PMID- 4218675 TI - [Clinical and epidemiological importance of determining Australia antigen]. PMID- 4218676 TI - [Laboratory requirements in emergency and intermittent haemodialysis: urea and creatine (author's transl)]. PMID- 4218677 TI - [Long-term physiotherapy in chronic bronchitis (author's transl)]. PMID- 4218679 TI - [The effect of dihydroergostin on the blood circulation and venous capacity of the finger]. PMID- 4218678 TI - A comparative golgi sutdy of the neocortex in insectivores and rodents. PMID- 4218680 TI - [Aggressive juvenile ossifying fibroma of the left mandible]. PMID- 4218681 TI - [The significance of experimental alterations in the epiphyseal growth plates of rats for growing and adult humans (author's transl)]. PMID- 4218682 TI - [The renal osteodystrophy of bilateral nephrectomised patients with preoperative normal skeletal histology during chronic hemodialysis (author's transl)]. PMID- 4218684 TI - [Proceedings: Recirculation following cerebral ischemia lasting one hour]. PMID- 4218683 TI - [Nonossifying fibroma of bone (author's transl)]. PMID- 4218685 TI - Severe neonatal jaundice. Analysis of possible associated factors in infants from Accra. PMID- 4218686 TI - Clinical experience with dihydroergocristine-reserpine-clopamide combination (brinerdin) in Ghanaian hypertensives. PMID- 4218687 TI - A simple laboratory diagnosis of meningitis: the causative organism and therapy. PMID- 4218688 TI - Remission of severe diabetes mellitus in a Ghanaian. PMID- 4218689 TI - [Conversion of parenterally administered sugars during postoperative stage]. PMID- 4218690 TI - [Artificial feeding of patients suffering from severe skull and brain injuries]. PMID- 4218691 TI - [Pseudomonad hospitalism (author's transl)]. PMID- 4218693 TI - Myoglobin in homozygous beta-thalassaemia. PMID- 4218692 TI - [Isolation of fetal Rh factors in the blood of pregnant women]. PMID- 4218695 TI - Increased capillary permeability in haemophilia and afibrinogenaemia. PMID- 4218694 TI - High transfusion regime in the management of reproductive wastage and maternal complications of pregnancy in thalassaemia major. PMID- 4218697 TI - Myeloma in a case of hodgkin's disease. PMID- 4218696 TI - Antiglobulin antibodies and anticomplementary factors in hepatitis b antigenaemia. PMID- 4218698 TI - Thrombotic thrombocytopenic purpura with autoimmune pancytopenia. PMID- 4218699 TI - [Histochemical evidence of aminotransferases. I. Method of histochemical demonstration of a few aminotransferases in rat organs (author's transl)]. PMID- 4218700 TI - The localization of alkaline phosphatase activity in the rat small intestinal epithelium after fat and protein feeding. PMID- 4218701 TI - Distribution of lipase (EC 3.1.1.3) in the digestive system of two teleost fishes. PMID- 4218702 TI - Localisation of alkaline phosphatase activity in the ovary of the percoid teleost fish Nandus. PMID- 4218703 TI - Histochemical localization of esterase and lipase in the digestive system of two teleost fishes. PMID- 4218704 TI - [Electronmicroscopic investigation of the surface charge of the lens epithelial cells of cattle in the short time culture (author's transl)]. PMID- 4218705 TI - Location of steroid hormone production in the ovary of Trachurus mediterraneus. PMID- 4218706 TI - Repair of the post-extraction sockets in marmosets (Callithrix jacchus). PMID- 4218707 TI - [Folkloristic psychiatry in Chile: anthropological study of 6 disease entities]. PMID- 4218708 TI - Treatment of biliary atresia. PMID- 4218709 TI - Surgical approach to nutritional problems. PMID- 4218710 TI - Parrallel enzymatic changes detectable in cancer and schizophrenic patients as a possible result of environmental stimulation. PMID- 4218711 TI - Certain experimentally demonstrated connections of the chief sensory trigeminal nucleus in the squirrel monkey Saimiri sciureus. PMID- 4218712 TI - [Extra-hepatic biliary tract in patients, carriers of Chagas' disease "megas"]. PMID- 4218713 TI - [Statistical study of serum immunoglobulin levels in burned patients]. PMID- 4218714 TI - [Study of urinary elimination of amino acids during parenteral feeding with a complete nutriment, Trivemil (EB 51)]. PMID- 4218715 TI - [Sjogren's syndrome with pseudolymphoma]. PMID- 4218716 TI - [Dysimmune rheumatism in Raynaud's syndrome (inflammatory rheumatism, Raynaud's syndrome, speckled antinuclear factors and anti-ribonucleoprotein antibody): a new syndrome?]. PMID- 4218717 TI - Cytochemical changes in conjugants and exconjugants of Blepharisma intermedium. PMID- 4218718 TI - [Conditions for a selective precipitation of serum IgM with a synthetic melanin (author's transl)]. PMID- 4218719 TI - Immunoglobulin biosynthesis and its control. PMID- 4218720 TI - Rabbit heavy chain allotypes: are they subjected to selective pressure? PMID- 4218721 TI - Choline incorporation into phospholipids by microsomal fractions from L5178Y lymphoma. PMID- 4218722 TI - Transport of folate compounds into Lactobacillus Casei. PMID- 4218723 TI - Changes in serotonin (5-HT) concentrations in brain tissue of rats with adjuvant induced polyarthritis. PMID- 4218724 TI - Optimal conditions for the hydrolysis of seclazone by rat hepatic microsomes. PMID- 4218725 TI - Effects of bacterial cardio-stimulating substance on cardiac metabolism in dogs. PMID- 4218726 TI - [Study of monophasic action potentials of the myocardium by endocavitary approach. Methodology]. AB - The suction electrode makes it possible to record the monophasic action potentials (MAP) of the heart in situ. The technical characteristics of the tripolar electrode which we use are described. The O phase of the MAP is more prolonged than that of the intracellular action potential, but makes it possible to demonstrate the time of arrival of the activation wave in front of the exploring electrode. The phase 1-2 and the phase 3 have their characteristic contour in the right atrium and ventricle. The duration of repolarization makes it possible to assess the refractory period of different parts of the atrial and ventricular myocardium. The relatively simple and harmless method of recording of the monophasic action potentials by the endocardial route, both in the animal and in man, widens our investigation field of electrophysiology applied to the study of arrhythmias, of the repolarization disturbances and of the drug influences on the cell activity. PMID- 4218727 TI - [Nonevolutive aspect of changes in aortocoronary grafts]. AB - An accurate and objective knowledge of the evolution of the aorta-to-coronary grafts is essential in order to establish the rationale of the role of this surgery in the treatment of the coronary artery disease. Serial angiographies of the venous grafts were performed 15 days, one year and approximately 3 years after operation in 74 patients (101 grafts). The graft occlusion rate was 10% in the initial study, more than 20% in the second examination and 6% in the third examination. Moreover, a significant number of pervious grafts have shown, between 2 weeks and one year, a diffuse or segmentary reduction of their lumen. Nevertheless, besides a few grafts with severe stenoses which became occluded, these changes did not progress between one and three years. Therefore, sub intimal fibrous hyperplasia, responsible for the structure changes of the grafts, does not seem to be a slowly evolutive pathologic process but seems rather to stabilize itself after one year. PMID- 4218728 TI - [Classification of primary myocardiopathies according to cineangiographic and hemodynamic data]. AB - Based on the data of high-speed, synchronous, biplane left cineventriculography and of haemodynamic examination, a physio-pathological classification for primary cardiomyopathies is put forward. Besides obstructive cardiomyopathies, three groups were individualized: hyperkinetic hypertrophic cardiomyopathy, hypokinetic hypertrophic and hypokinetic hypotrophic cardiomyopathies. The individuality of each group was discussed together with its eventual evolution from one the other. A better defined therapeutic attitude should result from this classification which therefore has a practical interest as well. PMID- 4218729 TI - [Study of left ventricular function in valvular cardiopathies (mitral insufficiency and aortic insufficiency]. AB - A study of the left ventricular function based on the haemodynamic data combined with those provided by biplane cineangiography was performed in 35 cases with left ventricular volume overload (20 cases of mitral incompetence and 15 of aortic insufficiency). The importance of the haemodynamic changes and of the adaptation mechanisms set up were described. The more intense dilatation hypertrophy of aortic incompetence than of mitral incompetence plays an essential part. The role of Starling's mechanism is underlined. Estimation of the contractile value of the myocardium, taken into account the mechanical overload and the conditions of late-diastolic lengthening of the fibre and of impedance to left ventricular ejection was determined. An obvious myocardial failure, demonstrated in approximately one third of the cases, by determination of some contractility indices estimated in the ejection phase, Vf sigma max in particular, the only one valid in the presence of valvular regurgitation. In the other cases, the moderate decrease of myocardial contractility was masked by compensatory mechanisms. PMID- 4218730 TI - [Effects of selective beta adrenergic block on myocardial contractility. Relative role of negative inotropic and chronotropic effects]. AB - Left ventricular function was studied in 15 patients both before and after intravenous administration of Practolol (an agent blocking selectively the heart beta-adrenergic receptors (beta 1)), while the heart rate was constant by right atrial pacing. The negative inotropic effect linked to the negative chronotropic effect of the beta-adrenergic blockage, represented approximately one quarter of the overall depression of the contractility. Right atrial pacing determined a decrease of the left ventricular end-diastolic pressure and an increase of the pacing rate by 20% above the spontaneous heart rate, after administration of 30 mg of Practolol, brought the contractility back to its control level. PMID- 4218731 TI - [Atrio-ventricular block in rheumatoid polyarthritis. Histological study of the His-Tawara system. Apropos of 2 cases]. AB - A histological study of the conduction pathways was performed by serial sections in two patients who died with atrio-ventricular block in the course of rhumatoid arthritis. In the first case, the conduction disturbance was preceded by attacks of supra-ventricular paroxysmal tachycardia. The His-Tawara system was wholly infiltrated by a cast of lympho-plamocytes starting from rhumatoid nodules located at the base of both mitral and tricuspid valves and at the root of the aorta. The sinus node was the seat of a common fibrosis. In the second case, the atrio-ventricular block was secondary to amylosis which predominated in the central fibrous node and in the adjacent small coronary vessels. The His-Tawara system was completely destroyed down to its bifurcation. The sinus node was normal. PMID- 4218732 TI - [Ventricular rhythms with normal heart rate in the acute stage of myocardial infarction]. AB - In relation with 25 personal cases, a general review of ventricular rhythms with normal rate observed during the acute stage of myocardial infarction is undertaken. More commonly called "slow VT", this transient and benign arrhythmia occurs within the first 48 hours of infarction. Presence of numerous fusion beats and His potential recordings make it possible to demonstrate its ventricular origin. Its mechanism is variable: in most cases it results from the discharge of an automatic, non-parasystolic, intermittently active focus, more rarely from the discharge of a parasytolic focus and in many cases, the focus is not apparent. Treatment of this arrhythmia should be careful: its benign character often justifies therapeutic abstention. PMID- 4218733 TI - [Valvular prosthesis and anticoagulant treatment]. AB - 67 patients with prosthetic valvular replacement have been followed up for a period ranging from 6 months to 9 1/2 years; the overall number of valves was: 53 mitral, 24 aortic, 10 tricuspid valves. The average age of our patients was young (23.6 years). Many patients, because of their age or by lack of discipline or because of their social condition, had an inefficient anticoagulant treatment; they were subdivided into three groups. Those who stopped their anticoagulant treatment 6, those treatment was inefficient 25; in these two groups, no thrombo embolic accident was noted, those whose treatment was efficient with a prothrombin time permanently lower than or equal to 40%: 36. It is in this very series that three cases of thrombosis occurred, two of which were lethal. Thus, although the indication for an anticoagulant treatment in patients with prosthetic valvar replacement remains indisputable, one may wonder, in front of such results, if there are not other factors, besides anticoagulant treatment, that result in thrombo-embolic accidents. PMID- 4218734 TI - [Chronic pericardial effusion and congenital cardiopathy]. AB - Report of one case of chronic pericardial effusion combined with pulmonary valve stenosis and atrial septal defect in a man aged 31, hospitalized for congestive heart failure. The relationship between these two diseases were studied, and the diagnostic and therapeutic problems posed were studied. PMID- 4218736 TI - [A case of abnormal venous drainage of the whole left lung into the left innominate venous trunk]. AB - In this case, the drainage of all the left lung veins of gathered in a common trunk into the left innominate venous trunk was combined with an atrial septal defect and partition of the left atrium. The rarity of such cases in the literature is due to the fact that it is an uncommon anatomical anomaly and that very often it is symptomless, and therefore does not induce the subjects with this anomaly to seek medical advice. In the case reported, surgical treatment consisted in closing the atrial septal defect, resecting the abnormal left atrial partition and in re-establishing the drainage of the left lung veins into the left atrium through a wide latero-lateral anastomosis with ligature of the abnormal left pulmonary venous trunk as its junction with the left innominate venous trunk. PMID- 4218735 TI - [Abnormal implantation of a coronary artery in a 53-year-old patient. Surgical correction]. AB - In a 53-years old patient complaining of dyspnoea and angina of effort, the coronary arteriography demonstrated ab abnormal implantation of the pulmonary artery into the left coronary-artery. Correlated with the 39 cases of the adolescent and the adult published in the literature, the case reported has some peculiarities: poorness of the auscultatory signs consisting in a mild apical systolic murmur; electrocardiographic pattern of left complete bundle-branch block; presence of massive calcifications visible by X-ray into the lateral, wall of the left ventricle. Coronary arteriography and catherization made it possible to demonstrate a left-to-right shunt by backward-flow revascularization of the left coronary artery starting from the right coronary artery. A simple suture of the implantation foramen of the abnomal coronary artery resulted in increased pressure into this artery and was followed by disappearance of angina during an observation period of 5 months. PMID- 4218737 TI - [Benign vascular tumor of the heart. Apropos of a case of vascular hamartoma of the left ventrilce successfully operated on]. PMID- 4218738 TI - [One-direction atrio-ventricular blocks. Study by His electrogram recording]. PMID- 4218739 TI - [Do slow reciprocal rhythms exist?]. PMID- 4218740 TI - [Exercise electrocardiogram in a healthy population with a high coronary risk]. PMID- 4218744 TI - [Significance of atheromatous stenoses of the common trunk of the left coronary artery]. PMID- 4218742 TI - [Contribution of vascular filling to the hemodynamic diagnosis of cardiac insufficiency]. PMID- 4218741 TI - [Correlation between the electrocardiographic data of a submaximal exercise test and coronarography]. PMID- 4218743 TI - [Surgical treatment of obstructive cardiopathies. Apropos of 5 cases of mitral valve replacement by a Bjork valve]. PMID- 4218745 TI - [Block of sentinel pacemakers by muscle potentials]. PMID- 4218746 TI - [Diffuse aneurysms of the coronary arteries. Apropos of 3 cases]. PMID- 4218747 TI - [Compartmental study of the left ventricle ejection fraction by direct injection of an isotope with a short life]. PMID- 4218748 TI - [Should one apply total or developed intraventricular pressure in the calculation of the isovolumetric pressure-velocity relationship of the left ventricle in man]. PMID- 4218749 TI - [Postoperative electric and enzymatic changes during valve replacements (correlations with method for preserving the myocardium)]. PMID- 4218751 TI - [Sarcosporidia infection of the central nervous system in sheep, differential diagnosis from protozoan infections]. PMID- 4218750 TI - [Emergency closure on the 6th day of a septal perforation and resection of an antero-lateral infarction on the 10th day of its course]. PMID- 4218752 TI - [Diverticulum of the rectum. Report of two cases]. PMID- 4218753 TI - Peribiliary portal system in the monkey liver as evidenced by the injection replica scanning electron microscope method. PMID- 4218754 TI - [Method of intravital perfusion fixation of rat liver for electron microscopic studies]. PMID- 4218755 TI - [Embryotoxic and teratogenic effort of 7,12-dimethylbenz(a)anthracene on rat embryos]. PMID- 4218757 TI - Acquired diverticula of the vermiform appendix. PMID- 4218758 TI - Burns and the use of silver sulphadiazine. PMID- 4218756 TI - [Rhino-surgical tasks in the orbit (author's transl)]. PMID- 4218759 TI - The successful conservative management of high-output entero-cutaneous fistulae. PMID- 4218760 TI - Some unusual aspects of clefts of the lip. PMID- 4218761 TI - [Treatment of patients wearing pacemakers]. PMID- 4218763 TI - The pathogenesis of muscular dystrophy: a review. PMID- 4218762 TI - [Specificity of the intracellular RNAse II from Aspergillus clavatus]. PMID- 4218764 TI - Genetics of French-Canadians. PMID- 4218765 TI - Genetic marker systems in Philippine Negritos. PMID- 4218767 TI - Treatment of mucopolysaccharidoses. PMID- 4218766 TI - Hip arthrography in the epiphyseal dysplasias. PMID- 4218768 TI - Comments on the plasma treatment of the mucopolysaccharidoses. PMID- 4218770 TI - Histologic studies in the chondrodystrophies. PMID- 4218769 TI - Beta-glucuronidase deficiency (mucopolysaccharidosis type VII). PMID- 4218771 TI - A possible etiologic mechanism for fibrodysplasia ossificans progressiva. PMID- 4218772 TI - Ultrastructure of cartilage in chondrodystrophies. PMID- 4218773 TI - Fine structure of skeletal dysplasia as seen in pseudoachondroplastic spondyloepiphyseal dysplasia and asphyxiating thoracic dystrophy. PMID- 4218775 TI - Spondyloepiphyseal dysplasia-unclassified type. PMID- 4218774 TI - Pseudoachondroplastic dysplasia: pathodynamics and management. PMID- 4218776 TI - Spondyloepiphyseal dysplasia congenita. PMID- 4218777 TI - Spondyloepiphyseal dysplasia tarda, X-linked form. PMID- 4218778 TI - Unclassified short stature, probably mild spondyloepiphyseal dysplasia. PMID- 4218779 TI - Distinctive spondyloepiphyseal dysplasia in father and three children. PMID- 4218780 TI - Unclassified short stature, possibly spondyloepiphyseal dysplasia, possibly multiple epiphyseal dysplasia, in father and daughter. PMID- 4218781 TI - Pleomorphism of hip disease in a large kinship with spondylo- and multiple epiphyseal dysplasia. PMID- 4218782 TI - Spondylometaphyseal dysplasia (Brazilian type). PMID- 4218783 TI - Simultaneous parastremmatic dwarfism and osteogenesis imperfecta. PMID- 4218784 TI - Mucopolysaccharidosis: possible Hurler/Scheie genetic compound (MPS I-H/S). PMID- 4218785 TI - The Morquio syndrome (MPS IV). PMID- 4218786 TI - Morquio syndrome in a woman with two normal children. PMID- 4218787 TI - Two brothers with nonkeratan-sulfate-excreting Morquio syndrome. PMID- 4218788 TI - Mucolipidosis II (I-cell disease). PMID- 4218789 TI - Mucolipidosis, probably a new variant with joint deformity and peripheral nerve dysfunction. PMID- 4218790 TI - Proximal focal femoral deficiency (familial). PMID- 4218791 TI - Fibrodysplasia ossificans progressiva (FOP) treated with diphosphonate. PMID- 4218792 TI - Blood viscosity in healthy men, measured in rhombospheroid viscometer on EDTA blood. A comparison with the cone-in-cone viscometer data and those of Copley. PMID- 4218793 TI - [Heterogenetic antigens of the agents of particularly dangerous infections and human intestinal tissue]. PMID- 4218794 TI - [The role of microbial flora in the induction of intestinal tumors in rats]. PMID- 4218795 TI - [The life span and causes of death in white rats subjected to prolonged ethylenediaminotetraacetate feeding]. PMID- 4218796 TI - A scale of disability and prognosis in long-term mental illness. PMID- 4218797 TI - Collateral inhibition in the sensorimotor cortex of the cat and the squirrel monkey - its role in control of neuronal discharges. PMID- 4218798 TI - Effects of ablating the striate cortex on a successive pattern discrimination:further study of the visual system in the tree shrew (Tupaia glis). PMID- 4218799 TI - Cerebral hemisphere: primary layering and inner structural interrelationships. PMID- 4218800 TI - Concurrent measurement of left ventricular dPdtmax, isometric contractile force and cardiac loading in the intact monkey. PMID- 4218801 TI - Nervous mechanisms involved in experimentally induced extrapyramidal disturbances. PMID- 4218802 TI - Possible role of cerebellar circuits in parkinsonian symptoms. PMID- 4218803 TI - Interpretation of hyperlipidemias. PMID- 4218805 TI - Triazolam: a sleep laboratory study of a new benzodiazepine hypnotic. PMID- 4218804 TI - Prindolol (Visken) and alprenolol (Aptin) in angina pectoris: a comparative clinical study with special reference to ergometer working capacity tests. PMID- 4218806 TI - A multicentric trial of a new synthetic antibacterial in urinary infections. PMID- 4218807 TI - Sex-chromosome pairing and male fertility. PMID- 4218808 TI - [Quantitative determination of protein excretion in the hepatic bile]. PMID- 4218810 TI - [Experiences with duodenoscopy]. PMID- 4218809 TI - [Diagnosis and prognosis of esophageal carcinoma]. PMID- 4218811 TI - Toxicodynamics of aroclor 1254 in the male rat. PMID- 4218813 TI - In vitro drug selection in antineoplastic chemotherapy. PMID- 4218812 TI - Cytostatic activity of chlamydocin, a rapidly inactivated cyclic tetrapeptide. PMID- 4218814 TI - The haematopoietic stem cell in Rauscher virus-induced erythroblastosis of BALB/c mice. PMID- 4218815 TI - Early abortion in a family planning clinic. PMID- 4218816 TI - Assessment of the health and nutritional standards of infants and preschool children in high density Cairo community. PMID- 4218817 TI - Xylose absorption in protein-calorie malnutrition. PMID- 4218818 TI - Fat absorption in protein-calorie malnutrition. PMID- 4218819 TI - [Action of the new modifier "Kokhedur" on the body]. PMID- 4218821 TI - HL-A phenotype and anti-RhO(D) immunization. PMID- 4218820 TI - [Srapid fluorescence methods of detecting sevin residues in the environment]. PMID- 4218822 TI - Effectiveness of Rh prophylaxis. PMID- 4218824 TI - Preventing the incompatible blood transfusion. PMID- 4218823 TI - Immunization of RhO(D)-negative secundigravidae whose first pregnancy was terminated by induced abortion. PMID- 4218825 TI - Some obvious problems of a developing country. PMID- 4218827 TI - Proceedings: Degradation of thyrotropin-releasing hormone (TRH) by serum and hypothalamic tissue and its inhibition by analogues of TRH. PMID- 4218826 TI - [Preservation of chicken and quinea-pig erthrocytes for the haemagglutination test by "Newcastle disease virus": electron microscopic studies]. PMID- 4218828 TI - Proceedings: Metabolic significance of the two interconvertible forms of M2-type pyruvate kinase. PMID- 4218829 TI - Proceedings: Fractionation of chromatin in sucrose gradients. PMID- 4218830 TI - Proceedings: Immunological relatedness of human and porcine growth hormones. PMID- 4218831 TI - Proceedings: Induction of alpha-glucosidase during the cell cycle of Myxobacter Al-1. PMID- 4218832 TI - Proceedings: The effect of glucose concentration on the interconversion of the two forms of glycogen phosphorylase and of glycogen synthase in isolated rat hepatocytes. PMID- 4218833 TI - Proceedings: Epinephrine binding by rat liver plasma membranes. Effect of guanyl nucleotides and EDTA. PMID- 4218834 TI - Proceedings: The defect in Maroteaux-Lamy disease (mucopolysaccharidosis VI, subtype A): deficiency of N-acetylgalactosamine-4-sulfatase. PMID- 4218835 TI - Proceedings: Aspects of regulation of the pathways for D-glucose 6-phosphate, D galactose, and L-arabinose in Pseudomonas fluorescens. PMID- 4218836 TI - Proceedings: Structural features determining the antibiotic potencies against Bacillus subtilis of the membrane active hop bitter resins. PMID- 4218838 TI - Proceedings: Inhibition of fatty acid biosynthesis with cerulenin and its effects on citrate-Mg-2 transport and macromolecular syntheses in Bacillus subtilis. PMID- 4218837 TI - Proceedings: The complete amino acid sequence of a rat kappa-light chain. PMID- 4218839 TI - [Synthesis of (tyr(OMe)2)thyroliberin, a new analogue of the thyrotropin releasing hormone (author's transl)]. PMID- 4218840 TI - DNA replication continued in isolated nuclei of synchronously growing Physarum polycephalum. PMID- 4218841 TI - [The primary structure of a monoclonal immunoglobulin L-chain of kappa-type, subgroup IV (Bence-Jones protein Len.). A new subgroup of the kappa-type L chain]. PMID- 4218843 TI - Human cyclopia with assiciated anomalies. PMID- 4218842 TI - Distribution of ABO and Rh blood groups among the tibetans. PMID- 4218844 TI - The synthesis, assembly, and secretion of immunoglobulin: a biochemical and genetic approach. PMID- 4218845 TI - Morphology of the primate nasopharynx. PMID- 4218846 TI - The role of cartilage in long bone growth: a reappraisal. PMID- 4218847 TI - Studies on the biosynthesis of beta-lactam antibiotics. (part)I. Stereo-specific syntheses of (2RS,3S)-[4,4,4-2-H3]-, (2RS,3S)-[4-3-H]-,(RS,3R)- [4-3-H]-, and (2RS,3S)-[4-13C]-valine. Incorporation of (2RS,3S)-[4-13C]- valine into penicillin V. PMID- 4218848 TI - 3-Hydroxyaflatoxin B1: a new metabolite of in vitro aflatoxin B1 metabolism by Vervet monkey (Cercopithecus aethiops) liver. PMID- 4218849 TI - Studies of common baldness in the stump-tailed macaque. V. Regional difference of testosterone metabolites in the hair follicles. PMID- 4218850 TI - [Kinetics of regression and relapse of Walker carcinosarcoma treated with alkylating agents]. PMID- 4218851 TI - [Application of a kinetic method to the evaluation of the efficacy of combination therapy of lung cancer]. PMID- 4218852 TI - [Nature of parasitism by Bdellvibrio bacteriovorus, Stolp et Starr gen et sp. nov]. PMID- 4218853 TI - [Comparative study of the functions of metal phosphate polymers and condense polyphosphates in Penicillium chrysogenum]. PMID- 4218854 TI - [Photoinduced reactions of pigments of the non-sulfur purple bacterium Rhodospirillum rubrum in the region 400-600 nm]. PMID- 4218855 TI - [Study of the effect of amino acids on the biosynthesis of nisin and on the growth of Streptococcus lactis using the method of mathematical planning of experiments]. PMID- 4218856 TI - [Interaction of phycocyanin and chlorophyll in Aphanizomenon flos-aque cells]. PMID- 4218857 TI - [Prevalence among microorganisms of the ability to synthesize cytokinins]. PMID- 4218858 TI - [Electron microscopic study of the development of the cyanophage A-1L in cells of the blue-green alga Anabaena variabilis]. PMID- 4218859 TI - [Microbiological transformation of herbicides in co-oxidation conditions]. PMID- 4218860 TI - [Taxonomy of CO-oxidizing gram negative bacteria]. PMID- 4218862 TI - [In vitro evaluation of combination antibiotic therapy]. PMID- 4218861 TI - [Clinical studies of streptococcal infections. 1) Hemolytic streptococci in upper respiratory tract]. PMID- 4218863 TI - [Effect of propionylmaridomycin in respiratory infections - a double blind study]. PMID- 4218864 TI - Problems and pitfalls in blood grouping tests for non-parentage. IV. Qualifications of experts. PMID- 4218865 TI - [Malformations of the eye and associated structures, and their treatment]. PMID- 4218867 TI - A histological comparison of the giant cells in the central giant cell granuloma of the jaws and the giant cell tumor of long bone. AB - A histological comparison has been made of the giant cells in 10 cases which had been diagnosed as central giant cell granuloma of the jaws and 10 cases diagnosed as giant cell tumor of long bone. The numbers of nuclei in each of 50 giant cells were counted in the 20 lesions. The giant cells were measured in order to compare their sizes in the respective lesions. It was found that the giant cells of the jaw lesions contained significantly fewer nuclei than those of the lesions in other bones. Secondly it was found that cells in the lesions of long bone have significantly larger dimensions than those in the jaw lesions. There was, however, an area of overlap. It was concluded that these data supported the view that giant cell tumor and giant cell granuloma are distinct entities. Some giant cell lesions of long bones are, however, morphologically indistinguishable from lesions of the jaws; and conversely giant cell lesions of the jaws are indistinguishable from some giant cell lesions of the long bones. It seems possible, therefore, that some jaw lesions are giant cell tumors and that some giant cell lesions outside the jaws are giant cell granulomas. PMID- 4218866 TI - Ultrastructural studies of the dying-back process. II. The sequestration and removal by Schwann cells and oligodendrocytes of organelles from normal and diseases axons. PMID- 4218868 TI - Tissue reactions to two fissure sealant resina. AB - Specimens of polymerized and unpolymerized Nuva-Seal and Alpha-Seal were implanted subcutaneously on polythene rods. Polymerized specimens caused only slightly greater reaction than controls over intervals of from 2 days to 1 year. Unpolymerized specimens caused necrosis, marked inflammatory cell infiltration and granulation tissue formation for up to 1 week but were similar to the controls at 1 year. No reaction to unpolymerized resin painted on the oral mucosa was observed. PMID- 4218869 TI - Leukocyte mediated cytotoxicity of chemically induced rat salivary gland neoplasms. AB - Chemically induced tumors of the rat submaxillary glands were tested for the presence of tumor antigens by in vitro leukocyte mediated cytotoxicity assays. Since it has been reported that the saliva of humans with oral cancer contains markedly elevated levels of secretory antibody, the rats' saliva specimens were also tested for blocking and/or potentiating "antibody" activity. The results indicate that saliva from tumor-bearing animals potentiated tumor cell killing if either the tumor cells or leukocytes were pretreated. The effect was much more marked when tumor cells were pretreated. Furthermore, the addition of saliva to tumor cells imparted an immunologic cross reactivity which was not present with untreated tumor cells. Control saliva occasionally produced a similar effect, but not as consistently or with the potency of saliva from tumor-bearing animals. Heat inactivation did not abrogate this potentiation. It is inferred that this may indicate a new system of immunologic surveillance, i.e. arming or potentiation of leukocytes by soluble tumor antigens in glandular secretions. PMID- 4218870 TI - In vivo calcification of implanted bone cells. AB - Bone cells raised in cell culture from the osteogenic cells of newborn rat calvaria were reimplanted in the same species of animals from which the cells were derived. The cells were sealed in Teflon rings containing Millipore filters over both ends. Evidence of calcification occurred inside the implanted ring chambers at 118 and 279 days following implantation in vivo. The calcified matrix produced by the cells had a pattern reminiscent of membranous bone production. PMID- 4218871 TI - Pharmacology and physiology of stereotyped behavior. PMID- 4218872 TI - Dopamine and the pharmacology of schizophrenia: the state of the evidence. PMID- 4218873 TI - Localization of the noradrenergic nervous system in human brain. PMID- 4218874 TI - Microbiological studies in submarines. Ecology of Meningococci in symptomless carriers. PMID- 4218875 TI - Multiple ureteral diverticula. PMID- 4218876 TI - [Myeloma and macroglobulinemia - lists of statistics pertinent to diagnosis]. PMID- 4218878 TI - Binding properties of the plant photoreceptor phytochrome to membranes. PMID- 4218877 TI - Biochemical characterization of the golgi complex of mammalian cells. PMID- 4218879 TI - Human aortic laceration secondary to impact. PMID- 4218880 TI - [Results of postoperative irradiation of lung neoplasms]. PMID- 4218882 TI - [Integral absorbed dose in neutron-capture therapy]. PMID- 4218881 TI - [Use of high energy protons in the combination treatment of cervix neoplasms]. PMID- 4218883 TI - [Calculation of dose fields for electron irradiation in homogenous media]. PMID- 4218884 TI - [Principal results and outlook for scientific studies in the field of radiation and combined therapy of malignant neoplasms (based on materials from the Scientific Research Institute of Medical Radiology, AMS USSR, 1967-1972)]. PMID- 4218885 TI - [Radiation reactions and complications in combination radiotherapy of cervix neoplasms]. PMID- 4218886 TI - [State of hematopoiesis in monkeys at remote periods following acute irradiation]. PMID- 4218887 TI - [External respiration in lung cancer patients during preoperative 25 MeV betatron irradiation]. PMID- 4218888 TI - [Blood pyruvate and lactate levels during combination therapy of lung, esophageal and stomach cancer]. PMID- 4218889 TI - [Clinical study of K42 metabolism by the method of whole body radiometry]. PMID- 4218890 TI - [Study of Na24 and K42 metabolism by the method of whole body radiometry in heart disease patients before and after surgical intervention]. PMID- 4218891 TI - [Chemical and radiochemical methods of studying the transport-organic stage of iodine metabolism]. PMID- 4218892 TI - [Radiation injuries to the bones during megavolt therapy of lung cancer]. PMID- 4218894 TI - Tyrosinase activity and isozymes in B-16 mouse melanomas. AB - B-16 melanomas grown for 13 and 22 days after transplantation in mice were utilized in studies of subcellular distribution of tyrosinase activity and tyrosinase isozyme patterns. The tyrosinase activity utilizing L-tyrosine-14-C was higher in the younger than in the older melanomas. The percent of total activity distributed in the 144,000 g supernatant was 38% for the former and 46% for the latter. Both melanomas had higher percentage of activity confined in the pellet obtained by centrifuging the crude homogenate at 600 g. The digestion of P 600 g pellet by lipase liberated tyrosinase activity which was two fold of the activity originally counted in the pellet. Five isozymes wereobserved in the soluble tyrosinase and two in the solubilized tyrosinase. PMID- 4218893 TI - [Current methods for determination of contents of alpha 1 antitrypsin in the human serum applied in clinico-epidemiological studies]. PMID- 4218895 TI - Use of sensory recombination and somatosensory deafferentation techniques in the investigation of sensory-motor integration. PMID- 4218896 TI - A study of the distribution of polychlorinated biphenyls in the aquatic environment. PMID- 4218897 TI - Analysis of gentamicin in plasma: a comparative study of four methods. PMID- 4218898 TI - Photosynthetic nitrogen fixation by blue-green algae. PMID- 4218899 TI - Oral glucose effect on glycogen synthetase and phosphorylase in heart. Muscle and liver. PMID- 4218900 TI - Profile of American health, 1973. PMID- 4218901 TI - Health and healing practices among five ethnic groups in Miami, Florida. PMID- 4218902 TI - Use of contraceptive services in periods of receipt and nonreceipt of AFDC. PMID- 4218903 TI - Role of lay midwifery in maternity care in a large metropolitan area. PMID- 4218904 TI - Home nursing care program on an Indian reservation. PMID- 4218905 TI - Survival potential and quality of care among free clinics. PMID- 4218906 TI - Outcomes of methadone treatment of 300 innercity addicts. PMID- 4218907 TI - The status of prison health care. A review of the literature. PMID- 4218908 TI - The Public Health Conference on Records and Statistics meeting jointly with The American Association for Vital Records and Public Health Statistics. Highlights of the 15th national meeting. PMID- 4218909 TI - Clinical picture and management of testicular tumours. PMID- 4218910 TI - [Comparison in the admission situation between long-term hospitalized and redischarged schizophrenics]. PMID- 4218911 TI - [Psychopathological syndromes in epilepsy]. PMID- 4218912 TI - [Incidence of arterial hypertension in groups of patients with and without Chagas' disease in the population of a general hospital]. PMID- 4218913 TI - Mutual relations of dorsal and ventral hippocampus with the hypothalamus. I. Hippocampo-hypothalamic projections. PMID- 4218914 TI - [A simple photometric determination of serum albumin]. PMID- 4218916 TI - An automated Rose Bengal agglutination test using the ADAM system. PMID- 4218915 TI - Ocular melanin and the adrenergic innervation to the eye. PMID- 4218917 TI - [Study of the disinfectant effects of gamma rays on bacteria and spores]. PMID- 4218918 TI - [Determination of mycobacteriophages in manure and sewage]. PMID- 4218919 TI - [Changes in organs after vaccination with Br. abortus B-8 strain]. PMID- 4218920 TI - [Amino acid metabolism of Brucella in culture]. PMID- 4218921 TI - [The role of biogenic amines in the pathogenesis of kidney damage]. PMID- 4218922 TI - [Destruction of total messenger RNA in E. coli by treatment with actinomycin D and rifampicin]. PMID- 4218923 TI - [Studies concerning the problem of detecting H-antibodies to Listeria monocytogenes]. PMID- 4218924 TI - [Studies of fluorescent antibody titers and titers of anti-adenovirus sera obtained by other serologic methods]. PMID- 4218925 TI - [Standardization of immunofluorescence. Proff of cytoplasmic (mitochondrial) antibodies]. PMID- 4218926 TI - [Studies of 3 different radiotherapy methods in esophageal carcinoma]. PMID- 4218927 TI - [Endosymoiosis of leafhoppers: A model for the evolution of the eukaryotic cell (author's transl)]. PMID- 4218928 TI - Phylogeny, hologeny and coenogeny, basic concepts of environmental biology. PMID- 4218929 TI - Kinetics and other characteristics of diamine oxidase of pea seedlings. PMID- 4218930 TI - Experimental particle radiation therapy in animal neoplasia. II. Alpha particles versus protons. PMID- 4218931 TI - [Placental serum enzymes in pregnancy. Thermoresistant alkaline phosphatases in normal and pathological pregnancy]. PMID- 4218932 TI - Immunoelectrophoretic determination of two IgM paraprotein variants. PMID- 4218933 TI - [Results of blood group studies carried out at Rackeve (county Pest, Hungary)]. PMID- 4218934 TI - [Blood group studies in malignant neoplastic diseases]. PMID- 4218935 TI - [Procedure for the manufacture of vaccines by means of glutaraldehyde]. PMID- 4218936 TI - Analysis of immunofluorescent preparations based on isolation on DEAE column. PMID- 4218938 TI - Isolation of purified IgA and IgM as by-products of ethanol fractionation. PMID- 4218937 TI - Purification of anti-tetanus human IgG by immunoadsorption. PMID- 4218939 TI - The demonstration of the sensitizing effect of the residual animal serum content of vaccines. PMID- 4218940 TI - [Clomethacillin. Synthesis and antibacterial properties]. PMID- 4218941 TI - Relation of beta-lactamase activity and cellular location to resistance of Enterobacter to penicillins and cephalosporins. AB - The Enterobacter species E. aerogenes, E. cloacae, and E. hafnia were examined for resistance to penicillin and cephalosporin derivatives. All were resistant to benzyl penicillin, ampicillin, 6 [d(-)alpha-amino-p-hydroxyphenylacetamido] penicillanic acid, cephaloridine, cephalothin, and cephalexin. A significant number were sensitive to carbenicillin and 6 [d(-)alpha-carboxy-3 thienylacetamido] penicillanic acid. No differences among the three species were noted. The beta-lactamase activity was cell-bound, and was not released by osmotic shock, toluene treatment, or diphenylamine treatment. It was rarely released into the growth medium. The beta-lactamase activity was primarily directed against cephalosporin derivatives. Synthesis of beta-lactamase was chromosomally mediated. Resistance to ampicillin seemed to be partly related to entry of the molecule into the bacteria since exposure to ethylenediaminetetraacetate lowered the minimal inhibitory concentration. PMID- 4218942 TI - Purification and characteristics of pyocin B39 II. Physical and chemical properties. AB - A purified preparation of pyocin B39 was shown to be homogeneous by disc electrophoresis and ultracentrifugation. Pyocin B39 is an antibacterial agent, protein in nature, and is capable of inhibiting the growth of susceptible cells. It caused a susceptible strain of Pseudomonas aeruginosa to release ultraviolet absorbing material. Pyocin B39 appears to be a protein with a high molecular weight; its sedimentation coefficient is 32.8S. It was destroyed by 7 m urea but was resistant to attack by proteolytic enzymes, such as pepsin and trypsin. From its sedimentation coefficient, a molecular weight of about 2 x 10(6) was calculated. An electron photomicrograph of pyocin B39 revealed it as a rodlike particle, 7.50 pm long and 1.08 pm wide, with striations running at nearly right angles to the axes of the particle. PMID- 4218943 TI - Antagonistic effect of calcium in serum on the activity of tobramycin against Pseudomonas. AB - Physiological concentrations of calcium in serum antagonize the activities of colistin, polymyxin B, and gentamicin against Pseudomonas aeruginosa. Studies were carried out to determine whether tobramycin, a new aminoglycoside antibiotic, is also antagonized by calcium. The activity of tobramycin in vitro was shown to be antagonized by human serum and by physiological concentrations of calcium. The addition of human serum in broth-dilution tests produced a fourfold rise in the minimal inhibitory concentrations of tobramycin for five strains of Pseudomonas. In disc diffusion tests, the addition of calcium to the agar significantly decreased the size of inhibition zones, and the addition of a chelating agent to the agar increased the zone sizes. In a limited comparative study, tobramycin and gentamicin were tested against both light and heavy bacterial inocula of two strains of Pseudomonas. Tobramycin appeared to be antagonized less by serum than was gentamicin at equal antibiotic concentrations. PMID- 4218944 TI - Enhanced toxicity for mice of vincristine and other chemotherapeutic agents with Salmonella typhosa endotoxin and Pseudomonas aeruginosa. AB - The toxicity of Salmonella typhosa 0901 W endotoxin for BALB/c mice was potentiated by the administration of 375 mg of cyclophosphamide per kg, 16 mg of daunomycin per kg, 80 mg of methotrexate per kg, 8 mg of pactamycin per kg, 20 mg of polyinosinic-polycytidylic acid per kg, 1,000 mg of procarbazine per kg, and 1 or 4 mg of vincristine per kg. l-Asparaginase (20,000 units per kg) failed to potentiate endotoxin. Sedation following administration of 45 mg of pentobarbital per kg was prolonged in mice that had received 20,000 units of l-asparaginase per kg, 4 mg of daunomycin per kg, 120 mg of methotrexate per kg, 8 mg of pactamycin per kg, 10 mg of polyinosinic-polycytidylic acid per kg, 500 mg of procarbazine per kg, 2 mg of vincristine per kg, 2 mg of endotoxin per kg, or multiple doses of endotoxin. Mice pretreated with multiple endotoxin doses experienced a significant reduction in their lethal responses due to vincristine-endotoxin combinations; however, endotoxin-pretreated mice were more susceptible to vincristine alone than were normal mice. Simultaneous administration of 1 or 2 mg of vincristine per kg and 1 mg of endotoxin per kg produced greater lethality than sequential regimens. Pretreatment of mice with 65 mg of phenobarbital per kg on 4 consecutive days protected against vincristine-endotoxin combinations. Liver homogenates prepared from mice exposed previously to vincristine were capable of inactivating endotoxin. Vincristine lethality was increased by simultaneous administration of heat-killed cells of Pseudomonas aeruginosa isolated from mouse feces. PMID- 4218945 TI - Effect of ethylenediaminetetraacetic acid and related chelating agents on whole cells of gram-negative bacteria. AB - The effects of ethylenediaminetetraacetic acid and of four other chelating agents on seven strains of gram-negative bacteria are described. Changes in viability, cell lysis, and release of intracellular materials from suspensions in various buffers, pH 7.8 or 9.2, were observed. Cyclohexane-1,2-diaminotetraacetic acid was the most toxic compound, whereas iminodiacetic acid and nitrilotriacetic acid had little bactericidal activity. The activity of the five drugs appeared to be related to their chelating ability. Of the bacterial strains used, Pseudomonas aeruginosa NCTC 1999 and NCTC 6750 were the most susceptible, and Klebsiella aerogenes K1 was the most resistant. In contrast, the two strains of P. aeruginosa were the most resistant to the nonchelating antibacterial agents cetrimide, chlorhexidine, and benzalkonium chloride. PMID- 4218946 TI - The aetiology, diagnosis and treatment of amoebic disease. PMID- 4218947 TI - The effect of serotonin and prostaglandins on internal and external carotid blood flow measured simultaneously in the monkey. PMID- 4218948 TI - [Mucosulfatidosis. Study of 3 familial cases]. PMID- 4218949 TI - [Hypopituitarism with diabetes insipidis after tuberculous meningitis. Surgical discovery of 2 tuberculomas]. PMID- 4218950 TI - [Radioimmunoassay of plasma triiodothyroneine in normal and different pathological cases in children]. PMID- 4218951 TI - Functional and morphological observations on the effect of cyclophosphamide on the immune response of the chicken. PMID- 4218952 TI - Origin of the various immunoglobulins in lymph from the popliteal lymph node of sheep before and after antigenic stimulation. PMID- 4218953 TI - Prothrombin isolation and assay. PMID- 4218955 TI - Proteolysis of rabbit immunoglobulin M by papain. AB - 1. Digestion of rabbit immunoglobulin M (IgM) by papain for 5h, in the absence of reducing agent, gives Fabmu and Fc(5)mu fragments in high yield. Shorter periods give fragment Fc(5)mu with one or more Fabmu fragments still attached. 2. Reducing agent in the absence of a denaturant cleaves rabbit IgM into half subunits, each containing one mu chain and one light chain. Digestion by papain in the presence of such a reducing agent destroys the Fcmu domains. PMID- 4218954 TI - Membrane-bound DD-carboxypeptidases from Bacillus megaterium KM general properties, substrate specificity and sensitivity to penicillins, cephalosporins and peptide inhibitors of the activity at pH5. AB - 1. The membrane from Bacillus megaterium KM contained a dd-carboxypeptidase with optimum activity under the following conditions: pH5.2, bivalent cation, 3mm; ionic strength, 40mm; temperature, 35 degrees C. It was inactivated by treatment with p-chloromercuribenzoate but was fairly insensitive to 2-mercaptoethanol. 2. The enzyme was inhibited by penicillins and cephalosporins. The inhibition of this enzyme was partially reversed on dialysis but 0.2m-2-mercaptoethanol could neither prevent nor reverse the inhibition. 3. The enzyme was extremely sensitive to changes in the configuration and size of the side chain of the C-terminal dipeptide of the substrate. An aliphatic side chain of a well-defined length and polarity was required in the residue that precedes the C-terminal dipeptide. 4. The enzyme was inhibited by a wide range of analogues of the peptidic portion of the natural substrate. PMID- 4218956 TI - Kinetic studies on the effect of uridine diphosphate galactose and manganous ions on the reaction between lactose synthetase A protein from human milk and p hydroxymercuribenzoate. AB - The inhibition of lactose synthetase A protein by p-hydroxymercuribenzoate at pH7.5 and 25 degrees C, which involves the reaction of one molecule of inhibitor with each molecule of enzyme, was decreased in rate by UDP-galactose, especially in the presence of Mn(2+). Pseudo-first-order rate constants for the reaction between 0.1mm-p-hydroxymercuribenzoate and free enzyme, the enzyme-UDP-galactose complex and the enzyme-Mn(2+)-UDP-galactose complex were 4.4x10(-2), 1.9x10(-2) and 0.3x10(-2)min(-1) respectively. The results also indicated that dissociation constants for UDP-galactose in the enzyme-UDP-galactose and enzyme-Mn(2+)-UDP galactose complexes were 313 and 16mum respectively, the latter value being similar to the K(m) for UDP-galactose in the lactose synthetase reaction. The protective effect of UDP-galactose and the role of Mn(2+) ions in lactose synthetase are discussed. PMID- 4218957 TI - Biological, proton-magnetic-resonance- and ultraviolet-spectroscopic evidence for a molecular complex of actinomycin D and 10,11-dihydro-3H-naphth (1,2-g)indazol-7 ol. AB - A proton-magnetic-resonance study of the complex formed between actinomycin D and 10,11-dihydro-3H-naphth[1,2-g]indazol-7-ol strongly suggests that the indazole lies above the phenoxazine ring of actinomycin D. The complex can be destroyed by addition of dimethyl sulphoxide or dimethylformamide. The actinomycin D-indazole complex inhibits growth of Pseudomonas fluorescens and raises the thermal denaturation response of DNA. These data support the hypothesis that a molecular complex is formed which readily inhibits cell growth and interacts with DNA. PMID- 4218958 TI - Inhibition by progesterone of the lactogenic effect of prolactin in the pseudopregnant rabbit. PMID- 4218960 TI - Water-soluble metabolites of p-nitrophenol and 1-naphthyl N-methylcarbamate in flies and grass grubs. Formation of glucose phosphate and phosphate conjugates. AB - Metabolites isolated from houseflies dosed with 1-napththol or p-nitrophenol were identified as the phosphate and glucose phosphate conjugates of these phenols by titrations, hydrolysis, ionophoresis, i.r. spectra and mixed melting point. [(3)H]Carbaryl (1-naphthyl N-methylcarbamate) was metabolized by houseflies, blowflies and grass grubs to water-soluble metabolites which had chromatographic and ionophoretic behaviour similar to those of the conjugates of 1-naphthol with glucose, sulphate, phosphate and glucose 6-phosphate. PMID- 4218959 TI - Soluble neutral and acid maltases in the suckling-rat intestine. The effect of cortisol and development. AB - The 100000g supernatants from 13-day-old suckling-rat intestinal homogenates contained 43.5% of the total intestinal maltase activity, compared with 7.1% in weaned adult rats aged 40 days. The soluble maltase activity was separated on Sepharose 4B into two quantitatively equal fractions at pH6.0, one containing a maltase with a neutral pH optimum and the other a maltase with an acid pH optimum. The neutral maltase was shown to be a maltase-glucoamylase identical with membrane-bound maltase-glucoamylase in molecular weight, heat-sensitivity, substrate specificity, K(m) for maltose and K(i) for Tris. The soluble enzyme was induced by cortisol, but the ratio of the soluble to bound enzyme fell during induction. Solubility of the neutral maltase was not accounted for by the action of endogenous proteinases under the preparative conditions used. It is postulated that the soluble neutral maltase is a membrane-dissociated form of the bound enzyme and that the relationship between these two forms is modulated by cortisol. The acid maltase generally resembled acid maltase of liver, muscle and kidney. It was shown to be a maltase-glucoamylase with optimal activity at pH3.0, and molecular weight of 136000 by density-gradient centrifugation. At pH3.0 its K(m) for maltose was 1.5mm. It was inhibited by turanose (K(i)=7.5mm) and Tris (K(i)=5.5mm) but not by p-chloromercuribenzoate or EDTA. Some 55% of its activity was destroyed by heating at 50 degrees C for 10min. The acid maltase closely resembled beta-glucuronidase and acid beta-galactosidase in its distribution in the intestine, response to tissue homogenization in various media, and decrease in activity with cortisol treatment and weaning, indicating that it was a typical lysosomal enzyme concentrated in the ileum. PMID- 4218961 TI - Protein synthesis and breakdown in the mother-cell and forespore compartments during spore morphogenesis in Bacillus megaterium. AB - Recently developed techniques for isolating forespores from bacilli at all stages of spore morphogenesis have been exploited to investigate the contribution of each of the two compartments of the sporulating cell to the overall pattern of protein synthesis and degradation during sporulation in Bacillus megaterium. These studies have shown: (1) that protein synthesis continues in both compartments throughout spore morphogenesis; (2) that the degradation of proteins made at all times during vegetative growth and sporulation is confined to the mother-cell compartment; (3) that proteins synthesized in the mother-cell compartment during sporulation are subsequently degraded more rapidly than proteins synthesized during vegetative growth. This rate of degradation increases the later the proteins are synthesized in the sporulation sequence. Mature spores were disrupted, and the percentage of the total protein in soluble and particulate fractions was determined. Pulse-labelling experiments were performed to investigate the extent to which the proteins of these two fractions are newly synthesized during sporulation. These data were used to calculate the extent of capture of vegetative cell protein at the time of formation of the forespore septum. The value obtained is consistent with evidence from electron micrographs and supports a model for the origin of spore protein in which there is no protein turnover in the developing forespore. PMID- 4218962 TI - [Activation of hepatic glycogen synthetase in rats treated with thyroid hormone]. PMID- 4218963 TI - The accumulation of malachite green stainable phospholipid in rabbit spermatozoa during maturation in the epididymis, and its possible role in capacitation. PMID- 4218964 TI - The characterization of a malachite green stainable, glutaraldehyde extractable phospholipid in rabbit spermatozoa. PMID- 4218965 TI - Mass spectrometry of the methyl esthers of isomeric hydroxychlorobiphenyls- potential metabolites of chlorobiphenyls. PMID- 4218966 TI - [Ocular emboli caused by intra-arterial injection of albumin microspheres: histological study in man and animals]. PMID- 4218967 TI - A simple double immunodiffusion test for typing influenza viruses. AB - The identification of influenza virus type has traditionally been based on the characterization of internal nucleoprotein (NP) antigens by the complement fixation (CF) test. Because this test is complex and time-consuming, it is used only infrequently. In this report we describe a double immunodiffusion (DID) test, which is proposed as a replacement for the CF test for the typing of influenza viruses. The DID test is simple and requires only the allantoic fluid content of a single infected embryonated egg. Virus from the infected fluid is precipitated with mild acid and disrupted by detergent. Anti-NP or anti-matrix protein (MP) antibody is equally effective in most instances for typing influenza isolates by this test. The latter is preferred, however, since it seemed to be slightly more sensitive than anti-NP antibody. PMID- 4218968 TI - Quantitative measurement of precipitating antibodies and standardization of Streptococcus group B antisera by the reverse radial immunodiffusion technique. AB - A comparative study was made of the reverse radial immunodiffusion (RRID) technique and the quantitative precipitin test for determining the amount of precipitable antibodies present in streptococcus group B antisera. The coefficient of correlation between the 2 tests was 0.963 when a purified carbohydrate antigen was used. The results of this study show that: (1) a group B antiserum should contain at least 3 mg of precipitable antibodies per ml to ensure that it will react with acid extracts of group B diagnostic cultures; and (2) the RRID technique is an accurate and simple procedure for determining the amount of precipitable antibody present in an antiserum, and it could be used for the standardization of these diagnostic reagents. A method for preparing the group B carbohydrate antigen used in the RRID and quantitative precipitin tests is described. PMID- 4218969 TI - Prevalence of nonspecific tuberculin sensitivity in certain parts of India. AB - A survey was carried out in certain parts of India to determine the prevalence of nonspecific tuberculin sensitivity. In the temperate zone, villages situated 1 200 m or more above mean sea level showed a markedly lower prevalence than villages in the plains did. In the tropical zone, the prevalence of nonspecific sensitivity was high. The prevalence of infection due to Mycobacterium tuberculosis was much lower than that of nonspecific sensitivity and the rates did not vary greatly in the areas surveyed. PMID- 4218970 TI - [Serologic tests for malaria]. PMID- 4218972 TI - [The internal development and schizogony in cultured cells of Eimeria stiedai (Lindemann 1865) Kisskalt and Hartmann 1907)]. PMID- 4218971 TI - [Synthetic sexual attractants of Lobesia botrana (Schiff) (Lepidoptera Tortricidae), a predator of grapevines]. PMID- 4218973 TI - [The origin of definitive hematopoetic stem cells in bird embryos: experimental analysis using quail-chicken chimeras]. PMID- 4218974 TI - [The effects of gravidity and fasting on the locomotor activity of the migratory cricket of the migratory cricket of Madagascar (solitary phase) in nature]. PMID- 4218975 TI - [The effect of the photoperiod on the diapause of pyralis of corn (Ostrinia nubilais Hbn., Lepidoptera, Pyralididae]. PMID- 4218977 TI - [The development of the stop reaction in the continuous electroencephalogram following natural olfactory stimuli in white rats raised in semi-freedom]. PMID- 4218976 TI - [Osmoregulation and the calcium binding protein (CaBP) of the intestinal and branchial mucosa of the rainbow trout, Salmo gairdnerii]. PMID- 4218978 TI - [Study in organotypic culture of the sex control of gametogenesis in the annelid oligochete Eisena foetida f. typica Sav.; evidence for androgenic activity in testicular tissue in the presence of the central nervous system]. PMID- 4218979 TI - [Thermosensitive birefringence of amyelinic nerves]. PMID- 4218980 TI - [The basics of biokinematics]. PMID- 4218981 TI - [A theoretical basis for the bursts of alpha waves of the electroencephalogram]. PMID- 4218982 TI - [The transformation of the oxidation product of guaiacol obtained in the presence of horseradish peroxidase]. PMID- 4218983 TI - [Metabolism of glucose by a miroorganism of the soil, Sporocytophaga myxococcoides: study of a hexokinase]. PMID- 4218984 TI - [The inducibility of aspartate-ammonium lyase of Pseudomonas fluorescence (type R)]. PMID- 4218985 TI - Squamous metaplasia and respiratory tumors induced by intratracheal installations of 7, 12-dimethylbenz(a)-anthracene in Syrain golden hamsters. PMID- 4218986 TI - A new pharmacological method of host conditioning in order to facilitate in vivo growth of fibroblast-like cells cultivated in vitro. PMID- 4218987 TI - Observations on the organization of the interstitial tissue of the testis and on the occluding cell junctions in the seminiferous epithelium. PMID- 4218988 TI - Prostaglandins and steroidogenesis. PMID- 4218990 TI - Blood group and HL-A specific substances in immune globulin and albumin preparations of human placental origin. PMID- 4218989 TI - [Preparation of human albumin from hemolysed blood from frozen placental extracts. II. Elimination of certain impurities during purification]. PMID- 4218991 TI - [Obtainment of an enriched preparation of IgA and IgM immunoglobulins for therapeutic usage]. PMID- 4218992 TI - Freeze-dried virus antigen containing cells and FITC-conjugated immune sera for virus diagnostic purposes. PMID- 4218993 TI - [European standards with regard to the control of human immunoglobulins by ultracentrifugation]. PMID- 4218994 TI - [A new process of inactivation for preparation of vaccines]. PMID- 4218995 TI - Concentration of normal immunoglobulins in human sera. PMID- 4218996 TI - Isolation and control of human IgA and IgM preparations. PMID- 4218997 TI - [Titers of immunoglobulins (IgG, IgA, IgM, and IgE) after antigenic stimulation in European and African subjects]. PMID- 4218998 TI - [Pathogenesis of aplastic anemia]. PMID- 4218999 TI - Studies on double-stranded RNA synthesized in acute leukemia blast cells. PMID- 4219000 TI - Interaction of concanavalin A with normal and leukemic lymphocytes: binding and agglutination. PMID- 4219001 TI - Splenectomy in early chronic myeloid leukaemia: preliminary report on 37 cases. PMID- 4219002 TI - Congenital dyserythropoietic anemia (CDA), type I. Light and electron microscopy, erythroblastic proliferation, erythrokinetic and cytogenetic studies in one case. PMID- 4219003 TI - Factor-XIII subunits-A and -S in congenital deficiency and in acute myeloblastic leukemia. PMID- 4219004 TI - Virus-like particles in chronic lymphatic leukemia: ultrastructural findings. PMID- 4219005 TI - [Hamartoma of the spleen with hypersplenism]. PMID- 4219006 TI - A hematologist's appraisal of the problem cerebral lymphomas in transplanted patients. A speculative review. PMID- 4219007 TI - Hemopoietic microenvironment in acute leukemia. PMID- 4219008 TI - [Frederick Stohlman Jr. 1926-1974]. PMID- 4219009 TI - Conditions for purification of anti-Brucella antibodies by immunoadsorption and elution. PMID- 4219010 TI - [Parenteral feeding of the clinical patient]. PMID- 4219011 TI - [Nitrogen balance studies in various amino acid infusions]. PMID- 4219012 TI - [The importance of amino acid substitution for the protein metabolism in patients treated by periodical hemodialysis]. PMID- 4219013 TI - [The problems of monitoring fat and carbohydrate metabolism in seriously ill patients treated by partial or total parenteral feeding]. PMID- 4219014 TI - [Utilization of parenteral triglyceride infusions in postoperative and post traumatic care]. PMID- 4219015 TI - [Glucose-fructose; use of these sugars in parenteral feeding]. PMID- 4219016 TI - [Control of drug use in an intensive care hospital]. PMID- 4219017 TI - [Parenteral feeding and a balanced synthetic diet]. PMID- 4219018 TI - [Complete parenteral feeding]. PMID- 4219019 TI - Further studies of human serum albumin in oral fluid. PMID- 4219021 TI - Organization of replicative units in salivary gland chromosome bands. PMID- 4219020 TI - Pyrimidine-sensitive drosophila wing mutants: withered (whd), tilt (tt) and dumpy (dp). PMID- 4219022 TI - Gonococci and gonorrhea, I. Gonococci. PMID- 4219023 TI - Host defenses in protein-calorie malnutrition. PMID- 4219024 TI - [Detection of glycogen and glycogen synthetase activity in the hepatic primordium of chick embryo at early developmental stages]. PMID- 4219025 TI - Studies on the gastrulation of amphibian embryos: pseudopodia in the gastrula of Bufo bufo japonicus and their significance to gastrulation. PMID- 4219027 TI - The microscopy of parotid atrophy after ligation of Stensen's duct. PMID- 4219026 TI - T and B lymphocytes. PMID- 4219028 TI - Proteins of the periodontium. Biochemical studies on the collagen and noncollagenous proteins of human gingivae. PMID- 4219029 TI - An intraoral model used for studies of fluoride incorporation in enamel. PMID- 4219030 TI - The coccidial nature and life-cycle of Sarcocystis. PMID- 4219031 TI - Laboratory studies on cefazolin--anti-inflammatory agent combinations with particular reference to tiaramide. PMID- 4219032 TI - [Treatment of urinary tract infections in children. Clinical experience with minocycline granules (author's transl)]. PMID- 4219033 TI - [Clinical effect of lividomycin on gonorrhea and lividomycin sensitivity of gonococci (author's transl)]. PMID- 4219035 TI - [Thyroid function test by Trilute and Tetralute kit. II. Tetralute]. PMID- 4219034 TI - [Clinical evaluation of prevention of post-operative infection in digestive organ surgery. Blood level of cephalothin following intraperitoneal administration (author's transl)]. PMID- 4219036 TI - [Use of a drug promoting the trophicity of the cervicovaginal mucosa: Trophigil]. PMID- 4219037 TI - [Study using a new ultrafiltration technic of Bence Jones protein in patients with paraproteinemia]. PMID- 4219038 TI - [Problems specific to chemotherapy of intracerebral tumors]. PMID- 4219039 TI - [Use of biolactin, colibacterin and albumin cheese to prevent gastrointestinal disorders in children in nurseries]. PMID- 4219040 TI - [Parenteral hypercaloric feeding in infants affected by chronic malnutrition]. PMID- 4219041 TI - [Precipitin-induced lung diseases in the agricultural environment]. PMID- 4219042 TI - [The effect of gamma-irradiated fruits and juices on the physiologic activity of Saccharomyces ellipsiodeus]. PMID- 4219044 TI - [Use of uninterrupted cultivation to increase the asparaginase and glutaminase activity of Pseudomonas fluorescens AG-69]. PMID- 4219043 TI - [Products of proteolysis obtained with the use of complex enzyme preparations at different pH values]. PMID- 4219045 TI - [The pigment of Actinomyces aureofaciens LSB-2201]. PMID- 4219046 TI - [Sporogenic bacteria--active destroyers of caprolactam]. PMID- 4219047 TI - [Preservation of a culture of Bacillus cereus by lyophilization]. PMID- 4219048 TI - [Selective action of different fractions of the products of thermophilic methane fermentation on various species of lactic acid bacteria]. PMID- 4219049 TI - [Production of protease and streptomycin from the culture liquid of Streptomyces griseus by methanol separation]. PMID- 4219050 TI - [Use of dried amniotic fluid for the adsorption of group agglutinins in antirhesus group O(I), A(II) and B(III) sera]. PMID- 4219051 TI - [Use of radial immunodiffusion in gel for the study of paraproteins]. PMID- 4219052 TI - [Hemodialysis operation in Waldenstrom's macroglobulinemia complicated by renal insufficiency]. PMID- 4219053 TI - [Express method of determining the rhesus factor in a test tube without heating]. PMID- 4219054 TI - [Tuberculosis as a cause of transient serous meningitis in children]. PMID- 4219055 TI - [Use of sodium cromoglycate in asthma]. PMID- 4219056 TI - [Disodium cromoglycate and pulmonary function in the remission of bronchial asthma]. PMID- 4219058 TI - [Studies of the fractionation method of radiation therapy of esophageal carcinoma]. PMID- 4219057 TI - With liberty and psychosis for all. PMID- 4219059 TI - Providing a comprehensive district psychiatric service for the adult mentally ill. Appendix 3. Syndicate 'D' discussion paper. PMID- 4219060 TI - [Pathogenetic aspects of ossifications in the soft tissues during hemophilia]. PMID- 4219061 TI - [Prenatal protein malnutrition and development of the nervous system]. PMID- 4219062 TI - Studies on the rate of diffusion-controlled reactions of enzymes. Spatial factor and force field factor. PMID- 4219063 TI - The phosphate depletion syndrome: relation to caloric intake and phosphate infusion. PMID- 4219064 TI - Prevention of ischemic myocardial contracture (stone heart). PMID- 4219065 TI - Evolution of infarcts during reperfusion experiments in primates. PMID- 4219066 TI - Cerebral etiology of the respiratory distress syndrome: universal response, with prevention by unilateral pulmonary denervation. PMID- 4219067 TI - Species variability in clinical antihuman antithymocyte globulin production: rabbit vs horse AHTG in primate skin graft survival. PMID- 4219068 TI - Intravenous feeding in hepatic failure. PMID- 4219069 TI - Trigeminothalamic projections from nucleus caudalis in primates. PMID- 4219070 TI - Enhancement of peripheral nerve regeneration with triamcinolone after neurorrhaphy. PMID- 4219071 TI - Modification of intestinal fistula output by elemental and intravenous alimentation. PMID- 4219072 TI - Intravenous fat and glycerol: effect of heparin. PMID- 4219073 TI - Reversible inhibition of phagocytosis in anephric uremic patients. PMID- 4219074 TI - Postoperative positive protein balance: accelerated oxidative glucose consumption. PMID- 4219075 TI - Hepatic glucose balance and glucose tolerance during hemorrhagic shock. PMID- 4219076 TI - [The intensity of respiration in infusoria of different sizes]. PMID- 4219077 TI - [A change in the mitochondrial ultrastructure of damaged nerve cells fixed with glutaraldehyde]. PMID- 4219079 TI - [Several patterns in the development of morphotic ""agametic gonads'' following drosophila embryo irradiation with UV rays]. PMID- 4219078 TI - [Mitochondria of frog skeletal muscle fibers: relationship between ultrastructure and fixation conditions, formation of myelin-like figures]. PMID- 4219080 TI - [The ultra-fine structure of ciliary and cortical organoids and several endoplasmic structures of holotrichous infusoria Trachelonema sulcata]. PMID- 4219081 TI - [Habituation in unicellular organisms]. PMID- 4219083 TI - Study of copper metabolism in kinky hair disease (Menkes' disease) and in hepatolenticular degeneration (Wilson's disease) utilizing 67Cu and radioactivity counting in the total body and various tissues. PMID- 4219082 TI - [Microbial aminopeptidase inhibitors and activators that hydrolyze leucyl glycylglycine]. PMID- 4219084 TI - Mapping of functional pathways in brain by autoradiographic survey of local cerebral metabolism. PMID- 4219086 TI - In search of the motor engram: a behavioral study of somatotopic localization in motor cortex of monkey. PMID- 4219085 TI - Diagnosis and treatment of experimental allergic encephalomyelitis in rhesus monkeys. PMID- 4219087 TI - Primate experiments on oral sensation and morphogenesis. PMID- 4219088 TI - Sensation and morphogenesis experimental and clinical findings following functional forward displacement of the mandible. PMID- 4219090 TI - Penicillin and tetracycline sensitivity of Jamaican strains of gonococci. PMID- 4219089 TI - Toxicity of Nerium oleander in the monkey (Cebus apella). PMID- 4219091 TI - [A comparative study of the frequency of purine block occurrence in the ribosomal RNA of several species of bacteria]. PMID- 4219093 TI - [Preparation and application of the antiserum against human saliva]. PMID- 4219092 TI - Production of a rabbit anti-BKN antibody. PMID- 4219094 TI - [Clinical possibilities in the use of radioimmunologic TSH determination]. PMID- 4219096 TI - Effect of a diphosphonate on para-articular ossification after total hip replacement. PMID- 4219095 TI - Endogenous prostaglandins and the initiation of labor. AB - An attempt to define the role of the prostaglandins in human parturition must necessarily be fragmentary at the present time. However, there is no doubt that considerable progress has been made during the last few years and that the prostaglandins have been established as important key intermediates in the complex hormonal and mechanical events integrated in the process. Improved chemical methods for the determination of prostaglandins in body fluids and tissues as well as some evidence of indirect nature have contributed to a better understanding of this complex problem. PMID- 4219098 TI - 'Neuronal fall-out' in the ageing brain: a critical review of the quantitative data. PMID- 4219097 TI - Amantadine. PMID- 4219100 TI - DSCG and hyposensitization. PMID- 4219099 TI - [The pathogenic role of the reagins (author's transl)]. PMID- 4219101 TI - [Is the indication for DSCG limited to pure allergic asthma]. PMID- 4219104 TI - Phase III and health cost controls. No. L-89. PMID- 4219102 TI - [Clinical trial of sodium cromoglycate in allergic and non-allergic asthma and chronic bronchitis]. PMID- 4219103 TI - Disodium cromoglycate, corticoids and bronchodilators in asthma therapy. PMID- 4219105 TI - [Parenteral hyperalimentation]. PMID- 4219106 TI - Skilled nursing - the issues and their impact. PMID- 4219107 TI - [Analysis of bound and free plasma fractions of thyroid hormones in autonomous hot nodule before and after TSH injection (author's transl)]. PMID- 4219108 TI - [Preliminary results of T3 radioimmunoassay. Comparison with others serum parameters in diseases of the thyroid (author's transl)]. PMID- 4219109 TI - [Effects of thyroid hormone on cell proliferation in the amphibian larva (author's transl)]. PMID- 4219110 TI - [Comparative study of free thyroxine determined by dialysis and free thyroxine sephadex index. Application to diagnosis and treatment of thyroid diseases (author's transl)]. PMID- 4219111 TI - [Proceedings: Hypophyso-thyroid response to TRH and erythro-leukocytic enzyme correlations in man (author's transl)]. PMID- 4219112 TI - [Proceedings: Effects of long term administration of thyrotropin-releasing hormone in the baboon (author's transl)]. PMID- 4219113 TI - [Effects of oral TRH on the thyroid function, thyrotropin and prolactin secretion, in 9 normal subjects]. PMID- 4219114 TI - [Proceedings: Unresponsiveness to I-V T.R.H. Comparison with T3 plasma levels (author's transl)]. PMID- 4219115 TI - [Proceedings: Static and dynamic study of plasma prolactin in patients suffering from myxoedema (author's transl)]. PMID- 4219116 TI - The chemotherapy of plasma cell myeloma and related disorders. PMID- 4219117 TI - Substances that attract eosinophils in vitro and in vivo, and that elicit blood eosinophilia. PMID- 4219118 TI - Granuloma formation and its relation to chemotaxis. A discussion of the role of two groups of micro-organisms: the mycobacteria and the anaerobic coryneforms. PMID- 4219119 TI - [The effect of the active acidity of the medium on the growth of Act. aureofaciens and tetracycline biosynthesis]. PMID- 4219120 TI - [Development of resistance to several antibiotics in brucellae during passage in media with antibiotics]. PMID- 4219121 TI - [The effect of p-dimethylaminobenzaldehyde on chlortetracycline production]. PMID- 4219122 TI - [The antiviral activity of the antibiotics beromycin and carminomycin]. PMID- 4219123 TI - [The influence of several diuretics on penicillin circulation in the bodies of rats]. PMID- 4219125 TI - [The relationship between the nitrogen metabolism of P. chrysogenum 194 and its mutant and penicillin biosynthesis]. PMID- 4219124 TI - [The effect of antibiotics of the anthracycline group--carminomycin and beromycin -on the immunologic reactivity of the body]. PMID- 4219126 TI - [Experimental purulent meningitis and its treatment with antibiotics]. PMID- 4219127 TI - [Use of getamicin in reconstructive surgery]. PMID- 4219128 TI - [Cytological observations on 2 characteristic elements of the struce of the multiple testis in urodele amphibians: reserve spermatogonia and columnar epithelium]. PMID- 4219129 TI - [Critical study of reactions furnished by routine peripheral bacteriological sampling in newborn infants]. PMID- 4219130 TI - [2 further cases of Dyggve-Melchior-Clausen syndrome with hypoplasia of the odontoid apophysis and spinal compression]. PMID- 4219131 TI - [Parenteral hyperalimentation. New approach to intensive therapy of the surgical patient]. PMID- 4219132 TI - [Congenital cataract and its association with other eye abnormalities]. PMID- 4219133 TI - Adjuvant effects of oral microorganisms on the immunological responses. PMID- 4219134 TI - Transport of intravenously administered horseradish peroxidase into the rat submaxillary saliva. PMID- 4219135 TI - Affinity labelling of the binding site of rabbit antibody. Evidence for the involvement of the hypervariable regions of the heavy chain. AB - The binding sites of rabbit antibodies with affinity for the haptenic group 4 azido-2-nitrophenyl-lysine have been specifically labelled by photolysis of the hapten-antibody complex. The extent of covalent labelling was 0.5-0.9mol of hapten bound/mol of antibody and, by using an immunoadsorbent, antibody with 1.3mol of hapten/mol was obtained. The antibody was specifically labelled in the binding site and the ratio of labelling of heavy and light chains was in the range 3.3-5.0. The labelled heavy chains were cleaved by CNBr treatment and after reduction and alkylation of the intrachain bonds, were digested with trypsin. Evidence is presented that two regions of the heavy chain, positions 29-34 and 95 114, together contain about 80% of the label on the heavy chain; these two regions respectively include two of the hypervariable regions of rabbit heavy chain. PMID- 4219136 TI - Fractionation of nucleic acids from Penicillium chrysogenum and associated ribonucleic acid viruses by selective exclusion and retention in agarose gels. AB - Double-stranded nucleic acids from a strain of Penicillium chrysogenum containing RNA viruses were isolated by agarose-gel filtration, and separated into DNA and double-stranded RNA fractions by agarose-gel chromatography in 2.5m-NaCl. The DNA fraction contained less than 1% alkali-labile polynucleotides, and sedimented homogeneously at 8-10S in alkaline sucrose gradients. In CsCl gradients it tended to band in the density region of 1.66-1.72g/ml. It had a ;melting' temperature (T(m)) of 75 degrees C in 0.015m-NaCl-0.0015m-trisodium citrate, corresponding to 51.5mol% of G+C. The double-stranded RNA fraction did not contain detectable DNA. It could not band in CsCl up to a density of 1.78g/ml, and mainly consisted of a 14-15S RNA species with a T(m) of 88.5 degrees C in the above solvent, and a G+C content of 49.3 mol%. PMID- 4219137 TI - The amine oxidases of human placenta and pregnancy plasma. AB - 1. The purification of monoamine oxidase and diamine oxidase from normal human term placental tissue is described. 2. The properties of these enzymes are reported and compared with the properties of unpurified human pregnancy plasma. 3. This comparison shows that the amine oxidase of pregnancy plasma has properties corresponding to purified placental diamine oxidase, suggesting a placental origin for the plasma enzyme system. 4. Detailed kinetic study of the purified placental diamine oxidase suggests that it has a Ping Pong sequence, a mechanism of action and rate-limiting step similar to the diamine oxidase of pig kidney. 5. It is suggested that the enzyme system is important in protecting the foeto-placental unit from excesses of biogenic amines. PMID- 4219138 TI - The inhibition of human placental diamine oxidase by substrate analogues. AB - 1. The oxidation of p-dimethylaminomethylbenzylamine by purified placental diamine oxidase was followed by measuring the change in E(250) caused by the production of p-dimethylaminomethylbenzaldehyde. 2. The inhibition of this reaction by substrate analogues such as isothiouronium, guanidinium, dimethylsulphonium and trimethylammonium compounds was extensively studied. 3. The type and degree of inhibition by mono- and bis-onium compounds is described, and a theory is developed to explain the type of inhibition produced. PMID- 4219139 TI - Stimulation of microsomal uridine diphosphate glucuronyltransferase by glucuronic acid derivatives. AB - The glucuronic acid adducts of 1-naphthol, 2-naphthol and 4-methylumbelliferone activate microsomal UDP-glucuronyltransferase (EC 2.4.1.17) when the enzyme is assayed with p-nitrophenol as aglycone. Phenyl glucuronide and oestriol 3beta glucuronide also activate UDP-glucuronyltransferase. but to a lesser extent. Activation by glucuronides is not dependent on metal ions, but is blocked by prior treatment of microsomal fractions with p-chloromercuribenzoate. The kinetic mechanism of activation is concluded to be an increase in the affinity of the enzyme for UDP-glucuronic acid. Activation by 1-naphthyl glucuronide, at high concentrations of p-nitrophenol, is not affected by 1-naphthol. Apparently 1 naphthyl glucuronide activates the preparation by binding at a site that is separate from the site of glucuronidation of 1-naphthol. Further evidence for the existence of distinct effector sites for the glucuronides was provided by the finding that activation by glucuronides is inhibited competitively by aglycone glucosides. These glucosides do not inhibit the rate of glucuronidation of p nitrophenol in the absence of glucuronide adducts, nor do they alter the rate of glucuronidation of 1-naphthol. When UDP-glucuronyltransferase is assayed with 1 naphthol as aglycone it is activated by p-nitrophenyl glucuronide, 4-methyl umbelliferyl glucuronide and under appropriate conditions by its own glucuronide. These activations are similarly inhibited by aglycone glucosides. p-Nitrophenyl glucuronide also stimulates the rate of glucuronidation of o-aminophenol, o aminobenzoate and bilirubin. PMID- 4219140 TI - Identical 3'-terminal octanucleotide sequence in 18S ribosomal ribonucleic acid from different eukaryotes. A proposed role for this sequence in the recognition of terminator codons. AB - The 3'-terminal sequence of 18S ribosomal RNA from Drosophila melanogaster and Saccharomyces cerevisiae was determined by stepwise degradation from the 3' terminus and labelling with [(3)H]isoniazid. The sequence G-A-U-C-A-U-U-A(OH) was found at the 3'-terminus of both 18S rRNA species. Less extensive data for 18S RNA from a number of other eukaryotes are consistent with the same 3'-terminal sequence, and an identical sequence has previously been reported for the 3'-end of rabbit reticulocyte 18S rRNA (Hunt, 1970). These results suggest that the base sequence in this region is strongly conserved and may be identical in all eukaryotes. As the 3'-terminal hexanucleotide is complementary to eukaryotic terminator codons we discuss the possibility that the 3'-end of 18S rRNA may have a direct base-pairing role in the termination of protein synthesis. PMID- 4219141 TI - Studies on the 3'-terminal sequences of the large ribosomal ribonucleic acid of different eukaryotes and those associated with "hidden" breaks in heart dissociable insects 26S ribonucleic acid. AB - The 3'-terminal sequences associated with the large rRNA complex from a range of eukaryotes were determined after pancreatic or T(1)-ribonuclease digestion of RNA terminally labelled with [(3)H]isoniazid. In all higher eukaryotes examined except Drosophila melanogaster, the 3'-terminal sequences Y-G-U(OH) and G-C-U(OH) were demonstrated for the large RNA component(s) and for 6S RNA respectively. The 3'-terminal sequence of Saccharomyces cerevisiae 26S RNA was Y-G-U(OH) and that of 6S RNA Y-A-U-U-U(OH). Three 3'-terminal sequences were found in equimolar amounts in the heat-dissociable 26S rRNA characteristic of insect ribosomes. These were Y-G-U-G-U(OH), Y-C-G-U(OH) and G-C-U(OH) for cultured Antheraea eucalypti cells, Y-G-U(OH), Y-G-U(OH) and G-C-U(OH) for Galleria mellonella larvae and Y-C-G-A(OH), Y-G-U-A(OH) and G-Y-U-G(OH) for Drosophila melanogaster flies. Thus the introduction of the central scission in insect 26S rRNA results in the generation of a unique 3'-terminus and does not arise from random cleavage of the polynucleotide chain. PMID- 4219142 TI - [Demonstration of staphylococcal enterotoxins by polyacrylamide gel immunodiffusion]. AB - The use of a polyacrylamide gel in immunodiffusion reactions and particularly in the staphylococcal antiserum-enterotoxin precipitation reaction, is set forth. The advantages shown by this gel are: possibility to obtain different gel lattices, tansparency, mechanical resistance, low cost. PMID- 4219143 TI - Mechanism of the mutagenic activity of diazoacetylglycine derivatives. PMID- 4219144 TI - Problems peculiar to the diagnosis and management of asthma in children. PMID- 4219145 TI - [Contributions of parasitic immunology to hematology]. PMID- 4219146 TI - [Myelomatous paraproteinemia of the IgA or IgG type and blood lipids]. PMID- 4219147 TI - [Haptoglobin level, malaria and anemia in adult Africans]. PMID- 4219148 TI - [Contribution to the bacteriological study of Mycobacterium simiae, M. habana, M. asiaticum]. PMID- 4219149 TI - [The effect of ecdysterone on the molting of healthy crabs, Carcinus mediterraneus, and those parasitized by Sacculina carcini]. PMID- 4219151 TI - [Transmembrane potentials in the protozoan parasite Gregarina blaberea]. PMID- 4219152 TI - [The absorption of glucides during the digestion of corn starch in pigs]. PMID- 4219150 TI - [Ultrastructural aspects of the integumentary histoblast areas of the abdomen of Calliphora erythrocephala during the first larval stage]. PMID- 4219153 TI - [A comparative study of the neurons of the superior cervical ganglion of the rat maintained in culture with or without subsequent transplantation]. PMID- 4219154 TI - [Genetic analysis of a thelygenic line of Idotea balthica stagnea Tinturier Hamelin (Isopoda valvifera). Linkage between sexual inversion and pigmentary phenotype]. PMID- 4219155 TI - [The comparison between the number of oocytes per ovary and the number of egg layings in the migratory cricket Locusta migratoria capito (Sauss.) in nature]. PMID- 4219156 TI - [Eventual role of respiratory proteins in the resistance to cold of certain invertebrates]. PMID- 4219158 TI - [A method of measuring the total level of biological activity of activated sludge in water purification plants]. PMID- 4219157 TI - [The total alkaloids of Fumaria parviflora contain N-methylhydrastine and N methylhydrasteine]. PMID- 4219159 TI - [Degradation of cellulose by a soil microorganism: Sporocytophaga myxococcoides. Characterization of an exoglucanase]. PMID- 4219160 TI - [Study of a new class of mutants of Escherichia coli tolerant to colicins D and E3]. PMID- 4219161 TI - [The bactericidal properties of seawater]. PMID- 4219162 TI - [Antigenicity of a soluble antigen (glycoprotein) of purified rables virus, treated with Triton X 100]. PMID- 4219163 TI - [Effect of various drugs on the distribution of the liquid volume of an erythrocyte suspension]. PMID- 4219164 TI - [Modifications by acetylcholine of adenyl cyclase activity of a subcellular fraction and of acetylcholinesterase from Electrophorus electricus (L.)]. PMID- 4219165 TI - [Functional characteristics of the visual field receptors of the anterior dorsolateral nucleus in the pigeon]. PMID- 4219166 TI - [Variation of serum gonadotropins and progesterone during hyperprolactinemia induced by sulpiride (Dogmatil) during the luteal phasis of the menstrual cycle]. PMID- 4219167 TI - [Variation of the content of antidiuretic hormone in the pituitary in the newborn rabbit]. PMID- 4219168 TI - [Protein nutrition of the chimpanzee in its natural forest environment]. PMID- 4219169 TI - [Demonstration of actinomysin D luminescence]. PMID- 4219170 TI - [Purification of lipoprotein lipase from human adipose tissue by affinity chromatography]. PMID- 4219171 TI - [Characterization of a new calcium metalloprotein from crustacean myogen]. PMID- 4219172 TI - [Research on the X antigen responsible for the production of anti-Salmonella typhi antibodies, protectors for the chick embryo]. PMID- 4219173 TI - [Prolongation of the survival duration of cutaneous allograft in the rat by injections of a soluble extract from the donor's liver]. PMID- 4219174 TI - [Fetoplacental lesions following administration of high doses of ergocalciferol (vitamin D2) to the pregnant rat]. PMID- 4219175 TI - [Cordycepine and the specific uterine protein fraction induced by estradiol]. PMID- 4219176 TI - [Constant presence in wines of erythritol, arabitol and mannitol]. PMID- 4219177 TI - [Lethality syndrome and expression during ontogenesis of the lethal mitotic mutationlm, in the urodele Pleurodeles waltlii Michah]. PMID- 4219178 TI - [Trisomy and fertility in a female of Pleurodeles waltlii Michah. (Amphibian, Urodele). Analysis of the descendance]. PMID- 4219179 TI - [In vitro demonstration of drug desensitization of the acetylcholine receptor with fragments of excitable membrane from the torpedo fish]. PMID- 4219180 TI - [Suppression of the spasmogenic action of scorpion venom isolated guinea pig ileum by an inhibitor of membrane permeability to calcium]. PMID- 4219181 TI - [Comparative antitumoral cytostatic effect of splenic or peritoneal cells of mice with teratocarcinoma or immunized with tumoral cells. Stimulating effect of BCG and cyclophosphamide]. PMID- 4219182 TI - [Post-traumatic ossification (clinical and therapeutic considerations.)]. PMID- 4219183 TI - Cellular changes in intrauterine malnutrition. PMID- 4219184 TI - Biochemical markers of intrauterine malnutrition. PMID- 4219185 TI - Nitrogen balance during pregnancy. PMID- 4219186 TI - Chorionic gonadotropin synthesized in cultivated trophoblast. PMID- 4219188 TI - Crystals in hyperfunctioning rat parathyroid cells. PMID- 4219187 TI - Chemical and immunological properties of iodocompounds associated with particulate fractions of hog thyroid cells. PMID- 4219189 TI - The effects of hyperthermia on pregnancy and prenatal development. PMID- 4219190 TI - [Effect of cholinergic substances on short-term memory and the level of excitability of the structures of the hippocampal gyrus]. PMID- 4219191 TI - [Effect of dihydroergotoxin and phentolamine on the alpha--adrenoreceptors of the vessels of the kidney and intestines]. PMID- 4219192 TI - [Structure and antitubercular activity of some diphenyl esters]. PMID- 4219193 TI - Histopathological studies on liver tumorigenesis in rats treated with polychlorinated biphenyls. PMID- 4219194 TI - [Measurement of intrahepatic pressure as an index of portal pressure]. PMID- 4219195 TI - [Weil's disease. Report of a case]. PMID- 4219196 TI - [Schistosomiasis mansoni. Clinical manifestations observed in ambulatory patients of rural Venezuela]. PMID- 4219197 TI - [Endoscopic findings in various nephropathics]. PMID- 4219198 TI - [Schultz' autogenous training of groups of patients with digestive functional disorders. experience in 100 outpatients. Results]. PMID- 4219199 TI - [Hemorrhagic gastritis. analysis of 3 cases treated with sodium bicarbonate persusion]. PMID- 4219200 TI - [Pancreato-cholangiography using duodenoscope]. PMID- 4219201 TI - [The role of deoxyribonuclease in the treatment of chronic lymphocytic leukemia]. PMID- 4219202 TI - [Cytosine arabinoside in the treatment of leukemic meningitis]. PMID- 4219203 TI - [The absolute lymphocyte count in Hodgkin's disease as an aid in survival prognosis]. PMID- 4219204 TI - Long-term cultures of leukocytes from leukemia and related disorders: methods and applications. PMID- 4219205 TI - [Cytoautoradiographic studies on immature cells in chronic myeloid leukemia and myelofibrosis]. PMID- 4219206 TI - [Essential thrombocytemia, Hematological, clinical and dynamic aspects in 5 cases]. PMID- 4219207 TI - [The leukocyte migration test: possibilities of its use]. PMID- 4219208 TI - [Electrophoretic variations of soluble proteins and various cellular enzymes of spleen and thymus glands in rats maintained on protein poor, hyperlipidic diets with and without choline]. PMID- 4219209 TI - [Tuberculous meningitis during the course of malignant lymphogranuloma. Study of 4 cases]. PMID- 4219211 TI - The X chromosome and the eye. The implications of recent microbiological models for clinical ophthalmology. PMID- 4219212 TI - Melanizing activity of blood & semen of rabbits of different coat colours. PMID- 4219210 TI - [New pathogenetic aspects of platelet pathology in childhood]. PMID- 4219213 TI - [Neuromuscular and skeletal adaptations to altered orofacial function]. PMID- 4219215 TI - Immunoglobulin class of antibodies in monkeys infected with Toxocara canis. PMID- 4219214 TI - Comparative infectivity for cattle of stabilates of Theileria lawrencei (Serengeti) derived from adult and nymphal ticks. PMID- 4219216 TI - Salmonella para A cultured from S. mansoni surgically recovered from man. PMID- 4219217 TI - [Study of isoniazid incorporation into Mycobacterium tuberculosis cells by means of electron microscopic autoradiography]. PMID- 4219218 TI - Proteolytic activity of Pseudomonas aeruginosa on neopeptone agar medium. PMID- 4219219 TI - Defense mechanisms in the mouth and their possible role in the prevention of dental caries: a review. AB - The mouth harbors organisms in great abundance; yet their variety is limited and it is noteworthy that some species present in the mouth are not found elsewhere. There are many antibacterial substances in the mouth, some of which may contribute to the control of the microbial flora in the mouth. The activity of some is enhanced in the presence of specific antibody, e.g. lactoferrin, although others appear unaffected, e.g. lactoperoxidase. Opinions differ as to whether the level of immunoglobulins in human saliva can be related to caries. Although it has been established in principle that caries can be prevented in animals by means of vaccination, substantial work remains to be done before a vaccine will be available for testing in humans. PMID- 4219220 TI - Keratin-filled pseudocysts of ducts of sebaceous glands in the vermilion border of the lip. AB - Pathologic changes of free sebaceous glands are rare compared to those of the skin. Two keratin-filled pseudocysts which developed in the excretory ducts of sebaceous glands in the vermilion border of the lower lip in an 86-year-old woman are described. The entity is probably related to milia of the skin. PMID- 4219221 TI - Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs. PMID- 4219222 TI - [Prediction of cerebrovascular accidents in hypertensive patients under a long term care multivariate regression analysis of risk factors]. PMID- 4219223 TI - [Traumatic encephalopathy and working ability]. PMID- 4219224 TI - [Subthreshold reactions to transmembranal polarization and intracellular registration of the potentials on the neuronal membrane]. PMID- 4219225 TI - Report on long term treatments with Sintisone (prednisolone-stearoylglycolate). PMID- 4219226 TI - Anesthesiologic considerations in psychiatric convulsive therapy. PMID- 4219228 TI - Factors in the health care system undergoing change. PMID- 4219227 TI - The site of size constancy. PMID- 4219229 TI - Whither virology? Trends and prospects in medical research. PMID- 4219230 TI - Viral hepatitis and hepatitis B antigen: recent advances. PMID- 4219231 TI - [ Gene frequencies in 17 polymorphism systems. Study on a sample of subjects living in the Paris region]. PMID- 4219232 TI - [ Monoclonal paraproteins in blood donors on Cap Finistere]. PMID- 4219233 TI - [The listeria infection]. PMID- 4219234 TI - Directional, reversible currents of blood flow in spinal cord arteries. PMID- 4219235 TI - [Structural features of the genomes of higher organisms]. PMID- 4219236 TI - [Characteristics of X-chromosome puffs in female Drosophila melanogaster]. PMID- 4219238 TI - [The ultrastructure of Dileptus anser infusoria micronuclei during interphase and mitosis]. PMID- 4219237 TI - [A cytofluorimetric approach to analysis of lipoprotein complexes in the cell]. PMID- 4219240 TI - [Nodal forms of mucormycoses in young cattle]. PMID- 4219239 TI - [Bentonite in the prevention and treatment of diarrheas in newborn calves]. PMID- 4219241 TI - [Determination of substances with gonadotropin inhibitory effect in the urine of anestral sheep]. PMID- 4219242 TI - [Effect of late sanguination and evisceration of slaughter rabbits on the quality of their meat]. PMID- 4219243 TI - [Estrogens in the blood of pregnant sheep after induction of estrus using medroxyprogesterone]. PMID- 4219245 TI - Violamycin, a new red-pigment antibiotic. PMID- 4219246 TI - [Comparison of biological activity of C- and N-Mannich bases, with and without nitrogen-mustard groups, in microbiological and animal-experiment screening systems in the search of new antineoplastic agents]. PMID- 4219247 TI - [Principles and possibilities of gene amplification in bacteria]. PMID- 4219248 TI - [Age-dependent distribution of penicillin V in rats]. PMID- 4219250 TI - Occurrence and activity of ureolytic bacilli in soils. PMID- 4219249 TI - [The clinical significance of urinary hydroxyproline determinations (author's transl)]. PMID- 4219251 TI - The cytopyge of ciliata. IV An experimental study of the ingestion, digestion and defaecation in Oxytricha fallax. PMID- 4219252 TI - [Monolayers of kidney cells from Bufo marinus and study of its behaviour in vitro (author's transl)]. PMID- 4219253 TI - Stability of 131I-thyroxine and of 131-Itri-iodothyronine: the influence of radiolytic disintegration of certain diagnostic tests. PMID- 4219254 TI - [Experiences with the effective Thyroxine Ratio (ETR) test]. PMID- 4219255 TI - Irradiation of small structures through the intact skull. AB - The physical conditions for producing minute disc-shaped lesions for functional radiation surgery by means of narrow beam irradiation are discussed. The intention was a treatment procedure for routine clinical use and with high physical and mechanical reproducibility. The possibilities of using high energy electrons, supervoltage roentgen radiation, gamma emitting nuclides or fast neutrons in a technique for routine clinical use were investigated. The radiation of choice taking physical properties, radiation biologic factors and practical circumstances into account was considered to be 60-Co gamma radiation. A treatment apparatus containing 179 60-Co sources within a spherical sector of 70 degrees latitude and 160 degrees longitude was constructed. PMID- 4219256 TI - [Recent pharmacologic aspects of sulfamides modifying insulin secretion (hypoglycemic and hyperglycemic sulfamides)]. PMID- 4219257 TI - [Growth hormone secretion in man]. PMID- 4219258 TI - Geriatric nursing practice. Relying on nurses to improve nursing homes. No. G-94. PMID- 4219259 TI - [Long-term cortisone therapy and hazards of anesthesia]. PMID- 4219260 TI - [Intensive care in acute stroke]. PMID- 4219261 TI - Effects of chemicals on light-induced responses in the isolated carp retina. PMID- 4219262 TI - Enzymes that repair or edit ultraviolet-irradiated DNA. PMID- 4219263 TI - DNA repair in Bacillus subtilis: comparative studies with gamma-rays and ultraviolet light. PMID- 4219264 TI - Origin and development of life in relation to solar energy. PMID- 4219265 TI - Immunological cross reactions among strains of Hydrogenomonas, Pseudomonas and Alcaligenes. PMID- 4219266 TI - Presence of growth factors for Methanobacterium ruminantium in both gram-positive and gram-negative bacteria. PMID- 4219268 TI - [Recent acquisitions on the behavior of macrophages in the acquired immunity against tuberculosis]. PMID- 4219267 TI - Localization and phenotypic expression of a Tol marker in Citrobacter freundii. PMID- 4219270 TI - [Possibility of resensitization of resistant Mycobacterium tuberculosis strains]. PMID- 4219269 TI - [Morphological aspects of the infection and re-infection with M.t. (Mycobacterium tuberculosis) resistant to chemo-antibiotics]. PMID- 4219271 TI - [Behavior of drug-resistant mutants of the H37 Rv tubercular strain in experimental tuberculosis of the guinea pig]. PMID- 4219273 TI - The radioprotective effect of dimethyl sulfoxide on Bacillus subtilis cultures. PMID- 4219272 TI - [Effect of long-term application of SUISYNCHRON-premix on swine]. AB - Two groups of five female store pigs, weighing an average of 60 kg at the start of the experiment, were given either 1 or 10 mg metallibure zinc complex (SUISYNCHRON) per kg body weight once daily for six months, in the form of a 2% talcum premix added to concentrates. Clinical inspection, weight gain, haematological findings, blood sugar, serum transaminases, properties of urine and faeces, carcass examination and histological study (internal organs, endocrine glands, skeletal muscle) showed that the 1 mg/kg dosage had no toxic effect. The 10 mg/kg dosage resulted in considerable depression in appetite and some apathy in the pigs, but there was no evidence of a toxic effect. PMID- 4219274 TI - Translation of rabbit haemoglobin mRNA in oocytes of the Queensland cane toad, Bufo marinus. PMID- 4219275 TI - The nature of quantitative genetic variation in drosophila. II. Average dominance of abdominal bristle polygenes. PMID- 4219276 TI - A re-evaluation of energy-independent calcium-ion binding by rat liver mitochondria. AB - The impermeability of the mitochondrial inner membrane to the chelator ethanedioxybis(ethylamine)tetra-acetic acid permits discrimination between Ca(2+) which has been transported to the internal (matrix) phase and Ca(2+) which binds to the external surfaces of the mitochondrion. With this technique, it is shown that ;energy-independent high-affinity' binding is a measure of carrier-mediated active Ca(2+) transport in respiration-inhibited mitochondria; the carrier also transports Ca(2+) to the internal phase after treatment with carbonyl cyanide m chlorophenylhydrazone, but in this case the active-transport component is inhibited. The Ca(2+)-binding sites associated with the external membrane surfaces are similar in concentration and affinity for both inhibited and uncoupled mitochondria; it was not possible to measure external Ca(2+) binding which could be identified as carrier specific. The results are discussed in relation to the mechanism of mitochondrial Ca(2+) transport, and to previous studies of energy-independent Ca(2+) binding. PMID- 4219277 TI - Metabolic adaptations during lactogenesis. Lactose synthesis in rabbit mammary tissue during pregnancy and lactation. PMID- 4219278 TI - Separation, purification and properties of beta-lactamase I and beta-lactamase II from Bacillus cereus 569/H/9. AB - 1. A procedure was devised which is suitable for the isolation of beta-lactamase I and beta-lactamase II from Bacillus cereus 569/H/9 on a large scale. After adsorption on to Celite both enzymes were eluted in good yield and separated by chromatography on Sephadex CM-50. 2. beta-Lactamase I was separated into three main components by isoelectric focusing and into two components by chromatography. 3. The Zn(2+)-requiring beta-lactamase II obtained by this procedure had a lower molecular weight (22000) than beta-lactamase I (28000) and also differed from the latter in containing one cysteine residue. 4. The beta lactamase II contained no carbohydrate, but showed the thermostability of the enzyme isolated earlier as a protein-carbohydrate complex. 5. Amino acid analyses and tryptic-digest ;maps' indicate that some degree of homology between beta lactamase I and beta-lactamase II is possible, but that beta-lactamase I is not composed of the entire sequence of beta-lactamase II together with an additional peptide fragment. 6. A 6-methylpenicillin and a 7-methylcephalosporin showed much lower affinities for both enzymes than did penicillins and cephalosporins themselves. PMID- 4219279 TI - Metal cofactor requirements of beta-lactamase II. AB - 1. The apoenzyme obtained on removal of Zn(2+) from beta-lactamase II from Bacillus cereus 569/H/9 showed less than 0.001% of the activity of the Zn(2+) containing enzyme. 2. Removal of Zn(2+) led to a conformational change in the enzyme and partial unmasking of a thiol group. 3. Replacement of Zn(2+) by Co(2+), Cd(2+), Mn(2+) or Hg(2+) gave enzymes with significant, but lower, beta lactamase activity. No activity was detected in the presence of Cu(2+), Ni(2+), Mg(2+) or Ca(2+). 4. Equilibrium dialysis indicated that the enzyme had at least two Zn(2+) binding sites. With benzylpenicillin as substrate the variation in activity with concentration of Zn(2+) indicated that activity paralleled binding of Zn(2+) to the site of highest affinity. 5. Replacement of Zn(2+) by Co(2+) and Cd(2+) gave enzymes with absorption bands at 340 and 245nm respectively, and raised the question of whether the thiol group in the enzyme is a metal-ion ligand. 6. Reduction of the product obtained by reaction of denatured beta lactamase II with Ellman's reagent [5,5'-dithiobis-(2-nitrobenzoic acid)] gave a protein which could refold to produce beta-lactamase II activity in high yield. PMID- 4219280 TI - The macromolecular properties of blood-group-specific glycoproteins. Characterization of a series of fractions obtained by solvent fractionation. AB - 1. The glycoprotein components of a human ovarian-cyst fluid were isolated by a solvent [95% (w/w) phenol]-extraction procedure; the phenol-insoluble water soluble glycoprotein was further fractionated by (NH(4))(2)SO(4) and by ethanol to yield eight fractions. 2. The fractions were analysed in terms of amino acids, fucose, galactose, N-acetylglucosamine, N-acetylgalactosamine and sialic acid. Variations occurred, particularly in the proportion of peptide; these were partly correlated with varying extent of serological activity. 3. The fractions were characterized physicochemically in terms of buoyant density and degree of spreading in a density gradient, sedimentation velocity and molecular weight; their partial specific volumes and specific refraction increments were also determined. 4. The fractions showed wide variations in their sedimentation velocity and density-gradient patterns, and gave evidence of pauci-dispersity in density. The fraction regarded as the most typical blood-group-specific glycoprotein sedimented as a single rapidly spreading peak and was of high molecular weight. 5. Significant correlations were observed between the physical properties of the glycoprotein fractions and the amount of their peptide component. The buoyant densities and sedimentation coefficients varied in a manner that suggested the existence of two families of glycoproteins. 6. It is suggested that variability in the extent of glycosylation, or in the degree of cross-linking, might account for the two families of glycoproteins, and that the extent of cross-linkage might also be a factor determining the solubility of these glycoproteins in hot saturated (NH(4))(2)SO(4). PMID- 4219281 TI - The amino acid sequence of the peptide containing the thiol group of creatine kinase from normal and dystrophic chicken breast muscle. Comparison of some of the immunological properties of the antibodies developed in rabbits against these enzymes. AB - The major (14)C-labelled peptides from creatine kinase from normal and dystrophic chicken muscle obtained by carboxymethylating the reactive thiol groups with iodo[2-(14)C]acetic acid and digestion with trypsin were purified by ion-exchange chromatography on Dowex-50 (X2) and by paper electrophoresis. The chromatographic characteristics of the (14)C-labelled peptides, their electrophoretic mobilities at pH6.5, and their amino acid compositions were identical for the two enzymes. The sequence of amino acids around the essential thiol groups of creatine kinase from normal and dystrophic chicken muscle was shown to be Ile-Leu-Thr-CmCys-Pro Ser-Asn-Leu-Gly-Thr-Gly-Leu-Arg (CmCys, carboxymethylcysteine). This sequence is almost identical with that for the creatine kinases in human and ox muscle and bovine brain and is very similar to that of arginine kinase from lobster muscle. Antibodies to the enzymes were raised in rabbits and their reaction with the creatine kinase from normal and dystrophic muscles in interfacial, immunodiffusion and immunoelectrophoretic experiments was studied. The cross reaction between normal muscle creatine kinase and antisera against the dystrophic muscle enzyme (or vice versa) observed by immunodiffusion and by immunoelectrophoretic experiments further suggests that the enzymes from normal and dystrophic chicken muscle are similar in structure. The results of the present study, the identical amino acid sequence of the peptides containing the reactive thiol group from both the normal and dystrophic chicken muscle enzymes and the immunological similarities of the two enzymes are in accord with the similarity of the two enzymes observed by Roy et al. (1970). PMID- 4219282 TI - Polyribosomal and particulate distribution of lysyl- and phenylalanyl-transfer ribonucleic acid synthetases. AB - 1. Only two aminoacyl-tRNA synthetases from Chinese hamster ovary cells are found associated with ribosomes and polyribosomes. 2. Phenylalanyl-tRNA synthetase activity is found with the 60S subunit, 80S monoribosome and individual polyribosomes. An additional 15S form of the enzyme is also seen. 3. Lysyl-tRNA synthetase activity is found in a form of about 20S and associated with ribosomal subunits and polyribosomes. The ribosomal subunits having lysyl-tRNA synthetase activity are about 6S larger than the bulk of the ribosomal subunits. 4. The lysyl- and phenylalanyl-tRNA synthetases found in different complexes have differential sensitivity to EDTA and centrifugation properties. PMID- 4219283 TI - The localization of a vitamin K-induced modification in an N-terminal fragment of human prothrombin. AB - 1. The N-terminal fragment (PF-I) split off from prothrombin during coagulation was purified to homogeneity from human serum. 2. The apparent molecular weight is 27000+/-2000 in sodium dodecyl sulphate-polyacrylamide-gel electrophoresis, whereas a value of about 19600 is obtained by calculation based on amino acid and carbohydrate analyses. The N-terminal sequence is an Ala-Asx bond. The fragment contains about 16% carbohydrate, binds phospholipids in the presence of Ca(2+) and is adsorbed to BaSO(4). The pK(a) of its BaSO(4)-binding group(s) is 3.1-3.5. 3. By CNBr cleavage of fragment PF-I two peptides (C-1 and C-2) were obtained with molecular weights of about 5900 (C-2) and 12400 (C-1) on the basis of amino acid and carbohydrate analyses. Only the smaller (N-terminal) peptide is adsorbed to BaSO(4) and, since the ability of the whole protein to bind to BaSO(4) is known to be absent in samples obtained from patients treated with vitamin K antagonists, this peptide probably contains the site of a modification to the structure of the protein which occurs during biosynthesis and depends on vitamin K. This peptide does not contain hexosamine or sialic acid. PMID- 4219285 TI - [Effect of spreading depression on the activity of penicillin foci in the cerebral cortex]. PMID- 4219284 TI - Preliminary characterization of Thy-1.1 and Ag-B antigens from rat tissues solubilized in detergents. AB - 1. A radioactive binding assay for Thy-1.1 alloantigen which functions in the presence of detergents was established by using glutaraldehyde-fixed thymocytes as target cells. Thy-1.1 activity in detergent extracts was then assayed by measuring inhibition of the binding assay. 2. Solubilization of Thy-1.1 from whole thymocytes, and their membranes by a large number of non-ionic detergents and deoxycholate was studied. In the same extracts Ag-B(4) histocompatibility antigenic activities were measured. With the exception of Nonidet P-40, the detergents did not affect the antigenicity of Thy-1.1, but only Lubrol-PX and deoxycholate gave effective solubilization as measured by activity remaining in the supernatant after centrifugation at 200000g for 40min. With Ag-B(4) antigen, Triton X-100, Triton X-67 and Nonidet P-40 gave effective solubilization as well as Lubrol-PX and deoxycholate. Solubilization of Thy-1.1 activity from leukaemia cells and a brain homogenate was also studied, but none of the non-ionic detergents gave satisfactory results with these tissues. 3. Extracts from thymocyte membranes were further examined by gel filtration and sucrose gradient centrifugation. The Thy-1.1 activity behaved as a single component in deoxycholate with a density similar to that of a globular protein, but in Lubrol PX the antigen was contained in a low-density complex. In Lubrol-PX extracts Ag B(4) was also found in aggregates not observed in deoxycholate. 4. The s(20,w) values for Thy-1.1 and Ag-B(4) antigens in deoxycholate were 2.4 and 4.4, and v values were 0.70 and 0.75 respectively. The Stokes radius observed for Thy-1.1 was 3.1nm and for Ag-B(4) 5.3nm. By using these values the molecular weights for the antigen-detergent complexes were calculated to be 28000 for Thy-1.1 and 100000 for Ag-B(4). PMID- 4219286 TI - [Ovarian adenocarcinomas: 5 year results of treatment of 157 cases irradiated at Fondation Curie (1956-1968)]. PMID- 4219287 TI - [Nutrition problems in Africa]. PMID- 4219288 TI - [Radioimmunologic detection of antigens of cancerous origin]. PMID- 4219289 TI - [Development of the sensitivity to antibiotics in tuberculous bacteria isolated in the urban milieu of C.H.U. in Dakar (1966-1973)]. PMID- 4219290 TI - [Serodiagnosis of toxoplasmosis by indirect immunofluorescence, complement fixation and its relationship with IgM anti-toxoplasma antibodies]. PMID- 4219292 TI - [The leischmaniases in Morocco]. PMID- 4219291 TI - [Antibiotic sensitivity of Gonococcus strains isolated at Butare, Rwanda]. PMID- 4219293 TI - [A study of Neisseria meningitidis isolated in the Republic of Mali in 1970]. PMID- 4219295 TI - Seroepidemiology of Congo virus (related to the virus of Crimean haemorrhagic fever) in Nigeria. AB - A survey for neutralizing antibodies to Congo virus was carried out in Nigeria. Of a total sample population of 250, comprising 141 males and 109 females, 9 males and 15 females had antibody levels >/= 1.5 log neutralization index. In the age group 0-10 years 4 of 84 males and 14 of 79 females had antibody levels >/= 1.5 log neutralization index. There was no evidence of nonspecific antiviral activity in the sera tested. PMID- 4219294 TI - An evaluation of an agar gel diffusion test with crude and purified antigens in the diagnosis of hydatid disease. AB - The sensitivity of the indirect haemagglutination test for the diagnosis of hydatid disease, although high, is insufficient. Agar gel diffusion tests for the diagnosis of this disease have not received much attention in the past and have been considered unsatisfactory. The authors propose such a test and evaluate its results in comparison with those of the indirect haemagglutination test. PMID- 4219296 TI - The ovicidal effect of selected chemicals against eggs of Echinococcus granulosus. AB - The ovicidal activity of various chemicals against eggs of E. granulosus was evaluated by measuring infectivity to CF(1) mice after exposing the eggs to aqueous solutions of the chemicals for 1 h at room temperature. Significant reductions in infectivity were observed in eggs treated with Lugol's iodine, 0.015% ammonium dodecylbenzenesulfonate, 70% ethanol, or 5% or 10% glutaraldehyde. No cysts developed in 10 mice that received doses of 1 000 eggs treated with 5% glutaraldehyde, and only 1 of 10 mice developed cysts after exposure to eggs treated with 10% glutaraldehyde. PMID- 4219297 TI - [Changes in the parathymic lymph nodes of the mouse after intraperitoneal injection of L forms of Streptococcus group A]. PMID- 4219298 TI - [A new metabolic disease: the complete deficit of adenine phosphoribosyltransferase and lithiasis of 2,8-dihydroxyadenine]. PMID- 4219299 TI - [Comparison of erucic and oleic acids oxidation by human heart mitochondria]. PMID- 4219301 TI - [Synthesis and biological activity of the 1-34 sequence of humen parathormone]. PMID- 4219300 TI - [Effect of progesterone on glycoprotein biosynthesis in prepubertal rabbit uterus polysomes]. PMID- 4219302 TI - [Preliminary study, by indirect method, of rat brain mitochondrial membrane permeability for anionic substrates]. PMID- 4219303 TI - [Effect of CO2 on unit activities of cells in layer V of Rexed of the dorsal horn of cat spinal cord]. PMID- 4219304 TI - [Electrophysiology of connections between baso-lateral amygdaloid nuclei and thalamic central median-parafascicular nuclei in the cat]. PMID- 4219305 TI - [Recurrent degradation by glycosidases from Canavalia ensiformis of the polysaccharidic bond of a glycoprotein isolated from human parotid saliva]. PMID- 4219306 TI - [Cardiovascular effect and toxicity of hydroxy-9-ellipticine in dogs]. PMID- 4219307 TI - [Comparison of reactivity and heterospecificity of normal and leukemic human cells towards animal anti-thymocyte serums. Cytotoxic activity]. PMID- 4219308 TI - [Double blind statistical study of therapeutic effect of a radioactivy yttrium (90Y) charged colloid on rheumatoid arthritis of the knee]. PMID- 4219309 TI - [Electron microscopic autoradiography of Ehrlich tumor cell nucleoli. Demonstration of DNA in fibrillary centers]. PMID- 4219310 TI - [Role of glycoproteins in chemotactic migration of chick germinal cells, results with concanavalin A in organ culture]. PMID- 4219312 TI - [Ultrastructural aspects of the cytoplasm of the female germinal cell in chick embryo]. PMID- 4219311 TI - [Role of vitamin A in cytochrome P-450 induction by DDT]. PMID- 4219313 TI - [Renewal of carp (Cyprinus carpio L.) intestinal epithelium. Seasonal influence]. PMID- 4219314 TI - [Lysosomal activity of rat supra-optic nucleus during the first hours following colchicine-induced intracellular retention of neurosecretions]. PMID- 4219315 TI - [Glycemic and food taking response to intra-auricular and portal injection of 2 desoxy-d-glucose in the rat]. PMID- 4219316 TI - [Incorporation of L-3-4-dihydroxyphenylalanine (L-Dopa) by various cells of chick embryo anterior pituitary]. PMID- 4219317 TI - [Trace-autoradiographic study of the proliferation of cultured nerve cells]. PMID- 4219318 TI - [Analgesia induced by stimulation of the cat central nucleus of the raphe]. PMID- 4219319 TI - [New rapid radioimmunologic method for estimation of plasma progesterone. Application to early diagnosis of gestation in the ewe and goat]. PMID- 4219320 TI - [Photoreduction of 2,6 dichlorophenol indophenol and ferricyanide by chloroplast fragments from Chlamydomonas]. PMID- 4219321 TI - [Stimulation of specific immunologic processes by a glycoprotein factor of bacterial origin]. PMID- 4219322 TI - [Thymidylate synthetase activity in the anterior pituitary of the male rat during growth and after castration]. PMID- 4219323 TI - [Effect of DDT pretreatment of young ducks on eventual reaction towards a peanut oil-cake by aspergillus flavus]. PMID- 4219324 TI - [Demonstration of recessive transmission in Willebrands diseases. Detection of heterozygotes]. PMID- 4219325 TI - [7, 12-Dimethylbenz(a)anthracene (DMBA) metabolism by rabbit liver homogenates]. PMID- 4219326 TI - [Sensitivity of embryonic mouse testis to luteinizing hormone, LH]. PMID- 4219327 TI - [Inhibition by methadone of central vagus nerve stimulation of pancreas provoked by 2-desoxy-D-glucose. Desensitization by repeated administration]. PMID- 4219328 TI - [Exchange of information between T and B cells for synthesis of specific antibodies in vivo]. PMID- 4219329 TI - [Action of chloral hydrate on human lymphocyte mitosis in culture stimulated by phytohemagglutinin. Ultrastructural study]. PMID- 4219330 TI - [Immunofluorescence demonstration and distribution of somatostatin (SRIF) in the median eminence of vertebrates (mammals, birds, amphibia, fishes)]. PMID- 4219331 TI - [Trans-N-deoxyribosylase. Demonstration of a purine nucleoside: purine deoxyribosyl transferase in Lactobacillul]. PMID- 4219332 TI - [Study of a new synthetic antibacterial agent: 8-ethyl-5-oxo-2-piperaziny 5,8 dihydro-(2,3-d)pyrimidine-6-carboxylic acid (pipemidic acid)]. PMID- 4219333 TI - [Effect of fenfluramine on the mechanisms of transport of brain serotonin in rat synaptosomes]. PMID- 4219334 TI - [Description of 12 bacteriophages isolated from Bacillus thuringiensis]. PMID- 4219335 TI - [Application of liquid phase electrophoresis to the study of phosphate groups in human platelets blocked by pralidoxime]. PMID- 4219336 TI - [Comparison of lethal effects induced by 645 Mev helions and gamma rays on cancer cells or mice]. PMID- 4219338 TI - [Cytologic effects of trimethoprim on cultured fibroblasts]. PMID- 4219337 TI - [Influence of several nitrogen heterocycles on the survival of mice submitted to lethal doses of gamma rays]. PMID- 4219339 TI - [Some constituents of rabbit colic juice]. PMID- 4219340 TI - [Subcellular location of plutonium citrate (239Pu) in rate hepatocytes]. PMID- 4219341 TI - [Selective neuromuscular block in extrafusal junctions of skeleto-fusimotor axons produced by high frequency repetitive stimulation]. PMID- 4219342 TI - [Development of aldosteronemia of fetus and newborn guinea pig during the perinatal period]. PMID- 4219343 TI - [Calcium uptake by horse parathyroid gland]. PMID- 4219344 TI - [Influence of diet, cortisone and insulin on variations in enzyme activity of pyruvate carboxylase (EC 6.4.1.1) and phosphoenolypyruvate carboxykinase (EC 4.1.1.32) in rat liver]. PMID- 4219345 TI - [Hemolytic activity of diacidic phospholipids]. PMID- 4219346 TI - [Extracellular leucine aminopeptidases (EC 3.4.1.1) of Aspergillus oryzae (IP 410). Glycoprotein nature of the fraction leucine aminopeptidase 1]. PMID- 4219347 TI - [Gas chromatographic determination of specific radioactivity of estrogens]. PMID- 4219348 TI - [Bacteriocin production and lysogeny in Shigella of subgroup A]. PMID- 4219349 TI - [Characterization and classification of Proteus esterases]. PMID- 4219350 TI - [Effect of actinomycin D on virus production in a cell line chronically infected by a murine oncornavirus]. PMID- 4219351 TI - [Phenotype of an E coli K 12 mutant resistant to thymine deficiency death]. PMID- 4219352 TI - [New preparations of and indications for long acting nitrate derivatives]. PMID- 4219353 TI - [Characteristics of growth and sensitivity to cytostatics of Walker 256 carcinosarcoma in randombred and Wistar rats]. PMID- 4219354 TI - [Effect of administration of synthetic TRH in patients with endemic goiter]. PMID- 4219355 TI - [The TRH stimulation test in hyperthyroid patients following prolonged therapy with thiocarbamides]. PMID- 4219356 TI - [Changes in the TSH and thyroxine level in the serum of obese subjects following administration of TRH]. PMID- 4219357 TI - Antitumor activity of cell-wall skeletons and peptidoglycolipids of mycobacteria and related microorganisms in mice and rabbits. PMID- 4219358 TI - [Bilirubin level in the amniotic fluid as an indicator in the management of the delivery in RH sensitized pregnancy]. PMID- 4219359 TI - Organophosphorus poisoning. PMID- 4219360 TI - [Diagnosis, epidemiology and prophylaxis of equine infectious anaemia (author's transl)]. PMID- 4219361 TI - Some genetic interrelationships in England and Wales. A methodological investigation. PMID- 4219364 TI - [The significance of carbohydrates in parenteral feeding]. PMID- 4219362 TI - [Intravenous feeding in intensive care units]. PMID- 4219367 TI - [Principles of postoperative parenteral substitution using amino acid solutions]. PMID- 4219371 TI - [Infusion solutions-a principal cost factor for the hospital pharmacy]. PMID- 4219370 TI - [The significance of lipid metabolism in surgical disorders]. PMID- 4219372 TI - [Biochemical considerations of the use of carbohydrates in parenteral feeding]. PMID- 4219373 TI - [Combined administration of differently compounded nutritive solutions in intensive care medicine]. PMID- 4219374 TI - [Possibilities and significance of the production of infusion solutions in hospital pharmacies]. PMID- 4219375 TI - [Fundamental principles of parenteral feeding in acute renal failure]. PMID- 4219376 TI - [Experimental studies on the efficacity of parenteral lipid administration]. PMID- 4219377 TI - [Theoretical bases of short-term parenteral feeding]. PMID- 4219378 TI - [Effect of amino acid supply on protein metabolism in elderly surgical orthopedic patients]. PMID- 4219379 TI - [Fats in parenteral feeding]. PMID- 4219380 TI - [Lipids in parenteral feeding]. PMID- 4219381 TI - [The utilization of fat emulsions in human parenteral feeding]. PMID- 4219383 TI - [Indications for parenteral administration of fats in surgical patients]. PMID- 4219382 TI - [Utilization of fat emulsions in the parenteral feeding of man]. PMID- 4219384 TI - [Indications for parenteral fat administration in surgery]. PMID- 4219385 TI - [Essential fatty acids in serum cholesterol esters before and after stomach surgery]. PMID- 4219386 TI - [Essential fatty acids in serum cholesterol esters prior to an following gastric surgery]. PMID- 4219387 TI - [Discussion on parenteral feeding]. PMID- 4219388 TI - [Behavior of lipids during parenteral administration of carbohydrates]. PMID- 4219389 TI - [The reaction of lipids to parenteral administration of carbohydrates]. PMID- 4219390 TI - [Mechanism of serum uric acid increase during continuous xylitol infusions]. PMID- 4219391 TI - [Studies of the mechanism of serum uric acid elevation during continuous infusion of xylitol]. PMID- 4219392 TI - [The metabolism of the splanchnic region under the influence of fructose]. PMID- 4219394 TI - [Undesirable metabolic effects following the administration of larger doses of fructose and sorbitol]. PMID- 4219393 TI - [Undesirable metabolic effects following the administration of higher doses of fructose and sorbitol]. PMID- 4219395 TI - [Glucose in parenteral feeding]. PMID- 4219397 TI - [Discussion on parenteral administration of dietary carbohydrates]. PMID- 4219396 TI - [Parenteral administration of sugar substitutes with special reference to diabetes mellitus]. PMID- 4219398 TI - [Nitrogen balance in parenteral administration of amino acid solutions]. PMID- 4219399 TI - [Stoichiometry and nutritional-physiological significance of amino acid infusion solutions]. PMID- 4219400 TI - [Amino acid requirements in adults under conditions of parenteral feeding]. PMID- 4219402 TI - Some epidemiologic studies of transfusion-associated hepatitis. PMID- 4219401 TI - [Clinical studies of routine infusion therapy with 1.5% amino acid solutions in surgical medicine]. PMID- 4219403 TI - Circadian rhythm in Bence-Jones protein excretion by LOU rats bearing a transplantable immunocytoma, responsive to adrimycin treatment. PMID- 4219404 TI - [Three new ergot alkaloids from saprophytic culture of Claviceps paspali Stevens et Hall]. PMID- 4219405 TI - [Etiology of diabetic microangiopathy]. PMID- 4219406 TI - A brief discussion of a model for improving the cost effectiveness of a token economy in a rehabilitation setting. PMID- 4219407 TI - [In-vivo dosimetry using thermoluminescence in patients treated with with high energy electron]. PMID- 4219408 TI - [Isolation and serotyping distribution of Pseudomonas aeruginosa from river water]. PMID- 4219409 TI - [Subphrenic abscess due to Peptostreptococcus]. PMID- 4219410 TI - Experimental endocarditis. PMID- 4219411 TI - [Clinical features and occurrence of communicable diseases overseas]. PMID- 4219412 TI - [Hospital infections - etiology and management. 1. The changes in hospital infections and problems in future]. PMID- 4219413 TI - [Hospital infections - etiology and management. 2. Staphylococcal infections]. PMID- 4219414 TI - [Hospital infections. 3. Pseudomonas aeruginosa infection]. PMID- 4219415 TI - [Hospital infections. 4. Urological technics and hospital infections]. PMID- 4219416 TI - [Hospital infections. 5. Status of hospital infections and practice of their prevention (1)]. PMID- 4219417 TI - [Hospital infections. 6. Status of hospital infections and practice of their prevention (2)]. PMID- 4219419 TI - [Mycoplasma pneumoniae infections in adult. (I). Diagnosis]. PMID- 4219418 TI - [Suggestion on management of hospital infections]. PMID- 4219420 TI - [Mycoplasma pneumoniae infections in adult. (II)]. PMID- 4219422 TI - [Mycoplasma infections in animals]. PMID- 4219421 TI - [Mycoplasma pneumoniae infections in children]. PMID- 4219423 TI - [Staphylococcal infections]. PMID- 4219424 TI - [Survival of Salmonella typhi in urban water system and coastal sea water]. PMID- 4219425 TI - [On the growth of Coxsackie B viruses in circumfusion organ culture (Rose) of the embryonic mouse heart]. PMID- 4219426 TI - [New screening method for group A Streptococcus by dextrose disk method]. PMID- 4219427 TI - Pseudomonas aeruginosa serotypes encountered in the American University Hospital (AUH), Beirut, Lebanon. PMID- 4219428 TI - Postnatal undernutrition and human brain development. PMID- 4219429 TI - [A case of Sjogren's syndrome associated with macroglobulinemia which responded excellently to chlorambucil]. PMID- 4219430 TI - Vasospasm and adrenergic innervation of circle of Willis. AB - Cerebral vasospasm following the rupture of intracranial aneurysm presents perplexing situation, i.e. prolonged vasospasm results in cerebral infarct and too early relief causes recurrence of the bleeding. To understand mechanism underlying the cerebral vasospasm, catecholamine-containing sympathetic nerve plexus was examined in the arterial walls of the circle of Willis using rat, cat, dog and monkey using Falck-Hillarp's fluorescence method. The distribution of fluorescing nerve plexus was found to be essentially the same in the examination of all species. The distribution of the fluorescing fibers decreases in the following order; proximal anterior cerebral, internal carotid, distal anterior or proximal middle cerebral, and distal middle cerebral artery. The origin of the nerve plexus accompanying the basal cerebral arteries and the relation to the experimental cerebral vasospasm was investigated as detailed as they could. PMID- 4219431 TI - Islet cell transplantation. PMID- 4219432 TI - End-stage diabetic nephropathy. Discussion: general topics and summation. PMID- 4219433 TI - [Cutaneous manifestations of Chagas' disease. IV. Histopathology]. PMID- 4219434 TI - [Immunochemistry of Bothrops venoms. I. Comparative analysis of the antigenic components of 6 species of venoms against their respective antivenins by use of double diffusion and immunoelectrophoresis technics in agar gel]. PMID- 4219435 TI - [Immunochemistry of Bothrops venoms. II. Comparative analysis of the common antigenic components of 6 species of Bothrops venoms]. PMID- 4219436 TI - [Recent research on Chagas' disease performed in the Republic of Argentina]. PMID- 4219437 TI - A computer-aided diagnostic system using a small desk-top computer-calculator. PMID- 4219438 TI - [Dynamics of the carbohydrate content in Anacystis nidulans and Microcystis aeruginosa in the process of culture growth]. PMID- 4219439 TI - [Some biological properties of the LPP-1 cyanophage strain]. PMID- 4219440 TI - [Comparative study of the pathomorphology of an experimental infection caused by various strains of Rickettsia prowazekii]. PMID- 4219441 TI - [Patterns of aflatoxin accumulation in the grain of wheat, rye and rice]. PMID- 4219442 TI - [Experience with using plant and microbial adjuvants for producing immune ascitic fluids in laboratory animals]. PMID- 4219443 TI - [Distribution, biological characteristics and the national economic importance of bacteria of the Bacillus subtilis-mesentericus group]. PMID- 4219445 TI - [Study of the tuberculostatic activity of some azomethines and isonicotinyl hydrazones in vitro]. PMID- 4219444 TI - [Study of the antitumor properties of Mycobacterium]. PMID- 4219446 TI - [Effect of some new antibiotics and combination preparations on Rickettsia prowazekii]. PMID- 4219447 TI - An accurate method for measuring immunodiffusion rings. PMID- 4219448 TI - Infusion of synthetic TRH in the diagnosis of thyroid and pituitary dysfunction. PMID- 4219449 TI - [Relation between blood groups, blood cholesterol and triglyceride levels in a population sample aged 41 to 65 (preliminary results)]. PMID- 4219450 TI - Comparison of short wave diathermy and pulsed electromagnetic energy in treatment of soft tissue injuries. PMID- 4219452 TI - Technique for the visualization of precipitation bands obtained by gel immunodiffusion reactions for hepatitis B antigen detection. PMID- 4219453 TI - [Pyocin typization of Pseudomonas aeruginosa]. PMID- 4219451 TI - [Case of appendicular diverticulosis]. PMID- 4219455 TI - Angina pectoris and nitroglycerin. PMID- 4219454 TI - Clinical evaluation of Morfolep. PMID- 4219457 TI - [Arthropods as disease vectors in relation to environmental changes]. PMID- 4219456 TI - [Modern anesthesia using the general anesthetic ketanest (vetalar) in small animal practice]. PMID- 4219458 TI - [Cytogenetic studies in children with visual disorders]. PMID- 4219459 TI - [Action of the vagus nerve on the carbonic anhydrase content of human gastric mucosa]. PMID- 4219460 TI - Split and extremely thin glomerular basement membranes in hereditary nephropathy (Alport's syndrome). PMID- 4219461 TI - Aorta valve replacement using autologous fascia lata transplants. Late morphological changes, an electron microscopic study. PMID- 4219462 TI - The mode of growth of experimental metastases in rabbit femora. PMID- 4219463 TI - Electron microscopy of thrombocytes in the orthotopic porcine liver homograft during the late rejection. (Phagocytosis of thrombocytes by Kupffer cells). PMID- 4219464 TI - Hypothalamic neurosecretory nuclei and nucleus habenularis of epithalamus in essential hypertension. PMID- 4219465 TI - Liver schistosomiasis and primary biliary cirrhosis. A clinico-pathological study. PMID- 4219467 TI - Laboratoty techniques in rabies: tissue culture methods. PMID- 4219466 TI - [Histamine-histaminase-histidine-decarboxylase-histaminopexy system in acute leukemias]. PMID- 4219468 TI - Laboratory techniques in rabies: the complement fixation test. PMID- 4219469 TI - Safety precautions in handling rabies virus. PMID- 4219471 TI - Passive haemagglutination test for rabies antibodies. PMID- 4219472 TI - Laboratory techniques in rabies: gel-diffusion techniques. PMID- 4219470 TI - Laboratory techniques in rabies: hamgglutination and hemagglutination-inhibition tests. PMID- 4219473 TI - Laboratory techniques in rabies: electron microscopy. PMID- 4219474 TI - Purification of rabies virus and isolation of its components. PMID- 4219475 TI - Aluminium phosphate method for rabies virus purification. PMID- 4219477 TI - Laboratory technics in rabies: general considerations in vaccine production. PMID- 4219476 TI - A radioimmune assay for rabies binding antibody. PMID- 4219478 TI - An assessment of laboratory techniques in the diagnosis and prevention of rabies and in rabies research. PMID- 4219479 TI - Laboratory technics in rabies: Semple-type vaccine. PMID- 4219480 TI - Laboratory techniques in rabies: Fermi-type vaccine. PMID- 4219481 TI - Laboratory techniques in rabies: phenolized, freeze-dried sheep brain vaccine. A. Method used in the USSR. PMID- 4219482 TI - Laboratory techniques in rabies: phenolized, freeze-dried sheep brain vaccine. B. Method used at the Pasteur Institute, Paris. PMID- 4219484 TI - Laboratory techniques in rabies: suckling mouse brain vaccine. PMID- 4219483 TI - Laboratory techniques in rabies: suckling rat brain vaccine. PMID- 4219485 TI - Laboratory techniques in rabies: suckling rabbit brain vaccine. PMID- 4219486 TI - Laboratory techniques in rabies: ultraviolet-light irradiation for inactivation of vaccines. PMID- 4219487 TI - Laboratory techniques in rabies: chicken-embryo vaccine. PMID- 4219488 TI - Laboratory techniques in rabies: duck-embryo vaccine. PMID- 4219489 TI - Laboratory techniques in rabies: vaccine for man prepared in human diploid cells. PMID- 4219490 TI - Laboratory techniques in rabies: tissue culture vaccines for animals. PMID- 4219491 TI - Laboratory techniques in rabies: general considerations in safety and potency testing. PMID- 4219492 TI - Laboratory techniques in rabies: Habel test for potency. PMID- 4219493 TI - Laboratory techniques in rabies: modified Habel test for potency. PMID- 4219494 TI - Laboratory techniques in rabies: the NIH test for potency. PMID- 4219495 TI - Laboratory techniques in rabies: guineapig potency test for chicken-embryo vaccine. PMID- 4219496 TI - Laboratory techniques in rabies: shipments of specimens, and techniques for preparation of animal tissues. PMID- 4219497 TI - Laboratory techniques in rabies: the antibody binding test for vaccine potency. PMID- 4219498 TI - Laboratory techniques in rabies: test for neuroallergenic activity. PMID- 4219499 TI - Production of antirabies serum of animal origin. PMID- 4219500 TI - Preparation of antirabies immunoglobulin of animal origin: method used in the USSR. PMID- 4219501 TI - Preparation of antirabies immunoglobulin of human origin. PMID- 4219502 TI - Quantitative assay and potency test of antirabies serum and immunoglobulin. PMID- 4219503 TI - Laboratory techniques in rabies: methods of calculation. PMID- 4219504 TI - A rapid method for fluorescein labelling of rabies antibodies. PMID- 4219505 TI - Laboratory techniques in rabies: cell monolayer plaque test. PMID- 4219507 TI - A rapid tissue culture test for determining rabies neutralizing antibody. PMID- 4219506 TI - Proposed safety tests for inactivated rabies vaccine prepared in cell cultures. PMID- 4219508 TI - The immunoperoxidase reaction for demonstration of rabies virus. PMID- 4219509 TI - Laboratory techniques in rabies: rapid microscopic examination for Negri bodies and preparation of specimens for biological test. PMID- 4219510 TI - Laboratory techniques in rabies: the fluorescent antibody test. PMID- 4219511 TI - Laboratory techniques in rabies: the mouse inoculation test. PMID- 4219512 TI - Laboratory techniques in rabies: the virus neutralization index test in mice. PMID- 4219513 TI - [Long-term treatment of chronic urinary tract infections with the combination drug trimethoprim-sulfamethoxazol (Eusaprim) in chronic patients]. PMID- 4219514 TI - [Various peculiarities in geriatic therapy from the viewpoint of the internal medicine specialist]. PMID- 4219515 TI - [Phenoloxidases. The achievements of and prospects for study]. PMID- 4219516 TI - [Specific immunologic reactivity in mycosis caused by Trichophyton mentagrophytes (clinico-experimental study)]. PMID- 4219517 TI - [Ampicillin in therapy of gonorrhea in men]. PMID- 4219518 TI - On the electrophoretical differentiation and classification of proteins. IV. Disc electrophoresis and isoelectrical focusing in polyacrylamid gels of proteins and enzymes from various species, varieties and hybird species of strawberries. [authors transl]. PMID- 4219520 TI - [Influence of varity and storage-temperature on the substances involved in the enzymatic colour-change of potatoe bulbs (author's transl)]. PMID- 4219519 TI - [Nitrosamines in foods. Contributions to analysis, decomposition and formation I. Determination methods for model experiments (author's transl)]. PMID- 4219521 TI - [Organization of nephrologic care in the GDR (German Democratic Republic)]. PMID- 4219522 TI - [Studies on the specificity of antisera against denaturated desoxyribonucleic acids]. PMID- 4219523 TI - Fixation with mercury salts. PMID- 4219524 TI - [Neutral fats and cholesterol in cryostat preparations]. PMID- 4219525 TI - [Chemical aspects of permanganate fixation[]. PMID- 4219526 TI - [Problems of fixation in immunohitochemistry]. PMID- 4219527 TI - [Simple and effective method to avoid unspecific staining in immunohistology]. PMID- 4219528 TI - [The influence of the osmolality on the ultrastructure of isolated mitochondria. (author's transl)]. PMID- 4219529 TI - [Effect of hunger and re-feeding on rat liver DNA and nucleolar dry weight]. PMID- 4219530 TI - [Radioactive labeling of mouse adrenal cortex for study of steroid sulfation in inner cortex zone]. PMID- 4219531 TI - [Cholesterol crystal formation and its prevention in cryostat-sections of nervous tissue]. PMID- 4219532 TI - [Acetylcholinesterase in normal and regenerating ciliated epithelium of lineus sanguineus rathke (nemertimi)]. PMID- 4219533 TI - [Panel on tissue preparation and fixation. Introduction]. PMID- 4219534 TI - [Electron microscopical and cytochemical studies of catalase and peroxidase in rat lacrimal glands]. PMID- 4219535 TI - [Jejunum as stomach replacement. histological and enzyme-histochemical data of iso- and aniso-peristaltic implanted jejunum pieces]. PMID- 4219536 TI - [Cytochemical identification of endocrine stomach cells and their relation to number of parietalc ells and H+-secretion in normal and pathological circumstances]. PMID- 4219537 TI - [Histochemical studies of gastric mucosa synthesis of mucous materials in uremia]. PMID- 4219538 TI - [Application of industrial dyes: their quality, usability, their brand names. 1. definition of dyes]. PMID- 4219539 TI - [Survival time of removed tissue]. PMID- 4219540 TI - [Purity and contamination of industrial dyes. interference in histological and histochemical staining]. PMID- 4219541 TI - [Tissue preparation and fixation. Influence of diurnal rhythm]. PMID- 4219542 TI - [Purification of dyes by recrystallization]. PMID- 4219543 TI - [Two simple but useful methods for the analysis of dyes: gel-filtration chromatography and solvent extraction]. PMID- 4219544 TI - [Problems of column and thin layer chromatographic purification of dyes, demonstrated with brilliant cresyl blue as an example]. PMID- 4219545 TI - [Problems of industriald dye manufacturing]. PMID- 4219546 TI - [Standardization of dyes. requirements, norms]. PMID- 4219547 TI - [Co-operation between action committee C6, dyes in medicine and biology, and dye manufacturers]. PMID- 4219548 TI - [Tissue preparation and fixation. Freeze drying and cryostat technic]. PMID- 4219549 TI - [Mechanism of fixation]. PMID- 4219550 TI - [Characterization of fluorescent dyes]. PMID- 4219551 TI - [Tissue fixation for histochemical potassium determination according to voigt]. PMID- 4219552 TI - [Fixation of catecholamines]. PMID- 4219553 TI - [Significance of osmolality for quality of fixation with 8 different aldehydes]. PMID- 4219555 TI - The importance and histopathology of hypothalamic changes in animals inoculated intracerebrally with Hogyes' fixed strain of rabies virus. PMID- 4219554 TI - [Osteopathies of the upper jaw]. PMID- 4219556 TI - The choriocapillaris. PMID- 4219557 TI - Submacular choroidal vascular pattern. Experimental fluorescein fundus angiographic studies. PMID- 4219558 TI - The long posterior ciliary arteries. An experimental study. PMID- 4219559 TI - [Energy and protein requirements of the patient after surgery]. PMID- 4219560 TI - [Parenteral feeding: indications and practical aspects]. PMID- 4219561 TI - [Nutritional problems characteristic of patients with acute renal failure]. PMID- 4219562 TI - [Failures, risks and complications of parenteral hyperalimentation in digestive surgery]. PMID- 4219563 TI - [Prolonged parenteral feeding of infants]. PMID- 4219564 TI - Temperature-induced change in helicity of the inherently dissymmetrical disulfide group in cyclocystine. PMID- 4219565 TI - [Treatment of gas gangrene with hyperbaric oxygenation, parenteral hyperalimentation, antibiotic and heparin therapy and surgery. Apropos of 17 cases]. PMID- 4219566 TI - The problem of species variations. PMID- 4219567 TI - [Antibacterial activity in vitro of cyclacillin (author's transl)]. PMID- 4219569 TI - [Myocardial infarction and conduction disorders in the right bundle of His. Classification of histological lesions]. PMID- 4219568 TI - [Study of diastolic compliance, contractility and diastolic constraint of the left ventricle in obstructive myocardiopathy: inadequate myocardial hypertrophy]. PMID- 4219570 TI - [Ventricular aneurysms of posterior topography]. PMID- 4219571 TI - [Phonomechanography of recent myocardial infarction. The phonocardiogram]. PMID- 4219572 TI - [Phonomechanography in severe aortic insufficiency]. PMID- 4219573 TI - [Parietal ruptures of the heart in the acute stage of myocardial infarction: early diagnosis and current therapeutic approach]. PMID- 4219574 TI - [Experimental and critical study of procedures for myocardial revascularization]. PMID- 4219575 TI - [Complete atrio-ventricular block through section of the bundle of His secondary to closed theoracic trauma]. PMID- 4219576 TI - The value of serological techniques for the differentiation between Verticillum Albo-atrum Reink. & Berth. and V. dahliae Kleb. PMID- 4219577 TI - [Brazil). Isolation of microorganisms with significance in public health, from Sardinella aurita and Microdon ancylodon (author's transl)]. PMID- 4219578 TI - Serological studies on coffee rust. PMID- 4219579 TI - [Screening of irregular antibodies in pregnancy]. PMID- 4219580 TI - [Hemodynamic effects of nitroglycerin]. PMID- 4219581 TI - Identification of the structural gene for sucrase in Bacillus subtilis Marburg. PMID- 4219582 TI - Pleiotropic mutations affecting sporulation conditions and the syntheses of extracellular enzymes in Bacillus subtilis 168. PMID- 4219583 TI - The isozymes of phosphorylase kinase in various mammalian tissues. PMID- 4219584 TI - Cranial bony changes in ocular neurofibromatosis. PMID- 4219585 TI - A rare association of neurofibromatosis with Marfan's syndrome. PMID- 4219586 TI - Antibiotics and war injuries. PMID- 4219587 TI - In vitro studies linking induction of spontaneous antibody synthesis to an accessory cell with persisting antigen on its surface. PMID- 4219588 TI - A comparison of autoimmunity and experimental allergic thyroiditis in strain 2 and Hartley strain guinea pigs. PMID- 4219589 TI - Effects of pretreatment of mice with BCG cell walls in saline on subsequent vaccination with BCG oil droplet vaccine. PMID- 4219590 TI - Sterilization of Listeria monocytogenes by guinea pig peritoneal exudate cell cultures. PMID- 4219591 TI - Quantitative analysis of the 51Cr release cytotoxicity assay for cytotoxic lymphocytes. PMID- 4219592 TI - Exclusion of cooperating T cells as targets for heterologous anti-mu antiserum. PMID- 4219593 TI - Immunological memory in tuberculosis. I. Influence of persisting viable organisms. PMID- 4219594 TI - Immunosuppression of congenitally athymic (nude) mice with heterologous anti immunoglobulin heavy-chain antisera. PMID- 4219595 TI - Ontogeny of B lymphocytes. I. In vitro appearance of Ig-bearing lymphocytes. PMID- 4219596 TI - [Prevention of drepanocytic painful crises with hydergine]. PMID- 4219597 TI - [Comparative allergological study of Mycobacterium tuberculosis of the classical type and Mycobacterium tuberculosis var. Africanum (apropos of 400 intradermoreactions)]. PMID- 4219598 TI - Development of lymphocyte populations in the human foetal thymus and spleen. PMID- 4219599 TI - Monoclonal lymphocyte population in human plasma cell myeloma. PMID- 4219600 TI - B-cell markers on lymphoblasts in acute lymphoblastic leukaemia. PMID- 4219602 TI - [Neurocutaneous melanosis with chronic subdural hematoma on the left side and later on the right side--a case study]. PMID- 4219603 TI - Fine structural alterations in the developing spermatids of Musca domestica induced by the PCB, Aroclor 1254. PMID- 4219604 TI - [Pathoanatomic changes in experimental pneumonia caused by Pseudomonas aeruginosa]. PMID- 4219605 TI - Androgens in prenatal development: behavior changes in nonhuman primates and men. PMID- 4219606 TI - [Morphological and metric comparative study on the hand skeleton of recent primates III]. PMID- 4219607 TI - [Morphological and metric comparative study on the hand-skeleton of recent primates IV]. PMID- 4219608 TI - [Diverticulosis of the trachea and bronchi]. PMID- 4219609 TI - Thyrotropin releasing hormone induced thyrotropin release in euthyroid men. Effect of ethinyl oestradiol priming. PMID- 4219610 TI - [Balanced substitution therapy using infusion (electrolytes, amino acids, energy foods) in severe ill, injured patients]. PMID- 4219611 TI - Intravenous alimentation with a mixture of fat, carbohydrates and amino acids in small immature newborn infants--a preliminary report. PMID- 4219612 TI - [Lipid composition of a strains of bacteria in human dental plaque]. PMID- 4219613 TI - [Proceedings: Origin of increased patellar reflex in monkeys with partially transected spinal cords]. PMID- 4219614 TI - Proceedings: Neuron activities in prefrontal cortex during gazing behavior in monkeys. PMID- 4219615 TI - Proceedings: Prefrontal activities in monkeys inmaturely trained in delayed response task. PMID- 4219616 TI - Proceedings: Neuron activities in the posterior parietal association areas and visual orientation. PMID- 4219617 TI - [Proceedings: Nature of receptors receiving impulses from the muscle via afferent neurons]. PMID- 4219619 TI - Proceedings: Activities of motor cortex neurons during simple reaction time responses in monkeys. PMID- 4219618 TI - [Proceedings: Mode of response of a single cell to smell in the frontal lobe, piriform lobe, amygdaloid body, and olfactory bulb of the monkey]. PMID- 4219620 TI - [Proceedings: Effects of EDTA on mitochondrial respiration]. PMID- 4219622 TI - Proceedings: Plasma levels of luteinizing hormone during menstrual cycle and their response to gonadectomy in Japanese monkeys. PMID- 4219621 TI - [Proceedings: Cell division induction in the rat liver]. PMID- 4219623 TI - Editorial: Suppression of Rh-sensitisation by the use of anti-D immunoglobulin. PMID- 4219624 TI - Genetic code limit organisms--do they exist? PMID- 4219625 TI - Characterization of the primary structural homology between the 16s ribosomal RNAs of Escherichia coli and Bacillus megaterium by oligomer cataloging. PMID- 4219626 TI - [Study of blood proteins by the radial immunodiffusion method in patients with liver cirrhosis]. PMID- 4219628 TI - [Theory and methodology of planning production volumes]. PMID- 4219627 TI - [Screening for Listeria monocytogenes in placentas collected in the delivery room]. PMID- 4219629 TI - A comparison of betamethasone valerate aerosol and sodium cromoglycate in children with reversible airways obstruction. PMID- 4219630 TI - The effect of betamethasone valerate aerosol in exercise-induced asthma. PMID- 4219631 TI - [Comparative evaluation between the precipitation test, latex test, and the radial immunodiffusion test for determination of C-reactive protein]. PMID- 4219632 TI - [Determination of calcium in biological fluids. II. Complexometric determination of calcium in the urine]. PMID- 4219633 TI - [Complexometric determination of magnesium in the urine]. PMID- 4219634 TI - [Agarose gel electrophoresis and tube precipitin in the serological study of aspergillosis]. PMID- 4219635 TI - [Survival of lyophilized Lactobacillus acidophilus and Saccharomyces cerevisiae]. PMID- 4219636 TI - [Chagas' disease and trypanosomiasis rangeli in 3 ranchs of the Departmento Francisco Morazan, Honduras]. PMID- 4219638 TI - [Fixation of germ cells of the ovaries of sea shrimp for ultrastructural studies]. PMID- 4219637 TI - [Wild reservoirs and vectors of Trypanosoma cruzi. LVII=Natural infection of Phyllostomus hastatus hastatus (Tallas, 1767) by T. cruzi]. PMID- 4219640 TI - [Prenatal protein malnutrition and development of the nervous system]. PMID- 4219639 TI - [Changes in cerebral electrogenesis caused by vincamine in the baboon, Papio papio]. PMID- 4219641 TI - [Aspects of disseminated intravascular coagulation in the newborn]. PMID- 4219642 TI - [Hypercoagulation states in pediatric diseases]. PMID- 4219643 TI - [Disseminated intravascular coagulation syndrome in severe respiratory tract infections in infants]. PMID- 4219644 TI - [Various findings and working hypotheses concerning implications of the terrain in disseminated intravascular coagulation in children]. PMID- 4219645 TI - [The disseminated intravascular coagulation syndrome in severe enteral infections in infants]. PMID- 4219646 TI - [Tests for the rapid and early diagnosis of disseminated intravascular coagulation]. PMID- 4219647 TI - [Criteria for the use of heparin in consideration of the biological and clinical components of the disseminated intravascular coagulation syndrome]. PMID- 4219648 TI - [Combination of heparin and dipyridamol (persantin) in the treatment of various coagulation disorders in infants]. PMID- 4219649 TI - [Myocardial lesions in the course of interstitial pneumopathies in infants]. PMID- 4219650 TI - [Spontaneous immunorosette in acute lymphoblastic leukemia in children]. PMID- 4219651 TI - [Study of various ureteral malformations using fluorescence microscopy]. PMID- 4219652 TI - [Pneumocystis carinii pneumonia--a current problem]. PMID- 4219653 TI - [Treacher-Collins syndrome, with reference to a clinical case]. PMID- 4219654 TI - [Congenital mitral insufficiency (apropos of 3 clinical cases)]. PMID- 4219655 TI - [Centro-facial lentiginosis; study of 23 cases]. PMID- 4219657 TI - [Cleidocranial dysostosis]. PMID- 4219658 TI - [The role of genetic factors in the etiology of disseminated lupus erythematosus (DLE)]. PMID- 4219659 TI - [Rate of postnatal hemolysis in premature infants]. PMID- 4219656 TI - [Cerebral vascular malformations as etiological factors in epilepsy in children]. PMID- 4219660 TI - [Treatment of status asthmaticus in children]. PMID- 4219661 TI - [Our approach to the treatment of enuresis]. PMID- 4219662 TI - [Uses of ultramicroanalysis in the clinical laboratory. Note III. Determination of serum inorganic phosphorus and acid and alkaline phosphatases]. PMID- 4219663 TI - Haemodynamics in animals. PMID- 4219664 TI - Psychotherapy research in schizophrenia--another view of present reality. PMID- 4219665 TI - Patterns of psychiatric utilization by diagnosed schizophrenics in the Kansas City area. PMID- 4219666 TI - Studies on interaction of 4-nitroquinoline 1-oxide with RNA of hamster embryo cells. PMID- 4219667 TI - [Injuries of the ankle joint (author's transl)]. PMID- 4219668 TI - [Clinical experiments with intal nasal with patients suffering from rhinitis due to pollens (author's transl)]. PMID- 4219669 TI - [Interaction of vertebrate viruses and insect nuclear polyhedrosis viruses with transplantable diploid embryonal drosophila cells]. AB - When the Drosophila cells were infected with the mixo- and arboviruses, in case of influenza A/WSN virus a rise in the titre and slight cytopathogenic effect with the subsequent decrease in the titre was observed. Since the decrease in the virus titer was not observed when actinomycin D was added, it was supposed that interferonlike inhibitor may be produced by the infected cells. Vacuolization and increase in the size of the infected cells were caused by all the nuclear polyhedrosis viruses tested. The number of the infected cells depended on the virus type and multiplicity of the infection. PMID- 4219670 TI - [State of amino acid metabolism in patients with laryngeal cancer after laryngectomy and tube feeding]. PMID- 4219672 TI - [Culture media for isolation and quantitative determination of enterococci in dry milk]. PMID- 4219671 TI - [Lesion of the 8th cranial nerve pair in Recklinghausen's disease]. PMID- 4219673 TI - [Genetic studies on temperature-sensitive mutants of Lactobacillus casei phage J1 (author's transl)]. PMID- 4219674 TI - [The diagnostic possibilities of fibroduodenoscopy]. PMID- 4219675 TI - [Clinical application of a hypothalamic hormone stimulating thyrotropic secretion]. PMID- 4219677 TI - [Distribution of Golgi's cells in the cerebellar cortex of man, rhesus monkey and cat]. PMID- 4219676 TI - [A study of renal function using radioisotope methods in patients with diabetic nephropathy]. AB - An earlier and more manifested affect of glomerular function was established during the examination of 35 patients with diabetic nephropathy, 14 of them in a stage of renal insufficiency, with the help of radioisotope clearance methods (of EDTA, labelled with 169Yb for the determination of glomerular function and of hippuran, labelled with 131J for the determination of the renal plasma flow). The renal plasma flow is affected to a considerably more restricted extent. The combination of diabetic nephropathy with chronic pyelonephritis, found in 10 patients, does not affect substantially the mentioned functions of the kidney, but additional investigations were considered necessary in that field. Bilateral symmetric alterations are more frequently the secretory and excretory segmentsmthe establishment of unilateral alterations may speak of the presence of chronic pyelonephritis of uropathic character. The radioisotope methods, because of their accessibility and less possibilities for errors are recommended for renal functional investigations. PMID- 4219678 TI - [Biometric analysis of the number of neurons in the nucl. n. oculomotorii and nucl. n. trochlearis in an ontogenetic study on Tupaia belangeri]. PMID- 4219679 TI - [Changes due to age in the inner ear]. PMID- 4219680 TI - [Ligaments of the lateral meniscus in the monkey (Ceropithecus aetiops)]. PMID- 4219681 TI - Electron microscopic study of plasma cells in immunoproliferative diseases. Preliminary report. PMID- 4219683 TI - Problems of macromolecule ultrafiltration. PMID- 4219682 TI - [Diffuse juvenile papulotuberous xanthogranuloma]. PMID- 4219684 TI - Perspectives offered by enzyme binding in polymeric membranes. PMID- 4219685 TI - Extracapillary proliferative glomerulonephritis so-called malignant glomerulonephritis. PMID- 4219686 TI - Unilateral renovascular hypertension in the dog. PMID- 4219688 TI - Diuretics in chronic renal insufficiency. PMID- 4219687 TI - Pharmacology of diuretics: a progress report, 1968--1971. PMID- 4219689 TI - Diuretics in the treatment of arterial hypertension. PMID- 4219690 TI - Metabolic complications in the use of diuretics. PMID- 4219691 TI - Biochemical studies of the glomerular basement membrane in the diseased kidney. PMID- 4219692 TI - Trapping of urea and ammonia in the gut of uremic patients. PMID- 4219693 TI - Pathogenesis of the uremic state: a new perspective. PMID- 4219694 TI - Biochemical studies of the glomerular basement membrane in the normal kidney. PMID- 4219695 TI - The structural basis of glomerular filtration. PMID- 4219696 TI - Glomerular filtration of macromolecules. PMID- 4219698 TI - Artificial membranes. PMID- 4219697 TI - Role of anti-basement membrane immunity in human glomerulonephritis. PMID- 4219699 TI - Interface reactions between artificial membranes and blood. PMID- 4219700 TI - Cryoglobulinemia in glomerulonephritis exclusive of general diseases. PMID- 4219701 TI - Ultrastructural lesions of the glomerular basement membrane in hereditary chronic nephritis. PMID- 4219702 TI - Intravascular coagulation and nephropathies. PMID- 4219703 TI - Acute renal failure and intravascular coagulation. PMID- 4219704 TI - Renal disease and fibrinogen degradation products. PMID- 4219705 TI - Home dialysis in the United Kingdom: experience in a regional center. PMID- 4219706 TI - Maintenance home dialysis: four years' experience in Languedoc-Roussillon. PMID- 4219707 TI - One hundred patients on home dialysis. PMID- 4219708 TI - Drugs in the treatment of hyperuricemia. PMID- 4219709 TI - The Lesch-Nyhan syndrome. PMID- 4219710 TI - Hyperuricemia in children, with the exception of the Lesch-Nyhan syndrome. PMID- 4219711 TI - Recent data on uric acid lithiasis. PMID- 4219712 TI - Ureteral diverticulosis. A new case and a review of the literature. PMID- 4219713 TI - Ultrastructural concepts of drug metabolism. I. The hepatocyte: structure and function. PMID- 4219714 TI - Ultrastructural concepts of drug metabolism. II. The hepatocyte: phenobarbital and microsomal enzyme induction. PMID- 4219715 TI - A comprehensive approach to the treatment of drug dependence. PMID- 4219716 TI - Ultrastructural concepts of drug metabolism. III. The hepatocyte: membranes, lipids, and alcohol. PMID- 4219717 TI - [The technic of intrauterine fetal transfusion in cases of severe isoimmunization due to Rh-incompatibility]. PMID- 4219718 TI - [Description and experimental life cycle of Schellackia balli n. sp. (Lankesterellidae) a parasite of toads in Guyana (author's transl)]. PMID- 4219719 TI - [Homogeneity of the Filariae of batrachians, including the genus Waltonella, Ochoterenella and Madochotera; creation of Waltonellinae n. subfam (author's transl)]. PMID- 4219720 TI - [New arguments in favor of Actinocephalus thyropygi Rodgi and Ball 1961 being a Stenophora (Eugregarina Stenophoridae)]. PMID- 4219721 TI - [Lankesteria galliardi Garnham 1973]. PMID- 4219723 TI - Further studies on erythrocyte inorganic pyrophosphatase: an examination of different mammalian species and human-Chinese hamster hybrid cells. PMID- 4219722 TI - The detection and differentiation of the products of the human carbonic anhydrase loci, CAI and CAII using fluorogenic substrates. PMID- 4219724 TI - [The morphology of the Macacus rhesus and Macacus cynomolgus humerus (author's transl)]. PMID- 4219725 TI - [Mycobacterial resistance in patients during their 1st hospitalization]. PMID- 4219727 TI - [2 cephalosporinases of Pseudomonas aeruginosa]. PMID- 4219729 TI - [Modern principles for the organization of drug therapy in tuberculosis]. PMID- 4219726 TI - [The proteolytic system of Penicillium roqueforti. III. - Purification, properties and specificity of a protease inhibited by E.D.T.A]. PMID- 4219728 TI - Glycoprotein biosynthesis in splenic cells. IV. Subcellular localization of glycosyl - transferases. PMID- 4219730 TI - [Results of examinations at admission time to the study of fibrous lesions and pulmonary tuberculosis]. PMID- 4219732 TI - [Chemical structures and biological functions of mycobacterial cell walls with special reference to immunity against airborne infection by the strain M. tuberculosis H37Rv]. PMID- 4219733 TI - [Lysosome response to tuberculosis infection, evaluated on the basis of their cathepsic activity and the degradation of tuberculoproteins]. PMID- 4219731 TI - [Effectiveness, during the 1st year, of 3 treatment durations]. PMID- 4219735 TI - A clinical and sociomedical study for defaulting tuberculosis treatment. PMID- 4219734 TI - [Cooperative study of short-term antibacillary treatments in 14 French centers]. PMID- 4219736 TI - The economics of health. PMID- 4219737 TI - Development of functional connexions in the mammalian visual system. PMID- 4219738 TI - Selection of visual targets for the initiation of saccadic eye movements. PMID- 4219739 TI - Single unit firing patterns in the vestibular nuclei related to voluntary eye movements and passive body rotation in conscious monkeys. PMID- 4219740 TI - The role of vestibular and neck afferents during eye-head coordination in the monkey. PMID- 4219741 TI - Development of sensorially-guided reaching in infant monkeys. PMID- 4219742 TI - Movement without proprioception. PMID- 4219743 TI - Some examples of programmed limb movements. PMID- 4219744 TI - The activity of dentate neurons during an arm movement sequence. PMID- 4219745 TI - Relation of basal ganglia, cerebellum, and motor cortex units to ramp and ballistic limb movements. PMID- 4219746 TI - Single unit recording in the caudate nucleus during sessions with elaborate movements in the awake monkey. PMID- 4219747 TI - Pyramidal tract discharge in relation to movement performance in monkeys with partial anaesthesia of the movind hand. PMID- 4219748 TI - Role of occipito-frontal cortico-cortical connections in visual guidance of relatively independent hand and finger movements in rhesus monkeys. PMID- 4219749 TI - Gating of motor cortex reflexes by prior instruction. PMID- 4219750 TI - Cortical load compensation during voluntary elbow movements. PMID- 4219752 TI - Structure-activity correlations for N-substituted N-thioformylhydroxylamines on bacterial cells. PMID- 4219751 TI - Short review. Prospects for cancer immunochemotherapy. PMID- 4219753 TI - Formation of the red neotetrazolium formazan by reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase in the presence of triton X-100. PMID- 4219754 TI - Studies on dextranase. V. Activation of dextranase from Penicillium funiculosum IAM 7013 by Co2+. PMID- 4219755 TI - [Value of piribedil in the treatment of degenerative retinal vasculopathies]. PMID- 4219756 TI - [Treatment of eyelid epitheliomas by betatron]. PMID- 4219758 TI - Experiments with cholera toxin detoxified with glutaraldehyde. AB - Studies on the production, purification, and detoxification of cholera toxin are reported. The toxin was first partially purified with aluminium hydroxide and further purification was effected with Bio Gel A-5m and Sephadex G-75. The toxins were detoxified with glutaraldehyde; the toxoids so obtained, when injected into the skin of rabbits, appeared to have no residual toxicity. All the toxins were immunogenic. The toxoid partially purified with aluminium hydroxide retained most of its immunizing capacity, but the highly purified toxoids did not retain their capacity to stimulate antibody production in rabbits. PMID- 4219759 TI - Experiments on monkeys with cholera toxin partially purified and detoxified with formol and glycine. AB - Cholera toxoid partially purified and detoxified with formol and glycine and inoculated in monkeys proved safe. Histological examination revealed no changes in the skin of the animals treated. Blood samples taken from monkeys immunized with 2 doses of toxoid 12 days after the second inoculation revealed appreciable levels of antitoxin in the animals that had received two 100-mug doses of toxoid. The monkeys vaccinated with toxoid, when inoculated with challenge doses of cholera toxin, had the capacity to neutralize the toxin. Detoxification with formol and glycine may be the first step towards the preparation of a highly purified, innocuous, and antigenic cholera toxoid. PMID- 4219757 TI - Immunology of schistosomiasis. AB - This Memorandum, after summarizing the life cycle of the different species of human schistosome, reviews the present knowledge of the immunology of schistosomiasis. Each stage of the parasite contains antigen that may stimulate an immune response. However, at the moment there are no accepted serological in vitro tests that correlate with protection; this develops only after the host has experienced a living infection, which suggests that the stimulation of immunity is due to some metabolic process involving the release of protective antigen. The adult worm, however, seems to be able to escape the immune mechanism of the host. Specific antigens are also released by the eggs, and the immune response against these antigens seems to cause granuloma formation around the egg itself. The granuloma is the main lesion found in schistosomiasis. Evidence for protective immunity in experimental animals and man is reviewed, together with the possible mechanism by which the adult worm escapes the immune response of the host. A review of methods used for the diagnosis of schistosomiasis and a list of recommendations for further research are also included. PMID- 4219760 TI - The natural history of the antibody response to breast antigens. PMID- 4219764 TI - Immunological competence in non-human primates: differences observed in four species. PMID- 4219765 TI - Surface immunoglobulins in chronic lymphatic leukaemia, macroglobulinaemia and myelomatosis. PMID- 4219769 TI - Immunoelectrophoretic analysis of surface antigens in vegetative cells and spores of Bacillus cereus. PMID- 4219766 TI - Properdin levels in systemic lupus erythematosus and membranoproleferative glomerulonephritis. PMID- 4219770 TI - [Etiology of bacterial infections in superficial and deep wounds]. PMID- 4219768 TI - Rosette formation by mouse lymphocytes. II. T-cell specificities in a CRL subpopulation. PMID- 4219771 TI - [Interaction of poly I-C with membranes of cells stimulated to produce interferon and of cells not so stimulated]. PMID- 4219772 TI - [Epidemiological studies on Listeria infections: results of a serological study in the Cuneo province]. PMID- 4219773 TI - [Immunity to infection. A problem still current]. PMID- 4219774 TI - The effect of phenylalanine, glycine, lysine, thymidine and thalidomide upon the developmental age in Drosophila melanogaster. PMID- 4219775 TI - Need for long-term care of the inhabitants of Helsinki city. PMID- 4219776 TI - Adhesion of human blood platelets to glass and polymer surfaces. I. Studies with platelets in plasma. PMID- 4219777 TI - In vitro granulocyte-platelet rosette formation mediated by an IgG immunoglobulin. PMID- 4219778 TI - Biochemical foundations of preventive medicine: the study of abnormal enzymes. PMID- 4219779 TI - [Microbiological diagnostic of tuberculosis]. PMID- 4219780 TI - [Susceptibility of various bacteria isolated from patients with infections of the urinary tract against carbenicillin]. PMID- 4219781 TI - [Ecology of facultatively pathogenic bacteria with low demands in nutritive substances in hospitals (author's transl)]. PMID- 4219782 TI - [A quick and reliable method to recognize recent and older infections with rubella virus (author's transl)]. PMID- 4219783 TI - Beta-lactam antibiotics. I. Comparative structure--activity relationships of 6 acylaminopenicillanic acid derivatives and their 6-(D-alpha acylaminophenylacetamido) penicillanic acid analogues. PMID- 4219785 TI - Bacteriological studies on the combined action of aminoglycoside antibiotics and synthetic penicillins against Pseudomonas aeruginosa. PMID- 4219784 TI - Therapeutic efficacy of bicyclomycin for shigellosis experimentally induced in rhesus monkeys. PMID- 4219786 TI - Ultrasound localization of the kidneys for closed renal biopsy. PMID- 4219787 TI - The ultrasonic determination of renal transplant volume. PMID- 4219788 TI - The ultrasound findings in an obstructed afferent loop. PMID- 4219789 TI - The diagnosis of sextuplets by ultrasound-a case report. PMID- 4219790 TI - Ultrasound diagnosis of and cyst puncture guidance for a second unilateral renal cyst. PMID- 4219791 TI - A simple technique to determine the extent of abdominal aortic aneurysms of B mode sonography. PMID- 4219792 TI - Renal pelvic lipomatosis: a sonographic evaluation. PMID- 4219793 TI - Ultrasonic evaluation of postpartum sepsis with retained Dalkon shield. PMID- 4219794 TI - The gray scale echographic appearance of thyroid malignancy. PMID- 4219795 TI - B-mode ultrasonic examination of the testes. PMID- 4219796 TI - Simple device for the calibration of ultrasonic calipers. PMID- 4219797 TI - Acoustic microscopy of mammalian kidney. PMID- 4219798 TI - Pitfalls in the echographic evaluation of pancreatic disease. PMID- 4219799 TI - Gray scale ultrasonography in the diagnosis of thyroid swellings. PMID- 4219800 TI - Comparison of pelvic ultrasonography and pneumography for ovarian size. PMID- 4219801 TI - The inhibitory action of diazoxide on uterine activity in the subhuman primate: Placental transfer and effect on the fetus. PMID- 4219802 TI - The swivel football shoe: a controlled study. PMID- 4219803 TI - The case against ankle taping. PMID- 4219804 TI - Ankle injuries in sports. PMID- 4219805 TI - The ankle: soft tissue injuries. PMID- 4219806 TI - [Parenteral use of protein in complex antianemic measures after heart surgery]. PMID- 4219807 TI - [Role of parenteral nutrition in treatment of liver insufficiency]. PMID- 4219808 TI - [Effect of parenteral feeding on functional state of the liver in patients with acute cholecystitis according to enzymographic data]. PMID- 4219809 TI - [Ways of improvement of the preparation of casein hydrolysate for parenteral protein nutrition]. PMID- 4219810 TI - [Infusion solutions for parenteral feeding]. PMID- 4219811 TI - Failure of dialysis concentrate as a bactericidal agent. PMID- 4219812 TI - Enzyme therapy in Fabry's disease by renal transplantation. PMID- 4219813 TI - A new subcutaneous prosthetic A-V shunt: advantageous over the standard Quinton Scribner shunt and A-V fistula. PMID- 4219814 TI - Prediction of long term combined imuran ALG dosage. PMID- 4219815 TI - New long-stay inpatients. PMID- 4219816 TI - New long-stay patients. PMID- 4219817 TI - The hospital census as a sampling frame for studies of long-term psychiatric care. PMID- 4219818 TI - Influence of nitroglycerin on the isolated blood-perfused dog heart. PMID- 4219820 TI - [Editorial: Du antigens]. PMID- 4219819 TI - Effect of calcium ions on the optical rotation of the troponin complex, troponin A and troponin B. PMID- 4219821 TI - [Comparative study of various methods of identifying Du antigens]. PMID- 4219822 TI - [Determination of Du factor using Groupamatic. Comparison with manual technics. Report of 203,240 determinations]. PMID- 4219823 TI - [Du factor and routine blood typing]. PMID- 4219824 TI - [Hereditary disorders of cholesterol metabolism (literature survey)]. PMID- 4219825 TI - [Distribution of phenozymethylpenicillin in the body of healthy persons and patients with angina]. PMID- 4219826 TI - [Effectiveness of treatment of typhoid-paratyphoid bacterial carrier state with high doses of penicillin]. PMID- 4219827 TI - [Diagnostic evaluation of the bacteriolytic capacity of the blood serum in patients with lung cancer]. PMID- 4219828 TI - [Antibiotic sensitivity of actual bacterial flora from a urological clinic]. PMID- 4219829 TI - [Simultaneous assay of IgG and albumin in the cerebrospinal fluid]. PMID- 4219830 TI - [Standard values of human serum IgA. Variations in regard to age and sex]. PMID- 4219831 TI - [Utilization of the mixed-phages test for the differentiation of the principal species belonging to group D streptococci (author's transl)]. PMID- 4219832 TI - [The microbiological pollution of North Sea and English Channel shore (author's transl)]. PMID- 4219833 TI - [Comparative studies on the sensitivity of the Ouchterlony method and cross electrophoresis. Species specificity--immunological identification of sperma]. PMID- 4219834 TI - Purification and properties of 3-hexulose phosphate synthase and phospho-3 hexuloisomerase from Methylococcus capsulatus. AB - 3-Hexulose phosphate synthase and phospho-3-hexuloisomerase were purified 40- and 150-fold respectively from methane-grown Methylococcus capsulatus. The molecular weights of the enzymes were approximately 310000 and 67000 respectively, as determined by gel filtration. Dissociation of 3-hexulose phosphate synthase into subunits of molecular weight approx. 49000 under conditions of low pH or low ionic strength was observed. Within the range of compounds tested, 3-hexulose phosphate synthase is specific for formaldehyde and d-ribulose 5-phosphate (forward reaction) and d-arabino-3-hexulose 6-phosphate (reverse reaction), and phospho-3-hexuloisomerase is specific for d-arabino-3-hexulose 6-phosphate (forward reaction) and d-fructose 6-phosphate (reverse reaction). A bivalent cation is essential for activity and stability of 3-hexulose phosphate synthase; phospho-3-hexuloisomerase is inhibited by many bivalent cations. The pH optima of the two enzymes are 7.0 and 8.3 respectively and the equilibrium constants are 4.0x10(-5)m and 1.9x10(2)m respectively. The apparent Michaelis constants for 3 hexulose phosphate synthase are: d-ribulose 5-phosphate, 8.3x10(-5)m; formaldehyde, 4.9x10(-4)m; d-arabino-3-hexulose 6-phosphate, 7.5x10(-5)m. The apparent Michaelis constants for phospho-3-hexuloisomerase are: d-arabino-3 hexulose 6-phosphate, 1.0x10(-4)m; d-fructose 6-phosphate, 1.1x10(-3)m. PMID- 4219835 TI - [Norrie's disease (observation of a family)]. PMID- 4219839 TI - Specific antisera to Clr. Quantitation of Clr in normal and pathological human sera. PMID- 4219840 TI - Sequential cell-mediated immune responses in experimental gingivitis in man. PMID- 4219838 TI - Nature of the antigen present in the cerebrospinal fluid and serum of patients with group A meningococcal meningitis. PMID- 4219842 TI - Inactivation of C1 in rheumatoid synovial fluid, purfied C1 and C1 esterase, by gold compounds. PMID- 4219843 TI - Analytical study of salivary immunoglobulins in multiple myeloma. PMID- 4219844 TI - PHA-induced lymphocyte transformations in leucocyte cultures from malarious, malnourished and control Gambian children. PMID- 4219845 TI - Deficit of spatial reversal in monkey with frontal lesions. PMID- 4219846 TI - Some physiological and behavioural changes associated with oestrus and pregnancy in the squirrel monkey (Saimiri sciureus). PMID- 4219847 TI - Glutaraldehyde fixation of boar spermatozoa for acrosome evaluation. PMID- 4219848 TI - Radiosensitivity of synchronized Tetrahymena pyriformis W. cells. PMID- 4219849 TI - A proline-dependent ATP-32Pi exchange in Bacillus sutilis B3 producing mycobacillin. PMID- 4219850 TI - Seasonal variation in personal health expenditure of rural populations. PMID- 4219851 TI - Comparative sensitivity of suckling mice and Vero cells for primary isolation of chikungunya virus. PMID- 4219852 TI - Studies on host-parasite relationships of Ilan strain of Schistosoma japonicum in animals. 2. Worm recovery rate. PMID- 4219853 TI - [Brucellosis in the female genital tract]. PMID- 4219854 TI - The effects of intravenous protein--calorie supplementation on the tissue composition of postoperative body weight loss. PMID- 4219855 TI - Successful resuscitation in diabetic ketoacidosis: a strong case for the use of bicarbonate. PMID- 4219856 TI - Gonococcaemia with arthritis, dermatitis and myocarditis. PMID- 4219857 TI - Lactic acidosis and hyperamylasaemia associated with phenformin therapy. PMID- 4219858 TI - [Anti-D (Rh) antibodies in the amniotic fluid]. PMID- 4219859 TI - [Comparative study of various parameters in the evaluation of isoimmunization against the negative Rh factor]. PMID- 4219860 TI - [The behavior of facial buds in chick embryos. Double malformations of the frontal process]. PMID- 4219861 TI - [Epilepsies in the adult. Can we distinguish progressive types?]. AB - Electro-clinical, neuro-radiologic and socio-professional study of 100 epileptic adults, followed by the same physician during 12 to 20 years (average 15 1/2 years), now 30 to 75 years old, all cases of evolutive pathology being excluded. The evolution statistically is more favourable when the epilepsy: has developed late (between 21 and 30 years); ils described as "idiopathic", or with small primary lesion; is characterized by primary generalized fits with strong convulsive component, occurring preferably at awaking. The evolution is less favourable, even unfavourable, when the epilepsy: is secondary to a severe encephalopathy or to extensive focal lesions; has developed during childhood; is characterized by fits with partial start, little tendency to secondary convulsive generalization, and occurring any time of the day or bound to sleep. PMID- 4219862 TI - Relationships between intraocular pressure and the morphology of the outflow apparatus. PMID- 4219864 TI - Biosynthesis of rat small seminal fructose as influenced by in vitro tissue excitation. PMID- 4219863 TI - Neurologic effects of repeated exposures to high-pressure heliox atmospheres. PMID- 4219865 TI - Clinical observation of the prevention of RH isoimmunization with immunoglobulin anti-D. PMID- 4219866 TI - Protein malnutrition: correlation between anthropometric and biochemical assessment. AB - Three hundred and eighty-six children aged 12-59 months, suffering from protein calorie malnutrition were studied. Middle arm circumference and triceps skin-fold measurements were taken and from these values, middle arm muscular circumference was calclated. Simultaneously, the serum amino-acid balance was determined. The same measurements were carried out in 132 healthy control children of the same age group. These showed that middle arm muscular circumference does not change within the age groups studied, and with its value the amino-acid balance showed an inverse correlation. It is concluded that the severity of protein imbalance in malnutrition can be estimated on the basis of both middle arm muscular circumference and amino-acid balance. In view of its simple technique the former parameter is given preference. PMID- 4219867 TI - Metabolic and hormonal effects of alternate infusion of hypertonic glucose and aminosol-glucose in premature infants. AB - The metabolic and hormonal effects of a short term (24-36 hrs), alternating intravenous administration of hypertonic (16%) glucose and Aminosol-glucose were investigated in premature infants. The majority of the infants under 1 500 g showed pathological signs and did not tolerate oral feeding. The purpose of the study was to explore an intravenous alimentation program capable of ensuring an improved amino acid utilization in terms of nitrogen balance, and to prevent some of the adverse effects of the amino acid mixture. It was thought that the hormonal state created by 16% glucose might increase the capacity of the tissues to utilize the amino acids. The relevant findings were as follows. 1. Plasma free fatty acids and amino acids decreased, plasma insulin and growth hormone increased markedly in response to 16% glucose. The plasma aminogram indicated a profound redistribution of amino acids. 2. Aminosol-glucose infusion after the 16% glucose, increased the concentration of amino acids, but only to the starting level. Thus the previously decreased alpha-amino nitrogen content allowed to avoid a hyperaminoacidaemia and a marked distortion of the plasma amino acid pattern. Administration of the amino acid-glucose mixture usually failed to maintain the previously stimulated insulin and growth hormone secretion. 3. The hormonal and metabolis responses to the intermittent infusion of hypertonic glucose and Aminosol-glucose were not associated with an improved nitrogen utilization. More than 50% of the administered amino acid nitrogen was excreted. 4. The metabolic acidosis observed under these condition was found to be variable, and practically compensated. PMID- 4219868 TI - [Phototherapy and treatment with phenobarbital in hemolytic disease of newborn due to Rh-incompatibility]. PMID- 4219869 TI - [Serum proteins and red cell enzymes in Callithrix jacchus (author's transl)]. PMID- 4219871 TI - Toxicity and mutagenicity of dimethyl sulfoxide in two strains of Drosophila melanogaster. PMID- 4219870 TI - The lethal interaction between the genes prune (pn) and killer of prune (Kpn) in Drosophila melanogaster. PMID- 4219872 TI - Newborn genetic screening as a concept in health care delivery: a critique. PMID- 4219873 TI - Mass screening and genetic counseling in mendelian disorders. PMID- 4219874 TI - Circulating tissue antigens. I. Tissue antigens in serum of patients with diseases involving injury of the liver and of other organs. PMID- 4219875 TI - Plasma volume expansion and increased serum viscosity in myeloma and macroglobulinaemia. PMID- 4219876 TI - The autosomal recessive mode of inheritance of C1r deficiency in a large Puerto Rican family. PMID- 4219879 TI - Heterophilic antibodies in relation to malarial infection: population and experimental studies. PMID- 4219880 TI - Comparative study on two labelled antimonial drugs, Bilharcid and tartar emetic using monkeys. PMID- 4219881 TI - The fate and behaviour of antimonial drugs labelled with 124Sb in bilharzial subjets. PMID- 4219882 TI - The innervation of the human vestibular sensory regions. PMID- 4219883 TI - Xenografts. PMID- 4219884 TI - Porcine aortic valves for replacement of human heart valves. PMID- 4219885 TI - [Green nails]. PMID- 4219886 TI - [Sterilization in endodontics]. PMID- 4219887 TI - [A cingulate invagination and its complications. An attempt at a dysembryo genetic interpretation]. PMID- 4219888 TI - [Mixed vaccine against bacterial anthrax and symptomatic anthrax]. PMID- 4219889 TI - Viral cardiomyopathy. PMID- 4219890 TI - Pathology of Chagas' cardiomyopathy. PMID- 4219891 TI - Experimental cardiomyopathies in poikilotherms. PMID- 4219892 TI - Natural history of diverse cardiomyopathies. PMID- 4219893 TI - [Serological behavior of rheumatoid arthritis as related to blood groups and subgroups]. PMID- 4219894 TI - Lepers, madmen--who's next? PMID- 4219895 TI - The diagnosis and psychopathology of schizophrenia in New York and London. PMID- 4219896 TI - Study of protein reactivity in rat liver ribosomes. Effect of RNA addition to autodigested ribosomes. PMID- 4219897 TI - Studies of the RNA and protein moieties of the larger subribosomal particle of rabbit reticulocytes. PMID- 4219898 TI - Hydatid cyst of the brain as an epileptogenic factor. PMID- 4219899 TI - Effect of epileptogenic stimulation on the acetylcholine content of rat hippocampus. PMID- 4219901 TI - [Use and usefulness of disodium cromoglycate in occupational allergic asthma]. PMID- 4219900 TI - [Further observations on the gastrointestinal effects of 3,3'-dihydroxy-dibutyl ether]. PMID- 4219902 TI - [Pharmacodynamic study on the acoustic "cannon sound" findings; physiopathological considerations]. PMID- 4219903 TI - [Morquio's syndrome: case of complete congenital atrioventricular block accompanied by bone malformations and mental deficiency. Implantation of a permanent pacemaker]. PMID- 4219904 TI - [Respiratory manifestations in Waldenstrom's macroglobulinemia (apropos of 5 cases)]. PMID- 4219905 TI - [Corneal thesaurismosis: Morquio's disease]. PMID- 4219906 TI - [A case of nevoxanthoendothelioma]. PMID- 4219907 TI - Some aspects of immunity in patients with cystic fibrosis. PMID- 4219908 TI - Studies of serum complement in the hypocomplementaemic nephritides. PMID- 4219909 TI - Diffuse normolipaemic plane xanthomatosis. An abnormal complement component profile. PMID- 4219911 TI - [Dental gold alloys]. PMID- 4219912 TI - [Gold silver palladium alloys and dental white gold]. PMID- 4219910 TI - The immunohistological detection of intracellular immunoglobulin in formalin paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique. PMID- 4219913 TI - [Testing of silver alloys for dental casting]. PMID- 4219914 TI - [Test of chromium-cobalt alloys for dental casting]. PMID- 4219915 TI - [Dental alloys and cadmium]. PMID- 4219916 TI - [Some questions on the A.D.A. standard of gold alloys]. PMID- 4219917 TI - Estrogen-binding in vitro by DMBA-induced rat mammary tumors: its relationship to hormone responsiveness. PMID- 4219918 TI - [Bacillus subtilis mutant strains, producers of alkaline proteinases]. PMID- 4219920 TI - [Mutagenic effect of thio-TEPA in laboratory mice. I. Chromosome aberrations in somatic and germ cells of male mice]. PMID- 4219921 TI - [Genetic processes in irradiated populations. II. Effect of chronic x-radiation on the concentration of visible mutations in laboratory populations of Drosophila melanogaster]. PMID- 4219919 TI - [Mutagenic and teratogenic activity of Nevigramon]. PMID- 4219923 TI - [Mutagenic effect of thio-TEPA in laboratory mice. II. Cytogenetic analysis of damage to bone marrow cells]. PMID- 4219922 TI - [Mapping of the Bacillus subtilis chromosome region carrying the rec 342 mutation (mutation decreasing the activity of ATP-dependent deoxyribonuclease)]. PMID- 4219924 TI - [Isolation from a natural population of strains of Drosophila with increased radiosensitivity]. PMID- 4219925 TI - [Bacillus subtilis mutants with modified DNA donor ability in spontaneous transformation. IV. Relation of transformation ability to donor activity]. PMID- 4219926 TI - [UV-mutagenesis in Bacillus subtilis. II. Repair of the biological activity of cellular DNA in conditions determining the sensitivity of cells to the mutagenic action of ultraviolet light]. PMID- 4219927 TI - [Genealogical analysis of dominant mutation in neurofibromatosis (Recklinghausen's disease)]. PMID- 4219928 TI - [Genetics and selection of the entomopathogenic fungus Beauveria bassiana (Bals.) Vuill. II. Virulence of auxotrophic mutants of Beauveria bassiana on Drosophila melanogaster]. PMID- 4219929 TI - [Genetic analysis of ring chromosome variability in Drosophila. I. Relation to sex and heterozygote inversions, lethality]. PMID- 4219930 TI - [Analysis of somatic cell chromosomes in patients treated with antineoplastic agents]. PMID- 4219931 TI - [Effect of low temperature on the variability of ring chromosomes in Drosophila]. PMID- 4219933 TI - [Genetic processes in irradiated populations. I. Effect of chronic x-irradiation on the frequency and concentration of lethal and semilethal mutations in the 2d chromosome in laboratory populations of Drosophila melanogaster]. PMID- 4219932 TI - [Delayed cytogenetic effect of acute irradiation of monkeys. II. Frequency of chromosome anomalies in monkey peripheral blood lymphocytes]. PMID- 4219934 TI - [Genetic analysis of variability in Drosophila ring chromosomes. II. Effect of parental age]. PMID- 4219935 TI - About the normal values of the acid-base and oxygen indices in small laboratory animals--rats and rabbits. PMID- 4219936 TI - Endogenic humoral effects on the formation of antitoxins. PMID- 4219937 TI - A radiographic study of the ethmoidal latticed labyrinths from birth to the age of thirteen. PMID- 4219938 TI - Histochemical studies of some dehydrogenases in dental tooth germ in vivo and in culture. PMID- 4219939 TI - Relationship between the respiratory and lipopexic function of the lungs in some non-specific lung diseases depending on age. PMID- 4219940 TI - Changes in glucose regulation following stomach resection according to Billroth II. PMID- 4219941 TI - Changes in cholinesterase activity in white rats, after several injections of TMB 4 and atropine, following treatment with parathion. PMID- 4219942 TI - Development of trichomonas vaginalis upon a medium "Trimed" containing serum of various animal origin. PMID- 4219943 TI - Juniper bath treatment of the neurasthenic neurosis. PMID- 4219944 TI - Schemes on the application of BCG to skin cancer. PMID- 4219945 TI - Radio-active gold as an indicator in the study of the laxative effectiveness of some medicines. PMID- 4219946 TI - Comparison between the results of the 131I--rose bengal functional examination and the scintigraphia in patients with liver diseases. PMID- 4219947 TI - Congenital lobar emphysema--pathoanatomic studies of three cases. PMID- 4219948 TI - Forensic medical and forensic chemical study of acute lethal poisinnins with thiodan. PMID- 4219949 TI - [Spectral and photochemical properties of allophycocyanin from blue-green alga in the course of denaturation]. PMID- 4219951 TI - Adjuvant activity in delayed hypersensitivity of the peptidic part of bacterial peptidoglycans. PMID- 4219950 TI - Transepithelial potential difference in toad urinary bladder is not due to ionic diffusion. PMID- 4219952 TI - Effects of dietary supplementation on the humoral immune response of malnourished mice. PMID- 4219953 TI - [Manifestations of the eyeless-dominant gene in Drosophila melanogaster]. AB - A phenogenetic study was carried out of the eyD-mutation in Drosophila melanogaster which reduces the eye and quantitatively affects different regions of the head capsule originating from the eye imaginal disc. It was shown that the change in eye size is connected causally with changes in certain regions of head capsule: increase in chaetae number or duplication in different regions of the head capsule may be due to the degeneration of presumptive ommatidia. It is supposed that the variable response of chaetae number to the decrease in eye size depends on the origin of chaetae and their topography at different stages of the disc development. PMID- 4219954 TI - [Formation of the respiratory enzyme apparatus in plant cells. III. Antigenic spectra of mitochondria in the root tip of corn]. AB - By means of one- and two-dimensional (cross) immunoelectrophoresis, immunoelectro diffusion and radial immunodiffusion, about 20 antigens were detected in mitochondria of meristem, zone of elongation and mature cells, among which some were identified by zymographic methods. The differentiation of root cells is not accompanied by qualitative changes in antigenic spectra of mitochondria and changes in the ratio of antigens (including glutamate and malate dehydrogenases) suggest that mature mitochondria develop from preexisting ones by gradual quantitative changes which are due to different rate of synthesis of constituent proteins. PMID- 4219955 TI - [A comparison of bacterial RNA-polymerase RNA synthesis on polytene Drosophila chromosomes with transcription in living cells]. AB - The incorporation of 3H-uridine in different regions of polytene chromosomes in live cells of the Drosophila melanogaster salivary glands was compared with the incorporation of 3H-UTP in the same regions under the incubation of cytological preparations of these chromosomes with the E. coli RNA polymerase. The label distribution by regions was compared with the DNA content in them. Individual regions of chromosomes differ by 3H-uridine incorporation in live cells to a much greater extent than by 3H-UTP incorporation in vitro under the incubation with a non-homologous enzyme. RNA synthesis in an exogenous enzyme depends on the DNA content in different chromosome regions to a much greater extent than RNA synthesis in vivo. The correlation of label distribution after 3H-uridine incorporation in live cells and after RNA synthesis in vitro on the preparations by the bacterial RNA polymerase is, correspondingly, very low. This enzyme forms, however, RNA's on puffs 2-3 times more actively than on the same regions in non puffing state but this difference is dozens of times greater in live cells. RNA synthesis in vitro is, thus, non-specific and does not correspond practically to the intensity of RNA synthesis on the same chromosome regions in live cells. At the same time, as in live cells, the E. coli enzyme synthesizes twice more RNA on the single X-chromosome of males (1X2A) than on each of X-chromosomes of diploid (2X2A) and triploid (3X3A) females or superfemales (3X2A), whereas in intersexes (2X3A) X-chromosomes display intermediate template activity. Thus, RNA synthesis by a heterologous enzyme in vitro does not differ by this index from the synthesis in live cells. It is suggested that differences in the template activity of X-chromosomes in vitro depending on the sex index (X : A) are due to different degree of DNP condensation in these chromosomes. In spite of differences in the degree of condensation, the male X-chromosome binds on the fixed preparation approximately the same amount of thymus histone F1 carrying fluorochrome as each of two female X-chromosomes. Hence, there is no sharp difference between the male and female X-chromosomes by the number and length of DNA regions accessible for interaction with exogenous proteins. On the basis of the data obtained, a hypothesis about two levels and, respectively, two mechanisms of control gene activity in animal chromosomes is considered. The first mechanism is, supposedly, based on decondensation of DNP appears to result in that the same proteins-regulators in the same amount activate corresponding genes in X-chromosome in males twice more strongly than in females. PMID- 4219956 TI - [Interaction of the homoeotic mutations aristapedia and polycomb during ontogenesis of Drosophila melanogaster]. AB - The manifestation of 5 alleles of aristapedia and 2 alleles of Polycomb was studied in initial stocks and in flies of Pc ssa/+ssa genotype. Mutual enhancement of homoeotic effects of ssa and Pc genes was observed. Differences in intergenic interaction were aristapedia, rather than Polycomb specific. Possible role of homoeotic mutations as mutations of regulatory genes and the bearing of the data on their interaction on the results of clonal analysis of homoeosis are discussed. PMID- 4219957 TI - Side effects of clonazepam therapy. PMID- 4219958 TI - Hypercalcaemia and epilepsy. PMID- 4219959 TI - Partial status epilepticus with speech arrest. PMID- 4219960 TI - Neuro-ophthalmic deterioration after burns. PMID- 4219961 TI - [Osseous metaplasia of the endometrium]. PMID- 4219962 TI - Damage to the inner ear in mastoid surgery. PMID- 4219963 TI - Sex-dependent behavioral effects of cerebral cortical lesions in the developing rhesus monkey. AB - Male rhesus monkeys with orbital prefrontal lesions were imtpaired on behavioral tests at 2(1/2) months of age whereas similar deficits were not detected in females with comparable lesions until 15 to 18 months of age. The results suggest that the maturation of a cortical region in the primate brain proceeds at different tempos in males and females. PMID- 4219964 TI - Size and scaling in human evolution. AB - Our general conclusion is simply stated: many lineages display phyletic size increase; allometric changes almost always accompany increase in body size. We cannot judge adaptation until we separate such changes into those required by increasing size and those serving as special adaptations to changing environments. In our view, the three australopithecines are, in a number of features, scaled variants of the "same" animal. In these characters, A. africanus is no more "advanced" than the larger, more robust forms. The one early hominid to show a significant departure from this adaptive pattern toward later hominids cranially, dentally, and postcranially-is H. habilis from East Africa. The australopithecines, one of which was probably a precursor of the Homolineage, were apparently a successful group of basically vegetarian hominids, more advanced behaviorally than apes (87), but not hunter-gatherers. The fossil hominids of Africa fall into two major groupings. One probable lineage, the australopithecines, apparently became extinct without issue; the other evolved to modern man. Both groups displayed steady increase in body size. We consider quantitatively two key characters of the hominid skull: cranial capacity and cheek tooth size. The variables are allometrically related to body size in both lineages. In australopithecines, the manner of relative growth neatly meets the predictions for functional equivalence over a wide range of sizes (negative allometry of cranial capacity with a slope against body weight of 0.2 to 0.4 and positive allometry of postcanine area with a slope near 0.75). In the A. africanus to H. sapiens lineage, cranial capacity increases with positive allometry (slope 1.73) while cheek teeth decrease absolutely (slope - 0.725). Clearly, these are special adaptations unrelated to the physical requirements of increasing body size. We examined qualitatively other features, which also seem to vary allometrically. Of course, many characters should be studied quantitatively, but we think that the scheme outlined here should be treated as the null hypothesis to be disproved. PMID- 4219965 TI - Neural basis of orientation perception in primate vision. AB - Orientational differences in human visual acuity can be related parametrically to the distribution of optimal orientations for the receptive fields of neurons in the striate cortex of the rhesus monkey. Both behavioral measures of acuity and the distribution of receptive fields exhibit maximums for stimuli horizontal or vertical relative to the retina; the effect diminishes with distance from the fovea. The anisotropy in the neuronal population and in visual acuity appear to be determined by postnatal visual experience. PMID- 4219966 TI - The use of a diphosphonate in para-articular ossifications after total hip replacement. A clinical study. PMID- 4219967 TI - [Mechanism of action of nitroglycerin and its effects on hemodynamics and myocardial regional flow in angina pectoris]. PMID- 4219968 TI - [Cancerization of bladder diverticula]. PMID- 4219969 TI - Autoperfusing heart-lung preparation: prolonged survival by extracorporeal symbiosis. PMID- 4219970 TI - [Drug therapy of acute cerebral ischemia. Clinical study]. PMID- 4219971 TI - [BIREMA: a biomedical information center serving South America]. PMID- 4219972 TI - The relationship between precursor and mature forms of the 23S ribosomal RNA. PMID- 4219973 TI - Comparison of RNA sequences from widely divergent species. PMID- 4219974 TI - A new isozyme of triose phosphate isomerase specific to hominoids. PMID- 4219976 TI - [Fractures of the ankle]. PMID- 4219979 TI - The isolation and identification of an antigen for the diagnosis of bovine mastitis by radial immunodiffusion. PMID- 4219975 TI - Doublet frequency analysis of bacterial DNAs. PMID- 4219980 TI - [Detection of serum fibrinogen degradation products using Merskey's technic, Apropos of 169 cases]. PMID- 4219981 TI - [Value of the use of glutaraldehyde for the sensitization of red cells in Merskey's technic]. PMID- 4219982 TI - [Diffuse pulmonary amylosis during Waldenstrom's macroglobulinemia]. PMID- 4219983 TI - [Prevention of sensitivity to Rh factor by immunosuppressive drugs]. PMID- 4219984 TI - [Osseous metaplasia of the endometrium]. PMID- 4219985 TI - Vibrations of the temporal bone due to head injury. PMID- 4219986 TI - A long-term study of children born to diabetic mothers. (With special reference to occurrence of late neurological abnormalities). PMID- 4219987 TI - Parenteral hyperalimentation: a beginning. PMID- 4219988 TI - Intravenous Additive program: progress at Naval Hospital Portsmouth. PMID- 4219989 TI - Morphology and serum complement levels in membranoproliferative glomerulonephritis. PMID- 4219990 TI - Prostaglandins in nephrology. PMID- 4219991 TI - The functional significance of complement. PMID- 4219993 TI - Influence of the preservation technique on the early function of the kidney after reimplantation. PMID- 4219992 TI - Parathyroid function in renal insufficiency. PMID- 4219994 TI - Are there contraindications to renal transplantation? PMID- 4219995 TI - Recent drug management advances in renal insufficiency. PMID- 4219996 TI - Renal insufficiency in lupus nephritis. PMID- 4219997 TI - The nature and pathogenesis of systemic amyloidosis. PMID- 4219998 TI - Complement deposition in the kidney. PMID- 4219999 TI - Evidence for activation of the alternate pathway in glomerulonephritis. PMID- 4220000 TI - Complement and mesangiocapillary glomerulonephritis: the role of complement deficiency in glomerulonephritis. PMID- 4220002 TI - The C3 nephritic factor (C3NeF) and the heat labile complement inactivator (HLCI) in chronic hypocomplementemic mesangioproliferative glomerulonephritis. PMID- 4220001 TI - Activation of complement in human nephritis. PMID- 4220003 TI - Gonadotropin and prolactin secretion in human pseudocyesis: effect of synthetic luteinizing hormone-releasing hormone (LH-RH) and thyrotropin releasing hormone (TRH) PMID- 4220004 TI - [Serum level of thyroxine (T4) and triiodothyronine (T3) in patients with congenital goiter]. PMID- 4220006 TI - M--craniocarpotarsal dystrophy (whistling face syndrome) in two families. PMID- 4220005 TI - [External radiotherapy in the treatment of cancer of the thyroid body (apropos of 224 cases)]. PMID- 4220007 TI - N--variable expressivity in craniocarpotarsal dysplasia. PMID- 4220008 TI - S--the whistling-face syndrome: report of a case with a renal anomaly. PMID- 4220009 TI - The REEDS syndrome. PMID- 4220010 TI - The Roberts syndrome. AB - The Roberts syndrome appears to follow an autosomal recessive mode of inheritance. The cause of the abnormalities probably exerts its effect prior to the seventh week of gestation and only on a few organ systems undergoing development during this time. The peculiar morphologic features of metaphase chromosomes of the one individual who has been studied extensively are unexplained. PMID- 4220011 TI - Some bacteriological considerations of soft lens wear. PMID- 4220012 TI - Biophysical intrapartal fetal monitoring. PMID- 4220013 TI - Neurologic problems in perinatology. PMID- 4220015 TI - [Prognostic experiences in the long-term differential therapy of chronic aggressive hepatitides]. PMID- 4220014 TI - [Emergency endoscopy a method for the improvement of diagnosis in acute gastrointestinal hemorrhages]. PMID- 4220016 TI - Gel filtration of thyroxine--binding proteins. Identification of human serum protein fractions separated on Sephadex G 100. PMID- 4220017 TI - Radioimmunoassay of plasma LH in rat: basal levels and effects of synthetic LH RH. PMID- 4220018 TI - A correlative study of thyroid mast cells and thyroid function in the rat. PMID- 4220019 TI - Gel filtration of thyroxine--binding proteins. Identification of rat plasma protein fractions separated on Sephadex gels. PMID- 4220020 TI - Observations on plaque morphology of Pseudomonas pyocynea bacteriophages. PMID- 4220021 TI - [14 c/s positive spikes with post-traumatic epilepsy]. PMID- 4220023 TI - [Chagas' disease and infertility]. PMID- 4220022 TI - [Clinical, parasitological, hematological, pathological and immunological studies in monkeys experimentally infected with Trypanosoma rhodesiense]. PMID- 4220024 TI - [Simple radial immunodiffusion of C.S.F.: methods and applications (author's transl)]. PMID- 4220025 TI - Pathophysiological role of plasma kinins in malaria. PMID- 4220026 TI - [Gamma globulins in the cerebrospinal fluid determined by radial immunodiffusion. Their importance in multiple sclerosis]. PMID- 4220027 TI - [D-cycloserine and germination of Bacillus cereus spores]. PMID- 4220028 TI - Presubiculum afferents to the entorhinal area and the Papez circuit. PMID- 4220029 TI - Projections of auditory responsive cortex in the squirrel monkey. PMID- 4220030 TI - Interhemispheric communication between extraoccipital visual areas in the monkey. PMID- 4220031 TI - Certain biochemical correlates of intense serotonin histofluorescence in the brain stem of the neonatal monkey. PMID- 4220032 TI - Impaired orientation after primate tectal lesions. PMID- 4220034 TI - The role of the institution and the concept of parallel services. PMID- 4220033 TI - Immunochemical studies of brain glutamate decarboxylase and GABA-transaminase of six inbred strains of mice. AB - Six different inbred strains of mice (C57BL/6J, CBA/CaJ, CE/J, DBA/2J, LP/J and RF/J) were compared in terms of specific activities and immunochemical properties of brain L-glutamate decarboxylase (GAD) and gamma-aminobutyrate transaminase (GABA-T), the enzymes responsible for the synthesis and degradation of GABA, respectively. GAD from the brains of the different strains was indistinguishable on the basis of specific activities, double diffusion tests, immunoelectrophoresis and inhibition by antibody. However, microcomplement fixation tests showed GAD from DBA and C57BL mice to be most distinctly different from GAD extracted from the Swiss mouse, from which the original antigen was prepared and that the enzyme from the CE, LP and RF also differed. Similar fixation curves were obtained for the GAD from CBA and Swiss mice. GABA-T from the different strains was indistinguishable on the basis of all the tests employed. PMID- 4220035 TI - Some issues in manpower for parallel services. PMID- 4220036 TI - Cost-effective analysis. A quandary for geriatric health care systems. PMID- 4220037 TI - Symposium--long-time care: research, policy, and practice. Relocation research and social policy. PMID- 4220038 TI - Approaches to improving the quality of long-term care for older persons. PMID- 4220039 TI - [Determination of chorionic somatomammotropin hormone during isoimmunization by anti-D[]. PMID- 4220041 TI - Sodium cromoglycate 2 per cent solution in perennial rhinitis: a clinical and histological study. PMID- 4220040 TI - [Prediction of fetal damage in anti-RH isoimmunization. 2 statistical approaches]. PMID- 4220042 TI - Specific granules in human and nonhuman vertebrate cardiocytes. PMID- 4220044 TI - Proceedings: Macroscopic organisation of Ligamenta flava in cercopithercinae. PMID- 4220043 TI - [Azo dyes and embedding (preliminary note)]. PMID- 4220045 TI - Proceedings: Vitamin deficiencies and brain metabolism. PMID- 4220046 TI - Serum diamine oxidase in pregnancy. PMID- 4220047 TI - The significance of dental epithelium in the pathogenesis of periodontal disease. PMID- 4220048 TI - [Regulatory mutants with regard to nucleoside catabolism genes in Escherichia coli K-12, produced by using F' strains]. PMID- 4220049 TI - [Cytogenetic effect of ethylenimine derivatives in cultures of human lymphocytes. I. Experimental findings and mathematical verification of quantitative patterns]. PMID- 4220050 TI - [Experimental verification of the possibility of using a genetico-statistical model for assessment of unequilibrated populations]. PMID- 4220051 TI - [Prolonged mutagenesis in a culture of human leukocytes]. PMID- 4220052 TI - [Relationship between the interval of time between application and the cytogenetic effect of combined x-rays and thio-TEPA in the cells of human embryos cultivated in vitro]. PMID- 4220053 TI - [Cytogenetic effect of ethylenimine derivatives in human lymphocyte cultures. III. An analysis of the types of chromosome aberrations]. PMID- 4220055 TI - [The communicative behavior of the crab-eating monkey Macaca fascicularis Raffles 1821]. PMID- 4220054 TI - [Reproductive biology and behavior of Cebuella pygmaea and Tamarin tamarin (Primates, Platyrrhina, Callithricidae)]. PMID- 4220056 TI - Cutis marmorata telangiectatica congenita. PMID- 4220058 TI - [Development of anti Rh antibody titers after labor of immunized women. Application to the immune plasma sample by plasmapheresis]. PMID- 4220057 TI - Acanthosis nigricans and hypovitaminosis A. response to topical vitamin A acid. PMID- 4220059 TI - [Study of the transplacental passage of fetal erythrocytes in 100 abortions]. PMID- 4220060 TI - [2 cases of Rh factor isoimmunization followed by amniocentesis]. PMID- 4220062 TI - [Prevention of post-transfusional feto-maternal immunizations]. PMID- 4220061 TI - [Repeated plasmapheresis in severe Rhesus isoimmunization]. PMID- 4220063 TI - [Immunologic and pathogenic problems posed by hemolytic diseases caused by Rhesus incompatibility of the firstborn infant]. PMID- 4220064 TI - [2 cases of ossification of the uterine mucosa]. PMID- 4220065 TI - [Severity of perinatal effects in feto-maternal Rhesus incompatibility. Circumstances of immunization as a function of parity and gestation]. PMID- 4220066 TI - [Control of the menstrual cycle and fertility by progesterone in Macaca fascicularis]. PMID- 4220067 TI - [Ultrastructure of the human fetal membranes]. PMID- 4220068 TI - Repercussions of legal abortion on subsequent pregnancies. PMID- 4220069 TI - [Study of levels of human chorionic somatomammotropin in the plasma and amniotic fluid during normal and pathologic pregnancies]. PMID- 4220070 TI - [Value of determination of human chorionic somatomammotropin in the plasma and amniotic fluid in Rhesus immunization]. PMID- 4220071 TI - [Generalized epileptic crises and focal cortical lesion. (A propos of a post traumatic frontal epilepsy)]. PMID- 4220072 TI - [Note on a case of Unverricht's disease treated with Ro 05-4023 (26 month follow up)]. PMID- 4220074 TI - A special tupaia cage for the continuous detection of locomotor activity under the auto- or the self-control of light-darkness rhythms. PMID- 4220073 TI - [Thalamic extension of paroxysmal discharges in a photosensitive baboon Papio papio]. PMID- 4220075 TI - [The bacteriocinogeny of corynebacteria and neisseria]. PMID- 4220076 TI - Transduction of a streptomycin R-factor from Mycobacterium smegmatis to Mycobacterium tuberculosis H37Rv. PMID- 4220077 TI - A new case-finding programme in a region of Taiwan. PMID- 4220078 TI - The meaning and structure of species as applied to mycobacteria. PMID- 4220079 TI - A family outbreak of tuberculosis in Bristol in 1973 with two cases of tuberculous meningitis. PMID- 4220080 TI - A study in Hong Kong to evaluate the role of pretreatment susceptibility tests in the selection of regimens of chemotherapy for pulmonary tuberculosis--second report. A Hong Kong Tuberculosis Treatment Services/British Medical Research Council Investigation. PMID- 4220081 TI - A study of delayed hypersensitivity, lymphocyte transformation and leucocyte migration inhibition by M. xenopi and M. tuberculosis in patients harbouring these organisms. PMID- 4220082 TI - Comparative trials of British BCG vaccine double strength, and Danish BCG vaccine, with standard strength British BCG vaccine. PMID- 4220083 TI - Mycobacterium gadium sp. nov. a new species of rapid-growing scotochromogenic mycobacteria. PMID- 4220084 TI - Congenital anomalies of the lower urinary tract from a radiologic point of view. AB - Congenital anomalies of the lower urinary tract are being recognized with greater frequency due to the use of micturating cystourethrography. Many of these malformations present with urinary tract infection. Early diagnosis is important as appropriate treatment may prevent deterioration of renal function. Several illustrative cases are presented, such as posterior urethral valves, diverticula of the urethra, rectourethral fistula, and duplication of the urethra. PMID- 4220085 TI - Aspartylglycosaminuria: a gargoyle-like syndrome with autosomal recessive inheritance. AB - Aspartylglycosaminuria is an autosomal recessive disorder of glycoprotein catabolism, characterized by presence of aspartyglycosamine in the urine, progressive mental retardation, coarse face, impaired speech and motor functions, and signs of involvement of connective tissue and skeleton. In infancy, clinical symptoms are mild or absent. Vacuolized lymphocytes are often found in the blood and bone marrow. The disease appears unusually common in Finland. PMID- 4220086 TI - [Prevention of post-traumatic epilepsy following serious brain injuries. Closing report summarizing results of the research done within the framework of the state plan of research in the years 1965-1969; edited by Z. Servit]. PMID- 4220087 TI - Ingestion of asbestos. PMID- 4220088 TI - [Morphogenetic consequences of experimental microglossia]. PMID- 4220089 TI - [Convergence of 3 thalamo-cortical rhythmic systems on the somesthetic area in the normal cat and baboon]. PMID- 4220090 TI - [Discordance of the effects of reserpine on the so-called "PGO" spikes in a primate and in the cat]. PMID- 4220091 TI - [Mediterranean lymphoma with alpha heavy chain disease. A Tunisian case]. PMID- 4220092 TI - The toxicity of sodium nitroprusside. PMID- 4220094 TI - [Effects of different lesions of nerves and facial muscles in photosensitive Papio papio]. PMID- 4220093 TI - [EEG polygraphic study of wakefulness and sleep in a syndrome of myoclonus of action and intention]. PMID- 4220095 TI - [Perspectives offered by the statistical study of time occupied by the half-waves of the EEG signal for the qualification and the quantification of physiologic, psychophysiologic and pathologic states]. PMID- 4220096 TI - [Multisensory evoked responses in the baboon with a rolandic epileptic focus]. PMID- 4220097 TI - [Sensory endings of the esophagus in the cat and rhesus monkey]. PMID- 4220098 TI - Local and systemic subarachnoid toxicity of metrizamide in mice and monkeys. PMID- 4220099 TI - Chloroplast- and cytoplasm-specific aminoacyl-transfer ribonucleic acid synthetases of Euglena gracilis: separation, characterization and site of synthesis. PMID- 4220100 TI - Hycanthone: a review of its experimental chemotherapy, pharmacology and toxicology. PMID- 4220102 TI - A study of the feeding and social behaviour of the "Macacus rhesus" monkey after direct electrical stimulation and telestimulation of different points of the amygdala and the hippocampus. AB - We examined first the behavior of a single animal (Macacus Rhesus), partially free to move on a Brady chair, before and after direct electrical stimulation of the amygdala and the hippocampus; then the social behavior of two animals, completely free to move in a large behavioral cage, before and after stimulation, by radio, of the amygdala. Certain ventromedial areas of the amygdala have a short and long term inhibitory effect on feeding and social behavior and the hippocampus has a short and long term facilitating effect on feeding behavior, especially during the after discharge. PMID- 4220101 TI - Retinol-binding proteins. PMID- 4220103 TI - Calcium ions and the function of the contractile proteins of muscle. PMID- 4220104 TI - Calcium movements in relation to contraction. PMID- 4220105 TI - Photosensitive epilepsy in Papio papio. Possible role of cerebellar lesions on facilitation of seizure discharges. PMID- 4220107 TI - Effects of administering cold and warmed tube feedings. PMID- 4220106 TI - Progressive seizure recruitment in subhuman primates and effect of cerebellar stimulation upon developed vs. developing amygdaloid seizures. PMID- 4220108 TI - A physiological and behavioral approach to understanding the mechanisms of obesity and anorexia. PMID- 4220109 TI - Critique of "A physiological and behavioral approach to understanding the mechanisms of obesity and anorexia". PMID- 4220110 TI - [Control of TSH secretion. II. Clinical exploration of the thyrotropin axis]. PMID- 4220111 TI - [How to interpret absence of a response to TRH?]. PMID- 4220112 TI - The effects of oestrogens on the sexual behaviour of the femal rhesus monkey. PMID- 4220113 TI - The effects of oestrogen-treatment of the female on the behaviour of the male rhesus monkey. PMID- 4220114 TI - [Thyrotropin releasing factor and depressive state: acroagonines of TRH]. PMID- 4220115 TI - [Regulation, by feedback, of gonadotropin hormone secretion in rhesus monkeys]. PMID- 4220117 TI - [Parathormone and calcitonin function in aged persons]. PMID- 4220118 TI - [Kinetics of thyroid function in the aged]. PMID- 4220116 TI - [Mechanism of action of TRH (thyrotropin releasing hormone) on anterior hypophyseal cells]. PMID- 4220120 TI - Pathological problems around the placental separation. PMID- 4220119 TI - Oral manifestations of von Reclinghausen's disease: report of a case. PMID- 4220121 TI - The expression of inherited metabolic disease in cultured cells. PMID- 4220122 TI - [Bioassay of metabolic promoting factor in human saliva for acidogenic bacteria (author's transl)]. PMID- 4220123 TI - [A microscopic study of destructive processes in human enamel--the changes in enamel destruction owing to the attack of EDTA (author's transl)]. PMID- 4220124 TI - Characteristics of rat normal mammary epithelial cells and dimethylbenzanthracene induced mammary adenocarcinoma cells grown in monolayer culture. PMID- 4220125 TI - Hodgkin's disease and the non-Hodgkin's lymphomas in childhood. PMID- 4220126 TI - The chemical therapy of breast cancer. PMID- 4220128 TI - Comparative histology of the sustentacular organs in the tongues of the mammalia. PMID- 4220127 TI - Transfer-factor therapy of malignancy. PMID- 4220129 TI - Use of microtiter and agar-gel diffusion techniques in screening avian serums for influenza A and Myxovirus yucaipa antibodies. PMID- 4220130 TI - [Reasons for antibacterial and antiparasitic combinations]. PMID- 4220131 TI - [Taxonomic observations on Streptoverticillium griseocarneum]. AB - A strain of Streptoverticillium (IA-7527) which produces an antibiotic complex formed at least by two substances--one active against fungi and another active against bacteria--has been identified as Stv. griseocarneum. The methods and the results of the International Streptomyces Project were used. By comparing the results obtained, i.e., the description of the sample IA-7527, with ISP standard descriptions of the related species, and attributing percentual values of similarity to each corresponding item, the overall similarity between the strains compared was obtained. The main result of the study is the conclusion that the ISP descriptions of STV. EHIMENSE, Stv. kentuckense, Stv. mashuense, Stv. parvisporogenes, Stv. takataense and Stv. griseocarneum are so similar, that the cited species--and the strain ISP-5464, IMRU 3631, labeled Stv. rubireticuli- should be considered as synonyms of Stv. griseocarneum, the first species described in the group. PMID- 4220133 TI - [Irradiation of intrathoracic tumors using a cesium bomb in an investigation of the relative biological effectiveness of high energy irradiation]. PMID- 4220132 TI - [Griseocarnin, an antifungal antibiotic isolated from Streptoverticillium criseocarneum (IA-7527)]. AB - We have been studying the antagonistic activity of the Streptoverticillium griseocarneum, strain IA-7527. It produces a strong antifungal substance which we named griseocarnin. Its antimicrobial power to Neurospora crassa, Rhodotorula, rubra, Hansenula suaveolens and Candida albicans deserves to be exceled. The isolated substance was compared with other antifungal antibiotics presenting close similarity with the heptaens Ascosin and PA-150. The production, extraction and purification methods as well as physical, chemical and biological properties are included in this work. PMID- 4220134 TI - Prosthodontics in Japan 1973-1974. PMID- 4220135 TI - Oral surgery in Japan 1973-1974. PMID- 4220136 TI - [Corticosteroid therapy in myasthenia gravis: preliminary considerations on the long-term treatment with prednisone]. PMID- 4220137 TI - Pressure-volume curves and closing volume. PMID- 4220139 TI - [Our enemy: The bacillus of tuberculosis]. PMID- 4220140 TI - [Australia antigen, ABO system and RH factor in blood donors]. PMID- 4220141 TI - The rotation of the maxilla. PMID- 4220138 TI - [Comparative study of hyperamylasemia in the early postoperative period]. PMID- 4220142 TI - Long term observation on the extraction of second permanent molars. PMID- 4220143 TI - Milk hygiene and bacteriology in the Sudan: isolation of brucella abortus from cow's milk. PMID- 4220144 TI - Testing acaricide susceptibility of the brown dog tick Rhipicephalus sanguineus (Latreille, 1806). II Teabag method. PMID- 4220146 TI - The vestibular sensory cells and their innervation. PMID- 4220145 TI - A comparative study of vestibulocortical projection. PMID- 4220147 TI - Response patterns of vestibular thalamic neurons in the rhesus monkey. PMID- 4220148 TI - Effects of labyrinthectomy on optokinetic nystagmus (OKN) and optokinetic after nystagmus (OKAN). AB - OKN and OKAN were affected by unilateral and bilateral labyrinthectomy. The maximum velocity of slow phases of OKN induced by drum rotations above 60-75 degrees/sec in either direction was lower after unilateral and bilateral labyrinthectomy. The frequency of OKN was also decreased, and the total deviation of the eyes was reduced for OKN induced by these drum speeds. Changes in OKN eventually recovered. OKAN was reduced in duration after unilateral labyrinthectomy, being initially shorter to the ipsilateral than to the contralateral side. OKAN could no longer be evoked after bilateral labyrinthectomy. This loss was permanent. These data demonstrate the importance of the vestibular system in maintenance of OKN and OKAN. PMID- 4220149 TI - [Endodontic therapy on teeth carrying fixed prosthesis]. PMID- 4220150 TI - [Treatment of diastema between the central maxillary incisors by early excision of the labial frenum]. PMID- 4220151 TI - [The Peutz-Jeghers Syndrome]. PMID- 4220152 TI - [Intraoral radiographic films]. PMID- 4220153 TI - [The biological effects of composite resins]. PMID- 4220154 TI - Experimental study on abnormal habits and malocclusion (part III). PMID- 4220155 TI - [Comparative sensitivity of a KB cell line and monkey kidney cells in primary culture for the titration of live attenuated poliovirus strains (Sabin)]. PMID- 4220156 TI - [Trials of antiseptic media for the preservation of tuberculous sputum during transport. Study in the laboratory and in the field]. PMID- 4220157 TI - Non-hormonal methods of antenatal monitoring. PMID- 4220158 TI - Fetal acid-base balance. PMID- 4220159 TI - The functional occlusion of the teeth of the Vervet monkey. PMID- 4220160 TI - Combination of triamcinolone acetonide and demethylchlortetracycline hydrochloride in the management of pulp hyperemia and acute serous pulpitis. PMID- 4220161 TI - [Stereological studies of vascularization phenomena. 10. Effect of experimental ligation of the left external carotid artery of the crab-eating monkey upon the vasculature of the facial region (author's transl)]. PMID- 4220162 TI - [A study on the morphology of the pulp cavity of the mandibular first molar]. PMID- 4220163 TI - [Basic principles of examination, diagnosis and treatment planning of the oral and dental diseases]. PMID- 4220164 TI - [Minor tooth movement as a part of periodontal therapy]. PMID- 4220165 TI - [Skeletal Class II and Class III deep-bite or open-bite correction with surgical orthodontic management (genioplasty)]. PMID- 4220166 TI - [Porcelain fused to metal]. PMID- 4220167 TI - [Classification and clinical features of periodontal diseases]. PMID- 4220168 TI - [Tissue retraction methods]. PMID- 4220169 TI - [The significance of rubber dam application during dental care. (Two cases of swallowed endodontic instruments)]. PMID- 4220171 TI - Investment bonds for profit. PMID- 4220170 TI - [Biochemical treatment of sequelae of pulp devitalisation for pulpitis]. PMID- 4220172 TI - [Familial progressive myoclonus epilepsy (pme) (type Unverricht)]. PMID- 4220173 TI - [Introduction to the problems discussed in the symposium]. PMID- 4220175 TI - [The necessity of comparative morphology in epilepsy]. PMID- 4220174 TI - [The present status of electroshock therapy in the treatment of mental illnesses]. PMID- 4220176 TI - [The degree of psychic disturbances following bi-and unilateral electroshock therapy as a possible manifestation of brain damage]. PMID- 4220177 TI - [Comparative, morphologic examinations of cardiazol and electroconvulsion in animal experiment]. PMID- 4220178 TI - [Cerebrovascular changes during cardizol and strychnine convulsions]. PMID- 4220179 TI - [Experimental focal cerebral cortex epilepsy]. PMID- 4220180 TI - [The frequency of morphologically demonstrable convulsive damages]. PMID- 4220181 TI - [Observations on succinate and lactate dehydrogenase activity following cardiazol convulsions. (A histochemical study with microdensitometrical evaluation)]. PMID- 4220182 TI - [Epilepsy and hippocampus sclerosis]. PMID- 4220183 TI - [Localized dysplasia of the cerebral cortex based on tissue examinations which were obtained during neurosurgical interventions in epileptics]. PMID- 4220184 TI - [Diffuse leukencephalic fiber gliosis and interface gliosis (Chaslin) in epilepsy]. PMID- 4220185 TI - [Morphological changes of cerebral vessels in progressive forms of epilepsy]. PMID- 4220186 TI - [Forms of progressive myoclonus epilepsy as generalized metabolic disturbances. Clinical-pathological survey]. PMID- 4220187 TI - [Periodontal changes in anterior teeth due to occlusal changes]. PMID- 4220188 TI - [Experimental zygomatic arch resection in the Cebus apella. I. The influence on the masseter muscle and the skull]. PMID- 4220190 TI - [Physiological problems and physiopathological justification of parenteral hyperalimentation]. PMID- 4220189 TI - The healing of extraction wound in the presence of retained root remnants. Clinical, radiographical and histological study. PMID- 4220191 TI - [EB 51 (Trivemil), a complete nutriment for parenteral alimentation]. AB - EB 51 (Trivemil) is an original fat emulsion containing L. aminoacids and glucids in its liquid phase in the following proportions: amino acids: 60 gl/l corresponding to 8,77 g of nitrogen or 250 calories, sorbitol: 100 g/l or 400 calories wheatgerm oil: 38 g/l or 350 calories. This preparation supplies 1000 per liter. Its objective is to furnish simultaneously the amino acids as well as the energy necessary for their anabolism. EB 51 was administered in 43 patients during several days at a dosage of 1000 or 1500 ml. The tolerance of the product was excellent. Its usefulness was appreciated by nitrogen balance studies as well lipid blood tests. The clearing of the plasma in practically all the cases was very good and the nitrogen saved was almost equivalent to the amount furnished. The indications, dosage and contreindications of EB 51 are detailed. PMID- 4220192 TI - [Total parenteral nutrition with mixtures ready for use]. PMID- 4220193 TI - [Nitrogen balance in the early postoperative period after digestive surgery. Influence of caloric and protein intake (exclusive parenteral alimentation)]. PMID- 4220194 TI - [Hypercaloric parenteral nutrition in neurosurgery]. PMID- 4220195 TI - [Biological surveillance of hyperalimentation in prolonged resuscitation]. PMID- 4220196 TI - [Dehydration caused by osmolar overloading in enteral and parenteral artificial feeding]. PMID- 4220197 TI - [Artificial hyperalimentation in resuscitation. Conclusions]. PMID- 4220198 TI - [Subtotal resection of the small intestine in piglets and parenteral nutrition. Preliminary results]. PMID- 4220199 TI - [Nutritional and clinical aspects of intravenous nutrition in burned patients]. PMID- 4220200 TI - [Hyperalimentation and extensive digestive exereses]. PMID- 4220201 TI - [Value of parenteral hyperalimentation (PHA) in the treatment of severe surgical denutrition and, especially, in digestive fistulas. A propos of 7 cases]. PMID- 4220202 TI - [Remarks on the metabolic bases of parenteral nutrition]. PMID- 4220203 TI - [Parenteral nutrition during uremia]. PMID- 4220204 TI - [Protein, caloric, phosphorus and calcium requirements in prolonged exclusive parenteral nutrition in children]. PMID- 4220205 TI - [Total parenteral nutrition in pediatric surgery]. PMID- 4220206 TI - [New technics for long-term parenteral nutrition]. PMID- 4220207 TI - [Parenteral nutrition through an arteriovenous shunt]. PMID- 4220208 TI - [Prolonged intestinal substitution in the dog]. PMID- 4220209 TI - [Parenteral alimentation with or without lipids]. PMID- 4220210 TI - [An illustrated key to Triatominae, transmiters of Chagas' disease in Brazil]. PMID- 4220211 TI - [Chagas' disease in blood donors of the blood bank of the Hospital Pronto Socorro of Recife]. PMID- 4220212 TI - Epidemiology of Chagas' disease in the state of Ceara, Brazil. IV. The role of dogs and cats as domestic reservoir. PMID- 4220213 TI - [Various aspects of the epidemiology and therapy of Chagas' disease in Brazil]. PMID- 4220215 TI - [On the arterial supply to the lower gingiva and the adjacent mucosa of the crab eating monkey (author's transl)]. PMID- 4220214 TI - [Effect on artificially induced root canal decay on periodontal tissues (author's transl)]. PMID- 4220217 TI - [Development of the dental profession]. PMID- 4220216 TI - [On the anti-bacterial effect of some metals]. PMID- 4220218 TI - The animal experimental model ischemic injuries. PMID- 4220219 TI - The localized vasomotor and permeability changes at the site of injury which determine the secondary development of permanent damage: the physical approach (cord cooling). PMID- 4220220 TI - Resuscitation and parenteral nutrition in patients with acute spinal cord injuries and associated injuries. PMID- 4220221 TI - The need for a national policy for the management of inherited metabolic disease. PMID- 4220222 TI - Inborn errors of metabolism. Vitamin-responsive genetic disease. AB - The several ways in which vitamin administration may bring about a biochemical response in genetic abnormalities have been discussed. Two major interrelated lessons emerge from what we now know about vitamin-responsive genetic disease. First, it is possible to enhance metabolite flow through partially deficient reactions by suitable manipulation of the environment in which a fixed amount of enzyme functions or by changing the concentration of the enzyme itself. The latter approach may be the most versatile in the long run since there may be agents other than vitamins which increase enzyme concentrations. A striking example of such an effect in mammals is furnished by the work of Pitot and his collaborators, who by administration of casein hydrolysate to rats, increased threonine dehydratase activity several hundred-fold (Peraino and Pitot, 1964) by increasing the rate of enzyme synthesis (Jost, Khairallah, and Pitot, 1968). Other means of enhancing enzyme activities, ranging from tissue transplantation to transfer of genetic material, have been discussed elsewhere (for example, see Brady, 1973). These procedures will not be discussed here, other than to mention a recent report (Mukherjee and Krasner, 1973) who transferred several small plugs of liver tissue (approximately 5% of the liver) from normal rats to the livers of rats genetically deficient in bilirubin uridine diphosphate glucuronyltransferase activity. Twelve weeks later the specific activity of glucuronyltransferase had risen in the livers of the recipient rats to 6-23% of normal, and the serum bilirubin of these rats, which had initially been elevated, had fallen to close to, or within, the normal range. Thus liver grafts between suitably matched individuals, may in the near future, become a means of increasing hepatic activities of deficient enzymes to extents which are therapeutically meaningful. The second lesson to be learned from the review presented here is that enhancement of enzyme activity may be therapeutically beneficial even though the increase is small and the activity attained is still reduced relative to normal. It will be well to bear this in mind in any attempts to treat inborn errors of metabolism. PMID- 4220224 TI - Focal seizures, early veins, and increased flow. A clinical, angiographic, and radioisotopic correlation. AB - Prominent early draining veins have been found in angiograms of four patients studied during an acute benign illness characterized by repetitive focal motor seizures and prominent postictal neurologic deficits. Concomitant intravenous radionuclide gamma camera flow and static images showed increased relative perfusion with a slight positive static uptake on the involved side. Follow-up studies showed no evidence of these abnormalities. These angiographic and radioisotopic findings probably correlate with the clinically observed cortical hyperemia as part of, or subsequent to, focal motor seizures. Alternatively, these findings suggest the possibility that vascular occlusions may be the underlying cause of the patients' illness. PMID- 4220226 TI - Research support for diagnostic ultrasound. PMID- 4220225 TI - Lafora's disease: peroxisomal storage in skeletal muscle. AB - A 17-year-old patient had myoclonic epilepsy caused by Lafora's disease. Biopsy showed polysaccharide accumulations within membrane-bound spaces in skeletal muscle cells. Some of the accumulations were morphologically similar to Lafora bodies as they have been seen in the brain. The histochemical reactions of these membrane-bound spaces suggested that they were peroxisomes. Polysaccharide accumulations also were demonstrated in hepatic cells, where they probably were located in the endoplasmic reticulum. Lafora's disease can be diagnosed by histochemical and electron microscopic study of skeletal muscle. PMID- 4220227 TI - Ultrasound in the diagnosis of hydronephrosis in infants and children. PMID- 4220228 TI - The sign of the vena cava: echotomographic illustration of right cardiac insufficiency. PMID- 4220229 TI - Quantitative echography--the basis of tissue differentiation. PMID- 4220230 TI - Light-emitting diode device for display of numerical data on any ultrasound oscilloscope. PMID- 4220223 TI - Mucopolysaccharidoses and mucolipidoses. PMID- 4220231 TI - Indications for ultrasonic scanning in abdominal diagnostics. PMID- 4220232 TI - Echocardiographic determinations of dimensions of normal newborns at 5,280 feet elevation. PMID- 4220233 TI - Schlieren study of pulsed ultrasound transmission through human skull. PMID- 4220235 TI - Research support for diagnostic ultrasound. PMID- 4220234 TI - Different standards of presentation used in ultrasound articles. PMID- 4220236 TI - Echocardiographic diagnosis of calcific stenosis of a stented aortic homograft in the mitral position. PMID- 4220237 TI - Ultrasonic B-scanning in rhesus incompatibility. PMID- 4220238 TI - Enhancement of DNA synthesis in neonatal mouse tibial epiphyses after exposure to therapeutic ultrasound. PMID- 4220239 TI - Ultrasound in twin gestation. PMID- 4220240 TI - The validity of structure identification for cross-sectional echocardiography. PMID- 4220241 TI - Transmitted ultrasound for relief of obstruction in ureters and arteries: current status. PMID- 4220243 TI - Ocular neurofibromatosis. PMID- 4220242 TI - Diabetes mellitus in childhood. PMID- 4220244 TI - Effect of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosis. PMID- 4220245 TI - Genetics of atopic allergy and reagin production. PMID- 4220246 TI - Vernal kerato-conjunctivitis: an allergic disease of the eyes of children. PMID- 4220247 TI - Mutation frequency decline following chemical mutagenesis of Salmonella typhimurium. PMID- 4220248 TI - The genetics and cytology of a mutator factor in Drosophila melanogaster. PMID- 4220249 TI - A population approach to the study of repair of genetic radiation damage in mature spermatozoa of Drosophila melanogaster. PMID- 4220250 TI - Mesangiocapillary glomerulonephritis and persistent hypocomplementemia. PMID- 4220251 TI - Delivery of medical care to isolated communities. PMID- 4220252 TI - [Economic considerations in the use of electronic data processing facilities in the field of medicine]. PMID- 4220253 TI - [Economic considerations in electronic data processing]. PMID- 4220254 TI - [Economic considerations of telemetric processing of medical data]. PMID- 4220255 TI - [Real time data collection and processing with a whole body activity counter]. PMID- 4220257 TI - Virology of germfree rodents. PMID- 4220256 TI - [A rare case of ossifying fibroma of the frontal sinus]. PMID- 4220258 TI - Decreased rate of cytolysis of Colpidium striatum by cystic fibrosis serum. I. Bioassay and evidence for the possible involvement of a C/F factor--IgG complex. PMID- 4220259 TI - The effect of bovine growth hormone on growth of mammary tumors in hypophysectomized rats. PMID- 4220260 TI - Antibody production to choline acetyltransferase purified from human brain. PMID- 4220261 TI - Evolution of enzyme replacement therapy for lipid storage diseases. PMID- 4220262 TI - Association of diamine oxidase with microsomal membranes in rabbit liver. PMID- 4220263 TI - Segmental intramural diverticulosis associated with and confined to a spastic area of muscular hypertrophy in a columnar lined oesophagus. PMID- 4220264 TI - A study of serum nerve growth stimulating activity in patients with neurofibromatosis utilizing a modified bioassay technique. PMID- 4220265 TI - Anemia and neutropenia caused by copper deficiency. PMID- 4220266 TI - Hypersensitivity pneumonitis caused by a contaminated cool-mist vaporizer. PMID- 4220267 TI - Specificity and molecular features of an insect attractant in a Drosophila mutant. PMID- 4220269 TI - Genetic transfer of the stable L form state to intact bacterial cells. PMID- 4220270 TI - A family with two siblings affected by Morquio syndrome (MPS IV). Electrophysiological and psychophysical findings in the visual system. PMID- 4220272 TI - Vertigo. PMID- 4220271 TI - Myasthenic response to muscle relaxants in von Recklinghausen's disease. PMID- 4220273 TI - Drug treatment of Meniere's disease. PMID- 4220274 TI - Labyrinthine surgery for Meniere's disease. PMID- 4220275 TI - Vestibular neuronitis. PMID- 4220276 TI - Evaluation of post-traumatic vertigo. PMID- 4220277 TI - Positional vertigo and nystagmus. PMID- 4220278 TI - The diagnosis and evaluation of acoustic neuromas. PMID- 4220279 TI - Labyrinthine tap as a diagnostic test for acoustic neurinoma. PMID- 4220280 TI - Surgery of acoustic tumors. PMID- 4220281 TI - Meniere's disease. Etiology, natural history, and results of treatment. PMID- 4220282 TI - Central vertigo. PMID- 4220283 TI - Basilar-vertebral artery insufficiency as a cause of vertigo. PMID- 4220284 TI - Diagnostic evaluation of the patient presenting with vertigo. PMID- 4220285 TI - The antimotion sickness drugs. PMID- 4220287 TI - Audiologic tests in the differential diagnosis of vertigo. PMID- 4220286 TI - Basic audiometric findings in Meniere's disease. PMID- 4220288 TI - The caloric test and its value in evaluation of the patient with vertigo. PMID- 4220289 TI - Electronystagmography and its value in the diagnosis of vertigo. PMID- 4220291 TI - Breakdown of HB 129, HB 130. PMID- 4220290 TI - Appropriate standard of care. PMID- 4220292 TI - Rx for professional nursing: the Irvis Report. PMID- 4220293 TI - Cost control in the delivery of health care services. PMID- 4220294 TI - Professional nursing and the abortion decisions. PMID- 4220295 TI - Why nurses leave nursing. PMID- 4220296 TI - Conventional radiography of the temporal bone. PMID- 4220297 TI - Tomographic anatomy of the temporal bone. PMID- 4220298 TI - Tomographic evaluation of cholesteatomas of the middle ear and mastoid. PMID- 4220299 TI - Otosclerosis. PMID- 4220300 TI - The diagnosis of acoustic neuromas. PMID- 4220301 TI - Trauma of the ear. PMID- 4220302 TI - Congenital malformations of the ear. PMID- 4220303 TI - Normal radiographic anatomy of the paranasal sinuses. PMID- 4220304 TI - Inflammatory diseases of the paranasal sinuses. PMID- 4220305 TI - Fractures of the paranasal sinuses. PMID- 4220306 TI - Cysts, benign tumors, and malignant tumors of the paranasal sinuses. PMID- 4220307 TI - Sialography and the salivary glands. PMID- 4220309 TI - Radiology of the larynx. PMID- 4220308 TI - The temporomandibular joint. PMID- 4220310 TI - Radiological studies of the lymphatic system of the head and neck. PMID- 4220311 TI - Bronchography. PMID- 4220312 TI - Anatomy of the nasal cavities. PMID- 4220313 TI - Physiology of the nose. PMID- 4220314 TI - Olfaction. PMID- 4220315 TI - The nasal vasomotor reaction. PMID- 4220316 TI - The "stuffy" nose. PMID- 4220317 TI - Submucous operations on the nasal septum. PMID- 4220318 TI - Nasal septoplasty. PMID- 4220319 TI - Septal perforations. PMID- 4220320 TI - Minor intranasal procedures. PMID- 4220321 TI - Nasal Hemorrhage. PMID- 4220322 TI - Septal dermoplasty for hereditary telangiectasia and other conditions. PMID- 4220323 TI - Cerebrospinal fluid rhinorrhea. PMID- 4220324 TI - Atrophic rhinitis. PMID- 4220325 TI - Choanal atresia. PMID- 4220327 TI - Neoplasms of the nasal cavity. PMID- 4220326 TI - Nasal fistulas. PMID- 4220329 TI - Rhinomanometry. PMID- 4220328 TI - Unusual nasal tumors. Problems in diagnosis and treatment. PMID- 4220330 TI - A public concern--a study of the provision of denture services in the delivery of dental health care in Ontario. PMID- 4220331 TI - [Ultrastructural aspects of gingivitis. Chronic gingival fibers]. PMID- 4220332 TI - [A new green disclosing agent for dental plaque]. PMID- 4220333 TI - [Surgical dressings after oral surgery. Yes or no?]. PMID- 4220334 TI - [Prevalence of geographic tongue, fissured tongue, hairy tongue and median rhomboid glossitis in school children from San Paulo]. PMID- 4220335 TI - [Silicate cements. Comparative study of the percentage of disintegration with phosphate. II. Analysis of correlation]. PMID- 4220336 TI - [Stereophotogrammetric study of the cuspal inclines of mandibular bicuspids regarding dental occlusion]. PMID- 4220337 TI - [Rugosimetric evaluation on the proximal aspect of specimens prepared with four brands of silver alloy]. PMID- 4220338 TI - [Influence of different mixing spatulas on silicate cement color]. PMID- 4220339 TI - [Experimental hypothyroidism in rats. Study at the periodontal level]. PMID- 4220340 TI - [Epidemiology of dental disease. Basic methods of the World Health Organization]. PMID- 4220341 TI - [Contribution to the nasal index of Brazilians]. PMID- 4220342 TI - [Craniometric study in Pakatege Indian tribe (Hawks) from Je group]. PMID- 4220343 TI - [Studies on the organic matrix of calcified tissues. I. Chromatographic demonstration of amino acids, in human pre-historic bones and teeth]. PMID- 4220344 TI - [Pulpal and dentinal response to self-threaded and hand-threaded retention pins]. PMID- 4220345 TI - [Zinc polycarboxylate cements. Their use with different dental alloys]. PMID- 4220346 TI - [Burkitt's lymphoma. Review of the literature, clinical aspects and report of case in a child from Sao Paulo]. PMID- 4220347 TI - [Human relations in the dental clinic]. PMID- 4220348 TI - Cholinergic mechanisms in aggressive behaviour. PMID- 4220349 TI - Monohydroxy bile acids in plasma in intrahepatic cholestasis of pregnancy. Identification by computerized gas chromatography-mass spectrometry. PMID- 4220350 TI - Effect of ventromedial tegmental lesions on central catecholamine neurons of monkey brain: involvement of dopamine pathways in tremor and involuntary movements. PMID- 4220351 TI - Energy and protein requirements. Report of a joint FAO/WHO ad hoc expert committee. Rome, 22 March-2 April 1971. PMID- 4220352 TI - Toxicological evaluation of some enzymes, modified starches and certain other substances. Joint FAO/WHO Expert Committee on Food Additives. PMID- 4220353 TI - Some aspects of prognosis after severe head injury. PMID- 4220354 TI - Rehabilitation in severe head injuries. PMID- 4220355 TI - Controlled ventilation in the management of patients with severe head injuries. PMID- 4220356 TI - Translational versus rotational acceleration: animal experiments with measured input. PMID- 4220357 TI - Hydrocephalus following traumatic head injuries. PMID- 4220358 TI - Evaluation of mental disturbances after head injury. PMID- 4220359 TI - Cardiac conditioning and extinction in Macaca mulatta during block of the CR by cardiac pacing. PMID- 4220360 TI - Psychopharmacologic facilitation of operant conditioning of genetically nervous catahoula and pointer dogs. PMID- 4220361 TI - CS intensity effects on rabbit nictitating membrane conditioning, extinction and generalization. PMID- 4220362 TI - Inability to condition a peripheral activating drug. PMID- 4220363 TI - Procedure for operant conditioning of the dog. PMID- 4220364 TI - Hypothesis on the significance of RNA-directed DNA synthesis for evolution. PMID- 4220365 TI - The effect of tranylcypromine (parnate) on eyelid conditioning and paired associate learning in depressed patients. PMID- 4220366 TI - Emotions and cardiac contractility as reflected in ballistocardiographic recordings. PMID- 4220367 TI - The rehabilitation of genetically nervous dogs. PMID- 4220368 TI - Long-term conditioned fear modification in the dog as measured by changes in urinary 11-hydroxycorticosteroids, heart rate and behavior. PMID- 4220371 TI - The probation officer. Part II. PMID- 4220370 TI - A group practice approach to sex education. PMID- 4220369 TI - The effect of change in US quality on the blocking effect. PMID- 4220372 TI - A survey of symptoms occurring in pregnancy. PMID- 4220374 TI - Vasectomy. Sounding a note of concern. PMID- 4220375 TI - Vasectomy. From a patient's viewpoint. PMID- 4220373 TI - Vasectomy. Safe, simple and trouble-free. PMID- 4220376 TI - The sexual problems of doctors. PMID- 4220377 TI - Studies on the intestinal actions of tyramine. PMID- 4220378 TI - Altered development of central noradrenaline neurons during ontogeny by 6 hydroxydopamine. PMID- 4220380 TI - Observations on the concept of neighbourhood knowledge and the distribution of marriage distances. PMID- 4220379 TI - Genetic markers in chronic myelocytic leukaemia: evidence opposing autosomal inactivation and favouring 6-PGD-Rh linkage. PMID- 4220381 TI - Studies of the density and the properties of the hair in a new inherited syndrome of hypotrichosis. PMID- 4220383 TI - [Bottle feeding of newborn infants]. PMID- 4220385 TI - Current trends in infant feeding. PMID- 4220384 TI - Clinical value of nerve conduction studies. PMID- 4220386 TI - [Advocating of breast feeding--maternal awareness and factors affecting the choice]. PMID- 4220387 TI - Clinical research in cleft lip and cleft palate: the state of the art. PMID- 4220388 TI - Paediatric nursing: the crying child. PMID- 4220389 TI - Mother's milk and other home foods. PMID- 4220390 TI - [Nutritional health for infants in the family. I]. PMID- 4220391 TI - Nutrition programs in state health agencies. PMID- 4220392 TI - [Assay of a self teaching nodule in pediatrics]. PMID- 4220393 TI - The effect of early feeding on the development of obesity. PMID- 4220395 TI - Food for the growing brain. PMID- 4220394 TI - [Lengede-ten years after. Medicopsychological catamnesis of an extreme strain situation]. PMID- 4220396 TI - [Child rearing and development of various personality traces in the traditional Turkish society]. PMID- 4220397 TI - The evaluation of prison treatment and preventive detention programs: some problems faced by the Patuxent institution. PMID- 4220399 TI - Variations in hormone concentrations in bovine sera used for tissue culture. PMID- 4220398 TI - Lysinuric protein intolerance. AB - Lysinuric protein intolerance is an autosomal recessive disorder which first appears as failure to thrive, vomiting and diarrhea in the infant after weaning from mother's milk. Later it manifests as failure to grow, muscular weakness and osteopenia associated with aversion to animal protein. Some patients become mentally retarded and have periods of stupor. The disease is characterized by marked lysinuria, and hyperammonemia after protein intake. According to accumulating evidence, the basic defect is deficient transport of diamino acids in the intestine, liver and kidney tubuli. Effective treatment is provided by supplementing protein food with extra arginine. PMID- 4220400 TI - [Camp for handicapped children on the Baltic coast]. PMID- 4220402 TI - Building standards for the handicapped. PMID- 4220403 TI - The cause and treatment of low back pain during pregnancy. PMID- 4220404 TI - An ounce of prevention: the Division of Dental Health. PMID- 4220401 TI - [Studies on the acid mucopolysaccharides of hog gastric mucin (II)]. PMID- 4220405 TI - [On the treatment of polygenetic rosacca with Medivitan]. PMID- 4220406 TI - Maternal dehydroepiandrosterone and estrogen production in late pregnancy. PMID- 4220407 TI - [A simple method for the treatment of median abdominal cicatricial hernia]. PMID- 4220408 TI - The haemolytic uraemic syndrome. PMID- 4220409 TI - Lactic dehydrogenase levels in pernicious anemia. PMID- 4220410 TI - The immediate care of thoracic injuries. PMID- 4220411 TI - Primary malignant tumors of the retroperitoneum. PMID- 4220412 TI - Progress in medicine--a look ahead. PMID- 4220413 TI - Neurologic manifestations of electrical injury. PMID- 4220414 TI - Treatment of allergy in children: a double-blind study. PMID- 4220415 TI - [Lolium (sailam) in an Arabic magic prescription]. PMID- 4220416 TI - The Hippocratic Treatise Peri diaites oxeon. PMID- 4220417 TI - Dates in the printed editions of the Lilium Medicinae. PMID- 4220418 TI - [Labor disability insurance, joint medical service and rehabilitation. Less manpower--more action]. PMID- 4220419 TI - [Experience with 200 laparoscopies]. PMID- 4220420 TI - [Follow-up examination of amubulant patients treated for lumbago by manipulation]. PMID- 4220422 TI - [Physical defects and school career. Mens sana in corpore sano]. PMID- 4220421 TI - [A new antibiotic active against gonorrhea]. PMID- 4220423 TI - Cystic acne of infancy. PMID- 4220424 TI - Follicular mucinosis (alopecia mucinosa). PMID- 4220425 TI - Intracellular enzyme changes in post-anoxic rat brain. PMID- 4220427 TI - A cooling modification to an apparatus for phage typing of Staphylococcus aureus. PMID- 4220426 TI - The antigenicity in man of staphlylococcal leucocidin toxoid, with notes on therapeutic immunization in chronic osteomyelits. PMID- 4220428 TI - Studies on the role of sulfhydryl groups in the biochemical mechanisms of allergic inflammation. 8. Influence of glutathione reductase on reactivation of Arthus-type inflammation by glutathione. PMID- 4220429 TI - [Value and significance of recent acquisitions on physiology of neuromuscular spindles in relation to some neurologic and psychophysiologic problems]. PMID- 4220430 TI - [Characteristics of the spindles during sleep in chorea patients]. PMID- 4220431 TI - Autosomal mosaicism occurring in conjunction with Down's syndrome. PMID- 4220432 TI - The sibships posterior to mongoloids. PMID- 4220433 TI - [Obstetric care in the 9th Health Subdistrict, Mexico, D. F]. PMID- 4220434 TI - [Comments on fluoridation of the public water supply]. PMID- 4220435 TI - [Fluoridation of water as a public health measure]. PMID- 4220436 TI - [Engineering aspects of the fluoridation of water]. PMID- 4220437 TI - [Fluoridation of drinking water in Chile]. PMID- 4220439 TI - "A little child shall lead them". PMID- 4220438 TI - [Hygienic standards for water used for recreational purposes]. PMID- 4220441 TI - An investment for the future. PMID- 4220442 TI - Are you just a dentist? PMID- 4220440 TI - The first appointment--a mutual evaluation session. PMID- 4220443 TI - An evaluation of the efficacy of hydroxyzine (atarax-vistaril) in controlling the behavior of child patients. PMID- 4220444 TI - Permanent tooth eruption in children with major physical defect and disease. PMID- 4220446 TI - The problem of P.T.B. aggravation in compensation cases . PMID- 4220445 TI - A simplified radiographic technique for the difficult patient. PMID- 4220447 TI - Acne vulgaris. PMID- 4220448 TI - The angiogram and pulmonary artery structure and branching (in the normal and with reference to disease). PMID- 4220449 TI - [Pedodontics and the current concepts of deciduous tooth extractions]. PMID- 4220450 TI - [Familial occurrence of dysostosis enchondralis]. PMID- 4220451 TI - [Biological bases for bone transplantation]. PMID- 4220452 TI - [Electromyographic contribution to the problem of scoliosis]. PMID- 4220453 TI - [Diagnosis of sacral nerve root cysts and their clinical significance]. PMID- 4220454 TI - [Studies on the heredity of the curvature of the sacrum]. PMID- 4220455 TI - [Further observations on senile ankylosing spinal hyperostosis (Forestier and Rotes)]. PMID- 4220457 TI - [On the problem of the surgical correction of the femoral neck angle in derotation osteotomy in hip dislocation]. PMID- 4220456 TI - [On the healing course of Calve's vertebra plana]. PMID- 4220458 TI - [The conservative phase in hand surgery including tendon injury]. PMID- 4220460 TI - [A small vertebra causing prespondylolisthesis]. PMID- 4220459 TI - [Incidence of dysmelia in the former Hannover Province in the years 1920-1963]. PMID- 4220461 TI - [Concordance of the 5th lumbar vertebra in twins]. PMID- 4220462 TI - [Subcutaneous rupture of the Achilles tendon in female athletes]. PMID- 4220463 TI - [Current status and requirements of orthopedic education and training in Germany]. PMID- 4220464 TI - [Orthopedics at the cross-road?]. PMID- 4220465 TI - The skin of primates. XXVI. Specific and nonspecific phosphatases in the skin of the rhesus monkey. PMID- 4220466 TI - Plasmin and plasminogen levels in pregnancy. PMID- 4220467 TI - [Occurrence of acne vulgaris after copious intake of beer]. PMID- 4220468 TI - Genetic analysis of T4D phage heterozygotes produced in the presence of 5 fluorodeoxyuridine. PMID- 4220469 TI - Sickle-cell anaemia in an Indian family in Johore. PMID- 4220470 TI - Haemoglobin E--thalassaemia in Kelantan. PMID- 4220472 TI - A review of virus infections of the respiratory tract. PMID- 4220471 TI - Agglutinins in normal sera for the typhoid-paratyphoid group of organism. PMID- 4220473 TI - The clinical features, management and treatment of El Tor cholera. PMID- 4220475 TI - A case of renal tubular rickets with absorption defect of glucose and phosphorus. PMID- 4220474 TI - Nocardia asteroides in Malaya. PMID- 4220476 TI - Interdepartmental Committee on Nutrition for National Defence report. Federation of Malaya nutrition survey September--October 1962. PMID- 4220477 TI - Sir Richard Brunel Hawes. PMID- 4220479 TI - When do we do a breast biopsy? PMID- 4220478 TI - [Histochemical observations on the mucopolysaccharide content of the linqual gland of the cat]. PMID- 4220480 TI - Carcinoma of the cervix in Indian women. PMID- 4220481 TI - Practical aspects of blood coagulation. PMID- 4220482 TI - Evacuant suppositories in postpartum care. PMID- 4220483 TI - Neurologic manifestations of injury by ionizing radiation. PMID- 4220484 TI - Social class and reaction to physical disability. PMID- 4220485 TI - Child development projects. PMID- 4220486 TI - Planning for their future. PMID- 4220487 TI - The factory day at school. PMID- 4220488 TI - [Presence of a neutral mucopolysaccharide in the acrosome of the spermatozoid of Glossiphonia complanata(L). (Hirudinea, Rhynchobdellida)]. PMID- 4220489 TI - [Contribution to the study of mucopolysaccharides in renal tuberculosis]. PMID- 4220490 TI - Delayed ontogenesis in human trisomy syndromes. PMID- 4220492 TI - The cost of public health programs in the Philippines. PMID- 4220491 TI - [On the effects of oligo-N-methylmorpholinium propylene oxide on hyaline cartilage in vivo]. PMID- 4220493 TI - An experimental biologic approach to the treatment of neoplastic disease; determination of actinomycin in urine and cultures as an aid to diagnosis and prognosis. PMID- 4220494 TI - Mass screening for diabetes using a skin-surface test. PMID- 4220495 TI - The role of women physicians in disaster medicine. PMID- 4220496 TI - Some unusual features in a case of traumatic rupture of the thoracic aorta. PMID- 4220497 TI - [Therapeutic possibilities in arthrotic and periarthritic processes with acid mucopolysaccharides]. PMID- 4220498 TI - Orthodontic care for children in general practice. PMID- 4220499 TI - [Comparative studies on the histologic detection of sulfomucopolysaccharides]. PMID- 4220500 TI - [A problem of occupational dermatology: elimination of the "soap" effect and protection against nickel sulfate]. PMID- 4220501 TI - Reactions to nalidixic acid. PMID- 4220502 TI - Barriers in dental practice--architectural and structural. PMID- 4220503 TI - [The role of gastric juice mucopolysaccharides in the formation of the blood lipid picture. 1. Correlation between the gastric juice and serum mucopolysaccharide content and blood lipid values in healthy subjects]. PMID- 4220504 TI - [Paracelsus in Croatia]. PMID- 4220505 TI - [Albert Friedrich Schill and general pathology before the era of genetic cell theory]. PMID- 4220506 TI - [Principles of Paracelsus' drug therapy]. PMID- 4220507 TI - [Which plant did Paracelsus mean by brassatella?]. PMID- 4220508 TI - Phage type and antibiotic sensitivity of staphylococci isolated from monkeys and their human handlers. PMID- 4220509 TI - [Acne vulgaris and its treatment]. PMID- 4220510 TI - Effect of tetracycline on the composition of sebum in acne vulgaris. PMID- 4220511 TI - Pathologic coronary vessels and regional systolic narrowing of the coronary arteries in hypertrophic obstructive cardiomyopathy. PMID- 4220512 TI - Tooth ring analysis in mongolism. PMID- 4220513 TI - Sedation in dentistry for children: narcotic action. PMID- 4220514 TI - Cardiomyopathies in children in the tropics. PMID- 4220515 TI - Fibrinolytic activity and fibrinogen levels in Papuans and New Guineans. PMID- 4220516 TI - Health survey on a rural Malay population F.L.D.A., Sungai Tekam, Pahang. PMID- 4220517 TI - Another periauricular abscess from Sarawak, probably caused by a trematode of the genus Poikilorchis, Fain and Vandepitte. PMID- 4220518 TI - [The treatment of dysbiotic intestinal disorders with Mexaform S]. PMID- 4220519 TI - [Mental disorders and simple pilous virilism]. PMID- 4220520 TI - Chondroitin sulfate: inhibition of synthesis by puromycin. AB - Puromycin reversibly inhibits synthesis of chondroitin sulfate by vertebral chondrocytes from 10-day-old chick embryos. Treatment of these cells with puromycin for 5 hours does not affect viability or capacity to multiply on subsequent release from their matrix. It is suggested that synthesis of this polysaccharide is coupled with that of protein; there may be a feedback control in its synthesis. PMID- 4220522 TI - Myocardial free nucleotides in cardiac hypertrophy. PMID- 4220521 TI - [On the therapy of preovulatory and premenstrual acne vulgaris]. PMID- 4220523 TI - Adenosinetriphosphatase (ATPase) in the auricular heart muscle in human patients operated upon because of acquired and congenital cardiac defects. PMID- 4220524 TI - Glycoside-sensitive ATPase from Arachis hypogaea. PMID- 4220525 TI - [Hematoma due to "spontaneous" rupture of the rectus abdominis muscle]. PMID- 4220526 TI - Treatment of recurrent furunculosis with staphylococcal bacteriophage-lysed vaccine. PMID- 4220527 TI - Acne, today. PMID- 4220528 TI - [On Mexaform therapy in pediatrics]. PMID- 4220529 TI - [Functional anatomy of the locomotion process. (Eletromyographic studies during walking)]. PMID- 4220531 TI - [Clinical and roentgenologic results of meniscotomy]. PMID- 4220530 TI - [Our experiences in the surgical treatment of stiffening of the knee joint]. PMID- 4220532 TI - [Femoral fractures in hips following arthrodesis]. PMID- 4220533 TI - [Report on further experiences in the treatment of coxarthrosis with Voss' suspended hip method]. PMID- 4220534 TI - [Contribution to the clinical picture of stiffness of the hip associated with idiopathic protrusion of the acetabulum during puberty]. PMID- 4220535 TI - [Spinal changes in abnormal fragility of the bones]. PMID- 4220536 TI - [On the problem of spinal block]. PMID- 4220537 TI - [Hypernephroma--hypernephroid carcinoma]. PMID- 4220538 TI - [Elephantiasis of the extremities; clinical picture and treatment with special reference to filariasis]. PMID- 4220539 TI - [A new water-resistant walking appliance for lame legs]. PMID- 4220541 TI - Contact dermatitis due to poison ivy, oak, and sumac. PMID- 4220540 TI - [Treatment of protracted Kohler II. disease using osteotomy]. PMID- 4220542 TI - Chronic heart disease due to obesity. PMID- 4220543 TI - The case of Bill Bum, the burbling bursitic. PMID- 4220544 TI - Medical care of compensation cases in Indiana. PMID- 4220545 TI - [The possibilities of treatment of mongolism]. PMID- 4220546 TI - [Compensation for neuritic disorders and sympathetic disorders associated with the sequelae of injuries]. PMID- 4220547 TI - The forgotten patient: medical management of the multiple handicapped retarded. PMID- 4220548 TI - [Contact eczema from triazine in the manufacture of movie and micro film]. PMID- 4220549 TI - This week's offer. PMID- 4220550 TI - How to drill kids without actually shooting them. PMID- 4220551 TI - Management of children under general anesthesia. PMID- 4220552 TI - Financial implications of leprosy and tuberculosis control in Thailand. PMID- 4220553 TI - Evasion of responsibility by physicians in planning health services. PMID- 4220554 TI - A physiological basis for the surgical management of peptic ulceration. PMID- 4220555 TI - Social reality: a necessary dimension to program. PMID- 4220557 TI - Placenta accreta. PMID- 4220556 TI - Significant legislation passed during the 1965 session of the Arkansas legislature. PMID- 4220558 TI - Multiple causality in psychiatric illness and personality formation. Experimental causation of deviant behavior. PMID- 4220559 TI - Resurgence of syphilis. PMID- 4220560 TI - [Topics in infantile electrocardiography. I. Auricular hypertrophy]. PMID- 4220561 TI - Effects of freezing on the stability of staphylococcal phages. PMID- 4220562 TI - Streptomycin sensitization. PMID- 4220563 TI - Spotlighting advances in special education. PMID- 4220564 TI - [Complications of acute leukemia in childhood treated with steroids and cytostatics]. PMID- 4220565 TI - The relation of acid mucopolysaccharides and sulfhydryl groups to diseased oral mucosa. PMID- 4220566 TI - [The new stomatologic department of the municipal hospital of Verona]. PMID- 4220567 TI - [Statistical studies on the depth of the acetabulum]. PMID- 4220568 TI - Enzymatic effects of fibrinolysin. PMID- 4220569 TI - Fibrinogenolytic dysfibrinogenemias. PMID- 4220570 TI - Clearance of infused fibrin. PMID- 4220571 TI - [Current perspectives concerning medical professional secrecy in the Armed Forces]. PMID- 4220572 TI - [Human diploid cells]. PMID- 4220573 TI - [Fatigue and training of military parachutists]. PMID- 4220574 TI - [Diagnosis of ocular hypotension]. PMID- 4220575 TI - [Variations of visual functions with age in flying personnel]. PMID- 4220576 TI - [Bibliographic documentation on the use of lasers in biology and medicine]. PMID- 4220577 TI - Functions of the cancer cell. PMID- 4220578 TI - [Effect of ozone upon mouse ascites tumor cells and upon chick fibroblasts in tissue culture]. PMID- 4220579 TI - [Studies of the reciprocal effect between aromatic hydrocarbons and amines with desoxyribonucleic acid]. PMID- 4220580 TI - [Experimental investigation of "syncarcinogenesis". 4. Studies of the induction of cancer in rats with the simultaneous oral administration of diethylnitrosamine and 4-dimethylaminostilbene]. PMID- 4220581 TI - [Experimental investigations of the metastasis of Yoshida sarcoma]. PMID- 4220582 TI - [The transplacental action of the carcinogen diethylnitrosamine in the mouse]. PMID- 4220584 TI - [Constancy of the chromosomal pattern of tumor cells of a plasmocytoma in the golden hamster]. PMID- 4220583 TI - [The effect of blood serum from tumor patients on organ explants]. PMID- 4220585 TI - [On the active principles of croton oil. IV. Purification and characterization of the irritant and cocarcinogenic compounds B1 and B2]. PMID- 4220586 TI - On the active principles of croton oil. V. Purification and characterisation of further irritant and cocarcinogenic compounds of the B-group. PMID- 4220587 TI - [Cytogenic and karyological studies of clinically treated gynecological tumors]. PMID- 4220588 TI - Staphylococcal infection in the mouse. 3. The effect of survival in infected animals on the mouse virulence of staphylococci. PMID- 4220589 TI - [Idiopathic familial cardiomegaly with intermitten gastrointestinal protein loss. Additional report on the further development and patho-anatomical findings in one of 2 patients]. PMID- 4220590 TI - Surgical correction of inverted nipples. PMID- 4220591 TI - Breast feeding in today's world. PMID- 4220592 TI - Mammography in the diagnosis of breast cancer. PMID- 4220593 TI - Reduction mammaplasty with preservation of nipple-glandular continuity. PMID- 4220594 TI - Plastic reconstruction of the small breast. PMID- 4220596 TI - Breast feeding and breast disease. PMID- 4220597 TI - Changing patterns in education of women. PMID- 4220595 TI - Spinal cord compression secondary to metastatic mammary carcinoma. PMID- 4220598 TI - [Calcified dracunculosis]. PMID- 4220599 TI - [Experimental pulmonary embolisms treated with fibrinolysin and epsilon aminocaproic acid]. PMID- 4220600 TI - [Transposition of the musculoaponeurotic system of the tensor fasciae latae in the repair of the anterolateral abdominal wall in its lower sector, conditioned by the excision of desmoid tumors]. PMID- 4220601 TI - [Abdominal desmoid fibromas. (7 cases)]. PMID- 4220602 TI - [Desmoid tumors of the abdominal wall]. PMID- 4220603 TI - [On the usefulness of latex fixation tests in inflammatory, degenerative and metabolic spine and joint diseases]. PMID- 4220604 TI - [A contribution to the biochemistry of eggshell formation. 2. On the mucopolysaccharides of the eggshell]. PMID- 4220605 TI - "In vitro" biosynthesis of androgens by rat submaxillary glands. PMID- 4220606 TI - Electrocardiographic P wave and atrial weights and volumes. PMID- 4220607 TI - [Ichthyosis and Huntington's disease; heredodegenerations with various heredity in 1 family]. PMID- 4220608 TI - Electromyographic studies on reflex activity of the intercostal and abdominal muscles in cervical cord lesions. PMID- 4220609 TI - [Beta-lipoproteins and their physiological relationship to cholesterol and phospholipid in serum]. PMID- 4220610 TI - A uronic and sialic acid free chick allantoic mucopolysaccharide sulphate which combines with influenza virus hi-antibody to host material. 1. Purification of the substance. PMID- 4220611 TI - Accessory lobe of liver presenting through a congenital deficiency of anterior abdominal wall. PMID- 4220612 TI - [Relationship between the potassium content of erythrocytes of some animal species and the sodium and potassium dependent adenosine triphosphatase activity of the red blood cells]. PMID- 4220613 TI - Studies on fibrinogen fractions isolated from human plasma by precipitation with cold ether. I. Plasma kinin formation by the activation of contained plasminogen. PMID- 4220614 TI - [Desensitization in cement workers' dermatitis]. PMID- 4220615 TI - [Methods of histochemical differentiation of acid mucopolysaccharides]. PMID- 4220616 TI - [Deutscher Ausschuss fur Jugendzahnpflege]. PMID- 4220617 TI - [Metabolism and metabolic reaction following the infusion of dehydro epiandrosterone-phosphate in breast cancer and mastopathies. 3. Behavior of estrogens]. PMID- 4220619 TI - [Disease and its social aspects]. PMID- 4220618 TI - Rupture of the rectus abdominis. PMID- 4220620 TI - Learning problems of handicapped children. PMID- 4220621 TI - [The importance, development and compensation of occupational dermatoses]. PMID- 4220622 TI - The ITPA and Down's syndrome: an exploratory study. PMID- 4220623 TI - Dietary and nutritional problems of crippled children in five rural counties of North Carolina. PMID- 4220625 TI - Transduction of drug-resistances in Staphylococcus. II. Transduction of chloramphenicol-resistance in both Staphylococcus aureus and Staphylococcus epidermidis by typing phage 80. PMID- 4220624 TI - [The muscularity of the left heart ventricle]. PMID- 4220627 TI - Acne vulgaris. Review of one hundred cases. PMID- 4220626 TI - [The sodium and potassium-stimulated adenosine triphosphatase. 4. Action of deoxycholate]. PMID- 4220628 TI - Treatment of acne. PMID- 4220629 TI - Treatment of psoriasis, lichen planus, and seborrheic dermatitis. PMID- 4220630 TI - Treatment of drug eruptions. PMID- 4220631 TI - A model of local fibrinolysis (marked elevation of fibrinolytic activity of blood obtained from vasa efferentia of the uterus). PMID- 4220632 TI - The metabolism of dehydroepiandrosterone in various organs of the rat. PMID- 4220634 TI - Muscle metabolism as seen in single-twitch experiments. PMID- 4220633 TI - Studies on testosterone metabolism. IV. Urinary 5-alpha- and beta-androstanediols and testosterone glucuronide from testosterone and dehydrolsoandrosterone sulfate in normal people and hirsute women. PMID- 4220635 TI - Basic aspects of muscle contraction. PMID- 4220636 TI - [On the "gynecovertebral syndrome"]. PMID- 4220637 TI - [Proteolysis and delayed allergy]. PMID- 4220639 TI - A case of Norwegian scabies. PMID- 4220638 TI - Abdominal muscle involvement during the performance of various forms of sit-up exercise. An electromyographic study. PMID- 4220640 TI - Industrial rehabilitation. PMID- 4220641 TI - Staphylococcal "lysates" and vaccines. PMID- 4220642 TI - Cement dermatitis. II. Clinical aspects. PMID- 4220643 TI - Antimony spots. PMID- 4220645 TI - Serum fractions inhibitory to the growth of Leptospires. AB - It is known that the growth inhibitory substance of animal sera on Leptospires exists in the albumin fraction. Since the globulin fraction obtained from animal sera having growth inhibitory property may support, though variable individually, some degree of leptospiral growth, it may be added, with 5% of pooled rabbit serum, to the medium to be used for the propagation of Leptospires. PMID- 4220646 TI - Effect of injectable iron-dextran on dairy calves and lambs. AB - Ten Holstein calves, 10 Jersey calves, 7 single lambs, and one lamb from each of ten sets of twins were injected with an iron-dextran solution shortly after birth. These were paired with an equal number of untreated animals that formed the control groups. Percentage of hemoglobin and body weights were recorded periodically up to 16 weeks of age for the calves and 21 weeks for the lambs. Percentage of hemoglobin in the blood of treated calves was generally higher than that of untreated calves but body weights between groups were not significantly different. In the lambs there was no significant difference in percentage of hemoglobin or body weights between the treated and control groups. The results indicate that under the confined system of management as outlined, there was no advantage in administering iron-dextran to young calves or lambs. PMID- 4220644 TI - [Hepatic steatosis and cholesterolemia in the domestic duckling in the course of protein malnutrition on a rice diet]. AB - The object of this experiment was to study the influence of essential amino acids on the growth, fatty infiltration of liver and cholesterol level of the serum in ducklings.A 11 per cent protein basal diet, deficient in many essential amino acids, given to ducklings, resulted in poor growth, fatty infiltration of liver and high cholesterol level of the serum. In our experimental design, three amino acids, lysine, methionine and threonine were promoting growth whereas lysine and threonine were preventing fatty infiltration of liver but methionine failed to do so. Rather than a deficiency in lysine alone, simultaneous deficiencies in valine, arginine and lysine resulted in better growth for ducklings. This protective effect of deficiency in valine and arginine together with one in lysine was not effective against fatty infiltration of liver.The cholesterolemia found for the ducklings given basal diet or diets with deficiency in many essential amino acids was higher than that found for the ducklings given diets without essential amino acids deficiency. PMID- 4220647 TI - A study of Toxoplasma infection in chickens and cats on a family farm. AB - Presumptive evidence of toxoplasmosis was obtained following histological and serological studies of tissues from chickens and cats kept on a family farm. This was confirmed by transmission of the infection to experimental laboratory animals and back to chickens. The significance of the low grade serological reaction in one of the persons living on the farm was not clear. PMID- 4220648 TI - Phage patterns of coagulase-positive Staphylococci isolated from dogs. AB - One hundred and thirty-seven coagulase-positive strains of Staphylococcus aureus, isolated from dogs, were tested against three synthetic penicillins (cloxacillin, dicloxacillin, and ampicillin) and also phage typed using bacteriophages which are employed in typing staphylococci isolated from man. PMID- 4220649 TI - Recommended criteria for cardiac catheterization in patients with aortic valve disease. AB - Criteria for selection of patients with aortic valve disease for cardiac catheterization are described, based on a study of 81 cases. Children with aortic stenosis warrant catheterization at the time when the clinical diagnosis is made, but in adults this examination may be deferred until symptoms appear or left ventricular hypertrophy is recognized. In patients with pure aortic insufficiency catheterization may be deferred until symptoms appear. When severe stenosis and insufficiency co-exist, the valve is usually heavily calcified. Thirty-seven per cent of patients with aortic valve disease have co-existing mitral lesions and these patients are usually women, are fibrillating and, as a rule, have atrial enlargement in contrast to those with aortic valve disease only. On rare occasions, patients with mitral valve disease have clinically silent but angiographically demonstrable aortic insufficiency; therefore, aortography should precede open-heart correction of a mitral lesion so as to detect minor degrees of aortic insufficiency. PMID- 4220650 TI - Epilepsy and the law. PMID- 4220651 TI - Elementary and Secondary Education Act: implications for handicapped children. PMID- 4220652 TI - The federal program in the preparation of professional personnel in the education of handicapped children and youth. PMID- 4220654 TI - Research and demonstration program for handicapped children and youth. PMID- 4220653 TI - The National Defense Education Act and exceptional children. PMID- 4220655 TI - Shortcomings of grant applications to the handicapped children research program. PMID- 4220656 TI - CEC and legislation--now and in the future. PMID- 4220657 TI - Clearing house: a significant bill becomes law: the Community Mental Health Centers Act Amendments of 1965. PMID- 4220658 TI - "Teen Town"--exclusive community for exceptional children. PMID- 4220659 TI - [Epileptic manifestations with rare localization in muscles of abdominal pressure: pathogenetic considerations on a clinical case]. PMID- 4220660 TI - [Prevention of right cardiac overburdening in the mongoloid - electrocardiographic evaluations]. PMID- 4220661 TI - [Lysotyping with paper membranes (disks) impregnated with phages]. PMID- 4220662 TI - [On the 80th birthday of Professor Lorenz Bohler]. PMID- 4220663 TI - [Experiences with resection-angulation osteotomy by the Milch-Batchelor method in the treatment of bilateral coxarthrosis]. PMID- 4220665 TI - [Statistical contribution to dorsal displacement of vertebral bodies]. PMID- 4220664 TI - [Femoral head necrosis following steroid therapy]. PMID- 4220666 TI - [Data to the contraindication of laminectomy in patients with spinal deformities]. PMID- 4220667 TI - [On the progressive course of scoliosis associated with bone deformities]. PMID- 4220668 TI - [Vertebral meniscus of the synovial process]. PMID- 4220669 TI - [Paralysis of the brachial plexus as a rare late complication of fractures of the clavicle following fixation of the scapula]. PMID- 4220670 TI - [The tarsal sinus span]. PMID- 4220671 TI - [On the orthopedic symptomatology and treatment of the Ehlers-Danlos syndome. (Case report)]. PMID- 4220672 TI - [Contribution to the pathogenesis of Madelung's deformity, its transitional forms and conservative treatment]. PMID- 4220673 TI - [Contribution to the clinical picture of generalized interstitial calcinosis]. PMID- 4220674 TI - [Treatment of chronic osteomyelitis with antibacterial rinsing and drainage and continuous instillation]. PMID- 4220675 TI - [Contribution to the clinical picture of osteopsathyrosis (Lobstein)]. PMID- 4220676 TI - [Study on the conduction speed of the radial nerve]. PMID- 4220677 TI - [Concordant spondylolisthesis in a male-female pair of twins]. PMID- 4220678 TI - [Improved orthopedic care in tuberculous vertebral and joint diseases with supportive appliances from a new plastic material]. PMID- 4220679 TI - [On the consideration of the physiologic reflex mechanism of infants and young children in the treatment of scoliosis with corrective plaster beds]. PMID- 4220680 TI - [On an orthopedic appliance used in the treatment of pseudarthrosis of the leg]. PMID- 4220681 TI - [Improved stability in fixation of intratrochanteral osteotomy with the Bosworth plate]. PMID- 4220682 TI - [Contribution to the position of the foot in arthrodesis of the ankle joint]. PMID- 4220683 TI - [German Committee on Youth Dental Care]. PMID- 4220684 TI - [The modern child from the physician's viewpoint]. PMID- 4220685 TI - [A new Salmonella species: Salmonella zwickau 16:r(i): e,n, z15]. PMID- 4220686 TI - Aplastic anemia, histiocytosis and erythrodermia in immunologically deficient children. Probable human runt disease. PMID- 4220687 TI - Progestin-estrogen combinations in management of acne. PMID- 4220688 TI - Intensity of function of structures of the differentiated cell as a determinant of activity of its genetic apparatus. PMID- 4220689 TI - [Roentgenologic manifestations of parasitic diseases]. PMID- 4220690 TI - [How the expert can take into consideration the occupational factor in common law]. PMID- 4220692 TI - Studies on the cornea. IV. Some effects of ouabain on pinocytosis and stromal thickness in the rabbit cornea. PMID- 4220691 TI - [Inhibition of the active Na-K-transport and Na-K-activated membrane ATP-ase of erythrocyte stroma by ouabain]. PMID- 4220693 TI - Studies on the fibrinolysis in tumor bearing mice. IV. Mechanism of ascites retention with special reference to plasmin activity of tumor cell origin. PMID- 4220694 TI - [Experience in the virological detremination of Q fever in Kazkhstan]. PMID- 4220695 TI - Conference on criteria for, and evaluation of, orthopedic measures in the management of deformities of rheumatoid arthritis. PMID- 4220696 TI - [Natural history of interauricular communications]. PMID- 4220697 TI - Psychological aspects of physical disability. PMID- 4220698 TI - [Studies on the biosynthesis of testicular androgens]. PMID- 4220699 TI - [Magic remedy]. PMID- 4220700 TI - Disturbances of acid-base equilibrium resulting from salicylism in children. PMID- 4220702 TI - Interference and viral infection in a cell line derived from Burkitt's lymphoma. PMID- 4220701 TI - Summer in Siam. Report of a Smith Kline and French foreign fellowship to Thailand, June to September, 1964. PMID- 4220703 TI - Permeability of laparotomy sponges to cancer cells. PMID- 4220704 TI - Forty years of pediatrics. PMID- 4220705 TI - Marriage ... and medicine. PMID- 4220707 TI - Eye disorders in handicapped children. PMID- 4220706 TI - Life-threatening drug eruptions. PMID- 4220708 TI - Dr. Alvin E. Buckwold. An appreciation. PMID- 4220710 TI - [School dentist 1920-1964]. PMID- 4220709 TI - [Values of total fatty acid esters of the skin surface in adolescence--relation to acne]. PMID- 4220711 TI - Fibrosarcoma of the anterior abdominal wall. PMID- 4220712 TI - Parental age in Down's syndrome (mongolism). PMID- 4220714 TI - [Functional exploration of the ovary in women with discopathies of the degenerative type]. PMID- 4220713 TI - [A few chapters from the practice of an ophthalmological legal expert]. PMID- 4220715 TI - [Sensitization to chromium, cobalt and nickel compounds in patients with occupational eczema]. PMID- 4220716 TI - [Role of the vascularization around fractures and inside the bone marrow in restorative osteogenesis]. PMID- 4220717 TI - [Osteoplastic thrust or osteotomy of the pelvis?]. PMID- 4220719 TI - [Apropos of malignant bone reticuloses]. PMID- 4220720 TI - [Considerations on vetebral osteomyelitis (60 cases)]. PMID- 4220718 TI - [Prognosis of pelvic osteotomy in dislocations in older children and adults]. PMID- 4220721 TI - [Symposium on surgical sciatica of discal origin]. PMID- 4220722 TI - Effect of radiation on nuclear phosphorylation in human malignant tumours. PMID- 4220724 TI - [Cytogenic investigations in a case of Langdon-Down syndrome]. PMID- 4220723 TI - [On laparoscopic cholecysto-cholangiography]. PMID- 4220725 TI - Managing the disabled patient. PMID- 4220726 TI - Bacterial urease. A comparison of urease production with coagulase of Staphylococci and fibrinolysin of Pseudomonas aeruginosa. PMID- 4220727 TI - Incorporation of sulfate-35S, N-acetylglucosamine-1-14C, glucose-1-14C, and galactose-1-14C into calf and beef corneal glycosaminoglycans. PMID- 4220728 TI - Effects of 'pre-incubation' on the distribution of different enzymes in extracts of Escherichia coli. PMID- 4220729 TI - [Backaches and their differential diagnosis. I. Lumbar pain caused by organic factors]. PMID- 4220731 TI - Natural F-actin. I. Direct isolation of F-actin from myofibrils and its physico chemical properties. PMID- 4220730 TI - The participation of calcium, adenosine triphosphate and adenosine triphosphatase in the extrusion of the granule proteins from the polymorphonuclear leucocyte. PMID- 4220732 TI - Water extrusion in isolated subcellular fractions. IV. Simplified system to study the adenosine triphosphate-dependent reaction. PMID- 4220733 TI - The R-S ratio in lead V2 in the diagnosis of right ventricular hypertrophy. PMID- 4220734 TI - Plasma viscosity in mental deficiency and Down's syndrome. PMID- 4220735 TI - Serum seromucoid and acid mucopolysaccharide in malignant neoplastic diseases. PMID- 4220736 TI - [Subjective life experiences of handicapped children and adolescents]. PMID- 4220737 TI - [Notes on the epidemiology of leptospirosis]. PMID- 4220739 TI - [Transseptal catheterization and hemodynamics of mitral cardiopathies]. PMID- 4220738 TI - [Cellular metabolism and toxicity of ethyl alcohol]. PMID- 4220740 TI - [Natural peptides with antibiotic action]. PMID- 4220741 TI - [Occupational stigmata in brickmakers loading brick-coping in the brick kilns of Hodonin]. PMID- 4220742 TI - [Effects of the inhibition of hypophyseal activity with paroxypropione in acne vulgaris]. PMID- 4220744 TI - The real self. PMID- 4220743 TI - Pyloroplasty and vagotomy in treatment of duodenal ulcers--a preliminary report. PMID- 4220745 TI - Glomerulo-nephritis. PMID- 4220746 TI - Preparation for international travel. PMID- 4220747 TI - Let's sell Arkansas to our medical students and interns. PMID- 4220748 TI - Attitudes as determinants of behavior. PMID- 4220750 TI - Thyroid disease among children with Down's syndrome (mongolism). PMID- 4220749 TI - [Syndrome of congenital malformations of the abdominal wall muscles and of the renal tract in a newborn infant]. PMID- 4220751 TI - Whose chromosomes to count in mongolism? PMID- 4220753 TI - [Traumatology and malignant tumor with special reference to expert testimony]. PMID- 4220752 TI - [Hyposensitization trials]. PMID- 4220754 TI - [On the disease picture of protrusio acetabuli]. PMID- 4220755 TI - [Giant cell tumor of the bones in the region of the knee]. PMID- 4220756 TI - [Tibial head deformity, one of the causes for early arthrosis]. PMID- 4220757 TI - [Experimental studies on the traction function of the musculus tensor fasciae latae]. PMID- 4220758 TI - [Experimental studies on the origin of static scoliosis]. PMID- 4220759 TI - [Free bodies in the lateral meniscotibial joint]. PMID- 4220760 TI - [Scapula alata, caused by thoracic wall tumor]. PMID- 4220761 TI - [On the frequency of roentgenologically demonstrable structural irregularities of vertebral body caudal surfaces]. PMID- 4220763 TI - [Bone regeneration in fractures in patients with severe cranial injuries]. PMID- 4220762 TI - [Vertebral arch clefts in a human embryo of 14 mm vertex-to-breech length]. PMID- 4220764 TI - [Contribution to the early biochemical diagnosis of bone diseases]. PMID- 4220766 TI - [Closure rhythm and closure disorders of synchondrosis ischiopubica and their dependence on the pathology of the hip joint (contribution to the clinical aspects of the growing pelvis)]. PMID- 4220765 TI - [Contribution to dysplasia of the shoulder joint (with special reference to humerus varus)]. PMID- 4220767 TI - [Salter's pelvic osteotomy and varusizing derotation osteotomy of the proximal femoral end]. PMID- 4220768 TI - The dissimilation of glucose and gluconate by Acetobacter xylinum. 1. The origin and the fate of triose phosphate. PMID- 4220770 TI - Changing concepts in pedodontics. PMID- 4220769 TI - Mucopolysaccharides in kidneys of vertebrates of various classes. PMID- 4220771 TI - Training the child dental patient. PMID- 4220773 TI - Roentgenological manifestations of systematic diseases in children. PMID- 4220774 TI - The use of gold foil in dentistry for children. PMID- 4220772 TI - [Some histologic, physiologic and pharmacologic aspects of pulp treatment in pedodontics]. PMID- 4220775 TI - This is how to do it. PMID- 4220776 TI - Conservative dentistry gold in young permanent teeth. PMID- 4220777 TI - Idiopathic hypoventilation. PMID- 4220778 TI - The physician and postmyocardial infarction invalidism. PMID- 4220779 TI - Dentistry and the under fives. PMID- 4220780 TI - Premedicating pedodontic patients. PMID- 4220781 TI - [Attitude of the pediatrician toward the mongoloid infant]. PMID- 4220782 TI - Differentiation of leukocytic fibrinolytic enzymes from plasmin by the use of plasmatic proteolytic inhibitors. PMID- 4220783 TI - Some observations on the value of the electrocardiogram in patients with chronic cor pulmonale. PMID- 4220784 TI - Hematoma of the rectus abdominis muscle complicating anticoagulant therapy. PMID- 4220785 TI - [Pharyngeal tonsils and palatine tonsils in children with Down's syndrome]. PMID- 4220786 TI - [On the percentage of mucopolysaccharides, mucoproteins and nitrogen in the sputum under the influence of N-cyclohexyl-N-methyl-(2-amino-3,5-dibromo-benzyl-) ammonium chloride]. PMID- 4220787 TI - [On the nucleic acid content of the pathologically hypertrophied dog heart]. PMID- 4220789 TI - Interdisciplinary classification for the aged. PMID- 4220788 TI - [Autoradiographic and radiochemical investigation on the influence of whole body x-irradiation on the sulfomucopolysaccharide metabolism of the rat aorta]. PMID- 4220790 TI - Alterations in fibrinogen, plasminogen, and inhibitors of plasmin with the growth of V2 carcinoma in rabbits. PMID- 4220792 TI - [Aids in the daily life of the handicapped]. PMID- 4220791 TI - Fluorinated pyrimidines. XXVI. Mammalian thymidylate synthetase: its mechanism of action and inhibition by fluorinated nucleotides. PMID- 4220793 TI - Effects of heparin, plasmin, dextran, and low molecular dextran on bioelectrically induced thromboses. PMID- 4220794 TI - Removal of subarachnoid blood by the irrigation method. PMID- 4220795 TI - Collagen turnover and reorganization in secondary wounds. PMID- 4220797 TI - The noble gas ion laser as a light-knife. PMID- 4220796 TI - Liver dysfunction during protracted hepatic artery infusion of massive doses of fluorinated pyrimidine. PMID- 4220799 TI - A new phage type of Staphylococcus aureus associated with an outbreak of pemphigoid. PMID- 4220798 TI - [A histochemical contribution to the problem of oxyphilic granular cell carcinoma (malignant oncocytoma) in radium-treated "stages-tuberculosis" (scrophuloderma + lupus vulgaris)]. PMID- 4220800 TI - Intracutaneous injection of sebum and comedones. Histological observations. PMID- 4220801 TI - Fixed drug eruption (phenacetin). PMID- 4220802 TI - Down's syndrome and chronic myelogenous leukemia. PMID- 4220803 TI - Role of inorganic phosphate in stimulating the glucose utilization of human red blood cells. PMID- 4220804 TI - Two interconvertible forms of yeast phosphofructokinase with different sensitivity to endproduct inhibition. PMID- 4220805 TI - Erythema multiforme-like eruption due to sulfa. PMID- 4220806 TI - Speaking fundamental frequency (SFF) characteristics of mongoloid girls. PMID- 4220807 TI - [Evaluation of the relationship between meniscus lesions and working activities of day-laborers]. PMID- 4220808 TI - Studies on digitalis. XI. Effects of digitoxin on the development of cardiac hypertrophy in the rat subjected to aortic constriction. PMID- 4220809 TI - [Social reintegration of handicapped children]. PMID- 4220810 TI - The release of bound adenosine triphosphatase from isolated bacterial membranes and the properties of the solubilized enzyme. PMID- 4220812 TI - [Phytohemagglutinin and cell multiplication]. PMID- 4220811 TI - The metabolism of steroids by tissue from normal and neoplastic rat breast. PMID- 4220813 TI - [The evolution of essential polyglobulism. Importance of successive radiochromium and radio-iron tests]. PMID- 4220814 TI - [Myelin structures in spumous cells in Fabry's disease]. PMID- 4220815 TI - [2 cases of acute hemolytic anemia following intake of phenylsemicarbazide. Remarks on poikilocytosis and review of literature]. PMID- 4220817 TI - [Effects of transfusions of serum during Willebrand's disease]. PMID- 4220816 TI - [Study of a case of megaloblastic anemia in a child with abnormal excretion of orotic acid]. PMID- 4220818 TI - [Prolonged spontaneous remission of chronic lymphoid leukemia]. PMID- 4220819 TI - [Chromosomal anomalies and disappearance of the substance H in a patient of the O group suffering from myeloblastic leukosis]. PMID- 4220821 TI - [Aplasia of the bone marrow due to dinitrophenol with complete remission followed by an acute leukosis]. PMID- 4220820 TI - [Myeloma, hyperlipemia and xanthomatosis]. PMID- 4220822 TI - [Counting of crythrocytes, leukocytes and blood platelets with an electronic particle counter]. PMID- 4220823 TI - [Myeloid splenomegaly and anal tumor with myeloblasts]. PMID- 4220824 TI - [Neutrophil granulocytic reaction and a malignant pleural tumor]. PMID- 4220825 TI - ["In vitro" test of blood platelet spread]. PMID- 4220826 TI - [3 cases of dysglobulinemia]. PMID- 4220827 TI - Frog gastric mucosal ATPase. PMID- 4220829 TI - Urinary excretion of testosterone in idiopathic hirsuitism. PMID- 4220828 TI - Acid mucopolysaccharides in rat skin. An electrophoretic study of dermal and subcutaneous tissue. PMID- 4220830 TI - [Sputum mucopolysaccharides]. PMID- 4220831 TI - Interrelationship of human plasma kallikrein and plasmin in inflammation. PMID- 4220832 TI - Effect of hydrocortisone on UDPG-dehydrogenase. PMID- 4220833 TI - [Effects of x-irradiation and various substances on the nature of erythrocyte permeability]. PMID- 4220835 TI - Kinetics of (Na+ + K+)-stimulated ATPase of rabbit kidney microsomes. PMID- 4220834 TI - [Use of alphamucase in surgery]. PMID- 4220836 TI - Structure and properties of the acetone adducts of 1-n-propyl nicotinamide iodide. PMID- 4220837 TI - Titration of mitochondrial adenosinetriphosphatase with desaspidin. PMID- 4220838 TI - Mercury Resistance of Staphylococcus aureus. PMID- 4220839 TI - Education for the exceptional child. PMID- 4220840 TI - Skin problems in the school-age child. PMID- 4220841 TI - [The ultrastructure and swelling process of collagen]. PMID- 4220842 TI - [Autoradiographic investigations on the control of S-35-sulfate incorporation into fibroblasts in tissue culture]. PMID- 4220843 TI - Studies on the isolation and composition of interstitial fluid in swine dentine. PMID- 4220844 TI - [Menopause and metabolic disorders]. PMID- 4220845 TI - A study of rose bengal and sulfhydryl reagents on stromal fragments of rabbit and human erythrocytes. PMID- 4220846 TI - [Outpatient treatment of intestinal diseases with Mexaform S]. PMID- 4220847 TI - Valedictory address. PMID- 4220848 TI - Haemorrhagic fever in children in Penang. PMID- 4220849 TI - Types of C. diphtheriae in Kuala Lumpur. PMID- 4220850 TI - Leucocyte alkaline phosphatase, leucocyte count and haemoglobin level in malayan new-borns and young infants. PMID- 4220851 TI - Steady state analysis of BSP distribution between liver and plasma following single injection in intact dogs. PMID- 4220852 TI - The prepuerin test in pregnancy: report of a trial. PMID- 4220853 TI - Evaluation of intra uterine contraceptive devices. PMID- 4220854 TI - Surgical induction of labour in modern obstetrics. PMID- 4220855 TI - Seminal stains--identification and grouping. PMID- 4220856 TI - A note of caution on the use of crystalline bovine albumin as a reference standard in the estimation of serum proteins. PMID- 4220857 TI - The importance of ante-natal ABO-Rh-antibody determination. PMID- 4220858 TI - Patella cubiti. PMID- 4220859 TI - Granulomatous peritonitis due to Ascaris eggs. PMID- 4220860 TI - Maduromycosis of the forearm in a Bajau native of Sabah. PMID- 4220861 TI - Chromoblastomycosis of the arm in a Chinese in Sabah. PMID- 4220862 TI - A brief review of the diabetes mellitus, heart disease and blood pressure studies. PMID- 4220863 TI - Vitamin C deficiency and connective tissue. 3. Determinations of hexosamine, uronic acid, hydroxyproline and uptake of radiosulfate (35S) in granulation tissue. PMID- 4220864 TI - The natural history of ventricular septal defects in infancy. PMID- 4220865 TI - The natural history of pulmonary valvular stenosis. Serial cardiac catheterizations in 21 children. PMID- 4220866 TI - Annulo-aortic ectasia with cystic medial necrosis. Diagnosis and surgical treatment. PMID- 4220868 TI - [Results of lysotyping of 2233 staphylococcus aureus strains]. PMID- 4220867 TI - Association of pulmonary valvular stenosis and muscular ventricular septal defect. Report of a case in a patient aged 75 years. PMID- 4220869 TI - Phosphofructokinase activity of blood cells in leukemia. PMID- 4220870 TI - [The effect of agar poly-anions and heparin on cytopathic manifestations of various arboviruses]. PMID- 4220871 TI - [Vitamin B-1 and pantothenic acid as growth factors for Shigella flexneri]. PMID- 4220872 TI - [Identification of various systematic mycoses by means of agar precipitation]. PMID- 4220873 TI - [Surface distribution of dermatophytes in a natural site]. PMID- 4220874 TI - [An epidemic of tularemia in the North Bohemian region in 1961-1962]. PMID- 4220875 TI - [Dynamics of antibodies against tularemia following immunization with a live tularemia vaccine]. PMID- 4220876 TI - [An attempt to use the immunofluorescence method in the diagnosis of enteropathogenic E. coli]. PMID- 4220877 TI - [Isolation of Emmonsia crescens Emmons et Jellison 1960 in the territory of Czechoslovakia]. PMID- 4220878 TI - [Elimination of cattle brucellosis in Czechoslovakia]. PMID- 4220879 TI - [Classification and characteristics of penicillin derivatives]. PMID- 4220880 TI - [Contents of the fibrinolysis activator in the myometrium of the non-pregnant uterus and in labor]. PMID- 4220881 TI - Federal employment of the mentally and emotionally restored. PMID- 4220882 TI - [Fluocinolone and iodochlorhydroxyquin in allergic dermatosis. Topical use]. PMID- 4220883 TI - [Lumbago in balneotherapy]. PMID- 4220884 TI - [Plasmin and kinin forming system in the skeletal muscle and the serum under application of the tourniquet]. PMID- 4220885 TI - Farmer's lung, a new industrial disease. PMID- 4220886 TI - Industrial problems relating to the stratum corneum. PMID- 4220888 TI - Alkaptonuria, ochronosis, and low-back pain. A case report. PMID- 4220887 TI - The action of thiol inhibitors on the interaction of F-actin and heavy meromyosin. PMID- 4220889 TI - [Electrocardiogram and serum enzyme activity following experimental traumatic heart injuries in relation to the pathologic-anatomic findings]. PMID- 4220891 TI - [Isolated tibial and fibular fractures]. PMID- 4220890 TI - [Remote results of the treatment of tibial head fractures]. PMID- 4220892 TI - [Bilateral spontaneous cleft in the os naviculare carpi]. PMID- 4220893 TI - [Conservative therapy in closed injuries of the extensor tendon in the distal phalanges of the fingers]. PMID- 4220894 TI - [A new type of plaster of paris cast in the treatment of femoral fractures in severe combined injuries]. PMID- 4220895 TI - The pathology of laser irradiation of the skin and body wall of the mouse. PMID- 4220896 TI - Effects of denervation on normal and dystrophic muscle: DNA and nucleotide enzymes. PMID- 4220897 TI - Effect of right ventricular hypertrophy on infundibular pressure gradients in dogs. PMID- 4220899 TI - [Sympathetic system and visual system]. PMID- 4220898 TI - Activation of thrombolysis by streptokinase in the cat. PMID- 4220900 TI - [Cryosurgery]. PMID- 4220901 TI - [Senile macular degeneration. Treatment with heparin and its derivatives]. PMID- 4220902 TI - [Dermatitis caused by plastic putty]. PMID- 4220904 TI - [Convulsions caused by dentition]. PMID- 4220905 TI - Care of staff's back. PMID- 4220903 TI - The localization of adenosine triphosphatases in morphologically characterized subcellular fractions of guinea-pig brain. AB - 1. The distribution of adenosine triphosphatase was studied in morphologically characterized subcellular fractions of guinea-pig brain. The conditions of homogenization were selected so as to favour the survival of nerve endings as organized structures. 2. A fraction consisting mainly of the external membranes of nerve endings was rich in a ouabain-sensitive Na(+)-K(+)-stimulated adenosine triphosphatase which closely resembled that present in the classical microsomal fraction studied by other workers, but which showed a higher specific activity. 3. A dinitrophenol-stimulated adenosine triphosphatase was located in the nerve ending mitochondria. 4. The synaptic-vesicle fraction contained a small amount of adenosine triphosphatase that differed in its response to several ions and other compounds from the membrane, myelin and mitochondrial fractions, indicating freedom from contamination by these elements. PMID- 4220906 TI - [Statistical study of the activity of the surgical units of the Army Medical Corps during the Algerian Insurrectional War (1954-1962)]. PMID- 4220907 TI - [Cardiologic exploration in a military hospital environment. Technic of non surgical investigations. Results]. PMID- 4220908 TI - [Reduction of the time of unavailability during sport training under the action of an oral anti-inflammatory]. PMID- 4220909 TI - [A world center of pathological anatomy: "The Armed Forces Institute of Pathology" of Washington (United States)]. PMID- 4220910 TI - [The chronology of the preparation for firing a rocket bearing an experimental animal]. PMID- 4220911 TI - Neuromuscular transmission in vivo and the actions of decamethonium: a micro electrode study. PMID- 4220912 TI - Constituents of a microsomal fraction from the mammalian brain: their solubilization, especially by detergents. PMID- 4220913 TI - Determination of oxo steroids as coloured salts of their Girard derivatives. PMID- 4220914 TI - Staphylococcus bacteriophage patterns. PMID- 4220915 TI - [Psychic blindness in tunnel vision?]. PMID- 4220916 TI - Methods of detecting cancer antigens and antitumor antibody. PMID- 4220917 TI - Use of antimetabolites in the study of normal and abnormal cell structure and function. PMID- 4220918 TI - Antibodies against the various types of skeletal muscle fibres. PMID- 4220919 TI - [Extensive ulcerative caseous pulmonary tuberculosis and infra-radiologic silicosis. Medico-legal discussion]. PMID- 4220920 TI - Intractable cardiac failure. PMID- 4220921 TI - Quantitative study of sensitive and lysogenic bacteria surviving infection of a Staphylococcus by a temperate bacteriophage. PMID- 4220922 TI - Corneal dystrophies associated with abnormalities of mucopolysaccharide metabolism. PMID- 4220924 TI - [Onychomycoses caused by Scopulariopsis brevicaulis]. PMID- 4220925 TI - Study of the provision of dental care for handicapped children. PMID- 4220923 TI - Oxidative phosphorylation. Biochemical effects and properties of trialkyltins. PMID- 4220926 TI - The effects of dental treatment on behavior of handicapped patients. PMID- 4220927 TI - Ethnocentrism and attitudes toward the physically disabled. PMID- 4220928 TI - Human position sense and sense of effort. PMID- 4220929 TI - [Dermatologic problems in industry and their prevention]. PMID- 4220930 TI - [On the role of yeasts in the etiology of Danbolt-Closs acrodermatitis enteropathica]. PMID- 4220931 TI - [Acne vulgaris and liver preparations. A contribution to the etiology of acne vulgaris]. PMID- 4220932 TI - Inhibition of citrate metabolism by sodium fluoroacetate in the perfused rat heart and the effect on phosphofructokinase activity and glucose utilization. PMID- 4220933 TI - Vectorial aspects of adenosine-triphosphatase activity in erythrocyte membranes. PMID- 4220936 TI - [Determination of dehydroepiandrosterone and androsterone sulfate in the blood]. PMID- 4220934 TI - Structural and enzymic aspects of the hydrolysis of adenosine triphosphate by membranes of kidney cortex and erythrocytes. PMID- 4220935 TI - Studies in immunochemistry. 23. Some observations on the heterogeneity of preparations of human blood-group-specific substances. PMID- 4220937 TI - Cytochemical evaluation of metabolic inhibitors in cell culture. PMID- 4220938 TI - ATP level and cleavage of sea urchin eggs Strongylocentrotus drobachiensis (O. F. Muller). PMID- 4220939 TI - Rate determining step of the coupled reaction system composed of H-meromyosin adenosinetriphosphatase and creatine kinase. PMID- 4220940 TI - [On the problem of "contractility" of lens proteins]. PMID- 4220941 TI - [Correlations between the sodium of the arterial walls, arterial lesions and arterial pressure in hypertensive rabbits]. PMID- 4220942 TI - [An anatomical wall chart from the 18th century]. PMID- 4220943 TI - [Wilhelm von Lack's "Art of the bladder stone" and several other prescriptions for urinary diseases by unknown authors of the middle ages]. PMID- 4220944 TI - [France's efforts to obtain better hospitals]. PMID- 4220945 TI - [The verdict of the "untreatable disease" in ancient Egyptian medicine]. PMID- 4220946 TI - The introduction and use of eastern drugs in the early middle ages. PMID- 4220947 TI - [Haller's book reviews]. PMID- 4220948 TI - [The oldest miners' and casualty hospital in Germany]. PMID- 4220949 TI - [Volume measurement of normal and pathological hearts]. PMID- 4220950 TI - [Rupture of the heart after infarction. (Current therapeutic perspects)]. PMID- 4220951 TI - Regulation of glucose uptake by muscle. 7. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, on the concentrations of hexose phosphates, nucleotides and inorganic phosphate in perfused rat heart. PMID- 4220953 TI - Scadan lotion--a new preparation in the treatment of seborrhea. PMID- 4220954 TI - Fibrinolytic activity of blood in rheumatic fever. PMID- 4220952 TI - Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles. PMID- 4220956 TI - Chronic disease and employability: the physician's role. PMID- 4220955 TI - Alcoholism in industry. PMID- 4220958 TI - Occupational medicine--the modern view. PMID- 4220957 TI - Epidemiologic data on diseases of female workers in Yugoslavia. PMID- 4220959 TI - Careers. PMID- 4220960 TI - The pre-steady state of the myosin-adenosine triphosphate system. I. Initial rapid liberation of inorganic phosphate. PMID- 4220961 TI - The pre-steady state of the myosin-adenosine triphosphate system. II. Initial rapid absorption and liberation of hydrogen ion followed by a stopped-flow method. PMID- 4220962 TI - The pre-steady state of the myosin-adenosine triphosphate system. 3. Properties of the intermediate. PMID- 4220963 TI - ATP-induced contraction of sarcomeres. PMID- 4220964 TI - Effect of thermal treatment on the calcium sensitivity of myosin B at low ionic strength. PMID- 4220965 TI - Acute liver injury in ducklings as a result of aflatoxin poisoning. PMID- 4220966 TI - Vitamin C deficiency and connective tissue. II. Determinations of hexosamine, uronic acid and hydroxyproline in guinea pig carcasses. PMID- 4220967 TI - [Thrombolytic medication in ophthalmology. II]. PMID- 4220969 TI - [General anesthesia for children]. PMID- 4220970 TI - [Backache from the psychosomatic viewpoint]. PMID- 4220968 TI - The isolation and properties of epithelial-cell "ghosts" from rat small intestine. AB - 1. The preparation of gram quantities of isolated epithelial-cell ;ghosts' from mucosal scrapings of rat small intestine is described. The method involves dispersing the tissue by gentle homogenization in 6% dextran in Krebs-Ringer phosphate, pH7.4, followed by filtration through nylon cloth and sedimentation by low-speed centrifuging. 2. The isolated epithelial-cell ;ghosts' contained all of the DNA, but only 52% of the protein and 53-57% of the RNA of the original homogenate. They contained most of the activity of the following enzymes found in the homogenate: aminopeptidase (71%); alkaline beta-glycerophosphatase (82%); invertase (92%); adenosine triphosphatase (93-116%); acid beta-glycerophosphatase (83%); nonspecific esterase (76%); succinate dehydrogenase (96%). Only small proportions of the total lactate-dehydrogenase (10%) and phosphoglucose-isomerase (2%) activities found in the homogenate were recovered in the isolated cell ;ghosts'. 3. The epithelial-cell ;ghost' preparation did not respire unless cofactors and substrates were added, and did not consume glucose or produce lactic acid from glucose. 4. The effect of varying the composition of the homogenization medium was studied. Concentrations of dextran (mol.wt. 15x10(4)) from 1 to 12%, solutions of dextrans (all at 6%) with mol.wt. varying between 3.6x10(4) and 2x10(6), and a solution of 8% polyethylene glycol (mol.wt. 4000) served equally well for the production of epithelial-cell ;ghosts'. Two of these solutions, however, 12% dextran (mol.wt.15x10(4)) and 6% dextran (mol.wt. 2x10(6)), were too viscous to allow the complete sedimentation of the cell ;ghosts' at low relative centrifugal forces. Omission of either Krebs-Ringer phosphate or dextran from the medium resulted in almost complete cell breakage during the homogenization. 5. The isolated cell ;ghosts' were used as a starting material for subcellular fractionation of rat intestinal mucosa by differential centrifugation. The distributions of protein and succinate-dehydrogenase activity among the fractions were compared with corresponding values in fractions isolated by differential centrifugation of mucosa homogenized in 0.3m-sucrose-5mm-EDTA, pH7.4. The method in which cell ;ghosts' were used as starting material gave a better separation and cleaner fractions than the method in which untreated mucosal scrapings were used. PMID- 4220971 TI - [Contribution to the knowledge of desmoid tumors of the abdominal wall in infancy]. PMID- 4220972 TI - Today's dentistry for today's children. PMID- 4220973 TI - Incidence of dental anomalies encountered in pedodontics. PMID- 4220974 TI - [The concept of "helplessness in the sense of paragraph 558 of the Reich Insurance Regulations" in jurisprudence]. PMID- 4220975 TI - [Fractures of amputation stumps and amputated limbs]. PMID- 4220977 TI - [Relief suture in tendon surgery]. PMID- 4220976 TI - [Changes of iron metabolism following bundle nailing]. PMID- 4220978 TI - [A contribution to primary care of the burned hand]. PMID- 4220979 TI - [Parietal fibroplastic endocarditis and generalized endangiitis following chronic suppuration]. PMID- 4220980 TI - [Spontaneous rupture of the normal spleen]. PMID- 4220981 TI - [Essential decisive exacerbation of a bone sarcoma caused by accidental fracture and following medullary nailing]. PMID- 4220982 TI - [Macromolecular orientation of mucopolysaccharides in human cementum]. PMID- 4220983 TI - [Histochemical detection of mucopolysaccharides in human cementum]. PMID- 4220984 TI - Observations on the inhibition of preparations of porcine plasmin by serum and by urinary trypsin inhibitor (mingin). PMID- 4220985 TI - [Hemocytochemical findings in chronic occupational sulfopathy]. PMID- 4220986 TI - [Studies on collagen fibers. V. On changes due to aging in connective tissue. (Comparative chemical and morphological studies]. PMID- 4220987 TI - Idiopathic prepuberal hypertrophy of the male breast. Histochemical evaluation and relation to gynecomastia and other disorders of the breast. PMID- 4220988 TI - Effects of freezing on the stability of staphylococcal phages. PMID- 4220989 TI - [Lesion of the dental organ under the medico-legal profile]. PMID- 4220990 TI - [Social security of self-employed workers. Medico-legal aspects]. PMID- 4220991 TI - A study of uterine actn. PMID- 4220992 TI - Intestinal transport of glucose in the silkworm, Bombyx mori L. PMID- 4220994 TI - Studies in human malignant tissue. I. Protein synthesis in malignant & normal cervix uteri. PMID- 4220993 TI - Effects of metals & reducing agents on the incorporation of amino acids into lens RNA & protein. PMID- 4220995 TI - Lysophosphatidyl ethanolamine of certain species of mycobacteria. PMID- 4220996 TI - Carbohydrate metabolism in experimental tuberculosis: hepatic enzymes related to glycogen metabolism & synthesis of glycogen from labelled glucose. PMID- 4220997 TI - Pigments of unclassified mycobacteria. I. Nature of pigments in a scotochromogenic strain (P-15) of mycobacteria. PMID- 4220998 TI - Chromatography of plant lytic enzymes on carboxymethyl cellulose. PMID- 4220999 TI - Some observations on the properdin system. VI. Preparation and properties of buffalo serum properdin. PMID- 4221000 TI - N and C-terminal amino acids of collagen and its examination for the blocking of terminal amino groups by hexoses. PMID- 4221001 TI - Aconitate isomerase in sugar cane. PMID- 4221002 TI - Protein bound hexosamine and hexoses in blood of normal adults and children, and pulmonary tuberculosis patients. PMID- 4221003 TI - Occurrence of acid-soluble and acid-insoluble polyphosphates in rabbit liver. PMID- 4221004 TI - Action of tetanus toxin on brain and liver mitochondria of resistant and susceptible animals. PMID- 4221005 TI - Metabolic activity of starch granules from the tapioca plant. II. Functional activity of starch granules from tuber. PMID- 4221006 TI - Microbiological transformations of terpenes. V. Origin of 2-nonene, 2,3 dicarboxylic acid anhydride in the fermentation of terpenoid hydrocarbons by Aspergillus niger. PMID- 4221007 TI - Effect of some chemical modifications on the biological activity of catalase. PMID- 4221008 TI - Effect of protein depletion on ribonucleic acid metabolism in rat liver. PMID- 4221009 TI - Role of vitamin A in sulphate metabolism. I. Studies on sulphate incorporation into mucopolysaccharides in vitamin A deficient rats. PMID- 4221010 TI - Effect of insulin on the resynthesis of glycogen in cerebral cortical slices. PMID- 4221011 TI - Vitamin B12 & 14C incorporation into cell proteins of Escherichia coli 113-3. I. Incorporation studies with resting cells. PMID- 4221012 TI - Spontaneous rupture of the rectus abdominis muscle. PMID- 4221013 TI - Fractionation of mycoplasma cells for enzyme localization. PMID- 4221014 TI - [On occupational disability in regard to compensation insurance for the laborer according to the law of 2-23-1957 for the legal rearrangement of compensation insurance for the laborer]. PMID- 4221015 TI - [Causes of disability of the urban population of the city of Frunze. (Preliminary report)]. PMID- 4221016 TI - [Khaiat Shagibekovna Enikeeva. (On her 60th birthday)]. PMID- 4221017 TI - [Spondylogenic pelvipathy]. PMID- 4221018 TI - Respiratory control by an adenosine triphosphatase involved in active transport in brain cortex. PMID- 4221020 TI - Identification of active phosphoprotein in a cation-activated adenosine triphosphatase. PMID- 4221019 TI - The regulation of kidney respiration by sodium and potassium ions. PMID- 4221021 TI - Urocanic acid in keratinizing tissue. PMID- 4221022 TI - Characteristics of the ATP-ase activity of isolated neurons of rabbit. PMID- 4221023 TI - [Acariasis from grain, from the occupational angle]. PMID- 4221024 TI - [Physicians in ordinary of several Salzburg archbishops in the late middle ages]. PMID- 4221025 TI - [Hematoma of the musculus rectus abdominis simulating torsion of an ovarian cyst]. PMID- 4221026 TI - A rapid pH-stat assay for phosphofructokinase and the forward reaction of phosphoglucose isomerase. PMID- 4221027 TI - Adenosine triphosphatase activity in the rod outer segments of the pig retina. PMID- 4221028 TI - Enzymatic sulfation of steroids by bovine tissues. PMID- 4221029 TI - Catalysis in reactions of 1-benzyl-1,4-dihydronicotinamide. PMID- 4221030 TI - Purification, crystallization and properties of activated sheep heart phosphofructokinase. PMID- 4221031 TI - Highly specific sodium-potassium-activated adenosine triphosphatase from various tissues of rabbit. PMID- 4221032 TI - Some acyl phosphate-like properties of P32-labeled sodium-potassium-activated adenosine triphosphatase. PMID- 4221033 TI - Taming the monster in the chair. PMID- 4221034 TI - The localization of myofibrillar ATPase activity in the flight muscles of the blowfly, Calliphora erythrocephala. AB - The distribution of ATPase activity in the asynchronous flight muscles of Calliphora erythrocephala (Diptera) was studied at a fine structural level, using preparations of teased fibers, both unfixed and after brief fixation in hydroxyadipaldehyde, incubated in a medium for the histochemical demonstration of myosin or actomyosin ATPase. In relaxed fibrils, activity was found confined to the A bands and was absent from the H zones as well as from the Z and I band regions. At high magnification, deposits of final product, lead phosphate, appeared primarily related to the thick filaments, or to short lateral extensions from them. Evidence was gathered which indicated that this enzyme activity was that of a triphosphatase which did not act on dinucleoside or non-nucleoside substrates. PMID- 4221035 TI - The effect of UV-radiation on HeLa cells infected with adenovirus. PMID- 4221036 TI - Sodium, potassium-requiring adenosinetriphosphatase activity. II. Mechanism of inhibition by sulphydryl reagents. PMID- 4221037 TI - Familiarity, dogmatism, and reported student attitudes toward the disabled. PMID- 4221038 TI - [Studies on the phenology of seborrhoeic dermatoses and psoriasis in the province of Lublin]. PMID- 4221040 TI - On the presence of mucopolysaccharide material in the labyrinthine epithelium of chick embryo in the first moments of morphogenesis. PMID- 4221039 TI - [Results of dopan therapy of lymphogranulomatosis based on the data of the Khirgizin Scientific Research Institute of Oncology and Radiology]. PMID- 4221041 TI - [Treatment of gastroduodenal ulcer with Condrovister]. PMID- 4221042 TI - [Epicardiac activation in right intra-ventricular conduction disorders in man]. PMID- 4221043 TI - Steroid metabolism in the syndrome of testicular feminization. PMID- 4221044 TI - Feminizing adrenal tumor in a six-year-old boy. PMID- 4221045 TI - Southeast Asian Haemaphysalis ticks (Ixodoidea, Ixodidae). H. bandicota sp. n. from bandicoot rats in Taiwan, Thailand, and Burma. PMID- 4221046 TI - [Central disk hernias and neurologic signs]. PMID- 4221047 TI - The effects of fibrinolysin upon tendon healing in the dog. PMID- 4221048 TI - [Evaluation of work incapacity in amputations and possibilities of influencing it in a positive fashion]. PMID- 4221049 TI - Clinical studies on the cardiac performance by means of transseptal left heart catheterization. II. Left ventricular function in high output heart diseases, especially in hyperthyroidism. PMID- 4221050 TI - Nucleic acid metabolism in experimentally hypertrophied myocardium. PMID- 4221051 TI - The effect of oral potassium chloride on the normal and abnormal electrocardiogram; studies on the ventricular gradient II. PMID- 4221052 TI - [Problems of regional medicine in Uzbekistan]. PMID- 4221053 TI - Blood pressure elevation and renal pathology in rats fed simulated Japanese diets. PMID- 4221054 TI - Vitamin B6 depletion in man: urinary excretion of quinolinic acid and niacin metabolites. PMID- 4221055 TI - [Legislation on occupational diseases in agriculture and their compensation]. PMID- 4221056 TI - [Lipids of the erythrocyte membrane in Huntington's disease]. PMID- 4221057 TI - [Heart size in the obese. Heart size and its relationship to body height, weight and mass in obese and proportionally developed boys]. PMID- 4221058 TI - [Several electrocardiographic changes in the reversible insufficiency of the right heart]. PMID- 4221059 TI - The enzymatic degradation of heparin and heparitin sulfate. I. The fractionation of a crude heparinase from flavobacteria. PMID- 4221060 TI - Characterization of the molecular region containing the active sites of myosin. PMID- 4221061 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. V. Properties of coupling factor 4. PMID- 4221062 TI - Formation of a reactive myosin-phosphate complex as a key reaction in muscle contraction. PMID- 4221064 TI - [Contribution to the vascular supply of the os naviculare of the hand]. PMID- 4221065 TI - [Results of suture of peripheral nerve of upper extremities]. PMID- 4221063 TI - [Variations in the development of the bony skeleton and its significance in accident surgery]. PMID- 4221066 TI - [Studies on the behavior of serum alkaline phosphatase during healing of fractures]. PMID- 4221067 TI - [On the crush syndrome of the kidneys and its treatment]. PMID- 4221068 TI - [Self-observation in 2 stage splenic rupture. Deduction for an expert opinion]. PMID- 4221069 TI - The pattern of innervation of the extrinsic ocular muscles and the intra-orbital ganglia of the albino mouse. PMID- 4221070 TI - [Dermatitis seborrheica]. PMID- 4221072 TI - Anxiety--reappraisal of a concept. PMID- 4221071 TI - Carbon monoxide poisoning. PMID- 4221073 TI - Breech presentation in the primigravida. PMID- 4221074 TI - Diagnosis of Cushing's syndrome. PMID- 4221075 TI - Electrocardiogram of the month. PMID- 4221076 TI - Available services in nutrition and dietetics. PMID- 4221078 TI - Early atherosclerosis in the pig: a histological and histochemical study. PMID- 4221077 TI - [On the influence of shock and hyperlipidemia on lipid content, lipid synthesis and mucopolysaccharide synthesis in the blood vessel wall]. PMID- 4221079 TI - Multiple repeat caesarean section. PMID- 4221081 TI - Clinical pathologic conference. PMID- 4221080 TI - [On the enzymatic regulation of glucuronide synthesis in the liver of newborn rats]. PMID- 4221082 TI - [Statistics of the consultation service on occupational dermatoses in the Clinique Dermatologique de Lyon in 1963]. PMID- 4221084 TI - [Physical handicaps incompatible with the driver's license and industrial medicine]. PMID- 4221083 TI - [Cutaneous accidents caused by thioformol polymers]. PMID- 4221085 TI - [The main problems of the organization for the control of occupational dermatoses]. PMID- 4221087 TI - [Determination of allergens in occupational dermatoses using local galvanic skin reactions]. PMID- 4221086 TI - [On the problem of cement dermatoses]. PMID- 4221088 TI - [On the significance of epicutaneous colophony tests]. PMID- 4221089 TI - [Covert and manifest sensitization caused by phenothiazine derivatives (propaphenine and prothazine) in the nursing personnel of 2 psychiatric hospitals]. PMID- 4221090 TI - [Job-related skin diseases in the drug industry]. PMID- 4221092 TI - [Studies on skin resistance to chemicals used to decrease the electrostatic charging of textiles]. PMID- 4221091 TI - [Skin damage in the manufacture of synthetic fiber materials from cellulose]. PMID- 4221093 TI - [On rare occupational dermatoses in farm and slaughterhouse workers]. PMID- 4221094 TI - [Causes of occupational dermatoses in the preparation and processing of dyes and lacquers]. PMID- 4221095 TI - [Results in the elimination of sensitizing materials from industrial products in the DDR]. PMID- 4221096 TI - [On the etiology and pathogenesis of Wegener's syndrome]. PMID- 4221098 TI - [Various operative technics observed and practiced in the pedodontic clinic of the Arrian Hospital with Dr. Matilda Thunin]. PMID- 4221100 TI - Fibrinolysin (human) in large therapeutic doses; its effect on hemostasis in wound-healing in dogs. PMID- 4221101 TI - Back pain: the problems of diagnosis. PMID- 4221102 TI - [Investigations on mucopolysaccharides in blood serum of some collagenoses]. PMID- 4221103 TI - Human dermal fibroblasts in monolayer tissue culture. Effect of ascorbic acid analogues. PMID- 4221104 TI - Factors influencing the utilization of ketone bodies by mouse adipose tissue. AB - Factors influencing the utilization of ketone bodies by mouse adipose tissue in vitro were studied. Epididymal fat pads can oxidize DL-Beta-hydroxybutyrate-3 (14)C and acetoacetate-3-(14)C to (14)CO(2) as well as convert these compounds to fatty acid-(14)C. An increased output of (14)CO(2) from Beta-hydroxybutyrate-3 (14)C was noted in response to glucose plus insulin, succinate, oxaloacetate, L asparate, and L-malate. Fatty acid synthesis from Beta-hydroxybutyrate was enhanced by glucose plus insulin, L-aspartate, L-malate, oxaloacetate, and citrate. Nicotinamide stimulated the oxidation of Beta-hydroxybutyrate but not of acetoacetate to CO(2), and did not affect fatty acid synthesis from either ketone body. Nicotinamide increased NAD(+) and NADP(+) levels in epididymal fat pads without affecting the concentration of NADH and NADPH. "Superlipogenesis" caused by fasting the mice for 48 hr and re-feeding them for 24 hr sharply enhanced CO(2) output and lipogenesis from Beta-hydroxybutyrate. The activities of glucose 6-phosphate dehydrogenase, 6-phosphogluconic dehydrogenase, NADP-malic dehydrogenase, and citrate cleavage enzyme from mouse adipose tissue were increased during "superlipogenesis." Free fatty acid release by epididymal fat pads in vitro was slightly increased by Beta-hydroxybutyrate. The relationship of ketone body metabolism and lipogenesis in adipose tissue is discussed. PMID- 4221105 TI - A comparative study of the influence of chlorpromazine and imipramine on mitochondrial activity. DNP- and Mg2+-activated ATPase, succinate dehydrogenase and aspartate transaminase. PMID- 4221106 TI - [Omphalocele and gastroschisis]. PMID- 4221107 TI - [The teaching of odontology as a university function]. PMID- 4221108 TI - [Investigation of a malaria outbreak in an area in the consolidation phase]. PMID- 4221109 TI - [Community nutrition problems in Chile]. PMID- 4221110 TI - [Study of the health status of the municipality of Funza, Colombia]. PMID- 4221112 TI - [Spindle potentials induced by stimulation of fusimotor fibers in the cat]. PMID- 4221111 TI - [Technical assistance of the Pan American Health Organization in the field of water supply]. PMID- 4221113 TI - The possibility of predicting the response of patients with early breast cancer to subsequent endocrine ablation. PMID- 4221114 TI - Effect of fluoropyrimidines on delayed cutaneous hypersensitivity. PMID- 4221115 TI - The spine as an indicator. PMID- 4221116 TI - [The biosynthesis of androgens in normal and Stein-Leventhal ovaries from dehydroepiandrosterone-4-C-14]. PMID- 4221117 TI - [Methylation of nicotinamide in schizophrenics--in vitro experiments (preliminary note)]. PMID- 4221118 TI - [Lumbar pain as a result of muscle fatigue in welders due to constrained positions during work at shipyards]. PMID- 4221119 TI - Interrelation between human chorionic gonadotrophin inhibitory activity in plasma and urine and the rate of urinary gonadotrophin excretion. PMID- 4221120 TI - Formation in vitro of dehydroepiandrosterone conjugates in blood. PMID- 4221121 TI - The phosvitin kinase enzyme of cerebral microsomes. PMID- 4221122 TI - Sodium-potassium activated ATPase from spinal cord of normal and injured rats. PMID- 4221124 TI - [Contribution to the evaluation of occupational skin diseases]. PMID- 4221123 TI - Inhibition of the sodium-ion-stimulated adenosine triphosphatase after treatment of isolated guinea pig cerebral cortex with ouabain and other agents. PMID- 4221125 TI - [Research concerning the relations between the fermentative properties and pathogenicity of staphylococci]. PMID- 4221126 TI - Monoamine oxidase activity of blood platelets and their ability to store 5 hydroxytryptamine in some mental deficiencies. PMID- 4221127 TI - [Production of lung and liver tumors in mice with N,N'-dinitrosopiperazine]. PMID- 4221128 TI - [Transplantation and chemotherapy of foreign body tumors in rats]. PMID- 4221129 TI - [On the morphology of tumors of the nasal cavity in the rat]. PMID- 4221130 TI - Chromosomes in two cases with acute childhood leukemia. PMID- 4221132 TI - [Effect of a carcinogenic methylnitrosourea doses on the embryonic development of the rat]. PMID- 4221131 TI - [Carcinogenic effect of azoethane and azoxyethane on rats]. PMID- 4221133 TI - [Significance of fatty granular cells in the sputum for the diagnosis of lung cancer]. PMID- 4221134 TI - [Experiments on carcinogenesis in vitro. Analysis of chromosomes and cytophotometric measurements of the DNA-content]. PMID- 4221135 TI - [Cytophotometric measurements of the DNA content on human and animal experiments with bronchial epithelial metaplasias]. PMID- 4221136 TI - [RNA content and volume of nucleoli in the rat liver during experimental carcinogenesis with diethylnitrosamine]. PMID- 4221137 TI - [On the problem of the effectiveness of d-glyceraldehyde]. PMID- 4221138 TI - [On occupational dermatoses in laborers in the Zwickau coal mines (with statistical interpretation on 4 pits during the past 5 years]. PMID- 4221140 TI - Sugar consumption in vitro of the muscle tissue of diabetic patients. PMID- 4221139 TI - [Current occupational dermatoses in agricultural districts]. PMID- 4221141 TI - [Sulfacetamide B 6: new treatment of the seborrheic dermatoses]. PMID- 4221142 TI - [Changes in plasmatic fibrinolytic activity in patients with cardiovascular diseases]. PMID- 4221143 TI - Congenital aplasia of the myocardium of the right ventricle (Uhl's anomaly). PMID- 4221144 TI - Clinical application of antidepressant agents in disabled and rehabilitation patients. PMID- 4221145 TI - Fibrinolytic activity in thrombosed veins. PMID- 4221146 TI - Inhibition of the biosynthesis of sulphurated mucopolysaccharides in metaphyseal cartilage of newborn pigs. PMID- 4221147 TI - [Critical remarks on the problem of the enzymatic treatment of wounds with special reference to burns]. PMID- 4221148 TI - Recombination in bacteriophage T4: a mechanism. AB - Genetic recombination between rIl mutants of T4 bacteriophage grown in Escherichia coli can occur under conditions where DNA synthesis is strongly inhibited by 5-fluorodeoxyuridine. The small amount of DNA synthesized under these conditions cannot account for the observed frequency of recombinants. The major mechanism of recombination in this system is a process of breakage and rejoining. PMID- 4221150 TI - [On the clinical diagnosis of nail trichophytosis]. PMID- 4221149 TI - Influence of thiol-inhibiting substances on the effects of ethyl methane sulphonate (EMS) on chromosomes. PMID- 4221151 TI - [The eponychium as portal of entrance for fungal infections of the nail]. PMID- 4221152 TI - [Nail fungus types in the area of Plovdiv, Bulgaria]. PMID- 4221153 TI - [Findings in intermittent griseofulvin treatment of nail mycoses]. PMID- 4221154 TI - [Views on the significance of occupational dermatitis]. PMID- 4221155 TI - [Allergological problems in occupational eczema]. PMID- 4221156 TI - [Occupational eczema in seborrheic subjects]. PMID- 4221157 TI - [Alkali compatibility of seborrheic skin areas]. PMID- 4221159 TI - [On various occupational dermatoses caused by air-borne allergens]. PMID- 4221158 TI - [Lipid-water emulsion system and skin types]. PMID- 4221160 TI - [Why is common acne generally localized in the face, breast, back and upper 3d of the arms? (Attempt toward clarification on the basis of a case of generalized occurring common acne)]. PMID- 4221161 TI - Histochemical study on localization of adenosine triphosphatase and 5 nucleotidase in the olfactory bulb of the rat. PMID- 4221163 TI - Oral lesions of erythema multiforme. Histologic and histochemical observations. PMID- 4221162 TI - [Histochemical studies of rat skin after continuous application of oligo-N-methyl morpholiniumpropylene oxide]. PMID- 4221164 TI - Demodex folliculorum and rosacea. A clinical and histological study. PMID- 4221165 TI - An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement. PMID- 4221166 TI - [A new criteria for diagnosis of enlargement of the right ventricle]. PMID- 4221167 TI - [Left ventricular hypertrophy. Its electrocardiographic diagnosis]. PMID- 4221168 TI - [Investigations of toxoplasmosis]. PMID- 4221169 TI - [The use of an antigen of the Patoc strain of Leptospira biflexa in field investigations of leptospirosis]. PMID- 4221170 TI - [Status of rabies on the northern border of Mexico]. PMID- 4221171 TI - [Coordinated program of communicable disease control in Honduras]. PMID- 4221172 TI - [Need for integration of the health services and social welfare]. PMID- 4221173 TI - [Perinatal care in the state of Guanabara, Brazil]. PMID- 4221175 TI - [The rubber dam for children]. PMID- 4221174 TI - [Ecology of childhood]. PMID- 4221176 TI - [Recent true femoral neck fractures]. PMID- 4221177 TI - Anomalous origin of the left coronary artery from the pulmonary artery. PMID- 4221178 TI - Congenital aortic stenosis due to failure of histogenesis of the aortic valve (myxoid dysplasia). PMID- 4221179 TI - Syndrome of incomplete regional achondroplasia (ilium and ribs) with abdominal muscle dysplasia. PMID- 4221180 TI - [Outbreak of equine encephalomyelitis in the Republic of Panama]. PMID- 4221181 TI - [Experimental stenosis of the thoracic aorta in rats. (A model of cardiac defect and hypertrophy)]. PMID- 4221182 TI - The aromatization of 10-methyl and 10-hydroxymethyl steroids by human placental microsomes. PMID- 4221183 TI - Comparative anticoagulant effects of coumadin, heparin, and fibrinolysin on direct-current thrombosis of rat mesoappendix vessels. PMID- 4221184 TI - The frequency of aganglionosis associated with imperforate anus. PMID- 4221185 TI - [Enzyme histochemical studies on regeneration of the aorta in animal experiments]. PMID- 4221187 TI - [Love, intelligence and will]. PMID- 4221186 TI - Dermatoglyphics in translocation Down's syndrome. PMID- 4221188 TI - Control of the carriage of epidemic phage type staphylococci and recurrent sepsis by biological means. PMID- 4221189 TI - Studies of male survivors of myocardial infarction. VI. The electrocardiogram. AB - Electrocardiograms of 101 men who survived myocardial infarction for at least three months and were free of hypertension, heart failure and other significant disease were analyzed. Within the range of 30 to 70 years, age had no apparent influence on the ECG. Six ECGs were borderline, 79 were abnormal and 16 had returned to normal. Of those with the pattern of infarction, 56 were transmural and 22 nontransmural. For all cases, posterior involvement was somewhat more common than anterior (46 to 32), but it was less common in non-transmural infarction. Ventricular premature beats, always unifocal and few in number, were the only abnormality in rhythm. Atrial fibrillation was conspicuously absent. There were four instances of complete left bundle-branch block. No evidence of left ventricular hypertrophy was seen. The clinical significance of these observations is briefly discussed. PMID- 4221190 TI - The concept of susceptibility to hearing loss. PMID- 4221191 TI - Medical aspects of invalidity retirement programs in Europe. II. PMID- 4221192 TI - Compensation for injuries while commuting to and from work. PMID- 4221193 TI - Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 3. Formation of deciduomata. PMID- 4221194 TI - Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. 4. Regression of deciduomata. PMID- 4221195 TI - The acid mucopolysaccharides. These essential components of living tissue exhibit demonstrable alterations of diagnostic assistance in certain diseases. PMID- 4221196 TI - [Biomechanical role of the bone-muscle composite beams]. PMID- 4221197 TI - [On the primary and secondary treatment of closed leg fractures]. PMID- 4221198 TI - [Harrington's operation in the surgical treatment of scoliosis]. PMID- 4221199 TI - [A certain "benign tumor" of the head of the fibula]. PMID- 4221200 TI - Chromosomal aberrations in acute leukemia. PMID- 4221202 TI - Mechanism of formation of bovine plasminogen activator from human plasmin. PMID- 4221201 TI - Comparative biochemistry of keratosulfates. PMID- 4221203 TI - Adenosine triphosphatase activity of yeast hexokinase and its relation to the mechanism of the hexokinase reaction. PMID- 4221204 TI - Studies on the secretion and interconversion of the androgens. II. Methods for estimation of rates of secretion and of metabolism from specific activities of urinary metabolites. PMID- 4221205 TI - Studies on the secretion and interconversion of the androgens. 3. Results obtained after the injection of several radioactive C-19 steroids, singly or as mixtures. PMID- 4221206 TI - Plasma testosterone and estrogen levels, urine testosterone excretion, and sebum production in males with acne vulgaris. PMID- 4221207 TI - Physically crippled, but emotionally secure. PMID- 4221208 TI - [The nail and Candida albicans]. PMID- 4221209 TI - Re-employment or retirement. Background and definitive statement of the problem of disability. PMID- 4221210 TI - Scleredema. PMID- 4221211 TI - Oral enzyme therapy in treatment of acne: a preliminary report. PMID- 4221212 TI - Lysis of arterial clots. Using fibrinolysin in an isolation perfusion system. PMID- 4221213 TI - [Transverse palmar fold and dermatoglyphs]. PMID- 4221214 TI - The cardiac pathology of chronic exogenous obesity. PMID- 4221215 TI - Prolonged bed rest in the treatment of the dilated heart. PMID- 4221216 TI - The identification of successful teachers of mentally or physically handicapped children. PMID- 4221217 TI - Changes in heart muscle and liver proteins in experimental myocardial infarction. PMID- 4221218 TI - Effect of irradiation on vascular permeability and on blood mucopolysaccharide and serotonin levels. PMID- 4221219 TI - [The lysosomes in phagocytic cells]. PMID- 4221220 TI - [Viruses and human leukemia]. PMID- 4221221 TI - [ Chromosome analysis of a clonal development in a case of myeloid leykemia]. PMID- 4221222 TI - [Action of adenosine-5-monophosphoric acid and inosine on experimental porphyria induced in rats by griseofulvin]. PMID- 4221223 TI - [Leukocytes and fibrinolysis]. PMID- 4221224 TI - [The disk-sphere transformation of human erythrocyte stroma: 2 new phenomena]. PMID- 4221225 TI - [Thalassemia in the Indians of French Guiana]. PMID- 4221226 TI - [A new antigen of the ABO system: A1(80)]. PMID- 4221227 TI - [Development and prognosis of idiopathic pancytopenia. Study of 116 cases]. PMID- 4221228 TI - [Microtubules and fibrils in spread-out platelets]. PMID- 4221230 TI - [On causes of blindness in children]. PMID- 4221229 TI - [The problem of the lysosomes]. PMID- 4221231 TI - [On the use of infrared absorption spectroscopy for the identification of lipoids on the skin surface]. PMID- 4221232 TI - [Histologic studies on tar-induced skin diseases with special reference to verruca picea]. PMID- 4221233 TI - Benzene and dioxane electric moments of N-alkyl-substituted nicotinamides from measurements in mixed benzene--dioxane solutions. PMID- 4221235 TI - [Aid to aged and disabled persons]. PMID- 4221234 TI - [Centro-medullary nailing of the tibia in the treatment of recent diaphysial leg fractures in adults]. PMID- 4221236 TI - Thyroid function in mongoloid children. Thyroxine-binding capacity. PMID- 4221237 TI - Management of femoral artery obstruction. Complications of femoral venipuncture. PMID- 4221238 TI - [Results of a 4-year serial test on apprentices of the hairdresser profession]. PMID- 4221239 TI - [Etiopathogenetic role of brown coal (lignite)]. PMID- 4221240 TI - The management of tube pedicles. PMID- 4221241 TI - [Occupational contact eczema caused by vitamin K]. PMID- 4221242 TI - The effects of temperature on the isolated muscle spindle. PMID- 4221243 TI - Motor fibres innervating extrafusal and intrafusal muscle fibres in the cat. PMID- 4221244 TI - A bath that folds--from Sweden. To facilitate bathing of very ill or disabled patients. PMID- 4221245 TI - In right good company. PMID- 4221246 TI - Nutritional status of people in isolated areas of Puerto Rico. Survey of Barrio Mavilla, Vega Alta, Puerto Rico. PMID- 4221247 TI - [Comparative actions of testosterone, dehydroepiandrosterone (DHA) and dehydroepiandrosterone on the hypophysial gonadotropic function of the prepuberal female rat]. PMID- 4221248 TI - Regulatory mechanisms in carbohydrate metabolism. VII. Hexokinase and phosphofructokinase. PMID- 4221249 TI - Regulatory mechanisms in carbohydrate metabolism. 8. The regulatory function of phosphate in glycolysis. PMID- 4221250 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. VI. Studies on the mechanism of cold inactivation of mitochondrial adenosine triphosphatase. PMID- 4221251 TI - Dio-9, an inhibitor of coupled electron transport and phosphorylation in chloroplasts. PMID- 4221252 TI - [Action of a diminution of spindle activity on reflex hyperventilation during passive mobilization in dogs]. PMID- 4221253 TI - [Differential effect of stimulations of the caudate nucleus and frontal cortex on the dynamic sensitivity of primary spindle endings in the cat]. PMID- 4221254 TI - Pediatric conditions related to diseases and functions of the placenta. PMID- 4221255 TI - Birth trends in Nebraska. PMID- 4221257 TI - The acute abdomen complicating pregnancy. PMID- 4221256 TI - Neurologic manifestations of dysbarism (decompression sickness). PMID- 4221258 TI - Etiology of carcinoma: genetic determinism. PMID- 4221259 TI - XII. The disabled patient at home. PMID- 4221261 TI - Reflex discharges in phrenic and abdominal muscle nerves to vagal afferent nerve stimulation. PMID- 4221260 TI - Subcutaneous rupture of the rectus abdominus muscle with incarcerated hernia and bowel obstruction. PMID- 4221262 TI - Low backache. PMID- 4221263 TI - [The process of restoration after irradiation observed at the organism, tissue and cell levels]. PMID- 4221264 TI - [Kinetic aspects of the restoration of irradiated cells]. PMID- 4221265 TI - [Considerations on the association of chemotherapy and radiotherapy]. PMID- 4221266 TI - [Radiocancerogenesis and the problem of restoration]. PMID- 4221267 TI - [The regeneration processes after irradiation and their relation to the problem of radiolesions]. PMID- 4221268 TI - [Recent research on total-body irradiation and bone marrow transplantation in humans]. PMID- 4221269 TI - [Depression and restoration of the regenerative capacity of the peripheral nerve after x-ray application]. PMID- 4221270 TI - [Discussion on the genetic control of the sensitivity of microorganisms to the lethal action of radiations]. PMID- 4221271 TI - [Regeneration of the nerve centers and meninges]. PMID- 4221272 TI - [Radio-sensitizing agents and methods of increasing radiosensitivity]. PMID- 4221273 TI - [Endometriosis of an abdominal scar caused by a fistula of the uterus and abdominal wall]. PMID- 4221274 TI - [Cytological and biochemical studies of the middle ear secretion during otitis media chronica adheasiva]. PMID- 4221275 TI - [Gas gangrene of the abdominal wall]. PMID- 4221276 TI - [Conditions of the cardiovascular system under the condition of moderate mountain climate in Shusha spa]. PMID- 4221277 TI - Differentiation of the skeletal muscle in the chicken. 8. ATPase activity during development. PMID- 4221278 TI - Platelet agglutination and deagglutination with a sulfhydryl inhibitor, methyl mercuric nitrate: relationships to platelet ATPase. PMID- 4221279 TI - Nuclear lobe count and incidence of drumsticks in Indian children with Down's syndrome. PMID- 4221280 TI - [The adaptation of society to the handicapped]. PMID- 4221281 TI - [Effect of dehydroepiandrosterone and atromid on the serum uric acid level]. PMID- 4221282 TI - Testicular feminization. PMID- 4221283 TI - Familial male hermaphroditism with delayed and partial masculinization. PMID- 4221284 TI - [Ocular complications caused by synthetic antimalarials]. PMID- 4221285 TI - [Some practical remarks apropos of intraocular foreign bodies]. PMID- 4221286 TI - [The vascular tonogram]. PMID- 4221287 TI - [Comments on the surgery of pterygium]. PMID- 4221288 TI - [Trial of a new technic for extraction of the cataractous crystalline lens]. PMID- 4221289 TI - [Glaucoma]. PMID- 4221290 TI - [Mechanical model of the de-efferent neuromuscular spindle: primary and secondary endings]. PMID- 4221291 TI - Mongolism in newborn infants. An examination of the criteria for recognition and some speculations on the pathogenic activity of the chromosomal abnormality. PMID- 4221292 TI - An autopsy case of Sezary's reticulosis. PMID- 4221293 TI - Studies on acid mucopolysaccharides of pig gastric mucin. I. PMID- 4221294 TI - [On hypertrophy of the ventricles in chronic chagas' heart disease]. PMID- 4221295 TI - [Treatment of acne in male patients with anovulatory compounds]. PMID- 4221296 TI - [Technic of preparation of an afferent I fiber and an afferent II fiber innervating the same neuromuscular spindle, in the cat]. PMID- 4221297 TI - Biochemical differentiation of trisomic Down's syndrome (mongolism) from that due to translocation. PMID- 4221298 TI - [Chemical aspects of folic acid deficiency]. PMID- 4221299 TI - [The hematologic nocuity of lead. Findings in 40 patients hospitalized for occupational saturnism]. PMID- 4221300 TI - [Glutathione synthesis during congenital hemolytic anemia with reduced glutathione deficiency. Congenital erythrocytic glutathione-synthetase deficiency?]. PMID- 4221301 TI - [Blood serum levels of methionine and vitamin B12 during Biermer's anemia. Comparison with levels in normal controls]. PMID- 4221302 TI - ["Essential" dysglobulinemia in aged subjects]. PMID- 4221303 TI - [Viewpoints on the dynamics of the cell surface]. PMID- 4221304 TI - [A case of acquired hemolytic anemia, with leukopenia and thrombopenia, in pregnancy]. PMID- 4221306 TI - [Results of 2 years' treatment of perinatal hemolytic disease. Results and current problems]. PMID- 4221305 TI - [Histological lesions of the bone marrow during the initial period of acute leukemia in adults. Study by marrow biopsy]. PMID- 4221308 TI - [Study of primary hemostasis in rats after total irradiation]. PMID- 4221307 TI - [Myeloma, hyperlipidemia and xanthomatosis. II. Complementary research on the association between paraprotein and fast lipoproteins]. PMID- 4221309 TI - [Myeloma, hyperlipidemia and xanthomatosis. 3. A syndrome due to the presence of an anti-beta-lipoprotein autoantibody]. PMID- 4221310 TI - The orthopedic aspects of low back pain. PMID- 4221311 TI - [Institutional structure of the water supply agencies]. PMID- 4221313 TI - [The problem of induced abortion in Chile]. PMID- 4221312 TI - [Geographical distribution of iodine deficiency in Latin America]. PMID- 4221314 TI - [Infantile diarrhea and malnutrition]. PMID- 4221315 TI - Occupational dermatitis. PMID- 4221317 TI - Handicapped children. The problem and a plan for their rehabilitation. PMID- 4221316 TI - Diagnosis of industrial dermatitis. PMID- 4221318 TI - Current occupational health in Latin America. PMID- 4221319 TI - Compensation for injuries in fighting. PMID- 4221320 TI - Remediation of learning disabilities in a public school system. PMID- 4221321 TI - Body image of crippled children as seen in draw-a-person test behavior. PMID- 4221322 TI - Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. I. Framework: oestrous cycle and pseudopregnancy. PMID- 4221323 TI - Studies on the mechanism of nidation. XVII. Histochemical analysis of decidualization in the rat. II. Induction. PMID- 4221324 TI - Acute anemia and abdominal tumor due to hemorrhage in rectus abdominis sheath following anticoagulant therapy. PMID- 4221325 TI - Chromosome studies on a radiographer and her family. Report of one case of leukemia and two cases of Down's syndrome. PMID- 4221326 TI - A simple test for inactivation of an enzyme during assay. PMID- 4221327 TI - [The different means of compensation for bodily injury]. PMID- 4221328 TI - [Practical advice]. PMID- 4221329 TI - Effect of the antimetabolite, 6-aminonicotinamide, on sound-induced seizures in mice. PMID- 4221330 TI - [Effect of fibrinolysin on the pulmonary and bronchial vascular tonus]. PMID- 4221331 TI - [Effect of local anesthetics on the adenosinetriphosphatase activity of the brain]. PMID- 4221332 TI - Vocational rehabilitation service in a general hospital. PMID- 4221333 TI - The effect of nucleic acid antagonists on cell division and oral organelle development in Tetrahymena pyriformis. PMID- 4221334 TI - [Contribution to the physiopathogenesis of obesity. I. Dehydroepiandrosterone]. PMID- 4221335 TI - [Research on muscular contraction in backache and sciatica patients]. PMID- 4221336 TI - [Pelentan eczema]. PMID- 4221337 TI - [Problems concerning neglected traumatic hip dislocations]. PMID- 4221338 TI - [Possibilities of primary and secondary soft tissue repair of the upper extremity]. PMID- 4221339 TI - [Subtotal vertebra resection on the cervical spine]. PMID- 4221340 TI - [Total fusion of the atlas and epistropheus]. PMID- 4221341 TI - [Studies on twins concerning the hereditary determination of the closure of the vertebral arch in the lumbosacral region]. PMID- 4221342 TI - [Nonspecific spondylitis following nucleography and disk operations]. PMID- 4221343 TI - [Contribution to the Klippel-Trenaunay syndrome]. PMID- 4221344 TI - [On the open reduction of congenital hip dislocation]. PMID- 4221345 TI - [Functional treatment with the old dislocation bandage]. PMID- 4221346 TI - [On the treatment of progressive muscular dystrophy with glucose insulin infusions]. PMID- 4221347 TI - [Resection of the knee joint]. PMID- 4221348 TI - [New surgical method in ruptured cruciate ligaments]. PMID- 4221349 TI - [Experimental studies on the effectiveness of organ extracts on cartilage tissue]. PMID- 4221350 TI - [Changes on the homolateral knee joint in coxitis of children]. PMID- 4221351 TI - [So-called infantile scoliosis from a new viewpoint]. PMID- 4221352 TI - [Preliminary report on operations in chronically recurrent lumbago]. PMID- 4221353 TI - [A pair of new surgical elevators]. PMID- 4221354 TI - Beryllium disease. Report of the section of nature and prevalence committee on occupational diseases of the chest--American College of Chest Physicians. PMID- 4221355 TI - Demonstration of 3-beta-hydroxysteroid dehydrogenase in the testis of Tilapia mossambica (Cichlidae, Teleostei). PMID- 4221356 TI - Intramuscular pressure changes during contraction in relation to muscle spindles. PMID- 4221357 TI - Effects of heparin, plasmin, dextran and low-molecular-weight dextran on electrically induced thromboses. PMID- 4221358 TI - [Man and his environment. Biomedical knowledge and social action]. PMID- 4221359 TI - [Technical discussion: ways to improve vital and health statistics. Final report]. PMID- 4221360 TI - [Some principles of epidemiology]. PMID- 4221361 TI - [Immunity of the population of La Guajira, Colombia, in April 1963, to Venezuelan encephalitis virus]. PMID- 4221362 TI - [Iodochloroxyquinoleine in the treatment of infantile diarrheas]. PMID- 4221363 TI - The challenge of research in oral pediatrics. PMID- 4221364 TI - [Ungual mycosis]. PMID- 4221365 TI - [Clinical, social and insurance evaluation of professional deafness due to noise]. PMID- 4221366 TI - [The principal problems encountered by the expert]. PMID- 4221367 TI - The effect of oligomycin on the respiration of tissue slices. PMID- 4221369 TI - The role of CA2+ in the adenosine triphosphatase activity of myofibrils. PMID- 4221368 TI - The effect of long-chain fatty acids on orthophosphate-adenosine 5'-triphosphate exchange activity associated with oxidative phosphorylation. PMID- 4221370 TI - [Experiences with the fluorescence antibody method in the diagnosis of human herpetic keratoconjunctivitis]. PMID- 4221371 TI - [Utilization of autoradiography in the analysis of the antigen-antibody precipitation systems]. PMID- 4221372 TI - [Viruses in enlarged tonsils and adenoid vegetations]. PMID- 4221373 TI - [Contribution to the problem of animal reservoirs of trichophytosis and evaluation of their significance for man]. PMID- 4221374 TI - [Occupational illness with Q fever in the district of Jihlava]. PMID- 4221375 TI - [Classification and characteristics of tetracycline antibiotics]. PMID- 4221376 TI - [New modification of Gassner's culture medium]. PMID- 4221377 TI - [Mental plug for the bacteriological test tube as the carrier of the smear tampon]. PMID- 4221378 TI - [Apropos of 170 cases of peritoneoscopy performed during the course of hepatic cirrhosis]. PMID- 4221379 TI - A method for the demonstration of sulphated mucopolysaccharides in tissue sections. PMID- 4221380 TI - Cutaneous focal mucinosis. A clinicopathological and histochemical study. PMID- 4221381 TI - Scleromyxedema. A variant of Lichen myxedematosus. PMID- 4221382 TI - Tetracycline sun sensitivity. PMID- 4221383 TI - Oral tetracycline treatment on bacterial flora in acne vulgaris. PMID- 4221384 TI - The child, the parent and the dentist. PMID- 4221386 TI - How many disabled? PMID- 4221385 TI - The uses and limitations of hypnosis in children's dentistry. PMID- 4221387 TI - [Adrenal cortex hormones and biosynthesis of acid mucopolysaccharides. UDP glucose: NAD oxidoreductase activity in subcutaneous granuloma and in the liver of rats adrenalectomized and treated with cortisol and deoxycorticosterone (DOC)]. PMID- 4221388 TI - Activity patterns of purified ATPase from Arachis hypogaea. PMID- 4221389 TI - Legal implications of the battered child syndrome. PMID- 4221390 TI - Wilful abuse of children. PMID- 4221392 TI - "Nonparticipation" and the Sherman Act. PMID- 4221391 TI - Response of malignancy to phenylalanine restriction. A preliminary report on a new concept of managing malignant disease. PMID- 4221393 TI - "The role of Blue Shield in the medicare program". PMID- 4221394 TI - [Comparative study of the effects of various drugs (curariform, ATPase inhibitors, antiserotonin) on muscle contraction and clot retraction]. PMID- 4221395 TI - A rapid method for the assay of small quantities of sulfomucopolysaccharides. PMID- 4221396 TI - [Transformation, in vitro, of dehydroepiandrosterone by the spermatozoids of Scyliorhinus canicula L]. PMID- 4221397 TI - The variation of adenosine triphosphate and adenosine triphosphatase in Tribolium confusum, Duval at the different stages of its life cycle. PMID- 4221399 TI - An address given at the dedication of the Davis Woolf Goldstein Library. PMID- 4221398 TI - [On the binding of calcium ions to the Na+-K+-stimulated adenosine triphosphatase system of the brain]. PMID- 4221400 TI - Olfactory groove meningioma: herniation following spinal anesthesia. PMID- 4221401 TI - Disaccharide intolerance. PMID- 4221402 TI - Leukoplakia of the vulva. PMID- 4221403 TI - The humoral regulation of erythropoiesis. PMID- 4221404 TI - Typhoid fever. PMID- 4221405 TI - The role of lysosomes in hypersensitivity reactions: tissue damage by polymorphonuclear neutrophil lysosomes. PMID- 4221406 TI - Targets of population in Singapore. PMID- 4221407 TI - Immunization in virus disease. PMID- 4221408 TI - Factors affecting prognosis of choriocarcioma. PMID- 4221409 TI - A plea against abdominal hysterotomy in the treatment of hydatidiform mole. PMID- 4221410 TI - Behaviour therapy. PMID- 4221411 TI - A malaria parasite, plasmodium (Vinckeia) booliati sp.nov., from a Malayan giant flying squirrel. PMID- 4221412 TI - Pudendal block anaesthesia. A new technique in regional anaesthesia with special reference to forceps delivery. PMID- 4221413 TI - Aflatoxins in unrefined groundnut oil. PMID- 4221414 TI - The oxygen consumption of Plasmodium berghei in the presence of normal rat serum, immune rat serum and chloroquine sulfate. PMID- 4221416 TI - Studies on the cytology and histology of helminths. PMID- 4221415 TI - Systematic and distributional studies of helminths of Malayan mammals. PMID- 4221417 TI - The lymphatic system of a species of amphistome. PMID- 4221419 TI - The life-history of Echinostoma ilocanum. PMID- 4221418 TI - Morphological, histological and cytological studies on the nervous system of Ceylonocotyle sp. (Paramphistomata). PMID- 4221420 TI - The life cycle of two brachylaimid flukes in Malaysia. PMID- 4221421 TI - Multiple infections of larval trematodes in one snail. PMID- 4221422 TI - Fascioliasis in cattle near Kuala Lumpur. PMID- 4221423 TI - A single abnormal proglottid Taenia saginata. PMID- 4221424 TI - The size of microfilariae in relation to the storage time of unfixed and fixed thick blood films. PMID- 4221425 TI - Intraocular parasitism. PMID- 4221426 TI - Correlation of habitat to rodent susceptibility with Angiostrongylus cantonensis (Nematoda: Metastrongylidae). PMID- 4221427 TI - Studies on Hepatojarakus malayae Yeh, 1955 (Trichostrongylidae: Nematoda). PMID- 4221428 TI - Observations on the presence of immunity in rats to Angiostrongylus cantonensis (Chen). PMID- 4221429 TI - The American cockroach, Periplanta americana, as an intermediate host of the pentastomid, Raillietiella hemidactyli. PMID- 4221430 TI - Laboratory observations on the comparative feeding preferences by Aedes schuellaris malayensis from Kuantan and Singapore. PMID- 4221431 TI - Anopheles maculatus, a new vector of Wuchereria bancrofti in Malaysia (Pulau Aur) and a potential vector on mainland Malaya. PMID- 4221432 TI - Anopheles philippinensis, a new host record of Coelomomyces sp. in Perlis. PMID- 4221433 TI - Anopheles balabacensis balabacensis identified as a vector of monkey malaria in malaya. PMID- 4221434 TI - A tracheal mite from Valanga nigricornis Burm. (Orthoptera: Acrididae). PMID- 4221436 TI - Laboratory diagnosis of trachoma. PMID- 4221435 TI - The unusual life-history of Vatacarus ipoides Southcott (Acarina, Trombiculidae). PMID- 4221437 TI - Rapid typing of dengue viruses by the microprecipitin agar gel diffusion technique. PMID- 4221438 TI - Laboratory diagnosis of haemorrhagic fever. PMID- 4221439 TI - Mycotic Keratitis. PMID- 4221440 TI - Coagulation of Malays and caucasians: a comparative study of two groups of young soldiers. PMID- 4221441 TI - Freeze-dried smallpox vaccine; report of a trial in Kuala Lumpur. PMID- 4221442 TI - ["Banal" lumbalgia due to transverse apophysis]. PMID- 4221443 TI - A familial minute isochromosome. PMID- 4221445 TI - [Theoretical principles of "family psychotherapy" of children with developmental defects]. PMID- 4221446 TI - [Heat exchange in aerospace physiology]. PMID- 4221444 TI - Autoimmunity and chromosomal aberrations. PMID- 4221447 TI - [Protection of the aviator against environments with elevated temperatures]. PMID- 4221448 TI - [Nutritional problems raised by glucoregulation in aviation]. PMID- 4221449 TI - [Hypoglycemia and discomfort in aviators]. PMID- 4221450 TI - [Some electrocardiographic anomalies and aptitude for employment of navigation personnel]. PMID- 4221451 TI - [Statistical data concerning gastroduodenal ulcers in members of of the navigation staff of the air force]. PMID- 4221452 TI - [Duration of disability in a selected group of diseases in a collective of persons receiving disability compensation who died in Brno 1957-1960]. PMID- 4221453 TI - [The Polygone School, "Section of the motor-handicapped". Its place in the education of young-motor-handicapped individuals]. PMID- 4221454 TI - [Health education of the families of the handicapped]. PMID- 4221455 TI - [On an objective method for the study of the phenomenon of muscular defense]. PMID- 4221456 TI - [Dehydroepiandrosterone deficiency --a new syndrome?]. PMID- 4221458 TI - Rhabdomyosarcoma. PMID- 4221459 TI - Tuberculosis: is it compensable or not? PMID- 4221457 TI - The bacteriology of tropical pyomyositis in Uganda. PMID- 4221460 TI - [Acute hemorrhagic pancreatitis complicated by a voluminous, subsequently suppurative, hematoma of the abdominal wall]. PMID- 4221461 TI - More help in the home for the handicapped. PMID- 4221462 TI - [Effectiveness of combined spa-climatic therapy of patients with rheumatic heart diseases during different seasons in southern Crimea]. PMID- 4221463 TI - The relaxing incision in the anterior rectus sheath in the operative treatment of inguinal hernia. PMID- 4221464 TI - [Experimental chronic pulmonary hypertension in animals after recurrent microembolism of the lungs and their reaction on the heart and arteries]. PMID- 4221466 TI - [Prophylaxis of dranculosis by destruction of the "Cyclops" by means of a synthetic organic derivative, zinc dimethyldithiocarbamate or Zirame]. PMID- 4221465 TI - [A fabulous and enigmatic parasite: "The extraordinary worm" of John Paisley (1734) or "Nettorhynque" of Henri Ducrotay de Blainville (1824)]. PMID- 4221467 TI - [The sulfatides. (Structure--biosynthesis--metabolism)]. PMID- 4221468 TI - [Enzymatic and immunochemical isolation and characterization of some enzymes of the swine pancreas]. PMID- 4221469 TI - The sulfated mucopolysaccharides from human umbilical cord. PMID- 4221470 TI - The genetic mucopolysaccharidoses. PMID- 4221471 TI - [Puberty and mongolism (auxologic study of 10 cases)]. PMID- 4221472 TI - [Cooperation in affairs of the handicapped]. PMID- 4221473 TI - [Environmental problems of the handicapped in the foreground]. PMID- 4221474 TI - [A rare form of a so-called cloacal deformity with missing abdominal wall closure and double umbilical cord]. PMID- 4221475 TI - [Fibrinolysis in the eye. 3. Distribution of tissue activator and antiplasmin]. PMID- 4221476 TI - [Inhibitory effect of sodium chondroitin sulfate upon epithelial keratitis induced by naphazoline]. PMID- 4221477 TI - [Reparation for work accidents of agricultural operators]. PMID- 4221478 TI - A state department-university approach in providing internship experiences for prospective leadership personnel in special education. PMID- 4221479 TI - Psychological needs and preferences for teaching exceptional children. PMID- 4221480 TI - Effectiveness of an academically oriented teaching program with crippled children. PMID- 4221481 TI - The origin of spontaneous contractions and changes in neuromuscular transmission in barium-treated muscle. PMID- 4221483 TI - [Handicapped families in a welfare state]. PMID- 4221482 TI - [Rehabilitation work]. PMID- 4221484 TI - [Mycological study of 85 cases of onychopathy]. PMID- 4221485 TI - [Differentiation of the skeletal muscle in the white rat. II. Glycides]. PMID- 4221486 TI - Experimental collagen-like disease induced by repeated injections of papain, with evidence of autoimmune antibodies. PMID- 4221487 TI - [Proprioceptive innervation in otorhinolaryngology]. PMID- 4221489 TI - Exchange of cerebrospinal fluid potassium with blood and brain. Study in normal and Ouabain perfused cats. PMID- 4221488 TI - Effect of quinones on mitochondrial phosphorylation, Pi-ATP exchange, and ATPase activities. II. Vitamin K-2 homologues and K-1 derivatives. PMID- 4221490 TI - Increased brain radiocopper uptake in Wilson's disease. PMID- 4221491 TI - [A case of posterior embryotoxon with buphthalmia and cardiac malformation]. PMID- 4221492 TI - [Toxic neuritis caused by monoamine oxidase inhibitors]. PMID- 4221493 TI - The handicapped child and the law. PMID- 4221494 TI - Effect of heavy water D2-O on resistance of plant and animal cells, cell models and proteins to certain denaturing factors. PMID- 4221496 TI - Thrombelastographic patterns produced by fibrinolytic agents incorporated in fibrin. PMID- 4221495 TI - Age changes in content of sulfhydryl groups and adenosinetriphosphatase activity of myosin. PMID- 4221497 TI - Fusimotor function during sleep in unrestrained cats. An account of the modulation of the mechanically and electrically evoked monosynaptic reflexes. PMID- 4221498 TI - Gaps in the nation's services for children. PMID- 4221499 TI - Alpha-rigidity in reserpinized rats. PMID- 4221500 TI - Pediatric dental rehabilitation. PMID- 4221501 TI - Behavioral patterns of the child patient. PMID- 4221504 TI - The role of the public health nurse in the discharge of the handicapped child to the community. PMID- 4221503 TI - [Case study of a crippled child at the Shimada Sanatorium]. PMID- 4221502 TI - A survey of pediatric dentistry in Cincinnati. PMID- 4221505 TI - Food and rehabilitation of the handicapped. PMID- 4221506 TI - [Notes on therapy of acute nonspecific enteropathies]. PMID- 4221507 TI - [Considerations on some clinical and roentgenological similarities in lumbar discopathies]. PMID- 4221508 TI - [Social aspects of Down's syndrome]. PMID- 4221509 TI - [Effect of glutaric and hydroxyadipic dialdehyde on the adenosine triphosphatase activity of various subcellular fractions of the heart and skeletal muscle]. PMID- 4221510 TI - [Adenosine triphosphate and adenosine diphosphate phosphohydrolases in liver microsomes of mice]. PMID- 4221511 TI - Urinary excretion of mucopolysaccharides in normal individuals and in the Marfan syndrome. PMID- 4221513 TI - Optical rotatory dispersion of mucopolysaccharides and mucopolysaccharide-dye complexes. PMID- 4221512 TI - Analysis of mucopolysaccharides in partially aqueous media. PMID- 4221514 TI - A case of idiopathic cavitation of lung demonstrated at the Postgraduate Medical School of London. PMID- 4221515 TI - A possible mechanism for the anti-inflammatory effects of proteolytic enzymes. PMID- 4221516 TI - Selenium and rabbit skeletal muscle aldolase and myosin. PMID- 4221517 TI - A dental service for children with bleeding disorders. PMID- 4221518 TI - Studies in myocarditis. 3. On the frequency and nature of some common symptoms. PMID- 4221519 TI - [Use of a new antiedemic agent in pediatric and orthopedic surgery. Apropos of 54 cases]. PMID- 4221520 TI - The "dimeric acid product" of 1-methyl-1,4-dihydronicotinamide. PMID- 4221521 TI - The effect of ouabain on the hydration and the adenosine triphosphatase activity of the cornea. PMID- 4221522 TI - Hereditary renal disease associated with deafness; Alport's syndrome. PMID- 4221523 TI - Two cases of atypical leukoencephalitis. PMID- 4221524 TI - A contribution to the study of the body axis in mammals with special reference to domesticated dog. PMID- 4221525 TI - The torsion of the roots in human lower molars. PMID- 4221526 TI - Finger patterns and ridge counts of the Dogons. PMID- 4221527 TI - The influence of plasma substitutes on the suspension stability of human blood. PMID- 4221528 TI - Left ventricular enlargement and hypertrophy. A clinical and angiocardiographic study. PMID- 4221529 TI - Mucopolysaccharides in sweat. PMID- 4221530 TI - A gastroenteritis outbreak of Staphylococcus aureus, type 29. PMID- 4221533 TI - [Public health nursing of handicapped children]. PMID- 4221531 TI - [Ocular toxoplasmosis. Apropos of 29 cases illustrating the various clinical and serological forms]. PMID- 4221532 TI - [Some clinico-laboratory data and their comparison with the distribution of acid mucopolysaccharides in cardiac and pulmonary connective tissues. (Preliminary communication)]. PMID- 4221534 TI - [Demonstration of Arthus reactions in tissue of the cervix of monkeys immunized against seminal fluid]. PMID- 4221535 TI - Lymphoblast transformation in sulphonamide sensitivity. PMID- 4221536 TI - The effect of ovarian hormones on the sulphomucopolysaccharides of the uterus. PMID- 4221537 TI - On the histochemical nomenclature for sialomucins. PMID- 4221538 TI - [Flurandrenolone-iodochlorhydroxyquinoline combination in dermatologic topical use]. PMID- 4221540 TI - [The epidemiologic chain]. PMID- 4221539 TI - [Clinical criminology in the military services]. PMID- 4221541 TI - [Blast injuries. Problems of anesthesia and reanimation]. PMID- 4221542 TI - [Remote complications of amebiasis-disease in career military men. Apropos of 350 cases]. PMID- 4221543 TI - [The microcirculation during traumatic shock]. PMID- 4221544 TI - [Traumatic lesions of the duodeno-pancreas]. PMID- 4221545 TI - [The phosphatases of nerve tissue]. PMID- 4221546 TI - [Antibiotic therapy in septicemic states. (Critical review and analysis of 150 cases)]. PMID- 4221547 TI - The dental management of the physically handicapped child. PMID- 4221548 TI - Fatal case of toxic erythema after chlorpropamide (Diabinese). PMID- 4221549 TI - Studies on the biological activity of Rhus striata ("manzanillo"). I. Hemolytic activity. PMID- 4221550 TI - Development of activity of 3 beta-hydroxysteroid dehydrogenase in human fetal tissues and in two anencephalic newborns. PMID- 4221551 TI - Back pain in a young man. PMID- 4221552 TI - The pathogenesis of ocular lesions of infectious canine hepatitis. II. Experimental ocular hypersensitivity produced by the virus. PMID- 4221553 TI - [Experience with "buried" flat skin flaps]. PMID- 4221555 TI - [Fundus flavimaculatus]. PMID- 4221554 TI - [Current status and prospects of training in the field of pedodontics]. PMID- 4221557 TI - [Oculopalpebral problem of peripheral facial paralysis]. PMID- 4221556 TI - [Pathogenesis and treatment of ocular hypertension in exophthalmos due to arteriovenous aneurysm]. PMID- 4221558 TI - [Our ancestors, the Gallo-Roman ophthalmologists]. PMID- 4221559 TI - Metabolic processes in skin. PMID- 4221560 TI - The effect of progesterone on the sebaceous glands of the rat. PMID- 4221561 TI - Periodicity of S35 uptake in rat femurs. PMID- 4221562 TI - Similar cytological effects of hydroxylamine and 5-FUDR, agents with different modes of action. An analysis of chromosome breakage. PMID- 4221564 TI - Impetigo in the Waikato. PMID- 4221563 TI - Psychologic factors in backache. PMID- 4221565 TI - Basophilic leucocytes and Hashimoto's thyroiditis. Skin reaction upon intradermal injection of thyroid extract studied by skin window technique. PMID- 4221566 TI - [Prevention and indemnification of allergic occupational diseases]. PMID- 4221567 TI - New help for the severely retarded and emotionally disturbed child. PMID- 4221568 TI - [Boring of the Haversian canals]. PMID- 4221569 TI - [Nonosteogenic fibromas]. PMID- 4221570 TI - [New results and technical complements of uncusectomy in the treatment of radicular and arterio-vertebral complications of cervical arthroses]. PMID- 4221571 TI - [Diagnosis of cervical disk hernias by discography and their surgical treatment]. PMID- 4221572 TI - [Indications and results of Hoffmann's external fastener in open leg fractures. (Statistics of 82 cases)]. PMID- 4221573 TI - [Presentation of an apparatus for measurement of scoliotic gibbosities]. PMID- 4221575 TI - [The treatment of enteritis in infants with the kanamycin-sulfadiazine iodochloroxy-quinolein drug combination]. PMID- 4221574 TI - [Prosthesis for tibial amputation with adaptable socket]. PMID- 4221576 TI - [Otospongiosis or posttraumatic stapedial ankylosis?]. PMID- 4221577 TI - [Recent advances in epidemiology]. PMID- 4221578 TI - [Present status of rural water supply programs in Latin America]. PMID- 4221579 TI - [Human leptospirosis in Haiti]. PMID- 4221580 TI - [The teaching of the social sciences in medical schools]. PMID- 4221581 TI - [On the application of tuberculin tests in epidemiological practice]. PMID- 4221582 TI - [A new combined vaccine against Bordetella parapertussis, diphteria, tetanus and pertussis]. PMID- 4221583 TI - [A study on the occurrence of pertussis and parapertussis among the population of the Svitavy district, and the experience with these diseases in the district]. PMID- 4221584 TI - [The use of chromatography in the preparation of Tahyna and Calovo arbovirus antigens]. PMID- 4221585 TI - [Advantages of the interlock mask in comparison with the "Svedia" mask]. PMID- 4221586 TI - [A contribution on the current state of sensitivity of Escherichia colidyspepticum to certain antibiotics]. PMID- 4221587 TI - Essential hypertension. A twenty-year follow-up study. PMID- 4221588 TI - [The plan of choice for the radiologic examination of kyphoscolioses]. PMID- 4221589 TI - [Recurrent luxation of the shoulder and glenoid labrum lesions]. PMID- 4221590 TI - [Aneurysmal bone cysts. Diagnostic and therapeutic problems. Apropos of 5 cases]. PMID- 4221591 TI - [A simple means of lengthening the ulna. (Apropos of 6 cases Kienbock's disease)]. PMID- 4221592 TI - [Fasciculated nail for centromedullary nailing]. PMID- 4221593 TI - Helpful diagnostic clues for differentiation of atopic dermatitis from seborrheic dermatitis. PMID- 4221595 TI - [Traditional obstetrics in rural regions]. PMID- 4221594 TI - [The method of gel precipitation in the diagnosis of rabies]. PMID- 4221596 TI - [The scientific physician and the "healer"]. PMID- 4221597 TI - Can pedodontics and orthodontics be combined in practice? PMID- 4221598 TI - Pedodontic care for the deaf and blind. PMID- 4221599 TI - Diabetes screening with Dextrostix in an industrial plant. PMID- 4221600 TI - New AMWA president--1966. PMID- 4221601 TI - [Marfan's syndrome. Clinical and biological aspects with particular attention to the existence of a mucopolysacchariduria]. PMID- 4221602 TI - [Rigidity and Huntington's chorea. The infantile form of Huntington's disease. (Study of an anatomo-clinical case)]. PMID- 4221603 TI - [Skin diseases among agricultural workers in flax and sugar beet of areas]. PMID- 4221604 TI - The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods. PMID- 4221605 TI - Studies on swelling-shrinkage and oxidative phosphorylation of liver mitochondria of rat fed on 3'-methyl-4-dimethylaminoazobenzene. PMID- 4221606 TI - Biosynthesis of isovalthine. PMID- 4221607 TI - On the relation between the fatty acid composition and the swelling rate in rat liver mitochondria. PMID- 4221608 TI - On the carbon origin of isovaleric acid residue of urinary isovalthine. PMID- 4221609 TI - Attempts to cultivate Mycobacterium lepraemurium in cell-free media. PMID- 4221610 TI - A study of back cases in an outpatient clinic. PMID- 4221611 TI - Growth of interorbital distance and skull thickness as observed in roentgenographic measurements. PMID- 4221612 TI - [Current problems concerning occupational dermatoses]. PMID- 4221613 TI - Ultrastructure of nasal scleroma (emphasizing the fine structure of Klebsiella rhinoscleromatis within the lesion). PMID- 4221614 TI - Mechanism of melanophore dispersion. II. Stimulus-reaction-recovery and receptor problem. PMID- 4221615 TI - [Comparison of effects of thymine deficiency induced by 2 different antimetabolites, 5-fluorodeoxyuridine and aminopterin, on the macromolecular metabolism of a pathogenic strain of Staphylococcus aureus]. PMID- 4221616 TI - Exchangeable water, sodium and chloride in the skin of mice. PMID- 4221618 TI - Endocrine effects on rat cardiac myofibrillar ATPase. PMID- 4221617 TI - The effect of Sr2+ on swelling and ATP-linked contraction of mitochondria. PMID- 4221619 TI - [Sanitary engineering education in Venezuela]. PMID- 4221620 TI - [A simple device for the cultivation of cells in suspensions]. PMID- 4221621 TI - [Effect of chemical thyroidectomy, thyroid extract therapy and of the thyreotropic hormone on the content of mucopolysaccharides in the blood of rabbits]. PMID- 4221622 TI - Severe respiratory failure. The diagnosis and management of 37 cases. PMID- 4221623 TI - Clinical relapse in early syphilis: unusual skin lesion following inadequate treatment. PMID- 4221624 TI - [Generalized erythroderma with total agranulocytosis after a hypoglycemic sulfonamide]. PMID- 4221625 TI - [Analgesic treatment of lumbar sciatica]. PMID- 4221627 TI - Abdominal electromyography during micturition. PMID- 4221626 TI - A histochemical and electron microscopic study of skeletal muscle in a case of Pompe's disease (glycogenosis II). PMID- 4221628 TI - Heart size and prognosis in myocardial infarction. PMID- 4221629 TI - Dietary production of myocardial fibrosis in the rat. PMID- 4221630 TI - Clinical pathologic conference. PMID- 4221631 TI - [Correlation of the clinical and pharmaco-dynamic effects of Niamid in the treatment of severely mentally retarded children]. PMID- 4221632 TI - [To what questions can spinal radiography give an answer?]. PMID- 4221633 TI - Disability under Social Security: total-temporary impairments now entitled to benefits. PMID- 4221634 TI - Increase of serum beta-glucuronidase activity in human diabetes mellitus. PMID- 4221635 TI - Intramyocardial lesions in patients dying suddenly and unexpectedly. PMID- 4221636 TI - The handicapped child and the family. PMID- 4221637 TI - [Some considerations on the malignant desmoid]. PMID- 4221638 TI - Separation of adenosine triphosphatase of HK and LK sheep red cell membranes by density gradient centrifugation. AB - Membrane fragments from high potassium (HK) and low potassium (LK) sheep red cells were separated by density gradient centrifugation. Three preparations were studied: (1) HK membranes sonicated for 20 minutes, (2) HK membranes sonicated for 3 minutes, and (3) LK membranes sonicated for 3 minutes. The adenosine triphosphatase (ATPase) activity in the maximally disrupted preparation (1) was not sensitive to Na + K and was recovered in relatively small but heavy (specific gravity 1.19) fragments which made up no more than 8 per cent of the total membrane. Both Na + K-sensitive (S) and Na + K-insensitive (I) ATPase activity were found in the more gently broken up preparations (2) and (3) but the ratio of S- to I-ATPase was much greater in HK than in LK membrane fragments. S-ATPase activity in preparation (2) was about 50 per cent that observed in HK membranes prior to sonication. S-ATPase activity was recovered from the density gradient in relatively large but light (specific gravity 1.10) fragments. As was the case with the maximally disrupted preparation (1), I-ATPase activity in both preparations (2) and (3) was recovered in small but heavy (specific gravity > 1.20) fragments. The possibility that sensitivity of sheep red cell membrane ATPase to Na + K depends on the association between units containing the enzyme(s) and large, light, phospholipid-containing components is discussed. PMID- 4221639 TI - Thymidine incoporation into mammalian strain L-cells after the action of 5 fluorodoxyuridine and the effect of uracil. PMID- 4221640 TI - Let's dress the disabled for living. PMID- 4221641 TI - Mongoloids, twins and tolerance. PMID- 4221642 TI - [Culture in vitro of non-incubated bird blastoderms and development of isolated parts]. PMID- 4221643 TI - [Action of melanophoric hormones (alpha and beta MSH) on the gonads of the male guinea pig]. PMID- 4221645 TI - [Aldactone and osmoregulation in the eel]. PMID- 4221644 TI - [Effects of an inhibitor of corticosteroid biosynthesis, metopyrone, on the quantities of adrenaline and noradrenaline present in the adrenals of the rat]. PMID- 4221646 TI - [Feminizing effect of an LH preparation in the male viviparous lizard embryo]. PMID- 4221647 TI - [On the cytotoxicity of tetrodotoxin]. PMID- 4221648 TI - [Estimation of the quantity of glucose utilized by the ewe mamma during the 1st 3 months of lactation]. PMID- 4221649 TI - [The adapto-electroretinogram of the rabbit during experimental retinosis induced by sodium iodate]. PMID- 4221650 TI - [Study of the sero-agglutination of polystyrene particles loaded with histamine in anaphylaxis in guinea pigs]. PMID- 4221651 TI - [The sero-agglutination of serotonin fixed on polystyrene latex in humoral allergy]. PMID- 4221652 TI - [Immunochemical study of the hemoglobin (erythrocruorine) of Arenicola marina L]. PMID- 4221653 TI - [Contraction of muscle during its passive shortening in certain pathological states]. PMID- 4221654 TI - [Effect of a chronic treatment by procaine on nervous excitability in rats. Comparison with the action of an acute treatment]. PMID- 4221655 TI - [Exaggerated development of obstetrical toad tadpoles, intact or deprived of their pituitary glands, and subjected to a treatment by prolactin]. PMID- 4221656 TI - [Study of the urinary elimination of several ions in the golden hamster (Mesocricetus auratus Waterhouse)]. PMID- 4221657 TI - [Action on the Oddi's sphincter of the guinea pig of an analgesic, a neuroleptic and their combination]. PMID- 4221658 TI - [The effects of estradiol injected during ontogenesis on the differentiation of the vagina and uterus in mice]. PMID- 4221659 TI - [Action of illuminating gas and Lacq gas on the nervous system of the bird embryo]. PMID- 4221660 TI - [Action of anesthetic infiltration of the carotid sinus in dogs and rabbits with different arterial pressure values]. PMID- 4221661 TI - [Relative importance of the cardiomoderator influence on the Keith and Flack and Tawara nodes in the dog]. PMID- 4221662 TI - [The electroretinogram in man: organicity of the e waves or oscillatory potentials; their relation to the photopic system]. PMID- 4221663 TI - [Development of adenosine triphosphatase and glucose-6-phosphate dehydrogenase activities in the mouse thymus during growth]. PMID- 4221664 TI - [Apropos of the regeneration of retinal purple in the enucleated cattle eye]. PMID- 4221665 TI - [Localization of the hemagglutinin of the egg of Phallus impudicus L. ex Fr]. PMID- 4221666 TI - [Recent research on the antagonism between estrogen and progesterone in the female Wistar rat]. PMID- 4221667 TI - [Observation by electron microscopy of the anterior lobe of the human embryonal pituitary in the 3d month of intrauterine life]. PMID- 4221668 TI - [Is the regulatory level of internal temperature modified by muscular work?]. PMID- 4221669 TI - [Oxygen consumption and gregariousness in the newborn rat]. PMID- 4221670 TI - [The value of various forms of acid-soluble phosphorus in the heart, liver and muscle of rats subjected to a barometric depression (6500 m simulated altitude)]. PMID- 4221671 TI - [Respiratory intensity of the normal muscle and denervated muscle of the frog]. PMID- 4221673 TI - [Organization of the system responsible for phase activity during paradoxal sleep]. PMID- 4221672 TI - [Elective suppression of paradoxal sleep in the cat by monoamine oxidase inhibitors]. PMID- 4221674 TI - [On the relationships existing between oxygen partial pressure in the hemolymph and the activity of the isolated snail ventricle]. PMID- 4221675 TI - [Proteins with hemopexic properties in the carp (Cyprinus carpio). Their characterization by electrophoresis and gel filtration]. PMID- 4221676 TI - [Biochemical research on the inactivation of 5-hydroxytryptamine at the level of the heart in the mollusca Helix pomatia, Buccinum undatum, Venus mercenaria and Mya arenaria]. PMID- 4221677 TI - [Limit of the influence of somatotropic hormone of the gonadotropic activity of urinary extracts]. PMID- 4221678 TI - [Effects of beryllium on the synthesis of nuclear proteins and desoxyribonucleic acid in fibroblasts cultivated in vitro]. PMID- 4221679 TI - [Conditions for producing the Shwartzman phenomenon in the newborn rabbit]. PMID- 4221680 TI - [Diminution of the serotonin content of the blood in the irradiated rabbit]. PMID- 4221681 TI - [The ultrastructure of the nucleolus of the cat oocyte and its involution during the meiotic prophase]. PMID- 4221682 TI - Influences of protamine on the na+, K+-dependent ATPase and on the active transport processes of potassium and of L-DOPA into brain slices. PMID- 4221683 TI - On the action of strophanthin G. PMID- 4221684 TI - Connection between membrane adenosine triphosphatase activity and potassium transport in erythrocyte ghosts. PMID- 4221685 TI - Evaluation of the method of rivanol precipitation of [35S] sulphated mucopolysaccharides present in the material obtained from a small group of cells. PMID- 4221686 TI - Connective and supporting tissues: mucopolysaccharides of connective tissues. PMID- 4221687 TI - Chromosome abnormalities in a patient suffering from Huntington's chorea. PMID- 4221688 TI - [Separation and determination of nucleosides in the presence of nicotinamide and thiamine monophosphoric ester]. PMID- 4221689 TI - The effect of digitalis on the renal tubular transport of glucose in normal and in heartless dogs. PMID- 4221691 TI - [Psychomotor re-education and school maladjustment]. PMID- 4221690 TI - The care of the physically handicapped child. PMID- 4221692 TI - [Motor handicapped and school maladjustment]. PMID- 4221693 TI - Granulopoiesis in Down's syndrome. PMID- 4221694 TI - A new radiographic finding in mongolism. PMID- 4221695 TI - [Pathogenesis and clinical varieties of lumbago]. PMID- 4221696 TI - [Do connections exist between penicillin G resistance, phage type, antigen structure and enzyme spectrum of pathogenic staphylococci?]. PMID- 4221697 TI - Antimitotic action of cornin as a biologically active polypeptide. II. Physiological effects of cornin on dividing cell. PMID- 4221698 TI - Immunochemical analysis of antigenic properties of human stomach cancer. PMID- 4221699 TI - Antimitotic action of cornin as a biologically active polypeptide. I. Biochemical properties of cornin. PMID- 4221700 TI - A histotopochemical study of the parathyroid gland of the albino rat. PMID- 4221701 TI - [Histological and histochemical investigations on the stomach of the swamp beaver Myocastor coypus Mol]. PMID- 4221702 TI - Acne: tetracyline or not? PMID- 4221703 TI - [Corticoids in eczema]. PMID- 4221704 TI - [Unusual pulmonary radiologic findings in cardiac decompensation]. PMID- 4221705 TI - The enzymic activity of the outer shell of Lactobacillus arabinosus. PMID- 4221706 TI - We're too fat. PMID- 4221707 TI - What should we tell the patient? PMID- 4221708 TI - Obesity and the emotions. PMID- 4221709 TI - Brdicka serum filtrate reaction applied to normal and cancerous menstrual fluids. PMID- 4221710 TI - Diaphragmatic hernia in a premature infant. PMID- 4221711 TI - Neurologic manifestations accompanying burns (burn encephalopathy). PMID- 4221712 TI - Individuality of intellectual development. PMID- 4221713 TI - The impact of disability on the child. PMID- 4221714 TI - The abnormal child: his impact on the family. PMID- 4221715 TI - Lack of correlation between natriuretic activity and inhibition of renal Nak activated ATPase. PMID- 4221716 TI - Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues. PMID- 4221717 TI - Study of employment of 222 men with spinal cord injury. PMID- 4221719 TI - [Karyometric examination of nerve cells adapted to an enlarged innervation zone]. PMID- 4221718 TI - [Effect of acridine orange and safranin on kinetics of the enzyme-substrate complex of actomyosin]. PMID- 4221721 TI - [Effects of heated blood and cystamine on the blood circulation of the intestine homotransplanted to the neck in dogs]. PMID- 4221720 TI - [Electrophoretic study of the action of different sulfated polysaccharides on peptic proteolysis]. PMID- 4221722 TI - Golden anniversary--golden opportunity. PMID- 4221723 TI - Psychomotor abilities of familial, brain-injured and mongoloid retarded children. PMID- 4221724 TI - The chances of reducing the incidence of skin infections of the newborn in a maternity hospital. PMID- 4221725 TI - [Study of behavior of free plasmatic corticosteroids after load with deyhdroepiandrosterone in eucrinic subjects]. PMID- 4221726 TI - [An epidemic pruriginous dermatosis. Infestation by Pediculoides ventricosus. The acariasis of ports and wharfs]. PMID- 4221727 TI - Special clothing for the handicapped. Review of research and resources. PMID- 4221728 TI - [A new treatment of hepatic metastases]. PMID- 4221729 TI - Comparative antibiotic sensitivity studies in pustular acne vulgaris, 1954 and 1962. PMID- 4221730 TI - [Fibrinolysis and plasmin]. PMID- 4221731 TI - [Some notes on assaying the plasmin system]. PMID- 4221732 TI - [Clinical and cytogenetic study of a case of mosaicism. Form of a normal line and a trisomic line for a chromosome of the 16-18 group]. PMID- 4221735 TI - Problems of terminology in endocrinology. PMID- 4221734 TI - Studies on the effect of hypophysectomy and of partial hepatectomy on the aminoacid incorporating system from rat liver. PMID- 4221736 TI - Regulation of protein synthesis: an alternative to the repressor-operator hypothesis. PMID- 4221738 TI - Reflectometry of the skin in Dogons. PMID- 4221737 TI - A radioautographic and radiometric analysis of the influence of parathyroid extract on the proline binding capacity of cultivated mouse radius rudiments. PMID- 4221739 TI - Progressive brachycephalization: reproduction and headform in the Netherlands. A preliminary report. PMID- 4221740 TI - "Doubling" of the palatal root in the second and third upper molars. PMID- 4221741 TI - [The mandibular mediodens]. PMID- 4221742 TI - The deposition of radioactive Ba and Sr in the aortic wall. PMID- 4221743 TI - Hemolymph protein and amino-acid composition as influenced by the corpus allatum in Locusta migratoria migratorioides (r. & f.). PMID- 4221744 TI - Abdominal-wall hematomas. PMID- 4221745 TI - [Plastic surgery, for esthetic purposes, of the abdominal wall]. PMID- 4221746 TI - Acid mucopolysaccharides in electron microscopy. The use of the colloidal iron method. PMID- 4221748 TI - A comparison of the phosphorus metabolism of intact squid nerve with that of the isolated axoplasm and sheath. PMID- 4221747 TI - Phosphorus metabolism of intact crab nerve and its relation to the active transport of ions. PMID- 4221749 TI - [Studies in the rat on the problem of the diabetogenic effect of saluretics]. PMID- 4221751 TI - S35 taurine metabolism in normal and mongoloid individuals. PMID- 4221750 TI - [Experiments on the action of paraoxon on the respiratory and vagus centers and the effect of various antidotes]. PMID- 4221752 TI - Concentrations of uric acid in the sweat of control and mongoloid children. PMID- 4221753 TI - Histochemical and histoenzymological studies on the growing cartilage in the Turner's syndrome. PMID- 4221754 TI - Congenital malformations produced in chickens by fluorinated pyrimidines. PMID- 4221755 TI - Massive neurofibrosarcoma of the anterior abdominal wall. PMID- 4221757 TI - [The surgical treatment of rhinophyma]. PMID- 4221756 TI - Notes from a visit to the Soviet Union: treatments and studies of alcoholism; education about alcohol; drinking in Georgia. PMID- 4221758 TI - IUPAC-iub Commission on Biochemical Nomenclature. Tentative rules. Trivial names of miscellaneous compounds of importance in biochemistry. PMID- 4221759 TI - Experimental tetracycline labeling in avian osteopetrosis. AB - Osteopetrosis was experimentally produced and lesion development in time was studied by fluorescent illumination of tetracycline labels in the bone. Bones from birds 84, 115, 186 and 354 days of age were examined by ground section under ultraviolet light. Periosteal activity of the tibia and femur was present in normal bones at 84 days of age but had stopped at 115 days. Focal periosteal activity of osteopetrotic lesions was present at 186 days but not at 354 days of age. Slight endosteal activity of osteopetrotic bones was present at 354 days of age. Osteopetrotic bone formed at a rate of 1.26 mm. per week or 6 times faster than normal bone in some of these lesions. Tetracycline diffused throughout the 354-day-old osteopetrotic lesion but not normal compact bone indicating that the osteopetrotic bone is porous and spongy. PMID- 4221760 TI - Amyloidosis in captive anseriformes. AB - During the period 1945-1962, percentage deaths of anserine birds (ducks, geese and swans) did not vary remarkably from year to year even though the population has more than quadrupled during the same period. The number of deaths with amyloidosis has increased significantly even though the death rate did not change. The number of deaths due to tuberculosis, mould, renal diseases, hepatitis and infection accompanied by amyloidosis also increased, especially during the second half the study period. Cases of known secondary amyloidosis accounted for 71.4% whereas 28.6% of the remaining cases were classified as "doubtfully" primary. Sites of deposition amyloid in the two categories were the same and it has never been observed in the heart. The amyloid deposits in the birds did not differ from those in man when examined by number of histochemical methods. PMID- 4221761 TI - Surface temperatures of avian osteopetrotic bones. AB - Body temperatures and surface temperatures of metatarsal bones were recorded in normal and osteopetrotic chickens. Osteopetrotic lesions were 6.5 F warmer than normal bones but there was no corresponding increase in body temperature at a given environmental temperature. This indicates that the temperature elevation in the osteopetrotic lesion is a local phenomenon and not a systemic response. This also supports earlier observations that osteopetrotic bones feel warmer to the touch than normal bones. PMID- 4221762 TI - Production of antibodies in the mammary gland with especial reference to virus neutralizing antibody. PMID- 4221763 TI - [Our experience with the Bernard's currents therapy (Diadynamik) in neurology]. PMID- 4221764 TI - [Characteristics of the microflora of the E. coli group in water reservoirs of Southeastern Turkmenia]. PMID- 4221765 TI - [Data on the examination of the organ of vision in workers of industrial plants and machine operators in Andizhan]. PMID- 4221766 TI - Volunteers blaze a trail. PMID- 4221767 TI - Down's syndrome with unusual karyotype and thyroid autoantibodies. PMID- 4221769 TI - [Investigations on backache in our agricultural area]. PMID- 4221768 TI - [Histochemistry of the mucopolysaccharides of the gastric plaques of intestinal metaplasia]. PMID- 4221770 TI - [Some problems concerning the medical evaluation of working capacity by the VKK and the VTEK]. PMID- 4221771 TI - Enzyme activities and maximal rates of glycolysis in anaerobic myocardium. PMID- 4221772 TI - A comparison of two antiseptic and steroid creams, illustrating the importance of an "order effect" in such trials. PMID- 4221773 TI - Genetic interference and recombination in phage T4: the role of heterozygotes. PMID- 4221774 TI - Study of mechanisms which preserve blood fluidity and the effect of their inhibition on thrombogenesis. PMID- 4221775 TI - [Electron microscopic investigations on the structure of trout musculature and the localization of acid ATPase during rigor mortis]. PMID- 4221776 TI - Clinical studies with systemic administration of antimetabolites of pyrimidine nucleosides in viral infections. PMID- 4221778 TI - The halt and the whole: thoughts on adaptation. PMID- 4221777 TI - The use of metabolic inhibitors in studies on the mode of replication of vaccinia virus. PMID- 4221779 TI - Combined oral, topical and surgical treatment of onychomycosis. PMID- 4221780 TI - Improved griseofulvin therapy for tinea pedis. PMID- 4221783 TI - Civil actions for damages versus workmen's compensation benefits. PMID- 4221781 TI - The mechanism of calcium and magnesium uptake from sea water by a marine bacterium. PMID- 4221782 TI - Backache in industry. PMID- 4221784 TI - Management of atopic dermatitis. PMID- 4221785 TI - Office management of acne vulgaris. PMID- 4221787 TI - [Congenital aplasia of the abdominal musculature]. PMID- 4221786 TI - Hexosamine content of callus tissue. PMID- 4221788 TI - A multidisciplined evaluation clinic for the child with a handicap. A summary of the first year's activities. PMID- 4221790 TI - Biochemical study of anti-inflammatory and anti-arthritic properties of glycyrrhetic acid. PMID- 4221789 TI - Biochemical properties of anti-inflammatory drugs. VI. The effects of chloroquine (resochin), mepacrine (quinacrine) and some of their potential metabolites on cartilage metabolism and oxidative phosphorylation. PMID- 4221792 TI - [Radiologic observations on lumbalgias]. PMID- 4221791 TI - Molecular mechanisms of genetic recombination of bacteriophage. V. Two kinds of joining of parental DNA molecules. PMID- 4221793 TI - [Contribution to the knowledge of choreal psychoses. Choreal "morbidity" in study of 17 patients with familial chronic chorea]. PMID- 4221794 TI - [Description of a case of partial congenital atrophy of the abdominal musculature]. PMID- 4221795 TI - [Electrophoretic behavior of blood lipoprotein fractions in the child affected by seborrheic eczema]. PMID- 4221796 TI - [Results of a controlled trial of indomethacin in rheumatology]. PMID- 4221797 TI - [Research on modifications of isolated muscle chronaxy. I. Action of bismuth ions]. PMID- 4221798 TI - [Late results of conservatively treated congenital hip dislocation. II. 40 years after repositioning]. PMID- 4221799 TI - [On the morphology and pathogenesis of primary congenital coxa vara and its relationship to the so-called femur defect]. PMID- 4221800 TI - [Experiences in the treatment of Perthe's dislocation with special reference to the use of anabolic drugs]. PMID- 4221801 TI - [Imhauser osteotomy for epiphysiolysis]. PMID- 4221802 TI - [Contribution on a partial sagittal cleft of the vertebral body]. PMID- 4221804 TI - [A contribution to the surgical treatment of Osgood-Schlatter disease]. PMID- 4221803 TI - [A contribution on osteitis condensans ilii]. PMID- 4221805 TI - [Loffler's operation of the knee joint]. PMID- 4221806 TI - [The treatment of spastic paralysis using double osteotomy]. PMID- 4221807 TI - [On the treatment and care of bilateral phocomelic ectromelia of the lower extremities]. PMID- 4221809 TI - [On the differential diagnosis of tumor diseases: herniated disc--sacral tumor]. PMID- 4221808 TI - [Studies on the maturation of human connective tissue]. PMID- 4221810 TI - [A case of congenital retroisthmic cleft of the vertebral arc]. PMID- 4221811 TI - [On the influence of fixation procedures of the hip upon the growth direction of the femur in rabbits]. PMID- 4221812 TI - [Experimental studies on the problem of the development of scoliosis by a forced faulty posture]. PMID- 4221813 TI - [Phalanx in phalanges]. PMID- 4221814 TI - [A new possibility in the treatment of spontaneous deformity of the femur neck]. PMID- 4221815 TI - [On the rise in the morbidity age in juvenile osteochondrosis of the hip]. PMID- 4221816 TI - [Gustav Albert Wollenberg, in memoriam]. PMID- 4221817 TI - [Sacral pain caused by diminished space of the spinal canal]. PMID- 4221818 TI - [Comparative study on the neuromuscular spindles of the lumbrical muscles in certain mammals and in man]. PMID- 4221819 TI - A model illustrating some aspects of muscle spindle physiology. PMID- 4221821 TI - Diagnosis and surgical correction of combined congenital defects of supra umbilical abdominal wall, lower sternum, and diaphragm. PMID- 4221822 TI - [Left ventricular hypertrophy in left branch block. Vectorcardiographic study]. PMID- 4221820 TI - Studies on the adenosine triphosphatase, calcium uptake and relaxing activity of the microsomal granules from skeletal muscle. PMID- 4221823 TI - Eruption of teeth through the oral mucosa. PMID- 4221824 TI - [Thalassemia in the Azerbaidzhan SSR. (Distribution, clinical aspects and therapy)]. PMID- 4221825 TI - Effect of different steroids on lactating rats. PMID- 4221826 TI - An effect of growth hormone on hexose phosphate metabolism. PMID- 4221827 TI - Identification of a cytopathogenic agent infectious for puppies as a canine herpesvirus. PMID- 4221828 TI - Effect of diisopropyl fluorophosphate on gastric secretion and gastric ATPase. PMID- 4221829 TI - Stimulation of erythrocyte glycolysis by nicotinamide adenylates. PMID- 4221831 TI - [Comparative serological and immunomorphological investigations of the infective and immunization process in experimental brucellosis]. PMID- 4221830 TI - In vitro inhibition of Na+-K+ and Mg2+ ATPases by mono, di and trivalent cations. PMID- 4221832 TI - [Various laboratory investigations in connection with serum therapy of staphylococcal toxicosis in infancy]. PMID- 4221833 TI - [Inhibition of adjuvant-arthritis with lathyrism]. PMID- 4221834 TI - Immunological study of rabbit cysticercosis. I. The suitability of agar gel diffusion precipitation and indirect haemagglutination tests. PMID- 4221835 TI - [Remarks on the methodology of the complement fixation reaction]. PMID- 4221837 TI - Correction of the von Krogh equation. PMID- 4221836 TI - [On hemoglobin polymorphism in the horse]. PMID- 4221838 TI - Studies on biochemical and metabolic changes of rat and guinea-pig skin following congelation. PMID- 4221839 TI - Hormone assay studies in patients with anorexia nervosa. PMID- 4221840 TI - The protective influence of substances upon the antimitotic effect of epinephrine and its metabolites in human cell cultures. PMID- 4221841 TI - Preparation--properties of A Na+ + K+-activated MgATPase in the rabbit auricle. PMID- 4221843 TI - Medical treatment of hypertension. PMID- 4221842 TI - Interactions of positive inotropic agents and metabolites on the rat ventricle strip. PMID- 4221844 TI - Study of the UV-induction of mutations in bacteria. PMID- 4221845 TI - Brow presentation. PMID- 4221846 TI - Iatrogenic acute anemia: primaquine sensitivity. PMID- 4221848 TI - Renal glycosuria. PMID- 4221847 TI - Hepatitis. PMID- 4221849 TI - A simulation study of mammalian phosphofructokinase. PMID- 4221850 TI - The glycosaminoglycans of the early stage of fracture repair. PMID- 4221851 TI - The glycosaminoglycans in a pseudarthrosis femoris. PMID- 4221852 TI - [Mucopolysacchariduria and syndrome of Marfan]. PMID- 4221853 TI - Dental care for the special patient. (Handicapped--chronically ill--aged). PMID- 4221854 TI - Common nondiscogenic back disorders. PMID- 4221855 TI - What every doctor should know about workmen's compensation. PMID- 4221856 TI - [Marcel Delepine (1871-1965)]. PMID- 4221857 TI - [Study of cancerous blood cells by leukoconcentration]. PMID- 4221858 TI - [A naturalist in the country. 1. The birds. 2. The garden. 3. The trees]. PMID- 4221859 TI - [On the role of mechanisms of genetic regulation in virus multiplication]. PMID- 4221860 TI - The radiological manifestations of the initial phases of rheumatic carditis in childhood. PMID- 4221861 TI - Diaphragm movements and the diagnosis of diaphragmatic paralysis. PMID- 4221862 TI - An investigation by electron microscopy of the nucleoside phosphatase activity of amphibian and mammalian erythrocytes. AB - Amphibian and mammalian blood was washed in isotonic saline, fixed in glutaraldehyde, and then stained in the ATPase medium of Wachstein and Meisel. The blood cells were subsequently postfixed in osmium tetroxide, embedded in epoxy resins, and studied by electron microscopy. The plasma membranes of amphibian erythrocytes, from the newt Triturus cristatus and the frog Rana esculenta, were stained after incubation in media containing ATP or ADP as substrates, but were unstained after incubation in media containing AMP or sodium beta-glycerophosphate. The addition of 0.001 M ouabain to ATP-containing media did not inhibit the staining of the plasma membranes, but the omission of Mg(++) ions from the medium inhibited staining. The plasma membranes of rat and rabbit erythrocytes were never stained after incubation in any of the media used. PMID- 4221863 TI - The use of short-induction nitrous oxide and oxygen with penthrane; a new concept in pediatric oral surgical anesthesia. PMID- 4221864 TI - [Enemies of the skin]. PMID- 4221865 TI - [On the problem of acariasis]. PMID- 4221866 TI - [Early cutaneous changes under the influence of industrial solvents]. PMID- 4221867 TI - [Seasonal variations of pyoderma and staphylococcal flora of the normal skin in Alma-Ata]. PMID- 4221868 TI - [Current status and prospects for the eradication of infectious forms of syphilis in Kazakhstan]. PMID- 4221869 TI - [Occupational dermatitis and their prevention in workers of a building material establishment]. PMID- 4221870 TI - Treatment of acne vulgaris with Secomat -S lotion. PMID- 4221871 TI - Staphylococcal enterotoxin. PMID- 4221872 TI - Biological attributes of staphylococcal cell walls. PMID- 4221873 TI - Observations of the staphylococcal nasal carrier state. PMID- 4221874 TI - Patterns of transmission of staphylococci. PMID- 4221875 TI - Intracellular phosphate release by the Na+-K+-activated membrane ATPase. PMID- 4221876 TI - Reduction of dynamic sensitivity of primary muscle spindle endings in experimental tremor. PMID- 4221877 TI - A method for turbidimetric measurement of heparin: its application to the estimation of heparin in aortic tissue. PMID- 4221878 TI - Aortic acid mucopolysaccharides and collagen in scorbutic guinea pigs. PMID- 4221879 TI - [Organization of the Central Hospital of the Kant Region of the Kirghiz SSR]. PMID- 4221880 TI - [Current status of medical and industrial sanitary services in the coal mining, ore mining and petroleum industry of the Osh Region]. PMID- 4221881 TI - [Anastomosis formation between spleen and abdominal wall following UV radiation in the rat]. PMID- 4221882 TI - Increase in uric acid biosynthesis produced by 2-substituted thiadiazoles. PMID- 4221883 TI - Separation and characterization of delta-5-3-hydroxy-C19-steroids by thin-layer chromatography. PMID- 4221885 TI - [Occupational traumatism in construction workers of the Karaganda mettalurgic plant]. PMID- 4221884 TI - Acid mucopolysaccharides in the oral epithelium. PMID- 4221886 TI - [Iatrogenic dermopathies]. PMID- 4221887 TI - Management of skin problems in the adolescent. PMID- 4221888 TI - Chemical analysis and biological activities of fatty acids from the liver of x ray irradiated rabbit, the antitumor agent so-called OX. PMID- 4221890 TI - Mechanism of induction of anisocytosis. PMID- 4221889 TI - [Clinico-experimental research on the effect of triparanol (TP) in arteriosclerosis]. PMID- 4221891 TI - Cellular antibody in mice bearing Ehrlich cancer. I. A quantitative study on antitumor activity of cellular antibody in vitro. PMID- 4221892 TI - [Erythroderma. Malignant reticulosis. Sub-leukemia]. PMID- 4221893 TI - Cytochemical studies of adenosine triphosphatase activity in the sarcoplasmic reticulum. PMID- 4221894 TI - [The treatment and control of patients with acne]. PMID- 4221895 TI - Factors influencing activation of phosphofructokinase. PMID- 4221896 TI - Unbelievable medico-legal adjudications. PMID- 4221897 TI - The influence of heating on the morphology and photochemical activity of isolated chloroplasts. PMID- 4221898 TI - Preparation of rabbit muscle myosin or actomyosin free of 5'-adenylic acid deaminase. PMID- 4221899 TI - The effect of lipids on enzyme levels in beating rat heart cells. PMID- 4221900 TI - Left ventricular hypertrophy in chronic bronchitis. PMID- 4221901 TI - [Dislocating fractures of the upper ankle joint. Influence of direction and extent of displacement upon the repositioning]. PMID- 4221902 TI - [On the treatment of joint fractures of the heel bone]. PMID- 4221903 TI - [On the after care of operated bone fractures]. PMID- 4221904 TI - [Joint mouse following meniscectomy]. PMID- 4221905 TI - [Osteomyelitis and accidents]. PMID- 4221906 TI - The Graham-Steell murmur re-evaluated. PMID- 4221907 TI - [On the incidence of the various phage groups and lysotypes of pathogenic staphylococci within a surgical clinic]. PMID- 4221909 TI - Extracts from a lecture delivered by A. Withnell, Esq., B.Sc., M.D., D.P.H. to dental surgery assistants in the employment of the Staffordshire County Council School's Health Service. PMID- 4221908 TI - Anomalies of the origin of coronary arteries. (Special reference to single coronary artery). PMID- 4221910 TI - Hog cholera. V. Demonstration of the antigen in swine tissues by the fluorescent antibody technique. AB - The fluorescent antibody technique was employed to detect hog cholera virus in tissue sections of various organs from experimentally infected swine. The method proved to be highly sensitive and infection could be detected in these animals as early as three days after inoculation with the virus. Best results were obtained when tissues were collected from young animals in advanced disease rather than from sows or from pigs in the early febrile phase. Tonsil, spleen and lymph node were the tissues of choice and were most satisfactory when removed from freshly killed animals rather than from those that had died. PMID- 4221911 TI - Progressive myelopathy in a dog caused by thorium dioxide. AB - A study of the use of Thorotrast as a contrast media in myelograms in dogs is presented, indicating that the material introduced into the cerebro-spinal fluid, will become permanently associated with the meninges, leading to the development of myelopathy. PMID- 4221912 TI - The physiopathological changes in synovial fluid in arthritic swine. AB - There was produced with Ery. rhusiopathiae a rheumatoid-like arthritis in swine, which passed successively through acute, sub-acute and chronic stages. This was typically a non-suppurative proliferative change with concurrent changes in the joint fluid. The arthritis was shown to persist even though the initial inciting agent could not be isolated from the advanced cases of chronic polyarthritis. This strongly suggests that the pathological process responsible for this arthritis can become autonomic and probably is related to a state of hypersensitivity. The cellular changes observed in the synovial fluid did not differ markedly from those of rheumatoid arthritis in man. Synovial fluid mucinous changes were apparent in the decreased viscosity observed grossly. Definite changes in the character of the precipitate produced by acetic acid treatment of the fluid were also observed. PMID- 4221914 TI - [Survey of a sample of subjects with altered working capacity]. PMID- 4221913 TI - Observations on a swine herd health program. AB - Observations on a swine herd health program are reported. A primary purpose was to show that such programs could provide economic benefits to swine breeders and sources for breeding stock of minimum disease status. The possible influence of diseases of swine, including atrophic rhinitis and virus pneumonia, on both aspects are discussed. The inadequacy of knowledge of diseases of swine, both specifically and generally, is pointed out. Veterinary supervision of a swine herd will result in economic benefits to an average capable owner. There is both merit and need for such programs, but as to what health standards would be reasonable, practical, and meaningful, is still not clearly defined. PMID- 4221915 TI - [Lumbar hyperlordosis, coupled with lower backache. Several aspects of physical management]. PMID- 4221916 TI - [Naphthalene oxidizing bacteria in ground waters of oil beds]. PMID- 4221917 TI - [Bacterial plankton and bacterial periphyton in various biotopes of Siamozero]. PMID- 4221918 TI - [Amino acid biosynthesis by actinomycetes isolated from the soil of Pamir]. PMID- 4221919 TI - Abnormal bleeding conditions in urologic patients. PMID- 4221920 TI - Gas gangrene infection: combined treatment including 3,432,000 international units of polyvalent gas gangrene antitoxin. PMID- 4221922 TI - Carcinoma of the tongue: the role of chronic irritation. PMID- 4221921 TI - Brachial artery puncture: an oft neglected clinical tool in the evaluation of hypertension. PMID- 4221923 TI - [Incisions in obese patients, particularly in gynecological operations]. PMID- 4221924 TI - Studies on reticuloendothelial system and hemaotpoiesis. I. Studies of extramedullary hematopoiesis. PMID- 4221925 TI - The appearance of perinucleolar halos in cultured cells with 5-fluorouracil. PMID- 4221926 TI - Neotetrazolium salt (NT) as an electron acceptor in living cell: a study on the JTC-3 and HeLa cells in culture. PMID- 4221927 TI - A histochemical study on the structural differences of motor endplate in the red, white and intermediate muscle fibers of mouse limb muscle. PMID- 4221928 TI - On the relationship of vascular wall and connective tissue. Histological, immunological and radiochemical investigations. PMID- 4221929 TI - Heart weight of Jamaicans. Autopsy study of normal cases and cases of hypertension and chronic lung disease. PMID- 4221931 TI - [The EKG diagnosis of cardiac hypertrophies]. PMID- 4221930 TI - Analysis of experience in workmen's compensation for heart cases. Factors influencing the decision re compensability in heart attacks occurring among industrial workers. PMID- 4221933 TI - [Clinical reactions in children after the administration of the Leningrad-4 live measles vaccine according to data from Kirghizia]. PMID- 4221932 TI - You take him as you find him. PMID- 4221934 TI - [Studies on the epidemiological effectiveness in Kirghizia of a live measles vaccine prepared from the Leningrad-4 strain]. PMID- 4221935 TI - [Results of the use of the live measles vaccine of the Leningrad Pasteur Institute of Epidemiology and Microbiology in Alma-Ata]. PMID- 4221937 TI - A comprehensive care program for children with handicaps. PMID- 4221936 TI - Severe mucocutaneous and systemic reactions to drugs occurring in five patients during treatment for pulmonary tuberculosis. PMID- 4221938 TI - The "D" syndrome. Report of four trisomic and one D/D translocation case. PMID- 4221939 TI - Morphological Philadelphia chromosome. Occurrence in a child with congenital anomalies. PMID- 4221941 TI - Formal discussion: future prospects in leukemia chemotherapy. PMID- 4221942 TI - [Some hemodynamics aspects and blood indices in patients with circulatory disorders in Pamir Mountains]. PMID- 4221943 TI - Phytohaemagglutinin on maternal and umbilical leukocytes. PMID- 4221940 TI - Hepatic ultrastructure in the Hurler syndrome. PMID- 4221944 TI - Cellular antibody in mice bearing Ehrlich cancer. II. Properties of lymphoid cells from sensitized animal. PMID- 4221945 TI - [Occupational dermatoses with mycotic microbial allergy. Trials of desensitization]. PMID- 4221946 TI - Connotative reactions of college students to disability labels. PMID- 4221947 TI - Tuning forks. A diagnostic aid in hearing loss. PMID- 4221948 TI - The control system governing bone growth in response to mechanical stress. PMID- 4221949 TI - A history of the therapy of angina pectoris. PMID- 4221950 TI - Battered child syndrome. PMID- 4221951 TI - Carcinoma of the cervix in young women. PMID- 4221952 TI - Obstruction of the superior vena cava. PMID- 4221953 TI - Dissociation of a complex of F-actin and H-meromyosin by addition of adenosine triphosphate. PMID- 4221954 TI - Histochemical studies on the adrenal medullary cells of the marmoset (Callithrix jacchus). PMID- 4221955 TI - Suggestions for a histochemical terminology of carbohydrate-rich tissue components. PMID- 4221956 TI - Biophysical and biochemical studies of healing fractures, with special reference to glycoaminoglycans. PMID- 4221957 TI - [Current therapy of chronic lupus erythematosus]. PMID- 4221959 TI - [Treatment of rhinophyma]. PMID- 4221958 TI - [Occupational skin diseases in the fur industry]. PMID- 4221960 TI - Religion and physical disability. PMID- 4221961 TI - Cardiovascular abnormalities in infants malnourished before birth. PMID- 4221962 TI - Dental and facial characteristics in Down's syndrome. (Mongolism). PMID- 4221963 TI - [Histoenzymatic studies on the behavior of succinic acid dehydrogenase, NADH-2 tetrazolium reductase, adenosine triphosphatase and alkaline phosphatase in cases of uterine cervix cancer]. PMID- 4221964 TI - Management of crushed chest injuries. PMID- 4221965 TI - The radioisotope blood pool scan. PMID- 4221966 TI - Evaluation of rehabilitation in home or clinic setting: problems in methodology. PMID- 4221967 TI - [A problem of temporary incapacity]. PMID- 4221969 TI - The yaws elimination campaign in Malaya. PMID- 4221968 TI - [Microbiological transformation of dehydroepiandrosterone, progesterone, desoxycorticosterone, and testosterone by Gibberella saubinetti]. PMID- 4221970 TI - University education and personality problems of undergraduates. PMID- 4221971 TI - The rehabilitation of severely disabled boys. PMID- 4221972 TI - A report of the incidence of positive tuberculosis skin test reactors and the incidence of active Tuberculosis among school children in the Methodist schools, Kapit district, Sarawak, Malaysia. PMID- 4221973 TI - Investigation of ophthalmological conditions in Kelantan. PMID- 4221974 TI - A comparative epidemiologic study of fractures among Indian, Malay and Swedish children. PMID- 4221975 TI - A rapid method for the identification of Candida albicans by the use of a serum- glucose preparation. PMID- 4221976 TI - Uric acid diathesis as met with in Kuala Kangsar district hospital. PMID- 4221977 TI - Human and veterinary medicine. PMID- 4221978 TI - The role of the pharmacist in the community. PMID- 4221979 TI - [Mucopolysaccharides and glycocorticoids in infants with weight deficit]. PMID- 4221980 TI - [Effects of inhibitors of desoxyribonucleic acid in the multiplication of bacteriophage phi-x-174]. PMID- 4221981 TI - [Dissociation of the processes of synthesis of macromolecules in the bacteriophage phi-x-174--E. coli C. system]. PMID- 4221982 TI - [Niacin, N-1-methylnicotinamide and riboflavin excretion of young women fed different amounts of niacin and riboflavin in the diet]. PMID- 4221983 TI - MEND, a rehabilitation program. PMID- 4221984 TI - An occupational therapist's role in oral hygiene for the handicapped. PMID- 4221985 TI - An energy-dependent hydrogen-evolution from dithionite in nitrogen-fixing extracts of Clostridium pasteurianum. PMID- 4221986 TI - Effects of parathyroid hormone and other proteins in vitro on mitochondrial metabolism. PMID- 4221987 TI - Symptoms and pathology produced by toxic Microcystis aeruginosa NRC-1 in laboratory and domestic animals. AB - Toxicity tests with lyophilized M. aeruginosa NRC-1 cells have been conducted using mice, guinea pigs, rabbits, chickens, ducks, two calves and one lamb as the test animals. The symptoms and pathological changes are described. On an equivalent weight basis it required three to five times the oral dosage to kill the large animals and birds as it did to kill the laboratory animals. The symptoms were less pronounced and the survival times were longer in the more resistant animals. Enlargement and congestion of the liver with necrosis of the hepatic cells were constant and pathognomonic. These findings are in general agreement with the observations of other workers who have examined the toxicity of naturally occurring Microcystis waterblooms. The toxicities and structures of microcystin and of six other biologically active cyclic polypeptides are summarized. The pathological effects produced by microcystin in laboratory and domestic animals resemble those produced in man but differ from those produced in animals by the toxic peptides of Amanita phalloides. PMID- 4221988 TI - Preliminary bluetongue Transmission with the sheep ked Melophagus ovinus (L.). AB - Five experiments indicated that the sheep ked MELOPHAGUS OVINUS (L.), can transmit bluetongue virus (BTV) in sheep. It was not determined whether these were mechanical or biological transmissions, although the results suggested mechanical transmission. Sheep keds were manually transferred from a BTV-host sheep to 18 susceptible test sheep. Of these, 10 were positive (5 with mild reactions), 6 questionable, and 2 negative for BTV. Three of the mildly reacting sheep and 3 of the questionable sheep had highly intensified reactions on challenge inoculation. Five of the positive sheep were immune on challenge inoculation. Blood from 2 positive reactors was subpassaged into susceptible sheep, which reacted with typical disease signs. PMID- 4221989 TI - Epithelial inclusions of a bovine heart. PMID- 4221990 TI - Hog cholera IV. Detection of the virus in tissue culture preparations by the fluorescent antibody technique. AB - The fluorescent-antibody technique was employed for detection of hog cholera virus in tissue cultures inoculated with spleens of infected animals. As controls, cultures were also inoculated with material from normal swine and from those infected with other agents. In the first series 71 of 73 infected spleens, or 97 per cent, were detected. There were no false positive reactions among the controls. Results obtained with the second series of pigs showed that spleens collected during advanced stages of the disease were more satisfactory specimens than those collected earlier during the high temperature phase of infection. Findings with the third series of older swine indicated that their spleens were less satisfactory as a source of virus than those from young pigs. Tissues from freshly killed animals provided better specimen material than those from animals which had died. PMID- 4221991 TI - Microbiological transformations of terpenes. VI. Studies on the mechanism of some fungal hydroxylation reactions with the aid of model systems. PMID- 4221993 TI - Bacterial metabolism of hydroxyproline. II. Metabolism of L-hydroxyproline in Achromobacter. PMID- 4221992 TI - Bacterial metabolism of hydroxyproline. I. Metabolism of L-allohydroxyproline by a Pseudomonas. PMID- 4221994 TI - Distribution of alpha-glucosidase activities in human & monkey small intestine. PMID- 4221995 TI - Synthesis of serum proteins in carbon tetrachloride injured rat & effect of vitamin B12 protection. PMID- 4221996 TI - Incorporation of orotic acid-14C in a logarithmically growing culture of Escherichia coli. PMID- 4221997 TI - A critical study of the conditions for colorimetric estimation of serum transaminases. I. Estimation of small amounts of pyruvic acid in the presence of ketoglutarate using dinitrophenylhydrazine. PMID- 4221998 TI - Changes in the composition of striated muscle proteins of rat at different stages after birth. PMID- 4221999 TI - Studies on hepatic glycogenolysis in protein malnutrition. PMID- 4222001 TI - Studies on the proteose-peptone fraction of milk: isolation & properties of proteose-peptone & proteose from cow & buffalo milk. PMID- 4222000 TI - A comparative study on the release of peptides from buffalo & cow milk caseins by trypsin. PMID- 4222002 TI - Haemagglutinins of field bean (Dolichos lablab). I. Isolation, purification & properties of haemagglutinins. PMID- 4222003 TI - Haemagglutinins of field bean (Dolichos lablab). II. Effect of feeding field bean haemagglutinin A on rat growth. PMID- 4222004 TI - Finger print patterns of peptic and alpha-chymotryptic digests of ox liver and erythrocyte catalases. PMID- 4222005 TI - Essential amino acid requirements of the silkworm, Bombyx mori L. PMID- 4222007 TI - Record of the guinea worm-Dracunculus medinensis in an Alsatian bitch. PMID- 4222006 TI - Lactic acid & lactic dehydrogenase activity in the blood of patients with essential hypertension. PMID- 4222008 TI - [Studies of hemoglobin types in the population of Lebanon]. PMID- 4222009 TI - Effect of plasmin on outflow resistance in the primate eye. PMID- 4222010 TI - [Inactivation of Brucella phages by antigen substrates of Brucella. I]. PMID- 4222011 TI - [Inhibition of the activity of brucella phages by means of chemical fractions of Br.melitensis]. PMID- 4222012 TI - [Studies on staphylococcal hyaluronidase. VI. Research on the relation between the ability to form hyaluronidase and other microbiological properties of Staph. aureus]. PMID- 4222013 TI - [Ocular manifestations of leukosis]. PMID- 4222015 TI - [Bourneville's tuberous sclerosis]. PMID- 4222014 TI - [Apropos of 55 cases of Lowe's syndrome]. PMID- 4222016 TI - [Malherb's tumor (so-called calcified epithelioma) in orbito-palpebral location]. PMID- 4222017 TI - [Solitary neuroma of the orbit]. PMID- 4222018 TI - [The sub-epithelial acellular fibrillar zone of the cornea of the embryo. Its relation to the formation of the epithelial basal membrane and Bowman's membrane]. PMID- 4222019 TI - [Audiologic findings in mongoloid subjects]. PMID- 4222020 TI - Marquio's disease. PMID- 4222021 TI - The evaluation of verbal performance in multiply handicapped blind children. PMID- 4222022 TI - [Some sober remarks on the treatment of acne]. PMID- 4222023 TI - The primary histologic lesion of seborrheic dermatitis and psoriasis. PMID- 4222025 TI - [Biology of the sclerosis process. 23. Histochemistry of the mucopolysaccharides of the endothelial and fibroblastic zones of the intima of the human aorta and coronary arteries]. PMID- 4222024 TI - Occupational disease. PMID- 4222026 TI - Right ventricular hypertrophy at high altitude. PMID- 4222028 TI - Hexosamine and acid glycosaminoglycans in human teeth. PMID- 4222027 TI - Incorporation of D-[I-14C]galactosamine into serum proteins and tissues of the rat. PMID- 4222029 TI - Acid mucopolysaccharides of tadpole tail fin and back skin. PMID- 4222030 TI - Acid mucopolysaccharide composition of human-heart valve. PMID- 4222031 TI - Isolation of neutral sugar-containing mucopolysaccharides from cattle retina. PMID- 4222032 TI - The effect of sulfate deficiency on the mechanical strength of the rat's aorta. PMID- 4222033 TI - The isolation of a dermatan sulphate-protein complex from bovine heart valves. PMID- 4222034 TI - The interaction of collagen and acid mucopolysaccharides. A model for connective tissue. AB - 1. The interaction of acid mucopolysaccharides of connective tissue with solubilized collagen of native, or near-native, structure was investigated by free solution electrophoresis at pH7.0. 2. Complex-formation was detected by the appearance of a third peak in the ascending limb only, indicating reversible association. 3. Complex-formation was destroyed by prior heating of solubilized collagen, indicating a probable requirement for high molecular weight or internal structure of the protein. 4. Hyaluronate and chondroitin sulphate of mol.wt. 50000 gave complexes with soluble collagen at I 0.4, whereas heparin and chondroitin sulphate of mol.wt. 15000-18000 did not. All mucopolysaccharides yielded complexes at I 0.1. The stability of the complex appears mainly dependent on electrostatic forces and is increased with increase in chain length of the polysaccharide. 5. Solubilized collagen interacted to yield gels with the ;native' chondroitin sulphate-protein macro-molecule from cartilage. 6. A schematic model for the interaction of collagen and chondroitin sulphate-protein macromolecules shows parallel-ordered interaction of collagen fibrils with chondroitin sulphate side chains of the chondroitin sulphate-protein macromolecule. The biological implications of this model are discussed, particularly in relation to the ordered structures and the ionic-network properties of the intercellular components of connective tissue. PMID- 4222035 TI - The activation of mitochondrial adenosine triphosphatase by calcium. PMID- 4222036 TI - An adenosine triphosphatase from frog gastric mucosa. PMID- 4222037 TI - [On the problem of military service and multiple sclerosis with reference to the new drafting of the Federal Service Act of 21 February 1964]. PMID- 4222038 TI - [Results, case records and discussions. Provisions of Paragraph 89, 2d Federal Service Act, particularly Paragraph 1, Item 3, 2d Federal Service Act]. PMID- 4222039 TI - [Distribution of ATP-ase activity in the guinea pig cochlea. Histochemical investigation]. PMID- 4222040 TI - Histologic changes produced by endotracheal intubation. PMID- 4222041 TI - [Acne conglobata]. PMID- 4222042 TI - [Histoenzymologic modifications within the white substance and at the level of the vascular walls during the maturation of the rat brain]. PMID- 4222043 TI - The accumulation of sodium and calcium in a specific layer of frog skin. PMID- 4222044 TI - The painful shoulder. The scapulocostal syndrome in shoulder pain. PMID- 4222045 TI - [Investigations on the influence of chloroquine on the neuromuscular conduction and on the striated muscle]. PMID- 4222046 TI - Structure of a polysaccharide protein complex. PMID- 4222047 TI - [Apropos of the compensation for certain industrial bronchopneumopathies]. PMID- 4222049 TI - [Static disorders during sedentary work, in particular in shorthand-typists]. PMID- 4222048 TI - [The particular situation of physically handicapped women]. PMID- 4222051 TI - A study on dermatitis in rice farmers. PMID- 4222050 TI - Variations in lipid intake and their influence on respiration and tricarboxylic acid cycle activity. PMID- 4222053 TI - [A new instrument for biopsy of the peritoneum during laparoscopy]. PMID- 4222052 TI - Meiosis in a male with Down's syndrome. PMID- 4222054 TI - A new deal for the aged and disabled. PMID- 4222056 TI - Heart attacks and workmen's compensation acts. PMID- 4222055 TI - Cardiomegaly after repeated application of isoprenalin in the rat. PMID- 4222057 TI - The social distance of the exceptional: a study at the high school level. PMID- 4222058 TI - Model train helps the limbless. PMID- 4222059 TI - [Rehabilitation]. PMID- 4222060 TI - [Reactogenic properties of the Leningrad-4 measles vaccine according to data from Moldavia]. PMID- 4222061 TI - [Reactivity and epidemiological effectiveness of the measles vaccine of the Leningrad Pasteur Institute of Epidemiology and Microbiology in Baku]. PMID- 4222062 TI - The role of phosphofructokinase in metabolic regulation. PMID- 4222063 TI - Effect of changes in hormonal and dietary status of rats and mice on the activity of their liver glutamic dehydrogenases. PMID- 4222064 TI - [Therapy of non-specific intestinal disorders in patients with pulmonary tuberculosis with Mexaform S]. PMID- 4222065 TI - The abdominal neourethra. PMID- 4222066 TI - [On combined therapy of lumbar pain in women with ultrasonics and medical gymnastics-massage]. PMID- 4222067 TI - [Progressive effect of its entrance into the Russian community on the development of medico-sanitary activity in Azerbaijan]. PMID- 4222068 TI - [A contribution to the clinical picture of congenital defects of the abdominal muscles and related anomalies of urogenital and intestinal systems]. PMID- 4222070 TI - [Vitamin A deficiency in piglets with seborrheic eczema]. PMID- 4222069 TI - Toxic epidermal necrolysis (the scalded skin syndrome). Its association in two cases with pathogenic staphylococci and its similarity in infancy to Ritter's disease. PMID- 4222071 TI - A symmetrical simultaneous paried comparison of triamcinolone acetonide ointment and cream. PMID- 4222072 TI - Electromyographic validation of pain relief: a pilot study in orthopedic patients. PMID- 4222073 TI - Investigations on a plasminogen activator in two blood-suckers, Rhodnius prolixus Stal and Hirudo medicinalis. PMID- 4222074 TI - Studies on acid mucopolysaccharides of pig gastric mucin. II. PMID- 4222075 TI - Modification of breakage and reunion in relation to lethal damage. PMID- 4222076 TI - [Physiology and physiopathology of mucopolysaccharides]. PMID- 4222077 TI - [On the binding of acridine orange by muscle proteins]. PMID- 4222078 TI - A family study of Huntington's chorea with unusual manifestations. PMID- 4222079 TI - State or Federal Workmen's Compensation--a conflict. PMID- 4222080 TI - Progress in workmen's compensation. PMID- 4222081 TI - Progress in rehabilitation of the injured worker. PMID- 4222082 TI - Dehydroepiandrosterone in human seminal plasma. PMID- 4222083 TI - The coronary spectrum. Essentials of the legal issues in workmen's compensation. PMID- 4222084 TI - Psychiatry and the rehabilitation of the physically disabled. PMID- 4222085 TI - [So-called fibroplastic myocarditis in oxalosis]. PMID- 4222086 TI - Diagnosis of Hurler's syndrome in the hospital laboratory and the determination of its genetic type. PMID- 4222087 TI - Indication for an allosteric effect of ADP on actomyosin gels and glycerinated fibres from insect fibrillar flight muscle. PMID- 4222088 TI - Clinical experiences in ureteroileocutaneostomy. PMID- 4222089 TI - Modern cytogenetic technics. Clinical review of chromosomal analyses in a children's hospital. PMID- 4222090 TI - [Problems of temporary incapacitation]. PMID- 4222091 TI - The direction of animal care. PMID- 4222092 TI - Spontaneous tumors in the Mongolian gerbil. PMID- 4222093 TI - A comparison of the growth and fat utilization of Caesarean-derived and conventional albino rats. PMID- 4222094 TI - Paraldehyde: an anesthesia for recovery experiments in albino rabbits. PMID- 4222095 TI - Pasteurella pneumotropica: cultural and biochemical characteristics, and its association with disease in laboratory animals. PMID- 4222096 TI - Normal values for hemoglobin concentration and cellular elements in the blood of Mongolian gerbils. PMID- 4222097 TI - The sterilisation of laboratory animal diet by ethylene oxide. PMID- 4222098 TI - The care, handling and anesthesia of the snowshoe hare (Lepus americanus). PMID- 4222099 TI - The metabolism, pulse rate and body temperature of normal, thyroidectomized and hypermetabolic rats. PMID- 4222100 TI - Semi-automatic recording and electronic processing of chronic rat toxicity data. PMID- 4222102 TI - A comparison of the hemograms of conditioned and non-conditioned laboratory dogs. PMID- 4222101 TI - A study of the efficacy of thiabendazole and dithiazanine iodide-piperazine citrate suspension against intestinal parasites in the Macaca mulatta. PMID- 4222104 TI - A foot-operated watering device for use with special fluids. PMID- 4222103 TI - Environmental factors influencing stereotyped and allelomimetic behavior in animals. PMID- 4222105 TI - The faultless mouse holder. PMID- 4222106 TI - A technique for prolonged infusion of rats. PMID- 4222107 TI - The mansion on Richmond Hill. PMID- 4222109 TI - Neuro-muscular transmission in the kitten. A preliminary note. PMID- 4222108 TI - Symposium: The handicapped child. PMID- 4222110 TI - Potassium transport and control of glycolysis in human erythrocytes. PMID- 4222112 TI - Studies of enzyme systems utilizing automated methodology. PMID- 4222113 TI - Burn wound complication. PMID- 4222111 TI - Effects of vitamin A on mucopolysaccharides of rat blood platelets. PMID- 4222115 TI - Twins, probably monozygotic: one mongoloid with 48 chromosomes, the other normal. PMID- 4222114 TI - The relation of the light-dependent and light-triggered adenosine triphosphatases to photophosphorylation. PMID- 4222116 TI - [Remarks on cases of cement eczema observed in the dermato-venerological clinic of Lausanne from 1947 to 1961]. PMID- 4222117 TI - An effective oral antifungal for chronic infections in the aged. PMID- 4222118 TI - Onychomycosis treated with ultrafine griseofulvin. PMID- 4222119 TI - [Identification and chromatographic separation of organo-phosphoric acids by means of their methyl esters]. PMID- 4222120 TI - Care and raising of newborn baboons. PMID- 4222122 TI - The trematodes of laboratory primates. PMID- 4222121 TI - The need for a large standard laboratory dog. PMID- 4222123 TI - A method for intravenous injection and collection of blood from rats and mice without restraint and anesthesia. PMID- 4222124 TI - The hematogram of the squirrel monkey (Saimiri sciureus). PMID- 4222125 TI - The germfree cat. PMID- 4222126 TI - Successful prevention of infantile diarrhea of mice during an epizootic by means of a new filter cage unopened from birth to weaning. PMID- 4222127 TI - A device to restrain the mouse, rat, hamster and chinchilla to facilitate semen collection and other reproductive studies. PMID- 4222128 TI - Small laboratory animal feeding technique. PMID- 4222129 TI - A rat resuscitator. PMID- 4222130 TI - Infertility of guinea pigs on sawdust bedding. PMID- 4222131 TI - [Data on the simultaneous occurrence of hemoblastic leukemia and Down's disease]. PMID- 4222132 TI - [Eczema caused by allergy to nickel]. PMID- 4222133 TI - [Embryonic development of neuromuscular spindles in the musculature of the forearm in man]. PMID- 4222134 TI - [Some epidemiological and administrative aspects of control of venereal diseases]. PMID- 4222135 TI - [Health and industrial development in Latin America]. PMID- 4222136 TI - [The financing of drinking-water supply programs]. PMID- 4222137 TI - [The work of the Inter-American Development Bank in the field of water supply and sewage disposal in Latin America]. PMID- 4222138 TI - [Methods of salt iodization]. PMID- 4222139 TI - [Epidemiology of hydatidosis in Peru]. PMID- 4222140 TI - [Importance and epidemiological characteristics of venereal diseases]. PMID- 4222141 TI - [The role of the epidemiologist in the planning of economic development]. PMID- 4222142 TI - [Training of personnel for water supply programs]. PMID- 4222143 TI - [Problems of sanitary engineering education]. PMID- 4222144 TI - [Resources for water supply investigations]. PMID- 4222145 TI - [Effect of salt iodization on the prevalence of endemic goiter in school children in Guatemala]. PMID- 4222146 TI - [Case finding in venereal disease control]. PMID- 4222147 TI - [Community participation in malaria eradication]. PMID- 4222148 TI - Enzyme-histochemical studies on the healing process of split skin grafts. II. 5 Nucleotidase, adenosinetriphosphatase, acid and alkaline phosphatase in autografts. PMID- 4222149 TI - [Investigations on the effect of thyroid function on collagen metabolism]. PMID- 4222150 TI - [Relationships between iron concentration and resorption in the isolated small intestine of normal and anemic rats]. PMID- 4222151 TI - [On cyanocobalamine substitution by thiamine and the catalytic influence of nicotinic acid amide on this reaction. 9. Galenics of vitamins]. PMID- 4222152 TI - [Changes in reaction time and the electroencephalogram under the influence of vitamin PP]. PMID- 4222153 TI - Nicotinamide content of insects. PMID- 4222154 TI - Studies with the ATPase of adrenal medulla. PMID- 4222155 TI - Lysogenic conversion of staphylococci to loss of beta-toxin. PMID- 4222156 TI - The autolysis of Clostridium sporogenes. PMID- 4222157 TI - Heart size after isolated replacement of mitral or aortic valve. PMID- 4222158 TI - [Recent studies on the treatment of endocardial fibrosis]. PMID- 4222159 TI - [Urinary excretion of 5-hydroxyindoleacetic acid, vanillomandelic acid and xanthurenic acid in 18 Mongoloids]. PMID- 4222160 TI - [Dynamics of some biochemical indices in clinical cerebral rheumatism]. PMID- 4222161 TI - [On the technic of variating and derotating intertrochanteric femoral osteotomy with a sliding groove fixation in dislocated hips in children]. PMID- 4222162 TI - [The dorso-ventral close-up of the upper ankle joint]. PMID- 4222163 TI - [Use of the "Nevsky-12" non-agglutinogenic strain vaccine against brucellosis]. PMID- 4222164 TI - [The eradication of bovine brucellosis in the regions, terratories and autonomous republics of the Russian Federation]. PMID- 4222165 TI - Eradication of bovine brucellosis in Moscow region. PMID- 4222166 TI - Some questions of diagnosis of brucellosis and specific preventive measures in the Kazakh Soviet Republic. PMID- 4222167 TI - Arthus-like reaction of skin allograft (homograft) induced by serum antibodies. PMID- 4222168 TI - [Psychiatric aspects of mongolism]. PMID- 4222169 TI - [Experiences in the treatment of acne vulgaris with Loticort]. PMID- 4222171 TI - Panel on medicolegal considerations in workmen's compensation. PMID- 4222170 TI - [Role of the psychoprophylaxis and psychotherapy in the rehabilitation of crippled children]. PMID- 4222172 TI - [Method for the application of fistulae to some organs of the abdominal cavity using combined tubes]. PMID- 4222173 TI - [N-cholinolytic activity and pi-electronic structure of the molecule]. PMID- 4222174 TI - Disorders of the hair and their treatment before the 18th century. PMID- 4222175 TI - The influence of rotation of the trunk on the anatomy of the inguinal canal. PMID- 4222176 TI - The pesticide problem--return to sanity. PMID- 4222178 TI - Enzyme nomenclature. Recommendations of the International Union of Biochemistry. PMID- 4222177 TI - Technical errors in peritoneoscopy. PMID- 4222179 TI - Nicotinamide deamidase from rabbit liver. PMID- 4222180 TI - [Desmoid tumor of the abdominal wall in a child]. PMID- 4222181 TI - Extracellular space in the central nervous system. PMID- 4222182 TI - The influence of parathyroid extract on phalanges of the embryonic fowl in vitro. PMID- 4222183 TI - The occurrence of some carbohydrates and collagen in Obeliscoides cuniculi (Graybill, 1923), a nematode parasite of the rabbit. PMID- 4222184 TI - Congenital defects involving the abdominal wall, sternum, diaphragm and pericardium: case report and review of embryologic factors. PMID- 4222185 TI - [Orbital mucormycosis. Anatomo-clinical study and review of the literature]. PMID- 4222186 TI - [Primary multiple tumors of ophthalmological localization]. PMID- 4222187 TI - [Is it possible to improve the results of cataract extraction in diabetics?]. PMID- 4222188 TI - [Histoarchitectony of the ciliary muscle and a theory on myociliary dynamics]. PMID- 4222189 TI - [Ultrastructure of the sutural fibers of the cornea of Elasmobranch fishes]. PMID- 4222190 TI - [The treatment of ptosis by the "palpebral spring"]. PMID- 4222191 TI - Early loss of teeth in children. PMID- 4222192 TI - Acrodynia or pink disease. PMID- 4222193 TI - Massive melena. PMID- 4222194 TI - Diagnosis and treatment of parathion poisoning. PMID- 4222195 TI - Molecular events resulting in radiation injury, repair and sensitization of DNA. PMID- 4222197 TI - Appendicitis in pregnancy. PMID- 4222196 TI - Annual report: Arkansas State Board of Health. PMID- 4222198 TI - The compromised fetus. PMID- 4222199 TI - Arkansas morbidity--1965. PMID- 4222200 TI - The nursing situation. PMID- 4222201 TI - Application of psychological principles to dental practice. PMID- 4222202 TI - Premedication for children. PMID- 4222203 TI - The impact of water fluoridation on the practice of dentistry for children. PMID- 4222204 TI - The effect of appointment length on behavior of the pedodontic patient and his attitude toward dentistry. PMID- 4222205 TI - [On local therapy of inflammatory skin diseases with Locacorten]. PMID- 4222206 TI - The psychological preparation of the child for dental surgery. II. PMID- 4222207 TI - Activity projects. PMID- 4222208 TI - Preparatory training bureau. PMID- 4222209 TI - Banstead Place. PMID- 4222210 TI - [Take your child to the dentist]. PMID- 4222211 TI - Measurement of anxiety in children during routine dental procedures. PMID- 4222212 TI - What do Georgia dentists think about dentistry for mentally retarded children? PMID- 4222213 TI - Dental care for children. PMID- 4222214 TI - Dental problems and programs for the chronically ill and aging. PMID- 4222216 TI - Dentistry's new horizon--dentistry for the handicapped. PMID- 4222215 TI - The effectiveness of the electric toothbrush in reducing oral debris in handicapped children. PMID- 4222217 TI - Independence in a wheelchair; useful booklet for the disabled. PMID- 4222218 TI - Industrial dermatitis. PMID- 4222219 TI - Industrial dermatitis. PMID- 4222220 TI - The long struggle against crippling disease. PMID- 4222221 TI - [Insure the children and reform the public dental health]. PMID- 4222223 TI - Dental care for retarded children. PMID- 4222222 TI - [Occupation for the disabled and aged at home]. PMID- 4222224 TI - John Groom's crippleage. PMID- 4222226 TI - The composition of the cell wall of Lactobacillius bifidus var. pennsylvanicus. PMID- 4222227 TI - [Studies on the control of penicillin resistance of Staphylococcus aureus haem. By phenanthroline quinone, iodochlorhydroxyguinoline and Mexaform]. PMID- 4222228 TI - The effect of quinidine on the activity of a sodium-potassium activated, magnesium-dependent ATPase enzyme isolated from toad cardiac muscle. PMID- 4222229 TI - A cation activated adenosinetriphosphatase in cell membranes of halophilic Vibrio parahaemolyticus. PMID- 4222230 TI - The effect of carnosine on myofibrillar ATPase activity. PMID- 4222231 TI - Depression of facilitatory influences on spinal motor activity by carisoprodol. PMID- 4222232 TI - Staphylococci in man and animals. Distribution and characteristics of strains. PMID- 4222233 TI - [Similarity of effects (static or dynamic) exercised by single fusimotor fibers on the primary endings of several spindles in the cat]. PMID- 4222234 TI - Experiences with peritoneoscopy at Walter Reed General Hospital, 1964-1965. PMID- 4222235 TI - Diagnostic considerations in management of penetrating abdominal wounds. PMID- 4222236 TI - The management of gunshot wounds of the extremities. PMID- 4222237 TI - Neurologic phenomena of leukemia. PMID- 4222238 TI - Urinary output of total and individual fractions of 17-ketosteroids in patients with acne. PMID- 4222239 TI - Massive left atriomegaly. PMID- 4222240 TI - Thyrocardiac disease--fact or fancy? PMID- 4222241 TI - Contact dermatitis caused by the 'manzanillo' (Rhus striata) tree. Report of three cases. PMID- 4222242 TI - Rupture of the inferior epigastric artery with rectus-sheath hematoma. PMID- 4222243 TI - Limitations of the electrocardiographic diagnosis of ventricular hypertrophy. PMID- 4222244 TI - [Quantitative studies on the Arthus reaction in rats]. PMID- 4222245 TI - [Microbiological characteristics of some ore deposits in Central Kazakhstan]. PMID- 4222246 TI - The failure of some aromatic amines to produce hemiglobin in vivo in spite of microsomal N-hydroxylation. PMID- 4222247 TI - The low activity of aniline in producing hemiglobin in rabbits. PMID- 4222248 TI - The formation of hemiglobin by p-hydroxylaminobenzenesulfonamide in vivo and in vitro. PMID- 4222249 TI - [Animal experimental studies on the treatment of acute iron poisoning]. PMID- 4222250 TI - [Therapy of some forms of acne with a new preparation: Neo Medrol acne lotion]. PMID- 4222251 TI - [Data on comparative epidemiology of schizophrenia in cities and rural locations]. PMID- 4222252 TI - [Effects of enovid on female acneic dermatosis: experimental study with sebo test]. PMID- 4222253 TI - How a pharmaceutical manufacturer tests products for sterility. PMID- 4222254 TI - Clean room garment selection and care. PMID- 4222256 TI - Emerging problems in oral health care and clinical research in a chronic disease hospital. PMID- 4222257 TI - Regulation of metabolism in working muscle in vivo. II. Concentrations of adenine nucleotides, arginine phosphate, and inorganic phosphate in insect flight muscle during flight. PMID- 4222258 TI - Studies on thymidine kinase of human liver cells in culture. PMID- 4222259 TI - [Morphology of experimental chloroquine retinopathy in the rabbit]. PMID- 4222261 TI - Special schools over a century. PMID- 4222262 TI - Wheel-chairs on the campus? PMID- 4222263 TI - [Factors of the fibrinolytic system in liver diseases]. PMID- 4222265 TI - [Electrocardiographic aspects of arterial hypertension]. PMID- 4222266 TI - [Recovery of yellow fever virus from a sentinel monkey in the vicinity of Belem, Brazil]. PMID- 4222267 TI - [Importance of case detection in venereal disease control]. PMID- 4222268 TI - Cerebral biopsy in the investigation of presenile dementia. I. Clinical aspects. PMID- 4222269 TI - [On intermittent griseofulvin treatment of onychomycoses]. PMID- 4222270 TI - Salutary effects of prochlorperazine on chronic psychotic choreo-athetosis. PMID- 4222272 TI - [Prevention and rehabilitation in acne vulgaris]. PMID- 4222273 TI - [Electron microscopic investigation on mesenchymal tissues and their different modes of reaction]. PMID- 4222274 TI - [Diagnostic significance of transaminase activity in traumatology]. PMID- 4222275 TI - Role of phospholipid in the activation of Na+, Ka+-activated adenosine triphosphatase of beef brain. PMID- 4222277 TI - Cellular response of seborrheic keratosis following croton oil irritation and surgical trauma with special reference to melanoacanthoma. PMID- 4222279 TI - [Diagnostic value of lumbosacral roentgenologic examination. (On the problem of indication for lumbosacral roentgenologic examination based on 5195 cases)]. PMID- 4222278 TI - Comparative studies on serum lipids and histochemical features of the arterial wall in animal species differently susceptible to experimental atherosclerosis. PMID- 4222280 TI - [Dermatological indications for reuse of Aristolochia acid]. PMID- 4222281 TI - Visual discrimination learning in imbecile children with nonreinforcement of irrelevant tendencies. PMID- 4222282 TI - The nucleoli in mitotic divisions of mammalian cells in vitro. AB - In a number of mammalian cell strains nucleoli persisted through mitosis. This phenomenon was especially pronounced in several cell lines derived from Chinese hamster tissues. All the methods employed, including radioautography with tritiated uridine, cytochemical stains (methyl green-pyronin and azure B), fluorescent microscopy (coriphosphine O), ribonuclease digestion, and electron microscopy, demonstrated that the bodies identified as persistent nucleoli in the mitotic stages had the same characteristics as did the nucleoli in the interphase. Persistent nucleoli may attach to the chromosomes or may be free in the cytoplasm. In cells where no persistent nucleoli as such were noted, nucleolar material was observed to attach to the chromosomes in shapeless masses which moved with the chromosomes during anaphase. At least a portion of the nucleolar material was included in the daughter nuclei, presumably for immediate use for protein synthesis after cell division. PMID- 4222283 TI - Density gradient separation of sarcotubular vesicles and other particulate constituents of rabbit muscle. AB - Separation of particulate matter in rabbit muscle extracts by differential centrifugation leads, in first approximation, to the isolation of fraction I (15,000 to 41,000 g) and fraction II (41,000 to 150,000 g). The former consists mainly of sarcotubular material, actively transporting calcium ions, and displaying relaxation factor activity. The latter is heterogeneous, shows little calcium accumulation, and contains factors both inhibiting and activating myofibrillar ATPase. Fraction I is resolved by density gradient centrifugation into 2 main subfractions. The lighter one represents sarcotubular material in the best state of preservation, with biochemical activities stable for weeks in the cold. The heavier one may consist of the same material in a less well preserved form. Upon aging, it develops an activating activity toward myofibrillar ATPase, when the relaxing effect has declined. Fraction II is resolved by density gradient centrifugation into 3 or more fractions, with some variability. Relaxing activity in terms of inhibition of myofibrillar ATPase predominates among the lighter subfractions, increase of ATPase among the heavier. The intrinsic ATPase of fraction II is activated by calcium ions, but there is little or no bulk accumulation of calcium oxalate. Nevertheless, its limited calcium uptake seems to suffice to explain its relaxing activity. The particulate material contains mucopolysaccharide and lipid. Most of the lipid in fraction I is phospholipid; in fraction II this is less than half, if calculated as lecithin. The unfractionated material contains an adenylcyclase. There is no acetylcholine esterase. PMID- 4222284 TI - Poison ivy in Melbourne. PMID- 4222285 TI - [Long-term results of the treatment of Hodgkin's disease]. PMID- 4222287 TI - [Is Hodgkin's disease a curable disease?]. PMID- 4222286 TI - [Considerations on the place of radiotherapy]. PMID- 4222288 TI - [Can one know if Hodgkin's disease is curable? Statistical commentary]. PMID- 4222289 TI - [Statistical technic of analysis of the results of radiotherapy of Hodgkin's disease]. PMID- 4222290 TI - [Critical analysis of the concept of "curability" of Hodgkin's disease]. PMID- 4222291 TI - [Histopathologic diagnosis of Hodgkin's disease. Preliminary analysis of a blind study on 395 cases, by 3 pathologists of different nationalities]. PMID- 4222292 TI - [Segmentary radiotherapy of Hodgkin's disease. 1st results of 2 controlled therapeutic trials]. PMID- 4222293 TI - [Trial of combined radiotherapy and chemotherapy in the treatment of Hodgkin's disease]. PMID- 4222294 TI - [The role of chemotherapy in the long survival of Hodgkin's disease]. PMID- 4222295 TI - [Treatment of Hodgkin's adenopathies by 6 to 15 MeV electron therapy]. PMID- 4222296 TI - [Problem of the optimal dose in the radiotherapy of Hodgkin's disease]. PMID- 4222297 TI - [The prognosis of Hodgkin's disease according to the histologic type and the clinical stage. Role of the reactions of the host]. PMID- 4222298 TI - [Problem of the optimal dose in the irradiation of Hodgkin's disease]. PMID- 4222299 TI - [Extended irradiation in Hodgkin's disease. Early reactions]. PMID- 4222300 TI - [Proposition of a classification of the different clinical forms of Hodgkin's disease]. PMID- 4222301 TI - [Reflections on different means of classification of Hodgkin's disease. Role of so-called evolutive signs. Contribution of lymphography]. PMID- 4222302 TI - [Effects of lymphography on the clinical classification of Hodgkin's disease]. PMID- 4222303 TI - [Value of lymphography in Hodgkin's disease]. PMID- 4222304 TI - [Results of lymphography in malignant blood diseases at the anticancer center at Montpellier]. PMID- 4222305 TI - [Clinical classification of Hodgkin's disease. Its importance and the influence of general signs]. PMID- 4222306 TI - [Hodgkin's disease. Analysis of long term results]. PMID- 4222307 TI - [Long-term results of the treatment of Hodgkin's disease]. PMID- 4222308 TI - [Radiotherapy of Hodgkin's disease at Stanford University School of Medicine. Long-term results]. PMID- 4222309 TI - [Long-term results obtained by radiotherapy in Hodgkin's disease]. PMID- 4222310 TI - [Survival of more than 10 years in Hodgkin's disease]. PMID- 4222311 TI - [Radiotherapy of Hodgkin's disease. Foreword]. PMID- 4222312 TI - [Long-term results of the treatment of Hodgkin's disease]. PMID- 4222313 TI - [Factors influencing the long term survival of patients suffering from Hodgkin's disease]. PMID- 4222314 TI - [Relation between the degree of activity of Hodgkin's disease during the 1st 5 years and the fate of patients surviving 5 years]. PMID- 4222315 TI - Camping for crippled children. PMID- 4222316 TI - The effect of hydrocortisone on chondroitin sulfate production and loss by embryonic chick tibiotarsi in organ culture. PMID- 4222317 TI - Separation of acid polysaccharides by starch gel electrophoresis. PMID- 4222318 TI - The complex nature of phosphofructokinase - a nucleic acid containing enzyme. PMID- 4222319 TI - On the functional significance of the nucleic acid - protein complex of phosphofructokinase. PMID- 4222320 TI - Distribution of mucopolysaccharides in the human vascular tree. PMID- 4222321 TI - Physical education in a rehabilitation center. PMID- 4222322 TI - [Morphological and histochemical findings on pleural adhesions. (With special reference to quantitative changes of lipo-metabolic activity and mucopolysaccharide levels)]. PMID- 4222323 TI - Sulfur mustard: reaction with L-cells treated with 5-fluorodeoxyuridine. AB - After exposure to 5-fluorodeoxyuridine, L-cells are considerably more sensitive to the lethal effect of sulfur mustard than after they have been released from this block by addition of thymidine and allowed to proceed into the G2 phase of the division cycle. Nevertheless, for both populations, the amounts of mustard bound per cell and per nucleus (expressed as the amount of mustard per unit of protein) were the same. Likewise, the amounts of mustard bound per unit of DNA were the same for both populations. PMID- 4222324 TI - [The action "in vitro" of dehydroepiandrosterone on the biosynthesis of cortisol]. PMID- 4222325 TI - Further studies on the myofibrillar adenosine triphosphatase-inhibitory activity and the Mg++-dependent adenosine triphosphatase of the relaxing granules. PMID- 4222326 TI - Effect of sample site on fatty acid composition of adipose tissue. PMID- 4222327 TI - Uptake of fibrinogen and fibrinolytic enzymes by neoplastic tissue. PMID- 4222328 TI - Discharges of semitendinosus fusimotor neurones in the decerebrated and spinalized rabbit. PMID- 4222329 TI - Cardiac hypertrophy after muscular stress. Myocardial lipids modifications in rat. PMID- 4222330 TI - The role of cardiac enlargement in the production of musical pericardial sounds. PMID- 4222331 TI - [The effect of a combination of phenanthroline quinone plus iodochlorhydroxyquinoline in the prevention of dysvitaminosis caused by antibiotics]. PMID- 4222332 TI - Oxidative phosphorylation in Nitrobacter winogradskyi. PMID- 4222333 TI - The effect of sulphydryl-blocking reagents and of urea on the (Na+ + K+) activated enzyme system. PMID- 4222334 TI - [The concept of invalidism in some European legislation]. PMID- 4222335 TI - [Roentgen therapy of onyxis and perionyxis]. PMID- 4222336 TI - [Adverse effects and complications of BCG vaccination in young adults]. PMID- 4222337 TI - [Immunization by aerosols]. PMID- 4222338 TI - [Value of anti-diphtheria vaccination by purified anatoxin]. PMID- 4222339 TI - [Preservation of tetanus anatoxin by lyophilization. (Influence of lyophilization on the preservation of the immunizing capacity of a tetanus anatoxin subjected to various temperatures)]. PMID- 4222340 TI - [Group vaccinations by an automatic apparatus for injection by transcutaneous jet]. PMID- 4222342 TI - [Antigenic properties of experimental vaccines against Salmonella infections, obtained by gamma-irradiation of live bacteria]. PMID- 4222341 TI - [Effect of a free radical generator system on antigenicity. Applications to bacteria, cells and parasites]. PMID- 4222343 TI - [Importance of the lipids of the somatic antigen in vaccination against Salmonella infections]. PMID- 4222344 TI - [Paths opened by recent technics of attenuation of viral virulence by obtaining live vaccines]. PMID- 4222345 TI - [Current basis of the determination of the maximal doses of single or multiple antigens in the immune response]. PMID- 4222346 TI - [Influence of the danger of biological warfare on vaccinations to be performed in time of war]. PMID- 4222347 TI - [Influence of diphtheria vaccination in childhood on the present practice of diphtheria vaccination in the Army]. PMID- 4222348 TI - [Persistence of anti-tetanus immunity after school vaccinations. Effects on vaccinations in the Army]. PMID- 4222349 TI - [Immunization in the military service against infections caused by arboviruses]. PMID- 4222350 TI - [Current problems posed by vaccinations of young soldiers]. PMID- 4222351 TI - [Current problems posed by the use of vaccinations in tropical territory]. PMID- 4222352 TI - [Vaccinations in foreign armies]. PMID- 4222353 TI - [Postvaccinal nephropathies]. PMID- 4222354 TI - [Complications and adverse effects of vaccinations. The viewpoint of the allergist]. PMID- 4222355 TI - [Epidemiological study of typho-paratyphoid infections in vaccinated subjects in civilian life]. PMID- 4222356 TI - [Typho-paratyphoid infections in vaccinated subjects in military service. Clinical, epidemiological and immunological aspects. Apropos of 3,050 cases observed in 15 years in France and in North Africa]. PMID- 4222357 TI - [Contraindications to parenteral vaccinations]. PMID- 4222358 TI - [The results of vaccinations in the French Army]. PMID- 4222359 TI - The reticulocyte count in mongols. PMID- 4222360 TI - Ovalocytosis in normal and mentally retarded subjects. PMID- 4222361 TI - [The problem of eccentric fixation in strabic amblyopia]. PMID- 4222362 TI - [Orbito-ocular cancers in tropical Africa. Diagnostic and therapeutic problems]. PMID- 4222363 TI - [Measurement of the optic components of the eye of the newborn by ultrasonic echography]. PMID- 4222365 TI - [315 lesions of the orbit]. PMID- 4222364 TI - [The fine structure of certain corneal dystrophies]. PMID- 4222366 TI - [Infantile ophthalmology]. PMID- 4222367 TI - The absorption spectra of protoheme and heme a complexes with amino acids and related compounds. PMID- 4222368 TI - The effect of tripropyltin chloride on myosin A adenosine triphosphatase. PMID- 4222369 TI - Localization of mitochondrial adenosine triphosphatase activity in cultured human cells. PMID- 4222370 TI - Enzyme histochemistry of skeletal muscle. PMID- 4222371 TI - Acne vulgaris and systemic antibiotics. PMID- 4222372 TI - Antibiotics and the placebo reaction in acne. PMID- 4222373 TI - Objective evaluation of demethylchlortetracycline hydrochloride in the treatment of acne. PMID- 4222374 TI - Bacteriophage therapy in infective childhood asthma. PMID- 4222375 TI - Analysis of the check reflex. PMID- 4222376 TI - Reproduction in down's syndrome (mongolism): chromosomal study of mother and normal child. PMID- 4222377 TI - Actin-myosin interaction: inhibition of the myosin adenosine triphosphatase by actin. AB - In the absence of magnesium ion, the addition of actin to myosin in a 1 :4 ratio has a strong inhibitory effect on the adenosine triphosphatase activity, in contrast to the well-known activating effect of actin in the presence of magnesium ion. This finding suggests that both effects result from a conformational change in the active site of the myosin adenosine triphosphatase. PMID- 4222378 TI - [A rare case of diagnosis of renal tuberculosis]. PMID- 4222379 TI - [The significance of sensitization and desensitization in expert evaluation]. PMID- 4222380 TI - [Studies on chromium allergy, nickel allergy and cobalt allergy in cement and building trade workers]. PMID- 4222381 TI - [Group allergy to pyridine derivatives]. PMID- 4222382 TI - [Prevention and treatment of a beginning cement eczema with corticosteroid ointments. Experimental contribution]. PMID- 4222383 TI - Diurnal variation in some Krebs cycle enzymes in cactus (Nopalea dejecta) phylloclades. PMID- 4222384 TI - Studies on enzymic synthesis of cerebroside sulphate from 3'-phosphoadenosine-5' phosphosulphate. PMID- 4222385 TI - Oxidative enzymes in Escherichia coli plasma membrane. PMID- 4222386 TI - Exocellular deoxyribonuclease I of Penicillium chrysogenum: I--Partial purification & properties of the enzyme. PMID- 4222387 TI - Intracellular localization & characteristics of lactate dehydrogenase activity of Salmonella typhosa (NCTC 8385). PMID- 4222388 TI - Tricarboxylic acid cycle activity in a pseudomonad. PMID- 4222389 TI - The biochemistry of Vibrio cholerae: IV--Acid soluble nucleotide constituents. PMID- 4222390 TI - Effect of ultraviolet radiation on the oxidation of certain Krebs cycle substrates in Vibrio cholerae. PMID- 4222391 TI - Hormonal effect on certain glycolytic enzymes of rat mammary gland. PMID- 4222392 TI - Utilization of some amino acids by human malignant cervix uteri. PMID- 4222393 TI - Tricarboxylic acid cycle activity in human malignant cervix uteri. PMID- 4222394 TI - Immunochemical characterization of sheep plasma glycoprotein. PMID- 4222395 TI - Release of sialic acid from caseins of cow & buffalo milk by cow & buffalo rennets. PMID- 4222396 TI - Biochemical alterations in rat tissue in iron deficiency anaemia & repletion with iron. PMID- 4222397 TI - Interrelationship of dietary protein & vitamins on metabolism: I--Interdependence of the levels of certain B vitamins & dietary protein. PMID- 4222398 TI - Mode of action of psoralen in pigment production: 3--Photo-oxidation of dihydroxyphenylalanine in the presence of psoralen. PMID- 4222399 TI - Fatty acid composition of phosphatidyl ethanolamine of Mycobacterium tuberculosis. PMID- 4222400 TI - Polyguanylic acid & its effect on amino acid incorporation. PMID- 4222401 TI - Proteins in human milk. PMID- 4222402 TI - Electrophoretic studies on cytoplasmic proteins from human malignant cervix uteri. PMID- 4222403 TI - Chromosome structure in phage T4, II. Terminal redundancy and heterozygosis. PMID- 4222404 TI - Additional evidence for two kinds of heterozygotes in phage T4. PMID- 4222405 TI - The genetic structure of complementation heterozygotes. PMID- 4222406 TI - Synaptic activity in motoneurons during natural stimulation of muscle spindles. AB - Synaptic activity evoked in cat motoneurons during stretch stimulation of muscle spindles in the homonymous muscle has been studied by intracellular recording. A class of miniature excitatory postsynaptic potentials evoked by such physiologic stimulation results from activity in single group la spindle afferent fibers, and the criterion for identification is a predictable pattern of rhythmic occurrence of the synaptic potentials. Statistical examination of the amplitude distributions of this class of miniature synaptic potentials suggests that some group Ia fibers liberate a relatively large number of quantal excitatory postsynaptic potential units per fiber impulse. PMID- 4222407 TI - Mucopolysaccharides: N-acetylglucosamine- and galactose-6-sulfates from keratosulfate. AB - Galactose-6-sulfate and N-acetylglucosamine-6-sulfate were obtained pure from a partial acid hydrolyzate of corneal keratosulfate by paper chromatography and electrophoretic fractionation. These sugars were also present in hydrolyzates of skeletal keratosulfate. The distribution of the sulfate groups in the various keratosulfates might depend upon their source, and this distribution probably has important biological significance. PMID- 4222408 TI - A controlled trial of rehabilitation. PMID- 4222409 TI - Door handles for the disabled. An assessment of their suitability. PMID- 4222410 TI - Keratoelastoidosis marginalis of the hands. Synonyms: marginal keratoderma of palms; degenerative collagenous plaques of the hands. PMID- 4222411 TI - [On the differentiation of changes in the skin under various edematous conditions]. PMID- 4222412 TI - A new antibiotic against gonorrhea. PMID- 4222413 TI - Cytogenetic survey of 225 patients diagnosed clinically as mongols. PMID- 4222414 TI - [Connective tissue and resuscitation]. PMID- 4222415 TI - [Clinical observations on the activity of a new antistaphylococcal vaccine]. PMID- 4222416 TI - [Electrocardiographic findings in infantile cerebral diseases]. PMID- 4222417 TI - [Erythrodermatic reticulosis]. PMID- 4222418 TI - A survey of attitudes toward the training and employing of physically handicapped speech pathologists and audiologists. PMID- 4222419 TI - Water extrusion in isolated subcellular fractions. V. Adenosinetriphosphate hydrolysis by mitochondria during the reaction. PMID- 4222420 TI - The mucopolysaccharides of avian oviduct, egg, skin, and comb, and of porcine skin. PMID- 4222421 TI - Griseofulvin and lupus erythematosus. PMID- 4222422 TI - Action and indications for solid carbon dioxide therapy in dermatology. PMID- 4222423 TI - Vectorcardiographic criteria of left and right ventricular hypertrophy with the Frank system. PMID- 4222424 TI - Some histochemical observations on tissue of renal hypertensive animals. PMID- 4222425 TI - Further experiences with guanethidine--a clinical assessment of 103 patients. PMID- 4222426 TI - Trisomy D1 (13-15) in a Bantu child. PMID- 4222427 TI - [Leptospiral infections of the Lora type (australis serological group) in the Georgia SSR]. PMID- 4222428 TI - Neurons of intramural ganglia of the heart in its hyperfunction and hypertrophy. PMID- 4222429 TI - Relationship between structure, specificity and genes within the ABO and Lewis blood-group systems. PMID- 4222430 TI - Congenital and acquired anatomic variations, including degenerative changes of the lower lumbar spine; role in production of painful back and lower extremity syndromes. PMID- 4222431 TI - Children's orthopaedic surgery in the United States: historical trends. PMID- 4222432 TI - [Aleksandr Ivanovich Serebrov (on his 70th birthday)]. PMID- 4222433 TI - The role of Mg2+ in the contraction and adenosine triphosphatase activity of myofibrils. PMID- 4222434 TI - Metabolism in vivo of steroids in the canine ovary. PMID- 4222435 TI - Carbonic anhydrase distribution in rabbit lens. PMID- 4222436 TI - Some glycolytic enzymes and intermediates in the rabbit lens. PMID- 4222437 TI - The chemical specificity of the mucopolysaccharides of the cornea. PMID- 4222438 TI - In vitro studies of factors affecting penetration of duck erythrocytes by avian malaria (Plasmodium lophurae). PMID- 4222439 TI - Motor myoneural junctions on frog intrafusal muscle fibers. PMID- 4222440 TI - Demyelination regions of nerve fibers in frog muscle spindle as studied by serial sections for electron microscopy. PMID- 4222442 TI - Acid mucopolysaccharides in the Rask-Nielsen transplantable mouse mastocytoma. PMID- 4222441 TI - [Mucopolysaccharides in urine in the pediatric age. II. The Berry and Spinanger test as a screening test]. PMID- 4222443 TI - 3',5'-diesters of 5-fluoro-2'-deoxyuridine: synthesis and biological activity. PMID- 4222444 TI - [The significance of abnormal QRS amplitudes in the electrocardiogram]. PMID- 4222445 TI - Backache due to osteoporosis in an industrial population. A survey of 481 patients. PMID- 4222446 TI - [Combined right and left ventricular hypertrophy in infancy and childhood. Electrocardiographic and vectorcardiographic studies with special reference to the QRS wave complex]. PMID- 4222447 TI - [Prognosis of chronic cor pulmonale]. PMID- 4222448 TI - Pedodontics--preventive and personal. PMID- 4222449 TI - Spondylopathy. A clinical study of backache in the aged. PMID- 4222450 TI - The 99th Annual Session dedicated to Siskin brothers. PMID- 4222451 TI - [Plan for the dental treatment of 1st year school children and distribution of resources in the Central Hospital Area]. PMID- 4222452 TI - Repression of Staphylococcus aureus in associative culture. AB - The growth of Staphylococcus aureus MF 31 was suppressed when grown in association with Streptococcus diacetilactis and other lactic streptococci. The data indicated that the initial proportion of staphylococci present in the medium was of less importance than the depletion of vital nutrients. Investigation revealed that factors present in Yeast Nitrogen Base medium could reverse the inhibition which was due to antagonism. The major factor found was nicotinamide, and further study revealed that the biological availability of this compound was influenced by the pH of the medium. The addition of nicotinamide to depleted media with careful control of the pH resulted in increased growth of S. aureus in the test system. Further data indicated that additional factors may affect the degree of growth by S. aureus in depleted media. PMID- 4222453 TI - Bacteriophage inhibition in staphylococci. PMID- 4222454 TI - [On the release of the central effects of nicotine on breathing and efferent vagus innervation in the rat]. PMID- 4222455 TI - Cardiovascular actions of the hypotensive agent, N, N-Diallylmelamine (U-7720). PMID- 4222456 TI - [On the effects of alpha-methyl-dopa on the pyrocatecholamine content in guinea pig organs]. PMID- 4222457 TI - [Kidney function after temporary ligation of the renal artery]. PMID- 4222458 TI - The preparation of microsomes. PMID- 4222459 TI - Species differences in the hydroxylation of aniline and N-ethylaniline by liver microsomes. PMID- 4222460 TI - [The effects on circulation of 5'-substituted adenosine derivatives]. PMID- 4222461 TI - A note on "cancer-susceptible" and "cancer-resistant" genotypes: implications for cancer detection and research. PMID- 4222462 TI - An epidemiological approach to infant mortality in Omaha and Douglas County 1960 1964. PMID- 4222463 TI - Beverage electrolytes at the Bishop Clarkson Memorial Hospital, Omaha, Nebraska. PMID- 4222464 TI - Congenital strictures of the esophagus. PMID- 4222465 TI - Fluid balance--intake and output charts, a revised form. PMID- 4222466 TI - The Penrose industrial health centre. PMID- 4222467 TI - Effect of glucocorticoids upon the mucopolysaccharide content of human skin. PMID- 4222468 TI - Quinethazone photosensitivity dermatitis. PMID- 4222469 TI - Corynebacterium acnes. Presence of complement fixing antibodies to corynebacterium acnes in the sera of patients with acne vulgaris. PMID- 4222470 TI - [Camille Duverger (1882-1965)]. PMID- 4222471 TI - Fungi in nails. PMID- 4222472 TI - [Demonstration of cortical control of the dynamic fusimotor fiber activity in cats by the pyramidal approach]. PMID- 4222473 TI - Recovery of muscle spindle activity in cats after cerebellar ablation. PMID- 4222474 TI - Workmen's compensation--a long journey forward. PMID- 4222475 TI - Proteolytic activity in muscles of old animals. PMID- 4222476 TI - [The problem of longevity and the social-hygienic views of I. R. Tarkhnishvili (Tarkhanov)]. PMID- 4222477 TI - [Considerations on fibrinolysis with special reference to a biological inhibitor of plasmin]. PMID- 4222478 TI - [Inflammatory tumors of Braun and Schloffer]. PMID- 4222479 TI - [Electrocardiographic diagnosis of left ventricular hypertrophy: utility of the orthogonal electrocardiogram]. PMID- 4222480 TI - Flavin-linked dehydrogenation of ether glycols by cell-free extracts of a soil bacterium. AB - Payne, W. J. (University of Georgia, Athens), and R. L. Todd. Flavin-linked dehydrogenation of ether glycols by cell-free extracts of a soil bacterium. J. Bacteriol. 91:1533-1536. 1966.-Cell-free extracts of bacterium TEG-5 grown on tetraethylene glycol dehydrogenated a variety of ether glycols and nonylphenoxy and secondary alcohol ethoxy derivatives. Nicotinamide nucleotides did not serve as electron acceptors, but ferricyanide was effective. Dialysis of crude extract depressed activity with tetraethylene glycol, which was restored then by flavine adenine dinucleotide (FAD) or boiled extract supernatant fluid (BES) but not by other flavins. Precipitatation of extract protein at pH 4.0 at 80% ammonium sulfate saturation dissociated FAD and yielded an inactive fraction. Activity was restorable by FAD and BES but not by other flavins. Ethylene glycol was not dehydrogenated by the acid ammonium sulfate fraction with FAD. Atabrine inhibited tetraethylene glycol oxidation, and the inhibition was relieved by FAD but not by other flavins. Tergitols which have sulfated ethoxy side chains on secondary alcohols were not dehydrogenated, but those with free ethoxy side chains on identical alcohols were. PMID- 4222481 TI - Rapid separation of mucopolysaccharides by salt-gradient ion-exchange paper chromatography. PMID- 4222482 TI - Adenosine triphosphatase activity in 2 strains of Staphylococcus aureus differing in radiosensitivity. PMID- 4222483 TI - Pediatric dentistry under general anesthesia. PMID- 4222484 TI - Symposium: Analgesia in dental practice. 4. Analgesia in pedodontic practice. PMID- 4222485 TI - [Some problems concerning the epidemiology of tuberculosis in 1 of the Caspian lowland regions]. PMID- 4222486 TI - Judicial vs. medical notice: coronary artery disease in industry. PMID- 4222487 TI - The electromyogram in the evaluation of medicolegal and workmen's compensation cases. PMID- 4222488 TI - [Ophthalmologic problems in facial or cranio-facial injuries]. PMID- 4222489 TI - Principles of public health importance in the management of a subhuman primate colony. PMID- 4222490 TI - Schistosome dermatitis in association with rice growing in the northern territory of Australia. PMID- 4222491 TI - [Extraction and morphological characterization of a basement membrane fraction from the renal cortex in the rat]. PMID- 4222492 TI - [Long-term results obtained in Hodgkin's disease treated by radiotherapy alone]. PMID- 4222493 TI - [Factors intervening in the long survival of Hodgkin's disease]. PMID- 4222494 TI - [Method for the determination of total blood mucopolysaccharides]. PMID- 4222495 TI - [Mucopolysaccharide changes in the endometrium during the rise and drop of estrogen levels]. PMID- 4222496 TI - Wheelchair users--a study in variation of disability. PMID- 4222497 TI - [On possible relations between cytogenetic anomalies and cytochemical alterations. Alkaline leukophosphatase in mongolism]. PMID- 4222498 TI - The pattern of contact dermatitis due to occupation. PMID- 4222499 TI - [Surgical technic in venter pendulus]. PMID- 4222500 TI - Hexosephosphate formation and the regulation of glycolysis in muscle. PMID- 4222501 TI - [Peritoneoscopy in human hepatic fascioliasis]. PMID- 4222502 TI - [Considerations on the control of infectious diarrhea]. PMID- 4222503 TI - [The problem of definitions in the field of mental health. Definitions applicable to epidemiologic studies]. PMID- 4222504 TI - [Isolation of the rabies virus from vampire bats in the State of Sao Paulo, Brazil]. PMID- 4222506 TI - [The role of public health laboratories in the diagnosis of venereal diseases]. PMID- 4222505 TI - [Clinical and laboratory diagnosis of venereal diseases]. PMID- 4222507 TI - Influence of induced tuberculin allergy followed by induced Arthus reaction on each other, in rabbits. PMID- 4222509 TI - [On relations of dermatitis seborrhoides in infants to exudative diathesis]. PMID- 4222508 TI - Coupling of ATP-hydrolysis with contraction of isolated myofibrillar fragments. PMID- 4222510 TI - [Determination of sorbitol dehydrogenase and creatine phosphokinase in the serum of lathyritic rats treated and non-treated with prednisone]. PMID- 4222511 TI - [Differential diagnosis of the electrocardiogram, by means of discriminant function, especially of left ventricular hypertrophy]. PMID- 4222512 TI - [The appointed school dentist]. PMID- 4222513 TI - [Histopathological and histochemical arguments in support of the concept of the allergic pathogenesis of multiple sclerosis]. PMID- 4222514 TI - [Preliminary extraction of the cataractous crystalline lens in cases of retinal detachment]. PMID- 4222515 TI - [A further unilateral case of mosaic degeneration of Bowman's membrane associated with a band-shaped degeneration on a malformed eye]. PMID- 4222516 TI - [Value of spurachoroid puncture in the treatment of choroid detachment appearing during the immediate postoperative period of a fistulizing operation]. PMID- 4222517 TI - [Iridocyclectomy for cancer of the anterior uvea]. PMID- 4222518 TI - [Possibilities of a selective application of enzymatic zonulolysis in cataract cryoextraction]. PMID- 4222520 TI - [Cytological and clinical study of conjunctival allergy]. PMID- 4222519 TI - [Surgical technic for ocular prosthesis contention in cases of an intolerant conjunctival cavity]. PMID- 4222521 TI - [The optical correction of aphakia. I. Examination of the aphakic]. PMID- 4222522 TI - [The adaptation of soft lenses]. PMID- 4222523 TI - The effects of ethyl chloride on the muscle spindles of the triceps surae of the rabbit. PMID- 4222524 TI - Kurloff body formation in the guinea pig lymphocyte. PMID- 4222525 TI - [Pilar pytiriasis rubra improved by applications of fluocinolone acetonide cream under occlusive dressing]. PMID- 4222526 TI - [Respiratory function in pneumoconiosis patients from southern Kirghizia mines]. PMID- 4222527 TI - [Peripheral blood picture in newborn infants and mothers in medium range mountain regions in Kirghiz]. PMID- 4222528 TI - [Maternal mortality in the Republic and means for its further decrease]. PMID- 4222529 TI - [Role of the vaccination center in controlling diphtherial morbidity in the city Kok-Iangak]. PMID- 4222530 TI - [Clinical course of acute brucellosis in Kirghizia]. PMID- 4222531 TI - [A case of ornithosis in Kirghizia]. PMID- 4222532 TI - Structure of heparitin sulfate in tissues of the Hurler syndrome. PMID- 4222533 TI - Influence of rifamycins on glycolysis of rat brain. PMID- 4222534 TI - [On the cause of species differences in digitalis sensitivity]. PMID- 4222535 TI - Effects of ethanol on na, K, mg-stimulated microsomal ATPase activity. PMID- 4222536 TI - Adenosinetriphosphatase activity in synaptic vesicles of rat brain. PMID- 4222537 TI - Inhibition of testosterone stimulation of microsomal hexobarbital metabolism by 17-alpha-methyl-B-nortestosterone (SK&F 7690). PMID- 4222538 TI - Preventable occupational dermatoses. PMID- 4222539 TI - The family physician and Workmen's Compensation. Legal aspects. PMID- 4222540 TI - Disability without disease or accident. PMID- 4222541 TI - [Experimental substantiation of diagnosis of thrombosis by means of I-131-labeled fibrinolysin]. PMID- 4222542 TI - [Protective effect of combined injection of fibrinolysin and heparin against thrombogenesis in animals during the pre-thrombotic state and in experimental atherosclerosis]. PMID- 4222543 TI - Study on frequency of allergic manifestations and skin reactivity in children with Down's syndrome. PMID- 4222544 TI - Protein metabolism requisite for cell division in Tetrahymena pyriformis. PMID- 4222545 TI - [The handicapped child in the normal school]. PMID- 4222546 TI - [The physically handicapped child in high schools]. PMID- 4222547 TI - [Remedial teaching aspects of handicapped children care]. PMID- 4222548 TI - [Local treatment of backache]. PMID- 4222549 TI - [Modern symptomatic therapy of acne]. PMID- 4222551 TI - [Hemoglobin H]. PMID- 4222550 TI - [Preliminary note on the action a new anthelmintic in dracunculosis. Attempted preventive eradication]. PMID- 4222552 TI - [Burkitt's tumor in 1966]. PMID- 4222553 TI - [Leukocyte alkaline phosphatase in patients with tumors or malignant hemopathies]. PMID- 4222554 TI - [Periodic structures in the eosinophil and neutrophil granulations of the polynuclear leukocytes of human blood]. PMID- 4222555 TI - [On the variability of action of phytohemagglutinin in peripheral blood culture]. PMID- 4222556 TI - [Endogenous formation of carbon monoxide and hemoglobin catabolism]. PMID- 4222557 TI - [Some considerations on porcine leukoses]. PMID- 4222558 TI - [Introduction to the study of blood platelet enzymes]. PMID- 4222559 TI - [Blood platelet enzymes]. PMID- 4222560 TI - [Blood platelet enzymes and function during their preservation]. PMID- 4222561 TI - [Leukocyte enzymes]. PMID- 4222562 TI - [Importance of cytochemical technics for the study of modifications of the enzyme equipment of leukocytes in leukemia]. PMID- 4222563 TI - [Enzymes of the blood in anthropology]. PMID- 4222564 TI - Lipolytic activity of rat lungs in dependence on age. PMID- 4222565 TI - The development of arginase and ornithine-transcarbamylase activities in the liver of rats. PMID- 4222566 TI - Changes of proteolytic activity of proteins following denervation in the anterior and posterior latissimus dorsi of the chicken. PMID- 4222567 TI - The effect of adrenalectomy and starvation on arginase and ornithine transcarbamylase activities in the liver of rats during development. PMID- 4222568 TI - Liberation from and uptake of non-esterified fatty acids into adipose tissue of rats with different work output. PMID- 4222569 TI - Vesico-ureteral reflux in rabbits. PMID- 4222570 TI - The relation between spontaneous rhythmical variation in vasomotor excitability and conditioning of the vasomotor reflex to deep inspiration. PMID- 4222571 TI - Development of the steady potential and high frequency impedance of the cerebral cortex in guinea-pig embryos. PMID- 4222572 TI - A contribution to the analysis of the pulse rate during a load and recovery. PMID- 4222573 TI - The relationship between calcium and chlortetracycline in the body. PMID- 4222574 TI - Retraction and firmness of the fibrin clot. PMID- 4222575 TI - Factors affecting the proteolytic activity in denervated muscle. PMID- 4222576 TI - [The place of rehabilitation in the treatment of rheumatic and post-traumatic backache]. PMID- 4222577 TI - Rehabilitation of the disabled worker. I. An overall view of rehabilitation and workmen's compensation in New Jersey. PMID- 4222578 TI - [Mucopolysaccharides in urine in the pediatric age. I. The turbidimetric test according to the Dorfman method as a screening test]. PMID- 4222580 TI - Pathological studies on mucopolysaccharide metabolism: experimental lathyrism and mucopolysaccharides. PMID- 4222579 TI - [Adenosine triphosphatase activity in normal persons and patients with hemolytic anemia]. PMID- 4222581 TI - [Presence of neutral and acid mucopolysaccharides coinciding with the Golgi apparatus, in the multifid glands of Helix pomatia]. PMID- 4222582 TI - [Histiocytosis X in the light of our observations]. PMID- 4222583 TI - [Some aspects of the microbial flora in dental caries. Comparative study of the microbial flora in the oral cavity of school-children based on date from a field study in the Azerbaijan SSR]. PMID- 4222584 TI - [Has the significance and incidence of recognized occupational diseases changed?]. PMID- 4222585 TI - [Acute increase of hearing during treatment of endocrine hearing disorder]. PMID- 4222586 TI - [Chromosome conditioned oligophrenic states (mongolism, Patau syndrome, Edwards syndrome)]. PMID- 4222587 TI - Efficacy of 'dequinol' in the treatment of bovine balantidiosis. PMID- 4222588 TI - Determination of glucosamine and galactosamine by gas chromatography. PMID- 4222589 TI - Effect of metal-complexing agents on mucopolysaccharide sulfate biosynthesis. PMID- 4222590 TI - [On a case of desmoid of the abdominal wall with double localization]. PMID- 4222591 TI - The relation between DNA and protein synthesis in mouse fibroblasts. PMID- 4222592 TI - [Changes in the blood properdin level in normal and irradiated animals under the effect of a mucopolysaccharide preparation from cattle spleen]. PMID- 4222594 TI - The impaired aged. A follow-up study of applicants rejected by a voluntary home. PMID- 4222593 TI - Rehabilitation of the elderly patient. PMID- 4222595 TI - Seborrhoeic dermatitis. PMID- 4222596 TI - [Use of metal alloys in orthopedics. The metallurgist's viewpoint]. PMID- 4222597 TI - [MacMurray's osteotomy in the treatment of coxarthrosis]. PMID- 4222598 TI - [Treatment of Monteggia's fractures in adults]. PMID- 4222599 TI - [Treatment by screwing of osteochondritis dissecans of the lower end of the femur]. PMID- 4222600 TI - [Surgical treatment of losses of substance of the tibia by implantation of the fibula]. PMID- 4222601 TI - [On a rare case of traumatic dislocation of the hip in a child associated with a complete epiphysial detachment and a fracture of the femoral head nucleus]. PMID- 4222603 TI - [Disease-related or symptom-directed pharmacotherapy?]. PMID- 4222602 TI - [Elephantiasis and oseous malformations limited to the buttock and right thigh in von Recklinghausen's neurofibromatosis]. PMID- 4222604 TI - [Special genetic problems of neurology]. PMID- 4222605 TI - [A new pyramidal sign which proves valuable for the diagnosis of latent hemiplegia]. PMID- 4222606 TI - [Pointed wave status in reflex epilepsy caused by apoplexy. Contribution to the valency of rhymthic-synchronous pointed wave activity in the EEG]. PMID- 4222607 TI - [On cerebral manifestations of mycoses]. PMID- 4222608 TI - [Music therapeutic experiences in chronic schizophrenics]. PMID- 4222609 TI - [Gamma encephalographic findings in temporal lobe epileptics]. PMID- 4222610 TI - Mucopolysaccharides in synovial fluid detection of chondroitin sulphate. PMID- 4222611 TI - [The university and community health services. The 1965 Bronfman lecture]. PMID- 4222612 TI - [Some considerations on brucellosis in Haiti]. PMID- 4222613 TI - [Investigation on the presence of Brucella in the milk supply of the city of Azul, Argentina]. PMID- 4222614 TI - [Mass vaccination against measles in Chile with Enders attenuated virus vaccine]. PMID- 4222615 TI - [Professional education and training of personnel in the field of venereal diseases]. PMID- 4222616 TI - [Teaching on venereal diseases]. PMID- 4222617 TI - [Observations on public sanitation services in Latin America]. PMID- 4222618 TI - [Control of venereal diseases]. PMID- 4222619 TI - [The ventricular gradient in digitalis treatment]. PMID- 4222620 TI - Effect of a sulfated mucopolysaccharide (R01-8307) on the zona glomerulosa of the rat adrenal gland. PMID- 4222621 TI - [Experiments in the use of the Ca-phosphate method at pH 7.5 for the histochemical determination of adenosine triphosphatase]. PMID- 4222622 TI - Urinary acid mucopolysaccharides. PMID- 4222623 TI - [On dermatitis seborrhoides in infants and its relations to exudative diathesis]. PMID- 4222624 TI - Comparison of therapeutically important antirheumatics on the basis of experimental results. PMID- 4222625 TI - Influence of a cartilage bone marrow extract on mucopolysaccharide metabolism of cells cultured in vitro. PMID- 4222626 TI - Reproductive biology--2000. PMID- 4222627 TI - The peptides of amniotic fluid. PMID- 4222628 TI - Nebraska history and medicine: A centennial. PMID- 4222629 TI - The causes of labor. PMID- 4222630 TI - Evaluation of the fetus in utero. PMID- 4222631 TI - Cellular production of gonadal steroid hormones. PMID- 4222632 TI - Ultrasound in physiotherapy. PMID- 4222633 TI - [Occupational skin diseases. (A review of journals from 1961 to 1963)]. PMID- 4222634 TI - [Some contradictory problems of the terminology, nomenclature and classification of occupational dermatoses]. PMID- 4222635 TI - [The treatment of patients with acneiform eruption]. PMID- 4222636 TI - [Experience in microsporosis control]. PMID- 4222637 TI - [Dispensary treatment of patients with chronic dermatoses in rural areas]. PMID- 4222638 TI - [Control of pyodermatitis in the Kirov Watch Plant I in Moscow]. PMID- 4222639 TI - Vitamin C deficiency and connective tissue. V. Fractionation of acid mucopolysaccharides in carrageenan-granulomas. PMID- 4222640 TI - Vitamin C deficiency and connective tissue. IV. Determinations of mucopolysaccharides and collagen in carrageenan-granulomas. PMID- 4222641 TI - Our experience with the diagnosis of anomalies of the pulmonary venous return and their surgical treatment. PMID- 4222642 TI - Isolated (primary) chylopericardium. Diagnosis and surgical treatment. PMID- 4222643 TI - Dogger Bank itch: survey of trawlermen. PMID- 4222644 TI - Arsenicals for asthma. PMID- 4222645 TI - An inhibitor of cholesterol biosynthesis and the alveolar macrophages. AB - An accumulation of lipid material was observed in the alveolar macrophages of animals treated per os with an inhibitor of cholesterol biosynthesis (trans-1, 4 bis) (2-dichlorobenzyl-aminomethyl) cyclohexane dihydrochloride: AY-9944). This lipid is probably 7-dehydro-cholesterol which is a precursor of cholesterol and accumulates in various organs, especially in the lungs. In the rats and pigs the reaction is limited to the alveolar macrophages which are expectorated or degenerate. In dogs some of the alveolar macrophages are also expectorated while others continue to collect a cholesterol-like lipid until large crystals form, which provoke the formation of giant cells and later fibrocytes, giving rise to "cholesterol granulomata". PMID- 4222646 TI - Feed manufacturers and the veterinarian. PMID- 4222647 TI - Immunofluorescence study of wild rabies virus and antibody. AB - A concentrate of wild rabies antibody was prepared from hyperimmune serums of three dogs refractory to wild rabies. The animals resisted repeated intramuscular injections of large doses of wild rabies virus in emulsions of whole brain, in emulsions of submaxillary salivary glands, and in emulsified mixtures of brain and submaxillary glands taken from naturally rabid dogs. The antibody was conjugated with fluorochrome and then absorbed by a procedure that gave "cell free" working solutions of fluorescent antibody. The procedure entailed parallel absorption steps with minced pathological canine submaxillary glands from (1) naturally rabid dogs (these glands contained specific, undegraded, natural antigens of live wild rabies virus plus nonspecific substances and antigens) and (2) nonrabid dogs from a rabies endemic region (these glands contained nonspecific substances and antigens). Extracts from submaxillary glands of the three naturally rabid dogs and one nonrabid dog were stained with a cell-free solution of the fluorescent antibody. The glands of the rabid dogs contained fluorescent aggregates of intense green spherical and filamentous particles. When nonfluorescent canine hyperimmune serum was incubated with rabies-containing submaxillary extract, the rabies antigens were quenched. When nonfluorescent equine fixed virus antiserum was incubated with such extracts, the aggregates still retained bright fluorescence. PMID- 4222648 TI - The role of the food and drug directorate in the control of veterinary drugs. PMID- 4222649 TI - [Clinical picture of erythema fixum generalisatum caused by PAS hypersensitivity observed in 41-year-old male with pulmonary tuberculosis after a prolonged treatment with antitubercular agents (INH and PAS)]. PMID- 4222650 TI - Psychology of children's dental treatment. PMID- 4222651 TI - Pedodontics--a graduate discipline. PMID- 4222652 TI - Disabled children and rehabilitation. PMID- 4222653 TI - [Radiotherapy of Hodgkin's disease. Foreward]. PMID- 4222655 TI - [Promoting the oral health of the child]. PMID- 4222654 TI - [Study of the distribution of haptoglobin types in the population of Haut Languedoc by starch gel electrophoresis with 3 constant parameters]. PMID- 4222656 TI - Orthodontics, pedodontics and the general practitioner. PMID- 4222657 TI - Development of the resistance to general stagnant anoxia (ischemia) in dogs. PMID- 4222658 TI - [Activities of the public health dentistry illustrated by dental and tested experiences]. PMID- 4222659 TI - Human low-dosage parenteral methotrexate therapy. A controlled toxicity study. PMID- 4222660 TI - The use of gas-liquid chromatography in the analysis of neutral monosaccharides in hydrolysates of gastric mucopolysaccharides. AB - 1. Conditions are described for the separation and estimation of the neutral monosaccharides obtained on acidic hydrolysis of human gastric mucopolysaccharides. 2. The technique involves the formation of the trimethylsilyl derivatives of the sugars and the analysis of these by gas-liquid chromatography. 3. The monosaccharides estimated in gastric mucopolysaccharides by this technique were l-fucose, d-mannose, d-galactose and d-glucose. 4. The analytical values for glucose and fucose obtained by this method agreed well with values obtained by the glucose oxidase and thioglycollic acid methods respectively. 5. Evidence is presented which clearly indicates that gas-liquid chromatography is a faster, more sensitive and more convenient technique for the measurement of these compounds than any other in use at present. PMID- 4222662 TI - Why the Apollo contamination control handbook? PMID- 4222661 TI - Distribution of sodium-plus-potassium-stimulated adenosine-triphosphatase activity in isolated nerve-ending particles. AB - 1. A rapid method for the isolation of nerve-ending particles from brain is described. This involved the centrifugation of the large-granule fraction over a discontinuous density gradient consisting of 3% (w/v) and 13% (w/v) Ficoll dissolved in 0.32m-sucrose. The results of the biochemical as well as morphological identification of nerve-ending particles are given. 2. Approx. 20% of the (Na(+)+K(+))-stimulated adenosine-triphosphatase activity originally present in the cerebral grey-matter suspension was recovered in the fraction consisting principally of large nerve-ending particles (approx. 1mu in diameter). The activity of the adenosine triphosphatase/mg. of protein in the nerve-ending fraction approximated to that in the small-granule fraction after the treatment with glycol ether diamine-tetra-acetic acid. The conclusion was drawn that the synaptic structure, supposedly the limiting membrane of the nerve-ending particle, is one of the feasible sites of localization of the (Na(+)+K(+)) stimulated adenosine-triphosphatase activity in cerebral tissues. Adenosine triphosphatase in purified cerebral mitochondria was not stimulated by Na(+). 3. No qualitative differences were found between the (Na(+)+K(+))-stimulated adenosine-triphosphatase activities exhibited by the nerve-ending particles and by the cerebral small-granule fraction with respect to pH-dependence, cation requirements and susceptibility to ouabain. PMID- 4222663 TI - Open-end clean room at Collins Radio flexible, expandable and economical. PMID- 4222664 TI - Is your cleaning solvent compatible? Asks speaker. PMID- 4222665 TI - Applying "downflow" to dust-fume control in a plastics facility. PMID- 4222666 TI - Contamination control for a precision photogrammetric lab. PMID- 4222667 TI - Understanding fluctuations in airborne contamination. PMID- 4222668 TI - Hospital use of sterile "patient isolators". PMID- 4222669 TI - Maximizing functional abilities of the disabled. PMID- 4222670 TI - An endogenous mechanism of increased vascular permeability in allergic inflammation: purification of permeability factors newly isolated from Arthus lesion and their biologic significance. PMID- 4222671 TI - An endogenous mechanism of increased vascular permeability in allergic inflammation: reproduction of vascular response by Arthus permeability factor in rabbit skin. PMID- 4222672 TI - [Contribution to the study of Cantrell's syndrome with special reference to the cardiopathy]. PMID- 4222673 TI - [Physiology and biochemistry of prolonged contraction. Experimental investigation with special reference to the m. retractor byssi in Mytilus edulis]. PMID- 4222674 TI - p-Aminohippurate and N-methylnicotinamide transport in dog renal slices--an evaluation of the counter-transport hypothesis. PMID- 4222675 TI - The mechanism of reflex irradiation. PMID- 4222676 TI - [Agenesis of the abdominal musculature associated with other malformations]. PMID- 4222677 TI - Biosynthesis of steroid sulfates by normal human testis. PMID- 4222678 TI - Measurement of plasma 11-deoxy-17-ketosteroid sulfates by gas-liquid chromatography. PMID- 4222679 TI - [Effectiveness and methods of the treatment of syphilitic lesions of the central nervous system at the Pyatigorsk health resort]. PMID- 4222681 TI - [Sanitary state of the atmospheric air and the hygienic problems of long-term planning of health resort towns of Caucasian mineral waters]. PMID- 4222680 TI - [Effect of Semigorsk mineral water on the secretory function of the pancreas in dogs]. PMID- 4222682 TI - [Multiple cutaneous ossification foci following acne vulgaris]. PMID- 4222683 TI - Changing concepts in pedodontic education. PMID- 4222684 TI - [On the eczematogenic effect of mansonia-wood]. PMID- 4222685 TI - The production of phage structural proteins in single cells of Escherichia coli infected with phage T4. PMID- 4222686 TI - [On the establishment of a Sub-Department of Dental Pediatrics in the Department of Stomatology at the Medical Faculty of the Humboldt University of Berlin]. PMID- 4222687 TI - [The detergents and hospital hygiene]. PMID- 4222688 TI - [Pick-Herxheimer disease with erythemato-nodular lesions]. PMID- 4222689 TI - [Comparative results of different surgical treatments of rhinophyma]. PMID- 4222691 TI - Intensive care of the coronary patient. PMID- 4222690 TI - [Observations on a new method for the differentiation of mycobacteria by the use of culture media containing nicotinamide]. PMID- 4222692 TI - Roentgenologic contrast studies in vascular disease. PMID- 4222693 TI - Psychoactive drugs: review and overview. Review of sites of action, uses, dosage, side effects and contraindications of psychoactive drugs with proposed classification and suggested rules for prescribing. PMID- 4222694 TI - The role of pelvic lymphadenectomy in the surgical management of early stage 1 carcinoma of the cervix. PMID- 4222695 TI - Severe bronchial asthma: its pathology and treatment. PMID- 4222696 TI - Electrocardiogram of the month. PMID- 4222697 TI - Tetanus. PMID- 4222698 TI - Blood pressure and toxemia of pregnancy. PMID- 4222699 TI - Do not despair. PMID- 4222700 TI - Pharmacologic interference with mast cell degranulation induced by BW 48/80. PMID- 4222701 TI - [On the problem of preventive digitalization]. PMID- 4222702 TI - [Interrelation between barbiturates, piperazine and GABA in the membrane of crayfish muscles]. PMID- 4222703 TI - [True hexobarbital tolerance]. PMID- 4222704 TI - [The effects of acetazolamide on the increase of plasma calcium values following administration of parathormone]. PMID- 4222705 TI - [On the effect of drugs on neurons of the hippocampus following microelectrophoretic administration]. PMID- 4222706 TI - Modern management of hair and scalp disorders. PMID- 4222707 TI - [Staphylococcal lysotyping. Incidence of type 29 in hospitalism]. PMID- 4222708 TI - [Minus variants and anomalies in the molar region of the human teeth]. PMID- 4222709 TI - An investigation into the content of elastic tissue and muscle tissue in the aorta of some big and small mammals. PMID- 4222710 TI - [Audiologic and phonologic study in subjects affected by mongolism]. PMID- 4222711 TI - [Do not give away a fortune]. PMID- 4222712 TI - The influence of new guanidine derivatives on adrenergic nerve endings, ganglionic transmission and neuromuscular junction. PMID- 4222713 TI - Potentiated premedication with ataraxics prior to stomatologic treatment of children and adolescents with psychiatric symptomatology. (Preliminary report). PMID- 4222715 TI - [Training and use of auxiliary public health personnel in Latin America]. PMID- 4222714 TI - [Thermostable products forming during fibrinogen proteolysis by plasmin]. PMID- 4222716 TI - [Notes on the control of tuberculosis in Nicaragua]. PMID- 4222717 TI - [National planning and the construction of maternal and child hygiene standards in Latin America. Integration of the hygiene and medical care activities at a functional level]. PMID- 4222718 TI - [Epidemiologic study of a disease believed to be encephalitis in the region of the highlands of Guatemala]. PMID- 4222719 TI - Plasminogen-free proactivator B obtained from human plasma. PMID- 4222720 TI - [Occupational diseases of the skin and their prevention. A dermatological report on the Pforzheim industry]. PMID- 4222721 TI - Stimulation of the coronary collateral circulation by lidoflazine (R 7904). PMID- 4222722 TI - [The excitatory effects of desoxyephedrine (Pervitin) on the tonic spinal motoricity in cats]. PMID- 4222723 TI - [N-hydroxylation of sulfanilamide to p-hydroxylaminobenzolsulfonamide by liver microsomes]. PMID- 4222724 TI - [Studies on the relations between quinidine-like and beta-adrenolytic effects of 1-(3-methlphenoxy)-2-hydroxy-3-isopropylaminopropane (Ko 592)]. PMID- 4222725 TI - [Glycogen content and phosphorylase activity of white mouse brains under the influence of reserpine]. PMID- 4222726 TI - [Effects of chelating agents on the excretion of cadmium in cadmium poisoning]. PMID- 4222727 TI - [On the structural specificity of permeation-promoting capillary-active polycations]. PMID- 4222728 TI - [On the mechanism of circulatory effects of isotonic sodium chloride solutions]. PMID- 4222729 TI - [On the different way of modification of resistance and capacitance vessels by various sympathomimetics]. PMID- 4222730 TI - [Increase of noradrenaline effects by tyramine]. PMID- 4222731 TI - [On the mechanism of sympathomimetic action of some aliphatic amines]. PMID- 4222732 TI - The antagonistic effects of sodium and calcium on the action potential of guinea pig papillary muscle. PMID- 4222733 TI - [Teratogenic effect of cyclophosphamide during the embryonic developmental phase in rats]. PMID- 4222734 TI - [On the effect of teratogenic drugs on the early stages of antenatal rat development]. PMID- 4222735 TI - [Iron resorption in isolated small intestinal preparations of normal and anemic rats]. PMID- 4222736 TI - [Effect of various ligands on iron transport and binding in isolated intestinal preparations of normal and anemic rats]. PMID- 4222737 TI - [Incorporation of thymidine into deoxyribonucleic acid of mitochondria]. PMID- 4222738 TI - [On the effect of aconitine on the impulse activity in afferent fibers from lung dilation receptors]. PMID- 4222739 TI - [The effect of 5-hydroxytryptamine on the resorption of tritiated water (HTO) from the rat colon in vivo]. PMID- 4222740 TI - [On the problem of pathogenesis of vagus reflex bradykinin tachypnea]. PMID- 4222741 TI - [Biosynthesis, distribution and excretion of 3-acetyl-6-pryidone, a metabolite of 3-acetylpyridine]. PMID- 4222742 TI - [The decrease of the kininogen content of plasma in toxic, anaphylactic and anaphylactoid shock]. PMID- 4222743 TI - [Substance P in the retina]. PMID- 4222744 TI - [Substance P content and capillary permeability in substantia nigra extracts]. PMID- 4222745 TI - [Obtaining substance P from the lipid extract of brain tissue]. PMID- 4222746 TI - [Central and peripheral effects of cholinomimetics and their dependence on lipoid solubility]. PMID- 4222747 TI - [Dependence of pharmacodynamically produced changes of the arteriovenous oxygen difference of the heart on the extracellular pH]. PMID- 4222748 TI - [Central effect of reserpine on the circulatory reflexes of the carotid sinus]. PMID- 4222749 TI - Skin disease in the Venda. PMID- 4222750 TI - Receptor potentials and impulse generation in the isolated spindle during controlled extension. PMID- 4222751 TI - The dual role of sensory systems: detection and setting central excitability. PMID- 4222752 TI - Response of the isolated muscle spindle to different rates of stretching. PMID- 4222753 TI - [Hypertrophy-ECG and anatomical substrate, seen by the example of left ventricular hypertrophy]. PMID- 4222754 TI - [Simultaneous determination of free cortisol, esterified dehydroepiandrosterone and androsterone in peripheral blood]. PMID- 4222755 TI - Technique for separation and estimation of androsterone, aetiocholanolone and dehydroepiandrosterone by use of thin-layer chromatography. PMID- 4222756 TI - [On foot arthrodeses]. PMID- 4222757 TI - Some aspects of the aetiology of acne vulgris. PMID- 4222758 TI - Occupational and nonoccupational exposures to asbestos. PMID- 4222759 TI - Dust diseases and workmen's compensation. U.S. Department of Labor, Bureau of Labor Standards, August 1964. PMID- 4222760 TI - [Mucopolysaccharides and metastatic calcifications]. PMID- 4222761 TI - Amino acid metabolism in patients with Hurler's syndrome. PMID- 4222762 TI - Release of plasminogen activator by the isolated perfused dog kidney. PMID- 4222763 TI - [Clinical study of a new neuroplegic drug, Dixyrazine, in a double-blind experiment with subsequent serial analysis]. PMID- 4222764 TI - [Aesthetic treatment of acne among Asian nations in the tropics]. PMID- 4222765 TI - The future of pedodontics. PMID- 4222766 TI - Preparation of the specialists in pedodontics. PMID- 4222767 TI - Hospital procedures in the care of the handicapped child. PMID- 4222768 TI - An injection procedure for the child dental patient. PMID- 4222769 TI - Rubber dam technique in pedodontics. PMID- 4222770 TI - Stainless steel: its use in pedodontics. PMID- 4222771 TI - Plastics in pedodontics. PMID- 4222772 TI - Pulpal therapy in primaryand young permanent teeth. PMID- 4222773 TI - Traumatized primary teeth. PMID- 4222774 TI - Pediatric exodontia. PMID- 4222776 TI - The versatile occlusal dental x-ray film. 3. A new pedodontic survey. PMID- 4222775 TI - Treatment of dentitions affected by hereditary amelogenesis and dentinogenesis imperfecta. PMID- 4222777 TI - A new cortical area receiving input from group I muscle afferents. PMID- 4222779 TI - 6-alpha-hydroxylation in human placenta perfusion. PMID- 4222778 TI - Alkylation of a brain transport adenosinetriphosphatase at the cardiotonic steroid site by strophanthidin-3-haloacetates. PMID- 4222780 TI - Conversion of dehydroepiandrosterone sulfate to androst-5-enediol-3-sulfate by soluble extracts of rat testis. PMID- 4222781 TI - Natriuretic action of certain adrenocortical androgens. PMID- 4222782 TI - [A method for the identification of erythrocyte-bound incomplete antibodies in hemolytic disease of the newborn infant]. PMID- 4222783 TI - [The effect of diffusion time, antigen and antiserum concentrations in the immunoelectrophoresis of rat's serum]. PMID- 4222784 TI - [The reciprocal heterotypic hemagglutination inhibition reaction with adenovirus types 8, 9 and 10]. PMID- 4222785 TI - Some problems encountered in the assay of complement. PMID- 4222786 TI - Crystallization of the Dick toxin. PMID- 4222787 TI - [Hemolytic shock. VII. Hematological studies]. PMID- 4222788 TI - [Studies on the specificity of hemagglutination in virus hepatitis]. PMID- 4222789 TI - [Problems of treatment of deciduous teeth (caries and pulp diseases)]. PMID- 4222790 TI - Sodium-potassium dependent adenosine triphosphatase of mammalian reticulocytes and mature red blood cells. PMID- 4222791 TI - In vitro testosterone synthesis by rat testicular tissue. PMID- 4222792 TI - Newborn organ abnormalities. A guide to abnormal maternal glucose metabolism. PMID- 4222793 TI - [Children as patients]. PMID- 4222794 TI - Investigation of certain links in the photoenzymochemical chain of processes in photoreceptors. PMID- 4222795 TI - Pedodontic utilization of contributions made by operative dentistry, dental materials, and prosthodontics. PMID- 4222796 TI - [On a difference in their effect on the heart of mono- and bisguanyl hydrazones]. PMID- 4222798 TI - N-Hydroxylation of 2-aminofluorene in the guinea pig and by guinea pig liver microsomes in vitro. PMID- 4222797 TI - [The effect of tricyclic antidepressants on rabbit 5-hydroxytryptophan hyperthermia]. PMID- 4222799 TI - [On the intestinal effect of digitoxin, penta-acetylgitoxin and other acetylgitoxins]. PMID- 4222800 TI - [On the mechanism of action of the lipolytic effect of physostigmine]. PMID- 4222801 TI - [On the relations of effects of adrenaline, a beta-adrenolytic and quinidine on the contraction power and calcium metabolism of the guinea pig atrium]. PMID- 4222802 TI - [Some properties of the RNA polymerase reaction in warm-blooded animal mitochondria]. PMID- 4222803 TI - [The effect of cardiac glycosides on reflex bradycardia]. PMID- 4222804 TI - The hydrolysis of acetanilide and some of its derivatives by enzymes in the microsomal and soluble fraction prepared from livers of various species. PMID- 4222805 TI - [Serotonin release from isolated granules of enterochromaffin cells]. PMID- 4222806 TI - [The effect of some histamine-chelating heavy metals on the histamine contraction of the guinea pig ileum]. PMID- 4222807 TI - [On albumin-copper binding, examined by the reaction of the guinea pig ileum]. PMID- 4222808 TI - [The effects of drugs on calcium content and calcium-45 exchange of the smooth muscles of guinea pig taenia coli]. PMID- 4222809 TI - [Characterization and purification of peptic kinin-yielding fragments (PKF) as well as "Pepsitocin" from bovine serum kininogen]. PMID- 4222810 TI - [On enzymatic splitting of peptic kinin-yielding fragments (PKF) and of bovine serum kininogen]. PMID- 4222811 TI - [Structure determination of kinin-yielding peptides from bovine serum kininogen]. PMID- 4222812 TI - [The effect of beta receptors blocking substances on the K-42 exchange of the guinea pig atrium increased by adrenaline]. PMID- 4222814 TI - [Physiologic bases of acclimatization to heat. Medico-military applications]. PMID- 4222813 TI - [The sequelae of icterogenic hepatitis]. PMID- 4222815 TI - [The treatment of chronic colitis and colopathies with a new combination of bismuth, gum, oxyquinolein and meprobamate]. PMID- 4222816 TI - [Recent aspects of respiratory physiology during transverse accleration]. PMID- 4222818 TI - Local authority welfare services for the handicapped. PMID- 4222817 TI - Viral-induced bacterial toxins. PMID- 4222819 TI - Congenital beta-lipoprotein deficiency. PMID- 4222820 TI - [The polarographic detection of dehydroepiandrosterone in urine for the purpose of determining radiation responses of organism in tumour therapy]. PMID- 4222821 TI - [Epidemiology of epidemic hepatitis (Botkin's disease)]. PMID- 4222822 TI - The XXXXY chromosome anomaly: report of three new cases and review of 30 cases from the literature. AB - The majority of abnormal sex chromosome complexes in the male have been considered to be variants of Klinefelter's syndrome but an exception should probably be made in the case of the XXXXY individual who has distinctive phenotypic features. Clinical, radiological and cytological data on three new cases of XXXXY syndrome are presented and 30 cases from the literature are reviewed. In many cases the published clinical and radiological data were supplemented and re-evaluated. Mental retardation, usually severe, was present in all cases. Typical facies was observed in many; clinodactyly of the fifth finger was seen in nearly all.Radiological examination revealed abnormalities in the elbows and wrists in all the 19 personally evaluated cases, and other skeletal anomalies were very frequent. Cryptorchism is very common and absence of Leydig's cells may differentiate the XXXXY chromosome anomaly from polysomic variants of Klinefelter's syndrome. The relationship of this syndrome to Klinefelter's syndrome and to Down's syndrome is discussed. PMID- 4222824 TI - Federal legislation and the smaller health care facility. More and better services needed for the physically disabled. PMID- 4222823 TI - The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man. AB - The mechanisms of the aldosterone-inhibiting and antihypertensive actions of heparin and certain other sulfated mucopolysaccharides were investigated in 13 hypertensive patients. N-formyl chitosan polysulfuric acid (RO 1-8307) was used rather than heparin because of its low anticoagulant activity. RO 1-8307 lowered aldosterone secretion in one patient with proved and one with probable primary aldosteronism; this indicates that the mucopolysaccharide does not inhibit aldosterone secretion via the renin-angiotensin mechanism. In six hypertensive patients RO 1-8307 caused a fall in the secretion of aldosterone and its probable immediate precursor, 18-hydroxycorticosterone; therefore it does not act at the last step in the synthesis of aldosterone. RO 1-8307 produced a prolonged clinical and biochemical remission in the two patients considered to have primary aldosteronism but did not influence blood pressure in five of seven patients in whom excessive aldosterone was probably not a major factor in the hypertension. It is concluded that the antihypertensive action of RO 1-8307, and perhaps of heparin as well, is largely due to suppression of aldosterone secretion. PMID- 4222825 TI - Enzymes leading to mucopolysaccharide synthesis in granulation tissue. PMID- 4222826 TI - [The umbilicus in plastic surgery of the abdomen. Transposition or reconstruction]. PMID- 4222827 TI - [Isolation of a 2nd polypeptide with leukotactic and permeation-promoting effects from calf thymus]. PMID- 4222828 TI - [Enzyme defects as a cause of different mydriatic effects of atropine and cocaine in rabbits]. PMID- 4222829 TI - [Dependence of the contraction effect of phosphatidic acid and acetylcholine on taenia coli upon the extracellular ion content]. PMID- 4222830 TI - [Studies on the frog skin for insight into the mechanism of action of diuretics on transport-active membranes]. PMID- 4222831 TI - [The effect of some centrally acting drugs on the synaptic transmission in the crayfish muscle]. PMID- 4222832 TI - [Significance of feed take-up for the genesis of ketosis in alloxan diabetic rats]. PMID- 4222833 TI - [On the effect of adrenaline on the cellular Ca-metabolism in the guinea pig atrium]. PMID- 4222834 TI - [Problems on hypersensitivity reactions of the skin caused by medications]. PMID- 4222835 TI - [Histochemical demonstration of absorption in the salivary gland]. PMID- 4222836 TI - Histochemical studies on the growing human tibial cartilage. PMID- 4222837 TI - [Adrenocortical hormones and biosynthesis of acid mucopolysaccharides. II. UDPG:NAD oxidoreductase activity in the subcutaneous granuloma of adrenalectomized rats treated with cortisone, corticosterone and aldosterone]. PMID- 4222838 TI - [On the release of biogenic amines from blood platelets by animal poisons]. PMID- 4222839 TI - [The effect of cobalt gluconate and of the dicobalt salt of ethylenediaminetetraacetic acid (Co-2 EDTA) on the brain metabolism of normal and cyanide-poisoned mice]. PMID- 4222840 TI - [Quantitative comparison of the positively inotropic and of the toxic effect of several cardiac glycosides]. PMID- 4222841 TI - [On the origin of plasma histaminase in the anaphylactic shock in guinea pigs]. PMID- 4222842 TI - [On the significance of calcium and magnesium ions for the storage of adrenal medulla hormones]. PMID- 4222843 TI - [Methamoglobin formation by p-hydroxylamino- and p-nitrosobenzenesulfonamide in umbilical cord and adult erythrocytes]. PMID- 4222844 TI - [Iodide uptake of the guinea pig thyroid and trachea during and after chronic perchlorate treatment]. PMID- 4222845 TI - [On the localization of central mechanisms of respiratory efforts of the suffocating pigeon]. PMID- 4222846 TI - [Mechanism of action of some chemical mutagens]. PMID- 4222847 TI - [Modification of the cellular control mechanism by drugs]. PMID- 4222848 TI - [Clinical aspects of chemotherapy of malignant tumors and malignant systemic diseases]. PMID- 4222849 TI - [The function of nucleic acids in cellular metabolism]. PMID- 4222850 TI - [Basocellular epithelioma superimposed on rhinophyma]. PMID- 4222851 TI - [Some aspects of improving the organization of first aid stations]. PMID- 4222852 TI - [Experience with the airplane transportation to central regional hospitals in mountain areas]. PMID- 4222853 TI - [Statistical data on basic aspects of the development of public health in the RSFSR in early months of 1965]. PMID- 4222854 TI - [Physical development of newborn infants from indigenous population groups in the Ob Arctic Region]. PMID- 4222855 TI - [Method of indirect study of the contraction of intrafusal muscular fibers consecutive to the stimulation of single fusimotor fibers in cats]. PMID- 4222856 TI - [Peculiarities of stomatologic emergencies in children]. PMID- 4222857 TI - [Role of A. A. Iovskii and A. P. Neliubin in the development of medicinal and galenic forms]. PMID- 4222859 TI - Silent period in patients with parkinsonian rigidity. PMID- 4222858 TI - [Accident and insurance medicine]. PMID- 4222860 TI - [Pages from the history of the I. M. Balinskii Hospital]. PMID- 4222861 TI - [Borderline forms of mental diseases in the works of St. Petersburg psychiatrists of the last century]. PMID- 4222862 TI - [Role of Leningrad psychiatrists in the development of child psychiatry]. PMID- 4222863 TI - Histological characteristics of mesothelioma associated with asbestos. PMID- 4222864 TI - Active transport and enzymes of the erythrocyte membrane under protein deprivation. AB - 1. Starvation for 3 days causes membrane damage of the rat erythrocyte manifested by several alterations. The adenosine-triphosphatase activity is decreased but that of acetylcholinesterase is not affected. 2. The ouabain-sensitive adenosine triphosphatase activity increases at the expense of the non-sensitive enzyme moiety. 3. The Rb(+) uptake is not altered but the galactose transport is accelerated by the stated experimental conditions. 4. The modifications induced by starvation do not recover on re-feeding. PMID- 4222865 TI - [Unpublished notes of Claude Bernard on the physiologic properties of arrow poisons (curare, upas, strychnine and others)]. PMID- 4222867 TI - Temperate phages influencing lipase production by Staphylococcus aureus. PMID- 4222868 TI - [Studies on electrocardiogram of right ventricular hypertrophy in chronic cor pulmonale]. PMID- 4222869 TI - Possible relationship between aortic acid mucopolysaccharides and species susceptibility to experimental atherosclerosis. PMID- 4222870 TI - [Prostaglandine in a darmstoff preparation from frog intestine]. PMID- 4222871 TI - [On the influence of chelating agents on the excretion and the behavior of mercury in acute mercury poisoning]. PMID- 4222872 TI - [Inhibition of the uptake or alpha-methylnoradrenaline by the heart by sympathomimetic amines]. PMID- 4222873 TI - [Experimental studies on staphylococcal pneumonia. (XI). Studies on the rate of migration and the phagocytotic ability of leucocytes in experimentally induced in staphylococcal pneumonia]. PMID- 4222874 TI - Newer fibrinolytic agents. PMID- 4222875 TI - [The general standard principle in the quantitative serodiagnosis of syphilis. 3. The testin of the amboceptor by the state and the introduction of an amboceptor unit]. PMID- 4222876 TI - [Some aspects of traffic injuries in the city and district of Riazan]. PMID- 4222877 TI - Biochemical studies in Huntington's chorea. II. Composition of blood lipids. PMID- 4222878 TI - 1-Phosphofructokinase from an anaerobe. PMID- 4222879 TI - The occurrence of gamma-aminobutyric acid in human tissues other than brain. PMID- 4222880 TI - A peculiar mode of muscular innervation in Amphioxus. Light and electron microscopic studies of the so-called ventral roots. PMID- 4222881 TI - [Investigations on dextran therapy in ileus]. PMID- 4222882 TI - Action of 5-fluorodeoxyuridine on human chromosomes. PMID- 4222883 TI - In vitro susceptibility of UC-18 staphylococci. PMID- 4222884 TI - [The behavior of acid mucopolysaccharides in diabetes]. PMID- 4222885 TI - Megaloblastic anaemia developing during treatment of epilepsy. PMID- 4222886 TI - Mucopolysaccharides as a localized factor of egg-shell stability. PMID- 4222887 TI - ATP-ase as inhibitor of lysokinase and plasminoplastin activators of fibrinolysis in vitro. PMID- 4222888 TI - Sulphate conjugation during development, in human, rat and guinea pig. PMID- 4222889 TI - Sulphate conjugation during pregnancy and under the influence of cortisone. PMID- 4222890 TI - [Influence of testosterone and progesterone on the adrenal cortex of the monkey Macacus irus F. Cuv]. PMID- 4222891 TI - [Electron microscope study of the "Wharton's jelly" of the human umbilical cord during the 3rd and 4th month of embryonic development]. PMID- 4222892 TI - [Experimental starting of rumination]. PMID- 4222893 TI - [Estimation of the mental load by use of physiological indices. I. Cardiac rate]. PMID- 4222894 TI - [Simple technic permitting the exclusion or the reintegration of the adrenal glands during successive aggressions]. PMID- 4222895 TI - [Seasonal changes in the physiological characteristics of cardiac glycogen in frogs]. PMID- 4222896 TI - [4-Butyrolactone and cell permeability]. PMID- 4222898 TI - [Influence exerted by chlordiazepoxide on the behavior of the praying mantis]. PMID- 4222897 TI - [Monoamine oxidase and cholinesterases in the brain: influence of psychotropic agents]. PMID- 4222899 TI - [Influence of temperature on the development of experimental infection of the newborn mouse by Coxsackie virus]. PMID- 4222900 TI - [Inhibition of the development of the sea urchin egg after the action of actinomycin D on the ovocyte]. PMID- 4222901 TI - [Distribution of basic nuclear and cytoplasm proteins in the developing ovocyte of Paracetrotus lividus (Lmk)]. PMID- 4222902 TI - [On some enzyme activities of early placenta cultures]. PMID- 4222903 TI - [Study of a tumor induced in rats by implantation of polyurethane sponge impregnated with methylcholanthrene]. PMID- 4222904 TI - [Abnormal localizations of megakaryocytes in rats bearing experimental tumors]. PMID- 4222905 TI - [Study of actions evoked in the olivary body in cats]. PMID- 4222906 TI - [Study of visual evoked responses during sleep with eye movements in young children]. PMID- 4222907 TI - [Experimental study of a hyperglycemic sulfonamide, diazoxide]. PMID- 4222908 TI - [Diazoxide experimentally exercises an inhibitory action on the basal secretion of insulin]. PMID- 4222909 TI - [Acute cardiovascular effects of several monoamine oxidase inhibitors in dogs]. PMID- 4222910 TI - [Prolongation of the cardiac positive inotropic action of ouabain after administration of estrogens]. PMID- 4222911 TI - [Action of acetic acid on the sporulation of Saccharomyces cerevisiae Hansen]. PMID- 4222912 TI - [General microscopic anatomy of the hypophyso-pituitary complex of 2 reptiles: Varanus ex. exanthematicus (Bosc) and Varanus n. niloticus (Linne)]. PMID- 4222913 TI - [On the activation of induced diuresis by the stimulation of the cardio accelerator nerves]. PMID- 4222914 TI - [Electroretinogram of a Lemurian: Galago senegalensis]. PMID- 4222915 TI - [Ultrastructural changes of the pars distalis of the guinea pig hypophysis after thyroidectomy]. PMID- 4222916 TI - [Anomalies of the sarcoplasmic reticulum and proliferation of tubules in the muscle in familial periodic paralysis]. PMID- 4222917 TI - [Influence of actinomycin D on the virgin egg of Artemia salina under artificial activation conditions]. PMID- 4222918 TI - [Effect of neutral deoxyribonuclease on the synthesis of total nuclear proteins and deoxyribonucleic acids in fibroblasts cultivated in vitro]. PMID- 4222919 TI - [Comparative study of the action of the ethero-petrol fraction of extracts of various organs of the rat on the isolated frog heart]. PMID- 4222920 TI - [Effects of hemolysates on the coagulation of rabbit plasma]. PMID- 4222921 TI - [Action of calcium ions on adrenalin-induced arterial hypertension in rats]. PMID- 4222922 TI - [Biochemical changes in the hair of young Africans suffering from kwashiorkor]. PMID- 4222923 TI - [Action of strontium ions on cardiac muscle]. PMID- 4222924 TI - [On precipitating substances, similar to autoantibodies, which appear in the blood of rabbits injected with streptococci]. PMID- 4222925 TI - [Immunologic tolerance induced in dogs by single or repeated neonatal injections of bone marrow from unrelated adult donors]. PMID- 4222926 TI - [Apropos of the action of histamine on carbonic anhydrase]. PMID- 4222927 TI - [An induced tumor: ecchondroma]. PMID- 4222928 TI - [The stages of tumorization by 3,4 benzopyrene studied by means of a stathmokinetic test]. PMID- 4222929 TI - [Comparative study of the effects of thiocarbohydrazide and chemically modified deoxyribonucleic acids on reticulosarcoma ST4 and leukemia L 1210]. PMID- 4222930 TI - [Histochemical study of induced and grafted pulmonary tumors in mice]. PMID- 4222931 TI - [Effects of oestradiol in the slow-worm (Anguis fragilis L.) embryo]. PMID- 4222932 TI - [Effects of x-rays on the young slow-worm (Anguis fragilis L.) embryo]. PMID- 4222933 TI - [Behavior of the chondriome hepatocytes in trypsinated cultures]. PMID- 4222934 TI - [Action of thyroid products on the mitochondrial uptake of Sr2+]. PMID- 4222935 TI - [Ontogenetic study of transamination activity in the brain and blood of the newborn rabbit]. PMID- 4222936 TI - [Influence of combined thalamic and mesencephalic lesions on avoidance conditioning in rats]. PMID- 4222937 TI - [Absence of an action of the caudal neurosecretory system in Teleosts in the secretion of gas from the swim bladder]. PMID- 4222938 TI - [Metabolic properties of Enterobacteria spheroplasts induced by 6 aminopenicillanic acid]. PMID- 4222939 TI - [Mediastinal lymphoma in Swiss mice receiving urethane. 3. Adaptation to the graft. Histologic and hematologic study]. PMID- 4222940 TI - [Action of ionizing radiation on the HeLa cell. II. Electron microscope study]. PMID- 4222941 TI - [Comparative studies of the structure of human transferrin and lactotransferrin. "Fingerprinting" of the protease hydrolysates of both glycoproteins]. PMID- 4222942 TI - [Study of the physiochemical properties and the reduction products of a gamma M cryoglobulin]. PMID- 4222943 TI - [Summer camps for crippled children]. PMID- 4222944 TI - Compensable psychogenic backache. PMID- 4222945 TI - The effect of alum-precipitated pyridine ragweed extract on guinea pigs. II. Comparison of passive cutaneous anaphylaxis with Arthus reactivity after single low dose. PMID- 4222947 TI - Clinical manifestations of strongyloidiasis. PMID- 4222946 TI - The Brenner tumor. PMID- 4222948 TI - Electrocardiogram of the month. PMID- 4222949 TI - The treatment of acne. PMID- 4222950 TI - [Clinical, psychopathological and biochemical investigations on combined psychoses]. PMID- 4222951 TI - [Aphasias in polyglots. Contribution to the dynamics of speech loss as well as to the localization problem of these disorders]. PMID- 4222952 TI - [On rhythmic myoclonias in a case of cerebellar systemic atrophy]. PMID- 4222953 TI - [Effect of high pressures on some properties of myosin]. PMID- 4222955 TI - [Premedication in dental treatment of children]. PMID- 4222954 TI - [Fractionation and properties of early products of proteolysis of fibrinogen with the use of plasmin]. PMID- 4222956 TI - [Separation and determination of vitamin PP and of nicotinic acid in broth cultures]. PMID- 4222957 TI - Research studies in physical fitness as applied to atypical youth. PMID- 4222958 TI - [Clinical and therapeutical considerations concerning 800 cases of lumbo sciatica]. PMID- 4222959 TI - 7-alpha-hydroxylation of delta-5-pregnenolone and of its conjugates by rat-liver microsomes. PMID- 4222960 TI - Specific reaction of local anesthetics with phosphodiester groups. PMID- 4222961 TI - Does squinting matter? PMID- 4222962 TI - Schooling for the handicapped. PMID- 4222963 TI - Studying 16,000 children. PMID- 4222964 TI - Comparative responses of regulative and determinate embryos to metabolic inhibitors. PMID- 4222965 TI - In vitro studies on 35S-sulfate incorporation into the acid mucopolysaccharides of chick embryo cardiac jelly. PMID- 4222966 TI - Acid mucopolysaccharide content of the cardiac jelly of the chick embryo. PMID- 4222968 TI - Gene and phenocopy: selection experiments and tests with 6-aminonicotinamide. PMID- 4222967 TI - Differentiation of transplanted larval salivary glands of Drosophila hydei in adults of the same species. PMID- 4222970 TI - "One's" therapy of seborrheic dermatitis. PMID- 4222969 TI - [Experience in the use of psychotherapy in a climatic ward for patients with sleep disorders]. PMID- 4222972 TI - Current topical therapy for acne vulgaris. PMID- 4222971 TI - Seborrheic dermatitis. PMID- 4222973 TI - Fundamentals in acne management. PMID- 4222974 TI - Current embryology and treatment of gastroschisis and omphalocele. PMID- 4222975 TI - Correlation between staphylococcal serotypes with 263-1 factor and phage group 1. PMID- 4222976 TI - An attempt at biochemical characterisation of histologically well defined tumours. PMID- 4222977 TI - Excitation-contraction coupling and control of cardiac contractility. PMID- 4222978 TI - Demonstration of intercoronary anastomoses in human hearts with a low viscosity perfusion mass. PMID- 4222979 TI - [Clinical function test of the heart]. PMID- 4222980 TI - Quantitative and qualitative cytochemical studies on the Amphiuma basophil leucocyte. PMID- 4222981 TI - Stoichiometry of proton translocation through the respiratory chain and adenosine triphosphatase systems of rat liver mitochondria. PMID- 4222982 TI - Case records of the Massachusetts General Hospital. Case 31-1966. PMID- 4222983 TI - [Retrospective view of the international sports festival for the physically handicapped]. PMID- 4222984 TI - [Basic concepts on proteolytic enzymes and their clinical applications--with special reference to plasmakinin metabolism]. PMID- 4222985 TI - Assessment of disability. PMID- 4222986 TI - Compensation to nurse for herniated disk. PMID- 4222987 TI - [Investigations on the mechanism of induction of lysogenic bacteria. IX. The temperature dependence of induction by thymine deficiency and mitomycin C]. PMID- 4222988 TI - Cardiac impulse in hypertrophic obstructive cardiomyopathy. PMID- 4222989 TI - The effect of bile salts on oxygen consumption, oxidative phosphorylation and ATP ase activity of mucosal homogenates from rat jejunum and ileum. PMID- 4222990 TI - An oral digit symbol test. PMID- 4222991 TI - The Knox cubes as a test of memory and intelligence with male adults. PMID- 4222993 TI - Leukocyte alkaline phosphatase in mongolism. PMID- 4222992 TI - [Effects of application of diluted alcohol on the nerve. I. Comparative dynamographic and histologic studies on the decerebrate cat]. PMID- 4222994 TI - Control of myocardial contraction: the sensitivity of cardiac actomyosin to calcium ion. AB - The control by calcium ion of the adenosine triphosphatase activity of cardiac actomyosin is similar to that of white skeletal actomyosin. This finding indicates that the slower contraction and relaxation of heart muscle do not reflect different levels to which free calcium ion concentration around the myofibrils must be adjusted during contraction and relaxation and suggests a mechanism whereby myocardial contractility may be regulated. PMID- 4222995 TI - Role of the B-complex vitamins on intestinal activity in dogs. PMID- 4222996 TI - Low back pain in men receiving workmen's compensation. AB - In Ontario, only about 10% of compensation patients with low back pain are disabled more than six weeks and hence tend to have chronic complaints. Six hundred and twenty-three such patients were studied to determine the distribution of diagnoses and to test the effectiveness of various programs of conservative therapy.Two hundred and thirteen patients were assigned in rotation to one of four treatments. The results were inconclusive. In 70% of these, the pain was due to intervertebral disc degeneration with added trauma.Two hundred and sixteen patients were assigned randomly to a treatment involving mild exercise, or one with vigorous exercise. Neither was found to be superior. In 76% of these, the pain was due to disc degeneration with added trauma.Using 194 patients, the results of treatment in the Compensation Board Rehabilitation Centre were compared with those obtained by treatment at home. Satisfactory improvement was achieved in 15 of 95 treated at home, and in 42 of 99 in the Centre. The failure of treatment in six of each 10 cases indicates that present-day methods of management of such patients are unsatisfactory. PMID- 4222997 TI - 1965 achievements of Workmen's Compensation Board reviewed. PMID- 4222998 TI - Effect of vitamin A on mucopolysaccharides in myxovirus-infected cells. PMID- 4223000 TI - Early developmental staging as a prophecy index in Down's syndrome. PMID- 4222999 TI - [Phage typing and antibiogram of staphylococci isolated from acute infantile enteritis]. PMID- 4223002 TI - Mosaicism in Down's syndrome: studies in a child with an unusual chromosome constitution. PMID- 4223001 TI - Alzheimer's disease and senile dementia as seen in mongoloids: neuropathological observations. PMID- 4223003 TI - Down's syndrome associated with family history of malignancy in mothers of affected children. PMID- 4223005 TI - Skin disease from colour developers. PMID- 4223006 TI - The role of dental auxiliaries in child dental health. PMID- 4223004 TI - Reproductive performance of mothers of mongols. PMID- 4223007 TI - Inhibition of cell division and cell elongation in higher plants by inhibitors of DNA synthesis. PMID- 4223008 TI - The nature of inclusions in erythrocytes of turkeys treated with diethylstilbestrol. PMID- 4223009 TI - Hepatitis attributed to sulfamethoxazole. PMID- 4223010 TI - [Study of the blood clearance and urinary elimination of glycerylaminophenaquine. Chromatographic study of its urinary metabolites]. PMID- 4223011 TI - [Contribution to the electrocardiographic diagnosis of biventricular hypertrophy]. PMID- 4223012 TI - Myofibrillar adenosine triphosphatase activity of human heart tissue in congestive failure: effects of ouabain and calcium. PMID- 4223013 TI - Inhibition of protein synthesis in cardiac hypertrophy and its relation to myocardial failure. PMID- 4223014 TI - Diagnostic signs in compressive cardiac disorders. Constrictive pericarditis, pericardial effusion, and tamponade. PMID- 4223015 TI - Studies on the fibrinolytic enzyme system in obesity. AB - Plasma fibrinolytic activity, inhibitors of fibrinolysis, and fibrinogen were estimated in 34 subjects of varying ratio of observed to standard weight. The inverse relationship between fibrinolytic activity and the ratio of observed to standard weight was confirmed. No significant correlation was found between anti plasmin or anti-urokinase and the ratio of observed to standard weight. It was therefore concluded that the decreased plasma fibrinolytic activity in obese subjects is due to decreased production of plasminogen activator rather than to excessive inhibition. PMID- 4223016 TI - Combined hypertrophy. PMID- 4223017 TI - Exhaustion of atrial fibrillation in aneurysmatic dilatation of the left atrium. PMID- 4223018 TI - Philosophy of operation and medical policy of the Meeting Street School. PMID- 4223019 TI - Special education for handicapped children--where and when to use it. PMID- 4223020 TI - [Fibrinolysin]. PMID- 4223021 TI - [Backache and electromyography]. PMID- 4223022 TI - Massive pulmonary embolism. VI. Prevention by partial occlusion of the inferior vena cava. PMID- 4223023 TI - [Behavior of the free nucleotides of the myocardium in experimental cardiac hypertrophy]. PMID- 4223024 TI - [Statistical consideration of the degenerative back]. PMID- 4223025 TI - [The role of mucopolysaccharides in the pathogenesis of atherosclerosis]. PMID- 4223026 TI - Antibody types in experimental animals and their biologic properties. PMID- 4223027 TI - Histochemical studies on the red, white and intermediate muscle fibers of some skeletal muscles. I. Succinic dehydrogenase activity and physiological function of intercostal muscle fibers. PMID- 4223029 TI - Electron microscopic studies on the tumor induced by adenovirus type 12. PMID- 4223028 TI - Histochemical studies on the red, white and intermediate muscle fibers of some skeletal mescles. II. The capillary distribution on three types of fibers of some skeletal muscles. PMID- 4223030 TI - Physical analysis of the energy transducing reaction in mitochondria. PMID- 4223031 TI - Multiple keratoacanthomata. Response of a case to systemic chemotherapy. PMID- 4223032 TI - [Biochemistry of inflammation. II. Concluded]. PMID- 4223033 TI - [A practical guide for treating children]. PMID- 4223034 TI - [Recent trends in pedodontics in the United States]. PMID- 4223035 TI - A simple method for the determination of urinary dehydroepiandrosterone. PMID- 4223037 TI - Microbiological formation of 3-beta,7-alpha,15-alpha-trihydroxyandrost-5-en-17 one. PMID- 4223036 TI - Determination of androsterone and dehydroepiandrosterone sulfates in human serum by gas-liquid chromatography. PMID- 4223038 TI - [Contribution to the problem of postpubertal oogenesis in the domestic cat (Felis domestica). Histological and autoradiographic study]. PMID- 4223039 TI - [On the development and differentiation of the fore-stomach epithelium of the domestic mouse (Mus musculus L. 1758)]. PMID- 4223040 TI - Chemotherapy studies in an animal tumor spectrum. II. Sensitivity of tumors to fourteen antitumor chemicals. PMID- 4223041 TI - [Multidirectional effect mechanism of heparin]. PMID- 4223042 TI - [Dispensarization of children with dental and maxillary abnormalities]. PMID- 4223043 TI - The uncoupling of respiratory-chain phosphorylation by 4,5,6,7-tetrachloro-2 trifluoromethylbenzimidazole. AB - 1. 30mmum-4,5,6,7-Tetrachloro-2-trifluoromethylbenzimidazole (TTFB) uncouples respiratory-chain phosphorylation. The respiration rate of uncoupled mitochondria is significantly greater than the state 3 rate. Neither added orthophosphate nor ATP is required to sustain this rate. The oligomycin- and octylguanidine-induced inhibitions of respiration are relieved by uncoupling concentrations of TTFB. 2. Uncoupling concentrations of TTFB elicit a high adenosinetriphosphatase activity and inhibit the ATP-dependent succinate-linked reduction of NAD catalysed by submitochondrial particles from ox-heart mitochondria. 3. The action of TTFB is similar to that of 2,4-dinitrophenol. Evidence is presented which shows that it is the anionic forms of benzimidazoles and imidazoles, having the negative charge localized on the ring nitrogen atom, which are the effective uncoupling agents. PMID- 4223044 TI - The enzymic oxidation of thiols. PMID- 4223045 TI - [On the acid mucopolysaccharide content of bovine dental pulp]. PMID- 4223046 TI - [Experimental urinary tract infections especially in connection with fibrinolytic enzyme system. (Preliminary report)]. PMID- 4223047 TI - [Changes in the Danish invalidity pension regulations]. PMID- 4223048 TI - Pseudodisc--the problem of backache. PMID- 4223049 TI - ["Insufficientia vertebrae" today]. PMID- 4223050 TI - Effects of dinitrophenol and oligomycin on the coupling between anaerobic metabolism and anaerobic sodium transport by the isolated turtle bladder. AB - Dinitrophenol (1 x 10(-5)M) has been found to inhibit anaerobic sodium transport by the isolated urinary bladder of the fresh water turtle. Concurrently, anaerobic glycolysis was stimulated markedly. However, tissue ATP levels diminished only modestly, remaining at approximately 75% of values observed under anaerobic conditions without DNP. The utilization of glucose (from endogenous glycogen) corresponded closely to that predicted from the molar quantities of lactate formed. Thus the glycolytic pathway was completed in the presence of DNP and if ATP were synthesized normally during glycolysis, synthesis should have been increased. On the other hand, the decrease in Na transport should have decreased ATP utilization. Oligomycin did not block sodium transport either aerobically or anaerobically, but ATP concentrations did decrease. When anaerobic glycolysis was blocked by iodoacetate, pyruvate did not sustain sodium transport thus suggesting that no electron acceptors were available in the system. Two explanations are entertained for the anaerobic effect of DNP: (a) Stimulation by DNP of plasma membrane as well as mitochondrial ATPase activity; (b) inhibition of a high energy intermediate derived from glycolytic ATP or from glycolysis per se. The arguments relevant to each possibility are presented in the text. Although definitive resolution is not possible, we believe that the data favor the hypothesis that there was a high energy intermediate in the anaerobic system and that this intermediate, rather than ATP, served as the immediate source of energy for the sodium pump. PMID- 4223051 TI - Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids. PMID- 4223052 TI - The effect of long-term ethionine treatment on the activity of the serum properdin in rats. PMID- 4223053 TI - Studies on the alteration of species-specific resistance by ethionine-induced inhibition of protein metabolism. 3. Infection experiments in rats with Teschen disease virus. PMID- 4223054 TI - Ganglioside inhibition of blood group antibodies with special reference to blood group I. PMID- 4223055 TI - [On the formation of antibodies against human thrombocytes in rabbits following immunization with human unwashed erythrocytes]. PMID- 4223056 TI - [Typing of thrombocytic antigens with the aid of rabbit immune antithrombocytic sera]. PMID- 4223057 TI - [Animal experimental contribution on the problem of antibody formation following splenectomy]. PMID- 4223059 TI - [On demonstration of vaccinia virus in the blood of cutaneously inoculated rabbits]. PMID- 4223058 TI - [Studies with 3 agglutinating protein fractions from Phaseolous vulgaris and Vicia faba on their effect on erythrocytes of various animal species]. PMID- 4223060 TI - On measuring left ventricular volume. PMID- 4223061 TI - The allosteric nature of substrate inhibition of insect actomyosin ATPase in presence of magnesium. PMID- 4223062 TI - Cardiac performance in heart-lung preparations of rats with experimental cardiac hypertrophy. PMID- 4223063 TI - My aching back. PMID- 4223064 TI - Plasma enzymes that release kinins. PMID- 4223066 TI - Camping though handicapped. PMID- 4223065 TI - The haemophilic boy in school. PMID- 4223067 TI - Unbinding the homebound. PMID- 4223068 TI - An improved method for the determination of orthophosphate suitable for assay of adenosine triphosphatase activity. PMID- 4223069 TI - Influences of public health education. PMID- 4223070 TI - Controlled clinical trial of "Atromid" (androsterone with ethyl-p-chlorophenoxy isobutyrate) and "Persantin" (dipyridamole) in cases of myocardial infarction. PMID- 4223071 TI - Urological management of paraplegic patients. PMID- 4223072 TI - The protein nutritive quality of ikan bilis (Stolephorus spp.). PMID- 4223073 TI - A study of the haemolysin test in the identification of V. Cholerae biotype, El Tor. PMID- 4223074 TI - A study of the psychosomatic aspects of peptic ulcer. PMID- 4223075 TI - The life cycles of nematodes parasitic in man: an evolutionary sequence. PMID- 4223076 TI - [Allergic skin diseases]. PMID- 4223077 TI - [Action of some proteases on the biological properties of erythropoietin]. PMID- 4223078 TI - [Clinical psychology in dentistry]. PMID- 4223079 TI - [Studies on acid mucopolysaccharides in the urine. I. On urinary acid mucopolysaccharides in mongolism]. PMID- 4223080 TI - [The pedodontist and his relationships with other dental and medical specialists]. PMID- 4223081 TI - Evaluation of abdominal decompression during the first stage of labor. PMID- 4223082 TI - Acid mucopolysaccharides and cirrhosis of the liver. PMID- 4223083 TI - Studies on reticuloendothelial system and hematopoiesis. II. A study on the morphology and function of erythroblastic islet. PMID- 4223084 TI - The roentgenographic features of the KS mucopolysaccharidosis of Morquio (Morquio Brailsford's disease). PMID- 4223085 TI - Effects of diazoxide administration on plasma glucose, insulin, and lipids in Von Gierke's disease. PMID- 4223086 TI - [Determination of the mucopolysaccharide content of the aorta wall in experimental hyper- and hypothyroidism]. PMID- 4223087 TI - Rehabilitative nursing. PMID- 4223088 TI - Dressing activities for disabled persons. PMID- 4223089 TI - Federally financed dental care; could Ohio dentists meet the challenge? PMID- 4223090 TI - Prophylactic odontotomy: a review. PMID- 4223091 TI - [Histochemical demonstration of glycogen and mucopolysaccharides in the guinea pig brain following roentgen irradiation]. PMID- 4223092 TI - [Surgical treatment of some cases of rhinophyma]. PMID- 4223093 TI - The enteric surface coat on cat intestinal microvilli. AB - The enteric microvilli of the cat, bat, and man are coated with a conspicuous layer composed of fine filaments radiating from the outer dense leaflet of the plasma membrane. This surface coat is prominent on the absorptive cells but is not so thick on the goblet and undifferentiated crypt cells. In other species the surface coat is poorly developed or inconsistent, but all intestinal microvilli have traces of such a coating over the tips and sides of the microvilli. Tissues prepared by the ordinary sectioning techniques for electron microscopy usually reveal this component when stained with uranyl acetate followed by lead staining. The surface coat is intensely periodic acid-Schiff (PAS) positive and reacts with Alcian blue or Hale's colloidal iron stain for acid mucopolysaccharide. It is also stained by toluidine blue at low pH. Repeated washings or incubation with various chemical agents have failed to remove or markedly alter the appearance of the coating, but extruded cells undergoing autolysis lose their surface coats. The stability, consistent presence, and intimate association of the mucopolysaccharide coat suggest that it may be an integral part of the plasmalemma rather than an "extraneous coat." PMID- 4223094 TI - Antibacterial management of infection due to gram-negative bacilli. 3. Use of ampicillin, the cephalosporins, spectinomycin, and chemotherapy. PMID- 4223095 TI - Self-adaptive control and respiratory system. PMID- 4223096 TI - Nicotinamide mononucleotide pyrophosphorylase activity in ascites cell extracts. PMID- 4223097 TI - Incidence of disability in 1965. PMID- 4223098 TI - Congenital anomalies of the abdominal musculature and urogenital tract in a foal. PMID- 4223099 TI - Skin eruption in a patient receiving hemineurine. PMID- 4223100 TI - [On a hormone dependent inhibitor of proteolytic enzymes in male accessory sex glands and in sperm]. PMID- 4223101 TI - [Studies of the chemistry of the arterial wall. 8. Demonstration, purification and properties of hyaluronidase from the aorta of cattle]. PMID- 4223102 TI - Sulfhydryl groups involved in the active site of myosin A adenosine triphosphatase. I. Specific blocking of the SH group responsible for the inhibitory phase in "B phasic response" of the catalytic activity. PMID- 4223103 TI - [Current status of the problem of seborrhea of the scalp. (Review of the literature)]. PMID- 4223104 TI - [Experience with separate dispensary services for patients with urogenital trichomoniasis in Tarta]. PMID- 4223105 TI - Testimony of employer's doctor admissible in workmen's compensation case. PMID- 4223106 TI - [Peritoneoscopic confirmation of a cure in a case of tuberculous peritonitis]. PMID- 4223107 TI - Sequential experimentation and multivariate analysis in the evaluation of a treatment for postoperative intestinal symptoms. PMID- 4223108 TI - [Changes in parotid saliva under the influence of hydrocortisone]. PMID- 4223109 TI - A medical history of poison ivy (Rhus toxicodendron). PMID- 4223110 TI - [Dynamics of the enzymatic activity of myocardial myosin in compensatory cardiac hyperfunction]. PMID- 4223111 TI - [Effect of compensatory hyperfunction and hypertrophy of the heart on the content of vitamin B-1 and B-2 in the heart muscle and liver]. PMID- 4223112 TI - [On the "yellow finger-nail syndrome"]. PMID- 4223113 TI - Microscopic anatomy and histochemistry of glands in the external auditory meatus of the cat (Felis domesticus). PMID- 4223114 TI - [Surgical treatment of onychomycoses, leukonychias, recessive mycoses and mycotic paronychias combined with 1 per cent solution of alcoholic pentachlorophenol solution]. PMID- 4223115 TI - Thin-layer chromatography and the rapid identification of common acidic glycosaminoglycans. PMID- 4223116 TI - Obesity and heart failure. PMID- 4223117 TI - The interpretation of non-hyperbolic rate curves for two-substrate enzymes. A possible mechanism for phosphofructokinase. AB - 1. A theoretical appraisal of the alternative pathway mechanism for a two substrate enzyme shows that this mechanism is capable of giving rise to apparent substrate inhibition or substrate activation (Dalziel, 1958). It has now been shown that these phenomena may occur simultaneously in the following ways. With certain relationships between the kinetic parameters and the constant concentration of one substrate, A, the plot of initial rate, v, against the concentration of the other substrate, B, may show substrate ;activation' at low concentrations of B and substrate ;inhibition' at high concentrations of B. In other circumstances the plot of v against [B], with [A] constant, may be sigmoid (substrate activation), whereas the plot of v against [A], with [B] constant, may pass through a maximum (substrate inhibition). 2. Kinetic data for phosphofructokinase are of the latter type and it is suggested that the mechanism of this enzyme may involve a kinetically preferred pathway. It is emphasized that the phenomena of substrate inhibition and activation need not necessarily involve more than one binding site for each substrate on the enzyme molecule, nor more than one monomer per molecule. PMID- 4223118 TI - Legal aspects of industrial immunization programs. PMID- 4223119 TI - Referral to attorneys. PMID- 4223120 TI - [New method for the rapid isolation of nerve ending particles and the demonstration of Na-K adenosine triphosphatase activity]. PMID- 4223121 TI - Audiological assessment of a mongoloid population. PMID- 4223122 TI - Studies on progressive muscular dystrophy. I. Effects of adenosinetriphosphate and its related compounds on progressive muscular dystrophy. PMID- 4223123 TI - [Symposium on the significance of enzymes in the field of internal medicine. On ATP-ases]. PMID- 4223124 TI - Another cause of low back pain: lipomata in the sacroiliac region. PMID- 4223125 TI - Fate of injected dehydroisoandrosterone, testosterone, and dehydroiisoandrosterone sulfate in plasma in the human. PMID- 4223126 TI - Aryl and steroid sulfatase in the human ovary. PMID- 4223127 TI - The stabilizing effect of neutral salts on plasmin. PMID- 4223128 TI - [Mongolism]. PMID- 4223129 TI - A survey of Salmonella VI-phage types occurring in Federation of Malaya and Singapore. PMID- 4223130 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 35-1966. PMID- 4223131 TI - Pyogenic abdominal wall and psoas abscesses in children. PMID- 4223132 TI - [Activity of the Center for Educational Guidance of the commune of Carrara. Considerations on the necessity of conforming the scholastic equipment to the needs of the Center]. PMID- 4223133 TI - Benzoyl peroxide and sulfur: foundation for acne management. AB - One hundred and thirteen consecutive patients with acne were studied by qualified dermatologists during a trial of topical 10% benzoyl peroxide and 2%-5% sulfur cream. The results were considered "good" to "excellent" in both office and clinic situations. The method was remarkably free of undesirable side effects. The program has been adopted as a standard acne regimen at the dermatology clinic of the Royal Victoria Hospital, Montreal. PMID- 4223134 TI - Applicability of exfolative vaginal cytology in sexual hormonology. PMID- 4223135 TI - Changing concepts in obstetrics. PMID- 4223136 TI - Comparative study of intrauterine contraceptive devices--spiral, loop, and ring. PMID- 4223137 TI - Labor management with unlimited clean vaginal examinations; a review of 4,537 cases. PMID- 4223139 TI - Sex health for college students. PMID- 4223138 TI - Safety evaluation of an acid powder for routine vaginal cleansing. PMID- 4223140 TI - Myeloid leukemia C-1498 as a screen for cancer chemotherapeutic agents. PMID- 4223141 TI - [Contribution to the electrocardiographic diagnosis of biventricular hypertrophy]. PMID- 4223142 TI - Vectorcardiographic signs of biventricular hypertrophy. PMID- 4223143 TI - [We and the children]. PMID- 4223144 TI - [Light microscopic, histochemical and electron microscopic studies on albino rats during oral dosage of 2, 4 dinitrophenol]. PMID- 4223145 TI - [Studies on atherosclerosis, with reference to acid mucopolysaccharide. I]. PMID- 4223146 TI - [Studies on atherosclerosis, with reference to acid mucopolysaccharide. II]. PMID- 4223147 TI - [Experiences with a new fat-soluble pyridoxine derivative in sebostatic and seborrheic diseases]. PMID- 4223148 TI - Introduction: mucopolysaccharides. PMID- 4223149 TI - Very high molecular weight mucopolysaccharides and mucopolysaccharide-protein complexes--how far can we extrapolate? PMID- 4223150 TI - Fractionation of urinary biocolloids in children and adults by gel filtration. PMID- 4223151 TI - [Enzymes participating in mucopolysaccharide biosynthesis in granulation tissue]. PMID- 4223152 TI - [Enzymatic activity of actomyosin in the rat myometrium and sex steroid hormones]. PMID- 4223153 TI - A lymphocytosis-stimulating substance in Mongoloid plasma. PMID- 4223154 TI - Effect of a subcurative dose of TWSb on the levels of phosphate esters in Schistosoma mansoni. PMID- 4223155 TI - Adenosine-5'-sulfatopyrophosphate, an analogue of adenosine triphosphate. II. Interaction with myosin, actomyosin, and muscle fibers. PMID- 4223156 TI - Mechanism of the Crabtree effect in yeast grown with different glucose concentrations. PMID- 4223157 TI - Effect of alloxan on mitochondrial adenosinetriphosphatase activity and the ATP ADP exchange reaction. PMID- 4223158 TI - [Aloys Rudolph Vetter (1765-1806) and human helminthology]. PMID- 4223159 TI - [The excretion of nitrogen and phosphorus in a short-term deficient diet]. PMID- 4223161 TI - [Study on the innervation of tumors]. PMID- 4223160 TI - [Immunofluorescence in biological diagnosis. Its application to the serology of syphilis after adsorption of nonspecific antibodies by ultrasonicated Reiter treponema]. PMID- 4223162 TI - Effects of FUdR and thymidine on incorporation of deoxycytidine into DNA of Vicia faba. PMID- 4223165 TI - [Elaboration of the callus in diaphyseal fractures]. PMID- 4223164 TI - The early fate of autogenous grafts in the canine femoral vein. PMID- 4223163 TI - New, histological and biochemical, researches in experimentally induced arteriosclerosis. PMID- 4223166 TI - [Our experience with neck and head resection of the femur with angulation osteotomy]. PMID- 4223167 TI - [Critical study of the Eggers operation in cerebral motor weakness]. PMID- 4223168 TI - [The Milwaukee corset in the correction of structural scoliosis]. PMID- 4223169 TI - [Technic of arthrodesis of the shoulder by a posterior approach]. PMID- 4223170 TI - Oxidative phosphorylation accompanying oxidation of short-chain fatty acids by rat-liver mitochondria. AB - 1. The factors concerned in the estimation of P/O ratios when fatty acids are oxidized by rat-liver mitochondria have been assessed. 2. The oxidation of butyrate, hexanoate and octanoate is accompanied by ATP synthesis. At low concentrations of the fatty acids, P/O ratios approximately 2.5 are obtained. 3. Oxidative phosphorylation is uncoupled, respiratory control ratios are lowered and respiration is inhibited when the concentration of the fatty acid in the incubating medium is raised (to 5-10mm); octanoate is a more potent uncoupler than either hexanoate or butyrate. 4. Serum albumin and carnitine, either singly or in combination, protect the mitochondria from the effect exerted by the fatty acids. 5. The rate of oxidation of short-chain fatty acids in the presence of ADP is increased in the presence of carnitine. PMID- 4223172 TI - The effect of fasting on esterification of palmitate by rat liver in vitro. PMID- 4223173 TI - [Physical-chemical and enzymatic studies of calf heart myosin]. PMID- 4223171 TI - The action of neutral hypochlorite on epithelial mucopolysaccharides. AB - 1. The uptake of dilute neutral hypochlorite by epithelial mucopolysaccharides has been compared with that of proteins, polysaccharides, amino acids and sugars. The uptake has been shown to be related to the protein content of the mucopolysaccharides rather than their polysaccharide content. 2. The destruction of the components of epithelial mucopolysaccharides, certain sugars and polysaccharides after oxidation with dilute neutral hypochlorite at 0-4 degrees has been studied. Very little destruction of the sugar components occurred and in epithelial mucopolysaccharides the only amino acid destroyed specifically was arginine. 3. Oxidation of bovine submaxillary-gland mucoprotein and ovalbumin caused very little destruction of hexosamine and no detectable liberation of this residue as a free reducing group, indicating that the O-seryl galactosaminide and the N-acyl-glycosylamine linkages reported to be present in these compounds were relatively stable to hypochlorite. 4. Depolymerization of epithelial mucopolysaccharides by neutral hypochlorite has been studied by using gel filtration columns and compared with the depolymerization of polysaccharides and proteins under similar conditions. The polysaccharides examined were relatively resistant to oxidation whereas the proteins were extensively broken down. It is inferred that the extensive depolymerization of epithelial mucopolysaccharides by hypochlorite is related to their protein content rather than their polysaccharide content. 5. Fractionation of the products of oxidation of epithelial mucopolysaccharides by column procedures has revealed that the relative proportions of components in all fractions were similar to those in the original material. 6. Though this study does not provide unequivocal evidence from which the overall structure of this type of epithelial mucopolysaccharide may be deduced, the balance of probabilities now appears to favour a long polypeptide chain to which a large number of oligosaccharide side chains are attached via O seryl and O-threonyl glycosidic linkages. The results, however, are also consistent with an alternating sequence of short polysaccharide and polypeptide chains and further evidence is necessary before this structure can be ruled out. PMID- 4223174 TI - [On steroid conjugates in plasma. XV. In vivo biogenesis of C-19 steroid sulfatides]. PMID- 4223175 TI - Virulence and the biochemical characters of staphylococci. PMID- 4223176 TI - [Surgical treatment of rhinophyma. (Apropos of 50 operated cases)]. PMID- 4223177 TI - On the pathomorphology of osteomyelosclerosis. PMID- 4223178 TI - Histochemistry of lipid metabolism in the liver of rabbits treated with chlortetracycline (CTC). PMID- 4223180 TI - The spread of non-tuberculous pulmonary diseases in Bulgaria. PMID- 4223179 TI - Susceptibility of tubercle myobacteria to antibacterial drugs and its importance for the clinical course of tuberculosis. PMID- 4223181 TI - [New concepts in the treatment of blood enzyme disorders]. PMID- 4223182 TI - The environment: its role in surgical infections. PMID- 4223183 TI - [Studies on the frequency of cerebral fat embolism following injury with variously long survival time]. PMID- 4223184 TI - [Incomplete transverse syndrome in the lower cervical cord following traumatic thrombosis of the subclavian artery]. PMID- 4223185 TI - [Brain and meninges in peripheral electrical current flow]. PMID- 4223186 TI - [On evaluation of epilepsy following closed brain injury]. PMID- 4223187 TI - [Subjective complaints in noise-deafness . (Studies on 500 workers in noisy environment. I.)]. PMID- 4223188 TI - [Penetrating wood splinter injury of the lung, a remarkable artifact]. PMID- 4223189 TI - [Onychomycosis and other dermatomycoses caused by Microsporum gypseum in Hungary]. PMID- 4223190 TI - Arteriography: an aid in the diagnosis of vascular disease. PMID- 4223192 TI - Progress in earlier recognition of breast cancer. PMID- 4223191 TI - Pregnancy and delivery following bilateral ureteral transplant to the bowl for exstrophy of the bladder. Report of a case. PMID- 4223193 TI - Current acid-fast bacilli in Douglas County. PMID- 4223194 TI - Neurologic manifestations of hyperpyrexia. PMID- 4223195 TI - [II. Eruption disturbing influences]. PMID- 4223196 TI - [Clinical experiences on the normolipemizing effects of a new pharmaceutical preparation]. PMID- 4223197 TI - Voluntary service in child health and child care. PMID- 4223198 TI - [Studies on staphylococci in swine]. PMID- 4223200 TI - Facilities for the blind in Singapore. PMID- 4223199 TI - Intracellular autogenetic effects of muscular contration on extensor motoneurones. The silent period. AB - 1. Intracellular records have been taken from cat motoneurones belonging to gastrocnemius and soleus or to popliteal synergists during contractions of gastrocnemius and soleus, acting separately or jointly. Such contractions were elicited by brief tetani or single shocks to the peripheral end of the cut ventral roots L7 or S1.2. Hyperpolarization of the motoneurone accompanies rise of tension in contraction. The amount of it increases when at constant extension the contraction of the muscle is increased by increasing stimulus strength, as well as when it is increased by augmenting extension at constant stimulus strength. It is therefore tension-sensitive.3. The duration of the hyperpolarization induced in this manner reflects the duration of the contraction itself, being considerably longer in the slow soleus than in the faster gastrocnemius. It is often preceded by a brief wavelet of depolarization ascribed to the so-called back-response.4. Early in relaxation there occurs a transient ;hump' of membrane depolarization. This corresponds to the moment characterized by phasic bursts from the spindle primaries. The ;hump' terminates hyperpolarization.5. When the cell is stimulated by injected current to maintained repetitive firing, the ;silent period' in contraction begins with the phase of hyperpolarization and ends with the hump of depolarization as described above.6. Later during relaxation, delayed inhibition, may or may not follow often accompanied by hyperpolarizing activation noise and sometimes also visible as an extension of the silent period of a firing cell. There is, however, no marked hyperpolarization of the motoneurone in delayed inhibition.7. In the Discussion the events described above are related to previous studies employing monosynaptic testing or electromyography for the analysis of the variations of excitability caused in extensor motoneurones by autogenetic contractions as well as to known properties of stretch receptors. PMID- 4223201 TI - [Studies on methemoglobin formation after phenacetin administration in cats of various ages]. PMID- 4223202 TI - [Changes in the serotonin and histamine content of blood platelets due to the effect of local anesthetics]. PMID- 4223203 TI - [On the mechanism of 6-aminonicotinamide hyperglycemia]. PMID- 4223204 TI - [Catecholamine and ATP content of adrenal glands after administration of 6 aminonicotinamide]. PMID- 4223206 TI - [Participation of insulin in diazoxide hyperglycemia]. PMID- 4223205 TI - [Biochemical bases of diazoxide hyperglycemia]. PMID- 4223208 TI - [The effect of hydrochlorthiazide on the blood sugar-increasing action of diazoxide]. PMID- 4223207 TI - [Mechanism of increased glycogenolytic effect of diazoxide in potassium deficiency]. PMID- 4223209 TI - [Comparative studies of mucopolysaccharide composition of the coronary arteries and the aorta]. PMID- 4223210 TI - [Mucopolysaccharides of the vascular wall and their role in the pathogenesis of arteriosclerosis]. PMID- 4223211 TI - Systemic eczematous "contact-type" dermatitis medicamentosa. PMID- 4223213 TI - Copper poisoning in the snail Helix pomatia and its effect on mucous secretion. PMID- 4223212 TI - Dichlorophene allergy. PMID- 4223214 TI - The anterior salivary gland of the octopus (Octopus vulgaris) and its mucous secretion. PMID- 4223215 TI - The presence of mucopolysaccharides in the hepatopancreas of the isopod, Armadillidium vulgare. PMID- 4223216 TI - Inhibition of proteolytic enzymes by beta-lipoprotein. PMID- 4223218 TI - Interagency coordination. A basic need in serving handicapped children. PMID- 4223217 TI - Effects of MgEDTA on the mucopolysaccharide metabolism in the atherosclerotic aorta. PMID- 4223219 TI - [Allergic occupational dermatoses in Austria]. PMID- 4223220 TI - [Clinical experiences with a Valium treatment of the cervical syndrome and the lumbar radicular irritation syndrome in women]. PMID- 4223221 TI - [Zoobiocenological studies on the steppes of Kazakhstan and some general problems of biocenology]. PMID- 4223222 TI - Activation and inhibition of myosin B adenosine triphosphatase by mg++ and ca++ at low concentration of KC1. PMID- 4223223 TI - Optical rotatory dispersion and enzymic studies on the tryptic digestion of rabbit skeletal and cardiac myosins and their macromolecular fragments. PMID- 4223224 TI - Bound adenosine diphosphate and adenosine triphosphate in resting and contracting muscle. PMID- 4223225 TI - [On some contemporary problems of Down's disease]. PMID- 4223226 TI - [Diagnosis of spontaneous generalized hyperfibrinolyses]. PMID- 4223227 TI - Histochemical investigations on the behaviour of some enzymes in liver cells of the mouse under the influence of oestrogens. I. Alkaline phosphatase (ALP-ase), adenosinetriphosphatase (ATP-ase), acid phosphatase (AP-ase). PMID- 4223228 TI - Repair of defects after partial resection of the abdominal wall. PMID- 4223229 TI - [Advances in clinical electrocardiography. Hypertrophies of the left ventricle and of the right ventricle]. PMID- 4223230 TI - [Etiological survey of 150 cases of medicamentous toxicoderma. Value of Shelley's test]. PMID- 4223231 TI - [Contact allergy to clophenoxyde]. PMID- 4223232 TI - [Epicutaneous tests and occupational dermatoses. Histological study]. PMID- 4223234 TI - [Gigantic left auricle]. PMID- 4223233 TI - [Contribution of circulating cholesterol and cholesterol sulfate to the biosynthesis of testicular and adrenocortical hormones]. PMID- 4223235 TI - [Medical therapy and surgical therapy of radiodermatitis]. PMID- 4223236 TI - [Effectiveness of malachite green solution in the treatment of carp ichthyophthiriosis]. PMID- 4223237 TI - [Vibrio abortion in cattle in Kazakhstan]. PMID- 4223239 TI - Adenosine triphosphatase activity of adrenal medulla catecholamine granules. PMID- 4223238 TI - Psychological correlates of the MFS rehabilitation rating scale. PMID- 4223240 TI - Accumulation of Ca2+ and Sr2+ by rat-liver mitochondria: preferential loss of the adenosine triphosphate-dependent mechanism for Sr2+ accumulation. PMID- 4223241 TI - The right ventricle and pulmonary vascular obstruction in bronchitis with emphysema. PMID- 4223243 TI - [Trends in pedodontics]. PMID- 4223242 TI - The electrocardiogram in chronic bronchitis and emphysema. PMID- 4223244 TI - Cytochemical observations on chick liver cell cultures infected with Trichomonas vaginalis. 1. Nucleic acids, polysaccharides, lipids, and proteins. PMID- 4223245 TI - Organ culture studies of hormone secretion in endocrine glands of fetal guinea pigs. 1. Androgenic secretion as demonstrated by a bioindicator method. PMID- 4223246 TI - Organ culture studies of hormone secretion in endocrine glands of fetal guinea pigs. II. Secretion of androgenic hormone in adrenals and testes during early stages of development. PMID- 4223248 TI - [Bioloical bionics]. PMID- 4223247 TI - [The imperatives of night vision in the Navy]. PMID- 4223249 TI - [Practical medical problems of the 1st cruise around the world by the helicopter carrier, Jeanne-d'Arc]. PMID- 4223250 TI - [Binocular vision and the occupational valve of spotter personnel]. PMID- 4223251 TI - [On the storage of mucopolysaccharide-like substances in the brain in generalized glycogenosis (type II)]. PMID- 4223252 TI - [Histochemical characteristics of the mucopolysaccharides in the ground substance of the stroma of laryngeal epitheliomas]. PMID- 4223253 TI - The occurrence of relaxing granules in the muscle of the locust, Locust migratoria. PMID- 4223254 TI - Anticoccidial activity of nicotinamide antagonists. PMID- 4223255 TI - [Inguinal region in the human fetus]. PMID- 4223257 TI - [Large, temporarily osteoclastic skull trepanation as a palliative intervention in posttraumatic intracranial pressure increase]. PMID- 4223256 TI - [History of a "tendinitis"]. PMID- 4223258 TI - [Infantile radius fractures]. PMID- 4223259 TI - [Results of conservative treatment of 217 lower leg shaft fractures]. PMID- 4223260 TI - [Gemmangioma following trauma. A case report on the problem of traumatic origin of tumors]. PMID- 4223261 TI - [On the luxation in Lisfranc's joint]. PMID- 4223262 TI - [Non-recognition of a lymphoid cyst as caused by an accident]. PMID- 4223263 TI - [Perforation of a foreign body from the sigmoid into the rectus abdominis muscle]. PMID- 4223264 TI - The occurrence and mechanism of P-wave inversion in lead I in right atrial overloading. Report of two cases. PMID- 4223265 TI - Cardiomegaly in myxedema. Report of a case and review of the literature. PMID- 4223266 TI - Infant and child mortality in Burma by ethnic group. PMID- 4223267 TI - Correlative study between electrocardiographic findings and ventricular wall thickness based on cardio-synchronous angiocardiography. I. Comparison of angiocardiographic and postmortem thickness of ventricular wall in normal dogs. PMID- 4223268 TI - Norepinephrine metabolism in hypertrophied rat hearts. PMID- 4223269 TI - Effect of carcinolipin on the adenosine triphosphatase activity of isolated cellular fractions. PMID- 4223270 TI - Hormonal regulation of cardiac muscle citrate. PMID- 4223271 TI - Delineating the possible for the multi-handicapped child with visual impairment. PMID- 4223272 TI - [Nature of the dynamics of arterial pressure in mechanics and agricultural workers]. PMID- 4223273 TI - [Investigations on the etiology of contact eczema. I. Changes in the frequency of certain contact eczema allergens during the last decennium]. PMID- 4223274 TI - [Chemical sensitizations in the oil industry]. PMID- 4223275 TI - [Occupational aspects of porphyria cutanea tarda and the results of its treatment with anabolic steroid hormones]. PMID- 4223276 TI - [30,000 East marks accident compensation for the simulation of an elbow joint stiffening]. PMID- 4223277 TI - [Significance of inguinal pain for the diagnosis of disk sciatica]. PMID- 4223278 TI - [Can we classify occupational and drug-induced acne as belonging to the varieties of acne vulgaris?]. PMID- 4223279 TI - [n the problem of the cause of non-specific positive results of the 2-phase serum trypsin test]. PMID- 4223280 TI - [Experiences with serodiagnosis of human brucellosis with special reference to the incidence and demonstration procedure of incomplete antibodies]. PMID- 4223281 TI - [On the production of cerebroside antibodies following intradermal injection of cerebroside-protein adjuvant emulsions]. PMID- 4223282 TI - Studies on vaccination against cholera. 3. Immune response in man. PMID- 4223283 TI - [Demonstration of parasite-specific antibodies in fish blood by means of the agar gel precipitation test]. PMID- 4223284 TI - [On experimental amyloidosis in thymectomized mice]. PMID- 4223285 TI - [Sutureless test skin graft with a new tissue glue]. PMID- 4223286 TI - [The behavior of homologous and heterologous complement-fixing antibodies against poliomyelitis after oral vaccination with Sabin's live vaccine]. PMID- 4223287 TI - [Further studies on bovine neuraminic acid-containing mucoids]. PMID- 4223288 TI - [Hematoma of the rectus abdominis muscle in pregnancy]. PMID- 4223289 TI - [Complete atrioventricular block and cardiomegaly in a normotensive acromegalic patient]. PMID- 4223290 TI - [Steroid foam for local therapy of acne and other skin diseases]. PMID- 4223291 TI - [Cytochemistry of hypoplastic hemopathies]. PMID- 4223292 TI - [Neurology of cor pulmonale]. PMID- 4223293 TI - [Metastatic ovarian carcinomas of extragenital origin]. PMID- 4223294 TI - [Histochemical studies in placentas expelled after intravenous oxytocin infusion]. PMID- 4223295 TI - Heart size in pregnancy. PMID- 4223297 TI - [Studies on fibrinolysin in the field of obstetrics and gynecology]. PMID- 4223298 TI - Mycologic testing of soil samples from populated areas with endemic nephropathy. PMID- 4223299 TI - [Reactive epilepsy and homocide. 2. Homicide in short circuit]. PMID- 4223296 TI - [Influence of gonadectomy, testosterone or stilbestrol administration upon the excretory activity of seminal vesicles of rats]. PMID- 4223300 TI - On some metabolic and functional changes of the heart muscle in experimental myocarditis. PMID- 4223301 TI - Inquiries into the protein composition of the heart muscle in experimental myocarditis of dogs. PMID- 4223302 TI - Intraparenchymal distribution of the blood vessels of the thyroid gland. PMID- 4223303 TI - Early results of antibacterial treatment of newly traced consumptive patients. PMID- 4223304 TI - [Hematological and histological studies on some forms of generalized exfoliative erythrodermas]. PMID- 4223305 TI - [Role of the tick Demodex folliculorum hominis in human skin pathology]. PMID- 4223306 TI - [Use of a protective silicone cream in preventing dermatitis]. PMID- 4223307 TI - ["Myodegeneratio cordis" and findings in section material]. PMID- 4223309 TI - The use of mathematical model in the study of the properties of the full-surface electrocardiogram. I: Scher generators in a homogeneous torso. II: "Enlarged heart" potentials. PMID- 4223308 TI - [Spontaneous rupture of the aorta with special reference to idiopathic cystic aortic medionecrosis (Gsell-Erdheim disease)]. PMID- 4223310 TI - [Activity of the Center for Educational Guidance of the commune of Carrara. Considerations on the necessity of conforming the scholastic equipment to the needs of the Center]. PMID- 4223311 TI - Degradation of mucopolysaccharides by hepatic lysosomes. PMID- 4223312 TI - Inhibition by ergotamine and ergobasinine of Ca2+ uptake from the sarcotubular system. PMID- 4223313 TI - Gas-liquid chromatographic separation of C19 and C21 human urinary steroids by a new procedure. PMID- 4223314 TI - O-t-c anti-acne aids. PMID- 4223315 TI - The thymus and the tolerance function. PMID- 4223316 TI - [Current aspect of immunity in diseases due to Plasmodium]. PMID- 4223317 TI - Changes in biochemical properties of isolated human skeletal myofibrils with age and in Myasthenia gravis. PMID- 4223318 TI - Studies on erythrocyte glycolysis. II. Free energy changes and rate limitings steps in erythrocyte glycolysis. PMID- 4223319 TI - Studies on erythrocyte glycolysis. 3. The effects of active cation transport, pH and inorganic phosphate concentration on erythrocyte glycolysis. PMID- 4223320 TI - Superprecipitation of actomyosin reconstructed with F-actin and NEM-modified myosin. PMID- 4223321 TI - [Enzymologic studies in actomyosin of the uterine muscle in pregnant animals]. PMID- 4223322 TI - [Biochemical studies in the connective tissue of the pregnant uterine cervix with special reference to the analysis of acetic acid-soluble substance and urinary acid mucopolysaccharide]. PMID- 4223324 TI - Two-year pedodontic internship residency program is approved. PMID- 4223323 TI - [Symposium on the significance of enzymes in the field of internal medicine. (5). Significance of ATP-ase in cardiovascular diseases, with special reference to hypertensive diseases]. PMID- 4223325 TI - Dentistry and the handicapped child. PMID- 4223326 TI - Pedodontics at Harvard. PMID- 4223327 TI - Dental plan for children urged by professor. PMID- 4223328 TI - Prosthetic service for pre school children. PMID- 4223330 TI - A Head Start to where? PMID- 4223329 TI - The forgotten 3 per cent in the dental office--care of the mentally retarded. PMID- 4223331 TI - Camping with the chronic sick. PMID- 4223332 TI - [Experiences in the prosthetic care of a case of anodontia]. PMID- 4223333 TI - [Basic problems of psychology of the child]. PMID- 4223334 TI - [Basic problems of psychology of the child. (II)]. PMID- 4223335 TI - Morphological and histochemical studies of partially and totally deafferented spinal cord segments. PMID- 4223336 TI - [On the technic of peritoneoscopy]. PMID- 4223337 TI - [Cardiac enlargement and adjustment to exertion]. PMID- 4223339 TI - [Results of a cytogenetic and clinical study of 312 mongoloids. Significance of translocations and mosaicisms]. PMID- 4223340 TI - [Study of regression of the signs of left atrial overload in the electrocardiograms of patients with pure mitral stenosis, after open heart surgery]. PMID- 4223342 TI - [On the technic of peritoneoscopy]. PMID- 4223341 TI - [Electron microscopic demonstration of mitochondrial adenosine triphosphatase activity in animal tissues]. PMID- 4223343 TI - "Fear and anxiety in the dental chair". PMID- 4223344 TI - Water fluoridation--its effect on pedodontics. PMID- 4223345 TI - A dental care plan for Michigan children. PMID- 4223346 TI - PRESCAD--what is it? PMID- 4223347 TI - [On the therapy of luxation of the jaw in infants]. PMID- 4223348 TI - [The pedestal control method]. PMID- 4223349 TI - [Orthocryl--Polyclav--FKO-Fixator]. PMID- 4223350 TI - [The acrylic resin fused crown]. PMID- 4223352 TI - [Greater precision in castings of high melting metals through the Multi-Vest-Team of Ransom & Randolph]. PMID- 4223351 TI - [On experiences with the new denture retainers (saddle) for partial dentures]. PMID- 4223353 TI - [Isodrome-method for pin-lay "splints"]. PMID- 4223354 TI - [Static fusimotor fibers and dynamic fusimotor fibers in the rabbit]. PMID- 4223355 TI - The periodic synthesis of thymidine kinase in mouse fibroblasts. PMID- 4223356 TI - Further observations on the physiology and pharmacology of elasmobranch ventricular fluid. PMID- 4223357 TI - Studies on sodium-potassium-activated adenosinetriphosphatase. XV. The rectal gland of the elasmobranchs. PMID- 4223358 TI - [Studies of the corneal metabolism by a radioactive isotope. 1. Incorporation of 35S-sulfate into the mucopolysaccharide of rabbit cornea under various fundamental conditions]. PMID- 4223359 TI - [Local curarization by means of ionophoresis in the physiotherapy treatment of lumbalgias due to exercise and of painful muscular contractures]. PMID- 4223361 TI - Key figures in legislation for the handicapped. PMID- 4223362 TI - Abnormal response to anaesthesia in a case of Huntington's chorea. PMID- 4223360 TI - [On the characterization of heterozygotes of the phages T4]. PMID- 4223363 TI - Mongolism, leukemia and sex chromatin anomalies. PMID- 4223364 TI - [Dispensary service to one-eyed patients after injuries in the Moldavian SSR]. PMID- 4223365 TI - The fibrinolytic enzyme system in physiological pregnancies at term and during labour. PMID- 4223366 TI - Studies on hyaine membrane disease.3. Thrapeutic trial of urokinase-activated huma plasmin. PMID- 4223367 TI - Angiocardiographic determination of the size of the left ventricle in congenital heart disease. PMID- 4223368 TI - Painless chronic dissecting aneurysm of the aorta. Report of a case. PMID- 4223369 TI - The adenosine diphosphate--adenosine triposphate-excange reaction of cerebral microsomes and its relation to he sodium ion-stimulatd adenosine-triphosphatase reaction. AB - Microsomes from guinea-pig cerebral cortex contain a system capable of exchanging ADP with ATP at rates of about 20mumoles/mg. of protein/hr. The ADP-ATP-exchange reaction requires Mg(2+) for activity. The reaction is not stimulated by Na(+) or K(+) and is not inhibited by ouabain, in contrast with the Na(+)-plus-K(+) stimulated adenosine triphosphatase. The pH optimum also differs from that of the adenosine triphosphatase. The ADP-ATP-exchange reaction is stimulated two- to three-fold by non-ionic, anionic and cationic detergents, even when these agents are inhibiting the adenosine-triphosphatase reaction. This reaction may represent a component of the Na(+)-plus-K(+)-stimulated adenosine-triphosphatase reaction but is more likely to be due to other enzyme systems present in microsomal subfractions. PMID- 4223370 TI - The pre-steady state of the myosin--adenosine triphosphate system. IV. Liberation of ADP from the myosin--ATP system and effects of modifiers on the phosphorylation of myosin. PMID- 4223371 TI - Calcium-dependent granular adenosinetriphosphatase from glycerinated myofibrils. PMID- 4223372 TI - Role of ADP bound to F-actin in superprecipitation and enzymatic activity of actomyosin. PMID- 4223373 TI - [Problems with employment of heart and circulatory patients in agriculture]. PMID- 4223375 TI - An antithrombin (maculatin) and a plasminogen activator extractable from the blood-sucking hemipteran, Eutriatoma maculatus. PMID- 4223374 TI - Inhibition of gastric secretion by fractionated lymph. Elaboration of gastrone like substance during digestive phases in dogs. PMID- 4223376 TI - Studies of erythrocyte spicule formation in haemolytic anaemia. PMID- 4223377 TI - Endotoxin shock in the New Zealand white rabbit. An evaluation of fibrinolysin therapy. PMID- 4223378 TI - [The vectorcardiogram in mitral stenosis prior and subsequent to commissurotomy]. PMID- 4223379 TI - [On hepatic involvement in atherosclerosis]. PMID- 4223380 TI - [The occurrence of atherosclerosis among the inhabitants of the city of Sofia]. PMID- 4223381 TI - [On hepatic involvement in acquired toxoplasmosis]. PMID- 4223382 TI - [Haemoptysis and pulmonary haemorrhages in a clinic for pulmonary tuberculosis]. PMID- 4223383 TI - [Forms of tuberculosis and their course in some cases of altered reactivity of the organism]. PMID- 4223384 TI - [Staphylococci as agents of hospital infections]. PMID- 4223385 TI - On some functional and histochemical changes in myocarditis of rabbits induced by streptolysine and A-group streptococci. PMID- 4223386 TI - [On the alterations of the aortic wall in rheumatism of infancy]. PMID- 4223387 TI - [On the influence of extramedullary haemopoiesis on the vessel wall in leukemia. (Histological studies)]. PMID- 4223388 TI - [Studies of stratification of food in the stomach of people with a decreased gastric tonus]. PMID- 4223389 TI - [Metabolism of the myocardium]. PMID- 4223390 TI - [Histochemical investigations of kidneys of guinea pigs following chronic noise influence]. PMID- 4223391 TI - [On the relationship between the size of ganglion cells and the extension of their innervation zone]. PMID- 4223392 TI - Meiosis in trisomic Down's syndrome. PMID- 4223393 TI - [Chromosome anomalies caused by surplus (trisomies) and age of the mother]. PMID- 4223394 TI - Hygienic and experimental studies of the conditions of work and occupational morbidity in electric and gas welders. PMID- 4223395 TI - [Biological half-life periods of C21-steroids in guinea pigs]. PMID- 4223396 TI - Intrapericardial fat pads and anomalous development of the septum transversum as a cause of pseudocardiomegaly. PMID- 4223397 TI - Luetic aneurysms of the aortic valve, sinus of Valsalva, and aorta. PMID- 4223398 TI - Experimental retinal vein occlusion and treatment with fibrinolysin. PMID- 4223399 TI - Studies in sickle cell anemia. XXVII. Complications in infants and children in the United States. PMID- 4223400 TI - Rehabilitation of the injured worker. PMID- 4223402 TI - Effect of hypertrophy on myocardial distensibility. PMID- 4223401 TI - [Skin manifestations of drug side effects in the patient material of 1 year at the dermatologic clinic of the University of Debrecen]. PMID- 4223403 TI - Chromosomes of "mongoloid" hamsters. PMID- 4223404 TI - Psychosomatic aspects of acne: a controlled study. PMID- 4223405 TI - Estimation of dehydroepiandrosterone sulfate in human serum by gas-liquid chromatography. PMID- 4223406 TI - Estimation of trypsin in presence of plasmin and their separation by gel filtration. PMID- 4223407 TI - Effects of zinc on adenosine triphosphatase activity and superprecipitation of actomyosin from skeletal muscle of rabbit. PMID- 4223409 TI - Effects of preparations of heparin and heparitin sulfate on fibrinolysis. PMID- 4223408 TI - Stimulation of Na+ and K+ dependent adenosine triphosphatase by ouabain. PMID- 4223410 TI - Immunology and cancer. PMID- 4223411 TI - Psychologic aspect of ulcerative colitis in children. PMID- 4223413 TI - Recent advances in treatment of the eye. PMID- 4223412 TI - Metabolic and statural response to human growth hormone in juvenile Cushing's syndrome with dwarfism. PMID- 4223414 TI - [Study on eczema caused by pyrins, with special reference to its allergic function]. PMID- 4223415 TI - Controlled relaxation. I. Quantitation of electromyogram with abdominal relaxation. PMID- 4223416 TI - The "butterfly" eruption. PMID- 4223417 TI - Dilatation of the heart. PMID- 4223419 TI - [Principal results of a study of epidemiology of Q fever in Kazakhstan]. PMID- 4223418 TI - [On the lyophilization of type-specific staphylococcal phages]. PMID- 4223420 TI - Leftward shift of the terminal P forces in the ECG associated with left atrial enlargement. PMID- 4223421 TI - Clinical pathologic conference. PMID- 4223422 TI - [The binding of phenothiazine derivatives with biogenic polyelectrolytes as a pattern for the elucidation of some aspects of their pharmacodynamics. I. Model investigation of the binding of phenothiazine derivatives with biogenic polyelectrolytes through displacement of metachromatically bound dyes]. PMID- 4223423 TI - The action of ketonic prostaglandins on the guinea-pig myometrium. AB - 1. Prostaglandin E(1) or E(2) has two clearly distinguishable effects on the guinea-pig myometrium in vitro.2. The first of these, the ;direct' effect, is manifested by contraction accompanied by spiking, is readily modified by changes in the concentrations of Mg(2+), Ca(2+) and K(+) in the suspension medium, and does not long outlast the presence of the prostaglandin in the organ-bath. In this respect it resembles the responses to other stimulants.3. The second effect is manifested by ;enhancement' of the responses to non-specific stimulation, whether this be by chemical or electrical means. Enhancement may be demonstrated for up to 20-80 min after the PGE(1) or PGE(2) has been washed out of the organ bath, and during this time the myometrium shows no consistent changes in electrical activity or in resting mechanical tension that may be associated with the enhancement effect. Enhancement following PGEs is not readily affected by moderate changes in the Mg(2+), Ca(2+) or K(+) concentrations of the suspension medium, and in all these respects it differs markedly from the effects of other stimulants.4. K(+)-depolarized myometrial preparations show feeble direct responses to PGEs, like those to other stimulants. They also show post-PGE enhancement of the responses to other stimulants, but not of the responses to electric field stimulation.5. The empirical method used for measuring the enhancement effect is examined critically.6. The possible mechanisms of the direct and enhancement effects are discussed. It is postulated that they involve actions at two different sites, which may be on two different types of cell but are more likely to co-exist on the same cells. The direct effect is postulated to result from depolarization at the exposed cell membrane, whereas enhancement may result from facilitation of excitation-contraction coupling. PMID- 4223424 TI - The reflex response to sinusoidal stretching of soleus in the decerebrate cat. AB - 1. Soleus muscle in the decerebrate cat was stretched sinusoidally through various distances, at various frequencies while tension and e.m.g. activity were recorded.2. Two patterns of stretch reflex activity were seen. In one, slow stretching led to a large increase in tension, whereas in the other tension increased little during slow stretching, but rose steeply during a more rapid stretch. Intermediate states were also seen.3. Both these reflex patterns were abolished when the fusimotor fibres were blocked with Xylocaine.4. At low frequencies of stretching the e.m.g. activity was greatest at peak muscle length; at higher frequencies the greatest activity was found during lengthening. This angular advance of e.m.g. activity on length was greatest at 3.3-5 c/s. At the higher frequencies the e.m.g. activity was less in advance of muscle length.5. Angular advance of e.m.g. activity was greatest in the preparations that were also the most sensitive to slow stretching.6. Muscle contraction follows an electrical stimulus with a small delay. The delay between the end of stimulation and the end of muscle relaxation is longer, and may exceed 200 msec in cat soleus.7. The timing of the reflex tension during sinusoidal stretching depended on how far the angular advance of the e.m.g. combined with the damping properties of muscle offset the time delays in the reflex pathway.8. Changes in muscle tension generally preceded changes in muscle length. When, however, stretch amplitudes of 1 mm (peak to peak) were used, a phase delay of tension was sometimes seen. This only occurred in preparations that also showed little sensitivity to slow stretching.9. Phase delay of tension was usually found with frequencies of approximately 6-8 c/s, and this corresponds to the clonus frequency for soleus.10. The mechanisms of the two types of reflex behaviour, and the damping properties of the system are discussed. PMID- 4223425 TI - Organization of neurones in the cat cerebral cortex that are influenced from group I muscle afferents. AB - 1. Neurones in the Group I projection area of the first sensori-motor cortex were investigated with extra- and intracellular technique.2. The majority of the neurones influenced by volleys in Group I afferents of contralateral forelimb nerves received exclusively excitation, but some received exclusively inhibition, and some mixed excitation and inhibition.3. The Group I influenced cells were usually found 500-1500 mu beneath the cortical surface.4. The EPSPs and IPSPs evoked from Group I afferents had a steep rising phase and a slow, approximately exponential decay. The duration was sometimes more than 50 msec. The EPSP evoked by a maximal Group I volley was often formed by a small number of large unitary EPSPs.5. Latency measurements indicate that the majority of the Group I activated neurones were monosynaptically excited from the thalamic fibres, and hence constitute the fourth-order neurones in the Group I projection system. The latencies of the IPSPs suggest a disynaptic linkage with thalamic fibres. Hence, the exclusively inhibited cells would constitute fifth-order neurones. It is suggested that most or all of the fourth-order neurones are inhibitory.6. The convergence of excitation and/or inhibition to individual cells was usually extensive and included effects not only from muscle groups working at different joints but also effects from antagonistic groups at the same joint. In addition cutaneous afferents contributed synaptic actions which had a longer latency than the synaptic actions from Group I afferents.7. The neurones influenced from Group I afferents were not antidromically activated on stimulation of the pyramidal tract. PMID- 4223426 TI - Topical corticosteroids for skin disorders. PMID- 4223427 TI - [Expert testimony in awarding of pensions. I]. PMID- 4223428 TI - [Laparoscopy in the diagnosis of stomach cancer]. PMID- 4223429 TI - [Culdoopy and laparoscopy in the diagnosis of ovarian tumors]. PMID- 4223430 TI - [Friedrich Pauwels at the completion of his 80th year of life on May 23, 1965]. PMID- 4223431 TI - [On the problem of the genetically or metabolically caused development of Recklinghausen's neurofibromatosis]. PMID- 4223432 TI - [Can experimental osteolathyrism be considered as a pattern for human skeletal deformities?]. PMID- 4223433 TI - [Biocristallographic studies on the structural changes in degenerated human tendons]. PMID- 4223434 TI - [On the development and abdominal treatment of so-called infant's scoliosis and hip dysplasia in the scope of Siebener's syndrome]. PMID- 4223435 TI - [A contribution to the treatment of the torn lateral knee ligament using articular active movement]. PMID- 4223436 TI - [The fibula-pro-tibia operation]. PMID- 4223438 TI - [The measurement of the humeral torsion with roentgen photographs in the 3rd plane and the description of thereby observed changes to the tubercle]. PMID- 4223437 TI - [Supracondylar femoral osteotomy in hemophilia A]. PMID- 4223439 TI - [A rare case of hereditary brachybasophalangy]. PMID- 4223440 TI - [Familial synostosis of metacarpi IV and V]. PMID- 4223441 TI - [A contribution to the problem of secondary disorders of the hand skeleton differentiation in primary malformation of the soft part blastema]. PMID- 4223442 TI - [Osteo-onycho dysplasia]. PMID- 4223443 TI - [Calcinosis cutis circumscripta]. PMID- 4223444 TI - [Osteo-onycho dysplasia (Turner's syndrome, nail-patella syndrome)]. PMID- 4223445 TI - [The return to normal of muscle capacity after the stopping of isometric training]. PMID- 4223447 TI - [On the problem of the intertrochanteric so-called motor osteotomy in coxarthrosis]. PMID- 4223446 TI - [Spontaneous patellar dislocation]. PMID- 4223448 TI - [On the development of Perthes' capitulum]. PMID- 4223449 TI - Congenital heart disease and pheochromocytoma. PMID- 4223450 TI - Paternal transmission of a D/G translocation of Down's syndrome. PMID- 4223451 TI - Anodontia in mongolism. PMID- 4223452 TI - Change in platelet antiplasm in activity following splenectomy. PMID- 4223453 TI - Differential diagnosis of visceral from somatic back pain. PMID- 4223454 TI - The action of cytostatic agents on the chromosomes of human leukocytes in vitro (preliminary communication). PMID- 4223455 TI - [Problems in the pathogenesis of cardiac insufficiency]. PMID- 4223456 TI - Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. I. An associated sodium-activated transphosphorylation. PMID- 4223457 TI - Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. II. Effects of N-ethylmaleimide and other sulfhydryl reagents. PMID- 4223458 TI - [Cancer of the bladder recurring in the abdominal wall]. PMID- 4223459 TI - [Cardiogenic bronchial stenosis in endocardial fibroelastosis]. PMID- 4223460 TI - [Incidence of occupational dermatoses in Czechoslovakia in 1954-63]. PMID- 4223461 TI - [Fascial fat herniation causing backache]. PMID- 4223462 TI - Development of the steady potential of the brain of chick embryos. PMID- 4223463 TI - Comparative pathophysiology of the paroxysmal electroencephalogram. Paroxysmal electroencephalogram (spike and wave activity) in the lizard (Lacerta agilis). PMID- 4223464 TI - [Anoxia tolerance of the neonatal nervous system (in the rabbit and cat)]. PMID- 4223465 TI - Developmental changes in the protein composition of heart muscle in the rat. PMID- 4223466 TI - Adaptation of rats of different ages to forced intake of a 2 per cent NaC1 solution without the occurrence of salt hypertension. PMID- 4223467 TI - The incorporation of S35 methionine into proteins of denervated and reinnervated muscle. PMID- 4223468 TI - Optimum conditions for studying autoiodoproteolysis of 127-I-thyroglobulin in rats. PMID- 4223469 TI - Changes in the protein content of plasma during blood losses in rats. PMID- 4223470 TI - Changes in haemoglobin fractions separated on CM-sephadex in normal newborn rats and in newborn rats after repeated blood losses. PMID- 4223472 TI - Changes in the membrane potential of cortical cells during spreading depression. PMID- 4223471 TI - Studies on the glycoproteins of human seminal plasma. PMID- 4223473 TI - Decerebrate control of primary afferent depolarisation evoked by adequate stimulation of cutaneous receptors. PMID- 4223474 TI - The effect of thalamic spreading depression on electric activity in the caudate nucleus and the hippocampus in rats. PMID- 4223475 TI - Optic evoked potentials in children, using different stimulation frequencies. PMID- 4223476 TI - The effect of increased sodium chloride intake on the rate of formation and retention of alimentary conditioned reflexes in normally and prematurely weaned rats. PMID- 4223477 TI - Iodine, solid diet, water and milk intake by lactating rats and their offsprings. PMID- 4223478 TI - The effect of thyroidectomy at early ontogenetic stages upon oxidative processes in the rat brain. PMID- 4223479 TI - Fat content and lipoproteinase activity in muscles of male rats with increased or reduced motor activity. PMID- 4223480 TI - A comparison between 18 to 20-year-old students with average physique and trained individuals. PMID- 4223481 TI - Development of the relationship between aerobic capacity and the circulatory and respiratory reaction to moderate activity in boys 11-13 years old. PMID- 4223482 TI - Capacitance plethysmography of the nasal mucous membrane in man. PMID- 4223483 TI - The breakdown of L-leucyl-p-nitroanilide by serum and tissue homogenates. PMID- 4223484 TI - Osmotic resistance of leucocytes of some laboratory animals. PMID- 4223485 TI - A comparison of the practical applicability of two methods used for the evaluation of the hypoxic reaction: factor analysis, multidimensional regression analysis. PMID- 4223486 TI - The safety of physically disabled drivers. PMID- 4223487 TI - Syngens of Paramecium aurelia in some regions of Moscow and Leningrad. PMID- 4223488 TI - Synergism in recalcitrant acne vulgaris. A report of good results in 78 percent of patients who had failed to respond to other therapy methods. PMID- 4223489 TI - The future role of local health authorities in the day care of the young child. PMID- 4223490 TI - [Structure and reactions of the area postrema in man]. PMID- 4223491 TI - Role of the medical social worker in patient disposition. PMID- 4223493 TI - Occupational therapy and pre-vocational testing. PMID- 4223492 TI - Physical therapy and rehabilitation procedures related to industry. PMID- 4223494 TI - Management's role in the utilization of the disabled. PMID- 4223495 TI - Diagnosis and disability evaluations including special measurements. PMID- 4223496 TI - [Studies on intraperitoneal adhesions. 2. Experimental studies on prevention and prophylaxis of postoperative adhesions]. PMID- 4223497 TI - [Clinical and experimental studies of plasmin system in hypothermia and general anesthesia during surgical operation]. PMID- 4223498 TI - [Changes in the behavior of acne vulgaris during the menstrual cycle]. PMID- 4223499 TI - Differential staining of acid glycosaminoglycans (mucopolysaccharides) by alcian blue in salt solutions. PMID- 4223501 TI - An assessment of work opportunities for the handicapped in the philippines. PMID- 4223500 TI - A new ion association-fractionation technique for identifying individual mucopolysaccharides and other polyanions in tissue sections. PMID- 4223502 TI - [ATPase in the sarcoplasmic reticulum, with special reference to the character of ATPase in the relaxing factor]. PMID- 4223503 TI - [ATPase in mitochondria]. PMID- 4223504 TI - [ATPase in photosynthetic organisms]. PMID- 4223505 TI - [ATPase in plants and microorganisms]. PMID- 4223506 TI - [ATPase in bacteria and bacteriophages]. PMID- 4223507 TI - [Non-ATPase ATP-hydrolyzing enzymes and ATPase]. PMID- 4223508 TI - [Histochemical studies on the behavior of alkaline phosphatase, adenosine triphosphatase, DPNH diaphroase and acid phosphatase in mouth mucosa and salivary glands in experimental acute lead poisoning]. PMID- 4223509 TI - Distribution of glycosaminoglycans, hydroxyproline and calcium in healing fractures. PMID- 4223510 TI - Fibrinolytic and proteolytic activity in acute and chronic leukemia. PMID- 4223511 TI - [Gross pathological examination of the central nervous system]. PMID- 4223512 TI - Histochemical study of acid mucopolysaccharides in the oviduct gland of Cynips folii. PMID- 4223513 TI - Histochemistry of parablastomatous connective tissue. PMID- 4223514 TI - Intracellular glycogen and other polysaccharides in human epidermal tumours. PMID- 4223515 TI - The prevalence of handicapping conditions in childhood. PMID- 4223516 TI - [Result of the use of actinospectacin (spectinomycin) in a surgical clinic]. PMID- 4223517 TI - Clinico-hemodynamic correlations in ventricular septal defect in childhood. PMID- 4223518 TI - Effect of L-histidine on hepatic histidine ammonia-lyase & histidine-pyruvate aminotransferase levels in rats. PMID- 4223519 TI - Occurrence of L-amino: 2-glyoxylate aminotransferase in lower plants. PMID- 4223521 TI - Enzymatic preparation of (--) & (+) isomers of citramalic acid. PMID- 4223520 TI - Deamination of amino acids by Azotobacter chroococcum. PMID- 4223522 TI - Synthesis of phospholipid in the blood of patients with essential hypertension. PMID- 4223523 TI - Activities of some enzymes of pentose phosphate pathway of malignant cervix uteri during various stages of malignant growth. PMID- 4223524 TI - Synthesis of an unstable functional ribonucleic acid in germinating wheat. PMID- 4223525 TI - Studies on horse antibodies. I. Development of antibody in different fractions of serum during immunization of horse with diphtheria toxoid. PMID- 4223526 TI - Studies on experimental protein malnutriton. I. Effect of threonine deficiency on glucose-6-phosphate metabolizing enzymes of rat liver. PMID- 4223527 TI - Incorporation of glycine-1-14C into tissues & adult rats after protein depletion & repletion. PMID- 4223528 TI - Availability of nicotinic acid in jowar (Sorghum vulgare). PMID- 4223529 TI - Interdependence of dietary protein & vitamins in metabolism. II. Interdependence of vitamin A, ascorbic acid & protein in metabolism. PMID- 4223530 TI - Role of vitamin A in sulphate metabolism: 3--Sulphate activation in hypervitaminotic A rats. PMID- 4223531 TI - Purification of ox brain acetylcholinesterase. PMID- 4223532 TI - Regulation of arginine biosynthesis in Vibrio cholerae. PMID- 4223533 TI - Neurotoxic properties of N-substituted oxamic acids. PMID- 4223534 TI - Metabolism of coumarin derivatives: a note on the urinary metabolites of calophyllolide, 4-phenylumbelliferone & 4-phenyl-7-methylumbelliferone. PMID- 4223535 TI - Purification & physical properties of a goat intestinal esterase. PMID- 4223536 TI - Chronic respiratory diseases--a mushrooming challenge. PMID- 4223537 TI - Desiccated thyroid U.S.P. or sodium L-thyroxine? PMID- 4223538 TI - Change of philosophy. PMID- 4223539 TI - Dermatologic cosmetic surgery. PMID- 4223540 TI - Recent developments in hair preparations. PMID- 4223541 TI - Evaluation of dermatologic creams containing female hormones. PMID- 4223542 TI - A census of women physicians in the Washington, D.C. Metropolitan area. PMID- 4223543 TI - My mother, the Doctor. Another solution to a much-discussed problem. PMID- 4223544 TI - Studies on heart phosphofructokinase. Purification, crystallization, and properties of sheep heart phosphofructokinase. PMID- 4223546 TI - Low back pain. PMID- 4223545 TI - Purification and properties of a tropomyosin-containing protein fraction that sensitizes reconstituted actomyosin to calcium-binding agents. PMID- 4223548 TI - Diagnosis and conservative treatment of ordinary low back pain. PMID- 4223547 TI - Familial mongolism by a G--G mosaic carrier. PMID- 4223549 TI - [On neuroradiology of atrophic brain processes with special reference to differential diagnostic possiblities]. PMID- 4223550 TI - [Contribution to the occupational development of infantile cerebral palsy patients]. PMID- 4223551 TI - Huntington's chorea, dysphagia and death. PMID- 4223552 TI - The incidence of osteoporosis in normal women: its relation to age and the menopause. PMID- 4223553 TI - An attempt for direct phage typing of pathogenic staphylococci. PMID- 4223554 TI - Medical self-help and nutrition courses in Central America. PMID- 4223555 TI - New drugs: the AMA and FDA roles. PMID- 4223556 TI - Hearing aids for hard of hearing patients. PMID- 4223557 TI - Extraovular saline-induced abortion. PMID- 4223558 TI - [Action on acne vulgaris by ovulation inhibitors]. PMID- 4223559 TI - [Inquiries into the course of experimentally induced myocarditis and arthritis in animals which had survived acute radiation disease]. PMID- 4223560 TI - Studies on the role of prophylactic desensitization in experimental myocarditis. PMID- 4223561 TI - [Blood level changes of macroergic phosphates in experimental myocarditis]. PMID- 4223562 TI - [On the protector effect of Acanthium. I]. PMID- 4223563 TI - [Early histochemical changes of some nucleoproteins, polysaccharides, and enzymes in the kidney and liver of white rats under the influence of sublimate]. PMID- 4223564 TI - [Morphological changes of the atrioventricular bundle in various conditions of the cardiac blood supply with cases of a sudden cardiac death]. PMID- 4223565 TI - [On some microcrystalline reactions to detect Lidol and their use in forensic chemical tests]. PMID- 4223566 TI - [Possibilities of extracting atarax from parts of internal organs and its determination by means of microcrystalline tests]. PMID- 4223567 TI - [On the problem of obtaining precipitating polio antigens]. PMID- 4223568 TI - [Isoadsorptive point of very soluble crystal salts. II. On the purity of sodium chloride]. PMID- 4223569 TI - [Is mistletoe an old cancer remedy?]. PMID- 4223570 TI - [Synoptic tables in medical literature and Agricola's and Ramus' logic]. PMID- 4223571 TI - [Morphological peculiarities of the heart septum and its historical significance]. PMID- 4223572 TI - [Rainbow and refraction number]. PMID- 4223573 TI - [Curative herbs from Novaesium (Neuss, Rhineland) in the Roman period]. PMID- 4223574 TI - [De partibus sensilibus (On the sensitive parts)]. PMID- 4223575 TI - [On therapy of malaria in the 17th century]. PMID- 4223576 TI - [Dr. Arthur Czwalina]. PMID- 4223578 TI - Evaluation of the 2-minute sit-up test as a measure of muscular endurance and strength. PMID- 4223579 TI - [On the possible association between maternal viral hepatitis and Down's syndrome]. PMID- 4223577 TI - Separation of adenosine diphosphate--adenosine triphosphate-exchange activity from the cerebral microsomal sodium-plus-potassium ion-stimulated adenosine triphosphatase. AB - 1. A microsomal fraction from ox cerebral cortex catalysed [(14)C]ADP-ATP exchange at a speed similar to that at which it liberated P(i) from ATP in the presence of Na(+), K(+) and Mg(2+). 2. Repeated washing the fraction with MgATP solutions solubilized most of the exchange activity and left the adenosine triphosphatase insoluble and little changed in activity. The exchange activity was accompanied by negligible adenosine-triphosphatase activity and was enriched by precipitation at chosen pH and by DEAE-Sephadex. At no stage was its activity affected by Na(+), K(+) or ouabain. 3. The washed microsomal fraction was exposed to a variety of reagents; a sodium iodide-cysteine treatment increased both adenosine-triphosphatase and exchange activities, as also did a synthetic zeolite. Preparations were obtained with exchange activities less than 3% of their Na(+)-plus-K(+)-stimulated adenosine-triphosphatase activity. Some contribution to the residual exchange activity was made by an adenylate kinase. 4. Thus over 95% of the microsomal ADP-ATP-exchange activity does not take part in the Na(+)-plus-K(+)-stimulated adenosine-triphosphatase reaction. Participation of some of the residual 3% of the ADP-ATP-exchange activity has not been excluded, but there appears no firm evidence for its participation in the adenosine triphosphatase; the bearing of this conclusion on mechanisms proposed for the Na(+)-plus-K(+)-stimulated adenosine triphosphatase is indicated. PMID- 4223580 TI - An outbreak of infection due to Staphylococcus aureus phage type 80/81 in a veterinary school. PMID- 4223581 TI - [On a fatally progressing disease of 3 brothers under the picture of erythrodermia desquamativa Leiner]. PMID- 4223582 TI - Fibrinolysin studies in hemophilia. PMID- 4223583 TI - The reversible activation of mitochondrial ATPase by high pH. PMID- 4223584 TI - [The effect of ionizing x-rays on the histochemical reactions in the adrenals of rats]. PMID- 4223585 TI - Lumbar facet fractures following disk surgery. PMID- 4223586 TI - Ultrastructure of the placenta in hypertensive states. The localization of enzmes hydrolysing adenosine triphosphate in placentae from normal and toxaemic pregnancies. PMID- 4223587 TI - [Experiences in epoxy-resin sensitization]. PMID- 4223588 TI - [Energy-rich phosphorus compounds, and creatinase and ATPase activity of the heart muscle in experimental myocardial infarction]. PMID- 4223589 TI - [Dental caries problems of early childhood, and their prevention]. PMID- 4223590 TI - Children's dentistry--a challenge. PMID- 4223591 TI - Existence of an apparent metabolic block in human granulation tissue. PMID- 4223592 TI - [Relationship between the width of the 6 anterior teeth and the position of the first permanent molars on normal occlusion among the child population of the Thessalonike region]. PMID- 4223593 TI - [Mucinosis papulosa--scleromyxedema]. PMID- 4223594 TI - Advance notice of dental surgery promotes good psychological responses. PMID- 4223595 TI - A controlled trial of benzoyl peroxide and precipitated sulfur cream in acne vulgaris. PMID- 4223596 TI - Low back pain in men receiving workmen's compensation. PMID- 4223598 TI - Some aspects of the bacteriology of acne vulgaris. PMID- 4223597 TI - Abnormal patterns of growth and development in mongolism. An anthropometric study. PMID- 4223599 TI - [Experimental urinary tract infections. I. On connection between "Bradykinin" and fibrinolytic enzyme system]. PMID- 4223600 TI - [Comment on the preservation of infectious activity of vaccinia virus using glycerin]. PMID- 4223601 TI - [Vaccination of school-age children against pertussis]. PMID- 4223602 TI - [Analysis of tetanus incidence in Slovakia. (II. 1956-64)]. PMID- 4223603 TI - [Disinfectant hexachlorophene soap in infectious work]. PMID- 4223604 TI - [On the sensitivity of some yeasts to nystatin and amphotericin B]. PMID- 4223605 TI - [A novelty for microbiological laboratories]. PMID- 4223607 TI - Adenocarcinoma of the cervix uteri. Review of cases at the Dr. I. Gonzalez Martinez Oncologic Hospital. PMID- 4223606 TI - Home care program for the chronically ill and the aged of the west regional district, Mayaguez, Puerto Rico. PMID- 4223608 TI - Diffuse glycogenosis. PMID- 4223610 TI - Air pollution and the heart. PMID- 4223609 TI - Hospital practice in Appalachia; report on the Albert Schweitzer Memorial Hospital, Balsam Grove, North Carolina. PMID- 4223611 TI - Air pollution and the lung. PMID- 4223612 TI - Four of us: sketches of the four women ophthalmologists of the Massachusetts Eye and Ear Infirmary. PMID- 4223613 TI - [Backaches of the female from the gynecologic viewpoint]. PMID- 4223614 TI - An immunofluorescent study on anti-synovial tissue antibody in the body fluid from patients with rheumatoid arthritis. PMID- 4223615 TI - Cellular antibody in mice bearing Ehrlich cancer. 3. Relationship of cellular antibody to serum antibody. PMID- 4223616 TI - Fine structure of negatively stained adenovirus type 12. PMID- 4223617 TI - The relationship between histochemical enzyme activities of brain tumors and clinical features of the patients. PMID- 4223618 TI - Studies on the function of reticulo-endothelial system. II. Effects of the R.E.S. blocking with macro-molecular PVP on the lymphoid cell reproduction and the production of serum antibody. PMID- 4223619 TI - Morphological and functional changes in isolated chloroplasts under the influence of oleate. PMID- 4223620 TI - Reducing failure in vocational rehabilitation. PMID- 4223621 TI - Ocular dracunculosis. PMID- 4223622 TI - Enzymatic adaptation: molecular basis for cardiac glycoside action? 1. Increase in rat heart actomyosin and mitochondrial ATPase specific activities following digoxin injection. PMID- 4223623 TI - [Studies on reactions to light in psoriasis patients]. PMID- 4223624 TI - [On the angiocavernous form of the fibrocystic lung]. PMID- 4223625 TI - Muscle spindle activity in dystonic and spastic monkeys. PMID- 4223627 TI - [The possibility of using porcine kidney tissue cultures for the quantitative determination of Myxovirus influenzae C]. PMID- 4223626 TI - Cordotomy for intractable pain of nonmalignant origin. Review of twenty cases. PMID- 4223628 TI - [Rabbits as a possible source of toxoplasmic infection in man]. PMID- 4223629 TI - Neonatal congestive heart failure as the presenting symptom of cerebral arteriovenous malformation. PMID- 4223630 TI - [Keratoconus secondary to rosacea keratitis]. PMID- 4223631 TI - Serum mucopolysaccharides in alloxan and steroid diabetes. PMID- 4223632 TI - The liver in lipidosis. An electron miscroscopic and histochemical study. PMID- 4223633 TI - Hyperuricemia with self-mutilation and choreo-athetosis. Lesch-Nyhan syndrome. PMID- 4223634 TI - Effects of cystamine and cysteamine on the adenosine-triphosphatase activity and oxidative phosphorylation of rat-liver mitochondria. AB - 1. Cystamine (2,2'-diaminodiethyl disulphide) caused an unmasking of mitochondrial adenosine triphosphatase and a leakage of Mg(2+) from the mitochondria, and decreased the stimulation of adenosine triphosphatase by 2,4 dinitrophenol. When Mg(2+) was added, cystamine potentiated the activation of adenosine triphosphatase by 2,4-dinitrophenol. 2. Cystamine was without effect on the adenosine triphosphatase of disrupted mitochondria. 3. Cystamine was moderately potent as an uncoupling agent and as an inhibitor of the [(32)P]P(i) ATP exchange reaction. 4. Cysteamine (2-aminoethanethiol) was without the above effects, when special precautions were taken to counteract its autoxidation. 5. The effects of cystamine should probably be ascribed to its disulphide group, since the diamine cadaverine protected slightly against the loss of Mg(2+) and the decrease of 2,4-dinitrophenol-stimulated adenosine-triphosphatase activity caused by aging of the mitochondria. It is suggested that cystamine acts by a breakdown of mitochondrial permeability barriers. PMID- 4223636 TI - Cardiac myofibrillar ATPase activity in hypophysectomized or thyroidectomized rats. PMID- 4223635 TI - The mutagenic properties of the nucleosides of pyrimidine analogues in Drosophila melanogaster. PMID- 4223638 TI - Report on a laminar flow surgical facility. PMID- 4223637 TI - Controlling static in the clean room. PMID- 4223639 TI - Kinetic evidence for multiple binding sites on phosphofructokinase. PMID- 4223640 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. 8. Properties of a factor conferring oligomycin sensitivity on mitochondrial adenosine triphosphatase. PMID- 4223641 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. IX. Reconstruction of oligomycin-sensitive adenosine triphosphatase. PMID- 4223643 TI - [Pharmacognosy of some species of woodruff from the flora of Azerbaijan]. PMID- 4223642 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. X. Correlation of morphology and function in submitochondrial particles. PMID- 4223645 TI - [Surgical procedures during celioscopy]. PMID- 4223644 TI - [Activity of public voluntary councils to promote work of pharmacies in the Leningrad region]. PMID- 4223646 TI - [Auxiliary instruments for celioscopic tubal diagnosis]. PMID- 4223647 TI - Eight backward pupils and i.t.a. PMID- 4223648 TI - Number work at Craig-y-Parc. PMID- 4223649 TI - A time for fresh evaluation. PMID- 4223650 TI - An outlet after school. PMID- 4223651 TI - [Effects of occupationally caused CO intoxications on the organs of smell, hearing and equilibrium]. PMID- 4223652 TI - [The pain phenomenon in children during dental treatment]. PMID- 4223653 TI - Use of ultrasound in the diagnosis of pericardial effusion. PMID- 4223654 TI - [Mongolism and the endocrine glands]. PMID- 4223655 TI - [Study of alkaloids contained in some species of Delphinium growing in Azerbaijan]. PMID- 4223656 TI - Clinico-pathological conference. PMID- 4223657 TI - Derivatives of 2-azabicyclo[2.2.2]octane. II. PMID- 4223659 TI - [Comment on laparoscopy]. PMID- 4223658 TI - Down's syndrome with a familial D/D reciprocal translocation and a G/G chromosome. PMID- 4223660 TI - [Soviet legislation on the narcotics law and on drug addiction]. PMID- 4223661 TI - The effect of clomiphene on hormone excretion in patients with galactorrhoea. PMID- 4223662 TI - Metabolism of dehydroepiandrosterone and dehydroepiandrosterone sulphate by the human foetus at midpregnancy. PMID- 4223663 TI - Distribution of some steroid sulphokinases in foetal human tissues. PMID- 4223664 TI - [On the origin of the acid mucopolysaccharides of the nephron, studied in vitro]. PMID- 4223665 TI - [Changes in the physical development on school-children in the Kirghizian SSR]. PMID- 4223666 TI - [Experience with the sanitary protection of the Nura River]. PMID- 4223667 TI - [Apropos of the lighting in school gymnasiums]. PMID- 4223668 TI - [Lysogenicity of some staphylococci]. PMID- 4223669 TI - [On the pathogenesis of dermatitis and eczema developing after contact with urea formaldehyde resins]. PMID- 4223670 TI - [Occupational dermatitis due to BF-4 glue and acetone]. PMID- 4223671 TI - [The effect of neosone D on the skin]. PMID- 4223672 TI - [Prevention of microtraumatism and pyogenic diseases among workers in Hunger Steppe construction enterprises]. PMID- 4223673 TI - Studies on Na+-K+-activated adenosine triphosphatase. XVI. Its absence from the cation transport system of Ulva lactuca. PMID- 4223674 TI - An immunochemical study of human plasminogen and plasmin. PMID- 4223675 TI - [Na+-K+-active inheritable adenosinetriphosphatase system: the effect of Triton-X 100 on the SH groups]. PMID- 4223676 TI - Mucopolysaccharides in experimental hepatic fibrosis. PMID- 4223677 TI - [Clinical significance of the erythrocyte sedimentation rate in the Teberda mountain health resort]. PMID- 4223678 TI - [A case of drug allergy with generalized eruptions]. PMID- 4223679 TI - [Lumbar sympathetic nerve block in acute lumbago]. PMID- 4223680 TI - [Erythroderma developing in the treatment of psoriasis with antimalarials]. PMID- 4223681 TI - [Studies on the chemical assay of urinary 17-KGS, normal values in women and its changes induced by administered gestagens]. PMID- 4223682 TI - Nerve implants in botulinum poisoned mammalian muscle. AB - 1. In albino rats the botulinum poisoned gastrocnemius muscle was supplied with an accessory motor nerve in order to investigate whether muscle fibres with structurally intact but non-transmitting synapses would accept additional innervation. As a control similar operations were made in unpoisoned rats.2. One to three months after nerve implantation the muscles were examined histologically for the presence of a new end-plate zone. In botulinum treated muscles 1662 +/- 165 (mean +/- S.D.) of new end-plates were found. In the control animals only a few (90 +/- 13) were observed in the immediate vicinity of the implanted nerve trunk.3. Following recovery from the paralysing action of botulinum toxin electrical stimulation of both the implanted and the original motor nerve evoked strong mechanical twitches in the gastrocnemius muscle.4. When the nerves were stimulated simultaneously little or no summation of tension occurred, indicating that presumably many of the muscle fibres with new end-plates also had functionally intact junctions from the original nerve. The presence of two end plates in a muscle fibre was confirmed in a few experiments on single curarized fibres by intracellular recording of end-plate potentials on stimulation of each nerve. PMID- 4223684 TI - [The research problem on the pathophysiology of lumbago]. PMID- 4223685 TI - [Synanthropic flies of the town of Grozny]. PMID- 4223683 TI - Reflex and cerebellar influences on alpha and on 'rhythmic' and 'tonic' gamma activity in the intercostal muscle. AB - 1. Efferent intercostal alpha and gamma activity and afferent intercostal muscle spindle activity were studied in decerebrate cats in response to stimulation of the anterior lobe of the cerebellum and to postural and other reflexes.2. Low threshold intercostal responses were elicited from lobuli IV and V of the anterior lobe of the cerebellum.3. The existence of two functionally different types of intercostal gamma neurones has been confirmed. These are the ;rhythmic' or ;specifically respiratory' gamma neurones, and the ;tonic' gamma neurones.4. In response to cerebellar stimulation, facilitatory, inhibitory and diphasic tetanic and post-tetanic effects were obtained from alpha and the two types of gamma fibres in both external and internal intercostal nerve branches.5. Generally both inspiratory and expiratory alpha and gamma activity was facilitated in response to tetanic stimulation at contralateral stimulus sites, and inhibited in response to stimulation of ipsilateral sites.6. ;Rhythmic' gamma activity appeared to be rather closely linked to the respiratory alpha activity but the balance between ;rhythmic' gamma and alpha was often changed in response to cerebellar stimulation, as indicated by the responses of primary muscle spindle afferents.7. The ;tonic' gamma neurones were as a rule more responsive to cerebellar stimulation than were the alpha and ;rhythmic' gamma neurones. Long lasting post-tetanic effects were much more prominent in the ;tonic' gamma fibres than in the alpha or ;rhythmic' gamma fibres.8. ;Rhythmic' gamma activity was abolished after cervical transections of the cord. ;Tonic' gamma activity remained in the spinal preparations although usually at a different discharge rate.9. ;Tonic' gamma neurones were more responsive than the ;rhythmic' gamma neurones to the proprioceptive gamma reflex elicited by passive movements of the chest wall as well as to other spinal and supraspinal reflexes.10. Both ;dynamic' and ;static' gamma fibres seem to be represented in the group of ;tonic' intercostal gamma neurones.11. The significance of the results are discussed with regard to the following two main points: (a) integration of respiratory and postural functions of the intercostal muscles; (b) cerebellar control of the alpha-gamma balance in active contractions and passive relaxations. PMID- 4223686 TI - [Heterotropic ossification in an abdominal cicatrix. Case report]. PMID- 4223687 TI - Relapsing polychondritis. Analytical literature review and studies on pathogenesis. PMID- 4223688 TI - Radiocarbon cholesterol turnover in cholesterol pericarditis. PMID- 4223689 TI - [Mucopolysaccharide substances and glycogen in chronic hypertrophic and atrophic pharyngitis. Histochemical contribution]. PMID- 4223691 TI - Mitochondrial membrane ghosts produced by lipid peroxidation induced by ferrous ion. II. Composition and enzymatic activity. PMID- 4223692 TI - [Clinico-pathological conference. Fainting and fatigability]. PMID- 4223690 TI - [Excoriative acne of young women--from the psychiatric viewpoint]. PMID- 4223693 TI - Interactions of epsilon-aminocaproic acid with the thrombin clotting and fibrinolytic systems. PMID- 4223694 TI - [Effect of sodium adenosine triphosphate on the glycogen content of the hypertrophic heart muscle in rats]. PMID- 4223695 TI - [Dermatosis papulosa nigra (Castellani 1925)]. PMID- 4223696 TI - Huntington's chorea. A multidisciplinary study of affected parents and first generation offspring. PMID- 4223697 TI - A study of the oral toxicity of calcium chloride in dairy cows. AB - The effects of oral administration of calcium chloride solutions to dairy cows were studied. When a 0.3 per cent solution was given ad libitum, and as the sole source of water for a period of 75 days, we observed no significant changes in feed consumption, body weight or milk production. The average daily water intake was increased by approximately 20 per cent, and signs of slight gastro-intestinal irritation were seen. No major changes in blood hemoglobin levels, hematocrits, total and differential white cell counts or thrombocyte numbers could be attributed to the treatment. We observed no significant effect on the serum calcium, chloride, magnesium, potassium, or sodium content. The level of inorganic phosphate in the serum rose to higher, but still normal values. During the entire experiment the urine pH was abnormally acid for dairy cows. Electrocardiograms were taken after 45 days of calcium chloride administration, and they appeared normal. When 0.1 and 0.2 per cent solutions were given as the sole source of water for a period of 81 days, the cows remained in good condition, and we observed no changes in appetite, body weight or milk production. In general, dairy cows will refuse to drink calcium chloride solutions when the concentration exceeds 0.5 per cent, even when they have been deprived of water for 18-24 hours. On the other hand, since the administration of lower concentrations for periods of 75 and 81 days did not cause any clinical sign of disease, it seems that on farms where more than one source of water are usually available, poisoning of dairy cattle by calcium chloride in solution is quite unlikely. PMID- 4223699 TI - The formation of plaques by African horse sickness viruses and factors affecting plaque size. AB - Under agar overlay, large and small plaques were observed for African Horse Sickness viruses. The purification of large plaques by cloning was possible. By addition of protamine sulfate to the agar overlay only large plaques were produced. The plaque size variation can not be a suitable marker for determination of variants of this virus since under methyl cellulose and starch gel overlays homogenous plaques were noticed. PMID- 4223698 TI - Comparative pathologic and hematologic effects in various species fed cholesterol and fats. AB - The hematologic response in various animal species fed cholesterol and fat differed with the species and sex. Male rabbits, chickens and guinea pigs could not adequately comensate for the demand for increased red cell production and developed anemia. Female guinea pigs given added cholesterol and fat maintained adequate blood cell production but may have become anemic if the test period had been extended. Bone marrow production was increased in male rats and was sufficient to compensate for red cell loss. Blood and bone marrow values were not altered in female chickens by the dietary treatment. Fatty changes in the liver were common to all species fed added cholesterol and fat but gastric lesions were seen only in the rabbit. PMID- 4223700 TI - Canada's oldest veterinary practice. PMID- 4223701 TI - Genetic counseling and Down's syndrome. PMID- 4223702 TI - [Investigations in the field of obtaining nicotinic acid amide]. PMID- 4223703 TI - Use of carisoprodol preparations in the management of the lumbosacral syndrome. PMID- 4223704 TI - [Transformations of dehydroepiandrosterone by embryonic chicken gonads cultivated in vitro]. PMID- 4223705 TI - [Action of retinal on the in vitro transformation of transdehydroepiandrosterone into androstenedione by the adrenal cortex of the white rat]. PMID- 4223706 TI - Induced tolerance in turkeys to aflatoxin poisoning. AB - The consumption of moderately poisonous levels of toxic groundnut meal by turkey poults induced a degree of tolerance to aflatoxin Poults thus ;conditioned' gained more than ;unconditioned' birds on successively higher levels of aflatoxin and were enabled to survive and gain on rations which killed mature turkeys. Ingestion of aflatoxin led to marked alterations in the serum electrophoretic patterns followed in a few weeks by a return to nearly normal patterns. Subsequent increases in aflatoxin intake induced only minimal alternations in the serum patterns but the tolerance appeared unrelated to the hepatotoxic effect because extensive pathological changes developed in the liver. PMID- 4223707 TI - A note on some helminths of Manitoba chickens. PMID- 4223709 TI - Exudative epidermitis in pigs. Clinical studies and preliminary transmission trials. AB - Four outbreaks of an infectious, exudative skin disease of 6 to 10 week-old weaned pigs, are described. The disease was seen in fattening barns where weanlings from several sources were mixed. The disease was characterized in the peracute form by the formation, over the entire body, of a brown, greasy, odorous exudate, by loosening of the hoofs, by severe depression, dehydration and death in 3 to 5 days. In the acute form the lesions were identical, but their evolution slower, the mortality was high, and survivors severely stunted. Secondary infections seemed largely responsible for mortality in the acute form. Subacute infections were frequent and characterized by the formation of few to many circular exudative foci which became dry and cleared up completely in about 2 weeks. Antibiotics and mineral supplements were of no value in controlling or preventing the development of lesions or mortality.Minimal-disease pigs were exposed to diseased pigs from 3 of the 4 outbreaks studied and in all cases they developed typical lesions and could transmit the infection to other pigs. Bacteriological examination of field and experimentally produced cases gave inconclusive results pending further study. PMID- 4223710 TI - [Handicapped drivers in traffic]. PMID- 4223708 TI - Dimethyl sulfoxide (DMSO). PMID- 4223711 TI - [300 cases of laparoscopy]. PMID- 4223712 TI - The chemical dimensions of a healing incision. PMID- 4223713 TI - [Change in the total protein and protein fractions in the serum of sheep fetuses of the Azerbaidzhan Mountain merino breed]. PMID- 4223714 TI - [The method for histochemical demonstration of Na-K-Mg-ATP-ase of the rat cornea]. PMID- 4223715 TI - Properties of adenosinetriphosphatase in sub-cellular particles of mouse melanoma. PMID- 4223716 TI - [Results of examination of the employees of Cracow plants for detection of occupational skin diseases]. PMID- 4223718 TI - Bangkok patients reject wheelchairs. PMID- 4223717 TI - The sea climate influence on some functions of the suprarenal glands. PMID- 4223719 TI - On the antigenic composition of diphtheria toxin and toxoid. PMID- 4223720 TI - [Experiences with hysteroligamentoplexy according to C. Stanca]. PMID- 4223721 TI - [Study of a pair of dizygotic twins, one a mongoloid with trisomy 21 and the other normal, with transitory chimerism of cells with trisomy 21]. PMID- 4223722 TI - The late apical systolic murmur. Clinical, hemodynamic and angiographic observations. PMID- 4223723 TI - A fatal complication of aortic valve fenestration. Coronary ostial obstruction by an engaged embolus. PMID- 4223724 TI - The continued management of the handicapped child. PMID- 4223725 TI - Androgenic steroid complexes with p-bromophenol. PMID- 4223726 TI - [Alimentary epidemic of infectious hepatitis]. PMID- 4223727 TI - [Isolation of tick-born encephalitis virus from Ixodes ricinus L. ticks in natural habitat in the surroundings of Bouzov]. PMID- 4223728 TI - [Shigella mucinase. II. The influence of some physical and chemical factors on its activity]. PMID- 4223729 TI - [Sterilization with ethoxene]. PMID- 4223730 TI - [Incidence of positive reactions to the rheumatoid factor (RF) in patients with influenza]. PMID- 4223731 TI - [Application of the CAMP test in diagnostic practice]. PMID- 4223732 TI - [Finding of a rare species of dermatophyte in an onychomycotic lesion]. PMID- 4223733 TI - [Sickle cell hemoglobin C disease]. PMID- 4223734 TI - [Thoughts on the problems of rheumatic diseases]. PMID- 4223736 TI - [A clinical case of chronic granulomatous and erythrodermal dermatomycosis caused by Trichophyton violaceum]. PMID- 4223737 TI - A lymphocyte-stimulating factor produced in vitro. PMID- 4223738 TI - [The dynamics of gliding of normal and grafted tendons]. PMID- 4223735 TI - Mucopolysaccharides of whole human spleens in generalized amyloidosis. PMID- 4223740 TI - [Intra-osseous capsulo-synovial inclusions]. PMID- 4223739 TI - [Articular ischemia in human and experimental pathology. The concept of vascular pannus]. PMID- 4223741 TI - [Vertebral arthrodesis for scoliosis by refreshing and apposition of autogenic cortico-spongy grafts. Remarks apropos of reparation osteogenesis and microscopical study of postoperative correction losses]. PMID- 4223742 TI - [Fractures of the tibial spines]. PMID- 4223743 TI - [Trial of experimental revascularization of the femoral head]. PMID- 4223744 TI - [Resection in the treatment of bone tumors]. PMID- 4223745 TI - [Fractures of the femur neck in children. (Study of 25 cases)]. PMID- 4223746 TI - [Skin necrosis of the lower extremity healed with staphylococcal phagolysates]. PMID- 4223747 TI - Inhibition of the effect of repetitive stimulation on spinal motoneurones of the cat by morphine and pethidine. PMID- 4223748 TI - [Effects of fading on the yield, the main components and the physicochemical properties of the volatile oil from Thymus vulgaris L. II]. PMID- 4223749 TI - Autoimmune phenomenon in eczema seborrhoeicum. PMID- 4223750 TI - The lifespan of red blood cells in experimental lead poisoning, studied with radioactive chromium 51-Cr. PMID- 4223751 TI - [Apropos of the treatment of acne with a synthetic estroprogestative agent]. PMID- 4223752 TI - [Estroprogestative agents, acne and female seborrhea]. PMID- 4223754 TI - The transmission of hog cholera virus by Trichinella spiralis larvae. AB - Studies have been carried out to determine (a) the possible role of T. spiralis larvae in the transmission of hog cholera virus and (b) to determine the effect of elevated swine temperature on the viability of trichinae. Trichina larvae from hog cholera infected swine were freed from diaphragmatic tissue by artificial digestion. Washed and disinfected larvae transmitted hog cholera virus while the supernatant digestive fluid did not transmit the virus. Infectivity of the virus was lost when the larvae were transmitted through albino rats before administration to swine. Temperature elevation of the swine did not affect the viability of the trichinae. PMID- 4223755 TI - [Examination of social aspects in the rehabilitation of disabled patients]. PMID- 4223753 TI - Hemolytic behavior of staphylococci isolated from cows' milk. AB - Patterns of hemolysis produced by staphylococci isolated from milk were investigated on media prepared with bovine, sheep, horse, and rabbit erythrocytes under a variety of cultural circumstances. Hemolytic patterns were sharper and easier to interpret on erythrocyte agar plates when incubated at 37 degrees C in an atmosphere containing 30% CO(2.) Alpha-hemolysin production was greatly enhanced in this environment and was not detected at times when cultures were grown in air only. This was also true of deltahemolysin but to a lesser extent. Very satisfactory identification of alpha, beta- and delta-hemolysins was obtained by streaking BEA plates with the unknown strains perpendicularly to a strain producing beta-hemolysin and incubating in 30% CO(2.) This procedure avoided use of erythrocytes of different species of origin and use of staphylococcal alpha-antitoxin. Prior action of the beta-hemolysin on bovine cells was found to completely inhibit hemolysis from alpha-hemolysin but the reverse was not true. A strain inhibiting beta-hemolysis in air failed to exhibit its antihemolytic properties for 24 hours when incubated in 30% CO(2.) Patterns of hemolysis within areas subject to multiple hemolysins were found to reflect the nature and relative strength of contributing hemolysins or antihemolysins and could be modified by the time sequence of exposure to certain hemolysins or antihemolysins. PMID- 4223756 TI - [The Sezary-Baccaredda syndrome: erythrodermal reticulosis with reticulemia]. PMID- 4223757 TI - [Experimental pathogenetic observations and clinical considerations on the subject of occupational eczema]. PMID- 4223758 TI - [Methods of conducting preventive mass screenings for detection of cancer and precancerous diseases of the stomach]. PMID- 4223759 TI - [From the history of medicine and public health of Archangel]. PMID- 4223760 TI - [Ia. V. Girshson--the 1st physician-psychiatrist in Kursk]. PMID- 4223761 TI - Influence of sex on the antiproteolytic activity of rat serum. PMID- 4223762 TI - Muscle spindles. PMID- 4223763 TI - Partial purification and characterization of sodium- and potassium-dependent adenosine triphosphatase from rat-heart muscle. PMID- 4223764 TI - Fractionation of acidic polysaccharides derived from a small group of chondrocytes. PMID- 4223765 TI - Unknown properties of the products of plasmin-degradation of fibrinogen and fibrin. PMID- 4223766 TI - Occupational therapy in the field of physical disabilities. PMID- 4223768 TI - Guidelines for a bioclean spacecraft assembly area. PMID- 4223767 TI - Automation can be an assistive device. PMID- 4223769 TI - [Seasonal features of immunization of small rodents in a natural focus of tick borne encephalitis in south taiga forests of the European plain]. PMID- 4223770 TI - [Warming of the climate and outbreaks of tick-borne encephalitis]. PMID- 4223771 TI - [Data on the investigation of the incidence of Q-fever infection in wild animals and birds in some areas of the Tselinny Region]. PMID- 4223772 TI - [Infestation with Rickettsia burnetii of blood-sucking arthropods in virgin lands of the Kokchetav Region]. PMID- 4223773 TI - [Some data on the leishmaniasis in the Turkmen SSR]. PMID- 4223774 TI - [The seasonal incidence of the house fly M. domestica vicina Macq in Lenkoran]. PMID- 4223775 TI - [The role of Russian scientists in control of parasitic diseases in Azerbaijan (150th anniversary of inclusion of Azerbaijan into Russia)]. PMID- 4223776 TI - [A case of quartan malaria in Baku]. PMID- 4223777 TI - [A natural focus of trichinellosis in Uzbekistan]. PMID- 4223778 TI - A Vermont program helps disabled rural homemakers. PMID- 4223779 TI - Inhibition of fibrinolytic and thromboplastic activity by Trasylol. PMID- 4223780 TI - [On mucopolysaccharide excretion in peripheral circulation disorders]. PMID- 4223781 TI - [Phage typing of staphylococci isolated in various groups of the Transcarpathian population]. PMID- 4223782 TI - [Lysogenic properties of plasma-coagulating strains of staphylococci]. PMID- 4223784 TI - [Clinical experimentation of a granulated antidiarrhea agent in 50 cases of infantile diarrhea of diverse etiology]. PMID- 4223783 TI - Studies of staphylococcal infections. II. The role of bacteriophage type, antibiotic resistance, coagulase, and other exotoxins in infections in embryonated eggs. PMID- 4223785 TI - Changes in psychologic test (WAIS) scores of older disabled persons during a vocational rehabilitation program. PMID- 4223786 TI - [Skin diseases in the "Zabrze" foundry]. PMID- 4223787 TI - [Autoradiographic and fluorescence microscopic studies of the aortic mucopolysaccharides following local influence of 90 Sr-90 Y-beta radiation]. PMID- 4223788 TI - Relation of increase in muscle mass to performance of hypertrophied right ventricle in the dog. PMID- 4223789 TI - Cardiac myosin adenosinetriphosphatase activity. Modifying factors and comparison with skeletal muscle myosin adenosinetriphosphatase activity. PMID- 4223790 TI - Management of acne vulgaris. PMID- 4223791 TI - [Introduction to lumbago]. PMID- 4223792 TI - [Metachromatic leukdystrophy (Sulfatidosis) and mucopolysaccharidosis associated in the same patient]. PMID- 4223793 TI - [Treatment of patients with rheumatoid arthritis in balneological health resorts of North Ossetia]. PMID- 4223794 TI - [Anti-elastase behavior during development of emphysematous diseases]. PMID- 4223795 TI - Reproduction in the ferret (Mustela furo). I. Uterine histology and histochemistry during pregnancy and pseudopregnancy. PMID- 4223796 TI - [Frequency and distrbution of pearl string ridges on the hands of mentally normal people and mongoloids]. PMID- 4223797 TI - [On the possibility of diagnosing cerebral fat embolism using electroencephalography]. PMID- 4223798 TI - [Cerebrospinal fluid substitution with Ifukoll following severe closed skull and brain trauma with cerebrospinal fluid hypotension]. PMID- 4223799 TI - [Experiences with the modified Eden-Hybinette operation]. PMID- 4223800 TI - [Late development of acoustic trauma (studies on 500 workers in a noisy environment. II.)]. PMID- 4223801 TI - [Enzyme determinations in surgical and injured patients]. PMID- 4223802 TI - [Sustitute tendonoplasty in patellectomy]. PMID- 4223803 TI - Identification of 3-beta, 17-beta-dihydroxyandrost-5-ene, 3-beta, 20-alpha dihydroxypregn-5-ene and epiandrosterone in human peripheral blood. PMID- 4223804 TI - Metabolism of 7-3H-dehydroisoandrosterone in patients with virilizing adrenal tumors. PMID- 4223805 TI - [Public funds for the severely handicapped]. PMID- 4223806 TI - [Medicotechnical aids for the handicapped. From a report on a study trip to the USA, England and the Netherlands]. PMID- 4223808 TI - A handicapped patient's plea: consider the whole person. PMID- 4223807 TI - Gas chromatographic-mass spectrometric studies on solvolyzable steroids in human peripheral plasma. PMID- 4223809 TI - Loss of antibiotic resistance in Staphylococcus aureus resulting from growth at high temperature. PMID- 4223811 TI - Hirschsprung's disease and mongolism. PMID- 4223810 TI - Some pitfalls in the valuation of cardiac chamber enlargement on chest roentgenograms. PMID- 4223812 TI - [Acne vulgaris. An attempt at its treatment]. PMID- 4223813 TI - Congenital aortic sinus aneurysms with particular reference to dissection of the interventricular septum. PMID- 4223814 TI - Preoperative and postoperative electrocardiogram in complete transposition of the great vessels. PMID- 4223815 TI - The temporal sequence of lymph flow in the right lymphatic duct in experimental chronic pulmonary edema. PMID- 4223816 TI - Clinical pathologic conference. PMID- 4223817 TI - The challenge of research on mucus. PMID- 4223818 TI - Acid mucopolysaccharide composition in human colon. PMID- 4223819 TI - Serum inhibitors of elastase, trypsin, and plasmin in chronic rheumatic diseases. PMID- 4223820 TI - Tritiated thymidine uptake by group G chromosomes of female individuals with Down's syndrome. PMID- 4223821 TI - Fungal infection of the nails. PMID- 4223822 TI - Cutaneous manifestations of drug toxicity. PMID- 4223823 TI - Effect of biotin on hair roots and sebum excretion in women with diffuse alopecia. PMID- 4223824 TI - [Report on lysotopes found in Staphylococcus aureus isolated from food]. PMID- 4223826 TI - [Differentiation of skeletal muscle in the white rat. 8. The adenosine triphosphatase activity]. PMID- 4223825 TI - [Studies on the mechanism of the hypotensive action of monoaminoxidase inhibitors]. PMID- 4223827 TI - [Danish studies on the status of care for the handicapped is called to our attention]. PMID- 4223828 TI - Industrial aspects of abdominal trauma. PMID- 4223829 TI - Medical testimony in a workmen's compensation case of hiatal hernia, bilateral vagotomy, pyloroplasty, and tube gastrostomy, showing the cross-examinations of the internists, radiologist, and surgeon called by respondents (defendants). PMID- 4223830 TI - [Problems of the early diagnosis and treatment of thromboembolism of the pulmonary artery. Results of the use of fibrinolysin]. PMID- 4223831 TI - Coagulation changes during experimental hemorrhagic shock. Clotting activity, contribution of splanchnic circulation and acidosis as controlled by THAM. PMID- 4223832 TI - Removal of impacted pulmonary emboli by retrograde injection of fibrinolysin into the pulmonary veins. Report of three cases and experimental studies. PMID- 4223833 TI - Laceration of abdominal aorta and study of intact abdominal wall as tamponade: report of survival and literature review. PMID- 4223834 TI - [Some problems of histochemistry of T.B. tubercles]. PMID- 4223835 TI - [Studies on the activity of galactokinase in the blood of normal persons and of patients with GDo trisomy]. PMID- 4223837 TI - [Amino acids in the blood in Huntington's chorea]. PMID- 4223836 TI - [Phenolic acids and indoles in the urine in Huntington's chorea]. PMID- 4223838 TI - [Lumbago-sciatica-renal carbuncle]. PMID- 4223839 TI - [The role of staphylococci of phage type 80 in the origin of surgical infections]. PMID- 4223840 TI - [The significance of catecholamines in the clinical picture of schizophrenia]. PMID- 4223841 TI - [Studies on the uptake of P 32 by erythrocytes in patients with schizophrenia and other psychoses]. PMID- 4223843 TI - [On the classification of psychopharmaca used in the treatment of depression]. PMID- 4223842 TI - [On the possibilities of psychiatric pharmacotherapy]. PMID- 4223844 TI - [Method for early evaluation of the clinical effect of antidepressive psychopharmaca]. PMID- 4223846 TI - [Lee effect (DAF, delayed auditory feedback) in experimental psychiatry. (Methodologic report)]. PMID- 4223845 TI - [The nosological place of the group of mixed psychoses. Differentiation from manic-depressive disorders and schizophrenia]. PMID- 4223847 TI - [Methodological contribution to the primary determination of the effect of psychotropic substances]. PMID- 4223848 TI - [Theses for a discussion on higher nervous activity]. PMID- 4223849 TI - [Schizophrenic and non-schizophrenic delusions]. PMID- 4223850 TI - [The problem of the so-called schizoid-autistic phenomena]. PMID- 4223851 TI - [Anamnestic data on patients with a diagnosis of schizophrenia]. PMID- 4223852 TI - [The endocrinologic factor in schizophrenia]. PMID- 4223853 TI - [The pseudoschizophrenic syndrome]. PMID- 4223854 TI - [The pseudoneurotic form of schizophrenia]. PMID- 4223855 TI - [Problems of differential diagnosis of schizophrenia and schizoid psychopathy]. PMID- 4223856 TI - [The problem of typologic differential diagnosis based on the disease course of schizophrenia and cyclophrenia]. PMID- 4223857 TI - [Morbid aggressivity in several schizophreniform psychoses]. PMID- 4223858 TI - [The pseudodementia-euphoric variant of schizophrenia]. PMID- 4223859 TI - [The difference between hallucinations of schizophrenic origin and those caused by experimental sensory deprivation]. PMID- 4223860 TI - [Schizophrenic defect or residual state]. PMID- 4223862 TI - [The relationship between the composition of blood proteins and the course of schizophrenia]. PMID- 4223861 TI - [Biochemical research trends and their positive value in the clinical diagnosis of schizophrenia]. PMID- 4223863 TI - [Combined estrogen-progestational hormone treatment of functional uterine bleeding. Contribution to the mechanism of the hemostatic effect of synthetic steroid hormones]. PMID- 4223864 TI - [The effect of ATP on some histochemical reactions of the skeletal and heart muscles]. PMID- 4223865 TI - The anti-seborrheic qualities of zinc pyrithione (zinc pyridine-2-thiol-1-oxide) in a cream vehicle. 1. A preliminary report. PMID- 4223866 TI - [Biochemical studies on the action mechanism of phenylbutazone and a few derivatives]. PMID- 4223867 TI - Water fluoridation--its effect on pedodontics. PMID- 4223868 TI - [Fluoride and mongolism]. PMID- 4223869 TI - Human relations in a pedodontic practice. PMID- 4223871 TI - Senior dental student recognition awards for 1966. PMID- 4223870 TI - Pain control: trigeminal neuralgia--a review of etiology and treatment. PMID- 4223873 TI - [Ultrasonics in dental technology]. PMID- 4223872 TI - [ATR, the nontraumatic crown and bridge procedure]. PMID- 4223874 TI - Handicapped children in dental practice. PMID- 4223875 TI - Job readiness: key to placement. PMID- 4223876 TI - [The skin ridges system (dermatoglyphics). An up to the present neglected identification complex in medicine]. PMID- 4223877 TI - [A significant increase of Tahyna virus neutralizing antibodies in patients with the clinical diagnosis of "acute febrile disease"]. PMID- 4223878 TI - Morphological and biochemical correlates of cerebral microsomes. II. A study of the structural association of glutamine synthetase, ATPase, and an esterase acting on o-nitrophenyl acetate. PMID- 4223879 TI - [The histochemistry of mucopolysaccharides in normal, chemically contracted and relaxed tendon fibres]. PMID- 4223881 TI - [Relation of respiratory insufficiency to heart enlargement in patients with chronic cor pulmonale]. PMID- 4223880 TI - An evaluation of 51 patients with hepatic artery infusion. PMID- 4223882 TI - [On the epidemiology of tick-borne encephalitis in a district center situated in southern Taiga of the Krasnoiarsk Region]. PMID- 4223883 TI - [Biology of the sclerosis process. XXIV. Topochemistry of mucopolysaccharides in the coronary arteries in children, correlated with changes of elastic tissue]. PMID- 4223885 TI - Myocardosis and cardiac failure in men. PMID- 4223884 TI - Vascular connective tissue under the influence of oestrogens. I. Biochemical and morphological studies of aortae of untreated female and male rabbits, and aortae of castrated and sham-operated female rabbits. PMID- 4223886 TI - [Vasil' Gavrilovich Ushakov (on the centennial of his birth)]. PMID- 4223887 TI - [The nosological place of the group of schizophrenias]. PMID- 4223888 TI - [Bacteriophage typing of staphylococci isolated in pediatric institutions]. PMID- 4223889 TI - Depression of afferent activity originating in muscle spindles induced by mephenesin, procaine and caramiphen. PMID- 4223890 TI - On urinary acid mucopolysaccharides in a case of gargoylism (Hurler's syndrome). A preliminary note. PMID- 4223891 TI - Studies on acid mucopolysaccharides in urine. 1. On urinary acid mucopolysaccharides from patients with mongolism (Down's syndrome). PMID- 4223892 TI - [Phlegmon of the J.L. Petit type and spontaneous external biliary fistulas. (Collective review and clinical case)]. PMID- 4223893 TI - A probable case of Dracunculus medinensis (Linnaeus, 1758) Gallandant, 1773, in a dog in Pennsylvania. PMID- 4223894 TI - Acid mucopolysaccharides and lipids of Japanese arteries, with special reference to the absence of hyaluronic acid in Japanese cerebral artery. PMID- 4223895 TI - [Thromboembolic complications following fractures]. PMID- 4223896 TI - [The mechanism of organic damage to the heart and the large vessels in blunt thoracic traumas]. PMID- 4223897 TI - [Treatment of a severe thoracic trauma. Avulsion of all rib cartilages left from the sternum by surgical fixation with 2 Krischner wires]. PMID- 4223898 TI - [Injuries of the great vessels as a complication of pelvic fractures]. PMID- 4223899 TI - [Echoencephalography and closed cerebrocranial injuries]. PMID- 4223900 TI - [Contribution to head contusion with a fatal outcome in childhood]. PMID- 4223901 TI - [Medical expert evaluation of abdominal wall hernias]. PMID- 4223902 TI - [A contribution to the problem of "acute hematogenous osteomyelitis and accidents"]. PMID- 4223903 TI - [Fatal varicose vein hemorrhage following dog-bite]. PMID- 4223904 TI - [Experimental studies on human contact sensitization to p-aminodiphenylamine and p-phenylenediamine]. PMID- 4223905 TI - [Hyperplasia glandularum sebacearum et adenosis sebacea eruptiva senilis profunda]. PMID- 4223906 TI - [Histochemical analysis of acid mucopolysaccharides in the epithelium of the seminal vesicles and gonads in the postembryonic stage]. PMID- 4223907 TI - Fluoridation's benefits not limited to health: some observations, some predictions. PMID- 4223908 TI - The preparation of some 4-substituted nicotinic acids and nicotinamides. PMID- 4223909 TI - Placental estrogen biosynthesis during human pregnancy. PMID- 4223910 TI - [The Medical Association demands: workmen's compensation for chief physicians and assistant chief physicians--a just claim]. PMID- 4223911 TI - [Myasthenia gravis]. PMID- 4223912 TI - Virus aetiology for Down's syndrome (mongolism). PMID- 4223913 TI - Arterial infusion chemotherapy of liver cancer. PMID- 4223914 TI - Diagnosis of retinal detachment. PMID- 4223915 TI - Management of cervical carcinoma in the elderly patient. PMID- 4223916 TI - Sunlight and skin. 3. Degenerative and neoplastic effects. PMID- 4223917 TI - Electrocardiogram of the month. PMID- 4223918 TI - Hearing measurement and hearing loss. PMID- 4223919 TI - University of Arkansas Medical Center. PMID- 4223920 TI - Colles' fractures. PMID- 4223921 TI - Acute and chronic intestinal obstruction: the development of current concepts of management. PMID- 4223922 TI - [Chronologic aspects of the anti-implantation effect of the presence of a thread in the uterus of the rat]. PMID- 4223923 TI - [Action of a tensioactive agent on pregnancy in rats]. PMID- 4223924 TI - [Study of the development of pulmonary adenomas in mice of various strains after treatment with urethan combined with x-rays]. PMID- 4223925 TI - [On the antimicrobial and anticancerous activity of a new antibiotic, rufochromomycin]. PMID- 4223926 TI - [Study, using the Allium test, of the antimitotic properties of rufochromomycin]. PMID- 4223927 TI - [On the excitability of the respiratory system to CO2 as a function of the oxygen contribution]. PMID- 4223928 TI - [Development of glycogen level of the heart during the fetal and neonatal life in rats]. PMID- 4223929 TI - [General characteristics of excitable artificial membranes]. PMID- 4223930 TI - [New technic for the synchronous recording of the blood flow and the electrical activity of the brain in awake animals]. PMID- 4223932 TI - [Research on the effects of soluble ribonucleic acid on the differentiation of the Paracentrotus lividus sea-urchin egg]. PMID- 4223931 TI - [Differences in N-acetylhistidine level in fresh water and sea water fish]. PMID- 4223934 TI - [AKR leukemogenesis after x-irradiation followed by restoration by allogenic fetal liver]. PMID- 4223933 TI - [Action of dehydroepiandrosterone on compensatory adrenal hypertrophy]. PMID- 4223935 TI - [Attempts at serotherapy of atypical T 8 epithelioma of Wistar rats]. PMID- 4223936 TI - [Study, using the Allium test, of the antimitotic properties of daunomycin]. PMID- 4223937 TI - [Acid phosphatase and lysosomes in hepatocytes in trypsinated culture]. PMID- 4223938 TI - [Research on the metabolism of sulfur. XIV. Metabolism of sulfur and nitrogen]. PMID- 4223939 TI - [Recent observations on the correlations between the cerebral flow and invading depression]. PMID- 4223940 TI - [On the activity of different nitrogen donors during the biosynthesis of purines in Escherichia coli B]. PMID- 4223941 TI - [Inhibition of reserpine postamphetamine hypertension by antidepressive substances of the imipramine group]. PMID- 4223942 TI - [Feminization of the adult male mouse by injection of estrogens into the pregnant mother]. PMID- 4223943 TI - [Some electroretinographic aspects of inhibition phenomena between the scotopic and photopic systems]. PMID- 4223944 TI - [Influence of total irradiation by x-rays on the thyroid metabolism of white rats]. PMID- 4223945 TI - [Effects of some lactones on the speed of exosmosis of pigments of Beta vulgaris (var. rubra)]. PMID- 4223946 TI - [Arterial anomalies in the chick embryo treated with alkaline ribonuclease]. PMID- 4223947 TI - [Volumetric and weight variation of the hypophyseal lobes of the male green frog during the annual cycle and growth]. PMID- 4223948 TI - [Increased resistance of F1 hybrids with regard to a second transplantation of parental isologous tumors presenting the phenomenon of syngenic preference]. PMID- 4223949 TI - [Blood pressure effect of occlusion of the primary carotids before and after anesthetic infiltartion of the carotid sinus in chloralosed dogs and rabbits]. PMID- 4223950 TI - [Effect of guanethidine on the metabolism of catecholamines in the hypertensive rat]. PMID- 4223952 TI - [1st study of the Hering Breuer inhibitory reflex in the intact or chemodenervated awake dog]. PMID- 4223951 TI - [Experimental acute hypercapnia in dogs. Variations of the acid-base equilibrium in the arterial blood and cerebrospinal fluid]. PMID- 4223953 TI - [Study by immunofluorescence of gastric antimucosa auto-antibodies in man]. PMID- 4223954 TI - [Study of the action of triiodothyroacetic acid on resistance to acute anoxia]. PMID- 4223955 TI - [Further observations concerning the carbonated nutrition of retinolytic bacteria]. PMID- 4223956 TI - [Effect of K+ ions on the "spontaneous" activity of the 6th abdominal ganglion of the cockroach Periplaneta americana]. PMID- 4223957 TI - [Study, by the homotransplantation of the neonatal rat testis in the testis of the mature rat, of the factors of spermatogenic development before maturity and the factors of involution of the seminal issue in the testis deprived of excretory ducts]. PMID- 4223958 TI - [Ultrastructural translation of glycolipid storgae phenomena in Gaucher's disease]. PMID- 4223959 TI - [Ultrastructural changes of the kidney in hypothyroid rats]. PMID- 4223960 TI - [Morphology of the autotransplanted kidney in the iliac fossa in dogs]. PMID- 4223961 TI - [Influence of fasting on the components of the gastric juice in rabbits]. PMID- 4223962 TI - [Observations on the re-innervation of neuromuscular spindles in cats]. PMID- 4223963 TI - [Quantitative study of the attractive power of the odor of liquid manure for Eristales tenax (Diptera, Syrphida) larvae and adults]. PMID- 4223964 TI - [Hemoglobin level and importance of the hematocrit in diploid and triploid individuals of the salamander Pleurodeles waltlii]. PMID- 4223965 TI - [Comparative activity of the antidiuretic hormone in Bufo marinus L. and Bufo alvarius Girard]. PMID- 4223966 TI - [Effects of colchicine on the synthesis of nuclear proteins and desoxyribonucleic acids in fibroblasts cultivated in vitro]. PMID- 4223968 TI - [Behavior of the human voice during an auditory binaural stimulation. Electroglottographic study]. PMID- 4223967 TI - [Development of factors of hemostasis after perfusion of hemolysate in rabbits. Influence of heparin]. PMID- 4223969 TI - [Influence of calcium and strontium ions on the efflux of potassium at the level of the papillary muscle in cats]. PMID- 4223970 TI - [Tactile sensitivity of the hand in normal adult subjects: quantitative study with Weber's compass]. PMID- 4223971 TI - [Attempt at production of immunologic paralysis and facilitation in adult dogs]. PMID- 4223972 TI - Dental care for the homebound aged patient. PMID- 4223974 TI - [Child care centers and the practical aspects of management of the handicapped]. PMID- 4223973 TI - [Treatment of intestinal amebiasis with chlorohydroxiquinoline]. PMID- 4223975 TI - [Experience in the work of the hygiene department of a medical institution]. PMID- 4223976 TI - [The Folke Bernadotte home]. PMID- 4223977 TI - Vitamin C-induced increase of dermatan sulfate in cultured Hurler's fibroblasts. AB - In fibroblasts taken from patients witli Hurler's syndromne and grown in cultlure, dermatan sulfate constituted a larger percentage of the total sulfated glycosaminoglycans than it did in cultured fibroblasts from unaffected individuals. Moreover, the addition of ascorbic acid (vitamnin C) to the culture medium markedly increased the concentration of dermatan sulfate in the Hurler's fibroblasts but not in the normal fibroblasts. The biochemical phenotype of the Hurler's cells persisted during 28 weeks of serial culture. PMID- 4223978 TI - Work and heart disease in Wisconsin. I. Medical basis for workmen's compensation awards over ten years. PMID- 4223979 TI - Acid mucopolysaccharide and hexosamine metabolism in dermal connective tissue of adrenalectomized rats. PMID- 4223980 TI - Differences in variability of discharge frequency between primary and secondary muscle spindle afferent endings of the cat. PMID- 4223981 TI - DNA synthesis and differentiation in embryonic kidney mesenchyme in vitro. AB - Mitosis accompanies the differentiation of embryonic metanephrogenic mesenchyme in vitro. Inhibition of mitosis by 5-fluorodeoxyuridine, but not by x-rays, is associated with inhibition of differentiation. The difference may be due to the effect of 5-fluorode-oxyuridine on DNA synthesis. PMID- 4223982 TI - The effect of restraint on the content of acid polysaccharides of glandular gastric wall in rat. PMID- 4223983 TI - [Sanitary and hygienic working conditions and the state of health of hide scourers at astrakhan processing factories in central Asia and Kazakhstan]. PMID- 4223984 TI - Case records of the Massachusetts General Hospital. Case 40-1966. PMID- 4223985 TI - [Behavior of the fibrinolytic factors during preservation of blood transfusion material]. PMID- 4223986 TI - Combined mongolism and leukemia. Report of eight cases with chromosome studies. PMID- 4223987 TI - Normal-21-trisomy mosaicism. Report of four cases and review of the subject. PMID- 4223988 TI - [The diagnosis of papyraceous auricle]. PMID- 4223989 TI - [Further observations on the inhibition of aldosterone, on the acclimitation to heat, in white rats]. PMID- 4223990 TI - [Muscular exercise at altitude: measurement of dynamic ventilatory work]. PMID- 4223991 TI - [Free amino acid "pools" in tissues of normal rats]. PMID- 4223992 TI - [Precipitation of calcium in tegumentary calciphylaxis in rats and its spectrographic evaluation]. PMID- 4223993 TI - [Comparative study of some properties of the sodium salt of N-acetyl-amino-6 hexanoic acid and epsilon-aminocaproic acid]. PMID- 4223994 TI - [Presence of extra- and intranuclear annulated membranes during natural and experimental ovogenesis in Nereis pelagica L. (Annelida, Polycheta)]. PMID- 4223995 TI - [Mediastinal lymphoma of Swiss mice receiving urethane. V. Systematic morphologic study with the electron microscope of intracellular virus particles]. PMID- 4223996 TI - [Karyometric study of the infundibular wall in normal and castrated male guinea pigs]. PMID- 4223997 TI - [Histoenzymologic study of the hypothalamus of guinea pigs. I. Research on the variations of acetylcholinesterase during the estrus cycle]. PMID- 4223998 TI - [Reciprocal influences of glucose, pyruvate and lactate on their oxidation in neoplastic cells]. PMID- 4223999 TI - [Effects of hypervitaminosis E on the testis of the golden hamster]. PMID- 4224000 TI - [Influence of L-lysine on the transport of glucose across an isolated fragment of rat small intestine]. PMID- 4224001 TI - [Intestinal ulceration during restraint in rats]. PMID- 4224002 TI - [Effects of sympatholytic substances on the spontaneous diuresis of the normal kidney and the nerveless kidney in awake dogs]. PMID- 4224003 TI - [Perturbations of the automatism of the isolated snail ventricle perfused by mineral solutions and their relationships with the respiratory exchanges of tissue]. PMID- 4224004 TI - [On the role of adrenal cortex hormones in the theramogenesis of shivers in dogs]. PMID- 4224005 TI - [Reinforcement, by a contribution of substrates, of the thermogenetic effect of catecholamines in the fight against cold]. PMID- 4224006 TI - [Maternal behavior induced in adult castrated rats]. PMID- 4224007 TI - [Water and alcohol consumption of mice sensitive or refractory to audiogenic crises]. PMID- 4224008 TI - [On the level of free methionine and B 12 of human blood serum]. PMID- 4224009 TI - [Action of some inhibitors and substrates of DOPA-carboxylase on the in vitro decarboxylation of 5-hydroxytryptophan by nervous tissue of the mollusc Helix pomatia]. PMID- 4224010 TI - [Hepatic insufficiency and neurotropic medicinal activity]. PMID- 4224011 TI - [Suppression by shock of vasodilator reactions to adrenalin]. PMID- 4224012 TI - [Change by shock of the influence of catecholamines on the cardiac flow]. PMID- 4224013 TI - [Bradycardia of the apneic diver]. PMID- 4224014 TI - [Favorable effect of relative hypothermia on the development of the disease of the newborn mouse, inoculated with a "warm variant" of Coxsackie virus]. PMID- 4224015 TI - [Tumors induced in RAP mice by inoculation of human lymphosarcoma powder]. PMID- 4224016 TI - [Ultrastructure of a mammary tumor of mice induced by injection of human lymphosarcoma]. PMID- 4224017 TI - [Cytology of the distal lobe of the hypophyso-pituitary complex of Varanus ex. exanthematicus (Bosc) and of Varanus n. niloticus (Linne)]. PMID- 4224018 TI - [Physiologic actions of insulin and zinc on the electric membrane phenomena of skeletal muscular fiber]. PMID- 4224019 TI - [Oxygen consumption of the isolated rat duodenum. Its different orders of variation]. PMID- 4224020 TI - [Study of mucopolysaccharides of rat bone during experimental osteolathyrism]. PMID- 4224021 TI - [In vitro metabolism of 5-hydroxytryptamine in the adrenal glands of rats]. PMID- 4224022 TI - [Study of the peptidase activity of the pineal gland of pigs]. PMID- 4224023 TI - [Effects of ablation of the olfactory bulbs on the genital physiology in adult rabbits]. PMID- 4224024 TI - [Loss of olfactory afferents and interspecific aggression in rats]. PMID- 4224025 TI - [Action of ascorbic acid on ammonemia, especially in cirrhotics]. PMID- 4224026 TI - [Relative biological efficiency of fission neutrons in total body irradiation of mice]. PMID- 4224027 TI - [Protective effect of cystamine on the inhibition by X rays of compensatory renal hyperplasia]. PMID- 4224028 TI - [Preventive antigen of Pseudomonas aeruginosa. I. Localization of the antigen in the bacterial cell]. PMID- 4224029 TI - Nature and significance of changes in the houseparent role in institutions for children. PMID- 4224030 TI - [Pediatric rehabilitation]. PMID- 4224032 TI - [The adhesiveness of stromas, red cell fragments and stroma fragments]. PMID- 4224031 TI - [Hematopoietic cell strains]. PMID- 4224034 TI - [Nomenclature of genetic factors supported by human immunoglobulins]. PMID- 4224033 TI - [Study of plasmocytopoiesis. II. Probable scheme of the means of formation of plasmocytes elaborated from the results of the numeration of their mitoses]. PMID- 4224035 TI - [Robert Feissly (1884-1965)]. PMID- 4224036 TI - [Myelosclerosis associated with medullary aplasia]. PMID- 4224037 TI - [Maternal thrombopenia. Neonatal thrombopenia treated by exchange transfusion]. PMID- 4224038 TI - [Chronic erythroblastopenia. Therapeutic effect of androgens]. PMID- 4224039 TI - [Secondary anemia of the hemolytic disease of the newborn related to feto maternal ABO incompatibility]. PMID- 4224040 TI - [Comparative hematology of the Amerindian populations of Bolivia and adaptive phenomena]. PMID- 4224041 TI - [Studies on anemia of cirrhosis. IV. A possible mechanism of the erythrocytic reduced glutathione deficit]. PMID- 4224042 TI - [Studies on anemia of cirrhosis. V. Demonstration of an anomaly of erythrocytic lipids]. PMID- 4224043 TI - [Studies on anemia of cirrhosis. VI. Total anaerobic glycolysis and ATP]. PMID- 4224044 TI - [Quantitative study of the "I" antigen in erythrocytes of patients suffering from acute leukemia]. PMID- 4224045 TI - [Examination of the lymph during chronic lymphoid leukemia. (Preliminary study)]. PMID- 4224046 TI - [Anomalies of hemostasis in thrombocythemia]. PMID- 4224047 TI - [Contemporary mononucleosis syndrome at the beginning of the remission of acute leukemia]. PMID- 4224048 TI - [Macrophage histiocytes in the circulating blood]. PMID- 4224049 TI - Diagnostic significance of atrial fibrillatory waves. PMID- 4224050 TI - The thrombolytic therapy of acute myocardial infarction. PMID- 4224051 TI - Dental problems in children. PMID- 4224052 TI - [The sheath of the M. rectus abdominis of the dog]. PMID- 4224053 TI - New Zealand's external aid in dental health. PMID- 4224055 TI - Diagnosis and treatment of low back pain with emphasis on the herniated disc. PMID- 4224054 TI - [Semi-quantitative study of the metabolism of sulfate mucopolysaccharides in the cervical cells of the guinea pig]. PMID- 4224056 TI - Mucopolysaccharide from patients with cystic fibrosis of the pancreas. AB - Physical and immunologic methods were used to demonstrate the presence of an apparently unique glycoprotein in stool and tissue of patients having cystic fibrosis of the pancreas. The detection of a molecular structure specific for the disease is consistent with the apparent hereditary nature of the affection. PMID- 4224057 TI - The epidemiology of gingivitis in children. PMID- 4224058 TI - The fibrinolytic enzyme system in cervical mucus. PMID- 4224059 TI - Understanding backache, tension and fatigue. PMID- 4224060 TI - Reaction of rabbit leucocytes to staphylococcal (Panton-Valentine) leucocidin in vivo. PMID- 4224061 TI - Some observations on the caseinolytic properties of a purified, activator-free, porcine plasmin preparation. PMID- 4224062 TI - The influence of time upon the inhibition of plasmin by normal, human serum. PMID- 4224063 TI - Studies on the inhibition of plasmin caseinolysis by human serum and a method for the assay of inhibiting activity. PMID- 4224064 TI - [What's news?]. PMID- 4224065 TI - [ATR, the non traumatic crown and bridge system]. PMID- 4224066 TI - [Apparatus for the composition of free end dentures--an aid for the technician]. PMID- 4224068 TI - Studies on glycolysis of red blood cells in anemias. I. Congenital microspherocytosis. PMID- 4224067 TI - Urinary amino acid excretion in mongolism. PMID- 4224069 TI - [On structural binding and secretion of catecholamines. Histochemical and pharmacological studies with the electron microscope]. PMID- 4224070 TI - The effect of premedication with chlorpheniramine on reactions to methylglucamine iodipamide. PMID- 4224071 TI - Translocation mongolism. PMID- 4224072 TI - Mucopolysaccharide excretion in patients with Hurler's syndrome, their families, and normal man. PMID- 4224073 TI - [Agensia of permanent teeth in Down's syndrome (mongolism)]. PMID- 4224074 TI - Pharmacologic properties of bis-quaternary ammonium derivatives of m- and p- di (2-aminopropyl)-benzene. PMID- 4224075 TI - Rosacea and acne. PMID- 4224076 TI - On the biosynthesis of testicular steroids in vitro and its inhibition. PMID- 4224077 TI - Histochemical identification of acid mucopolysaccharides in cat lingual glands. PMID- 4224078 TI - The proteolytic activity of citrated stored blood and some proteins of the clotting system. PMID- 4224079 TI - A fossil human bone from Anatolia. PMID- 4224080 TI - Some factors of human gait. PMID- 4224081 TI - Palmar dermatoglyphics of the Dogon and Peul of Mali. PMID- 4224082 TI - Nucleic acid synthesis in x-irradiated thymocytes. PMID- 4224083 TI - Treatment of seborrheic dermatitis in the Negro scalp. PMID- 4224084 TI - Successful total correction of ventricular septal defect, diverticulum of the left ventricle, and anomaly of the thoracoabdominal wall in an 11-year-old boy with cardiac dextroversion. PMID- 4224085 TI - Bacteriophage typing of Staphylococcus aureus using a single concentration of phage (100 x RTD). PMID- 4224086 TI - Physicians, dentists, and children. PMID- 4224087 TI - Repression and the control of cyclic enzyme synthesis in Bacillus subtilis. PMID- 4224088 TI - [Combined treatment of patients with chronic gastritis with the mineral water "Sanapiro"]. PMID- 4224089 TI - Histoenzymatic reactions in experimental lead poisoning in rabbits. PMID- 4224090 TI - [Analytical differentiation of purine and pyrimidine nucleotides. I. Determination of AMP, ADP and ATP, and of GTP + ITP]. PMID- 4224091 TI - Swelling and shrinkage phenomena in liver mitochondria. V. Permeability of the mitochondrial membrane to univalent cations: effect of Mg++. PMID- 4224092 TI - Interaction of streptokinase and human plasminogen. 3. Plasmin and activator activities in reaction mixtures of streptokinase and human plasminogen or human plasmin of various molar ratios. PMID- 4224093 TI - Urokinase levels in urine after nicotinic acid injection. PMID- 4224094 TI - Comparison of caseinolytic and fibrinolytic assays for plasmin (fibrinolysin) in "fibrinolytic agents". PMID- 4224095 TI - The fine structure of nuclei as revealed by electron microscopy. 3. Adenosine triphosphatase activity in the pores of nuclear envelope of mouse choroid plexus epithelial cells. PMID- 4224096 TI - Electrocardiographic and vectorcardiographic signs of left and right ventricular hypertrophy in endurance athletes. PMID- 4224097 TI - [Centenary of Victor Morax (1866-1935)]. PMID- 4224098 TI - [Treatment of strabismus in the free space]. PMID- 4224100 TI - [Prognostic value of certain etiologic and clinical characteristics during detachment of the retina]. PMID- 4224099 TI - [Study of the influence of abnormal visual sensory relationships as a function of the age at which strabismus occurs]. PMID- 4224101 TI - [Apropos of dermoid cysts of the orbit]. PMID- 4224102 TI - [Aspects of the fine structure of the connective tissue in certain cicatricial states of the corneal stroma]. PMID- 4224103 TI - [The optical correction of aphakics]. PMID- 4224104 TI - [Glaucoma]. PMID- 4224105 TI - [Stiffback complaints of pole vaulters]. PMID- 4224106 TI - Glenrose . . . Canada's unique school-hospital. PMID- 4224107 TI - Changes in reactivity of the heart to sympathetic and parasympathetic influences during prolonged compensatory hyperfunction. PMID- 4224108 TI - Indices of blood gases compared in healthy persons and heart patients in the Tashkent climate. PMID- 4224109 TI - Epidemiologic efficacy of live influenza vaccine during 1962 outbreaks of influenza A2 and B. PMID- 4224110 TI - Presence of sodium-potassium-stimulated ATPase in boar epididymal spermatozoon. PMID- 4224111 TI - Histochemical demonstration of sodium-potassium-activated adenosinetriphosphatase in normal and leukaemic granulocytes. PMID- 4224112 TI - Histoenzymatic studies on the behavior of succinic acid dehydrogenase, NADH2 tetrazolium reductase, ATP-ase and alkaline phosphatase in cancer of the uterine cervix in women. PMID- 4224114 TI - Arabic historiography as related to the health professions in medieval Islam. PMID- 4224113 TI - [Rene Descartes and the theory of life phenomena]. PMID- 4224115 TI - [K. E. von Baer as a craniologist and the 1861 meeting of anthropologists in Goettingen]. PMID- 4224116 TI - [2 unknown letters of the surgeon Heinrich von Pfalzpaint from the year 1453]. PMID- 4224117 TI - [Virchow in Hohenleuben]. PMID- 4224119 TI - Low back pain etiology and pathogenesis. PMID- 4224118 TI - [A newly found manuscript dealing with Lebenstein's treatise 'Of the burned waters']. PMID- 4224120 TI - The etiology and pathogenesis of pain of spinal origin. PMID- 4224121 TI - Emotion and low back pain. PMID- 4224122 TI - The compensation back. PMID- 4224123 TI - Management of low back pain--the examination. PMID- 4224124 TI - Results in surgical treatment of herniated lumbar intervertebral discs: investigation of the late results in subjects with and without supplementary spinal fusion--a preliminary report. PMID- 4224125 TI - [Diseases of the follicular system in the trichlorphenol industry]. PMID- 4224126 TI - [5-year experience of the work of the department of occupational skin diseases]. PMID- 4224127 TI - [Lumbago, backache and muscle relaxants. (Thoughts on disk physiopathology)]. PMID- 4224128 TI - [Considerations on the histogenesis of thymus lymphomas induced by general irradiation by means of x-rays in mice of various lines]. PMID- 4224129 TI - [Ablation of the olfactory bulbs in the immature rabbit. Repercussions on the genital tract and sexual behavior]. PMID- 4224130 TI - [A case of occupational toxicodermia caused by 2, 3, 5, 6 tetrachloronitrolozene]. PMID- 4224131 TI - Macular dystrophy of the cornea. A histochemical and electron microscopic study. PMID- 4224132 TI - Amiphenazole sensitivity with oral ulceration. PMID- 4224133 TI - Possible genetic consequences of family planning. PMID- 4224134 TI - Low back pain. PMID- 4224136 TI - Fungi in nails. PMID- 4224135 TI - A new type of spatial vectorcardiograph. PMID- 4224137 TI - Management of disorders of the nails. PMID- 4224139 TI - Hunter-Hurler Syndrome: clinical and biochemical study. Combined clinical staff conference at th National Institutes of Health. PMID- 4224138 TI - Glycoprotein and collagen metabolism in the dermis of hypophysectomized rats. PMID- 4224140 TI - [Medical problems in the surgical treatment of mitralic heart disease]. PMID- 4224141 TI - [A method of Girard's for finding total number roots of square and cubic equations]. PMID- 4224142 TI - [The significance of bacteriophage typing method in the epidemiology of staphylococcal diseases. (Review of the literature)]. PMID- 4224143 TI - Eczematous dermatitis produced by airborne molds. PMID- 4224144 TI - Effect of pH on the kinetics of frog muscle phosphofructokinase. PMID- 4224145 TI - A genetical study of Hirschsprung's disease; congenital intestinal aganglionosis. PMID- 4224146 TI - Pathogenesis of urolithiasis: relation of urinary fibrinolytic activity to nondialyzable urinary solids. PMID- 4224147 TI - Characterization of fibrinolytic activity of vascular intima. PMID- 4224148 TI - Control of glycolysis in human erythrocytes by inorganic phosphate and sulfate. PMID- 4224149 TI - Effects of acetylcholine infused into renal artery of dogs. PMID- 4224150 TI - Familial non-progressive myopathy with muscle cramps after exercise. A new disease associated with cores in the muscle fibres. PMID- 4224151 TI - Formation of estrogens by hydatidiform moles in vitro. PMID- 4224152 TI - Staphylococcus aureus strains in the "52, 52A, 80, 81 complex". PMID- 4224153 TI - Industrial dermatitis. PMID- 4224154 TI - Legal aspects of accidents. PMID- 4224155 TI - Thoughts on the accessibility of places of work to disabled employees and clients. PMID- 4224156 TI - [Change in the shape and size of actomyosin particles of striated muscles in ontogenesis]. PMID- 4224157 TI - Maternal transmission of a 21/1 translocation associated with Down's syndrome. PMID- 4224158 TI - Urinary tetrahydrocortisone and tetrahydrocortisol in infants born of mothers treated with corticosteroids during pregnancy. PMID- 4224159 TI - The renal excretion of ethylenediaminetetraacetate in the dog. PMID- 4224160 TI - Skin sensitivity to phenindione. Report of a case. PMID- 4224161 TI - [On Obrinski's multiple malformative syndrome. (Clinical and anatomo-pathological study)]. PMID- 4224162 TI - [Peculiarities of the clinical course of toxic kidney disease]. PMID- 4224164 TI - Herpetic whitlow. PMID- 4224163 TI - Aldosterone and oxidative phosphorylation in liver mitochondria. PMID- 4224165 TI - Changes in the amount of urinary androgen hormones in students during intensive intellectual work. PMID- 4224166 TI - Effect of tetracyclines and chloramphenicol on biosynthesis in vitro. (Immunologic and histochemical studies). PMID- 4224167 TI - Ultra-low frequency acceleration ballistocardiogram in experimentally induced myocarditis. PMID- 4224169 TI - Changes in blood glucose level induced by repeated streptococcal infections. PMID- 4224168 TI - Methionine S35 biosynthesis under conditions of different functional strain and varying severity of the streptococcal inflammatory process. PMID- 4224170 TI - Changes in serum transaminases and lactate-dehydrogenase in experimentally induced myocarditis in dogs. PMID- 4224171 TI - Transaminase activity and destructive-proliferative changes. (Experimental study). PMID- 4224172 TI - Comparative studies of OT and RT23 tuberculin. PMID- 4224173 TI - Comparative studies of Monrad and Mantoux tests. PMID- 4224174 TI - Effect of serotonine on circulation. PMID- 4224175 TI - The effect of spinal injury on employment in a heavy industry. PMID- 4224176 TI - A clinical trial of rotational manipulation of the spine in back pain cases occurring in a factory. PMID- 4224177 TI - Thin-layer gel filtration of proteins and mucopolysaccharides. PMID- 4224178 TI - Adrenal secretion rates of C-19 and C-21 steroids before and after hypophysectomy in the pig and the dog. PMID- 4224179 TI - The bacteriology of the gingival crevices of erupting human incisors. PMID- 4224180 TI - Local factors of resistance in the gingival area. PMID- 4224181 TI - Experimental gingivitis in man. II. A longitudinal clinical and bacteriological investigation. PMID- 4224182 TI - Oxidative enzyme activities in keratinizing and non-keratinizing epithelium of normal and inflamed gingiva. PMID- 4224183 TI - The vascular supply of the periodontal membrane. An investigation of the number and size of perforations in the alveolar wall. PMID- 4224184 TI - Function of epithelial rests as suggested by their ultrastructure. PMID- 4224185 TI - Condylar adaptation to a change in intermaxillary relationship. PMID- 4224186 TI - Current titles in periodontology. PMID- 4224187 TI - Holidays for the disabled. PMID- 4224188 TI - [Experimental study in rabbits of various conservative interventions proposed in the treatment of coxarthrosis]. PMID- 4224189 TI - [Fractures of the acromial extremity of the clavicle]. PMID- 4224190 TI - [Trochanteral fractures]. PMID- 4224191 TI - [Principles of examination of a cerebral palsy invalid]. PMID- 4224192 TI - [Dissolution of a bony callus caused by battery effect during osteosynthesis]. PMID- 4224193 TI - [Apropos of the treatment of obstetrical paralyses of the brachial plexus: disinsertion of the sub-scapular without casulotomy]. PMID- 4224195 TI - [Handicapped children in normal classes]. PMID- 4224194 TI - [Case studies on mentally deficient children. 4. Mongolism]. PMID- 4224197 TI - [The treatment and prevention of ordinary rosacea]. PMID- 4224196 TI - Use of nicotinic acid and/or nicotinamide in high doses to treat schizophrenia. PMID- 4224198 TI - The Women's Memorial of World War I. PMID- 4224200 TI - Making able the disabled. PMID- 4224199 TI - Palpation of umbilical cord through abdominal wall. PMID- 4224201 TI - Sezary's reticulosis progressing to poikilodermia and mycosis fungoides. PMID- 4224202 TI - [Conditions of the mouth and teeth in children]. PMID- 4224203 TI - A bioassay of treatment of hemorrhagic shock. 3. Effects of a saline solution, ascorbic acid, and nicotinamide upon the toxicity of endotoxin for rats. PMID- 4224204 TI - General anaesthesia for children's dentistry. PMID- 4224205 TI - [Action of serotonin on the heart rate and the pulmonary blood mass in anesthetized dogs]. PMID- 4224206 TI - Walker carcinosarcoma 256 in study of anticancer agents. II. Results. PMID- 4224207 TI - Studies on the egg-membrane lysin of Tegula pfeifferi: isolation and chemical analysis of the egg membrane. PMID- 4224208 TI - Phospholipid involvement in gastric microsomal ATPase. PMID- 4224209 TI - [Acrodermatitis chronica atrophicans resembling skin manifestations following chronic arsenic poisoning]. PMID- 4224211 TI - Lysogenic properties of various Staphylococcus aureus phage-types. PMID- 4224210 TI - Participation of thymus in acid mucopolysaccharide metabolism. PMID- 4224212 TI - Industrial dermatitis--its detection and control. PMID- 4224213 TI - Pesticide exposure from concentrate spraying. PMID- 4224214 TI - Human effects of chronic, low dose radiation. Implications for adjudication of compensation claims for radiation injury. PMID- 4224215 TI - Practical pointers on managing disabled patients. PMID- 4224216 TI - Goblet cell fine structure. PMID- 4224217 TI - [Experiences with a new acne therapy. An example of the significance of the so called principles in modern external therapy]. PMID- 4224218 TI - Genetic recombination between alpha-toxin mutants of Staphylococcus aureus. AB - McClatchy, J. K. (The University of Texas Southwestern Medical School, Dallas), and E. D. Rosenblum. Genetic recombination between alpha-toxin mutants of Staphylococcus aureus. J. Bacteriol. 92:580-583. 1966.-A demonstration of genetic recombination between Staphylococcus aureus nonhemolytic mutants was attempted by means of transduction. The results of two-point reciprocal transductions placed the mutants into two genetic groups. Recombination within each group was not detectable within the limits of the method, but hemolytic recombinants were obtained in transductional crosses when donor and recipient were from different groups. At least two genetic loci are therefore involved in alpha-toxin production. The 11 mutants of group II were fibrinolysin-negative. The recombinants were always found to be restored to fibrinolysin production as well as to alpha-toxin production. These data suggest the existence of a pleiotropic gene simultaneously affecting the synthesis of both alpha toxin and fibrinolysin. The nine mutants of group I were fibrinolysin-positive. Group I members are postulated to be alpha-toxin structural mutants. Three mutants were also negative for bound coagulase, but no linkage was observed between the locus controlling bound coagulase and the loci for either fibrinolysin or alpha-toxin production. PMID- 4224220 TI - Use of tetrazolium for improved resolution of bacteriophage plaques. PMID- 4224219 TI - Adenosine triphosphatase activity of mycoplasma membranes. AB - Rottem, Shlomo (Hebrew University, Jerusalem, Israel), and Shmuel Razin. Adenosine triphosphatase activity of mycoplasma membranes. J. Bacteriol. 92:714 722. 1966.-Adenosine triphosphatase activity of Mycoplasma laidlawii, M. gallisepticum, and Mycoplasma sp. strain 14 was confined to the cell membrane. The enzymatic activity was dependent on magnesium, but was not activated by sodium and potassium. Ouabain did not inhibit the adenosine triphosphatase activity of the mycoplasmas, and did not interfere with the active accumulation of potassium by M. laidlawii cells. Sulfhydryl-blocking reagents and fluoride inhibited the enzymatic activity, whereas 2,4-dinitrophenol was without any effect. Membranes of M. laidlawii hydrolyzed other nucleotide triphosphates and adenosine diphosphate (ADP), but at a lower rate than adenosine triphosphate (ATP). Nucleoside-2'-(3')-phosphates, ribose-5-phosphate, glucose-6-phosphate, and pyrophosphate were not hydrolyzed by the membrane preparations. It seems that the enzyme(s) involved in ATP hydrolysis by M. laidlawii membranes is strongly bound to the membrane subunits, which would account for the failure to purify the enzyme by protein fractionation techniques. The adenosine triphosphatase activity of mycoplasma membranes resembles in its properties that of similar enzymes studied in bacteria. The mycoplasma enzyme(s) seems to differ from the adenosine triphosphatase associated with ion transport in mammalian cell membranes and from mitochondrial adenosine triphosphatase. PMID- 4224221 TI - Fine structure of spongy degeneration of the central nervous system (van Bogaert and Bertrand type). PMID- 4224222 TI - Heart disease and employment. The perspective of the occupational physician. PMID- 4224223 TI - Employers' liability for lunch-hour injury. PMID- 4224224 TI - Administration of the antimetabolite 6AN (6-aminonicotinamide) to horses. PMID- 4224225 TI - [Problems of industrial hygiene in the use of higher aliphate amines in potassium industry]. PMID- 4224226 TI - Nervous control of the mechanical properties of the abdominal wall at feeding in Rhodnius. PMID- 4224228 TI - Unwanted effects of propranolol. PMID- 4224227 TI - [Microbiological characterization of Cherepovez reservoir during the 1st year of its filling]. PMID- 4224229 TI - Comparative placental steroid synthesis. I. Conversion of (7-3-H) dehydroepiandrosterone to (3-H)-androst-4-ene-3,17-dione. PMID- 4224230 TI - [Practical advice concerning dental treatment of children]. PMID- 4224231 TI - [Data characterizing nonhospital medical care of the urban population]. PMID- 4224232 TI - [Cardiovascular diseases as a cause of disability of workers and white-collar employees in Krasnodar]. PMID- 4224233 TI - [Some problems in the work of the organizational methods office in a central district hospital]. PMID- 4224234 TI - [From the experience of the organization of first aid in poisoning]. PMID- 4224235 TI - [Work experience of the Regional Health Department of Voronezh in preventive examinations by midwives of women in rural areas]. PMID- 4224238 TI - [On the work of the central methodological commission in a medical institute]. PMID- 4224237 TI - [Organization of methodological education work in medical institutes]. PMID- 4224239 TI - [An important medical problem]. PMID- 4224236 TI - [Work experience of a voluntary public health unit of a regional newspaper]. PMID- 4224240 TI - Catabolic metabolism of cholesterol in stomach cancer. PMID- 4224241 TI - Histochemical studies of hydrolytic and oxidative enzymes in the human intestinal tumors. PMID- 4224242 TI - Cardiac output in erythrodermic skin disease. PMID- 4224243 TI - Influences of metabolic-effective agents on nucleotide systems in ocular tissues. PMID- 4224244 TI - Exchanges of nucleotide phosphates in normal and in failing canine hearts. PMID- 4224245 TI - Cutaneous atrophy secondary to intra-articular corticosteroid administration. PMID- 4224246 TI - Developmental highlights. PMID- 4224247 TI - The severely involved child: maternal backache. PMID- 4224248 TI - Emotional factors in residential care of handicapped children. PMID- 4224249 TI - Characterization of leukocyte glucose-6-phosphate dehydrogenase in normal and mutant human subjects. PMID- 4224250 TI - The excretion of nondialyzable urinary mucopolysaccharide in rheumatic and other systemic disease states. PMID- 4224251 TI - Elephantiasis nostras of the abdominal wall. PMID- 4224252 TI - [The phenomenon of Brucella phage absorption by chemical Brucella substrate]. PMID- 4224253 TI - Mucopolysaccharidosis type 3. Morphologic and biochemical studies of two siblings with Sanfilippo syndrome. PMID- 4224254 TI - The sex chromosomes in evolution and in medicine. AB - The recent emergence of human cytogenetics has a firm foundation in studies on other forms of life. Historical highlights are Mendel's studies on the garden pea (published in 1865 but lost in an obscure journal until 1900); formulation of cytogenic postulates by Sutton and Boveri (1902-1903); Bridges' discovery of chromosome abnormalities in Drosophila (1916), followed by numerous similar studies in plants; and demonstration of the chromosomal basis of the syndromes of Down, Klinefelter and Turner in man (1959).The sex chromosomes (XX and XY) evolved from a pair of undifferentiated autosomes of a premammalian ancestor, the X chromosome changing less than the Y as they evolved. Eleven numerical abnormalities of the sex chromosomes are known in man, and knowledge of their effects on development is accumulating. The abnormal complexes range in size from the XO error of Turner's syndrome to the XXXXY error of a variant of Klinefelter's syndrome. PMID- 4224255 TI - Case records of the Massachusetts General Hospital. Case 54-1966. PMID- 4224256 TI - LH and adrenal androgenesis. PMID- 4224257 TI - National Employ the Physically Handicapped Week: when America listens. PMID- 4224258 TI - Hire the Handicapped Week: a critique. PMID- 4224259 TI - [Scope of indication and therapeutic value of combined forms of use of flumethasone pivalate and the antimicrobial agent vioform]. PMID- 4224260 TI - [Brucke's modified transversostomy in the treatment of rectal stenosis and rectovaginal fistula]. PMID- 4224261 TI - [Compensation for bodily injury in various jurisdictions]. PMID- 4224262 TI - [On surgery of major incisional hernias of the anterior abdominal wall]. PMID- 4224263 TI - Neutral steroid sulphation and oestrogen biosynthesis in vitro by a feminizing Leydig cell tumour of the testis. PMID- 4224264 TI - Definitive surgical treatment of anomalous origin of left coronary artery from pulmonary artery: indications and results. PMID- 4224265 TI - Nonphosphorylating respiration of mitochondria from brown adipose tissue of rats. AB - Mitochondria from brown adipose tissue of cold-acclimated rats (6 degrees C) oxidize alpha-ketoglutarate at a rate twice that of controls (26 degrees C). In both groups, however, the phosphorus: oxygen ratio with alpha-ketoglutarate never exceeded unity, and it is essentially zero with either succinate or alpha glycerophosphate. Adenosine triphosphatase activity of these mitochondria is very low and it is not stimulated by 2,4-dinitrophenol. In addition, both respiration and phosphorylation are unaffected by adenosine diphosphate, 2,4-dinitrophenol, bovine serum albumin, or glutathione. Endogenous respiration of tissue slices is not stimulated by 2-4-dinitrophenol. It is suggested that brown fat mitochondria are not capable of oxidative phosphorylation, but do phosphorylate at the substrate level. Since these findings provide an unusual example of electron transport by means of an energetically nonconservative pathway, their significance to thermogenesis by brown adipose tissue is particularly emphasized. PMID- 4224266 TI - Hematoma of the rectus abdominis muscle complicated by anticoagulation therapy. PMID- 4224268 TI - [Vacations for the disabled]. PMID- 4224267 TI - Electrocardiographic changes reflecting left atrial abnormality in hypertension. PMID- 4224269 TI - [Histological and histochemical studies on gingival hypertrophy and hyperplasia]. PMID- 4224271 TI - The ionic requirements for the development of contracture in isolated slow muscle fibres of the frog. PMID- 4224270 TI - The proteolysis of fibrinogen by plasmin: the identification of thrombin clottable fibrinogen derivatives which polymerize abnormally. PMID- 4224272 TI - Paroxysmal electrical activity in the isolated forebrain of the frog (rana temporaria). Comparative pathophysiology of the thalamic pacemaker of paroxysmal activity. PMID- 4224274 TI - The reactibility of rats with defined susceptibility to an acoustic epileptogenic stimulus--to some acoustic and optic stimuli. PMID- 4224273 TI - Comparative pathophysiology of the paroxysmal EEG. Laminar analysis of the electrogenesis of spike and wave activity in the frog telencephalon. PMID- 4224275 TI - The effect of thalamic spreading depression on conduction in the visual and auditory pathways. PMID- 4224276 TI - The effect of isoprenaline pretreatment on the size of acute myocardial necrosis induced by the same drug. PMID- 4224277 TI - Effect of chronic systemic hypoxia of the methaemoglobin type on the rat myocardium and its resistance to anoxia. PMID- 4224278 TI - The respiratory metabolism of liver tissue slices and the total respiratory metabolism in rats after partial hepatectomy. PMID- 4224279 TI - Changes in the content of proteins, nucleic acids and the histological picture of the thyroid gland during the postnatal period in the rat. PMID- 4224280 TI - [Vestibular analysor--a critical organ for the evaluation of radiation hazards in space flights. (Effect of a wide-dosage-range ionizing radiation on the physiological functions of the cupular apparatus)]. PMID- 4224281 TI - Changes in erythropoiesis after whole-body x-irradiation in rats and rabbits. PMID- 4224282 TI - The role of erythropoietin in changes of erythropoiesis after x-irradiation in rats and rabbits. PMID- 4224283 TI - A device for measuring isometric contractions mechanoelectrically. PMID- 4224284 TI - [Better and cheaper at home]. PMID- 4224285 TI - Supravalvular mitral stenosis associated with ventricular septal defect, subvalvular aortic stenosis and double aortic arch. PMID- 4224286 TI - Endocardial fibroelastosis of the right ventricle in the newborn. Presenting the clinical picture of the hypoplastic right heart syndrome. PMID- 4224287 TI - Cystinuria associated with mongolism and identification of an abnormal pyrrolidine compound in urine. PMID- 4224289 TI - Methoxychlor toxicity. Comparative studies in the dog and the swine. PMID- 4224288 TI - Subcellular changes in surface adenosine triphosphatase activity of human liver in extrahepatic obstructive jaundice. PMID- 4224290 TI - Piglet birthweights and the order of farrowing. AB - The relationship between birthweight and order of farrowing was determined from the records of 202 attended farrowings. Statistical analysis of all individual birthweights showed the first-born piglet to be heavier (P<0.05) than the last born. The order of farrowing might not be entirely random, as further evidenced by a delayed expulsion of stillborn piglets; 70 per cent of these births occurred during the last third of the farrowing period. PMID- 4224291 TI - Plaque formation by Teschen disease virus and the effect of certain associated factors. AB - A plaque assay method was developed for Teschen disease virus using primary pig kidney cultures in which neutral red stain was incorporated in the agar overlay medium. Certain factors associated with the plaque-forming ability of the virus were standardized. Cultures allowed to adsorb the virus for 45-60 minutes at 28 and 37 C, gave maximal plaque count. The virus infected the cellular layer through the agar medium. Plating efficiency of the virus was enhanced by using a small volume of inoculum. Addition of serum to the medium was not required. Neutral red concentration in the agar overlay medium affected the number of plaques. Statistical analysis demonstrated the uniformity of the plaque counts and their linear relationship to virus concentration. Isolation of the virus by the plaque technique from infected spinal cord supernatant fluid was achieved. PMID- 4224292 TI - Studies on transmissible gastroenteritis of swine. II. Selected characteristics of a cytopathogenic virus common to five isolates from transmissible gastroenteritis. AB - Five cell culture isolates from transmissible gastroenteritis (TGE) of swine have been studied. There is a cytopathogenic virus common to all of these isolates. Some of the characteristics of this virus, such as its size, approximately 100 mmicro, its relative sensitivity to ether, lability at pH 2, pH 3, and pH 10, and its heat lability suggest that it may be a member of the myxovirus class. Concurrent research in this laboratory indicates that this cytopathogenic virus is not the only virus involved in the etiology of TGE, but it appears to be associated with many of the outbreaks of TGE which have been studied by this laboratory. PMID- 4224293 TI - Studies of Escherichia coli in gnotobiotic pigs. I. Experimental reproduction of colibacillosis. AB - The successful experimental production of colibacillosis in young gnotobiotic pigs by the oral administration of E. COLI (08:K.:H21 was accomplished. Colibacillosis was not produced in gnotobiotic pigs infected with either of the 2 other strains of E.COLI employed.Necropsy observations were presented and discussed. Emphasis was placed on the absence of grossly visible enteritis in pigs that died in the acute phase of the disease. The gross appearance of the intestinal tract changed some hours after death to resemble that associated with enteritis.Bacteremia was detected in the gnotobiotic pigs orally infected with each of the 3 strains of E. COLI, and the special characteristics of the colostrum-deprived pig were stressed as important factors in these findings. PMID- 4224294 TI - [Why does premenstrual acne vulgaris occur almost regularly? (Attempted explanation with a contribution to the endocrinology of sex hormones)]. PMID- 4224295 TI - Bacteria in acne lesions. PMID- 4224296 TI - Down syndrome and congenital leukemia. PMID- 4224297 TI - [Mucopolysaccharidosis]. PMID- 4224298 TI - [Mucopolysaccharidosis with elimination of heparitine-sulfate (polydystrophic oligophrenia)]. PMID- 4224299 TI - [Cerebral biopsy in a case of H. S. mucopolysaccharidosis. (Polydystrophic oligophrenia or Sanfilippo's disease). Histochemical and ultrastructural study]. PMID- 4224300 TI - Repair of potentially lethal damage in x-irradiated HeLa cells. PMID- 4224302 TI - [Lymphocytic lymphoma associated with alopecia mucinosa]. PMID- 4224301 TI - Sudden death from bronchial asthma. PMID- 4224303 TI - Erosion of the teeth. PMID- 4224304 TI - [Contribution to the knowledge of the structure and formation of comedones]. PMID- 4224305 TI - Digitonin precipitable steroids in normal human urine. PMID- 4224306 TI - Thin-layer chromatography of 17-ketosteroid 2,4-dinitrophenylhydrazones. PMID- 4224307 TI - Excretion of 16-alpha-hydroxysteroids by premature infants. PMID- 4224309 TI - Double beds and backache. PMID- 4224308 TI - A histochemical study of polyphosphate hydrolases in epidermal dendritic cells. PMID- 4224311 TI - [Expert testimony in the workmen's compensation organization. X]. PMID- 4224310 TI - Histochemical study of dentin in hydrocoritsone- and fluoride-treated rats. PMID- 4224312 TI - The excretion of taurine during deoxypyridoxine administration in Downs' syndrome patients and controls. PMID- 4224313 TI - Generalized aminoaciduria in the magnesium deficient rat. PMID- 4224314 TI - Epiphyseal growth zones in acute lathyrism. Determinations of water, hydroxyproline and mucopolysaccharides. PMID- 4224315 TI - [Post partum heart disease]. PMID- 4224316 TI - [Submicroscopic structure of heart valves changed by inflammation]. PMID- 4224317 TI - [Coronary blood supply in valvular insufficiencies of the left heart]. PMID- 4224318 TI - [Congenital heart valve insufficiency]. PMID- 4224319 TI - [Histochemical investigations in case of mandibular osteoclastoma]. PMID- 4224320 TI - Light sensitization and peroxides in sweat. PMID- 4224321 TI - A quantitative study of muscle factors in the chronic low back syndrome. PMID- 4224322 TI - Biochemical changes in the brain in rats poisoned with an alkymercury compound, with special reference to the inhibition of protein synthesis in brain cortex slices. PMID- 4224323 TI - The death adder (Acanthophis antarcticus): the effect of the bite and its treatment. PMID- 4224324 TI - [Expert testimony in compensation insurance. II. The causative active factors and their relations]. PMID- 4224325 TI - [On the ultrastructure of staphylococcal phages, the mode of infection and changes in staphylococci following phage infection]. PMID- 4224326 TI - Haemagglutination inhibition by antibody to host material of fowl plague virus grown in different tissues of chick chorioallantoic membranes. PMID- 4224327 TI - The significance of cardiac murmurs in anemia. PMID- 4224328 TI - Controlled relaxation. II. Clinical management of muscle-relaxant administration. PMID- 4224329 TI - Total-skin electron-beam therapy of lymphoma cutis and generalized psoriasis: clinical experiences and adverse reactions. PMID- 4224330 TI - A new practical back brace. PMID- 4224331 TI - Cardiovascular malformation and hydramnios. PMID- 4224332 TI - Total anomalous pulmonary venous drainage into the azygos vein. PMID- 4224334 TI - Adenosinetriphosphatase activity of cardiac myosin. Comparison of the enzymatic activities and activation by actin of dog cardiac, rabbit cardiac, rabbit white skeletal and rabbit red skeletal muscle myosins. PMID- 4224333 TI - [High-dose fibrinolytic treatment]. PMID- 4224335 TI - A cholera epidemic without a hospital death. PMID- 4224336 TI - A comparison of plasma lipoprotein levels in Asians, Africans and Europeans. PMID- 4224337 TI - Epidemiology of fractures in the Chinese children of Singapore. PMID- 4224338 TI - An epidemiological study of humeral fractures in Singapore. PMID- 4224340 TI - Veterinary parasitology in Malaysia with reference to cattle problems. PMID- 4224339 TI - Responses of large and small intestine of the rat to cesium, 5-hydroxytryptamine ouabain and acetyl choline. PMID- 4224341 TI - Progressive eradication of malarial disease in New Guinea. Experience in Maprik. PMID- 4224342 TI - Plasmodium inui-like infection producing a presumably fatal illness in a leaf monkey Presbytis johnii--a previously undescribed host. PMID- 4224343 TI - Separation of P. Berghei antigens by disc electrophoresis. PMID- 4224344 TI - Haemagglutination tests in malaria and toxoplasma: observations on sedimentation patterns. PMID- 4224345 TI - The application of fluorescent antibody test to Balantidium coli using fluorescent isothiocyanate and rhodamine isothiocyanate. PMID- 4224346 TI - A demonstration of the use of the polygraph to record Schultz-Dale reactions utilizing sera of monkeys infected with Brugia malayi as sources of both antibody and antigen. PMID- 4224347 TI - A note on the preferred A. aegypti breeding habitats in urban areas in Malaysia. PMID- 4224348 TI - Development of Wuchereria bancrofti in the domestic cat. PMID- 4224349 TI - A note on an egg parasite of Megymenum subpurpurascens West (pentatomidae: Rhyncheta). PMID- 4224350 TI - Studies on filariasis in New Guinea. Observations on periodicity. PMID- 4224351 TI - A double infection of filariasis in a black panther (Panthera pardus) from Pahang. PMID- 4224352 TI - A new filarial worm in the heart of a forest rat (Rattus sabanus). PMID- 4224353 TI - A sheathed microfilaria from a tree-shrew (Tupaia glis). PMID- 4224354 TI - Ascaris lumbricides eggs in liver and lungs of 2-year-old boy at necropsy. Confirmation by experimental inoculations of animals. PMID- 4224355 TI - Comparative susceptibility of primitive and higher primates to infection with Angiostrongylus cantonensis (Nematoda: Metastrongylidae). PMID- 4224356 TI - Comparison of developmental rates of two strains of Angiostrongylus cantonensis in the same laboratory-bred final hosts. PMID- 4224357 TI - Studies on Stephanofilaria kaeli in cattle. PMID- 4224358 TI - Histopathology of Stephanofilaria kaeli lesions in cattle. PMID- 4224359 TI - A study of the Nematode parasites of cockroaches in Singapore. PMID- 4224360 TI - Demonstration of a Nematode, Muspicea Sp., from the skin of laboratory mice. PMID- 4224361 TI - Possible sources of human infection with Opisthorchis and Paragonimus in Malaya. PMID- 4224362 TI - Life cycle of a new Plagiorchid from Bulbuls and Swifts experimentally maintained in White-headed Munias and white mice. PMID- 4224363 TI - Differenation of Trematode cercariae of the Genus Plagiorchis by use of the patterns of their argentophilic cuticular structures. PMID- 4224364 TI - Miracidial maze. Use of a free-choice system to test Echinostome miracidia in their relative attraction towards normal and abnormal snails hosts, living, dead, whole, and dissected snails. PMID- 4224365 TI - Lung infection of rat with Cysticercus fasciolaris. PMID- 4224366 TI - A Malayan record of Temnocephala semperi Weber (Rhabdocoela, Temnocephalidae), an ectocommensal turbellarian on the freshwater crab Potamon rafflesi Roux. PMID- 4224367 TI - [Glycogenic disease of the heart]. PMID- 4224368 TI - [Activities of the Namangan interregional glaucoma service]. PMID- 4224369 TI - [Water load and intraocular tension in patients with glaucoma under the continental climatic conditions in Uzbekistan]. PMID- 4224370 TI - Ambulation of "ambulatory" handicapped patients. PMID- 4224371 TI - Hurler's syndrome. Effect of retinol (vitamin A alcohol) on cellular mucopolysaccharides in cultured human skin fibroblasts. AB - Skin fibroblasts from eight families with Hurler's syndrome (X-linked recessive and autosomal recessive) and normal individuals have been studied in cell culture. A good correlation between cellular metachromasia and the quantitative estimation of intracellular mucopolysaccharides was observed provided the culture conditions were standardized. In both forms of Hurler's syndrome intracellular mucopolysaccharide content could be used to distinguish the affected individual and the carrier from the normal subject, although the total mucopolysaccharide content of fibroblast cultures or the amount in the culture medium did not permit such a distinction. Retinol, in concentrations similar to those encountered in man in hyper-vitaminosis A, caused a reduction in total mucopolysaccharide content of fibroblast cultures from normal and affected individuals. Cultures from three patients with the X-linked recessive form of Hurler's syndrome showed a gradual but marked decrease in cellular metachromasia and approximately 60% decrease in mucopolysaccharide content. Synthesis of polysaccharides and sulfation appeared to be equally affected. On removal of retinol from the medium the content of intracellular mucopolysaccharides returned to pretreatment levels. The possible relevance of these findings to the treatment of Hurler's syndrome is discussed. PMID- 4224372 TI - [Epidemiologic patterns of taeniarhynchosis foci formation in the Azerbaijan SSR and problems of eradication of this helminthic disease]. PMID- 4224373 TI - [Ecologic features of a natural focus of trichinellosis in a semidesert-steppe zone of Kazakhstan]. PMID- 4224374 TI - [An experience of Jakhroma hospital in reducing sharply the incidence of ascaridosis among the population of the area]. PMID- 4224375 TI - [Occurrence and seasonal incidence of the activity of Ioxodes persulcatus in the Kurgan region]. PMID- 4224377 TI - The response of various skin lesions to oral sulfur--35. PMID- 4224376 TI - [Activity of reactions for acid mucopolysaccharides in cancer of the colon and rectum]. PMID- 4224378 TI - Ultrastructure of myocardium in physiological hypertrophy of the heart in rats. PMID- 4224379 TI - [Retrospective serological examination of the population in leptospirosis foci]. PMID- 4224380 TI - [Results of serological examination for Q-fever in various groups of the Kirghiz SSR population]. PMID- 4224381 TI - [The chronic carrier state in typhoid and paratyphoid fevers]. PMID- 4224382 TI - [The epidemiological significance of some biological peculiarities of Sonne dysentery]. PMID- 4224383 TI - [Epidemiological analysis of a typhoid fever outbreak and detection of typhoid carriers]. PMID- 4224384 TI - Concentrations of amino acids in plasma and muscle. Relationship to androgen metabolism during growth and development in the male. PMID- 4224385 TI - [Influence of the solvent on the activity, in the ascidian egg, of a fluorescent hydrocarbon, benzopyrene]. PMID- 4224386 TI - [Induction of tissue disorders in insects by change of balance of pterin-like growth factors--growth hormones and mechanism of this induction]. PMID- 4224388 TI - [Variations in the allometry levels and the indices of origin in a series, and their supposed relationship]. PMID- 4224389 TI - [Allometry of thepereiopode VII during its development in Ligia oceanica (L.), Crustacea, Isopoda]. PMID- 4224390 TI - [Change in hepatic transmembrane potentials of rats under the influence of thyroidectomy and adrenalectomy]. PMID- 4224391 TI - [A metastasizing fibroblastic sarcoma of the gastric serous mmbrane, transplantable]. PMID- 4224387 TI - [Study of regeneration in Asterina gibbosa Penn. (Echinodermata, Asteroidea) by the method of x-ray irradiation]. PMID- 4224393 TI - [Biogenesis of histamine in the gastric mucosa of rats deficient in proteins and pyridoxine]. PMID- 4224392 TI - [Mechanism of the reinforcement of excitability of the respiratory centers to CO2 under the influence of a weak hypoxia]. PMID- 4224395 TI - [Porphyria and decline of the hepatic synthesis of ATP induced in white rats by sodium malonate. Therapeutic effect of ATP and AMP]. PMID- 4224394 TI - [Action of various neuroleptic and tranquilizing agents on the sensitivity of the central nervous system to acetylcholine, adrenalin and serotonin]. PMID- 4224396 TI - [Production in rabbits of malformations of the extremities by administration of azathioprine and 6-mercaptopurine]. PMID- 4224397 TI - [Effects of ablation of the olfactory and optic rudiments on the nasolacrymal canal of Discoglossus pictus Otth]. PMID- 4224398 TI - [Mullerian canal and maternal ovary]. PMID- 4224399 TI - [Study of some endocrine reactions accompanying obesity induced in AkR mice by gold thioglucose]. PMID- 4224400 TI - [In vitro liberation of heparin from the basophil granulocytes of rabbits by promethazine]. PMID- 4224401 TI - [Induced erythrocyte aggregates and shock caused by removal of a tourniquet]. PMID- 4224402 TI - [Estimation in man of the inertia of ventilated gas]. PMID- 4224403 TI - [Seromucoids: average levels and variance according to age in sheep]. PMID- 4224404 TI - [Trehalase activity of human serum in adults]. PMID- 4224405 TI - [Study of the action of chorionic gonadotropin on the biosynthesis of androgens by the guinea pig ovary]. PMID- 4224406 TI - [On the antagonism between the inhibitors of the biosynthesis of purines: azaserine and cycloserine, and the natural formiminated derivatives during the in vivo growth of cells of the Ehrlich ascites tumor]. PMID- 4224407 TI - [Research on the iodoproteins of a tunicate: Ciona intestinalis L]. PMID- 4224408 TI - [Urinary excretion of adrenalin, noradrenalin and dopamine during the 2 hours following the administration of amphetamine]. PMID- 4224409 TI - [Definitive placement of an electrode on the round window of guinea pigs]. PMID- 4224410 TI - [Hypothalamic electric activity in rats at the time of food conditioning]. PMID- 4224411 TI - [Mediastinal lymphoma of Swiss mice receiving urethane. IV. Adaptation to the graft. Electron microscopic cytologic study]. PMID- 4224413 TI - [Creation of a pseudo-aleatory signal, of simple application, usable in tracking tests]. PMID- 4224412 TI - [Action of ionizing radiations on HeLa cells. 3. Persistance of anabolism (augmentation of dry weight)]. PMID- 4224414 TI - [Experimental study of the cytology of the anterior lobe of the hypophysis in dogs]. PMID- 4224415 TI - [Contribution of the method of selective precipitation with trichloracetic acid in the histophysiologic study of the hypophysis of a Teleost: Mugil cephalus L]. PMID- 4224416 TI - [Influence of experimental conditions on the action which certain psycholeptic drugs exercise on the behavior of the praying mantis]. PMID- 4224417 TI - [Some properties and characteristics of ovoverdine]. PMID- 4224418 TI - [Immunology of bronchial secretions in cancers of the lung]. PMID- 4224419 TI - [Further observations on IMAO-serotonin interactions on the agitation induced by morphine in albino mice]. PMID- 4224420 TI - [Influence of electromagnetic radiation from a RADAR EMITTER ON THE PHAGOCYTIC FUNCTION OF CELLS OF THE RETICULOENDOTHELIAL SYSTEM IN CONTACT WITH THE BLOOD IN MICE]. PMID- 4224422 TI - [The motor control of the esophagus during rumination]. PMID- 4224421 TI - [Actions of different hypertonic solutes on the vasomotivity of the musculocutaneous area in dogs]. PMID- 4224423 TI - [Comparative role of the muscles of the nasopharynx and the glottis in inspiration of so-called "closed glottis" rumination]. PMID- 4224424 TI - [Local microelectrophoretic application of H+ ions and variations of the bioelectric parameters of the neuron membrane]. PMID- 4224425 TI - [On 2 stages of the catabolism of gamma-guanidobutyric acid in vertebrates]. PMID- 4224426 TI - [Action of temperature on the sex ratio in the Agama agama (Agamidae, Lacertilia) embryo]. PMID- 4224427 TI - [Electrocardiogram of adrenalectomized rats at low temperature]. PMID- 4224428 TI - [Influence of the musculature on the differentiation of the digestive mucosa during cicatrisation: study after gastroduodenal anastomosis in rats]. PMID- 4224429 TI - [Demonstration of a neuro-endocrine determinism of laying induced by hemicastration in rats]. PMID- 4224431 TI - [Method of exploration of dietary behavior in a hibernating animal, the lerot Eliomys quercinus]. PMID- 4224430 TI - [Study of the combined action of dexamethasone phosphate and glucose on the mitotic index of cardiac fibroblast cultures]. PMID- 4224432 TI - [Effects of the stimulation of the cervicodorsal spinal cord on the gallbladder in the common carp (Cyprinus carpio L.)]. PMID- 4224433 TI - [Inhibitory effect of white light on the "spontaneous" locomotor activity of drosophila (Drosophila melanogaster Meigen)]. PMID- 4224434 TI - [Quantitative study of the facilitation exercised by vibratory stimulation on the geokaryokinesis and photokaryokinesis of Drosophila melanogaster Meigen]. PMID- 4224435 TI - [Lesions of the digestive system determined by forced immobilization in pigs]. PMID- 4224436 TI - [Influence of hypocapnic gaseous alkalosis on the effects of sympathomimetic vasconstrictors and sympathomimetic vasodilators]. PMID- 4224437 TI - [Influence of nitrogen nutrition on the growth, sporulation and morphology of Keratinomyces ajelloi Vanbr]. PMID- 4224438 TI - [Action of embryonic inductors on tumorous tissue]. PMID- 4224439 TI - [Activity of nucleic acids from normal and tumorous tissue]. PMID- 4224440 TI - [Bioelectric activity of the olfactory bulb of the opossum, Didelphis azarae]. PMID- 4224441 TI - [Role of the adrenal glands and the hypophysis in the action of hypoxia on thyroid function]. PMID- 4224442 TI - [Demonstration of iron obsorption in hyperthyroid patients]. PMID- 4224443 TI - [Action of progesterone on the oxytocic effect of 17-beta-estradiol]. PMID- 4224444 TI - [Neoformation of the islands of Langerhans in rats by the action of DL ethionine]. PMID- 4224445 TI - [Electrocorticographic study of sleep in the opossum Didelphis azarae]. PMID- 4224446 TI - [Nuclear protein, desoxyribonucleic acid and nucleolar material content in cells of various origins]. PMID- 4224447 TI - [Comparative action of polybrene on shock induced by dextran and by specific antigen in rats]. PMID- 4224448 TI - [Influence of the density of acoustic support on the human voice]. PMID- 4224449 TI - [Presence of 3 isozymes hydrolyzing L-leucyl-beta-napthylamide in normal human serum]. PMID- 4224450 TI - [Drainage of myocardial and adrenal catecholamines in rats treated with pargyline]. PMID- 4224451 TI - [On the adrenal medulla stimulation induced in rats by glucagon]. PMID- 4224452 TI - Spontaneous atlanto-axial dislocation in a mongoloid child with spinal cord compression. Case report. PMID- 4224453 TI - The return of the injured worker to work. PMID- 4224454 TI - [Parodontopathy appearing with Down's syndrome]. PMID- 4224455 TI - Effect of adrenal steroids on a Na+- and K+-requiring adenosine triphosphatase from rat kidney. PMID- 4224456 TI - The plasmin inhibitor of human plasma. IV. Its action on plasmin, trypsin, chymotrypsin, and thrombin. PMID- 4224457 TI - Treatment of cancer patients with infusions of plasmin. PMID- 4224458 TI - Cardiac size and pulmonary arteriography in experimental chronic hypoxia. PMID- 4224459 TI - Cerebral oxygen consumption in Down's syndrome. PMID- 4224460 TI - [Practical suggestions for the psychological treatment of children in dental practice]. PMID- 4224461 TI - Some general observations on the usefulness of lysergic acid in psychiatry. PMID- 4224462 TI - [Familial cardiomegaly in adolescence due to glycogen storage]. PMID- 4224463 TI - Pathologic physiology of valvular regurgitation. PMID- 4224464 TI - [The 2d Leningrad Mental Hospital under conditions of the siege of Leningrad]. PMID- 4224465 TI - The first appointment. PMID- 4224466 TI - Children's dentistry--present and future trends. PMID- 4224467 TI - Health or medical questionnaire. PMID- 4224468 TI - [The task of pedodontics in the oral rehabilitation of children with hare lip and velo-palatine cleft]. PMID- 4224470 TI - In vivo parathyroid hormone status as related to respiration, phosphorylation and ion transport in rat kidney mitochondria. PMID- 4224469 TI - Idiopathic and disseminated eczema. PMID- 4224471 TI - Steroid hormone transformations by endocrine organs from pregnant mammals. I. Estrogen biosynthesis by mammalian placental preparations in vitro. PMID- 4224472 TI - Crystallization and properties of rabbit skeletal muscle phosphofructokinase. PMID- 4224473 TI - Further analysis of the mode of inhibition and activation of Novikoff ascites tumor phosphofructokinase. PMID- 4224475 TI - The determination of urinary androsterone, etiocholanolone, and dehydroepiandrosterone in the normal male rhesus monkey. PMID- 4224474 TI - Catalysis of the direct transfer of oxygen from nicotinamide N-oxide to xanthine by xanthine oxidase. PMID- 4224476 TI - [Are there still indications for tibio-fibular bolting? (After the long term results of 23 cases)]. PMID- 4224477 TI - [Traumatic radial paralysis (35 cases)]. PMID- 4224478 TI - [Mobilizing operations of stiffness and ankylosis of the elbow]. PMID- 4224479 TI - [Tarso-metatarsal luxations]. PMID- 4224480 TI - [Results of 20 osteo-periosteal decortications according to Judet's technic]. PMID- 4224481 TI - [Congenital elevation of the omoplate]. PMID- 4224482 TI - [A new procedure for treatment of acromio-clavicular luxation]. PMID- 4224483 TI - [The treatment of the adhesive disease of the abdomen]. PMID- 4224484 TI - Metabolic factors in the cardiac insufficiency of arteriovenous fistula. PMID- 4224486 TI - Trasylol. PMID- 4224485 TI - Mitral valve replacement in a child during active rheumatic carditis: successful management of sixteen episodes of ventricular fibrillation. PMID- 4224487 TI - Studies on Southeast Asian Haemaphysalis ticks (Ixodoidea, Ixodidae). Species described by Supino in 1897 from Burma, with special reference to H. (Rhipistoma) asiaticus (= H. dentipalpis Warburton and Nuttall). PMID- 4224488 TI - [Treatment of syphilis]. PMID- 4224489 TI - [Considerations on hemorrhagic rectocolitis]. PMID- 4224490 TI - [Methochlopramide in digestive radiology in a military milieu]. PMID- 4224491 TI - [Molecular radiobiology. The role of chemical species derived from water]. PMID- 4224492 TI - [Medical research in the American Army]. PMID- 4224493 TI - [Use of lithium hydroxide as an absorbent of carbon dioxide. Value in aviation and space flight]. PMID- 4224494 TI - [Significance of vectorcardiography in the evaluation of hypertrophy of the heart ventricles in patients with ventricular septal defect]. PMID- 4224495 TI - [Mass outbreak of trichinelliasis from meat of wild boar in the Uzbek SSR]. PMID- 4224496 TI - [Differentiation of pathogenic Staphylococci isolated from wounds of patients and from the pharynx and nose of hospital personnel by phagetyping method]. PMID- 4224497 TI - Alzheimer's disease in late adult life. PMID- 4224498 TI - Giant left atrium as a cause of dysphagia. PMID- 4224499 TI - On the question of obstruction in idiopathic hypertrophic subaortic stenosis. PMID- 4224500 TI - Sexual impotence in men having low-back syndrome. PMID- 4224501 TI - Giant T wave inversion. PMID- 4224503 TI - Clothing for the handicapped. PMID- 4224502 TI - The experimental approach to the treatment and upbringing of handicapped children. PMID- 4224504 TI - Post-traumatic neurosis in industry. PMID- 4224506 TI - The problem from the standpoint of the physician. PMID- 4224505 TI - Current Wisconsin legal concepts in industrial psychoneurosis. PMID- 4224507 TI - Responsibilities of the physician in workmen's compensation cases. PMID- 4224509 TI - [Occupational diseases and poisoning in Warsaw in 1962-1963. An epidemiologic analysis]. PMID- 4224508 TI - Hemodynamic fndings in acute glomeruloenphritis. PMID- 4224510 TI - Hepatopexy for chronic cirrhotic ascites. PMID- 4224511 TI - [Treatment of gynecologic diseases at the Tsaishi health resort]. PMID- 4224512 TI - [V. K. Beletskii (on his 70th birthday)]. PMID- 4224514 TI - Extraction of contractile proteins from myofibrils prepared by rate-zonal centrifugation. PMID- 4224513 TI - Aldosterone and sodium-potassium-dependent ATPase activity of rat kidney membranes. PMID- 4224515 TI - Unusual dermatolyphics associated with major congenital malformations. PMID- 4224516 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 53-1966. PMID- 4224517 TI - [Chronic bronchitis and emphysema in the USA]. PMID- 4224518 TI - [Reporting and compensation procedures of occupational diseases and their statistical comprehension in the USA]. PMID- 4224519 TI - Degenerative joint disease of the lumbar spine in coal miners--a clinical and x ray study. PMID- 4224520 TI - Ankylosing spondylitis with widespread arteritis. PMID- 4224521 TI - Oscillations of glycolytic intermediates in yeast cells. PMID- 4224522 TI - Induction in Escherichia coli 15 of the colicinogenic factor by thymine-less death. PMID- 4224524 TI - [On occupational dermatoses in the wood-manufacturing industry]. PMID- 4224523 TI - Comparative studies of the MG activated ATPase activity and Ca uptake of fractions of white and red muscle homogenates. PMID- 4224525 TI - Studies on cytotropism in animal viruses. 3. Growth of influenza virus in epithelial-like and fibroblastic cells derived from chick embryo lung. AB - Stewart, Robert B. (University of Rochester, Rochester, N.Y.), and Paul H. Frickey. Studies on cytotropism in animal viruses. III. Growth of influenza virus in epithelial-like and fibroblastic cells derived from chick embryo lung. J. Bacteriol. 92:972-977. 1966.-Growth of the PR8 strain of influenza virus was studied in epithelial-like and fibroblastic cell cultures derived from chick embryo lungs. The cells were found to differ in morphology, staining characteristics, and in their ability to support production of infectious influenza virus. Fibroblastic cells were characterized by their spindle shape, content of a mucopolysaccharide, their relative inability to synthesize infectious influenza virus, and production of a cell-associated noninfectious hemagglutinin. Epithelial-like cells were characterized by their polygonal shape, absence of mucopolysaccharide, and ability to synthesize infectious influenza virus. PMID- 4224526 TI - Fibrinolytic and thrombolytic therapy. PMID- 4224527 TI - [Histo-enzymatic examinations of the lung in experimental hydrogen sulfide poisoning]. PMID- 4224528 TI - The Mg2+--influence on the antibody biosynthesis in vitro inhibited by tetracyclines and chloramphenicol. PMID- 4224529 TI - Inquiries into the insulin influence on the respiration and the synthesis of adenosine triphophate in cell nuclei isolated from thymus glands of calves. PMID- 4224531 TI - Disturbances in the intensity of protein synthesis when the organism repeatedly comes into contact with streptococcal infection. PMID- 4224530 TI - On infections of tonsillar and odontic origin in the etiopathogenesis of experimental streptococcal myocarditis. PMID- 4224532 TI - [On a case of transposition of the left coronary artery into the pulmonary artery (White-Bland-Garland syndrome)]. PMID- 4224533 TI - Inquiries into the tuberculin sensitivity among medical students. PMID- 4224534 TI - On the efficiency of the aqueous and alcoholic methods of morphine and strychnin extraction from visceral parts, when mixed with animal charcoal. PMID- 4224535 TI - Assay of antibody production by surviving cells dispersed in agar gel. PMID- 4224536 TI - [Attendance, hospitalization and mortality of the rural population (Based on data from 3 regions of the Belorussian SSR)]. PMID- 4224537 TI - The distribution of hydroxysteroid dehydrogenase in human sebaceous glands. PMID- 4224538 TI - Mucopolysaccharides in mast cells. PMID- 4224539 TI - An unusual abdominal flap. PMID- 4224541 TI - [Pediatricians in the care of handicapped]. PMID- 4224540 TI - The influence of bilirubin on oxidative phosphorylation and related reactions in brain and liver mitochondria: effects of protein-binding. PMID- 4224544 TI - [Stomatological aid in the antitubercular dispensary of the Republic]. PMID- 4224543 TI - [A method for the estimation of the activity in consultation-rooms of pediatric stomatology]. PMID- 4224542 TI - Spontaneous functional closure of symptomatic atrial septal defects. PMID- 4224545 TI - [Disclosure of struvite in codfish cans]. PMID- 4224546 TI - [Study of the proteins and glycoproteins of the compact bone of rabbits]. PMID- 4224547 TI - [Origin and development of the urogenital connections in the male domestic rabbit (Oryctolagus cuniculus L.)]. PMID- 4224548 TI - [Identification of a phasic electrophysiological activity independent of the paradoxical phase of sleep in rats]. PMID- 4224549 TI - [Relation between the electrical and mechanical activities of the intestines during absorption. Study with anesthetized rats and guinea pigs]. PMID- 4224550 TI - [Influence of the outside temperature on the elimination of urinary catecholamines in hamsters (Cricetus cricetus)]. PMID- 4224551 TI - [Elimination of iodine-131 in the submaxillary and parotid saliva of hypophysectomized dogs]. PMID- 4224552 TI - [Effect of the mode of transportation on the potency of smallpox dermovaccine in glycerin]. PMID- 4224553 TI - [Influence of some factors on the morphology of colonies of L-form hemolytic streptococci]. PMID- 4224554 TI - [On the effect of tetracycline antibiotics. 13. Absence of tellurium reductase in oxytetracycline-resistant strains of Escherichia coli and Staphylococcus aureus]. PMID- 4224555 TI - [Rapid biochemical methods for the differentiation of Brucella suis and Brucella abortus]. PMID- 4224557 TI - [Disinfection of patients' rooms using peracetic acid]. PMID- 4224556 TI - [Relation of Clethrionomys glareolus Schr. and Apodemus flavicollis Melch. to the virus of tick-borne encephalitis in 2 different biotopes]. PMID- 4224558 TI - [A study on the toxicity of medical rubber plugs against mallalian tissue cultures and a suggestion for its suppression]. PMID- 4224559 TI - [Tick-borne encephalitis in the surroundings of Brno. I. Evaluation of some epidemiological data]. PMID- 4224560 TI - [The provisional genus Hafnia and its systemic classification within the tribe Enterobacteriaceae]. PMID- 4224561 TI - Glycolytic control mechanisms. II. Kinetics of intermediate changes during the aerobic-anoxic transition in perfused rat heart. PMID- 4224562 TI - Some early findings on the possibility of using Aedes togoi as a vector of Dirofilaria repens in the laboratory. PMID- 4224563 TI - The "Innenkorper" in differentiation between the microfilanriae of Brugia pahangi and B. malayi (sub-periodic form). PMID- 4224564 TI - A filarial parasite from the flying fox (Pteropus vampyrus). PMID- 4224565 TI - [Epidemiological efficacy of live influenza vaccine during the A2 and B influenza outbreaks in 1962]. PMID- 4224566 TI - Congenital cataract. PMID- 4224567 TI - The Nadi reaction and mental subnormality. PMID- 4224568 TI - Historical background of injury as it relates to the workmen's compensation law. PMID- 4224569 TI - Current concepts of injury under the workmen's compensation act--the problem from the standpoint of industry. PMID- 4224570 TI - Diagnostic value of phlebography in venous disorders of the lower extremity. PMID- 4224571 TI - [Mercurial diuretics and (sodium ion + potassium ion) activated ATPase in the kidney]. PMID- 4224572 TI - [The development of the musculature of the abdominal wall in Anura, Rana nigromaculata, and in some vertebrates]. PMID- 4224573 TI - [Reaction for acid mucopolysaccharides in the connective tissue around tumors and in the kidneys of rats with transplantable Guerin epithelioma]. PMID- 4224574 TI - [Coxa vara and "essential" cyst]. PMID- 4224575 TI - Some bioelectrical properties of Amoeba proteus. PMID- 4224576 TI - A study of maternal age in Down's syndrome. PMID- 4224577 TI - [On gymnastic lessons with physically handicapped children]. PMID- 4224578 TI - On the possible role of the thyroid in the control of the development of the mammalian brain. PMID- 4224579 TI - Urinary acid mucopolysaccharides in mastocytosis. A new technique for quantitative estimation. PMID- 4224580 TI - [Locacorten-vioform and sterosan-hydrocortisone--a double-blind study of their effects on infected eczemas]. PMID- 4224581 TI - [Seborrheic warts and their malignant degeneration]. PMID- 4224582 TI - [Soft X-ray irradiation of wide-spread seborrheic warts]. PMID- 4224584 TI - [Electrocardiographic and phonocardiographic changes in idiopathic heart hypertrophy with and without functional stenosis of the outflow]. PMID- 4224583 TI - [Vasculitis allergica cutis caused by phenylbutazone]. PMID- 4224585 TI - [Phenytoin (5,5-diphenylhydantoin) hypersensitivity presenting a clinical picture of scarlatiniform erythroderma]. PMID- 4224586 TI - Clot lysis with fibrinolysin: progress report. PMID- 4224587 TI - [Performance tests in persons with a leg handicap]. PMID- 4224588 TI - [Distal humeral fractures in childhood with special reference to late results]. PMID- 4224589 TI - [Results of conservative treatment of supracondylar humeral fractures in childhood]. PMID- 4224590 TI - [Late results following conservative treatment of humeral shaft fractures by means of Bohler's U plaster cast]. PMID- 4224591 TI - [Evaluation of 216 primary and 50 habitual shoulder joint luxations]. PMID- 4224592 TI - [A contribution to the bilateral shoulder luxation]. PMID- 4224593 TI - [Contribution to the roentgenology of the wrist]. PMID- 4224594 TI - [Luxation of the peritriquetrolunar bone]. PMID- 4224595 TI - [Statistical analysis of ski injuries]. PMID- 4224596 TI - [On the problem of stress damage at the preserved knee joint of patients with amputated femur. Report on the examination of 109 persons with amputated femur]. PMID- 4224597 TI - [Costal periostitis in fibrinous pleurisy following pneumonia and lung infarction]. PMID- 4224598 TI - [Studies on acid mucopolysaccharides in the urine. II. In collagen diseases]. PMID- 4224599 TI - Observations on the spine in mongoloidism. PMID- 4224600 TI - [On the incidence of requirement of special education for physically handicapped children and adolescents in the German Democratic Republic]. PMID- 4224601 TI - "Collagen disease" due to carbamazepine (Tegretol). PMID- 4224602 TI - Sensitization, immunological tolerance and desensitization of guinea pigs to neoarsphenamine. II. Influence of various factors on sensitization to NEO. PMID- 4224604 TI - Effects of maternal age and birth order on the risk of mongolism and leukemia. PMID- 4224603 TI - Toxoplasmin sensitivity: subnormality and environment. PMID- 4224605 TI - Light absorbance changes in pure mitochondria and other particulates of rat brain. PMID- 4224606 TI - [Column chromatographic fractionation of acid mucopolysaccharides in the urine]. PMID- 4224607 TI - [Effect of dimethyl sulfoxide(DMSO) on collagen and mucopolysaccharides of indurated skin of patients following telecobalt irradiation]. PMID- 4224608 TI - [Comparative studies on the effect of resorption promoting substances on the skin of the mouse during treatment with 3,4-benzopyrene]. PMID- 4224609 TI - Studies on oestriol synthesis from dehydroepiandrosterone sulphate in human pregnancy. PMID- 4224611 TI - Myocardiopathy in Chagas' disease. I. Comparative study of pathologic findings in chronic human and experimental Chagas' myocarditis. PMID- 4224610 TI - Vascular connective tissue under the influence of oestrogens. II. Reaction of the aortic wall to noradrenaline-induced injury in female and male rabbits. PMID- 4224612 TI - Clinical pathologic conference. PMID- 4224614 TI - [Changes in some histochemical reactions in the liver of the rat after exposure to ionizing x rays]. PMID- 4224613 TI - Vasoinhibitory action of proteolytic enzyme inhibitors in the capillary bed. PMID- 4224615 TI - [Improved resources for protection of the worker]. PMID- 4224617 TI - [Current problems of industrial medicine in Germany, in research, theory and at the working place]. PMID- 4224616 TI - [Prevention and compensation of silicosis in Morocco]. PMID- 4224618 TI - [Changes in the muscle spindles in neuromuscular diseases]. PMID- 4224620 TI - [Aleksei Alekseevich Zavarzin]. PMID- 4224619 TI - [Volf Alexandrovich Dorfman (1900-1965)]. PMID- 4224621 TI - The birth of mongoloids. PMID- 4224622 TI - [Growth deviations in children with Down's syndrome]. PMID- 4224623 TI - Studies on the adenosine triphosphatase activity of 14 S and 30 S dynein from cilia of Tetrahymena. PMID- 4224624 TI - Absence of effects of cardiac glycosides on cardiac myosin and A Ca++-sensitive reconstituted cardiac actomyosin. PMID- 4224625 TI - Stimulation of cerebrospinal fluid production by low doses of intraventricular ouabain. PMID- 4224626 TI - Work and heart disease in Wisconsin. II. Workman's compensation rules of practice. PMID- 4224627 TI - [Grey rats as hosts of intestinal pathogenic parasites]. PMID- 4224628 TI - Immunochemical studies of the circulating products of fibrinogenolysis in certain pathological conditions. PMID- 4224630 TI - The fibrinolytic enzyme system in the newborn. PMID- 4224629 TI - Histochemical investigation of ischemic villi in the placenta. PMID- 4224631 TI - [Health planning]. PMID- 4224632 TI - [Collection and use of statistical data in national and local health services]. PMID- 4224633 TI - [An experiment in teaching social anthropology at the School of Public Health, Santiago, Chile]. PMID- 4224634 TI - [Immunity to poliomyelitis virus in Costa Rica]. PMID- 4224635 TI - Hematoma of the rectus abdominis muscle during anticoagulant therapy. PMID- 4224636 TI - Control of the activity of highly purified cardiac actomyosin by Ca2+, Na+ and K+. PMID- 4224637 TI - An epidemiological assessment of bundle-branch block. PMID- 4224638 TI - Left atrial volume and its changes in heart disease. PMID- 4224639 TI - Biochemical changes in phytohemagglutinin stimulated human lymphocytes. PMID- 4224640 TI - The fine structure of the basal cell of human prostate. PMID- 4224641 TI - [Lumbalgia, psychosomatic aspects, "tired-out syndrome"]. PMID- 4224642 TI - [Surgical treatment of a pertrochanteric femoral neck fracture with Palacos]. PMID- 4224643 TI - [On an unusual form of pertrochanteric fracture and its treatment]. PMID- 4224644 TI - [The value of Mitella and Desault bandages (on useful bandaging technic in injuries of the shoulder and arm region and against abduction splints)]. PMID- 4224646 TI - [Accident and formation of renal calculi]. PMID- 4224645 TI - [On conservative and surgical treatment of renal injuries]. PMID- 4224647 TI - [Patellar dislocation to the bottom (horizontal luxation)]. PMID- 4224648 TI - [Trauma und coxarthrosis]. PMID- 4224649 TI - [On the frequency of carcinomatous degeneration of osteomyelitic fistulae]. PMID- 4224650 TI - [Animal experiments on the use of polyvinyl sponge as emergency dressing in burns]. PMID- 4224652 TI - [Findings 22 years after removal of a blood cyst of the left leg nerve]. PMID- 4224651 TI - [Clinical experiences with Cura-Tuell in injuries]. PMID- 4224653 TI - [Testing of the antiphlogistic effect of antirheumatic drugs]. PMID- 4224654 TI - An electromyographic diagnostic screening test in McArdle's disease and a case report. PMID- 4224655 TI - Steroid mediated changes of leucocyte alkaline phosphatase activity in Down's syndrome. PMID- 4224656 TI - [Occurrence of the Stevens-Johnson syndrome (erythema exudativum multiforme) and severe skin reactions with relation to sulfonamide therapy. Reply to questions sent to a Norwegian hospital]. PMID- 4224657 TI - Clinical definition of the Hurler-Hunter phenotypes. A review of 50 patients. PMID- 4224658 TI - Long bone growth in Down's syndrome. PMID- 4224659 TI - Continuous oscillations in a cell-free extract of S. carlsbergensis. PMID- 4224660 TI - Red cell membrane ATPase: radiation inactivation estimates of "size". PMID- 4224661 TI - Disorders of the hair and scalp. PMID- 4224662 TI - [Further data on the dissociation of the superprecipitation and ATPase activity of thrombosthenin prepared from frozen and lyophilized human platelets].